# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Lyase_1 PF00206.15 KKK11803.1 - 1.1e-88 297.4 0.0 1.5e-88 297.0 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KKK11803.1 - 1.5e-25 89.0 0.0 4.5e-25 87.5 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Acyl_transf_3 PF01757.17 KKK11822.1 - 2.4e-15 56.2 25.3 4.7e-15 55.2 17.5 1.4 1 1 0 1 1 1 1 Acyltransferase family 60KD_IMP PF02096.15 KKK11823.1 - 4.3e-40 137.5 0.1 7.3e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.6 KKK11823.1 - 6.6e-30 102.7 0.0 1.5e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Outer membrane protein TOM13 Sugar_tr PF00083.19 KKK11825.1 - 2.6e-44 151.5 24.9 8.2e-44 149.9 17.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK11825.1 - 1e-20 73.7 29.6 1e-20 73.7 20.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Nse4_C PF08743.5 KKK11827.1 - 1.1e-35 121.4 0.0 2.7e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KKK11827.1 - 3e-19 68.5 0.0 9.6e-19 66.9 0.0 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Cupin_8 PF13621.1 KKK11827.1 - 0.014 14.8 0.3 0.024 14.1 0.2 1.3 1 0 0 1 1 1 0 Cupin-like domain Peptidase_S64 PF08192.6 KKK11827.1 - 0.82 7.9 6.4 0.2 9.9 2.2 1.5 2 0 0 2 2 2 0 Peptidase family S64 DUF4336 PF14234.1 KKK11828.1 - 3.5e-16 59.2 0.0 4e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Isy1 PF06246.7 KKK11829.1 - 2.1e-78 263.2 0.1 2.5e-78 263.0 0.1 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 KKK11829.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 YolD-like protein MMR_HSR1 PF01926.18 KKK11830.1 - 6.6e-15 55.0 0.0 1.6e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KKK11830.1 - 5e-06 25.7 0.2 9.2e-06 24.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KKK11830.1 - 2e-05 23.9 0.1 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 KKK11830.1 - 0.00086 19.0 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 KKK11830.1 - 0.00094 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 KKK11830.1 - 0.0011 17.9 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.4 KKK11830.1 - 0.0022 17.4 0.6 0.38 10.2 0.0 3.4 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 KKK11830.1 - 0.0055 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KKK11830.1 - 0.0093 15.4 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KKK11830.1 - 0.0097 15.7 0.2 0.19 11.5 0.0 2.6 2 1 1 3 3 3 1 Dynamin family Miro PF08477.8 KKK11830.1 - 0.011 16.2 0.0 0.099 13.1 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 KKK11830.1 - 0.015 16.1 0.1 0.048 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK11830.1 - 0.017 15.1 0.0 0.061 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KKK11830.1 - 0.023 13.5 0.0 0.039 12.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Arf PF00025.16 KKK11830.1 - 0.059 12.6 0.0 0.54 9.4 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF2570 PF10828.3 KKK11830.1 - 0.1 12.2 0.4 0.35 10.4 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) PI3Ka PF00613.15 KKK11831.1 - 6.5e-60 201.4 0.1 1.1e-59 200.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KKK11831.1 - 4.7e-42 144.0 0.0 1.8e-40 138.9 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KKK11831.1 - 2.3e-27 95.4 0.0 3.9e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 ThiF PF00899.16 KKK11832.1 - 2.5e-35 121.2 0.0 4.3e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 KKK11832.1 - 0.034 14.1 0.4 0.075 13.0 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Glyco_hydro_17 PF00332.13 KKK11832.1 - 0.047 12.7 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 ApbA PF02558.11 KKK11832.1 - 0.11 11.8 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MARVEL PF01284.18 KKK11833.1 - 4.6e-21 75.1 14.6 5.8e-21 74.8 10.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain PepSY_TM_2 PF13703.1 KKK11833.1 - 2.6 8.2 12.9 0.63 10.2 0.3 3.2 2 1 1 3 3 3 0 PepSY-associated TM helix DUF2976 PF11190.3 KKK11833.1 - 5 6.7 6.1 1.1 8.8 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) GMC_oxred_N PF00732.14 KKK11834.1 - 6.2e-31 107.6 0.0 1.3e-30 106.6 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK11834.1 - 4.1e-16 59.5 0.5 6.7e-16 58.8 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KKK11834.1 - 1.8e-11 43.5 1.9 2.2e-05 23.5 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK11834.1 - 7.4e-07 28.3 0.0 0.016 14.0 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KKK11834.1 - 3.2e-06 27.0 0.3 2.2e-05 24.3 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KKK11834.1 - 3.9e-06 25.5 0.0 4.9e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KKK11834.1 - 4.9e-06 26.5 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK11834.1 - 6.6e-06 26.3 0.0 0.097 12.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK11834.1 - 0.00023 21.4 0.1 0.17 12.3 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK11834.1 - 0.0011 18.1 0.0 0.028 13.5 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK11834.1 - 0.0014 17.7 0.1 0.0033 16.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KKK11834.1 - 0.0043 16.1 0.0 0.0095 15.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KKK11834.1 - 0.0099 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KKK11834.1 - 0.027 14.2 0.1 0.086 12.6 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KKK11834.1 - 0.072 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Metallophos PF00149.23 KKK11835.1 - 1.9e-13 50.2 0.1 4.5e-13 49.0 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK11835.1 - 2.2e-07 30.8 0.2 3.5e-07 30.1 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KKK11835.1 - 0.15 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily LCCL PF03815.14 KKK11836.1 - 4.7e-22 77.7 0.0 8.2e-22 77.0 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Spc97_Spc98 PF04130.8 KKK11837.1 - 9.5e-120 400.4 0.0 2.3e-119 399.1 0.0 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family Herpes_pp38 PF04846.8 KKK11838.1 - 0.08 12.2 0.4 0.14 11.4 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein E1-E2_ATPase PF00122.15 KKK11839.1 - 1e-68 230.7 2.3 1e-68 230.7 1.6 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KKK11839.1 - 8e-24 85.2 1.9 3.2e-23 83.2 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK11839.1 - 7.8e-13 49.0 0.0 2.8e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK11839.1 - 1e-09 37.7 0.0 2.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK11839.1 - 0.0016 18.0 0.1 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK11839.1 - 0.0094 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DMA PF03474.9 KKK11839.1 - 0.085 12.7 0.1 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif RRM_1 PF00076.17 KKK11840.1 - 1.1e-43 146.7 0.0 5.3e-21 74.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK11840.1 - 3.2e-33 113.5 0.0 2.8e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK11840.1 - 1.3e-17 63.3 0.0 2e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK11840.1 - 0.025 14.3 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Alg6_Alg8 PF03155.10 KKK11841.1 - 4.6e-133 444.4 15.8 7.9e-86 288.7 5.6 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.8 KKK11842.1 - 5.9e-22 77.4 6.3 7.6e-22 77.0 4.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KKK11842.1 - 0.074 12.8 2.8 0.2 11.4 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUFB10 PF10249.4 KKK11842.1 - 0.097 12.8 0.8 0.11 12.6 0.6 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 YedD PF13987.1 KKK11842.1 - 0.11 12.1 0.2 0.11 12.1 0.2 1.4 2 0 0 2 2 2 0 YedD-like protein Pet191_N PF10203.4 KKK11842.1 - 0.41 10.7 5.4 0.55 10.3 3.7 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 LRR_6 PF13516.1 KKK11843.1 - 2.9e-11 42.2 2.4 0.15 12.2 0.0 7.6 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 KKK11843.1 - 3.6e-08 32.8 5.0 0.021 14.4 0.0 5.4 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KKK11843.1 - 0.00052 19.6 4.4 16 6.0 0.0 6.3 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_7 PF13504.1 KKK11843.1 - 0.022 14.8 1.2 2.5e+02 2.6 0.0 5.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 KKK11843.1 - 0.04 13.6 4.9 1.8 8.4 0.0 4.5 5 1 0 5 5 5 0 Leucine rich repeat Mpp10 PF04006.7 KKK11843.1 - 0.074 11.4 25.2 0.099 10.9 17.4 1.1 1 0 0 1 1 1 0 Mpp10 protein OmpH PF03938.9 KKK11843.1 - 2.2 8.2 11.5 3.9 7.3 7.6 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Nop14 PF04147.7 KKK11843.1 - 2.9 5.6 23.8 4.1 5.1 16.5 1.2 1 0 0 1 1 1 0 Nop14-like family GOLD_2 PF13897.1 KKK11843.1 - 6.7 6.9 7.1 15 5.8 4.9 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Daxx PF03344.10 KKK11843.1 - 7 5.0 23.4 9.4 4.5 16.2 1.1 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 KKK11843.1 - 9.2 4.3 15.5 12 3.9 10.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein TFIIS_M PF07500.9 KKK11844.1 - 8e-27 93.5 1.4 3.5e-26 91.5 0.0 2.3 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KKK11844.1 - 1e-18 66.6 5.9 1.7e-18 65.9 4.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KKK11844.1 - 5.1e-14 51.5 0.3 1e-13 50.5 0.2 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 KKK11844.1 - 0.011 15.1 1.5 0.029 13.7 1.0 1.8 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain RGS PF00615.14 KKK11844.1 - 0.11 12.5 0.3 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Regulator of G protein signaling domain Pectinesterase PF01095.14 KKK11845.1 - 1.7e-25 89.2 0.8 2.5e-20 72.2 0.2 2.1 2 0 0 2 2 2 2 Pectinesterase Fungal_trans PF04082.13 KKK11847.1 - 1.4e-11 43.7 0.4 2.7e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK11847.1 - 6.1e-08 32.4 11.2 1.4e-07 31.3 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KKK11848.1 - 2.6e-69 233.2 0.0 3.2e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 KKK11850.1 - 0.00094 17.8 0.7 0.07 11.7 0.4 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK11851.1 - 2.8e-05 23.9 12.5 4.9e-05 23.1 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3112 PF11309.3 KKK11852.1 - 4e-51 172.9 7.2 2e-46 157.6 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) ELO PF01151.13 KKK11852.1 - 0.067 12.4 1.1 0.14 11.4 0.1 2.1 2 1 0 2 2 2 0 GNS1/SUR4 family OxoDH_E1alpha_N PF12573.3 KKK11852.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal ABC2_membrane_5 PF13346.1 KKK11852.1 - 0.57 9.4 16.8 0.031 13.5 1.8 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein PLAC8 PF04749.12 KKK11852.1 - 0.93 10.0 3.7 3 8.4 0.0 2.7 2 1 0 2 2 2 0 PLAC8 family Ninjurin PF04923.7 KKK11852.1 - 1.3 8.7 5.8 1.7 8.3 0.7 2.7 2 1 0 2 2 2 0 Ninjurin Fungal_trans PF04082.13 KKK11853.1 - 9.2e-16 57.4 0.1 1.7e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK11853.1 - 3.8e-07 29.8 10.1 3.8e-07 29.8 7.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK11854.1 - 2.4e-23 82.4 18.6 4.1e-23 81.6 12.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 KKK11855.1 - 2.9e-47 161.5 0.0 3.7e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Clr5 PF14420.1 KKK11856.1 - 2.7e-05 23.9 0.1 5.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Clr5 domain Dyp_perox PF04261.7 KKK11857.1 - 9e-94 313.7 0.0 1e-93 313.5 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF3224 PF11528.3 KKK11859.1 - 2.5e-06 27.0 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) TPR_12 PF13424.1 KKK11862.1 - 1.6e-09 37.5 2.0 0.04 13.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KKK11862.1 - 5.9e-08 32.2 3.6 1.2e-05 24.8 0.3 3.9 3 1 1 4 4 4 2 TPR repeat AAA_16 PF13191.1 KKK11862.1 - 2.7e-06 27.5 0.1 2.1e-05 24.6 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 KKK11862.1 - 7.9e-05 22.3 0.0 0.00051 19.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain TPR_2 PF07719.12 KKK11862.1 - 0.00051 19.7 10.1 0.0026 17.5 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK11862.1 - 0.0007 19.2 5.2 0.13 12.0 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK11862.1 - 0.001 18.6 0.9 3.3 7.7 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 KKK11862.1 - 0.0017 18.5 0.0 0.013 15.6 0.0 2.6 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.1 KKK11862.1 - 0.0052 17.0 6.0 0.19 12.0 0.1 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat AAA_17 PF13207.1 KKK11862.1 - 0.0089 16.8 0.1 0.066 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain RPN7 PF10602.4 KKK11862.1 - 0.0095 15.3 3.5 0.4 10.0 0.3 3.5 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_1 PF00515.23 KKK11862.1 - 0.014 14.9 6.3 0.021 14.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MNE1 PF13762.1 KKK11862.1 - 0.017 15.2 0.2 3.8 7.5 0.1 3.5 3 1 0 3 3 3 0 Mitochondrial splicing apparatus component TPR_10 PF13374.1 KKK11862.1 - 0.027 14.4 0.5 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK11862.1 - 0.1 13.2 14.2 0.11 13.2 0.0 6.1 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KKK11862.1 - 0.11 12.7 0.7 2.6 8.4 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat adh_short PF00106.20 KKK11863.1 - 5.9e-18 65.3 0.5 1.5e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK11863.1 - 8.9e-12 45.0 0.0 2.8e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KKK11863.1 - 1.4e-05 24.1 0.0 2.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KKK11863.1 - 0.0003 20.3 0.0 0.0022 17.4 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KKK11863.1 - 0.0044 17.1 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Lipoprotein_18 PF06804.6 KKK11863.1 - 0.048 12.4 0.0 0.37 9.5 0.0 1.9 2 0 0 2 2 2 0 NlpB/DapX lipoprotein NAD_binding_4 PF07993.7 KKK11863.1 - 0.093 11.6 0.1 0.67 8.8 0.0 2.2 3 0 0 3 3 3 0 Male sterility protein TLP-20 PF06088.6 KKK11864.1 - 0.13 11.9 4.6 0.16 11.6 3.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) BAF1_ABF1 PF04684.8 KKK11864.1 - 2.3 7.0 11.9 2.4 6.9 8.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MFS_1 PF07690.11 KKK11865.1 - 3.3e-52 177.3 26.2 3.3e-52 177.3 18.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK11865.1 - 4.6e-13 48.5 8.0 4.6e-13 48.5 5.5 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KKK11865.1 - 2.1e-05 22.9 3.4 2.1e-05 22.9 2.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 KKK11865.1 - 0.00011 20.9 4.7 0.00018 20.3 1.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF791) DUF3353 PF11833.3 KKK11865.1 - 0.41 10.0 5.3 1.4 8.3 3.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) MFS_1 PF07690.11 KKK11866.1 - 5.4e-43 147.0 51.3 5.4e-43 147.0 35.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK11866.1 - 2.8e-08 32.7 12.2 2.8e-08 32.7 8.5 3.9 2 1 2 4 4 4 2 Sugar (and other) transporter AA_permease PF00324.16 KKK11867.1 - 1.1e-106 357.0 37.5 1.4e-106 356.7 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK11867.1 - 2.2e-37 128.6 41.7 2.7e-37 128.3 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.8 KKK11867.1 - 0.72 8.1 3.8 1.2 7.4 2.6 1.3 1 0 0 1 1 1 0 Tweety Gp_dh_C PF02800.15 KKK11868.1 - 2.1e-58 196.2 0.0 3.2e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KKK11868.1 - 3.3e-48 163.4 0.1 5.8e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KKK11868.1 - 0.00067 19.5 0.0 0.007 16.2 0.0 2.3 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 KKK11868.1 - 0.0028 16.8 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KKK11869.1 - 5.2e-95 318.6 28.5 6e-95 318.4 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK11869.1 - 1.7e-27 96.0 57.4 9.3e-25 87.0 20.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK11869.1 - 0.0002 19.9 1.8 0.0002 19.9 1.2 3.4 3 1 1 4 4 4 2 MFS/sugar transport protein p450 PF00067.17 KKK11870.1 - 5.2e-65 219.7 0.0 6.1e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Motilin_assoc PF04643.7 KKK11870.1 - 0.1 12.0 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide Abhydrolase_6 PF12697.2 KKK11871.1 - 3.5e-19 69.6 0.2 4.9e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK11871.1 - 8.7e-05 22.1 0.1 0.00023 20.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK11871.1 - 0.00044 20.0 0.0 0.00067 19.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FA_hydroxylase PF04116.8 KKK11873.1 - 1.7e-14 54.1 12.3 1.7e-14 54.1 8.5 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Apq12 PF12716.2 KKK11873.1 - 0.18 11.5 2.8 0.41 10.3 1.9 1.6 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis zf-RING_4 PF14570.1 KKK11902.1 - 3.1e-19 68.2 13.4 5.3e-19 67.5 9.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 KKK11902.1 - 2e-05 24.1 0.0 4.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KKK11902.1 - 3.8e-05 23.2 6.9 7e-05 22.4 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 KKK11902.1 - 0.00046 19.9 5.1 0.00081 19.1 3.5 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 KKK11902.1 - 0.00083 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 KKK11902.1 - 0.006 15.8 1.7 0.006 15.8 1.2 2.1 3 0 0 3 3 3 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 KKK11902.1 - 0.093 12.4 12.7 0.18 11.4 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK11902.1 - 0.63 10.1 11.9 1.1 9.2 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.14 KKK11903.1 - 7.4e-36 122.5 0.0 1.1e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit P5CR_dimer PF14748.1 KKK11909.1 - 1.2e-36 124.8 0.9 1.2e-36 124.8 0.7 1.8 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KKK11909.1 - 5.3e-11 42.8 6.6 2.2e-05 24.7 0.2 2.7 1 1 1 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KKK11909.1 - 5.9e-05 22.8 0.4 5.9e-05 22.8 0.3 2.2 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NMT1_2 PF13379.1 KKK11909.1 - 0.024 14.0 0.0 0.069 12.5 0.0 1.8 2 0 0 2 2 2 0 NMT1-like family ApbA PF02558.11 KKK11909.1 - 0.037 13.4 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KKK11909.1 - 0.12 12.4 0.4 0.28 11.3 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 KKK11911.1 - 2e-48 164.9 17.1 2e-48 164.9 11.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK11911.1 - 3e-12 45.8 6.7 3e-12 45.8 4.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KKK11911.1 - 0.32 9.0 10.8 0.0043 15.2 2.3 1.5 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.15 KKK11911.1 - 0.64 8.0 9.3 0.61 8.0 0.3 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PSDC PF12588.3 KKK11912.1 - 0.041 13.4 0.1 2.1 7.9 0.0 2.3 2 1 0 2 2 2 0 Phophatidylserine decarboxylase Glyco_hydro_31 PF01055.21 KKK11914.1 - 1.2e-81 274.8 8.5 1e-80 271.7 5.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Acetyltransf_1 PF00583.19 KKK11914.1 - 0.0027 17.6 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family peroxidase PF00141.18 KKK11915.1 - 4.3e-89 297.9 0.0 7.2e-47 159.7 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Peptidase_A4 PF01828.12 KKK11916.1 - 1.9e-91 304.7 11.8 2.3e-91 304.5 8.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF1049 PF06305.6 KKK11916.1 - 0.049 13.1 0.1 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Fer4 PF00037.22 KKK11917.1 - 5.5e-14 51.0 16.4 3.1e-08 32.8 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KKK11917.1 - 9.1e-12 45.1 10.8 1.5e-11 44.5 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KKK11917.1 - 1.6e-10 41.5 7.5 5.3e-05 23.8 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KKK11917.1 - 2.6e-10 39.9 23.3 3e-08 33.3 8.8 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KKK11917.1 - 1.3e-09 38.2 11.3 2.6e-09 37.2 7.9 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KKK11917.1 - 5.6e-09 35.7 32.3 1.2e-05 25.0 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_17 PF13534.1 KKK11917.1 - 7.3e-09 35.8 2.1 0.0008 19.6 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 KKK11917.1 - 4.2e-08 33.0 21.0 2.3e-05 24.3 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KKK11917.1 - 1.1e-07 31.2 14.3 0.00058 19.6 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KKK11917.1 - 4.5e-07 29.6 12.6 0.00057 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KKK11917.1 - 6.2e-07 29.0 17.4 0.0012 18.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 KKK11917.1 - 0.0001 22.6 10.4 0.022 15.1 0.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 KKK11917.1 - 0.004 17.6 12.6 0.23 12.0 1.1 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 KKK11917.1 - 0.0091 16.3 15.7 0.3 11.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 KKK11917.1 - 0.018 15.5 17.5 0.04 14.4 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KKK11917.1 - 0.11 12.6 5.7 0.76 9.9 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain SURF6 PF04935.7 KKK11918.1 - 5.5e-51 172.8 24.5 5.5e-51 172.8 17.0 4.7 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 KKK11918.1 - 3.8e-23 81.3 1.0 3.8e-23 81.3 0.7 8.5 7 2 1 8 8 8 1 60S ribosome biogenesis protein Rrp14 PP-binding PF00550.20 KKK11920.1 - 3.2e-10 40.1 0.2 4.7e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KKK11920.1 - 1.4e-06 28.2 0.1 1.8e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_S2 PF00318.15 KKK11921.1 - 1.5e-51 174.5 0.0 2.1e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 Rick_17kDa_Anti PF05433.10 KKK11922.1 - 3.9e-05 23.2 13.1 6.9e-05 22.4 9.1 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 KKK11922.1 - 0.00038 20.0 9.2 0.00085 18.9 6.4 1.7 1 0 0 1 1 1 1 Glycine zipper DUF533 PF04391.7 KKK11922.1 - 0.0033 16.8 3.4 0.0033 16.8 2.4 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF533) DUF1269 PF06897.7 KKK11922.1 - 0.15 12.0 2.9 0.4 10.7 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) Bacteriocin_IIc PF10439.4 KKK11922.1 - 1.5 9.0 10.1 2.6 8.2 7.0 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 KKK11922.1 - 3.4 7.2 17.4 7.7 6.1 11.7 1.8 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 KKK11922.1 - 4.5 6.9 28.3 0.063 12.9 10.9 2.7 2 2 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Transgly_assoc PF04226.8 KKK11922.1 - 6.3 6.9 10.6 9.8 6.3 7.4 1.2 1 0 0 1 1 1 0 Transglycosylase associated protein CDP-OH_P_transf PF01066.16 KKK11923.1 - 6.9e-17 61.6 5.4 1.1e-16 60.9 3.7 1.3 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF1382 PF07131.6 KKK11924.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) UQ_con PF00179.21 KKK11928.1 - 6.6e-40 135.7 0.0 8.2e-40 135.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK11928.1 - 0.097 12.4 0.1 0.42 10.3 0.1 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 KKK11928.1 - 0.12 12.2 1.1 0.26 11.1 0.7 1.6 1 1 0 1 1 1 0 RWD domain TRAP_alpha PF03896.11 KKK11928.1 - 0.24 10.3 4.1 0.39 9.6 2.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ABC_tran PF00005.22 KKK11929.1 - 8.7e-54 181.5 0.0 3.2e-31 108.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK11929.1 - 1.3e-45 156.0 28.7 1.8e-26 93.1 2.7 3.9 4 1 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 KKK11929.1 - 5.6e-08 32.2 0.0 0.0013 18.0 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK11929.1 - 5.1e-07 29.9 9.5 0.042 13.8 0.0 4.5 5 1 1 6 6 4 2 AAA domain AAA_25 PF13481.1 KKK11929.1 - 8.5e-07 28.5 0.0 0.018 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KKK11929.1 - 3.4e-05 24.2 7.4 0.00041 20.7 0.1 3.1 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KKK11929.1 - 0.00028 20.9 0.2 1.2 9.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KKK11929.1 - 0.00029 20.0 0.2 0.19 10.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KKK11929.1 - 0.00039 20.3 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KKK11929.1 - 0.00059 19.3 0.2 1 8.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 KKK11929.1 - 0.0007 19.1 0.5 0.16 11.3 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain Miro PF08477.8 KKK11929.1 - 0.0008 19.8 0.1 2.4 8.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 KKK11929.1 - 0.0017 17.3 0.0 0.083 11.7 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 KKK11929.1 - 0.0021 18.1 1.4 7.3 6.7 0.1 3.5 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KKK11929.1 - 0.0022 18.7 0.3 3.3 8.5 0.1 3.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KKK11929.1 - 0.0026 16.8 4.4 0.16 11.0 0.1 2.5 3 0 0 3 3 2 2 Zeta toxin DUF87 PF01935.12 KKK11929.1 - 0.0036 17.1 2.3 0.029 14.1 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 IstB_IS21 PF01695.12 KKK11929.1 - 0.0049 16.3 0.2 2.2 7.6 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.1 KKK11929.1 - 0.0058 16.9 1.0 7 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KKK11929.1 - 0.0068 16.6 1.0 0.58 10.3 0.1 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 KKK11929.1 - 0.024 14.1 0.2 5.7 6.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 KKK11929.1 - 0.066 12.9 0.1 14 5.3 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KKK11929.1 - 0.1 12.7 0.1 19 5.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KKK11929.1 - 0.14 12.0 0.3 4.3 7.2 0.1 2.9 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 KKK11929.1 - 0.21 10.1 1.9 1.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 KKK11929.1 - 0.27 10.8 2.1 2.3 7.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KKK11929.1 - 0.76 9.4 3.7 0.31 10.6 0.0 2.2 3 0 0 3 3 2 0 Archaeal ATPase Beach PF02138.13 KKK11930.1 - 6.6e-110 366.7 0.1 2.4e-109 364.9 0.0 2.0 2 1 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 KKK11930.1 - 4.9e-13 48.8 0.0 1.3e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KKK11930.1 - 2.7e-09 36.5 0.4 0.002 17.9 0.2 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 KKK11930.1 - 2.8e-07 30.8 0.0 6.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_S8 PF00082.17 KKK11931.1 - 1.6e-56 191.5 8.4 2.3e-56 191.0 5.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KKK11931.1 - 1.2e-17 64.2 0.4 6.2e-17 61.9 0.1 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 Ferritin_2 PF13668.1 KKK11932.1 - 1.1e-09 38.2 0.0 1.6e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain ATXN-1_C PF12547.3 KKK11932.1 - 0.21 11.5 2.3 4.2 7.4 0.0 3.2 3 0 0 3 3 3 0 Capicua transcriptional repressor modulator Tad PF13400.1 KKK11932.1 - 0.58 10.2 4.8 0.3 11.1 0.5 2.4 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF3446 PF11928.3 KKK11932.1 - 4.9 7.4 10.6 0.99 9.6 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Transaldolase PF00923.14 KKK11933.1 - 4e-95 318.2 0.2 4.6e-95 318.0 0.1 1.0 1 0 0 1 1 1 1 Transaldolase Sod_Cu PF00080.15 KKK11934.1 - 6.4e-45 152.7 3.2 7.5e-45 152.5 2.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Chlorovi_GP_rpt PF06598.6 KKK11934.1 - 0.3 10.9 2.9 1 9.2 0.2 2.4 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat SNase PF00565.12 KKK11935.1 - 1e-77 257.3 0.2 9.8e-25 86.9 0.0 5.7 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KKK11935.1 - 5.6e-24 84.3 0.0 1.4e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 KKK11935.1 - 0.00073 18.7 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) zf-H2C2_2 PF13465.1 KKK11946.1 - 2.6e-07 30.5 12.0 9.9e-06 25.5 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK11946.1 - 2.7e-06 27.2 13.9 0.00019 21.5 4.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KKK11946.1 - 0.00041 20.4 3.9 0.00071 19.6 2.7 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KKK11946.1 - 0.0038 17.4 16.8 0.018 15.3 4.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK11946.1 - 0.0043 17.1 4.7 0.058 13.5 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 KKK11946.1 - 0.17 11.6 1.4 0.29 10.9 1.0 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.2 KKK11946.1 - 0.61 10.3 5.3 1.8 8.8 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 KKK11946.1 - 0.9 9.3 9.2 0.34 10.6 1.3 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 KKK11946.1 - 6.3 6.5 8.4 8.9 6.1 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type dCMP_cyt_deam_1 PF00383.17 KKK11947.1 - 2.8e-12 46.1 0.0 1.4e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KKK11947.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Uricase PF01014.13 KKK11949.1 - 1.6e-87 290.6 2.7 5e-49 165.9 0.4 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 KKK11949.1 - 0.04 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Nup96 PF12110.3 KKK11950.1 - 1.2e-100 336.4 0.4 2.3e-100 335.4 0.1 1.5 2 0 0 2 2 2 1 Nuclear protein 96 MFS_1 PF07690.11 KKK11951.1 - 4.4e-50 170.3 28.2 2.1e-42 145.1 15.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK11951.1 - 2.3e-05 23.2 15.9 2.3e-05 23.2 11.1 3.5 3 1 0 3 3 3 3 Sugar (and other) transporter Ribosomal_60s PF00428.14 KKK11951.1 - 5.1 7.5 8.2 1.1 9.6 2.9 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein OATP PF03137.15 KKK11951.1 - 5.9 4.8 10.7 2 6.3 0.3 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Trp_syntA PF00290.15 KKK11955.1 - 3.6e-90 301.0 0.0 5.7e-90 300.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KKK11955.1 - 2.7e-35 122.1 0.3 4.4e-35 121.3 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C2H2 PF00096.21 KKK11982.1 - 6.1e-06 26.2 8.2 1.1e-05 25.4 0.8 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-met PF12874.2 KKK11982.1 - 4e-05 23.6 0.3 9.9e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK11982.1 - 8.2e-05 22.6 0.2 0.0002 21.3 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KKK11982.1 - 0.00019 21.5 3.7 0.0012 19.0 0.6 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK11982.1 - 0.00045 20.3 8.9 0.043 14.1 1.1 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KKK11982.1 - 0.0031 17.3 4.2 0.036 13.9 0.3 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KKK11982.1 - 0.048 13.7 0.3 0.08 13.0 0.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KKK11982.1 - 0.24 11.1 2.8 0.7 9.7 1.9 1.8 1 1 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 KKK11982.1 - 3.6 8.0 6.7 2.7 8.3 0.7 3.1 2 1 1 3 3 3 0 C2H2-type zinc-finger domain BCDHK_Adom3 PF10436.4 KKK11983.1 - 4.8e-47 159.5 0.1 9.5e-47 158.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KKK11983.1 - 2.3e-10 40.1 0.0 1.1e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KKK11983.1 - 0.0025 17.5 0.0 0.8 9.4 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 KKK11983.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPC22 PF04573.7 KKK11984.1 - 3.2e-23 81.8 0.0 9.3e-12 44.5 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit ASD2 PF08687.6 KKK11984.1 - 0.0054 16.1 0.6 0.0064 15.8 0.4 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 NST1 PF13945.1 KKK11984.1 - 0.037 14.1 6.1 0.052 13.6 4.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator SR-25 PF10500.4 KKK11984.1 - 0.14 11.5 15.0 0.24 10.8 10.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tmemb_cc2 PF10267.4 KKK11984.1 - 0.31 9.5 3.8 0.39 9.2 2.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein EMP24_GP25L PF01105.19 KKK11985.1 - 2.7e-46 157.6 1.2 3.1e-46 157.3 0.8 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD USP7_ICP0_bdg PF12436.3 KKK11986.1 - 7.8e-90 300.4 0.0 6.1e-89 297.5 0.0 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KKK11986.1 - 5.5e-69 231.8 0.4 1.6e-67 227.0 0.0 2.8 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 KKK11986.1 - 8.5e-55 185.7 0.3 1.9e-54 184.6 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK11986.1 - 2.1e-32 112.7 0.0 3.7e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KKK11986.1 - 1.9e-09 37.7 0.2 1.1e-08 35.3 0.0 2.4 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 KKK11986.1 - 0.009 15.6 0.8 8.4 6.1 0.1 4.3 3 1 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 KKK11986.1 - 0.033 14.7 0.0 4.7 7.8 0.0 2.9 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD E3_binding PF02817.12 KKK11986.1 - 0.33 10.6 0.8 0.57 9.8 0.0 1.8 2 0 0 2 2 2 0 e3 binding domain DnaJ PF00226.26 KKK11988.1 - 6.5e-26 89.8 1.5 1.2e-25 89.0 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KKK11988.1 - 1.8e-23 82.1 0.3 1.7e-19 69.4 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KKK11988.1 - 8.5e-14 51.3 17.6 1.6e-13 50.4 12.2 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KKK11988.1 - 0.052 13.2 8.9 0.036 13.7 1.4 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 KKK11988.1 - 0.65 9.7 5.7 3.9 7.3 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zf-RING_3 PF14369.1 KKK11988.1 - 1.7 8.6 3.8 27 4.8 0.1 2.9 3 0 0 3 3 3 0 zinc-finger zinc-ribbons_6 PF07191.7 KKK11988.1 - 3.8 7.3 5.6 9.8 6.0 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbons Sulfate_transp PF00916.15 KKK11989.1 - 8.3e-75 251.3 10.2 1.5e-74 250.5 7.0 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KKK11989.1 - 6.9e-32 108.9 3.3 6.9e-32 108.9 2.3 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KKK11989.1 - 4.6e-08 32.4 0.0 9.1e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF457 PF04307.9 KKK11989.1 - 0.004 16.4 3.7 0.016 14.5 2.6 2.1 1 0 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) SNN_transmemb PF09049.5 KKK11989.1 - 1.9 8.2 9.4 0.041 13.5 0.8 2.7 2 0 0 2 2 2 0 Stannin transmembrane URO-D PF01208.12 KKK11990.1 - 5.7e-125 416.7 0.0 6.5e-125 416.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 KKK11990.1 - 0.041 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Phloem filament protein PP1 dCMP_cyt_deam_1 PF00383.17 KKK11991.1 - 4.4e-15 55.1 0.1 6.7e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KKK11991.1 - 0.0091 15.6 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 KKK11991.1 - 0.011 15.5 2.4 0.04 13.7 0.6 2.0 1 1 1 2 2 2 0 Bd3614-like deaminase XOO_2897-deam PF14440.1 KKK11991.1 - 0.013 15.2 0.1 0.057 13.1 0.0 1.9 1 1 1 2 2 2 0 Xanthomonas XOO_2897-like deaminase WD40 PF00400.27 KKK11992.1 - 4.3e-05 23.2 0.2 0.069 13.0 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Biopterin_H PF00351.16 KKK11992.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Ribosomal_L10 PF00466.15 KKK11993.1 - 1.2e-26 92.5 0.3 2.4e-26 91.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KKK11993.1 - 4.5e-22 78.2 4.1 4.5e-22 78.2 2.9 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Sugar_tr PF00083.19 KKK11997.1 - 1.3e-109 366.8 29.2 1.5e-109 366.6 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK11997.1 - 5.9e-23 81.1 33.6 6.9e-17 61.1 3.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KKK11997.1 - 1.9e-05 22.9 5.4 0.004 15.2 0.2 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KKK11998.1 - 2.7e-31 108.5 21.3 2.7e-31 108.5 14.8 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily Pex14_N PF04695.8 KKK11998.1 - 0.002 18.1 1.1 0.035 14.1 0.1 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region UNC-93 PF05978.11 KKK11998.1 - 0.0069 15.8 2.4 0.014 14.9 1.7 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Spt20 PF12090.3 KKK11998.1 - 0.067 12.5 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Spt20 family zf-CCHC PF00098.18 KKK11999.1 - 4.5e-49 162.1 93.2 1.2e-06 28.1 3.0 11.3 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_3 PF13917.1 KKK11999.1 - 1.7e-12 46.8 68.3 0.022 14.5 1.1 10.5 3 3 7 10 10 10 8 Zinc knuckle zf-CCHC_4 PF14392.1 KKK11999.1 - 2e-10 40.1 74.3 0.028 14.1 0.2 11.2 11 0 0 11 11 11 8 Zinc knuckle zf-CCHC_6 PF15288.1 KKK11999.1 - 0.00029 20.4 1.2 0.00029 20.4 0.8 10.0 10 2 1 11 11 11 6 Zinc knuckle zf-CCHC_2 PF13696.1 KKK11999.1 - 0.00053 19.4 39.5 0.0099 15.3 0.1 8.0 6 2 2 8 8 8 3 Zinc knuckle SelR PF01641.13 KKK11999.1 - 7.7 6.2 14.2 0.19 11.4 1.4 3.7 3 1 1 4 4 4 0 SelR domain DHDPS PF00701.17 KKK12000.1 - 0.17 10.4 0.0 0.27 9.7 0.0 1.4 1 1 0 1 1 1 0 Dihydrodipicolinate synthetase family HpcH_HpaI PF03328.9 KKK12001.1 - 1.4e-37 128.7 0.0 7.9e-37 126.2 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KKK12001.1 - 1.3e-12 47.2 0.0 1.5e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF846 PF05832.7 KKK12002.1 - 1.5e-48 164.1 9.9 1.8e-48 163.8 6.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) SNARE_assoc PF09335.6 KKK12003.1 - 1e-10 41.8 3.4 1e-10 41.8 2.3 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein TMEMspv1-c74-12 PF11044.3 KKK12003.1 - 0.006 16.1 0.1 0.018 14.6 0.1 1.8 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein BUD22 PF09073.5 KKK12003.1 - 0.06 12.4 7.6 0.094 11.7 5.3 1.2 1 0 0 1 1 1 0 BUD22 Pox_RNA_Pol_19 PF05320.7 KKK12003.1 - 0.083 12.6 7.7 4.5 6.9 6.5 2.1 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF3186 PF11382.3 KKK12003.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Nucleoplasmin PF03066.10 KKK12003.1 - 0.37 10.3 10.4 0.57 9.6 7.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF3671 PF12420.3 KKK12003.1 - 3.5 7.6 5.0 2.2 8.3 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function Patched PF02460.13 KKK12003.1 - 4.6 5.0 6.0 0.23 9.3 0.5 1.5 2 0 0 2 2 2 0 Patched family Daxx PF03344.10 KKK12003.1 - 9.7 4.5 16.3 14 3.9 11.3 1.1 1 0 0 1 1 1 0 Daxx Family DUF1771 PF08590.5 KKK12004.1 - 6.2e-17 61.3 10.2 1.6e-16 60.0 7.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KKK12004.1 - 1.7e-13 50.5 0.9 1.8e-12 47.2 0.1 3.0 3 0 0 3 3 3 1 Smr domain zf-CCCH PF00642.19 KKK12004.1 - 1.1e-06 28.1 3.0 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Period_C PF12114.3 KKK12005.1 - 1.6 8.2 6.7 1.8 8.1 4.7 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Pyr_redox_2 PF07992.9 KKK12006.1 - 1.7e-25 90.1 0.1 2.1e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK12006.1 - 1.2e-15 57.6 0.0 1.3e-12 47.9 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK12006.1 - 3.4e-10 40.3 0.0 4.2e-05 23.7 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK12006.1 - 0.00019 20.6 0.1 0.00063 18.9 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 KKK12006.1 - 0.00051 20.2 0.0 0.09 13.0 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KKK12006.1 - 0.00082 19.3 0.5 0.03 14.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KKK12006.1 - 0.0019 18.2 0.0 3.1 7.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 KKK12006.1 - 0.0041 16.0 0.0 0.89 8.4 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KKK12006.1 - 0.0087 14.9 3.1 1.5 7.5 0.0 3.5 4 1 1 5 5 5 1 Glucose inhibited division protein A DAO PF01266.19 KKK12006.1 - 0.016 14.1 5.1 1.8 7.4 0.0 3.8 2 2 2 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK12006.1 - 0.037 13.0 0.6 4.5 6.2 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 KKK12006.1 - 0.22 10.3 3.7 0.24 10.1 0.2 2.6 3 1 1 4 4 4 0 FAD binding domain Trp_halogenase PF04820.9 KKK12006.1 - 0.22 10.0 0.2 0.53 8.8 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Peptidase_S8 PF00082.17 KKK12007.1 - 1.7e-52 178.3 1.1 2.6e-52 177.7 0.7 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KKK12007.1 - 5.8e-29 99.7 1.4 1.1e-28 98.8 1.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PX PF00787.19 KKK12008.1 - 5.1e-19 68.1 0.4 1.2e-18 66.9 0.3 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KKK12008.1 - 5.4e-15 55.2 6.7 2.7e-07 30.0 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KKK12008.1 - 0.00074 19.0 4.1 0.0027 17.2 2.9 2.0 1 1 0 1 1 1 1 BAR domain DUF3140 PF11338.3 KKK12008.1 - 0.023 14.8 0.3 0.1 12.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) DUF724 PF05266.9 KKK12008.1 - 0.1 12.2 3.2 6.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.6 KKK12008.1 - 0.2 11.6 1.6 15 5.5 0.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 KKK12008.1 - 0.22 11.2 2.6 0.31 10.7 0.2 2.3 2 1 1 3 3 3 0 Laminin Domain II IncA PF04156.9 KKK12008.1 - 0.36 10.4 1.7 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 KKK12008.1 - 0.55 10.0 3.5 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.7 KKK12008.1 - 1 9.1 4.4 5.8 6.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Amino_oxidase PF01593.19 KKK12009.1 - 7.7e-92 308.7 0.0 2e-91 307.3 0.0 1.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KKK12009.1 - 4.5e-14 52.3 0.1 8.2e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 KKK12009.1 - 9.9e-08 31.8 0.1 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 KKK12009.1 - 0.0011 19.2 0.7 0.0011 19.2 0.5 2.7 1 1 1 2 2 2 1 HMG (high mobility group) box DAO PF01266.19 KKK12009.1 - 0.0061 15.5 0.1 0.031 13.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HMG_box_2 PF09011.5 KKK12009.1 - 0.011 16.1 0.7 0.011 16.1 0.5 2.4 2 1 1 3 3 3 0 HMG-box domain HyaE PF07449.6 KKK12009.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE PhoD PF09423.5 KKK12010.1 - 6.1e-05 21.7 0.0 0.018 13.6 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Gln-synt_C PF00120.19 KKK12011.1 - 1.5e-58 197.9 0.0 1.8e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KKK12011.1 - 3e-20 71.5 0.0 5.2e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SKG6 PF08693.5 KKK12012.1 - 3e-06 26.4 4.9 3e-06 26.4 3.4 3.3 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DcuC PF03606.10 KKK12012.1 - 0.0023 16.2 0.0 0.0035 15.6 0.0 1.2 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier DUF3609 PF12259.3 KKK12012.1 - 0.016 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Rifin_STEVOR PF02009.11 KKK12012.1 - 0.031 13.9 14.6 0.81 9.2 10.1 2.2 1 1 0 1 1 1 0 Rifin/stevor family Gemini_mov PF01708.11 KKK12012.1 - 0.58 9.7 0.0 0.58 9.7 0.0 2.4 2 1 0 2 2 2 0 Geminivirus putative movement protein DUF1510 PF07423.6 KKK12012.1 - 0.78 9.0 0.0 0.78 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Mitofilin PF09731.4 KKK12012.1 - 4 5.9 10.3 5.9 5.4 7.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PCI PF01399.22 KKK12013.1 - 1.8e-21 76.4 0.0 1.2e-20 73.7 0.1 2.3 2 1 0 2 2 2 1 PCI domain DDRGK PF09756.4 KKK12013.1 - 7.2e-05 22.2 0.1 7.2e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 DDRGK domain Prefoldin_2 PF01920.15 KKK12013.1 - 0.046 13.4 2.5 0.083 12.6 0.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit HTH_Crp_2 PF13545.1 KKK12013.1 - 0.054 13.2 0.3 1.3 8.9 0.1 2.9 2 1 1 3 3 3 0 Crp-like helix-turn-helix domain TPR_8 PF13181.1 KKK12013.1 - 0.65 9.9 13.8 9.8 6.2 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK12013.1 - 3.3 8.6 12.8 12 6.8 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KKK12013.1 - 4.9 7.1 21.8 0.91 9.5 2.3 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat adh_short PF00106.20 KKK12014.1 - 1.6e-28 99.6 0.3 2.4e-28 99.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK12014.1 - 4.4e-14 52.8 0.0 6.3e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK12014.1 - 4e-09 36.3 0.2 7.6e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KKK12014.1 - 0.00098 18.3 0.1 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF690 PF05108.8 KKK12014.1 - 0.012 14.0 0.1 0.018 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF690) SWIB PF02201.13 KKK12015.1 - 9e-16 57.3 0.0 1.5e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain WD40 PF00400.27 KKK12016.1 - 1.1e-36 123.3 3.9 4.9e-09 35.7 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 KKK12016.1 - 3.4e-30 103.9 14.3 6e-30 103.1 9.9 1.4 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 KKK12016.1 - 0.00015 21.5 0.3 0.0014 18.3 0.0 2.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KKK12016.1 - 0.0038 15.4 1.3 0.04 12.0 0.0 2.4 2 1 0 2 2 2 1 Nucleoporin Nup120/160 ADH_N PF08240.7 KKK12017.1 - 1.2e-25 89.4 4.2 2.3e-25 88.4 2.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK12017.1 - 1.8e-17 63.0 0.1 4.3e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KKK12017.1 - 8.9e-05 21.7 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.27 KKK12018.1 - 3.1e-44 147.3 8.0 2.2e-10 39.9 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 KKK12018.1 - 6.8e-12 44.9 0.2 1.4e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK12018.1 - 1.4e-05 24.5 0.1 3.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain PQQ PF01011.16 KKK12018.1 - 0.012 15.1 0.1 17 5.1 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_2 PF13360.1 KKK12018.1 - 0.026 13.9 0.4 0.33 10.3 0.3 2.3 1 1 0 1 1 1 0 PQQ-like domain Elongin_A PF06881.6 KKK12018.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PHD PF00628.24 KKK12019.1 - 1.4e-08 34.3 10.0 2.5e-08 33.4 6.9 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KKK12019.1 - 6.3e-06 26.4 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-RING-like PF08746.6 KKK12019.1 - 0.76 9.8 5.9 1.3 9.0 4.1 1.4 1 0 0 1 1 1 0 RING-like domain GFO_IDH_MocA PF01408.17 KKK12020.1 - 3e-08 34.2 0.3 1.4e-07 32.0 0.2 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.17 KKK12021.1 - 1.3e-32 112.5 0.0 4.5e-24 84.5 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 KKK12021.1 - 0.0048 16.1 0.0 0.0083 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DIOX_N PF14226.1 KKK12021.1 - 0.098 13.1 0.1 0.25 11.8 0.0 1.6 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal Pkinase PF00069.20 KKK12035.1 - 1.5e-20 73.4 0.0 9.1e-20 70.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12035.1 - 1.5e-09 37.3 0.1 0.0049 15.9 0.0 3.4 4 0 0 4 4 4 3 Protein tyrosine kinase DHO_dh PF01180.16 KKK12060.1 - 5e-63 212.7 0.1 2.4e-53 181.0 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 KKK12060.1 - 0.00021 20.6 1.3 0.38 9.9 0.1 2.3 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 KKK12060.1 - 0.045 12.6 0.1 0.68 8.7 0.1 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase TIM PF00121.13 KKK12061.1 - 4.2e-43 147.1 0.0 5.2e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 KKK12062.1 - 9.5e-41 138.7 0.0 1.1e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 KKK12062.1 - 0.0051 16.6 0.0 0.0072 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycine-rich SFCGS DUF676 PF05057.9 KKK12065.1 - 2.1e-05 23.9 0.1 5.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KKK12065.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK12065.1 - 0.0011 18.6 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KKK12065.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family ECH PF00378.15 KKK12066.1 - 1e-46 159.0 0.0 1.3e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF883 PF05957.8 KKK12067.1 - 0.014 15.7 7.3 0.015 15.7 2.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 KKK12067.1 - 0.034 14.5 7.8 0.31 11.4 2.4 2.2 1 1 1 2 2 2 0 YtxH-like protein LEA_4 PF02987.11 KKK12067.1 - 0.039 13.8 5.0 0.039 13.8 3.5 3.4 1 1 2 3 3 3 0 Late embryogenesis abundant protein CtnDOT_TraJ PF07863.6 KKK12067.1 - 2.6 8.5 5.0 2.6 8.5 2.5 1.9 1 1 1 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon NB-ARC PF00931.17 KKK12068.1 - 9.5e-13 47.6 0.0 1.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KKK12068.1 - 3e-07 30.6 0.0 6.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KKK12068.1 - 0.00098 19.0 0.1 0.0027 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KKK12068.1 - 0.0014 17.8 0.0 0.0054 15.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 KKK12068.1 - 0.0026 17.7 0.0 0.0068 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain KaiC PF06745.8 KKK12068.1 - 0.0036 16.4 0.1 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_17 PF13207.1 KKK12068.1 - 0.0062 17.3 0.0 0.03 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KKK12068.1 - 0.0073 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RuvB_N PF05496.7 KKK12068.1 - 0.029 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RP-C_C PF11800.3 KKK12068.1 - 0.1 12.2 1.0 0.26 10.9 0.1 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region DnaJ PF00226.26 KKK12069.1 - 3e-08 33.2 0.4 7.2e-08 32.0 0.2 1.7 2 0 0 2 2 2 1 DnaJ domain FHA PF00498.21 KKK12070.1 - 1.1e-11 44.6 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Abhydrolase_3 PF07859.8 KKK12071.1 - 2.2e-40 138.4 0.0 3.5e-39 134.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK12071.1 - 1.3e-06 27.2 0.0 1.1e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK12071.1 - 0.0039 16.9 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pterin_4a PF01329.14 KKK12071.1 - 0.031 14.0 0.2 0.72 9.6 0.1 2.2 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase GatB_N PF02934.10 KKK12072.1 - 2e-100 335.4 0.0 2.9e-100 334.8 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KKK12072.1 - 1.6e-26 92.7 0.1 3.3e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 GatB domain Vitellogenin_N PF01347.17 KKK12072.1 - 0.0018 16.6 0.0 0.0027 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF3602 PF12223.3 KKK12075.1 - 3.4e-19 68.9 15.9 9.3e-14 51.5 2.3 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF2406 PF10295.4 KKK12076.1 - 6.1e-22 77.9 2.9 6.7e-21 74.5 0.0 3.0 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.13 KKK12078.1 - 1.6e-41 139.9 0.4 1.9e-41 139.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KKK12078.1 - 0.0037 17.1 0.1 1.4 8.9 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.4 KKK12078.1 - 0.17 11.6 1.1 1.2 8.9 0.1 2.2 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) G6PD_C PF02781.11 KKK12079.1 - 2.6e-136 453.2 0.0 3.6e-136 452.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KKK12079.1 - 8.7e-64 215.1 0.0 1.5e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_2 PF13347.1 KKK12080.1 - 4e-15 55.1 11.1 4e-15 55.1 7.7 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein DUF1228 PF06779.9 KKK12080.1 - 0.031 14.3 4.4 1.2 9.1 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF2569 PF10754.4 KKK12080.1 - 0.089 13.0 0.2 0.089 13.0 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2569) MFS_1_like PF12832.2 KKK12080.1 - 0.1 12.4 0.0 0.1 12.4 0.0 3.8 3 1 0 3 3 3 0 MFS_1 like family DUF1708 PF08101.6 KKK12081.1 - 2.3e-154 514.2 0.0 3.3e-154 513.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 KKK12081.1 - 0.016 14.8 0.0 0.061 12.9 0.0 1.9 2 0 0 2 2 2 0 RhoGAP domain Pkinase PF00069.20 KKK12082.1 - 3.2e-31 108.4 0.0 5.3e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12082.1 - 7.1e-09 35.1 0.0 0.0016 17.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KKK12082.1 - 0.56 9.8 3.2 3.6 7.2 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family SRF-TF PF00319.13 KKK12083.1 - 4.4e-23 80.2 0.1 6.7e-23 79.6 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MFS_1 PF07690.11 KKK12084.1 - 1.7e-49 168.4 55.3 1.7e-49 168.4 38.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK12084.1 - 2.2e-16 59.2 20.6 1.1e-15 56.9 14.4 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK12084.1 - 2.2e-13 49.5 13.7 2.2e-13 49.5 9.5 3.8 1 1 3 4 4 4 2 Sugar (and other) transporter RrnaAD PF00398.15 KKK12085.1 - 0.00032 19.8 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase ApbA_C PF08546.6 KKK12085.1 - 0.1 12.5 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal HrpB7 PF09486.5 KKK12085.1 - 0.12 12.2 1.8 0.21 11.4 1.2 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Prominin PF05478.6 KKK12085.1 - 0.71 7.3 1.4 0.97 6.8 0.9 1.1 1 0 0 1 1 1 0 Prominin JAB PF01398.16 KKK12086.1 - 3e-15 55.9 0.0 5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KKK12086.1 - 1.6e-09 37.7 0.2 2.8e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KKK12086.1 - 1.1e-05 24.8 0.0 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Methyltransf_23 PF13489.1 KKK12087.1 - 8.9e-07 28.7 0.3 1.4e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain FTHFS PF01268.14 KKK12088.1 - 7.2e-255 846.2 0.0 9.8e-255 845.7 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KKK12088.1 - 3.2e-67 224.6 1.1 7.6e-67 223.3 0.8 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KKK12088.1 - 2.8e-38 130.5 0.9 8e-38 129.0 0.6 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain MBF1 PF08523.5 KKK12089.1 - 8.9e-26 89.7 1.9 1.5e-25 88.9 0.4 1.9 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KKK12089.1 - 2.5e-11 43.2 0.0 3.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KKK12089.1 - 2.1e-05 24.5 0.0 4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KKK12089.1 - 0.00024 21.0 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain WD40 PF00400.27 KKK12090.1 - 1.3e-31 107.3 2.7 9.6e-11 41.1 0.0 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KKK12090.1 - 0.00075 17.7 0.4 0.0012 17.0 0.2 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KKK12090.1 - 0.0026 17.2 1.1 0.024 14.1 0.8 2.2 1 1 0 1 1 1 1 PQQ-like domain Gmad1 PF10647.4 KKK12090.1 - 0.0065 15.8 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Pyr_redox_2 PF07992.9 KKK12090.1 - 0.011 15.5 0.0 4.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Polyketide_cyc2 PF10604.4 KKK12091.1 - 2.5e-07 30.9 10.1 2.6e-06 27.6 7.0 2.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 KKK12091.1 - 0.00024 21.2 0.6 0.001 19.1 0.4 2.0 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.15 KKK12091.1 - 0.0024 17.8 2.0 0.0038 17.2 1.2 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4232 PF14016.1 KKK12091.1 - 0.15 11.7 3.0 0.24 11.0 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) Pkinase PF00069.20 KKK12092.1 - 5.3e-15 55.2 0.0 7.4e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12092.1 - 7.7e-07 28.4 0.0 1.5e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK12092.1 - 0.0018 18.0 0.1 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Iso_dh PF00180.15 KKK12093.1 - 4.9e-71 239.4 0.0 6e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3733 PF12534.3 KKK12094.1 - 0.5 9.6 4.3 0.16 11.2 0.6 2.0 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 Hydrolase_6 PF13344.1 KKK12096.1 - 3.4e-31 107.1 0.0 6.2e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK12096.1 - 7.8e-14 52.5 0.0 1.3e-13 51.8 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK12096.1 - 4.3e-12 45.5 0.0 2.6e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KKK12096.1 - 1.8e-07 31.5 0.1 1.6e-05 25.1 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK12096.1 - 0.056 13.5 0.1 0.46 10.6 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 KKK12096.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Sec20 PF03908.8 KKK12097.1 - 1.2e-16 60.1 1.0 1.2e-16 60.1 0.7 2.3 3 0 0 3 3 2 1 Sec20 AAA PF00004.24 KKK12097.1 - 2.3e-14 53.7 0.0 8.5e-14 51.8 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KKK12097.1 - 1.1e-13 51.1 0.1 8.1e-13 48.3 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KKK12097.1 - 4.1e-10 38.9 0.1 6.1e-08 31.8 0.0 2.3 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 KKK12097.1 - 9.9e-10 38.2 0.0 2.7e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 KKK12097.1 - 2.7e-06 26.6 0.0 7e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KKK12097.1 - 5.1e-05 23.4 0.1 0.00088 19.4 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.1 KKK12097.1 - 5.6e-05 22.8 4.2 0.0011 18.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK12097.1 - 0.00016 21.3 0.0 0.00052 19.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KKK12097.1 - 0.00018 21.4 0.0 0.00048 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KKK12097.1 - 0.00085 18.5 0.0 0.025 13.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KKK12097.1 - 0.0011 18.9 6.2 0.0054 16.7 0.0 3.8 3 1 1 4 4 4 1 AAA ATPase domain AAA_24 PF13479.1 KKK12097.1 - 0.0025 17.4 0.2 0.0099 15.4 0.2 2.0 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK12097.1 - 0.0095 15.4 0.7 0.031 13.7 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 KKK12097.1 - 0.014 15.7 7.1 0.038 14.3 0.0 2.9 2 1 0 2 2 1 0 AAA domain PhoH PF02562.11 KKK12097.1 - 0.024 13.8 2.3 13 4.9 0.0 3.6 4 0 0 4 4 4 0 PhoH-like protein AAA_25 PF13481.1 KKK12097.1 - 0.026 13.9 0.0 0.1 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KKK12097.1 - 0.042 13.5 0.1 0.42 10.3 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KKK12097.1 - 0.055 14.2 0.3 0.42 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain MutS_II PF05188.12 KKK12097.1 - 0.83 9.7 5.0 1.2 9.1 2.5 2.0 1 1 0 1 1 1 0 MutS domain II VMA21 PF09446.5 KKK12098.1 - 7.4e-16 57.8 12.1 9.8e-16 57.4 8.4 1.2 1 0 0 1 1 1 1 VMA21-like domain MS_channel PF00924.13 KKK12098.1 - 0.01 15.2 2.6 0.014 14.7 1.8 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel UPF0104 PF03706.8 KKK12098.1 - 0.012 14.9 0.0 0.014 14.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) NfeD PF01957.13 KKK12098.1 - 0.07 13.2 0.6 0.087 12.9 0.4 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4407 PF14362.1 KKK12098.1 - 0.071 12.0 0.2 0.087 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vpu PF00558.14 KKK12098.1 - 0.12 11.9 0.9 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Vpu protein ABC2_membrane_2 PF12679.2 KKK12098.1 - 6.9 5.4 8.3 8.5 5.1 5.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Sugar_tr PF00083.19 KKK12099.1 - 2.6e-93 313.0 30.6 3e-93 312.8 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK12099.1 - 7.7e-28 97.2 45.6 2.3e-24 85.7 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK12099.1 - 0.00048 18.4 1.6 0.00048 18.4 1.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YrhC PF14143.1 KKK12099.1 - 0.067 13.1 0.1 0.067 13.1 0.1 2.8 4 0 0 4 4 4 0 YrhC-like protein SNF2_N PF00176.18 KKK12100.1 - 3e-62 210.1 0.3 4.7e-62 209.4 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK12100.1 - 3.1e-14 52.5 0.0 9e-14 51.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK12100.1 - 4.9e-07 29.7 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KKK12100.1 - 5.3e-07 29.2 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.2 KKK12100.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif CLP_protease PF00574.18 KKK12101.1 - 3.9e-75 251.5 0.0 4.9e-75 251.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.13 KKK12101.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Peptidase family S49 Mito_carr PF00153.22 KKK12102.1 - 1.3e-48 162.6 6.9 1.8e-17 62.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 KKK12103.1 - 9.6e-05 22.1 0.0 0.48 10.2 0.0 3.1 2 1 0 2 2 2 2 CBS domain Apc4 PF12896.2 KKK12103.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 AIM24 PF01987.12 KKK12106.1 - 1.3e-52 178.3 0.1 1.7e-52 177.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.12 KKK12107.1 - 1.7e-44 150.4 0.1 2.8e-44 149.7 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 KKK12107.1 - 0.11 12.8 0.8 0.39 11.0 0.6 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 KKK12107.1 - 1.2 9.3 7.1 1 9.5 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain adh_short PF00106.20 KKK12108.1 - 3.4e-14 53.1 0.0 5e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK12108.1 - 7.8e-07 28.9 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK12108.1 - 1e-05 25.4 0.0 0.0037 17.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase EF-hand_1 PF00036.27 KKK12109.1 - 1.2e-21 74.2 4.4 6e-07 28.3 0.0 4.7 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KKK12109.1 - 3.2e-20 70.1 1.8 4.8e-06 26.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KKK12109.1 - 8e-20 70.7 0.8 3e-09 36.8 0.5 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KKK12109.1 - 5.5e-17 61.1 1.3 2.8e-08 33.2 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KKK12109.1 - 2.6e-14 51.7 7.8 2.7e-05 23.2 0.2 4.1 4 1 0 4 4 4 3 EF hand EF-hand_10 PF14788.1 KKK12109.1 - 0.083 12.5 0.2 24 4.6 0.0 2.8 3 0 0 3 3 3 0 EF hand RRM_1 PF00076.17 KKK12110.1 - 7.6e-22 76.7 0.0 1e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK12110.1 - 3.1e-15 55.9 0.0 4.2e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK12110.1 - 2.9e-11 43.0 0.0 3.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KKK12110.1 - 0.015 15.1 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif ChaC PF04752.7 KKK12111.1 - 1.3e-43 149.0 0.1 9.6e-43 146.1 0.1 2.0 1 1 0 1 1 1 1 ChaC-like protein SH3_1 PF00018.23 KKK12112.1 - 2.1e-14 52.6 0.0 3.1e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK12112.1 - 7.5e-12 44.6 0.1 1.6e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KKK12112.1 - 9.1e-08 31.4 0.0 1.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.2 KKK12113.1 - 5.4e-52 174.0 8.6 1.3e-18 67.0 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KKK12113.1 - 2.5e-34 115.3 3.3 3.3e-07 29.8 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 KKK12113.1 - 1.2e-28 98.9 2.9 3.7e-09 36.8 0.1 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK12113.1 - 2.4e-28 97.4 2.1 3.4e-08 33.4 0.0 5.8 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK12113.1 - 3.6e-23 79.3 3.8 0.00059 19.8 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat DUF4538 PF15061.1 KKK12114.1 - 6.9 6.0 9.2 18 4.6 5.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4538) DEAD PF00270.24 KKK12115.1 - 8.4e-45 152.2 0.0 1.7e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KKK12115.1 - 9.7e-25 85.8 0.1 2.1e-24 84.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KKK12115.1 - 1.1e-21 76.4 0.0 3e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KKK12115.1 - 0.001 17.9 0.0 0.0026 16.6 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DnaJ PF00226.26 KKK12116.1 - 6.3e-15 54.6 2.6 1.9e-14 53.1 0.5 2.7 3 0 0 3 3 3 1 DnaJ domain Fungal_trans PF04082.13 KKK12117.1 - 1.9e-18 66.2 0.1 4.2e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12117.1 - 2.8e-07 30.3 12.1 5e-07 29.5 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ArfGap PF01412.13 KKK12120.1 - 1.1e-40 138.0 0.3 1.7e-40 137.4 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Meiotic_rec114 PF03525.9 KKK12121.1 - 0.0003 19.4 0.1 0.0003 19.4 0.1 1.9 2 1 0 2 2 2 1 Meiotic recombination protein rec114 ORMDL PF04061.9 KKK12123.1 - 5.4e-61 204.0 4.3 6.4e-61 203.8 3.0 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 KKK12123.1 - 0.26 10.9 2.4 0.28 10.8 1.0 1.6 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) SelR PF01641.13 KKK12124.1 - 2.4e-51 172.6 0.1 3e-51 172.3 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 KKK12124.1 - 0.19 11.7 2.2 0.57 10.2 1.5 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2296 PF10058.4 KKK12124.1 - 0.32 10.7 3.6 2.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DNA_RNApol_7kD PF03604.8 KKK12124.1 - 4.8 6.7 7.2 2.6 7.5 0.1 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit CH PF00307.26 KKK12125.1 - 4.4e-11 42.7 0.0 7.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 KKK12125.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin DUF819 PF05684.7 KKK12126.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF819) PS_Dcarbxylase PF02666.10 KKK12127.1 - 0.071 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase NDUFA12 PF05071.11 KKK12128.1 - 2.4e-13 50.4 0.7 2.4e-13 50.4 0.5 1.9 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Sars6 PF12133.3 KKK12130.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus HECT_2 PF09814.4 KKK12131.1 - 7.6e-84 281.4 0.0 8.7e-84 281.2 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TauD PF02668.11 KKK12132.1 - 1.2e-08 34.9 0.1 7e-07 29.1 0.0 2.0 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KKK12134.1 - 5.1e-25 87.9 20.4 6.2e-25 87.6 14.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Kinesin PF00225.18 KKK12135.1 - 3.9e-57 193.4 0.0 6.3e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain KIAA1430 PF13879.1 KKK12135.1 - 0.024 15.0 5.4 2.3 8.6 1.3 2.8 2 0 0 2 2 2 0 KIAA1430 homologue Shugoshin_N PF07558.6 KKK12135.1 - 0.032 13.9 0.5 0.28 10.9 0.0 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.10 KKK12135.1 - 0.057 13.2 0.5 0.057 13.2 0.3 3.1 3 0 0 3 3 3 0 Basic region leucine zipper DUF837 PF05769.6 KKK12135.1 - 0.11 12.0 8.5 0.8 9.2 5.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF837) KLRAQ PF10205.4 KKK12135.1 - 0.65 10.0 11.9 0.08 12.9 0.6 2.5 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Herpes_BLRF2 PF05812.7 KKK12135.1 - 1.5 8.6 8.7 11 5.8 2.0 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Pox_A_type_inc PF04508.7 KKK12135.1 - 1.7 8.6 6.4 0.49 10.3 0.3 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat NYD-SP28_assoc PF14775.1 KKK12135.1 - 1.9 8.2 4.9 4.8 6.9 1.0 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain DivIC PF04977.10 KKK12135.1 - 2.5 7.6 7.4 15 5.1 1.4 2.9 3 0 0 3 3 3 0 Septum formation initiator RTA1 PF04479.8 KKK12136.1 - 1.1e-16 61.0 3.5 2e-16 60.1 2.4 1.3 1 0 0 1 1 1 1 RTA1 like protein ChAPs PF09295.5 KKK12137.1 - 1.1e-156 521.5 0.0 1.4e-156 521.2 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 KKK12137.1 - 1.7e-07 30.8 0.3 0.0043 16.6 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 KKK12137.1 - 0.00018 21.0 0.0 4.2 7.3 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK12137.1 - 0.00021 20.9 1.3 0.28 11.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK12137.1 - 0.00023 20.6 0.1 3.5 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KKK12137.1 - 0.003 17.6 0.0 0.75 9.9 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KKK12137.1 - 0.014 15.9 7.3 5 8.0 0.0 5.1 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KKK12137.1 - 0.014 15.2 1.4 43 4.1 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK12137.1 - 0.026 15.1 0.3 3.2 8.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK12137.1 - 0.036 14.4 0.6 8.9 6.7 0.0 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KKK12137.1 - 0.077 12.0 3.5 1.2 8.1 0.4 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Antimicrobial_8 PF08103.6 KKK12137.1 - 0.81 9.7 2.0 2.1 8.4 0.3 2.4 2 0 0 2 2 2 0 Uperin family TPR_7 PF13176.1 KKK12137.1 - 1.6 8.6 4.5 56 3.8 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KKK12138.1 - 1.8e-05 24.3 13.0 0.00079 19.0 0.8 5.1 5 0 0 5 5 5 2 TPR repeat TPR_7 PF13176.1 KKK12138.1 - 3.1 7.8 6.2 1.6e+02 2.5 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Choline_transpo PF04515.7 KKK12139.1 - 6.9e-106 353.7 23.7 6.9e-106 353.7 16.4 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter RabGAP-TBC PF00566.13 KKK12139.1 - 9.7e-37 126.5 0.3 2.3e-32 112.1 0.1 2.6 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Fructosamin_kin PF03881.9 KKK12139.1 - 0.024 13.6 0.3 0.089 11.7 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase DUF2370 PF10176.4 KKK12139.1 - 0.046 13.0 0.8 0.18 11.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF4106 PF13388.1 KKK12139.1 - 0.37 9.6 9.6 0.63 8.9 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF4191 PF13829.1 KKK12139.1 - 2.6 7.0 4.9 16 4.5 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) AAA PF00004.24 KKK12140.1 - 6.8e-48 162.2 0.0 3.8e-43 146.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KKK12140.1 - 6.4e-05 22.4 0.0 0.00024 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK12140.1 - 7.8e-05 23.4 0.0 0.0014 19.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KKK12140.1 - 8.9e-05 21.6 0.0 0.00043 19.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 KKK12140.1 - 0.00049 19.0 0.0 0.00081 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 KKK12140.1 - 0.00055 19.9 0.3 0.025 14.5 0.0 3.2 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK12140.1 - 0.00082 19.5 0.0 0.0067 16.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KKK12140.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KKK12140.1 - 0.0022 18.1 0.0 0.013 15.7 0.0 2.3 3 0 0 3 3 2 1 RNA helicase AAA_2 PF07724.9 KKK12140.1 - 0.0032 17.3 0.0 0.0079 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KKK12140.1 - 0.0042 16.8 0.2 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 KKK12140.1 - 0.0058 15.3 0.0 0.0093 14.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KKK12140.1 - 0.023 13.8 0.1 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK12140.1 - 0.024 14.3 0.0 0.076 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 KKK12140.1 - 0.034 13.3 0.0 0.086 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 KKK12140.1 - 0.036 13.1 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 KKK12140.1 - 0.038 14.3 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK12140.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK12140.1 - 0.092 12.6 0.4 0.28 11.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KKK12140.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KKK12140.1 - 0.14 11.6 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KKK12140.1 - 0.19 10.2 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Peptidase_S24 PF00717.18 KKK12141.1 - 7.9e-08 31.8 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.21 KKK12142.1 - 1.7e-41 140.9 0.0 1.9e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK12142.1 - 7.9e-09 35.3 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KKK12142.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 KKK12142.1 - 0.086 12.7 0.2 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 RWD domain AA_permease_2 PF13520.1 KKK12143.1 - 1.6e-43 148.8 56.1 2.3e-43 148.3 38.9 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK12143.1 - 5.2e-14 51.4 43.4 8e-14 50.8 30.1 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4243 PF14027.1 KKK12144.1 - 9.1e-87 291.5 4.4 1.1e-86 291.3 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Fungal_trans PF04082.13 KKK12145.1 - 1.6e-07 30.5 0.7 4e-07 29.1 0.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12145.1 - 0.062 13.2 4.1 0.098 12.5 2.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ERCC4 PF02732.10 KKK12146.1 - 4.7e-33 113.9 0.0 7.4e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain Epimerase PF01370.16 KKK12146.1 - 2.3e-21 76.3 0.0 3.5e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK12146.1 - 3.9e-10 38.9 0.0 6.1e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KKK12146.1 - 1.4e-07 31.6 0.0 4e-06 26.8 0.0 2.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KKK12146.1 - 2.7e-07 29.7 0.0 0.002 17.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KKK12146.1 - 4.5e-06 26.8 0.0 7.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KKK12146.1 - 5.8e-06 25.3 0.0 1.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 KKK12146.1 - 0.0017 18.0 0.0 0.11 12.1 0.0 2.5 1 1 1 2 2 2 1 KR domain Ldh_1_N PF00056.18 KKK12146.1 - 0.0052 16.6 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 KKK12146.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KKK12146.1 - 0.11 11.3 0.0 0.37 9.6 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein zf-GRF PF06839.7 KKK12148.1 - 1.2e-06 28.3 5.1 2.4e-06 27.3 3.6 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF3818 PF12825.2 KKK12149.1 - 2.1e-139 463.9 2.2 3e-139 463.4 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KKK12149.1 - 6.3e-43 145.6 0.4 1.2e-42 144.7 0.3 1.4 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KKK12149.1 - 3.2e-14 52.6 0.7 1.2e-13 50.8 0.1 2.3 2 1 0 2 2 2 1 PX domain DUF2373 PF10180.4 KKK12149.1 - 0.1 12.1 0.6 0.27 10.7 0.4 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) zf-C2H2_4 PF13894.1 KKK12151.1 - 2.9e-06 27.2 12.7 0.00062 19.9 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK12151.1 - 6e-06 26.2 4.0 6e-06 26.2 2.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KKK12151.1 - 1.6e-05 24.9 11.7 0.0071 16.6 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type ATP-synt_DE_N PF02823.11 KKK12154.1 - 2.9e-17 62.2 0.0 5.4e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Glyco_transf_90 PF05686.7 KKK12155.1 - 5.4e-12 45.0 0.4 8e-10 37.9 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 zf-C2H2_4 PF13894.1 KKK12156.1 - 4.3e-07 29.8 11.9 0.091 13.1 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK12156.1 - 0.00039 20.5 7.4 0.01 16.1 0.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Cytochrom_B561 PF03188.11 KKK12157.1 - 2.2e-05 24.2 7.6 0.00077 19.2 7.0 2.2 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 ABA_WDS PF02496.11 KKK12157.1 - 0.46 10.6 3.5 12 6.2 0.1 3.3 4 0 0 4 4 4 0 ABA/WDS induced protein DUF998 PF06197.8 KKK12157.1 - 1.8 7.8 19.7 0.087 12.1 5.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Ribosomal_L29e PF01779.12 KKK12158.1 - 1.8e-09 37.3 0.4 3.6e-09 36.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal L29e protein family PQ-loop PF04193.9 KKK12159.1 - 2.5e-38 129.4 8.8 1.1e-19 69.6 1.1 2.5 2 0 0 2 2 2 2 PQ loop repeat ATG27 PF09451.5 KKK12159.1 - 0.042 13.0 0.6 0.061 12.5 0.4 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 NfeD PF01957.13 KKK12159.1 - 0.047 13.8 0.6 0.68 10.0 0.1 2.4 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2374 PF09574.5 KKK12159.1 - 0.55 9.8 4.3 2.9 7.5 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Fungal_trans PF04082.13 KKK12160.1 - 2.1e-14 53.0 2.0 1.2e-13 50.5 1.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12160.1 - 2.8e-08 33.5 11.8 4.9e-08 32.7 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DBD_Tnp_Mut PF03108.10 KKK12161.1 - 1.5e-13 50.0 0.2 2.7e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase PAT1 PF09770.4 KKK12161.1 - 0.35 9.0 36.1 0.51 8.5 25.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 THOC7 PF05615.8 KKK12162.1 - 8.5e-40 136.2 5.7 8.5e-40 136.2 4.0 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 SSFA2_C PF14723.1 KKK12162.1 - 0.017 14.8 3.7 0.017 14.8 2.6 1.7 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus zf-C4H2 PF10146.4 KKK12162.1 - 0.026 14.5 10.9 0.067 13.2 4.0 2.4 1 1 2 3 3 3 0 Zinc finger-containing protein DUF4600 PF15372.1 KKK12162.1 - 0.089 13.0 9.0 0.19 11.9 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) DUF342 PF03961.8 KKK12162.1 - 0.16 10.3 2.6 0.23 9.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_23 PF13476.1 KKK12162.1 - 0.18 12.1 5.0 0.37 11.0 3.4 1.6 1 0 0 1 1 1 0 AAA domain DUF1843 PF08898.5 KKK12162.1 - 0.87 9.6 4.8 2.3 8.3 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DivIC PF04977.10 KKK12162.1 - 2.6 7.5 8.7 0.6 9.6 2.3 2.7 1 1 1 2 2 2 0 Septum formation initiator FUSC PF04632.7 KKK12162.1 - 3.3 6.0 5.3 3.9 5.8 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_L44 PF00935.14 KKK12163.1 - 2.9e-34 116.9 12.0 5.3e-34 116.0 8.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 FAM217 PF15344.1 KKK12163.1 - 2.7 7.4 7.0 4.3 6.8 4.9 1.2 1 0 0 1 1 1 0 FAM217 family Elongin_A PF06881.6 KKK12164.1 - 1e-31 109.5 0.2 1.8e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Toxin_51 PF15531.1 KKK12164.1 - 0.16 11.7 0.0 4.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Putative toxin 51 Band_7 PF01145.20 KKK12165.1 - 1.3e-13 51.2 0.1 1.3e-13 51.2 0.1 2.3 2 0 0 2 2 2 1 SPFH domain / Band 7 family TBCA PF02970.11 KKK12166.1 - 1.8e-23 82.3 9.2 2.3e-23 82.0 6.4 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Mnd1 PF03962.10 KKK12166.1 - 0.07 12.7 6.7 0.082 12.5 4.6 1.1 1 0 0 1 1 1 0 Mnd1 family GLYCAM-1 PF05242.6 KKK12166.1 - 0.23 11.3 2.9 0.28 11.0 2.0 1.2 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Ead_Ea22 PF13935.1 KKK12166.1 - 0.34 11.2 4.7 0.42 10.9 3.3 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein HABP4_PAI-RBP1 PF04774.10 KKK12166.1 - 1.3 9.5 5.6 0.3 11.6 1.3 1.7 1 1 1 2 2 2 0 Hyaluronan / mRNA binding family IncA PF04156.9 KKK12166.1 - 1.6 8.3 9.6 1.9 8.0 6.7 1.1 1 0 0 1 1 1 0 IncA protein Sugar_tr PF00083.19 KKK12167.1 - 1.7e-80 270.8 18.6 2.3e-80 270.4 12.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK12167.1 - 2.5e-29 102.1 17.1 4.4e-28 98.0 10.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK12167.1 - 0.0048 15.1 1.0 0.0048 15.1 0.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ilm1 PF10311.4 KKK12168.1 - 5.1e-68 227.7 1.5 6.7e-68 227.3 1.0 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.16 KKK12169.1 - 6.2e-33 112.0 10.7 1.6e-10 40.3 0.0 6.5 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KKK12169.1 - 3.9e-26 91.6 0.0 4.6e-18 65.6 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KKK12169.1 - 0.00038 20.4 0.0 0.027 14.4 0.0 3.4 2 1 2 4 4 4 2 Prenyltransferase-like DUF3812 PF12757.2 KKK12170.1 - 2.2e-33 114.9 10.6 2.2e-33 114.9 7.3 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3812) Glyco_hydro_35 PF01301.14 KKK12171.1 - 6.6e-78 262.2 4.8 9.5e-78 261.7 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KKK12171.1 - 6e-57 191.9 2.8 6e-57 191.9 1.9 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KKK12171.1 - 1.3e-49 167.1 1.3 2e-24 85.9 0.5 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KKK12171.1 - 2.2e-26 91.0 0.1 6.1e-26 89.6 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 KKK12171.1 - 1.1e-05 24.7 0.2 0.00017 20.8 0.3 2.3 1 1 1 2 2 2 1 Beta-galactosidase CFEM PF05730.6 KKK12172.1 - 3.8e-14 52.2 15.5 3.8e-14 52.2 10.8 2.3 2 1 0 2 2 2 1 CFEM domain Menin PF05053.8 KKK12172.1 - 0.86 7.6 5.1 1.1 7.3 3.5 1.2 1 0 0 1 1 1 0 Menin DNA_pol_viral_N PF00242.12 KKK12172.1 - 1.1 8.2 7.9 1.1 8.1 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2413 PF10310.4 KKK12172.1 - 1.3 7.7 9.7 1.7 7.3 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TFIIA PF03153.8 KKK12172.1 - 2.6 7.8 7.3 3.1 7.6 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 KKK12172.1 - 3 5.9 11.7 3.6 5.7 8.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Tmemb_cc2 PF10267.4 KKK12172.1 - 3.2 6.2 7.3 3.7 6.0 5.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Pneumo_att_G PF05539.6 KKK12172.1 - 7.1 5.8 33.5 8.9 5.5 23.3 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MFS_1 PF07690.11 KKK12173.1 - 3.9e-34 117.9 19.3 3.9e-34 117.9 13.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK12173.1 - 7e-10 38.0 7.0 7e-10 38.0 4.9 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter Alpha-amylase PF00128.19 KKK12181.1 - 5.8e-18 65.3 1.0 5e-17 62.2 0.7 2.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KKK12181.1 - 1.1e-14 54.5 0.1 1.9e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KKK12181.1 - 2.3e-06 27.7 0.0 5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KKK12181.1 - 5.2e-06 25.9 0.0 1.6e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 VGCC_beta4Aa_N PF12052.3 KKK12181.1 - 0.14 12.0 0.2 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal TPT PF03151.11 KKK12182.1 - 1e-26 93.3 16.2 1e-26 93.3 11.3 2.8 2 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 KKK12182.1 - 0.00042 19.3 24.2 0.012 14.5 16.8 2.2 1 1 0 1 1 1 1 UAA transporter family ECR1_N PF14382.1 KKK12183.1 - 6.9e-10 38.0 0.0 1.7e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KKK12183.1 - 0.0016 18.3 0.1 0.028 14.3 0.1 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 IFRD PF05004.8 KKK12184.1 - 3.9e-28 98.4 2.2 5.1e-28 98.0 1.5 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.2 KKK12184.1 - 2e-05 23.7 0.1 3.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain Corona_nucleoca PF00937.13 KKK12184.1 - 0.043 12.7 7.2 0.091 11.6 5.0 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HEAT PF02985.17 KKK12184.1 - 0.05 13.7 0.0 20 5.5 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat Oxysterol_BP PF01237.13 KKK12185.1 - 8.6e-119 396.1 0.0 1.5e-118 395.3 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KKK12185.1 - 1e-37 128.0 0.5 1.9e-37 127.2 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KKK12185.1 - 4e-06 26.9 0.3 1.5e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KKK12185.1 - 0.0012 19.0 2.2 0.013 15.7 0.4 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain ZZ PF00569.12 KKK12186.1 - 1.2e-20 72.7 49.6 6.7e-07 28.7 5.8 4.3 4 0 0 4 4 4 4 Zinc finger, ZZ type RRM_6 PF14259.1 KKK12187.1 - 3.3e-24 84.6 0.1 6.3e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK12187.1 - 9.9e-22 76.3 0.4 8.8e-13 47.6 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK12187.1 - 4.5e-10 39.2 0.1 5.3e-05 22.9 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK12187.1 - 0.005 16.5 0.1 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Rsc14 PF08586.5 KKK12187.1 - 0.14 12.6 0.2 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit DUF4611 PF15387.1 KKK12187.1 - 0.36 11.0 4.7 2.4 8.3 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Btz PF09405.5 KKK12188.1 - 5.8e-34 116.9 3.3 5.8e-34 116.9 2.3 2.1 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding Ino80_Iec3 PF14612.1 KKK12189.1 - 9.9e-88 294.0 0.0 1.4e-87 293.5 0.0 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Fungal_trans PF04082.13 KKK12204.1 - 1e-29 103.1 1.0 1.2e-29 102.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12204.1 - 4.2e-08 32.9 7.9 4.2e-08 32.9 5.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IMS PF00817.15 KKK12205.1 - 8.7e-42 142.4 0.0 1.5e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KKK12205.1 - 1e-18 67.5 0.0 2.4e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KKK12205.1 - 5.9e-15 55.1 4.9 9.5e-07 28.7 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 KKK12205.1 - 2e-07 30.6 0.1 1e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 KKK12205.1 - 0.00039 20.2 0.0 0.001 18.8 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KKK12205.1 - 0.001 19.1 0.0 0.0032 17.5 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Cdd1 PF11731.3 KKK12205.1 - 0.013 15.3 0.0 0.076 12.9 0.0 2.2 2 0 0 2 2 2 0 Pathogenicity locus HHH_5 PF14520.1 KKK12205.1 - 0.094 12.8 0.0 0.85 9.8 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain adh_short PF00106.20 KKK12206.1 - 1.3e-34 119.5 0.0 1.7e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK12206.1 - 1.4e-15 57.7 0.0 1.7e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK12206.1 - 1e-13 51.3 0.0 1.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KKK12206.1 - 0.00073 18.5 0.1 0.0015 17.4 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KKK12206.1 - 0.0022 17.4 0.0 0.0044 16.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KKK12206.1 - 0.0076 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KKK12206.1 - 0.046 13.5 0.1 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KKK12206.1 - 0.13 12.2 0.2 0.32 10.9 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding GATA PF00320.22 KKK12207.1 - 1.9e-30 103.8 17.5 4.8e-16 57.7 4.0 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KKK12207.1 - 1.3e-05 24.4 3.1 0.0066 15.7 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KKK12207.1 - 0.007 15.5 8.4 0.34 10.1 0.5 2.9 2 1 0 2 2 2 2 zinc-ribbon domain Auto_anti-p27 PF06677.7 KKK12207.1 - 0.017 14.8 4.4 0.2 11.4 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.12 KKK12207.1 - 0.051 13.2 3.2 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.5 KKK12207.1 - 0.06 13.3 2.7 1.3 9.0 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 KKK12207.1 - 0.44 10.4 14.8 6.3e+02 0.3 10.1 3.2 1 1 0 1 1 1 0 Double zinc ribbon ArfGap PF01412.13 KKK12207.1 - 0.53 10.0 4.4 0.81 9.4 0.1 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Amidohydro_1 PF01979.15 KKK12208.1 - 6.9e-38 131.1 0.0 9e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KKK12208.1 - 8.2e-12 45.0 0.1 1.4e-07 31.1 0.0 2.2 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KKK12208.1 - 1.2e-07 32.0 0.2 0.0016 18.5 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KKK12208.1 - 4e-06 26.5 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KKK12208.1 - 0.00043 19.3 0.0 0.0029 16.5 0.0 2.0 1 1 1 2 2 2 1 Adenosine/AMP deaminase MFS_1 PF07690.11 KKK12210.1 - 1.1e-32 113.1 31.9 4.9e-32 111.0 22.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK12210.1 - 6.6e-10 37.8 8.2 7.7e-10 37.5 5.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.11 KKK12210.1 - 1.2 8.6 12.2 0.21 11.0 5.6 2.0 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 Hexokinase_2 PF03727.11 KKK12211.1 - 1.5e-72 243.7 0.0 2e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KKK12211.1 - 1.8e-63 213.5 0.0 2.6e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Adaptin_N PF01602.15 KKK12230.1 - 1.1e-34 119.6 0.2 1.3e-34 119.4 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF1160 PF06648.6 KKK12230.1 - 0.031 14.0 0.6 0.052 13.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1160) PAPS_reduct PF01507.14 KKK12270.1 - 4.5e-27 94.9 0.0 3.2e-25 88.9 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.17 KKK12271.1 - 4.8e-23 80.5 0.2 9.7e-11 41.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK12271.1 - 2.1e-15 56.4 0.0 8.1e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK12271.1 - 0.015 15.1 1.7 2.1 8.2 0.1 3.0 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FliG_N PF14842.1 KKK12271.1 - 0.22 11.6 0.2 0.41 10.7 0.2 1.3 1 0 0 1 1 1 0 FliG N-terminal domain NAD_binding_11 PF14833.1 KKK12272.1 - 8e-33 113.1 0.0 1.4e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KKK12272.1 - 2.1e-27 95.9 0.9 1.5e-26 93.1 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase TGS PF02824.16 KKK12272.1 - 0.067 13.0 0.1 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 TGS domain F420_oxidored PF03807.12 KKK12272.1 - 0.16 12.4 0.6 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF202 PF02656.10 KKK12273.1 - 1.6e-25 89.0 1.4 1.6e-25 89.0 1.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.10 KKK12274.1 - 1e-111 372.9 0.0 1.2e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ank_2 PF12796.2 KKK12279.1 - 3.3e-25 88.2 0.1 5.6e-16 58.6 0.2 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ribosomal_L7Ae PF01248.21 KKK12279.1 - 3.8e-25 87.2 0.6 8.2e-25 86.1 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ank PF00023.25 KKK12279.1 - 7e-21 72.9 0.3 2e-07 30.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KKK12279.1 - 8.6e-19 67.1 1.3 4.3e-07 29.9 0.0 4.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK12279.1 - 3e-15 56.2 0.0 0.0015 18.9 0.0 3.5 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK12279.1 - 7.4e-13 47.3 0.0 0.00019 21.3 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat MR_MLE_C PF13378.1 KKK12280.1 - 5.6e-33 113.2 0.0 9.7e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KKK12280.1 - 9.8e-18 64.2 0.0 2.1e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KKK12280.1 - 5.6e-09 36.3 0.0 1.4e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Vac_ImportDeg PF09783.4 KKK12281.1 - 1.7e-48 164.4 0.6 9.7e-48 161.9 0.2 2.0 2 0 0 2 2 2 1 Vacuolar import and degradation protein PXA PF02194.10 KKK12282.1 - 7.7e-45 152.7 0.1 1.2e-44 152.1 0.1 1.3 1 0 0 1 1 1 1 PXA domain IU_nuc_hydro PF01156.14 KKK12283.1 - 8.7e-92 307.6 0.0 1e-91 307.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Ribosomal_S7e PF01251.13 KKK12287.1 - 2.5e-84 281.5 0.2 3e-84 281.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.8 KKK12288.1 - 1e-136 456.5 0.6 1.8e-91 307.3 0.4 2.2 2 0 0 2 2 2 2 Dynactin p62 family DUF1510 PF07423.6 KKK12288.1 - 0.054 12.8 7.1 0.13 11.5 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 KKK12288.1 - 0.2 9.5 6.8 0.32 8.7 4.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FdhE PF04216.7 KKK12288.1 - 0.25 10.9 6.6 0.54 9.9 4.6 1.5 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF2162 PF09930.4 KKK12288.1 - 0.28 10.3 0.4 0.51 9.4 0.2 1.3 1 0 0 1 1 1 0 Predicted transporter (DUF2162) BUD22 PF09073.5 KKK12288.1 - 0.37 9.8 9.6 0.66 8.9 6.7 1.3 1 0 0 1 1 1 0 BUD22 CobT PF06213.7 KKK12288.1 - 0.81 8.7 14.4 1.5 7.9 10.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 KKK12288.1 - 1.8 6.3 18.7 2.9 5.6 13.0 1.2 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KKK12288.1 - 2.5 7.0 7.9 5 6.0 5.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4611 PF15387.1 KKK12288.1 - 4.5 7.4 16.4 0.6 10.2 7.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) E1-E2_ATPase PF00122.15 KKK12289.1 - 1.5e-59 200.8 0.3 3.5e-59 199.6 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK12289.1 - 3.9e-46 156.8 10.2 3.9e-46 156.8 7.1 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK12289.1 - 3.1e-27 96.3 0.0 8e-27 95.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK12289.1 - 7.4e-18 64.2 0.0 1.5e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK12289.1 - 7.2e-15 55.6 0.0 1.6e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK12289.1 - 8.2e-08 31.5 0.8 8.5e-07 28.3 0.1 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK12289.1 - 8.5e-05 22.2 0.0 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 KKK12289.1 - 9.2 6.2 9.9 0.2 11.5 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3325) K_oxygenase PF13434.1 KKK12290.1 - 5.4e-15 55.1 0.0 2.3e-10 39.9 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KKK12290.1 - 7.3e-12 45.7 0.0 7.3e-05 22.9 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK12290.1 - 1.1e-05 25.2 0.1 0.053 13.2 0.0 3.1 3 1 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KKK12290.1 - 0.00013 21.1 0.1 0.0023 17.0 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK12290.1 - 0.0002 21.2 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK12290.1 - 0.00054 19.9 0.8 0.052 13.5 0.4 3.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK12290.1 - 0.0013 17.6 0.0 5.4 5.8 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KKK12290.1 - 0.002 18.2 0.0 0.25 11.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KKK12290.1 - 0.015 14.2 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 KKK12290.1 - 0.017 15.4 0.0 3.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KKK12290.1 - 0.031 13.1 0.3 0.4 9.4 0.0 2.5 2 1 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.9 KKK12290.1 - 0.17 10.3 0.0 0.79 8.1 0.0 2.0 3 0 0 3 3 3 0 HI0933-like protein SR-25 PF10500.4 KKK12290.1 - 0.39 10.1 7.6 0.65 9.4 5.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Methyltransf_11 PF08241.7 KKK12291.1 - 3e-08 34.0 0.0 6.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK12291.1 - 8e-07 29.4 0.0 1.8e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK12291.1 - 1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK12291.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain P16-Arc PF04699.9 KKK12292.1 - 2.9e-59 199.4 0.0 3.4e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) HMG_CoA_synt_C PF08540.5 KKK12293.1 - 2e-104 349.0 0.7 2.9e-104 348.5 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KKK12293.1 - 2.8e-94 313.5 0.1 4.7e-94 312.8 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Oxysterol_BP PF01237.13 KKK12321.1 - 2.9e-87 292.4 0.1 4.4e-87 291.8 0.1 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein RSN1_TM PF13967.1 KKK12323.1 - 5.3e-41 139.8 2.2 6.6e-41 139.4 1.5 1.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF221 PF02714.10 KKK12324.1 - 2.4e-98 328.9 21.2 3e-98 328.6 14.7 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4463 PF14703.1 KKK12324.1 - 1e-18 67.5 0.1 3.3e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Dockerin_1 PF00404.13 KKK12324.1 - 0.087 12.5 0.2 0.087 12.5 0.1 2.5 2 0 0 2 2 2 0 Dockerin type I repeat LRR19-TM PF15176.1 KKK12324.1 - 2 8.1 4.0 1.1 8.9 0.3 2.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain F_bP_aldolase PF01116.15 KKK12325.1 - 2.4e-97 325.4 0.0 2.8e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF4078 PF13300.1 KKK12327.1 - 4e-29 100.5 16.1 4e-29 100.5 11.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) CENP-H PF05837.7 KKK12328.1 - 7e-35 119.4 4.9 7e-35 119.4 3.4 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) DUF2599 PF10783.4 KKK12328.1 - 0.048 14.3 0.3 0.11 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2599) DUF4332 PF14229.1 KKK12328.1 - 0.11 12.5 4.9 0.11 12.5 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4332) DivIC PF04977.10 KKK12328.1 - 0.51 9.8 15.5 1.3 8.5 0.5 3.3 3 0 0 3 3 3 0 Septum formation initiator TBPIP PF07106.8 KKK12328.1 - 1.2 8.6 9.1 0.069 12.6 0.8 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HMG_box PF00505.14 KKK12329.1 - 5.1e-26 90.7 1.1 7.3e-26 90.2 0.8 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KKK12329.1 - 4.1e-20 71.9 1.6 6.3e-20 71.3 1.1 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KKK12329.1 - 0.0022 17.7 0.9 0.0044 16.7 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 KKK12329.1 - 0.012 15.8 0.2 0.037 14.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) Homoserine_dh PF00742.14 KKK12330.1 - 1e-51 175.1 0.0 1.3e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KKK12330.1 - 1.7e-12 47.7 0.0 3.6e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK12330.1 - 0.099 13.0 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3445 PF11927.3 KKK12331.1 - 2.7e-23 82.6 0.0 4.5e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PNP_UDP_1 PF01048.15 KKK12332.1 - 4e-08 32.5 1.2 1.7e-07 30.4 0.9 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S19 PF00203.16 KKK12333.1 - 1.5e-18 66.1 0.0 2e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 AMP-binding PF00501.23 KKK12334.1 - 9.8e-50 169.1 0.1 1.3e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK12334.1 - 0.1 13.5 0.0 0.28 12.1 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Beta-lactamase PF00144.19 KKK12335.1 - 3.4e-29 101.9 1.1 3.3e-28 98.6 0.8 2.0 1 1 0 1 1 1 1 Beta-lactamase FAD_binding_3 PF01494.14 KKK12336.1 - 1.5e-09 37.4 0.1 5.9e-06 25.5 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KKK12336.1 - 5.7e-05 22.1 0.0 9e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK12336.1 - 7.8e-05 22.5 0.1 0.0055 16.4 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KKK12336.1 - 0.0004 20.3 0.0 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK12336.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK12336.1 - 0.093 11.6 0.0 1 8.2 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein DOG1 PF14144.1 KKK12336.1 - 0.42 10.6 1.7 0.57 10.2 0.1 2.1 2 1 0 2 2 2 0 Seed dormancy control DUF4243 PF14027.1 KKK12337.1 - 1.4e-84 284.3 0.3 1.8e-84 283.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 KKK12337.1 - 5.5e-13 49.3 0.0 9.9e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KKK12337.1 - 0.00048 19.4 0.0 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KKK12337.1 - 0.005 15.5 0.5 0.0072 15.0 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK12337.1 - 0.024 14.0 0.0 0.062 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KKK12337.1 - 0.078 13.2 0.0 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KKK12337.1 - 0.099 11.5 0.0 0.2 10.5 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein GST_C PF00043.20 KKK12338.1 - 1.4e-08 34.6 0.0 2.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK12338.1 - 1.8e-08 34.1 0.3 3e-08 33.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK12338.1 - 2.7e-06 27.7 0.1 4.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK12338.1 - 9.5e-06 25.7 0.0 2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KKK12338.1 - 0.015 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Rieske PF00355.21 KKK12338.1 - 0.034 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain TRF PF08558.5 KKK12339.1 - 3.9e-92 307.9 2.3 6e-92 307.3 1.6 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 KKK12339.1 - 1.6e-05 24.8 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF844 PF05815.6 KKK12339.1 - 0.68 8.7 7.7 1.2 7.8 5.4 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) TFIID_30kDa PF03540.8 KKK12340.1 - 2.5e-24 84.8 0.1 3.8e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit GP38 PF05268.6 KKK12340.1 - 0.012 15.1 9.5 0.016 14.6 6.6 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Dicty_CAR PF05462.6 KKK12350.1 - 6.5e-14 51.5 18.6 4.7e-13 48.6 8.3 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 KKK12350.1 - 6.2e-12 45.1 8.7 9.8e-12 44.4 6.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 KKK12350.1 - 5e-07 29.4 13.5 5e-07 29.4 9.4 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 KKK12350.1 - 0.00084 18.5 3.5 0.00084 18.5 2.4 1.8 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx Transaldolase PF00923.14 KKK12351.1 - 8.9e-19 67.6 0.0 9.5e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Transaldolase PQ-loop PF04193.9 KKK12352.1 - 7.9e-40 134.2 17.6 7.9e-21 73.3 0.9 3.1 3 0 0 3 3 3 2 PQ loop repeat TspO_MBR PF03073.10 KKK12352.1 - 0.045 13.2 1.9 1.9 7.9 0.0 2.9 2 1 1 3 3 3 0 TspO/MBR family SGS PF05002.10 KKK12353.1 - 1.7e-27 94.9 1.4 1.7e-27 94.9 1.0 1.8 2 0 0 2 2 2 1 SGS domain TPR_11 PF13414.1 KKK12353.1 - 2.6e-06 26.9 0.3 5e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 TPR repeat CS PF04969.11 KKK12353.1 - 8.5e-06 26.2 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.12 KKK12353.1 - 0.0014 18.3 0.3 1.7 8.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK12353.1 - 0.0019 17.7 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KKK12353.1 - 0.0057 17.2 3.6 0.4 11.4 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Dicty_REP PF05086.7 KKK12353.1 - 0.15 9.7 4.4 0.2 9.4 3.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 KKK12354.1 - 2.8e-75 252.8 0.0 3.7e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12354.1 - 9e-37 126.5 0.0 1.4e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SIR2 PF02146.12 KKK12354.1 - 4.7e-30 104.6 0.0 7.3e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Kinase-like PF14531.1 KKK12354.1 - 0.001 18.1 0.0 0.0021 17.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK12354.1 - 0.016 14.2 0.1 0.016 14.2 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3716 PF12511.3 KKK12355.1 - 7.8e-17 60.6 6.5 1.2e-16 60.0 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Nucleoplasmin PF03066.10 KKK12355.1 - 0.00023 20.6 7.3 0.058 12.9 0.1 2.2 2 0 0 2 2 2 2 Nucleoplasmin Myc_N PF01056.13 KKK12355.1 - 0.0087 15.2 9.7 0.091 11.9 1.6 2.3 2 0 0 2 2 2 2 Myc amino-terminal region HCMV_UL139 PF12507.3 KKK12355.1 - 0.021 14.9 0.0 1.9 8.6 0.0 2.3 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Prothymosin PF03247.9 KKK12355.1 - 0.17 12.0 27.0 0.46 10.6 4.7 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.5 KKK12355.1 - 0.26 11.5 0.2 0.26 11.5 0.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BSP_II PF05432.6 KKK12355.1 - 0.52 9.5 20.2 0.14 11.3 3.2 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Mak16 PF04874.9 KKK12355.1 - 0.57 10.2 19.5 0.29 11.2 1.9 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region PBP1_TM PF14812.1 KKK12355.1 - 0.74 10.1 9.0 0.67 10.3 0.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PI3K_1B_p101 PF10486.4 KKK12355.1 - 0.81 7.1 6.3 1 6.8 3.9 1.4 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3682 PF12446.3 KKK12355.1 - 1.7 8.9 15.2 5.4 7.3 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Radial_spoke PF04712.7 KKK12355.1 - 5.1 5.7 14.1 0.57 8.8 0.5 2.0 2 0 0 2 2 2 0 Radial spokehead-like protein Prenyltrans PF00432.16 KKK12356.1 - 4e-32 109.4 11.4 3.1e-11 42.6 0.2 5.2 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KKK12356.1 - 7.1e-28 96.7 0.1 5.4e-17 61.7 0.2 5.5 3 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 KKK12356.1 - 1.7e-27 96.0 0.6 3.6e-16 59.5 0.2 5.0 4 1 1 5 5 5 3 Prenyltransferase-like Pec_lyase PF09492.5 KKK12356.1 - 1.5e-08 34.1 5.2 0.5 9.4 0.0 5.9 3 3 1 6 6 6 3 Pectic acid lyase TSGP1 PF07771.6 KKK12356.1 - 0.029 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 DUF3469 PF11952.3 KKK12356.1 - 0.031 13.9 0.1 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) Mago-bind PF09282.5 KKK12356.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Mago binding TP6A_N PF04406.9 KKK12357.1 - 9e-17 60.5 0.0 1.6e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase UQ_con PF00179.21 KKK12358.1 - 4.4e-51 171.9 0.0 5e-51 171.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KKK12358.1 - 0.11 12.3 0.2 0.19 11.6 0.1 1.8 1 1 0 1 1 1 0 RWD domain Ribosomal_L27 PF01016.14 KKK12359.1 - 5.2e-29 99.8 0.0 9.1e-29 99.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein tRNA_int_endo PF01974.12 KKK12360.1 - 8.7e-22 76.7 0.1 2.4e-21 75.3 0.1 1.8 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KKK12360.1 - 3.5e-07 29.6 0.0 0.0042 16.6 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Nop10p PF04135.7 KKK12361.1 - 1.9e-23 81.9 0.3 2.2e-23 81.6 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PrgI PF12666.2 KKK12362.1 - 5.2 7.2 8.5 13 6.0 1.5 2.6 2 0 0 2 2 2 0 PrgI family protein NOB1_Zn_bind PF08772.6 KKK12363.1 - 3.1e-33 113.4 4.3 5.6e-33 112.6 3.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 KKK12363.1 - 0.044 13.6 0.8 0.1 12.4 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.6 KKK12363.1 - 0.51 9.9 4.5 0.14 11.6 0.3 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain AF1Q PF15017.1 KKK12363.1 - 1.5 8.7 15.6 14 5.7 10.8 2.4 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator RR_TM4-6 PF06459.7 KKK12363.1 - 3.6 7.4 10.2 5.4 6.8 7.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Scramblase PF03803.10 KKK12364.1 - 5e-54 182.6 1.0 3.9e-29 101.3 0.0 3.1 2 1 0 2 2 2 2 Scramblase Ribosomal_S18 PF01084.15 KKK12364.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S18 Rad9_Rad53_bind PF08605.5 KKK12365.1 - 5.1e-32 110.4 0.0 7.6e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 KKK12365.1 - 7.7e-05 22.7 0.0 0.0013 18.8 0.0 2.8 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Las1 PF04031.8 KKK12366.1 - 4.1e-46 156.4 0.0 6.7e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 KKK12366.1 - 1.2e-27 96.8 0.9 7.8e-27 94.1 0.6 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK12366.1 - 0.00031 20.3 0.2 0.00071 19.1 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 KKK12366.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_S24 PF00717.18 KKK12367.1 - 2e-05 24.1 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like S-antigen PF05756.6 KKK12368.1 - 0.034 14.1 0.2 0.051 13.5 0.2 1.2 1 0 0 1 1 1 0 S-antigen protein SURF2 PF05477.6 KKK12368.1 - 0.37 9.8 3.3 0.61 9.1 2.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Na_Ca_ex PF01699.19 KKK12369.1 - 6e-45 152.2 37.8 1.9e-23 82.6 7.9 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cnd2 PF05786.9 KKK12370.1 - 2.8e-272 905.5 0.5 3.2e-272 905.3 0.3 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 MARVEL PF01284.18 KKK12371.1 - 0.00014 21.7 5.1 0.0054 16.5 2.6 2.3 2 0 0 2 2 2 1 Membrane-associating domain DUF1191 PF06697.7 KKK12371.1 - 0.017 13.9 0.3 0.97 8.1 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1191) DUF981 PF06168.6 KKK12371.1 - 0.06 13.1 1.5 0.093 12.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2371 PF10177.4 KKK12371.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) SPC25 PF06703.6 KKK12371.1 - 0.16 11.5 1.1 0.36 10.3 0.8 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ndc1_Nup PF09531.5 KKK12371.1 - 0.17 10.2 6.0 0.35 9.2 4.2 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PEN-2 PF10251.4 KKK12371.1 - 0.25 11.5 6.8 0.2 11.9 2.7 2.1 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF2254 PF10011.4 KKK12371.1 - 0.28 9.6 1.5 0.8 8.1 0.9 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Tic20 PF09685.5 KKK12371.1 - 0.57 10.1 8.1 0.038 13.9 0.7 2.1 1 1 0 2 2 2 0 Tic20-like protein DUF1772 PF08592.6 KKK12371.1 - 0.67 9.6 4.3 0.45 10.2 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4381 PF14316.1 KKK12371.1 - 1.2 9.2 3.7 9.9 6.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF202 PF02656.10 KKK12371.1 - 1.4 9.1 15.6 14 5.9 5.9 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Ribosomal_S19 PF00203.16 KKK12380.1 - 1.8e-35 120.4 0.3 2.7e-35 119.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 KKK12380.1 - 0.074 13.1 0.5 0.49 10.4 0.0 1.9 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain SET PF00856.23 KKK12381.1 - 2e-12 47.7 0.0 6.3e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KKK12381.1 - 1.5e-08 34.3 8.8 4.2e-08 32.9 6.2 1.7 1 1 0 1 1 1 1 MYND finger CPSase_L_D2 PF02786.12 KKK12382.1 - 4e-107 356.2 0.0 1.6e-83 279.1 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KKK12382.1 - 1.7e-41 140.8 0.0 3.8e-41 139.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KKK12382.1 - 6.6e-38 130.2 0.4 9.3e-22 77.6 0.0 2.6 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 KKK12382.1 - 2.4e-36 124.1 0.0 6.4e-17 61.6 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KKK12382.1 - 5.5e-26 91.0 0.0 2.6e-10 39.5 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KKK12382.1 - 1.7e-17 63.2 0.0 7.8e-08 31.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KKK12382.1 - 2e-16 59.9 0.1 1.4e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KKK12382.1 - 1.9e-07 30.7 0.0 0.0024 17.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 KKK12382.1 - 0.00016 20.9 0.0 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KKK12382.1 - 0.00075 19.1 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF3439 PF11921.3 KKK12385.1 - 3.8 7.2 18.5 1.1 8.9 2.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SPT2 PF08243.6 KKK12386.1 - 6.5e-06 26.4 8.6 6.5e-06 26.4 5.9 2.2 2 0 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.14 KKK12387.1 - 2.9e-28 98.0 14.9 4.1e-28 97.5 10.3 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 KKK12387.1 - 0.098 10.8 2.2 0.11 10.6 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) EGF_CA PF07645.10 KKK12388.1 - 0.00033 20.5 7.6 0.00033 20.5 5.3 2.0 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.22 KKK12388.1 - 0.00058 19.7 5.2 0.0019 18.1 3.6 2.0 1 1 0 1 1 1 1 EGF-like domain EGF_3 PF12947.2 KKK12388.1 - 0.0028 17.5 5.6 0.0028 17.5 3.9 2.3 2 1 0 2 2 2 1 EGF domain cEGF PF12662.2 KKK12388.1 - 0.0089 15.6 0.3 0.0089 15.6 0.2 2.4 2 0 0 2 2 2 1 Complement Clr-like EGF-like CYTL1 PF15153.1 KKK12388.1 - 0.43 10.2 2.1 2 8.1 0.3 2.1 1 1 1 2 2 2 0 Cytokine-like protein 1 FXa_inhibition PF14670.1 KKK12388.1 - 1.5 9.0 15.1 0.4 10.8 6.8 2.7 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site Carb_kinase PF01256.12 KKK12389.1 - 3.3e-53 180.4 0.4 3.7e-52 177.0 0.3 2.0 1 1 0 1 1 1 1 Carbohydrate kinase MCM PF00493.18 KKK12390.1 - 5.4e-137 456.0 0.2 1e-135 451.8 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KKK12390.1 - 4.8e-29 101.3 0.2 1.2e-28 100.0 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KKK12390.1 - 5.9e-07 28.8 0.0 5.4e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK12390.1 - 3.9e-06 26.6 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK12390.1 - 0.012 15.2 0.0 0.066 12.8 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fungal_trans PF04082.13 KKK12391.1 - 1.6e-29 102.5 3.3 2.1e-29 102.1 0.4 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12391.1 - 5.3e-09 35.8 11.4 1.2e-08 34.6 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 KKK12391.1 - 0.0085 15.7 6.6 0.015 14.9 4.6 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper AMP-binding PF00501.23 KKK12392.1 - 4.3e-93 311.9 0.0 5.1e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK12392.1 - 4.1e-05 24.4 0.1 0.00014 22.6 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA PF00004.24 KKK12393.1 - 4.3e-54 182.2 0.0 2.7e-43 147.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KKK12393.1 - 3.8e-29 100.5 0.3 8.2e-29 99.4 0.2 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KKK12393.1 - 8e-08 32.4 6.5 0.00026 21.0 0.0 4.0 3 1 1 4 4 4 2 AAA ATPase domain AAA_19 PF13245.1 KKK12393.1 - 1.5e-06 27.8 0.2 0.0034 17.0 0.0 3.6 3 0 0 3 3 3 1 Part of AAA domain AAA_2 PF07724.9 KKK12393.1 - 2.2e-06 27.6 0.0 0.067 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KKK12393.1 - 2.8e-06 27.0 4.5 0.0017 18.0 0.0 4.0 4 0 0 4 4 4 1 NACHT domain AAA_17 PF13207.1 KKK12393.1 - 1.4e-05 25.9 3.5 0.23 12.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_14 PF13173.1 KKK12393.1 - 2.9e-05 23.9 0.0 0.21 11.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KKK12393.1 - 8.8e-05 22.6 5.7 0.36 10.9 0.0 4.7 3 2 0 3 3 3 2 AAA domain RuvB_N PF05496.7 KKK12393.1 - 0.00015 20.8 0.0 0.0075 15.3 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KKK12393.1 - 0.00017 21.6 0.3 7.5 6.7 0.0 4.1 4 0 0 4 4 4 0 RNA helicase Zeta_toxin PF06414.7 KKK12393.1 - 0.00042 19.4 0.1 0.45 9.5 0.0 2.6 3 0 0 3 3 2 2 Zeta toxin IstB_IS21 PF01695.12 KKK12393.1 - 0.00042 19.7 3.9 0.094 12.1 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 KKK12393.1 - 0.00043 20.0 0.1 0.79 9.4 0.0 3.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KKK12393.1 - 0.00049 20.4 3.5 0.04 14.2 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 KKK12393.1 - 0.00085 19.2 0.0 0.18 11.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 KKK12393.1 - 0.0033 17.3 0.0 1.4 8.8 0.0 3.2 3 0 0 3 3 3 1 Cytidylate kinase-like family TIP49 PF06068.8 KKK12393.1 - 0.0037 16.0 0.0 0.96 8.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus AAA_28 PF13521.1 KKK12393.1 - 0.0082 16.1 0.0 5.7 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KKK12393.1 - 0.011 15.4 1.7 7.8 6.1 0.0 4.1 3 2 1 4 4 4 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 KKK12393.1 - 0.013 15.5 0.0 3.3 7.7 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KKK12393.1 - 0.014 14.5 1.5 0.16 11.1 0.1 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SKI PF01202.17 KKK12393.1 - 0.015 15.1 0.0 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase DUF2075 PF09848.4 KKK12393.1 - 0.019 13.9 0.6 1.4 7.7 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KKK12393.1 - 0.02 13.7 0.9 0.69 8.7 0.1 3.2 4 0 0 4 4 4 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 KKK12393.1 - 0.03 13.8 0.0 0.33 10.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 KKK12393.1 - 0.035 13.5 0.1 4.7 6.6 0.0 3.3 4 0 0 4 4 4 0 Sigma-54 interaction domain KaiC PF06745.8 KKK12393.1 - 0.037 13.1 3.0 1.1 8.3 0.1 3.0 3 0 0 3 3 3 0 KaiC UPF0079 PF02367.12 KKK12393.1 - 0.053 13.1 1.2 1.3 8.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 KKK12393.1 - 0.066 12.9 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 NTPase KAP_NTPase PF07693.9 KKK12393.1 - 0.13 11.2 0.4 2.9 6.8 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain PhoH PF02562.11 KKK12393.1 - 0.2 10.8 1.7 19 4.3 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.22 KKK12393.1 - 0.51 10.6 4.5 20 5.5 0.0 3.7 4 0 0 4 4 4 0 ABC transporter AAA_25 PF13481.1 KKK12393.1 - 0.73 9.2 9.3 3.4 7.0 0.1 4.5 3 2 2 5 5 4 0 AAA domain cobW PF02492.14 KKK12393.1 - 3.9 6.8 6.4 8.3 5.8 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Mito_carr PF00153.22 KKK12417.1 - 6.7e-42 141.1 1.6 4.6e-20 71.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sod_Fe_C PF02777.13 KKK12418.1 - 1.4e-13 50.5 0.5 2.1e-07 30.7 0.8 2.2 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KKK12418.1 - 0.028 14.6 0.1 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain FMN_dh PF01070.13 KKK12419.1 - 1.2e-104 350.0 0.1 2.2e-104 349.1 0.1 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KKK12419.1 - 1.1e-21 76.4 0.0 4.5e-21 74.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KKK12419.1 - 2.3e-06 26.7 0.0 0.00027 19.9 0.0 2.4 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KKK12419.1 - 2.3e-06 26.7 0.0 3.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ATP11 PF06644.6 KKK12419.1 - 0.014 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein His_biosynth PF00977.16 KKK12419.1 - 0.015 14.5 0.0 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 KKK12419.1 - 0.053 12.6 0.2 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase HlyIII PF03006.15 KKK12420.1 - 1.9e-57 194.2 21.6 2.3e-57 193.9 15.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related FimP PF09766.4 KKK12421.1 - 7.4e-28 97.6 15.4 9e-28 97.3 10.7 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 KKK12421.1 - 6.5e-05 22.8 14.5 0.017 15.0 0.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) Cob_adeno_trans PF01923.13 KKK12421.1 - 0.0091 15.8 5.7 0.026 14.2 0.1 2.1 2 0 0 2 2 2 1 Cobalamin adenosyltransferase DUF972 PF06156.8 KKK12421.1 - 0.013 15.8 7.2 1.1 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CwfJ_C_1 PF04677.10 KKK12421.1 - 0.1 12.2 1.2 0.43 10.2 0.3 2.2 1 1 2 3 3 3 0 Protein similar to CwfJ C-terminus 1 Flagellin_N PF00669.15 KKK12421.1 - 0.18 11.5 2.4 0.19 11.5 0.3 1.8 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Cortex-I_coil PF09304.5 KKK12421.1 - 0.19 11.8 12.1 0.78 9.8 0.4 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil RNase_E_G PF10150.4 KKK12421.1 - 0.49 9.5 5.3 0.98 8.5 1.8 2.0 2 0 0 2 2 2 0 Ribonuclease E/G family DUF3349 PF11829.3 KKK12421.1 - 0.78 10.1 3.0 12 6.4 0.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3349) K-box PF01486.12 KKK12421.1 - 2.1 8.2 14.4 3.8 7.3 7.3 2.9 1 1 2 3 3 3 0 K-box region DUF3450 PF11932.3 KKK12421.1 - 4.6 6.4 10.9 0.26 10.5 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FUSC PF04632.7 KKK12421.1 - 5.1 5.4 6.0 7.4 4.8 4.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bap31 PF05529.7 KKK12421.1 - 5.8 6.3 7.7 23 4.3 0.1 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like APG6 PF04111.7 KKK12421.1 - 6.3 5.7 15.6 1.1 8.1 0.4 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 DUF4140 PF13600.1 KKK12421.1 - 7.1 7.1 8.8 4.8 7.6 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PIG-S PF10510.4 KKK12422.1 - 4.7e-182 606.2 0.1 5.5e-182 606.0 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DAD PF02109.11 KKK12423.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 DAD family Macoilin PF09726.4 KKK12423.1 - 1.9 6.6 7.5 2.2 6.4 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Fungal_trans PF04082.13 KKK12424.1 - 3.5e-22 78.5 0.1 1.3e-21 76.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Polyketide_cyc PF03364.15 KKK12424.1 - 4.2e-21 75.3 0.0 1e-20 74.0 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KKK12424.1 - 0.0005 20.2 0.2 0.0075 16.4 0.1 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Epimerase PF01370.16 KKK12425.1 - 1.1e-23 83.9 0.0 1.4e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK12425.1 - 2.7e-20 72.2 0.0 3.4e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KKK12425.1 - 1.3e-18 67.6 0.0 3.2e-18 66.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KKK12425.1 - 3.6e-11 42.4 0.0 4.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KKK12425.1 - 1.6e-07 30.8 0.0 5.6e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KKK12425.1 - 0.00015 20.7 0.0 0.00023 20.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KKK12425.1 - 0.0034 17.3 0.0 0.0088 15.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK12425.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 KR domain Fe-ADH PF00465.14 KKK12426.1 - 1.3e-33 116.1 3.5 1.9e-33 115.6 2.4 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fungal_trans PF04082.13 KKK12426.1 - 3e-15 55.8 0.5 4.5e-15 55.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fe-ADH_2 PF13685.1 KKK12426.1 - 2.8e-11 43.1 0.6 1.8e-10 40.5 0.2 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Zn_clus PF00172.13 KKK12426.1 - 1.1e-06 28.4 9.2 1.9e-06 27.6 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK12427.1 - 2.9e-28 98.4 0.0 4.4e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.18 KKK12428.1 - 5.3e-07 29.6 0.0 8.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK12428.1 - 4.6e-05 23.0 0.0 8.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KKK12428.1 - 0.0031 16.7 0.0 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 KKK12428.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) UCH PF00443.24 KKK12429.1 - 6.3e-50 169.7 0.0 9.9e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK12429.1 - 1.5e-18 67.3 0.0 2e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ERG4_ERG24 PF01222.12 KKK12430.1 - 4.2e-139 463.7 20.2 5.4e-139 463.4 14.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DLH PF01738.13 KKK12430.1 - 2.5e-29 102.1 0.0 4.6e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family zf-C3HC4_2 PF13923.1 KKK12430.1 - 1.5e-08 34.5 8.3 3.5e-08 33.3 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK12430.1 - 2.8e-07 30.0 5.0 6.2e-07 28.9 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK12430.1 - 3.3e-07 29.8 7.2 6.9e-07 28.8 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK12430.1 - 7e-07 28.9 6.9 1.5e-06 27.9 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain Abhydrolase_5 PF12695.2 KKK12430.1 - 1.5e-06 27.9 0.0 3.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-C3HC4_4 PF15227.1 KKK12430.1 - 6.8e-06 25.8 5.4 3.4e-05 23.6 4.0 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KKK12430.1 - 2.9e-05 23.7 5.0 6.8e-05 22.5 3.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KKK12430.1 - 0.0032 17.1 4.1 0.0045 16.6 2.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger BAAT_C PF08840.6 KKK12430.1 - 0.0063 16.2 0.1 1.7 8.2 0.0 2.5 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KKK12430.1 - 0.054 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 KKK12430.1 - 0.32 10.3 0.0 0.53 9.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chs3p PF12271.3 KKK12431.1 - 1.4e-109 365.6 5.2 1.5e-109 365.4 3.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF4149 PF13664.1 KKK12431.1 - 0.0076 16.2 1.2 0.0076 16.2 0.8 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4149) DUF202 PF02656.10 KKK12431.1 - 0.97 9.6 0.0 0.97 9.6 0.0 4.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Gemini_mov PF01708.11 KKK12431.1 - 3.7 7.1 9.1 6.3 6.4 0.1 3.3 3 0 0 3 3 3 0 Geminivirus putative movement protein Aminotran_1_2 PF00155.16 KKK12433.1 - 3.2e-42 144.7 0.0 3.9e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KKK12433.1 - 7.7e-09 34.7 0.0 1.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KKK12433.1 - 5e-07 28.3 0.0 7.3e-07 27.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KKK12433.1 - 6.9e-07 28.7 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KKK12433.1 - 0.019 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 KKK12433.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.3 1 1 0 1 1 1 0 Allinase AMP-binding PF00501.23 KKK12434.1 - 4.8e-66 222.8 0.0 2e-65 220.8 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK12434.1 - 3e-09 37.7 0.1 6e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Autoind_bind PF03472.10 KKK12434.1 - 0.023 13.9 0.0 0.047 12.9 0.0 1.5 1 0 0 1 1 1 0 Autoinducer binding domain APH PF01636.18 KKK12435.1 - 2.8e-08 33.7 0.0 1.1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family dCMP_cyt_deam_1 PF00383.17 KKK12436.1 - 3.8e-05 23.2 0.0 0.038 13.6 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.6 KKK12437.1 - 1.6e-30 106.4 0.0 3.1e-30 105.5 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KKK12437.1 - 4.4e-05 23.0 0.0 6.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3636 PF12331.3 KKK12438.1 - 3.6e-64 214.8 0.0 7.8e-64 213.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) IncA PF04156.9 KKK12438.1 - 1.2 8.7 6.9 2.1 7.8 4.8 1.3 1 0 0 1 1 1 0 IncA protein S4 PF01479.20 KKK12439.1 - 2.2e-15 55.8 0.0 3.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF722 PF05263.6 KKK12439.1 - 0.012 15.7 1.0 0.027 14.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF722) S4_2 PF13275.1 KKK12439.1 - 0.027 14.0 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 S4 domain HBS1_N PF08938.5 KKK12439.1 - 0.83 9.8 6.1 4 7.6 0.2 2.7 3 0 0 3 3 3 0 HBS1 N-terminus CTP_transf_1 PF01148.15 KKK12440.1 - 1.8e-81 273.6 27.7 2.2e-81 273.3 19.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SelP_N PF04592.9 KKK12441.1 - 1.9 7.8 28.4 0.26 10.6 15.1 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Zip PF02535.17 KKK12441.1 - 3.7 6.4 21.9 0.54 9.2 11.4 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Cyclin_N PF00134.18 KKK12442.1 - 1.2e-12 47.4 0.2 1.3e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Arm PF00514.18 KKK12443.1 - 2.7e-19 68.2 3.7 0.00049 19.8 0.0 8.9 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KKK12443.1 - 1.3e-05 24.8 5.1 3.7 7.8 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 KKK12443.1 - 0.00011 22.4 1.2 0.56 10.5 0.1 4.6 4 0 0 4 4 4 2 HEAT repeats Arm_2 PF04826.8 KKK12443.1 - 0.14 11.2 0.0 6.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Armadillo-like Aldo_ket_red PF00248.16 KKK12444.1 - 1.3e-58 198.0 0.0 1.5e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.2 KKK12445.1 - 4.6e-06 26.8 0.0 0.0079 16.5 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KKK12445.1 - 0.00092 18.9 0.3 1.6 8.6 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 KKK12445.1 - 0.0033 17.8 0.1 2.9 8.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK12445.1 - 0.0099 16.1 0.4 2.1 8.7 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK12445.1 - 0.1 12.9 0.4 10 6.7 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat CorA PF01544.13 KKK12447.1 - 4.7e-10 38.9 5.7 1.8e-09 37.0 1.0 2.2 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Gal4_dimer PF03902.8 KKK12447.1 - 0.17 11.8 1.1 0.46 10.4 0.1 2.3 2 0 0 2 2 2 0 Gal4-like dimerisation domain Cauli_VI PF01693.11 KKK12449.1 - 3e-34 116.7 11.6 3.1e-18 65.4 0.4 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KKK12449.1 - 1e-29 103.5 0.0 1.6e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.16 KKK12450.1 - 4.2e-42 144.0 19.4 5.5e-42 143.6 13.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HEAT_2 PF13646.1 KKK12451.1 - 1.4e-05 25.2 2.2 0.24 11.6 0.0 4.3 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.17 KKK12451.1 - 0.013 15.4 2.8 2.5 8.3 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 KKK12451.1 - 0.034 14.6 0.7 0.034 14.6 0.5 3.5 5 0 0 5 5 5 0 HEAT-like repeat Glyco_hydro_35 PF01301.14 KKK12451.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DNA_ligase_A_M PF01068.16 KKK12452.1 - 1.8e-50 171.0 0.9 1.9e-48 164.5 0.6 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KKK12452.1 - 6.4e-42 143.3 0.3 4.2e-41 140.7 0.2 2.3 1 1 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KKK12452.1 - 3.2e-27 94.7 0.0 1.2e-26 92.8 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region eIF-5_eIF-2B PF01873.12 KKK12453.1 - 6.6e-39 132.4 0.0 1.1e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KKK12453.1 - 1.6e-26 92.0 0.9 3.6e-26 90.9 0.6 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NOA36 PF06524.7 KKK12453.1 - 0.033 13.4 6.7 0.063 12.5 4.6 1.4 1 0 0 1 1 1 0 NOA36 protein DUF221 PF02714.10 KKK12454.1 - 9.2e-105 350.0 30.2 9.2e-105 350.0 20.9 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KKK12454.1 - 2e-44 150.9 0.3 2e-44 150.9 0.2 3.4 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KKK12454.1 - 7.2e-14 51.4 0.0 1.7e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KKK12454.1 - 8.5e-12 45.4 9.8 1.2e-05 25.7 0.0 3.3 3 1 0 3 3 3 2 Domain of unknown function (DUF4463) GP41 PF00517.12 KKK12454.1 - 0.012 15.2 3.1 0.069 12.7 2.2 2.3 1 1 0 1 1 1 0 Retroviral envelope protein MCM PF00493.18 KKK12455.1 - 1.6e-140 467.6 0.0 2.3e-140 467.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family VTC PF09359.5 KKK12455.1 - 3.8e-99 331.2 0.0 6.8e-99 330.4 0.0 1.4 1 0 0 1 1 1 1 VTC domain MCM_N PF14551.1 KKK12455.1 - 1.3e-24 87.0 0.0 7.2e-24 84.6 0.0 2.4 1 0 0 1 1 1 1 MCM N-terminal domain SPX PF03105.14 KKK12455.1 - 2.6e-24 86.4 10.7 1.5e-22 80.6 4.3 3.6 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 KKK12455.1 - 6e-10 39.2 4.6 6e-10 39.2 3.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Mg_chelatase PF01078.16 KKK12455.1 - 1.4e-05 24.3 0.0 0.00027 20.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK12455.1 - 4e-05 23.3 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK12455.1 - 0.0028 17.2 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF999 PF06198.6 KKK12455.1 - 1.1 8.9 4.5 17 5.2 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF999) Band_7 PF01145.20 KKK12456.1 - 1.4e-23 83.7 2.4 1.9e-23 83.3 1.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ank_2 PF12796.2 KKK12457.1 - 6.5e-07 29.6 0.2 0.0071 16.6 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK12457.1 - 0.043 14.3 0.0 17 6.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF3534 PF12053.3 KKK12457.1 - 0.085 12.7 2.1 5.6 6.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3534) DUF2360 PF10152.4 KKK12457.1 - 1.9 8.7 6.3 3.2 8.0 0.4 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Lyase_aromatic PF00221.14 KKK12458.1 - 1.9e-164 547.5 3.8 2.4e-164 547.2 2.6 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase CSTF2_hinge PF14327.1 KKK12459.1 - 1e-30 105.6 2.5 1e-30 105.6 1.8 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KKK12459.1 - 1.9e-19 69.0 0.0 3.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK12459.1 - 3.3e-16 59.0 0.0 5.9e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KKK12459.1 - 5.3e-16 57.6 13.9 5.3e-16 57.6 9.6 2.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KKK12459.1 - 2e-07 30.7 0.0 3.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 KKK12459.1 - 0.044 13.2 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 DUF2523 PF10734.4 KKK12459.1 - 0.12 12.6 0.2 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) RrnaAD PF00398.15 KKK12459.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase 2Fe-2S_thioredx PF01257.14 KKK12460.1 - 6.9e-26 90.5 0.1 8.4e-26 90.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin HSP9_HSP12 PF04119.7 KKK12460.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Heat shock protein 9/12 SNF2_N PF00176.18 KKK12461.1 - 1.2e-23 83.3 0.3 3.5e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KKK12461.1 - 1.5e-17 63.7 0.0 3.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 KKK12461.1 - 0.00013 21.7 0.2 0.00034 20.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KKK12461.1 - 0.0042 16.7 6.8 0.0042 16.7 4.7 3.0 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KKK12461.1 - 0.74 9.9 17.7 0.14 12.2 3.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK12461.1 - 8.6 6.1 18.9 0.86 9.3 3.7 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Utp14 PF04615.8 KKK12470.1 - 0.23 9.5 60.1 0.3 9.1 41.7 1.0 1 0 0 1 1 1 0 Utp14 protein ERG2_Sigma1R PF04622.7 KKK12472.1 - 6.3e-70 234.8 0.1 2.3e-69 232.9 0.1 1.8 1 1 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ATP_bind_3 PF01171.15 KKK12472.1 - 1.5e-18 66.9 0.0 2.8e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 KKK12472.1 - 0.0015 17.9 1.2 0.0015 17.9 0.8 2.3 3 0 0 3 3 3 1 RecR protein DUF2392 PF10288.4 KKK12472.1 - 0.0091 16.3 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Glyco_hydro_12 PF01670.11 KKK12473.1 - 6.4e-36 123.4 2.1 9.1e-36 122.9 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 APH PF01636.18 KKK12474.1 - 3.7e-07 30.1 0.0 1.3e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK12474.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RasGEF PF00617.14 KKK12475.1 - 7.4e-45 152.9 0.4 2.2e-44 151.4 0.1 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KKK12475.1 - 1.8e-14 53.6 0.2 4.6e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Complex1_LYR_2 PF13233.1 KKK12475.1 - 4e-13 49.7 0.3 3.4e-12 46.7 0.0 2.6 3 0 0 3 3 3 1 Complex1_LYR-like Miro PF08477.8 KKK12475.1 - 7.8e-08 32.8 0.0 2.3e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Nfu_N PF08712.6 KKK12476.1 - 1.9e-29 101.1 0.0 5.3e-29 99.6 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KKK12476.1 - 2.5e-22 78.4 0.1 4.3e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain zf-HIT PF04438.11 KKK12477.1 - 2.7e-09 36.5 7.5 4.3e-09 35.8 5.2 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.19 KKK12477.1 - 1.3 9.0 8.3 2.3 8.1 5.8 1.4 1 0 0 1 1 1 0 B-box zinc finger Ribosomal_L15e PF00827.12 KKK12478.1 - 5.3e-90 300.0 12.2 6.1e-90 299.8 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.7 KKK12479.1 - 1.5e-30 104.9 1.3 2.9e-30 104.0 0.9 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 KKK12479.1 - 0.26 9.1 0.2 0.38 8.5 0.2 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein ADH_N PF08240.7 KKK12480.1 - 4.5e-36 122.9 2.3 5.4e-35 119.4 1.8 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK12480.1 - 4.7e-15 55.2 0.0 7.6e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 KKK12480.1 - 0.0027 17.9 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.1 KKK12480.1 - 0.0042 17.9 0.0 0.0079 17.0 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KKK12480.1 - 0.012 14.7 0.4 0.018 14.0 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Gp_dh_N PF00044.19 KKK12480.1 - 0.046 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2318 PF10080.4 KKK12480.1 - 0.093 12.5 0.4 5.9 6.7 0.1 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) XdhC_C PF13478.1 KKK12480.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain HECT PF00632.20 KKK12481.1 - 1.9e-55 188.2 0.0 4.9e-54 183.6 0.0 2.7 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 KKK12481.1 - 0.29 10.9 1.2 0.59 9.9 0.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_8 PF13523.1 KKK12482.1 - 8e-51 171.9 0.0 1.3e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK12482.1 - 2.2e-05 24.6 0.0 5.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain OCD_Mu_crystall PF02423.10 KKK12483.1 - 1.4e-12 47.0 0.0 9.1e-11 41.0 0.0 3.0 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KKK12483.1 - 1.4e-06 28.4 0.0 4.2e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 KKK12483.1 - 0.013 16.0 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Nucleic_acid_bd PF13820.1 KKK12483.1 - 0.097 12.2 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 Putative nucleic acid-binding region Cyclin_N PF00134.18 KKK12484.1 - 1.1e-11 44.3 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KKK12484.1 - 2.7e-10 40.8 0.0 7.2e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Cyclin FRG1 PF06229.7 KKK12485.1 - 4.6e-11 42.5 0.0 7.9e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 FRG1-like family Reg_prop PF07494.6 KKK12485.1 - 0.11 12.6 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Two component regulator propeller DGF-1_C PF11040.3 KKK12485.1 - 0.11 12.3 0.7 0.2 11.5 0.2 1.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DSBA PF01323.15 KKK12487.1 - 4.2e-13 49.2 0.0 4.9e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF2854 PF11016.3 KKK12487.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Glyco_hydro_18 PF00704.23 KKK12489.1 - 6.1e-48 164.0 0.2 6.2e-47 160.7 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KKK12489.1 - 1.6e-07 31.1 21.3 3e-07 30.3 14.8 1.4 1 0 0 1 1 1 1 Chitin recognition protein LytR_C PF13399.1 KKK12489.1 - 0.025 14.9 0.1 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator DinB_2 PF12867.2 KKK12490.1 - 0.015 15.6 0.7 0.34 11.2 0.1 2.3 2 0 0 2 2 2 0 DinB superfamily SLT_L PF14718.1 KKK12490.1 - 0.27 11.0 0.2 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain DUF3328 PF11807.3 KKK12491.1 - 8.1e-30 104.1 2.2 1.1e-29 103.6 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_20 PF00728.17 KKK12492.1 - 9.3e-97 324.3 0.8 1.2e-96 323.9 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KKK12492.1 - 6.3e-23 81.8 0.0 1.3e-22 80.7 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KKK12492.1 - 5e-06 27.0 0.0 9.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF3824 PF12868.2 KKK12502.1 - 1.2e-35 123.4 33.3 1.2e-35 123.4 23.1 7.2 5 1 3 8 8 8 3 Domain of unknwon function (DUF3824) Cupin_8 PF13621.1 KKK12503.1 - 1.1e-34 120.0 0.1 1.9e-34 119.2 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KKK12503.1 - 1.2e-07 31.2 0.0 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 KKK12503.1 - 0.00069 19.8 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KKK12503.1 - 0.068 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Cupin domain MFS_1 PF07690.11 KKK12504.1 - 4.3e-37 127.6 14.6 8.2e-29 100.4 0.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK12504.1 - 3.4e-10 39.1 5.3 6.3e-10 38.2 3.7 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KKK12504.1 - 1.3e-05 23.7 3.3 1.3e-05 23.7 2.3 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein GTP1_OBG PF01018.17 KKK12505.1 - 1.4e-40 138.5 4.0 2.8e-30 105.0 2.3 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KKK12505.1 - 2.3e-21 75.8 0.0 4.1e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK12505.1 - 1.2e-08 34.3 0.1 2.9e-08 33.1 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 KKK12505.1 - 4e-05 22.5 0.0 0.17 10.6 0.0 2.2 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 KKK12505.1 - 0.0026 17.2 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KKK12505.1 - 0.017 15.4 1.7 0.044 14.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Miro PF08477.8 KKK12505.1 - 0.018 15.4 0.0 0.085 13.3 0.0 2.1 2 1 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 KKK12505.1 - 0.026 14.3 0.0 0.77 9.5 0.0 2.3 1 1 1 2 2 2 0 Dynamin family DnaJ PF00226.26 KKK12506.1 - 5.3e-22 77.3 0.7 1e-21 76.4 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 KKK12507.1 - 1.3e-26 93.0 0.0 2e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12507.1 - 6.6e-09 35.5 12.6 1e-08 34.9 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adenylsucc_synt PF00709.16 KKK12508.1 - 1.6e-141 471.7 0.0 1.1e-125 419.5 0.0 2.0 1 1 1 2 2 2 2 Adenylosuccinate synthetase DEAD PF00270.24 KKK12509.1 - 1.3e-43 148.4 0.0 3.7e-43 146.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK12509.1 - 7.8e-22 76.9 0.5 3e-20 71.8 0.1 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK12509.1 - 0.0031 17.3 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KKK12509.1 - 0.032 13.5 0.1 0.13 11.5 0.1 1.9 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_22 PF13401.1 KKK12509.1 - 0.055 13.6 0.0 0.45 10.6 0.0 2.5 3 1 0 3 3 3 0 AAA domain Bac_rhamnosid PF05592.6 KKK12514.1 - 0.073 11.2 0.1 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase MFS_1 PF07690.11 KKK12515.1 - 2.2e-50 171.3 39.3 3.1e-50 170.8 27.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK12515.1 - 8.8e-12 44.3 19.9 8.8e-12 44.3 13.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KKK12515.1 - 0.00091 17.4 1.7 0.00091 17.4 1.2 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector DUF2583 PF10762.4 KKK12515.1 - 4.3 7.5 7.6 0.42 10.7 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) MFS_1 PF07690.11 KKK12516.1 - 4.7e-30 104.4 34.0 4.7e-30 104.4 23.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK12516.1 - 1.1e-11 44.0 7.0 1.1e-11 44.0 4.8 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Beta-lactamase PF00144.19 KKK12517.1 - 6.1e-39 133.9 0.0 1.7e-38 132.4 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase FAD_binding_4 PF01565.18 KKK12517.1 - 7.6e-31 106.4 0.1 1.3e-30 105.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK12517.1 - 0.00016 21.5 0.3 0.0028 17.5 0.2 2.4 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.11 KKK12518.1 - 2.5e-30 105.4 28.7 2.5e-30 105.4 19.9 1.8 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF1993 PF09351.5 KKK12520.1 - 9.8e-51 171.8 0.0 1.1e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Peptidase_M43 PF05572.8 KKK12521.1 - 6.6e-12 45.2 0.1 1.5e-11 44.1 0.1 1.6 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 KKK12521.1 - 0.0035 17.4 0.0 0.0051 16.8 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KKK12521.1 - 0.024 14.3 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.1 KKK12521.1 - 0.1 12.1 0.1 0.43 10.0 0.1 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KKK12521.1 - 0.12 12.9 0.8 0.56 10.7 0.2 2.3 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KKK12521.1 - 0.13 12.1 0.2 0.45 10.4 0.1 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12 Abhydrolase_6 PF12697.2 KKK12522.1 - 6.1e-23 81.8 0.3 8e-23 81.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK12522.1 - 1.2e-10 41.2 0.1 1.5e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK12522.1 - 5.9e-07 29.3 0.1 1.1e-06 28.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KKK12522.1 - 0.00069 19.9 0.0 0.00085 19.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 KKK12522.1 - 0.0099 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.7 KKK12522.1 - 0.028 13.9 0.1 0.1 12.0 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase IFT57 PF10498.4 KKK12522.1 - 0.067 11.9 0.1 0.088 11.5 0.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NAD_binding_1 PF00175.16 KKK12523.1 - 4.5e-23 81.8 0.0 6.5e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KKK12523.1 - 6.4e-13 48.6 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KKK12523.1 - 5.2e-06 26.4 0.0 0.004 17.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain MFS_1 PF07690.11 KKK12524.1 - 1.3e-10 40.5 0.2 1.8e-10 40.0 0.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KKK12524.1 - 0.0045 15.4 0.8 0.0062 14.9 0.5 1.3 1 1 0 1 1 1 1 MFS/sugar transport protein ATG22 PF11700.3 KKK12524.1 - 0.03 12.8 1.6 1.4 7.3 0.3 2.1 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like LacY_symp PF01306.14 KKK12524.1 - 0.04 12.4 0.4 0.21 10.0 0.4 1.9 2 0 0 2 2 2 0 LacY proton/sugar symporter DUF2663 PF10864.3 KKK12524.1 - 0.041 14.1 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Peroxidase_2 PF01328.12 KKK12526.1 - 7.1e-16 57.7 1.7 4.1e-15 55.2 1.2 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 Glyco_hydro_3 PF00933.16 KKK12526.1 - 0.16 10.9 0.0 0.56 9.1 0.0 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 N terminal domain Ferric_reduct PF01794.14 KKK12527.1 - 1.1e-21 77.2 13.6 2.9e-21 75.8 9.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KKK12527.1 - 1e-15 57.9 0.0 1.6e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KKK12527.1 - 5.3e-10 39.1 0.0 0.001 18.9 0.0 2.7 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 KKK12527.1 - 0.00038 21.0 0.0 0.024 15.1 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Pyr_redox_3 PF13738.1 KKK12528.1 - 4.4e-23 82.4 0.0 6.6e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK12528.1 - 6.6e-17 60.9 0.4 2.6e-15 55.6 0.0 2.8 2 2 1 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK12528.1 - 4.6e-11 42.2 0.1 7.8e-10 38.1 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK12528.1 - 3.1e-08 33.5 3.5 1.9e-07 31.0 0.2 3.2 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK12528.1 - 5e-07 29.8 0.0 5.8e-06 26.3 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK12528.1 - 9.3e-06 24.7 0.6 0.0013 17.6 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 KKK12528.1 - 2.2e-05 23.5 0.1 0.0083 15.0 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK12528.1 - 0.00029 21.1 0.4 1 9.8 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK12528.1 - 0.00086 18.2 0.0 0.0017 17.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK12528.1 - 0.0014 17.7 0.1 0.0014 17.7 0.0 2.1 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.9 KKK12528.1 - 0.0099 14.3 0.3 0.037 12.5 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 KKK12528.1 - 1.9 8.2 6.6 5.5 6.7 0.2 3.8 3 2 0 3 3 3 0 FAD-NAD(P)-binding Cyt-b5 PF00173.23 KKK12529.1 - 3e-20 71.8 0.1 7.2e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KKK12529.1 - 5.4e-19 67.4 0.3 1.1e-18 66.4 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KKK12529.1 - 1.6e-18 67.2 1.9 1.9e-17 63.7 1.4 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KKK12529.1 - 3.3e-05 24.4 0.3 0.00011 22.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Tn916-Xis PF09035.5 KKK12529.1 - 0.027 14.5 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Excisionase from transposon Tn916 fn3_3 PF14686.1 KKK12530.1 - 2.9e-13 49.7 0.9 2.9e-13 49.7 0.6 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.1 KKK12530.1 - 4.5e-11 42.6 0.0 1.1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.1 KKK12530.1 - 0.00036 20.5 0.1 0.0015 18.5 0.1 2.1 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 KKK12530.1 - 0.08 12.7 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) Metallophos PF00149.23 KKK12531.1 - 7.7e-44 149.4 0.8 1e-43 149.1 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI31_Prot_N PF11566.3 KKK12532.1 - 1.7e-31 108.8 0.0 2.2e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KKK12532.1 - 1.2e-16 61.0 18.2 1.2e-16 61.0 12.6 3.0 3 1 0 3 3 3 1 PI31 proteasome regulator HAD_2 PF13419.1 KKK12533.1 - 2.2e-14 54.0 0.0 3.5e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK12533.1 - 3.6e-06 26.6 0.3 5.6e-05 22.7 0.1 2.6 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KKK12533.1 - 1.9e-05 25.1 0.0 0.00023 21.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT5C PF06941.7 KKK12533.1 - 0.0075 15.7 0.0 0.044 13.2 0.0 2.0 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) EBP PF05241.7 KKK12534.1 - 8e-65 217.4 8.2 9.2e-65 217.2 5.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein TPR_11 PF13414.1 KKK12536.1 - 6.3e-12 44.9 4.9 2.4e-11 43.1 1.3 2.4 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 KKK12536.1 - 3.4e-05 23.6 0.7 9.8e-05 22.2 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK12536.1 - 0.0003 20.2 6.5 0.072 12.7 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK12536.1 - 0.0019 18.3 1.4 0.0034 17.4 0.4 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KKK12536.1 - 0.012 15.7 0.2 0.36 11.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK12536.1 - 0.028 14.3 5.2 4.7 7.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK12536.1 - 0.053 13.3 0.2 5.8 6.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1250 PF06855.7 KKK12536.1 - 0.054 13.0 0.7 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) TPR_19 PF14559.1 KKK12536.1 - 0.059 13.7 0.2 0.059 13.7 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK12536.1 - 0.16 12.7 4.4 1.2 9.9 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK12536.1 - 2.1 8.9 5.6 11 6.6 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK12536.1 - 3 7.7 5.6 6.2 6.7 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Metal_resist PF13801.1 KKK12536.1 - 6.3 6.8 8.5 0.82 9.6 0.2 2.3 1 1 1 2 2 2 0 Heavy-metal resistance GMC_oxred_N PF00732.14 KKK12537.1 - 4.1e-32 111.5 0.0 1.2e-28 100.1 0.0 2.4 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK12537.1 - 3.3e-29 102.0 0.0 6.4e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KKK12537.1 - 6.9e-05 22.9 0.1 0.26 11.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK12537.1 - 0.00024 21.0 0.1 0.00065 19.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK12537.1 - 0.00047 20.0 0.0 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK12537.1 - 0.0011 17.9 0.0 0.0028 16.6 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK12537.1 - 0.0034 16.2 1.0 0.01 14.7 0.6 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KKK12537.1 - 0.012 14.5 1.2 0.18 10.6 0.6 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KKK12537.1 - 0.014 14.3 0.2 0.43 9.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 KKK12537.1 - 0.025 14.0 0.2 0.052 12.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HHH PF00633.18 KKK12537.1 - 0.038 13.6 1.4 4.8 7.0 0.0 3.1 4 0 0 4 4 4 0 Helix-hairpin-helix motif 3HCDH_N PF02737.13 KKK12537.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KKK12537.1 - 0.086 11.2 0.2 0.16 10.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein GidB PF02527.10 KKK12537.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G GDI PF00996.13 KKK12537.1 - 0.18 10.0 0.0 0.3 9.3 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor CFEM PF05730.6 KKK12538.1 - 1.6e-15 56.6 14.4 1.6e-15 56.6 9.9 1.8 2 0 0 2 2 2 1 CFEM domain Zn_clus PF00172.13 KKK12539.1 - 3.4e-09 36.4 9.6 6.5e-09 35.5 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK12539.1 - 3.4e-06 26.1 0.2 1.2e-05 24.3 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Vezatin PF12632.2 KKK12540.1 - 0.0048 15.9 0.1 0.0056 15.8 0.0 1.1 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Phosphodiest PF01663.17 KKK12541.1 - 8.9e-29 100.9 0.0 1.8e-28 99.9 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.17 KKK12541.1 - 5.7e-07 29.5 0.1 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 KKK12541.1 - 0.0058 15.9 0.1 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 HDOD domain DUF706 PF05153.10 KKK12541.1 - 0.038 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF706) PhyH PF05721.8 KKK12542.1 - 1.9e-29 103.2 0.1 1.9e-29 103.2 0.1 1.4 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KKK12542.1 - 9.6e-05 22.6 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Crystall PF00030.14 KKK12542.1 - 0.024 14.5 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Beta/Gamma crystallin Trehalase PF01204.13 KKK12544.1 - 9.3e-61 206.0 0.0 6.4e-42 143.8 0.1 3.0 1 1 1 2 2 2 2 Trehalase Trehalase_Ca-bi PF07492.6 KKK12544.1 - 2.3e-10 39.5 0.2 3.9e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF1399 PF07173.7 KKK12545.1 - 6.7e-22 78.2 1.1 4.7e-18 65.7 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Sugar_tr PF00083.19 KKK12546.1 - 6e-29 100.9 24.8 1.1e-28 100.1 17.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK12546.1 - 7.5e-14 51.2 31.8 7.5e-14 51.2 22.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Suc_Fer-like PF06999.7 KKK12547.1 - 2.7e-11 43.9 0.0 3.1e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-H2C2_2 PF13465.1 KKK12548.1 - 1.8e-18 65.8 20.8 6.4e-07 29.3 1.4 4.3 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KKK12548.1 - 1.4e-12 47.1 30.0 9e-05 22.5 3.6 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK12548.1 - 0.00026 21.0 28.1 0.02 15.1 3.0 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger Vps5 PF09325.5 KKK12550.1 - 1.2e-89 299.6 3.1 2e-89 298.9 2.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KKK12550.1 - 5.1e-25 87.4 0.0 1.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 PX domain His_Phos_2 PF00328.17 KKK12550.1 - 0.017 14.4 0.6 0.028 13.7 0.4 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Flavin_Reduct PF01613.13 KKK12552.1 - 8.1e-27 93.9 0.4 4.2e-20 72.1 0.4 2.4 2 0 0 2 2 2 2 Flavin reductase like domain Calreticulin PF00262.13 KKK12553.1 - 5.1e-161 535.3 15.4 5.1e-161 535.3 10.7 1.4 2 0 0 2 2 2 1 Calreticulin family IL13 PF03487.8 KKK12553.1 - 0.88 9.3 2.9 1.5 8.5 0.7 2.1 2 0 0 2 2 2 0 Interleukin-13 Aldolase_II PF00596.16 KKK12555.1 - 1.2e-41 142.3 0.0 1.5e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Complex1_LYR PF05347.10 KKK12556.1 - 6e-08 32.3 0.0 9.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK12556.1 - 2.3e-06 27.6 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KKK12556.1 - 7.6e-06 26.3 0.0 1e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RRM_1 PF00076.17 KKK12557.1 - 1.1e-11 44.1 0.1 7.7e-05 22.2 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK12557.1 - 1.2e-08 34.8 0.1 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK12557.1 - 7.8e-08 32.0 0.0 0.00013 21.7 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.1 KKK12557.1 - 0.082 12.3 0.1 6.9 6.2 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4651) Tubulin PF00091.20 KKK12558.1 - 1.5e-69 234.1 0.0 2.5e-69 233.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KKK12558.1 - 2.7e-50 169.6 0.1 4.6e-50 168.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KKK12558.1 - 1.6e-05 24.9 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KKK12558.1 - 0.0048 16.3 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Transp_cyt_pur PF02133.10 KKK12559.1 - 3.9e-14 52.0 36.5 7.9e-14 51.0 25.3 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ammonium_transp PF00909.16 KKK12560.1 - 1.7e-105 352.8 29.0 3.6e-103 345.1 20.1 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family Transgly_assoc PF04226.8 KKK12560.1 - 0.12 12.4 0.2 0.12 12.4 0.2 5.3 6 0 0 6 6 6 0 Transglycosylase associated protein Ceramidase PF05875.7 KKK12560.1 - 0.21 10.6 4.0 1.8 7.6 0.6 3.2 3 1 0 3 3 3 0 Ceramidase PH PF00169.24 KKK12578.1 - 1.2e-05 25.4 0.0 0.00044 20.4 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KKK12578.1 - 0.0028 17.8 0.0 0.0088 16.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Vps53_N PF04100.7 KKK12579.1 - 2.5e-109 365.5 1.6 2.5e-109 365.5 1.1 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal Sec6 PF06046.8 KKK12579.1 - 7e-10 37.6 1.4 1.1e-08 33.6 0.0 2.7 2 1 0 2 2 2 1 Exocyst complex component Sec6 DUF2450 PF10475.4 KKK12579.1 - 1.7e-07 30.4 7.5 3.4e-07 29.4 5.2 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 KKK12579.1 - 1.6e-06 26.9 5.3 3e-06 26.1 3.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein COG2 PF06148.6 KKK12579.1 - 7.8e-06 25.7 2.2 3.3e-05 23.7 1.5 2.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 RINT1_TIP1 PF04437.8 KKK12579.1 - 0.00011 20.9 1.8 0.00036 19.2 0.0 2.3 2 0 0 2 2 2 1 RINT-1 / TIP-1 family IncA PF04156.9 KKK12579.1 - 0.00053 19.6 6.3 0.0022 17.6 4.4 2.0 1 0 0 1 1 1 1 IncA protein DUF2451 PF10474.4 KKK12579.1 - 0.0016 18.2 0.5 0.0063 16.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Sigma70_ner PF04546.8 KKK12579.1 - 0.0044 16.6 6.7 0.028 14.0 3.4 2.2 2 0 0 2 2 2 1 Sigma-70, non-essential region Transposase_22 PF02994.9 KKK12579.1 - 0.0056 15.2 2.1 0.01 14.3 1.4 1.3 1 0 0 1 1 1 1 L1 transposable element AAA_13 PF13166.1 KKK12579.1 - 0.012 14.1 1.0 0.021 13.3 0.7 1.3 1 0 0 1 1 1 0 AAA domain DUF1515 PF07439.6 KKK12579.1 - 0.14 12.0 2.2 0.39 10.5 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF342 PF03961.8 KKK12579.1 - 0.16 10.3 1.2 0.27 9.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 KKK12579.1 - 0.42 8.4 3.1 0.63 7.8 2.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 KKK12579.1 - 0.5 10.0 7.9 0.088 12.5 2.4 2.1 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KKK12579.1 - 1.1 8.3 9.3 0.085 12.0 1.6 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 KKK12579.1 - 1.7 8.5 6.8 5.4 6.9 0.5 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TAP_C PF03943.8 KKK12580.1 - 5.9e-11 41.6 1.4 6.7e-11 41.4 0.2 1.7 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 KKK12580.1 - 8.8e-09 34.7 0.0 9.2e-05 21.9 0.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 KKK12580.1 - 6.7e-07 29.7 0.0 2e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 KKK12580.1 - 6.6e-05 22.5 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KKK12580.1 - 0.00036 20.1 0.0 3.3 8.0 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 KKK12580.1 - 0.0034 17.3 0.1 0.51 10.5 0.0 3.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_9 PF14580.1 KKK12580.1 - 0.0065 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 KKK12580.1 - 0.0065 16.4 0.3 3.3 8.3 0.1 3.2 2 0 0 2 2 2 1 Leucine rich repeat Coatamer_beta_C PF07718.7 KKK12580.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Coatomer beta C-terminal region COPIIcoated_ERV PF07970.7 KKK12581.1 - 8.3e-71 238.1 0.0 7.2e-47 159.8 0.0 2.6 2 1 1 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KKK12581.1 - 6.3e-34 115.8 0.0 1.4e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DSPc PF00782.15 KKK12582.1 - 9.6e-08 31.6 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KKK12582.1 - 0.022 13.6 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Aminotran_3 PF00202.16 KKK12583.1 - 2.8e-87 292.7 0.0 3.3e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SNF2_N PF00176.18 KKK12585.1 - 4.9e-68 229.1 0.5 1.2e-67 227.7 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK12585.1 - 2.3e-16 59.3 0.0 2.1e-15 56.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KKK12585.1 - 0.02 15.0 0.1 8 6.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain Kinesin PF00225.18 KKK12586.1 - 3.2e-98 328.5 0.0 7.6e-98 327.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Pkinase PF00069.20 KKK12587.1 - 3.4e-69 232.8 0.0 3.4e-68 229.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12587.1 - 7.6e-35 120.2 0.0 4.5e-29 101.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 KKK12587.1 - 7.1e-14 51.6 0.0 1.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KKK12587.1 - 4.3e-09 35.7 0.3 0.00081 18.4 0.1 3.0 2 1 1 3 3 3 2 Kinase-like APH PF01636.18 KKK12587.1 - 0.0002 21.1 0.1 0.0011 18.6 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KKK12587.1 - 0.0041 15.9 0.0 0.006 15.4 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KKK12587.1 - 0.0067 15.8 0.1 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KKK12587.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 KKK12588.1 - 7.2e-77 258.8 0.0 8.4e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IGR PF09597.5 KKK12589.1 - 2.3e-24 85.0 0.1 4.1e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 IGR protein motif Chorion_2 PF03964.10 KKK12589.1 - 0.01 16.3 1.2 0.017 15.6 0.9 1.4 1 0 0 1 1 1 0 Chorion family 2 Pkinase PF00069.20 KKK12590.1 - 4.8e-64 216.0 0.0 5.5e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12590.1 - 2.1e-33 115.5 0.0 3.1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK12590.1 - 0.034 13.1 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PI3_PI4_kinase PF00454.22 KKK12591.1 - 7.9e-36 123.7 0.1 5.2e-35 121.0 0.0 2.4 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KKK12591.1 - 3.4e-24 85.0 0.2 7.3e-24 83.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF607 PF04678.8 KKK12593.1 - 9.3e-45 152.7 0.0 9.3e-45 152.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF607 Sugar_tr PF00083.19 KKK12595.1 - 1.8e-92 310.2 19.9 2.2e-92 309.9 13.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK12595.1 - 1.5e-26 92.9 26.1 1.1e-18 67.0 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KKK12595.1 - 0.0042 16.8 7.0 1.5 8.6 0.0 4.4 4 0 0 4 4 4 2 MFS_1 like family DUF1228 PF06779.9 KKK12595.1 - 0.56 10.2 5.5 4 7.5 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Alpha-L-AF_C PF06964.7 KKK12596.1 - 1.2e-31 109.8 2.0 2.4e-31 108.8 1.4 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Cutinase PF01083.17 KKK12597.1 - 5.3e-50 169.6 0.1 6.2e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 KKK12597.1 - 0.00013 21.8 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 KKK12597.1 - 0.00037 20.0 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Creb_binding PF09030.5 KKK12597.1 - 0.012 15.8 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Creb binding Abhydrolase_2 PF02230.11 KKK12597.1 - 0.044 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase zf-C2H2_4 PF13894.1 KKK12599.1 - 0.0019 18.3 19.8 0.11 12.8 0.0 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KKK12599.1 - 0.0061 16.4 0.6 0.12 12.3 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK12599.1 - 0.049 13.9 24.3 0.91 9.9 0.1 5.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-met PF12874.2 KKK12599.1 - 0.24 11.6 1.8 10 6.4 0.4 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK12599.1 - 6.2 7.0 6.3 32 4.8 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ATP_transf PF09830.4 KKK12600.1 - 5.3e-23 80.5 0.0 1e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase GalP_UDP_transf PF01087.17 KKK12600.1 - 0.033 14.2 0.0 0.08 12.9 0.0 1.6 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain GST_N_3 PF13417.1 KKK12601.1 - 4.8e-11 42.7 0.0 7.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KKK12601.1 - 4.7e-08 33.0 0.0 8.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK12601.1 - 7.5e-08 32.2 0.0 1.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK12601.1 - 0.00021 21.2 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK12601.1 - 0.0071 16.2 0.2 0.015 15.2 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KKK12601.1 - 0.03 14.6 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain GST_C_3 PF14497.1 KKK12601.1 - 0.033 14.6 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain APH PF01636.18 KKK12602.1 - 1.8e-14 54.0 0.0 1.3e-13 51.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3680 PF12441.3 KKK12602.1 - 0.099 12.5 0.6 2.2 8.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3680) AA_permease_2 PF13520.1 KKK12604.1 - 3.4e-37 127.9 47.3 4.2e-37 127.6 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK12604.1 - 1.7e-16 59.6 38.9 2.2e-16 59.3 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_3 PF13302.1 KKK12605.1 - 1.6e-13 51.0 0.0 2.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK12605.1 - 2.9e-12 46.4 0.1 4.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KKK12605.1 - 1.2e-09 38.3 0.1 2.5e-09 37.2 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK12605.1 - 6.4e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KKK12605.1 - 0.00012 21.9 0.3 0.00063 19.6 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK12605.1 - 0.1 12.3 0.1 0.33 10.7 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein GMC_oxred_N PF00732.14 KKK12606.1 - 3.7e-79 265.9 0.0 5.3e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK12606.1 - 1.6e-36 125.7 0.0 3.5e-36 124.6 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK12606.1 - 5.9e-07 28.6 0.2 0.013 14.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK12606.1 - 4.9e-06 25.6 0.5 0.0061 15.5 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KKK12606.1 - 0.00064 18.7 0.1 0.001 18.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 KKK12606.1 - 0.0025 16.7 0.1 0.033 13.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KKK12606.1 - 0.009 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK12606.1 - 0.013 14.6 0.1 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 KKK12606.1 - 0.031 14.2 0.4 0.08 12.9 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KKK12606.1 - 0.054 12.5 3.7 0.04 12.9 0.7 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KKK12606.1 - 0.081 11.3 0.3 0.17 10.2 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 KKK12606.1 - 0.13 10.8 0.1 0.2 10.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GST_N_3 PF13417.1 KKK12607.1 - 5.8e-18 64.8 0.1 1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK12607.1 - 9.3e-15 54.3 0.0 1.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KKK12607.1 - 1.1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KKK12607.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Peptidase_S15 PF02129.13 KKK12608.1 - 1.3e-38 133.0 0.3 2.7e-36 125.3 0.1 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KKK12608.1 - 6.1e-13 49.1 0.0 1e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KKK12608.1 - 3.4e-05 23.8 0.1 6.5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK12608.1 - 0.0012 18.6 0.4 0.019 14.8 0.3 2.3 2 0 0 2 2 2 1 Putative lysophospholipase IN_DBD_C PF00552.16 KKK12608.1 - 0.011 15.1 0.2 0.033 13.6 0.1 1.8 1 0 0 1 1 1 0 Integrase DNA binding domain Agglutinin PF07468.6 KKK12609.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 Agglutinin Abhydrolase_6 PF12697.2 KKK12610.1 - 1.4e-19 70.8 0.0 3.2e-18 66.4 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family DSBA PF01323.15 KKK12610.1 - 7.5e-11 41.9 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Abhydrolase_5 PF12695.2 KKK12610.1 - 1.1e-07 31.7 0.0 2.3e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK12610.1 - 0.031 13.8 0.1 0.07 12.6 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 KKK12610.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF1090 PF06476.7 KKK12613.1 - 0.042 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) WD40 PF00400.27 KKK12614.1 - 8e-09 35.0 0.4 6.8e-07 28.9 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat 2-Hacid_dh_C PF02826.14 KKK12615.1 - 2.4e-39 134.3 0.1 3.1e-26 91.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KKK12615.1 - 0.0037 16.9 0.1 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK12615.1 - 0.097 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KKK12615.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase EthD PF07110.6 KKK12616.1 - 0.008 17.0 0.1 0.042 14.7 0.1 1.9 1 1 0 1 1 1 1 EthD domain PBP PF01161.15 KKK12617.1 - 1.2e-16 60.8 0.1 1.7e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FSH1 PF03959.8 KKK12618.1 - 5.1e-28 97.9 0.0 6.6e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KKK12618.1 - 1e-08 35.3 1.0 2.8e-07 30.6 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK12618.1 - 4.6e-06 26.4 0.0 8.8e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KKK12618.1 - 0.0084 15.5 0.1 0.29 10.5 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KKK12618.1 - 0.061 12.8 0.2 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Prok_Ub PF14454.1 KKK12618.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Ubiquitin ketoacyl-synt PF00109.21 KKK12619.1 - 9.1e-50 169.4 0.3 6.7e-49 166.6 0.0 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KKK12619.1 - 3.8e-36 123.5 0.6 7.4e-36 122.6 0.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KKK12619.1 - 3.1e-30 105.5 0.2 1.9e-27 96.4 0.0 2.4 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.1 KKK12619.1 - 1.7e-08 33.9 0.0 3.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 KKK12619.1 - 1.5e-05 24.1 0.5 3.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KKK12619.1 - 0.64 9.7 5.5 0.27 10.9 0.3 2.6 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Myosin_head PF00063.16 KKK12620.1 - 1.1e-233 777.3 2.5 1.6e-233 776.7 1.7 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KKK12620.1 - 2e-50 170.8 0.0 4.1e-50 169.8 0.0 1.6 1 0 0 1 1 1 1 Myosin tail OPA3 PF07047.7 KKK12620.1 - 1.5e-32 112.1 1.6 4.1e-32 110.7 1.1 1.7 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SH3_1 PF00018.23 KKK12620.1 - 4.7e-12 45.1 0.0 8.3e-12 44.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK12620.1 - 2.2e-08 33.4 0.0 5.3e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KKK12620.1 - 2.7e-07 30.0 0.0 5.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 KKK12620.1 - 0.002 17.5 6.8 0.46 10.2 0.4 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KKK12620.1 - 0.0043 17.2 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK12620.1 - 0.029 15.1 0.0 0.09 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 KKK12620.1 - 0.035 13.4 0.7 2.1 7.6 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.1 KKK12620.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK12620.1 - 0.093 12.3 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Med11 PF10280.4 KKK12620.1 - 0.25 11.3 2.5 0.23 11.5 0.3 2.0 2 0 0 2 2 2 0 Mediator complex protein Pkinase PF00069.20 KKK12621.1 - 2e-70 236.8 0.1 1.5e-69 234.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12621.1 - 7.5e-45 153.0 0.0 1.1e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK12621.1 - 2.6e-08 33.2 0.0 5.2e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like POLO_box PF00659.13 KKK12621.1 - 2.7e-08 33.6 0.2 0.0018 18.2 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 KKK12621.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chitin_synth_2 PF03142.10 KKK12622.1 - 1.4e-286 950.9 0.0 2.1e-286 950.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KKK12622.1 - 6.6e-15 55.3 3.2 3e-14 53.1 2.2 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK12622.1 - 7.7e-13 48.7 0.0 1.9e-10 40.9 0.0 2.7 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KKK12622.1 - 6.7e-10 38.6 0.2 5.5e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 KKK12622.1 - 2.3e-05 24.1 0.0 0.003 17.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KKK12622.1 - 0.00012 21.4 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Sel1 PF08238.7 KKK12623.1 - 6.5e-36 121.9 30.5 2.7e-06 27.8 0.3 7.7 7 0 0 7 7 7 7 Sel1 repeat DUF3112 PF11309.3 KKK12624.1 - 1.3e-40 138.8 15.9 1.2e-37 129.1 4.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) DUF4407 PF14362.1 KKK12624.1 - 0.0051 15.8 1.7 0.0054 15.7 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Methyltransf_23 PF13489.1 KKK12625.1 - 4.9e-16 58.8 0.1 2.1e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK12625.1 - 8.5e-15 55.0 0.2 2.2e-14 53.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 KKK12625.1 - 8.4e-13 48.3 1.2 1.9e-12 47.2 0.9 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.1 KKK12625.1 - 1.4e-09 37.5 0.0 1.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_11 PF08241.7 KKK12625.1 - 5.2e-09 36.4 0.1 7.3e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK12625.1 - 3.6e-08 33.1 0.0 1.3e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK12625.1 - 3.4e-06 27.6 0.0 1.2e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK12625.1 - 8.8e-06 26.0 0.0 2.2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK12625.1 - 0.00044 20.2 0.0 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK12625.1 - 0.00094 18.3 0.0 0.0039 16.3 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KKK12625.1 - 0.0014 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 KKK12625.1 - 0.039 14.7 0.0 3 8.7 0.0 3.6 4 1 0 4 4 3 0 Methyltransferase domain SURF4 PF02077.10 KKK12627.1 - 3.3e-94 315.2 8.5 3.7e-94 315.0 5.9 1.0 1 0 0 1 1 1 1 SURF4 family DJ-1_PfpI PF01965.19 KKK12647.1 - 2.9e-19 69.0 0.1 4.3e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KKK12647.1 - 1.1e-14 53.6 0.0 2.5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family BNR PF02012.15 KKK12648.1 - 1.4e-11 42.3 42.2 0.093 12.6 0.1 9.9 8 0 0 8 8 8 8 BNR/Asp-box repeat CBM_1 PF00734.13 KKK12648.1 - 1.9e-11 43.4 14.5 1.9e-11 43.4 10.1 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain TEX19 PF15553.1 KKK12648.1 - 0.049 13.5 0.1 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF2452 PF10504.4 KKK12648.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) p450 PF00067.17 KKK12649.1 - 3.5e-54 184.0 0.2 4.8e-54 183.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_45 PF02015.11 KKK12650.1 - 2.4e-10 40.8 8.8 4.2e-10 40.0 6.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 45 DPBB_1 PF03330.13 KKK12650.1 - 9.6e-09 35.1 0.2 1.3e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel CRAL_TRIO PF00650.15 KKK12651.1 - 7.9e-38 129.4 0.0 1.3e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KKK12651.1 - 3e-07 30.4 0.0 5.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK12651.1 - 0.0036 17.3 0.1 0.02 15.0 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Trp_DMAT PF11991.3 KKK12652.1 - 3.1e-99 332.6 0.0 3.8e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase TyeA PF09059.5 KKK12652.1 - 0.064 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TyeA UXS1_N PF11803.3 KKK12652.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal ABC_tran PF00005.22 KKK12653.1 - 1.6e-52 177.4 0.0 3.9e-30 104.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK12653.1 - 3.2e-29 102.2 17.5 4.3e-17 62.4 5.0 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KKK12653.1 - 1.4e-08 34.2 0.0 0.0013 18.0 0.0 3.8 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KKK12653.1 - 7.9e-07 29.2 0.3 0.039 13.9 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KKK12653.1 - 1.6e-06 28.2 0.3 0.26 11.2 0.0 4.5 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KKK12653.1 - 5.7e-06 25.8 0.1 0.093 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KKK12653.1 - 7.4e-06 25.2 0.1 0.02 14.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK12653.1 - 1e-05 25.6 0.7 0.13 12.3 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KKK12653.1 - 2.2e-05 24.8 0.1 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KKK12653.1 - 3.5e-05 23.3 0.1 0.077 12.4 0.0 3.1 2 1 1 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 KKK12653.1 - 0.00044 19.4 0.3 0.23 10.5 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 KKK12653.1 - 0.00055 20.7 0.0 0.13 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KKK12653.1 - 0.0006 19.7 0.2 0.28 11.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KKK12653.1 - 0.00084 18.8 0.3 1.4 8.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KKK12653.1 - 0.0014 18.0 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family UPF0079 PF02367.12 KKK12653.1 - 0.0025 17.4 0.1 0.054 13.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KKK12653.1 - 0.0071 16.0 0.8 0.88 9.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain ATP-synt_ab PF00006.20 KKK12653.1 - 0.0079 15.7 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 KKK12653.1 - 0.0086 15.5 0.1 0.22 10.8 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SE PF00437.15 KKK12653.1 - 0.01 14.7 0.0 2.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 KKK12653.1 - 0.014 15.9 0.2 6.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 KKK12653.1 - 0.019 14.5 0.0 6 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KKK12653.1 - 0.021 15.1 0.0 6.6 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 KKK12653.1 - 0.021 14.2 0.9 0.4 10.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KKK12653.1 - 0.022 14.9 0.2 8.6 6.5 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KKK12653.1 - 0.028 13.3 0.2 0.35 9.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KKK12653.1 - 0.032 14.3 0.0 9.1 6.5 0.0 2.9 3 0 0 3 3 3 0 RNA helicase KaiC PF06745.8 KKK12653.1 - 0.034 13.2 0.0 1.9 7.5 0.0 2.5 2 0 0 2 2 2 0 KaiC MobB PF03205.9 KKK12653.1 - 0.047 13.4 0.2 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KKK12653.1 - 0.062 13.1 5.3 0.093 12.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 APS_kinase PF01583.15 KKK12653.1 - 0.1 12.2 0.5 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase TrwB_AAD_bind PF10412.4 KKK12653.1 - 0.2 10.2 0.8 5.2 5.5 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MFS_1 PF07690.11 KKK12654.1 - 6.4e-14 51.4 12.9 1.1e-13 50.6 8.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 KKK12655.1 - 1.4e-62 211.7 0.0 1.8e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PALP PF00291.20 KKK12656.1 - 3.5e-20 72.4 0.0 3.6e-12 46.1 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 KKK12656.1 - 0.054 12.4 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 LytB protein zf-RNPHF PF08080.7 KKK12656.1 - 0.23 11.0 1.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 RNPHF zinc finger Git3 PF11710.3 KKK12657.1 - 2.4e-24 86.0 8.4 2.4e-24 86.0 5.8 1.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KKK12657.1 - 6.6e-09 35.4 1.3 1.3e-08 34.4 0.1 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KKK12657.1 - 1.3e-05 24.4 6.0 1.4e-05 24.4 3.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPDPase_memb PF10110.4 KKK12657.1 - 0.0022 17.4 0.3 0.0022 17.4 0.2 2.0 2 0 0 2 2 2 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Dicty_CAR PF05462.6 KKK12657.1 - 0.0029 16.5 3.5 0.004 16.1 2.4 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Con-6 PF10346.4 KKK12658.1 - 4.4e-37 125.2 10.8 8.4e-16 57.0 0.1 3.5 3 0 0 3 3 3 3 Conidiation protein 6 Replicase PF03090.12 KKK12658.1 - 0.0017 18.1 0.2 0.26 11.1 0.0 2.2 2 0 0 2 2 2 2 Replicase family SpoIIIAH PF12685.2 KKK12658.1 - 0.084 12.3 1.5 4.1 6.8 0.1 2.7 3 0 0 3 3 3 0 SpoIIIAH-like protein Sugar_tr PF00083.19 KKK12659.1 - 1.9e-124 415.7 27.8 2.1e-124 415.5 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK12659.1 - 7.5e-24 84.0 69.9 4.9e-22 78.1 25.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1399 PF07173.7 KKK12661.1 - 8.2e-20 71.4 0.2 9.7e-15 55.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Lar_restr_allev PF14354.1 KKK12661.1 - 0.026 14.8 1.0 0.088 13.1 0.1 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Glyco_hydro_16 PF00722.16 KKK12662.1 - 8.1e-39 132.8 3.6 1.2e-38 132.2 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.1 KKK12662.1 - 0.06 13.5 3.5 0.087 13.0 2.3 1.5 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily HsbA PF12296.3 KKK12663.1 - 7.4e-24 83.9 12.3 7.4e-24 83.9 8.5 4.1 2 1 1 3 3 3 1 Hydrophobic surface binding protein A Syntaxin PF00804.20 KKK12663.1 - 0.57 10.3 4.0 1.4 9.1 0.3 2.9 1 1 1 3 3 3 0 Syntaxin CLASP_N PF12348.3 KKK12663.1 - 1.2 8.4 9.5 0.038 13.3 1.9 1.8 1 1 0 1 1 1 0 CLASP N terminal Aha1_N PF09229.6 KKK12664.1 - 8.2e-40 135.8 0.4 1.4e-39 135.0 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KKK12664.1 - 1e-17 64.3 0.9 1.6e-17 63.7 0.2 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 KKK12664.1 - 0.017 15.2 0.8 0.028 14.5 0.5 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein DUF2454 PF10521.4 KKK12664.1 - 0.092 11.7 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) FBPase PF00316.15 KKK12666.1 - 3.2e-106 354.8 0.1 5.5e-65 219.3 0.0 2.0 1 1 1 2 2 2 2 Fructose-1-6-bisphosphatase rRNA_processing PF08524.6 KKK12687.1 - 0.046 13.5 0.0 0.046 13.5 0.0 2.7 3 0 0 3 3 3 0 rRNA processing DUF1151 PF06625.6 KKK12687.1 - 1.3 8.7 9.8 6.8 6.4 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Eaf7 PF07904.8 KKK12688.1 - 2.7e-30 104.1 0.0 2.7e-30 104.1 0.0 1.9 2 0 0 2 2 1 1 Chromatin modification-related protein EAF7 Nop14 PF04147.7 KKK12688.1 - 0.00084 17.4 14.5 0.00098 17.1 10.1 1.1 1 0 0 1 1 1 1 Nop14-like family Prothymosin PF03247.9 KKK12688.1 - 0.037 14.1 25.4 0.088 12.9 17.6 1.6 1 0 0 1 1 1 0 Prothymosin/parathymosin family Daxx PF03344.10 KKK12688.1 - 0.047 12.1 19.3 0.081 11.3 13.4 1.3 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 KKK12688.1 - 0.064 13.1 16.7 0.049 13.5 8.7 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAXIP1_C PF15364.1 KKK12688.1 - 0.32 10.9 10.3 0.84 9.5 7.1 1.6 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein NOA36 PF06524.7 KKK12688.1 - 0.68 9.1 14.4 0.97 8.6 10.0 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.6 KKK12688.1 - 0.74 9.3 12.6 1 8.8 8.7 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 KKK12688.1 - 0.75 7.7 18.9 0.96 7.4 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.3 KKK12688.1 - 0.86 9.0 7.4 14 5.1 5.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Cwf_Cwc_15 PF04889.7 KKK12688.1 - 1.5 8.4 14.7 2.3 7.8 10.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 KKK12688.1 - 2.7 7.1 19.4 4.3 6.5 13.5 1.2 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.9 KKK12688.1 - 4.4 6.7 9.8 7.8 5.9 6.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop53 PF07767.6 KKK12688.1 - 4.9 6.0 15.4 5.7 5.8 8.4 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Ribosomal_L18p PF00861.17 KKK12689.1 - 7.9e-43 145.4 0.2 7.9e-43 145.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KKK12689.1 - 1.1e-32 112.4 7.8 1.1e-32 112.4 5.4 2.0 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region HAD_2 PF13419.1 KKK12689.1 - 1.8e-15 57.5 0.5 1.4e-14 54.6 0.0 2.5 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Metal_resist PF13801.1 KKK12689.1 - 0.073 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Heavy-metal resistance FTA4 PF13093.1 KKK12690.1 - 6e-72 241.5 13.3 7e-72 241.3 9.2 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3510 PF12022.3 KKK12690.1 - 0.069 13.2 0.8 0.22 11.6 0.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) Mnd1 PF03962.10 KKK12690.1 - 0.089 12.4 7.9 0.4 10.3 1.4 2.1 1 1 1 2 2 2 0 Mnd1 family Hrs_helical PF12210.3 KKK12690.1 - 0.98 9.7 10.8 1.6 9.0 1.9 3.5 2 1 2 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate FUSC PF04632.7 KKK12690.1 - 5.4 5.3 5.7 6.5 5.0 3.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.7 KKK12691.1 - 0.043 13.9 1.6 0.1 12.7 1.1 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.7 KKK12691.1 - 0.059 13.7 3.6 0.083 13.2 0.2 2.7 3 0 0 3 3 3 0 SlyX GlutR_dimer PF00745.15 KKK12691.1 - 0.12 12.2 1.7 0.2 11.6 0.4 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain MFS_1 PF07690.11 KKK12692.1 - 3.5e-28 98.3 19.5 4.4e-28 98.0 13.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF718 PF05336.8 KKK12692.1 - 6.5e-13 48.4 0.1 1.1e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Pox_A14 PF05767.7 KKK12692.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Thiolase_N PF00108.18 KKK12694.1 - 1.7e-73 246.8 0.1 2.7e-73 246.2 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK12694.1 - 4.9e-40 135.7 0.4 4.9e-40 135.7 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KKK12694.1 - 0.0031 17.1 0.1 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KKK12694.1 - 0.009 15.5 1.5 0.027 13.9 0.7 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KKK12694.1 - 0.11 12.5 0.0 0.36 10.8 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal RhoGAP PF00620.22 KKK12695.1 - 6e-48 162.2 0.0 2e-47 160.6 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KKK12695.1 - 1.7e-13 50.4 20.5 8e-09 35.4 3.0 2.4 2 0 0 2 2 2 2 LIM domain TMF_TATA_bd PF12325.3 KKK12695.1 - 0.2 11.4 19.1 2.6 7.7 3.6 3.7 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DASH_Ask1 PF08655.5 KKK12696.1 - 7.3e-34 115.4 0.1 1.5e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 BSP PF04450.7 KKK12697.1 - 6.9e-71 237.9 0.0 9.6e-71 237.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 KKK12697.1 - 0.00082 19.4 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 KKK12697.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 SprT-like family CLASP_N PF12348.3 KKK12698.1 - 3.3e-154 510.7 2.0 1.7e-86 289.2 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 KKK12698.1 - 3.1e-10 39.2 0.2 0.0049 16.8 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 KKK12698.1 - 2.1e-07 31.0 1.7 0.24 11.7 0.1 4.7 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KKK12698.1 - 7.8e-05 23.0 0.3 0.69 10.4 0.0 4.3 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.2 KKK12698.1 - 8.7e-05 22.4 0.1 0.0047 16.7 0.0 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KKK12698.1 - 0.038 12.3 0.2 0.43 8.8 0.1 2.3 1 1 1 2 2 2 0 Adaptin N terminal region Ribonuclease_3 PF00636.21 KKK12700.1 - 1.6e-08 34.9 0.0 9.6e-08 32.4 0.0 2.2 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KKK12700.1 - 3.7e-08 33.3 0.0 0.001 19.0 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 KKK12700.1 - 1.1e-06 29.1 0.0 2.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF2333 PF10095.4 KKK12700.1 - 0.17 10.5 0.4 0.25 9.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) DUF4210 PF13915.1 KKK12701.1 - 4.6e-26 90.8 0.2 2e-25 88.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KKK12701.1 - 5e-23 80.7 0.4 1.4e-22 79.3 0.3 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis Sec5 PF15469.1 KKK12702.1 - 5.1e-34 117.5 0.0 1.5e-33 116.0 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 KKK12702.1 - 8.5e-06 25.5 0.1 4e-05 23.3 0.1 2.2 1 0 0 1 1 1 1 Vps51/Vps67 DUF4111 PF13427.1 KKK12702.1 - 0.076 12.8 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Iso_dh PF00180.15 KKK12703.1 - 7e-88 294.8 0.0 2.2e-57 194.5 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 KKK12703.1 - 0.011 15.5 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Spc97_Spc98 PF04130.8 KKK12704.1 - 1.5e-79 267.7 3.8 1.8e-79 267.5 2.6 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DOG1 PF14144.1 KKK12704.1 - 0.023 14.7 0.0 0.082 12.9 0.0 1.9 1 0 0 1 1 1 0 Seed dormancy control Mo-co_dimer PF03404.11 KKK12705.1 - 2.2e-56 189.0 0.0 4.2e-56 188.1 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KKK12705.1 - 1.2e-43 148.4 0.0 2.5e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KKK12705.1 - 5.7e-30 103.3 0.0 9.7e-30 102.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KKK12705.1 - 5.6e-27 94.4 0.0 1.2e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KKK12705.1 - 2.7e-13 49.4 0.0 5.6e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KKK12705.1 - 2.4e-05 24.2 1.6 0.03 14.2 0.0 3.0 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Thioredoxin_4 PF13462.1 KKK12705.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin SSP160 PF06933.6 KKK12705.1 - 3.1 5.6 9.8 4.5 5.1 6.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PfkB PF00294.19 KKK12706.1 - 2.1e-14 53.3 0.0 1.2e-13 50.9 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase CAP_N PF01213.14 KKK12707.1 - 1.3e-83 280.8 15.4 2.4e-82 276.7 10.7 2.0 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KKK12707.1 - 5.8e-46 155.7 2.1 9.1e-46 155.0 1.5 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KKK12707.1 - 0.0048 16.2 4.2 0.2 11.0 2.9 2.2 1 1 1 2 2 2 2 Tubulin binding cofactor C NIR_SIR PF01077.17 KKK12708.1 - 3e-30 104.6 0.0 6.9e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 KKK12708.1 - 6e-28 98.1 0.2 1.3e-27 97.0 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK12708.1 - 1.5e-17 63.7 2.1 3e-16 59.5 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KKK12708.1 - 2.8e-15 55.9 0.0 6.5e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 KKK12708.1 - 3e-14 52.7 4.3 1.3e-12 47.5 2.2 2.7 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 KKK12708.1 - 5.9e-12 45.0 0.0 1.9e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 KKK12708.1 - 8.7e-12 44.5 0.0 2e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 KKK12708.1 - 0.00089 19.3 0.0 0.0052 16.8 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK12708.1 - 0.0082 15.9 1.6 6.4 6.5 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KKK12708.1 - 0.015 13.7 0.0 1.2 7.5 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein adh_short PF00106.20 KKK12709.1 - 1.8e-07 31.1 0.0 1.7e-05 24.7 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK12709.1 - 0.026 14.2 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF1537 PF07005.6 KKK12710.1 - 3.5e-22 79.2 5.6 5.4e-22 78.5 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 WD40 PF00400.27 KKK12712.1 - 3.8e-35 118.5 7.5 5.6e-09 35.5 0.0 7.6 8 1 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 KKK12712.1 - 0.0013 18.5 0.1 0.43 10.2 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KKK12712.1 - 0.023 14.1 0.0 0.45 9.9 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.3 KKK12712.1 - 0.062 11.4 0.0 0.23 9.5 0.0 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 ABC2_membrane PF01061.19 KKK12713.1 - 1.4e-36 125.6 20.9 2.6e-36 124.7 14.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KKK12713.1 - 4e-25 88.6 0.0 7.4e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KKK12713.1 - 5.6e-09 36.3 0.0 1.9e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KKK12713.1 - 8.2e-05 21.7 27.3 8.2e-05 21.7 18.9 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 KKK12713.1 - 0.00073 18.9 0.0 0.053 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 KKK12713.1 - 0.0045 16.9 26.7 0.017 15.1 3.5 4.3 4 0 0 4 4 3 2 Human growth factor-like EGF AAA_29 PF13555.1 KKK12713.1 - 0.0053 16.2 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KKK12713.1 - 0.0074 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK12713.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KKK12713.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KKK12713.1 - 0.034 14.9 0.0 0.091 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KKK12713.1 - 0.034 14.0 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KKK12713.1 - 0.034 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_15 PF13175.1 KKK12713.1 - 0.038 13.0 0.0 3.1 6.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 KKK12713.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KKK12713.1 - 0.054 13.8 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK12713.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 KKK12713.1 - 0.086 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KKK12713.1 - 0.1 12.0 0.1 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 KKK12713.1 - 0.12 11.6 0.0 2.6 7.2 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 KKK12713.1 - 0.12 12.3 0.1 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.19 KKK12713.1 - 1 9.3 28.8 0.51 10.3 5.5 3.7 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) Cornichon PF03311.9 KKK12714.1 - 1.3e-47 161.0 11.5 3.1e-40 137.2 2.8 2.0 2 0 0 2 2 2 2 Cornichon protein Peptidase_M50 PF02163.17 KKK12714.1 - 0.029 13.3 1.7 0.04 12.8 1.2 1.1 1 0 0 1 1 1 0 Peptidase family M50 Fungal_trans PF04082.13 KKK12715.1 - 8.3e-33 113.3 0.1 5e-32 110.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12715.1 - 6.7e-10 38.7 13.1 1.2e-09 37.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSA-2c PF12238.3 KKK12715.1 - 0.88 9.1 3.8 0.47 10.0 0.1 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c DnaJ PF00226.26 KKK12716.1 - 8.2e-08 31.8 0.1 1.2e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KKK12716.1 - 1.5e-07 31.2 0.1 3.5e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 Pam16 DUF2648 PF10855.3 KKK12716.1 - 0.079 12.3 1.8 0.29 10.5 1.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2648) DUF3918 PF13056.1 KKK12716.1 - 8.2 5.8 12.4 0.16 11.3 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.15 KKK12717.1 - 5.6e-25 86.9 0.8 5.6e-25 86.9 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.9 KKK12717.1 - 0.041 13.5 1.6 0.087 12.4 1.1 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Cpn60_TCP1 PF00118.19 KKK12718.1 - 1.2e-147 492.4 2.2 1.4e-147 492.2 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chromo PF00385.19 KKK12719.1 - 7.3e-10 38.3 0.9 5.5e-09 35.5 0.1 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KKK12719.1 - 1.3e-08 34.5 0.0 7.2e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 Chromo shadow domain ORC6 PF05460.8 KKK12719.1 - 0.0007 18.7 2.5 0.0009 18.4 1.7 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Tox-REase-7 PF15649.1 KKK12719.1 - 0.075 13.1 0.4 0.075 13.1 0.3 2.0 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 Pap_E4 PF02711.9 KKK12719.1 - 0.5 11.2 4.1 0.98 10.2 2.8 1.4 1 0 0 1 1 1 0 E4 protein Rap1_C PF11626.3 KKK12720.1 - 2.3e-25 88.2 0.0 5.3e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KKK12720.1 - 1.5e-20 72.7 0.8 3.8e-20 71.4 0.6 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 KKK12720.1 - 1.2e-07 32.2 0.2 3.8e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Rap1, DNA-binding Atx10homo_assoc PF09759.4 KKK12721.1 - 2.2e-33 114.0 0.3 9.1e-33 112.0 0.0 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain TFIIA PF03153.8 KKK12721.1 - 1.4 8.7 7.5 2.3 7.9 5.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.1 KKK12722.1 - 1.1e-08 34.8 2.8 2.1e-08 33.8 2.0 1.5 1 0 0 1 1 1 1 Ring finger domain Pyridox_oxidase PF01243.15 KKK12722.1 - 1.1e-07 31.6 0.0 4.3e-05 23.4 0.0 3.1 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase zf-rbx1 PF12678.2 KKK12722.1 - 2.2e-05 24.4 0.3 4.9e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FAD_binding_6 PF00970.19 KKK12722.1 - 0.0003 20.8 0.0 0.0017 18.4 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain zf-Apc11 PF12861.2 KKK12722.1 - 0.0016 18.2 0.4 0.0031 17.3 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KKK12722.1 - 0.02 14.8 1.9 0.047 13.7 1.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NTP_transferase PF00483.18 KKK12723.1 - 1.6e-29 102.9 0.0 2.2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KKK12723.1 - 6.9e-08 31.6 9.5 6.1e-07 28.6 0.2 4.0 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KKK12723.1 - 1.1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 KKK12723.1 - 0.0028 17.2 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glycos_transf_2 PF00535.21 KKK12723.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2968 PF11180.3 KKK12723.1 - 0.055 12.8 0.1 0.088 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) CorA PF01544.13 KKK12725.1 - 1e-38 133.0 0.2 2e-38 132.0 0.1 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.2 KKK12726.1 - 1.3e-214 712.2 1.5 1.3e-214 712.2 1.1 1.7 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 Metallophos PF00149.23 KKK12730.1 - 2.3e-06 27.1 7.5 1.5e-05 24.5 4.7 2.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SAPS PF04499.10 KKK12730.1 - 0.013 14.2 0.7 0.017 13.7 0.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM176 PF14851.1 KKK12730.1 - 0.23 11.1 8.8 0.28 10.8 0.3 2.3 2 0 0 2 2 2 0 FAM176 family TFIIF_alpha PF05793.7 KKK12730.1 - 0.34 9.2 15.4 0.25 9.6 3.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleoplasmin PF03066.10 KKK12730.1 - 1.1 8.7 24.0 2.4 7.6 2.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin Kin17_mid PF10357.4 KKK12730.1 - 1.2 8.8 4.1 12 5.5 0.2 2.3 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein RR_TM4-6 PF06459.7 KKK12730.1 - 1.2 8.9 10.3 2.1 8.1 7.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Daxx PF03344.10 KKK12730.1 - 1.2 7.4 17.9 0.42 9.0 5.3 2.0 2 0 0 2 2 2 0 Daxx Family PBP1_TM PF14812.1 KKK12730.1 - 3.9 7.8 14.9 0.88 9.9 0.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 KKK12730.1 - 4.3 6.8 18.4 3.8 7.0 4.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region eIF-3c_N PF05470.7 KKK12730.1 - 6.5 4.7 7.1 9.5 4.1 4.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sporozoite_P67 PF05642.6 KKK12730.1 - 8.7 4.0 18.2 0.21 9.4 2.3 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen SH3_9 PF14604.1 KKK12731.1 - 6.6e-10 38.4 0.1 1.4e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK12731.1 - 7.7e-10 38.0 0.0 1.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KKK12731.1 - 1.8e-09 37.7 0.0 4.7e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 KKK12731.1 - 1.1e-08 34.8 0.1 1.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 KKK12731.1 - 6.8e-06 26.3 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 KKK12731.1 - 1.1e-05 24.7 0.1 2.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 KKK12731.1 - 0.068 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PAXIP1_C PF15364.1 KKK12731.1 - 0.26 11.2 5.0 0.09 12.6 1.0 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF2379 PF09543.5 KKK12732.1 - 0.018 15.0 0.7 0.13 12.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2379) PH PF00169.24 KKK12733.1 - 9.2e-26 90.0 0.4 3.6e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KKK12733.1 - 2.6e-12 46.9 1.0 5.6e-05 23.3 0.1 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KKK12733.1 - 1.8e-11 44.2 0.6 3.4e-06 27.1 0.1 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KKK12733.1 - 0.0014 18.6 0.1 0.1 12.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 KKK12733.1 - 0.018 15.0 0.0 0.7 9.9 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain EamA PF00892.15 KKK12734.1 - 6.9e-09 35.8 4.4 6.9e-09 35.8 3.1 3.1 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KKK12734.1 - 2.3e-07 30.0 6.5 2.3e-07 30.0 4.5 1.5 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 KKK12734.1 - 6.1e-05 23.2 6.8 6.1e-05 23.2 4.7 3.7 3 2 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 KKK12734.1 - 0.0002 20.3 9.2 0.0002 20.3 6.4 2.3 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 KKK12734.1 - 0.017 14.7 5.5 0.017 14.7 3.8 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family ATG16 PF08614.6 KKK12735.1 - 8.6e-45 152.9 18.8 5.2e-44 150.3 13.0 1.8 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KKK12735.1 - 0.0039 15.7 1.0 0.0045 15.5 0.7 1.1 1 0 0 1 1 1 1 AAA domain Prefoldin_2 PF01920.15 KKK12735.1 - 0.015 15.0 4.0 1.1 9.0 0.1 2.4 1 1 1 2 2 2 0 Prefoldin subunit Nup54 PF13874.1 KKK12735.1 - 0.018 14.7 7.6 0.25 11.0 1.1 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 APG6 PF04111.7 KKK12735.1 - 0.026 13.5 7.7 0.028 13.4 4.6 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 KKK12735.1 - 0.027 13.1 4.8 0.039 12.6 2.4 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4201 PF13870.1 KKK12735.1 - 0.036 13.4 12.7 0.031 13.7 6.7 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) IFT57 PF10498.4 KKK12735.1 - 0.053 12.2 3.2 0.056 12.1 2.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 IncA PF04156.9 KKK12735.1 - 0.09 12.3 8.4 0.16 11.5 5.7 1.5 1 1 0 1 1 1 0 IncA protein FliJ PF02050.11 KKK12735.1 - 0.095 12.7 6.6 0.26 11.3 0.3 2.8 1 1 1 2 2 2 0 Flagellar FliJ protein Tropomyosin PF00261.15 KKK12735.1 - 0.13 11.2 11.7 0.27 10.2 7.9 1.7 1 1 0 1 1 1 0 Tropomyosin DUF874 PF05917.6 KKK12735.1 - 0.24 10.2 3.6 0.38 9.5 2.4 1.3 1 1 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) CCDC-167 PF15188.1 KKK12735.1 - 0.47 10.4 10.7 1.5 8.8 4.3 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.14 KKK12735.1 - 0.53 8.0 3.5 0.66 7.7 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIVA PF05103.8 KKK12735.1 - 0.76 9.8 7.1 1.6 8.7 0.5 2.4 2 1 0 2 2 2 0 DivIVA protein Fez1 PF06818.10 KKK12735.1 - 1.1 9.2 12.2 0.18 11.8 2.9 2.2 1 1 1 2 2 2 0 Fez1 Nbl1_Borealin_N PF10444.4 KKK12735.1 - 1.2 8.5 5.4 5.2 6.5 0.8 2.7 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal GAS PF13851.1 KKK12735.1 - 1.5 7.9 9.0 1.3 8.1 4.1 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 KKK12735.1 - 2.4 8.5 6.2 20 5.6 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 KKK12735.1 - 6.3 6.5 10.0 5.9 6.6 2.1 2.9 1 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF4140 PF13600.1 KKK12735.1 - 7.1 7.1 12.2 5.6 7.4 0.7 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DOT1 PF08123.8 KKK12736.1 - 7e-59 198.5 0.0 5.4e-47 159.7 0.0 2.2 1 1 1 2 2 2 2 Histone methylation protein DOT1 FAM60A PF15396.1 KKK12736.1 - 2.3 7.9 5.3 4.5 6.9 3.7 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Nucleo_P87 PF07267.6 KKK12736.1 - 4.7 5.7 6.2 8.3 4.9 4.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spb1_C PF07780.7 KKK12737.1 - 2.1e-74 249.6 29.0 2.1e-74 249.6 20.1 2.9 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 KKK12737.1 - 4.4e-54 183.2 0.0 8.6e-54 182.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KKK12737.1 - 5.2e-54 182.0 7.5 5.2e-54 182.0 5.2 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) DUF2243 PF10002.4 KKK12738.1 - 0.2 11.4 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) Ran_BP1 PF00638.13 KKK12739.1 - 2.1e-50 169.8 2.0 2.1e-50 169.8 1.4 1.5 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 KKK12739.1 - 1.6e-05 24.5 0.3 0.00013 21.6 0.2 2.1 1 1 0 1 1 1 1 WH1 domain FHIPEP PF00771.15 KKK12739.1 - 0.12 10.6 1.4 0.16 10.2 1.0 1.2 1 0 0 1 1 1 0 FHIPEP family CDC27 PF09507.5 KKK12739.1 - 0.14 11.3 16.5 0.2 10.8 11.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4358 PF14270.1 KKK12739.1 - 0.23 11.3 5.5 3 7.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) Phasin PF05597.6 KKK12739.1 - 1.4 8.6 8.7 2.8 7.7 0.3 3.1 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TMEM247 PF15444.1 KKK12739.1 - 2.7 7.7 6.0 4 7.2 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Glyco_transf_15 PF01793.11 KKK12740.1 - 1.9e-132 441.2 2.5 2.3e-132 440.9 1.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4553 PF15090.1 KKK12740.1 - 0.21 10.5 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) Ras PF00071.17 KKK12741.1 - 8.1e-57 191.1 0.0 9.6e-57 190.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK12741.1 - 7.2e-20 71.6 0.0 1.1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK12741.1 - 3.7e-13 49.0 0.0 4.4e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KKK12741.1 - 3.7e-07 30.0 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK12741.1 - 1.3e-06 28.0 0.0 4e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KKK12741.1 - 1.7e-06 27.3 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KKK12741.1 - 0.00044 20.4 0.0 0.00085 19.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KKK12741.1 - 0.0013 17.9 0.1 0.0028 16.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KKK12741.1 - 0.0019 17.7 0.1 0.078 12.4 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KKK12741.1 - 0.0026 17.3 0.2 0.1 12.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KKK12741.1 - 0.0046 16.6 0.5 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase Septin PF00735.13 KKK12741.1 - 0.0048 15.9 0.1 0.033 13.2 0.0 2.1 2 0 0 2 2 2 1 Septin AAA_10 PF12846.2 KKK12741.1 - 0.0058 16.1 0.2 0.017 14.5 0.1 1.6 1 1 0 2 2 2 1 AAA-like domain AAA_24 PF13479.1 KKK12741.1 - 0.0066 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 KKK12741.1 - 0.0071 15.8 0.0 0.04 13.3 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KKK12741.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.1 KKK12741.1 - 0.012 15.6 0.0 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 KKK12741.1 - 0.015 14.5 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 KKK12741.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KKK12741.1 - 0.027 14.1 0.2 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KKK12741.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KKK12741.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 KKK12741.1 - 0.15 11.3 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B DNA_ligase_A_M PF01068.16 KKK12742.1 - 4.4e-45 153.5 0.0 1.2e-44 152.1 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KKK12742.1 - 1.7e-37 128.9 0.0 3.9e-37 127.7 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KKK12742.1 - 1.1e-16 60.9 0.0 4.6e-16 58.9 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KKK12742.1 - 1.3e-12 47.6 0.0 7.8e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain zf-C2H2 PF00096.21 KKK12742.1 - 4.7e-06 26.6 18.2 0.013 15.7 3.3 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK12742.1 - 6.9e-06 26.0 6.2 6.9e-06 26.0 4.3 2.6 2 0 0 2 2 2 1 Zinc-finger double domain Zn_clus PF00172.13 KKK12742.1 - 2e-05 24.3 9.6 2e-05 24.3 6.7 2.2 3 0 0 3 3 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_IV PF11411.3 KKK12742.1 - 0.00028 20.5 0.0 0.00065 19.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase IV zf-C2H2_4 PF13894.1 KKK12742.1 - 0.001 19.2 3.7 0.001 19.2 2.6 3.4 3 0 0 3 3 2 2 C2H2-type zinc finger zf-met PF12874.2 KKK12742.1 - 0.009 16.1 0.9 0.023 14.8 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK12742.1 - 0.087 12.9 7.2 1.9 8.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PTCB-BRCT PF12738.2 KKK12742.1 - 0.12 12.2 0.1 9.4 6.1 0.0 2.6 2 0 0 2 2 2 0 twin BRCT domain zf-C2H2_6 PF13912.1 KKK12742.1 - 3.2 7.7 7.3 20 5.2 1.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger GvpG PF05120.7 KKK12743.1 - 0.042 13.6 0.3 0.091 12.5 0.2 1.5 1 0 0 1 1 1 0 Gas vesicle protein G EF-hand_4 PF12763.2 KKK12744.1 - 1.5e-05 24.6 0.1 3.3e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Fungal_trans PF04082.13 KKK12745.1 - 2.7e-06 26.4 0.4 2.7e-06 26.4 0.3 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12745.1 - 0.017 14.9 9.6 0.048 13.5 6.7 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.11 KKK12746.1 - 9.7e-22 76.5 0.1 1.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family AAA_33 PF13671.1 KKK12749.1 - 3e-23 82.2 0.0 3.8e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KKK12749.1 - 9.5e-05 21.7 0.0 0.00012 21.4 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KKK12749.1 - 0.024 13.7 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin Septin PF00735.13 KKK12750.1 - 6.6e-103 343.5 0.1 1.1e-102 342.8 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KKK12750.1 - 0.00033 20.6 0.0 0.00069 19.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KKK12750.1 - 0.0021 17.9 3.7 0.72 9.6 0.0 2.8 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 KKK12750.1 - 0.0022 17.2 0.1 0.0056 15.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KKK12750.1 - 0.0025 17.2 0.0 0.068 12.5 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 KKK12750.1 - 0.0046 16.5 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK12750.1 - 0.072 13.9 4.1 0.48 11.2 0.1 2.9 2 2 0 2 2 2 0 AAA domain AIG1 PF04548.11 KKK12750.1 - 0.089 11.8 0.1 0.23 10.5 0.1 1.7 1 1 0 1 1 1 0 AIG1 family Miro PF08477.8 KKK12750.1 - 0.11 12.9 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF3653 PF12375.3 KKK12750.1 - 0.21 11.8 2.2 3.7 7.8 0.7 2.6 2 1 0 2 2 2 0 Phage protein Fes1 PF08609.5 KKK12751.1 - 1.1e-35 122.0 6.7 2.2e-34 117.8 3.5 2.3 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KKK12751.1 - 1e-12 48.1 0.6 3.4e-06 27.2 0.0 2.6 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 KKK12751.1 - 3.8e-07 29.6 0.1 0.034 14.2 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.1 KKK12751.1 - 1.9e-06 28.1 0.1 2.9e-05 24.4 0.0 2.5 2 2 1 3 3 3 2 HEAT-like repeat Arm PF00514.18 KKK12751.1 - 1.9e-06 27.4 0.0 0.0017 18.1 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KKK12751.1 - 0.04 12.2 0.1 0.086 11.1 0.0 1.5 1 1 0 1 1 1 0 Adaptin N terminal region AAA_22 PF13401.1 KKK12751.1 - 0.055 13.6 0.0 0.096 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain V-ATPase_H_N PF03224.9 KKK12751.1 - 0.075 12.1 0.0 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H PSD2 PF07624.6 KKK12751.1 - 0.1 12.2 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) Membr_traf_MHD PF10540.4 KKK12753.1 - 5.2e-32 110.5 0.4 2.2e-31 108.4 0.0 2.4 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KKK12753.1 - 3.2e-15 55.7 0.0 8.3e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 KKK12753.1 - 1.3e-06 27.0 5.9 4.7e-06 25.1 2.3 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF810) EF-hand_2 PF09068.6 KKK12753.1 - 0.031 14.3 0.3 0.41 10.7 0.0 2.9 2 0 0 2 2 2 0 EF hand Ribonuc_L-PSP PF01042.16 KKK12754.1 - 1.8e-35 121.3 0.1 2e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PE PF00934.15 KKK12754.1 - 0.11 12.5 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 PE family SNF2_N PF00176.18 KKK12755.1 - 1.2e-74 250.8 0.7 2e-74 250.1 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK12755.1 - 1.2e-14 53.8 0.1 3.2e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK12755.1 - 2.5e-08 33.9 0.0 8.9e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KKK12755.1 - 5.2e-06 26.0 0.0 2.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HSA PF07529.8 KKK12755.1 - 0.00032 20.4 8.9 0.00032 20.4 6.2 2.6 2 0 0 2 2 2 1 HSA DEAD_2 PF06733.10 KKK12755.1 - 0.047 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 FUSC PF04632.7 KKK12755.1 - 1.7 6.9 1.4 3.4 5.9 1.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family NDUF_B8 PF05821.6 KKK12756.1 - 4.6e-08 32.9 0.0 5.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SUR7 PF06687.7 KKK12758.1 - 3.2e-51 173.9 12.9 3.8e-51 173.6 9.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family FAD_binding_4 PF01565.18 KKK12760.1 - 1.4e-24 86.1 3.2 2.3e-24 85.4 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK12760.1 - 0.067 13.1 0.1 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Myb_DNA-binding PF00249.26 KKK12761.1 - 1.4e-11 44.2 2.8 1.9e-09 37.4 0.1 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK12761.1 - 2e-07 30.9 5.1 4.5e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain zf-C2H2_4 PF13894.1 KKK12762.1 - 2.2e-12 46.3 11.0 6.3e-05 23.0 0.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK12762.1 - 8.7e-11 41.5 14.1 0.00048 20.3 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.2 KKK12762.1 - 9e-06 25.7 0.3 0.19 11.9 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KKK12762.1 - 1.4e-05 25.1 11.6 0.05 13.9 2.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KKK12762.1 - 0.0028 17.7 2.2 2.8 8.1 0.0 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KKK12762.1 - 0.13 12.4 4.4 0.38 10.8 0.6 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.2 KKK12762.1 - 1.2 9.1 6.1 9.5 6.2 0.0 2.7 2 1 1 3 3 3 0 Zinc-binding zf-BED PF02892.10 KKK12762.1 - 3.4 7.5 7.7 2.6 7.8 1.4 2.9 1 1 2 3 3 3 0 BED zinc finger Ion_trans PF00520.26 KKK12763.1 - 0.26 10.5 25.5 0.018 14.2 13.3 2.3 2 1 0 2 2 2 0 Ion transport protein Pkinase PF00069.20 KKK12764.1 - 1.2e-23 83.6 0.0 1.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KKK12764.1 - 1.3e-12 46.6 7.4 0.0031 17.4 0.1 6.9 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.27 KKK12764.1 - 1.8e-12 46.6 13.9 1.7e-08 34.0 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.1 KKK12764.1 - 6.3e-09 36.0 3.3 0.13 12.6 0.0 4.6 3 1 1 4 4 4 3 HEAT repeats Pkinase_Tyr PF07714.12 KKK12764.1 - 0.00022 20.3 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KKK12764.1 - 0.00042 20.7 4.8 0.012 16.1 0.4 4.4 5 0 0 5 5 5 1 HEAT-like repeat DUF2454 PF10521.4 KKK12764.1 - 0.0015 17.6 0.3 0.0053 15.7 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2454) DUF2435 PF10363.4 KKK12764.1 - 0.047 13.6 0.2 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Adaptin_N PF01602.15 KKK12764.1 - 0.086 11.1 2.1 2.6 6.2 0.1 2.2 2 0 0 2 2 2 0 Adaptin N terminal region RPA_C PF08784.6 KKK12766.1 - 1.2e-15 57.7 0.3 5.2e-15 55.7 0.0 2.2 3 0 0 3 3 3 1 Replication protein A C terminal HTH_24 PF13412.1 KKK12766.1 - 0.0044 16.3 0.0 0.0092 15.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding tRNA_anti-codon PF01336.20 KKK12766.1 - 0.0055 16.5 0.1 0.017 14.9 0.0 1.8 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain MatE PF01554.13 KKK12767.1 - 1.3e-55 187.4 29.4 1.5e-31 109.2 5.1 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KKK12767.1 - 0.00026 20.8 4.1 0.00026 20.8 2.8 4.1 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.10 KKK12768.1 - 6.9e-21 74.2 0.4 6.9e-21 74.2 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2976 PF11190.3 KKK12768.1 - 0.02 14.4 1.3 0.049 13.1 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) COX4_pro_2 PF07835.7 KKK12768.1 - 0.041 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV GWT1 PF06423.7 KKK12768.1 - 0.063 13.3 0.7 0.087 12.9 0.5 1.2 1 0 0 1 1 1 0 GWT1 Lysis_col PF02402.11 KKK12768.1 - 0.19 11.3 0.9 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Lysis protein Yip1 PF04893.12 KKK12768.1 - 0.26 10.7 6.3 0.19 11.2 2.7 1.8 1 1 1 2 2 2 0 Yip1 domain Ost4 PF10215.4 KKK12768.1 - 9.9 5.7 9.3 0.48 9.9 0.5 2.7 3 0 0 3 3 3 0 Oligosaccaryltransferase NUDIX PF00293.23 KKK12769.1 - 5.7e-28 97.2 0.0 8.7e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DENN PF02141.16 KKK12771.1 - 7.8e-41 139.8 0.1 1.1e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KKK12771.1 - 0.00085 19.2 0.5 0.0032 17.3 0.0 2.2 3 0 0 3 3 3 1 uDENN domain DEAD PF00270.24 KKK12772.1 - 6.6e-45 152.6 0.2 3.6e-44 150.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 KKK12772.1 - 2.1e-21 75.4 1.3 9.1e-21 73.4 0.9 2.2 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 KKK12772.1 - 3.6e-21 74.7 0.1 1.8e-20 72.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK12773.1 - 9.2e-34 116.3 0.0 2.1e-16 59.8 0.0 2.5 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK12773.1 - 3.5e-17 62.0 0.2 8.5e-17 60.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK12773.1 - 3.4e-06 27.0 0.0 3.4e-06 27.0 0.0 3.2 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Nop14 PF04147.7 KKK12773.1 - 2.3e-05 22.5 15.5 2.3e-05 22.5 10.7 2.1 2 0 0 2 2 2 1 Nop14-like family BUD22 PF09073.5 KKK12773.1 - 0.003 16.6 25.2 0.003 16.6 17.4 3.1 2 1 1 3 3 3 1 BUD22 MIP-T3 PF10243.4 KKK12773.1 - 0.97 7.8 57.4 0.71 8.2 7.9 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Fungal_trans PF04082.13 KKK12774.1 - 1.1e-16 60.5 0.1 2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12774.1 - 4.3e-10 39.3 10.5 8e-10 38.4 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_7 PF12775.2 KKK12774.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 MIP-T3 PF10243.4 KKK12774.1 - 0.2 10.1 0.1 0.32 9.4 0.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 YvrJ PF12841.2 KKK12774.1 - 1.2 8.4 3.3 0.6 9.4 0.3 2.0 2 0 0 2 2 2 0 YvrJ protein family TCTP PF00838.12 KKK12775.1 - 4.7e-44 150.2 0.7 5.6e-44 150.0 0.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Ribosomal_S20p PF01649.13 KKK12775.1 - 0.12 12.8 0.2 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 FA_hydroxylase PF04116.8 KKK12776.1 - 5.9e-19 68.5 11.3 5.9e-19 68.5 7.8 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3089 PF11288.3 KKK12777.1 - 0.038 13.1 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) zf-C2H2_4 PF13894.1 KKK12778.1 - 5.1e-08 32.7 9.6 0.056 13.7 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK12778.1 - 3.5e-05 23.8 15.2 0.36 11.2 0.1 3.9 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK12778.1 - 0.013 15.8 13.8 0.027 14.7 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Microtub_assoc PF07989.6 KKK12778.1 - 0.064 13.0 1.3 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Microtubule associated zf-H2C2_5 PF13909.1 KKK12778.1 - 0.21 11.8 3.7 2.5 8.4 0.2 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain SRP19 PF01922.12 KKK12779.1 - 1.1e-31 109.3 0.0 1.6e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Dus PF01207.12 KKK12780.1 - 1.5e-43 148.8 0.0 4.6e-31 107.8 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KKK12780.1 - 0.013 15.1 2.4 2.3 7.9 0.3 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_4 PF13894.1 KKK12781.1 - 1.2e-05 25.2 9.1 0.047 14.0 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK12781.1 - 0.00077 19.6 12.6 0.051 13.9 1.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK12781.1 - 0.0013 18.7 2.2 0.044 13.9 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KKK12781.1 - 0.0082 16.3 0.4 0.0082 16.3 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain SprT-like PF10263.4 KKK12781.1 - 0.022 14.4 0.3 0.038 13.6 0.2 1.3 1 0 0 1 1 1 0 SprT-like family TFIIA PF03153.8 KKK12782.1 - 8.9e-87 292.4 0.4 4e-86 290.2 0.3 1.8 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KKK12782.1 - 0.78 7.9 12.0 1 7.5 8.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GST_C_3 PF14497.1 KKK12783.1 - 2.8e-10 40.5 0.0 4.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KKK12783.1 - 1.7e-05 24.9 0.1 0.00017 21.7 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK12783.1 - 3e-05 23.8 0.1 6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pro_isomerase PF00160.16 KKK12783.1 - 0.022 14.9 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bap31 PF05529.7 KKK12784.1 - 5e-65 218.5 0.3 5.7e-65 218.3 0.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like HALZ PF02183.13 KKK12784.1 - 0.0029 17.2 0.2 0.009 15.7 0.0 1.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper DivIC PF04977.10 KKK12784.1 - 0.0039 16.6 1.2 0.84 9.1 0.0 3.2 3 0 0 3 3 3 2 Septum formation initiator TMF_DNA_bd PF12329.3 KKK12784.1 - 0.056 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1385 PF07136.6 KKK12784.1 - 4 6.4 6.2 5.1 6.0 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) Aminotran_3 PF00202.16 KKK12785.1 - 5e-38 130.7 0.0 9.7e-21 73.9 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 KKK12785.1 - 6.7e-37 127.0 0.0 1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain BATS PF06968.8 KKK12786.1 - 1.2e-28 98.8 0.0 7.7e-28 96.1 0.0 2.2 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KKK12786.1 - 6.5e-16 58.9 0.0 3.4e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Cation_ATPase_C PF00689.16 KKK12787.1 - 3.3e-33 114.7 10.9 3.3e-33 114.7 7.6 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.15 KKK12787.1 - 1.3e-29 102.9 0.4 2.4e-29 102.0 0.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KKK12787.1 - 1.3e-29 104.1 0.0 4.1e-29 102.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK12787.1 - 1.8e-16 59.8 0.0 4.3e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK12787.1 - 2.9e-13 50.4 0.0 9e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK12787.1 - 0.00019 21.0 0.2 0.014 14.9 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.16 KKK12788.1 - 4.6e-38 131.0 0.0 5.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 KKK12788.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.15 KKK12788.1 - 0.0055 15.0 0.0 0.0071 14.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 KKK12788.1 - 0.022 13.2 0.0 0.064 11.7 0.0 1.6 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DUF952 PF06108.7 KKK12789.1 - 5.2e-26 90.3 0.0 6.2e-26 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) IMPDH PF00478.20 KKK12790.1 - 1.4e-129 431.9 2.6 1.7e-129 431.7 1.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KKK12790.1 - 8.1e-20 70.3 0.0 1.8e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KKK12790.1 - 1.4e-06 27.6 2.9 0.011 14.9 2.0 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KKK12790.1 - 4.5e-05 22.4 0.5 0.00014 20.8 0.3 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KKK12790.1 - 0.00065 19.0 2.4 0.005 16.1 1.7 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein DUF1273 PF06908.6 KKK12790.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) RasGAP_C PF03836.10 KKK12791.1 - 9.4e-49 164.7 4.6 9.4e-49 164.7 3.2 3.0 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 KKK12791.1 - 8.6e-43 146.3 0.0 3.2e-42 144.4 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 KKK12791.1 - 5.9e-10 39.1 0.0 5e-09 36.1 0.0 2.6 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 KKK12791.1 - 1.7e-06 27.1 53.6 0.34 10.6 0.7 14.7 16 0 0 16 16 16 4 IQ calmodulin-binding motif ENTH PF01417.15 KKK12792.1 - 5.1e-46 155.6 0.1 7.2e-46 155.1 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KKK12792.1 - 1.6e-05 23.7 0.0 2.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 KKK12792.1 - 0.044 13.4 0.1 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 VHS domain Velvet PF11754.3 KKK12807.1 - 3.4e-63 212.9 0.0 5.5e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Peptidase_M13_N PF05649.8 KKK12809.1 - 2.3e-90 303.4 0.0 3.2e-90 302.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KKK12809.1 - 5.5e-51 172.6 0.0 9.3e-51 171.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 p450 PF00067.17 KKK12844.1 - 2.2e-19 69.3 0.0 2.6e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KKK12851.1 - 1.7e-14 53.3 1.5 2.6e-14 52.7 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12851.1 - 2.8e-07 30.3 11.5 6.3e-07 29.2 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.26 KKK12852.1 - 2.6e-17 62.2 0.6 3.7e-17 61.7 0.1 1.5 2 0 0 2 2 2 1 DnaJ domain UPF0029 PF01205.14 KKK12853.1 - 1.1e-28 99.1 0.1 2.6e-28 97.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KKK12853.1 - 1e-07 31.8 0.4 1.8e-07 31.0 0.3 1.4 1 0 0 1 1 1 1 RWD domain Tetraspannin PF00335.15 KKK12854.1 - 0.25 10.5 2.7 1.7 7.8 0.2 2.4 2 0 0 2 2 2 0 Tetraspanin family Chitin_bind_3 PF03067.10 KKK12855.1 - 8.7e-07 29.3 0.0 1.7e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Chitin binding domain CTF_NFI PF00859.13 KKK12855.1 - 0.00066 19.5 7.7 0.0015 18.3 5.4 1.7 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region Glyco_hydro_61 PF03443.9 KKK12855.1 - 0.0073 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ribosomal_L4 PF00573.17 KKK12856.1 - 1.1e-42 145.5 0.7 1.5e-42 145.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KKK12856.1 - 3.1e-31 107.0 1.1 7.9e-31 105.7 0.7 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain LCCL PF03815.14 KKK12857.1 - 1.9e-23 82.2 0.2 3.1e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.16 KKK12858.1 - 5e-05 22.4 0.0 9.1e-05 21.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II TauD PF02668.11 KKK12866.1 - 8.6e-58 196.0 0.1 1.2e-57 195.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KKK12866.1 - 0.0014 17.6 0.0 0.0026 16.7 0.0 1.5 1 1 0 1 1 1 1 CsiD DUF971 PF06155.7 KKK12866.1 - 0.017 15.5 0.1 0.044 14.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 KKK12866.1 - 0.032 14.7 0.0 0.1 13.1 0.0 1.8 1 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Ponericin PF07442.6 KKK12866.1 - 7.4 6.4 5.7 3.3 7.6 0.9 2.2 2 0 0 2 2 2 0 Ponericin Inositol_P PF00459.20 KKK12867.1 - 3.9e-80 269.0 0.0 4.5e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.14 KKK12868.1 - 3.7e-62 207.7 0.1 4.3e-62 207.5 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II CFEM PF05730.6 KKK12869.1 - 2.1e-15 56.2 11.5 3.5e-15 55.5 8.0 1.4 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.4 KKK12869.1 - 2 7.0 13.8 2.2 6.8 9.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF566 PF04484.7 KKK12869.1 - 2.2 7.7 10.0 2.5 7.5 7.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pex14_N PF04695.8 KKK12869.1 - 2.5 8.1 8.5 4.3 7.3 5.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 KKK12869.1 - 7.3 5.8 11.9 8.9 5.5 8.3 1.1 1 0 0 1 1 1 0 Vta1 like zf-C3HC4_3 PF13920.1 KKK12870.1 - 7.3e-09 35.1 11.7 1.2e-08 34.4 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Arrestin_C PF02752.17 KKK12871.1 - 1.7e-14 54.1 0.0 7.9e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DNA_pol_delta_4 PF04081.8 KKK12872.1 - 5.8e-27 94.4 0.1 8.7e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 NADPH_Ox PF08414.5 KKK12872.1 - 0.12 12.4 0.1 2 8.5 0.1 2.2 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase DUF1525 PF07511.6 KKK12872.1 - 0.15 12.0 0.9 0.24 11.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) Pkinase PF00069.20 KKK12874.1 - 2.1e-16 59.8 0.0 1.4e-15 57.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12874.1 - 1.6e-12 47.0 0.0 5.2e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK12874.1 - 0.076 11.9 0.1 0.24 10.3 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 KKK12874.1 - 0.099 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YccV-like PF08755.6 KKK12880.1 - 1.1e-22 79.8 0.0 3.8e-22 78.1 0.0 1.9 2 1 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 KKK12880.1 - 1.4e-09 37.6 0.0 3.3e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Transglutaminase-like superfamily Sugar_tr PF00083.19 KKK12881.1 - 8.1e-105 350.9 29.2 9.3e-105 350.7 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK12881.1 - 1.3e-22 80.0 34.5 3.2e-16 59.0 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK12881.1 - 0.003 16.0 3.6 0.003 16.0 2.5 3.3 1 1 1 3 3 3 2 MFS/sugar transport protein Glyco_hydro_92 PF07971.7 KKK12882.1 - 8.4e-27 93.9 0.1 9.3e-27 93.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 PCI_Csn8 PF10075.4 KKK12883.1 - 2e-46 157.3 0.0 2.6e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KKK12883.1 - 2.9e-24 85.7 0.4 3.9e-24 85.3 0.3 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family LisH PF08513.6 KKK12892.1 - 2.6e-05 23.7 0.2 5.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 LisH Septin PF00735.13 KKK12897.1 - 6.1e-112 373.2 0.7 6.1e-112 373.2 0.5 1.3 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KKK12897.1 - 3.5e-07 30.1 0.0 7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK12897.1 - 5.8e-07 29.1 0.5 1.5e-05 24.5 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KKK12897.1 - 1.8e-05 24.0 0.0 4.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK12897.1 - 0.0023 18.0 0.2 0.0056 16.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KKK12897.1 - 0.003 17.1 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain IIGP PF05049.8 KKK12897.1 - 0.0052 15.6 0.0 0.01 14.6 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 KKK12897.1 - 0.0061 17.0 0.5 0.015 15.7 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein AIG1 PF04548.11 KKK12897.1 - 0.0074 15.4 0.3 0.018 14.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family FtsK_SpoIIIE PF01580.13 KKK12897.1 - 0.0086 15.5 0.1 0.02 14.3 0.1 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 KKK12897.1 - 0.014 14.6 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.22 KKK12897.1 - 0.02 15.1 0.2 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.9 KKK12897.1 - 0.024 13.6 0.1 0.042 12.8 0.1 1.5 1 1 0 1 1 1 0 KAP family P-loop domain DUF3891 PF13030.1 KKK12897.1 - 0.029 13.8 2.7 0.2 11.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3891) Ras PF00071.17 KKK12897.1 - 0.039 13.3 0.8 0.11 11.8 0.3 1.9 2 1 0 2 2 2 0 Ras family NACHT PF05729.7 KKK12897.1 - 0.039 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.18 KKK12897.1 - 0.047 13.5 5.8 0.86 9.3 0.1 3.0 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.4 KKK12897.1 - 0.054 12.9 0.9 2.5 7.5 0.2 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KKK12897.1 - 0.061 13.0 0.1 0.061 13.0 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 KKK12897.1 - 0.064 13.2 0.5 0.31 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 KKK12897.1 - 0.13 11.7 1.1 8.5 5.8 0.1 2.7 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Atg14 PF10186.4 KKK12897.1 - 0.32 9.8 5.0 0.6 8.9 3.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KKK12897.1 - 0.41 10.2 3.2 0.76 9.3 2.2 1.5 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 KKK12897.1 - 0.47 10.7 15.7 5.6 7.2 10.9 2.0 1 1 0 1 1 1 0 AAA domain Myc-LZ PF02344.10 KKK12897.1 - 0.58 9.8 5.2 0.89 9.2 0.3 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.27 KKK12898.1 - 2.8e-37 125.2 13.8 3.8e-06 26.5 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ PF01011.16 KKK12898.1 - 0.00058 19.2 0.1 0.013 14.9 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat VID27 PF08553.5 KKK12898.1 - 0.0085 14.3 0.0 0.012 13.8 0.0 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein UPF0180 PF03698.8 KKK12898.1 - 0.057 13.2 0.0 41 4.1 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) p450 PF00067.17 KKK12899.1 - 8.9e-34 116.7 0.0 1.1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KKK12900.1 - 1.6e-52 173.5 31.0 2.7e-12 46.0 0.0 12.4 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 KKK12900.1 - 5.2e-28 97.1 0.0 7.9e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KKK12900.1 - 1.3e-06 28.2 0.2 0.0021 17.8 0.1 4.9 5 1 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KKK12900.1 - 5.9e-06 24.6 6.2 0.074 11.1 0.0 4.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 KKK12900.1 - 0.024 13.7 0.1 9.1 5.2 0.0 3.2 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 KKK12900.1 - 0.062 12.1 0.4 1.4 7.7 0.0 3.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1513) WD40 PF00400.27 KKK12901.1 - 4.5e-44 146.8 2.8 7.2e-09 35.1 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KKK12901.1 - 9.8e-30 102.2 0.9 2e-29 101.3 0.6 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 KKK12901.1 - 0.0072 14.5 4.0 0.37 8.8 0.1 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 XRN_N PF03159.13 KKK12902.1 - 1.2e-102 342.2 0.1 1.2e-102 342.2 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus R3H PF01424.17 KKK12902.1 - 0.002 17.7 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 1 R3H domain GTP_cyclohydroI PF01227.17 KKK12903.1 - 1.3e-73 246.1 0.2 1.6e-73 245.7 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KKK12903.1 - 0.004 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Endosulfine PF04667.12 KKK12904.1 - 3.8e-22 78.0 0.0 5.6e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region PhyH PF05721.8 KKK12905.1 - 2.4e-27 96.3 0.0 2.9e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KKK12905.1 - 0.018 15.3 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase TauD PF02668.11 KKK12905.1 - 0.02 14.5 0.0 0.13 11.9 0.0 2.0 1 1 1 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family DUF1479 PF07350.7 KKK12905.1 - 0.058 11.8 0.0 0.11 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) NmrA PF05368.8 KKK12906.1 - 3.1e-34 118.2 0.0 4.3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK12906.1 - 2.8e-13 50.2 0.1 4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KKK12906.1 - 5.6e-06 25.5 0.1 7e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KKK12906.1 - 0.00051 20.3 0.1 0.0019 18.5 0.0 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK12906.1 - 0.00098 19.5 0.2 0.009 16.4 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 KKK12906.1 - 0.011 15.3 0.5 0.023 14.3 0.3 1.6 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 KKK12906.1 - 0.02 14.8 0.6 0.035 14.0 0.3 1.6 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 KKK12906.1 - 0.026 14.4 0.1 0.048 13.5 0.1 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 KKK12906.1 - 0.041 13.8 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 KKK12906.1 - 0.097 11.3 0.1 0.2 10.3 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RRM_1 PF00076.17 KKK12907.1 - 4.7e-09 35.7 0.0 1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK12907.1 - 1.2e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK12907.1 - 1.9e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK12907.1 - 0.0069 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TPR_10 PF13374.1 KKK12907.1 - 0.73 9.8 3.5 2.6 8.0 2.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Cut12 PF11500.3 KKK12908.1 - 4.8e-50 169.1 16.5 4.8e-50 169.1 11.5 3.9 3 1 2 5 5 5 1 Spindle pole body formation-associated protein Glutaredoxin2_C PF04399.8 KKK12908.1 - 2.3 7.8 14.8 0.17 11.4 1.4 3.3 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain HGTP_anticodon2 PF12745.2 KKK12909.1 - 5.1e-83 278.3 0.4 5.1e-83 278.3 0.3 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 KKK12909.1 - 4.7e-68 229.1 0.0 5.8e-37 127.2 0.0 4.8 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12909.1 - 3.1e-41 141.1 0.0 7.1e-19 67.8 0.0 3.6 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 KKK12909.1 - 3.6e-16 59.0 0.1 7.9e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 KKK12909.1 - 2.2e-11 43.3 0.1 7.9e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 KKK12909.1 - 8.8e-05 21.5 0.0 0.17 10.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KKK12909.1 - 0.00012 21.8 1.5 0.0012 18.5 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family adh_short_C2 PF13561.1 KKK12910.1 - 2.8e-24 86.2 0.5 3.1e-24 86.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK12910.1 - 2.3e-11 43.9 0.1 3.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK12910.1 - 8.3e-06 25.5 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK12910.1 - 1.6e-05 24.9 0.4 5.2e-05 23.3 0.2 1.8 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_7 PF13241.1 KKK12910.1 - 0.003 17.8 0.1 0.0087 16.2 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 KKK12910.1 - 0.033 13.2 0.6 0.11 11.6 0.0 2.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KKK12910.1 - 0.049 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KKK12910.1 - 0.064 13.0 0.3 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_tran_WecB PF03808.8 KKK12910.1 - 0.099 12.0 0.0 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family FAD_binding_3 PF01494.14 KKK12911.1 - 8.8e-18 64.4 1.1 2.7e-16 59.5 0.7 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK12911.1 - 3.4e-11 42.6 4.0 8.5e-06 24.8 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK12911.1 - 2.4e-06 26.6 0.4 4.5e-06 25.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK12911.1 - 0.0017 18.3 1.1 0.011 15.6 0.7 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK12911.1 - 0.0019 16.7 0.2 0.0078 14.7 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KKK12911.1 - 0.0031 17.5 0.4 0.0088 16.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KKK12911.1 - 0.0065 15.5 0.1 0.008 15.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KKK12911.1 - 0.0098 14.7 0.2 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DUF4434 PF14488.1 KKK12911.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) BRCA-2_OB3 PF09104.5 KKK12911.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Lycopene_cycl PF05834.7 KKK12911.1 - 0.29 10.0 1.0 5.3 5.8 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_DMAT PF11991.3 KKK12912.1 - 8.5e-97 324.5 0.0 1.1e-96 324.2 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF1769 PF08588.5 KKK12912.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Methyltransf_31 PF13847.1 KKK12913.1 - 7.4e-10 38.6 0.0 1.8e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK12913.1 - 1.2e-07 31.9 0.1 2.6e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK12913.1 - 1.6e-06 28.5 0.1 7.5e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK12913.1 - 8.8e-06 26.2 0.3 1.9e-05 25.1 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK12913.1 - 1.7e-05 24.6 0.0 3.6e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK12913.1 - 9.2e-05 22.8 0.1 0.00033 21.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 KKK12913.1 - 0.00052 19.3 0.0 0.00076 18.8 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 KKK12913.1 - 0.00055 19.9 0.2 0.001 19.0 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK12913.1 - 0.051 12.6 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KKK12913.1 - 0.054 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 KKK12914.1 - 3.3e-38 131.3 0.0 9.9e-21 73.7 0.0 3.1 1 1 2 3 3 3 3 Cytochrome P450 NmrA PF05368.8 KKK12915.1 - 1.8e-27 96.1 0.0 2.6e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK12915.1 - 3.7e-12 46.6 0.1 5.5e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KKK12915.1 - 0.0094 15.6 0.4 0.017 14.8 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KKK12915.1 - 0.094 12.6 0.8 0.17 11.7 0.3 1.6 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 KKK12915.1 - 0.16 11.9 0.2 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus p450 PF00067.17 KKK12916.1 - 4.3e-42 144.2 0.0 5.7e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ERbeta_N PF12497.3 KKK12916.1 - 0.063 13.1 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Estrogen receptor beta p450 PF00067.17 KKK12917.1 - 1.7e-41 142.2 0.0 4.1e-41 140.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KKK12918.1 - 6.7e-157 522.1 0.2 3.4e-79 266.2 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 KKK12918.1 - 5.3e-42 143.4 0.0 1e-41 142.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.15 KKK12918.1 - 2.8e-36 124.9 0.0 9.3e-36 123.2 0.0 1.9 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.20 KKK12918.1 - 5.8e-16 58.5 0.4 1.1e-06 28.8 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK12918.1 - 6.4e-09 36.6 0.1 9.7e-05 23.2 0.1 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KKK12918.1 - 1.7e-08 34.1 0.1 1.3e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KKK12918.1 - 0.01 14.7 0.0 4.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KKK12918.1 - 0.018 15.0 0.3 0.54 10.2 0.1 2.7 2 0 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 KKK12918.1 - 0.06 12.0 0.1 0.19 10.3 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF89 PF01937.14 KKK12919.1 - 2.5e-137 457.4 0.0 2.9e-137 457.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CRF PF00473.12 KKK12919.1 - 0.11 12.5 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Corticotropin-releasing factor family PhyH PF05721.8 KKK12920.1 - 7.2e-23 81.7 0.0 1e-22 81.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KKK12920.1 - 1.3e-06 27.2 0.0 4e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) Trp_DMAT PF11991.3 KKK12921.1 - 3.3e-85 286.4 0.0 4.6e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 KKK12922.1 - 1.7e-24 86.1 0.0 3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 KKK12923.1 - 2.3e-32 112.1 0.0 3.3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK12923.1 - 3.6e-07 30.3 0.4 5.6e-07 29.7 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK12923.1 - 0.00076 18.2 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KKK12923.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain PhyH PF05721.8 KKK12924.1 - 5.6e-21 75.5 0.1 1e-20 74.6 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KKK12924.1 - 0.00019 20.0 0.0 0.00067 18.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) FAD_binding_4 PF01565.18 KKK12925.1 - 9.3e-18 64.0 4.2 3.1e-17 62.3 2.9 1.9 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK12925.1 - 1.1e-05 25.2 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like NmrA PF05368.8 KKK12926.1 - 4.4e-29 101.3 0.0 6.3e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK12926.1 - 5.8e-14 52.4 0.0 8.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK12926.1 - 1.2e-05 24.1 0.0 2.6e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KKK12926.1 - 0.0045 17.3 0.2 0.024 15.0 0.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 KKK12926.1 - 0.0061 15.5 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 KKK12926.1 - 0.008 16.1 0.1 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain Epimerase PF01370.16 KKK12926.1 - 0.02 14.3 0.0 0.039 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK12926.1 - 0.079 12.6 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 KR domain AAA PF00004.24 KKK12927.1 - 3.2e-43 147.0 0.0 9.3e-43 145.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KKK12927.1 - 1.2e-12 47.9 0.1 2.8e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 KKK12927.1 - 4.8e-05 23.1 0.0 0.00016 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KKK12927.1 - 0.0002 21.4 0.0 0.15 12.1 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KKK12927.1 - 0.0036 18.1 0.0 0.008 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KKK12927.1 - 0.0053 15.5 0.1 0.0089 14.7 0.1 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KKK12927.1 - 0.0082 16.1 0.3 0.13 12.2 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF935 PF06074.7 KKK12927.1 - 0.0087 14.8 0.2 0.0087 14.8 0.2 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF935) RuvB_N PF05496.7 KKK12927.1 - 0.0097 14.9 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK12927.1 - 0.017 14.8 0.8 0.017 14.8 0.6 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 KKK12927.1 - 0.02 14.8 0.0 0.054 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KKK12927.1 - 0.027 14.4 0.0 0.098 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KKK12927.1 - 0.032 13.6 0.2 0.07 12.5 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 KKK12927.1 - 0.036 13.9 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KKK12927.1 - 0.044 13.1 0.8 0.14 11.5 0.3 1.9 1 1 1 2 2 2 0 AAA domain Serinc PF03348.10 KKK12927.1 - 0.11 11.2 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_11 PF13086.1 KKK12927.1 - 0.13 11.8 0.8 11 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain fn3 PF00041.16 KKK12934.1 - 3.4e-06 27.1 0.0 9e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain LNS2 PF08235.8 KKK12935.1 - 8.1e-71 236.6 0.0 1.4e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KKK12935.1 - 5.3e-41 138.7 0.0 2.5e-40 136.5 0.0 2.0 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KKK12935.1 - 0.0022 17.3 0.0 0.21 10.9 0.0 2.8 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) CobT PF06213.7 KKK12935.1 - 0.37 9.8 7.0 0.59 9.2 4.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AF1Q PF15017.1 KKK12935.1 - 0.48 10.3 6.6 1.1 9.1 4.6 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Thg1C PF14413.1 KKK12936.1 - 1.9e-54 182.4 1.1 2.7e-54 181.9 0.8 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KKK12936.1 - 6.4e-30 103.5 0.0 5.5e-27 94.0 0.0 2.9 1 1 0 1 1 1 1 tRNAHis guanylyltransferase DUF1319 PF07028.6 KKK12936.1 - 0.06 13.5 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) ATP-synt_E PF05680.7 KKK12937.1 - 0.012 15.5 2.9 0.012 15.5 2.0 2.6 2 1 0 2 2 2 0 ATP synthase E chain AAA_23 PF13476.1 KKK12937.1 - 0.074 13.3 20.4 0.1 12.9 14.2 1.2 1 0 0 1 1 1 0 AAA domain Hex_IIIa PF02455.11 KKK12937.1 - 9.2 4.8 18.7 11 4.6 13.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) HSP70 PF00012.15 KKK12939.1 - 0.081 10.8 0.0 0.12 10.2 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein IF4E PF01652.13 KKK12941.1 - 6.6e-59 198.1 0.0 8.3e-59 197.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RIIa PF02197.12 KKK12941.1 - 0.045 13.1 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit p450 PF00067.17 KKK12942.1 - 2.5e-42 144.9 0.0 4.4e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S5 PF00333.15 KKK12943.1 - 3.2e-28 97.2 3.1 5.4e-28 96.5 1.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KKK12943.1 - 9.4e-21 72.8 0.0 1.8e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FXR1P_C PF12235.3 KKK12943.1 - 0.97 9.5 9.3 1.8 8.6 6.4 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal FoP_duplication PF13865.1 KKK12943.1 - 5.1 7.6 12.0 12 6.4 8.3 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Mpv17_PMP22 PF04117.7 KKK12944.1 - 5.6e-24 83.5 1.4 9.4e-24 82.8 0.9 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Peptidase_C12 PF01088.16 KKK12956.1 - 2.5e-63 213.1 0.0 5.5e-63 211.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Kei1 PF08552.6 KKK12956.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4414 PF14377.1 KKK12956.1 - 0.81 9.6 5.3 32 4.4 3.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) Choline_kinase PF01633.15 KKK12957.1 - 2.7e-59 200.2 0.0 5.8e-59 199.1 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KKK12957.1 - 3.1e-15 55.3 0.0 7.2e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 KKK12957.1 - 5.8e-08 32.7 0.6 1.6e-07 31.3 0.4 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KKK12958.1 - 1.1e-50 172.2 0.0 3.3e-49 167.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12958.1 - 3.6e-31 108.1 0.0 2e-30 105.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KKK12958.1 - 0.0036 16.1 0.1 0.0069 15.2 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 KKK12958.1 - 0.0049 15.8 0.0 0.0076 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KKK12958.1 - 0.089 11.5 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pyr_redox_2 PF07992.9 KKK12959.1 - 3.2e-36 125.1 0.3 3.8e-36 124.8 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK12959.1 - 5.7e-14 52.2 0.5 1.2e-13 51.2 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK12959.1 - 0.00017 21.7 0.0 0.00033 20.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK12959.1 - 0.00019 20.4 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 KKK12959.1 - 0.0002 21.0 0.5 0.00034 20.3 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KKK12959.1 - 0.41 9.4 5.8 1.3 7.8 0.4 2.7 3 1 0 3 3 3 0 Glucose inhibited division protein A Zn_clus PF00172.13 KKK12960.1 - 5.5e-08 32.5 13.2 5.5e-08 32.5 9.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mem_trans PF03547.13 KKK12961.1 - 1.5e-56 191.3 0.1 1.9e-56 191.0 0.1 1.1 1 0 0 1 1 1 1 Membrane transport protein NODP PF07684.7 KKK12961.1 - 0.053 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 NOTCH protein adh_short_C2 PF13561.1 KKK12962.1 - 2.7e-28 99.3 0.0 3.3e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK12962.1 - 8.8e-27 94.0 1.1 1.1e-26 93.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK12962.1 - 8.4e-14 51.6 0.4 1.2e-13 51.1 0.2 1.1 1 0 0 1 1 1 1 KR domain Alk_phosphatase PF00245.15 KKK12962.1 - 0.034 12.8 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase BIR PF00653.16 KKK12967.1 - 2.9e-41 139.7 6.4 8.1e-22 77.4 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Mmp37 PF09139.6 KKK12968.1 - 2.2e-140 467.3 0.0 2.7e-140 467.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 TP_methylase PF00590.15 KKK12969.1 - 1.2e-21 77.3 0.1 2.1e-21 76.6 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.11 KKK12970.1 - 1.6e-29 101.5 0.3 2.7e-28 97.6 0.1 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit F-box-like PF12937.2 KKK12971.1 - 3.1e-05 23.6 0.0 5.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK12971.1 - 4.3e-05 23.0 1.3 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 KKK12971.1 - 0.06 13.0 0.4 0.097 12.3 0.0 1.5 2 0 0 2 2 2 0 F-box-like domain zf-C2H2_jaz PF12171.3 KKK12972.1 - 6.2e-08 32.5 0.1 1.1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK12972.1 - 6.3e-06 26.2 0.2 1.1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KKK12972.1 - 0.0016 18.6 0.4 0.0031 17.7 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KKK12972.1 - 0.042 13.9 0.3 0.24 11.5 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) MAP7 PF05672.6 KKK12972.1 - 0.57 9.5 29.0 1.6 8.1 0.8 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family CAF-1_p150 PF11600.3 KKK12972.1 - 2.8 7.2 25.7 1.4 8.1 13.2 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sulfotransfer_3 PF13469.1 KKK12973.1 - 0.00017 22.5 0.8 0.00024 22.0 0.4 1.4 1 1 0 1 1 1 1 Sulfotransferase family Arylsulfotran_2 PF14269.1 KKK12974.1 - 1.1e-54 185.6 6.7 1.8e-54 184.9 4.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KKK12974.1 - 4.3e-20 71.6 6.5 5.8e-19 67.9 4.5 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Clat_adaptor_s PF01217.15 KKK12976.1 - 5.9e-51 171.9 3.0 3.6e-50 169.3 2.1 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain LRR_9 PF14580.1 KKK13028.1 - 4.1e-52 176.2 0.1 4.1e-52 176.2 0.0 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 KKK13028.1 - 9.4e-09 34.7 4.1 0.0035 16.9 0.8 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK13028.1 - 1.2e-07 31.3 7.9 2.8e-05 23.7 1.4 2.7 2 1 1 3 3 3 2 Leucine rich repeat HTH_38 PF13936.1 KKK13028.1 - 0.073 12.6 1.8 0.11 12.0 0.6 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4349 PF14257.1 KKK13028.1 - 0.25 10.5 1.8 0.41 9.8 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) GDA1_CD39 PF01150.12 KKK13029.1 - 2.8e-97 325.9 0.0 1.3e-51 175.5 0.0 2.1 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ammonium_transp PF00909.16 KKK13030.1 - 5.4e-107 357.7 23.2 6.9e-107 357.3 16.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MFS_1 PF07690.11 KKK13031.1 - 6.9e-29 100.6 33.3 1.3e-17 63.5 19.3 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2109 PF09882.4 KKK13031.1 - 1.8 8.5 6.8 0.52 10.2 1.2 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Acyltransferase PF01553.16 KKK13032.1 - 1.4e-17 63.3 0.0 3.2e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase HxlR PF01638.12 KKK13032.1 - 0.0097 15.5 0.1 0.47 10.1 0.1 3.1 2 0 0 2 2 2 1 HxlR-like helix-turn-helix Pantoate_ligase PF02569.10 KKK13033.1 - 1.5e-80 269.9 0.0 3e-80 268.9 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.24 KKK13034.1 - 5.2e-40 136.6 0.0 8.2e-40 136.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KKK13034.1 - 1.1e-20 72.8 0.0 2.3e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KKK13034.1 - 6.9e-20 70.6 0.0 1.5e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK13034.1 - 0.0011 18.7 0.3 0.0028 17.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Neur_chan_memb PF02932.11 KKK13034.1 - 0.54 10.0 2.1 1.3 8.8 0.7 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Fungal_trans_2 PF11951.3 KKK13035.1 - 2.1e-07 29.9 0.1 4.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 KKK13035.1 - 5.1e-06 26.1 5.2 0.058 13.3 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Zn_clus PF00172.13 KKK13035.1 - 2.1e-05 24.3 10.9 4.3e-05 23.3 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAXNEB PF05625.6 KKK13036.1 - 1.2e-128 428.9 0.0 1.4e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.10 KKK13037.1 - 1.8e-36 125.3 0.0 2.1e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NUDIX PF00293.23 KKK13038.1 - 1.8e-11 43.7 0.0 2.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF775 PF05603.7 KKK13039.1 - 4.8e-66 222.1 0.1 5.4e-66 221.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) FYVE_2 PF02318.11 KKK13040.1 - 0.73 9.7 20.5 0.36 10.7 1.9 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger SNF2_N PF00176.18 KKK13041.1 - 2.2e-62 210.5 0.3 3.4e-62 209.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK13041.1 - 1.1e-10 41.2 0.0 1.9e-08 34.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK13041.1 - 3.1e-07 30.0 0.0 6.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KKK13041.1 - 5.2e-07 29.6 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KKK13041.1 - 4.8e-05 22.3 0.0 9e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 KKK13041.1 - 0.072 12.7 16.7 0.12 12.1 6.2 2.5 1 1 1 2 2 2 0 PHD-finger zf-UDP PF14569.1 KKK13041.1 - 0.48 10.2 4.7 0.29 10.9 1.6 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger C1_3 PF07649.7 KKK13041.1 - 8.9 6.4 19.0 0.43 10.6 4.9 2.7 2 0 0 2 2 2 0 C1-like domain UPF0086 PF01868.11 KKK13042.1 - 1.3e-31 108.1 0.1 2.4e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF2073 PF09846.4 KKK13042.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) tRNA_int_endo PF01974.12 KKK13043.1 - 1.8e-15 56.4 0.0 3.2e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF1943 PF09172.6 KKK13043.1 - 0.052 12.4 3.2 0.076 11.8 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Autophagy_N PF03986.8 KKK13043.1 - 0.34 10.6 3.2 0.53 10.0 2.2 1.2 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF3340 PF11818.3 KKK13043.1 - 0.48 10.3 7.8 0.75 9.7 5.4 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) GATase PF00117.23 KKK13044.1 - 1.2e-11 44.4 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KKK13044.1 - 0.018 14.4 0.6 0.38 10.1 0.4 2.7 1 1 0 1 1 1 0 Peptidase C26 MFS_1 PF07690.11 KKK13045.1 - 6.8e-42 143.4 38.5 6.8e-42 143.4 26.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK13045.1 - 3.3e-09 35.8 15.5 3.3e-09 35.8 10.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KKK13045.1 - 2.9e-07 29.0 19.2 4.4e-07 28.4 13.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_L22 PF00237.14 KKK13046.1 - 2.1e-24 85.4 0.1 3.7e-24 84.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Pectate_lyase_3 PF12708.2 KKK13047.1 - 5.4e-89 298.1 14.8 1.3e-70 238.0 8.5 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KKK13047.1 - 5e-06 25.8 1.6 0.042 13.3 0.2 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase NosD PF05048.8 KKK13047.1 - 0.00014 21.1 2.7 0.00037 19.7 1.9 1.7 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Aminotran_1_2 PF00155.16 KKK13048.1 - 2.7e-17 62.7 0.0 3.3e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CAP18_C PF12153.3 KKK13048.1 - 0.1 12.2 0.5 0.24 11.0 0.3 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) GAT PF03127.9 KKK13049.1 - 9.9e-15 54.3 1.0 1.5e-14 53.7 0.1 1.7 2 0 0 2 2 2 1 GAT domain Sirohm_synth_M PF14824.1 KKK13049.1 - 0.12 11.4 0.1 0.23 10.4 0.1 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central PIH1 PF08190.7 KKK13049.1 - 0.38 10.1 6.9 1.7 8.0 0.1 2.2 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 Chitin_bind_3 PF03067.10 KKK13050.1 - 2.4e-17 63.8 0.7 2.4e-17 63.8 0.5 2.1 2 0 0 2 2 2 1 Chitin binding domain Med3 PF11593.3 KKK13050.1 - 2.9 7.0 37.8 5.2 6.1 26.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Transket_pyr PF02779.19 KKK13052.1 - 1.7e-64 216.5 0.0 3.3e-64 215.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KKK13052.1 - 1.3e-56 191.5 0.0 1.8e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Microtub_assoc PF07989.6 KKK13053.1 - 0.0024 17.6 0.9 0.0024 17.6 0.6 2.5 1 1 1 2 2 2 1 Microtubule associated AAA_23 PF13476.1 KKK13053.1 - 1.9 8.7 11.3 3.2 8.0 7.8 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KKK13053.1 - 2 5.6 16.2 2.8 5.1 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 KKK13053.1 - 2 8.7 8.3 6.1 7.2 5.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 KKK13053.1 - 3.7 7.5 5.7 16 5.5 3.6 2.3 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KKK13053.1 - 6 6.4 19.9 11 5.5 13.8 1.4 1 0 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 KKK13053.1 - 8.9 6.5 8.3 26 5.0 5.2 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sld5 PF05916.6 KKK13055.1 - 4.3e-16 59.1 0.0 5.5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein tRNA-synt_2 PF00152.15 KKK13058.1 - 5.6e-69 232.4 0.0 7.3e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KKK13058.1 - 5.5e-12 45.1 0.0 8.1e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 KKK13058.1 - 0.0011 18.2 0.2 0.049 12.8 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 KKK13058.1 - 0.0023 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KKK13058.1 - 0.12 11.8 0.0 22 4.5 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) Pyr_redox_2 PF07992.9 KKK13059.1 - 4.5e-21 75.6 2.7 1.6e-09 37.9 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK13059.1 - 2e-19 69.7 1.7 4.2e-15 55.9 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.15 KKK13059.1 - 4.6e-12 46.2 0.0 1.5e-11 44.6 0.0 1.9 2 0 0 2 2 1 1 Rhodanese-like domain FAD_binding_2 PF00890.19 KKK13059.1 - 7.7e-08 31.5 2.1 0.00027 19.9 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KKK13059.1 - 1.1e-06 27.8 5.3 0.0093 14.9 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK13059.1 - 1.2e-06 28.4 4.5 0.012 15.5 0.3 3.1 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 KKK13059.1 - 2e-06 27.5 0.7 0.00038 20.0 0.0 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 KKK13059.1 - 6.7e-05 21.9 6.7 0.6 8.9 0.2 3.4 2 1 1 3 3 3 3 Lycopene cyclase protein Pyr_redox_dim PF02852.17 KKK13059.1 - 8.5e-05 22.5 0.0 0.00032 20.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain XdhC_C PF13478.1 KKK13059.1 - 0.00026 21.2 0.1 0.11 12.8 0.0 2.6 2 0 0 2 2 2 1 XdhC Rossmann domain TrkA_N PF02254.13 KKK13059.1 - 0.00032 20.6 0.6 0.0039 17.1 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.9 KKK13059.1 - 0.00054 18.5 9.0 0.096 11.1 0.3 3.4 2 1 1 3 3 3 2 HI0933-like protein NAD_binding_7 PF13241.1 KKK13059.1 - 0.0016 18.6 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 KKK13059.1 - 0.0026 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 KKK13059.1 - 0.0069 16.4 0.2 0.41 10.7 0.0 2.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain 2-Hacid_dh_C PF02826.14 KKK13059.1 - 0.011 14.8 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 KKK13059.1 - 0.027 13.3 1.8 1.4 7.6 0.2 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KKK13059.1 - 0.11 12.5 5.3 1.2 9.2 0.3 2.9 1 1 3 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK13059.1 - 0.11 11.5 1.1 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family F420_oxidored PF03807.12 KKK13059.1 - 0.18 12.2 1.6 5 7.6 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_oxidored PF12831.2 KKK13059.1 - 0.2 10.6 12.6 0.049 12.6 1.2 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK13059.1 - 0.44 9.5 4.4 0.098 11.6 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 KKK13059.1 - 0.84 8.1 5.1 1.3 7.5 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KKK13059.1 - 9.9 5.9 7.3 23 4.7 0.1 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding AhpC-TSA PF00578.16 KKK13063.1 - 4.2e-32 110.4 0.0 5.7e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KKK13063.1 - 1.1e-13 50.5 0.1 1.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KKK13063.1 - 4.9e-12 45.6 0.0 6.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin AMP-binding PF00501.23 KKK13064.1 - 5.4e-79 265.5 0.1 7.5e-79 265.0 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KKK13064.1 - 1e-40 139.4 0.0 1.6e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 KKK13064.1 - 1.6e-29 102.5 0.0 1.5e-27 96.1 0.0 2.7 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KKK13064.1 - 2.6e-14 53.2 0.1 5.3e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KKK13064.1 - 8e-11 42.1 0.1 2.8e-10 40.3 0.1 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain NAD_binding_10 PF13460.1 KKK13064.1 - 0.00041 20.4 0.0 0.073 13.0 0.0 2.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KKK13064.1 - 0.0011 18.4 0.0 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK13064.1 - 0.042 12.5 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FliP PF00813.15 KKK13065.1 - 0.44 10.2 4.3 1.1 8.8 1.0 2.2 2 0 0 2 2 2 0 FliP family ABC2_membrane PF01061.19 KKK13065.1 - 1.2 8.2 8.4 0.14 11.2 0.5 2.3 3 0 0 3 3 3 0 ABC-2 type transporter CCSMST1 PF15013.1 KKK13065.1 - 2.8 7.8 4.4 1.1 9.2 0.6 2.0 1 1 1 2 2 2 0 CCSMST1 family Hydantoinase_B PF02538.9 KKK13066.1 - 4.5e-191 635.6 0.0 5.6e-191 635.3 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KKK13066.1 - 2.1e-92 309.3 0.1 3.4e-91 305.3 0.0 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KKK13066.1 - 5.6e-54 182.2 0.0 2.1e-51 173.9 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region APH PF01636.18 KKK13067.1 - 6.8e-06 25.9 1.4 0.0012 18.6 0.4 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KKK13067.1 - 2.2e-05 23.6 0.1 4.6e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KKK13067.1 - 0.016 14.8 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase U79_P34 PF03064.11 KKK13067.1 - 0.052 13.0 5.8 0.094 12.2 4.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3523 PF12037.3 KKK13067.1 - 0.078 11.9 11.2 0.14 11.0 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) HECT PF00632.20 KKK13068.1 - 9.8e-85 284.4 0.0 1.5e-84 283.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Glyco_hydro_71 PF03659.9 KKK13070.1 - 9.9e-154 511.4 6.5 9.9e-154 511.4 4.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 FAD_binding_9 PF08021.6 KKK13070.1 - 0.13 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain MAT_Alpha1 PF04769.7 KKK13071.1 - 3.6e-30 104.8 0.0 5.8e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Hexapep PF00132.19 KKK13072.1 - 9.3e-11 40.7 16.7 0.0032 16.8 0.4 4.5 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK13072.1 - 1.2e-05 24.7 6.5 0.0023 17.4 0.6 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase gerPA PF10676.4 KKK13072.1 - 0.62 9.9 3.1 2.5 8.0 0.4 2.3 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF Pkinase PF00069.20 KKK13073.1 - 5.2e-55 186.4 0.0 8e-38 130.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13073.1 - 5e-26 91.3 0.0 1.5e-24 86.4 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13073.1 - 5.8e-06 25.4 0.0 2e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KKK13073.1 - 1.8e-05 24.5 3.2 3.8e-05 23.5 0.1 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family SEP PF08059.8 KKK13075.1 - 8.6e-29 99.6 0.1 1.7e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KKK13075.1 - 1.3e-15 57.2 0.0 2.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KKK13075.1 - 6.1e-13 48.0 1.8 1e-12 47.3 1.3 1.4 1 0 0 1 1 1 1 UBA-like domain ParA PF10609.4 KKK13076.1 - 1.9e-28 98.1 4.9 1.9e-28 98.1 3.4 2.7 2 1 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KKK13076.1 - 1.5e-11 44.0 0.0 3.8e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KKK13076.1 - 5.6e-08 32.1 0.0 1.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 KKK13076.1 - 2.4e-05 24.3 0.1 0.00015 21.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KKK13076.1 - 0.00054 19.1 1.3 0.0011 18.1 0.9 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 KKK13076.1 - 0.00055 19.4 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 KKK13076.1 - 0.0048 16.2 0.2 0.02 14.2 0.1 1.9 2 0 0 2 2 2 1 YhjQ protein ArgK PF03308.11 KKK13076.1 - 0.005 15.6 0.3 0.0085 14.8 0.2 1.3 1 0 0 1 1 1 1 ArgK protein AAA_26 PF13500.1 KKK13076.1 - 0.059 12.9 0.5 0.46 10.0 0.2 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KKK13076.1 - 0.062 12.9 0.1 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 KKK13076.1 - 0.079 12.1 0.8 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SRP54 PF00448.17 KKK13076.1 - 0.087 12.2 0.3 1.6 8.1 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain COG2 PF06148.6 KKK13077.1 - 1.2e-36 125.5 3.6 1.2e-36 125.5 2.5 1.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KKK13077.1 - 6.6e-06 25.8 2.5 5.5e-05 22.9 1.7 2.5 1 1 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 KKK13077.1 - 9.6e-06 25.5 1.5 9.6e-06 25.5 1.0 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 KKK13077.1 - 0.0011 17.8 0.4 0.0019 17.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Bul1_C PF04426.7 KKK13077.1 - 0.044 12.9 0.3 0.09 11.9 0.1 1.5 1 1 0 1 1 1 0 Bul1 C terminus Sec34 PF04136.10 KKK13077.1 - 0.067 12.8 2.3 0.18 11.5 0.3 2.2 1 1 1 2 2 2 0 Sec34-like family FlaC_arch PF05377.6 KKK13077.1 - 0.18 11.7 8.0 4.4 7.2 0.3 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 KKK13077.1 - 0.25 10.4 2.1 0.24 10.5 0.2 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KKK13077.1 - 0.69 8.5 9.3 0.062 11.9 2.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1090 PF06476.7 KKK13077.1 - 1.5 8.4 6.3 3.4 7.3 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1090) NPV_P10 PF05531.7 KKK13077.1 - 1.7 8.9 5.0 4.4 7.6 0.6 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 KKK13077.1 - 1.9 6.2 4.0 1.3 6.7 1.9 1.2 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 KKK13077.1 - 2.9 7.4 7.7 2.1 7.8 1.5 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 KKK13077.1 - 3.8 7.0 17.7 0.26 10.8 7.8 2.2 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 KKK13077.1 - 7.2 5.5 8.3 0.61 9.0 2.3 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 RasGEF PF00617.14 KKK13078.1 - 8.5e-56 188.6 0.5 2.2e-55 187.2 0.1 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KKK13078.1 - 8.6e-19 67.5 0.0 2.9e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 KKK13078.1 - 1.8e-06 27.4 0.0 5.3e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK13078.1 - 1.2e-05 24.6 0.0 3.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 SH3 domain Med16 PF11635.3 KKK13083.1 - 1.7e-185 618.1 0.0 3.7e-102 342.6 0.0 2.2 1 1 1 2 2 2 2 Mediator complex subunit 16 Ribosomal_L29 PF00831.18 KKK13084.1 - 1.7e-19 69.2 0.3 1.7e-19 69.2 0.2 1.7 2 0 0 2 2 2 1 Ribosomal L29 protein IncA PF04156.9 KKK13084.1 - 0.025 14.1 1.7 0.032 13.8 1.2 1.2 1 0 0 1 1 1 0 IncA protein DUF3585 PF12130.3 KKK13084.1 - 0.23 11.3 5.6 0.35 10.7 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) Cortex-I_coil PF09304.5 KKK13084.1 - 0.32 11.0 7.7 0.056 13.4 1.8 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil FliT PF05400.8 KKK13084.1 - 1.4 9.3 5.2 15 6.0 0.2 2.4 2 0 0 2 2 2 0 Flagellar protein FliT V-SNARE_C PF12352.3 KKK13085.1 - 1.4e-13 50.7 0.1 1.4e-13 50.7 0.0 3.0 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Surfac_D-trimer PF09006.6 KKK13085.1 - 0.012 15.3 1.4 0.38 10.5 0.2 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation GOLGA2L5 PF15070.1 KKK13085.1 - 0.023 13.2 5.5 0.03 12.8 3.8 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Dor1 PF04124.7 KKK13085.1 - 0.68 8.3 7.1 1.4 7.3 4.9 1.5 1 1 0 1 1 1 0 Dor1-like family SATase_N PF06426.9 KKK13085.1 - 0.7 10.1 3.4 1.4 9.2 0.7 2.3 2 1 0 2 2 2 0 Serine acetyltransferase, N-terminal CBFD_NFYB_HMF PF00808.18 KKK13086.1 - 2.8e-05 24.0 0.0 5.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pilt PF15453.1 KKK13086.1 - 0.13 11.9 10.7 0.17 11.5 7.4 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Spore_coat_CotO PF14153.1 KKK13086.1 - 0.19 11.1 14.9 0.28 10.6 10.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO TATR PF03430.8 KKK13086.1 - 0.21 10.2 5.5 0.26 9.8 3.6 1.3 1 1 0 1 1 1 0 Trans-activating transcriptional regulator CDC27 PF09507.5 KKK13086.1 - 2.6 7.1 24.4 3.4 6.7 16.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 KKK13086.1 - 6.5 5.1 38.9 8.6 4.7 27.0 1.1 1 0 0 1 1 1 0 Daxx Family SIR2 PF02146.12 KKK13087.1 - 3.3e-24 85.5 0.2 3.2e-23 82.3 0.0 2.5 2 1 0 2 2 2 1 Sir2 family Zn-ribbon_8 PF09723.5 KKK13087.1 - 0.089 12.7 2.3 0.37 10.7 1.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain VASP_tetra PF08776.6 KKK13088.1 - 0.15 11.4 1.0 0.35 10.2 0.7 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain Glyco_hydro_7 PF00840.15 KKK13091.1 - 3e-210 698.0 20.3 3.4e-210 697.8 14.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Abhydrolase_6 PF12697.2 KKK13092.1 - 1.4e-21 77.4 0.5 7.3e-21 75.0 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK13092.1 - 3.2e-14 52.8 0.0 6.8e-12 45.3 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK13092.1 - 4.1e-12 46.1 0.0 7.6e-11 41.9 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KKK13092.1 - 3.6e-07 29.6 0.0 0.097 11.9 0.0 3.2 3 0 0 3 3 3 3 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KKK13092.1 - 1.5e-05 24.7 0.0 5.1e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase FSH1 PF03959.8 KKK13092.1 - 0.0028 17.1 0.1 1.1 8.7 0.0 2.8 3 0 0 3 3 3 1 Serine hydrolase (FSH1) DUF2048 PF09752.4 KKK13092.1 - 0.0056 15.6 0.4 0.03 13.1 0.5 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2048) BAAT_C PF08840.6 KKK13092.1 - 0.027 14.1 0.1 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 KKK13092.1 - 0.054 13.0 0.0 0.58 9.6 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KKK13092.1 - 0.11 12.1 0.2 0.41 10.2 0.1 1.9 2 0 0 2 2 2 0 Lipase (class 3) WD40 PF00400.27 KKK13093.1 - 0.00036 20.3 1.3 0.21 11.5 0.0 4.2 4 1 0 4 4 4 1 WD domain, G-beta repeat Nucleoplasmin PF03066.10 KKK13093.1 - 0.036 13.5 2.9 0.072 12.6 2.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin TFIIF_alpha PF05793.7 KKK13093.1 - 1 7.6 13.2 1.8 6.8 9.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TLP-20 PF06088.6 KKK13093.1 - 1.4 8.6 4.6 0.29 10.7 0.9 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nop14 PF04147.7 KKK13093.1 - 1.8 6.3 8.9 2.6 5.8 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KKK13093.1 - 8.4 4.2 10.8 13 3.6 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein FAD_binding_4 PF01565.18 KKK13100.1 - 0.022 14.2 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain eIF2A PF08662.6 KKK13101.1 - 1.6e-83 279.1 0.0 1e-82 276.5 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KKK13101.1 - 0.00099 18.9 0.7 7.1 6.6 0.1 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat CDV3 PF15359.1 KKK13101.1 - 0.006 16.6 0.7 0.006 16.6 0.5 3.6 2 1 1 3 3 3 1 Carnitine deficiency-associated protein 3 DPPIV_N PF00930.16 KKK13101.1 - 0.039 12.5 0.0 2.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Glyco_transf_8 PF01501.15 KKK13102.1 - 6.4e-12 45.3 0.0 7.3e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 ELO PF01151.13 KKK13115.1 - 9e-63 211.8 20.9 1.1e-62 211.6 14.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SAC3_GANP PF03399.11 KKK13117.1 - 1.5e-67 227.1 0.1 1.9e-67 226.7 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KKK13117.1 - 0.00011 21.9 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 R3H-assoc PF13902.1 KKK13118.1 - 8e-25 87.3 5.8 2.1e-24 85.9 4.1 1.8 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 KKK13118.1 - 0.0031 17.1 0.6 0.0063 16.1 0.1 1.9 2 0 0 2 2 2 1 R3H domain Peptidase_M28 PF04389.12 KKK13119.1 - 7.3e-27 94.2 0.6 1.2e-26 93.5 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KKK13119.1 - 1.9e-06 27.5 0.1 4e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Inositol_P PF00459.20 KKK13120.1 - 4.6e-39 134.3 0.1 8.1e-39 133.5 0.1 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Chitin_synth_1 PF01644.12 KKK13121.1 - 1.8e-86 288.0 0.2 2.9e-86 287.2 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KKK13121.1 - 7.9e-34 115.2 0.2 1.7e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KKK13121.1 - 1.5e-20 73.1 0.4 6e-19 67.8 0.0 2.4 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KKK13121.1 - 1.8e-08 34.3 0.7 8.1e-08 32.1 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK13121.1 - 2.2e-06 27.6 0.0 5.3e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Hpt PF01627.18 KKK13123.1 - 2.8e-11 43.2 0.0 5.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Hpt domain Pkinase PF00069.20 KKK13124.1 - 1.1e-10 41.0 0.0 2.2e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13124.1 - 5.3e-08 32.2 0.0 2.3e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13124.1 - 0.00097 18.1 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like tRNA-synt_1b PF00579.20 KKK13125.1 - 5.6e-56 189.8 0.0 7e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RTC4 PF14474.1 KKK13125.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 RTC4-like domain HCMVantigenic_N PF12154.3 KKK13126.1 - 2.5 8.0 8.2 0.19 11.6 2.0 1.9 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV Ribonuc_L-PSP PF01042.16 KKK13127.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Endoribonuclease L-PSP DUF1794 PF08768.6 KKK13127.1 - 0.075 12.8 0.1 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1794) Glyco_hydro_72 PF03198.9 KKK13128.1 - 1.1e-101 339.9 0.1 1.4e-101 339.6 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 KKK13128.1 - 0.00014 20.9 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 KKK13128.1 - 0.0032 16.7 0.1 0.037 13.2 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 KKK13128.1 - 0.13 11.5 0.0 0.62 9.3 0.0 2.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Alpha-amylase PF00128.19 KKK13129.1 - 9.3e-103 343.9 0.2 1.7e-102 343.0 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KKK13129.1 - 0.036 12.9 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Mo-nitro_C PF06967.6 KKK13130.1 - 0.077 13.1 0.1 0.84 9.8 0.1 2.3 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Sds3 PF08598.6 KKK13131.1 - 1.1e-50 172.1 6.0 2.5e-49 167.6 4.1 2.2 1 1 0 1 1 1 1 Sds3-like Lectin_N PF03954.9 KKK13131.1 - 0.081 12.3 0.6 0.91 8.9 0.1 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Fungal_trans PF04082.13 KKK13132.1 - 5.1e-10 38.6 0.1 9e-10 37.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13132.1 - 7.3e-07 28.9 10.8 2e-06 27.6 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.9 KKK13133.1 - 1.3e-34 119.6 0.2 1.7e-34 119.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DOCK-C2 PF14429.1 KKK13141.1 - 3.8e-33 114.6 0.0 7.2e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KKK13141.1 - 5.8e-15 55.0 0.1 1.5e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KKK13141.1 - 5.9e-06 25.5 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK13141.1 - 0.0003 20.3 0.1 0.0023 17.4 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KKK13141.1 - 0.19 11.2 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain CD47 PF04549.9 KKK13141.1 - 0.79 9.7 0.1 1.5 8.7 0.1 1.4 1 0 0 1 1 1 0 CD47 transmembrane region SRP40_C PF05022.7 KKK13142.1 - 2e-23 82.6 0.5 5.6e-23 81.2 0.3 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF2653 PF10850.3 KKK13142.1 - 0.19 12.0 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) Sec3_C PF09763.4 KKK13143.1 - 5.1e-219 728.9 0.3 6.8e-219 728.5 0.2 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KKK13143.1 - 5.6e-30 103.0 0.1 1.2e-29 102.0 0.1 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 KKK13143.1 - 0.026 14.6 0.3 0.088 12.9 0.2 1.9 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Vps52 PF04129.7 KKK13143.1 - 0.029 12.9 0.3 0.057 11.9 0.2 1.4 1 0 0 1 1 1 0 Vps52 / Sac2 family F-box-like PF12937.2 KKK13144.1 - 0.00026 20.6 0.1 0.00069 19.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK13144.1 - 0.00057 19.4 0.1 0.0019 17.8 0.0 1.9 2 0 0 2 2 2 1 F-box domain p450 PF00067.17 KKK13145.1 - 6.3e-39 133.7 0.0 1.1e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_18 PF00704.23 KKK13146.1 - 2.6e-19 69.8 0.8 9.6e-19 68.0 0.1 1.7 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 SSP160 PF06933.6 KKK13146.1 - 4.3 5.1 20.4 7.1 4.4 14.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Abhydrolase_3 PF07859.8 KKK13147.1 - 2.8e-66 223.1 0.1 3.7e-66 222.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK13147.1 - 4.3e-08 32.3 0.0 7.7e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KKK13147.1 - 2.5e-07 30.1 0.0 4.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 KKK13147.1 - 0.0048 15.5 0.0 0.015 13.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) PhzC-PhzF PF02567.11 KKK13147.1 - 0.038 13.2 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein FTR1 PF03239.9 KKK13148.1 - 2.2e-91 306.0 1.5 2.2e-91 306.0 1.1 1.6 2 0 0 2 2 2 1 Iron permease FTR1 family Cu-oxidase_2 PF07731.9 KKK13149.1 - 2.4e-41 140.4 9.2 1e-38 131.9 0.5 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KKK13149.1 - 2.1e-40 137.1 11.2 3.1e-39 133.3 1.1 3.7 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK13149.1 - 3.5e-37 127.7 6.2 1.2e-35 122.8 0.4 3.5 3 1 0 3 3 3 1 Multicopper oxidase PhoD PF09423.5 KKK13150.1 - 5.2e-60 203.2 0.0 7.4e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_18 PF00704.23 KKK13150.1 - 8e-06 25.5 0.0 1.8e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 ATG16 PF08614.6 KKK13151.1 - 0.0001 22.2 19.7 0.0001 22.2 13.6 4.7 1 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 KKK13151.1 - 0.0047 17.0 12.0 0.0047 17.0 8.3 6.0 3 2 2 6 6 6 3 Fibrinogen alpha/beta chain family Cep57_CLD_2 PF14197.1 KKK13151.1 - 0.032 14.1 0.3 0.032 14.1 0.2 7.9 7 2 3 10 10 10 0 Centrosome localisation domain of PPC89 SRF-TF PF00319.13 KKK13152.1 - 1.4e-23 81.8 0.2 2e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 KKK13152.1 - 0.014 13.5 0.2 0.019 13.0 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Mg_trans_NIPA PF05653.9 KKK13153.1 - 1.4e-16 60.3 11.1 5.3e-09 35.4 1.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 KKK13153.1 - 0.00024 21.1 6.6 0.00024 21.1 4.6 3.0 3 1 0 3 3 3 1 EamA-like transporter family Neurensin PF14927.1 KKK13153.1 - 0.2 11.0 4.5 2.7 7.3 0.6 3.0 2 1 0 2 2 2 0 Neurensin Multi_Drug_Res PF00893.14 KKK13153.1 - 0.89 10.0 13.5 2.8 8.4 1.4 3.1 2 2 1 3 3 3 0 Small Multidrug Resistance protein DUF3353 PF11833.3 KKK13153.1 - 7.8 5.9 8.3 2.4 7.5 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) vATP-synt_E PF01991.13 KKK13154.1 - 2.2e-59 200.0 12.2 2.6e-59 199.8 8.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.1 KKK13154.1 - 0.51 10.5 3.2 36 4.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) E1-E2_ATPase PF00122.15 KKK13156.1 - 3.5e-12 45.8 0.0 3.5e-12 45.8 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 KKK13156.1 - 5e-12 46.3 0.1 9.8e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK13156.1 - 2.9e-11 44.2 0.5 5.4e-10 40.0 0.3 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK13156.1 - 3.3e-11 42.9 0.0 9e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK13156.1 - 0.046 13.2 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Robl_LC7 PF03259.12 KKK13158.1 - 9.3e-06 25.1 0.2 0.0059 16.1 0.0 3.0 3 0 0 3 3 3 2 Roadblock/LC7 domain DUF605 PF04652.11 KKK13158.1 - 4 6.7 18.7 4.7 6.5 13.0 1.2 1 0 0 1 1 1 0 Vta1 like SEN1_N PF12726.2 KKK13159.1 - 7.1e-232 771.5 8.5 9e-232 771.1 5.9 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KKK13159.1 - 1.1e-67 228.0 0.5 1.1e-67 228.0 0.4 2.6 4 0 0 4 4 4 1 AAA domain AAA_12 PF13087.1 KKK13159.1 - 1.8e-62 210.2 0.0 4.9e-62 208.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK13159.1 - 1e-10 41.1 0.4 3.4e-10 39.5 0.3 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KKK13159.1 - 1.3e-08 34.6 0.2 1.3e-05 24.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 KKK13159.1 - 1e-06 28.3 1.0 6.8e-06 25.5 0.1 2.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KKK13159.1 - 3.9e-06 26.5 0.2 0.069 12.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KKK13159.1 - 0.00011 21.7 0.4 0.0019 17.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-CCHC PF00098.18 KKK13159.1 - 0.0013 18.5 11.0 0.0057 16.5 1.4 2.7 2 0 0 2 2 2 2 Zinc knuckle AAA_25 PF13481.1 KKK13159.1 - 0.0072 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KKK13159.1 - 0.014 15.2 0.0 0.072 12.9 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 KKK13159.1 - 0.067 13.4 0.2 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-CCHC_3 PF13917.1 KKK13159.1 - 0.19 11.5 19.2 1.1 9.0 1.2 4.1 1 1 2 3 3 3 0 Zinc knuckle AAA_23 PF13476.1 KKK13159.1 - 0.28 11.4 0.0 0.28 11.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain Glyco_hydro_71 PF03659.9 KKK13160.1 - 4.3e-143 476.4 9.6 5e-143 476.2 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KKK13160.1 - 0.032 13.9 0.4 0.087 12.5 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Neural_ProG_Cyt PF06567.6 KKK13161.1 - 0.047 13.8 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain TUG-UBL1 PF11470.3 KKK13163.1 - 4.6e-25 87.3 0.1 1.3e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 KKK13163.1 - 0.00036 20.5 0.3 0.0024 17.9 0.0 2.3 2 0 0 2 2 2 1 UBX domain RBD PF02196.10 KKK13163.1 - 0.06 13.1 0.1 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain DUF605 PF04652.11 KKK13163.1 - 9.7 5.4 21.7 0.87 8.9 11.0 1.8 2 0 0 2 2 2 0 Vta1 like Proteasome PF00227.21 KKK13164.1 - 4.8e-38 130.3 0.0 5.3e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ank PF00023.25 KKK13165.1 - 5.1e-22 76.5 0.0 6e-07 28.9 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KKK13165.1 - 6.9e-21 74.3 0.0 2.5e-20 72.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KKK13165.1 - 9.6e-15 53.2 0.0 0.00024 21.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KKK13165.1 - 1.7e-13 50.3 0.0 3.6e-05 23.8 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK13165.1 - 1.5e-12 47.6 0.1 4.4e-06 27.0 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) AAA_22 PF13401.1 KKK13165.1 - 2.7e-05 24.3 0.0 0.0023 18.0 0.0 2.7 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK13165.1 - 4.7e-05 23.4 0.8 0.00045 20.2 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 KKK13165.1 - 0.0021 17.7 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 KKK13165.1 - 0.0048 16.3 0.0 0.024 14.0 0.0 2.1 2 1 0 2 2 2 1 AAA-like domain Glyco_hydro_71 PF03659.9 KKK13166.1 - 7.2e-135 449.3 8.3 8.4e-135 449.1 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ufd2P_core PF10408.4 KKK13167.1 - 4e-203 676.1 8.9 4.9e-203 675.8 6.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KKK13167.1 - 4.8e-27 93.7 3.6 4.9e-27 93.6 0.7 2.5 2 0 0 2 2 2 1 U-box domain Focal_AT PF03623.8 KKK13167.1 - 0.092 12.2 0.2 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 Focal adhesion targeting region Steroid_dh PF02544.11 KKK13168.1 - 2.2e-15 56.7 1.0 1.5e-10 41.0 0.8 3.4 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KKK13168.1 - 0.0011 18.3 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) HATPase_c PF02518.21 KKK13169.1 - 8.3e-20 70.5 0.0 1.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK13169.1 - 1.7e-15 56.9 0.3 0.00038 20.4 0.0 3.6 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.20 KKK13169.1 - 5.3e-07 29.5 0.1 2.3e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 KKK13169.1 - 0.0081 15.8 0.0 0.025 14.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EHN PF06441.7 KKK13170.1 - 9.6e-35 118.8 4.0 1.8e-34 118.0 0.1 2.4 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KKK13170.1 - 6.7e-17 62.1 1.5 9.8e-17 61.5 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK13170.1 - 1e-12 48.1 0.0 2.7e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2416 PF10315.4 KKK13171.1 - 2.8e-06 27.5 0.1 3.9e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DUF1977 PF09320.6 KKK13172.1 - 7.3e-29 100.1 0.0 1.2e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KKK13172.1 - 1.3e-23 82.4 0.1 2.6e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DMAP1 PF05499.7 KKK13173.1 - 0.00057 19.4 7.0 0.0015 18.1 1.9 2.6 2 1 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.1 KKK13173.1 - 0.06 13.4 0.2 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain EMP24_GP25L PF01105.19 KKK13174.1 - 1.9e-50 171.1 0.1 2.2e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Meth_synt_2 PF01717.13 KKK13175.1 - 4.2e-144 479.4 0.0 5.2e-140 466.0 0.0 2.5 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KKK13175.1 - 2.9e-123 411.1 0.0 1.5e-109 366.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 KKK13175.1 - 0.18 11.3 1.2 0.34 10.4 0.1 2.1 2 0 0 2 2 2 0 Short C-terminal domain BBP1_C PF15272.1 KKK13176.1 - 0.1 12.1 0.2 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal PCI PF01399.22 KKK13182.1 - 1.8e-12 47.4 0.0 3.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain RNase_P_Rpp14 PF01900.14 KKK13182.1 - 0.013 15.4 0.1 0.1 12.5 0.1 2.2 2 1 0 2 2 2 0 Rpp14/Pop5 family ATG22 PF11700.3 KKK13182.1 - 0.018 13.5 0.2 0.023 13.2 0.1 1.3 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like STAS_2 PF13466.1 KKK13182.1 - 3 7.9 9.8 2.1 8.4 0.1 3.3 3 1 1 4 4 4 0 STAS domain Arylsulfotran_2 PF14269.1 KKK13183.1 - 3e-48 164.5 0.2 4.3e-48 163.9 0.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) ADK PF00406.17 KKK13183.1 - 1.7e-34 118.8 0.0 5.1e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 Adenylate kinase Arylsulfotrans PF05935.6 KKK13183.1 - 2.8e-12 45.9 0.4 4.4e-11 41.9 0.3 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) AAA_18 PF13238.1 KKK13183.1 - 0.0012 19.1 0.0 0.0027 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KKK13183.1 - 0.011 15.1 0.0 0.94 8.8 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Ribosomal_60s PF00428.14 KKK13183.1 - 0.016 15.5 9.2 0.016 15.5 6.4 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hexokinase_2 PF03727.11 KKK13184.1 - 2.7e-36 125.0 0.0 4.1e-28 98.2 0.0 2.2 1 1 1 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KKK13184.1 - 5.6e-36 123.8 0.0 8.2e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF840 PF05801.6 KKK13184.1 - 0.14 12.3 0.0 6.8 6.8 0.0 2.7 3 0 0 3 3 3 0 Lagovirus protein of unknown function (DUF840) RhoGAP PF00620.22 KKK13185.1 - 2.3e-48 163.6 0.0 9.9e-48 161.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KKK13185.1 - 1.1e-13 51.2 1.6 2.5e-13 50.0 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain MBA1 PF07961.6 KKK13186.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.4 1 1 0 1 1 1 0 MBA1-like protein Fungal_trans PF04082.13 KKK13187.1 - 4.7e-22 78.1 0.0 9e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13187.1 - 3.3e-06 26.9 9.5 5.7e-06 26.1 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.4 KKK13187.1 - 0.09 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein adh_short_C2 PF13561.1 KKK13188.1 - 2e-28 99.7 0.1 3.5e-28 98.9 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK13188.1 - 8.7e-24 84.3 1.2 1.4e-23 83.5 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Fungal_trans PF04082.13 KKK13188.1 - 3.2e-23 81.9 2.0 5.3e-23 81.2 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.5 KKK13188.1 - 3.9e-08 33.1 0.1 1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 KR domain DUF3694 PF12473.3 KKK13188.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinesin protein EOS1 PF12326.3 KKK13189.1 - 5.1e-30 104.0 15.3 1.3e-25 89.7 5.9 2.2 1 1 1 2 2 2 2 N-glycosylation protein Pol_alpha_B_N PF08418.5 KKK13189.1 - 0.27 10.7 2.1 0.38 10.2 1.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal UPF0139 PF03669.8 KKK13190.1 - 0.0019 17.7 0.3 0.0023 17.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) SUI1 PF01253.17 KKK13191.1 - 1.4e-29 101.6 6.0 1.9e-29 101.3 4.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 KKK13191.1 - 0.11 12.6 0.6 0.33 11.0 0.1 1.8 1 1 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) RRM_1 PF00076.17 KKK13192.1 - 0.00021 20.8 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK13192.1 - 0.00023 20.9 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13192.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Med12 PF09497.5 KKK13193.1 - 3.4e-27 94.1 0.7 1.1e-26 92.6 0.5 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 FH2 PF02181.18 KKK13194.1 - 6.5e-89 298.3 3.2 8e-89 298.0 2.3 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain DHBP_synthase PF00926.14 KKK13198.1 - 1e-70 236.9 0.0 6.6e-70 234.2 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase APS_kinase PF01583.15 KKK13201.1 - 4.3e-70 234.4 0.0 5.2e-70 234.1 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KKK13201.1 - 7.4e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK13201.1 - 6.9e-05 23.6 0.0 0.00012 22.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK13201.1 - 8.1e-05 22.9 0.0 0.00015 22.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK13201.1 - 0.0011 18.9 0.1 0.0022 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 KKK13201.1 - 0.0013 17.9 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KKK13201.1 - 0.069 12.6 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KKK13201.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Pyr_redox_3 PF13738.1 KKK13242.1 - 1.8e-22 80.3 0.0 2.9e-21 76.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK13242.1 - 3.2e-16 58.6 0.1 3.3e-13 48.6 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KKK13242.1 - 1.3e-11 44.8 0.0 6.7e-10 39.1 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK13242.1 - 5.2e-11 42.0 0.1 3e-07 29.6 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK13242.1 - 8e-07 29.0 0.0 7.4e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK13242.1 - 6.5e-05 23.2 0.1 0.54 10.6 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK13242.1 - 0.0002 20.4 0.2 0.0011 17.9 0.1 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KKK13242.1 - 0.0005 19.0 2.8 0.016 14.1 0.0 3.4 4 1 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK13242.1 - 0.0017 17.5 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 KKK13242.1 - 0.0023 16.8 0.0 0.0042 16.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KKK13242.1 - 0.0023 17.7 0.1 2.1 8.1 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KKK13242.1 - 0.0037 16.9 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KKK13242.1 - 0.0051 15.7 0.3 0.23 10.2 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KKK13242.1 - 0.0099 14.3 0.2 0.045 12.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KKK13242.1 - 0.012 14.7 0.0 0.077 12.0 0.0 2.2 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.14 KKK13242.1 - 0.026 13.6 0.0 0.064 12.4 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 KKK13242.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain MutS_V PF00488.16 KKK13254.1 - 1.2e-80 270.2 0.0 2e-80 269.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KKK13254.1 - 1.1e-52 178.8 0.0 2e-52 177.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KKK13254.1 - 4.3e-33 113.7 0.0 1.5e-32 111.9 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KKK13254.1 - 1.7e-14 54.0 0.0 6.8e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KKK13254.1 - 1.8e-12 47.2 0.2 4e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KKK13254.1 - 0.044 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KKK13254.1 - 0.15 12.0 0.2 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain tRNA-synt_2 PF00152.15 KKK13255.1 - 2.6e-105 351.9 0.0 3.6e-105 351.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KKK13255.1 - 0.00075 19.1 0.1 0.002 17.7 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-codon PF01336.20 KKK13255.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_1b PF00579.20 KKK13256.1 - 4.9e-73 245.8 0.0 7e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Med8 PF10232.4 KKK13257.1 - 1.6e-51 174.9 1.0 1.9e-51 174.7 0.7 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 CENP-B_dimeris PF09026.5 KKK13257.1 - 0.00063 19.9 5.6 0.0012 19.0 3.9 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Myc_N PF01056.13 KKK13257.1 - 0.00073 18.8 1.9 0.00073 18.8 1.3 2.1 2 0 0 2 2 2 1 Myc amino-terminal region Nucleoplasmin PF03066.10 KKK13257.1 - 0.056 12.9 8.1 0.09 12.2 5.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 KKK13257.1 - 8.2 5.0 13.1 0.18 10.4 4.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) UbiA PF01040.13 KKK13258.1 - 4.2e-31 108.0 19.9 6.3e-31 107.5 13.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family PQ-loop PF04193.9 KKK13259.1 - 1.9e-19 68.9 4.6 4.6e-10 38.9 0.9 2.7 2 0 0 2 2 2 2 PQ loop repeat CbtB PF09489.5 KKK13259.1 - 0.73 9.7 4.7 1.8 8.5 0.1 2.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Fungal_trans_2 PF11951.3 KKK13260.1 - 1.2e-07 30.7 4.9 2.2e-07 29.8 0.2 2.3 2 1 1 3 3 3 2 Fungal specific transcription factor domain DUF3602 PF12223.3 KKK13261.1 - 2.4e-05 24.6 1.8 2.4e-05 24.6 1.2 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) DUF1479 PF07350.7 KKK13262.1 - 8.5e-169 561.4 0.0 9.8e-169 561.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) CRAL_TRIO PF00650.15 KKK13263.1 - 1.1e-25 89.9 0.0 3.5e-25 88.3 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain DUF3235 PF11574.3 KKK13263.1 - 0.46 10.7 6.0 1.3 9.3 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) DUF1620 PF07774.8 KKK13264.1 - 3e-73 245.6 0.0 6.8e-73 244.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KKK13264.1 - 2e-22 79.8 14.8 2.7e-19 69.5 1.9 3.2 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 KKK13264.1 - 2.4e-08 33.1 5.2 0.2 11.2 0.0 6.0 6 0 0 6 6 6 3 PQQ enzyme repeat PQQ_3 PF13570.1 KKK13264.1 - 0.015 15.5 4.5 0.25 11.6 0.0 4.4 4 1 0 4 4 4 0 PQQ-like domain Aa_trans PF01490.13 KKK13265.1 - 1.8e-95 319.8 14.8 3e-95 319.1 10.3 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short PF00106.20 KKK13265.1 - 6.4e-16 58.7 0.2 5.7e-15 55.6 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK13265.1 - 6.6e-08 32.6 0.0 1.9e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Trp_Tyr_perm PF03222.8 KKK13265.1 - 9.2e-05 21.4 17.2 9.2e-05 21.4 11.9 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family KR PF08659.5 KKK13265.1 - 0.00012 21.8 0.0 0.002 17.8 0.0 2.2 2 0 0 2 2 2 1 KR domain Rad51 PF08423.6 KKK13267.1 - 4.4e-125 415.7 0.0 6e-125 415.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 KKK13267.1 - 8e-11 41.5 0.0 1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KKK13267.1 - 2.3e-10 40.4 1.7 2.4e-09 37.2 0.2 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain AAA_25 PF13481.1 KKK13267.1 - 7.3e-10 38.5 0.0 1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KKK13267.1 - 7.7e-08 31.7 0.0 1.7e-07 30.5 0.0 1.6 2 1 0 2 2 2 1 KaiC RNA_pol_A_CTD PF03118.10 KKK13267.1 - 0.071 12.5 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain UDPGP PF01704.13 KKK13268.1 - 2.2e-55 187.8 0.0 3.2e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KKK13268.1 - 0.0028 17.7 0.0 0.0095 16.0 0.0 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain zf-CCHC PF00098.18 KKK13269.1 - 1.9e-44 147.5 54.6 2.3e-07 30.3 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KKK13269.1 - 3e-09 36.4 39.1 0.006 16.2 0.1 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 KKK13269.1 - 3.1e-08 33.1 39.7 0.067 12.8 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 KKK13269.1 - 0.068 12.6 0.2 0.068 12.6 0.2 7.2 3 2 4 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.1 KKK13269.1 - 7.9 6.2 44.5 0.23 11.1 1.0 6.9 6 1 1 7 7 7 0 Zinc knuckle Pro_isomerase PF00160.16 KKK13271.1 - 8.7e-34 116.9 0.0 1.4e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KKK13271.1 - 4.3e-16 58.2 0.1 1e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13271.1 - 6.4e-12 45.2 0.0 1.5e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK13271.1 - 1.6e-09 37.4 0.1 3.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK13271.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Methyltransf_16 PF10294.4 KKK13272.1 - 5.3e-06 25.9 0.0 0.00039 19.9 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Ribosomal_S24e PF01282.14 KKK13273.1 - 9.7e-35 118.2 0.1 1.6e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e SPACA7 PF15307.1 KKK13274.1 - 0.0014 18.6 1.3 2.5 8.2 0.1 3.2 2 0 0 2 2 2 2 Sperm acrosome-associated protein 7 DivIVA PF05103.8 KKK13274.1 - 0.0018 18.3 27.2 0.031 14.3 7.0 3.5 3 1 1 4 4 4 3 DivIVA protein IncA PF04156.9 KKK13274.1 - 7.2 6.1 32.1 7.8 6.0 9.5 3.3 1 1 2 3 3 3 0 IncA protein CLTH PF10607.4 KKK13275.1 - 4.4e-36 123.7 0.0 7.4e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KKK13275.1 - 7.2e-16 58.4 0.3 1.4e-15 57.4 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KKK13275.1 - 0.0002 20.9 0.7 0.0005 19.7 0.1 2.0 2 0 0 2 2 2 1 LisH OpuAC PF04069.7 KKK13275.1 - 0.028 13.7 0.6 1.3 8.2 0.2 2.3 1 1 1 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system MFS_1 PF07690.11 KKK13292.1 - 6.9e-31 107.2 56.2 4.1e-29 101.4 12.9 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK13292.1 - 7.8e-17 60.6 14.4 1.8e-16 59.5 10.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1206 PF06724.6 KKK13292.1 - 0.001 18.7 1.5 0.0064 16.2 0.1 3.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1206) Pec_lyase_C PF00544.14 KKK13293.1 - 2.5e-16 59.7 1.5 4.9e-16 58.7 1.1 1.5 1 0 0 1 1 1 1 Pectate lyase GST_C PF00043.20 KKK13294.1 - 7.7e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK13294.1 - 2.7e-10 39.9 0.8 3.4e-10 39.6 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK13294.1 - 5.5e-10 39.2 0.0 9.8e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KKK13294.1 - 2.5e-07 30.8 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KKK13294.1 - 1.7e-06 28.3 0.1 2.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KKK13294.1 - 2e-06 27.6 0.0 4.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PapG_N PF03627.8 KKK13295.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 PapG carbohydrate binding domain FAD_binding_4 PF01565.18 KKK13296.1 - 2.1e-32 111.4 7.7 4.5e-32 110.4 5.1 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KKK13296.1 - 1.1e-06 28.4 0.1 2.5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 KKK13297.1 - 1.2e-31 109.0 6.9 2.1e-31 108.2 4.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK13297.1 - 1.5e-09 37.6 0.0 3.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like VWA_2 PF13519.1 KKK13298.1 - 3.4e-05 24.0 0.0 9.9e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain IBR PF01485.16 KKK13298.1 - 0.00012 21.8 7.5 0.00012 21.8 5.2 5.0 5 2 1 6 6 6 1 IBR domain VWA PF00092.23 KKK13298.1 - 0.00097 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain WLM PF08325.5 KKK13300.1 - 6.6e-37 127.1 0.2 7.8e-37 126.9 0.1 1.0 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 KKK13300.1 - 6e-06 26.1 0.4 8.9e-06 25.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 KKK13300.1 - 8.7e-05 22.2 0.3 0.0001 22.0 0.2 1.2 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 KKK13300.1 - 0.013 15.5 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase MA superfamily DUF955 PF06114.8 KKK13300.1 - 0.019 14.7 0.1 0.062 13.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF955) Mito_carr PF00153.22 KKK13301.1 - 9.4e-40 134.2 0.1 4.5e-25 87.1 0.0 2.7 2 1 1 3 3 3 2 Mitochondrial carrier protein EF-hand_6 PF13405.1 KKK13301.1 - 2.1e-19 67.6 2.3 7.9e-07 28.4 0.1 5.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 KKK13301.1 - 1.4e-18 66.8 4.3 1e-08 35.1 0.5 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KKK13301.1 - 2.4e-18 63.9 2.8 3.5e-07 29.0 0.0 5.4 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.1 KKK13301.1 - 1e-15 57.0 5.8 0.00092 18.7 0.1 5.4 4 2 2 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.1 KKK13301.1 - 1.2e-13 49.7 0.8 1.9e-05 23.7 0.1 4.7 5 0 0 5 5 5 3 EF hand EF-hand_9 PF14658.1 KKK13301.1 - 0.00093 19.0 0.1 2.5 8.0 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain Prenylcys_lyase PF07156.9 KKK13302.1 - 5.8e-39 134.0 0.0 2.9e-28 98.8 0.0 2.4 1 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 KKK13302.1 - 2.6e-12 46.5 0.0 6.4e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KKK13302.1 - 8.4e-08 31.7 0.0 5.9e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KKK13302.1 - 4.2e-06 26.6 0.1 7.8e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KKK13302.1 - 1.8e-05 23.8 0.4 7.1e-05 21.8 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK13302.1 - 0.0024 18.2 0.1 2.8 8.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK13302.1 - 0.0029 17.7 0.0 0.043 13.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK13302.1 - 0.003 17.4 0.3 0.18 11.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK13302.1 - 0.0047 15.4 0.3 0.94 7.8 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 KKK13302.1 - 0.039 13.0 0.1 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 KKK13302.1 - 0.055 12.3 0.0 7.9 5.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KKK13302.1 - 0.11 11.5 0.1 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK13302.1 - 0.16 10.7 0.6 0.77 8.5 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain PDCD2_C PF04194.8 KKK13303.1 - 6.8e-53 178.6 0.0 1.3e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain SHMT PF00464.14 KKK13304.1 - 1.4e-207 688.8 0.0 1.6e-207 688.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KKK13304.1 - 9.4e-06 24.8 0.0 2.7e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KKK13304.1 - 0.00013 20.7 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KKK13304.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase AcetylCoA_hydro PF02550.10 KKK13305.1 - 1.2e-52 178.5 0.0 1.8e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KKK13305.1 - 6.9e-25 87.5 0.0 1.4e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF2076 PF09849.4 KKK13311.1 - 6.7e-06 26.3 0.9 6.7e-06 26.3 0.6 2.7 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF1183 PF06682.7 KKK13311.1 - 0.0062 16.1 0.9 0.0062 16.1 0.6 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1183) ETRAMP PF09716.5 KKK13311.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4366 PF14283.1 KKK13311.1 - 0.16 11.3 1.1 0.24 10.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Zip PF02535.17 KKK13311.1 - 3 6.7 7.1 0.15 11.0 0.7 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Na_Ca_ex PF01699.19 KKK13312.1 - 3.9e-38 130.2 32.0 4.7e-20 71.6 8.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein UbiD PF01977.11 KKK13313.1 - 9.4e-109 363.5 0.1 1.1e-108 363.3 0.1 1.1 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF3756 PF12581.3 KKK13313.1 - 0.075 12.7 0.1 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) UbiD PF01977.11 KKK13314.1 - 4.6e-13 48.3 0.0 5.2e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Anoctamin PF04547.7 KKK13315.1 - 3.9e-105 352.1 3.8 4.8e-105 351.8 2.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Flavoprotein PF02441.14 KKK13316.1 - 1.2e-30 105.8 0.2 1.5e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein NAD_binding_1 PF00175.16 KKK13317.1 - 1.7e-10 41.4 0.0 3.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KKK13317.1 - 1.1e-08 35.1 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KKK13317.1 - 1.7e-08 34.7 0.1 5.9e-08 33.0 0.0 2.0 3 0 0 3 3 3 1 Globin Protoglobin PF11563.3 KKK13317.1 - 0.00097 18.8 0.0 0.0025 17.4 0.0 1.7 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 KKK13317.1 - 0.045 13.6 0.0 0.3 10.9 0.0 2.2 2 1 1 3 3 3 0 Ferric reductase NAD binding domain MIP PF00230.15 KKK13318.1 - 1.7e-44 151.9 8.7 2.2e-44 151.6 6.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein CD24 PF14984.1 KKK13318.1 - 0.0087 15.8 0.0 6 6.7 0.0 2.7 2 0 0 2 2 2 2 CD24 protein AA_permease_2 PF13520.1 KKK13319.1 - 1.6e-63 214.7 50.3 2.1e-63 214.3 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK13319.1 - 1.7e-11 43.1 43.1 8.8e-11 40.8 30.3 1.7 1 1 0 1 1 1 1 Amino acid permease Herpes_US9 PF06072.6 KKK13319.1 - 0.54 10.1 4.3 4.7 7.1 0.0 3.8 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Pneumo_phosprot PF02478.11 KKK13320.1 - 0.52 9.7 7.4 0.71 9.3 5.1 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Macoilin PF09726.4 KKK13320.1 - 2.4 6.3 11.7 2.7 6.1 8.1 1.0 1 0 0 1 1 1 0 Transmembrane protein zf-rbx1 PF12678.2 KKK13347.1 - 1.4e-11 44.3 2.1 3.2e-11 43.1 1.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KKK13347.1 - 1.2e-10 41.0 7.0 4.6e-10 39.1 4.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK13347.1 - 5.4e-07 29.1 4.5 9.1e-06 25.2 1.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK13347.1 - 7.8e-07 28.6 3.2 1.6e-06 27.6 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK13347.1 - 6.3e-06 25.8 1.6 1.5e-05 24.6 1.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KKK13347.1 - 1.3e-05 25.0 2.1 1.3e-05 25.0 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KKK13347.1 - 1.9e-05 24.2 3.9 3.9e-05 23.2 2.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KKK13347.1 - 0.0078 16.0 4.3 0.038 13.8 3.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KKK13347.1 - 0.02 14.7 1.3 0.05 13.4 0.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CopD PF05425.8 KKK13347.1 - 1.6 8.9 10.0 0.43 10.8 3.8 2.1 1 1 1 2 2 2 0 Copper resistance protein D zf-RING_4 PF14570.1 KKK13347.1 - 1.9 8.1 4.8 0.61 9.7 1.2 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3431 PF11913.3 KKK13348.1 - 2.7e-90 301.7 0.0 3.4e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) MFS_1 PF07690.11 KKK13349.1 - 2e-21 76.1 18.7 2e-21 76.1 13.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK13349.1 - 1.4e-11 43.4 4.0 5.8e-06 24.9 0.8 3.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KKK13349.1 - 0.00026 20.7 4.9 0.18 11.6 0.1 4.0 4 0 0 4 4 4 2 MFS_1 like family Kelch_3 PF13415.1 KKK13350.1 - 7.9e-38 127.7 14.3 1.3e-08 34.7 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KKK13350.1 - 2.8e-33 113.4 11.2 2.8e-08 33.3 0.9 6.9 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK13350.1 - 2.6e-31 107.0 3.9 6.1e-08 32.4 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KKK13350.1 - 4.9e-30 102.8 0.1 7.7e-11 41.3 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KKK13350.1 - 2.3e-26 90.8 9.5 1.5e-10 40.8 0.5 6.5 3 2 3 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KKK13350.1 - 6.4e-21 73.2 6.9 1.6e-08 33.9 0.3 6.5 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 KKK13350.1 - 0.0082 14.9 0.1 0.15 10.7 0.0 2.9 3 1 1 4 4 4 1 Recombination activating protein 2 Syntaxin-6_N PF09177.6 KKK13350.1 - 0.0082 16.5 7.3 0.0082 16.5 5.0 6.7 3 2 3 6 6 6 1 Syntaxin 6, N-terminal Ribosomal_L44 PF00935.14 KKK13351.1 - 0.56 10.2 4.8 0.46 10.5 0.6 2.4 1 1 1 2 2 2 0 Ribosomal protein L44 Raptor_N PF14538.1 KKK13352.1 - 1.3e-64 216.7 0.0 2.4e-64 215.8 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KKK13352.1 - 2.3e-07 30.4 7.2 0.28 11.1 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat Peptidase_C14 PF00656.17 KKK13352.1 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain BBS2_Mid PF14783.1 KKK13352.1 - 0.0028 17.3 1.7 0.6 9.9 0.1 2.9 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 KKK13352.1 - 0.026 14.2 0.1 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 KKK13352.1 - 0.11 12.6 0.1 28 5.1 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat DUF3439 PF11921.3 KKK13353.1 - 0.03 14.0 3.0 1.3 8.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) zf-RING_2 PF13639.1 KKK13354.1 - 4.4e-14 52.0 5.8 7.1e-14 51.3 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KKK13354.1 - 3.8e-11 42.5 0.0 8.5e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 KKK13354.1 - 2e-09 37.3 5.2 3.3e-09 36.6 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK13354.1 - 3.9e-09 36.4 1.8 7.2e-09 35.6 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KKK13354.1 - 1.2e-08 34.5 3.6 1.8e-08 33.8 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK13354.1 - 3.2e-08 33.1 3.2 4.8e-08 32.5 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK13354.1 - 1.1e-07 31.3 2.8 1.8e-07 30.7 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KKK13354.1 - 0.00046 19.9 0.7 0.0009 19.0 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KKK13354.1 - 0.014 15.1 2.9 0.035 13.8 2.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 KKK13354.1 - 0.038 13.9 2.5 0.1 12.5 1.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KKK13354.1 - 0.053 13.5 4.2 0.096 12.7 2.9 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 KKK13354.1 - 0.065 13.1 3.4 0.19 11.6 2.4 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KKK13354.1 - 0.36 10.4 3.0 0.62 9.6 2.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KKK13354.1 - 0.65 9.7 3.0 1.2 8.9 2.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KKK13354.1 - 2.2 8.3 3.8 4.1 7.4 2.7 1.5 1 0 0 1 1 1 0 RING-like domain Arrestin_C PF02752.17 KKK13355.1 - 1.2e-22 80.4 0.0 1.1e-21 77.4 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KKK13355.1 - 3.6e-05 23.6 0.6 0.14 11.9 0.0 2.6 1 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain EF-hand_9 PF14658.1 KKK13356.1 - 0.002 18.0 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KKK13356.1 - 0.0081 16.2 0.0 0.049 13.7 0.0 2.3 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 KKK13356.1 - 0.037 13.6 0.0 7.2 6.3 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair UCH PF00443.24 KKK13357.1 - 1.8e-36 125.6 0.0 8.7e-36 123.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK13357.1 - 6.1e-11 42.2 0.0 1.4e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PUL PF08324.6 KKK13358.1 - 6.4e-42 143.1 0.0 8.6e-42 142.7 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KKK13358.1 - 3.3e-41 140.5 0.0 5.3e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KKK13358.1 - 3.7e-16 58.6 0.0 7e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KKK13358.1 - 0.00093 19.3 0.1 0.0048 17.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KKK13358.1 - 0.0027 17.4 0.1 0.0065 16.2 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 KKK13358.1 - 0.0069 15.9 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.16 KKK13358.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family DUF2847 PF11009.3 KKK13358.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Redoxin PF08534.5 KKK13358.1 - 0.038 13.5 0.1 0.086 12.3 0.1 1.5 1 0 0 1 1 1 0 Redoxin Alb1 PF09135.6 KKK13359.1 - 4.1e-29 101.4 16.2 6.1e-29 100.8 11.2 1.3 1 0 0 1 1 1 1 Alb1 DUF4201 PF13870.1 KKK13359.1 - 0.0013 18.1 1.8 0.0018 17.7 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) ABC_tran_2 PF12848.2 KKK13359.1 - 1.1 9.1 5.6 2.4 8.0 3.9 1.7 1 0 0 1 1 1 0 ABC transporter L31 PF09784.4 KKK13359.1 - 3.3 7.8 8.3 11 6.0 2.1 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 Vps16_C PF04840.7 KKK13360.1 - 1.2e-80 270.8 0.0 3.2e-80 269.4 0.0 1.6 2 0 0 2 2 2 1 Vps16, C-terminal region Vps16_N PF04841.8 KKK13360.1 - 2.8e-70 236.9 0.0 6.4e-70 235.7 0.0 1.6 1 1 0 1 1 1 1 Vps16, N-terminal region Pkinase PF00069.20 KKK13362.1 - 1.5e-69 234.0 0.1 2.8e-69 233.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13362.1 - 2.4e-52 177.5 0.1 4.3e-52 176.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KKK13362.1 - 4.2e-23 81.5 0.1 1.1e-21 76.9 0.0 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 KKK13362.1 - 2.5e-20 72.8 0.1 4.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KKK13362.1 - 1.6e-09 37.9 0.0 3.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KKK13362.1 - 4.3e-07 29.1 0.0 8.6e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK13362.1 - 0.013 15.2 0.2 0.013 15.2 0.1 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK13362.1 - 0.017 13.9 0.1 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NAD_kinase PF01513.16 KKK13363.1 - 1.7e-45 155.0 0.0 5.6e-45 153.3 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 KKK13364.1 - 6.5e-26 90.3 0.0 9.5e-26 89.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TPR_11 PF13414.1 KKK13365.1 - 8.5e-29 99.0 27.6 1.8e-06 27.5 0.1 10.5 9 2 2 11 11 11 8 TPR repeat TPR_2 PF07719.12 KKK13365.1 - 3.3e-28 95.2 29.0 0.00044 19.9 0.0 12.0 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.23 KKK13365.1 - 9.8e-27 91.4 17.6 7.3e-05 22.2 0.0 10.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 KKK13365.1 - 6.3e-23 78.7 22.1 0.00015 21.3 0.0 11.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 KKK13365.1 - 1.5e-20 71.8 28.9 0.0059 17.1 0.1 12.1 11 1 1 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 KKK13365.1 - 3e-19 69.1 18.5 0.00084 19.6 0.0 8.3 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 KKK13365.1 - 2e-17 62.8 31.6 2.4e-05 24.2 1.2 10.3 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 KKK13365.1 - 4e-13 49.6 34.3 0.0015 19.1 0.0 11.2 10 2 3 13 13 13 5 Tetratricopeptide repeat TPR_17 PF13431.1 KKK13365.1 - 2.7e-10 39.6 8.8 0.45 10.8 0.0 9.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK13365.1 - 8.3e-10 38.4 26.2 0.35 11.4 0.1 12.0 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 KKK13365.1 - 5.9e-06 25.6 32.3 0.00038 20.0 0.3 10.3 12 0 0 12 12 12 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK13365.1 - 1.1e-05 25.4 16.3 0.036 14.1 0.3 7.4 8 0 0 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 BAR PF03114.13 KKK13366.1 - 4.4e-63 212.8 4.0 5.5e-63 212.5 2.8 1.1 1 0 0 1 1 1 1 BAR domain Brix PF04427.13 KKK13367.1 - 9.2e-28 97.2 0.1 7.1e-27 94.2 0.0 2.0 2 0 0 2 2 2 1 Brix domain Nop14 PF04147.7 KKK13367.1 - 0.14 10.0 20.0 0.19 9.6 13.9 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 KKK13367.1 - 0.16 9.7 6.5 0.22 9.3 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 KKK13367.1 - 0.16 9.9 14.0 0.23 9.4 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 KKK13367.1 - 1.7 8.2 20.1 3.6 7.2 14.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 KKK13367.1 - 9 5.4 9.5 13 4.9 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein tRNA-synt_2b PF00587.20 KKK13368.1 - 5.4e-57 192.1 0.1 8.9e-57 191.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KKK13368.1 - 2e-19 69.2 0.0 1e-18 67.0 0.0 2.3 1 0 0 1 1 1 1 Anticodon binding domain Sybindin PF04099.7 KKK13369.1 - 6.8e-26 90.6 0.0 8.9e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KKK13369.1 - 0.001 18.9 0.1 0.0017 18.2 0.1 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 KKK13370.1 - 1.6e-63 214.3 0.0 3.9e-63 213.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13370.1 - 1.7e-26 92.8 0.0 2.4e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13370.1 - 0.0037 16.2 0.0 0.0076 15.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK13370.1 - 0.0039 16.2 0.0 0.0074 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK13370.1 - 0.077 12.7 0.3 1.5 8.5 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pept_tRNA_hydro PF01195.14 KKK13371.1 - 6.7e-20 71.3 0.0 2.1e-05 24.1 0.0 3.4 2 1 1 3 3 3 3 Peptidyl-tRNA hydrolase SET PF00856.23 KKK13372.1 - 2.6e-21 76.6 0.3 2.6e-21 76.6 0.2 4.6 5 1 0 5 5 5 1 SET domain SRI PF08236.6 KKK13372.1 - 4.7e-21 74.5 13.7 1e-20 73.4 9.5 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 KKK13372.1 - 0.0087 15.9 1.4 0.022 14.5 1.0 1.8 1 0 0 1 1 1 1 WW domain COPI_C PF06957.6 KKK13372.1 - 0.043 12.3 5.3 0.085 11.3 3.7 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF3287 PF11690.3 KKK13372.1 - 1.8 8.6 8.5 0.45 10.6 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) eIF-6 PF01912.13 KKK13373.1 - 6.1e-78 260.4 0.3 7.7e-78 260.1 0.2 1.0 1 0 0 1 1 1 1 eIF-6 family Pkinase PF00069.20 KKK13374.1 - 1.2e-56 191.7 0.0 1.9e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13374.1 - 1.9e-33 115.6 0.0 7.6e-32 110.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13374.1 - 2.2e-08 33.4 0.0 6.8e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KKK13374.1 - 0.0055 16.4 0.1 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family AT_hook PF02178.14 KKK13375.1 - 0.027 14.0 1.5 0.027 14.0 1.0 2.7 2 0 0 2 2 2 0 AT hook motif Peptidase_M24 PF00557.19 KKK13376.1 - 1.1e-42 145.9 0.1 3.2e-40 137.9 0.0 2.2 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KKK13376.1 - 3.1e-25 88.1 0.0 5.8e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain KapB PF08810.5 KKK13376.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase associated protein B Sec63 PF02889.11 KKK13377.1 - 8.7e-48 163.1 0.0 3.2e-46 158.0 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KKK13377.1 - 9.1e-18 63.7 0.7 2.1e-17 62.5 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 KKK13377.1 - 0.048 12.8 0.1 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) TT_ORF2 PF02957.10 KKK13377.1 - 9.9 6.8 8.6 3.3 8.4 3.1 2.0 2 0 0 2 2 2 0 TT viral ORF2 DUF3157 PF11355.3 KKK13378.1 - 0.039 13.2 0.0 0.064 12.5 0.0 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3157) Ribonucleas_3_3 PF14622.1 KKK13380.1 - 2.5e-28 98.5 0.0 5e-28 97.6 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KKK13380.1 - 1.3e-06 28.7 0.0 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Sdh_cyt PF01127.17 KKK13381.1 - 5.1e-25 87.6 3.0 5.1e-25 87.6 2.0 1.7 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Transaldolase PF00923.14 KKK13382.1 - 7.5e-50 169.6 0.0 9e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Cation_efflux PF01545.16 KKK13383.1 - 1.2e-63 214.8 0.5 1.6e-63 214.4 0.4 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 KKK13383.1 - 0.068 11.7 0.2 0.15 10.6 0.1 1.5 1 1 0 1 1 1 0 Cation transport protein DUF808 PF05661.7 KKK13383.1 - 0.36 9.6 3.5 3.8 6.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF808) Citrate_synt PF00285.16 KKK13385.1 - 1.5e-101 339.6 0.0 1.8e-101 339.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase RRM_1 PF00076.17 KKK13386.1 - 1.2e-05 24.8 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK13386.1 - 3.5e-05 23.5 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13386.1 - 0.001 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KKK13386.1 - 0.0081 16.3 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PAP1 PF08601.5 KKK13386.1 - 5.7 6.5 10.4 9.6 5.7 7.2 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Mito_carr PF00153.22 KKK13387.1 - 1.3e-27 95.3 6.1 2.4e-12 46.4 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein MMS19_N PF14500.1 KKK13388.1 - 7.1e-95 317.2 0.1 2e-94 315.7 0.1 1.8 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KKK13388.1 - 2.6e-69 233.9 5.9 3.1e-68 230.3 0.1 3.1 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal DUF1454 PF07305.7 KKK13388.1 - 0.018 14.1 1.0 1 8.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1454) Fasciclin PF02469.17 KKK13389.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain DUF106 PF01956.11 KKK13390.1 - 2.1e-53 180.2 1.3 2.6e-53 180.0 0.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 KKK13391.1 - 1.2e-50 171.2 0.1 1.5e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MFS_2 PF13347.1 KKK13391.1 - 0.03 12.7 0.3 0.041 12.2 0.2 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein THF_DHG_CYH PF00763.18 KKK13392.1 - 2.6e-17 62.9 0.0 3.9e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KKK13392.1 - 1.5e-12 46.8 0.0 1.4e-09 37.2 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TPP_enzyme_N PF02776.13 KKK13393.1 - 9.7e-47 158.6 0.2 4.7e-45 153.1 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KKK13393.1 - 1.1e-35 122.3 0.1 2.5e-35 121.2 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KKK13393.1 - 2.6e-17 62.7 0.1 6.1e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 KKK13393.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TPR_11 PF13414.1 KKK13394.1 - 5e-27 93.3 5.2 2e-11 43.3 0.2 4.4 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 KKK13394.1 - 7.7e-24 82.2 2.8 2.5e-08 33.1 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KKK13394.1 - 2.7e-23 79.9 2.3 1.6e-07 30.6 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KKK13394.1 - 1.2e-17 62.7 3.7 8.4e-05 22.8 0.0 5.9 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK13394.1 - 9.4e-16 58.0 7.8 2.5e-06 27.9 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KKK13394.1 - 2.1e-15 55.5 4.6 0.0012 18.8 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KKK13394.1 - 8.1e-13 48.5 2.0 0.0006 20.1 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK13394.1 - 9.7e-13 47.8 7.6 5.1e-09 35.9 0.2 4.0 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KKK13394.1 - 7.6e-12 44.0 1.7 0.0011 18.6 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 KKK13394.1 - 2.7e-10 40.2 4.2 0.0043 17.1 0.0 4.9 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK13394.1 - 4.6e-10 38.5 0.3 0.0004 19.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KKK13394.1 - 9.2e-07 28.6 3.0 0.0038 17.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK13394.1 - 1.7e-06 28.0 1.8 4.7e-05 23.4 0.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KKK13394.1 - 5.8e-06 26.4 2.2 0.92 10.1 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 KKK13394.1 - 0.00045 19.9 0.0 0.096 12.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 KKK13394.1 - 0.0015 17.6 0.3 0.58 9.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 KKK13394.1 - 0.0094 15.8 0.9 0.73 9.7 0.2 3.6 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 KKK13394.1 - 0.018 14.9 1.0 0.49 10.3 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NatB_MDM20 PF09797.4 KKK13394.1 - 0.037 12.7 0.0 0.072 11.7 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TOM20_plant PF06552.7 KKK13394.1 - 0.045 13.3 0.1 2.1 7.9 0.0 3.1 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4192 PF13830.1 KKK13394.1 - 0.33 10.5 7.3 1 8.9 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4192) RRM_1 PF00076.17 KKK13395.1 - 1.2e-31 108.0 0.0 2.2e-18 65.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13395.1 - 4.2e-24 84.3 0.1 8.3e-12 44.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 KKK13395.1 - 1.2e-16 60.3 0.7 3.5e-16 58.8 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain RRM_5 PF13893.1 KKK13395.1 - 1.6e-13 50.3 0.0 1.8e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 KKK13395.1 - 2.8e-06 27.1 11.7 4.8e-06 26.3 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 KKK13395.1 - 0.047 13.2 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Piwi PF02171.12 KKK13396.1 - 2.8e-69 233.3 0.0 4.5e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KKK13396.1 - 2.4e-12 46.0 0.0 1.5e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KKK13396.1 - 2e-09 36.8 0.0 5.9e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 PAZ domain SHS2_Rpb7-N PF03876.12 KKK13398.1 - 1.3e-14 54.0 0.0 2.4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KKK13398.1 - 8.9e-09 35.3 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 KKK13399.1 - 1.2e-24 86.0 0.1 2.5e-24 84.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF3852 PF12963.2 KKK13399.1 - 0.2 11.7 0.3 0.2 11.7 0.2 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3852) ATP-synt_ab PF00006.20 KKK13400.1 - 6.9e-71 238.1 0.0 1.1e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KKK13400.1 - 1.1e-26 93.4 0.3 3.3e-26 91.9 0.1 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KKK13400.1 - 2.6e-15 56.3 3.1 6.4e-15 55.1 2.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KKK13400.1 - 0.0047 16.7 0.9 0.016 15.1 0.6 1.9 1 0 0 1 1 1 1 HAS barrel domain Fungal_trans PF04082.13 KKK13401.1 - 0.00023 20.1 0.4 0.00063 18.6 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13401.1 - 0.00023 20.9 6.3 0.00058 19.7 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M24 PF00557.19 KKK13402.1 - 1.6e-17 63.7 0.0 1.8e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 SH2_2 PF14633.1 KKK13403.1 - 8.7e-81 270.1 0.0 2.9e-80 268.5 0.0 1.9 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 KKK13403.1 - 1.7e-37 127.9 4.9 1.7e-37 127.9 3.4 2.8 2 0 0 2 2 2 1 Death-like domain of SPT6 YqgF PF14639.1 KKK13403.1 - 7.2e-31 106.7 0.1 3.2e-30 104.6 0.0 2.2 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 KKK13403.1 - 8.1e-31 106.2 0.1 1.6e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 KKK13403.1 - 1.8e-21 76.1 29.4 1.8e-21 76.1 20.4 5.0 4 2 1 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KKK13403.1 - 9.4e-18 64.3 9.8 1.5e-17 63.7 3.5 3.3 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 KKK13403.1 - 2.4e-05 24.0 0.0 6.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 KKK13403.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2716 PF10898.3 KKK13403.1 - 0.032 14.2 0.2 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) B12-binding PF02310.14 KKK13403.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Pkinase PF00069.20 KKK13404.1 - 3.4e-61 206.6 0.0 4.3e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13404.1 - 1.9e-36 125.4 0.0 2.6e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13404.1 - 1.3e-05 24.3 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KKK13404.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KKK13404.1 - 0.052 13.2 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KKK13404.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PfkB PF00294.19 KKK13411.1 - 7.2e-68 228.9 0.1 8.3e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KKK13411.1 - 0.0017 17.5 0.0 0.0035 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF1770 PF08589.5 KKK13412.1 - 3.1e-21 75.8 0.4 9e-21 74.3 0.2 1.7 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1770) EST1_DNA_bind PF10373.4 KKK13414.1 - 2.1e-65 220.7 0.1 3.4e-65 220.0 0.1 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KKK13414.1 - 8.7e-23 80.7 0.1 1.8e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 KKK13414.1 - 0.00019 20.9 0.3 0.00045 19.8 0.2 1.5 1 0 0 1 1 1 1 TPR repeat Ada_Zn_binding PF02805.11 KKK13415.1 - 2.1e-29 100.8 5.3 3.6e-29 100.1 3.7 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KKK13415.1 - 4.4e-07 29.5 0.0 9.5e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KKK13415.1 - 0.002 18.2 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain BAR PF03114.13 KKK13416.1 - 3.9e-48 163.9 8.0 5.2e-48 163.5 5.5 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KKK13416.1 - 1.5e-07 30.6 3.6 1.9e-07 30.3 2.5 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PMEI PF04043.10 KKK13416.1 - 0.01 15.7 0.7 1.7 8.5 0.1 2.4 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Apo-CIII PF05778.7 KKK13416.1 - 0.013 14.9 0.1 0.033 13.5 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Stirrup PF09061.1 KKK13416.1 - 0.1 12.4 0.1 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Stirrup DUF1925 PF09094.6 KKK13416.1 - 0.22 11.5 0.7 2.7 8.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) APG6 PF04111.7 KKK13416.1 - 0.89 8.5 7.6 1.5 7.7 5.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 WHIM1 PF15612.1 KKK13417.1 - 0.00032 20.5 0.0 0.00072 19.3 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 KKK13417.1 - 0.016 15.1 0.5 0.043 13.7 0.3 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Ribosomal_L2_C PF03947.13 KKK13418.1 - 4.9e-27 94.2 6.7 1.6e-23 82.8 2.8 2.4 1 1 1 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KKK13418.1 - 2.7e-14 52.9 0.1 5.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SNF2_N PF00176.18 KKK13419.1 - 4.8e-84 281.6 1.0 4.8e-84 281.6 0.7 2.7 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KKK13419.1 - 3.1e-25 87.8 2.6 3.7e-24 84.4 0.1 3.1 3 0 0 3 3 3 1 Bromodomain SnAC PF14619.1 KKK13419.1 - 4.1e-19 68.5 4.1 4.1e-19 68.5 2.9 3.6 3 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 KKK13419.1 - 1.7e-17 63.0 0.1 4.2e-16 58.5 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.8 KKK13419.1 - 2.5e-16 59.2 15.8 2.5e-16 59.2 11.0 2.6 2 0 0 2 2 2 1 HSA QLQ PF08880.6 KKK13419.1 - 1.1e-13 50.3 1.5 1.1e-13 50.3 1.1 2.3 2 0 0 2 2 2 1 QLQ M11L PF11099.3 KKK13419.1 - 0.078 12.7 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Apoptosis regulator M11L like Pkinase PF00069.20 KKK13421.1 - 1.3e-67 227.7 0.0 2.8e-66 223.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13421.1 - 1.3e-49 168.6 0.0 7.9e-48 162.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KKK13421.1 - 6.7e-32 109.5 0.0 1.3e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 KKK13421.1 - 3.4e-14 52.7 0.1 8.8e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KKK13421.1 - 6.8e-12 45.0 0.1 1.7e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 KKK13421.1 - 2.4e-08 33.3 0.0 7.8e-05 21.7 0.0 2.7 3 0 0 3 3 3 2 Kinase-like RA PF00788.18 KKK13421.1 - 6.2e-07 29.8 0.0 1.2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 KKK13421.1 - 0.021 13.9 0.0 0.046 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2019 PF09450.5 KKK13421.1 - 0.067 13.0 0.3 0.18 11.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Seadorna_VP7 PF07387.6 KKK13421.1 - 0.15 10.8 0.0 0.32 9.7 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 SNF2_N PF00176.18 KKK13422.1 - 5.6e-43 146.8 0.1 8.2e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 KKK13422.1 - 1.1e-05 24.9 5.4 2.1e-05 24.0 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK13422.1 - 2.1e-05 24.4 8.4 6e-05 22.9 5.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK13422.1 - 0.00021 20.9 7.6 0.00049 19.7 5.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK13422.1 - 0.021 14.4 10.0 0.052 13.2 7.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK13422.1 - 0.029 14.1 7.2 0.076 12.8 5.0 1.8 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 KKK13422.1 - 0.039 13.4 2.0 0.11 12.0 1.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SNF2_N PF00176.18 KKK13494.1 - 8.2e-32 110.1 0.0 5.9e-29 100.8 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK13494.1 - 0.00055 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MOSC_N PF03476.11 KKK13496.1 - 1.1e-29 102.5 0.0 2e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KKK13496.1 - 1.8e-24 85.6 0.0 3.6e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 KKK13496.1 - 9e-22 77.3 0.0 1.5e-21 76.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_M1 PF01433.15 KKK13497.1 - 3.4e-129 431.3 7.3 7.5e-65 219.5 0.3 2.1 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 KKK13497.1 - 9.4e-95 317.5 0.4 6.7e-94 314.7 0.1 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KKK13497.1 - 1.5e-19 70.3 0.1 2.8e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 KKK13497.1 - 0.0065 16.1 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) DUF3543 PF12063.3 KKK13498.1 - 1.3e-98 328.9 0.0 2e-98 328.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KKK13498.1 - 1.1e-63 214.7 0.0 1.7e-63 214.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13498.1 - 2.4e-44 151.3 0.0 3.5e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13498.1 - 0.017 14.0 0.0 0.037 13.0 0.0 1.5 1 1 0 1 1 1 0 Kinase-like CTP_transf_1 PF01148.15 KKK13499.1 - 3.5e-05 23.6 9.5 0.00045 19.9 2.1 3.0 4 0 0 4 4 4 2 Cytidylyltransferase family Med9 PF07544.8 KKK13499.1 - 0.25 11.1 0.4 0.58 9.9 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 HAT PF02184.11 KKK13500.1 - 0.06 13.0 0.0 4.5 7.1 0.2 2.6 2 1 0 2 2 2 0 HAT (Half-A-TPR) repeat FAM70 PF14967.1 KKK13501.1 - 3.9 6.5 6.8 5.2 6.1 4.7 1.1 1 0 0 1 1 1 0 FAM70 protein Herpes_capsid PF06112.6 KKK13501.1 - 7.7 6.5 11.2 11 5.9 7.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ribonuc_L-PSP PF01042.16 KKK13502.1 - 3.7e-17 62.1 0.0 2e-07 30.7 0.0 3.3 3 0 0 3 3 3 3 Endoribonuclease L-PSP ABC2_membrane PF01061.19 KKK13517.1 - 7.6e-75 250.6 46.0 8.5e-45 152.5 11.8 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KKK13517.1 - 6.6e-38 130.1 2.6 4.6e-20 72.3 0.0 3.2 4 0 0 4 4 2 2 ABC transporter PDR_CDR PF06422.7 KKK13517.1 - 2.8e-27 94.3 1.4 6.9e-27 93.1 0.0 2.3 2 0 0 2 2 1 1 CDR ABC transporter ABC_trans_N PF14510.1 KKK13517.1 - 5.5e-08 32.7 0.1 1.6e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 KKK13517.1 - 4.2e-06 26.3 0.1 0.0012 18.3 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KKK13517.1 - 8.6e-06 25.9 0.4 0.017 15.2 0.0 3.6 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.1 KKK13517.1 - 1.2e-05 24.8 0.0 0.24 10.7 0.1 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KKK13517.1 - 2.2e-05 24.3 0.8 0.0086 15.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KKK13517.1 - 2.3e-05 24.4 0.2 0.0034 17.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KKK13517.1 - 3.4e-05 23.0 0.0 0.0017 17.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KKK13517.1 - 5.4e-05 23.9 0.0 0.026 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KKK13517.1 - 6.5e-05 22.3 0.3 0.23 10.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KKK13517.1 - 8.1e-05 22.7 1.9 0.53 10.2 0.0 3.8 3 1 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 KKK13517.1 - 9.6e-05 21.9 0.0 0.49 9.8 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KKK13517.1 - 0.00019 21.3 0.0 0.25 11.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 KKK13517.1 - 0.00024 21.0 0.0 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KKK13517.1 - 0.00024 21.3 0.0 0.0099 16.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KKK13517.1 - 0.00044 19.8 0.5 0.065 12.8 0.2 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KKK13517.1 - 0.0016 18.1 0.5 0.22 11.1 0.3 2.6 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 KKK13517.1 - 0.0025 17.0 0.3 0.071 12.3 0.0 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_24 PF13479.1 KKK13517.1 - 0.0069 15.9 0.1 0.39 10.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KKK13517.1 - 0.0088 15.5 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain NB-ARC PF00931.17 KKK13517.1 - 0.014 14.2 0.1 4.1 6.1 0.2 2.9 3 0 0 3 3 3 0 NB-ARC domain Miro PF08477.8 KKK13517.1 - 0.016 15.6 0.0 1.2 9.6 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 KKK13517.1 - 0.018 14.8 0.3 1.3 8.8 0.0 3.3 3 0 0 3 3 3 0 Dynamin family AAA PF00004.24 KKK13517.1 - 0.041 14.0 0.0 15 5.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 KKK13517.1 - 0.05 12.6 0.2 0.27 10.2 0.1 2.0 2 0 0 2 2 2 0 Septin AAA_30 PF13604.1 KKK13517.1 - 0.053 13.1 1.2 2 7.9 0.4 2.4 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KKK13517.1 - 0.077 11.8 0.0 2.7 6.8 0.0 2.4 3 0 0 3 3 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 KKK13517.1 - 0.11 11.5 0.9 1.1 8.2 0.3 2.3 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.4 KKK13517.1 - 0.14 11.6 0.2 0.48 9.9 0.2 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 KKK13517.1 - 0.15 11.0 0.0 9.6 5.1 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 KKK13517.1 - 0.19 11.4 4.4 9.8 6.0 0.0 3.0 3 0 0 3 3 3 0 Part of AAA domain Epimerase PF01370.16 KKK13525.1 - 3.6e-17 62.5 0.0 5.2e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK13525.1 - 2.7e-08 32.8 0.0 5.3e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KKK13525.1 - 1e-05 25.5 0.0 3e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK13525.1 - 0.016 14.8 0.0 0.059 13.0 0.0 1.8 2 0 0 2 2 2 0 KR domain Ldh_1_N PF00056.18 KKK13525.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KKK13525.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF605 PF04652.11 KKK13527.1 - 2.9e-95 319.8 6.8 1e-88 298.3 3.0 2.0 2 0 0 2 2 2 2 Vta1 like MSA_2 PF00985.12 KKK13527.1 - 0.035 14.2 1.8 0.035 14.2 1.2 2.0 1 1 2 3 3 3 0 Merozoite Surface Antigen 2 (MSA-2) family Mito_carr PF00153.22 KKK13528.1 - 7.9e-55 182.5 2.7 8.1e-22 76.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fibrinogen_aC PF12160.3 KKK13528.1 - 0.017 14.5 2.1 2.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Fibrinogen alpha C domain Peptidase_C2 PF00648.16 KKK13529.1 - 2.3e-23 82.6 0.0 8.3e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.17 KKK13529.1 - 1.5e-16 60.3 0.0 3.1e-14 52.8 0.0 3.5 3 2 0 3 3 3 1 Calpain large subunit, domain III MIT PF04212.13 KKK13529.1 - 6.5e-09 35.5 1.7 1.1e-08 34.7 1.2 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF1793 PF08760.6 KKK13531.1 - 4.4e-74 247.9 0.3 1.4e-73 246.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) BSP_II PF05432.6 KKK13533.1 - 0.0015 17.8 8.9 0.0018 17.6 6.2 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Daxx PF03344.10 KKK13533.1 - 0.0039 15.7 13.8 0.0041 15.7 9.6 1.0 1 0 0 1 1 1 1 Daxx Family eIF-3c_N PF05470.7 KKK13533.1 - 0.013 13.6 7.2 0.014 13.5 5.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TFIIF_alpha PF05793.7 KKK13533.1 - 0.043 12.1 11.7 0.051 11.9 8.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SpoIIIAH PF12685.2 KKK13533.1 - 0.053 12.9 9.3 0.1 12.0 6.4 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.7 KKK13533.1 - 0.19 9.6 14.8 0.22 9.4 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.6 KKK13533.1 - 0.22 10.5 17.4 0.28 10.2 12.0 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CENP-B_dimeris PF09026.5 KKK13533.1 - 0.26 11.5 16.0 2.2 8.5 6.7 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SDA1 PF05285.7 KKK13533.1 - 0.41 9.8 13.0 0.54 9.4 9.0 1.1 1 0 0 1 1 1 0 SDA1 DUF1675 PF07897.6 KKK13533.1 - 0.48 10.2 5.4 0.63 9.8 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDC45 PF02724.9 KKK13533.1 - 0.57 8.1 13.5 0.69 7.8 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 KKK13533.1 - 0.6 9.2 20.1 0.67 9.1 13.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sporozoite_P67 PF05642.6 KKK13533.1 - 0.74 7.6 6.7 0.96 7.2 4.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ORC6 PF05460.8 KKK13533.1 - 0.95 8.4 13.1 1.2 8.1 9.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1510 PF07423.6 KKK13533.1 - 1.3 8.3 18.9 1.8 7.9 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MCPVI PF02993.9 KKK13533.1 - 1.4 9.0 9.3 1.8 8.6 6.5 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Prp19_bind PF06991.6 KKK13533.1 - 2.2 7.4 15.7 2.9 7.0 10.9 1.2 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Red1 PF07964.6 KKK13533.1 - 2.6 6.1 14.5 3 5.8 10.0 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Lin-8 PF03353.10 KKK13533.1 - 2.7 7.1 12.9 3.3 6.8 8.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Bud13 PF09736.4 KKK13533.1 - 3.5 7.8 14.1 5.3 7.2 9.8 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Hid1 PF12722.2 KKK13533.1 - 3.8 5.0 13.3 4.5 4.8 9.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_DNAp_acc PF04929.7 KKK13533.1 - 3.9 6.3 12.4 4.9 6.0 8.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SAPS PF04499.10 KKK13533.1 - 4.9 5.6 9.9 5.5 5.5 6.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF605 PF04652.11 KKK13533.1 - 6.9 5.9 19.5 8.6 5.6 13.5 1.1 1 0 0 1 1 1 0 Vta1 like Neur_chan_memb PF02932.11 KKK13533.1 - 7.2 6.4 5.5 7.8 6.3 3.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 KKK13533.1 - 7.5 6.2 7.9 10 5.8 5.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Tom37_C PF11801.3 KKK13533.1 - 7.8 6.3 15.5 1.8e+02 1.9 10.8 2.0 1 1 0 1 1 1 0 Tom37 C-terminal domain DEAD PF00270.24 KKK13534.1 - 1.4e-41 141.8 0.0 2.2e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK13534.1 - 1e-25 89.3 0.0 2.4e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK13534.1 - 0.0013 18.6 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KKK13534.1 - 0.013 14.2 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain CTNNBL PF08216.6 KKK13534.1 - 0.1 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear HCO3_cotransp PF00955.16 KKK13535.1 - 1.8e-69 234.7 12.0 9.9e-42 143.2 2.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family zf-CCHC PF00098.18 KKK13536.1 - 4.3e-12 45.3 9.7 1e-05 25.2 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 KKK13536.1 - 5.4e-07 29.2 5.9 0.00037 20.1 1.9 2.3 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 KKK13536.1 - 0.00043 19.8 6.0 0.16 11.6 0.5 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 KKK13536.1 - 0.0062 16.1 11.8 0.23 11.1 0.4 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.1 KKK13536.1 - 0.033 13.6 0.2 0.033 13.6 0.1 3.4 2 1 1 3 3 3 0 Zinc knuckle Mito_fiss_reg PF05308.6 KKK13537.1 - 0.014 14.8 1.2 0.014 14.8 0.8 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF3237 PF11578.3 KKK13565.1 - 3.8e-38 130.1 0.0 4.2e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) adh_short PF00106.20 KKK13566.1 - 5.9e-15 55.5 0.1 9.1e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK13566.1 - 0.00045 19.9 0.1 0.00058 19.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KKK13566.1 - 0.0075 15.2 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THUMP PF02926.12 KKK13567.1 - 1.8e-12 47.3 1.1 3.4e-12 46.4 0.1 1.7 2 0 0 2 2 2 1 THUMP domain TPP_enzyme_N PF02776.13 KKK13568.1 - 4.7e-35 120.5 0.0 8.1e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KKK13568.1 - 9.5e-27 93.4 0.1 3.3e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KKK13568.1 - 4.5e-15 55.5 0.0 1.5e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KKK13568.1 - 0.003 16.3 0.1 0.0053 15.5 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Inhibitor_I78 PF11720.3 KKK13568.1 - 0.14 11.9 0.1 3.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Peptidase inhibitor I78 family TraL PF07178.6 KKK13569.1 - 0.014 15.4 3.2 2.8 8.0 0.1 3.5 3 0 0 3 3 3 0 TraL protein GMC_oxred_N PF00732.14 KKK13570.1 - 1.4e-51 175.3 0.0 2e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK13570.1 - 3.7e-34 118.0 0.0 6.3e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KKK13570.1 - 3e-05 23.1 0.2 0.0011 17.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK13570.1 - 6.4e-05 21.9 0.0 0.087 11.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KKK13570.1 - 0.0023 17.8 0.1 0.0093 15.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK13570.1 - 0.0047 15.9 0.1 0.0079 15.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KKK13570.1 - 0.0078 16.1 0.1 0.031 14.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.18 KKK13570.1 - 0.25 10.8 3.8 5.9 6.3 0.3 3.4 3 0 0 3 3 3 0 FAD binding domain RCC1 PF00415.13 KKK13571.1 - 4.8e-22 77.9 9.9 4.3e-05 23.6 0.1 7.0 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KKK13571.1 - 5.2e-14 51.4 11.2 4.8e-10 38.7 0.0 5.3 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat PUF PF00806.14 KKK13572.1 - 2.1e-16 58.3 0.0 0.028 13.8 0.0 7.7 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat TPR_18 PF13512.1 KKK13572.1 - 0.044 13.7 0.1 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KKK13573.1 - 9.5e-66 221.5 0.0 1.6e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13573.1 - 5.7e-44 150.1 0.0 8.2e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13573.1 - 3.6e-09 36.0 0.0 3.3e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KKK13573.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec34 PF04136.10 KKK13574.1 - 2.2e-26 92.4 1.5 4.6e-26 91.4 0.6 1.9 2 0 0 2 2 2 1 Sec34-like family NPV_P10 PF05531.7 KKK13574.1 - 0.076 13.2 0.1 4.4 7.6 0.0 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exo70 PF03081.10 KKK13574.1 - 0.19 10.4 6.6 0.37 9.5 0.0 3.5 4 0 0 4 4 4 0 Exo70 exocyst complex subunit Metallopep PF12044.3 KKK13575.1 - 2e-174 580.0 0.0 3.3e-174 579.3 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KKK13575.1 - 3.6e-05 23.6 0.0 0.0056 16.5 0.0 2.4 1 1 1 2 2 2 2 Jacalin-like lectin domain Reprolysin_5 PF13688.1 KKK13575.1 - 0.025 14.5 0.4 0.054 13.4 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KKK13575.1 - 0.047 13.2 0.2 0.093 12.2 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like NACHT PF05729.7 KKK13576.1 - 2.8e-07 30.3 0.0 7.1e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KKK13576.1 - 5.4e-05 23.2 0.0 0.00019 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK13576.1 - 0.007 16.5 0.5 0.038 14.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain DNA_ligase_A_M PF01068.16 KKK13577.1 - 1.5e-51 174.6 0.1 1.2e-48 165.1 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KKK13577.1 - 1.4e-41 142.2 0.0 2.8e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KKK13577.1 - 6.2e-19 68.1 0.1 4.3e-18 65.5 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Whi5 PF08528.6 KKK13578.1 - 0.044 13.4 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 Whi5 like AAA PF00004.24 KKK13579.1 - 1.2e-18 67.6 0.0 2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK13579.1 - 0.0028 17.8 0.5 0.017 15.2 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK13579.1 - 0.027 14.7 0.1 0.088 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KKK13579.1 - 0.031 14.2 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KKK13579.1 - 0.048 14.4 0.2 0.37 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KKK13579.1 - 0.093 11.8 0.1 0.19 10.7 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 KKK13579.1 - 0.097 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 KKK13579.1 - 0.31 10.1 1.1 0.72 8.9 0.2 1.9 1 1 1 2 2 2 0 KaiC RINT1_TIP1 PF04437.8 KKK13580.1 - 3.4e-191 636.0 0.0 2.7e-190 633.1 0.0 2.0 2 0 0 2 2 2 1 RINT-1 / TIP-1 family TPR_16 PF13432.1 KKK13580.1 - 0.0044 17.6 4.3 0.018 15.6 3.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK13580.1 - 0.0065 16.0 1.3 0.018 14.7 0.9 1.7 1 0 0 1 1 1 1 TPR repeat Hemerythrin PF01814.18 KKK13580.1 - 0.057 13.5 5.0 0.98 9.5 0.5 3.3 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain DivIVA PF05103.8 KKK13580.1 - 3.3 7.7 11.8 2.7 8.0 6.6 2.0 2 0 0 2 2 2 0 DivIVA protein TPR_14 PF13428.1 KKK13580.1 - 8.4 7.3 7.7 7.7 7.4 2.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Pyridoxal_deC PF00282.14 KKK13581.1 - 5.4e-78 262.0 0.0 6.1e-77 258.5 0.0 2.3 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KKK13581.1 - 6e-07 28.5 0.0 9.8e-07 27.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KKK13581.1 - 1.6e-05 24.1 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF814 PF05670.8 KKK13581.1 - 0.054 13.3 0.0 16 5.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF814) SLA_LP_auto_ag PF05889.8 KKK13581.1 - 0.12 10.7 0.0 0.23 9.9 0.0 1.4 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Nuc_sug_transp PF04142.10 KKK13582.1 - 1.3e-64 217.6 5.2 2.9e-64 216.5 3.6 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter Sec63 PF02889.11 KKK13582.1 - 7.9e-51 173.1 0.0 1.2e-50 172.5 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KKK13582.1 - 2.2e-28 98.8 0.0 4.8e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KKK13582.1 - 1.5e-10 41.2 0.0 2.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK13582.1 - 3.1e-07 30.1 0.0 1.4e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain EamA PF00892.15 KKK13582.1 - 9e-05 22.5 23.7 0.00025 21.0 5.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family AAA_22 PF13401.1 KKK13582.1 - 0.00022 21.3 0.1 0.00072 19.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain EmrE PF13536.1 KKK13582.1 - 0.00022 21.4 3.6 0.00022 21.4 2.5 2.5 2 0 0 2 2 2 1 Multidrug resistance efflux transporter SNF2_N PF00176.18 KKK13582.1 - 0.00035 19.4 0.1 0.00068 18.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 KKK13582.1 - 0.023 14.4 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 KKK13582.1 - 0.046 12.6 0.0 0.096 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 KKK13582.1 - 0.069 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.1 KKK13582.1 - 0.16 12.1 0.0 0.68 10.1 0.0 2.0 2 0 0 2 2 1 0 Helix-hairpin-helix domain TPT PF03151.11 KKK13582.1 - 0.51 9.9 18.0 0.08 12.5 1.6 2.7 2 0 0 2 2 2 0 Triose-phosphate Transporter family LRR_4 PF12799.2 KKK13583.1 - 9.5e-07 28.3 3.3 0.00014 21.3 0.2 3.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KKK13583.1 - 3e-05 23.6 0.9 0.87 9.8 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 KKK13583.1 - 7.4e-05 22.2 0.7 3.1 8.1 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.1 KKK13583.1 - 0.00012 21.7 2.6 0.0033 17.1 0.8 3.3 2 1 1 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 KKK13583.1 - 0.0026 17.6 0.1 9 7.0 0.0 3.8 3 0 0 3 3 3 2 Leucine rich repeat HORMA PF02301.13 KKK13584.1 - 1.2e-54 184.9 0.0 1.8e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 KKK13584.1 - 0.0057 16.3 7.4 0.011 15.3 5.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KKK13584.1 - 0.27 10.6 6.3 0.75 9.1 4.5 1.8 1 1 0 1 1 1 0 PHD-finger MMR_HSR1 PF01926.18 KKK13586.1 - 1.3e-19 70.2 0.0 1.9e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KKK13586.1 - 1.2e-05 25.1 0.0 0.0002 21.2 0.0 2.2 1 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 KKK13586.1 - 0.00093 18.5 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KKK13586.1 - 0.0011 18.4 0.0 0.01 15.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KKK13586.1 - 0.0036 16.4 0.0 0.0064 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KKK13586.1 - 0.0067 15.5 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_33 PF13671.1 KKK13586.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK13586.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KKK13586.1 - 0.022 15.0 0.1 0.036 14.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 KKK13586.1 - 0.041 13.1 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 KKK13586.1 - 0.12 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein WD40 PF00400.27 KKK13587.1 - 3.3e-55 182.1 17.3 2.1e-09 36.8 0.3 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KKK13587.1 - 1.4e-08 34.3 0.1 2.8e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK13587.1 - 2.1e-07 30.4 0.4 4.8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 KKK13587.1 - 0.0028 15.8 7.5 0.38 8.8 0.1 4.7 2 2 3 6 6 6 3 Nucleoporin Nup120/160 CPSF_A PF03178.10 KKK13587.1 - 0.095 11.7 0.0 0.35 9.9 0.0 1.8 3 0 0 3 3 3 0 CPSF A subunit region Clat_adaptor_s PF01217.15 KKK13588.1 - 2.6e-42 143.9 1.1 7.8e-42 142.3 0.0 2.3 3 1 0 3 3 3 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.21 KKK13588.1 - 6.9e-23 79.9 0.9 1.2e-22 79.1 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Med13_C PF06333.7 KKK13598.1 - 8.4e-118 393.5 0.0 1.3e-117 392.9 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KKK13598.1 - 2.1e-83 280.2 0.0 3.3e-83 279.6 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 KKK13599.1 - 4.1e-12 45.4 0.4 9.3e-12 44.3 0.3 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KKK13599.1 - 1.6e-07 30.9 0.0 0.012 15.5 0.0 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_60s PF00428.14 KKK13599.1 - 1.6 9.1 6.9 4.3 7.7 4.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein RCC1 PF00415.13 KKK13600.1 - 7.9e-23 80.4 0.5 9e-06 25.8 0.0 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KKK13600.1 - 3e-15 56.1 0.2 9.2e-09 35.2 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 KKK13600.1 - 5.6e-13 48.1 3.3 7.3e-09 35.0 0.2 4.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 KKK13600.1 - 1.5e-05 25.3 0.3 0.00034 21.0 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK13600.1 - 0.00093 19.2 0.3 2.2 8.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KKK13600.1 - 0.0024 18.1 0.1 0.0074 16.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK13600.1 - 0.12 12.6 0.4 3.4 8.0 0.1 2.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) FAD_binding_6 PF00970.19 KKK13601.1 - 4.7e-30 103.6 0.0 6.9e-30 103.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KKK13601.1 - 2.6e-28 98.7 0.0 4.1e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KKK13601.1 - 1.2e-06 28.5 0.0 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KKK13601.1 - 0.00022 21.1 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4176 PF13780.1 KKK13601.1 - 0.029 14.0 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) DUF3605 PF12239.3 KKK13602.1 - 2.8e-53 180.0 0.0 3.8e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) SMC_N PF02463.14 KKK13603.1 - 1.3e-72 243.5 0.0 2.1e-72 242.9 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KKK13603.1 - 3.8e-33 113.9 0.0 2.9e-32 111.1 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KKK13603.1 - 9.6e-19 68.4 2.4 1.9e-09 37.8 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 KKK13603.1 - 1.1e-14 55.2 20.6 1.1e-14 55.2 14.3 6.9 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.1 KKK13603.1 - 8.1e-09 35.0 1.7 8.1e-09 35.0 1.2 3.7 2 2 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 KKK13603.1 - 0.00032 20.1 0.0 0.00076 18.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6 PF04111.7 KKK13603.1 - 0.00037 19.6 8.9 0.00037 19.6 6.1 7.3 2 2 3 7 7 7 3 Autophagy protein Apg6 MCPsignal PF00015.16 KKK13603.1 - 0.0022 17.5 3.4 0.0022 17.5 2.3 6.4 6 1 0 6 6 6 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Reo_sigmaC PF04582.7 KKK13603.1 - 0.0094 15.1 32.4 0.2 10.8 1.1 5.4 2 2 2 5 5 5 4 Reovirus sigma C capsid protein FliD_N PF02465.13 KKK13603.1 - 0.011 16.0 1.8 0.011 16.0 1.3 8.0 3 3 5 9 9 8 0 Flagellar hook-associated protein 2 N-terminus FtsK_SpoIIIE PF01580.13 KKK13603.1 - 0.26 10.7 0.0 0.26 10.7 0.0 4.1 4 1 0 4 4 4 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KKK13603.1 - 0.42 10.8 0.0 0.42 10.8 0.0 6.1 3 2 0 3 3 1 0 ABC transporter RIO1 PF01163.17 KKK13604.1 - 2.1e-74 248.9 0.1 2.1e-74 248.9 0.1 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KKK13604.1 - 0.0043 16.8 0.0 1.2 8.8 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family ABC_tran PF00005.22 KKK13605.1 - 2.5e-26 92.5 0.5 3.8e-26 92.0 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 KKK13605.1 - 1.4e-07 31.7 0.1 0.00032 20.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK13605.1 - 2.2e-05 24.5 0.9 2.8e-05 24.1 0.1 1.8 2 1 0 2 2 1 1 AAA ATPase domain DUF258 PF03193.11 KKK13605.1 - 3e-05 23.2 0.1 5.8e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KKK13605.1 - 3.3e-05 23.3 0.0 0.00017 21.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK13605.1 - 3.8e-05 24.4 0.0 9.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK13605.1 - 0.00011 22.3 0.1 0.00079 19.6 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 KKK13605.1 - 0.00012 21.3 0.0 0.00028 20.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 KKK13605.1 - 0.0002 21.1 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_15 PF13175.1 KKK13605.1 - 0.00021 20.5 0.0 0.029 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK13605.1 - 0.0006 19.9 0.1 0.0029 17.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KKK13605.1 - 0.0011 18.6 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 KKK13605.1 - 0.0013 18.5 0.0 0.0043 16.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KKK13605.1 - 0.0016 18.1 0.1 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KKK13605.1 - 0.002 18.1 0.2 0.0046 16.9 0.2 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KKK13605.1 - 0.0021 17.5 0.6 0.0058 16.0 0.0 2.0 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 KKK13605.1 - 0.0024 18.1 0.0 0.0064 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KKK13605.1 - 0.0032 16.2 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KKK13605.1 - 0.0036 17.4 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.1 KKK13605.1 - 0.0038 17.1 0.0 0.0079 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KKK13605.1 - 0.0058 16.1 0.2 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 KKK13605.1 - 0.006 16.3 0.0 0.042 13.5 0.0 2.2 2 0 0 2 2 2 1 NTPase MMR_HSR1 PF01926.18 KKK13605.1 - 0.0083 16.0 0.1 0.025 14.5 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_13 PF13166.1 KKK13605.1 - 0.0097 14.4 0.7 0.11 10.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KKK13605.1 - 0.0098 15.6 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KKK13605.1 - 0.016 14.0 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 KKK13605.1 - 0.018 14.5 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 KKK13605.1 - 0.018 14.5 0.0 0.049 13.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 KKK13605.1 - 0.019 14.0 0.0 0.04 12.9 0.0 1.5 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 KKK13605.1 - 0.023 14.3 0.1 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KKK13605.1 - 0.031 13.7 0.1 0.06 12.8 0.1 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 KKK13605.1 - 0.037 13.9 0.0 0.19 11.6 0.0 2.3 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 KKK13605.1 - 0.038 12.8 0.0 0.082 11.7 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain ArgK PF03308.11 KKK13605.1 - 0.047 12.4 0.1 0.092 11.5 0.1 1.4 1 0 0 1 1 1 0 ArgK protein AAA_35 PF14516.1 KKK13605.1 - 0.058 12.0 0.0 0.097 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 KKK13605.1 - 0.066 12.9 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KKK13605.1 - 0.075 12.6 1.1 0.088 12.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 KKK13605.1 - 0.081 12.3 0.2 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 KKK13605.1 - 0.11 11.9 0.1 0.25 10.7 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain tRNA-synt_1d PF00750.14 KKK13606.1 - 1.2e-82 277.6 4.3 6.4e-46 156.7 1.7 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 KKK13606.1 - 8.5e-28 96.7 1.7 1.1e-27 96.2 0.0 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KKK13606.1 - 5e-05 23.7 0.4 0.00028 21.3 0.0 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain FlgN PF05130.7 KKK13606.1 - 0.04 14.1 0.5 0.12 12.6 0.3 1.7 1 0 0 1 1 1 0 FlgN protein FliD_N PF02465.13 KKK13606.1 - 0.42 11.0 2.8 1.2 9.5 1.5 2.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus CENP-C_C PF11699.3 KKK13613.1 - 3.5e-36 123.0 0.4 6.9e-36 122.1 0.3 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 KKK13613.1 - 2.2e-34 118.9 6.6 2.5e-24 86.3 0.6 4.8 2 1 3 5 5 5 2 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 KKK13613.1 - 8.4e-08 31.6 0.0 2.6e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Cupin domain F-box-like PF12937.2 KKK13614.1 - 6.5e-09 35.3 0.3 1.5e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK13614.1 - 9.1e-09 34.7 1.3 1.9e-08 33.7 0.9 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 KKK13614.1 - 5.9e-06 25.9 0.7 0.25 11.3 0.0 3.4 2 0 0 2 2 2 2 WD domain, G-beta repeat SAE2 PF08573.5 KKK13615.1 - 5.9e-32 110.2 3.3 7.5e-32 109.9 0.1 2.8 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4200 PF13863.1 KKK13615.1 - 0.0058 16.5 7.3 0.0058 16.5 5.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) Pex16 PF08610.5 KKK13616.1 - 2e-113 378.8 0.0 2.3e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 KKK13617.1 - 1.1e-45 155.7 0.0 1.4e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII DUF3280 PF11684.3 KKK13617.1 - 0.008 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) Ribosomal_L31e PF01198.14 KKK13617.1 - 0.14 11.7 0.1 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L31e Aldo_ket_red PF00248.16 KKK13619.1 - 1.9e-48 164.6 0.0 2.4e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 KKK13620.1 - 5.9e-122 407.4 0.0 7.3e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TOBE PF03459.12 KKK13620.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 TOBE domain zf-CCHC PF00098.18 KKK13621.1 - 3e-50 165.8 64.0 4.4e-09 35.8 1.0 7.5 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_4 PF14392.1 KKK13621.1 - 1.5e-14 53.3 43.5 0.014 15.0 0.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KKK13621.1 - 4.2e-05 23.1 47.2 0.018 14.7 0.4 6.6 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 KKK13621.1 - 0.00027 20.5 56.8 0.017 14.8 1.3 7.6 6 2 2 8 8 8 5 Zinc knuckle SelR PF01641.13 KKK13621.1 - 2.9 7.6 7.1 0.53 9.9 1.1 2.3 2 1 0 2 2 2 0 SelR domain zf-CCHC_2 PF13696.1 KKK13621.1 - 8.8 5.9 41.8 0.7 9.4 0.1 7.0 3 2 4 7 7 7 0 Zinc knuckle Adeno_E3_CR2 PF02439.10 KKK13633.1 - 0.27 10.7 1.0 0.49 9.9 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1992 PF09350.5 KKK13634.1 - 9e-25 86.3 1.1 1.5e-24 85.5 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) TAFII28 PF04719.9 KKK13635.1 - 1e-19 70.0 0.1 2e-19 69.1 0.0 1.5 2 0 0 2 2 2 1 hTAFII28-like protein conserved region FrpC PF06901.7 KKK13635.1 - 0.17 11.3 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 RTX iron-regulated protein FrpC Mid2 PF04478.7 KKK13637.1 - 0.00096 18.5 0.0 0.0027 17.1 0.0 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor YopJ PF03421.11 KKK13637.1 - 0.095 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase FAD_binding_4 PF01565.18 KKK13638.1 - 1.3e-24 86.2 0.2 2e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK13638.1 - 0.0012 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Hydrolase_like2 PF13246.1 KKK13639.1 - 0.018 14.9 0.2 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Pro_isomerase PF00160.16 KKK13640.1 - 1.1e-44 152.3 1.8 2.8e-44 151.0 1.2 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CBM_4_9 PF02018.12 KKK13641.1 - 2.1e-10 40.7 0.1 2.5e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate binding domain TDH PF03347.8 KKK13641.1 - 0.029 13.8 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin Spherulin4 PF12138.3 KKK13641.1 - 0.062 12.7 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 Sugar_tr PF00083.19 KKK13642.1 - 2.4e-39 135.1 36.0 2.7e-25 88.8 8.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK13642.1 - 9.3e-24 83.7 41.0 2.7e-12 46.1 12.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KKK13642.1 - 0.018 14.8 3.4 0.15 11.9 0.1 3.8 4 1 0 4 4 4 0 MFS_1 like family ATP_synt_H PF05493.8 KKK13642.1 - 0.37 10.8 6.0 6.2 6.9 1.1 3.6 3 0 0 3 3 3 0 ATP synthase subunit H PhyH PF05721.8 KKK13643.1 - 1.4e-27 97.1 0.0 2.2e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HD PF01966.17 KKK13643.1 - 4.8e-07 29.8 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 HD domain 2OG-FeII_Oxy_3 PF13640.1 KKK13643.1 - 0.0013 19.1 0.0 0.0033 17.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 KKK13643.1 - 0.0053 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF706 PF05153.10 KKK13643.1 - 0.0096 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF706) HDOD PF08668.7 KKK13643.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 HDOD domain Cellulase PF00150.13 KKK13644.1 - 1.3e-10 40.9 1.1 4.7e-06 26.0 0.0 2.5 2 1 1 3 3 3 2 Cellulase (glycosyl hydrolase family 5) APH PF01636.18 KKK13651.1 - 0.0053 16.5 0.3 0.079 12.6 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF2371 PF10177.4 KKK13653.1 - 0.086 12.7 0.2 0.18 11.6 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF508 PF04370.7 KKK13653.1 - 4.1 7.0 10.5 0.063 12.9 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF508) Myco_19_kDa PF05481.7 KKK13653.1 - 4.5 7.0 9.0 0.17 11.7 1.5 2.0 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen Piwi PF02171.12 KKK13654.1 - 2.9e-73 246.4 0.0 5.7e-73 245.5 0.0 1.5 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KKK13654.1 - 8.2e-14 50.7 0.1 1.8e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KKK13654.1 - 6.9e-13 48.0 0.0 3.8e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 PAZ domain MFS_1 PF07690.11 KKK13655.1 - 3.2e-33 114.9 25.5 3.2e-33 114.9 17.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Phosducin PF02114.11 KKK13656.1 - 2.8e-06 26.2 0.0 3.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Phosducin DLIC PF05783.6 KKK13661.1 - 1.2e-38 133.0 0.2 4.7e-35 121.1 0.0 3.3 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) RRM_1 PF00076.17 KKK13662.1 - 2e-19 68.9 0.0 4.7e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13662.1 - 3e-12 46.3 0.0 7.3e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK13662.1 - 2.8e-06 27.0 0.0 4.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KKK13663.1 - 2.3e-08 33.5 0.2 0.0042 16.9 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.7 KKK13663.1 - 0.0011 16.9 0.0 0.0015 16.4 0.0 1.1 1 0 0 1 1 1 1 IKI3 family EMP70 PF02990.11 KKK13679.1 - 1.3e-153 512.1 0.0 3.5e-153 510.8 0.0 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.18 KKK13680.1 - 2.5e-19 68.4 0.0 4.1e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KKK13680.1 - 3.9e-09 36.0 0.1 1.3e-08 34.4 0.1 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 KKK13680.1 - 3.4e-08 33.0 0.0 5.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 KKK13680.1 - 3.4e-05 24.3 0.0 6.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF2407 PF10302.4 KKK13680.1 - 6.7e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KKK13680.1 - 7.6e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KKK13680.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain BP28CT PF08146.7 KKK13681.1 - 7e-46 155.7 0.3 3.1e-45 153.6 0.2 2.3 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KKK13681.1 - 1.1e-33 115.7 10.8 3.4e-30 104.4 0.7 5.8 7 0 0 7 7 7 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 KKK13681.1 - 4.9e-10 39.5 4.9 0.011 16.0 0.1 5.6 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.17 KKK13681.1 - 8.5e-06 25.4 4.0 0.046 13.8 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat NRDE-2 PF08424.5 KKK13682.1 - 2.3e-96 322.4 2.7 5.5e-95 317.9 1.5 2.4 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KKK13682.1 - 0.02 15.5 0.0 7 7.5 0.0 4.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK13682.1 - 0.026 15.2 0.2 1.1 9.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Corona_nucleoca PF00937.13 KKK13682.1 - 1.9 7.3 10.7 3.3 6.5 7.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CPSF_A PF03178.10 KKK13683.1 - 5.6e-100 334.5 0.0 9.9e-99 330.4 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KKK13683.1 - 1.3e-69 234.7 0.0 2.2e-69 233.9 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 KKK13683.1 - 0.0036 16.9 0.0 1.8 8.1 0.0 3.2 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal YmzC PF14157.1 KKK13683.1 - 0.19 11.5 0.0 0.78 9.6 0.0 2.1 1 0 0 1 1 1 0 YmzC-like protein WD40 PF00400.27 KKK13683.1 - 0.38 10.7 1.3 0.85 9.5 0.1 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat Bul1_N PF04425.7 KKK13684.1 - 1.8e-13 49.8 2.6 5.2e-09 35.1 1.3 2.5 2 1 0 2 2 2 2 Bul1 N terminus Arrestin_N PF00339.24 KKK13684.1 - 0.00034 20.4 0.0 0.00065 19.5 0.0 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 KKK13684.1 - 0.013 14.6 0.4 0.026 13.7 0.1 1.5 2 0 0 2 2 2 0 Bul1 C terminus NAD_binding_6 PF08030.7 KKK13685.1 - 1.9e-22 79.8 0.0 3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KKK13685.1 - 6.3e-22 77.4 0.0 1.4e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KKK13685.1 - 1.7e-18 66.9 11.0 4.5e-18 65.5 7.6 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KKK13685.1 - 6.6e-05 22.9 0.0 0.0002 21.4 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Sulfatase PF00884.18 KKK13687.1 - 5.4e-58 196.6 0.2 7e-58 196.2 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KKK13687.1 - 5.3e-21 74.1 0.1 1.2e-20 73.0 0.1 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KKK13687.1 - 4.4e-11 42.7 0.1 9.4e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KKK13687.1 - 0.0084 14.5 0.0 0.011 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 KKK13687.1 - 0.014 15.6 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 KKK13687.1 - 0.035 12.9 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Tim44 PF04280.10 KKK13688.1 - 3.5e-34 117.9 0.0 1.3e-33 116.0 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain FAM176 PF14851.1 KKK13688.1 - 0.079 12.6 4.7 0.28 10.8 3.4 1.7 2 0 0 2 2 2 0 FAM176 family CutA1 PF03091.10 KKK13688.1 - 0.11 12.1 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein TPR_11 PF13414.1 KKK13689.1 - 3e-20 71.6 9.6 1.6e-16 59.7 3.0 2.5 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KKK13689.1 - 8.5e-13 47.3 6.7 0.00063 19.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KKK13689.1 - 5.1e-12 44.7 9.0 0.0039 17.0 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK13689.1 - 5.4e-07 30.1 11.6 2.4e-05 24.8 4.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK13689.1 - 1.7e-06 27.7 0.8 0.002 18.1 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK13689.1 - 3.3e-05 23.3 1.2 1.6 8.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK13689.1 - 6.3e-05 23.2 4.6 0.00017 21.8 2.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat XPC-binding PF09280.6 KKK13689.1 - 0.00026 20.3 6.2 0.00026 20.3 3.0 1.9 2 0 0 2 2 2 1 XPC-binding domain TPR_14 PF13428.1 KKK13689.1 - 0.00048 20.5 7.3 0.12 13.0 0.2 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 KKK13689.1 - 0.00052 19.8 4.7 0.015 15.1 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK13689.1 - 0.0011 18.8 7.6 0.11 12.3 0.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK13689.1 - 0.0011 18.5 8.1 0.065 13.0 0.1 4.1 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KKK13689.1 - 5.4 7.0 8.9 1.7 8.6 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK13689.1 - 9.4 6.9 8.8 6 7.5 0.2 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat RIC1 PF07064.8 KKK13690.1 - 1.2e-90 303.5 0.0 1.7e-90 303.0 0.0 1.2 1 0 0 1 1 1 1 RIC1 Ank_5 PF13857.1 KKK13691.1 - 1.9e-19 69.2 0.2 5.4e-10 39.1 0.0 5.7 6 1 1 7 7 7 3 Ankyrin repeats (many copies) VPS9 PF02204.13 KKK13691.1 - 6.2e-16 58.3 0.0 1.4e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 KKK13691.1 - 8.3e-14 51.7 0.5 6.9e-05 23.1 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK13691.1 - 1.7e-09 37.8 0.2 0.0098 16.3 0.0 4.9 1 1 2 4 4 4 3 Ankyrin repeats (many copies) PX PF00787.19 KKK13691.1 - 3.6e-09 36.4 2.6 4.9e-09 35.9 0.4 2.2 2 0 0 2 2 2 1 PX domain Ank_3 PF13606.1 KKK13691.1 - 1.1e-08 34.4 0.2 2 8.9 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 KKK13691.1 - 3.7e-07 29.6 0.4 0.095 12.5 0.0 5.2 6 0 0 6 6 6 2 Ankyrin repeat FAST_2 PF08368.7 KKK13691.1 - 0.046 14.1 0.0 0.2 12.0 0.0 2.2 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Ribosomal_S11 PF00411.14 KKK13692.1 - 7.2e-07 29.3 0.0 2.2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S11 Myc_N PF01056.13 KKK13721.1 - 0.0035 16.5 0.1 0.0063 15.7 0.0 1.4 1 0 0 1 1 1 1 Myc amino-terminal region MutS_I PF01624.15 KKK13722.1 - 3.5e-12 46.3 0.0 5.6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain I CDC27 PF09507.5 KKK13722.1 - 8.6 5.4 17.4 2.5 7.2 0.5 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 RhoGAP PF00620.22 KKK13723.1 - 5.3e-30 104.0 0.0 9e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.16 KKK13724.1 - 2.5e-51 170.8 10.4 1.1e-11 44.0 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KKK13724.1 - 7.7e-28 97.1 0.0 3.3e-11 43.6 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KKK13724.1 - 1.5e-08 34.6 0.0 0.00065 19.6 0.0 3.4 1 1 1 3 3 3 2 Prenyltransferase-like RRS1 PF04939.7 KKK13725.1 - 9.9e-60 200.7 1.8 1.2e-59 200.5 1.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Acyl_transf_1 PF00698.16 KKK13726.1 - 3.2e-82 276.4 0.0 4.7e-81 272.5 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KKK13726.1 - 1e-39 134.7 0.0 2.7e-39 133.3 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KKK13726.1 - 2.1e-30 104.2 0.1 5.7e-30 102.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KKK13726.1 - 1.9e-20 73.0 0.1 9.1e-20 70.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Kdo PF06293.9 KKK13727.1 - 4.4e-05 22.6 0.0 0.00011 21.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK13727.1 - 0.00077 19.2 6.3 0.0017 18.1 0.0 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK13727.1 - 0.0035 16.9 0.9 0.0084 15.7 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 KKK13727.1 - 0.0078 15.3 0.0 0.02 14.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain AAA_23 PF13476.1 KKK13727.1 - 2.4 8.4 9.8 35 4.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.1 KKK13727.1 - 8.6 4.8 11.6 29 3.0 8.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Pox_MCEL PF03291.11 KKK13728.1 - 3.4e-59 200.3 0.0 3.3e-39 134.6 0.0 3.7 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 KKK13728.1 - 4.9e-07 30.1 0.0 5.2e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK13728.1 - 1.8e-06 28.3 0.0 0.041 14.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KKK13728.1 - 1.3e-05 25.7 0.0 2.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK13728.1 - 2.4e-05 24.0 0.0 5.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK13728.1 - 7.1e-05 22.4 0.0 0.027 14.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KKK13728.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ribosomal_60s PF00428.14 KKK13728.1 - 0.029 14.7 0.9 0.029 14.7 0.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Methyltransf_25 PF13649.1 KKK13728.1 - 0.033 14.5 0.0 0.14 12.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 KKK13729.1 - 1e-57 195.7 0.0 1.4e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 KKK13729.1 - 4.4e-13 48.6 0.0 8e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase GST_N_3 PF13417.1 KKK13730.1 - 2.7e-09 37.1 0.0 5.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK13730.1 - 8.9e-08 32.0 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK13730.1 - 0.00072 19.4 1.2 0.0013 18.6 0.2 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain zf-C3HC PF07967.8 KKK13731.1 - 5.4e-41 139.4 0.0 3.5e-38 130.4 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 KKK13731.1 - 3.5e-36 122.9 0.1 1.2e-32 111.6 0.0 2.5 2 0 0 2 2 2 2 Rsm1-like DM PF00751.13 KKK13731.1 - 0.13 11.8 0.2 3.9 7.0 0.1 2.3 2 0 0 2 2 2 0 DM DNA binding domain COX15-CtaA PF02628.10 KKK13732.1 - 2.2e-97 325.5 5.9 2.6e-97 325.3 4.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein FAD_binding_3 PF01494.14 KKK13734.1 - 1.2e-17 64.0 0.1 1e-06 28.0 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KKK13734.1 - 0.00041 20.3 0.1 0.001 19.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK13734.1 - 0.00073 18.5 0.3 0.015 14.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KKK13734.1 - 0.0041 16.2 0.0 0.42 9.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KKK13734.1 - 0.0072 15.2 0.1 0.013 14.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK13734.1 - 0.023 13.7 0.1 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KKK13734.1 - 0.034 13.0 0.9 4.2 6.2 0.1 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.22 KKK13734.1 - 0.05 13.9 0.6 0.28 11.5 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK13734.1 - 0.052 13.4 0.1 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_2 PF00152.15 KKK13735.1 - 3.5e-90 302.1 0.2 5.3e-90 301.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KKK13735.1 - 3.1e-13 49.3 0.1 6.9e-13 48.2 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KKK13735.1 - 1.3e-05 24.5 0.0 0.015 14.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Dynamin_N PF00350.18 KKK13736.1 - 4.3e-24 85.2 0.0 1e-23 84.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KKK13736.1 - 1.7e-21 76.2 0.0 1.7e-16 59.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KKK13736.1 - 0.00013 21.7 0.2 0.00043 20.1 0.1 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KKK13736.1 - 0.00038 20.3 0.0 0.0097 15.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK13736.1 - 0.0041 17.6 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 KKK13736.1 - 0.015 14.1 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) CM_1 PF07736.6 KKK13736.1 - 0.036 14.1 0.0 0.88 9.6 0.0 2.5 2 0 0 2 2 2 0 Chorismate mutase type I AAA PF00004.24 KKK13737.1 - 1.3e-37 128.9 0.0 1.9e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK13737.1 - 8.4e-06 25.9 0.2 0.00011 22.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 KKK13737.1 - 2.2e-05 24.2 0.0 0.0002 21.1 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 KKK13737.1 - 3.9e-05 23.6 0.0 6.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KKK13737.1 - 6e-05 22.2 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KKK13737.1 - 0.00083 19.0 0.0 0.0022 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KKK13737.1 - 0.0018 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KKK13737.1 - 0.0018 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KKK13737.1 - 0.0024 16.6 0.0 0.0036 16.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KKK13737.1 - 0.0038 16.4 0.1 0.0078 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KKK13737.1 - 0.0045 16.4 0.2 0.12 11.7 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK13737.1 - 0.0078 16.2 4.1 0.0083 16.1 0.1 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 KKK13737.1 - 0.008 15.9 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KKK13737.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 KKK13737.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK13737.1 - 0.031 14.2 0.4 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KKK13737.1 - 0.032 15.0 0.6 0.097 13.4 0.0 2.2 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 KKK13737.1 - 0.032 13.6 0.0 0.35 10.3 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 KKK13737.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK13737.1 - 0.082 12.5 0.0 0.24 11.0 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 KKK13737.1 - 0.088 12.4 0.0 1.3 8.7 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase Guanylate_kin PF00625.16 KKK13737.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase PhoH PF02562.11 KKK13737.1 - 0.15 11.2 0.1 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ENTH PF01417.15 KKK13738.1 - 9.1e-44 148.3 0.0 1.6e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KKK13738.1 - 0.0085 14.8 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 KKK13738.1 - 0.038 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) UIM PF02809.15 KKK13738.1 - 0.055 13.0 5.2 0.074 12.6 0.9 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif WSC PF01822.14 KKK13761.1 - 3e-15 55.9 8.4 3e-15 55.9 5.8 2.3 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 KKK13761.1 - 1.6e-10 40.1 0.3 1.6e-10 40.1 0.2 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.8 KKK13761.1 - 0.00095 19.5 3.8 0.0016 18.7 2.6 1.4 1 0 0 1 1 1 1 Alphavirus glycoprotein J TrbL PF04610.9 KKK13761.1 - 0.16 11.6 1.8 0.25 11.0 1.3 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Pex14_N PF04695.8 KKK13761.1 - 0.29 11.1 3.8 0.67 10.0 2.7 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF515 PF04415.7 KKK13761.1 - 5.8 5.0 14.3 8 4.5 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SKN1 PF03935.10 KKK13762.1 - 4e-228 757.6 2.5 4.8e-228 757.3 1.8 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Sgf11 PF08209.6 KKK13766.1 - 2.8e-10 39.3 1.7 4.6e-10 38.6 0.1 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 KKK13766.1 - 0.017 14.7 0.6 0.032 13.9 0.4 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Tmemb_55A PF09788.4 KKK13766.1 - 0.38 9.8 5.0 0.12 11.5 1.3 1.7 1 1 1 2 2 2 0 Transmembrane protein 55A zf-C2HC5 PF06221.8 KKK13767.1 - 1.4e-21 75.9 4.9 2.2e-21 75.3 3.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Mpv17_PMP22 PF04117.7 KKK13768.1 - 2.4e-11 43.1 0.1 5.9e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 KKK13769.1 - 3.3e-08 32.6 11.7 3.3e-08 32.6 8.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Pacifastin_I PF05375.8 KKK13769.1 - 0.059 12.9 0.1 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) DUF1761 PF08570.5 KKK13769.1 - 2.4 8.1 13.1 8.2 6.4 5.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) 2TM PF13239.1 KKK13769.1 - 4.3 7.4 7.3 1.4 9.0 2.5 2.0 1 1 1 2 2 2 0 2TM domain RNase_PH PF01138.16 KKK13770.1 - 4.4e-17 62.6 1.9 3.5e-15 56.4 1.3 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_A22B PF04258.8 KKK13771.1 - 5e-55 187.0 0.0 3.7e-54 184.2 0.0 1.9 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KKK13771.1 - 2.8e-05 23.4 0.9 2.8e-05 23.4 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1119) Nucleoplasmin PF03066.10 KKK13771.1 - 0.00084 18.8 3.2 0.51 9.8 0.0 2.3 2 0 0 2 2 2 2 Nucleoplasmin FUSC_2 PF13515.1 KKK13771.1 - 0.059 13.2 0.2 0.059 13.2 0.2 2.6 2 0 0 2 2 2 0 Fusaric acid resistance protein-like FAM176 PF14851.1 KKK13771.1 - 1.3 8.7 0.0 1.3 8.7 0.0 3.5 2 1 2 4 4 4 0 FAM176 family SpoIIIAH PF12685.2 KKK13771.1 - 3.7 6.9 9.1 1.1e+02 2.1 0.0 2.6 2 1 0 2 2 2 0 SpoIIIAH-like protein Pro-rich PF15240.1 KKK13771.1 - 5.5 7.0 16.3 0.21 11.6 6.7 1.9 2 0 0 2 2 2 0 Proline-rich Acetyltransf_1 PF00583.19 KKK13772.1 - 1.7e-05 24.7 0.0 0.0039 17.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family NAD_binding_6 PF08030.7 KKK13773.1 - 1e-19 70.9 0.0 1.2e-18 67.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KKK13773.1 - 8.3e-19 67.9 12.1 1.9e-18 66.7 8.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KKK13773.1 - 8.7e-15 54.4 0.0 1.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KKK13773.1 - 0.0022 18.5 0.0 0.35 11.4 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF604 PF04646.7 KKK13774.1 - 2e-07 30.4 0.0 3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 KKK13774.1 - 1.4e-05 24.4 0.0 3e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Fringe-like Pro_isomerase PF00160.16 KKK13775.1 - 5e-52 176.2 0.1 5.7e-52 176.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GDI PF00996.13 KKK13776.1 - 8.6e-41 139.6 0.0 1.2e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor RRM_1 PF00076.17 KKK13777.1 - 2.8e-17 62.1 0.0 4.1e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13777.1 - 1.6e-11 44.0 0.0 2.3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK13777.1 - 4.4e-09 36.0 0.0 7.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KKK13777.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 B12D PF06522.6 KKK13778.1 - 7.7e-07 28.7 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit WD40 PF00400.27 KKK13779.1 - 3.4e-18 64.7 12.4 0.00016 21.4 0.0 7.3 6 1 1 7 7 7 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KKK13779.1 - 0.0012 18.3 0.0 1.2 8.6 0.0 4.7 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.2 KKK13779.1 - 0.0071 16.1 0.1 0.056 13.1 0.1 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 DUF946 PF06101.6 KKK13795.1 - 2.7e-12 45.4 2.0 2.7e-12 45.4 0.4 1.7 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) TFIIIC_sub6 PF10419.4 KKK13796.1 - 1.3e-16 59.7 0.1 2.6e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 TFIIIC subunit HECT PF00632.20 KKK13797.1 - 7.3e-93 311.1 0.0 1.1e-92 310.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KKK13797.1 - 2.5e-31 107.1 26.1 6e-11 42.0 3.0 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.25 KKK13797.1 - 6.7e-17 61.1 0.0 1.7e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 KKK13798.1 - 1.5e-16 59.7 0.0 2.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13798.1 - 1.9e-14 53.4 0.2 4.1e-14 52.3 0.0 1.7 2 0 0 2 2 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK13798.1 - 8.8e-06 25.4 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CASP_C PF08172.7 KKK13798.1 - 0.015 14.3 0.1 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal DUF904 PF06005.7 KKK13798.1 - 0.03 14.6 4.5 0.06 13.6 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 KKK13798.1 - 0.034 12.0 0.5 0.036 11.9 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KKK13798.1 - 0.035 13.6 3.0 0.042 13.4 2.1 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KKK13798.1 - 0.046 12.7 3.0 0.05 12.6 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Nup35_RRM_2 PF14605.1 KKK13798.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DivIC PF04977.10 KKK13798.1 - 0.1 12.1 5.7 0.17 11.3 3.9 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF724 PF05266.9 KKK13798.1 - 0.12 11.9 3.5 0.14 11.7 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlaC_arch PF05377.6 KKK13798.1 - 0.24 11.2 1.6 0.41 10.5 1.1 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 KKK13798.1 - 1.4 7.7 3.8 1.8 7.4 2.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4337 PF14235.1 KKK13798.1 - 3.5 7.4 5.9 4.9 6.9 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Metallophos_2 PF12850.2 KKK13799.1 - 3.2e-14 53.0 0.0 4.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.14 KKK13800.1 - 8.4e-28 97.1 0.0 1.1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KKK13800.1 - 0.00033 20.4 0.2 0.00082 19.2 0.0 1.7 2 0 0 2 2 2 1 B12 binding domain DDE_Tnp_1_4 PF13701.1 KKK13800.1 - 0.21 9.7 0.0 0.31 9.1 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 Sugar_tr PF00083.19 KKK13841.1 - 1.8e-75 254.2 23.5 3.7e-66 223.5 7.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK13841.1 - 1.7e-22 79.6 19.9 5e-22 78.0 13.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Alkyl_sulf_C PF14864.1 KKK13866.1 - 0.012 15.5 0.6 0.029 14.3 0.1 1.9 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal Reo_sigmaC PF04582.7 KKK13866.1 - 0.31 10.1 16.3 0.32 10.1 0.6 3.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein ERM PF00769.14 KKK13866.1 - 0.95 8.9 57.8 0.11 12.0 13.4 2.5 2 1 1 3 3 3 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 KKK13866.1 - 1.5 7.1 40.6 0.23 9.8 16.9 2.3 1 1 1 2 2 2 0 AAA domain Filament PF00038.16 KKK13866.1 - 3.2 7.1 50.0 3.6e+02 0.4 34.7 2.5 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.6 KKK13866.1 - 4.9 5.7 48.0 1.2 7.7 11.0 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein GAS PF13851.1 KKK13866.1 - 8.4 5.5 51.0 17 4.5 17.4 3.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Ribosomal_S4e PF00900.15 KKK13867.1 - 7e-33 112.1 0.2 1.3e-32 111.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KKK13867.1 - 5.6e-18 64.4 4.7 1.2e-17 63.4 3.3 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KKK13867.1 - 4.6e-06 25.9 0.0 8.4e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KKK13867.1 - 0.00034 20.2 3.7 0.00034 20.2 2.5 3.0 3 0 0 3 3 3 1 KOW motif RasGEF PF00617.14 KKK13868.1 - 0.013 15.1 0.0 0.22 11.2 0.0 2.6 2 1 1 3 3 3 0 RasGEF domain FAD-oxidase_C PF02913.14 KKK13869.1 - 9.4e-61 205.2 0.0 1.3e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KKK13869.1 - 1.5e-35 121.6 0.0 2.8e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 KKK13869.1 - 0.1 11.0 0.1 0.27 9.6 0.1 1.6 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Semialdhyde_dhC PF02774.13 KKK13870.1 - 2.8e-32 112.0 0.0 3.8e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KKK13870.1 - 2.8e-30 105.1 0.0 5.8e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KKK13870.1 - 0.022 15.2 0.0 0.061 13.8 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KKK13870.1 - 0.047 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 KKK13870.1 - 0.094 13.2 0.0 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RdRP PF05183.7 KKK13871.1 - 1.2e-181 605.3 0.0 1.9e-181 604.7 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 KKK13871.1 - 0.0092 15.5 0.0 0.028 14.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Slu7 PF11708.3 KKK13872.1 - 4.1e-81 272.2 17.4 4.1e-81 272.2 12.1 1.6 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KKK13872.1 - 0.014 15.0 0.8 0.034 13.8 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B PF00136.16 KKK13873.1 - 1.2e-96 324.3 0.0 1.7e-96 323.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KKK13873.1 - 5.2e-20 71.5 0.3 1.7e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KKK13873.1 - 1e-17 63.8 7.5 2.7e-17 62.5 5.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Peptidase_C65 PF10275.4 KKK13874.1 - 2.1e-63 213.9 0.0 2.5e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Ribosomal_L37e PF01907.14 KKK13875.1 - 9.2e-14 50.9 1.9 1.6e-13 50.1 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e zf-HYPF PF07503.7 KKK13875.1 - 0.11 11.8 0.5 0.11 11.8 0.3 1.6 2 0 0 2 2 2 0 HypF finger DUF2348 PF09807.4 KKK13876.1 - 2.3e-08 33.4 0.0 0.00041 19.5 0.0 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) Fungal_trans PF04082.13 KKK13877.1 - 1.9e-30 105.5 0.1 2.9e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13877.1 - 7.4e-10 38.5 14.0 1.2e-09 37.8 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KKK13877.1 - 4.2e-05 23.3 0.1 0.0001 22.1 0.1 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain Mur_ligase_M PF08245.7 KKK13907.1 - 1.1e-06 28.8 0.5 2.2e-06 27.8 0.3 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Ribonuc_red_lgC PF02867.10 KKK13908.1 - 3.2e-200 666.2 0.0 3.1e-139 465.0 0.0 2.4 2 1 1 3 3 3 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KKK13908.1 - 3.4e-24 84.4 0.0 7.8e-24 83.2 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KKK13908.1 - 7.1e-17 61.6 0.1 2.3e-16 59.9 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain Mucin PF01456.12 KKK13909.1 - 0.05 13.3 19.7 0.075 12.8 13.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PAP1 PF08601.5 KKK13909.1 - 0.16 11.6 8.0 0.17 11.5 5.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 CytochromB561_N PF09786.4 KKK13909.1 - 0.17 10.2 6.2 0.19 10.1 4.3 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DNA_pol_viral_N PF00242.12 KKK13909.1 - 0.79 8.6 5.4 0.89 8.5 3.7 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Sporozoite_P67 PF05642.6 KKK13909.1 - 4.9 4.8 13.6 5.6 4.7 9.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA_17 PF13207.1 KKK13910.1 - 0.0026 18.5 0.3 0.017 15.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KKK13910.1 - 0.0055 16.9 0.2 0.098 12.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KKK13910.1 - 0.062 12.2 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 KKK13910.1 - 0.1 12.4 0.1 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KKK13910.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Shisa PF13908.1 KKK13911.1 - 0.02 15.0 1.5 0.023 14.8 1.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SR-25 PF10500.4 KKK13911.1 - 0.031 13.7 7.1 0.037 13.5 4.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.2 KKK13911.1 - 0.057 12.9 0.2 0.064 12.7 0.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Apt1 PF10351.4 KKK13911.1 - 0.085 11.7 0.6 0.098 11.5 0.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Phage_tail_S PF05069.8 KKK13911.1 - 0.18 11.5 3.8 0.21 11.3 2.6 1.2 1 0 0 1 1 1 0 Phage virion morphogenesis family DUF2615 PF11027.3 KKK13911.1 - 0.18 11.7 0.8 0.2 11.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) WBP-1 PF11669.3 KKK13911.1 - 0.32 11.1 4.5 0.8 9.8 0.0 2.1 1 1 1 2 2 2 0 WW domain-binding protein 1 MSA-2c PF12238.3 KKK13911.1 - 1.2 8.7 3.5 1.5 8.4 2.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c ABC1 PF03109.11 KKK13912.1 - 1.8e-32 111.8 0.0 3.3e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KKK13912.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KKK13913.1 - 1.8e-70 237.1 0.0 5.4e-70 235.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13913.1 - 1.4e-50 171.7 0.0 2.9e-50 170.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13913.1 - 0.0026 16.7 0.0 0.013 14.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Fungal_trans PF04082.13 KKK13914.1 - 2.8e-30 105.0 0.4 5.2e-30 104.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Adap_comp_sub PF00928.16 KKK13915.1 - 1.2e-17 63.8 0.0 1.9e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KKK13915.1 - 0.00018 21.2 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 KKK13915.1 - 0.0044 17.1 0.4 0.0087 16.1 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) Mg_trans_NIPA PF05653.9 KKK13916.1 - 1.1e-93 313.5 14.5 5.1e-90 301.4 7.1 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 KKK13916.1 - 1.7e-05 24.8 4.6 1.7e-05 24.8 3.2 3.3 3 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 KKK13916.1 - 3.4e-05 23.9 4.2 3.4e-05 23.9 2.9 3.6 2 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF2937 PF11157.3 KKK13916.1 - 0.0057 15.9 1.1 0.011 15.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2937) DUF2420 PF10336.4 KKK13917.1 - 5.9e-11 41.9 0.7 1e-10 41.1 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) DUF4661 PF15576.1 KKK13917.1 - 3.4 7.2 7.6 11 5.5 5.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) HEAT PF02985.17 KKK13918.1 - 2.7e-27 92.3 17.0 7.9e-06 25.5 0.0 11.9 13 0 0 13 13 13 6 HEAT repeat HEAT_EZ PF13513.1 KKK13918.1 - 1.8e-26 91.8 13.2 8.1e-13 48.4 0.0 11.5 7 2 6 13 13 13 3 HEAT-like repeat HEAT_2 PF13646.1 KKK13918.1 - 7.1e-22 77.4 3.8 1.7e-07 31.3 0.0 8.5 3 3 5 8 8 8 5 HEAT repeats Cnd1 PF12717.2 KKK13918.1 - 5.3e-09 36.1 1.0 0.02 14.7 0.0 6.1 4 3 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KKK13918.1 - 6.8e-08 32.8 0.0 0.15 12.4 0.0 6.3 4 3 4 8 8 8 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KKK13918.1 - 1.6e-07 30.0 0.4 0.00023 19.6 0.0 3.6 3 0 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 KKK13918.1 - 2.7e-06 26.8 0.4 27 4.0 0.0 6.7 5 2 2 7 7 7 0 CLASP N terminal Arm PF00514.18 KKK13918.1 - 2.2e-05 24.1 3.4 0.23 11.3 0.0 5.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 KKK13918.1 - 9.7e-05 21.2 5.2 0.071 11.8 0.0 4.7 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal Xpo1 PF08389.7 KKK13918.1 - 0.00013 21.9 0.9 2.9 7.7 0.0 4.9 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 KKK13918.1 - 0.0014 18.5 2.0 0.2 11.5 0.0 4.7 4 1 1 5 5 5 1 Importin-beta N-terminal domain HEAT_PBS PF03130.11 KKK13918.1 - 0.0047 17.2 2.0 12 6.7 0.0 5.3 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Cohesin_HEAT PF12765.2 KKK13918.1 - 0.026 14.4 0.1 11 6.1 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion RIX1 PF08167.7 KKK13918.1 - 0.09 12.4 0.1 7.9 6.1 0.0 3.9 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis DUF3437 PF11919.3 KKK13918.1 - 0.12 12.1 0.0 0.48 10.1 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) DUF2741 PF10890.3 KKK13918.1 - 0.14 12.3 0.0 0.82 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2741) DUF1708 PF08101.6 KKK13918.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Syja_N PF02383.13 KKK13919.1 - 4.5e-99 331.2 0.0 6.9e-99 330.6 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KKK13919.1 - 1.5e-38 130.6 0.0 3.1e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase OMPdecase PF00215.19 KKK13920.1 - 4.5e-10 39.3 0.0 9e-07 28.5 0.0 2.4 2 1 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family TMF_DNA_bd PF12329.3 KKK13922.1 - 0.035 13.9 3.5 0.071 12.9 2.4 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 KKK13922.1 - 0.3 9.7 2.9 0.48 9.0 2.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein RRM_1 PF00076.17 KKK13923.1 - 1.5e-41 139.8 0.8 1.4e-19 69.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13923.1 - 9.8e-32 108.7 0.1 2e-17 62.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KKK13923.1 - 9.2e-30 102.7 0.2 2.2e-29 101.5 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KKK13923.1 - 1.9e-20 72.4 0.0 2.4e-08 33.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KKK13923.1 - 0.0056 16.5 0.0 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif MIP-T3 PF10243.4 KKK13923.1 - 2.1 6.7 21.6 3.4 6.0 15.0 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Cyt-b5 PF00173.23 KKK13924.1 - 4.3e-19 68.0 0.2 2.5e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KKK13924.1 - 1.4e-09 38.2 20.2 6e-09 36.3 13.6 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 KKK13924.1 - 0.063 12.9 2.2 0.16 11.6 0.4 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Anth_synt_I_N PF04715.8 KKK13924.1 - 0.087 12.8 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region GPI-anchored PF10342.4 KKK13925.1 - 5e-21 74.9 2.4 5e-21 74.9 1.7 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin PF01456.12 KKK13925.1 - 0.33 10.7 34.4 0.11 12.3 21.7 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Macoilin PF09726.4 KKK13925.1 - 0.38 8.9 17.9 0.41 8.8 12.4 1.0 1 0 0 1 1 1 0 Transmembrane protein CCDC84 PF14968.1 KKK13925.1 - 1 8.7 5.7 1.3 8.4 3.9 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Atrophin-1 PF03154.10 KKK13925.1 - 2.6 6.0 14.1 2.5 6.1 9.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF572 PF04502.8 KKK13925.1 - 4.1 6.5 6.6 4.9 6.2 4.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1005 PF06219.7 KKK13925.1 - 4.6 5.7 13.9 7.8 5.0 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) GHMP_kinases_N PF00288.21 KKK13926.1 - 2.1e-19 69.3 0.1 8.4e-19 67.4 0.1 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KKK13926.1 - 5.5e-07 29.7 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KKK13926.1 - 0.0047 16.1 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Fungal_trans_2 PF11951.3 KKK13927.1 - 1.3e-28 99.6 0.1 6.4e-18 64.5 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13927.1 - 3.9e-09 36.2 7.9 6.8e-09 35.5 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPTA PF01239.17 KKK13928.1 - 2.2e-38 127.9 20.7 2.6e-09 36.0 0.5 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.1 KKK13928.1 - 0.00063 20.0 0.3 0.0071 16.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK13928.1 - 0.027 15.1 0.0 0.42 11.3 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK13928.1 - 0.048 14.3 0.2 1 10.2 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KKK13928.1 - 0.18 11.4 1.8 0.56 9.8 0.3 2.5 3 0 0 3 3 3 0 TPR repeat PALP PF00291.20 KKK13929.1 - 8e-49 166.5 0.6 2.8e-48 164.7 0.1 1.9 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme DUF3446 PF11928.3 KKK13929.1 - 0.48 10.6 10.3 0.039 14.1 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) tRNA-synt_1g PF09334.6 KKK13930.1 - 8.3e-112 373.6 0.0 2.1e-111 372.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KKK13930.1 - 4.6e-23 81.0 0.1 1.1e-10 40.1 0.0 3.7 1 1 3 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KKK13930.1 - 5.4e-11 42.1 0.0 0.00025 20.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 KKK13930.1 - 1e-05 25.3 0.0 2.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA HTH_AraC PF00165.18 KKK13930.1 - 0.1 12.4 0.1 1.4 8.8 0.0 2.5 1 1 1 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family NTF2 PF02136.15 KKK13931.1 - 0.00042 20.6 0.4 0.00095 19.5 0.2 1.5 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KKK13931.1 - 0.0012 18.5 0.1 0.0057 16.4 0.1 1.8 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 Ish1 PF10281.4 KKK13932.1 - 0.00011 22.2 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF1470 PF07336.6 KKK13932.1 - 0.00024 21.4 1.5 0.00032 21.0 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1470) SAM_2 PF07647.12 KKK13932.1 - 0.074 12.9 0.1 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4129 PF13559.1 KKK13932.1 - 0.096 12.6 1.3 0.16 11.9 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) HTH_32 PF13565.1 KKK13932.1 - 0.37 11.6 2.6 0.46 11.3 0.8 1.9 1 1 1 2 2 2 0 Homeodomain-like domain Ribosomal_L38e PF01781.13 KKK13933.1 - 5e-32 109.4 1.8 6e-32 109.2 1.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Glyco_hydro_61 PF03443.9 KKK13934.1 - 2.3e-81 272.7 0.4 2.6e-81 272.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HIG_1_N PF04588.8 KKK13936.1 - 5.1e-06 26.1 4.2 1.1e-05 25.0 2.9 1.6 1 1 0 1 1 1 1 Hypoxia induced protein conserved region CcmD PF04995.9 KKK13936.1 - 0.047 13.4 1.2 0.17 11.6 0.8 2.0 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PTR2 PF00854.16 KKK13937.1 - 9.9e-43 146.3 15.8 9.8e-23 80.5 4.7 2.2 2 0 0 2 2 2 2 POT family MFS_1 PF07690.11 KKK13937.1 - 0.00011 21.0 24.3 0.00011 21.0 16.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.15 KKK13937.1 - 2.3 7.4 6.0 2.7 7.2 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function DUF21 NmrA PF05368.8 KKK13938.1 - 4.3e-31 107.9 0.0 5.6e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK13938.1 - 7.8e-10 39.0 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK13938.1 - 0.0013 18.2 0.0 0.022 14.2 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK13938.1 - 0.0078 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KKK13938.1 - 0.0088 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KKK13938.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein LtrA PF06772.6 KKK13945.1 - 8.8e-14 51.1 27.3 2.1e-12 46.6 12.9 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) NTR2 PF15458.1 KKK13946.1 - 8e-81 271.0 24.7 1.1e-80 270.5 17.1 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 PX PF00787.19 KKK13947.1 - 2.8e-19 68.9 0.0 4.1e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 PX domain CDP-OH_P_transf PF01066.16 KKK13948.1 - 4.2e-18 65.5 1.0 4.2e-18 65.5 0.7 2.4 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Peptidase_M1 PF01433.15 KKK13949.1 - 2.8e-08 33.2 0.0 0.017 14.2 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 LSM PF01423.17 KKK13950.1 - 7.4e-20 70.2 0.3 8.4e-20 70.1 0.2 1.0 1 0 0 1 1 1 1 LSM domain RPN7 PF10602.4 KKK13951.1 - 1.1e-56 191.0 0.1 2.1e-56 190.1 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KKK13951.1 - 8.3e-11 42.1 0.3 3.6e-10 40.0 0.1 2.2 2 0 0 2 2 2 1 PCI domain Glycophorin_A PF01102.13 KKK13952.1 - 0.17 11.6 1.1 0.26 11.0 0.7 1.7 1 1 0 1 1 1 0 Glycophorin A ELFV_dehydrog PF00208.16 KKK13996.1 - 2.4e-84 282.7 1.5 3e-84 282.4 1.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KKK13996.1 - 5.3e-48 161.9 0.0 9.5e-48 161.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF1019 PF06254.6 KKK14002.1 - 0.026 14.6 0.1 0.052 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) TPR_11 PF13414.1 KKK14003.1 - 1.7e-09 37.2 2.6 8.3e-07 28.5 0.2 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KKK14003.1 - 3.2e-06 26.6 2.5 0.018 14.9 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK14003.1 - 4.4e-06 26.0 1.1 0.054 13.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KKK14003.1 - 0.021 15.5 0.3 0.021 15.5 0.2 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK14003.1 - 0.1 12.4 1.6 11 6.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KKK14003.1 - 0.11 12.7 0.3 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat peroxidase PF00141.18 KKK14005.1 - 1.7e-47 161.8 0.0 2.4e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Ribosomal_S13 PF00416.17 KKK14006.1 - 1.5e-12 47.8 0.1 1.7e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.1 KKK14006.1 - 0.046 13.7 0.0 0.046 13.7 0.0 1.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif Actin PF00022.14 KKK14007.1 - 6.3e-144 479.2 0.0 7.1e-144 479.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KKK14007.1 - 0.0026 16.4 0.0 5.3 5.5 0.0 3.0 3 0 0 3 3 3 3 MreB/Mbl protein WD40 PF00400.27 KKK14017.1 - 4.9e-22 76.9 7.0 1.8e-05 24.3 0.4 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat SGL PF08450.7 KKK14017.1 - 0.011 15.1 0.0 0.14 11.4 0.0 2.1 1 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Rib_5-P_isom_A PF06026.9 KKK14018.1 - 2e-38 131.3 0.0 3.3e-34 117.6 0.0 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KKK14018.1 - 0.0019 17.8 0.1 1.1 8.8 0.0 2.2 1 1 0 2 2 2 2 DeoR C terminal sensor domain ThiF PF00899.16 KKK14019.1 - 1.3e-08 34.7 0.0 3.8e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 ThiF family RuvA_C PF07499.8 KKK14019.1 - 0.092 12.9 0.4 0.47 10.6 0.0 2.4 3 0 0 3 3 3 0 RuvA, C-terminal domain RNase_P_Rpp14 PF01900.14 KKK14020.1 - 7.4e-38 128.7 0.0 9.5e-38 128.4 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.12 KKK14021.1 - 1.1e-73 247.7 0.0 1.3e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KKK14021.1 - 0.00094 18.0 0.0 0.002 16.9 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 KKK14021.1 - 0.001 19.9 0.2 0.001 19.9 0.1 2.6 2 2 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KKK14021.1 - 0.0016 17.9 0.3 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain CbiA PF01656.18 KKK14021.1 - 0.0029 17.0 0.0 0.0063 15.9 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 KKK14021.1 - 0.0041 17.0 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KKK14021.1 - 0.0095 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK14021.1 - 0.078 12.0 0.4 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin MipZ PF09140.6 KKK14021.1 - 0.098 11.7 0.1 0.91 8.5 0.0 2.3 2 2 0 2 2 2 0 ATPase MipZ CDC45 PF02724.9 KKK14021.1 - 0.1 10.6 2.8 0.13 10.2 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Bd3614_N PF14442.1 KKK14021.1 - 0.12 12.3 3.9 0.18 11.7 2.7 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal AAA_29 PF13555.1 KKK14021.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KKK14021.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KKK14021.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Cpn10 PF00166.16 KKK14022.1 - 3.8e-18 65.2 0.1 2.5e-15 56.1 0.0 2.0 1 1 1 2 2 2 2 Chaperonin 10 Kd subunit P22_Cro PF14549.1 KKK14022.1 - 0.13 11.9 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro XAP5 PF04921.9 KKK14023.1 - 5e-83 278.3 1.3 3.8e-82 275.4 0.0 2.4 3 0 0 3 3 3 1 XAP5, circadian clock regulator FTCD_C PF04961.7 KKK14023.1 - 0.08 12.3 0.9 0.17 11.2 0.6 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase V_ATPase_I PF01496.14 KKK14023.1 - 0.18 9.6 2.5 0.32 8.7 1.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lge1 PF11488.3 KKK14023.1 - 0.18 11.9 4.1 0.25 11.5 1.6 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 KKK14023.1 - 0.32 10.5 1.7 0.88 9.1 1.2 1.7 1 0 0 1 1 1 0 IncA protein DUF948 PF06103.6 KKK14023.1 - 0.34 10.7 2.5 0.67 9.8 1.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 KKK14023.1 - 0.43 10.7 6.7 0.86 9.7 4.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Fip1 PF05182.8 KKK14024.1 - 7.5e-21 73.1 2.1 1.2e-20 72.4 1.4 1.3 1 0 0 1 1 1 1 Fip1 motif Ribosomal_60s PF00428.14 KKK14024.1 - 0.17 12.3 6.0 0.85 10.0 3.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein CoA_binding PF02629.14 KKK14025.1 - 3.8e-18 65.7 0.0 1.4e-17 64.0 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KKK14025.1 - 3.1e-15 56.1 0.1 5.4e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Citrate_synt PF00285.16 KKK14025.1 - 9.7e-15 54.1 0.1 3.2e-12 45.8 0.1 2.9 1 1 1 2 2 2 2 Citrate synthase Succ_CoA_lig PF13607.1 KKK14025.1 - 1.3e-06 28.0 0.0 8.2e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 KKK14026.1 - 5.1e-08 32.5 0.0 7.6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PX PF00787.19 KKK14029.1 - 1.6e-18 66.5 3.3 3.7e-18 65.3 0.0 2.9 3 1 0 3 3 3 1 PX domain Vps5 PF09325.5 KKK14029.1 - 4.8e-10 39.0 9.8 9.1e-06 25.0 1.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.12 KKK14029.1 - 0.0082 15.9 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase C10 family Dicty_REP PF05086.7 KKK14029.1 - 0.14 9.9 1.2 0.21 9.2 0.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 KKK14030.1 - 1.5e-48 165.2 0.0 2.4e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14030.1 - 1.7e-25 89.5 0.0 2.8e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK14030.1 - 0.058 12.3 0.0 0.2 10.6 0.0 1.9 1 1 0 1 1 1 0 Kinase-like DUF2428 PF10350.4 KKK14031.1 - 3.5e-80 268.7 0.0 7.6e-80 267.6 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.1 KKK14031.1 - 2.9e-05 24.2 3.3 0.57 10.5 0.1 4.3 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 KKK14031.1 - 6.1e-05 22.7 9.3 2.6 8.3 0.1 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KKK14031.1 - 0.49 10.9 10.1 1 9.9 0.1 4.8 4 0 0 4 4 4 0 HEAT-like repeat Tim17 PF02466.14 KKK14032.1 - 3.9e-26 91.5 5.4 5e-26 91.2 3.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_43 PF04616.9 KKK14033.1 - 5.3e-34 117.5 0.0 8.3e-34 116.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 ING PF12998.2 KKK14036.1 - 0.069 13.4 0.4 2.7 8.3 0.1 2.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding RadC PF04002.10 KKK14036.1 - 0.13 11.9 0.8 0.17 11.5 0.4 1.5 1 1 0 1 1 1 0 RadC-like JAB domain TBD PF12845.2 KKK14036.1 - 0.14 11.7 0.3 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 TBD domain Phosphoesterase PF04185.9 KKK14038.1 - 8.9e-36 123.8 5.1 2.9e-35 122.2 3.5 1.7 1 1 0 1 1 1 1 Phosphoesterase family Mgm101p PF06420.7 KKK14047.1 - 1.5e-89 297.7 0.0 1.9e-89 297.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DUF1602 PF07673.9 KKK14047.1 - 0.024 14.0 0.0 0.062 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1602) 4HBT_3 PF13622.1 KKK14047.1 - 0.63 9.7 5.0 0.93 9.1 3.5 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily CHCH PF06747.8 KKK14048.1 - 5.3e-07 29.3 7.4 7.4e-07 28.9 5.1 1.2 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 KKK14048.1 - 0.013 15.4 2.0 0.018 15.0 1.4 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KKK14048.1 - 0.016 14.9 5.6 0.032 14.0 3.9 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Toxin_25 PF08095.6 KKK14048.1 - 0.017 14.8 0.6 0.017 14.8 0.4 2.1 2 1 0 2 2 2 0 Hefutoxin family Pet191_N PF10203.4 KKK14048.1 - 0.26 11.3 3.4 0.37 10.8 2.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Ndufs5 PF10200.4 KKK14048.1 - 0.43 10.6 3.4 1.6 8.7 2.3 1.7 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Zn_clus PF00172.13 KKK14049.1 - 7.4e-08 32.1 11.8 1.5e-07 31.2 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MS_channel PF00924.13 KKK14050.1 - 6.3e-21 74.6 1.2 1.1e-20 73.9 0.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KKK14050.1 - 5.4e-05 22.2 0.4 0.00012 21.0 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KKK14050.1 - 0.0004 20.0 0.1 0.0023 17.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KKK14050.1 - 0.0013 18.8 0.2 0.0036 17.3 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KKK14050.1 - 0.13 11.6 0.1 0.41 10.0 0.0 1.8 1 0 0 1 1 1 0 EF hand NRDE PF05742.7 KKK14051.1 - 1.6e-43 148.9 0.0 1.9e-40 138.9 0.0 2.0 2 0 0 2 2 2 2 NRDE protein TB2_DP1_HVA22 PF03134.14 KKK14052.1 - 2.6e-13 49.5 2.8 4.5e-13 48.7 1.9 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family BPL_N PF09825.4 KKK14053.1 - 2.4e-121 405.0 0.0 3e-121 404.6 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KKK14053.1 - 5.5e-21 74.8 0.0 1.2e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 KKK14053.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain p450 PF00067.17 KKK14054.1 - 9.2e-46 156.3 0.0 1.3e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1768 PF08719.6 KKK14055.1 - 4.6e-37 127.1 0.0 6.6e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ADH_zinc_N PF00107.21 KKK14056.1 - 2.3e-10 40.0 0.0 4.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK14056.1 - 9.8e-08 31.7 0.0 6.9e-07 29.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KKK14056.1 - 0.023 15.5 0.0 0.057 14.3 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase zf-RING_2 PF13639.1 KKK14057.1 - 2.8e-15 55.8 5.6 4.8e-15 55.1 3.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KKK14057.1 - 5.7e-08 32.7 2.5 1e-07 31.9 1.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KKK14057.1 - 1.1e-07 31.3 3.6 1.8e-07 30.7 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK14057.1 - 6.2e-07 29.3 5.3 1e-06 28.6 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK14057.1 - 3.4e-06 26.6 2.7 5.7e-06 25.9 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK14057.1 - 7.6e-06 25.5 2.2 1.2e-05 24.8 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KKK14057.1 - 0.0013 18.4 2.8 0.0028 17.4 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KKK14057.1 - 0.0019 17.7 3.5 0.0033 16.9 2.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KKK14057.1 - 0.075 13.0 2.9 0.13 12.3 2.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KKK14057.1 - 0.49 10.3 5.9 0.95 9.3 4.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KKK14057.1 - 0.68 9.9 4.5 4.7 7.2 3.1 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KKK14057.1 - 3.3 7.4 5.0 15 5.3 3.5 2.0 1 1 1 2 2 2 0 PHD-finger Aminotran_1_2 PF00155.16 KKK14067.1 - 1.6e-72 244.4 0.0 1.8e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_3 PF07859.8 KKK14068.1 - 3e-10 40.0 0.2 7.1e-05 22.4 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Pectate_lyase_3 PF12708.2 KKK14068.1 - 0.11 12.5 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Pectate lyase superfamily protein Lyase_1 PF00206.15 KKK14069.1 - 3.7e-115 384.3 0.0 4.9e-115 384.0 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KKK14069.1 - 3.6e-22 78.1 0.0 1.1e-21 76.6 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus Acetyltransf_7 PF13508.1 KKK14070.1 - 1e-11 44.7 0.2 2.2e-11 43.7 0.2 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK14070.1 - 1e-09 38.3 0.1 1.6e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KKK14070.1 - 0.0041 17.2 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK14070.1 - 0.006 16.7 0.0 0.0073 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK14070.1 - 0.08 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S30 PF04758.9 KKK14071.1 - 1.7e-12 46.8 1.4 2.2e-12 46.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 Ecl1 PF12855.2 KKK14072.1 - 1.1e-07 31.0 0.6 2.5e-07 29.8 0.4 1.7 1 1 0 1 1 1 1 Life-span regulatory factor MoCF_biosynth PF00994.19 KKK14073.1 - 3.8e-37 126.8 0.0 6.7e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain AMPKBI PF04739.10 KKK14076.1 - 1.8e-29 101.5 0.1 4.8e-29 100.2 0.1 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain EPL1 PF10513.4 KKK14078.1 - 2.7e-31 108.9 0.7 2.7e-31 108.9 0.5 3.3 2 1 1 3 3 3 1 Enhancer of polycomb-like SET PF00856.23 KKK14079.1 - 1.8e-16 60.8 0.0 1.1e-14 55.0 0.0 2.7 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 KKK14079.1 - 9.9e-06 25.4 4.0 4.2e-05 23.4 2.8 2.0 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding LEM PF03020.10 KKK14079.1 - 0.00058 19.2 0.1 0.0023 17.3 0.1 2.0 1 0 0 1 1 1 1 LEM domain Peptidase_M22 PF00814.20 KKK14080.1 - 2.4e-84 282.9 0.0 2.8e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family EF-hand_1 PF00036.27 KKK14081.1 - 1.4e-25 86.5 19.0 1e-07 30.7 0.5 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KKK14081.1 - 1.1e-22 79.9 4.5 8e-12 45.1 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KKK14081.1 - 9e-21 71.8 7.7 8.4e-06 25.2 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KKK14081.1 - 4.3e-18 63.7 14.1 9.8e-06 24.6 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KKK14081.1 - 2.7e-15 55.7 16.5 2.4e-05 23.8 0.6 4.4 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KKK14081.1 - 3.5e-07 30.2 0.0 0.00088 19.2 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KKK14081.1 - 0.00049 19.7 11.2 0.44 10.3 0.3 4.1 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KKK14081.1 - 0.014 15.3 0.1 0.75 9.7 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain Anthrax-tox_M PF09156.5 KKK14081.1 - 0.023 13.8 1.0 0.057 12.5 0.0 1.8 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain ATP-cone PF03477.11 KKK14081.1 - 0.1 13.0 0.3 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 ATP cone domain Pkinase PF00069.20 KKK14082.1 - 4.1e-26 91.6 0.0 5.8e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14082.1 - 1.5e-06 27.4 0.2 3.6e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_3 PF00933.16 KKK14083.1 - 1.6e-73 247.3 0.0 2.2e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK14083.1 - 5.5e-47 160.1 0.0 7.8e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK14083.1 - 3.8e-10 39.5 0.0 7.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans_2 PF11951.3 KKK14084.1 - 3.1e-13 49.1 0.1 1.5e-12 46.8 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14084.1 - 2.2e-06 27.4 12.9 2.2e-06 27.4 8.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.23 KKK14085.1 - 9e-17 61.1 0.1 2.1e-16 59.8 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KKK14085.1 - 5.7e-16 58.3 0.0 1.2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KKK14085.1 - 3.5e-05 22.5 0.1 6.4e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase fn3 PF00041.16 KKK14085.1 - 0.0043 17.1 2.0 0.0093 16.0 1.4 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Metallophos_2 PF12850.2 KKK14085.1 - 0.0091 15.8 0.1 0.023 14.5 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cupin_2 PF07883.6 KKK14085.1 - 0.067 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Cupin domain SIMPL PF04402.9 KKK14087.1 - 1.7e-25 90.1 0.0 2e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) MFS_1 PF07690.11 KKK14088.1 - 1.5e-25 89.7 51.6 2.1e-15 56.3 24.8 3.5 3 1 0 3 3 3 2 Major Facilitator Superfamily YvrJ PF12841.2 KKK14088.1 - 0.099 11.9 0.3 0.35 10.1 0.0 2.0 2 0 0 2 2 2 0 YvrJ protein family UNC-93 PF05978.11 KKK14088.1 - 0.23 10.9 10.2 5.5 6.4 0.4 3.6 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 DUF4077 PF13295.1 KKK14088.1 - 0.84 9.3 10.0 0.15 11.7 0.4 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4077) DUF3431 PF11913.3 KKK14089.1 - 2.9e-75 252.5 0.0 3.5e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF500 PF04366.7 KKK14090.1 - 5.9e-25 87.1 0.0 1.1e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Sox_C_TAD PF12067.3 KKK14090.1 - 0.17 12.0 3.8 0.3 11.2 2.6 1.3 1 0 0 1 1 1 0 Sox C-terminal transactivation domain Epimerase PF01370.16 KKK14091.1 - 1.4e-13 50.8 1.7 1.3e-12 47.7 1.2 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK14091.1 - 2.1e-07 30.1 0.1 0.00058 18.8 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KKK14091.1 - 1.3e-06 28.5 0.8 3.3e-06 27.2 0.3 1.8 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK14091.1 - 9.9e-05 21.1 0.0 0.0093 14.6 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KKK14091.1 - 0.00011 21.5 0.0 0.00024 20.4 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KKK14091.1 - 0.00079 19.3 0.3 0.0016 18.3 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KKK14091.1 - 0.025 13.4 0.2 0.15 10.9 0.0 1.9 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 KKK14091.1 - 0.11 12.1 0.4 0.46 10.1 0.1 1.8 1 1 1 2 2 2 0 KR domain Zn_clus PF00172.13 KKK14092.1 - 1.8e-08 34.1 11.8 3.8e-08 33.0 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK14092.1 - 2.1e-05 23.5 1.2 3.7e-05 22.7 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KKK14093.1 - 1.2e-32 113.0 47.1 1.8e-21 76.2 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK14093.1 - 3.5e-06 25.8 43.7 0.00014 20.6 11.6 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KKK14093.1 - 5.5e-05 22.8 9.5 0.0019 17.9 3.7 3.6 3 0 0 3 3 3 1 MFS_1 like family PARP PF00644.15 KKK14094.1 - 8.3e-38 129.8 0.0 5.1e-37 127.3 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KKK14094.1 - 2.6e-33 114.5 0.2 5.1e-33 113.5 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KKK14094.1 - 1.3e-08 34.6 0.8 2.6e-08 33.6 0.6 1.5 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 KKK14094.1 - 2.8e-08 33.7 0.0 7e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KKK14094.1 - 2.4e-06 27.3 0.2 4.9e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain Pyridoxal_deC PF00282.14 KKK14095.1 - 3.3e-106 354.8 0.0 4e-106 354.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KKK14095.1 - 0.0036 16.5 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Ank_2 PF12796.2 KKK14096.1 - 1.4e-54 182.3 1.2 5e-16 58.8 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KKK14096.1 - 2e-41 137.7 6.3 5.6e-09 35.3 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KKK14096.1 - 1.7e-39 133.4 2.2 7.9e-13 48.5 0.0 4.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK14096.1 - 6.4e-34 115.2 5.5 2.8e-08 33.7 0.0 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK14096.1 - 1.5e-30 102.1 0.9 3.4e-07 29.8 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat F-box-like PF12937.2 KKK14096.1 - 0.07 12.8 0.6 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 F-box-like FCD PF07729.7 KKK14096.1 - 0.13 12.5 2.4 3.1 8.1 0.1 2.4 2 1 0 2 2 2 0 FCD domain Fungal_trans PF04082.13 KKK14097.1 - 2.4e-13 49.5 0.0 4.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14097.1 - 0.12 12.3 6.7 0.22 11.4 4.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_C PF02752.17 KKK14098.1 - 5.2e-10 39.5 0.2 1.2e-09 38.3 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MFS_1 PF07690.11 KKK14099.1 - 3.1e-51 174.1 46.2 3.1e-51 174.1 32.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK14099.1 - 3.6e-21 75.0 22.8 5.4e-21 74.4 15.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK14099.1 - 4.8e-16 58.3 6.2 4.8e-16 58.3 4.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF500 PF04366.7 KKK14099.1 - 0.049 13.0 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF500) DUF543 PF04418.7 KKK14099.1 - 3.1 7.8 8.4 14 5.7 0.1 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF543) FAD_binding_2 PF00890.19 KKK14100.1 - 2.5e-62 211.0 0.6 2.9e-62 210.8 0.4 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK14100.1 - 3.2e-09 36.1 0.1 1.6e-08 33.8 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK14100.1 - 4.9e-07 29.8 0.0 4e-05 23.5 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK14100.1 - 8.2e-07 28.9 0.1 5e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK14100.1 - 2e-06 28.0 0.0 2e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK14100.1 - 4.4e-06 25.4 1.4 0.012 14.0 0.2 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 KKK14100.1 - 0.00013 20.9 3.6 0.019 13.8 0.2 2.9 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KKK14100.1 - 0.00051 19.2 0.6 0.001 18.2 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KKK14100.1 - 0.00065 18.8 0.5 0.0059 15.7 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 KKK14100.1 - 0.02 13.9 0.0 0.065 12.3 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KKK14100.1 - 0.034 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KKK14100.1 - 0.08 13.3 0.4 0.32 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK14100.1 - 0.1 11.4 0.4 0.28 10.0 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KKK14100.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.1 KKK14101.1 - 1.8e-15 57.9 0.1 4.3e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KKK14101.1 - 2.3e-12 46.5 0.2 4.2e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK14101.1 - 2.1e-05 24.2 0.0 0.00012 21.8 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KKK14101.1 - 0.004 17.1 0.3 0.009 16.0 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KKK14101.1 - 0.031 13.1 0.0 0.069 12.0 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain bZIP_1 PF00170.16 KKK14102.1 - 4.7e-06 26.4 0.6 8.4e-06 25.6 0.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 KKK14102.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain ATG16 PF08614.6 KKK14102.1 - 0.15 11.9 0.8 0.24 11.2 0.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FA_hydroxylase PF04116.8 KKK14103.1 - 6e-13 49.1 16.2 6e-13 49.1 11.2 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily PH_6 PF15406.1 KKK14104.1 - 5.7e-38 129.4 1.2 5.7e-38 129.4 0.8 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KKK14104.1 - 0.00011 22.3 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 KKK14104.1 - 0.37 10.3 1.7 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.20 KKK14118.1 - 1.2e-32 113.0 0.0 2.9e-32 111.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14118.1 - 1.1e-15 57.4 0.0 6.1e-15 55.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KKK14118.1 - 0.0012 17.7 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 KKK14118.1 - 0.003 17.3 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK14118.1 - 0.029 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 KKK14118.1 - 0.033 13.3 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 KKK14118.1 - 0.046 13.0 0.1 0.096 12.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family S1FA PF04689.8 KKK14118.1 - 0.13 12.1 0.1 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 DNA binding protein S1FA JmjC PF02373.17 KKK14125.1 - 3.9e-09 36.7 0.0 3.6e-08 33.6 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KKK14125.1 - 6.7e-09 35.6 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.24 KKK14125.1 - 1.9e-08 33.8 4.4 1.9e-08 33.8 3.1 2.7 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 KKK14125.1 - 0.0037 16.5 4.4 0.0053 16.0 1.7 2.4 2 0 0 2 2 2 1 PHD-finger Dickkopf_N PF04706.7 KKK14125.1 - 0.31 11.2 11.3 3.6 7.8 1.7 2.9 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.13 KKK14125.1 - 2.6 8.0 28.3 0.13 12.1 3.6 3.2 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 KKK14130.1 - 9.1e-51 172.6 43.1 2.4e-30 105.3 14.7 3.0 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KKK14130.1 - 3e-22 78.7 36.6 3e-22 78.7 25.4 2.2 1 1 0 1 1 1 1 Amino acid permease Nnf1 PF03980.9 KKK14130.1 - 0.22 11.5 0.2 0.4 10.6 0.1 1.3 1 0 0 1 1 1 0 Nnf1 CP_ATPgrasp_2 PF14403.1 KKK14131.1 - 5.7e-08 31.8 0.0 0.0021 16.8 0.0 2.2 2 0 0 2 2 2 2 Circularly permuted ATP-grasp type 2 TauD PF02668.11 KKK14132.1 - 3.2e-20 72.8 0.6 4.1e-20 72.5 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KKK14132.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.4 1 0 0 1 1 1 1 CsiD AMP-binding PF00501.23 KKK14133.1 - 0.017 13.5 0.0 0.023 13.0 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme ACOX PF01756.14 KKK14135.1 - 1.3e-36 125.7 0.0 3.6e-36 124.3 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KKK14135.1 - 1.2e-26 93.4 0.2 2.4e-26 92.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 KKK14135.1 - 8.4e-06 25.9 0.6 0.0026 17.8 0.4 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KKK14135.1 - 0.0082 15.6 1.4 1.5 8.3 0.2 3.2 2 1 1 3 3 3 2 Acyl-CoA dehydrogenase, middle domain DIOX_N PF14226.1 KKK14136.1 - 1.3e-27 96.6 0.1 2e-27 96.0 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK14136.1 - 1.9e-22 79.3 0.0 3.7e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 KKK14137.1 - 7.1e-77 258.8 0.0 7.8e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.1 KKK14138.1 - 1.5e-08 34.9 0.0 2.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK14138.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK14138.1 - 0.0019 17.8 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK14138.1 - 0.014 15.8 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 KKK14138.1 - 0.035 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Pox_MCEL PF03291.11 KKK14138.1 - 0.056 12.3 0.0 0.17 10.7 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme MFS_1 PF07690.11 KKK14139.1 - 3.2e-29 101.7 71.5 3.4e-22 78.6 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1279 PF06916.8 KKK14139.1 - 0.018 15.3 1.0 0.018 15.3 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Abhydrolase_3 PF07859.8 KKK14140.1 - 4.5e-46 157.0 0.0 5.7e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK14140.1 - 3.6e-10 39.1 1.6 1.1e-09 37.5 1.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KKK14140.1 - 0.18 10.3 0.0 0.28 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Glyco_hydro_43 PF04616.9 KKK14143.1 - 5e-60 203.0 2.8 6.8e-60 202.5 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3686 PF12458.3 KKK14143.1 - 0.08 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 ATPase involved in DNA repair Zn_clus PF00172.13 KKK14144.1 - 2.3e-07 30.6 6.2 2.3e-07 30.6 4.3 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 KKK14144.1 - 0.0092 15.3 1.4 0.021 14.1 1.0 1.6 1 0 0 1 1 1 1 Mitochondrial fission regulator EAP30 PF04157.11 KKK14144.1 - 0.036 13.2 0.6 0.063 12.4 0.4 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family CAP_N PF01213.14 KKK14144.1 - 0.55 9.4 5.5 0.2 10.9 1.5 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal AMP-binding PF00501.23 KKK14145.1 - 5.7e-87 291.7 0.0 7.5e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK14145.1 - 1e-13 52.0 0.0 2.7e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.14 KKK14146.1 - 3.2e-68 229.8 0.0 1.2e-54 185.2 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KKK14146.1 - 5.8e-08 32.2 0.0 9.1e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KKK14146.1 - 2.3e-07 29.8 0.0 5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V AMP-binding PF00501.23 KKK14147.1 - 2.5e-59 200.7 0.0 3.5e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KKK14147.1 - 4.1e-48 163.7 0.2 3.2e-29 101.7 0.0 2.8 3 1 0 3 3 3 2 Condensation domain PP-binding PF00550.20 KKK14147.1 - 2.7e-07 30.7 0.0 7e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK14147.1 - 0.00027 21.7 0.0 0.00078 20.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain E2 PF08199.6 KKK14147.1 - 0.21 11.2 0.2 0.56 9.8 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage E2-like protein Condensation PF00668.15 KKK14148.1 - 1.2e-34 119.6 1.1 2.5e-34 118.5 0.2 2.0 2 1 0 2 2 2 1 Condensation domain PP-binding PF00550.20 KKK14148.1 - 1.5e-13 50.7 0.6 8.1e-13 48.4 0.1 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Adap_comp_sub PF00928.16 KKK14149.1 - 1.3e-52 178.5 0.0 2.5e-43 148.0 0.0 2.3 2 1 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KKK14149.1 - 0.0001 22.0 0.4 0.0002 21.0 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NST1 PF13945.1 KKK14149.1 - 0.036 14.1 2.6 0.058 13.4 1.8 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator TFIIF_alpha PF05793.7 KKK14149.1 - 0.16 10.2 10.3 0.23 9.7 7.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FTCD_C PF04961.7 KKK14149.1 - 0.28 10.5 1.1 0.49 9.7 0.7 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Pol_alpha_B_N PF08418.5 KKK14149.1 - 0.65 9.4 10.4 1 8.8 7.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF605 PF04652.11 KKK14149.1 - 0.84 8.9 21.2 1.3 8.3 14.7 1.2 1 0 0 1 1 1 0 Vta1 like BTB_2 PF02214.17 KKK14150.1 - 2.5e-08 34.0 0.0 4.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KKK14150.1 - 3.4e-05 23.7 0.0 5.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF4588 PF15251.1 KKK14151.1 - 5.3 6.9 19.5 87 2.9 13.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) DUF4536 PF15055.1 KKK14152.1 - 0.00045 20.2 1.0 0.00045 20.2 0.7 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4536) MOZ_SAS PF01853.13 KKK14153.1 - 1.7e-79 265.4 0.0 2.4e-79 264.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KKK14153.1 - 0.00023 20.7 8.5 0.00023 20.7 5.9 2.1 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.15 KKK14153.1 - 0.092 12.2 2.1 0.21 11.1 1.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Zn-ribbon_8 PF09723.5 KKK14153.1 - 2.8 7.9 5.3 0.48 10.4 0.2 2.2 1 1 1 2 2 2 0 Zinc ribbon domain SNF2_N PF00176.18 KKK14154.1 - 9.9e-83 277.3 0.5 1.7e-82 276.6 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KKK14154.1 - 1.1e-45 154.1 2.8 1.7e-45 153.5 0.7 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 KKK14154.1 - 6.4e-36 123.1 0.8 6.4e-36 123.1 0.5 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KKK14154.1 - 2.1e-14 53.1 0.0 1.1e-13 50.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK14154.1 - 1.2e-08 35.0 0.0 5.7e-08 32.8 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KKK14154.1 - 8.4e-06 25.3 0.0 2.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KKK14154.1 - 0.023 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 KKK14154.1 - 0.026 14.4 1.0 0.074 12.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Acetyltransf_2 PF00797.12 KKK14155.1 - 1.7e-38 132.5 0.0 2.5e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase PetG PF02529.10 KKK14156.1 - 0.097 12.2 2.1 0.15 11.6 1.4 1.2 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Methyltransf_6 PF03737.10 KKK14158.1 - 2e-22 79.6 0.1 2.8e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Thiolase_N PF00108.18 KKK14159.1 - 3.5e-76 255.6 4.1 3.5e-76 255.6 2.9 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK14159.1 - 7.1e-44 148.1 0.3 1.8e-43 146.9 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain Trigger_N PF05697.8 KKK14159.1 - 0.085 12.6 0.1 0.39 10.5 0.1 2.0 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) NUC173 PF08161.7 KKK14160.1 - 1.3e-79 266.1 0.1 9.4e-79 263.3 0.0 2.4 3 0 0 3 3 3 1 NUC173 domain Stork_head PF10264.4 KKK14160.1 - 0.022 14.9 0.0 0.091 12.9 0.0 2.1 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain HEAT_2 PF13646.1 KKK14160.1 - 0.028 14.6 2.6 3.7 7.9 0.0 4.6 4 1 0 4 4 4 0 HEAT repeats HEAT PF02985.17 KKK14160.1 - 0.033 14.2 1.0 4.3 7.6 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat Menin PF05053.8 KKK14160.1 - 2.1 6.4 7.8 4.1 5.4 5.4 1.3 1 0 0 1 1 1 0 Menin Cation_efflux PF01545.16 KKK14161.1 - 3.1e-33 115.0 8.0 4e-33 114.7 5.6 1.1 1 0 0 1 1 1 1 Cation efflux family zf-rbx1 PF12678.2 KKK14163.1 - 3.5e-09 36.6 0.3 7.4e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KKK14163.1 - 7.1e-09 35.3 10.5 1.3e-07 31.2 7.3 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK14163.1 - 5.2e-07 29.2 0.6 9.1e-07 28.4 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK14163.1 - 1e-06 28.3 3.1 3.1e-06 26.7 2.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK14163.1 - 2.4e-06 27.0 5.4 9.2e-06 25.2 3.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK14163.1 - 2.3e-05 24.2 2.9 2.3e-05 24.2 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KKK14163.1 - 0.0067 16.2 1.2 0.016 15.0 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KKK14163.1 - 0.75 9.5 4.4 0.62 9.8 1.0 2.4 1 1 1 2 2 2 0 RING-type zinc-finger DUF3671 PF12420.3 KKK14163.1 - 1 9.3 2.4 18 5.3 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function FANCL_C PF11793.3 KKK14163.1 - 2.7 7.9 5.9 13 5.8 4.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3099 PF11298.3 KKK14163.1 - 4.1 7.2 5.9 3.2 7.5 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3099) COMPASS-Shg1 PF05205.7 KKK14164.1 - 2.4e-30 104.9 0.3 5.6e-30 103.7 0.2 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.13 KKK14165.1 - 5.7e-37 126.7 0.1 7e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E GDA1_CD39 PF01150.12 KKK14166.1 - 7.6e-92 308.0 0.0 9.9e-92 307.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.1 KKK14167.1 - 7.6e-35 119.5 6.3 7.6e-35 119.5 4.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) DUF2201_N PF13203.1 KKK14167.1 - 4.2 6.4 8.7 0.48 9.5 2.7 1.6 1 1 1 2 2 2 0 Putative metallopeptidase domain GTP_EFTU PF00009.22 KKK14168.1 - 6.4e-60 201.8 0.1 9e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KKK14168.1 - 3.1e-20 72.2 0.0 1.9e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KKK14168.1 - 1e-17 64.0 2.2 2.5e-17 62.7 1.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KKK14168.1 - 1.3e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KKK14168.1 - 0.0025 17.3 0.2 0.0062 16.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KKK14168.1 - 0.0045 17.4 0.0 0.0076 16.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KKK14168.1 - 0.09 12.2 0.3 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KKK14168.1 - 0.099 12.0 0.6 0.78 9.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IF3_C PF00707.17 KKK14169.1 - 7.2e-18 64.1 2.2 1.1e-17 63.5 1.5 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 KKK14169.1 - 1.8e-06 27.4 2.5 8.8e-06 25.2 0.5 2.4 1 1 2 3 3 3 1 Mitochondrial translation initiation factor IF3_N PF05198.11 KKK14169.1 - 0.00022 21.0 0.0 0.00058 19.7 0.0 1.7 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain ALO PF04030.9 KKK14169.1 - 0.098 12.2 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cyclase PF04199.8 KKK14170.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 KKK14170.1 - 0.0045 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) HMG_box_2 PF09011.5 KKK14170.1 - 0.14 12.5 0.2 0.31 11.4 0.1 1.6 2 0 0 2 2 2 0 HMG-box domain RHD3 PF05879.7 KKK14171.1 - 0 1082.3 0.0 0 1082.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KKK14171.1 - 2.8e-08 33.1 0.3 4.7e-08 32.4 0.2 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KKK14171.1 - 2.3e-06 27.5 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KKK14171.1 - 0.0001 22.2 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KKK14171.1 - 0.0012 18.8 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KKK14171.1 - 0.0022 18.4 0.0 0.0046 17.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein 4HBT_2 PF13279.1 KKK14172.1 - 1.7e-09 38.1 0.0 2.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily BRAP2 PF07576.7 KKK14191.1 - 9.4e-26 89.5 0.0 1.9e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KKK14191.1 - 4.2e-20 71.6 2.9 1.3e-19 70.0 2.0 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KKK14191.1 - 3.6e-09 36.2 9.9 3.6e-09 36.2 6.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KKK14191.1 - 0.00019 21.1 7.7 0.00019 21.1 5.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK14191.1 - 0.00099 18.7 8.8 0.00099 18.7 6.1 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK14191.1 - 0.001 19.0 9.7 0.001 19.0 6.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK14191.1 - 0.0015 18.1 6.1 0.0015 18.1 4.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KKK14191.1 - 0.0016 18.0 4.7 0.0059 16.2 1.8 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KKK14191.1 - 0.002 18.2 5.5 0.002 18.2 3.8 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KKK14191.1 - 0.013 15.2 3.5 0.013 15.2 2.4 2.1 2 0 0 2 2 1 0 zf-RING of BARD1-type protein TPR_MLP1_2 PF07926.7 KKK14191.1 - 0.025 14.3 9.7 0.045 13.4 6.7 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein EzrA PF06160.7 KKK14191.1 - 0.2 9.8 6.2 0.28 9.3 4.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Shugoshin_N PF07558.6 KKK14191.1 - 0.33 10.7 2.0 0.72 9.6 1.4 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CCDC155 PF14662.1 KKK14191.1 - 0.35 10.4 8.4 0.56 9.7 5.8 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF4200 PF13863.1 KKK14191.1 - 0.5 10.3 12.6 0.58 10.1 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.10 KKK14191.1 - 0.87 8.7 5.3 0.75 8.9 2.8 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Baculo_RING PF05883.6 KKK14191.1 - 1.2 9.0 3.7 0.86 9.4 1.3 1.7 2 0 0 2 2 1 0 Baculovirus U-box/Ring-like domain zf-Apc11 PF12861.2 KKK14191.1 - 1.6 8.6 12.8 0.027 14.3 3.6 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger APG6 PF04111.7 KKK14191.1 - 2.9 6.8 9.6 4.6 6.1 6.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KKK14191.1 - 3.1 5.5 4.2 4.4 5.0 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prok-RING_4 PF14447.1 KKK14191.1 - 4.1 7.0 8.7 27 4.4 4.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Uso1_p115_C PF04871.8 KKK14191.1 - 8.7 6.2 10.3 0.63 9.9 1.7 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Zn_clus PF00172.13 KKK14192.1 - 0.0027 17.5 7.7 0.0058 16.5 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.16 KKK14193.1 - 3.5e-32 109.6 40.5 2.4e-11 43.0 1.8 6.2 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KKK14193.1 - 7.8e-24 84.2 0.0 1.7e-13 50.9 0.0 4.3 1 1 4 5 5 5 4 Prenyltransferase-like dsrm PF00035.20 KKK14193.1 - 0.0005 20.5 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KKK14193.1 - 0.0088 16.3 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Prenyltrans_1 PF13243.1 KKK14193.1 - 0.066 13.2 0.0 5.5 7.0 0.0 3.3 2 1 3 5 5 5 0 Prenyltransferase-like MBOAT PF03062.14 KKK14194.1 - 3.5e-40 138.0 15.9 3.5e-40 138.0 11.0 1.8 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.6 KKK14194.1 - 0.0016 18.4 1.1 0.75 9.8 0.0 2.8 2 0 0 2 2 2 2 PufQ cytochrome subunit Acylphosphatase PF00708.13 KKK14195.1 - 3.3e-21 75.1 0.1 4e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 Acylphosphatase KAR9 PF08580.5 KKK14196.1 - 8.5e-135 450.6 29.3 4e-87 293.1 0.1 3.4 4 0 0 4 4 4 2 Yeast cortical protein KAR9 Ssu72 PF04722.8 KKK14196.1 - 0.15 11.3 0.0 0.45 9.7 0.0 1.8 1 0 0 1 1 1 0 Ssu72-like protein Prefoldin_2 PF01920.15 KKK14196.1 - 0.28 10.9 3.0 1.4 8.7 0.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit Acetyltransf_1 PF00583.19 KKK14197.1 - 0.003 17.5 0.0 0.01 15.8 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KKK14197.1 - 0.0082 16.3 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KKK14197.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK14197.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein AOX PF01786.12 KKK14198.1 - 3e-92 307.6 0.0 3.8e-92 307.3 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase PriCT_1 PF08708.6 KKK14199.1 - 0.15 11.8 1.0 3.4 7.5 0.1 2.9 3 0 0 3 3 3 0 Primase C terminal 1 (PriCT-1) Prefoldin PF02996.12 KKK14200.1 - 1.7e-29 101.8 0.1 2.5e-29 101.3 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KKK14200.1 - 0.00051 19.7 0.1 0.0016 18.1 0.1 1.9 1 1 0 1 1 1 1 Prefoldin subunit RNA_polI_A34 PF08208.6 KKK14201.1 - 1.9e-47 161.5 8.2 1.9e-47 161.5 5.7 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Clp1 PF06807.9 KKK14202.1 - 0.00065 19.5 0.0 0.0059 16.3 0.0 2.4 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KKK14202.1 - 0.00086 19.0 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KKK14202.1 - 0.0031 17.3 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK14202.1 - 0.017 15.9 0.0 0.054 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KKK14202.1 - 0.028 13.8 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KKK14202.1 - 0.071 13.2 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KKK14202.1 - 0.088 13.1 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KKK14202.1 - 0.13 12.4 0.0 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Folliculin PF11704.3 KKK14203.1 - 3.4e-45 153.6 0.0 4.7e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport GRAM PF02893.15 KKK14204.1 - 4.3e-29 99.8 0.9 1e-17 63.4 0.0 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KKK14204.1 - 3.6e-23 81.8 0.0 6.6e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 KKK14204.1 - 2.3e-15 56.6 0.5 1.4e-13 50.9 0.1 2.9 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 KKK14204.1 - 7.4e-07 29.4 0.1 2.6e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KKK14204.1 - 3.2e-05 23.7 0.0 6.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KKK14204.1 - 7.8e-05 22.6 0.1 0.0002 21.3 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 KKK14204.1 - 0.0067 15.0 0.0 0.015 13.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PITH PF06201.8 KKK14206.1 - 2.3e-42 144.3 0.0 3.2e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KKK14206.1 - 3.4e-23 81.3 0.0 6.4e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KKK14206.1 - 8.7e-07 28.9 0.0 0.00013 22.0 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KKK14206.1 - 8.2e-05 22.7 0.1 0.00025 21.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KKK14206.1 - 0.0015 18.1 1.5 0.19 11.2 0.0 2.6 2 1 1 3 3 3 2 Redoxin AhpC-TSA PF00578.16 KKK14206.1 - 0.0035 17.0 0.2 0.083 12.5 0.1 2.5 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 KKK14206.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 KKK14206.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 KKK14206.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.1 KKK14206.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin domain DSBA PF01323.15 KKK14206.1 - 0.06 12.9 0.2 0.14 11.7 0.1 1.6 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.9 KKK14206.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) RNase_T PF00929.19 KKK14207.1 - 0.0019 18.5 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Fructosamin_kin PF03881.9 KKK14208.1 - 0.0058 15.6 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Fork_head PF00250.13 KKK14209.1 - 1.9e-38 130.3 2.0 3.9e-38 129.3 1.4 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KKK14209.1 - 2.2e-08 34.0 0.0 5e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain TENA_THI-4 PF03070.11 KKK14210.1 - 3.4e-17 62.8 0.0 3.1e-07 30.3 0.0 2.9 3 0 0 3 3 3 2 TENA/THI-4/PQQC family PLAC8 PF04749.12 KKK14211.1 - 5e-25 88.1 9.0 5.8e-25 87.9 6.2 1.0 1 0 0 1 1 1 1 PLAC8 family Nol1_Nop2_Fmu PF01189.12 KKK14212.1 - 4.8e-29 101.6 0.0 2.8e-16 59.7 0.0 4.2 2 1 2 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KKK14212.1 - 0.0085 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UNC45-central PF11701.3 KKK14213.1 - 1.7e-37 128.4 1.4 7e-37 126.4 0.1 2.7 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Arm PF00514.18 KKK14213.1 - 2.5e-05 23.9 14.6 4.7 7.1 0.0 8.0 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat TPR_15 PF13429.1 KKK14213.1 - 0.0013 17.8 0.9 0.0048 15.9 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT_2 PF13646.1 KKK14213.1 - 0.0024 18.1 9.9 0.0081 16.4 1.4 4.8 4 1 0 4 4 4 1 HEAT repeats TPR_11 PF13414.1 KKK14213.1 - 0.0097 15.5 0.3 0.021 14.4 0.2 1.6 1 0 0 1 1 1 1 TPR repeat Atx10homo_assoc PF09759.4 KKK14213.1 - 0.019 14.7 0.0 0.099 12.3 0.0 2.3 1 1 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain TIMELESS PF04821.9 KKK14213.1 - 0.07 12.3 0.0 0.53 9.4 0.0 2.2 2 0 0 2 2 2 0 Timeless protein TPR_14 PF13428.1 KKK14213.1 - 0.098 13.3 0.3 0.098 13.3 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_EZ PF13513.1 KKK14213.1 - 2.7 8.5 14.6 20 5.8 0.4 5.7 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.17 KKK14213.1 - 5.4 7.3 6.2 8.3 6.7 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat zf-Tim10_DDP PF02953.10 KKK14215.1 - 1.1e-22 79.0 1.3 1.4e-22 78.7 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger eIF3_subunit PF08597.5 KKK14215.1 - 0.024 14.2 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Condensin2nSMC PF12422.3 KKK14215.1 - 0.044 13.5 0.1 0.054 13.2 0.1 1.1 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Pkinase PF00069.20 KKK14216.1 - 7.3e-69 231.7 0.0 1.1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14216.1 - 2.7e-36 124.9 0.0 4.3e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK14216.1 - 1.5e-05 24.1 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAT1 PF09770.4 KKK14216.1 - 3 5.9 16.0 3.8 5.6 11.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lectin_leg-like PF03388.8 KKK14217.1 - 3.1e-67 226.0 0.1 3.9e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KKK14217.1 - 0.0027 17.1 0.1 0.014 14.7 0.1 1.9 1 1 0 1 1 1 1 Legume lectin domain ATG27 PF09451.5 KKK14217.1 - 0.086 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 SIN1 PF05422.7 KKK14218.1 - 6.1e-32 110.8 5.4 1.6e-17 63.2 5.1 2.7 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KKK14218.1 - 0.035 14.0 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 GLUT4 regulating protein TUG PH PF00169.24 KKK14218.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 PH domain RBM39linker PF15519.1 KKK14218.1 - 0.073 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein RFC1 PF08519.7 KKK14219.1 - 7.9e-61 204.3 0.1 1.2e-59 200.5 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KKK14219.1 - 6.2e-14 51.9 0.0 2.7e-13 49.8 0.0 2.2 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KKK14219.1 - 1.2e-10 41.6 0.3 3.9e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK14219.1 - 1.1e-07 32.0 0.0 3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK14219.1 - 4.6e-05 24.2 5.2 0.00027 21.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KKK14219.1 - 0.00037 20.5 0.0 0.011 15.6 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 KKK14219.1 - 0.0025 17.3 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KKK14219.1 - 0.0039 15.9 0.0 0.016 13.8 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 KKK14219.1 - 0.0068 16.2 0.0 0.023 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 KKK14219.1 - 0.0083 15.7 0.2 0.89 9.1 0.1 2.6 3 0 0 3 3 3 1 Bacterial dnaA protein RuvB_N PF05496.7 KKK14219.1 - 0.0095 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KKK14219.1 - 0.03 14.3 0.1 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KKK14219.1 - 0.03 14.0 0.0 0.33 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KKK14219.1 - 0.033 13.6 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 KKK14219.1 - 0.039 13.6 0.1 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KKK14219.1 - 0.05 13.9 0.1 0.05 13.9 0.0 3.2 4 0 0 4 4 4 0 AAA domain PTCB-BRCT PF12738.2 KKK14219.1 - 0.13 12.1 0.0 0.43 10.4 0.0 2.0 1 0 0 1 1 1 0 twin BRCT domain Glyco_hydro_63 PF03200.11 KKK14220.1 - 1.9e-06 26.0 5.7 6e-05 21.1 0.2 3.5 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase ADIP PF11559.3 KKK14221.1 - 0.011 15.5 1.0 0.016 15.0 0.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SlyX PF04102.7 KKK14221.1 - 0.077 13.3 1.3 0.14 12.5 0.9 1.5 1 0 0 1 1 1 0 SlyX DUF4482 PF14818.1 KKK14221.1 - 0.079 13.6 1.5 0.098 13.3 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) Neugrin PF06413.6 KKK14222.1 - 2.7e-14 53.5 0.3 2.7e-14 53.5 0.2 1.6 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 KKK14222.1 - 2.7e-05 24.1 5.7 9.2e-05 22.4 3.9 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Rgp1 PF08737.5 KKK14223.1 - 3.9e-117 391.8 0.0 6.6e-117 391.0 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 KKK14223.1 - 0.00017 21.4 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KKK14223.1 - 0.014 15.4 0.0 0.36 10.9 0.0 2.8 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.6 KKK14223.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein Mob1_phocein PF03637.12 KKK14224.1 - 1.2e-71 239.9 0.0 1.6e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 KKK14225.1 - 7.3e-44 149.6 2.9 9.4e-44 149.2 2.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.12 KKK14225.1 - 0.12 12.1 1.1 0.39 10.5 0.5 2.0 1 1 2 3 3 3 0 Domain of unknown function DUF148 WD40 PF00400.27 KKK14226.1 - 3.7e-24 83.6 5.7 9e-05 22.2 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat SPO22 PF08631.5 KKK14227.1 - 9.3e-19 67.5 1.5 6.2e-10 38.6 0.0 2.5 1 1 1 2 2 2 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 KKK14227.1 - 0.00067 19.5 0.3 5.3 7.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat HLH PF00010.21 KKK14228.1 - 7.8e-07 28.6 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CtaG_Cox11 PF04442.9 KKK14229.1 - 2.3e-56 189.8 0.0 3.5e-56 189.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Cation_ATPase_C PF00689.16 KKK14229.1 - 0.00044 19.8 0.1 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Rab5ip PF07019.7 KKK14229.1 - 0.64 10.1 3.0 0.37 10.9 0.1 2.2 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) CENP-Q PF13094.1 KKK14231.1 - 3.7e-41 140.8 7.2 3.7e-41 140.8 5.0 1.7 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF904 PF06005.7 KKK14231.1 - 0.017 15.3 6.4 0.017 15.3 4.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) TBPIP PF07106.8 KKK14231.1 - 0.11 12.0 8.7 1.3 8.4 0.0 3.0 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) D5_N PF08706.6 KKK14231.1 - 0.61 10.1 2.9 2.8 8.0 1.9 2.1 1 1 0 1 1 1 0 D5 N terminal like SlyX PF04102.7 KKK14231.1 - 8 6.9 9.8 4.8 7.6 2.0 3.4 4 0 0 4 4 4 0 SlyX Rep_fac_C PF08542.6 KKK14232.1 - 1.7e-23 82.3 0.0 8.4e-23 80.1 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KKK14232.1 - 2.4e-11 43.5 0.1 4.3e-11 42.7 0.1 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KKK14232.1 - 9.6e-06 25.8 0.2 2.3e-05 24.5 0.2 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK14232.1 - 6.2e-05 23.1 0.7 0.00037 20.6 0.4 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK14232.1 - 0.0063 16.5 1.3 0.48 10.3 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 KKK14232.1 - 0.0066 16.5 0.4 0.29 11.1 0.2 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_10 PF12846.2 KKK14232.1 - 0.032 13.6 0.1 1.1 8.5 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 KKK14232.1 - 0.034 14.4 0.1 0.071 13.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 KKK14232.1 - 0.038 13.8 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 KKK14232.1 - 0.045 12.5 0.1 0.065 12.0 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Rad17 PF03215.10 KKK14232.1 - 0.063 11.9 0.0 0.1 11.2 0.0 1.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Ribosomal_L16 PF00252.13 KKK14233.1 - 1e-29 102.9 0.2 1.3e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PNP_UDP_1 PF01048.15 KKK14234.1 - 0.00014 20.8 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Mg_trans_NIPA PF05653.9 KKK14235.1 - 5.1e-91 304.7 22.4 7e-91 304.3 15.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KKK14235.1 - 1.7e-06 28.1 5.0 1.7e-06 28.1 3.4 3.1 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KKK14235.1 - 1.4e-05 25.0 7.4 1.4e-05 25.0 5.2 3.0 3 0 0 3 3 3 1 EamA-like transporter family DUF766 PF05571.7 KKK14236.1 - 0.096 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF766) Cation_ATPase_C PF00689.16 KKK14237.1 - 6 6.3 11.3 35 3.8 7.7 1.9 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus GATase PF00117.23 KKK14238.1 - 4.4e-38 130.6 0.0 7.4e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KKK14238.1 - 5.1e-34 115.8 0.0 1e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KKK14238.1 - 3.9e-10 39.0 0.0 1.4e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KKK14238.1 - 3.8e-06 26.4 0.1 1.2e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 KKK14238.1 - 0.0003 19.4 0.1 0.00089 17.9 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 KKK14238.1 - 0.0032 16.9 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 KKK14238.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 KKK14238.1 - 0.0098 15.1 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 KKK14238.1 - 0.045 12.8 0.1 0.067 12.2 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase Asn_synthase PF00733.16 KKK14238.1 - 0.048 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase LRR_4 PF12799.2 KKK14239.1 - 0.00011 21.7 9.2 0.031 13.8 0.2 4.7 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KKK14239.1 - 0.00031 20.3 0.6 13 6.2 0.0 5.5 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.1 KKK14239.1 - 0.0013 18.5 5.1 1.4 9.1 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich repeat F-box-like PF12937.2 KKK14239.1 - 0.0024 17.5 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KKK14239.1 - 0.0084 15.8 5.1 3.3 7.5 0.1 3.7 3 0 0 3 3 3 2 Leucine rich repeat LURAP PF14854.1 KKK14239.1 - 0.033 13.8 0.5 0.073 12.7 0.3 1.5 1 0 0 1 1 1 0 Leucine rich adaptor protein F-box PF00646.28 KKK14239.1 - 0.036 13.7 1.4 0.27 10.9 0.7 2.7 2 1 0 2 2 2 0 F-box domain LRR_7 PF13504.1 KKK14239.1 - 0.22 11.8 4.3 1.1e+02 3.7 0.0 5.5 5 0 0 5 5 5 0 Leucine rich repeat BSD PF03909.12 KKK14240.1 - 1.4e-27 95.2 13.7 6.4e-15 54.6 0.4 3.5 4 0 0 4 4 4 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KKK14240.1 - 2.5e-27 94.3 0.1 1.7e-26 91.6 0.0 2.3 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Mito_carr PF00153.22 KKK14241.1 - 6.7e-62 205.2 3.6 5.7e-21 74.0 0.0 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Oligomerisation PF02410.10 KKK14242.1 - 0.00019 21.4 0.0 0.0028 17.6 0.0 2.4 1 1 0 1 1 1 1 Oligomerisation domain WAC_Acf1_DNA_bd PF10537.4 KKK14243.1 - 1.1e-41 141.1 1.0 6.1e-41 138.7 0.7 2.4 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KKK14243.1 - 5.4e-19 67.7 2.0 1e-18 66.8 1.4 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KKK14243.1 - 3.6e-09 36.1 0.3 7.6e-09 35.1 0.2 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 KKK14243.1 - 0.00024 20.8 1.1 0.00064 19.4 0.8 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 KKK14243.1 - 0.00048 19.9 0.1 0.00048 19.9 0.1 2.5 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Pex2_Pex12 PF04757.9 KKK14244.1 - 7.5e-59 198.9 2.1 9.4e-59 198.5 1.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KKK14244.1 - 7.2e-06 25.7 3.4 1.3e-05 24.9 2.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KKK14244.1 - 2.1e-05 24.4 3.1 2.1e-05 24.4 2.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK14244.1 - 0.0028 17.4 1.8 0.0028 17.4 1.2 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KKK14244.1 - 0.02 14.5 2.4 0.035 13.7 1.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK14244.1 - 0.11 12.1 1.5 0.2 11.3 1.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 KKK14246.1 - 1.8e-07 30.9 0.1 5.3e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK14246.1 - 4.4e-07 29.3 0.0 0.003 17.3 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KKK14246.1 - 6.5e-07 29.8 0.1 1.3e-06 28.8 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK14246.1 - 1.1e-06 28.7 0.4 0.033 14.8 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK14246.1 - 1.8e-06 27.3 0.0 0.0094 15.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KKK14246.1 - 1.9e-06 27.4 0.0 5.1e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 KKK14246.1 - 7.2e-06 26.2 0.8 1.1e-05 25.6 0.2 1.6 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 KKK14246.1 - 2.6e-05 23.9 0.6 0.19 11.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK14246.1 - 3.7e-05 23.1 0.2 0.017 14.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 KKK14246.1 - 0.00028 20.0 0.1 0.0029 16.7 0.1 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK14246.1 - 0.00063 20.0 0.1 0.088 13.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KKK14246.1 - 0.002 18.2 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KKK14246.1 - 0.0023 17.5 0.0 0.66 9.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KKK14246.1 - 0.0098 15.7 0.1 0.18 11.7 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 KKK14246.1 - 0.063 13.7 0.4 0.38 11.3 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.5 KKK14246.1 - 0.09 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) SIR2 PF02146.12 KKK14247.1 - 3.8e-60 202.6 0.0 5.6e-60 202.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family UPF0020 PF01170.13 KKK14247.1 - 2.3e-08 33.8 0.1 4.8e-06 26.2 0.1 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KKK14247.1 - 8.3e-05 22.6 0.0 0.00023 21.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF592 PF04574.8 KKK14247.1 - 0.00056 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KKK14247.1 - 0.096 12.4 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain HIT PF01230.18 KKK14248.1 - 3.4e-13 49.9 1.5 1.7e-12 47.7 1.0 2.0 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.10 KKK14248.1 - 0.0072 15.9 0.3 0.02 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 DcpS_C PF11969.3 KKK14248.1 - 0.0076 16.4 1.6 0.12 12.5 1.1 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding RWD PF05773.17 KKK14249.1 - 7.2e-24 83.8 1.0 1.4e-23 82.9 0.7 1.5 1 0 0 1 1 1 1 RWD domain KBP_C PF12309.3 KKK14249.1 - 0.32 9.9 7.7 0.42 9.5 5.3 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Complex1_LYR_1 PF13232.1 KKK14250.1 - 1.2e-17 63.8 0.1 1.2e-17 63.8 0.1 2.7 3 0 0 3 3 3 1 Complex1_LYR-like Complex1_LYR PF05347.10 KKK14250.1 - 7.3e-17 60.9 2.1 9.3e-17 60.5 0.1 2.2 2 1 1 3 3 3 1 Complex 1 protein (LYR family) WD40 PF00400.27 KKK14251.1 - 1.9e-25 87.7 12.0 2.2e-10 39.9 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 KKK14251.1 - 0.00015 20.0 0.2 0.092 10.8 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KKK14251.1 - 0.0036 17.0 0.0 0.78 9.4 0.0 2.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KKK14251.1 - 0.018 14.5 0.0 0.05 13.1 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 KKK14251.1 - 0.029 14.0 2.5 3.3 7.3 0.6 3.7 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Cytochrom_D1 PF02239.11 KKK14251.1 - 0.07 11.4 0.0 0.85 7.8 0.1 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 KKK14251.1 - 0.17 10.6 0.0 0.39 9.4 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region Fungal_trans PF04082.13 KKK14252.1 - 8.9e-21 73.9 0.0 2e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14252.1 - 1.1e-09 38.0 12.0 2.1e-09 37.1 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_U34 PF04541.8 KKK14252.1 - 0.028 13.3 1.0 0.051 12.4 0.7 1.3 1 0 0 1 1 1 0 Herpesvirus virion protein U34 DUF655 PF04919.7 KKK14252.1 - 0.31 10.7 0.0 0.56 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Ribosomal_L2_C PF03947.13 KKK14253.1 - 3.1e-47 159.6 1.0 5.3e-33 113.5 0.5 2.4 1 1 1 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KKK14253.1 - 1.8e-26 91.8 0.2 4.7e-26 90.5 0.1 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PAS PF00989.19 KKK14253.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 PAS fold Cyclin_N PF00134.18 KKK14254.1 - 1.4e-45 153.9 0.1 1.5e-44 150.5 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KKK14254.1 - 1.2e-33 115.5 0.0 3.4e-33 114.0 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Dna2 PF08696.6 KKK14255.1 - 2.5e-71 239.3 1.4 4.4e-71 238.4 1.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KKK14255.1 - 2.9e-52 176.9 0.0 5.1e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK14255.1 - 7.2e-42 143.5 0.3 1.6e-21 77.0 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KKK14255.1 - 1.3e-13 50.9 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK14255.1 - 1.3e-11 44.0 0.1 3.2e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 KKK14255.1 - 5e-11 42.4 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 KKK14255.1 - 3.4e-08 33.5 0.1 1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 KKK14255.1 - 3.4e-07 30.0 0.1 0.35 10.3 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KKK14255.1 - 6.8e-05 22.5 0.0 0.00023 20.8 0.0 2.0 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 KKK14255.1 - 0.00061 19.1 1.8 0.0012 18.2 0.1 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain CbiA PF01656.18 KKK14255.1 - 0.00074 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KKK14255.1 - 0.0011 18.6 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KKK14255.1 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KKK14255.1 - 0.0021 18.1 0.0 0.0063 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.9 KKK14255.1 - 0.0071 15.3 0.2 0.2 10.5 0.0 2.4 3 0 0 3 3 3 1 PIF1-like helicase DUF2075 PF09848.4 KKK14255.1 - 0.029 13.3 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KKK14255.1 - 0.035 13.5 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KKK14255.1 - 0.043 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF87 PF01935.12 KKK14255.1 - 0.045 13.5 0.2 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF87 ResIII PF04851.10 KKK14255.1 - 0.062 13.1 0.2 0.19 11.5 0.1 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KKK14255.1 - 0.07 13.2 0.1 0.28 11.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KKK14255.1 - 0.087 13.0 0.2 0.31 11.2 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KKK14255.1 - 0.096 11.4 0.1 0.24 10.1 0.1 1.6 1 0 0 1 1 1 0 ArgK protein AAA_5 PF07728.9 KKK14255.1 - 0.1 12.3 0.0 0.35 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribonuc_P_40 PF08584.6 KKK14256.1 - 4e-94 314.7 0.0 4.9e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit CN_hydrolase PF00795.17 KKK14257.1 - 1.4e-27 96.2 0.0 1.6e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ESSS PF10183.4 KKK14258.1 - 2.5e-30 104.9 0.0 2.9e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3961 PF13106.1 KKK14258.1 - 0.34 10.5 2.1 0.53 9.8 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) RNB PF00773.14 KKK14259.1 - 5.6e-95 318.3 0.1 1e-94 317.4 0.0 1.4 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KKK14259.1 - 1.8e-08 34.5 0.3 4.5e-08 33.2 0.2 1.7 1 0 0 1 1 1 1 PIN domain Gti1_Pac2 PF09729.4 KKK14260.1 - 1.1e-51 175.0 0.7 7e-51 172.4 0.5 1.9 1 1 0 1 1 1 1 Gti1/Pac2 family Peptidase_C54 PF03416.14 KKK14269.1 - 8.8e-94 313.7 0.0 1.1e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.19 KKK14270.1 - 8e-26 89.9 0.0 1.1e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KKK14270.1 - 1.2e-05 25.3 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK14271.1 - 2.9e-22 78.5 0.3 4.1e-22 78.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KKK14271.1 - 0.00039 20.4 0.0 0.00039 20.4 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KKK14271.1 - 0.00041 20.5 0.0 0.00068 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 KKK14271.1 - 0.017 14.5 0.1 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain 2-oxoacid_dh PF00198.18 KKK14272.1 - 3.3e-80 268.6 0.0 5.4e-80 267.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KKK14272.1 - 1.5e-19 69.3 2.0 2.7e-19 68.5 1.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 KKK14272.1 - 2e-05 23.9 2.4 0.00044 19.4 0.3 2.5 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 KKK14272.1 - 0.0039 16.8 0.4 0.13 11.9 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.1 KKK14272.1 - 0.0046 16.6 0.2 0.031 13.9 0.1 2.3 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 KKK14272.1 - 0.016 14.9 0.4 0.032 13.8 0.3 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_3 PF13437.1 KKK14272.1 - 0.023 15.0 0.2 0.91 9.9 0.1 2.3 1 1 1 2 2 2 0 HlyD family secretion protein DUF2360 PF10152.4 KKK14272.1 - 0.68 10.2 8.4 1.3 9.3 5.8 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) FAP PF07174.6 KKK14272.1 - 3.2 6.9 16.6 5.1 6.3 11.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Complex1_LYR PF05347.10 KKK14273.1 - 1.7e-09 37.2 0.3 2.7e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK14273.1 - 5.6e-07 29.6 0.2 8e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DnaJ PF00226.26 KKK14274.1 - 1.7e-25 88.5 2.2 1.7e-25 88.5 1.5 2.7 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 KKK14274.1 - 4.4e-17 61.4 1.8 3.7e-08 32.8 0.0 5.9 5 2 3 8 8 8 5 TPR repeat TPR_1 PF00515.23 KKK14274.1 - 1.9e-14 52.5 0.1 2.2e-06 27.0 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK14274.1 - 1.7e-13 49.3 2.1 0.0005 19.7 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK14274.1 - 4.6e-12 45.4 6.5 0.039 14.5 0.5 6.7 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 KKK14274.1 - 1.9e-11 43.6 3.6 3.2e-05 23.7 0.4 4.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 KKK14274.1 - 8.6e-11 42.2 12.1 0.00028 21.4 1.2 5.2 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 KKK14274.1 - 3.5e-10 40.0 2.0 9.4e-05 22.6 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK14274.1 - 8.7e-06 25.1 0.0 0.086 12.6 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK14274.1 - 4.9e-05 23.1 6.3 0.043 13.7 0.2 4.5 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK14274.1 - 8.1e-05 22.5 3.6 0.55 10.5 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KKK14274.1 - 0.00073 19.6 7.3 0.071 13.2 0.1 4.7 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KKK14274.1 - 0.0018 18.5 10.6 5 7.7 0.0 7.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK14274.1 - 0.0067 16.1 0.6 6.2 6.8 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat PCMT PF01135.14 KKK14275.1 - 5.7e-55 186.0 0.0 1.7e-54 184.5 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KKK14275.1 - 1.5e-10 41.6 0.0 2.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK14275.1 - 4e-09 36.2 0.0 5.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK14275.1 - 6.1e-06 26.5 0.0 9.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK14275.1 - 6.2e-06 26.0 0.0 8.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KKK14275.1 - 2.8e-05 23.8 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK14275.1 - 3.9e-05 23.6 0.0 5.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK14275.1 - 0.002 18.5 0.0 0.0032 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK14275.1 - 0.005 17.3 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KKK14275.1 - 0.0055 16.0 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 KKK14275.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KKK14275.1 - 0.032 13.3 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KKK14275.1 - 0.042 12.9 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCD14 PF08704.5 KKK14275.1 - 0.069 12.6 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 KKK14275.1 - 0.076 12.0 0.0 0.098 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 KKK14275.1 - 0.12 11.4 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Bestrophin PF01062.16 KKK14276.1 - 3.5e-16 58.9 0.1 1.1e-15 57.3 0.1 1.6 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FHA PF00498.21 KKK14276.1 - 2.2e-13 50.0 0.0 4.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KKK14276.1 - 9.4e-06 25.3 9.3 2.4e-05 24.0 6.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KKK14276.1 - 0.01 15.9 6.3 0.021 14.9 4.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 KKK14276.1 - 0.011 15.4 6.3 0.021 14.5 4.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 KKK14276.1 - 0.071 12.9 2.8 0.15 11.9 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KKK14276.1 - 0.14 12.1 9.5 0.32 11.0 6.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK14276.1 - 0.32 10.7 9.5 0.28 10.8 5.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KKK14276.1 - 0.32 11.0 6.1 0.78 9.7 4.2 1.7 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 KKK14276.1 - 0.44 10.2 6.0 0.81 9.4 4.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-H2C2_2 PF13465.1 KKK14276.1 - 0.57 10.5 2.5 0.74 10.2 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double domain MS_channel PF00924.13 KKK14277.1 - 8e-23 80.8 1.8 8e-23 80.8 1.2 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KKK14277.1 - 0.00021 20.3 0.5 0.00054 19.0 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KKK14277.1 - 0.00092 18.9 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KKK14277.1 - 0.0012 18.1 0.0 0.0029 16.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KKK14277.1 - 0.0013 18.7 0.2 0.0033 17.5 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair DUF2763 PF10961.3 KKK14277.1 - 2.7 8.4 5.6 14 6.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) DUF3384 PF11864.3 KKK14281.1 - 1.5e-101 340.2 0.7 2.3e-101 339.5 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KKK14281.1 - 9.2e-56 188.1 0.0 1.5e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KKK14281.1 - 1.2e-28 100.1 0.9 2e-27 96.2 0.0 2.6 3 0 0 3 3 3 1 Tuberin DUF2435 PF10363.4 KKK14281.1 - 0.056 13.3 0.1 22 5.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) CAS_CSE1 PF03378.10 KKK14282.1 - 3.4e-183 608.9 0.0 9.5e-183 607.4 0.0 1.8 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KKK14282.1 - 1e-156 521.1 1.6 1.5e-156 520.6 1.1 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KKK14282.1 - 9.6e-15 54.2 0.2 3.9e-14 52.3 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KKK14282.1 - 0.006 16.5 4.4 0.038 13.8 0.0 4.3 6 0 0 6 6 6 1 Exportin 1-like protein HEAT_2 PF13646.1 KKK14282.1 - 0.077 13.2 0.0 1.9 8.8 0.0 3.0 2 0 0 2 2 2 0 HEAT repeats Podoplanin PF05808.6 KKK14283.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Podoplanin DUF3377 PF11857.3 KKK14283.1 - 0.11 12.1 0.1 0.69 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Phosphodiest PF01663.17 KKK14284.1 - 6.6e-14 51.9 0.4 1.3e-13 51.0 0.3 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KKK14284.1 - 2.3e-06 27.2 0.3 3.9e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KKK14284.1 - 0.00017 20.8 0.1 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Gly-zipper_YMGG PF13441.1 KKK14284.1 - 0.25 10.9 4.2 0.55 9.7 2.9 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF1640 PF07798.6 KKK14285.1 - 1.2e-10 41.7 3.8 1.9e-10 41.0 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Syntaxin-6_N PF09177.6 KKK14285.1 - 0.13 12.6 2.8 0.32 11.4 1.6 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ALMT PF11744.3 KKK14285.1 - 0.31 9.6 2.6 0.44 9.1 1.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Vps51 PF08700.6 KKK14286.1 - 4e-16 58.6 0.2 4.1e-15 55.3 0.0 2.8 2 0 0 2 2 2 1 Vps51/Vps67 Uso1_p115_head PF04869.9 KKK14286.1 - 0.014 14.1 0.4 0.032 12.9 0.1 1.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region Apolipoprotein PF01442.13 KKK14286.1 - 0.15 11.5 6.7 0.5 9.8 0.6 3.0 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 KKK14286.1 - 0.84 10.0 3.5 16 5.9 0.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) D123 PF07065.9 KKK14287.1 - 1.9e-90 302.9 0.0 2.5e-88 296.0 0.0 2.1 1 1 1 2 2 2 2 D123 ECH PF00378.15 KKK14288.1 - 6.2e-28 97.5 0.0 7.6e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2346 PF09803.4 KKK14289.1 - 0.0052 16.6 4.3 0.013 15.3 3.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) DUF3317 PF11779.3 KKK14290.1 - 1.5e-24 85.1 3.2 2.6e-24 84.4 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) RF-1 PF00472.15 KKK14291.1 - 1.4e-25 89.2 2.2 1.9e-25 88.8 1.5 1.2 1 0 0 1 1 1 1 RF-1 domain B56 PF01603.15 KKK14295.1 - 2.3e-173 576.5 8.5 2.8e-173 576.2 5.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) TPR_11 PF13414.1 KKK14296.1 - 3.8e-10 39.2 4.1 8.1e-08 31.8 1.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KKK14296.1 - 2.3e-05 23.9 3.5 1.3 9.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK14296.1 - 6.2e-05 22.4 0.7 2.8 7.6 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KKK14296.1 - 0.00045 20.0 4.6 0.084 12.8 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK14296.1 - 0.00098 18.7 1.4 0.78 9.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KKK14296.1 - 0.0065 16.3 4.0 0.063 13.1 0.5 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK14296.1 - 0.04 14.0 0.0 0.094 12.8 0.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KKK14296.1 - 0.084 13.5 0.3 0.084 13.5 0.2 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK14296.1 - 0.61 10.0 0.0 0.61 10.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK14296.1 - 1.8 9.4 12.7 4.9 8.0 0.0 3.9 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK14296.1 - 7.6 7.2 0.0 7.6 7.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MARVEL PF01284.18 KKK14326.1 - 0.0015 18.3 0.2 0.0023 17.7 0.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain TFIIA PF03153.8 KKK14327.1 - 3.6 7.3 9.7 8.4 6.1 6.8 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD PF00628.24 KKK14328.1 - 1e-09 37.9 2.7 2.5e-09 36.7 1.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KKK14328.1 - 0.0096 15.2 3.4 0.016 14.5 2.4 1.3 1 0 0 1 1 1 1 PHD-finger eIF-5a PF01287.15 KKK14329.1 - 0.00018 21.3 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Fungal_trans PF04082.13 KKK14330.1 - 6.1e-21 74.4 0.3 9.1e-21 73.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 KKK14331.1 - 5.3e-84 280.5 60.6 1.7e-44 151.4 14.1 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KKK14331.1 - 2.8e-37 128.0 0.1 1.5e-17 64.1 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KKK14331.1 - 2.3e-36 123.5 6.7 6.7e-34 115.6 0.0 3.7 3 0 0 3 3 3 1 CDR ABC transporter ABC_trans_N PF14510.1 KKK14331.1 - 5.7e-20 71.1 0.1 5.7e-20 71.1 0.1 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KKK14331.1 - 2.2e-08 33.7 0.2 7.9e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KKK14331.1 - 4.6e-06 25.9 0.1 0.002 17.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK14331.1 - 8.8e-06 25.8 2.2 0.00026 21.0 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KKK14331.1 - 0.00028 20.3 2.0 0.019 14.4 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KKK14331.1 - 0.00047 20.0 0.4 0.0079 16.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KKK14331.1 - 0.0015 17.9 1.0 0.074 12.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KKK14331.1 - 0.0027 17.8 0.5 1.2 9.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KKK14331.1 - 0.0033 17.0 0.9 2.2 7.9 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 KKK14331.1 - 0.0069 16.1 0.6 4 7.2 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KKK14331.1 - 0.007 16.6 0.1 0.3 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KKK14331.1 - 0.015 14.5 0.0 2.5 7.2 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain PDR_assoc PF08370.6 KKK14331.1 - 0.018 14.5 3.2 0.035 13.6 0.2 2.7 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AAA_21 PF13304.1 KKK14331.1 - 0.027 14.4 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KKK14331.1 - 0.055 14.2 0.0 0.87 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KKK14331.1 - 0.07 13.6 0.0 8.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 KKK14331.1 - 0.1 12.1 0.6 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KKK14331.1 - 0.13 12.4 0.1 26 5.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KKK14331.1 - 0.13 11.7 0.2 1.5 8.2 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 KKK14331.1 - 0.16 11.6 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 KKK14331.1 - 0.18 11.7 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase PMT PF02366.13 KKK14332.1 - 4.8e-77 258.6 17.0 1.1e-76 257.4 11.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KKK14332.1 - 4.1e-53 179.7 0.0 6.4e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 MIR domain DUF4231 PF14015.1 KKK14332.1 - 1.1 9.2 5.6 0.59 10.1 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PRP21_like_P PF12230.3 KKK14333.1 - 1.2e-64 217.9 13.3 1.9e-64 217.2 9.2 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KKK14333.1 - 3.8e-36 122.5 6.0 2.9e-19 68.4 0.1 2.7 3 0 0 3 3 3 2 Surp module dsDNA_bind PF01984.15 KKK14335.1 - 1.3e-36 124.8 15.0 1.5e-36 124.6 10.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 KKK14335.1 - 0.0024 18.0 1.1 0.0037 17.4 0.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4615) Protamine_P2 PF00841.14 KKK14335.1 - 1.6 9.3 4.5 0.32 11.5 0.3 2.0 1 1 1 2 2 2 0 Sperm histone P2 Rap1_C PF11626.3 KKK14335.1 - 5 7.0 6.1 5.9 6.8 0.5 2.6 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sec2p PF06428.6 KKK14336.1 - 1.3e-27 95.6 12.2 1.3e-27 95.6 8.4 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.3 KKK14336.1 - 0.0007 17.0 16.7 0.001 16.5 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 KKK14336.1 - 0.0012 18.1 4.8 0.028 13.6 3.7 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein DUF1759 PF03564.10 KKK14336.1 - 0.39 10.5 6.1 0.13 12.0 0.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) Atg14 PF10186.4 KKK14336.1 - 0.72 8.7 19.5 0.66 8.8 7.6 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 3-PAP PF12578.3 KKK14336.1 - 3.2 7.6 8.3 0.29 10.9 0.6 2.9 3 1 1 4 4 4 0 Myotubularin-associated protein IncA PF04156.9 KKK14336.1 - 4.3 6.8 21.3 0.93 9.0 3.2 2.4 1 1 1 2 2 2 0 IncA protein Filament PF00038.16 KKK14336.1 - 5 6.4 24.5 2 7.8 14.4 2.2 2 1 0 2 2 2 0 Intermediate filament protein SET PF00856.23 KKK14337.1 - 4.8e-20 72.4 0.0 7.8e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 SET domain Coq4 PF05019.8 KKK14338.1 - 8.5e-100 332.2 0.0 1e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Sas10_Utp3 PF04000.10 KKK14339.1 - 1.8e-19 69.7 0.7 4.3e-19 68.4 0.5 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CHCH PF06747.8 KKK14339.1 - 0.00023 21.0 1.8 0.00051 19.8 1.2 1.7 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 KKK14339.1 - 0.069 13.1 28.8 0.21 11.6 20.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Hid1 PF12722.2 KKK14339.1 - 0.14 9.8 5.7 0.18 9.4 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 KKK14339.1 - 0.72 8.0 7.4 0.96 7.6 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Suf PF05843.9 KKK14339.1 - 1.5 8.4 7.2 2.2 7.9 5.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF566 PF04484.7 KKK14339.1 - 2.3 7.6 10.4 3.9 6.9 7.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Band_3_cyto PF07565.8 KKK14339.1 - 3 7.2 5.5 0.54 9.7 1.2 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CDC45 PF02724.9 KKK14339.1 - 7.1 4.5 9.0 10 4.0 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ApbA_C PF08546.6 KKK14340.1 - 4.9e-35 120.2 0.1 8.2e-35 119.5 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KKK14340.1 - 4.9e-26 90.9 0.0 1.4e-24 86.2 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SURF1 PF02104.10 KKK14341.1 - 1.9e-68 230.4 0.0 2.5e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 KKK14342.1 - 5.1e-09 36.0 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain DUF4366 PF14283.1 KKK14342.1 - 0.18 11.2 0.0 0.18 11.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) CDC27 PF09507.5 KKK14342.1 - 1.1 8.4 17.3 1.8 7.6 12.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CMS1 PF14617.1 KKK14343.1 - 5.4e-59 199.2 9.0 1.1e-58 198.2 5.2 2.1 1 1 2 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KKK14343.1 - 2.7e-05 23.7 0.0 3.7e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Dicty_REP PF05086.7 KKK14343.1 - 0.2 9.3 2.0 0.25 9.0 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CENP-T PF15511.1 KKK14344.1 - 9.9e-102 341.2 7.5 9.9e-102 341.2 5.2 2.0 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 KKK14344.1 - 7e-09 35.7 0.1 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KKK14344.1 - 1.8e-05 24.7 0.1 3.3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF531 PF04407.7 KKK14344.1 - 0.0051 16.7 0.0 0.0076 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF531) CBFD_NFYB_HMF PF00808.18 KKK14344.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aldedh PF00171.17 KKK14352.1 - 2.7e-97 326.0 0.1 3.6e-97 325.5 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HnRNPA1 PF11627.3 KKK14352.1 - 0.19 11.8 0.7 0.4 10.8 0.5 1.5 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 Cys_Met_Meta_PP PF01053.15 KKK14354.1 - 1.4e-11 43.2 0.0 1.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TauD PF02668.11 KKK14355.1 - 1.3e-42 146.3 0.0 2.1e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LCD1 PF09798.4 KKK14355.1 - 0.058 11.3 0.0 0.081 10.9 0.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Asp_protease PF09668.5 KKK14356.1 - 2.4e-61 204.7 0.1 3.7e-61 204.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KKK14356.1 - 6.1e-11 42.6 0.0 1.5e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 KKK14356.1 - 1.8e-09 36.8 0.0 3.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 KKK14356.1 - 4.8e-06 26.2 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 KKK14356.1 - 6e-06 25.9 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 KKK14356.1 - 1.2e-05 25.2 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KKK14356.1 - 0.00034 20.4 0.0 0.00085 19.2 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 KKK14356.1 - 0.0097 15.4 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Rad60-SLD PF11976.3 KKK14356.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NAD_binding_7 PF13241.1 KKK14356.1 - 0.08 13.2 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF2781 PF10914.3 KKK14357.1 - 1e-39 135.7 7.2 1.2e-39 135.5 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF962 PF06127.6 KKK14357.1 - 0.17 11.7 0.6 0.35 10.7 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Peptidase_S10 PF00450.17 KKK14367.1 - 2.6e-115 385.8 0.0 3.2e-115 385.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KKK14367.1 - 0.00023 21.0 0.0 0.00058 19.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Myc_target_1 PF15179.1 KKK14367.1 - 0.018 14.6 0.2 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 Myc target protein 1 Act-Frag_cataly PF09192.5 KKK14367.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic SKG6 PF08693.5 KKK14367.1 - 9.3 5.6 7.2 17 4.8 5.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RNA_Me_trans PF04252.8 KKK14369.1 - 4.7e-49 166.4 0.0 5.4e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase bPH_5 PF10882.3 KKK14369.1 - 0.096 12.4 0.1 12 5.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial PH domain FAD_binding_2 PF00890.19 KKK14370.1 - 2.3e-125 418.7 3.4 3.4e-125 418.1 2.4 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KKK14370.1 - 2e-46 157.0 1.5 2.9e-46 156.4 1.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KKK14370.1 - 3e-07 30.5 0.0 0.0031 17.4 0.6 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK14370.1 - 1.7e-05 24.0 0.2 0.012 14.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KKK14370.1 - 2.2e-05 23.5 1.3 0.036 12.9 1.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 KKK14370.1 - 7.2e-05 21.8 0.2 0.001 18.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK14370.1 - 0.0094 15.0 0.2 0.0094 15.0 0.1 1.9 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 KKK14370.1 - 0.12 10.8 1.1 0.51 8.7 0.4 2.3 3 0 0 3 3 3 0 HI0933-like protein AAA PF00004.24 KKK14371.1 - 2.4e-40 137.8 0.0 4.1e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK14371.1 - 5e-06 26.6 0.0 0.00061 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KKK14371.1 - 4.4e-05 23.2 0.1 0.00028 20.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK14371.1 - 0.00025 21.0 0.1 0.0012 18.8 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_2 PF07724.9 KKK14371.1 - 0.00043 20.2 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KKK14371.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KKK14371.1 - 0.0034 18.2 0.1 0.012 16.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KKK14371.1 - 0.0098 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK14371.1 - 0.0099 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KKK14371.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK14371.1 - 0.017 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK14371.1 - 0.032 14.0 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KKK14371.1 - 0.051 13.1 0.0 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KKK14371.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 KKK14371.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KKK14371.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 KKK14371.1 - 0.098 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KKK14371.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KKK14371.1 - 0.1 12.8 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KKK14371.1 - 0.14 11.5 0.2 0.48 9.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain p450 PF00067.17 KKK14372.1 - 2.1e-23 82.5 0.0 2.4e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PARP PF00644.15 KKK14373.1 - 7.8e-65 218.1 0.9 1.1e-64 217.7 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KKK14373.1 - 1.9e-42 144.1 0.1 2.9e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KKK14373.1 - 9.8e-22 76.7 0.3 2.3e-21 75.5 0.2 1.7 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 KKK14373.1 - 5.3e-09 36.0 0.3 1.5e-08 34.6 0.2 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KKK14373.1 - 5.8e-08 32.4 0.3 1.2e-07 31.4 0.2 1.5 1 0 0 1 1 1 1 twin BRCT domain Ribosomal_60s PF00428.14 KKK14373.1 - 0.013 15.9 3.1 0.031 14.6 2.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Cpn60_TCP1 PF00118.19 KKK14374.1 - 1.4e-139 465.9 10.9 1.7e-139 465.5 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KKK14374.1 - 0.041 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X GTP1_OBG PF01018.17 KKK14374.1 - 0.077 12.6 0.1 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 GTP1/OBG DUF2277 PF10041.4 KKK14374.1 - 0.09 12.7 0.2 4.3 7.3 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) zf-C2H2 PF00096.21 KKK14375.1 - 0.00037 20.6 4.1 0.00037 20.6 2.9 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK14375.1 - 0.028 14.7 18.0 0.041 14.2 1.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.7 KKK14375.1 - 0.11 12.4 0.2 0.11 12.4 0.1 2.3 3 0 0 3 3 3 0 TFIIH C1-like domain zf-H2C2_2 PF13465.1 KKK14375.1 - 1.2 9.5 18.7 1.3 9.4 3.6 3.7 3 0 0 3 3 3 0 Zinc-finger double domain MFS_1 PF07690.11 KKK14427.1 - 2.1e-22 79.3 52.3 3.6e-19 68.6 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_20 PF00982.16 KKK14428.1 - 2e-149 498.0 0.0 2.7e-149 497.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KKK14428.1 - 4.8e-91 303.8 0.0 7.1e-91 303.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 KKK14428.1 - 0.0011 18.5 0.0 0.58 9.6 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK14428.1 - 0.087 12.9 0.1 0.73 9.9 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PP28 PF10252.4 KKK14429.1 - 1.3e-31 108.4 13.9 1.3e-31 108.4 9.7 3.2 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 CAF-1_p150 PF11600.3 KKK14429.1 - 0.99 8.7 29.3 0.19 11.0 6.8 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4611 PF15387.1 KKK14429.1 - 5.3 7.2 14.0 4.9 7.3 5.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 KKK14429.1 - 8.2 6.7 17.9 4.3 7.6 7.5 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cyto_heme_lyase PF01265.12 KKK14430.1 - 2.7e-82 276.2 0.0 3.2e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.11 KKK14431.1 - 7.9e-24 83.9 0.0 9.3e-14 51.4 0.0 2.8 3 0 0 3 3 3 2 ABC1 family RIO1 PF01163.17 KKK14431.1 - 0.034 13.5 0.0 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KKK14431.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Bac_surface_Ag PF01103.18 KKK14432.1 - 1.3e-38 133.3 0.2 1.7e-38 132.9 0.2 1.2 1 0 0 1 1 1 1 Surface antigen AAA PF00004.24 KKK14433.1 - 1.2e-43 148.4 0.0 2.1e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK14433.1 - 2e-08 34.0 0.0 4.6e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KKK14433.1 - 1.1e-07 31.9 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KKK14433.1 - 2.3e-06 27.7 0.1 1.3e-05 25.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK14433.1 - 3.9e-06 27.0 0.1 0.00023 21.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK14433.1 - 9.9e-05 23.1 0.0 0.00023 21.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KKK14433.1 - 0.00013 21.1 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK14433.1 - 0.00013 21.6 0.1 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KKK14433.1 - 0.00039 19.8 0.0 0.00073 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KKK14433.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KKK14433.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK14433.1 - 0.0021 17.9 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK14433.1 - 0.0026 16.8 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 KKK14433.1 - 0.0038 17.1 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KKK14433.1 - 0.0039 16.7 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KKK14433.1 - 0.0041 16.3 0.1 0.015 14.4 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KKK14433.1 - 0.0054 15.8 0.0 0.017 14.2 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 KKK14433.1 - 0.0061 16.8 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KKK14433.1 - 0.019 14.3 0.1 0.066 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KKK14433.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KKK14433.1 - 0.02 14.1 0.0 0.076 12.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 KKK14433.1 - 0.02 14.3 0.1 0.096 12.1 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 KKK14433.1 - 0.02 13.8 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2072 PF09845.4 KKK14433.1 - 0.028 14.3 0.3 0.075 12.9 0.1 1.8 2 0 0 2 2 1 0 Zn-ribbon containing protein (DUF2072) RNA_helicase PF00910.17 KKK14433.1 - 0.033 14.3 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KKK14433.1 - 0.047 13.7 0.0 0.15 12.1 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KKK14433.1 - 0.05 12.4 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KKK14433.1 - 0.068 12.8 0.0 0.53 9.9 0.0 2.1 1 1 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 KKK14433.1 - 0.079 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 KKK14433.1 - 0.097 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 UQ_con PF00179.21 KKK14435.1 - 6.2e-26 90.4 0.1 8.7e-26 90.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RibD_C PF01872.12 KKK14436.1 - 1.2e-20 74.0 0.0 4.7e-20 72.0 0.0 1.9 1 1 0 1 1 1 1 RibD C-terminal domain PAT1 PF09770.4 KKK14436.1 - 0.69 8.0 15.2 0.95 7.6 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neisseria_TspB PF05616.8 KKK14436.1 - 3.5 5.8 7.3 5.4 5.2 5.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF605 PF04652.11 KKK14436.1 - 6.3 6.0 18.6 9.7 5.4 12.9 1.2 1 0 0 1 1 1 0 Vta1 like F-box PF00646.28 KKK14438.1 - 0.032 13.8 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 F-box domain HTH_AraC PF00165.18 KKK14438.1 - 0.047 13.5 1.1 0.15 11.9 0.8 1.9 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family F-box-like_2 PF13013.1 KKK14438.1 - 0.049 13.3 0.2 0.97 9.1 0.0 2.6 3 0 0 3 3 3 0 F-box-like domain Y_phosphatase PF00102.22 KKK14439.1 - 1.5e-60 204.5 5.3 1.6e-60 204.3 0.0 2.8 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KKK14439.1 - 7.2e-12 45.6 0.0 3.5e-10 40.2 0.0 2.8 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 KKK14439.1 - 0.0029 17.1 1.4 0.0033 17.0 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KKK14439.1 - 0.0089 16.2 2.0 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Activator_LAG-3 PF11498.3 KKK14439.1 - 0.027 13.2 14.6 0.046 12.4 10.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 COX16 PF14138.1 KKK14440.1 - 1.3e-30 105.3 0.2 1.6e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 SDP_N PF12278.3 KKK14440.1 - 0.025 14.2 2.4 0.035 13.7 1.7 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal DPM3 PF08285.6 KKK14441.1 - 8.7e-30 102.4 0.7 2.7e-28 97.6 0.0 2.0 2 0 0 2 2 2 2 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Nic96 PF04097.9 KKK14442.1 - 9.6e-210 697.8 0.0 1.1e-209 697.5 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 KKK14442.1 - 2.9e-06 27.5 28.7 2.9e-06 27.5 19.9 2.4 2 0 0 2 2 2 1 Nucleoporin FG repeat region Na_Ca_ex PF01699.19 KKK14443.1 - 4.1e-30 104.2 23.9 7.7e-18 64.4 6.8 4.5 6 0 0 6 6 6 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KKK14443.1 - 1.1e-14 54.5 12.3 1.1e-14 54.5 8.5 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF307) TFIIA PF03153.8 KKK14443.1 - 0.11 12.3 15.1 0.22 11.3 10.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tom22 PF04281.8 KKK14443.1 - 0.7 9.4 3.9 1.9 7.9 2.7 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Nop14 PF04147.7 KKK14443.1 - 8.1 4.2 16.3 12 3.6 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family FGGY_C PF02782.11 KKK14444.1 - 3.4e-50 170.4 0.1 6.1e-50 169.5 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KKK14444.1 - 7.4e-25 87.6 0.1 9.3e-24 84.0 0.1 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KKK14444.1 - 0.01 15.1 0.0 0.039 13.2 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family UFD1 PF03152.9 KKK14445.1 - 8.5e-24 83.6 0.0 2e-12 46.5 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 zinc_ribbon_5 PF13719.1 KKK14445.1 - 0.17 11.5 4.2 13 5.4 0.0 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KKK14445.1 - 0.19 11.4 4.3 9.8 5.9 0.0 3.6 3 0 0 3 3 3 0 zinc-ribbon domain CAF-1_p150 PF11600.3 KKK14445.1 - 9.8 5.4 7.9 4.4 6.6 2.0 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Yip1 PF04893.12 KKK14446.1 - 9.2e-06 25.2 19.4 0.00048 19.6 7.0 2.4 2 0 0 2 2 2 2 Yip1 domain Sporozoite_P67 PF05642.6 KKK14446.1 - 0.43 8.3 6.2 0.84 7.4 4.3 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen ILVD_EDD PF00920.16 KKK14450.1 - 2.1e-201 669.9 0.8 2.4e-201 669.6 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family FTCD_C PF04961.7 KKK14450.1 - 0.089 12.1 0.4 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Abhydrolase_6 PF12697.2 KKK14451.1 - 1e-22 81.1 0.0 1.7e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK14451.1 - 2.8e-20 72.8 0.0 1.6e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK14451.1 - 2.5e-07 30.5 0.0 1.7e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KKK14451.1 - 0.00079 17.9 0.0 0.0011 17.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family SR-25 PF10500.4 KKK14451.1 - 0.0083 15.6 10.9 0.014 14.9 7.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Abhydrolase_4 PF08386.5 KKK14451.1 - 0.0092 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF4611 PF15387.1 KKK14451.1 - 0.1 12.7 6.6 0.12 12.5 3.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3246 PF11596.3 KKK14451.1 - 0.2 10.9 10.1 0.32 10.2 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Sigma70_ner PF04546.8 KKK14451.1 - 0.41 10.2 2.3 0.64 9.6 1.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1900 PF08954.6 KKK14452.1 - 3.4e-48 162.6 0.0 1.9e-47 160.1 0.0 2.1 2 1 0 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KKK14452.1 - 4.5e-35 119.0 0.0 8.4e-35 118.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KKK14452.1 - 1.5e-24 84.8 0.7 2.8e-07 30.1 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KKK14452.1 - 0.00093 17.4 0.2 0.2 9.7 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kinesin PF00225.18 KKK14453.1 - 4.5e-105 351.0 0.3 4.5e-105 351.0 0.2 2.1 2 1 0 2 2 2 1 Kinesin motor domain WEMBL PF05701.6 KKK14453.1 - 0.091 11.2 44.7 0.12 10.8 26.5 2.8 2 1 1 3 3 3 0 Weak chloroplast movement under blue light T2SF PF00482.18 KKK14453.1 - 5.8 6.8 7.2 1.5 8.7 0.1 3.0 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F RAI16-like PF10257.4 KKK14454.1 - 3.1e-87 292.7 0.0 4.4e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein MFS_1 PF07690.11 KKK14455.1 - 2.1e-17 62.9 54.4 9.5e-16 57.4 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CBFD_NFYB_HMF PF00808.18 KKK14456.1 - 8.6e-16 57.7 2.3 1.4e-15 57.0 1.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK14456.1 - 2e-07 31.0 0.6 3.1e-07 30.4 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.1 KKK14457.1 - 0.0011 18.5 11.9 0.0018 17.9 8.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KKK14457.1 - 0.74 9.6 6.3 1.2 8.9 4.4 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 KKK14457.1 - 0.98 9.5 12.5 1.7 8.7 8.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.2 KKK14458.1 - 3.6e-33 115.3 0.0 4.4e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK14458.1 - 2.6e-21 76.2 0.0 6.1e-21 75.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK14458.1 - 8.7e-11 41.7 0.0 6e-10 39.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK14458.1 - 2.3e-05 24.1 0.0 4.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 KKK14458.1 - 0.0081 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KKK14458.1 - 0.038 12.7 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase AMP-binding PF00501.23 KKK14459.1 - 4.1e-79 265.9 0.0 5.8e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KKK14459.1 - 3.7e-61 206.1 0.0 6e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KKK14459.1 - 2.5e-27 95.8 5.3 4.4e-24 85.2 2.0 3.0 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.16 KKK14459.1 - 4.7e-15 55.6 0.0 9.2e-09 35.0 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK14459.1 - 1e-14 54.6 2.8 4.9e-11 42.6 1.2 2.6 2 0 0 2 2 2 2 KR domain PP-binding PF00550.20 KKK14459.1 - 1.6e-12 47.4 0.0 4.4e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.1 KKK14459.1 - 7.8e-08 32.3 0.0 1.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KKK14459.1 - 2.2e-07 29.9 0.0 0.0045 15.7 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KKK14459.1 - 1.6e-05 23.9 0.1 0.0068 15.3 0.0 3.2 3 0 0 3 3 3 1 RmlD substrate binding domain AMP-binding_C PF13193.1 KKK14459.1 - 0.00028 21.7 1.5 0.00086 20.2 0.1 2.6 3 0 0 3 3 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 KKK14459.1 - 0.0012 18.8 4.7 0.13 12.2 1.3 4.0 4 1 0 4 4 4 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KKK14459.1 - 0.027 14.2 1.0 0.071 12.9 0.7 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 KKK14459.1 - 0.089 12.2 0.1 0.2 11.0 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Abhydrolase_6 PF12697.2 KKK14460.1 - 8.7e-23 81.3 0.0 1e-22 81.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK14460.1 - 2.1e-09 37.2 0.0 2.6e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK14460.1 - 0.01 15.4 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_2 PF01674.13 KKK14460.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Epimerase PF01370.16 KKK14461.1 - 3.6e-07 29.8 0.1 1.8e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK14461.1 - 5.6e-06 26.4 0.0 1.6e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KKK14461.1 - 1.4e-05 24.4 0.1 0.00011 21.5 0.0 2.2 2 1 1 3 3 3 1 NmrA-like family NAD_binding_4 PF07993.7 KKK14461.1 - 0.00022 20.2 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Sugar_tr PF00083.19 KKK14462.1 - 3.9e-88 296.0 22.0 4.8e-88 295.7 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK14462.1 - 8.4e-16 57.6 27.4 8.4e-16 57.6 19.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1700 PF08006.6 KKK14462.1 - 0.027 13.7 2.8 0.59 9.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Zip PF02535.17 KKK14464.1 - 3.8e-48 164.1 2.1 7.4e-48 163.1 1.5 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Fungal_trans PF04082.13 KKK14465.1 - 6.2e-08 31.8 0.0 1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14465.1 - 1.3e-06 28.2 7.1 2.5e-06 27.2 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KKK14466.1 - 5.5e-36 124.3 0.0 6.6e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK14466.1 - 2.4e-05 23.4 0.0 0.064 12.1 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK14466.1 - 0.00013 20.9 0.1 0.013 14.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 KKK14466.1 - 0.0025 18.1 0.0 0.47 10.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK14466.1 - 0.0032 16.6 0.0 0.0055 15.8 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KKK14466.1 - 0.018 13.7 0.0 0.018 13.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 KKK14466.1 - 0.023 13.7 0.1 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 KKK14466.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.17 KKK14467.1 - 2.1e-12 46.3 0.1 2.6e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Hemerythrin PF01814.18 KKK14468.1 - 2.6e-12 47.0 0.3 3.5e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Dioxygenase_C PF00775.16 KKK14469.1 - 6e-12 45.1 0.3 1e-11 44.4 0.2 1.3 1 0 0 1 1 1 1 Dioxygenase F-box-like PF12937.2 KKK14470.1 - 0.0019 17.8 1.0 0.0019 17.8 0.7 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK14470.1 - 0.03 13.9 1.0 0.066 12.8 0.7 1.5 1 0 0 1 1 1 0 F-box domain DZR PF12773.2 KKK14470.1 - 0.3 10.9 3.1 0.7 9.7 0.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-P11 PF03854.9 KKK14470.1 - 2.9 7.4 5.9 27 4.3 0.6 3.3 3 0 0 3 3 3 0 P-11 zinc finger BTB_2 PF02214.17 KKK14471.1 - 3.5e-07 30.3 0.2 0.0036 17.4 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain GMC_oxred_N PF00732.14 KKK14472.1 - 2e-46 158.4 1.4 2e-46 158.4 0.3 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK14472.1 - 2.5e-30 105.6 0.1 7e-29 100.9 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK14472.1 - 3.5e-07 29.4 1.8 3.3e-06 26.2 1.2 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK14472.1 - 9.6e-07 28.0 6.0 7.7e-06 25.0 4.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK14472.1 - 2.4e-05 24.3 0.2 0.00034 20.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK14472.1 - 3.6e-05 23.7 0.0 0.00021 21.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK14472.1 - 0.0001 21.5 0.1 0.00056 19.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KKK14472.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KKK14472.1 - 0.0032 15.9 0.1 0.0084 14.6 0.0 1.7 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KKK14472.1 - 0.027 13.3 0.1 0.061 12.1 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KKK14472.1 - 0.036 13.1 0.2 0.057 12.4 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase IlvN PF07991.7 KKK14472.1 - 0.055 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Acetyltransf_1 PF00583.19 KKK14473.1 - 7.9e-08 32.2 0.1 5.5e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK14473.1 - 6.3e-07 29.4 0.2 3.1e-06 27.2 0.1 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 KKK14473.1 - 9.6e-06 26.1 0.0 7.4e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK14473.1 - 0.0016 18.2 0.2 0.0077 16.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KKK14473.1 - 0.0017 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 KKK14473.1 - 0.0053 16.8 0.1 0.027 14.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK14473.1 - 0.058 13.1 0.0 9.6 6.0 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein Nol1_Nop2_Fmu PF01189.12 KKK14474.1 - 1.9e-11 43.8 0.0 1.9e-05 24.1 0.0 3.2 2 1 0 2 2 2 2 NOL1/NOP2/sun family DUF2693 PF10902.3 KKK14474.1 - 0.088 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) cNMP_binding PF00027.24 KKK14475.1 - 5.8e-44 147.8 0.0 9.5e-23 79.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.1 KKK14476.1 - 2.2e-11 44.1 0.0 3.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KKK14476.1 - 2.1e-07 30.4 0.0 4.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fork_head PF00250.13 KKK14477.1 - 1.3e-16 60.3 0.1 2.5e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KKK14477.1 - 4.7e-05 23.4 0.0 8.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain Dicty_REP PF05086.7 KKK14477.1 - 2.2 5.9 6.6 3.2 5.3 4.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glutaredoxin PF00462.19 KKK14479.1 - 1.9e-14 53.3 0.2 1.3e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 KKK14479.1 - 0.12 12.5 0.4 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF3336 PF11815.3 KKK14480.1 - 4.7e-39 133.1 0.1 1.4e-38 131.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KKK14480.1 - 1.8e-16 60.7 0.6 3.9e-16 59.6 0.4 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Ribosomal_L6 PF00347.18 KKK14481.1 - 9.6e-24 83.6 3.5 3.3e-11 43.5 0.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PAP1 PF08601.5 KKK14482.1 - 4.7e-97 325.7 11.6 4.7e-97 325.7 8.0 2.4 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 KKK14482.1 - 2.7e-09 36.8 7.5 5.9e-09 35.7 5.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK14482.1 - 0.027 14.2 12.9 0.17 11.7 8.9 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Adeno_PIX PF03955.9 KKK14482.1 - 0.088 13.3 0.4 0.28 11.7 0.2 1.8 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) bZIP_Maf PF03131.12 KKK14482.1 - 0.19 12.0 11.4 0.15 12.4 6.0 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor IncA PF04156.9 KKK14482.1 - 0.49 9.9 3.5 1.3 8.5 1.6 2.1 2 0 0 2 2 2 0 IncA protein XhlA PF10779.4 KKK14482.1 - 1.2 9.1 3.6 0.88 9.5 0.9 2.0 2 0 0 2 2 2 0 Haemolysin XhlA Zwint PF15556.1 KKK14482.1 - 5.6 6.1 11.5 2 7.6 5.3 2.1 2 1 1 3 3 3 0 ZW10 interactor DUF2433 PF10360.4 KKK14483.1 - 1.8e-50 170.6 0.0 3.8e-50 169.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF1793 PF08760.6 KKK14483.1 - 2.3e-43 147.9 0.0 4.6e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Metallophos_2 PF12850.2 KKK14483.1 - 0.009 15.8 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GBA2_N PF12215.3 KKK14483.1 - 0.0096 15.1 0.2 0.0096 15.1 0.1 2.2 3 0 0 3 3 3 1 beta-Glucocerebrosidase 2 N terminal Metallophos PF00149.23 KKK14483.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DUF2360 PF10152.4 KKK14483.1 - 0.02 15.1 0.2 0.42 10.8 0.2 2.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4537 PF15057.1 KKK14484.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF1325 PF07039.6 KKK14484.1 - 0.052 13.1 0.2 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 SGF29 tudor-like domain Fis1_TPR_C PF14853.1 KKK14484.1 - 0.086 12.7 0.3 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TUDOR PF00567.19 KKK14484.1 - 0.087 12.6 0.0 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Tudor domain TP2 PF01254.13 KKK14484.1 - 5.7 7.2 12.5 0.17 12.2 4.2 1.7 2 0 0 2 2 2 0 Nuclear transition protein 2 Pkinase PF00069.20 KKK14487.1 - 3.7e-27 95.1 0.0 5e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14487.1 - 1.1e-22 80.4 0.0 1.6e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KKK14487.1 - 0.00031 19.8 0.0 0.0005 19.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KKK14487.1 - 0.00056 18.9 0.0 0.0015 17.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KKK14487.1 - 0.039 13.2 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family PIP49_C PF12260.3 KKK14487.1 - 0.055 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.15 KKK14487.1 - 0.059 12.9 0.4 0.17 11.4 0.2 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase WaaY PF06176.6 KKK14487.1 - 0.075 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KKK14487.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_3 PF07859.8 KKK14488.1 - 6.6e-21 74.8 0.0 8.5e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK14488.1 - 2.5e-19 69.1 0.0 8.1e-19 67.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KKK14488.1 - 1.3e-06 28.5 0.0 3.5e-06 27.0 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK14488.1 - 6.5e-06 25.9 0.0 9.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KKK14488.1 - 0.0035 16.7 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 KKK14488.1 - 0.018 14.2 0.0 0.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2305 PF10230.4 KKK14488.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) ADH_zinc_N_2 PF13602.1 KKK14489.1 - 3.1e-24 86.2 0.0 5.4e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KKK14489.1 - 9.4e-18 64.0 0.0 1.6e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK14489.1 - 3.3e-05 23.5 0.2 0.00083 19.0 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_3 PF07859.8 KKK14490.1 - 3e-31 108.6 0.0 1.3e-24 87.0 0.1 3.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK14490.1 - 6.1e-16 58.0 0.0 9.3e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KKK14490.1 - 0.013 14.2 0.1 0.29 9.7 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family ParA PF10609.4 KKK14491.1 - 1.7e-31 107.9 0.0 3.6e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KKK14491.1 - 2.5e-17 62.9 0.0 3.7e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KKK14491.1 - 2.8e-09 37.0 0.0 7.6e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KKK14491.1 - 2.5e-05 23.5 0.0 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KKK14491.1 - 0.0013 17.8 0.2 0.0053 15.8 0.3 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KKK14491.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 KKK14491.1 - 0.047 12.8 0.0 0.89 8.6 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1610 PF07754.6 KKK14491.1 - 9.5 6.4 7.2 6.3 7.0 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) AATF-Che1 PF13339.1 KKK14492.1 - 1.6e-31 109.2 4.5 1.6e-31 109.2 3.1 3.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 KKK14492.1 - 3.4e-31 107.1 0.2 3.4e-31 107.1 0.1 2.2 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Sugar_tr PF00083.19 KKK14493.1 - 6.3e-25 87.6 12.0 1.1e-12 47.2 4.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK14493.1 - 5.6e-16 58.1 25.9 5.5e-11 41.7 7.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily APH PF01636.18 KKK14496.1 - 2e-18 67.0 0.0 5.3e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK14496.1 - 7.3e-06 25.1 0.0 0.028 13.5 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KKK14496.1 - 0.00037 20.1 0.0 0.00064 19.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KKK14496.1 - 0.0056 16.0 0.1 0.74 9.1 0.0 2.1 2 0 0 2 2 2 2 RIO1 family DUF4065 PF13274.1 KKK14496.1 - 0.048 14.3 0.1 0.094 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) Pkinase PF00069.20 KKK14496.1 - 0.097 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Inositol_P PF00459.20 KKK14498.1 - 7.6e-70 235.2 0.0 8.6e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.9 KKK14499.1 - 2.6e-41 141.3 0.0 9.5e-37 126.3 0.0 3.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KKK14499.1 - 0.0032 17.0 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KKK14499.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 KKK14499.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.6 KKK14499.1 - 0.049 12.7 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 KKK14499.1 - 0.21 10.4 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Baculo_VP91_N PF08475.5 KKK14499.1 - 0.24 10.7 0.1 0.41 9.9 0.1 1.2 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal PLU-1 PF08429.6 KKK14501.1 - 1.6e-104 349.4 12.8 4.8e-103 344.5 9.0 2.1 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 KKK14501.1 - 8.6e-44 148.4 0.2 1.9e-43 147.3 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KKK14501.1 - 6.1e-27 93.3 0.1 2.3e-26 91.4 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 KKK14501.1 - 1.3e-17 63.5 3.2 3.1e-17 62.3 2.2 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 KKK14501.1 - 2.7e-17 62.1 32.0 8.4e-10 38.1 5.2 3.5 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 KKK14501.1 - 5.1e-17 61.1 1.1 1.3e-16 59.8 0.7 1.7 1 0 0 1 1 1 1 jmjN domain zf-PHD-like PF15446.1 KKK14501.1 - 0.013 14.7 8.8 0.093 12.0 0.7 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Spore_III_AB PF09548.5 KKK14501.1 - 0.68 9.6 2.0 1.5 8.5 0.2 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) zf-RING_2 PF13639.1 KKK14501.1 - 1.1 9.1 23.8 3.6 7.4 5.2 2.7 2 0 0 2 2 2 0 Ring finger domain C1_1 PF00130.17 KKK14501.1 - 5.5 6.7 19.0 0.46 10.2 0.5 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 KKK14502.1 - 1.6e-69 233.9 0.0 2.4e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14502.1 - 1.3e-34 119.4 0.0 2.1e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK14502.1 - 0.00013 21.0 0.1 0.0017 17.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KKK14502.1 - 0.0043 16.1 0.1 0.0086 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Thymidylate_kin PF02223.12 KKK14503.1 - 1.5e-45 154.8 0.0 1.8e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 KKK14503.1 - 0.0027 16.9 0.0 0.0075 15.5 0.0 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 KKK14503.1 - 0.0034 17.3 0.0 0.0045 16.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KKK14503.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NDK PF00334.14 KKK14504.1 - 2.7e-55 185.8 0.0 3.1e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NUFIP1 PF10453.4 KKK14504.1 - 0.068 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) GIY-YIG PF01541.19 KKK14505.1 - 1.9e-07 31.3 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 KKK14505.1 - 0.00018 21.4 5.4 0.0003 20.6 3.7 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.1 KKK14505.1 - 0.062 13.0 7.1 0.069 12.9 2.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TP1 PF02079.11 KKK14505.1 - 5.4 6.8 9.1 12 5.7 0.6 2.5 2 0 0 2 2 2 0 Nuclear transition protein 1 MTHFR PF02219.12 KKK14506.1 - 2.9e-89 298.9 0.0 3.8e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TGT PF01702.13 KKK14507.1 - 6.5e-48 163.0 0.0 8.4e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase FLILHELTA PF10306.4 KKK14508.1 - 6.8e-27 93.3 0.2 3.2e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KKK14508.1 - 0.00073 19.7 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) NMT1 PF09084.6 KKK14509.1 - 4.1e-05 23.2 0.0 0.00025 20.7 0.0 2.0 1 1 1 2 2 2 1 NMT1/THI5 like tRNA-synt_1c PF00749.16 KKK14510.1 - 5.5e-101 337.3 0.0 7.8e-101 336.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KKK14510.1 - 4.8e-44 150.0 0.3 1.1e-43 148.8 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KKK14510.1 - 1.1e-07 32.2 0.2 3.2e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK14510.1 - 0.017 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KKK14510.1 - 0.082 12.9 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 KKK14510.1 - 0.1 11.7 0.3 0.25 10.4 0.1 1.6 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain E1-E2_ATPase PF00122.15 KKK14511.1 - 3.7e-76 255.1 0.2 8.6e-75 250.6 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KKK14511.1 - 9.1e-26 91.6 0.0 2e-25 90.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK14511.1 - 1.5e-13 51.3 0.0 2.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK14511.1 - 2.7e-08 33.1 0.0 6e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK14511.1 - 0.0019 17.8 0.0 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L1 PF00687.16 KKK14512.1 - 6.4e-32 110.6 0.0 1.2e-31 109.7 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Pyr_redox_2 PF07992.9 KKK14513.1 - 1.3e-08 34.9 0.0 9.7e-07 28.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK14513.1 - 0.016 13.7 0.0 0.028 12.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 KKK14513.1 - 0.027 14.4 0.1 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KKK14513.1 - 0.034 12.9 0.0 0.2 10.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK14513.1 - 0.037 13.1 0.0 0.083 11.9 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Glyco_hydro_18 PF00704.23 KKK14514.1 - 1.4e-14 54.3 5.0 3.5e-14 53.0 3.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4611 PF15387.1 KKK14514.1 - 0.017 15.2 1.9 0.036 14.1 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP_sp32 PF07222.7 KKK14514.1 - 0.028 13.6 0.9 0.033 13.3 0.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sporozoite_P67 PF05642.6 KKK14514.1 - 0.048 11.5 0.6 0.059 11.2 0.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1840 PF08895.6 KKK14514.1 - 0.054 13.5 1.3 5.2 7.1 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) PBP1_TM PF14812.1 KKK14514.1 - 1.6 9.0 6.7 2.9 8.2 4.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_31 PF01055.21 KKK14515.1 - 4.4e-146 487.1 6.0 6.5e-146 486.6 4.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 PQ-loop PF04193.9 KKK14515.1 - 2.5e-20 71.7 9.0 4e-14 51.9 0.2 2.8 3 0 0 3 3 3 2 PQ loop repeat Gal_mutarotas_2 PF13802.1 KKK14515.1 - 6.8e-19 67.5 0.2 3.8e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Lipoprotein_18 PF06804.6 KKK14515.1 - 0.04 12.6 0.0 0.095 11.4 0.0 1.6 1 0 0 1 1 1 0 NlpB/DapX lipoprotein MFS_1 PF07690.11 KKK14522.1 - 1.8e-42 145.3 25.2 2.1e-42 145.0 17.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK14522.1 - 8.8e-15 54.2 7.3 1.3e-14 53.6 5.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KKK14522.1 - 0.052 11.5 0.3 0.14 10.1 0.2 1.6 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.14 KKK14523.1 - 1.4e-72 244.7 0.3 1.3e-71 241.5 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KKK14523.1 - 2e-25 89.3 0.0 3.9e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 KKK14523.1 - 0.0055 15.5 0.0 0.02 13.7 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 KKK14523.1 - 0.073 12.9 0.0 0.39 10.5 0.0 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK14523.1 - 0.098 11.0 0.0 0.15 10.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KKK14524.1 - 2.6e-19 70.1 0.0 9.9e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK14524.1 - 4.5e-12 44.9 3.3 1.5e-11 43.2 0.7 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK14524.1 - 2.9e-11 43.2 0.0 5.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK14524.1 - 1.7e-09 37.8 0.0 2.9e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK14524.1 - 1.5e-07 30.7 0.6 2.9e-05 23.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KKK14524.1 - 5e-05 22.3 0.0 0.0012 17.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK14524.1 - 0.00091 19.0 1.5 0.0038 17.0 0.0 2.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KKK14524.1 - 0.0023 16.9 0.1 0.0036 16.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KKK14524.1 - 0.021 13.9 2.2 0.23 10.5 0.0 2.5 3 0 0 3 3 3 0 Thi4 family DUF498 PF04430.9 KKK14524.1 - 0.087 12.3 0.0 8.7 5.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) FAD_binding_2 PF00890.19 KKK14524.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.13 KKK14525.1 - 9.4e-13 47.6 2.4 1.5e-12 46.9 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14525.1 - 3e-07 30.2 5.3 8.4e-07 28.8 3.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KKK14525.1 - 0.013 15.8 4.3 0.013 15.8 3.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK14525.1 - 0.042 14.2 4.1 0.18 12.2 2.9 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1712 PF08217.6 KKK14526.1 - 3.2e-14 52.1 0.0 9.9e-14 50.4 0.0 1.7 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Alg14 PF08660.6 KKK14527.1 - 8.9e-55 185.2 0.0 2e-54 184.1 0.0 1.6 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like adh_short_C2 PF13561.1 KKK14527.1 - 2.9e-23 82.8 0.4 3.8e-23 82.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK14527.1 - 1.9e-21 76.6 0.3 3.5e-21 75.8 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK14527.1 - 1.2e-08 34.8 0.3 1.9e-08 34.1 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF624 PF04854.9 KKK14527.1 - 0.07 12.9 0.2 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Epimerase PF01370.16 KKK14527.1 - 0.13 11.6 0.4 15 4.9 0.0 2.6 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Formyl_trans_N PF00551.14 KKK14528.1 - 3.5e-21 75.5 0.1 2.4e-20 72.8 0.0 2.2 3 0 0 3 3 3 1 Formyl transferase Formyl_trans_C PF02911.13 KKK14528.1 - 0.0011 19.0 0.1 0.0034 17.4 0.1 1.9 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain Ima1_N PF09779.4 KKK14529.1 - 4.7e-45 153.2 1.7 4.7e-45 153.2 1.2 1.7 2 0 0 2 2 2 1 Ima1 N-terminal domain RNHCP PF12647.2 KKK14529.1 - 0.076 12.8 0.7 0.23 11.3 0.5 1.8 1 0 0 1 1 1 0 RNHCP domain Ribonuc_L-PSP PF01042.16 KKK14535.1 - 9.1e-24 83.5 0.0 1.1e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP APH PF01636.18 KKK14537.1 - 3.8e-15 56.2 0.0 8.9e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KKK14537.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 KKK14537.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase TPR_11 PF13414.1 KKK14544.1 - 7.7e-25 86.3 17.4 9.9e-06 25.1 0.0 7.9 8 1 0 8 8 8 5 TPR repeat TPR_19 PF14559.1 KKK14544.1 - 5.3e-19 68.3 17.7 7.1e-07 29.4 0.0 8.4 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 KKK14544.1 - 3.5e-14 51.7 9.6 0.019 15.1 0.0 8.0 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KKK14544.1 - 5.7e-14 52.3 20.2 5.1e-06 27.0 0.0 7.6 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 KKK14544.1 - 2.2e-13 49.9 14.5 0.0039 17.0 0.6 7.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 KKK14544.1 - 4.8e-13 47.9 20.3 0.0063 16.3 0.0 9.2 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KKK14544.1 - 1.4e-12 46.4 8.2 2.5 8.1 0.0 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KKK14544.1 - 2e-12 47.0 6.4 0.0087 16.1 0.0 6.4 6 1 0 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KKK14544.1 - 4.7e-10 38.4 15.5 1.7 8.6 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KKK14544.1 - 5.6e-10 38.9 26.9 0.0026 18.2 1.1 10.2 8 3 3 11 11 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK14544.1 - 1.4e-09 37.1 17.9 0.019 14.5 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KKK14544.1 - 0.00011 22.4 0.3 0.23 11.6 0.0 2.9 2 0 0 2 2 2 2 Alkyl sulfatase dimerisation TPR_6 PF13174.1 KKK14544.1 - 0.00021 21.5 6.5 15 6.3 0.1 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK14544.1 - 0.0029 17.4 3.0 0.059 13.2 0.4 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat FXR1P_C PF12235.3 KKK14544.1 - 0.0099 15.9 9.5 0.022 14.8 6.6 1.5 1 0 0 1 1 1 1 Fragile X-related 1 protein C terminal TPR_20 PF14561.1 KKK14544.1 - 0.013 15.5 6.9 38 4.4 0.1 5.5 3 1 1 5 5 5 0 Tetratricopeptide repeat CDC45 PF02724.9 KKK14544.1 - 0.26 9.2 3.5 0.46 8.4 2.4 1.3 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 KKK14544.1 - 0.28 9.8 7.0 5 5.7 0.1 3.4 2 2 1 3 3 3 0 NMDA receptor-regulated protein 1 DUF3336 PF11815.3 KKK14545.1 - 3.4e-50 169.3 4.5 5.1e-50 168.7 2.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KKK14545.1 - 1e-20 74.5 0.3 5.5e-19 68.9 0.0 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase ABC_tran PF00005.22 KKK14546.1 - 1.4e-07 31.9 0.0 3.7e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Pyr_redox_2 PF07992.9 KKK14546.1 - 0.0021 17.9 0.0 0.0068 16.3 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK14546.1 - 0.0031 17.8 0.0 0.85 10.0 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AAA_29 PF13555.1 KKK14546.1 - 0.0061 16.0 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Pyr_redox_3 PF13738.1 KKK14546.1 - 0.014 15.4 0.0 21 5.0 0.0 3.8 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase G-alpha PF00503.15 KKK14546.1 - 0.059 12.0 0.0 0.094 11.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_21 PF13304.1 KKK14546.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain SAM_2 PF07647.12 KKK14547.1 - 5.4e-09 35.7 0.1 1.1e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KKK14547.1 - 1.1e-05 25.4 0.5 2.4e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DHC_N1 PF08385.7 KKK14547.1 - 0.029 12.7 3.3 0.14 10.5 0.3 2.2 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 RdRP PF05183.7 KKK14548.1 - 1.5e-162 542.3 0.0 1.9e-162 541.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 KKK14548.1 - 0.00045 20.1 0.0 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DNA_binding_2 PF13724.1 KKK14548.1 - 0.015 15.4 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 DNA-binding domain RRM_1 PF00076.17 KKK14548.1 - 0.016 14.8 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans_2 PF11951.3 KKK14549.1 - 0.00029 19.5 1.1 0.00059 18.5 0.1 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain DNA_pol_lambd_f PF10391.4 KKK14550.1 - 2.2e-18 65.5 0.1 4.1e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KKK14550.1 - 4.9e-17 61.3 0.0 1.4e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KKK14550.1 - 6e-16 58.4 0.1 2.1e-15 56.7 0.1 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 KKK14550.1 - 7.6e-11 42.0 0.0 1.2e-09 38.1 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KKK14550.1 - 0.011 16.0 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 Nucleotidyltransferase domain IMS_HHH PF11798.3 KKK14550.1 - 0.12 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif Translin PF01997.11 KKK14551.1 - 3.9e-52 176.7 0.0 4.5e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 KKK14551.1 - 0.05 13.3 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 GMP synthase C terminal domain DUF2336 PF10098.4 KKK14551.1 - 0.056 12.6 1.0 0.084 12.1 0.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) DIM1 PF02966.11 KKK14552.1 - 1.7e-69 231.5 0.3 1.9e-69 231.3 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Fungal_trans PF04082.13 KKK14553.1 - 5.1e-31 107.4 0.0 8.7e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14553.1 - 2.2e-11 43.4 12.6 3.8e-11 42.7 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KKK14553.1 - 0.18 11.7 0.3 0.87 9.5 0.1 2.2 2 0 0 2 2 2 0 Gal4-like dimerisation domain F-box-like PF12937.2 KKK14554.1 - 0.052 13.2 1.0 0.45 10.2 0.9 2.5 2 1 0 2 2 2 0 F-box-like PHD PF00628.24 KKK14556.1 - 1e-11 44.3 7.7 2.2e-11 43.2 5.3 1.6 1 0 0 1 1 1 1 PHD-finger APH PF01636.18 KKK14556.1 - 0.014 15.1 0.0 0.082 12.6 0.0 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 KKK14557.1 - 8.3e-05 21.3 0.0 0.00043 18.9 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2753 PF10952.3 KKK14557.1 - 0.16 11.9 0.2 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2753) GSHPx PF00255.14 KKK14558.1 - 1.5e-38 130.5 0.0 1.9e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KKK14558.1 - 0.003 17.2 0.0 0.0059 16.2 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KKK14558.1 - 0.029 13.8 0.1 0.039 13.4 0.1 1.5 1 1 0 1 1 1 0 Redoxin Pcc1 PF09341.5 KKK14559.1 - 3e-27 94.4 0.0 3.6e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Glycoprotein_B PF00606.13 KKK14560.1 - 0.035 12.1 1.4 0.043 11.8 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF4257 PF14074.1 KKK14560.1 - 0.69 9.6 5.1 3.9 7.1 3.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4257) Phage_holin_1 PF04531.8 KKK14560.1 - 1.7 8.7 4.6 1 9.4 0.5 2.4 1 1 2 3 3 3 0 Bacteriophage holin Synuclein PF01387.12 KKK14560.1 - 5.8 6.8 10.8 18 5.2 7.5 1.8 1 1 1 2 2 2 0 Synuclein DSPn PF14671.1 KKK14561.1 - 6.6e-46 155.8 0.0 1.5e-42 144.9 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KKK14561.1 - 6.8e-16 58.0 0.0 2.6e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KKK14561.1 - 2.5e-06 27.0 0.0 4.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KKK14561.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Fungal_trans_2 PF11951.3 KKK14562.1 - 4.4e-08 32.1 0.5 7.7e-08 31.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14562.1 - 9.9e-08 31.7 8.5 1.8e-07 30.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.1 KKK14564.1 - 2.1e-12 46.6 8.2 3.2e-12 46.0 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK14564.1 - 2.8e-07 30.0 5.9 5.1e-07 29.2 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK14564.1 - 6.3e-06 26.1 5.7 1.5e-05 24.9 3.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK14564.1 - 2e-05 24.5 7.9 4.9e-05 23.3 5.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KKK14564.1 - 0.0002 21.0 3.0 0.00038 20.1 2.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KKK14564.1 - 0.00028 20.5 6.7 0.00046 19.8 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK14564.1 - 0.00088 18.9 4.6 0.0014 18.2 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KKK14564.1 - 0.0032 17.2 2.4 0.0052 16.6 1.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SKG6 PF08693.5 KKK14564.1 - 0.011 14.9 0.2 0.019 14.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KKK14564.1 - 0.031 13.8 0.1 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FANCL_C PF11793.3 KKK14564.1 - 0.038 13.9 2.5 0.038 13.9 1.7 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KKK14564.1 - 0.052 13.1 4.4 0.085 12.4 3.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KKK14564.1 - 0.064 13.3 6.4 0.12 12.4 4.1 1.8 1 1 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 KKK14564.1 - 0.17 11.7 1.4 0.33 10.7 0.9 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 KKK14564.1 - 0.19 11.7 4.7 0.33 10.9 3.2 1.4 1 0 0 1 1 1 0 RING-like domain Elf1 PF05129.8 KKK14564.1 - 0.31 10.7 5.0 7.6 6.3 0.4 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C3HC4_4 PF15227.1 KKK14564.1 - 0.37 10.6 6.4 4.8 7.1 4.4 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KKK14564.1 - 0.66 9.5 4.5 1.4 8.5 3.1 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_Tnp_IS1595 PF12760.2 KKK14564.1 - 0.84 9.5 4.2 0.54 10.1 0.7 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Prok-RING_1 PF14446.1 KKK14564.1 - 1.2 8.8 5.7 0.32 10.7 0.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 XPA_N PF01286.13 KKK14564.1 - 3.8 7.2 7.7 1.2 8.8 0.8 2.3 2 0 0 2 2 2 0 XPA protein N-terminal PHD PF00628.24 KKK14564.1 - 8.2 6.2 7.8 37 4.1 5.6 2.0 1 1 1 2 2 2 0 PHD-finger CNH PF00780.17 KKK14565.1 - 1.3e-73 247.7 0.0 2.1e-73 247.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KKK14565.1 - 1.6e-30 106.3 0.8 3.1e-30 105.3 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KKK14565.1 - 3.7e-12 46.3 0.0 2.3e-11 43.8 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KKK14565.1 - 0.00078 19.6 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 PH domain RabGAP-TBC PF00566.13 KKK14566.1 - 4.6e-47 160.2 0.0 9.2e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 KKK14566.1 - 0.0082 16.2 0.1 0.067 13.3 0.1 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KKK14566.1 - 0.011 15.5 1.2 0.073 12.9 0.1 3.1 4 0 0 4 4 4 0 EF-hand domain GRAM PF02893.15 KKK14566.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 GRAM domain Exo_endo_phos PF03372.18 KKK14567.1 - 4.7e-20 72.5 0.1 5.6e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family adh_short_C2 PF13561.1 KKK14569.1 - 2.4e-18 66.7 0.1 4e-18 66.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK14569.1 - 2.9e-15 56.5 0.7 5.5e-15 55.6 0.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK14569.1 - 5e-05 23.0 0.1 9.3e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK14569.1 - 0.11 11.8 0.2 0.22 10.9 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KKK14569.1 - 0.12 12.4 0.1 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 4HBT_3 PF13622.1 KKK14570.1 - 0.033 13.9 4.5 0.52 9.9 0.8 2.4 2 0 0 2 2 2 0 Thioesterase-like superfamily TPP_enzyme_N PF02776.13 KKK14571.1 - 1.6e-34 118.8 0.5 2.8e-34 118.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ADH_N PF08240.7 KKK14571.1 - 6.3e-26 90.2 0.4 1.4e-25 89.1 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK14571.1 - 1.6e-22 79.4 0.0 6.4e-22 77.4 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.17 KKK14571.1 - 1.8e-20 73.0 0.0 1e-19 70.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KKK14571.1 - 5.7e-18 64.9 0.7 2.6e-17 62.8 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain adh_short_C2 PF13561.1 KKK14571.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF2284 PF10050.4 KKK14571.1 - 0.13 11.8 0.8 1.6 8.2 0.2 2.3 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) EmrE PF13536.1 KKK14572.1 - 0.052 13.7 0.1 0.13 12.5 0.0 1.7 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF401 PF04165.7 KKK14572.1 - 0.14 11.1 0.5 0.19 10.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) APG5 PF04106.7 KKK14580.1 - 7.8e-34 116.8 0.0 1.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 OB_NTP_bind PF07717.11 KKK14581.1 - 2.2e-27 95.1 0.1 5.7e-27 93.8 0.0 1.7 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KKK14581.1 - 7.5e-25 86.9 0.0 2e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK14581.1 - 6.8e-11 41.8 0.0 1.7e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK14581.1 - 3.8e-07 29.7 0.8 7.4e-07 28.8 0.3 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK14581.1 - 1e-05 25.6 0.1 3.7e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KKK14581.1 - 0.00025 20.5 0.3 0.00079 18.9 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 KKK14581.1 - 0.0024 17.7 0.0 0.9 9.3 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KKK14581.1 - 0.004 16.9 1.6 0.0043 16.8 0.2 1.7 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SE PF00437.15 KKK14581.1 - 0.0056 15.6 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KKK14581.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK14581.1 - 0.17 11.4 0.0 0.49 9.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRMT5 PF05185.11 KKK14582.1 - 1.9e-173 577.4 0.0 2.4e-173 577.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Adaptin_N PF01602.15 KKK14588.1 - 5.6e-85 285.6 4.6 6.7e-85 285.3 3.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KKK14588.1 - 3.1e-44 149.5 0.0 7.6e-44 148.2 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KKK14588.1 - 3.1e-19 69.3 0.0 7.3e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain SbcD_C PF12320.3 KKK14588.1 - 0.088 12.8 1.1 0.62 10.1 0.1 2.6 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Ala_racemase_N PF01168.15 KKK14589.1 - 3.5e-41 141.1 0.3 4.2e-41 140.9 0.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain BAF1_ABF1 PF04684.8 KKK14589.1 - 0.087 11.6 0.5 0.11 11.2 0.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor N_NLPC_P60 PF12912.2 KKK14590.1 - 0.0042 17.1 0.8 0.0054 16.8 0.6 1.2 1 0 0 1 1 1 1 NLPC_P60 stabilising domain, N term TPR_11 PF13414.1 KKK14599.1 - 1.1e-10 40.9 0.2 2.7e-05 23.7 0.0 3.6 2 1 2 4 4 4 2 TPR repeat TPR_1 PF00515.23 KKK14599.1 - 3.7e-06 26.3 0.0 0.00026 20.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KKK14599.1 - 8.1e-06 25.6 0.1 0.00035 20.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KKK14599.1 - 1.4e-05 25.3 0.0 3.6e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK14599.1 - 2.2e-05 24.9 0.1 0.45 11.2 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK14599.1 - 3.6e-05 24.0 1.9 0.012 16.1 0.1 3.9 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK14599.1 - 3.8e-05 23.2 0.2 0.0017 18.1 0.0 3.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK14599.1 - 0.00063 19.6 0.1 0.088 12.7 0.0 2.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK14599.1 - 0.00067 19.2 0.0 0.015 15.0 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 KKK14599.1 - 0.0087 16.1 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK14599.1 - 0.032 14.0 0.0 0.99 9.3 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK14599.1 - 0.072 12.9 2.3 0.34 10.7 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpJ PF07201.6 KKK14599.1 - 0.092 12.7 0.2 0.48 10.4 0.0 2.2 3 0 0 3 3 3 0 HrpJ-like domain KorB PF08535.5 KKK14599.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 KorB domain Sigma70_r4 PF04545.11 KKK14599.1 - 0.47 9.7 4.8 7 6.0 1.8 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Adaptin_N PF01602.15 KKK14600.1 - 3.5e-49 167.5 0.0 9.7e-49 166.0 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KKK14600.1 - 1.4e-06 28.4 1.4 0.14 12.4 0.1 3.7 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 KKK14600.1 - 0.0014 19.0 5.7 0.29 11.6 0.0 4.8 4 2 2 6 6 6 2 HEAT-like repeat Cnd1 PF12717.2 KKK14600.1 - 0.003 17.4 2.8 0.16 11.7 0.4 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 KKK14600.1 - 0.011 14.7 0.1 0.063 12.2 0.0 2.2 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 KKK14600.1 - 0.035 14.1 4.7 5.5 7.3 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat RAMP4 PF06624.7 KKK14601.1 - 0.00025 20.5 2.3 0.00054 19.4 1.6 1.6 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Neur_chan_memb PF02932.11 KKK14601.1 - 0.067 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 KKK14602.1 - 0.17 10.4 4.3 0.28 9.7 3.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mitofilin PF09731.4 KKK14602.1 - 1.1 7.8 22.3 0.0042 15.8 8.7 1.8 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DUF763 PF05559.6 KKK14602.1 - 1.6 7.5 5.9 2.2 7.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Asp-B-Hydro_N PF05279.6 KKK14602.1 - 3.1 7.5 21.4 6.5 6.5 14.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region APH PF01636.18 KKK14603.1 - 2.2e-11 43.9 0.0 1.3e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK14603.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Collagen_bind_2 PF12904.2 KKK14603.1 - 0.026 14.2 0.1 2.7 7.8 0.0 2.4 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase Pkinase PF00069.20 KKK14603.1 - 0.14 11.2 0.0 0.51 9.4 0.0 1.7 1 1 1 2 2 2 0 Protein kinase domain Utp21 PF04192.7 KKK14604.1 - 4.8e-77 258.2 0.0 7.2e-77 257.6 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KKK14604.1 - 6.7e-24 82.8 27.6 3.3e-05 23.5 0.0 10.3 12 0 0 12 12 12 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KKK14604.1 - 0.015 13.5 0.1 0.1 10.8 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain XPG_I_2 PF12813.2 KKK14605.1 - 5.3e-76 255.3 0.0 7.6e-76 254.8 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 KKK14605.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 XPG I-region DAGAT PF03982.8 KKK14606.1 - 9.4e-87 290.4 0.0 1.2e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 KKK14606.1 - 0.44 10.1 2.6 0.76 9.3 1.8 1.3 1 0 0 1 1 1 0 Rer1 family G-patch PF01585.18 KKK14607.1 - 1.5e-05 24.6 0.0 0.00022 20.9 0.0 2.5 1 1 0 1 1 1 1 G-patch domain MIP-T3 PF10243.4 KKK14607.1 - 0.1 11.0 45.1 0.13 10.6 31.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SR-25 PF10500.4 KKK14607.1 - 0.13 11.7 45.6 0.21 11.0 31.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC27 PF09507.5 KKK14607.1 - 0.2 10.8 44.5 0.24 10.6 30.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SURF2 PF05477.6 KKK14607.1 - 1.4 7.9 34.3 2.5 7.1 23.8 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Macoilin PF09726.4 KKK14607.1 - 2.7 6.1 27.5 4 5.5 19.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Syja_N PF02383.13 KKK14608.1 - 2.3e-82 276.2 0.0 3.2e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KKK14608.1 - 4e-25 89.2 0.5 9.3e-25 87.9 0.4 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family dCMP_cyt_deam_1 PF00383.17 KKK14610.1 - 9.5e-13 47.6 0.5 1.2e-12 47.4 0.3 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KKK14610.1 - 6.1e-09 35.9 0.4 7.5e-09 35.6 0.3 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KKK14610.1 - 0.06 12.7 0.1 0.06 12.7 0.1 1.3 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Peptidase_M42 PF05343.9 KKK14610.1 - 0.075 11.7 0.1 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase BTB PF00651.26 KKK14612.1 - 0.18 11.7 0.0 0.61 10.0 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain tRNA-synt_2b PF00587.20 KKK14613.1 - 2.1e-21 76.2 0.0 3e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KKK14613.1 - 1.4e-09 37.9 3.0 2.3e-09 37.2 2.1 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GOLGA2L5 PF15070.1 KKK14613.1 - 0.004 15.7 4.1 0.0058 15.1 2.8 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 CENP-F_leu_zip PF10473.4 KKK14613.1 - 0.011 15.5 6.4 0.024 14.5 4.1 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ING PF12998.2 KKK14613.1 - 0.014 15.7 6.1 0.025 14.8 4.2 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding HAUS-augmin3 PF14932.1 KKK14613.1 - 0.014 14.6 3.2 0.021 14.0 2.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Atg14 PF10186.4 KKK14613.1 - 0.025 13.5 3.6 0.042 12.7 2.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 KKK14613.1 - 0.031 14.1 5.5 0.057 13.2 3.8 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4140 PF13600.1 KKK14613.1 - 0.035 14.5 0.5 0.035 14.5 0.3 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KKK14613.1 - 0.042 13.4 7.0 0.069 12.7 4.8 1.2 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 KKK14613.1 - 0.048 12.3 5.6 0.073 11.7 3.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMCO5 PF14992.1 KKK14613.1 - 0.069 12.2 1.6 0.098 11.7 1.1 1.1 1 0 0 1 1 1 0 TMCO5 family FUSC PF04632.7 KKK14613.1 - 0.082 11.3 1.3 0.12 10.8 0.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2968 PF11180.3 KKK14613.1 - 0.14 11.5 8.7 0.27 10.5 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF342 PF03961.8 KKK14613.1 - 0.21 9.9 3.2 0.32 9.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3584 PF12128.3 KKK14613.1 - 0.47 7.7 6.2 0.64 7.2 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_DNA_bd PF12329.3 KKK14613.1 - 0.5 10.2 11.1 1.1 9.0 6.0 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 KKK14613.1 - 0.55 9.2 4.7 0.89 8.5 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 KKK14613.1 - 0.79 9.3 5.6 1.4 8.5 3.9 1.3 1 0 0 1 1 1 0 Mnd1 family DUF904 PF06005.7 KKK14613.1 - 2.2 8.6 7.7 5.6 7.3 5.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 KKK14613.1 - 5.1 6.6 9.7 4.8 6.7 1.2 2.5 1 1 1 2 2 2 0 Septum formation initiator Pkinase PF00069.20 KKK14614.1 - 1.7e-65 220.7 0.0 2.3e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14614.1 - 1.9e-31 109.0 0.0 4.6e-31 107.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK14614.1 - 0.00033 19.7 0.0 0.0007 18.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK14614.1 - 0.0024 16.9 0.0 0.004 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK14614.1 - 0.047 13.4 0.1 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KKK14614.1 - 0.052 12.8 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Fungal_trans_2 PF11951.3 KKK14615.1 - 9.3e-31 106.7 0.7 4.6e-30 104.4 0.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14615.1 - 3.6e-06 26.7 6.7 6.6e-06 25.9 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_1 PF00232.13 KKK14616.1 - 8.6e-145 482.3 1.0 1.2e-144 481.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hyd_65N_2 PF14498.1 KKK14616.1 - 3.5e-58 197.0 0.0 5e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65N PF03636.10 KKK14616.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.19 KKK14617.1 - 1.9e-40 138.8 10.2 2.3e-40 138.5 7.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK14617.1 - 3.4e-14 52.3 15.0 4.5e-14 51.9 10.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_4_9 PF02018.12 KKK14620.1 - 5.5e-10 39.3 3.4 1.7e-09 37.7 2.3 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain Lipase_GDSL_2 PF13472.1 KKK14621.1 - 2.4e-07 31.0 0.1 5.5e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KKK14621.1 - 0.00016 21.5 0.4 0.00045 20.1 0.3 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KKK14621.1 - 0.0018 18.0 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CMD PF02627.15 KKK14622.1 - 0.0045 16.8 7.2 0.13 12.1 0.2 3.4 3 2 0 3 3 3 2 Carboxymuconolactone decarboxylase family MFS_1 PF07690.11 KKK14623.1 - 5.9e-28 97.6 50.0 4.1e-24 84.9 35.0 3.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK14623.1 - 2.5e-16 59.0 28.1 6.1e-15 54.4 19.5 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 KKK14624.1 - 3.7e-32 109.0 4.3 1.9e-09 37.0 0.1 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KKK14624.1 - 4.6e-06 25.6 0.0 0.22 10.1 0.0 3.3 1 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KKK14624.1 - 0.00033 18.9 2.7 0.041 12.0 0.1 2.8 2 2 0 2 2 2 2 Nucleoporin Nup120/160 SGL PF08450.7 KKK14624.1 - 0.075 12.4 1.5 3.6 6.9 0.0 3.1 1 1 2 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region DUF1902 PF08972.6 KKK14624.1 - 0.29 10.7 3.5 2.3 7.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) LSM14 PF12701.2 KKK14625.1 - 1.2e-33 114.7 0.0 2.2e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KKK14625.1 - 3.6e-21 75.6 1.8 3.6e-21 75.6 1.2 1.8 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 KKK14625.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Carn_acyltransf PF00755.15 KKK14626.1 - 4.4e-166 553.4 0.0 4.5e-165 550.1 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP PF00188.21 KKK14627.1 - 1.4e-18 67.5 2.2 1.4e-18 67.5 1.5 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Thioredox_DsbH PF03190.10 KKK14628.1 - 5.4e-72 240.8 0.2 1e-71 239.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KKK14628.1 - 5.7e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KKK14628.1 - 0.054 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_hydro_88 PF07470.8 KKK14628.1 - 0.058 12.4 0.1 1.7 7.5 0.0 2.9 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 DNA_primase_lrg PF04104.9 KKK14629.1 - 9.2e-83 277.4 0.0 1.4e-82 276.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sec23_trunk PF04811.10 KKK14630.1 - 1.1e-80 270.5 0.0 1.6e-80 269.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KKK14630.1 - 8.6e-34 115.0 0.1 1.8e-33 114.0 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KKK14630.1 - 9.7e-30 102.9 0.1 2e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KKK14630.1 - 3.9e-16 58.3 4.5 8.4e-16 57.2 3.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KKK14630.1 - 1.2e-11 44.0 0.0 3.2e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 KKK14631.1 - 9.3e-18 63.4 0.1 1.4e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KKK14631.1 - 4.9e-10 39.4 0.2 7.6e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ADK PF00406.17 KKK14632.1 - 1.3e-34 119.2 0.0 3.3e-34 117.9 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KKK14632.1 - 3.3e-14 52.2 0.0 5.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KKK14632.1 - 9.2e-06 25.9 0.0 2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK14632.1 - 0.0011 19.7 0.0 0.0023 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KKK14632.1 - 0.003 17.4 0.0 0.0078 16.0 0.0 1.7 2 1 0 2 2 2 1 AAA domain Guanylate_kin PF00625.16 KKK14632.1 - 0.18 11.2 0.0 0.71 9.2 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase SNase PF00565.12 KKK14633.1 - 3.1e-19 69.2 0.0 4e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MAP65_ASE1 PF03999.7 KKK14634.1 - 4.3e-54 184.1 23.2 3.2e-30 105.3 1.4 3.0 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.7 KKK14634.1 - 0.21 11.4 4.8 0.59 9.9 1.4 3.1 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus LXG PF04740.7 KKK14634.1 - 0.7 9.6 9.3 0.3 10.8 3.0 2.8 4 0 0 4 4 4 0 LXG domain of WXG superfamily DUF607 PF04678.8 KKK14634.1 - 3.1 7.7 4.7 0.78 9.6 0.0 2.4 3 1 0 3 3 3 0 Protein of unknown function, DUF607 JAB PF01398.16 KKK14635.1 - 2.1e-27 95.1 0.0 3.8e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KKK14635.1 - 9.1e-07 28.4 0.0 1.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RasGEF PF00617.14 KKK14636.1 - 1.3e-63 214.1 0.1 2.3e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KKK14636.1 - 1.5e-27 95.7 0.1 4e-27 94.3 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KKK14636.1 - 2.2e-16 58.9 0.1 4.7e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK14636.1 - 3.9e-14 51.9 0.1 1.4e-13 50.1 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KKK14636.1 - 3.7e-11 42.3 0.1 8.3e-11 41.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KKK14636.1 - 0.0018 18.1 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 WW domain COesterase PF00135.23 KKK14643.1 - 9.9e-46 156.5 0.0 1.3e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK14643.1 - 0.068 12.7 0.0 0.79 9.2 0.0 2.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold CPSase_L_D2 PF02786.12 KKK14644.1 - 2.5e-81 272.0 0.1 4e-81 271.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KKK14644.1 - 1.2e-65 220.6 0.0 2e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KKK14644.1 - 1.2e-35 121.9 0.0 2.5e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KKK14644.1 - 5.8e-30 103.4 0.0 1.9e-29 101.7 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KKK14644.1 - 5.3e-27 94.9 0.0 1e-26 94.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 KKK14644.1 - 5.6e-20 71.8 0.1 1.3e-19 70.6 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KKK14644.1 - 5.4e-19 67.6 2.8 5.4e-19 67.6 1.9 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KKK14644.1 - 3.8e-16 58.7 0.0 1.7e-15 56.6 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK14644.1 - 1.6e-10 40.7 0.0 3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KKK14644.1 - 4e-09 35.9 8.1 2e-06 27.3 0.2 3.4 3 1 1 4 4 4 2 Biotin-lipoyl like ATP-grasp PF02222.17 KKK14644.1 - 1.5e-07 30.9 0.0 2.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KKK14644.1 - 3.8e-06 26.4 0.0 1.8e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 KKK14644.1 - 1.1e-05 25.6 0.1 0.0027 18.0 0.1 3.5 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 KKK14644.1 - 3.5e-05 23.2 0.2 0.002 17.4 0.1 2.5 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 KKK14644.1 - 3.7e-05 23.0 0.1 0.022 13.9 0.1 2.2 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KKK14644.1 - 5.5e-05 23.0 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.4 KKK14644.1 - 0.028 14.1 0.2 0.07 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 KKK14644.1 - 0.15 11.7 1.3 0.49 10.0 0.4 2.2 1 1 1 2 2 2 0 Glycine cleavage H-protein RnfC_N PF13375.1 KKK14644.1 - 0.17 11.6 2.7 1.7 8.3 1.9 2.5 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2569 PF10754.4 KKK14646.1 - 0.038 14.2 0.1 0.04 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) DUF1469 PF07332.6 KKK14646.1 - 0.046 13.4 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF669 PF05037.8 KKK14646.1 - 0.097 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF669) DUF221 PF02714.10 KKK14646.1 - 0.13 11.0 1.0 0.14 10.9 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF221 IlvGEDA_leader PF08046.6 KKK14646.1 - 0.3 10.2 4.0 0.46 9.6 2.8 1.3 1 0 0 1 1 1 0 IlvGEDA operon leader peptide TMEM190 PF15431.1 KKK14646.1 - 0.36 10.7 4.2 0.47 10.3 2.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 190 DUF4381 PF14316.1 KKK14646.1 - 6.4 6.8 7.1 4.6 7.3 3.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Amidase PF01425.16 KKK14647.1 - 3.3e-80 270.0 0.0 4.5e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 KKK14648.1 - 2.4e-07 29.7 0.1 6.2e-07 28.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain ORC4_C PF14629.1 KKK14648.1 - 0.031 13.6 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus AT_hook PF02178.14 KKK14649.1 - 0.0091 15.5 37.6 0.055 13.1 1.3 4.7 4 0 0 4 4 4 3 AT hook motif HMGL-like PF00682.14 KKK14650.1 - 3.1e-22 79.3 0.0 2.5e-21 76.4 0.0 1.9 2 0 0 2 2 2 1 HMGL-like AflR PF08493.5 KKK14651.1 - 1.2e-75 254.0 9.5 1.9e-75 253.4 6.6 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 KKK14651.1 - 9.1e-09 35.0 11.1 1.8e-08 34.1 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4267 PF14087.1 KKK14652.1 - 1.2e-27 95.7 0.5 2e-27 95.0 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) 2OG-FeII_Oxy_2 PF13532.1 KKK14652.1 - 3.5e-16 59.5 0.2 1.9e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KKK14652.1 - 1.3e-06 28.2 5.8 2.3e-06 27.4 4.0 1.4 1 0 0 1 1 1 1 GRF zinc finger DinI PF06183.8 KKK14652.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 DinI-like family DUF3425 PF11905.3 KKK14653.1 - 1.3e-26 93.0 1.8 2.5e-26 92.1 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) NPV_P10 PF05531.7 KKK14653.1 - 0.0032 17.6 1.1 0.0062 16.7 0.8 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein FAM86 PF14904.1 KKK14653.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function GP41 PF00517.12 KKK14653.1 - 0.023 14.2 2.1 0.039 13.5 1.5 1.3 1 0 0 1 1 1 0 Retroviral envelope protein SlyX PF04102.7 KKK14653.1 - 0.03 14.6 3.5 0.065 13.6 2.4 1.6 1 0 0 1 1 1 0 SlyX V_ATPase_I PF01496.14 KKK14653.1 - 0.066 11.0 1.4 0.087 10.6 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL6 PF01763.11 KKK14653.1 - 0.069 11.3 2.6 0.094 10.8 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Atg14 PF10186.4 KKK14653.1 - 0.12 11.3 5.7 0.16 10.8 3.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fmp27_WPPW PF10359.4 KKK14653.1 - 0.13 10.6 3.9 0.19 10.1 2.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF572 PF04502.8 KKK14653.1 - 0.24 10.6 5.9 0.33 10.1 4.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Prominin PF05478.6 KKK14653.1 - 0.28 8.6 2.1 0.37 8.2 1.4 1.1 1 0 0 1 1 1 0 Prominin MbeD_MobD PF04899.7 KKK14653.1 - 0.46 10.4 5.9 0.58 10.0 2.7 2.1 2 0 0 2 2 2 0 MbeD/MobD like Phlebovirus_NSM PF07246.6 KKK14653.1 - 1.7 7.7 5.7 2.5 7.1 3.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ADIP PF11559.3 KKK14653.1 - 2.1 8.2 13.8 3.3 7.5 9.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KKK14653.1 - 2.4 7.7 6.5 3.7 7.1 4.5 1.2 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 KKK14653.1 - 2.6 6.2 7.0 3.6 5.7 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF16 PF01519.11 KKK14653.1 - 5.4 7.2 8.1 8.5 6.6 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 bZIP_1 PF00170.16 KKK14654.1 - 1.2e-09 37.9 15.5 2.1e-09 37.1 10.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK14654.1 - 1.2e-06 28.2 13.9 2.4e-06 27.2 9.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK14654.1 - 0.014 15.7 10.7 0.026 14.8 7.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor SOBP PF15279.1 KKK14654.1 - 0.033 14.5 6.7 0.043 14.1 4.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein IFT57 PF10498.4 KKK14654.1 - 0.073 11.7 4.9 0.11 11.2 3.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DivIC PF04977.10 KKK14654.1 - 0.13 11.7 4.4 0.28 10.6 3.1 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF342 PF03961.8 KKK14654.1 - 0.3 9.4 3.2 0.4 9.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_M20 PF01546.23 KKK14655.1 - 5.8e-09 35.7 0.3 8.7e-09 35.1 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KKK14655.1 - 6.7e-09 35.4 0.2 1.7e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Lzipper-MIP1 PF14389.1 KKK14655.1 - 0.14 12.3 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 PhyH PF05721.8 KKK14656.1 - 8.8e-12 45.5 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KKK14656.1 - 8.2e-09 34.4 0.1 0.017 13.6 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) MFS_1 PF07690.11 KKK14657.1 - 3.9e-29 101.4 36.6 3.9e-29 101.4 25.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 KKK14657.1 - 1.9 8.9 5.4 0.35 11.3 0.2 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) 2OG-FeII_Oxy PF03171.15 KKK14658.1 - 2.5e-15 56.5 0.0 4.5e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KKK14658.1 - 1.3e-11 45.0 0.0 3.9e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fringe PF02434.11 KKK14659.1 - 7.7e-10 38.4 0.2 8.7e-09 34.9 0.1 2.1 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 KKK14659.1 - 0.0037 16.9 0.1 0.0073 16.0 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 KKK14659.1 - 0.01 15.6 0.5 0.021 14.6 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.1 KKK14659.1 - 0.012 15.2 0.4 0.035 13.8 0.3 1.7 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.7 KKK14659.1 - 0.39 10.1 2.0 0.75 9.2 1.4 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Fungal_trans_2 PF11951.3 KKK14660.1 - 1e-54 185.6 1.0 1.3e-54 185.2 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14660.1 - 4.8e-07 29.5 38.1 2.2e-05 24.2 6.6 3.1 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK14661.1 - 4.1e-29 101.4 19.8 4.1e-29 101.4 13.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 KKK14661.1 - 0.035 14.0 0.4 0.78 9.7 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Arginase PF00491.16 KKK14662.1 - 5.4e-09 35.7 0.0 6.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Arginase family DUF4188 PF13826.1 KKK14663.1 - 9.9e-31 106.2 0.3 1.4e-30 105.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dabb PF07876.7 KKK14663.1 - 0.00041 20.7 0.0 0.00071 19.9 0.0 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Dehydratase_hem PF13816.1 KKK14663.1 - 0.09 11.8 0.9 0.86 8.5 0.2 2.0 1 1 1 2 2 2 0 Haem-containing dehydratase DUF3328 PF11807.3 KKK14664.1 - 7.5e-58 195.7 0.5 9e-58 195.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Dynamin_N PF00350.18 KKK14665.1 - 3.6e-33 114.7 0.0 6e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KKK14665.1 - 1.1e-14 53.9 0.2 7.9e-14 51.1 0.1 2.3 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KKK14665.1 - 0.0002 21.2 0.0 0.0011 18.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK14665.1 - 0.0024 18.3 0.0 0.0076 16.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 KKK14665.1 - 0.024 14.6 0.0 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KKK14665.1 - 0.025 14.8 0.1 0.32 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KKK14665.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HSP70 PF00012.15 KKK14666.1 - 2.4e-78 263.5 0.0 7.6e-78 261.9 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein UPRTase PF14681.1 KKK14667.1 - 5.7e-66 221.6 0.0 7e-66 221.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KKK14667.1 - 6.8e-05 22.5 0.0 9.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Hemerythrin PF01814.18 KKK14668.1 - 8.8e-05 22.6 0.0 0.0011 19.1 0.0 2.3 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain CppA_C PF14507.1 KKK14668.1 - 0.11 12.6 0.0 0.41 10.8 0.0 2.0 2 1 0 2 2 2 0 CppA C-terminal CDC45 PF02724.9 KKK14669.1 - 2.5e-237 788.8 12.9 1.9e-216 719.9 0.0 3.1 2 1 1 3 3 3 2 CDC45-like protein SDA1 PF05285.7 KKK14669.1 - 0.11 11.7 28.8 0.58 9.3 5.9 2.2 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.7 KKK14669.1 - 0.12 10.3 28.3 0.4 8.5 7.8 2.1 2 0 0 2 2 2 0 Nop14-like family AIF-MLS PF14962.1 KKK14669.1 - 0.16 11.5 9.3 0.28 10.8 6.5 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence MIP-T3 PF10243.4 KKK14669.1 - 0.77 8.1 34.8 0.09 11.2 4.5 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 BUD22 PF09073.5 KKK14669.1 - 2.7 6.9 42.8 0.2 10.6 12.8 2.2 2 0 0 2 2 2 0 BUD22 Daxx PF03344.10 KKK14669.1 - 3.2 6.1 31.4 0.95 7.8 5.2 2.1 2 0 0 2 2 2 0 Daxx Family zf-C2H2 PF00096.21 KKK14670.1 - 1.3e-07 31.5 14.9 0.0014 18.8 1.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK14670.1 - 5.3e-07 29.6 25.8 1.1e-05 25.4 2.3 4.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK14670.1 - 0.014 15.7 1.6 0.014 15.7 1.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK14670.1 - 2.8 8.1 5.2 0.41 10.8 0.2 2.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding LSM PF01423.17 KKK14671.1 - 5.9e-13 48.1 0.1 9.3e-13 47.5 0.1 1.3 1 0 0 1 1 1 1 LSM domain zf-H2C2_2 PF13465.1 KKK14672.1 - 0.097 13.0 0.9 0.097 13.0 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK14672.1 - 0.13 12.7 0.8 0.13 12.7 0.6 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Asp PF00026.18 KKK14673.1 - 3.7e-70 236.7 7.3 3.7e-70 236.7 5.0 1.8 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK14673.1 - 7e-12 45.6 0.5 7e-12 45.6 0.3 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KKK14673.1 - 2.4e-07 31.1 0.1 0.037 14.5 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KKK14673.1 - 0.0067 15.9 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal SAP PF02037.22 KKK14674.1 - 2.3e-08 33.3 0.4 4.3e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 SAP domain Rad52_Rad22 PF04098.10 KKK14675.1 - 3.2e-60 202.3 0.0 4.6e-60 201.8 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UBA PF00627.26 KKK14676.1 - 5.4e-06 26.0 0.5 1.1e-05 25.1 0.0 1.8 2 0 0 2 2 1 1 UBA/TS-N domain UBX PF00789.15 KKK14676.1 - 0.012 15.6 0.1 0.1 12.6 0.0 2.5 2 2 0 2 2 2 0 UBX domain zf-C2H2_2 PF12756.2 KKK14676.1 - 0.035 14.2 0.2 0.08 13.0 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GATA PF00320.22 KKK14676.1 - 0.037 13.3 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger DUF3595 PF12166.3 KKK14676.1 - 0.07 11.9 0.5 0.089 11.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) zf-C2H2 PF00096.21 KKK14676.1 - 0.11 12.8 0.9 0.19 12.1 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Crystallin PF00525.13 KKK14676.1 - 0.13 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal zf-C2H2_jaz PF12171.3 KKK14676.1 - 0.18 12.0 1.5 0.31 11.2 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Ycf1 PF05758.7 KKK14676.1 - 0.46 8.1 9.2 0.49 8.0 6.3 1.2 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 KKK14676.1 - 1 8.7 39.1 1.4 8.2 27.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rtf2 PF04641.7 KKK14676.1 - 1.1 8.3 20.3 1.7 7.8 14.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Hex_IIIa PF02455.11 KKK14676.1 - 2.2 6.8 12.6 3.1 6.3 8.8 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) CpXC PF14353.1 KKK14676.1 - 3.7 7.5 11.2 0.3 11.0 2.6 2.2 1 1 1 2 2 2 0 CpXC protein SOBP PF15279.1 KKK14676.1 - 3.9 7.7 8.3 4.8 7.4 5.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.5 KKK14676.1 - 5.5 5.2 4.8 6.5 5.0 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF342 PF03961.8 KKK14676.1 - 6.5 5.0 14.9 9.4 4.5 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Motile_Sperm PF00635.21 KKK14677.1 - 1.5e-23 82.4 0.7 3.5e-23 81.3 0.4 1.6 1 1 1 2 2 2 1 MSP (Major sperm protein) domain DUF2077 PF09850.4 KKK14677.1 - 0.065 12.6 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Lipid_DES PF08557.5 KKK14678.1 - 8.7e-20 69.6 0.2 8.7e-20 69.6 0.1 1.9 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.19 KKK14678.1 - 1.1e-17 64.3 17.1 1.7e-16 60.4 11.8 2.6 1 1 0 1 1 1 1 Fatty acid desaturase Peptidase_M24 PF00557.19 KKK14679.1 - 3.8e-38 131.1 0.1 5.7e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 NST1 PF13945.1 KKK14679.1 - 0.055 13.5 3.0 0.084 12.9 2.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Tom37_C PF11801.3 KKK14679.1 - 4.5 7.1 5.1 7.7 6.3 3.5 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain SAP25 PF15476.1 KKK14680.1 - 0.0099 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase complex subunit SAP25 FCH PF00611.18 KKK14680.1 - 0.13 12.4 0.2 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Aa_trans PF01490.13 KKK14681.1 - 7.5e-72 242.0 31.2 9.3e-72 241.7 21.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Vfa1 PF08432.5 KKK14682.1 - 5e-65 218.9 18.4 5.6e-65 218.7 12.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 KKK14682.1 - 0.00027 19.1 13.9 0.00029 19.0 9.6 1.0 1 0 0 1 1 1 1 CDC45-like protein CENP-T PF15511.1 KKK14682.1 - 0.00065 19.0 6.7 0.00075 18.8 4.6 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T BORG_CEP PF14957.1 KKK14682.1 - 0.1 13.5 7.1 0.2 12.5 4.9 1.4 1 0 0 1 1 1 0 Cdc42 effector RR_TM4-6 PF06459.7 KKK14682.1 - 0.19 11.6 14.3 0.25 11.1 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 KKK14682.1 - 0.21 9.2 12.2 0.23 9.1 8.4 1.0 1 0 0 1 1 1 0 Ycf1 NPR3 PF03666.8 KKK14682.1 - 0.22 9.9 8.8 0.28 9.6 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.12 KKK14682.1 - 0.28 10.9 5.7 0.34 10.6 4.0 1.2 1 0 0 1 1 1 0 DDHD domain HCMV_UL139 PF12507.3 KKK14682.1 - 0.31 11.2 10.1 0.68 10.1 6.9 1.7 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein GAGA_bind PF06217.7 KKK14682.1 - 0.49 10.3 9.8 0.59 10.0 6.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2201_N PF13203.1 KKK14682.1 - 0.58 9.2 7.3 0.69 9.0 5.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Cupin_8 PF13621.1 KKK14682.1 - 0.73 9.2 5.5 0.85 9.0 3.8 1.2 1 0 0 1 1 1 0 Cupin-like domain NARP1 PF12569.3 KKK14682.1 - 1.7 7.2 17.3 2 7.0 12.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PBP_sp32 PF07222.7 KKK14682.1 - 1.8 7.6 9.5 2.3 7.3 6.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Hid1 PF12722.2 KKK14682.1 - 1.9 6.0 11.1 2.2 5.8 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3449 PF11931.3 KKK14682.1 - 2.2 7.7 15.9 3.4 7.1 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF1510 PF07423.6 KKK14682.1 - 3 7.1 24.8 4.1 6.7 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2252 PF10009.4 KKK14682.1 - 3.4 6.4 10.0 4.5 6.0 6.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF4407 PF14362.1 KKK14682.1 - 3.8 6.3 9.2 4.9 6.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) U79_P34 PF03064.11 KKK14682.1 - 6.1 6.2 17.0 8.4 5.8 11.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FAM60A PF15396.1 KKK14682.1 - 6.6 6.4 18.9 3.8 7.2 8.8 2.1 2 0 0 2 2 2 0 Protein Family FAM60A MIP-T3 PF10243.4 KKK14682.1 - 7 4.9 27.8 8.6 4.7 19.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UPF0560 PF10577.4 KKK14682.1 - 7.5 4.6 10.3 9 4.4 7.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pkinase PF00069.20 KKK14683.1 - 1.8e-27 96.1 0.0 2.3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14683.1 - 8.4e-10 38.1 0.0 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FMN_dh PF01070.13 KKK14684.1 - 1.5e-96 323.3 0.7 1.7e-61 208.0 0.1 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KKK14684.1 - 8.1e-19 67.2 0.0 1.7e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KKK14684.1 - 5.1e-05 22.3 0.0 8.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KKK14684.1 - 0.0026 16.8 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 KKK14684.1 - 0.009 14.9 0.1 0.024 13.5 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KKK14684.1 - 0.029 13.5 0.2 6.3 5.8 0.0 2.2 1 1 1 2 2 2 0 Nitronate monooxygenase TatD_DNase PF01026.16 KKK14685.1 - 8.7e-51 172.5 0.0 1e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Y_phosphatase2 PF03162.8 KKK14686.1 - 7.6e-49 165.2 0.0 1e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KKK14686.1 - 1.6e-10 41.5 0.0 1.4e-09 38.4 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KKK14686.1 - 0.00071 19.1 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KKK14686.1 - 0.0026 17.1 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KKK14686.1 - 0.0033 17.4 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 KKK14686.1 - 0.081 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) 4HBT PF03061.17 KKK14687.1 - 0.007 16.4 0.1 4.6 7.4 0.0 2.6 2 0 0 2 2 2 2 Thioesterase superfamily tRNA-synt_2 PF00152.15 KKK14689.1 - 2e-68 230.6 0.1 4.4e-68 229.5 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KKK14689.1 - 9.7e-18 64.0 0.0 1.4e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 KKK14689.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KKK14689.1 - 0.0034 16.5 0.7 1.4 8.0 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Acetyltransf_6 PF13480.1 KKK14689.1 - 0.011 15.7 0.6 0.052 13.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Tubulin PF00091.20 KKK14691.1 - 1.4e-70 237.4 0.0 2e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KKK14691.1 - 7e-49 165.0 0.1 1.7e-48 163.8 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KKK14691.1 - 0.002 17.6 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.2 KKK14692.1 - 7.7e-37 125.2 0.0 1.6e-14 53.4 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KKK14692.1 - 3.4e-11 43.1 0.0 8.1e-06 25.8 0.0 3.9 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KKK14692.1 - 4.7e-09 34.9 0.0 0.0016 17.5 0.0 5.2 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.1 KKK14692.1 - 1.4e-07 30.7 0.2 0.81 9.7 0.0 5.8 6 0 0 6 6 6 1 EF-hand domain EF-hand_8 PF13833.1 KKK14692.1 - 8.7e-05 22.0 0.1 0.0082 15.7 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain pair UBA PF00627.26 KKK14692.1 - 0.00022 20.9 0.0 0.00046 19.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Myosin_tail_1 PF01576.14 KKK14692.1 - 0.051 11.3 20.0 0.072 10.8 13.9 1.1 1 0 0 1 1 1 0 Myosin tail U3_assoc_6 PF08640.6 KKK14692.1 - 0.16 11.7 0.9 0.33 10.7 0.7 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 FUSC PF04632.7 KKK14692.1 - 0.28 9.5 3.2 0.48 8.7 2.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.7 KKK14692.1 - 0.46 10.2 20.0 4.9 6.9 13.9 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein THOC7 PF05615.8 KKK14692.1 - 0.55 10.4 12.0 4.3 7.5 3.3 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 TMF_TATA_bd PF12325.3 KKK14692.1 - 1.6 8.5 13.8 2.6 7.7 3.7 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mod_r PF07200.8 KKK14692.1 - 2.3 8.1 14.5 1 9.2 8.0 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 KKK14692.1 - 4.2 6.5 20.0 2.3 7.3 5.3 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 KKK14692.1 - 8 5.0 20.8 0.12 11.0 5.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Glyco_transf_8 PF01501.15 KKK14703.1 - 1.9e-33 115.8 0.0 3.3e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 KKK14703.1 - 0.083 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 KKK14703.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Abhydrolase_6 PF12697.2 KKK14704.1 - 3.8e-26 92.3 0.0 1.7e-25 90.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK14704.1 - 6.2e-11 42.3 0.0 5e-10 39.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK14704.1 - 3.4e-10 39.8 0.0 2e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KKK14704.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 KKK14704.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 KKK14704.1 - 0.11 11.9 0.0 10 5.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase VHS PF00790.14 KKK14705.1 - 1.7e-31 108.7 0.6 6.7e-24 84.1 0.0 2.4 2 0 0 2 2 2 2 VHS domain SH3_1 PF00018.23 KKK14705.1 - 8.5e-16 57.0 0.0 1.8e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK14705.1 - 1.4e-15 56.5 0.1 2.6e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KKK14705.1 - 3e-14 52.2 0.0 5.8e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 KKK14705.1 - 0.042 13.4 1.9 0.12 11.9 1.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Antimicrobial11 PF08106.6 KKK14705.1 - 0.36 10.7 7.5 0.88 9.4 0.1 3.0 2 0 0 2 2 2 0 Formaecin family UCH_1 PF13423.1 KKK14706.1 - 5.8e-67 226.2 0.5 7.5e-67 225.8 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KKK14706.1 - 4.4e-22 79.1 0.0 1.1e-21 77.8 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KKK14706.1 - 2.6e-09 36.5 0.2 5e-08 32.3 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase KH_1 PF00013.24 KKK14707.1 - 5.4e-92 301.3 18.6 8.9e-12 44.4 0.3 13.7 13 1 0 13 13 13 9 KH domain KH_3 PF13014.1 KKK14707.1 - 1.1e-66 219.6 21.8 3.1e-09 36.2 0.7 13.5 14 1 0 14 14 14 10 KH domain KH_2 PF07650.12 KKK14707.1 - 7.1e-11 41.5 25.2 0.0058 16.1 0.3 7.9 6 1 1 7 7 7 4 KH domain SLS PF14611.1 KKK14707.1 - 5.9e-10 38.9 0.1 0.018 14.4 0.0 7.1 6 3 1 7 7 7 2 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.1 KKK14707.1 - 0.46 10.3 9.2 25 4.7 0.2 5.8 7 0 0 7 7 7 0 NusA-like KH domain Pkinase PF00069.20 KKK14708.1 - 1.5e-70 237.3 0.0 2.5e-70 236.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14708.1 - 8.5e-45 152.8 0.0 1.4e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KKK14708.1 - 2e-21 76.1 0.1 9.2e-21 74.0 0.0 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KKK14708.1 - 1.5e-06 27.4 0.0 2.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 KKK14708.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.18 KKK14708.1 - 0.8 9.3 9.2 0.21 11.2 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family AMP-binding PF00501.23 KKK14709.1 - 2.1e-92 309.7 0.1 2.6e-92 309.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK14709.1 - 1.5e-20 73.8 3.3 1.8e-19 70.4 0.2 2.9 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain FGGY_C PF02782.11 KKK14711.1 - 3.1e-74 248.8 0.8 5.8e-74 248.0 0.6 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KKK14711.1 - 3.8e-60 203.2 0.0 5e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KKK14711.1 - 0.0037 16.6 0.6 0.079 12.2 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.13 KKK14712.1 - 1.4e-65 220.7 0.1 2.7e-65 219.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KKK14712.1 - 1.2e-42 145.2 0.0 3.9e-42 143.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KKK14712.1 - 6e-06 27.0 0.0 1.9e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK14712.1 - 7.7e-06 26.0 0.1 3.7e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KKK14712.1 - 9.3e-06 25.4 0.0 3.6e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KKK14712.1 - 6.7e-05 21.7 1.8 0.00011 21.0 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 KKK14712.1 - 0.0002 20.4 0.0 0.00056 19.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KKK14712.1 - 0.00043 20.4 2.9 0.011 15.8 0.2 3.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KKK14712.1 - 0.0011 18.8 0.1 0.006 16.4 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 KKK14712.1 - 0.0016 18.1 0.3 0.0047 16.6 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KKK14712.1 - 0.0023 17.3 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KKK14712.1 - 0.0072 15.7 4.0 0.083 12.2 0.3 2.7 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KKK14712.1 - 0.008 15.3 1.7 0.022 13.8 0.2 2.3 2 1 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 KKK14712.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KKK14712.1 - 0.013 15.3 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KKK14712.1 - 0.014 15.0 0.5 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KKK14712.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK14712.1 - 0.02 14.0 0.2 0.04 13.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KKK14712.1 - 0.048 13.9 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KKK14712.1 - 0.048 12.7 0.5 1.3 8.0 0.0 2.7 3 0 0 3 3 3 0 KaiC DUF815 PF05673.8 KKK14712.1 - 0.05 12.5 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTP_transferase PF00483.18 KKK14714.1 - 6.6e-48 163.1 0.0 1.3e-47 162.2 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KKK14714.1 - 3.3e-16 57.9 14.8 7.7e-10 37.8 2.1 4.3 2 1 3 5 5 5 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KKK14714.1 - 6.6e-11 42.5 0.0 1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KKK14714.1 - 9.7e-07 28.2 2.4 9.7e-07 28.2 1.7 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 KKK14714.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fungal_trans PF04082.13 KKK14715.1 - 1.5e-22 79.7 0.6 2.1e-22 79.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14715.1 - 0.062 13.2 4.9 0.14 12.1 3.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.17 KKK14716.1 - 3.8e-52 176.6 2.5 4.4e-52 176.4 1.7 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KKK14716.1 - 0.00045 19.7 0.1 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KKK14716.1 - 0.00066 19.5 0.0 0.00095 18.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) LVIVD PF08309.6 KKK14717.1 - 1e-12 46.8 1.7 0.11 11.4 0.0 5.4 5 0 0 5 5 5 5 LVIVD repeat Brr6_like_C_C PF10104.4 KKK14718.1 - 5.4e-43 145.7 0.1 7.1e-43 145.3 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Corona_RPol_N PF06478.8 KKK14718.1 - 0.03 13.0 0.0 0.043 12.5 0.0 1.1 1 0 0 1 1 1 0 Coronavirus RPol N-terminus DUF1811 PF08838.5 KKK14719.1 - 0.019 14.9 0.3 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) Bud13 PF09736.4 KKK14720.1 - 2e-34 118.9 5.7 3.3e-33 114.9 0.5 2.8 2 2 1 3 3 3 2 Pre-mRNA-splicing factor of RES complex DUF162 PF02589.10 KKK14720.1 - 3.2 7.2 6.5 0.73 9.3 1.7 1.8 2 0 0 2 2 2 0 Uncharacterised ACR, YkgG family COG1556 DNA_binding_1 PF01035.15 KKK14721.1 - 1.6e-20 72.5 0.0 2.3e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HsbA PF12296.3 KKK14722.1 - 2.3e-20 72.6 5.0 2.3e-20 72.6 3.4 2.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Utp12 PF04003.7 KKK14723.1 - 8.1e-21 73.9 0.0 1.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Frataxin_Cyay PF01491.11 KKK14724.1 - 2.6e-35 120.4 0.0 3.4e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain GKAP PF03359.8 KKK14724.1 - 0.072 12.6 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein HAUS4 PF14735.1 KKK14725.1 - 0.0033 16.7 1.3 0.013 14.8 0.9 1.9 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 DinB_2 PF12867.2 KKK14725.1 - 0.16 12.3 8.4 0.77 10.1 0.4 2.9 2 1 1 3 3 3 0 DinB superfamily Bromodomain PF00439.20 KKK14726.1 - 3.4e-37 126.2 1.6 1.2e-18 66.7 0.1 3.1 3 0 0 3 3 3 2 Bromodomain Angiomotin_C PF12240.3 KKK14726.1 - 0.099 12.1 7.2 0.24 10.8 5.0 1.6 1 0 0 1 1 1 0 Angiomotin C terminal DUF3573 PF12097.3 KKK14726.1 - 1 7.9 4.7 1.7 7.1 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) AKAP7_NLS PF10469.4 KKK14727.1 - 7.4e-15 55.2 0.0 1.9e-13 50.6 0.0 2.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain zf-CSL PF05207.8 KKK14728.1 - 3.2e-25 87.3 0.6 3.8e-25 87.1 0.4 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 KKK14728.1 - 0.012 15.5 0.2 0.021 14.7 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Prok-RING_1 PF14446.1 KKK14728.1 - 1 9.1 4.1 3.2 7.5 2.9 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Pyridoxal_deC PF00282.14 KKK14729.1 - 2.1e-14 52.7 0.0 1.3e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KKK14729.1 - 0.021 13.5 0.0 0.077 11.7 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 KKK14729.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II HMGL-like PF00682.14 KKK14730.1 - 3.6e-71 239.5 0.4 5.2e-71 239.0 0.3 1.2 1 0 0 1 1 1 1 HMGL-like TMCO5 PF14992.1 KKK14730.1 - 0.0022 17.1 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 TMCO5 family Lumazine_bd PF12870.2 KKK14730.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Lumazine-binding domain DUF4448 PF14610.1 KKK14731.1 - 1.1e-40 139.2 0.0 1.8e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) PTH2 PF01981.11 KKK14733.1 - 5.5e-43 145.3 0.4 8.6e-43 144.7 0.3 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BSP_II PF05432.6 KKK14733.1 - 0.00092 18.5 4.1 0.0012 18.1 2.8 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 KKK14733.1 - 0.8 8.8 4.2 1.1 8.4 2.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region SART-1 PF03343.8 KKK14734.1 - 5.1e-172 573.4 47.0 5.9e-172 573.2 32.6 1.0 1 0 0 1 1 1 1 SART-1 family DUF2330 PF10092.4 KKK14735.1 - 0.029 13.2 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Aminotran_1_2 PF00155.16 KKK14736.1 - 2.1e-91 306.6 0.0 2.4e-91 306.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sec6 PF06046.8 KKK14737.1 - 4.6e-152 507.0 3.4 4.6e-152 507.0 2.4 2.5 2 1 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.7 KKK14737.1 - 0.0014 17.5 10.7 0.0041 15.9 1.8 2.3 2 0 0 2 2 2 2 Vps53-like, N-terminal Cortex-I_coil PF09304.5 KKK14737.1 - 0.21 11.6 7.1 0.37 10.8 3.6 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil NPV_P10 PF05531.7 KKK14737.1 - 0.46 10.7 3.7 9.3 6.5 0.6 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF572 PF04502.8 KKK14737.1 - 4.5 6.3 7.0 7.5 5.6 4.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_L30 PF00327.15 KKK14738.1 - 7.9e-17 60.5 0.2 1.1e-16 60.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF3445 PF11927.3 KKK14739.1 - 1.4e-12 47.5 0.2 2e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF1227 PF06777.6 KKK14740.1 - 1.1e-62 210.0 0.6 2.6e-62 208.8 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KKK14740.1 - 3.4e-52 176.3 0.2 6.4e-52 175.4 0.2 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KKK14740.1 - 7e-45 152.9 0.0 1.7e-44 151.7 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 KKK14740.1 - 0.00043 19.1 0.0 0.0018 17.1 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KKK14740.1 - 0.0015 18.0 0.0 0.17 11.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 KKK14740.1 - 0.0016 18.0 0.0 0.004 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KKK14740.1 - 0.0046 16.8 0.0 0.019 14.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KKK14740.1 - 0.028 14.5 0.9 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 KKK14740.1 - 0.077 11.9 0.0 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Stomoxyn PF11585.3 KKK14740.1 - 0.21 11.4 0.2 0.77 9.6 0.1 1.9 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn LCM PF04072.9 KKK14741.1 - 1.3e-22 80.2 0.0 2.9e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase C1_1 PF00130.17 KKK14741.1 - 0.035 13.8 1.1 0.074 12.7 0.7 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SUN PF03856.8 KKK14742.1 - 2.6e-81 272.6 13.8 4.9e-81 271.7 9.6 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) TT_ORF1 PF02956.9 KKK14742.1 - 0.78 8.1 10.5 1.2 7.5 7.2 1.2 1 0 0 1 1 1 0 TT viral orf 1 Dicty_REP PF05086.7 KKK14742.1 - 2.4 5.8 20.7 3.4 5.2 14.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ist1 PF03398.9 KKK14743.1 - 1.3e-49 167.8 0.3 8e-24 83.9 1.0 2.1 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway TraI PF07057.6 KKK14743.1 - 0.049 13.6 0.3 1 9.3 0.1 2.2 2 0 0 2 2 2 0 DNA helicase TraI Glyco_transf_22 PF03901.12 KKK14744.1 - 3.1e-62 210.9 17.0 3.7e-55 187.6 10.1 2.9 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.1 KKK14744.1 - 5.9 6.7 18.1 0.097 12.5 5.3 2.4 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Gar1 PF04410.9 KKK14745.1 - 5.4e-47 159.1 0.1 5.4e-47 159.1 0.1 2.7 4 0 0 4 4 4 1 Gar1/Naf1 RNA binding region API5 PF05918.6 KKK14745.1 - 4.5 5.6 6.7 8.4 4.7 4.6 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PRP3 PF08572.5 KKK14746.1 - 8.6e-73 244.4 5.5 1.6e-72 243.5 3.8 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KKK14746.1 - 2.9e-40 136.8 0.1 6.5e-40 135.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 KKK14747.1 - 4.6e-85 285.2 0.3 1.1e-84 284.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KKK14747.1 - 1.1e-62 210.9 0.0 2.9e-62 209.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KKK14747.1 - 7.8e-34 116.6 0.0 1.2e-32 112.8 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KKK14747.1 - 7.6e-23 81.2 6.9 2.2e-16 60.0 0.0 2.9 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KKK14747.1 - 6.7e-16 57.9 0.0 3.4e-15 55.7 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 FA_desaturase PF00487.19 KKK14748.1 - 2.7e-11 43.3 26.3 2.7e-11 43.3 18.2 1.7 1 1 1 2 2 2 1 Fatty acid desaturase ABC_membrane PF00664.18 KKK14748.1 - 0.035 13.5 0.1 0.035 13.5 0.1 1.7 2 0 0 2 2 2 0 ABC transporter transmembrane region MFS_1 PF07690.11 KKK14749.1 - 9.1e-15 54.2 37.0 9.1e-15 54.2 25.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily SAICAR_synt PF01259.13 KKK14750.1 - 4.3e-44 150.4 0.0 5e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase FAD_binding_3 PF01494.14 KKK14751.1 - 1.2e-83 281.0 0.1 1.5e-83 280.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK14751.1 - 2.3e-05 23.4 1.1 4.7e-05 22.4 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK14751.1 - 2.7e-05 24.1 0.2 0.00021 21.2 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK14751.1 - 8.5e-05 21.7 0.1 0.00015 20.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KKK14751.1 - 0.0001 21.3 0.1 0.00018 20.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KKK14751.1 - 0.00037 19.1 0.2 0.0007 18.1 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KKK14751.1 - 0.0019 17.1 0.1 0.0036 16.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KKK14751.1 - 0.0024 16.5 0.0 0.0044 15.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KKK14751.1 - 0.0038 17.1 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK14751.1 - 0.0065 16.8 1.8 0.031 14.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KKK14751.1 - 0.012 15.2 0.4 0.053 13.1 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 KKK14751.1 - 0.018 13.8 0.0 0.046 12.5 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase Peptidase_C41 PF05417.6 KKK14751.1 - 0.019 14.4 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Hepatitis E cysteine protease Pyr_redox_3 PF13738.1 KKK14751.1 - 0.026 14.6 0.1 0.059 13.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK14751.1 - 0.069 12.9 1.6 0.098 12.4 0.1 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Glycogen_syn PF05693.8 KKK14752.1 - 0 1129.1 0.0 0 1128.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_4_4 PF13579.1 KKK14752.1 - 5.4e-07 29.8 0.2 1.1e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 KKK14752.1 - 3.9e-05 23.1 0.0 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 APC8 PF04049.8 KKK14753.1 - 1.9e-54 183.2 0.1 1.5e-53 180.3 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KKK14753.1 - 4.6e-24 82.9 3.0 0.00015 21.2 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 KKK14753.1 - 8.6e-20 70.1 16.0 3.4e-07 29.7 0.1 7.1 6 2 1 7 7 7 4 TPR repeat TPR_2 PF07719.12 KKK14753.1 - 5e-18 63.4 18.0 0.065 13.1 2.0 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KKK14753.1 - 7e-17 61.6 11.8 5.1e-05 23.8 0.0 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK14753.1 - 8.4e-16 56.4 8.5 0.0003 20.3 0.0 8.1 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KKK14753.1 - 3.4e-11 42.7 14.0 0.0055 17.2 0.0 9.2 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK14753.1 - 2.5e-10 40.5 5.9 0.69 10.2 0.0 7.1 6 1 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KKK14753.1 - 9e-10 38.5 11.1 0.26 11.4 0.1 5.7 7 1 0 7 7 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KKK14753.1 - 1.2e-09 37.9 6.2 0.00053 19.7 0.1 5.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK14753.1 - 5.7e-08 32.3 6.4 2.2 8.6 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK14753.1 - 4.2e-07 29.7 25.8 0.032 14.1 1.6 7.4 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_15 PF13429.1 KKK14753.1 - 0.00093 18.3 2.9 0.00093 18.3 2.0 4.0 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK14753.1 - 0.0011 19.2 24.9 37 5.0 0.2 10.2 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK14753.1 - 0.0012 18.4 13.6 7 6.7 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 KKK14753.1 - 2 8.4 11.5 16 5.5 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 KKK14754.1 - 6.2e-71 238.2 0.0 7.3e-71 238.0 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Arylsulfotran_2 PF14269.1 KKK14755.1 - 3.2e-62 210.3 5.7 4.8e-62 209.8 4.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KKK14755.1 - 2.9e-17 62.3 5.2 5.8e-17 61.3 3.6 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) NMT1 PF09084.6 KKK14756.1 - 6.6e-78 261.2 0.0 8.3e-78 260.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KKK14756.1 - 7.7e-09 35.3 1.4 0.028 13.7 0.0 3.2 2 1 0 3 3 3 3 NMT1-like family Phosphonate-bd PF12974.2 KKK14756.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Fungal_trans PF04082.13 KKK14757.1 - 1.1e-36 126.0 2.0 1.6e-36 125.4 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14757.1 - 0.0015 18.4 18.5 0.003 17.4 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_C PF00137.16 KKK14758.1 - 0.036 13.9 6.1 0.041 13.7 4.2 1.1 1 0 0 1 1 1 0 ATP synthase subunit C MFS_1 PF07690.11 KKK14758.1 - 5.3 5.6 6.2 5.3 5.6 4.3 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily SKG6 PF08693.5 KKK14758.1 - 6.2 6.2 5.6 7 6.0 3.9 1.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Asp PF00026.18 KKK14764.1 - 2.6e-74 250.3 5.5 3.1e-74 250.0 3.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK14764.1 - 1.4e-12 47.8 1.5 9e-12 45.2 0.6 2.6 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KKK14764.1 - 3e-07 30.8 0.6 0.0045 17.4 0.1 3.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KKK14764.1 - 2.4e-05 23.9 0.0 5.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KKK14764.1 - 0.039 13.7 0.1 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease MFS_1_like PF12832.2 KKK14764.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 MFS_1 like family tRNA-synt_1b PF00579.20 KKK14765.1 - 2.2e-69 233.8 0.0 2.8e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ATP-synt_C PF00137.16 KKK14775.1 - 2.1e-26 91.5 23.8 5.6e-16 58.1 4.9 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Lysis_S PF04971.7 KKK14775.1 - 0.088 12.5 2.3 0.18 11.5 0.0 2.5 3 0 0 3 3 3 0 Lysis protein S Oxidored_q2 PF00420.19 KKK14775.1 - 1 8.9 8.1 0.83 9.2 2.7 2.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ras PF00071.17 KKK14776.1 - 2.7e-59 199.1 0.2 3.5e-59 198.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK14776.1 - 8e-21 74.7 0.0 1.2e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK14776.1 - 1.5e-17 63.3 0.1 1.8e-17 63.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK14776.1 - 2.5e-07 30.3 0.0 1.1e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KKK14776.1 - 2.6e-06 26.7 0.0 3.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KKK14776.1 - 4e-06 26.1 0.1 5e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK14776.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KKK14776.1 - 0.02 14.6 0.1 2.9 7.6 0.0 2.6 2 1 1 3 3 3 0 Dynamin family AAA_14 PF13173.1 KKK14776.1 - 0.043 13.7 0.2 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KKK14776.1 - 0.12 12.2 0.0 3.1 7.7 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KKK14776.1 - 0.13 12.4 0.0 1.1 9.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain NIR_SIR PF01077.17 KKK14778.1 - 2.8e-46 156.7 0.0 2.7e-42 143.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KKK14778.1 - 3.6e-30 103.4 0.0 2.9e-14 52.4 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KKK14778.1 - 1.4e-25 89.9 0.0 3.2e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KKK14778.1 - 1.6e-08 34.3 0.5 8.3e-08 32.0 0.1 2.1 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 KKK14779.1 - 1.9e-59 200.5 0.5 2.3e-59 200.2 0.3 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 RNA_pol PF00940.14 KKK14780.1 - 4.6e-151 502.8 0.0 2.5e-149 497.1 0.0 2.1 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KKK14780.1 - 2.1e-77 260.5 0.3 3.5e-77 259.7 0.2 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal TPR_16 PF13432.1 KKK14780.1 - 0.063 13.9 0.1 13 6.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Sin_N PF04801.8 KKK14781.1 - 7.6e-25 87.6 0.0 1.5e-24 86.6 0.0 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region Aldedh PF00171.17 KKK14784.1 - 1.1e-133 446.0 0.3 1.3e-133 445.7 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KKK14784.1 - 0.039 12.6 0.0 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Yos1 PF08571.5 KKK14786.1 - 4.4e-12 45.9 1.4 4.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Yos1-like UCH PF00443.24 KKK14787.1 - 4.9e-65 219.3 0.1 9.3e-65 218.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK14787.1 - 1.3e-30 106.8 1.0 1.2e-22 80.6 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KKK14787.1 - 0.007 15.6 3.6 0.041 13.1 1.2 2.5 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2252 PF10009.4 KKK14787.1 - 0.28 10.0 5.5 0.59 8.9 3.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Dynamitin PF04912.9 KKK14788.1 - 2.6e-18 66.0 2.6 2.6e-18 66.0 1.8 1.7 2 0 0 2 2 2 1 Dynamitin IncA PF04156.9 KKK14788.1 - 0.0097 15.5 10.8 0.0097 15.5 7.5 2.1 2 1 0 2 2 2 1 IncA protein CorA PF01544.13 KKK14788.1 - 0.048 12.6 3.3 0.092 11.7 2.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Vfa1 PF08432.5 KKK14788.1 - 0.051 13.6 5.6 0.17 11.9 2.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TBPIP PF07106.8 KKK14788.1 - 1 8.8 6.0 0.25 10.8 1.6 1.9 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GrpE PF01025.14 KKK14788.1 - 2 7.9 9.1 0.47 9.9 2.3 2.4 2 0 0 2 2 2 0 GrpE Prefoldin PF02996.12 KKK14788.1 - 2.4 7.8 9.5 5.2 6.7 0.0 3.4 3 1 0 4 4 4 0 Prefoldin subunit Spc24 PF08286.6 KKK14788.1 - 7.5 6.2 9.6 0.64 9.7 2.1 2.5 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 SPX PF03105.14 KKK14788.1 - 7.8 6.1 16.2 22 4.7 0.2 2.3 2 1 0 2 2 2 0 SPX domain Glyco_transf_22 PF03901.12 KKK14789.1 - 4.1e-37 128.1 14.3 5e-37 127.8 9.9 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3267 PF11667.3 KKK14789.1 - 0.0039 17.3 2.6 0.011 15.8 1.2 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3267) QRPTase_C PF01729.14 KKK14790.1 - 1.9e-47 160.9 0.6 3e-45 153.7 0.4 2.1 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KKK14790.1 - 6.9e-23 80.2 0.0 2.2e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Aldose_epim PF01263.15 KKK14791.1 - 1.3e-58 198.5 0.0 1.4e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Sec7 PF01369.15 KKK14792.1 - 3.7e-42 144.1 0.0 8.1e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KKK14792.1 - 1.3e-19 70.4 0.0 8.4e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Microtub_assoc PF07989.6 KKK14793.1 - 2.6e-24 84.8 10.3 2.6e-24 84.8 7.2 7.4 7 2 1 8 8 8 1 Microtubule associated Mto2_bdg PF12808.2 KKK14793.1 - 2.1e-22 78.9 29.2 3.8e-19 68.5 8.5 11.6 11 2 1 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 KKK14793.1 - 0.0005 19.3 1.5 0.0005 19.3 1.0 5.8 5 1 1 6 6 6 4 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 KKK14793.1 - 0.006 16.3 12.2 0.006 16.3 8.5 10.0 7 2 5 12 12 12 2 TATA element modulatory factor 1 TATA binding Zn_clus PF00172.13 KKK14794.1 - 1.2e-08 34.7 12.8 2.3e-08 33.7 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.17 KKK14795.1 - 2.6e-37 127.6 0.0 3.1e-36 124.1 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK14795.1 - 1.4e-10 41.7 0.0 3.1e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KKK14795.1 - 0.0052 16.7 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KKK14795.1 - 0.022 13.9 0.0 0.057 12.6 0.0 1.7 1 1 1 2 2 2 0 ADP-ribosylation factor family PRK PF00485.13 KKK14795.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family UNC-50 PF05216.8 KKK14796.1 - 4.7e-84 281.2 4.6 5.9e-84 280.8 3.2 1.1 1 0 0 1 1 1 1 UNC-50 family RibD_C PF01872.12 KKK14797.1 - 3e-34 118.3 0.0 3.6e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Reo_sigmaC PF04582.7 KKK14798.1 - 0.57 9.3 3.3 2.4 7.2 2.3 1.9 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF3431 PF11913.3 KKK14800.1 - 1.9e-82 276.0 0.1 2.6e-82 275.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Phage_holin_5 PF06946.6 KKK14801.1 - 1 9.5 10.1 0.13 12.4 0.3 2.8 3 0 0 3 3 3 0 Phage holin Bestrophin PF01062.16 KKK14802.1 - 5.3e-49 166.7 1.3 2.1e-47 161.4 0.9 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF167 PF02594.11 KKK14804.1 - 2.3e-12 46.6 0.1 3.5e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 UBA_4 PF14555.1 KKK14805.1 - 1.7e-11 43.4 0.1 3.3e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.15 KKK14805.1 - 1.1 9.0 6.3 0.13 11.8 1.1 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif FHA PF00498.21 KKK14806.1 - 4.4e-13 49.1 0.2 1.1e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 FHA domain Pkinase PF00069.20 KKK14807.1 - 1.4e-72 244.0 0.0 1.8e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14807.1 - 3.7e-36 124.5 0.0 5.1e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KKK14807.1 - 4.1e-08 33.2 0.0 8.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KKK14807.1 - 4.2e-06 25.9 0.0 6.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KKK14807.1 - 4.1e-05 23.0 0.1 8.7e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KKK14807.1 - 0.0068 15.0 0.1 0.01 14.4 0.1 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC GSK-3_bind PF05350.7 KKK14807.1 - 0.021 14.2 6.6 0.043 13.2 4.6 1.5 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Kdo PF06293.9 KKK14807.1 - 0.028 13.4 0.2 0.13 11.2 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phostensin_N PF13916.1 KKK14807.1 - 0.029 14.3 2.3 0.085 12.8 1.6 1.9 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal APH PF01636.18 KKK14807.1 - 0.083 12.6 0.1 0.083 12.6 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KKK14807.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DnaJ_CXXCXGXG PF00684.14 KKK14808.1 - 0.54 10.3 9.6 1.8 8.6 1.8 2.6 1 1 2 3 3 3 0 DnaJ central domain zf-Paramyx-P PF13008.2 KKK14808.1 - 1.3 8.3 5.6 2.8 7.2 0.1 2.5 2 1 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein TFIIB PF00382.14 KKK14809.1 - 8.4e-33 112.0 0.9 1.4e-17 63.2 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KKK14809.1 - 3.8e-27 94.3 0.5 1.2e-26 92.7 0.0 2.2 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KKK14809.1 - 7.8e-06 25.4 0.0 0.059 12.9 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 KKK14809.1 - 0.00045 19.4 2.3 0.001 18.3 1.6 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding RRN7 PF11781.3 KKK14809.1 - 0.022 14.2 0.2 0.052 13.0 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 KKK14809.1 - 0.042 13.7 1.2 0.082 12.7 0.8 1.4 1 0 0 1 1 1 0 IBR domain E1-E2_ATPase PF00122.15 KKK14810.1 - 4.9e-53 179.5 0.0 2.1e-52 177.4 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 KKK14810.1 - 3.3e-42 142.4 0.5 4.8e-10 39.4 0.1 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 KKK14810.1 - 3.7e-35 122.2 0.0 7.6e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK14810.1 - 6.6e-18 65.5 0.0 1.4e-17 64.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK14810.1 - 1.3e-05 24.9 0.0 0.0065 16.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Peptidase_M18 PF02127.10 KKK14823.1 - 6.8e-167 555.3 0.0 7.7e-167 555.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) WD40 PF00400.27 KKK14824.1 - 6.8e-36 120.8 7.0 1.6e-07 30.9 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KKK14824.1 - 5.4e-08 32.7 0.1 0.0087 15.7 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A ATPgrasp_ST PF14397.1 KKK14824.1 - 0.057 12.5 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Pyrophosphatase PF00719.14 KKK14825.1 - 3.7e-52 175.8 0.2 5.1e-52 175.4 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.4 KKK14826.1 - 1.6e-07 31.1 3.3 3.4e-07 30.1 2.3 1.6 1 1 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF1746 PF08508.5 KKK14827.1 - 1.1e-42 144.6 1.3 1.6e-42 144.1 0.9 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Dus PF01207.12 KKK14828.1 - 1.2e-43 149.0 0.1 3.2e-43 147.7 0.1 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) COX5A PF02284.11 KKK14828.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va PrmA PF06325.8 KKK14828.1 - 0.15 11.1 0.0 0.32 10.0 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) RPN7 PF10602.4 KKK14829.1 - 3.6e-52 176.3 0.6 5.3e-52 175.7 0.4 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Aminotran_1_2 PF00155.16 KKK14829.1 - 1.5e-40 139.3 0.0 2.9e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II PCI PF01399.22 KKK14829.1 - 3.2e-15 56.3 0.0 9.7e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 PCI domain CytochromB561_N PF09786.4 KKK14829.1 - 0.14 10.5 0.2 0.21 9.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal PEX11 PF05648.9 KKK14830.1 - 2.1e-74 249.5 0.6 2.4e-74 249.3 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Mito_carr PF00153.22 KKK14832.1 - 7.8e-56 185.7 3.1 2.2e-21 75.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-Nse PF11789.3 KKK14833.1 - 6.9e-23 79.9 0.1 1.2e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 KKK14833.1 - 0.00023 20.8 0.1 0.00039 20.1 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KKK14833.1 - 0.0051 16.4 0.2 0.042 13.5 0.0 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 KKK14833.1 - 0.041 13.4 2.1 0.2 11.1 0.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF1943 PF09172.6 KKK14833.1 - 0.16 10.7 2.3 0.34 9.7 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Na_H_Exchanger PF00999.16 KKK14834.1 - 7.8e-38 129.9 16.3 9.9e-38 129.6 11.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KKK14834.1 - 0.0066 16.3 1.2 0.67 9.9 0.0 3.4 3 0 0 3 3 3 1 YrhC-like protein Lipoprotein_18 PF06804.6 KKK14834.1 - 0.026 13.2 0.0 0.039 12.6 0.0 1.1 1 0 0 1 1 1 0 NlpB/DapX lipoprotein DUF3329 PF11808.3 KKK14834.1 - 3.8 7.6 5.1 2.2 8.4 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3329) PEPCK_ATP PF01293.15 KKK14835.1 - 8.6e-216 716.9 0.0 1e-215 716.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 KKK14835.1 - 0.031 14.5 0.0 7.5 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KKK14835.1 - 0.042 13.2 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KKK14835.1 - 0.086 12.7 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KKK14835.1 - 0.19 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.13 KKK14836.1 - 2.7e-76 255.5 0.2 6.5e-76 254.2 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Vps39_2 PF10367.4 KKK14836.1 - 1.2e-34 118.7 0.2 5.3e-34 116.6 0.0 2.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KKK14836.1 - 7.4e-34 116.0 0.0 6.6e-32 109.7 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 His_Phos_1 PF00300.17 KKK14836.1 - 1.9e-33 115.8 0.0 4.1e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CNH PF00780.17 KKK14836.1 - 1.5e-18 67.2 0.0 5.7e-18 65.2 0.0 1.8 1 1 0 1 1 1 1 CNH domain AAA_33 PF13671.1 KKK14836.1 - 9.1e-07 28.8 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KKK14836.1 - 0.0001 21.5 0.0 0.00026 20.2 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Clathrin PF00637.15 KKK14836.1 - 0.00038 20.0 0.6 0.00038 20.0 0.4 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.23 KKK14836.1 - 0.28 10.8 1.9 29 4.4 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Gon7 PF08738.5 KKK14837.1 - 1.1e-19 70.3 1.6 3.8e-18 65.3 1.1 2.0 1 1 0 1 1 1 1 Gon7 family HbrB PF08539.6 KKK14838.1 - 8.8e-60 201.1 0.0 1.3e-59 200.5 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Myb_DNA-bind_5 PF13873.1 KKK14839.1 - 0.00016 21.4 0.4 0.04 13.8 0.0 2.8 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain PTSIIB_sorb PF03830.10 KKK14839.1 - 0.053 13.3 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 PTS system sorbose subfamily IIB component Pol_alpha_B_N PF08418.5 KKK14839.1 - 0.092 12.2 9.6 0.15 11.5 6.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MAGUK_N_PEST PF10608.4 KKK14839.1 - 0.25 11.7 3.2 0.51 10.7 2.2 1.4 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK TACC PF05010.9 KKK14839.1 - 0.36 10.5 2.7 0.49 10.1 1.9 1.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) RRM_6 PF14259.1 KKK14840.1 - 7.4e-20 70.7 0.0 7.3e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK14840.1 - 1.2e-19 69.6 0.2 2.3e-13 49.5 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK14840.1 - 2.7e-10 39.9 0.0 0.00073 19.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KKK14840.1 - 0.0049 16.6 0.0 1.5 8.5 0.0 3.2 3 0 0 3 3 3 1 Limkain b1 Laminin_G_2 PF02210.19 KKK14840.1 - 0.12 12.3 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain TC1 PF15063.1 KKK14840.1 - 0.16 11.5 1.5 8.7 5.9 0.0 2.9 2 1 0 2 2 2 0 Thyroid cancer protein 1 AAA PF00004.24 KKK14841.1 - 1.9e-16 60.4 0.0 6.8e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KKK14841.1 - 2.4e-05 23.9 0.1 7.1e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KKK14841.1 - 0.00014 22.0 0.9 0.003 17.7 0.6 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK14841.1 - 0.00052 19.7 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK14841.1 - 0.0089 16.0 3.6 0.016 15.2 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KKK14841.1 - 0.032 14.1 1.3 0.067 13.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KKK14841.1 - 0.036 14.8 2.8 0.063 14.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KKK14841.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.1 3 1 1 4 4 4 0 AAA domain Ribosomal_S7 PF00177.16 KKK14850.1 - 1e-38 132.2 1.1 1.3e-38 131.8 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.7 KKK14851.1 - 6.2e-99 331.3 28.0 6.2e-99 331.3 19.4 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KKK14851.1 - 3e-09 37.0 2.3 7.5e-09 35.7 1.6 1.7 1 0 0 1 1 1 1 NUC130/3NT domain AMP-binding PF00501.23 KKK14852.1 - 4.2e-59 200.0 0.3 9.8e-33 113.1 0.0 4.4 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 KKK14852.1 - 5.3e-10 39.8 0.0 1.9e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.7 KKK14852.1 - 0.0021 17.8 0.3 0.0042 16.8 0.2 1.5 1 0 0 1 1 1 1 Gas vesicle protein G DUF4032 PF13224.1 KKK14852.1 - 0.21 11.2 0.1 18 4.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4032) ATG27 PF09451.5 KKK14853.1 - 2e-59 201.0 0.0 2.3e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 AAA_2 PF07724.9 KKK14855.1 - 7.8e-46 156.1 0.0 2.1e-44 151.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KKK14855.1 - 1.3e-27 96.5 0.0 1.8e-15 57.3 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KKK14855.1 - 1.5e-24 85.6 0.4 5.2e-24 83.9 0.3 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KKK14855.1 - 8.3e-16 58.5 14.5 6.6e-06 26.2 0.0 5.8 4 3 2 6 6 5 3 AAA ATPase domain AAA_5 PF07728.9 KKK14855.1 - 1.5e-15 57.1 0.0 1.1e-09 38.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KKK14855.1 - 2.7e-15 56.6 0.0 1.7e-05 24.9 0.0 4.1 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 KKK14855.1 - 9.3e-09 36.1 2.7 0.0082 16.9 0.0 3.9 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KKK14855.1 - 1.7e-08 34.1 0.0 2.6e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.15 KKK14855.1 - 7.9e-08 32.1 0.7 0.00034 20.4 0.0 4.3 3 0 0 3 3 3 1 Clp amino terminal domain IstB_IS21 PF01695.12 KKK14855.1 - 1.2e-07 31.2 0.0 0.021 14.2 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KKK14855.1 - 1.9e-07 31.0 0.0 0.019 14.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KKK14855.1 - 9.1e-07 29.2 2.9 0.026 14.8 0.0 4.0 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.1 KKK14855.1 - 1e-06 28.4 2.4 0.018 14.7 0.0 3.2 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 KKK14855.1 - 5.4e-06 25.7 0.5 0.15 11.1 0.0 4.2 3 1 0 4 4 4 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KKK14855.1 - 4.6e-05 23.5 0.0 0.42 10.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 KKK14855.1 - 6.2e-05 22.9 0.0 0.22 11.4 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 KKK14855.1 - 7.2e-05 22.8 2.7 0.31 10.9 0.0 3.7 3 1 1 4 4 3 2 AAA domain MobB PF03205.9 KKK14855.1 - 0.00013 21.6 0.0 0.77 9.4 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KKK14855.1 - 0.00014 20.8 0.0 0.0071 15.2 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 KKK14855.1 - 0.0002 21.1 14.8 0.013 15.1 0.3 5.3 5 2 0 6 6 4 2 Archaeal ATPase AAA_25 PF13481.1 KKK14855.1 - 0.00025 20.5 0.3 1.7 7.9 0.0 3.9 3 1 1 4 4 3 2 AAA domain AAA_3 PF07726.6 KKK14855.1 - 0.00039 20.0 0.0 1.3 8.5 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KKK14855.1 - 0.00041 20.6 3.8 0.55 10.5 0.0 3.8 4 0 0 4 4 3 1 ABC transporter AAA_29 PF13555.1 KKK14855.1 - 0.00063 19.2 0.0 0.48 9.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KKK14855.1 - 0.0009 18.4 0.0 0.42 9.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ResIII PF04851.10 KKK14855.1 - 0.0017 18.2 1.6 0.47 10.2 0.0 4.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_10 PF12846.2 KKK14855.1 - 0.0027 17.1 5.3 1.2 8.5 0.0 4.7 4 2 1 6 6 6 1 AAA-like domain AAA_24 PF13479.1 KKK14855.1 - 0.0028 17.2 0.0 1.7 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KKK14855.1 - 0.0032 17.1 0.0 0.23 11.1 0.0 3.2 3 0 0 3 3 3 1 NTPase NACHT PF05729.7 KKK14855.1 - 0.0053 16.4 0.0 0.43 10.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 KKK14855.1 - 0.0084 16.1 0.0 1.9 8.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Torsin PF06309.6 KKK14855.1 - 0.023 14.5 0.0 0.08 12.8 0.0 1.8 2 0 0 2 2 1 0 Torsin SRP54 PF00448.17 KKK14855.1 - 0.025 14.0 0.0 6.8 6.0 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 KKK14855.1 - 0.044 13.4 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 KKK14855.1 - 0.081 12.8 0.0 2.1 8.3 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KKK14855.1 - 0.1 12.1 0.0 21 4.5 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Caldesmon PF02029.10 KKK14855.1 - 0.17 10.2 16.7 0.14 10.5 9.4 2.0 2 0 0 2 2 2 0 Caldesmon Viral_P18 PF04521.8 KKK14855.1 - 1.3 8.4 6.4 3 7.3 0.3 2.6 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Occludin_ELL PF07303.8 KKK14855.1 - 1.5 9.5 12.0 0.5 11.1 5.3 2.4 2 0 0 2 2 1 0 Occludin homology domain V_ATPase_I PF01496.14 KKK14855.1 - 2.3 5.9 4.4 4.3 5.0 3.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KKK14855.1 - 2.9 7.4 9.5 9.7 5.7 6.6 1.9 1 0 0 1 1 1 0 IncA protein SNF2_N PF00176.18 KKK14856.1 - 2.6e-64 216.8 0.0 3.9e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK14856.1 - 8.5e-12 44.7 0.0 3.9e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK14856.1 - 0.00022 21.1 0.2 0.00084 19.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.14 KKK14856.1 - 0.35 11.3 4.6 1.1 9.6 3.2 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein AA_permease_2 PF13520.1 KKK14859.1 - 4.6e-45 153.9 51.1 5.5e-45 153.6 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK14859.1 - 5.4e-22 77.7 44.3 7.5e-22 77.3 30.7 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM173 PF15009.1 KKK14859.1 - 0.017 13.9 1.3 0.092 11.5 0.0 2.4 2 1 1 3 3 3 0 Transmembrane protein 173 Tubulin_3 PF14881.1 KKK14860.1 - 1.1e-83 279.2 0.0 2.8e-83 277.8 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain HSP70 PF00012.15 KKK14860.1 - 3.4e-60 203.5 3.2 2.4e-58 197.4 0.0 3.1 3 0 0 3 3 3 2 Hsp70 protein Misat_Tub_SegII PF10644.4 KKK14860.1 - 1.4e-23 83.1 2.2 1.1e-22 80.1 0.0 3.3 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain RNR_inhib PF08591.5 KKK14861.1 - 2.3e-17 63.7 0.3 5.1e-17 62.5 0.2 1.6 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor DUF2347 PF09804.4 KKK14862.1 - 1.3e-105 352.7 0.0 2.2e-105 351.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KKK14862.1 - 6.6e-64 215.2 1.3 7.3e-64 215.0 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 KKK14862.1 - 0.0084 14.6 0.0 2.8 6.3 0.0 2.4 2 1 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 KKK14862.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis DUF1523 PF07509.6 KKK14862.1 - 0.13 11.4 0.1 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Pkinase PF00069.20 KKK14886.1 - 1.1e-67 227.9 0.0 1.7e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14886.1 - 5.3e-35 120.7 0.0 8.1e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KKK14886.1 - 2.7e-17 61.9 0.3 4.7e-17 61.1 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KKK14886.1 - 5.2e-05 22.4 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KKK14886.1 - 5.6e-05 22.2 0.0 9.4e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KKK14886.1 - 0.0015 17.8 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KKK14886.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK14886.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fungal_trans PF04082.13 KKK14892.1 - 9.5e-44 149.2 0.1 1.6e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14892.1 - 4.5e-08 32.8 7.9 9e-08 31.9 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 KKK14892.1 - 0.0083 15.7 3.6 0.017 14.8 2.5 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KKK14892.1 - 2.3 8.0 8.4 4.1 7.1 5.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 RTA1 PF04479.8 KKK14893.1 - 1.8e-37 129.0 13.9 1.5e-36 126.0 9.6 1.9 1 1 0 1 1 1 1 RTA1 like protein Cyclin_N PF00134.18 KKK14893.1 - 0.0088 15.6 0.7 0.015 14.8 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L30_N PF08079.7 KKK14894.1 - 2.5e-26 91.4 16.2 4.8e-26 90.5 11.2 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KKK14894.1 - 6.2e-16 57.7 3.1 7.3e-16 57.5 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e EAP30 PF04157.11 KKK14895.1 - 2.2e-59 200.3 0.0 2.8e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 KKK14895.1 - 0.0079 15.8 0.4 0.03 13.9 0.0 2.2 3 0 0 3 3 3 1 MarR family PRK PF00485.13 KKK14896.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DUF500 PF04366.7 KKK14897.1 - 8.1e-45 151.3 0.0 1.6e-44 150.4 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) Peptidase_S10 PF00450.17 KKK14898.1 - 1.2e-86 291.4 0.1 2.1e-86 290.7 0.1 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase DnaJ PF00226.26 KKK14899.1 - 2.5e-27 94.4 5.5 3.7e-27 93.8 3.8 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KKK14899.1 - 1.8e-24 85.3 0.4 5e-22 77.6 0.0 2.7 2 1 0 2 2 2 2 DnaJ C terminal domain PIG-X PF08320.7 KKK14900.1 - 3.9e-77 258.2 0.0 5.3e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 APH PF01636.18 KKK14902.1 - 1.1e-11 44.9 0.0 1.2e-09 38.2 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KKK14902.1 - 0.0025 17.0 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF4034 PF13226.1 KKK14903.1 - 0.04 13.0 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) REF PF05755.7 KKK14903.1 - 0.12 12.1 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) CoA_trans PF01144.18 KKK14904.1 - 6.4e-95 316.4 4.5 1.1e-52 178.4 0.5 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF531 PF04407.7 KKK14904.1 - 0.071 12.9 0.0 0.39 10.5 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF531) Rrn6 PF10214.4 KKK14905.1 - 0.27 9.3 5.4 0.26 9.3 3.8 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF822 PF05687.8 KKK14905.1 - 1.7 9.0 6.3 2.2 8.6 4.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Tim17 PF02466.14 KKK14906.1 - 3.1e-15 56.3 8.7 4.5e-15 55.8 6.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UCH PF00443.24 KKK14907.1 - 2.9e-48 164.3 0.0 1.9e-47 161.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KKK14907.1 - 1e-46 156.1 1.7 1.1e-22 79.1 0.1 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 KKK14907.1 - 1e-11 44.8 0.5 1.3e-06 28.1 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase E7 PF00527.13 KKK14907.1 - 0.025 14.7 0.0 0.13 12.4 0.0 2.2 1 0 0 1 1 1 0 E7 protein, Early protein PUB PF09409.5 KKK14907.1 - 0.16 11.7 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 PUB domain Pkinase PF00069.20 KKK14908.1 - 6.1e-68 228.7 0.0 8e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14908.1 - 5.8e-29 100.9 0.0 9.7e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK14908.1 - 0.03 14.0 1.3 0.067 12.9 0.0 2.0 2 2 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KKK14908.1 - 0.048 12.7 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 KKK14909.1 - 2.7e-55 187.7 0.0 3.6e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EpuA PF11772.3 KKK14909.1 - 0.023 14.1 0.1 5.6 6.4 0.0 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta DUF2370 PF10176.4 KKK14911.1 - 8.1e-84 280.5 1.2 8.7e-84 280.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) Ebola_NP PF05505.7 KKK14911.1 - 1.9 6.4 7.9 2.9 5.8 5.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Abhydrolase_6 PF12697.2 KKK14912.1 - 1.7e-22 80.4 0.0 2.4e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK14912.1 - 2.6e-07 30.4 0.0 8.1e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK14912.1 - 4.5e-07 29.7 0.0 1.1e-06 28.4 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KKK14912.1 - 0.00082 19.6 0.0 0.00097 19.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_8 PF06259.7 KKK14912.1 - 0.082 12.3 0.1 0.76 9.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase tRNA-synt_2b PF00587.20 KKK14914.1 - 5.1e-44 149.8 0.0 9.3e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KKK14914.1 - 2.3e-17 62.6 0.2 4.8e-17 61.6 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KKK14914.1 - 1.2e-13 50.6 0.0 2.5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KKK14914.1 - 8.1e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain DUF604 PF04646.7 KKK14915.1 - 2.7e-12 46.4 0.2 6.1e-12 45.2 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF604 CDP-OH_P_transf PF01066.16 KKK14916.1 - 2.4e-12 47.0 2.1 2.4e-12 47.0 1.5 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PqiA PF04403.8 KKK14916.1 - 0.08 12.5 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 Paraquat-inducible protein A Gar1 PF04410.9 KKK14917.1 - 1.4e-43 147.9 0.2 2.4e-43 147.2 0.0 1.4 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF1752 PF08550.5 KKK14930.1 - 0.0093 15.5 0.1 0.023 14.2 0.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) adh_short_C2 PF13561.1 KKK14931.1 - 1.3e-26 93.8 0.0 1.7e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK14931.1 - 4.3e-23 82.0 0.3 7.1e-23 81.3 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK14931.1 - 9.8e-13 48.1 0.1 1.6e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK14931.1 - 0.0023 17.4 0.2 0.0056 16.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2841 PF11001.3 KKK14932.1 - 5.2e-46 155.6 0.8 7.6e-46 155.0 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Fungal_trans PF04082.13 KKK14933.1 - 3.9e-14 52.1 0.0 6.1e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.26 KKK14967.1 - 1.2e-19 69.7 0.6 3.7e-19 68.2 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 KKK14967.1 - 0.037 13.6 0.1 0.14 11.8 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK14967.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 KKK14969.1 - 8.4e-05 22.5 0.2 8.4e-05 22.5 0.1 1.8 2 1 0 2 2 2 1 short chain dehydrogenase Rhomboid PF01694.17 KKK14969.1 - 0.071 13.1 0.2 0.09 12.8 0.1 1.2 1 0 0 1 1 1 0 Rhomboid family DIOX_N PF14226.1 KKK14970.1 - 8.8e-26 90.7 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK14970.1 - 7.3e-17 61.4 0.0 3.4e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.9 KKK14971.1 - 1.2e-35 123.3 3.2 3e-35 122.1 2.2 1.6 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KKK14971.1 - 0.0083 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase Homez PF11569.3 KKK14972.1 - 0.0074 15.3 0.2 0.017 14.1 0.1 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Mei4 PF13971.1 KKK14972.1 - 0.042 12.8 6.5 0.76 8.6 4.5 2.5 1 1 0 1 1 1 0 Meiosis-specific protein Mei4 R3H-assoc PF13902.1 KKK14972.1 - 0.063 13.2 1.3 1.3 8.9 0.3 2.4 2 0 0 2 2 2 0 R3H-associated N-terminal domain Striatin PF08232.7 KKK14972.1 - 0.42 10.9 6.4 0.68 10.2 1.5 2.8 3 0 0 3 3 3 0 Striatin family MeMO_Hyd_G PF02964.11 KKK14973.1 - 0.0034 17.3 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 Methane monooxygenase, hydrolase gamma chain AMP-binding PF00501.23 KKK14974.1 - 1.3e-69 234.5 0.0 1.9e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK14974.1 - 1.3e-14 54.8 0.2 7.7e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Response_reg PF00072.19 KKK14975.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Response regulator receiver domain GpcrRhopsn4 PF10192.4 KKK14975.1 - 0.049 12.8 5.1 0.099 11.8 3.5 1.4 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain LDB19 PF13002.2 KKK14976.1 - 2.9e-59 199.7 0.0 4.5e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 KKK14976.1 - 2.2e-08 34.0 0.0 7.3e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF4606 PF15379.1 KKK14976.1 - 0.095 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) SASRP1 PF15160.1 KKK14976.1 - 0.93 8.6 7.6 0.2 10.8 2.6 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 MRC1 PF09444.5 KKK14981.1 - 2.3e-25 89.6 18.9 2.3e-25 89.6 13.1 7.6 5 4 1 6 6 6 1 MRC1-like domain KR PF08659.5 KKK14981.1 - 2 8.0 5.7 0.82 9.3 1.0 2.3 2 0 0 2 2 2 0 KR domain COQ7 PF03232.8 KKK14982.1 - 3.7e-63 212.0 0.2 4.5e-63 211.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KKK14982.1 - 8.9e-06 26.0 0.2 2.9e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Rubrerythrin DUF1817 PF08847.6 KKK14982.1 - 0.03 13.8 0.0 1.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1817) SPT2 PF08243.6 KKK14982.1 - 0.95 9.7 4.5 1.6 9.0 3.1 1.3 1 0 0 1 1 1 0 SPT2 chromatin protein Plus-3 PF03126.13 KKK14983.1 - 2.9e-32 110.9 0.0 1.7e-31 108.4 0.0 2.2 2 0 0 2 2 2 1 Plus-3 domain Pkinase PF00069.20 KKK14984.1 - 1.8e-31 109.2 0.0 2.9e-29 102.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14984.1 - 5.5e-07 28.9 0.0 0.006 15.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KKK14984.1 - 0.029 14.0 0.2 0.61 9.7 0.1 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family LMWPc PF01451.16 KKK14985.1 - 1e-30 106.8 0.0 1.3e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase UPF0546 PF10639.4 KKK14986.1 - 1.4e-29 102.2 1.1 2e-29 101.6 0.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 Mito_fiss_reg PF05308.6 KKK14986.1 - 0.21 10.8 9.7 0.29 10.4 6.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator EamA PF00892.15 KKK14986.1 - 0.26 11.3 5.0 0.35 10.9 3.5 1.2 1 0 0 1 1 1 0 EamA-like transporter family CAP_N PF01213.14 KKK14986.1 - 7.1 5.8 7.6 9.2 5.4 5.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Chitin_synth_1 PF01644.12 KKK14987.1 - 8.7e-82 272.7 0.1 1.8e-81 271.7 0.0 1.6 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 KKK14987.1 - 7.1e-31 105.7 0.0 1.4e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KKK14987.1 - 2.2e-21 75.8 2.4 2.1e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KKK14987.1 - 7.7e-08 32.4 0.0 4.6e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KKK14987.1 - 1.4e-07 31.3 7.8 1.4e-07 31.3 5.4 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Ank_2 PF12796.2 KKK14988.1 - 5.7e-49 164.4 4.6 1.6e-19 70.0 0.0 4.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK14988.1 - 4e-28 97.2 2.8 2.9e-11 43.5 0.1 6.4 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 KKK14988.1 - 7e-25 85.5 5.1 1.4e-08 34.0 0.1 7.0 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 KKK14988.1 - 3.1e-23 79.5 2.5 3.5e-06 26.7 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KKK14988.1 - 5.8e-20 70.8 4.2 3e-10 39.9 0.2 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) AAA_31 PF13614.1 KKK14988.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sulfate_transp PF00916.15 KKK14989.1 - 0.0064 15.5 21.4 0.033 13.2 9.2 3.5 1 1 1 2 2 2 1 Sulfate transporter family DUF2809 PF10990.3 KKK14989.1 - 2.8 8.4 8.2 0.69 10.3 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2809) PhyH PF05721.8 KKK14991.1 - 4.2e-44 151.1 0.0 1.6e-43 149.1 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UTP15_C PF09384.5 KKK14992.1 - 8.8e-52 174.7 0.5 1.6e-51 173.8 0.4 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KKK14992.1 - 1.4e-28 97.6 5.3 1.2e-07 31.3 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KKK14992.1 - 0.0011 18.4 0.2 0.01 15.3 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain Cupin_8 PF13621.1 KKK14993.1 - 3.6e-26 92.1 0.0 6.1e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KKK14993.1 - 0.0042 16.3 0.1 0.0081 15.4 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 KKK14993.1 - 0.0091 15.4 0.0 0.034 13.6 0.0 1.9 2 0 0 2 2 2 1 Cupin domain CK_II_beta PF01214.13 KKK14994.1 - 2.2e-78 261.9 0.0 4.9e-78 260.8 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KKK14994.1 - 0.0017 18.9 7.3 0.0017 18.9 5.0 2.0 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 KKK14994.1 - 0.16 11.5 7.2 0.26 10.8 5.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin Rubella_E2 PF05749.6 KKK14994.1 - 0.17 11.1 1.9 0.28 10.4 1.3 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 DUF3439 PF11921.3 KKK14994.1 - 1.1 8.9 6.1 1.9 8.2 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CENP-B_dimeris PF09026.5 KKK14994.1 - 6.6 7.0 11.7 17 5.7 7.8 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Rad10 PF03834.9 KKK14995.1 - 7.4e-30 102.4 0.0 1.3e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KKK14995.1 - 0.00041 20.4 0.0 0.00086 19.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 KKK14995.1 - 0.00043 19.8 0.0 0.00092 18.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 KKK14995.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Fungal_trans_2 PF11951.3 KKK14996.1 - 1.7e-13 49.9 0.8 2.4e-13 49.4 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Apc15p PF05841.6 KKK14996.1 - 5.2 7.8 6.9 1.3 9.7 1.8 2.1 2 0 0 2 2 2 0 Apc15p protein Cyt-b5 PF00173.23 KKK14997.1 - 4.2e-10 39.2 0.0 5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain bZIP_1 PF00170.16 KKK14998.1 - 2.8e-05 23.9 6.9 4.5e-05 23.3 4.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK14998.1 - 0.0015 18.3 8.5 0.0024 17.6 5.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK14998.1 - 0.032 14.5 4.9 0.053 13.8 3.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor RRM_1 PF00076.17 KKK14999.1 - 2.3e-51 171.3 0.0 9.3e-17 60.4 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK14999.1 - 3.2e-36 123.1 0.0 7.5e-14 51.4 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK14999.1 - 2.6e-15 55.9 0.0 2.3e-08 33.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2857 PF11198.3 KKK14999.1 - 0.021 14.3 1.2 0.045 13.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Nup35_RRM_2 PF14605.1 KKK14999.1 - 0.11 12.2 0.0 6 6.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CDC45 PF02724.9 KKK14999.1 - 2.9 5.8 30.0 0.077 11.0 9.4 2.4 2 0 0 2 2 2 0 CDC45-like protein AA_permease PF00324.16 KKK15000.1 - 8.9e-103 344.1 37.7 1.1e-96 324.0 17.5 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KKK15000.1 - 3.7e-19 68.5 25.7 3.7e-19 68.5 17.8 1.6 2 0 0 2 2 2 1 Amino acid permease DUF1772 PF08592.6 KKK15000.1 - 0.0061 16.3 0.3 0.0061 16.3 0.2 3.7 4 1 1 5 5 5 1 Domain of unknown function (DUF1772) Fungal_trans PF04082.13 KKK15001.1 - 9.2e-21 73.8 0.1 1.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15001.1 - 1.5e-06 27.9 14.2 2.6e-06 27.2 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.5 KKK15001.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 HalX domain Amidohydro_1 PF01979.15 KKK15002.1 - 2.8e-62 211.2 4.3 4.9e-62 210.5 3.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KKK15002.1 - 1.6e-56 189.6 0.7 3.1e-56 188.7 0.5 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KKK15002.1 - 2e-41 139.8 0.2 5.5e-41 138.4 0.0 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 KKK15002.1 - 8.5e-38 128.3 0.2 2.5e-37 126.8 0.1 1.9 2 0 0 2 2 2 1 Urease, gamma subunit HMG_box PF00505.14 KKK15002.1 - 4.9e-10 39.5 1.7 4.9e-10 39.5 1.2 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box Amidohydro_5 PF13594.1 KKK15002.1 - 7.2e-07 28.9 3.1 2.3e-06 27.3 2.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KKK15002.1 - 4.2e-05 22.9 2.3 8e-05 22.0 0.1 2.3 1 1 1 2 2 2 1 Amidohydrolase family HMG_box_2 PF09011.5 KKK15002.1 - 0.00011 22.4 0.7 0.00031 21.0 0.5 1.8 1 0 0 1 1 1 1 HMG-box domain POTRA_2 PF08479.6 KKK15002.1 - 0.053 13.1 0.1 0.34 10.6 0.0 2.2 1 1 1 2 2 2 0 POTRA domain, ShlB-type Daxx PF03344.10 KKK15002.1 - 0.46 8.9 14.3 0.67 8.3 9.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 KKK15002.1 - 6.5 6.7 20.0 14 5.6 13.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF4551 PF15087.1 KKK15002.1 - 10 4.3 7.9 14 3.8 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Lactamase_B_2 PF12706.2 KKK15003.1 - 7.7e-12 45.1 0.0 1.7e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KKK15003.1 - 2.1e-05 24.2 0.0 5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.9 KKK15003.1 - 0.00036 20.5 0.0 0.0014 18.5 0.0 2.0 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase NPR2 PF06218.6 KKK15004.1 - 2.6e-135 451.4 0.0 5.5e-135 450.3 0.0 1.5 2 0 0 2 2 2 1 Nitrogen permease regulator 2 LRR19-TM PF15176.1 KKK15004.1 - 0.015 14.9 3.8 0.04 13.5 2.6 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Afi1 PF07792.7 KKK15004.1 - 0.17 11.8 2.2 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.17 KKK15004.1 - 1.3 7.9 4.1 2 7.3 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 KKK15004.1 - 1.4 7.6 9.4 2 7.1 6.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-RING_2 PF13639.1 KKK15006.1 - 2.9e-13 49.4 5.2 4.7e-13 48.7 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KKK15006.1 - 8e-07 28.9 4.7 1.3e-06 28.3 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK15006.1 - 8.7e-06 25.3 3.6 1.4e-05 24.5 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK15006.1 - 1.3e-05 24.8 3.0 2.1e-05 24.1 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KKK15006.1 - 1.4e-05 25.1 0.3 2.8e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KKK15006.1 - 1.6e-05 24.4 2.8 2.6e-05 23.7 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TMEM154 PF15102.1 KKK15006.1 - 0.0017 18.0 1.5 0.0082 15.8 0.0 2.2 2 0 0 2 2 2 1 TMEM154 protein family zf-RING_UBOX PF13445.1 KKK15006.1 - 0.029 14.1 0.7 0.083 12.6 0.2 2.1 1 1 0 1 1 1 0 RING-type zinc-finger DUF4389 PF14333.1 KKK15006.1 - 0.036 13.7 0.2 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) BPD_transp_1 PF00528.17 KKK15006.1 - 0.038 13.5 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component zf-Apc11 PF12861.2 KKK15006.1 - 0.064 13.0 1.1 0.15 11.9 0.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 KKK15006.1 - 0.084 12.5 2.9 0.15 11.7 2.0 1.5 1 0 0 1 1 1 0 PHD-finger PgaD PF13994.1 KKK15006.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein DUF3377 PF11857.3 KKK15006.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Prok-RING_1 PF14446.1 KKK15006.1 - 0.22 11.2 3.9 0.23 11.2 0.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF912 PF06024.7 KKK15006.1 - 0.23 11.5 0.8 0.65 10.0 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-C3HC4_4 PF15227.1 KKK15006.1 - 0.23 11.3 4.2 0.6 10.0 2.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 KKK15006.1 - 0.75 9.8 2.7 1.4 9.0 1.9 1.5 1 0 0 1 1 1 0 RING-like domain Ada3 PF10198.4 KKK15007.1 - 2e-45 153.7 0.1 4.7e-45 152.5 0.1 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 HA2 PF04408.18 KKK15008.1 - 5.1e-29 100.2 0.2 2.2e-28 98.2 0.1 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KKK15008.1 - 3.6e-26 91.2 0.0 1.4e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KKK15008.1 - 3.7e-12 45.9 0.0 8.1e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KKK15008.1 - 3.6e-10 39.7 1.0 7.2e-10 38.8 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KKK15008.1 - 2.1e-05 24.1 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK15008.1 - 0.00011 22.3 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KKK15008.1 - 0.00023 20.1 0.0 0.00065 18.6 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KKK15008.1 - 0.015 15.0 0.2 0.042 13.6 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KKK15008.1 - 0.11 12.4 0.1 1.3 8.9 0.1 2.6 1 1 0 1 1 1 0 AAA domain RGS PF00615.14 KKK15011.1 - 1.7e-12 47.5 0.0 2.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF647 PF04884.9 KKK15012.1 - 1.6e-104 348.5 4.1 2.2e-104 348.0 2.8 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis PNK3P PF08645.6 KKK15013.1 - 2.6e-57 192.6 0.1 4e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KKK15013.1 - 4.8e-09 36.2 0.0 1.4e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain HAD_2 PF13419.1 KKK15013.1 - 0.0016 18.7 1.1 5 7.3 0.0 3.2 1 1 2 3 3 3 2 Haloacid dehalogenase-like hydrolase KTI12 PF08433.5 KKK15013.1 - 0.051 12.7 0.0 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Med18 PF09637.5 KKK15014.1 - 1.4e-67 227.8 0.0 1.6e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 KKK15015.1 - 1.7e-39 135.2 0.2 2e-39 135.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) CoA_trans PF01144.18 KKK15016.1 - 5.9e-94 313.2 3.1 8.3e-59 198.3 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KKK15016.1 - 0.02 14.5 1.2 0.025 14.2 0.0 1.7 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Fungal_trans PF04082.13 KKK15017.1 - 0.00075 18.4 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TIP120 PF08623.5 KKK15018.1 - 5.7e-62 208.2 0.2 2.9e-61 205.9 0.0 2.4 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 KKK15018.1 - 2.5e-09 36.4 14.2 0.024 14.7 0.0 8.6 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 KKK15018.1 - 6.1e-09 36.0 13.0 0.26 11.5 0.0 7.2 5 2 3 8 8 8 5 HEAT repeats Arm PF00514.18 KKK15018.1 - 0.00012 21.7 1.6 2.8 7.8 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KKK15018.1 - 0.00044 18.7 2.6 5.9 5.0 1.4 5.5 3 1 0 3 3 3 2 Adaptin N terminal region ParcG PF10274.4 KKK15018.1 - 0.044 13.6 0.8 32 4.3 0.0 3.6 2 1 1 3 3 3 0 Parkin co-regulated protein LRR_4 PF12799.2 KKK15019.1 - 8.8e-27 92.2 46.3 1e-06 28.2 1.3 8.9 6 2 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK15019.1 - 2.9e-24 84.5 34.1 7e-08 32.1 0.8 6.8 5 1 2 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 KKK15019.1 - 2.5e-07 29.7 41.0 0.5 10.5 0.1 12.5 11 3 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 KKK15019.1 - 9.4e-05 22.1 38.6 0.24 11.5 0.0 10.8 9 3 2 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 KKK15019.1 - 0.11 12.0 12.7 0.48 9.9 0.1 3.9 1 1 3 4 4 4 0 Leucine-rich repeat LRR_7 PF13504.1 KKK15019.1 - 0.19 12.0 49.0 4.5 7.9 0.1 12.0 12 1 1 13 13 13 0 Leucine rich repeat zf-ZPR1 PF03367.8 KKK15020.1 - 2.9e-96 319.1 0.1 2.4e-48 163.3 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-ribbon_3 PF13248.1 KKK15020.1 - 2.4 7.4 7.4 0.42 9.8 1.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Cytochrome_C7 PF14522.1 KKK15020.1 - 5.6 6.6 7.4 3 7.5 1.1 2.6 2 1 1 3 3 3 0 Cytochrome c7 DUF2435 PF10363.4 KKK15021.1 - 1.5e-26 92.0 0.1 2.1e-25 88.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KKK15021.1 - 2.7e-11 42.6 0.0 7.3e-11 41.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DBR1 PF05011.8 KKK15022.1 - 2.3e-50 170.2 1.0 4.3e-50 169.3 0.0 1.9 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KKK15022.1 - 8.3e-12 44.9 0.3 1.8e-11 43.8 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Rpr2 PF04032.11 KKK15023.1 - 2.9e-06 27.0 0.3 2.9e-06 27.0 0.2 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain CDC27 PF09507.5 KKK15023.1 - 0.34 10.0 5.3 0.48 9.6 3.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ORC6 PF05460.8 KKK15024.1 - 5.2e-99 331.6 0.1 6e-99 331.4 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Pro_isomerase PF00160.16 KKK15025.1 - 6.6e-31 107.6 0.0 3.1e-27 95.6 0.0 2.1 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAD_binding_8 PF08022.7 KKK15040.1 - 7.5e-20 70.7 0.0 1.5e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KKK15040.1 - 3.9e-19 69.0 0.0 8.1e-19 68.0 0.0 1.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KKK15040.1 - 2.7e-17 63.0 12.3 7e-17 61.6 8.5 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KKK15040.1 - 0.001 19.1 0.0 0.0036 17.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain AATase PF07247.7 KKK15041.1 - 6.7e-28 97.4 0.0 8.7e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KKK15041.1 - 7.6e-07 28.2 0.5 7.7e-06 24.9 0.0 2.1 2 0 0 2 2 2 1 Condensation domain NAC PF01849.13 KKK15042.1 - 4.8e-22 77.2 0.3 9.4e-22 76.3 0.2 1.5 1 0 0 1 1 1 1 NAC domain DUF3707 PF12499.3 KKK15043.1 - 0.018 15.3 1.1 0.03 14.6 0.7 1.3 1 0 0 1 1 1 0 Pherophorin DUF515 PF04415.7 KKK15043.1 - 0.59 8.3 2.3 0.72 8.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Med3 PF11593.3 KKK15043.1 - 3.2 6.9 13.0 3.8 6.6 9.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.11 KKK15045.1 - 2.5e-34 118.5 28.5 2.7e-33 115.1 20.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily NADH-u_ox-rdase PF10785.4 KKK15045.1 - 2.1 8.6 6.1 1.7 8.9 0.1 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Lipase_3 PF01764.20 KKK15046.1 - 1.6e-15 56.9 0.0 2.4e-14 53.1 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KKK15046.1 - 0.0042 16.9 0.1 0.0094 15.8 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK15046.1 - 0.0098 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family SMC_N PF02463.14 KKK15047.1 - 2.4e-23 82.5 0.0 5.6e-23 81.3 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KKK15047.1 - 6.3e-11 42.9 71.3 4.9e-09 36.8 18.9 5.0 2 2 1 3 3 2 1 AAA domain AAA_21 PF13304.1 KKK15047.1 - 1.2e-05 25.4 3.5 0.0012 18.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KKK15047.1 - 0.0022 17.4 0.0 0.0046 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KKK15047.1 - 0.018 14.4 0.6 0.086 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KKK15047.1 - 0.065 13.5 0.0 0.065 13.5 0.0 4.3 3 1 0 3 3 2 0 ABC transporter AAA_19 PF13245.1 KKK15047.1 - 0.17 11.6 0.0 0.53 10.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_13 PF13166.1 KKK15047.1 - 0.2 10.0 72.7 0.56 8.5 0.0 4.9 3 2 0 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 KKK15047.1 - 0.3 10.2 12.4 4.3 6.4 0.2 4.2 4 1 0 4 4 4 0 Reovirus sigma C capsid protein AAA PF00004.24 KKK15047.1 - 0.83 9.8 6.6 0.91 9.7 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KKK15047.1 - 2.1 9.2 5.9 1.6 9.6 0.0 3.5 2 1 0 2 2 2 0 AAA domain FMN_dh PF01070.13 KKK15048.1 - 2.1e-108 362.3 0.0 2.4e-108 362.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KKK15048.1 - 3.8e-05 22.9 0.4 6.5e-05 22.2 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 KKK15048.1 - 0.0017 17.4 0.1 0.23 10.4 0.1 2.4 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KKK15048.1 - 0.024 13.5 0.1 0.024 13.5 0.1 1.5 2 0 0 2 2 2 0 Conserved region in glutamate synthase IMPDH PF00478.20 KKK15048.1 - 0.094 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain HTH_AraC PF00165.18 KKK15048.1 - 0.15 11.8 0.1 1.5 8.7 0.0 2.6 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family Rab_eff_C PF04698.7 KKK15049.1 - 0.016 13.3 0.2 0.018 13.2 0.1 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Osmo_CC PF08946.5 KKK15049.1 - 0.031 14.3 5.0 3.1 7.9 0.1 2.5 1 1 1 2 2 2 0 Osmosensory transporter coiled coil Cortex-I_coil PF09304.5 KKK15049.1 - 0.039 13.9 2.3 0.049 13.6 1.6 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil Ctr PF04145.10 KKK15050.1 - 1.8e-35 122.0 0.4 2.2e-35 121.8 0.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Abhydrolase_2 PF02230.11 KKK15051.1 - 4.9e-61 205.9 0.0 5.6e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KKK15051.1 - 4.5e-12 45.9 0.0 6.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK15051.1 - 1.1e-08 35.3 0.0 0.0034 17.3 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 KKK15051.1 - 6.5e-07 29.0 0.0 2.1e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.9 KKK15051.1 - 0.00019 20.7 0.1 0.0027 16.9 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_3 PF07859.8 KKK15051.1 - 0.00023 20.8 0.0 0.00038 20.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK15051.1 - 0.00027 20.2 0.0 0.02 14.1 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KKK15051.1 - 0.00045 19.5 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.20 KKK15051.1 - 0.03 13.9 0.0 0.042 13.4 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.11 KKK15051.1 - 0.088 12.1 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.8 KKK15052.1 - 2e-36 125.4 0.0 2.4e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KKK15052.1 - 0.018 14.4 0.3 0.042 13.2 0.2 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KKK15052.1 - 0.029 14.1 0.2 0.043 13.5 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family FPN1 PF06963.7 KKK15059.1 - 4.1e-151 503.2 18.3 4.7e-151 503.0 12.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) HAD_2 PF13419.1 KKK15060.1 - 4.6e-16 59.5 0.0 6.8e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK15060.1 - 3.5e-07 29.8 0.0 6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KKK15060.1 - 0.00022 21.6 0.1 0.0017 18.7 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KKK15060.1 - 0.023 14.3 0.0 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Init_tRNA_PT PF04179.7 KKK15061.1 - 6e-173 575.8 0.0 6.8e-173 575.6 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Ribosomal_S16 PF00886.14 KKK15062.1 - 6.2e-25 86.6 0.1 8e-25 86.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 KKK15063.1 - 8.5e-25 87.2 0.0 2.2e-24 85.9 0.0 1.6 1 1 1 2 2 2 1 YjeF-related protein N-terminus RRM_1 PF00076.17 KKK15064.1 - 3.3e-16 58.6 0.0 6.2e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK15064.1 - 2e-10 40.5 0.0 1.6e-05 24.7 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CH PF00307.26 KKK15065.1 - 6.9e-34 116.1 0.1 5.3e-19 68.2 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KKK15065.1 - 8.2e-29 99.3 0.1 2.6e-28 97.7 0.1 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand RRM_1 PF00076.17 KKK15065.1 - 2e-17 62.5 0.0 4.4e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK15065.1 - 6.8e-11 41.9 0.0 1.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAMSAP_CH PF11971.3 KKK15065.1 - 1.3e-08 34.3 0.2 2.3e-07 30.3 0.0 2.8 2 0 0 2 2 2 1 CAMSAP CH domain FoP_duplication PF13865.1 KKK15065.1 - 6.7e-07 29.6 5.5 6.7e-07 29.6 3.8 3.3 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KKK15065.1 - 0.00026 20.7 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_6 PF13405.1 KKK15065.1 - 0.00086 18.9 0.0 0.0049 16.6 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 KKK15065.1 - 0.0044 16.2 0.1 0.035 13.3 0.0 2.5 2 0 0 2 2 2 1 EF hand DUF761 PF05553.6 KKK15065.1 - 0.0058 15.9 0.7 0.018 14.3 0.5 1.9 1 0 0 1 1 1 1 Cotton fibre expressed protein EF-hand_8 PF13833.1 KKK15065.1 - 0.01 15.4 0.1 0.043 13.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair Aldo_ket_red PF00248.16 KKK15066.1 - 2.4e-42 144.7 0.0 2.9e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ALMT PF11744.3 KKK15066.1 - 0.18 10.4 0.1 0.25 9.9 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PUL PF08324.6 KKK15067.1 - 1.9e-56 190.8 0.0 2.5e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 KKK15067.1 - 1.2e-43 147.7 0.1 2.1e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KKK15067.1 - 3.8e-38 127.9 15.1 4e-08 32.8 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KKK15067.1 - 0.0077 15.9 0.0 0.77 9.5 0.0 3.1 2 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 KKK15068.1 - 3.8e-34 115.3 10.8 1.2e-10 40.8 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Me-amine-dh_H PF06433.6 KKK15068.1 - 0.029 13.0 0.0 0.69 8.4 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) MutS_V PF00488.16 KKK15074.1 - 1.4e-88 296.2 0.0 2.8e-88 295.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KKK15074.1 - 4.4e-35 121.3 0.6 9.9e-35 120.1 0.4 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KKK15074.1 - 7.8e-13 48.4 0.0 2.7e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KKK15074.1 - 1.9e-10 40.9 0.0 7.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KKK15074.1 - 5.1e-07 29.7 0.1 1.4e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV p450 PF00067.17 KKK15075.1 - 1.3e-68 231.6 0.0 1.5e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 L31 PF09784.4 KKK15076.1 - 3.2e-47 158.8 1.9 3.6e-47 158.6 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Acyltransferase PF01553.16 KKK15077.1 - 7.9e-13 47.9 0.0 1.4e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase DEAD PF00270.24 KKK15080.1 - 1.6e-40 138.3 0.1 3.1e-40 137.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK15080.1 - 4.6e-22 77.6 0.0 2.8e-11 43.1 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Kelch_4 PF13418.1 KKK15083.1 - 2e-07 30.6 2.5 0.015 15.0 0.1 4.3 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK15083.1 - 0.046 13.6 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Kelch motif DUF706 PF05153.10 KKK15084.1 - 1.3e-118 394.8 0.7 1.6e-118 394.5 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 KKK15084.1 - 0.031 14.2 0.1 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 HD domain DUF19 PF01579.13 KKK15084.1 - 0.035 14.0 0.7 0.053 13.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF19) Glyco_hydro_76 PF03663.9 KKK15092.1 - 1.5e-134 449.0 21.5 1.9e-134 448.7 14.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Tub_2 PF04525.7 KKK15093.1 - 1.6e-07 30.9 0.0 7.2e-07 28.7 0.0 2.0 1 1 0 1 1 1 1 Tubby C 2 APH PF01636.18 KKK15094.1 - 0.0015 18.3 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family ADH_N PF08240.7 KKK15095.1 - 5e-22 77.7 0.1 8.4e-22 77.0 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK15095.1 - 1.9e-20 72.7 0.0 3.1e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-PARP PF00645.13 KKK15096.1 - 0.0051 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AAA_2 PF07724.9 KKK15097.1 - 3e-46 157.4 0.0 4.3e-44 150.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KKK15097.1 - 1.5e-26 92.0 0.2 5.1e-26 90.3 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KKK15097.1 - 1.6e-19 70.3 0.0 1.7e-10 41.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK15097.1 - 2.3e-13 50.0 1.3 1.6e-08 34.3 0.0 3.4 4 1 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK15097.1 - 4.1e-11 43.1 10.7 0.0001 22.3 0.0 5.5 4 2 1 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 KKK15097.1 - 5.9e-10 39.4 0.7 0.0033 17.5 0.0 3.4 2 1 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 KKK15097.1 - 2.1e-08 33.8 0.3 7.9e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 KKK15097.1 - 2e-06 27.7 0.0 0.065 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KKK15097.1 - 2.4e-06 27.4 5.0 0.049 13.3 0.0 4.6 3 2 0 3 3 3 1 Archaeal ATPase NACHT PF05729.7 KKK15097.1 - 8.7e-06 25.4 0.1 0.077 12.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KKK15097.1 - 1.8e-05 25.0 3.1 0.089 13.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 KKK15097.1 - 4.5e-05 23.1 0.0 0.022 14.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KKK15097.1 - 8e-05 23.4 7.7 0.039 14.7 0.1 4.0 3 2 0 3 3 3 2 AAA domain TrwB_AAD_bind PF10412.4 KKK15097.1 - 0.00015 20.5 0.1 0.063 11.8 0.0 2.6 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 KKK15097.1 - 0.00019 21.1 0.0 0.011 15.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KKK15097.1 - 0.00027 20.4 0.0 0.78 9.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein SRP54 PF00448.17 KKK15097.1 - 0.00027 20.4 0.0 0.044 13.2 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KKK15097.1 - 0.00037 20.5 5.0 0.056 13.3 0.0 3.9 4 1 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 KKK15097.1 - 0.00079 19.5 0.0 0.61 10.2 0.0 2.8 2 1 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 KKK15097.1 - 0.0026 18.0 1.1 1.7 8.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 KKK15097.1 - 0.0027 16.9 0.1 2 7.5 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 KKK15097.1 - 0.0054 16.5 4.1 2 8.1 0.0 3.5 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit DUF853 PF05872.7 KKK15097.1 - 0.0067 14.8 0.2 0.056 11.7 0.0 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.1 KKK15097.1 - 0.0075 16.1 0.0 3.9 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KKK15097.1 - 0.008 15.7 0.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KKK15097.1 - 0.0081 15.5 0.9 1.9 7.8 0.1 3.2 2 2 1 3 3 3 1 AAA domain AAA_10 PF12846.2 KKK15097.1 - 0.0094 15.4 0.1 0.16 11.3 0.0 2.8 2 2 0 2 2 2 1 AAA-like domain DUF815 PF05673.8 KKK15097.1 - 0.01 14.8 0.1 0.38 9.6 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KKK15097.1 - 0.01 15.3 0.0 0.64 9.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 KKK15097.1 - 0.01 15.4 6.0 0.17 11.4 0.0 4.2 4 1 0 5 5 4 0 AAA domain DUF3333 PF11812.3 KKK15097.1 - 0.012 15.5 1.8 0.017 15.1 0.0 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF3333) AAA_24 PF13479.1 KKK15097.1 - 0.013 15.0 0.0 0.7 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KKK15097.1 - 0.02 14.1 0.0 4 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KKK15097.1 - 0.023 13.7 3.0 0.19 10.8 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin UPF0079 PF02367.12 KKK15097.1 - 0.024 14.2 0.0 6.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KKK15097.1 - 0.041 14.2 8.1 1.4 9.1 2.9 3.8 4 0 0 4 4 4 0 AAA domain Miro PF08477.8 KKK15097.1 - 0.075 13.5 1.5 1.9 8.9 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein UvrD-helicase PF00580.16 KKK15097.1 - 0.096 11.9 5.2 0.26 10.5 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain GrpE PF01025.14 KKK15097.1 - 0.23 10.9 9.4 0.59 9.6 6.5 1.7 1 0 0 1 1 1 0 GrpE Prefoldin_2 PF01920.15 KKK15097.1 - 0.49 10.1 13.4 1.6 8.5 2.5 3.0 1 1 1 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 KKK15097.1 - 0.6 7.8 6.1 0.85 7.4 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 KKK15097.1 - 1.2 8.0 9.5 2.4 7.0 6.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2968 PF11180.3 KKK15097.1 - 1.4 8.2 10.0 3.4 7.0 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIC PF04977.10 KKK15097.1 - 1.6 8.3 14.2 2.1 7.8 6.9 2.5 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 KKK15097.1 - 2.7 6.9 10.0 4.7 6.1 6.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KKK15097.1 - 3.5 7.1 17.6 0.44 10.1 9.0 1.9 3 0 0 3 3 1 0 IncA protein MutS_V PF00488.16 KKK15098.1 - 4.7e-27 94.9 0.1 1.3e-26 93.4 0.1 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 KKK15098.1 - 2.5e-20 73.1 0.1 7.9e-20 71.5 0.0 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KKK15098.1 - 0.0035 17.4 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV MMgT PF10270.4 KKK15099.1 - 1.4e-24 86.5 0.4 1.5e-24 86.4 0.3 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.14 KKK15100.1 - 1.9e-30 104.4 3.9 3.1e-30 103.7 2.7 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KKK15100.1 - 3.7e-12 46.1 4.5 3.7e-12 46.1 3.2 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 KKK15100.1 - 0.00053 19.9 0.2 0.0016 18.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK15100.1 - 0.00071 20.0 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK15100.1 - 0.0026 17.6 0.3 0.18 11.7 0.2 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YL1 PF05764.8 KKK15100.1 - 0.13 11.8 6.3 0.027 14.1 0.8 1.9 2 0 0 2 2 2 0 YL1 nuclear protein DNA_pol3_a_NII PF11490.3 KKK15100.1 - 3.5 7.2 9.2 0.28 10.8 0.9 2.3 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus II UQ_con PF00179.21 KKK15101.1 - 2.7e-35 120.8 0.0 4.3e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK15101.1 - 0.0022 17.7 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B Sas10 PF09368.5 KKK15102.1 - 6.7e-30 103.0 7.4 6.7e-30 103.0 5.1 3.2 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KKK15102.1 - 1.9e-13 50.3 1.2 7.3e-13 48.5 0.0 2.7 3 0 0 3 3 3 1 Sas10/Utp3/C1D family adh_short PF00106.20 KKK15103.1 - 3.2e-14 53.1 0.0 4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK15103.1 - 9e-09 35.2 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK15103.1 - 2e-05 24.5 0.0 2.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KKK15103.1 - 0.00032 20.1 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK15103.1 - 0.00094 19.2 0.3 0.0019 18.2 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 KKK15103.1 - 0.0015 18.7 0.2 0.0023 18.1 0.1 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 KKK15103.1 - 0.0018 17.3 0.2 0.0031 16.6 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KKK15103.1 - 0.003 17.6 0.7 0.004 17.2 0.5 1.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KKK15103.1 - 0.016 14.0 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 KKK15103.1 - 0.026 14.1 0.3 0.039 13.6 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KKK15103.1 - 0.057 12.4 0.1 0.072 12.0 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 KKK15103.1 - 0.057 13.2 0.0 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 KKK15103.1 - 0.085 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KKK15103.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FA_hydroxylase PF04116.8 KKK15104.1 - 1.8e-13 50.9 11.0 1.8e-13 50.9 7.7 2.4 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily Spt5_N PF11942.3 KKK15104.1 - 3.2 8.4 8.7 5.8 7.6 6.0 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF904 PF06005.7 KKK15104.1 - 6.2 7.1 6.2 2.5 8.4 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Pribosyltran PF00156.22 KKK15105.1 - 1.9e-08 34.0 0.1 6.4e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SLAC1 PF03595.12 KKK15106.1 - 2.3e-75 253.2 49.5 2.6e-75 253.0 34.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel COX14 PF14880.1 KKK15106.1 - 0.13 11.9 0.2 0.13 11.9 0.1 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly PTCB-BRCT PF12738.2 KKK15107.1 - 1.6e-06 27.8 0.2 3e-06 26.9 0.1 1.5 1 1 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KKK15107.1 - 4.1e-05 23.6 0.2 6.5e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nup188 PF10487.4 KKK15108.1 - 3.5e-49 167.5 0.0 6.7e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.16 KKK15109.1 - 2.1e-98 328.4 0.0 7.1e-98 326.6 0.0 1.8 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 KKK15109.1 - 1.8e-57 194.0 0.1 3.4e-56 189.9 0.0 2.6 2 1 1 3 3 3 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 KKK15109.1 - 2.6e-52 177.0 0.0 4.2e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KKK15109.1 - 0.00026 20.4 0.3 0.0011 18.4 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 KKK15109.1 - 0.00057 19.4 0.2 0.0055 16.2 0.0 2.7 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 KKK15109.1 - 0.0049 16.1 0.1 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 KKK15109.1 - 0.017 14.0 0.4 0.071 12.0 0.0 2.2 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase AMP-binding PF00501.23 KKK15110.1 - 6.3e-72 242.2 0.0 1.7e-71 240.8 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK15110.1 - 1.3e-13 51.7 0.2 4.4e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1180 PF06679.7 KKK15111.1 - 9.7 6.0 6.0 7.7 6.3 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Use1 PF09753.4 KKK15112.1 - 4.9e-11 42.5 0.3 8.1e-11 41.8 0.2 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 GldM_N PF12081.3 KKK15112.1 - 0.0076 15.8 0.3 0.0076 15.8 0.2 1.6 2 0 0 2 2 2 1 GldM N-terminal domain DUF3596 PF12167.3 KKK15112.1 - 0.076 12.5 1.0 0.6 9.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3596) Hid1 PF12722.2 KKK15112.1 - 0.21 9.2 4.7 0.26 8.9 3.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF572 PF04502.8 KKK15112.1 - 3.8 6.6 9.3 5.4 6.1 6.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF572) Synaptobrevin PF00957.16 KKK15112.1 - 5.7 6.6 6.1 1.2 8.7 0.2 2.6 2 1 1 3 3 3 0 Synaptobrevin G-alpha PF00503.15 KKK15113.1 - 1.4e-134 448.6 1.0 1.7e-134 448.3 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KKK15113.1 - 1.9e-15 56.5 1.6 2e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KKK15113.1 - 8.1e-05 22.0 0.0 0.00037 19.9 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KKK15113.1 - 0.0014 19.0 0.6 2.8 8.4 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KKK15113.1 - 0.0069 15.5 3.1 0.22 10.6 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KKK15113.1 - 0.0093 15.4 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KKK15113.1 - 0.021 14.2 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KKK15113.1 - 0.026 14.8 0.0 0.063 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 KKK15113.1 - 0.082 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 KKK15113.1 - 0.094 12.6 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KKK15113.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family UCH PF00443.24 KKK15120.1 - 1e-40 139.5 0.0 6.7e-35 120.5 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK15120.1 - 1.3e-12 47.7 0.3 8.2e-12 45.1 0.2 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Porin_3 PF01459.17 KKK15120.1 - 0.14 11.3 3.0 1.7 7.8 0.2 2.3 2 0 0 2 2 2 0 Eukaryotic porin AlaDh_PNT_N PF05222.10 KKK15121.1 - 3.4e-30 104.8 0.0 5.4e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KKK15121.1 - 3e-19 69.2 0.0 4.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KKK15121.1 - 0.075 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Complex1_51K PF01512.12 KKK15128.1 - 1.5e-45 154.6 0.0 2.5e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KKK15128.1 - 4.2e-18 64.2 0.7 8.5e-18 63.2 0.5 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KKK15128.1 - 1e-08 34.8 0.0 2.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 SLBB domain SET PF00856.23 KKK15128.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 SET domain SAPS PF04499.10 KKK15129.1 - 2.1e-78 264.0 0.5 1.8e-77 260.9 0.0 2.0 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein SAPS PF04499.10 KKK15130.1 - 1.6e-127 426.0 0.0 6.7e-126 420.7 0.0 2.2 2 1 0 2 2 2 2 SIT4 phosphatase-associated protein DUF4484 PF14831.1 KKK15130.1 - 1.4 9.0 6.4 0.19 11.8 1.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Afi1 PF07792.7 KKK15132.1 - 1.8e-64 216.1 0.1 3.1e-64 215.3 0.1 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KKK15132.1 - 1.9e-37 127.3 0.0 3.2e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KKK15132.1 - 1.3e-08 33.8 0.4 0.0094 14.4 0.0 3.6 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 KKK15132.1 - 0.021 14.1 0.0 0.068 12.4 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) HNF-1_N PF04814.8 KKK15132.1 - 0.062 13.3 1.1 1.2 9.2 1.1 2.3 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Peripla_BP_6 PF13458.1 KKK15132.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Hep_59 PF07052.6 KKK15135.1 - 1.1e-21 77.1 7.7 1.7e-21 76.5 0.0 3.0 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Chorion_2 PF03964.10 KKK15135.1 - 0.025 15.1 0.6 0.025 15.1 0.4 2.2 2 0 0 2 2 2 0 Chorion family 2 RNB PF00773.14 KKK15136.1 - 2.7e-49 168.2 0.0 2.6e-47 161.6 0.0 2.3 1 1 0 1 1 1 1 RNB domain MARVEL PF01284.18 KKK15137.1 - 0.00057 19.7 14.1 0.0016 18.3 9.9 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF898 PF05987.8 KKK15137.1 - 5.4 5.7 7.6 0.67 8.7 1.7 1.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) FAD_binding_4 PF01565.18 KKK15138.1 - 4.6e-20 71.4 0.8 7.7e-20 70.7 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Cys_Met_Meta_PP PF01053.15 KKK15139.1 - 1.7e-63 214.2 0.0 3.8e-63 213.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KKK15139.1 - 0.00083 18.1 0.0 0.0022 16.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KKK15139.1 - 0.017 14.1 0.0 0.035 13.0 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KKK15139.1 - 0.032 13.2 0.0 2.6 6.9 0.0 2.6 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family GRAB PF10375.4 KKK15143.1 - 6.3e-09 35.0 0.2 1.3e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.16 KKK15143.1 - 0.00014 21.4 49.0 0.013 15.0 11.9 3.2 1 1 2 3 3 3 2 Intermediate filament protein Reo_sigmaC PF04582.7 KKK15143.1 - 0.001 18.3 10.4 0.088 11.9 0.5 2.4 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Tup_N PF08581.5 KKK15143.1 - 0.0016 18.5 2.9 0.0016 18.5 2.0 4.9 2 2 3 5 5 5 1 Tup N-terminal DUF3584 PF12128.3 KKK15143.1 - 0.0034 14.8 44.4 0.0052 14.1 30.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) GAS PF13851.1 KKK15143.1 - 0.0077 15.4 7.6 0.0077 15.4 5.3 3.8 1 1 2 3 3 2 1 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 KKK15143.1 - 0.012 14.9 5.1 0.012 14.9 3.5 4.7 2 1 3 5 5 5 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.3 KKK15143.1 - 0.017 14.8 5.7 0.017 14.8 3.9 4.4 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.13 KKK15143.1 - 0.089 12.5 0.1 0.089 12.5 0.1 5.4 6 1 0 6 6 5 0 Homeobox associated leucine zipper ApoO PF09769.4 KKK15143.1 - 0.14 11.8 13.1 0.088 12.5 0.6 3.6 1 1 2 3 3 3 0 Apolipoprotein O WEMBL PF05701.6 KKK15143.1 - 0.28 9.5 54.4 0.64 8.4 37.7 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF4250 PF14056.1 KKK15143.1 - 0.41 10.4 8.8 0.53 10.0 0.3 3.5 3 1 1 4 4 3 0 Domain of unknown function (DUF4250) DUF1664 PF07889.7 KKK15143.1 - 0.91 9.3 27.2 0.42 10.4 2.3 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) FH2 PF02181.18 KKK15143.1 - 0.95 8.2 33.2 0.42 9.4 6.3 3.2 1 1 2 3 3 3 0 Formin Homology 2 Domain TPR_MLP1_2 PF07926.7 KKK15143.1 - 0.97 9.1 56.4 1.4 8.6 11.8 4.7 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.6 KKK15143.1 - 1.7 9.0 36.1 0.14 12.6 5.4 4.2 2 1 3 5 5 4 0 Syntaxin 6, N-terminal FUSC PF04632.7 KKK15143.1 - 1.8 6.9 20.1 0.76 8.1 5.0 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Spc7 PF08317.6 KKK15143.1 - 3.1 6.3 45.6 0.26 9.8 11.3 2.9 1 1 0 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 KKK15143.1 - 3.2 7.5 16.3 5.4 6.8 1.4 3.3 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KKK15143.1 - 5.3 7.3 19.1 1.2 9.4 0.4 4.8 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Carn_acyltransf PF00755.15 KKK15144.1 - 3.4e-178 593.4 0.0 3.8e-178 593.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.5 KKK15145.1 - 5.5e-30 103.9 0.0 1.4e-29 102.6 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KKK15145.1 - 0.0012 18.8 0.0 0.0053 16.7 0.0 2.1 3 0 0 3 3 3 1 LCCL domain MFS_1 PF07690.11 KKK15146.1 - 2.9e-25 88.7 23.9 2.9e-25 88.7 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PsbN PF02468.10 KKK15146.1 - 2.5 7.7 7.3 5.3 6.7 0.7 3.0 2 1 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF2576 PF10845.3 KKK15147.1 - 0.021 14.0 0.2 0.061 12.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) DUF3573 PF12097.3 KKK15147.1 - 0.33 9.5 1.5 7.1 5.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Striatin PF08232.7 KKK15147.1 - 0.35 11.1 7.7 3.4 7.9 0.5 2.4 2 0 0 2 2 2 0 Striatin family DUF2046 PF09755.4 KKK15147.1 - 0.69 8.7 10.6 0.052 12.4 3.8 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) PEP-utilisers_N PF05524.8 KKK15147.1 - 0.73 9.6 6.4 0.38 10.5 0.9 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal FlxA PF14282.1 KKK15147.1 - 0.81 9.6 20.2 4.7 7.2 0.5 2.5 2 0 0 2 2 2 0 FlxA-like protein DUF641 PF04859.7 KKK15147.1 - 1.2 8.8 6.8 3.3 7.4 1.1 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 KKK15147.1 - 1.4 8.4 11.5 11 5.5 5.7 2.2 2 0 0 2 2 2 0 IncA protein DASH_Spc34 PF08657.5 KKK15147.1 - 1.8 8.1 10.6 2.4 7.7 3.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF2968 PF11180.3 KKK15147.1 - 3 7.1 21.4 0.17 11.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) HOOK PF05622.7 KKK15147.1 - 3.1 5.4 10.5 0.86 7.3 0.1 2.0 2 0 0 2 2 2 0 HOOK protein DUF16 PF01519.11 KKK15147.1 - 3.8 7.7 7.5 3.7 7.8 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 DivIC PF04977.10 KKK15147.1 - 4.2 6.9 13.8 0.11 11.9 0.3 2.4 2 1 0 2 2 2 0 Septum formation initiator DUF2681 PF10883.3 KKK15147.1 - 6.3 7.0 9.1 20 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Exo_endo_phos PF03372.18 KKK15148.1 - 4.7e-20 72.5 0.1 7.5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.1 KKK15148.1 - 7.9e-16 57.5 21.2 2.8e-08 33.3 3.1 2.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KKK15148.1 - 5.9e-15 54.4 7.1 4.5e-10 38.9 1.1 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KKK15148.1 - 8.8e-07 28.1 4.7 0.032 14.2 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KKK15148.1 - 6.8e-05 22.4 10.0 0.019 15.0 0.2 4.4 4 0 0 4 4 4 2 Leucine rich repeat Dynamin_M PF01031.15 KKK15149.1 - 3.4e-114 380.6 0.0 6.3e-114 379.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KKK15149.1 - 1e-54 184.8 0.0 2.7e-54 183.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KKK15149.1 - 1.2e-30 105.2 1.2 2.8e-30 104.0 0.8 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KKK15149.1 - 0.0012 18.8 0.2 0.0097 15.8 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK15149.1 - 0.0081 16.6 0.0 0.027 14.9 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KKK15149.1 - 0.066 12.4 0.1 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B zf-CCHC_4 PF14392.1 KKK15149.1 - 0.07 12.8 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle UAA PF08449.6 KKK15150.1 - 7.8e-76 254.8 19.7 2.5e-74 249.9 13.7 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KKK15150.1 - 4.5e-05 23.1 13.9 4.5e-05 23.1 9.6 3.1 2 2 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KKK15150.1 - 0.00019 20.6 0.8 0.00019 20.6 0.5 1.9 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 KKK15150.1 - 0.002 18.2 5.5 0.002 18.2 3.8 3.4 3 2 1 4 4 4 2 Multidrug resistance efflux transporter Rad17 PF03215.10 KKK15151.1 - 2e-57 195.0 0.0 3e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KKK15151.1 - 0.00022 21.2 0.2 0.0016 18.4 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 KKK15151.1 - 0.013 15.6 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KKK15151.1 - 0.015 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KKK15151.1 - 0.037 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 KKK15151.1 - 0.043 12.7 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KKK15151.1 - 0.047 13.8 0.0 0.37 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 KKK15151.1 - 0.074 13.8 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KKK15151.1 - 0.089 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KKK15151.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KKK15151.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 KKK15151.1 - 0.17 11.4 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ELMO_CED12 PF04727.8 KKK15152.1 - 1.1e-50 171.5 0.1 1.6e-50 170.9 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KKK15152.1 - 7.8e-07 28.9 0.0 2.2e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DUF4257 PF14074.1 KKK15152.1 - 0.14 11.8 0.0 9.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) TOH_N PF12549.3 KKK15153.1 - 0.057 13.0 0.0 0.22 11.1 0.0 2.1 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal A_deaminase PF00962.17 KKK15154.1 - 7.1e-114 380.1 0.0 9.6e-114 379.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3_9 PF14604.1 KKK15155.1 - 1e-28 98.6 4.4 7.4e-16 57.4 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KKK15155.1 - 4.1e-26 90.0 4.6 1.5e-14 53.0 0.4 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KKK15155.1 - 1e-16 60.1 0.2 3.4e-07 29.6 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 KKK15155.1 - 1.6e-09 37.7 0.0 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Sec10 PF07393.6 KKK15157.1 - 1.9e-241 803.2 0.0 2.2e-241 802.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MarR_2 PF12802.2 KKK15157.1 - 0.011 15.3 0.2 1.3 8.6 0.0 3.0 2 0 0 2 2 2 0 MarR family DUF2458 PF10454.4 KKK15157.1 - 0.11 12.3 1.3 1.5 8.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) BNR PF02012.15 KKK15158.1 - 3.7e-08 31.9 35.0 1.4 9.0 0.0 11.9 12 0 0 12 12 12 5 BNR/Asp-box repeat PSII_BNR PF14870.1 KKK15158.1 - 3.6e-06 26.2 4.5 0.02 13.8 0.0 6.1 5 2 2 7 7 7 2 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.11 KKK15158.1 - 0.098 12.2 9.4 0.3 10.7 0.0 5.5 8 0 0 8 8 8 0 Mo-co oxidoreductase dimerisation domain Ytp1 PF10355.4 KKK15160.1 - 4.7e-113 376.8 9.6 6.6e-113 376.4 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KKK15160.1 - 1.5e-20 72.7 10.2 7.5e-19 67.2 1.7 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) DUF3500 PF12006.3 KKK15161.1 - 6.8e-106 353.7 0.0 7.9e-106 353.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) CTP_synth_N PF06418.9 KKK15162.1 - 3.6e-116 387.0 0.2 4.9e-116 386.6 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KKK15162.1 - 9.4e-51 172.0 0.1 2.6e-50 170.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KKK15162.1 - 1.4e-06 27.9 0.0 2.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KKK15162.1 - 0.0021 17.5 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.20 KKK15163.1 - 2.7e-20 72.9 0.5 1.2e-18 67.6 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK15163.1 - 2.7e-07 30.4 0.0 7.5e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK15163.1 - 0.0008 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0160 PF03690.8 KKK15164.1 - 3.2e-118 394.7 0.0 3.7e-118 394.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF3437 PF11919.3 KKK15165.1 - 5.5e-32 109.3 0.0 2e-31 107.5 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) CLASP_N PF12348.3 KKK15165.1 - 1.1e-06 28.1 0.0 0.023 14.0 0.0 3.4 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.17 KKK15165.1 - 0.0017 18.2 0.1 1.2 9.3 0.0 4.6 3 0 0 3 3 3 1 HEAT repeat Adaptin_N PF01602.15 KKK15165.1 - 0.17 10.1 0.0 0.44 8.7 0.0 1.6 2 0 0 2 2 2 0 Adaptin N terminal region V_ATPase_I PF01496.14 KKK15166.1 - 1.2e-297 988.9 0.2 1.4e-297 988.7 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 KKK15166.1 - 0.0055 16.5 0.1 0.015 15.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) DUF3552 PF12072.3 KKK15166.1 - 0.03 13.5 1.5 5.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Serine_rich PF08824.5 KKK15166.1 - 0.04 13.6 1.0 0.19 11.4 0.1 2.1 2 0 0 2 2 2 0 Serine rich protein interaction domain Filament PF00038.16 KKK15166.1 - 0.064 12.7 7.5 2.6 7.4 0.1 2.4 2 1 0 2 2 2 0 Intermediate filament protein YlqD PF11068.3 KKK15166.1 - 0.16 12.0 1.2 2.9 7.9 0.2 2.5 2 0 0 2 2 2 0 YlqD protein CheZ PF04344.8 KKK15166.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.4 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ FliD_C PF07195.7 KKK15166.1 - 0.22 10.7 3.1 0.83 8.8 0.3 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Prefoldin_2 PF01920.15 KKK15166.1 - 0.37 10.5 2.9 1.2 8.8 0.2 2.7 3 0 0 3 3 3 0 Prefoldin subunit DUF869 PF05911.6 KKK15166.1 - 0.39 8.8 4.5 2 6.5 3.1 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) IncA PF04156.9 KKK15166.1 - 1.3 8.5 5.0 0.94 9.0 1.3 2.1 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 KKK15166.1 - 3.8 7.0 7.0 0.41 10.1 0.3 2.8 3 0 0 3 3 3 0 Septum formation initiator BioY PF02632.9 KKK15166.1 - 7.1 6.2 13.2 0.23 11.1 0.3 2.8 3 0 0 3 3 3 0 BioY family Peptidase_M24 PF00557.19 KKK15167.1 - 2.9e-43 147.8 0.1 3.9e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 BLVR PF06375.6 KKK15167.1 - 1.6 8.5 7.3 11 5.8 2.7 2.4 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Glyco_transf_54 PF04666.8 KKK15168.1 - 4.7e-11 41.9 0.5 0.00011 21.1 0.0 2.9 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glucos_trans_II PF14264.1 KKK15168.1 - 0.0061 15.6 0.6 0.0061 15.6 0.4 1.6 2 0 0 2 2 2 1 Glucosyl transferase GtrII DUF4131 PF13567.1 KKK15168.1 - 6 6.2 6.8 6 6.2 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF543 PF04418.7 KKK15169.1 - 1.7e-26 91.9 0.0 1.8e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.4 KKK15170.1 - 6.2e-69 232.0 0.0 6.2e-69 232.0 0.0 2.9 4 0 0 4 4 4 1 Urb2/Npa2 family Copper-fist PF00649.13 KKK15171.1 - 1.6e-19 68.7 0.3 5.7e-19 67.0 0.2 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain Transp_cyt_pur PF02133.10 KKK15172.1 - 1.8e-150 501.3 32.4 2e-150 501.1 22.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RVT_1 PF00078.22 KKK15173.1 - 5.1e-08 32.5 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SnoaL PF07366.7 KKK15174.1 - 6.9e-05 22.4 0.0 0.00017 21.1 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KKK15174.1 - 0.00083 19.7 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain Med4 PF10018.4 KKK15175.1 - 2.8e-51 173.6 0.3 5.4e-51 172.6 0.0 1.5 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 adh_short PF00106.20 KKK15176.1 - 1.5e-29 103.0 1.1 2.1e-29 102.5 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK15176.1 - 1.9e-28 99.8 0.0 2.4e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK15176.1 - 9.1e-12 45.0 0.8 1.4e-11 44.3 0.6 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KKK15176.1 - 0.014 14.5 0.2 0.074 12.1 0.1 2.0 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 KKK15176.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KKK15176.1 - 0.083 12.3 0.6 0.23 10.8 0.4 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CPSase_L_chain PF00289.17 KKK15176.1 - 0.11 12.5 0.2 0.62 10.1 0.1 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain FAD_binding_3 PF01494.14 KKK15177.1 - 4.3e-10 39.1 0.0 1.5e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK15177.1 - 2e-06 26.9 0.0 0.034 13.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK15177.1 - 0.014 14.2 0.1 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Imm44 PF15584.1 KKK15177.1 - 0.031 14.1 0.7 9.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 44 HI0933_like PF03486.9 KKK15177.1 - 0.14 10.5 0.0 0.92 7.9 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein EthD PF07110.6 KKK15178.1 - 1.4e-21 77.1 0.4 1.8e-21 76.8 0.3 1.1 1 0 0 1 1 1 1 EthD domain ketoacyl-synt PF00109.21 KKK15179.1 - 2.1e-67 227.2 0.1 3.9e-67 226.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK15179.1 - 3.6e-50 171.1 0.1 9.8e-49 166.3 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KKK15179.1 - 2.2e-32 111.3 0.9 6.8e-32 109.8 0.6 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KKK15179.1 - 6.3e-11 42.3 0.4 1.9e-10 40.8 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1772 PF08592.6 KKK15180.1 - 4.7e-24 84.7 8.4 5.7e-24 84.4 5.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4149 PF13664.1 KKK15180.1 - 0.39 10.8 3.2 0.58 10.2 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Lactamase_B PF00753.22 KKK15181.1 - 2.7e-25 89.1 3.2 3.8e-25 88.6 2.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK15181.1 - 6.3e-05 22.5 1.3 0.00012 21.6 0.9 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain AflR PF08493.5 KKK15182.1 - 4.2e-26 91.5 0.6 1.1e-25 90.2 0.0 1.8 2 0 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.13 KKK15182.1 - 3.5e-07 30.0 8.9 6.1e-07 29.2 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M14 PF00246.19 KKK15183.1 - 7.9e-69 232.3 0.0 1.2e-68 231.7 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Ribosomal_60s PF00428.14 KKK15183.1 - 0.0037 17.6 5.2 0.0069 16.7 3.6 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 KKK15183.1 - 1.5 7.5 3.8 2.2 7.0 2.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mito_carr PF00153.22 KKK15207.1 - 3e-62 206.3 4.5 2.1e-21 75.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RTA1 PF04479.8 KKK15208.1 - 2.8e-45 154.5 2.2 4.1e-45 154.0 1.5 1.1 1 0 0 1 1 1 1 RTA1 like protein UQ_con PF00179.21 KKK15209.1 - 9.5e-44 148.2 0.0 1.1e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KKK15209.1 - 0.25 11.2 1.9 0.57 10.0 1.3 1.8 1 1 0 1 1 1 0 RWD domain DUF4237 PF14021.1 KKK15211.1 - 4.2e-33 113.4 0.1 1.1e-32 112.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4237) ADH_N PF08240.7 KKK15212.1 - 1.3e-06 28.0 0.0 3.4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK15212.1 - 0.00073 19.0 0.1 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CDO_I PF05995.7 KKK15213.1 - 7.9e-31 106.5 0.4 2.6e-22 78.8 0.8 3.0 2 1 0 2 2 2 2 Cysteine dioxygenase type I DUF1637 PF07847.7 KKK15213.1 - 4.2e-05 22.9 0.1 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) MMR_HSR1 PF01926.18 KKK15214.1 - 1.4e-18 66.8 0.1 3.3e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 KKK15214.1 - 1.6e-18 66.2 0.0 4.1e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KKK15214.1 - 4.2e-10 39.1 0.1 2.5e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KKK15214.1 - 4.8e-05 22.8 0.6 0.55 9.6 0.0 3.9 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KKK15214.1 - 0.0003 20.6 0.4 0.048 13.4 0.0 2.2 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KKK15214.1 - 0.0057 15.4 0.1 0.011 14.4 0.1 1.5 1 0 0 1 1 1 1 ArgK protein Arf PF00025.16 KKK15214.1 - 0.027 13.7 0.2 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 KKK15214.1 - 0.03 14.8 0.1 0.077 13.4 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein Thymidylat_synt PF00303.14 KKK15215.1 - 7.9e-107 356.2 0.0 1e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase TGT PF01702.13 KKK15215.1 - 8.7e-79 264.1 0.0 2.4e-78 262.6 0.0 1.7 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase zf-AN1 PF01428.11 KKK15216.1 - 2e-18 65.9 11.4 3.1e-12 46.1 4.7 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 KKK15216.1 - 1.4 9.2 9.4 0.067 13.4 2.2 2.1 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain C1_4 PF07975.7 KKK15216.1 - 5 7.2 8.7 0.81 9.7 2.5 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain Hist_deacetyl PF00850.14 KKK15217.1 - 9.7e-31 107.1 0.0 1.3e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Nop14 PF04147.7 KKK15219.1 - 2.7 5.8 10.1 3.4 5.4 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 KKK15221.1 - 1.2e-27 96.5 27.4 1.4e-27 96.3 19.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-H2C2_2 PF13465.1 KKK15225.1 - 5.3e-11 42.2 7.4 6e-05 23.1 0.1 3.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KKK15225.1 - 3.9e-05 23.7 24.7 0.0058 16.9 4.6 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK15225.1 - 0.0055 16.9 17.5 1.3 9.4 2.9 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger Bunya_G2 PF03563.8 KKK15225.1 - 0.044 12.6 3.4 0.07 12.0 2.4 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_6 PF13912.1 KKK15225.1 - 0.75 9.7 7.5 1.7 8.6 0.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger CP2 PF04516.10 KKK15226.1 - 1e-91 306.2 0.0 1.7e-91 305.5 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Clathrin PF00637.15 KKK15227.1 - 2.7e-21 75.6 0.3 1.5e-18 66.7 0.1 3.2 2 1 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 KKK15227.1 - 5.3e-06 26.1 0.9 0.0072 16.1 0.2 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.1 KKK15227.1 - 0.01 16.0 0.3 0.19 12.0 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain Vps39_1 PF10366.4 KKK15227.1 - 0.016 15.1 0.1 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.1 KKK15227.1 - 0.048 13.3 0.8 0.1 12.3 0.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain TPR_2 PF07719.12 KKK15227.1 - 0.061 13.2 0.1 2 8.5 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK15227.1 - 0.14 12.0 0.7 8.4 6.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 KKK15227.1 - 0.15 11.8 1.3 0.32 10.8 0.9 1.5 1 0 0 1 1 1 0 Ring finger domain DUF155 PF02582.9 KKK15228.1 - 1.1e-43 149.1 0.0 1.5e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ribonuclease_T2 PF00445.13 KKK15229.1 - 3.9e-48 163.5 1.0 7.3e-48 162.6 0.7 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family Nodulin-like PF06813.8 KKK15230.1 - 1.5e-17 63.6 1.8 3.7e-17 62.4 1.3 1.7 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KKK15230.1 - 1.7e-17 63.1 36.1 2.7e-15 55.9 21.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Serinc PF03348.10 KKK15231.1 - 4.9e-169 562.5 7.5 6e-169 562.2 5.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3492 PF11997.3 KKK15232.1 - 0.0019 17.7 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) SynMuv_product PF06047.6 KKK15232.1 - 0.23 11.2 0.0 0.5 10.1 0.0 1.5 1 0 0 1 1 1 0 Ras-induced vulval development antagonist Lactamase_B PF00753.22 KKK15233.1 - 3.7e-18 65.8 1.5 4.8e-18 65.5 1.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK15233.1 - 0.087 12.3 1.7 0.12 11.9 1.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SLAC1 PF03595.12 KKK15234.1 - 3.8e-103 344.6 55.2 4.3e-103 344.4 38.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Rhodanese PF00581.15 KKK15235.1 - 8.7e-17 61.4 0.0 3e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF202 PF02656.10 KKK15236.1 - 6.4e-20 71.1 0.3 1.6e-19 69.9 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF202) UCR_6-4kD PF08997.5 KKK15236.1 - 0.29 10.8 1.4 0.49 10.1 0.1 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Zn_clus PF00172.13 KKK15237.1 - 4.6e-11 42.4 8.1 8.8e-11 41.5 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK15237.1 - 4.6e-11 42.0 0.7 1.2e-10 40.7 0.3 1.7 1 1 0 2 2 2 1 Fungal specific transcription factor domain DUF2853 PF11015.3 KKK15237.1 - 0.075 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) APH PF01636.18 KKK15238.1 - 1.9e-05 24.5 0.0 0.00015 21.6 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK15238.1 - 0.0035 16.9 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase FKBP_C PF00254.23 KKK15239.1 - 2.1e-33 114.2 0.0 2.6e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_tranf_2_3 PF13641.1 KKK15240.1 - 1.1e-31 110.3 0.0 2.1e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KKK15240.1 - 2.7e-16 59.8 6.8 2.7e-16 59.8 4.7 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KKK15240.1 - 5.1e-12 45.7 0.0 7.6e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KKK15240.1 - 1.3e-06 27.8 0.0 2.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF3759 PF12585.3 KKK15241.1 - 2.3e-41 139.6 6.4 2.7e-41 139.3 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Dabb PF07876.7 KKK15241.1 - 0.032 14.6 0.2 0.056 13.8 0.2 1.5 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Herpes_Helicase PF02689.9 KKK15241.1 - 0.13 9.9 0.0 0.14 9.9 0.0 1.0 1 0 0 1 1 1 0 Helicase Aa_trans PF01490.13 KKK15242.1 - 3.1e-21 75.3 33.5 3.9e-21 75.0 23.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2633 PF11119.3 KKK15242.1 - 9 6.1 6.9 29 4.4 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) MFS_1 PF07690.11 KKK15243.1 - 5.1e-29 101.0 26.0 5.1e-29 101.0 18.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Spherulin4 PF12138.3 KKK15244.1 - 2.1e-66 223.9 1.7 2.4e-66 223.7 1.2 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Synaptobrevin PF00957.16 KKK15244.1 - 0.026 14.1 0.3 1.2 8.7 0.4 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF1510 PF07423.6 KKK15244.1 - 0.1 11.9 0.3 7.2 5.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Lactamase_B PF00753.22 KKK15245.1 - 4.8e-21 75.3 1.3 6.7e-21 74.8 0.9 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK15245.1 - 0.036 13.6 0.1 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.9 KKK15246.1 - 3.7e-06 26.9 0.0 4.2e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK15246.1 - 0.00088 19.0 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KKK15246.1 - 0.0019 17.1 0.3 0.0034 16.3 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KKK15246.1 - 0.01 15.9 0.1 0.036 14.1 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK15246.1 - 0.091 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK15246.1 - 0.17 10.7 1.4 0.33 9.8 0.2 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein Epimerase PF01370.16 KKK15247.1 - 2.2e-35 122.1 0.0 5.6e-35 120.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KKK15247.1 - 8.4e-17 60.8 0.0 1.7e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KKK15247.1 - 4.5e-08 32.1 0.1 1.5e-06 27.1 0.1 2.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KKK15247.1 - 2.5e-07 29.9 0.0 6.6e-07 28.4 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KKK15247.1 - 5e-06 25.6 0.0 0.00016 20.7 0.0 2.9 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KKK15247.1 - 0.00021 21.2 0.0 0.00043 20.2 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK15247.1 - 0.00034 20.3 0.0 0.0007 19.3 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK15247.1 - 0.014 15.4 0.1 0.8 9.6 0.0 2.8 3 0 0 3 3 3 0 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 KKK15247.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Spherulin4 PF12138.3 KKK15248.1 - 1.1e-62 211.7 0.0 1.2e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Sugar_tr PF00083.19 KKK15250.1 - 1.1e-77 261.5 28.2 1.3e-77 261.3 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK15250.1 - 3.3e-17 62.2 25.2 3.3e-17 62.2 17.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KKK15250.1 - 1.8e-07 29.8 32.4 4.6e-05 21.9 0.7 4.1 3 1 1 4 4 4 4 MFS/sugar transport protein 7TM_GPCR_Sra PF02117.11 KKK15250.1 - 0.012 14.2 1.2 0.025 13.1 0.1 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sra Sugar_tr PF00083.19 KKK15252.1 - 1.3e-88 297.6 18.0 1.5e-88 297.3 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK15252.1 - 4.6e-31 107.8 36.1 4.4e-29 101.2 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK15252.1 - 4.5e-06 25.3 2.2 4.5e-06 25.3 1.6 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KKK15252.1 - 3e-05 22.4 4.3 3e-05 22.4 3.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FTO_CTD PF12934.2 KKK15252.1 - 0.14 11.7 0.1 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 FTO C-terminal domain NfeD PF01957.13 KKK15252.1 - 0.72 9.9 7.9 7.5 6.6 1.3 3.0 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding DUF2371 PF10177.4 KKK15252.1 - 3 7.7 8.4 1.4 8.7 3.9 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF427 PF04248.7 KKK15253.1 - 1.7e-27 94.9 0.2 1.8e-27 94.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DUF1330 PF07045.6 KKK15253.1 - 0.27 11.1 1.3 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) CFEM PF05730.6 KKK15254.1 - 0.004 16.9 12.0 0.024 14.4 8.3 2.2 1 1 0 1 1 1 1 CFEM domain VSG_B PF13206.1 KKK15254.1 - 0.4 9.7 3.8 0.45 9.5 2.7 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF2156 PF09924.4 KKK15256.1 - 4.1e-30 104.6 0.0 5.8e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) Glyco_hydro_45 PF02015.11 KKK15257.1 - 1.7e-17 64.1 16.6 1.7e-17 64.1 11.5 2.3 1 1 2 3 3 3 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 KKK15257.1 - 1.8e-14 53.0 8.6 6.8e-14 51.2 6.0 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 KKK15257.1 - 5.1e-12 46.2 0.1 1.7e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KKK15257.1 - 5.5e-11 42.7 0.2 1.1e-10 41.7 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DPBB_1 PF03330.13 KKK15257.1 - 2.2e-07 30.7 0.4 2.2e-07 30.7 0.3 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Lipase_GDSL_3 PF14606.1 KKK15257.1 - 0.0022 17.7 0.0 0.37 10.5 0.0 2.3 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF3018 PF11455.3 KKK15257.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) Mucin PF01456.12 KKK15257.1 - 0.24 11.1 48.5 0.65 9.7 33.6 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Zn_clus PF00172.13 KKK15258.1 - 8.3e-10 38.4 12.7 8.3e-10 38.4 8.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 KKK15259.1 - 1e-83 279.6 47.9 1.1e-45 155.3 9.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KKK15259.1 - 2e-38 131.7 0.0 1.4e-18 67.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KKK15259.1 - 5e-30 103.1 3.8 2.1e-27 94.8 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter AAA_25 PF13481.1 KKK15259.1 - 5.8e-07 29.1 0.2 0.0037 16.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 KKK15259.1 - 9.3e-07 28.1 25.7 0.00012 21.2 6.3 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.1 KKK15259.1 - 1.1e-05 25.5 0.1 0.051 13.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK15259.1 - 5.7e-05 23.1 0.5 0.015 15.3 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KKK15259.1 - 0.00057 20.2 0.1 1.8 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK15259.1 - 0.00075 20.3 0.0 1.8 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KKK15259.1 - 0.00098 18.6 1.1 0.37 10.2 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.1 KKK15259.1 - 0.0016 18.4 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KKK15259.1 - 0.0016 17.6 0.1 0.0073 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KKK15259.1 - 0.0017 17.8 0.4 0.076 12.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KKK15259.1 - 0.0018 18.2 1.5 0.53 10.2 0.4 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KKK15259.1 - 0.0061 16.4 0.1 1.5 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK15259.1 - 0.014 15.1 1.2 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 KKK15259.1 - 0.028 13.9 0.8 1.6 8.1 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KKK15259.1 - 0.039 13.6 1.5 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 KKK15259.1 - 0.045 14.2 0.0 3.2 8.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KKK15259.1 - 0.068 13.3 0.1 14 5.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 KKK15259.1 - 0.11 12.4 0.1 0.97 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KKK15259.1 - 0.12 11.7 0.4 12 5.2 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain DUF805 PF05656.9 KKK15259.1 - 0.17 11.6 10.0 2.1 8.1 1.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) UPF0079 PF02367.12 KKK15259.1 - 0.23 11.0 0.8 7.3 6.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KKK15259.1 - 0.31 10.6 0.0 33 4.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Fungal_trans_2 PF11951.3 KKK15283.1 - 1.9e-07 30.0 0.5 2.1e-07 29.8 0.0 1.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain G_glu_transpept PF01019.16 KKK15284.1 - 4.1e-155 517.1 0.2 5.4e-155 516.7 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TPP_enzyme_N PF02776.13 KKK15284.1 - 7.8e-38 129.6 0.0 1.7e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ADH_N PF08240.7 KKK15284.1 - 1.4e-28 98.8 7.2 3.3e-28 97.5 5.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK15284.1 - 6.5e-18 64.5 1.0 1.8e-17 63.0 0.4 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.17 KKK15284.1 - 7.9e-17 61.2 0.0 1.8e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KKK15284.1 - 9.1e-17 61.0 0.1 2.7e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ADH_zinc_N_2 PF13602.1 KKK15284.1 - 0.00088 20.1 0.5 0.0034 18.2 0.3 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AATase PF07247.7 KKK15285.1 - 5.2e-05 21.9 0.0 0.00025 19.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KKK15285.1 - 0.025 13.4 0.0 0.049 12.4 0.0 1.5 1 0 0 1 1 1 0 Condensation domain HhH-GPD PF00730.20 KKK15287.1 - 1.6e-07 31.5 0.0 8.2e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DIL PF01843.14 KKK15288.1 - 2.3e-19 69.2 0.5 8.9e-12 44.8 0.1 2.7 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 KKK15288.1 - 4.4e-12 46.1 0.2 1.3e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KKK15288.1 - 1.3e-10 40.5 0.4 1.1e-05 24.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KKK15288.1 - 2.2e-08 34.3 0.1 5.7e-05 23.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK15288.1 - 3.5e-08 33.4 0.0 1.1e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK15288.1 - 2.7e-05 23.9 0.5 0.0034 17.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat DUF2722 PF10846.3 KKK15289.1 - 0.0041 16.2 15.3 0.057 12.4 10.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) RabGAP-TBC PF00566.13 KKK15290.1 - 2.3e-33 115.4 0.1 5.6e-33 114.2 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Fructosamin_kin PF03881.9 KKK15290.1 - 0.047 12.6 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Mo25 PF08569.6 KKK15291.1 - 1e-132 442.2 0.1 1.2e-132 442.0 0.1 1.0 1 0 0 1 1 1 1 Mo25-like DLIC PF05783.6 KKK15291.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Methyltransf_31 PF13847.1 KKK15292.1 - 6.6e-11 42.0 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KKK15292.1 - 1.3e-08 34.3 0.1 2.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KKK15292.1 - 7e-08 33.0 0.0 1.7e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK15292.1 - 8e-08 32.6 0.0 1.7e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK15292.1 - 3.8e-06 26.9 0.0 7.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK15292.1 - 1.3e-05 24.6 0.1 2.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KKK15292.1 - 8.3e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK15292.1 - 0.00023 21.4 0.0 0.00052 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KKK15292.1 - 0.0024 16.6 0.0 0.0059 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 KKK15292.1 - 0.0096 16.3 0.0 0.028 14.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KKK15292.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.9 KKK15292.1 - 0.027 13.6 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Met_10 PF02475.11 KKK15292.1 - 0.041 13.4 0.2 0.082 12.4 0.1 1.4 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.15 KKK15292.1 - 0.041 12.9 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KKK15292.1 - 0.049 13.1 0.1 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KKK15292.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.11 KKK15292.1 - 0.08 11.8 0.1 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.1 KKK15292.1 - 0.11 13.3 0.0 0.27 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cir_N PF10197.4 KKK15293.1 - 0.00094 19.1 7.1 0.00094 19.1 4.9 3.7 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.24 KKK15294.1 - 2.7e-55 186.1 0.1 4.5e-38 130.4 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KKK15294.1 - 6.8e-13 48.3 0.0 2.2e-12 46.7 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 KKK15294.1 - 4.8e-10 38.9 0.2 8.4e-09 34.9 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 KKK15294.1 - 7.7e-10 39.0 0.2 0.00061 19.9 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK15294.1 - 1.3e-07 32.4 0.4 0.0039 17.9 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_2 PF07724.9 KKK15294.1 - 1.6e-07 31.4 0.2 3.3e-05 23.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KKK15294.1 - 1.9e-07 31.0 0.1 0.03 14.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KKK15294.1 - 3.3e-07 30.4 0.0 0.0037 17.2 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 KKK15294.1 - 3.9e-07 30.4 0.1 0.0063 16.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 KKK15294.1 - 1e-06 28.1 0.1 0.0047 16.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK15294.1 - 1.2e-06 28.3 0.0 0.0012 18.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KKK15294.1 - 2e-06 27.0 0.0 0.037 13.0 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK15294.1 - 2e-06 27.4 1.7 0.024 14.3 0.0 3.7 4 0 0 4 4 4 2 Part of AAA domain AAA_33 PF13671.1 KKK15294.1 - 2.1e-06 27.6 0.0 0.048 13.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 KKK15294.1 - 5.3e-06 25.4 0.0 0.022 13.4 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus Arch_ATPase PF01637.13 KKK15294.1 - 1.2e-05 25.2 1.2 7.4 6.1 0.0 4.2 3 1 1 4 4 4 0 Archaeal ATPase AAA_25 PF13481.1 KKK15294.1 - 2.9e-05 23.5 1.1 0.29 10.5 0.0 3.7 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.17 KKK15294.1 - 3.5e-05 23.9 0.0 0.089 12.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.1 KKK15294.1 - 5.5e-05 22.8 0.8 0.12 11.9 0.1 3.0 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KKK15294.1 - 8.3e-05 21.7 0.0 0.3 10.1 0.0 2.9 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 KKK15294.1 - 0.00015 21.2 0.1 0.047 13.1 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein KaiC PF06745.8 KKK15294.1 - 0.00027 20.1 1.1 0.03 13.4 0.1 3.0 2 1 0 3 3 3 1 KaiC AAA_28 PF13521.1 KKK15294.1 - 0.0018 18.2 0.0 0.82 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KKK15294.1 - 0.0028 17.9 0.2 0.013 15.7 0.1 2.1 2 0 0 2 2 1 1 ABC transporter Parvo_NS1 PF01057.12 KKK15294.1 - 0.0035 16.2 0.1 0.4 9.5 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 KTI12 PF08433.5 KKK15294.1 - 0.0066 15.6 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_11 PF13086.1 KKK15294.1 - 0.0097 15.4 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KKK15294.1 - 0.011 15.2 0.1 0.57 9.6 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.11 KKK15294.1 - 0.012 14.8 0.7 1.5 7.9 0.0 2.7 3 0 0 3 3 2 0 PhoH-like protein Sigma54_activ_2 PF14532.1 KKK15294.1 - 0.012 15.6 0.0 10 6.1 0.0 3.0 3 1 0 3 3 2 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 KKK15294.1 - 0.014 14.8 0.0 0.068 12.6 0.0 2.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 KKK15294.1 - 0.018 14.7 0.0 4.8 6.8 0.0 3.1 3 1 0 3 3 2 0 NACHT domain AAA_3 PF07726.6 KKK15294.1 - 0.026 14.1 0.0 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IPT PF01745.11 KKK15294.1 - 0.026 13.6 0.0 0.56 9.3 0.0 2.7 2 1 1 3 3 3 0 Isopentenyl transferase UPF0079 PF02367.12 KKK15294.1 - 0.046 13.3 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 KKK15294.1 - 0.06 12.2 0.3 1.6 7.5 0.1 2.6 3 0 0 3 3 2 0 NB-ARC domain Pkinase PF00069.20 KKK15295.1 - 2.6e-33 115.2 0.0 3.5e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15295.1 - 6e-12 45.1 0.0 1.5e-11 43.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Rtt106 PF08512.7 KKK15296.1 - 1.3e-27 95.6 0.1 4.9e-27 93.7 0.1 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF1379 PF07126.7 KKK15296.1 - 0.036 13.4 0.9 0.81 9.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1379) Vfa1 PF08432.5 KKK15296.1 - 0.78 9.7 7.8 1.6 8.7 5.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.8 KKK15296.1 - 2.1 6.9 11.3 3.4 6.3 7.8 1.3 1 0 0 1 1 1 0 Paf1 Nop25 PF09805.4 KKK15296.1 - 9.8 6.2 14.0 20 5.2 9.7 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) APH PF01636.18 KKK15298.1 - 3e-34 118.7 0.0 1.6e-32 113.1 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KKK15298.1 - 9.1e-06 25.0 0.1 1.6e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KKK15298.1 - 0.001 18.4 0.0 0.16 11.3 0.0 2.4 2 1 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 KKK15298.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KKK15298.1 - 0.0044 16.0 0.0 1.2 8.0 0.0 2.5 2 1 0 2 2 2 2 Fructosamine kinase DUF1679 PF07914.6 KKK15298.1 - 0.029 13.0 0.0 0.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Aa_trans PF01490.13 KKK15299.1 - 2.4e-70 237.1 19.0 2.8e-70 236.8 13.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KKK15299.1 - 2.5e-05 23.3 4.3 2.5e-05 23.3 3.0 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF3321 PF11968.3 KKK15300.1 - 2.4e-94 315.0 0.0 3e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KKK15300.1 - 0.00034 20.3 0.0 0.00097 18.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KKK15300.1 - 0.027 14.1 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase CLTH PF10607.4 KKK15301.1 - 1.5e-35 122.0 0.0 2.9e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DKCLD PF08068.7 KKK15302.1 - 2.6e-29 100.9 0.6 1.1e-28 98.9 0.0 2.3 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 KKK15302.1 - 7.2e-24 84.6 0.2 2e-21 76.6 0.1 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KKK15302.1 - 6.5e-21 73.8 1.1 1.4e-20 72.7 0.8 1.6 1 0 0 1 1 1 1 PUA domain DER1 PF04511.10 KKK15302.1 - 9e-14 51.4 0.6 1.2e-12 47.7 0.0 2.1 1 1 1 2 2 2 1 Der1-like family Med19 PF10278.4 KKK15302.1 - 2.4 7.8 17.5 4.5 6.9 12.1 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PDT PF00800.13 KKK15303.1 - 2.9e-67 225.7 0.1 4.7e-67 225.0 0.1 1.3 1 0 0 1 1 1 1 Prephenate dehydratase eRF1_2 PF03464.10 KKK15304.1 - 5.3e-47 159.4 0.1 8.6e-47 158.7 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KKK15304.1 - 1.6e-39 134.6 0.5 3.2e-39 133.7 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KKK15304.1 - 2.6e-28 98.2 0.0 4.5e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 KKK15304.1 - 0.081 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HMG_CoA_synt_N PF01154.12 KKK15304.1 - 0.17 11.4 1.0 0.35 10.3 0.6 1.7 1 1 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal SMI1_KNR4 PF09346.5 KKK15305.1 - 1.1e-35 122.4 0.0 1.8e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Thioredoxin PF00085.15 KKK15306.1 - 2.3e-05 23.9 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Glypican PF01153.14 KKK15306.1 - 0.38 9.3 3.7 0.5 8.8 2.6 1.2 1 0 0 1 1 1 0 Glypican PGA2 PF07543.7 KKK15306.1 - 1.5 8.6 5.3 2.5 7.9 3.7 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 UAA PF08449.6 KKK15307.1 - 6.1e-11 41.7 16.6 7.7e-11 41.4 11.5 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KKK15307.1 - 8.8e-10 38.4 5.4 8.8e-10 38.4 3.8 2.6 2 2 0 2 2 2 1 Triose-phosphate Transporter family Herpes_LMP1 PF05297.6 KKK15307.1 - 0.00092 18.2 2.7 0.0013 17.7 1.8 1.1 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) PHO4 PF01384.15 KKK15307.1 - 0.0049 15.5 3.1 0.0049 15.5 2.2 2.4 2 1 1 3 3 3 1 Phosphate transporter family EamA PF00892.15 KKK15307.1 - 0.01 15.8 5.0 0.01 15.8 3.5 2.3 2 0 0 2 2 2 0 EamA-like transporter family DUF2431 PF10354.4 KKK15308.1 - 1.1e-40 139.2 0.0 3e-29 102.1 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 KKK15308.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Nucleoplasmin PF03066.10 KKK15308.1 - 0.09 12.2 11.2 0.71 9.3 3.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 KKK15308.1 - 0.92 7.4 9.6 0.35 8.8 2.1 2.1 2 0 0 2 2 2 0 CDC45-like protein TRAP_alpha PF03896.11 KKK15308.1 - 0.93 8.4 6.6 1.5 7.7 1.6 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TLP-20 PF06088.6 KKK15308.1 - 2.1 7.9 10.2 0.51 10.0 0.4 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) dsrm PF00035.20 KKK15308.1 - 4.2 8.0 0.0 4.2 8.0 0.0 3.8 3 1 0 3 3 3 0 Double-stranded RNA binding motif PBP1_TM PF14812.1 KKK15308.1 - 6 7.2 16.7 1.7 9.0 3.8 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 KKK15308.1 - 8.3 5.9 13.6 5.4 6.5 3.6 2.7 3 0 0 3 3 3 0 Sigma-70, non-essential region GHMP_kinases_N PF00288.21 KKK15309.1 - 1.4e-13 50.6 0.0 3e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KKK15309.1 - 0.00014 22.0 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Ribosomal_L23eN PF03939.8 KKK15310.1 - 2.2e-23 82.0 8.6 2.2e-23 82.0 6.0 1.7 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KKK15310.1 - 2.6e-17 62.5 2.8 6.3e-17 61.2 1.9 1.7 1 1 0 1 1 1 1 Ribosomal protein L23 PNRC PF15365.1 KKK15311.1 - 3.5e-07 30.1 16.2 9.8e-07 28.6 2.6 4.2 3 0 0 3 3 3 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 KKK15312.1 - 1.1e-29 102.3 8.8 1.4e-29 102.0 6.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KKK15312.1 - 4.1e-13 48.9 6.6 5.7e-13 48.5 4.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KKK15312.1 - 9.8e-07 28.5 8.4 3.2e-06 26.8 5.8 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK15312.1 - 0.00021 20.8 5.2 0.0016 18.0 3.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK15312.1 - 0.0045 16.6 5.0 0.49 10.1 3.6 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK15312.1 - 0.019 14.9 8.6 0.34 10.9 6.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KKK15312.1 - 0.69 9.6 4.8 13 5.5 3.3 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 KKK15312.1 - 2.9 7.6 8.3 29 4.4 5.7 2.3 1 1 0 1 1 1 0 zinc-RING finger domain CorA PF01544.13 KKK15313.1 - 3e-42 144.6 0.0 5.3e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Spt20 PF12090.3 KKK15314.1 - 5.6e-51 172.4 1.4 5.6e-51 172.4 1.0 5.7 4 2 0 4 4 4 1 Spt20 family Hexapep PF00132.19 KKK15316.1 - 4e-10 38.7 5.0 6.5e-06 25.4 0.5 3.1 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KKK15316.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain GTP_EFTU PF00009.22 KKK15316.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Hexapep_2 PF14602.1 KKK15316.1 - 0.18 11.4 8.0 0.1 12.1 0.7 3.0 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase Uds1 PF15456.1 KKK15326.1 - 7.7e-45 151.8 5.7 7.7e-45 151.8 4.0 6.2 3 1 2 5 5 5 1 Up-regulated During Septation DUF1843 PF08898.5 KKK15326.1 - 0.014 15.4 1.2 0.014 15.4 0.9 6.8 6 1 2 8 8 8 0 Domain of unknown function (DUF1843) Rnk_N PF14760.1 KKK15326.1 - 0.52 10.4 15.5 3.5 7.7 0.3 5.7 5 0 0 5 5 5 0 Rnk N-terminus Tropomyosin_1 PF12718.2 KKK15326.1 - 1 9.1 84.2 0.057 13.2 4.3 7.0 4 1 2 6 6 6 0 Tropomyosin like Myosin_tail_1 PF01576.14 KKK15326.1 - 5.8 4.4 80.7 0.048 11.3 9.2 4.7 2 1 1 4 4 4 0 Myosin tail FlxA PF14282.1 KKK15326.1 - 8.7 6.3 49.9 0.22 11.4 3.4 6.4 3 1 3 7 7 7 0 FlxA-like protein MFS_1 PF07690.11 KKK15327.1 - 5.3e-12 45.1 15.8 5.9e-12 44.9 11.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KKK15328.1 - 1.5e-06 27.1 0.2 1.9e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15328.1 - 0.0072 16.2 3.2 0.0072 16.2 2.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ICMT PF04140.9 KKK15329.1 - 2.8e-09 37.0 4.5 5.4e-07 29.7 3.1 2.3 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KKK15329.1 - 3.8e-07 30.1 4.5 7.4e-06 26.0 0.8 2.5 1 1 1 2 2 2 2 Phospholipid methyltransferase NfeD PF01957.13 KKK15329.1 - 0.017 15.2 0.3 0.63 10.1 0.1 2.7 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding ERG4_ERG24 PF01222.12 KKK15329.1 - 0.026 13.0 0.3 0.039 12.5 0.2 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family RTA1 PF04479.8 KKK15330.1 - 3.9e-46 157.3 1.2 6.4e-46 156.6 0.8 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2975 PF11188.3 KKK15330.1 - 1.2 8.8 7.8 4.6 6.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) MFS_1 PF07690.11 KKK15331.1 - 9.1e-40 136.4 56.0 9.1e-40 136.4 38.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Bys1 PF04681.7 KKK15332.1 - 1.5e-15 57.2 0.8 1.7e-15 57.0 0.6 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Aldo_ket_red PF00248.16 KKK15333.1 - 3.5e-44 150.7 0.0 4.1e-43 147.2 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DUF2697 PF10906.3 KKK15334.1 - 2.4e-05 24.2 0.0 3.2e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2697) Y_phosphatase PF00102.22 KKK15335.1 - 4.8e-52 176.6 0.0 2.4e-51 174.3 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KKK15335.1 - 0.0016 18.5 0.0 0.0061 16.6 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 KKK15335.1 - 0.0074 15.8 0.0 0.021 14.4 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KKK15335.1 - 0.029 14.6 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Mid2 PF04478.7 KKK15336.1 - 2.6e-06 26.9 3.9 2.6e-06 26.9 2.7 3.3 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor DUF4345 PF14248.1 KKK15336.1 - 0.018 14.4 0.4 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Macoilin PF09726.4 KKK15336.1 - 0.27 9.4 20.7 0.36 9.0 14.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 KKK15336.1 - 0.53 7.9 14.6 0.66 7.5 10.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp14 PF04615.8 KKK15336.1 - 1.7 6.7 6.7 1.9 6.5 4.6 1.1 1 0 0 1 1 1 0 Utp14 protein GCOM2 PF15328.1 KKK15336.1 - 3.1 7.4 10.3 4.1 7.0 7.1 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF572 PF04502.8 KKK15336.1 - 4.4 6.4 15.8 5.7 6.0 10.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Suf PF05843.9 KKK15336.1 - 6.6 6.3 6.7 8.3 6.0 4.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) KIAA1328 PF15369.1 KKK15336.1 - 9.7 5.8 13.2 12 5.5 9.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 DNA_ligase_A_C PF04679.10 KKK15337.1 - 0.053 13.9 0.1 5.1 7.5 0.0 3.1 2 1 1 3 3 3 0 ATP dependent DNA ligase C terminal region Pex19 PF04614.7 KKK15338.1 - 9.2e-69 231.8 14.2 1.9e-68 230.7 9.9 1.7 1 1 0 1 1 1 1 Pex19 protein family Ebola_NP PF05505.7 KKK15338.1 - 0.037 12.1 2.1 0.047 11.7 1.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein T2SF PF00482.18 KKK15338.1 - 0.61 9.9 2.6 11 5.9 0.1 3.1 4 1 0 4 4 4 0 Type II secretion system (T2SS), protein F FliE PF02049.13 KKK15338.1 - 1.6 8.7 7.9 0.57 10.2 0.4 3.2 1 1 2 3 3 3 0 Flagellar hook-basal body complex protein FliE WD40 PF00400.27 KKK15339.1 - 8.6e-62 202.9 23.9 9.9e-11 41.1 0.0 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KKK15339.1 - 6.7e-15 54.5 0.7 1.8e-14 53.1 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK15339.1 - 5.2e-12 45.1 1.3 2.8e-11 42.7 0.2 2.4 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 KKK15339.1 - 2.8e-09 35.6 10.9 0.0029 15.7 0.1 5.7 1 1 3 5 5 5 4 Nucleoporin Nup120/160 PRANC PF09372.5 KKK15339.1 - 0.024 14.6 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Nucleoporin_N PF08801.6 KKK15339.1 - 0.047 12.4 0.4 8.6 4.9 0.1 2.7 1 1 1 2 2 2 0 Nup133 N terminal like DUF281 PF03436.8 KKK15340.1 - 0.24 11.5 0.1 0.45 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF281) HAD_2 PF13419.1 KKK15341.1 - 8.9e-33 113.9 0.1 1.1e-32 113.7 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK15341.1 - 4.8e-06 27.1 0.0 6.7e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK15341.1 - 3.3e-05 23.5 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4437 PF14499.1 KKK15341.1 - 0.0069 15.3 0.0 0.014 14.3 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4437) 5_nucleotid PF05761.9 KKK15341.1 - 0.066 11.7 0.1 0.2 10.1 0.1 1.9 1 1 1 2 2 2 0 5' nucleotidase family APG17 PF04108.7 KKK15342.1 - 2.6e-148 494.2 0.0 3e-148 494.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Snapin_Pallidin PF14712.1 KKK15342.1 - 0.073 13.3 1.6 26 5.2 0.0 3.7 4 1 1 5 5 5 0 Snapin/Pallidin Macro_2 PF14519.1 KKK15343.1 - 0.0045 16.1 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Curto_V3 PF07436.6 KKK15343.1 - 0.064 13.3 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Curtovirus V3 protein TB2_DP1_HVA22 PF03134.14 KKK15344.1 - 1.7e-30 104.6 6.9 2.3e-30 104.1 4.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RhodobacterPufX PF11511.3 KKK15344.1 - 3.6 7.0 4.9 2 7.8 0.9 2.3 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF4560 PF15118.1 KKK15344.1 - 7.3 6.4 6.9 1 9.2 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4560) Acid_PPase PF12689.2 KKK15362.1 - 8.2e-70 233.8 0.0 9.6e-70 233.5 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 KKK15362.1 - 0.038 14.2 1.1 0.57 10.3 0.1 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.3 KKK15363.1 - 4.3e-45 153.9 0.0 6.3e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15363.1 - 2.5e-08 33.6 10.8 5.4e-08 32.6 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK15365.1 - 1.4e-25 89.7 39.2 1.4e-25 89.7 27.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK15365.1 - 8.7e-09 34.4 30.3 2.7e-08 32.8 21.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter P5CR_dimer PF14748.1 KKK15365.1 - 0.059 13.3 0.1 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation TRI12 PF06609.8 KKK15365.1 - 0.063 11.4 11.5 0.0044 15.2 3.8 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF2206 PF09971.4 KKK15365.1 - 0.43 9.3 8.1 0.1 11.3 2.9 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2206) Fungal_trans PF04082.13 KKK15366.1 - 4.1e-19 68.4 5.1 6.5e-19 67.8 3.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KKK15366.1 - 3.4e-07 30.2 15.2 0.0001 22.4 4.0 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK15366.1 - 3.4e-05 23.8 13.3 0.004 17.3 3.6 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK15366.1 - 0.004 17.4 19.6 0.035 14.4 4.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.13 KKK15367.1 - 0.0016 18.3 12.2 0.0031 17.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KKK15367.1 - 0.091 12.0 0.0 0.24 10.6 0.0 1.7 1 0 0 1 1 1 0 Histone chaperone domain CHZ RNA_pol_Rpc4 PF05132.9 KKK15368.1 - 4.7e-33 113.9 0.0 4.7e-33 113.9 0.0 4.2 2 2 1 4 4 4 1 RNA polymerase III RPC4 PBP1_TM PF14812.1 KKK15368.1 - 0.021 15.0 10.4 0.021 15.0 7.2 4.7 4 2 1 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 7tm_1 PF00001.16 KKK15369.1 - 0.052 12.6 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Neur_chan_memb PF02932.11 KKK15369.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPRTase PF14681.1 KKK15370.1 - 1.9e-71 239.5 0.0 2.2e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KKK15370.1 - 2.9e-06 27.0 0.0 6.5e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.10 KKK15371.1 - 1.6e-30 105.4 20.5 1.8e-18 66.5 5.7 3.6 3 1 1 4 4 4 3 CrcB-like protein Cyclin_N PF00134.18 KKK15372.1 - 8.1e-44 148.2 0.2 1.6e-43 147.2 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KKK15372.1 - 3.3e-29 101.2 0.2 1.1e-28 99.5 0.1 2.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain Glyco_hydro_92 PF07971.7 KKK15373.1 - 4.6e-171 569.8 0.0 5.9e-171 569.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 4HBT PF03061.17 KKK15374.1 - 2.5e-13 49.9 0.0 4.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Peptidase_M16_C PF05193.16 KKK15374.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 Peptidase M16 inactive domain Aminotran_5 PF00266.14 KKK15375.1 - 4.6e-22 78.2 0.0 2.5e-18 66.0 0.0 3.1 1 1 0 1 1 1 1 Aminotransferase class-V 2OG-FeII_Oxy_4 PF13661.1 KKK15375.1 - 0.044 13.4 0.0 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily RhoGEF PF00621.15 KKK15383.1 - 4.2e-32 111.4 0.8 7e-32 110.7 0.6 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 KKK15383.1 - 3.9e-31 106.9 0.0 1.2e-30 105.4 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin DUF4071 PF13281.1 KKK15383.1 - 0.11 11.2 1.1 1.8 7.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4071) FIVAR PF07554.8 KKK15383.1 - 0.16 12.2 0.7 0.88 9.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain DUF4404 PF14357.1 KKK15383.1 - 0.18 12.2 4.3 0.87 10.0 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) WD40 PF00400.27 KKK15384.1 - 3.3e-44 147.2 9.4 5.5e-08 32.4 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KKK15384.1 - 2.3e-13 49.6 0.4 5.6e-13 48.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK15384.1 - 5e-08 32.4 0.3 1.1e-07 31.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KKK15384.1 - 0.00044 18.5 2.1 0.33 9.0 0.0 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KKK15384.1 - 0.02 14.6 0.2 38 4.1 0.0 4.8 5 2 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region DUF605 PF04652.11 KKK15384.1 - 0.19 11.0 17.7 0.14 11.4 7.8 2.1 2 0 0 2 2 2 0 Vta1 like Tmemb_14 PF03647.8 KKK15385.1 - 5.1e-23 81.2 9.6 6.9e-23 80.8 6.6 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C MFS_1 PF07690.11 KKK15386.1 - 2.2e-29 102.2 15.7 2.2e-29 102.2 10.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK15386.1 - 4.9e-08 31.9 6.7 4.9e-08 31.9 4.7 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter TFR_dimer PF04253.10 KKK15387.1 - 3e-19 68.8 0.0 5.1e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KKK15387.1 - 9.2e-15 54.8 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KKK15387.1 - 2.8e-08 33.3 0.0 8.3e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 PA domain CMD PF02627.15 KKK15387.1 - 1e-05 25.2 0.0 3.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Nicastrin PF05450.10 KKK15387.1 - 0.0059 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Nicastrin DUF1356 PF07092.7 KKK15387.1 - 0.2 10.8 0.4 0.33 10.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) DUF2413 PF10310.4 KKK15388.1 - 2.6e-152 507.7 0.0 3e-152 507.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 KKK15388.1 - 0.012 15.5 3.1 0.2 11.7 0.9 2.5 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain SurE PF01975.12 KKK15389.1 - 2.1e-43 147.9 0.0 2.8e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_28 PF03033.15 KKK15389.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Zn_clus PF00172.13 KKK15390.1 - 0.0015 18.4 10.2 0.003 17.4 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KKK15391.1 - 0.00097 19.3 1.2 0.06 13.7 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK15391.1 - 0.0013 18.9 3.0 0.04 14.2 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type HDV_ag PF01517.13 KKK15391.1 - 0.0019 17.9 0.1 0.004 16.8 0.1 1.5 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen zf-Di19 PF05605.7 KKK15391.1 - 0.11 12.6 1.2 4.6 7.4 0.8 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.10 KKK15391.1 - 5.9 6.4 5.1 10 5.6 0.5 2.4 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Methyltransf_18 PF12847.2 KKK15393.1 - 2.6e-18 66.6 0.0 3.8e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK15393.1 - 2.5e-12 46.6 0.0 1.3e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK15393.1 - 3.7e-07 30.0 0.0 9.8e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK15393.1 - 3.1e-06 27.2 0.0 9e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK15393.1 - 7.6e-05 23.1 0.1 0.00042 20.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK15393.1 - 0.0005 20.3 0.0 0.0016 18.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KKK15393.1 - 0.00087 18.7 0.1 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 KKK15393.1 - 0.0045 17.4 0.1 0.014 15.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KKK15393.1 - 0.019 14.9 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 KKK15393.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 KKK15393.1 - 0.1 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KKK15393.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S9 PF00380.14 KKK15394.1 - 3.3e-37 127.4 0.2 5.2e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 KKK15395.1 - 1.8e-43 146.6 0.1 3.3e-43 145.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KKK15395.1 - 8.5e-13 48.1 0.0 1.9e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK15395.1 - 7.9e-10 38.4 0.1 7.2e-09 35.4 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK15395.1 - 7.9e-09 35.5 0.0 2.7e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KKK15395.1 - 6.4e-06 26.5 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KKK15395.1 - 0.00083 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK15395.1 - 0.077 13.0 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PP2C PF00481.16 KKK15396.1 - 1e-51 175.8 0.0 1.8e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KKK15396.1 - 1.2e-43 146.0 51.1 8e-08 31.7 0.2 11.9 7 3 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK15396.1 - 5.7e-36 122.0 52.7 4.4e-07 29.5 0.1 10.2 7 3 5 12 12 12 10 Leucine rich repeat Guanylate_cyc PF00211.15 KKK15396.1 - 8.5e-29 100.2 0.0 1.6e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KKK15396.1 - 1.7e-14 51.6 60.4 0.087 12.9 0.1 17.2 16 3 1 17 17 17 8 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 KKK15396.1 - 8e-11 41.1 0.1 2.5e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 KKK15396.1 - 2.7e-06 26.6 45.6 0.23 11.8 0.2 15.0 18 0 0 18 18 15 2 Leucine rich repeat RA PF00788.18 KKK15396.1 - 6e-06 26.6 0.0 3.8e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.1 KKK15396.1 - 0.00041 19.9 10.1 0.84 9.1 0.0 4.6 2 1 3 5 5 5 2 Leucine-rich repeat PP2C_2 PF13672.1 KKK15396.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C LRR_5 PF13306.1 KKK15396.1 - 0.013 15.2 5.9 2.6 7.7 0.0 4.8 5 1 0 5 5 5 0 Leucine rich repeats (6 copies) Zn_clus PF00172.13 KKK15397.1 - 3.1e-07 30.1 9.3 4.5e-07 29.6 6.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMC_Nse1 PF07574.8 KKK15397.1 - 0.049 13.2 0.1 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Dickkopf_N PF04706.7 KKK15397.1 - 8 6.7 12.0 27 5.0 8.2 1.8 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region MSC PF09402.5 KKK15398.1 - 2.2e-97 325.8 0.0 2.9e-97 325.3 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KKK15398.1 - 6.2e-17 60.8 0.1 1.1e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 HeH/LEM domain APH PF01636.18 KKK15399.1 - 0.00011 22.0 0.1 0.00035 20.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK15399.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase MOZ_SAS PF01853.13 KKK15400.1 - 2.9e-55 186.4 0.0 2.6e-53 180.1 0.0 2.1 1 1 1 2 2 2 2 MOZ/SAS family Cpn60_TCP1 PF00118.19 KKK15401.1 - 1.2e-147 492.5 0.1 1.3e-147 492.3 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2 PF00152.15 KKK15402.1 - 5.4e-56 189.7 0.0 9.8e-56 188.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) RRM_1 PF00076.17 KKK15402.1 - 1.1e-11 44.1 0.0 2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK15402.1 - 2.4e-09 37.0 0.0 1.2e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) tRNA_anti-codon PF01336.20 KKK15402.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RRM_5 PF13893.1 KKK15402.1 - 0.13 12.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 PF10446.4 KKK15403.1 - 0.0013 17.5 5.3 0.0015 17.3 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop PF01798.13 KKK15404.1 - 3.7e-60 201.5 0.1 3.7e-60 201.5 0.0 1.8 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KKK15404.1 - 4e-25 87.3 0.4 8.8e-25 86.2 0.3 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KKK15404.1 - 8.5e-22 77.0 0.1 8.5e-22 77.0 0.0 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Abi_2 PF07751.6 KKK15404.1 - 6.4 6.9 8.1 48 4.0 4.7 2.4 2 0 0 2 2 2 0 Abi-like protein G0-G1_switch_2 PF15103.1 KKK15404.1 - 9.1 6.5 8.0 72 3.6 0.0 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF1744 PF08490.7 KKK15405.1 - 2e-153 510.6 0.0 2.9e-153 510.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KKK15405.1 - 1.9e-71 240.6 0.6 1.4e-70 237.7 0.3 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KKK15405.1 - 2.2e-23 82.8 0.1 5.1e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KKK15405.1 - 1.7e-09 37.5 0.0 4.2e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KKK15405.1 - 2.2e-05 24.3 0.1 8.8e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.3 KKK15406.1 - 2.6e-39 133.5 0.8 3.6e-39 133.0 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) PP1c_bdg PF10488.4 KKK15406.1 - 0.42 9.7 3.7 0.11 11.6 0.6 1.4 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region Utp8 PF10395.4 KKK15410.1 - 0.028 12.7 0.1 1.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Utp8 family Ribosomal_S20p PF01649.13 KKK15410.1 - 0.062 13.6 0.1 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S20 PX PF00787.19 KKK15411.1 - 1.8e-17 63.1 0.4 4.5e-17 61.8 0.3 1.7 1 0 0 1 1 1 1 PX domain AAA PF00004.24 KKK15411.1 - 5.4e-09 36.3 0.0 2.6e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK15411.1 - 3.1e-06 27.3 0.1 1.9e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK15411.1 - 9.9e-06 25.6 0.9 0.00043 20.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 KKK15411.1 - 0.00047 18.9 0.2 0.0028 16.4 0.0 2.3 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KKK15411.1 - 0.006 17.4 0.1 0.028 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KKK15411.1 - 0.013 14.5 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KKK15411.1 - 0.018 14.7 0.0 0.06 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KKK15411.1 - 0.029 13.0 0.0 0.054 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 KKK15411.1 - 0.11 12.3 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-C2H2_4 PF13894.1 KKK15412.1 - 2e-10 40.2 12.8 0.006 16.8 0.4 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK15412.1 - 4.1e-09 36.2 14.8 0.00014 22.0 0.5 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK15412.1 - 6.6e-08 32.4 0.7 6.6e-08 32.4 0.5 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KKK15412.1 - 2.7 8.0 14.1 1.4 8.8 0.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger LysM PF01476.15 KKK15413.1 - 3.4e-05 23.6 1.3 6.1e-05 22.8 0.0 2.1 3 0 0 3 3 3 1 LysM domain Fungal_trans PF04082.13 KKK15414.1 - 1e-25 90.1 2.2 1.8e-25 89.3 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15414.1 - 2.2e-08 33.8 12.1 4.6e-08 32.8 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tautomerase_3 PF14832.1 KKK15415.1 - 3.8e-50 169.4 0.1 4.3e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Epimerase PF01370.16 KKK15416.1 - 1.1e-15 57.7 0.0 3.3e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK15416.1 - 4.7e-12 45.1 0.0 1.8e-11 43.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KKK15416.1 - 5.5e-12 46.0 0.0 2.5e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KKK15416.1 - 6.8e-07 28.4 0.0 1.2e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KKK15416.1 - 1.7e-05 24.8 0.0 7.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KKK15416.1 - 6e-05 22.0 0.0 0.00012 21.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KKK15416.1 - 0.0011 18.3 0.0 0.0078 15.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 KKK15416.1 - 0.026 14.1 0.1 0.32 10.6 0.0 2.2 1 1 0 1 1 1 0 KR domain ECH PF00378.15 KKK15417.1 - 9.6e-44 149.3 0.1 1.6e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HMGL-like PF00682.14 KKK15417.1 - 1.5e-40 139.3 0.0 2.3e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 HMGL-like AMP-binding PF00501.23 KKK15418.1 - 3.4e-78 262.8 0.0 4.5e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK15418.1 - 1.3e-12 48.4 0.0 2.8e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GATase PF00117.23 KKK15418.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Zn_clus PF00172.13 KKK15419.1 - 3.1e-08 33.3 12.1 5.1e-08 32.6 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK15419.1 - 0.0013 17.3 0.1 0.28 9.7 0.0 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.19 KKK15420.1 - 3.2e-29 101.9 2.4 4.7e-29 101.4 1.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KKK15420.1 - 1.4e-19 70.7 0.1 6.8e-19 68.5 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KKK15420.1 - 2e-19 68.8 1.0 3.5e-19 68.0 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KKK15420.1 - 0.0003 21.0 1.0 0.00043 20.5 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ATP-sulfurylase PF01747.12 KKK15420.1 - 0.12 11.6 0.1 0.56 9.4 0.0 2.0 2 0 0 2 2 2 0 ATP-sulfurylase Carboxyl_trans PF01039.17 KKK15421.1 - 2e-112 376.0 0.0 2.6e-112 375.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KKK15422.1 - 2.1e-70 236.3 0.0 3.5e-70 235.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KKK15422.1 - 7.5e-31 106.2 0.0 2.3e-30 104.6 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KKK15422.1 - 1.8e-29 102.0 0.6 5.5e-18 65.0 0.0 2.9 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KKK15422.1 - 8e-16 58.3 0.0 1.4e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KKK15422.1 - 1.9e-12 46.5 2.3 4e-12 45.6 1.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KKK15422.1 - 7.2e-11 41.3 0.0 1.9e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK15422.1 - 2.6e-09 36.7 0.0 5.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KKK15422.1 - 3.5e-09 36.2 0.0 7.6e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KKK15422.1 - 5e-05 22.8 0.0 0.00017 21.1 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KKK15422.1 - 5.7e-05 23.0 0.0 9.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KKK15422.1 - 0.031 13.9 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like GCV_H PF01597.14 KKK15422.1 - 0.071 12.8 0.0 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 Glycine cleavage H-protein ATPgrasp_YheCD PF14398.1 KKK15422.1 - 0.12 11.1 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 YheC/D like ATP-grasp DUF3182 PF11379.3 KKK15422.1 - 0.16 10.6 0.0 0.31 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) HlyD_3 PF13437.1 KKK15422.1 - 0.18 12.1 0.0 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 HlyD family secretion protein PHD PF00628.24 KKK15423.1 - 1.3e-08 34.4 9.0 2.5e-08 33.4 6.2 1.5 1 0 0 1 1 1 1 PHD-finger DivIC PF04977.10 KKK15423.1 - 0.05 13.0 0.3 0.075 12.5 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator zf-HC5HC2H PF13771.1 KKK15423.1 - 0.21 11.7 3.9 0.42 10.8 2.7 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 KKK15423.1 - 3.3 7.5 10.7 1.6 8.5 4.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KKK15423.1 - 3.3 7.0 8.0 0.29 10.4 1.6 2.1 2 0 0 2 2 2 0 PHD-finger Peptidase_S10 PF00450.17 KKK15424.1 - 1.2e-92 311.2 0.1 1.6e-92 310.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase YXWGXW PF12779.2 KKK15424.1 - 0.21 11.5 0.7 0.46 10.4 0.5 1.6 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) Glyco_hydro_92 PF07971.7 KKK15425.1 - 5.2e-174 579.5 0.0 6.9e-174 579.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 AA_permease_2 PF13520.1 KKK15426.1 - 3.3e-55 187.3 40.8 4e-55 187.0 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK15426.1 - 9e-21 73.7 28.6 9e-21 73.7 19.8 2.1 2 0 0 2 2 2 1 Amino acid permease Glyco_hydro_76 PF03663.9 KKK15427.1 - 3.5e-124 414.9 23.8 2e-122 409.1 16.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Kdo PF06293.9 KKK15428.1 - 1.8e-05 23.8 1.6 1.9e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KKK15428.1 - 0.00094 18.3 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KKK15428.1 - 0.0021 17.8 0.1 0.0021 17.8 0.1 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK15428.1 - 0.043 13.3 0.1 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KKK15428.1 - 0.059 12.7 0.0 0.059 12.7 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Synaptobrevin PF00957.16 KKK15428.1 - 0.15 11.6 1.7 0.32 10.6 1.2 1.5 1 0 0 1 1 1 0 Synaptobrevin DUF3492 PF11997.3 KKK15428.1 - 1.6 8.2 4.0 2.7 7.4 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) EMP24_GP25L PF01105.19 KKK15428.1 - 4.6 6.9 5.7 9.1 5.9 4.0 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD HSP70 PF00012.15 KKK15428.1 - 5.2 4.8 12.2 7.4 4.3 8.4 1.1 1 0 0 1 1 1 0 Hsp70 protein Atg14 PF10186.4 KKK15428.1 - 6.5 5.6 18.9 12 4.7 13.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HAUS6_N PF14661.1 KKK15428.1 - 10 5.4 14.2 20 4.4 9.8 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus adh_short_C2 PF13561.1 KKK15447.1 - 1.1e-17 64.6 0.0 1.5e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK15447.1 - 2.2e-16 60.2 0.3 4e-16 59.3 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK15447.1 - 0.00092 18.9 0.1 0.0071 16.0 0.1 2.2 1 1 0 1 1 1 1 KR domain DUF3535 PF12054.3 KKK15448.1 - 7.4e-151 502.7 0.0 2.6e-150 500.9 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KKK15448.1 - 7.6e-72 241.6 0.0 1.1e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KKK15448.1 - 1.1e-15 56.1 16.9 0.2 11.8 0.0 10.8 11 0 0 11 11 11 6 HEAT repeat Helicase_C PF00271.26 KKK15448.1 - 2.3e-14 53.0 0.0 6e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KKK15448.1 - 4.6e-07 30.1 0.1 0.078 13.3 0.0 4.0 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KKK15448.1 - 2.4e-06 27.7 13.7 0.0045 17.2 0.1 7.1 6 2 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 KKK15448.1 - 0.0021 18.5 19.6 2.1 8.9 0.0 8.7 9 0 0 9 9 9 1 HEAT-like repeat Cnd1 PF12717.2 KKK15448.1 - 0.015 15.1 0.1 5.5 6.8 0.0 4.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KKK15448.1 - 0.03 13.6 0.1 5.7 6.2 0.0 3.7 2 1 2 4 4 4 0 CLASP N terminal DUF533 PF04391.7 KKK15449.1 - 0.081 12.2 3.1 0.61 9.4 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF533) Kelch_3 PF13415.1 KKK15450.1 - 6.6e-06 26.1 11.0 0.0013 18.7 0.2 5.4 4 2 1 5 5 5 2 Galactose oxidase, central domain TMEM154 PF15102.1 KKK15450.1 - 0.00022 20.9 0.0 0.00064 19.4 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family Kelch_5 PF13854.1 KKK15450.1 - 0.00023 21.0 2.3 1.2 9.1 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 KKK15450.1 - 0.0061 16.6 6.9 3 8.1 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Rifin_STEVOR PF02009.11 KKK15450.1 - 0.0082 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family Gly-zipper_Omp PF13488.1 KKK15450.1 - 0.085 12.5 1.8 0.095 12.3 0.1 2.0 2 0 0 2 2 2 0 Glycine zipper SKG6 PF08693.5 KKK15450.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2407_C PF13373.1 KKK15450.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF974 PF06159.8 KKK15451.1 - 2.5e-78 262.9 0.0 3e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) BNR_2 PF13088.1 KKK15462.1 - 1.5e-05 24.3 0.0 0.016 14.5 0.0 2.2 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KKK15462.1 - 0.00011 21.4 5.9 0.016 14.9 0.1 3.5 3 0 0 3 3 3 2 BNR/Asp-box repeat Bys1 PF04681.7 KKK15463.1 - 2.5e-08 33.7 0.0 2.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Arylsulfotran_2 PF14269.1 KKK15464.1 - 3e-110 368.0 5.4 3.6e-110 367.7 3.7 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KKK15464.1 - 0.00014 20.5 4.7 0.00053 18.6 3.2 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Fe-ADH PF00465.14 KKK15465.1 - 5.1e-97 324.7 0.0 5.8e-97 324.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KKK15465.1 - 1.5e-16 60.4 0.0 2.8e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KKK15465.1 - 0.00019 20.9 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Toprim_3 PF13362.1 KKK15465.1 - 0.062 13.5 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Toprim domain Pkinase PF00069.20 KKK15466.1 - 1.3e-66 224.4 0.0 1.5e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15466.1 - 2.1e-32 112.1 0.0 2.6e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK15466.1 - 3.5e-07 29.4 0.0 4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK15466.1 - 0.0055 15.7 0.1 0.0098 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK15466.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK15466.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_43 PF04616.9 KKK15467.1 - 7.8e-27 94.0 8.7 6.7e-20 71.3 0.6 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Ank_2 PF12796.2 KKK15468.1 - 1.3e-107 352.3 22.0 1.6e-22 79.6 0.2 8.5 3 2 6 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KKK15468.1 - 7.2e-86 278.0 12.4 1e-10 40.8 0.0 15.2 14 1 1 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 KKK15468.1 - 8.3e-79 258.7 9.5 2.1e-12 47.2 0.0 10.9 7 2 4 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK15468.1 - 5.1e-78 249.1 4.9 1.2e-06 28.1 0.0 16.4 17 0 0 17 17 17 13 Ankyrin repeat Ank_5 PF13857.1 KKK15468.1 - 1.6e-67 222.0 21.2 1.5e-08 34.6 0.0 14.4 4 2 11 15 15 15 13 Ankyrin repeats (many copies) CorA PF01544.13 KKK15468.1 - 0.0014 17.7 1.8 0.0014 17.7 1.3 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF3447 PF11929.3 KKK15468.1 - 0.17 11.6 0.0 14 5.5 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) DcpS PF05652.7 KKK15470.1 - 1.1e-31 109.5 0.0 1.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 KKK15470.1 - 6e-30 103.8 0.0 9.4e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MT-A70 PF05063.9 KKK15471.1 - 2e-23 82.8 0.2 4e-23 81.8 0.2 1.6 1 0 0 1 1 1 1 MT-A70 PUF PF00806.14 KKK15472.1 - 1.2e-27 93.8 0.0 1.4e-05 24.3 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KKK15472.1 - 5.4e-11 41.9 0.0 1.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK15472.1 - 5.5e-08 32.5 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK15472.1 - 4.3e-05 23.4 0.0 9.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.8 KKK15473.1 - 9.2e-63 212.0 23.4 9.2e-63 212.0 16.2 3.9 3 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 KKK15473.1 - 2e-12 46.4 0.5 1.3e-11 43.8 0.1 2.2 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Peptidase_C12 PF01088.16 KKK15474.1 - 2.4e-55 187.0 0.0 2.9e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ETC_C1_NDUFA4 PF04800.7 KKK15475.1 - 1.8e-37 127.2 0.7 2.5e-37 126.7 0.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region MOZ_SAS PF01853.13 KKK15476.1 - 3.4e-84 280.7 0.1 5.2e-84 280.1 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Myb_Cef PF11831.3 KKK15476.1 - 9.9e-66 221.2 1.0 9.9e-66 221.2 0.7 5.2 5 1 0 5 5 5 2 pre-mRNA splicing factor component Tudor-knot PF11717.3 KKK15476.1 - 4.4e-22 77.5 0.0 1.3e-21 76.0 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Myb_DNA-binding PF00249.26 KKK15476.1 - 2.2e-18 66.0 2.5 1.3e-08 34.7 0.3 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK15476.1 - 1.2e-17 63.7 3.5 1.8e-11 43.9 0.4 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2314 PF10077.4 KKK15476.1 - 0.066 13.2 1.1 0.56 10.2 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2314) F1F0-ATPsyn_F PF10791.4 KKK15477.1 - 2.4e-34 117.4 0.3 6.9e-34 115.9 0.2 1.9 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi RNase_H2_suC PF08615.6 KKK15478.1 - 4e-30 104.4 0.0 5e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nop53 PF07767.6 KKK15479.1 - 8.3e-105 350.9 37.2 5.3e-91 305.4 18.1 4.0 3 1 1 4 4 4 2 Nop53 (60S ribosomal biogenesis) RNase_T PF00929.19 KKK15479.1 - 2.1e-26 93.1 0.0 2.3e-25 89.7 0.0 2.4 2 0 0 2 2 2 1 Exonuclease GCV_T PF01571.16 KKK15480.1 - 2.4e-15 56.5 0.0 4.6e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KKK15480.1 - 0.00098 19.1 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DCP2 PF05026.8 KKK15481.1 - 4e-36 122.7 1.1 6.7e-36 122.0 0.8 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KKK15481.1 - 7.3e-16 58.0 0.0 1.5e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 KKK15482.1 - 1.1e-33 115.2 0.4 1.4e-33 114.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2392 PF10288.4 KKK15483.1 - 3.3e-27 94.9 0.0 5.7e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DSPc PF00782.15 KKK15484.1 - 4.6e-23 81.2 0.0 6.2e-22 77.6 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Sugar_tr PF00083.19 KKK15487.1 - 1e-33 116.6 11.5 1.1e-33 116.4 8.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Flavi_NS4A PF01350.12 KKK15487.1 - 0.92 9.0 4.4 0.94 9.0 0.6 2.1 1 1 1 2 2 2 0 Flavivirus non-structural protein NS4A Bax1-I PF01027.15 KKK15487.1 - 1 8.9 15.8 4.3 6.8 11.2 1.9 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Tic20 PF09685.5 KKK15487.1 - 2.8 7.9 10.7 21 5.1 7.4 2.1 1 1 0 1 1 1 0 Tic20-like protein Pkinase PF00069.20 KKK15492.1 - 1.1e-19 70.6 0.0 1.4e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15492.1 - 1.5e-16 60.2 0.0 2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK15492.1 - 0.00028 19.9 0.0 0.00066 18.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK15492.1 - 0.0016 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC5HC2H_2 PF13832.1 KKK15500.1 - 4.1e-22 78.2 0.4 4.1e-22 78.2 0.3 4.1 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KKK15500.1 - 4.7e-22 77.9 2.3 4.7e-22 77.9 1.6 4.8 4 0 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 KKK15500.1 - 3.8e-16 58.9 0.1 1e-15 57.5 0.1 1.7 2 0 0 2 2 2 1 BAH domain PHD PF00628.24 KKK15500.1 - 1e-10 41.1 19.9 7.5e-07 28.7 3.8 5.6 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.1 KKK15500.1 - 1e-09 37.5 4.5 1e-09 37.5 3.1 5.1 5 0 0 5 5 5 1 PHD-finger Myb_DNA-binding PF00249.26 KKK15500.1 - 6.1e-05 22.9 0.1 0.00017 21.5 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_1 PF00130.17 KKK15500.1 - 0.0044 16.7 1.9 0.0044 16.7 1.3 5.9 7 1 1 8 8 8 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KKK15500.1 - 0.078 12.7 32.1 0.091 12.5 3.7 4.6 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 DUF998 PF06197.8 KKK15502.1 - 0.0019 17.5 4.1 0.037 13.3 1.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF998) DUF202 PF02656.10 KKK15502.1 - 0.0026 17.9 6.9 0.02 15.1 4.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF202) RseC_MucC PF04246.7 KKK15502.1 - 0.15 11.5 0.9 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC 6PF2K PF01591.13 KKK15503.1 - 5.1e-68 228.4 0.0 4.5e-48 163.2 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KKK15503.1 - 3.8e-28 98.5 0.0 9.6e-28 97.2 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KKK15503.1 - 2e-06 27.7 0.0 0.0093 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK15503.1 - 0.0018 19.0 0.0 0.006 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KKK15503.1 - 0.045 12.9 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KKK15503.1 - 0.16 11.0 0.1 2.1 7.3 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin DSBA PF01323.15 KKK15504.1 - 3.3e-31 108.3 0.0 8e-15 54.8 0.0 2.0 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Frag1 PF10277.4 KKK15505.1 - 1.3e-11 44.3 0.0 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Trypan_PARP PF05887.6 KKK15505.1 - 9.7e-05 22.2 7.0 0.00018 21.3 4.9 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) VTC PF09359.5 KKK15506.1 - 4.3e-90 301.5 0.0 7.5e-90 300.7 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KKK15506.1 - 1.3e-17 64.5 13.9 2.9e-12 46.9 0.5 4.2 2 2 1 3 3 3 2 SPX domain DUF202 PF02656.10 KKK15506.1 - 2e-09 37.5 5.3 5e-09 36.2 2.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3815 PF12821.2 KKK15506.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) NUDIX PF00293.23 KKK15507.1 - 7.5e-13 48.2 0.0 1.6e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.18 KKK15507.1 - 0.00099 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR_2 PF13233.1 KKK15508.1 - 0.31 11.5 3.1 0.64 10.5 2.1 1.5 1 0 0 1 1 1 0 Complex1_LYR-like TBPIP PF07106.8 KKK15508.1 - 0.64 9.5 10.3 2.1 7.8 5.2 2.5 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SNF2_N PF00176.18 KKK15510.1 - 2.3e-63 213.7 0.2 4.3e-63 212.8 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK15510.1 - 1.9e-12 46.8 0.0 6.8e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KKK15510.1 - 2.7e-05 23.7 10.5 2.7e-05 23.7 7.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK15510.1 - 0.0029 17.4 11.7 0.0029 17.4 8.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KKK15510.1 - 0.0056 16.6 11.6 0.0056 16.6 8.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LRR_6 PF13516.1 KKK15511.1 - 0.00021 21.0 5.7 9.8 6.5 0.1 6.8 8 0 0 8 8 8 2 Leucine Rich repeat FYVE PF01363.16 KKK15511.1 - 0.1 12.5 0.2 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 FYVE zinc finger CDC45 PF02724.9 KKK15511.1 - 4.7 5.1 6.5 25 2.7 4.8 1.8 2 0 0 2 2 2 0 CDC45-like protein Trypan_PARP PF05887.6 KKK15511.1 - 6.6 6.5 11.9 1.4 8.7 1.5 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) EF-hand_4 PF12763.2 KKK15512.1 - 4.6e-27 93.7 0.0 7.5e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 KKK15512.1 - 6.2e-11 42.2 120.5 5e-05 23.2 19.0 6.7 4 1 0 4 4 4 3 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 KKK15512.1 - 5.1e-05 23.3 0.7 0.0045 17.0 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KKK15512.1 - 0.06 12.6 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 EF hand RNA_pol_L_2 PF13656.1 KKK15514.1 - 8.5e-23 79.5 0.0 1.3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KKK15514.1 - 9.1e-13 47.1 0.0 2.3e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain IF4E PF01652.13 KKK15515.1 - 3.6e-52 176.2 0.1 5.2e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Zip PF02535.17 KKK15515.1 - 0.0066 15.4 0.5 0.0066 15.4 0.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.9 KKK15515.1 - 1.2 8.4 9.6 1.7 8.0 6.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_C48 PF02902.14 KKK15516.1 - 2.3e-31 109.1 0.0 1.6e-30 106.3 0.0 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AIG2 PF06094.7 KKK15517.1 - 9e-05 22.9 0.2 0.00032 21.1 0.1 1.8 1 1 0 1 1 1 1 AIG2-like family DEP PF00610.16 KKK15520.1 - 6.2e-31 105.9 0.8 1.2e-30 105.0 0.6 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Fungal_trans PF04082.13 KKK15521.1 - 5.4e-13 48.4 0.3 8.4e-13 47.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3608 PF12257.3 KKK15522.1 - 6.4e-73 245.0 0.0 1e-72 244.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) Fungal_trans PF04082.13 KKK15523.1 - 1.9e-21 76.1 0.2 4.2e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15523.1 - 5.5e-09 35.7 12.1 9.6e-09 35.0 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspB PF06667.7 KKK15523.1 - 0.047 13.6 1.5 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Phage shock protein B SelB-wing_1 PF09105.5 KKK15538.1 - 0.086 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Vezatin PF12632.2 KKK15551.1 - 5.4e-56 189.4 0.0 1.2e-55 188.2 0.0 1.6 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.13 KKK15551.1 - 1.1e-52 176.8 2.5 2.2e-52 175.8 1.8 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KKK15551.1 - 4e-51 172.2 0.0 7.7e-51 171.3 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KKK15551.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KKK15551.1 - 0.011 14.6 0.1 0.074 11.9 0.0 2.0 2 0 0 2 2 2 0 Hus1-like protein Glyco_hydro_38 PF01074.17 KKK15564.1 - 6.1e-92 307.7 1.0 6.1e-92 307.7 0.7 2.1 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KKK15564.1 - 2.2e-72 244.3 0.0 4.2e-72 243.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KKK15564.1 - 9.2e-26 89.8 0.0 1.8e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain PHD_3 PF13922.1 KKK15565.1 - 0.37 11.0 3.3 0.88 9.8 2.3 1.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Activator_LAG-3 PF11498.3 KKK15565.1 - 3.7 6.1 20.6 5.5 5.6 11.4 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 LETM1 PF07766.8 KKK15566.1 - 6.8e-105 349.9 0.1 6.8e-105 349.9 0.1 1.4 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 KKK15566.1 - 9.1e-06 25.0 0.0 0.0033 16.8 0.0 3.3 3 0 0 3 3 3 2 SAP domain DUF2838 PF10998.3 KKK15567.1 - 5.3e-44 148.6 10.9 5.3e-44 148.6 7.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Tropomyosin_1 PF12718.2 KKK15567.1 - 0.01 15.6 1.1 0.018 14.8 0.8 1.3 1 0 0 1 1 1 0 Tropomyosin like Atg14 PF10186.4 KKK15567.1 - 0.021 13.7 2.5 0.035 13.0 1.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 KKK15567.1 - 0.081 12.0 2.6 0.14 11.2 1.8 1.3 1 0 0 1 1 1 0 Tropomyosin Val_tRNA-synt_C PF10458.4 KKK15567.1 - 0.58 10.2 6.9 9.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF2841 PF11001.3 KKK15568.1 - 1.5e-46 157.3 0.1 2.5e-46 156.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) AP_endonuc_2 PF01261.19 KKK15569.1 - 1.8e-25 89.4 0.5 2.6e-25 88.9 0.3 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.19 KKK15570.1 - 9.6e-135 449.6 23.3 1.1e-134 449.4 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK15570.1 - 3e-29 101.8 58.6 3.6e-26 91.7 23.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Choline_kinase PF01633.15 KKK15571.1 - 5.2e-46 156.8 0.0 1.1e-44 152.4 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KKK15571.1 - 1.5e-11 44.4 0.3 4.3e-11 42.9 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KKK15571.1 - 0.072 12.2 0.0 0.43 9.6 0.0 2.0 1 1 0 1 1 1 0 Ecdysteroid kinase ETF_QO PF05187.8 KKK15575.1 - 4.4e-45 152.1 0.0 7.5e-45 151.4 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase RRM_1 PF00076.17 KKK15575.1 - 8.3e-18 63.8 0.0 9.7e-08 31.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK15575.1 - 1e-12 47.7 0.0 4.4e-06 26.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK15575.1 - 7.2e-11 41.9 0.0 0.00016 21.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DAO PF01266.19 KKK15575.1 - 8e-09 34.8 0.1 0.00056 18.9 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK15575.1 - 1.5e-07 30.5 0.3 0.0031 16.4 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KKK15575.1 - 2.2e-07 30.7 0.0 8.9e-07 28.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KKK15575.1 - 6e-05 22.2 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK15575.1 - 0.00014 21.8 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK15575.1 - 0.00032 19.8 0.0 0.015 14.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KKK15575.1 - 0.00032 19.3 0.4 0.00053 18.5 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KKK15575.1 - 0.00076 18.6 0.0 0.0016 17.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KKK15575.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK15575.1 - 0.003 17.3 0.0 0.0072 16.1 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KKK15575.1 - 0.0073 16.6 0.1 8.5 6.8 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK15575.1 - 0.033 13.1 0.3 0.049 12.5 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KKK15575.1 - 0.068 11.7 0.0 0.22 10.1 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 KKK15575.1 - 0.19 10.5 0.4 0.29 9.9 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AICARFT_IMPCHas PF01808.13 KKK15576.1 - 1.6e-110 369.1 0.0 2.2e-110 368.6 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KKK15576.1 - 3.7e-25 87.6 0.0 7.5e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Clathrin PF00637.15 KKK15577.1 - 1.8e-202 663.0 34.5 2.4e-33 114.7 1.9 7.7 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KKK15577.1 - 8e-35 116.7 1.5 1.5e-06 28.1 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 KKK15577.1 - 5.9e-31 106.1 0.3 5.9e-31 106.1 0.2 2.6 3 0 0 3 3 3 1 Clathrin-H-link Coatomer_WDAD PF04053.9 KKK15577.1 - 0.0012 17.7 4.1 0.14 10.9 0.2 3.6 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.1 KKK15577.1 - 0.0044 16.7 4.0 52 4.0 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Vps39_1 PF10366.4 KKK15577.1 - 0.032 14.2 7.7 3.5 7.6 0.0 5.3 5 1 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.1 KKK15577.1 - 0.053 14.1 13.4 4.7 8.1 0.1 8.2 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_12 PF13424.1 KKK15577.1 - 0.11 12.4 7.0 4.5 7.2 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK15577.1 - 1.6 9.1 10.5 30 5.0 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat DnaJ PF00226.26 KKK15578.1 - 7.2e-14 51.2 0.0 1.2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Gemini_mov PF01708.11 KKK15578.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein Mus7 PF09462.5 KKK15579.1 - 3.9e-223 742.7 0.0 5.9e-223 742.1 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family PAPA-1 PF04795.7 KKK15580.1 - 5.2e-30 103.9 5.5 5.2e-30 103.9 3.8 2.5 3 0 0 3 3 3 1 PAPA-1-like conserved region Pex14_N PF04695.8 KKK15581.1 - 2.7e-32 111.6 0.0 2.7e-32 111.6 0.0 2.7 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region BNR PF02012.15 KKK15582.1 - 0.043 13.6 0.1 0.38 10.7 0.1 2.8 1 0 0 1 1 1 0 BNR/Asp-box repeat Aldolase_II PF00596.16 KKK15583.1 - 3.3e-06 26.8 0.0 4.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF4050 PF13259.1 KKK15584.1 - 4.7e-45 152.4 0.1 7.3e-45 151.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) AAA PF00004.24 KKK15585.1 - 3.3e-41 140.5 0.0 1.2e-37 129.0 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK15585.1 - 3.5e-05 23.7 0.0 0.0049 16.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK15585.1 - 3.8e-05 23.7 4.0 0.0048 16.8 0.0 4.3 3 1 2 5 5 5 1 AAA ATPase domain RuvB_N PF05496.7 KKK15585.1 - 5.4e-05 22.3 0.0 0.00016 20.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KKK15585.1 - 0.0001 22.4 0.7 0.0029 17.7 0.1 2.9 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 KKK15585.1 - 0.00027 19.7 0.0 0.00062 18.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KKK15585.1 - 0.00066 20.4 0.1 0.0029 18.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK15585.1 - 0.00086 19.0 0.0 0.0024 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KKK15585.1 - 0.0011 18.6 0.4 0.0038 16.9 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KKK15585.1 - 0.0024 17.8 0.1 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KKK15585.1 - 0.0046 16.3 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KKK15585.1 - 0.0055 16.5 0.0 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KKK15585.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KKK15585.1 - 0.02 14.8 0.0 0.39 10.6 0.0 2.9 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KKK15585.1 - 0.024 14.8 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KKK15585.1 - 0.049 13.9 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KKK15585.1 - 0.054 13.0 0.2 0.15 11.6 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KKK15585.1 - 0.069 12.5 0.7 6.8 6.0 0.0 3.0 2 1 1 3 3 3 0 AAA-like domain IPT PF01745.11 KKK15585.1 - 0.081 12.0 0.1 0.45 9.6 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase zf-CCCH PF00642.19 KKK15586.1 - 4.6e-08 32.5 2.1 8.8e-08 31.6 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KKK15586.1 - 1.2e-07 31.2 4.3 2.1e-07 30.4 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK15586.1 - 1.9e-07 30.9 10.3 3.3e-07 30.2 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK15586.1 - 1.8e-06 27.5 8.7 2.9e-06 26.8 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK15586.1 - 6.9e-06 25.6 10.6 1.2e-05 24.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK15586.1 - 8.1e-06 25.5 7.1 1.4e-05 24.7 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KKK15586.1 - 0.011 15.5 9.1 0.025 14.4 6.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rep_Org_C PF06926.6 KKK15586.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus Uso1_p115_C PF04871.8 KKK15586.1 - 0.039 13.8 2.2 0.039 13.8 1.5 2.3 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-Nse PF11789.3 KKK15586.1 - 0.057 12.9 2.4 0.11 12.0 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KKK15586.1 - 0.12 12.1 5.4 0.28 10.9 3.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Cript PF10235.4 KKK15586.1 - 1.5 9.2 6.5 0.72 10.2 2.5 1.9 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT UCH PF00443.24 KKK15587.1 - 8.8e-69 231.5 0.0 6.3e-68 228.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KKK15587.1 - 1.4e-15 57.4 0.0 5.4e-15 55.6 0.0 2.1 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.1 KKK15587.1 - 2.8e-13 50.0 0.0 1.8e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 KKK15587.1 - 0.002 17.5 0.1 0.005 16.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal Chitin_synth_2 PF03142.10 KKK15588.1 - 1.5e-257 855.2 2.2 2e-257 854.7 1.6 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KKK15588.1 - 2.8e-195 650.3 0.0 3.8e-195 649.9 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KKK15588.1 - 2.3e-19 68.8 0.9 3.8e-18 64.9 0.5 2.6 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KKK15588.1 - 1.8e-17 62.8 0.0 5.3e-13 48.5 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 KKK15588.1 - 2.9e-14 53.4 0.1 1.1e-11 44.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KKK15588.1 - 3.3e-12 46.5 4.9 3.3e-12 46.5 3.4 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KKK15588.1 - 0.00061 19.1 0.0 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KKK15588.1 - 0.0012 18.6 0.0 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 KKK15588.1 - 0.034 14.1 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KKK15588.1 - 0.045 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK15588.1 - 0.078 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Dynactin PF12455.3 KKK15589.1 - 7.1e-96 320.3 7.9 7.1e-96 320.3 5.5 3.4 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 KKK15589.1 - 8.8e-23 79.7 0.1 1.5e-22 79.0 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Sugar_tr PF00083.19 KKK15590.1 - 3.7e-104 348.8 20.2 4.1e-104 348.6 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK15590.1 - 1.5e-21 76.5 27.6 2e-21 76.0 19.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Chorismate_synt PF01264.16 KKK15591.1 - 5.7e-129 429.5 0.0 6.8e-129 429.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.14 KKK15592.1 - 1.8e-16 60.2 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2264 PF10022.4 KKK15593.1 - 2.1e-134 447.7 0.0 2.5e-134 447.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) FAT PF02259.18 KKK15595.1 - 4.6e-130 433.7 0.5 4.6e-130 433.7 0.4 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 KKK15595.1 - 8e-61 204.6 0.8 1.4e-58 197.3 0.2 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 KKK15595.1 - 3.2e-57 193.6 0.3 5.6e-57 192.9 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 KKK15595.1 - 2.7e-41 139.6 4.5 8.2e-41 138.1 0.1 4.0 4 0 0 4 4 4 1 Rapamycin binding domain HEAT_2 PF13646.1 KKK15595.1 - 4.9e-17 62.0 11.3 0.00029 21.0 0.0 9.0 8 2 1 9 9 8 3 HEAT repeats FATC PF02260.15 KKK15595.1 - 2.2e-14 52.5 0.8 5.1e-14 51.4 0.6 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 KKK15595.1 - 3.5e-14 52.8 7.4 0.0052 17.2 0.0 10.6 7 3 3 11 11 11 3 HEAT-like repeat HEAT PF02985.17 KKK15595.1 - 2.6e-10 39.4 22.3 0.31 11.2 0.0 11.7 13 0 0 13 13 12 3 HEAT repeat Adaptin_N PF01602.15 KKK15595.1 - 9.9e-08 30.7 10.2 0.00046 18.6 2.6 4.7 2 2 0 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.3 KKK15595.1 - 0.00019 20.8 1.2 0.96 8.7 0.0 4.7 4 0 0 4 4 4 1 CLASP N terminal MMS19_C PF12460.3 KKK15595.1 - 0.0052 15.5 0.1 0.0052 15.5 0.0 4.2 5 0 0 5 5 5 1 RNAPII transcription regulator C-terminal SH3_1 PF00018.23 KKK15596.1 - 5.6e-10 38.4 0.1 1.5e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK15596.1 - 1.4e-09 37.2 0.0 2.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KKK15596.1 - 6.3e-09 35.2 0.1 1.5e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Nop14 PF04147.7 KKK15596.1 - 1.5 6.6 23.8 3 5.6 16.5 1.4 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.7 KKK15598.1 - 1.5e-163 543.9 0.1 1.3e-162 540.8 0.0 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 KKK15598.1 - 2.2e-99 332.9 0.2 2.2e-99 332.9 0.2 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) HECT PF00632.20 KKK15598.1 - 1.1e-93 313.8 0.0 2e-93 313.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 KKK15598.1 - 1.4e-32 111.8 6.9 1.4e-32 111.8 4.8 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 KKK15598.1 - 0.0068 16.2 0.1 0.025 14.4 0.1 2.1 1 0 0 1 1 1 1 UBA/TS-N domain Pribosyltran_N PF13793.1 KKK15599.1 - 3e-46 155.9 0.8 3.1e-44 149.4 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KKK15599.1 - 3.9e-41 140.8 2.4 1.6e-34 119.3 0.8 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KKK15599.1 - 9.7e-14 51.1 0.4 8.9e-13 48.0 0.3 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KKK15599.1 - 8.6e-06 25.1 0.4 1.6e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 KKK15599.1 - 0.068 12.8 2.7 0.12 12.0 1.8 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C SH3_1 PF00018.23 KKK15615.1 - 2.9e-07 29.7 1.0 2.7e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KKK15615.1 - 0.0001 21.8 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 KKK15616.1 - 4.3e-48 163.7 0.0 6.1e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15616.1 - 3.1e-28 98.5 0.0 6.8e-27 94.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK15616.1 - 0.038 13.7 0.2 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family NtA PF03146.10 KKK15616.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Agrin NtA domain CENP-N PF05238.8 KKK15628.1 - 5.6e-146 486.6 0.0 6.4e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like zf-RING_2 PF13639.1 KKK15629.1 - 3.9e-07 29.7 6.2 6.1e-07 29.1 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KKK15629.1 - 0.0043 16.7 5.9 0.0062 16.2 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KKK15629.1 - 0.016 15.0 5.6 0.027 14.3 3.9 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KKK15629.1 - 0.018 15.1 6.9 0.037 14.1 4.9 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger FANCL_C PF11793.3 KKK15629.1 - 0.023 14.6 7.9 0.07 13.0 5.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KKK15629.1 - 0.033 13.8 6.5 0.085 12.5 4.5 1.8 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 KKK15629.1 - 0.076 12.6 4.9 0.12 12.0 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK15629.1 - 0.22 11.5 7.2 0.37 10.8 5.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KKK15629.1 - 0.29 10.7 7.1 0.47 10.0 4.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KKK15629.1 - 0.88 9.6 8.9 1.9 8.6 6.2 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 KKK15629.1 - 1.3 9.1 5.4 9.4 6.3 4.0 2.1 1 1 1 2 2 2 0 RING-like domain C1_1 PF00130.17 KKK15629.1 - 1.5 8.5 13.2 0.051 13.3 1.9 2.5 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 KKK15629.1 - 6.1 6.6 6.2 11 5.7 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) bZIP_2 PF07716.10 KKK15630.1 - 2.4e-12 46.4 11.4 2.4e-12 46.4 7.9 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KKK15630.1 - 1.5e-05 24.8 9.6 3.6e-05 23.6 6.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2984 PF11203.3 KKK15630.1 - 0.06 13.4 2.6 0.11 12.5 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) Asp PF00026.18 KKK15635.1 - 1.8e-73 247.5 13.2 2.2e-73 247.3 9.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KKK15635.1 - 5.4e-06 26.8 1.5 0.00099 19.5 0.2 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KKK15635.1 - 5.9e-06 26.3 2.3 9.6e-06 25.6 0.6 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KKK15635.1 - 0.072 12.6 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Phosphoesterase PF04185.9 KKK15636.1 - 6.8e-82 275.6 1.4 6.8e-82 275.6 1.0 1.7 2 0 0 2 2 2 1 Phosphoesterase family Fascin PF06268.8 KKK15636.1 - 1.9e-05 24.7 1.4 5.7e-05 23.1 0.2 2.1 1 1 1 2 2 2 1 Fascin domain Cytochrom_D1 PF02239.11 KKK15636.1 - 0.045 12.0 0.0 0.069 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Sugar_tr PF00083.19 KKK15637.1 - 1e-71 241.8 24.9 1.2e-71 241.6 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK15637.1 - 4.7e-18 65.0 39.4 3e-11 42.6 12.7 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KKK15637.1 - 4.6e-05 22.0 5.5 4.6e-05 22.0 3.8 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein G-patch PF01585.18 KKK15666.1 - 1.1e-05 25.0 0.2 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 G-patch domain zf-U1 PF06220.7 KKK15666.1 - 0.21 11.1 1.9 12 5.5 0.1 2.5 2 0 0 2 2 2 0 U1 zinc finger adh_short PF00106.20 KKK15667.1 - 1.7e-11 44.3 0.0 2.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK15667.1 - 6.1e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK15667.1 - 0.00054 19.8 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KKK15667.1 - 0.016 15.2 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 KKK15667.1 - 0.036 12.9 0.1 0.05 12.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 KKK15667.1 - 0.14 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family SUV3_C PF12513.3 KKK15668.1 - 1.1e-15 56.7 0.0 2.3e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KKK15668.1 - 3.2e-10 39.7 0.0 1.2e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TK PF00265.13 KKK15668.1 - 0.096 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase Sec1 PF00995.18 KKK15669.1 - 2.5e-134 449.0 0.0 2.9e-134 448.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1180 PF06679.7 KKK15669.1 - 0.75 9.6 3.5 1.5 8.7 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CorA PF01544.13 KKK15670.1 - 6.2e-44 150.1 0.0 7.6e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.11 KKK15671.1 - 3.1e-36 124.8 26.3 3.1e-36 124.8 18.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KKK15671.1 - 0.14 12.2 3.4 0.16 11.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Med17 PF10156.4 KKK15672.1 - 1.1e-126 422.8 0.0 1.5e-126 422.4 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DAO PF01266.19 KKK15673.1 - 2.1e-46 158.4 0.2 2.5e-46 158.2 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK15673.1 - 0.00054 19.9 0.6 0.0014 18.6 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK15673.1 - 0.0077 16.0 0.1 0.13 12.0 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KKK15673.1 - 0.0079 16.2 0.0 0.29 11.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK15673.1 - 0.0079 15.0 0.7 0.013 14.4 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KKK15673.1 - 0.0096 16.3 0.0 0.067 13.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK15673.1 - 0.038 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK15673.1 - 0.18 10.8 3.4 1.5 7.7 0.3 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Xan_ur_permease PF00860.15 KKK15674.1 - 1.8e-68 230.8 34.0 3e-68 230.1 23.6 1.3 1 0 0 1 1 1 1 Permease family Candida_ALS_N PF11766.3 KKK15675.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding MFS_1 PF07690.11 KKK15676.1 - 7.5e-44 149.8 46.1 3e-43 147.9 31.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK15676.1 - 1.1e-11 43.6 26.3 8.4e-10 37.4 18.2 2.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PBP PF01161.15 KKK15677.1 - 1.4e-16 60.6 0.2 1.7e-16 60.4 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Gly_transf_sug PF04488.10 KKK15678.1 - 0.03 14.7 0.1 0.46 10.8 0.0 2.4 2 1 0 2 2 2 0 Glycosyltransferase sugar-binding region containing DXD motif DUF3052 PF11253.3 KKK15678.1 - 0.044 13.3 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) CoxIIa PF08113.6 KKK15678.1 - 1.2 8.9 5.0 2.9 7.6 3.5 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family CAP59_mtransfer PF11735.3 KKK15679.1 - 6.7e-82 274.3 0.0 9e-82 273.9 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Helicase_C PF00271.26 KKK15680.1 - 6.9e-12 45.0 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 KKK15681.1 - 2.5e-53 180.8 0.0 2.8e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15681.1 - 2.3e-29 102.2 0.0 2.6e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK15681.1 - 0.00014 20.9 0.0 0.00024 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK15681.1 - 0.00067 19.4 0.4 0.003 17.3 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK15681.1 - 0.0023 17.0 0.2 0.0042 16.1 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KKK15681.1 - 0.026 13.3 0.1 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 CrtC PF07143.6 KKK15688.1 - 2.5e-13 50.0 1.3 4.6e-13 49.1 0.9 1.5 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) CoA_transf_3 PF02515.12 KKK15689.1 - 6e-30 103.8 0.2 1.9e-29 102.2 0.0 1.8 2 0 0 2 2 2 1 CoA-transferase family III Aconitase PF00330.15 KKK15690.1 - 9e-157 522.2 0.0 3.9e-156 520.1 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KKK15690.1 - 2.8e-39 134.2 0.0 4.3e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain PH_4 PF15404.1 KKK15692.1 - 1e-56 191.4 1.8 1.8e-55 187.3 0.1 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.1 KKK15692.1 - 5.3e-21 73.8 0.5 1.5e-20 72.4 0.4 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 KKK15692.1 - 8.1e-10 38.8 4.7 6.6e-06 26.2 0.0 3.9 4 0 0 4 4 4 2 PH domain PH_6 PF15406.1 KKK15692.1 - 0.0018 18.3 0.1 3.2 7.8 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain DUF1992 PF09350.5 KKK15692.1 - 0.012 15.4 1.5 0.19 11.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1992) GLTP PF08718.6 KKK15693.1 - 4.3e-45 153.3 0.0 5.8e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) BMC PF00936.14 KKK15693.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 BMC domain Macro PF01661.16 KKK15694.1 - 1.9e-39 134.1 0.1 2.9e-39 133.6 0.1 1.3 1 0 0 1 1 1 1 Macro domain Peptidase_S24 PF00717.18 KKK15695.1 - 1.8e-05 24.2 0.0 7.7e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KKK15695.1 - 0.00077 18.9 0.0 0.17 11.3 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 IMS PF00817.15 KKK15700.1 - 3.5e-34 117.7 0.0 1.3e-32 112.6 0.0 2.2 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KKK15700.1 - 2.7e-13 49.9 0.0 4.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KKK15700.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif DUF765 PF05570.6 KKK15700.1 - 0.064 13.2 1.5 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) Nuc_sug_transp PF04142.10 KKK15702.1 - 2.1e-25 89.2 10.0 2.1e-25 89.2 6.9 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 KKK15702.1 - 7.6e-06 26.1 4.1 7.6e-06 26.1 2.8 3.8 2 2 1 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 KKK15702.1 - 9.7e-06 24.7 16.4 1.3e-05 24.3 10.4 1.8 1 1 1 2 2 2 1 UAA transporter family ASFV_J13L PF05568.6 KKK15702.1 - 0.24 10.9 2.1 1.4 8.4 0.0 2.6 3 0 0 3 3 3 0 African swine fever virus J13L protein MFS_1 PF07690.11 KKK15703.1 - 1.3e-36 126.1 54.4 1.6e-34 119.2 22.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2614 PF11023.3 KKK15703.1 - 2.7 7.8 6.0 0.97 9.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) VWA PF00092.23 KKK15704.1 - 1.8e-06 27.7 0.0 3.7e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KKK15704.1 - 0.00029 20.9 0.0 0.0009 19.3 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Fungal_trans_2 PF11951.3 KKK15706.1 - 9.8e-11 40.8 0.0 1.7e-10 40.1 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK15710.1 - 0.0028 17.9 3.6 17 5.9 0.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK15710.1 - 0.0034 17.6 2.6 2 8.9 0.0 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK15710.1 - 0.0076 16.4 2.6 0.62 10.4 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain ATP-synt_D PF01813.12 KKK15711.1 - 2.5e-65 219.7 1.8 3.5e-65 219.2 1.3 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Nup54 PF13874.1 KKK15711.1 - 0.96 9.1 5.9 1.3 8.6 0.2 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 TPR_12 PF13424.1 KKK15712.1 - 3.5e-11 42.8 2.5 0.057 13.3 0.0 7.5 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK15712.1 - 4.7e-11 42.2 14.9 1.9 9.3 0.0 10.8 11 2 2 13 13 10 3 Tetratricopeptide repeat Suf PF05843.9 KKK15712.1 - 6.8e-11 42.4 11.9 0.029 14.1 0.0 6.2 3 2 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KKK15712.1 - 5.8e-08 32.9 0.3 2.1 8.7 0.0 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK15712.1 - 1.5e-07 30.9 5.0 0.42 10.2 0.0 6.7 8 1 0 8 8 8 2 TPR repeat TPR_2 PF07719.12 KKK15712.1 - 2.3e-06 27.0 11.6 0.96 9.5 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KKK15712.1 - 8.9e-06 25.5 15.0 1.7 8.4 0.1 7.1 7 1 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 KKK15712.1 - 2.4e-05 23.7 5.6 1.9 8.4 0.0 6.7 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK15712.1 - 3.7e-05 24.2 9.6 0.13 12.9 0.0 6.6 7 1 1 8 8 8 2 Tetratricopeptide repeat NRDE-2 PF08424.5 KKK15712.1 - 6.5e-05 21.9 12.6 0.021 13.7 0.1 5.4 3 2 3 6 6 6 3 NRDE-2, necessary for RNA interference TPR_7 PF13176.1 KKK15712.1 - 0.00015 21.2 3.1 11 6.1 0.0 7.2 6 1 1 7 7 7 0 Tetratricopeptide repeat HAT PF02184.11 KKK15712.1 - 0.011 15.4 1.9 2.4 8.0 0.0 5.3 5 0 0 5 5 4 0 HAT (Half-A-TPR) repeat TPR_17 PF13431.1 KKK15712.1 - 0.013 15.6 5.4 1.8 8.9 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KKK15712.1 - 0.083 12.5 0.2 37 4.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.17 KKK15713.1 - 8e-12 44.6 0.0 1.2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK15713.1 - 3.1e-08 33.4 0.0 4.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK15713.1 - 4.3e-06 26.4 0.0 6.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.1 KKK15714.1 - 6.2e-08 32.4 10.4 1.1e-05 25.3 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK15714.1 - 1.6e-07 31.2 9.5 5.8e-06 26.3 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK15714.1 - 6.2e-06 26.2 2.3 6.2e-06 26.2 1.6 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.2 KKK15714.1 - 0.00014 21.9 8.7 0.00057 19.9 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF2225 PF09986.4 KKK15714.1 - 0.00099 18.6 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 KKK15714.1 - 0.0051 16.9 0.9 0.0051 16.9 0.6 2.0 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KKK15714.1 - 0.0061 16.6 6.4 0.012 15.7 4.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.6 KKK15714.1 - 0.04 14.1 1.3 0.053 13.7 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) GnHR_trans PF12369.3 KKK15714.1 - 0.059 13.8 0.4 0.17 12.3 0.3 1.7 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region PRP21_like_P PF12230.3 KKK15714.1 - 0.071 12.6 0.7 0.095 12.1 0.5 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_2 PF12756.2 KKK15714.1 - 0.085 12.9 1.9 0.14 12.3 1.3 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KKK15714.1 - 0.29 10.9 6.4 0.61 9.8 4.4 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.1 KKK15714.1 - 0.48 10.3 4.0 2.1 8.3 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger RGS PF00615.14 KKK15715.1 - 1.1e-34 119.0 0.1 2.4e-34 117.9 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KKK15715.1 - 1.6e-21 75.8 0.0 9.6e-18 63.7 0.0 2.6 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73 PF05179.9 KKK15716.1 - 9.2e-41 139.9 0.2 8.6e-40 136.8 0.1 2.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Glyco_hydro_61 PF03443.9 KKK15717.1 - 4.6e-78 261.9 0.0 5.4e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TRAM_LAG1_CLN8 PF03798.11 KKK15718.1 - 2.8e-42 144.5 23.4 2.8e-42 144.5 16.2 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KKK15718.1 - 4.9e-19 67.5 0.1 9.7e-19 66.6 0.0 1.5 1 0 0 1 1 1 1 TRAM1-like protein DUF383 PF04063.9 KKK15719.1 - 1e-31 109.9 8.3 1.2e-28 99.9 0.0 3.5 3 1 1 4 4 4 2 Domain of unknown function (DUF383) DUF384 PF04064.8 KKK15719.1 - 2e-23 81.6 0.3 5e-23 80.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) TFIIF_alpha PF05793.7 KKK15719.1 - 3.1e-06 25.8 68.0 1.8e-05 23.3 40.6 3.9 1 1 2 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AsiA PF09010.5 KKK15719.1 - 0.045 13.6 0.2 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Anti-Sigma Factor A Histidinol_dh PF00815.15 KKK15720.1 - 3.6e-117 391.4 0.0 4.5e-117 391.1 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase FAD_binding_3 PF01494.14 KKK15721.1 - 3.3e-24 85.6 0.0 5.2e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK15721.1 - 6.8e-08 32.4 0.2 1.8e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK15721.1 - 9.4e-08 31.3 0.2 3.1e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase ADC PF06314.6 KKK15721.1 - 2.4e-07 30.3 0.0 6.6e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_2 PF00890.19 KKK15721.1 - 7.7e-06 25.0 0.5 1.2e-05 24.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK15721.1 - 1.4e-05 25.0 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK15721.1 - 0.00015 22.1 0.3 0.00085 19.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KKK15721.1 - 0.00025 19.8 0.5 0.0092 14.6 0.1 2.6 3 0 0 3 3 3 1 Tryptophan halogenase GIDA PF01134.17 KKK15721.1 - 0.0015 17.4 0.1 0.0023 16.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KKK15721.1 - 0.0016 18.5 0.1 0.0037 17.3 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK15721.1 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KKK15721.1 - 0.0036 16.4 0.1 1.6 7.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KKK15721.1 - 0.0038 15.7 0.1 0.007 14.8 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KKK15721.1 - 0.005 16.4 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KKK15721.1 - 0.012 14.6 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KKK15721.1 - 0.02 14.6 0.6 0.072 12.8 0.4 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KKK15721.1 - 0.21 11.2 0.1 0.33 10.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KKK15721.1 - 0.33 9.8 0.9 9.6 5.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.20 KKK15722.1 - 9.6e-16 58.1 0.1 1.8e-14 54.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK15722.1 - 4.6e-09 36.1 0.0 1.5e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KKK15722.1 - 0.0012 17.8 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KKK15722.1 - 0.0029 17.0 0.0 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KKK15722.1 - 0.0087 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.8 KKK15722.1 - 0.011 15.1 0.0 2.5 7.4 0.0 2.7 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family DUF3940 PF13076.1 KKK15722.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) Saccharop_dh PF03435.13 KKK15722.1 - 0.095 11.6 0.0 5 5.9 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase Rad4 PF03835.10 KKK15723.1 - 2.5e-14 52.8 4.6 5.7e-14 51.7 3.2 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KKK15723.1 - 7.2e-13 48.7 2.0 1.8e-12 47.4 1.4 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF1469 PF07332.6 KKK15724.1 - 0.0093 15.6 0.3 0.0093 15.6 0.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1469) Microcin PF03526.8 KKK15724.1 - 0.17 11.5 0.9 0.35 10.5 0.2 1.8 2 0 0 2 2 2 0 Colicin E1 (microcin) immunity protein NPCC PF08058.6 KKK15724.1 - 0.35 10.7 2.5 0.53 10.1 0.1 2.4 3 0 0 3 3 3 0 Nuclear pore complex component Aldedh PF00171.17 KKK15725.1 - 1.3e-128 429.2 0.0 1.6e-128 428.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KKK15725.1 - 6.9e-07 28.3 0.0 1.5e-06 27.1 0.0 1.4 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KKK15725.1 - 0.00086 18.5 0.1 0.006 15.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) MoCF_biosynth PF00994.19 KKK15726.1 - 1e-41 141.6 0.0 1.7e-24 85.8 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KKK15726.1 - 8.7e-33 112.9 1.2 1.3e-32 112.4 0.8 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KKK15726.1 - 1.7e-16 59.9 0.1 4.2e-16 58.6 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) XPA_C PF05181.7 KKK15727.1 - 3.6e-29 100.1 3.6 3.6e-29 100.1 2.5 1.9 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 KKK15727.1 - 0.00042 19.9 3.9 0.00042 19.9 2.7 2.1 2 0 0 2 2 2 1 XPA protein N-terminal YhfH PF14149.1 KKK15727.1 - 0.41 10.4 11.6 0.28 10.9 0.7 2.6 2 0 0 2 2 2 0 YhfH-like protein zf-DHHC PF01529.15 KKK15727.1 - 2.2 7.6 4.5 4.1 6.7 3.1 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase ArfGap PF01412.13 KKK15727.1 - 4.4 7.1 8.4 1.1 9.0 0.9 2.8 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf DUF2235 PF09994.4 KKK15728.1 - 4e-77 259.2 0.0 5.2e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) WD40 PF00400.27 KKK15729.1 - 5e-29 99.1 3.9 3.9e-07 29.6 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat HIRA_B PF09453.5 KKK15729.1 - 1.4e-05 24.5 0.1 4.9e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.6 KKK15729.1 - 0.0018 17.9 0.9 0.073 12.7 0.0 2.9 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A YrhK PF14145.1 KKK15729.1 - 0.3 10.7 16.0 2.1 8.0 0.3 4.1 2 2 1 3 3 3 0 YrhK-like protein FSH1 PF03959.8 KKK15730.1 - 3.8e-25 88.5 0.0 4.5e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KKK15730.1 - 3.2e-05 23.7 0.1 4.7e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK15730.1 - 0.11 12.0 0.1 11 5.4 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.20 KKK15732.1 - 6.5e-25 87.9 1.3 8.7e-25 87.5 0.3 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK15732.1 - 8.5e-21 74.8 0.0 1.1e-20 74.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK15732.1 - 2e-09 37.3 0.3 3.1e-09 36.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK15732.1 - 0.0048 16.3 0.0 0.0099 15.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KKK15732.1 - 0.098 13.0 0.1 0.27 11.6 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UNC-50 PF05216.8 KKK15732.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 UNC-50 family Cupin_2 PF07883.6 KKK15733.1 - 1.3e-09 37.4 0.0 1.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KKK15733.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Ribosomal_S4 PF00163.14 KKK15733.1 - 0.071 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Cupin_1 PF00190.17 KKK15733.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Cupin DHHA2 PF02833.9 KKK15734.1 - 3.1e-19 69.4 0.0 4.4e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KKK15734.1 - 1.5e-07 31.1 0.1 3.1e-06 26.8 0.1 2.3 1 1 0 1 1 1 1 DHH family Rad21_Rec8_N PF04825.8 KKK15735.1 - 9.4e-30 102.8 0.0 1.7e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein adh_short PF00106.20 KKK15736.1 - 9e-20 71.2 0.2 1.7e-19 70.3 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK15736.1 - 1.1e-06 28.4 0.2 2.7e-06 27.1 0.1 1.7 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KKK15736.1 - 0.0011 19.0 0.0 0.0032 17.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK15736.1 - 0.0023 17.3 0.0 0.0032 16.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KKK15736.1 - 0.012 15.3 0.3 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Transp_cyt_pur PF02133.10 KKK15737.1 - 4.5e-21 74.9 36.5 7.1e-21 74.2 25.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Myb_DNA-binding PF00249.26 KKK15738.1 - 3e-12 46.4 5.3 3.2e-07 30.3 2.1 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK15738.1 - 8.5e-10 38.5 1.4 1.2e-06 28.4 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Ribosomal_L34e PF01199.13 KKK15739.1 - 1.4e-37 127.7 2.9 2.6e-37 126.9 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L34e EndIII_4Fe-2S PF10576.4 KKK15739.1 - 0.7 10.1 3.0 24 5.3 0.1 3.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III PROCN PF08083.6 KKK15740.1 - 8.7e-224 742.4 8.3 1.5e-223 741.6 5.7 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KKK15740.1 - 1.4e-124 413.8 1.5 2.5e-124 413.1 1.0 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KKK15740.1 - 2.2e-101 335.9 0.2 2.9e-62 208.7 0.1 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KKK15740.1 - 2.4e-77 257.7 3.1 4.2e-77 256.9 1.3 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KKK15740.1 - 1.9e-67 225.0 0.1 5.3e-67 223.5 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 KKK15740.1 - 1.2e-52 178.7 7.0 3.5e-31 108.6 0.0 3.3 2 1 1 3 3 3 2 Hom_end-associated Hint PROCT PF08084.6 KKK15740.1 - 3.5e-45 152.7 0.0 9.4e-45 151.3 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 KKK15740.1 - 1.1e-44 150.1 0.2 3.2e-44 148.7 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hint_2 PF13403.1 KKK15740.1 - 0.011 15.7 0.0 0.046 13.6 0.0 2.0 1 1 0 1 1 1 0 Hint domain OCD_Mu_crystall PF02423.10 KKK15740.1 - 0.082 11.6 1.0 0.15 10.7 0.7 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF3753 PF12575.3 KKK15740.1 - 0.092 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Myb_DNA-bind_6 PF13921.1 KKK15741.1 - 1.4e-13 50.6 0.0 4.4e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK15741.1 - 1.3e-10 41.1 0.1 2.6e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain COX5B PF01215.14 KKK15742.1 - 6.9e-36 122.9 0.0 1e-35 122.3 0.0 1.2 1 1 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_L17 PF01196.14 KKK15743.1 - 4.2e-12 46.4 0.0 7.6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 SUZ PF12752.2 KKK15744.1 - 5.8e-20 71.5 3.0 5.8e-20 71.5 2.1 2.3 2 0 0 2 2 2 1 SUZ domain Pmp3 PF01679.12 KKK15745.1 - 4.6e-26 90.2 6.0 5e-26 90.1 4.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DctM PF06808.7 KKK15745.1 - 0.055 12.0 0.1 0.06 11.9 0.1 1.0 1 0 0 1 1 1 0 DctM-like transporters CFEM PF05730.6 KKK15746.1 - 0.027 14.2 4.1 0.051 13.3 2.8 1.4 1 0 0 1 1 1 0 CFEM domain DAP10 PF07213.6 KKK15746.1 - 0.035 13.8 0.0 0.095 12.4 0.0 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Asp PF00026.18 KKK15747.1 - 1.7e-08 34.1 4.7 2.5e-08 33.5 3.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Vpu PF00558.14 KKK15747.1 - 0.0094 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Vpu protein SKG6 PF08693.5 KKK15747.1 - 0.024 13.9 2.0 0.081 12.2 1.4 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.8 KKK15747.1 - 0.035 12.7 0.4 0.035 12.7 0.3 2.0 2 0 0 2 2 2 0 Giardia variant-specific surface protein DUF2029 PF09594.5 KKK15747.1 - 0.055 12.9 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Herpes_gE PF02480.11 KKK15747.1 - 0.1 10.8 0.0 0.19 9.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RNase_T PF00929.19 KKK15748.1 - 1.7e-07 31.6 0.0 1.6e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Exonuclease Hydrolase_6 PF13344.1 KKK15749.1 - 7.9e-22 77.0 0.0 1.5e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK15749.1 - 2.8e-11 42.9 0.0 9.6e-10 38.0 0.0 3.0 4 0 0 4 4 4 1 HAD-hyrolase-like HAD_2 PF13419.1 KKK15749.1 - 0.093 12.9 0.0 20 5.3 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK15749.1 - 0.1 12.9 0.0 0.74 10.1 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF676 PF05057.9 KKK15750.1 - 6.2e-48 162.9 0.0 9.1e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KKK15750.1 - 4.3e-07 30.0 0.1 8.5e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK15750.1 - 1.4e-05 24.9 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK15750.1 - 2.2e-05 24.1 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KKK15750.1 - 0.0051 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KKK15750.1 - 0.024 14.1 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 KKK15750.1 - 0.063 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 KKK15750.1 - 0.099 11.7 0.0 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L22e PF01776.12 KKK15751.1 - 1.6e-50 169.8 0.5 1.9e-50 169.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Meth_synt_2 PF01717.13 KKK15752.1 - 1e-19 70.6 0.0 9e-19 67.5 0.0 2.0 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KKK15752.1 - 0.00012 21.5 0.0 0.015 14.5 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain DUF1713 PF08213.6 KKK15753.1 - 1.1e-12 47.3 20.7 2.1e-12 46.4 14.4 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KKK15753.1 - 0.0011 18.8 0.0 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial protein Pet20 G-alpha PF00503.15 KKK15754.1 - 3.1e-114 381.6 0.1 3.8e-114 381.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KKK15754.1 - 4.4e-14 52.1 0.5 1.9e-09 36.9 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK15754.1 - 3.2e-07 29.7 0.1 0.0023 17.1 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK15754.1 - 0.0076 16.7 0.0 0.48 10.9 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KKK15754.1 - 0.021 14.7 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KKK15754.1 - 0.037 13.5 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KKK15754.1 - 0.065 12.6 0.0 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP-synt_C PF00137.16 KKK15756.1 - 4.5e-32 109.7 29.8 7.9e-18 64.1 8.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 KKK15756.1 - 0.14 11.7 3.9 0.055 13.0 0.7 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A RepB PF07506.6 KKK15770.1 - 4.6 7.0 7.0 0.39 10.5 1.5 1.5 2 0 0 2 2 2 0 RepB plasmid partitioning protein CN_hydrolase PF00795.17 KKK15776.1 - 1e-30 106.4 0.0 1.8e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KKK15776.1 - 1.9e-23 82.6 0.0 1.2e-22 80.0 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KKK15776.1 - 0.023 14.2 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase NUDIX-like PF09296.6 KKK15777.1 - 9.3e-21 74.0 0.1 1.9e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 KKK15777.1 - 4.8e-15 55.4 0.1 8.9e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 KKK15777.1 - 0.004 16.6 2.1 0.0072 15.8 1.4 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain V-SNARE_C PF12352.3 KKK15777.1 - 0.045 13.8 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus POT1 PF02765.12 KKK15778.1 - 6.9e-11 42.2 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 HDA2-3 PF11496.3 KKK15779.1 - 3.8e-54 183.5 0.0 7.4e-54 182.5 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 FMO-like PF00743.14 KKK15779.1 - 4e-32 111.1 0.0 2.2e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KKK15779.1 - 7.2e-11 42.5 0.1 5.4e-10 39.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK15779.1 - 1.9e-07 30.3 0.9 5.1e-07 28.9 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KKK15779.1 - 1.3e-06 28.4 0.1 3.8e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GAS PF13851.1 KKK15779.1 - 0.0025 17.0 6.8 0.0025 17.0 4.7 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF2422 PF10337.4 KKK15779.1 - 2.2 6.9 6.3 4 6.1 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Sec20 PF03908.8 KKK15779.1 - 2.8 7.6 7.2 11 5.8 2.0 3.0 1 1 1 2 2 2 0 Sec20 T2SF PF00482.18 KKK15779.1 - 5.4 6.9 8.5 1.1 9.1 1.5 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F V_ATPase_I PF01496.14 KKK15779.1 - 7.1 4.3 18.5 14 3.3 12.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ketoacyl-synt PF00109.21 KKK15780.1 - 1.6e-78 263.6 0.0 6.2e-77 258.4 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK15780.1 - 3.3e-55 187.6 2.2 5.4e-54 183.6 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KKK15780.1 - 9.2e-34 115.8 1.6 2.5e-33 114.4 0.3 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KKK15780.1 - 1.9e-27 96.9 0.0 3.8e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KKK15780.1 - 1.1e-25 89.6 5.0 3.6e-13 49.5 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thiolase_N PF00108.18 KKK15780.1 - 1.7e-05 23.9 0.1 4.8e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Spore_III_AF PF09581.5 KKK15780.1 - 0.42 10.4 0.0 0.77 9.5 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Cu-oxidase_3 PF07732.10 KKK15781.1 - 7.2e-41 138.6 1.6 2.9e-40 136.6 1.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK15781.1 - 2.7e-27 94.9 10.3 4.4e-22 78.0 0.5 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK15781.1 - 1.2e-21 77.2 0.0 3.4e-19 69.2 0.0 2.8 2 1 0 2 2 2 2 Multicopper oxidase SH3_2 PF07653.12 KKK15782.1 - 6.6e-10 38.3 0.1 1.2e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK15782.1 - 1.9e-07 30.3 0.0 2.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK15782.1 - 6.7e-07 28.7 0.1 1.1e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain MTD PF01993.13 KKK15782.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Ferric_reduct PF01794.14 KKK15783.1 - 1e-20 74.0 9.6 1e-20 74.0 6.7 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KKK15783.1 - 9.9e-15 54.3 0.1 5.7e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 KKK15783.1 - 0.0035 17.2 0.0 0.27 11.1 0.0 3.0 2 1 1 3 3 3 1 Ferric reductase NAD binding domain bZIP_1 PF00170.16 KKK15784.1 - 3.9e-05 23.5 11.9 5.2e-05 23.1 8.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK15784.1 - 7e-05 22.5 12.5 0.00012 21.8 8.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK15784.1 - 0.0016 18.6 9.3 0.0023 18.2 6.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor NinG PF05766.7 KKK15784.1 - 0.072 12.8 1.6 0.092 12.4 1.1 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DivIC PF04977.10 KKK15784.1 - 0.39 10.2 5.1 0.14 11.6 1.3 1.9 1 1 1 2 2 2 0 Septum formation initiator ABC2_membrane PF01061.19 KKK15785.1 - 4.8e-20 71.6 10.8 4.8e-20 71.6 7.5 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 KKK15785.1 - 0.00013 21.0 6.0 0.00022 20.3 4.2 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.7 KKK15785.1 - 0.012 15.3 0.3 0.012 15.3 0.2 2.0 2 0 0 2 2 2 0 CDR ABC transporter Hum_adeno_E3A PF05393.6 KKK15785.1 - 0.08 12.6 1.6 0.12 12.0 0.4 1.8 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein OppC_N PF12911.2 KKK15785.1 - 3.1 7.2 9.0 3.9 6.9 0.1 3.4 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Fungal_trans PF04082.13 KKK15787.1 - 1.2e-14 53.8 0.4 2.1e-14 53.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15787.1 - 0.013 15.4 1.0 0.013 15.4 0.7 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MerR-DNA-bind PF09278.6 KKK15787.1 - 0.23 11.9 0.0 0.23 11.9 0.0 2.5 3 0 0 3 3 3 0 MerR, DNA binding adh_short PF00106.20 KKK15788.1 - 1.9e-19 70.1 0.0 4e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.13 KKK15788.1 - 3.5e-14 52.3 0.0 1.5e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 KKK15788.1 - 4.4e-13 49.5 0.0 7e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK15788.1 - 6.5e-06 25.9 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 KR domain PNTB PF02233.11 KKK15792.1 - 1.1e-171 571.7 22.3 1.1e-171 571.7 15.4 1.6 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KKK15792.1 - 1.9e-54 183.7 0.6 3.4e-54 182.9 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KKK15792.1 - 9.4e-46 155.1 0.0 2.2e-45 154.0 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KKK15792.1 - 8.6e-19 67.5 6.9 8.6e-19 67.5 4.8 6.1 4 3 2 6 6 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KKK15792.1 - 3.5e-05 23.0 0.2 0.34 10.0 0.0 2.7 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KKK15792.1 - 0.0015 18.0 0.1 0.0051 16.3 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KKK15792.1 - 0.0068 15.9 0.0 0.057 13.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain TPP_enzyme_M PF00205.17 KKK15792.1 - 0.04 13.6 0.3 0.23 11.2 0.2 2.3 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.9 KKK15792.1 - 0.042 13.7 0.6 0.1 12.4 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 KKK15792.1 - 0.046 14.2 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 KKK15792.1 - 0.19 11.8 7.7 4.1 7.5 0.0 4.5 5 1 0 5 5 5 0 Shikimate / quinate 5-dehydrogenase Fungal_trans_2 PF11951.3 KKK15793.1 - 3.2e-36 124.7 0.2 4.1e-36 124.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15793.1 - 6.7e-09 35.5 8.2 1.2e-08 34.7 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 KKK15794.1 - 4.5e-23 81.4 45.9 8.7e-21 73.9 24.9 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 KKK15794.1 - 5.1e-09 34.9 25.8 5.1e-09 34.9 17.9 1.6 2 0 0 2 2 2 1 Amino acid permease Fungal_trans PF04082.13 KKK15795.1 - 6.7e-12 44.8 0.1 5.7e-11 41.7 0.0 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15795.1 - 4e-09 36.2 13.3 7.5e-09 35.3 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 KKK15796.1 - 2.7e-31 109.2 0.0 3.5e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK15796.1 - 2.1e-30 105.8 0.0 2.8e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK15796.1 - 7.3e-08 32.2 0.0 1.8e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK15796.1 - 0.0022 17.4 0.0 0.0077 15.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KKK15796.1 - 0.0096 15.6 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 KKK15796.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.14 KKK15796.1 - 0.087 11.5 0.1 0.13 10.8 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.16 KKK15796.1 - 0.092 12.5 0.1 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_32 PF13679.1 KKK15797.1 - 1.1e-21 76.9 0.6 3.3e-21 75.4 0.4 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK15797.1 - 0.012 16.1 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KKK15797.1 - 0.07 12.7 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Syntaxin-6_N PF09177.6 KKK15799.1 - 2.9e-24 85.3 0.2 1.8e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KKK15799.1 - 4.9e-14 51.7 2.4 4.9e-14 51.7 1.6 2.8 3 0 0 3 3 3 1 SNARE domain Reo_sigmaC PF04582.7 KKK15799.1 - 0.089 11.9 0.1 0.62 9.1 0.0 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KKK15799.1 - 0.18 11.3 0.0 0.18 11.3 0.0 3.0 3 0 0 3 3 3 0 IncA protein TBPIP PF07106.8 KKK15799.1 - 0.34 10.4 2.3 1.6 8.2 0.1 2.3 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 KKK15799.1 - 0.72 10.2 3.4 5.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF1515 PF07439.6 KKK15799.1 - 4.9 7.0 6.3 41 4.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) NAP PF00956.13 KKK15800.1 - 3.8e-46 157.1 10.4 3.8e-46 157.1 7.2 1.9 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) Med8 PF10232.4 KKK15800.1 - 0.013 15.0 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 NmrA PF05368.8 KKK15801.1 - 2e-68 230.1 0.0 2.5e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK15801.1 - 8.1e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding PTR2 PF00854.16 KKK15802.1 - 1.2e-55 188.8 8.2 1.9e-55 188.1 5.7 1.4 1 0 0 1 1 1 1 POT family Maf1 PF09174.5 KKK15803.1 - 1e-65 220.9 0.1 1.6e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 KKK15803.1 - 1.8e-33 115.2 0.2 3e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3969 PF13108.1 KKK15803.1 - 0.061 12.9 0.6 1.5 8.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3969) IncA PF04156.9 KKK15804.1 - 0.00039 20.0 6.9 0.00039 20.0 4.8 5.0 3 1 2 5 5 5 1 IncA protein Filament PF00038.16 KKK15804.1 - 0.003 17.1 30.9 0.003 17.1 21.4 4.1 4 2 0 4 4 4 1 Intermediate filament protein Reo_sigmaC PF04582.7 KKK15804.1 - 0.7 9.0 11.9 0.44 9.6 3.8 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 KKK15804.1 - 3.7 6.7 62.5 0.026 13.7 6.5 4.9 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KKK15804.1 - 7.8 6.2 59.7 0.28 10.9 7.0 4.5 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.2 KKK15804.1 - 8.1 5.6 54.7 1.6 7.9 12.9 4.7 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain COPIIcoated_ERV PF07970.7 KKK15806.1 - 4.4e-21 75.5 0.1 1.7e-19 70.3 0.1 2.0 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Fungal_trans_2 PF11951.3 KKK15809.1 - 6.4e-09 34.8 0.6 8.3e-09 34.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tcf25 PF04910.9 KKK15812.1 - 4.6e-90 302.1 0.0 8.2e-90 301.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_16 PF13432.1 KKK15812.1 - 0.00084 19.9 1.4 0.06 14.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK15812.1 - 0.0056 17.2 0.9 0.28 11.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK15812.1 - 0.014 15.0 0.4 0.1 12.2 0.1 2.4 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 KKK15812.1 - 0.018 14.8 1.1 0.052 13.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SR-25 PF10500.4 KKK15812.1 - 2.6 7.4 12.9 0.1 12.0 3.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PP2C PF00481.16 KKK15813.1 - 3.3e-44 151.2 0.0 5.9e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KKK15813.1 - 1.6e-06 27.7 0.1 3.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KKK15813.1 - 4.9e-05 23.1 0.1 0.21 11.2 0.0 2.9 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PQ-loop PF04193.9 KKK15814.1 - 2.2e-40 135.9 6.9 1.1e-21 76.0 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat FTR1 PF03239.9 KKK15814.1 - 1.4 7.7 5.5 1.8 7.4 1.9 2.1 2 0 0 2 2 2 0 Iron permease FTR1 family DUF1187 PF06688.6 KKK15815.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1187) Ribosomal_L18e PF00828.14 KKK15829.1 - 2.6e-13 50.4 2.4 1.3e-12 48.1 1.6 2.1 1 1 0 1 1 1 1 Ribosomal protein L18e/L15 GntR PF00392.16 KKK15829.1 - 0.094 12.1 0.1 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Cyclin PF08613.6 KKK15830.1 - 5.7e-17 62.5 0.0 8.6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KKK15830.1 - 0.00011 21.7 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pal1 PF08316.6 KKK15831.1 - 2.2e-47 161.0 0.6 6.3e-47 159.5 0.4 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein Beta_elim_lyase PF01212.16 KKK15843.1 - 3.4e-39 134.7 0.1 4.4e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.13 KKK15843.1 - 9.7e-07 27.9 0.2 1.5e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15843.1 - 0.0004 20.2 8.0 0.00077 19.3 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 KKK15843.1 - 0.00056 18.9 0.0 0.00086 18.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KKK15843.1 - 0.00075 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 KKK15843.1 - 0.013 13.8 0.1 0.018 13.3 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase tRNA-synt_1c PF00749.16 KKK15844.1 - 1.8e-94 315.9 0.0 2.3e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain FAD_binding_4 PF01565.18 KKK15845.1 - 7.9e-21 73.9 2.7 1.4e-20 73.1 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK15845.1 - 1.4e-06 28.1 0.1 3.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like PseudoU_synth_2 PF00849.17 KKK15846.1 - 2.4e-26 92.4 0.0 3.7e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 KKK15846.1 - 0.00096 18.5 0.1 0.0019 17.5 0.1 1.5 1 0 0 1 1 1 1 S4 domain GFA PF04828.9 KKK15846.1 - 0.041 13.8 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme 4HBT PF03061.17 KKK15848.1 - 7.9e-14 51.5 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KKK15848.1 - 3.1e-05 24.4 0.0 4.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 KKK15848.1 - 0.00096 18.1 0.3 0.0014 17.6 0.2 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase ILVD_EDD PF00920.16 KKK15849.1 - 1.7e-150 501.9 0.0 2.3e-150 501.5 0.0 1.2 1 0 0 1 1 1 1 Dehydratase family DnaJ PF00226.26 KKK15849.1 - 4.5e-22 77.5 1.5 1.9e-21 75.5 1.2 2.0 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 KKK15849.1 - 1e-20 73.4 0.2 3.7e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KKK15849.1 - 7e-13 48.4 16.3 7e-13 48.4 11.3 2.0 2 0 0 2 2 2 1 DnaJ central domain SHOCT PF09851.4 KKK15849.1 - 0.24 10.9 4.4 5.8 6.5 0.0 3.0 2 0 0 2 2 2 0 Short C-terminal domain HypA PF01155.14 KKK15849.1 - 6.3 6.5 10.9 4.2 7.1 1.5 2.4 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Mito_carr PF00153.22 KKK15851.1 - 4.4e-28 96.8 1.9 2.8e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Atg8 PF02991.11 KKK15852.1 - 3.1e-47 158.8 1.0 4.7e-47 158.2 0.4 1.4 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KKK15852.1 - 5.8e-05 23.2 0.1 9.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 KKK15853.1 - 2e-121 404.0 0.0 6.5e-121 402.4 0.0 1.7 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Acyl_transf_1 PF00698.16 KKK15868.1 - 2e-57 194.9 0.0 2.7e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KKK15868.1 - 7.4e-26 90.3 0.2 1.9e-25 89.0 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KKK15868.1 - 1e-05 24.8 0.3 1.8e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase DUF915 PF06028.6 KKK15868.1 - 0.22 10.6 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Catalase PF00199.14 KKK15876.1 - 1.2e-157 524.5 0.5 1.5e-157 524.1 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KKK15876.1 - 8.3e-17 60.8 0.0 2e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Hs1pro-1_C PF07014.7 KKK15876.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Pro_dh PF01619.13 KKK15877.1 - 6e-36 124.0 0.0 9.5e-36 123.3 0.0 1.4 1 1 0 1 1 1 1 Proline dehydrogenase AAA_assoc PF14363.1 KKK15877.1 - 0.0078 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Domain associated at C-terminal with AAA IMS_C PF11799.3 KKK15877.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain TrmE_N PF10396.4 KKK15877.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Glyco_hydro_65m PF03632.10 KKK15878.1 - 6.9e-95 317.8 1.1 3.1e-94 315.7 0.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KKK15878.1 - 3.8e-55 186.9 0.0 6.2e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 KKK15878.1 - 1.5e-06 28.2 0.1 3e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain LEF-8 PF04941.7 KKK15878.1 - 0.5 7.9 0.1 0.74 7.4 0.1 1.1 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) Kin17_mid PF10357.4 KKK15880.1 - 1.2e-49 167.1 2.4 1.2e-49 167.1 1.6 2.0 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 KKK15880.1 - 0.0001 22.2 1.5 0.00022 21.2 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK15880.1 - 0.0015 18.6 3.7 0.0022 18.1 1.5 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KKK15880.1 - 0.34 11.0 5.5 0.11 12.5 0.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Menin PF05053.8 KKK15880.1 - 0.82 7.7 8.0 1 7.4 5.6 1.1 1 0 0 1 1 1 0 Menin Actin PF00022.14 KKK15881.1 - 3.4e-24 85.0 0.0 2.2e-22 79.0 0.0 2.5 2 1 0 2 2 2 2 Actin TT_ORF2 PF02957.10 KKK15881.1 - 0.2 12.3 11.2 0.18 12.5 0.3 2.9 2 0 0 2 2 2 0 TT viral ORF2 CBFD_NFYB_HMF PF00808.18 KKK15882.1 - 2.6e-17 62.6 0.2 2.6e-17 62.6 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK15882.1 - 4.6e-05 23.4 0.0 6.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KKK15882.1 - 0.008 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Mrr_N PF14338.1 KKK15882.1 - 0.11 12.5 0.8 0.18 11.9 0.2 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain YolD PF08863.5 KKK15882.1 - 1.6 8.6 4.1 3.2 7.6 2.9 1.5 1 0 0 1 1 1 0 YolD-like protein adh_short PF00106.20 KKK15883.1 - 1.9e-28 99.4 0.5 2.8e-28 98.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK15883.1 - 6e-12 45.8 0.0 8.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK15883.1 - 4.1e-10 39.6 0.3 8.3e-10 38.6 0.2 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK15883.1 - 9.2e-05 22.5 0.1 0.00014 21.8 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK15883.1 - 0.0013 18.1 0.0 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KKK15883.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.8 KKK15883.1 - 0.029 13.6 0.2 0.053 12.7 0.1 1.4 2 0 0 2 2 2 0 NmrA-like family Shikimate_DH PF01488.15 KKK15883.1 - 0.05 13.6 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KKK15883.1 - 0.09 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 KKK15883.1 - 0.11 12.3 0.2 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DAO PF01266.19 KKK15884.1 - 1.4e-27 96.5 0.3 5.3e-27 94.6 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK15884.1 - 0.028 14.4 0.0 0.079 13.0 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SMC_Nse1 PF07574.8 KKK15885.1 - 2.7e-35 121.8 0.0 4.6e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KKK15885.1 - 2.1e-09 37.2 10.2 5.4e-09 35.9 7.1 1.8 1 0 0 1 1 1 1 RING-like domain zf-CCCH PF00642.19 KKK15885.1 - 1.7e-07 30.7 17.3 9.4e-07 28.3 1.5 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KKK15885.1 - 4.5e-05 23.2 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK15885.1 - 0.0022 17.6 0.0 0.0059 16.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 KKK15885.1 - 0.093 12.5 7.3 0.27 11.0 5.1 1.8 1 0 0 1 1 1 0 Ring finger domain hEGF PF12661.2 KKK15891.1 - 0.0037 17.2 1.8 0.0083 16.1 1.3 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF DUF997 PF06196.7 KKK15891.1 - 0.095 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DUF2207 PF09972.4 KKK15891.1 - 0.22 10.0 0.0 0.38 9.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2749 PF10907.3 KKK15891.1 - 0.5 10.2 1.9 2 8.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) ATP-sulfurylase PF01747.12 KKK15892.1 - 9.9e-86 286.4 0.1 1.5e-85 285.9 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KKK15892.1 - 1.2e-59 200.4 0.0 2e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KKK15892.1 - 1.9e-50 170.3 0.0 3.2e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 KKK15892.1 - 0.018 14.9 0.5 0.089 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 KKK15892.1 - 0.033 13.3 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Complex1_LYR_1 PF13232.1 KKK15893.1 - 6.1e-16 58.3 5.4 6.1e-16 58.3 3.7 2.0 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 KKK15893.1 - 1.3e-14 53.7 4.7 1.3e-14 53.7 3.3 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Kei1 PF08552.6 KKK15894.1 - 0.053 13.1 1.6 0.082 12.5 1.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 HLH PF00010.21 KKK15895.1 - 2.5e-16 59.1 1.6 4.8e-16 58.1 0.6 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Glyco_hydro_16 PF00722.16 KKK15922.1 - 2e-43 147.8 1.9 2e-43 147.8 1.3 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Hira PF07569.6 KKK15922.1 - 0.2 10.8 4.0 0.33 10.1 2.8 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split tRNA-synt_2b PF00587.20 KKK15923.1 - 8.1e-48 162.2 0.0 1.5e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Fungal_trans PF04082.13 KKK15923.1 - 8e-28 97.0 1.5 1.4e-27 96.2 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HGTP_anticodon PF03129.15 KKK15923.1 - 5.6e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain DUF3439 PF11921.3 KKK15923.1 - 2 8.2 6.6 5.1 6.8 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sugar_tr PF00083.19 KKK15924.1 - 1.1e-68 231.9 14.4 4e-65 220.1 6.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK15924.1 - 5.3e-19 68.1 17.0 5.3e-19 68.1 11.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Cyt-b5 PF00173.23 KKK15925.1 - 5.2e-10 38.9 0.0 7.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NQR2_RnfD_RnfE PF03116.10 KKK15925.1 - 0.083 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family His_Phos_2 PF00328.17 KKK15926.1 - 1.2e-18 67.6 0.0 2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Gtr1_RagA PF04670.7 KKK15927.1 - 8.6e-71 237.7 0.2 3e-70 235.9 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KKK15927.1 - 0.00014 21.1 0.0 0.00032 19.9 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KKK15927.1 - 0.0025 18.2 0.0 0.0081 16.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KKK15927.1 - 0.037 13.2 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KKK15927.1 - 0.076 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain FA_hydroxylase PF04116.8 KKK15928.1 - 7e-16 58.6 15.1 7e-16 58.6 10.5 2.4 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Lactamase_B_2 PF12706.2 KKK15929.1 - 3.4e-27 95.2 0.1 8.4e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KKK15929.1 - 5.7e-22 76.9 0.0 1.7e-21 75.4 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease bZIP_1 PF00170.16 KKK15929.1 - 1.7e-08 34.2 10.7 4.2e-08 33.0 7.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor Lactamase_B PF00753.22 KKK15929.1 - 3.5e-07 30.0 0.0 9.3e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily bZIP_2 PF07716.10 KKK15929.1 - 4.3e-05 23.2 10.0 4.3e-05 23.2 6.9 2.9 2 0 0 2 2 2 1 Basic region leucine zipper AIG2 PF06094.7 KKK15930.1 - 3e-11 43.6 0.0 5.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family ABC_tran PF00005.22 KKK15931.1 - 2.6e-40 137.9 5.1 3.3e-20 72.7 0.0 3.8 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KKK15931.1 - 2e-17 64.0 0.5 7.3e-08 32.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KKK15931.1 - 1.4e-09 37.5 3.7 0.015 14.4 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 KKK15931.1 - 7.4e-09 35.3 2.1 7.4e-09 35.3 1.4 2.3 2 0 0 2 2 1 1 ABC transporter AAA_17 PF13207.1 KKK15931.1 - 2.2e-07 31.7 0.2 0.016 15.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KKK15931.1 - 1.8e-06 27.3 0.3 0.003 17.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK15931.1 - 1.3e-05 25.2 0.5 0.21 11.7 0.0 3.9 3 2 0 3 3 3 1 AAA domain Miro PF08477.8 KKK15931.1 - 4.9e-05 23.8 0.0 0.53 10.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 KKK15931.1 - 0.00015 22.0 0.1 0.43 10.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KKK15931.1 - 0.00019 21.3 0.1 0.12 12.3 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KKK15931.1 - 0.00046 20.1 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KKK15931.1 - 0.00055 20.1 0.0 0.81 9.8 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KKK15931.1 - 0.00084 18.5 0.2 1.5 7.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ArgK PF03308.11 KKK15931.1 - 0.00089 18.1 0.6 0.23 10.2 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_5 PF07728.9 KKK15931.1 - 0.0013 18.4 0.9 0.31 10.7 0.0 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 KKK15931.1 - 0.0017 16.9 10.1 0.015 13.7 0.4 2.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KKK15931.1 - 0.0018 18.2 2.5 1.1 9.2 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KKK15931.1 - 0.0021 17.9 0.2 1.8 8.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 KKK15931.1 - 0.0029 17.7 0.1 0.93 9.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KKK15931.1 - 0.0031 16.9 0.0 0.63 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KKK15931.1 - 0.0038 17.0 0.2 3 7.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KKK15931.1 - 0.004 16.8 0.2 0.87 9.2 0.0 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KKK15931.1 - 0.005 17.1 13.0 1 9.6 7.5 3.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KKK15931.1 - 0.0089 15.6 0.2 0.48 10.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 KKK15931.1 - 0.019 14.6 0.9 14 5.3 0.0 3.8 4 0 0 4 4 3 0 NTPase AAA_10 PF12846.2 KKK15931.1 - 0.039 13.4 0.0 7 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 KKK15931.1 - 0.051 13.4 2.3 3.8 7.5 0.0 3.7 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 KKK15931.1 - 0.12 11.8 0.6 13 5.3 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 KKK15931.1 - 0.34 10.4 1.8 14 5.0 0.1 3.2 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 KKK15931.1 - 1.6 8.5 5.4 2.6 7.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 TrkH PF02386.11 KKK15932.1 - 5.4e-66 222.5 7.5 5.4e-66 222.5 5.2 2.6 2 1 0 2 2 2 1 Cation transport protein MoaC PF01967.16 KKK15933.1 - 1e-46 157.9 0.1 1.7e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KKK15933.1 - 3.4e-36 123.7 0.0 2.5e-35 120.9 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KKK15933.1 - 2e-20 73.6 0.0 3.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KKK15933.1 - 0.0001 22.4 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KKK15933.1 - 0.00012 22.1 0.0 0.0015 18.5 0.0 2.4 2 0 0 2 2 2 1 4Fe-4S single cluster domain Cast PF10174.4 KKK15934.1 - 0.019 13.0 0.2 0.038 12.0 0.1 1.4 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Phage_GPO PF05929.6 KKK15934.1 - 0.02 14.1 1.4 0.032 13.4 0.5 1.7 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Baculo_PEP_C PF04513.7 KKK15934.1 - 0.046 13.5 0.4 9.2 6.0 0.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_15 PF09445.5 KKK15934.1 - 0.11 12.0 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Fez1 PF06818.10 KKK15934.1 - 0.16 12.0 1.2 0.33 10.9 0.9 1.5 1 0 0 1 1 1 0 Fez1 Syntaxin-6_N PF09177.6 KKK15934.1 - 0.39 11.1 2.9 2.4 8.5 0.2 2.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 KKK15934.1 - 0.45 10.8 3.1 3.2 8.0 0.4 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Adeno_PIX PF03955.9 KKK15934.1 - 5.1 7.6 7.6 0.92 10.0 0.2 3.0 4 0 0 4 4 4 0 Adenovirus hexon-associated protein (IX) Gyro_capsid PF04162.7 KKK15935.1 - 0.079 11.1 0.0 0.079 11.1 0.0 1.0 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Shadoo PF14999.1 KKK15935.1 - 0.71 9.7 8.4 0.72 9.7 5.8 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective ICAP-1_inte_bdg PF10480.4 KKK15935.1 - 1.4 8.6 4.4 1.6 8.4 3.0 1.0 1 0 0 1 1 1 0 Beta-1 integrin binding protein ADH_N PF08240.7 KKK15936.1 - 1e-27 96.0 1.1 2.1e-27 95.0 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK15936.1 - 3.5e-12 46.0 0.0 8.5e-12 44.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 KKK15936.1 - 0.041 13.6 0.0 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 S1-like Pyr_redox_3 PF13738.1 KKK15936.1 - 0.14 12.1 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.24 KKK15937.1 - 2.1e-26 92.3 0.0 5.5e-25 87.8 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK15937.1 - 3.2e-23 81.3 0.0 2.4e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK15937.1 - 3.7e-06 26.8 0.0 7.7e-05 22.5 0.0 2.5 1 1 2 3 3 3 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KKK15937.1 - 0.0043 15.5 0.5 0.32 9.3 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) ATP-synt_G PF04718.10 KKK15938.1 - 1e-32 112.8 0.1 1.1e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Methyltransf_16 PF10294.4 KKK15939.1 - 3e-21 75.6 0.0 6e-21 74.6 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KKK15939.1 - 0.049 14.2 0.0 0.12 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KKK15939.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain VPS28 PF03997.7 KKK15941.1 - 5.4e-61 205.4 0.0 6.5e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Imm3 PF14425.1 KKK15941.1 - 0.12 12.2 0.7 0.99 9.3 0.1 2.3 2 0 0 2 2 2 0 Immunity protein Imm3 Glyco_hydro_31 PF01055.21 KKK15942.1 - 1.7e-171 570.9 1.2 2.1e-171 570.6 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KKK15942.1 - 4.7e-11 42.3 2.1 1.5e-10 40.7 1.5 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Amidohydro_2 PF04909.9 KKK15943.1 - 5.6e-25 88.4 0.0 7e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Noc2 PF03715.8 KKK15944.1 - 8e-109 363.1 0.3 1.5e-105 352.3 0.2 2.7 1 1 0 1 1 1 1 Noc2p family PPP4R2 PF09184.6 KKK15944.1 - 0.0087 15.6 17.7 0.0087 15.6 12.2 3.4 2 1 0 2 2 2 1 PPP4R2 adh_short PF00106.20 KKK15944.1 - 0.095 12.6 1.8 0.45 10.4 0.0 2.4 2 0 0 2 2 2 0 short chain dehydrogenase tRNA-synt_2b PF00587.20 KKK15969.1 - 5.2e-33 114.0 0.0 7.6e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KKK15969.1 - 1.3e-16 60.5 5.2 1.3e-16 60.5 3.6 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 KKK15969.1 - 0.15 11.7 5.1 0.038 13.6 0.7 1.9 2 0 0 2 2 2 0 Mnd1 family DUF4375 PF14300.1 KKK15969.1 - 0.23 11.4 2.5 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Ras PF00071.17 KKK15970.1 - 1.5e-38 131.7 0.6 1.9e-37 128.1 0.4 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK15970.1 - 2.7e-11 43.9 0.4 1.5e-10 41.6 0.2 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK15970.1 - 3.6e-06 26.9 0.0 4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KKK15970.1 - 2.6e-05 23.5 0.0 0.0014 17.8 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KKK15970.1 - 0.0017 17.5 0.0 0.0058 15.8 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KKK15970.1 - 0.0087 15.9 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KKK15970.1 - 0.0091 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KKK15970.1 - 0.06 12.6 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.1 KKK15970.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ACT PF01842.20 KKK15971.1 - 3.8e-05 23.0 0.0 4.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 ACT domain FliG_M PF14841.1 KKK15971.1 - 0.082 12.9 0.0 0.38 10.7 0.0 1.8 1 1 1 2 2 2 0 FliG middle domain 2-Hacid_dh_C PF02826.14 KKK15972.1 - 7e-52 175.1 0.0 9.9e-52 174.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK15972.1 - 3.4e-34 117.1 0.0 4.1e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KKK15972.1 - 5.4e-06 26.3 0.1 1.5e-05 24.8 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KKK15972.1 - 0.0005 19.9 0.0 0.0015 18.3 0.0 1.8 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KKK15972.1 - 0.011 15.1 0.1 0.35 10.2 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 KKK15972.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 KKK15972.1 - 0.088 12.4 0.2 0.77 9.3 0.2 2.0 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S3Ae PF01015.13 KKK15973.1 - 8.5e-80 266.6 5.8 1e-79 266.3 4.0 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 KKK15973.1 - 0.1 12.8 0.6 0.37 10.9 0.0 2.2 2 1 0 2 2 2 0 Syntaxin WAPL PF07814.8 KKK15974.1 - 2.6e-49 167.8 0.0 1.3e-48 165.6 0.0 1.9 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin RNA_pol_I_A49 PF06870.7 KKK15974.1 - 0.039 12.5 0.0 0.057 11.9 0.0 1.2 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor UPRTase PF14681.1 KKK15975.1 - 9.8e-68 227.4 0.0 1.1e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KKK15975.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KKK15975.1 - 0.095 12.4 0.5 0.16 11.6 0.3 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Pkinase PF00069.20 KKK15976.1 - 5.1e-62 209.3 0.0 6.1e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15976.1 - 1e-24 87.0 0.0 1.3e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase E1-E2_ATPase PF00122.15 KKK15977.1 - 4.8e-31 107.5 0.9 8e-31 106.8 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KKK15977.1 - 1.6e-27 96.9 0.0 1.3e-26 93.9 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK15977.1 - 1.8e-15 57.9 0.0 1.3e-14 55.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KKK15977.1 - 5.7e-08 32.5 5.4 5.7e-08 32.5 3.7 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 KKK15977.1 - 0.00035 19.9 0.3 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus P5-ATPase PF12409.3 KKK15977.1 - 0.031 14.1 0.4 0.086 12.7 0.0 2.0 2 0 0 2 2 2 0 P5-type ATPase cation transporter Hydrolase_3 PF08282.7 KKK15977.1 - 0.093 12.2 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase VirK PF06903.7 KKK15977.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 VirK protein Zn_clus PF00172.13 KKK15978.1 - 1.1e-08 34.7 12.5 2e-08 33.9 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 KKK15978.1 - 0.0091 15.7 1.8 0.0091 15.7 1.2 2.1 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat FlxA PF14282.1 KKK15978.1 - 0.024 14.5 4.4 0.054 13.4 3.1 1.6 1 0 0 1 1 1 0 FlxA-like protein ELO PF01151.13 KKK15979.1 - 4.2e-60 203.1 19.7 5.3e-60 202.8 13.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COesterase PF00135.23 KKK15980.1 - 1.2e-89 301.5 0.0 2.1e-89 300.6 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK15980.1 - 1.7e-11 44.0 0.4 4.4e-11 42.7 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK15980.1 - 0.0012 18.6 0.2 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK15980.1 - 0.0035 16.5 0.2 0.0061 15.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Clr5 PF14420.1 KKK15981.1 - 1.3e-11 44.2 0.9 2.1e-11 43.5 0.6 1.3 1 0 0 1 1 1 1 Clr5 domain p450 PF00067.17 KKK15983.1 - 2.1e-58 198.0 0.0 2.6e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAGAT PF03982.8 KKK15984.1 - 2.8e-49 167.4 0.1 4.3e-49 166.8 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase UDPGT PF00201.13 KKK15984.1 - 9.9e-10 37.5 0.0 1.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KKK15984.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KKK15984.1 - 0.029 13.5 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 1 RVT_1 PF00078.22 KKK15985.1 - 2.3e-06 27.1 0.0 5.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_membrane PF00664.18 KKK15986.1 - 9.6e-82 274.4 34.0 2.5e-43 148.4 10.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KKK15986.1 - 9.2e-72 239.7 0.0 7.5e-36 123.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KKK15986.1 - 4.6e-14 52.1 0.0 6e-05 22.3 0.0 3.9 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK15986.1 - 8.8e-13 48.8 1.4 0.034 14.1 0.0 4.3 3 1 1 4 4 4 4 AAA domain ABC_ATPase PF09818.4 KKK15986.1 - 2.5e-10 39.5 3.9 4.4e-05 22.2 0.2 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KKK15986.1 - 9.4e-09 35.5 0.3 0.0067 16.4 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KKK15986.1 - 2.6e-08 33.2 0.3 0.0004 19.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KKK15986.1 - 1.6e-07 32.1 0.0 0.032 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KKK15986.1 - 5e-07 29.0 0.1 0.015 14.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KKK15986.1 - 9.1e-06 25.2 3.9 0.18 11.2 0.0 4.8 6 0 0 6 6 6 2 AAA domain SbcCD_C PF13558.1 KKK15986.1 - 9.1e-06 25.5 3.7 0.085 12.7 0.2 4.2 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KKK15986.1 - 1.5e-05 25.1 1.9 0.48 10.5 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KKK15986.1 - 9.7e-05 22.6 0.0 0.35 11.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KKK15986.1 - 0.00013 21.8 0.0 0.48 10.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.17 KKK15986.1 - 0.00042 19.8 0.0 1.3 8.4 0.0 2.9 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KKK15986.1 - 0.00071 19.5 0.1 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KKK15986.1 - 0.0018 17.9 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KKK15986.1 - 0.0021 18.4 1.2 0.25 11.6 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KKK15986.1 - 0.0059 16.3 0.1 8.2 6.1 0.0 3.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KKK15986.1 - 0.0065 15.9 4.0 2.1 7.6 0.2 4.3 5 0 0 5 5 4 1 AAA-like domain AAA_30 PF13604.1 KKK15986.1 - 0.0078 15.8 7.0 2 7.9 0.1 4.4 4 1 0 4 4 4 1 AAA domain DUF87 PF01935.12 KKK15986.1 - 0.014 15.2 0.4 3.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KKK15986.1 - 0.022 14.7 0.0 12 5.8 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 KKK15986.1 - 0.052 12.7 0.0 2.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KKK15986.1 - 0.057 13.5 0.1 10 6.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase PRK PF00485.13 KKK15986.1 - 0.071 12.6 0.0 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 KKK15986.1 - 0.075 12.6 0.0 4.8 6.8 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Katanin_con80 PF13925.1 KKK15986.1 - 0.081 12.6 0.0 22 4.7 0.0 3.3 3 0 0 3 3 3 0 con80 domain of Katanin G-alpha PF00503.15 KKK15986.1 - 0.086 11.5 0.0 5.4 5.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_15 PF13175.1 KKK15986.1 - 0.089 11.8 0.0 9.1 5.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.10 KKK15986.1 - 0.15 10.7 0.0 1.6 7.3 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Tyrosinase PF00264.15 KKK15987.1 - 4.1e-30 105.6 9.9 5.5e-30 105.1 6.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_7 PF00840.15 KKK15988.1 - 7.7e-115 383.6 21.0 7.7e-75 251.8 9.8 2.9 2 1 1 3 3 3 2 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KKK15988.1 - 1.7e-14 53.1 10.6 1.7e-14 53.1 7.3 3.3 4 0 0 4 4 4 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KKK15988.1 - 4.1 7.5 10.8 0.068 13.2 1.8 2.3 3 0 0 3 3 3 0 Toxin 7 ATP-grasp_4 PF13535.1 KKK15990.1 - 2.5e-09 37.1 0.0 4.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KKK15990.1 - 3.4e-09 36.7 0.0 1e-08 35.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KKK15990.1 - 6.4e-09 35.0 0.0 4.8e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Glyco_hydro_16 PF00722.16 KKK15992.1 - 9.3e-10 38.0 0.1 2.4e-09 36.7 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 NIP_1 PF08995.5 KKK15992.1 - 0.028 14.5 0.8 0.065 13.4 0.5 1.6 1 0 0 1 1 1 0 Necrosis inducing protein-1 DPPIV_N PF00930.16 KKK15993.1 - 2.7e-17 62.3 0.5 8.4e-16 57.4 0.4 2.0 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DPPIV_N PF00930.16 KKK15994.1 - 2.4e-06 26.3 0.1 5.5e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_3 PF07859.8 KKK15995.1 - 6.6e-24 84.6 0.0 8.9e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK15995.1 - 1.1e-18 67.0 0.0 1.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK15995.1 - 1.1e-05 25.1 0.1 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK15995.1 - 0.00094 18.4 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Pro-kuma_activ PF09286.6 KKK15996.1 - 7e-42 142.8 0.0 1.4e-41 141.8 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KKK15996.1 - 2e-05 23.8 0.1 5.3e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 Subtilase family DUF1798 PF08807.5 KKK15996.1 - 0.11 12.1 0.3 0.23 11.1 0.2 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Ribosomal_S20p PF01649.13 KKK15996.1 - 0.15 12.5 3.0 0.24 11.7 2.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 AMP-binding PF00501.23 KKK16009.1 - 2.5e-71 240.2 0.0 3.3e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK16009.1 - 1e-16 61.6 0.1 2.4e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 KKK16010.1 - 1.2e-61 208.6 0.0 1.5e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK16010.1 - 2.2e-05 23.7 0.0 4.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KKK16010.1 - 0.027 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Ribosomal_L13 PF00572.13 KKK16011.1 - 1.4e-27 96.2 0.0 2.7e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 DnaJ PF00226.26 KKK16012.1 - 1.8e-23 82.0 1.0 4.2e-23 80.8 0.7 1.7 1 0 0 1 1 1 1 DnaJ domain Endonuc_Holl PF10107.4 KKK16012.1 - 6.6 6.4 9.1 0.46 10.1 0.1 2.5 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Kinesin PF00225.18 KKK16013.1 - 3.4e-113 377.7 0.0 3.4e-113 377.7 0.0 2.0 3 0 0 3 3 3 1 Kinesin motor domain Bacillus_HBL PF05791.6 KKK16013.1 - 0.029 13.7 0.3 0.029 13.7 0.2 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IF-2B PF01008.12 KKK16014.1 - 4.2e-75 252.3 0.0 5.2e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1275 PF06912.6 KKK16015.1 - 5.4e-47 159.6 10.4 6.7e-47 159.3 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Herpes_US9 PF06072.6 KKK16015.1 - 0.2 11.5 2.1 4.9 7.0 0.1 3.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Pol_alpha_B_N PF08418.5 KKK16017.1 - 3e-54 184.2 0.0 4.5e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KKK16017.1 - 1.2e-37 129.1 0.0 1.8e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B zf-H2C2_2 PF13465.1 KKK16022.1 - 8.7e-09 35.2 11.7 9.7e-07 28.7 1.9 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KKK16022.1 - 3.8e-08 33.2 12.9 1e-05 25.5 1.2 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK16022.1 - 2.2e-06 27.6 8.1 5e-05 23.3 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KKK16022.1 - 0.00082 19.4 7.9 0.028 14.6 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KKK16022.1 - 0.0014 18.7 3.4 0.02 15.0 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KKK16022.1 - 0.04 13.6 0.4 0.04 13.6 0.3 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 KKK16022.1 - 0.051 13.4 3.8 2.2 8.3 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger CrtC PF07143.6 KKK16023.1 - 1.5e-09 37.6 0.1 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) DLH PF01738.13 KKK16024.1 - 6.2e-09 35.4 0.0 1.3e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK16024.1 - 0.00025 20.7 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Tubulin PF00091.20 KKK16025.1 - 9.5e-67 224.9 0.0 1.3e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KKK16025.1 - 9.6e-45 151.6 0.0 1.5e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KKK16025.1 - 0.00044 19.7 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Vps8 PF12816.2 KKK16026.1 - 2.9e-70 235.5 0.0 5.9e-70 234.5 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Glyco_hydro_16 PF00722.16 KKK16026.1 - 2.3e-10 40.0 0.0 5.7e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Clathrin PF00637.15 KKK16026.1 - 1.1e-05 25.0 0.0 0.27 10.8 0.0 3.1 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KKK16026.1 - 0.00021 21.0 1.1 0.00059 19.6 0.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KKK16026.1 - 0.011 15.7 0.7 0.032 14.2 0.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Adeno_shaft PF00608.12 KKK16026.1 - 0.073 12.6 0.2 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Pox_D3 PF04580.8 KKK16026.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-RING_5 PF14634.1 KKK16026.1 - 1 9.1 4.5 0.15 11.7 0.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain DEAD PF00270.24 KKK16027.1 - 1.9e-17 63.2 0.0 4.5e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK16027.1 - 6.3e-10 38.7 0.0 1.6e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK16027.1 - 6.9e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_45 PF14947.1 KKK16027.1 - 6.5e-05 22.6 0.1 0.00029 20.5 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix AAA_22 PF13401.1 KKK16027.1 - 0.0029 17.7 0.3 0.024 14.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain HHH_5 PF14520.1 KKK16027.1 - 0.0049 17.0 0.0 0.019 15.1 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.1 KKK16027.1 - 0.077 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DUF336 PF03928.9 KKK16027.1 - 0.12 12.2 0.1 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF336) Glyco_transf_90 PF05686.7 KKK16028.1 - 2.3e-13 49.6 0.2 5.1e-07 28.7 0.1 3.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 Tetraspannin PF00335.15 KKK16028.1 - 0.032 13.5 0.3 0.064 12.5 0.2 1.5 1 0 0 1 1 1 0 Tetraspanin family Oxidored_FMN PF00724.15 KKK16043.1 - 8.4e-96 320.9 0.0 9.6e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.20 KKK16045.1 - 2.1e-58 197.5 0.3 4e-58 196.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16045.1 - 1e-36 126.3 0.0 2.9e-25 88.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KKK16045.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KKK16045.1 - 0.037 13.7 1.4 0.11 12.2 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF607 PF04678.8 KKK16045.1 - 0.069 13.0 1.3 0.13 12.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Effector_1 PF04518.7 KKK16045.1 - 0.11 11.4 1.1 0.18 10.7 0.7 1.2 1 0 0 1 1 1 0 Effector from type III secretion system DUF677 PF05055.7 KKK16045.1 - 0.15 10.6 8.5 0.24 10.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) APG6 PF04111.7 KKK16045.1 - 5.6 5.9 9.7 9.7 5.1 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 BTB PF00651.26 KKK16046.1 - 3.4e-26 91.4 0.0 1.8e-14 53.6 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 KKK16046.1 - 0.014 15.9 0.0 0.09 13.3 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 KKK16046.1 - 0.035 14.4 0.0 0.097 13.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Wbp11 PF09429.5 KKK16047.1 - 1.7e-22 79.1 14.0 1.7e-22 79.1 9.7 2.7 3 1 1 4 4 4 1 WW domain binding protein 11 DUF3038 PF11237.3 KKK16047.1 - 0.014 15.2 2.2 0.024 14.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DUF4332 PF14229.1 KKK16047.1 - 0.15 12.0 2.5 0.21 11.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Fungal_trans PF04082.13 KKK16048.1 - 2.4e-18 65.9 1.4 3.7e-18 65.3 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16048.1 - 6.1e-09 35.6 10.8 1.2e-08 34.6 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_5 PF13854.1 KKK16049.1 - 8.7e-19 67.0 4.0 1.2e-16 60.1 1.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 KKK16049.1 - 2e-06 27.7 3.8 0.02 15.0 0.3 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 KKK16049.1 - 6.5e-06 25.5 0.7 0.019 14.5 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 KKK16049.1 - 6.6e-06 26.1 4.5 0.052 13.7 0.0 5.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_4 PF13418.1 KKK16049.1 - 4.1e-05 23.2 6.6 0.061 13.1 0.1 5.3 5 1 0 5 5 5 1 Galactose oxidase, central domain MLANA PF14991.1 KKK16049.1 - 0.036 14.0 0.0 0.094 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A FAD_binding_3 PF01494.14 KKK16050.1 - 1.1e-15 57.5 0.5 1.8e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KKK16050.1 - 3.1e-09 36.7 0.8 7.6e-09 35.4 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK16050.1 - 3.1e-07 29.6 2.9 3.1e-07 29.6 2.0 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KKK16050.1 - 5.6e-06 25.7 0.0 7.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK16050.1 - 1.1e-05 25.4 0.2 2.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK16050.1 - 4.6e-05 22.4 0.0 6.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KKK16050.1 - 0.00012 21.2 0.1 0.0013 17.8 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KKK16050.1 - 0.00048 20.4 1.3 0.0014 18.9 0.9 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KKK16050.1 - 0.0036 16.2 0.8 0.0057 15.5 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KKK16050.1 - 0.0057 16.7 0.0 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK16050.1 - 0.0098 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Rossmann-like PF10727.4 KKK16050.1 - 0.014 15.1 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain HI0933_like PF03486.9 KKK16050.1 - 0.019 13.4 1.2 0.03 12.8 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 KKK16050.1 - 0.032 13.9 0.4 0.056 13.1 0.3 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 KKK16050.1 - 0.033 12.8 1.0 0.25 9.9 0.6 2.0 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 KKK16050.1 - 0.047 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KKK16050.1 - 0.19 11.3 0.6 0.4 10.3 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KKK16050.1 - 0.25 11.1 0.9 0.78 9.4 0.5 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding BRO1 PF03097.13 KKK16052.1 - 3.5e-05 22.7 0.2 5.3e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 BRO1-like domain Glt_symporter PF03616.9 KKK16052.1 - 1.8 6.9 4.4 6.9 5.0 1.9 2.0 2 0 0 2 2 2 0 Sodium/glutamate symporter NDUFB10 PF10249.4 KKK16053.1 - 0.0025 17.9 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 TAFII55_N PF04658.8 KKK16054.1 - 3.9e-51 172.7 0.0 7.8e-51 171.7 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region Bromo_TP PF07524.8 KKK16055.1 - 2.4e-09 36.7 0.0 4.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated ECH PF00378.15 KKK16056.1 - 5.9e-22 77.9 0.0 6.6e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Glyco_transf_34 PF05637.7 KKK16058.1 - 2.2e-30 105.9 0.0 2.6e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family GPP34 PF05719.6 KKK16086.1 - 7e-43 147.0 0.2 8.5e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) CBS PF00571.23 KKK16087.1 - 3.9e-24 84.1 4.8 8.8e-07 28.6 0.1 5.3 5 0 0 5 5 5 5 CBS domain DUF2183 PF09949.4 KKK16089.1 - 1.2e-30 105.4 0.1 2.3e-30 104.4 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 KKK16089.1 - 0.0049 16.4 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) RTA1 PF04479.8 KKK16093.1 - 1.4e-42 145.7 5.4 1.4e-42 145.7 3.8 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF4239 PF14023.1 KKK16093.1 - 0.1 11.9 3.4 0.19 11.0 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Disulph_isomer PF06491.6 KKK16094.1 - 0.063 13.1 0.2 0.072 12.9 0.2 1.2 1 0 0 1 1 1 0 Disulphide isomerase FHA PF00498.21 KKK16095.1 - 8.7e-17 61.0 0.0 1.8e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain ERM PF00769.14 KKK16095.1 - 0.00011 21.7 8.7 0.00011 21.7 6.0 3.2 3 0 0 3 3 3 2 Ezrin/radixin/moesin family CENP-Q PF13094.1 KKK16095.1 - 0.0082 16.1 13.0 0.0082 16.1 9.0 3.3 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 KKK16095.1 - 9.1 6.6 18.9 0.4 11.0 3.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Romo1 PF10247.4 KKK16096.1 - 7.8e-29 99.6 13.0 1.1e-28 99.2 9.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 AFP PF02420.10 KKK16096.1 - 0.16 12.2 2.0 0.37 11.0 1.4 1.7 1 0 0 1 1 1 0 Insect antifreeze protein repeat Rpp20 PF12328.3 KKK16097.1 - 4.4e-54 182.0 3.6 5.7e-54 181.6 2.5 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KKK16097.1 - 3.5e-23 80.9 0.9 5.9e-23 80.2 0.6 1.4 1 0 0 1 1 1 1 Alba LRR_8 PF13855.1 KKK16098.1 - 1.2e-12 47.3 4.0 2.1e-08 33.7 1.3 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KKK16098.1 - 3e-12 45.8 5.5 3.6e-07 29.6 1.1 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KKK16098.1 - 1.8e-06 27.1 9.5 0.082 12.9 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KKK16098.1 - 0.00014 21.4 4.9 0.27 11.6 0.0 4.1 3 0 0 3 3 3 2 Leucine rich repeat APH PF01636.18 KKK16099.1 - 1.7e-19 70.4 0.0 2.3e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK16099.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KKK16099.1 - 0.054 12.8 0.0 0.47 9.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 KKK16099.1 - 0.081 12.0 0.0 0.32 10.1 0.0 1.8 1 1 1 2 2 2 0 Ecdysteroid kinase Fic PF02661.13 KKK16100.1 - 7.9e-11 42.5 0.3 1.7e-10 41.4 0.2 1.5 1 1 0 1 1 1 1 Fic/DOC family Transketolase_N PF00456.16 KKK16101.1 - 5.5e-152 505.3 0.0 7.6e-152 504.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KKK16101.1 - 4e-44 150.2 0.0 7e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KKK16101.1 - 2.9e-06 26.4 0.0 0.0002 20.4 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KKK16101.1 - 4.2e-05 22.4 0.2 8.3e-05 21.4 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 KKK16101.1 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Fungal_trans PF04082.13 KKK16103.1 - 5.5e-38 130.3 0.0 1e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16103.1 - 1.6e-08 34.2 14.9 2.8e-08 33.5 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_MT_bd PF06657.8 KKK16103.1 - 0.057 13.3 1.3 14 5.7 0.1 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Striatin PF08232.7 KKK16103.1 - 0.062 13.6 1.3 4.4 7.6 0.1 2.6 2 0 0 2 2 2 0 Striatin family DUF4635 PF15466.1 KKK16103.1 - 0.21 10.8 1.3 0.34 10.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) MMR_HSR1_C PF08438.5 KKK16104.1 - 3.9e-32 110.7 0.0 7.7e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KKK16104.1 - 3.2e-13 49.6 0.0 7.2e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK16104.1 - 0.00045 19.5 0.2 0.0061 15.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KKK16104.1 - 0.00074 19.3 1.3 0.32 10.8 0.4 2.9 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 KKK16104.1 - 0.0015 18.0 0.0 0.56 9.6 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KKK16104.1 - 0.042 14.1 0.0 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 KKK16104.1 - 0.043 14.1 0.1 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KKK16104.1 - 0.053 13.0 0.0 0.52 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KKK16104.1 - 0.06 12.1 0.1 0.2 10.3 0.0 1.8 2 0 0 2 2 2 0 ArgK protein AAA_33 PF13671.1 KKK16104.1 - 0.079 12.8 0.1 4.9 7.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain RHD3 PF05879.7 KKK16104.1 - 0.11 10.4 0.8 0.84 7.4 0.0 2.0 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) KTI12 PF08433.5 KKK16104.1 - 0.17 11.0 0.1 0.36 9.9 0.1 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.12 KKK16104.1 - 0.21 11.1 0.3 17 4.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L7Ae PF01248.21 KKK16108.1 - 3.3e-19 68.2 1.1 3e-18 65.1 0.8 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MAD PF05557.8 KKK16109.1 - 2.8e-53 181.1 77.6 2.9e-44 151.3 53.8 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein Aldo_ket_red PF00248.16 KKK16111.1 - 2.5e-45 154.4 0.0 3.2e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.9 KKK16112.1 - 1.8e-09 36.9 0.0 9.9e-09 34.5 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KKK16112.1 - 1.2e-07 31.1 0.0 1.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KKK16112.1 - 3.2e-07 30.3 0.1 0.0044 16.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KKK16112.1 - 6.1e-05 22.2 0.0 8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KKK16112.1 - 0.0043 16.4 0.0 0.068 12.5 0.0 2.5 2 1 0 2 2 2 1 RIO1 family Chitin_synth_1 PF01644.12 KKK16113.1 - 1.5e-68 229.6 0.0 3.5e-68 228.5 0.0 1.6 2 0 0 2 2 2 1 Chitin synthase UQ_con PF00179.21 KKK16113.1 - 2.1e-36 124.4 0.0 3.5e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1N PF08407.6 KKK16113.1 - 2.1e-27 94.5 0.1 4e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KKK16113.1 - 5.1e-25 87.8 0.0 2e-21 76.0 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KKK16113.1 - 8.6e-13 48.4 0.1 8.6e-13 48.4 0.0 2.6 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK16113.1 - 2.3e-09 37.3 0.0 6.4e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RNA_pol_Rpb1_5 PF04998.12 KKK16114.1 - 9.9e-91 303.8 1.4 1.8e-90 302.9 1.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KKK16114.1 - 5.2e-84 282.3 0.0 7.7e-84 281.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KKK16114.1 - 8e-67 224.3 0.0 2e-66 223.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KKK16114.1 - 1e-33 116.3 0.0 4.3e-33 114.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KKK16114.1 - 1.7e-27 95.3 0.1 4.6e-27 93.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 GTP_EFTU PF00009.22 KKK16115.1 - 1.2e-48 165.0 0.0 2.1e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KKK16115.1 - 8.6e-39 131.7 3.7 1.4e-38 131.1 2.6 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KKK16115.1 - 1.9e-19 69.2 0.0 3.9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 KKK16115.1 - 3.3e-05 23.3 0.0 0.00012 21.5 0.0 1.8 2 0 0 2 2 2 1 Ras family GTP_EFTU_D2 PF03144.20 KKK16115.1 - 3.9e-05 23.6 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KKK16115.1 - 6.2e-05 22.9 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 KKK16115.1 - 0.0064 16.3 0.0 0.02 14.7 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 KKK16115.1 - 0.04 13.1 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1836 PF08876.6 KKK16115.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) HORMA PF02301.13 KKK16116.1 - 7.7e-50 169.2 0.3 8.7e-50 169.0 0.2 1.0 1 0 0 1 1 1 1 HORMA domain SspB PF04386.8 KKK16116.1 - 0.53 9.8 5.3 0.82 9.2 0.0 2.6 2 1 1 3 3 3 0 Stringent starvation protein B zf-CCCH PF00642.19 KKK16117.1 - 0.0046 16.6 0.7 0.0076 15.9 0.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sec1 PF00995.18 KKK16118.1 - 3.3e-157 524.5 0.0 3.9e-157 524.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RNA_lig_T4_1 PF09511.5 KKK16118.1 - 0.033 13.6 0.3 0.053 12.9 0.2 1.3 1 0 0 1 1 1 0 RNA ligase STE2 PF02116.10 KKK16119.1 - 3.5e-99 331.4 13.4 4.1e-99 331.1 9.3 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PufQ PF05398.6 KKK16119.1 - 0.13 12.3 1.0 7.7 6.6 0.1 2.5 1 1 1 2 2 2 0 PufQ cytochrome subunit UEV PF05743.8 KKK16120.1 - 1.9e-39 134.0 0.1 3e-39 133.4 0.1 1.3 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.21 KKK16120.1 - 0.0026 17.2 0.1 0.0061 16.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme KLRAQ PF10205.4 KKK16120.1 - 0.04 13.9 0.3 0.074 13.0 0.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Striatin PF08232.7 KKK16120.1 - 0.076 13.3 1.2 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 Striatin family TMF_TATA_bd PF12325.3 KKK16120.1 - 0.087 12.5 1.3 0.15 11.8 0.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Sipho_Gp157 PF05565.6 KKK16120.1 - 0.15 11.6 0.1 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Spectrin PF00435.16 KKK16120.1 - 0.17 12.2 0.9 0.34 11.2 0.6 1.4 1 0 0 1 1 1 0 Spectrin repeat BAR PF03114.13 KKK16121.1 - 6.9e-66 222.0 6.0 8.7e-66 221.7 4.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KKK16121.1 - 5.6e-15 54.4 0.0 9.7e-15 53.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK16121.1 - 1.1e-10 40.9 0.0 1.8e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KKK16121.1 - 1.6e-08 33.8 0.0 3.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GldM_N PF12081.3 KKK16121.1 - 0.067 12.7 4.2 0.96 8.9 0.8 2.3 2 0 0 2 2 2 0 GldM N-terminal domain Vps5 PF09325.5 KKK16121.1 - 0.093 11.9 5.6 1.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Vps5 C terminal like Retinal PF15449.1 KKK16121.1 - 0.12 10.0 2.3 0.18 9.4 1.6 1.2 1 0 0 1 1 1 0 Retinal protein Tropomyosin PF00261.15 KKK16121.1 - 0.26 10.3 11.2 1.1 8.2 0.2 2.3 2 0 0 2 2 2 0 Tropomyosin APG6 PF04111.7 KKK16121.1 - 0.77 8.7 8.0 3.3 6.6 2.5 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Aminotran_5 PF00266.14 KKK16122.1 - 4.3e-42 144.1 0.0 5.5e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Opy2 PF09463.5 KKK16123.1 - 7.4e-11 41.9 23.2 1.2e-10 41.2 16.1 1.4 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 KKK16123.1 - 0.0018 17.8 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 KKK16123.1 - 0.022 14.0 0.4 0.05 12.9 0.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain P12 PF12669.2 KKK16123.1 - 0.34 11.1 0.1 0.34 11.1 0.1 2.7 2 1 0 2 2 2 0 Virus attachment protein p12 family Beta-APP PF03494.8 KKK16123.1 - 8.9 5.8 6.8 16 5.1 4.7 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Aldo_ket_red PF00248.16 KKK16124.1 - 1.1e-15 57.2 0.0 1.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.17 KKK16130.1 - 5.9e-06 25.8 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK16130.1 - 0.00049 19.8 0.0 0.00096 18.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK16130.1 - 0.0036 17.2 0.0 0.0086 16.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_28 PF02636.12 KKK16131.1 - 1.9e-79 266.6 0.0 2.6e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Protocadherin PF08374.6 KKK16131.1 - 0.095 12.3 0.3 0.23 11.0 0.3 1.5 2 0 0 2 2 2 0 Protocadherin tRNA_int_end_N2 PF12928.2 KKK16131.1 - 0.14 11.6 0.1 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term Zip PF02535.17 KKK16132.1 - 0.18 10.8 6.5 0.19 10.7 4.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 KKK16132.1 - 0.6 9.8 10.4 0.65 9.7 7.2 1.1 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.9 KKK16132.1 - 1.3 8.4 13.9 1.5 8.2 9.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.3 KKK16132.1 - 2.5 7.9 19.5 3.2 7.6 13.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MRVI1 PF05781.7 KKK16132.1 - 2.7 6.3 20.3 2.9 6.1 14.0 1.0 1 0 0 1 1 1 0 MRVI1 protein FLO_LFY PF01698.11 KKK16132.1 - 2.7 6.7 8.2 2.9 6.6 5.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 KKK16132.1 - 2.8 7.7 22.5 2.7 7.8 15.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 KKK16132.1 - 3 7.1 25.0 3.1 7.0 17.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Raftlin PF15250.1 KKK16132.1 - 3.1 6.2 9.3 3.1 6.1 6.5 1.0 1 0 0 1 1 1 0 Raftlin DHHW PF14286.1 KKK16132.1 - 3.2 6.9 11.4 3.3 6.9 7.9 1.0 1 0 0 1 1 1 0 DHHW protein CDC45 PF02724.9 KKK16132.1 - 3.3 5.6 16.7 3.2 5.6 11.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Hox9_act PF04617.8 KKK16132.1 - 3.4 7.7 10.6 3.8 7.6 7.3 1.1 1 0 0 1 1 1 0 Hox9 activation region PPP4R2 PF09184.6 KKK16132.1 - 5.5 6.4 26.9 6.8 6.1 18.6 1.1 1 0 0 1 1 1 0 PPP4R2 Spore_coat_CotO PF14153.1 KKK16132.1 - 8.6 5.7 25.8 9.7 5.5 17.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CobT PF06213.7 KKK16132.1 - 9.2 5.3 24.6 11 5.0 17.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 KKK16132.1 - 9.8 5.3 9.6 11 5.1 6.7 1.1 1 0 0 1 1 1 0 NOA36 protein Acyltransferase PF01553.16 KKK16133.1 - 1.3e-10 40.7 0.0 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Lipase_GDSL PF00657.17 KKK16134.1 - 2.5e-12 47.1 1.7 3.4e-12 46.7 1.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PhrC_PhrF PF11131.3 KKK16134.1 - 0.0087 15.6 0.3 0.018 14.6 0.2 1.5 1 0 0 1 1 1 1 Rap-phr extracellular signalling Cellulase PF00150.13 KKK16135.1 - 2.7e-55 187.5 0.6 3.5e-55 187.1 0.4 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) XPG_N PF00752.12 KKK16136.1 - 1.8e-36 124.4 0.1 5.6e-36 122.8 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KKK16136.1 - 1.1e-24 86.3 0.0 3.1e-24 84.8 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 KKK16136.1 - 1.9e-05 23.8 0.4 1.9e-05 23.8 0.2 3.6 4 0 0 4 4 4 2 Ubiquitin interaction motif 5_3_exonuc PF01367.15 KKK16136.1 - 0.0012 19.0 0.0 0.0042 17.2 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 KKK16136.1 - 0.0067 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing Transposase_20 PF02371.11 KKK16136.1 - 0.058 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family WD40 PF00400.27 KKK16137.1 - 1.7e-26 91.0 19.7 2.3e-08 33.6 0.6 10.7 9 1 0 9 9 9 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KKK16137.1 - 0.0056 15.4 2.9 0.41 9.3 0.0 3.6 2 1 1 3 3 3 2 Nup133 N terminal like Pil1 PF13805.1 KKK16138.1 - 6.8e-152 504.2 0.6 8.4e-152 503.9 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 HAD_2 PF13419.1 KKK16138.1 - 0.052 13.7 0.1 0.09 12.9 0.1 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FAM92 PF06730.6 KKK16138.1 - 0.063 12.6 4.0 0.047 13.0 1.6 1.6 2 0 0 2 2 2 0 FAM92 protein V_ATPase_I PF01496.14 KKK16138.1 - 0.16 9.7 1.2 0.23 9.2 0.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dioxygenase_C PF00775.16 KKK16139.1 - 0.09 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Dioxygenase CASP_C PF08172.7 KKK16140.1 - 4.5e-90 301.0 3.9 4.5e-90 301.0 2.7 4.1 3 1 2 5 5 5 1 CASP C terminal MotB_plug PF13677.1 KKK16140.1 - 0.04 13.2 0.5 0.12 11.7 0.4 1.7 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB UPF0184 PF03670.8 KKK16140.1 - 0.34 11.1 11.9 0.97 9.6 0.3 4.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) DUF3584 PF12128.3 KKK16140.1 - 0.69 7.1 44.6 0.012 13.0 16.8 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) Vps39_2 PF10367.4 KKK16141.1 - 7.8e-05 22.8 0.0 0.00029 20.9 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KKK16141.1 - 0.051 13.5 0.1 0.64 10.0 0.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Fibrillarin PF01269.12 KKK16142.1 - 9.9e-107 355.0 0.0 1.2e-106 354.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KKK16142.1 - 2.9e-06 26.9 0.1 5.4e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KKK16142.1 - 0.045 13.2 0.1 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KKK16142.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3455 PF11937.3 KKK16143.1 - 1.4e-49 168.4 0.1 1.7e-49 168.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 KKK16143.1 - 1.8e-26 91.7 2.3 4.3e-26 90.5 1.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Peptidase_M16 PF00675.15 KKK16144.1 - 2.8e-57 192.6 0.1 1.4e-56 190.4 0.2 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KKK16144.1 - 7e-42 143.1 0.0 5.6e-40 136.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Epimerase PF01370.16 KKK16144.1 - 8.7e-22 77.7 0.0 1.6e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK16144.1 - 2.8e-10 39.3 0.0 4.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KKK16144.1 - 9.7e-08 32.2 0.0 5.4e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KKK16144.1 - 1.2e-06 28.5 0.6 4.7e-06 26.6 0.1 2.2 3 0 0 3 3 3 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KKK16144.1 - 0.00011 21.2 0.0 0.00021 20.2 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KKK16144.1 - 0.0006 18.8 0.0 0.014 14.3 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KKK16144.1 - 0.018 15.3 0.0 0.099 12.9 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KKK16144.1 - 0.025 14.3 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KKK16144.1 - 0.029 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 KKK16144.1 - 0.037 13.6 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 KR domain INO80_Ies4 PF08193.6 KKK16150.1 - 9.7e-86 287.3 23.2 4.3e-85 285.1 16.1 1.8 1 1 0 1 1 1 1 INO80 complex subunit Ies4 Arginase PF00491.16 KKK16153.1 - 1.4e-76 257.4 0.2 1.6e-76 257.2 0.2 1.0 1 0 0 1 1 1 1 Arginase family Glyco_hydro_47 PF01532.15 KKK16160.1 - 6.4e-140 466.7 0.0 8.2e-140 466.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 KKK16160.1 - 0.13 12.5 0.1 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Ank_2 PF12796.2 KKK16161.1 - 3.4e-50 168.3 6.7 1.5e-16 60.5 0.5 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KKK16161.1 - 4.8e-48 158.6 15.4 2e-09 36.7 0.2 9.6 9 1 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 KKK16161.1 - 5.1e-39 131.9 9.5 3.1e-10 40.2 0.3 7.1 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK16161.1 - 1.4e-33 111.5 8.8 0.00015 21.6 0.1 9.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KKK16161.1 - 1.8e-33 113.7 15.8 4.3e-08 33.1 0.2 7.6 4 3 2 7 7 7 6 Ankyrin repeats (many copies) CorA PF01544.13 KKK16161.1 - 1.9e-11 43.5 0.5 6.6e-11 41.7 0.3 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PRP1_N PF06424.7 KKK16161.1 - 0.023 15.0 0.7 0.055 13.8 0.5 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal GLE1 PF07817.8 KKK16161.1 - 0.034 13.0 0.6 0.06 12.2 0.4 1.3 1 0 0 1 1 1 0 GLE1-like protein Utp11 PF03998.8 KKK16162.1 - 5.9e-19 68.8 16.3 7.5e-19 68.5 11.3 1.1 1 0 0 1 1 1 1 Utp11 protein DUF3523 PF12037.3 KKK16162.1 - 5.1e-05 22.3 8.0 5.1e-05 22.3 5.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) SDA1 PF05285.7 KKK16162.1 - 0.0046 16.2 18.2 0.0058 15.9 12.6 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.7 KKK16162.1 - 0.23 9.3 25.1 0.28 9.0 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 KKK16162.1 - 0.35 10.4 32.1 0.24 11.0 11.2 2.2 1 1 1 2 2 2 0 Sigma-70, non-essential region VIT1 PF01988.14 KKK16162.1 - 0.82 9.1 2.8 1.2 8.5 1.9 1.3 1 0 0 1 1 1 0 VIT family XAP5 PF04921.9 KKK16162.1 - 2.4 7.6 11.4 4.3 6.8 7.9 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator RR_TM4-6 PF06459.7 KKK16162.1 - 8.6 6.1 12.8 13 5.6 8.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Histidinol_dh PF00815.15 KKK16163.1 - 2.3e-175 583.1 6.2 3.6e-175 582.5 4.3 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KKK16163.1 - 3.1e-24 84.3 0.0 7.8e-24 83.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KKK16163.1 - 4.2e-12 46.1 0.3 1.7e-11 44.2 0.2 2.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 KKK16163.1 - 0.0056 16.5 0.2 0.014 15.3 0.2 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF77 PF01910.12 KKK16164.1 - 1.2e-27 95.3 0.1 1.4e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 HAUS-augmin3 PF14932.1 KKK16165.1 - 0.079 12.1 1.5 0.13 11.4 1.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Daxx PF03344.10 KKK16165.1 - 0.08 11.4 5.5 0.14 10.5 3.8 1.3 1 0 0 1 1 1 0 Daxx Family Cut12 PF11500.3 KKK16165.1 - 0.29 10.8 3.7 0.67 9.6 2.6 1.5 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Baculo_PEP_C PF04513.7 KKK16165.1 - 0.41 10.4 1.8 1.1 9.1 1.1 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_3 PF13415.1 KKK16166.1 - 3e-31 106.8 10.1 1.6e-08 34.5 0.1 6.9 6 0 0 6 6 6 4 Galactose oxidase, central domain DUF4110 PF13422.1 KKK16166.1 - 1.4e-29 101.7 2.4 1.4e-29 101.7 1.6 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 KKK16166.1 - 1.2e-23 82.5 18.2 8.4e-07 28.6 0.0 6.8 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK16166.1 - 4.9e-16 58.3 4.2 0.00017 21.4 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KKK16166.1 - 3.8e-14 52.1 7.2 0.0023 18.0 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KKK16166.1 - 1e-11 44.0 10.4 0.005 16.5 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KKK16166.1 - 3e-08 33.0 0.7 0.27 10.8 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Abhydrolase_6 PF12697.2 KKK16167.1 - 3.6e-11 43.3 0.0 2e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK16167.1 - 7.2e-09 35.5 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK16167.1 - 1.2e-07 31.5 0.0 4.3e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK16167.1 - 0.029 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 KKK16167.1 - 0.074 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 KKK16167.1 - 0.12 11.5 0.0 0.67 9.1 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family Inhibitor_I53 PF11714.3 KKK16168.1 - 4.4 7.3 7.0 7.7 6.5 0.3 3.4 3 0 0 3 3 3 0 Thrombin inhibitor Madanin Pyridoxal_deC PF00282.14 KKK16169.1 - 1e-29 103.1 0.0 1.5e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KKK16169.1 - 1.2e-05 24.5 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 KKK16169.1 - 0.01 14.3 0.0 0.017 13.6 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) BRK PF07533.11 KKK16169.1 - 0.07 12.6 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 BRK domain Aminotran_5 PF00266.14 KKK16169.1 - 0.13 10.9 0.0 0.38 9.4 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class-V Proteasome PF00227.21 KKK16170.1 - 6.5e-47 159.2 0.0 8e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KKK16170.1 - 1.5e-14 52.9 2.6 3.3e-14 51.8 1.8 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal HEAT_2 PF13646.1 KKK16171.1 - 0.12 12.6 0.0 7.9 6.8 0.0 2.7 1 1 1 2 2 2 0 HEAT repeats Methyltransf_23 PF13489.1 KKK16172.1 - 7.6e-20 71.2 0.0 1.1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK16172.1 - 2.4e-08 33.7 0.0 8e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK16172.1 - 7.5e-08 32.7 0.0 3e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK16172.1 - 2.6e-07 31.0 0.0 5.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK16172.1 - 4e-07 30.6 0.0 8.7e-06 26.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK16172.1 - 1.9e-05 24.9 0.0 5.5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK16172.1 - 0.0034 17.3 0.0 0.0072 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KKK16172.1 - 0.028 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 KKK16172.1 - 0.051 12.6 0.0 0.085 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KKK16172.1 - 0.067 12.2 0.0 0.21 10.6 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KKK16172.1 - 0.17 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CENP-K PF11802.3 KKK16173.1 - 0.012 14.8 7.9 0.028 13.6 0.0 2.9 2 1 1 3 3 3 0 Centromere-associated protein K DUF4201 PF13870.1 KKK16173.1 - 0.63 9.4 16.2 0.21 11.0 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.5 KKK16173.1 - 0.85 9.7 17.8 0.31 11.1 2.3 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family CCDC84 PF14968.1 KKK16173.1 - 1.1 8.7 4.2 0.39 10.1 0.1 2.0 2 1 0 2 2 2 0 Coiled coil protein 84 COX16 PF14138.1 KKK16173.1 - 7.1 6.8 8.3 30 4.8 0.3 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 KH_1 PF00013.24 KKK16174.1 - 3.9e-42 141.7 3.6 3.1e-16 58.7 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KKK16174.1 - 4.8e-30 102.6 11.0 5e-11 41.9 1.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KKK16174.1 - 2.4e-11 43.0 3.7 0.014 14.9 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KKK16174.1 - 0.00024 20.6 1.2 1.1 8.9 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KKK16174.1 - 0.049 13.4 7.6 0.98 9.2 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain Helicase_C PF00271.26 KKK16176.1 - 1e-21 76.5 0.1 4.2e-18 64.9 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KKK16176.1 - 6.3e-21 74.6 0.0 2e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 KKK16176.1 - 6.3e-15 54.8 0.1 1.5e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 KKK16176.1 - 3.1e-09 36.3 0.0 1e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 HRDC domain WD40 PF00400.27 KKK16177.1 - 3.4e-17 61.5 0.8 0.00011 21.9 0.5 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Chitin_synth_2 PF03142.10 KKK16178.1 - 5.7e-229 760.9 0.0 8.9e-229 760.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KKK16178.1 - 5.4e-67 226.3 0.0 1.7e-63 214.8 0.0 3.1 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 KKK16178.1 - 7.4e-18 64.1 0.0 1.6e-08 34.2 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KKK16178.1 - 2.9e-17 63.0 1.4 2.9e-17 63.0 1.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 KKK16178.1 - 1.5e-15 56.6 1.6 1.4e-14 53.6 0.9 2.4 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 KKK16178.1 - 5.7e-15 55.7 0.0 2.8e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KKK16178.1 - 3.4e-06 26.4 0.0 8.9e-06 25.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KKK16178.1 - 0.0072 16.0 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 zf-Tim10_DDP PF02953.10 KKK16186.1 - 1.4e-20 72.3 3.9 1.8e-20 71.9 2.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RNA_lig_T4_1 PF09511.5 KKK16186.1 - 0.019 14.4 0.2 0.021 14.3 0.2 1.1 1 0 0 1 1 1 0 RNA ligase DUF842 PF05811.8 KKK16186.1 - 0.028 13.8 2.9 0.05 13.0 1.9 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF1546 PF07571.8 KKK16186.1 - 0.034 14.2 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) Arf PF00025.16 KKK16187.1 - 1.5e-25 89.4 0.0 3.5e-25 88.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KKK16187.1 - 9.5e-05 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KKK16187.1 - 0.0026 16.9 0.0 0.0052 16.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KKK16187.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 KKK16187.1 - 0.038 12.6 2.8 0.38 9.3 1.9 2.6 1 1 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.1 KKK16187.1 - 0.1 12.1 0.1 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ADH_N PF08240.7 KKK16188.1 - 4.7e-27 93.8 1.1 1e-26 92.8 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK16188.1 - 3.6e-18 65.3 0.4 6.6e-18 64.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 KKK16188.1 - 0.051 13.4 0.7 0.097 12.5 0.5 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pox_F11 PF04943.7 KKK16189.1 - 0.3 9.9 0.1 0.48 9.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Ndc80_HEC PF03801.8 KKK16190.1 - 4e-63 211.6 0.4 1.1e-62 210.2 0.0 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family Filament PF00038.16 KKK16190.1 - 0.00056 19.4 45.5 0.00099 18.6 14.1 2.6 2 0 0 2 2 2 2 Intermediate filament protein HSBP1 PF06825.7 KKK16190.1 - 0.004 16.6 2.3 0.32 10.5 0.2 3.8 3 1 0 3 3 3 1 Heat shock factor binding protein 1 CENP-F_leu_zip PF10473.4 KKK16190.1 - 0.012 15.4 14.7 0.012 15.4 10.2 4.1 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 KKK16190.1 - 0.16 10.1 37.3 0.047 11.9 10.9 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) NPV_P10 PF05531.7 KKK16190.1 - 2.1 8.6 14.7 3.4 7.9 0.3 4.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein HSP70 PF00012.15 KKK16190.1 - 3.4 5.4 31.6 0.14 10.0 10.3 2.6 2 1 1 3 3 3 0 Hsp70 protein Tropomyosin_1 PF12718.2 KKK16190.1 - 4 7.2 61.3 0.067 13.0 13.3 4.8 2 2 3 5 5 5 0 Tropomyosin like Reo_sigmaC PF04582.7 KKK16190.1 - 4.1 6.5 8.1 0.31 10.1 0.9 2.2 2 1 0 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 KKK16190.1 - 6.2 5.7 48.7 0.073 12.0 10.6 3.3 2 1 1 3 3 3 0 Autophagy protein Apg6 Pex14_N PF04695.8 KKK16191.1 - 3.6e-43 146.8 0.0 3.6e-43 146.8 0.0 4.1 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 KKK16191.1 - 0.081 12.5 0.0 0.081 12.5 0.0 2.9 3 0 0 3 3 3 0 IncA protein TRADD_N PF09034.5 KKK16191.1 - 0.082 12.9 1.1 0.16 11.9 0.7 1.5 1 0 0 1 1 1 0 TRADD, N-terminal domain Baculo_PEP_C PF04513.7 KKK16191.1 - 0.15 11.8 2.6 0.53 10.1 1.9 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF244 PF03112.9 KKK16191.1 - 0.6 9.6 2.7 0.47 9.9 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF FCH PF00611.18 KKK16192.1 - 7.5e-21 74.1 0.0 6.3e-20 71.1 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KKK16192.1 - 1.2e-12 46.9 0.0 2.7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK16192.1 - 1e-10 41.0 0.0 2.9e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KKK16192.1 - 4.1e-10 38.9 0.0 1.5e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain TTL PF03133.10 KKK16193.1 - 3e-56 190.5 0.0 4.6e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 KKK16193.1 - 3.3e-42 144.0 0.0 4.9e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 KKK16193.1 - 5.4e-05 22.1 0.0 0.0012 17.6 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KKK16193.1 - 0.0011 18.7 0.1 0.059 13.0 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KKK16193.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Glyco_transf_28 PF03033.15 KKK16193.1 - 0.12 12.0 0.0 0.32 10.7 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain ATP-grasp_3 PF02655.9 KKK16193.1 - 0.14 12.0 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Not1 PF04054.10 KKK16194.1 - 5.9e-139 463.1 0.1 3.4e-138 460.6 0.0 2.2 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 Seipin PF06775.9 KKK16194.1 - 2.4e-65 219.7 2.2 5.2e-65 218.7 1.5 1.6 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF3819 PF12842.2 KKK16194.1 - 3.4e-51 172.8 2.8 5.4e-51 172.1 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) SCO1-SenC PF02630.9 KKK16195.1 - 1.5e-58 197.2 0.0 2.2e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KKK16195.1 - 1.8e-05 24.4 0.1 3.7e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KKK16195.1 - 0.0013 18.7 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like APG6 PF04111.7 KKK16197.1 - 0.39 9.7 10.5 0.76 8.7 7.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KKK16197.1 - 2.1 6.0 2.7 2.9 5.6 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Yae1_N PF09811.4 KKK16198.1 - 0.043 13.3 0.2 0.093 12.2 0.1 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Col_cuticle_N PF01484.12 KKK16200.1 - 2.9 7.6 8.5 1.8 8.2 1.2 2.2 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Radical_SAM PF04055.16 KKK16201.1 - 1.2e-18 67.8 0.1 3.4e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KKK16201.1 - 3.7e-12 46.1 0.0 9.5e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KKK16201.1 - 0.058 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.14 KKK16202.1 - 3.8e-26 91.4 3.8 2.7e-25 88.6 1.0 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KKK16202.1 - 3.4e-23 81.9 0.2 5.6e-23 81.2 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KKK16202.1 - 6.3e-07 29.0 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KKK16202.1 - 0.0021 18.2 0.1 0.005 16.9 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain FBPase_glpX PF03320.8 KKK16202.1 - 0.053 12.1 0.0 4.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded ABC_tran PF00005.22 KKK16203.1 - 2e-12 47.5 0.0 3.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KKK16203.1 - 0.00014 21.1 0.1 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KKK16203.1 - 0.0043 16.9 1.1 0.056 13.3 0.8 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF4066 PF13278.1 KKK16203.1 - 0.068 12.4 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative amidotransferase AAA_21 PF13304.1 KKK16203.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ThiF PF00899.16 KKK16204.1 - 1.2e-16 60.7 0.1 2.4e-16 59.8 0.0 1.5 2 0 0 2 2 2 1 ThiF family Ytp1 PF10355.4 KKK16205.1 - 4.1e-89 298.3 14.3 4.1e-89 298.3 9.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KKK16205.1 - 2.7e-33 113.6 1.1 2.7e-33 113.6 0.8 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) RFX_DNA_binding PF02257.10 KKK16206.1 - 1.7e-29 101.7 0.2 5.5e-29 100.1 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain DUF2457 PF10446.4 KKK16207.1 - 0.001 17.8 16.2 0.001 17.8 11.2 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) YL1 PF05764.8 KKK16207.1 - 0.002 17.7 8.9 0.002 17.7 6.1 2.1 2 0 0 2 2 2 1 YL1 nuclear protein SGT1 PF07093.6 KKK16207.1 - 0.016 13.5 7.8 0.024 13.0 5.4 1.3 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.9 KKK16207.1 - 0.083 10.9 13.8 0.14 10.1 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KKK16207.1 - 0.16 9.8 16.2 0.25 9.2 11.2 1.3 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 KKK16207.1 - 0.7 8.8 10.5 0.033 13.1 1.7 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Nucleoplasmin PF03066.10 KKK16207.1 - 1 8.8 18.0 1.8 8.0 12.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KKK16207.1 - 1.7 8.1 17.3 0.14 11.7 7.9 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.7 KKK16207.1 - 4.7 6.3 20.6 10 5.2 14.3 1.5 1 0 0 1 1 1 0 NOA36 protein Tom22 PF04281.8 KKK16207.1 - 6 6.3 12.0 13 5.2 8.3 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 RVP PF00077.15 KKK16208.1 - 0.024 14.5 0.1 0.042 13.7 0.1 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KKK16208.1 - 0.045 14.2 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-met PF12874.2 KKK16209.1 - 1.7e-05 24.8 0.6 3.3e-05 23.9 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 KKK16209.1 - 0.044 13.0 0.9 0.085 12.1 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DNA_ligase_OB_2 PF14743.1 KKK16209.1 - 0.082 12.5 0.1 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 DNA ligase OB-like domain Pkinase PF00069.20 KKK16210.1 - 7.1e-54 182.6 0.2 9.5e-38 129.8 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16210.1 - 9.4e-25 87.1 0.4 1.5e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KKK16210.1 - 6.4e-05 22.0 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK16210.1 - 0.00027 20.0 0.0 0.0006 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK16210.1 - 0.00031 20.5 0.2 0.011 15.5 0.1 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK16210.1 - 0.0043 15.9 0.0 0.0071 15.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_C PF00433.19 KKK16210.1 - 0.013 15.9 0.0 0.037 14.5 0.0 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 KKK16210.1 - 0.078 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KKK16210.1 - 0.098 11.9 1.3 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF3441 PF11923.3 KKK16210.1 - 0.14 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) SpoIIIAH PF12685.2 KKK16210.1 - 0.19 11.1 0.9 0.31 10.5 0.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein CAP_GLY PF01302.20 KKK16211.1 - 1e-15 57.1 0.1 2.9e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain zf-U1 PF06220.7 KKK16211.1 - 3.4e-06 26.5 0.1 5.8e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger CCDC84 PF14968.1 KKK16211.1 - 0.0011 18.6 0.2 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Coiled coil protein 84 LRR_4 PF12799.2 KKK16211.1 - 9.6 5.9 5.9 6.6 6.4 0.8 2.8 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Tim54 PF11711.3 KKK16212.1 - 1.2e-122 409.2 0.0 2.9e-103 345.4 0.1 2.0 1 1 1 2 2 2 2 Inner membrane protein import complex subunit Tim54 Fungal_trans PF04082.13 KKK16213.1 - 4.3e-20 71.6 6.8 8.2e-20 70.7 4.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16213.1 - 3.3e-08 33.2 8.5 3.3e-08 33.2 5.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rox3 PF08633.5 KKK16214.1 - 2.8e-57 194.1 0.7 5.4e-57 193.2 0.5 1.4 1 0 0 1 1 1 1 Rox3 mediator complex subunit PBP1_TM PF14812.1 KKK16214.1 - 0.08 13.2 1.7 0.15 12.3 1.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.13 KKK16215.1 - 1.4e-20 73.3 0.2 2.2e-20 72.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16215.1 - 9.4e-10 38.2 12.3 1.7e-09 37.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IFP_35_N PF07334.8 KKK16215.1 - 0.16 11.9 0.3 0.45 10.5 0.2 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Glyco_hydro_114 PF03537.8 KKK16241.1 - 1.1e-28 98.7 0.1 1.9e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Acyl-CoA_dh_1 PF00441.19 KKK16249.1 - 7e-39 133.3 7.7 1.2e-38 132.6 5.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KKK16249.1 - 5.2e-27 94.6 0.9 1.4e-26 93.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KKK16249.1 - 2.3e-18 65.4 0.5 1e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KKK16249.1 - 1.5e-15 57.5 4.9 2.9e-15 56.6 3.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Metallophos PF00149.23 KKK16249.1 - 0.00044 19.7 1.6 0.0038 16.6 1.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK16249.1 - 0.0079 16.0 0.1 0.03 14.1 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HpaB_N PF11794.3 KKK16249.1 - 0.048 13.0 0.1 0.16 11.3 0.1 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Senescence PF06911.7 KKK16250.1 - 1.1e-46 158.7 2.3 1.6e-46 158.2 1.6 1.2 1 0 0 1 1 1 1 Senescence-associated protein Pkinase PF00069.20 KKK16251.1 - 8.6e-64 215.1 0.0 1.5e-63 214.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16251.1 - 8.9e-36 123.2 0.0 1e-30 106.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KKK16251.1 - 1.9e-05 23.8 0.0 0.012 14.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KKK16251.1 - 0.00048 19.9 0.1 0.0016 18.2 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KKK16251.1 - 0.00059 19.2 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KKK16251.1 - 0.018 14.1 0.2 0.053 12.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KKK16251.1 - 0.037 13.3 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M28 PF04389.12 KKK16252.1 - 2.9e-34 118.3 0.1 5.3e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KKK16252.1 - 3.3e-13 49.1 0.3 7.9e-13 47.9 0.2 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KKK16252.1 - 0.00029 20.3 4.3 0.00035 20.1 0.0 2.8 2 2 0 3 3 3 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KKK16252.1 - 0.055 12.2 0.0 0.32 9.7 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Nicastrin PF05450.10 KKK16252.1 - 0.07 12.3 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Dicty_REP PF05086.7 KKK16253.1 - 2.2 5.9 13.5 3.3 5.3 9.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.8 KKK16253.1 - 2.7 7.8 8.0 3.8 7.3 5.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 KKK16253.1 - 6.1 5.9 30.9 9.4 5.3 21.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cu_amine_oxid PF01179.15 KKK16254.1 - 1.4e-166 554.3 0.6 3.8e-165 549.6 0.4 2.0 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KKK16254.1 - 4.3e-05 23.5 0.0 9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KKK16254.1 - 0.00038 20.4 0.1 0.00074 19.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain ABC1 PF03109.11 KKK16255.1 - 3.2e-34 117.4 0.0 1e-32 112.6 0.0 2.6 2 0 0 2 2 2 1 ABC1 family Mannosyl_trans3 PF11051.3 KKK16256.1 - 7.4e-79 264.8 0.0 1.9e-78 263.5 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative GIDA PF01134.17 KKK16257.1 - 3.3e-154 513.4 0.0 4.1e-154 513.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KKK16257.1 - 5.9e-20 71.0 0.1 1.8e-19 69.5 0.1 1.8 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KKK16257.1 - 4.4e-07 29.9 0.5 9.1e-07 28.9 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK16257.1 - 3.5e-06 26.3 1.1 6.2e-06 25.5 0.8 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KKK16257.1 - 3e-05 23.1 2.0 0.06 12.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KKK16257.1 - 0.0011 18.5 0.2 0.0022 17.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KKK16257.1 - 0.0015 17.4 1.6 0.0015 17.4 1.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KKK16257.1 - 0.049 12.1 2.4 0.13 10.7 0.3 2.2 3 0 0 3 3 3 0 HI0933-like protein Gti1_Pac2 PF09729.4 KKK16258.1 - 2.6e-63 212.8 0.0 6.2e-63 211.6 0.0 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family DUF2404 PF10296.4 KKK16259.1 - 4.4e-05 23.5 0.0 7.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ARD PF03079.9 KKK16260.1 - 1.9e-45 154.6 0.3 2.2e-45 154.3 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KKK16260.1 - 4.1e-10 39.0 0.0 7.1e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KKK16260.1 - 4.9e-07 29.5 0.0 7.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KKK16260.1 - 0.0019 17.6 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Myb_DNA-binding PF00249.26 KKK16261.1 - 2.5e-05 24.2 0.0 4.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1183 PF06682.7 KKK16262.1 - 5.3e-62 210.2 0.0 7.8e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) PRA1 PF03208.14 KKK16262.1 - 0.25 10.6 2.6 0.43 9.9 1.8 1.5 1 1 0 1 1 1 0 PRA1 family protein UreF PF01730.11 KKK16263.1 - 4.6e-15 56.0 0.1 7.3e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 UreF BRE1 PF08647.6 KKK16264.1 - 5.5e-30 103.2 11.6 5.5e-30 103.2 8.0 7.0 5 2 2 7 7 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KKK16264.1 - 3.6e-09 36.4 10.0 6.2e-09 35.7 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK16264.1 - 1.2e-08 34.4 8.0 2.1e-08 33.7 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK16264.1 - 5.8e-08 32.2 10.2 1.1e-07 31.4 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK16264.1 - 6.8e-07 29.0 7.8 1.2e-06 28.2 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KKK16264.1 - 6.9e-06 25.7 10.7 1.2e-05 24.9 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KKK16264.1 - 2.9e-05 23.7 5.8 9.3e-05 22.0 4.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger TPR_MLP1_2 PF07926.7 KKK16264.1 - 0.0016 18.2 11.3 0.0016 18.2 7.9 6.3 2 2 3 6 6 6 2 TPR/MLP1/MLP2-like protein zf-rbx1 PF12678.2 KKK16264.1 - 0.0049 16.9 4.4 0.013 15.6 2.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KKK16264.1 - 0.0073 16.1 6.6 0.014 15.2 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KKK16264.1 - 0.014 14.9 7.2 0.071 12.7 5.3 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 KKK16264.1 - 0.02 14.7 6.2 0.041 13.7 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 KKK16264.1 - 0.03 13.8 3.4 0.059 12.9 2.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 KKK16264.1 - 0.25 11.1 3.6 0.49 10.2 2.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KKK16264.1 - 0.46 10.0 5.8 1.1 8.7 4.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2HC_2 PF13913.1 KKK16264.1 - 0.54 9.9 6.5 1 9.0 1.8 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PLAC9 PF15205.1 KKK16264.1 - 0.62 10.3 3.1 4.4 7.6 0.0 3.9 5 0 0 5 5 3 0 Placenta-specific protein 9 FYVE PF01363.16 KKK16264.1 - 0.98 9.3 11.7 12 5.8 8.1 2.5 1 1 1 2 2 2 0 FYVE zinc finger Reo_sigmaC PF04582.7 KKK16264.1 - 1.5 7.9 36.7 0.055 12.6 1.7 5.1 2 1 3 5 5 5 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KKK16264.1 - 3.7 7.6 45.3 0.19 11.8 1.5 5.8 3 1 2 6 6 6 0 Fibrinogen alpha/beta chain family zf-FCS PF06467.9 KKK16264.1 - 5.3 6.7 8.7 9.4 5.9 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif IncA PF04156.9 KKK16264.1 - 9.5 5.7 70.3 0.022 14.3 8.5 5.4 1 1 4 5 5 4 0 IncA protein Cu-oxidase_3 PF07732.10 KKK16278.1 - 2.8e-41 139.9 3.5 2.8e-41 139.9 2.5 3.9 3 2 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KKK16278.1 - 1.6e-39 135.3 0.8 1.8e-36 125.4 0.1 3.0 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK16278.1 - 1.7e-39 134.4 15.8 3.7e-38 130.1 2.6 3.1 3 1 0 3 3 3 2 Multicopper oxidase Alpha-amylase PF00128.19 KKK16279.1 - 1.2e-70 238.4 1.5 1.6e-70 238.0 1.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 KKK16279.1 - 4.3e-34 115.9 0.1 1.1e-33 114.6 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 KKK16279.1 - 2.6e-33 113.9 0.2 5.7e-33 112.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF3439 PF11921.3 KKK16279.1 - 9.6 5.9 17.4 29 4.4 12.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPR_11 PF13414.1 KKK16280.1 - 3.6e-11 42.5 12.8 5.7e-07 29.0 0.0 6.0 5 1 1 6 6 6 2 TPR repeat TPR_17 PF13431.1 KKK16280.1 - 5.7e-05 22.9 0.0 0.015 15.4 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK16280.1 - 7.2e-05 22.2 10.9 0.021 14.4 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK16280.1 - 0.00036 20.2 20.5 0.0034 17.1 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK16280.1 - 0.00044 19.8 1.8 1.5 8.7 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK16280.1 - 0.0035 17.9 0.6 0.026 15.2 0.1 5.1 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK16280.1 - 0.0038 16.8 5.7 0.55 10.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK16280.1 - 0.0069 16.9 0.5 0.0069 16.9 0.4 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK16280.1 - 0.02 14.8 16.1 0.28 11.1 0.0 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat Plug_translocon PF10559.4 KKK16280.1 - 0.031 13.7 0.1 0.064 12.7 0.1 1.6 1 0 0 1 1 1 0 Plug domain of Sec61p TPR_19 PF14559.1 KKK16280.1 - 3.1 8.2 14.9 0.17 12.2 1.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK16280.1 - 3.6 7.5 11.4 0.44 10.4 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_4 PF13637.1 KKK16281.1 - 2.1e-15 56.7 1.4 2.2e-10 40.7 0.1 4.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KKK16281.1 - 2e-07 31.2 0.3 0.00098 19.4 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK16281.1 - 1.7e-06 28.0 3.1 0.00018 21.6 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK16281.1 - 5.6e-05 22.9 0.7 0.016 15.3 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat KilA-N PF04383.8 KKK16281.1 - 0.0047 16.5 0.3 0.029 14.0 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain Baculo_PEP_C PF04513.7 KKK16281.1 - 0.011 15.5 1.1 0.019 14.8 0.2 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank PF00023.25 KKK16281.1 - 0.025 14.3 2.3 0.24 11.2 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat Sugar_tr PF00083.19 KKK16282.1 - 2.3e-36 125.3 24.2 6.3e-36 123.9 16.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK16282.1 - 1.2e-28 99.8 53.7 3e-27 95.2 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PGAP1 PF07819.8 KKK16283.1 - 1.1e-84 283.5 0.0 1.9e-84 282.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KKK16283.1 - 6.2e-09 35.7 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK16283.1 - 3.4e-06 27.0 0.1 7.8e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK16283.1 - 0.00071 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 KKK16283.1 - 0.0023 17.2 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.15 KKK16283.1 - 0.0052 16.2 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 KKK16283.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 KKK16283.1 - 0.072 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PsbH PF00737.15 KKK16284.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.5 3 0 0 3 3 3 0 Photosystem II 10 kDa phosphoprotein Complex1_LYR_1 PF13232.1 KKK16285.1 - 7.3e-05 22.8 0.4 0.00019 21.5 0.3 1.7 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KKK16285.1 - 0.0015 18.2 0.6 0.0036 17.0 0.4 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Cytotoxic PF09000.5 KKK16285.1 - 0.086 12.8 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Cytotoxic ResIII PF04851.10 KKK16286.1 - 3.4e-24 85.6 0.1 8.1e-23 81.1 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK16286.1 - 8.5e-15 54.3 0.0 2e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK16286.1 - 6.2e-13 48.5 0.0 5.2e-12 45.5 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KKK16286.1 - 0.0042 16.1 0.1 0.0096 14.9 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) U3_snoRNA_assoc PF08297.6 KKK16286.1 - 0.099 12.8 0.5 0.28 11.4 0.3 1.8 1 0 0 1 1 1 0 U3 snoRNA associated FAD_binding_3 PF01494.14 KKK16287.1 - 6.6e-15 55.0 0.1 9e-10 38.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK16287.1 - 1.2e-06 27.7 1.0 0.00046 19.2 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK16287.1 - 1.3e-06 27.6 1.0 1.3e-06 27.6 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KKK16287.1 - 3.7e-06 26.8 0.1 1.3e-05 25.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK16287.1 - 6.3e-06 26.5 0.5 3.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK16287.1 - 1.5e-05 25.0 0.3 3.8e-05 23.6 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK16287.1 - 2.4e-05 22.9 0.5 0.0003 19.3 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 KKK16287.1 - 0.001 18.0 0.8 0.0097 14.8 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KKK16287.1 - 0.0012 18.0 0.4 0.0012 18.0 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KKK16287.1 - 0.0019 17.1 0.2 0.005 15.7 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 KKK16287.1 - 0.0041 16.2 0.1 0.0086 15.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 KKK16287.1 - 0.0055 15.3 2.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase 3HCDH_N PF02737.13 KKK16287.1 - 0.058 13.0 0.2 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Myb_DNA-bind_6 PF13921.1 KKK16288.1 - 0.027 14.5 0.2 0.099 12.7 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain SWIRM PF04433.12 KKK16289.1 - 8.2e-35 118.8 0.1 1.7e-34 117.7 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 KKK16289.1 - 1.9e-06 27.9 0.1 6.1e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK16289.1 - 1.8e-05 24.6 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KKK16289.1 - 0.012 15.0 3.8 0.063 12.8 2.7 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type Methyltransf_10 PF05971.7 KKK16290.1 - 1.6e-68 231.0 0.0 2.2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 KKK16290.1 - 0.00056 19.3 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KKK16290.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK16290.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PLDc PF00614.17 KKK16291.1 - 1.8e-13 49.8 3.7 3.7e-07 29.7 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KKK16291.1 - 8.9e-13 48.0 0.0 1.9e-06 27.6 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain NMD3 PF04981.8 KKK16292.1 - 5.6e-73 244.9 3.1 7.4e-73 244.5 2.1 1.2 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 KKK16292.1 - 0.0043 16.9 2.6 3.5 7.6 0.1 3.4 3 0 0 3 3 3 2 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 KKK16292.1 - 0.28 11.0 7.6 2.7 7.8 3.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.16 KKK16292.1 - 0.34 10.8 4.4 0.97 9.3 1.0 2.5 2 0 0 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.7 KKK16292.1 - 8.4 6.2 7.8 55 3.6 0.1 2.9 2 1 0 2 2 2 0 zinc-ribbons Gly-zipper_OmpA PF13436.1 KKK16293.1 - 0.015 14.9 5.1 0.028 14.0 3.5 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 KKK16293.1 - 0.037 13.6 22.7 0.066 12.8 15.7 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain RuBisCO_large PF00016.15 KKK16293.1 - 0.042 12.7 2.3 0.056 12.2 1.6 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain DUF533 PF04391.7 KKK16293.1 - 0.053 12.8 4.4 0.092 12.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) SR-25 PF10500.4 KKK16293.1 - 0.3 10.5 13.3 0.4 10.1 9.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 KKK16293.1 - 0.67 10.0 19.6 1.1 9.3 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) BLVR PF06375.6 KKK16293.1 - 0.82 9.4 10.0 1.2 8.9 6.9 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Fungal_trans_2 PF11951.3 KKK16294.1 - 1e-06 27.6 0.0 1.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16294.1 - 0.0011 18.8 0.8 0.0011 18.8 0.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UAA PF08449.6 KKK16295.1 - 3.8e-72 242.7 10.6 8.3e-72 241.6 7.4 1.5 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KKK16295.1 - 1.2e-06 27.8 2.6 0.014 14.5 0.0 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 KKK16295.1 - 2.2e-06 27.7 9.0 2.2e-06 27.7 6.2 3.1 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 KKK16295.1 - 0.15 12.2 25.3 0.12 12.5 5.7 3.1 3 2 0 3 3 3 0 Multidrug resistance efflux transporter TPT PF03151.11 KKK16295.1 - 0.43 10.2 21.0 0.023 14.3 6.2 2.7 2 2 0 2 2 2 0 Triose-phosphate Transporter family Steroid_dh PF02544.11 KKK16296.1 - 3.5e-13 49.5 0.5 8.7e-13 48.2 0.2 1.8 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase TPPK_C PF12555.3 KKK16296.1 - 2.3 7.9 7.1 8.8 6.1 3.8 2.7 2 1 0 2 2 2 0 Thiamine pyrophosphokinase C terminal YbgT_YccB PF08173.6 KKK16296.1 - 7.9 6.4 9.5 18 5.2 6.0 2.1 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Rotamase_3 PF13616.1 KKK16297.1 - 1.4e-16 60.7 0.0 2.2e-16 60.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 KKK16297.1 - 1.9e-15 57.3 0.0 2.9e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KKK16297.1 - 7.4e-05 23.3 0.0 0.0001 22.9 0.0 1.2 1 1 0 1 1 1 1 PPIC-type PPIASE domain 2OG-FeII_Oxy_2 PF13532.1 KKK16298.1 - 4.3e-13 49.5 0.0 1.1e-12 48.1 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ras PF00071.17 KKK16299.1 - 6.2e-57 191.5 0.0 7.4e-57 191.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK16299.1 - 1.5e-20 73.8 0.0 2.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK16299.1 - 1e-14 54.1 0.0 1.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK16299.1 - 2.4e-06 26.8 0.0 3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KKK16299.1 - 1.2e-05 24.8 0.0 2.9e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KKK16299.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KKK16299.1 - 0.0097 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK16299.1 - 0.091 12.9 0.0 0.25 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Thiolase_N PF00108.18 KKK16325.1 - 1.1e-82 277.0 0.0 1.6e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK16325.1 - 1.1e-37 128.2 1.0 1.1e-37 128.2 0.7 2.5 2 1 2 4 4 4 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KKK16325.1 - 2.3e-05 24.0 2.8 4.3e-05 23.1 1.5 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Chal_sti_synt_N PF00195.14 KKK16325.1 - 0.099 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain MFS_1 PF07690.11 KKK16326.1 - 3.5e-45 154.2 49.1 2.1e-43 148.3 33.8 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK16326.1 - 2.6e-09 36.1 27.7 1.4e-08 33.7 10.1 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KKK16326.1 - 3.6e-09 35.5 29.6 0.00019 19.9 4.2 3.1 1 1 1 2 2 2 2 MFS/sugar transport protein Abhydrolase_6 PF12697.2 KKK16327.1 - 1.2e-21 77.6 0.8 1.2e-21 77.6 0.6 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK16327.1 - 4.6e-12 45.9 0.0 7.8e-10 38.6 0.0 2.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK16327.1 - 2.8e-08 33.6 0.0 9.7e-08 31.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KKK16327.1 - 0.0047 15.4 0.0 0.0064 15.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family EthD PF07110.6 KKK16327.1 - 0.036 15.0 0.1 5.6 7.9 0.0 2.7 2 0 0 2 2 2 0 EthD domain Glyoxalase PF00903.20 KKK16328.1 - 5.4e-33 113.6 0.0 8.4e-16 58.1 0.0 2.8 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KKK16328.1 - 2.1e-28 99.0 0.0 1.9e-14 54.1 0.0 2.9 2 0 0 2 2 2 2 Glyoxalase-like domain Fungal_trans PF04082.13 KKK16328.1 - 9.2e-20 70.5 0.1 1.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_4 PF13669.1 KKK16328.1 - 1.6e-14 53.8 0.0 9.9e-06 25.5 0.0 3.2 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KKK16328.1 - 9.6e-05 22.3 0.1 2 8.3 0.0 4.0 3 1 0 4 4 4 2 Glyoxalase-like domain Ig_2 PF13895.1 KKK16329.1 - 0.075 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Pkinase PF00069.20 KKK16330.1 - 3e-71 239.6 0.0 3.6e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16330.1 - 8.7e-31 106.9 0.0 1.1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK16330.1 - 0.0027 16.7 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK16330.1 - 0.0031 17.2 0.7 0.006 16.3 0.1 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK16330.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 KKK16330.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_C2 PF00648.16 KKK16331.1 - 2.9e-44 151.2 7.0 1.3e-24 86.7 1.0 3.2 3 1 0 3 3 3 2 Calpain family cysteine protease Abhydrolase_5 PF12695.2 KKK16334.1 - 1.5e-05 24.7 0.0 3.4e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK16334.1 - 0.00038 20.4 2.7 0.0012 18.8 1.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KKK16334.1 - 0.0054 16.3 0.1 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF4540 PF15073.1 KKK16334.1 - 0.011 16.3 0.3 0.017 15.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4540) JAB PF01398.16 KKK16335.1 - 2.9e-08 33.4 0.3 7.6e-07 28.8 0.2 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 KKK16335.1 - 0.063 12.5 0.4 0.72 9.0 0.1 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal Phage_XkdX PF09693.5 KKK16335.1 - 0.063 12.8 0.2 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) CK_II_beta PF01214.13 KKK16336.1 - 3.9e-71 238.3 0.1 5.4e-71 237.9 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit AdoHcyase PF05221.12 KKK16337.1 - 8.9e-137 454.3 0.0 1e-136 454.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KKK16337.1 - 5.5e-84 279.9 1.3 8.6e-84 279.3 0.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KKK16337.1 - 5.9e-06 25.5 0.1 1.3e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KKK16337.1 - 0.00045 19.6 0.2 0.00082 18.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KKK16337.1 - 0.001 19.0 0.1 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KKK16337.1 - 0.0074 15.8 0.1 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 KKK16337.1 - 0.048 13.7 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S15 PF02129.13 KKK16338.1 - 0.05 13.0 5.9 0.065 12.6 4.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Nucleo_P87 PF07267.6 KKK16338.1 - 1.7 7.1 4.4 2 6.9 3.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4661 PF15576.1 KKK16338.1 - 1.8 8.1 9.8 2.4 7.7 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DEAD PF00270.24 KKK16339.1 - 4.8e-46 156.3 0.0 1.3e-45 154.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK16339.1 - 1.4e-24 85.7 0.0 3.7e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK16339.1 - 0.0083 15.9 0.0 0.043 13.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KKK16339.1 - 0.0095 14.7 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain adh_short PF00106.20 KKK16340.1 - 2.7e-21 76.1 6.6 1.3e-11 44.7 0.0 3.4 2 2 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 KKK16340.1 - 4.4e-14 52.8 0.0 9.3e-09 35.3 0.0 2.5 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK16340.1 - 8.3e-11 41.8 2.2 8.4e-07 28.8 0.0 2.9 2 1 1 3 3 3 2 KR domain Epimerase PF01370.16 KKK16340.1 - 0.0012 18.3 0.0 0.037 13.4 0.0 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family DUF3843 PF12954.2 KKK16340.1 - 0.0075 15.3 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3843) zf-C2H2 PF00096.21 KKK16341.1 - 3.9e-18 64.6 49.4 1.2e-06 28.4 1.4 7.9 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK16341.1 - 1.5e-15 56.6 51.2 4e-08 33.1 0.7 8.1 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK16341.1 - 2.1e-13 49.5 51.5 0.00012 22.1 1.2 8.0 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.2 KKK16341.1 - 2.4e-10 40.2 20.0 0.0011 19.0 0.2 5.7 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK16341.1 - 4.6e-07 29.8 21.8 0.012 15.7 0.2 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KKK16341.1 - 1.3e-06 28.0 13.3 0.02 14.7 0.3 5.0 4 0 0 4 4 4 2 C2H2-type zinc finger HMG_box PF00505.14 KKK16342.1 - 1e-10 41.6 2.0 1e-10 41.6 1.4 3.3 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KKK16342.1 - 2.8e-09 37.1 15.4 6.4e-08 32.8 0.4 3.1 2 1 0 3 3 3 2 HMG-box domain CRAL_TRIO PF00650.15 KKK16344.1 - 3.5e-14 52.6 0.1 8.3e-14 51.3 0.1 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain SAM_decarbox PF01536.11 KKK16345.1 - 2.3e-85 286.1 0.0 7.2e-84 281.2 0.0 2.4 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1546 PF07571.8 KKK16345.1 - 1.1e-34 118.3 0.0 2.3e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KKK16345.1 - 6.7e-24 83.6 0.1 2.4e-23 81.8 0.1 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KKK16345.1 - 0.00034 20.6 0.2 0.0011 19.0 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KKK16345.1 - 0.013 15.5 0.1 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone VanZ PF04892.7 KKK16351.1 - 7.1e-10 38.9 0.5 1.1e-09 38.3 0.3 1.3 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 KKK16351.1 - 0.0051 15.8 0.1 0.0065 15.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) FtsX PF02687.16 KKK16351.1 - 0.03 14.0 1.8 2.7 7.7 0.5 2.3 2 1 0 2 2 2 0 FtsX-like permease family DUF4131 PF13567.1 KKK16351.1 - 7.9 5.8 7.7 42 3.4 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Bromodomain PF00439.20 KKK16352.1 - 2.6e-19 68.9 4.1 1.3e-18 66.7 0.2 3.3 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.8 KKK16352.1 - 3.6e-09 36.2 0.0 2.2e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 Bromodomain associated HisKA_3 PF07730.8 KKK16352.1 - 0.0074 16.6 0.9 0.18 12.1 0.0 3.1 2 0 0 2 2 2 1 Histidine kinase Nucleoplasmin PF03066.10 KKK16352.1 - 0.2 11.1 4.5 0.5 9.8 3.1 1.7 1 0 0 1 1 1 0 Nucleoplasmin Piwi PF02171.12 KKK16353.1 - 2.3e-68 230.4 0.0 3.3e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KKK16353.1 - 2.7e-19 68.2 0.0 6.6e-19 67.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KKK16353.1 - 3e-17 62.2 0.0 5.3e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain OmdA PF13376.1 KKK16354.1 - 6.8e-16 57.6 0.1 1.2e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated Isochorismatase PF00857.15 KKK16355.1 - 9.4e-21 74.5 0.0 1.7e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family DUF2809 PF10990.3 KKK16355.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) Fungal_trans_2 PF11951.3 KKK16356.1 - 0.00094 17.8 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CPSase_L_D2 PF02786.12 KKK16357.1 - 6.7e-114 378.4 0.1 6.1e-84 280.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KKK16357.1 - 4.4e-46 155.6 0.0 1.3e-45 154.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KKK16357.1 - 7.5e-44 149.4 0.0 4.5e-43 146.9 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 KKK16357.1 - 5.7e-43 145.9 0.0 1.1e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 KKK16357.1 - 4.1e-40 136.3 0.0 1e-39 135.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KKK16357.1 - 7.7e-40 135.4 0.0 5.1e-19 68.3 0.0 3.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 KKK16357.1 - 7.1e-36 123.4 0.0 1.7e-35 122.2 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 KKK16357.1 - 2.8e-35 121.7 0.1 1.3e-20 73.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 KKK16357.1 - 6.8e-22 77.2 0.0 4.4e-21 74.6 0.0 2.6 2 0 0 2 2 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 KKK16357.1 - 4e-20 71.8 0.0 7.5e-09 34.7 0.0 4.3 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK16357.1 - 1.1e-16 60.7 0.3 1.3e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KKK16357.1 - 9.9e-16 57.5 0.1 5.5e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KKK16357.1 - 1.9e-06 27.5 0.2 6.2e-05 22.5 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 KKK16357.1 - 5.9e-06 26.2 0.4 0.16 11.8 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KKK16357.1 - 0.0029 17.2 0.3 0.38 10.2 0.0 2.7 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Abhydrolase_3 PF07859.8 KKK16358.1 - 7.1e-40 136.8 0.0 9e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK16358.1 - 1.3e-05 24.4 0.0 0.0044 16.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK16358.1 - 1.4e-05 24.8 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KKK16358.1 - 0.0031 16.3 0.1 0.031 12.9 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 KKK16358.1 - 0.0053 16.0 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KKK16358.1 - 0.01 15.2 0.0 0.49 9.7 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KKK16358.1 - 0.04 12.4 0.1 3.8 5.9 0.0 2.5 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) AMP-binding PF00501.23 KKK16359.1 - 9.8e-77 258.0 0.0 1.2e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK16359.1 - 4.6e-12 46.7 1.1 1.1e-11 45.4 0.8 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.22 KKK16360.1 - 1.5e-24 86.8 0.0 1.2e-12 48.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KKK16360.1 - 6.5e-12 46.0 3.8 0.00031 20.7 0.0 3.3 2 1 0 3 3 3 3 AAA domain SbcCD_C PF13558.1 KKK16360.1 - 5.4e-06 26.2 0.0 0.067 13.1 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KKK16360.1 - 0.0062 16.0 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KKK16360.1 - 0.012 15.5 0.3 0.23 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.1 KKK16360.1 - 0.017 14.1 0.0 0.55 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 KKK16360.1 - 0.027 14.7 0.4 0.06 13.6 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK16360.1 - 0.053 13.4 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KKK16360.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 KKK16360.1 - 0.15 11.5 0.0 0.66 9.4 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Tmemb_cc2 PF10267.4 KKK16360.1 - 0.15 10.6 1.7 0.24 9.9 1.2 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein cobW PF02492.14 KKK16360.1 - 0.17 11.3 0.0 0.42 10.0 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3584 PF12128.3 KKK16360.1 - 0.17 9.1 0.2 0.24 8.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_22 PF13401.1 KKK16360.1 - 0.19 11.8 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.4 KKK16360.1 - 2.4 7.5 19.4 5.1 6.4 13.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ion_trans PF00520.26 KKK16361.1 - 8e-06 25.2 23.3 2.2e-05 23.8 16.1 1.7 1 1 0 1 1 1 1 Ion transport protein GGGtGRT PF14057.1 KKK16361.1 - 0.18 10.6 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 GGGtGRT protein Casein_kappa PF00997.13 KKK16361.1 - 0.19 11.4 0.7 19 4.9 0.0 2.4 2 0 0 2 2 2 0 Kappa casein NOA36 PF06524.7 KKK16361.1 - 2.5 7.2 6.4 6.3 5.9 4.5 1.6 1 0 0 1 1 1 0 NOA36 protein Synaptobrevin PF00957.16 KKK16363.1 - 9.5e-32 108.4 0.0 1.3e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KKK16363.1 - 1e-24 85.8 0.0 1.5e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF879 PF05947.7 KKK16363.1 - 0.06 11.7 0.0 0.08 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) DUF2628 PF10947.3 KKK16363.1 - 0.14 12.0 1.3 0.26 11.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Ost4 PF10215.4 KKK16365.1 - 4.9e-18 64.3 0.9 6.6e-18 63.9 0.6 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Fungal_trans PF04082.13 KKK16366.1 - 6e-10 38.4 0.0 1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16366.1 - 8.8e-10 38.3 4.0 1.6e-09 37.5 2.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.13 KKK16367.1 - 4.7e-41 140.6 0.0 1.6e-39 135.6 0.0 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Nucleoplasmin PF03066.10 KKK16367.1 - 1.1 8.7 11.1 3.1 7.2 7.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KKK16367.1 - 1.2 8.3 6.4 2.3 7.3 4.5 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 KKK16367.1 - 3.6 7.8 13.6 9.8 6.4 9.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 KKK16367.1 - 3.8 7.0 7.5 8.7 5.9 5.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 KKK16367.1 - 5.1 6.8 7.2 17 5.1 5.0 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal adh_short PF00106.20 KKK16368.1 - 6.4e-28 97.7 1.6 3.5e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KKK16368.1 - 1.9e-21 76.9 1.1 3.3e-20 72.8 0.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK16368.1 - 2e-12 47.1 0.5 7.2e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 KR domain Acetyltransf_1 PF00583.19 KKK16369.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family ABC2_membrane PF01061.19 KKK16370.1 - 3.1e-87 291.1 63.0 6.3e-49 165.9 16.9 3.3 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KKK16370.1 - 1.3e-38 130.7 5.0 4.1e-32 109.8 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 KKK16370.1 - 7.5e-36 123.4 0.0 1.5e-16 60.9 0.0 3.6 4 0 0 4 4 4 2 ABC transporter ABC_trans_N PF14510.1 KKK16370.1 - 1.3e-25 89.2 0.1 2.7e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KKK16370.1 - 5.2e-05 22.7 0.0 0.0039 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KKK16370.1 - 6.4e-05 22.1 17.5 6.4e-05 22.1 12.1 3.5 3 1 1 4 4 3 2 ABC-2 family transporter protein DUF258 PF03193.11 KKK16370.1 - 0.00087 18.5 0.0 0.03 13.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KKK16370.1 - 0.0049 16.7 0.0 0.81 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KKK16370.1 - 0.0054 16.2 0.9 0.044 13.2 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 KKK16370.1 - 0.009 15.2 0.0 0.77 8.9 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KKK16370.1 - 0.013 14.9 0.3 0.63 9.6 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KKK16370.1 - 0.035 14.0 0.1 0.38 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KKK16370.1 - 0.053 13.6 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KKK16370.1 - 0.06 13.6 0.0 0.65 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KKK16370.1 - 0.1 12.0 0.0 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KKK16370.1 - 0.12 12.1 0.0 25 4.7 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KKK16370.1 - 0.14 11.8 2.5 10 5.7 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.1 KKK16370.1 - 0.15 12.8 0.0 2.9 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KKK16370.1 - 0.16 12.4 0.0 34 4.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DUF3576 PF12100.3 KKK16371.1 - 0.028 14.4 0.1 0.8 9.7 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3576) DUF2404 PF10296.4 KKK16393.1 - 0.00011 22.2 0.0 0.00093 19.2 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) NAD_binding_8 PF13450.1 KKK16402.1 - 4e-09 36.3 0.0 8.2e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KKK16402.1 - 0.00011 21.4 0.0 0.00045 19.4 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KKK16402.1 - 0.00052 20.1 0.1 0.0012 18.9 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK16402.1 - 0.017 15.0 0.0 0.078 12.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK16402.1 - 0.021 13.9 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.19 KKK16402.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK16402.1 - 0.03 13.3 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KKK16402.1 - 0.063 13.0 0.1 0.92 9.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KKK16402.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KKK16402.1 - 0.13 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Med5 PF08689.5 KKK16403.1 - 6.4e-296 984.1 0.0 7.6e-296 983.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 zf-CCCH PF00642.19 KKK16403.1 - 0.18 11.5 0.1 0.38 10.4 0.1 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Iso_dh PF00180.15 KKK16413.1 - 2e-119 398.6 0.0 2.4e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CDP-OH_P_transf PF01066.16 KKK16414.1 - 3.3e-18 65.8 4.3 3.3e-18 65.8 3.0 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PqiA PF04403.8 KKK16414.1 - 0.01 15.4 0.2 0.025 14.1 0.2 1.6 1 0 0 1 1 1 0 Paraquat-inducible protein A PP2C PF00481.16 KKK16415.1 - 1.5e-33 116.2 0.1 3.5e-28 98.6 0.0 2.4 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.1 KKK16415.1 - 8.7e-06 25.2 0.0 2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KKK16415.1 - 0.0083 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) CNH PF00780.17 KKK16416.1 - 1.1e-82 277.6 0.0 5.9e-82 275.1 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 KKK16416.1 - 5.8e-41 139.5 0.0 2e-40 137.8 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KKK16416.1 - 1.2e-37 129.4 0.0 2.3e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KKK16416.1 - 7.6e-14 51.2 0.0 1.8e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.20 KKK16447.1 - 9e-72 241.3 0.0 1.3e-71 240.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16447.1 - 1.5e-37 129.0 0.0 4.5e-37 127.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK16447.1 - 0.0027 16.7 1.0 0.66 8.8 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Pox_ser-thr_kin PF05445.6 KKK16447.1 - 0.096 11.4 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Methyltransf_18 PF12847.2 KKK16448.1 - 6.5e-07 29.9 0.0 9.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK16448.1 - 1.6e-06 27.9 0.0 2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK16448.1 - 9.9e-05 22.7 0.0 0.00017 21.9 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK16448.1 - 0.00025 20.6 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK16448.1 - 0.00074 19.9 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KKK16448.1 - 0.0018 17.3 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 KKK16448.1 - 0.0035 16.7 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KKK16448.1 - 0.0045 17.0 0.5 0.012 15.6 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.7 KKK16448.1 - 0.0056 15.5 0.0 0.0069 15.2 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_16 PF10294.4 KKK16448.1 - 0.0087 15.5 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 KKK16448.1 - 0.01 15.2 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.14 KKK16448.1 - 0.042 13.3 0.1 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 KKK16448.1 - 0.09 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KKK16448.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KKK16448.1 - 0.15 11.1 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AMP-binding PF00501.23 KKK16449.1 - 3.7e-31 107.9 0.0 6.9e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KKK16449.1 - 4.7e-28 97.7 0.0 7.4e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KKK16449.1 - 7.2e-14 51.7 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KKK16449.1 - 0.00031 20.9 0.0 0.00081 19.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 KKK16449.1 - 0.0014 18.3 0.0 0.019 14.6 0.1 2.6 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 KKK16449.1 - 0.0034 16.3 0.0 0.055 12.3 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 KKK16449.1 - 0.0042 17.0 0.1 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KKK16449.1 - 0.034 13.4 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DXP_reductoisom PF02670.11 KKK16449.1 - 0.17 12.4 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.19 KKK16449.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KKK16449.1 - 0.3 9.9 0.0 0.53 9.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AvrE PF11725.3 KKK16450.1 - 0.2 8.6 3.5 0.27 8.2 2.4 1.1 1 0 0 1 1 1 0 Pathogenicity factor Methyltransf_2 PF00891.13 KKK16452.1 - 9.2e-27 93.7 0.0 2.2e-26 92.5 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KKK16452.1 - 0.00058 19.6 0.8 0.0016 18.2 0.5 1.8 1 0 0 1 1 1 1 Dimerisation domain PAS_9 PF13426.1 KKK16453.1 - 3.9e-30 104.2 0.0 1.3e-17 64.1 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 KKK16453.1 - 7.9e-19 67.5 0.0 8.7e-10 38.5 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 KKK16453.1 - 4.4e-14 52.2 0.0 0.00011 21.9 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 KKK16453.1 - 7.2e-14 50.8 5.4 7.2e-14 50.8 3.8 1.9 2 0 0 2 2 2 1 GATA zinc finger PAS_11 PF14598.1 KKK16453.1 - 2.4e-12 46.7 0.1 1.6e-06 28.0 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KKK16453.1 - 1.5e-10 41.0 0.0 0.046 13.7 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.1 KKK16453.1 - 0.006 16.4 0.0 0.057 13.3 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_2 PF08446.6 KKK16453.1 - 0.16 12.4 0.0 2.3 8.7 0.0 2.4 2 0 0 2 2 2 0 PAS fold Kinetocho_Slk19 PF12709.2 KKK16453.1 - 0.24 11.5 1.4 0.45 10.6 1.0 1.3 1 0 0 1 1 1 0 Central kinetochore-associated Telomerase_RBD PF12009.3 KKK16462.1 - 2.4e-43 147.2 0.1 4.8e-43 146.3 0.1 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KKK16462.1 - 3.2e-13 49.5 0.0 1.4e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.13 KKK16463.1 - 3.9e-26 91.8 0.0 5.9e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Synaphin PF05835.7 KKK16463.1 - 0.089 12.9 3.3 0.23 11.6 2.3 1.6 1 0 0 1 1 1 0 Synaphin protein AA_permease_2 PF13520.1 KKK16465.1 - 4.9e-65 219.7 47.3 5.9e-65 219.4 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK16465.1 - 1.9e-20 72.6 38.8 2.5e-20 72.2 26.9 1.2 1 0 0 1 1 1 1 Amino acid permease Bestrophin PF01062.16 KKK16466.1 - 1e-11 44.3 0.1 1.4e-11 43.8 0.0 1.2 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel SSP160 PF06933.6 KKK16466.1 - 0.058 11.3 0.0 0.07 11.1 0.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WD40 PF00400.27 KKK16467.1 - 3.6e-28 96.4 7.4 1.2e-10 40.8 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KKK16467.1 - 5.3e-19 67.9 0.0 1.1e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 KKK16467.1 - 0.0032 15.6 0.6 0.0032 15.6 0.4 2.1 2 1 0 3 3 3 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 KKK16467.1 - 0.071 12.6 0.0 1.3 8.5 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1749 PF08538.5 KKK16468.1 - 1.6e-94 316.1 0.0 1.8e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KKK16468.1 - 5.7e-08 32.9 0.0 9.6e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK16468.1 - 1.3e-06 28.1 0.0 3e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK16468.1 - 0.0017 18.0 0.0 0.02 14.4 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Acetyltransf_8 PF13523.1 KKK16469.1 - 3.5e-31 108.1 0.1 5e-31 107.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box-like PF12937.2 KKK16470.1 - 1.6e-07 30.9 3.1 4.4e-05 23.1 0.1 3.1 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 KKK16470.1 - 2.2e-05 23.9 1.7 0.00016 21.1 0.1 2.6 2 0 0 2 2 2 1 F-box domain Metallophos PF00149.23 KKK16471.1 - 4.5e-18 65.3 0.6 1.4e-17 63.7 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KKK16471.1 - 5.7e-16 58.3 0.2 1.6e-15 56.9 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KKK16471.1 - 3.8e-05 22.4 0.1 0.00023 19.8 0.0 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase fn3 PF00041.16 KKK16471.1 - 0.00031 20.8 0.1 0.00099 19.1 0.1 1.8 1 1 0 1 1 1 1 Fibronectin type III domain Peptidase_C14 PF00656.17 KKK16472.1 - 1.6e-51 175.4 0.0 2.3e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Glyoxalase_2 PF12681.2 KKK16473.1 - 3.6e-08 33.9 0.0 5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Pirin PF02678.11 KKK16474.1 - 5.4e-24 84.1 0.8 1.9e-23 82.3 0.5 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KKK16474.1 - 6.1e-06 25.6 1.3 0.00013 21.4 0.2 2.8 2 1 0 2 2 2 1 Cupin domain Abhydrolase_6 PF12697.2 KKK16475.1 - 8.5e-18 65.0 0.1 1.1e-17 64.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK16475.1 - 4.5e-11 42.4 0.0 7.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KKK16475.1 - 1.5e-09 37.7 0.0 3.4e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK16475.1 - 0.0004 20.0 0.0 0.00081 19.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.5 KKK16475.1 - 0.003 16.5 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.11 KKK16475.1 - 0.0092 15.4 0.0 7.9 5.8 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 KKK16475.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Ank_2 PF12796.2 KKK16476.1 - 5.7e-81 266.9 5.6 6.9e-18 64.7 0.0 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KKK16476.1 - 3e-57 187.7 2.0 1.1e-07 31.2 0.0 9.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KKK16476.1 - 2.4e-55 184.0 0.0 1.5e-09 38.1 0.0 6.9 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK16476.1 - 1.5e-49 164.9 0.2 2e-10 40.5 0.0 7.0 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK16476.1 - 3.1e-45 147.6 0.6 0.00049 20.0 0.0 9.8 10 0 0 10 10 10 9 Ankyrin repeat F-box-like PF12937.2 KKK16476.1 - 0.00011 21.8 0.6 0.00019 21.0 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK16476.1 - 0.011 15.4 0.5 0.018 14.7 0.4 1.3 1 0 0 1 1 1 0 F-box domain DNA_pol_phi PF04931.8 KKK16476.1 - 0.084 10.6 0.1 0.66 7.6 0.0 1.9 1 1 1 2 2 2 0 DNA polymerase phi CAP_GLY PF01302.20 KKK16513.1 - 1.9e-28 97.9 0.0 2.9e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KKK16513.1 - 7.2e-17 61.4 0.0 1.3e-16 60.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KKK16513.1 - 7.4e-05 22.0 0.0 0.00017 20.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family E1-E2_ATPase PF00122.15 KKK16514.1 - 1.4e-66 223.8 7.4 3.5e-65 219.2 5.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KKK16514.1 - 1.4e-29 104.0 0.1 3.3e-28 99.5 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KKK16514.1 - 5.8e-23 81.3 0.1 2.6e-22 79.2 0.0 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KKK16514.1 - 1.2e-21 76.4 0.0 2.4e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KKK16514.1 - 3.1e-17 61.8 0.0 1e-16 60.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KKK16514.1 - 1.7e-15 57.7 0.2 6.1e-15 55.8 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK16514.1 - 1.8e-07 31.0 2.0 8.7e-06 25.4 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fumarate_red_D PF02313.12 KKK16514.1 - 0.056 13.3 0.0 0.27 11.1 0.0 2.2 1 0 0 1 1 1 0 Fumarate reductase subunit D 14-3-3 PF00244.15 KKK16515.1 - 9.8e-115 381.5 2.9 1.2e-114 381.2 2.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 KKK16515.1 - 0.016 14.7 1.4 7.8 5.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_12 PF13424.1 KKK16515.1 - 0.018 14.9 0.4 9.3 6.2 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat MCM_N PF14551.1 KKK16515.1 - 0.75 10.2 3.3 4.4 7.8 0.3 2.3 1 1 1 2 2 2 0 MCM N-terminal domain Enolase_C PF00113.17 KKK16516.1 - 7.5e-153 507.7 0.1 9.7e-153 507.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KKK16516.1 - 3.6e-56 188.7 0.1 6.4e-56 187.9 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 KKK16516.1 - 0.028 13.3 0.1 0.75 8.6 0.0 2.4 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KKK16516.1 - 0.029 14.8 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain 3H PF02829.9 KKK16516.1 - 0.11 12.4 0.1 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 3H domain eIF3_subunit PF08597.5 KKK16517.1 - 3.9e-66 223.1 30.6 4.4e-66 222.9 21.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3245 PF11595.3 KKK16517.1 - 3.7 7.7 23.5 0.74 10.0 8.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) ATC_hydrolase PF14196.1 KKK16517.1 - 9.3 6.6 12.0 0.3 11.4 0.1 2.2 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase AAA PF00004.24 KKK16518.1 - 4.7e-43 146.5 0.0 7.8e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK16518.1 - 2.2e-07 31.0 0.0 1.1e-05 25.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 KKK16518.1 - 1.9e-06 27.9 0.0 6.5e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KKK16518.1 - 2.6e-06 27.2 0.1 5.5e-05 22.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KKK16518.1 - 3.1e-06 26.3 0.0 5.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KKK16518.1 - 6.9e-06 26.2 0.0 0.0013 18.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KKK16518.1 - 0.00033 19.6 0.0 0.00073 18.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KKK16518.1 - 0.00069 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KKK16518.1 - 0.0016 17.5 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KKK16518.1 - 0.002 18.9 0.4 0.0064 17.2 0.1 2.2 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KKK16518.1 - 0.0024 17.3 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KKK16518.1 - 0.0024 16.6 0.0 0.0052 15.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KKK16518.1 - 0.0029 17.5 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KKK16518.1 - 0.0044 16.5 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KKK16518.1 - 0.0056 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KKK16518.1 - 0.006 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 KKK16518.1 - 0.0062 16.8 0.1 0.02 15.2 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.6 KKK16518.1 - 0.0075 15.8 0.1 0.023 14.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK16518.1 - 0.0084 15.9 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KKK16518.1 - 0.01 15.2 0.1 0.07 12.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KKK16518.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 KKK16518.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KKK16518.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 KKK16518.1 - 0.024 14.2 0.1 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KKK16518.1 - 0.028 13.5 0.0 0.11 11.5 0.0 2.0 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.1 KKK16518.1 - 0.038 13.5 0.1 0.2 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KKK16518.1 - 0.041 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KKK16518.1 - 0.044 13.4 0.0 0.21 11.2 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 KKK16518.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KKK16518.1 - 0.073 12.7 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 KKK16518.1 - 0.074 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KKK16518.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.12 KKK16518.1 - 0.094 12.0 0.0 2.9 7.2 0.0 2.5 3 0 0 3 3 3 0 Thymidylate kinase Bap31 PF05529.7 KKK16533.1 - 0.76 9.2 3.6 1.1 8.6 2.5 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like V_ATPase_I PF01496.14 KKK16533.1 - 1.5 6.5 2.4 2 6.1 1.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS6_N PF14661.1 KKK16533.1 - 1.8 7.8 6.9 2.9 7.2 4.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus IncA PF04156.9 KKK16533.1 - 3.1 7.3 7.3 4.5 6.8 5.0 1.2 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 KKK16533.1 - 6.4 6.6 15.8 21 5.0 10.9 1.8 1 1 0 1 1 1 0 Basic region leucine zipper UPF0449 PF15136.1 KKK16533.1 - 6.6 7.0 9.1 0.31 11.2 2.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Pkinase PF00069.20 KKK16534.1 - 1.8e-41 142.0 0.2 1.2e-24 86.8 0.3 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16534.1 - 2.9e-14 52.7 0.4 2.3e-10 40.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase YopE PF03545.8 KKK16534.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) RIO1 PF01163.17 KKK16534.1 - 0.071 12.4 0.0 0.21 10.9 0.0 1.8 1 0 0 1 1 1 0 RIO1 family Ribonuclease_3 PF00636.21 KKK16541.1 - 7.2e-16 58.6 0.0 6.1e-15 55.6 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KKK16541.1 - 4.3e-12 46.1 0.0 7.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KKK16541.1 - 4.1e-05 24.0 0.1 0.0001 22.8 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif ER_lumen_recept PF00810.13 KKK16542.1 - 2.4e-57 193.5 8.8 4.6e-57 192.6 6.1 1.5 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KKK16542.1 - 0.014 14.9 7.1 2.5 7.7 0.1 3.7 3 0 0 3 3 3 0 PQ loop repeat Abhydrolase_5 PF12695.2 KKK16544.1 - 1.4e-09 37.8 0.5 2.2e-09 37.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK16544.1 - 5.9e-09 36.1 3.6 4.3e-08 33.3 2.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK16544.1 - 1e-06 28.1 0.0 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KKK16544.1 - 2.7e-05 23.6 0.1 0.0051 16.2 0.0 3.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KKK16544.1 - 3.5e-05 23.3 0.8 0.00015 21.3 0.5 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 KKK16544.1 - 0.0021 17.6 0.0 0.0081 15.7 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 KKK16544.1 - 0.0042 15.9 0.1 0.0071 15.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase Esterase_phd PF10503.4 KKK16544.1 - 0.014 14.6 0.1 0.027 13.7 0.1 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase TPT PF03151.11 KKK16545.1 - 7.1e-37 126.4 4.9 7.1e-37 126.4 3.4 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KKK16545.1 - 2.7e-08 33.0 13.9 2.2e-07 30.1 9.7 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KKK16545.1 - 0.00049 20.1 34.7 0.013 15.5 6.6 3.2 3 1 0 3 3 3 2 EamA-like transporter family Molybdopterin PF00384.17 KKK16546.1 - 6.5e-69 232.7 0.0 5.8e-35 120.8 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KKK16546.1 - 3.9e-20 71.4 0.1 1e-19 70.0 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KKK16546.1 - 3.3e-19 67.8 0.1 1.3e-18 65.8 0.1 2.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KKK16546.1 - 1.4e-16 60.4 0.1 4e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KKK16546.1 - 1.8e-08 33.9 0.6 1.8e-08 33.9 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KKK16546.1 - 0.0088 15.8 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain XRCC4 PF06632.7 KKK16547.1 - 3.3e-08 32.7 9.1 8.6e-08 31.4 6.3 1.8 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 KKK16547.1 - 0.0098 15.7 2.2 0.021 14.7 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) CCDC-167 PF15188.1 KKK16547.1 - 0.1 12.5 0.3 0.1 12.5 0.2 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 PUF PF00806.14 KKK16549.1 - 4.1e-36 120.4 3.6 2.2e-06 26.8 0.0 9.2 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Nup84_Nup100 PF04121.8 KKK16550.1 - 2.7e-64 217.1 6.2 3.8e-52 176.9 0.0 2.7 3 1 0 3 3 3 2 Nuclear pore protein 84 / 107 DUF1903 PF08991.5 KKK16551.1 - 1.8e-23 82.4 7.0 2.5e-23 82.0 4.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Cmc1 PF08583.5 KKK16551.1 - 0.054 13.2 3.1 0.054 13.2 2.1 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KKK16551.1 - 1.6 8.7 7.4 2.5 8.1 5.1 1.4 1 0 0 1 1 1 0 CHCH domain Rad60-SLD PF11976.3 KKK16552.1 - 4.8e-22 77.4 0.2 5.8e-22 77.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KKK16552.1 - 4.7e-09 35.5 0.1 5.9e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 KKK16552.1 - 0.16 11.6 0.3 0.26 11.0 0.2 1.4 1 1 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) CAF-1_p150 PF11600.3 KKK16553.1 - 0.094 12.0 12.6 0.16 11.3 8.8 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DBINO PF13892.1 KKK16553.1 - 0.15 12.0 9.0 0.21 11.5 6.3 1.2 1 0 0 1 1 1 0 DNA-binding domain APH PF01636.18 KKK16554.1 - 0.015 15.0 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_fiss_reg PF05308.6 KKK16555.1 - 1.5 8.0 4.6 2.5 7.3 3.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator E1-E2_ATPase PF00122.15 KKK16556.1 - 1.1e-58 198.0 1.9 2.3e-58 196.9 1.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK16556.1 - 1.9e-44 151.3 9.9 1.9e-44 151.3 6.9 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK16556.1 - 3.2e-27 96.3 0.0 1.6e-26 94.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK16556.1 - 3.3e-20 71.8 0.0 6.6e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK16556.1 - 7.1e-15 55.6 0.0 1.6e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK16556.1 - 1e-08 34.5 0.2 6.6e-08 31.9 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK16556.1 - 0.00089 18.9 1.7 0.0019 17.7 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1509 PF07420.6 KKK16557.1 - 2 7.5 14.9 1.4 8.1 9.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1509) CYSTM PF12734.2 KKK16558.1 - 8.7e-10 38.5 13.0 8.7e-10 38.5 9.0 5.2 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance ABC2_membrane PF01061.19 KKK16562.1 - 3.7e-18 65.4 21.0 4.4e-18 65.2 14.6 1.0 1 0 0 1 1 1 1 ABC-2 type transporter TMPIT PF07851.8 KKK16562.1 - 0.28 10.2 2.2 0.47 9.4 1.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF3754 PF12576.3 KKK16562.1 - 2.9 7.5 5.0 1.2 8.7 1.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) Aa_trans PF01490.13 KKK16563.1 - 3.4e-53 180.5 37.4 3.9e-53 180.4 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Dispanin PF04505.7 KKK16563.1 - 0.076 12.5 0.4 0.076 12.5 0.3 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Myb_DNA-binding PF00249.26 KKK16564.1 - 1.7e-09 37.5 0.0 2.4e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF1777 PF08648.7 KKK16564.1 - 0.31 10.7 75.6 0.0062 16.2 8.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1777) p450 PF00067.17 KKK16565.1 - 7.1e-62 209.4 0.0 8e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Redoxin PF08534.5 KKK16566.1 - 4.4e-38 130.1 0.0 4.9e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KKK16566.1 - 4.5e-13 48.9 0.0 5.8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1524 PF07510.6 KKK16567.1 - 5.2e-15 55.5 0.0 6.2e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 KKK16567.1 - 0.017 14.7 0.2 0.043 13.4 0.1 1.7 1 1 0 1 1 1 0 HNH endonuclease Med1 PF10744.4 KKK16589.1 - 1.9e-112 375.8 0.0 2.5e-112 375.5 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DUF159 PF02586.9 KKK16591.1 - 1.1e-56 191.6 0.0 1.7e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 TPR_12 PF13424.1 KKK16592.1 - 1.1e-07 31.6 0.6 0.0019 18.1 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK16592.1 - 1.1e-05 25.0 5.0 0.0012 18.5 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK16592.1 - 0.00012 21.5 8.3 0.0011 18.4 0.1 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KKK16592.1 - 0.0014 18.4 0.4 0.013 15.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK16592.1 - 0.0017 17.9 0.1 1.2 8.8 0.0 3.6 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 KKK16592.1 - 0.075 13.7 2.4 13 6.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK16592.1 - 0.19 11.6 2.3 2.5 8.1 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK16592.1 - 1.5 8.7 3.8 12 5.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 KKK16593.1 - 7.1e-61 200.0 25.1 2.7e-12 46.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KKK16593.1 - 0.0031 15.7 6.0 0.44 8.6 0.2 3.9 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KKK16593.1 - 0.0075 14.6 0.1 0.76 8.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Sdh5 PF03937.11 KKK16594.1 - 1.5e-23 82.2 1.5 1.9e-23 81.9 0.4 1.6 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Metallophos PF00149.23 KKK16599.1 - 6.7e-45 152.9 0.2 8.1e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 KKK16600.1 - 9.1e-15 53.8 10.8 1.4e-05 24.6 0.3 5.7 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK16600.1 - 1.8e-13 50.0 15.8 1.8e-07 30.7 2.1 3.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KKK16600.1 - 1.8e-07 30.2 9.2 0.53 10.5 0.3 6.6 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 KKK16600.1 - 0.073 13.1 8.0 6.4 7.1 0.1 5.2 3 1 2 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 KKK16600.1 - 1.2 9.5 13.9 56 4.6 0.1 6.0 6 1 0 6 6 6 0 Leucine rich repeat DUF2457 PF10446.4 KKK16601.1 - 4.6e-175 582.7 36.0 4.6e-175 582.7 25.0 2.7 2 2 0 2 2 2 1 Protein of unknown function (DUF2457) Arf PF00025.16 KKK16601.1 - 9e-63 210.6 0.0 1.4e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KKK16601.1 - 3.2e-09 35.9 0.6 7.7e-06 24.8 0.0 2.6 1 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KKK16601.1 - 2.8e-07 31.0 0.0 4e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KKK16601.1 - 3.6e-07 29.5 0.0 6.7e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KKK16601.1 - 2.4e-06 27.4 0.0 4.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KKK16601.1 - 0.00056 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KKK16601.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Abhydrolase_6 PF12697.2 KKK16602.1 - 0.00049 20.0 2.2 0.0013 18.7 1.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK16602.1 - 0.0016 18.1 0.1 0.0028 17.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KKK16602.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase bZIP_1 PF00170.16 KKK16662.1 - 4.5e-05 23.3 8.5 4.5e-05 23.3 5.9 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KKK16662.1 - 0.0011 18.7 8.9 0.0033 17.2 6.2 1.8 1 0 0 1 1 1 1 Basic region leucine zipper Fib_alpha PF08702.5 KKK16662.1 - 0.083 13.0 0.7 0.15 12.1 0.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Glutaredoxin2_C PF04399.8 KKK16662.1 - 0.14 11.7 0.5 0.23 11.0 0.4 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF4407 PF14362.1 KKK16662.1 - 0.18 10.7 3.3 0.2 10.5 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.3 KKK16662.1 - 0.44 10.2 5.6 3.9 7.2 3.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Stm1_N PF09598.5 KKK16663.1 - 2.9e-18 66.3 4.4 2.9e-18 66.3 3.0 4.5 3 2 0 3 3 3 1 Stm1 Ribosomal_L14e PF01929.12 KKK16663.1 - 1.4 9.3 5.3 4.9 7.5 0.9 2.3 2 0 0 2 2 2 0 Ribosomal protein L14 DUF3237 PF11578.3 KKK16664.1 - 2e-51 173.2 0.0 2.2e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) AA_permease PF00324.16 KKK16665.1 - 8.2e-59 199.1 32.9 1e-58 198.8 22.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK16665.1 - 1.1e-19 70.2 39.8 1.6e-19 69.7 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4064 PF13273.1 KKK16666.1 - 0.23 11.5 5.1 0.66 10.1 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) UNC-93 PF05978.11 KKK16667.1 - 0.012 15.1 5.5 0.23 10.9 0.1 2.4 1 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 FAD_binding_3 PF01494.14 KKK16668.1 - 6.2e-21 74.8 0.0 1.5e-20 73.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK16668.1 - 0.11 12.4 0.2 0.42 10.6 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 KKK16669.1 - 1.9e-29 102.4 31.3 1.9e-29 102.4 21.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK16669.1 - 1.9e-08 33.3 13.5 1.9e-08 33.3 9.4 3.0 2 2 1 3 3 3 2 Sugar (and other) transporter Ribosomal_L7Ae PF01248.21 KKK16670.1 - 1.8e-22 78.6 0.0 2.3e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KKK16670.1 - 0.00031 20.6 0.0 0.00031 20.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KKK16670.1 - 0.021 14.5 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Glyco_hydro_10 PF00331.15 KKK16671.1 - 9.8e-67 225.2 0.6 1.1e-66 225.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Abhydrolase_4 PF08386.5 KKK16672.1 - 6.9e-19 67.6 0.0 4.7e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 KKK16672.1 - 2.6e-11 43.5 0.0 6.1e-10 39.0 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK16672.1 - 9.1e-08 32.2 0.0 5.7e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family LSM PF01423.17 KKK16674.1 - 1.7e-18 65.8 0.1 2.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 KKK16675.1 - 7.8e-22 76.8 0.0 1.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KKK16675.1 - 2.8e-21 75.0 0.1 7.3e-21 73.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Aa_trans PF01490.13 KKK16676.1 - 1.2e-82 277.6 30.6 1.6e-82 277.2 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MPC PF03650.8 KKK16677.1 - 2e-35 121.2 0.0 2.3e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Phage_Coat_B PF05356.6 KKK16677.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage Coat protein B Clr5 PF14420.1 KKK16679.1 - 6.3e-13 48.4 0.8 1e-12 47.7 0.6 1.3 1 0 0 1 1 1 1 Clr5 domain ADH_N PF08240.7 KKK16680.1 - 2.7e-07 30.2 0.0 7.2e-07 28.9 0.0 1.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Rdx PF10262.4 KKK16682.1 - 7.4e-12 45.1 0.0 1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family Serglycin PF04360.7 KKK16682.1 - 0.07 12.8 8.0 0.096 12.4 5.5 1.2 1 0 0 1 1 1 0 Serglycin Gly-zipper_OmpA PF13436.1 KKK16682.1 - 1.5 8.4 5.2 0.66 9.6 1.4 1.9 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain PDEase_I PF00233.14 KKK16683.1 - 7.7e-47 160.0 0.0 1.3e-45 155.9 0.0 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KKK16683.1 - 0.066 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 HD domain SHMT PF00464.14 KKK16684.1 - 8.4e-197 653.3 0.0 9.9e-197 653.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KKK16684.1 - 0.0038 16.4 0.0 0.0076 15.4 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KKK16684.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Patatin PF01734.17 KKK16685.1 - 1.6e-27 96.7 0.1 3.5e-27 95.6 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase LysM PF01476.15 KKK16694.1 - 2.5e-12 46.4 0.2 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 LysM domain UPF0203 PF05254.7 KKK16694.1 - 0.15 11.8 0.2 20 5.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Rubella_E2 PF05749.6 KKK16694.1 - 3.4 6.8 10.7 1.3 8.1 1.8 2.1 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 DUF1244 PF06844.6 KKK16695.1 - 0.031 14.1 0.2 0.082 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Actin PF00022.14 KKK16710.1 - 5.6e-159 528.7 0.0 6.3e-159 528.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KKK16710.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pet127 PF08634.5 KKK16711.1 - 3e-125 416.9 1.2 3.8e-125 416.5 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GARS_A PF01071.14 KKK16712.1 - 9.1e-84 279.8 0.0 1.5e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KKK16712.1 - 2.3e-36 124.2 0.4 1.1e-35 122.0 0.0 2.5 3 0 0 3 3 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KKK16712.1 - 2.1e-32 112.2 0.0 4.8e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KKK16712.1 - 1.1e-26 92.8 0.1 2.5e-26 91.6 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KKK16712.1 - 4.1e-17 62.1 2.5 2e-16 59.9 1.7 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KKK16712.1 - 2.5e-11 43.6 0.0 7.8e-11 42.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KKK16712.1 - 1.1e-08 34.1 0.0 2.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KKK16712.1 - 8.2e-06 25.2 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KKK16712.1 - 1.3e-05 24.6 0.0 2.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 KKK16712.1 - 2.2e-05 24.3 0.0 8.8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.5 KKK16712.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KKK16712.1 - 0.0016 17.9 0.0 0.0037 16.7 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 KKK16712.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus tRNA_synt_1c_R1 PF04558.10 KKK16712.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 LRR_6 PF13516.1 KKK16713.1 - 7.3 7.0 12.6 2e+02 2.5 0.0 7.6 9 0 0 9 9 9 0 Leucine Rich repeat FA_desaturase PF00487.19 KKK16714.1 - 4.1e-29 101.8 24.1 5.6e-29 101.3 16.7 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KKK16714.1 - 0.051 13.6 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF3431 PF11913.3 KKK16715.1 - 2e-75 253.1 0.0 2.3e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SNARE PF05739.14 KKK16717.1 - 1.7e-17 62.8 0.7 1.7e-17 62.8 0.5 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KKK16717.1 - 1.1e-14 54.4 0.1 1.1e-14 54.4 0.0 2.8 3 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 KKK16717.1 - 0.013 15.0 1.0 0.013 15.0 0.7 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4H2 PF10146.4 KKK16717.1 - 0.017 15.1 0.6 0.38 10.7 0.0 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein Sed5p PF11416.3 KKK16717.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p KxDL PF10241.4 KKK16717.1 - 0.17 11.8 1.2 13 5.7 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein IncA PF04156.9 KKK16717.1 - 0.25 10.8 7.2 1.6 8.2 0.4 2.7 3 0 0 3 3 3 0 IncA protein NPV_P10 PF05531.7 KKK16717.1 - 0.26 11.5 4.8 18 5.6 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 KKK16717.1 - 4.1 7.1 12.7 0.74 9.6 2.0 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Peptidase_M50B PF13398.1 KKK16718.1 - 4.9e-26 91.3 16.6 4.9e-26 91.3 11.5 2.0 2 0 0 2 2 2 1 Peptidase M50B-like Patched PF02460.13 KKK16718.1 - 4.8 4.9 6.7 7.2 4.3 4.6 1.2 1 0 0 1 1 1 0 Patched family MLANA PF14991.1 KKK16718.1 - 7.7 6.5 9.1 1.9 8.4 1.0 2.8 1 1 1 2 2 2 0 Protein melan-A DUF1275 PF06912.6 KKK16719.1 - 3.4e-32 111.3 7.7 3.9e-32 111.1 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.1 KKK16719.1 - 1.3 8.3 9.3 3.3 7.0 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 KKK16734.1 - 2e-62 210.6 0.0 2.6e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16734.1 - 1e-30 106.7 0.0 1.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK16734.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KKK16734.1 - 0.097 12.3 0.0 0.68 9.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-UBR PF02207.15 KKK16736.1 - 2e-16 59.4 4.6 2e-16 59.4 3.2 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Nop14 PF04147.7 KKK16736.1 - 0.19 9.6 8.8 0.26 9.1 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family MCM PF00493.18 KKK16737.1 - 3.2e-138 460.0 0.0 4.7e-138 459.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KKK16737.1 - 1.1e-31 109.9 43.9 1.1e-31 109.9 30.4 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KKK16737.1 - 1e-17 64.7 0.0 2.3e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KKK16737.1 - 3.9e-09 35.9 0.1 9.5e-07 28.1 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK16737.1 - 4.2e-06 26.5 0.0 9.7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK16737.1 - 0.0011 18.5 0.0 0.0057 16.2 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KKK16737.1 - 0.0019 17.6 0.2 0.013 14.9 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.2 KKK16737.1 - 0.077 13.3 0.6 0.38 11.1 0.6 2.0 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-TFIIB PF13453.1 KKK16737.1 - 0.26 10.5 1.3 0.62 9.2 0.9 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Pyr_redox_2 PF07992.9 KKK16738.1 - 6.9e-07 29.3 0.0 2e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK16738.1 - 1e-05 25.6 0.0 0.023 14.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK16738.1 - 0.00042 20.2 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK16738.1 - 0.0069 16.1 0.0 0.027 14.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KKK16738.1 - 0.035 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KKK16738.1 - 0.051 12.0 0.0 0.087 11.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Cerato-platanin PF07249.7 KKK16739.1 - 4.4e-51 171.8 0.3 5.2e-51 171.6 0.2 1.1 1 0 0 1 1 1 1 Cerato-platanin Pterin_4a PF01329.14 KKK16741.1 - 0.085 12.6 0.0 0.085 12.6 0.0 1.6 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase Pkinase PF00069.20 KKK16742.1 - 2.5e-12 46.4 0.0 1.1e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16742.1 - 5.2e-08 32.2 0.0 0.0012 17.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KKK16742.1 - 0.0048 16.6 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KKK16742.1 - 0.087 11.7 0.0 0.95 8.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Lectin_C PF00059.16 KKK16744.1 - 0.00035 21.1 1.5 0.0005 20.6 0.5 1.7 2 0 0 2 2 2 1 Lectin C-type domain DUF4083 PF13314.1 KKK16744.1 - 0.17 11.7 0.6 0.28 11.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Sec62 PF03839.11 KKK16746.1 - 2.3e-54 184.1 0.2 4.2e-54 183.3 0.2 1.4 1 0 0 1 1 1 1 Translocation protein Sec62 VIT1 PF01988.14 KKK16746.1 - 0.4 10.1 2.5 0.91 8.9 1.8 1.7 1 1 0 1 1 1 0 VIT family Ribosomal_S21e PF01249.13 KKK16747.1 - 9.1e-41 137.6 0.2 4.1e-40 135.6 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S21e NUDIX PF00293.23 KKK16747.1 - 3e-12 46.3 0.0 6.2e-10 38.8 0.0 3.1 1 1 0 1 1 1 1 NUDIX domain tRNA-synt_2d PF01409.15 KKK16748.1 - 3.6e-88 294.9 0.0 4.9e-88 294.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KKK16748.1 - 1.2e-06 27.5 0.5 0.00023 20.0 0.0 3.6 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KKK16748.1 - 0.0005 19.6 0.0 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 KKK16748.1 - 0.063 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase EAF PF09816.4 KKK16762.1 - 1.1e-24 86.4 0.5 2.6e-24 85.2 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.18 KKK16762.1 - 5.5e-16 58.2 0.1 1.6e-15 56.7 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KKK16762.1 - 8.8e-08 32.0 2.0 5.3e-06 26.3 0.0 3.0 3 1 0 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.14 KKK16762.1 - 0.004 16.9 3.5 0.34 10.7 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Dor1 PF04124.7 KKK16763.1 - 4.7e-52 176.5 3.5 4.2e-41 140.5 2.9 2.3 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 KKK16763.1 - 0.00022 21.0 2.4 0.00026 20.7 0.3 2.2 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 KKK16763.1 - 0.07 13.0 1.0 0.21 11.4 0.7 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4328 PF14219.1 KKK16763.1 - 0.082 12.1 0.1 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) His_Phos_1 PF00300.17 KKK16764.1 - 5e-32 111.1 0.0 1.1e-31 110.0 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KKK16764.1 - 0.00019 20.8 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Med13_C PF06333.7 KKK16764.1 - 7 5.0 14.5 14 4.0 0.0 3.1 3 0 0 3 3 3 0 Mediator complex subunit 13 C-terminal FolB PF02152.13 KKK16765.1 - 1.2e-23 83.4 0.0 5.3e-20 71.6 0.1 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase Fungal_trans_2 PF11951.3 KKK16767.1 - 3.4e-17 62.1 0.8 1.6e-13 49.9 0.1 3.1 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16767.1 - 3.7e-07 29.9 11.5 3.7e-07 29.9 8.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK16767.1 - 0.0043 15.9 0.1 0.0082 15.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain BAR_2 PF10455.4 KKK16768.1 - 1.2e-14 53.9 0.3 1.3e-14 53.8 0.2 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KKK16768.1 - 0.0019 17.7 0.1 0.0019 17.7 0.1 1.1 1 0 0 1 1 1 1 BAR domain DASH_Dam1 PF08653.5 KKK16768.1 - 0.048 13.4 0.1 0.12 12.1 0.0 1.8 1 1 1 2 2 2 0 DASH complex subunit Dam1 Spc97_Spc98 PF04130.8 KKK16769.1 - 5.5e-135 450.7 1.4 7e-135 450.4 1.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Methyltransf_11 PF08241.7 KKK16770.1 - 1.1e-10 41.8 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK16770.1 - 3.2e-10 39.9 0.0 4.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK16770.1 - 6.9e-07 29.6 0.0 2e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK16770.1 - 1.1e-06 28.3 0.1 0.0089 15.6 0.0 2.4 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_4 PF02390.12 KKK16770.1 - 1.8e-05 23.8 0.0 6e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KKK16770.1 - 7.3e-05 23.3 0.0 0.0014 19.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KKK16770.1 - 0.0063 16.5 0.0 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KKK16770.1 - 0.0065 15.6 0.0 0.076 12.1 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 KKK16770.1 - 0.086 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_25 PF13649.1 KKK16770.1 - 0.1 12.9 0.0 0.55 10.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 KKK16771.1 - 1.5e-53 181.7 0.0 2e-51 174.6 0.0 2.6 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KKK16771.1 - 6.9e-08 32.8 0.2 4.1e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK16771.1 - 0.015 15.6 0.0 0.61 10.4 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KKK16771.1 - 0.022 14.4 2.1 0.054 13.1 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.1 KKK16771.1 - 0.084 12.5 0.0 0.34 10.6 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Proteasome PF00227.21 KKK16772.1 - 4.4e-53 179.3 0.0 5.6e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KKK16772.1 - 1.8e-10 39.8 0.1 4.9e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature KH_1 PF00013.24 KKK16773.1 - 0.0023 17.5 0.0 0.0086 15.7 0.0 2.0 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KKK16773.1 - 0.0094 15.5 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 KH domain CT47 PF15623.1 KKK16773.1 - 1.9 8.1 16.4 2.7 7.6 11.3 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 GAGA_bind PF06217.7 KKK16773.1 - 7.2 6.4 13.4 10 5.9 9.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family ATG22 PF11700.3 KKK16774.1 - 1.9e-128 428.9 26.9 2.2e-128 428.7 18.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KKK16774.1 - 1.4e-13 50.3 20.6 1.9e-06 26.8 2.2 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3611 PF12263.3 KKK16774.1 - 0.033 13.5 0.1 0.033 13.5 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3611) DUF2721 PF11026.3 KKK16774.1 - 0.25 10.9 0.0 0.25 10.9 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) E1_DerP2_DerF2 PF02221.10 KKK16775.1 - 9.2e-29 100.3 0.1 1.2e-28 100.0 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KKK16775.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.6 1 1 0 1 1 1 1 ML-like domain NPCBM_assoc PF10633.4 KKK16775.1 - 0.064 13.3 0.0 0.91 9.6 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Thiolase_N PF00108.18 KKK16776.1 - 5.2e-68 228.8 1.2 1e-67 227.9 0.8 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK16776.1 - 1.7e-39 134.0 0.1 3.5e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain HNH_2 PF13391.1 KKK16776.1 - 6.2e-10 38.7 0.2 1.3e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease ACP_syn_III PF08545.5 KKK16776.1 - 0.0012 18.5 0.6 0.042 13.5 0.1 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KKK16776.1 - 0.019 14.4 1.4 0.065 12.7 0.9 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 KKK16777.1 - 6.1e-52 176.4 0.0 4e-51 173.7 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK16777.1 - 9.9e-06 26.4 0.0 2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.1 KKK16778.1 - 2.1e-28 99.0 0.0 3e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK16778.1 - 2.4e-06 27.9 0.0 6.2e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK16778.1 - 0.0001 22.6 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK16778.1 - 0.00012 22.5 0.0 0.006 17.0 0.0 3.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK16778.1 - 0.00028 21.4 0.0 0.00077 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK16778.1 - 0.0028 17.6 0.1 0.0057 16.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK16778.1 - 0.0063 16.1 0.0 0.03 13.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DAO PF01266.19 KKK16779.1 - 1.1e-50 172.5 0.1 1.3e-50 172.3 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KKK16779.1 - 4.8e-07 28.9 0.0 2.7e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KKK16779.1 - 9.1e-07 28.9 0.0 8.9e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK16779.1 - 1.3e-06 28.2 0.1 0.023 14.5 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KKK16779.1 - 2.4e-06 26.7 0.0 0.00059 18.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK16779.1 - 9e-06 24.7 0.0 0.012 14.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 KKK16779.1 - 2.7e-05 23.0 0.0 0.071 11.7 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KKK16779.1 - 7.4e-05 22.7 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK16779.1 - 0.00032 21.0 0.1 0.0022 18.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK16779.1 - 0.0049 15.9 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KKK16779.1 - 0.0082 16.2 0.1 0.77 9.7 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK16779.1 - 0.016 13.6 0.1 3.5 5.9 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.14 KKK16779.1 - 0.018 14.1 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.14 KKK16779.1 - 0.02 13.9 0.1 0.3 10.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK16779.1 - 0.087 11.9 0.0 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.13 KKK16779.1 - 0.1 12.6 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain TBP PF00352.16 KKK16780.1 - 4.5e-70 231.0 0.1 4.3e-35 118.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KKK16780.1 - 0.00012 22.0 0.0 0.44 10.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 KKK16780.1 - 0.0064 16.8 0.1 0.0093 16.3 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease (pollen allergen) F-box PF00646.28 KKK16781.1 - 6.6e-05 22.4 0.0 0.00018 21.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KKK16781.1 - 0.0002 21.0 0.1 0.00049 19.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like SpoIIE PF07228.7 KKK16783.1 - 0.0017 18.0 0.1 0.005 16.5 0.1 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KKK16783.1 - 0.0041 16.5 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.27 KKK16784.1 - 8.9e-68 221.9 23.0 1.9e-08 33.8 0.2 11.8 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 KKK16784.1 - 4.4e-22 78.0 0.5 7.9e-22 77.2 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KKK16784.1 - 1.4e-06 26.7 1.0 0.057 11.5 0.0 5.4 5 2 0 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KKK16784.1 - 4.4e-05 22.4 1.9 0.63 8.7 0.0 4.1 2 1 1 4 4 4 2 Nup133 N terminal like DUF3312 PF11768.3 KKK16784.1 - 0.022 13.0 0.0 0.097 10.8 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) P34-Arc PF04045.9 KKK16785.1 - 1.7e-102 341.8 0.1 2e-102 341.5 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Kinesin PF00225.18 KKK16786.1 - 4.2e-90 301.8 0.1 4.2e-90 301.8 0.0 2.4 3 0 0 3 3 3 1 Kinesin motor domain Peptidase_C48 PF02902.14 KKK16789.1 - 1.8e-25 89.8 0.0 3.5e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_hydro_16 PF00722.16 KKK16790.1 - 0.0036 16.6 0.5 0.031 13.5 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PALP PF00291.20 KKK16791.1 - 1.3e-12 47.6 1.7 3.9e-10 39.4 0.1 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme AAA_13 PF13166.1 KKK16792.1 - 3e-05 22.7 0.6 0.00014 20.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain WEMBL PF05701.6 KKK16792.1 - 0.001 17.6 1.3 0.0016 17.0 0.9 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 KKK16792.1 - 0.0013 18.0 9.1 0.006 15.7 6.3 2.0 1 1 0 1 1 1 1 Reovirus sigma C capsid protein Spc7 PF08317.6 KKK16792.1 - 0.0017 17.1 2.4 0.0026 16.4 1.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 KKK16792.1 - 0.0017 18.2 6.0 0.05 13.4 0.4 2.9 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.8 KKK16792.1 - 0.0022 17.7 7.3 0.0041 16.8 0.7 3.1 1 1 1 3 3 3 2 Lipoprotein leucine-zipper Cast PF10174.4 KKK16792.1 - 0.0023 16.0 3.2 0.0023 16.0 2.2 1.4 2 0 0 2 2 2 1 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.6 KKK16792.1 - 0.0025 17.6 4.0 0.011 15.6 2.8 2.0 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 KKK16792.1 - 0.0034 17.1 1.8 0.44 10.3 1.4 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Atg14 PF10186.4 KKK16792.1 - 0.0068 15.3 1.2 0.0068 15.3 0.8 2.0 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4618 PF15397.1 KKK16792.1 - 0.0071 15.7 2.1 0.81 8.9 0.1 2.9 1 1 0 2 2 2 1 Domain of unknown function (DUF4618) HALZ PF02183.13 KKK16792.1 - 0.0079 15.8 0.2 3.2 7.5 0.0 3.1 3 1 0 3 3 2 1 Homeobox associated leucine zipper AIP3 PF03915.8 KKK16792.1 - 0.0084 15.0 3.7 0.016 14.1 2.6 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 TBPIP PF07106.8 KKK16792.1 - 0.03 13.8 0.3 0.062 12.8 0.2 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Transcrip_act PF04949.8 KKK16792.1 - 0.036 13.7 0.4 0.14 11.8 0.1 2.1 1 1 0 1 1 1 0 Transcriptional activator TSC22 PF01166.13 KKK16792.1 - 0.039 13.9 0.9 2.1 8.3 0.0 2.8 2 1 1 3 3 2 0 TSC-22/dip/bun family Myosin_tail_1 PF01576.14 KKK16792.1 - 0.052 11.2 3.5 0.016 12.9 0.6 1.4 2 0 0 2 2 2 0 Myosin tail NPV_P10 PF05531.7 KKK16792.1 - 0.053 13.7 5.2 0.16 12.2 0.6 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 KKK16792.1 - 0.064 13.2 0.2 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 KKK16792.1 - 0.069 13.0 3.2 0.29 11.0 0.4 2.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding COG7 PF10191.4 KKK16792.1 - 0.069 11.0 2.0 0.64 7.8 0.3 2.0 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) MscS_porin PF12795.2 KKK16792.1 - 0.087 12.1 0.4 0.32 10.2 0.2 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF972 PF06156.8 KKK16792.1 - 0.11 12.8 1.2 1.8 8.9 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 KKK16792.1 - 0.24 10.9 7.7 0.87 9.1 5.2 2.0 1 1 1 2 2 2 0 IncA protein COG5 PF10392.4 KKK16792.1 - 0.27 11.1 9.0 0.21 11.5 0.7 3.4 1 1 3 4 4 4 0 Golgi transport complex subunit 5 DUF1640 PF07798.6 KKK16792.1 - 0.29 11.1 3.5 6.5 6.7 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.7 KKK16792.1 - 0.34 10.7 6.1 0.06 13.1 1.3 1.8 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.9 KKK16792.1 - 0.54 9.8 5.1 0.24 11.0 0.7 2.3 2 1 1 3 3 2 0 Sec8 exocyst complex component specific domain Lge1 PF11488.3 KKK16792.1 - 2.4 8.4 6.0 6.8 6.9 1.8 3.1 2 1 0 2 2 1 0 Transcriptional regulatory protein LGE1 PAP2 PF01569.16 KKK16793.1 - 2.5e-13 49.8 4.6 2.5e-13 49.8 3.2 2.1 2 0 0 2 2 2 1 PAP2 superfamily DUF4512 PF14975.1 KKK16793.1 - 0.097 13.5 0.1 0.21 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) zf-HIT PF04438.11 KKK16794.1 - 3.4e-10 39.3 9.9 5.5e-10 38.7 6.8 1.3 1 0 0 1 1 1 1 HIT zinc finger RhoGAP PF00620.22 KKK16796.1 - 6.5e-37 126.4 0.5 1.3e-36 125.4 0.4 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KKK16796.1 - 2.1e-29 101.3 34.6 4.5e-12 45.8 4.0 4.8 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.7 KKK16796.1 - 4.1 6.8 7.6 0.11 11.9 0.3 2.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain DUF164 PF02591.10 KKK16796.1 - 5.7 6.8 11.0 4 7.3 0.1 3.7 3 0 0 3 3 3 0 Putative zinc ribbon domain UQ_con PF00179.21 KKK16797.1 - 7.6e-29 99.9 0.1 3e-15 55.8 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK16797.1 - 0.00043 20.0 0.1 1.6 8.4 0.0 3.2 2 1 0 2 2 2 2 Prokaryotic E2 family B 3Beta_HSD PF01073.14 KKK16798.1 - 6.9e-43 146.3 0.7 1.9e-23 82.5 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK16798.1 - 1.3e-18 67.3 0.0 8.4e-12 45.0 0.0 2.6 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK16798.1 - 2e-09 36.7 0.0 2.5e-08 33.1 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KKK16798.1 - 6.6e-06 25.2 0.0 0.0092 14.8 0.0 2.9 3 0 0 3 3 3 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KKK16798.1 - 0.013 14.4 0.0 0.14 11.0 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 KKK16798.1 - 0.048 13.3 0.0 0.19 11.3 0.0 2.0 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 KKK16798.1 - 0.12 12.4 0.0 5 7.0 0.0 2.6 3 0 0 3 3 3 0 NADH(P)-binding VWA_2 PF13519.1 KKK16799.1 - 2.9e-11 43.7 0.1 4e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KKK16799.1 - 3.3e-05 23.5 0.1 4.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 KKK16799.1 - 0.0028 17.1 0.6 0.012 15.1 0.4 2.2 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF4097 PF13349.1 KKK16799.1 - 0.048 13.1 0.2 0.08 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Nbl1_Borealin_N PF10444.4 KKK16800.1 - 2.8e-21 74.6 6.2 6.2e-21 73.5 4.3 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal TRP PF06011.7 KKK16801.1 - 2e-137 458.3 6.8 2.4e-137 458.1 4.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KKK16801.1 - 1.2e-40 138.8 0.4 1.8e-40 138.2 0.3 1.3 1 0 0 1 1 1 1 ML-like domain GTP_CH_N PF12471.3 KKK16802.1 - 2.9e-91 304.3 0.0 3.7e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KKK16802.1 - 2.6e-12 46.3 0.0 4.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF427 PF04248.7 KKK16802.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF427) GTP_cyclohydro2 PF00925.15 KKK16803.1 - 0.0078 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Ferric_reduct PF01794.14 KKK16804.1 - 1.5e-16 60.6 12.6 1.5e-16 60.6 8.7 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KKK16804.1 - 3.4e-16 59.5 0.0 1.3e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KKK16804.1 - 1e-14 54.2 0.0 1.1e-13 50.9 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KKK16804.1 - 0.014 15.9 0.1 0.95 10.0 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DHDPS PF00701.17 KKK16805.1 - 2.7e-39 134.5 0.0 3.4e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2014 PF09427.5 KKK16806.1 - 4.6e-105 350.4 0.0 7.5e-105 349.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 KKK16806.1 - 1.3e-18 66.4 0.1 3.4e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 KKK16806.1 - 0.01 15.7 3.9 0.012 15.5 1.0 2.2 2 0 0 2 2 2 0 bZIP transcription factor PBP PF01161.15 KKK16807.1 - 1.8e-23 82.9 0.0 2.4e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Copper-fist PF00649.13 KKK16808.1 - 8.9e-16 56.8 4.9 1.6e-15 56.0 3.4 1.4 1 0 0 1 1 1 1 Copper fist DNA binding domain Glyco_hydro_72 PF03198.9 KKK16809.1 - 8e-137 455.4 5.0 9.5e-137 455.1 3.4 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KKK16809.1 - 2.4e-06 26.9 0.1 2.2e-05 23.8 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DEAD PF00270.24 KKK16810.1 - 4.4e-33 114.1 0.5 7.2e-32 110.1 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK16810.1 - 1.9e-21 75.6 0.5 3.4e-21 74.8 0.4 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KKK16810.1 - 0.0077 15.9 0.7 0.065 12.9 0.1 2.6 2 1 1 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KKK16810.1 - 0.04 13.4 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain SH3_9 PF14604.1 KKK16811.1 - 4.3e-25 87.0 0.2 1.5e-12 46.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 KKK16811.1 - 5.1e-21 74.6 0.1 2.3e-20 72.5 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KKK16811.1 - 1.8e-18 65.6 0.1 1.3e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 KKK16811.1 - 7.6e-15 54.3 5.3 1.5e-14 53.4 3.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 KKK16811.1 - 0.00079 18.8 0.0 0.036 13.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 KKK16811.1 - 0.00093 19.3 0.1 0.023 14.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain Ax_dynein_light PF10211.4 KKK16811.1 - 0.013 15.3 3.4 0.013 15.3 2.3 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain C1_2 PF03107.11 KKK16811.1 - 0.028 14.5 8.3 0.05 13.7 5.8 1.4 1 0 0 1 1 1 0 C1 domain Neur_chan_memb PF02932.11 KKK16811.1 - 1.6 8.5 5.2 1.2 9.0 0.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region YlqD PF11068.3 KKK16811.1 - 4.9 7.1 11.5 3.8 7.5 1.0 3.3 3 0 0 3 3 3 0 YlqD protein Ras PF00071.17 KKK16823.1 - 5.1e-18 64.9 0.0 1.6e-17 63.3 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK16823.1 - 1.9e-08 34.7 0.0 2.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MCM PF00493.18 KKK16823.1 - 0.0018 17.1 0.0 0.0024 16.7 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family AAA_21 PF13304.1 KKK16823.1 - 0.0093 15.9 0.1 0.013 15.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KKK16823.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.15 KKK16823.1 - 0.014 14.1 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.1 KKK16823.1 - 0.03 13.8 0.1 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KKK16823.1 - 0.04 14.2 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 KKK16823.1 - 0.061 12.3 0.0 0.066 12.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.17 KKK16823.1 - 0.061 13.4 0.1 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 KKK16823.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 KKK16823.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PseudoU_synth_1 PF01416.15 KKK16824.1 - 1.2e-26 93.1 0.0 2.6e-21 76.0 0.0 2.9 3 0 0 3 3 3 2 tRNA pseudouridine synthase Nop PF01798.13 KKK16825.1 - 1.1e-54 183.8 0.6 2.2e-54 182.8 0.4 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KKK16825.1 - 1e-26 92.4 0.1 2e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KKK16825.1 - 4.5e-23 81.1 2.6 2.4e-22 78.8 1.8 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain HWE_HK PF07536.9 KKK16825.1 - 0.058 13.8 0.8 35 4.9 0.0 3.5 3 0 0 3 3 3 0 HWE histidine kinase RNA_pol_Rpb4 PF03874.11 KKK16826.1 - 1.6e-07 31.3 0.0 0.00075 19.4 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb4 PKI PF02827.11 KKK16826.1 - 1.1 9.3 4.2 2.8 8.1 2.9 1.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Pribosyltran_N PF13793.1 KKK16827.1 - 1.9e-31 108.2 0.0 5.1e-31 106.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KKK16827.1 - 4.4e-31 108.0 3.5 2.1e-26 92.8 0.9 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KKK16827.1 - 1.8e-10 40.5 0.3 4.7e-10 39.2 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KKK16827.1 - 0.0017 17.6 0.3 0.0028 16.8 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase vATP-synt_AC39 PF01992.11 KKK16828.1 - 1.1e-105 353.4 0.0 1.3e-105 353.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit UCH PF00443.24 KKK16829.1 - 7.3e-54 182.6 0.0 1e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK16829.1 - 4.7e-23 82.0 0.0 7.2e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KKK16829.1 - 0.00018 21.5 0.3 0.00018 21.5 0.2 2.4 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein P_C PF06640.6 KKK16830.1 - 0.095 12.6 4.9 0.088 12.7 3.4 1.1 1 0 0 1 1 1 0 P protein C-terminus CRAL_TRIO PF00650.15 KKK16831.1 - 1.3e-25 89.7 0.0 2.5e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK16831.1 - 1.9e-15 56.7 0.2 4e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KKK16831.1 - 0.0018 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.5 KKK16832.1 - 1.4e-29 101.5 1.3 1.9e-29 101.1 0.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ribosomal_60s PF00428.14 KKK16832.1 - 0.0041 17.4 0.1 0.0064 16.8 0.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Nitroreductase PF00881.19 KKK16833.1 - 8.3e-16 58.2 0.0 1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Ribosomal_L39 PF00832.15 KKK16834.1 - 9e-19 66.6 11.2 8.1e-13 47.6 1.1 2.1 2 0 0 2 2 2 2 Ribosomal L39 protein NmrA PF05368.8 KKK16835.1 - 9.6e-15 54.4 0.0 6.8e-14 51.6 0.0 1.9 1 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KKK16835.1 - 3.8e-13 49.8 0.1 6e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK16835.1 - 0.00014 21.4 0.1 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KKK16835.1 - 0.00025 21.0 0.4 0.00052 19.9 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 KKK16835.1 - 0.00087 19.2 0.2 0.0021 17.9 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KKK16835.1 - 0.00098 19.4 0.1 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KKK16835.1 - 0.0044 16.7 0.1 0.0087 15.7 0.1 1.5 1 0 0 1 1 1 1 KR domain GFO_IDH_MocA PF01408.17 KKK16835.1 - 0.011 16.2 0.1 0.023 15.2 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3Beta_HSD PF01073.14 KKK16835.1 - 0.022 13.4 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KKK16835.1 - 0.028 14.4 0.3 0.064 13.2 0.1 1.7 2 0 0 2 2 1 0 TrkA-N domain RmlD_sub_bind PF04321.12 KKK16835.1 - 0.031 13.1 0.1 0.048 12.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.12 KKK16835.1 - 0.041 14.3 0.8 0.11 12.9 0.6 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KKK16835.1 - 0.06 12.9 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF552 PF04472.7 KKK16835.1 - 0.084 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF552) Ldh_1_N PF00056.18 KKK16835.1 - 0.095 12.5 0.7 0.21 11.4 0.5 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 KKK16835.1 - 0.14 11.9 0.3 0.34 10.7 0.2 1.6 1 0 0 1 1 1 0 ThiF family ABC_membrane PF00664.18 KKK16836.1 - 6.5e-93 311.1 35.4 1.8e-47 162.0 10.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KKK16836.1 - 1.6e-52 177.4 0.0 9.6e-33 113.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 KKK16836.1 - 1.3e-08 34.2 0.6 0.00055 19.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KKK16836.1 - 1.5e-08 34.1 1.4 9e-06 25.0 0.5 3.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK16836.1 - 3.3e-07 30.5 0.1 0.9 9.4 0.0 3.4 3 0 0 3 3 3 3 AAA domain DUF258 PF03193.11 KKK16836.1 - 4.3e-07 29.2 0.0 0.043 13.0 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KKK16836.1 - 1.1e-06 29.4 0.2 0.057 14.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK16836.1 - 1.4e-05 25.2 4.8 0.025 14.5 0.0 3.6 4 1 0 4 4 3 2 AAA ATPase domain AAA_25 PF13481.1 KKK16836.1 - 2.5e-05 23.7 0.1 0.31 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK16836.1 - 6.5e-05 23.0 0.6 0.52 10.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KKK16836.1 - 8.9e-05 22.7 0.2 2 8.6 0.1 3.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK16836.1 - 0.00033 20.5 0.0 0.66 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KKK16836.1 - 0.00058 19.7 0.7 0.91 9.3 0.0 3.4 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit ABC_ATPase PF09818.4 KKK16836.1 - 0.001 17.7 0.5 0.0032 16.1 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.1 KKK16836.1 - 0.0012 19.1 0.0 1.9 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KKK16836.1 - 0.0014 18.3 0.0 2.4 7.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KKK16836.1 - 0.0017 17.9 1.3 2 7.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KKK16836.1 - 0.0025 18.1 2.5 0.54 10.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KKK16836.1 - 0.0026 17.2 3.2 2.5 7.4 0.1 3.6 4 0 0 4 4 4 2 AAA-like domain AAA_19 PF13245.1 KKK16836.1 - 0.0046 16.6 0.2 1.5 8.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 KKK16836.1 - 0.0074 15.3 0.2 2.3 7.2 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin Rad17 PF03215.10 KKK16836.1 - 0.0078 14.9 0.1 0.16 10.6 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KKK16836.1 - 0.0078 16.3 0.1 2.1 8.5 0.0 3.2 3 0 0 3 3 2 1 RNA helicase MobB PF03205.9 KKK16836.1 - 0.0091 15.7 0.1 5.6 6.6 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KKK16836.1 - 0.0092 15.4 0.3 0.87 8.9 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 KKK16836.1 - 0.012 15.5 0.0 1.4 8.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 KKK16836.1 - 0.041 13.6 0.2 4.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 PRK PF00485.13 KKK16836.1 - 0.052 13.1 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RXT2_N PF08595.6 KKK16836.1 - 0.052 13.3 0.3 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal AAA_28 PF13521.1 KKK16836.1 - 0.074 13.0 0.9 4.1 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KKK16836.1 - 0.31 11.0 2.0 19 5.2 0.0 3.5 4 0 0 4 4 4 0 50S ribosome-binding GTPase CDC45 PF02724.9 KKK16836.1 - 1.2 7.1 7.5 0.052 11.5 0.2 1.9 2 0 0 2 2 2 0 CDC45-like protein Glyco_transf_22 PF03901.12 KKK16837.1 - 9.3e-45 153.3 16.1 1.3e-44 152.8 11.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XPC-binding PF09280.6 KKK16838.1 - 1.9e-23 81.6 12.6 3.8e-23 80.7 8.7 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KKK16838.1 - 7e-20 70.2 0.7 1.6e-09 37.2 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KKK16838.1 - 4.5e-19 67.6 0.7 7.9e-19 66.8 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KKK16838.1 - 5e-08 32.5 0.4 8.2e-08 31.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KKK16838.1 - 0.00035 20.4 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 KKK16838.1 - 0.00085 18.8 0.0 0.7 9.5 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rap1_C PF11626.3 KKK16838.1 - 0.001 18.8 0.0 0.09 12.6 0.0 2.4 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain CUE PF02845.11 KKK16838.1 - 0.011 15.2 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 CUE domain DUF2407 PF10302.4 KKK16838.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.7 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Skp1 PF01466.14 KKK16839.1 - 1.5e-39 133.8 2.2 1.5e-39 133.8 1.6 1.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KKK16839.1 - 1.2e-24 86.1 0.0 3e-24 84.8 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KKK16839.1 - 0.057 13.4 0.4 0.095 12.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) PPR_2 PF13041.1 KKK16840.1 - 1.7e-45 152.7 4.5 3.1e-10 39.8 0.0 12.6 9 4 5 14 14 14 10 PPR repeat family PPR_3 PF13812.1 KKK16840.1 - 6.8e-30 100.8 25.1 0.00062 19.8 0.1 15.9 18 0 0 18 18 18 6 Pentatricopeptide repeat domain PPR PF01535.15 KKK16840.1 - 9.5e-23 78.5 15.7 0.00042 20.1 0.0 13.3 16 1 0 16 16 16 5 PPR repeat PPR_1 PF12854.2 KKK16840.1 - 3.1e-21 74.5 0.0 1.3e-06 27.8 0.0 9.3 9 1 0 9 9 9 3 PPR repeat RPM2 PF08579.6 KKK16840.1 - 1.5e-09 38.0 0.0 0.00021 21.4 0.0 5.2 5 0 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 KKK16840.1 - 0.00087 18.2 0.1 0.085 11.7 0.0 3.2 3 0 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.1 KKK16840.1 - 0.079 13.6 14.2 31 5.5 0.0 9.2 10 2 1 11 11 11 0 Tetratricopeptide repeat PNPOx_C PF10590.4 KKK16841.1 - 2e-20 71.9 5.9 9.5e-20 69.8 2.9 2.4 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KKK16841.1 - 3.3e-10 39.8 0.0 0.001 19.0 0.0 2.8 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase DUF1206 PF06724.6 KKK16842.1 - 0.0048 16.6 1.1 0.0099 15.6 0.8 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1206) GHMP_kinases_N PF00288.21 KKK16843.1 - 3e-14 52.8 3.1 4.4e-14 52.3 1.2 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KKK16843.1 - 4.1e-10 39.7 0.0 8.8e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Zn_clus PF00172.13 KKK16844.1 - 4.7e-08 32.8 8.6 9.8e-08 31.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK16844.1 - 2e-06 26.8 0.0 3.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-amylase_C PF02806.13 KKK16845.1 - 3.2e-25 88.0 0.0 8.4e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KKK16845.1 - 3.9e-19 69.1 0.0 3.3e-14 53.0 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KKK16845.1 - 1.6e-16 60.0 0.1 3.9e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.1 KKK16845.1 - 0.011 14.1 0.2 0.017 13.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Glyco_hydro_92 PF07971.7 KKK16846.1 - 9.3e-67 225.7 1.8 1.2e-66 225.4 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 TPR_12 PF13424.1 KKK16847.1 - 2.7e-20 72.1 3.6 2.6e-06 27.2 0.1 5.2 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 KKK16847.1 - 1e-11 44.3 2.4 0.079 12.9 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat DUF676 PF05057.9 KKK16847.1 - 3.2e-05 23.3 0.0 0.00014 21.2 0.0 1.8 1 1 1 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KKK16847.1 - 0.00034 20.2 0.0 0.00066 19.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KKK16847.1 - 0.00042 20.2 0.0 0.00083 19.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_2 PF07719.12 KKK16847.1 - 0.0048 16.7 1.4 1.9 8.5 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Abhydrolase_5 PF12695.2 KKK16847.1 - 0.0052 16.5 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_11 PF13414.1 KKK16847.1 - 0.014 15.0 0.1 1 9.0 0.0 3.0 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.1 KKK16847.1 - 0.027 15.1 0.1 1 10.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4518 PF15008.1 KKK16847.1 - 0.035 13.1 0.1 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Lipase_3 PF01764.20 KKK16847.1 - 0.038 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) TPR_1 PF00515.23 KKK16847.1 - 0.083 12.5 1.3 2.1 8.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Amidase PF01425.16 KKK16848.1 - 4.1e-70 236.8 0.0 3.1e-69 233.9 0.0 2.1 1 1 0 1 1 1 1 Amidase ThiF PF00899.16 KKK16848.1 - 1.3e-39 135.0 0.0 4.1e-39 133.5 0.0 1.8 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 KKK16848.1 - 1.3e-28 98.3 0.1 2.8e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KKK16848.1 - 1.8e-11 44.3 0.0 3.8e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KKK16848.1 - 0.0038 17.3 0.0 0.013 15.5 0.0 2.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KKK16848.1 - 0.0053 15.7 0.7 0.013 14.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 KKK16848.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KKK16848.1 - 0.086 13.0 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KKK16848.1 - 0.099 11.6 1.0 0.2 10.6 0.7 1.5 1 0 0 1 1 1 0 FAD binding domain DPBB_1 PF03330.13 KKK16849.1 - 2.4e-08 33.8 0.0 4e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KKK16849.1 - 0.069 12.8 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Barwin family CBFD_NFYB_HMF PF00808.18 KKK16850.1 - 2.2e-14 53.2 2.2 2.3e-14 53.2 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK16850.1 - 0.0016 18.5 0.1 0.0029 17.6 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_C14 PF00656.17 KKK16851.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KKK16851.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain She9_MDM33 PF05546.6 KKK16852.1 - 3e-94 314.4 8.2 4.3e-94 313.9 5.7 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family DUF1183 PF06682.7 KKK16852.1 - 0.012 15.2 0.4 0.012 15.2 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) PsbH PF00737.15 KKK16852.1 - 0.02 14.4 1.0 0.02 14.4 0.7 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein DRY_EERY PF09750.4 KKK16852.1 - 0.052 13.6 4.8 0.12 12.4 3.4 1.6 1 0 0 1 1 1 0 Alternative splicing regulator DUF2175 PF09943.4 KKK16852.1 - 0.058 13.4 2.1 0.069 13.2 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) COX4 PF02936.9 KKK16853.1 - 2.2e-52 176.5 0.4 3.2e-52 176.0 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.3 KKK16853.1 - 1.6 9.1 7.4 0.35 11.2 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1289 PF06945.8 KKK16853.1 - 4.6 6.7 5.4 6.7 6.2 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Cofilin_ADF PF00241.15 KKK16854.1 - 3e-23 82.0 0.0 3.3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1262 PF06880.6 KKK16854.1 - 0.086 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1262) SH3_9 PF14604.1 KKK16855.1 - 2.4e-06 27.0 0.1 5.4e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK16855.1 - 0.0024 17.2 0.0 0.0054 16.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain EphA2_TM PF14575.1 KKK16855.1 - 0.078 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KKK16855.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Voltage_CLC PF00654.15 KKK16856.1 - 3.9e-91 305.7 31.0 3.9e-91 305.7 21.5 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KKK16856.1 - 1.4e-14 53.5 0.0 7.4e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain Pmp3 PF01679.12 KKK16857.1 - 3.3e-20 71.5 6.1 4.2e-20 71.1 4.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4106 PF13388.1 KKK16857.1 - 1.5 7.7 7.0 1.5 7.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) UCR_TM PF02921.9 KKK16858.1 - 3.5e-20 71.9 1.7 6.1e-20 71.2 1.2 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KKK16858.1 - 2.7e-17 62.0 0.2 6.9e-17 60.8 0.1 1.7 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain ATP-synt_ab PF00006.20 KKK16859.1 - 1e-61 208.1 0.0 1.6e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KKK16859.1 - 9.9e-27 93.6 0.3 2e-26 92.6 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KKK16859.1 - 7.2e-24 83.7 1.7 1.9e-23 82.4 0.6 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 KKK16859.1 - 0.0013 17.8 0.2 0.0023 17.0 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 KKK16859.1 - 0.0033 16.8 0.1 0.043 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KKK16859.1 - 0.0097 15.6 0.0 0.034 13.8 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 KKK16859.1 - 0.013 15.6 0.1 0.51 10.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK16859.1 - 0.014 15.3 0.2 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KKK16859.1 - 0.023 13.8 0.2 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KKK16859.1 - 0.024 14.3 0.1 0.066 12.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 KKK16859.1 - 0.042 13.5 0.2 1.3 8.7 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KKK16859.1 - 0.058 13.5 0.2 0.27 11.3 0.0 2.2 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KKK16859.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KKK16859.1 - 0.15 10.9 0.9 0.67 8.7 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain GN3L_Grn1 PF08701.6 KKK16860.1 - 2.1e-24 85.2 16.8 2.1e-24 85.2 11.7 2.4 3 0 0 3 3 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KKK16860.1 - 2.3e-22 79.1 0.2 1.1e-15 57.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KKK16860.1 - 4.4e-06 26.6 4.5 0.33 10.7 0.0 4.0 3 2 2 5 5 5 3 Dynamin family GTP_EFTU PF00009.22 KKK16860.1 - 4.9e-06 26.1 1.3 0.088 12.2 0.0 2.8 3 0 0 3 3 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KKK16860.1 - 1.3e-05 24.5 0.1 0.00011 21.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KKK16860.1 - 0.0011 18.2 0.2 0.0018 17.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KKK16860.1 - 0.002 18.6 1.3 0.2 12.1 0.0 2.7 3 0 0 3 3 2 1 Miro-like protein AIG1 PF04548.11 KKK16860.1 - 0.0073 15.4 0.4 0.5 9.4 0.0 2.8 3 0 0 3 3 3 1 AIG1 family Daxx PF03344.10 KKK16860.1 - 0.029 12.8 22.7 0.041 12.3 15.7 1.3 1 0 0 1 1 1 0 Daxx Family ORC3_N PF07034.6 KKK16860.1 - 0.036 13.0 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus ArgK PF03308.11 KKK16860.1 - 0.036 12.8 0.1 0.036 12.8 0.0 1.9 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 KKK16860.1 - 0.072 13.3 5.2 0.2 11.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 KKK16860.1 - 0.085 12.3 0.0 1.2 8.5 0.0 2.4 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Nop14 PF04147.7 KKK16860.1 - 0.69 7.7 36.7 1.1 7.0 25.5 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 KKK16860.1 - 5.5 6.7 21.1 11 5.8 14.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SseC PF04888.7 KKK16874.1 - 0.29 10.4 6.8 0.75 9.0 4.7 1.6 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family MFS_1 PF07690.11 KKK16875.1 - 3.3e-33 114.8 29.1 3.3e-33 114.8 20.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Synaptobrevin PF00957.16 KKK16876.1 - 6.4e-14 51.3 0.2 1e-13 50.6 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KKK16876.1 - 6.3e-11 41.6 0.0 1.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tbf5 PF06331.7 KKK16876.1 - 0.003 17.2 0.1 0.0068 16.1 0.0 1.5 2 0 0 2 2 2 1 Transcription factor TFIIH complex subunit Tfb5 Phage_Integr_2 PF13009.1 KKK16876.1 - 0.082 11.8 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative phage integrase DUF3472 PF11958.3 KKK16877.1 - 7.4e-13 49.2 0.0 9.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) 3-HAO PF06052.7 KKK16878.1 - 2.9e-55 185.8 0.1 3.6e-55 185.5 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KKK16878.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain T2SI PF02501.12 KKK16878.1 - 0.15 12.0 0.7 8.4 6.4 0.1 2.4 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein I AA_permease PF00324.16 KKK16881.1 - 2.8e-57 194.1 37.5 8.4e-32 110.1 12.4 1.9 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KKK16881.1 - 1.2e-21 76.7 32.7 2.7e-21 75.6 22.7 1.5 1 1 0 1 1 1 1 Amino acid permease PHD PF00628.24 KKK16882.1 - 3.2e-05 23.5 10.0 5.8e-05 22.7 6.9 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 KKK16882.1 - 7.1e-05 23.1 0.1 7.1e-05 23.1 0.1 3.4 4 2 0 4 4 4 1 SET domain Aconitase PF00330.15 KKK16883.1 - 1.9e-181 603.6 0.0 2.3e-181 603.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KKK16883.1 - 8.6e-37 126.1 0.0 1.3e-27 96.4 0.0 2.6 1 1 1 2 2 2 2 Aconitase C-terminal domain Aldo_ket_red PF00248.16 KKK16884.1 - 5.1e-62 209.2 0.0 5.8e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glycos_transf_4 PF00953.16 KKK16885.1 - 1.6e-30 105.9 14.2 1.6e-30 105.9 9.8 2.5 3 1 0 3 3 3 1 Glycosyl transferase family 4 WD40 PF00400.27 KKK16886.1 - 4.7e-22 76.9 11.3 2.2e-05 24.1 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Vert_HS_TF PF06546.6 KKK16886.1 - 0.012 15.0 0.1 0.019 14.4 0.1 1.2 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor WD40 PF00400.27 KKK16887.1 - 1.9e-20 71.8 18.4 3.4e-07 29.8 0.1 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat zf-MYND PF01753.13 KKK16887.1 - 0.0037 17.0 3.9 0.0083 15.9 2.7 1.6 1 0 0 1 1 1 1 MYND finger SET PF00856.23 KKK16887.1 - 0.0051 17.1 2.0 0.11 12.7 0.0 3.4 4 0 0 4 4 4 1 SET domain TPR_9 PF13371.1 KKK16887.1 - 0.049 13.4 1.5 0.11 12.3 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat BAR_2 PF10455.4 KKK16888.1 - 2.7e-40 138.1 0.1 4e-40 137.5 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KKK16888.1 - 2.8e-14 53.2 0.2 3e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 BAR domain ATP-synt_B PF00430.13 KKK16888.1 - 0.0029 17.4 2.1 0.0089 15.8 1.4 1.7 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) NOGCT PF08155.6 KKK16889.1 - 7.6e-29 99.1 4.5 1.5e-28 98.2 3.1 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 KKK16889.1 - 2.1e-27 94.7 0.4 4.9e-27 93.5 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KKK16889.1 - 4.6e-15 55.6 0.0 1.1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK16889.1 - 1.4e-07 30.9 0.0 3.4e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KKK16889.1 - 1.5e-05 25.4 0.0 0.00031 21.2 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein CbiA PF01656.18 KKK16889.1 - 0.027 13.8 0.3 0.079 12.3 0.0 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dynamin_N PF00350.18 KKK16889.1 - 0.029 14.1 0.0 7 6.4 0.0 2.7 1 1 1 2 2 2 0 Dynamin family SbcD_C PF12320.3 KKK16889.1 - 0.042 13.8 0.1 0.042 13.8 0.1 2.4 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain DUF619 PF04768.8 KKK16890.1 - 1.6e-53 180.5 0.0 2.2e-52 176.9 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF619) Acetyltransf_1 PF00583.19 KKK16891.1 - 7.1e-11 41.9 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK16891.1 - 4.7e-09 36.2 0.0 7.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK16891.1 - 0.00098 18.9 0.0 0.0041 16.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KKK16891.1 - 0.0058 16.5 0.0 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KKK16891.1 - 0.032 14.1 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KKK16891.1 - 0.039 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KKK16891.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arv1 PF04161.8 KKK16892.1 - 1.9e-40 139.0 0.0 1.4e-35 123.1 0.0 2.2 2 0 0 2 2 2 2 Arv1-like family ATP_synt_H PF05493.8 KKK16893.1 - 6.9e-05 22.8 0.1 8.9e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase subunit H PsbX PF06596.6 KKK16893.1 - 0.0098 15.5 0.5 0.012 15.2 0.4 1.2 1 0 0 1 1 1 1 Photosystem II reaction centre X protein (PsbX) ApoO PF09769.4 KKK16893.1 - 0.025 14.3 0.0 0.025 14.2 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein O FixQ PF05545.6 KKK16893.1 - 0.1 12.2 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Ureide_permease PF07168.6 KKK16893.1 - 0.12 10.9 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Ureide permease SRR1 PF07985.7 KKK16898.1 - 2.3e-08 33.8 0.0 3.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.2 KKK16898.1 - 0.033 14.2 0.7 0.08 12.9 0.2 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) APC10 PF03256.11 KKK16898.1 - 0.078 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Abhydrolase_5 PF12695.2 KKK16922.1 - 1.6e-23 83.0 0.0 2.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK16922.1 - 1.5e-19 70.7 0.0 2.1e-18 67.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KKK16922.1 - 5.6e-08 31.6 0.2 0.01 14.3 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 KKK16922.1 - 4.5e-07 29.6 0.0 5.2e-05 22.9 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK16922.1 - 6.4e-06 25.5 0.0 9.9e-05 21.6 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 KKK16922.1 - 4e-05 23.1 0.0 0.00013 21.5 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KKK16922.1 - 5.7e-05 22.7 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KKK16922.1 - 9.6e-05 21.9 0.0 0.14 11.5 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KKK16922.1 - 0.00011 21.9 0.0 0.01 15.5 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KKK16922.1 - 0.00068 18.9 0.0 0.088 12.0 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.8 KKK16922.1 - 0.0048 16.5 0.0 0.029 13.9 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 KKK16922.1 - 0.0073 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 KKK16922.1 - 0.012 15.4 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF2305 PF10230.4 KKK16922.1 - 0.015 14.6 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF818 PF05677.7 KKK16922.1 - 0.02 13.6 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Lipase_3 PF01764.20 KKK16922.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 KKK16922.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Proteasome PF00227.21 KKK16923.1 - 5.4e-47 159.5 0.2 6.2e-47 159.3 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.12 KKK16923.1 - 0.12 11.9 0.0 15 5.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Cyclin PF08613.6 KKK16924.1 - 9.5e-38 129.9 6.2 2.7e-22 79.7 0.0 3.2 3 0 0 3 3 3 2 Cyclin RhoGEF PF00621.15 KKK16925.1 - 1.9e-36 125.6 0.0 4e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 KKK16925.1 - 1.2e-15 57.6 1.8 2.6e-15 56.5 1.2 1.5 1 0 0 1 1 1 1 BAR domain Peptidase_C48 PF02902.14 KKK16925.1 - 0.0012 18.5 0.0 0.0036 16.9 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GATase_5 PF13507.1 KKK16927.1 - 1.1e-98 329.3 0.0 1.7e-98 328.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KKK16927.1 - 2e-42 144.7 0.4 1.5e-20 73.7 0.1 2.8 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KKK16927.1 - 2.7e-26 91.6 0.4 2.1e-25 88.8 0.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Fungal_trans PF04082.13 KKK16928.1 - 2.5e-09 36.3 0.4 5e-09 35.4 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16928.1 - 3e-06 27.0 11.8 5.3e-06 26.2 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.3 KKK16928.1 - 4.7 6.3 13.3 10 5.2 9.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.11 KKK16929.1 - 4.6e-43 147.2 32.6 4.6e-43 147.2 22.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK16929.1 - 2.2e-10 39.7 11.3 2.2e-10 39.7 7.8 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KKK16929.1 - 2.1e-09 36.1 2.1 4.1e-09 35.2 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Asp PF00026.18 KKK16930.1 - 1e-47 162.9 2.2 1.3e-47 162.5 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KKK16930.1 - 1.4e-05 25.4 0.3 1.5 9.3 0.0 3.7 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.1 KKK16930.1 - 0.00071 19.1 0.1 0.0056 16.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal MHC_I_C PF06623.6 KKK16930.1 - 0.075 12.5 1.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 MHC_I C-terminus Glyco_transf_15 PF01793.11 KKK16931.1 - 3.7e-135 450.1 6.8 4.4e-135 449.8 4.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase COX5A PF02284.11 KKK16932.1 - 4.5e-29 100.5 0.0 4.9e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Spc97_Spc98 PF04130.8 KKK16933.1 - 3.9e-80 269.7 10.3 3.9e-80 269.7 7.2 1.7 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KKK16933.1 - 2.4e-07 29.2 0.1 8.3e-07 27.5 0.0 1.9 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 Sigma70_ner PF04546.8 KKK16933.1 - 0.0027 17.3 4.6 0.0067 16.0 3.2 1.6 1 0 0 1 1 1 1 Sigma-70, non-essential region TFIIA PF03153.8 KKK16933.1 - 0.0042 17.0 1.8 0.0063 16.4 1.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.5 KKK16933.1 - 0.012 15.8 8.1 0.031 14.4 5.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 KKK16933.1 - 0.25 10.5 8.5 0.37 10.0 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein BTV_NS2 PF04514.7 KKK16933.1 - 0.27 10.0 3.7 0.54 9.0 2.6 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TRAP_alpha PF03896.11 KKK16933.1 - 0.27 10.1 2.8 0.6 9.0 1.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 KKK16933.1 - 0.55 8.9 13.0 0.87 8.2 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Lon_C PF05362.8 KKK16950.1 - 1.3e-64 217.3 0.0 2.1e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KKK16950.1 - 7.7e-37 126.9 0.0 1.8e-36 125.7 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KKK16950.1 - 6.3e-22 78.1 0.0 1.5e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KKK16950.1 - 1.5e-07 30.9 0.0 4.3e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KKK16950.1 - 2.4e-07 30.5 0.0 4.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KKK16950.1 - 1.9e-06 27.9 0.0 5.6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KKK16950.1 - 7.2e-06 26.1 0.1 0.00012 22.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK16950.1 - 8.1e-06 26.6 0.0 3.5e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 KKK16950.1 - 3e-05 22.9 0.2 6.6e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.1 KKK16950.1 - 5e-05 23.3 0.0 0.00022 21.2 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KKK16950.1 - 0.00031 19.8 0.0 0.0014 17.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KKK16950.1 - 0.0007 19.9 1.9 0.0026 18.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KKK16950.1 - 0.0015 18.4 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 KKK16950.1 - 0.0089 15.5 0.0 0.046 13.2 0.0 2.1 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 KKK16950.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 KKK16950.1 - 0.018 13.7 0.2 0.21 10.2 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus NTPase_1 PF03266.10 KKK16950.1 - 0.024 14.3 0.2 0.26 11.0 0.0 2.5 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.17 KKK16950.1 - 0.03 14.4 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 KKK16950.1 - 0.038 13.1 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KKK16950.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KKK16950.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KKK16950.1 - 0.071 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KKK16950.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KKK16950.1 - 0.12 12.6 1.6 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 KKK16950.1 - 0.14 11.8 0.0 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain BRO1 PF03097.13 KKK16951.1 - 2e-123 411.9 1.3 2.2e-123 411.7 0.1 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KKK16951.1 - 2.8e-79 266.1 21.5 2.7e-62 210.3 4.1 2.6 2 1 1 3 3 3 2 ALIX V-shaped domain binding to HIV CTDII PF01556.13 KKK16951.1 - 3e-27 94.3 0.7 1.5e-20 72.8 0.1 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KKK16951.1 - 2.4e-23 81.6 1.1 8.2e-23 79.9 0.7 2.0 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KKK16951.1 - 6.4e-11 42.1 20.3 1.2e-10 41.2 14.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Pkinase PF00069.20 KKK16952.1 - 2e-10 40.2 0.0 3.7e-09 36.1 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16952.1 - 1e-09 37.8 0.0 7.5e-09 35.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase cobW PF02492.14 KKK16953.1 - 1.2e-45 155.1 0.1 1.6e-45 154.7 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KKK16953.1 - 9.3e-06 25.2 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 KKK16953.1 - 0.0014 18.4 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KKK16953.1 - 0.0036 17.3 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK16953.1 - 0.0045 17.1 0.3 0.17 12.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain Septin PF00735.13 KKK16953.1 - 0.0074 15.3 0.3 0.84 8.5 0.0 2.1 2 0 0 2 2 2 1 Septin AAA_18 PF13238.1 KKK16953.1 - 0.014 15.6 0.5 0.051 13.8 0.1 2.0 2 1 1 3 3 2 0 AAA domain ArgK PF03308.11 KKK16953.1 - 0.019 13.7 0.3 1.1 8.0 0.0 2.6 3 0 0 3 3 3 0 ArgK protein MMR_HSR1 PF01926.18 KKK16953.1 - 0.023 14.6 0.1 0.054 13.4 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KKK16953.1 - 0.04 14.2 0.4 0.3 11.3 0.0 2.4 3 0 0 3 3 3 0 ABC transporter T2SE PF00437.15 KKK16953.1 - 0.043 12.7 0.0 0.084 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KKK16953.1 - 0.048 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KKK16953.1 - 0.079 12.3 0.1 7.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KKK16953.1 - 0.085 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KKK16953.1 - 0.086 12.6 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 KKK16953.1 - 0.091 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KKK16953.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 KKK16953.1 - 0.092 13.2 0.3 0.4 11.1 0.0 2.1 2 1 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 KKK16953.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KKK16953.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mob1_phocein PF03637.12 KKK16954.1 - 5e-26 91.4 0.0 7.9e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Diphthamide_syn PF01866.12 KKK16955.1 - 1.6e-52 178.6 0.0 3.8e-52 177.4 0.0 1.5 2 0 0 2 2 2 1 Putative diphthamide synthesis protein Nucleoplasmin PF03066.10 KKK16955.1 - 0.27 10.7 7.3 0.56 9.7 5.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin VID27 PF08553.5 KKK16955.1 - 3 5.9 6.6 4.3 5.4 4.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 KKK16955.1 - 3.1 5.6 6.0 4.4 5.1 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 KKK16955.1 - 3.7 6.6 8.7 6.4 5.8 6.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 KKK16955.1 - 3.9 5.8 8.7 5.6 5.3 6.1 1.1 1 0 0 1 1 1 0 Daxx Family CS PF04969.11 KKK16957.1 - 1.3e-18 67.3 0.0 2.6e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 CS domain Cutinase PF01083.17 KKK16958.1 - 4.8e-52 176.2 0.0 5.4e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KKK16958.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KKK16958.1 - 0.0092 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.3 KKK16958.1 - 0.048 13.0 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Methyltransf_6 PF03737.10 KKK16958.1 - 0.092 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Demethylmenaquinone methyltransferase Abhydrolase_2 PF02230.11 KKK16958.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Zn_clus PF00172.13 KKK16959.1 - 3.9e-10 39.4 10.1 6.9e-10 38.6 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Smr PF01713.16 KKK16960.1 - 1.6e-10 41.0 0.1 3.1e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 KKK16960.1 - 5.7e-10 39.0 9.0 9.9e-10 38.3 6.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 KKK16960.1 - 2.2e-07 30.2 0.0 4.7e-05 22.7 0.0 3.3 3 0 0 3 3 3 1 CUE domain zf-C2H2_2 PF12756.2 KKK16961.1 - 5.1e-39 132.4 10.8 1.4e-31 108.5 1.9 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KKK16961.1 - 4.2e-07 29.9 19.2 5.8e-07 29.4 3.8 4.4 4 1 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK16961.1 - 1.6e-05 24.8 4.5 1.6e-05 24.8 3.1 3.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-LYAR PF08790.6 KKK16961.1 - 0.0038 16.8 0.5 0.0038 16.8 0.3 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF2024 PF09630.5 KKK16961.1 - 0.047 13.3 3.7 4.4 7.0 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) zf-C2H2 PF00096.21 KKK16961.1 - 0.14 12.5 18.7 0.16 12.4 0.3 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KKK16961.1 - 0.17 11.8 7.5 1.9 8.5 0.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF21 PF01595.15 KKK16962.1 - 1.8e-31 108.8 0.3 3.3e-31 107.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KKK16962.1 - 6.3e-08 32.2 0.4 0.014 15.1 0.0 3.1 2 0 0 2 2 2 2 CBS domain SPT6_acidic PF14632.1 KKK16962.1 - 0.17 12.0 4.4 1.4 9.1 0.5 2.8 3 0 0 3 3 3 0 Acidic N-terminal SPT6 His_Phos_1 PF00300.17 KKK16963.1 - 2.4e-12 47.2 0.0 5.4e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1248 PF06852.7 KKK16963.1 - 0.089 12.0 0.1 0.21 10.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1248) HECT PF00632.20 KKK16964.1 - 2.4e-75 253.6 0.0 3.7e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RRF PF01765.14 KKK16965.1 - 0.031 13.7 2.7 0.05 13.0 1.9 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Rubella_E2 PF05749.6 KKK16965.1 - 0.11 11.7 7.4 0.21 10.8 5.1 1.4 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Peptidase_M20 PF01546.23 KKK16967.1 - 8.3e-23 80.8 0.0 1.7e-21 76.5 0.0 2.8 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KKK16967.1 - 1.4e-10 40.6 6.0 0.041 13.7 0.1 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat M20_dimer PF07687.9 KKK16967.1 - 1e-05 25.2 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KKK16967.1 - 0.0038 17.0 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M28 SpdB PF05122.8 KKK16967.1 - 0.036 14.0 0.5 0.036 14.0 0.3 2.1 2 0 0 2 2 2 0 Mobile element transfer protein PQQ_3 PF13570.1 KKK16967.1 - 0.039 14.2 0.8 12 6.2 0.0 4.1 3 0 0 3 3 3 0 PQQ-like domain Shisa PF13908.1 KKK16967.1 - 9.5 6.3 7.1 2.6 8.1 2.1 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF747 PF05346.6 KKK16968.1 - 1.7e-129 431.6 4.0 1.7e-129 431.6 2.7 1.7 2 0 0 2 2 2 1 Eukaryotic membrane protein family Cas_TM1802 PF09484.5 KKK16968.1 - 0.7 8.3 0.0 1 7.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) Pyr_redox_3 PF13738.1 KKK16969.1 - 1.7e-19 70.6 1.3 2.3e-10 40.8 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK16969.1 - 3.5e-13 48.5 2.5 1.2e-10 40.2 0.1 3.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK16969.1 - 5.4e-09 35.9 0.0 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KKK16969.1 - 4.9e-07 28.9 0.1 0.00051 19.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KKK16969.1 - 1.3e-06 28.4 0.0 0.00012 22.0 0.0 2.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK16969.1 - 5.1e-06 25.6 0.0 0.00018 20.5 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK16969.1 - 0.0011 18.1 0.1 0.0019 17.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KKK16969.1 - 0.0041 16.9 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KKK16969.1 - 0.01 14.7 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DUF4201 PF13870.1 KKK16970.1 - 0.098 12.0 0.2 0.098 12.0 0.1 4.8 2 2 1 4 4 4 0 Domain of unknown function (DUF4201) SBP_bac_11 PF13531.1 KKK16970.1 - 0.3 10.6 3.5 0.16 11.5 0.2 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein CCDC155 PF14662.1 KKK16970.1 - 2.9 7.4 46.1 0.011 15.3 5.0 4.4 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 DUF948 PF06103.6 KKK16970.1 - 4.6 7.1 8.2 13 5.7 0.1 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) MFS_1 PF07690.11 KKK16974.1 - 8.5e-36 123.3 22.8 1.2e-35 122.8 15.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SSP160 PF06933.6 KKK16975.1 - 7.6 4.3 8.6 11 3.8 6.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ELO PF01151.13 KKK16976.1 - 1e-86 290.3 5.2 1.2e-86 290.0 3.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Glyco_hydro_35 PF01301.14 KKK16977.1 - 3.4e-72 243.5 3.2 3.4e-72 243.5 2.2 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KKK16977.1 - 2.7e-69 232.2 0.4 5e-69 231.3 0.3 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KKK16977.1 - 2e-51 172.8 13.0 1.3e-27 96.2 1.4 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KKK16977.1 - 3e-27 93.8 0.0 6.6e-27 92.7 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 SKG6 PF08693.5 KKK16978.1 - 3.3e-06 26.2 1.9 9.4e-06 24.8 1.3 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KKK16978.1 - 4e-06 26.4 0.0 6.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3188 PF11384.3 KKK16978.1 - 0.0026 17.2 0.7 0.0045 16.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3188) TMEM154 PF15102.1 KKK16978.1 - 0.003 17.2 0.4 0.006 16.3 0.3 1.5 1 0 0 1 1 1 1 TMEM154 protein family RCR PF12273.3 KKK16978.1 - 0.023 15.2 7.0 0.023 15.2 4.9 2.5 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Adeno_E3_CR2 PF02439.10 KKK16978.1 - 0.034 13.6 0.1 0.06 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF912 PF06024.7 KKK16978.1 - 0.62 10.1 11.2 16 5.6 7.8 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mem_trans PF03547.13 KKK16978.1 - 1.4 7.0 0.0 1.4 7.0 0.0 2.0 1 1 0 2 2 2 0 Membrane transport protein Menin PF05053.8 KKK16978.1 - 7.9 4.5 6.8 10 4.1 4.7 1.2 1 0 0 1 1 1 0 Menin TAF4 PF05236.9 KKK16980.1 - 4.4e-19 68.7 0.5 3.1e-06 26.6 0.3 3.2 3 0 0 3 3 3 3 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 KKK16981.1 - 3.2e-76 255.4 0.2 1.1e-74 250.4 0.1 2.5 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term TruD PF01142.13 KKK16981.1 - 1.3e-47 162.2 0.0 3.1e-45 154.4 0.0 3.2 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Beta-Casp PF10996.3 KKK16981.1 - 2e-31 108.5 0.0 4.4e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KKK16981.1 - 3.6e-17 62.6 0.1 7.9e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK16981.1 - 9.3e-11 41.6 0.3 2.5e-10 40.2 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KKK16981.1 - 1.2e-06 28.2 0.1 2.5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KKK16981.1 - 0.00028 20.6 0.1 0.0009 18.9 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.20 KKK16982.1 - 3.5e-54 183.6 0.1 1e-53 182.1 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16982.1 - 4.4e-20 71.8 0.0 5.9e-19 68.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase AIG2_2 PF13772.1 KKK16983.1 - 0.0023 17.9 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 KKK16983.1 - 0.0051 17.2 0.0 0.0075 16.7 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family TGF_beta_GS PF08515.7 KKK16983.1 - 0.13 11.5 1.3 0.27 10.5 0.9 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Glyco_hydro_47 PF01532.15 KKK16984.1 - 3.8e-134 447.7 0.0 4.8e-134 447.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 EcoRII-C PF09019.6 KKK16984.1 - 0.29 10.9 0.0 0.51 10.1 0.0 1.3 1 0 0 1 1 1 0 EcoRII C terminal Pribosyltran PF00156.22 KKK16986.1 - 8.2e-16 57.8 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KKK16986.1 - 0.0037 16.4 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase TRAPP PF04051.11 KKK16987.1 - 7.2e-39 132.7 0.0 8.5e-39 132.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 KKK16987.1 - 0.13 12.0 1.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) WD40 PF00400.27 KKK16989.1 - 6.5e-61 200.1 6.2 6e-09 35.4 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KKK16989.1 - 1.6e-05 24.7 0.0 0.29 10.8 0.0 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KKK16989.1 - 2e-05 23.5 3.8 0.029 13.1 0.3 3.7 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 KKK16989.1 - 0.0065 15.9 0.3 7 6.0 0.0 3.2 2 1 1 3 3 3 1 PQQ-like domain Not3 PF04065.10 KKK16995.1 - 4.4e-98 327.2 18.9 6.1e-98 326.7 13.1 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KKK16995.1 - 7.8e-45 152.0 11.4 1.7e-44 150.9 7.9 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 KKK16995.1 - 0.0077 15.7 3.4 0.019 14.5 2.4 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 KKK16995.1 - 0.017 15.0 4.7 0.12 12.3 0.1 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.6 KKK16995.1 - 0.059 13.1 2.4 0.17 11.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.1 KKK16995.1 - 0.076 13.3 7.1 0.15 12.3 0.4 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin_2 PF14523.1 KKK16995.1 - 0.18 11.8 7.4 0.044 13.8 1.3 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Cob_adeno_trans PF01923.13 KKK16995.1 - 1.3 8.7 4.4 1.1 8.9 0.5 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Syntaxin PF00804.20 KKK16995.1 - 4 7.6 12.2 0.25 11.4 1.8 2.5 1 1 1 2 2 2 0 Syntaxin DUF904 PF06005.7 KKK16995.1 - 5.1 7.4 10.7 9.2 6.6 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) SlyX PF04102.7 KKK16995.1 - 8 6.9 9.9 2.5 8.5 0.5 4.0 3 1 1 4 4 4 0 SlyX Tyr_Deacylase PF02580.11 KKK16996.1 - 1.7e-44 151.3 0.0 2.2e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.16 KKK16997.1 - 2.3e-48 164.3 0.7 4.1e-48 163.5 0.5 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KKK16997.1 - 1e-10 41.1 4.3 3.6e-05 23.3 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KKK16997.1 - 3.7e-07 29.5 4.6 3.2e-05 23.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK16997.1 - 1.6e-06 27.4 4.6 1.1e-05 24.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK16997.1 - 8.6e-06 25.6 3.2 3.3e-05 23.7 1.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK16997.1 - 0.0013 19.1 0.9 0.0074 16.8 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK16997.1 - 0.014 15.1 3.7 0.041 13.6 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK16997.1 - 0.025 14.4 0.7 0.086 12.7 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK16997.1 - 0.22 12.2 5.6 1 10.1 2.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK16997.1 - 0.28 11.7 1.8 1.6 9.3 0.1 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK16997.1 - 0.5 10.7 4.8 1 9.7 2.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MIF4G PF02854.14 KKK16999.1 - 9.8e-25 87.1 0.2 2.4e-24 85.9 0.2 1.7 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KKK16999.1 - 2.8e-17 62.4 0.1 1.1e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.10 KKK17000.1 - 6.4e-26 90.1 0.2 8.4e-26 89.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Alb1 PF09135.6 KKK17000.1 - 0.96 10.0 7.9 1.3 9.7 5.5 1.2 1 0 0 1 1 1 0 Alb1 Inp1 PF12634.2 KKK17001.1 - 8.1e-35 119.6 0.0 1.7e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 KKK17002.1 - 3.1e-06 26.7 2.8 3.1e-06 26.7 2.0 3.5 2 2 1 3 3 3 1 Etoposide-induced protein 2.4 (EI24) FmdA_AmdA PF03069.10 KKK17003.1 - 3.2e-156 519.6 0.0 3.7e-156 519.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family FAD_binding_3 PF01494.14 KKK17004.1 - 1e-17 64.2 2.0 8e-17 61.3 1.4 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK17004.1 - 8.3e-07 28.9 0.3 2.1e-06 27.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK17004.1 - 0.0078 15.1 1.8 0.029 13.2 0.6 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KKK17004.1 - 0.014 15.4 0.1 0.035 14.1 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK17004.1 - 0.016 15.0 0.7 0.045 13.6 0.5 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK17004.1 - 0.018 15.4 0.1 0.13 12.7 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KKK17004.1 - 0.032 13.5 0.2 0.09 12.1 0.2 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 KKK17004.1 - 0.033 13.0 0.5 0.033 13.0 0.3 1.9 2 1 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK17004.1 - 0.056 12.5 0.1 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Glyoxalase_2 PF12681.2 KKK17024.1 - 6.4e-07 29.9 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain Rick_17kDa_Anti PF05433.10 KKK17024.1 - 0.011 15.3 0.8 0.011 15.3 0.6 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 KKK17024.1 - 0.73 9.5 8.0 0.055 13.1 1.0 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 KKK17024.1 - 0.78 9.4 7.3 0.037 13.6 0.8 1.9 2 0 0 2 2 2 0 Glycine zipper XPG_I PF00867.13 KKK17025.1 - 3.5e-31 107.1 0.4 1e-30 105.6 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KKK17025.1 - 8.3e-25 86.9 0.5 4.6e-24 84.5 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KKK17025.1 - 0.00018 21.6 0.0 0.00018 21.6 0.0 2.4 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Fungal_trans PF04082.13 KKK17026.1 - 7.5e-11 41.3 1.3 1.5e-10 40.4 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17026.1 - 3.1e-09 36.5 8.1 5e-09 35.9 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_U40 PF10464.4 KKK17026.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase U40 Acyl-CoA_dh_1 PF00441.19 KKK17027.1 - 5.5e-25 88.2 0.3 9e-25 87.5 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KKK17027.1 - 2.6e-23 82.7 0.1 5.2e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KKK17027.1 - 5.1e-16 57.9 0.0 1.1e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KKK17027.1 - 5.3e-09 36.4 0.3 1.1e-08 35.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.21 KKK17028.1 - 1.2e-42 144.7 0.1 1.3e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK17028.1 - 3.8e-05 23.4 0.0 4.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KKK17028.1 - 0.0022 17.8 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KKK17028.1 - 0.014 15.0 0.2 0.023 14.3 0.1 1.3 1 1 0 1 1 1 0 UEV domain CENP-R PF06729.7 KKK17029.1 - 0.0071 16.0 2.4 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Kinetochore component, CENP-R Linker_histone PF00538.14 KKK17030.1 - 2.6e-22 78.6 0.4 2.6e-22 78.6 0.3 1.7 2 0 0 2 2 2 1 linker histone H1 and H5 family KAR9 PF08580.5 KKK17030.1 - 3.9 5.6 15.9 4.4 5.4 11.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ribosomal_S9 PF00380.14 KKK17033.1 - 3.7e-26 91.7 0.3 4.1e-26 91.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 LON PF02190.11 KKK17034.1 - 1.6e-24 86.7 0.0 2.2e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-RING_2 PF13639.1 KKK17034.1 - 9.1e-11 41.4 16.5 1.1e-08 34.7 6.3 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 KKK17034.1 - 1e-10 41.4 17.9 2.1e-07 30.8 6.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK17034.1 - 7.7e-10 38.3 15.1 6.2e-07 29.0 4.8 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK17034.1 - 8.6e-10 38.1 10.7 3.6e-08 32.9 3.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK17034.1 - 1.5e-08 34.1 13.1 2.2e-06 27.2 5.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KKK17034.1 - 7.7e-05 22.4 7.2 7.7e-05 22.4 5.0 3.0 3 1 0 3 3 2 2 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 KKK17034.1 - 0.0012 18.3 5.8 0.0012 18.3 4.0 1.9 2 0 0 2 2 2 1 P-11 zinc finger zf-RING_4 PF14570.1 KKK17034.1 - 0.0082 15.6 6.0 0.038 13.5 3.1 2.6 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KKK17034.1 - 0.011 15.3 2.5 0.011 15.3 1.8 3.3 3 0 0 3 3 3 0 RING-type zinc-finger U-box PF04564.10 KKK17034.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 U-box domain Cut8_M PF14483.1 KKK17034.1 - 0.038 13.7 0.9 0.075 12.8 0.2 1.8 2 0 0 2 2 2 0 Cut8 dimerisation domain zf-rbx1 PF12678.2 KKK17034.1 - 0.039 14.0 2.4 0.1 12.7 1.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger RRM_6 PF14259.1 KKK17035.1 - 1.1e-05 25.2 0.0 0.064 13.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L23 PF00276.15 KKK17035.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L23 Peptidase_M19 PF01244.16 KKK17037.1 - 2.5e-103 345.3 0.0 3.2e-103 345.0 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) WD40 PF00400.27 KKK17038.1 - 6.8e-68 222.3 21.3 2.5e-11 42.9 0.4 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KKK17038.1 - 9.6e-06 24.0 3.7 0.00083 17.6 0.4 3.4 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KKK17038.1 - 0.00095 18.0 0.4 6.7 5.3 0.0 3.2 2 1 1 3 3 3 3 Nup133 N terminal like Hira PF07569.6 KKK17038.1 - 0.038 13.2 0.2 6.7 5.8 0.1 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split SlyX PF04102.7 KKK17038.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 SlyX Cytochrom_D1 PF02239.11 KKK17038.1 - 0.12 10.6 0.0 0.49 8.6 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain Glyco_transf_34 PF05637.7 KKK17039.1 - 6.3e-14 52.0 0.0 3e-09 36.7 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KKK17039.1 - 0.00067 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.11 KKK17039.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Sds3 PF08598.6 KKK17040.1 - 0.0097 15.4 1.3 0.063 12.7 0.1 2.1 2 0 0 2 2 2 1 Sds3-like Ribonuc_2-5A PF06479.7 KKK17041.1 - 1.3e-41 141.4 0.0 2.2e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KKK17041.1 - 1.7e-41 142.1 0.0 2.7e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17041.1 - 1.5e-19 70.1 0.0 4.2e-19 68.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 KKK17041.1 - 0.00021 20.6 0.0 0.077 12.5 0.0 2.9 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 KKK17041.1 - 0.017 14.6 0.1 0.32 10.4 0.1 2.2 1 1 2 3 3 3 0 PQQ-like domain Kdo PF06293.9 KKK17041.1 - 0.062 12.3 0.3 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 KKK17042.1 - 1.2e-79 268.0 0.0 1.3e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IBR PF01485.16 KKK17049.1 - 3.3e-08 33.2 7.0 9.6e-07 28.5 1.6 4.5 5 0 0 5 5 5 3 IBR domain Cation_efflux PF01545.16 KKK17050.1 - 2.2e-26 92.5 4.6 2.9e-26 92.2 3.2 1.1 1 0 0 1 1 1 1 Cation efflux family ATG16 PF08614.6 KKK17050.1 - 0.36 10.6 3.3 0.49 10.1 1.9 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Aminotran_3 PF00202.16 KKK17051.1 - 1.5e-96 323.1 0.0 1.9e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KKK17051.1 - 5.7e-05 22.2 0.0 8.6e-05 21.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Lactonase PF10282.4 KKK17052.1 - 1.7e-23 83.2 0.0 2.1e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Metallophos PF00149.23 KKK17053.1 - 1.8e-09 37.3 0.5 5.9e-09 35.6 0.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SR-25 PF10500.4 KKK17053.1 - 2 7.8 9.9 0.18 11.2 2.8 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein 14-3-3 PF00244.15 KKK17055.1 - 4.5e-11 42.2 0.4 9e-11 41.3 0.1 1.5 2 0 0 2 2 2 1 14-3-3 protein DUF1674 PF07896.7 KKK17056.1 - 7.5e-16 58.0 2.8 7.5e-16 58.0 1.9 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) DUF836 PF05768.9 KKK17057.1 - 8.3e-13 48.4 0.0 1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 KKK17057.1 - 0.043 14.0 0.1 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.19 KKK17057.1 - 0.062 13.2 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin CHORD PF04968.7 KKK17058.1 - 2.2e-52 175.1 20.0 4.4e-27 94.1 4.2 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 KKK17058.1 - 1.9e-15 57.1 0.1 2.9e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 CS domain Pheromone PF08015.6 KKK17058.1 - 0.017 15.9 0.5 0.04 14.7 0.4 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone LSM PF01423.17 KKK17059.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF2763 PF10961.3 KKK17059.1 - 0.097 13.0 11.8 0.13 12.6 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Methyltransf_26 PF13659.1 KKK17060.1 - 3.1e-15 56.2 0.0 5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK17060.1 - 5.4e-05 22.6 0.3 0.086 12.2 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.7 KKK17060.1 - 0.00067 20.0 5.8 0.00099 19.5 2.4 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK17060.1 - 0.07 12.8 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 KKK17060.1 - 0.12 11.3 0.3 0.43 9.6 0.0 1.7 1 1 1 2 2 2 0 Putative methyltransferase Methyltransf_25 PF13649.1 KKK17060.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Phos_pyr_kin PF08543.7 KKK17061.1 - 7.6e-84 280.7 0.3 1e-83 280.3 0.2 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KKK17061.1 - 1.2e-53 181.9 0.1 1.7e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KKK17061.1 - 1e-06 28.1 0.2 1.6e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 KKK17061.1 - 0.00022 20.4 1.0 0.0066 15.6 0.0 2.2 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 KKK17061.1 - 0.0011 18.3 2.4 0.0051 16.1 1.7 2.1 1 1 0 1 1 1 1 Carbohydrate kinase DNA_pol_B PF00136.16 KKK17062.1 - 8.5e-115 384.1 2.5 1.4e-114 383.4 1.7 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KKK17062.1 - 2e-67 226.2 1.1 3.4e-67 225.4 0.8 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KKK17062.1 - 2.5e-37 128.4 0.0 5.2e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KKK17062.1 - 1.1e-24 85.9 8.4 1.1e-24 85.9 5.8 2.7 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal HsbA PF12296.3 KKK17063.1 - 4.3e-14 52.4 8.5 4.3e-12 45.9 1.0 2.8 2 1 1 3 3 3 2 Hydrophobic surface binding protein A CitG PF01874.11 KKK17063.1 - 0.012 14.7 0.5 0.014 14.5 0.4 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase DEAD PF00270.24 KKK17064.1 - 1.2e-44 151.7 0.0 1.6e-42 144.9 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK17064.1 - 9.6e-28 95.8 0.0 2e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK17064.1 - 0.00065 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KKK17064.1 - 0.0023 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2443 PF10398.4 KKK17064.1 - 0.022 14.5 0.2 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF1253 PF06862.7 KKK17064.1 - 0.061 11.7 0.0 0.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) POTRA_2 PF08479.6 KKK17064.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type Sugar_tr PF00083.19 KKK17065.1 - 2.2e-20 72.6 21.5 1.1e-18 67.1 14.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter RCC1 PF00415.13 KKK17066.1 - 3.3e-28 97.6 31.7 8.9e-08 32.2 0.1 8.5 6 3 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KKK17066.1 - 1e-22 79.1 23.0 6.6e-08 31.9 0.1 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Ribosomal_60s PF00428.14 KKK17066.1 - 3.6 8.0 8.0 8.1 6.9 5.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Rad9 PF04139.8 KKK17067.1 - 8.9e-60 201.9 2.8 1.1e-59 201.6 2.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 KKK17067.1 - 4.3e-06 25.7 2.9 6.4e-05 21.8 1.7 2.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF2683 PF10884.3 KKK17067.1 - 0.017 15.0 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) LRR_4 PF12799.2 KKK17068.1 - 0.0001 21.7 4.8 0.9 9.2 0.2 5.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK17068.1 - 0.025 14.3 5.4 48 3.8 0.1 5.6 6 2 0 6 6 6 0 Leucine rich repeat GRASP55_65 PF04495.9 KKK17069.1 - 5.8e-40 136.4 0.0 3.1e-37 127.6 0.0 2.2 1 1 0 2 2 2 2 GRASP55/65 PDZ-like domain ApoO PF09769.4 KKK17070.1 - 9.4e-52 174.9 0.2 6.9e-51 172.0 0.1 1.9 2 0 0 2 2 2 1 Apolipoprotein O 4HBT_3 PF13622.1 KKK17070.1 - 0.029 14.1 2.2 0.033 13.9 1.5 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Mito_fiss_reg PF05308.6 KKK17070.1 - 2.7 7.2 10.6 4.1 6.7 7.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Peptidase_M3 PF01432.15 KKK17071.1 - 7e-115 384.6 0.0 9.3e-115 384.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KKK17071.1 - 0.098 12.0 0.2 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like TPR_MLP1_2 PF07926.7 KKK17072.1 - 6.2e-05 22.7 1.8 6.2e-05 22.7 1.2 10.5 2 2 8 10 10 10 4 TPR/MLP1/MLP2-like protein Filament PF00038.16 KKK17072.1 - 0.00015 21.3 172.2 0.0095 15.4 10.8 8.8 1 1 7 8 8 8 4 Intermediate filament protein Apolipoprotein PF01442.13 KKK17072.1 - 0.00051 19.6 32.0 0.00051 19.6 22.2 6.9 1 1 5 6 6 6 1 Apolipoprotein A1/A4/E domain Spc7 PF08317.6 KKK17072.1 - 0.0017 17.0 16.7 0.0017 17.0 11.6 8.3 1 1 8 9 9 9 4 Spc7 kinetochore protein IncA PF04156.9 KKK17072.1 - 0.0034 16.9 13.9 0.0034 16.9 9.6 8.7 1 1 7 8 8 8 1 IncA protein Tropomyosin_1 PF12718.2 KKK17072.1 - 0.0069 16.2 20.3 0.0069 16.2 14.0 9.5 1 1 6 8 8 8 2 Tropomyosin like Fib_alpha PF08702.5 KKK17072.1 - 0.0074 16.4 11.2 0.0074 16.4 7.8 9.8 1 1 9 11 11 11 3 Fibrinogen alpha/beta chain family Pkinase PF00069.20 KKK17073.1 - 7.5e-46 156.3 0.1 2.9e-23 82.3 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain FKBP_C PF00254.23 KKK17073.1 - 1.2e-30 105.3 0.0 2.5e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase_Tyr PF07714.12 KKK17073.1 - 8.3e-19 67.6 0.0 1e-10 41.1 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KKK17073.1 - 0.0002 21.2 0.5 0.00048 19.9 0.4 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3591 PF12157.3 KKK17074.1 - 1.8e-196 652.9 0.0 2.3e-196 652.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KKK17074.1 - 0.0034 17.0 1.1 0.0078 15.8 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KKK17074.1 - 0.015 15.2 0.9 0.025 14.5 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_15 PF09445.5 KKK17075.1 - 5.1e-51 172.4 0.0 6.4e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 KKK17075.1 - 1.4e-12 47.5 0.0 1.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KKK17075.1 - 1.7e-09 37.7 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KKK17075.1 - 1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 KKK17075.1 - 1.4e-06 28.8 0.0 1.9e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KKK17075.1 - 2.2e-05 23.9 0.0 3.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 KKK17075.1 - 0.00021 20.9 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK17075.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DNA_methylase PF00145.12 KKK17075.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.5 1 1 0 1 1 1 0 C-5 cytosine-specific DNA methylase PrmA PF06325.8 KKK17075.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PTPA PF03095.10 KKK17076.1 - 3.2e-114 381.1 0.0 3.8e-114 380.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.8 KKK17077.1 - 3.8e-09 36.2 7.0 4.7e-09 35.9 4.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) SgrR_N PF12793.2 KKK17077.1 - 0.045 13.7 0.6 0.91 9.5 0.1 2.3 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term Vps26 PF03643.10 KKK17078.1 - 2.4e-130 433.2 0.4 2.8e-130 433.0 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KKK17078.1 - 0.0005 19.9 0.2 1.1 9.0 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 KKK17078.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Arrestin_C PF02752.17 KKK17078.1 - 0.043 13.9 0.1 0.23 11.5 0.0 2.2 1 1 1 2 2 2 0 Arrestin (or S-antigen), C-terminal domain 2-oxoacid_dh PF00198.18 KKK17079.1 - 7.1e-77 257.7 0.0 1e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KKK17079.1 - 2.5e-13 49.4 0.0 4.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KKK17079.1 - 3.3e-12 45.8 0.2 7.7e-12 44.6 0.2 1.6 1 0 0 1 1 1 1 e3 binding domain DUF605 PF04652.11 KKK17079.1 - 0.16 11.3 7.4 0.21 10.9 5.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF544 PF04424.8 KKK17080.1 - 6.9e-08 32.3 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF221 PF02714.10 KKK17081.1 - 4e-106 354.5 26.7 4.1e-106 354.5 13.2 2.5 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 KKK17081.1 - 7.1e-41 139.3 3.4 7.1e-41 139.3 2.4 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KKK17081.1 - 7.2e-27 93.1 0.7 1.7e-26 91.9 0.5 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KKK17081.1 - 6.7e-19 68.2 0.1 1.2e-18 67.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Aldo_ket_red PF00248.16 KKK17082.1 - 2.9e-25 88.6 0.0 5.4e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family ParD PF09386.5 KKK17082.1 - 0.15 12.2 0.0 0.7 10.0 0.0 2.0 1 1 0 1 1 1 0 Antitoxin ParD HSF_DNA-bind PF00447.12 KKK17083.1 - 2.6e-29 101.4 0.2 5e-29 100.5 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 KKK17083.1 - 0.005 16.6 2.4 0.074 12.8 0.1 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Ets PF00178.17 KKK17083.1 - 0.15 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Ets-domain Rab5-bind PF09311.6 KKK17083.1 - 0.23 11.3 4.5 1.2 8.9 1.5 2.3 2 0 0 2 2 2 0 Rabaptin-like protein Pro_isomerase PF00160.16 KKK17084.1 - 3.5e-38 131.2 0.0 6.9e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3431 PF11913.3 KKK17085.1 - 2.2e-89 298.7 0.2 3.4e-89 298.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SR-25 PF10500.4 KKK17085.1 - 0.011 15.2 4.7 0.015 14.8 3.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.13 KKK17085.1 - 0.037 12.9 4.1 0.056 12.3 2.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Homez PF11569.3 KKK17085.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez His_Phos_2 PF00328.17 KKK17086.1 - 4.9e-12 45.8 0.2 8.6e-11 41.7 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TraG-D_C PF12696.2 KKK17086.1 - 0.38 10.6 2.7 0.89 9.4 1.9 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Macoilin PF09726.4 KKK17086.1 - 0.67 8.1 2.6 0.92 7.7 1.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1517 PF07466.6 KKK17086.1 - 1.9 7.4 6.8 3.4 6.5 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) AAA PF00004.24 KKK17087.1 - 1.6e-16 60.6 0.0 2.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KKK17087.1 - 2.9e-16 59.2 0.0 6.5e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KKK17087.1 - 9.4e-13 48.1 0.1 2.5e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KKK17087.1 - 8.4e-12 44.5 0.0 6.3e-10 38.3 0.0 2.5 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KKK17087.1 - 3.1e-07 29.6 0.1 1.1e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KKK17087.1 - 3.2e-07 30.5 0.2 5.5e-06 26.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK17087.1 - 1.4e-06 27.9 0.1 3.9e-06 26.5 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 KKK17087.1 - 2.1e-06 27.8 0.1 2.9e-05 24.1 0.1 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 KKK17087.1 - 2.3e-06 27.3 0.2 0.00013 21.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 KKK17087.1 - 2e-05 24.1 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 KKK17087.1 - 2.4e-05 24.0 0.1 0.00011 21.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KKK17087.1 - 4.1e-05 23.4 0.0 0.00012 22.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 KKK17087.1 - 4.1e-05 22.6 0.0 6.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 KKK17087.1 - 5.3e-05 22.8 0.0 9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KKK17087.1 - 9.1e-05 21.3 0.0 0.23 10.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_3 PF07726.6 KKK17087.1 - 0.00015 21.4 0.3 0.00046 19.7 0.1 2.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KKK17087.1 - 0.0006 19.1 0.0 0.43 9.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 KKK17087.1 - 0.00062 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KKK17087.1 - 0.00097 18.1 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KKK17087.1 - 0.0024 17.3 0.1 0.04 13.3 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 KKK17087.1 - 0.004 16.5 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 KKK17087.1 - 0.0053 16.7 0.0 0.0094 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK17087.1 - 0.0065 16.7 0.0 0.015 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KKK17087.1 - 0.0076 15.4 0.1 0.088 11.9 0.1 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 KKK17087.1 - 0.0079 16.0 0.0 0.25 11.1 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KKK17087.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 KKK17087.1 - 0.011 15.2 0.0 0.025 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KKK17087.1 - 0.028 15.2 0.0 0.079 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KKK17087.1 - 0.035 13.5 0.0 0.089 12.2 0.0 1.7 2 0 0 2 2 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KKK17087.1 - 0.047 13.1 0.3 3.4 7.0 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KKK17087.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 KKK17087.1 - 0.062 12.0 0.0 4.6 5.9 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain NACHT PF05729.7 KKK17087.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.17 KKK17087.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 KKK17087.1 - 0.12 11.9 0.0 0.3 10.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase P21-Arc PF04062.9 KKK17088.1 - 9e-79 263.2 0.0 1e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.8 KKK17089.1 - 2.1e-105 352.1 0.0 2.6e-105 351.8 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Nol1_Nop2_Fmu PF01189.12 KKK17090.1 - 6.6e-93 311.1 0.0 1.1e-92 310.4 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KKK17090.1 - 0.0019 18.2 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DDE_Tnp_1_6 PF13751.1 KKK17090.1 - 0.41 10.6 5.1 1.1 9.2 3.6 1.7 1 0 0 1 1 1 0 Transposase DDE domain G0-G1_switch_2 PF15103.1 KKK17090.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.0 3 1 1 4 4 4 0 G0/G1 switch protein 2 vMSA PF00695.14 KKK17090.1 - 9.9 5.2 9.3 16 4.5 6.5 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Blt1 PF12754.2 KKK17091.1 - 2.6e-61 207.9 0.0 3.1e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Cell-cycle control medial ring component Striatin PF08232.7 KKK17092.1 - 1.1e-44 152.0 9.0 1.1e-44 152.0 6.2 2.3 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 KKK17092.1 - 5.4e-30 102.1 15.0 3.7e-06 26.5 0.0 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KKK17092.1 - 0.0036 17.0 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KKK17092.1 - 0.064 11.5 0.0 0.15 10.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain AAA_23 PF13476.1 KKK17092.1 - 5.2 7.3 10.1 9.7 6.4 7.0 1.4 1 0 0 1 1 1 0 AAA domain PIG-P PF08510.7 KKK17093.1 - 1.2e-43 147.7 1.5 2e-43 147.0 0.1 1.9 2 0 0 2 2 2 1 PIG-P MORN PF02493.15 KKK17094.1 - 1.5e-13 49.5 25.0 3.3e-05 23.3 0.3 4.6 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.1 KKK17094.1 - 6.7e-12 44.8 9.7 1.1e-11 44.1 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 KKK17094.1 - 1.6e-09 37.3 0.0 3.8e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 KKK17094.1 - 0.0004 19.6 0.0 0.00088 18.5 0.0 1.5 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C3HC4_2 PF13923.1 KKK17094.1 - 0.014 15.3 11.7 0.031 14.2 8.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF605 PF04652.11 KKK17094.1 - 0.42 9.9 34.9 0.21 10.9 9.8 2.3 2 0 0 2 2 2 0 Vta1 like Tetraspannin PF00335.15 KKK17095.1 - 0.029 13.6 0.2 0.037 13.2 0.2 1.2 1 0 0 1 1 1 0 Tetraspanin family Sporozoite_P67 PF05642.6 KKK17095.1 - 0.032 12.0 11.2 0.045 11.6 7.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1675 PF07897.6 KKK17095.1 - 1 9.1 8.8 1.3 8.7 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Macoilin PF09726.4 KKK17095.1 - 1.3 7.2 14.6 1.5 7.0 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 KKK17095.1 - 1.6 8.0 11.5 1.9 7.7 8.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF515 PF04415.7 KKK17095.1 - 2.3 6.3 19.6 3.1 5.9 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Abhydro_lipase PF04083.11 KKK17096.1 - 6.4e-22 76.6 0.6 1.5e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KKK17096.1 - 2.7e-08 33.9 3.0 3e-08 33.8 1.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK17096.1 - 3.3e-05 23.6 0.0 7.3e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK17096.1 - 0.0026 17.3 0.1 0.0058 16.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Sugar_tr PF00083.19 KKK17098.1 - 5.1e-127 424.1 24.9 5.9e-127 423.9 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK17098.1 - 4.3e-24 84.8 55.0 3.6e-21 75.2 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MSP1b PF03429.8 KKK17098.1 - 0.11 10.4 0.3 0.15 9.8 0.2 1.1 1 0 0 1 1 1 0 Major surface protein 1B Metallophos PF00149.23 KKK17099.1 - 1e-05 25.0 2.3 0.00049 19.5 1.2 2.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase AChE_tetra PF08674.5 KKK17099.1 - 0.078 12.5 1.8 0.2 11.2 1.3 1.6 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain MFS_1 PF07690.11 KKK17100.1 - 2.9e-33 115.0 41.7 2.9e-33 115.0 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 4HBT PF03061.17 KKK17101.1 - 8.3e-09 35.4 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily HATPase_c PF02518.21 KKK17102.1 - 5.6e-30 103.3 0.0 1.4e-29 101.9 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK17102.1 - 1.5e-24 86.1 1.3 2.5e-24 85.4 0.3 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KKK17102.1 - 5.3e-14 51.9 0.0 1.6e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KKK17102.1 - 0.00025 21.1 1.3 0.00025 21.1 0.9 2.9 2 1 0 2 2 2 1 HAMP domain LSM PF01423.17 KKK17103.1 - 1.4e-18 66.2 0.2 1.7e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SIR2 PF02146.12 KKK17104.1 - 2.6e-14 53.3 0.0 8e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KKK17104.1 - 0.06 13.0 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain AgrD PF05931.6 KKK17104.1 - 0.064 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Staphylococcal AgrD protein O-FucT PF10250.4 KKK17105.1 - 0.046 12.8 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Glyco_hydro_18 PF00704.23 KKK17106.1 - 2e-94 316.8 5.2 2.4e-94 316.6 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.20 KKK17107.1 - 1.3e-58 198.2 0.0 1.8e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17107.1 - 3.5e-31 108.2 0.0 4.4e-30 104.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KKK17107.1 - 0.045 12.5 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Snf7 PF03357.16 KKK17108.1 - 0.00076 18.9 1.4 0.00095 18.5 0.9 1.2 1 0 0 1 1 1 1 Snf7 DUF4157 PF13699.1 KKK17108.1 - 0.069 13.2 0.8 0.19 11.9 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) DUF1654 PF07867.6 KKK17108.1 - 0.078 12.3 0.3 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) ThiS PF02597.15 KKK17108.1 - 0.079 13.3 1.1 0.13 12.7 0.2 1.8 2 0 0 2 2 2 0 ThiS family zf-C2H2 PF00096.21 KKK17115.1 - 2.2e-06 27.6 24.8 0.00034 20.7 0.9 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK17115.1 - 7.3e-05 22.8 24.7 0.0026 17.9 0.9 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-BED PF02892.10 KKK17115.1 - 0.16 11.7 1.7 0.39 10.5 1.2 1.6 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.7 KKK17115.1 - 0.34 11.0 5.8 2 8.5 1.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Hexapep PF00132.19 KKK17124.1 - 1.1e-07 31.0 5.5 0.00014 21.2 2.0 3.6 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK17124.1 - 1.2e-05 24.7 0.8 3.2e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KKK17124.1 - 0.054 12.0 0.0 0.065 11.7 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase MOSC_N PF03476.11 KKK17125.1 - 1.9e-20 72.7 0.0 2.7e-19 69.0 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KKK17125.1 - 2e-06 27.3 0.1 7.3e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 MOSC domain Ribosomal_S28e PF01200.13 KKK17146.1 - 1.3e-32 111.3 3.2 1.4e-32 111.2 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e GAS2 PF02187.12 KKK17147.1 - 0.00024 20.7 0.1 0.00047 19.8 0.1 1.3 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.7 KKK17148.1 - 1.2e-111 372.3 0.0 1.4e-111 372.1 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein DUF4552 PF15089.1 KKK17148.1 - 0.031 13.1 0.3 0.045 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) APS-reductase_C PF12139.3 KKK17148.1 - 0.052 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit DUF1777 PF08648.7 KKK17149.1 - 8.2e-23 81.0 75.9 5.7e-22 78.3 48.8 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) Sec16_C PF12931.2 KKK17150.1 - 4.4e-102 341.6 0.0 6e-102 341.2 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 KKK17150.1 - 3.4e-64 217.1 22.2 3.4e-64 217.1 15.4 3.4 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 KKK17150.1 - 7.3e-33 113.0 0.0 1.5e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region TPR_16 PF13432.1 KKK17150.1 - 0.016 15.8 10.8 1.7 9.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MMtag PF10159.4 KKK17151.1 - 9.6e-34 115.2 4.8 9.6e-34 115.2 3.4 2.5 2 1 0 2 2 2 1 Kinase phosphorylation protein Glyco_hydro_63 PF03200.11 KKK17152.1 - 2.7e-241 802.8 0.0 1.5e-240 800.3 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase DAO PF01266.19 KKK17152.1 - 5.7e-58 196.5 0.6 1e-57 195.7 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK17152.1 - 4.8e-06 26.5 0.2 1.3e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trehalase PF01204.13 KKK17152.1 - 0.0018 16.9 0.3 0.0035 16.0 0.2 1.4 1 0 0 1 1 1 1 Trehalase Trp_halogenase PF04820.9 KKK17152.1 - 0.004 15.8 0.1 0.03 12.9 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KKK17152.1 - 0.0054 16.6 0.6 1.1 9.0 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK17152.1 - 0.022 13.6 0.2 0.33 9.7 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 KKK17152.1 - 0.034 14.5 0.8 0.083 13.3 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Bac_rhamnosid PF05592.6 KKK17152.1 - 0.038 12.1 0.0 0.065 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase CRT10 PF08728.5 KKK17153.1 - 1.1e-23 83.1 0.0 1e-14 53.5 0.0 2.3 2 0 0 2 2 2 2 CRT10 SR-25 PF10500.4 KKK17153.1 - 1.1 8.6 10.9 2 7.8 7.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 KKK17153.1 - 1.5 8.8 6.4 2.5 8.1 3.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PTPLA PF04387.9 KKK17158.1 - 6.8e-54 181.7 1.8 1.1e-53 181.0 1.2 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.4 KKK17159.1 - 4.2e-17 62.6 15.9 6.9e-17 62.0 6.0 2.7 2 1 0 2 2 2 2 Alpha and gamma adaptin binding protein p34 MOR2-PAG1_N PF14222.1 KKK17188.1 - 2.2e-225 749.5 0.0 3.6e-225 748.8 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KKK17188.1 - 9.6e-96 320.5 0.0 2.4e-95 319.2 0.0 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KKK17188.1 - 2.8e-37 127.9 13.3 3e-13 48.3 0.4 3.9 2 1 1 3 3 3 3 Cell morphogenesis central region MMS1_N PF10433.4 KKK17189.1 - 6.5e-92 308.2 0.0 8.9e-92 307.8 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KKK17189.1 - 2.6e-75 253.4 0.0 6.1e-72 242.4 0.0 3.9 4 0 0 4 4 4 2 CPSF A subunit region FAD_binding_1 PF00667.15 KKK17190.1 - 9e-62 208.3 0.0 1.4e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KKK17190.1 - 1.4e-33 115.9 2.5 2.9e-33 114.8 1.8 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KKK17190.1 - 1.6e-22 80.1 0.0 1.4e-21 77.1 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KKK17190.1 - 0.0077 16.2 0.0 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin domain CENP-S PF15630.1 KKK17191.1 - 2.4e-34 117.3 0.0 2.9e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KKK17191.1 - 4.4e-06 26.2 0.0 5.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KKK17191.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TAF PF02969.12 KKK17191.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.6 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) PGA2 PF07543.7 KKK17192.1 - 1e-46 158.2 4.4 1.3e-46 157.9 3.1 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 EST1 PF10374.4 KKK17192.1 - 0.0031 17.5 0.5 0.0046 16.9 0.0 1.4 2 0 0 2 2 2 1 Telomerase activating protein Est1 Folate_carrier PF01770.13 KKK17192.1 - 0.012 14.1 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier BLVR PF06375.6 KKK17192.1 - 0.67 9.7 11.8 0.05 13.4 0.8 2.1 1 1 1 2 2 2 0 Bovine leukaemia virus receptor (BLVR) MARVEL PF01284.18 KKK17193.1 - 0.0018 18.1 18.0 0.0045 16.8 12.6 1.5 1 1 0 1 1 1 1 Membrane-associating domain RCR PF12273.3 KKK17193.1 - 0.006 17.1 1.7 0.013 16.0 0.1 2.0 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red SUR7 PF06687.7 KKK17193.1 - 0.098 12.2 4.3 3.7 7.0 0.4 2.1 1 1 1 2 2 2 0 SUR7/PalI family CPSase_L_D2 PF02786.12 KKK17194.1 - 1.1e-74 250.3 0.0 1.5e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KKK17194.1 - 6.5e-36 122.5 0.0 1.4e-35 121.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KKK17194.1 - 1.8e-33 114.9 0.0 4.1e-33 113.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KKK17194.1 - 7.4e-18 64.9 0.0 1.7e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KKK17194.1 - 5.9e-15 54.6 2.7 4.4e-14 51.8 1.3 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KKK17194.1 - 1.6e-11 43.5 0.0 3.3e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK17194.1 - 1.3e-10 41.0 0.0 2.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KKK17194.1 - 6.5e-08 32.1 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KKK17194.1 - 4.8e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KKK17194.1 - 0.00041 19.9 0.2 0.005 16.4 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like GARS_A PF01071.14 KKK17194.1 - 0.0013 18.3 0.1 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KKK17194.1 - 0.0063 15.9 0.0 0.027 13.9 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 KKK17194.1 - 0.03 13.4 0.0 0.075 12.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.14 KKK17194.1 - 0.038 13.6 0.1 0.092 12.4 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Acyl-CoA_dh_1 PF00441.19 KKK17196.1 - 3.7e-40 137.4 0.8 9.8e-40 136.0 0.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KKK17196.1 - 3.9e-32 111.1 0.2 7.6e-32 110.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KKK17196.1 - 8.9e-19 66.7 0.3 1.9e-18 65.6 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KKK17196.1 - 8.6e-14 51.9 0.2 1.7e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KKK17196.1 - 0.12 11.7 0.2 0.71 9.1 0.1 2.1 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Sulfotransfer_3 PF13469.1 KKK17197.1 - 0.056 14.3 0.0 0.088 13.7 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family Carboxyl_trans PF01039.17 KKK17198.1 - 3.1e-144 481.0 0.2 3.8e-144 480.6 0.2 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KKK17198.1 - 0.026 13.7 0.2 0.43 9.7 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) ketoacyl-synt PF00109.21 KKK17199.1 - 3.5e-71 239.6 0.0 6.7e-71 238.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK17199.1 - 1.6e-38 132.7 0.1 4.3e-38 131.4 0.1 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KKK17199.1 - 3.5e-35 120.4 3.1 8.8e-35 119.1 0.8 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KKK17199.1 - 1.6e-07 31.5 0.3 4.2e-07 30.1 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KKK17199.1 - 0.0079 15.2 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_2 PF00891.13 KKK17200.1 - 1.9e-29 102.5 0.0 3e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase p450 PF00067.17 KKK17201.1 - 1.4e-22 79.8 0.1 2e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3991 PF13154.1 KKK17201.1 - 0.01 15.9 0.1 0.043 14.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) Velvet PF11754.3 KKK17202.1 - 7.6e-79 264.0 0.0 9.7e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 Velvet factor Ribosomal_L13 PF00572.13 KKK17204.1 - 8.7e-36 122.8 0.0 1e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 OTU PF02338.14 KKK17205.1 - 1.6e-13 51.3 0.0 2.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KKK17205.1 - 0.041 13.2 0.0 0.087 12.1 0.0 1.4 1 1 0 1 1 1 0 Peptidase C65 Otubain Peptidase_C12 PF01088.16 KKK17206.1 - 2.6e-62 209.7 0.0 3.9e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 I-set PF07679.11 KKK17207.1 - 0.0098 15.7 0.2 1.3 8.9 0.0 4.0 5 0 0 5 5 5 1 Immunoglobulin I-set domain Oxysterol_BP PF01237.13 KKK17208.1 - 9.6e-47 159.1 0.0 1.3e-38 132.3 0.0 2.6 1 1 1 2 2 2 2 Oxysterol-binding protein Cys_Met_Meta_PP PF01053.15 KKK17209.1 - 3.7e-33 114.3 0.0 4.8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Nrap PF03813.9 KKK17210.1 - 0 1205.4 0.0 0 1205.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein MRP-L20 PF12824.2 KKK17211.1 - 1.7e-64 216.7 8.7 1.9e-64 216.5 6.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Mito_carr PF00153.22 KKK17212.1 - 7.8e-57 188.9 3.8 2.3e-23 81.7 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.24 KKK17213.1 - 1.7e-40 138.3 0.0 2.3e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK17213.1 - 8.3e-24 83.2 0.1 1.6e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK17213.1 - 0.082 12.7 0.0 0.82 9.4 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Peptidase_M20 PF01546.23 KKK17214.1 - 4.1e-30 104.7 0.0 6.8e-30 103.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KKK17214.1 - 1.7e-13 50.2 0.0 3.1e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain RF-1 PF00472.15 KKK17215.1 - 1.7e-34 118.0 1.4 1.7e-34 118.0 1.0 1.6 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 KKK17215.1 - 4.9e-29 100.3 0.0 9.3e-28 96.2 0.0 2.3 2 0 0 2 2 2 1 PCRF domain DUF3322 PF11795.3 KKK17215.1 - 0.023 14.3 2.1 0.43 10.2 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Pas_Saposin PF09016.5 KKK17215.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Pas factor saposin fold Cnd1_N PF12922.2 KKK17217.1 - 1.4e-59 200.5 0.0 3.5e-59 199.2 0.0 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KKK17217.1 - 5.1e-55 186.0 3.6 6.2e-50 169.5 0.1 3.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KKK17217.1 - 2.5e-13 50.1 4.7 2.6e-06 27.6 0.0 5.2 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KKK17217.1 - 1.3e-08 34.1 8.1 0.19 11.8 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.15 KKK17217.1 - 4.8e-07 28.4 7.1 0.016 13.5 0.2 4.1 3 2 0 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.1 KKK17217.1 - 8.7e-06 26.0 7.2 0.51 10.9 0.0 6.3 6 0 0 6 6 6 2 HEAT-like repeat DUF2435 PF10363.4 KKK17217.1 - 0.0023 17.8 0.0 1.3 8.9 0.0 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 KKK17217.1 - 0.036 13.0 5.2 0.071 12.0 0.7 3.4 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 KKK17217.1 - 0.046 13.6 3.0 13 5.8 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion mono-CXXC PF15626.1 KKK17217.1 - 1.6 8.7 3.9 34 4.4 0.9 2.7 2 0 0 2 2 2 0 single CXXC unit Pkinase PF00069.20 KKK17218.1 - 6.7e-42 143.4 0.0 2.3e-36 125.2 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17218.1 - 1.2e-09 37.6 0.0 0.00032 19.8 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KKK17218.1 - 0.011 15.4 0.4 1 9.0 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Bromodomain PF00439.20 KKK17219.1 - 1.6e-36 124.0 4.5 1.7e-19 69.5 0.1 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KKK17219.1 - 1.6e-17 63.3 1.3 3e-17 62.4 0.9 1.5 1 0 0 1 1 1 1 BAH domain DUF1353 PF07087.6 KKK17219.1 - 0.086 12.3 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) Nucleoplasmin PF03066.10 KKK17219.1 - 0.31 10.5 9.6 0.8 9.2 6.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KKK17219.1 - 3.7 7.8 13.5 14 5.9 9.4 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SMC_N PF02463.14 KKK17220.1 - 3.3e-21 75.5 20.3 8.7e-13 48.0 0.1 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KKK17220.1 - 8.1e-20 72.0 2.6 8.1e-20 72.0 1.8 4.7 2 2 1 4 4 4 1 AAA domain AAA_21 PF13304.1 KKK17220.1 - 1.2e-09 38.6 1.4 1.7e-05 24.9 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KKK17220.1 - 0.00011 21.6 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KKK17220.1 - 0.1 12.8 0.1 0.1 12.8 0.1 6.1 3 2 0 3 3 3 0 ABC transporter AAA_13 PF13166.1 KKK17220.1 - 1.8 6.9 72.2 0.18 10.2 3.3 5.3 3 2 1 5 5 5 0 AAA domain Reo_sigmaC PF04582.7 KKK17220.1 - 2.4 7.2 13.4 1.6 7.8 0.8 3.8 3 1 1 4 4 4 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KKK17220.1 - 8.6 6.1 83.5 0.65 9.7 2.2 6.5 4 1 1 6 6 6 0 TPR/MLP1/MLP2-like protein Fungal_trans PF04082.13 KKK17221.1 - 2.2e-12 46.3 0.2 3.8e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17221.1 - 0.0014 18.4 13.3 0.018 14.9 9.2 2.3 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.19 KKK17222.1 - 1.6e-11 44.0 0.0 2.3e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK17222.1 - 1.2e-07 31.7 0.0 1.3e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KKK17222.1 - 0.001 19.1 0.1 0.0072 16.4 0.0 2.1 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK17222.1 - 0.0069 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Metallophos PF00149.23 KKK17223.1 - 6.4e-37 126.8 0.2 2.7e-29 102.0 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase ALG3 PF05208.8 KKK17225.1 - 5.8e-134 446.9 15.4 6.9e-134 446.7 10.7 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 KKK17225.1 - 0.00024 20.1 11.4 0.00033 19.6 7.6 1.6 1 1 0 1 1 1 1 EpsG family eIF-1a PF01176.14 KKK17226.1 - 2.2e-16 59.0 0.0 3.5e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Zn_clus PF00172.13 KKK17227.1 - 8.2e-09 35.2 12.1 1.8e-08 34.1 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK17228.1 - 9e-09 34.5 3.3 1.3e-08 34.0 1.8 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17228.1 - 0.016 15.1 0.7 0.031 14.1 0.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Nsp1_C PF05064.8 KKK17228.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region Terpene_synth_C PF03936.11 KKK17229.1 - 1.4e-15 57.2 2.5 2.7e-15 56.3 1.8 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 KKK17231.1 - 1.1e-13 51.4 0.3 7.3e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KKK17231.1 - 0.0011 18.4 0.1 0.0026 17.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK17231.1 - 0.0026 17.4 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK17231.1 - 0.0078 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ATP-synt_F PF01990.12 KKK17231.1 - 0.066 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit MFS_1 PF07690.11 KKK17232.1 - 2.4e-36 125.1 57.7 1.6e-34 119.1 39.3 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily FMN_red PF03358.10 KKK17233.1 - 5.4e-30 103.9 0.0 6.9e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KKK17233.1 - 2.7e-07 30.2 0.0 3.7e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold DUF1604 PF07713.8 KKK17269.1 - 5.2e-41 138.3 2.1 3.3e-40 135.7 1.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KKK17269.1 - 7.7e-08 31.9 1.4 2.1e-07 30.5 1.0 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KKK17269.1 - 0.033 14.0 1.5 0.11 12.3 0.4 2.4 1 1 1 2 2 2 0 DExH-box splicing factor binding site ubiquitin PF00240.18 KKK17270.1 - 2.3e-06 26.9 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KKK17270.1 - 0.052 13.7 0.1 0.35 11.1 0.0 2.0 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain ABC2_membrane PF01061.19 KKK17271.1 - 2.8e-94 314.1 53.7 5.7e-48 162.8 14.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 KKK17271.1 - 7e-39 131.6 4.9 1.7e-32 111.1 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 KKK17271.1 - 4.7e-36 124.1 0.1 1e-17 64.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 KKK17271.1 - 4.3e-20 71.5 0.1 1.3e-19 70.0 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KKK17271.1 - 4.8e-10 39.0 45.3 7.3e-06 25.2 13.1 2.6 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 KKK17271.1 - 7.4e-09 35.2 0.0 0.00011 21.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK17271.1 - 5.6e-05 23.9 0.0 0.075 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KKK17271.1 - 6e-05 22.2 0.0 0.0041 16.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KKK17271.1 - 7.3e-05 22.6 0.8 0.14 11.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 KKK17271.1 - 0.00019 20.9 1.3 0.0023 17.4 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KKK17271.1 - 0.00034 20.6 0.1 0.028 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KKK17271.1 - 0.00046 20.5 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KKK17271.1 - 0.0033 17.5 0.6 0.59 10.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KKK17271.1 - 0.0043 16.5 3.2 0.043 13.3 0.2 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain NACHT PF05729.7 KKK17271.1 - 0.0086 15.7 2.2 2.7 7.6 0.1 2.8 3 0 0 3 3 3 2 NACHT domain RNA_helicase PF00910.17 KKK17271.1 - 0.014 15.5 0.2 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.14 KKK17271.1 - 0.016 14.4 0.1 1.1 8.4 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK17271.1 - 0.029 14.3 0.0 0.51 10.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KKK17271.1 - 0.034 13.8 0.2 2.6 7.8 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 KKK17271.1 - 0.053 13.1 0.8 0.59 9.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KKK17271.1 - 0.11 12.9 0.2 15 6.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KKK17271.1 - 0.13 12.4 0.1 12 6.1 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KKK17271.1 - 0.14 12.1 0.0 19 5.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 KKK17271.1 - 0.16 11.5 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KKK17271.1 - 0.36 11.1 0.3 3.8 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KKK17271.1 - 3 7.2 4.1 13 5.1 0.1 2.7 3 0 0 3 3 3 0 AAA-like domain PDR_assoc PF08370.6 KKK17271.1 - 6.7 6.2 9.1 0.35 10.4 0.1 3.3 4 0 0 4 4 3 0 Plant PDR ABC transporter associated Nop52 PF05997.7 KKK17272.1 - 8.3e-46 156.1 0.1 6.6e-37 127.0 0.1 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 RNA_pol_Rpc82 PF05645.8 KKK17272.1 - 0.012 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 DUF2956 PF11169.3 KKK17272.1 - 0.05 13.5 4.4 0.12 12.3 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) NARP1 PF12569.3 KKK17272.1 - 0.053 12.2 3.2 0.079 11.6 2.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3527 PF12043.3 KKK17272.1 - 0.058 12.9 1.3 0.3 10.5 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) FancD2 PF14631.1 KKK17272.1 - 0.099 9.7 0.2 0.13 9.3 0.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease HTH_IclR PF09339.5 KKK17272.1 - 0.1 12.2 2.0 0.18 11.3 0.1 2.4 3 1 0 3 3 3 0 IclR helix-turn-helix domain NOT2_3_5 PF04153.13 KKK17272.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family FLO_LFY PF01698.11 KKK17272.1 - 2.2 7.0 7.2 3.9 6.2 5.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Transp_cyt_pur PF02133.10 KKK17278.1 - 8.7e-91 304.6 43.2 1e-90 304.4 29.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.20 KKK17279.1 - 2e-14 53.3 0.0 1.1e-11 44.3 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17279.1 - 0.0047 16.0 0.1 0.11 11.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3437 PF11919.3 KKK17279.1 - 0.037 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) DUF4116 PF13475.1 KKK17279.1 - 0.11 12.0 0.1 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Pyrid_oxidase_2 PF13883.1 KKK17280.1 - 7.9e-37 126.6 0.0 1.1e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin PF08613.6 KKK17281.1 - 1e-14 55.2 0.1 3.9e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KKK17281.1 - 0.0028 17.2 0.1 0.0064 16.0 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Sugar_tr PF00083.19 KKK17282.1 - 2.1e-83 280.4 23.5 2.4e-83 280.2 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK17282.1 - 2.8e-21 75.6 47.5 9.2e-17 60.7 13.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.21 KKK17283.1 - 4.3e-10 39.3 7.1 1.3e-07 31.4 0.2 3.2 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK17283.1 - 1.6e-09 37.4 5.9 9e-06 25.6 0.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK17283.1 - 0.029 14.5 0.1 0.071 13.2 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KKK17283.1 - 0.033 14.4 0.7 0.033 14.4 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 KKK17283.1 - 0.095 12.9 2.5 0.14 12.3 0.0 2.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KKK17283.1 - 0.82 9.6 6.4 1.5 8.8 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger SecE PF00584.15 KKK17285.1 - 1.1e-10 40.9 0.0 1.2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Pyr_redox_2 PF07992.9 KKK17286.1 - 2.4e-41 141.8 12.6 4.8e-39 134.3 8.7 4.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KKK17286.1 - 2.8e-40 136.7 0.2 9.2e-40 135.1 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KKK17286.1 - 8.2e-23 80.6 10.6 4.3e-21 75.1 0.6 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK17286.1 - 1.3e-10 41.1 5.0 6.3e-06 26.1 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK17286.1 - 2.7e-10 40.6 0.9 6.2e-06 26.4 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK17286.1 - 3e-10 39.5 15.7 0.00011 21.2 0.1 4.2 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KKK17286.1 - 4.1e-10 39.3 9.8 6e-10 38.7 0.2 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KKK17286.1 - 3.3e-09 36.0 14.0 7.7e-08 31.5 3.0 3.2 2 2 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KKK17286.1 - 1.8e-07 30.3 2.0 1.8e-07 30.3 1.4 2.6 2 1 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 KKK17286.1 - 3.3e-06 26.2 1.0 0.057 12.3 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KKK17286.1 - 4.1e-06 25.5 14.4 0.0003 19.4 1.1 4.1 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.16 KKK17286.1 - 5e-06 26.1 3.1 0.0018 17.8 0.1 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KKK17286.1 - 2.2e-05 23.6 8.6 0.00017 20.7 0.7 2.5 1 1 0 2 2 2 2 Thi4 family THF_DHG_CYH_C PF02882.14 KKK17286.1 - 0.0024 16.9 1.1 0.25 10.3 0.0 3.9 3 2 1 4 4 4 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KKK17286.1 - 0.0079 15.8 5.7 0.011 15.3 0.9 2.7 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KKK17286.1 - 0.0082 15.2 12.1 0.2 10.7 0.5 3.3 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KKK17286.1 - 0.013 14.4 3.0 0.15 10.9 0.0 2.6 3 1 0 3 3 3 0 Lycopene cyclase protein DUF711 PF05167.7 KKK17286.1 - 0.027 13.1 0.2 0.057 12.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised ACR (DUF711) FMO-like PF00743.14 KKK17286.1 - 0.096 10.8 2.8 2.7 6.0 0.5 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.9 KKK17286.1 - 0.11 11.1 5.6 0.27 9.8 0.4 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.19 KKK17286.1 - 0.18 10.8 0.7 0.36 9.8 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 KKK17286.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.9 3 1 0 3 3 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KKK17286.1 - 0.87 8.9 5.3 1.6 8.0 0.3 2.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 KKK17286.1 - 0.97 9.4 4.3 1 9.3 0.0 2.6 2 1 1 3 3 2 0 NADH(P)-binding PGM_PMM_I PF02878.11 KKK17287.1 - 2e-34 118.0 0.0 3.6e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KKK17287.1 - 2e-22 79.4 0.0 7.7e-22 77.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KKK17287.1 - 1.4e-14 54.1 0.0 2.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KKK17287.1 - 3.4e-07 30.1 0.0 1.8e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CBF PF03914.12 KKK17290.1 - 5.7e-49 165.7 0.1 1.1e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 CBF/Mak21 family LemA PF04011.7 KKK17290.1 - 0.043 12.9 0.2 0.095 11.7 0.2 1.5 1 0 0 1 1 1 0 LemA family Mt_ATP-synt_B PF05405.9 KKK17291.1 - 5.3e-52 175.5 8.2 8.1e-52 174.9 5.7 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sel1 PF08238.7 KKK17291.1 - 4.7e-16 58.8 1.9 9.5e-07 29.2 0.0 3.6 3 0 0 3 3 3 3 Sel1 repeat PCI PF01399.22 KKK17292.1 - 2.2e-11 43.9 0.0 4.5e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 KKK17292.1 - 6.4e-08 32.1 0.8 1e-07 31.4 0.6 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 KKK17292.1 - 0.004 17.4 1.8 0.01 16.1 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK17292.1 - 0.065 13.0 0.3 7.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Herpes_UL14 PF03580.9 KKK17292.1 - 0.31 10.8 4.9 6.6 6.5 0.8 2.4 1 1 1 2 2 2 0 Herpesvirus UL14-like protein TPR_14 PF13428.1 KKK17292.1 - 3.6 8.4 10.4 17 6.3 0.8 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat FAD_binding_2 PF00890.19 KKK17293.1 - 1e-84 284.8 1.3 1.2e-84 284.5 0.9 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KKK17293.1 - 6.3e-21 73.9 1.2 6.5e-19 67.5 0.0 3.3 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KKK17293.1 - 3.5e-12 45.8 2.6 1.2e-11 44.1 1.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KKK17293.1 - 9.8e-10 38.0 0.7 3.7e-09 36.1 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK17293.1 - 2.5e-08 33.8 2.0 1.6e-07 31.2 0.2 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK17293.1 - 5.7e-08 32.8 0.0 8.1e-06 25.8 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK17293.1 - 5.8e-07 28.3 4.4 0.0016 17.0 0.2 3.2 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 KKK17293.1 - 9.9e-05 21.5 0.9 0.013 14.5 0.3 2.6 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 KKK17293.1 - 0.00047 19.3 0.3 0.1 11.6 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KKK17293.1 - 0.00055 19.0 0.4 0.0013 17.8 0.3 1.5 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KKK17293.1 - 0.001 18.0 2.6 0.24 10.1 0.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KKK17293.1 - 0.0014 18.4 0.7 0.0073 16.0 0.5 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KKK17293.1 - 0.0087 16.1 1.2 0.042 13.9 0.8 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK17293.1 - 0.048 14.0 1.6 4.1 7.8 0.2 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KKK17293.1 - 0.26 9.5 0.1 0.42 8.8 0.1 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor bZIP_Maf PF03131.12 KKK17295.1 - 1.5e-07 31.6 10.5 1.5e-07 31.6 7.3 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KKK17295.1 - 2e-06 27.5 19.4 5.1e-06 26.1 8.4 2.5 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KKK17295.1 - 4.7e-06 26.4 20.3 1.9e-05 24.5 9.7 2.5 2 0 0 2 2 2 2 bZIP transcription factor Herpes_U5 PF05999.6 KKK17295.1 - 0.013 14.0 1.7 0.019 13.5 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus U5-like family Endotoxin_N PF03945.9 KKK17295.1 - 1 8.7 7.3 0.17 11.2 2.4 1.7 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain zf-CCCH PF00642.19 KKK17296.1 - 6.5e-13 48.0 29.6 7.5e-06 25.4 1.0 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KKK17296.1 - 1.6 8.3 5.2 0.7 9.4 0.0 2.8 3 0 0 3 3 3 0 Putative zinc-finger domain WD40 PF00400.27 KKK17298.1 - 1.7e-13 49.8 3.6 0.084 12.8 0.2 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat PAH PF02671.16 KKK17299.1 - 1.6e-46 155.6 2.9 6.1e-17 60.9 0.5 4.4 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KKK17299.1 - 4.3e-41 138.7 0.0 1.2e-40 137.2 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Filament PF00038.16 KKK17300.1 - 3e-05 23.6 34.7 0.0022 17.5 24.1 2.2 1 1 0 1 1 1 1 Intermediate filament protein DUF812 PF05667.6 KKK17300.1 - 5.3e-05 21.9 20.6 6.9e-05 21.5 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 KKK17300.1 - 8.6e-05 21.8 1.8 0.014 14.6 0.1 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein APG6 PF04111.7 KKK17300.1 - 0.0012 17.9 37.1 0.0059 15.6 12.1 2.1 1 1 1 2 2 2 2 Autophagy protein Apg6 Cep57_MT_bd PF06657.8 KKK17300.1 - 0.017 15.0 3.1 0.017 15.0 2.1 4.4 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Phyto_Pns9_10 PF05878.6 KKK17300.1 - 0.038 13.0 9.7 0.056 12.4 6.7 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 SlyX PF04102.7 KKK17300.1 - 0.058 13.7 16.8 0.8 10.1 0.3 5.0 2 2 3 5 5 5 0 SlyX TMPIT PF07851.8 KKK17300.1 - 0.14 11.2 23.3 0.063 12.3 3.9 2.5 1 1 0 2 2 2 0 TMPIT-like protein Bacillus_HBL PF05791.6 KKK17300.1 - 0.21 10.9 14.1 0.12 11.7 1.7 2.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 KKK17300.1 - 0.4 10.2 33.3 1.2 8.6 9.6 2.7 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 KKK17300.1 - 0.45 10.4 34.8 0.25 11.2 10.0 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 KKK17300.1 - 0.96 8.0 30.6 0.38 9.3 9.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.6 KKK17300.1 - 1.1 9.0 32.1 2.7 7.7 5.6 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMCO5 PF14992.1 KKK17300.1 - 1.2 8.1 25.2 0.47 9.5 8.0 2.2 1 1 1 2 2 2 0 TMCO5 family Atg14 PF10186.4 KKK17300.1 - 1.6 7.5 30.8 1.7 7.5 7.7 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 KKK17300.1 - 1.9 8.6 17.2 0.85 9.7 1.3 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.3 KKK17300.1 - 2.4 5.3 33.6 0.9 6.7 9.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 KKK17300.1 - 2.4 7.9 32.6 0.6 9.8 10.6 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Tup_N PF08581.5 KKK17300.1 - 3.3 7.9 29.3 0.47 10.6 4.9 3.4 3 0 0 3 3 3 0 Tup N-terminal L31 PF09784.4 KKK17300.1 - 3.7 7.6 14.4 0.13 12.3 1.9 2.5 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 TSC22 PF01166.13 KKK17300.1 - 6.8 6.7 16.1 0.51 10.3 0.1 4.2 2 2 2 4 4 4 0 TSC-22/dip/bun family DUF2265 PF10023.4 KKK17300.1 - 7.4 5.6 21.6 8.6 5.3 4.7 3.2 1 1 2 3 3 3 0 Predicted aminopeptidase (DUF2265) FH2 PF02181.18 KKK17300.1 - 7.4 5.3 22.3 2.7 6.8 6.6 2.5 1 1 1 2 2 2 0 Formin Homology 2 Domain CorA PF01544.13 KKK17300.1 - 9 5.2 19.1 2.8 6.8 0.3 2.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF3106 PF11304.3 KKK17300.1 - 9.1 6.7 19.5 1.2 9.5 5.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3106) GPI-anchored PF10342.4 KKK17301.1 - 1.1e-15 57.8 1.8 2.8e-15 56.5 1.2 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_5 PF13205.1 KKK17301.1 - 0.0095 16.5 1.5 0.016 15.7 0.1 2.0 2 0 0 2 2 2 1 Bacterial Ig-like domain TFIIF_beta PF02270.10 KKK17302.1 - 2.3e-86 290.0 4.2 2.7e-86 289.7 2.9 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF859 PF05895.7 KKK17302.1 - 0.15 10.2 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) Fungal_trans PF04082.13 KKK17304.1 - 1.9e-20 72.8 0.0 2.8e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17304.1 - 2.3e-05 24.2 17.5 5e-05 23.1 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 KKK17304.1 - 0.062 13.5 0.8 0.13 12.4 0.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Clusterin PF01093.12 KKK17304.1 - 2.6 6.7 3.1 3.8 6.1 2.2 1.1 1 0 0 1 1 1 0 Clusterin DHquinase_I PF01487.10 KKK17305.1 - 4.4e-55 186.7 0.0 6.4e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase DENN PF02141.16 KKK17306.1 - 4.3e-56 189.5 0.1 7.3e-56 188.8 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KKK17306.1 - 9.7e-19 67.2 0.7 9.7e-19 67.2 0.5 1.9 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 KKK17306.1 - 9.2e-18 63.9 0.0 2e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 uDENN domain C1_3 PF07649.7 KKK17306.1 - 0.0018 18.2 3.8 0.0038 17.2 2.6 1.6 1 0 0 1 1 1 1 C1-like domain C1_1 PF00130.17 KKK17306.1 - 0.0035 17.0 10.6 0.0068 16.1 7.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.11 KKK17306.1 - 0.0066 16.5 5.8 0.016 15.3 4.0 1.6 1 0 0 1 1 1 1 C1 domain SPA PF08616.5 KKK17306.1 - 0.076 12.7 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.24 KKK17306.1 - 0.14 11.8 9.4 0.035 13.7 3.9 2.0 1 1 1 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 KKK17306.1 - 4.4 7.1 13.4 0.63 9.8 5.8 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Mt_ATP-synt_D PF05873.7 KKK17307.1 - 7.8e-20 71.1 1.7 1e-19 70.7 1.2 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Oxysterol_BP PF01237.13 KKK17307.1 - 0.003 16.0 1.7 0.0035 15.8 1.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein EzrA PF06160.7 KKK17307.1 - 0.033 12.3 4.4 0.04 12.1 2.4 1.5 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA BLOC1_2 PF10046.4 KKK17307.1 - 0.28 11.3 2.3 0.56 10.3 1.6 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.4 KKK17307.1 - 0.44 10.4 2.8 0.88 9.5 1.9 1.6 1 1 0 1 1 1 0 Haemolysin XhlA DUF148 PF02520.12 KKK17307.1 - 0.82 9.4 6.6 0.2 11.4 2.3 1.6 2 1 0 2 2 2 0 Domain of unknown function DUF148 Spectrin PF00435.16 KKK17307.1 - 1.3 9.2 5.4 3 8.1 0.9 2.1 1 1 1 2 2 2 0 Spectrin repeat Tropomyosin_1 PF12718.2 KKK17307.1 - 6.7 6.5 8.8 15 5.4 2.3 2.4 1 1 0 2 2 2 0 Tropomyosin like NAC PF01849.13 KKK17308.1 - 4.7e-25 86.8 0.0 3.3e-23 80.9 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KKK17308.1 - 0.00078 19.2 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CDC45 PF02724.9 KKK17308.1 - 0.021 12.8 2.9 0.03 12.3 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 KKK17308.1 - 0.21 10.5 0.5 0.22 10.5 0.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter UreE_C PF05194.7 KKK17308.1 - 2 8.5 8.2 4.7 7.3 5.7 1.8 1 1 0 1 1 1 0 UreE urease accessory protein, C-terminal domain TRAP_alpha PF03896.11 KKK17308.1 - 3.7 6.4 5.9 6.4 5.6 4.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SpoIIIAH PF12685.2 KKK17308.1 - 7.1 6.0 10.1 0.82 9.1 3.7 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein Ribosomal_L14e PF01929.12 KKK17309.1 - 8.4e-25 86.9 0.6 1.5e-24 86.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KKK17309.1 - 1.2e-07 31.0 1.0 2.5e-07 30.1 0.7 1.5 1 0 0 1 1 1 1 KOW motif YIF1 PF03878.10 KKK17310.1 - 1.2e-76 257.0 3.0 1.5e-76 256.7 2.1 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KKK17310.1 - 1e-05 25.0 6.2 1e-05 25.0 4.3 1.8 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.8 KKK17311.1 - 1.7e-84 283.4 0.0 2.4e-84 283.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KKK17311.1 - 3.1e-50 170.3 0.0 5.2e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KKK17311.1 - 8.8e-08 32.1 0.1 2.5e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KKK17311.1 - 1.4e-05 24.0 0.0 2.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KKK17311.1 - 1.4e-05 24.5 0.1 2.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 KKK17311.1 - 6.5e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KKK17311.1 - 0.0027 17.1 0.1 0.021 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 KKK17311.1 - 0.0043 16.7 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Luteo_Vpg PF01659.11 KKK17311.1 - 0.011 15.3 0.1 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein Fer4_NifH PF00142.13 KKK17311.1 - 0.029 13.5 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.1 KKK17311.1 - 0.07 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 KKK17311.1 - 0.11 12.4 1.4 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KKK17311.1 - 0.13 12.3 0.0 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KKK17311.1 - 0.14 12.0 0.3 0.9 9.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.11 KKK17312.1 - 1.7e-40 138.8 44.4 1.6e-34 119.1 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK17312.1 - 3.5e-11 42.3 15.0 7.4e-11 41.2 0.4 2.6 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 KKK17312.1 - 5e-10 38.3 0.0 1.3e-05 23.7 0.6 3.6 1 1 3 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.2 KKK17312.1 - 0.002 17.8 3.1 0.013 15.2 0.0 3.3 3 0 0 3 3 3 1 MFS_1 like family TRI12 PF06609.8 KKK17312.1 - 0.003 15.8 1.0 0.0048 15.1 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 KKK17312.1 - 0.043 12.3 0.8 0.06 11.8 0.0 1.6 2 0 0 2 2 2 0 Reduced folate carrier TPR_12 PF13424.1 KKK17313.1 - 5.6e-25 87.0 13.1 1e-10 41.4 2.2 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KKK17313.1 - 2.1e-11 43.3 7.4 0.0011 18.7 0.4 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK17313.1 - 3.4e-07 30.7 10.6 0.0062 17.1 0.0 4.3 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK17313.1 - 2.1e-06 27.0 8.1 0.056 13.2 0.1 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK17313.1 - 0.0018 18.0 15.1 2.4 8.2 0.7 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 KKK17313.1 - 0.003 17.7 0.1 0.003 17.7 0.0 3.6 4 0 0 4 4 2 1 C2H2-type zinc finger TPR_8 PF13181.1 KKK17313.1 - 0.015 15.0 4.8 0.17 11.7 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 KKK17313.1 - 0.018 15.3 0.7 0.018 15.3 0.5 4.4 4 0 0 4 4 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK17313.1 - 0.021 14.9 0.1 0.021 14.9 0.1 3.2 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding TPR_11 PF13414.1 KKK17313.1 - 0.025 14.2 9.4 3.2 7.4 0.2 4.6 2 2 1 5 5 5 0 TPR repeat zf-met PF12874.2 KKK17313.1 - 0.033 14.3 2.9 0.094 12.9 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MIP-T3 PF10243.4 KKK17313.1 - 0.21 10.0 13.6 0.34 9.3 9.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TPR_14 PF13428.1 KKK17313.1 - 0.35 11.6 14.2 9.8 7.1 0.0 6.1 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 KKK17313.1 - 0.57 10.5 3.1 24 5.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KKK17313.1 - 0.6 9.8 3.4 20 4.9 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_3 PF14369.1 KKK17313.1 - 2.3 8.2 8.3 2.9 7.9 1.5 3.5 3 0 0 3 3 3 0 zinc-finger Menin PF05053.8 KKK17313.1 - 2.4 6.2 7.2 4 5.4 5.0 1.2 1 0 0 1 1 1 0 Menin TMF_TATA_bd PF12325.3 KKK17316.1 - 0.022 14.4 2.0 0.035 13.8 1.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YpzG PF14139.1 KKK17316.1 - 0.13 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 YpzG-like protein DUF1682 PF07946.9 KKK17316.1 - 9.8 4.9 8.9 15 4.3 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PGM_PMM_I PF02878.11 KKK17318.1 - 4.4e-32 110.4 0.1 6.8e-32 109.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KKK17318.1 - 3.8e-25 88.1 0.0 7.7e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KKK17318.1 - 1.4e-14 54.2 0.0 3.1e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KKK17318.1 - 1.6e-09 37.5 0.0 4.1e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ATP-grasp_2 PF08442.5 KKK17319.1 - 5.5e-55 185.8 0.0 7.7e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KKK17319.1 - 1.5e-10 40.8 0.2 2.5e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KKK17319.1 - 2.4e-10 40.0 0.0 2.1e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KKK17319.1 - 0.0032 17.2 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KKK17319.1 - 0.0054 16.3 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.17 KKK17319.1 - 0.016 14.6 0.0 0.042 13.1 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.12 KKK17319.1 - 0.037 13.3 0.0 0.082 12.1 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Syndecan PF01034.15 KKK17320.1 - 0.26 10.9 0.3 0.53 9.9 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Gly-zipper_OmpA PF13436.1 KKK17320.1 - 4.2 7.0 11.0 1.5 8.5 4.9 2.3 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain TauD PF02668.11 KKK17321.1 - 6.1e-05 22.8 0.1 0.00011 21.9 0.0 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KKK17321.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 CsiD AMP-binding PF00501.23 KKK17322.1 - 1.4e-71 241.1 0.0 2.3e-71 240.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KKK17322.1 - 1.5e-20 73.2 0.1 5.8e-14 51.6 0.0 3.4 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 KKK17322.1 - 3.3e-09 36.8 0.0 8.9e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK17322.1 - 2.1e-06 28.5 0.0 7.4e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zeta_toxin PF06414.7 KKK17322.1 - 0.19 10.8 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Acetyltransf_10 PF13673.1 KKK17323.1 - 0.054 13.6 0.1 0.12 12.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain 2OG-FeII_Oxy PF03171.15 KKK17324.1 - 1.4e-12 47.7 0.0 2.4e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KKK17324.1 - 1.8e-06 28.4 0.0 3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF2746 PF10874.3 KKK17324.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Aldo_ket_red PF00248.16 KKK17326.1 - 8.5e-35 119.9 0.0 1.8e-24 86.0 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family AMP-binding PF00501.23 KKK17327.1 - 3.4e-75 253.0 0.0 6.3e-75 252.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KKK17327.1 - 7.2e-40 136.4 0.0 1.6e-39 135.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.15 KKK17327.1 - 1.2e-35 122.8 1.1 1.9e-35 122.1 0.0 1.9 3 0 0 3 3 3 1 Condensation domain Epimerase PF01370.16 KKK17327.1 - 4.5e-11 42.6 0.0 9.8e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KKK17327.1 - 5.7e-06 26.5 0.1 3.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK17327.1 - 2.1e-05 25.3 0.9 2.1e-05 25.3 0.6 3.7 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KKK17327.1 - 0.00017 20.3 0.0 0.00034 19.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KKK17327.1 - 0.00053 20.2 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KKK17327.1 - 0.029 13.2 0.0 0.18 10.6 0.0 2.3 1 1 0 1 1 1 0 RmlD substrate binding domain MFS_1 PF07690.11 KKK17328.1 - 8e-31 107.0 29.2 1.1e-30 106.5 20.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK17328.1 - 3.1e-07 29.3 8.3 3.1e-07 29.3 5.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KKK17328.1 - 1.2e-05 23.8 10.2 1.2e-05 23.8 7.1 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein LacY_symp PF01306.14 KKK17328.1 - 0.017 13.7 0.9 0.017 13.7 0.6 1.8 2 0 0 2 2 2 0 LacY proton/sugar symporter OATP PF03137.15 KKK17328.1 - 0.042 11.9 4.7 0.043 11.8 2.0 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1705 PF08019.7 KKK17328.1 - 0.061 12.8 1.7 0.35 10.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) RNase_T PF00929.19 KKK17329.1 - 1.5e-17 64.3 0.0 1.7e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 Exonuclease GFO_IDH_MocA PF01408.17 KKK17330.1 - 6.1e-11 42.8 0.0 2.5e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ilar_coat PF01787.11 KKK17330.1 - 0.091 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Ilarvirus coat protein peroxidase PF00141.18 KKK17331.1 - 1.2e-43 149.2 0.0 1.8e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ArfGap PF01412.13 KKK17332.1 - 2.1e-37 127.4 0.3 3.3e-37 126.8 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 KKK17332.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Sec7 PF01369.15 KKK17342.1 - 2.8e-58 196.7 0.0 4.7e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KKK17342.1 - 1.7e-17 63.3 0.2 4.3e-16 58.8 0.0 2.8 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3337 PF11816.3 KKK17343.1 - 1.3e-101 340.3 0.4 5e-96 321.9 3.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) ATP_bind_3 PF01171.15 KKK17343.1 - 1.2e-41 142.2 0.0 1.8e-40 138.3 0.0 2.3 1 1 0 1 1 1 1 PP-loop family WD40 PF00400.27 KKK17343.1 - 1e-19 69.6 17.9 1.9e-07 30.6 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Asn_synthase PF00733.16 KKK17343.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase RhoGEF PF00621.15 KKK17344.1 - 1.6e-23 83.5 0.0 3.5e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 KKK17344.1 - 9.3e-08 31.7 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) RhoGAP PF00620.22 KKK17344.1 - 0.047 13.2 0.1 5 6.7 0.0 2.8 2 0 0 2 2 2 0 RhoGAP domain Pkinase PF00069.20 KKK17345.1 - 3.8e-56 190.1 0.0 2.6e-55 187.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17345.1 - 2.2e-19 69.5 0.0 3.5e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK17345.1 - 0.019 14.7 0.2 0.048 13.3 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KKK17345.1 - 0.16 10.9 0.0 0.36 9.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KKK17345.1 - 0.34 9.9 1.0 0.53 9.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.22 KKK17346.1 - 4.4e-42 141.6 4.0 2.8e-15 55.8 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3943 PF13084.1 KKK17346.1 - 0.06 12.9 0.1 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) Svf1 PF08622.5 KKK17347.1 - 7.4e-07 28.4 0.5 1.5e-06 27.4 0.5 1.4 2 0 0 2 2 2 1 Svf1-like Ribosomal_L11 PF00298.14 KKK17348.1 - 3.7e-18 65.4 1.3 5.9e-18 64.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 KKK17348.1 - 3.4e-14 52.0 0.1 1.8e-13 49.7 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain RNase_PH PF01138.16 KKK17349.1 - 3e-31 108.4 1.2 6.3e-31 107.4 0.4 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Pro_isomerase PF00160.16 KKK17350.1 - 7.7e-13 48.9 0.2 8.8e-13 48.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ssu72 PF04722.8 KKK17351.1 - 4.7e-84 280.5 0.0 5.6e-84 280.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.6 KKK17351.1 - 0.11 11.9 3.9 0.16 11.3 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KKK17351.1 - 3.3 6.9 9.3 5.8 6.1 6.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SNF2_N PF00176.18 KKK17352.1 - 1e-53 182.0 0.2 1.8e-53 181.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KKK17352.1 - 1.4e-25 88.9 0.6 3.2e-25 87.8 0.4 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KKK17352.1 - 8.7e-17 60.7 0.3 1.8e-14 53.3 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK17352.1 - 0.00047 19.7 0.0 0.0018 17.8 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KKK17352.1 - 0.022 14.6 2.8 0.043 13.6 0.1 3.0 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KKK17352.1 - 0.025 13.3 0.0 0.06 12.1 0.0 1.6 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.1 KKK17352.1 - 0.073 11.8 0.4 8.5 5.0 0.0 3.3 4 0 0 4 4 4 0 P-loop containing NTP hydrolase pore-1 Lipocalin_3 PF12702.2 KKK17352.1 - 0.18 11.8 1.7 0.59 10.1 0.1 2.6 3 0 0 3 3 3 0 Lipocalin-like DUF3605 PF12239.3 KKK17353.1 - 2e-62 209.7 0.2 2.4e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.15 KKK17354.1 - 1.5e-22 80.3 0.1 2.7e-22 79.5 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family Oxysterol_BP PF01237.13 KKK17355.1 - 7e-91 304.3 0.0 9.3e-91 303.9 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein DUF1230 PF06799.6 KKK17355.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1230) GTP_EFTU PF00009.22 KKK17359.1 - 1.1e-59 201.0 0.1 1.9e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KKK17359.1 - 8.1e-37 125.4 0.0 1.7e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KKK17359.1 - 1.4e-20 72.8 0.0 4.5e-20 71.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KKK17359.1 - 5.7e-13 48.7 0.0 2.3e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KKK17359.1 - 4.4e-11 42.4 0.0 1.4e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KKK17359.1 - 1.4e-05 25.0 0.0 3.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.11 KKK17361.1 - 3.5e-98 328.2 1.1 4.7e-98 327.8 0.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha RRM_6 PF14259.1 KKK17362.1 - 9.7e-11 41.5 0.0 3.1e-09 36.6 0.0 2.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KKK17362.1 - 3.9e-10 39.6 0.1 8.4e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 KKK17362.1 - 3.7e-09 36.2 0.0 7.5e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK17362.1 - 2.5e-07 30.1 0.1 3.8e-05 23.2 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK17362.1 - 5.6e-06 26.0 0.0 0.00065 19.4 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KKK17362.1 - 0.00096 18.7 1.0 0.0018 17.9 0.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.6 KKK17362.1 - 0.03 14.1 0.1 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Borrelia_P83 PF05262.6 KKK17362.1 - 0.14 10.3 8.3 0.21 9.8 5.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RRM_3 PF08777.6 KKK17362.1 - 0.16 11.7 0.0 0.16 11.7 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif VIT1 PF01988.14 KKK17362.1 - 0.46 9.9 5.6 0.62 9.5 3.3 1.5 2 0 0 2 2 2 0 VIT family Ycf1 PF05758.7 KKK17362.1 - 3.3 5.2 5.2 4.5 4.8 3.6 1.1 1 0 0 1 1 1 0 Ycf1 Ubie_methyltran PF01209.13 KKK17363.1 - 3.9e-80 268.3 0.0 5.3e-80 267.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KKK17363.1 - 7.3e-15 55.2 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK17363.1 - 2.3e-14 53.2 0.0 3.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK17363.1 - 2.6e-10 40.2 0.0 3.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK17363.1 - 2e-09 37.8 0.0 3.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK17363.1 - 2.6e-08 34.1 0.0 5.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK17363.1 - 1.4e-07 32.0 0.0 2.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK17363.1 - 1.7e-05 24.8 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KKK17363.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Glyco_hydro_2 PF00703.16 KKK17364.1 - 3.4e-05 24.2 0.0 9.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KKK17364.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF4299 PF14132.1 KKK17364.1 - 0.076 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) E1_dh PF00676.15 KKK17365.1 - 3.4e-86 288.6 0.0 4.1e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KKK17365.1 - 0.00012 21.6 0.0 0.0017 17.9 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 KKK17365.1 - 0.0067 15.0 0.0 0.014 14.0 0.0 1.4 1 0 0 1 1 1 1 XFP N-terminal domain DXP_synthase_N PF13292.1 KKK17365.1 - 0.086 11.7 0.0 0.81 8.5 0.0 2.2 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Elongin_A PF06881.6 KKK17365.1 - 0.11 12.9 3.7 0.55 10.6 3.2 1.6 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Thi4 PF01946.12 KKK17381.1 - 2.9e-102 340.6 0.0 3.6e-102 340.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KKK17381.1 - 1.4e-08 34.0 0.3 2.8e-08 33.0 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK17381.1 - 8.1e-06 25.7 0.2 5.3e-05 23.1 0.1 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK17381.1 - 1.9e-05 23.7 0.3 3.7e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KKK17381.1 - 0.00011 22.0 0.2 0.00036 20.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KKK17381.1 - 0.001 19.2 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK17381.1 - 0.002 18.0 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK17381.1 - 0.0067 15.3 0.9 0.025 13.4 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KKK17381.1 - 0.029 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KKK17381.1 - 0.038 13.0 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KKK17381.1 - 0.1 11.2 0.2 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 KKK17381.1 - 0.19 10.1 0.5 0.29 9.5 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein WD40 PF00400.27 KKK17382.1 - 3.4e-59 194.7 20.2 3.3e-13 48.9 0.2 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KKK17382.1 - 8.1e-09 35.4 0.0 0.0026 17.4 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KKK17382.1 - 1.8e-07 29.6 1.7 0.34 8.9 0.1 4.5 2 2 3 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KKK17382.1 - 0.0017 17.8 0.7 0.62 9.4 0.1 3.1 2 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 KKK17382.1 - 0.0054 16.3 0.1 14 5.4 0.0 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 KKK17382.1 - 0.18 10.0 0.0 0.37 8.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) SWI-SNF_Ssr4 PF08549.5 KKK17383.1 - 0 1124.6 11.4 0 1124.4 7.9 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) MFS_1 PF07690.11 KKK17384.1 - 3.1e-34 118.2 25.8 3.1e-34 118.2 17.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Exo_endo_phos PF03372.18 KKK17385.1 - 4.8e-18 66.0 0.5 9.8e-18 64.9 0.4 1.4 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.4 KKK17385.1 - 0.13 11.3 0.2 0.26 10.3 0.0 1.5 2 0 0 2 2 2 0 Luciferase catalytic domain 2TM PF13239.1 KKK17385.1 - 0.85 9.7 3.8 0.52 10.4 0.3 2.1 2 0 0 2 2 2 0 2TM domain Pkinase PF00069.20 KKK17386.1 - 4.2e-17 62.1 0.0 2.2e-07 30.2 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17386.1 - 0.031 13.3 3.0 0.72 8.8 0.0 2.5 2 1 1 3 3 3 0 Protein tyrosine kinase Arf PF00025.16 KKK17387.1 - 3.6e-43 146.8 0.0 4.3e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KKK17387.1 - 1.8e-18 66.4 0.0 2.1e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK17387.1 - 3.3e-09 37.2 0.0 5.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK17387.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KKK17387.1 - 1.7e-06 27.3 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KKK17387.1 - 3.1e-06 26.5 0.0 3.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KKK17387.1 - 8.4e-05 22.0 0.0 0.00083 18.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 KKK17387.1 - 9.3e-05 21.2 0.2 0.00025 19.8 0.0 1.7 2 1 1 3 3 3 1 G-protein alpha subunit Dynamin_N PF00350.18 KKK17387.1 - 0.00099 18.9 0.1 0.016 14.9 0.1 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 KKK17387.1 - 0.014 14.7 0.2 0.11 11.7 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B RCR PF12273.3 KKK17388.1 - 3.1e-28 98.9 10.6 5.1e-28 98.2 7.3 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF2668 PF10873.3 KKK17388.1 - 0.0029 17.7 0.6 0.0029 17.7 0.4 1.7 1 1 0 2 2 2 1 Protein of unknown function (DUF2668) LysE PF01810.13 KKK17388.1 - 0.0046 16.2 0.2 0.0058 15.9 0.1 1.1 1 0 0 1 1 1 1 LysE type translocator Shisa PF13908.1 KKK17388.1 - 0.0058 16.8 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Rhabdo_glycop PF00974.13 KKK17388.1 - 0.019 13.2 0.1 0.024 12.8 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Acyl_transf_3 PF01757.17 KKK17388.1 - 0.041 12.7 1.1 0.052 12.3 0.8 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF1183 PF06682.7 KKK17388.1 - 0.044 13.3 0.1 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Cytochrom_B_N PF00033.14 KKK17388.1 - 0.059 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Tetraspannin PF00335.15 KKK17388.1 - 0.088 12.0 0.2 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF1180 PF06679.7 KKK17388.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Hum_adeno_E3A PF05393.6 KKK17388.1 - 0.15 11.7 0.3 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF2839 PF10999.3 KKK17388.1 - 0.59 10.2 4.2 7.2 6.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Pil1 PF13805.1 KKK17389.1 - 1.6e-90 302.9 3.5 2.8e-90 302.1 2.4 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KKK17389.1 - 0.061 12.6 1.3 0.11 11.8 0.9 1.5 1 0 0 1 1 1 0 FAM92 protein DUF1018 PF06252.7 KKK17389.1 - 0.11 13.0 2.0 1.5 9.3 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) Proteasome PF00227.21 KKK17390.1 - 2e-44 151.1 0.3 1.7e-34 118.7 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit RNA_pol_Rpb2_6 PF00562.23 KKK17391.1 - 5.2e-118 394.1 0.0 7e-118 393.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KKK17391.1 - 1.3e-29 102.6 0.0 2.4e-29 101.7 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KKK17391.1 - 2.6e-26 92.2 0.0 4.3e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 KKK17391.1 - 6e-25 86.9 0.0 1.6e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 KKK17391.1 - 7.8e-24 83.2 0.0 2.1e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 KKK17391.1 - 9.7e-15 54.6 0.0 3.8e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KKK17391.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Ppx-GppA PF02541.11 KKK17392.1 - 3.8e-43 147.7 0.0 5.5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 KKK17392.1 - 0.0041 15.6 0.0 0.0077 14.7 0.0 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Selenoprotein_S PF06936.6 KKK17393.1 - 0.89 9.0 7.9 0.053 13.0 0.5 2.4 2 0 0 2 2 2 0 Selenoprotein S (SelS) Pkinase PF00069.20 KKK17394.1 - 2.2e-70 236.8 0.0 3.5e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17394.1 - 7.4e-30 103.8 0.0 1.6e-28 99.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK17394.1 - 2.3e-06 26.8 0.1 0.15 11.0 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 KKK17394.1 - 0.026 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK17394.1 - 0.13 11.9 0.0 6.8 6.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family His_Phos_2 PF00328.17 KKK17396.1 - 4.5e-14 52.5 0.0 1.4e-13 50.9 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ILVD_EDD PF00920.16 KKK17397.1 - 7.1e-167 555.9 0.5 8e-167 555.7 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family eIF-5a PF01287.15 KKK17399.1 - 8.9e-27 92.8 1.3 1.3e-26 92.3 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KKK17399.1 - 1.7e-05 24.3 1.5 4.1e-05 23.1 1.0 1.7 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KKK17399.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Nitro_FeMo-Co PF02579.12 KKK17399.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Vps52 PF04129.7 KKK17400.1 - 4.8e-108 361.9 0.0 6.9e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family DAO PF01266.19 KKK17400.1 - 2e-54 184.8 0.3 3.4e-54 184.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK17400.1 - 9.8e-06 25.5 0.3 0.00018 21.4 0.1 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK17400.1 - 7e-05 22.9 0.0 0.00021 21.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK17400.1 - 0.005 15.7 1.6 0.022 13.6 1.1 1.9 1 1 0 1 1 1 1 FAD binding domain Sec8_exocyst PF04048.9 KKK17400.1 - 0.011 15.4 0.1 0.027 14.0 0.1 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Pyr_redox_2 PF07992.9 KKK17400.1 - 0.012 15.5 0.1 0.14 12.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK17400.1 - 0.022 13.8 0.0 0.073 12.1 0.0 1.8 1 0 0 1 1 1 0 Thi4 family zf-C2H2 PF00096.21 KKK17401.1 - 2.1e-07 30.8 15.4 0.0011 19.1 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK17401.1 - 1.4e-06 28.2 8.8 1.4e-06 28.2 6.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK17401.1 - 1.1e-05 25.4 12.1 0.016 15.4 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KKK17401.1 - 8.1e-05 22.6 8.9 0.069 13.3 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Fungal_trans PF04082.13 KKK17401.1 - 0.00064 18.6 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.3 KKK17401.1 - 0.0012 18.9 11.2 0.032 14.3 2.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KKK17401.1 - 0.01 15.6 7.9 0.024 14.5 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KKK17401.1 - 6 6.6 9.7 17 5.1 2.5 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type CoA_trans PF01144.18 KKK17402.1 - 4.7e-97 323.3 1.5 3.6e-58 196.2 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF531 PF04407.7 KKK17402.1 - 0.083 12.7 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF531) PPTA PF01239.17 KKK17403.1 - 0.035 13.4 3.4 0.52 9.7 0.3 2.7 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.9 KKK17404.1 - 1.4e-61 206.8 3.0 1.8e-61 206.5 2.1 1.1 1 0 0 1 1 1 1 CHD5-like protein mRNA_cap_C PF03919.10 KKK17404.1 - 0.1 12.8 0.7 0.17 12.2 0.5 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain DUF2929 PF11151.3 KKK17404.1 - 1.5 8.9 7.0 1.8 8.7 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) Pribosyltran PF00156.22 KKK17405.1 - 5.5e-15 55.1 0.3 9e-15 54.5 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF3186 PF11382.3 KKK17405.1 - 0.02 14.0 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) MTHFR PF02219.12 KKK17406.1 - 6e-114 379.9 0.0 8.1e-114 379.5 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF2418 PF10332.4 KKK17408.1 - 4.5e-35 119.9 0.1 4.5e-35 119.9 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 KKK17409.1 - 1.1e-25 89.8 0.0 1.4e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 KKK17409.1 - 0.046 13.0 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Myc_N PF01056.13 KKK17411.1 - 0.0077 15.4 0.2 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Nro1 PF12753.2 KKK17411.1 - 0.09 11.7 2.0 0.084 11.8 0.3 1.7 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 GMC_oxred_N PF00732.14 KKK17412.1 - 1.8e-34 119.2 0.0 2.1e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KKK17412.1 - 5.8e-07 28.7 0.0 9e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK17412.1 - 2e-05 23.6 0.5 2.8e-05 23.1 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK17412.1 - 2.5e-05 24.2 0.5 7.2e-05 22.7 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK17412.1 - 5.9e-05 22.1 0.1 0.0001 21.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KKK17412.1 - 9.7e-05 21.5 0.1 0.00087 18.4 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KKK17412.1 - 0.00014 21.7 0.2 0.00024 21.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK17412.1 - 0.00029 19.4 0.2 0.0004 18.9 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KKK17412.1 - 0.005 16.9 0.1 0.008 16.2 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KKK17412.1 - 0.014 14.0 0.3 0.021 13.4 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 KKK17412.1 - 0.019 15.3 0.6 0.038 14.3 0.2 1.6 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KKK17412.1 - 0.022 13.6 0.2 0.032 13.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KKK17412.1 - 0.028 14.2 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KKK17412.1 - 0.04 13.9 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.2 KKK17412.1 - 0.066 12.2 1.0 0.1 11.6 0.3 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Asparaginase PF00710.15 KKK17433.1 - 1.7e-103 345.7 0.0 2.4e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 KKK17433.1 - 2.7e-14 53.2 0.1 5.3e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KKK17433.1 - 2e-11 43.0 1.8 2.5e-05 23.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KKK17433.1 - 7.8e-11 41.8 1.7 2.5e-09 37.0 0.2 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK17433.1 - 1.3e-09 38.2 1.4 6.5e-06 26.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK17433.1 - 3.7e-07 29.7 0.8 0.032 14.4 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat MTTB PF06253.6 KKK17433.1 - 0.034 11.9 0.2 0.05 11.3 0.1 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) DUF1996 PF09362.5 KKK17434.1 - 1.5e-75 253.8 0.0 1.5e-75 253.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Rifin_STEVOR PF02009.11 KKK17434.1 - 2.4 7.7 5.7 3.5 7.1 3.9 1.2 1 0 0 1 1 1 0 Rifin/stevor family Phosphoesterase PF04185.9 KKK17435.1 - 4.1e-45 154.5 0.4 7.5e-45 153.7 0.3 1.4 1 1 0 1 1 1 1 Phosphoesterase family Phosducin PF02114.11 KKK17436.1 - 2e-12 46.3 0.0 8.4e-10 37.8 0.0 2.1 2 0 0 2 2 2 2 Phosducin WD40 PF00400.27 KKK17437.1 - 1.7e-52 173.5 22.4 6.2e-09 35.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KKK17437.1 - 2.8e-05 23.9 0.0 0.08 12.6 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A RTA1 PF04479.8 KKK17478.1 - 1.4e-50 171.9 9.0 2.2e-50 171.2 6.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Orbi_NS3 PF01616.11 KKK17478.1 - 0.14 11.0 0.1 0.31 9.9 0.1 1.6 1 1 0 1 1 1 0 Orbivirus NS3 XFP_N PF09364.5 KKK17479.1 - 5.2e-147 489.3 0.0 2e-145 484.1 0.0 2.1 1 1 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 KKK17479.1 - 1.2e-69 233.4 0.1 1.9e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 KKK17479.1 - 2.3e-37 128.4 0.2 2.4e-23 82.6 0.0 2.4 1 1 1 2 2 2 2 XFP C-terminal domain TPP_enzyme_C PF02775.16 KKK17479.1 - 0.004 16.7 0.1 0.0092 15.5 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SH3_2 PF07653.12 KKK17479.1 - 0.046 13.2 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 Variant SH3 domain AAA_16 PF13191.1 KKK17480.1 - 3.9e-05 23.7 2.2 0.002 18.1 1.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KKK17480.1 - 0.0011 18.7 0.1 0.0023 17.6 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 KKK17480.1 - 0.013 14.8 0.0 0.04 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KKK17480.1 - 0.089 12.5 0.1 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glycophorin_A PF01102.13 KKK17493.1 - 0.0021 17.7 5.9 0.0034 17.1 4.1 1.3 1 0 0 1 1 1 1 Glycophorin A Epiglycanin_TR PF05647.6 KKK17493.1 - 0.014 15.1 35.3 0.014 15.1 24.4 2.0 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like Pex14_N PF04695.8 KKK17493.1 - 0.14 12.1 3.2 0.2 11.7 2.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_A12 PF04651.8 KKK17493.1 - 0.18 11.9 7.0 0.26 11.3 4.9 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein Sporozoite_P67 PF05642.6 KKK17493.1 - 0.37 8.5 11.4 0.41 8.4 7.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3074 PF11274.3 KKK17494.1 - 1.6e-43 148.4 0.0 2e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Glyco_transf_20 PF00982.16 KKK17495.1 - 6.5e-159 529.3 0.0 8.9e-159 528.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KKK17495.1 - 2.6e-37 128.0 0.0 4.1e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase zf-H2C2_2 PF13465.1 KKK17497.1 - 6.9e-06 26.0 0.4 2.1e-05 24.5 0.3 1.9 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.21 KKK17497.1 - 0.0012 19.0 0.1 0.0036 17.5 0.1 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK17497.1 - 0.0036 17.5 0.2 0.0085 16.3 0.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KKK17497.1 - 0.016 15.0 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KKK17497.1 - 0.024 14.3 1.8 0.024 14.3 1.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TIP49 PF06068.8 KKK17498.1 - 9.7e-174 577.7 3.2 1.1e-173 577.5 2.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KKK17498.1 - 8.5e-09 35.6 1.4 1.3e-05 25.4 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KKK17498.1 - 1.9e-07 30.4 1.3 5.8e-05 22.2 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 KKK17498.1 - 6e-06 25.3 0.4 1e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KKK17498.1 - 1.4e-05 25.1 0.0 0.0003 20.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK17498.1 - 7e-05 22.9 0.0 0.075 13.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KKK17498.1 - 0.00074 18.7 0.9 0.01 15.0 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KKK17498.1 - 0.00098 19.0 0.0 1.8 8.4 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.9 KKK17498.1 - 0.0028 17.3 0.1 0.37 10.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KKK17498.1 - 0.0098 15.3 0.4 0.029 13.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KKK17498.1 - 0.012 15.0 0.1 5 6.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KKK17498.1 - 0.047 13.4 2.6 0.087 12.5 0.2 2.5 3 1 0 3 3 2 0 Part of AAA domain Parvo_NS1 PF01057.12 KKK17498.1 - 0.069 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 KKK17498.1 - 0.089 12.3 0.2 0.22 11.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK17498.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 KKK17499.1 - 9.1e-79 265.1 26.1 8.5e-65 219.0 7.5 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK17499.1 - 8.5e-25 87.1 32.6 1.4e-10 40.4 3.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily OATP PF03137.15 KKK17499.1 - 2.8e-05 22.4 4.6 0.0033 15.5 1.9 2.7 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 KKK17499.1 - 0.00084 19.0 1.0 0.023 14.4 0.0 2.7 2 0 0 2 2 2 1 MFS_1 like family RNA_pol_Rpb2_6 PF00562.23 KKK17500.1 - 2.4e-118 395.2 1.0 2.6e-118 395.1 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KKK17500.1 - 2.8e-36 124.3 0.0 8.5e-34 116.2 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KKK17500.1 - 4.1e-29 100.6 0.3 1.3e-28 99.0 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KKK17500.1 - 1.7e-26 92.8 5.3 3.7e-26 91.7 3.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 KKK17500.1 - 7.5e-21 73.7 1.5 3.2e-20 71.6 0.3 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KKK17500.1 - 8e-20 70.3 0.3 3.1e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KKK17500.1 - 4.8e-12 45.6 0.2 1.1e-11 44.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 adh_short PF00106.20 KKK17501.1 - 2.3e-17 63.4 0.1 3.9e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK17501.1 - 6.4e-12 45.7 0.0 1.7e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KKK17501.1 - 6.1e-05 22.5 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK17501.1 - 9.7e-05 22.1 0.0 0.00029 20.5 0.0 1.7 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KKK17501.1 - 0.0012 18.5 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 KKK17501.1 - 0.017 14.6 0.1 0.086 12.3 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Exo_endo_phos PF03372.18 KKK17501.1 - 0.054 13.4 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family 2-Hacid_dh_C PF02826.14 KKK17501.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2764 PF10962.3 KKK17502.1 - 0.059 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) RS4NT PF08071.7 KKK17502.1 - 0.19 11.6 0.8 4.2 7.3 0.3 2.4 2 0 0 2 2 2 0 RS4NT (NUC023) domain Abhydrolase_6 PF12697.2 KKK17503.1 - 7.5e-27 94.6 0.0 9.2e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK17503.1 - 1.6e-15 57.3 0.1 1.3e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK17503.1 - 6.1e-14 51.9 0.0 9.1e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK17503.1 - 4.9e-10 39.3 0.1 7e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 KKK17503.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.4 1 1 0 1 1 1 1 Putative esterase DUF915 PF06028.6 KKK17503.1 - 0.0014 17.7 0.1 1.1 8.2 0.1 2.7 2 1 1 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 KKK17503.1 - 0.0019 18.5 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.6 KKK17503.1 - 0.0028 16.5 0.0 0.0063 15.3 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase DUF676 PF05057.9 KKK17503.1 - 0.0073 15.6 0.1 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 KKK17503.1 - 0.0094 15.5 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 KKK17503.1 - 0.011 14.1 0.0 0.029 12.8 0.0 1.6 2 0 0 2 2 2 0 Ndr family DUF2048 PF09752.4 KKK17503.1 - 0.02 13.7 0.0 0.2 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 KKK17503.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 KKK17503.1 - 0.036 13.4 0.0 8.8 5.6 0.0 2.3 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 KKK17503.1 - 0.096 11.9 0.0 0.41 9.8 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family LCAT PF02450.10 KKK17503.1 - 0.098 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GYF PF02213.11 KKK17504.1 - 5.9e-13 48.2 0.5 1.3e-12 47.1 0.3 1.6 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.9 KKK17505.1 - 8e-77 256.3 0.0 1e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Oxidored_FMN PF00724.15 KKK17506.1 - 8.2e-63 212.4 0.0 2.5e-61 207.5 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_L3 PF00297.17 KKK17531.1 - 1.5e-118 395.0 9.2 2e-118 394.5 6.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.23 KKK17531.1 - 8.5e-51 167.5 22.0 6.2e-08 31.9 0.0 10.8 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KKK17531.1 - 5.8e-44 144.5 16.7 2e-05 24.1 0.0 10.7 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 KKK17531.1 - 2e-42 142.6 19.2 2.7e-10 39.7 0.3 6.4 3 2 1 6 6 6 6 TPR repeat TPR_8 PF13181.1 KKK17531.1 - 1.7e-37 124.3 16.5 4e-05 23.0 0.6 10.4 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 KKK17531.1 - 1.1e-28 98.9 20.1 6.7e-07 29.1 0.2 7.3 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 KKK17531.1 - 1.1e-26 92.8 16.3 2.4e-06 28.0 0.0 6.8 4 2 3 8 8 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 KKK17531.1 - 8e-25 84.9 12.9 0.0019 18.2 0.1 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 KKK17531.1 - 9.5e-24 81.7 17.1 0.00011 22.4 0.0 9.9 4 2 7 11 11 11 8 Tetratricopeptide repeat TPR_7 PF13176.1 KKK17531.1 - 8.3e-22 75.2 9.8 0.0047 16.6 0.0 9.7 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KKK17531.1 - 7.2e-21 74.3 10.7 0.00012 22.3 0.0 6.9 5 2 0 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 KKK17531.1 - 1.7e-18 65.7 15.9 0.0061 16.9 0.0 10.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 KKK17531.1 - 3.5e-14 52.4 8.1 0.00064 19.5 0.0 6.5 2 1 4 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 KKK17531.1 - 7.6e-13 48.4 8.5 5.6e-08 32.8 2.1 4.0 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KKK17531.1 - 8.2e-06 25.0 15.8 0.0077 15.3 2.5 5.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.4 KKK17531.1 - 0.00068 19.5 7.2 0.38 10.6 2.2 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KKK17531.1 - 0.0068 16.5 0.1 0.98 9.5 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 KKK17531.1 - 0.061 13.6 5.9 3.2 8.0 0.1 3.6 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 KKK17531.1 - 0.13 12.2 10.4 27 4.8 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 KKK17531.1 - 0.5 10.2 16.4 3.2 7.7 1.1 5.6 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain zf-DNA_Pol PF08996.5 KKK17533.1 - 0.0023 17.3 3.4 0.54 9.6 0.3 2.2 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger DZR PF12773.2 KKK17533.1 - 0.062 13.1 4.8 1.5 8.6 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon p450 PF00067.17 KKK17534.1 - 3.8e-72 243.2 0.0 4.3e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3295 PF11702.3 KKK17535.1 - 1.1e-197 658.1 32.2 1.2e-197 657.9 22.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KKK17535.1 - 5e-12 45.1 2.4 1.2e-11 43.9 1.7 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyoxalase PF00903.20 KKK17536.1 - 1.7e-08 34.4 0.0 2.3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KKK17536.1 - 2.3e-05 24.3 0.0 6.5e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pkinase PF00069.20 KKK17537.1 - 1.2e-31 109.7 0.0 6.1e-31 107.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17537.1 - 4.9e-12 45.4 0.0 1.2e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ETF PF01012.16 KKK17538.1 - 3.2e-36 124.5 0.3 4.2e-36 124.1 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ribosomal_L20 PF00453.13 KKK17538.1 - 0.019 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 JAB PF01398.16 KKK17539.1 - 7.6e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Flavodoxin_1 PF00258.20 KKK17540.1 - 9.8e-34 116.4 0.0 2e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 KKK17540.1 - 5.2e-30 104.5 0.0 7.9e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KKK17540.1 - 2.3e-14 53.8 0.0 6.4e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KKK17540.1 - 0.00089 19.2 0.1 0.046 13.7 0.0 2.7 2 1 1 3 3 3 2 Flavodoxin domain Flavodoxin_3 PF12641.2 KKK17540.1 - 0.0012 18.2 0.0 0.0033 16.8 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.3 KKK17541.1 - 3.7e-56 190.6 7.5 5.1e-56 190.2 5.2 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 bZIP_1 PF00170.16 KKK17542.1 - 0.0015 18.4 11.4 0.003 17.4 6.7 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KKK17542.1 - 0.17 11.7 9.3 0.092 12.5 4.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper eIF-3_zeta PF05091.7 KKK17543.1 - 4e-197 655.9 0.0 4.6e-197 655.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ycf1 PF05758.7 KKK17544.1 - 0.21 9.2 0.7 0.24 9.0 0.5 1.1 1 0 0 1 1 1 0 Ycf1 DUF3121 PF11319.3 KKK17544.1 - 0.27 10.7 3.1 0.43 10.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) SNF2_N PF00176.18 KKK17545.1 - 7e-74 248.3 0.0 1.2e-73 247.5 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain TroA PF01297.12 KKK17546.1 - 6.8 5.8 13.4 0.38 9.9 1.8 3.7 2 1 0 3 3 3 0 Periplasmic solute binding protein family DctM PF06808.7 KKK17547.1 - 0.041 12.4 0.4 0.06 11.8 0.3 1.2 1 0 0 1 1 1 0 DctM-like transporters Ribosomal_L33 PF00471.15 KKK17548.1 - 0.0003 20.9 0.0 0.0004 20.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Mid2 PF04478.7 KKK17549.1 - 0.00024 20.5 1.4 0.00045 19.6 1.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Dicty_REP PF05086.7 KKK17549.1 - 0.00072 17.4 0.2 0.00086 17.2 0.1 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Alpha_GJ PF03229.8 KKK17549.1 - 0.0081 16.4 3.3 0.0081 16.4 2.3 1.8 2 0 0 2 2 2 1 Alphavirus glycoprotein J Podoplanin PF05808.6 KKK17549.1 - 0.0098 15.4 3.1 0.0098 15.4 2.2 1.5 2 0 0 2 2 2 1 Podoplanin Tox-GHH PF15636.1 KKK17549.1 - 0.011 15.3 0.1 0.027 14.1 0.1 1.6 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin TMEM154 PF15102.1 KKK17549.1 - 0.024 14.3 1.2 0.043 13.5 0.8 1.5 1 0 0 1 1 1 0 TMEM154 protein family Mucin PF01456.12 KKK17549.1 - 0.19 11.4 27.2 0.4 10.4 16.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 KKK17549.1 - 0.62 7.9 23.1 1.1 7.1 16.0 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Gly_transf_sug PF04488.10 KKK17551.1 - 3.6e-10 40.1 0.0 6.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3246 PF11596.3 KKK17551.1 - 0.00043 19.6 8.0 0.00069 18.9 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Caps_synth PF05704.7 KKK17551.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 KKK17551.1 - 0.096 11.1 0.0 1.4 7.3 0.0 2.3 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain SR-25 PF10500.4 KKK17551.1 - 0.19 11.2 0.7 0.28 10.6 0.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAN_3 PF08277.7 KKK17552.1 - 0.098 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 PAN-like domain Ribonuc_L-PSP PF01042.16 KKK17553.1 - 2.5e-22 78.9 0.0 3.1e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cellulase PF00150.13 KKK17554.1 - 5.4e-07 29.0 1.1 1.2e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TMEM154 PF15102.1 KKK17554.1 - 0.00069 19.3 0.4 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 TMEM154 protein family DUF3357 PF11837.3 KKK17554.1 - 0.0014 18.4 0.3 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3357) DUF1191 PF06697.7 KKK17554.1 - 0.0046 15.8 0.0 0.0082 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF1510 PF07423.6 KKK17554.1 - 0.049 13.0 0.1 0.049 13.0 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) EphA2_TM PF14575.1 KKK17554.1 - 0.053 13.9 0.0 0.053 13.9 0.0 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Wzy_C PF04932.10 KKK17554.1 - 0.053 13.3 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase Tetraspannin PF00335.15 KKK17554.1 - 0.055 12.7 0.7 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Tetraspanin family CcmH PF03918.9 KKK17554.1 - 0.14 11.1 0.0 0.78 8.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein zf-C2H2 PF00096.21 KKK17573.1 - 3.2e-05 23.9 29.1 0.16 12.4 0.2 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK17573.1 - 0.0014 18.8 25.4 0.93 9.9 0.2 7.1 6 1 1 7 7 7 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KKK17573.1 - 0.0032 17.5 22.2 0.28 11.3 6.1 3.7 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.2 KKK17573.1 - 0.038 13.9 4.5 13 5.8 0.0 4.2 4 0 0 4 4 4 0 Zinc-binding zf-C2H2_6 PF13912.1 KKK17573.1 - 0.072 13.0 0.2 0.072 13.0 0.1 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.2 KKK17573.1 - 0.1 12.8 22.2 0.47 10.7 0.0 5.9 6 1 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK17573.1 - 0.88 9.8 21.2 11 6.3 0.9 5.8 4 1 1 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KKK17573.1 - 1.5 9.2 0.0 1.5 9.2 0.0 5.7 5 1 1 6 6 6 0 Zinc-finger double domain zf-Dof PF02701.10 KKK17573.1 - 1.9 8.4 0.0 1.9 8.4 0.0 4.2 3 2 2 5 5 5 0 Dof domain, zinc finger zf-NADH-PPase PF09297.6 KKK17573.1 - 2.8 7.5 0.0 2.8 7.5 0.0 4.5 5 0 0 5 5 5 0 NADH pyrophosphatase zinc ribbon domain C1_4 PF07975.7 KKK17573.1 - 4.5 7.3 27.5 15 5.6 0.1 5.5 3 1 1 4 4 3 0 TFIIH C1-like domain DUF2205 PF10224.4 KKK17590.1 - 3.9e-31 106.4 3.3 3.9e-31 106.4 2.3 1.6 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 KKK17590.1 - 0.0031 15.9 4.6 0.0033 15.7 3.2 1.0 1 0 0 1 1 1 1 Transmembrane protein Spectrin PF00435.16 KKK17590.1 - 0.0073 16.5 1.0 0.012 15.9 0.7 1.3 1 0 0 1 1 1 1 Spectrin repeat DUF4140 PF13600.1 KKK17590.1 - 0.024 15.1 1.1 0.044 14.2 0.7 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KKK17590.1 - 0.025 14.1 2.5 0.024 14.2 1.8 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KKK17590.1 - 0.04 14.2 3.2 0.077 13.3 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 KKK17590.1 - 0.043 13.3 1.4 0.072 12.5 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DASH_Dam1 PF08653.5 KKK17590.1 - 0.068 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 OmpH PF03938.9 KKK17590.1 - 0.1 12.4 4.2 0.13 12.1 2.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.13 KKK17590.1 - 0.15 11.8 4.5 1 9.1 0.1 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.6 KKK17590.1 - 0.2 10.2 3.4 0.25 9.9 2.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.16 KKK17590.1 - 0.35 10.8 4.8 1.1 9.2 3.4 1.8 1 1 0 1 1 1 0 bZIP transcription factor LCD1 PF09798.4 KKK17590.1 - 1.6 6.6 8.5 0.13 10.1 3.0 1.3 2 0 0 2 2 2 0 DNA damage checkpoint protein HTH_AsnC-type PF13404.1 KKK17590.1 - 5.2 6.6 5.9 9.1 5.9 1.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain AMP-binding PF00501.23 KKK17593.1 - 2.6e-77 259.9 0.0 3.1e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK17593.1 - 7.5e-13 49.2 0.1 2.9e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HTH_DeoR PF08220.7 KKK17593.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Amidase PF01425.16 KKK17594.1 - 2e-97 326.8 0.0 2.3e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 Amidase EAP30 PF04157.11 KKK17595.1 - 6.2e-54 182.4 0.0 1.2e-53 181.6 0.0 1.4 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KKK17595.1 - 2.2e-21 75.4 0.0 1.2e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 KKK17595.1 - 0.0012 18.4 1.0 0.0012 18.4 0.7 2.6 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GRAM PF02893.15 KKK17595.1 - 0.073 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 GRAM domain zf-RanBP PF00641.13 KKK17595.1 - 0.097 11.7 12.4 0.18 10.9 0.2 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.2 KKK17595.1 - 2 8.3 5.3 0.77 9.6 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon LSM PF01423.17 KKK17616.1 - 3.5e-18 64.9 0.3 4.9e-18 64.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SH3_9 PF14604.1 KKK17616.1 - 0.4 10.2 2.1 5.6 6.6 0.0 2.7 3 0 0 3 3 3 0 Variant SH3 domain ATP13 PF12921.2 KKK17617.1 - 9.3e-26 89.6 0.0 1.6e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 KKK17617.1 - 0.0023 17.8 0.0 0.66 10.0 0.0 3.1 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 KKK17617.1 - 0.0099 16.0 0.4 23 5.5 0.0 4.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PIG-L PF02585.12 KKK17618.1 - 5.1e-25 88.4 0.0 7.2e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_hydro_16 PF00722.16 KKK17619.1 - 1.3e-34 119.1 3.8 2.1e-34 118.4 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SH3_9 PF14604.1 KKK17621.1 - 1.3e-15 56.6 0.2 2.5e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK17621.1 - 2.6e-13 49.1 0.1 4.4e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK17621.1 - 4.3e-12 45.3 0.1 7.9e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3439 PF11921.3 KKK17621.1 - 0.87 9.3 6.6 7.5 6.3 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RTC PF01137.16 KKK17622.1 - 9.2e-37 126.0 0.0 1.2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase EthD PF07110.6 KKK17624.1 - 1e-22 80.8 1.2 1.2e-22 80.6 0.8 1.0 1 0 0 1 1 1 1 EthD domain Chlor_dismutase PF06778.7 KKK17624.1 - 0.041 13.5 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Chlorite dismutase Myb_DNA-bind_6 PF13921.1 KKK17625.1 - 8.1e-05 22.6 1.2 0.0075 16.3 0.2 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK17625.1 - 0.00093 19.2 4.4 0.17 11.9 0.6 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Nucleoplasmin PF03066.10 KKK17625.1 - 0.0099 15.4 8.4 0.015 14.8 5.8 1.3 1 0 0 1 1 1 1 Nucleoplasmin RXT2_N PF08595.6 KKK17625.1 - 0.018 14.8 2.6 0.028 14.2 1.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.1 KKK17625.1 - 0.16 12.2 5.9 0.3 11.3 4.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 KKK17625.1 - 0.18 10.9 4.8 0.24 10.5 3.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 KKK17625.1 - 0.21 11.8 9.1 0.39 10.9 6.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myb_DNA-bind_5 PF13873.1 KKK17625.1 - 0.23 11.3 2.9 3 7.8 0.0 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain NOA36 PF06524.7 KKK17625.1 - 0.27 10.4 4.7 0.36 10.0 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_17 PF00332.13 KKK17626.1 - 3.2e-25 88.8 0.6 2e-24 86.1 0.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PGK PF00162.14 KKK17626.1 - 0.023 13.2 0.1 0.067 11.7 0.0 1.6 1 1 1 2 2 2 0 Phosphoglycerate kinase PAM2 PF07145.10 KKK17627.1 - 0.00031 20.0 9.1 0.077 12.5 0.0 4.7 5 0 0 5 5 5 3 Ataxin-2 C-terminal region SUR7 PF06687.7 KKK17642.1 - 4.9e-31 107.9 9.5 6.2e-31 107.6 6.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.1 KKK17642.1 - 0.019 14.8 0.6 0.068 13.0 0.1 2.2 2 1 1 3 3 3 0 SCIMP protein NfeD PF01957.13 KKK17642.1 - 0.049 13.7 2.5 0.082 13.0 0.2 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4381 PF14316.1 KKK17642.1 - 3.3 7.8 5.4 0.52 10.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Ribosomal_L34 PF00468.12 KKK17660.1 - 2.6e-16 58.9 11.9 4e-16 58.4 8.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Peptidase_M48 PF01435.13 KKK17661.1 - 9.2e-51 172.5 0.1 1.4e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.1 KKK17661.1 - 0.0092 15.2 1.2 0.024 13.9 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.6 KKK17661.1 - 0.063 12.2 1.7 0.11 11.5 0.5 1.8 2 1 0 2 2 2 0 BlaR1 peptidase M56 DUF2201_N PF13203.1 KKK17661.1 - 0.19 10.8 0.1 0.35 10.0 0.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain RNA_polI_A14 PF08203.6 KKK17662.1 - 0.027 14.6 0.0 0.094 12.9 0.0 1.9 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 EF-hand_5 PF13202.1 KKK17662.1 - 0.15 11.4 0.2 0.28 10.5 0.2 1.4 1 0 0 1 1 1 0 EF hand WD40 PF00400.27 KKK17663.1 - 1.1e-70 231.2 38.7 1.2e-08 34.5 0.1 12.2 11 2 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 KKK17663.1 - 2.4e-44 150.4 0.0 4e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KKK17663.1 - 4.1e-10 38.4 9.4 0.011 13.9 0.8 5.8 2 2 2 5 5 5 5 Nucleoporin Nup120/160 DUF1921 PF09081.5 KKK17663.1 - 1.5 8.8 5.0 8.3 6.4 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1921) G-patch_2 PF12656.2 KKK17664.1 - 6.2e-29 99.6 0.0 4.1e-28 97.0 0.0 2.5 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 KKK17664.1 - 4.4e-05 23.1 0.2 9.8e-05 22.0 0.1 1.7 1 0 0 1 1 1 1 G-patch domain Med13_C PF06333.7 KKK17664.1 - 2.2 6.7 4.3 5.3 5.4 3.0 1.6 1 1 0 1 1 1 0 Mediator complex subunit 13 C-terminal UCH PF00443.24 KKK17665.1 - 5.9e-23 81.3 0.0 2e-21 76.3 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KKK17665.1 - 1.1e-11 44.7 0.1 2.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KKK17665.1 - 0.00015 21.2 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HSA PF07529.8 KKK17667.1 - 3.2e-22 78.1 2.5 3.2e-22 78.1 1.7 3.6 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 KKK17667.1 - 2.8e-16 59.3 2.0 3.2e-16 59.1 0.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK17667.1 - 0.0054 16.7 0.7 0.017 15.1 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain GTP_EFTU PF00009.22 KKK17668.1 - 2.6e-37 128.1 0.0 4.4e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KKK17668.1 - 5.2e-36 122.5 0.4 1.2e-35 121.3 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KKK17668.1 - 1e-11 44.7 0.1 2.7e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 WD40 PF00400.27 KKK17668.1 - 1e-07 31.5 0.0 0.14 12.0 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat MMR_HSR1 PF01926.18 KKK17668.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Proteasome PF00227.21 KKK17669.1 - 1.5e-38 131.9 0.0 2e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 KKK17670.1 - 7.1e-32 108.1 11.5 1.7e-08 34.0 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KKK17670.1 - 0.0007 17.8 0.5 4 5.4 0.0 4.1 3 1 1 5 5 5 4 Nucleoporin Nup120/160 Fungal_trans PF04082.13 KKK17671.1 - 0.00055 18.8 0.1 0.00084 18.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy PF03171.15 KKK17672.1 - 1.9e-05 24.8 0.0 4.8e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-H2C2_2 PF13465.1 KKK17673.1 - 1.8e-05 24.7 3.3 1.8e-05 24.7 2.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 KKK17673.1 - 2.6e-05 24.2 19.3 2.8e-05 24.1 1.9 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK17673.1 - 0.0013 18.8 0.7 0.0033 17.5 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KKK17673.1 - 0.0015 18.7 0.7 0.0015 18.7 0.5 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-TRAF PF02176.13 KKK17673.1 - 0.17 12.2 6.2 0.24 11.7 1.5 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger adh_short_C2 PF13561.1 KKK17676.1 - 3.1e-32 112.2 0.0 3.5e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK17676.1 - 2.8e-27 95.6 0.3 3.5e-27 95.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK17676.1 - 6.3e-14 52.0 0.1 8.5e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Death PF00531.17 KKK17676.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Death domain FAD_binding_3 PF01494.14 KKK17677.1 - 1e-70 238.6 0.0 1.3e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KKK17677.1 - 1.1e-31 109.7 0.0 2.2e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 KKK17677.1 - 0.0028 16.6 0.0 0.032 13.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK17677.1 - 0.0093 16.3 0.0 0.04 14.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK17677.1 - 0.022 13.7 0.1 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KKK17677.1 - 0.099 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KKK17677.1 - 0.11 10.7 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Thi4 PF01946.12 KKK17677.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PagL PF09411.5 KKK17678.1 - 0.94 9.5 5.0 2 8.5 0.1 2.9 2 1 0 3 3 3 0 Lipid A 3-O-deacylase (PagL) Tannase PF07519.6 KKK17679.1 - 8.4e-95 318.2 0.0 1.2e-94 317.6 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 KKK17679.1 - 0.0019 17.8 0.0 0.004 16.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK17679.1 - 0.0032 17.3 0.0 0.014 15.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF866 PF05907.8 KKK17680.1 - 8.4e-30 103.3 1.4 1e-20 73.8 0.6 2.2 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) LSM PF01423.17 KKK17680.1 - 1.7e-16 59.4 0.1 3e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain MFS_1 PF07690.11 KKK17681.1 - 4.4e-26 91.4 53.7 2e-25 89.2 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK17681.1 - 9.6e-06 24.0 2.4 2e-05 22.9 1.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPR_11 PF13414.1 KKK17682.1 - 3e-15 55.6 1.4 3.9e-06 26.4 0.0 4.2 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 KKK17682.1 - 9.3e-14 50.1 2.1 0.0013 18.4 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 KKK17682.1 - 2.8e-11 42.5 2.5 0.00035 20.0 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK17682.1 - 1e-08 35.6 12.7 0.041 14.5 0.3 6.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KKK17682.1 - 2e-06 27.9 11.5 3.6 8.4 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KKK17682.1 - 3.6e-06 27.2 4.8 1.9 8.8 0.3 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KKK17682.1 - 3.7e-06 26.7 8.6 0.22 11.5 0.3 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK17682.1 - 0.0028 17.3 0.0 8.6 6.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KKK17682.1 - 0.085 12.7 8.1 3.9 7.4 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KKK17682.1 - 0.21 12.1 14.9 0.72 10.4 0.2 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat p450 PF00067.17 KKK17683.1 - 3.5e-75 253.3 0.0 6.5e-75 252.4 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 DRMBL PF07522.9 KKK17683.1 - 3.3e-34 117.2 0.0 7.2e-34 116.1 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KKK17683.1 - 0.00031 20.3 0.0 0.00072 19.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Zn_clus PF00172.13 KKK17684.1 - 8.1e-09 35.2 7.3 3.7e-08 33.1 5.1 2.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK17684.1 - 1e-05 24.5 0.2 1.9e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain OPT PF03169.10 KKK17685.1 - 7.3e-172 573.0 51.1 4.3e-170 567.2 35.4 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF754 PF05449.6 KKK17685.1 - 0.07 13.1 1.9 0.27 11.2 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF754) TcdA_TcdB_pore PF12920.2 KKK17685.1 - 0.2 9.5 0.0 0.29 9.0 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain NADH_B2 PF14813.1 KKK17685.1 - 0.44 10.2 9.7 6 6.6 0.1 3.8 3 0 0 3 3 3 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Citrate_synt PF00285.16 KKK17686.1 - 2.8e-79 266.4 0.1 7e-79 265.1 0.0 1.6 2 0 0 2 2 2 1 Citrate synthase MFS_1 PF07690.11 KKK17686.1 - 8.3e-45 153.0 23.5 8.4e-45 153.0 14.2 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK17686.1 - 3e-13 49.1 3.1 3e-13 49.1 2.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KKK17686.1 - 3e-05 22.4 2.9 3e-05 22.4 2.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KKK17686.1 - 0.02 14.6 5.2 0.066 13.0 0.3 3.6 3 1 0 3 3 3 0 MFS_1 like family DUF791 PF05631.9 KKK17686.1 - 0.12 11.0 4.8 0.052 12.2 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF791) DUF3353 PF11833.3 KKK17686.1 - 0.87 9.0 5.2 1.7 8.0 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) GFA PF04828.9 KKK17687.1 - 2.9e-19 68.8 0.0 4.2e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-B_box PF00643.19 KKK17687.1 - 0.13 12.1 1.8 16 5.4 0.5 2.6 2 0 0 2 2 2 0 B-box zinc finger Nudix_N_2 PF14803.1 KKK17687.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.9 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 KKK17687.1 - 0.27 10.7 0.1 0.27 10.7 0.0 2.5 4 1 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KKK17687.1 - 0.55 9.5 0.0 0.55 9.5 0.0 2.9 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 KKK17687.1 - 0.71 9.7 5.2 1.1 9.0 1.9 2.5 2 1 0 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.1 KKK17687.1 - 9.1 6.6 7.1 11 6.4 2.1 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar PAS_9 PF13426.1 KKK17688.1 - 8e-20 71.1 0.0 7e-17 61.7 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KKK17688.1 - 9.8e-05 22.3 0.9 0.24 11.4 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 KKK17688.1 - 0.00097 18.9 0.0 0.00097 18.9 0.0 3.5 4 0 0 4 4 4 1 PAS fold Spore_coat_CotO PF14153.1 KKK17688.1 - 0.0075 15.7 7.5 0.012 15.0 5.2 1.3 1 0 0 1 1 1 1 Spore coat protein CotO DUF4259 PF14078.1 KKK17688.1 - 0.34 11.4 6.4 0.76 10.2 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) MCPVI PF02993.9 KKK17688.1 - 1.1 9.3 5.7 2.2 8.3 3.9 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Hid1 PF12722.2 KKK17688.1 - 1.2 6.7 7.8 1.7 6.2 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3947 PF13135.1 KKK17688.1 - 9.2 6.5 14.2 29 4.9 9.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) ATG22 PF11700.3 KKK17689.1 - 8.8e-180 598.2 15.2 1e-179 598.0 10.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KKK17689.1 - 3.9e-05 22.5 21.9 3.9e-05 22.5 15.2 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily BT1 PF03092.11 KKK17689.1 - 0.00017 20.4 4.6 0.0003 19.6 3.2 1.4 1 0 0 1 1 1 1 BT1 family Zn_clus PF00172.13 KKK17690.1 - 4.5e-08 32.8 11.0 4.5e-08 32.8 7.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP PF01161.15 KKK17691.1 - 1.2e-09 38.1 0.2 2e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Mucin PF01456.12 KKK17691.1 - 0.074 12.8 19.7 0.1 12.3 13.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein PBP PF01161.15 KKK17692.1 - 1.3e-19 70.4 0.0 1.7e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein 14-3-3 PF00244.15 KKK17694.1 - 2.6e-111 370.3 6.2 3e-111 370.1 4.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF885 PF05960.6 KKK17694.1 - 0.94 8.5 5.0 0.15 11.1 0.9 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) IATP PF04568.7 KKK17695.1 - 2.1e-25 88.6 0.5 2.4e-25 88.4 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 KKK17695.1 - 0.0086 15.0 0.6 0.0086 15.0 0.4 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 zf-MIZ PF02891.15 KKK17696.1 - 3.7e-12 45.5 0.2 6.8e-12 44.7 0.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KKK17696.1 - 0.0013 18.1 0.1 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nsp1_C PF05064.8 KKK17697.1 - 1.3e-42 144.1 1.1 1.3e-42 144.1 0.8 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KKK17697.1 - 5.4e-07 29.8 41.4 5.4e-07 29.8 28.7 6.5 1 1 4 5 5 3 3 Nucleoporin FG repeat region SGT1 PF07093.6 KKK17697.1 - 0.14 10.5 4.1 0.19 10.0 2.9 1.1 1 0 0 1 1 1 0 SGT1 protein DUF3584 PF12128.3 KKK17697.1 - 0.18 9.0 7.3 0.28 8.4 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Med9 PF07544.8 KKK17697.1 - 0.18 11.5 3.4 37 4.1 0.3 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.4 KKK17697.1 - 0.2 11.7 2.4 2.8 8.1 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 KKK17697.1 - 0.31 10.0 6.8 0.52 9.3 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 MCPsignal PF00015.16 KKK17697.1 - 0.75 9.2 7.0 2.4 7.6 1.6 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4200 PF13863.1 KKK17697.1 - 0.82 9.6 8.7 0.11 12.4 3.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 KKK17697.1 - 0.84 8.0 6.8 0.62 8.4 0.8 1.9 1 1 1 2 2 2 0 AAA domain Laminin_II PF06009.7 KKK17697.1 - 1.4 8.7 5.5 9.1 6.0 0.4 2.6 2 1 0 2 2 2 0 Laminin Domain II MscS_porin PF12795.2 KKK17697.1 - 1.4 8.1 10.7 0.64 9.2 1.2 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ERM PF00769.14 KKK17697.1 - 1.4 8.3 8.8 0.33 10.4 3.4 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.7 KKK17697.1 - 1.9 8.2 4.1 2.1 8.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 KKK17697.1 - 2.1 6.6 4.9 3.4 5.9 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CENP-Q PF13094.1 KKK17697.1 - 6.1 6.8 9.1 22 5.0 5.8 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2414 PF10309.4 KKK17699.1 - 3.9e-24 84.0 0.0 6.1e-24 83.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF3439 PF11921.3 KKK17699.1 - 0.14 11.9 0.4 0.35 10.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_transf_41 PF13844.1 KKK17700.1 - 4.5e-100 334.8 0.0 7.9e-51 172.4 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 KKK17700.1 - 5.7e-19 67.5 18.6 2.6e-07 30.1 0.2 5.0 5 0 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 KKK17700.1 - 3.1e-18 64.5 10.5 4.9e-05 22.7 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 KKK17700.1 - 6.2e-14 50.7 17.8 0.0056 16.4 0.0 6.7 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KKK17700.1 - 4.5e-13 48.9 11.5 3.9e-07 29.8 0.6 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK17700.1 - 4.8e-10 39.1 14.2 0.0071 16.8 0.0 6.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KKK17700.1 - 5.5e-10 38.6 4.5 0.23 11.7 0.1 5.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK17700.1 - 3.6e-09 37.0 21.1 0.0024 18.4 1.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK17700.1 - 1.8e-08 33.5 6.7 0.073 12.8 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK17700.1 - 1.8e-06 28.1 8.7 0.0064 16.8 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK17700.1 - 2.7e-06 26.7 8.3 0.16 11.8 0.1 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KKK17700.1 - 0.00024 20.9 20.9 0.049 13.5 0.1 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_5 PF12688.2 KKK17700.1 - 0.0044 17.0 1.7 0.048 13.6 0.1 2.9 3 0 0 3 3 3 1 Tetratrico peptide repeat TPR_15 PF13429.1 KKK17700.1 - 0.0058 15.7 0.3 0.41 9.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK17700.1 - 0.0077 16.6 6.0 17 6.1 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK17700.1 - 0.081 12.7 9.0 0.087 12.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 KKK17700.1 - 0.28 10.5 0.0 0.94 8.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.12 KKK17700.1 - 0.74 10.1 12.4 2.1 8.6 0.0 4.2 5 0 0 5 5 5 0 Bacterial transcriptional activator domain DUF3638 PF12340.3 KKK17701.1 - 2.4e-97 324.4 0.0 4.3e-97 323.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KKK17701.1 - 2.3e-15 55.4 0.0 6.7e-15 53.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) Rrf2 PF02082.15 KKK17702.1 - 0.019 15.0 0.0 0.058 13.5 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator LacI PF00356.16 KKK17702.1 - 0.02 14.4 0.5 0.057 13.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family FtsQ PF03799.10 KKK17702.1 - 0.08 13.1 0.2 16 5.6 0.0 2.6 2 0 0 2 2 2 0 Cell division protein FtsQ HTH_Crp_2 PF13545.1 KKK17702.1 - 0.1 12.4 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Scytalone_dh PF02982.9 KKK17703.1 - 2.7e-62 209.0 0.6 1.4e-48 164.5 0.1 2.0 2 0 0 2 2 2 2 Scytalone dehydratase SnoaL_4 PF13577.1 KKK17703.1 - 1.6e-05 24.8 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Pkinase PF00069.20 KKK17705.1 - 1e-64 218.2 0.0 1.2e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17705.1 - 7.7e-26 90.7 0.0 9.5e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK17705.1 - 5.2e-07 28.9 0.0 2.1e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KKK17705.1 - 0.0041 16.8 0.1 0.021 14.5 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK17705.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 KKK17706.1 - 3.5e-83 277.7 0.0 6.1e-83 276.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KKK17706.1 - 4e-64 216.2 0.0 6e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G like OPT PF03169.10 KKK17707.1 - 5.8e-110 368.5 37.7 6.6e-110 368.3 26.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PH PF00169.24 KKK17708.1 - 0.0025 17.9 0.0 0.0059 16.7 0.0 1.7 1 0 0 1 1 1 1 PH domain RskA PF10099.4 KKK17708.1 - 0.012 15.3 3.8 0.026 14.2 2.6 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Pkinase PF00069.20 KKK17716.1 - 6e-30 104.2 0.0 6.7e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17716.1 - 5.2e-21 74.8 0.0 5.8e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 KKK17716.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ABC1 family UBA_4 PF14555.1 KKK17717.1 - 1.7e-14 53.0 0.1 3.6e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 KKK17717.1 - 3.1e-14 52.7 0.0 5.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 KKK17717.1 - 4.4e-06 26.6 0.0 2.6e-05 24.1 0.0 2.3 3 0 0 3 3 3 1 UBX domain Thioredoxin_2 PF13098.1 KKK17717.1 - 0.0017 18.4 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.10 KKK17717.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 AAA PF00004.24 KKK17718.1 - 5.3e-13 49.3 0.0 1.5e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK17718.1 - 8.4e-13 48.7 2.2 1.9e-12 47.5 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK17718.1 - 2.7e-12 46.9 0.1 8e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.6 KKK17718.1 - 1.8e-05 24.3 0.0 6.5e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 CDC6, C terminal DUF2075 PF09848.4 KKK17718.1 - 0.0023 16.9 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 KKK17718.1 - 0.0045 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_11 PF13086.1 KKK17718.1 - 0.0091 15.5 0.0 0.038 13.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KKK17718.1 - 0.014 14.3 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 KKK17718.1 - 0.018 14.7 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KKK17718.1 - 0.021 14.7 0.0 0.073 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KKK17718.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 NTPase PIF1 PF05970.9 KKK17718.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase TIP49 PF06068.8 KKK17718.1 - 0.031 13.0 0.0 0.054 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_19 PF13245.1 KKK17718.1 - 0.033 13.9 0.1 0.095 12.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KKK17718.1 - 0.041 14.1 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_5 PF07728.9 KKK17718.1 - 0.052 13.2 0.0 0.15 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KKK17718.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK17718.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain SLAC1 PF03595.12 KKK17759.1 - 1.5e-110 368.9 53.5 1.6e-110 368.8 37.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_28 PF00295.12 KKK17760.1 - 1.1e-29 103.4 4.1 1.1e-29 103.4 2.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 KKK17760.1 - 1.4e-08 35.1 9.0 1.4e-08 35.1 6.2 2.7 2 1 1 3 3 3 1 Pectate lyase superfamily protein MFS_1 PF07690.11 KKK17761.1 - 3.3e-23 81.9 40.5 3.9e-12 45.5 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK17761.1 - 1.6e-15 56.6 18.5 1.1e-12 47.3 2.2 2.8 1 1 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.13 KKK17762.1 - 1.5e-35 122.3 2.7 1.5e-19 69.9 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17762.1 - 6.2e-16 58.0 27.5 2.3e-09 37.0 7.7 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_synt_2f PF02092.12 KKK17762.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit UDPGP PF01704.13 KKK17763.1 - 8.4e-183 607.6 0.3 9.7e-183 607.4 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.8 KKK17763.1 - 0.012 15.4 0.2 0.055 13.3 0.0 2.1 3 0 0 3 3 3 0 Pilus assembly protein, PilO DUF4301 PF14134.1 KKK17763.1 - 0.038 12.5 0.1 0.096 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) C2 PF00168.25 KKK17764.1 - 2.3e-63 210.0 0.3 1.2e-17 63.5 0.0 5.5 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 KKK17764.1 - 0.0094 16.0 0.0 0.12 12.4 0.0 2.8 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) FKBP_C PF00254.23 KKK17764.1 - 0.028 14.4 0.2 0.17 11.9 0.0 2.4 3 0 0 3 3 3 0 FKBP-type peptidyl-prolyl cis-trans isomerase B56 PF01603.15 KKK17764.1 - 0.075 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Golgin_A5 PF09787.4 KKK17765.1 - 0.00067 18.2 0.9 0.00068 18.2 0.6 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF3439 PF11921.3 KKK17765.1 - 0.0011 18.6 3.5 0.0018 17.9 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) IncA PF04156.9 KKK17765.1 - 0.0033 17.0 2.2 0.004 16.7 1.5 1.1 1 0 0 1 1 1 1 IncA protein Atg14 PF10186.4 KKK17765.1 - 0.0055 15.6 0.8 0.0066 15.4 0.6 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin PF00804.20 KKK17765.1 - 0.036 14.2 1.5 0.05 13.7 1.0 1.3 1 0 0 1 1 1 0 Syntaxin Dicty_REP PF05086.7 KKK17765.1 - 0.045 11.5 5.1 0.074 10.7 3.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tropomyosin PF00261.15 KKK17765.1 - 0.047 12.7 3.5 0.065 12.3 2.4 1.2 1 0 0 1 1 1 0 Tropomyosin MCR_alpha PF02249.12 KKK17765.1 - 0.053 13.5 0.5 0.069 13.1 0.3 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Flu_PA PF00603.12 KKK17765.1 - 0.066 11.2 1.1 0.073 11.0 0.7 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA DUF1779 PF08680.5 KKK17765.1 - 0.19 11.5 4.2 0.28 11.0 2.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1779) Striatin PF08232.7 KKK17765.1 - 0.21 11.8 4.0 0.54 10.5 2.3 1.8 1 1 1 2 2 2 0 Striatin family DivIC PF04977.10 KKK17765.1 - 0.39 10.2 1.9 16 5.0 0.3 2.2 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.6 KKK17765.1 - 0.45 10.2 6.2 0.1 12.4 1.8 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SSP160 PF06933.6 KKK17765.1 - 0.76 7.6 9.8 0.99 7.3 6.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tropomyosin_1 PF12718.2 KKK17765.1 - 0.83 9.4 7.9 0.72 9.7 4.8 1.5 1 1 0 1 1 1 0 Tropomyosin like Leo1 PF04004.8 KKK17766.1 - 1.8e-32 112.4 0.0 2.9e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Leo1-like protein DUF2890 PF11081.3 KKK17766.1 - 1.3 9.0 9.3 2.7 8.0 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Zn_clus PF00172.13 KKK17767.1 - 6.5e-09 35.5 8.5 1.9e-08 34.0 5.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob1_phocein PF03637.12 KKK17768.1 - 1.1e-30 106.6 3.4 1.5e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family BOP1NT PF08145.7 KKK17769.1 - 1.4e-106 356.0 7.3 2e-106 355.5 5.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KKK17769.1 - 2e-26 90.8 9.6 6.9e-11 41.5 0.1 6.2 7 1 0 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.1 KKK17769.1 - 0.052 13.8 1.9 3.3 8.1 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain Npa1 PF11707.3 KKK17770.1 - 1.8e-105 352.6 0.1 3.8e-105 351.5 0.1 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 KKK17770.1 - 0.012 15.8 0.1 0.05 13.7 0.0 2.2 2 0 0 2 2 2 0 Creb binding Arm PF00514.18 KKK17770.1 - 0.073 12.9 0.0 1.6 8.7 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF221 PF02714.10 KKK17771.1 - 4e-113 377.5 27.4 3.2e-111 371.3 12.5 2.9 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 KKK17771.1 - 8.9e-46 155.3 3.9 8.9e-46 155.3 2.7 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KKK17771.1 - 2.8e-33 113.6 0.5 6.3e-33 112.5 0.1 1.7 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KKK17771.1 - 1.5e-21 76.6 0.3 2.8e-21 75.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Baculo_E56 PF04639.7 KKK17771.1 - 0.16 10.6 0.0 0.16 10.6 0.0 1.8 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope Amnionless PF14828.1 KKK17771.1 - 0.22 9.9 0.0 6.9 5.0 0.0 2.2 2 0 0 2 2 2 0 Amnionless DUF4519 PF15012.1 KKK17771.1 - 2.4 8.1 7.0 1.1 9.2 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Rifin_STEVOR PF02009.11 KKK17771.1 - 8.1 5.9 7.3 54 3.2 0.0 2.9 3 0 0 3 3 3 0 Rifin/stevor family DUF912 PF06024.7 KKK17771.1 - 8.4 6.5 10.6 7.3 6.7 0.0 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) rve PF00665.21 KKK17772.1 - 0.032 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain VHP PF02209.14 KKK17772.1 - 0.068 12.8 0.1 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Villin headpiece domain Cation_ATPase_C PF00689.16 KKK17773.1 - 5.1e-20 71.7 8.1 6.1e-20 71.5 5.6 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus CAAD PF14159.1 KKK17773.1 - 0.63 9.7 5.1 0.5 10.0 1.4 2.0 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Ras PF00071.17 KKK17774.1 - 2.3e-56 189.6 0.0 2.6e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK17774.1 - 8.3e-16 58.5 0.0 1.5e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK17774.1 - 2.9e-07 29.9 0.0 4.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK17774.1 - 6.7e-05 22.3 0.0 0.00031 20.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KKK17774.1 - 0.0051 16.0 0.0 0.0094 15.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KKK17774.1 - 0.0077 15.3 0.0 0.0099 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.17 KKK17774.1 - 0.025 13.4 0.1 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 KKK17774.1 - 0.049 13.1 0.0 11 5.5 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KOW PF00467.24 KKK17775.1 - 0.036 13.8 0.7 0.066 12.9 0.5 1.5 1 0 0 1 1 1 0 KOW motif Complex1_LYR PF05347.10 KKK17775.1 - 0.13 12.0 6.1 6.2 6.7 1.9 2.5 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Mpv17_PMP22 PF04117.7 KKK17776.1 - 5.4e-19 67.5 0.4 5.4e-19 67.5 0.3 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family MFS_1 PF07690.11 KKK17777.1 - 1.2e-40 139.3 44.0 1.2e-40 139.3 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK17777.1 - 2.8e-09 36.0 12.7 2.8e-09 36.0 8.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter FTA4 PF13093.1 KKK17777.1 - 0.15 11.4 0.3 0.22 10.9 0.2 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Anillin PF08174.6 KKK17778.1 - 1.6e-33 115.7 0.3 4.2e-33 114.3 0.2 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KKK17778.1 - 9.7e-10 38.5 0.0 3e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KKK17778.1 - 0.04 14.1 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DEAD PF00270.24 KKK17779.1 - 3.7e-33 114.3 0.1 1.7e-32 112.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK17779.1 - 4.4e-16 58.5 0.0 1.3e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KKK17779.1 - 0.00023 20.0 0.0 0.00037 19.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KKK17779.1 - 0.0013 18.5 0.0 0.0046 16.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIE_alpha PF02002.12 KKK17780.1 - 2.1e-18 65.7 0.0 5.9e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.5 KKK17780.1 - 0.041 13.8 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 KKK17780.1 - 0.053 12.8 2.3 1.2 8.4 1.6 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding HTH_Crp_2 PF13545.1 KKK17780.1 - 0.13 12.1 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PseudoU_synth_1 PF01416.15 KKK17781.1 - 4.4e-17 62.4 0.1 1.3e-08 35.1 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase SET PF00856.23 KKK17782.1 - 8.5e-10 39.1 0.0 1.9e-08 34.7 0.0 2.8 2 0 0 2 2 2 1 SET domain Ribosomal_L14 PF00238.14 KKK17783.1 - 7.9e-47 158.0 2.7 8.8e-47 157.8 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Rotamase PF00639.16 KKK17784.1 - 4.1e-24 85.1 0.0 5.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KKK17784.1 - 4.7e-16 59.1 0.0 5.2e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KKK17784.1 - 6.3e-06 26.8 0.0 7.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 KKK17784.1 - 0.01 15.6 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 MAM domain RNA_POL_M_15KD PF02150.11 KKK17785.1 - 2e-10 40.1 1.5 2e-10 40.1 1.0 2.7 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 KKK17785.1 - 0.011 15.7 3.3 0.5 10.3 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme CytoC_RC PF02276.13 KKK17785.1 - 0.13 11.3 2.4 0.27 10.2 1.6 1.5 1 1 1 2 2 2 0 Photosynthetic reaction centre cytochrome C subunit C1_1 PF00130.17 KKK17785.1 - 0.85 9.3 6.0 2.8 7.7 0.4 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 KKK17785.1 - 0.92 9.4 7.0 3 7.8 0.6 2.4 2 0 0 2 2 2 0 FYVE zinc finger APH PF01636.18 KKK17786.1 - 1e-06 28.6 0.1 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Tom37_C PF11801.3 KKK17787.1 - 8.1e-43 146.2 0.1 1.7e-42 145.1 0.0 1.6 2 0 0 2 2 2 1 Tom37 C-terminal domain Tom37 PF10568.4 KKK17787.1 - 5.9e-27 93.7 1.0 5.1e-26 90.7 0.0 2.9 4 0 0 4 4 4 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 KKK17787.1 - 7.4e-06 25.7 0.1 3.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Hist_deacetyl PF00850.14 KKK17788.1 - 8.6e-78 261.7 0.3 1.2e-77 261.3 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF2417 PF10329.4 KKK17820.1 - 1.4e-88 296.2 0.8 2.1e-88 295.6 0.5 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KKK17820.1 - 5.3e-09 36.2 0.1 9.6e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK17821.1 - 5.7e-22 78.7 0.7 7.8e-22 78.2 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK17821.1 - 3.4e-08 33.3 0.0 5.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK17821.1 - 0.00072 19.1 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 KKK17821.1 - 0.097 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Glyco_hydro_18 PF00704.23 KKK17822.1 - 5e-65 220.1 0.0 5.6e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 KKK17822.1 - 0.0099 15.5 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) DUF3712 PF12505.3 KKK17823.1 - 1.8e-33 115.2 0.7 4.9e-33 113.8 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) Cu-oxidase_3 PF07732.10 KKK17823.1 - 0.013 15.2 0.1 0.032 13.9 0.1 1.7 1 0 0 1 1 1 0 Multicopper oxidase Flavodoxin_1 PF00258.20 KKK17824.1 - 4.5e-10 39.6 0.0 6.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 KKK17824.1 - 1.6e-08 34.2 0.0 2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KKK17824.1 - 4.9e-07 29.4 0.0 6.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 KKK17824.1 - 0.018 14.3 0.1 0.041 13.2 0.1 1.6 1 1 0 1 1 1 0 Flavodoxin Flavodoxin_5 PF12724.2 KKK17824.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin domain zf-CCCH PF00642.19 KKK17825.1 - 5.1e-19 67.5 28.9 5.4e-07 29.1 0.8 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KKK17825.1 - 0.0084 15.5 3.6 0.94 9.0 0.1 3.1 2 0 0 2 2 2 2 Putative zinc-finger domain Sel1 PF08238.7 KKK17826.1 - 7.1e-15 55.0 12.2 7.3e-05 23.2 3.8 4.4 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 KKK17826.1 - 0.19 11.3 4.9 16 5.2 2.3 2.7 2 1 0 2 2 2 0 TPR repeat NPL4 PF05021.10 KKK17827.1 - 6.5e-125 416.3 0.0 8.1e-125 416.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KKK17827.1 - 2.3e-72 241.4 0.1 3.6e-72 240.8 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KKK17827.1 - 0.011 16.0 0.0 0.088 13.1 0.0 2.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF2080 PF09853.4 KKK17827.1 - 0.039 13.6 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) eIF-3_zeta PF05091.7 KKK17827.1 - 0.2 10.2 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3752 PF12572.3 KKK17828.1 - 3.2e-42 144.2 11.7 3.2e-42 144.2 8.1 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) DUF4407 PF14362.1 KKK17828.1 - 0.099 11.5 3.0 0.13 11.2 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.1 KKK17828.1 - 4.1 7.2 5.5 8.7 6.1 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Methyltransf_11 PF08241.7 KKK17829.1 - 0.0084 16.5 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain SAP PF02037.22 KKK17830.1 - 4.5e-12 45.1 0.8 8.8e-11 41.0 0.0 2.4 2 0 0 2 2 2 1 SAP domain CDC27 PF09507.5 KKK17830.1 - 1.1 8.3 16.4 1.2 8.2 11.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 WD40 PF00400.27 KKK17831.1 - 7.5e-55 180.9 20.3 3.6e-10 39.3 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KKK17831.1 - 6e-47 159.3 0.0 8.8e-47 158.7 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 KKK17831.1 - 9.4e-07 28.3 0.0 2.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 KKK17831.1 - 0.00083 17.6 4.7 0.036 12.1 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KKK17831.1 - 0.0089 14.8 0.1 4.8 5.8 0.0 3.9 3 1 1 4 4 4 1 Nup133 N terminal like DUF3550 PF12070.3 KKK17831.1 - 0.077 11.7 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3550/UPF0682) F_actin_cap_B PF01115.12 KKK17832.1 - 1.4e-89 299.4 0.0 1.6e-75 253.4 0.0 2.2 1 1 1 2 2 2 2 F-actin capping protein, beta subunit ResIII PF04851.10 KKK17832.1 - 3.1e-19 69.5 0.0 6.9e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK17832.1 - 1.2e-18 66.7 0.1 3.9e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK17832.1 - 1.5e-18 66.8 0.0 4.6e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK17832.1 - 0.022 14.8 0.0 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Med11 PF10280.4 KKK17833.1 - 3.5e-37 127.0 0.0 4.4e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Med29 PF11568.3 KKK17833.1 - 0.00048 20.2 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 29 PTS_IIA PF02255.11 KKK17833.1 - 0.077 12.8 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit MA3 PF02847.12 KKK17834.1 - 5.8e-26 90.4 0.0 1.9e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 KKK17834.1 - 1.5e-25 89.8 0.9 2.3e-25 89.2 0.2 1.7 2 0 0 2 2 2 1 MIF4G domain WD40 PF00400.27 KKK17835.1 - 0.13 12.2 1.3 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat DPM2 PF07297.7 KKK17836.1 - 5e-35 119.6 1.6 5.8e-35 119.4 1.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4083 PF13314.1 KKK17836.1 - 0.00018 21.2 0.2 0.00018 21.2 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) PIG-P PF08510.7 KKK17836.1 - 0.0086 15.7 1.4 0.011 15.4 0.9 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 KKK17836.1 - 0.27 11.1 3.0 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) FixQ PF05545.6 KKK17836.1 - 0.96 9.1 4.8 13 5.5 2.0 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF1469 PF07332.6 KKK17836.1 - 1.5 8.5 6.3 2.5 7.8 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) HD PF01966.17 KKK17838.1 - 1.3e-06 28.4 1.0 4.7e-06 26.6 0.1 2.0 2 0 0 2 2 2 1 HD domain AAA PF00004.24 KKK17839.1 - 8.1e-48 161.9 0.0 1.9e-42 144.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KKK17839.1 - 3.8e-07 29.6 0.0 4.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 KKK17839.1 - 3.4e-06 27.1 0.0 3.6e-05 23.8 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KKK17839.1 - 4.9e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KKK17839.1 - 2.2e-05 24.6 0.1 0.00092 19.3 0.0 3.3 2 1 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 KKK17839.1 - 5.7e-05 23.1 0.0 0.067 13.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 KKK17839.1 - 0.00018 21.2 0.1 0.00087 19.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.20 KKK17839.1 - 0.00054 19.8 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 Bromodomain AAA_14 PF13173.1 KKK17839.1 - 0.0016 18.3 0.0 0.005 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK17839.1 - 0.0025 18.6 1.3 0.011 16.5 0.0 2.8 3 0 0 3 3 1 1 AAA domain AAA_25 PF13481.1 KKK17839.1 - 0.0029 17.0 0.0 0.0099 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KKK17839.1 - 0.0036 17.4 0.0 0.0089 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KKK17839.1 - 0.005 16.5 0.0 0.023 14.4 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KKK17839.1 - 0.0071 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KKK17839.1 - 0.012 14.3 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 KKK17839.1 - 0.013 15.7 0.0 0.057 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KKK17839.1 - 0.024 14.2 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KKK17839.1 - 0.032 13.2 0.0 0.064 12.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KKK17839.1 - 0.032 14.2 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK17839.1 - 0.037 13.2 0.0 0.095 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KKK17839.1 - 0.043 14.1 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 1 0 ABC transporter Sigma54_activat PF00158.21 KKK17839.1 - 0.048 13.1 0.0 1.2 8.5 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 KKK17839.1 - 0.056 13.1 0.0 0.18 11.4 0.0 1.9 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 KKK17839.1 - 0.075 11.9 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 KKK17839.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Parvo_NS1 PF01057.12 KKK17839.1 - 0.091 11.6 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 KKK17839.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KKK17839.1 - 0.1 11.7 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 KKK17839.1 - 0.17 11.7 0.0 0.51 10.2 0.0 1.7 1 0 0 1 1 1 0 Torsin PIF1 PF05970.9 KKK17839.1 - 0.52 9.2 0.0 0.85 8.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Sec66 PF09802.4 KKK17840.1 - 3.5e-83 277.6 1.0 4.2e-83 277.4 0.7 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Sec2p PF06428.6 KKK17840.1 - 0.0096 15.7 3.5 0.0096 15.7 2.4 1.8 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p NIT PF08376.5 KKK17840.1 - 0.039 13.4 4.0 0.059 12.8 2.8 1.3 1 0 0 1 1 1 0 Nitrate and nitrite sensing Zip PF02535.17 KKK17841.1 - 3.5 6.5 7.7 7 5.5 5.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Glyoxalase_2 PF12681.2 KKK17842.1 - 3.1e-13 50.2 0.0 1e-12 48.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KKK17842.1 - 1.7e-10 40.9 0.0 9.2e-10 38.5 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KKK17842.1 - 0.00041 20.3 0.0 0.00079 19.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BCDHK_Adom3 PF10436.4 KKK17843.1 - 3.8e-42 143.6 0.0 5.4e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KKK17843.1 - 6.1e-18 64.5 0.0 2e-17 62.8 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.11 KKK17843.1 - 0.00048 20.6 0.3 0.0016 18.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 HATPase_c_2 PF13581.1 KKK17843.1 - 0.027 14.2 0.1 0.24 11.1 0.0 2.3 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 KKK17843.1 - 0.035 13.7 0.0 0.18 11.4 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF663 PF04950.7 KKK17844.1 - 8.1e-94 313.9 0.0 8.1e-94 313.9 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KKK17844.1 - 2.1e-25 88.0 0.0 4.5e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KKK17844.1 - 9.7e-07 28.4 0.0 0.00017 21.0 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KKK17844.1 - 1.3e-05 25.3 0.0 3.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK17844.1 - 8.8e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KKK17844.1 - 0.00042 20.2 0.0 0.0013 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK17844.1 - 0.00053 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KKK17844.1 - 0.00059 19.5 0.3 0.0015 18.2 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KKK17844.1 - 0.0014 18.5 0.0 0.0038 17.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KKK17844.1 - 0.0025 18.6 0.0 0.0025 18.6 0.0 4.6 3 1 1 4 4 3 1 AAA domain Miro PF08477.8 KKK17844.1 - 0.0029 18.0 0.0 0.0088 16.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_19 PF13245.1 KKK17844.1 - 0.0031 17.2 0.2 0.0077 15.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KKK17844.1 - 0.0039 16.8 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KKK17844.1 - 0.0045 17.2 1.1 0.014 15.6 0.0 2.4 3 0 0 3 3 1 1 ABC transporter AAA_25 PF13481.1 KKK17844.1 - 0.0077 15.6 0.0 0.025 13.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KKK17844.1 - 0.011 15.4 0.3 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 KKK17844.1 - 0.013 14.4 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 KKK17844.1 - 0.013 15.1 0.1 0.031 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KKK17844.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KKK17844.1 - 0.013 15.1 0.2 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 KKK17844.1 - 0.014 14.8 0.2 0.026 13.9 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KKK17844.1 - 0.016 15.3 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.4 KKK17844.1 - 0.017 14.6 0.0 0.14 11.6 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KKK17844.1 - 0.028 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 KKK17844.1 - 0.065 12.2 1.1 0.29 10.1 0.0 2.2 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.12 KKK17844.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 KKK17844.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Aminotran_1_2 PF00155.16 KKK17845.1 - 9.2e-23 80.7 0.0 1.2e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK17845.1 - 0.004 16.3 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KKK17845.1 - 0.071 12.1 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Tfb4 PF03850.9 KKK17846.1 - 3.7e-117 390.4 0.0 4.3e-117 390.2 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 CAP_N PF01213.14 KKK17846.1 - 0.41 9.8 3.2 0.71 9.0 2.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GDPD PF03009.12 KKK17847.1 - 8.4e-68 228.6 0.0 9.6e-67 225.1 0.0 2.4 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KKK17847.1 - 5.3e-29 100.3 0.3 1.4e-12 47.7 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.14 KKK17847.1 - 2.6e-28 99.5 5.1 1.2e-14 54.7 0.4 3.4 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 KKK17847.1 - 1.4e-27 95.5 2.5 8.8e-10 38.8 0.0 5.1 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KKK17847.1 - 2.2e-23 80.8 5.8 0.00038 20.1 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 KKK17847.1 - 1.3e-19 69.7 1.6 2e-07 31.0 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK17847.1 - 4e-15 54.4 2.8 0.027 14.6 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat Actin PF00022.14 KKK17848.1 - 2.7e-89 299.3 0.0 6.2e-89 298.1 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KKK17848.1 - 0.042 12.4 0.0 0.91 8.0 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 KKK17849.1 - 2.3e-37 128.4 1.1 1.3e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Asparaginase IstB_IS21 PF01695.12 KKK17849.1 - 0.012 15.0 0.1 0.026 13.9 0.0 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF1940 PF09155.5 KKK17849.1 - 0.097 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Vps55 PF04133.9 KKK17852.1 - 1.2e-43 147.6 5.7 1.3e-43 147.5 3.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 TrbC PF04956.8 KKK17852.1 - 4.2 7.4 9.6 0.69 9.9 0.7 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF1049 PF06305.6 KKK17852.1 - 5.1 6.6 12.3 3.9 7.0 2.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Proteasome PF00227.21 KKK17853.1 - 2.7e-49 167.0 0.1 3.4e-49 166.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KKK17853.1 - 2.8e-12 45.7 0.3 4.4e-12 45.0 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature UPF0220 PF05255.6 KKK17854.1 - 6.7e-47 158.8 1.0 7.3e-47 158.7 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) G3P_antiterm PF04309.7 KKK17854.1 - 0.082 11.9 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Lysine_decarbox PF03641.9 KKK17855.1 - 4.9e-26 91.1 0.0 1.3e-25 89.7 0.0 1.7 1 1 0 1 1 1 1 Possible lysine decarboxylase DUF3684 PF12449.3 KKK17856.1 - 0 1512.3 0.0 0 1511.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3684) Chorismate_bind PF00425.13 KKK17856.1 - 7.7e-63 212.2 0.0 8.7e-62 208.7 0.0 2.2 1 1 0 1 1 1 1 chorismate binding enzyme Med6 PF04934.9 KKK17856.1 - 6.1e-41 139.2 0.0 1.9e-40 137.6 0.0 1.9 2 0 0 2 2 2 1 MED6 mediator sub complex component GATase PF00117.23 KKK17856.1 - 3e-26 92.0 0.0 2e-25 89.3 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KKK17856.1 - 6.8e-10 39.1 0.0 2.5e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region HATPase_c_3 PF13589.1 KKK17856.1 - 0.00028 20.5 0.0 0.00079 19.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C26 PF07722.8 KKK17856.1 - 0.00035 20.0 0.1 0.00091 18.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 WLM PF08325.5 KKK17856.1 - 8.7 6.1 7.6 0.48 10.2 0.0 2.6 3 0 0 3 3 3 0 WLM domain WW PF00397.21 KKK17861.1 - 3.3e-07 30.0 2.6 3.3e-07 30.0 1.8 2.7 3 0 0 3 3 3 1 WW domain AIPR PF10592.4 KKK17861.1 - 0.049 12.9 2.0 0.069 12.4 1.4 1.2 1 0 0 1 1 1 0 AIPR protein Spore_coat_CotO PF14153.1 KKK17861.1 - 2.4 7.5 14.1 0.35 10.2 3.3 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Mcp5_PH PF12814.2 KKK17866.1 - 3.5e-43 146.4 0.3 7.1e-43 145.4 0.2 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology WHIM2 PF15613.1 KKK17866.1 - 0.071 13.0 0.3 12 6.0 0.5 2.7 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 2 DUF846 PF05832.7 KKK17866.1 - 1.2 8.8 0.1 1.9 8.1 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) BAR PF03114.13 KKK17867.1 - 2.7e-08 33.5 1.8 3.2e-08 33.3 1.2 1.2 1 0 0 1 1 1 1 BAR domain DUF4541 PF15074.1 KKK17867.1 - 0.08 13.4 3.8 0.18 12.3 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) Apolipoprotein PF01442.13 KKK17867.1 - 0.097 12.1 2.1 0.41 10.1 1.4 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2439 PF10382.4 KKK17868.1 - 8e-29 99.6 0.4 1.3e-28 99.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Utp14 PF04615.8 KKK17881.1 - 0.8 7.7 19.3 0.89 7.6 13.3 1.1 1 0 0 1 1 1 0 Utp14 protein FAM196 PF15265.1 KKK17881.1 - 3.2 6.8 31.9 3.9 6.5 22.1 1.1 1 0 0 1 1 1 0 FAM196 family NPP1 PF05630.6 KKK17891.1 - 9.3e-58 195.3 0.0 1.1e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) p450 PF00067.17 KKK17893.1 - 5.7e-42 143.7 0.0 1.1e-41 142.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.10 KKK17894.1 - 9.8e-28 96.8 31.2 1.3e-27 96.4 21.6 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3938 PF13074.1 KKK17894.1 - 0.68 9.8 6.4 1.2 9.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Methyltransf_11 PF08241.7 KKK17897.1 - 5.7e-07 29.9 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK17897.1 - 0.00056 19.6 0.0 0.0019 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain SH3BGR PF04908.10 KKK17899.1 - 0.0026 17.6 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Pneumo_att_G PF05539.6 KKK17899.1 - 7.8 5.7 10.3 11 5.2 7.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ribul_P_3_epim PF00834.14 KKK17900.1 - 1.1e-63 213.9 0.0 1.5e-62 210.3 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Amidohydro_2 PF04909.9 KKK17900.1 - 0.00084 18.9 0.4 0.0052 16.3 0.1 2.2 1 1 1 2 2 2 1 Amidohydrolase QRPTase_C PF01729.14 KKK17900.1 - 0.0044 16.5 0.1 0.87 9.0 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.9 KKK17900.1 - 0.024 13.7 0.1 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.19 KKK17900.1 - 0.047 13.0 0.2 0.068 12.5 0.1 1.6 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Rad50_zn_hook PF04423.9 KKK17901.1 - 0.0091 15.4 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 Rad50 zinc hook motif LSM PF01423.17 KKK17902.1 - 5.3e-14 51.5 1.0 8.1e-14 50.9 0.7 1.3 1 0 0 1 1 1 1 LSM domain Cellulase PF00150.13 KKK17903.1 - 1.5e-17 63.7 0.4 3.2e-17 62.6 0.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TFIIS_C PF01096.13 KKK17905.1 - 2.3 7.9 5.2 0.25 10.9 0.3 1.9 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PHO4 PF01384.15 KKK17906.1 - 9.9e-101 336.6 19.4 1.2e-100 336.3 13.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.11 KKK17907.1 - 1.5e-23 83.0 29.2 1.5e-23 83.0 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu-oxidase_3 PF07732.10 KKK17908.1 - 2.3e-39 133.7 4.8 4.6e-39 132.7 0.5 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KKK17908.1 - 1.3e-32 112.8 0.0 1.1e-31 109.8 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK17908.1 - 8.7e-15 54.4 10.7 4.9e-14 52.0 0.3 3.0 2 1 0 2 2 2 2 Multicopper oxidase PAZ PF02170.17 KKK17908.1 - 0.14 11.4 0.0 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 PAZ domain Abhydrolase_6 PF12697.2 KKK17909.1 - 3.8e-11 43.3 0.2 9.2e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 KKK17909.1 - 6.5e-11 41.4 0.0 8.8e-11 41.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 KKK17909.1 - 1.7e-10 40.7 0.0 4.3e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK17909.1 - 2e-06 27.1 0.0 4.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KKK17909.1 - 0.00038 19.9 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KKK17909.1 - 0.00078 19.2 0.0 0.0034 17.1 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1771 PF08590.5 KKK17909.1 - 0.01 15.8 0.7 0.024 14.6 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) DLH PF01738.13 KKK17909.1 - 0.019 14.2 0.0 0.21 10.8 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 KKK17909.1 - 0.026 14.0 0.3 0.5 9.8 0.0 2.9 2 2 1 3 3 3 0 alpha/beta hydrolase fold Esterase PF00756.15 KKK17909.1 - 0.046 13.1 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Abhydrolase_3 PF07859.8 KKK17909.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 KKK17909.1 - 0.076 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase MmgE_PrpD PF03972.9 KKK17909.1 - 0.11 10.6 0.0 0.17 10.0 0.0 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Glyco_hydro_75 PF07335.6 KKK17910.1 - 8.2e-49 165.4 0.1 1.1e-48 165.1 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 UDPG_MGDP_dh_N PF03721.9 KKK17911.1 - 8.6e-36 123.0 0.0 3.6e-24 85.1 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KKK17911.1 - 8.2e-13 48.4 0.0 6.2e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 KKK17911.1 - 2.1e-09 37.4 0.0 2.5e-08 34.0 0.0 2.5 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Ldh_1_N PF00056.18 KKK17911.1 - 0.1 12.4 0.1 17 5.2 0.0 3.2 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain AA_permease PF00324.16 KKK17912.1 - 1.6e-110 369.6 39.9 2e-110 369.4 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK17912.1 - 2.1e-35 122.0 45.6 2.6e-35 121.8 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease CBM-like PF14683.1 KKK17913.1 - 5e-40 136.8 0.0 1.1e-39 135.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KKK17913.1 - 1.4e-24 86.0 0.7 1.4e-24 86.0 0.5 2.5 4 0 0 4 4 4 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KKK17913.1 - 5.1e-10 39.2 2.3 1.7e-08 34.3 0.3 2.9 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 KKK17913.1 - 0.0037 17.2 0.2 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4198) Ald_Xan_dh_C2 PF02738.13 KKK17914.1 - 1.1e-185 618.1 0.2 1.5e-185 617.7 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KKK17914.1 - 3.1e-41 140.6 0.0 5.3e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 KKK17914.1 - 5.8e-32 109.6 0.2 3.8e-31 107.0 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 KKK17914.1 - 3.3e-28 97.9 0.0 7.8e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 KKK17914.1 - 3.9e-25 87.5 0.0 1e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KKK17914.1 - 4.8e-08 32.6 0.1 2.7e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain AAA PF00004.24 KKK17915.1 - 3.4e-16 59.6 0.0 6.7e-06 26.3 0.0 3.4 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK17915.1 - 3.8e-13 49.7 0.2 0.0072 16.4 0.0 4.6 3 1 1 4 4 4 3 AAA domain AAA_17 PF13207.1 KKK17915.1 - 5.5e-12 46.5 0.0 0.05 14.4 0.0 4.1 3 1 0 3 3 3 3 AAA domain AAA_18 PF13238.1 KKK17915.1 - 2.7e-09 37.4 0.0 0.093 13.0 0.0 3.8 3 0 0 3 3 3 3 AAA domain AAA_19 PF13245.1 KKK17915.1 - 1.2e-07 31.4 0.1 0.0086 15.8 0.0 3.9 3 0 0 3 3 3 2 Part of AAA domain AAA_33 PF13671.1 KKK17915.1 - 1.8e-07 31.1 0.1 0.0091 15.8 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KKK17915.1 - 2.3e-07 30.9 0.2 0.72 9.8 0.0 3.7 3 1 0 3 3 3 3 AAA ATPase domain AAA_5 PF07728.9 KKK17915.1 - 4.9e-07 29.5 0.1 0.37 10.5 0.0 3.7 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Torsin PF06309.6 KKK17915.1 - 6.8e-07 29.2 0.0 0.045 13.6 0.0 3.6 3 0 0 3 3 3 1 Torsin Mg_chelatase PF01078.16 KKK17915.1 - 1.2e-05 24.5 0.0 0.23 10.5 0.0 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KKK17915.1 - 0.00018 21.5 2.5 3.3 7.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain RuvB_N PF05496.7 KKK17915.1 - 0.00019 20.5 0.0 0.56 9.2 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KKK17915.1 - 0.00035 20.6 0.1 1.8 8.7 0.0 3.9 5 1 0 5 5 3 1 RNA helicase Sigma54_activ_2 PF14532.1 KKK17915.1 - 0.00059 19.8 0.0 0.099 12.6 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_2 PF07724.9 KKK17915.1 - 0.0012 18.7 0.0 1 9.2 0.0 3.8 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 KKK17915.1 - 0.002 17.7 0.0 0.87 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KKK17915.1 - 0.0025 17.4 0.4 2.7 7.5 0.0 3.6 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KKK17915.1 - 0.0028 17.0 0.0 3.4 7.0 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein ABC_tran PF00005.22 KKK17915.1 - 0.0037 17.5 0.0 0.94 9.7 0.0 3.3 3 1 0 3 3 3 1 ABC transporter NACHT PF05729.7 KKK17915.1 - 0.0047 16.6 0.0 2.6 7.6 0.0 3.2 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 KKK17915.1 - 0.0087 15.5 0.0 7.7 5.9 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain PRK PF00485.13 KKK17915.1 - 0.009 15.5 1.0 3.9 6.9 0.1 3.6 4 0 0 4 4 4 1 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 KKK17915.1 - 0.018 14.5 0.0 13 5.4 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain MobB PF03205.9 KKK17915.1 - 0.019 14.6 0.0 14 5.4 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KKK17915.1 - 0.053 12.9 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain VirE PF05272.6 KKK17915.1 - 0.057 12.8 0.0 16 4.9 0.0 3.3 4 0 0 4 4 4 0 Virulence-associated protein E NTPase_1 PF03266.10 KKK17915.1 - 0.14 11.8 0.1 13 5.4 0.0 2.5 2 0 0 2 2 2 0 NTPase MIT PF04212.13 KKK17916.1 - 0.00027 20.7 0.2 0.00052 19.8 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 KKK17916.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat ADH_zinc_N PF00107.21 KKK17918.1 - 8e-19 67.4 0.2 1.3e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK17918.1 - 1e-06 28.4 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KKK17918.1 - 2.1e-06 28.6 0.0 5.8e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aminotran_5 PF00266.14 KKK17919.1 - 2.6e-15 56.0 0.0 3.5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KKK17919.1 - 3.5e-08 32.7 0.0 5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KKK17919.1 - 0.035 13.1 0.0 0.68 8.9 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family GYF PF02213.11 KKK17920.1 - 2.3e-18 65.5 0.1 5.2e-18 64.3 0.1 1.7 1 0 0 1 1 1 1 GYF domain PRO8NT PF08082.6 KKK17920.1 - 0.16 11.5 0.6 0.29 10.7 0.4 1.3 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Abi PF02517.11 KKK17922.1 - 1.1e-14 54.3 6.6 1.1e-14 54.3 4.6 2.7 3 1 0 3 3 3 1 CAAX protease self-immunity tRNA-synt_1 PF00133.17 KKK17923.1 - 1.9e-48 164.9 0.3 2.5e-39 134.8 0.0 4.9 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KKK17923.1 - 4e-41 140.3 0.0 5.7e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Suc_Fer-like PF06999.7 KKK17923.1 - 4.7e-34 118.3 0.0 7.8e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1g PF09334.6 KKK17923.1 - 3.6e-27 95.0 0.1 3.5e-24 85.2 0.0 3.0 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1d PF00750.14 KKK17923.1 - 0.0012 17.7 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) Anticodon_1 PF08264.8 KKK17924.1 - 1.4e-10 41.1 0.0 2.8e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.17 KKK17924.1 - 3.9e-06 25.1 0.0 8.1e-06 24.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KKK17924.1 - 0.031 12.9 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) 2-Hacid_dh_C PF02826.14 KKK17925.1 - 2.9e-50 169.8 0.0 5.5e-50 168.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK17925.1 - 1.5e-14 53.5 0.0 2.1e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KKK17925.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 KKK17925.1 - 0.11 13.0 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Drf_GBD PF06371.8 KKK17927.1 - 2.3e-72 242.3 0.5 5.5e-72 241.0 0.0 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KKK17927.1 - 1.4e-54 184.5 3.6 9.4e-54 181.8 0.0 2.6 2 1 1 3 3 3 2 Diaphanous FH3 Domain MBOAT PF03062.14 KKK17928.1 - 2e-41 142.1 5.3 3.8e-41 141.2 3.7 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF679 PF05078.7 KKK17928.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF679) DUF4149 PF13664.1 KKK17928.1 - 4.5 7.3 8.5 0.28 11.2 0.2 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) Sec1 PF00995.18 KKK17929.1 - 1.1e-150 502.9 0.0 1.3e-150 502.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.14 KKK17929.1 - 0.016 15.1 0.4 0.052 13.4 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain Nop14 PF04147.7 KKK17930.1 - 7.1e-286 950.5 30.0 8.3e-286 950.3 20.8 1.0 1 0 0 1 1 1 1 Nop14-like family PPR_2 PF13041.1 KKK17931.1 - 1e-07 31.7 0.2 0.097 12.6 0.0 4.9 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.1 KKK17931.1 - 9.5e-05 22.3 0.0 17 6.0 0.0 6.2 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 KKK17931.1 - 0.024 14.5 2.0 7.5 6.7 0.0 4.6 5 0 0 5 5 5 0 PPR repeat HEAT_2 PF13646.1 KKK17932.1 - 0.033 14.4 0.1 0.075 13.3 0.1 1.7 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.17 KKK17932.1 - 0.036 14.1 0.1 0.65 10.2 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat CDC45 PF02724.9 KKK17932.1 - 0.074 11.0 0.3 0.096 10.7 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein ORC3_N PF07034.6 KKK17933.1 - 1.6e-15 56.8 0.1 1e-09 37.8 0.0 3.2 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus CTD_bind PF04818.8 KKK17934.1 - 0.00017 21.7 0.2 0.001 19.2 0.0 2.2 2 2 0 2 2 2 1 RNA polymerase II-binding domain. MULE PF10551.4 KKK17934.1 - 0.0024 18.0 0.0 1.3 9.2 0.0 2.1 2 0 0 2 2 2 2 MULE transposase domain VHS PF00790.14 KKK17934.1 - 0.0024 17.5 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 VHS domain Inhibitor_I9 PF05922.11 KKK17935.1 - 0.0026 18.3 0.0 0.0028 18.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 HOOK PF05622.7 KKK17936.1 - 9.5e-24 83.2 23.2 9.5e-24 83.2 16.1 2.5 2 0 0 2 2 2 2 HOOK protein DUF4164 PF13747.1 KKK17936.1 - 0.0097 16.0 1.9 0.0097 16.0 1.3 6.5 4 3 2 6 6 6 1 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.4 KKK17936.1 - 0.039 13.7 71.0 0.12 12.1 3.5 6.4 4 1 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KIP1 PF07765.7 KKK17936.1 - 4.5 7.1 8.6 2.7 7.9 0.1 4.6 4 1 2 6 6 6 0 KIP1-like protein EB1 PF03271.12 KKK17937.1 - 2.5e-17 62.6 1.1 4.5e-17 61.8 0.8 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KKK17937.1 - 2.9e-06 27.2 1.4 6.8e-06 26.0 0.6 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain Cullin PF00888.17 KKK17941.1 - 1.7e-46 158.9 0.0 6.6e-46 157.0 0.0 1.9 2 0 0 2 2 2 1 Cullin family Pkr1 PF08636.5 KKK17941.1 - 6.8e-34 115.7 5.7 1.6e-33 114.5 4.0 1.7 1 0 0 1 1 1 1 ER protein Pkr1 APC2 PF08672.6 KKK17941.1 - 4e-23 81.4 0.0 9.9e-23 80.1 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Calreticulin PF00262.13 KKK17941.1 - 0.076 11.6 0.2 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Calreticulin family Mito_fiss_reg PF05308.6 KKK17941.1 - 1.2 8.3 7.8 3.1 7.1 5.4 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA_12 PF13087.1 KKK17942.1 - 7.6e-41 139.6 0.0 1.5e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK17942.1 - 1.1e-28 100.4 0.3 4.4e-28 98.4 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK17942.1 - 1.2e-07 31.3 0.0 1.2e-06 28.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KKK17942.1 - 2.1e-06 27.4 0.2 0.0036 16.8 0.1 2.8 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KKK17942.1 - 7.1e-05 21.9 0.1 0.15 11.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KKK17942.1 - 0.00034 20.4 0.0 0.00085 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KKK17942.1 - 0.0013 18.3 0.3 0.79 9.2 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KKK17942.1 - 0.0044 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MxiH PF09392.5 KKK17942.1 - 0.13 12.8 0.5 0.46 11.0 0.3 1.9 1 0 0 1 1 1 0 Type III secretion needle MxiH like Pkinase PF00069.20 KKK17943.1 - 1.1e-68 231.2 0.0 1.9e-68 230.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17943.1 - 8.3e-42 143.0 0.0 1.2e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK17943.1 - 9.1e-11 41.2 0.0 3.6e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KKK17943.1 - 0.041 12.9 0.3 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK17943.1 - 0.073 12.7 4.8 1.8 8.2 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Peptidase_C15 PF01470.12 KKK17945.1 - 5.2e-13 49.3 0.0 0.00018 21.3 0.0 3.1 2 1 0 2 2 2 2 Pyroglutamyl peptidase GATA PF00320.22 KKK17947.1 - 4e-16 58.0 2.4 7.2e-16 57.2 1.7 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 KKK17947.1 - 0.024 13.9 0.2 0.045 13.0 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding YscO PF07321.7 KKK17947.1 - 0.035 13.9 4.9 0.051 13.4 3.4 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO GAS PF13851.1 KKK17947.1 - 0.046 12.9 1.0 0.07 12.3 0.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 KKK17947.1 - 0.071 13.1 3.8 0.24 11.4 2.6 1.7 1 1 0 1 1 1 0 DivIVA protein ArfGap PF01412.13 KKK17947.1 - 0.077 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.12 KKK17947.1 - 0.18 11.4 0.2 0.32 10.6 0.2 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 CENP-F_leu_zip PF10473.4 KKK17947.1 - 0.22 11.3 5.2 11 5.9 0.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.7 KKK17947.1 - 0.57 10.1 5.8 2.2 8.3 1.0 3.2 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat WD40_alt PF14077.1 KKK17947.1 - 1.7 8.3 4.4 24 4.6 0.0 3.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif Med21 PF11221.3 KKK17948.1 - 4e-59 198.7 0.0 5.2e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 KKK17948.1 - 0.0024 17.5 4.8 0.012 15.3 0.3 2.5 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Spore_III_AB PF09548.5 KKK17948.1 - 0.011 15.5 0.5 0.017 14.9 0.1 1.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF4455 PF14643.1 KKK17948.1 - 0.093 11.3 0.3 0.12 10.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) CENP-Q PF13094.1 KKK17948.1 - 0.17 11.9 1.8 0.28 11.2 1.2 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ALIX_LYPXL_bnd PF13949.1 KKK17948.1 - 0.17 10.8 1.8 0.25 10.2 1.3 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Spc24 PF08286.6 KKK17949.1 - 7e-38 128.9 0.4 8.5e-37 125.4 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 KKK17949.1 - 0.059 13.3 0.4 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Prefoldin_2 PF01920.15 KKK17949.1 - 0.63 9.8 6.5 2 8.1 0.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit APG6 PF04111.7 KKK17949.1 - 0.64 9.0 6.0 0.88 8.5 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Viral_P18 PF04521.8 KKK17949.1 - 1.8 8.0 6.1 0.55 9.6 0.7 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein HR1 PF02185.11 KKK17949.1 - 1.9 8.2 7.3 1.5 8.6 0.5 2.2 2 0 0 2 2 2 0 Hr1 repeat DMPK_coil PF08826.5 KKK17949.1 - 3.2 7.7 10.9 1.1 9.1 1.1 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like PI3_PI4_kinase PF00454.22 KKK17950.1 - 7.1e-34 117.3 0.0 1.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.18 KKK17951.1 - 7e-58 195.7 0.2 1e-57 195.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK17951.1 - 6.7e-11 41.9 0.1 4.4e-08 32.8 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KKK17951.1 - 8.3e-06 25.4 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 KKK17951.1 - 0.0023 17.5 1.1 0.004 16.8 0.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KKK17951.1 - 0.071 12.9 1.3 0.14 11.9 0.9 1.5 1 0 0 1 1 1 0 Ring finger domain HIRAN PF08797.6 KKK17951.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 HIRAN domain Fis1_TPR_C PF14853.1 KKK17952.1 - 1.7e-24 85.4 0.5 2.7e-24 84.7 0.3 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KKK17952.1 - 1.9e-17 62.2 0.0 3.2e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.1 KKK17952.1 - 0.00046 20.7 0.2 0.0008 20.0 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK17952.1 - 0.0058 16.4 1.1 0.0058 16.4 0.8 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF357 PF04010.8 KKK17952.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF357) TPR_11 PF13414.1 KKK17952.1 - 0.14 11.8 0.5 0.18 11.4 0.4 1.4 1 1 0 1 1 1 0 TPR repeat zf-RING_2 PF13639.1 KKK17953.1 - 3.7e-15 55.4 8.7 3.7e-15 55.4 6.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK17953.1 - 1.4e-10 40.6 10.4 4e-09 36.0 3.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK17953.1 - 2.4e-08 33.9 4.6 2.4e-08 33.9 3.2 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KKK17953.1 - 3.1e-08 33.5 8.2 3.1e-08 33.5 5.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK17953.1 - 2.5e-06 27.0 7.8 2.5e-06 27.0 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK17953.1 - 1.1e-05 25.0 13.0 1.5e-05 24.5 4.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_3 PF14369.1 KKK17953.1 - 0.00028 20.8 6.4 0.0085 16.0 2.0 2.7 2 0 0 2 2 2 1 zinc-finger zf-Apc11 PF12861.2 KKK17953.1 - 0.00082 19.1 3.3 0.00082 19.1 2.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 KKK17953.1 - 0.0016 18.1 5.7 0.0032 17.1 0.2 2.2 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Baculo_RING PF05883.6 KKK17953.1 - 0.048 13.5 0.9 0.048 13.5 0.6 1.8 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 KKK17953.1 - 0.35 10.4 12.7 0.069 12.7 2.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 KKK17953.1 - 0.49 10.2 7.6 2.4 8.0 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 KKK17953.1 - 0.63 9.7 14.2 0.11 12.1 5.0 2.4 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.3 KKK17953.1 - 1.4 8.8 9.5 1 9.3 4.2 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KKK17953.1 - 1.6 8.5 5.6 3.7 7.3 3.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 KKK17953.1 - 2.2 8.0 11.5 11 5.7 3.7 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 UPF0547 PF10571.4 KKK17953.1 - 2.3 8.0 9.9 3.8 7.2 0.2 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 KKK17953.1 - 4.8 7.0 7.5 7.2 6.4 0.1 3.0 2 1 1 3 3 3 0 zinc-ribbons zf-ribbon_3 PF13248.1 KKK17953.1 - 6.1 6.1 6.5 30 3.9 0.0 3.0 2 1 1 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KKK17953.1 - 9.3 5.9 9.9 50 3.5 0.2 4.1 3 1 0 4 4 4 0 zinc-ribbon domain PQ-loop PF04193.9 KKK17954.1 - 1.6e-30 104.3 6.6 5.8e-18 64.1 0.9 2.4 2 0 0 2 2 2 2 PQ loop repeat APH PF01636.18 KKK17955.1 - 2.4e-15 56.9 0.4 7.8e-15 55.2 0.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KKK17955.1 - 0.0038 16.2 0.0 0.0084 15.1 0.0 1.5 1 0 0 1 1 1 1 Fructosamine kinase Dicty_REP PF05086.7 KKK17957.1 - 0.052 11.3 0.9 0.061 11.0 0.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein IBN_N PF03810.14 KKK17961.1 - 0.00014 21.7 0.1 0.00058 19.7 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Peptidase_M24 PF00557.19 KKK17962.1 - 2.2e-42 145.0 0.0 3.2e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KKK17962.1 - 3.7e-22 79.2 0.0 4.9e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Sec8_exocyst PF04048.9 KKK17963.1 - 1.5e-52 177.0 3.1 4.8e-52 175.3 2.2 2.0 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KKK17963.1 - 8.9e-10 37.9 1.0 1.8e-09 36.9 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 KKK17963.1 - 3.5e-05 22.1 0.9 7.2e-05 21.1 0.6 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.1 KKK17963.1 - 6e-05 22.8 1.1 0.00012 21.8 0.8 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.7 KKK17963.1 - 0.012 14.1 6.3 0.016 13.6 3.3 1.9 2 0 0 2 2 2 0 Dor1-like family DUF3829 PF12889.2 KKK17963.1 - 0.057 12.6 0.1 0.057 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF812 PF05667.6 KKK17963.1 - 0.071 11.6 3.7 0.023 13.2 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DPBB_1 PF03330.13 KKK17964.1 - 2e-11 43.7 3.2 2.5e-11 43.4 0.0 2.8 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 KKK17964.1 - 0.00063 19.4 0.4 0.0017 18.1 0.3 1.6 1 0 0 1 1 1 1 Pollen allergen HLH PF00010.21 KKK17965.1 - 2.5e-13 49.5 1.9 5.9e-13 48.2 1.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SAC3_GANP PF03399.11 KKK17966.1 - 3.5e-54 183.4 0.0 4.9e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family CN_hydrolase PF00795.17 KKK17966.1 - 3e-10 39.7 0.0 8.4e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PCI_Csn8 PF10075.4 KKK17966.1 - 0.2 11.4 0.0 0.56 9.9 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 MUG113 PF13455.1 KKK17967.1 - 9.6e-34 115.6 0.1 2e-33 114.6 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KKK17967.1 - 4.2e-24 84.8 0.0 1.1e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain PAT1 PF09770.4 KKK17967.1 - 1.9 6.6 15.2 2.3 6.3 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1649 PF07855.7 KKK17971.1 - 4.7e-64 214.9 0.0 5.5e-64 214.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Peroxin-3 PF04882.7 KKK17972.1 - 3.2e-145 484.1 0.0 3.7e-145 483.9 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 MFS_1 PF07690.11 KKK17973.1 - 2.9e-35 121.6 29.9 2.9e-35 121.6 20.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KKK17973.1 - 0.12 12.2 4.9 0.063 13.0 1.0 2.4 2 0 0 2 2 2 0 MFS_1 like family RNA_pol_I_A49 PF06870.7 KKK17974.1 - 2.2e-52 177.9 1.9 6.7e-39 133.5 1.5 2.7 2 1 0 2 2 2 2 A49-like RNA polymerase I associated factor NOT2_3_5 PF04153.13 KKK17980.1 - 2.1e-34 118.2 0.5 8.3e-34 116.3 0.0 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.8 KKK17981.1 - 1.1e-19 70.1 0.2 1.5e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 KKK17981.1 - 0.38 9.9 2.8 0.63 9.2 1.9 1.4 1 0 0 1 1 1 0 Clc-like SMC_N PF02463.14 KKK17982.1 - 2.1e-59 200.4 4.7 7.6e-59 198.5 3.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KKK17982.1 - 2.2e-23 82.4 1.4 3.4e-22 78.6 0.2 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KKK17982.1 - 6.8e-14 52.6 6.0 6.8e-14 52.6 4.2 6.4 2 2 3 5 5 2 1 AAA domain AAA_21 PF13304.1 KKK17982.1 - 1e-11 45.3 8.1 1.1e-05 25.5 0.0 3.7 3 0 0 3 3 3 2 AAA domain CUE PF02845.11 KKK17982.1 - 1.2e-11 43.8 0.0 4.4e-11 42.0 0.0 2.1 1 0 0 1 1 1 1 CUE domain AAA_29 PF13555.1 KKK17982.1 - 0.0001 21.7 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_DNA_bd PF12329.3 KKK17982.1 - 0.00079 19.1 9.4 0.00079 19.1 6.5 11.3 9 2 3 12 12 12 2 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 KKK17982.1 - 0.0016 17.0 27.8 0.0016 17.0 19.2 6.4 3 2 3 6 6 6 2 AAA domain Reo_sigmaC PF04582.7 KKK17982.1 - 0.0043 16.2 28.7 0.57 9.3 1.1 5.7 3 2 2 5 5 5 3 Reovirus sigma C capsid protein GAS PF13851.1 KKK17982.1 - 0.0052 15.9 12.2 0.0052 15.9 8.4 7.1 2 2 3 6 6 6 2 Growth-arrest specific micro-tubule binding DUF1796 PF08795.5 KKK17982.1 - 0.27 10.8 12.6 9.5 5.8 0.3 3.7 2 1 1 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) Tyr-DNA_phospho PF06087.7 KKK17983.1 - 2.5e-150 500.9 0.0 3.2e-150 500.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DIE2_ALG10 PF04922.7 KKK17983.1 - 1e-76 258.4 14.7 3.1e-70 237.1 5.7 2.4 2 1 0 2 2 2 2 DIE2/ALG10 family PLDc_2 PF13091.1 KKK17983.1 - 0.018 14.7 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain Sld5 PF05916.6 KKK17984.1 - 1.8e-31 108.5 0.0 2.6e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein U-box PF04564.10 KKK17985.1 - 4.1e-21 74.7 0.0 9e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KKK17985.1 - 5.4e-16 58.0 1.5 1.9e-13 49.8 0.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KKK17985.1 - 2e-07 30.3 5.7 0.00025 20.7 0.1 4.3 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK17985.1 - 2.3e-06 26.9 6.1 7.6e-05 22.1 0.1 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK17985.1 - 3.7e-06 27.4 7.4 0.0011 19.5 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK17985.1 - 2.2e-05 24.6 2.8 0.13 12.5 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK17985.1 - 6.2e-05 22.8 1.1 0.62 10.4 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK17985.1 - 6.8e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KKK17985.1 - 0.00019 21.2 3.1 0.038 13.9 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK17985.1 - 0.0072 16.8 7.1 0.77 10.5 0.0 3.8 3 2 1 4 4 4 1 Tetratricopeptide repeat GlnD_UR_UTase PF08335.6 KKK17985.1 - 0.016 15.0 2.6 0.025 14.4 1.8 1.3 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase GvpG PF05120.7 KKK17985.1 - 0.017 14.8 0.3 0.051 13.3 0.2 1.8 1 0 0 1 1 1 0 Gas vesicle protein G TPR_7 PF13176.1 KKK17985.1 - 0.81 9.6 6.1 8.2 6.4 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat ACBP PF00887.14 KKK17986.1 - 1.4e-20 72.6 0.7 2.1e-20 72.1 0.5 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Methyltransf_25 PF13649.1 KKK17987.1 - 8e-07 29.3 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK17987.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK17987.1 - 2.7e-05 23.3 0.0 4.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KKK17987.1 - 0.00091 19.6 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK17987.1 - 0.0021 18.0 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK17987.1 - 0.0036 17.7 0.0 0.0058 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KKK17987.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RseA_C PF03873.8 KKK17987.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Methyltransf_18 PF12847.2 KKK17987.1 - 0.1 13.2 0.0 0.21 12.1 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain ORC4_C PF14629.1 KKK17988.1 - 6.9e-57 192.1 0.0 1.1e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KKK17988.1 - 1.2e-16 61.2 0.2 5.7e-16 59.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KKK17988.1 - 2.7e-06 26.4 0.1 5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 KKK17988.1 - 9.4e-06 25.8 0.0 2.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK17988.1 - 0.00016 21.8 0.1 0.00069 19.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KKK17988.1 - 0.00037 19.5 0.0 0.00072 18.6 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 KKK17988.1 - 0.00056 19.6 1.5 0.0035 17.0 0.3 2.7 2 1 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 KKK17988.1 - 0.002 17.6 0.1 0.0061 16.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KKK17988.1 - 0.0029 17.3 0.0 0.01 15.5 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase ThiS-like PF14453.1 KKK17988.1 - 0.0081 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 ThiS-like ubiquitin PIF1 PF05970.9 KKK17988.1 - 0.17 10.8 0.1 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Zn_clus PF00172.13 KKK17989.1 - 1.5e-11 44.0 10.9 2.7e-11 43.1 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK17989.1 - 1.6e-10 40.1 0.2 2.5e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain 4HBT PF03061.17 KKK17990.1 - 1.1e-10 41.4 0.1 1.6e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily GDI PF00996.13 KKK17991.1 - 3.3e-183 608.9 0.0 4.2e-183 608.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KKK17991.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Vma12 PF11712.3 KKK17992.1 - 1.1e-40 138.5 0.0 1.5e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TSC21 PF15217.1 KKK17992.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 TSC21 family PsbN PF02468.10 KKK17992.1 - 0.71 9.5 3.7 0.4 10.3 0.2 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) CHCH PF06747.8 KKK17995.1 - 2.9e-08 33.3 4.8 5.3e-08 32.5 3.3 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 KKK17995.1 - 0.0029 17.7 1.2 0.0061 16.6 0.8 1.5 1 0 0 1 1 1 1 GCK domain ABC_tran PF00005.22 KKK17996.1 - 3.6e-47 160.0 0.4 2.6e-24 86.0 0.0 4.3 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KKK17996.1 - 2.9e-17 63.5 0.1 0.0019 18.2 0.1 4.3 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 KKK17996.1 - 1e-15 57.6 0.0 7.3e-06 25.3 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KKK17996.1 - 7.7e-10 39.4 0.9 0.00037 20.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KKK17996.1 - 4.3e-09 35.7 0.1 0.002 17.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KKK17996.1 - 9.4e-08 32.8 0.1 0.0061 17.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 KKK17996.1 - 1.4e-07 31.5 0.1 0.016 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK17996.1 - 6.5e-07 29.5 0.0 0.0058 16.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KKK17996.1 - 7.4e-07 28.4 0.0 0.00068 18.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KKK17996.1 - 1.5e-06 27.7 0.0 0.073 12.5 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KKK17996.1 - 7.1e-06 26.2 0.0 0.13 12.4 0.0 4.2 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK17996.1 - 8.9e-06 25.8 0.0 0.41 10.6 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 KKK17996.1 - 1.1e-05 25.3 0.0 0.017 15.0 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KKK17996.1 - 1.3e-05 24.7 0.0 0.3 10.4 0.0 3.1 4 0 0 4 4 3 2 AAA-like domain AAA_18 PF13238.1 KKK17996.1 - 1.5e-05 25.2 0.3 0.19 12.0 0.0 3.4 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 KKK17996.1 - 2.3e-05 24.1 0.0 0.059 13.2 0.0 2.8 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit HEAT_2 PF13646.1 KKK17996.1 - 2.7e-05 24.3 0.5 0.027 14.7 0.0 3.0 2 1 1 3 3 2 2 HEAT repeats Miro PF08477.8 KKK17996.1 - 3.7e-05 24.2 0.0 0.028 14.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_13 PF13166.1 KKK17996.1 - 5.7e-05 21.8 0.0 0.24 9.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 KKK17996.1 - 5.9e-05 22.7 0.0 0.064 12.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KKK17996.1 - 7.3e-05 22.6 0.0 0.27 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KKK17996.1 - 9.5e-05 22.5 0.0 0.54 10.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 KKK17996.1 - 0.0001 22.0 0.4 0.83 9.3 0.0 3.3 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 KKK17996.1 - 0.00013 21.1 1.9 0.47 9.4 0.0 4.0 3 2 2 5 5 5 1 AAA ATPase domain AAA_14 PF13173.1 KKK17996.1 - 0.00014 21.8 0.0 0.33 10.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 KKK17996.1 - 0.00016 21.4 0.0 0.13 11.9 0.0 3.0 2 0 0 2 2 2 1 Archaeal ATPase HEAT PF02985.17 KKK17996.1 - 0.00025 20.8 1.4 15 5.9 0.1 5.0 5 0 0 5 5 4 0 HEAT repeat Dynamin_N PF00350.18 KKK17996.1 - 0.00025 20.9 0.5 0.0029 17.4 0.0 2.6 3 0 0 3 3 2 1 Dynamin family cobW PF02492.14 KKK17996.1 - 0.0006 19.3 0.3 0.41 10.0 0.0 3.2 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KKK17996.1 - 0.00078 18.3 0.1 0.5 9.0 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_30 PF13604.1 KKK17996.1 - 0.0013 18.3 0.0 1.7 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KKK17996.1 - 0.0014 18.3 0.0 3.9 7.3 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain DUF87 PF01935.12 KKK17996.1 - 0.0018 18.1 3.8 0.13 12.0 0.0 3.3 4 0 0 4 4 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 KKK17996.1 - 0.002 17.5 0.0 2.5 7.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 KKK17996.1 - 0.0038 16.7 0.0 0.72 9.3 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 KKK17996.1 - 0.0059 16.1 0.1 3.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 KKK17996.1 - 0.0062 15.4 0.1 2.6 6.8 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_5 PF07728.9 KKK17996.1 - 0.012 15.2 0.0 11 5.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KKK17996.1 - 0.016 14.3 0.1 2.5 7.2 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Septin PF00735.13 KKK17996.1 - 0.017 14.1 0.1 1.5 7.7 0.0 2.7 3 0 0 3 3 2 0 Septin UPF0079 PF02367.12 KKK17996.1 - 0.027 14.1 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 KKK17996.1 - 0.029 13.2 0.3 0.27 10.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 KKK17996.1 - 0.035 13.5 0.2 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.1 KKK17996.1 - 0.061 12.8 0.1 11 5.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain GTP_EFTU PF00009.22 KKK17996.1 - 0.086 12.2 0.1 6.4 6.1 0.0 2.8 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain HEAT_EZ PF13513.1 KKK17996.1 - 2.1 8.9 8.8 1e+02 3.5 0.0 5.2 4 2 1 5 5 4 0 HEAT-like repeat MIF4G PF02854.14 KKK17998.1 - 2.3e-59 200.3 0.1 2.6e-31 108.6 0.0 3.7 4 0 0 4 4 4 2 MIF4G domain Upf2 PF04050.9 KKK17998.1 - 3.1e-55 186.5 17.5 3.1e-55 186.5 12.1 2.1 2 0 0 2 2 2 1 Up-frameshift suppressor 2 ETF PF01012.16 KKK17999.1 - 1e-40 139.1 2.9 1e-40 139.1 2.0 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KKK17999.1 - 4.2e-34 116.0 0.1 8.3e-34 115.0 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SUN PF03856.8 KKK18000.1 - 2.8e-99 331.4 14.3 5e-99 330.6 9.9 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Fer4_10 PF13237.1 KKK18000.1 - 0.083 12.7 0.7 0.19 11.5 0.2 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Macoilin PF09726.4 KKK18000.1 - 3.4 5.8 5.5 4.6 5.4 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L1 PF00687.16 KKK18001.1 - 6.9e-58 195.5 4.6 6.9e-58 195.5 3.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family EF-hand_1 PF00036.27 KKK18002.1 - 1.3e-12 46.0 2.7 5e-06 25.4 0.5 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KKK18002.1 - 1.9e-12 45.9 2.8 6.9e-06 25.5 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KKK18002.1 - 2.3e-11 43.6 3.0 3e-09 36.8 0.2 2.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KKK18002.1 - 1.3e-08 33.8 6.2 0.0009 18.4 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KKK18002.1 - 1.5e-06 27.7 0.3 0.042 13.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 KKK18002.1 - 0.045 13.6 0.0 13 5.7 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain RabGAP-TBC PF00566.13 KKK18003.1 - 3.6e-17 62.5 0.0 7.8e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RRM_1 PF00076.17 KKK18004.1 - 1.5e-18 66.2 0.0 2.7e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK18004.1 - 3.1e-15 55.9 0.0 3.8e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18004.1 - 0.00056 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) X8 PF07983.8 KKK18007.1 - 1.4e-25 89.5 5.3 3.2e-25 88.4 3.7 1.6 1 0 0 1 1 1 1 X8 domain Pox_A12 PF04651.8 KKK18007.1 - 0.079 13.0 1.3 0.14 12.2 0.9 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein RVP_2 PF08284.6 KKK18008.1 - 0.039 13.8 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Sugar_tr PF00083.19 KKK18020.1 - 2.8e-07 29.4 0.8 3.3e-07 29.2 0.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter V-SNARE_C PF12352.3 KKK18020.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus tRNA-synt_1 PF00133.17 KKK18054.1 - 2.1e-167 557.7 0.0 2.8e-167 557.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KKK18054.1 - 1e-22 80.5 1.0 1.9e-22 79.6 0.7 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KKK18054.1 - 4.6e-22 78.2 0.0 1.1e-12 47.3 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 KKK18054.1 - 0.00032 20.2 3.6 0.00054 19.5 1.8 2.0 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1d PF00750.14 KKK18054.1 - 0.018 13.8 0.0 0.094 11.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1_2 PF13603.1 KKK18054.1 - 0.043 13.1 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KKK18054.1 - 0.066 12.3 0.0 7.9 5.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain TF_Zn_Ribbon PF08271.7 KKK18054.1 - 0.13 11.5 1.0 0.25 10.6 0.7 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding UPF0183 PF03676.9 KKK18055.1 - 1.4e-35 122.6 0.0 1e-24 86.9 0.0 3.7 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 KKK18056.1 - 5.5e-112 373.7 1.9 1.6e-111 372.2 1.3 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 KKK18056.1 - 5.8e-09 36.2 3.4 5.8e-09 36.2 2.4 5.7 3 2 3 6 6 6 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.7 KKK18056.1 - 0.00021 21.1 31.8 0.00029 20.6 0.2 5.8 1 1 2 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.6 KKK18056.1 - 0.85 9.4 15.8 0.26 11.1 1.5 4.9 3 3 0 3 3 3 0 Protein of unknown function (DUF1515) ABC_tran PF00005.22 KKK18058.1 - 4.4e-47 159.8 0.0 5.8e-30 104.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK18058.1 - 1.4e-33 116.4 30.3 3.6e-18 65.9 10.7 3.7 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KKK18058.1 - 4.4e-12 45.7 0.2 0.0012 18.1 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KKK18058.1 - 7.9e-06 25.3 0.0 0.17 11.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KKK18058.1 - 1.7e-05 25.2 1.7 0.0064 16.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KKK18058.1 - 0.00013 21.0 0.0 0.12 11.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 KKK18058.1 - 0.00014 22.0 0.0 1.7 8.8 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK18058.1 - 0.00022 21.2 1.8 0.041 13.8 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KKK18058.1 - 0.00025 20.5 0.4 0.78 9.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KKK18058.1 - 0.0014 18.6 0.5 0.24 11.2 0.0 3.5 2 2 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KKK18058.1 - 0.0028 17.1 0.0 3.5 6.9 0.0 2.7 2 1 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 KKK18058.1 - 0.0035 18.1 0.0 0.85 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KKK18058.1 - 0.005 16.7 0.0 0.28 11.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KKK18058.1 - 0.0063 15.7 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 KKK18058.1 - 0.011 15.5 2.1 0.31 10.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2075 PF09848.4 KKK18058.1 - 0.022 13.7 0.0 1.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SbcCD_C PF13558.1 KKK18058.1 - 0.025 14.4 0.0 4.7 7.2 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 KKK18058.1 - 0.029 13.4 0.0 1.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 KKK18058.1 - 0.036 14.5 0.0 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein IstB_IS21 PF01695.12 KKK18058.1 - 0.043 13.2 0.0 0.37 10.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.17 KKK18058.1 - 0.11 11.3 0.0 5.5 5.7 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.1 KKK18058.1 - 0.12 11.8 0.4 11 5.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.7 KKK18058.1 - 0.22 10.8 0.3 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AA_permease PF00324.16 KKK18060.1 - 1.4e-106 356.7 40.3 1.6e-106 356.5 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK18060.1 - 2.1e-28 99.0 42.9 2.8e-28 98.6 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease Trp_oprn_chp PF09534.5 KKK18060.1 - 0.26 10.8 9.6 0.28 10.7 0.1 2.8 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pox_P21 PF05313.7 KKK18060.1 - 9.9 5.3 8.2 2.8 7.1 2.9 2.0 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Bac_rhodopsin PF01036.13 KKK18061.1 - 2.4e-33 115.3 15.3 3e-33 115.0 10.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Mucin PF01456.12 KKK18061.1 - 0.16 11.7 11.1 0.29 10.8 7.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-Apc11 PF12861.2 KKK18062.1 - 6.4e-47 157.3 10.6 7.2e-47 157.1 7.4 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KKK18062.1 - 4e-32 110.1 8.9 4.7e-32 109.9 6.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KKK18062.1 - 6.3e-08 32.3 18.4 4.4e-07 29.6 12.6 2.5 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK18062.1 - 1.4e-05 24.6 11.9 0.0009 18.8 8.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK18062.1 - 0.00028 20.8 14.8 0.0033 17.4 10.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KKK18062.1 - 0.00048 19.6 11.8 0.022 14.3 6.2 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KKK18062.1 - 0.00094 19.0 2.0 0.00094 19.0 1.4 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KKK18062.1 - 0.00099 18.7 15.3 0.0077 15.9 10.8 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK18062.1 - 0.001 18.6 13.8 0.0038 16.8 9.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KKK18062.1 - 0.0014 18.5 15.6 0.032 14.1 10.8 3.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-HIT PF04438.11 KKK18062.1 - 0.017 14.7 3.5 0.05 13.2 0.4 2.4 2 0 0 2 2 2 0 HIT zinc finger zf-RING_3 PF14369.1 KKK18062.1 - 0.057 13.4 2.7 8.1 6.5 0.1 3.2 3 0 0 3 3 3 0 zinc-finger zf-RING_UBOX PF13445.1 KKK18062.1 - 0.13 11.9 7.2 0.23 11.1 3.1 2.4 1 1 1 2 2 2 0 RING-type zinc-finger DUF2256 PF10013.4 KKK18062.1 - 0.13 11.9 0.4 0.13 11.9 0.3 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.7 KKK18062.1 - 0.14 11.8 4.1 0.92 9.2 0.1 2.3 2 0 0 2 2 2 0 DBF zinc finger zf-RING-like PF08746.6 KKK18062.1 - 0.23 11.5 11.9 1.4 9.0 8.2 2.2 1 1 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 KKK18062.1 - 0.35 10.4 6.0 0.76 9.3 4.2 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 KKK18062.1 - 0.4 10.4 13.4 1.7 8.4 9.3 2.0 1 1 0 1 1 1 0 PHD-finger DUF329 PF03884.9 KKK18062.1 - 0.48 10.0 0.1 0.48 10.0 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF329) RecR PF02132.10 KKK18062.1 - 0.79 9.2 4.2 5.5 6.5 0.1 3.0 3 0 0 3 3 3 0 RecR protein Opy2 PF09463.5 KKK18062.1 - 1 9.4 8.9 2.2 8.4 3.4 2.2 2 0 0 2 2 2 0 Opy2 protein DZR PF12773.2 KKK18062.1 - 1.2 8.9 11.1 29 4.5 7.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon RINGv PF12906.2 KKK18062.1 - 8.8 6.4 14.4 18 5.5 9.1 2.2 1 1 1 2 2 2 0 RING-variant domain Rhodanese PF00581.15 KKK18063.1 - 1.2e-18 67.4 0.0 1.6e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain RPEL PF02755.10 KKK18064.1 - 3.3e-19 67.5 10.0 6e-11 41.3 1.3 2.5 2 0 0 2 2 2 2 RPEL repeat PBP_sp32 PF07222.7 KKK18064.1 - 0.019 14.1 6.0 0.018 14.2 4.2 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RNA_pol_3_Rpc31 PF11705.3 KKK18064.1 - 0.27 11.1 8.0 0.29 11.0 5.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 V_ATPase_I PF01496.14 KKK18064.1 - 4.7 4.9 6.4 5.3 4.7 4.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIN_4 PF13638.1 KKK18065.1 - 0.0015 18.6 0.1 0.054 13.5 0.1 2.5 2 1 0 2 2 2 2 PIN domain Glyco_hydro_2_N PF02837.13 KKK18066.1 - 2.1e-12 46.9 0.0 1.1e-11 44.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KKK18066.1 - 1.5e-11 44.7 0.1 4.4e-11 43.2 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KKK18066.1 - 3.6e-05 22.8 0.1 6.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Translin PF01997.11 KKK18067.1 - 3.9e-72 242.0 0.0 4.6e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Translin family IMS PF00817.15 KKK18068.1 - 3.2e-41 140.5 1.6 5.5e-41 139.8 0.4 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KKK18068.1 - 1e-15 57.7 2.4 2.8e-15 56.3 0.1 2.7 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KKK18068.1 - 1.7e-05 24.5 0.0 4.7e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif VPS28 PF03997.7 KKK18068.1 - 0.053 13.1 0.2 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 VPS28 protein FHA PF00498.21 KKK18069.1 - 4.3e-08 33.1 0.2 1.1e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KKK18069.1 - 0.00064 19.8 0.0 0.16 12.1 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Exonuc_VII_L PF02601.10 KKK18069.1 - 1.2 8.3 13.9 3.8 6.5 9.6 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit GFA PF04828.9 KKK18070.1 - 3.7e-20 71.6 0.2 5e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Spc7_N PF15402.1 KKK18071.1 - 0.01 13.8 6.2 0.013 13.5 4.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 F-box-like PF12937.2 KKK18073.1 - 0.0043 16.7 0.0 0.015 15.0 0.0 2.0 1 1 0 1 1 1 1 F-box-like Mannosyl_trans PF05007.8 KKK18074.1 - 1.3e-72 244.6 8.9 1.7e-57 195.0 6.9 2.4 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) Fungal_trans PF04082.13 KKK18074.1 - 2.9e-24 85.3 0.7 5.3e-24 84.5 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PIG-U PF06728.8 KKK18074.1 - 2.8e-11 42.9 0.6 2.8e-11 42.9 0.4 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KKK18074.1 - 9.5e-07 28.5 6.5 9.5e-07 28.5 4.5 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2029) Zn_clus PF00172.13 KKK18074.1 - 1.3e-05 25.0 12.9 2.2e-05 24.2 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 KKK18076.1 - 3.4e-169 563.0 2.9 3.2e-158 526.8 0.5 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Allantoicase PF03561.10 KKK18077.1 - 4.2e-86 286.0 0.0 1.7e-45 154.1 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.21 KKK18078.1 - 4.6e-30 103.6 0.0 1.6e-29 101.8 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK18078.1 - 1.3e-22 79.9 0.9 4.1e-21 75.0 0.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KKK18078.1 - 2.7e-20 72.1 0.0 9.2e-20 70.4 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KKK18078.1 - 1.1e-12 48.2 0.6 2.3e-11 43.9 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain GAF_2 PF13185.1 KKK18078.1 - 6.8e-12 46.1 0.2 2.4e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.20 KKK18078.1 - 5.6e-08 32.2 0.0 5.5e-07 28.9 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 KKK18078.1 - 1.8e-07 31.3 0.2 2.1e-06 27.8 0.0 2.9 3 0 0 3 3 3 1 GAF domain GAF PF01590.21 KKK18078.1 - 1.9e-07 31.3 0.0 3.3e-06 27.3 0.0 2.7 2 0 0 2 2 2 1 GAF domain TPR_12 PF13424.1 KKK18078.1 - 3e-06 27.0 3.7 0.062 13.2 0.0 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK18078.1 - 7e-05 22.3 0.0 0.07 12.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 KKK18078.1 - 0.001 19.2 0.1 2 8.5 0.0 3.6 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 KKK18078.1 - 0.0013 17.6 0.0 1.3 7.7 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain TPR_11 PF13414.1 KKK18078.1 - 0.0024 17.4 2.1 2.1 8.0 0.0 5.2 5 1 1 6 6 6 1 TPR repeat TPR_2 PF07719.12 KKK18078.1 - 0.016 15.1 0.0 52 4.1 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HATPase_c_3 PF13589.1 KKK18078.1 - 0.018 14.7 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_1 PF00515.23 KKK18078.1 - 0.039 13.5 0.0 21 4.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NACHT PF05729.7 KKK18078.1 - 0.067 12.8 0.0 0.78 9.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 KKK18078.1 - 0.14 11.3 0.0 0.39 9.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TPR_14 PF13428.1 KKK18078.1 - 0.2 12.3 7.3 7.1 7.5 0.0 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Cytochrome_CBB3 PF13442.1 KKK18079.1 - 0.038 14.1 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DNA_pol_A PF00476.15 KKK18079.1 - 0.039 12.5 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family A Sugar_tr PF00083.19 KKK18080.1 - 5.2e-16 58.2 10.5 6.2e-16 58.0 7.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK18080.1 - 0.00022 20.0 10.8 0.00029 19.6 7.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily E1-E2_ATPase PF00122.15 KKK18090.1 - 2.7e-21 75.6 0.2 9.5e-21 73.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KKK18090.1 - 1e-16 62.0 0.0 3.8e-15 56.8 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK18090.1 - 1.4e-14 54.7 0.1 9.9e-14 51.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK18090.1 - 1.3e-10 41.1 0.0 4.5e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK18090.1 - 0.00066 19.3 0.3 0.0035 16.9 0.1 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase AMP-binding PF00501.23 KKK18091.1 - 5.5e-79 265.5 0.0 8.1e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK18091.1 - 0.00011 23.0 0.1 0.00032 21.5 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PBP_like PF12727.2 KKK18091.1 - 0.14 11.0 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain Thioredoxin PF00085.15 KKK18093.1 - 8.5e-30 102.5 0.2 9.6e-30 102.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KKK18093.1 - 5.2e-08 33.0 0.7 5.4e-07 29.8 0.5 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KKK18093.1 - 2.7e-07 30.6 0.0 5.6e-05 23.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 KKK18093.1 - 1.2e-05 24.8 0.3 0.0025 17.3 0.2 2.0 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 KKK18093.1 - 4.9e-05 22.8 0.0 6.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KKK18093.1 - 0.0015 18.1 0.1 0.0031 17.1 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_4 PF13462.1 KKK18093.1 - 0.037 14.0 0.3 0.15 12.0 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.1 KKK18093.1 - 0.066 12.6 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 KKK18093.1 - 0.073 13.0 0.2 0.1 12.6 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.19 KKK18093.1 - 0.16 12.0 0.3 0.29 11.1 0.2 1.6 1 1 0 1 1 1 0 Glutaredoxin Asp-B-Hydro_N PF05279.6 KKK18094.1 - 1.1 9.0 5.8 2.4 7.9 4.0 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Es2 PF09751.4 KKK18095.1 - 2.7e-101 340.0 0.0 7.5e-101 338.5 0.0 1.6 1 1 0 1 1 1 1 Nuclear protein Es2 Mid1 PF12929.2 KKK18096.1 - 9.9e-128 426.4 17.3 6.4e-126 420.5 12.0 2.0 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Ras PF00071.17 KKK18103.1 - 1.3e-39 135.1 0.0 1.4e-38 131.8 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK18103.1 - 4.8e-17 62.5 0.0 7.8e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK18103.1 - 4.5e-11 42.2 0.0 7.2e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK18103.1 - 0.0015 17.7 0.0 0.002 17.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK18103.1 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KKK18103.1 - 0.0021 18.1 0.0 0.005 16.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KKK18103.1 - 0.0032 17.4 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 KKK18103.1 - 0.0076 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KKK18103.1 - 0.0089 15.5 0.0 0.082 12.3 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KKK18103.1 - 0.031 13.8 0.2 6 6.3 0.1 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KKK18103.1 - 0.038 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KKK18103.1 - 0.054 13.4 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KKK18103.1 - 0.07 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KKK18103.1 - 0.084 12.4 0.1 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KKK18103.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 KKK18103.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KKK18103.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 KKK18103.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KKK18103.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF3431 PF11913.3 KKK18104.1 - 2.4e-91 305.1 1.1 2.9e-91 304.9 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Sec63 PF02889.11 KKK18105.1 - 1.7e-151 503.8 0.0 2.3e-96 322.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KKK18105.1 - 1.9e-53 180.3 1.2 1.5e-27 96.1 0.6 4.0 5 0 0 5 5 5 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK18105.1 - 1.4e-17 63.3 0.0 2.2e-07 30.6 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KKK18105.1 - 2.3e-16 60.1 0.0 7.1e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KKK18105.1 - 8.3e-08 32.4 0.1 0.0051 16.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KKK18105.1 - 3e-05 23.6 0.2 0.027 14.1 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain SNF2_N PF00176.18 KKK18105.1 - 9.7e-05 21.3 0.2 0.22 10.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 KKK18105.1 - 0.0072 15.8 0.1 0.9 8.9 0.1 3.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KKK18105.1 - 0.014 14.5 0.2 10 5.1 0.0 3.7 4 0 0 4 4 4 0 Zeta toxin IstB_IS21 PF01695.12 KKK18105.1 - 0.02 14.3 0.7 7.6 5.9 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_10 PF12846.2 KKK18105.1 - 0.041 13.3 0.0 10 5.4 0.0 3.5 3 1 0 4 4 4 0 AAA-like domain Nucleo_P87 PF07267.6 KKK18106.1 - 0.8 8.3 6.5 1.2 7.7 4.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MARVEL PF01284.18 KKK18107.1 - 4.4e-19 68.7 12.8 5.3e-19 68.4 8.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2615 PF11027.3 KKK18107.1 - 0.0037 17.1 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) DUF872 PF05915.7 KKK18107.1 - 0.12 12.1 0.2 9.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) CTP_transf_1 PF01148.15 KKK18107.1 - 0.19 11.3 6.7 0.24 11.0 4.7 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family ATP-synt_8 PF00895.15 KKK18107.1 - 1.1 9.4 3.8 3.3 7.9 0.1 3.0 3 0 0 3 3 3 0 ATP synthase protein 8 DUF2427 PF10348.4 KKK18107.1 - 4.5 6.8 7.9 3.7 7.1 3.3 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF2427) YL1_C PF08265.6 KKK18108.1 - 6.1e-16 57.6 0.2 1e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Profilin PF00235.14 KKK18109.1 - 3.3e-34 117.5 0.1 4.9e-34 117.0 0.1 1.2 1 0 0 1 1 1 1 Profilin SNAP PF14938.1 KKK18109.1 - 0.064 12.3 2.9 0.094 11.8 2.0 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Actin PF00022.14 KKK18110.1 - 1.1e-52 178.8 0.0 3.2e-29 101.5 0.0 2.2 2 0 0 2 2 2 2 Actin Phage_connect_1 PF05135.8 KKK18110.1 - 0.062 13.4 0.4 0.18 12.0 0.3 1.8 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein DASH_Dad4 PF08650.5 KKK18111.1 - 5.3e-27 93.5 6.7 6.8e-27 93.1 4.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 KKK18111.1 - 0.01 15.4 2.7 0.014 15.0 1.9 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 Kdo PF06293.9 KKK18111.1 - 0.051 12.6 0.1 0.059 12.4 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GM_CSF PF01109.12 KKK18111.1 - 0.059 13.3 0.4 0.076 12.9 0.2 1.2 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor MitMem_reg PF13012.1 KKK18111.1 - 0.064 13.3 3.1 0.095 12.7 2.1 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function PhyH PF05721.8 KKK18112.1 - 2.9e-08 33.9 0.0 1.5e-06 28.3 0.0 2.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Het-C PF07217.6 KKK18113.1 - 2.2e-295 980.7 0.0 2.2e-295 980.7 0.0 1.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C TctA PF01970.11 KKK18113.1 - 0.015 13.7 0.0 0.024 13.0 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family IBN_N PF03810.14 KKK18114.1 - 1.2e-11 44.3 0.1 4.9e-08 32.7 0.0 4.2 2 1 1 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KKK18114.1 - 1.8e-05 24.6 0.9 0.046 13.6 0.0 4.4 5 0 0 5 5 5 2 Exportin 1-like protein Cnd3 PF12719.2 KKK18114.1 - 0.0023 16.9 1.8 0.42 9.5 0.4 3.5 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CAS_CSE1 PF03378.10 KKK18114.1 - 0.0059 14.9 0.0 0.014 13.7 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Proteasom_PSMB PF10508.4 KKK18114.1 - 0.01 14.1 0.0 0.038 12.2 0.0 2.0 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit DUF1678 PF07913.6 KKK18114.1 - 0.066 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) RIX1 PF08167.7 KKK18114.1 - 0.099 12.3 3.3 1 8.9 0.1 3.8 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis DUF937 PF06078.6 KKK18114.1 - 0.21 11.8 3.9 39 4.4 0.0 4.0 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF937) Methyltransf_23 PF13489.1 KKK18115.1 - 8.9e-23 80.7 0.0 1.5e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18115.1 - 6.7e-11 42.7 0.0 3.4e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK18115.1 - 2.3e-10 40.8 0.0 6.1e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK18115.1 - 5.7e-10 38.9 0.0 2.7e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18115.1 - 2.8e-08 34.1 0.0 6.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK18115.1 - 0.00042 20.3 0.0 0.0017 18.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KKK18115.1 - 0.0021 17.1 0.0 0.007 15.4 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 KKK18115.1 - 0.0022 17.1 0.0 0.0058 15.7 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 KKK18115.1 - 0.003 17.0 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KKK18115.1 - 0.0054 16.1 0.0 0.044 13.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 KKK18115.1 - 0.0068 16.4 0.0 0.011 15.7 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 KKK18115.1 - 0.017 15.4 0.0 0.066 13.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KKK18115.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KKK18115.1 - 0.086 12.3 0.0 0.38 10.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF938) HORMA PF02301.13 KKK18116.1 - 8.4e-26 90.7 0.0 1.1e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Fungal_trans PF04082.13 KKK18117.1 - 9.7e-37 126.2 0.0 1.5e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MRI PF15325.1 KKK18117.1 - 3.7 8.5 5.3 39 5.2 0.0 2.7 2 0 0 2 2 2 0 Modulator of retrovirus infection Glyco_hydro_18 PF00704.23 KKK18118.1 - 4e-48 164.6 2.4 5.6e-48 164.1 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KKK18118.1 - 3.8e-10 39.4 0.0 9.7e-06 25.3 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KKK18118.1 - 0.002 18.0 3.6 0.002 18.0 2.5 3.8 3 0 0 3 3 3 1 Chitin recognition protein DUF92 PF01940.11 KKK18119.1 - 6.6e-58 195.5 11.9 8.9e-58 195.1 8.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Amidohydro_1 PF01979.15 KKK18120.1 - 2.8e-25 89.6 0.0 9.2e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KKK18120.1 - 7.5e-15 54.5 0.1 4e-14 52.1 0.1 2.2 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KKK18120.1 - 4.2e-09 36.1 0.1 2.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KKK18120.1 - 8.1e-09 35.9 0.2 0.00041 20.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Bcr-Abl_Oligo PF09036.5 KKK18120.1 - 0.17 11.8 0.6 0.69 9.9 0.1 2.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Methyltransf_33 PF10017.4 KKK18121.1 - 1.7e-26 92.5 0.3 3.1e-26 91.7 0.2 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KKK18121.1 - 5e-22 78.5 1.8 4.2e-20 72.2 1.2 2.3 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KKK18121.1 - 6e-09 36.3 0.1 8.9e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.1 KKK18121.1 - 0.00073 19.8 0.0 0.0084 16.4 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Xpo1 PF08389.7 KKK18123.1 - 1e-43 148.8 0.1 6e-43 146.2 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein MFS_1 PF07690.11 KKK18123.1 - 4.1e-36 124.4 62.3 4.9e-26 91.2 22.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HEAT PF02985.17 KKK18123.1 - 0.00031 20.5 0.1 0.91 9.7 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Tom22 PF04281.8 KKK18123.1 - 0.49 9.9 4.0 12 5.3 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 PAP2_3 PF14378.1 KKK18124.1 - 7.4e-49 165.8 10.2 1e-48 165.4 7.1 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 KKK18124.1 - 9.1e-05 22.1 10.6 0.0001 21.9 5.6 2.2 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KKK18124.1 - 0.12 12.6 7.4 0.048 13.9 1.4 2.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal FGGY_C PF02782.11 KKK18125.1 - 1.1e-30 106.6 0.0 1.6e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KKK18125.1 - 2.1e-07 30.4 0.0 3.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain HAD_2 PF13419.1 KKK18128.1 - 3.6e-10 40.3 0.0 4.7e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK18128.1 - 1.6e-08 34.1 0.0 2.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KKK18128.1 - 4.4e-06 27.2 0.0 5.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DBD_Tnp_Hermes PF10683.4 KKK18128.1 - 0.13 11.7 0.1 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 Hermes transposase DNA-binding domain Fungal_trans_2 PF11951.3 KKK18132.1 - 1e-63 215.2 0.0 1.2e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain YcbB PF08664.5 KKK18132.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 YcbB domain V-ATPase_C PF03223.10 KKK18134.1 - 4.9e-79 265.9 0.0 5.4e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C COXG PF06240.8 KKK18134.1 - 0.11 12.2 0.1 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) Tropomyosin_1 PF12718.2 KKK18137.1 - 9.8e-51 171.3 35.7 1.1e-50 171.1 24.8 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KKK18137.1 - 2.6e-10 39.8 33.5 4e-05 22.8 13.0 2.6 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.4 KKK18137.1 - 0.00033 20.6 11.4 0.00033 20.6 7.9 2.6 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Mod_r PF07200.8 KKK18137.1 - 0.00085 19.2 24.9 0.041 13.8 12.8 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein ERM PF00769.14 KKK18137.1 - 0.0022 17.6 36.1 0.0047 16.4 10.7 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Atg14 PF10186.4 KKK18137.1 - 0.0027 16.7 26.8 0.0093 14.9 12.9 2.1 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Cast PF10174.4 KKK18137.1 - 0.0027 15.8 29.3 0.003 15.6 20.3 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 KKK18137.1 - 0.004 16.7 32.2 3.8 7.0 22.3 2.3 1 1 0 1 1 1 0 IncA protein DUF4200 PF13863.1 KKK18137.1 - 0.008 16.1 34.0 0.012 15.5 10.6 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Myosin_tail_1 PF01576.14 KKK18137.1 - 0.0088 13.8 30.7 0.011 13.5 21.3 1.2 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 KKK18137.1 - 0.015 15.1 28.1 0.22 11.3 6.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF641 PF04859.7 KKK18137.1 - 0.023 14.4 4.8 0.023 14.4 3.4 3.0 1 1 1 2 2 1 0 Plant protein of unknown function (DUF641) KAR9 PF08580.5 KKK18137.1 - 0.029 12.6 0.7 0.029 12.6 0.5 2.0 1 1 1 2 2 2 0 Yeast cortical protein KAR9 TMF_DNA_bd PF12329.3 KKK18137.1 - 0.039 13.7 38.2 0.032 14.0 10.9 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KKK18137.1 - 0.043 13.0 3.9 0.54 9.3 0.2 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Syntaxin-6_N PF09177.6 KKK18137.1 - 0.054 13.8 18.1 10 6.5 6.4 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.6 KKK18137.1 - 0.055 12.1 26.4 0.024 13.3 9.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4618 PF15397.1 KKK18137.1 - 0.06 12.6 23.5 0.17 11.1 7.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.16 KKK18137.1 - 0.068 13.1 30.6 0.15 12.0 1.0 4.7 1 1 5 6 6 6 0 bZIP transcription factor ADIP PF11559.3 KKK18137.1 - 0.08 12.8 29.9 0.49 10.2 6.5 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding WXG100 PF06013.7 KKK18137.1 - 0.087 12.8 16.7 3 7.9 0.2 3.6 1 1 2 3 3 3 0 Proteins of 100 residues with WXG IFT46_B_C PF12317.3 KKK18137.1 - 0.09 12.1 8.0 0.023 14.0 3.1 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal TMF_TATA_bd PF12325.3 KKK18137.1 - 0.091 12.4 28.0 0.16 11.6 11.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF869 PF05911.6 KKK18137.1 - 0.11 10.7 24.8 0.11 10.7 8.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) APG6 PF04111.7 KKK18137.1 - 0.11 11.5 33.5 0.27 10.2 13.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Laminin_II PF06009.7 KKK18137.1 - 0.12 12.1 17.4 0.11 12.2 4.0 2.3 1 1 1 2 2 2 0 Laminin Domain II GAS PF13851.1 KKK18137.1 - 0.16 11.1 30.5 0.48 9.5 14.8 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 KKK18137.1 - 0.19 10.1 22.4 0.43 8.9 15.5 1.6 1 1 0 1 1 1 0 AAA domain Jnk-SapK_ap_N PF09744.4 KKK18137.1 - 0.2 11.6 27.1 0.36 10.8 11.6 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF972 PF06156.8 KKK18137.1 - 0.2 12.0 24.3 0.38 11.1 9.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF4559 PF15112.1 KKK18137.1 - 0.24 10.5 16.9 0.17 11.0 11.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) BLOC1_2 PF10046.4 KKK18137.1 - 0.25 11.4 20.6 1.4 9.0 0.4 3.6 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 KKK18137.1 - 0.26 9.3 24.4 1.2 7.2 9.1 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.7 KKK18137.1 - 0.38 10.5 34.0 0.34 10.6 6.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4600 PF15372.1 KKK18137.1 - 0.41 10.8 23.8 0.45 10.7 6.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) FlaC_arch PF05377.6 KKK18137.1 - 0.42 10.5 18.0 0.18 11.7 1.1 4.1 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Fmp27_WPPW PF10359.4 KKK18137.1 - 0.43 8.9 23.5 0.38 9.1 6.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Fib_alpha PF08702.5 KKK18137.1 - 0.46 10.6 16.2 2.1 8.4 4.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Striatin PF08232.7 KKK18137.1 - 0.6 10.4 26.7 3 8.1 1.0 2.2 1 1 1 2 2 2 0 Striatin family Seryl_tRNA_N PF02403.17 KKK18137.1 - 0.62 10.1 28.0 4.9 7.2 8.1 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.1 KKK18137.1 - 0.76 9.1 33.4 0.33 10.3 11.4 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CCDC155 PF14662.1 KKK18137.1 - 0.81 9.2 31.9 0.28 10.7 13.2 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF724 PF05266.9 KKK18137.1 - 0.86 9.1 26.8 0.47 10.0 7.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Surfac_D-trimer PF09006.6 KKK18137.1 - 1.1 9.0 6.0 32 4.3 0.0 4.0 5 0 0 5 5 3 0 Lung surfactant protein D coiled-coil trimerisation DUF812 PF05667.6 KKK18137.1 - 1.1 7.6 26.9 1.3 7.4 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FUSC PF04632.7 KKK18137.1 - 1.1 7.5 7.8 1.3 7.3 5.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIVA PF05103.8 KKK18137.1 - 1.3 9.1 29.4 8.3 6.4 9.8 3.2 1 1 1 3 3 3 0 DivIVA protein DUF904 PF06005.7 KKK18137.1 - 1.8 8.8 35.3 3.8 7.8 4.6 3.8 1 1 2 3 3 2 0 Protein of unknown function (DUF904) PspA_IM30 PF04012.7 KKK18137.1 - 2 7.7 31.0 4.3 6.6 5.6 3.1 1 1 2 3 3 3 0 PspA/IM30 family CENP-F_leu_zip PF10473.4 KKK18137.1 - 2 8.2 33.1 19 5.0 15.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 KKK18137.1 - 2.3 5.4 28.6 5.6 4.1 19.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF342 PF03961.8 KKK18137.1 - 2.6 6.3 25.2 0.42 8.9 5.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TMCO5 PF14992.1 KKK18137.1 - 2.7 7.0 27.1 2.7 7.0 11.9 2.1 1 1 1 2 2 2 0 TMCO5 family DUF3287 PF11690.3 KKK18137.1 - 3 7.9 10.0 39 4.3 6.4 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) DUF4201 PF13870.1 KKK18137.1 - 3.1 7.1 27.3 97 2.3 18.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF2730 PF10805.3 KKK18137.1 - 3.3 7.4 17.5 1.8 8.3 3.3 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) MbeD_MobD PF04899.7 KKK18137.1 - 3.4 7.6 14.0 1.1 9.2 1.6 3.3 1 1 2 4 4 4 0 MbeD/MobD like DUF745 PF05335.8 KKK18137.1 - 3.4 7.1 19.9 4 6.9 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) SlyX PF04102.7 KKK18137.1 - 3.8 7.9 22.8 4.7 7.6 3.3 3.9 1 1 3 4 4 4 0 SlyX Nup54 PF13874.1 KKK18137.1 - 3.9 7.1 23.0 3.3 7.3 3.7 3.4 1 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF3450 PF11932.3 KKK18137.1 - 4.4 6.5 25.8 5.2 6.2 2.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.10 KKK18137.1 - 4.9 6.7 30.7 0.058 12.8 2.4 4.4 1 1 3 4 4 4 0 Septum formation initiator BRE1 PF08647.6 KKK18137.1 - 6.4 6.8 28.4 9.7 6.2 3.9 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase EHN PF06441.7 KKK18137.1 - 6.5 6.7 11.5 2 8.3 3.3 2.3 1 1 1 2 2 2 0 Epoxide hydrolase N terminus Phage_GP20 PF06810.6 KKK18137.1 - 8.9 5.7 27.4 3.2 7.1 11.3 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 V_ATPase_I PF01496.14 KKK18137.1 - 9.1 3.9 21.7 26 2.5 5.4 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fungal_trans_2 PF11951.3 KKK18138.1 - 2.5e-26 92.1 0.0 6.8e-26 90.7 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK18138.1 - 1.3e-07 31.3 8.2 1.3e-07 31.3 5.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.15 KKK18139.1 - 2.7e-172 573.1 1.1 3.2e-172 572.9 0.8 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KKK18139.1 - 2.8e-07 30.5 0.0 6.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KKK18139.1 - 0.00026 20.9 0.0 0.00058 19.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain CMAS PF02353.15 KKK18140.1 - 1.1e-62 211.6 0.1 1.4e-62 211.2 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KKK18140.1 - 4.1e-11 42.8 0.0 9.1e-11 41.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18140.1 - 8.3e-07 29.4 0.0 1.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK18140.1 - 0.00018 21.5 0.0 0.00049 20.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK18140.1 - 0.00095 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18140.1 - 0.0011 19.5 0.0 0.003 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK18140.1 - 0.0018 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KKK18140.1 - 0.006 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK18140.1 - 0.0081 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KKK18140.1 - 0.0091 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 N6_N4_Mtase PF01555.13 KKK18140.1 - 0.054 12.9 0.0 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 DNA methylase PCMT PF01135.14 KKK18140.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mucin PF01456.12 KKK18141.1 - 8e-06 25.6 27.2 8e-06 25.6 18.8 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein Dicty_REP PF05086.7 KKK18141.1 - 0.0089 13.8 4.6 0.011 13.5 3.2 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein SpoIIIAH PF12685.2 KKK18141.1 - 0.19 11.2 7.6 0.41 10.1 5.2 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Mito_fiss_reg PF05308.6 KKK18141.1 - 1 8.6 10.2 0.021 14.2 1.3 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator TrbC PF04956.8 KKK18141.1 - 2.9 7.9 8.7 0.2 11.7 1.1 2.4 2 1 1 3 3 3 0 TrbC/VIRB2 family DUF4366 PF14283.1 KKK18141.1 - 5 6.4 6.8 7.8 5.8 3.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) ATP-synt_S1 PF05827.7 KKK18142.1 - 1.8e-67 227.6 0.4 2.1e-67 227.3 0.3 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nuc_recep-AF1 PF11825.3 KKK18142.1 - 0.078 12.8 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 Nop25 PF09805.4 KKK18143.1 - 4.4e-36 123.9 17.8 4.4e-36 123.9 12.4 2.9 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) DUF4522 PF15022.1 KKK18143.1 - 0.0081 15.8 2.6 0.0081 15.8 1.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4522) MBOAT PF03062.14 KKK18144.1 - 3.8e-26 91.9 12.1 6.7e-26 91.1 8.4 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KKK18144.1 - 0.34 11.0 5.9 0.23 11.5 2.4 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family Tmemb_170 PF10190.4 KKK18145.1 - 4.4e-05 23.4 5.3 5.6e-05 23.1 3.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 ABC2_membrane_4 PF12730.2 KKK18145.1 - 0.93 8.6 9.1 4.1 6.4 6.3 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.27 KKK18146.1 - 1e-49 164.6 32.1 1.7e-09 37.1 2.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KKK18146.1 - 0.00044 20.0 0.4 0.11 12.2 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A OMPdecase PF00215.19 KKK18147.1 - 2.3e-77 259.3 0.0 3.4e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.13 KKK18147.1 - 1.2e-23 83.1 0.3 2.1e-23 82.3 0.2 1.4 1 0 0 1 1 1 1 MAPEG family ICMT PF04140.9 KKK18148.1 - 3.5e-05 23.9 1.5 3.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family AIG2 PF06094.7 KKK18150.1 - 1.2e-08 35.3 0.0 1.6e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family DUF1039 PF06287.6 KKK18150.1 - 0.049 13.5 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) PEX11 PF05648.9 KKK18151.1 - 2.6e-09 36.6 0.2 1.3e-07 31.0 0.1 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) DUF2269 PF10027.4 KKK18151.1 - 0.11 12.2 2.6 0.11 12.2 0.5 1.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Cullin_binding PF03556.10 KKK18152.1 - 4.6e-31 107.3 2.1 6.9e-31 106.8 0.1 1.9 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 KKK18152.1 - 9.6e-13 47.4 0.9 1.8e-12 46.5 0.3 1.8 2 0 0 2 2 2 1 UBA-like domain TAP_C PF03943.8 KKK18152.1 - 0.025 13.9 0.1 0.058 12.8 0.0 1.6 1 0 0 1 1 1 0 TAP C-terminal domain NOC3p PF07540.6 KKK18153.1 - 2.3e-35 120.7 0.3 2.3e-35 120.7 0.2 2.2 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 KKK18153.1 - 4.1e-33 114.1 0.0 4.1e-33 114.1 0.0 2.4 3 0 0 3 3 3 1 CBF/Mak21 family DUF2570 PF10828.3 KKK18153.1 - 0.41 10.2 2.5 1.1 8.8 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Dscam_C PF12355.3 KKK18154.1 - 6.3 7.0 7.0 17 5.7 1.8 2.5 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Mpv17_PMP22 PF04117.7 KKK18155.1 - 7.5e-14 51.1 0.8 1.1e-11 44.2 0.4 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family CDC48_N PF02359.13 KKK18157.1 - 7.6e-20 70.6 0.8 1.2e-19 70.0 0.3 1.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain UFD1 PF03152.9 KKK18157.1 - 0.07 12.2 0.0 2.2 7.3 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 eIF-1a PF01176.14 KKK18157.1 - 0.072 12.5 0.6 1.9 7.9 0.1 2.3 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 2-Hacid_dh_C PF02826.14 KKK18184.1 - 1.5e-20 73.0 0.0 1.9e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.13 KKK18185.1 - 1.3e-08 34.6 8.6 1.9e-08 34.0 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2478 PF10649.4 KKK18185.1 - 0.23 10.7 0.0 0.42 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) PUA PF01472.15 KKK18186.1 - 3.2e-15 55.6 0.1 4.4e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 PUA domain Methyltransf_6 PF03737.10 KKK18186.1 - 0.053 13.3 0.1 0.071 12.9 0.1 1.1 1 0 0 1 1 1 0 Demethylmenaquinone methyltransferase Mito_carr PF00153.22 KKK18187.1 - 4.9e-60 199.2 5.4 7.4e-21 73.6 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein TPK_catalytic PF04263.11 KKK18189.1 - 2.2e-20 72.4 0.0 7.8e-20 70.6 0.0 1.7 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KKK18189.1 - 2.8e-11 42.9 0.1 4.9e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Septin PF00735.13 KKK18190.1 - 5.2e-124 412.8 0.1 5.2e-124 412.8 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KKK18190.1 - 2.2e-07 30.8 0.0 4.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KKK18190.1 - 6.5e-05 22.1 0.3 0.00041 19.5 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KKK18190.1 - 0.00013 22.2 2.5 0.019 15.2 0.0 2.9 2 1 0 3 3 3 1 ABC transporter GTP_EFTU PF00009.22 KKK18190.1 - 0.00028 20.3 1.7 0.0033 16.8 0.0 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KKK18190.1 - 0.00092 18.3 1.6 0.0022 17.1 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 KKK18190.1 - 0.001 19.0 0.1 0.014 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 KKK18190.1 - 0.0028 17.4 3.7 0.57 9.9 0.0 3.5 4 0 0 4 4 4 1 Dynamin family AAA_10 PF12846.2 KKK18190.1 - 0.0033 16.9 4.1 0.0096 15.3 2.5 2.0 1 1 0 1 1 1 1 AAA-like domain Ras PF00071.17 KKK18190.1 - 0.0041 16.5 0.1 0.028 13.8 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.1 KKK18190.1 - 0.005 16.9 0.1 0.025 14.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK18190.1 - 0.0058 16.1 0.1 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 KKK18190.1 - 0.0074 16.7 0.6 0.026 14.9 0.0 2.2 3 0 0 3 3 2 1 Miro-like protein AAA_29 PF13555.1 KKK18190.1 - 0.0078 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KKK18190.1 - 0.031 13.8 0.4 4 6.9 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KKK18190.1 - 0.055 13.6 0.8 0.7 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 KKK18190.1 - 0.083 12.4 0.3 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KKK18190.1 - 0.092 12.4 0.1 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_32 PF13654.1 KKK18190.1 - 0.21 10.1 10.2 0.48 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain YlqD PF11068.3 KKK18190.1 - 0.22 11.5 9.4 0.46 10.5 6.5 1.5 1 0 0 1 1 1 0 YlqD protein V_ATPase_I PF01496.14 KKK18190.1 - 0.38 8.5 7.7 5.5 4.7 7.0 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.6 KKK18190.1 - 1.3 8.2 6.7 2.3 7.4 4.7 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.10 KKK18190.1 - 4.8 6.2 12.0 4 6.5 7.2 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 KKK18190.1 - 5.6 6.5 9.8 9.3 5.7 6.8 1.3 1 0 0 1 1 1 0 IncA protein UPF0121 PF03661.8 KKK18191.1 - 1.6e-08 34.0 0.2 1.6e-08 34.0 0.2 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0121) An_peroxidase PF03098.10 KKK18193.1 - 4.3e-94 315.7 0.0 7e-92 308.5 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase DUF2235 PF09994.4 KKK18194.1 - 3.9e-114 380.7 0.4 5.1e-114 380.3 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Amino_oxidase PF01593.19 KKK18196.1 - 2.4e-43 148.8 0.4 2.1e-27 96.3 0.1 2.5 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KKK18196.1 - 7.5e-14 51.5 0.6 1.6e-13 50.4 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK18196.1 - 2.3e-07 31.0 0.3 1.3e-05 25.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK18196.1 - 7.9e-07 28.9 0.4 0.0041 16.9 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 KKK18196.1 - 1e-06 29.0 0.1 1.9e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK18196.1 - 2.6e-05 22.8 1.2 2.9e-05 22.7 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KKK18196.1 - 4e-05 23.6 1.2 0.00034 20.5 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK18196.1 - 0.00011 21.3 0.5 0.00018 20.5 0.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK18196.1 - 0.00031 19.7 1.0 0.00045 19.1 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK18196.1 - 0.00043 19.4 0.1 0.00078 18.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KKK18196.1 - 0.0016 17.5 0.1 0.0024 16.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KKK18196.1 - 0.0037 16.1 0.5 0.0058 15.5 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KKK18196.1 - 0.012 15.1 0.2 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KKK18196.1 - 0.022 14.4 1.3 0.031 13.9 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KKK18196.1 - 0.046 12.7 0.8 0.072 12.1 0.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 KKK18196.1 - 0.047 13.7 0.4 0.079 12.9 0.3 1.3 1 0 0 1 1 1 0 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 KKK18196.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 KKK18196.1 - 0.13 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FMO-like PF00743.14 KKK18196.1 - 0.17 10.0 0.0 0.29 9.2 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like WAP PF00095.16 KKK18197.1 - 0.0049 16.8 34.7 0.46 10.4 2.4 4.4 3 1 1 4 4 4 4 WAP-type (Whey Acidic Protein) 'four-disulfide core' Nodulin_late PF07127.6 KKK18197.1 - 0.013 15.5 1.7 0.013 15.5 1.2 5.0 5 0 0 5 5 5 0 Late nodulin protein Dickkopf_N PF04706.7 KKK18197.1 - 0.042 14.0 34.6 0.42 10.8 1.6 4.9 4 1 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region Toxin_23 PF08093.6 KKK18197.1 - 0.047 13.6 28.5 0.1 12.5 0.8 4.2 4 1 0 4 4 4 0 Magi 5 toxic peptide family TPT PF03151.11 KKK18198.1 - 1.8e-13 50.4 12.3 1.8e-13 50.4 8.5 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KKK18198.1 - 3.2e-05 23.9 9.6 3.2e-05 23.9 6.7 2.7 2 2 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 KKK18198.1 - 0.00037 19.5 16.0 0.0009 18.2 11.1 1.6 1 1 0 1 1 1 1 UAA transporter family Aldedh PF00171.17 KKK18199.1 - 1.6e-139 465.2 0.1 8.7e-82 274.8 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 KKK18199.1 - 0.037 12.7 0.1 0.059 12.0 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1266 PF06889.6 KKK18199.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Alpha-amylase PF00128.19 KKK18200.1 - 1e-94 317.4 1.5 1.7e-94 316.7 1.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KKK18200.1 - 0.0021 17.0 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Glyco_transf_25 PF01755.12 KKK18201.1 - 0.00096 18.8 0.0 0.65 9.6 0.0 2.6 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Peptidase_M19 PF01244.16 KKK18202.1 - 3e-102 341.8 0.0 3.5e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AIG2_2 PF13772.1 KKK18203.1 - 3.3e-08 33.5 0.0 5.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family Zn_clus PF00172.13 KKK18204.1 - 5e-09 35.9 7.3 8.5e-09 35.1 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MaoC_dehydratas PF01575.14 KKK18205.1 - 3.7e-26 90.9 0.0 7.8e-26 89.8 0.0 1.5 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KKK18205.1 - 2.9e-08 33.5 0.0 1.3e-06 28.2 0.0 2.4 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase PepSY PF03413.14 KKK18205.1 - 0.12 13.0 0.1 0.24 12.0 0.1 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Polyketide_cyc2 PF10604.4 KKK18206.1 - 1.5e-08 34.9 0.0 1.7e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MFS_1 PF07690.11 KKK18208.1 - 5e-46 157.0 50.6 2.6e-43 148.1 33.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sulfatase PF00884.18 KKK18209.1 - 9.9e-22 77.4 0.3 1.5e-21 76.8 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KKK18209.1 - 1.4e-05 24.5 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KKK18209.1 - 0.054 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily RHH_4 PF13467.1 KKK18209.1 - 0.096 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain DUF229 PF02995.12 KKK18209.1 - 0.15 10.4 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Serpulina_VSP PF05540.6 KKK18210.1 - 0.012 14.4 0.1 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein DUF1102 PF06510.6 KKK18210.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) Peptidase_S9 PF00326.16 KKK18211.1 - 6.7e-54 182.3 0.0 1e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK18211.1 - 1e-09 38.3 0.0 2.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK18211.1 - 1.5e-08 34.8 0.5 3.8e-08 33.4 0.3 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KKK18211.1 - 0.0052 15.5 0.5 0.0076 15.0 0.3 1.1 1 0 0 1 1 1 1 Carboxylesterase family PD40 PF07676.7 KKK18211.1 - 0.0056 16.3 1.4 1.1 9.0 0.1 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Kri1 PF05178.7 KKK18212.1 - 0.0019 18.4 0.3 0.0023 18.1 0.2 1.1 1 0 0 1 1 1 1 KRI1-like family Pectinesterase PF01095.14 KKK18213.1 - 2.7e-172 571.1 70.9 4.9e-46 156.6 4.7 6.6 6 0 0 6 6 6 5 Pectinesterase DUF1788 PF08747.6 KKK18213.1 - 0.098 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) HSDR_N_2 PF13588.1 KKK18214.1 - 0.0068 16.2 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.15 KKK18214.1 - 0.057 12.9 0.0 0.88 9.0 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Sporozoite_P67 PF05642.6 KKK18214.1 - 0.062 11.1 0.2 0.086 10.6 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen APH PF01636.18 KKK18214.1 - 0.32 10.6 2.8 0.36 10.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Acetyltransf_4 PF13420.1 KKK18216.1 - 1.3e-05 25.2 0.0 3.2e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK18216.1 - 2.1e-05 24.4 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK18216.1 - 0.0017 18.4 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KKK18216.1 - 0.002 18.2 0.0 0.0041 17.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK18216.1 - 0.0046 17.1 0.0 0.0058 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK18216.1 - 0.013 15.3 0.0 0.11 12.3 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Anoctamin PF04547.7 KKK18217.1 - 1.3e-125 419.5 3.1 1.7e-125 419.2 2.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel GST_N_2 PF13409.1 KKK18217.1 - 3.3e-17 62.2 0.0 8.4e-17 60.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK18217.1 - 6e-10 38.8 0.0 1.4e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK18217.1 - 9.3e-06 26.0 0.0 2.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC_membrane PF00664.18 KKK18217.1 - 0.0053 16.2 0.1 0.0053 16.2 0.0 2.6 3 0 0 3 3 3 1 ABC transporter transmembrane region GST_N_3 PF13417.1 KKK18217.1 - 0.031 14.4 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain cNMP_binding PF00027.24 KKK18218.1 - 5.9e-39 131.7 0.3 2.3e-21 75.4 0.0 4.7 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KKK18218.1 - 2.5e-19 70.0 5.8 3.4e-18 66.3 4.0 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase SGT1 PF07093.6 KKK18218.1 - 0.24 9.7 0.0 0.39 9.0 0.0 1.2 1 0 0 1 1 1 0 SGT1 protein Ribonuclease_3 PF00636.21 KKK18219.1 - 1.7e-44 150.9 0.0 1.6e-21 76.8 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KKK18219.1 - 1.9e-29 102.2 0.0 6.1e-15 55.3 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 KKK18219.1 - 1.1e-24 86.0 0.0 2.2e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 KKK18219.1 - 5.5e-18 65.0 0.0 1.3e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK18219.1 - 1.2e-14 53.9 0.0 3.1e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK18219.1 - 1.9e-09 37.6 0.0 4.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit bZIP_1 PF00170.16 KKK18220.1 - 3.3e-09 36.5 10.0 1.3e-08 34.6 6.9 1.9 1 1 0 1 1 1 1 bZIP transcription factor Rab5-bind PF09311.6 KKK18220.1 - 0.005 16.7 1.5 0.011 15.6 1.0 1.5 1 0 0 1 1 1 1 Rabaptin-like protein IncA PF04156.9 KKK18220.1 - 0.045 13.3 0.8 0.066 12.8 0.6 1.3 1 0 0 1 1 1 0 IncA protein Adeno_PIX PF03955.9 KKK18220.1 - 0.053 14.0 1.0 0.053 14.0 0.7 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF501 PF04417.7 KKK18220.1 - 0.074 12.8 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) bZIP_2 PF07716.10 KKK18220.1 - 1.4 8.8 18.1 21 5.0 9.8 2.6 2 1 0 2 2 2 0 Basic region leucine zipper An_peroxidase PF03098.10 KKK18240.1 - 3.8e-89 299.4 0.0 5.4e-70 236.2 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 KKK18240.1 - 4.5e-06 25.4 0.0 0.00076 18.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 TPR_11 PF13414.1 KKK18241.1 - 2.6e-46 155.1 22.4 8.1e-12 44.6 0.8 6.9 3 1 4 8 8 8 7 TPR repeat TPR_1 PF00515.23 KKK18241.1 - 4.8e-36 120.8 23.1 5e-07 29.0 0.0 10.6 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 KKK18241.1 - 5e-35 116.5 23.7 4.8e-06 26.0 0.1 9.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 KKK18241.1 - 1.6e-25 89.1 15.2 3.9e-07 30.5 0.3 5.8 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 KKK18241.1 - 3.6e-23 81.2 21.3 1.3e-07 31.4 0.5 6.5 2 1 5 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 KKK18241.1 - 1.8e-18 64.8 18.9 0.0033 17.1 0.1 9.1 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 KKK18241.1 - 3.4e-15 55.1 12.4 0.038 14.6 0.1 8.7 3 2 6 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 KKK18241.1 - 1.9e-14 52.5 10.5 0.037 14.2 0.0 8.1 9 1 0 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KKK18241.1 - 1.1e-13 49.8 10.3 0.025 14.3 0.1 7.8 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 KKK18241.1 - 3.7e-13 49.1 6.8 1.3e-06 28.1 0.2 5.8 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KKK18241.1 - 4.6e-13 49.2 13.0 2e-05 24.8 0.3 5.8 3 1 4 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 KKK18241.1 - 2e-10 40.6 14.3 0.0045 17.0 0.2 5.3 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KKK18241.1 - 2e-05 23.8 10.1 0.15 11.0 1.3 5.4 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK18241.1 - 5.3e-05 23.4 20.8 3.2 8.4 0.5 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat BLVR PF06375.6 KKK18241.1 - 0.00014 21.6 5.9 0.00031 20.5 4.1 1.5 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) SHNi-TPR PF10516.4 KKK18241.1 - 0.00021 20.4 7.4 0.54 9.5 0.0 5.4 5 0 0 5 5 5 2 SHNi-TPR MAS20 PF02064.10 KKK18241.1 - 0.0018 18.1 8.0 2.9 7.8 1.7 4.3 3 2 1 4 4 4 1 MAS20 protein import receptor TPR_10 PF13374.1 KKK18241.1 - 0.002 18.0 4.2 2.4 8.1 0.3 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat ARL6IP6 PF15062.1 KKK18241.1 - 0.01 15.6 0.1 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix TPR_4 PF07721.9 KKK18241.1 - 0.011 16.1 0.1 30 5.4 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1510 PF07423.6 KKK18241.1 - 0.011 15.1 5.1 0.02 14.2 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NARP1 PF12569.3 KKK18241.1 - 0.014 14.1 17.5 0.42 9.2 0.1 4.2 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 PPP4R2 PF09184.6 KKK18241.1 - 0.02 14.4 3.4 2.4 7.6 2.0 2.2 2 0 0 2 2 2 0 PPP4R2 Sel1 PF08238.7 KKK18241.1 - 0.065 13.8 6.5 0.83 10.3 0.1 3.9 4 0 0 4 4 2 0 Sel1 repeat Apc5 PF12862.2 KKK18241.1 - 0.19 11.6 8.5 14 5.5 0.3 4.4 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 IFT43 PF15305.1 KKK18241.1 - 0.38 10.7 6.3 0.8 9.7 4.4 1.5 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Usp PF00582.21 KKK18241.1 - 9.4 6.4 11.4 2 8.6 1.1 3.3 4 1 0 4 4 3 0 Universal stress protein family Aminotran_4 PF01063.14 KKK18242.1 - 3.4e-39 134.6 0.0 4.3e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV PRELI PF04707.9 KKK18243.1 - 4.4e-22 78.3 0.0 3.8e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family DUF3445 PF11927.3 KKK18245.1 - 2.7e-56 190.7 0.0 3.3e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PALP PF00291.20 KKK18246.1 - 2.1e-70 237.3 1.4 3.1e-70 236.8 0.9 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KKK18246.1 - 1.2e-47 159.3 0.0 2e-24 85.0 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.13 KKK18247.1 - 7.2e-06 25.8 9.9 0.0017 18.3 0.7 2.3 1 1 1 2 2 2 2 Ribosomal protein L36 Aldedh PF00171.17 KKK18248.1 - 2.2e-164 547.1 0.8 2.5e-164 546.9 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KKK18248.1 - 0.00077 18.2 0.0 0.0011 17.7 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KKK18248.1 - 0.12 11.5 0.0 0.57 9.3 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Abhydrolase_1 PF00561.15 KKK18249.1 - 4.6e-18 65.6 0.1 2e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK18249.1 - 2e-11 44.2 0.8 6e-10 39.3 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KKK18249.1 - 0.0001 21.8 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF814 PF05670.8 KKK18250.1 - 6.5e-10 38.7 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Cu-oxidase_3 PF07732.10 KKK18251.1 - 9.6e-10 38.2 0.0 1.8e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK18251.1 - 9.5e-06 25.1 0.0 0.016 14.7 0.0 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK18251.1 - 0.028 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase Mtc PF03820.12 KKK18252.1 - 1.2e-86 290.1 0.2 4e-85 285.1 0.1 2.4 1 1 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.27 KKK18252.1 - 7.4e-28 95.3 14.9 1e-06 28.3 0.2 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat 4HBT_3 PF13622.1 KKK18253.1 - 2.6e-26 92.9 1.7 3e-26 92.6 1.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KKK18253.1 - 3.4e-05 23.4 0.1 0.00043 19.8 0.0 2.4 2 1 1 3 3 3 1 Acyl-CoA thioesterase DUF914 PF06027.7 KKK18254.1 - 2.7e-104 348.6 15.8 3.4e-104 348.3 11.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KKK18254.1 - 0.0047 16.9 27.5 0.01 15.8 7.3 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KKK18254.1 - 3 7.4 21.0 0.095 12.3 3.7 2.6 3 0 0 3 3 3 0 Triose-phosphate Transporter family PIG-U PF06728.8 KKK18255.1 - 3.1e-122 408.1 30.6 3.5e-122 407.9 21.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 KKK18256.1 - 7.5e-115 383.0 0.1 7.5e-115 383.0 0.0 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KKK18256.1 - 1.8e-07 31.2 0.0 6.8e-06 26.1 0.0 3.1 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain SGT1 PF07093.6 KKK18256.1 - 0.00023 19.6 8.8 0.00035 19.1 6.1 1.2 1 0 0 1 1 1 1 SGT1 protein Aldo_ket_red PF00248.16 KKK18257.1 - 2.9e-57 193.6 0.0 3.6e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.19 KKK18258.1 - 1.2e-06 28.4 0.5 2e-06 27.7 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK18258.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Fumarate_red_D PF02313.12 KKK18259.1 - 0.06 13.2 1.7 0.06 13.2 1.2 2.0 1 1 1 2 2 2 0 Fumarate reductase subunit D CMD PF02627.15 KKK18260.1 - 1.1e-08 34.7 0.3 3.3e-08 33.2 0.1 1.9 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family CPSase_L_D3 PF02787.14 KKK18260.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GBP_C PF02841.9 KKK18260.1 - 0.055 12.6 0.1 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Exo_endo_phos PF03372.18 KKK18261.1 - 7.5e-18 65.3 0.2 1.1e-17 64.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2305 PF10230.4 KKK18262.1 - 3.2e-77 259.5 0.0 2.1e-76 256.8 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KKK18262.1 - 5.4e-08 32.9 1.7 5.9e-07 29.6 1.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK18262.1 - 8.9e-06 25.5 0.3 7.4e-05 22.5 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK18262.1 - 0.022 14.3 0.2 0.23 11.0 0.0 2.4 3 1 0 3 3 3 0 alpha/beta hydrolase fold DUF900 PF05990.7 KKK18262.1 - 0.028 13.7 0.1 0.055 12.7 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1057 PF06342.7 KKK18262.1 - 0.032 13.0 0.0 0.71 8.6 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.15 KKK18262.1 - 0.066 13.4 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.8 KKK18262.1 - 0.092 12.3 0.1 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein DCP1 PF06058.8 KKK18263.1 - 1.8e-16 60.3 0.0 1.5e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 Dcp1-like decapping family SMK-1 PF04802.10 KKK18264.1 - 2.4e-75 252.3 1.8 3.9e-75 251.6 1.3 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 GalKase_gal_bdg PF10509.4 KKK18264.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature STE3 PF02076.10 KKK18265.1 - 4.5e-59 199.8 18.5 3.1e-50 170.8 3.6 4.0 1 1 2 3 3 3 3 Pheromone A receptor SSB PF00436.20 KKK18266.1 - 8.2e-19 67.4 0.0 1e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Slp PF03843.8 KKK18266.1 - 0.12 11.3 0.1 6.1 5.8 0.0 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein Slp family Gluconate_2-dh3 PF13618.1 KKK18267.1 - 0.0017 18.4 2.5 0.0042 17.2 1.8 1.6 1 0 0 1 1 1 1 Gluconate 2-dehydrogenase subunit 3 ABC_membrane PF00664.18 KKK18268.1 - 4.2e-75 252.6 30.5 2.7e-38 131.9 8.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KKK18268.1 - 9e-52 175.0 0.0 2.3e-30 105.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KKK18268.1 - 2.3e-09 36.8 4.0 0.0042 16.3 0.8 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KKK18268.1 - 1.3e-06 28.5 0.6 0.01 15.8 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KKK18268.1 - 8.8e-06 25.8 2.9 0.69 9.8 0.0 5.1 4 1 0 5 5 5 1 AAA domain AAA_29 PF13555.1 KKK18268.1 - 9.3e-06 25.0 0.2 0.059 12.8 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KKK18268.1 - 4.9e-05 23.2 0.6 0.61 10.0 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KKK18268.1 - 5.5e-05 22.3 0.0 0.014 14.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KKK18268.1 - 5.6e-05 22.6 0.0 0.17 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KKK18268.1 - 0.00072 19.4 0.5 0.14 12.0 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.1 KKK18268.1 - 0.0017 18.7 0.0 0.22 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KKK18268.1 - 0.0023 18.4 0.7 3.8 8.0 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 KKK18268.1 - 0.0045 16.5 1.8 1.3 8.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK18268.1 - 0.012 15.1 0.0 5.5 6.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 KKK18268.1 - 0.047 13.4 0.4 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 UPF0079 PF02367.12 KKK18268.1 - 0.053 13.1 0.1 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KKK18268.1 - 0.069 12.2 0.2 11 5.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KKK18268.1 - 0.32 11.1 2.0 17 5.5 0.0 3.3 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 KKK18269.1 - 1.5e-57 194.7 0.0 3.3e-57 193.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18269.1 - 2.3e-26 92.4 0.0 5.9e-23 81.2 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 KKK18269.1 - 7.4e-10 38.8 0.0 1.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KKK18269.1 - 2.7e-05 23.2 0.0 4.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK18269.1 - 9.1e-05 22.2 1.7 0.0027 17.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK18269.1 - 0.00011 21.3 0.0 0.00025 20.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KKK18269.1 - 0.0052 16.1 0.5 0.01 15.1 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL DUF2939 PF11159.3 KKK18269.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Myb_DNA-bind_6 PF13921.1 KKK18270.1 - 0.00015 21.7 0.1 0.00026 21.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK18270.1 - 0.0025 17.8 0.2 0.006 16.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PRCC PF10253.4 KKK18270.1 - 0.31 11.7 3.3 1 10.0 0.0 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Adap_comp_sub PF00928.16 KKK18271.1 - 1.5e-85 286.5 0.0 2e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KKK18271.1 - 0.0002 21.0 0.1 0.00035 20.3 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KKK18271.1 - 0.029 13.5 0.1 0.047 12.8 0.1 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF4203 PF13886.1 KKK18272.1 - 6.3e-45 153.2 21.4 8.3e-45 152.8 14.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.4 KKK18272.1 - 3.4e-32 110.7 0.0 6.6e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family 23S_rRNA_IVP PF05635.6 KKK18272.1 - 0.074 12.9 1.6 0.2 11.5 1.1 1.7 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein Ldh_1_N PF00056.18 KKK18272.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain PgaD PF13994.1 KKK18272.1 - 0.13 11.7 0.1 0.41 10.1 0.1 1.8 1 0 0 1 1 1 0 PgaD-like protein Ank_5 PF13857.1 KKK18273.1 - 0.0024 18.0 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KKK18273.1 - 0.0065 16.2 0.2 0.016 14.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat zf-C2H2_2 PF12756.2 KKK18273.1 - 0.016 15.3 0.3 0.034 14.2 0.2 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ank_4 PF13637.1 KKK18273.1 - 0.035 14.6 0.0 0.079 13.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF3077 PF11275.3 KKK18273.1 - 0.061 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) Ank_2 PF12796.2 KKK18273.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Guanylate_kin PF00625.16 KKK18274.1 - 1e-22 80.4 0.1 1.1e-22 80.3 0.1 1.0 1 0 0 1 1 1 1 Guanylate kinase AA_permease PF00324.16 KKK18275.1 - 2.9e-128 428.2 35.5 3.5e-128 427.9 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK18275.1 - 3.8e-37 127.8 41.4 4.9e-37 127.4 28.7 1.2 1 0 0 1 1 1 1 Amino acid permease NicO PF03824.11 KKK18277.1 - 1.1e-57 195.5 17.1 9.4e-56 189.1 3.5 2.6 3 0 0 3 3 3 2 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 KKK18277.1 - 0.048 12.4 6.8 0.14 10.9 1.6 2.2 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion 2Fe-2S_thioredx PF01257.14 KKK18279.1 - 7e-21 74.3 0.0 9.3e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin A_deaminase PF00962.17 KKK18280.1 - 5.6e-75 252.3 0.0 6.3e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 KKK18280.1 - 0.00026 21.1 0.1 0.00063 19.8 0.1 1.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KKK18280.1 - 0.039 13.1 0.1 0.078 12.1 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase family TFCD_C PF12612.3 KKK18297.1 - 1.6e-38 132.1 2.5 3.7e-36 124.3 0.2 3.1 3 0 0 3 3 3 2 Tubulin folding cofactor D C terminal RRM_1 PF00076.17 KKK18297.1 - 1.2e-11 44.0 0.3 2.9e-11 42.8 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18297.1 - 3.1e-09 36.5 0.0 6.7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK18297.1 - 2.3e-06 27.5 0.1 7.1e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HEAT_2 PF13646.1 KKK18297.1 - 2e-05 24.7 9.3 0.047 13.9 0.1 5.5 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KKK18297.1 - 6.8e-05 22.6 9.1 0.19 11.9 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 KKK18297.1 - 0.0083 16.5 7.5 0.75 10.3 0.1 5.7 6 0 0 6 6 6 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KKK18297.1 - 0.069 13.5 0.0 0.59 10.5 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HMG_CoA_synt_N PF01154.12 KKK18297.1 - 0.16 11.5 0.0 1.6 8.2 0.0 2.5 3 0 0 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal HEAT_PBS PF03130.11 KKK18297.1 - 0.17 12.4 1.8 64 4.4 0.0 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat HR1 PF02185.11 KKK18300.1 - 3.7e-34 116.2 12.7 3.5e-19 68.2 3.2 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KKK18300.1 - 3.3e-21 74.7 28.4 1.1e-11 44.2 6.4 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) UPF0547 PF10571.4 KKK18300.1 - 0.16 11.7 8.5 3.8 7.3 0.1 3.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Uds1 PF15456.1 KKK18300.1 - 1.5 8.8 6.3 0.38 10.7 0.7 2.3 2 0 0 2 2 2 0 Up-regulated During Septation FYVE_2 PF02318.11 KKK18300.1 - 3.5 7.5 19.1 1.8 8.4 3.9 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger DUF2076 PF09849.4 KKK18300.1 - 5.3 7.0 10.1 4.3 7.3 4.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Fungal_trans PF04082.13 KKK18301.1 - 1.4e-18 66.7 0.1 2.7e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK18301.1 - 2.5e-08 33.7 8.9 4.8e-08 32.7 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KKK18302.1 - 5.4e-17 61.8 0.2 1.7e-07 30.6 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KKK18302.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KKK18302.1 - 0.0014 17.5 0.0 0.029 13.1 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.1 KKK18302.1 - 0.0073 16.3 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK18302.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Myb_DNA-binding PF00249.26 KKK18303.1 - 2.7e-31 107.3 11.1 1.6e-11 44.0 0.8 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK18303.1 - 3.9e-29 100.5 8.9 5.6e-16 58.3 1.2 3.2 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KKK18303.1 - 0.013 15.5 11.9 1.5 8.9 0.5 3.8 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 KKK18303.1 - 0.024 14.4 1.6 7 6.5 0.0 3.1 2 1 1 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_5 PF13873.1 KKK18303.1 - 0.13 12.1 9.4 33 4.4 0.0 5.1 3 3 2 5 5 5 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 KKK18303.1 - 1.9 8.4 4.0 3 7.7 0.7 2.6 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Lipase_GDSL_2 PF13472.1 KKK18304.1 - 1e-09 38.7 0.6 2.5e-09 37.4 0.2 1.8 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KKK18304.1 - 1.7e-05 24.7 0.1 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KKK18304.1 - 0.00061 19.5 0.0 0.0013 18.5 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Ank_2 PF12796.2 KKK18305.1 - 1.5e-42 143.8 0.1 8.3e-21 74.1 0.0 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KKK18305.1 - 2.7e-39 131.0 1.1 1.3e-07 31.0 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KKK18305.1 - 2.4e-34 116.5 6.8 5.9e-10 39.0 0.1 6.1 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK18305.1 - 4.1e-27 94.0 2.9 8.7e-06 26.1 0.0 6.2 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK18305.1 - 4.9e-26 88.1 0.4 0.00044 20.2 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat F-box-like PF12937.2 KKK18305.1 - 0.033 13.9 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like Zn_clus PF00172.13 KKK18307.1 - 6.4e-08 32.3 10.0 6.4e-08 32.3 6.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_31 PF13847.1 KKK18308.1 - 1.4e-26 92.9 0.0 1.8e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18308.1 - 4.3e-24 84.8 0.0 6.5e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK18308.1 - 3.4e-16 59.0 0.0 4.7e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KKK18308.1 - 2.3e-15 56.8 0.0 3.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18308.1 - 2.9e-15 56.7 0.0 5.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18308.1 - 4.2e-15 55.9 0.0 7.1e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK18308.1 - 2.1e-14 53.5 0.0 2.6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK18308.1 - 3.9e-10 39.7 0.1 6.8e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KKK18308.1 - 3e-09 36.5 0.0 4.4e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KKK18308.1 - 1.5e-08 34.4 0.0 2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KKK18308.1 - 9.9e-07 28.2 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 KKK18308.1 - 1.6e-05 23.9 0.0 2.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 KKK18308.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KKK18308.1 - 0.00024 19.9 0.0 0.00033 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 KKK18308.1 - 0.00034 19.7 0.0 0.00045 19.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 KKK18308.1 - 0.0013 17.1 0.0 0.0017 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 KKK18308.1 - 0.003 16.6 0.0 0.0038 16.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 KKK18308.1 - 0.035 13.1 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PLDc_2 PF13091.1 KKK18333.1 - 1.6e-13 50.4 0.0 1e-05 25.2 0.0 3.3 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 KKK18333.1 - 1.6e-11 43.6 2.5 4.6e-05 23.0 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 KKK18333.1 - 0.27 10.1 0.1 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB DEAD PF00270.24 KKK18334.1 - 2.7e-18 66.0 0.0 5.5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KKK18334.1 - 1.4e-07 31.5 0.0 8e-07 29.0 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK18334.1 - 3.7e-06 26.6 0.2 9.3e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 KKK18334.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Cyanate_lyase PF02560.9 KKK18335.1 - 2.3e-23 81.5 0.0 5.3e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain zf-C2H2_4 PF13894.1 KKK18335.1 - 2.9e-09 36.5 14.3 0.33 11.4 0.0 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK18335.1 - 9.2e-09 35.1 17.7 0.15 12.4 0.1 6.1 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-Di19 PF05605.7 KKK18335.1 - 7.3e-06 26.0 8.8 0.051 13.7 1.7 3.7 2 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 KKK18335.1 - 2.8e-05 24.1 12.4 0.34 11.2 0.2 4.6 4 0 0 4 4 4 2 Zinc-finger double domain Rad50_zn_hook PF04423.9 KKK18335.1 - 0.00011 21.6 14.4 0.00018 20.9 0.1 4.9 3 1 2 5 5 5 1 Rad50 zinc hook motif zf-C2H2_jaz PF12171.3 KKK18335.1 - 0.0013 18.8 8.8 4.5 7.5 0.4 5.9 5 1 1 6 6 6 1 Zinc-finger double-stranded RNA-binding zf-RING_4 PF14570.1 KKK18335.1 - 0.002 17.6 10.5 5.2 6.7 0.1 4.5 4 0 0 4 4 4 1 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 KKK18335.1 - 0.004 16.6 11.0 3.4 7.3 0.1 4.0 3 1 0 3 3 3 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KKK18335.1 - 0.0046 16.6 10.9 4.6 7.0 0.1 4.0 3 1 0 3 3 3 3 zinc-ribbon domain DUF2225 PF09986.4 KKK18335.1 - 0.014 14.8 8.7 0.1 12.0 0.0 3.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 KKK18335.1 - 0.017 14.9 16.1 4.7 7.2 0.0 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger GAGA PF09237.6 KKK18335.1 - 0.057 13.0 3.5 0.066 12.8 0.0 2.6 3 0 0 3 3 3 0 GAGA factor Zn-ribbon_8 PF09723.5 KKK18335.1 - 0.076 12.9 13.3 0.59 10.1 1.7 4.4 3 1 1 4 4 4 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 KKK18335.1 - 0.11 12.3 0.1 0.11 12.3 0.1 3.1 3 1 0 3 3 2 0 PhnA Zinc-Ribbon zf-met PF12874.2 KKK18335.1 - 0.14 12.3 8.8 14 6.0 0.0 5.0 6 0 0 6 6 5 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KKK18335.1 - 0.28 10.8 8.4 3.3 7.4 0.1 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KKK18335.1 - 0.34 11.0 13.6 3.8 7.6 2.1 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CSL PF05207.8 KKK18335.1 - 0.5 9.9 8.1 0.84 9.1 0.2 3.0 3 0 0 3 3 3 0 CSL zinc finger zf-RING_3 PF14369.1 KKK18335.1 - 0.57 10.2 9.2 18 5.4 0.2 4.3 4 0 0 4 4 4 0 zinc-finger CpXC PF14353.1 KKK18335.1 - 0.97 9.4 11.7 10 6.0 0.1 4.0 2 1 3 5 5 5 0 CpXC protein DZR PF12773.2 KKK18335.1 - 1.6 8.6 15.8 4.3 7.2 5.7 3.4 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 KKK18335.1 - 3.9 7.3 13.2 1.3 8.8 0.3 3.7 3 1 2 5 5 4 0 zinc-ribbons UPF0547 PF10571.4 KKK18335.1 - 4.4 7.0 13.9 0.81 9.4 0.9 4.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 IBR PF01485.16 KKK18335.1 - 6.2 6.7 15.6 0.22 11.4 1.3 3.8 2 2 1 3 3 3 0 IBR domain zf-C3HC4_3 PF13920.1 KKK18335.1 - 8 6.2 10.0 6.2 6.5 1.0 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Homeobox PF00046.24 KKK18336.1 - 8.9e-20 70.0 4.5 2e-19 68.9 3.1 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KKK18336.1 - 0.0009 18.8 1.0 0.002 17.7 0.7 1.6 1 0 0 1 1 1 1 Homeobox KN domain PGP_phosphatase PF09419.5 KKK18337.1 - 5e-58 195.1 0.0 6.8e-58 194.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KKK18337.1 - 2.4e-06 27.1 0.0 4.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KKK18337.1 - 0.043 14.0 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK18337.1 - 0.087 13.2 0.5 2.1 8.6 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase LSM PF01423.17 KKK18338.1 - 0.017 14.6 0.1 0.02 14.4 0.1 1.1 1 0 0 1 1 1 0 LSM domain SM-ATX PF14438.1 KKK18338.1 - 0.088 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Dus PF01207.12 KKK18339.1 - 1.8e-54 184.6 0.0 2.9e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 KKK18339.1 - 0.016 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase CENP-X PF09415.5 KKK18340.1 - 1.1e-14 53.9 0.9 1.2e-11 44.2 0.1 2.5 1 1 1 2 2 2 2 CENP-S associating Centromere protein X Dicty_REP PF05086.7 KKK18340.1 - 0.74 7.5 8.1 0.77 7.4 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.8 KKK18340.1 - 2.4 7.9 7.7 2.8 7.7 5.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.4 KKK18340.1 - 4.4 5.8 7.6 4.8 5.7 5.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macro PF01661.16 KKK18341.1 - 3e-10 40.0 0.0 1.2e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 Macro domain Claudin_2 PF13903.1 KKK18342.1 - 0.00056 19.6 8.2 0.36 10.5 1.9 3.5 1 1 3 4 4 4 3 PMP-22/EMP/MP20/Claudin tight junction DUF4395 PF14340.1 KKK18342.1 - 0.0083 16.1 1.9 0.0083 16.1 1.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4395) DUF3611 PF12263.3 KKK18342.1 - 0.01 15.2 0.2 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DUF202 PF02656.10 KKK18342.1 - 0.12 12.6 10.8 3 8.1 5.7 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF2946 PF11162.3 KKK18342.1 - 0.2 11.8 2.5 0.62 10.2 1.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) MARVEL PF01284.18 KKK18342.1 - 0.46 10.3 5.1 1.6 8.5 3.6 1.9 1 1 0 1 1 1 0 Membrane-associating domain zf-C2H2 PF00096.21 KKK18343.1 - 6.2e-08 32.5 11.9 0.00054 20.1 2.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK18343.1 - 1.4e-05 25.0 11.0 0.00091 19.4 1.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK18343.1 - 1.5e-05 25.0 4.3 1.5e-05 25.0 3.0 4.1 5 0 0 5 5 5 1 Zinc-finger double domain BCNT PF07572.7 KKK18344.1 - 5e-28 96.8 0.3 5e-28 96.8 0.2 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development Glyco_hydro_28 PF00295.12 KKK18346.1 - 2.1e-111 371.9 17.5 2.4e-111 371.7 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Ribonuclease_T2 PF00445.13 KKK18347.1 - 6.1e-35 120.5 1.2 9.5e-35 119.9 0.8 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1792 PF08759.6 KKK18347.1 - 0.045 13.3 0.4 0.082 12.5 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1792) Mis12 PF05859.7 KKK18348.1 - 1e-44 151.8 0.0 2e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 Mis12 protein PGC7_Stella PF15549.1 KKK18348.1 - 2 8.3 4.8 2.7 7.9 0.9 2.2 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain Amidohydro_4 PF13147.1 KKK18349.1 - 2.4e-10 40.8 0.0 3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KKK18349.1 - 1.7e-07 31.1 0.1 3.3e-07 30.1 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KKK18349.1 - 0.00062 19.5 0.1 0.0031 17.1 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family bZIP_1 PF00170.16 KKK18350.1 - 2.4e-06 27.4 0.7 4.8e-06 26.4 0.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor Chorion_2 PF03964.10 KKK18350.1 - 0.033 14.7 2.4 0.033 14.7 1.6 2.1 2 0 0 2 2 2 0 Chorion family 2 DUF3446 PF11928.3 KKK18350.1 - 0.56 10.4 7.6 0.22 11.7 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF504 PF04457.7 KKK18351.1 - 1.6e-10 41.0 0.3 3.5e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) MIF PF01187.13 KKK18351.1 - 4.6e-07 29.9 0.4 7.2e-07 29.2 0.3 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Glyco_hydro_76 PF03663.9 KKK18355.1 - 3.9e-148 493.7 20.8 5e-148 493.4 14.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cytokin_check_N PF10407.4 KKK18356.1 - 1e-05 25.0 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus 4HB_MCP_1 PF12729.2 KKK18356.1 - 0.032 13.5 7.6 0.057 12.7 5.3 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction LUC7 PF03194.10 KKK18356.1 - 0.035 13.6 4.3 0.088 12.3 3.0 1.6 1 0 0 1 1 1 0 LUC7 N_terminus Pro_isomerase PF00160.16 KKK18357.1 - 2.1e-51 174.1 0.1 4.1e-51 173.2 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KKK18357.1 - 2.5e-16 58.8 0.6 1.8e-05 24.4 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 KKK18358.1 - 2.6e-133 445.2 10.5 3e-133 444.9 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Toxin_51 PF15531.1 KKK18358.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 51 PAD_M PF08527.5 KKK18358.1 - 0.095 12.0 0.2 0.87 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain GARS_C PF02843.11 KKK18358.1 - 0.12 12.6 0.6 0.96 9.6 0.1 2.7 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain CO_deh_flav_C PF03450.12 KKK18358.1 - 0.18 11.7 1.8 1.4 8.9 0.1 2.7 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Isochorismatase PF00857.15 KKK18359.1 - 4e-23 82.2 0.1 4.7e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Ank_2 PF12796.2 KKK18360.1 - 5.2e-46 154.9 0.0 2.6e-10 40.4 0.0 5.0 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KKK18360.1 - 2.8e-34 115.2 12.3 0.0013 18.4 0.0 9.9 9 1 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 KKK18360.1 - 1.5e-30 105.0 6.7 6.2e-06 26.5 0.0 7.8 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK18360.1 - 2.1e-24 85.0 9.9 2.4e-07 30.7 0.0 7.3 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK18360.1 - 1.6e-22 77.2 6.4 0.0058 16.7 0.0 9.8 10 1 0 10 10 10 5 Ankyrin repeat AlgF PF11182.3 KKK18360.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF Fungal_trans PF04082.13 KKK18361.1 - 4.9e-18 64.9 1.5 1.2e-14 53.7 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK18361.1 - 1.9e-09 37.2 11.8 3.6e-09 36.3 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.12 KKK18361.1 - 0.19 11.4 23.7 0.5 10.1 16.4 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein MSP1_C PF07462.6 KKK18361.1 - 1.6 7.0 1.6 2.9 6.1 1.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus FAD_binding_7 PF03441.9 KKK18362.1 - 6.9e-102 340.3 0.6 1.1e-101 339.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KKK18362.1 - 9e-42 142.6 0.3 1.6e-41 141.7 0.2 1.4 1 0 0 1 1 1 1 DNA photolyase Aminotran_4 PF01063.14 KKK18363.1 - 8.3e-22 77.7 0.0 1.3e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Glyco_transf_90 PF05686.7 KKK18390.1 - 5.6e-23 81.2 0.1 7e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KKK18390.1 - 0.042 14.1 0.2 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 p450 PF00067.17 KKK18391.1 - 4.5e-51 173.8 0.0 7.3e-51 173.1 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 TPR_11 PF13414.1 KKK18392.1 - 5.7e-28 96.3 17.9 2.1e-07 30.4 0.0 8.0 6 2 1 8 8 8 6 TPR repeat TPR_1 PF00515.23 KKK18392.1 - 2.5e-27 93.3 4.4 0.00038 19.9 0.2 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 KKK18392.1 - 4.4e-26 88.6 16.2 0.0035 17.1 0.2 10.6 11 0 0 11 11 10 7 Tetratricopeptide repeat Apc3 PF12895.2 KKK18392.1 - 1.1e-23 83.1 16.2 9.8e-20 70.4 0.5 6.0 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KKK18392.1 - 4.4e-17 62.1 13.5 1e-05 25.7 0.1 7.4 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KKK18392.1 - 3.1e-16 59.0 25.1 5.4e-09 35.8 0.1 8.9 8 2 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK18392.1 - 3.5e-16 59.3 25.8 6.4e-05 23.5 0.3 8.8 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 KKK18392.1 - 4.8e-15 54.6 18.0 0.23 12.2 0.2 10.3 7 2 3 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK18392.1 - 3.6e-14 51.3 0.0 0.05 13.3 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK18392.1 - 1.7e-09 37.0 1.5 0.29 11.4 0.0 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 KKK18392.1 - 2e-08 33.9 18.4 0.0047 16.8 0.1 7.9 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK18392.1 - 1.6e-07 30.5 18.2 1.5 8.7 0.0 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 KKK18392.1 - 3.6e-07 30.2 7.2 1.8 9.1 0.1 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 KKK18392.1 - 0.00036 20.6 25.0 0.02 15.2 0.1 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat RPN7 PF10602.4 KKK18392.1 - 0.1 11.9 0.0 36 3.6 0.0 3.7 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_21 PF09976.4 KKK18392.1 - 0.14 12.1 5.7 39 4.1 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK18392.1 - 0.67 9.8 19.5 17 5.3 0.1 6.2 6 2 1 7 7 7 0 Tetratricopeptide repeat DUF572 PF04502.8 KKK18393.1 - 4.4e-72 243.0 19.8 5.2e-72 242.7 13.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 KKK18393.1 - 0.16 11.5 1.5 0.78 9.4 0.2 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FAT PF02259.18 KKK18394.1 - 2.1e-72 244.0 10.3 4.2e-72 243.0 7.1 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KKK18394.1 - 1.8e-30 106.1 0.4 5.8e-30 104.4 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KKK18394.1 - 3.8e-08 32.6 0.1 1.1e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 FATC domain Tau95 PF09734.4 KKK18405.1 - 2.4e-78 263.5 0.0 3e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit PfkB PF00294.19 KKK18406.1 - 1.9e-12 46.9 0.3 3.2e-12 46.2 0.2 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PfkB PF00294.19 KKK18407.1 - 2e-20 73.1 0.0 2.4e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HSDR_N_2 PF13588.1 KKK18407.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Vps54 PF07928.7 KKK18408.1 - 2.4e-48 163.7 0.3 6.2e-48 162.3 0.1 1.9 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KKK18408.1 - 3.1e-07 29.5 0.6 7.7e-07 28.2 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) LUC7 PF03194.10 KKK18408.1 - 0.053 13.0 2.4 0.049 13.1 0.4 1.8 2 0 0 2 2 2 0 LUC7 N_terminus MCM PF00493.18 KKK18409.1 - 2.2e-140 467.1 0.1 2.9e-140 466.8 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KKK18409.1 - 2.7e-19 69.8 0.3 9.1e-19 68.1 0.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KKK18409.1 - 5.5e-06 25.6 0.0 0.00071 18.7 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK18409.1 - 4.6e-05 23.1 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK18409.1 - 0.0014 18.2 0.1 0.0053 16.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KKK18409.1 - 0.034 14.5 0.3 0.12 12.7 0.2 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KKK18409.1 - 0.063 12.7 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain adh_short PF00106.20 KKK18410.1 - 8.5e-17 61.5 0.0 2.3e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK18410.1 - 8.8e-09 35.2 0.0 1.3e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK18410.1 - 2.4e-06 27.4 0.0 5.5e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KKK18410.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GMC_oxred_N PF00732.14 KKK18411.1 - 2.4e-60 204.2 0.0 2.9e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK18411.1 - 2.2e-30 105.8 0.0 3.9e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KKK18411.1 - 2.1e-07 30.2 1.4 0.00074 18.5 0.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK18411.1 - 4.1e-06 25.9 0.5 0.038 12.8 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KKK18411.1 - 0.0022 18.0 0.2 0.0068 16.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK18411.1 - 0.0034 16.3 0.3 0.0061 15.5 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KKK18411.1 - 0.039 13.0 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KKK18411.1 - 0.097 12.7 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_DMAT PF11991.3 KKK18412.1 - 5.1e-86 289.1 0.0 3.7e-85 286.2 0.0 1.9 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase APH PF01636.18 KKK18432.1 - 6.7e-13 48.9 0.0 3.5e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK18432.1 - 0.032 13.7 3.1 0.043 13.3 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Frag1 PF10277.4 KKK18452.1 - 8.9e-44 149.5 6.8 8.9e-44 149.5 4.7 2.8 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 KKK18452.1 - 0.00013 22.0 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.17 KKK18453.1 - 8.3e-10 38.1 0.0 1.5e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK18453.1 - 8.5e-08 32.0 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18453.1 - 0.074 12.9 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.12 KKK18455.1 - 4.2e-23 81.1 5.1 6.8e-23 80.4 3.5 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 KKK18455.1 - 0.066 13.3 0.9 0.16 12.1 0.6 1.7 1 1 0 1 1 1 0 Prolamin-like Bromo_MP PF01573.11 KKK18455.1 - 0.16 10.9 2.3 1.3 7.9 0.1 2.0 2 0 0 2 2 2 0 Bromovirus movement protein SYS1 PF09801.4 KKK18456.1 - 1.8e-47 160.9 10.8 3.9e-47 159.8 7.5 1.5 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 KKK18456.1 - 4.3 7.1 13.2 0.61 9.8 5.6 2.1 1 1 2 3 3 3 0 Protein of unknown function, DUF485 Aldolase_II PF00596.16 KKK18457.1 - 6.3e-41 140.0 0.1 1.2e-40 139.0 0.1 1.5 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain COG5 PF10392.4 KKK18458.1 - 9e-41 138.9 3.8 2.3e-40 137.6 0.2 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.4 KKK18458.1 - 0.25 11.1 1.4 0.47 10.3 0.3 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 U3_assoc_6 PF08640.6 KKK18459.1 - 2.3e-30 104.1 0.7 4.1e-30 103.3 0.5 1.4 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 KKK18459.1 - 0.0042 17.5 0.1 0.15 12.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.9 KKK18459.1 - 1.3 8.6 5.6 15 5.2 0.2 2.8 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) RF-1 PF00472.15 KKK18460.1 - 1.7e-14 53.5 0.5 2.5e-14 53.0 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain DUF4391 PF14335.1 KKK18460.1 - 0.066 12.5 0.9 0.092 12.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Arginase PF00491.16 KKK18463.1 - 2.3e-74 250.1 0.0 3e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KKK18463.1 - 0.0019 18.4 0.1 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.17 KKK18464.1 - 3.5e-52 176.0 0.0 4.1e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK18464.1 - 5.3e-16 59.1 0.0 8.8e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK18464.1 - 3.6e-06 26.3 0.0 4.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family JAB PF01398.16 KKK18466.1 - 3.3e-35 120.2 0.0 6.9e-35 119.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KKK18466.1 - 1.4e-26 92.8 3.3 2.4e-26 92.0 2.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KKK18466.1 - 5.1e-09 35.6 0.0 8.9e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 KKK18466.1 - 0.02 14.6 0.5 0.044 13.5 0.2 1.7 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Hist_deacetyl PF00850.14 KKK18467.1 - 1.7e-78 264.0 0.0 2.9e-78 263.3 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain NIF PF03031.13 KKK18468.1 - 1.2e-40 138.7 0.1 1.7e-40 138.2 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KKK18468.1 - 0.067 13.4 0.3 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ribosomal_L14 PF00238.14 KKK18470.1 - 5.2e-34 116.6 0.0 5.7e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Nucleoporin_C PF03177.9 KKK18471.1 - 1.2e-121 407.1 6.7 1.5e-121 406.8 4.6 1.0 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal VWA_2 PF13519.1 KKK18471.1 - 0.03 14.4 0.0 0.24 11.4 0.0 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain R3H PF01424.17 KKK18473.1 - 3.1e-12 46.0 0.3 7.2e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 R3H domain G-patch PF01585.18 KKK18473.1 - 3.3e-10 39.5 0.2 8.4e-10 38.2 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KKK18473.1 - 2.3e-05 24.1 0.1 7.4e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-C2H2_jaz PF12171.3 KKK18474.1 - 5e-11 42.4 14.0 6.2e-10 38.9 3.5 2.9 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK18474.1 - 7.7e-11 41.8 9.6 1.6e-08 34.4 1.8 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KKK18474.1 - 3.1e-06 27.2 8.9 0.00041 20.4 1.0 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KKK18474.1 - 5.8e-05 23.1 8.8 0.035 14.4 0.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK18474.1 - 0.0009 19.4 15.4 0.032 14.5 0.6 3.2 4 0 0 4 4 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KKK18474.1 - 0.0013 18.5 10.2 0.23 11.4 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.17 KKK18474.1 - 0.015 15.3 3.2 0.17 11.9 0.3 2.4 2 0 0 2 2 2 0 LIM domain zf-H2C2_2 PF13465.1 KKK18474.1 - 0.055 13.7 7.3 0.35 11.2 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain CpXC PF14353.1 KKK18474.1 - 0.11 12.4 5.6 3.4 7.6 0.0 3.0 3 0 0 3 3 3 0 CpXC protein DUF16 PF01519.11 KKK18474.1 - 0.19 11.9 2.6 5.5 7.2 1.8 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 C1_4 PF07975.7 KKK18474.1 - 0.21 11.6 3.5 6.1 6.9 0.1 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Mut7-C PF01927.11 KKK18474.1 - 0.48 10.4 5.9 0.76 9.7 1.6 2.2 2 0 0 2 2 2 0 Mut7-C RNAse domain zf-LYAR PF08790.6 KKK18474.1 - 0.99 9.1 5.0 0.44 10.2 0.5 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_4 PF13717.1 KKK18474.1 - 1.4 8.7 5.8 0.4 10.4 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.7 KKK18474.1 - 1.7 8.7 6.7 3.5 7.8 0.1 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.1 KKK18474.1 - 1.9 8.1 5.6 0.66 9.6 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PhoD PF09423.5 KKK18502.1 - 6.3e-13 48.1 0.0 1.9e-08 33.3 0.1 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.17 KKK18503.1 - 9.3e-24 84.1 7.2 1.9e-23 83.1 5.0 1.5 1 0 0 1 1 1 1 Rhomboid family TRM PF02005.11 KKK18504.1 - 1.6e-111 372.9 0.0 3.6e-97 325.6 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 KKK18504.1 - 0.00034 20.2 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 KKK18504.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Pex14_N PF04695.8 KKK18504.1 - 0.27 11.2 5.0 1.3 9.0 0.2 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1691 PF07950.6 KKK18505.1 - 9.9e-54 179.9 7.4 9.1e-36 122.1 2.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 KKK18505.1 - 0.0076 16.0 6.5 1.1 9.1 0.0 2.5 2 1 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit adh_short_C2 PF13561.1 KKK18506.1 - 1.6e-21 77.2 0.0 4.2e-20 72.5 0.0 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 KKK18506.1 - 1.2e-20 74.0 0.0 2.7e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 KKK18506.1 - 1.1e-18 67.1 0.0 2.4e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KKK18506.1 - 7.4e-12 45.1 0.0 1.8e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KKK18506.1 - 2.6e-06 27.4 0.0 6.7e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK18506.1 - 0.00066 19.3 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 KR domain DUF1031 PF06275.6 KKK18506.1 - 0.12 12.4 0.1 9.7 6.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) zf-C2H2 PF00096.21 KKK18507.1 - 0.0022 18.2 1.8 0.0044 17.2 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK18507.1 - 0.004 17.2 3.4 0.0065 16.5 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK18507.1 - 0.0049 17.0 0.7 0.0081 16.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KKK18507.1 - 0.012 15.8 0.6 0.025 14.8 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KKK18507.1 - 0.028 14.3 0.9 0.046 13.6 0.6 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KKK18507.1 - 0.035 14.2 0.4 0.056 13.5 0.3 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) UPF0240 PF06784.6 KKK18507.1 - 0.1 12.2 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Transket_pyr PF02779.19 KKK18508.1 - 1.3e-45 155.0 0.0 1.9e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KKK18508.1 - 1.9e-36 124.7 0.0 7.9e-36 122.7 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Metallophos PF00149.23 KKK18509.1 - 7.2e-09 35.3 5.6 7.8e-09 35.2 3.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.21 KKK18510.1 - 1.6e-11 43.8 0.0 3.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 KKK18510.1 - 0.0032 17.4 0.5 0.0054 16.6 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.7 KKK18510.1 - 0.0072 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain KR PF08659.5 KKK18510.1 - 0.019 14.6 0.3 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 KR domain DUF4265 PF14085.1 KKK18510.1 - 0.04 13.6 0.0 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Amidase PF01425.16 KKK18511.1 - 6.7e-115 384.4 0.2 8e-115 384.1 0.1 1.0 1 0 0 1 1 1 1 Amidase DAO PF01266.19 KKK18512.1 - 6.4e-28 97.6 0.0 7.9e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK18512.1 - 0.0004 20.3 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK18512.1 - 0.011 14.8 1.8 0.014 14.4 0.0 2.1 2 0 0 2 2 2 0 Thi4 family COPI_assoc PF08507.5 KKK18513.1 - 4.3e-44 149.5 8.2 5.5e-44 149.2 5.7 1.1 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 KKK18513.1 - 4.3 7.3 10.9 14 5.6 7.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein CG6151-P Rhomboid PF01694.17 KKK18513.1 - 8.5 6.3 15.0 12 5.8 10.4 1.1 1 0 0 1 1 1 0 Rhomboid family ubiquitin PF00240.18 KKK18522.1 - 2.4e-34 116.5 0.9 4e-34 115.8 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KKK18522.1 - 9e-20 70.1 0.7 1.5e-19 69.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.14 KKK18522.1 - 3.2e-09 36.4 0.0 7.4e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.1 KKK18522.1 - 1.4e-05 25.2 0.2 5.7e-05 23.2 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KKK18522.1 - 9.7e-05 22.1 0.1 0.00026 20.7 0.0 1.7 2 0 0 2 2 2 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KKK18522.1 - 0.0016 18.3 0.5 0.0035 17.1 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KKK18522.1 - 0.0054 16.8 0.4 0.0081 16.3 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.7 KKK18522.1 - 0.058 11.7 0.2 5.6 5.1 0.0 2.1 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2870 PF11069.3 KKK18522.1 - 0.12 12.4 0.5 0.21 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) zf-C2H2_4 PF13894.1 KKK18523.1 - 0.023 15.0 1.8 0.07 13.4 1.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK18523.1 - 0.28 11.6 3.0 0.68 10.3 2.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type SRP54 PF00448.17 KKK18524.1 - 8.8e-75 250.4 3.5 1.5e-74 249.7 2.4 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KKK18524.1 - 4.4e-24 84.7 0.5 4.4e-24 84.7 0.3 4.3 5 1 0 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 KKK18524.1 - 6.4e-17 61.4 0.4 1.4e-16 60.3 0.3 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KKK18524.1 - 5.2e-09 35.7 0.2 1.2e-08 34.6 0.2 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KKK18524.1 - 1.4e-06 28.1 0.2 4.5e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK18524.1 - 3.1e-05 24.7 0.0 6.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KKK18524.1 - 5.5e-05 22.8 0.1 0.00015 21.5 0.0 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 KKK18524.1 - 0.00011 22.1 0.0 0.17 11.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain CbiA PF01656.18 KKK18524.1 - 0.00021 20.7 0.2 0.00069 19.0 0.2 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.15 KKK18524.1 - 0.00096 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 KKK18524.1 - 0.0011 18.1 0.1 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ArgK PF03308.11 KKK18524.1 - 0.0016 17.2 0.0 0.0016 17.2 0.0 2.4 3 1 1 4 4 4 1 ArgK protein SRPRB PF09439.5 KKK18524.1 - 0.0018 17.4 1.2 1.2 8.3 0.7 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KKK18524.1 - 0.0019 18.1 0.1 0.0074 16.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK18524.1 - 0.0056 16.8 0.0 0.019 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK18524.1 - 0.0083 16.4 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 KKK18524.1 - 0.0093 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ATP_bind_1 PF03029.12 KKK18524.1 - 0.013 15.0 0.5 0.035 13.6 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KKK18524.1 - 0.017 15.0 0.1 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 KKK18524.1 - 0.017 14.4 0.1 0.056 12.8 0.0 1.9 1 0 0 1 1 1 0 Thymidylate kinase AAA_10 PF12846.2 KKK18524.1 - 0.049 13.0 0.0 0.083 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 KKK18524.1 - 0.1 12.0 1.0 0.44 10.0 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 KKK18524.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Rrp15p PF07890.7 KKK18525.1 - 9.4e-36 122.7 8.0 9.4e-36 122.7 5.5 2.3 2 1 0 2 2 2 1 Rrp15p Atrophin-1 PF03154.10 KKK18525.1 - 0.097 10.8 14.9 0.13 10.3 10.3 1.3 1 0 0 1 1 1 0 Atrophin-1 family CDC45 PF02724.9 KKK18525.1 - 1.3 6.9 15.1 2.1 6.3 10.4 1.4 1 0 0 1 1 1 0 CDC45-like protein SGT1 PF07093.6 KKK18525.1 - 6.8 4.9 20.0 8.9 4.5 13.8 1.1 1 0 0 1 1 1 0 SGT1 protein Hap4_Hap_bind PF10297.4 KKK18526.1 - 1.7e-08 33.9 6.0 1.7e-08 33.9 4.2 2.1 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KKK18526.1 - 1.1e-07 31.7 10.6 2.9e-06 27.1 7.4 2.7 1 1 1 2 2 2 1 bZIP transcription factor DUF2408 PF10303.4 KKK18526.1 - 0.0019 18.2 0.2 0.0034 17.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) FlaC_arch PF05377.6 KKK18526.1 - 0.072 12.9 1.2 0.15 11.9 0.8 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) dsrm PF00035.20 KKK18526.1 - 0.12 13.0 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif Phage_int_SAM_5 PF13102.1 KKK18526.1 - 0.15 12.0 0.3 0.26 11.2 0.2 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain Mnd1 PF03962.10 KKK18526.1 - 0.16 11.5 3.3 0.28 10.8 2.3 1.3 1 0 0 1 1 1 0 Mnd1 family bZIP_2 PF07716.10 KKK18526.1 - 0.61 9.9 17.6 0.078 12.8 6.6 2.9 2 1 1 3 3 3 0 Basic region leucine zipper Glyco_hydro_71 PF03659.9 KKK18527.1 - 2.1e-145 484.0 1.0 3e-145 483.5 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Peptidase_M18 PF02127.10 KKK18527.1 - 9.8e-119 396.6 0.0 7.3e-118 393.7 0.0 1.9 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Fer2 PF00111.22 KKK18528.1 - 6.6e-13 48.2 0.8 9.4e-13 47.7 0.6 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 KKK18529.1 - 6.2e-10 38.6 2.5 0.46 10.2 0.0 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein PBP1_TM PF14812.1 KKK18529.1 - 1.2 9.4 5.7 2.2 8.6 3.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.13 KKK18530.1 - 0.0001 21.3 0.4 0.00013 20.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.17 KKK18531.1 - 3.8e-80 263.5 4.1 1e-20 73.1 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK18531.1 - 2.1e-53 178.1 0.6 8.5e-14 51.2 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18531.1 - 3.5e-40 135.6 0.2 2.6e-09 36.7 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KKK18531.1 - 4e-31 106.4 2.4 9.3e-31 105.3 0.8 2.3 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KKK18531.1 - 1.3e-05 24.8 0.1 1.3 8.8 0.0 4.4 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 KKK18531.1 - 0.00038 20.6 4.0 0.74 10.0 0.0 3.9 5 0 0 5 5 5 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 KKK18531.1 - 0.017 14.8 5.5 13 5.6 0.0 3.7 3 0 0 3 3 3 0 Limkain b1 CSD PF00313.17 KKK18531.1 - 0.02 14.6 1.1 45 3.9 0.0 3.6 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KKK18531.1 - 0.041 13.3 1.5 7 6.2 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Fungal_trans PF04082.13 KKK18532.1 - 1.9e-10 40.0 0.1 3.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.18 KKK18534.1 - 5.9e-69 232.1 0.0 9.8e-69 231.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK18534.1 - 2.6e-14 52.8 0.0 7.2e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK18534.1 - 0.025 14.0 0.0 0.3 10.5 0.0 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase Plasmodium_Vir PF05795.6 KKK18536.1 - 0.43 9.7 4.6 0.6 9.2 3.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.4 KKK18536.1 - 1.1 7.4 10.4 1.2 7.2 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 KKK18536.1 - 3.2 5.7 14.9 4.2 5.3 10.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Fungal_trans_2 PF11951.3 KKK18537.1 - 8.5e-37 126.6 1.4 1.2e-36 126.2 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sterol_MT_C PF08498.5 KKK18538.1 - 2e-30 104.5 0.1 3.2e-30 103.8 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KKK18538.1 - 1e-21 77.2 0.0 2e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK18538.1 - 3.6e-18 65.6 0.0 5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK18538.1 - 1.5e-13 50.8 0.0 3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18538.1 - 1.8e-13 50.7 0.0 3.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KKK18538.1 - 7e-13 48.2 0.0 9.8e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KKK18538.1 - 2.4e-12 46.4 0.0 3.9e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KKK18538.1 - 2.2e-11 44.3 0.0 5.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK18538.1 - 4.1e-10 40.0 0.0 8.6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK18538.1 - 9.2e-10 38.5 0.0 3.2e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KKK18538.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KKK18538.1 - 6.6e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KKK18538.1 - 0.00021 20.5 0.0 0.00039 19.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 KKK18538.1 - 0.00028 20.4 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_29 PF03141.11 KKK18538.1 - 0.0018 16.7 0.0 0.0025 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 KKK18538.1 - 0.0018 17.3 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 KKK18538.1 - 0.0042 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 KKK18538.1 - 0.0048 17.7 0.1 0.025 15.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KKK18538.1 - 0.0071 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Sfi1 PF08457.5 KKK18538.1 - 0.016 13.6 0.5 0.021 13.2 0.3 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein Methyltransf_2 PF00891.13 KKK18538.1 - 0.032 13.4 0.9 0.064 12.4 0.1 1.9 1 1 0 2 2 2 0 O-methyltransferase TehB PF03848.9 KKK18538.1 - 0.04 13.0 0.0 0.084 12.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KKK18538.1 - 0.12 12.0 0.1 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Metal_resist PF13801.1 KKK18538.1 - 0.66 9.9 6.1 1.2 9.1 4.2 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Amidohydro_1 PF01979.15 KKK18539.1 - 1.3e-33 117.0 0.1 1.6e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KKK18539.1 - 0.00011 21.5 0.5 0.022 14.0 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KKK18539.1 - 0.0067 16.2 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KKK18539.1 - 0.34 10.8 6.7 1.3 8.9 4.7 2.0 1 1 0 1 1 1 0 Amidohydrolase GDC-P PF02347.11 KKK18540.1 - 1e-176 587.8 0.2 9.4e-163 541.8 0.0 2.8 3 1 0 3 3 3 2 Glycine cleavage system P-protein DegT_DnrJ_EryC1 PF01041.12 KKK18540.1 - 0.00088 18.4 1.1 0.026 13.5 0.0 2.4 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family SPOR PF05036.8 KKK18540.1 - 0.019 15.0 0.0 0.092 12.9 0.0 2.2 1 0 0 1 1 1 0 Sporulation related domain Med27 PF11571.3 KKK18541.1 - 2.4e-24 85.2 0.1 5.5e-24 84.1 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 Peptidase_S28 PF05577.7 KKK18542.1 - 3.3e-52 177.5 0.2 1.8e-51 175.1 0.1 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Aldedh PF00171.17 KKK18543.1 - 3.6e-128 427.8 0.0 4e-128 427.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KKK18543.1 - 7e-05 21.7 0.4 0.00051 18.8 0.3 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) adh_short PF00106.20 KKK18544.1 - 5.4e-28 97.9 2.9 7.7e-28 97.4 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK18544.1 - 1.4e-15 57.7 0.0 1.7e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK18544.1 - 4.1e-09 36.3 2.0 6e-09 35.8 1.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK18544.1 - 0.0012 18.3 0.1 0.0024 17.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK18544.1 - 0.0043 17.0 1.8 0.015 15.3 1.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KKK18544.1 - 0.0046 16.6 0.3 0.009 15.6 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KKK18544.1 - 0.038 13.0 0.1 0.11 11.5 0.1 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KKK18544.1 - 0.43 10.4 2.5 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.11 KKK18545.1 - 3.4e-33 114.8 35.1 3.4e-33 114.8 24.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3301 PF11743.3 KKK18545.1 - 0.089 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Gln-synt_C PF00120.19 KKK18546.1 - 1.4e-58 198.1 0.0 1.9e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Pkinase PF00069.20 KKK18547.1 - 4.6e-51 173.4 0.0 1.2e-50 172.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18547.1 - 1e-22 80.4 0.0 1.8e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK18547.1 - 0.00038 20.2 0.1 0.00092 19.0 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KKK18547.1 - 0.0021 17.4 1.0 0.012 14.9 0.7 2.0 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 KKK18547.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) eIF-3c_N PF05470.7 KKK18548.1 - 4.9e-155 516.9 27.5 4.9e-155 516.9 19.1 4.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KKK18548.1 - 1.3e-14 54.4 0.9 3.1e-13 49.9 0.1 3.1 2 1 0 2 2 2 1 PCI domain Pox_Ag35 PF03286.9 KKK18548.1 - 3.1 7.2 17.9 1.4 8.3 5.2 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Complex1_LYR PF05347.10 KKK18549.1 - 0.041 13.6 3.8 0.48 10.2 2.5 2.2 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK18549.1 - 0.12 12.6 2.1 1.5 9.1 1.4 2.4 2 1 0 2 2 2 0 Complex1_LYR-like RRM_1 PF00076.17 KKK18550.1 - 1.3e-09 37.5 0.0 2.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18550.1 - 1.3e-08 34.5 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK18550.1 - 1.9e-07 30.9 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK18550.1 - 0.001 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KKK18550.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Phosphoesterase PF04185.9 KKK18551.1 - 1.9e-30 106.3 3.0 3.5e-30 105.4 2.0 1.4 1 1 0 1 1 1 1 Phosphoesterase family DnaJ PF00226.26 KKK18552.1 - 7.5e-19 67.2 0.4 7.5e-19 67.2 0.3 2.5 2 0 0 2 2 2 1 DnaJ domain Glyco_hydro_43 PF04616.9 KKK18561.1 - 1.6e-06 27.4 0.0 1.8e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 EPL1 PF10513.4 KKK18562.1 - 2.1e-33 115.8 0.0 2.1e-33 115.8 0.0 2.2 2 1 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.1 KKK18562.1 - 3.7e-33 113.8 5.6 3.7e-33 113.8 3.9 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KKK18562.1 - 9.4e-28 96.2 2.0 9.4e-28 96.2 1.4 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KKK18562.1 - 1.7e-14 52.7 8.5 6.9e-14 50.8 1.7 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KKK18562.1 - 7.5e-10 38.3 19.3 5.6e-08 32.3 6.7 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 KKK18562.1 - 0.013 15.5 2.5 0.013 15.5 1.7 2.6 2 0 0 2 2 2 0 RING-like domain C1_1 PF00130.17 KKK18562.1 - 0.64 9.7 18.5 0.027 14.1 0.9 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 KKK18562.1 - 1.9 7.7 10.3 0.041 13.1 2.0 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 KKK18562.1 - 2.6 7.8 14.8 1.7 8.4 4.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RRM_1 PF00076.17 KKK18563.1 - 2.4e-21 75.1 0.0 3.3e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK18563.1 - 2.8e-17 62.4 0.0 3.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18563.1 - 1.7e-12 46.9 0.0 2.3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans_2 PF11951.3 KKK18565.1 - 3.5e-16 58.7 8.4 1.3e-15 56.9 5.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KKK18565.1 - 0.014 14.3 0.3 0.014 14.3 0.2 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK18566.1 - 5.2e-08 32.6 12.0 1.2e-07 31.4 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI-PLC-X PF00388.14 KKK18567.1 - 3.3e-58 195.2 0.0 5.3e-58 194.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KKK18567.1 - 3e-36 123.9 0.0 5.2e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Ribosomal_L37 PF08561.5 KKK18568.1 - 4.6e-30 103.0 6.4 5.4e-29 99.5 4.4 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 LELP1 PF15042.1 KKK18568.1 - 6.8 6.9 10.2 32 4.7 6.1 2.2 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 GST_N_3 PF13417.1 KKK18569.1 - 9.4e-09 35.3 0.1 2.6e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK18569.1 - 7.3e-06 25.7 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KKK18569.1 - 0.00064 19.6 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK18569.1 - 0.0021 17.9 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK18569.1 - 0.15 12.5 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Spherulin4 PF12138.3 KKK18570.1 - 7.7e-73 245.0 0.1 9.2e-73 244.7 0.1 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 OapA_N PF08525.6 KKK18570.1 - 0.82 9.5 7.5 1.4 8.7 5.2 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Epimerase PF01370.16 KKK18571.1 - 1.6e-34 119.3 0.0 3.7e-34 118.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KKK18571.1 - 2.8e-12 46.4 0.0 5.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 KKK18571.1 - 2.4e-08 33.2 0.0 7.9e-07 28.2 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KKK18571.1 - 3e-06 26.3 0.0 1.2e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KKK18571.1 - 1.6e-05 23.7 0.0 0.00017 20.4 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KKK18571.1 - 8e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KKK18571.1 - 0.00026 20.9 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KKK18571.1 - 0.00036 19.5 0.0 0.011 14.6 0.0 2.8 2 1 0 2 2 2 1 RmlD substrate binding domain PQQ PF01011.16 KKK18571.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat DUF1349 PF07081.6 KKK18581.1 - 1.2e-25 89.9 0.0 1.4e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.11 KKK18582.1 - 4.1e-23 81.6 39.4 5.7e-13 48.3 13.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK18582.1 - 2.2e-06 26.1 21.2 3.7e-06 25.4 14.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_C14 PF00656.17 KKK18585.1 - 1.2e-54 185.6 0.0 1.4e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Fungal_trans PF04082.13 KKK18596.1 - 5.1e-21 74.7 0.1 9.8e-21 73.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK18596.1 - 1.1e-08 34.8 15.4 0.00026 21.1 1.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK18596.1 - 1.2e-06 28.4 5.9 1.2e-06 28.4 4.1 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK18596.1 - 3.3e-05 23.9 16.2 0.049 13.9 2.2 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4072 PF13284.1 KKK18596.1 - 0.029 14.5 1.8 0.09 12.9 1.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) zf-C2H2_jaz PF12171.3 KKK18596.1 - 8.3 6.7 5.4 3.7 7.8 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Gram_pos_anchor PF00746.16 KKK18597.1 - 0.31 10.9 1.5 0.51 10.2 1.1 1.3 1 0 0 1 1 1 0 Gram positive anchor DUF4291 PF14124.1 KKK18598.1 - 1.3e-56 191.0 1.1 1.6e-56 190.8 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Methyltransf_23 PF13489.1 KKK18599.1 - 1.2e-24 86.8 0.0 2.2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK18599.1 - 2e-11 43.7 0.0 3e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18599.1 - 3.2e-10 40.5 0.0 3.5e-09 37.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18599.1 - 9.1e-07 29.2 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK18599.1 - 3.6e-05 24.1 0.0 0.00024 21.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KKK18599.1 - 0.00087 18.3 0.0 0.018 14.0 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 KKK18599.1 - 0.0018 17.4 0.0 1.2 8.2 0.0 2.7 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KKK18599.1 - 0.0021 18.0 0.0 0.042 13.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18599.1 - 0.0049 17.2 0.0 0.026 14.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 KKK18599.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TRM PF02005.11 KKK18599.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 KKK18599.1 - 0.16 11.3 0.0 0.46 9.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 KKK18599.1 - 0.17 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-DHHC PF01529.15 KKK18600.1 - 7.6e-06 25.4 3.6 1.1e-05 24.9 2.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase MpPF26 PF07666.6 KKK18600.1 - 0.31 10.9 2.9 0.48 10.3 2.0 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 COX4_pro_2 PF07835.7 KKK18600.1 - 0.92 9.5 6.2 1.6 8.7 4.3 1.4 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Myosin_head PF00063.16 KKK18602.1 - 4e-254 844.8 0.3 1.3e-253 843.1 0.2 2.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KKK18602.1 - 1.3e-22 79.4 302.4 2.3e-19 68.6 93.7 6.0 1 1 3 4 4 4 2 Myosin tail Myosin_N PF02736.14 KKK18602.1 - 0.00025 20.6 0.0 0.00074 19.1 0.0 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KKK18602.1 - 0.084 12.6 0.0 0.29 10.9 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain zf-C3H1 PF10650.4 KKK18603.1 - 1.2e-11 43.8 2.7 2e-11 43.1 1.9 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain APG6 PF04111.7 KKK18603.1 - 3.6 6.5 12.9 0.14 11.1 1.7 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 F-box-like PF12937.2 KKK18604.1 - 1.3e-07 31.1 0.1 3e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like POTRA_1 PF08478.5 KKK18604.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, FtsQ-type F-box PF00646.28 KKK18604.1 - 0.036 13.7 0.0 0.036 13.7 0.0 3.1 4 0 0 4 4 4 0 F-box domain tRNA-synt_2 PF00152.15 KKK18605.1 - 1.1e-72 244.7 0.4 1.5e-72 244.1 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Hydrolase_6 PF13344.1 KKK18605.1 - 4e-24 84.4 0.0 1.1e-23 83.0 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK18605.1 - 7.3e-16 57.6 0.0 7.9e-15 54.3 0.0 2.7 3 0 0 3 3 3 1 HAD-hyrolase-like tRNA_anti-codon PF01336.20 KKK18605.1 - 2.3e-05 24.1 0.1 4.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HAD_2 PF13419.1 KKK18605.1 - 2.6e-05 24.5 0.2 0.11 12.6 0.0 4.7 4 1 1 5 5 5 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK18605.1 - 0.00041 20.8 0.2 0.37 11.1 0.0 3.5 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase adh_short PF00106.20 KKK18606.1 - 1.7e-58 197.2 6.4 4.5e-29 101.5 1.4 2.5 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 KKK18606.1 - 5.9e-32 109.6 0.0 1.1e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 KKK18606.1 - 4.9e-28 98.0 1.1 6.5e-13 48.7 0.3 2.4 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 KKK18606.1 - 4e-06 25.9 1.3 0.00017 20.7 0.2 2.7 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KKK18606.1 - 0.0014 18.0 0.9 1.6 8.1 0.1 2.7 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family Kinetocho_Slk19 PF12709.2 KKK18618.1 - 8.6e-25 86.6 30.2 2.6e-23 81.9 5.9 4.4 4 0 0 4 4 4 2 Central kinetochore-associated AAA_13 PF13166.1 KKK18618.1 - 0.11 10.9 23.2 0.011 14.2 1.9 2.3 2 0 0 2 2 2 0 AAA domain Fib_alpha PF08702.5 KKK18618.1 - 2.4 8.2 14.9 30 4.7 5.7 3.4 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 KKK18618.1 - 4.5 7.1 32.8 7.7 6.4 0.5 4.4 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding ERM PF00769.14 KKK18618.1 - 5.4 6.4 49.7 1.3 8.5 17.1 2.9 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DIT1_PvcA PF05141.7 KKK18618.1 - 8.7 5.5 10.5 14 4.9 3.8 2.2 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein MFS_1 PF07690.11 KKK18620.1 - 1.5e-30 106.0 32.5 5e-28 97.8 14.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK18620.1 - 2.7e-12 45.9 3.6 2.7e-12 45.9 2.5 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KKK18620.1 - 7.4 4.5 13.5 0.49 8.4 1.3 2.9 2 2 1 3 3 3 0 Transmembrane secretion effector Copper-fist PF00649.13 KKK18634.1 - 5.3e-22 76.7 2.8 5.3e-22 76.7 1.9 2.9 2 1 1 3 3 3 1 Copper fist DNA binding domain Apc13p PF05839.6 KKK18636.1 - 5e-18 64.8 0.0 1.2e-17 63.5 0.0 1.7 2 0 0 2 2 2 1 Apc13p protein CBS PF00571.23 KKK18637.1 - 1.2e-22 79.4 4.2 1e-11 44.4 0.1 4.0 4 0 0 4 4 4 3 CBS domain CRAL_TRIO PF00650.15 KKK18638.1 - 1.1e-32 112.6 0.0 2e-32 111.8 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK18638.1 - 5.4e-12 45.6 0.0 1.3e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KKK18638.1 - 0.0001 22.2 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Suc_Fer-like PF06999.7 KKK18639.1 - 0.08 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Aminotran_1_2 PF00155.16 KKK18640.1 - 1.7e-24 86.4 0.0 4.4e-24 85.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK18640.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF4129 PF13559.1 KKK18641.1 - 8.4e-05 22.4 0.1 0.00026 20.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Acyl_transf_3 PF01757.17 KKK18641.1 - 0.018 13.8 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase family Ribosomal_60s PF00428.14 KKK18641.1 - 0.18 12.2 4.1 4.1 7.8 0.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans PF04082.13 KKK18642.1 - 1.6e-23 82.9 2.8 2.1e-22 79.2 0.0 2.8 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK18642.1 - 0.0036 17.1 4.9 0.0061 16.4 3.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavin_Reduct PF01613.13 KKK18643.1 - 5.3e-18 65.3 0.0 7.5e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 KKK18643.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF447) Fungal_trans_2 PF11951.3 KKK18651.1 - 4e-07 28.9 1.0 7.3e-07 28.1 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK18651.1 - 2.5e-06 27.2 9.2 5.3e-06 26.2 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_2 PF13646.1 KKK18651.1 - 0.025 14.8 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats MFS_1 PF07690.11 KKK18652.1 - 4.4e-14 51.9 9.7 1.2e-13 50.5 6.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily YflT PF11181.3 KKK18652.1 - 0.11 12.6 0.4 0.2 11.8 0.3 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT TRP PF06011.7 KKK18654.1 - 2.9e-95 319.4 23.4 1.3e-94 317.3 16.2 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KKK18654.1 - 6.4e-29 100.8 0.1 9.6e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 ML-like domain FYVE PF01363.16 KKK18655.1 - 3.7e-21 74.8 1.0 3.7e-21 74.8 0.7 3.5 4 0 0 4 4 4 1 FYVE zinc finger Fungal_trans PF04082.13 KKK18655.1 - 1.9e-05 23.6 0.0 4.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK18655.1 - 5e-05 23.1 9.8 5e-05 23.1 6.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asn_synthase PF00733.16 KKK18668.1 - 1.9e-68 230.7 0.0 2.6e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KKK18668.1 - 4.4e-35 120.1 0.0 7.3e-35 119.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KKK18668.1 - 8e-26 90.5 0.0 1.4e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KKK18668.1 - 4.7e-10 39.0 0.0 9e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KKK18668.1 - 0.00048 19.1 0.0 0.00097 18.1 0.0 1.6 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KKK18668.1 - 0.018 13.7 0.0 1.9 7.0 0.0 2.8 1 1 2 3 3 3 0 Glutamine amidotransferases class-II Curto_V2 PF07325.6 KKK18668.1 - 0.045 13.4 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein DUF2939 PF11159.3 KKK18668.1 - 0.058 13.5 0.0 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Porin_3 PF01459.17 KKK18669.1 - 7.2e-68 228.8 0.0 1.3e-67 228.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic porin KdpC PF02669.10 KKK18669.1 - 0.029 14.0 0.6 0.064 12.9 0.3 1.6 2 0 0 2 2 2 0 K+-transporting ATPase, c chain DnaJ PF00226.26 KKK18670.1 - 0.0043 16.7 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Serglycin PF04360.7 KKK18670.1 - 0.077 12.7 3.7 0.11 12.2 2.2 1.6 1 1 0 1 1 1 0 Serglycin RICTOR_N PF14664.1 KKK18671.1 - 7.6e-139 462.4 1.0 1.9e-138 461.1 0.6 1.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KKK18671.1 - 5.9e-89 296.9 0.4 4.7e-87 290.7 0.1 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KKK18671.1 - 1.9e-44 150.3 0.0 1.8e-42 143.9 0.0 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KKK18671.1 - 1.9e-24 85.4 4.1 1.4e-23 82.5 0.1 3.9 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KKK18671.1 - 3.2e-14 52.4 4.1 7.2e-14 51.2 2.8 1.7 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 KKK18671.1 - 0.0034 17.3 5.6 0.0092 15.9 3.9 1.7 1 0 0 1 1 1 1 Up-regulated During Septation PsiA PF06952.6 KKK18671.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 PsiA protein Arm PF00514.18 KKK18671.1 - 0.58 10.0 4.3 16 5.5 0.1 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cytochrom_B561 PF03188.11 KKK18672.1 - 2.7e-05 24.0 5.2 2.7e-05 24.0 3.6 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 p450 PF00067.17 KKK18673.1 - 1.3e-63 215.2 0.0 2.5e-63 214.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Kinetochor_Ybp2 PF08568.5 KKK18674.1 - 7.5e-161 536.5 0.0 9.9e-161 536.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-DHHC PF01529.15 KKK18676.1 - 1.7e-40 138.2 0.2 3.2e-40 137.3 0.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase UQ_con PF00179.21 KKK18676.1 - 8.7e-22 77.0 0.0 1.8e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DZR PF12773.2 KKK18676.1 - 0.037 13.8 6.6 0.09 12.6 4.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon Vma12 PF11712.3 KKK18676.1 - 0.42 10.3 4.5 6.7 6.4 0.1 3.1 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Rhomboid PF01694.17 KKK18677.1 - 5.1e-34 117.3 10.8 5.1e-34 117.3 7.5 2.0 3 0 0 3 3 3 1 Rhomboid family DUF4203 PF13886.1 KKK18677.1 - 0.0074 15.7 2.9 0.0074 15.7 2.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4203) Wzy_C PF04932.10 KKK18677.1 - 0.44 10.3 5.0 3.9 7.2 0.1 3.1 3 0 0 3 3 3 0 O-Antigen ligase QueT PF06177.6 KKK18677.1 - 1.2 9.0 6.9 2.4 8.1 0.1 2.6 2 0 0 2 2 2 0 QueT transporter DUF3317 PF11779.3 KKK18678.1 - 1.6e-20 72.2 2.0 3.8e-20 71.0 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) PgaD PF13994.1 KKK18678.1 - 0.0095 15.4 0.6 0.014 14.8 0.4 1.3 1 0 0 1 1 1 1 PgaD-like protein Cytochrome_CBB3 PF13442.1 KKK18680.1 - 0.12 12.5 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III WH1 PF00568.18 KKK18681.1 - 1.3e-29 102.1 0.0 2e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 WH1 domain MSA-2c PF12238.3 KKK18681.1 - 4.4 6.9 6.9 0.48 10.0 1.7 1.6 2 0 0 2 2 2 0 Merozoite surface antigen 2c eIF-1a PF01176.14 KKK18682.1 - 1.2e-28 98.2 0.1 1.7e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.10 KKK18683.1 - 1.3e-19 70.4 0.0 3.9e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.1 KKK18683.1 - 0.00037 20.5 0.0 0.00096 19.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain PTCB-BRCT PF12738.2 KKK18684.1 - 3.4e-11 42.8 0.0 6.3e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KKK18684.1 - 8.8e-08 32.1 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF605 PF04652.11 KKK18684.1 - 0.00098 18.6 14.5 0.0012 18.2 10.1 1.1 1 0 0 1 1 1 1 Vta1 like fn3 PF00041.16 KKK18684.1 - 0.0013 18.8 0.6 0.0036 17.3 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain DUF3006 PF11213.3 KKK18684.1 - 0.003 17.2 0.0 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) Na_trans_assoc PF06512.8 KKK18684.1 - 0.14 12.1 4.0 0.21 11.5 2.8 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Tetraspannin PF00335.15 KKK18718.1 - 0.0014 17.9 0.1 0.0018 17.6 0.1 1.2 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.18 KKK18718.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Membrane-associating domain Reprolysin_4 PF13583.1 KKK18719.1 - 0.047 13.2 0.2 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like MFS_1 PF07690.11 KKK18720.1 - 2.8e-05 23.0 5.0 3.8e-05 22.5 3.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Aminotran_3 PF00202.16 KKK18721.1 - 1.7e-37 129.0 0.9 6.2e-35 120.6 0.6 2.8 1 1 0 1 1 1 1 Aminotransferase class-III FAD_binding_4 PF01565.18 KKK18722.1 - 8e-31 106.3 4.8 1.4e-30 105.5 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK18722.1 - 9.7e-09 35.0 0.3 2.4e-08 33.7 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like AAA_16 PF13191.1 KKK18723.1 - 3.7e-09 36.8 3.3 9.8e-09 35.4 0.1 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KKK18723.1 - 1.1e-08 35.2 0.5 1e-07 32.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain TPR_10 PF13374.1 KKK18723.1 - 2.7e-08 33.4 0.6 0.15 11.9 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat NACHT PF05729.7 KKK18723.1 - 7.9e-08 32.1 0.8 4.1e-07 29.8 0.0 2.7 2 1 0 2 2 2 1 NACHT domain TPR_2 PF07719.12 KKK18723.1 - 0.00054 19.6 1.4 54 4.0 0.1 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA PF00004.24 KKK18723.1 - 0.0019 18.4 0.0 0.022 14.9 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TPR_7 PF13176.1 KKK18723.1 - 0.0027 17.3 0.3 1.7 8.5 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_19 PF13245.1 KKK18723.1 - 0.006 16.3 0.0 0.032 13.9 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain TPR_12 PF13424.1 KKK18723.1 - 0.0063 16.4 23.2 7.2 6.6 0.1 8.9 10 0 0 10 10 10 1 Tetratricopeptide repeat AAA_17 PF13207.1 KKK18723.1 - 0.11 13.3 0.0 0.43 11.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain SET PF00856.23 KKK18724.1 - 9.8e-10 38.9 0.1 7.7e-08 32.8 0.1 2.2 2 0 0 2 2 2 2 SET domain REC114-like PF15165.1 KKK18724.1 - 0.036 13.7 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Methyltransf_31 PF13847.1 KKK18725.1 - 1.5e-15 57.1 0.0 2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18725.1 - 8.7e-15 55.2 0.0 1.4e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK18725.1 - 4.1e-13 49.3 0.0 5.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18725.1 - 2.5e-12 47.1 0.0 4.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18725.1 - 5.2e-11 42.8 0.0 1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK18725.1 - 1.1e-09 38.6 0.0 1.7e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK18725.1 - 7.6e-08 32.4 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK18725.1 - 2.9e-06 26.7 0.0 4.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KKK18725.1 - 1.9e-05 23.9 0.0 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase TehB PF03848.9 KKK18725.1 - 8.3e-05 21.8 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.14 KKK18725.1 - 0.00014 21.9 0.0 0.00019 21.4 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.13 KKK18725.1 - 0.00039 19.7 0.0 0.032 13.5 0.0 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.6 KKK18725.1 - 0.0018 17.6 0.0 0.0032 16.8 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 KKK18725.1 - 0.0025 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KKK18725.1 - 0.0094 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 KKK18725.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 KKK18725.1 - 0.017 14.2 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 KKK18725.1 - 0.018 14.0 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 KKK18725.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GMC_oxred_C PF05199.8 KKK18726.1 - 3.7e-39 134.3 0.0 4.9e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KKK18726.1 - 1.5e-10 40.7 0.1 2e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase ELFV_dehydrog_N PF02812.13 KKK18726.1 - 0.15 11.6 0.2 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CN_hydrolase PF00795.17 KKK18727.1 - 3.4e-26 91.7 0.0 4.8e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GST_N_3 PF13417.1 KKK18728.1 - 8e-07 29.1 0.0 4.2e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK18728.1 - 0.00086 19.2 0.0 0.0022 17.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK18728.1 - 0.051 13.4 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF455 PF04305.9 KKK18729.1 - 4e-103 344.0 0.0 5.1e-103 343.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 KKK18729.1 - 2.6e-06 26.9 0.0 5.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KKK18729.1 - 0.0015 18.1 0.0 0.0061 16.2 0.0 2.1 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain FAD_binding_3 PF01494.14 KKK18730.1 - 5.8e-24 84.7 0.0 1.3e-22 80.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK18730.1 - 2.2e-07 30.1 0.0 0.0017 17.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK18730.1 - 0.00017 21.9 1.5 0.0019 18.5 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK18730.1 - 0.00023 20.1 0.1 0.0045 15.9 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KKK18730.1 - 0.00028 20.8 0.1 0.00074 19.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KKK18730.1 - 0.0007 18.7 0.0 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase SE PF08491.5 KKK18730.1 - 0.00088 18.1 0.0 0.003 16.4 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 KKK18730.1 - 0.11 11.0 0.3 3.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KKK18730.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cnd3 PF12719.2 KKK18737.1 - 6.4e-90 301.1 0.1 9.6e-89 297.2 0.0 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KKK18737.1 - 8.2e-11 42.0 1.6 8e-07 29.2 0.1 4.3 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KKK18737.1 - 1.5e-07 31.7 2.7 0.0034 17.8 0.1 4.7 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KKK18737.1 - 0.00011 22.0 4.9 0.035 14.1 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat PyrBI_leader PF08052.6 KKK18737.1 - 0.11 12.2 0.2 0.25 11.1 0.2 1.5 1 0 0 1 1 1 0 PyrBI operon leader peptide Cohesin_HEAT PF12765.2 KKK18737.1 - 0.13 12.2 1.5 0.9 9.5 0.1 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion zf-RanBP PF00641.13 KKK18738.1 - 1e-20 72.5 9.1 6.3e-11 41.1 1.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KKK18738.1 - 2.3e-08 33.5 0.0 5.9e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KKK18738.1 - 4.7e-07 30.2 0.0 7.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 KKK18738.1 - 1.7e-06 27.8 0.0 8e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 KKK18738.1 - 0.54 10.1 8.3 0.81 9.5 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon MFS_1 PF07690.11 KKK18739.1 - 9e-53 179.2 34.8 3.5e-49 167.4 13.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KKK18739.1 - 0.00056 18.1 14.6 0.00062 18.0 2.2 2.4 2 0 0 2 2 2 2 Transmembrane secretion effector DIOX_N PF14226.1 KKK18740.1 - 3.9e-15 56.3 0.0 7.3e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK18740.1 - 6.6e-15 55.2 0.2 1.4e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 KKK18741.1 - 8.8e-62 208.8 0.0 1.2e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KKK18741.1 - 1.4e-26 93.0 0.0 3.5e-25 88.4 0.0 2.3 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.20 KKK18741.1 - 1.3e-07 31.7 0.0 2.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK18741.1 - 0.00015 22.6 0.0 0.00055 20.8 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3283 PF11686.3 KKK18741.1 - 0.19 11.5 0.0 0.55 10.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) PS_Dcarbxylase PF02666.10 KKK18742.1 - 6.1e-35 120.3 0.0 8.4e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 KKK18742.1 - 4.3e-31 107.4 0.0 7.7e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.1 KKK18742.1 - 0.0013 18.3 0.0 0.98 9.1 0.0 2.9 3 0 0 3 3 3 2 RnfC Barrel sandwich hybrid domain Lipase3_N PF03893.11 KKK18743.1 - 4.5e-07 29.5 1.2 1.6e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 Lipase 3 N-terminal region HECA PF15353.1 KKK18743.1 - 0.03 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Headcase protein family homologue DUF3431 PF11913.3 KKK18744.1 - 1.3e-90 302.7 0.3 1.9e-90 302.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Peptidase_M16_C PF05193.16 KKK18745.1 - 5.3e-32 110.9 0.0 9e-23 80.8 0.0 3.3 3 1 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KKK18745.1 - 1.4e-31 109.2 4.1 1.4e-22 80.1 0.3 3.5 3 1 1 4 4 4 2 Insulinase (Peptidase family M16) NUDIX_2 PF13869.1 KKK18746.1 - 1.5e-73 246.1 0.1 4.6e-72 241.3 0.1 2.0 1 1 0 1 1 1 1 Nucleotide hydrolase Hist_deacetyl PF00850.14 KKK18747.1 - 3e-95 319.0 0.1 5.8e-95 318.1 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KKK18747.1 - 1.2e-55 187.6 0.1 5.1e-55 185.6 0.0 1.9 2 0 0 2 2 2 1 Arb2 domain Bys1 PF04681.7 KKK18748.1 - 2.6e-11 43.4 0.4 3.1e-11 43.2 0.3 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein zf-CHCC PF10276.4 KKK18749.1 - 1.7e-15 56.5 1.4 2.6e-15 55.9 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 KKK18749.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb MPP6 PF10175.4 KKK18750.1 - 0.37 11.1 0.1 0.37 11.1 0.1 2.1 2 1 0 2 2 2 0 M-phase phosphoprotein 6 F-box-like PF12937.2 KKK18751.1 - 1.6e-08 34.1 0.1 4.5e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK18751.1 - 0.12 12.0 0.6 3.3 7.4 0.1 2.7 2 0 0 2 2 2 0 F-box domain UPF0047 PF01894.12 KKK18752.1 - 2.3e-40 137.0 0.0 2.6e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Exo_endo_phos PF03372.18 KKK18753.1 - 1.5e-22 80.7 1.0 2e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PQQ_2 PF13360.1 KKK18753.1 - 0.015 14.7 0.0 0.053 12.9 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain WD40 PF00400.27 KKK18753.1 - 1.3 9.0 9.5 2.4 8.1 1.8 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat BTB PF00651.26 KKK18754.1 - 9.9e-07 28.7 1.5 2.1e-06 27.6 0.3 1.9 2 0 0 2 2 2 1 BTB/POZ domain Proteasome PF00227.21 KKK18755.1 - 2.5e-55 186.7 0.0 3.5e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KKK18755.1 - 6.4e-14 50.9 0.1 6.4e-14 50.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 KKK18755.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.7 KKK18756.1 - 2.8e-11 43.3 16.7 1.7e-09 37.6 8.0 2.1 2 0 0 2 2 2 2 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 KKK18756.1 - 0.038 13.8 10.6 0.77 9.6 0.4 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Cytochrome_C7 PF14522.1 KKK18756.1 - 0.042 13.4 9.3 0.069 12.7 6.4 1.3 1 0 0 1 1 1 0 Cytochrome c7 C1_4 PF07975.7 KKK18756.1 - 0.06 13.3 11.9 1.2 9.2 4.1 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain zf-FPG_IleRS PF06827.9 KKK18756.1 - 0.086 12.5 2.2 0.24 11.0 1.5 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS RNA_POL_M_15KD PF02150.11 KKK18756.1 - 0.18 11.5 5.0 14 5.4 0.0 3.3 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit DUF3797 PF12677.2 KKK18756.1 - 0.22 11.1 4.3 3.4 7.3 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) Zn-ribbon_8 PF09723.5 KKK18756.1 - 0.26 11.2 12.8 1.8 8.5 5.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 KKK18756.1 - 0.46 10.1 9.9 3.9 7.1 0.9 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_3 PF14369.1 KKK18756.1 - 0.7 9.9 10.5 1.5 8.8 4.8 2.7 1 1 1 2 2 2 0 zinc-finger zinc_ribbon_4 PF13717.1 KKK18756.1 - 0.71 9.6 10.1 4 7.1 1.0 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Evr1_Alr PF04777.8 KKK18756.1 - 4.3 7.3 10.2 1.1e+02 2.8 7.1 2.8 1 1 0 1 1 1 0 Erv1 / Alr family HypA PF01155.14 KKK18756.1 - 5 6.8 10.9 0.35 10.5 2.6 2.1 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family Ribosomal_L37ae PF01780.14 KKK18756.1 - 5.6 6.9 6.1 3.5 7.5 2.3 1.8 1 1 1 2 2 2 0 Ribosomal L37ae protein family eIF-1a PF01176.14 KKK18757.1 - 0.02 14.2 0.2 0.033 13.6 0.2 1.3 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 CoaE PF01121.15 KKK18758.1 - 2.8e-40 137.6 0.0 5e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KKK18758.1 - 0.0022 18.8 0.3 0.0068 17.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KKK18758.1 - 0.037 14.3 0.3 0.3 11.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain ATG13 PF10033.4 KKK18763.1 - 1.5e-75 253.6 0.0 2.3e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 HEAT_2 PF13646.1 KKK18789.1 - 3e-31 107.5 2.1 2e-14 53.6 0.0 3.4 3 1 1 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 KKK18789.1 - 6.4e-20 69.5 0.1 0.023 15.1 0.0 6.8 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KKK18789.1 - 1.3e-10 41.3 4.1 0.0092 16.4 0.1 5.3 5 2 1 6 6 6 3 HEAT-like repeat HEAT PF02985.17 KKK18789.1 - 6.1e-08 32.1 2.0 4.7 7.5 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat Cohesin_HEAT PF12765.2 KKK18789.1 - 0.017 15.0 0.3 0.69 9.9 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion RuvA_C PF07499.8 KKK18789.1 - 0.019 15.0 0.4 3.3 7.9 0.0 3.0 2 0 0 2 2 2 0 RuvA, C-terminal domain Pkinase PF00069.20 KKK18790.1 - 1.2e-06 27.9 0.0 3.2e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Nipped-B_C PF12830.2 KKK18791.1 - 6.4e-50 169.3 0.4 6.4e-50 169.3 0.3 3.6 4 1 1 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KKK18791.1 - 8.5e-13 47.9 3.0 6.9e-12 45.0 1.0 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 KKK18791.1 - 1.7e-05 23.3 1.1 0.00042 18.7 0.4 3.0 2 1 0 2 2 2 1 Adaptin N terminal region Xpo1 PF08389.7 KKK18791.1 - 0.009 15.9 0.1 1.9 8.3 0.0 3.7 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 KKK18791.1 - 0.014 15.4 7.5 0.72 10.0 0.1 5.6 6 0 0 6 6 6 0 HEAT repeat Pyr_redox_2 PF07992.9 KKK18792.1 - 2.2e-16 60.3 0.0 4.3e-16 59.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK18792.1 - 9e-12 45.2 0.0 2e-10 40.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 KKK18792.1 - 5.4e-07 28.4 0.1 1.5e-06 27.0 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KKK18792.1 - 3.6e-06 26.0 0.3 8.9e-06 24.8 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KKK18792.1 - 7.1e-06 25.4 0.3 2.2e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KKK18792.1 - 1.9e-05 24.6 1.1 4e-05 23.6 0.0 2.0 3 0 0 3 3 3 1 EF-hand domain pair Methyltrn_RNA_4 PF09936.4 KKK18792.1 - 0.14 11.6 0.0 0.71 9.3 0.0 2.2 3 0 0 3 3 3 0 SAM-dependent RNA methyltransferase TFIIS_C PF01096.13 KKK18793.1 - 3.8e-15 55.2 9.5 1.4e-14 53.4 1.8 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KKK18793.1 - 0.0015 18.1 0.2 0.0015 18.1 0.1 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 KKK18793.1 - 0.0074 16.0 5.6 0.48 10.2 3.9 2.4 1 1 0 1 1 1 1 Double zinc ribbon Lar_restr_allev PF14354.1 KKK18793.1 - 0.016 15.5 5.7 2.1 8.7 0.3 3.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 KKK18793.1 - 0.13 12.2 4.4 5.8 6.9 0.1 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 KKK18793.1 - 0.14 11.6 7.5 4 7.0 0.6 3.5 3 1 1 4 4 4 0 zinc-ribbon domain zf-ISL3 PF14690.1 KKK18793.1 - 0.17 11.9 1.0 23 5.1 0.0 3.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TF_Zn_Ribbon PF08271.7 KKK18793.1 - 0.23 10.8 9.0 0.97 8.8 0.1 3.5 4 0 0 4 4 4 0 TFIIB zinc-binding NMD3 PF04981.8 KKK18793.1 - 0.37 9.8 3.7 2.1 7.3 2.6 2.2 1 1 0 1 1 1 0 NMD3 family zf-C3HC4_3 PF13920.1 KKK18793.1 - 0.44 10.2 6.3 13 5.5 0.1 3.4 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 KKK18793.1 - 0.47 10.1 6.5 0.39 10.3 0.2 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain PhnA_Zn_Ribbon PF08274.7 KKK18793.1 - 0.66 9.8 3.2 17 5.2 0.0 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-B_box PF00643.19 KKK18793.1 - 1.5 8.7 5.5 25 4.8 0.1 3.1 3 0 0 3 3 3 0 B-box zinc finger Zn_Tnp_IS1595 PF12760.2 KKK18793.1 - 1.8 8.4 4.9 1.7 8.5 0.1 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 KKK18793.1 - 1.9 7.8 12.9 2.7 7.3 0.1 3.4 3 1 1 4 4 4 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KKK18793.1 - 3 7.6 8.5 2.3 7.9 2.2 2.9 2 1 0 2 2 2 0 Nudix N-terminal Glyco_transf_34 PF05637.7 KKK18795.1 - 1.1e-17 64.3 0.0 3.1e-10 39.9 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KKK18795.1 - 0.0011 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Pkinase PF00069.20 KKK18796.1 - 2.2e-22 79.4 0.0 6.5e-22 77.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18796.1 - 5.8e-21 74.7 0.0 1.6e-20 73.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KKK18796.1 - 0.0016 17.8 0.0 0.031 13.6 0.0 2.0 2 0 0 2 2 2 1 RIO1 family PLD_C PF12357.3 KKK18796.1 - 0.0029 17.1 0.0 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 Phospholipase D C terminal Kdo PF06293.9 KKK18796.1 - 0.044 12.8 0.2 0.071 12.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK18796.1 - 0.1 12.2 1.0 0.26 11.0 0.4 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK18796.1 - 0.19 11.3 0.4 0.6 9.6 0.2 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase Dak1 PF02733.12 KKK18797.1 - 2.8e-104 348.2 0.0 3.9e-104 347.7 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KKK18797.1 - 5.8e-39 133.5 0.9 9.2e-39 132.9 0.6 1.3 1 0 0 1 1 1 1 DAK2 domain Abhydrolase_3 PF07859.8 KKK18798.1 - 8.1e-50 169.3 0.0 1e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK18798.1 - 4.1e-08 32.4 0.0 9.1e-08 31.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KKK18798.1 - 0.00035 20.3 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KKK18798.1 - 0.097 11.2 0.0 0.18 10.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Esterase_phd PF10503.4 KKK18798.1 - 0.12 11.6 0.2 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase AA_permease_2 PF13520.1 KKK18799.1 - 1.8e-24 86.0 43.0 2.1e-24 85.8 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK18799.1 - 7.1e-11 41.1 33.8 9e-11 40.7 23.4 1.1 1 0 0 1 1 1 1 Amino acid permease Cupin_2 PF07883.6 KKK18800.1 - 0.001 18.5 0.3 0.071 12.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain SPOC PF07744.8 KKK18800.1 - 0.0014 19.0 0.0 0.0022 18.4 0.0 1.3 1 0 0 1 1 1 1 SPOC domain MannoseP_isomer PF01050.13 KKK18800.1 - 0.035 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase COesterase PF00135.23 KKK18801.1 - 1.4e-43 149.4 0.2 1e-40 139.9 0.0 2.2 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK18801.1 - 1.4e-09 37.8 0.2 4.3e-09 36.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold ADH_N PF08240.7 KKK18801.1 - 5.1e-06 26.2 0.0 1.5e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK18801.1 - 0.0023 17.5 0.0 0.01 15.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_5 PF12695.2 KKK18801.1 - 0.027 14.2 0.0 0.084 12.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family zf-PARP PF00645.13 KKK18802.1 - 3.3e-24 84.9 0.0 5.8e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Pyr_redox_3 PF13738.1 KKK18803.1 - 3e-21 76.4 0.0 6.9e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK18803.1 - 4.3e-10 38.4 0.0 5e-09 34.9 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK18803.1 - 2e-07 30.9 0.0 5.8e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK18803.1 - 0.00014 21.6 1.7 0.00031 20.5 0.0 2.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KKK18803.1 - 0.00033 19.6 0.0 0.0024 16.8 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 KKK18803.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1168 PF06658.7 KKK18804.1 - 1.6e-43 147.6 12.1 2.3e-43 147.1 8.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Hid1 PF12722.2 KKK18804.1 - 0.92 7.1 4.0 0.87 7.1 2.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3513 PF12026.3 KKK18804.1 - 2.1 7.8 5.2 3.2 7.2 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Peptidase_S49_N PF08496.5 KKK18804.1 - 4.6 7.0 5.4 6.9 6.4 3.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Menin PF05053.8 KKK18804.1 - 6.1 4.8 8.6 7.7 4.5 6.0 1.1 1 0 0 1 1 1 0 Menin Cpn60_TCP1 PF00118.19 KKK18805.1 - 1.8e-164 547.9 0.1 2.1e-164 547.7 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UQ_con PF00179.21 KKK18806.1 - 1.4e-22 79.6 0.0 2.4e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3435 PF11917.3 KKK18808.1 - 9e-12 44.4 0.0 1.2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) bZIP_1 PF00170.16 KKK18809.1 - 5.6e-10 39.0 16.4 3.6e-09 36.4 10.1 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 KKK18809.1 - 2.4e-06 27.2 17.4 0.00013 21.6 8.1 2.3 1 1 1 2 2 2 2 Basic region leucine zipper Jnk-SapK_ap_N PF09744.4 KKK18809.1 - 0.00012 22.0 10.3 0.00019 21.4 7.1 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF972 PF06156.8 KKK18809.1 - 0.00026 21.2 1.4 0.00026 21.2 1.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF972) Phlebovirus_NSM PF07246.6 KKK18809.1 - 0.00041 19.6 3.2 0.00055 19.1 2.2 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M PTRF_SDPR PF15237.1 KKK18809.1 - 0.03 13.7 7.5 0.022 14.1 3.9 1.6 1 1 1 2 2 2 0 PTRF/SDPR family Microtub_assoc PF07989.6 KKK18809.1 - 0.078 12.8 0.2 0.078 12.8 0.2 2.2 1 1 1 2 2 2 0 Microtubule associated TMF_DNA_bd PF12329.3 KKK18809.1 - 0.093 12.5 3.5 0.13 12.0 1.5 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_Maf PF03131.12 KKK18809.1 - 0.23 11.7 15.8 0.1 12.8 9.4 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 KKK18809.1 - 0.34 10.4 7.1 0.5 9.9 4.9 1.3 1 0 0 1 1 1 0 IncA protein OmpH PF03938.9 KKK18809.1 - 0.37 10.7 6.7 0.49 10.3 4.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1640 PF07798.6 KKK18809.1 - 0.65 10.0 6.5 0.86 9.6 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Spore_coat_CotO PF14153.1 KKK18809.1 - 0.87 8.9 7.3 1.1 8.6 5.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DivIC PF04977.10 KKK18809.1 - 1.2 8.6 11.8 0.37 10.3 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF904 PF06005.7 KKK18809.1 - 1.6 9.1 11.7 0.11 12.8 4.2 1.9 2 1 1 3 3 2 0 Protein of unknown function (DUF904) Abhydrolase_6 PF12697.2 KKK18810.1 - 7.6e-23 81.5 0.7 4.8e-22 78.9 0.4 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK18810.1 - 3e-12 46.5 0.0 1.2e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 KKK18810.1 - 2.9e-10 39.8 0.0 1e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 KKK18810.1 - 1.2e-09 38.0 0.0 7.6e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PTPlike_phytase PF14566.1 KKK18810.1 - 0.00047 20.2 0.0 0.00079 19.4 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Ser_hydrolase PF06821.8 KKK18810.1 - 0.0011 18.5 0.0 0.0041 16.7 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Y_phosphatase PF00102.22 KKK18810.1 - 0.0012 18.2 0.0 0.0029 16.9 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Thioesterase PF00975.15 KKK18810.1 - 0.01 16.0 0.1 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 KKK18810.1 - 0.021 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase FSH1 PF03959.8 KKK18810.1 - 0.026 13.9 0.0 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF2305 PF10230.4 KKK18810.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 KKK18810.1 - 0.14 11.0 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 KKK18810.1 - 0.18 11.3 0.0 0.67 9.4 0.0 1.9 1 1 0 1 1 1 0 PGAP1-like protein Ribosomal_S19e PF01090.14 KKK18811.1 - 2.6e-57 192.1 0.3 3e-57 191.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e SnoaL_4 PF13577.1 KKK18812.1 - 0.043 13.7 0.1 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Pex2_Pex12 PF04757.9 KKK18813.1 - 3.7e-41 141.0 0.9 3.7e-41 141.0 0.7 1.5 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KKK18813.1 - 0.00073 19.3 4.9 0.0017 18.2 3.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KKK18813.1 - 0.74 9.8 8.6 0.85 9.6 3.8 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Na_trans_assoc PF06512.8 KKK18813.1 - 4 7.3 8.6 0.44 10.4 0.2 2.7 2 1 1 3 3 3 0 Sodium ion transport-associated Ldh_2 PF02615.9 KKK18814.1 - 2.6e-100 335.4 0.0 3.1e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase ILVD_EDD PF00920.16 KKK18815.1 - 2.5e-203 676.2 1.3 2.9e-203 676.0 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family NAD_Gly3P_dh_N PF01210.18 KKK18816.1 - 0.11 12.1 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MDM31_MDM32 PF08118.6 KKK18820.1 - 2e-202 673.1 0.3 2.4e-202 672.9 0.2 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Peptidase_M61 PF05299.7 KKK18820.1 - 0.13 12.2 0.0 0.98 9.4 0.0 2.2 2 0 0 2 2 2 0 M61 glycyl aminopeptidase DUF3450 PF11932.3 KKK18821.1 - 0.0021 17.3 0.4 0.0039 16.4 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Nitroreductase PF00881.19 KKK18821.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Nitroreductase family RhoGAP PF00620.22 KKK18822.1 - 9e-42 142.2 0.1 1.8e-41 141.2 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KKK18822.1 - 2.3e-12 47.0 0.0 4.7e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KKK18822.1 - 2.8e-07 30.7 0.0 5.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KKK18822.1 - 0.01 15.8 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Dpoe2NT PF12213.3 KKK18822.1 - 0.083 12.8 0.1 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal Proteasome PF00227.21 KKK18823.1 - 3.7e-27 94.8 0.0 4.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 KKK18824.1 - 9.8e-33 112.0 1.6 1.1e-32 111.9 0.2 1.7 2 0 0 2 2 2 1 HCNGP-like protein Proteasome PF00227.21 KKK18825.1 - 2.1e-33 115.2 0.1 7.5e-33 113.4 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit KH_1 PF00013.24 KKK18826.1 - 9.7e-06 25.1 1.7 2.2e-05 24.0 1.2 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KKK18826.1 - 0.012 15.2 2.3 0.022 14.4 0.5 2.2 2 0 0 2 2 2 0 KH domain Lipase_3 PF01764.20 KKK18827.1 - 2.2e-31 108.3 0.0 3.5e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) WD40 PF00400.27 KKK18827.1 - 2.4e-18 65.2 7.6 9.8e-08 31.6 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat PGAP1 PF07819.8 KKK18827.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KKK18827.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK18827.1 - 0.003 17.4 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KKK18827.1 - 0.0073 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Cutinase PF01083.17 KKK18827.1 - 0.09 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase Rax2 PF12768.2 KKK18827.1 - 0.11 11.7 0.0 0.89 8.7 0.0 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Autophagy_act_C PF03987.10 KKK18828.1 - 3.6e-13 49.4 0.1 6.7e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_5 PF13893.1 KKK18829.1 - 8.3e-11 41.5 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK18829.1 - 2.8e-09 36.4 0.0 6.4e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK18829.1 - 6.4e-06 26.0 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAA_hydrolase PF01557.13 KKK18830.1 - 7.5e-61 205.3 0.0 9.4e-61 205.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HSP20 PF00011.16 KKK18831.1 - 2.9e-16 59.1 0.9 9.7e-13 47.8 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DREPP PF05558.7 KKK18831.1 - 0.24 11.2 5.0 0.37 10.6 3.4 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Glyco_hydro_7 PF00840.15 KKK18832.1 - 2.3e-145 484.3 15.3 2.8e-145 483.9 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Lipid_bd PF12888.2 KKK18832.1 - 0.081 12.7 1.4 0.097 12.4 0.2 1.7 2 0 0 2 2 2 0 Lipid-binding putative hydrolase Metallothio PF00131.15 KKK18832.1 - 1 9.3 15.1 0.17 11.7 0.6 3.1 3 0 0 3 3 3 0 Metallothionein AMP-binding PF00501.23 KKK18833.1 - 4.8e-58 196.5 0.0 5.5e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK18833.1 - 2.3e-12 47.6 0.0 4.2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Topoisom_bac PF01131.15 KKK18835.1 - 2.9e-88 296.4 0.0 4.6e-88 295.7 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KKK18835.1 - 2.8e-19 68.9 0.0 5.7e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF4149 PF13664.1 KKK18836.1 - 3.9e-25 87.8 5.0 9.6e-25 86.5 1.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) PepSY_TM_3 PF13706.1 KKK18836.1 - 0.26 10.7 3.0 8.8 5.8 0.2 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix Peptidase_M41 PF01434.13 KKK18837.1 - 3.9e-73 245.4 0.0 4.5e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M41 DUF1295 PF06966.7 KKK18838.1 - 3.2e-42 144.4 6.2 4.1e-42 144.0 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Pkinase PF00069.20 KKK18841.1 - 7.7e-14 51.4 0.0 2e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KKK18841.1 - 0.002 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KKK18841.1 - 0.0045 16.0 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KKK18841.1 - 0.0077 15.3 0.1 0.019 14.0 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KKK18841.1 - 0.022 13.7 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KKK18841.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ku PF02735.11 KKK18842.1 - 4.7e-28 97.9 0.0 8.1e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KKK18842.1 - 1.5e-20 73.6 0.0 2.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 KKK18842.1 - 4e-18 65.4 0.1 2.1e-17 63.1 0.0 2.2 2 0 0 2 2 2 1 Ku C terminal domain like VWA_2 PF13519.1 KKK18842.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain MFS_1 PF07690.11 KKK18844.1 - 6e-27 94.2 77.8 5.7e-23 81.2 33.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily LIM PF00412.17 KKK18845.1 - 7.7e-14 51.5 15.8 5.9e-08 32.6 3.3 2.8 2 1 0 2 2 2 2 LIM domain DUF2321 PF10083.4 KKK18845.1 - 0.82 9.1 6.9 0.13 11.7 1.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Ceramidase PF05875.7 KKK18847.1 - 3.4e-98 327.9 8.7 4.2e-97 324.3 6.0 1.9 1 1 0 1 1 1 1 Ceramidase DUF4401 PF14351.1 KKK18847.1 - 0.15 11.0 10.6 0.36 9.7 6.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) Mito_carr PF00153.22 KKK18848.1 - 4.7e-55 183.2 2.7 4.5e-19 67.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BRCT PF00533.21 KKK18849.1 - 9.5e-29 99.3 0.0 2.1e-06 27.7 0.0 6.5 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KKK18849.1 - 2.7e-26 91.2 0.2 4.8e-19 67.9 0.2 5.1 4 1 0 4 4 4 3 twin BRCT domain Abhydrolase_6 PF12697.2 KKK18850.1 - 2e-29 103.1 0.5 3.3e-29 102.3 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK18850.1 - 2e-07 30.8 0.0 4.8e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK18850.1 - 4.7e-05 23.0 0.0 7.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KKK18850.1 - 0.043 13.4 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Methyltransf_4 PF02390.12 KKK18851.1 - 4.8e-49 166.0 0.0 5.6e-36 123.4 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_26 PF13659.1 KKK18851.1 - 7.9e-05 22.6 0.0 0.00021 21.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18851.1 - 0.00034 21.1 0.0 0.00079 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KKK18851.1 - 0.0061 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 KKK18851.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18851.1 - 0.015 15.6 0.0 0.048 14.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 KKK18851.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KKK18851.1 - 0.02 14.2 0.0 0.076 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KKK18851.1 - 0.031 14.7 0.0 0.095 13.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain RNR_inhib PF08591.5 KKK18851.1 - 0.042 14.7 1.4 0.063 14.1 0.2 1.9 2 0 0 2 2 2 0 Ribonucleotide reductase inhibitor Suppressor_APC PF11414.3 KKK18851.1 - 0.059 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein ESCRT-II PF05871.7 KKK18852.1 - 1.9e-49 167.1 0.7 2.7e-49 166.6 0.5 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit GTP_EFTU PF00009.22 KKK18875.1 - 1.9e-43 148.1 0.0 3.2e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KKK18875.1 - 2.4e-19 69.3 0.0 6.1e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KKK18875.1 - 1.2e-06 28.5 0.4 3e-06 27.2 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KKK18875.1 - 0.0075 16.2 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.4 KKK18875.1 - 0.56 8.7 12.6 0.79 8.2 8.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein G-alpha PF00503.15 KKK18875.1 - 0.74 8.4 7.5 2.6 6.6 5.2 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Med15 PF09606.5 KKK18875.1 - 6 4.9 37.9 9.7 4.2 26.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal WGG PF10273.4 KKK18876.1 - 1.4e-30 105.2 0.3 2.2e-30 104.5 0.2 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 NOA36 PF06524.7 KKK18876.1 - 0.0054 16.0 2.3 0.0071 15.6 1.6 1.1 1 0 0 1 1 1 1 NOA36 protein RRP7 PF12923.2 KKK18876.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.0 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Nro1 PF12753.2 KKK18876.1 - 0.24 10.3 3.0 0.33 9.8 2.1 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 RXT2_N PF08595.6 KKK18876.1 - 0.67 9.7 4.1 1.1 9.0 2.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.1 KKK18876.1 - 3 8.0 10.3 1.7 8.8 3.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 KKK18876.1 - 5.5 7.3 14.2 0.33 11.2 6.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 KKK18876.1 - 9.8 3.9 9.6 11 3.8 6.6 1.0 1 0 0 1 1 1 0 Nop14-like family BSD PF03909.12 KKK18877.1 - 1.4e-15 56.7 1.4 2.8e-15 55.8 1.0 1.5 1 0 0 1 1 1 1 BSD domain Legionella_OMP PF05150.7 KKK18877.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Suf PF05843.9 KKK18877.1 - 0.27 10.8 2.4 0.59 9.8 1.7 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ran-binding PF05508.6 KKK18878.1 - 4.2e-118 393.6 1.0 5.4e-118 393.3 0.7 1.1 1 0 0 1 1 1 1 RanGTP-binding protein Pkinase PF00069.20 KKK18879.1 - 0.015 14.4 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.6 KKK18879.1 - 0.034 13.3 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Destabilase PF05497.7 KKK18880.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Destabilase Ras PF00071.17 KKK18882.1 - 6.3e-49 165.4 1.4 4.2e-47 159.5 0.3 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KKK18882.1 - 5e-12 46.3 0.1 1.4e-11 44.8 0.1 1.8 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK18882.1 - 1.6e-10 40.4 0.1 2.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK18882.1 - 4.6e-08 32.7 0.0 5.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KKK18882.1 - 3.4e-05 23.0 0.2 6.5e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Mitofilin PF09731.4 KKK18883.1 - 3.6e-154 514.6 10.3 9.1e-154 513.3 7.1 1.7 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Glyco_hydro_3 PF00933.16 KKK18884.1 - 1.2e-86 290.3 0.0 1.7e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK18884.1 - 8e-51 172.7 0.0 3.7e-50 170.5 0.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain zf-RING_2 PF13639.1 KKK18885.1 - 2.3e-08 33.6 2.9 5e-06 26.2 0.5 2.5 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 KKK18885.1 - 1.7e-06 28.0 0.5 3.7e-05 23.7 0.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KKK18885.1 - 4e-05 23.3 1.9 0.00017 21.3 0.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 KKK18885.1 - 0.0061 16.2 1.1 0.015 14.9 0.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_4 PF15227.1 KKK18885.1 - 0.027 14.3 2.4 0.027 14.3 1.6 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KKK18885.1 - 0.04 13.8 4.7 0.25 11.3 1.5 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KKK18885.1 - 0.046 13.7 2.4 0.046 13.7 1.7 1.8 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_2 PF13923.1 KKK18885.1 - 0.07 13.1 4.0 0.86 9.6 1.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK18885.1 - 0.077 12.7 0.5 0.077 12.7 0.4 2.4 3 0 0 3 3 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK18885.1 - 0.14 11.8 3.7 0.62 9.7 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ANAPC15 PF15243.1 KKK18885.1 - 0.36 10.9 16.3 0.68 10.0 11.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 zf-C3HC4 PF00097.20 KKK18885.1 - 0.52 10.0 9.7 0.1 12.2 1.0 2.5 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 KKK18885.1 - 0.6 9.4 3.2 1.5 8.1 2.2 1.7 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KKK18885.1 - 1 9.4 5.3 0.15 12.0 0.9 1.7 2 0 0 2 2 2 0 RING-like domain zf-RING_4 PF14570.1 KKK18885.1 - 1.1 8.8 6.4 0.51 9.9 1.3 2.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain FYDLN_acid PF09538.5 KKK18885.1 - 3.3 8.3 21.8 0.53 10.8 11.4 2.3 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) Citrate_synt PF00285.16 KKK18886.1 - 5.2e-98 328.0 0.0 6.2e-98 327.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ABC_tran PF00005.22 KKK18887.1 - 4.7e-47 159.7 0.0 1.3e-25 90.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KKK18887.1 - 5.8e-15 56.0 1.4 0.004 17.1 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KKK18887.1 - 6.8e-11 41.8 0.3 0.0064 15.7 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 KKK18887.1 - 1e-06 29.2 0.0 0.0036 17.7 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein SbcCD_C PF13558.1 KKK18887.1 - 1.9e-06 27.6 0.0 0.13 12.1 0.0 3.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KKK18887.1 - 3.1e-06 26.6 2.1 0.069 12.6 0.2 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain Chromo PF00385.19 KKK18887.1 - 3.7e-06 26.5 0.0 7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.18 KKK18887.1 - 5.1e-06 26.4 0.0 0.048 13.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KKK18887.1 - 5.2e-06 25.7 0.0 0.026 13.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KKK18887.1 - 6.4e-06 26.6 0.0 0.077 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KKK18887.1 - 8.6e-06 25.0 0.0 0.14 11.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KKK18887.1 - 8.6e-06 25.9 0.0 0.026 14.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KKK18887.1 - 2.9e-05 23.6 1.2 1.1 8.5 0.0 4.1 4 1 0 4 4 4 2 AAA-like domain AAA_17 PF13207.1 KKK18887.1 - 4.8e-05 24.1 0.0 0.55 11.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KKK18887.1 - 0.00017 21.3 0.4 0.1 12.2 0.0 2.8 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.12 KKK18887.1 - 0.00028 20.7 1.5 0.26 11.0 0.1 3.9 4 1 0 4 4 3 1 Domain of unknown function DUF87 AAA_13 PF13166.1 KKK18887.1 - 0.00041 18.9 0.0 0.025 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KKK18887.1 - 0.00071 19.4 0.1 0.1 12.4 0.0 3.2 2 1 0 2 2 2 1 Dynamin family AAA_28 PF13521.1 KKK18887.1 - 0.001 19.0 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KKK18887.1 - 0.0012 18.5 0.0 2.1 8.0 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KKK18887.1 - 0.0013 18.6 0.0 2.5 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KKK18887.1 - 0.0018 18.4 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 KKK18887.1 - 0.015 14.0 0.2 4.3 6.0 0.1 2.4 2 0 0 2 2 2 0 ArgK protein AAA_25 PF13481.1 KKK18887.1 - 0.027 13.8 0.0 4.7 6.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KKK18887.1 - 0.032 13.7 1.1 2.3 7.6 0.1 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 KKK18887.1 - 0.056 12.9 0.1 6.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KKK18887.1 - 0.082 13.1 0.0 3.7 7.7 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KKK18887.1 - 0.082 11.8 0.1 5.8 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KKK18887.1 - 0.095 12.6 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KKK18887.1 - 0.1 11.5 0.0 9.6 5.1 0.0 2.3 2 0 0 2 2 2 0 Septin Asp PF00026.18 KKK18888.1 - 3.4e-49 167.8 0.0 4.3e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK18888.1 - 5.3e-05 23.2 0.2 0.00031 20.7 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KKK18888.1 - 0.0019 18.6 0.1 0.057 13.9 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease DUF3443 PF11925.3 KKK18888.1 - 0.051 12.2 0.8 0.14 10.8 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3443) DUF1365 PF07103.6 KKK18889.1 - 1.7e-08 33.8 0.2 5.7e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1365) MARVEL PF01284.18 KKK18891.1 - 2.2e-12 46.9 21.3 3.2e-12 46.4 14.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain H_PPase PF03030.11 KKK18891.1 - 0.011 14.0 1.0 0.014 13.6 0.7 1.0 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF817 PF05675.7 KKK18891.1 - 0.16 11.3 9.4 0.15 11.4 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF817) 7TMR-DISM_7TM PF07695.6 KKK18891.1 - 0.2 11.3 19.9 0.51 9.9 3.5 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling Abhydrolase_3 PF07859.8 KKK18892.1 - 4.5e-55 186.4 0.3 5.7e-55 186.1 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK18892.1 - 5.1e-14 51.7 0.0 6.8e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK18892.1 - 2.6e-07 30.4 0.3 3.5e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KKK18892.1 - 0.00016 21.9 0.1 0.00022 21.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 KKK18892.1 - 0.001 18.3 0.0 0.0031 16.7 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KKK18892.1 - 0.0014 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase MOZART2 PF12926.2 KKK18892.1 - 0.079 12.5 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Esterase PF00756.15 KKK18892.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Putative esterase COesterase PF00135.23 KKK18892.1 - 0.089 11.4 1.0 0.11 11.1 0.1 1.6 2 0 0 2 2 2 0 Carboxylesterase family BAAT_C PF08840.6 KKK18892.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pyr_redox_3 PF13738.1 KKK18893.1 - 3.1e-14 53.5 0.5 1.5e-11 44.7 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK18893.1 - 7.7e-06 25.9 0.0 5.1e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK18893.1 - 0.00026 19.3 0.8 0.0031 15.7 0.0 2.6 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK18893.1 - 0.00051 19.0 0.2 0.023 13.6 0.1 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK18893.1 - 0.11 12.5 0.1 0.3 11.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trehalose_PPase PF02358.11 KKK18893.1 - 0.11 11.3 0.0 0.51 9.1 0.0 1.9 2 0 0 2 2 2 0 Trehalose-phosphatase Pyr_redox PF00070.22 KKK18893.1 - 0.21 12.0 0.3 0.64 10.4 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK18894.1 - 2e-26 93.3 0.0 3.1e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK18894.1 - 2.7e-14 52.9 0.0 2.2e-10 40.4 0.0 3.2 2 1 1 3 3 3 2 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KKK18894.1 - 1.1e-13 50.2 0.0 3.8e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KKK18894.1 - 1.4e-10 41.4 0.0 5.7e-09 36.1 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK18894.1 - 3.3e-10 39.4 0.2 5.8e-08 32.0 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KKK18894.1 - 2.5e-08 33.8 2.7 0.00017 21.3 0.1 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KKK18894.1 - 1.3e-07 31.8 0.2 0.0065 16.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK18894.1 - 2.4e-07 29.9 0.0 5e-05 22.3 0.0 3.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK18894.1 - 1.5e-06 27.5 0.0 0.0009 18.3 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.7 KKK18894.1 - 4e-06 25.9 0.0 0.00026 20.0 0.0 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 KKK18894.1 - 9e-06 24.4 0.2 0.058 11.8 0.0 3.0 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.19 KKK18894.1 - 0.00027 19.9 0.0 0.004 16.0 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 KKK18894.1 - 0.00032 19.8 0.1 0.0083 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 KKK18894.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KKK18894.1 - 0.04 14.1 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding CPSase_L_chain PF00289.17 KKK18894.1 - 0.059 13.4 0.0 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain HK PF02110.10 KKK18894.1 - 0.1 11.7 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family adh_short PF00106.20 KKK18895.1 - 4e-22 78.8 0.2 5.7e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK18895.1 - 1.3e-12 48.0 0.0 1.6e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KKK18895.1 - 0.002 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding PAE PF03283.8 KKK18895.1 - 0.0081 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase DUF1776 PF08643.5 KKK18895.1 - 0.0083 15.2 0.0 0.15 11.1 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) ketoacyl-synt PF00109.21 KKK18896.1 - 8.2e-72 241.7 0.2 8.2e-72 241.7 0.1 2.4 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK18896.1 - 7.2e-64 216.1 0.0 1.4e-63 215.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KKK18896.1 - 3.3e-40 138.1 1.3 6.7e-40 137.0 0.9 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KKK18896.1 - 1.1e-34 118.8 0.1 4.7e-34 116.7 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 KKK18896.1 - 1.2e-30 106.5 0.0 2.7e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KKK18896.1 - 4.3e-18 65.7 0.1 6.3e-17 62.0 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.7 KKK18896.1 - 5e-17 62.2 0.0 1.1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK18896.1 - 4.9e-10 39.3 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18896.1 - 9.5e-08 32.6 0.0 4.1e-07 30.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18896.1 - 6.4e-07 29.7 0.0 1.9e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK18896.1 - 4.7e-06 26.2 0.0 9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KKK18896.1 - 1.3e-05 25.3 0.3 3.4e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 KKK18896.1 - 0.0087 16.4 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK18896.1 - 0.0098 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KKK18896.1 - 0.011 14.8 0.1 0.011 14.8 0.1 1.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KKK18896.1 - 0.021 14.4 1.3 0.079 12.6 0.5 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.4 KKK18896.1 - 0.51 9.7 0.0 1 8.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FAD_binding_3 PF01494.14 KKK18897.1 - 1.1e-25 90.4 6.0 5.2e-24 84.9 4.2 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK18897.1 - 2.1e-06 26.9 0.1 0.0017 17.3 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK18897.1 - 0.00033 19.6 0.2 0.00033 19.6 0.2 1.8 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 KKK18897.1 - 0.002 18.2 0.1 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK18897.1 - 0.003 17.5 1.6 0.0048 16.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK18897.1 - 0.0068 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family ThiF PF00899.16 KKK18897.1 - 0.11 12.3 0.7 0.25 11.1 0.5 1.6 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 KKK18897.1 - 0.14 12.5 0.1 0.99 9.8 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 KKK18898.1 - 7.4e-79 265.4 23.2 8.2e-79 265.2 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK18898.1 - 6.5e-37 127.0 53.3 3.5e-34 118.0 20.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK18898.1 - 6.2e-06 24.6 7.4 1.8e-05 23.1 2.8 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KKK18898.1 - 0.00017 20.1 4.6 0.00017 20.1 3.2 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KKK18898.1 - 0.027 14.2 1.7 0.07 12.9 0.0 2.5 3 0 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.8 KKK18898.1 - 1.5 6.8 14.2 0.015 13.4 1.8 2.9 3 1 1 4 4 4 0 Transmembrane secretion effector Fungal_trans PF04082.13 KKK18900.1 - 1.8e-13 49.9 0.0 6.4e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 KKK18901.1 - 1.9e-52 177.8 0.0 2.4e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 KKK18903.1 - 3.5e-57 193.9 0.0 5.2e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MMR_HSR1 PF01926.18 KKK18904.1 - 9.7e-07 28.7 0.1 5.9e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 KKK18904.1 - 2.2e-06 28.1 3.4 0.0043 17.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KKK18904.1 - 3.3e-06 26.3 0.0 8.8e-06 24.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KKK18904.1 - 0.00034 19.7 0.0 0.54 9.3 0.0 2.7 2 0 0 2 2 2 2 AIG1 family AAA_29 PF13555.1 KKK18904.1 - 0.00063 19.2 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KKK18904.1 - 0.00086 19.3 0.0 0.01 15.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KKK18904.1 - 0.0017 17.8 0.0 0.0041 16.6 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 KKK18904.1 - 0.0031 16.4 0.0 0.0066 15.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Snf7 PF03357.16 KKK18904.1 - 0.0072 15.7 3.4 0.0072 15.7 2.3 2.1 2 0 0 2 2 2 1 Snf7 Dynamin_N PF00350.18 KKK18904.1 - 0.02 14.7 4.6 3.1 7.6 0.0 3.7 3 0 0 3 3 3 0 Dynamin family GTP_EFTU PF00009.22 KKK18904.1 - 0.021 14.2 0.0 0.071 12.5 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KKK18904.1 - 0.046 14.0 2.6 0.38 11.0 0.0 3.1 3 0 0 3 3 3 0 ABC transporter AAA_10 PF12846.2 KKK18904.1 - 0.083 12.3 1.2 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 KKK18904.1 - 0.098 13.4 1.1 1.6 9.5 0.0 3.5 5 0 0 5 5 3 0 AAA domain RNA_helicase PF00910.17 KKK18904.1 - 0.1 12.7 0.1 0.72 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 KKK18904.1 - 0.15 11.8 0.0 0.15 11.8 0.0 3.6 4 1 0 4 4 3 0 Domain of unknown function DUF87 DUF948 PF06103.6 KKK18904.1 - 0.45 10.4 3.8 0.54 10.1 0.3 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 KKK18904.1 - 3.4 7.5 13.2 6.3 6.6 0.1 4.3 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Fic PF02661.13 KKK18906.1 - 0.11 13.2 0.1 0.23 12.1 0.1 1.5 1 0 0 1 1 1 0 Fic/DOC family Methyltransf_11 PF08241.7 KKK18907.1 - 5.9e-16 58.7 0.0 1.5e-15 57.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK18907.1 - 1.1e-14 54.5 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK18907.1 - 8.9e-12 44.8 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18907.1 - 2.2e-11 44.3 0.0 4.8e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18907.1 - 8.1e-11 42.1 0.0 3.6e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK18907.1 - 7.1e-09 36.0 0.0 1.7e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK18907.1 - 8.5e-08 32.2 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KKK18907.1 - 5e-06 25.7 0.0 6.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KKK18907.1 - 0.00061 19.1 0.0 0.00097 18.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.11 KKK18907.1 - 0.0096 14.8 0.0 0.045 12.6 0.0 1.8 1 1 1 2 2 2 1 mRNA capping enzyme MetW PF07021.7 KKK18907.1 - 0.026 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 KKK18907.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) FmrO PF07091.6 KKK18907.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Aegerolysin PF06355.8 KKK18908.1 - 1.1e-36 125.6 0.4 1.2e-36 125.4 0.3 1.0 1 0 0 1 1 1 1 Aegerolysin Zn_clus PF00172.13 KKK18909.1 - 0.00026 20.8 5.2 0.00072 19.4 3.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KKK18911.1 - 1.2e-49 168.6 0.0 1.5e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Reoviridae_Vp9 PF08978.5 KKK18911.1 - 0.058 12.3 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Reoviridae VP9 GMC_oxred_C PF05199.8 KKK18912.1 - 8.3e-10 39.1 0.0 2.8e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Abhydrolase_6 PF12697.2 KKK18912.1 - 4.7e-08 33.1 0.1 2.1e-06 27.8 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family GMC_oxred_N PF00732.14 KKK18912.1 - 2.4e-07 30.1 0.0 5.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK18912.1 - 0.00032 19.6 0.7 0.0005 19.0 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK18912.1 - 0.0014 18.6 0.1 0.0046 16.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK18912.1 - 0.01 16.2 0.1 0.029 14.7 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK18912.1 - 0.036 13.9 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_56 PF07429.6 KKK18912.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 FAD_oxidored PF12831.2 KKK18912.1 - 0.82 8.6 4.9 1.4 7.9 3.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 KKK18913.1 - 3.5e-09 35.9 0.0 9.7e-09 34.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK18913.1 - 4.1e-08 33.1 14.9 0.0012 19.1 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK18913.1 - 1.4e-06 28.2 18.4 1.7e-06 27.9 3.5 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK18913.1 - 2.5e-06 27.4 11.9 0.012 15.9 2.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KKK18913.1 - 0.0043 16.6 0.2 0.0043 16.6 0.2 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type DUF500 PF04366.7 KKK18914.1 - 3e-45 152.7 0.0 4.9e-45 152.0 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Dicty_REP PF05086.7 KKK18915.1 - 2.2 5.9 8.0 2.7 5.6 5.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2235 PF09994.4 KKK18916.1 - 1.1e-68 231.5 0.0 1.7e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KKK18916.1 - 0.039 13.7 0.0 0.075 12.7 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 KKK18917.1 - 2.3e-104 349.8 8.2 2.8e-104 349.5 5.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PHO4 PF01384.15 KKK18918.1 - 2.9e-113 377.8 11.5 3.7e-113 377.4 8.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family cobW PF02492.14 KKK18918.1 - 4.9e-47 159.6 4.9 8.4e-36 123.0 0.5 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KKK18918.1 - 2.7e-20 71.8 0.3 4.4e-16 58.3 0.0 2.7 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 KKK18918.1 - 0.0096 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 KKK18918.1 - 0.011 15.2 0.0 0.04 13.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 KKK18918.1 - 0.021 14.5 0.1 0.051 13.2 0.1 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KKK18918.1 - 0.027 14.6 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK18918.1 - 0.037 13.9 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KKK18918.1 - 0.046 12.6 0.1 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 KKK18918.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 KKK18918.1 - 0.089 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KKK18918.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PgaD PF13994.1 KKK18918.1 - 0.18 11.2 2.9 0.52 9.7 2.0 1.8 1 0 0 1 1 1 0 PgaD-like protein Zeta_toxin PF06414.7 KKK18918.1 - 0.19 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KKK18918.1 - 0.35 11.1 0.0 0.35 11.1 0.0 2.3 3 0 0 3 3 2 0 AAA domain HHH_5 PF14520.1 KKK18919.1 - 2.9e-06 27.3 0.0 0.00042 20.4 0.0 2.3 1 1 0 1 1 1 1 Helix-hairpin-helix domain UPF0181 PF03701.9 KKK18919.1 - 0.16 11.2 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) FAD_binding_3 PF01494.14 KKK18920.1 - 4.6e-73 246.3 0.0 6.8e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK18920.1 - 0.00035 19.7 0.0 0.00082 18.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KKK18920.1 - 0.0023 17.9 0.1 0.0056 16.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK18920.1 - 0.0064 16.4 0.0 0.058 13.2 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK18920.1 - 0.0078 15.1 0.0 0.022 13.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK18920.1 - 0.0084 16.5 0.0 0.034 14.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK18920.1 - 0.0089 14.9 0.0 0.33 9.7 0.0 2.3 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KKK18920.1 - 0.012 14.1 0.0 0.021 13.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KKK18920.1 - 0.014 15.4 0.0 0.039 14.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK18920.1 - 0.13 11.1 0.3 0.45 9.3 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein IF-2B PF01008.12 KKK18921.1 - 9.2e-62 208.5 0.3 1.2e-59 201.6 0.2 2.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family NIF PF03031.13 KKK18922.1 - 1.6e-55 187.1 0.0 2.8e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Macoilin PF09726.4 KKK18922.1 - 0.082 11.1 2.9 0.12 10.6 2.0 1.3 1 0 0 1 1 1 0 Transmembrane protein Ribosom_S12_S23 PF00164.20 KKK18925.1 - 1.2e-40 137.6 0.4 1.5e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 zf-AN1 PF01428.11 KKK18938.1 - 2.7e-11 43.1 12.6 3.9e-11 42.6 8.8 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4187 PF13821.1 KKK18938.1 - 0.046 13.3 2.5 0.071 12.7 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Pkinase PF00069.20 KKK18939.1 - 3.6e-20 72.2 0.0 8.4e-20 71.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18939.1 - 0.00038 19.5 0.1 0.00089 18.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1754 PF08555.5 KKK18940.1 - 5.1e-17 62.2 6.8 5.1e-17 62.2 4.7 1.5 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Spt5_N PF11942.3 KKK18940.1 - 0.19 12.3 8.1 0.094 13.3 4.0 1.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Aldo_ket_red PF00248.16 KKK18941.1 - 1.5e-54 184.7 0.0 1.7e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RBD PF02196.10 KKK18941.1 - 0.14 11.9 0.0 4.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Raf-like Ras-binding domain EamA PF00892.15 KKK18942.1 - 4.2e-14 52.6 25.5 3.6e-08 33.5 12.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family Metallophos PF00149.23 KKK18942.1 - 4.8e-09 35.8 1.1 1.5e-08 34.3 0.8 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EmrE PF13536.1 KKK18942.1 - 4.3e-07 30.1 16.4 8.7e-05 22.6 0.0 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter Metallophos_2 PF12850.2 KKK18942.1 - 1.1e-05 25.3 0.0 2.6e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF914 PF06027.7 KKK18942.1 - 2.8e-05 23.1 1.0 4.5e-05 22.4 0.7 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) Nuc_sug_transp PF04142.10 KKK18942.1 - 0.0021 17.2 0.2 0.0054 15.8 0.0 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 KKK18942.1 - 0.0034 16.3 1.0 0.0034 16.3 0.7 1.8 1 1 1 2 2 2 2 UAA transporter family TPT PF03151.11 KKK18942.1 - 0.03 13.9 18.9 0.057 13.0 6.3 2.8 3 0 0 3 3 3 0 Triose-phosphate Transporter family DUF202 PF02656.10 KKK18942.1 - 0.43 10.8 14.1 0.08 13.1 1.5 4.3 3 2 1 4 4 4 0 Domain of unknown function (DUF202) Actin PF00022.14 KKK18943.1 - 3.8e-116 387.7 0.0 5e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KKK18943.1 - 0.018 13.6 0.0 0.079 11.5 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein DUF1325 PF07039.6 KKK18944.1 - 1.5e-30 105.4 0.0 2.3e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain TUDOR PF00567.19 KKK18944.1 - 0.16 11.7 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Tudor domain PMI_typeI PF01238.16 KKK18945.1 - 7e-149 495.8 0.0 8.2e-149 495.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KKK18945.1 - 0.02 14.3 0.1 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.14 KKK18945.1 - 0.058 13.0 0.0 15 5.2 0.0 2.9 3 0 0 3 3 3 0 AraC-like ligand binding domain Coatomer_E PF04733.9 KKK18946.1 - 2.3e-38 132.0 0.5 2.6e-38 131.8 0.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KKK18946.1 - 9.5e-06 25.8 4.3 0.00042 20.6 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK18946.1 - 2.9e-05 24.3 4.1 0.00045 20.6 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK18946.1 - 0.00038 21.0 10.1 0.0049 17.5 0.6 3.1 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK18946.1 - 0.002 17.8 3.1 0.024 14.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK18946.1 - 0.003 17.1 0.3 0.05 13.2 0.0 2.5 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KKK18946.1 - 0.02 14.4 0.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK18946.1 - 0.025 14.4 1.7 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma70_r3 PF04539.11 KKK18946.1 - 0.33 10.8 2.3 4.6 7.1 0.8 2.8 2 1 0 2 2 2 0 Sigma-70 region 3 TPR_4 PF07721.9 KKK18946.1 - 1.3 9.6 5.8 0.86 10.2 0.4 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Reprolysin_5 PF13688.1 KKK18947.1 - 3.7e-31 108.6 1.4 3.7e-31 108.6 1.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KKK18947.1 - 5.1e-29 101.2 0.2 8.2e-29 100.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KKK18947.1 - 3.4e-14 53.2 0.3 7.7e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KKK18947.1 - 3.6e-13 50.1 0.6 3e-12 47.1 0.0 2.4 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 KKK18947.1 - 0.00012 21.7 0.1 0.0008 19.0 0.1 2.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KKK18947.1 - 0.0015 18.2 0.0 0.072 12.8 0.0 2.2 2 0 0 2 2 2 1 Reprolysin family propeptide HxxPF_rpt PF13745.1 KKK18947.1 - 0.0016 18.7 0.0 0.42 10.9 0.0 3.1 3 0 0 3 3 3 1 HxxPF-repeated domain NAD_binding_2 PF03446.10 KKK18948.1 - 2.5e-29 102.2 0.2 3.5e-29 101.7 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KKK18948.1 - 4.2e-11 42.9 0.0 8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KKK18948.1 - 0.0002 21.7 0.0 0.00083 19.7 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF3425 PF11905.3 KKK18949.1 - 2.6e-37 127.7 3.1 4.8e-37 126.8 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KKK18949.1 - 0.0011 18.8 9.4 0.0063 16.4 4.6 2.3 1 1 1 2 2 2 1 bZIP transcription factor DUF904 PF06005.7 KKK18949.1 - 0.26 11.5 4.5 0.48 10.7 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 KKK18949.1 - 0.34 10.7 12.3 2.4 8.0 8.5 2.1 1 1 0 1 1 1 0 Basic region leucine zipper GTP_cyclohydro2 PF00925.15 KKK18950.1 - 9.4e-57 190.9 0.0 3.6e-52 175.9 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Tubulin PF00091.20 KKK18951.1 - 2.1e-69 233.6 0.0 3.2e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KKK18951.1 - 7.1e-45 152.1 1.1 7.7e-45 151.9 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Asp_Glu_race PF01177.17 KKK18951.1 - 5.6e-10 39.4 0.0 1.8e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Misat_Tub_SegII PF10644.4 KKK18951.1 - 7e-06 26.0 0.0 2.3e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain ERGIC_N PF13850.1 KKK18953.1 - 2e-24 85.3 0.0 3e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.7 KKK18953.1 - 0.0045 16.6 0.0 0.0088 15.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Pex24p PF06398.6 KKK18954.1 - 4.7e-54 183.5 0.0 5.4e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pkinase PF00069.20 KKK18955.1 - 1.4e-58 198.1 0.0 2e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18955.1 - 2.7e-20 72.5 0.0 4.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Phage_GP20 PF06810.6 KKK18955.1 - 0.073 12.5 0.0 0.97 8.8 0.0 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 APH PF01636.18 KKK18955.1 - 0.087 12.5 0.0 0.55 9.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC_tran PF00005.22 KKK18956.1 - 3.5e-42 143.9 0.0 6.7e-24 84.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK18956.1 - 1.6e-33 116.2 18.9 1.4e-17 64.0 5.3 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 KKK18956.1 - 1.2e-11 44.2 4.4 0.00014 21.2 0.1 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK18956.1 - 4.7e-10 39.9 0.1 0.0071 16.3 0.0 4.4 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KKK18956.1 - 2.8e-06 27.8 2.3 0.00023 21.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KKK18956.1 - 6.3e-06 26.3 2.2 0.015 15.4 0.0 3.4 3 1 0 3 3 2 2 AAA domain T2SE PF00437.15 KKK18956.1 - 5.9e-05 22.0 0.7 0.15 10.9 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 KKK18956.1 - 8.8e-05 21.9 0.1 0.35 10.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KKK18956.1 - 0.00013 22.0 9.5 0.059 13.3 0.3 4.1 3 2 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 KKK18956.1 - 0.00021 21.2 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KKK18956.1 - 0.00045 19.6 2.8 0.05 13.1 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 KKK18956.1 - 0.00052 20.5 0.0 0.043 14.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 KKK18956.1 - 0.0012 19.1 0.0 0.97 9.6 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KKK18956.1 - 0.0016 18.0 1.8 0.77 9.3 0.1 3.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KKK18956.1 - 0.0021 17.7 0.0 0.69 9.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 KKK18956.1 - 0.005 16.0 0.5 0.61 9.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KKK18956.1 - 0.0079 16.0 0.0 7.6 6.5 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 KKK18956.1 - 0.0096 14.4 0.4 9.9 4.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain cobW PF02492.14 KKK18956.1 - 0.014 14.8 1.4 0.69 9.3 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KKK18956.1 - 0.021 14.4 0.2 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 KKK18956.1 - 0.022 15.0 0.0 8.2 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KKK18956.1 - 0.046 13.2 0.0 0.82 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 KKK18956.1 - 0.066 12.1 0.1 2.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KKK18956.1 - 0.067 13.3 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 KKK18956.1 - 0.067 14.0 0.0 7.8 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KKK18956.1 - 0.11 12.1 0.4 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KKK18956.1 - 0.16 11.5 1.2 2.4 7.6 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KKK18956.1 - 0.24 11.1 1.6 3.3 7.5 0.1 3.1 3 0 0 3 3 3 0 Part of AAA domain ABC_ATPase PF09818.4 KKK18956.1 - 0.26 9.8 0.2 0.55 8.7 0.1 1.5 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PduV-EutP PF10662.4 KKK18956.1 - 0.3 10.5 1.3 5 6.5 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KKK18956.1 - 0.36 10.2 2.1 8.2 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain AAA_15 PF13175.1 KKK18956.1 - 0.37 9.7 0.1 0.95 8.4 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain DUF87 PF01935.12 KKK18956.1 - 0.65 9.7 4.4 0.16 11.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 Pkinase PF00069.20 KKK18958.1 - 2.5e-14 53.0 0.0 9.6e-14 51.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18958.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AsmA_1 PF13109.1 KKK18958.1 - 0.007 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 AsmA-like C-terminal region RNA_bind PF08675.6 KKK18960.1 - 0.037 14.0 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain AAT PF03417.11 KKK18961.1 - 3.3e-27 95.4 0.0 4.4e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 KKK18961.1 - 0.0009 19.5 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Pkinase PF00069.20 KKK18962.1 - 1.3e-24 86.7 0.0 2.4e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18962.1 - 8.2e-15 54.5 0.0 1.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.13 KKK18963.1 - 0.00031 19.8 5.5 0.00099 18.2 3.8 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SLAC1 PF03595.12 KKK18963.1 - 0.0059 15.3 1.6 0.0077 14.9 1.1 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Hemerythrin PF01814.18 KKK18964.1 - 8.5e-11 42.1 0.6 1.3e-10 41.5 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Acyl_transf_1 PF00698.16 KKK18965.1 - 1.2e-57 195.6 0.3 1.9e-57 195.0 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KKK18965.1 - 7.5e-56 189.4 0.0 1.5e-55 188.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KKK18965.1 - 9.2e-54 181.8 0.5 6.8e-53 179.0 0.2 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KKK18965.1 - 4.8e-39 133.9 1.9 1.9e-38 131.9 0.0 3.0 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KKK18965.1 - 6.2e-31 106.7 0.1 1.5e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KKK18965.1 - 6.8e-19 67.6 0.2 5.5e-18 64.7 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KKK18965.1 - 1.4e-17 63.9 0.0 5.8e-17 61.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK18965.1 - 3.4e-15 56.1 0.0 7.4e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KKK18965.1 - 2.6e-12 47.7 0.0 2.3e-11 44.7 0.0 2.7 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.21 KKK18965.1 - 4.4e-10 39.4 0.0 1.1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_31 PF13847.1 KKK18965.1 - 6.9e-10 38.7 0.0 3.9e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18965.1 - 4.8e-09 36.7 0.0 2.6e-08 34.4 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18965.1 - 5.4e-09 36.4 0.0 1.8e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KKK18965.1 - 4.3e-08 33.2 0.1 1.2e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KKK18965.1 - 8.6e-08 31.9 0.1 8.6e-07 28.6 0.0 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KKK18965.1 - 1.9e-05 23.8 0.0 4.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KKK18965.1 - 0.0018 17.7 0.0 0.023 14.1 0.0 2.7 3 0 0 3 3 3 1 Putative methyltransferase NodS PF05401.6 KKK18965.1 - 0.0053 16.1 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 KKK18965.1 - 0.017 15.1 0.0 0.049 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KKK18965.1 - 0.066 12.5 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Rad51 PF08423.6 KKK18967.1 - 0.00014 20.8 0.0 0.01 14.7 0.0 2.2 2 0 0 2 2 2 2 Rad51 DUF4276 PF14103.1 KKK18967.1 - 0.072 12.9 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) PALP PF00291.20 KKK18968.1 - 6.7e-50 170.0 0.7 7.6e-50 169.8 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TAF8_C PF10406.4 KKK18969.1 - 8.8e-22 76.9 1.3 1.8e-21 75.8 0.9 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 KKK18969.1 - 1.3e-09 37.5 0.0 6.3e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated Mitochondr_Som1 PF11093.3 KKK18970.1 - 6.7e-12 45.0 0.0 9.3e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 DUF2040 PF09745.4 KKK18971.1 - 7.3e-38 129.2 8.9 7.3e-38 129.2 6.2 3.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Isochorismatase PF00857.15 KKK18972.1 - 8.5e-40 136.5 0.0 1.9e-39 135.3 0.0 1.6 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.10 KKK18972.1 - 3e-06 27.6 0.0 6.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 KKK18972.1 - 0.075 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.8 KKK18973.1 - 1.4e-30 105.8 0.0 1.7e-14 53.7 0.0 2.0 2 0 0 2 2 2 2 Sedlin, N-terminal conserved region Sybindin PF04099.7 KKK18973.1 - 0.002 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Pab87_oct PF13969.1 KKK18973.1 - 0.13 12.3 0.0 12 6.0 0.0 2.2 2 0 0 2 2 2 0 Pab87 octamerisation domain Response_reg PF00072.19 KKK18974.1 - 5.4e-20 71.4 0.0 7.5e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain PQ-loop PF04193.9 KKK18975.1 - 6e-18 64.1 1.0 6e-18 64.1 0.7 3.3 3 1 0 3 3 3 1 PQ loop repeat Vpu PF00558.14 KKK18975.1 - 0.078 12.5 3.4 0.18 11.3 0.2 2.4 2 0 0 2 2 2 0 Vpu protein UL2 PF08196.6 KKK18975.1 - 0.33 10.7 1.7 18 5.1 1.2 2.7 1 1 0 1 1 1 0 UL2 protein SH3_1 PF00018.23 KKK18976.1 - 4.9e-10 38.6 0.1 9.5e-10 37.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK18976.1 - 9.1e-07 28.2 0.0 2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KKK18976.1 - 1.4e-05 24.5 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Herpes_LMP1 PF05297.6 KKK18976.1 - 4.5e-05 22.5 3.4 0.00019 20.5 0.1 2.1 2 0 0 2 2 2 1 Herpesvirus latent membrane protein 1 (LMP1) DUF2069 PF09842.4 KKK18976.1 - 0.037 13.9 2.4 1.1 9.2 0.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) Bot1p PF12298.3 KKK18977.1 - 6.3e-57 192.2 3.1 6.3e-57 192.2 2.1 2.1 1 1 1 2 2 2 1 Eukaryotic mitochondrial regulator protein R3H PF01424.17 KKK19014.1 - 2.4e-11 43.1 0.0 5.4e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 R3H domain SUZ-C PF12901.2 KKK19014.1 - 5.9e-07 28.9 5.0 2.4e-06 27.0 3.5 2.2 1 0 0 1 1 1 1 SUZ-C motif RRM_6 PF14259.1 KKK19014.1 - 9.3e-07 28.7 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK19014.1 - 5.3e-06 25.9 0.1 9.9e-06 25.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK19014.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KKK19016.1 - 2.3e-06 26.9 0.1 2.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KKK19016.1 - 0.0013 17.8 0.2 0.0018 17.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK19016.1 - 0.026 14.2 0.7 0.28 10.8 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family EcKinase PF02958.15 KKK19016.1 - 0.042 12.9 0.2 2.5 7.1 0.0 2.1 1 1 0 2 2 2 0 Ecdysteroid kinase DAO PF01266.19 KKK19017.1 - 2e-41 142.1 0.1 3.1e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Antimicrobial12 PF08107.6 KKK19017.1 - 0.039 13.5 0.5 0.11 12.0 0.3 1.8 1 0 0 1 1 1 0 Pleurocidin family Thi4 PF01946.12 KKK19017.1 - 0.045 12.8 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KKK19017.1 - 0.12 12.4 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 KKK19018.1 - 3.4e-19 69.0 0.0 6.1e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19018.1 - 0.00026 20.1 0.0 0.00085 18.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Glyco_hydro_28 PF00295.12 KKK19019.1 - 1.9e-109 365.6 18.9 2.1e-109 365.4 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KKK19019.1 - 0.00011 21.9 24.7 0.097 12.4 8.3 3.2 1 1 1 3 3 3 3 Right handed beta helix region dCMP_cyt_deam_1 PF00383.17 KKK19020.1 - 1.4e-10 40.7 0.0 2.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glyco_transf_22 PF03901.12 KKK19021.1 - 8.7e-79 265.4 15.6 1e-78 265.2 10.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.16 KKK19022.1 - 5.4e-108 360.8 0.0 6.7e-108 360.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KKK19022.1 - 0.0019 17.1 0.0 0.0036 16.3 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK19022.1 - 0.0038 16.4 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase CBM_14 PF01607.19 KKK19023.1 - 5.5e-10 39.0 6.0 1e-09 38.1 4.1 1.4 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain FAA_hydrolase PF01557.13 KKK19024.1 - 2.3e-46 157.9 0.0 3.1e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KKK19024.1 - 1.4e-20 73.2 0.0 4.2e-19 68.5 0.0 2.6 3 0 0 3 3 3 1 Fumarylacetoacetase N-terminal MFS_1 PF07690.11 KKK19025.1 - 6.2e-37 127.1 50.0 8.6e-37 126.6 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK19025.1 - 1.8e-08 33.4 35.1 1.6e-07 30.2 24.2 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter SUR7 PF06687.7 KKK19026.1 - 8.4e-19 67.9 3.5 1e-18 67.6 2.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KKK19026.1 - 0.056 13.3 6.3 0.029 14.2 2.7 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4282 PF14110.1 KKK19026.1 - 0.088 13.0 0.4 0.088 13.0 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) Claudin_2 PF13903.1 KKK19026.1 - 0.36 10.5 9.2 0.048 13.3 2.1 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1680 PF07944.7 KKK19027.1 - 1.1e-23 83.3 0.1 2.8e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) 2OG-FeII_Oxy_2 PF13532.1 KKK19027.1 - 4.1e-16 59.3 0.0 7.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenyltrans_1 PF13243.1 KKK19027.1 - 0.0018 18.2 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 Prenyltransferase-like Glyoxalase_2 PF12681.2 KKK19028.1 - 2.4e-06 28.1 0.0 4.8e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KKK19028.1 - 0.043 13.8 0.0 0.085 12.8 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TFIID-31kDa PF02291.10 KKK19042.1 - 7.1e-12 45.2 0.0 4.4e-06 26.4 0.0 2.3 1 1 1 2 2 2 2 Transcription initiation factor IID, 31kD subunit Apt1 PF10351.4 KKK19042.1 - 0.036 12.9 0.6 0.05 12.4 0.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CPSF100_C PF13299.1 KKK19042.1 - 0.22 11.7 3.5 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal FLO_LFY PF01698.11 KKK19042.1 - 6.2 5.5 6.9 5.4 5.7 0.4 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein SP_C-Propep PF08999.5 KKK19043.1 - 0.011 15.2 7.8 0.016 14.6 5.4 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide LRRC37AB_C PF14914.1 KKK19043.1 - 0.081 12.3 0.7 0.095 12.1 0.5 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF912 PF06024.7 KKK19043.1 - 0.1 12.6 0.2 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Foamy_virus_ENV PF03408.9 KKK19043.1 - 0.12 9.8 0.2 0.11 9.9 0.2 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein ASFV_J13L PF05568.6 KKK19043.1 - 0.24 10.9 2.0 0.33 10.4 1.4 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Synaptobrevin PF00957.16 KKK19043.1 - 1.2 8.8 3.4 1.8 8.2 2.4 1.2 1 0 0 1 1 1 0 Synaptobrevin DUF677 PF05055.7 KKK19043.1 - 2.4 6.7 8.2 2.6 6.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Glyco_transf_90 PF05686.7 KKK19044.1 - 2.3e-18 66.0 2.0 1.6e-14 53.4 1.0 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ferric_reduct PF01794.14 KKK19044.1 - 5.7e-08 32.8 3.1 5.8e-08 32.8 0.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component B3_4 PF03483.12 KKK19045.1 - 1.3e-24 86.5 0.1 2.7e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KKK19045.1 - 7e-18 64.2 0.0 1.8e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.17 KKK19046.1 - 4.5e-42 138.3 16.4 0.0029 17.5 0.1 13.2 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 KKK19046.1 - 1.6e-34 118.0 0.1 1.2e-08 35.0 0.0 8.0 2 2 4 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 KKK19046.1 - 6.8e-12 45.6 1.4 0.0021 18.3 0.0 7.3 5 2 3 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KKK19046.1 - 3.3e-11 43.3 3.7 0.14 12.7 0.0 9.2 7 2 3 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KKK19046.1 - 1.6e-06 26.7 5.6 4.1e-05 22.1 0.6 3.7 2 1 1 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.3 KKK19046.1 - 0.0028 17.0 0.8 0.19 11.0 0.1 3.8 3 2 1 4 4 4 1 CLASP N terminal DUF2435 PF10363.4 KKK19046.1 - 0.016 15.0 3.7 3.3 7.6 0.1 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) Arm PF00514.18 KKK19046.1 - 0.11 12.3 3.2 13 5.8 0.0 4.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KKK19046.1 - 0.12 12.2 3.4 2.7 7.8 0.0 3.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Myotub-related PF06602.9 KKK19047.1 - 3.6e-125 417.3 0.0 5.9e-125 416.6 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.15 KKK19047.1 - 6.4e-16 58.3 0.1 1.3e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KKK19047.1 - 1.9e-11 43.3 0.1 3.7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 KH domain Y_phosphatase3 PF13350.1 KKK19047.1 - 0.11 12.6 0.2 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family HECT PF00632.20 KKK19049.1 - 1.2e-84 284.2 0.0 2e-84 283.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 KKK19049.1 - 0.00029 20.6 1.1 0.074 13.1 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 KKK19049.1 - 0.0022 17.7 2.2 2.4 8.1 0.0 5.5 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KKK19049.1 - 0.18 10.0 4.2 0.19 9.9 0.1 2.6 3 0 0 3 3 3 0 Adaptin N terminal region SIS PF01380.17 KKK19050.1 - 3.4e-13 49.3 0.0 2.3e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 KKK19050.1 - 2e-08 34.0 0.1 1e-05 25.2 0.1 2.4 1 1 1 2 2 2 2 SIS domain CTP_transf_2 PF01467.21 KKK19051.1 - 1.1e-28 100.3 0.0 1.3e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Peptidase_C13 PF01650.13 KKK19051.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family VIT1 PF01988.14 KKK19054.1 - 5.9e-57 192.5 5.8 6.9e-57 192.3 4.0 1.1 1 0 0 1 1 1 1 VIT family DNA_pol_alpha_N PF12254.3 KKK19055.1 - 4 7.3 5.8 2.6 7.9 1.4 2.2 2 1 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal APH PF01636.18 KKK19056.1 - 0.0064 16.2 0.2 0.0081 15.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family VPS9 PF02204.13 KKK19057.1 - 6.5e-31 106.4 0.0 1.1e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KKK19057.1 - 1.6e-09 37.0 0.3 2.5e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.16 KKK19058.1 - 1.7e-52 178.4 0.0 2.2e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KKK19058.1 - 2.1e-07 30.7 0.0 2e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KKK19058.1 - 2.3e-06 27.5 0.0 0.0002 21.3 0.0 3.0 4 0 0 4 4 4 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KKK19058.1 - 1.3e-05 24.5 0.0 2.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein bZIP_1 PF00170.16 KKK19059.1 - 4e-08 33.1 9.3 7.8e-08 32.1 6.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK19059.1 - 7.9e-06 25.5 10.2 7.9e-06 25.5 7.1 2.3 3 0 0 3 3 3 1 Basic region leucine zipper TPR_14 PF13428.1 KKK19059.1 - 0.0093 16.5 1.1 0.022 15.3 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat KilA-N PF04383.8 KKK19060.1 - 0.00016 21.2 0.0 0.0029 17.2 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Metallophos PF00149.23 KKK19069.1 - 2.6e-38 131.4 0.0 3.8e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KKK19069.1 - 5.7e-31 106.3 0.3 1.3e-30 105.2 0.2 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 KKK19069.1 - 2.4e-20 71.9 5.0 2.2e-16 59.2 0.6 2.6 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KKK19069.1 - 1.1e-10 40.5 4.6 0.00019 20.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK19069.1 - 3.3e-09 35.9 6.6 0.0042 16.8 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK19069.1 - 7.8e-08 32.7 2.7 0.0044 17.6 0.2 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK19069.1 - 0.0011 19.2 0.6 0.36 11.1 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KKK19069.1 - 0.0026 17.5 0.4 0.012 15.5 0.3 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK19069.1 - 0.015 15.8 2.6 2.6 8.9 0.3 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KKK19069.1 - 0.015 15.3 0.7 0.19 11.8 0.3 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KKK19069.1 - 0.019 15.4 1.0 3 8.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KKK19069.1 - 0.019 14.8 3.9 0.11 12.4 0.7 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Aminotran_3 PF00202.16 KKK19070.1 - 2.7e-96 322.3 0.0 3.5e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.8 KKK19071.1 - 1.4e-32 111.3 0.1 1.7e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF2293 PF10056.4 KKK19072.1 - 6e-31 106.2 0.1 6e-31 106.2 0.0 2.3 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2293) Adap_comp_sub PF00928.16 KKK19075.1 - 2.5e-90 302.1 0.0 3.1e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KKK19075.1 - 5.7e-06 26.1 2.8 9e-06 25.4 2.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KKK19075.1 - 0.11 11.6 0.0 0.51 9.4 0.0 1.9 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain RecU PF03838.9 KKK19075.1 - 0.12 11.9 0.4 3.2 7.2 0.2 2.2 2 0 0 2 2 2 0 Recombination protein U NAD_binding_5 PF07994.7 KKK19082.1 - 2.8e-111 371.7 0.2 3.3e-111 371.4 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KKK19082.1 - 3.9e-46 155.4 0.3 7e-46 154.6 0.2 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF1459 PF07312.6 KKK19082.1 - 0.059 13.2 0.5 0.35 10.7 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1459) DHHA2 PF02833.9 KKK19082.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 DHHA2 domain LIM PF00412.17 KKK19083.1 - 2.8e-18 65.7 16.9 1.9e-11 43.8 1.8 2.8 3 1 0 3 3 3 2 LIM domain Cytochrom_c3_2 PF14537.1 KKK19083.1 - 1.3 9.4 6.8 4.3 7.7 4.7 2.0 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 KKK19083.1 - 6.3 6.5 11.6 1.3 8.7 4.6 2.2 1 1 1 2 2 2 0 Cytochrome c7 TspO_MBR PF03073.10 KKK19084.1 - 1.3e-42 144.7 10.4 1.3e-42 144.7 7.2 2.5 3 0 0 3 3 3 1 TspO/MBR family MIP PF00230.15 KKK19084.1 - 2.1e-26 92.7 9.6 4.1e-26 91.8 6.7 1.4 1 0 0 1 1 1 1 Major intrinsic protein PIP5K PF01504.13 KKK19085.1 - 1.6e-86 289.5 0.1 2e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase zf-CCHC_6 PF15288.1 KKK19085.1 - 0.081 12.6 1.2 0.2 11.3 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle SRA1 PF07304.6 KKK19094.1 - 5e-14 52.3 0.0 5.4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 KKK19094.1 - 0.016 15.0 0.1 0.36 10.6 0.0 2.0 1 1 1 2 2 2 0 Prp18 domain DUF313 PF03754.8 KKK19094.1 - 0.046 13.6 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF313) EutQ PF06249.7 KKK19103.1 - 5.5e-12 45.4 0.0 6.8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 KKK19103.1 - 4.5e-08 32.3 0.1 6.4e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 KKK19103.1 - 1.5e-05 24.4 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KKK19103.1 - 0.0047 16.5 0.0 0.0054 16.3 0.0 1.1 1 0 0 1 1 1 1 Cupin Pirin PF02678.11 KKK19103.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Pirin SH3BGR PF04908.10 KKK19103.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Fungal_trans_2 PF11951.3 KKK19104.1 - 1.1e-61 208.6 1.0 1.4e-61 208.1 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1687 PF07955.6 KKK19105.1 - 8.9e-09 35.4 0.0 4.5e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.20 KKK19106.1 - 5.1e-56 189.6 0.0 3.4e-55 186.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19106.1 - 3.3e-27 95.1 0.1 1.8e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KKK19106.1 - 3.1e-07 30.7 0.1 6.6e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KKK19106.1 - 0.00055 18.9 0.1 0.0039 16.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KKK19106.1 - 0.00087 19.0 0.0 0.13 11.9 0.0 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK19106.1 - 0.07 12.1 0.4 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3237 PF11578.3 KKK19107.1 - 3.1e-21 75.2 0.0 1.8e-20 72.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 KKK19107.1 - 1.8e-07 30.7 2.9 0.0075 16.0 0.3 2.6 2 0 0 2 2 2 2 BED zinc finger Tmemb_55A PF09788.4 KKK19107.1 - 0.0086 15.2 5.6 0.049 12.7 0.5 2.3 2 0 0 2 2 2 2 Transmembrane protein 55A zf-C2H2_2 PF12756.2 KKK19107.1 - 0.018 15.1 5.2 1 9.4 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Herpes_capsid PF06112.6 KKK19107.1 - 0.052 13.5 14.4 15 5.6 9.9 2.9 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein TFIIA PF03153.8 KKK19107.1 - 0.42 10.4 5.5 0.54 10.0 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asn_synthase PF00733.16 KKK19108.1 - 5.8e-46 157.0 0.0 8.9e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KKK19108.1 - 4.6e-37 126.5 0.0 7.9e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KKK19108.1 - 2.5e-32 111.6 0.0 4.3e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KKK19108.1 - 0.00056 19.1 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 KKK19108.1 - 0.035 12.7 0.0 0.22 10.1 0.0 1.9 1 1 1 2 2 2 0 Glutamine amidotransferases class-II ICL PF00463.16 KKK19109.1 - 5.9e-188 625.3 0.0 7.2e-188 625.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KKK19109.1 - 1.9e-10 40.3 0.1 9.2e-10 38.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 KKK19109.1 - 0.048 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Phage-A118_gp45 PF10653.4 KKK19110.1 - 0.096 12.5 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein gp45 of Bacteriophage A118 DUF1077 PF06417.7 KKK19111.1 - 9.9e-53 176.7 2.1 1.2e-52 176.4 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Aminotran_5 PF00266.14 KKK19112.1 - 3.1e-08 32.7 0.0 1.5e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KKK19112.1 - 0.0017 17.4 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CWC25 PF12542.3 KKK19113.1 - 4.4e-22 78.3 0.0 4.4e-22 78.3 0.0 3.9 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.4 KKK19113.1 - 3.6e-14 52.5 9.3 3.6e-14 52.5 6.4 4.6 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Adaptin_N PF01602.15 KKK19114.1 - 1.3e-127 426.2 10.7 1.7e-127 425.9 7.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KKK19114.1 - 1.1e-16 61.1 4.3 2.4e-16 60.0 0.1 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KKK19114.1 - 6.3e-16 58.4 3.0 2.9e-09 37.0 0.0 4.7 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 KKK19114.1 - 6e-07 29.0 8.9 0.0069 16.3 0.0 6.1 9 0 0 9 9 9 2 HEAT repeat Atx10homo_assoc PF09759.4 KKK19114.1 - 1.7e-06 27.6 0.1 0.082 12.6 0.0 3.8 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 KKK19114.1 - 0.00097 19.5 5.7 0.99 9.9 0.0 6.0 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.18 KKK19114.1 - 0.0049 16.6 5.2 0.57 10.0 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KKK19114.1 - 0.011 15.1 1.7 1.1 8.5 0.0 3.1 4 0 0 4 4 4 0 CLASP N terminal Paf67 PF10255.4 KKK19115.1 - 1.1e-158 528.3 0.0 1.3e-158 528.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 DUF1254 PF06863.7 KKK19115.1 - 0.055 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) TPR_2 PF07719.12 KKK19115.1 - 0.063 13.2 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fe-S_biosyn PF01521.15 KKK19116.1 - 4.7e-11 42.6 0.0 1.2e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis RHINO PF15319.1 KKK19116.1 - 0.4 10.4 4.7 0.58 9.9 3.2 1.2 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Ribosomal_S11 PF00411.14 KKK19117.1 - 8.6e-41 138.5 0.4 1.1e-40 138.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 AAR2 PF05282.6 KKK19118.1 - 5.4e-102 341.4 0.0 7e-102 341.0 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein PP2C_C PF07830.8 KKK19118.1 - 0.11 12.6 0.1 0.47 10.6 0.1 2.0 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Aminotran_4 PF01063.14 KKK19119.1 - 1.1e-25 90.4 0.0 1.6e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Fungal_trans PF04082.13 KKK19120.1 - 1.7e-19 69.7 0.5 3.2e-19 68.8 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PDH PF02153.12 KKK19121.1 - 1.7e-13 50.0 0.0 2.4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 KKK19121.1 - 7.4e-07 29.5 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KKK19121.1 - 3.3e-06 27.0 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KKK19121.1 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KKK19121.1 - 0.005 16.2 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KKK19121.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KKK19121.1 - 0.049 13.6 0.1 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DUF4168 PF13767.1 KKK19121.1 - 0.072 13.7 0.1 23 5.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) IlvN PF07991.7 KKK19121.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AMP-binding PF00501.23 KKK19122.1 - 2.1e-78 263.6 0.0 2.9e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AA_permease PF00324.16 KKK19123.1 - 5.9e-132 440.3 51.6 7.1e-132 440.1 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK19123.1 - 9.3e-35 119.9 58.1 1.2e-34 119.6 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease WW PF00397.21 KKK19124.1 - 7e-10 38.5 1.0 1.7e-09 37.3 0.7 1.7 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.5 KKK19125.1 - 1.1e-21 76.9 0.0 2.4e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) Mito_carr PF00153.22 KKK19126.1 - 5.3e-49 163.8 1.4 5.6e-18 64.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 KKK19126.1 - 0.0025 17.5 0.2 0.01 15.6 0.1 2.0 2 0 0 2 2 2 1 UcrQ family AphA_like PF14557.1 KKK19126.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.6 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator Ssl1 PF04056.9 KKK19127.1 - 3.7e-77 258.2 0.0 5.4e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KKK19127.1 - 4.4e-18 65.0 9.0 4.4e-18 65.0 6.3 2.5 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 KKK19127.1 - 5.4e-12 46.1 0.0 7.9e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KKK19127.1 - 0.00034 20.3 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain PsiE PF06146.7 KKK19127.1 - 0.0031 17.7 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphate-starvation-inducible E Ras PF00071.17 KKK19128.1 - 3e-23 81.9 0.3 3.6e-23 81.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Peptidase_M1 PF01433.15 KKK19129.1 - 5.2e-132 440.6 0.6 1.2e-131 439.3 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 KKK19129.1 - 3.2e-73 246.7 6.7 5.2e-73 246.1 4.7 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KKK19129.1 - 4.1e-22 78.5 1.8 8.2e-22 77.6 1.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily WD40 PF00400.27 KKK19130.1 - 7e-15 54.2 8.3 4.4e-06 26.3 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Raptor_N PF14538.1 KKK19130.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain RRM_1 PF00076.17 KKK19136.1 - 1.7e-15 56.3 0.0 3.1e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK19136.1 - 1.3e-12 47.5 0.0 2.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK19136.1 - 9.8e-06 25.3 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L32e PF01655.13 KKK19137.1 - 6.8e-49 164.5 0.8 1.4e-48 163.5 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.17 KKK19137.1 - 6.5e-17 62.1 0.0 1.7e-16 60.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KKK19137.1 - 0.0031 17.2 0.0 0.0077 16.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sec2p PF06428.6 KKK19138.1 - 6.5e-08 32.3 12.1 6.5e-08 32.3 8.4 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Not3 PF04065.10 KKK19138.1 - 0.16 11.2 10.0 2.8 7.1 4.6 2.2 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Jnk-SapK_ap_N PF09744.4 KKK19138.1 - 0.16 11.9 14.5 0.69 9.8 6.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.16 KKK19138.1 - 0.3 11.0 14.2 0.24 11.3 0.4 3.1 2 1 1 3 3 3 0 bZIP transcription factor DUF444 PF04285.7 KKK19138.1 - 0.31 9.6 11.3 0.036 12.7 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF444) Vac_Fusion PF02346.11 KKK19138.1 - 1.5 8.2 7.5 5.2 6.5 1.9 2.6 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF2360 PF10152.4 KKK19138.1 - 5 7.3 14.3 0.17 12.1 4.1 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) MFS_1 PF07690.11 KKK19139.1 - 1.1e-44 152.6 43.5 5.1e-35 120.8 12.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KKK19139.1 - 4.5e-08 31.6 18.0 1.1e-06 27.1 3.5 2.8 2 2 1 3 3 3 2 Transmembrane secretion effector OATP PF03137.15 KKK19139.1 - 0.0062 14.6 5.5 0.0073 14.4 1.5 2.5 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family NAD4L PF06235.6 KKK19139.1 - 0.011 15.4 0.3 0.011 15.4 0.2 2.6 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) BT1 PF03092.11 KKK19139.1 - 0.19 10.3 14.4 0.017 13.8 0.5 3.2 1 1 2 3 3 3 0 BT1 family CTD_bind PF04818.8 KKK19168.1 - 0.0005 20.2 0.0 0.0017 18.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. MIS13 PF08202.6 KKK19170.1 - 1.3e-45 155.8 7.1 3.3e-44 151.1 5.0 2.2 1 1 0 1 1 1 1 Mis12-Mtw1 protein family TSNR_N PF04705.7 KKK19170.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus L_lactis_ph-MCP PF06673.6 KKK19170.1 - 0.035 12.9 0.2 0.058 12.1 0.1 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein TSC22 PF01166.13 KKK19170.1 - 0.15 12.0 4.4 0.061 13.2 1.0 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 KKK19170.1 - 0.17 11.3 3.4 0.42 10.1 2.4 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.1 KKK19170.1 - 0.41 11.1 4.5 0.28 11.6 0.7 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HTH_29 PF13551.1 KKK19170.1 - 5.1 7.2 9.8 1.2 9.3 1.0 3.7 3 0 0 3 3 3 0 Winged helix-turn helix DUF1212 PF06738.7 KKK19171.1 - 1.3e-55 187.8 19.7 2e-53 180.7 0.1 2.8 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KKK19171.1 - 9.4e-30 103.2 13.5 9.4e-30 103.2 9.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Synaphin PF05835.7 KKK19173.1 - 8.2 6.5 7.9 11 6.1 5.1 1.7 1 1 0 1 1 1 0 Synaphin protein Helicase_C_3 PF13625.1 KKK19174.1 - 1.8e-27 95.6 0.0 5.7e-27 94.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK19174.1 - 4.4e-14 52.7 0.0 9.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK19174.1 - 2.1e-12 46.7 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KKK19174.1 - 3.2e-12 45.8 0.1 5.3e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KKK19174.1 - 1.3e-06 28.0 0.0 2.9e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.1 KKK19174.1 - 0.0024 16.6 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Sugar_tr PF00083.19 KKK19175.1 - 2.1e-82 277.0 12.3 2.5e-82 276.8 8.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK19175.1 - 2.1e-33 115.4 25.2 2.8e-33 115.1 17.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK19175.1 - 0.0014 16.9 1.5 0.0014 16.9 1.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PS_Dcarbxylase PF02666.10 KKK19176.1 - 1.2e-51 174.9 0.0 1.7e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KKK19176.1 - 3.6e-23 81.1 0.1 2.5e-13 49.6 0.1 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 KKK19176.1 - 0.0014 18.7 0.3 0.0042 17.1 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KKK19176.1 - 0.0093 15.2 0.1 0.029 13.6 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KKK19176.1 - 0.018 14.8 0.0 0.081 12.8 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 KKK19176.1 - 0.047 13.0 0.0 0.14 11.5 0.0 1.9 1 0 0 1 1 1 0 EF hand Hydrophobin PF01185.13 KKK19177.1 - 0.0049 17.2 7.3 0.0097 16.3 5.0 1.5 1 0 0 1 1 1 1 Fungal hydrophobin IBN_N PF03810.14 KKK19194.1 - 2.6e-13 49.6 1.6 7.5e-13 48.2 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KKK19194.1 - 0.0032 17.3 4.0 0.014 15.3 0.0 3.9 4 1 1 5 5 5 1 Exportin 1-like protein AAA PF00004.24 KKK19208.1 - 2.4e-14 53.6 0.1 6.5e-13 49.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK19208.1 - 0.02 14.6 0.0 0.054 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) BCS1_N PF08740.6 KKK19208.1 - 0.026 14.1 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 BCS1 N terminal AAA_25 PF13481.1 KKK19208.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KKK19208.1 - 0.031 15.0 0.0 0.099 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KKK19208.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC Velvet PF11754.3 KKK19209.1 - 2.8e-66 223.0 0.0 3.6e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Ribosomal_L12 PF00542.14 KKK19210.1 - 6.1e-19 67.7 10.7 1.2e-17 63.6 5.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain HisG_C PF08029.6 KKK19210.1 - 0.013 15.3 0.2 0.041 13.8 0.1 1.9 1 1 0 1 1 1 0 HisG, C-terminal domain FliG_N PF14842.1 KKK19210.1 - 0.022 14.8 1.0 0.032 14.3 0.2 1.6 2 0 0 2 2 2 0 FliG N-terminal domain GHMP_kinases_C PF08544.8 KKK19210.1 - 0.033 14.3 3.8 3.4 7.9 0.9 3.2 2 2 0 2 2 2 0 GHMP kinases C terminal Ribosomal_60s PF00428.14 KKK19210.1 - 0.89 10.0 9.7 0.054 13.9 1.0 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF1682 PF07946.9 KKK19211.1 - 3.3e-113 377.7 2.4 3.9e-113 377.5 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) 7TMR-HDED PF07697.6 KKK19211.1 - 0.034 13.8 3.5 0.052 13.2 2.4 1.2 1 0 0 1 1 1 0 7TM-HD extracellular NAD_binding_10 PF13460.1 KKK19212.1 - 2.6e-11 43.8 0.0 4.1e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK19212.1 - 4.3e-07 29.6 0.0 9.1e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK19212.1 - 6.7e-06 25.0 0.0 1.5e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KKK19212.1 - 1.8e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KKK19212.1 - 0.0083 15.0 0.0 0.81 8.5 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein SYF2 PF08231.7 KKK19213.1 - 9.2e-55 184.9 14.7 9.2e-55 184.9 10.2 2.0 2 0 0 2 2 2 1 SYF2 splicing factor gag_pre-integrs PF13976.1 KKK19214.1 - 0.095 12.3 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain IDO PF01231.13 KKK19215.1 - 1.5e-162 540.9 0.0 1.7e-162 540.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase YEATS PF03366.11 KKK19216.1 - 3.5e-36 122.7 1.4 5.3e-36 122.2 1.0 1.3 1 0 0 1 1 1 1 YEATS family DUF334 PF03904.8 KKK19216.1 - 0.23 10.7 1.4 0.46 9.7 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) Aminotran_5 PF00266.14 KKK19218.1 - 2.1e-07 30.0 0.0 1.4e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KKK19218.1 - 0.023 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PX PF00787.19 KKK19220.1 - 2.2e-13 50.0 0.0 4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.23 KKK19220.1 - 7e-12 44.5 0.0 2.2e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 SH3 domain PB1 PF00564.19 KKK19220.1 - 1.7e-09 37.2 0.6 3.4e-09 36.2 0.4 1.5 1 0 0 1 1 1 1 PB1 domain SH3_9 PF14604.1 KKK19220.1 - 1.3e-05 24.7 0.1 2.8e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KKK19220.1 - 0.074 12.5 0.0 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain Pex14_N PF04695.8 KKK19220.1 - 2.1 8.3 10.7 3.4 7.7 1.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AFG1_ATPase PF03969.11 KKK19221.1 - 4.4e-82 275.7 0.0 3.2e-62 210.4 0.0 3.2 3 0 0 3 3 3 3 AFG1-like ATPase Cation_efflux PF01545.16 KKK19221.1 - 2.9e-62 210.3 1.9 4.9e-62 209.5 1.3 1.2 1 0 0 1 1 1 1 Cation efflux family AAA_16 PF13191.1 KKK19221.1 - 0.0011 19.0 0.0 0.44 10.5 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA PF00004.24 KKK19221.1 - 0.017 15.2 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) BPD_transp_2 PF02653.11 KKK19221.1 - 0.026 13.5 0.4 0.054 12.4 0.3 1.5 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component AAA_5 PF07728.9 KKK19221.1 - 0.047 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KKK19221.1 - 0.07 13.2 0.0 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KKK19221.1 - 0.094 12.8 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Bac_DnaA PF00308.13 KKK19221.1 - 0.14 11.7 0.1 5.2 6.6 0.0 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein Rhodanese PF00581.15 KKK19222.1 - 8.7e-12 45.3 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Peripla_BP_6 PF13458.1 KKK19222.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein RabGAP-TBC PF00566.13 KKK19223.1 - 4.1e-25 88.5 0.2 5.8e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CaKB PF03185.10 KKK19223.1 - 0.033 13.5 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit GTP_EFTU PF00009.22 KKK19224.1 - 6.4e-33 113.7 0.0 2.7e-32 111.7 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KKK19224.1 - 2.4e-18 66.0 0.1 6.7e-18 64.5 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KKK19224.1 - 7.4e-12 45.2 3.9 9.7e-10 38.4 0.0 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KKK19224.1 - 6.1e-06 26.1 0.0 2.7e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KKK19224.1 - 0.0063 16.0 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 KKK19224.1 - 0.0064 16.1 0.1 0.023 14.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KKK19224.1 - 0.0086 16.5 0.5 0.068 13.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein MMS1_N PF10433.4 KKK19225.1 - 6.8e-148 492.9 0.0 1.5e-146 488.5 0.0 2.2 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KKK19225.1 - 6.9e-10 38.5 0.0 4.4e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.1 KKK19225.1 - 0.18 12.1 0.1 7.6 6.9 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain TrkH PF02386.11 KKK19226.1 - 2.1e-119 398.2 18.6 3.1e-118 394.4 6.2 2.1 2 0 0 2 2 2 2 Cation transport protein PH PF00169.24 KKK19227.1 - 0.13 12.4 1.3 0.3 11.3 0.9 1.5 1 0 0 1 1 1 0 PH domain Gti1_Pac2 PF09729.4 KKK19227.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.8 3 1 0 3 3 3 0 Gti1/Pac2 family RmlD_sub_bind PF04321.12 KKK19228.1 - 1.6e-54 184.7 0.0 2.1e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KKK19228.1 - 3.9e-21 75.5 0.0 6.3e-21 74.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK19228.1 - 5.6e-12 45.1 0.2 3.6e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KKK19228.1 - 2.5e-09 36.4 0.2 2.5e-07 29.9 0.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KKK19228.1 - 2.6e-09 36.1 0.0 1.5e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KKK19228.1 - 3.1e-05 24.0 0.0 4.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KKK19228.1 - 0.00016 21.6 0.2 0.04 13.8 0.1 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK19228.1 - 0.0041 16.8 0.2 2.3 7.8 0.0 2.9 3 0 0 3 3 3 2 KR domain Glyco_trans_2_3 PF13632.1 KKK19229.1 - 5.6e-35 120.8 6.5 5.6e-35 120.8 4.5 2.1 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK19229.1 - 0.00013 21.8 0.0 0.00069 19.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Tir_receptor_C PF07489.6 KKK19229.1 - 0.084 12.6 0.2 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Glycos_transf_2 PF00535.21 KKK19229.1 - 0.15 11.7 0.0 0.48 10.0 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 F-box PF00646.28 KKK19230.1 - 0.027 14.1 1.7 0.13 11.9 1.2 2.2 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KKK19230.1 - 0.39 10.4 7.4 0.075 12.7 1.1 2.7 3 0 0 3 3 3 0 F-box-like Sulf_transp PF04143.9 KKK19231.1 - 8.4e-17 60.9 22.0 1.7e-11 43.9 2.4 4.4 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 KKK19231.1 - 2.1e-09 36.9 0.9 2.1e-09 36.9 0.6 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF4341) FR47 PF08445.5 KKK19232.1 - 0.035 13.8 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein p450 PF00067.17 KKK19233.1 - 0.00039 19.0 0.3 0.00081 18.0 0.2 1.5 1 0 0 1 1 1 1 Cytochrome P450 GAS PF13851.1 KKK19233.1 - 0.0066 15.6 15.0 0.12 11.6 6.7 2.5 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 KKK19233.1 - 0.0088 16.0 12.8 0.059 13.3 3.2 3.1 1 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 KKK19233.1 - 0.0094 15.1 1.1 0.015 14.5 0.7 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Paralemmin PF03285.10 KKK19233.1 - 0.027 13.9 3.0 0.048 13.1 2.1 1.4 1 0 0 1 1 1 0 Paralemmin Filament PF00038.16 KKK19233.1 - 0.11 11.9 25.8 0.023 14.1 5.4 3.4 3 1 1 4 4 4 0 Intermediate filament protein COG5 PF10392.4 KKK19233.1 - 0.11 12.4 8.1 0.019 14.9 2.7 2.0 2 0 0 2 2 1 0 Golgi transport complex subunit 5 V-SNARE PF05008.10 KKK19233.1 - 0.29 11.3 9.4 0.022 14.8 2.9 2.0 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus FlaC_arch PF05377.6 KKK19233.1 - 0.31 10.9 3.7 0.38 10.6 0.4 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IFT57 PF10498.4 KKK19233.1 - 0.5 9.0 11.3 0.94 8.1 7.8 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4140 PF13600.1 KKK19233.1 - 0.75 10.2 9.7 9.3 6.7 0.2 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Med4 PF10018.4 KKK19233.1 - 0.93 8.8 12.2 6.2 6.1 7.9 2.5 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Mnd1 PF03962.10 KKK19233.1 - 0.97 9.0 14.5 0.026 14.1 3.0 2.4 2 1 0 2 2 2 0 Mnd1 family DivIC PF04977.10 KKK19233.1 - 1 8.8 5.9 5.6 6.5 0.9 3.0 2 1 0 2 2 2 0 Septum formation initiator Laminin_II PF06009.7 KKK19233.1 - 1.1 9.0 8.1 0.7 9.6 1.8 2.6 3 0 0 3 3 3 0 Laminin Domain II Prominin PF05478.6 KKK19233.1 - 1.3 6.4 3.7 2.2 5.7 2.6 1.3 1 0 0 1 1 1 0 Prominin DUF3461 PF11944.3 KKK19233.1 - 1.6 8.6 7.0 0.46 10.3 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Fib_alpha PF08702.5 KKK19233.1 - 1.8 8.6 9.3 1.7 8.7 3.9 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HlyD PF00529.15 KKK19233.1 - 3.2 6.9 10.5 5 6.3 6.6 1.8 1 1 1 2 2 2 0 HlyD family secretion protein DUF1664 PF07889.7 KKK19233.1 - 3.8 7.3 5.7 1.4 8.7 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.6 KKK19233.1 - 5 6.3 8.8 2.6 7.2 3.6 2.1 2 1 0 2 2 2 0 Allexivirus 40kDa protein BLOC1_2 PF10046.4 KKK19233.1 - 5.3 7.2 8.7 1.2 9.2 2.3 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HlyD_2 PF12700.2 KKK19233.1 - 6.4 5.8 6.9 1.3 8.0 1.7 1.8 2 0 0 2 2 2 0 HlyD family secretion protein DUF3450 PF11932.3 KKK19233.1 - 7.7 5.6 13.3 9 5.4 4.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Peptidase_M28 PF04389.12 KKK19234.1 - 5.9e-32 110.8 0.0 8.3e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Sec7 PF01369.15 KKK19235.1 - 2.3e-40 138.3 0.0 4e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KKK19235.1 - 2.5e-08 34.1 0.2 5.4e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KKK19235.1 - 0.0004 20.5 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Zip PF02535.17 KKK19236.1 - 2.9e-23 82.3 10.3 1.1e-22 80.4 7.2 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1399 PF07173.7 KKK19250.1 - 1.7e-20 73.6 3.9 8.2e-17 61.7 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) Pea-VEAacid PF08111.6 KKK19250.1 - 0.64 10.2 3.8 6.9 7.0 0.2 2.7 2 0 0 2 2 2 0 Pea-VEAacid family Fungal_trans PF04082.13 KKK19251.1 - 1.2e-13 50.5 1.2 1.9e-13 49.8 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19251.1 - 1.2e-06 28.3 10.4 2.7e-06 27.2 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 KKK19252.1 - 0.0032 17.1 0.2 0.0093 15.6 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK19252.1 - 0.018 14.6 0.4 0.038 13.6 0.3 1.6 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.13 KKK19253.1 - 3.2e-19 68.8 0.1 9.8e-19 67.2 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19253.1 - 1.3e-06 28.1 7.0 3e-06 27.0 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc PF00614.17 KKK19255.1 - 7.9e-15 54.1 0.5 1.6e-07 30.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KKK19255.1 - 1.3e-11 44.3 0.0 1.2e-06 28.3 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KKK19255.1 - 7.3e-08 32.1 0.3 2.8e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 PX domain MR_MLE_C PF13378.1 KKK19256.1 - 8.5e-20 70.7 0.0 1.7e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KKK19256.1 - 1.1e-11 45.0 0.0 2.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KKK19256.1 - 1.2e-10 41.4 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.13 KKK19257.1 - 9.1e-24 83.7 0.1 1.3e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 KKK19258.1 - 1.9e-32 112.4 0.0 3.2e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19258.1 - 1.2e-23 83.5 0.0 2e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Spc7 PF08317.6 KKK19258.1 - 0.17 10.5 0.1 0.25 9.9 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fungal_trans PF04082.13 KKK19260.1 - 5.9e-22 77.7 0.1 1.2e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19260.1 - 1.4e-10 40.8 11.1 2.8e-10 39.9 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBFD_NFYB_HMF PF00808.18 KKK19261.1 - 2.9e-29 100.8 0.9 4.1e-29 100.4 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK19261.1 - 1.1e-06 28.6 0.1 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KKK19261.1 - 0.00075 19.2 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KKK19261.1 - 0.0014 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KKK19261.1 - 0.049 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Gly-zipper_OmpA PF13436.1 KKK19261.1 - 7.4 6.2 16.7 0.1 12.2 4.6 2.5 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Fungal_trans PF04082.13 KKK19262.1 - 7.2e-21 74.2 0.1 3.3e-20 72.0 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19262.1 - 5.3e-10 39.0 10.2 8.4e-10 38.4 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NRDE-2 PF08424.5 KKK19262.1 - 3.1 6.6 9.7 0.14 11.0 2.3 2.0 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference Abhydrolase_6 PF12697.2 KKK19263.1 - 3.3e-27 95.8 0.5 7e-27 94.7 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK19263.1 - 8.9e-16 58.1 0.0 1.1e-14 54.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK19263.1 - 3.8e-12 46.1 0.0 6.1e-11 42.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KKK19263.1 - 2.6e-06 26.6 0.0 4.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 KKK19263.1 - 6.9e-06 25.6 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 KKK19263.1 - 0.0025 17.4 0.0 0.05 13.1 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.8 KKK19263.1 - 0.0071 15.9 0.1 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KKK19263.1 - 0.0087 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 KKK19263.1 - 0.013 14.9 0.0 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KKK19263.1 - 0.018 15.2 0.2 0.08 13.1 0.1 2.0 1 1 0 1 1 1 0 Thioesterase domain DUF2305 PF10230.4 KKK19263.1 - 0.045 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KKK19263.1 - 0.049 13.2 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Hydrolase_4 PF12146.3 KKK19263.1 - 0.068 13.0 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase p450 PF00067.17 KKK19264.1 - 1.3e-56 192.0 0.0 1.8e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MarB PF13999.1 KKK19265.1 - 0.25 10.9 1.2 0.6 9.7 0.1 2.0 2 0 0 2 2 2 0 MarB protein Spo7 PF03907.8 KKK19266.1 - 1.1e-64 217.8 0.0 1.7e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein TatD_DNase PF01026.16 KKK19267.1 - 4.7e-33 114.4 0.0 1e-32 113.3 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase DAD PF02109.11 KKK19268.1 - 3.9e-28 97.7 2.4 1.6e-17 63.5 0.3 3.0 2 1 0 2 2 2 2 DAD family HA2 PF04408.18 KKK19269.1 - 1.6e-23 82.6 0.0 5.4e-23 80.9 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KKK19269.1 - 2.9e-22 78.6 0.0 1.5e-20 73.1 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KKK19269.1 - 1.9e-14 53.2 0.0 5.5e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK19269.1 - 2.7e-07 30.2 0.0 1.7e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK19269.1 - 6.4e-05 23.0 0.1 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KKK19269.1 - 0.0005 19.0 0.0 0.0022 16.9 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.10 KKK19269.1 - 0.00056 19.7 0.3 0.38 10.5 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit SRP54 PF00448.17 KKK19269.1 - 0.0024 17.3 0.2 0.0069 15.8 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain DUF2075 PF09848.4 KKK19269.1 - 0.0026 16.8 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KKK19269.1 - 0.005 15.9 0.0 0.0098 15.0 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 KKK19269.1 - 0.0064 16.3 0.2 0.045 13.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 KKK19269.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Arch_ATPase PF01637.13 KKK19269.1 - 0.031 13.9 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 KKK19269.1 - 0.071 13.4 0.1 0.27 11.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 KKK19269.1 - 0.083 13.1 0.1 0.3 11.3 0.0 2.0 2 0 0 2 2 1 0 ABC transporter NB-ARC PF00931.17 KKK19269.1 - 0.11 11.2 0.1 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 KKK19269.1 - 0.13 11.8 1.1 0.8 9.3 0.8 2.2 1 1 0 1 1 1 0 NACHT domain Prefoldin_2 PF01920.15 KKK19270.1 - 4.1e-26 90.8 6.6 4.9e-26 90.5 4.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tho2 PF11262.3 KKK19270.1 - 0.0023 17.0 1.7 0.013 14.6 1.1 1.9 1 1 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 KaiC PF06745.8 KKK19270.1 - 0.0046 16.0 0.2 0.26 10.3 0.0 2.0 1 1 1 2 2 2 1 KaiC GAS PF13851.1 KKK19270.1 - 0.0088 15.2 7.9 0.013 14.7 5.5 1.2 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding STAT_alpha PF01017.15 KKK19270.1 - 0.024 14.3 6.0 0.032 13.9 4.1 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain IncA PF04156.9 KKK19270.1 - 0.035 13.7 8.5 0.057 13.0 5.9 1.3 1 1 0 1 1 1 0 IncA protein Prefoldin PF02996.12 KKK19270.1 - 0.035 13.7 7.2 0.37 10.4 0.1 2.2 1 1 0 2 2 2 0 Prefoldin subunit DUF641 PF04859.7 KKK19270.1 - 0.051 13.3 3.5 0.17 11.6 0.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DASH_Dad3 PF08656.5 KKK19270.1 - 0.083 12.5 4.7 0.11 12.2 0.7 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 p25-alpha PF05517.7 KKK19270.1 - 0.088 13.0 1.0 0.69 10.1 0.1 2.0 2 0 0 2 2 2 0 p25-alpha DUF2659 PF10858.3 KKK19270.1 - 0.13 11.6 2.3 2.7 7.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2659) DUF4200 PF13863.1 KKK19270.1 - 0.17 11.8 7.6 0.11 12.4 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 KKK19270.1 - 0.64 9.8 6.8 0.31 10.8 0.9 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KKK19270.1 - 0.7 9.6 8.5 1.7 8.3 0.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cytochrom_B562 PF07361.6 KKK19270.1 - 0.74 10.2 5.4 0.51 10.7 1.5 1.9 2 0 0 2 2 2 0 Cytochrome b562 AAA_13 PF13166.1 KKK19270.1 - 0.88 7.9 5.2 1 7.7 3.6 1.0 1 0 0 1 1 1 0 AAA domain Spc24 PF08286.6 KKK19270.1 - 2.6 7.7 7.5 2 8.1 0.9 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF342 PF03961.8 KKK19270.1 - 3.4 5.9 6.0 7 4.9 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 KKK19270.1 - 6.9 6.5 11.1 0.34 10.7 1.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ribosomal_60s PF00428.14 KKK19271.1 - 0.014 15.7 4.0 0.014 15.7 2.8 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein PPR_3 PF13812.1 KKK19272.1 - 4.4e-20 70.2 12.8 0.013 15.7 0.0 11.6 13 0 0 13 13 13 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 KKK19272.1 - 5.7e-19 67.8 4.3 1.2e-07 31.5 0.1 7.3 8 1 1 9 9 9 4 PPR repeat family PPR PF01535.15 KKK19272.1 - 1e-13 50.2 4.5 0.0079 16.1 0.1 8.9 9 0 0 9 9 9 3 PPR repeat TPR_14 PF13428.1 KKK19272.1 - 9.1e-06 25.8 7.0 8.6 7.3 0.0 8.0 8 1 1 9 9 9 2 Tetratricopeptide repeat PPR_1 PF12854.2 KKK19272.1 - 2.6e-05 23.6 0.2 3.2 7.3 0.0 4.9 4 0 0 4 4 4 1 PPR repeat MCM PF00493.18 KKK19273.1 - 5.6e-128 426.3 0.2 8.5e-128 425.8 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KKK19273.1 - 8.6e-18 64.9 0.0 2.2e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KKK19273.1 - 3.9e-06 26.1 0.0 4.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KKK19273.1 - 0.0069 15.9 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Metallophos PF00149.23 KKK19281.1 - 3.7e-41 140.7 0.2 4.8e-41 140.3 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Memo PF01875.12 KKK19283.1 - 1.9e-64 217.1 0.0 2.3e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein WD40 PF00400.27 KKK19284.1 - 0.11 12.4 4.0 0.28 11.1 0.3 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat PBP1_TM PF14812.1 KKK19284.1 - 0.2 11.9 32.1 0.64 10.3 5.6 4.6 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 KKK19284.1 - 4 7.7 24.2 6.3 7.0 0.2 3.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Med3 PF11593.3 KKK19284.1 - 6.5 5.8 12.8 2.8 7.0 0.4 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal LSM PF01423.17 KKK19285.1 - 9.3e-06 25.1 0.0 1.2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KKK19285.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Pkinase PF00069.20 KKK19286.1 - 1.4e-29 103.0 0.0 2e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19286.1 - 3.4e-09 36.1 0.0 0.00061 18.9 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3435 PF11917.3 KKK19286.1 - 0.00079 18.2 0.0 0.001 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) AA_permease PF00324.16 KKK19287.1 - 1.5e-135 452.2 37.6 1.7e-135 452.1 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK19287.1 - 8.8e-36 123.3 41.0 1.1e-35 122.9 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aldose_epim PF01263.15 KKK19288.1 - 2.9e-40 138.2 0.0 3.3e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase zf-RING_2 PF13639.1 KKK19289.1 - 1.1e-16 60.3 4.5 2e-16 59.5 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KKK19289.1 - 1.6e-10 40.7 4.3 2.8e-10 40.0 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK19289.1 - 2.9e-09 36.4 2.8 5.2e-09 35.6 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK19289.1 - 7.7e-09 35.1 3.2 1.3e-08 34.3 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KKK19289.1 - 1.1e-07 31.8 4.9 3.2e-07 30.3 3.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KKK19289.1 - 1.6e-07 30.8 2.1 2.8e-07 30.1 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KKK19289.1 - 2.5e-06 27.0 2.0 6.9e-06 25.6 1.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KKK19289.1 - 0.00013 21.7 3.8 0.00013 21.7 2.6 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 KKK19289.1 - 0.00055 19.2 0.3 0.022 13.9 0.0 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger RINGv PF12906.2 KKK19289.1 - 0.0012 18.8 1.1 0.0029 17.6 0.8 1.7 1 1 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KKK19289.1 - 0.0012 18.7 3.2 0.0046 16.8 2.2 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 KKK19289.1 - 0.0013 18.2 4.0 0.0022 17.5 2.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.24 KKK19289.1 - 0.0026 17.3 2.4 0.0056 16.3 1.7 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KKK19289.1 - 0.0075 15.9 4.5 0.0081 15.8 0.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 APC_CDC26 PF10471.4 KKK19289.1 - 0.0078 16.9 4.6 0.017 15.8 3.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Chordopox_A13L PF05961.6 KKK19289.1 - 0.013 15.3 0.4 0.98 9.4 0.2 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein zf-Apc11 PF12861.2 KKK19289.1 - 0.021 14.6 4.4 0.021 14.6 3.1 2.4 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KKK19289.1 - 0.035 13.6 1.0 0.065 12.7 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 KKK19289.1 - 0.041 13.8 2.6 0.11 12.5 1.8 1.8 1 1 0 1 1 1 0 RING-like domain YfhO PF09586.5 KKK19289.1 - 0.075 11.0 0.0 0.095 10.7 0.0 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO TMEM154 PF15102.1 KKK19289.1 - 0.17 11.6 1.5 18 5.0 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family MFS_Mycoplasma PF07672.8 KKK19289.1 - 0.73 8.9 2.4 0.51 9.4 0.2 1.6 1 1 1 2 2 2 0 Mycoplasma MFS transporter DUF4175 PF13779.1 KKK19289.1 - 1 6.9 9.3 1.4 6.5 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med3 PF11593.3 KKK19289.1 - 2 7.5 10.9 2.8 7.1 7.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BAF1_ABF1 PF04684.8 KKK19289.1 - 9.4 4.9 15.9 13 4.5 11.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ABC_membrane PF00664.18 KKK19290.1 - 3.6e-63 213.5 25.5 2e-38 132.4 5.2 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KKK19290.1 - 1.4e-56 190.5 0.0 1.1e-28 100.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KKK19290.1 - 7.4e-19 67.8 0.9 1.4e-07 31.0 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain Polysacc_synt_4 PF04669.8 KKK19290.1 - 1.1e-16 60.8 1.1 3.1e-16 59.2 0.7 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis AAA_21 PF13304.1 KKK19290.1 - 3.6e-12 46.8 4.6 0.0083 16.1 0.5 4.6 4 1 0 4 4 3 3 AAA domain AAA_29 PF13555.1 KKK19290.1 - 2e-08 33.6 2.4 0.0031 17.0 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KKK19290.1 - 3.9e-08 32.9 0.0 0.093 12.1 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KKK19290.1 - 2.3e-07 31.6 0.5 0.031 15.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK19290.1 - 8.3e-07 29.2 4.1 0.0047 17.0 0.0 4.6 3 2 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KKK19290.1 - 5.6e-06 26.6 1.0 0.19 12.0 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 KKK19290.1 - 2.8e-05 23.7 4.3 0.097 12.0 0.3 4.0 4 0 0 4 4 4 2 AAA-like domain AAA_16 PF13191.1 KKK19290.1 - 2.9e-05 24.1 0.3 0.085 12.8 0.2 3.2 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KKK19290.1 - 5.1e-05 22.5 0.1 0.39 9.8 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 KKK19290.1 - 0.00011 21.0 2.6 0.15 10.6 0.0 3.7 4 0 0 4 4 4 1 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 KKK19290.1 - 0.00094 18.7 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KKK19290.1 - 0.001 19.0 0.7 0.86 9.5 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 KKK19290.1 - 0.0019 18.0 0.0 3.6 7.5 0.0 3.0 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KKK19290.1 - 0.0036 17.1 0.0 4 7.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KKK19290.1 - 0.0058 16.4 5.3 0.091 12.5 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_5 PF07728.9 KKK19290.1 - 0.015 14.9 0.2 5.3 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 KKK19290.1 - 0.018 13.5 3.9 6.1 5.1 0.1 3.5 3 0 0 3 3 3 0 AAA domain KaiC PF06745.8 KKK19290.1 - 0.019 14.0 8.1 4.3 6.3 0.3 3.8 4 0 0 4 4 4 0 KaiC Miro PF08477.8 KKK19290.1 - 0.02 15.3 0.1 15 6.1 0.0 3.7 3 0 0 3 3 3 0 Miro-like protein AAA_15 PF13175.1 KKK19290.1 - 0.026 13.5 8.2 0.12 11.3 0.0 4.2 5 0 0 5 5 5 0 AAA ATPase domain MobB PF03205.9 KKK19290.1 - 0.027 14.1 1.3 3.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KKK19290.1 - 0.033 13.8 0.3 13 5.4 0.4 2.8 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 KKK19290.1 - 0.034 14.4 6.1 0.95 9.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.15 KKK19290.1 - 0.042 13.5 0.3 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF3987 PF13148.1 KKK19290.1 - 0.061 11.8 1.5 4 5.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Sigma54_activat PF00158.21 KKK19290.1 - 0.081 12.3 0.0 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KKK19290.1 - 0.13 12.4 0.0 26 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DLH PF01738.13 KKK19291.1 - 4.5e-20 71.8 0.0 1.5e-19 70.1 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK19291.1 - 2.2e-05 24.2 0.0 4.4e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK19291.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Gal_mutarotas_2 PF13802.1 KKK19291.1 - 0.054 13.3 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Galactose mutarotase-like Rif1_N PF12231.3 KKK19292.1 - 1.4e-145 484.9 0.1 2.4e-145 484.1 0.0 1.4 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.4 KKK19293.1 - 1e-134 449.7 0.0 1.3e-134 449.3 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Pkinase PF00069.20 KKK19294.1 - 1.1e-40 139.4 0.0 4.6e-40 137.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19294.1 - 2.1e-28 99.1 0.0 2.9e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK19294.1 - 0.0018 17.3 0.0 0.0043 16.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KKK19294.1 - 0.0044 16.7 2.5 0.038 13.7 0.1 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK19294.1 - 0.013 14.5 0.0 0.051 12.6 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KKK19294.1 - 0.23 10.2 0.0 0.57 8.9 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Sulfotransfer_3 PF13469.1 KKK19295.1 - 0.083 13.8 2.2 0.16 12.9 1.5 1.6 1 1 0 1 1 1 0 Sulfotransferase family DAHP_synth_2 PF01474.11 KKK19297.1 - 2.1e-44 151.5 0.0 2.4e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF912 PF06024.7 KKK19298.1 - 0.02 14.9 0.1 0.37 10.8 0.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1180 PF06679.7 KKK19298.1 - 1.7 8.5 0.0 1.7 8.5 0.0 3.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1180) MFS_1 PF07690.11 KKK19299.1 - 2.5e-26 92.2 20.1 4.1e-26 91.5 13.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cep57_CLD_2 PF14197.1 KKK19299.1 - 3.7e-20 71.6 10.4 3.7e-20 71.6 7.2 3.9 4 0 0 4 4 4 1 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.8 KKK19299.1 - 6.7e-13 48.3 2.4 3.9e-08 33.1 0.0 4.5 4 1 1 5 5 5 2 Centrosome microtubule-binding domain of Cep57 MFS_3 PF05977.8 KKK19299.1 - 0.012 13.7 1.5 0.022 12.9 1.0 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector DUF3508 PF12018.3 KKK19299.1 - 0.098 11.6 6.9 0.32 9.9 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3508) FAT PF02259.18 KKK19300.1 - 0.0021 17.1 1.2 0.0044 16.0 0.4 1.8 1 1 1 2 2 2 1 FAT domain TPR_16 PF13432.1 KKK19300.1 - 0.017 15.7 4.5 1 10.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK19300.1 - 0.027 14.7 0.1 5.3 7.4 0.0 3.4 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK19300.1 - 0.042 14.4 6.4 42 5.1 0.0 5.4 3 2 2 5 5 5 0 Tetratricopeptide repeat HAT PF02184.11 KKK19300.1 - 9.1 6.1 10.4 10 5.9 0.0 4.2 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat MAT1 PF06391.8 KKK19301.1 - 2.6e-35 121.8 14.7 3.2e-35 121.5 10.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KKK19301.1 - 0.00026 20.5 4.6 0.00083 18.9 3.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK19301.1 - 0.0013 18.6 5.9 0.003 17.5 4.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK19301.1 - 0.0015 18.1 6.0 0.0029 17.2 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK19301.1 - 0.0046 16.7 5.7 0.01 15.6 3.9 1.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 KKK19301.1 - 0.01 15.3 5.0 0.14 11.7 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KKK19301.1 - 0.023 14.4 9.4 0.25 11.1 7.0 2.1 1 1 1 2 2 2 0 zinc-RING finger domain VID27 PF08553.5 KKK19301.1 - 0.35 9.0 5.5 0.47 8.6 3.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein APG6 PF04111.7 KKK19301.1 - 3 6.8 8.3 4.9 6.1 5.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3835 PF12927.2 KKK19302.1 - 2.3e-24 86.1 5.7 6.5e-23 81.5 0.2 4.7 4 2 0 4 4 4 2 Domain of unknown function (DUF3835) Prefoldin_3 PF13758.1 KKK19302.1 - 3.9e-17 61.8 0.8 6.4e-14 51.5 0.0 2.8 1 1 1 2 2 2 2 Prefoldin subunit NGP1NT PF08153.7 KKK19303.1 - 5.6e-48 162.1 0.0 9e-48 161.5 0.0 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KKK19303.1 - 1.2e-18 67.0 0.1 1e-14 54.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK19303.1 - 0.00026 20.3 0.0 0.00087 18.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KKK19303.1 - 0.00044 20.1 0.1 0.11 12.3 0.0 3.3 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 KKK19303.1 - 0.0029 16.8 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF258 PF03193.11 KKK19303.1 - 0.0077 15.4 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SusD-like_3 PF14322.1 KKK19303.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane DUF4282 PF14110.1 KKK19305.1 - 0.0068 16.5 12.1 0.023 14.8 4.5 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4282) DUF2244 PF10003.4 KKK19305.1 - 0.04 13.2 8.6 0.17 11.2 0.1 2.5 2 1 0 2 2 2 0 Integral membrane protein (DUF2244) PLDc_N PF13396.1 KKK19305.1 - 1.6 8.4 10.1 0.74 9.5 0.6 3.2 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal HemY_N PF07219.8 KKK19305.1 - 3 7.4 8.0 1.5 8.3 0.9 2.3 2 0 0 2 2 2 0 HemY protein N-terminus DEAD PF00270.24 KKK19306.1 - 5e-41 140.0 0.0 3.4e-40 137.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK19306.1 - 9.1e-26 89.5 0.1 2.3e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 KKK19306.1 - 0.0021 18.3 3.4 0.0077 16.5 2.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) DUF3334 PF11813.3 KKK19306.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) But2 PF09792.4 KKK19307.1 - 7.1e-60 200.9 2.1 7.1e-60 200.9 1.5 2.9 3 1 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain PAT1 PF09770.4 KKK19307.1 - 2.2 6.4 10.6 2.7 6.1 7.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAP2 PF01569.16 KKK19308.1 - 2.1e-26 92.0 0.2 4.1e-26 91.1 0.1 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF898 PF05987.8 KKK19308.1 - 0.42 9.4 2.0 0.39 9.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) AMMECR1 PF01871.12 KKK19310.1 - 2.6e-40 137.3 0.0 5e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 AMMECR1 Pkinase PF00069.20 KKK19311.1 - 1.6e-69 233.9 0.0 2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19311.1 - 5e-30 104.4 0.0 6.4e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK19311.1 - 7.9e-07 28.3 0.0 1.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK19311.1 - 0.00023 20.9 0.1 0.0004 20.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK19311.1 - 0.00024 20.2 0.0 0.00044 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KKK19311.1 - 0.0097 15.2 0.0 0.029 13.7 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Microtub_assoc PF07989.6 KKK19312.1 - 4.2e-27 93.7 5.6 4.2e-27 93.7 3.9 10.6 7 2 5 14 14 14 1 Microtubule associated PACT_coil_coil PF10495.4 KKK19312.1 - 5e-27 93.6 1.3 1.6e-26 92.0 0.9 2.0 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Bacillus_HBL PF05791.6 KKK19312.1 - 0.00012 21.5 10.1 0.00012 21.5 7.0 7.1 4 2 2 6 6 6 1 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.3 KKK19312.1 - 0.00054 19.7 13.2 0.00054 19.7 9.1 14.2 9 4 4 14 14 14 3 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 KKK19312.1 - 0.0079 16.0 13.3 0.0079 16.0 9.2 11.5 2 2 9 11 11 11 3 Tropomyosin like SGT1 PF07093.6 KKK19313.1 - 8.3e-150 499.9 22.9 4.3e-148 494.3 15.9 2.0 1 1 0 1 1 1 1 SGT1 protein eIF-1a PF01176.14 KKK19313.1 - 0.035 13.5 0.1 0.91 8.9 0.1 2.7 3 0 0 3 3 3 0 Translation initiation factor 1A / IF-1 SH3_9 PF14604.1 KKK19313.1 - 0.1 12.1 0.2 1.1 8.9 0.0 2.6 2 1 1 3 3 3 0 Variant SH3 domain Prefoldin_2 PF01920.15 KKK19314.1 - 7.1e-19 67.5 13.0 7.7e-19 67.4 6.9 1.9 2 0 0 2 2 2 1 Prefoldin subunit Atg14 PF10186.4 KKK19314.1 - 0.03 13.2 5.5 0.039 12.8 3.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_3 PF13758.1 KKK19314.1 - 0.056 13.2 4.5 0.14 11.9 3.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 KKK19314.1 - 0.084 12.4 15.8 0.51 9.8 7.8 2.1 1 1 1 2 2 2 0 IncA protein ERp29 PF07749.7 KKK19314.1 - 0.19 12.3 2.8 0.43 11.2 1.9 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DivIC PF04977.10 KKK19314.1 - 0.24 10.9 15.1 0.12 11.8 0.8 3.1 3 0 0 3 3 3 0 Septum formation initiator DUF1319 PF07028.6 KKK19314.1 - 1 9.5 7.5 1.3 9.2 3.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) COG2 PF06148.6 KKK19314.1 - 1.9 8.3 6.8 1.4 8.7 0.9 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin PF02996.12 KKK19314.1 - 2.3 7.8 11.8 0.11 12.0 2.1 2.7 2 1 1 3 3 3 0 Prefoldin subunit Spc7 PF08317.6 KKK19314.1 - 2.6 6.6 11.1 2.4 6.7 6.7 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Sugarporin_N PF11471.3 KKK19314.1 - 2.8 7.6 9.7 0.53 9.9 0.1 3.0 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Tropomyosin_1 PF12718.2 KKK19314.1 - 3.5 7.4 11.6 1.7 8.5 2.0 2.7 3 0 0 3 3 3 0 Tropomyosin like DUF3571 PF12095.3 KKK19314.1 - 3.9 7.7 5.6 3.3 8.0 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3571) Spc24 PF08286.6 KKK19314.1 - 9.5 5.9 13.3 1.2 8.8 1.6 2.6 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Vps4_C PF09336.5 KKK19315.1 - 6.9e-29 99.5 0.0 4e-28 97.1 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA PF00004.24 KKK19315.1 - 1.7e-27 96.2 0.0 1.4e-26 93.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 KKK19315.1 - 1.2e-23 82.7 1.8 1.2e-23 82.7 1.2 2.4 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 KKK19315.1 - 4.9e-06 27.3 0.1 2.7e-05 24.9 0.0 2.3 3 1 0 3 3 1 1 AAA domain IstB_IS21 PF01695.12 KKK19315.1 - 6.3e-06 25.7 0.0 1.6e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KKK19315.1 - 1.4e-05 25.2 0.1 0.0045 17.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KKK19315.1 - 1.5e-05 24.1 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KKK19315.1 - 1.9e-05 24.3 0.0 0.00011 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KKK19315.1 - 4e-05 22.6 0.0 0.0006 18.8 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 KKK19315.1 - 4e-05 23.6 0.0 0.00016 21.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 KKK19315.1 - 7.7e-05 21.5 0.0 0.00013 20.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KKK19315.1 - 8.4e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KKK19315.1 - 0.00013 21.8 0.0 0.00031 20.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KKK19315.1 - 0.0002 20.8 0.2 0.14 11.5 0.1 3.3 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 KKK19315.1 - 0.00096 19.3 0.0 0.0079 16.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KKK19315.1 - 0.0022 18.2 0.1 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KKK19315.1 - 0.0027 17.6 0.0 0.022 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) USP8_dimer PF08969.6 KKK19315.1 - 0.0063 16.4 2.4 0.015 15.2 1.6 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain Arch_ATPase PF01637.13 KKK19315.1 - 0.0088 15.7 0.2 0.24 11.0 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 KKK19315.1 - 0.0089 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KKK19315.1 - 0.014 14.5 0.1 0.099 11.7 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin Bac_DnaA PF00308.13 KKK19315.1 - 0.015 14.9 0.0 0.078 12.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein Mg_chelatase PF01078.16 KKK19315.1 - 0.023 13.8 0.0 0.07 12.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KKK19315.1 - 0.024 14.2 0.0 0.55 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.1 KKK19315.1 - 0.027 14.0 0.1 0.092 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 KKK19315.1 - 0.047 13.3 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Guanylate_kin PF00625.16 KKK19315.1 - 0.059 12.8 0.0 0.17 11.2 0.0 1.8 1 0 0 1 1 1 0 Guanylate kinase Parvo_NS1 PF01057.12 KKK19315.1 - 0.088 11.6 0.0 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 KKK19315.1 - 0.09 13.0 0.0 0.45 10.8 0.0 2.3 2 1 1 3 3 2 0 ABC transporter ResIII PF04851.10 KKK19315.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KKK19315.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 KKK19315.1 - 0.13 11.0 0.0 0.73 8.5 0.0 2.0 2 0 0 2 2 2 0 MCM2/3/5 family Sigma54_activ_2 PF14532.1 KKK19315.1 - 0.14 12.2 0.1 0.55 10.2 0.0 2.0 2 1 0 2 2 1 0 Sigma-54 interaction domain DUF4398 PF14346.1 KKK19315.1 - 0.24 11.4 1.9 0.46 10.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Med9 PF07544.8 KKK19316.1 - 1.5e-25 88.7 0.0 1.9e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.10 KKK19316.1 - 0.029 13.8 0.2 0.12 11.9 0.0 1.9 1 1 1 2 2 2 0 Septum formation initiator Med21 PF11221.3 KKK19316.1 - 0.034 14.1 0.1 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Fmp27_WPPW PF10359.4 KKK19316.1 - 0.05 12.0 0.4 0.059 11.7 0.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain MscS_porin PF12795.2 KKK19316.1 - 0.062 12.6 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain SNARE PF05739.14 KKK19316.1 - 0.063 12.9 0.2 0.14 11.8 0.1 1.6 2 0 0 2 2 2 0 SNARE domain ArgK PF03308.11 KKK19316.1 - 0.065 12.0 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 ArgK protein FlaC_arch PF05377.6 KKK19316.1 - 0.08 12.8 0.2 1.7 8.6 0.0 2.1 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.4 KKK19316.1 - 0.083 12.7 0.3 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Metalloenzyme PF01676.13 KKK19317.1 - 4.8e-71 239.0 0.1 5.5e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KKK19317.1 - 2.5e-70 236.3 0.0 3.3e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 KKK19317.1 - 2.3e-06 27.1 0.0 5.2e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KKK19317.1 - 0.0015 17.8 0.0 0.014 14.5 0.0 2.3 2 1 1 3 3 3 1 Sulfatase Alk_phosphatase PF00245.15 KKK19317.1 - 0.02 13.5 0.0 0.14 10.8 0.0 1.9 2 0 0 2 2 2 0 Alkaline phosphatase AP_endonuc_2 PF01261.19 KKK19317.1 - 0.022 14.0 0.0 0.048 12.9 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel 4HBT_3 PF13622.1 KKK19318.1 - 5.9e-39 134.3 0.1 7.1e-39 134.0 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Myb_DNA-bind_3 PF12776.2 KKK19319.1 - 0.14 12.8 0.5 0.3 11.7 0.2 1.7 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-C2H2 PF00096.21 KKK19320.1 - 4.6e-07 29.7 9.7 0.00029 21.0 0.3 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 KKK19320.1 - 8.5e-06 24.8 0.0 1.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.3 KKK19320.1 - 0.00029 20.8 2.5 0.58 10.3 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KKK19320.1 - 0.00034 20.7 5.4 0.00034 20.7 3.7 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK19320.1 - 0.023 15.0 16.0 0.081 13.2 0.5 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 KKK19320.1 - 0.031 14.4 1.0 1.7 8.9 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KKK19320.1 - 0.48 10.4 8.8 0.35 10.8 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.11 KKK19321.1 - 1.7e-40 138.8 14.9 2.7e-40 138.1 10.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK19321.1 - 8.7e-14 50.9 21.8 2.9e-11 42.6 3.8 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KKK19321.1 - 3.2e-08 32.2 4.2 7e-07 27.8 0.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF2275 PF10039.4 KKK19321.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) AA_permease PF00324.16 KKK19322.1 - 2.3e-96 323.0 37.7 2.8e-96 322.7 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK19322.1 - 2.5e-23 82.3 40.0 3.4e-23 81.8 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KKK19322.1 - 0.068 12.9 15.7 0.067 12.9 0.9 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) Raffinose_syn PF05691.7 KKK19323.1 - 2.4e-50 170.9 0.1 2.7e-43 147.5 0.0 2.6 2 1 1 3 3 3 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KKK19323.1 - 0.00036 19.3 0.5 0.00059 18.6 0.4 1.2 1 0 0 1 1 1 1 Melibiase Alpha-amylase PF00128.19 KKK19324.1 - 2.9e-16 59.7 0.5 4.2e-15 55.9 0.3 2.7 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KKK19324.1 - 4.8e-15 55.7 0.1 8.5e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KKK19324.1 - 1e-06 28.9 0.0 2.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KKK19324.1 - 4.2e-06 26.2 0.0 7.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ADH_zinc_N PF00107.21 KKK19325.1 - 1.1e-27 96.1 0.2 1.6e-27 95.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK19325.1 - 1.6e-15 58.0 0.0 3.9e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK19325.1 - 1.7e-12 47.0 0.1 5.6e-12 45.3 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KKK19325.1 - 0.00045 19.8 0.1 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KKK19325.1 - 0.0026 17.7 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KKK19325.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 KKK19325.1 - 0.038 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Alpha-amylase PF00128.19 KKK19326.1 - 1.4e-22 80.5 0.4 2.9e-21 76.1 0.3 2.3 1 1 1 2 2 2 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KKK19326.1 - 7.3e-07 27.3 0.0 0.0086 13.8 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Alpha-amylase PF00128.19 KKK19327.1 - 2.4e-34 119.1 0.3 3.1e-34 118.7 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KKK19327.1 - 9.3e-29 99.3 0.0 2.4e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DNMT1-RFD PF12047.3 KKK19328.1 - 0.075 12.7 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain TruB_N PF01509.13 KKK19329.1 - 4.6e-47 159.9 0.0 3e-46 157.2 0.0 2.2 3 0 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) vMSA PF00695.14 KKK19329.1 - 0.78 8.8 5.3 1.2 8.2 3.7 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Ebp2 PF05890.7 KKK19330.1 - 1.1e-96 323.3 12.4 1.1e-96 323.3 8.6 2.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Spore_coat_CotO PF14153.1 KKK19330.1 - 3.8 6.9 31.2 0.27 10.6 13.6 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Astro_capsid PF03115.9 KKK19330.1 - 4.8 5.3 13.4 9.7 4.3 9.3 1.5 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Daxx PF03344.10 KKK19330.1 - 4.8 5.5 40.7 9.4 4.5 28.2 1.5 1 1 0 1 1 1 0 Daxx Family DUF1455 PF07306.6 KKK19338.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Chlorosome_CsmC PF11098.3 KKK19338.1 - 0.14 11.8 2.2 0.35 10.5 1.5 1.6 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF1279 PF06916.8 KKK19339.1 - 9.2e-13 48.3 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) JmjC PF02373.17 KKK19340.1 - 8.9e-37 125.8 0.8 8.9e-37 125.8 0.5 2.7 4 0 0 4 4 4 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 KKK19340.1 - 7.1e-18 64.5 4.4 1.6e-17 63.4 3.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KKK19340.1 - 9.7e-18 64.1 5.0 1.9e-17 63.2 3.5 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.12 KKK19340.1 - 1.1e-15 56.7 0.3 2.9e-15 55.5 0.2 1.8 1 0 0 1 1 1 1 jmjN domain TPR_11 PF13414.1 KKK19343.1 - 0.0015 18.1 0.2 0.012 15.2 0.0 2.4 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.1 KKK19343.1 - 0.1 12.8 0.1 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase_4 PF13669.1 KKK19344.1 - 4.2e-06 26.7 0.1 7.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 KKK19344.1 - 1.2e-05 25.2 0.0 0.00045 20.1 0.0 2.1 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_2 PF12681.2 KKK19344.1 - 0.00012 22.6 0.0 0.00022 21.7 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KKK19344.1 - 0.0024 17.8 0.1 0.0046 16.9 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KKK19344.1 - 0.0038 17.1 0.1 0.03 14.2 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain p450 PF00067.17 KKK19345.1 - 2e-60 204.6 0.0 2.7e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SGL PF08450.7 KKK19345.1 - 4.5e-30 104.8 0.0 8.5e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KKK19345.1 - 8.1e-05 22.5 0.0 0.00025 20.9 0.0 1.8 1 0 0 1 1 1 1 Arylesterase NHL PF01436.16 KKK19345.1 - 0.018 15.0 3.0 0.31 11.0 0.0 3.0 3 0 0 3 3 3 0 NHL repeat Str_synth PF03088.11 KKK19345.1 - 0.075 13.0 0.0 0.67 10.0 0.0 2.4 2 1 0 2 2 2 0 Strictosidine synthase Arginosuc_synth PF00764.14 KKK19346.1 - 1.4e-156 521.4 0.0 1.6e-156 521.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 KKK19346.1 - 4.3e-05 22.8 0.0 7.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KKK19346.1 - 0.00016 21.2 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KKK19346.1 - 0.014 13.9 0.0 0.022 13.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Zn_clus PF00172.13 KKK19347.1 - 5.1e-06 26.2 7.1 1.1e-05 25.1 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KKK19347.1 - 0.72 10.0 6.8 8.9 6.5 0.8 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Tim17 PF02466.14 KKK19348.1 - 2.7e-34 117.9 7.0 3.3e-34 117.6 4.9 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 KKK19348.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal UPF0126 PF03458.8 KKK19348.1 - 1.3 8.6 6.8 16 5.1 1.1 3.1 1 1 2 4 4 4 0 UPF0126 domain GST_N_3 PF13417.1 KKK19349.1 - 3.1e-09 36.9 0.0 6.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK19349.1 - 1.4e-08 34.6 0.0 3.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KKK19349.1 - 2.5e-07 30.7 0.0 3e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK19349.1 - 3e-06 27.1 0.0 5.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK19349.1 - 0.0008 19.2 0.1 0.0015 18.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HgmA PF04209.8 KKK19351.1 - 7e-192 637.4 0.0 7.9e-192 637.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 KKK19352.1 - 2.9e-47 160.9 0.0 3.8e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KKK19352.1 - 1.9e-24 85.7 0.0 3.8e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAD_binding_3 PF01494.14 KKK19353.1 - 2e-14 53.4 0.0 3.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK19353.1 - 0.0032 16.4 0.3 0.16 10.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KKK19353.1 - 0.033 13.1 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Nucleoporin2 PF04096.9 KKK19354.1 - 3.4e-45 153.3 0.0 7.2e-45 152.2 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KKK19354.1 - 6.6e-22 77.8 226.1 2.1e-09 37.6 34.3 10.2 3 2 6 9 9 9 5 Nucleoporin FG repeat region Tet_res_leader PF08050.7 KKK19354.1 - 0.19 11.3 0.3 0.38 10.4 0.2 1.4 1 0 0 1 1 1 0 Tetracycline resistance leader peptide Prefoldin_2 PF01920.15 KKK19355.1 - 3.3e-23 81.4 3.5 3.6e-23 81.3 2.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit ALIX_LYPXL_bnd PF13949.1 KKK19355.1 - 0.0013 17.7 1.6 0.0013 17.7 1.1 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Nnf1 PF03980.9 KKK19355.1 - 0.0037 17.2 2.4 0.0053 16.7 1.7 1.2 1 0 0 1 1 1 1 Nnf1 Prefoldin PF02996.12 KKK19355.1 - 0.0037 16.8 5.0 0.0068 16.0 0.2 2.1 1 1 1 2 2 2 1 Prefoldin subunit Med30 PF11315.3 KKK19355.1 - 0.021 14.9 0.9 0.026 14.6 0.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 30 TBCA PF02970.11 KKK19355.1 - 0.073 13.1 5.2 0.24 11.5 3.6 1.8 1 1 0 1 1 1 0 Tubulin binding cofactor A Spc7 PF08317.6 KKK19355.1 - 0.086 11.4 1.9 0.12 11.0 1.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PEP-utilisers_N PF05524.8 KKK19355.1 - 0.094 12.5 1.6 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Seryl_tRNA_N PF02403.17 KKK19355.1 - 0.19 11.7 3.3 0.89 9.6 0.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 KKK19355.1 - 0.21 11.4 1.5 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 KKK19355.1 - 0.26 10.8 8.0 3 7.3 1.5 2.2 2 0 0 2 2 2 0 Septum formation initiator GAS PF13851.1 KKK19355.1 - 0.3 10.2 4.2 1.2 8.2 0.5 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 KKK19355.1 - 0.42 10.5 4.0 6.4 6.6 0.0 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PspA_IM30 PF04012.7 KKK19355.1 - 0.49 9.7 5.1 0.26 10.6 0.3 2.0 2 0 0 2 2 2 0 PspA/IM30 family CENP-F_leu_zip PF10473.4 KKK19355.1 - 0.51 10.1 7.6 0.92 9.3 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SbcD_C PF12320.3 KKK19355.1 - 0.9 9.6 6.3 12 5.9 4.4 2.4 1 1 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain DUF3847 PF12958.2 KKK19355.1 - 1.5 8.5 5.1 9.5 6.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) TBPIP PF07106.8 KKK19355.1 - 1.8 8.0 6.5 1.9 8.0 0.2 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1843 PF08898.5 KKK19355.1 - 2.8 8.0 7.0 2.2 8.4 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF4164 PF13747.1 KKK19355.1 - 3.8 7.7 7.9 14 5.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) IncA PF04156.9 KKK19355.1 - 5.2 6.6 10.3 36 3.8 7.1 1.9 1 1 0 1 1 1 0 IncA protein N2227 PF07942.7 KKK19356.1 - 9.8e-91 303.4 0.0 1.2e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KKK19356.1 - 0.00034 20.3 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK19356.1 - 0.041 14.3 0.0 0.19 12.2 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KKK19356.1 - 0.05 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PEP-utilizers PF00391.18 KKK19357.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Fungal_trans PF04082.13 KKK19358.1 - 6.5e-25 87.4 0.1 1.2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19358.1 - 1e-05 25.3 14.2 2.6e-05 24.0 9.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myosin_head PF00063.16 KKK19370.1 - 4.8e-247 821.4 2.7 4.8e-247 821.4 1.8 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) NAP PF00956.13 KKK19370.1 - 2.7e-85 285.3 9.3 2.7e-85 285.3 6.4 3.3 3 1 0 3 3 1 1 Nucleosome assembly protein (NAP) DIL PF01843.14 KKK19370.1 - 1.3e-34 118.2 3.4 3.9e-34 116.6 2.3 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 KKK19370.1 - 9.7e-14 49.6 33.7 6.9e-05 22.1 0.1 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif CENP-B_dimeris PF09026.5 KKK19370.1 - 0.00013 22.1 22.6 0.0014 18.8 6.0 2.8 2 0 0 2 2 2 2 Centromere protein B dimerisation domain AAA_22 PF13401.1 KKK19370.1 - 0.00015 21.9 1.6 0.0031 17.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain IncA PF04156.9 KKK19370.1 - 0.0084 15.7 35.5 0.44 10.1 11.8 3.2 1 1 1 2 2 2 2 IncA protein AAA_16 PF13191.1 KKK19370.1 - 0.02 14.8 1.0 0.16 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain TMP_2 PF06791.8 KKK19370.1 - 0.032 13.8 1.9 0.098 12.2 1.3 1.9 1 0 0 1 1 1 0 Prophage tail length tape measure protein AAA_19 PF13245.1 KKK19370.1 - 0.034 13.8 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 KKK19370.1 - 0.039 13.1 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GAS PF13851.1 KKK19370.1 - 0.057 12.6 36.5 0.011 14.9 9.2 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding zf-C4H2 PF10146.4 KKK19370.1 - 0.35 10.8 11.3 2.7 7.9 7.1 2.8 2 0 0 2 2 2 0 Zinc finger-containing protein DUF3450 PF11932.3 KKK19370.1 - 0.54 9.4 29.1 0.19 10.9 10.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Reo_sigmaC PF04582.7 KKK19370.1 - 1.5 7.9 5.8 2.8 7.0 3.4 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 KKK19370.1 - 1.7 8.6 11.8 0.18 11.7 0.5 4.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) FUSC PF04632.7 KKK19370.1 - 4.5 5.5 7.6 7.5 4.8 5.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ham1p_like PF01725.11 KKK19371.1 - 7e-54 182.0 0.0 7.8e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 KKK19372.1 - 7e-24 84.5 0.1 1.3e-23 83.7 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK19372.1 - 1.9e-12 48.0 0.2 4e-12 47.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KKK19372.1 - 0.0001 22.4 0.0 0.00022 21.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK19372.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KKK19372.1 - 0.002 18.0 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KKK19372.1 - 0.0049 17.0 0.0 0.01 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 KKK19372.1 - 0.0072 16.2 0.0 0.013 15.3 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase Cytidylate_kin2 PF13189.1 KKK19372.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase-like family Stn1_C PF12659.2 KKK19372.1 - 0.0096 15.7 0.0 3.6 7.4 0.0 2.1 2 0 0 2 2 2 2 Telomere capping C-terminal wHTH AAA_14 PF13173.1 KKK19372.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KKK19372.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.5 KKK19372.1 - 0.025 13.8 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 KKK19372.1 - 0.028 13.9 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KKK19372.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.4 KKK19372.1 - 0.056 12.4 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KKK19372.1 - 0.07 12.5 0.0 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KKK19372.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 KKK19372.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AA_kinase PF00696.23 KKK19373.1 - 6e-42 143.8 0.3 9.2e-42 143.2 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 KKK19373.1 - 2e-12 46.4 0.8 2.1e-10 39.9 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 KKK19373.1 - 6e-12 44.7 0.4 1e-09 37.6 0.1 2.9 2 1 0 2 2 2 2 ACT domain Peptidase_C78 PF07910.8 KKK19374.1 - 5.1e-70 235.0 0.0 6.4e-70 234.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Hist_deacetyl PF00850.14 KKK19374.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SseB_C PF14581.1 KKK19374.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 SseB protein C-terminal domain G10 PF01125.12 KKK19375.1 - 4.6e-67 224.0 4.6 5.1e-67 223.9 3.2 1.0 1 0 0 1 1 1 1 G10 protein Fork_head PF00250.13 KKK19376.1 - 1.6e-36 124.2 0.1 2.8e-36 123.4 0.1 1.4 1 0 0 1 1 1 1 Fork head domain UCR_14kD PF02271.11 KKK19378.1 - 2.7e-46 155.6 0.1 3e-46 155.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 KKK19379.1 - 2.4e-68 225.9 0.0 1.3e-23 82.4 0.0 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein Ecm33 PF12454.3 KKK19380.1 - 3.8e-14 52.2 1.1 3.8e-14 52.2 0.8 2.1 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein LRR_5 PF13306.1 KKK19380.1 - 1.2e-07 31.5 0.3 0.0087 15.7 0.1 2.6 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) Recep_L_domain PF01030.19 KKK19380.1 - 0.00026 20.9 4.1 3.1 7.7 0.0 4.4 1 1 4 5 5 5 3 Receptor L domain HhH-GPD PF00730.20 KKK19381.1 - 8.3e-13 48.5 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Anp1 PF03452.9 KKK19382.1 - 8.9e-109 362.8 0.0 1.1e-108 362.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Rootletin PF15035.1 KKK19383.1 - 0.00044 20.2 7.0 0.0007 19.6 4.8 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Med4 PF10018.4 KKK19383.1 - 0.0012 18.3 3.7 0.0012 18.3 2.6 1.8 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Herpes_UL6 PF01763.11 KKK19383.1 - 0.0013 17.0 1.8 0.0017 16.6 1.3 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF3450 PF11932.3 KKK19383.1 - 0.014 14.7 5.6 0.021 14.0 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.2 KKK19383.1 - 0.052 13.3 5.9 0.1 12.4 4.1 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF972 PF06156.8 KKK19383.1 - 0.065 13.5 7.7 0.042 14.2 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 KKK19383.1 - 0.081 12.7 5.8 0.18 11.6 4.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding NTR2 PF15458.1 KKK19383.1 - 0.11 11.7 11.7 0.23 10.6 8.1 1.5 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DivIC PF04977.10 KKK19383.1 - 0.34 10.4 10.0 0.99 8.9 7.0 1.8 1 1 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 KKK19383.1 - 0.4 10.6 7.2 2.2 8.2 5.0 2.2 1 1 0 1 1 1 0 bZIP transcription factor 7tm_7 PF08395.7 KKK19383.1 - 0.45 9.4 1.9 0.72 8.8 1.3 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF904 PF06005.7 KKK19383.1 - 0.58 10.4 11.8 0.4 10.9 6.9 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF904) DUF3886 PF13025.1 KKK19383.1 - 1 9.3 10.1 2.1 8.3 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) IncA PF04156.9 KKK19383.1 - 2.6 7.6 19.9 0.23 11.0 9.9 1.8 1 1 1 2 2 2 0 IncA protein GP41 PF00517.12 KKK19383.1 - 4.2 6.8 11.7 2.5 7.5 6.7 1.6 1 1 1 2 2 2 0 Retroviral envelope protein Capsid_NCLDV PF04451.7 KKK19391.1 - 0.061 12.3 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Cofilin_ADF PF00241.15 KKK19405.1 - 6.3e-17 61.6 0.0 1.2e-08 34.9 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DNA_topoisoIV PF00521.15 KKK19406.1 - 4.8e-96 322.1 6.6 8.3e-79 265.4 1.3 2.6 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KKK19406.1 - 4.7e-34 117.0 0.4 1.3e-33 115.6 0.3 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KKK19406.1 - 1.7e-14 53.5 0.0 8.9e-14 51.2 0.0 2.3 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KKK19406.1 - 6e-11 42.0 0.0 1.5e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RabGAP-TBC PF00566.13 KKK19407.1 - 1.9e-47 161.5 0.7 1.4e-46 158.6 0.0 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Reticulon PF02453.12 KKK19408.1 - 2.4e-37 128.1 4.4 3.2e-37 127.7 3.0 1.1 1 0 0 1 1 1 1 Reticulon ADP_ribosyl_GH PF03747.9 KKK19410.1 - 3.4e-57 194.4 0.2 3.9e-57 194.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Tyrosinase PF00264.15 KKK19411.1 - 3.2e-34 119.0 1.4 4.7e-29 102.1 0.0 2.2 2 0 0 2 2 2 2 Common central domain of tyrosinase Patatin PF01734.17 KKK19413.1 - 3.6e-15 56.4 0.0 8.1e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Fungal_trans PF04082.13 KKK19414.1 - 8.2e-13 47.8 1.0 1.5e-12 46.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19414.1 - 3e-09 36.6 9.1 5.6e-09 35.7 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain INCENP_ARK-bind PF03941.10 KKK19415.1 - 1.8e-18 66.0 0.3 1.8e-18 66.0 0.2 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region PAN_1 PF00024.21 KKK19417.1 - 0.022 14.4 0.8 0.033 13.9 0.6 1.3 1 0 0 1 1 1 0 PAN domain Abhydrolase_6 PF12697.2 KKK19418.1 - 1.1e-22 81.0 3.0 1.5e-22 80.6 2.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK19418.1 - 1e-09 38.3 0.0 1.6e-09 37.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK19418.1 - 6.3e-07 29.1 0.0 3.1e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold ArsB PF02040.10 KKK19419.1 - 1.6e-11 43.8 23.7 4.3e-08 32.5 4.7 2.5 3 0 0 3 3 3 2 Arsenical pump membrane protein Cutinase PF01083.17 KKK19420.1 - 1.9e-43 148.2 6.1 2.4e-43 147.9 4.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KKK19420.1 - 0.00017 21.1 1.0 0.0015 17.9 0.1 2.1 1 1 1 2 2 2 1 PE-PPE domain Abhydrolase_6 PF12697.2 KKK19420.1 - 0.044 13.6 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family NACHT PF05729.7 KKK19423.1 - 4.1e-07 29.8 0.3 1.7e-06 27.8 0.0 2.1 2 1 1 3 3 3 1 NACHT domain RNA_helicase PF00910.17 KKK19423.1 - 0.0065 16.6 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_32 PF13654.1 KKK19423.1 - 0.014 14.0 0.8 3.5 6.1 0.7 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KKK19423.1 - 0.024 13.6 0.2 0.19 10.6 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KKK19423.1 - 0.042 13.2 0.0 0.78 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Syntaxin-6_N PF09177.6 KKK19423.1 - 0.07 13.5 1.1 0.14 12.5 0.7 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal AAA_19 PF13245.1 KKK19423.1 - 0.093 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Nsp1_C PF05064.8 KKK19423.1 - 0.26 10.9 4.3 0.58 9.8 2.8 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region FlxA PF14282.1 KKK19423.1 - 0.33 10.9 4.5 0.48 10.3 3.1 1.3 1 0 0 1 1 1 0 FlxA-like protein RDM PF11002.3 KKK19423.1 - 1.4 8.6 3.7 5.2 6.8 0.1 3.3 3 1 1 4 4 4 0 RFPL defining motif (RDM) GATase_4 PF13230.1 KKK19425.1 - 5.8e-14 51.4 0.0 1.3e-13 50.3 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KKK19425.1 - 9.2e-10 38.5 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KKK19425.1 - 3.3e-07 29.3 0.0 7.6e-05 21.5 0.1 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Pyr_redox_2 PF07992.9 KKK19426.1 - 1.9e-26 93.2 0.0 2.4e-15 56.9 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK19426.1 - 2.5e-12 46.9 0.0 9.4e-11 41.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK19426.1 - 0.002 18.2 0.0 1.4 8.9 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KKK19426.1 - 0.78 10.0 4.5 8.8 6.6 0.0 3.6 3 1 0 3 3 3 0 Putative NAD(P)-binding RRM_1 PF00076.17 KKK19427.1 - 1.2e-40 136.9 0.0 1.5e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK19427.1 - 4.2e-28 97.1 0.0 3.4e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK19427.1 - 6.3e-18 64.3 0.0 8.4e-10 38.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KKK19427.1 - 0.0073 16.0 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Dynamin_N PF00350.18 KKK19428.1 - 9.6e-44 149.1 0.0 1.8e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KKK19428.1 - 1.2e-12 47.2 0.1 4.6e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KKK19428.1 - 0.0016 18.3 0.0 0.0039 17.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK19428.1 - 0.0042 17.5 0.0 0.009 16.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein phiKZ_IP PF12699.2 KKK19428.1 - 0.042 12.7 0.2 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins AAA_21 PF13304.1 KKK19428.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 KKK19430.1 - 9.6e-36 123.3 2.2 1.2e-35 122.9 1.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK19430.1 - 3.7e-10 39.0 19.9 5.6e-10 38.4 13.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KKK19430.1 - 0.76 8.1 11.9 0.02 13.3 3.7 1.6 2 0 0 2 2 2 0 MFS/sugar transport protein KH_1 PF00013.24 KKK19431.1 - 6.2e-40 134.6 7.0 2.3e-15 55.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KKK19431.1 - 9.5e-30 101.7 10.8 2.3e-11 43.0 0.9 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KKK19431.1 - 2e-10 40.0 6.9 0.0012 18.3 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KKK19431.1 - 1.1e-07 31.3 6.9 0.041 13.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KKK19431.1 - 0.00042 20.0 3.7 0.96 9.3 0.0 3.5 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KKK19431.1 - 0.0033 16.8 0.0 0.8 9.1 0.0 3.2 3 0 0 3 3 3 1 dUTPase zf-CCCH PF00642.19 KKK19432.1 - 6.2e-06 25.7 13.7 0.00036 20.1 0.7 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Dor1 PF04124.7 KKK19432.1 - 0.1 11.0 0.3 0.16 10.3 0.2 1.1 1 0 0 1 1 1 0 Dor1-like family Rubrerythrin PF02915.12 KKK19432.1 - 0.47 10.7 2.9 5.4 7.3 2.0 2.1 1 1 0 1 1 1 0 Rubrerythrin ADH_N PF08240.7 KKK19433.1 - 6.2e-28 96.7 1.2 1.3e-27 95.6 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_3 PF13738.1 KKK19433.1 - 2.5e-17 63.6 0.0 8.1e-13 48.8 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 KKK19433.1 - 1.4e-14 53.7 0.0 2.8e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 KKK19433.1 - 4.3e-09 36.5 0.0 0.00038 20.3 0.0 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK19433.1 - 8.1e-05 22.5 2.4 0.0038 17.2 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK19433.1 - 0.00017 21.3 0.0 0.014 15.2 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FMO-like PF00743.14 KKK19433.1 - 0.0026 16.0 0.0 0.031 12.4 0.0 2.6 4 0 0 4 4 4 1 Flavin-binding monooxygenase-like HI0933_like PF03486.9 KKK19433.1 - 0.0041 15.6 1.2 3.8 5.8 0.2 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.22 KKK19433.1 - 0.0079 16.5 0.8 2.4 8.6 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.1 KKK19433.1 - 0.0098 16.7 0.0 0.031 15.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase K_oxygenase PF13434.1 KKK19433.1 - 0.088 11.7 0.0 0.26 10.1 0.0 1.8 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 KKK19433.1 - 0.097 12.6 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KKK19433.1 - 0.25 10.7 0.2 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Transketolase_N PF00456.16 KKK19434.1 - 5.9e-118 393.4 0.0 3.2e-117 391.0 0.0 1.9 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KKK19434.1 - 9.7e-41 139.2 0.1 2.7e-40 137.7 0.1 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KKK19434.1 - 8.8e-08 31.3 0.0 3e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KKK19434.1 - 6.9e-07 28.2 0.0 1.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 KKK19434.1 - 9.4e-07 28.7 0.0 2.3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Rpp20 PF12328.3 KKK19434.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P GMC_oxred_N PF00732.14 KKK19436.1 - 5.5e-61 206.3 0.0 7.5e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK19436.1 - 3.8e-38 131.0 0.1 6.8e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK19436.1 - 4.1e-07 29.1 0.0 0.0087 14.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK19436.1 - 0.00034 19.6 2.0 0.002 17.1 1.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KKK19436.1 - 0.0065 15.4 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KKK19436.1 - 0.011 15.7 0.1 0.042 13.8 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK19436.1 - 0.042 14.2 0.4 13 6.2 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Phosphoesterase PF04185.9 KKK19437.1 - 2.5e-71 240.8 0.1 3.6e-71 240.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoesterase family Pkinase PF00069.20 KKK19438.1 - 0.00011 21.4 0.2 0.098 11.7 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain WaaY PF06176.6 KKK19438.1 - 0.004 16.4 0.0 0.01 15.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KKK19438.1 - 0.0098 15.6 0.0 0.21 11.3 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family MFS_1 PF07690.11 KKK19439.1 - 3.8e-40 137.6 46.3 3.8e-40 137.6 32.1 3.9 3 1 0 3 3 3 1 Major Facilitator Superfamily Xan_ur_permease PF00860.15 KKK19439.1 - 4.4e-19 68.2 30.4 8.1e-14 50.9 10.6 4.5 5 1 1 6 6 6 2 Permease family Abhydrolase_3 PF07859.8 KKK19440.1 - 3.2e-24 85.6 0.1 4.6e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK19440.1 - 1.3e-17 63.4 0.0 1.9e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK19440.1 - 1.7e-05 24.6 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK19440.1 - 0.021 14.0 0.0 0.08 12.1 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Zn_clus PF00172.13 KKK19441.1 - 1.3e-07 31.4 9.1 2.6e-07 30.4 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK19441.1 - 0.00045 19.1 0.0 0.0011 17.8 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.13 KKK19442.1 - 3.1e-05 23.1 10.3 7.9e-05 21.8 7.1 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein NAD_binding_6 PF08030.7 KKK19443.1 - 3.9e-07 30.0 0.0 0.00021 21.2 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KKK19443.1 - 2.6e-06 27.9 0.0 0.049 14.1 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Pantoate_ligase PF02569.10 KKK19443.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Racemase_4 PF13615.1 KKK19443.1 - 0.27 11.4 1.6 4.5 7.5 0.4 2.5 2 1 0 2 2 2 0 Putative alanine racemase Epimerase PF01370.16 KKK19444.1 - 2.4e-09 36.9 0.0 0.00038 19.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK19444.1 - 9.9e-06 24.6 0.0 2.2e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 KKK19444.1 - 3.2e-05 24.2 0.0 6.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KKK19444.1 - 7.1e-05 22.1 0.1 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KKK19444.1 - 0.00072 18.5 0.1 0.41 9.5 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 KKK19444.1 - 0.003 17.5 0.1 0.0068 16.4 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KKK19444.1 - 0.0031 16.5 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DXP_reductoisom PF02670.11 KKK19444.1 - 0.0082 16.6 0.0 0.015 15.8 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.10 KKK19444.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GATA PF00320.22 KKK19445.1 - 4.9e-16 57.7 4.5 9.6e-16 56.8 3.1 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 KKK19445.1 - 4.1e-05 23.3 0.0 0.00037 20.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KKK19445.1 - 6.2e-05 23.3 0.0 0.0002 21.6 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KKK19445.1 - 0.0042 17.1 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 PAS fold Zn-ribbon_8 PF09723.5 KKK19445.1 - 0.1 12.5 0.3 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain 7TM_GPCR_Str PF10326.4 KKK19446.1 - 0.001 18.2 2.3 0.013 14.6 0.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Str Baculo_11_kDa PF06143.6 KKK19446.1 - 0.096 12.0 2.7 4.7 6.6 0.3 3.0 3 0 0 3 3 3 0 Baculovirus 11 kDa family Tetraspannin PF00335.15 KKK19446.1 - 0.57 9.4 3.7 0.78 8.9 0.0 2.3 2 1 0 2 2 2 0 Tetraspanin family AA_permease PF00324.16 KKK19447.1 - 6.4e-80 268.7 42.8 9.5e-56 189.0 15.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KKK19447.1 - 7.1e-20 70.9 47.1 1e-16 60.5 18.1 2.1 1 1 1 2 2 2 2 Amino acid permease VWA_2 PF13519.1 KKK19448.1 - 0.0069 16.5 0.3 0.017 15.2 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Met_asp_mut_E PF06368.6 KKK19448.1 - 0.094 10.8 0.0 1.6 6.7 0.0 2.0 2 0 0 2 2 2 0 Methylaspartate mutase E chain (MutE) PmbA_TldD PF01523.11 KKK19448.1 - 5.3 6.2 5.7 1.2 8.3 0.2 2.4 1 1 2 3 3 3 0 Putative modulator of DNA gyrase PAN_4 PF14295.1 KKK19449.1 - 1.5e-07 30.9 36.8 0.0033 17.1 4.8 5.2 5 0 0 5 5 5 4 PAN domain PAN_3 PF08277.7 KKK19449.1 - 0.00014 21.4 33.8 0.0056 16.2 1.6 5.3 5 0 0 5 5 5 3 PAN-like domain PAPS_reduct PF01507.14 KKK19465.1 - 7.8e-44 149.5 0.1 1.8e-43 148.3 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.2 KKK19466.1 - 1.4e-14 54.6 0.0 2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK19466.1 - 7.3e-11 42.8 0.2 4.3e-09 37.0 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK19466.1 - 1e-08 35.0 0.0 1.1e-06 28.4 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KKK19466.1 - 6.8e-07 29.6 0.0 1.2e-05 25.6 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KKK19466.1 - 3.9e-05 22.9 0.0 0.00016 20.9 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.7 KKK19466.1 - 0.0022 17.0 0.2 0.0033 16.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) S6PP PF05116.8 KKK19466.1 - 0.033 13.5 0.1 0.43 9.8 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DUF2841 PF11001.3 KKK19467.1 - 5.2e-52 174.9 0.4 7.8e-52 174.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) BLYB PF05289.6 KKK19467.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein zf-C2H2 PF00096.21 KKK19477.1 - 5.3e-05 23.3 2.7 0.18 12.2 0.3 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK19477.1 - 8.9e-05 22.5 2.1 0.089 13.1 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK19477.1 - 0.019 15.2 0.0 0.053 13.8 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KKK19477.1 - 6 6.9 8.6 9 6.3 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger GTP_EFTU PF00009.22 KKK19478.1 - 2.5e-09 36.8 0.0 6.1e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KKK19478.1 - 0.00093 18.8 0.1 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 KKK19478.1 - 0.037 14.3 0.1 0.077 13.2 0.1 1.5 1 0 0 1 1 1 0 ABC transporter F-box-like PF12937.2 KKK19479.1 - 0.00087 18.9 0.1 0.003 17.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KKK19479.1 - 0.052 13.2 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain Fungal_trans PF04082.13 KKK19480.1 - 4.1e-21 75.0 0.0 7.5e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19480.1 - 2.3e-08 33.7 12.9 3.6e-08 33.1 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 KKK19481.1 - 8.1e-53 179.3 0.0 1.2e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 KKK19481.1 - 1.6e-20 72.9 0.0 3.2e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 KKK19481.1 - 2.4e-20 72.9 0.0 4.2e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 KKK19481.1 - 3.7e-11 43.2 0.0 9.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 KKK19481.1 - 0.00029 21.6 0.0 0.00061 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KKK19481.1 - 0.0019 18.0 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KKK19481.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 KKK19481.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase F420_oxidored PF03807.12 KKK19481.1 - 0.11 12.9 0.1 1.3 9.4 0.0 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.24 KKK19481.1 - 0.16 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 KKK19481.1 - 0.2 10.7 0.0 0.51 9.5 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Complex1_LYR PF05347.10 KKK19500.1 - 1.6e-14 53.4 0.4 2.4e-14 52.8 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK19500.1 - 2e-13 50.3 0.4 2.7e-13 49.9 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KKK19500.1 - 0.11 13.0 0.2 0.14 12.6 0.2 1.3 1 0 0 1 1 1 0 Complex1_LYR-like HIG_1_N PF04588.8 KKK19501.1 - 1.6e-26 91.7 0.1 2.2e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Nnf1 PF03980.9 KKK19501.1 - 0.039 13.9 0.7 0.062 13.3 0.5 1.3 1 0 0 1 1 1 0 Nnf1 Syja_N PF02383.13 KKK19502.1 - 1.5e-91 306.4 0.0 2.1e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Mur_ligase_M PF08245.7 KKK19502.1 - 3.3e-05 24.0 0.6 0.0024 17.9 0.4 3.1 1 1 0 1 1 1 1 Mur ligase middle domain Abhydrolase_6 PF12697.2 KKK19503.1 - 2.4e-13 50.4 1.8 5.2e-13 49.4 1.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK19503.1 - 5.7e-13 48.8 0.0 2.1e-12 47.0 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KKK19503.1 - 7.1e-06 25.7 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KKK19503.1 - 0.00082 18.9 0.0 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KKK19503.1 - 0.012 15.4 0.1 0.11 12.3 0.1 2.2 1 1 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 KKK19503.1 - 0.022 13.9 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cutinase PF01083.17 KKK19503.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Cutinase GTP_EFTU PF00009.22 KKK19504.1 - 2.9e-56 189.8 0.2 5.1e-56 189.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KKK19504.1 - 1.1e-32 111.6 0.0 2.5e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KKK19504.1 - 8.8e-31 105.9 0.0 2e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KKK19504.1 - 1.4e-22 79.3 0.0 3.1e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KKK19504.1 - 2.4e-11 43.5 0.1 6.9e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 NMT PF01233.14 KKK19505.1 - 1.3e-78 262.1 0.1 3.1e-78 261.0 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KKK19505.1 - 5.2e-73 244.4 0.3 1.6e-51 174.3 0.2 2.4 1 1 1 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KKK19505.1 - 7.3e-07 29.1 0.1 2.1e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK19505.1 - 0.0035 17.5 0.1 0.0098 16.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF427 PF04248.7 KKK19505.1 - 0.042 13.5 0.1 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Glycos_transf_1 PF00534.15 KKK19526.1 - 1.4e-12 47.3 0.0 3.6e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KKK19526.1 - 8.8e-05 22.6 0.0 0.00031 20.8 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 KKK19526.1 - 0.00011 21.8 0.0 0.0011 18.5 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) GPI-anchored PF10342.4 KKK19528.1 - 1.4e-17 63.9 3.5 1.7e-17 63.7 2.4 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family LT-IIB PF06453.6 KKK19528.1 - 0.042 13.5 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) adh_short_C2 PF13561.1 KKK19538.1 - 7.1e-25 88.1 0.0 9e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK19538.1 - 7.6e-20 71.4 0.2 1.6e-19 70.4 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK19538.1 - 3e-08 33.5 0.1 5.2e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KKK19538.1 - 0.0082 15.5 0.1 0.014 14.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KKK19538.1 - 0.0099 15.0 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK19538.1 - 0.05 14.0 0.3 0.096 13.1 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KKK19538.1 - 0.057 12.8 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.12 KKK19538.1 - 0.061 12.2 0.1 6.2 5.6 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 KKK19538.1 - 0.11 12.4 0.2 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Metallophos PF00149.23 KKK19540.1 - 2e-41 141.6 0.6 2.9e-41 141.0 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Voldacs PF03517.8 KKK19541.1 - 1.8e-28 99.0 0.3 6e-28 97.3 0.2 1.9 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF605 PF04652.11 KKK19541.1 - 1.3 8.3 10.2 1.7 7.9 7.0 1.2 1 0 0 1 1 1 0 Vta1 like Opi1 PF08618.5 KKK19543.1 - 6.2e-28 97.8 6.3 1.3e-24 86.9 0.0 3.1 1 1 2 3 3 3 2 Transcription factor Opi1 DUF3439 PF11921.3 KKK19543.1 - 0.4 10.4 8.6 0.77 9.5 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 KKK19543.1 - 1.2 6.7 2.7 1.4 6.5 1.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MFS_1 PF07690.11 KKK19544.1 - 2.1e-30 105.6 17.8 7e-30 103.9 12.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily RdRP PF05183.7 KKK19545.1 - 5.3e-126 421.6 0.0 7.4e-126 421.1 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.16 KKK19546.1 - 2.9e-74 250.1 30.8 3.2e-74 249.9 21.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK19546.1 - 2.4e-22 79.0 31.3 3e-22 78.7 21.7 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L19 PF01245.15 KKK19547.1 - 1.7e-19 69.6 0.3 3.1e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 DUF3850 PF12961.2 KKK19547.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) NmrA PF05368.8 KKK19548.1 - 1.1e-30 106.5 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK19548.1 - 1.8e-12 47.6 0.0 2.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KKK19548.1 - 3.1e-06 26.4 0.0 4.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KKK19548.1 - 3.1e-06 27.4 0.0 7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KKK19548.1 - 0.0036 17.3 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 KKK19548.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ion_trans_2 PF07885.11 KKK19549.1 - 1.6e-25 88.6 30.3 2.8e-15 55.7 5.5 3.6 3 1 1 4 4 4 2 Ion channel Ion_trans PF00520.26 KKK19549.1 - 0.0075 15.5 0.9 0.0075 15.5 0.7 4.2 3 3 1 4 4 4 2 Ion transport protein Claudin_2 PF13903.1 KKK19549.1 - 0.14 11.7 13.4 0.15 11.7 5.8 3.1 3 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF1345 PF07077.6 KKK19549.1 - 0.17 11.3 5.8 3.5 7.1 0.0 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1345) Opi1 PF08618.5 KKK19550.1 - 1.9e-63 214.9 2.0 6.8e-48 163.6 0.1 2.1 1 1 1 2 2 2 2 Transcription factor Opi1 Perilipin PF03036.11 KKK19550.1 - 0.0044 15.9 0.4 0.0054 15.6 0.3 1.2 1 1 0 1 1 1 1 Perilipin family DUF3631 PF12307.3 KKK19550.1 - 0.089 12.6 0.3 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) Globin PF00042.17 KKK19550.1 - 0.097 13.0 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Globin Bystin PF05291.6 KKK19550.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Bystin YadA_stalk PF05662.9 KKK19550.1 - 5.1 7.0 6.0 5.8 6.8 0.5 2.6 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin Ank_2 PF12796.2 KKK19551.1 - 7e-50 167.3 7.2 4e-14 52.7 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KKK19551.1 - 8.8e-45 148.3 24.4 5.1e-07 29.1 0.1 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KKK19551.1 - 4.3e-31 106.2 19.4 6.8e-08 32.5 0.1 7.8 2 2 7 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK19551.1 - 2.7e-30 101.3 14.8 9e-05 22.3 0.1 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 KKK19551.1 - 3.1e-29 100.7 12.3 6.4e-09 36.0 0.2 5.0 5 0 0 5 5 5 4 Ankyrin repeats (many copies) RVP PF00077.15 KKK19551.1 - 0.0073 16.1 0.0 10 6.0 0.0 3.8 4 0 0 4 4 4 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KKK19551.1 - 0.046 13.5 2.4 4.5 7.1 0.0 3.8 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease DUF4419 PF14388.1 KKK19552.1 - 3.2e-81 272.8 0.1 3.8e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) TFIIE_beta PF02186.10 KKK19553.1 - 1e-05 25.4 0.0 4.8e-05 23.2 0.0 2.2 2 1 0 2 2 2 1 TFIIE beta subunit core domain Mucin PF01456.12 KKK19553.1 - 0.1 12.4 7.0 0.2 11.4 4.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein TPR_MLP1_2 PF07926.7 KKK19554.1 - 2.8e-29 101.5 33.8 2.8e-29 101.5 23.4 15.3 6 4 7 15 15 15 4 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KKK19554.1 - 0.0013 18.6 3.8 0.0013 18.6 2.7 15.4 5 3 6 14 14 14 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uds1 PF15456.1 KKK19554.1 - 0.0063 16.5 11.3 0.0063 16.5 7.8 17.4 8 6 6 14 14 14 3 Up-regulated During Septation ASF1_hist_chap PF04729.8 KKK19555.1 - 1.3e-67 226.2 0.0 1.8e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 KKK19555.1 - 0.34 8.7 25.8 0.45 8.3 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.9 KKK19556.1 - 1.8e-92 310.0 0.1 1.8e-92 310.0 0.1 4.1 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KKK19556.1 - 7.9e-05 22.9 0.0 0.015 15.8 0.0 3.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK19556.1 - 0.00077 20.0 0.1 0.011 16.3 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 KKK19556.1 - 0.0052 16.5 0.1 0.0052 16.5 0.0 2.4 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat Lgl_C PF08596.5 KKK19557.1 - 7.9e-136 452.6 0.0 1.7e-135 451.4 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KKK19557.1 - 0.00033 20.4 1.1 2.6 8.0 0.1 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat KR PF08659.5 KKK19559.1 - 5.6e-51 172.7 4.3 9.3e-51 172.0 0.4 2.9 3 0 0 3 3 3 1 KR domain PS-DH PF14765.1 KKK19559.1 - 1e-49 169.3 1.5 1e-49 169.3 1.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 KKK19559.1 - 4.8e-45 153.4 4.5 8.3e-45 152.6 0.7 3.1 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 KKK19559.1 - 2e-05 24.7 0.1 6.3e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAP PF02037.22 KKK19560.1 - 4.3e-10 38.8 0.2 8.9e-10 37.8 0.2 1.6 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.1 KKK19560.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Solute_trans_a PF03619.11 KKK19562.1 - 2.4e-84 282.9 21.0 2.8e-84 282.6 14.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glyco_hydro_3 PF00933.16 KKK19564.1 - 4.2e-86 288.6 0.0 6e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK19564.1 - 2e-65 220.5 0.0 1.3e-64 217.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK19564.1 - 3.2e-22 78.2 0.2 1.8e-21 75.8 0.2 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KKK19564.1 - 8.3e-14 51.4 0.0 1.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DUF11 PF01345.13 KKK19564.1 - 0.0025 17.8 2.8 0.0041 17.1 1.1 2.0 1 1 1 2 2 2 1 Domain of unknown function DUF11 CARDB PF07705.6 KKK19564.1 - 0.013 15.5 0.1 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 CARDB DUF2808 PF10989.3 KKK19564.1 - 0.064 12.8 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) Abhydrolase_1 PF00561.15 KKK19565.1 - 7.2e-46 156.5 0.0 3.8e-45 154.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK19565.1 - 7e-14 52.2 0.1 4.2e-13 49.7 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK19565.1 - 0.0005 19.8 0.0 0.25 11.0 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KKK19565.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF2424 PF10340.4 KKK19565.1 - 0.1 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) NDUFA12 PF05071.11 KKK19567.1 - 3.3e-27 95.0 0.7 4.3e-27 94.6 0.5 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 KKK19568.1 - 6.3e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.17 KKK19568.1 - 0.0059 16.3 0.1 0.31 10.8 0.0 2.4 2 0 0 2 2 2 1 Phospholipase D Active site motif DnaG_DnaB_bind PF08278.6 KKK19568.1 - 0.08 13.1 0.0 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding CysG_dimeriser PF10414.4 KKK19568.1 - 0.099 12.1 0.1 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Ras PF00071.17 KKK19574.1 - 3.7e-38 130.4 0.0 6.9e-38 129.5 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK19574.1 - 2.8e-12 47.1 0.0 4.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK19574.1 - 1.6e-11 43.7 0.0 1.9e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK19574.1 - 0.00044 19.7 0.0 0.00092 18.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KKK19574.1 - 0.0011 18.1 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK19574.1 - 0.0089 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KKK19574.1 - 0.0093 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KKK19574.1 - 0.013 15.0 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KKK19574.1 - 0.018 15.2 0.0 0.068 13.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 KKK19574.1 - 0.029 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK19574.1 - 0.049 13.6 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 KKK19574.1 - 0.095 11.9 0.0 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KKK19574.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF1253 PF06862.7 KKK19575.1 - 4.9e-163 542.6 0.0 7e-163 542.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 KKK19575.1 - 0.044 13.2 0.9 3.5 7.0 0.5 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase JAB PF01398.16 KKK19576.1 - 1.4e-16 60.2 0.0 2.3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KKK19576.1 - 3.2e-16 59.4 0.1 5.8e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 KKK19576.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) CTP_transf_2 PF01467.21 KKK19577.1 - 6.3e-22 78.3 0.0 9.8e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase PP2C PF00481.16 KKK19578.1 - 6.7e-81 271.4 0.0 1.1e-80 270.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KKK19578.1 - 0.0013 18.1 0.0 0.0028 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C Phage_prot_Gp6 PF05133.9 KKK19578.1 - 0.067 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like EamA PF00892.15 KKK19579.1 - 3.5e-16 59.3 21.2 1.2e-09 38.2 0.8 3.3 3 0 0 3 3 3 3 EamA-like transporter family EmrE PF13536.1 KKK19579.1 - 0.00037 20.6 3.3 0.00037 20.6 2.3 4.1 3 1 0 3 3 3 2 Multidrug resistance efflux transporter SR-25 PF10500.4 KKK19579.1 - 3.2 7.1 18.3 5.9 6.2 12.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1769 PF08588.5 KKK19586.1 - 1.5e-27 95.2 0.1 3e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) AAA_13 PF13166.1 KKK19587.1 - 0.00025 19.6 0.0 0.00025 19.6 0.0 3.0 2 1 1 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 KKK19587.1 - 0.0028 16.8 11.1 0.028 13.6 1.1 3.8 2 1 2 4 4 4 3 Reovirus sigma C capsid protein Sec3_C_2 PF15278.1 KKK19587.1 - 0.0075 16.3 0.3 0.038 14.1 0.0 2.3 2 0 0 2 2 2 1 Sec3 exocyst complex subunit ADIP PF11559.3 KKK19587.1 - 6.7 6.5 38.7 0.68 9.8 0.2 4.8 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding Ribosomal_S8 PF00410.14 KKK19588.1 - 6.9e-25 87.3 0.0 1.1e-24 86.6 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 FAD_binding_3 PF01494.14 KKK19589.1 - 9.8e-16 57.7 0.0 3e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KKK19589.1 - 5.4e-05 23.5 0.0 0.00017 21.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK19589.1 - 0.0003 20.7 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK19589.1 - 0.00034 19.6 0.1 0.00076 18.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KKK19589.1 - 0.0031 16.0 0.1 0.0048 15.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KKK19589.1 - 0.0051 16.7 0.0 0.017 15.0 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK19589.1 - 0.031 13.3 3.5 0.04 12.9 0.4 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.5 KKK19589.1 - 0.033 13.0 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.17 KKK19589.1 - 0.056 12.2 0.1 0.098 11.5 0.1 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KKK19589.1 - 0.059 12.2 0.3 0.16 10.7 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Fungal_trans PF04082.13 KKK19590.1 - 5.2e-08 32.0 0.0 1.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19590.1 - 0.00027 20.7 10.3 0.00055 19.7 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DsbC_N PF10411.4 KKK19590.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Glyco_hydro_25 PF01183.15 KKK19591.1 - 1.7e-33 115.9 0.0 2.2e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Thioredoxin_7 PF13899.1 KKK19591.1 - 0.052 13.5 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Peptidase_M24 PF00557.19 KKK19592.1 - 4.9e-44 150.4 0.0 6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KKK19592.1 - 0.0002 21.1 4.9 0.0002 21.1 3.4 2.2 2 0 0 2 2 2 1 MYND finger MFS_1 PF07690.11 KKK19593.1 - 6.7e-43 146.7 45.0 1e-42 146.1 31.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK19593.1 - 2.6e-14 52.6 9.4 2.6e-14 52.6 6.5 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter EF-hand_1 PF00036.27 KKK19593.1 - 1.1e-13 49.3 1.3 1.3e-06 27.2 0.2 2.6 2 0 0 2 2 2 2 EF hand ZZ PF00569.12 KKK19593.1 - 1.8e-11 43.3 4.8 3.3e-11 42.5 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.1 KKK19593.1 - 1.4e-10 41.1 2.0 3.5e-10 39.8 1.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KKK19593.1 - 2.5e-10 39.3 2.5 0.00019 21.0 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KKK19593.1 - 1.5e-08 34.0 1.5 0.0024 17.4 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KKK19593.1 - 1.5e-05 24.1 2.5 0.014 14.7 0.1 2.6 2 0 0 2 2 2 2 EF hand DUF3506 PF12014.3 KKK19594.1 - 3e-51 172.7 0.0 5.4e-51 171.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KKK19594.1 - 1.8e-11 43.5 0.7 4.3e-11 42.3 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK19594.1 - 1e-07 31.3 0.1 1.1e-06 28.0 0.1 2.3 2 0 0 2 2 2 1 F-box domain DUF1748 PF08520.5 KKK19595.1 - 5.4e-37 125.2 0.1 6.1e-37 125.1 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Iso_dh PF00180.15 KKK19598.1 - 3.7e-96 322.1 0.0 1.2e-95 320.4 0.0 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase 3Beta_HSD PF01073.14 KKK19600.1 - 5.2e-58 195.9 0.0 6.4e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK19600.1 - 4.1e-37 127.8 0.0 5.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KKK19600.1 - 7.5e-19 67.6 0.0 1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KKK19600.1 - 5.7e-15 54.9 0.0 1.3e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KKK19600.1 - 3.3e-11 43.4 0.1 7.2e-11 42.2 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KKK19600.1 - 7.1e-10 39.1 0.0 9.6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KKK19600.1 - 2.6e-09 36.4 0.0 5e-08 32.1 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 KKK19600.1 - 1.5e-05 24.7 0.1 5.7e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KKK19600.1 - 0.00076 18.5 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 KKK19600.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family PK PF00224.16 KKK19602.1 - 4e-174 578.1 2.2 5e-174 577.8 1.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KKK19602.1 - 1.7e-31 108.2 0.0 4.4e-31 106.8 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KKK19602.1 - 4e-05 22.6 0.8 9.5e-05 21.3 0.6 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KKK19602.1 - 0.006 15.5 0.1 0.12 11.1 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF2036 PF09724.4 KKK19603.1 - 8e-15 54.7 0.0 3.1e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Nucleoplasmin PF03066.10 KKK19603.1 - 0.0012 18.3 1.7 0.0019 17.7 1.2 1.3 1 0 0 1 1 1 1 Nucleoplasmin DUF4611 PF15387.1 KKK19603.1 - 0.0016 18.4 2.8 0.0041 17.2 1.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) FAM176 PF14851.1 KKK19603.1 - 0.008 15.8 0.6 0.017 14.7 0.4 1.5 1 0 0 1 1 1 1 FAM176 family RXT2_N PF08595.6 KKK19603.1 - 0.093 12.5 1.8 0.18 11.6 1.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 KKK19603.1 - 0.21 11.8 9.6 0.45 10.7 6.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Bd3614_N PF14442.1 KKK19603.1 - 0.45 10.4 4.6 1 9.3 3.2 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Sigma70_ner PF04546.8 KKK19603.1 - 0.91 9.0 5.4 1.8 8.1 3.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KKK19603.1 - 0.94 8.6 7.4 1.6 7.9 5.1 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 KKK19603.1 - 1.1 9.5 7.6 3 8.2 5.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Acetyltransf_7 PF13508.1 KKK19604.1 - 1.7e-06 28.1 0.0 3.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK19604.1 - 0.00012 21.8 0.0 0.00045 20.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK19604.1 - 0.00027 20.8 0.2 0.00094 19.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK19604.1 - 0.0027 17.4 0.1 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.1 KKK19604.1 - 0.0033 17.5 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KKK19604.1 - 0.0045 17.0 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Anp1 PF03452.9 KKK19605.1 - 4.6e-122 406.3 0.0 7e-122 405.7 0.0 1.3 1 0 0 1 1 1 1 Anp1 adh_short PF00106.20 KKK19605.1 - 1.5e-11 44.5 0.0 2.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK19605.1 - 2.4e-06 27.3 0.0 4.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK19605.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK19605.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein IBR PF01485.16 KKK19606.1 - 1.2e-06 28.2 7.4 1.2e-06 28.2 5.1 3.6 3 1 0 3 3 3 2 IBR domain DnaJ-X PF14308.1 KKK19625.1 - 1.2e-70 237.0 4.3 3.7e-70 235.3 3.3 1.7 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KKK19625.1 - 3e-26 90.9 0.2 8.1e-26 89.5 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain SQS_PSY PF00494.14 KKK19626.1 - 1.4e-41 142.5 0.0 3.9e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase Peroxin-22 PF12827.2 KKK19626.1 - 0.11 12.2 0.1 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Hemerythrin PF01814.18 KKK19627.1 - 3.6e-07 30.3 0.1 1.2e-06 28.6 0.1 1.8 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Peptidase_A4 PF01828.12 KKK19628.1 - 6.7e-86 286.6 9.2 8.1e-86 286.3 6.4 1.1 1 0 0 1 1 1 1 Peptidase A4 family S-methyl_trans PF02574.11 KKK19629.1 - 5.9e-26 91.4 0.0 1.3e-24 87.0 0.0 2.5 1 1 0 1 1 1 1 Homocysteine S-methyltransferase Tail_tube PF10618.4 KKK19629.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Phage tail tube protein SRR1 PF07985.7 KKK19630.1 - 0.0076 16.1 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 SRR1 ketoacyl-synt PF00109.21 KKK19631.1 - 3.2e-18 66.1 0.0 7.4e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KKK19631.1 - 2.8e-16 60.0 0.0 5.1e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 KKK19631.1 - 4.6e-16 58.7 0.0 1e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 KKK19631.1 - 8.6e-14 51.3 0.0 1.8e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.20 KKK19631.1 - 3.7e-06 26.9 0.0 6.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.18 KKK19631.1 - 0.11 11.4 1.8 0.75 8.7 0.0 2.3 2 0 0 2 2 2 0 Thiolase, N-terminal domain DUF3881 PF12997.2 KKK19631.1 - 0.39 9.6 0.0 0.72 8.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) Acyl_transf_1 PF00698.16 KKK19632.1 - 3.8e-50 171.0 0.0 1.9e-48 165.4 0.0 2.8 2 1 0 2 2 2 1 Acyl transferase domain DUF1729 PF08354.5 KKK19632.1 - 1.3e-28 98.5 0.1 3.3e-28 97.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 KKK19632.1 - 3.9e-24 84.3 0.0 8.7e-24 83.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KKK19632.1 - 6.5e-07 29.2 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KKK19632.1 - 0.011 14.9 0.3 0.043 12.9 0.2 1.9 1 1 0 1 1 1 0 Nitronate monooxygenase FAD_binding_3 PF01494.14 KKK19633.1 - 1.3e-13 50.7 5.0 8.1e-10 38.2 2.0 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK19633.1 - 0.00091 18.2 2.4 0.0012 17.7 1.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK19633.1 - 0.0019 18.1 0.4 0.0051 16.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KKK19633.1 - 0.017 14.7 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KKK19633.1 - 0.023 15.0 1.4 0.084 13.2 0.2 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK19633.1 - 0.044 13.5 0.1 0.18 11.5 0.1 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KKK19633.1 - 0.082 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 KKK19633.1 - 0.099 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KKK19633.1 - 0.12 12.7 0.5 0.33 11.4 0.3 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2OG-FeII_Oxy_2 PF13532.1 KKK19634.1 - 4.4e-15 56.0 0.0 5.7e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KKK19634.1 - 4.4e-10 39.7 0.0 7.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KKK19634.1 - 0.042 14.3 0.1 0.18 12.3 0.1 2.2 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RrnaAD PF00398.15 KKK19635.1 - 1.8e-62 210.7 0.0 2.3e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KKK19635.1 - 5.7e-10 39.2 0.0 4.8e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK19635.1 - 3.6e-05 24.3 0.0 6.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK19635.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KKK19635.1 - 0.0032 16.6 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KKK19635.1 - 0.0036 16.8 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KKK19635.1 - 0.0046 16.3 0.0 0.031 13.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KKK19635.1 - 0.05 13.9 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KKK19635.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lipase_3 PF01764.20 KKK19637.1 - 1.2e-36 125.3 0.0 1.8e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KKK19637.1 - 4.2e-08 32.9 0.3 9.8e-08 31.7 0.2 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.3 KKK19637.1 - 0.02 14.2 0.8 0.36 10.1 0.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Transferase PF02458.10 KKK19638.1 - 2.2e-07 29.7 0.0 4.4e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 Transferase family AraC_binding PF02311.14 KKK19638.1 - 0.0085 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain MFS_1 PF07690.11 KKK19639.1 - 5.4e-34 117.4 28.5 1.4e-33 116.0 19.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK19639.1 - 2.4e-18 65.9 8.8 3e-18 65.6 6.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KKK19639.1 - 1e-15 56.9 9.9 1.3e-15 56.6 6.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 KKK19639.1 - 0.015 13.8 13.8 0.061 11.7 8.7 2.1 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like DUF1726 PF08351.6 KKK19639.1 - 0.21 11.3 0.6 0.49 10.1 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) MFS_1 PF07690.11 KKK19640.1 - 1.3e-05 24.0 28.6 7.6e-05 21.5 13.3 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK19640.1 - 0.0042 15.3 3.0 0.0043 15.2 2.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.21 KKK19641.1 - 6.4e-69 232.2 0.0 1.2e-68 231.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KKK19641.1 - 2e-29 101.8 0.0 9e-29 99.7 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KKK19641.1 - 1.6e-27 96.0 0.0 2.6e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 KKK19641.1 - 9.6e-27 94.1 0.0 5e-26 91.7 0.0 2.1 1 1 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 KKK19641.1 - 1.7e-15 57.0 0.3 4.5e-15 55.6 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KKK19641.1 - 2.1e-13 50.5 0.0 7.1e-13 48.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KKK19641.1 - 1.3e-07 31.2 0.0 3e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 KKK19641.1 - 3.3e-07 30.0 0.0 7.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK19641.1 - 1.5e-05 25.3 0.0 0.00012 22.4 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK19641.1 - 6.9e-05 22.6 0.0 0.00028 20.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK19641.1 - 7.5e-05 23.0 0.0 0.00028 21.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 KKK19641.1 - 0.00018 21.4 0.3 0.00078 19.3 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Methyltransf_18 PF12847.2 KKK19641.1 - 0.00082 19.9 0.0 0.0046 17.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 KKK19641.1 - 0.011 14.7 0.1 0.029 13.3 0.1 1.7 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KKK19641.1 - 0.013 14.6 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 KKK19641.1 - 0.063 11.9 0.2 4.9 5.7 0.0 2.5 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family ACP_syn_III PF08545.5 KKK19641.1 - 0.071 12.7 0.7 0.19 11.3 0.5 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_10 PF13460.1 KKK19641.1 - 0.11 12.5 0.2 4 7.4 0.2 3.1 2 1 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 KKK19641.1 - 0.34 9.7 0.0 0.59 8.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RrnaAD PF00398.15 KKK19641.1 - 0.56 9.1 0.0 1 8.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fungal_trans PF04082.13 KKK19643.1 - 3.4e-17 62.1 0.6 5.1e-17 61.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cellulase PF00150.13 KKK19644.1 - 2.1e-19 69.8 0.4 2.7e-19 69.4 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KKK19644.1 - 0.0019 17.3 0.1 0.012 14.7 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.12 KKK19644.1 - 0.0062 15.4 0.0 0.018 13.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Sugar_tr PF00083.19 KKK19645.1 - 7e-138 459.9 24.6 8e-138 459.7 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK19645.1 - 1.2e-20 73.5 46.9 2.6e-18 65.8 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_C PF00043.20 KKK19646.1 - 3.8e-09 36.4 0.0 8.1e-09 35.3 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK19646.1 - 3.4e-08 33.8 0.0 5.7e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK19646.1 - 3.4e-08 33.2 0.1 5.5e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_tranf_2_3 PF13641.1 KKK19647.1 - 5.7e-12 45.9 0.0 9.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KKK19647.1 - 0.00018 20.8 0.0 0.00043 19.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KKK19647.1 - 0.00037 20.2 0.0 0.00061 19.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Response_reg PF00072.19 KKK19673.1 - 3.7e-21 75.2 0.1 4.6e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain CENP-B_dimeris PF09026.5 KKK19674.1 - 0.042 14.0 1.6 0.48 10.6 0.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sugar_tr PF00083.19 KKK19675.1 - 6.8e-87 291.9 24.7 8.2e-87 291.6 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK19675.1 - 2.6e-27 95.4 20.6 5.9e-27 94.3 12.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK19675.1 - 0.00011 20.7 29.4 0.0013 17.2 4.6 2.9 2 2 0 2 2 2 2 MFS/sugar transport protein PARG_cat PF05028.9 KKK19676.1 - 5e-28 98.3 0.0 1.4e-27 96.8 0.0 1.6 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) YndJ PF14158.1 KKK19677.1 - 0.1 11.6 1.0 0.14 11.1 0.7 1.1 1 0 0 1 1 1 0 YndJ-like protein NmrA PF05368.8 KKK19679.1 - 9.7e-37 126.4 0.0 1.2e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK19679.1 - 3e-19 69.7 0.0 4.5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK19679.1 - 0.0017 17.1 0.1 0.0049 15.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK19679.1 - 0.0018 17.7 0.0 0.0078 15.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KKK19679.1 - 0.034 14.1 0.0 0.066 13.2 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.7 KKK19679.1 - 0.16 10.8 0.0 2.6 6.9 0.0 2.3 1 1 0 2 2 2 0 Male sterility protein SHR3_chaperone PF08229.6 KKK19680.1 - 1.8e-76 255.4 0.0 2.2e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Tad PF13400.1 KKK19680.1 - 0.25 11.4 0.3 0.25 11.4 0.2 3.5 4 0 0 4 4 4 0 Putative Flp pilus-assembly TadE/G-like Ribosomal_60s PF00428.14 KKK19680.1 - 0.35 11.3 8.3 0.52 10.7 5.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Zip PF02535.17 KKK19681.1 - 1.2e-35 123.0 10.1 1.2e-35 123.0 7.0 1.8 2 0 0 2 2 2 1 ZIP Zinc transporter Acetyltransf_7 PF13508.1 KKK19682.1 - 5.3e-08 32.9 0.0 5.9e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK19682.1 - 6.6e-07 29.2 0.0 9.5e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KKK19682.1 - 1.3e-06 28.4 0.0 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK19682.1 - 0.00011 22.0 0.0 0.0095 15.7 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK19682.1 - 0.00026 20.6 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KKK19682.1 - 0.0011 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 KKK19682.1 - 0.0017 17.9 0.0 0.0057 16.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Hydrophobin PF01185.13 KKK19683.1 - 1.8e-13 50.7 7.8 2.4e-13 50.3 5.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin bZIP_1 PF00170.16 KKK19684.1 - 5.1e-08 32.7 9.3 7.8e-08 32.1 6.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK19684.1 - 9.6e-05 22.1 13.1 0.00016 21.4 8.8 1.5 1 1 1 2 2 2 2 Basic region leucine zipper Macoilin PF09726.4 KKK19684.1 - 0.0013 17.0 0.1 0.0013 17.0 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein bZIP_Maf PF03131.12 KKK19684.1 - 0.0018 18.5 6.5 0.0028 17.9 4.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor CASP_C PF08172.7 KKK19684.1 - 0.0048 15.9 3.3 0.0074 15.3 2.3 1.2 1 0 0 1 1 1 1 CASP C terminal FTA4 PF13093.1 KKK19684.1 - 0.0085 15.5 0.3 0.011 15.1 0.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2353 PF09789.4 KKK19684.1 - 0.022 14.0 3.0 0.027 13.7 2.1 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DivIC PF04977.10 KKK19684.1 - 0.038 13.4 2.0 0.059 12.8 1.4 1.2 1 0 0 1 1 1 0 Septum formation initiator TEX13 PF15186.1 KKK19684.1 - 0.038 13.5 2.5 0.06 12.9 1.7 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family GAS PF13851.1 KKK19684.1 - 0.04 13.1 2.5 0.057 12.6 1.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 KKK19684.1 - 0.15 11.8 1.6 0.29 10.8 1.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2730 PF10805.3 KKK19684.1 - 0.15 11.8 2.3 0.22 11.2 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Striatin PF08232.7 KKK19684.1 - 0.39 11.0 5.9 0.073 13.3 1.1 1.9 1 1 1 2 2 2 0 Striatin family DDE_Tnp_IS1595 PF12762.2 KKK19685.1 - 0.042 13.6 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 ISXO2-like transposase domain His_Phos_2 PF00328.17 KKK19686.1 - 1.3e-36 126.6 0.0 1.5e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AA_permease_2 PF13520.1 KKK19687.1 - 4.7e-52 176.9 42.2 6e-52 176.6 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK19687.1 - 3.4e-20 71.8 36.2 4.5e-20 71.4 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 KKK19690.1 - 8.2e-59 199.3 0.0 1.2e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_10 PF00331.15 KKK19691.1 - 1.7e-98 329.5 1.4 4e-77 259.3 0.3 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 DUF4339 PF14237.1 KKK19691.1 - 0.01 15.4 0.1 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Arrestin_N PF00339.24 KKK19692.1 - 1.4e-13 50.8 0.0 9e-12 45.0 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KKK19692.1 - 1.2e-08 35.1 0.0 6.9e-05 22.9 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain PWI PF01480.12 KKK19697.1 - 8.7e-12 44.9 0.6 2e-11 43.8 0.4 1.6 1 0 0 1 1 1 1 PWI domain SUKH_6 PF14568.1 KKK19697.1 - 0.066 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Rif1_N PF12231.3 KKK19697.1 - 0.28 10.1 0.1 0.4 9.5 0.0 1.1 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal MR_MLE_C PF13378.1 KKK19698.1 - 9.2e-18 64.2 0.1 2.5e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KKK19698.1 - 2.6e-13 50.2 0.0 1.8e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KKK19698.1 - 3.3e-07 30.2 0.0 6.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PGI PF00342.14 KKK19700.1 - 2e-219 729.0 0.4 2.3e-219 728.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Rhodanese PF00581.15 KKK19701.1 - 1.9e-13 50.7 0.0 2.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S21 PF01165.15 KKK19702.1 - 1.6e-10 40.2 1.6 2.4e-10 39.6 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 ArfGap PF01412.13 KKK19703.1 - 4.5e-34 116.7 0.7 7.5e-34 116.0 0.5 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 KKK19703.1 - 6 6.4 7.9 0.17 11.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) TIM21 PF08294.6 KKK19704.1 - 3.9e-42 143.3 0.0 4.8e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KKK19704.1 - 1.5e-05 24.4 0.0 3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 SAP30_Sin3_bdg PF13867.1 KKK19705.1 - 1e-13 50.8 0.2 5.5e-13 48.5 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 LTV PF04180.9 KKK19708.1 - 6.2e-74 250.0 6.9 1.8e-73 248.4 4.8 1.7 1 1 0 1 1 1 1 Low temperature viability protein DGF-1_C PF11040.3 KKK19708.1 - 0.81 9.6 6.6 0.39 10.6 0.7 3.2 3 1 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus YL1 PF05764.8 KKK19708.1 - 2.3 7.7 8.0 0.31 10.6 2.1 2.0 2 1 0 2 2 2 0 YL1 nuclear protein Acyl-CoA_dh_1 PF00441.19 KKK19709.1 - 1.9e-27 96.1 1.3 3.2e-27 95.4 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KKK19709.1 - 3.6e-16 58.3 0.0 8.1e-16 57.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Spo12 PF05032.7 KKK19709.1 - 5.7e-16 57.8 2.8 1.2e-15 56.7 1.9 1.6 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_2 PF08028.6 KKK19709.1 - 2.8e-13 50.2 2.7 4.7e-13 49.5 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KKK19709.1 - 5.5e-12 46.2 0.0 1.2e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Pol_alpha_B_N PF08418.5 KKK19709.1 - 0.04 13.4 3.2 0.067 12.7 2.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal FAM110_C PF14160.1 KKK19709.1 - 0.06 14.2 1.3 0.11 13.4 0.9 1.4 1 0 0 1 1 1 0 Centrosome-associated C terminus MMR_HSR1 PF01926.18 KKK19710.1 - 7e-17 61.4 0.1 2.6e-14 53.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK19710.1 - 1.6e-07 30.7 0.1 4.8e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 KKK19710.1 - 0.0004 19.6 0.0 0.00077 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KKK19710.1 - 0.00051 19.9 4.7 0.099 12.4 0.2 3.5 3 1 0 3 3 3 2 Dynamin family AIG1 PF04548.11 KKK19710.1 - 0.0074 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KKK19710.1 - 0.034 14.6 0.3 0.19 12.2 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Pkinase PF00069.20 KKK19711.1 - 4.3e-58 196.5 0.0 6.9e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19711.1 - 2.4e-31 108.7 0.0 3.3e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK19711.1 - 4.8e-10 38.8 0.0 2e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KKK19711.1 - 0.099 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.8 KKK19712.1 - 2.4e-33 114.7 0.0 4.6e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF2808 PF10989.3 KKK19712.1 - 0.031 13.8 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DUF1451 PF07295.6 KKK19712.1 - 0.047 13.4 2.6 0.096 12.4 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Zn_clus PF00172.13 KKK19723.1 - 9.1e-11 41.4 8.5 1.9e-10 40.4 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK19723.1 - 6.8e-09 34.9 0.0 1.4e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KKK19723.1 - 0.022 13.3 0.0 1.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain Glyco_hydro_98C PF08307.6 KKK19723.1 - 0.33 10.1 0.0 0.51 9.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain DUF3455 PF11937.3 KKK19724.1 - 4.9e-18 65.6 0.0 6.3e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) MitoNEET_N PF10660.4 KKK19724.1 - 0.25 11.2 1.1 14 5.6 0.0 2.9 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus Cation_efflux PF01545.16 KKK19725.1 - 5.7e-37 127.3 10.9 7.5e-37 126.9 7.5 1.1 1 0 0 1 1 1 1 Cation efflux family Homeobox PF00046.24 KKK19726.1 - 7.4e-15 54.3 3.2 1.6e-14 53.2 2.2 1.6 1 0 0 1 1 1 1 Homeobox domain PhyH PF05721.8 KKK19727.1 - 1.3e-18 67.8 0.0 2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.19 KKK19728.1 - 1.9e-97 326.6 26.8 2.2e-97 326.4 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK19728.1 - 4.1e-32 111.2 48.1 1.3e-27 96.4 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK19728.1 - 0.00046 18.5 1.0 0.0008 17.7 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3180 PF11377.3 KKK19728.1 - 0.035 13.9 4.0 0.29 10.9 0.7 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3180) DUF1776 PF08643.5 KKK19735.1 - 2e-105 352.2 0.0 2.4e-105 351.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.20 KKK19735.1 - 0.025 14.4 0.0 0.056 13.3 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase WLM PF08325.5 KKK19736.1 - 5.8e-61 205.6 0.0 8.3e-61 205.1 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KKK19736.1 - 7.3e-05 21.7 21.3 0.00038 19.4 3.5 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DUF45 PF01863.12 KKK19736.1 - 0.00078 19.2 2.2 0.0016 18.2 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 KKK19736.1 - 0.00093 18.8 0.3 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 SprT-like family DZR PF12773.2 KKK19736.1 - 0.035 13.9 12.2 0.76 9.6 8.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon Mito_carr PF00153.22 KKK19738.1 - 2.4e-47 158.5 3.8 6.5e-17 61.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 KKK19739.1 - 1.6e-50 167.2 17.2 3.7e-09 36.1 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KKK19739.1 - 1.3e-10 40.0 5.6 9.7e-05 20.6 0.1 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box-like PF12937.2 KKK19739.1 - 1.5e-10 40.6 0.4 3.1e-10 39.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK19739.1 - 0.00054 19.5 0.3 0.0013 18.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain Lipase_GDSL PF00657.17 KKK19740.1 - 4.5e-14 52.8 0.0 6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KKK19740.1 - 4.2e-13 49.8 0.1 6.4e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KKK19740.1 - 0.03 14.0 0.1 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family MAT1 PF06391.8 KKK19740.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Histone PF00125.19 KKK19741.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KKK19741.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KKK19741.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KKK19741.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KKK19741.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KKK19741.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 KKK19741.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Mito_carr PF00153.22 KKK19742.1 - 4.5e-35 119.2 8.9 1.1e-13 50.6 0.0 4.2 4 0 0 4 4 4 3 Mitochondrial carrier protein SH3_9 PF14604.1 KKK19742.1 - 8.7e-07 28.4 0.1 2.9e-06 26.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KKK19742.1 - 0.0017 17.7 0.2 0.0034 16.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK19742.1 - 0.01 15.3 0.3 0.032 13.7 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain DUF883 PF05957.8 KKK19742.1 - 0.073 13.4 0.3 0.073 13.4 0.2 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Annexin PF00191.15 KKK19743.1 - 2.6e-59 196.9 3.2 4.7e-17 61.6 0.0 4.1 4 0 0 4 4 4 4 Annexin DUF1645 PF07816.6 KKK19743.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) SapB_1 PF05184.10 KKK19743.1 - 0.17 11.7 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Saposin-like type B, region 1 CBM_21 PF03370.8 KKK19744.1 - 1.2e-35 121.9 3.2 2e-35 121.1 2.2 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KKK19744.1 - 0.55 10.3 4.6 2.3 8.3 3.2 1.9 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) Zn_clus PF00172.13 KKK19745.1 - 8.9e-11 41.5 11.8 2.1e-10 40.3 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 KKK19745.1 - 0.091 12.2 3.9 0.22 11.0 2.7 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 adh_short PF00106.20 KKK19746.1 - 3.2e-25 88.9 2.8 1.8e-24 86.5 1.3 2.2 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK19746.1 - 2.4e-09 37.1 3.4 3.5e-07 30.0 2.2 2.9 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 KKK19746.1 - 2.8e-08 33.8 0.0 4.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KKK19746.1 - 8.9e-05 22.5 0.3 0.00063 19.8 0.1 2.3 1 1 0 2 2 2 1 NADH(P)-binding B12-binding PF02310.14 KKK19746.1 - 0.037 13.9 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain UPF0146 PF03686.8 KKK19746.1 - 0.037 13.8 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) PhnI PF05861.7 KKK19746.1 - 0.085 11.3 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Zn_clus PF00172.13 KKK19747.1 - 3.5e-10 39.6 9.7 3.5e-10 39.6 6.7 1.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.3 KKK19747.1 - 0.084 12.6 11.1 0.18 11.5 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Opy2 PF09463.5 KKK19747.1 - 6.3 6.9 11.8 0.57 10.3 2.0 2.9 3 0 0 3 3 3 0 Opy2 protein Pyr_redox_3 PF13738.1 KKK19748.1 - 1.3e-27 97.1 0.0 5e-27 95.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK19748.1 - 7.4e-13 47.5 0.0 1.3e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK19748.1 - 1.5e-10 40.4 0.0 2.2e-09 36.7 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KKK19748.1 - 1.6e-07 31.3 0.0 1.6e-06 28.1 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK19748.1 - 6.2e-06 26.0 0.7 0.0047 16.7 0.2 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KKK19748.1 - 0.00028 20.8 0.1 0.00079 19.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK19748.1 - 0.00057 19.0 0.2 0.0037 16.3 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KKK19748.1 - 0.00074 19.8 0.3 0.61 10.5 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK19748.1 - 0.055 11.9 0.0 7.3 4.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 KKK19748.1 - 0.07 12.0 0.5 3.9 6.2 0.1 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase STE PF02200.11 KKK19749.1 - 5.4e-62 206.7 0.1 1e-61 205.8 0.1 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 KKK19749.1 - 4.9e-12 45.4 9.4 1.1e-06 28.6 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK19749.1 - 1e-09 37.9 10.2 8.8e-05 22.5 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK19749.1 - 1e-09 38.1 4.3 1e-09 38.1 3.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KKK19749.1 - 0.0057 16.5 0.2 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK19749.1 - 0.016 15.3 0.3 0.45 10.7 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KKK19749.1 - 0.034 14.5 2.3 0.057 13.7 1.6 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-RING_3 PF14369.1 KKK19749.1 - 0.051 13.5 0.2 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 zinc-finger zf-Di19 PF05605.7 KKK19749.1 - 0.78 9.9 3.4 2 8.5 2.3 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KKK19749.1 - 1.1 9.0 4.9 1.8 8.2 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MFS_2 PF13347.1 KKK19750.1 - 2.1e-07 29.7 12.5 7.1e-07 27.9 4.2 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Na_H_Exchanger PF00999.16 KKK19751.1 - 1e-65 221.7 40.2 1.3e-65 221.4 27.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEP PF10167.4 KKK19752.1 - 0.042 13.5 0.1 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein YolD PF08863.5 KKK19752.1 - 0.066 13.0 0.4 0.18 11.6 0.3 1.8 1 0 0 1 1 1 0 YolD-like protein APH PF01636.18 KKK19753.1 - 9.9e-14 51.6 0.0 1.5e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK19753.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KKK19753.1 - 0.0012 18.2 0.0 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 RIO1 family ADH_N PF08240.7 KKK19754.1 - 2.4e-28 98.0 0.1 5.5e-28 96.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK19754.1 - 3e-18 65.6 0.5 1.3e-17 63.5 0.4 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK19754.1 - 0.0025 18.7 0.0 0.0043 17.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KKK19754.1 - 0.0048 16.4 0.2 0.0079 15.7 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KKK19754.1 - 0.016 14.3 0.2 0.03 13.4 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SNF2_N PF00176.18 KKK19755.1 - 3.1e-70 236.3 4.1 3.1e-70 236.3 2.9 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 KKK19755.1 - 4.3e-52 175.8 20.2 4.3e-52 175.8 14.0 4.5 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 KKK19755.1 - 1.2e-16 60.3 0.0 3.5e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain His_biosynth PF00977.16 KKK19756.1 - 8.3e-32 110.2 0.0 1e-31 110.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Acetone_carb_G PF08882.6 KKK19756.1 - 0.096 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit DUF4602 PF15375.1 KKK19757.1 - 1.4e-06 28.4 17.9 1.4e-06 28.4 12.4 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4602) Daxx PF03344.10 KKK19757.1 - 0.17 10.3 25.9 0.21 10.0 18.0 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 KKK19757.1 - 0.25 10.5 26.2 0.44 9.7 18.1 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KKK19757.1 - 0.31 8.9 23.6 0.38 8.6 16.3 1.3 1 0 0 1 1 1 0 Nop14-like family Aminotran_1_2 PF00155.16 KKK19758.1 - 9.8e-74 248.4 0.1 8.5e-55 186.1 0.1 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KKK19758.1 - 1.5e-05 23.5 0.0 2.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KKK19758.1 - 1.9e-05 23.6 0.0 3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KKK19758.1 - 0.00031 19.8 0.2 0.00067 18.7 0.2 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KKK19758.1 - 0.016 14.3 0.3 0.035 13.2 0.2 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase AA_permease_2 PF13520.1 KKK19759.1 - 1.5e-61 208.2 48.6 1.8e-61 207.9 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK19759.1 - 3.4e-12 45.4 40.2 4.7e-12 45.0 27.9 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_13 PF13880.1 KKK19759.1 - 0.015 15.0 0.0 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase zf-C2H2_jaz PF12171.3 KKK19763.1 - 0.001 19.1 3.1 0.19 11.8 0.3 3.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KKK19763.1 - 0.0017 18.5 39.9 0.08 13.3 1.0 7.0 6 0 0 6 6 6 4 C2H2-type zinc finger DAO PF01266.19 KKK19765.1 - 2.1e-31 109.1 0.3 2.6e-31 108.8 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KKK19765.1 - 0.0002 21.3 0.1 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_8 PF13450.1 KKK19765.1 - 0.031 14.3 0.1 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK19765.1 - 0.039 14.3 0.1 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK19765.1 - 0.096 11.7 0.2 0.26 10.3 0.1 1.7 2 0 0 2 2 2 0 Thi4 family SOG2 PF10428.4 KKK19766.1 - 1.4 7.5 11.9 1.6 7.2 8.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 KKK19766.1 - 1.6 6.9 7.6 1.8 6.7 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Herpes_TAF50 PF03326.8 KKK19766.1 - 6.3 5.6 13.5 7.4 5.3 9.3 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Podoplanin PF05808.6 KKK19767.1 - 0.0016 18.0 0.1 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Podoplanin Pkinase PF00069.20 KKK19768.1 - 6.4e-36 123.8 0.0 1.8e-22 79.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19768.1 - 8.6e-20 70.8 0.0 1.1e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KKK19768.1 - 0.012 14.6 0.0 0.22 10.4 0.0 2.7 3 0 0 3 3 3 0 Kinase-like FXa_inhibition PF14670.1 KKK19768.1 - 0.082 13.0 0.5 0.17 12.0 0.3 1.5 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Syja_N PF02383.13 KKK19769.1 - 5.2e-93 311.3 0.1 1e-92 310.3 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DUF2454 PF10521.4 KKK19770.1 - 5.5e-96 320.8 0.5 7.9e-96 320.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) DUF3385 PF11865.3 KKK19770.1 - 0.15 11.9 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) PolyA_pol PF01743.15 KKK19771.1 - 4.7e-23 81.7 0.2 1.1e-22 80.6 0.1 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KKK19771.1 - 6.3e-07 28.8 0.0 1.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 KKK19771.1 - 0.0009 19.0 0.1 0.0026 17.6 0.0 1.8 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.2 KKK19772.1 - 2.8e-117 391.8 0.0 4.2e-117 391.2 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Abhydrolase_4 PF08386.5 KKK19773.1 - 1.9e-18 66.2 0.0 5.5e-18 64.7 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_6 PF12697.2 KKK19773.1 - 6e-10 39.3 0.1 2.9e-09 37.1 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK19773.1 - 7.5e-08 32.2 0.0 1.4e-06 28.0 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK19773.1 - 0.00033 20.4 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2920 PF11144.3 KKK19773.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) CytadhesinP1 PF12378.3 KKK19774.1 - 0.067 13.1 0.1 0.07 13.0 0.1 1.1 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein DNA_pol_B PF00136.16 KKK19775.1 - 5.1e-146 487.1 3.9 7e-146 486.6 2.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KKK19775.1 - 1.2e-83 280.6 0.1 2.9e-83 279.4 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KKK19775.1 - 1.6e-24 85.6 4.9 3.6e-24 84.5 3.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KKK19775.1 - 5.6e-05 23.0 0.3 0.00027 20.7 0.2 2.3 1 1 0 1 1 1 1 RNase_H superfamily DUF1395 PF07160.7 KKK19776.1 - 0.022 14.2 0.8 0.034 13.6 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) DUF3661 PF12400.3 KKK19783.1 - 3e-42 143.7 4.0 5.5e-42 142.9 2.8 1.5 1 0 0 1 1 1 1 Vaculolar membrane protein RRM_1 PF00076.17 KKK19783.1 - 3.1e-18 65.1 0.3 4.9e-18 64.5 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK19783.1 - 3.9e-13 49.1 0.1 6.8e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK19783.1 - 6.1e-09 35.6 0.1 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pam16 PF03656.8 KKK19784.1 - 3.1e-35 120.7 0.5 3.9e-35 120.4 0.3 1.0 1 0 0 1 1 1 1 Pam16 PAP_assoc PF03828.14 KKK19785.1 - 4.6e-16 58.4 0.3 9.4e-16 57.5 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KKK19785.1 - 7.7e-09 35.7 0.0 2.2e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pex24p PF06398.6 KKK19786.1 - 7.3e-99 330.9 1.0 1e-98 330.4 0.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Fungal_trans_2 PF11951.3 KKK19787.1 - 6.3e-20 71.1 0.3 7.6e-20 70.8 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.7 KKK19788.1 - 4.8e-21 74.5 0.8 7.8e-21 73.8 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK19788.1 - 2.9e-17 62.4 0.1 4.9e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 KKK19788.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_N_assoc PF13823.1 KKK19788.1 - 0.0055 16.3 0.2 0.012 15.2 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.14 KKK19788.1 - 0.021 13.9 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KKK19788.1 - 0.047 13.7 0.1 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK19788.1 - 0.097 12.5 0.3 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thiolase_C PF02803.13 KKK19789.1 - 2.5e-11 43.0 0.5 7.1e-11 41.5 0.4 1.8 1 1 0 1 1 1 1 Thiolase, C-terminal domain DUF3208 PF11482.3 KKK19789.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) BRO1 PF03097.13 KKK19790.1 - 2e-117 392.1 0.0 2e-117 392.1 0.0 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KKK19790.1 - 3.3e-67 226.5 19.1 8.5e-34 116.8 7.9 2.4 1 1 1 2 2 2 2 ALIX V-shaped domain binding to HIV Mito_carr PF00153.22 KKK19790.1 - 5.7e-43 144.5 1.3 1.4e-15 56.7 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 KKK19791.1 - 7.5e-14 51.1 0.0 1.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK19791.1 - 3.6e-10 39.6 0.0 6.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK19791.1 - 3.3e-09 36.4 0.1 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.4 KKK19791.1 - 4.1 5.9 16.7 0.46 9.0 0.2 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein SMN PF06003.7 KKK19792.1 - 3.6e-06 26.2 6.9 0.00063 18.9 1.7 2.3 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) DUF2890 PF11081.3 KKK19792.1 - 0.072 13.1 1.9 0.075 13.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) PH PF00169.24 KKK19825.1 - 2.7e-11 43.5 0.2 9.6e-11 41.8 0.1 2.0 1 0 0 1 1 1 1 PH domain RRM_1 PF00076.17 KKK19826.1 - 1.3e-45 152.8 0.0 6.2e-17 60.9 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK19826.1 - 9.9e-39 131.1 0.0 1.5e-15 56.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK19826.1 - 3.6e-23 81.1 0.0 2.5e-07 30.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KKK19826.1 - 0.0003 20.4 0.2 3.7 7.3 0.0 4.2 3 2 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.5 KKK19826.1 - 0.01 15.2 0.0 0.084 12.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain RRM_3 PF08777.6 KKK19826.1 - 0.024 14.4 0.0 5.7 6.8 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif PknH_C PF14032.1 KKK19826.1 - 0.035 13.6 0.6 31 4.0 0.0 3.2 3 0 0 3 3 3 0 PknH-like extracellular domain COQ9 PF08511.6 KKK19827.1 - 3.1e-26 90.7 0.1 5.6e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 COQ9 K_channel_TID PF07941.6 KKK19828.1 - 7.5 6.8 9.8 13 6.0 0.6 2.9 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.27 KKK19829.1 - 1.2e-15 56.6 0.5 0.00034 20.3 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Palm_thioest PF02089.10 KKK19830.1 - 1.6e-61 207.6 0.0 2.1e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 KKK19830.1 - 0.0011 18.9 0.0 0.0028 17.5 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 KKK19830.1 - 0.0048 16.0 0.0 0.0088 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 KKK19830.1 - 0.032 13.7 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KKK19830.1 - 0.072 12.5 0.1 7.9 5.8 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Med31 PF05669.7 KKK19832.1 - 4.4e-30 103.4 0.0 5.4e-30 103.1 0.0 1.1 1 0 0 1 1 1 1 SOH1 Tcf25 PF04910.9 KKK19832.1 - 0.028 13.3 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Alk_phosphatase PF00245.15 KKK19833.1 - 1.8e-60 204.8 0.0 4.1e-60 203.6 0.0 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 KKK19833.1 - 1.1e-06 28.0 0.7 4.6e-06 26.0 0.5 2.1 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KKK19833.1 - 7.9e-06 25.4 0.2 1.5e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase FTA4 PF13093.1 KKK19833.1 - 0.00078 18.9 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF229 PF02995.12 KKK19833.1 - 0.0022 16.4 0.1 0.0039 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) HHH_3 PF12836.2 KKK19833.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Metalloenzyme PF01676.13 KKK19833.1 - 0.061 12.7 0.5 0.12 11.6 0.3 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Peptidase_C16 PF01831.12 KKK19833.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase C16 family Terpene_synth_C PF03936.11 KKK19851.1 - 0.00042 19.6 0.2 0.00067 18.9 0.2 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 KKK19852.1 - 1e-50 172.6 0.0 1.5e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KKK19853.1 - 3.8e-39 134.3 51.1 3.8e-39 134.3 35.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK19853.1 - 2.5e-05 23.0 41.8 6.8e-05 21.6 29.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 KKK19854.1 - 8.7e-112 373.9 25.3 1e-111 373.7 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK19854.1 - 1.3e-22 79.9 25.3 1.3e-22 79.9 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_2 PF02230.11 KKK19855.1 - 1.2e-27 96.7 0.0 3.6e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KKK19855.1 - 5e-06 26.5 1.1 2e-05 24.6 0.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK19855.1 - 1.8e-05 24.4 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 KKK19855.1 - 0.093 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Peptidase_S9 PF00326.16 KKK19855.1 - 0.14 11.3 0.0 1.5 7.9 0.0 2.3 3 0 0 3 3 3 0 Prolyl oligopeptidase family AA_permease PF00324.16 KKK19856.1 - 1e-114 383.5 47.5 1.1e-114 383.3 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK19856.1 - 1.9e-41 142.0 49.7 2.7e-41 141.5 34.4 1.3 1 0 0 1 1 1 1 Amino acid permease EB PF01683.13 KKK19857.1 - 9.8 6.3 21.6 8 6.6 3.4 2.4 1 1 1 2 2 2 0 EB module p450 PF00067.17 KKK19858.1 - 6.2e-71 239.2 0.0 7.2e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PRANC PF09372.5 KKK19859.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 PRANC domain MFS_1 PF07690.11 KKK19861.1 - 1.9e-09 36.7 16.4 1e-06 27.7 4.8 3.7 3 1 1 4 4 4 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK19861.1 - 2.5e-05 22.6 1.0 2.5e-05 22.6 0.7 2.6 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK19861.1 - 7.7e-05 21.4 2.7 7.7e-05 21.4 1.8 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Glyco_hydro_75 PF07335.6 KKK19862.1 - 5.7e-42 143.2 0.0 9.1e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 EB PF01683.13 KKK19862.1 - 1.1 9.4 26.6 40 4.3 8.8 3.1 2 1 1 3 3 3 0 EB module Malic_M PF03949.10 KKK19863.1 - 7.1e-80 268.2 0.0 1.2e-79 267.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KKK19863.1 - 4.2e-64 215.4 0.2 9.9e-64 214.2 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain GPI-anchored PF10342.4 KKK19864.1 - 0.054 13.9 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_1 PF07690.11 KKK19865.1 - 1.9e-40 138.6 32.7 1.9e-40 138.6 22.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK19865.1 - 1.2e-14 53.8 6.3 1.2e-14 53.8 4.4 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.13 KKK19865.1 - 3.3e-06 26.8 10.6 7.2e-06 25.8 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_3 PF05977.8 KKK19865.1 - 0.0014 16.8 0.5 0.0027 15.9 0.4 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector E1-E2_ATPase PF00122.15 KKK19866.1 - 1.1e-52 178.3 2.1 2.1e-52 177.4 1.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK19866.1 - 8.1e-38 129.7 2.9 8.1e-38 129.7 2.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK19866.1 - 2.8e-31 109.6 0.0 2.2e-30 106.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK19866.1 - 1e-19 70.2 0.0 1.9e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK19866.1 - 5.8e-16 59.2 0.0 1.8e-15 57.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK19866.1 - 2.4e-11 42.9 0.0 6.8e-11 41.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK19866.1 - 4.3e-05 23.2 0.2 8.1e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1625 PF07787.7 KKK19866.1 - 0.023 13.9 1.2 2.5 7.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) DUF2207 PF09972.4 KKK19866.1 - 3.7 6.0 3.4 4.3 5.7 0.0 2.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) SnoaL_4 PF13577.1 KKK19867.1 - 1.2e-05 25.2 0.2 1.4e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 KKK19867.1 - 0.0002 21.6 0.2 0.00025 21.4 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KKK19867.1 - 0.015 15.3 0.3 0.019 14.9 0.2 1.2 1 0 0 1 1 1 0 SnoaL-like domain ZipA_C PF04354.8 KKK19867.1 - 0.069 12.6 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain NTF2 PF02136.15 KKK19867.1 - 0.076 13.3 0.1 0.098 13.0 0.1 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain MFS_1 PF07690.11 KKK19868.1 - 6e-06 25.2 1.9 0.00017 20.3 1.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK19868.1 - 0.007 14.6 0.8 0.0081 14.4 0.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KKK19868.1 - 0.0083 14.2 1.5 0.013 13.6 0.6 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector PUCC PF03209.10 KKK19868.1 - 0.014 14.1 0.6 0.036 12.7 0.4 1.5 1 1 0 1 1 1 0 PUCC protein MFS_1 PF07690.11 KKK19869.1 - 3.7e-06 25.8 27.3 1.2e-05 24.1 19.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Cytomega_TRL10 PF06084.6 KKK19869.1 - 0.015 15.0 1.8 0.12 12.1 0.1 2.4 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Mtp PF03821.11 KKK19869.1 - 0.099 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Esterase PF00756.15 KKK19870.1 - 6.4e-10 38.8 0.0 1.9e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KKK19870.1 - 0.00075 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KKK19870.1 - 0.0033 17.3 0.1 0.0046 16.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DEAD PF00270.24 KKK19871.1 - 6e-46 156.0 0.0 5e-45 153.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK19871.1 - 2.9e-27 94.3 0.1 5.8e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK19871.1 - 0.027 14.3 0.0 0.066 13.0 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_M16 PF00675.15 KKK19871.1 - 0.11 12.2 0.0 8.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) CMS1 PF14617.1 KKK19871.1 - 0.18 10.8 0.1 0.32 10.0 0.1 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 KKK19871.1 - 0.25 9.7 0.0 0.45 8.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) INSIG PF07281.7 KKK19873.1 - 9.7e-86 286.0 0.9 1.2e-85 285.7 0.6 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) WD40 PF00400.27 KKK19874.1 - 4.5e-22 77.0 19.1 3.4e-07 29.9 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 KKK19874.1 - 7.4e-21 73.9 0.2 2.5e-20 72.2 0.1 2.1 2 0 0 2 2 2 1 NLE (NUC135) domain Zw10 PF06248.8 KKK19874.1 - 8.5e-17 60.5 1.3 1.2e-14 53.4 0.2 2.2 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KKK19874.1 - 1e-07 31.4 0.1 2.4e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Ribosomal_S13 PF00416.17 KKK19875.1 - 1.5e-20 73.6 0.0 1.7e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 KKK19876.1 - 1.5e-45 155.2 0.3 2e-45 154.7 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bromodomain PF00439.20 KKK19877.1 - 2e-26 91.6 0.2 4.2e-26 90.6 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KKK19877.1 - 1.6e-09 37.7 0.1 4e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK19877.1 - 1.6e-08 34.4 0.0 3.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Peptidase_M16_C PF05193.16 KKK19878.1 - 2.7e-18 66.2 0.0 1.6e-13 50.7 0.0 2.9 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KKK19878.1 - 2.1e-05 24.3 0.0 8.4e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) TFIIA PF03153.8 KKK19878.1 - 0.0029 17.5 15.7 0.0045 16.9 10.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Astro_capsid PF03115.9 KKK19878.1 - 0.52 8.4 4.6 0.8 7.8 3.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Cwf_Cwc_15 PF04889.7 KKK19878.1 - 4.4 6.9 23.2 0.29 10.8 11.3 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 KKK19878.1 - 6.4 4.6 21.7 9.6 4.0 15.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SSrecog PF03531.9 KKK19879.1 - 1.7e-68 230.3 0.1 1.7e-67 227.0 0.0 2.3 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KKK19879.1 - 1.6e-28 98.4 0.0 1.4e-27 95.4 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like BSP_II PF05432.6 KKK19879.1 - 3.9 6.6 26.6 5.6 6.1 12.0 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Asp PF00026.18 KKK19880.1 - 1.8e-28 99.7 0.7 2.4e-28 99.3 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK19880.1 - 0.027 14.4 0.1 0.11 12.4 0.0 2.1 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal FA_desaturase PF00487.19 KKK19881.1 - 8.6e-38 130.2 30.2 1.3e-37 129.6 20.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KKK19881.1 - 5.8e-10 38.8 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pro_isomerase PF00160.16 KKK19882.1 - 2.3e-41 141.5 0.0 3.8e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 KKK19882.1 - 9.8e-06 24.9 0.1 3.5e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 KKK19882.1 - 0.00048 20.0 0.6 0.0058 16.5 0.0 2.8 2 1 0 3 3 3 1 U-box domain GTP_EFTU PF00009.22 KKK19883.1 - 1.9e-54 183.9 0.0 3e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KKK19883.1 - 1.5e-08 34.6 0.0 6e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KKK19883.1 - 6.9e-08 32.2 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KKK19883.1 - 0.0014 18.2 0.0 0.057 12.9 0.0 2.6 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 KKK19883.1 - 0.017 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4604 PF15377.1 KKK19884.1 - 1.2e-24 87.2 15.1 1.7e-24 86.7 10.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Prp19 PF08606.6 KKK19885.1 - 4.1e-33 112.9 1.8 6.8e-33 112.2 1.3 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KKK19885.1 - 3.2e-15 55.3 0.1 8.6e-06 25.4 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KKK19885.1 - 1.5e-08 33.8 0.2 9.2e-06 24.7 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 KKK19885.1 - 1.2e-05 25.1 0.1 0.0088 15.7 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.10 KKK19885.1 - 0.00047 20.0 0.0 0.00095 19.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain PQQ_2 PF13360.1 KKK19885.1 - 0.0024 17.3 8.6 0.011 15.2 1.2 2.4 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.16 KKK19885.1 - 0.11 12.1 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat DUF3312 PF11768.3 KKK19885.1 - 0.26 9.4 0.0 0.82 7.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) L51_S25_CI-B8 PF05047.11 KKK19886.1 - 4.9e-15 55.0 0.1 8.4e-15 54.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 KKK19887.1 - 4.2e-33 113.5 3.7 8.6e-33 112.5 2.6 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KKK19887.1 - 6e-12 45.0 0.0 1.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK19887.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK19887.1 - 0.0031 17.3 0.0 0.0099 15.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KKK19887.1 - 3.9 7.1 36.4 30 4.3 25.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) AAA PF00004.24 KKK19888.1 - 2.4e-07 30.9 0.1 0.00082 19.5 0.0 2.4 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK19888.1 - 5.4e-06 26.5 0.0 9.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 KKK19888.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KKK19888.1 - 0.084 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus F-box-like PF12937.2 KKK19889.1 - 0.00031 20.3 0.2 0.00073 19.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like PalH PF08733.5 KKK19890.1 - 1.5e-104 349.6 0.0 5e-104 347.8 0.0 1.7 1 1 0 1 1 1 1 PalH/RIM21 Asp PF00026.18 KKK19892.1 - 4.3e-71 239.7 6.3 6e-71 239.2 4.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KKK19892.1 - 2.1e-07 31.3 0.8 0.021 15.2 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KKK19892.1 - 3.6e-05 23.7 0.0 0.0011 18.9 0.0 2.7 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KKK19892.1 - 0.0038 16.7 0.0 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Triabin PF03973.8 KKK19892.1 - 0.032 13.8 0.1 0.09 12.4 0.0 1.7 1 1 1 2 2 2 0 Triabin PPC PF04151.10 KKK19892.1 - 3 8.8 11.4 3.4 8.7 2.3 3.1 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain PLAC8 PF04749.12 KKK19893.1 - 4.7e-22 78.5 17.4 6.1e-22 78.1 12.1 1.1 1 0 0 1 1 1 1 PLAC8 family PAT1 PF09770.4 KKK19893.1 - 8.4 4.4 9.3 10 4.2 6.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_C13 PF01650.13 KKK19894.1 - 0.0025 17.1 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family UBA PF00627.26 KKK19894.1 - 0.0041 16.9 0.2 0.071 12.9 0.1 2.8 3 0 0 3 3 3 1 UBA/TS-N domain ABC_membrane_3 PF13748.1 KKK19894.1 - 0.058 12.4 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Glycos_transf_1 PF00534.15 KKK19895.1 - 7e-31 106.9 0.5 3e-29 101.6 0.4 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 ERCC4 PF02732.10 KKK19895.1 - 8.3e-27 93.7 0.1 2.1e-26 92.3 0.0 1.8 2 0 0 2 2 2 1 ERCC4 domain Glyco_transf_4 PF13439.1 KKK19895.1 - 2.3e-10 40.5 0.0 0.00015 21.5 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KKK19895.1 - 5e-08 33.1 0.0 3.7e-06 27.1 0.0 2.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KKK19895.1 - 1.8e-07 31.4 0.9 0.0059 16.7 0.2 2.9 3 0 0 3 3 3 2 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KKK19895.1 - 0.00017 21.7 0.0 0.00059 20.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 SAPS PF04499.10 KKK19895.1 - 0.066 11.8 1.1 0.11 11.1 0.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mhr1 PF12829.2 KKK19896.1 - 3.7e-32 109.9 0.3 8.8e-32 108.7 0.2 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DDHD PF02862.12 KKK19896.1 - 0.086 12.6 0.7 0.13 12.0 0.5 1.3 1 0 0 1 1 1 0 DDHD domain IPK PF03770.11 KKK19897.1 - 7.4e-61 205.2 0.0 1.3e-60 204.4 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 KKK19897.1 - 0.038 13.7 0.1 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.11 KKK19898.1 - 1.4e-18 66.7 12.4 1.4e-18 66.7 8.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KKK19898.1 - 2.1e-09 37.0 1.0 2.1e-09 37.0 0.7 1.8 2 0 0 2 2 2 1 Nodulin-like PVL_ORF50 PF07768.6 KKK19898.1 - 0.84 9.6 5.6 0.1 12.6 0.8 1.8 2 0 0 2 2 2 0 PVL ORF-50-like family Atg14 PF10186.4 KKK19899.1 - 1.3e-25 89.9 0.1 2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KKK19899.1 - 7.6e-07 28.4 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 BRE1 PF08647.6 KKK19899.1 - 0.099 12.6 4.6 0.18 11.7 3.2 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Exonuc_VII_L PF02601.10 KKK19899.1 - 0.21 10.7 2.9 0.31 10.1 2.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YjeF_N PF03853.10 KKK19900.1 - 1.8e-37 128.5 0.1 2.5e-37 128.1 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KKK19900.1 - 4.1e-12 46.5 1.5 7.2e-12 45.7 1.0 1.4 1 0 0 1 1 1 1 FDF domain Glyco_transf_4 PF13439.1 KKK19900.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 NTP_transferase PF00483.18 KKK19900.1 - 0.064 12.5 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Nucleotidyl transferase PP2C PF00481.16 KKK19901.1 - 2.2e-62 210.7 0.1 3.8e-50 170.6 0.2 3.1 3 0 0 3 3 3 2 Protein phosphatase 2C DUF1180 PF06679.7 KKK19901.1 - 0.0078 16.1 2.3 0.01 15.6 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) DEC-1_N PF04625.8 KKK19901.1 - 0.024 13.3 0.4 0.024 13.3 0.2 1.5 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region PAT1 PF09770.4 KKK19902.1 - 0.25 9.5 11.4 0.34 9.0 7.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TIM PF00121.13 KKK19903.1 - 6.7e-90 300.4 0.6 7.5e-90 300.2 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DeoRC PF00455.17 KKK19903.1 - 0.0015 18.2 0.5 0.83 9.2 0.1 2.9 1 1 1 3 3 3 2 DeoR C terminal sensor domain CutC PF03932.9 KKK19903.1 - 0.036 13.3 0.1 0.059 12.6 0.1 1.4 1 0 0 1 1 1 0 CutC family START PF01852.14 KKK19903.1 - 0.088 12.1 0.1 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 START domain Dynamin_N PF00350.18 KKK19904.1 - 2.9e-16 59.7 0.0 5.9e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KKK19904.1 - 8.8e-10 38.5 0.0 4.2e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK19904.1 - 3.5e-06 26.5 0.6 4.7e-05 22.9 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KKK19904.1 - 0.015 15.8 0.4 0.72 10.3 0.1 3.3 3 1 0 3 3 3 0 Miro-like protein AAA_17 PF13207.1 KKK19904.1 - 0.027 15.3 0.2 0.59 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KKK19904.1 - 0.029 14.6 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KKK19904.1 - 0.05 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Snf7 PF03357.16 KKK19905.1 - 3.1e-35 121.0 15.9 6.2e-35 120.0 10.8 1.5 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 KKK19905.1 - 0.011 13.6 2.5 0.013 13.3 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 KKK19905.1 - 0.058 12.7 5.1 0.083 12.2 3.6 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.3 KKK19905.1 - 9.5 6.2 17.2 7.6 6.5 7.2 2.1 1 1 1 2 2 2 0 YlqD protein Zn_clus PF00172.13 KKK19906.1 - 3.9e-08 33.0 8.7 3.9e-08 33.0 6.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PTCB-BRCT PF12738.2 KKK19907.1 - 3.4e-24 84.4 2.8 7.5e-11 41.7 0.0 4.5 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.21 KKK19907.1 - 2.4e-17 62.8 1.0 5.8e-07 29.5 0.0 4.4 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain PIF1 PF05970.9 KKK19908.1 - 3.2e-64 217.1 0.0 1.6e-49 168.8 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KKK19908.1 - 1.7e-18 66.9 0.0 3.4e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KKK19908.1 - 1.6e-07 31.5 0.0 5e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KKK19908.1 - 1.9e-05 24.7 0.2 0.00026 21.1 0.1 2.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KKK19908.1 - 4.3e-05 23.5 0.5 0.0028 17.6 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain Herpes_Helicase PF02689.9 KKK19908.1 - 9.7e-05 20.3 0.1 0.00054 17.8 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.1 KKK19908.1 - 0.00014 21.5 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 KKK19908.1 - 0.00027 19.9 0.0 0.00055 18.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 KKK19908.1 - 0.00081 18.4 1.6 0.0075 15.2 0.0 2.6 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KKK19908.1 - 0.0043 17.2 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 KKK19908.1 - 0.0066 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KKK19908.1 - 0.008 15.4 0.0 0.035 13.3 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein TrwB_AAD_bind PF10412.4 KKK19908.1 - 0.0089 14.6 0.0 0.017 13.7 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain UvrD-helicase PF00580.16 KKK19908.1 - 0.0099 15.2 0.7 0.014 14.6 0.0 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Arch_ATPase PF01637.13 KKK19908.1 - 0.011 15.4 0.2 0.035 13.8 0.2 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_11 PF13086.1 KKK19908.1 - 0.014 14.9 3.3 0.029 13.9 0.0 2.8 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.17 KKK19908.1 - 0.015 14.2 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 KKK19908.1 - 0.017 15.0 0.0 0.062 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KKK19908.1 - 0.018 14.5 0.2 9.4 5.6 0.1 3.0 3 1 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KKK19908.1 - 0.041 14.1 0.3 0.82 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KKK19908.1 - 0.043 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 KKK19908.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 KKK19908.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.2 KKK19908.1 - 0.081 11.9 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 AAA_25 PF13481.1 KKK19908.1 - 0.097 12.0 0.0 0.82 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KKK19908.1 - 0.12 12.1 0.4 1.3 8.6 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KKK19908.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_L10 PF00466.15 KKK19909.1 - 1e-18 67.1 0.0 2.1e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3722 PF12519.3 KKK19911.1 - 2.1e-83 279.5 5.5 2.9e-83 279.0 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Thioredoxin PF00085.15 KKK19912.1 - 1.7e-28 98.3 0.0 2.4e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KKK19912.1 - 1.7e-08 34.4 0.0 3.3e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KKK19912.1 - 7.6e-08 32.5 0.1 4.4e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KKK19912.1 - 7.1e-05 22.3 0.0 9.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KKK19912.1 - 7.2e-05 22.3 0.3 0.00092 18.7 0.1 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 KKK19912.1 - 0.00011 21.9 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KKK19912.1 - 0.002 18.1 0.1 0.0045 16.9 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 KKK19912.1 - 0.0093 15.4 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Phosducin PF02114.11 KKK19912.1 - 0.049 12.3 0.0 0.063 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_4 PF13462.1 KKK19912.1 - 0.09 12.7 0.0 3.4 7.6 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Aldo_ket_red PF00248.16 KKK19913.1 - 6.8e-55 185.8 0.0 7.6e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 KKK19914.1 - 1.9e-25 89.7 0.2 2.8e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK19914.1 - 9.8e-20 71.3 0.5 1.7e-19 70.5 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK19914.1 - 2e-10 40.5 0.2 2.9e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KKK19914.1 - 0.00067 18.6 0.0 0.00086 18.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KKK19914.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ank_2 PF12796.2 KKK19915.1 - 9.1e-73 240.6 0.4 3.1e-17 62.6 0.2 5.6 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK19915.1 - 3.1e-55 183.6 1.3 2.9e-09 37.1 0.0 8.0 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.25 KKK19915.1 - 3.1e-51 168.7 0.1 0.00098 18.8 0.1 12.2 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 KKK19915.1 - 2e-44 148.6 0.8 4.3e-07 29.9 0.0 9.2 2 2 8 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK19915.1 - 3.2e-43 141.3 0.0 0.00078 19.4 0.0 12.4 12 0 0 12 12 12 9 Ankyrin repeat Aa_trans PF01490.13 KKK19915.1 - 5.7e-39 133.7 32.0 7.8e-39 133.3 22.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein F-box-like PF12937.2 KKK19915.1 - 1.7e-06 27.6 0.1 6.6e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK19915.1 - 0.00011 21.7 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain DUF2678 PF10856.3 KKK19915.1 - 8.1 6.2 7.9 6.2 6.5 1.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) Acetyltransf_3 PF13302.1 KKK19916.1 - 2e-14 53.9 0.0 3.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK19916.1 - 5.3e-08 32.7 0.0 7.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KKK19916.1 - 8.6e-07 29.0 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KKK19916.1 - 0.00012 21.9 0.5 0.00062 19.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PG_binding_2 PF08823.6 KKK19916.1 - 0.13 12.3 1.5 0.52 10.4 0.5 2.2 2 0 0 2 2 2 0 Putative peptidoglycan binding domain NACHT PF05729.7 KKK19917.1 - 6.8e-11 42.1 0.1 2.1e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KKK19917.1 - 5.1e-09 36.3 1.1 3.7e-08 33.5 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 KKK19917.1 - 4.2e-07 29.9 0.1 7.5e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 KKK19917.1 - 1.5e-06 28.3 1.6 0.00021 21.4 0.0 3.5 3 1 1 4 4 4 1 AAA domain NB-ARC PF00931.17 KKK19917.1 - 5.8e-05 22.0 0.0 0.00016 20.6 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 KKK19917.1 - 0.00046 20.4 0.0 0.0016 18.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KKK19917.1 - 0.0014 18.3 0.1 0.0036 16.9 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 KKK19917.1 - 0.011 16.5 0.3 0.066 14.0 0.1 2.7 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KKK19917.1 - 0.024 14.9 0.1 0.27 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KKK19917.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 KKK19917.1 - 0.067 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KKK19917.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 KKK19917.1 - 0.22 10.4 7.1 0.15 11.0 0.5 2.8 2 1 1 3 3 3 0 KAP family P-loop domain Fungal_trans PF04082.13 KKK19918.1 - 6.3e-10 38.3 0.7 1e-09 37.6 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19918.1 - 7.3e-08 32.2 7.1 1.2e-07 31.4 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alba PF01918.16 KKK19918.1 - 0.22 11.1 0.1 1 8.9 0.0 2.0 2 0 0 2 2 2 0 Alba MFS_1 PF07690.11 KKK19919.1 - 1.1e-35 123.0 67.1 3e-25 88.6 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B_N_2 PF13631.1 KKK19919.1 - 0.014 15.2 2.4 0.014 15.2 1.6 3.1 2 1 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB MFS_1_like PF12832.2 KKK19919.1 - 0.025 14.3 0.7 0.025 14.3 0.5 3.2 3 2 2 5 5 5 0 MFS_1 like family Pox_A9 PF04835.7 KKK19919.1 - 0.32 10.9 2.8 0.29 11.0 0.3 2.2 2 0 0 2 2 2 0 A9 protein conserved region DUF3681 PF12442.3 KKK19919.1 - 7.4 6.8 10.5 1.2 9.3 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3681) Pyr_redox_2 PF07992.9 KKK19920.1 - 1.6e-11 44.4 0.0 3.9e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK19920.1 - 9.3e-09 35.5 0.0 2.9e-06 27.6 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK19920.1 - 3.5e-05 23.9 0.2 0.04 13.9 0.0 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK19920.1 - 0.00014 20.8 1.4 0.78 8.5 0.1 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase DUF2937 PF11157.3 KKK19920.1 - 0.077 12.3 0.7 0.99 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) K_oxygenase PF13434.1 KKK19920.1 - 0.16 10.8 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Prenyltrans_2 PF13249.1 KKK19921.1 - 1.6e-39 134.8 4.3 1.3e-17 64.1 0.0 5.6 3 2 2 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KKK19921.1 - 1e-30 105.9 0.1 5.9e-15 55.2 0.0 5.6 5 1 0 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 KKK19921.1 - 8.9e-19 66.7 14.2 6.8e-06 25.5 0.0 6.5 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 KKK19921.1 - 2.5e-06 26.8 0.2 0.052 12.7 0.0 3.5 3 1 0 3 3 3 2 Pectic acid lyase A2M_comp PF07678.9 KKK19921.1 - 0.0015 17.8 0.1 4.7 6.3 0.0 3.9 4 1 1 5 5 5 2 A-macroglobulin complement component Transket_pyr PF02779.19 KKK19922.1 - 3e-42 144.1 0.2 4.2e-42 143.6 0.2 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KKK19922.1 - 3.2e-08 33.5 0.0 0.005 16.7 0.0 2.6 1 1 1 2 2 2 2 Transketolase, C-terminal domain Arylsulfotran_2 PF14269.1 KKK19923.1 - 3.5e-58 197.1 0.3 4.9e-58 196.6 0.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KKK19923.1 - 7.4e-17 61.0 2.6 1.6e-16 59.9 1.8 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) RCC1 PF00415.13 KKK19934.1 - 3.4e-39 132.8 10.7 5.5e-09 36.1 0.2 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KKK19934.1 - 1.8e-29 100.6 34.5 1.4e-09 37.3 0.5 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 KKK19934.1 - 0.00063 19.1 4.4 12 5.4 0.0 5.5 6 0 0 6 6 6 2 Putative carbohydrate binding domain DHDPS PF00701.17 KKK19949.1 - 1.2e-47 161.9 0.0 1.3e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SAS4 PF15460.1 KKK19950.1 - 4.1e-34 116.4 11.5 8.8e-34 115.4 7.9 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Clr5 PF14420.1 KKK19951.1 - 1.5e-19 69.5 2.6 2.5e-19 68.9 1.8 1.3 1 0 0 1 1 1 1 Clr5 domain Trypan_PARP PF05887.6 KKK19951.1 - 4 7.2 7.6 0.88 9.3 2.9 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SKG6 PF08693.5 KKK19952.1 - 0.0012 18.1 0.4 0.0037 16.5 0.3 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 KKK19952.1 - 0.011 15.5 3.3 0.011 15.5 2.3 2.0 2 0 0 2 2 2 0 Glycophorin A Sporozoite_P67 PF05642.6 KKK19952.1 - 0.19 9.5 11.4 0.28 8.9 7.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Podoplanin PF05808.6 KKK19952.1 - 0.21 11.1 10.2 0.086 12.3 5.3 1.6 1 1 1 2 2 2 0 Podoplanin Peroxin-13_N PF04088.8 KKK19953.1 - 7.7e-59 198.1 0.1 1.2e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KKK19953.1 - 1.3e-09 37.4 0.0 2.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK19953.1 - 1.7e-08 33.7 0.0 2.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK19953.1 - 6.7e-07 28.7 0.1 1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ERO1 PF04137.10 KKK19954.1 - 3.9e-137 457.0 0.0 5e-137 456.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pal1 PF08316.6 KKK19955.1 - 4.2e-10 40.2 0.0 6.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Pal1 cell morphology protein DUF3807 PF12720.2 KKK19956.1 - 2e-42 145.2 0.1 3.2e-42 144.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) HVSL PF09749.4 KKK19956.1 - 3.6e-27 94.9 0.1 5.2e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein MFS_1 PF07690.11 KKK19957.1 - 1.4e-25 89.7 65.3 2.3e-17 62.7 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KKK19957.1 - 0.0001 22.2 12.2 0.046 13.7 0.1 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF1228) MFS_2 PF13347.1 KKK19957.1 - 0.00019 19.9 16.5 0.00019 19.9 11.4 2.9 1 1 1 2 2 2 1 MFS/sugar transport protein Aa_trans PF01490.13 KKK19958.1 - 1.5e-43 148.8 35.1 1.8e-43 148.5 24.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0052 PF01933.13 KKK19980.1 - 7.2e-53 179.8 0.0 9.1e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Head-tail_con PF12236.3 KKK19980.1 - 0.18 10.1 0.0 0.25 9.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein DNA_pol_A PF00476.15 KKK19981.1 - 5e-99 331.4 0.0 7.1e-99 331.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Mad3_BUB1_I PF08311.7 KKK19981.1 - 0.038 13.7 0.5 0.087 12.6 0.3 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DNA_pol_A_exo1 PF01612.15 KKK19981.1 - 0.074 12.5 0.3 1.9 7.9 0.2 2.7 1 1 0 1 1 1 0 3'-5' exonuclease DltD_C PF04914.7 KKK19981.1 - 0.084 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 DltD C-terminal region DUF3414 PF11894.3 KKK19982.1 - 0 1626.3 15.1 0 1626.0 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) VP7 PF00434.13 KKK19982.1 - 0.1 11.4 0.3 0.38 9.6 0.5 1.6 2 0 0 2 2 2 0 Glycoprotein VP7 TAN PF11640.3 KKK19983.1 - 6.1e-52 175.4 2.5 2.7e-51 173.3 1.3 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair PI3_PI4_kinase PF00454.22 KKK19983.1 - 2.8e-45 154.6 0.0 5.4e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KKK19983.1 - 9.3e-13 47.3 0.7 5.8e-11 41.6 0.1 3.0 3 0 0 3 3 3 1 FATC domain DUF1353 PF07087.6 KKK19983.1 - 0.03 13.7 0.0 0.16 11.4 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Dak1 PF02733.12 KKK19984.1 - 1.7e-113 378.4 0.5 3.1e-113 377.6 0.3 1.4 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KKK19984.1 - 1.2e-44 152.0 0.2 2.4e-44 151.0 0.2 1.5 1 0 0 1 1 1 1 DAK2 domain Cullin PF00888.17 KKK19985.1 - 1.6e-118 396.8 0.0 1.9e-118 396.5 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KKK19985.1 - 2.9e-25 87.8 1.5 7.5e-25 86.5 1.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 KKK19985.1 - 0.00077 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 HbrB-like TrmB PF01978.14 KKK19985.1 - 0.026 14.2 0.1 4.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF605 PF04652.11 KKK19985.1 - 0.87 8.9 10.2 1.6 8.0 7.0 1.3 1 0 0 1 1 1 0 Vta1 like GATA PF00320.22 KKK19986.1 - 4.4e-06 25.9 4.3 0.00022 20.4 0.6 2.5 2 0 0 2 2 2 2 GATA zinc finger zf-C3HC4_3 PF13920.1 KKK19988.1 - 1.7e-10 40.4 6.2 2.6e-10 39.8 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK19988.1 - 1.2e-09 38.0 6.9 2.3e-09 37.1 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK19988.1 - 3.7e-09 36.0 4.6 8.4e-09 34.9 3.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK19988.1 - 8e-09 35.2 7.3 1.3e-08 34.4 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KKK19988.1 - 4.6e-08 32.6 7.4 8.7e-08 31.7 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KKK19988.1 - 1.2e-05 25.1 6.0 0.00011 22.0 4.4 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KKK19988.1 - 0.00039 20.0 6.7 0.0016 18.1 1.5 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 KKK19988.1 - 0.0012 18.3 0.4 0.0033 16.8 0.2 1.8 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.7 KKK19988.1 - 0.0046 17.0 7.0 0.029 14.4 0.9 2.3 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.9 KKK19988.1 - 0.026 13.9 1.7 0.61 9.6 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-H2C2_2 PF13465.1 KKK19988.1 - 0.026 14.7 1.9 1.7 9.1 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Prok-RING_4 PF14447.1 KKK19988.1 - 0.034 13.7 6.9 0.65 9.5 1.5 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 KKK19988.1 - 0.036 14.0 3.8 0.13 12.1 2.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.2 KKK19988.1 - 0.098 12.7 4.1 0.32 11.1 3.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KKK19988.1 - 0.16 11.5 7.3 0.67 9.5 5.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-4CXXC_R1 PF10497.4 KKK19988.1 - 0.38 10.9 3.4 1.2 9.3 2.4 1.8 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE PF01363.16 KKK19988.1 - 0.38 10.6 4.5 1 9.2 3.1 1.8 1 1 0 1 1 1 0 FYVE zinc finger zinc-ribbons_6 PF07191.7 KKK19988.1 - 1 9.1 4.6 52 3.7 3.2 2.3 1 1 0 1 1 1 0 zinc-ribbons zf-RING_6 PF14835.1 KKK19988.1 - 3.2 7.6 8.0 9.5 6.0 3.3 2.6 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 KKK19988.1 - 9.6 5.8 10.4 44 3.7 0.2 2.6 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger CorA PF01544.13 KKK19989.1 - 2.2e-27 95.8 9.9 8.5e-19 67.6 1.2 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DUF1143 PF06608.6 KKK19989.1 - 0.082 12.9 0.2 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) GTP_EFTU PF00009.22 KKK19990.1 - 1.1e-21 77.1 0.1 4.4e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KKK19990.1 - 2.3e-14 53.3 0.0 4.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KKK19990.1 - 2.3e-06 27.6 0.9 8.9e-06 25.7 0.7 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KKK19990.1 - 0.0011 18.4 0.7 0.18 11.2 0.1 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KKK19990.1 - 0.032 14.7 0.4 0.95 9.9 0.3 3.0 2 1 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 KKK19990.1 - 0.078 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase tRNA-synt_His PF13393.1 KKK19991.1 - 1.5e-38 132.6 0.0 3.1e-30 105.3 0.0 3.0 2 1 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KKK19991.1 - 7.1e-14 51.7 0.0 4.6e-08 32.8 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KKK19991.1 - 2.7e-11 43.2 0.0 5.5e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KKK19991.1 - 0.00076 18.3 0.0 1.1 7.9 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) SNF2_N PF00176.18 KKK19992.1 - 1.5e-68 230.8 0.0 2e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KKK19992.1 - 7.6e-22 77.2 0.0 1.6e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KKK19992.1 - 2.3e-14 52.9 0.0 8.9e-14 51.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KKK19992.1 - 1.1e-07 31.7 8.7 1.9e-07 30.9 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK19992.1 - 5.8e-05 22.6 5.1 0.00011 21.8 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK19992.1 - 0.00028 20.6 7.5 0.00052 19.7 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK19992.1 - 0.00037 20.0 8.1 0.00068 19.2 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK19992.1 - 0.0012 18.5 6.2 0.0023 17.6 4.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain UBA_4 PF14555.1 KKK19992.1 - 0.07 12.6 0.0 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain zf-C3HC4_4 PF15227.1 KKK19992.1 - 0.11 12.3 7.8 0.21 11.4 5.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KKK19992.1 - 0.13 12.0 5.5 0.32 10.7 3.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger SQS_PSY PF00494.14 KKK19993.1 - 7.9e-32 110.5 0.5 1.2e-31 110.0 0.1 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase DUF92 PF01940.11 KKK19993.1 - 0.064 12.4 0.2 0.24 10.4 0.1 1.8 2 0 0 2 2 2 0 Integral membrane protein DUF92 SQS_PSY PF00494.14 KKK19994.1 - 6.3e-09 35.5 0.1 8e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase TRAPP PF04051.11 KKK19995.1 - 1.4e-36 125.3 0.0 1.8e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.16 KKK19996.1 - 7.8e-65 218.4 0.0 1.1e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF2848 PF11010.3 KKK19996.1 - 0.015 14.7 0.1 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) DUF1583 PF07622.6 KKK19996.1 - 0.041 12.3 0.0 0.061 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) Rep_fac-A_3 PF08661.6 KKK19997.1 - 1.7e-23 82.5 0.0 1.9e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.2 KKK19997.1 - 0.1 12.3 0.0 1.2 8.8 0.0 2.0 1 1 0 1 1 1 0 Telomere capping, CST complex subunit Prp19_bind PF06991.6 KKK19998.1 - 3.6e-46 157.6 27.2 3.6e-46 157.6 18.8 3.1 3 0 0 3 3 3 2 Splicing factor, Prp19-binding domain NAD_binding_4 PF07993.7 KKK20000.1 - 6.2e-35 120.3 0.0 8.1e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KKK20000.1 - 3e-06 26.3 0.0 4.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KKK20000.1 - 0.014 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KKK20000.1 - 0.031 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 KR domain Zn_clus PF00172.13 KKK20001.1 - 2.4e-10 40.1 9.5 4.2e-10 39.3 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK20001.1 - 3.7e-05 22.5 0.8 5.4e-05 21.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_trans_1_4 PF13692.1 KKK20002.1 - 7.4e-29 100.6 0.0 1.4e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KKK20002.1 - 4.9e-07 29.3 0.0 7.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KKK20002.1 - 5e-06 26.7 0.0 9.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KKK20002.1 - 0.00091 19.3 0.1 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Cation_efflux PF01545.16 KKK20003.1 - 9.8e-53 179.0 11.1 9.8e-53 179.0 7.7 2.9 3 1 0 3 3 3 1 Cation efflux family Zip PF02535.17 KKK20003.1 - 6.3 5.6 63.9 0.076 12.0 5.4 4.9 3 1 2 5 5 5 0 ZIP Zinc transporter UQ_con PF00179.21 KKK20004.1 - 3.2e-51 172.4 0.0 3.6e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK20004.1 - 1.1e-05 25.1 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KKK20004.1 - 0.049 13.5 0.1 0.15 11.9 0.1 1.7 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 KKK20005.1 - 2.1e-111 371.8 0.0 4.8e-111 370.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain DinB_2 PF12867.2 KKK20005.1 - 0.29 11.4 0.0 0.29 11.4 0.0 3.2 4 2 0 4 4 4 0 DinB superfamily Reo_sigmaC PF04582.7 KKK20005.1 - 0.52 9.4 28.2 0.037 13.1 1.3 4.4 4 1 1 5 5 5 0 Reovirus sigma C capsid protein TFIIIC_delta PF12657.2 KKK20006.1 - 7e-47 159.3 1.3 9.5e-47 158.9 0.5 1.6 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 KKK20006.1 - 6.7e-31 106.1 1.7 1.3e-30 105.1 1.2 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex NCD3G PF07562.9 KKK20006.1 - 3.6 7.3 9.6 13 5.6 0.1 3.5 3 0 0 3 3 3 0 Nine Cysteines Domain of family 3 GPCR Shugoshin_N PF07558.6 KKK20007.1 - 4.3e-16 58.3 3.7 4.3e-16 58.3 2.5 1.8 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 KKK20007.1 - 3.1e-10 39.3 3.6 3.1e-10 39.3 2.5 3.0 2 0 0 2 2 2 1 Shugoshin C terminus DASH_Dad2 PF08654.5 KKK20008.1 - 5.7e-37 125.8 2.6 7.7e-37 125.4 1.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 NPV_P10 PF05531.7 KKK20008.1 - 0.00048 20.3 3.2 0.3 11.3 0.5 2.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 KKK20008.1 - 0.0059 16.6 2.7 0.0059 16.6 0.6 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Glutaredoxin2_C PF04399.8 KKK20008.1 - 0.1 12.1 0.7 0.15 11.6 0.5 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Prefoldin_2 PF01920.15 KKK20008.1 - 0.12 12.1 2.0 2.8 7.7 0.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit Phasin_2 PF09361.5 KKK20008.1 - 0.22 11.5 5.7 0.15 12.1 2.9 1.5 1 1 0 1 1 1 0 Phasin protein FTA4 PF13093.1 KKK20008.1 - 0.24 10.8 4.9 0.11 11.8 1.7 1.6 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FUSC PF04632.7 KKK20008.1 - 0.85 7.9 4.0 0.9 7.8 2.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family bZIP_1 PF00170.16 KKK20008.1 - 1.7 8.6 7.7 0.62 10.0 2.6 2.3 2 1 0 2 2 2 0 bZIP transcription factor FlxA PF14282.1 KKK20008.1 - 3.2 7.7 12.9 1.8 8.5 1.6 2.4 1 1 1 2 2 2 0 FlxA-like protein CRM1_C PF08767.6 KKK20009.1 - 1.3e-137 458.0 11.1 1.3e-137 458.0 7.7 2.9 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KKK20009.1 - 1.4e-42 145.1 10.5 4e-42 143.6 4.5 3.3 2 1 1 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KKK20009.1 - 0.0054 16.6 0.0 0.097 12.5 0.0 3.0 1 1 0 1 1 1 1 Importin-beta N-terminal domain HD_assoc PF13286.1 KKK20009.1 - 0.11 12.8 2.5 8.3 6.7 0.1 3.9 4 0 0 4 4 4 0 Phosphohydrolase-associated domain PPI_Ypi1 PF07491.6 KKK20010.1 - 2.9e-25 87.6 5.8 2.1e-24 84.9 4.0 2.3 1 1 0 1 1 1 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.7 KKK20010.1 - 0.015 13.6 10.4 0.016 13.6 7.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 KKK20010.1 - 0.096 10.7 7.7 0.12 10.4 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein CAF-1_p150 PF11600.3 KKK20010.1 - 5.6 6.2 13.7 9.4 5.5 9.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GIT_SHD PF08518.6 KKK20028.1 - 4.4e-22 77.1 8.3 1.3e-13 50.0 0.7 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT PspB PF06667.7 KKK20028.1 - 0.0023 17.7 0.4 0.0023 17.7 0.3 2.6 3 0 0 3 3 3 1 Phage shock protein B APG6 PF04111.7 KKK20028.1 - 2.7 6.9 33.0 0.011 14.8 8.1 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 Pro_isomerase PF00160.16 KKK20029.1 - 3.8e-23 82.4 0.0 4.9e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FA_desaturase PF00487.19 KKK20032.1 - 4e-26 92.0 17.7 7.1e-26 91.1 12.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KKK20032.1 - 1.6e-05 24.9 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) MARVEL PF01284.18 KKK20032.1 - 0.49 10.1 4.7 4.4 7.1 2.0 2.3 2 0 0 2 2 2 0 Membrane-associating domain LicD PF04991.8 KKK20033.1 - 8.6e-38 130.5 5.4 7.7e-37 127.4 3.7 2.1 1 1 0 1 1 1 1 LicD family UvrD-helicase PF00580.16 KKK20033.1 - 0.051 12.8 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Glyco_hydro_43 PF04616.9 KKK20034.1 - 1.3e-52 178.6 6.4 6e-29 101.0 0.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Pkinase PF00069.20 KKK20034.1 - 4.2e-11 42.5 0.0 1.2e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20034.1 - 6.7e-06 25.3 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK20034.1 - 0.0052 16.5 1.1 0.0052 16.5 0.7 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK20034.1 - 0.011 14.7 0.2 0.044 12.8 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KKK20034.1 - 0.021 13.7 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KKK20035.1 - 0.0002 21.1 0.0 0.00022 21.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family RRM_5 PF13893.1 KKK20036.1 - 0.032 14.0 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK20036.1 - 0.048 13.6 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FLO_LFY PF01698.11 KKK20036.1 - 3.9 6.2 8.4 0.48 9.2 2.0 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein CDC45 PF02724.9 KKK20036.1 - 7.4 4.4 15.5 0.14 10.2 5.6 1.7 2 0 0 2 2 2 0 CDC45-like protein SUI1 PF01253.17 KKK20037.1 - 2.3e-17 62.5 0.0 4e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Dabb PF07876.7 KKK20037.1 - 0.0072 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Chitin_synth_2 PF03142.10 KKK20038.1 - 2.8e-22 78.8 12.5 3.9e-22 78.3 0.6 2.9 2 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KKK20038.1 - 5.3e-16 58.9 6.3 5.3e-16 58.9 4.4 2.8 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK20038.1 - 2.7e-15 56.7 0.0 4.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KKK20038.1 - 0.013 15.2 0.1 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 TRAPPC10 PF12584.3 KKK20039.1 - 3.8e-36 123.7 0.0 8.1e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun PF07919.7 KKK20039.1 - 0.0046 15.3 0.0 0.21 9.8 0.0 2.4 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Ank PF00023.25 KKK20040.1 - 7.4e-13 47.6 2.3 1.5e-06 27.7 0.5 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KKK20040.1 - 6.3e-11 42.4 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK20040.1 - 2.2e-09 37.2 0.4 2.2e-07 30.8 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK20040.1 - 5.9e-08 33.0 0.4 1.1e-06 28.9 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK20040.1 - 8.5e-08 31.7 0.4 0.0013 18.7 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 KKK20040.1 - 4.2e-07 29.8 0.8 1.2e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 IPT/TIG domain Glyco_hydro_61 PF03443.9 KKK20041.1 - 6e-86 287.7 0.8 6e-86 287.7 0.6 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 La PF05383.12 KKK20042.1 - 1.3e-18 66.5 0.1 2e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 KKK20042.1 - 5.1e-08 32.7 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK20042.1 - 2.1e-07 30.4 0.1 9e-07 28.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK20042.1 - 0.00097 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.15 KKK20043.1 - 1.8e-137 458.8 5.9 1.8e-137 458.8 4.1 3.2 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KKK20043.1 - 8.9e-13 47.5 0.1 1.5e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 KKK20043.1 - 0.0046 16.7 7.6 1.2 8.9 0.0 4.5 3 2 0 3 3 3 2 Cell division protein FtsA V_ATPase_I PF01496.14 KKK20043.1 - 0.059 11.2 12.0 0.091 10.5 8.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FGGY_C PF02782.11 KKK20043.1 - 0.072 12.7 0.1 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Metal_resist PF13801.1 KKK20043.1 - 2.3 8.2 7.7 0.66 9.9 0.1 2.4 2 0 0 2 2 2 0 Heavy-metal resistance GCFC PF07842.7 KKK20044.1 - 4.5e-89 298.4 3.6 4.5e-89 298.4 2.5 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KKK20044.1 - 1.3e-13 50.4 1.5 2.4e-13 49.6 1.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KKK20044.1 - 2.2e-06 27.4 0.2 7.2e-06 25.7 0.1 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF3425 PF11905.3 KKK20044.1 - 0.0049 16.7 0.3 0.015 15.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF1162 PF06650.7 KKK20045.1 - 4.4e-91 304.9 0.0 1.2e-89 300.2 0.0 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KKK20045.1 - 6.2e-42 141.8 0.0 1.9e-41 140.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KKK20045.1 - 1.2e-06 28.6 0.3 6.5e-06 26.2 0.0 2.4 3 0 0 3 3 3 1 ATG C terminal domain MFS_1 PF07690.11 KKK20046.1 - 5e-21 74.8 36.9 2.3e-15 56.1 15.1 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.8 KKK20046.1 - 8.1e-05 20.9 15.7 0.0036 15.4 1.4 2.6 3 0 0 3 3 3 2 Transmembrane secretion effector DUF3429 PF11911.3 KKK20047.1 - 1.8e-40 138.1 11.0 2.5e-40 137.7 7.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Allene_ox_cyc PF06351.6 KKK20047.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Allene oxide cyclase F-box PF00646.28 KKK20048.1 - 0.03 13.9 2.4 0.033 13.8 0.0 2.2 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KKK20048.1 - 5.1 6.8 8.3 0.59 9.8 0.1 2.8 3 0 0 3 3 3 0 F-box-like Sod_Fe_C PF02777.13 KKK20049.1 - 8e-40 134.9 1.1 1.2e-39 134.4 0.3 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KKK20049.1 - 8.3e-29 99.6 3.3 1.5e-28 98.8 2.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 KKK20049.1 - 0.0038 16.2 1.2 1.1 8.4 0.0 3.3 4 0 0 4 4 4 2 Immunity protein 15 DAHP_synth_2 PF01474.11 KKK20054.1 - 1.9e-119 398.9 0.0 2.4e-116 388.7 0.0 2.0 1 1 0 1 1 1 1 Class-II DAHP synthetase family ABC1 PF03109.11 KKK20055.1 - 1.5e-21 76.5 0.2 1.2e-20 73.6 0.1 2.3 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 KKK20055.1 - 0.023 14.4 0.5 0.14 11.8 0.1 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Lactamase_B PF00753.22 KKK20056.1 - 4.3e-09 36.3 0.8 7.1e-08 32.3 0.6 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK20056.1 - 0.00045 19.8 0.1 0.00063 19.3 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.20 KKK20112.1 - 2.1e-54 184.3 0.0 3.3e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20112.1 - 2.2e-23 82.6 0.0 8.8e-23 80.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KKK20112.1 - 0.02 13.7 0.1 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UMP1 PF05348.6 KKK20112.1 - 0.026 14.5 0.1 0.061 13.2 0.1 1.6 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 TMA7 PF09072.5 KKK20114.1 - 1.6e-23 82.9 16.1 1.8e-23 82.7 11.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF2312 PF10073.4 KKK20114.1 - 0.13 11.6 1.2 0.28 10.5 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Condensation PF00668.15 KKK20115.1 - 4e-101 337.8 0.0 2.1e-35 122.0 0.0 3.3 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 KKK20115.1 - 1.7e-31 109.0 0.8 2.6e-31 108.4 0.5 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KKK20115.1 - 5.8e-29 100.1 0.0 2.6e-11 43.5 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site Transferase PF02458.10 KKK20115.1 - 0.00022 19.7 0.0 0.9 7.9 0.0 3.7 4 0 0 4 4 4 2 Transferase family AMP-binding_C PF13193.1 KKK20115.1 - 0.008 17.1 0.1 0.022 15.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain gpW PF02831.10 KKK20115.1 - 0.055 13.0 0.8 3.9 7.0 0.1 3.3 2 0 0 2 2 2 0 gpW AMP-binding PF00501.23 KKK20116.1 - 2e-185 616.1 0.0 1e-73 248.1 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KKK20116.1 - 4.7e-53 180.0 0.0 3.8e-32 111.3 0.0 2.4 2 0 0 2 2 2 2 Condensation domain AMP-binding_C PF13193.1 KKK20116.1 - 4.4e-16 59.5 0.7 6.9e-09 36.5 0.2 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 KKK20116.1 - 1.4e-15 57.2 1.2 8.8e-07 29.1 0.1 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding PF00501.23 KKK20117.1 - 1.4e-99 333.3 0.0 1.8e-99 332.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK20117.1 - 1.2e-11 45.3 0.0 2.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SSP160 PF06933.6 KKK20118.1 - 0.35 8.7 16.3 0.41 8.5 11.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pex14_N PF04695.8 KKK20118.1 - 2.4 8.2 8.6 2.6 8.1 5.2 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.6 KKK20118.1 - 3.8 5.2 13.5 4.7 4.9 9.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UvdE PF03851.9 KKK20119.1 - 1.7e-110 368.3 0.0 2.3e-110 367.9 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF2183 PF09949.4 KKK20119.1 - 4.2e-32 110.0 0.0 8.9e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 KKK20119.1 - 0.079 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF1489 PF07370.6 KKK20124.1 - 0.034 13.6 0.2 0.27 10.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1489) F-box PF00646.28 KKK20124.1 - 0.073 12.7 1.1 2.4 7.9 0.0 2.7 2 0 0 2 2 2 0 F-box domain BpuSI_N PF15516.1 KKK20124.1 - 0.084 12.5 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 BpuSI N-terminal domain Methyltransf_31 PF13847.1 KKK20141.1 - 6.1e-15 55.1 0.0 1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KKK20141.1 - 2.7e-11 43.1 0.0 4.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KKK20141.1 - 4.3e-11 43.3 0.0 1.2e-10 41.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK20141.1 - 1.1e-10 41.5 0.0 3.1e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK20141.1 - 2.6e-09 37.4 0.0 7.2e-09 36.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PRMT5 PF05185.11 KKK20141.1 - 1.3e-08 34.2 0.0 1.6e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.1 KKK20141.1 - 7e-07 29.5 0.0 2.7e-06 27.6 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 KKK20141.1 - 9.4e-07 28.3 0.1 3e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KKK20141.1 - 1.3e-06 28.1 0.0 4.1e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK20141.1 - 1.9e-06 28.2 0.0 3.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KKK20141.1 - 1.4e-05 24.0 0.0 2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 KKK20141.1 - 2.9e-05 23.2 0.0 4.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KKK20141.1 - 0.00027 20.9 0.0 0.00093 19.2 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KKK20141.1 - 0.00034 19.8 0.0 0.00053 19.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 KKK20141.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KKK20141.1 - 0.0038 16.7 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 KKK20141.1 - 0.0058 15.7 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 KKK20141.1 - 0.019 14.5 0.1 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 KKK20141.1 - 0.05 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.11 KKK20141.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.1 KKK20141.1 - 0.062 14.1 0.0 0.18 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KKK20141.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Rsm22 PF09243.5 KKK20141.1 - 0.083 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DOT1 PF08123.8 KKK20141.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 AAA PF00004.24 KKK20142.1 - 1.2e-40 138.7 0.0 2.4e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KKK20142.1 - 3.4e-05 23.0 0.1 0.00011 21.2 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KKK20142.1 - 0.00012 21.7 1.4 0.00031 20.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK20142.1 - 0.00036 20.5 0.3 0.017 15.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 KKK20142.1 - 0.00072 19.5 1.7 0.0097 15.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KKK20142.1 - 0.0028 16.6 0.0 0.0074 15.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 KKK20142.1 - 0.0033 17.5 1.7 0.031 14.4 0.1 2.7 2 1 0 2 2 1 1 AAA domain PhoH PF02562.11 KKK20142.1 - 0.0053 16.0 0.2 0.052 12.7 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KKK20142.1 - 0.01 15.0 0.1 0.032 13.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KKK20142.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KKK20142.1 - 0.012 15.3 0.3 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 KKK20142.1 - 0.022 13.8 1.0 0.1 11.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 KKK20142.1 - 0.023 14.0 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 KKK20142.1 - 0.026 14.4 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KKK20142.1 - 0.042 13.2 0.9 0.5 9.7 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KKK20142.1 - 0.048 13.2 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KKK20142.1 - 0.048 14.4 0.1 0.048 14.4 0.1 2.9 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KKK20142.1 - 0.46 10.0 4.5 0.84 9.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF496 PF04363.7 KKK20142.1 - 0.96 9.3 9.5 0.47 10.3 0.6 3.2 2 1 1 3 3 2 0 Protein of unknown function (DUF496) TauD PF02668.11 KKK20143.1 - 4.5e-41 141.2 0.9 5.9e-41 140.8 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KKK20143.1 - 0.00062 20.2 0.1 0.035 14.6 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 KKK20144.1 - 3.2e-71 239.5 0.0 4.4e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20144.1 - 1.2e-30 106.5 0.0 1.7e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KKK20144.1 - 1.4e-14 54.3 2.1 1.4e-14 54.3 1.5 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KKK20144.1 - 3.7e-09 35.9 0.0 6.9e-09 35.0 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KKK20144.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KKK20144.1 - 0.054 12.8 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KKK20144.1 - 0.07 12.7 0.1 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KKK20144.1 - 0.12 11.3 0.1 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 KKK20145.1 - 0.0075 15.9 0.2 0.022 14.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like DUF4027 PF13219.1 KKK20145.1 - 0.033 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) Hairy_orange PF07527.8 KKK20145.1 - 0.32 10.7 1.6 0.65 9.7 0.1 2.3 1 1 1 2 2 2 0 Hairy Orange Spt5_N PF11942.3 KKK20145.1 - 1.1 9.9 10.4 1.9 9.1 7.2 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 KKK20145.1 - 2.5 7.5 6.1 4.4 6.8 4.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KKK20145.1 - 9.9 5.7 6.3 17 4.9 4.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PGM_PMM_I PF02878.11 KKK20146.1 - 1.4e-16 60.2 0.1 1.9e-07 30.6 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KKK20146.1 - 3.2e-16 59.5 0.2 1.4e-15 57.4 0.1 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KKK20146.1 - 1.3e-10 41.1 0.9 4.4e-10 39.4 0.2 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KKK20146.1 - 0.03 14.3 0.1 0.11 12.5 0.1 2.0 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DEAD PF00270.24 KKK20147.1 - 8.6e-49 165.2 0.0 1.7e-48 164.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK20147.1 - 1.6e-25 88.7 0.0 4e-25 87.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK20147.1 - 0.0021 17.9 0.0 0.0059 16.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Per1 PF04080.8 KKK20148.1 - 4.4e-108 360.7 15.7 5.5e-108 360.4 10.8 1.1 1 0 0 1 1 1 1 Per1-like Lum_binding PF00677.12 KKK20149.1 - 6.7e-35 118.8 0.6 5.9e-20 70.9 0.1 2.2 2 0 0 2 2 2 2 Lumazine binding domain Brix PF04427.13 KKK20150.1 - 1.2e-58 197.9 0.3 1.8e-58 197.3 0.2 1.3 1 0 0 1 1 1 1 Brix domain Spore_coat_CotO PF14153.1 KKK20150.1 - 6.3 6.2 21.6 6.7 6.1 0.3 2.2 2 0 0 2 2 2 0 Spore coat protein CotO PHD PF00628.24 KKK20151.1 - 2.3e-09 36.8 9.0 3.8e-09 36.1 6.2 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KKK20151.1 - 0.0007 19.2 2.3 0.0014 18.3 1.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 KKK20151.1 - 0.0012 18.7 1.9 0.0019 18.0 1.3 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger Herpes_UL52 PF03121.10 KKK20151.1 - 0.11 12.2 2.2 0.21 11.3 1.5 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Prok-RING_1 PF14446.1 KKK20151.1 - 0.11 12.2 4.3 0.23 11.2 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KKK20151.1 - 0.7 9.2 11.1 0.16 11.2 4.5 2.3 2 1 0 2 2 2 0 PHD-finger CoA_transf_3 PF02515.12 KKK20152.1 - 3e-58 196.2 0.0 4.4e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III APH PF01636.18 KKK20159.1 - 0.0016 18.1 0.1 0.041 13.6 0.1 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Cu-oxidase_3 PF07732.10 KKK20160.1 - 1.9e-34 117.8 0.0 6.6e-34 116.1 0.0 2.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK20160.1 - 1.4e-29 102.3 4.0 7.2e-23 80.6 0.7 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK20160.1 - 5.6e-16 58.8 0.0 2.9e-15 56.5 0.0 2.2 1 1 0 1 1 1 1 Multicopper oxidase WD40 PF00400.27 KKK20161.1 - 8.8e-25 85.6 23.7 4.8e-08 32.5 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KKK20161.1 - 0.00014 21.6 0.0 0.0016 18.1 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF1014 PF06244.7 KKK20162.1 - 1.8e-24 86.3 6.5 3.9e-24 85.1 4.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF1510 PF07423.6 KKK20162.1 - 8 5.7 15.7 13 5.0 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CBFB_NFYA PF02045.10 KKK20165.1 - 1.2e-30 105.8 4.1 2.3e-30 104.8 2.9 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 KKK20165.1 - 0.085 11.7 0.4 0.17 10.8 0.1 1.5 1 1 0 1 1 1 0 Hus1-like protein MFS_1 PF07690.11 KKK20166.1 - 2.3e-43 148.2 43.8 2.3e-43 148.2 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20166.1 - 3.8e-06 25.7 28.5 9.8e-05 21.0 19.7 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter SNF2_N PF00176.18 KKK20167.1 - 7.8e-71 238.3 0.0 1.1e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KKK20167.1 - 3.5e-15 55.8 0.0 7.1e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 KKK20167.1 - 8.9e-11 41.4 7.7 2.4e-10 40.0 5.4 1.8 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 KKK20167.1 - 2.9e-09 36.6 0.1 1.1e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KKK20167.1 - 4.6e-09 36.1 10.2 8.7e-09 35.2 5.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK20167.1 - 4.1e-08 32.7 8.2 2e-07 30.5 4.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK20167.1 - 4.4e-08 32.6 8.3 4.4e-08 32.6 5.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KKK20167.1 - 1.8e-07 30.9 8.8 2.2e-07 30.6 5.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KKK20167.1 - 3.5e-07 29.6 7.1 4.6e-07 29.2 4.1 1.8 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KKK20167.1 - 1.7e-06 28.0 3.1 6e-06 26.2 2.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KKK20167.1 - 7.7e-06 25.5 6.0 1.9e-05 24.2 4.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.10 KKK20167.1 - 8e-06 25.7 0.1 4.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-Apc11 PF12861.2 KKK20167.1 - 0.00011 21.9 0.5 0.00025 20.8 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KKK20167.1 - 0.001 18.7 4.9 0.001 18.7 3.4 2.4 3 0 0 3 3 2 1 RING-type zinc-finger Pterin_bind PF00809.17 KKK20167.1 - 0.1 11.9 0.1 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Pterin binding enzyme zf-RING_4 PF14570.1 KKK20167.1 - 0.52 9.9 5.6 1.9 8.1 4.0 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1644 PF07800.7 KKK20167.1 - 1.3 8.8 6.6 8 6.2 0.2 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1644) GSH_synth_ATP PF03917.12 KKK20168.1 - 6.2e-89 298.1 0.0 8.1e-87 291.2 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KKK20168.1 - 1.6e-30 105.3 0.0 3.1e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 KKK20169.1 - 6.2e-42 143.4 0.0 3.5e-40 137.6 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK20169.1 - 1.1e-13 50.8 0.0 2.6e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK20169.1 - 0.00015 21.6 0.1 0.0024 17.7 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SAM_1 PF00536.25 KKK20169.1 - 0.015 15.4 0.1 0.044 13.9 0.1 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Epimerase PF01370.16 KKK20175.1 - 4.1e-45 154.0 0.0 5.5e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KKK20175.1 - 2.8e-26 91.2 0.1 5.2e-26 90.3 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KKK20175.1 - 3.3e-14 52.2 0.0 4.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KKK20175.1 - 8.1e-11 41.3 0.0 1.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KKK20175.1 - 4.9e-10 39.5 0.1 8.7e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KKK20175.1 - 5.6e-10 38.6 0.1 7.8e-09 34.8 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KKK20175.1 - 3.7e-06 27.0 0.0 5.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KKK20175.1 - 9.1e-06 25.4 0.1 2.1e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KKK20175.1 - 9.3e-05 21.4 0.0 0.00046 19.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Methyltransf_18 PF12847.2 KKK20175.1 - 0.0053 17.3 0.0 2 9.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain 3HCDH_N PF02737.13 KKK20175.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KKK20175.1 - 0.025 13.9 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cys_Met_Meta_PP PF01053.15 KKK20175.1 - 0.051 11.8 0.1 0.28 9.4 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme PAT1 PF09770.4 KKK20176.1 - 2.2e-290 965.5 12.5 2.5e-290 965.4 8.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 KKK20177.1 - 1.4e-137 458.1 8.6 1.7e-137 457.8 6.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.20 KKK20178.1 - 3.5e-41 139.4 1.1 4.7e-41 139.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UMP1 PF05348.6 KKK20179.1 - 5.6e-13 48.9 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.1 KKK20180.1 - 2.8e-12 46.5 0.0 4.7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KKK20180.1 - 0.0015 17.8 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KKK20180.1 - 0.0032 17.6 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain EXS PF03124.9 KKK20181.1 - 4e-95 318.7 31.4 5.1e-95 318.4 21.8 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KKK20181.1 - 1.6e-66 224.9 1.4 2.6e-66 224.2 1.0 1.4 1 0 0 1 1 1 1 SPX domain DUF3184 PF11380.3 KKK20182.1 - 1.7e-21 75.9 1.4 9.3e-12 43.7 0.0 4.0 1 1 1 3 3 3 3 Protein of unknown function (DUF3184) Abhydrolase_3 PF07859.8 KKK20183.1 - 5.8e-36 124.0 0.1 1.2e-24 87.0 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK20183.1 - 0.035 13.8 0.0 0.13 12.0 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family CLN3 PF02487.12 KKK20184.1 - 2.2e-100 336.2 16.2 5.1e-93 312.0 4.9 2.3 1 1 1 2 2 2 2 CLN3 protein MFS_1 PF07690.11 KKK20184.1 - 0.00056 18.7 20.7 0.0018 17.0 12.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily HMGL-like PF00682.14 KKK20185.1 - 9e-41 140.0 0.0 1.3e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Diphthamide_syn PF01866.12 KKK20186.1 - 7.6e-114 380.0 0.0 9e-114 379.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Bromodomain PF00439.20 KKK20187.1 - 2.3e-16 59.4 0.0 1.4e-15 56.9 0.0 2.2 2 0 0 2 2 2 1 Bromodomain ELYS PF13934.1 KKK20216.1 - 1.3e-77 260.6 0.5 1.5e-77 260.3 0.4 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 KKK20217.1 - 1.3e-80 269.7 0.0 2.3e-80 268.9 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KKK20217.1 - 3e-27 94.9 0.1 9.7e-27 93.3 0.0 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KKK20217.1 - 1.1e-13 51.8 6.4 6.7e-07 29.5 0.1 3.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KKK20217.1 - 3.6e-05 23.2 0.0 0.00011 21.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KKK20217.1 - 0.0021 17.2 20.0 0.15 11.2 0.3 4.2 2 1 2 4 4 4 4 Reovirus sigma C capsid protein ATG16 PF08614.6 KKK20217.1 - 0.0053 16.6 2.1 0.0053 16.6 1.5 7.8 3 2 6 9 9 9 1 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KKK20217.1 - 3.7 6.1 100.4 0.0037 15.9 6.4 6.3 2 2 2 5 5 5 0 Spc7 kinetochore protein AAA_13 PF13166.1 KKK20217.1 - 4.7 5.5 100.3 0.011 14.2 13.6 6.2 3 2 3 6 6 6 0 AAA domain Ribosomal_S10 PF00338.17 KKK20218.1 - 5.8e-27 93.3 0.3 6.9e-27 93.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1657 PF07870.6 KKK20219.1 - 0.059 13.0 0.2 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) CUE PF02845.11 KKK20220.1 - 3.5e-06 26.3 0.0 9.7e-06 24.9 0.0 1.8 1 0 0 1 1 1 1 CUE domain Abhydrolase_3 PF07859.8 KKK20236.1 - 3.1e-49 167.4 0.1 4.6e-49 166.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK20236.1 - 2.4e-07 29.8 1.6 5.2e-07 28.7 1.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KKK20236.1 - 8e-05 22.4 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK20236.1 - 0.049 12.8 0.2 4.3 6.4 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family adh_short PF00106.20 KKK20266.1 - 0.044 13.6 0.0 0.16 11.8 0.0 1.9 1 1 1 2 2 2 0 short chain dehydrogenase NAD_binding_6 PF08030.7 KKK20267.1 - 2.9e-20 72.7 0.0 5.4e-18 65.3 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KKK20267.1 - 3.5e-14 52.5 0.0 1.2e-13 50.8 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KKK20267.1 - 1.1e-13 51.3 2.5 1.1e-13 51.3 1.7 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DUF4405 PF14358.1 KKK20267.1 - 0.25 11.5 6.8 14 5.9 2.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) MSA-2c PF12238.3 KKK20268.1 - 0.17 11.4 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c GST_N_3 PF13417.1 KKK20269.1 - 4.5e-13 49.2 0.0 1.3e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK20269.1 - 1.9e-11 43.8 0.0 5.4e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK20269.1 - 1.2e-10 41.1 0.1 2.6e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK20269.1 - 2.1e-10 40.6 0.0 4.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK20269.1 - 1.1e-09 38.1 0.0 2.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK20269.1 - 1.8e-07 31.5 0.1 4.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BCS1_N PF08740.6 KKK20270.1 - 1.6e-22 80.0 0.4 2.2e-22 79.6 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KKK20270.1 - 9.6e-18 64.6 0.0 1.7e-16 60.5 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KKK20270.1 - 0.00096 18.5 0.0 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK20270.1 - 0.0024 18.6 0.0 0.0083 16.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK20270.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK20270.1 - 0.013 15.5 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 KKK20270.1 - 0.022 13.6 0.0 0.052 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.7 KKK20270.1 - 0.037 13.0 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KKK20270.1 - 0.044 12.4 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 KKK20270.1 - 0.05 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KKK20270.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KKK20270.1 - 0.057 12.0 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase AAA_24 PF13479.1 KKK20270.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK20270.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK20270.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.6 KKK20270.1 - 0.2 10.3 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain DUF3723 PF12520.3 KKK20271.1 - 9.1e-157 522.6 0.1 1.8e-154 514.9 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) APC10 PF03256.11 KKK20281.1 - 8e-40 136.5 0.0 1.5e-30 106.2 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) Nucleoplasmin PF03066.10 KKK20281.1 - 8.5 5.8 13.2 0.39 10.2 1.2 2.5 2 0 0 2 2 2 0 Nucleoplasmin PS_Dcarbxylase PF02666.10 KKK20282.1 - 7.2e-86 286.6 0.0 1.6e-85 285.4 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ubiquitin PF00240.18 KKK20283.1 - 1.1e-07 31.1 0.0 2.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Sugar_tr PF00083.19 KKK20284.1 - 1.9e-46 158.6 9.4 8.8e-35 120.1 7.6 1.9 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK20284.1 - 8.1e-05 21.4 14.2 0.00075 18.3 10.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Chitin_synth_2 PF03142.10 KKK20284.1 - 0.1 10.9 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 Chitin synthase Bax1-I PF01027.15 KKK20284.1 - 0.8 9.2 13.7 2.3 7.7 9.5 1.6 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 OPT PF03169.10 KKK20285.1 - 3.3e-31 108.4 6.4 3.8e-31 108.2 4.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SNARE PF05739.14 KKK20286.1 - 0.0054 16.3 0.4 0.0077 15.9 0.3 1.2 1 0 0 1 1 1 1 SNARE domain Rootletin PF15035.1 KKK20286.1 - 0.056 13.4 0.4 0.062 13.2 0.2 1.0 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Arrestin_C PF02752.17 KKK20287.1 - 1.9e-18 66.8 0.0 4.1e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KKK20287.1 - 1.2e-15 57.5 0.0 2.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KKK20287.1 - 0.0009 18.7 0.0 0.0029 17.1 0.0 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like APH PF01636.18 KKK20288.1 - 5.2e-24 85.2 0.0 7.1e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK20288.1 - 4.8e-07 29.5 0.0 7.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KKK20288.1 - 0.012 14.9 0.1 0.07 12.4 0.0 1.9 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 KKK20288.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Miro PF08477.8 KKK20289.1 - 1.5e-37 128.6 0.0 4.6e-18 65.8 0.0 3.7 4 0 0 4 4 3 2 Miro-like protein EF_assoc_2 PF08356.7 KKK20289.1 - 5.3e-34 115.8 0.0 9.8e-34 114.9 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 KKK20289.1 - 2.7e-31 106.6 0.1 5.3e-31 105.7 0.1 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 KKK20289.1 - 6.6e-25 87.3 0.0 1.5e-13 50.4 0.0 2.3 2 0 0 2 2 2 2 Ras family WD40 PF00400.27 KKK20289.1 - 7.1e-19 66.9 5.6 2.6e-05 23.9 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat MMR_HSR1 PF01926.18 KKK20289.1 - 2.5e-10 40.3 0.0 0.00045 20.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KKK20289.1 - 4.4e-05 23.5 1.3 0.3 11.0 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_1 PF00036.27 KKK20289.1 - 5.4e-05 22.2 1.4 0.032 13.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KKK20289.1 - 0.00016 21.7 0.3 0.035 14.2 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_22 PF13401.1 KKK20289.1 - 0.00042 20.4 0.3 2.3 8.3 0.0 3.0 2 1 1 3 3 3 2 AAA domain Dynamin_N PF00350.18 KKK20289.1 - 0.00049 19.9 0.8 1.1 9.0 0.1 3.0 2 1 1 3 3 2 2 Dynamin family EF-hand_8 PF13833.1 KKK20289.1 - 0.00061 19.3 0.9 0.064 12.8 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair IKI3 PF04762.7 KKK20289.1 - 0.00069 17.5 0.0 0.003 15.4 0.0 1.7 1 1 1 2 2 2 1 IKI3 family AAA_28 PF13521.1 KKK20289.1 - 0.00081 19.3 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_6 PF13405.1 KKK20289.1 - 0.0013 18.4 1.1 0.14 12.1 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain AAA_29 PF13555.1 KKK20289.1 - 0.0031 16.9 0.3 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 KKK20289.1 - 0.0037 16.7 0.0 0.33 10.3 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain eIF2A PF08662.6 KKK20289.1 - 0.0048 16.6 0.1 0.069 12.8 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A FtsK_SpoIIIE PF01580.13 KKK20289.1 - 0.0058 16.1 0.1 1 8.7 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 KKK20289.1 - 0.0076 15.9 0.1 0.51 10.0 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KKK20289.1 - 0.014 15.5 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 KKK20289.1 - 0.015 15.6 0.0 5.2 7.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 KKK20289.1 - 0.019 14.5 0.1 0.17 11.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KKK20289.1 - 0.021 14.3 0.3 0.21 11.0 0.0 2.5 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 KKK20289.1 - 0.023 13.8 0.2 3.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KKK20289.1 - 0.034 13.2 0.0 7.2 5.6 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin GTP_EFTU PF00009.22 KKK20289.1 - 0.041 13.3 0.1 2 7.8 0.0 2.6 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 KKK20289.1 - 0.047 13.0 0.0 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KKK20289.1 - 0.053 13.1 0.2 12 5.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 KKK20289.1 - 0.057 13.2 0.0 11 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Cytochrom_D1 PF02239.11 KKK20289.1 - 0.087 11.1 0.0 0.19 9.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Arch_ATPase PF01637.13 KKK20289.1 - 0.091 12.4 0.2 4.3 6.9 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase IIGP PF05049.8 KKK20289.1 - 0.1 11.3 0.3 0.7 8.6 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Septin PF00735.13 KKK20289.1 - 0.14 11.1 0.0 2.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Septin DUF815 PF05673.8 KKK20289.1 - 0.17 10.7 0.1 3.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 KKK20289.1 - 0.19 12.0 0.0 17 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain EF-hand_5 PF13202.1 KKK20289.1 - 0.31 10.4 3.3 1.3 8.5 0.2 2.5 2 0 0 2 2 2 0 EF hand cobW PF02492.14 KKK20289.1 - 0.4 10.1 4.2 0.71 9.2 0.1 3.2 4 1 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 KKK20289.1 - 0.59 9.6 1.9 39 3.6 0.0 3.3 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein EMP24_GP25L PF01105.19 KKK20290.1 - 2.5e-43 147.9 0.0 3e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 KKK20290.1 - 0.052 11.7 0.3 0.068 11.3 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Zds_C PF08632.5 KKK20291.1 - 2.8e-31 106.6 1.0 4.8e-31 105.9 0.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF500 PF04366.7 KKK20292.1 - 3.1e-44 149.4 0.2 6.3e-44 148.4 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KKK20292.1 - 1.5e-13 49.9 0.3 4.6e-13 48.3 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KKK20292.1 - 6.1e-09 35.2 1.0 1e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KKK20292.1 - 1.4e-08 34.1 0.1 3.7e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain Prenyltransf PF01255.14 KKK20293.1 - 3.1e-81 271.7 0.0 6.1e-81 270.7 0.0 1.4 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Saccharop_dh PF03435.13 KKK20294.1 - 2.6e-119 398.6 0.0 3.3e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KKK20294.1 - 7.1e-10 39.1 0.2 1.2e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KKK20294.1 - 8.7e-08 32.3 0.3 1.7e-06 28.1 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KKK20294.1 - 0.00058 19.1 0.2 0.00086 18.6 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KKK20294.1 - 0.0021 16.8 0.1 0.0042 15.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.1 KKK20294.1 - 0.015 15.5 0.1 0.06 13.6 0.2 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding COesterase PF00135.23 KKK20312.1 - 9.3e-08 31.2 0.2 1e-07 31.1 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Pkinase PF00069.20 KKK20313.1 - 8.6e-62 208.6 0.0 1.1e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20313.1 - 1.4e-36 125.9 0.0 1.9e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK20313.1 - 2e-09 36.8 0.0 2.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KKK20313.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KKK20313.1 - 0.22 10.5 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PLRV_ORF5 PF01690.12 KKK20313.1 - 6.6 5.7 12.9 11 5.0 9.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Sec39 PF08314.6 KKK20314.1 - 5.1e-251 834.6 0.1 5.8e-251 834.4 0.1 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF515 PF04415.7 KKK20315.1 - 2.8 6.0 6.2 4.7 5.3 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Ndufs5 PF10200.4 KKK20316.1 - 0.00061 19.7 0.1 0.00075 19.4 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 KKK20316.1 - 0.0031 17.6 1.4 0.0064 16.5 1.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 KKK20316.1 - 0.016 15.1 0.2 0.029 14.4 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 KKK20316.1 - 0.19 11.5 2.5 0.36 10.7 1.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) LysM PF01476.15 KKK20317.1 - 3.3e-22 78.0 0.0 1.2e-05 25.1 0.0 4.4 4 0 0 4 4 4 4 LysM domain Phage_tail_X PF05489.7 KKK20317.1 - 0.089 12.2 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Phage Tail Protein X Exo_endo_phos PF03372.18 KKK20318.1 - 3.6e-14 53.3 0.2 7.2e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KKK20318.1 - 0.17 11.5 1.9 1.4 8.5 0.1 3.0 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase FSH1 PF03959.8 KKK20319.1 - 3.3e-25 88.7 0.0 3.8e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KKK20319.1 - 0.00042 19.8 0.0 0.0012 18.2 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KKK20319.1 - 0.021 14.6 0.0 0.053 13.2 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family MazG PF03819.12 KKK20319.1 - 0.031 14.2 0.2 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain TSC22 PF01166.13 KKK20319.1 - 0.085 12.8 0.1 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family tRNA-synt_1c PF00749.16 KKK20320.1 - 1.3e-90 303.2 0.0 1.9e-90 302.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KKK20320.1 - 2.4e-31 108.7 0.0 7.5e-31 107.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain NAD_binding_10 PF13460.1 KKK20321.1 - 2.8e-06 27.4 0.0 3.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KKK20321.1 - 0.0085 15.0 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KKK20321.1 - 0.039 14.2 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CbiN PF02553.10 KKK20321.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Cobalt transport protein component CbiN Epimerase PF01370.16 KKK20321.1 - 0.065 12.6 0.0 0.08 12.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 KKK20322.1 - 4.7e-08 32.8 7.5 8.7e-08 31.9 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1488 PF07369.6 KKK20322.1 - 0.053 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) Mac PF12464.3 KKK20323.1 - 2.9e-21 75.2 0.2 4.6e-21 74.5 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KKK20323.1 - 3.6e-13 48.3 12.7 1.1e-11 43.6 3.1 3.5 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK20323.1 - 1.1e-12 47.2 9.8 4.8e-11 42.0 3.6 3.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Abhydrolase_6 PF12697.2 KKK20325.1 - 8.6e-14 51.9 0.5 2.2e-13 50.6 0.4 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_54 PF04666.8 KKK20325.1 - 2.3e-12 46.2 0.0 2.8e-10 39.4 0.1 3.0 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Abhydrolase_5 PF12695.2 KKK20325.1 - 6e-10 39.0 0.0 1.4e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KKK20325.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 KKK20325.1 - 0.0072 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF1749 PF08538.5 KKK20325.1 - 0.025 13.4 0.0 0.054 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 KKK20325.1 - 0.076 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KKK20325.1 - 0.094 12.1 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 KKK20325.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) NAD_binding_4 PF07993.7 KKK20326.1 - 0.00041 19.3 0.0 0.031 13.2 0.0 2.6 3 0 0 3 3 3 1 Male sterility protein DapB_N PF01113.15 KKK20326.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KKK20326.1 - 0.02 15.1 0.0 0.048 13.9 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KKK20326.1 - 0.021 13.7 0.1 0.096 11.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 KKK20326.1 - 0.028 13.8 0.1 0.4 10.0 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 KKK20327.1 - 3.2e-45 154.5 0.0 1.7e-44 152.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Fungal_trans_2 PF11951.3 KKK20328.1 - 5.2e-07 28.5 0.1 8.9e-07 27.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20328.1 - 2e-06 27.5 9.0 4.5e-06 26.4 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIT PF04212.13 KKK20328.1 - 0.16 11.8 0.0 9.7 6.1 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain MFS_1 PF07690.11 KKK20329.1 - 8.1e-47 159.6 28.0 8.1e-47 159.6 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20329.1 - 1.1e-10 40.7 13.5 1.1e-10 40.7 9.3 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 KKK20329.1 - 0.0016 16.5 9.4 0.71 7.8 0.0 3.5 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family G_glu_transpept PF01019.16 KKK20330.1 - 2e-146 488.4 0.0 2.3e-146 488.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase FYVE_2 PF02318.11 KKK20331.1 - 0.35 10.7 9.7 0.13 12.2 1.5 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C2H2_4 PF13894.1 KKK20332.1 - 5.1e-07 29.5 15.3 3e-05 24.0 2.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK20332.1 - 1.4e-06 28.2 10.8 0.0012 19.0 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-CGNR PF11706.3 KKK20332.1 - 0.89 9.1 4.6 0.42 10.1 0.7 2.1 2 0 0 2 2 2 0 CGNR zinc finger CHORD PF04968.7 KKK20332.1 - 1.3 9.3 4.8 11 6.3 0.5 2.3 1 1 1 2 2 2 0 CHORD zf-H2C2_2 PF13465.1 KKK20332.1 - 3.3 8.1 15.7 1.1 9.6 2.4 3.3 3 0 0 3 3 3 0 Zinc-finger double domain CactinC_cactus PF09732.4 KKK20333.1 - 9.1e-45 151.2 2.2 1.9e-44 150.2 1.5 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 KKK20333.1 - 7.7e-25 87.2 0.9 1.3e-24 86.5 0.6 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin Fork_head PF00250.13 KKK20333.1 - 2.5e-16 59.5 0.1 5.6e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 Fork head domain DUF1087 PF06465.8 KKK20333.1 - 0.028 14.3 1.0 0.31 10.9 0.1 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) HEAT_2 PF13646.1 KKK20334.1 - 2.2e-08 34.2 7.7 3.2e-05 24.1 1.0 5.9 5 2 2 7 7 7 2 HEAT repeats RIX1 PF08167.7 KKK20334.1 - 6.5e-05 22.6 0.5 0.46 10.1 0.0 4.8 6 0 0 6 6 6 2 rRNA processing/ribosome biogenesis HEAT PF02985.17 KKK20334.1 - 0.00011 21.9 13.4 0.028 14.4 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KKK20334.1 - 0.00018 21.8 6.9 0.0098 16.3 0.1 4.5 4 0 0 4 4 4 1 HEAT-like repeat Nipped-B_C PF12830.2 KKK20334.1 - 0.022 14.3 1.0 1.5 8.4 0.0 3.8 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KKK20334.1 - 0.037 13.9 1.3 4.5 7.3 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion TFIIA PF03153.8 KKK20334.1 - 1.6 8.5 25.8 3.6 7.3 17.9 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.11 KKK20335.1 - 1.9e-39 135.3 37.7 1.9e-39 135.3 26.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-RING_2 PF13639.1 KKK20336.1 - 6.3e-10 38.7 0.7 6.3e-10 38.7 0.5 3.3 3 0 0 3 3 3 1 Ring finger domain PHD PF00628.24 KKK20336.1 - 6.5e-10 38.5 13.2 1.7e-09 37.2 4.1 2.5 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_2 PF13923.1 KKK20336.1 - 1.2e-06 28.4 0.8 1.2e-06 28.4 0.6 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK20336.1 - 1.7e-06 27.5 0.6 1.7e-06 27.5 0.4 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK20336.1 - 2.4e-06 27.1 0.3 2.4e-06 27.1 0.2 3.2 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK20336.1 - 3.1e-06 26.7 0.1 3.1e-06 26.7 0.1 2.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 KKK20336.1 - 9.7e-06 24.8 1.8 2.1e-05 23.7 1.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.2 KKK20336.1 - 3.8e-05 23.7 3.7 3.8e-05 23.7 2.6 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 KKK20336.1 - 0.0012 18.3 0.5 0.0012 18.3 0.4 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KKK20336.1 - 0.0035 17.1 0.0 0.0035 17.1 0.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KKK20336.1 - 0.028 14.1 2.2 0.095 12.4 0.5 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 KKK20336.1 - 0.07 12.7 0.1 0.07 12.7 0.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 KKK20336.1 - 0.096 11.8 0.0 0.096 11.8 0.0 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger DUF2051 PF09738.4 KKK20336.1 - 0.27 10.5 1.8 0.48 9.6 1.2 1.3 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DZR PF12773.2 KKK20336.1 - 0.48 10.2 4.9 11 5.9 1.8 2.7 2 1 1 3 3 3 0 Double zinc ribbon zf-C2HC_2 PF13913.1 KKK20336.1 - 0.83 9.3 4.6 0.65 9.7 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RINGv PF12906.2 KKK20336.1 - 8.9 6.4 10.7 0.54 10.3 1.1 2.5 2 0 0 2 2 2 0 RING-variant domain zf-RING-like PF08746.6 KKK20336.1 - 9.1 6.3 12.9 11 6.0 0.6 2.4 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.1 KKK20336.1 - 9.7 6.0 8.7 1.3 8.8 0.8 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Alg6_Alg8 PF03155.10 KKK20337.1 - 2.5e-139 465.1 32.1 3e-139 464.8 22.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 KKK20338.1 - 8.2e-27 93.8 0.0 1.3e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family IncA PF04156.9 KKK20338.1 - 0.029 13.9 7.2 0.054 13.0 5.0 1.4 1 0 0 1 1 1 0 IncA protein EMP24_GP25L PF01105.19 KKK20338.1 - 0.061 13.0 2.3 0.13 11.9 1.6 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FAM196 PF15265.1 KKK20338.1 - 0.065 12.4 5.4 0.083 12.1 3.7 1.1 1 0 0 1 1 1 0 FAM196 family FolB PF02152.13 KKK20338.1 - 0.09 12.9 0.2 5.3 7.2 0.0 2.3 1 1 1 2 2 2 0 Dihydroneopterin aldolase FUSC PF04632.7 KKK20338.1 - 0.19 10.1 2.0 0.25 9.7 1.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4349 PF14257.1 KKK20338.1 - 0.7 9.0 7.8 12 5.0 5.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Seryl_tRNA_N PF02403.17 KKK20338.1 - 2.1 8.3 6.8 4.1 7.4 4.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SNF5 PF04855.7 KKK20339.1 - 1.5e-80 270.1 0.5 2.4e-80 269.5 0.4 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF4648 PF15505.1 KKK20339.1 - 0.12 12.5 4.8 0.037 14.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) Exo_endo_phos PF03372.18 KKK20340.1 - 6.1e-06 26.3 0.8 2.8e-05 24.1 0.5 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M24 PF00557.19 KKK20341.1 - 4.8e-14 52.4 0.0 6.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.24 KKK20342.1 - 8.2e-20 70.2 19.0 2.1e-12 46.5 4.8 2.6 2 1 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.1 KKK20342.1 - 0.0021 18.1 4.7 0.69 10.0 0.2 2.4 2 0 0 2 2 2 2 PHD-like zinc-binding domain C1_1 PF00130.17 KKK20342.1 - 0.024 14.3 11.9 0.073 12.8 1.5 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 KKK20342.1 - 0.064 12.5 11.1 0.44 9.8 1.7 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 KKK20342.1 - 0.29 10.4 19.2 0.1 11.9 1.2 3.6 4 0 0 4 4 4 0 PHD-finger Prok-RING_1 PF14446.1 KKK20342.1 - 0.76 9.5 12.8 0.13 12.0 2.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.1 KKK20342.1 - 3.2 7.7 7.0 17 5.4 0.4 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain Ribosomal_L37ae PF01780.14 KKK20343.1 - 8e-41 137.8 10.1 9.1e-41 137.6 7.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 KKK20343.1 - 0.0015 17.8 3.6 0.1 12.0 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KKK20343.1 - 0.0016 18.1 2.9 0.0024 17.6 2.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Sgf11 PF08209.6 KKK20343.1 - 0.15 11.4 0.6 0.96 8.8 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-BED PF02892.10 KKK20343.1 - 0.16 11.7 4.6 1.9 8.2 0.2 2.5 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 KKK20343.1 - 0.22 11.5 1.8 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain NOB1_Zn_bind PF08772.6 KKK20343.1 - 0.39 10.5 4.2 2.1 8.2 2.5 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like CarbpepA_inh PF02977.10 KKK20343.1 - 0.48 10.0 4.5 5 6.7 3.1 2.1 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 KKK20343.1 - 0.85 10.0 3.4 8.2 6.9 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK20343.1 - 2.6 8.5 6.1 4.3 7.8 0.5 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Saccharop_dh PF03435.13 KKK20344.1 - 5.4e-20 71.7 0.0 7.3e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Abhydrolase_6 PF12697.2 KKK20345.1 - 2.2e-32 112.8 0.0 2.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK20345.1 - 3.3e-18 66.1 0.1 1.4e-17 64.0 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK20345.1 - 3.5e-13 49.5 0.0 1.5e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK20345.1 - 0.0018 18.1 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KKK20345.1 - 0.025 13.0 0.0 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Pinin_SDK_memA PF04696.8 KKK20346.1 - 7.3e-29 100.0 21.6 1.4e-28 99.1 9.0 2.3 2 0 0 2 2 2 2 pinin/SDK/memA/ protein conserved region Apolipoprotein PF01442.13 KKK20364.1 - 0.0082 15.6 2.4 0.013 14.9 1.7 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.13 KKK20364.1 - 0.0083 15.9 0.9 0.018 14.8 0.6 1.5 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) DUF883 PF05957.8 KKK20364.1 - 0.11 12.8 0.3 0.31 11.4 0.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF1762 PF08574.5 KKK20365.1 - 7.8e-23 80.6 7.3 7.8e-23 80.6 5.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1762) RRM_1 PF00076.17 KKK20366.1 - 9.4e-37 124.4 0.0 8.7e-12 44.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK20366.1 - 1.7e-36 124.0 0.1 2.3e-09 37.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK20366.1 - 6.3e-17 61.1 0.1 0.0016 18.2 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 KKK20366.1 - 5.6e-14 51.4 7.2 5.6e-14 51.4 5.0 2.6 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 KKK20366.1 - 0.00012 21.8 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 KKK20366.1 - 0.071 13.0 0.0 1.8 8.6 0.0 3.0 3 1 0 3 3 3 0 RNA binding domain NID PF07292.8 KKK20366.1 - 0.13 12.3 0.0 0.44 10.6 0.0 2.0 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) PB1 PF00564.19 KKK20385.1 - 6.5e-09 35.3 0.1 1.2e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 PB1 domain PH_10 PF15411.1 KKK20385.1 - 1.3e-06 28.5 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Med13_C PF06333.7 KKK20386.1 - 1.4 7.3 5.9 1.9 6.9 4.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal ECM11 PF15463.1 KKK20386.1 - 2 8.6 9.6 1.4 9.1 5.2 1.8 1 1 0 1 1 1 0 Extracellular mutant protein 11 MFS_1 PF07690.11 KKK20387.1 - 2.8e-30 105.2 41.5 4.8e-17 61.7 6.0 3.0 2 2 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20387.1 - 4e-06 25.6 5.9 4e-06 25.6 4.1 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter Phasin PF05597.6 KKK20388.1 - 0.061 13.0 0.4 0.14 11.8 0.3 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Pyridoxal_deC PF00282.14 KKK20389.1 - 6.7e-71 238.6 0.0 8.6e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Glyco_hydro_71 PF03659.9 KKK20390.1 - 2.9e-158 526.4 6.4 2.9e-158 526.4 4.4 1.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KKK20390.1 - 0.0089 15.7 1.3 0.38 10.4 0.3 3.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4434) WD40 PF00400.27 KKK20391.1 - 6.9e-14 51.1 3.3 0.097 12.5 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Lactonase PF10282.4 KKK20391.1 - 0.058 12.4 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Cyclin_N PF00134.18 KKK20392.1 - 1.1e-34 118.7 0.1 1.1e-34 118.7 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KKK20392.1 - 5.4e-14 52.1 0.1 1.1e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain UvrD_C PF13361.1 KKK20394.1 - 3.9e-76 256.7 0.0 1.9e-74 251.2 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KKK20394.1 - 6.5e-55 186.6 0.2 6.1e-35 121.0 0.2 2.5 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KKK20394.1 - 4.9e-14 52.3 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KKK20394.1 - 1.1e-12 47.5 0.3 4.1e-11 42.4 0.0 3.1 2 1 1 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KKK20394.1 - 5.5e-06 26.0 0.1 0.00012 21.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KKK20394.1 - 0.00012 21.5 0.0 0.0048 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KKK20394.1 - 0.0021 17.6 0.1 0.0072 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KKK20394.1 - 0.065 13.3 0.8 7.4 6.7 0.6 2.6 1 1 0 1 1 1 0 AAA domain Cyt-b5 PF00173.23 KKK20395.1 - 1.5e-14 53.5 0.0 2.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zip PF02535.17 KKK20396.1 - 1.7e-58 198.1 4.9 1.9e-58 197.9 3.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter MRI PF15325.1 KKK20397.1 - 0.33 11.9 3.1 0.59 11.1 2.0 1.5 1 1 0 1 1 1 0 Modulator of retrovirus infection Rpr2 PF04032.11 KKK20414.1 - 6e-28 96.5 0.1 1.2e-27 95.5 0.0 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 KKK20414.1 - 0.2 11.4 5.1 1.4 8.8 3.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon Baculo_PEP_C PF04513.7 KKK20415.1 - 0.037 13.8 2.5 1.3 8.8 0.9 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KKK20415.1 - 0.055 13.7 2.2 2.5 8.4 1.5 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nbl1_Borealin_N PF10444.4 KKK20415.1 - 0.078 12.3 0.9 0.078 12.3 0.6 2.3 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal Glyco_hydro_3_C PF01915.17 KKK20415.1 - 0.088 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain NAP PF00956.13 KKK20415.1 - 0.15 11.1 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Adeno_PIX PF03955.9 KKK20415.1 - 0.16 12.5 1.2 15 6.1 0.3 2.2 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Fzo_mitofusin PF04799.8 KKK20415.1 - 0.19 11.1 1.2 0.74 9.1 0.8 1.8 1 1 0 1 1 1 0 fzo-like conserved region ING PF12998.2 KKK20415.1 - 0.27 11.5 3.5 4.3 7.6 0.0 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Syntaxin PF00804.20 KKK20415.1 - 0.31 11.2 6.1 0.25 11.5 0.6 2.4 2 1 1 3 3 2 0 Syntaxin HSCB_C PF07743.8 KKK20415.1 - 0.33 11.4 2.9 2.4 8.6 0.5 2.3 1 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain CorA PF01544.13 KKK20415.1 - 0.49 9.3 5.5 0.97 8.4 2.1 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein IncA PF04156.9 KKK20415.1 - 0.8 9.2 6.1 1.1 8.8 4.2 1.4 1 1 0 1 1 1 0 IncA protein Uds1 PF15456.1 KKK20415.1 - 0.9 9.5 4.9 1.1 9.2 1.9 2.1 2 1 0 2 2 2 0 Up-regulated During Septation GreA_GreB_N PF03449.10 KKK20415.1 - 1.3 9.1 4.8 1.9 8.5 0.3 2.9 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal Matrilin_ccoil PF10393.4 KKK20415.1 - 1.6 8.1 5.8 4.8 6.6 0.4 3.0 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin ORF11CD3 PF10549.4 KKK20415.1 - 1.6 8.5 10.0 0.54 10.0 0.5 3.3 3 0 0 3 3 3 0 ORF11CD3 domain DUF4164 PF13747.1 KKK20415.1 - 9.6 6.4 8.5 4.9 7.3 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DEAD PF00270.24 KKK20416.1 - 8.1e-36 123.0 0.0 1.4e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK20416.1 - 5.6e-24 83.7 0.0 4.3e-23 80.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK20416.1 - 3.3e-06 27.0 0.0 9.3e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KKK20416.1 - 0.01 14.9 0.0 0.054 12.5 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit SMC_N PF02463.14 KKK20419.1 - 3.3e-60 203.0 0.0 5.7e-59 199.0 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KKK20419.1 - 9e-32 109.5 0.0 4.1e-31 107.4 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KKK20419.1 - 3e-12 47.1 1.3 5.5e-08 33.1 0.1 3.6 5 1 1 6 6 6 2 AAA domain AAA_29 PF13555.1 KKK20419.1 - 1.4e-08 34.1 0.0 2.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 KKK20419.1 - 2.2e-05 24.1 7.4 2.2e-05 24.1 5.1 7.2 3 2 4 7 7 7 3 IncA protein AAA_23 PF13476.1 KKK20419.1 - 7.8e-05 23.0 104.8 0.095 13.0 0.3 6.5 3 2 1 4 4 4 1 AAA domain SbcCD_C PF13558.1 KKK20419.1 - 0.0013 18.6 0.1 0.013 15.3 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MAD PF05557.8 KKK20419.1 - 0.0014 16.8 30.6 0.0014 16.8 21.2 4.7 3 2 1 4 4 4 1 Mitotic checkpoint protein AAA_22 PF13401.1 KKK20419.1 - 0.094 12.8 4.9 6.8 6.8 0.0 5.0 4 1 0 5 5 5 0 AAA domain E3_binding PF02817.12 KKK20420.1 - 1.4e-06 27.8 0.2 2.6e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 e3 binding domain FtsK_SpoIIIE PF01580.13 KKK20421.1 - 0.0017 17.8 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family B12-binding PF02310.14 KKK20421.1 - 0.003 17.4 0.1 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain GalP_UDP_transf PF01087.17 KKK20422.1 - 6.9e-68 228.3 0.1 4e-66 222.5 0.0 2.3 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KKK20422.1 - 7.8e-55 184.9 0.5 1.6e-54 183.9 0.2 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain Erg28 PF03694.8 KKK20423.1 - 1.7e-34 118.1 0.2 2.1e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein NAD_binding_2 PF03446.10 KKK20424.1 - 1.5e-11 44.3 0.2 7.4e-10 38.9 0.1 2.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KKK20424.1 - 3.8e-08 33.4 0.0 1.3e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase UDPGT PF00201.13 KKK20424.1 - 5.1e-08 31.9 0.0 9e-08 31.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Shikimate_DH PF01488.15 KKK20424.1 - 0.071 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_tran_28_C PF04101.11 KKK20424.1 - 0.08 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PRK PF00485.13 KKK20424.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family F-box-like PF12937.2 KKK20425.1 - 5.2e-06 26.0 0.4 1.2e-05 24.9 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK20425.1 - 0.0013 18.3 0.5 0.0028 17.2 0.3 1.5 1 0 0 1 1 1 1 F-box domain adh_short PF00106.20 KKK20426.1 - 7e-21 74.8 0.0 1.2e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK20426.1 - 3.2e-13 50.0 0.0 4.4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK20426.1 - 0.00014 21.6 0.0 0.00025 20.7 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK20426.1 - 0.0058 16.6 0.2 0.011 15.8 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KKK20426.1 - 0.027 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KKK20426.1 - 0.14 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.19 KKK20427.1 - 2.7e-97 326.1 15.1 3.2e-97 325.9 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK20427.1 - 4.1e-19 68.5 20.9 4.9e-19 68.2 14.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.4 KKK20427.1 - 0.02 14.8 1.4 0.02 14.8 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) AcetylCoA_hyd_C PF13336.1 KKK20428.1 - 2.6e-05 23.9 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF2249 PF10006.4 KKK20428.1 - 0.025 14.1 0.7 0.93 9.1 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) HD PF01966.17 KKK20429.1 - 2.4e-05 24.3 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 KKK20429.1 - 0.0046 16.2 0.1 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 HDOD domain Peptidase_M35 PF02102.10 KKK20430.1 - 2.6e-164 546.1 13.0 3.4e-164 545.7 9.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KKK20430.1 - 1.6e-07 31.9 1.6 1.9e-07 31.6 0.5 1.6 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 KKK20430.1 - 0.0036 16.7 1.4 0.0067 15.8 1.0 1.5 1 1 0 1 1 1 1 Putative peptidase family Tmemb_14 PF03647.8 KKK20431.1 - 1.7e-12 47.5 4.3 2.2e-12 47.1 3.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2339 PF10101.4 KKK20431.1 - 0.0013 17.0 1.9 0.0015 16.9 1.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF2530 PF10745.4 KKK20431.1 - 0.012 15.5 1.5 0.19 11.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) PEP_mutase PF13714.1 KKK20432.1 - 2e-36 125.4 0.2 2.2e-36 125.2 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KKK20432.1 - 7e-19 67.4 0.1 8e-19 67.2 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Glyco_hydro_17 PF00332.13 KKK20433.1 - 0.00029 19.9 0.7 0.00054 19.1 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 HTH_6 PF01418.12 KKK20433.1 - 0.082 12.6 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Acetyltransf_7 PF13508.1 KKK20434.1 - 1.7e-06 28.0 0.1 2.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK20434.1 - 1.7e-06 27.9 0.2 2.8e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK20434.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK20434.1 - 3.7e-05 23.8 0.1 0.00014 21.9 0.1 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK20434.1 - 0.0051 16.6 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SCA7 PF08313.7 KKK20457.1 - 4.6e-34 115.8 0.8 1.5e-33 114.1 0.6 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain DUF3505 PF12013.3 KKK20457.1 - 0.15 12.3 0.3 0.15 12.3 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) BTV_NS2 PF04514.7 KKK20457.1 - 0.6 8.9 11.0 1.3 7.7 7.6 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MIP-T3 PF10243.4 KKK20457.1 - 2.8 6.3 30.6 0.11 10.9 17.3 1.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 U79_P34 PF03064.11 KKK20457.1 - 6.4 6.2 18.3 16 4.9 12.7 1.7 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ketoacyl-synt_C PF02801.17 KKK20458.1 - 7.2e-33 112.9 1.8 9.5e-33 112.5 1.2 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_C PF02803.13 KKK20458.1 - 0.0065 15.8 0.5 0.0098 15.3 0.3 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain mRNA_cap_enzyme PF01331.14 KKK20459.1 - 1e-50 172.1 0.3 1.3e-50 171.7 0.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KKK20459.1 - 1.3e-21 76.9 0.0 2.7e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KKK20459.1 - 1.4e-08 34.3 0.3 2.7e-07 30.1 0.2 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain ECH_C PF13766.1 KKK20460.1 - 4.2e-40 136.5 0.2 9.3e-40 135.4 0.1 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KKK20460.1 - 1.7e-24 86.3 0.0 4.6e-24 84.8 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family PBP PF01161.15 KKK20461.1 - 2.9e-11 43.4 0.0 4.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.17 KKK20462.1 - 2.7e-44 150.8 0.0 3.3e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family BDV_P24 PF06595.6 KKK20462.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Borna disease virus P24 protein FA_hydroxylase PF04116.8 KKK20463.1 - 2.7e-13 50.2 18.3 2.7e-13 50.2 12.7 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Colicin_V PF02674.11 KKK20463.1 - 1.3 8.8 7.0 0.42 10.4 0.3 2.6 3 0 0 3 3 3 0 Colicin V production protein OGG_N PF07934.7 KKK20464.1 - 5.6e-37 126.2 0.2 1.4e-36 125.0 0.0 1.8 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KKK20464.1 - 1.1e-12 48.1 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PIG-S PF10510.4 KKK20464.1 - 0.61 8.6 5.4 0.78 8.3 3.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein RR_TM4-6 PF06459.7 KKK20464.1 - 4.6 7.0 11.5 6.5 6.5 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Myc_N PF01056.13 KKK20464.1 - 4.7 6.2 11.2 8.2 5.4 7.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Pyr_redox_3 PF13738.1 KKK20465.1 - 4.4e-27 95.4 0.0 2.8e-24 86.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK20465.1 - 1.3e-13 50.0 0.0 1.2e-12 46.8 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK20465.1 - 8.3e-10 38.5 0.0 2.1e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KKK20465.1 - 1.4e-09 37.3 0.1 2.4e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KKK20465.1 - 4.8e-09 36.3 0.0 0.00062 19.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK20465.1 - 1.6e-06 27.2 0.0 0.0077 15.1 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK20465.1 - 1.4e-05 24.9 0.1 0.13 12.0 0.0 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KKK20465.1 - 0.0024 16.8 0.0 0.5 9.2 0.0 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 KKK20465.1 - 0.014 14.2 0.0 0.35 9.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KKK20465.1 - 0.053 12.3 0.0 2.3 6.9 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK20465.1 - 0.062 12.3 0.1 1 8.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 KKK20465.1 - 0.069 11.3 0.0 0.75 7.8 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.9 KKK20465.1 - 0.16 10.4 0.0 11 4.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein VRR_NUC PF08774.6 KKK20466.1 - 1.1e-16 60.6 0.1 4.1e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 VRR-NUC domain Ribosomal_S13_N PF08069.7 KKK20467.1 - 9.3e-29 99.0 0.1 1.8e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KKK20467.1 - 1.1e-22 79.5 0.1 1.7e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KKK20467.1 - 0.015 15.0 0.1 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain YflT PF11181.3 KKK20467.1 - 0.099 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT 7tm_2 PF00002.19 KKK20468.1 - 3e-06 26.4 17.3 0.0001 21.4 10.4 2.1 1 1 0 2 2 2 2 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KKK20468.1 - 0.00081 18.3 19.1 0.0031 16.4 7.1 2.5 2 1 0 2 2 2 2 Slime mold cyclic AMP receptor RRM_1 PF00076.17 KKK20469.1 - 8.6e-27 92.5 0.0 1.4e-10 40.6 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK20469.1 - 7.7e-21 73.8 0.0 1.2e-05 25.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK20469.1 - 3.3e-11 42.8 0.0 1.6e-06 27.8 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ufm1 PF03671.9 KKK20469.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein Dpy-30 PF05186.8 KKK20470.1 - 0.00037 19.8 0.0 0.00046 19.5 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif PP1_bind PF15276.1 KKK20470.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.6 1 1 1 2 2 2 0 Protein phosphatase 1 binding RCR PF12273.3 KKK20483.1 - 0.005 17.3 3.9 0.022 15.3 2.7 2.0 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red GCC2_GCC3 PF07699.8 KKK20483.1 - 0.027 14.0 5.4 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 GCC2 and GCC3 Ribosomal_S27e PF01667.12 KKK20483.1 - 0.15 11.5 1.4 0.24 10.9 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein S27 FAM163 PF15069.1 KKK20483.1 - 0.66 10.5 3.4 1.6 9.3 0.1 2.7 3 0 0 3 3 3 0 FAM163 family Sas10_Utp3 PF04000.10 KKK20529.1 - 3.3e-16 59.2 0.2 6.8e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family PCI PF01399.22 KKK20530.1 - 0.044 14.0 0.0 9.7 6.5 0.0 2.9 3 0 0 3 3 3 0 PCI domain Peptidase_M3_N PF08439.5 KKK20530.1 - 0.14 12.2 0.2 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Oligopeptidase F 5_nucleotid_C PF02872.13 KKK20531.1 - 4.7e-36 124.1 0.0 7.9e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KKK20531.1 - 2.8e-08 33.4 0.0 4.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.17 KKK20532.1 - 1.3e-08 35.0 0.1 3.5e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) EMP70 PF02990.11 KKK20533.1 - 1.3e-188 627.7 0.6 1.8e-188 627.2 0.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 KKK20533.1 - 0.075 13.1 0.0 0.075 13.1 0.0 4.1 3 2 1 4 4 4 0 NfeD-like C-terminal, partner-binding NAD_binding_8 PF13450.1 KKK20534.1 - 1e-06 28.6 0.1 1.5e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KKK20534.1 - 1.4e-05 23.5 0.0 1.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.19 KKK20534.1 - 6e-05 22.1 0.3 7.1e-05 21.8 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KKK20534.1 - 0.00013 21.6 0.1 0.00016 21.3 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KKK20534.1 - 0.0029 17.3 0.1 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KKK20534.1 - 0.0032 17.5 0.1 0.0048 16.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK20534.1 - 0.0034 17.2 0.0 0.0041 17.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK20534.1 - 0.0047 17.2 0.4 0.0067 16.8 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK20534.1 - 0.011 14.5 0.3 0.013 14.3 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KKK20534.1 - 0.047 12.1 0.1 0.061 11.7 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 KKK20534.1 - 0.058 12.9 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 KKK20534.1 - 0.065 13.0 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 KKK20534.1 - 0.11 11.3 0.2 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A ELM2 PF01448.19 KKK20544.1 - 0.54 10.9 2.8 4.6 7.9 0.0 2.7 2 2 0 2 2 2 0 ELM2 domain MSA-2c PF12238.3 KKK20544.1 - 6 6.4 6.7 11 5.6 4.6 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pup PF05639.6 KKK20544.1 - 7.5 7.1 8.1 22 5.6 0.1 2.9 2 1 1 3 3 3 0 Pup-like protein G-patch PF01585.18 KKK20545.1 - 1.4e-11 43.9 0.7 2.7e-11 43.0 0.5 1.5 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.13 KKK20545.1 - 2.5e-10 39.2 1.9 5.9e-10 38.0 1.3 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KKK20545.1 - 1.6e-08 34.0 4.1 0.00024 20.6 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK20545.1 - 6.9e-06 25.9 0.0 0.0094 15.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KKK20545.1 - 8e-05 22.4 1.2 0.00026 20.7 0.8 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_5 PF13893.1 KKK20545.1 - 0.0096 15.7 0.3 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NCD3G PF07562.9 KKK20545.1 - 1.8 8.3 6.4 6 6.6 0.7 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Zn_clus PF00172.13 KKK20546.1 - 3.8e-08 33.0 11.3 8.5e-08 31.9 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Grp1_Fun34_YaaH PF01184.14 KKK20547.1 - 2.7e-22 79.1 13.5 3.7e-22 78.6 9.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.2 KKK20547.1 - 0.3 11.0 6.6 0.79 9.6 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) FxsA PF04186.8 KKK20547.1 - 2.3 7.8 8.0 4.6 6.8 0.1 2.4 2 1 0 2 2 2 0 FxsA cytoplasmic membrane protein Pectate_lyase_3 PF12708.2 KKK20548.1 - 4.5e-54 183.9 19.0 5.4e-43 147.7 1.4 3.1 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KKK20548.1 - 0.032 13.7 0.3 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase DUF3433 PF11915.3 KKK20549.1 - 1e-34 118.5 18.3 2.1e-26 91.8 2.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) RHINO PF15319.1 KKK20549.1 - 0.65 9.7 5.1 1.1 9.0 3.5 1.2 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Fungal_trans_2 PF11951.3 KKK20550.1 - 2.1e-09 36.5 1.2 1.4e-08 33.7 0.5 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20550.1 - 2.3e-08 33.7 8.8 4e-08 33.0 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C14 PF00656.17 KKK20551.1 - 6.9e-25 88.1 0.0 1e-24 87.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain TACC PF05010.9 KKK20551.1 - 0.21 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) CHAT PF12770.2 KKK20552.1 - 6.3e-65 219.1 0.4 1.2e-64 218.1 0.3 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 KKK20552.1 - 1.1e-07 31.6 8.6 0.017 15.0 0.0 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK20552.1 - 0.00049 19.5 7.8 6.9 6.4 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK20552.1 - 0.015 15.0 1.1 31 4.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 KKK20552.1 - 0.086 11.9 2.7 14 4.6 0.6 3.2 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.12 KKK20552.1 - 0.1 12.5 10.9 26 5.0 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK20552.1 - 0.44 10.4 4.1 11 6.0 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pyr_redox_3 PF13738.1 KKK20553.1 - 1.2e-19 71.1 0.0 4.3e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK20553.1 - 2.9e-14 52.1 0.2 2.7e-12 45.6 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KKK20553.1 - 2.4e-09 37.3 0.0 3.8e-08 33.4 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK20553.1 - 3.4e-09 36.0 0.0 6.3e-07 28.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK20553.1 - 3.3e-07 30.2 0.1 1.2e-05 25.1 0.0 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KKK20553.1 - 1.1e-05 24.6 0.1 3.5e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KKK20553.1 - 8.7e-05 22.8 0.6 0.31 11.4 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK20553.1 - 0.0033 16.3 1.2 0.0054 15.6 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KKK20553.1 - 0.0054 15.2 0.3 0.013 14.0 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 KKK20553.1 - 0.0054 15.6 0.1 0.13 11.1 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KKK20553.1 - 0.012 14.7 0.1 0.096 11.8 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KKK20553.1 - 0.017 15.2 0.2 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SnoaL_2 PF12680.2 KKK20553.1 - 0.019 15.3 0.0 0.16 12.4 0.0 2.4 2 0 0 2 2 2 0 SnoaL-like domain GIDA PF01134.17 KKK20553.1 - 0.022 13.6 0.8 0.23 10.2 0.3 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KKK20553.1 - 0.038 13.0 0.0 0.53 9.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family ADH_N PF08240.7 KKK20554.1 - 1.7e-30 104.9 2.7 3.7e-30 103.8 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK20554.1 - 9.9e-27 93.0 0.1 5.1e-26 90.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK20554.1 - 3.3e-07 31.2 0.0 7.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KKK20554.1 - 0.023 14.7 0.1 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK20554.1 - 0.076 12.8 0.3 0.17 11.7 0.2 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KKK20566.1 - 9.5e-13 47.9 0.7 1.5e-12 47.2 0.5 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KKK20566.1 - 4.5e-06 26.9 0.2 2.4e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK20566.1 - 2.2e-05 23.5 0.7 0.00018 20.5 0.2 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK20566.1 - 0.0005 20.0 0.1 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KKK20566.1 - 0.0018 17.4 0.2 0.0038 16.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK20566.1 - 0.0096 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KKK20566.1 - 0.013 15.4 0.1 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KKK20566.1 - 0.015 14.7 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KKK20566.1 - 0.02 13.7 0.2 0.047 12.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KKK20566.1 - 0.066 12.0 0.2 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KKK20566.1 - 0.099 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MutS_V PF00488.16 KKK20567.1 - 1.4e-94 315.9 0.0 2.2e-94 315.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KKK20567.1 - 2e-40 138.7 1.9 3.9e-40 137.8 1.3 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KKK20567.1 - 3.3e-20 72.5 0.4 2.9e-19 69.4 0.0 2.7 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 KKK20567.1 - 1.2e-16 60.6 0.9 3.8e-16 59.0 0.6 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 KKK20567.1 - 3.9e-14 52.6 0.0 2.3e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 MutS domain I Nucleoplasmin PF03066.10 KKK20568.1 - 0.0016 17.9 0.6 0.003 17.0 0.4 1.5 1 0 0 1 1 1 1 Nucleoplasmin Myc_N PF01056.13 KKK20568.1 - 0.0097 15.1 2.0 0.021 14.0 1.4 1.5 1 0 0 1 1 1 1 Myc amino-terminal region Lentiviral_Tat PF02998.9 KKK20568.1 - 0.013 15.3 0.2 0.083 12.7 0.1 2.2 2 0 0 2 2 2 0 Lentiviral Tat protein Sigma70_ner PF04546.8 KKK20568.1 - 0.015 14.9 2.7 0.14 11.7 1.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.7 KKK20568.1 - 0.049 11.5 4.5 0.07 11.0 3.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 KKK20568.1 - 0.05 12.3 7.1 0.086 11.5 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IFT57 PF10498.4 KKK20568.1 - 0.07 11.8 1.0 0.12 11.1 0.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-B_dimeris PF09026.5 KKK20568.1 - 0.11 12.7 8.9 0.22 11.7 6.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 KKK20568.1 - 0.11 10.3 5.8 0.18 9.6 4.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 KKK20568.1 - 0.19 10.9 2.5 0.28 10.3 1.8 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 KKK20568.1 - 0.2 11.9 4.0 0.48 10.7 2.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AF1Q PF15017.1 KKK20568.1 - 0.21 11.4 6.4 0.53 10.2 4.5 1.6 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator FAM176 PF14851.1 KKK20568.1 - 0.6 9.7 3.8 1.1 8.9 2.7 1.4 1 0 0 1 1 1 0 FAM176 family VID27 PF08553.5 KKK20568.1 - 1.3 7.1 5.3 1.8 6.6 3.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein TRAP_alpha PF03896.11 KKK20568.1 - 2.8 6.8 4.8 3.8 6.4 2.6 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Gpi1 PF05024.10 KKK20569.1 - 7.9e-62 208.2 8.7 7.9e-62 208.2 6.1 2.0 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Aldedh PF00171.17 KKK20570.1 - 1.3e-189 630.3 0.3 1.4e-189 630.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Vps51 PF08700.6 KKK20571.1 - 1.9e-17 62.8 3.4 1.9e-17 62.8 1.3 1.8 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 KKK20571.1 - 0.065 13.1 0.5 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 F-box-like PF12937.2 KKK20572.1 - 4.4e-10 39.1 0.2 9.4e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK20572.1 - 1.4e-09 37.3 0.8 3.6e-09 36.0 0.2 1.9 2 0 0 2 2 2 1 F-box domain DUF2014 PF09427.5 KKK20572.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Hira PF07569.6 KKK20572.1 - 0.23 10.6 0.2 22 4.1 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split Mre11_DNA_bind PF04152.9 KKK20573.1 - 4.5e-60 202.4 0.7 4.5e-60 202.4 0.5 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KKK20573.1 - 6.4e-26 90.9 2.5 9.2e-26 90.4 1.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zein PF01559.11 KKK20573.1 - 0.13 11.5 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Zein seed storage protein BAP PF06639.6 KKK20573.1 - 8.2 6.2 5.8 8.3 6.1 0.0 3.2 3 0 0 3 3 3 0 Basal layer antifungal peptide (BAP) MAS20 PF02064.10 KKK20574.1 - 1.4e-16 60.5 0.7 1e-11 44.8 0.4 2.6 2 1 0 2 2 2 2 MAS20 protein import receptor Glyco_hydro_72 PF03198.9 KKK20575.1 - 2.1e-118 394.9 1.0 2.9e-116 387.8 0.7 2.1 1 1 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KKK20575.1 - 5.4e-05 22.5 0.2 0.0088 15.2 0.0 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KKK20575.1 - 0.0085 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain RAP1 PF07218.6 KKK20575.1 - 2.1 6.3 10.0 3.7 5.5 4.7 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_6 PF12697.2 KKK20591.1 - 3.3e-05 23.8 0.1 3.3e-05 23.8 0.0 3.0 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK20591.1 - 0.0079 15.7 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 KKK20591.1 - 0.043 12.7 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 KKK20591.1 - 0.06 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ADH_N PF08240.7 KKK20592.1 - 4.3e-29 100.4 0.1 5.2e-29 100.1 0.1 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_L22 PF00237.14 KKK20593.1 - 7.4e-09 35.4 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e 2-Hacid_dh_C PF02826.14 KKK20594.1 - 1.3e-55 187.3 0.0 1.7e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK20594.1 - 4.1e-19 68.3 0.0 4.9e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KKK20594.1 - 0.00027 20.8 0.3 0.0019 18.0 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase HSF_DNA-bind PF00447.12 KKK20646.1 - 1.8e-38 130.8 0.4 3.4e-38 129.9 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KKK20646.1 - 3.3e-17 62.4 0.0 6.8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain CENP-Q PF13094.1 KKK20646.1 - 0.0072 16.3 6.3 0.016 15.2 4.4 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 KKK20646.1 - 0.16 12.3 7.7 0.16 12.3 3.8 2.2 2 0 0 2 2 2 0 SlyX W2 PF02020.13 KKK20647.1 - 1.3e-16 60.2 11.2 1.3e-16 60.2 7.8 2.6 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KKK20647.1 - 2e-10 39.6 11.5 1.5e-05 24.2 0.4 3.7 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK20647.1 - 5.5e-07 29.0 11.6 0.0044 16.5 0.2 4.1 1 1 3 4 4 4 4 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 KKK20647.1 - 6.7e-06 25.5 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KKK20647.1 - 0.0076 16.3 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain Keratin_assoc PF09775.4 KKK20647.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Band_7 PF01145.20 KKK20650.1 - 4.6e-31 108.1 0.6 1e-30 106.9 0.4 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KKK20650.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.6 1 1 0 1 1 1 0 SPFH domain-Band 7 family NPR3 PF03666.8 KKK20651.1 - 5.9e-137 456.8 1.6 1.6e-135 452.1 0.0 2.1 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Myc_N PF01056.13 KKK20651.1 - 0.0027 16.9 1.2 0.0065 15.6 0.8 1.5 1 0 0 1 1 1 1 Myc amino-terminal region NPR2 PF06218.6 KKK20651.1 - 0.063 11.9 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Nitrogen permease regulator 2 BLVR PF06375.6 KKK20651.1 - 0.16 11.7 10.2 1.3 8.8 2.2 3.0 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) NST1 PF13945.1 KKK20651.1 - 0.16 12.0 8.2 0.45 10.5 0.1 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator YchF-GTPase_C PF06071.8 KKK20652.1 - 4.3e-21 74.5 0.0 1e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KKK20652.1 - 5.7e-13 48.8 0.0 1.1e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK20652.1 - 0.00018 20.7 0.0 0.00038 19.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 KKK20652.1 - 0.015 15.1 0.0 0.045 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KKK20652.1 - 0.03 14.6 0.2 12 6.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KKK20652.1 - 0.044 13.5 0.2 2.6 7.8 0.0 2.8 1 1 1 3 3 3 0 Dynamin family AAA_17 PF13207.1 KKK20652.1 - 0.12 13.1 0.0 0.73 10.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KKK20652.1 - 0.12 12.0 0.5 3.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Hira PF07569.6 KKK20653.1 - 1.2e-83 279.6 0.0 2.2e-83 278.8 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 KKK20653.1 - 8.1e-36 120.6 16.3 1.4e-07 31.1 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 KKK20653.1 - 1.5e-10 40.3 0.1 3.5e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 KKK20653.1 - 5.6e-05 22.6 0.9 1.7 8.4 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KKK20653.1 - 0.076 10.8 0.0 0.44 8.3 0.0 1.9 2 0 0 2 2 2 0 IKI3 family Methyltransf_7 PF03492.10 KKK20695.1 - 6.4e-20 71.1 0.0 3.6e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 SAM dependent carboxyl methyltransferase Zn_clus PF00172.13 KKK20696.1 - 1.1e-10 41.2 9.8 2e-10 40.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK20696.1 - 0.022 13.6 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain FMN_dh PF01070.13 KKK20697.1 - 2.3e-114 381.9 0.2 2.8e-114 381.6 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KKK20697.1 - 9.4e-07 28.0 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KKK20697.1 - 0.00033 19.6 0.3 0.0008 18.3 0.1 1.7 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KKK20697.1 - 0.0017 17.6 0.2 0.0024 17.0 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 KKK20697.1 - 0.012 14.8 0.5 1.1 8.4 0.0 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 KKK20697.1 - 0.093 11.7 0.0 7.3 5.5 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Pkinase PF00069.20 KKK20700.1 - 3.6e-17 62.3 0.0 9.1e-17 61.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20700.1 - 0.00048 19.2 0.0 0.00073 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Metallophos PF00149.23 KKK20701.1 - 3.4e-08 33.1 1.7 1.4e-06 27.8 1.2 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK20701.1 - 0.00041 20.2 0.0 0.00099 18.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PI-PLC-X PF00388.14 KKK20703.1 - 3.6e-08 32.9 0.0 5.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain His_Phos_2 PF00328.17 KKK20704.1 - 1.1e-11 44.7 0.0 1.9e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.11 KKK20705.1 - 2.1e-05 23.4 0.7 2.2e-05 23.3 0.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20705.1 - 0.0004 19.0 0.1 0.00046 18.8 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK20706.1 - 1.5e-20 73.2 43.6 2.2e-20 72.6 30.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20706.1 - 0.0006 18.5 32.9 0.0024 16.4 22.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Helicase_C PF00271.26 KKK20708.1 - 7.7e-13 48.1 0.0 1.3e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK20708.1 - 0.0023 17.4 0.0 0.0065 15.9 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Fungal_trans_2 PF11951.3 KKK20709.1 - 1.8e-09 36.7 0.0 8.8e-09 34.4 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain CheD PF03975.8 KKK20709.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Zn_clus PF00172.13 KKK20709.1 - 0.27 11.1 2.5 0.51 10.3 1.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Rax2 PF12768.2 KKK20710.1 - 1.8e-107 358.7 19.3 4e-98 328.0 0.0 5.2 4 2 1 5 5 5 5 Cortical protein marker for cell polarity WD40 PF00400.27 KKK20710.1 - 0.28 11.1 2.9 38 4.3 0.0 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat eIF3_N PF09440.5 KKK20712.1 - 1.9e-52 176.9 0.9 3.9e-52 175.9 0.6 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KKK20712.1 - 5.2e-14 52.4 0.1 1.7e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain Cucumo_2B PF03263.8 KKK20712.1 - 0.0054 16.9 0.4 0.087 13.1 0.0 2.8 2 1 1 3 3 3 1 Cucumovirus protein 2B PCI_Csn8 PF10075.4 KKK20712.1 - 0.018 14.7 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 RPN7 PF10602.4 KKK20712.1 - 0.04 13.2 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Transthyretin PF00576.16 KKK20713.1 - 2.2e-22 79.0 0.0 9.2e-21 73.8 0.0 2.1 1 1 0 1 1 1 1 HIUase/Transthyretin family GPI-anchored PF10342.4 KKK20713.1 - 0.039 14.4 0.2 0.064 13.7 0.2 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ArsA_ATPase PF02374.10 KKK20714.1 - 6.9e-115 383.2 0.0 8e-115 383.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KKK20714.1 - 9.5e-17 61.0 0.2 1.6e-16 60.3 0.2 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KKK20714.1 - 4.4e-08 33.2 0.0 6.5e-07 29.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KKK20714.1 - 3.4e-06 26.4 0.1 9.1e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KKK20714.1 - 4.8e-05 22.8 0.3 0.0014 18.1 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KKK20714.1 - 0.0071 15.7 0.1 0.024 14.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK20714.1 - 0.008 15.9 0.0 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain MipZ PF09140.6 KKK20714.1 - 0.016 14.3 0.1 0.055 12.5 0.0 1.9 2 0 0 2 2 2 0 ATPase MipZ IstB_IS21 PF01695.12 KKK20714.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AIP3 PF03915.8 KKK20714.1 - 0.023 13.6 0.1 0.033 13.0 0.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 PhoH PF02562.11 KKK20714.1 - 0.024 13.8 0.1 0.064 12.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein YhjQ PF06564.7 KKK20714.1 - 0.038 13.3 0.0 0.096 12.0 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein NB-ARC PF00931.17 KKK20714.1 - 0.042 12.7 0.0 0.083 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 KKK20714.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin A1_Propeptide PF07966.7 KKK20714.1 - 0.27 11.1 1.7 0.43 10.4 0.1 2.3 2 0 0 2 2 2 0 A1 Propeptide bZIP_1 PF00170.16 KKK20715.1 - 2.2e-14 53.1 4.6 4.5e-14 52.1 3.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK20715.1 - 3.6e-07 29.8 4.7 9.3e-07 28.5 3.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK20715.1 - 0.0018 18.4 2.8 0.0018 18.4 2.0 2.0 1 1 1 2 2 2 1 bZIP Maf transcription factor Shugoshin_N PF07558.6 KKK20715.1 - 0.066 12.9 2.1 0.13 11.9 0.7 2.0 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region Ant_C PF05586.6 KKK20715.1 - 0.11 12.9 0.5 0.11 12.9 0.3 1.6 2 0 0 2 2 2 0 Anthrax receptor C-terminus region Phlebovirus_NSM PF07246.6 KKK20715.1 - 0.25 10.4 3.5 0.28 10.2 2.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Parvo_coat PF00740.13 KKK20715.1 - 0.48 9.3 5.0 0.56 9.0 3.4 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF3408 PF11888.3 KKK20715.1 - 3.6 7.5 6.7 5.5 6.9 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) ADIP PF11559.3 KKK20715.1 - 6.4 6.6 15.1 3.2 7.6 1.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Aft1_HRA PF11786.3 KKK20716.1 - 6.2e-29 100.0 11.1 6.2e-29 100.0 7.7 2.9 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 KKK20716.1 - 9.6e-23 81.0 2.2 9.6e-23 81.0 1.6 2.4 2 0 0 2 2 2 1 Aft1 HRR domain Aft1_OSA PF11785.3 KKK20716.1 - 1.5e-20 73.4 6.4 5.6e-20 71.6 4.4 2.0 1 0 0 1 1 1 1 Aft1 osmotic stress response (OSM) domain Img2 PF05046.9 KKK20717.1 - 1.1e-29 102.5 0.0 2.2e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.16 KKK20718.1 - 4.5e-21 74.4 0.5 1.6e-20 72.7 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain ICE2 PF08426.5 KKK20719.1 - 2e-144 481.2 13.9 2.3e-144 481.0 9.7 1.0 1 0 0 1 1 1 1 ICE2 FTHFS PF01268.14 KKK20719.1 - 0.17 9.8 0.0 0.25 9.2 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase tRNA-synt_1g PF09334.6 KKK20720.1 - 2.5e-142 474.1 0.0 3.1e-142 473.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KKK20720.1 - 4.4e-10 38.2 0.1 2.4e-06 25.8 0.0 3.8 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) OppC_N PF12911.2 KKK20720.1 - 0.062 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Elongin_A PF06881.6 KKK20720.1 - 0.074 13.4 1.5 0.19 12.0 1.1 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DZR PF12773.2 KKK20720.1 - 0.88 9.4 5.1 3.2 7.6 3.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon Yae1_N PF09811.4 KKK20721.1 - 1.1e-07 31.2 3.5 1.7e-07 30.6 2.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FSH1 PF03959.8 KKK20745.1 - 2.1e-30 105.7 0.0 1.1e-29 103.4 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) NAD_kinase PF01513.16 KKK20746.1 - 4.3e-39 133.9 0.0 1.2e-35 122.6 0.0 2.1 1 1 1 2 2 2 2 ATP-NAD kinase E1-E2_ATPase PF00122.15 KKK20747.1 - 5.3e-61 205.5 6.7 1.1e-60 204.5 4.6 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK20747.1 - 6.6e-34 117.0 1.2 6.6e-34 117.0 0.8 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK20747.1 - 2.6e-27 96.6 0.3 4.7e-26 92.5 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK20747.1 - 9.1e-15 53.8 0.0 9.1e-15 53.8 0.0 2.1 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KKK20747.1 - 2.4e-14 53.0 0.0 4.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK20747.1 - 2.1e-13 50.8 0.1 8.6e-13 48.8 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK20747.1 - 1.2e-06 28.2 2.2 4.6e-05 23.1 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 KKK20748.1 - 0.018 15.3 0.2 0.041 14.2 0.1 1.6 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 MBOAT_2 PF13813.1 KKK20749.1 - 5.9e-20 71.1 4.9 5.9e-20 71.1 3.4 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family APT PF03440.9 KKK20749.1 - 0.22 11.2 0.8 0.71 9.6 0.1 2.0 2 0 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain Amino_oxidase PF01593.19 KKK20750.1 - 3.4e-71 240.6 0.9 3.9e-71 240.4 0.6 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KKK20750.1 - 8.1e-08 32.1 0.1 2.4e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK20750.1 - 1.8e-05 24.8 0.8 0.028 14.4 0.5 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK20750.1 - 0.0027 17.4 0.5 1.4 8.7 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KKK20750.1 - 0.0046 16.0 2.2 0.038 13.0 0.2 3.0 4 0 0 4 4 4 1 FAD binding domain DAO PF01266.19 KKK20750.1 - 0.0096 14.8 5.2 0.77 8.5 0.3 2.9 3 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 KKK20750.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KKK20750.1 - 0.018 15.4 0.1 0.92 9.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK20750.1 - 0.04 13.7 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KKK20750.1 - 0.14 10.9 0.0 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KKK20750.1 - 0.15 12.1 0.1 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HMG_CoA_synt_C PF08540.5 KKK20751.1 - 1.3e-15 57.6 0.0 1.4e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Fungal_trans PF04082.13 KKK20753.1 - 2.1e-22 79.2 0.1 3.2e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20753.1 - 3.1e-10 39.7 9.1 4.6e-10 39.2 6.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KKK20754.1 - 1.2e-44 152.3 0.0 1.4e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RTA1 PF04479.8 KKK20755.1 - 2.9e-36 125.0 8.6 4.6e-36 124.4 6.0 1.3 1 0 0 1 1 1 1 RTA1 like protein ADH_zinc_N PF00107.21 KKK20755.1 - 2.9e-21 75.3 0.1 6.2e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK20755.1 - 1e-15 58.7 0.0 1.9e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK20755.1 - 2.5e-11 43.3 0.0 1.2e-10 41.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3671 PF12420.3 KKK20755.1 - 0.025 14.5 5.1 3.5 7.6 0.4 3.3 2 1 1 3 3 3 0 Protein of unknown function Aminotran_3 PF00202.16 KKK20755.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Hydrolase_6 PF13344.1 KKK20756.1 - 1.1e-23 83.0 0.0 2.1e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK20756.1 - 8.1e-18 63.9 0.0 2.1e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KKK20756.1 - 0.0074 16.7 0.0 0.12 12.7 0.0 2.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KKK20756.1 - 0.011 15.9 0.0 0.91 9.7 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.16 KKK20757.1 - 2.9e-56 190.3 0.0 3.4e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MSA-2c PF12238.3 KKK20758.1 - 0.062 12.9 2.2 0.1 12.2 1.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c RRM_1 PF00076.17 KKK20759.1 - 6.5e-18 64.1 0.0 8.6e-18 63.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK20759.1 - 2.2e-14 53.1 0.0 3.3e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK20759.1 - 3.1e-09 36.5 0.0 4.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK20759.1 - 0.001 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ATP-synt_Eps PF04627.8 KKK20760.1 - 2.9e-23 81.1 0.9 4.4e-23 80.5 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF676 PF05057.9 KKK20761.1 - 5.4e-06 25.8 0.0 4.1e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KKK20761.1 - 0.0014 18.2 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KKK20761.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KKK20761.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Mak10 PF04112.8 KKK20763.1 - 5.9e-58 194.7 0.0 1.1e-57 193.8 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Cpn60_TCP1 PF00118.19 KKK20764.1 - 2.1e-118 396.0 6.2 2.4e-118 395.8 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 KKK20764.1 - 0.19 11.4 1.6 0.57 9.8 0.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) TPMT PF05724.6 KKK20766.1 - 4.8e-23 81.7 0.0 2.2e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KKK20766.1 - 6.7e-07 29.8 0.0 1.1e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK20766.1 - 2.8e-06 27.1 0.0 4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK20766.1 - 0.00032 20.3 0.0 0.29 10.7 0.1 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KKK20766.1 - 0.00044 20.6 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK20766.1 - 0.0018 18.5 0.0 0.0046 17.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK20766.1 - 0.04 14.3 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 KKK20767.1 - 2.9e-11 42.7 0.6 7e-11 41.4 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20767.1 - 5.9e-10 38.9 8.9 1.1e-09 38.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KKK20768.1 - 2.3e-25 89.4 0.1 4.9e-25 88.3 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK20768.1 - 7.6e-14 52.0 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK20768.1 - 3.8e-12 46.2 0.4 3e-11 43.2 0.3 2.3 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KKK20768.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK20768.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 KKK20768.1 - 0.059 13.6 0.0 0.18 12.0 0.0 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding DAOA PF15199.1 KKK20768.1 - 0.16 12.6 0.0 0.26 11.9 0.0 1.4 1 0 0 1 1 1 0 D-amino acid oxidase activator Mito_carr PF00153.22 KKK20770.1 - 2.8e-63 209.6 1.6 5.1e-20 70.9 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 KKK20771.1 - 3.2e-09 36.3 0.1 6.4e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK20771.1 - 4.4e-06 26.1 0.1 1.1e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 KKK20771.1 - 0.019 14.8 0.4 0.042 13.7 0.3 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 KKK20771.1 - 0.04 13.5 0.9 0.092 12.4 0.6 1.6 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 KKK20771.1 - 0.094 12.6 0.7 1.1 9.3 0.7 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat EXS PF03124.9 KKK20772.1 - 1.7e-97 326.5 9.7 1.9e-97 326.3 6.7 1.0 1 0 0 1 1 1 1 EXS family RhoGAP PF00620.22 KKK20773.1 - 8.7e-16 57.8 0.1 1.9e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KKK20773.1 - 6.5e-12 45.4 0.0 3.2e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KKK20773.1 - 8.7e-11 41.4 0.0 1.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AA_permease PF00324.16 KKK20774.1 - 3.3e-118 395.0 39.8 8.2e-118 393.7 23.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KKK20774.1 - 1.3e-27 96.4 35.9 1.8e-27 95.9 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease LSM PF01423.17 KKK20775.1 - 1.5e-14 53.2 0.0 1.7e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 KKK20776.1 - 2.5e-22 79.1 0.1 3.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease KOW PF00467.24 KKK20777.1 - 3.3e-06 26.6 1.1 7.9e-06 25.3 0.7 1.6 1 0 0 1 1 1 1 KOW motif DUF2423 PF10338.4 KKK20777.1 - 0.037 14.0 0.4 0.071 13.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) DUF1223 PF06764.6 KKK20777.1 - 0.046 13.5 0.1 0.052 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) GTP_EFTU_D2 PF03144.20 KKK20777.1 - 0.085 12.9 0.4 0.24 11.5 0.2 1.8 1 1 1 2 2 2 0 Elongation factor Tu domain 2 AAA_14 PF13173.1 KKK20778.1 - 0.0005 19.9 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK20778.1 - 0.007 17.1 0.0 0.015 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KKK20778.1 - 0.091 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sigma54_activ_2 PF14532.1 KKK20778.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 KKK20778.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 KKK20778.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KKK20778.1 - 0.17 11.8 0.0 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 KKK20778.1 - 0.23 11.0 0.0 0.5 9.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Pex2_Pex12 PF04757.9 KKK20779.1 - 1.7e-43 148.6 9.4 2.1e-43 148.3 6.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KKK20779.1 - 3.2e-11 42.8 9.8 5.2e-11 42.1 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK20779.1 - 5.6e-11 41.9 6.1 8.1e-11 41.4 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK20779.1 - 6.1e-11 42.1 9.2 1e-10 41.4 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK20779.1 - 1.4e-10 40.5 7.2 2.3e-10 39.9 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK20779.1 - 2.4e-08 33.5 7.2 4e-08 32.8 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KKK20779.1 - 6.6e-06 25.9 8.2 1.2e-05 25.0 5.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KKK20779.1 - 7.1e-06 25.6 2.2 9.8e-06 25.1 0.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KKK20779.1 - 0.00027 20.9 8.0 0.00066 19.7 5.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KKK20779.1 - 0.0019 17.9 3.2 0.0034 17.1 2.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KKK20779.1 - 0.053 13.3 3.7 0.11 12.2 2.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KKK20779.1 - 0.054 13.0 7.4 0.1 12.2 5.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KKK20779.1 - 0.066 12.7 3.9 0.14 11.6 2.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.16 KKK20779.1 - 1.1 9.1 7.1 4.2 7.3 5.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 KKK20779.1 - 1.4 8.8 8.2 6.2 6.7 5.7 1.9 1 1 0 1 1 1 0 IBR domain VHS PF00790.14 KKK20797.1 - 1.4e-43 147.9 0.0 5.5e-43 145.9 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KKK20797.1 - 3.1e-25 88.0 0.3 8.9e-25 86.5 0.2 1.8 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KKK20797.1 - 5.7e-22 78.1 0.1 1.1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF935 PF06074.7 KKK20797.1 - 1.1 7.9 6.3 1.7 7.2 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Aldo_ket_red PF00248.16 KKK20799.1 - 5e-42 143.6 0.0 2.6e-37 128.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family zf-H2C2_2 PF13465.1 KKK20800.1 - 5.5e-07 29.5 8.9 1.2e-06 28.5 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK20800.1 - 2.5e-05 24.2 9.4 0.00031 20.8 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK20800.1 - 3.1e-05 24.0 0.3 3.1e-05 24.0 0.2 3.7 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KKK20800.1 - 0.018 14.9 0.3 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK20800.1 - 0.14 12.3 3.8 1.2 9.3 0.3 3.4 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding UCR_hinge PF02320.11 KKK20801.1 - 4.8e-23 80.8 6.7 5.5e-23 80.6 4.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.4 KKK20801.1 - 1.2 9.1 6.2 5.1 7.2 4.3 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 KKK20801.1 - 1.7 8.6 5.8 2.7 8.0 0.6 2.4 2 0 0 2 2 2 0 CHCH domain Toxin_2 PF00451.14 KKK20801.1 - 7.6 6.7 6.2 2.4 8.3 0.2 2.5 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 PIP5K PF01504.13 KKK20803.1 - 2.6e-59 200.3 0.1 6e-59 199.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KKK20803.1 - 1.5e-26 93.1 0.0 2.2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KKK20803.1 - 1.4e-14 53.6 4.0 1.4e-14 53.6 2.8 1.9 2 0 0 2 2 2 1 FYVE zinc finger XPC-binding PF09280.6 KKK20803.1 - 0.093 12.1 0.5 0.23 10.9 0.3 1.6 1 0 0 1 1 1 0 XPC-binding domain TPP1 PF10341.4 KKK20804.1 - 0.00088 19.2 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD TRAM_LAG1_CLN8 PF03798.11 KKK20805.1 - 2.3e-50 170.9 18.8 2.3e-50 170.9 13.0 1.9 2 0 0 2 2 2 1 TLC domain SR-25 PF10500.4 KKK20805.1 - 9.6 5.6 6.2 17 4.7 4.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_L27e PF01777.13 KKK20807.1 - 5.1e-39 132.2 2.6 6.7e-39 131.9 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KKK20807.1 - 0.00015 21.3 1.2 0.00026 20.5 0.2 2.0 2 0 0 2 2 2 1 KOW motif RCC1 PF00415.13 KKK20808.1 - 1.4e-61 204.4 5.9 3.1e-12 46.5 0.1 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KKK20808.1 - 4.4e-33 112.1 40.9 2.8e-09 36.3 0.9 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH_5 PF14567.1 KKK20808.1 - 0.11 11.9 0.0 19 4.7 0.0 3.5 4 0 0 4 4 4 0 SMI1-KNR4 cell-wall uDENN PF03456.13 KKK20808.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 uDENN domain Transp_cyt_pur PF02133.10 KKK20809.1 - 2.5e-49 168.0 39.9 2.8e-49 167.8 27.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin eIF3g PF12353.3 KKK20810.1 - 1.6e-46 157.3 2.8 2.4e-46 156.7 2.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KKK20810.1 - 3.2e-17 61.9 0.0 5.4e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK20810.1 - 9.4e-14 51.1 0.0 2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK20810.1 - 3.1e-08 33.3 0.0 6.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) A_deamin PF02137.13 KKK20810.1 - 0.061 12.6 0.1 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain NDT80_PhoG PF05224.7 KKK20811.1 - 8e-26 91.1 0.1 1.1e-25 90.7 0.1 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Beta-lactamase PF00144.19 KKK20812.1 - 1.9e-44 152.0 0.0 4.2e-44 150.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Methyltransf_23 PF13489.1 KKK20814.1 - 9.6e-13 48.1 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK20814.1 - 4.6e-09 36.0 0.0 5.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK20814.1 - 7.3e-09 36.0 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK20814.1 - 3.5e-07 30.7 0.0 5.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK20814.1 - 2.4e-06 26.8 0.0 3.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KKK20814.1 - 4.1e-06 27.1 0.0 6.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KKK20814.1 - 7e-06 24.9 0.0 1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 KKK20814.1 - 0.00035 20.5 0.0 0.00094 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK20814.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KKK20814.1 - 0.0034 16.9 0.0 0.043 13.3 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_24 PF13578.1 KKK20814.1 - 0.025 15.3 0.0 0.052 14.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain NMO PF03060.10 KKK20815.1 - 8.1e-60 202.7 4.6 2.4e-58 197.8 3.2 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KKK20815.1 - 8.6e-08 31.4 0.4 4.3e-07 29.1 0.3 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KKK20815.1 - 2.1e-05 23.5 1.5 3.5e-05 22.8 1.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KKK20815.1 - 0.016 14.2 0.2 0.028 13.3 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 KKK20815.1 - 0.021 13.7 1.3 0.045 12.6 0.9 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase Radial_spoke_3 PF06098.6 KKK20815.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Pterin_bind PF00809.17 KKK20816.1 - 9.6e-53 178.6 0.0 2.8e-51 173.8 0.0 2.4 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KKK20816.1 - 1.2e-35 121.9 0.0 2.2e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) AHS2 PF02626.10 KKK20817.1 - 6e-76 255.3 0.0 8.2e-76 254.8 0.0 1.2 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KKK20817.1 - 5.5e-54 182.6 0.0 9.3e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KKK20817.1 - 3.9e-34 116.8 0.0 6.7e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KKK20817.1 - 6.8e-28 96.9 0.0 1.7e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain AHS1 PF02682.11 KKK20817.1 - 9.4e-16 57.8 0.0 1.5e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 ATP-grasp_4 PF13535.1 KKK20817.1 - 7e-15 55.2 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KKK20817.1 - 1.1e-11 44.0 0.0 1.7e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK20817.1 - 5.7e-06 25.8 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 KKK20817.1 - 0.017 14.6 0.0 0.045 13.2 0.0 1.7 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp PF02222.17 KKK20817.1 - 0.027 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.1 KKK20817.1 - 0.027 13.6 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Homeobox_KN PF05920.6 KKK20818.1 - 5.5e-16 57.9 0.8 1.5e-15 56.6 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_4 PF13894.1 KKK20818.1 - 4e-05 23.6 16.3 0.0045 17.2 1.1 4.9 3 1 0 3 3 3 2 C2H2-type zinc finger Homeobox PF00046.24 KKK20818.1 - 0.00027 20.4 0.5 0.00063 19.3 0.4 1.7 1 0 0 1 1 1 1 Homeobox domain HTH_Tnp_Tc5 PF03221.11 KKK20818.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HA PF03457.9 KKK20818.1 - 0.013 15.6 0.1 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 Helicase associated domain zf-C2H2 PF00096.21 KKK20818.1 - 0.035 14.4 19.7 0.42 11.0 0.9 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF605 PF04652.11 KKK20818.1 - 0.28 10.5 4.9 0.49 9.7 3.4 1.3 1 0 0 1 1 1 0 Vta1 like 2OG-FeII_Oxy_2 PF13532.1 KKK20819.1 - 4.7e-34 117.9 0.0 6.6e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KKK20819.1 - 0.00021 21.1 5.3 0.00036 20.3 3.6 1.4 1 0 0 1 1 1 1 GRF zinc finger DUF1444 PF07285.6 KKK20819.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) UQ_con PF00179.21 KKK20820.1 - 2.8e-10 39.7 0.2 5e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KKK20820.1 - 0.0097 15.7 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain LicD PF04991.8 KKK20822.1 - 3e-36 125.4 7.1 3.6e-35 121.9 4.9 2.2 1 1 0 1 1 1 1 LicD family Fungal_trans PF04082.13 KKK20823.1 - 4.6e-07 28.9 0.1 7.7e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20823.1 - 0.00057 19.7 11.7 0.00099 18.9 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clathrin PF00637.15 KKK20824.1 - 7.4e-23 80.7 5.8 1.9e-20 72.9 1.9 2.7 2 1 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 KKK20824.1 - 1.9e-20 72.4 0.1 4.6e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal TPR_14 PF13428.1 KKK20824.1 - 0.00051 20.4 0.1 0.41 11.4 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.1 KKK20824.1 - 0.0045 16.7 6.0 0.0097 15.7 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.1 KKK20824.1 - 0.0057 16.2 0.6 0.023 14.3 0.1 2.3 2 0 0 2 2 2 1 TPR repeat zf-C3HC4 PF00097.20 KKK20824.1 - 0.013 15.1 2.6 0.027 14.1 1.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK20824.1 - 0.015 15.4 2.6 0.029 14.4 1.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 KKK20824.1 - 0.029 14.1 5.3 0.06 13.0 3.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KKK20824.1 - 0.052 13.5 5.4 0.11 12.5 3.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 KKK20824.1 - 0.26 11.2 10.4 0.27 11.1 0.4 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK20824.1 - 0.26 11.1 7.0 0.05 13.3 0.3 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-Apc11 PF12861.2 KKK20824.1 - 0.3 10.9 1.4 0.68 9.8 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_16 PF13432.1 KKK20824.1 - 0.59 10.8 3.4 0.57 10.9 0.2 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK20824.1 - 9.6 6.4 10.9 0.15 12.0 0.2 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.16 KKK20826.1 - 2.7e-28 98.0 0.0 7e-28 96.7 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KKK20826.1 - 1.4e-06 28.1 44.8 0.0006 19.7 10.9 2.7 2 0 0 2 2 2 2 Chitin recognition protein HEAT_2 PF13646.1 KKK20827.1 - 1.7e-07 31.4 0.0 4.7e-05 23.5 0.0 3.3 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 KKK20827.1 - 3.3e-06 26.7 2.1 0.092 12.8 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.2 KKK20827.1 - 0.011 16.0 0.0 0.22 11.9 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KKK20827.1 - 0.013 15.9 6.7 10 6.7 0.0 4.8 4 2 3 7 7 7 0 HEAT-like repeat Adaptin_N PF01602.15 KKK20827.1 - 0.024 13.0 0.0 14 3.8 0.0 2.9 2 1 1 3 3 3 0 Adaptin N terminal region DUF2435 PF10363.4 KKK20827.1 - 0.027 14.3 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) UME PF08064.8 KKK20827.1 - 0.033 14.1 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 UME (NUC010) domain DRIM PF07539.7 KKK20827.1 - 0.04 13.3 0.0 0.11 11.8 0.0 1.8 1 1 0 1 1 1 0 Down-regulated in metastasis Cnd1 PF12717.2 KKK20827.1 - 0.061 13.1 0.0 1 9.1 0.0 2.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 IL13 PF03487.8 KKK20827.1 - 2.7 7.7 5.0 0.59 9.8 0.2 2.4 3 0 0 3 3 3 0 Interleukin-13 TRAM_LAG1_CLN8 PF03798.11 KKK20828.1 - 7.1e-37 126.8 19.3 7.1e-37 126.8 13.4 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KKK20828.1 - 2.6e-22 78.0 0.0 2.6e-22 78.0 0.0 2.1 2 1 0 2 2 2 1 TRAM1-like protein DUF4492 PF14899.1 KKK20828.1 - 0.013 14.9 0.1 0.034 13.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Thioredoxin_4 PF13462.1 KKK20828.1 - 0.014 15.3 0.1 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin TFIIE-A_C-term PF11521.3 KKK20828.1 - 0.14 12.1 1.4 0.24 11.3 1.0 1.4 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha OPT PF03169.10 KKK20829.1 - 1e-166 556.0 54.4 1.1e-166 555.8 37.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.19 KKK20830.1 - 3.3e-21 75.6 0.1 2.6e-20 72.6 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK20830.1 - 0.079 12.9 0.7 0.21 11.6 0.5 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KKK20830.1 - 0.085 12.9 0.0 0.98 9.5 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KKK20830.1 - 0.095 12.1 1.0 0.17 11.2 0.7 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KKK20830.1 - 0.096 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF604 PF04646.7 KKK20830.1 - 0.15 11.2 0.4 0.25 10.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Transglut_core PF01841.14 KKK20832.1 - 5e-12 46.0 0.0 8.8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 KKK20832.1 - 0.014 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like domain Tox-PL PF15644.1 KKK20832.1 - 0.069 13.9 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 Papain fold toxin 1 Sugar_tr PF00083.19 KKK20833.1 - 2.3e-113 379.1 21.1 2.7e-113 378.9 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK20833.1 - 1.2e-25 89.9 32.3 1.6e-23 83.0 16.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK20833.1 - 9e-06 24.3 9.8 6.9e-05 21.4 0.8 3.3 4 0 0 4 4 4 2 MFS/sugar transport protein DUF4470 PF14737.1 KKK20834.1 - 2.7e-24 84.7 0.0 5.6e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) KTI12 PF08433.5 KKK20839.1 - 1.6e-62 211.1 0.0 7.2e-62 209.0 0.0 2.0 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KKK20839.1 - 7e-06 25.9 0.2 3.2e-05 23.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain Methyltransf_16 PF10294.4 KKK20840.1 - 4.8e-14 52.1 0.0 6.6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KKK20840.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain zf-C2H2 PF00096.21 KKK20841.1 - 0.097 13.0 2.6 2 8.9 0.0 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK20841.1 - 0.55 10.6 15.6 0.6 10.5 0.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Histone PF00125.19 KKK20856.1 - 2e-27 95.1 0.2 2.9e-27 94.6 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KKK20856.1 - 0.0012 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KKK20856.1 - 0.048 13.7 0.4 0.1 12.7 0.3 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KKK20856.1 - 0.09 12.0 0.2 0.1 11.8 0.1 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DER1 PF04511.10 KKK20857.1 - 2.7e-51 173.8 3.8 3.1e-51 173.7 2.6 1.0 1 0 0 1 1 1 1 Der1-like family Transp_cyt_pur PF02133.10 KKK20858.1 - 1.1e-29 103.3 32.6 6e-29 100.8 22.1 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.16 KKK20858.1 - 0.00012 21.3 0.0 0.00028 20.0 0.0 1.8 1 1 1 2 2 2 1 Cation efflux family DUF4131 PF13567.1 KKK20858.1 - 0.15 11.4 0.1 0.15 11.4 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Methyltransf_2 PF00891.13 KKK20859.1 - 3.8e-16 59.0 0.0 2.2e-15 56.5 0.0 1.9 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 KKK20859.1 - 2.2e-05 24.2 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.21 KKK20861.1 - 9.5e-32 110.4 0.0 1.1e-31 110.2 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MFS_1 PF07690.11 KKK20862.1 - 2.2e-16 59.5 41.2 2.2e-16 59.5 28.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Adaptin_N PF01602.15 KKK20864.1 - 6.3e-112 374.5 0.1 8.2e-112 374.1 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KKK20864.1 - 1.5e-59 200.1 3.6 1.5e-59 200.1 2.5 2.0 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KKK20864.1 - 2e-14 53.6 2.2 0.00011 22.3 0.0 6.4 2 2 3 5 5 5 4 HEAT repeats Cnd1 PF12717.2 KKK20864.1 - 0.0044 16.8 6.6 0.045 13.6 0.3 3.7 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 KKK20864.1 - 0.0046 17.3 1.9 12 6.7 0.0 5.0 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat DUF1548 PF07579.6 KKK20864.1 - 0.098 12.7 0.6 0.68 10.0 0.1 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) HEAT PF02985.17 KKK20864.1 - 0.11 12.5 8.9 30 5.0 0.1 5.7 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.1 KKK20864.1 - 1 9.9 3.7 3.1 8.4 0.3 3.3 3 0 0 3 3 3 0 HEAT-like repeat TFIID-18kDa PF02269.11 KKK20865.1 - 5.5e-23 80.5 0.0 1.3e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 KKK20865.1 - 0.0078 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KKK20865.1 - 0.033 14.3 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S TAF PF02969.12 KKK20865.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 KKK20865.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CD99L2 PF12301.3 KKK20865.1 - 4.4 6.9 16.0 2.4 7.8 3.4 2.2 2 0 0 2 2 2 0 CD99 antigen like protein 2 PPR_2 PF13041.1 KKK20866.1 - 6.8e-11 41.9 4.2 0.00065 19.6 0.1 4.4 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 KKK20866.1 - 2.9e-09 36.4 5.2 0.33 11.3 0.1 7.2 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 KKK20866.1 - 0.0025 17.6 0.2 0.84 9.7 0.0 4.0 4 0 0 4 4 4 1 PPR repeat ATP13 PF12921.2 KKK20866.1 - 0.064 12.6 0.3 0.21 10.9 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial ATPase expression zf-CCHC_3 PF13917.1 KKK20867.1 - 0.014 15.0 2.2 0.016 14.9 0.2 2.1 2 0 0 2 2 2 0 Zinc knuckle cwf18 PF08315.7 KKK20868.1 - 7.4e-44 149.3 4.9 7.4e-44 149.3 3.4 1.5 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Fungal_trans PF04082.13 KKK20873.1 - 3.8e-28 98.0 5.7 7.7e-28 97.0 3.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol_Rpb2_6 PF00562.23 KKK20874.1 - 9.1e-124 413.0 0.1 1.8e-123 412.1 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KKK20874.1 - 7e-62 207.9 0.0 1.1e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KKK20874.1 - 2.5e-46 157.5 0.0 4.6e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KKK20874.1 - 2.7e-30 104.4 0.0 7e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KKK20874.1 - 3.1e-24 84.5 0.8 6.8e-24 83.4 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KKK20874.1 - 2.4e-23 81.8 0.5 5.5e-23 80.6 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 KKK20874.1 - 4.5e-23 80.7 0.6 1.5e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 CTNNBL PF08216.6 KKK20875.1 - 2.7e-34 116.9 0.9 1.9e-33 114.2 0.2 2.6 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KKK20875.1 - 0.00023 20.8 1.2 0.48 10.3 0.0 3.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KKK20875.1 - 0.0074 16.5 8.2 0.085 13.1 0.2 4.2 3 1 1 4 4 4 1 HEAT repeats Pico_P1A PF02226.11 KKK20875.1 - 0.028 14.1 0.1 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) Mo25 PF08569.6 KKK20875.1 - 0.029 13.4 0.5 0.14 11.1 0.1 2.3 1 1 1 2 2 2 0 Mo25-like MMS19_C PF12460.3 KKK20875.1 - 0.039 12.6 0.3 0.54 8.9 0.0 2.4 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Desmo_N PF06771.6 KKK20875.1 - 0.17 11.7 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus RNA_pol_Rpc34 PF05158.7 KKK20876.1 - 7.2e-123 409.9 0.0 8.1e-123 409.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.14 KKK20876.1 - 0.042 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 KKK20876.1 - 0.072 12.7 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 MarR family TrmE_N PF10396.4 KKK20876.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus HTH_36 PF13730.1 KKK20876.1 - 0.098 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_11 PF13414.1 KKK20877.1 - 1.3e-55 184.9 17.5 2e-18 65.7 0.2 6.4 3 3 4 7 7 7 7 TPR repeat TPR_1 PF00515.23 KKK20877.1 - 3e-39 131.0 18.7 3.3e-05 23.2 0.1 8.9 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KKK20877.1 - 5.7e-32 107.0 21.5 2.7e-05 23.7 0.2 9.8 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 KKK20877.1 - 1.5e-21 76.1 13.6 8.9e-08 31.9 0.1 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KKK20877.1 - 9.7e-18 64.3 11.2 0.0055 17.3 0.2 6.6 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KKK20877.1 - 1.2e-12 47.2 15.1 0.24 12.1 0.3 9.3 4 3 6 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK20877.1 - 8.3e-12 44.0 13.4 0.043 13.6 0.0 7.0 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KKK20877.1 - 1.9e-10 40.9 16.0 0.1 12.9 0.0 7.0 4 3 2 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KKK20877.1 - 7.4e-09 35.1 4.5 1.9 8.8 0.0 7.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 KKK20877.1 - 7.8e-08 32.0 12.6 0.0005 19.8 0.1 5.0 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KKK20877.1 - 1.2e-07 31.0 13.9 0.02 14.6 0.2 8.5 9 1 0 9 9 8 1 Tetratricopeptide repeat Apc3 PF12895.2 KKK20877.1 - 5.3e-07 29.6 7.2 0.0011 19.0 0.1 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 KKK20877.1 - 5.3e-05 23.0 0.8 0.21 11.4 0.0 4.9 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 KKK20877.1 - 0.0007 18.7 7.9 1.8 7.8 0.0 5.2 6 0 0 6 6 6 2 SHNi-TPR NARP1 PF12569.3 KKK20877.1 - 0.016 13.9 0.1 0.016 13.9 0.0 3.9 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 Inhibitor_I9 PF05922.11 KKK20877.1 - 0.022 15.3 0.2 0.091 13.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase inhibitor I9 TPR_6 PF13174.1 KKK20877.1 - 0.038 14.4 18.8 1.3 9.6 0.0 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK20877.1 - 0.11 12.5 8.8 39 4.3 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 KKK20877.1 - 0.12 12.5 0.1 0.12 12.5 0.1 5.6 4 2 3 7 7 7 0 Tetratricopeptide repeat NAPRTase PF04095.11 KKK20878.1 - 1.1e-56 191.8 0.0 1.5e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family ING PF12998.2 KKK20879.1 - 5.8e-24 84.3 7.3 1.1e-23 83.4 5.1 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KKK20879.1 - 7.1e-09 35.2 9.7 1.2e-08 34.4 6.8 1.4 1 0 0 1 1 1 1 PHD-finger DUF4200 PF13863.1 KKK20879.1 - 0.029 14.2 4.9 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FGF-BP1 PF06473.7 KKK20879.1 - 1.5 8.3 8.4 0.35 10.4 3.1 1.9 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) zf-RING-like PF08746.6 KKK20879.1 - 4.4 7.3 7.6 9.6 6.2 5.2 1.6 1 0 0 1 1 1 0 RING-like domain RR_TM4-6 PF06459.7 KKK20882.1 - 3.3 7.5 8.2 4.5 7.0 5.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_hydro_32N PF00251.15 KKK20883.1 - 1.5e-95 320.1 3.7 1.9e-95 319.7 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KKK20883.1 - 4e-20 71.9 0.4 1.4e-19 70.2 0.1 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KKK20883.1 - 0.0023 17.4 1.0 0.024 14.3 0.7 2.9 1 0 0 1 1 1 1 BNR/Asp-box repeat DUF3304 PF11745.3 KKK20884.1 - 0.59 10.3 5.3 0.13 12.4 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3304) Sec23_trunk PF04811.10 KKK20885.1 - 5.6e-57 192.8 0.0 9e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KKK20885.1 - 3.4e-25 87.4 0.0 6.2e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KKK20885.1 - 3e-18 66.1 0.0 5.5e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KKK20885.1 - 5.1e-17 61.1 6.5 9.5e-17 60.2 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KKK20885.1 - 3.7e-07 29.7 0.0 7.3e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.1 KKK20885.1 - 0.00035 20.0 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator CPSF100_C PF13299.1 KKK20886.1 - 4.2e-46 157.0 0.3 8.1e-46 156.1 0.0 1.7 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KKK20886.1 - 8.7e-27 93.5 0.0 1.5e-25 89.5 0.0 2.7 3 0 0 3 3 3 1 Beta-Casp domain RMMBL PF07521.7 KKK20886.1 - 0.00053 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KKK20886.1 - 0.0063 16.1 0.6 0.037 13.6 0.4 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PGM_PMM_IV PF00408.15 KKK20886.1 - 0.0081 16.1 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AA_permease_2 PF13520.1 KKK20887.1 - 1.1e-52 179.0 48.9 1.5e-52 178.6 33.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK20887.1 - 8e-16 57.4 39.2 1.1e-15 56.9 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease Ofd1_CTDD PF10637.4 KKK20889.1 - 3.2e-106 354.3 0.0 1.4e-99 332.5 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KKK20889.1 - 2.9e-16 59.8 0.0 6.6e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KKK20889.1 - 0.037 13.6 1.1 0.35 10.5 0.0 3.0 2 2 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily AAA_12 PF13087.1 KKK20890.1 - 2.3e-36 125.0 0.0 3.6e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK20890.1 - 9.2e-23 81.0 0.0 4.8e-22 78.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK20890.1 - 1.7e-07 30.8 0.0 3.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KKK20890.1 - 4e-06 26.5 0.1 0.00024 20.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KKK20890.1 - 3.9e-05 23.2 0.0 0.018 14.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KKK20890.1 - 0.0019 17.7 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 KKK20890.1 - 0.0066 15.7 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 KKK20890.1 - 0.03 13.3 0.1 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ParA PF10609.4 KKK20890.1 - 0.061 13.2 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 ParA/MinD ATPase like IstB_IS21 PF01695.12 KKK20890.1 - 0.074 12.4 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KKK20890.1 - 0.083 12.2 0.0 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 KKK20890.1 - 0.1 12.2 0.0 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Helicase ResIII PF04851.10 KKK20890.1 - 0.11 12.3 0.0 0.44 10.3 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KKK20890.1 - 0.17 11.1 0.1 0.5 9.6 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF3445 PF11927.3 KKK20891.1 - 7.5e-78 261.3 0.0 1.1e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans PF04082.13 KKK20892.1 - 2.2e-15 56.2 0.8 3.3e-15 55.6 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK20892.1 - 8.1e-07 29.0 9.4 0.00024 21.2 2.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK20892.1 - 2e-06 27.8 2.5 2e-06 27.8 1.7 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK20892.1 - 2.7e-06 27.3 8.6 0.00091 19.3 2.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK20892.1 - 0.039 14.1 1.7 0.055 13.6 0.4 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PRP38 PF03371.10 KKK20894.1 - 7.8e-67 224.2 0.0 9.7e-67 223.9 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Pkinase PF00069.20 KKK20895.1 - 0.00082 18.5 0.0 0.001 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20895.1 - 0.051 12.6 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase WD40 PF00400.27 KKK20896.1 - 2.8e-20 71.3 3.4 0.038 13.8 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nop14 PF04147.7 KKK20896.1 - 0.75 7.6 9.7 1.1 7.1 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family Glypican PF01153.14 KKK20896.1 - 2.3 6.7 3.1 3.3 6.1 2.1 1.1 1 0 0 1 1 1 0 Glypican WSC PF01822.14 KKK20897.1 - 1.6e-06 27.8 14.3 1.6e-06 27.8 9.9 3.5 2 1 0 2 2 2 1 WSC domain Podoplanin PF05808.6 KKK20897.1 - 2.3e-06 27.2 7.0 3.8e-06 26.5 4.8 1.4 1 0 0 1 1 1 1 Podoplanin IncA PF04156.9 KKK20897.1 - 0.051 13.1 0.1 0.095 12.2 0.1 1.4 1 0 0 1 1 1 0 IncA protein TrbL PF04610.9 KKK20897.1 - 0.23 11.1 4.9 0.13 11.9 1.7 1.9 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Trp_oprn_chp PF09534.5 KKK20897.1 - 0.28 10.7 4.8 0.16 11.5 1.6 1.9 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1206 PF06724.6 KKK20897.1 - 5.1 6.9 9.3 1.3 8.8 3.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) TMEM154 PF15102.1 KKK20897.1 - 5.1 6.7 8.3 20 4.8 5.8 2.0 1 1 0 1 1 1 0 TMEM154 protein family Sugar_tr PF00083.19 KKK20905.1 - 2.4e-23 82.4 15.4 2.6e-23 82.3 10.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK20905.1 - 3.6e-07 29.2 10.0 4.2e-07 29.0 6.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane_2 PF12679.2 KKK20905.1 - 0.29 9.9 10.4 0.35 9.6 7.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein CrtC PF07143.6 KKK20906.1 - 2.4e-10 40.2 0.4 6.2e-10 38.8 0.3 1.6 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) CENP-F_leu_zip PF10473.4 KKK20919.1 - 0.0041 16.9 43.6 0.3 10.9 4.5 4.3 2 1 2 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KKK20919.1 - 1 8.4 10.9 0.94 8.5 0.6 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_p24 PF05073.7 KKK20919.1 - 1.9 8.0 18.9 0.077 12.5 2.1 3.0 3 0 0 3 3 3 0 Baculovirus P24 capsid protein APG6 PF04111.7 KKK20919.1 - 2.8 6.9 53.8 0.09 11.8 11.8 3.7 2 1 1 3 3 3 0 Autophagy protein Apg6 RNA_pol_Rpb5_C PF01191.14 KKK20920.1 - 5.6e-35 118.7 0.1 1.1e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KKK20920.1 - 9.7e-34 115.6 0.1 1.5e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KKK20920.1 - 0.039 13.7 0.0 0.093 12.5 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease Glyco_hydro_3 PF00933.16 KKK20922.1 - 6.2e-88 294.6 0.0 9.4e-88 294.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK20922.1 - 9.8e-63 211.7 0.0 1.5e-61 207.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK20922.1 - 4e-23 81.1 0.4 2e-22 78.9 0.1 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KKK20922.1 - 0.0037 16.9 0.0 0.0079 15.8 0.0 1.6 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.6 KKK20922.1 - 0.045 13.8 0.1 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 CARDB Aminotran_1_2 PF00155.16 KKK20923.1 - 4.6e-59 200.2 0.0 5.6e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KKK20923.1 - 0.0015 16.8 0.0 0.0024 16.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 KKK20923.1 - 0.048 12.2 0.0 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 Allinase GCN5L1 PF06320.8 KKK20924.1 - 2.8e-11 43.3 0.6 3.9e-11 42.8 0.4 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Plasmid_stabil PF05016.9 KKK20924.1 - 0.021 15.1 1.3 0.073 13.4 0.0 2.0 1 1 0 2 2 2 0 Plasmid stabilisation system protein Raftlin PF15250.1 KKK20924.1 - 0.15 10.5 2.1 0.17 10.3 1.4 1.0 1 0 0 1 1 1 0 Raftlin AKAP7_RIRII_bdg PF10470.4 KKK20924.1 - 7.4 6.4 9.3 3.2 7.6 4.2 2.2 2 1 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein MutL_C PF08676.6 KKK20925.1 - 5.9e-23 81.0 0.1 1.4e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain ThiF PF00899.16 KKK20926.1 - 2.1e-28 98.8 0.0 3.4e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KKK20926.1 - 0.00087 19.4 0.0 0.0024 17.9 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KKK20926.1 - 0.079 12.3 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KKK20926.1 - 0.12 11.5 0.0 0.57 9.3 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FtsJ PF01728.14 KKK20927.1 - 1.3e-35 122.9 0.0 7.9e-35 120.4 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase GAS PF13851.1 KKK20927.1 - 6.4 5.9 30.9 0.0082 15.3 8.7 3.0 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding OST3_OST6 PF04756.8 KKK20929.1 - 6.6e-20 71.2 2.5 8.5e-20 70.9 1.7 1.1 1 0 0 1 1 1 1 OST3 / OST6 family VIT1 PF01988.14 KKK20929.1 - 0.024 14.1 11.0 0.18 11.2 1.1 2.1 1 1 1 2 2 2 0 VIT family DEAD PF00270.24 KKK20930.1 - 1.5e-47 161.2 0.1 1.2e-46 158.3 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK20930.1 - 1e-28 99.0 0.1 5.9e-27 93.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK20930.1 - 8.6e-06 25.7 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KKK20930.1 - 0.00051 19.1 0.1 0.00051 19.1 0.1 2.3 3 1 1 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 KKK20930.1 - 0.011 14.1 0.0 0.62 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Fungal_trans PF04082.13 KKK20931.1 - 6.8e-13 48.0 0.0 1.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med14 PF08638.6 KKK20932.1 - 4.5e-78 260.9 0.0 8.5e-78 260.0 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.3 KKK20933.1 - 1.7e-214 712.7 20.4 1.9e-214 712.5 14.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KKK20933.1 - 6.1e-11 41.6 41.0 1e-10 40.9 9.0 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Mfp-3 PF04202.8 KKK20933.1 - 0.062 13.4 0.1 12 6.1 0.2 2.6 2 0 0 2 2 2 0 Foot protein 3 Thioredoxin PF00085.15 KKK20934.1 - 3.6e-61 203.3 5.4 1.6e-31 108.0 0.1 4.4 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.1 KKK20934.1 - 8.2e-53 178.9 1.2 6.9e-40 136.8 0.1 3.6 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KKK20934.1 - 3.6e-10 39.8 0.0 0.00094 19.2 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 KKK20934.1 - 3.8e-10 39.0 1.6 1.5e-09 37.1 1.1 1.9 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.1 KKK20934.1 - 3.6e-09 36.8 3.1 0.0024 18.0 0.2 3.8 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KKK20934.1 - 1.4e-08 34.5 0.1 0.01 15.8 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 KKK20934.1 - 6.3e-07 29.1 2.5 0.0046 16.6 0.1 3.2 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KKK20934.1 - 8.6e-07 28.5 3.1 0.22 11.0 0.0 3.4 3 0 0 3 3 3 3 Redoxin Thioredoxin_4 PF13462.1 KKK20934.1 - 0.38 10.7 6.1 12 5.8 0.1 4.0 4 0 0 4 4 4 0 Thioredoxin UDG PF03167.14 KKK20935.1 - 3.3e-24 85.0 0.1 6e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DWNN PF08783.6 KKK20936.1 - 3.3e-33 113.4 0.9 5.1e-33 112.8 0.0 1.8 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.1 KKK20936.1 - 7e-06 25.4 7.3 1.7e-05 24.2 5.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KKK20936.1 - 0.018 14.9 1.2 0.018 14.9 0.8 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-Nse PF11789.3 KKK20936.1 - 0.21 11.1 3.9 0.47 10.0 2.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 KKK20936.1 - 1.7 8.3 8.7 3.8 7.2 6.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KKK20936.1 - 7.5 6.5 10.0 19 5.2 6.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KKK20936.1 - 7.9 6.2 13.0 0.52 10.0 4.8 2.1 2 1 0 2 2 2 0 zinc-RING finger domain Yippee-Mis18 PF03226.9 KKK20937.1 - 4.1e-23 81.2 0.1 6.4e-23 80.6 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 KKK20937.1 - 0.013 15.3 0.3 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I Transp_Tc5_C PF04236.10 KKK20937.1 - 0.054 13.7 0.6 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-ribbon_3 PF13248.1 KKK20937.1 - 0.11 11.7 1.9 0.97 8.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain SHNi-TPR PF10516.4 KKK20938.1 - 1.7e-17 62.3 2.3 9.8e-17 59.9 0.1 2.8 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 KKK20938.1 - 6.4e-08 32.1 2.7 0.0025 17.4 0.0 2.8 2 1 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 KKK20938.1 - 2.3e-07 30.6 7.8 0.00071 19.4 0.1 3.1 4 0 0 4 4 3 2 Tetratricopeptide repeat CCDC-167 PF15188.1 KKK20938.1 - 0.00019 21.3 1.1 0.00069 19.5 0.7 1.9 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 TPR_1 PF00515.23 KKK20938.1 - 0.0014 18.0 2.4 0.38 10.4 0.8 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK20938.1 - 0.079 13.6 6.9 10 6.9 2.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK20938.1 - 0.13 12.1 11.9 2.2 8.3 1.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK20938.1 - 0.14 12.8 2.1 53 4.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Creb_binding PF09030.5 KKK20938.1 - 0.25 11.5 5.1 0.053 13.7 0.7 2.1 2 0 0 2 2 2 0 Creb binding MIT PF04212.13 KKK20938.1 - 0.49 10.3 6.8 0.28 11.0 1.6 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain XhlA PF10779.4 KKK20938.1 - 9.7 6.1 7.9 12 5.9 0.9 3.1 2 1 0 2 2 2 0 Haemolysin XhlA DNA_pol_E_B PF04042.11 KKK20939.1 - 3.5e-50 170.1 0.0 4.7e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B dCMP_cyt_deam_1 PF00383.17 KKK20940.1 - 7.2e-27 93.0 1.5 1.1e-26 92.3 1.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 KKK20940.1 - 0.0021 18.3 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK20940.1 - 0.011 16.4 0.1 0.026 15.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain CoaE PF01121.15 KKK20940.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase His_biosynth PF00977.16 KKK20941.1 - 1e-48 165.5 0.7 4.8e-48 163.4 0.5 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KKK20941.1 - 1.7e-29 102.6 0.0 2.8e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KKK20941.1 - 5e-12 45.8 0.0 2.4e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KKK20941.1 - 2.2e-08 33.8 0.0 1.4e-07 31.2 0.0 2.2 3 0 0 3 3 3 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 KKK20941.1 - 0.0011 18.3 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Dus PF01207.12 KKK20941.1 - 0.0021 16.9 0.0 0.0046 15.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 KKK20941.1 - 0.086 11.8 0.9 0.12 11.4 0.1 1.5 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Roughex PF06020.6 KKK20943.1 - 0.18 10.4 3.5 0.35 9.5 2.4 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Dynamin_N PF00350.18 KKK20944.1 - 5.9e-12 45.7 0.0 2.3e-11 43.7 0.0 2.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KKK20944.1 - 3.4e-06 26.9 0.0 0.00085 19.2 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase DUF258 PF03193.11 KKK20944.1 - 8.6e-06 25.0 0.1 0.00011 21.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK20944.1 - 2.2e-05 24.5 0.0 2.2e-05 24.5 0.0 3.3 3 1 1 4 4 4 1 AAA ATPase domain ABC_tran PF00005.22 KKK20944.1 - 0.00028 21.1 0.2 0.0037 17.5 0.0 2.7 2 0 0 2 2 2 1 ABC transporter TraB PF01963.12 KKK20944.1 - 0.0052 16.2 0.7 0.015 14.7 0.5 1.7 1 0 0 1 1 1 1 TraB family AAA_29 PF13555.1 KKK20944.1 - 0.0084 15.6 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 KKK20944.1 - 0.012 16.1 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Guanylate_kin PF00625.16 KKK20944.1 - 0.026 13.9 0.2 0.46 9.9 0.0 2.7 3 0 0 3 3 3 0 Guanylate kinase AAA_10 PF12846.2 KKK20944.1 - 0.034 13.5 0.5 2.3 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KKK20944.1 - 0.036 14.2 2.1 0.16 12.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 KKK20944.1 - 0.052 12.9 0.0 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF939_C PF11728.3 KKK20944.1 - 0.082 12.7 3.5 0.29 10.9 0.1 3.0 3 0 0 3 3 3 0 DUF939 C-terminal domain UPF0016 PF01169.14 KKK20945.1 - 3.1e-41 139.3 25.3 3.6e-21 75.0 5.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 MFS_1 PF07690.11 KKK20946.1 - 1.3e-40 139.1 14.5 1.3e-40 139.1 10.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20946.1 - 2.2e-14 52.9 6.4 2.2e-14 52.9 4.5 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Cu_bind_like PF02298.12 KKK20947.1 - 0.061 13.1 1.1 0.11 12.3 0.0 2.0 3 0 0 3 3 3 0 Plastocyanin-like domain Podoplanin PF05808.6 KKK20947.1 - 0.066 12.7 1.1 0.078 12.5 0.0 1.6 2 0 0 2 2 2 0 Podoplanin Syndecan PF01034.15 KKK20947.1 - 0.13 11.9 0.7 0.23 11.1 0.5 1.3 1 0 0 1 1 1 0 Syndecan domain VSP PF03302.8 KKK20947.1 - 0.14 10.7 1.8 0.24 10.0 1.3 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein MtrF PF09472.5 KKK20947.1 - 1.9 7.7 6.6 3.1 7.0 4.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SSP160 PF06933.6 KKK20947.1 - 2.7 5.8 14.3 1.4 6.8 3.4 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.11 KKK20948.1 - 0.0001 21.1 36.4 0.00024 19.9 21.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KKK20955.1 - 3.4e-08 32.6 12.8 3.4e-08 32.6 8.9 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK20955.1 - 4.1e-05 21.9 8.7 5.3e-05 21.6 6.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF788 PF05620.6 KKK20955.1 - 0.026 14.3 4.5 0.047 13.5 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF998 PF06197.8 KKK20955.1 - 0.5 9.6 22.2 0.36 10.1 4.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF998) DUF3546 PF12066.3 KKK20963.1 - 1.3e-25 89.5 0.5 1.3e-25 89.5 0.4 2.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 KKK20963.1 - 9.4e-24 82.7 0.2 2.1e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 KKK20963.1 - 1.3e-11 45.1 1.2 2.4e-11 44.2 0.2 1.9 1 1 0 1 1 1 1 Arsenite-resistance protein 2 Fungal_trans PF04082.13 KKK20964.1 - 1.1e-07 31.0 1.2 1.7e-07 30.3 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20964.1 - 2.2e-06 27.4 9.9 5.1e-06 26.2 6.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TrmE_N PF10396.4 KKK20965.1 - 9.2e-36 122.2 0.1 2.5e-35 120.9 0.0 1.8 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 KKK20965.1 - 1.6e-16 60.2 0.0 2.8e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 KKK20965.1 - 4.1e-13 49.5 0.3 1.4e-12 47.8 0.2 1.9 1 1 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE GTP_EFTU PF00009.22 KKK20965.1 - 1.2e-05 24.8 0.0 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KKK20965.1 - 3.9e-05 22.9 0.0 0.00019 20.7 0.0 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KKK20965.1 - 8.6e-05 22.4 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KKK20965.1 - 0.00034 21.1 0.0 0.0011 19.4 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Glyco_hydro_3_C PF01915.17 KKK20965.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain cobW PF02492.14 KKK20965.1 - 0.077 12.4 0.0 1.4 8.2 0.0 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KKK20965.1 - 0.12 11.8 0.2 8.7 5.9 0.0 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_24 PF13479.1 KKK20965.1 - 0.15 11.6 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 KKK20966.1 - 2.5e-83 274.5 11.7 8.3e-21 74.1 0.1 7.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KKK20966.1 - 4.8e-75 243.8 28.2 8.7e-08 31.6 0.0 14.0 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 KKK20966.1 - 1.7e-55 184.4 18.4 3e-09 37.1 0.0 8.6 6 1 2 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK20966.1 - 2.7e-50 163.3 17.1 0.00026 20.9 0.0 14.5 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.1 KKK20966.1 - 5.4e-47 156.7 23.9 3.3e-08 33.5 0.2 11.4 2 2 10 12 12 12 11 Ankyrin repeats (many copies) Aconitase PF00330.15 KKK20967.1 - 4.7e-69 233.0 0.3 3.6e-43 147.7 0.0 2.6 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KKK20967.1 - 1.2e-24 86.8 0.0 2e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain FAD_binding_6 PF00970.19 KKK20967.1 - 6.2e-07 29.4 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KKK20967.1 - 9.3e-06 26.1 0.0 0.045 14.3 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KKK20967.1 - 0.0074 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain AA_permease_2 PF13520.1 KKK20968.1 - 2e-64 217.7 40.1 3.6e-64 216.8 27.8 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK20968.1 - 1.7e-28 99.2 24.1 1.7e-28 99.2 16.7 2.2 2 0 0 2 2 2 2 Amino acid permease MFS_1 PF07690.11 KKK20999.1 - 1.1e-25 90.0 35.0 1.3e-23 83.2 16.6 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20999.1 - 2.9e-09 36.0 14.3 2.9e-09 36.0 9.9 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 KKK20999.1 - 5.6e-06 25.0 15.5 5.6e-06 25.0 10.7 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 KKK21000.1 - 6.2e-24 84.3 29.9 9.4e-17 60.7 9.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK21000.1 - 3.2e-18 65.5 7.0 1.4e-17 63.4 4.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Methyltransf_11 PF08241.7 KKK21001.1 - 6.8e-15 55.3 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK21001.1 - 1.5e-13 50.7 0.0 2.2e-13 50.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK21001.1 - 3.2e-13 50.2 0.0 4.9e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK21001.1 - 8.1e-13 48.6 0.0 1.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK21001.1 - 2.5e-11 43.3 0.0 3.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK21001.1 - 4.8e-09 35.8 0.0 6.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KKK21001.1 - 1.7e-08 34.7 0.0 4e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK21001.1 - 4.4e-08 33.1 0.0 8.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KKK21001.1 - 4.3e-06 26.4 0.0 1.1e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 KKK21001.1 - 5.8e-06 25.5 0.0 8.9e-06 24.9 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 KKK21001.1 - 1.4e-05 24.0 0.0 2.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 KKK21001.1 - 1.8e-05 23.9 0.0 2.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 KKK21001.1 - 3.2e-05 23.4 0.0 6e-05 22.5 0.0 1.4 2 0 0 2 2 2 1 Nodulation protein S (NodS) PrmA PF06325.8 KKK21001.1 - 0.00022 20.4 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 KKK21001.1 - 0.00061 18.7 0.0 0.00084 18.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 KKK21001.1 - 0.0051 15.9 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.6 KKK21001.1 - 0.0067 15.8 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) FtsJ PF01728.14 KKK21001.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 KKK21001.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KKK21001.1 - 0.08 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.12 KKK21001.1 - 0.14 11.2 0.0 0.26 10.2 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase zf-DHHC PF01529.15 KKK21002.1 - 1.2e-33 115.9 2.0 2.5e-33 114.9 1.4 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KKK21002.1 - 0.094 12.5 3.5 0.21 11.4 2.4 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily DNA_mis_repair PF01119.14 KKK21003.1 - 1.5e-11 43.7 0.0 3.4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KKK21003.1 - 1.9e-11 43.6 0.1 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KKK21003.1 - 3.5e-09 36.4 0.1 1e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF202 PF02656.10 KKK21005.1 - 2.3e-18 66.1 0.4 4.2e-18 65.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) MBOAT_2 PF13813.1 KKK21006.1 - 1.2e-19 70.1 5.4 2.7e-19 69.0 3.8 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4137 PF13593.1 KKK21007.1 - 5.2e-87 291.8 19.3 6e-87 291.6 13.4 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 KKK21007.1 - 2.4e-08 33.6 4.6 2.4e-08 33.6 3.2 2.0 2 1 0 2 2 2 1 Sodium Bile acid symporter family Mito_carr PF00153.22 KKK21008.1 - 5e-68 224.8 3.7 2.2e-22 78.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein bZIP_2 PF07716.10 KKK21009.1 - 5e-11 42.2 17.1 5e-11 42.2 11.9 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KKK21009.1 - 1.6e-05 24.7 17.3 3.5e-05 23.6 12.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KKK21009.1 - 0.00039 20.6 14.9 0.00082 19.6 10.3 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Spc24 PF08286.6 KKK21009.1 - 0.024 14.3 1.2 0.057 13.1 0.8 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 APG6 PF04111.7 KKK21009.1 - 0.54 9.2 11.1 0.87 8.5 7.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3638 PF12340.3 KKK21024.1 - 1.6e-90 302.0 1.8 2.3e-90 301.5 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KKK21024.1 - 5.1e-14 51.1 0.0 9e-14 50.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) MFS_1 PF07690.11 KKK21026.1 - 3.3e-33 114.8 27.0 3.3e-33 114.8 18.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEMspv1-c74-12 PF11044.3 KKK21026.1 - 0.16 11.5 0.0 0.65 9.5 0.0 2.1 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein adh_short PF00106.20 KKK21027.1 - 4e-25 88.6 0.0 5.1e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK21027.1 - 5.6e-24 85.2 0.0 7.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK21027.1 - 2.5e-07 30.5 0.0 5.9e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KKK21027.1 - 0.1 12.4 1.2 0.24 11.2 0.6 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Kp4 PF09044.5 KKK21027.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Kp4 DAO PF01266.19 KKK21028.1 - 1.2e-28 100.0 0.0 1.4e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK21028.1 - 0.0006 18.7 0.0 0.00087 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK21028.1 - 0.00088 19.2 0.2 0.0026 17.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KKK21028.1 - 0.025 13.6 0.3 0.038 13.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KKK21028.1 - 0.045 14.1 0.1 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sulfotransfer_3 PF13469.1 KKK21028.1 - 0.052 14.4 0.2 0.096 13.6 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase family Pyr_redox_2 PF07992.9 KKK21028.1 - 0.097 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK21028.1 - 0.11 11.5 0.1 0.11 11.5 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Aa_trans PF01490.13 KKK21029.1 - 1.6e-27 96.0 44.4 3.5e-14 52.1 9.1 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein K1 PF02960.9 KKK21029.1 - 0.54 10.3 0.0 0.54 10.3 0.0 2.9 2 1 0 2 2 2 0 K1 glycoprotein Aldolase_II PF00596.16 KKK21030.1 - 2e-34 118.8 0.0 2.5e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.3 KKK21030.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Zn_clus PF00172.13 KKK21031.1 - 2.7e-07 30.3 10.8 6.3e-07 29.1 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 KKK21032.1 - 4.6e-28 98.0 0.0 7.4e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK21032.1 - 1.2e-17 63.9 0.0 2.2e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_2 PF13532.1 KKK21034.1 - 6.3e-31 107.7 0.0 3.3e-30 105.3 0.0 1.9 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Cupin_6 PF12852.2 KKK21034.1 - 0.0043 16.7 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 2 Cupin 2OG-FeII_Oxy_3 PF13640.1 KKK21034.1 - 0.021 15.3 0.0 0.066 13.7 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ADH_zinc_N PF00107.21 KKK21035.1 - 2.5e-11 43.2 0.0 7.2e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK21035.1 - 1.9e-05 24.3 0.1 3.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FAD_binding_3 PF01494.14 KKK21036.1 - 2.9e-19 69.3 0.2 2.5e-18 66.2 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK21036.1 - 6.2e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK21036.1 - 0.0003 19.8 0.0 1.9 7.2 0.0 3.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK21036.1 - 0.00031 21.1 0.0 0.24 11.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK21036.1 - 0.001 19.1 0.0 0.0071 16.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK21036.1 - 0.0022 17.1 0.0 0.053 12.5 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KKK21036.1 - 0.0047 15.8 0.0 0.09 11.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KKK21036.1 - 0.096 11.5 0.1 0.94 8.3 0.1 2.2 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KKK21036.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M35 PF02102.10 KKK21037.1 - 1.1e-58 198.5 7.7 1.6e-58 198.1 5.4 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KKK21037.1 - 4.1e-07 30.6 1.6 7e-07 29.8 1.1 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase PhageMin_Tail PF10145.4 KKK21037.1 - 0.00056 19.6 0.6 0.0015 18.2 0.4 1.7 2 0 0 2 2 2 1 Phage-related minor tail protein 2OG-FeII_Oxy_2 PF13532.1 KKK21038.1 - 1.2e-29 103.5 0.0 2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIG-L PF02585.12 KKK21039.1 - 7e-20 71.8 0.2 1.1e-19 71.2 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase WD40 PF00400.27 KKK21045.1 - 1.5e-25 88.1 17.2 6.8e-10 38.4 0.3 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 KKK21045.1 - 0.00058 19.6 0.0 0.025 14.2 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A zf-rbx1 PF12678.2 KKK21045.1 - 0.041 13.9 7.1 0.053 13.6 0.2 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger PRK PF00485.13 KKK21052.1 - 2.3e-08 33.8 0.0 3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KKK21052.1 - 1.2e-07 32.5 0.1 2.7e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK21052.1 - 9.9e-07 29.1 0.1 3.8e-06 27.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KKK21052.1 - 2.8e-05 24.0 1.0 0.012 15.5 0.1 2.7 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KKK21052.1 - 5.1e-05 22.4 0.6 0.00015 20.9 0.1 1.9 2 0 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.12 KKK21052.1 - 0.0014 18.0 0.2 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase SRP54 PF00448.17 KKK21052.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KKK21052.1 - 0.0026 17.4 0.1 0.0057 16.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KKK21052.1 - 0.0029 17.7 0.1 0.0071 16.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK21052.1 - 0.0059 16.7 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK21052.1 - 0.0071 16.3 0.8 0.019 14.9 0.6 1.9 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KKK21052.1 - 0.0089 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.1 KKK21052.1 - 0.017 14.7 0.6 0.036 13.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KKK21052.1 - 0.021 14.5 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_11 PF13086.1 KKK21052.1 - 0.025 14.1 0.0 0.071 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 KKK21052.1 - 0.025 13.3 0.1 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein 6PF2K PF01591.13 KKK21052.1 - 0.051 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ADH_N PF08240.7 KKK21053.1 - 2.1e-11 43.5 0.0 3.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK21053.1 - 3.3e-07 29.9 0.0 5.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KKK21054.1 - 4.3e-19 68.4 0.1 1.3e-18 66.8 0.0 1.7 1 1 0 2 2 2 1 Fungal specific transcription factor domain DUF1685 PF07939.6 KKK21054.1 - 0.13 11.8 0.0 1.3 8.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1685) Zn_clus PF00172.13 KKK21055.1 - 0.0052 16.6 5.6 0.035 14.0 3.9 2.2 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ_CXXCXGXG PF00684.14 KKK21055.1 - 0.14 12.2 2.3 0.22 11.5 1.6 1.4 1 0 0 1 1 1 0 DnaJ central domain NmrA PF05368.8 KKK21056.1 - 2.2e-17 63.0 0.0 3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK21056.1 - 1.1e-12 48.3 0.0 6.9e-12 45.7 0.0 2.2 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KKK21056.1 - 3.6e-08 33.1 0.1 9.3e-08 31.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK21056.1 - 2.2e-05 24.2 0.1 3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KKK21056.1 - 3.1e-05 23.1 0.1 4.2e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KKK21056.1 - 0.00017 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KKK21056.1 - 0.00089 19.2 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KKK21056.1 - 0.0032 16.2 0.1 0.0053 15.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 KKK21056.1 - 0.0064 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 KKK21056.1 - 0.0076 15.1 0.2 0.014 14.2 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.13 KKK21056.1 - 0.025 14.6 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Polysacc_synt_2 PF02719.10 KKK21056.1 - 0.037 12.9 0.3 0.074 11.9 0.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KKK21056.1 - 0.037 14.3 0.1 0.09 13.0 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain B12-binding PF02310.14 KKK21056.1 - 0.085 12.7 0.1 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 B12 binding domain ApbA PF02558.11 KKK21056.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 KKK21056.1 - 0.16 11.8 0.6 0.33 10.8 0.3 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Aminotran_5 PF00266.14 KKK21057.1 - 3.3e-29 101.7 0.0 9.5e-19 67.3 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V HEAT PF02985.17 KKK21058.1 - 2.2e-12 45.9 11.0 0.00024 20.9 0.1 9.0 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 KKK21058.1 - 4.8e-11 42.8 12.1 8.9e-09 35.5 0.1 6.8 7 2 1 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.1 KKK21058.1 - 6.7e-11 42.3 9.0 1.5e-05 25.1 0.0 6.5 3 2 3 6 6 6 4 HEAT repeats IBN_N PF03810.14 KKK21058.1 - 1.3e-08 34.6 5.1 2.3e-08 33.8 0.1 3.8 5 0 0 5 5 5 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KKK21058.1 - 1e-05 25.0 3.0 0.54 9.5 0.0 5.1 3 1 2 5 5 5 2 CLASP N terminal HEAT_PBS PF03130.11 KKK21058.1 - 0.00035 20.7 0.0 6.7 7.4 0.0 5.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Arm PF00514.18 KKK21058.1 - 0.0044 16.8 0.6 4.8 7.1 0.0 3.3 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Apc4 PF12896.2 KKK21059.1 - 5.6e-70 234.9 2.9 7.7e-70 234.4 2.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Gly_transf_sug PF04488.10 KKK21061.1 - 7.6e-20 71.2 0.1 1.3e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KKK21061.1 - 0.013 14.6 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 KKK21061.1 - 0.26 9.7 4.8 1.7 7.0 0.3 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF4139 PF13598.1 KKK21062.1 - 1.7e-54 185.3 1.7 2.6e-38 132.0 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KKK21062.1 - 5.6e-10 39.6 1.7 5.6e-10 39.6 1.2 3.8 3 1 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 KKK21062.1 - 0.0078 16.4 22.9 0.028 14.6 15.9 1.9 1 1 0 1 1 1 1 Nucleoporin FG repeat region ATP-synt_C PF00137.16 KKK21063.1 - 2.9e-14 52.6 10.8 4.2e-14 52.1 7.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit C DUF1772 PF08592.6 KKK21064.1 - 2e-34 118.3 4.6 2.3e-34 118.1 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) NnrS PF05940.7 KKK21064.1 - 0.024 13.5 3.8 0.026 13.4 2.6 1.1 1 0 0 1 1 1 0 NnrS protein TMEM237 PF15383.1 KKK21064.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 BTB PF00651.26 KKK21065.1 - 2.4e-13 50.0 0.1 4.5e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain DUF2987 PF11205.3 KKK21065.1 - 0.049 13.2 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) DUF4307 PF14155.1 KKK21065.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) LETM1 PF07766.8 KKK21066.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 LETM1-like protein Arylesterase PF01731.15 KKK21067.1 - 8.7e-05 22.4 0.0 0.0014 18.5 0.0 2.7 3 0 0 3 3 3 1 Arylesterase WD40 PF00400.27 KKK21090.1 - 1.8e-75 246.3 10.6 7.5e-13 47.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KKK21090.1 - 2.8e-13 49.8 5.0 4.2e-13 49.2 3.5 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 KKK21090.1 - 9.6e-06 24.1 1.3 0.00045 18.6 0.1 2.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 KKK21090.1 - 8.9e-05 20.8 0.1 0.07 11.2 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KKK21090.1 - 0.00021 21.0 0.0 0.031 14.0 0.0 2.9 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KKK21090.1 - 0.0097 15.0 0.0 4.1 6.4 0.0 2.9 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 KKK21090.1 - 0.029 13.8 1.0 3.5 7.0 0.3 2.9 2 1 1 3 3 3 0 PQQ-like domain Sec8_exocyst PF04048.9 KKK21102.1 - 0.066 12.8 0.3 9.2 5.8 0.0 2.7 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Baculo_PEP_C PF04513.7 KKK21102.1 - 0.1 12.4 11.6 0.15 11.8 0.3 3.7 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2135 PF09906.4 KKK21102.1 - 0.16 11.9 0.4 0.47 10.4 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) zf-MYND PF01753.13 KKK21103.1 - 0.015 15.1 8.8 0.043 13.7 6.1 1.8 1 0 0 1 1 1 0 MYND finger Ald_Xan_dh_C2 PF02738.13 KKK21105.1 - 4.5e-186 619.3 1.4 6.8e-186 618.8 1.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KKK21105.1 - 4.6e-48 162.8 0.0 8.6e-48 161.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KKK21105.1 - 6.6e-34 116.3 0.0 1.4e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KKK21105.1 - 7.2e-32 109.3 0.0 3.8e-31 107.0 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KKK21105.1 - 9.3e-29 99.1 0.0 1.9e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KKK21105.1 - 2.6e-08 33.4 0.1 2.6e-08 33.4 0.1 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Reprolysin_5 PF13688.1 KKK21106.1 - 4.9e-45 153.8 15.5 4.9e-45 153.8 10.8 3.4 2 2 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KKK21106.1 - 2.4e-37 128.6 7.2 2.4e-37 128.6 5.0 2.1 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KKK21106.1 - 4.6e-34 117.7 15.0 9e-34 116.8 5.4 2.6 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KKK21106.1 - 2.9e-19 69.0 33.5 2.9e-19 69.0 23.2 5.1 3 2 2 5 5 5 1 Disintegrin Reprolysin_3 PF13582.1 KKK21106.1 - 5e-13 49.6 0.8 2.4e-12 47.4 0.5 2.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 KKK21106.1 - 0.00036 20.3 0.1 0.0012 18.5 0.0 1.9 1 0 0 1 1 1 1 Reprolysin family propeptide EF-hand_1 PF00036.27 KKK21107.1 - 2.1e-15 54.7 1.0 5.8e-05 22.1 0.0 3.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KKK21107.1 - 4e-15 55.7 0.3 1.2e-08 34.9 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KKK21107.1 - 6.3e-14 50.5 4.4 7.1e-06 25.4 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KKK21107.1 - 2.6e-11 42.9 0.7 1.1e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KKK21107.1 - 0.052 12.9 7.0 0.67 9.3 0.1 3.2 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.2 KKK21107.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3729 PF12526.3 KKK21107.1 - 2.7 9.3 7.9 1.4 10.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) MgsA_C PF12002.3 KKK21108.1 - 6e-59 198.5 0.3 1.7e-58 197.0 0.1 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KKK21108.1 - 5.6e-15 55.7 0.0 1.3e-14 54.5 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KKK21108.1 - 1.1e-11 44.2 0.0 4.8e-11 42.1 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK21108.1 - 6.6e-06 25.7 0.0 2.1e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KKK21108.1 - 8.1e-06 25.1 0.1 0.065 12.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK21108.1 - 1e-05 25.2 0.0 0.00011 21.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK21108.1 - 1.3e-05 24.7 0.0 7.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KKK21108.1 - 0.00015 21.3 0.0 0.0075 15.7 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 KKK21108.1 - 0.00066 19.8 0.1 0.0031 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK21108.1 - 0.0031 17.4 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KKK21108.1 - 0.0042 17.1 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 KKK21108.1 - 0.0043 15.8 0.0 0.036 12.7 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_16 PF13191.1 KKK21108.1 - 0.0051 16.8 0.1 0.22 11.5 0.0 2.9 2 1 1 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 KKK21108.1 - 0.007 17.1 0.0 0.02 15.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KKK21108.1 - 0.0077 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KKK21108.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ResIII PF04851.10 KKK21108.1 - 0.021 14.6 0.2 1.9 8.3 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KKK21108.1 - 0.023 14.6 0.1 0.056 13.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF927 PF06048.6 KKK21108.1 - 0.056 12.6 0.1 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF927) AAA_10 PF12846.2 KKK21108.1 - 0.06 12.7 0.5 16 4.7 0.0 3.0 2 1 0 2 2 2 0 AAA-like domain SKI PF01202.17 KKK21108.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase RNA_helicase PF00910.17 KKK21108.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CPT PF07931.7 KKK21108.1 - 0.11 12.0 0.1 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 KKK21108.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Aminotran_1_2 PF00155.16 KKK21109.1 - 1.6e-59 201.6 0.0 1.3e-58 198.7 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KKK21109.1 - 0.00018 19.9 0.0 0.00029 19.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KKK21109.1 - 0.00053 19.2 0.0 0.0008 18.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KKK21109.1 - 0.00071 18.7 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KKK21109.1 - 0.019 13.6 0.0 0.046 12.4 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V IMS PF00817.15 KKK21110.1 - 4.1e-37 127.2 0.0 1.4e-36 125.5 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KKK21110.1 - 3.5e-10 39.8 0.2 3.7e-09 36.5 0.1 2.4 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KKK21110.1 - 0.0007 19.4 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Pkinase PF00069.20 KKK21116.1 - 3.5e-22 78.8 0.0 8.4e-22 77.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21116.1 - 1.5e-08 34.0 0.0 9.5e-05 21.5 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KKK21116.1 - 0.00043 19.4 0.0 0.00074 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK21116.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KKK21116.1 - 0.0018 17.2 0.0 0.44 9.4 0.0 2.9 3 0 0 3 3 3 1 Kinase-like WaaY PF06176.6 KKK21116.1 - 0.042 13.0 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) HATPase_c PF02518.21 KKK21117.1 - 1.1e-24 86.2 0.0 8.9e-24 83.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK21117.1 - 5.3e-23 81.1 0.0 1.2e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KKK21117.1 - 1.8e-22 79.6 0.0 3.3e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 KKK21117.1 - 1.3e-18 66.7 0.1 2.9e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KKK21117.1 - 1.6e-14 53.6 0.0 4.1e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KKK21117.1 - 1.9e-09 37.5 0.0 9.8e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_7 PF12860.2 KKK21117.1 - 0.096 12.7 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 PAS fold Oxysterol_BP PF01237.13 KKK21123.1 - 5.5e-130 432.9 0.0 1.8e-129 431.2 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.6 KKK21123.1 - 4.6e-38 129.9 1.2 1.1e-37 128.7 0.8 1.7 1 0 0 1 1 1 1 ATP12 chaperone protein Ank_2 PF12796.2 KKK21123.1 - 1.1e-16 60.9 0.0 3.5e-11 43.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK21123.1 - 3.3e-15 55.7 0.2 1.9e-10 40.6 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KKK21123.1 - 4.6e-14 51.4 0.0 0.00016 21.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KKK21123.1 - 7.2e-12 45.4 0.0 5.5e-06 26.7 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK21123.1 - 3.9e-11 42.0 0.0 0.0032 17.5 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 KKK21123.1 - 5.3e-11 42.6 0.2 1.3e-10 41.3 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KKK21123.1 - 6.2e-07 29.4 0.9 1.7e-06 27.9 0.6 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain ArgK PF03308.11 KKK21123.1 - 1.7 7.3 5.4 2.7 6.7 0.5 2.9 3 0 0 3 3 3 0 ArgK protein zf-Mss51 PF13824.1 KKK21124.1 - 7e-29 99.4 6.1 1.5e-28 98.4 4.3 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KKK21124.1 - 0.01 15.6 2.4 0.014 15.2 0.2 2.1 2 0 0 2 2 2 0 MYND finger zf-HIT PF04438.11 KKK21124.1 - 0.24 11.0 2.7 1.5 8.4 0.2 2.4 2 0 0 2 2 2 0 HIT zinc finger Glyco_tranf_2_3 PF13641.1 KKK21125.1 - 1.2e-27 97.2 0.2 1.4e-27 97.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KKK21125.1 - 1.9e-09 37.0 0.1 1.5e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KKK21125.1 - 1.3e-08 34.6 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 adh_short PF00106.20 KKK21127.1 - 6.1e-18 65.2 0.0 8.2e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK21127.1 - 1.1e-08 34.8 0.0 1.5e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK21127.1 - 3e-06 27.1 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KKK21127.1 - 0.02 14.3 0.2 0.05 13.0 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ank_2 PF12796.2 KKK21128.1 - 5.1e-32 110.0 0.4 5.4e-15 55.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KKK21128.1 - 7.2e-28 94.9 0.3 2.5e-07 30.1 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KKK21128.1 - 1.3e-25 89.2 1.1 2.1e-10 40.7 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK21128.1 - 5.8e-19 67.6 0.5 2.2e-09 37.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK21128.1 - 1.1e-18 65.4 0.3 0.00077 19.4 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat bZIP_1 PF00170.16 KKK21128.1 - 3.9e-06 26.7 2.8 6.1e-06 26.0 2.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK21128.1 - 5e-05 23.0 0.7 7.7e-05 22.4 0.5 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK21128.1 - 0.087 13.1 3.9 0.15 12.3 2.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF829 PF05705.9 KKK21129.1 - 2.3e-46 158.4 0.0 3.3e-32 112.1 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) NmrA PF05368.8 KKK21130.1 - 3.5e-14 52.6 0.0 8.5e-14 51.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK21130.1 - 8.5e-07 29.1 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK21130.1 - 0.01 14.5 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KKK21130.1 - 0.034 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Lipase_GDSL PF00657.17 KKK21131.1 - 2.4e-20 73.3 0.0 2.9e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KKK21131.1 - 3.6e-19 69.5 0.0 4.7e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AP_endonuc_2 PF01261.19 KKK21131.1 - 0.055 12.7 0.0 1 8.6 0.0 2.0 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel 4HBT_3 PF13622.1 KKK21132.1 - 3e-55 187.7 0.6 3.4e-55 187.5 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KKK21132.1 - 0.06 13.4 0.1 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Thioesterase superfamily FAD_binding_4 PF01565.18 KKK21133.1 - 8.8e-18 64.1 0.8 1.5e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KKK21133.1 - 4.6e-09 36.0 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like YiaAB PF05360.9 KKK21134.1 - 0.083 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 yiaA/B two helix domain FrhB_FdhB_C PF04432.8 KKK21134.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Fungal_trans PF04082.13 KKK21134.1 - 0.13 11.0 4.7 0.036 12.9 0.6 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain Pyr_redox_2 PF07992.9 KKK21135.1 - 1.3e-14 54.5 1.2 9.9e-14 51.6 0.8 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK21135.1 - 2.3e-14 53.5 0.5 2.9e-08 34.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK21135.1 - 1.9e-09 37.8 2.5 0.076 13.0 0.0 4.0 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK21135.1 - 2.8e-08 33.0 5.4 0.059 12.2 0.1 3.6 2 1 2 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK21135.1 - 1.6e-05 24.7 1.3 0.32 10.7 0.0 4.0 4 0 0 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.13 KKK21135.1 - 2.6e-05 24.2 1.1 0.2 11.6 0.0 3.5 4 0 0 4 4 4 2 TrkA-N domain K_oxygenase PF13434.1 KKK21135.1 - 0.0003 19.8 0.1 0.6 8.9 0.0 2.5 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KKK21135.1 - 0.00039 19.4 1.0 0.16 10.8 0.0 3.0 4 0 0 4 4 4 2 Lycopene cyclase protein NAD_binding_7 PF13241.1 KKK21135.1 - 0.014 15.6 0.1 3.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KKK21135.1 - 0.021 14.8 0.0 0.39 10.7 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK21135.1 - 0.12 11.4 2.8 5.8 5.9 0.1 2.5 3 0 0 3 3 3 0 Thi4 family Laminin_II PF06009.7 KKK21137.1 - 0.007 16.1 0.5 0.0085 15.8 0.3 1.2 1 0 0 1 1 1 1 Laminin Domain II CAF-1_p150 PF11600.3 KKK21137.1 - 0.0085 15.4 10.3 0.01 15.2 7.1 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MutS_IV PF05190.13 KKK21137.1 - 0.043 13.9 1.0 0.069 13.3 0.7 1.3 1 0 0 1 1 1 0 MutS family domain IV ATP-synt_B PF00430.13 KKK21137.1 - 0.2 11.4 7.9 0.29 10.9 5.5 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Phage_1_1 PF08200.6 KKK21137.1 - 0.25 11.5 2.6 0.24 11.6 0.5 2.0 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein SR-25 PF10500.4 KKK21137.1 - 8.4 5.8 22.6 17 4.8 15.6 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein ADP_ribosyl_GH PF03747.9 KKK21138.1 - 1.4e-55 189.0 0.0 1.7e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF3725 PF12523.3 KKK21138.1 - 0.074 13.1 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) EFhand_Ca_insen PF08726.5 KKK21138.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Rick_17kDa_Anti PF05433.10 KKK21138.1 - 0.61 9.7 2.8 13 5.5 0.3 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain KxDL PF10241.4 KKK21146.1 - 4.3e-34 116.2 0.7 5.4e-34 115.9 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein MFS_1 PF07690.11 KKK21147.1 - 7.3e-40 136.7 36.8 1.4e-38 132.5 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK21147.1 - 3.1e-12 45.8 12.7 3.1e-12 45.8 8.8 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KKK21147.1 - 6e-08 31.3 5.5 9.5e-08 30.6 3.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BCAS2 PF05700.6 KKK21148.1 - 9.3e-58 195.2 0.7 1e-57 195.1 0.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 KKK21148.1 - 0.82 9.4 7.8 2.5 7.8 5.1 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CRC_subunit PF08624.5 KKK21149.1 - 7.7e-55 184.6 0.2 1.1e-54 184.1 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit TLP-20 PF06088.6 KKK21149.1 - 8.8 5.9 8.1 0.9 9.1 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Snf7 PF03357.16 KKK21150.1 - 4.3e-35 120.6 22.0 4.3e-35 120.6 15.3 2.0 2 0 0 2 2 2 2 Snf7 MpPF1 PF07668.6 KKK21150.1 - 0.043 12.9 4.5 0.059 12.5 3.2 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 1 TraF_2 PF13729.1 KKK21150.1 - 0.11 11.2 2.6 0.076 11.7 0.5 1.6 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein DUF3138 PF11336.3 KKK21150.1 - 0.54 8.3 7.2 0.84 7.7 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) PglZ PF08665.7 KKK21150.1 - 1.7 8.3 8.1 0.47 10.1 2.1 2.0 1 1 1 2 2 2 0 PglZ domain EI24 PF07264.6 KKK21152.1 - 2.1e-07 30.6 16.1 3.9e-07 29.7 11.2 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2583 PF10762.4 KKK21152.1 - 1.4 9.0 3.8 4.9 7.3 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) DUF4231 PF14015.1 KKK21152.1 - 5.8 6.9 6.5 4.1 7.4 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Zn_clus PF00172.13 KKK21153.1 - 1.3e-08 34.5 10.3 2.7e-08 33.5 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK21153.1 - 0.067 12.0 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ceramidase_alk PF04734.8 KKK21154.1 - 2.9e-277 921.0 0.0 3.3e-277 920.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Mito_carr PF00153.22 KKK21155.1 - 1.1e-58 194.8 0.1 7.6e-19 67.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_2 PF08023.7 KKK21155.1 - 0.13 12.5 0.5 0.4 11.0 0.3 1.8 1 0 0 1 1 1 0 Frog antimicrobial peptide GTP_EFTU PF00009.22 KKK21156.1 - 3.3e-34 117.9 2.2 3.3e-34 117.9 1.5 2.3 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KKK21156.1 - 2.4e-24 85.2 0.0 5.4e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KKK21156.1 - 2e-12 47.0 0.9 5.8e-07 29.5 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 KKK21156.1 - 3e-10 39.6 0.0 9e-10 38.0 0.0 1.9 2 0 0 2 2 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 KKK21156.1 - 8.7e-07 28.9 0.0 2.3e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK21156.1 - 0.00037 20.9 0.1 0.00089 19.7 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK21156.1 - 0.0026 17.0 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KKK21156.1 - 0.0064 15.7 0.0 0.0064 15.7 0.0 2.2 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KKK21156.1 - 0.0088 15.5 0.1 0.025 14.0 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DZR PF12773.2 KKK21156.1 - 0.013 15.2 2.1 0.025 14.3 1.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Dynamin_N PF00350.18 KKK21156.1 - 0.15 11.8 5.0 17 5.2 0.0 4.1 3 1 1 4 4 4 0 Dynamin family MIF4G PF02854.14 KKK21156.1 - 0.43 9.9 1.0 0.8 9.0 0.7 1.4 1 0 0 1 1 1 0 MIF4G domain Zn_clus PF00172.13 KKK21158.1 - 0.00099 18.9 6.0 0.0015 18.3 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 KKK21158.1 - 0.088 12.5 6.8 0.28 10.9 4.7 1.9 1 0 0 1 1 1 0 AT hook motif Glyco_transf_20 PF00982.16 KKK21161.1 - 1.2e-199 663.6 0.0 1.4e-199 663.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KKK21161.1 - 0.0054 16.2 0.3 0.019 14.4 0.1 1.9 2 1 0 2 2 2 1 Starch synthase catalytic domain Lactamase_B PF00753.22 KKK21162.1 - 8.2e-23 81.0 4.0 1.2e-22 80.5 2.5 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK21162.1 - 6e-05 22.6 2.1 7.8e-05 22.2 1.5 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KKK21162.1 - 0.0094 15.6 0.7 0.032 13.9 0.5 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HEAT PF02985.17 KKK21163.1 - 0.00012 21.8 0.1 1.1 9.5 0.1 4.6 4 0 0 4 4 4 1 HEAT repeat IncA PF04156.9 KKK21163.1 - 0.00028 20.5 1.4 0.00028 20.5 1.0 2.0 2 0 0 2 2 2 1 IncA protein CLASP_N PF12348.3 KKK21163.1 - 0.001 18.4 0.4 0.026 13.8 0.2 2.8 2 1 1 3 3 3 1 CLASP N terminal APG6 PF04111.7 KKK21163.1 - 0.0026 16.8 10.2 0.0026 16.8 7.0 2.2 3 0 0 3 3 3 1 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KKK21163.1 - 0.0041 16.8 2.3 0.0041 16.8 1.6 2.8 4 0 0 4 4 3 1 TPR/MLP1/MLP2-like protein Adaptin_N PF01602.15 KKK21163.1 - 0.0056 15.0 1.3 0.12 10.6 0.9 2.6 1 1 0 1 1 1 1 Adaptin N terminal region MMS19_N PF14500.1 KKK21163.1 - 0.027 13.7 0.6 0.79 8.9 0.3 2.8 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II FTCD_N PF07837.7 KKK21163.1 - 0.054 13.0 0.5 0.91 9.0 0.0 2.8 3 0 0 3 3 3 0 Formiminotransferase domain, N-terminal subdomain DUF4471 PF14740.1 KKK21163.1 - 0.058 12.6 0.2 0.15 11.2 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) Cnd1 PF12717.2 KKK21163.1 - 0.089 12.6 0.2 1.6 8.5 0.1 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF972 PF06156.8 KKK21163.1 - 1 9.7 4.8 4.2 7.7 3.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ADIP PF11559.3 KKK21163.1 - 3.8 7.3 14.9 12 5.7 10.3 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tropomyosin PF00261.15 KKK21163.1 - 5.2 6.0 18.6 0.19 10.7 8.6 1.7 2 0 0 2 2 2 0 Tropomyosin Spc7 PF08317.6 KKK21163.1 - 5.5 5.5 11.6 0.61 8.6 4.8 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.9 KKK21163.1 - 8 6.3 14.5 25 4.7 6.4 2.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ribosomal_S17 PF00366.15 KKK21164.1 - 0.008 16.1 0.4 0.014 15.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 PDDEXK_1 PF12705.2 KKK21164.1 - 0.025 13.9 0.1 3.8 6.8 0.7 2.0 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily Mito_carr PF00153.22 KKK21165.1 - 2.8e-50 167.9 0.6 3.9e-22 77.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Vac14_Fig4_bd PF11916.3 KKK21166.1 - 1.1e-82 275.6 7.9 1.1e-82 275.6 5.5 1.6 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding SNF2_N PF00176.18 KKK21166.1 - 1.9e-64 217.3 0.0 2.9e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KKK21166.1 - 4.5e-63 212.5 2.8 4.6e-62 209.2 1.5 2.4 2 0 0 2 2 2 1 Rad54 N terminal Vac14_Fab1_bd PF12755.2 KKK21166.1 - 3.2e-44 149.2 0.1 2.8e-42 143.0 0.0 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Helicase_C PF00271.26 KKK21166.1 - 1.2e-11 44.3 0.0 3.1e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.1 KKK21166.1 - 6.4e-08 32.8 0.3 0.0029 18.0 0.0 4.3 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KKK21166.1 - 1.4e-07 31.0 0.8 0.00045 20.0 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 KKK21166.1 - 3.7e-06 27.1 0.1 0.018 15.3 0.0 4.2 3 1 0 3 3 3 1 HEAT repeats HDA2-3 PF11496.3 KKK21166.1 - 0.00025 19.9 0.0 0.00081 18.2 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KKK21166.1 - 0.027 14.3 0.0 0.19 11.5 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Aconitase PF00330.15 KKK21167.1 - 3.8e-174 579.5 0.0 9.4e-174 578.2 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KKK21167.1 - 1.9e-45 154.1 0.0 3.5e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 KKK21168.1 - 6.1e-09 35.7 3.6 1e-08 35.0 2.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KKK21168.1 - 0.068 13.1 0.8 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Ribosomal_L2 PF00181.18 KKK21168.1 - 0.072 13.0 0.5 0.98 9.4 0.0 2.1 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain zf-met PF12874.2 KKK21168.1 - 0.081 13.1 1.5 0.16 12.2 1.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KKK21168.1 - 0.084 12.9 0.3 0.13 12.4 0.2 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KKK21168.1 - 0.087 12.3 0.4 0.17 11.4 0.3 1.5 1 0 0 1 1 1 0 U1 zinc finger ATP-synt_10 PF05176.9 KKK21169.1 - 9.3e-95 316.6 0.0 1.3e-94 316.2 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein Stn1 PF10451.4 KKK21181.1 - 7e-08 31.6 0.0 4.3e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 DnaJ PF00226.26 KKK21182.1 - 5.8e-24 83.6 2.4 5.8e-24 83.6 1.7 2.0 2 0 0 2 2 2 1 DnaJ domain DltD_M PF04918.7 KKK21182.1 - 3.5 7.8 10.3 0.94 9.6 4.5 1.8 2 0 0 2 2 2 0 DltD central region Stc1 PF12898.2 KKK21184.1 - 3.7e-22 78.1 4.3 6.3e-22 77.4 3.0 1.3 1 0 0 1 1 1 1 Stc1 domain RE_LlaMI PF09562.5 KKK21184.1 - 0.002 17.3 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 LlaMI restriction endonuclease FAM60A PF15396.1 KKK21184.1 - 0.037 13.7 1.2 0.19 11.4 1.3 1.7 2 0 0 2 2 2 0 Protein Family FAM60A zf-RING_5 PF14634.1 KKK21184.1 - 0.39 10.4 4.2 0.33 10.7 0.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Amidase PF01425.16 KKK21185.1 - 4.8e-64 216.8 0.0 7.5e-54 183.2 0.0 2.2 1 1 1 2 2 2 2 Amidase DUF2422 PF10337.4 KKK21203.1 - 1.6e-98 330.5 0.3 1.6e-98 330.5 0.2 4.1 4 1 0 4 4 4 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KKK21203.1 - 3.5e-18 65.7 12.4 3.5e-18 65.7 8.6 3.2 2 2 1 3 3 3 1 Fusaric acid resistance protein-like MFS_1 PF07690.11 KKK21203.1 - 1.2e-15 57.1 14.0 1.2e-15 57.1 9.7 3.6 3 1 0 3 3 3 1 Major Facilitator Superfamily DUF2421 PF10334.4 KKK21203.1 - 1.9e-14 53.8 0.0 1.2e-13 51.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 KKK21203.1 - 0.00024 20.9 7.1 0.00024 20.9 4.9 3.9 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF939) ALMT PF11744.3 KKK21203.1 - 0.32 9.5 12.5 1.5 7.4 6.3 2.8 2 1 0 2 2 2 0 Aluminium activated malate transporter TRI12 PF06609.8 KKK21204.1 - 0.00082 17.6 3.4 0.001 17.3 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 7tm_7 PF08395.7 KKK21204.1 - 0.086 11.8 3.3 0.15 11.0 2.0 1.5 2 0 0 2 2 2 0 7tm Chemosensory receptor Fungal_trans PF04082.13 KKK21220.1 - 4.1e-20 71.7 0.0 7.7e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21220.1 - 0.00076 19.3 5.9 0.0014 18.4 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb4 PF03874.11 KKK21221.1 - 2.8e-27 95.0 2.3 3.4e-27 94.7 1.6 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Met_10 PF02475.11 KKK21222.1 - 5.2e-61 205.7 0.0 8.2e-61 205.0 0.0 1.3 1 1 0 1 1 1 1 Met-10+ like-protein Proteasome PF00227.21 KKK21223.1 - 6.2e-49 165.8 0.1 1e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit DUF2373 PF10180.4 KKK21223.1 - 1.1e-20 72.8 0.1 2.1e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF3650 PF12368.3 KKK21223.1 - 1.1 8.7 3.6 0.48 9.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) RVT_2 PF07727.9 KKK21224.1 - 8.8e-37 126.3 0.2 3.7e-35 121.0 0.1 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_3 PF14244.1 KKK21224.1 - 3.8e-06 26.5 0.0 9.5e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type SIS PF01380.17 KKK21225.1 - 6.6e-56 187.5 0.0 3.2e-30 104.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KKK21225.1 - 1.7e-28 99.3 0.0 2.9e-19 68.9 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KKK21225.1 - 9.6e-20 70.9 0.0 2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KKK21225.1 - 6e-12 45.3 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KKK21225.1 - 2e-08 33.2 0.0 4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KKK21225.1 - 0.07 12.8 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 SIS domain DMRL_synthase PF00885.14 KKK21226.1 - 2.6e-45 153.6 0.0 4.2e-26 91.3 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase LAT PF15234.1 KKK21227.1 - 2.1 7.7 8.3 0.28 10.6 2.5 1.9 2 1 0 2 2 2 0 Linker for activation of T-cells Rad4 PF03835.10 KKK21228.1 - 3.1e-36 123.9 0.4 9.4e-36 122.3 0.3 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KKK21228.1 - 4.2e-29 100.0 0.1 7.9e-29 99.1 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 KKK21228.1 - 7.9e-17 61.3 0.7 7.9e-17 61.3 0.5 2.8 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 KKK21228.1 - 2.1e-16 59.1 0.0 4.7e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 KKK21228.1 - 0.0044 17.2 0.0 0.26 11.5 0.0 2.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF3420 PF11900.3 KKK21228.1 - 0.081 13.0 0.8 0.26 11.4 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) CoA_binding_2 PF13380.1 KKK21229.1 - 6.2e-26 90.8 0.0 7.9e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain HD_3 PF13023.1 KKK21230.1 - 4.1e-45 153.4 0.1 5.3e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 KKK21230.1 - 0.12 12.4 0.1 0.33 10.9 0.1 1.9 1 1 0 1 1 1 0 HD domain HIT PF01230.18 KKK21231.1 - 4.7e-18 65.5 0.0 6.7e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KKK21231.1 - 3.5e-05 23.9 0.0 5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HAUS6_N PF14661.1 KKK21232.1 - 8.5e-48 162.8 0.1 1.3e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DHC_N1 PF08385.7 KKK21233.1 - 3.1e-189 630.1 12.6 3.1e-189 630.1 8.7 4.4 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KKK21233.1 - 1.4e-130 435.4 16.6 3.6e-130 434.1 5.1 3.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KKK21233.1 - 6.8e-80 267.8 0.0 2.3e-79 266.1 0.0 2.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KKK21233.1 - 1.2e-42 145.7 0.2 1.7e-41 141.9 0.2 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 KKK21233.1 - 1.4e-32 112.3 0.0 4.9e-11 42.5 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KKK21233.1 - 3.9e-19 68.7 0.0 1.8e-18 66.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 KKK21233.1 - 4.6e-16 59.2 0.0 6.4e-05 23.1 0.0 5.5 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK21233.1 - 7.3e-16 58.5 0.1 0.0072 16.4 0.0 6.4 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.1 KKK21233.1 - 3.1e-11 43.7 0.4 0.021 15.1 0.0 5.7 6 0 0 6 6 5 2 AAA domain AAA_33 PF13671.1 KKK21233.1 - 5.9e-11 42.4 0.2 0.23 11.3 0.0 5.7 5 0 0 5 5 4 3 AAA domain AAA_17 PF13207.1 KKK21233.1 - 6.5e-11 43.1 0.1 0.029 15.1 0.0 6.3 5 0 0 5 5 5 2 AAA domain T2SE PF00437.15 KKK21233.1 - 2.6e-08 33.1 0.0 0.012 14.5 0.0 4.0 4 0 0 4 4 4 2 Type II/IV secretion system protein ABC_tran PF00005.22 KKK21233.1 - 8.3e-07 29.3 0.3 0.32 11.2 0.0 5.4 4 0 0 4 4 4 2 ABC transporter AAA_14 PF13173.1 KKK21233.1 - 1.9e-06 27.7 0.0 0.19 11.6 0.0 5.1 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.1 KKK21233.1 - 2.1e-06 27.1 0.0 1 8.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.1 KKK21233.1 - 9.5e-06 25.2 0.1 0.31 10.8 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain Zeta_toxin PF06414.7 KKK21233.1 - 3.4e-05 23.0 0.0 0.34 9.9 0.0 4.0 3 0 0 3 3 3 2 Zeta toxin Mg_chelatase PF01078.16 KKK21233.1 - 0.00034 19.8 4.2 0.32 10.1 0.0 3.8 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KKK21233.1 - 0.00035 19.7 0.0 3.1 6.9 0.0 3.8 3 0 0 3 3 3 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KKK21233.1 - 0.00047 19.6 0.4 12 5.2 0.0 4.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KKK21233.1 - 0.00055 19.9 23.0 0.11 12.4 0.1 8.8 7 3 2 10 10 10 1 AAA ATPase domain IstB_IS21 PF01695.12 KKK21233.1 - 0.00078 18.9 0.4 0.19 11.1 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KKK21233.1 - 0.0011 19.1 0.2 12 6.1 0.0 5.1 5 0 0 5 5 5 0 RNA helicase MobB PF03205.9 KKK21233.1 - 0.0038 16.9 0.3 8.5 6.0 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KKK21233.1 - 0.0045 16.4 0.4 0.56 9.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain PduV-EutP PF10662.4 KKK21233.1 - 0.054 12.9 1.5 5.1 6.5 0.1 3.7 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KKK21233.1 - 0.11 11.9 7.4 9 5.6 0.2 4.6 4 0 0 4 4 4 0 AAA-like domain Dynein_heavy PF03028.10 KKK21234.1 - 5.4e-109 365.2 0.0 1e-108 364.2 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 KKK21234.1 - 9.2e-44 148.9 1.2 1.1e-43 148.7 0.0 1.7 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 KKK21234.1 - 1.6e-25 89.6 0.3 2.9e-25 88.7 0.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor BRE1 PF08647.6 KKK21234.1 - 0.00091 19.1 2.3 0.00091 19.1 1.6 2.3 2 0 0 2 2 2 1 BRE1 E3 ubiquitin ligase 3-alpha PF03475.9 KKK21234.1 - 0.0018 17.9 0.2 0.005 16.5 0.1 1.8 1 0 0 1 1 1 1 3-alpha domain DUF3867 PF12983.2 KKK21234.1 - 0.0042 17.0 0.4 0.0042 17.0 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3867) Hemerythrin PF01814.18 KKK21234.1 - 0.016 15.3 1.4 0.66 10.1 0.2 2.7 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain THOC7 PF05615.8 KKK21234.1 - 0.02 15.1 7.0 0.24 11.6 1.0 3.4 2 1 0 2 2 2 0 Tho complex subunit 7 zf-C4H2 PF10146.4 KKK21234.1 - 0.046 13.7 2.1 0.08 12.9 0.1 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein AAA_23 PF13476.1 KKK21234.1 - 0.048 13.9 4.4 0.22 11.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain DUF342 PF03961.8 KKK21234.1 - 0.14 10.5 7.3 1.7 6.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TPR_MLP1_2 PF07926.7 KKK21234.1 - 0.35 10.6 10.1 0.52 10.0 3.3 3.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KKK21234.1 - 0.43 9.7 6.4 1.1 8.4 0.3 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 KKK21234.1 - 0.44 10.4 3.3 2.1 8.3 0.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF724 PF05266.9 KKK21234.1 - 0.97 9.0 6.9 0.17 11.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6 PF04111.7 KKK21234.1 - 1.2 8.1 13.7 0.072 12.1 2.1 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 KKK21234.1 - 1.2 9.0 10.3 0.87 9.4 1.7 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 KKK21234.1 - 1.3 9.3 10.7 1.1 9.6 0.9 4.4 3 1 0 3 3 3 0 Protein of unknown function (DUF904) ERM PF00769.14 KKK21234.1 - 2 7.8 10.0 0.094 12.2 2.5 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF972 PF06156.8 KKK21234.1 - 8.2 6.8 8.4 6.2 7.2 1.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Ribonuclease_3 PF00636.21 KKK21235.1 - 2e-42 144.2 0.0 4.8e-20 72.0 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KKK21235.1 - 1.9e-23 82.7 0.0 1.2e-11 44.6 0.0 3.9 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 KKK21235.1 - 1.3e-22 79.4 0.0 3e-21 74.9 0.0 2.8 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 KKK21235.1 - 5e-14 51.9 0.0 1.3e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK21235.1 - 2.7e-11 43.6 0.1 7.6e-11 42.1 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KKK21235.1 - 2.6e-09 36.8 0.0 1.1e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase dsrm PF00035.20 KKK21235.1 - 0.00028 21.4 0.0 0.85 10.2 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DUF2075 PF09848.4 KKK21235.1 - 0.0085 15.1 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Lon_C PF05362.8 KKK21236.1 - 1.6e-69 233.2 0.3 1.1e-68 230.6 0.1 2.2 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KKK21236.1 - 8.1e-28 97.5 0.8 1.3e-27 96.8 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KKK21236.1 - 2e-23 83.0 0.0 1.2e-22 80.4 0.0 2.4 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KKK21236.1 - 3.6e-08 32.9 0.1 3e-07 29.9 0.0 2.3 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KKK21236.1 - 6.3e-08 32.4 0.0 2.1e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK21236.1 - 2.6e-06 27.5 2.0 6.8e-06 26.1 0.0 2.7 3 1 1 4 4 3 1 AAA ATPase domain AAA_17 PF13207.1 KKK21236.1 - 3.6e-05 24.5 0.0 0.00017 22.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KKK21236.1 - 5.1e-05 22.9 0.1 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 KKK21236.1 - 5.8e-05 22.7 0.0 0.00018 21.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KKK21236.1 - 0.00016 20.7 0.1 0.0018 17.3 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KKK21236.1 - 0.00033 19.4 0.1 0.0028 16.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 KKK21236.1 - 0.0006 19.7 0.0 0.0022 17.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KKK21236.1 - 0.0014 18.7 0.1 0.014 15.5 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.1 KKK21236.1 - 0.0018 18.1 0.0 0.0067 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK21236.1 - 0.0021 17.2 0.0 0.0049 15.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 KKK21236.1 - 0.0048 16.3 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KKK21236.1 - 0.0091 15.8 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KKK21236.1 - 0.015 14.6 0.0 0.05 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KKK21236.1 - 0.021 14.4 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KKK21236.1 - 0.025 14.1 0.1 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KKK21236.1 - 0.036 13.2 0.1 0.099 11.7 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KKK21236.1 - 0.042 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK21236.1 - 0.052 13.2 0.1 0.19 11.3 0.0 2.0 2 0 0 2 2 1 0 NACHT domain AAA_18 PF13238.1 KKK21236.1 - 0.052 13.8 1.5 0.076 13.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 KKK21236.1 - 0.062 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 KKK21236.1 - 0.072 12.6 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KKK21236.1 - 0.074 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CCDC-167 PF15188.1 KKK21236.1 - 0.13 12.2 5.0 0.78 9.7 1.1 3.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 AAA_23 PF13476.1 KKK21236.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.9 2 1 0 2 2 1 0 AAA domain AAA_PrkA PF08298.6 KKK21236.1 - 0.19 10.4 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain Porphobil_deam PF01379.15 KKK21237.1 - 1.2e-76 256.3 0.0 1.5e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KKK21237.1 - 1.6e-17 63.3 0.0 2.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain PCP_red PF08369.5 KKK21238.1 - 0.02 14.7 0.4 0.034 14.0 0.3 1.4 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Svf1 PF08622.5 KKK21239.1 - 5.3e-118 393.7 0.0 5.9e-118 393.5 0.0 1.0 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 KKK21239.1 - 0.011 15.0 0.1 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) TAP42 PF04177.7 KKK21240.1 - 5.3e-99 331.3 15.0 1.2e-98 330.1 10.4 1.5 1 1 0 1 1 1 1 TAP42-like family RIO1 PF01163.17 KKK21241.1 - 8.9e-40 136.0 0.6 6e-28 97.4 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 KKK21241.1 - 2e-31 107.9 0.0 5.5e-31 106.4 0.0 1.8 1 0 0 1 1 1 1 Rio2, N-terminal PC_rep PF01851.17 KKK21241.1 - 2e-15 56.0 13.6 0.00048 20.2 0.1 7.8 8 0 0 8 8 8 3 Proteasome/cyclosome repeat APH PF01636.18 KKK21241.1 - 5.1e-06 26.3 0.0 0.015 15.0 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KKK21241.1 - 3.6e-05 22.9 0.1 0.00052 19.1 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L23 PF00276.15 KKK21242.1 - 1.2e-14 54.0 0.0 1.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 DNA_mis_repair PF01119.14 KKK21243.1 - 6.4e-32 109.5 0.2 1.1e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KKK21243.1 - 1.6e-14 53.7 0.0 4.6e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KKK21243.1 - 1.8e-12 46.9 0.0 1.2e-10 41.0 0.0 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PNRC PF15365.1 KKK21243.1 - 0.0017 18.3 0.5 0.0051 16.7 0.3 1.8 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator P-II PF00543.17 KKK21246.1 - 0.058 13.8 0.0 0.073 13.5 0.0 1.2 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II YpjP PF14005.1 KKK21246.1 - 0.098 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 YpjP-like protein DUF3745 PF12560.3 KKK21246.1 - 0.12 12.1 0.5 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3745) TGS PF02824.16 KKK21247.1 - 1.1e-20 73.2 0.1 1.9e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KKK21247.1 - 2.1e-19 69.5 0.1 1.1e-18 67.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK21247.1 - 6.8e-12 44.9 0.0 1.1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KKK21247.1 - 7e-05 22.7 0.2 0.064 13.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KKK21247.1 - 0.0015 18.9 0.0 0.0048 17.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 KKK21247.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 KKK21247.1 - 0.027 13.2 0.1 0.058 12.1 0.1 1.6 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 KKK21247.1 - 0.037 12.8 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 KKK21247.1 - 0.23 12.2 1.0 1.6 9.6 0.7 2.3 1 1 0 1 1 1 0 AAA domain CPSase_sm_chain PF00988.17 KKK21248.1 - 5.5e-46 155.2 0.0 9.6e-46 154.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KKK21248.1 - 6.9e-46 156.1 0.0 9.5e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KKK21248.1 - 4.5e-06 26.2 0.1 0.00019 20.9 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 DUF1250 PF06855.7 KKK21248.1 - 0.14 11.6 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) Zn_clus PF00172.13 KKK21249.1 - 5.9e-09 35.6 9.6 1e-08 34.9 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK21249.1 - 1.4e-08 33.9 0.0 2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 KKK21251.1 - 9.3e-48 162.1 20.0 9.3e-48 162.1 13.8 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KKK21251.1 - 5.3e-38 130.4 0.0 2.7e-18 66.5 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KKK21251.1 - 2.5e-34 117.0 0.7 9e-34 115.2 0.0 2.1 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.1 KKK21251.1 - 7.8e-24 83.5 0.0 1.3e-22 79.6 0.1 2.4 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KKK21251.1 - 2.6e-07 30.2 0.1 0.00022 20.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KKK21251.1 - 1.1e-06 27.9 0.0 0.00012 21.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK21251.1 - 0.0002 21.4 1.1 0.0031 17.5 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KKK21251.1 - 0.00032 20.6 1.1 0.038 13.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KKK21251.1 - 0.00043 19.7 1.6 0.015 14.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK21251.1 - 0.0014 18.8 0.5 0.72 10.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 KKK21251.1 - 0.0015 19.3 0.0 0.44 11.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.14 KKK21251.1 - 0.0025 17.0 0.0 0.31 10.2 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 KKK21251.1 - 0.0029 17.0 2.1 0.013 14.9 0.0 2.5 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KKK21251.1 - 0.004 17.4 0.0 0.51 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KKK21251.1 - 0.0089 16.0 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KKK21251.1 - 0.012 16.1 0.0 3.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 KKK21251.1 - 0.022 14.9 0.0 9 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KKK21251.1 - 0.035 13.5 0.3 0.43 10.0 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 KKK21251.1 - 0.039 13.5 0.8 7.7 6.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KKK21251.1 - 0.066 13.1 0.1 0.6 10.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KKK21251.1 - 0.074 12.4 3.7 15 4.9 0.0 3.6 2 1 1 3 3 3 0 AAA-like domain NACHT PF05729.7 KKK21251.1 - 0.086 12.4 5.6 2.4 7.7 0.2 3.6 4 0 0 4 4 4 0 NACHT domain Viral_helicase1 PF01443.13 KKK21251.1 - 0.11 11.9 0.0 4 6.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase LSM PF01423.17 KKK21252.1 - 5.5e-20 70.6 0.2 7.3e-20 70.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 KKK21252.1 - 0.5 10.8 8.9 1.1 9.7 6.2 1.6 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pkinase PF00069.20 KKK21253.1 - 9.7e-07 28.1 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain UBA_4 PF14555.1 KKK21254.1 - 2.8e-09 36.3 0.0 6.9e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KKK21254.1 - 8.6e-09 35.3 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF4337 PF14235.1 KKK21254.1 - 4.7 7.0 9.1 10 5.9 6.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ribosomal_S15 PF00312.17 KKK21286.1 - 1.4e-19 69.6 0.8 3.9e-19 68.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 CytochromB561_N PF09786.4 KKK21286.1 - 0.056 11.9 2.0 0.073 11.5 1.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SOBP PF15279.1 KKK21287.1 - 0.22 11.8 19.3 0.25 11.6 13.4 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein KIAA1328 PF15369.1 KKK21287.1 - 2.2 7.9 14.7 2.8 7.6 10.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 DUF2992 PF11208.3 KKK21287.1 - 2.9 7.8 10.0 2.9 7.7 6.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) Mitofilin PF09731.4 KKK21287.1 - 3.7 6.0 20.5 4.2 5.8 14.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC27 PF09507.5 KKK21287.1 - 3.7 6.6 29.2 5 6.2 20.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_S64 PF08192.6 KKK21287.1 - 3.8 5.7 12.0 4.2 5.5 8.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_S2 PF00318.15 KKK21288.1 - 1.2e-43 148.7 0.0 4.8e-23 81.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 HsbA PF12296.3 KKK21289.1 - 1e-25 90.0 10.8 1e-25 90.0 7.5 2.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A NPV_P10 PF05531.7 KKK21289.1 - 0.51 10.6 5.8 4.5 7.5 4.0 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Copper-fist PF00649.13 KKK21290.1 - 4.5e-18 64.1 0.4 4.5e-18 64.1 0.3 2.2 2 0 0 2 2 2 1 Copper fist DNA binding domain APH PF01636.18 KKK21291.1 - 1.9e-07 31.0 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK21291.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Glyco_hydro_15 PF00723.16 KKK21292.1 - 6.7e-108 361.1 0.2 6.7e-108 361.1 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KKK21292.1 - 7.7e-33 111.9 0.1 2.3e-32 110.4 0.1 1.9 1 0 0 1 1 1 1 Starch binding domain tRNA_bind PF01588.15 KKK21293.1 - 2e-21 75.6 0.0 2.1e-19 69.1 0.0 2.5 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KKK21293.1 - 4.1e-10 40.0 0.0 1.1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK21293.1 - 1.2e-05 25.0 0.0 3.7e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KKK21293.1 - 0.0041 17.0 0.0 0.0041 17.0 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain NPR3 PF03666.8 KKK21293.1 - 0.024 13.1 2.1 0.037 12.5 1.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 IDO PF01231.13 KKK21293.1 - 0.14 10.5 0.0 0.23 9.8 0.0 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase RR_TM4-6 PF06459.7 KKK21293.1 - 7.8 6.3 11.7 12 5.7 8.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 tRNA-synt_1b PF00579.20 KKK21294.1 - 7.1e-25 87.7 0.0 1.3e-24 86.8 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) FAA_hydrolase PF01557.13 KKK21295.1 - 4e-49 167.0 0.0 5.9e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3712 PF12505.3 KKK21296.1 - 1.7e-33 115.3 0.4 4e-33 114.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) AgrB PF04647.10 KKK21296.1 - 0.042 12.9 0.9 0.064 12.3 0.7 1.2 1 0 0 1 1 1 0 Accessory gene regulator B adh_short PF00106.20 KKK21297.1 - 1.1e-31 110.0 0.2 1.7e-31 109.3 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK21297.1 - 8e-19 68.3 0.0 1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK21297.1 - 9.5e-10 38.4 0.0 1.4e-09 37.8 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK21297.1 - 4.6e-06 26.2 0.0 6.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK21297.1 - 0.00012 22.1 0.3 0.01 15.8 0.1 2.5 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KKK21297.1 - 0.00092 18.9 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KKK21297.1 - 0.11 11.3 0.0 0.25 10.2 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Fungal_trans PF04082.13 KKK21298.1 - 2.4e-27 95.4 1.9 3.8e-27 94.8 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21298.1 - 1.4e-06 28.1 6.7 3e-06 27.0 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.3 KKK21299.1 - 7.9e-37 126.1 1.0 1.2e-36 125.5 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KKK21299.1 - 0.74 9.8 11.2 0.096 12.6 4.9 1.6 2 0 0 2 2 2 0 bZIP transcription factor Rad4 PF03835.10 KKK21300.1 - 8.5e-34 116.0 0.2 2.9e-33 114.2 0.0 2.1 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KKK21300.1 - 1.2e-28 98.6 0.6 3e-28 97.3 0.1 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KKK21300.1 - 7.1e-23 79.8 0.0 1.3e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KKK21300.1 - 5.5e-15 55.4 2.2 8e-15 54.9 0.1 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KKK21300.1 - 0.012 15.7 0.0 0.046 13.9 0.0 2.1 1 1 0 1 1 1 0 Transglutaminase-like superfamily Beta-lactamase PF00144.19 KKK21301.1 - 1e-44 152.9 0.2 1.4e-44 152.4 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KKK21301.1 - 1.3e-08 34.5 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Peptidase_S9 PF00326.16 KKK21302.1 - 1.3e-40 138.8 0.7 1.8e-40 138.4 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK21302.1 - 1.5e-14 54.0 1.4 3.2e-14 52.9 1.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK21302.1 - 8.1e-11 42.2 5.9 4.1e-10 39.9 4.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KKK21302.1 - 3.4e-10 39.5 0.2 3.8e-09 36.1 0.1 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KKK21302.1 - 3.8e-10 39.6 2.7 1.9e-05 24.2 0.9 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KKK21302.1 - 4.7e-07 29.7 0.1 4.3e-06 26.6 0.1 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 KKK21302.1 - 9.3e-06 25.3 1.6 5.1e-05 22.9 1.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KKK21302.1 - 1.3e-05 25.0 0.1 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein PD40 PF07676.7 KKK21302.1 - 0.00015 21.2 1.7 0.0029 17.2 0.3 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.11 KKK21302.1 - 0.00016 21.1 0.1 0.016 14.6 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF829 PF05705.9 KKK21302.1 - 0.0014 18.4 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_1 PF00561.15 KKK21302.1 - 0.004 16.7 0.2 0.3 10.6 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 KKK21302.1 - 0.0042 16.3 1.2 0.035 13.3 0.6 2.5 2 1 0 2 2 2 1 Esterase PHB depolymerase FSH1 PF03959.8 KKK21302.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.9 KKK21302.1 - 0.1 11.7 1.9 0.52 9.4 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase MFS_1 PF07690.11 KKK21304.1 - 1.5e-14 53.5 49.2 1.4e-08 33.8 18.8 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK21304.1 - 1.6e-08 33.2 21.1 4.7e-07 28.3 14.9 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GtrA PF04138.9 KKK21304.1 - 0.00046 20.1 7.2 0.00046 20.1 5.0 3.9 4 2 0 4 4 4 1 GtrA-like protein DUF872 PF05915.7 KKK21304.1 - 0.065 13.1 0.2 0.34 10.7 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Adeno_E3_14_5 PF04834.7 KKK21304.1 - 7.9 6.9 5.6 19 5.7 0.2 2.8 2 1 0 2 2 2 0 Early E3 14.5 kDa protein zf-H2C2 PF09337.5 KKK21305.1 - 2.2e-23 81.3 4.6 3.9e-23 80.5 3.2 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KKK21305.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KKK21305.1 - 0.00068 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK21305.1 - 0.0022 17.6 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KKK21305.1 - 0.0055 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 KKK21306.1 - 3.8e-80 269.6 22.0 4.7e-80 269.3 15.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK21306.1 - 6.1e-25 87.6 31.6 1.1e-23 83.5 21.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK21306.1 - 1.1e-07 30.4 2.2 1.7e-07 29.8 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Beta-lactamase PF00144.19 KKK21307.1 - 1e-28 100.3 1.1 1.7e-28 99.6 0.8 1.2 1 0 0 1 1 1 1 Beta-lactamase HK PF02110.10 KKK21308.1 - 9.9e-81 270.5 0.3 9.9e-81 270.5 0.2 1.8 2 1 1 3 3 3 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KKK21308.1 - 9.5e-57 191.0 2.5 1.5e-56 190.3 1.7 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Cerato-platanin PF07249.7 KKK21309.1 - 8.3e-28 96.7 2.0 2.2e-25 88.9 1.4 2.0 1 1 0 1 1 1 1 Cerato-platanin Glyco_hydro_16 PF00722.16 KKK21310.1 - 2.9e-08 33.2 0.0 5.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-C2H2 PF00096.21 KKK21318.1 - 5.3e-12 45.3 12.1 2.6e-06 27.4 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK21318.1 - 1.5e-09 37.5 11.5 0.00029 20.9 3.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK21318.1 - 3.8e-07 30.0 11.8 3.1e-06 27.1 3.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KKK21318.1 - 1e-05 25.4 5.2 0.0026 17.8 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK21318.1 - 9.6e-05 22.4 4.9 0.0036 17.4 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KKK21318.1 - 0.01 15.7 8.7 0.015 15.1 0.2 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KKK21318.1 - 0.77 9.9 3.9 8.1 6.6 0.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KKK21318.1 - 2.9 7.7 7.0 1.6 8.5 1.9 2.2 1 1 1 2 2 2 0 BED zinc finger ATP_bind_4 PF01902.12 KKK21319.1 - 3.7e-13 49.3 0.0 2.4e-05 23.8 0.0 3.3 3 1 1 4 4 4 2 ATP-binding region Myc_N PF01056.13 KKK21319.1 - 0.012 14.7 2.8 0.018 14.2 1.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 KKK21319.1 - 0.023 13.9 3.1 0.043 13.0 2.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SR-25 PF10500.4 KKK21319.1 - 0.028 13.8 0.2 0.055 12.9 0.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 KKK21320.1 - 3.9 5.6 11.7 4 5.5 8.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Aldo_ket_red PF00248.16 KKK21321.1 - 1.6e-49 168.2 0.0 1.8e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TEA PF01285.13 KKK21322.1 - 5.6e-148 493.6 0.9 7.2e-148 493.3 0.6 1.1 1 0 0 1 1 1 1 TEA/ATTS domain family DUF3565 PF12088.3 KKK21322.1 - 0.024 14.3 0.0 0.29 10.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) Myb_DNA-binding PF00249.26 KKK21322.1 - 0.079 13.0 0.2 0.33 11.0 0.1 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain RRM_1 PF00076.17 KKK21323.1 - 7e-75 246.6 0.8 9.5e-20 70.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21323.1 - 4e-65 215.7 0.1 1.5e-14 53.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK21323.1 - 6.8e-37 125.1 0.0 1.6e-11 43.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK21323.1 - 1.5e-07 31.0 0.0 0.37 10.6 0.0 3.8 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KKK21323.1 - 0.00044 19.9 0.2 3.7 7.3 0.1 4.6 5 0 0 5 5 5 1 Limkain b1 Dynein_light PF01221.13 KKK21324.1 - 1.4e-35 121.1 8.5 6.6e-28 96.5 0.7 2.0 1 1 1 2 2 2 2 Dynein light chain type 1 TFIID-31kDa PF02291.10 KKK21324.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Response_reg PF00072.19 KKK21341.1 - 5.2e-22 77.9 0.1 1.2e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 KKK21341.1 - 9.9e-21 73.5 0.0 2.3e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KKK21341.1 - 5.4e-18 64.7 0.1 1.6e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KKK21341.1 - 3.7e-11 43.3 0.0 1.3e-07 31.8 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 KKK21341.1 - 5.4e-10 39.2 4.5 0.0012 18.9 0.1 4.1 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.5 KKK21341.1 - 8.2e-06 25.8 0.1 3.6e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KKK21341.1 - 0.0038 16.9 0.0 0.34 10.6 0.0 2.8 2 0 0 2 2 2 1 PAS fold MotA_ExbB PF01618.11 KKK21341.1 - 0.28 10.7 0.0 0.83 9.2 0.0 1.8 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family HSP70 PF00012.15 KKK21361.1 - 6.5e-87 291.8 0.8 8.5e-87 291.4 0.6 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KKK21361.1 - 6.7e-11 41.3 0.2 9.8e-11 40.8 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Myb_DNA-bind_6 PF13921.1 KKK21362.1 - 6.8e-17 61.3 2.7 1.3e-11 44.4 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK21362.1 - 2.4e-12 46.7 7.3 4.6e-09 36.1 0.4 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KKK21362.1 - 0.0022 18.0 1.9 0.016 15.2 1.3 2.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 KKK21362.1 - 0.01 16.0 2.4 2.2 8.5 0.1 3.0 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Ribosomal_S14 PF00253.16 KKK21363.1 - 3.5e-18 64.7 0.2 3.8e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e TauD PF02668.11 KKK21364.1 - 7.8e-16 58.5 0.0 1.5e-07 31.3 0.0 2.2 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family Hydrolase_like PF13242.1 KKK21364.1 - 3.4e-10 39.4 0.1 1.3e-09 37.6 0.1 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KKK21364.1 - 2.6e-09 37.5 0.0 4.5e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK21364.1 - 1.9e-06 28.1 0.0 3.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK21364.1 - 2.5e-05 24.7 0.0 0.0036 17.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CsiD PF08943.5 KKK21364.1 - 0.0042 16.0 0.0 0.0067 15.3 0.0 1.2 1 0 0 1 1 1 1 CsiD Sugar_tr PF00083.19 KKK21365.1 - 5.2e-83 279.1 25.7 1.8e-60 204.8 6.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK21365.1 - 2.1e-19 69.4 33.6 1.6e-11 43.5 5.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK21365.1 - 5.6e-05 21.5 1.3 5.6e-05 21.5 0.9 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DASH_Spc19 PF08287.6 KKK21367.1 - 7.5e-56 187.9 6.5 9.7e-56 187.6 4.5 1.1 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.7 KKK21367.1 - 0.13 12.2 0.0 0.17 11.9 0.0 1.3 1 1 0 1 1 1 0 Mur ligase middle domain IFP_35_N PF07334.8 KKK21367.1 - 1.1 9.2 4.1 5.7 6.9 1.9 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus COG5 PF10392.4 KKK21367.1 - 1.4 8.8 6.3 10 6.0 0.1 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 NmrA PF05368.8 KKK21368.1 - 7.1e-46 156.3 0.1 8e-46 156.1 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK21368.1 - 1e-13 51.6 0.1 1.2e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK21368.1 - 1.3e-05 24.0 0.2 1.7e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KKK21368.1 - 0.0065 16.4 0.1 0.0087 16.0 0.1 1.2 1 0 0 1 1 1 1 TrkA-N domain Arb2 PF09757.4 KKK21369.1 - 2.3e-35 121.6 0.0 3e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Rogdi_lz PF10259.4 KKK21370.1 - 2.1e-73 246.8 0.0 6.1e-73 245.2 0.0 1.7 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein Rsm22 PF09243.5 KKK21370.1 - 2.6e-29 102.1 0.0 1.2e-28 99.9 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 SUR7 PF06687.7 KKK21371.1 - 7.1e-41 140.0 12.7 8.2e-41 139.8 8.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KKK21371.1 - 0.0027 17.4 9.2 0.0027 17.4 6.4 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KKK21371.1 - 0.0076 15.5 3.0 0.012 14.8 2.1 1.4 1 0 0 1 1 1 1 Clc-like GerA PF03323.8 KKK21371.1 - 1 7.4 3.2 1.7 6.6 2.2 1.3 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Fig1 PF12351.3 KKK21371.1 - 1.1 9.0 14.3 0.26 11.1 7.4 1.9 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4064 PF13273.1 KKK21371.1 - 1.8 8.6 12.0 12 6.0 6.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) PerC PF06069.6 KKK21372.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 2 0 0 2 2 2 0 PerC transcriptional activator UDP-g_GGTase PF06427.6 KKK21373.1 - 1.2e-68 230.6 0.0 2e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KKK21373.1 - 0.00033 20.0 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 DS PF01916.12 KKK21374.1 - 6.3e-141 468.7 0.0 7.3e-141 468.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 KKK21374.1 - 0.081 12.0 0.1 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase Aldedh PF00171.17 KKK21375.1 - 5.2e-128 427.2 0.0 3.6e-126 421.2 0.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_2_C PF02836.12 KKK21376.1 - 1.9e-111 371.7 0.0 1.8e-100 335.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KKK21376.1 - 2e-74 248.7 0.5 1.5e-51 174.2 0.1 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 KKK21376.1 - 1.3e-48 165.3 0.0 2.4e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2 PF00703.16 KKK21376.1 - 3.8e-13 49.8 0.6 5.7e-05 23.5 0.1 3.1 2 1 0 2 2 2 2 Glycosyl hydrolases family 2 GMC_oxred_N PF00732.14 KKK21377.1 - 7.2e-52 176.3 0.0 9.7e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK21377.1 - 2.5e-31 108.9 0.1 4.2e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KKK21377.1 - 1.6e-05 24.0 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KKK21377.1 - 0.00011 21.2 0.0 0.0033 16.3 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK21377.1 - 0.00016 21.6 0.1 0.00037 20.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KKK21377.1 - 0.0083 15.0 0.0 0.66 8.7 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KKK21377.1 - 0.0094 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK21377.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK21377.1 - 0.042 12.3 0.0 0.12 10.8 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 KKK21377.1 - 0.072 13.1 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KKK21377.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 KKK21377.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.11 KKK21378.1 - 1.2e-28 99.8 24.8 1.7e-28 99.3 17.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.8 KKK21379.1 - 1e-86 291.0 7.3 1.1e-86 290.8 5.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KKK21379.1 - 0.00092 17.6 0.7 0.0013 17.1 0.1 1.5 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) Amidohydro_1 PF01979.15 KKK21380.1 - 2.4e-56 191.7 0.1 3e-56 191.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KKK21380.1 - 5.4e-15 56.1 0.1 1.8e-11 44.6 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KKK21380.1 - 3.2e-14 52.9 0.1 7.5e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KKK21380.1 - 8.2e-10 38.3 0.0 2.9e-09 36.5 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KKK21380.1 - 0.0054 15.6 0.0 0.021 13.7 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase SurE PF01975.12 KKK21381.1 - 3.1e-33 114.7 1.5 4.3e-33 114.2 1.1 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_hydro_61 PF03443.9 KKK21382.1 - 5.4e-85 284.6 0.4 5.4e-85 284.6 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KKK21382.1 - 5.5e-12 45.1 4.7 5.5e-12 45.1 3.3 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain NPP1 PF05630.6 KKK21383.1 - 1.5e-55 188.1 0.0 1.7e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) RPE65 PF03055.10 KKK21384.1 - 6.8e-105 351.4 0.0 9.6e-105 350.9 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Pectate_lyase_3 PF12708.2 KKK21385.1 - 7e-51 173.5 21.3 2.5e-40 139.0 6.1 4.8 5 0 0 5 5 5 2 Pectate lyase superfamily protein SLT PF01464.15 KKK21385.1 - 0.00016 21.1 0.4 0.0004 19.8 0.1 1.8 2 0 0 2 2 2 1 Transglycosylase SLT domain End_N_terminal PF12218.3 KKK21385.1 - 0.26 10.7 3.0 0.31 10.5 0.0 2.7 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase Glyco_hydro_18 PF00704.23 KKK21386.1 - 3e-32 112.4 0.0 3.7e-29 102.2 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Dickkopf_N PF04706.7 KKK21387.1 - 0.0046 17.0 6.3 0.0046 17.0 4.4 2.7 2 1 0 2 2 2 1 Dickkopf N-terminal cysteine-rich region Aa_trans PF01490.13 KKK21388.1 - 8.8e-39 133.1 33.3 1.1e-38 132.8 23.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2649 PF10854.3 KKK21388.1 - 1.6 8.9 7.8 0.13 12.3 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) DUF1129 PF06570.6 KKK21388.1 - 8.9 5.5 14.3 0.051 12.8 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Ferric_reduct PF01794.14 KKK21389.1 - 1e-17 64.3 14.0 1e-17 64.3 9.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KKK21389.1 - 1.3e-11 44.3 0.0 2.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KKK21389.1 - 1.3e-07 31.6 0.0 1.9e-06 27.8 0.0 2.3 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ctr PF04145.10 KKK21390.1 - 4.7e-41 140.2 3.1 7.1e-41 139.6 2.2 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DUF2164 PF09932.4 KKK21390.1 - 0.054 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) Aegerolysin PF06355.8 KKK21391.1 - 1.3e-42 144.7 0.0 1.6e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Aegerolysin Sugar_tr PF00083.19 KKK21392.1 - 1e-96 324.3 23.5 1.2e-96 324.1 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK21392.1 - 1.5e-33 116.0 45.4 1.4e-28 99.6 17.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.18 KKK21392.1 - 0.68 9.2 13.9 1 8.6 2.0 3.8 4 0 0 4 4 4 0 ABC transporter transmembrane region Fungal_trans PF04082.13 KKK21393.1 - 3.2e-10 39.3 1.2 5.5e-10 38.5 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21393.1 - 9.4e-09 35.0 8.0 3.6e-08 33.1 5.5 2.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MRF_C2 PF13888.1 KKK21393.1 - 0.0065 16.2 0.6 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Myelin gene regulatory factor C-terminal domain 2 Methyltransf_11 PF08241.7 KKK21394.1 - 7.6e-16 58.3 0.0 1.5e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK21394.1 - 2.8e-08 33.6 0.0 4.7e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK21394.1 - 6.2e-08 32.9 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK21394.1 - 1.1e-05 25.7 0.0 2.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK21394.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK21394.1 - 0.00027 21.5 0.0 0.00089 19.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 KKK21394.1 - 0.031 12.9 0.1 0.2 10.3 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) DnaB_bind PF10410.4 KKK21394.1 - 0.052 13.5 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase MetW PF07021.7 KKK21394.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MitMem_reg PF13012.1 KKK21395.1 - 7.1e-40 135.6 0.1 1.5e-39 134.6 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KKK21395.1 - 4.2e-29 100.6 0.1 1.8e-28 98.5 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ADK PF00406.17 KKK21396.1 - 1.8e-60 203.2 0.1 2.3e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KKK21396.1 - 5.4e-15 54.7 0.0 1.3e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 KKK21396.1 - 2.1e-05 24.4 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK21396.1 - 8.7e-05 23.3 0.0 0.00017 22.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK21396.1 - 0.00084 18.4 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KKK21396.1 - 0.0022 18.3 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain CFIA_Pcf11 PF11526.3 KKK21397.1 - 0.0021 18.1 0.1 0.0043 17.1 0.1 1.5 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 RRN7 PF11781.3 KKK21397.1 - 0.0048 16.3 2.6 0.02 14.4 0.3 2.3 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ISL3 PF14690.1 KKK21397.1 - 0.31 11.1 2.1 0.93 9.5 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_4 PF13894.1 KKK21397.1 - 0.41 11.0 3.0 9.9 6.7 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KKK21397.1 - 0.57 9.9 6.7 2 8.2 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GFO_IDH_MocA PF01408.17 KKK21398.1 - 2.9e-18 66.5 0.1 4.5e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KKK21398.1 - 0.0053 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain AMP-binding PF00501.23 KKK21404.1 - 6.8e-07 28.0 0.3 6.7e-06 24.7 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Hid1 PF12722.2 KKK21405.1 - 1.4e-280 933.0 0.0 2.1e-280 932.4 0.0 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KKK21405.1 - 2.5e-84 283.6 0.0 4e-84 283.0 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 KKK21405.1 - 2.6e-36 124.6 0.0 9.3e-36 122.8 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore complex component DASH_Spc19 PF08287.6 KKK21405.1 - 0.054 13.1 0.3 0.13 11.9 0.1 1.7 2 0 0 2 2 2 0 Spc19 KAT11 PF08214.6 KKK21407.1 - 2.8e-104 348.9 0.0 4.5e-104 348.2 0.0 1.3 1 0 0 1 1 1 1 Histone acetylation protein HAD_2 PF13419.1 KKK21410.1 - 2.3e-15 57.2 0.0 9.6e-15 55.2 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK21410.1 - 8e-11 42.7 0.0 3.1e-08 34.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK21410.1 - 5e-08 33.3 0.0 7.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK21410.1 - 7.9e-08 31.9 0.1 1.5e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.5 KKK21410.1 - 0.0051 16.1 0.0 0.18 11.1 0.0 2.7 2 1 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase_6 PF13344.1 KKK21410.1 - 0.04 13.8 0.0 0.13 12.2 0.0 1.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Sporozoite_P67 PF05642.6 KKK21412.1 - 0.038 11.8 0.5 0.049 11.5 0.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GHMP_kinases_N PF00288.21 KKK21412.1 - 0.057 13.4 3.0 0.16 12.0 2.1 1.8 1 0 0 1 1 1 0 GHMP kinases N terminal domain DctQ PF04290.7 KKK21412.1 - 1.2 8.8 9.3 0.23 11.2 1.9 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component ING PF12998.2 KKK21413.1 - 9e-12 45.1 0.0 2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KKK21413.1 - 1.6e-09 37.2 7.4 2.7e-09 36.5 5.1 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KKK21413.1 - 0.07 13.2 1.4 0.15 12.2 1.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4378 PF14309.1 KKK21413.1 - 0.079 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Abhydrolase_1 PF00561.15 KKK21416.1 - 3.2e-10 39.9 0.0 1.8e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK21416.1 - 3.7e-08 33.5 0.0 7.1e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK21416.1 - 0.13 11.9 0.1 1.2 8.9 0.1 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAP_central PF04928.12 KKK21417.1 - 1.6e-104 348.2 0.0 2.1e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KKK21417.1 - 6.1e-50 168.8 0.0 1e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KKK21417.1 - 8e-10 38.9 0.0 2.6e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain PBP_like_2 PF12849.2 KKK21418.1 - 4.2e-08 33.0 2.3 4.2e-08 33.0 1.6 1.8 1 1 1 2 2 2 1 PBP superfamily domain AAL_decarboxy PF03306.8 KKK21418.1 - 0.022 13.8 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase LysR_substrate PF03466.15 KKK21418.1 - 0.052 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain PHY PF00360.15 KKK21420.1 - 1.4e-27 95.9 0.0 2.9e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 KKK21420.1 - 1.4e-18 66.6 0.1 5.4e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK21420.1 - 5.8e-18 64.9 0.0 2.6e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain GAF PF01590.21 KKK21420.1 - 8.7e-13 48.6 0.2 9.1e-12 45.3 0.0 2.7 3 0 0 3 3 3 1 GAF domain HisKA PF00512.20 KKK21420.1 - 6.9e-12 45.1 0.2 2.5e-11 43.4 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 KKK21420.1 - 1.6e-09 38.1 0.0 3.7e-08 33.7 0.0 2.9 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.1 KKK21420.1 - 0.01 15.6 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 KKK21420.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase p450 PF00067.17 KKK21421.1 - 2.4e-74 250.5 0.0 2.9e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 3HCDH_N PF02737.13 KKK21422.1 - 1.7e-26 92.9 0.0 2.6e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KKK21422.1 - 2.5e-19 69.4 0.0 3.9e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain TrkA_N PF02254.13 KKK21422.1 - 0.0062 16.5 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 KKK21422.1 - 0.032 13.9 0.0 0.073 12.8 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KKK21422.1 - 0.052 12.9 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 KKK21423.1 - 1.7e-33 115.7 31.1 2.4e-33 115.3 21.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KKK21425.1 - 3.6e-26 91.6 0.1 6.6e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21425.1 - 6.5e-09 35.5 11.8 1.1e-08 34.8 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_CLD_2 PF14197.1 KKK21425.1 - 0.038 13.9 1.0 0.07 13.0 0.7 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Lzipper-MIP1 PF14389.1 KKK21425.1 - 0.066 13.3 1.3 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Pox_A_type_inc PF04508.7 KKK21425.1 - 0.12 12.2 7.9 0.3 10.9 5.5 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Strep_67kDa_ant PF06100.6 KKK21426.1 - 1.1e-98 330.8 0.0 2.7e-98 329.5 0.0 1.5 1 1 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 KKK21426.1 - 1.7e-05 24.7 0.2 4.4e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK21426.1 - 0.01 14.7 0.1 0.11 11.3 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK21426.1 - 0.071 12.8 0.2 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Melibiase PF02065.13 KKK21427.1 - 5.3e-155 515.9 0.0 6.5e-155 515.6 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 KKK21427.1 - 0.00017 20.5 0.0 0.00027 19.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 GMC_oxred_N PF00732.14 KKK21428.1 - 9.7e-61 205.4 0.0 1.3e-60 205.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK21428.1 - 1e-32 113.4 0.5 3.1e-32 111.8 0.1 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KKK21428.1 - 0.00033 19.6 0.1 0.00059 18.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK21428.1 - 0.00037 19.4 0.2 0.091 11.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK21428.1 - 0.0012 17.8 0.5 0.0032 16.4 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK21428.1 - 0.039 13.9 0.2 0.095 12.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK21428.1 - 0.047 13.7 0.1 3.1 7.7 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NHase_beta PF02211.10 KKK21428.1 - 0.091 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Abhydrolase_6 PF12697.2 KKK21429.1 - 2.7e-19 69.9 0.3 3.6e-19 69.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK21429.1 - 2.5e-09 37.0 0.0 3.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK21429.1 - 7.6e-06 25.7 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK21429.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase CFEM PF05730.6 KKK21430.1 - 0.00017 21.3 4.7 0.00035 20.3 3.3 1.6 1 0 0 1 1 1 1 CFEM domain FUSC_2 PF13515.1 KKK21430.1 - 0.49 10.3 8.7 0.052 13.4 2.2 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein-like ADH_N PF08240.7 KKK21431.1 - 2.8e-24 84.9 0.1 5.2e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK21431.1 - 4.4e-15 55.3 0.0 9.3e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KKK21431.1 - 3.3e-05 23.1 0.1 6.9e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KKK21431.1 - 0.00077 19.0 0.2 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KKK21431.1 - 0.0089 15.7 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KKK21431.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 KKK21431.1 - 0.42 10.4 1.9 0.84 9.4 1.0 1.7 2 0 0 2 2 2 0 ThiF family Ank_2 PF12796.2 KKK21432.1 - 6.2e-75 247.6 7.7 3.1e-16 59.4 0.2 7.2 3 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KKK21432.1 - 6.4e-58 189.8 23.7 1.9e-06 27.4 0.2 14.1 13 0 0 13 13 13 10 Ankyrin repeat Ank_4 PF13637.1 KKK21432.1 - 9.9e-52 172.4 11.1 2.2e-13 50.3 0.1 9.4 5 2 5 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK21432.1 - 2.5e-50 167.3 17.1 1.6e-08 34.5 0.1 11.5 4 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK21432.1 - 1.7e-39 129.8 11.3 1.4e-05 24.8 0.4 13.4 13 0 0 13 13 13 8 Ankyrin repeat NACHT PF05729.7 KKK21432.1 - 7.2e-06 25.7 0.0 2.4e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KKK21432.1 - 6.7e-05 22.9 0.3 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK21432.1 - 0.00014 22.0 0.0 0.00054 20.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK21432.1 - 0.0072 16.5 0.0 0.027 14.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Shigella_OspC PF06128.6 KKK21432.1 - 0.021 14.3 0.0 5.9 6.3 0.0 3.6 3 1 0 3 3 3 0 Shigella flexneri OspC protein Rab3-GTPase_cat PF13890.1 KKK21432.1 - 0.022 14.1 0.2 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit DUF2075 PF09848.4 KKK21432.1 - 0.028 13.3 0.0 0.085 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ZZ PF00569.12 KKK21432.1 - 0.063 12.8 10.0 0.13 11.8 6.9 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type HipA_C PF07804.7 KKK21432.1 - 0.067 13.3 0.0 0.35 11.0 0.0 2.3 1 0 0 1 1 1 0 HipA-like C-terminal domain MFS_1 PF07690.11 KKK21434.1 - 9.6e-22 77.1 65.9 1.4e-18 66.7 32.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KKK21435.1 - 4e-38 131.0 45.2 1.3e-36 126.0 21.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK21435.1 - 2e-15 56.3 14.9 2.4e-15 56.0 10.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Glyoxalase_2 PF12681.2 KKK21436.1 - 1.5e-10 41.6 0.1 1.9e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KKK21436.1 - 6.2e-05 22.9 0.0 0.00021 21.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADH_N PF08240.7 KKK21437.1 - 7.1e-16 57.9 0.6 1.3e-15 57.1 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK21437.1 - 1.3e-13 50.5 0.0 3.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK21437.1 - 5.7e-07 30.4 0.0 1.3e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KKK21437.1 - 0.002 17.5 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MTS PF05175.9 KKK21437.1 - 0.007 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain 2-Hacid_dh_C PF02826.14 KKK21437.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KKK21437.1 - 0.019 15.4 0.0 0.058 13.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 KKK21437.1 - 0.041 14.4 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KKK21437.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.13 KKK21438.1 - 1.3e-06 28.1 7.0 3.2e-06 26.9 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAAG1 PF15354.1 KKK21438.1 - 0.029 14.6 0.0 0.24 11.7 0.0 2.6 2 0 0 2 2 2 0 Kidney-associated antigen 1 Dickkopf_N PF04706.7 KKK21438.1 - 0.26 11.4 5.7 4.1 7.6 0.5 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Methyltransf_2 PF00891.13 KKK21439.1 - 9.9e-26 90.3 0.0 1.4e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KKK21439.1 - 0.0001 22.8 0.0 0.00026 21.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK21439.1 - 0.00018 21.2 0.3 0.02 14.6 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK21439.1 - 0.043 14.2 0.0 0.19 12.2 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Glyco_hydro_11 PF00457.12 KKK21441.1 - 5.7e-73 244.1 19.5 5.7e-73 244.1 13.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 KKK21441.1 - 1.1e-11 44.1 13.1 1.1e-11 44.1 9.0 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain ADH_zinc_N PF00107.21 KKK21442.1 - 2.9e-11 43.0 0.1 5e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK21442.1 - 2.8e-08 33.4 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.12 KKK21442.1 - 0.029 13.2 0.4 0.047 12.5 0.3 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain CutC PF03932.9 KKK21442.1 - 0.14 11.3 0.1 0.27 10.4 0.1 1.4 1 0 0 1 1 1 0 CutC family Gly_transf_sug PF04488.10 KKK21443.1 - 1.1e-12 48.2 0.1 1.9e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KKK21443.1 - 0.0018 16.8 0.3 0.0056 15.2 0.0 1.8 3 0 0 3 3 3 1 TcdA/TcdB catalytic glycosyltransferase domain Cupin_3 PF05899.7 KKK21444.1 - 0.031 13.6 0.1 0.049 13.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF861) HpcH_HpaI PF03328.9 KKK21445.1 - 2.7e-35 121.2 0.0 3.4e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 KKK21445.1 - 0.034 12.7 1.2 0.35 9.4 0.5 1.9 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain AA_permease_2 PF13520.1 KKK21446.1 - 6.2e-43 146.9 50.9 7.8e-43 146.5 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK21446.1 - 1.5e-23 82.9 47.8 1.8e-23 82.6 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.18 KKK21447.1 - 4.6e-26 90.9 3.4 7.7e-26 90.2 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK21447.1 - 3.1e-15 55.8 0.1 5.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.14 KKK21447.1 - 0.11 11.7 0.1 5.3 6.2 0.0 2.2 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain Glycos_transf_1 PF00534.15 KKK21448.1 - 1.8e-08 33.9 0.0 3.8e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 MFS_1 PF07690.11 KKK21449.1 - 3.6e-37 127.8 25.1 3.6e-37 127.8 17.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK21449.1 - 7.1e-16 57.8 7.8 7.1e-16 57.8 5.4 1.8 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 KKK21449.1 - 0.11 10.5 8.2 0.028 12.4 0.5 2.5 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.14 KKK21450.1 - 2.1e-06 27.0 2.2 7.9e-05 21.8 1.5 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK21450.1 - 0.00071 18.5 0.0 0.048 12.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK21450.1 - 0.00071 19.3 0.0 0.0019 17.9 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KKK21450.1 - 0.00094 18.2 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KKK21450.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK21450.1 - 0.034 13.0 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK21450.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KKK21450.1 - 0.065 11.7 0.1 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KKK21450.1 - 0.065 13.2 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK21450.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TPT PF03151.11 KKK21451.1 - 5.5e-31 107.2 12.3 5.5e-31 107.2 8.5 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family AD PF09793.4 KKK21451.1 - 2.7e-23 81.6 0.0 5.2e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain UAA PF08449.6 KKK21451.1 - 0.00015 20.8 18.9 0.00022 20.2 13.1 1.3 1 0 0 1 1 1 1 UAA transporter family REV PF00424.13 KKK21451.1 - 0.0017 18.1 1.8 0.0039 17.0 1.3 1.5 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) EamA PF00892.15 KKK21451.1 - 5.6 7.0 40.3 1.6 8.7 10.4 3.2 3 1 0 3 3 3 0 EamA-like transporter family PBP1_TM PF14812.1 KKK21451.1 - 8.4 6.7 17.1 7.3 6.9 3.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AP_endonuc_2 PF01261.19 KKK21452.1 - 1.2e-26 93.2 0.2 6.7e-26 90.9 0.0 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 KKK21453.1 - 3.2e-43 146.5 0.0 6e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KKK21453.1 - 1.5e-12 47.2 0.0 5.1e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.6 KKK21453.1 - 0.00016 21.4 0.0 0.00056 19.7 0.0 2.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 KKK21453.1 - 0.031 13.3 0.0 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Kinase-like PF14531.1 KKK21453.1 - 0.14 11.1 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like 6PGD PF00393.14 KKK21454.1 - 2.4e-134 447.1 0.0 3e-134 446.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KKK21454.1 - 3.2e-52 176.6 0.0 5e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KKK21454.1 - 0.0049 16.9 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.14 KKK21454.1 - 0.21 10.1 0.0 0.32 9.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase RRM_1 PF00076.17 KKK21455.1 - 2.3e-17 62.3 0.0 3.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21455.1 - 1.5e-11 44.0 0.0 2.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK21455.1 - 0.0044 16.8 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC2_membrane PF01061.19 KKK21456.1 - 4.6e-89 297.1 59.3 1e-48 165.3 17.4 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KKK21456.1 - 6.3e-37 125.3 0.5 6.6e-29 99.6 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KKK21456.1 - 5.5e-35 120.6 0.0 7.6e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KKK21456.1 - 4.6e-13 48.9 43.5 7.4e-07 28.5 15.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KKK21456.1 - 4.2e-08 33.5 0.1 0.0065 16.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KKK21456.1 - 5.9e-08 32.3 0.0 0.00079 18.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK21456.1 - 3.1e-07 31.2 0.0 9.1e-05 23.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK21456.1 - 1.2e-06 28.6 2.9 1.2e-05 25.3 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain ABC_trans_N PF14510.1 KKK21456.1 - 1.5e-06 28.1 0.0 5e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 KKK21456.1 - 2.6e-06 26.8 0.1 0.0032 16.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK21456.1 - 4.5e-06 26.8 0.0 0.0061 16.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KKK21456.1 - 8.5e-06 25.0 0.1 2.8e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KKK21456.1 - 9.2e-06 25.2 0.0 0.00025 20.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KKK21456.1 - 1.5e-05 24.9 0.0 0.0026 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK21456.1 - 0.00022 20.7 0.1 0.65 9.4 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 KKK21456.1 - 0.00033 20.9 0.0 0.012 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KKK21456.1 - 0.00095 19.1 0.2 0.16 11.9 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KKK21456.1 - 0.0012 18.7 0.6 0.0039 17.1 0.1 2.1 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.1 KKK21456.1 - 0.0017 18.7 0.9 0.021 15.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KKK21456.1 - 0.0019 17.8 0.5 0.056 13.1 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 KKK21456.1 - 0.0022 17.6 0.8 0.17 11.6 0.2 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 KKK21456.1 - 0.0037 16.7 1.5 0.86 8.9 0.1 2.8 2 1 0 2 2 2 1 AAA-like domain UPF0079 PF02367.12 KKK21456.1 - 0.004 16.7 1.1 0.054 13.1 0.3 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 KKK21456.1 - 0.0052 16.0 0.1 4.6 6.4 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 KKK21456.1 - 0.014 15.5 0.0 0.56 10.4 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KKK21456.1 - 0.015 14.8 0.5 0.088 12.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 KKK21456.1 - 0.053 12.0 0.7 0.15 10.5 0.3 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 KKK21456.1 - 0.08 12.0 0.2 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 KKK21456.1 - 0.11 11.4 0.8 1.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 KKK21456.1 - 0.13 12.1 0.2 1.3 8.8 0.1 2.7 3 0 0 3 3 3 0 Dynamin family RNA_helicase PF00910.17 KKK21456.1 - 0.13 12.4 0.1 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 KKK21456.1 - 0.15 12.5 0.0 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 KKK21456.1 - 0.24 10.3 0.0 0.6 9.0 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain PduV-EutP PF10662.4 KKK21456.1 - 0.31 10.5 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Citrate_synt PF00285.16 KKK21460.1 - 2.6e-89 299.4 0.0 3.2e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase MmgE_PrpD PF03972.9 KKK21461.1 - 1.5e-153 511.2 1.8 8.6e-113 376.8 0.2 3.6 1 1 1 2 2 2 2 MmgE/PrpD family Sua5_yciO_yrdC PF01300.13 KKK21462.1 - 1.5e-14 53.6 0.0 2.1e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination DUF3848 PF12959.2 KKK21464.1 - 0.046 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Abhydrolase_3 PF07859.8 KKK21465.1 - 1.6e-46 158.5 0.0 2.2e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK21465.1 - 6.6e-11 41.6 0.3 1.9e-10 40.1 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family AATase PF07247.7 KKK21466.1 - 1.2e-13 50.4 0.0 8.2e-12 44.4 0.0 2.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KKK21466.1 - 0.019 13.8 0.0 0.17 10.6 0.0 2.0 2 0 0 2 2 2 0 Condensation domain AATase PF07247.7 KKK21467.1 - 1.5e-12 46.8 0.0 2.4e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Fungal_trans_2 PF11951.3 KKK21468.1 - 1.7e-06 26.8 0.0 2.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIT1_PvcA PF05141.7 KKK21469.1 - 2.6e-78 263.1 0.0 3.7e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.23 KKK21469.1 - 1.2e-25 89.7 0.0 2e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.10 KKK21469.1 - 1.5e-09 36.8 0.0 0.00022 19.8 0.0 2.5 3 0 0 3 3 3 2 Transferase family PP-binding PF00550.20 KKK21469.1 - 1.1e-08 35.2 0.0 2.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site MFS_1 PF07690.11 KKK21470.1 - 5.7e-07 28.5 32.1 1.3e-05 24.1 12.4 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Spermine_synth PF01564.12 KKK21471.1 - 3.7e-93 310.9 0.0 1.1e-82 276.6 0.0 2.1 2 0 0 2 2 2 2 Spermine/spermidine synthase Methyltransf_31 PF13847.1 KKK21471.1 - 0.00011 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK21471.1 - 0.0029 18.1 0.0 0.0058 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK21471.1 - 0.0036 17.7 0.1 0.053 13.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 KKK21471.1 - 0.013 14.7 0.2 0.042 13.0 0.1 1.7 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_24 PF13578.1 KKK21471.1 - 0.16 12.8 0.0 0.31 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rep_fac-A_C PF08646.5 KKK21472.1 - 3.6e-41 140.2 0.5 1.5e-38 131.7 0.1 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KKK21472.1 - 4.8e-22 77.6 0.0 1.2e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KKK21472.1 - 3.1e-14 52.5 0.4 4.7e-10 39.1 0.0 3.7 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 KKK21472.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF223 UCH PF00443.24 KKK21473.1 - 4.6e-33 114.4 0.0 8.7e-32 110.2 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KKK21473.1 - 7.9e-25 86.7 19.4 2e-20 72.6 1.2 3.8 3 2 1 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KKK21473.1 - 1.3e-17 63.0 0.3 3.6e-09 36.1 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 KKK21473.1 - 3.3e-17 62.8 0.0 7.2e-14 51.9 0.0 3.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 KKK21473.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF2315 PF10231.4 KKK21473.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) TerY-C PF15616.1 KKK21473.1 - 0.52 10.2 7.6 1.8 8.5 0.3 3.4 4 0 0 4 4 4 0 TerY-C metal binding domain SH3_1 PF00018.23 KKK21485.1 - 3.1e-11 42.4 0.0 6.6e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK21485.1 - 2.2e-10 39.9 0.0 4.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KKK21485.1 - 1e-06 28.1 0.0 1.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HMG-CoA_red PF00368.13 KKK21486.1 - 5.3e-154 512.3 7.3 6.7e-154 512.0 5.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KKK21486.1 - 1.5e-54 183.8 0.1 2.6e-54 183.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KKK21486.1 - 1.9e-13 50.1 3.0 5.2e-13 48.7 2.1 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KKK21486.1 - 2.2e-08 32.5 5.3 4.1e-08 31.6 3.7 1.3 1 0 0 1 1 1 1 Patched family DUF2304 PF10066.4 KKK21486.1 - 0.065 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Acyl-CoA_dh_1 PF00441.19 KKK21487.1 - 1.5e-41 141.9 0.4 2.3e-41 141.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KKK21487.1 - 7.6e-21 73.3 0.2 1.4e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KKK21487.1 - 2.3e-18 65.7 0.4 4.1e-18 64.9 0.3 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KKK21487.1 - 3.4e-18 66.2 0.0 7.6e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KKK21487.1 - 2e-08 34.5 0.0 3.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CTD PF12815.2 KKK21488.1 - 4e-26 91.8 56.7 7.1e-24 84.5 25.1 3.6 2 1 1 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 KKK21488.1 - 1.1e-25 89.1 0.0 2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KKK21488.1 - 4e-13 48.4 9.1 0.00043 19.8 0.4 4.8 5 0 0 5 5 5 3 KOW motif Spt5_N PF11942.3 KKK21488.1 - 0.0029 18.1 3.4 0.0029 18.1 2.4 5.3 2 2 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal RRM_1 PF00076.17 KKK21489.1 - 9.3e-16 57.2 0.0 1.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21489.1 - 1.8e-11 43.8 0.0 2.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK21489.1 - 1.7e-08 34.1 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ACPS PF01648.15 KKK21491.1 - 1.2e-10 41.2 0.0 2.7e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.14 KKK21492.1 - 4.9e-53 179.5 0.0 5.2e-42 143.6 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KKK21492.1 - 2.8e-08 33.4 0.0 3.7e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KKK21492.1 - 0.00075 18.9 0.0 0.0015 18.0 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 KKK21492.1 - 0.003 17.0 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KKK21492.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase Fapy_DNA_glyco PF01149.19 KKK21496.1 - 3.6e-26 91.8 0.0 6.4e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KKK21496.1 - 4.3e-21 74.4 0.0 7.5e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 KKK21496.1 - 0.022 13.2 1.0 0.036 12.5 0.5 1.6 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) YL1 PF05764.8 KKK21496.1 - 0.074 12.6 14.4 0.11 12.0 10.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Cid2 PF09774.4 KKK21497.1 - 5.2e-51 172.7 0.0 6.1e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Dymeclin PF09742.4 KKK21497.1 - 0.16 10.0 0.0 0.2 9.7 0.0 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein AIRC PF00731.15 KKK21498.1 - 7.1e-59 197.3 2.5 1.4e-58 196.3 1.7 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KKK21498.1 - 1.7e-53 180.4 0.0 6.6e-53 178.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KKK21498.1 - 4.3e-11 42.8 0.0 1.4e-10 41.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KKK21498.1 - 1.6e-06 27.5 0.0 3.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 KKK21498.1 - 0.00026 19.8 0.0 0.17 10.6 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK21498.1 - 0.00039 19.8 0.0 0.0084 15.5 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 KKK21498.1 - 0.0027 16.9 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KKK21498.1 - 0.0075 16.1 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 KKK21498.1 - 0.015 15.6 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain CoA_binding_2 PF13380.1 KKK21498.1 - 0.033 14.3 0.7 18 5.5 0.0 3.6 2 1 1 3 3 3 0 CoA binding domain ATP-grasp_3 PF02655.9 KKK21498.1 - 0.034 14.0 0.0 0.092 12.6 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain 3HCDH_N PF02737.13 KKK21498.1 - 0.041 13.5 0.1 0.12 12.0 0.1 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PrpR_N PF06506.6 KKK21498.1 - 0.083 12.2 1.8 0.14 11.5 0.1 2.1 2 0 0 2 2 2 0 Propionate catabolism activator PPP4R2 PF09184.6 KKK21499.1 - 1.5e-12 47.6 0.3 2.1e-11 43.8 0.2 2.4 1 1 0 1 1 1 1 PPP4R2 PCI PF01399.22 KKK21500.1 - 1.7e-05 25.1 0.0 2.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 PCI domain FMN_dh PF01070.13 KKK21501.1 - 1.8e-124 415.2 1.6 2.1e-124 415.0 1.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KKK21501.1 - 1.9e-10 40.1 1.7 8.5e-09 34.7 0.3 2.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KKK21501.1 - 7.9e-08 31.6 1.9 3.4e-05 22.9 0.1 3.0 2 1 1 3 3 3 2 Conserved region in glutamate synthase ThiG PF05690.9 KKK21501.1 - 2.8e-06 26.5 3.2 0.0055 15.8 0.1 3.2 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 KKK21501.1 - 3.9e-06 26.2 0.7 7.1e-06 25.3 0.5 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 KKK21501.1 - 3.6e-05 23.1 2.7 0.037 13.2 0.2 2.8 2 1 1 3 3 3 2 PcrB family His_biosynth PF00977.16 KKK21501.1 - 0.00012 21.3 0.7 0.0012 18.1 0.1 2.4 2 1 1 3 3 3 1 Histidine biosynthesis protein DHO_dh PF01180.16 KKK21501.1 - 0.00019 20.5 2.5 0.0029 16.6 0.1 2.2 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase Dus PF01207.12 KKK21501.1 - 0.00029 19.7 0.2 0.037 12.8 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ApbA_C PF08546.6 KKK21502.1 - 5.5e-29 100.7 0.0 1.1e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KKK21502.1 - 6.4e-26 90.6 0.1 8.9e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KKK21502.1 - 0.12 12.2 1.4 0.28 10.9 0.7 1.9 2 0 0 2 2 2 0 ThiF family RGS PF00615.14 KKK21503.1 - 2e-11 44.0 0.0 2.1e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribonuc_L-PSP PF01042.16 KKK21504.1 - 5.4e-33 113.3 0.0 6.4e-33 113.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2263 PF10021.4 KKK21505.1 - 3e-33 114.9 0.0 4.5e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 KKK21505.1 - 0.078 12.8 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Macro domain NARP1 PF12569.3 KKK21506.1 - 1.9e-213 709.9 26.4 1.2e-211 704.0 11.6 2.5 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 KKK21506.1 - 5.5e-21 73.9 30.9 5.4e-06 25.9 1.4 8.7 7 2 1 8 8 8 5 TPR repeat TPR_14 PF13428.1 KKK21506.1 - 1.5e-19 68.7 20.6 0.0038 17.7 0.2 11.5 8 3 4 12 12 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KKK21506.1 - 1.7e-18 66.6 33.3 0.0017 18.6 0.3 8.5 7 3 2 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 KKK21506.1 - 7.3e-18 64.7 29.0 0.0018 18.8 1.6 9.7 8 1 2 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 KKK21506.1 - 4.6e-14 51.1 46.2 0.0002 21.0 0.4 11.7 14 0 0 14 14 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 KKK21506.1 - 7.5e-12 45.0 34.0 0.0055 16.6 0.3 8.6 6 3 2 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 KKK21506.1 - 1.2e-09 37.6 15.9 0.092 12.9 0.0 8.4 9 0 0 9 9 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK21506.1 - 1.4e-06 28.3 20.0 0.00016 21.7 1.6 6.0 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KKK21506.1 - 5.3e-06 26.2 14.8 0.006 16.4 1.9 5.9 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK21506.1 - 3.9e-05 23.0 37.9 4.4e-05 22.9 0.3 9.7 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK21506.1 - 0.00011 21.7 23.4 0.016 14.9 0.1 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK21506.1 - 0.00057 19.4 6.9 2.5 8.1 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 KKK21506.1 - 0.0041 16.8 2.5 0.33 10.7 0.1 3.9 3 0 0 3 3 2 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 KKK21506.1 - 0.0087 15.8 4.8 0.73 9.6 0.1 4.4 3 1 1 4 4 4 1 Rapsyn N-terminal myristoylation and linker region BTAD PF03704.12 KKK21506.1 - 0.013 15.8 0.2 0.013 15.8 0.1 4.2 5 0 0 5 5 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.9 KKK21506.1 - 0.041 14.3 3.9 0.4 11.2 0.1 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK21506.1 - 0.047 14.1 25.4 1.2 9.7 0.2 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KKK21506.1 - 1 9.2 13.7 7.3 6.5 0.1 5.6 7 1 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat DUF4449 PF14613.1 KKK21507.1 - 7.3e-64 214.6 0.2 7.3e-64 214.6 0.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) Sec34 PF04136.10 KKK21507.1 - 0.048 13.3 0.1 4 7.1 0.1 2.8 2 0 0 2 2 2 0 Sec34-like family E1-E2_ATPase PF00122.15 KKK21508.1 - 3.3e-51 173.5 0.3 3.3e-51 173.5 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 KKK21508.1 - 1.6e-47 159.4 0.2 7.1e-13 48.5 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 KKK21508.1 - 5.9e-43 147.7 0.2 1.2e-42 146.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK21508.1 - 1.8e-14 54.3 0.0 5.1e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.14 KKK21508.1 - 0.0008 19.2 0.1 1.3 8.9 0.0 4.1 4 1 1 5 5 5 1 B12 binding domain Hydrolase_3 PF08282.7 KKK21508.1 - 0.001 18.6 0.9 0.003 17.1 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GFA PF04828.9 KKK21508.1 - 0.015 15.2 0.2 4.3 7.3 0.0 3.2 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Bromodomain PF00439.20 KKK21509.1 - 4.2e-25 87.4 0.8 7.9e-25 86.5 0.5 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 KKK21509.1 - 1.3e-09 37.9 0.2 5.1e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK21509.1 - 2.2e-09 37.3 0.5 4.9e-09 36.2 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Rad1 PF02144.11 KKK21510.1 - 3.1e-95 318.0 0.2 3.6e-95 317.8 0.1 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Chs3p PF12271.3 KKK21510.1 - 0.16 10.9 0.1 0.72 8.7 0.0 1.9 2 0 0 2 2 2 0 Chitin synthase III catalytic subunit DUF485 PF04341.7 KKK21511.1 - 0.17 11.6 2.8 0.19 11.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 UPF0197 PF05251.7 KKK21511.1 - 0.19 12.0 9.0 0.96 9.8 6.3 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) Claudin_2 PF13903.1 KKK21511.1 - 1.1 8.9 4.8 1.2 8.7 3.3 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction CRAL_TRIO_N PF03765.10 KKK21513.1 - 7.3e-06 26.0 0.0 2.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain IPP-2 PF04979.9 KKK21514.1 - 6.8e-10 39.3 15.8 2.3e-06 27.9 2.2 2.6 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DLH PF01738.13 KKK21516.1 - 1.4e-15 57.1 0.0 3.7e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK21516.1 - 4.2e-06 26.5 0.0 5.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK21516.1 - 0.036 13.9 0.2 0.059 13.2 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 KKK21517.1 - 1.3e-75 254.1 0.0 2.8e-75 253.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KKK21517.1 - 1e-51 175.1 0.8 3.4e-51 173.4 0.0 2.4 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KKK21517.1 - 4.8e-47 160.5 0.0 1e-46 159.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KKK21517.1 - 4.6e-46 157.6 0.2 8.3e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KKK21517.1 - 6.2e-43 146.5 0.0 6.2e-43 146.5 0.0 3.4 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KKK21517.1 - 8.5e-27 93.3 0.0 2.4e-26 91.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KKK21517.1 - 2.1e-18 66.6 0.0 7.6e-18 64.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK21517.1 - 1.1e-11 44.7 0.0 2.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK21517.1 - 6e-11 42.1 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK21517.1 - 9.5e-11 42.2 0.0 4.4e-09 36.9 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK21517.1 - 2e-10 41.0 0.0 5.1e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KKK21517.1 - 3.6e-08 33.5 0.2 1.4e-07 31.6 0.0 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KKK21517.1 - 1.5e-05 24.1 0.0 2.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KKK21517.1 - 0.00017 20.7 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KKK21517.1 - 0.0086 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 KKK21517.1 - 0.014 14.9 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DREV PF05219.7 KKK21517.1 - 0.079 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_PK PF05891.7 KKK21517.1 - 0.48 9.6 0.0 1.4 8.2 0.0 1.7 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Bac_rhamnosid PF05592.6 KKK21520.1 - 3.8e-182 606.0 0.0 4.5e-182 605.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KKK21520.1 - 2.5e-55 186.6 0.0 4.7e-55 185.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_30 PF02055.11 KKK21521.1 - 4.3e-44 150.5 1.8 6e-44 150.0 1.2 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 CSS-motif PF12792.2 KKK21521.1 - 0.03 13.6 0.2 0.067 12.5 0.1 1.6 2 0 0 2 2 2 0 CSS motif domain associated with EAL Glyco_hydro_16 PF00722.16 KKK21522.1 - 1.2e-40 138.7 4.5 2.1e-40 138.0 3.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nop16 PF09420.5 KKK21538.1 - 4.2e-60 202.5 8.0 4.8e-60 202.3 5.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.17 KKK21539.1 - 2.1e-62 210.9 5.0 5.7e-62 209.5 3.5 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.9 KKK21541.1 - 1.3e-108 362.2 0.0 1.7e-108 361.8 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KKK21541.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mito_carr PF00153.22 KKK21542.1 - 1.8e-57 191.0 0.3 2.6e-20 71.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldedh PF00171.17 KKK21543.1 - 1.2e-173 577.7 1.1 7.4e-173 575.1 0.7 1.8 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KKK21543.1 - 0.14 11.3 0.0 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SGL PF08450.7 KKK21544.1 - 1.1e-80 270.5 0.0 1.4e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region LRR_6 PF13516.1 KKK21545.1 - 0.04 13.9 0.1 6.1 7.2 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Kelch_4 PF13418.1 KKK21546.1 - 1e-19 70.0 3.6 3.3e-11 42.7 0.0 5.3 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KKK21546.1 - 3.9e-16 58.7 8.1 4.8e-08 32.9 0.0 5.6 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK21546.1 - 4.7e-13 48.7 4.1 5.8e-05 22.9 0.0 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KKK21546.1 - 8.3e-11 41.2 0.0 0.0089 15.5 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 KKK21546.1 - 2.2e-10 39.8 2.2 0.0016 18.1 0.0 4.6 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 KKK21546.1 - 1.4e-08 34.5 5.8 0.0026 17.8 0.2 5.2 3 1 1 4 4 4 2 Kelch motif WD40 PF00400.27 KKK21547.1 - 4.3e-22 77.1 16.3 3.6e-08 32.9 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 KKK21548.1 - 0.016 15.2 4.3 0.58 10.2 3.0 3.0 1 1 0 1 1 1 0 Cytidylyltransferase AhpC-TSA PF00578.16 KKK21549.1 - 7.6e-35 119.2 0.0 1.3e-34 118.5 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KKK21549.1 - 7.6e-17 60.6 0.3 1.2e-16 60.0 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KKK21549.1 - 2.5e-13 49.7 0.0 3.4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin EVE PF01878.13 KKK21550.1 - 8.5e-49 165.2 0.0 1e-39 135.7 0.0 2.2 1 1 1 2 2 2 2 EVE domain AT_hook PF02178.14 KKK21550.1 - 0.003 17.0 14.5 0.14 11.9 4.1 3.1 2 0 0 2 2 2 2 AT hook motif Acyl_transf_3 PF01757.17 KKK21551.1 - 1.7e-32 112.6 36.7 2.9e-32 111.8 25.5 1.4 1 1 0 1 1 1 1 Acyltransferase family mRNA_triPase PF02940.10 KKK21552.1 - 3.1e-54 183.9 0.0 7.1e-54 182.7 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain BCS1_N PF08740.6 KKK21553.1 - 2.7e-55 186.9 0.3 3.5e-55 186.5 0.2 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KKK21553.1 - 1.3e-18 67.4 0.0 2.2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KKK21553.1 - 3.1e-05 24.7 0.0 7.2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KKK21553.1 - 0.0003 20.2 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KKK21553.1 - 0.00052 19.0 0.0 0.00079 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.1 KKK21553.1 - 0.00055 19.9 0.1 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK21553.1 - 0.00058 19.8 0.1 0.0023 17.9 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.1 KKK21553.1 - 0.00061 20.0 0.0 0.0028 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KKK21553.1 - 0.00079 19.5 0.0 0.0077 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KKK21553.1 - 0.0062 16.4 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK21553.1 - 0.0074 16.0 0.0 0.024 14.3 0.0 2.0 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KKK21553.1 - 0.012 15.7 0.0 0.034 14.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.22 KKK21553.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KKK21553.1 - 0.039 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPV_E1_C PF00519.12 KKK21553.1 - 0.039 12.5 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase DUF258 PF03193.11 KKK21553.1 - 0.043 12.9 0.0 0.22 10.6 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function, DUF258 KaiC PF06745.8 KKK21553.1 - 0.045 12.8 0.0 0.099 11.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KKK21553.1 - 0.066 12.9 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 KKK21553.1 - 0.084 12.4 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KKK21553.1 - 0.099 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Linocin_M18 PF04454.7 KKK21553.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase MMR_HSR1 PF01926.18 KKK21553.1 - 0.15 11.9 0.0 0.46 10.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_11 PF13086.1 KKK21553.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 KKK21555.1 - 6.4e-43 146.5 0.0 8.2e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KKK21555.1 - 5.8e-13 48.8 0.0 1.4e-11 44.3 0.0 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KKK21555.1 - 4e-07 29.8 0.1 0.00016 21.4 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PALP PF00291.20 KKK21562.1 - 2.9e-60 204.1 0.1 3.4e-60 203.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.20 KKK21563.1 - 0.0052 15.9 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 KKK21564.1 - 1.1e-71 241.0 0.0 1.5e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21564.1 - 1.9e-48 164.8 0.0 2.7e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK21564.1 - 2.6e-05 23.3 0.0 8.3e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FAD-oxidase_C PF02913.14 KKK21565.1 - 1.4e-58 198.1 0.0 1.9e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KKK21565.1 - 2.5e-37 127.4 0.5 4.3e-37 126.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.20 KKK21566.1 - 8.9e-22 77.4 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21566.1 - 1e-05 24.7 0.0 2.2e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Oxidored_molyb PF00174.14 KKK21567.1 - 1.2e-51 174.4 0.0 1.8e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KKK21567.1 - 5.2e-28 97.2 2.1 1.2e-27 96.1 1.5 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain DUF4048 PF13257.1 KKK21568.1 - 3.4e-83 279.1 16.5 3.4e-83 279.1 11.5 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) End3 PF12761.2 KKK21568.1 - 0.025 14.2 3.0 0.046 13.3 2.1 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 IncA PF04156.9 KKK21568.1 - 0.032 13.8 0.1 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 IncA protein GrpE PF01025.14 KKK21568.1 - 0.052 13.0 0.4 0.092 12.2 0.3 1.3 1 0 0 1 1 1 0 GrpE Tim17 PF02466.14 KKK21569.1 - 6.1e-53 178.2 6.9 6.1e-53 178.2 4.8 1.9 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Methyltransf_16 PF10294.4 KKK21570.1 - 0.0018 17.7 0.0 0.26 10.7 0.0 2.8 3 0 0 3 3 3 1 Putative methyltransferase Innate_immun PF12782.2 KKK21570.1 - 0.11 11.6 4.1 0.12 11.5 2.9 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family M20_dimer PF07687.9 KKK21575.1 - 2.3e-12 46.6 0.0 3.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Antimicrobial_1 PF08018.6 KKK21575.1 - 0.38 10.6 1.2 0.9 9.4 0.8 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide RRM_1 PF00076.17 KKK21576.1 - 4.8e-46 154.2 0.0 8.3e-17 60.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21576.1 - 2e-27 94.9 0.0 2e-09 37.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK21576.1 - 1.4e-22 79.3 0.0 2.7e-08 33.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KKK21576.1 - 1e-05 25.3 0.0 0.0001 22.0 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 KKK21576.1 - 0.00012 21.7 0.0 0.0089 15.7 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif LRR_6 PF13516.1 KKK21577.1 - 0.0008 19.2 0.8 1.5e+02 2.9 0.0 7.1 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 KKK21577.1 - 0.0092 15.5 7.7 0.072 12.7 0.0 5.2 6 1 1 7 7 7 1 Leucine Rich repeats (2 copies) G-alpha PF00503.15 KKK21578.1 - 1.2e-123 412.6 0.1 1.5e-123 412.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KKK21578.1 - 5.3e-15 55.0 0.2 4.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK21578.1 - 0.00046 19.4 0.1 0.8 8.7 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK21578.1 - 0.0019 18.6 0.0 0.74 10.3 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 KKK21578.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.15 KKK21579.1 - 0 1068.0 0.2 0 1067.8 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase zf-C2HC_2 PF13913.1 KKK21579.1 - 0.46 10.2 1.9 23 4.7 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ABC_membrane_2 PF06472.10 KKK21580.1 - 8.8e-112 372.8 0.8 8.8e-112 372.8 0.6 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KKK21580.1 - 1.7e-17 63.9 0.0 3.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KKK21580.1 - 0.00011 22.3 0.0 0.00032 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KKK21580.1 - 0.0086 15.5 0.0 0.028 13.9 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KKK21580.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KKK21580.1 - 0.024 14.6 0.1 0.097 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 KKK21580.1 - 0.044 12.9 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KKK21580.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HEAT_2 PF13646.1 KKK21581.1 - 1e-14 54.5 0.2 0.11 12.8 0.0 7.4 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.17 KKK21581.1 - 1.6e-07 30.8 13.4 0.071 13.2 0.0 9.5 10 0 0 10 10 10 2 HEAT repeat CLASP_N PF12348.3 KKK21581.1 - 5.5e-05 22.6 1.9 0.36 10.1 0.0 4.7 4 0 0 4 4 4 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KKK21581.1 - 0.036 14.4 0.0 12 6.3 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Transcrip_reg PF01709.15 KKK21582.1 - 2.7e-62 209.9 1.7 3.2e-62 209.7 1.2 1.1 1 0 0 1 1 1 1 Transcriptional regulator CENP-I PF07778.6 KKK21583.1 - 9e-90 301.2 0.1 1.3e-89 300.7 0.1 1.1 1 0 0 1 1 1 1 Mis6 CLPTM1 PF05602.7 KKK21584.1 - 3.4e-173 576.3 0.0 4.2e-173 576.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) adh_short PF00106.20 KKK21585.1 - 3.7e-06 26.9 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Mak16 PF04874.9 KKK21586.1 - 6.7e-24 83.9 12.2 6.7e-24 83.9 8.4 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 KKK21586.1 - 2.2e-06 28.0 0.0 4.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family BUD22 PF09073.5 KKK21586.1 - 2.5e-06 26.8 17.4 3.7e-06 26.2 12.1 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 KKK21586.1 - 0.024 12.5 26.3 0.033 12.1 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 KKK21586.1 - 0.4 9.8 13.5 0.51 9.5 9.4 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Na_trans_assoc PF06512.8 KKK21586.1 - 0.46 10.4 8.7 0.67 9.8 6.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated TFIIF_alpha PF05793.7 KKK21586.1 - 4.2 5.6 36.2 4.8 5.4 25.1 1.2 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mso1_Sec1_bdg PF14475.1 KKK21587.1 - 2.6e-10 39.5 0.0 4.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 FAM220 PF15487.1 KKK21587.1 - 0.07 12.4 2.8 0.12 11.7 2.0 1.5 1 1 0 1 1 1 0 FAM220 family Longin PF13774.1 KKK21588.1 - 3.8e-29 100.0 0.6 5.7e-29 99.4 0.4 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KKK21588.1 - 4.4e-14 51.8 0.0 8.9e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin PilJ PF13675.1 KKK21588.1 - 1.1 9.5 4.6 1.2 9.4 0.4 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ASXH PF13919.1 KKK21589.1 - 1e-20 73.9 7.1 3.6e-15 55.9 0.2 2.3 1 1 1 2 2 2 2 Asx homology domain E1-E2_ATPase PF00122.15 KKK21590.1 - 1.8e-17 63.1 0.0 7.5e-17 61.1 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KKK21590.1 - 8.2e-15 55.7 0.1 6.9e-14 52.7 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK21590.1 - 1.1e-09 38.7 0.3 2.7e-09 37.4 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK21590.1 - 7.8e-06 25.7 0.0 3.1e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK21590.1 - 0.0048 16.4 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Elong_Iki1 PF10483.4 KKK21591.1 - 3.6e-95 318.5 0.0 4.2e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 cobW PF02492.14 KKK21596.1 - 4.5e-33 114.1 0.0 6.4e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KKK21596.1 - 0.012 15.2 0.0 0.16 11.6 0.0 2.6 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Zip PF02535.17 KKK21596.1 - 0.041 12.8 0.5 0.052 12.5 0.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Orn_Arg_deC_N PF02784.11 KKK21597.1 - 1e-76 257.4 0.0 1.4e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KKK21597.1 - 6.1e-31 106.5 0.0 1.3e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain CUE PF02845.11 KKK21598.1 - 2.7e-12 45.9 0.0 4.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 KKK21598.1 - 0.047 13.5 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain DUF3602 PF12223.3 KKK21599.1 - 1.2e-17 64.0 5.4 2.4e-15 56.6 0.6 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) zf-U1 PF06220.7 KKK21600.1 - 7.9e-07 28.5 0.9 1e-06 28.1 0.6 1.2 1 0 0 1 1 1 1 U1 zinc finger Bax1-I PF01027.15 KKK21601.1 - 2e-48 164.7 31.7 2.3e-48 164.5 22.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 KKK21601.1 - 0.025 13.5 2.1 0.089 11.7 0.2 2.3 2 0 0 2 2 2 0 Orbivirus NS3 SUR7 PF06687.7 KKK21616.1 - 6.3e-41 140.2 3.5 7.8e-41 139.9 2.4 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF348 PF03990.9 KKK21616.1 - 0.00068 19.1 3.0 0.0013 18.3 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF348) NolX PF05819.6 KKK21616.1 - 0.06 11.6 0.3 0.27 9.5 0.1 1.8 1 1 1 2 2 2 0 NolX protein Pkinase PF00069.20 KKK21626.1 - 2.7e-34 118.5 0.0 1.6e-33 115.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21626.1 - 4.3e-16 58.7 0.0 4.4e-14 52.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Amidoligase_2 PF12224.3 KKK21627.1 - 9.1e-14 51.6 0.0 1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme AIG2 PF06094.7 KKK21628.1 - 2.5e-07 31.1 0.0 3.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Apc15p PF05841.6 KKK21629.1 - 1.8e-26 93.3 0.4 4.3e-26 92.0 0.3 1.7 1 0 0 1 1 1 1 Apc15p protein Glu_synthase PF01645.12 KKK21630.1 - 1.7e-159 530.6 0.0 2.5e-159 530.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KKK21630.1 - 1.6e-141 471.2 0.0 2.1e-141 470.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KKK21630.1 - 6.2e-94 314.4 0.1 1.1e-89 300.5 0.1 2.5 1 1 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KKK21630.1 - 1.4e-66 223.3 2.1 2.8e-66 222.3 1.4 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KKK21630.1 - 1.6e-22 79.2 0.1 3.9e-22 77.9 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KKK21630.1 - 1.5e-18 67.4 0.0 4.8e-18 65.7 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK21630.1 - 1.1e-10 41.8 0.6 0.00022 21.3 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK21630.1 - 5.8e-09 35.8 0.1 2.1e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK21630.1 - 8e-08 32.5 0.2 0.0001 22.6 0.1 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK21630.1 - 4.5e-07 29.3 0.3 7.4e-07 28.5 0.2 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KKK21630.1 - 4.2e-06 25.8 1.7 0.00012 21.1 0.3 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK21630.1 - 2.2e-05 23.5 0.3 0.00032 19.6 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KKK21630.1 - 7.8e-05 21.3 0.2 7.8e-05 21.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KKK21630.1 - 0.00012 21.2 0.1 0.00023 20.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KKK21630.1 - 0.00013 22.1 0.1 1 9.6 0.1 3.1 3 0 0 3 3 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KKK21630.1 - 0.00037 20.1 0.4 0.017 14.6 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KKK21630.1 - 0.0016 17.6 0.0 0.0039 16.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK21630.1 - 0.0027 16.8 0.1 0.01 14.9 0.1 1.9 2 0 0 2 2 2 1 Thi4 family DJ-1_PfpI PF01965.19 KKK21630.1 - 0.0044 16.4 0.0 0.0092 15.4 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family FMN_dh PF01070.13 KKK21630.1 - 0.007 15.2 1.0 0.032 13.1 0.6 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase FMO-like PF00743.14 KKK21630.1 - 0.029 12.5 0.1 1.8 6.6 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KKK21630.1 - 0.046 13.4 0.0 0.24 11.1 0.0 2.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KKK21630.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KKK21630.1 - 0.062 12.7 0.1 0.62 9.5 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KKK21630.1 - 0.096 13.1 0.1 1.2 9.6 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.17 KKK21630.1 - 0.11 11.3 3.0 0.063 12.1 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KKK21630.1 - 0.12 12.4 0.7 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.17 KKK21631.1 - 1.2e-21 76.8 0.0 7.2e-21 74.2 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 Raptor_N PF14538.1 KKK21632.1 - 9e-05 22.3 0.1 0.00028 20.7 0.0 1.8 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.17 KKK21632.1 - 0.00014 21.6 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DUF3128 PF11326.3 KKK21633.1 - 9e-31 105.8 2.3 1.6e-30 105.0 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.4 KKK21634.1 - 3.2e-169 563.0 0.0 4.4e-169 562.5 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 KKK21634.1 - 1.7e-05 24.6 0.0 4.2e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 KKK21634.1 - 5.8e-05 22.6 0.0 0.00034 20.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK21634.1 - 0.00051 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 KKK21634.1 - 0.0078 16.2 0.0 0.056 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RRM_6 PF14259.1 KKK21634.1 - 0.081 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Helicase_C PF00271.26 KKK21656.1 - 5.9e-12 45.2 0.0 1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNase_PH PF01138.16 KKK21658.1 - 1.4e-16 60.9 0.0 2.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KKK21658.1 - 0.00017 21.4 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 KKK21659.1 - 5.8e-82 275.0 11.1 8.8e-82 274.4 7.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Med22 PF06179.7 KKK21659.1 - 2.6e-22 78.8 2.6 2.6e-22 78.8 1.8 2.1 2 1 1 3 3 3 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF2890 PF11081.3 KKK21659.1 - 0.49 10.4 13.8 0.027 14.5 5.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Glyco_hydro_4C PF11975.3 KKK21659.1 - 6 6.5 6.9 24 4.6 0.0 2.2 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain DHFR_1 PF00186.14 KKK21660.1 - 4.5e-19 68.6 0.0 6.6e-07 29.0 0.0 3.2 2 1 1 3 3 3 3 Dihydrofolate reductase Mito_fiss_reg PF05308.6 KKK21660.1 - 0.1 11.9 3.6 0.13 11.5 2.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KKK21660.1 - 0.73 9.0 5.5 1 8.5 3.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal IL11 PF07400.6 KKK21660.1 - 1.9 7.9 4.2 3.2 7.2 2.6 1.6 1 1 0 1 1 1 0 Interleukin 11 Voltage_CLC PF00654.15 KKK21661.1 - 2.3e-92 309.7 20.5 2.3e-92 309.7 14.2 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel Pectate_lyase PF03211.8 KKK21662.1 - 3e-77 258.8 2.0 3.6e-77 258.5 1.4 1.0 1 0 0 1 1 1 1 Pectate lyase Lipase_GDSL_2 PF13472.1 KKK21663.1 - 1e-23 84.4 0.0 1.2e-23 84.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KKK21663.1 - 8.1e-19 68.3 0.0 9.6e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase G-patch_2 PF12656.2 KKK21663.1 - 0.14 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 DExH-box splicing factor binding site E1-E2_ATPase PF00122.15 KKK21664.1 - 8.1e-18 64.2 0.1 1.6e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KKK21664.1 - 8.7e-18 65.1 0.2 2.3e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK21664.1 - 6.6e-12 46.2 2.7 1.6e-10 41.8 1.9 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK21664.1 - 1.3e-11 44.2 0.0 3.4e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK21664.1 - 0.0039 16.8 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KKK21664.1 - 0.012 15.8 0.2 0.048 13.8 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.19 KKK21665.1 - 2e-11 43.7 0.2 3.2e-11 43.0 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK21665.1 - 3.4e-08 33.1 0.0 5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK21665.1 - 2.1e-07 31.0 0.0 2.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK21665.1 - 2.9e-06 27.3 0.1 4.1e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KKK21665.1 - 0.00024 21.0 0.1 0.00031 20.6 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KKK21665.1 - 0.00067 19.6 0.0 0.00089 19.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KKK21665.1 - 0.00073 19.1 0.1 0.0008 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KKK21665.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase MOZART1 PF12554.3 KKK21666.1 - 7.7e-25 86.1 1.1 9.3e-25 85.8 0.8 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 KKK21666.1 - 0.016 15.3 0.2 0.039 14.0 0.1 1.7 1 1 1 2 2 2 0 SRP54-type protein, helical bundle domain CUE PF02845.11 KKK21667.1 - 1.5e-10 40.2 0.0 2.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain OB_NTP_bind PF07717.11 KKK21668.1 - 1.6e-22 79.4 0.0 3.1e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KKK21668.1 - 2.1e-21 75.8 0.0 4e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK21668.1 - 4.8e-12 45.5 0.0 1.1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KKK21668.1 - 1.6e-05 25.0 0.0 3.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KKK21668.1 - 2e-05 24.1 0.0 4.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.1 KKK21668.1 - 0.0071 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK21668.1 - 0.0082 16.0 0.1 2.9 7.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain T2SE PF00437.15 KKK21668.1 - 0.0087 14.9 0.1 0.038 12.8 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 KKK21668.1 - 0.022 14.5 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 KKK21668.1 - 0.027 13.9 0.0 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 KKK21668.1 - 0.09 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KKK21668.1 - 0.48 9.4 2.8 0.54 9.3 0.1 2.3 2 1 1 3 3 3 0 Zeta toxin PITH PF06201.8 KKK21669.1 - 4e-46 156.5 0.0 4.9e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain NicO PF03824.11 KKK21669.1 - 1.6 8.0 3.6 2.1 7.5 2.5 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Snf7 PF03357.16 KKK21670.1 - 7.4e-36 123.0 3.3 1.1e-35 122.4 2.3 1.3 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.11 KKK21670.1 - 0.034 14.1 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain AAA PF00004.24 KKK21671.1 - 5.2e-79 262.8 0.0 2e-42 144.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK21671.1 - 2.8e-14 53.5 2.6 4.6e-06 26.7 0.0 4.6 3 2 2 5 5 5 2 AAA ATPase domain RuvB_N PF05496.7 KKK21671.1 - 8e-14 51.2 0.0 9.8e-07 28.0 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KKK21671.1 - 2.5e-13 50.2 0.3 0.00051 20.1 0.0 4.9 3 2 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KKK21671.1 - 3.3e-11 44.0 0.0 3.1e-06 28.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KKK21671.1 - 3.7e-11 43.2 0.0 7.3e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KKK21671.1 - 9.4e-11 41.7 0.0 4.5e-05 23.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KKK21671.1 - 1.1e-10 41.5 0.0 0.00025 20.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 KKK21671.1 - 2e-10 40.5 0.3 0.00081 19.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KKK21671.1 - 1.5e-09 37.2 0.0 0.0015 17.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 KKK21671.1 - 4.1e-09 35.6 0.0 6.1e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KKK21671.1 - 1.4e-08 34.3 0.1 0.0077 15.9 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 KKK21671.1 - 6.4e-08 32.7 0.0 0.0059 16.7 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 KKK21671.1 - 8.4e-08 32.3 0.0 0.0045 16.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 KKK21671.1 - 9.8e-08 31.6 0.2 0.011 15.2 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KKK21671.1 - 2.5e-07 30.0 0.6 0.015 14.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KKK21671.1 - 2.8e-07 30.1 4.2 0.38 10.1 0.0 4.5 3 2 2 5 5 4 3 AAA domain NACHT PF05729.7 KKK21671.1 - 3.4e-07 30.0 0.2 0.097 12.3 0.0 4.1 3 1 1 4 4 4 2 NACHT domain AAA_3 PF07726.6 KKK21671.1 - 5.8e-07 29.1 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KKK21671.1 - 1.1e-06 28.9 0.0 0.021 15.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain KaiC PF06745.8 KKK21671.1 - 1.3e-05 24.4 0.1 0.4 9.7 0.0 3.3 2 1 1 3 3 3 2 KaiC Sigma54_activ_2 PF14532.1 KKK21671.1 - 1.7e-05 24.8 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KKK21671.1 - 1.8e-05 25.0 0.0 0.2 11.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter Cytidylate_kin2 PF13189.1 KKK21671.1 - 1.9e-05 24.6 0.0 0.0026 17.6 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family PhoH PF02562.11 KKK21671.1 - 2.5e-05 23.6 0.0 0.091 11.9 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein SKI PF01202.17 KKK21671.1 - 3.5e-05 23.7 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase Sigma54_activat PF00158.21 KKK21671.1 - 6.7e-05 22.4 0.0 0.24 10.8 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KKK21671.1 - 0.00011 22.0 0.0 1.3 8.7 0.0 3.5 2 2 1 3 3 3 2 Archaeal ATPase NB-ARC PF00931.17 KKK21671.1 - 0.00022 20.1 0.0 0.22 10.3 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Rad17 PF03215.10 KKK21671.1 - 0.00028 19.7 0.0 0.12 11.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AFG1_ATPase PF03969.11 KKK21671.1 - 0.00055 18.8 0.0 0.095 11.4 0.0 2.5 2 1 0 2 2 2 1 AFG1-like ATPase Parvo_NS1 PF01057.12 KKK21671.1 - 0.00072 18.5 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 KKK21671.1 - 0.00074 19.3 0.0 1.9 8.2 0.0 2.7 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KKK21671.1 - 0.00089 18.8 0.2 0.87 9.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 KKK21671.1 - 0.0014 18.2 0.0 0.95 8.9 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KKK21671.1 - 0.0019 17.8 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 KKK21671.1 - 0.004 16.1 0.0 0.091 11.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KKK21671.1 - 0.0041 16.6 0.0 1.4 8.3 0.0 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 KKK21671.1 - 0.0042 16.8 0.0 1.7 8.3 0.0 3.1 2 1 1 3 3 3 1 NTPase IPT PF01745.11 KKK21671.1 - 0.0076 15.4 0.0 0.91 8.6 0.0 2.4 2 0 0 2 2 2 1 Isopentenyl transferase AAA_24 PF13479.1 KKK21671.1 - 0.0087 15.6 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 KKK21671.1 - 0.021 14.4 0.0 0.63 9.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.4 KKK21671.1 - 0.022 13.7 0.0 2.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 KKK21671.1 - 0.038 14.3 0.5 2.5 8.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 KKK21671.1 - 0.04 13.5 0.0 13 5.3 0.0 3.1 4 0 0 4 4 3 0 AAA domain KTI12 PF08433.5 KKK21671.1 - 0.078 12.1 0.1 17 4.4 0.0 3.2 3 1 0 3 3 3 0 Chromatin associated protein KTI12 SRPRB PF09439.5 KKK21671.1 - 0.11 11.6 0.0 14 4.8 0.0 2.8 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit He_PIG PF05345.7 KKK21673.1 - 3.5e-15 55.7 10.0 0.00015 21.7 0.0 4.9 4 0 0 4 4 4 4 Putative Ig domain BACON PF13004.2 KKK21673.1 - 0.0069 16.5 4.7 2.1 8.6 0.0 4.0 4 0 0 4 4 4 2 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal Pyridox_oxidase PF01243.15 KKK21685.1 - 1.3e-10 41.1 0.0 4.7e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase WD40 PF00400.27 KKK21686.1 - 2.2e-09 36.8 12.0 1.3e-06 28.0 0.2 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Gryzun-like PF12742.2 KKK21686.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Nucleoporin_N PF08801.6 KKK21686.1 - 0.047 12.4 1.4 0.63 8.7 0.1 2.6 1 1 1 2 2 2 0 Nup133 N terminal like MscS_porin PF12795.2 KKK21686.1 - 0.073 12.3 14.4 0.11 11.7 10.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GAS PF13851.1 KKK21686.1 - 0.17 11.0 7.6 0.26 10.4 5.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3373 PF11853.3 KKK21686.1 - 0.32 9.4 2.4 0.53 8.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Spc7 PF08317.6 KKK21686.1 - 0.65 8.5 6.6 0.95 8.0 4.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF904 PF06005.7 KKK21686.1 - 0.75 10.1 8.0 5.1 7.4 5.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF724 PF05266.9 KKK21686.1 - 0.77 9.3 6.3 0.13 11.8 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 KKK21686.1 - 1.9 8.0 11.3 2.9 7.4 7.8 1.2 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 KKK21686.1 - 8 6.3 12.9 6.3 6.6 6.6 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DeoC PF01791.4 KKK21687.1 - 1.9e-38 132.1 4.1 2.3e-38 131.8 2.8 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 KKK21687.1 - 0.024 13.6 2.7 0.045 12.7 1.8 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KKK21687.1 - 0.049 12.8 0.2 0.096 11.9 0.2 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 KKK21687.1 - 0.087 11.6 3.9 0.18 10.5 2.7 1.7 1 1 0 1 1 1 0 FMN-dependent dehydrogenase TP_methylase PF00590.15 KKK21688.1 - 2.3e-46 158.1 0.1 3.4e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KKK21688.1 - 2.4e-15 56.6 0.0 4.6e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KKK21688.1 - 1.9e-11 43.0 0.0 7.2e-08 31.6 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal CW_binding_2 PF04122.7 KKK21688.1 - 0.1 12.8 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 PCI PF01399.22 KKK21689.1 - 6e-20 71.5 0.0 1.5e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 KKK21689.1 - 0.061 12.6 0.2 0.17 11.1 0.1 1.8 2 0 0 2 2 2 0 Putative aspartate racemase FSH1 PF03959.8 KKK21690.1 - 2.7e-73 245.9 0.0 6e-73 244.7 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KKK21690.1 - 1.3e-10 41.5 1.9 1.9e-10 40.9 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK21690.1 - 3.8e-06 26.7 2.3 1.2e-05 25.1 1.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KKK21690.1 - 0.00068 19.1 0.5 0.87 8.9 0.5 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 KKK21690.1 - 0.096 11.9 2.3 1.1 8.4 1.6 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase Ribosomal_S27e PF01667.12 KKK21691.1 - 5.7e-29 99.4 6.8 7.7e-29 99.0 4.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KKK21691.1 - 0.0067 16.2 1.2 0.0078 16.0 0.8 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 KKK21691.1 - 0.065 12.7 0.7 0.12 11.8 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger CDP-OH_P_transf PF01066.16 KKK21692.1 - 1.4e-16 60.6 5.0 1.4e-16 60.6 3.5 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.8 KKK21693.1 - 8e-38 128.5 5.4 8.6e-28 96.3 0.1 2.6 3 0 0 3 3 3 2 NIPSNAP Radical_SAM PF04055.16 KKK21695.1 - 1.9e-14 54.1 0.0 2.8e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Abhydrolase_6 PF12697.2 KKK21696.1 - 1.3e-09 38.3 0.4 1.8e-09 37.8 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK21696.1 - 2.4e-05 24.0 0.0 5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Helicase_C_2 PF13307.1 KKK21697.1 - 1.9e-52 177.6 0.0 5e-52 176.2 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KKK21697.1 - 4.6e-47 159.6 0.0 7.8e-47 158.8 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Ribosomal_L18e PF00828.14 KKK21697.1 - 1.7e-32 112.4 0.0 4.9e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DEAD PF00270.24 KKK21697.1 - 0.0032 17.0 0.0 0.7 9.3 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Dor1 PF04124.7 KKK21697.1 - 0.0091 14.4 0.7 0.017 13.6 0.5 1.3 1 0 0 1 1 1 1 Dor1-like family Ion_trans_2 PF07885.11 KKK21699.1 - 1.1e-24 85.8 23.0 8.4e-15 54.2 6.3 3.5 3 1 0 3 3 3 2 Ion channel Toxin_49 PF15529.1 KKK21699.1 - 0.031 14.2 1.2 3.9 7.4 0.1 2.4 1 1 1 2 2 2 0 Putative toxin 49 DUF3180 PF11377.3 KKK21699.1 - 2 8.2 8.4 0.82 9.5 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3180) Ion_trans PF00520.26 KKK21699.1 - 5.8 6.1 23.5 1.3 8.2 6.5 3.5 2 2 1 3 3 3 0 Ion transport protein Exo5 PF09810.4 KKK21712.1 - 3e-125 417.7 0.0 4e-125 417.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KKK21712.1 - 0.00027 20.4 0.7 0.0016 17.8 0.5 2.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Transglut_core PF01841.14 KKK21713.1 - 5.5e-11 42.6 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Mito_fiss_reg PF05308.6 KKK21713.1 - 6.6 6.0 20.7 0.6 9.4 4.0 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator WD40 PF00400.27 KKK21714.1 - 4.1e-34 115.2 0.8 3.9e-08 32.8 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KKK21714.1 - 0.0059 16.0 0.0 5.4 6.6 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 KKK21714.1 - 0.0077 14.4 0.0 0.13 10.3 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 NDUF_B12 PF08122.7 KKK21715.1 - 8.5e-19 67.0 2.0 1.1e-18 66.6 1.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Tub_2 PF04525.7 KKK21716.1 - 7.3e-07 28.7 0.0 2.4e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Tubby C 2 CAF1 PF04857.15 KKK21717.1 - 5.5e-63 212.7 0.0 7.4e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Cu_amine_oxid PF01179.15 KKK21718.1 - 1.1e-166 554.7 0.0 1.5e-166 554.2 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KKK21718.1 - 1.5e-21 76.3 0.8 1.9e-20 72.7 0.1 2.3 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KKK21718.1 - 1.1e-13 51.0 0.0 2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Lipase_GDSL PF00657.17 KKK21719.1 - 3.2e-17 63.1 0.3 4e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AMP-binding PF00501.23 KKK21720.1 - 1.2e-72 244.5 0.0 1.6e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK21720.1 - 5.3e-13 49.7 0.2 1.8e-12 48.0 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PPTA PF01239.17 KKK21721.1 - 1.6e-36 122.1 15.4 1.3e-08 33.7 0.0 5.7 5 1 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat NRDE-2 PF08424.5 KKK21721.1 - 0.001 18.0 2.6 0.28 10.0 0.2 2.3 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference MIase PF02426.11 KKK21721.1 - 0.072 12.9 0.1 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Muconolactone delta-isomerase RabGAP-TBC PF00566.13 KKK21722.1 - 2.2e-52 177.6 0.1 8.6e-52 175.7 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Med9 PF07544.8 KKK21722.1 - 3.9 7.2 12.3 0.45 10.2 0.4 3.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 zf-DHHC PF01529.15 KKK21723.1 - 4.4e-36 123.8 1.4 1.3e-35 122.3 1.0 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase SET PF00856.23 KKK21724.1 - 3.2e-18 66.5 0.5 3.2e-18 66.5 0.3 4.2 3 2 0 3 3 3 1 SET domain Ribosomal_L24e PF01246.15 KKK21733.1 - 2.7e-31 107.2 0.4 2.7e-31 107.2 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e WD40 PF00400.27 KKK21734.1 - 2.8e-12 46.0 17.1 0.00012 21.8 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 KKK21734.1 - 0.00026 20.8 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-C3HC4_2 PF13923.1 KKK21734.1 - 4 7.5 18.2 0.4 10.7 9.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.22 KKK21746.1 - 2e-56 187.6 5.9 1.1e-24 85.9 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein O-antigen_lig PF13425.1 KKK21746.1 - 0.028 14.4 0.3 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein IBR PF01485.16 KKK21747.1 - 5.6e-23 80.5 47.3 4.3e-12 45.7 6.1 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KKK21747.1 - 5.5e-06 26.3 7.1 5.5e-06 26.3 5.0 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK21747.1 - 3.7e-05 23.4 5.2 3.7e-05 23.4 3.6 3.5 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 KKK21747.1 - 0.00012 21.6 5.1 0.00012 21.6 3.6 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK21747.1 - 0.0029 17.2 8.4 0.0029 17.2 5.8 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KKK21747.1 - 0.0033 17.0 1.9 0.0033 17.0 1.3 3.6 3 0 0 3 3 3 1 RING-type zinc-finger UN_NPL4 PF11543.3 KKK21747.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 AceK PF06315.6 KKK21747.1 - 0.045 12.0 0.2 0.064 11.5 0.2 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Alpha-L-AF_C PF06964.7 KKK21748.1 - 0.0059 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus MGDG_synth PF06925.6 KKK21748.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase TATR PF03430.8 KKK21750.1 - 1.5 7.3 2.7 2.8 6.4 1.8 1.3 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF3115 PF11312.3 KKK21751.1 - 7.5e-110 366.6 0.0 1.1e-109 366.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Band_7 PF01145.20 KKK21752.1 - 1.1e-24 87.3 7.0 1.2e-24 87.2 3.8 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF2884 PF11101.3 KKK21752.1 - 0.029 13.7 0.7 0.052 12.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) UcrQ PF02939.11 KKK21753.1 - 2.7e-28 97.6 0.0 3.3e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 UcrQ family PX PF00787.19 KKK21754.1 - 2.3e-13 49.9 0.0 6.3e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 KKK21754.1 - 3.1e-07 29.9 7.5 3.1e-07 29.9 5.2 2.1 2 0 0 2 2 2 1 SNARE domain DGF-1_C PF11040.3 KKK21754.1 - 0.056 13.3 1.0 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SIP1 PF04938.7 KKK21755.1 - 4.6e-05 22.8 0.2 0.0015 17.9 0.0 2.6 3 0 0 3 3 3 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3381 PF11861.3 KKK21755.1 - 4.6 6.7 14.7 0.13 11.8 5.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) ArfGap PF01412.13 KKK21756.1 - 9e-35 118.9 0.1 9e-35 118.9 0.1 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 KKK21756.1 - 2.6e-12 46.8 0.9 6e-12 45.6 0.1 2.1 2 0 0 2 2 2 1 PH domain CIA30 PF08547.7 KKK21795.1 - 1.6e-37 128.7 0.0 4.1e-25 88.4 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Sugar_tr PF00083.19 KKK21796.1 - 1.4e-96 323.8 18.3 1.6e-96 323.6 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK21796.1 - 6e-21 74.5 51.6 5.9e-19 67.9 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KKK21796.1 - 0.0011 19.0 4.2 0.59 10.1 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) SAICAR_synt PF01259.13 KKK21797.1 - 4.1e-35 121.0 0.0 5e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase RRN9 PF10680.4 KKK21797.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor SEA PF01390.15 KKK21797.1 - 0.096 12.3 0.0 2.4 7.8 0.0 2.0 2 0 0 2 2 2 0 SEA domain HSP70 PF00012.15 KKK21807.1 - 0.0099 13.8 0.0 0.015 13.2 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KKK21807.1 - 0.044 12.3 0.0 0.098 11.2 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein Indigoidine_A PF04227.7 KKK21822.1 - 8.8e-110 366.5 0.4 3.1e-108 361.4 0.3 2.3 1 1 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KKK21822.1 - 9.9e-20 70.8 1.5 4.6e-11 42.4 0.1 2.8 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.9 KKK21823.1 - 2.9e-123 411.6 0.8 3.2e-123 411.4 0.6 1.0 1 0 0 1 1 1 1 Ribophorin I DLH PF01738.13 KKK21824.1 - 8.2e-05 21.9 0.0 0.0002 20.7 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family SnoaL PF07366.7 KKK21824.1 - 0.001 18.6 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KKK21824.1 - 0.0087 16.4 0.0 0.025 14.9 0.0 1.7 1 1 1 2 2 2 1 SnoaL-like domain Mcp5_PH PF12814.2 KKK21828.1 - 9.6e-21 73.9 0.2 2.3e-20 72.7 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 KKK21828.1 - 0.0099 15.6 14.3 0.066 12.9 3.9 2.3 1 1 0 2 2 2 2 TPR/MLP1/MLP2-like protein Lebercilin PF15619.1 KKK21828.1 - 0.038 13.3 11.9 0.076 12.4 8.2 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HAUS-augmin3 PF14932.1 KKK21828.1 - 0.13 11.4 7.3 0.21 10.7 5.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fib_alpha PF08702.5 KKK21828.1 - 0.33 11.0 1.8 5.7 7.0 0.2 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 KKK21828.1 - 0.4 9.6 8.2 0.69 8.9 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 KKK21828.1 - 0.64 9.8 12.6 0.58 10.0 1.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 KKK21828.1 - 0.66 9.1 14.8 0.69 9.0 1.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 KKK21828.1 - 2.9 7.7 17.4 0.27 11.1 2.9 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KKK21828.1 - 5.1 6.6 15.9 12 5.4 11.0 1.5 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 KKK21828.1 - 8.5 5.2 14.8 12 4.7 9.0 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Glyco_hydro_28 PF00295.12 KKK21829.1 - 8e-49 166.3 6.7 1.3e-48 165.6 4.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KKK21829.1 - 0.42 10.3 16.3 1.1 9.0 9.9 2.2 1 1 1 2 2 2 0 Right handed beta helix region MPC PF03650.8 KKK21830.1 - 7e-35 119.5 0.1 2.6e-29 101.6 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0041) Sel1 PF08238.7 KKK21831.1 - 6.6e-36 121.9 50.2 1.7e-07 31.6 0.1 8.4 9 1 0 9 9 9 7 Sel1 repeat AAA_12 PF13087.1 KKK21832.1 - 7.4e-39 133.2 0.0 1.2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK21832.1 - 3e-07 30.2 0.0 5.5e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK21832.1 - 5.3e-05 22.8 0.0 0.00054 19.6 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain KaiC PF06745.8 KKK21832.1 - 0.048 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.4 KKK21832.1 - 0.075 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KKK21832.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 KKK21832.1 - 0.19 11.1 0.5 33 3.8 0.0 3.5 4 1 1 5 5 5 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KKK21832.1 - 0.42 10.1 0.0 4.1 6.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain LigB PF02900.13 KKK21833.1 - 7.2e-49 166.1 0.0 8.5e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.11 KKK21834.1 - 4.9e-10 38.9 0.0 6.2e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF619 PF04768.8 KKK21835.1 - 7.6e-54 181.6 0.1 1.5e-53 180.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KKK21835.1 - 1.3e-29 102.9 0.0 3.6e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KKK21835.1 - 6.2e-25 88.1 0.0 1.1e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 KKK21835.1 - 0.033 14.0 0.0 0.11 12.3 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 KKK21836.1 - 2.6e-31 107.0 0.4 3.1e-31 106.8 0.2 1.1 1 0 0 1 1 1 1 Synaptobrevin Prominin PF05478.6 KKK21836.1 - 0.025 12.1 0.0 0.032 11.7 0.0 1.1 1 0 0 1 1 1 0 Prominin Cation_ATPase_C PF00689.16 KKK21836.1 - 0.057 12.9 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Ank_2 PF12796.2 KKK21837.1 - 4.8e-164 533.2 5.1 2.5e-15 56.5 0.0 11.7 2 2 11 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 KKK21837.1 - 2.8e-144 462.3 1.5 7.8e-08 31.7 0.0 23.2 23 0 0 23 23 23 23 Ankyrin repeat Ank_4 PF13637.1 KKK21837.1 - 1.2e-124 404.7 7.5 4.1e-13 49.4 0.0 17.5 3 2 16 20 20 20 20 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK21837.1 - 2.9e-99 322.8 17.1 4e-12 45.9 0.0 17.2 5 3 13 19 19 19 19 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK21837.1 - 7.7e-98 310.5 0.1 2.2e-05 24.2 0.0 23.2 23 0 0 23 23 23 19 Ankyrin repeat Shigella_OspC PF06128.6 KKK21837.1 - 0.0003 20.3 0.5 38 3.6 0.0 7.1 5 3 3 9 9 9 0 Shigella flexneri OspC protein CBP4 PF07960.6 KKK21838.1 - 4.4e-38 129.7 1.4 5.6e-38 129.4 0.9 1.0 1 0 0 1 1 1 1 CBP4 HNH_2 PF13391.1 KKK21858.1 - 0.00085 19.0 0.0 0.0031 17.2 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease Fumble PF03630.9 KKK21859.1 - 1.6e-139 464.5 3.9 1.4e-138 461.4 2.7 2.0 1 1 0 1 1 1 1 Fumble Gpi16 PF04113.9 KKK21859.1 - 0.17 9.8 0.0 0.24 9.3 0.0 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component DEAD PF00270.24 KKK21860.1 - 7.8e-44 149.1 0.0 4.1e-43 146.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK21860.1 - 5.9e-22 77.3 0.2 1.3e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KKK21860.1 - 7.5e-05 21.6 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 KKK21860.1 - 0.013 13.9 0.0 0.42 8.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 KKK21860.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain ResIII PF04851.10 KKK21860.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 KKK21860.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Polysacc_deac_1 PF01522.16 KKK21861.1 - 5.8e-20 71.1 0.0 9.7e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KKK21861.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) SIR2 PF02146.12 KKK21861.1 - 0.099 12.3 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Sir2 family CoA_binding_2 PF13380.1 KKK21861.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Metallophos PF00149.23 KKK21862.1 - 1.2e-10 41.1 0.3 4.8e-10 39.1 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK21862.1 - 0.00012 22.0 0.4 0.00027 20.8 0.3 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FMN_dh PF01070.13 KKK21863.1 - 3.7e-120 401.0 0.0 4.9e-120 400.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KKK21863.1 - 7.4e-06 25.0 0.4 4.5e-05 22.5 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KKK21863.1 - 0.00027 20.0 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KKK21863.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KKK21863.1 - 0.056 12.7 0.0 0.35 10.0 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein Aldolase_II PF00596.16 KKK21864.1 - 2.4e-48 164.2 0.2 2.9e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans_2 PF11951.3 KKK21865.1 - 1.5e-58 198.2 4.9 2.2e-58 197.6 3.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21865.1 - 6.5e-10 38.7 6.0 1.4e-09 37.6 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2493 PF10686.4 KKK21865.1 - 0.16 11.5 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) Aldedh PF00171.17 KKK21866.1 - 1.6e-124 415.7 4.0 1.8e-124 415.6 2.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HAD PF12710.2 KKK21867.1 - 9.9e-11 42.1 0.0 1.3e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KKK21867.1 - 0.0014 18.8 0.0 0.0046 17.1 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KKK21867.1 - 0.0064 15.8 0.0 0.022 14.0 0.0 1.8 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) GCD14 PF08704.5 KKK21868.1 - 5.6e-06 26.0 0.3 0.018 14.5 0.0 2.5 3 0 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit 4HBT_2 PF13279.1 KKK21869.1 - 2.3e-23 82.9 0.1 4.4e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KKK21869.1 - 5e-06 26.5 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Methyltransf_25 PF13649.1 KKK21870.1 - 1.2e-07 32.0 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK21870.1 - 4.6e-07 30.2 0.0 8.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK21870.1 - 0.0012 18.8 0.2 0.0035 17.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK21870.1 - 0.0015 17.7 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KKK21870.1 - 0.0016 18.1 0.0 0.0041 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK21870.1 - 0.034 14.7 0.0 0.1 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Complex1_LYR_2 PF13233.1 KKK21871.1 - 2.7e-08 34.2 0.0 2.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 KKK21871.1 - 0.0016 18.5 0.1 0.0021 18.2 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KKK21871.1 - 0.0096 15.7 0.1 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4646 PF15496.1 KKK21872.1 - 0.0009 19.3 0.9 0.0038 17.2 0.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Acetyltransf_1 PF00583.19 KKK21873.1 - 2.4e-14 53.1 0.1 3.8e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK21873.1 - 1.2e-07 31.3 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK21873.1 - 0.0023 18.0 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK21873.1 - 0.0094 15.8 0.2 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK21873.1 - 0.046 13.8 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KKK21873.1 - 0.15 11.6 1.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 KKK21874.1 - 1.6e-09 37.2 0.0 3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KKK21874.1 - 5.1e-08 32.3 3.2 0.086 12.9 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Pkinase_Tyr PF07714.12 KKK21874.1 - 1.3e-06 27.7 0.0 2.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KKK21874.1 - 2.1e-05 24.8 0.1 0.025 15.0 0.0 3.0 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 KKK21874.1 - 0.0043 17.2 0.0 0.28 11.4 0.0 2.9 1 1 3 4 4 4 2 HEAT repeats Kinase-like PF14531.1 KKK21874.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Cnd1 PF12717.2 KKK21874.1 - 0.14 12.0 0.0 0.38 10.5 0.0 1.6 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 LsmAD PF06741.8 KKK21875.1 - 4.6e-27 93.9 3.8 1.1e-26 92.6 2.6 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 KKK21875.1 - 2.6e-17 62.5 0.0 5.4e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.8 KKK21876.1 - 2.5e-156 520.8 4.6 2.5e-156 520.8 3.2 1.9 3 0 0 3 3 3 1 Actin interacting protein 3 Lectin_N PF03954.9 KKK21876.1 - 0.00057 19.3 2.0 0.00069 19.0 0.1 2.2 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain Syntaxin_2 PF14523.1 KKK21876.1 - 0.017 15.1 5.3 2.3 8.3 0.0 3.2 3 0 0 3 3 3 0 Syntaxin-like protein DUF3138 PF11336.3 KKK21876.1 - 0.093 10.8 4.1 0.037 12.1 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF1664 PF07889.7 KKK21876.1 - 3.5 7.4 7.7 1.3 8.8 0.9 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 KKK21877.1 - 5.6e-15 55.1 0.0 1e-14 54.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21877.1 - 0.073 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase DbpA PF03880.10 KKK21878.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain Peptidase_S49_N PF08496.5 KKK21879.1 - 2.6 7.8 7.6 6.5 6.5 3.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Beta_elim_lyase PF01212.16 KKK21880.1 - 1.5e-68 231.0 0.0 1.8e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 KKK21880.1 - 0.0056 15.2 0.0 0.0084 14.6 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Yippee-Mis18 PF03226.9 KKK21881.1 - 0.067 13.2 1.1 0.15 12.1 0.8 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Glyco_transf_34 PF05637.7 KKK21882.1 - 4.5e-16 59.0 0.2 5.7e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Caa3_CtaG PF09678.5 KKK21882.1 - 0.068 12.0 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Pkinase PF00069.20 KKK21883.1 - 4.2e-69 232.5 0.0 6.2e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21883.1 - 3.5e-32 111.4 0.0 5.2e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KKK21883.1 - 1.2e-10 41.3 0.4 5.3e-10 39.2 0.1 2.3 3 0 0 3 3 3 1 FHA domain Kinase-like PF14531.1 KKK21883.1 - 0.00058 18.9 0.0 0.0012 17.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK21883.1 - 0.0031 16.6 0.1 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK21883.1 - 0.013 15.2 0.1 6.4 6.4 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KKK21883.1 - 0.077 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNase_T PF00929.19 KKK21884.1 - 2.1e-26 93.1 0.0 3.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Ribosomal_60s PF00428.14 KKK21884.1 - 0.19 12.1 13.2 9.1 6.7 7.9 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glutaredoxin PF00462.19 KKK21885.1 - 2.3e-18 65.9 0.0 7.7e-17 61.0 0.0 2.5 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KKK21885.1 - 8.4e-15 54.3 0.0 2.4e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 KKK21885.1 - 0.00035 20.6 0.0 0.0016 18.4 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KKK21885.1 - 0.043 14.0 0.0 1.5 9.0 0.0 3.0 2 2 1 3 3 3 0 Thioredoxin-like domain HNH_2 PF13391.1 KKK21886.1 - 3.1e-12 46.0 0.0 7e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease HATPase_c_3 PF13589.1 KKK21887.1 - 1.1e-17 64.0 0.0 1.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KKK21887.1 - 7.9e-09 35.2 0.0 4e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 KKK21887.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NAD_binding_8 PF13450.1 KKK21890.1 - 1.2e-12 47.6 0.0 2.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK21890.1 - 0.0035 16.3 0.2 0.038 12.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KKK21890.1 - 0.012 14.7 0.1 0.023 13.7 0.1 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KKK21890.1 - 0.018 15.4 0.1 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK21890.1 - 0.031 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK21890.1 - 0.032 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KKK21890.1 - 0.038 13.7 0.1 0.79 9.4 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KKK21890.1 - 0.069 12.1 0.1 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK21890.1 - 0.085 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family THRAP3_BCLAF1 PF15440.1 KKK21891.1 - 0.53 8.8 6.0 0.68 8.5 4.1 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Neisseria_TspB PF05616.8 KKK21891.1 - 1.1 7.5 6.8 1.9 6.7 4.7 1.5 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein tRNA-synt_2 PF00152.15 KKK21897.1 - 5.5e-78 262.0 0.0 6.3e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KKK21897.1 - 5.4e-08 32.3 0.1 5.7e-05 22.4 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KKK21897.1 - 0.00049 19.7 0.1 0.7 9.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-codon PF01336.20 KKK21897.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain 2OG-FeII_Oxy PF03171.15 KKK21898.1 - 0.074 13.3 0.0 0.18 12.1 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Clr2 PF10383.4 KKK21899.1 - 6.2e-36 123.4 0.0 1.4e-35 122.3 0.0 1.6 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 ABC_membrane_2 PF06472.10 KKK21900.1 - 3.9e-91 305.0 0.1 7.3e-91 304.1 0.0 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KKK21900.1 - 9.1e-13 48.6 0.0 2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 KKK21900.1 - 0.0017 18.7 1.4 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KKK21900.1 - 0.021 13.8 0.0 0.061 12.3 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KKK21900.1 - 0.029 14.3 0.1 0.07 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KKK21900.1 - 0.03 13.8 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.24 KKK21900.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KKK21900.1 - 0.063 14.1 0.1 0.61 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain PgaD PF13994.1 KKK21900.1 - 0.083 12.3 0.2 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 PgaD-like protein Mg_chelatase PF01078.16 KKK21900.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI D5_N PF08706.6 KKK21910.1 - 0.16 12.0 2.3 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 D5 N terminal like IU_nuc_hydro PF01156.14 KKK21911.1 - 7.2e-37 127.2 0.0 9.5e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Glyco_hydro_16 PF00722.16 KKK21912.1 - 1.3e-41 141.8 5.9 1.3e-41 141.8 4.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SNF2_N PF00176.18 KKK21913.1 - 8.5e-71 238.1 0.3 1.4e-70 237.4 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK21913.1 - 1.3e-11 44.1 0.0 3.8e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KKK21913.1 - 6.9e-09 35.5 5.3 6.9e-09 35.5 3.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK21913.1 - 1.3e-08 34.3 2.5 3e-08 33.2 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KKK21913.1 - 1.3e-07 31.6 0.1 3.6e-06 26.9 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 KKK21913.1 - 2.5e-07 30.4 4.4 5.4e-07 29.3 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 KKK21913.1 - 2.8e-07 30.2 0.0 3.4e-06 26.6 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 KKK21913.1 - 4.1e-06 26.3 3.9 1.1e-05 25.0 2.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK21913.1 - 1.6e-05 24.5 3.2 1.6e-05 24.5 2.2 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KKK21913.1 - 0.00012 21.8 6.2 0.00031 20.5 4.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KKK21913.1 - 0.001 18.6 4.7 0.0024 17.4 3.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KKK21913.1 - 0.0018 17.9 1.8 0.0047 16.6 1.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 KKK21913.1 - 0.73 9.3 5.6 2.7 7.5 3.9 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Ras PF00071.17 KKK21914.1 - 1.6e-41 141.4 0.0 2.1e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK21914.1 - 1.7e-08 34.9 0.0 3.8e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KKK21914.1 - 4.6e-06 25.9 0.1 6.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PDZ_2 PF13180.1 KKK21915.1 - 2.3e-07 30.5 0.0 4.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KKK21915.1 - 1.4e-05 25.2 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 KKK21915.1 - 4.5e-05 23.4 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain HMA PF00403.21 KKK21915.1 - 0.05 13.7 0.1 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Heavy-metal-associated domain RhoGEF PF00621.15 KKK21916.1 - 3.8e-20 72.5 0.6 7.9e-20 71.4 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain Ran_BP1 PF00638.13 KKK21917.1 - 6.6e-14 52.0 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain SCP2 PF02036.12 KKK21918.1 - 1.8e-23 82.7 0.3 2.3e-23 82.3 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KKK21918.1 - 2.2e-08 34.1 0.1 2.7e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal UDG PF03167.14 KKK21919.1 - 8.9e-21 73.9 0.0 1.6e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sporozoite_P67 PF05642.6 KKK21919.1 - 0.011 13.6 1.7 0.014 13.2 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SBDS PF01172.13 KKK21920.1 - 4.1e-24 84.1 0.0 4.7e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 KKK21920.1 - 0.0065 16.2 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 Phage XkdN-like protein Cu-oxidase_3 PF07732.10 KKK21921.1 - 1.2e-39 134.6 1.4 5e-38 129.4 0.0 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK21921.1 - 1.4e-31 108.8 4.2 8.2e-31 106.3 0.1 3.0 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KKK21921.1 - 4.2e-14 52.7 0.0 2.6e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase PhyH PF05721.8 KKK21922.1 - 2.6e-09 37.4 0.0 4.5e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KKK21922.1 - 3.1e-09 35.8 0.1 0.017 13.6 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Peptidase_S10 PF00450.17 KKK21923.1 - 1.4e-94 317.6 0.0 1.8e-94 317.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Phosphoesterase PF04185.9 KKK21924.1 - 1e-74 252.0 4.2 1.4e-74 251.6 2.9 1.1 1 0 0 1 1 1 1 Phosphoesterase family Sugar_tr PF00083.19 KKK21925.1 - 5.2e-39 134.0 25.7 7.4e-22 77.5 7.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK21925.1 - 2.7e-25 88.8 25.0 9.8e-19 67.2 9.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.17 KKK21926.1 - 5.5e-92 309.0 3.0 1.3e-91 307.8 2.1 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Fungal_trans_2 PF11951.3 KKK21927.1 - 4.9e-52 176.8 0.2 6.6e-52 176.3 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21927.1 - 1.9e-12 46.8 25.6 1.4e-06 28.0 4.8 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexokinase_2 PF03727.11 KKK21930.1 - 4.6e-56 189.7 0.0 5.7e-42 143.5 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KKK21930.1 - 1.5e-54 184.4 0.0 2.5e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase AA_permease_2 PF13520.1 KKK21931.1 - 1.1e-53 182.3 56.3 1.3e-53 182.0 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK21931.1 - 2e-20 72.6 46.7 2.6e-20 72.2 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease Catalase PF00199.14 KKK21932.1 - 1.6e-168 560.3 0.0 2e-168 560.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KKK21932.1 - 5.2e-14 51.8 0.0 1.2e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive GMC_oxred_N PF00732.14 KKK21933.1 - 2.4e-55 187.7 0.0 3.2e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK21933.1 - 1e-35 123.1 0.0 1.5e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK21933.1 - 1.5e-05 24.0 1.2 0.041 12.7 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KKK21933.1 - 0.00047 19.1 0.2 0.0015 17.5 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KKK21933.1 - 0.0014 17.5 0.0 0.004 16.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK21933.1 - 0.0019 18.2 0.3 0.024 14.6 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK21933.1 - 0.0055 15.8 0.6 0.019 14.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KKK21933.1 - 0.024 14.5 0.0 0.063 13.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMN_dh PF01070.13 KKK21934.1 - 2.4e-106 355.6 0.1 6e-106 354.2 0.1 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KKK21934.1 - 4e-22 77.7 0.0 8.7e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KKK21934.1 - 1.4e-05 24.1 0.0 2.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KKK21934.1 - 4.7e-05 22.4 0.1 7.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KKK21934.1 - 0.0015 17.7 0.1 0.0032 16.6 0.1 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 KKK21934.1 - 0.032 13.2 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KKK21934.1 - 0.048 12.9 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 KKK21934.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family MFS_1 PF07690.11 KKK21935.1 - 5.2e-30 104.3 33.6 5.2e-30 104.3 23.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KKK21935.1 - 0.0001 22.2 0.2 0.0001 22.2 0.2 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) Plant_vir_prot PF01307.12 KKK21935.1 - 0.031 14.0 0.2 0.12 12.1 0.1 2.0 1 0 0 1 1 1 0 Plant viral movement protein DIOX_N PF14226.1 KKK21936.1 - 2.7e-19 69.8 0.1 4.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK21936.1 - 7e-15 55.1 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 KKK21937.1 - 5.4e-14 51.6 0.0 1.3e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21937.1 - 0.0014 18.5 14.3 0.0014 18.5 9.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glucosamine_iso PF01182.15 KKK21938.1 - 1.6e-22 80.2 0.0 2.4e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.8 KKK21938.1 - 0.019 13.9 0.1 0.028 13.3 0.1 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Zn_clus PF00172.13 KKK21939.1 - 4.9e-06 26.3 8.8 8.9e-06 25.5 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ChlamPMP_M PF07548.6 KKK21939.1 - 0.036 13.7 0.1 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Abhydrolase_3 PF07859.8 KKK21941.1 - 3.8e-10 39.7 0.0 5.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK21941.1 - 4.3e-10 38.9 0.5 2e-09 36.7 0.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KKK21941.1 - 2.6e-07 30.4 0.0 3.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK21941.1 - 1.1e-05 25.3 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KKK21941.1 - 3e-05 22.8 0.0 4.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Chlorophyllase PF07224.6 KKK21941.1 - 0.00025 19.9 0.0 0.00035 19.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KKK21941.1 - 0.003 16.4 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme SKG6 PF08693.5 KKK21942.1 - 0.0013 17.9 1.3 0.0027 16.9 0.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 KKK21942.1 - 0.0026 17.2 0.2 0.0059 16.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) Romo1 PF10247.4 KKK21942.1 - 0.029 14.5 0.2 0.062 13.5 0.1 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 NAGLU PF05089.7 KKK21943.1 - 1.3e-130 435.0 7.6 1.7e-130 434.6 5.3 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 KKK21943.1 - 9.8e-70 234.9 1.8 1.5e-69 234.3 1.2 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 KKK21943.1 - 4.4e-16 58.3 0.0 9.2e-16 57.2 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain FYVE PF01363.16 KKK21944.1 - 4.8e-22 77.6 23.4 7.9e-16 57.7 4.3 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 KKK21944.1 - 0.0088 16.1 12.0 0.067 13.3 0.0 2.8 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KKK21944.1 - 0.016 15.0 6.7 0.016 15.0 4.7 3.7 3 1 1 4 4 4 0 AN1-like Zinc finger Rbsn PF11464.3 KKK21944.1 - 0.02 14.4 0.4 0.075 12.6 0.1 2.1 2 0 0 2 2 2 0 Rabenosyn Rab binding domain zf-C2H2_4 PF13894.1 KKK21944.1 - 0.66 10.4 16.0 3.3 8.2 0.0 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger IBR PF01485.16 KKK21944.1 - 4.2 7.3 19.5 0.18 11.7 2.3 3.2 4 0 0 4 4 4 0 IBR domain Hydrolase PF00702.21 KKK21945.1 - 2.1e-22 80.6 0.0 1e-21 78.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK21945.1 - 2e-21 77.0 0.0 3.7e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KKK21945.1 - 2.6e-20 72.4 0.9 8.7e-20 70.7 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KKK21945.1 - 4e-05 23.4 0.0 0.00085 19.2 0.0 2.5 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK21945.1 - 0.0021 17.6 0.1 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KKK21945.1 - 0.047 12.9 0.3 0.26 10.5 0.0 2.3 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase SAGA-Tad1 PF12767.2 KKK21947.1 - 1.7e-65 221.1 0.0 2.3e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.7 KKK21948.1 - 8.9e-54 181.4 5.7 2.6e-53 179.9 4.0 1.9 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KKK21948.1 - 1.9e-27 93.2 36.0 5.1e-05 23.5 0.3 14.1 6 4 8 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.1 KKK21948.1 - 7.3e-24 83.8 14.0 3.8e-06 27.1 0.3 9.3 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KKK21948.1 - 6.2e-20 71.3 28.8 4.7e-05 23.9 1.9 8.7 8 1 2 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 KKK21948.1 - 6.4e-13 48.1 8.7 0.00068 19.2 0.0 7.4 5 2 2 7 7 7 4 TPR repeat TPR_2 PF07719.12 KKK21948.1 - 1.2e-08 34.2 18.2 0.86 9.6 0.0 9.2 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 KKK21948.1 - 1.3e-06 27.7 1.8 0.27 10.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK21948.1 - 1.5e-05 24.7 7.6 6.9 7.1 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK21948.1 - 3.2e-05 23.3 0.0 1.9 8.4 0.0 6.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK21948.1 - 0.00021 21.1 5.8 2 8.4 0.0 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK21948.1 - 0.017 14.8 4.5 74 3.5 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3808 PF10300.4 KKK21948.1 - 0.096 11.2 0.1 7.5 4.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) TPR_21 PF09976.4 KKK21948.1 - 3.1 7.7 22.8 0.55 10.1 1.4 4.8 3 1 1 5 5 5 0 Tetratricopeptide repeat RabGAP-TBC PF00566.13 KKK21949.1 - 2.6e-49 167.5 0.0 4.5e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 KKK21950.1 - 1.6e-37 126.9 0.2 1.9e-17 62.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21950.1 - 4.3e-29 100.3 0.1 2.1e-13 50.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK21950.1 - 1.3e-14 53.7 0.1 2.9e-06 27.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KKK21950.1 - 0.0052 16.6 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif Med15 PF09606.5 KKK21950.1 - 1.3 7.0 73.1 2.5 6.1 50.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MCRS_N PF13325.1 KKK21950.1 - 1.6 8.1 4.0 0.79 9.1 0.9 1.8 1 1 0 1 1 1 0 N-terminal region of micro-spherule protein PPR_3 PF13812.1 KKK21951.1 - 3.9e-14 51.6 3.3 0.013 15.6 0.0 8.3 10 0 0 10 10 10 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 KKK21951.1 - 1.7e-06 27.9 0.4 0.62 10.0 0.0 5.2 5 1 1 6 6 6 2 PPR repeat family TPR_14 PF13428.1 KKK21951.1 - 0.00011 22.5 1.5 30 5.6 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK21951.1 - 0.0013 19.0 0.8 0.78 10.1 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 KKK21951.1 - 0.0076 16.1 7.0 0.94 9.6 0.0 5.8 7 0 0 7 7 7 1 PPR repeat Ribosomal_S18 PF01084.15 KKK21952.1 - 2.8e-15 55.9 0.1 5.1e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 HTH_Tnp_Mu_1 PF02316.11 KKK21952.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Mu DNA-binding domain WD40 PF00400.27 KKK21953.1 - 6e-51 168.5 24.6 1.1e-08 34.6 0.1 11.5 11 0 0 11 11 11 9 WD domain, G-beta repeat IRF PF00605.12 KKK21953.1 - 0.025 14.3 1.2 2.5 7.9 0.1 2.9 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor CPSF_A PF03178.10 KKK21953.1 - 0.14 11.2 0.0 3.4 6.6 0.0 2.6 2 1 0 2 2 2 0 CPSF A subunit region PQQ_3 PF13570.1 KKK21953.1 - 6.4 7.1 10.6 28 5.1 0.0 5.8 6 1 1 7 7 7 0 PQQ-like domain FUSC_2 PF13515.1 KKK21954.1 - 5.8e-14 52.0 0.6 5.8e-14 52.0 0.4 2.5 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 KKK21954.1 - 2.7e-06 26.3 2.0 0.001 17.8 0.0 2.6 3 0 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 KKK21954.1 - 5.3e-06 25.1 8.6 0.0013 17.2 0.2 3.0 2 1 0 3 3 3 2 Fusaric acid resistance protein family DUF2422 PF10337.4 KKK21954.1 - 0.033 13.0 3.4 0.055 12.2 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2422) Complex1_49kDa PF00346.14 KKK21954.1 - 0.18 10.7 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Ribosomal_S6e PF01092.14 KKK21955.1 - 2.5e-57 191.9 0.6 4.4e-57 191.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Lipase_GDSL PF00657.17 KKK21956.1 - 1.3e-06 28.4 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KKK21956.1 - 0.00033 20.8 0.2 0.00061 19.9 0.1 1.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family HMG_box PF00505.14 KKK21957.1 - 7.8e-23 80.5 1.5 1.5e-22 79.6 1.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KKK21957.1 - 2.3e-08 34.2 0.6 5.5e-08 33.0 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain Fungal_trans PF04082.13 KKK21961.1 - 8.3e-09 34.6 0.0 2.1e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21961.1 - 4.9e-07 29.5 8.4 9.7e-07 28.5 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1688 PF07958.6 KKK21962.1 - 3.8e-166 552.7 0.0 4.3e-166 552.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) SPX PF03105.14 KKK21963.1 - 5.4e-52 177.2 0.1 7.2e-52 176.8 0.1 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 KKK21963.1 - 4.9e-20 71.8 37.4 4.6e-18 65.3 16.2 2.1 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KKK21963.1 - 1.7e-13 49.8 25.8 1.7e-13 49.8 17.9 2.5 1 1 1 2 2 2 2 Citrate transporter Ribosomal_S8e PF01201.17 KKK21964.1 - 8.8e-46 155.3 2.8 1.5e-45 154.5 2.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2470 PF10615.4 KKK21964.1 - 2.4e-20 72.5 0.0 4.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) AA_permease_2 PF13520.1 KKK21966.1 - 7e-44 150.0 41.3 8.9e-44 149.6 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK21966.1 - 3e-26 91.8 38.4 3.8e-26 91.4 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease MRP-L27 PF09809.4 KKK21967.1 - 2.2e-15 56.2 0.2 2.6e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 PARP PF00644.15 KKK21968.1 - 1.3e-11 44.3 0.5 3.6e-11 42.8 0.2 1.7 1 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KKK21968.1 - 4.8e-06 26.0 0.0 1.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK21968.1 - 0.055 13.2 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic E2 family B RWD PF05773.17 KKK21968.1 - 0.057 13.3 0.1 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 RWD domain Glyco_hydro_81 PF03639.8 KKK21969.1 - 8.3e-204 678.5 7.2 1.2e-203 677.9 5.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Na_Ca_ex PF01699.19 KKK21969.1 - 4.3e-43 146.2 34.9 2.3e-22 79.1 8.7 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Utp14 PF04615.8 KKK21970.1 - 2.3e-228 760.0 63.2 2.3e-228 760.0 43.8 2.0 1 1 1 2 2 2 1 Utp14 protein Ribosomal_S7 PF00177.16 KKK21971.1 - 7e-30 103.5 0.0 1.8e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Sipho_Gp37 PF14594.1 KKK21971.1 - 0.097 11.8 0.0 0.3 10.2 0.0 1.7 2 0 0 2 2 2 0 Siphovirus ReqiPepy6 Gp37-like protein KAR9 PF08580.5 KKK21971.1 - 0.14 10.3 5.9 0.2 9.8 4.1 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 CRAL_TRIO PF00650.15 KKK21972.1 - 1e-48 164.8 0.1 2.3e-48 163.6 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KKK21972.1 - 1.8e-12 47.4 0.2 3.8e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK21972.1 - 2.6e-09 37.0 0.2 8.6e-09 35.3 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain HD_3 PF13023.1 KKK21972.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 HD domain ATP-synt_C PF00137.16 KKK21974.1 - 1.6e-25 88.7 30.8 3.7e-14 52.3 6.4 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.20 KKK21975.1 - 6.6e-05 22.1 0.1 9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CAP_N PF01213.14 KKK21993.1 - 0.91 8.7 4.8 1.3 8.2 3.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SOG2 PF10428.4 KKK21993.1 - 2.2 6.8 7.1 2.5 6.6 5.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NIF PF03031.13 KKK21994.1 - 1.3e-50 171.1 0.1 2.6e-50 170.1 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.2 KKK21994.1 - 4.6e-37 125.0 34.6 2.4e-09 36.6 2.6 7.3 1 1 8 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK21994.1 - 1.4e-16 59.9 34.9 2.3e-06 27.2 4.0 5.5 2 1 6 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 KKK21994.1 - 4.1e-11 41.3 30.8 0.44 10.7 0.3 11.9 11 1 1 12 12 12 3 Leucine Rich Repeat LRR_6 PF13516.1 KKK21994.1 - 4.8e-10 38.4 23.2 0.068 13.2 0.0 10.4 8 3 3 11 11 11 3 Leucine Rich repeat LRR_9 PF14580.1 KKK21994.1 - 5.7e-09 35.7 12.4 1e-05 25.1 2.1 3.9 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 KKK21994.1 - 1.9e-07 30.1 19.3 1.6 9.2 0.2 9.4 9 1 1 10 10 10 3 Leucine rich repeat Gly_transf_sug PF04488.10 KKK21996.1 - 3.4e-11 43.4 0.0 8.8e-11 42.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Myco_arth_vir_N PF09610.5 KKK21996.1 - 0.068 13.1 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF3989 PF13150.1 KKK21996.1 - 0.11 11.9 1.7 4.1 6.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) bZIP_2 PF07716.10 KKK21997.1 - 1.1e-12 47.5 13.5 2.1e-12 46.6 9.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KKK21997.1 - 4.6e-05 23.2 15.1 8.6e-05 22.4 10.2 1.7 1 1 0 1 1 1 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 KKK21997.1 - 0.00056 19.7 1.1 0.00085 19.1 0.2 1.7 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein DUF4094 PF13334.1 KKK21997.1 - 0.024 14.9 1.2 0.052 13.9 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF3552 PF12072.3 KKK21997.1 - 0.11 11.7 8.7 0.14 11.3 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fungal_trans PF04082.13 KKK21998.1 - 5.6e-25 87.6 0.1 5.6e-25 87.6 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21998.1 - 8.4e-05 22.4 9.5 0.00014 21.6 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec63 PF02889.11 KKK21999.1 - 9.9e-194 642.5 0.0 7e-107 357.2 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KKK21999.1 - 1.2e-53 181.0 0.1 8.1e-31 106.7 0.0 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase Peptidase_S9 PF00326.16 KKK21999.1 - 3.6e-49 166.8 0.0 9.5e-49 165.5 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family ResIII PF04851.10 KKK21999.1 - 6.4e-16 58.7 0.0 7.6e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK21999.1 - 3.4e-09 36.4 0.0 1.5e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Abhydrolase_5 PF12695.2 KKK21999.1 - 6.6e-09 35.6 0.0 2.2e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KKK21999.1 - 1.4e-05 25.2 0.8 0.055 13.6 0.1 3.7 3 1 0 3 3 3 2 AAA domain PhoH PF02562.11 KKK21999.1 - 0.0012 18.1 0.0 0.16 11.2 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 KKK21999.1 - 0.0017 18.0 0.0 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AXE1 PF05448.7 KKK21999.1 - 0.002 16.7 0.2 0.11 11.0 0.0 2.6 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) AAA_10 PF12846.2 KKK21999.1 - 0.0023 17.3 0.1 6.9 6.0 0.0 4.0 4 0 0 4 4 4 1 AAA-like domain T2SE PF00437.15 KKK21999.1 - 0.0051 15.7 0.0 1 8.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 KKK21999.1 - 0.031 13.6 0.1 3.2 7.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein MutS_V PF00488.16 KKK22000.1 - 1.3e-83 280.0 0.0 2e-83 279.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KKK22000.1 - 3.2e-41 141.3 5.2 6.6e-41 140.3 3.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KKK22000.1 - 3.1e-21 75.5 0.0 1e-20 73.8 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KKK22000.1 - 0.00019 21.4 0.0 0.00048 20.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KKK22000.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 KKK22000.1 - 0.019 15.2 0.2 0.7 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KKK22000.1 - 0.027 14.0 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain HTH_AsnC-type PF13404.1 KKK22001.1 - 0.04 13.4 0.1 0.082 12.4 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MFS_1 PF07690.11 KKK22002.1 - 4.5e-39 134.1 45.2 6.2e-39 133.7 30.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK22002.1 - 7.3e-19 67.3 11.2 1.8e-18 66.0 7.7 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK22002.1 - 5.2e-14 51.6 15.3 2.5e-12 46.1 4.6 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter ADH_N PF08240.7 KKK22003.1 - 4.8e-26 90.6 4.1 7.6e-26 90.0 2.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK22003.1 - 1.2e-15 57.2 0.0 2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KKK22003.1 - 0.0076 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding ELFV_dehydrog PF00208.16 KKK22003.1 - 0.0077 15.8 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.1 KKK22003.1 - 0.01 16.7 0.0 0.031 15.1 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KKK22003.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GCC2_GCC3 PF07699.8 KKK22003.1 - 0.046 13.3 1.4 0.25 10.9 0.5 2.2 2 0 0 2 2 2 0 GCC2 and GCC3 Ureidogly_hydro PF04115.7 KKK22004.1 - 2.2e-51 173.4 0.0 2.2e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 Ureidoglycolate hydrolase Myc_N PF01056.13 KKK22004.1 - 0.042 13.0 0.4 0.06 12.4 0.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region AMP-binding PF00501.23 KKK22005.1 - 1.4e-41 142.2 0.0 1.4e-40 138.9 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme FeoA PF04023.9 KKK22005.1 - 0.073 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 FeoA domain Presenilin PF01080.12 KKK22007.1 - 0.035 12.9 1.1 0.039 12.7 0.8 1.1 1 0 0 1 1 1 0 Presenilin Drc1-Sld2 PF11719.3 KKK22007.1 - 2.3 7.2 9.9 3 6.8 6.8 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein KAR9 PF08580.5 KKK22007.1 - 2.5 6.2 7.0 2.9 6.0 4.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PAN_3 PF08277.7 KKK22007.1 - 3.1 7.4 7.5 5.3 6.7 5.2 1.5 1 1 0 1 1 1 0 PAN-like domain Macoilin PF09726.4 KKK22007.1 - 5 5.2 7.4 5.8 5.0 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein CaMKII_AD PF08332.5 KKK22031.1 - 0.0078 16.1 0.0 0.014 15.2 0.0 1.4 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association DUF4440 PF14534.1 KKK22031.1 - 0.066 13.4 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Ank_2 PF12796.2 KKK22032.1 - 4.8e-13 49.2 0.1 6.3e-09 36.0 0.1 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KKK22032.1 - 2.3e-12 46.0 1.2 8.2e-09 34.8 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KKK22032.1 - 4.4e-12 46.1 0.2 3.9e-06 27.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK22032.1 - 4.9e-12 45.6 0.3 5.8e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK22032.1 - 3.3e-10 39.1 0.5 0.00013 21.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 KKK22032.1 - 0.00015 21.3 0.0 0.00054 19.5 0.0 1.9 1 0 0 1 1 1 1 KilA-N domain HALZ PF02183.13 KKK22032.1 - 0.1 12.3 3.5 0.9 9.3 0.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper NDUF_B7 PF05676.8 KKK22033.1 - 7.3e-33 111.8 5.4 8.6e-33 111.5 3.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KKK22033.1 - 0.0063 16.2 2.7 0.0086 15.8 1.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCS PF03074.11 KKK22034.1 - 3.2e-154 513.4 0.0 9.5e-154 511.9 0.0 1.7 1 1 0 1 1 1 1 Glutamate-cysteine ligase AA_permease_2 PF13520.1 KKK22036.1 - 3.6e-42 144.3 34.5 6.3e-42 143.5 23.9 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK22036.1 - 9.7e-18 63.7 29.4 1.6e-17 63.0 20.3 1.3 1 0 0 1 1 1 1 Amino acid permease DUF1469 PF07332.6 KKK22036.1 - 0.68 9.6 15.6 0.95 9.2 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) DUF829 PF05705.9 KKK22043.1 - 1e-53 182.5 0.0 1.8e-53 181.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Rad51 PF08423.6 KKK22043.1 - 2e-23 82.6 0.0 3.7e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KKK22043.1 - 2.6e-11 43.2 0.0 5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KKK22043.1 - 3.7e-09 36.0 0.0 6.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.16 KKK22043.1 - 0.0062 15.6 0.0 0.0099 14.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Pox_A32 PF04665.7 KKK22043.1 - 0.21 10.8 0.1 0.4 9.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein PAXNEB PF05625.6 KKK22043.1 - 0.22 10.3 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 PAXNEB protein IGPD PF00475.13 KKK22045.1 - 1.3e-56 190.5 0.3 1.6e-56 190.1 0.2 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.6 KKK22045.1 - 0.16 8.5 0.0 0.2 8.1 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Hat1_N PF10394.4 KKK22046.1 - 6.6e-50 169.3 0.1 1.1e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Zip PF02535.17 KKK22047.1 - 1.4e-38 132.7 10.7 8.6e-29 100.5 2.8 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter ABC2_membrane_5 PF13346.1 KKK22047.1 - 1.6 7.9 8.5 0.08 12.2 1.0 2.3 3 0 0 3 3 3 0 ABC-2 family transporter protein 3HCDH_N PF02737.13 KKK22048.1 - 4.9e-23 81.6 0.8 2.9e-21 75.9 0.0 2.3 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KKK22048.1 - 5.4e-10 39.5 0.0 2.3e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain LSM PF01423.17 KKK22049.1 - 7.6e-17 60.6 0.0 1.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KKK22049.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.6 KKK22049.1 - 7.2 4.9 8.1 8.7 4.7 5.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DSPc PF00782.15 KKK22050.1 - 5.5e-10 38.9 0.0 1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KKK22050.1 - 0.0046 16.3 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KKK22050.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Cellulose_synt PF03552.9 KKK22050.1 - 0.18 10.0 0.0 0.25 9.6 0.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Mito_fiss_reg PF05308.6 KKK22050.1 - 3.9 6.7 7.3 11 5.3 2.8 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator PLA2_B PF01735.13 KKK22051.1 - 1.7e-26 92.4 0.0 3e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Lysophospholipase catalytic domain RE_NgoPII PF09521.5 KKK22051.1 - 0.23 10.1 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 NgoPII restriction endonuclease Exo70 PF03081.10 KKK22052.1 - 5.3e-78 262.3 0.0 8.2e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Lyase_1 PF00206.15 KKK22053.1 - 5.2e-21 75.1 0.0 9.9e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KKK22053.1 - 5.6e-17 61.5 0.0 1.6e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus PPR_3 PF13812.1 KKK22054.1 - 1.2e-14 53.2 0.8 0.09 13.0 0.1 8.2 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 KKK22054.1 - 3.2e-14 52.6 0.1 0.0013 18.6 0.0 6.6 4 3 3 7 7 7 3 PPR repeat family PPR PF01535.15 KKK22054.1 - 1.7e-09 36.9 2.6 0.035 14.0 0.1 5.5 6 0 0 6 6 6 3 PPR repeat PPR_1 PF12854.2 KKK22054.1 - 0.016 14.6 0.0 0.41 10.1 0.0 2.9 3 0 0 3 3 3 0 PPR repeat AIM24 PF01987.12 KKK22055.1 - 1.7e-46 158.4 0.0 2.3e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ABC_tran PF00005.22 KKK22056.1 - 7.8e-35 120.1 0.0 1.6e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KKK22056.1 - 1.3e-34 119.8 11.4 1.8e-34 119.4 7.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KKK22056.1 - 6.8e-07 29.5 0.0 0.013 15.5 0.0 2.5 2 1 1 3 3 3 2 AAA domain ABC_ATPase PF09818.4 KKK22056.1 - 9e-05 21.2 0.0 0.0013 17.3 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class SMC_N PF02463.14 KKK22056.1 - 9.7e-05 21.6 0.1 0.082 12.1 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KKK22056.1 - 0.00015 21.8 0.0 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK22056.1 - 0.00037 20.6 0.1 0.0027 17.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK22056.1 - 0.00038 21.2 0.0 0.00097 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK22056.1 - 0.00095 19.0 0.0 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KKK22056.1 - 0.0017 17.8 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KKK22056.1 - 0.0024 17.2 0.0 0.015 14.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KKK22056.1 - 0.0033 16.6 0.0 0.0067 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KKK22056.1 - 0.0038 16.7 0.1 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KKK22056.1 - 0.007 16.5 0.0 0.1 12.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KKK22056.1 - 0.0088 16.0 0.0 0.047 13.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 KKK22056.1 - 0.012 15.0 0.0 0.052 12.9 0.0 1.9 1 1 1 2 2 2 0 AAA-like domain AAA_33 PF13671.1 KKK22056.1 - 0.016 15.0 0.2 0.65 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KKK22056.1 - 0.018 15.3 0.3 0.051 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KKK22056.1 - 0.032 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain GPAT_N PF14829.1 KKK22056.1 - 0.061 13.0 0.0 6.7 6.4 0.0 3.2 3 0 0 3 3 3 0 Glycerol-3-phosphate acyltransferase N-terminal Rad17 PF03215.10 KKK22056.1 - 0.064 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 KKK22056.1 - 0.083 11.9 0.6 0.47 9.5 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin SbcCD_C PF13558.1 KKK22056.1 - 0.09 12.6 1.8 0.37 10.7 0.2 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.11 KKK22057.1 - 6.1e-20 71.2 26.4 7e-20 71.0 17.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK22057.1 - 0.002 16.7 12.6 0.011 14.3 8.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter BUD22 PF09073.5 KKK22101.1 - 3.7e-110 368.9 23.2 4.3e-110 368.7 16.1 1.0 1 0 0 1 1 1 1 BUD22 Fungal_trans PF04082.13 KKK22102.1 - 2.3e-26 92.2 0.0 4e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22102.1 - 3.4e-06 26.8 9.4 6.9e-06 25.8 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Velvet PF11754.3 KKK22106.1 - 0.069 12.7 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Velvet factor Cyt-b5 PF00173.23 KKK22113.1 - 5e-19 67.8 0.0 5.5e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain K_oxygenase PF13434.1 KKK22114.1 - 2.1e-107 358.9 0.0 2.7e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KKK22114.1 - 1.8e-11 44.4 0.0 7.2e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK22114.1 - 6.7e-08 32.4 0.1 6.4e-06 26.0 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK22114.1 - 0.00019 21.4 0.0 0.022 14.6 0.0 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 KKK22114.1 - 0.045 12.8 0.0 6.1 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Pkinase PF00069.20 KKK22115.1 - 1.3e-41 142.4 0.0 2.3e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22115.1 - 4.2e-24 85.0 0.0 6.7e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KKK22115.1 - 0.67 8.6 0.0 0.98 8.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase OB_NTP_bind PF07717.11 KKK22116.1 - 1.9e-29 101.7 0.0 5.3e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KKK22116.1 - 9.6e-26 89.7 0.7 4.5e-25 87.6 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK22116.1 - 1.8e-12 46.9 0.0 5.1e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK22116.1 - 2.8e-07 30.1 0.1 7e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK22116.1 - 4.9e-05 23.4 0.0 0.00016 21.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KKK22116.1 - 6.6e-05 21.9 0.0 0.00014 20.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KKK22116.1 - 0.0084 15.5 0.1 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 KKK22116.1 - 0.098 12.7 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain SSP160 PF06933.6 KKK22116.1 - 0.17 9.8 8.3 0.27 9.1 5.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mannitol_dh PF01232.18 KKK22116.1 - 0.2 11.5 1.2 0.73 9.7 0.1 2.4 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain ABC_tran PF00005.22 KKK22116.1 - 0.21 11.8 2.2 0.85 9.9 0.1 2.7 1 1 1 2 2 2 0 ABC transporter AAA_23 PF13476.1 KKK22116.1 - 0.25 11.6 0.0 0.25 11.6 0.0 3.7 1 1 1 3 3 1 0 AAA domain Abhydrolase_5 PF12695.2 KKK22122.1 - 1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK22122.1 - 0.00018 21.2 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KKK22122.1 - 0.00024 21.0 2.7 0.00054 19.9 1.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KKK22122.1 - 0.0028 17.2 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 KKK22122.1 - 0.012 14.9 0.0 0.03 13.6 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 KKK22122.1 - 0.033 13.1 0.1 0.066 12.1 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.11 KKK22122.1 - 0.055 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chs3p PF12271.3 KKK22123.1 - 6.5e-123 409.3 13.9 3.5e-102 341.3 5.5 2.0 1 1 1 2 2 2 2 Chitin synthase III catalytic subunit DUF3382 PF11862.3 KKK22123.1 - 2 8.3 7.5 0.63 9.9 2.6 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) Ribosomal_S6 PF01250.12 KKK22124.1 - 9.8e-08 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 MerR_1 PF13411.1 KKK22124.1 - 0.018 14.8 0.0 0.077 12.7 0.0 1.9 2 0 0 2 2 2 0 MerR HTH family regulatory protein 4HBT_3 PF13622.1 KKK22125.1 - 1.2e-50 172.6 0.0 1.5e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KKK22125.1 - 0.0001 21.9 0.2 0.56 9.8 0.0 3.8 2 2 1 3 3 3 2 Acyl-CoA thioesterase WD40 PF00400.27 KKK22125.1 - 0.076 12.9 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat GCV_H PF01597.14 KKK22126.1 - 3e-37 127.0 0.5 3.6e-37 126.7 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KKK22126.1 - 0.062 12.9 0.3 0.15 11.6 0.1 1.7 1 1 0 1 1 1 0 Biotin-requiring enzyme bZIP_1 PF00170.16 KKK22127.1 - 3.1e-08 33.4 7.9 5.4e-08 32.6 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK22127.1 - 0.0033 17.2 8.3 0.0057 16.4 5.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK22127.1 - 1.7 8.9 11.9 0.045 14.0 3.4 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Abhydrolase_5 PF12695.2 KKK22128.1 - 1.2e-07 31.6 0.0 2.1e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK22128.1 - 9.5e-07 28.9 0.2 5.5e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4599 PF15371.1 KKK22128.1 - 0.089 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) DUF3336 PF11815.3 KKK22130.1 - 5.7e-46 155.6 1.0 9.1e-46 154.9 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KKK22130.1 - 5.3e-22 78.7 0.0 9.4e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase PNP_UDP_1 PF01048.15 KKK22131.1 - 5.3e-38 130.3 0.1 6.4e-38 130.0 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily 6PGD PF00393.14 KKK22132.1 - 3.3e-60 203.7 0.0 5.8e-60 202.9 0.0 1.3 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KKK22132.1 - 1.5e-28 99.7 0.1 2.9e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KKK22132.1 - 1.1e-05 25.1 0.3 1.8e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KKK22132.1 - 0.00098 18.8 0.1 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KKK22132.1 - 0.0012 19.2 0.2 0.0054 17.1 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KKK22132.1 - 0.0014 17.8 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KKK22132.1 - 0.0014 18.0 0.1 0.0029 16.9 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 KKK22132.1 - 0.004 17.5 0.1 0.0083 16.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KKK22132.1 - 0.013 14.9 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF2235 PF09994.4 KKK22133.1 - 1.9e-93 312.8 0.0 2.6e-93 312.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Coiled-coil_56 PF09813.4 KKK22134.1 - 0.27 11.2 3.7 0.4 10.6 1.3 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 OCD_Mu_crystall PF02423.10 KKK22135.1 - 1.4e-12 46.9 0.0 4.6e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KKK22135.1 - 0.0034 17.4 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Proteasome_A_N PF10584.4 KKK22135.1 - 0.095 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Pro_dh PF01619.13 KKK22136.1 - 4.5e-33 114.5 0.3 5.6e-33 114.2 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AA_permease PF00324.16 KKK22137.1 - 9.5e-127 423.2 46.6 1.2e-126 422.9 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK22137.1 - 1.1e-30 106.5 51.9 1.4e-30 106.2 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.17 KKK22138.1 - 4.5e-109 364.8 0.1 5.5e-109 364.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4322 PF14210.1 KKK22138.1 - 0.18 11.2 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4322) MARVEL PF01284.18 KKK22139.1 - 2.5e-09 37.0 7.5 3.6e-09 36.5 5.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain SecG PF03840.9 KKK22139.1 - 0.011 15.4 0.2 0.94 9.2 0.0 3.2 3 0 0 3 3 3 0 Preprotein translocase SecG subunit Choline_transpo PF04515.7 KKK22139.1 - 0.066 11.9 5.1 0.13 10.9 3.6 1.5 1 1 0 1 1 1 0 Plasma-membrane choline transporter DUF4013 PF13197.1 KKK22139.1 - 0.3 10.4 8.6 0.22 10.8 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) Sulfatase PF00884.18 KKK22144.1 - 8.9e-75 251.7 0.0 1.1e-74 251.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF498 PF04430.9 KKK22148.1 - 9.5e-28 95.9 0.0 1.3e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.15 KKK22149.1 - 7.6e-101 337.8 0.0 1.2e-100 337.2 0.0 1.3 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KKK22149.1 - 0.0024 17.3 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 KKK22149.1 - 0.031 14.0 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF754 PF05449.6 KKK22149.1 - 0.083 12.9 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF754) ABC_tran PF00005.22 KKK22150.1 - 1.2e-33 116.2 0.0 2.9e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KKK22150.1 - 4.8e-31 108.1 10.9 4.8e-31 108.1 7.5 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KKK22150.1 - 4.3e-07 29.3 0.6 1.7e-05 24.1 0.1 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK22150.1 - 8.7e-05 22.6 0.0 0.081 12.8 0.0 2.3 1 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KKK22150.1 - 0.0038 17.1 0.2 0.061 13.2 0.2 2.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KKK22150.1 - 0.0064 16.4 0.5 0.024 14.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KKK22150.1 - 0.0086 15.5 0.2 0.021 14.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK22150.1 - 0.0094 16.0 0.1 0.083 13.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KKK22150.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KKK22150.1 - 0.11 12.2 0.1 0.81 9.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_16 PF00722.16 KKK22151.1 - 5.2e-41 139.9 7.6 5.2e-41 139.9 5.3 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 OHCU_decarbox PF09349.5 KKK22165.1 - 2.5e-42 144.8 0.0 4.1e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 OHCU decarboxylase WD40 PF00400.27 KKK22165.1 - 3e-31 106.1 8.3 2.3e-07 30.4 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KKK22165.1 - 0.0063 16.2 0.0 6.9 6.4 0.0 3.7 4 2 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Fn3-like PF14310.1 KKK22169.1 - 1.6e-25 88.7 0.7 7.6e-23 80.2 0.0 2.2 2 0 0 2 2 2 2 Fibronectin type III-like domain Nup54 PF13874.1 KKK22170.1 - 5.2e-45 152.5 0.6 1.5e-44 151.0 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KKK22170.1 - 1.5e-08 34.8 95.6 1.5e-07 31.6 39.9 2.8 1 1 1 2 2 2 2 Nucleoporin FG repeat region NBP1 PF08537.5 KKK22170.1 - 1.6 7.8 6.6 2.9 7.0 4.6 1.4 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 Tom5 PF10642.4 KKK22171.1 - 6.4e-22 76.9 0.2 6.8e-22 76.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.6 KKK22172.1 - 1.6e-13 49.9 0.0 2.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CHCH PF06747.8 KKK22173.1 - 1.8e-06 27.6 4.5 1.8e-06 27.6 3.1 2.5 3 0 0 3 3 3 2 CHCH domain Pet191_N PF10203.4 KKK22173.1 - 0.067 13.2 10.0 3.6 7.6 4.7 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KKK22173.1 - 0.53 10.0 14.7 1.2 8.9 3.0 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 KKK22173.1 - 1 9.4 9.8 4.9 7.2 0.4 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb MCM PF00493.18 KKK22174.1 - 1.5e-131 438.1 0.1 2.3e-131 437.5 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KKK22174.1 - 4.8e-19 69.0 0.1 4.8e-19 69.0 0.1 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KKK22174.1 - 2.4e-05 23.5 0.0 0.00025 20.2 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KKK22174.1 - 0.0029 17.0 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 KKK22174.1 - 0.0031 17.2 0.0 0.0086 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK22174.1 - 0.0052 16.3 0.0 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DLH PF01738.13 KKK22176.1 - 1.5e-09 37.4 0.0 1.9e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family cobW PF02492.14 KKK22177.1 - 4.6e-34 117.3 0.0 5.6e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KKK22177.1 - 5.9e-06 25.2 1.3 0.00011 21.1 0.9 2.0 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 KKK22177.1 - 0.0057 16.5 0.0 0.01 15.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KKK22177.1 - 0.006 17.3 0.0 0.0098 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK22177.1 - 0.0086 16.3 0.0 0.015 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KKK22177.1 - 0.02 13.6 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 KKK22177.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 KKK22177.1 - 0.03 13.7 0.0 2.8 7.3 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.12 KKK22177.1 - 0.038 13.4 0.0 0.095 12.1 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.18 KKK22177.1 - 0.042 13.2 0.1 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.13 KKK22177.1 - 0.073 12.6 0.0 0.27 10.7 0.0 1.8 1 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 KKK22177.1 - 0.082 11.9 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 KKK22177.1 - 0.093 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 KKK22177.1 - 0.15 11.7 0.0 0.99 9.1 0.0 2.2 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 KKK22177.1 - 0.15 11.0 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MFS_1 PF07690.11 KKK22182.1 - 4.2e-41 140.8 35.0 4.2e-41 140.8 24.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK22182.1 - 1.3e-10 40.4 9.2 1.3e-10 40.4 6.4 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter DUF2235 PF09994.4 KKK22183.1 - 2.9e-53 181.0 0.3 1.2e-40 139.7 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KKK22183.1 - 0.012 15.3 0.0 0.034 13.9 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Sulfatase PF00884.18 KKK22184.1 - 1.8e-65 221.1 1.1 2.3e-65 220.8 0.7 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KKK22184.1 - 0.036 13.4 6.3 2.1 7.5 4.4 2.5 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase MAPEG PF01124.13 KKK22185.1 - 5.9e-20 71.1 0.3 6.8e-20 70.9 0.2 1.0 1 0 0 1 1 1 1 MAPEG family DUF1191 PF06697.7 KKK22186.1 - 0.0019 17.0 0.1 0.0081 15.0 0.0 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1191) DUF4448 PF14610.1 KKK22186.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 KKK22186.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KKK22186.1 - 0.27 10.9 6.5 0.75 9.4 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family RAP1 PF07218.6 KKK22186.1 - 4.1 5.3 6.0 5.6 4.9 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Metallophos PF00149.23 KKK22187.1 - 1.1e-42 145.7 1.4 1.9e-42 144.9 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KKK22187.1 - 1.1e-15 57.4 0.2 4.9e-15 55.3 0.1 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KKK22187.1 - 2.8e-10 39.3 0.4 4.7e-08 32.0 0.2 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.2 KKK22187.1 - 0.0057 16.5 0.1 0.037 13.8 0.0 2.4 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF3533 PF12051.3 KKK22188.1 - 2.1e-102 342.7 12.0 2.8e-102 342.3 8.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF2417 PF10329.4 KKK22188.1 - 0.0087 15.4 3.0 1.4 8.2 0.9 2.4 2 0 0 2 2 2 2 Region of unknown function (DUF2417) Aldo_ket_red PF00248.16 KKK22189.1 - 4.5e-53 179.9 0.0 5.1e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Caps_synth PF05704.7 KKK22190.1 - 2.7e-08 33.2 0.0 7.6e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KKK22190.1 - 0.0028 18.0 0.0 0.0068 16.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4044 PF13253.1 KKK22190.1 - 0.19 10.8 0.1 0.6 9.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) A_deaminase PF00962.17 KKK22192.1 - 7.9e-39 133.4 0.0 1.1e-37 129.7 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase KdpA PF03814.10 KKK22192.1 - 0.054 11.5 0.0 0.076 11.0 0.0 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit BatA PF07584.6 KKK22194.1 - 0.54 10.4 3.4 18 5.6 0.1 2.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal CorA PF01544.13 KKK22195.1 - 0.00043 19.3 0.8 0.00083 18.4 0.6 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein But2 PF09792.4 KKK22196.1 - 0.0026 17.5 1.7 0.0036 17.0 1.0 1.4 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF1635 PF07795.6 KKK22196.1 - 0.089 12.1 0.3 0.12 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Phosphoesterase PF04185.9 KKK22197.1 - 3.5e-37 128.4 6.3 3.5e-37 128.4 4.3 1.6 2 0 0 2 2 2 1 Phosphoesterase family Jacalin PF01419.12 KKK22198.1 - 0.00047 20.0 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Cu-oxidase_3 PF07732.10 KKK22199.1 - 3e-48 162.4 2.7 6.5e-47 158.1 0.1 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK22199.1 - 2.1e-39 134.1 7.5 8.3e-37 125.7 0.7 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK22199.1 - 7.7e-38 129.8 0.6 3e-37 127.9 0.2 2.2 2 0 0 2 2 2 1 Multicopper oxidase Sld5 PF05916.6 KKK22218.1 - 2.3e-11 43.9 0.6 4.7e-11 42.9 0.4 1.5 1 0 0 1 1 1 1 GINS complex protein FlaF PF07309.6 KKK22218.1 - 0.059 13.2 1.9 0.099 12.5 1.3 1.3 1 0 0 1 1 1 0 Flagellar protein FlaF Mlf1IP PF10248.4 KKK22218.1 - 0.33 10.5 2.6 0.98 9.0 0.1 2.1 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein ATG16 PF08614.6 KKK22218.1 - 0.34 10.7 4.3 0.1 12.4 0.8 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MSA-2c PF12238.3 KKK22218.1 - 1.7 8.2 4.4 13 5.4 0.2 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c Rhodanese PF00581.15 KKK22219.1 - 7.2e-13 48.8 0.0 1.8e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-DNL PF05180.7 KKK22220.1 - 1.6e-30 104.5 0.4 2.7e-30 103.8 0.3 1.4 1 0 0 1 1 1 1 DNL zinc finger DUF2039 PF10217.4 KKK22220.1 - 0.0041 17.1 0.3 0.007 16.3 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Elf1 PF05129.8 KKK22220.1 - 0.01 15.5 0.8 0.019 14.6 0.5 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-CSL PF05207.8 KKK22220.1 - 0.015 14.8 0.6 0.028 13.9 0.4 1.4 1 0 0 1 1 1 0 CSL zinc finger E7 PF00527.13 KKK22220.1 - 0.03 14.4 5.6 0.15 12.2 3.9 2.1 1 1 1 2 2 2 0 E7 protein, Early protein zinc_ribbon_4 PF13717.1 KKK22220.1 - 0.036 13.7 1.0 0.15 11.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KKK22220.1 - 0.045 13.3 0.9 0.2 11.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 KKK22220.1 - 0.13 11.9 1.9 0.36 10.5 1.3 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 KKK22220.1 - 4.6 6.9 7.1 11 5.7 0.0 2.8 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 KKK22220.1 - 5.6 6.8 7.0 16 5.4 0.7 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cullin PF00888.17 KKK22221.1 - 2.8e-125 419.1 12.0 3.7e-125 418.7 8.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KKK22221.1 - 4.7e-27 93.5 0.3 2e-26 91.6 0.2 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain CwfJ_C_2 PF04676.9 KKK22222.1 - 1.1e-22 80.2 0.0 2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 KKK22222.1 - 7.2e-10 38.5 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DRIM PF07539.7 KKK22223.1 - 6e-46 155.3 0.0 2.5e-45 153.3 0.0 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 KKK22223.1 - 0.0016 18.3 4.7 2.2 8.5 0.0 7.0 9 0 0 9 9 9 1 HEAT repeat Corona_S2 PF01601.11 KKK22224.1 - 0.0088 14.1 7.1 0.012 13.7 4.9 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Prominin PF05478.6 KKK22224.1 - 2.6 5.4 13.4 3.3 5.1 9.3 1.0 1 0 0 1 1 1 0 Prominin DNA_pol_phi PF04931.8 KKK22225.1 - 3.2e-66 223.6 26.9 4.9e-64 216.4 18.6 2.5 1 1 0 1 1 1 1 DNA polymerase phi Apo-CII PF05355.6 KKK22225.1 - 0.033 14.0 0.2 0.14 12.0 0.1 2.2 1 0 0 1 1 1 0 Apolipoprotein C-II Nop14 PF04147.7 KKK22225.1 - 0.035 12.0 17.9 0.068 11.0 12.4 1.5 1 0 0 1 1 1 0 Nop14-like family DUF3510 PF12022.3 KKK22225.1 - 0.051 13.6 1.8 4.2 7.5 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) RRM_6 PF14259.1 KKK22226.1 - 0.0027 17.6 0.0 0.0069 16.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAP59_mtransfer PF11735.3 KKK22227.1 - 2.3e-81 272.5 0.0 3.2e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HSP90 PF00183.13 KKK22228.1 - 2.1e-254 844.8 36.4 2.4e-254 844.6 25.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KKK22228.1 - 1e-10 41.2 0.0 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KKK22228.1 - 1.5e-10 40.8 0.1 1.5e-10 40.8 0.1 2.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 KKK22228.1 - 0.064 13.5 0.4 0.064 13.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) LOH1CR12 PF10158.4 KKK22228.1 - 0.14 11.9 3.0 0.14 11.9 0.1 2.4 3 0 0 3 3 3 0 Tumour suppressor protein NTF2 PF02136.15 KKK22229.1 - 2.5e-26 92.3 0.5 4.5e-26 91.5 0.4 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KKK22229.1 - 3.3e-09 36.2 0.1 5.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK22229.1 - 1.4e-06 28.0 0.0 2.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK22229.1 - 5.5e-06 26.2 0.0 9.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Imm16 PF15565.1 KKK22229.1 - 0.026 14.3 0.4 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 16 RRM_3 PF08777.6 KKK22229.1 - 0.046 13.5 0.5 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Pkinase PF00069.20 KKK22232.1 - 6.5e-67 225.4 0.0 2.7e-66 223.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22232.1 - 9.4e-28 96.9 0.0 2e-27 95.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KKK22232.1 - 4.1e-05 22.7 0.0 0.00014 20.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK22232.1 - 0.00055 19.7 0.0 0.0019 17.9 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KKK22232.1 - 0.017 14.1 0.0 0.08 11.8 0.0 1.8 1 1 0 2 2 2 0 Kinase-like RIO1 PF01163.17 KKK22232.1 - 0.058 12.7 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family LEA_6 PF10714.4 KKK22232.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Avl9 PF09794.4 KKK22233.1 - 2.5e-139 463.9 0.1 9.3e-123 409.4 0.0 2.3 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 KKK22233.1 - 5e-10 39.0 0.1 3.2e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 KKK22233.1 - 0.013 14.8 0.3 0.013 14.8 0.2 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2347) zf-RING_2 PF13639.1 KKK22234.1 - 3.5e-09 36.3 4.1 5.9e-09 35.6 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KKK22234.1 - 9.4e-08 31.9 4.1 1.5e-07 31.3 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK22234.1 - 1.6e-07 30.8 1.8 2.4e-07 30.2 1.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK22234.1 - 2.7e-07 30.1 2.7 4.3e-07 29.4 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK22234.1 - 9.7e-06 25.6 4.2 2.7e-05 24.2 2.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KKK22234.1 - 0.075 12.7 1.8 0.13 12.0 1.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-MIZ PF02891.15 KKK22234.1 - 0.11 11.9 2.5 0.21 11.1 1.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 KKK22234.1 - 0.12 12.3 4.5 0.21 11.5 3.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2410 PF10307.4 KKK22235.1 - 9.6e-86 286.2 0.0 1.3e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Drc1-Sld2 PF11719.3 KKK22236.1 - 9.8e-135 449.9 22.7 1.4e-134 449.3 15.7 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein Suc_Fer-like PF06999.7 KKK22236.1 - 3e-42 145.2 1.8 3.5e-42 145.0 0.0 2.1 2 0 0 2 2 2 1 Sucrase/ferredoxin-like Zn_clus PF00172.13 KKK22237.1 - 4.6e-10 39.2 8.7 7.5e-10 38.5 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VIT1 PF01988.14 KKK22238.1 - 3.7e-60 203.0 3.6 4.5e-60 202.7 2.5 1.1 1 0 0 1 1 1 1 VIT family Phosphoesterase PF04185.9 KKK22239.1 - 2.3e-53 181.7 6.5 1.3e-52 179.2 4.5 2.0 1 1 0 1 1 1 1 Phosphoesterase family SKG6 PF08693.5 KKK22241.1 - 0.07 12.4 3.2 0.23 10.8 2.2 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain AF-4 PF05110.8 KKK22241.1 - 0.77 7.5 10.2 0.91 7.3 7.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AP_endonuc_2 PF01261.19 KKK22242.1 - 3.8e-13 49.2 0.3 7e-13 48.3 0.2 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel DSPc PF00782.15 KKK22245.1 - 0.0018 17.8 0.0 0.0024 17.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain BDHCT PF08072.6 KKK22245.1 - 0.12 12.5 0.1 0.68 10.0 0.1 2.1 2 0 0 2 2 2 0 BDHCT (NUC031) domain Zn_clus PF00172.13 KKK22246.1 - 7e-08 32.2 10.7 1.3e-07 31.4 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK22246.1 - 2.9e-07 29.6 1.7 4.9e-07 28.8 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 KKK22249.1 - 5.5e-17 62.0 1.9 8.7e-17 61.3 1.3 1.2 1 0 0 1 1 1 1 RTA1 like protein adh_short_C2 PF13561.1 KKK22250.1 - 2.3e-15 57.0 0.0 2.5e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK22250.1 - 3.7e-15 56.2 0.4 5.5e-15 55.6 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK22250.1 - 9e-06 25.4 0.2 1.5e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KKK22250.1 - 0.023 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aa_trans PF01490.13 KKK22251.1 - 9.6e-62 208.7 19.4 9.2e-54 182.4 9.5 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Claudin_2 PF13903.1 KKK22251.1 - 0.4 10.3 12.2 0.53 9.9 0.5 2.8 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Zn_clus PF00172.13 KKK22252.1 - 1.9e-09 37.2 12.4 3.1e-09 36.5 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pectinesterase PF01095.14 KKK22253.1 - 4.8e-53 179.6 5.7 6.1e-53 179.3 3.9 1.0 1 0 0 1 1 1 1 Pectinesterase AA_permease_2 PF13520.1 KKK22254.1 - 5.7e-48 163.5 43.5 7.1e-48 163.1 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK22254.1 - 1.3e-23 83.0 39.0 1.8e-23 82.6 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease PTR2 PF00854.16 KKK22255.1 - 1.1e-27 96.8 0.4 1.9e-26 92.7 0.3 2.1 1 1 0 1 1 1 1 POT family ketoacyl-synt PF00109.21 KKK22256.1 - 1.6e-71 240.7 0.0 1.8e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 KKK22256.1 - 1.2e-06 27.7 0.1 1.7e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KKK22256.1 - 0.00022 20.8 2.0 0.00047 19.7 1.4 1.7 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.20 KKK22257.1 - 4.2e-20 72.3 3.9 7e-20 71.5 2.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK22257.1 - 9e-19 68.1 0.2 2.1e-18 66.9 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK22257.1 - 3.5e-07 30.0 1.8 7.4e-07 29.0 1.3 1.4 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.1 KKK22257.1 - 0.034 14.3 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ldh_1_N PF00056.18 KKK22257.1 - 0.11 12.2 0.1 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KKK22258.1 - 2.3e-27 95.9 0.1 8.7e-16 57.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK22258.1 - 3.8e-07 29.3 4.1 0.00029 19.8 1.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KKK22258.1 - 6.2e-07 28.8 1.0 0.011 14.8 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KKK22258.1 - 3.2e-06 27.0 1.1 3.2e-05 23.8 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KKK22258.1 - 1.6e-05 23.9 1.0 2.8e-05 23.1 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KKK22258.1 - 9e-05 22.6 0.5 0.0012 18.9 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK22258.1 - 0.00035 20.9 1.7 0.0076 16.6 0.3 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK22258.1 - 0.00047 20.0 0.4 0.00092 19.1 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK22258.1 - 0.00092 18.2 0.5 1.1 8.1 0.3 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 KKK22258.1 - 0.0049 15.9 0.3 0.0089 15.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KKK22258.1 - 0.0069 14.9 0.3 0.012 14.0 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KKK22258.1 - 0.0099 14.7 1.4 0.015 14.2 1.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KKK22258.1 - 0.011 15.3 0.4 0.018 14.5 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 KKK22258.1 - 0.063 11.9 2.3 0.31 9.6 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KKK22258.1 - 0.13 12.0 1.4 8.1 6.2 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding zf-C2H2 PF00096.21 KKK22261.1 - 3.9e-07 30.0 15.5 0.0027 17.9 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK22261.1 - 1.9e-05 24.7 11.9 2e-05 24.6 0.6 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK22261.1 - 0.019 15.2 13.4 0.083 13.2 1.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 KKK22261.1 - 0.17 12.1 4.1 0.36 11.1 1.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KKK22261.1 - 0.19 11.7 1.9 3.3 7.7 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 KKK22261.1 - 0.35 10.6 11.6 0.76 9.5 2.2 2.5 1 1 1 2 2 2 0 BED zinc finger FAD_binding_4 PF01565.18 KKK22263.1 - 5.6e-17 61.5 0.1 1.3e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK22263.1 - 6.8e-09 35.4 0.1 1.9e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KKK22263.1 - 0.0094 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Pro-kuma_activ PF09286.6 KKK22264.1 - 4.8e-30 104.4 0.4 1.1e-28 100.0 0.0 2.6 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KKK22264.1 - 1.7e-06 27.4 0.0 3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Subtilase family GPI-anchored PF10342.4 KKK22265.1 - 3.8e-20 72.1 3.9 3.8e-20 72.1 2.7 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1593 PF07632.6 KKK22266.1 - 1.5e-79 267.0 0.1 2.5e-79 266.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) ArabFuran-catal PF09206.6 KKK22267.1 - 5.9e-149 495.3 18.2 5.9e-149 495.3 12.6 1.5 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 KKK22267.1 - 2.2e-64 215.4 3.6 3.3e-64 214.9 2.5 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) Pyr_redox_3 PF13738.1 KKK22268.1 - 8e-22 78.3 0.0 1.6e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK22268.1 - 3.1e-16 58.6 0.0 1.5e-14 53.1 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK22268.1 - 2e-09 37.3 0.4 6.6e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KKK22268.1 - 2.1e-06 26.9 0.0 0.0001 21.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KKK22268.1 - 0.032 14.0 0.6 0.69 9.6 0.0 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding mRNA_cap_C PF03919.10 KKK22268.1 - 0.046 14.0 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain DAO PF01266.19 KKK22268.1 - 0.066 12.1 0.0 0.22 10.3 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KKK22268.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF877 PF05943.7 KKK22268.1 - 0.14 10.6 0.1 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF877) CVNH PF08881.5 KKK22269.1 - 4e-31 107.3 0.9 5.6e-31 106.8 0.6 1.2 1 0 0 1 1 1 1 CVNH domain Rick_17kDa_Anti PF05433.10 KKK22269.1 - 8.3e-06 25.3 13.9 1.3e-05 24.7 9.6 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 KKK22269.1 - 0.00074 19.1 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain TraT PF05818.7 KKK22269.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Gly-zipper_Omp PF13488.1 KKK22269.1 - 0.0027 17.3 9.5 0.0044 16.6 6.6 1.3 1 0 0 1 1 1 1 Glycine zipper DUF2076 PF09849.4 KKK22269.1 - 0.0031 17.6 0.7 0.0045 17.0 0.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF533 PF04391.7 KKK22269.1 - 0.0056 16.0 0.1 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF533) FAP PF07174.6 KKK22269.1 - 0.052 12.8 9.9 0.078 12.2 6.8 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Gly-zipper_YMGG PF13441.1 KKK22269.1 - 0.11 11.9 13.4 0.19 11.2 9.3 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Transgly_assoc PF04226.8 KKK22269.1 - 0.92 9.6 10.4 1.4 9.0 7.2 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein DUF2370 PF10176.4 KKK22269.1 - 2.4 7.4 4.7 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) MFS_1 PF07690.11 KKK22271.1 - 1.1e-10 40.8 46.9 3e-10 39.3 28.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK22271.1 - 3.7e-09 35.3 10.6 3.7e-09 35.3 7.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4225 PF13988.1 KKK22271.1 - 3.9 6.9 5.9 0.67 9.4 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) DUF3439 PF11921.3 KKK22271.1 - 6.7 6.4 9.4 15 5.3 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Abhydrolase_3 PF07859.8 KKK22272.1 - 9.1e-47 159.3 0.1 1.2e-46 158.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KKK22272.1 - 1.3e-05 25.5 0.0 1.8e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KKK22272.1 - 6.2e-05 22.7 0.1 8.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK22272.1 - 0.0009 19.1 0.6 0.0016 18.3 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KKK22272.1 - 0.0013 17.4 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 KKK22272.1 - 0.13 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Dabb PF07876.7 KKK22273.1 - 1.2e-08 35.2 0.0 1.7e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Acyl_transf_1 PF00698.16 KKK22274.1 - 1.1e-80 271.3 0.7 7.5e-76 255.4 0.0 3.2 2 1 1 3 3 3 2 Acyl transferase domain DUF1729 PF08354.5 KKK22274.1 - 4.7e-29 99.9 0.0 2e-28 97.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 KKK22274.1 - 2.7e-27 94.5 0.0 6.2e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KKK22274.1 - 1.1e-10 41.4 0.1 1.1e-09 38.1 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KKK22274.1 - 0.086 11.9 0.0 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase ketoacyl-synt PF00109.21 KKK22275.1 - 3.5e-25 88.9 0.2 8.6e-25 87.6 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KKK22275.1 - 1.1e-16 61.3 0.0 2.2e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 KKK22275.1 - 1e-12 47.9 0.0 2.9e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 KKK22275.1 - 7.1e-12 45.1 0.0 2.1e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.20 KKK22275.1 - 1.8e-08 34.4 0.5 5.8e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK22275.1 - 7.3e-06 25.7 0.0 3.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KKK22276.1 - 4e-12 46.3 0.5 2.1e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KKK22276.1 - 0.059 13.0 2.7 1.3 8.6 0.7 3.1 2 1 0 2 2 2 0 KR domain Eno-Rase_NADH_b PF12242.3 KKK22276.1 - 0.32 10.7 2.3 1 9.1 1.3 2.0 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 KKK22277.1 - 9.3e-63 212.3 0.0 1.2e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1772 PF08592.6 KKK22278.1 - 7.7e-24 84.0 3.7 9.2e-24 83.7 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Sulfate_transp PF00916.15 KKK22278.1 - 0.02 13.9 1.5 0.022 13.8 1.1 1.1 1 0 0 1 1 1 0 Sulfate transporter family DUF1049 PF06305.6 KKK22278.1 - 0.068 12.6 1.3 4.1 6.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Gemini_AC4_5_2 PF08464.5 KKK22278.1 - 0.079 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region p450 PF00067.17 KKK22279.1 - 6.5e-59 199.6 0.0 2e-56 191.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 NAD_binding_10 PF13460.1 KKK22280.1 - 7.2e-10 39.1 0.0 4.6e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KKK22280.1 - 6.8e-06 25.5 0.0 2.5e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 KKK22280.1 - 0.0051 17.1 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KKK22280.1 - 0.0082 15.0 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KKK22280.1 - 0.078 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GMC_oxred_N PF00732.14 KKK22281.1 - 2.3e-52 177.9 0.0 3.1e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK22281.1 - 3.7e-35 121.3 0.0 6e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KKK22281.1 - 1.4e-08 34.0 0.0 5.7e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK22281.1 - 4e-07 29.2 1.5 6.3e-05 22.0 0.9 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KKK22281.1 - 6.9e-05 22.9 0.0 0.0079 16.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK22281.1 - 0.00015 21.7 0.1 0.00038 20.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK22281.1 - 0.002 17.2 0.1 0.43 9.6 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.7 KKK22281.1 - 0.0026 16.7 0.2 0.0044 15.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KKK22281.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KKK22281.1 - 0.026 13.5 0.2 0.049 12.6 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KKK22281.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KKK22281.1 - 0.035 12.7 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 KKK22281.1 - 0.063 13.6 2.1 0.84 10.0 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KKK22281.1 - 0.19 11.7 0.4 0.44 10.5 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain DUF4243 PF14027.1 KKK22282.1 - 2.5e-92 309.8 0.0 3e-92 309.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF433 PF04255.9 KKK22282.1 - 0.077 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) DUF2172 PF09940.4 KKK22283.1 - 0.033 12.5 0.0 0.064 11.6 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2172) FAD_binding_4 PF01565.18 KKK22284.1 - 1.2e-16 60.4 1.8 2.5e-16 59.4 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK22284.1 - 5.8e-07 29.3 0.0 1.7e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_2 PF00891.13 KKK22285.1 - 4.3e-30 104.6 0.1 9.4e-30 103.5 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase NAD_binding_10 PF13460.1 KKK22285.1 - 1.4e-16 61.0 0.1 2.2e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK22285.1 - 4.8e-07 29.4 0.0 8.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KKK22285.1 - 9.4e-07 28.3 0.1 1.9e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family Methyltransf_23 PF13489.1 KKK22285.1 - 0.00042 20.0 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KKK22285.1 - 0.00047 18.9 0.0 0.00068 18.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KKK22285.1 - 0.0089 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Dimerisation PF08100.6 KKK22285.1 - 0.011 15.5 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain AflR PF08493.5 KKK22286.1 - 7.4e-122 405.6 13.7 1.5e-121 404.6 9.0 1.8 1 1 0 1 1 1 1 Aflatoxin regulatory protein DUF1510 PF07423.6 KKK22286.1 - 0.0038 16.6 15.7 0.0057 16.0 10.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 KKK22286.1 - 0.0072 15.7 17.7 0.011 15.2 12.2 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Ycf1 PF05758.7 KKK22286.1 - 0.024 12.3 9.5 0.03 12.0 6.6 1.0 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 KKK22286.1 - 0.046 12.3 8.3 0.059 12.0 5.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RIC3 PF15361.1 KKK22286.1 - 0.081 13.1 13.1 0.17 12.1 9.1 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 MMR1 PF08505.5 KKK22286.1 - 0.082 12.9 18.5 0.14 12.1 12.8 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4045 PF13254.1 KKK22286.1 - 0.12 11.6 14.1 0.17 11.1 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TP53IP5 PF15331.1 KKK22286.1 - 0.14 12.0 7.9 0.21 11.4 5.5 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 FLO_LFY PF01698.11 KKK22286.1 - 0.14 10.9 15.0 0.2 10.4 10.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Daxx PF03344.10 KKK22286.1 - 0.19 10.2 17.6 0.25 9.7 12.2 1.1 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 KKK22286.1 - 0.3 10.9 15.2 0.48 10.2 10.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.9 KKK22286.1 - 0.32 10.5 8.6 0.64 9.5 5.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GAGA_bind PF06217.7 KKK22286.1 - 0.43 10.4 13.6 0.64 9.9 9.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 KKK22286.1 - 0.85 7.5 15.3 1.1 7.1 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Herpes_UL87 PF03043.9 KKK22286.1 - 1.1 7.5 3.9 1.6 7.0 2.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family PAT1 PF09770.4 KKK22286.1 - 1.2 7.3 39.6 1.5 6.9 27.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 KKK22286.1 - 2 6.0 17.1 2.7 5.5 11.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rtf2 PF04641.7 KKK22286.1 - 2.3 7.3 14.6 3.4 6.8 10.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Suf PF05843.9 KKK22286.1 - 4.2 7.0 19.8 3.8e+02 0.6 16.5 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DDHD PF02862.12 KKK22286.1 - 4.7 6.9 12.3 8.5 6.0 8.6 1.4 1 0 0 1 1 1 0 DDHD domain Med15 PF09606.5 KKK22286.1 - 6.9 4.7 53.8 9.8 4.2 37.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.12 KKK22286.1 - 7.5 5.2 8.9 12 4.6 6.2 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.11 KKK22286.1 - 8.3 6.2 12.4 17 5.1 8.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 KKK22286.1 - 8.4 6.0 11.5 14 5.3 7.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Peroxidase_2 PF01328.12 KKK22288.1 - 6.2e-43 146.6 0.0 8.2e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 DUF4267 PF14087.1 KKK22289.1 - 1.9e-32 111.1 3.8 3.8e-32 110.2 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) adh_short PF00106.20 KKK22289.1 - 3.6e-11 43.2 0.2 6.1e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK22289.1 - 0.00011 22.0 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK22289.1 - 0.0019 17.8 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK22289.1 - 0.0036 16.7 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2892 PF11127.3 KKK22289.1 - 9.9 6.0 8.2 1.2 9.0 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) ketoacyl-synt PF00109.21 KKK22290.1 - 2.3e-78 263.1 0.0 4.8e-78 262.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK22290.1 - 4.9e-44 150.9 0.0 1.1e-41 143.2 0.0 2.7 2 1 0 2 2 2 1 Acyl transferase domain Thioesterase PF00975.15 KKK22290.1 - 1.3e-36 126.9 0.0 4.7e-36 125.1 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 KKK22290.1 - 2.5e-33 114.4 0.1 6e-33 113.2 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KKK22290.1 - 1.8e-19 69.7 11.3 2.8e-11 43.4 0.5 2.8 3 0 0 3 3 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KKK22290.1 - 7.3e-15 54.8 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 KKK22290.1 - 1.9e-07 31.2 0.0 0.0023 17.8 0.0 3.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK22290.1 - 3.2e-06 26.9 0.0 0.016 14.9 0.0 2.9 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KKK22290.1 - 0.0016 17.4 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lipase_3 PF01764.20 KKK22290.1 - 0.16 11.6 0.0 21 4.6 0.0 2.4 2 0 0 2 2 2 0 Lipase (class 3) BSP_II PF05432.6 KKK22290.1 - 0.54 9.4 4.2 1 8.5 2.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) p450 PF00067.17 KKK22291.1 - 8.2e-56 189.4 0.0 1.1e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.6 KKK22292.1 - 2.9e-17 63.3 0.2 3.5e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 EthD domain p450 PF00067.17 KKK22293.1 - 8.4e-54 182.8 0.0 1.2e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 KKK22294.1 - 2.1e-61 207.2 0.0 3.1e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 KKK22294.1 - 4.5e-34 117.7 0.8 7.3e-34 117.0 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK22294.1 - 1.1e-26 94.1 0.0 2e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK22294.1 - 7.4e-18 64.8 0.5 1.6e-17 63.7 0.3 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK22294.1 - 0.00018 21.0 0.2 0.00031 20.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KKK22294.1 - 0.0097 16.4 0.2 0.032 14.8 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 KKK22294.1 - 0.045 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GST_C PF00043.20 KKK22295.1 - 2.2e-13 50.0 0.0 3.2e-13 49.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK22295.1 - 4.9e-11 42.6 0.0 1.7e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KKK22295.1 - 6e-10 39.2 0.0 1.4e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KKK22295.1 - 1.1e-06 29.0 0.0 1.9e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KKK22295.1 - 2e-06 27.6 0.0 5.4e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK22295.1 - 3e-06 27.0 0.0 6.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-BED PF02892.10 KKK22296.1 - 0.096 12.4 2.7 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 KKK22296.1 - 2.1 8.8 6.3 0.38 11.2 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KKK22303.1 - 0.00033 20.7 16.0 0.0072 16.5 1.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger ATP_sub_h PF10775.4 KKK22311.1 - 2.9e-26 90.9 0.3 5.1e-26 90.1 0.2 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KKK22311.1 - 0.00019 21.3 0.1 0.00038 20.3 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 STAT_bind PF02864.10 KKK22311.1 - 0.034 13.7 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 STAT protein, DNA binding domain DUF1765 PF08578.5 KKK22312.1 - 1.7e-44 150.9 6.1 3.5e-44 149.8 3.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) DUF3210 PF11489.3 KKK22313.1 - 8.3e-249 828.0 70.8 8.3e-249 828.0 49.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3210) TFIIB PF00382.14 KKK22314.1 - 5.4e-39 131.8 0.1 3.9e-19 68.2 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KKK22314.1 - 8e-10 37.8 1.0 8e-10 37.8 0.7 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding Sigma70_r4 PF04545.11 KKK22314.1 - 0.077 12.3 0.0 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.1 KKK22314.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain TPR_19 PF14559.1 KKK22315.1 - 9.7e-14 51.4 0.3 6.2e-05 23.2 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK22315.1 - 6.2e-09 36.2 0.0 0.0063 17.1 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 KKK22315.1 - 4.7e-05 23.7 4.0 0.054 13.8 0.3 2.3 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_2 PF07719.12 KKK22315.1 - 0.00015 21.4 0.1 0.27 11.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 KKK22315.1 - 0.0018 18.2 0.4 0.14 12.0 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK22315.1 - 0.0019 18.5 0.4 7.4 7.2 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK22315.1 - 0.002 17.7 0.0 0.25 11.0 0.0 2.9 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.1 KKK22315.1 - 0.022 15.3 0.3 13 6.7 0.0 3.5 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KKK22315.1 - 0.059 13.3 1.2 0.39 10.6 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KKK22315.1 - 0.11 11.7 0.5 0.6 9.2 0.1 1.9 2 0 0 2 2 2 0 Coatomer epsilon subunit NARP1 PF12569.3 KKK22315.1 - 0.18 10.4 0.1 0.32 9.6 0.0 1.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 SLT_L PF14718.1 KKK22315.1 - 0.25 11.1 2.6 4 7.3 0.2 2.8 2 2 0 2 2 2 0 Soluble lytic murein transglycosylase L domain TPR_10 PF13374.1 KKK22315.1 - 0.51 10.3 2.7 0.99 9.4 0.2 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat Cg6151-P PF10233.4 KKK22316.1 - 4.6e-43 145.7 15.1 5.6e-43 145.5 10.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.5 KKK22316.1 - 0.0021 17.7 13.7 0.003 17.2 9.5 1.2 1 0 0 1 1 1 1 COPI associated protein DUF599 PF04654.7 KKK22316.1 - 0.017 14.2 2.3 0.02 14.0 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF599 DUF2207 PF09972.4 KKK22316.1 - 0.04 12.4 5.3 0.051 12.1 3.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Viral_Beta_CD PF04530.7 KKK22316.1 - 0.43 10.7 2.8 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Viral Beta C/D like family YtpI PF14007.1 KKK22316.1 - 8.4 6.3 15.2 7.1 6.6 4.9 2.7 1 1 2 3 3 3 0 YtpI-like protein HlyIII PF03006.15 KKK22317.1 - 1e-62 211.4 11.5 1.2e-62 211.2 8.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related SAC3_GANP PF03399.11 KKK22318.1 - 2.1e-07 30.6 0.0 3.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KKK22318.1 - 0.0097 15.6 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF3024 PF11225.3 KKK22318.1 - 0.059 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) Pkinase PF00069.20 KKK22319.1 - 1.8e-59 201.0 0.0 2.3e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22319.1 - 1e-32 113.2 0.0 1.2e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK22319.1 - 0.0014 17.6 0.0 0.0024 16.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK22319.1 - 0.0081 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK22319.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KKK22319.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 KKK22319.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FUSC PF04632.7 KKK22320.1 - 0.09 11.2 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TFR_dimer PF04253.10 KKK22321.1 - 8.6e-35 119.0 0.1 1.5e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KKK22321.1 - 1.2e-13 51.2 0.0 2.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KKK22321.1 - 2e-06 27.4 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PA domain Sec1 PF00995.18 KKK22322.1 - 1.3e-128 430.1 0.0 1.4e-128 430.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SNARE PF05739.14 KKK22323.1 - 0.00085 18.9 3.5 0.00085 18.9 2.4 3.0 3 0 0 3 3 3 1 SNARE domain SF3b1 PF08920.5 KKK22324.1 - 3.2e-45 153.7 5.4 7.4e-44 149.3 3.7 2.5 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KKK22324.1 - 8.8e-15 54.7 4.1 0.011 15.9 0.0 7.8 6 3 4 10 10 10 5 HEAT repeats HEAT PF02985.17 KKK22324.1 - 1.2e-09 37.4 11.1 0.15 12.1 0.3 8.9 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 KKK22324.1 - 4.9e-09 36.4 6.3 0.55 10.8 0.0 7.7 6 2 2 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KKK22324.1 - 5.9e-06 26.5 0.6 0.8 10.1 0.0 5.2 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KKK22324.1 - 0.00025 19.5 0.5 0.54 8.5 0.0 3.4 2 2 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.3 KKK22324.1 - 0.0031 16.8 0.2 1.1 8.6 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.7 KKK22324.1 - 0.005 16.2 0.5 2.3 7.5 0.0 3.8 5 0 0 5 5 5 1 NUC173 domain Cnd1 PF12717.2 KKK22324.1 - 0.2 11.4 1.3 28 4.5 0.0 4.3 6 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 B56 PF01603.15 KKK22324.1 - 0.21 10.1 0.0 1.8 7.0 0.0 2.5 3 1 1 4 4 4 0 Protein phosphatase 2A regulatory B subunit (B56 family) Arm PF00514.18 KKK22324.1 - 0.3 10.9 1.4 74 3.3 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UQ_con PF00179.21 KKK22325.1 - 6.3e-27 93.7 0.0 7.3e-27 93.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK22325.1 - 4.4e-07 29.7 0.0 5.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KKK22325.1 - 7.3e-05 22.6 0.2 0.00011 22.1 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KKK22325.1 - 0.051 13.2 0.1 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.20 KKK22326.1 - 5.2e-62 209.3 0.0 6.7e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22326.1 - 6.4e-27 94.2 0.0 9.2e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK22326.1 - 0.0011 17.9 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK22326.1 - 0.011 14.7 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KKK22326.1 - 0.021 14.1 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Lipase_3 PF01764.20 KKK22327.1 - 3e-19 69.0 0.0 5.1e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KKK22327.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK22327.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 KKK22327.1 - 0.033 13.4 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Telomere_reg-2 PF10193.4 KKK22329.1 - 8e-37 125.9 0.0 2.1e-36 124.6 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein TLP-20 PF06088.6 KKK22329.1 - 0.16 11.6 1.4 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Ebola_NP PF05505.7 KKK22329.1 - 0.33 8.9 4.2 0.48 8.4 2.9 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein E2_bind PF08825.5 KKK22330.1 - 4e-30 103.4 0.1 6.1e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain ThiF PF00899.16 KKK22330.1 - 2.5e-22 79.1 0.2 4.7e-13 49.1 0.0 2.9 2 1 1 3 3 3 2 ThiF family UBACT PF02134.16 KKK22330.1 - 5.3e-22 77.1 1.0 9.9e-22 76.2 0.7 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KKK22330.1 - 2.6e-13 49.1 3.3 2.6e-13 49.1 2.3 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KKK22330.1 - 6.9e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 KKK22330.1 - 0.0005 20.1 0.2 0.0012 18.9 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Baculo_p74_N PF08404.5 KKK22330.1 - 0.1 11.3 0.3 0.18 10.5 0.2 1.3 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal RNA_pol_A_bac PF01000.21 KKK22331.1 - 8.3e-27 93.5 0.0 1.5e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KKK22331.1 - 1.9e-11 42.9 0.0 2.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 KKK22332.1 - 1.8e-132 440.4 0.0 2.3e-132 440.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KKK22332.1 - 0.04 12.6 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase IF-2B PF01008.12 KKK22333.1 - 2.7e-20 72.5 0.0 5.9e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 KKK22333.1 - 3.4e-06 26.7 0.0 6.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain adh_short_C2 PF13561.1 KKK22335.1 - 1.6e-23 83.7 0.0 1.9e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK22335.1 - 3.6e-15 56.2 0.0 4.6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK22335.1 - 1.5e-07 31.2 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK22335.1 - 0.014 14.8 0.1 0.023 14.1 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Dak1_2 PF13684.1 KKK22335.1 - 0.066 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Fungal_trans_2 PF11951.3 KKK22336.1 - 8.4e-07 27.9 0.2 1.2e-06 27.3 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Catalase PF00199.14 KKK22337.1 - 5.1e-185 614.6 1.4 6.1e-185 614.3 1.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KKK22337.1 - 1.5e-12 47.1 0.2 5.4e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive 120_Rick_ant PF12574.3 KKK22337.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Sugar_tr PF00083.19 KKK22338.1 - 9.6e-84 281.5 22.1 1.2e-83 281.2 15.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK22338.1 - 4.3e-15 55.2 35.0 8.5e-10 37.8 12.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ECH PF00378.15 KKK22339.1 - 4.3e-72 242.1 0.2 5.3e-72 241.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KKK22339.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 KKK22339.1 - 0.035 13.8 0.3 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S49 Rer1 PF03248.8 KKK22340.1 - 2.3e-81 271.5 6.0 2.6e-81 271.4 4.2 1.0 1 0 0 1 1 1 1 Rer1 family LtrA PF06772.6 KKK22341.1 - 1.2e-24 86.9 14.3 1.6e-24 86.5 9.9 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Lipase_3 PF01764.20 KKK22348.1 - 3.2e-06 26.7 0.0 7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KKK22348.1 - 0.041 13.6 0.0 0.081 12.6 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family VPS9 PF02204.13 KKK22349.1 - 9.9e-25 86.5 0.0 2.1e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Pkinase PF00069.20 KKK22350.1 - 6.8e-13 48.3 0.0 1.7e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22350.1 - 0.00077 18.6 0.0 0.35 9.8 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KKK22350.1 - 0.0012 17.8 0.2 0.21 10.4 0.1 2.5 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KKK22350.1 - 0.0036 17.0 0.1 0.0094 15.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Rieske PF00355.21 KKK22351.1 - 9.7e-10 37.9 0.0 1.9e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KKK22351.1 - 3.6e-05 23.4 0.0 6.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Ran_BP1 PF00638.13 KKK22352.1 - 2.4e-19 69.5 0.1 4.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain DEAD PF00270.24 KKK22353.1 - 1.8e-24 86.0 0.0 3.6e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK22353.1 - 9.9e-11 41.3 0.0 5.1e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 KKK22353.1 - 1.3e-09 38.5 0.4 2e-08 34.6 0.3 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1998) TFIIF_alpha PF05793.7 KKK22353.1 - 0.14 10.5 4.9 0.21 9.9 3.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NUC173 PF08161.7 KKK22353.1 - 0.21 10.9 0.0 0.45 9.8 0.0 1.5 1 0 0 1 1 1 0 NUC173 domain Fungal_trans_2 PF11951.3 KKK22354.1 - 9.2e-14 50.8 1.3 1.5e-13 50.1 0.9 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22354.1 - 1.1e-07 31.6 8.6 1.9e-07 30.8 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Formyl_trans_N PF00551.14 KKK22355.1 - 3.2e-35 121.3 0.0 3.8e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase PPR_2 PF13041.1 KKK22356.1 - 1.8e-24 85.4 1.7 1.3e-16 60.2 0.3 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KKK22356.1 - 4.4e-07 29.6 0.4 0.2 12.0 0.0 5.7 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 KKK22356.1 - 6.8e-07 28.8 1.8 0.22 11.5 0.2 4.2 4 0 0 4 4 4 3 PPR repeat PPR_1 PF12854.2 KKK22356.1 - 0.00033 20.0 0.2 0.49 9.9 0.0 3.6 3 0 0 3 3 3 2 PPR repeat Neur_chan_memb PF02932.11 KKK22356.1 - 0.18 11.6 0.1 0.52 10.1 0.1 1.8 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Yip1 PF04893.12 KKK22357.1 - 3e-14 52.8 13.3 4.8e-14 52.2 9.2 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KKK22357.1 - 0.68 9.5 9.2 1.3 8.6 6.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) zf-RING_2 PF13639.1 KKK22358.1 - 6.6e-14 51.4 5.5 1e-13 50.8 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KKK22358.1 - 1.2e-08 34.9 1.7 2.1e-08 34.1 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KKK22358.1 - 4.9e-08 32.5 4.4 7.5e-08 31.9 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK22358.1 - 3.9e-07 29.9 4.3 6.3e-07 29.3 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK22358.1 - 9.6e-06 25.2 2.9 1.5e-05 24.6 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK22358.1 - 0.00015 21.3 2.3 0.00024 20.6 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KKK22358.1 - 0.00033 20.6 5.9 0.0005 20.0 4.1 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 KKK22358.1 - 0.00044 20.0 2.1 0.00098 18.9 1.5 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KKK22358.1 - 0.018 14.5 2.1 0.04 13.4 1.0 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KKK22358.1 - 0.19 11.3 3.6 0.3 10.7 2.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KKK22358.1 - 0.22 11.2 2.5 0.47 10.2 1.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 KKK22358.1 - 0.24 11.4 2.6 0.41 10.6 1.8 1.3 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 KKK22358.1 - 0.26 11.2 3.3 0.49 10.3 2.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 KKK22358.1 - 0.64 9.7 4.8 0.47 10.2 2.2 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 KKK22358.1 - 2.3 7.9 3.9 3.7 7.3 2.7 1.3 1 0 0 1 1 1 0 PHD-finger ECM11 PF15463.1 KKK22359.1 - 4.5e-38 130.6 1.7 4.5e-38 130.6 1.2 3.1 3 0 0 3 3 3 1 Extracellular mutant protein 11 RNA_pol_I_TF PF04090.7 KKK22359.1 - 3.8e-12 45.8 0.0 2.6e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor NifU_N PF01592.11 KKK22361.1 - 1.1e-47 161.1 0.0 1.4e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain His_Phos_1 PF00300.17 KKK22363.1 - 2.3e-17 63.5 0.0 3.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L22 PF00237.14 KKK22364.1 - 5.8e-16 58.3 2.7 1.5e-14 53.8 0.1 2.7 2 1 0 2 2 2 1 Ribosomal protein L22p/L17e RRM_1 PF00076.17 KKK22365.1 - 1.9e-31 107.4 0.0 4.6e-12 45.3 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK22365.1 - 6.9e-27 93.2 0.2 1.1e-11 44.5 0.1 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK22365.1 - 4e-08 32.9 0.1 0.0097 15.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK22365.1 - 9.6e-07 28.4 0.0 0.012 15.4 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif AMP-binding PF00501.23 KKK22366.1 - 5.6e-92 308.2 0.0 6.7e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK22366.1 - 1.6e-16 61.0 0.0 5e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SET PF00856.23 KKK22367.1 - 2.9e-13 50.4 0.0 1.2e-11 45.1 0.0 2.5 1 1 0 1 1 1 1 SET domain DUF2052 PF09747.4 KKK22368.1 - 1.3e-35 122.9 10.5 4e-35 121.3 7.2 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Spermine_synth PF01564.12 KKK22369.1 - 4.5e-07 29.0 0.0 7.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_30 PF05430.6 KKK22369.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase SCIMP PF15050.1 KKK22399.1 - 0.017 15.0 3.6 0.27 11.1 0.0 3.1 3 0 0 3 3 3 0 SCIMP protein DUF3357 PF11837.3 KKK22399.1 - 0.53 10.1 2.9 0.74 9.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Sec61_beta PF03911.11 KKK22400.1 - 4.2e-19 68.0 0.7 5.4e-19 67.6 0.5 1.2 1 0 0 1 1 1 1 Sec61beta family SSF PF00474.12 KKK22401.1 - 6.1e-13 48.1 33.1 9e-11 41.0 12.1 2.5 3 0 0 3 3 3 2 Sodium:solute symporter family OTU PF02338.14 KKK22434.1 - 4e-17 62.9 3.6 1.5e-16 61.0 0.3 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KKK22434.1 - 1.4e-07 31.1 0.2 2.7e-05 23.6 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain adh_short PF00106.20 KKK22435.1 - 9.7e-27 93.9 0.0 1.3e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK22435.1 - 3.4e-26 92.5 0.0 4.1e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK22435.1 - 2.4e-08 33.8 0.0 3.6e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 KR domain Trehalase PF01204.13 KKK22436.1 - 6.5e-195 648.6 0.0 7.4e-195 648.4 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KKK22436.1 - 2e-07 30.2 0.1 3.2e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.16 KKK22437.1 - 1.2e-290 964.1 4.9 1.4e-290 963.9 3.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KKK22437.1 - 3.2e-12 46.2 0.1 1.2e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Aldedh PF00171.17 KKK22438.1 - 1.8e-63 214.5 0.0 1.9e-62 211.0 0.0 1.9 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Amidase PF01425.16 KKK22454.1 - 1.9e-100 336.8 0.0 2.2e-100 336.6 0.0 1.0 1 0 0 1 1 1 1 Amidase Rep_fac_C PF08542.6 KKK22455.1 - 2.8e-20 72.0 0.0 5.4e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KKK22455.1 - 6.9e-13 48.5 0.0 5.9e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KKK22455.1 - 1.9e-11 44.3 0.0 3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KKK22455.1 - 2.7e-07 30.5 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KKK22455.1 - 9.2e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KKK22455.1 - 1.9e-05 23.5 0.0 0.015 14.0 0.0 2.5 2 1 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KKK22455.1 - 2.2e-05 24.5 0.0 0.018 15.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK22455.1 - 2.4e-05 24.4 0.0 0.00048 20.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KKK22455.1 - 2.6e-05 23.3 0.0 8.1e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 KKK22455.1 - 0.00027 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 KKK22455.1 - 0.00052 19.5 0.0 0.00081 18.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 KKK22455.1 - 0.0012 18.3 0.0 0.11 11.9 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 KKK22455.1 - 0.0016 17.6 0.0 0.018 14.1 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KKK22455.1 - 0.002 17.8 0.0 0.0044 16.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KKK22455.1 - 0.0042 16.6 0.0 0.0076 15.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KKK22455.1 - 0.0067 16.1 0.2 0.056 13.1 0.1 2.3 1 1 1 2 2 2 1 NTPase DEAD PF00270.24 KKK22455.1 - 0.0095 15.4 0.2 0.36 10.3 0.0 2.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ArgK PF03308.11 KKK22455.1 - 0.017 13.9 0.0 0.033 12.9 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 KKK22455.1 - 0.043 13.2 0.0 0.18 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KKK22455.1 - 0.051 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KKK22455.1 - 0.057 13.7 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KKK22455.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KKK22455.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Porin_3 PF01459.17 KKK22457.1 - 1.2e-83 280.6 0.1 1.4e-83 280.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 KKK22457.1 - 0.0072 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term 6PF2K PF01591.13 KKK22458.1 - 1.1e-51 175.1 0.0 1.7e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KKK22458.1 - 2.8e-23 82.7 0.6 4.4e-23 82.1 0.4 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KKK22458.1 - 0.00015 21.6 0.0 0.00044 20.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK22458.1 - 0.0029 18.4 0.7 0.042 14.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KKK22458.1 - 0.034 13.8 0.0 0.44 10.1 0.0 2.3 1 1 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 KKK22459.1 - 3e-11 43.7 0.3 6.6e-10 39.4 0.1 2.8 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KKK22459.1 - 9.1e-08 32.3 0.3 6.9e-05 22.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KKK22459.1 - 0.15 11.1 0.0 3.3 6.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain IPPT PF01715.12 KKK22460.1 - 1.2e-43 148.9 0.1 2.3e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.3 KKK22460.1 - 1.2e-06 28.4 0.7 2.3e-06 27.5 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK22460.1 - 2.5e-06 27.4 0.6 4.6e-06 26.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_17 PF13207.1 KKK22460.1 - 1.8e-05 25.5 0.7 7.9e-05 23.4 0.1 2.6 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KKK22460.1 - 6.3e-05 22.8 0.9 0.0013 18.6 0.0 3.1 3 1 0 3 3 3 1 AAA domain IPT PF01745.11 KKK22460.1 - 0.0014 17.8 0.0 0.0036 16.5 0.0 1.7 1 0 0 1 1 1 1 Isopentenyl transferase AAA_25 PF13481.1 KKK22460.1 - 0.0015 17.9 0.0 0.015 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KKK22460.1 - 0.0059 16.9 2.7 0.043 14.1 0.4 3.2 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KKK22460.1 - 0.0088 16.0 0.0 0.052 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK22460.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AKAP95 PF04988.7 KKK22460.1 - 0.046 13.4 0.6 0.12 12.1 0.2 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF87 PF01935.12 KKK22460.1 - 0.048 13.4 0.3 0.72 9.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 zf-C2H2_2 PF12756.2 KKK22460.1 - 0.049 13.7 0.7 0.096 12.8 0.5 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_28 PF13521.1 KKK22460.1 - 0.083 12.8 0.9 0.4 10.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain PPV_E1_C PF00519.12 KKK22460.1 - 0.09 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase zf-C2H2 PF00096.21 KKK22460.1 - 0.14 12.5 0.2 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK22460.1 - 0.15 12.4 0.2 0.33 11.3 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger ABC_tran PF00005.22 KKK22460.1 - 0.22 11.8 2.0 0.37 11.0 0.2 2.6 2 1 0 2 2 1 0 ABC transporter Urm1 PF09138.6 KKK22461.1 - 3.6e-35 119.9 0.1 4.3e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KKK22461.1 - 0.0007 19.9 0.0 0.00093 19.5 0.0 1.3 1 0 0 1 1 1 1 ThiS family WD40 PF00400.27 KKK22462.1 - 2.9e-58 191.8 12.4 9.5e-08 31.6 0.0 12.6 13 0 0 13 13 13 10 WD domain, G-beta repeat BBS2_Mid PF14783.1 KKK22462.1 - 0.0018 18.0 0.0 37 4.1 0.0 5.3 6 0 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region RAI1 PF08652.6 KKK22463.1 - 5.8e-31 106.0 0.1 9.9e-31 105.3 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.8 KKK22464.1 - 7.9e-43 146.8 0.0 1e-42 146.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) MFS_1 PF07690.11 KKK22466.1 - 5.5e-15 54.9 40.8 8.1e-15 54.3 24.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Mon1 PF03164.9 KKK22467.1 - 5.3e-120 400.8 0.1 6.8e-120 400.4 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 zf-HIT PF04438.11 KKK22468.1 - 2.2e-09 36.8 12.0 3.5e-09 36.1 8.3 1.4 1 0 0 1 1 1 1 HIT zinc finger KRE9 PF05390.6 KKK22468.1 - 0.065 13.5 0.6 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 Ribosomal_60s PF00428.14 KKK22468.1 - 2.8 8.3 15.4 4 7.9 5.7 2.5 1 1 1 2 2 2 0 60s Acidic ribosomal protein Dopey_N PF04118.9 KKK22469.1 - 4e-116 387.1 0.0 1.6e-115 385.1 0.0 2.1 1 0 0 1 1 1 1 Dopey, N-terminal MazG PF03819.12 KKK22469.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Glyco_hydro_28 PF00295.12 KKK22506.1 - 2.6e-43 148.2 8.6 1.1e-41 142.9 4.5 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 YabP PF07873.6 KKK22506.1 - 0.21 11.2 0.9 1.4 8.5 0.0 2.7 3 0 0 3 3 3 0 YabP family adh_short PF00106.20 KKK22507.1 - 5.4e-23 81.7 0.6 2.2e-22 79.7 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK22507.1 - 8.2e-07 28.8 1.6 2.5e-05 24.0 1.0 2.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK22507.1 - 0.00045 20.0 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KKK22507.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding ABC2_membrane PF01061.19 KKK22508.1 - 2.6e-73 245.6 54.9 2.6e-40 137.8 18.7 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 KKK22508.1 - 1.5e-36 125.6 0.0 1.5e-17 64.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KKK22508.1 - 2e-26 91.6 1.1 7.8e-26 89.7 0.1 2.6 2 0 0 2 2 2 1 CDR ABC transporter Fungal_trans PF04082.13 KKK22508.1 - 4.6e-20 71.5 0.6 1e-19 70.4 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane_3 PF12698.2 KKK22508.1 - 9.7e-10 37.9 41.1 2.1e-05 23.7 9.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KKK22508.1 - 2.7e-08 33.4 1.2 0.0017 17.7 0.1 3.6 4 0 0 4 4 4 2 AAA domain Zn_clus PF00172.13 KKK22508.1 - 1.1e-06 28.4 7.1 2e-06 27.5 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_16 PF13191.1 KKK22508.1 - 1.8e-06 28.0 0.4 3.4e-05 23.8 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KKK22508.1 - 2.2e-05 24.5 0.7 0.14 12.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 KKK22508.1 - 3.8e-05 23.1 0.3 0.0034 16.8 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KKK22508.1 - 8.5e-05 21.7 0.0 0.005 16.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KKK22508.1 - 0.0013 18.6 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KKK22508.1 - 0.0021 17.5 0.1 1 8.7 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KKK22508.1 - 0.0026 17.2 0.1 1.8 7.9 0.1 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 KKK22508.1 - 0.0047 17.0 0.1 0.39 10.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 KKK22508.1 - 0.033 14.0 0.0 1 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KKK22508.1 - 0.037 14.8 0.0 0.54 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KKK22508.1 - 0.038 13.2 0.0 4.5 6.4 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 KKK22508.1 - 0.043 14.3 0.0 0.82 10.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 KKK22508.1 - 0.096 12.6 0.4 0.3 11.0 0.3 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KKK22508.1 - 0.15 11.6 0.3 3.3 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KKK22508.1 - 0.23 11.0 0.5 13 5.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KKK22508.1 - 0.24 11.7 0.1 0.96 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KKK22508.1 - 0.41 9.3 0.6 3 6.5 0.1 2.1 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 KKK22508.1 - 0.9 8.9 1.9 1.4 8.2 0.3 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 KKK22508.1 - 1.2 8.0 0.0 2.7 6.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KKK22508.1 - 1.4 9.2 3.5 0.6 10.4 0.4 1.9 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.18 KKK22508.1 - 1.7 8.4 2.8 1.4 8.7 0.0 2.3 3 0 0 3 3 2 0 Dynamin family DUF1752 PF08550.5 KKK22509.1 - 3.9e-10 39.1 3.0 7.1e-10 38.2 2.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUI1 PF01253.17 KKK22510.1 - 1.1e-20 73.2 2.1 2.1e-20 72.3 1.5 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Glyco_transf_8 PF01501.15 KKK22511.1 - 1.9e-05 24.1 0.4 0.00012 21.4 0.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KKK22511.1 - 0.0055 16.1 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DHquinase_I PF01487.10 KKK22512.1 - 3e-45 154.6 0.0 4.2e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KKK22512.1 - 5.7e-19 68.5 0.2 1.5e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.15 KKK22512.1 - 3.2e-13 49.9 0.1 1.6e-12 47.6 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 KKK22512.1 - 1.5e-12 47.3 0.0 5e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain F420_oxidored PF03807.12 KKK22512.1 - 0.024 15.0 0.1 0.066 13.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Vps23_core PF09454.5 KKK22512.1 - 0.031 13.8 0.1 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 Vps23 core domain ThiF PF00899.16 KKK22512.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 ThiF family Cytochrom_B561 PF03188.11 KKK22513.1 - 1.9e-05 24.4 7.2 1.9e-05 24.4 5.0 2.2 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KKK22513.1 - 0.00016 21.2 1.3 0.00016 21.2 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.12 KKK22513.1 - 0.00026 20.9 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 DOMON domain DUF2306 PF10067.4 KKK22513.1 - 0.025 14.6 4.9 0.063 13.3 0.3 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) Ferric_reduct PF01794.14 KKK22513.1 - 0.1 12.6 3.5 0.079 13.0 0.6 2.1 2 0 0 2 2 2 0 Ferric reductase like transmembrane component CopD PF05425.8 KKK22513.1 - 2.1 8.5 9.2 0.32 11.2 0.7 2.8 1 1 1 2 2 2 0 Copper resistance protein D Chromate_transp PF02417.10 KKK22514.1 - 3.1e-53 179.8 25.3 1e-28 100.0 8.7 2.3 2 0 0 2 2 2 2 Chromate transporter Spt5-NGN PF03439.8 KKK22514.1 - 0.04 13.6 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section F-box-like PF12937.2 KKK22515.1 - 1e-05 25.1 3.5 2e-05 24.2 0.2 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KKK22515.1 - 0.0068 16.0 0.5 0.022 14.4 0.4 1.9 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.13 KKK22516.1 - 5.8e-19 67.9 0.0 1.4e-18 66.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22516.1 - 7.5e-08 32.1 13.8 1.4e-07 31.3 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fringe PF02434.11 KKK22517.1 - 2e-09 37.0 0.2 2e-06 27.2 0.0 3.8 3 1 0 3 3 3 1 Fringe-like PAN_1 PF00024.21 KKK22517.1 - 0.0044 16.7 0.3 0.0085 15.8 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 KKK22517.1 - 0.032 13.9 1.1 0.081 12.6 0.7 1.6 1 0 0 1 1 1 0 PAN domain Mito_carr PF00153.22 KKK22518.1 - 9e-68 224.0 0.1 1.7e-23 82.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.9 KKK22519.1 - 2.1e-40 137.2 27.6 2.4e-40 137.0 19.1 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 KKK22519.1 - 0.11 12.8 10.1 0.12 12.7 7.0 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal SprA-related PF12118.3 KKK22519.1 - 0.24 10.6 10.3 0.27 10.5 7.1 1.1 1 0 0 1 1 1 0 SprA-related family Vfa1 PF08432.5 KKK22519.1 - 0.87 9.5 13.9 1 9.3 9.6 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Asp-B-Hydro_N PF05279.6 KKK22519.1 - 1.4 8.7 10.8 1.5 8.5 7.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DRY_EERY PF09750.4 KKK22519.1 - 2 8.5 8.4 2.5 8.2 5.8 1.3 1 0 0 1 1 1 0 Alternative splicing regulator THOC7 PF05615.8 KKK22519.1 - 3.7 7.8 18.0 5.1 7.3 12.5 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Hom_end_hint PF05203.11 KKK22519.1 - 4.1 7.0 6.9 4.6 6.9 4.8 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint GAGA_bind PF06217.7 KKK22519.1 - 9.4 6.0 11.8 10 5.9 8.1 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family TMPIT PF07851.8 KKK22519.1 - 9.7 5.1 7.8 11 4.9 5.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.1 KKK22520.1 - 0.00027 19.5 0.6 0.00035 19.2 0.4 1.1 1 0 0 1 1 1 1 AAA domain BicD PF09730.4 KKK22520.1 - 0.0031 15.9 0.5 0.0044 15.4 0.3 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Spc7 PF08317.6 KKK22520.1 - 0.0066 15.1 0.8 0.009 14.7 0.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein GAS PF13851.1 KKK22520.1 - 0.012 14.7 4.2 0.021 14.0 2.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phlebovirus_NSM PF07246.6 KKK22520.1 - 0.051 12.7 0.7 0.087 11.9 0.5 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1664 PF07889.7 KKK22520.1 - 0.087 12.6 0.6 0.56 10.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GLTP PF08718.6 KKK22520.1 - 0.1 12.6 0.1 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) HAUS6_N PF14661.1 KKK22520.1 - 0.11 11.8 1.5 0.16 11.3 1.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Syntaxin PF00804.20 KKK22520.1 - 0.11 12.7 5.0 0.054 13.6 0.8 2.3 1 1 1 2 2 2 0 Syntaxin IncA PF04156.9 KKK22520.1 - 0.14 11.7 8.6 0.036 13.6 3.3 1.9 2 0 0 2 2 2 0 IncA protein DUF4140 PF13600.1 KKK22520.1 - 0.14 12.5 2.6 0.32 11.4 1.8 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF607 PF04678.8 KKK22520.1 - 0.22 11.4 1.2 0.49 10.3 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF607 TBPIP PF07106.8 KKK22520.1 - 0.83 9.1 3.6 1.2 8.6 2.2 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Matrilin_ccoil PF10393.4 KKK22520.1 - 1.3 8.4 3.5 8.8 5.7 0.0 2.8 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Brix PF04427.13 KKK22523.1 - 2.6e-45 154.4 0.0 3.3e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.5 KKK22524.1 - 1.8e-73 245.1 3.1 1.9e-73 245.0 1.2 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KKK22524.1 - 8.2e-60 201.6 0.0 1.3e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK22524.1 - 2.3e-57 194.3 0.8 3.5e-57 193.7 0.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK22524.1 - 1.2e-14 53.8 0.2 3.3e-14 52.3 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KKK22524.1 - 6.1e-12 45.5 0.1 1.3e-10 41.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KKK22524.1 - 8.7e-08 32.1 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KKK22524.1 - 5.8e-05 22.7 0.2 0.59 9.6 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KKK22524.1 - 0.00058 19.5 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 KKK22524.1 - 0.0014 17.6 0.9 0.0095 14.9 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 KKK22524.1 - 0.0021 17.0 0.1 0.36 9.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.16 KKK22524.1 - 0.0067 15.7 0.1 0.047 12.9 0.0 2.2 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KKK22524.1 - 0.01 15.3 0.0 0.027 13.9 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.1 KKK22524.1 - 0.016 15.1 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 KKK22524.1 - 0.029 13.4 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KKK22524.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KKK22524.1 - 0.096 12.8 0.1 0.34 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain zf-RanBP PF00641.13 KKK22524.1 - 3.3 6.9 7.4 0.36 9.9 1.6 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Homeobox PF00046.24 KKK22526.1 - 1.3e-16 59.9 3.9 2.3e-16 59.1 2.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KKK22526.1 - 0.024 14.3 0.2 0.086 12.5 0.1 2.0 1 0 0 1 1 1 0 Homeobox KN domain ADH_zinc_N PF00107.21 KKK22528.1 - 2.4e-05 23.9 0.1 5.7e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK22528.1 - 0.0023 18.8 0.1 0.0026 18.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Lipase_GDSL_2 PF13472.1 KKK22529.1 - 1.9e-13 50.9 0.1 1.5e-11 44.7 0.0 2.3 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KKK22529.1 - 5.8e-07 29.5 0.0 4.3e-06 26.7 0.0 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ECH PF00378.15 KKK22529.1 - 0.11 11.6 0.0 0.45 9.5 0.0 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family Glyco_hydro_18 PF00704.23 KKK22530.1 - 1.1e-29 103.9 0.0 1.4e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Acetyltransf_13 PF13880.1 KKK22531.1 - 1.3e-30 104.9 0.0 3.1e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KKK22531.1 - 1.2e-17 63.1 0.4 2.3e-17 62.2 0.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO EMG1 PF03587.9 KKK22533.1 - 1.8e-78 262.5 0.0 2e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF2813 PF11398.3 KKK22533.1 - 0.12 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) GFA PF04828.9 KKK22534.1 - 0.0004 20.2 0.9 0.00058 19.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme V-SNARE PF05008.10 KKK22535.1 - 0.21 11.7 2.4 0.5 10.5 1.7 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus CybS PF05328.7 KKK22536.1 - 6.4e-53 177.9 0.0 8.1e-53 177.5 0.0 1.1 1 0 0 1 1 1 1 CybS Maf PF02545.9 KKK22537.1 - 2.1e-43 147.7 0.0 3.2e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.21 KKK22537.1 - 1e-06 28.3 0.0 1e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nucleoplasmin PF03066.10 KKK22537.1 - 0.021 14.3 2.9 0.035 13.6 2.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin ADH_zinc_N PF00107.21 KKK22538.1 - 7.4e-22 77.2 0.0 1.1e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK22538.1 - 2.2e-06 28.5 0.0 4.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KKK22539.1 - 1.5e-15 56.7 0.6 6.1e-15 54.7 0.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1338 PF07063.8 KKK22540.1 - 4.1e-94 315.0 0.2 5.2e-94 314.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Slx4 PF09494.5 KKK22540.1 - 0.064 13.0 0.0 0.45 10.3 0.0 2.5 2 0 0 2 2 2 0 Slx4 endonuclease RIB43A PF05914.7 KKK22541.1 - 0.00078 18.1 0.3 0.0011 17.6 0.2 1.1 1 0 0 1 1 1 1 RIB43A Ribosomal_L21p PF00829.16 KKK22541.1 - 0.047 13.8 0.0 0.17 12.0 0.0 1.9 1 1 1 2 2 2 0 Ribosomal prokaryotic L21 protein DUF605 PF04652.11 KKK22541.1 - 0.12 11.7 9.3 0.16 11.3 6.5 1.1 1 0 0 1 1 1 0 Vta1 like Mucin PF01456.12 KKK22541.1 - 1.3 8.7 9.6 2.1 8.0 6.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein ORC6 PF05460.8 KKK22541.1 - 1.8 7.5 9.7 2.7 7.0 6.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF822 PF05687.8 KKK22541.1 - 6.3 7.1 9.1 3.5 7.9 0.2 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) Ribosomal_S8e PF01201.17 KKK22542.1 - 1.3e-35 122.4 5.1 4.5e-35 120.6 3.5 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 KKK22542.1 - 1.8 8.7 7.9 3.6 7.7 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Pkinase PF00069.20 KKK22544.1 - 5.3e-47 160.1 0.0 8e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22544.1 - 2.6e-17 62.7 0.0 3.9e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK22544.1 - 0.0004 19.4 0.0 0.00066 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KKK22544.1 - 0.0012 18.2 0.2 0.0022 17.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KKK22544.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PsaA_PsaB PF00223.14 KKK22544.1 - 0.062 11.3 0.0 0.094 10.7 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein APH PF01636.18 KKK22544.1 - 0.096 12.3 0.1 0.33 10.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1903 PF08991.5 KKK22545.1 - 0.0017 18.5 0.3 0.0032 17.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KKK22545.1 - 0.21 11.5 4.5 0.32 10.9 0.9 2.5 2 1 0 2 2 2 0 CHCH domain BAR_2 PF10455.4 KKK22546.1 - 0.17 10.7 1.4 0.3 9.9 0.9 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Ribosomal_L36e PF01158.13 KKK22547.1 - 1e-24 86.3 0.3 1.1e-24 86.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e NatB_MDM20 PF09797.4 KKK22549.1 - 6.5e-105 350.8 0.0 1e-104 350.1 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 KKK22549.1 - 0.00012 22.3 4.6 0.0048 17.2 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK22549.1 - 0.0011 19.6 2.9 0.01 16.4 0.4 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK22549.1 - 0.0093 16.5 2.7 13 6.7 0.5 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4363 PF14276.1 KKK22549.1 - 0.14 11.8 1.3 9.4 5.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) zf-RING_2 PF13639.1 KKK22550.1 - 5.6e-09 35.6 6.7 5.6e-09 35.6 4.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KKK22550.1 - 1.4e-08 34.2 4.6 1.4e-08 34.2 3.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK22550.1 - 1.5e-07 31.2 7.0 1.5e-07 31.2 4.8 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK22550.1 - 2.5e-07 30.2 2.8 2.5e-07 30.2 2.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KKK22550.1 - 4.7e-07 29.5 7.7 4.7e-07 29.5 5.3 2.3 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KKK22550.1 - 8.5e-07 28.5 5.4 8.5e-07 28.5 3.7 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KKK22550.1 - 0.00086 18.9 2.7 0.0019 17.8 1.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KKK22550.1 - 0.0042 16.8 2.7 0.0042 16.8 1.9 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DZR PF12773.2 KKK22550.1 - 0.006 16.3 9.9 0.66 9.8 0.1 2.6 2 0 0 2 2 2 2 Double zinc ribbon zf-rbx1 PF12678.2 KKK22550.1 - 0.057 13.5 8.5 0.031 14.3 2.3 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KKK22550.1 - 0.21 11.2 9.4 0.043 13.4 1.9 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KKK22550.1 - 0.46 10.3 6.0 0.07 12.9 0.7 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 KKK22550.1 - 4.1 7.3 12.0 29 4.6 4.7 3.0 1 1 1 2 2 2 0 IBR domain MFS_1 PF07690.11 KKK22551.1 - 0.00011 21.0 5.5 0.0025 16.6 1.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily BPD_transp_1 PF00528.17 KKK22551.1 - 0.013 15.0 0.7 0.59 9.6 0.3 2.1 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component Gate PF07670.9 KKK22551.1 - 0.69 9.8 3.0 0.6 10.0 0.5 1.9 2 1 0 2 2 2 0 Nucleoside recognition DUF204 PF02659.10 KKK22551.1 - 0.69 10.0 5.7 11 6.1 1.3 3.0 2 2 2 4 4 4 0 Domain of unknown function DUF Ank_2 PF12796.2 KKK22567.1 - 6.3e-74 244.3 16.8 1.4e-16 60.5 0.0 7.0 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KKK22567.1 - 2.8e-63 206.7 9.1 3e-08 33.0 0.0 12.8 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 KKK22567.1 - 5e-57 189.3 9.4 4.7e-11 42.8 0.0 12.2 5 3 8 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK22567.1 - 7.1e-48 155.8 6.0 8.3e-07 28.6 0.0 12.9 13 0 0 13 13 13 9 Ankyrin repeat Ank_5 PF13857.1 KKK22567.1 - 4.2e-43 144.3 6.4 5.2e-10 39.2 0.0 9.5 7 1 3 10 10 9 8 Ankyrin repeats (many copies) AAA_22 PF13401.1 KKK22567.1 - 2.1e-08 34.3 0.0 5.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KKK22567.1 - 4.3e-08 32.9 0.0 1.2e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KKK22567.1 - 1.5e-05 25.0 0.0 3.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KKK22567.1 - 0.00016 20.6 0.0 0.00027 19.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 KKK22567.1 - 0.00028 21.0 0.0 0.00098 19.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK22567.1 - 0.00064 19.6 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KKK22567.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 KKK22567.1 - 0.028 15.2 0.0 0.099 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Asp_protease_2 PF13650.1 KKK22567.1 - 0.045 14.2 0.0 0.39 11.2 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease AAA_25 PF13481.1 KKK22567.1 - 0.079 12.3 0.0 0.38 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KKK22567.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Fungal_trans_2 PF11951.3 KKK22569.1 - 6.1e-79 265.3 0.0 8e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22569.1 - 2.4e-07 30.5 7.0 2.4e-07 30.5 4.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 KKK22570.1 - 2.4e-10 40.0 0.1 4.6e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KKK22570.1 - 2.8e-09 36.9 0.2 7.8e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 KKK22570.1 - 2.4e-05 24.2 0.0 5.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH PF00169.24 KKK22570.1 - 0.00053 20.1 0.9 0.002 18.3 0.6 2.1 1 1 0 1 1 1 1 PH domain SAM_PNT PF02198.11 KKK22570.1 - 0.062 13.0 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain PH_10 PF15411.1 KKK22573.1 - 6e-25 87.6 0.1 1.1e-24 86.8 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KKK22573.1 - 1.4e-11 44.3 0.0 7.1e-11 42.0 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KKK22573.1 - 3.3e-08 33.2 5.1 6.5e-08 32.2 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 KKK22573.1 - 2.4e-07 30.6 0.0 4.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 KKK22573.1 - 0.00013 21.6 3.9 0.00023 20.8 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KKK22573.1 - 0.00069 19.5 4.0 0.0013 18.7 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK22573.1 - 0.0054 16.3 4.2 0.0098 15.5 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK22573.1 - 0.0058 16.7 1.2 0.011 15.7 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING-like PF08746.6 KKK22573.1 - 0.047 13.7 4.5 0.087 12.8 3.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-UDP PF14569.1 KKK22573.1 - 0.22 11.3 1.2 0.43 10.3 0.8 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Fungal_trans PF04082.13 KKK22574.1 - 2.5e-08 33.0 0.1 4.1e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KKK22575.1 - 1.1e-11 43.9 0.0 8.5e-05 21.2 0.0 3.2 1 1 1 2 2 2 2 Cytochrome P450 TPR_12 PF13424.1 KKK22576.1 - 1.4e-09 37.7 29.0 0.00014 21.7 0.1 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat AAA_22 PF13401.1 KKK22576.1 - 9.2e-07 29.0 0.2 0.0014 18.7 0.0 3.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK22576.1 - 3.6e-06 27.1 5.2 8.7e-06 25.8 0.0 4.3 4 2 1 5 5 5 1 AAA ATPase domain NACHT PF05729.7 KKK22576.1 - 1.3e-05 24.9 0.0 5.4e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 KKK22576.1 - 0.021 15.4 18.7 16 6.4 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 KKK22577.1 - 1.3e-55 188.2 0.0 1.7e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK22577.1 - 5.8e-07 28.4 0.0 7.6e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK22577.1 - 1.8e-06 27.7 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KKK22577.1 - 5.4e-05 22.0 0.6 0.0017 17.1 0.0 2.3 3 0 0 3 3 3 1 Carboxylesterase family Chlorophyllase2 PF12740.2 KKK22577.1 - 0.00045 19.1 0.0 0.00076 18.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2305 PF10230.4 KKK22577.1 - 0.00089 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 KKK22577.1 - 0.018 14.4 0.2 0.18 11.2 0.1 2.0 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 KKK22577.1 - 0.042 13.0 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_transf_28 PF03033.15 KKK22578.1 - 4.3e-17 62.1 0.1 2.7e-15 56.3 0.0 2.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.6 KKK22578.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 ATG C terminal domain Glyco_hydro_76 PF03663.9 KKK22580.1 - 4.9e-136 453.9 23.1 6.6e-136 453.5 16.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cation_efflux PF01545.16 KKK22581.1 - 3.1e-72 243.0 4.3 3.7e-72 242.7 3.0 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 KKK22581.1 - 0.00031 19.8 0.0 0.00031 19.8 0.0 1.7 2 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component Pyr_redox PF00070.22 KKK22582.1 - 3.9e-16 59.2 0.0 5.2e-12 46.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK22582.1 - 4.1e-11 43.1 0.0 1.1e-10 41.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK22582.1 - 9.5e-09 34.6 0.4 0.0017 17.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KKK22582.1 - 4e-07 29.2 0.1 9.1e-07 28.1 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KKK22582.1 - 3.2e-05 24.0 0.4 0.0013 18.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KKK22582.1 - 9.4e-05 22.3 0.0 0.048 13.6 0.0 2.8 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.1 KKK22582.1 - 0.00017 21.5 0.1 0.6 10.1 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KKK22582.1 - 0.0002 20.1 0.0 0.2 10.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_7 PF13241.1 KKK22582.1 - 0.00022 21.4 0.1 0.046 13.9 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KKK22582.1 - 0.0072 15.2 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DUF4147 PF13660.1 KKK22582.1 - 0.046 12.8 0.2 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) UDPG_MGDP_dh_N PF03721.9 KKK22582.1 - 0.05 12.9 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain APH PF01636.18 KKK22583.1 - 0.0013 18.5 0.7 0.0013 18.5 0.5 3.0 2 2 0 2 2 2 1 Phosphotransferase enzyme family Spore_coat_CotO PF14153.1 KKK22583.1 - 0.0045 16.4 13.7 0.012 15.1 5.4 2.3 2 0 0 2 2 2 2 Spore coat protein CotO HSDR_N_2 PF13588.1 KKK22583.1 - 0.018 14.8 0.1 0.36 10.6 0.0 2.4 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Pkinase_Tyr PF07714.12 KKK22583.1 - 0.051 12.6 0.0 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase OmpH PF03938.9 KKK22583.1 - 0.78 9.6 16.5 16 5.3 10.8 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) SAPS PF04499.10 KKK22583.1 - 2.6 6.6 10.5 2.2 6.7 2.7 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 KKK22583.1 - 3.1 5.3 11.8 0.3 8.7 4.3 1.8 2 0 0 2 2 2 0 Ycf1 GST_C_2 PF13410.1 KKK22584.1 - 2e-08 33.9 2.8 3.8e-08 33.1 1.4 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KKK22584.1 - 6.7e-08 32.4 0.0 1.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KKK22584.1 - 2.6e-07 30.7 0.0 5.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK22584.1 - 0.0032 17.4 0.1 0.0063 16.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK22584.1 - 0.0098 16.3 0.2 0.022 15.2 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_4 PF14834.1 KKK22584.1 - 0.069 13.0 0.2 0.14 12.0 0.1 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OmdA PF13376.1 KKK22584.1 - 1 9.0 3.7 0.27 10.9 0.2 1.9 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated FAD_binding_3 PF01494.14 KKK22586.1 - 2.7e-29 102.3 0.0 2.6e-28 99.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK22586.1 - 1.2e-05 25.2 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KKK22586.1 - 6.2e-05 21.9 0.0 0.0034 16.2 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KKK22586.1 - 9.9e-05 21.3 0.1 0.013 14.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KKK22586.1 - 0.00021 20.3 0.4 0.057 12.3 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KKK22586.1 - 0.00025 19.8 0.1 0.64 8.5 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.9 KKK22586.1 - 0.00031 19.3 0.0 0.016 13.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KKK22586.1 - 0.00038 20.3 0.1 0.00088 19.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK22586.1 - 0.0014 17.5 0.0 0.003 16.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KKK22586.1 - 0.0069 16.4 0.0 0.095 12.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK22586.1 - 0.02 14.6 0.1 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KKK22586.1 - 0.02 15.2 0.0 2.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK22586.1 - 0.038 13.0 0.0 5 6.0 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AAA PF00004.24 KKK22592.1 - 1.1e-97 323.3 0.0 1.8e-47 160.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KKK22592.1 - 1.7e-14 54.1 0.0 6.9e-08 32.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KKK22592.1 - 8.2e-14 51.2 0.0 6.1e-06 25.4 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KKK22592.1 - 3.3e-13 49.7 0.0 5.4e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KKK22592.1 - 1.5e-12 47.4 0.7 4.2e-06 26.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KKK22592.1 - 5e-12 46.0 0.2 0.0015 18.6 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK22592.1 - 2e-11 44.7 0.0 0.00036 21.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK22592.1 - 4.9e-11 42.9 0.0 0.0017 18.3 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 KKK22592.1 - 2.1e-09 36.6 0.1 0.00076 18.2 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 KKK22592.1 - 2.5e-08 33.5 4.5 0.027 13.8 0.0 4.2 2 2 1 4 4 4 2 AAA domain CDC48_2 PF02933.12 KKK22592.1 - 2.7e-08 33.3 0.0 6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 KKK22592.1 - 3.2e-08 33.5 0.0 0.0028 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KKK22592.1 - 4.4e-08 32.7 0.0 0.0044 16.4 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KKK22592.1 - 9e-08 31.5 0.9 0.007 15.5 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KKK22592.1 - 9.3e-08 31.4 0.0 0.0058 15.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 KKK22592.1 - 1e-07 31.5 1.3 0.0068 16.1 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 KKK22592.1 - 3.6e-07 30.3 0.0 0.02 15.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 KKK22592.1 - 1.1e-06 27.9 0.8 0.37 9.8 0.1 3.4 2 1 1 3 3 3 2 KaiC ResIII PF04851.10 KKK22592.1 - 1.7e-06 28.0 0.0 0.0027 17.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.1 KKK22592.1 - 3.7e-06 27.2 0.0 0.069 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KKK22592.1 - 4e-06 26.8 0.1 0.074 13.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.1 KKK22592.1 - 5e-06 26.2 0.5 0.079 12.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 KKK22592.1 - 7.5e-06 25.0 0.0 0.0089 14.9 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 KKK22592.1 - 8.9e-06 24.7 0.1 0.037 12.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KKK22592.1 - 1.3e-05 24.7 0.1 0.23 10.9 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KKK22592.1 - 1.4e-05 24.8 0.0 4.4 6.9 0.0 3.9 2 2 2 4 4 4 0 Archaeal ATPase NACHT PF05729.7 KKK22592.1 - 2.1e-05 24.2 0.0 0.068 12.8 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Vps4_C PF09336.5 KKK22592.1 - 4e-05 23.4 0.0 0.00025 20.8 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.1 KKK22592.1 - 4.5e-05 23.5 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KKK22592.1 - 7.2e-05 23.1 0.0 0.36 11.1 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.13 KKK22592.1 - 0.00012 21.7 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein PhoH PF02562.11 KKK22592.1 - 0.00013 21.3 0.4 0.43 9.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 KKK22592.1 - 0.00019 21.0 0.0 0.72 9.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KKK22592.1 - 0.00021 20.9 0.0 0.31 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 KKK22592.1 - 0.00038 20.1 0.0 0.87 9.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KKK22592.1 - 0.00086 19.0 0.3 0.53 9.9 0.0 3.7 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 KKK22592.1 - 0.00087 18.3 0.0 0.96 8.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 KKK22592.1 - 0.0016 17.3 0.1 0.51 9.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.13 KKK22592.1 - 0.003 17.1 0.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 KKK22592.1 - 0.0051 15.8 0.3 0.82 8.5 0.0 3.2 2 2 2 4 4 4 1 KAP family P-loop domain AAA_10 PF12846.2 KKK22592.1 - 0.0053 16.2 0.6 1.3 8.3 0.0 3.7 3 1 1 4 4 4 1 AAA-like domain IPT PF01745.11 KKK22592.1 - 0.0099 15.0 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase Zot PF05707.7 KKK22592.1 - 0.019 14.4 0.1 9 5.7 0.1 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) T2SE PF00437.15 KKK22592.1 - 0.036 12.9 0.0 4.4 6.1 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein SKI PF01202.17 KKK22592.1 - 0.054 13.3 0.1 6.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase AFG1_ATPase PF03969.11 KKK22592.1 - 0.056 12.2 0.0 8.1 5.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase UPF0079 PF02367.12 KKK22592.1 - 0.067 12.8 0.1 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DEAD PF00270.24 KKK22592.1 - 0.11 11.9 0.4 52 3.2 0.0 3.4 3 1 1 4 4 3 0 DEAD/DEAH box helicase KTI12 PF08433.5 KKK22592.1 - 0.13 11.4 0.1 9.2 5.3 0.0 2.5 2 1 0 2 2 2 0 Chromatin associated protein KTI12 MobB PF03205.9 KKK22592.1 - 0.13 11.9 0.0 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KKK22592.1 - 0.34 11.2 1.0 3.6 7.8 0.0 2.5 3 0 0 3 3 2 0 AAA domain EnY2 PF10163.4 KKK22593.1 - 0.064 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Transcription factor e(y)2 RRP7 PF12923.2 KKK22596.1 - 1.1e-32 112.8 11.2 1.1e-32 112.8 7.8 2.4 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 KKK22596.1 - 0.057 13.4 0.4 0.58 10.1 0.0 2.7 3 1 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK22596.1 - 0.087 12.4 0.3 5.1 6.7 0.0 3.0 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dak1_2 PF13684.1 KKK22596.1 - 0.33 9.8 4.0 1.1 8.1 0.1 2.3 1 1 0 2 2 2 0 Dihydroxyacetone kinase family Bd3614_N PF14442.1 KKK22597.1 - 0.48 10.3 7.0 2.3 8.1 4.5 2.2 2 1 0 2 2 2 0 Bd3614-like deaminase N-terminal DUF2458 PF10454.4 KKK22598.1 - 3.1e-25 88.8 2.0 4.2e-25 88.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Sec66 PF09802.4 KKK22598.1 - 0.017 14.4 0.4 0.026 13.9 0.3 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 CAF-1_p150 PF11600.3 KKK22598.1 - 0.027 13.8 3.4 0.034 13.5 2.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med3 PF11593.3 KKK22598.1 - 0.045 13.0 3.4 0.051 12.8 2.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AflR PF08493.5 KKK22598.1 - 8.2 5.3 14.4 3.6 6.5 8.3 1.6 1 1 1 2 2 2 0 Aflatoxin regulatory protein DAHP_synth_1 PF00793.15 KKK22599.1 - 3.4e-96 321.1 0.0 4.2e-96 320.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.1 KKK22600.1 - 6.3e-20 70.5 0.6 6.3e-20 70.5 0.4 1.7 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF605 PF04652.11 KKK22600.1 - 0.0025 17.2 0.9 0.0025 17.2 0.6 1.9 2 0 0 2 2 2 1 Vta1 like adh_short PF00106.20 KKK22601.1 - 2e-09 37.5 0.1 1.7e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK22601.1 - 8.9e-05 22.2 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Thiolase_N PF00108.18 KKK22602.1 - 8.6e-79 264.2 0.1 1.4e-78 263.5 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK22602.1 - 5.3e-44 148.5 1.9 1.2e-43 147.4 0.8 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain Ribosomal_L50 PF10501.4 KKK22603.1 - 2.4e-24 85.4 0.3 4.1e-24 84.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S Rtf2 PF04641.7 KKK22604.1 - 8.3e-74 248.0 3.2 1.4e-73 247.3 2.2 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KKK22604.1 - 1.1e-07 31.4 0.4 3e-07 30.0 0.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KKK22604.1 - 1.4e-07 30.9 0.6 0.0063 16.0 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 KKK22604.1 - 0.00076 19.1 0.2 0.0019 17.8 0.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK22604.1 - 0.0039 16.8 0.1 0.0085 15.7 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK22604.1 - 0.023 14.5 0.1 0.085 12.6 0.1 1.9 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 KKK22604.1 - 0.026 14.5 0.1 0.09 12.8 0.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pol_alpha_B_N PF08418.5 KKK22604.1 - 0.24 10.8 8.8 0.43 10.0 6.1 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Macoilin PF09726.4 KKK22604.1 - 2.6 6.2 9.8 3.4 5.8 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein PRKCSH-like PF12999.2 KKK22605.1 - 1.4e-44 151.7 17.3 1.5e-27 96.3 0.8 3.9 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KKK22605.1 - 2.2e-32 111.6 1.9 1.2e-31 109.2 0.2 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KKK22605.1 - 4.9e-10 40.0 0.1 1.4e-09 38.6 0.1 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Fib_alpha PF08702.5 KKK22605.1 - 0.00051 20.1 3.1 0.99 9.5 0.0 3.0 3 0 0 3 3 3 2 Fibrinogen alpha/beta chain family IncA PF04156.9 KKK22605.1 - 0.1 12.2 12.8 1.4 8.4 5.7 2.4 2 0 0 2 2 2 0 IncA protein Sec2p PF06428.6 KKK22605.1 - 0.23 11.3 14.0 0.86 9.4 0.0 3.3 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p GrpE PF01025.14 KKK22605.1 - 0.25 10.8 16.5 6 6.3 7.6 3.0 2 1 0 2 2 2 0 GrpE DUF4140 PF13600.1 KKK22605.1 - 0.49 10.8 0.1 0.49 10.8 0.1 3.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Ldl_recept_a PF00057.13 KKK22605.1 - 0.7 9.8 8.5 0.36 10.7 0.8 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Snapin_Pallidin PF14712.1 KKK22605.1 - 1.7 9.0 6.3 4.6 7.6 0.0 3.3 3 0 0 3 3 3 0 Snapin/Pallidin ATG16 PF08614.6 KKK22605.1 - 4.4 7.0 15.4 7.6 6.3 0.1 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF641 PF04859.7 KKK22605.1 - 6.1 6.5 12.5 6.9 6.4 0.1 2.8 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DNA_pol_A_exo1 PF01612.15 KKK22614.1 - 1.5e-41 141.8 0.0 2.8e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KKK22614.1 - 2.4e-27 95.0 0.7 8e-27 93.3 0.5 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KKK22614.1 - 4.8e-11 42.2 0.1 2e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 HRDC domain UPF0203 PF05254.7 KKK22615.1 - 4.2e-24 84.1 1.4 5.2e-24 83.8 1.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 KKK22615.1 - 0.00083 19.3 0.3 0.0016 18.4 0.2 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KKK22615.1 - 0.19 11.5 2.2 1.5 8.6 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Prp18 PF02840.10 KKK22647.1 - 3e-55 186.0 0.2 3e-55 186.0 0.1 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KKK22647.1 - 4.2e-09 35.4 6.3 4.2e-09 35.4 4.3 3.2 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like MIP-T3 PF10243.4 KKK22647.1 - 0.023 13.1 24.2 0.028 12.8 16.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 KKK22647.1 - 1.6 6.3 7.0 1.6 6.3 4.8 1.1 1 0 0 1 1 1 0 Ycf1 CDC27 PF09507.5 KKK22647.1 - 4.7 6.3 27.0 6.7 5.8 18.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pyr_redox_3 PF13738.1 KKK22648.1 - 5.4e-05 23.3 0.0 0.0003 20.9 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK22648.1 - 0.025 14.3 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NDUF_B4 PF07225.7 KKK22649.1 - 1.7e-05 24.6 0.0 1.9e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) MitoNEET_N PF10660.4 KKK22649.1 - 0.028 14.2 0.3 0.039 13.8 0.2 1.2 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus BCCT PF02028.12 KKK22649.1 - 0.1 10.8 0.1 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 BCCT family transporter SAP18 PF06487.7 KKK22650.1 - 2.6e-48 162.8 0.0 3.2e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) 2-Hacid_dh_C PF02826.14 KKK22651.1 - 2.9e-53 179.6 0.0 3.9e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK22651.1 - 3.4e-29 100.9 0.0 4.2e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 KKK22651.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 KKK22651.1 - 0.089 12.3 0.1 14 5.2 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GST_N PF02798.15 KKK22652.1 - 6.5e-11 42.2 0.2 2.6e-10 40.3 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KKK22652.1 - 9e-11 41.8 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK22652.1 - 1.7e-09 37.5 0.0 3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK22652.1 - 2.6e-06 27.3 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK22652.1 - 2.9e-05 24.4 0.0 4.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK22652.1 - 0.00013 21.7 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Arf PF00025.16 KKK22653.1 - 1.9e-40 137.9 0.0 2e-26 92.3 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 KKK22653.1 - 4.8e-14 51.8 0.0 3.9e-07 29.1 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KKK22653.1 - 2.6e-07 30.0 0.0 4e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK22653.1 - 6.4e-07 29.8 0.0 3.5e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 KKK22653.1 - 1.4e-06 27.7 0.0 0.0047 16.3 0.0 2.8 2 1 0 2 2 2 2 Ras family SRPRB PF09439.5 KKK22653.1 - 5.1e-06 25.8 0.0 8.2e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KKK22653.1 - 1.5e-05 24.9 0.0 7.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK22653.1 - 2.7e-05 23.6 0.0 0.00083 18.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Glycos_transf_1 PF00534.15 KKK22654.1 - 2.3e-24 85.7 0.0 3.4e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KKK22654.1 - 3.7e-15 56.2 0.0 6.2e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 PIGA PF08288.7 KKK22654.1 - 9.2e-06 25.9 1.2 6.8e-05 23.1 0.2 2.4 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.1 KKK22654.1 - 0.0001 22.0 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 KKK22654.1 - 0.0045 17.2 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Fungal_trans_2 PF11951.3 KKK22674.1 - 4.6e-76 255.8 0.1 5.4e-76 255.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22674.1 - 6.6e-08 32.3 8.3 1.3e-07 31.4 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-actin_cap_A PF01267.12 KKK22675.1 - 2.2e-84 282.7 0.0 3e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PEX11 PF05648.9 KKK22675.1 - 6.8e-30 104.0 0.0 2.6e-29 102.1 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3987 PF13148.1 KKK22675.1 - 0.1 11.1 0.0 0.19 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Fungal_trans PF04082.13 KKK22676.1 - 6.7e-08 31.7 0.2 1.1e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22676.1 - 3.2e-07 30.1 10.8 7.4e-07 28.9 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med7 PF05983.6 KKK22677.1 - 3.1e-58 196.1 0.4 3.7e-58 195.8 0.3 1.1 1 0 0 1 1 1 1 MED7 protein MerR-DNA-bind PF09278.6 KKK22677.1 - 0.072 13.4 0.9 0.19 12.1 0.6 1.8 1 0 0 1 1 1 0 MerR, DNA binding PAP2 PF01569.16 KKK22678.1 - 3.8e-23 81.5 0.8 3.8e-23 81.5 0.5 2.3 2 1 0 2 2 2 1 PAP2 superfamily DUF368 PF04018.8 KKK22678.1 - 0.025 13.7 0.7 1 8.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF368) DUF3429 PF11911.3 KKK22678.1 - 0.23 11.4 4.4 2.4 8.1 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3429) DUF3975 PF13126.1 KKK22678.1 - 0.59 10.3 2.8 0.76 9.9 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3975) Virul_fac_BrkB PF03631.10 KKK22678.1 - 1.9 7.7 10.6 15 4.8 0.1 2.1 2 0 0 2 2 2 0 Virulence factor BrkB p450 PF00067.17 KKK22679.1 - 1.5e-66 224.8 0.0 1.9e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 T5orf172 PF10544.4 KKK22681.1 - 7e-12 45.6 0.0 1.6e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 KKK22681.1 - 1.1e-10 41.7 0.0 3.8e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 2-Hacid_dh_C PF02826.14 KKK22683.1 - 4.4e-13 48.7 0.1 2.5e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK22683.1 - 1e-06 28.2 0.0 1.6e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SET PF00856.23 KKK22684.1 - 0.017 15.4 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 SET domain Tannase PF07519.6 KKK22685.1 - 1.8e-82 277.6 0.0 2.4e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KKK22685.1 - 0.00016 21.5 0.1 0.00057 19.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK22685.1 - 0.0013 18.3 0.0 0.0039 16.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK22685.1 - 0.0017 17.6 0.1 0.7 9.0 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK22685.1 - 0.0031 17.2 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ras PF00071.17 KKK22686.1 - 2.6e-31 108.1 0.2 3.3e-31 107.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK22686.1 - 2.4e-20 73.1 0.1 8.4e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KKK22686.1 - 9.8e-07 28.1 0.1 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK22686.1 - 4.3e-05 22.7 0.2 5.5e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK22686.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 KKK22686.1 - 0.23 10.1 0.0 0.23 10.1 0.0 2.2 2 1 1 3 3 3 0 G-protein alpha subunit Pex14_N PF04695.8 KKK22686.1 - 1.5 8.8 8.6 3.7 7.5 5.9 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Patched PF02460.13 KKK22687.1 - 3.6e-78 263.3 12.9 9.2e-78 262.0 8.9 1.6 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KKK22687.1 - 7.7e-51 171.5 7.2 7.7e-51 171.5 5.0 2.9 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KKK22687.1 - 1.3e-06 27.3 9.8 1.3e-06 27.3 6.8 3.4 3 1 0 3 3 3 2 MMPL family ADH_N PF08240.7 KKK22688.1 - 3.1e-28 97.7 1.2 5.6e-28 96.8 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK22688.1 - 1.1e-21 76.7 0.0 2.1e-21 75.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KKK22688.1 - 0.022 14.4 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.16 KKK22688.1 - 0.029 13.9 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KKK22688.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NADH_4Fe-4S PF10589.4 KKK22688.1 - 1.9 7.7 6.1 18 4.6 4.6 2.3 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Pkinase PF00069.20 KKK22689.1 - 6.6e-25 87.7 0.0 1.2e-24 86.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22689.1 - 3.1e-05 23.1 0.0 5.9e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase NAD_binding_10 PF13460.1 KKK22691.1 - 1.2e-16 61.2 0.1 1.5e-16 60.9 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK22691.1 - 6.1e-16 58.5 0.0 8.6e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KKK22691.1 - 9.8e-11 41.3 0.1 3.2e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 KKK22691.1 - 5.1e-10 38.5 0.0 2.1e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KKK22691.1 - 1.2e-06 27.6 0.5 0.00029 19.8 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KKK22691.1 - 5e-06 25.6 0.0 7.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 KKK22691.1 - 0.0007 18.6 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KKK22691.1 - 0.022 14.6 1.3 0.042 13.7 0.1 2.1 2 1 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 KKK22691.1 - 0.16 12.3 0.5 5.5 7.3 0.1 2.4 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain HEAT PF02985.17 KKK22692.1 - 2.9e-22 76.7 0.9 7.9e-05 22.4 0.1 9.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 KKK22692.1 - 2.8e-20 72.1 10.0 2.3e-05 24.7 0.0 9.9 9 2 3 12 12 10 5 HEAT-like repeat HEAT_2 PF13646.1 KKK22692.1 - 8.4e-20 70.8 7.9 0.00011 22.3 0.0 7.6 5 3 3 8 8 8 5 HEAT repeats Cnd1 PF12717.2 KKK22692.1 - 5.1e-12 45.9 0.9 0.0013 18.5 0.1 4.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 KKK22692.1 - 5.5e-10 39.0 0.5 2e-07 30.8 0.0 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 KKK22692.1 - 1.6e-09 38.0 0.1 0.35 11.2 0.0 5.8 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KKK22692.1 - 4.5e-07 29.4 0.0 0.033 13.5 0.0 3.8 3 1 0 3 3 3 2 CLASP N terminal MMS19_C PF12460.3 KKK22692.1 - 1.7e-06 27.0 0.8 0.00061 18.6 0.0 3.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Arm PF00514.18 KKK22692.1 - 5.6e-06 25.9 0.2 3 7.8 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KKK22692.1 - 7.3e-05 21.2 0.1 0.14 10.4 0.0 3.1 3 0 0 3 3 3 2 Adaptin N terminal region ParcG PF10274.4 KKK22692.1 - 0.00071 19.5 0.5 0.042 13.7 0.1 3.2 3 1 1 4 4 4 1 Parkin co-regulated protein UME PF08064.8 KKK22692.1 - 0.00096 19.0 0.0 0.88 9.5 0.0 4.2 4 1 1 5 5 5 1 UME (NUC010) domain DUF577 PF04510.7 KKK22692.1 - 0.0032 17.1 0.0 0.032 13.9 0.0 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF577) Cohesin_HEAT PF12765.2 KKK22692.1 - 0.026 14.4 0.0 2.2 8.3 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sec7_N PF12783.2 KKK22692.1 - 0.081 12.3 0.0 0.46 9.8 0.0 2.3 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4042 PF13251.1 KKK22692.1 - 0.097 12.1 0.1 1.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) SET PF00856.23 KKK22708.1 - 9.1e-20 71.5 0.6 3.6e-19 69.6 0.1 2.2 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.11 KKK22708.1 - 2.4e-16 59.8 3.5 2.4e-16 59.8 2.4 2.5 2 0 0 2 2 2 1 Pre-SET motif Alveol-reg_P311 PF11092.3 KKK22708.1 - 0.14 12.0 0.3 0.52 10.3 0.0 2.1 3 0 0 3 3 3 0 Neuronal protein 3.1 (p311) zf-C2H2 PF00096.21 KKK22709.1 - 2.4e-27 93.5 61.9 0.00036 20.7 0.2 11.3 10 2 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK22709.1 - 1.4e-24 84.5 57.0 0.0038 17.4 0.0 10.8 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK22709.1 - 1.7e-19 69.0 54.2 5.6e-05 23.2 0.5 11.0 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KKK22709.1 - 0.0035 17.4 18.1 18 5.6 0.0 8.4 10 0 0 10 10 10 1 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 KKK22709.1 - 0.31 10.6 4.8 0.3 10.7 1.1 2.6 2 0 0 2 2 2 0 GAGA factor RNA_pol_Rpb6 PF01192.17 KKK22710.1 - 1.4e-24 85.5 0.2 2.7e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 MFS_1 PF07690.11 KKK22711.1 - 9.4e-22 77.1 51.8 2.1e-18 66.1 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily G-gamma PF00631.17 KKK22712.1 - 1.3e-25 88.8 0.0 1.6e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF3220 PF11516.3 KKK22712.1 - 0.051 13.5 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) RSS_P20 PF11757.3 KKK22712.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like PCI PF01399.22 KKK22713.1 - 1.2e-10 41.6 2.4 7.3e-10 39.0 0.0 3.3 3 0 0 3 3 3 1 PCI domain Acetyltransf_1 PF00583.19 KKK22715.1 - 5e-11 42.4 0.1 7.1e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK22715.1 - 2.6e-05 23.9 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK22715.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK22715.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK22715.1 - 0.13 12.1 0.2 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_6 PF01341.12 KKK22716.1 - 1.2e-110 369.6 0.6 1.4e-110 369.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Aldo_ket_red PF00248.16 KKK22718.1 - 1.4e-45 155.3 0.0 1.7e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Inhibitor_I78 PF11720.3 KKK22719.1 - 7.4e-14 51.2 0.0 1.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KKK22719.1 - 0.00017 21.6 0.1 0.00025 21.1 0.1 1.4 1 1 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.4 KKK22720.1 - 4.3e-32 110.3 12.8 4.3e-32 110.3 8.9 2.3 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 KKK22720.1 - 0.021 13.7 2.8 0.028 13.4 1.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sugar_tr PF00083.19 KKK22721.1 - 5.6e-100 335.0 19.3 6.4e-100 334.8 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK22721.1 - 5e-29 101.1 27.3 1.1e-19 70.3 7.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.7 KKK22722.1 - 1.3e-36 126.0 0.1 2.3e-36 125.2 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus TatD_DNase PF01026.16 KKK22723.1 - 2.5e-47 161.2 0.0 3.4e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Sox_C_TAD PF12067.3 KKK22723.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Sox C-terminal transactivation domain Fe_hyd_lg_C PF02906.9 KKK22724.1 - 2.1e-63 214.2 0.0 3.6e-63 213.4 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Cu-oxidase_2 PF07731.9 KKK22725.1 - 1.9e-47 160.2 11.4 2.1e-42 143.8 1.9 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KKK22725.1 - 5.2e-41 139.0 6.6 3.9e-38 129.8 1.1 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK22725.1 - 5.5e-40 136.8 3.9 7.4e-34 116.9 0.2 3.6 3 0 0 3 3 3 3 Multicopper oxidase COX2 PF00116.15 KKK22725.1 - 0.0027 17.5 3.1 0.68 9.7 0.1 4.2 5 0 0 5 5 5 1 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.1 KKK22725.1 - 0.0047 16.8 0.0 6.2 6.7 0.0 3.7 4 0 0 4 4 4 1 Cupredoxin-like domain Self-incomp_S1 PF05938.6 KKK22725.1 - 0.11 12.5 0.1 7 6.8 0.1 2.3 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 FTR1 PF03239.9 KKK22726.1 - 1.6e-83 280.2 8.4 2e-83 279.8 5.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3112 PF11309.3 KKK22726.1 - 0.005 16.6 0.7 0.0099 15.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DUF3180 PF11377.3 KKK22726.1 - 6.1 6.7 8.8 1.7 8.4 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) DUF924 PF06041.6 KKK22727.1 - 1.8e-46 158.2 6.6 2.7e-45 154.4 4.6 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF3435 PF11917.3 KKK22728.1 - 5.1e-131 437.2 0.2 6.8e-108 361.0 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) zf-C2H2 PF00096.21 KKK22728.1 - 0.53 10.7 4.3 1.4 9.3 3.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1295 PF06966.7 KKK22729.1 - 6.9e-10 38.6 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 KKK22729.1 - 4.6e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DNA_RNApol_7kD PF03604.8 KKK22730.1 - 2.8e-17 61.8 6.2 3.5e-17 61.5 4.3 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2197 PF09963.4 KKK22730.1 - 9.8e-05 22.2 0.6 0.02 14.8 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.2 KKK22730.1 - 0.0019 17.9 0.3 0.0027 17.4 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 KKK22730.1 - 0.012 15.3 0.3 0.014 15.0 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family PhnA_Zn_Ribbon PF08274.7 KKK22730.1 - 0.014 15.1 0.2 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DUF2318 PF10080.4 KKK22730.1 - 0.017 14.8 0.2 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TFIIS_C PF01096.13 KKK22730.1 - 0.019 14.5 0.3 3 7.5 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) A2L_zn_ribbon PF08792.5 KKK22730.1 - 0.023 14.1 2.4 0.19 11.2 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 KKK22730.1 - 0.026 14.4 0.6 0.046 13.6 0.4 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Prok-RING_1 PF14446.1 KKK22730.1 - 0.053 13.2 0.6 0.073 12.8 0.4 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 GFA PF04828.9 KKK22730.1 - 0.075 12.9 0.9 3.3 7.7 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme OrfB_Zn_ribbon PF07282.6 KKK22730.1 - 0.27 10.9 1.9 0.39 10.3 1.3 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RRN7 PF11781.3 KKK22730.1 - 0.28 10.7 4.8 0.46 10.0 0.1 2.4 2 1 1 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF951 PF06107.6 KKK22730.1 - 0.29 10.6 2.4 1.2 8.7 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) zf-C4_Topoisom PF01396.14 KKK22730.1 - 0.71 9.4 4.0 11 5.5 0.2 2.1 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn_Tnp_IS1595 PF12760.2 KKK22730.1 - 1 9.2 4.1 1.3 8.8 0.4 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 KKK22730.1 - 1.1 9.5 5.7 3.2 8.0 0.9 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_4 PF13717.1 KKK22730.1 - 2 8.1 4.3 4.1 7.1 2.2 2.0 1 1 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.4 KKK22730.1 - 3.8 7.2 5.1 19 5.0 3.8 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 Glycos_transf_3 PF00591.16 KKK22731.1 - 2.2e-55 187.8 0.0 4.4e-54 183.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KKK22731.1 - 8.3e-07 28.5 0.5 1.8e-06 27.4 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Ribosomal_L10 PF00466.15 KKK22732.1 - 0.053 13.4 0.0 0.65 9.9 0.0 2.5 1 1 0 1 1 1 0 Ribosomal protein L10 PI-PLC-X PF00388.14 KKK22733.1 - 3.8e-12 45.8 0.0 5.8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Cut8_C PF08559.5 KKK22734.1 - 3.3e-51 172.8 0.0 4.7e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KKK22734.1 - 1.4e-13 50.4 0.8 3.2e-13 49.2 0.5 1.7 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 KKK22734.1 - 4.9e-12 45.6 5.4 8.7e-12 44.8 3.8 1.4 1 0 0 1 1 1 1 Cut8 proteasome-binding domain PHD PF00628.24 KKK22735.1 - 4e-08 32.8 9.3 4e-08 32.8 6.4 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KKK22735.1 - 0.1 11.9 9.0 0.048 12.9 3.8 2.1 2 0 0 2 2 2 0 PHD-finger DIOX_N PF14226.1 KKK22737.1 - 1.3e-25 90.1 0.0 2.2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK22737.1 - 5.5e-19 68.3 0.0 1.1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rcd1 PF04078.8 KKK22738.1 - 9.3e-128 424.5 2.3 1.2e-127 424.2 1.6 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Med15 PF09606.5 KKK22738.1 - 1.8 6.7 24.6 2.2 6.3 17.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TMEM51 PF15345.1 KKK22739.1 - 0.028 14.0 0.4 0.15 11.7 0.0 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 DUF4131 PF13567.1 KKK22739.1 - 0.096 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Prefoldin_2 PF01920.15 KKK22740.1 - 1.1e-19 70.1 3.9 1.4e-19 69.8 2.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 KKK22740.1 - 0.12 12.2 5.2 0.2 11.5 0.5 2.0 2 0 0 2 2 2 0 Tropomyosin like Rootletin PF15035.1 KKK22740.1 - 0.43 10.5 3.4 0.91 9.4 0.3 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.7 KKK22740.1 - 1.7 9.0 4.6 7.5 6.9 0.9 2.2 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.6 KKK22740.1 - 3 7.7 5.1 1.7 8.6 0.2 2.5 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 KKK22740.1 - 4.5 7.6 5.8 86 3.5 4.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 KKK22740.1 - 5.8 7.0 6.3 25 4.9 1.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ApbA PF02558.11 KKK22748.1 - 2.8e-24 85.2 0.0 4.2e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KKK22748.1 - 4.1e-19 68.7 0.0 6.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 KKK22749.1 - 1e-21 76.8 0.7 1.8e-21 76.0 0.5 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BBS2_C PF14782.1 KKK22749.1 - 0.049 12.1 0.0 0.062 11.8 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF4407 PF14362.1 KKK22749.1 - 0.12 11.2 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDK2AP PF09806.4 KKK22749.1 - 0.2 11.8 5.9 0.24 11.5 4.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Macoilin PF09726.4 KKK22749.1 - 0.29 9.3 4.2 0.32 9.2 2.9 1.3 1 0 0 1 1 1 0 Transmembrane protein His_Phos_1 PF00300.17 KKK22750.1 - 7.1e-32 110.6 0.0 8.5e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AdoMet_MTase PF07757.8 KKK22751.1 - 4.5e-34 116.9 0.1 1e-32 112.5 0.1 2.3 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase CAP_N PF01213.14 KKK22751.1 - 3.3 6.8 5.9 6.6 5.9 4.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Protoglobin PF11563.3 KKK22756.1 - 1.4e-56 190.5 0.4 1.7e-56 190.2 0.3 1.1 1 0 0 1 1 1 1 Protoglobin Sel1 PF08238.7 KKK22772.1 - 1.1e-16 60.8 22.2 2.6e-07 31.0 0.0 7.1 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.23 KKK22772.1 - 0.00012 21.4 0.1 0.00082 18.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK22772.1 - 0.00031 20.3 0.2 0.00031 20.3 0.1 2.8 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KKK22772.1 - 0.0027 17.5 1.2 0.021 14.7 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK22772.1 - 0.019 15.5 1.0 0.18 12.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK22772.1 - 0.029 15.0 1.1 0.5 11.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TBPIP PF07106.8 KKK22773.1 - 4.9e-15 55.4 1.7 6.4e-15 55.1 1.2 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 KKK22773.1 - 0.002 17.5 5.2 0.0042 16.5 0.6 2.4 2 0 0 2 2 2 1 Septum formation initiator Vps51 PF08700.6 KKK22773.1 - 0.0021 17.8 0.5 0.71 9.7 0.1 2.3 2 0 0 2 2 2 1 Vps51/Vps67 EzrA PF06160.7 KKK22773.1 - 0.0027 15.9 0.9 0.0032 15.7 0.6 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4140 PF13600.1 KKK22773.1 - 0.0052 17.2 6.1 0.016 15.6 0.8 2.4 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Laminin_I PF06008.9 KKK22773.1 - 0.01 15.2 3.8 0.013 14.8 2.6 1.2 1 0 0 1 1 1 1 Laminin Domain I Seryl_tRNA_N PF02403.17 KKK22773.1 - 0.017 15.1 3.5 0.027 14.4 2.5 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ERM PF00769.14 KKK22773.1 - 0.018 14.5 3.5 0.024 14.2 2.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TraF_2 PF13729.1 KKK22773.1 - 0.037 12.8 0.1 0.044 12.5 0.1 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Mnd1 PF03962.10 KKK22773.1 - 0.079 12.6 4.6 0.12 12.0 3.2 1.3 1 0 0 1 1 1 0 Mnd1 family PhoU PF01895.14 KKK22773.1 - 0.085 13.3 0.2 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 PhoU domain DUF2730 PF10805.3 KKK22773.1 - 0.18 11.5 1.5 0.41 10.4 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) IncA PF04156.9 KKK22773.1 - 0.24 10.9 12.1 0.34 10.4 8.4 1.3 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 KKK22773.1 - 1.2 8.9 5.5 7 6.4 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) CheY-binding PF09078.6 KKK22773.1 - 1.4 8.9 4.2 15 5.6 0.4 2.3 2 0 0 2 2 2 0 CheY binding FlxA PF14282.1 KKK22773.1 - 1.5 8.8 7.1 6.7 6.7 4.9 2.0 1 1 0 1 1 1 0 FlxA-like protein DivIVA PF05103.8 KKK22773.1 - 2.3 8.2 9.2 5.2 7.1 1.6 2.3 1 1 0 2 2 2 0 DivIVA protein Lge1 PF11488.3 KKK22773.1 - 3.6 7.8 7.7 5.9 7.1 0.8 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 APG6 PF04111.7 KKK22773.1 - 5.5 5.9 8.5 15 4.4 5.9 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Mito_fiss_reg PF05308.6 KKK22774.1 - 0.015 14.6 1.2 0.03 13.6 0.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator NeA_P2 PF12312.3 KKK22774.1 - 0.055 12.7 0.4 0.086 12.0 0.2 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein WGR PF05406.10 KKK22774.1 - 0.057 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 WGR domain CAP_N PF01213.14 KKK22774.1 - 0.063 12.5 2.4 0.079 12.2 1.0 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DAP3 PF10236.4 KKK22776.1 - 3.8e-108 361.0 0.0 4.7e-108 360.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 KKK22776.1 - 0.00094 18.1 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 KKK22776.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KKK22776.1 - 0.028 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Snf7 PF03357.16 KKK22778.1 - 1.2e-18 67.0 20.0 1.3e-18 66.9 13.2 1.5 1 1 0 1 1 1 1 Snf7 PMT_C PF11647.3 KKK22778.1 - 0.035 13.6 0.0 0.14 11.7 0.0 2.0 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 BLOC1_2 PF10046.4 KKK22778.1 - 0.067 13.3 0.6 0.067 13.3 0.4 3.6 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.7 KKK22778.1 - 0.073 12.4 28.7 0.14 11.4 16.7 2.7 1 1 0 1 1 1 0 PspA/IM30 family DUF4610 PF15384.1 KKK22778.1 - 0.096 12.2 1.9 0.22 11.0 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4610) DUF885 PF05960.6 KKK22778.1 - 0.15 11.1 13.1 0.2 10.7 1.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) DUF2203 PF09969.4 KKK22778.1 - 0.9 9.7 14.6 0.05 13.8 1.9 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Syntaxin PF00804.20 KKK22778.1 - 2.6 8.2 20.7 0.082 13.0 4.5 3.1 1 1 1 2 2 2 0 Syntaxin MutS_III PF05192.13 KKK22778.1 - 4.7 6.9 10.8 25 4.5 7.5 2.2 1 1 0 1 1 1 0 MutS domain III DUF1237 PF06824.6 KKK22779.1 - 4.3e-185 615.3 0.0 5e-185 615.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) zf-C3HC4_2 PF13923.1 KKK22780.1 - 1.1e-08 34.8 20.9 2.4e-08 33.8 9.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK22780.1 - 1.3e-07 31.3 18.8 2.8e-07 30.2 9.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KKK22780.1 - 1.6e-07 30.8 13.0 1.6e-07 30.8 9.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK22780.1 - 3e-07 30.0 16.7 8.4e-07 28.6 9.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK22780.1 - 6.2e-07 28.9 17.1 6.5e-07 28.9 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 KKK22780.1 - 1.3e-06 27.7 0.0 2.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_6 PF14835.1 KKK22780.1 - 5.8e-06 25.9 5.9 5.8e-06 25.9 4.1 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KKK22780.1 - 3.7e-05 23.4 12.9 3.7e-05 23.4 9.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KKK22780.1 - 0.00012 21.6 11.7 0.00062 19.4 5.9 2.8 2 0 0 2 2 2 1 RING-type zinc-finger Mob_synth_C PF06463.8 KKK22780.1 - 0.00031 20.4 2.2 0.00069 19.3 1.5 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.2 KKK22780.1 - 0.0018 18.3 8.7 0.0024 17.9 4.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 KKK22780.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.1 KKK22780.1 - 0.1 12.1 14.1 0.089 12.3 6.9 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 KKK22780.1 - 0.3 10.5 0.1 0.3 10.5 0.0 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Apc11 PF12861.2 KKK22780.1 - 0.55 10.1 7.0 0.11 12.3 2.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-met PF12874.2 KKK22780.1 - 1.2 9.4 0.1 1.2 9.4 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CDC27 PF09507.5 KKK22781.1 - 8.4e-120 400.8 20.7 9.5e-120 400.7 14.3 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Lung_7-TM_R PF06814.8 KKK22782.1 - 2.8e-71 239.9 15.3 3.3e-71 239.6 10.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Septin PF00735.13 KKK22784.1 - 3.3e-10 39.4 0.0 5e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Septin AAA_33 PF13671.1 KKK22784.1 - 0.0054 16.6 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 KKK22784.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KKK22784.1 - 0.016 14.6 0.0 0.063 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KKK22784.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KKK22784.1 - 0.036 14.8 0.0 0.085 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK22784.1 - 0.043 13.3 0.4 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.24 KKK22784.1 - 0.059 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK22784.1 - 0.062 13.2 0.3 0.25 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.16 KKK22784.1 - 0.065 12.3 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 KKK22784.1 - 0.07 12.0 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 KKK22784.1 - 0.096 11.7 0.0 0.24 10.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 KKK22784.1 - 0.14 12.4 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KKK22784.1 - 0.15 12.3 0.0 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 KKK22784.1 - 0.19 11.7 0.0 0.9 9.5 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 KKK22784.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Frag1 PF10277.4 KKK22786.1 - 0.49 9.8 8.2 0.32 10.4 0.2 2.3 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family Lactate_perm PF02652.9 KKK22786.1 - 1.2 7.5 9.5 0.64 8.4 0.2 2.6 3 0 0 3 3 3 0 L-lactate permease DNA_mis_repair PF01119.14 KKK22787.1 - 1.8e-19 69.3 0.0 8.2e-19 67.2 0.0 2.1 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KKK22787.1 - 5.9e-13 48.6 0.0 1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KKK22787.1 - 5.2e-12 45.4 0.0 1.7e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3804 PF12707.2 KKK22787.1 - 0.036 13.6 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3804) Fungal_trans_2 PF11951.3 KKK22788.1 - 2.5e-10 39.5 1.5 1.3e-09 37.1 1.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22788.1 - 1e-06 28.4 6.4 2.2e-06 27.4 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 KKK22792.1 - 1.7e-33 115.6 0.0 1.9e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF849 PF05853.7 KKK22792.1 - 0.076 11.8 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Amino_oxidase PF01593.19 KKK22793.1 - 3.7e-53 181.2 0.1 8e-35 120.7 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 KKK22793.1 - 1.1e-17 63.8 0.1 2.7e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 KKK22793.1 - 2.7e-13 49.7 0.2 6.4e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KKK22793.1 - 5e-09 35.5 0.7 7.9e-09 34.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK22793.1 - 4.2e-08 32.5 1.3 1.2e-07 31.0 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK22793.1 - 6.8e-07 28.6 0.3 1.2e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KKK22793.1 - 2.1e-06 27.0 0.3 6e-06 25.5 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KKK22793.1 - 4.8e-06 25.9 0.8 7.2e-06 25.3 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK22793.1 - 8.9e-06 25.7 0.1 7.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK22793.1 - 1.3e-05 25.3 0.6 2.3e-05 24.5 0.2 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK22793.1 - 1.6e-05 24.0 0.5 2.8e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KKK22793.1 - 0.00038 19.0 0.3 0.00069 18.2 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KKK22793.1 - 0.0016 17.3 0.3 0.0025 16.7 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KKK22793.1 - 0.0064 16.8 0.3 0.015 15.7 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KKK22793.1 - 0.13 11.8 0.4 0.25 10.9 0.1 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2407_C PF13373.1 KKK22798.1 - 5.4e-42 143.0 0.1 5.4e-42 143.0 0.1 1.5 2 0 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KKK22798.1 - 6.6e-32 109.5 0.1 1.6e-31 108.3 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KKK22798.1 - 4.8e-05 22.6 0.0 8.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family V-SNARE PF05008.10 KKK22799.1 - 6.8e-22 77.4 6.8 6.8e-22 77.4 4.7 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KKK22799.1 - 1.9e-18 66.2 3.7 1.9e-18 66.2 2.6 2.8 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF1848 PF08902.6 KKK22799.1 - 0.095 12.2 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) DUF1978 PF09321.5 KKK22799.1 - 0.1 12.0 8.1 0.13 11.6 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) TBCA PF02970.11 KKK22799.1 - 0.21 11.6 7.6 4.2 7.5 0.2 2.9 2 1 1 3 3 3 0 Tubulin binding cofactor A H-kinase_dim PF02895.9 KKK22799.1 - 0.36 11.1 7.8 3.2 8.1 1.6 2.5 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Mer2 PF09074.5 KKK22799.1 - 1.3 8.9 7.9 7.2 6.4 5.4 2.0 1 1 0 1 1 1 0 Mer2 zf-C4H2 PF10146.4 KKK22799.1 - 3.5 7.5 6.4 0.69 9.8 0.8 1.9 1 1 0 2 2 2 0 Zinc finger-containing protein Spc7 PF08317.6 KKK22799.1 - 4 6.0 11.1 1.8 7.1 4.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 KKK22799.1 - 4.9 4.8 6.9 8.2 4.1 4.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NAD_binding_8 PF13450.1 KKK22800.1 - 2.5e-11 43.4 0.0 5.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KKK22800.1 - 7.3e-08 31.9 0.0 5.8e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KKK22800.1 - 0.00011 21.9 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KKK22800.1 - 0.00027 19.9 1.0 0.00063 18.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK22800.1 - 0.0039 17.5 0.2 0.048 14.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK22800.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK22800.1 - 0.094 11.1 0.0 6.9 5.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 KKK22800.1 - 0.21 11.4 0.0 0.45 10.3 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TIP49 PF06068.8 KKK22801.1 - 2.8e-166 553.1 2.7 5.8e-130 433.5 0.1 2.0 1 1 1 2 2 2 2 TIP49 C-terminus RuvB_N PF05496.7 KKK22801.1 - 6.8e-12 44.9 0.4 4.5e-07 29.1 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KKK22801.1 - 4.3e-09 36.6 0.2 4.5e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK22801.1 - 2.3e-06 27.7 0.0 0.00011 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK22801.1 - 6.8e-05 23.0 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KKK22801.1 - 7.7e-05 22.3 0.4 0.0002 21.0 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KKK22801.1 - 0.00056 19.6 0.2 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KKK22801.1 - 0.0013 18.1 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 KKK22801.1 - 0.0014 17.7 0.3 0.0033 16.5 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KKK22801.1 - 0.0022 17.4 0.1 0.0045 16.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KKK22801.1 - 0.015 14.4 0.3 0.69 9.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KKK22801.1 - 0.021 14.2 0.1 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 KKK22801.1 - 0.037 13.9 0.1 0.084 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KKK22801.1 - 0.062 12.4 1.3 0.13 11.3 0.1 2.1 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 KKK22801.1 - 0.062 13.6 0.2 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KKK22801.1 - 0.065 12.1 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KKK22801.1 - 0.081 13.7 0.2 0.22 12.3 0.1 1.9 2 1 0 2 2 1 0 AAA domain Ribosomal_L28 PF00830.14 KKK22802.1 - 5.1e-20 71.0 1.1 1.1e-19 70.0 0.8 1.5 1 0 0 1 1 1 1 Ribosomal L28 family Glyco_transf_34 PF05637.7 KKK22803.1 - 2.3e-62 210.6 0.0 2.9e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Steroid_dh PF02544.11 KKK22804.1 - 2.6e-31 108.3 0.2 3.6e-31 107.9 0.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KKK22804.1 - 6.6e-05 22.3 0.3 9.8e-05 21.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KKK22804.1 - 0.0012 18.9 0.2 0.0028 17.7 0.2 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase An_peroxidase PF03098.10 KKK22805.1 - 3.2e-99 332.7 0.0 6.2e-97 325.1 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KKK22805.1 - 1.1e-09 37.3 0.0 9.7e-09 34.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 DUF1741 PF08427.5 KKK22806.1 - 7.7e-93 310.3 2.1 3.9e-92 307.9 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) UPF0118 PF01594.11 KKK22806.1 - 0.048 12.6 1.3 0.1 11.6 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF20 Fe-S_biosyn PF01521.15 KKK22807.1 - 2.6e-19 69.2 0.0 3.6e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MRG PF05712.8 KKK22808.1 - 1.5e-56 190.3 0.1 2.3e-56 189.7 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KKK22808.1 - 7.6e-10 38.3 4.4 1.1e-09 37.7 2.3 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 KKK22808.1 - 0.00079 19.0 1.4 0.003 17.2 1.0 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.12 KKK22808.1 - 0.011 15.9 0.1 0.031 14.4 0.1 1.7 1 0 0 1 1 1 0 PWWP domain Cnl2_NKP2 PF09447.5 KKK22809.1 - 1.4e-27 95.1 1.3 1.4e-27 95.1 0.9 1.6 2 0 0 2 2 2 1 Cnl2/NKP2 family protein CPDase PF07823.6 KKK22809.1 - 0.076 12.4 0.1 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 Cyclic phosphodiesterase-like protein Ctf8 PF09696.5 KKK22810.1 - 1.4e-23 83.0 0.0 1.5e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Ctf8 SecY PF00344.15 KKK22811.1 - 8.2e-62 209.1 6.2 1.1e-61 208.6 4.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KKK22811.1 - 2.6e-18 65.2 0.3 8.4e-18 63.5 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p SecY PF00344.15 KKK22812.1 - 1.5e-25 89.9 0.0 1.6e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 SecY translocase RseC_MucC PF04246.7 KKK22812.1 - 0.069 12.7 0.1 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC FUN14 PF04930.10 KKK22813.1 - 1.3e-12 47.8 2.1 8.9e-12 45.1 1.4 2.0 1 1 0 1 1 1 1 FUN14 family DUF543 PF04418.7 KKK22813.1 - 0.0052 16.7 0.8 0.04 13.8 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF543) DUF4017 PF13209.1 KKK22813.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) ORC2 PF04084.9 KKK22814.1 - 1.4e-102 342.9 0.0 1.7e-102 342.6 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 FA_desaturase PF00487.19 KKK22815.1 - 0.00061 19.3 1.7 0.0015 18.0 1.2 1.6 1 1 0 1 1 1 1 Fatty acid desaturase KAR9 PF08580.5 KKK22815.1 - 0.21 9.7 6.9 0.25 9.5 4.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RP-C_C PF11800.3 KKK22815.1 - 0.97 9.1 6.6 1.3 8.7 4.6 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region DUF605 PF04652.11 KKK22815.1 - 1.4 8.1 15.3 1.5 8.1 10.6 1.0 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 KKK22815.1 - 1.6 8.3 7.0 1.8 8.2 4.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pap_E4 PF02711.9 KKK22815.1 - 4 8.3 15.1 0.48 11.2 6.8 1.9 1 1 1 2 2 2 0 E4 protein SOR_SNZ PF01680.12 KKK22816.1 - 9.5e-110 365.0 3.2 1.5e-109 364.4 2.2 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KKK22816.1 - 6.1e-09 35.3 6.1 2.7e-06 26.6 0.1 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KKK22816.1 - 0.0014 17.9 0.3 0.024 13.8 0.0 2.6 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 KKK22816.1 - 0.002 16.9 1.0 0.92 8.2 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.16 KKK22816.1 - 0.0033 16.5 0.2 0.069 12.1 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 KKK22816.1 - 0.02 13.8 0.9 0.24 10.3 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 KKK22816.1 - 0.029 13.5 0.2 0.029 13.5 0.1 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase TMP-TENI PF02581.12 KKK22816.1 - 0.087 11.9 1.0 1.5 7.9 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI Aminotran_4 PF01063.14 KKK22817.1 - 1.5e-29 103.1 0.0 2.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV zf-LITAF-like PF10601.4 KKK22827.1 - 4.4e-23 80.9 6.9 5.5e-23 80.6 4.8 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 KKK22827.1 - 0.005 16.7 0.4 0.064 13.2 0.1 2.2 2 0 0 2 2 2 1 Zinc ribbon domain Lar_restr_allev PF14354.1 KKK22827.1 - 0.17 12.1 7.4 1.2 9.5 5.1 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 KKK22827.1 - 1.1 9.1 5.1 19 5.1 3.7 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.6 KKK22827.1 - 1.7 8.5 6.1 4.8 7.0 0.1 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Dispanin PF04505.7 KKK22827.1 - 4.2 6.9 6.6 1.5 8.4 1.6 2.1 1 1 1 2 2 2 0 Interferon-induced transmembrane protein NAD_binding_2 PF03446.10 KKK22828.1 - 6.1e-40 136.7 0.1 1.1e-39 135.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KKK22828.1 - 6.8e-40 135.9 0.7 2.5e-27 95.3 0.0 2.5 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 KKK22828.1 - 0.00062 19.4 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK22828.1 - 0.0014 18.9 0.1 0.0068 16.8 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent F_bP_aldolase PF01116.15 KKK22829.1 - 7.7e-84 281.1 0.0 8.7e-84 281.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 KKK22829.1 - 0.0062 15.5 0.3 0.0096 14.9 0.2 1.2 1 0 0 1 1 1 1 Phosphotriesterase family PALP PF00291.20 KKK22829.1 - 0.013 14.7 0.7 0.021 14.0 0.5 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_24 PF13578.1 KKK22829.1 - 0.047 14.5 0.0 0.093 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fer2_3 PF13085.1 KKK22830.1 - 1.3e-31 108.6 0.0 2.2e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KKK22830.1 - 1.7e-09 37.8 6.1 1.7e-09 37.8 4.2 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KKK22830.1 - 7.7e-09 35.4 4.5 7.7e-09 35.4 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KKK22830.1 - 0.00041 20.5 4.1 0.032 14.5 0.4 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KKK22830.1 - 0.00044 20.6 2.0 0.00044 20.6 1.4 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KKK22830.1 - 0.00046 19.9 4.3 0.00046 19.9 3.0 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KKK22830.1 - 0.0062 16.2 0.2 0.0062 16.2 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KKK22830.1 - 0.018 15.4 6.1 0.018 15.4 4.2 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 KKK22830.1 - 0.78 10.3 5.0 0.85 10.2 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Nitroreductase PF00881.19 KKK22831.1 - 3e-14 53.1 0.0 3.5e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Strep_67kDa_ant PF06100.6 KKK22832.1 - 1.4e-97 327.1 0.0 3.1e-96 322.7 0.0 2.0 1 1 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 KKK22832.1 - 7.2e-05 22.7 0.1 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK22832.1 - 0.047 12.5 0.0 0.84 8.4 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK22832.1 - 0.079 12.7 0.1 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding eIF-1a PF01176.14 KKK22832.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Pec_lyase_C PF00544.14 KKK22833.1 - 7.3e-20 71.2 5.9 1.6e-19 70.2 4.1 1.6 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KKK22833.1 - 0.00034 20.4 13.8 0.021 14.5 8.6 2.3 1 1 1 2 2 2 2 Right handed beta helix region PMP1_2 PF08114.6 KKK22834.1 - 0.0067 15.8 0.3 0.0067 15.8 0.2 1.6 2 0 0 2 2 2 1 ATPase proteolipid family Zn_clus PF00172.13 KKK22835.1 - 2.4e-10 40.1 11.3 5.2e-10 39.0 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK22835.1 - 0.00019 20.1 0.0 0.00031 19.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1422 PF07226.6 KKK22835.1 - 0.16 11.7 0.2 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) RTA1 PF04479.8 KKK22836.1 - 1.5e-35 122.7 4.2 1.9e-35 122.4 2.9 1.1 1 0 0 1 1 1 1 RTA1 like protein GPI-anchored PF10342.4 KKK22837.1 - 8.8e-23 80.6 0.3 8.8e-23 80.6 0.2 3.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIA PF03153.8 KKK22837.1 - 0.41 10.4 16.1 0.49 10.2 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.17 KKK22838.1 - 1.4e-132 442.2 1.4 1.7e-132 442.0 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CN_hydrolase PF00795.17 KKK22839.1 - 2.2e-32 111.9 0.0 3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L31e PF01198.14 KKK22841.1 - 4.3e-39 132.0 1.5 5.7e-39 131.6 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e TPR_10 PF13374.1 KKK22842.1 - 8.3e-15 54.1 0.0 1.8e-05 24.4 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KKK22842.1 - 5.8e-14 51.7 0.0 8e-11 41.7 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KKK22842.1 - 5.8e-13 48.3 0.5 4.8e-12 45.3 0.4 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 KKK22842.1 - 4.3e-12 45.4 0.0 7.6e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KKK22842.1 - 6.5e-08 32.7 0.2 1.4e-06 28.3 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KKK22842.1 - 1.7e-07 31.0 0.0 3.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_11 PF13414.1 KKK22842.1 - 2.3e-06 27.1 0.0 6.6e-05 22.4 0.0 2.7 2 0 0 2 2 2 1 TPR repeat AAA_22 PF13401.1 KKK22842.1 - 4.2e-05 23.7 0.0 0.00014 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK22842.1 - 0.00011 22.0 0.0 0.0003 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_7 PF13176.1 KKK22842.1 - 0.00011 21.6 0.3 0.77 9.7 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK22842.1 - 0.0073 16.6 0.1 0.9 10.1 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK22842.1 - 0.0078 15.7 0.0 1.4 8.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK22842.1 - 0.012 15.4 0.1 7.2 6.7 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 KKK22842.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Apc3 PF12895.2 KKK22842.1 - 0.015 15.4 0.1 3.1 7.9 0.0 2.8 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA PF00004.24 KKK22842.1 - 0.038 14.1 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 KKK22842.1 - 0.045 13.1 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KKK22842.1 - 0.062 13.0 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain TPR_3 PF07720.7 KKK22842.1 - 0.089 12.6 0.1 1.6 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HSP70 PF00012.15 KKK22843.1 - 8.9e-273 905.7 8.2 1e-272 905.5 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KKK22843.1 - 1.2e-18 66.8 0.0 1.4e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KKK22843.1 - 0.00059 19.5 0.0 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KKK22843.1 - 0.00075 19.3 1.4 0.58 10.0 0.0 3.4 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 KKK22843.1 - 0.0076 15.3 0.8 0.042 12.9 0.0 2.4 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 KKK22843.1 - 0.027 13.7 0.0 0.53 9.5 0.0 2.4 1 1 1 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_C13 PF01650.13 KKK22844.1 - 7.9e-06 25.3 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family APH PF01636.18 KKK22845.1 - 6.3e-09 35.9 0.3 7.5e-06 25.8 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK22845.1 - 0.031 13.8 0.1 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase CHZ PF09649.5 KKK22846.1 - 3e-18 64.7 1.2 3e-18 64.7 0.9 2.6 3 0 0 3 3 3 1 Histone chaperone domain CHZ BUD22 PF09073.5 KKK22846.1 - 2.3 7.1 19.5 2.7 6.9 13.5 1.0 1 0 0 1 1 1 0 BUD22 Mak16 PF04874.9 KKK22846.1 - 9.9 6.3 17.3 2.4 8.2 4.0 2.2 2 0 0 2 2 2 0 Mak16 protein C-terminal region SNARE PF05739.14 KKK22847.1 - 3.7e-06 26.5 1.9 5.3e-06 26.0 1.3 1.3 1 0 0 1 1 1 1 SNARE domain WD40 PF00400.27 KKK22848.1 - 1.1e-19 69.4 0.9 4.7e-08 32.6 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF3639 PF12341.3 KKK22848.1 - 6.2e-09 35.6 0.2 6.2e-09 35.6 0.2 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KKK22848.1 - 7.1e-07 28.3 0.0 1.4e-05 24.1 0.0 2.3 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 KKK22848.1 - 1.5e-05 24.8 0.1 0.0016 18.1 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.3 KKK22848.1 - 0.0066 16.2 1.7 0.018 14.8 1.1 1.7 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DUF3312 PF11768.3 KKK22848.1 - 0.0078 14.4 0.0 0.73 7.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) IKI3 PF04762.7 KKK22848.1 - 0.023 12.5 0.4 0.075 10.8 0.0 2.0 2 1 0 2 2 2 0 IKI3 family PQQ_2 PF13360.1 KKK22848.1 - 0.023 14.1 0.1 0.14 11.5 0.1 2.4 3 1 0 3 3 3 0 PQQ-like domain Lactonase PF10282.4 KKK22848.1 - 0.032 13.3 0.0 0.5 9.4 0.0 2.2 1 1 2 3 3 3 0 Lactonase, 7-bladed beta-propeller TFIIIC_delta PF12657.2 KKK22848.1 - 0.086 12.5 0.0 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Apc4_WD40 PF12894.2 KKK22848.1 - 0.086 12.3 0.0 0.55 9.7 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.4 KKK22848.1 - 0.14 10.2 0.0 0.73 7.9 0.0 2.2 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4613 PF15390.1 KKK22848.1 - 0.26 9.3 0.0 1.4 6.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) MFS_1 PF07690.11 KKK22849.1 - 9.3e-38 129.8 28.2 3.2e-37 128.0 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK22849.1 - 3.9e-08 32.3 6.5 3.9e-08 32.3 4.5 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter DUF791 PF05631.9 KKK22849.1 - 0.011 14.4 0.9 0.011 14.4 0.6 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF791) DUF1129 PF06570.6 KKK22849.1 - 0.022 14.0 0.6 3.2 6.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF515 PF04415.7 KKK22849.1 - 0.53 8.4 6.4 0.76 7.9 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Acetyltransf_1 PF00583.19 KKK22851.1 - 4.6e-14 52.2 0.0 7.3e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK22851.1 - 7e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KKK22851.1 - 1.1e-06 28.6 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK22851.1 - 0.00014 22.0 0.0 0.00017 21.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KKK22851.1 - 0.00063 19.8 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KKK22851.1 - 0.091 12.6 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KKK22851.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GRIP PF01465.15 KKK22852.1 - 1.9e-18 65.6 0.1 4.2e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 GRIP domain Reo_sigmaC PF04582.7 KKK22852.1 - 6.4e-08 32.1 40.5 0.03 13.5 2.4 6.6 3 2 3 6 6 6 5 Reovirus sigma C capsid protein DUF869 PF05911.6 KKK22852.1 - 1e-05 24.0 121.3 0.01 14.1 10.5 4.4 1 1 3 4 4 4 4 Plant protein of unknown function (DUF869) GAS PF13851.1 KKK22852.1 - 0.00013 21.2 147.3 0.042 13.0 7.1 10.2 2 2 8 10 10 10 7 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KKK22852.1 - 0.00024 20.9 33.1 0.00043 20.1 12.7 9.8 2 2 7 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 KKK22852.1 - 0.00059 18.4 21.3 0.00059 18.4 14.7 5.5 2 2 2 5 5 5 3 AAA domain Myosin_tail_1 PF01576.14 KKK22852.1 - 0.0019 16.0 163.8 0.036 11.7 37.0 4.3 2 2 1 3 3 3 3 Myosin tail CCDC155 PF14662.1 KKK22852.1 - 0.0033 17.0 19.0 0.0033 17.0 13.2 7.0 2 2 4 6 6 3 1 Coiled-coil region of CCDC155 FliJ PF02050.11 KKK22852.1 - 0.0047 16.9 17.6 0.0047 16.9 12.2 9.4 3 3 5 9 9 8 2 Flagellar FliJ protein IncA PF04156.9 KKK22852.1 - 0.017 14.7 164.1 0.2 11.2 13.6 9.5 3 2 7 10 10 10 0 IncA protein Spc7 PF08317.6 KKK22852.1 - 0.029 13.0 133.8 0.067 11.8 13.8 7.3 2 2 4 7 7 7 0 Spc7 kinetochore protein Filament PF00038.16 KKK22852.1 - 0.3 10.5 133.9 0.0083 15.6 32.9 7.1 1 1 4 5 5 5 0 Intermediate filament protein Fib_alpha PF08702.5 KKK22852.1 - 0.48 10.5 86.9 0.13 12.3 2.8 7.9 4 2 2 7 7 7 0 Fibrinogen alpha/beta chain family WEMBL PF05701.6 KKK22852.1 - 5.2 5.4 150.1 1.1 7.6 27.6 4.7 2 2 2 4 4 4 0 Weak chloroplast movement under blue light Zn_clus PF00172.13 KKK22861.1 - 1.7e-05 24.6 13.3 1.7e-05 24.6 9.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BUD22 PF09073.5 KKK22861.1 - 0.91 8.5 7.5 1.3 8.0 5.2 1.1 1 0 0 1 1 1 0 BUD22 Nse4-Nse3_bdg PF15412.1 KKK22862.1 - 0.003 17.3 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Borrelia_REV PF03978.8 KKK22862.1 - 0.042 13.5 0.9 0.046 13.4 0.6 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein CTV_P6 PF06706.6 KKK22864.1 - 2.4 7.7 8.8 1.6 8.2 3.6 2.5 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Glyco_hydro_31 PF01055.21 KKK22865.1 - 1.4e-84 284.5 0.5 3e-84 283.3 0.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KKK22865.1 - 4e-15 55.4 0.0 1.1e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.11 KKK22866.1 - 1.3e-19 70.1 26.9 1.9e-19 69.5 18.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KKK22866.1 - 4.9e-10 38.7 0.0 1.5e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22866.1 - 2.9e-05 23.8 6.2 6e-05 22.8 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.16 KKK22867.1 - 8.9e-44 148.9 0.0 1.2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KKK22867.1 - 5.7e-11 42.2 0.0 9.5e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KKK22867.1 - 0.12 12.4 0.0 0.44 10.6 0.0 1.9 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain Yip1 PF04893.12 KKK22868.1 - 0.014 14.8 2.9 9.3 5.7 0.0 3.0 3 0 0 3 3 3 0 Yip1 domain TrbC PF04956.8 KKK22868.1 - 0.09 12.7 0.7 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family PA14_2 PF10528.4 KKK22869.1 - 1.2e-17 63.8 0.1 3.8e-17 62.2 0.1 1.9 1 0 0 1 1 1 1 GLEYA domain Glyco_hydro_11 PF00457.12 KKK22870.1 - 6.1e-73 244.0 23.4 7.2e-73 243.8 16.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Sugar_tr PF00083.19 KKK22872.1 - 2.4e-123 412.0 19.3 2.8e-123 411.8 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK22872.1 - 1.9e-21 76.1 24.1 1.9e-21 76.1 16.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TPR_14 PF13428.1 KKK22872.1 - 0.092 13.4 0.1 0.22 12.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat APH PF01636.18 KKK22873.1 - 2e-09 37.5 0.0 7.5e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK22873.1 - 0.00065 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KKK22874.1 - 2.9e-12 46.8 0.3 3.2e-11 43.4 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KKK22874.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase CRC_subunit PF08624.5 KKK22875.1 - 3.3e-56 189.0 0.1 4.5e-56 188.6 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit His_Phos_1 PF00300.17 KKK22876.1 - 1.2e-11 44.9 0.6 2.1e-11 44.1 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF4528 PF15031.1 KKK22876.1 - 0.031 14.0 0.1 0.074 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) Homeobox PF00046.24 KKK22877.1 - 0.16 11.5 4.9 0.32 10.6 2.7 2.1 2 0 0 2 2 2 0 Homeobox domain Snf7 PF03357.16 KKK22889.1 - 9.7e-44 148.7 15.3 1.2e-43 148.4 10.6 1.1 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 KKK22889.1 - 0.002 17.6 5.8 0.002 17.6 4.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) Prefoldin_2 PF01920.15 KKK22889.1 - 0.01 15.6 7.8 0.08 12.7 0.0 3.5 2 1 1 3 3 2 0 Prefoldin subunit Y_phosphatase3C PF13348.1 KKK22889.1 - 0.018 15.1 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region Reo_sigmaC PF04582.7 KKK22889.1 - 0.018 14.2 3.4 0.12 11.5 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KKK22889.1 - 0.019 15.2 5.5 0.16 12.2 0.4 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.10 KKK22889.1 - 0.026 14.2 5.3 0.67 9.6 1.6 2.2 1 1 1 2 2 2 0 Sec34-like family DUF1395 PF07160.7 KKK22889.1 - 0.05 13.0 4.9 0.25 10.7 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) HHH_2 PF12826.2 KKK22889.1 - 0.05 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif IncA PF04156.9 KKK22889.1 - 0.21 11.1 5.0 0.86 9.1 0.5 2.3 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 KKK22889.1 - 0.28 10.0 6.9 0.4 9.5 4.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 KKK22889.1 - 0.81 10.1 3.5 2.8 8.4 0.0 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Mod_r PF07200.8 KKK22889.1 - 0.9 9.4 9.5 0.14 12.0 2.5 2.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF4094 PF13334.1 KKK22889.1 - 1.1 9.7 4.2 42 4.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) OmpH PF03938.9 KKK22889.1 - 1.1 9.1 12.2 2 8.3 6.4 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4337 PF14235.1 KKK22889.1 - 1.2 8.9 6.7 0.32 10.8 2.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FlaC_arch PF05377.6 KKK22889.1 - 1.3 8.9 4.7 26 4.8 0.9 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 KKK22889.1 - 1.9 6.8 8.5 1.3 7.3 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Drf_GBD PF06371.8 KKK22890.1 - 1.3e-16 60.5 1.9 3.6e-15 55.8 1.3 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Nramp PF01566.13 KKK22891.1 - 1.2e-93 313.7 21.5 1.2e-93 313.7 14.9 1.3 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Ribosomal_L6 PF00347.18 KKK22892.1 - 8.3e-25 87.0 0.1 1e-13 51.5 0.0 2.9 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 KKK22893.1 - 3.5e-53 180.6 0.8 7.3e-53 179.5 0.6 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Proteasome PF00227.21 KKK22894.1 - 2.8e-61 206.1 0.2 3.4e-61 205.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KKK22894.1 - 3.1e-14 51.9 0.2 7.1e-14 50.8 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature 4HBT PF03061.17 KKK22895.1 - 2.3e-09 37.2 0.1 4.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily CDK2AP PF09806.4 KKK22895.1 - 0.029 14.6 5.1 0.063 13.5 1.8 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DEAD PF00270.24 KKK22896.1 - 2.1e-41 141.2 0.0 7.1e-41 139.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK22896.1 - 2.9e-22 78.3 0.0 8.1e-22 76.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KKK22896.1 - 0.0028 16.5 0.0 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PMSI1 PF15322.1 KKK22896.1 - 0.11 11.5 1.8 0.21 10.6 1.3 1.4 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Glypican PF01153.14 KKK22896.1 - 1.9 6.9 8.0 7.8 4.9 2.5 2.1 2 0 0 2 2 2 0 Glypican RNA_polI_A34 PF08208.6 KKK22896.1 - 9.9 5.7 21.6 0.13 11.8 8.8 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 FtsJ PF01728.14 KKK22898.1 - 5.3e-55 186.2 0.0 7.4e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase NAD_binding_10 PF13460.1 KKK22899.1 - 5.6e-11 42.7 0.7 6.9e-11 42.4 0.5 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KKK22899.1 - 5.6e-05 22.4 0.3 0.00012 21.4 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 KKK22899.1 - 8.4e-05 22.1 0.0 0.00075 19.0 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK22899.1 - 0.00013 20.9 0.1 0.16 10.8 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.19 KKK22899.1 - 0.00025 21.3 0.1 0.0022 18.3 0.0 2.2 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain HIM1 PF08732.5 KKK22899.1 - 0.00062 18.3 0.0 0.00084 17.9 0.0 1.3 1 0 0 1 1 1 1 HIM1 DapB_N PF01113.15 KKK22899.1 - 0.037 13.9 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus UQ_con PF00179.21 KKK22900.1 - 8.2e-35 119.2 0.1 9.8e-35 119.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme APG12 PF04110.8 KKK22901.1 - 1.2e-30 105.5 0.0 2.2e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KKK22901.1 - 0.046 13.6 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like DUF2011 PF09428.5 KKK22902.1 - 2.3e-45 153.6 3.6 3.9e-45 152.9 2.5 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) LAMTOR PF15454.1 KKK22903.1 - 1e-24 86.5 0.4 1.7e-24 85.8 0.3 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator SOG2 PF10428.4 KKK22903.1 - 0.12 11.0 0.3 0.13 10.8 0.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein VHS PF00790.14 KKK22904.1 - 2.3e-24 85.6 0.0 5.6e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KKK22904.1 - 8.4e-12 44.9 1.4 1.7e-11 43.9 1.0 1.5 1 0 0 1 1 1 1 GAT domain ENTH PF01417.15 KKK22904.1 - 0.0039 17.0 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 ENTH domain BLVR PF06375.6 KKK22904.1 - 0.13 12.0 3.1 0.26 11.0 2.1 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) MIP-T3 PF10243.4 KKK22905.1 - 1 7.7 27.4 1.2 7.5 19.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRP38_assoc PF12871.2 KKK22905.1 - 3.5 8.2 88.6 53 4.4 37.8 2.7 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TFIIS_M PF07500.9 KKK22906.1 - 1.3e-22 80.0 0.0 3e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KKK22906.1 - 4.3e-19 69.1 0.0 8.1e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 KKK22906.1 - 6.2e-11 41.8 12.7 1.2e-10 40.9 8.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 KKK22906.1 - 0.017 15.3 0.3 0.1 12.8 0.2 2.4 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 KKK22906.1 - 0.18 11.1 4.9 0.32 10.3 3.4 1.4 1 0 0 1 1 1 0 PHD-finger HisKA PF00512.20 KKK22906.1 - 0.39 10.7 2.1 5.8 6.9 0.1 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Nucleo_P87 PF07267.6 KKK22907.1 - 5.8 5.4 15.4 7 5.1 10.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FF PF01846.14 KKK22908.1 - 3.4e-14 52.5 6.8 2.7e-10 40.0 0.1 3.7 3 0 0 3 3 3 3 FF domain WW PF00397.21 KKK22908.1 - 6.6e-09 35.4 3.5 6.6e-09 35.4 2.4 3.1 3 0 0 3 3 3 1 WW domain DUF4200 PF13863.1 KKK22908.1 - 4.1 7.3 30.6 1.1 9.2 6.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Tht1 PF04163.7 KKK22909.1 - 0.00076 18.0 7.3 0.0039 15.6 3.0 3.0 2 1 0 2 2 2 1 Tht1-like nuclear fusion protein Med2 PF11214.3 KKK22909.1 - 0.69 9.9 10.6 0.69 9.9 1.4 3.4 1 1 2 3 3 3 0 Mediator complex subunit 2 HrpA_pilin PF09589.5 KKK22909.1 - 3.3 8.1 9.9 0.64 10.4 2.5 2.6 3 0 0 3 3 3 0 HrpA pilus formation protein Gpi16 PF04113.9 KKK22911.1 - 2.8e-240 798.1 0.0 1.8e-237 788.8 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 KKK22912.1 - 1.6e-72 244.0 1.7 2e-72 243.7 1.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.16 KKK22912.1 - 0.037 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_13 PF13166.1 KKK22912.1 - 0.068 11.6 1.1 0.09 11.2 0.3 1.5 1 1 0 1 1 1 0 AAA domain Snf7 PF03357.16 KKK22912.1 - 0.23 10.8 5.1 0.18 11.1 1.9 2.0 2 1 0 2 2 2 0 Snf7 FAD_binding_1 PF00667.15 KKK22913.1 - 2.8e-62 210.0 0.0 5.3e-62 209.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KKK22913.1 - 5e-11 43.1 0.0 1.4e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KKK22913.1 - 6.9e-09 35.8 0.1 2.4e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KKK22913.1 - 5.5e-05 23.0 0.2 0.00018 21.4 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Dfp1_Him1_M PF08630.5 KKK22914.1 - 1.6e-40 137.7 0.0 3.5e-40 136.6 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KKK22914.1 - 8e-25 86.2 0.3 1.7e-24 85.2 0.2 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 KKK22914.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pantoate_transf PF02548.10 KKK22915.1 - 7.4e-107 356.3 0.9 8.7e-107 356.0 0.6 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KKK22915.1 - 1.2e-09 37.7 0.7 2.9e-09 36.5 0.5 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pyridox_ox_2 PF12900.2 KKK22916.1 - 1.3e-38 131.9 0.0 1.8e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M24 PF00557.19 KKK22917.1 - 6.8e-45 153.1 0.0 1.2e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KKK22917.1 - 9.7e-36 122.1 0.0 1.7e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.13 KKK22917.1 - 0.043 14.3 0.0 0.12 12.9 0.0 1.8 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain SIR2 PF02146.12 KKK22918.1 - 1.5e-19 70.4 0.0 1.9e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family DUF4231 PF14015.1 KKK22918.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Flavoprotein PF02441.14 KKK22919.1 - 1e-11 44.6 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein MFS_1 PF07690.11 KKK22920.1 - 2.5e-44 151.4 44.5 3.7e-44 150.8 30.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK22920.1 - 6.3e-16 57.9 34.4 1.2e-15 57.1 8.5 3.8 3 1 0 3 3 3 2 Sugar (and other) transporter DUF3624 PF12292.3 KKK22920.1 - 3.3 8.1 8.2 0.26 11.6 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) WD40 PF00400.27 KKK22928.1 - 3.4e-11 42.5 10.7 0.00055 19.7 0.0 7.0 8 0 0 8 8 8 3 WD domain, G-beta repeat LisH PF08513.6 KKK22928.1 - 9.6e-07 28.3 0.0 1.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 KKK22928.1 - 0.00026 20.7 0.0 0.0015 18.2 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A FEZ PF07763.8 KKK22929.1 - 0.027 14.1 4.6 0.05 13.3 3.2 1.3 1 0 0 1 1 1 0 FEZ-like protein IncA PF04156.9 KKK22929.1 - 0.045 13.3 6.1 0.016 14.8 2.3 1.6 2 0 0 2 2 2 0 IncA protein PspA_IM30 PF04012.7 KKK22929.1 - 0.052 12.9 3.6 0.91 8.8 0.1 2.2 1 1 0 2 2 2 0 PspA/IM30 family Baculo_PEP_C PF04513.7 KKK22929.1 - 0.058 13.2 0.5 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ERM PF00769.14 KKK22929.1 - 0.081 12.4 5.1 0.18 11.3 3.6 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ATG16 PF08614.6 KKK22929.1 - 0.09 12.5 6.4 0.22 11.3 4.4 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 KKK22929.1 - 0.096 11.7 2.5 0.14 11.1 1.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 WD40_alt PF14077.1 KKK22929.1 - 0.11 12.1 0.6 0.27 10.8 0.4 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif Cep57_MT_bd PF06657.8 KKK22929.1 - 0.21 11.5 3.6 0.41 10.6 2.5 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 TPR_MLP1_2 PF07926.7 KKK22929.1 - 0.22 11.2 4.8 0.48 10.1 3.3 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SPX PF03105.14 KKK22929.1 - 0.26 11.0 4.2 0.48 10.1 2.9 1.6 1 1 0 1 1 1 0 SPX domain FlaC_arch PF05377.6 KKK22929.1 - 0.8 9.6 3.2 20 5.1 0.4 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Lzipper-MIP1 PF14389.1 KKK22929.1 - 1.7 8.8 7.4 4.4 7.4 0.3 2.6 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.10 KKK22929.1 - 4.1 6.9 5.6 6.4 6.3 2.5 2.1 1 1 1 2 2 2 0 Septum formation initiator FlxA PF14282.1 KKK22929.1 - 6.9 6.6 9.0 18 5.3 0.4 2.4 1 1 1 2 2 2 0 FlxA-like protein Chorismate_bind PF00425.13 KKK22930.1 - 2.3e-88 295.8 0.0 3.3e-88 295.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KKK22930.1 - 3.2e-28 98.4 0.0 9.3e-26 90.5 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region DUF1751 PF08551.5 KKK22931.1 - 4.8e-22 78.1 4.1 6.2e-22 77.7 1.3 2.3 2 1 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KKK22931.1 - 8.9e-05 22.5 7.1 0.00067 19.6 4.9 2.0 1 1 0 1 1 1 1 Rhomboid family DUF4149 PF13664.1 KKK22931.1 - 1.2 9.2 8.9 1.2 9.2 2.5 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) L51_S25_CI-B8 PF05047.11 KKK22932.1 - 1e-21 76.4 0.0 1.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain tRNA-synt_1 PF00133.17 KKK22933.1 - 1.4e-37 128.9 0.0 5.8e-26 90.6 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KKK22933.1 - 2.1e-18 66.1 0.0 2.1e-11 43.1 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KKK22933.1 - 1.1e-14 54.4 0.2 2.7e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KKK22933.1 - 1.3e-07 31.0 0.0 3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain MMR_HSR1 PF01926.18 KKK22934.1 - 1.4e-06 28.2 0.0 8.1e-06 25.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATPase-cat_bd PF12156.3 KKK22934.1 - 0.00095 19.6 0.2 0.0027 18.2 0.2 1.7 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase DUF258 PF03193.11 KKK22934.1 - 0.013 14.6 0.0 0.073 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 KKK22934.1 - 0.031 14.7 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KKK22934.1 - 0.031 14.0 0.1 3.4 7.4 0.1 2.8 1 1 1 2 2 2 0 Dynamin family Telomere_Sde2 PF13019.1 KKK22935.1 - 1.3e-65 219.9 0.3 2.2e-65 219.2 0.2 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rotamase_2 PF13145.1 KKK22935.1 - 0.0076 16.8 0.9 0.015 15.9 0.6 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain S10_plectin PF03501.10 KKK22936.1 - 1.3e-41 140.3 0.1 1.8e-41 139.8 0.1 1.2 1 0 0 1 1 1 1 Plectin/S10 domain tRNA-synt_1c_C PF03950.13 KKK22936.1 - 0.039 13.6 0.0 0.049 13.3 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Peptidase_M20 PF01546.23 KKK22937.1 - 1.7e-20 73.3 0.1 2.2e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KKK22937.1 - 0.00042 20.0 0.0 0.00075 19.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KKK22937.1 - 0.027 14.2 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M28 HIT PF01230.18 KKK22938.1 - 1.1e-22 80.4 0.2 1.4e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KKK22938.1 - 6.9e-14 52.0 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KKK22938.1 - 3.2e-05 23.5 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Fungal_trans_2 PF11951.3 KKK22939.1 - 9.6e-12 44.1 0.0 2e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22939.1 - 6.4e-09 35.5 7.8 1.2e-08 34.6 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NADH-u_ox-rdase PF10785.4 KKK22952.1 - 6.5e-37 125.6 0.3 1.1e-36 124.9 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KKK22952.1 - 1.4e-33 114.4 0.1 2e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Ras PF00071.17 KKK22953.1 - 2e-65 219.1 0.1 2.3e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK22953.1 - 7.6e-19 68.3 0.0 1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK22953.1 - 7.1e-14 51.4 0.1 9.2e-14 51.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK22953.1 - 7.7e-07 28.7 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KKK22953.1 - 2.1e-06 27.0 0.0 2.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK22953.1 - 0.0046 16.8 0.0 0.0074 16.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK22953.1 - 0.015 14.5 0.0 0.073 12.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 KKK22953.1 - 0.025 14.7 0.0 5.8 7.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 KKK22953.1 - 0.026 13.7 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KKK22953.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KKK22953.1 - 0.13 11.8 0.7 0.29 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain NCA2 PF08637.5 KKK22954.1 - 7.7e-74 248.1 0.0 1.5e-73 247.2 0.0 1.5 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.8 KKK22955.1 - 1.4e-15 57.7 18.2 1.4e-15 57.7 12.6 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily dCMP_cyt_deam_1 PF00383.17 KKK22956.1 - 4.6e-25 87.2 0.0 5.9e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KKK22956.1 - 0.1 12.4 0.9 0.43 10.4 0.6 1.9 1 1 0 1 1 1 0 Bd3614-like deaminase PI3_PI4_kinase PF00454.22 KKK22957.1 - 3.3e-54 183.8 0.2 8e-54 182.5 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KKK22957.1 - 3.5e-50 170.9 3.1 9.1e-50 169.6 2.2 1.8 1 0 0 1 1 1 1 FAT domain UME PF08064.8 KKK22957.1 - 8.8e-41 138.1 0.2 5e-40 135.7 0.2 2.5 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 KKK22957.1 - 4e-14 51.7 0.0 1.4e-13 49.9 0.0 2.1 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 KKK22957.1 - 5.6e-05 22.6 1.2 0.6 9.7 0.0 3.7 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 KKK22957.1 - 0.012 16.1 3.4 7.9 7.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 KKK22957.1 - 0.013 15.6 1.6 4.4 7.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK22957.1 - 0.024 14.4 0.7 19 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK22957.1 - 0.08 13.6 0.2 2.8 8.7 0.1 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK22957.1 - 0.098 13.0 0.4 24 5.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.17 KKK22958.1 - 1.9e-15 56.2 0.0 3.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK22958.1 - 7.5e-10 38.6 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK22958.1 - 1.5e-08 34.3 0.0 2.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KKK22958.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DUF1777 PF08648.7 KKK22958.1 - 2.5 7.8 24.4 3.2 7.4 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) AAA PF00004.24 KKK22959.1 - 1.8e-62 209.4 0.0 8.2e-42 142.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK22959.1 - 3.1e-10 40.3 1.1 0.0024 17.9 0.0 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KKK22959.1 - 7.6e-07 28.9 1.2 0.0028 17.3 0.1 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KKK22959.1 - 1.8e-06 28.1 4.3 0.53 10.4 0.1 4.9 3 2 1 4 4 3 2 AAA domain AAA_28 PF13521.1 KKK22959.1 - 1.4e-05 25.1 0.0 0.092 12.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 KKK22959.1 - 5.2e-05 23.1 0.0 0.13 12.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KKK22959.1 - 5.6e-05 22.9 0.2 0.13 11.9 0.0 3.3 2 1 1 4 4 4 2 Archaeal ATPase TIP49 PF06068.8 KKK22959.1 - 0.00014 20.7 0.1 0.0073 15.0 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus RNA_helicase PF00910.17 KKK22959.1 - 0.00016 21.8 0.0 0.42 10.8 0.0 2.8 2 1 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 KKK22959.1 - 0.00022 20.6 5.5 0.76 9.1 0.0 4.2 2 2 1 3 3 3 1 AAA domain Rad17 PF03215.10 KKK22959.1 - 0.00025 19.8 0.0 0.00073 18.3 0.0 1.7 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KKK22959.1 - 0.00041 19.4 0.0 0.018 14.1 0.0 3.1 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KKK22959.1 - 0.00041 21.1 0.2 0.64 10.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK22959.1 - 0.00056 19.6 0.2 0.79 9.5 0.0 3.9 4 0 0 4 4 4 1 Part of AAA domain AAA_2 PF07724.9 KKK22959.1 - 0.00066 19.6 0.0 0.0025 17.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 KKK22959.1 - 0.0014 18.2 1.1 0.069 12.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KKK22959.1 - 0.0021 17.0 0.0 1.5 7.6 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KKK22959.1 - 0.0024 17.3 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 KKK22959.1 - 0.027 14.1 0.7 6.1 6.4 0.1 3.9 2 2 1 3 3 3 0 NACHT domain Sigma54_activ_2 PF14532.1 KKK22959.1 - 0.058 13.4 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 KKK22959.1 - 0.077 12.5 0.1 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KKK22959.1 - 0.095 11.8 0.5 2.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Swi3 PF07962.7 KKK22960.1 - 6.8e-32 108.9 0.6 1.3e-31 108.0 0.2 1.6 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 E1_dh PF00676.15 KKK22961.1 - 9.6e-114 379.1 0.1 1.2e-113 378.8 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KKK22961.1 - 0.0002 20.4 0.0 0.00039 19.4 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase OTU PF02338.14 KKK22962.1 - 4.2e-12 46.7 0.1 1.6e-11 44.8 0.1 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 KKK22962.1 - 0.0097 15.3 0.0 0.029 13.8 0.0 1.8 1 0 0 1 1 1 1 CUE domain MHYT PF03707.11 KKK22963.1 - 2.2e-10 40.4 20.2 4.7e-06 26.6 1.4 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Pyridoxal_deC PF00282.14 KKK22965.1 - 2.5e-78 263.1 0.0 3.3e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Abhydrolase_6 PF12697.2 KKK22972.1 - 3.2e-13 50.1 0.3 4.9e-13 49.4 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK22972.1 - 3.5e-10 39.8 0.0 9e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK22972.1 - 0.00016 21.4 0.0 0.00041 20.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KKK22972.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF3604 PF12228.3 KKK22972.1 - 0.22 9.6 0.0 0.32 9.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) phage_tail_N PF08400.5 KKK22973.1 - 0.049 13.3 0.1 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Prophage tail fibre N-terminal MDFI PF15316.1 KKK22973.1 - 2.9 7.8 9.8 0.47 10.4 1.2 2.1 2 0 0 2 2 2 0 MyoD family inhibitor Cohesin_load PF10345.4 KKK22974.1 - 8.3e-179 595.7 7.6 9.7e-179 595.4 5.3 1.0 1 0 0 1 1 1 1 Cohesin loading factor F-box PF00646.28 KKK22974.1 - 0.054 13.1 1.2 0.13 11.9 0.9 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 KKK22974.1 - 0.14 11.8 6.0 0.021 14.5 0.8 2.2 2 0 0 2 2 2 0 F-box-like DUF947 PF06102.7 KKK22975.1 - 1.9e-50 170.9 19.2 1.9e-50 170.9 13.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF947) NIF PF03031.13 KKK22977.1 - 6.2e-24 84.4 0.0 1.2e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RNA_pol_L_2 PF13656.1 KKK22978.1 - 8e-31 105.3 0.0 1.1e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KKK22978.1 - 2.2e-13 49.0 0.0 3.2e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.1 KKK22979.1 - 3.5e-07 30.6 0.2 4.3e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KKK22979.1 - 1.8e-05 24.4 0.5 3.7e-05 23.4 0.3 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK22979.1 - 6.2e-05 23.1 0.2 9.7e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Arb1 PF09692.5 KKK22982.1 - 8.8e-151 502.2 0.2 1e-150 502.0 0.1 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF600 PF04634.7 KKK22982.1 - 0.0086 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF600 IPK PF03770.11 KKK22983.1 - 1.9e-60 203.8 0.0 2.7e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase SBF PF01758.11 KKK22984.1 - 2.5e-49 167.2 8.5 2.5e-49 167.2 5.9 2.4 3 1 0 3 3 3 1 Sodium Bile acid symporter family DUF3671 PF12420.3 KKK22984.1 - 0.065 13.2 2.3 2.2 8.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF2061 PF09834.4 KKK22984.1 - 2.1 8.6 5.5 1.2 9.3 0.3 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2061) LMWPc PF01451.16 KKK22985.1 - 1.8e-29 102.8 0.0 2e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Toxin_1 PF00087.16 KKK22985.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Snake toxin FMN_red PF03358.10 KKK22986.1 - 2.9e-22 78.8 0.0 4.2e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase OPT PF03169.10 KKK22987.1 - 9.2e-120 400.9 42.2 1.1e-119 400.7 29.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ADH_zinc_N PF00107.21 KKK22988.1 - 4.5e-31 107.1 0.0 7.4e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK22988.1 - 1.1e-20 74.7 0.0 2.3e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK22988.1 - 6.8e-11 41.8 0.0 3.5e-10 39.6 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 KKK22988.1 - 0.024 14.5 0.4 0.15 12.0 0.0 2.5 3 1 0 3 3 3 0 Chaperonin 10 Kd subunit NAD_binding_10 PF13460.1 KKK22988.1 - 0.11 12.4 0.2 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF4207 PF13904.1 KKK22989.1 - 0.01 15.2 0.6 0.032 13.6 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Polysacc_deac_1 PF01522.16 KKK22990.1 - 1.1e-20 73.4 0.0 6.2e-20 71.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase Clp1 PF06807.9 KKK22990.1 - 2.1e-11 43.9 0.0 8.4e-07 28.9 0.0 2.8 3 1 0 3 3 3 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KKK22990.1 - 3.1e-07 30.1 0.0 3.3e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KKK22990.1 - 6.6e-05 22.5 0.0 0.00026 20.6 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KKK22990.1 - 7.1e-05 22.7 0.0 0.00035 20.5 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF2207 PF09972.4 KKK22990.1 - 0.015 13.9 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AAA_16 PF13191.1 KKK22990.1 - 0.017 15.1 0.0 0.056 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_35 PF14516.1 KKK22990.1 - 0.034 12.7 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 KKK22990.1 - 0.15 11.2 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit KilA-N PF04383.8 KKK22991.1 - 0.00039 20.0 0.0 0.0032 17.0 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain EF-1_beta_acid PF10587.4 KKK22991.1 - 0.019 15.1 6.2 0.11 12.6 4.3 2.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region TFIIA PF03153.8 KKK22991.1 - 9.7 5.9 15.4 18 5.1 10.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rho_GDI PF02115.12 KKK22992.1 - 3e-39 134.5 0.0 3.4e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor SF3b10 PF07189.6 KKK22993.1 - 1.1e-35 121.3 0.0 1.2e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) A_deamin PF02137.13 KKK22994.1 - 6.4e-45 153.9 0.0 2.4e-43 148.7 0.0 2.2 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain SLS PF14611.1 KKK22995.1 - 3.5e-53 180.1 0.0 6.4e-53 179.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator NT-C2 PF10358.4 KKK22995.1 - 1.7e-34 118.3 0.0 3e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3074 PF11274.3 KKK22997.1 - 4.2e-61 205.7 0.3 4.2e-61 205.7 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) FlaC_arch PF05377.6 KKK22997.1 - 0.99 9.3 3.1 18 5.3 0.1 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 KKK22998.1 - 0.022 13.8 1.9 0.025 13.6 1.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KKK22998.1 - 0.069 12.7 1.7 0.082 12.5 1.2 1.1 1 0 0 1 1 1 0 IncA protein DinB PF05163.7 KKK22998.1 - 0.089 12.4 0.9 0.11 12.1 0.6 1.1 1 0 0 1 1 1 0 DinB family Nop25 PF09805.4 KKK22998.1 - 0.35 10.9 9.0 0.51 10.4 6.2 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) AAA_13 PF13166.1 KKK22998.1 - 0.4 9.0 5.0 0.49 8.7 3.5 1.0 1 0 0 1 1 1 0 AAA domain XhlA PF10779.4 KKK22998.1 - 5.6 6.9 7.9 9.3 6.2 5.5 1.5 1 1 0 1 1 1 0 Haemolysin XhlA NUC130_3NT PF08158.7 KKK22999.1 - 2e-06 27.9 17.2 5.4 7.3 0.1 10.3 7 2 6 14 14 14 3 NUC130/3NT domain NAAA-beta PF15508.1 KKK22999.1 - 2.2e-05 24.7 0.0 7.9 6.9 0.0 5.8 2 2 4 7 7 7 2 beta subunit of N-acylethanolamine-hydrolyzing acid amidase PAH PF02671.16 KKK22999.1 - 4.3e-05 23.0 4.6 26 4.5 0.1 9.1 9 2 1 10 10 10 1 Paired amphipathic helix repeat DUF1732 PF08340.6 KKK22999.1 - 0.098 12.4 0.1 1.9 8.3 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1732) Glyco_hydro_3 PF00933.16 KKK23000.1 - 2.1e-96 322.4 0.0 3e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK23000.1 - 6.9e-55 186.0 0.2 1.7e-53 181.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK23000.1 - 7.1e-15 54.7 0.1 1.4e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_1 PF00170.16 KKK23001.1 - 0.0052 16.7 11.3 0.034 14.0 7.8 2.0 1 1 1 2 2 2 1 bZIP transcription factor PV-1 PF06637.6 KKK23001.1 - 0.36 9.3 4.8 0.54 8.7 3.4 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Scs3p PF10261.4 KKK23003.1 - 1.3e-57 194.6 5.5 1.3e-57 194.6 3.8 2.3 2 0 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM Man-6-P_recep PF02157.10 KKK23004.1 - 1.4e-09 37.3 0.0 2.1e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 KKK23004.1 - 8.3e-09 35.3 1.1 0.00038 20.2 0.1 2.4 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KKK23004.1 - 0.0094 15.2 0.0 0.043 13.0 0.0 2.0 2 1 0 2 2 2 1 Autophagy-related protein 27 ERG4_ERG24 PF01222.12 KKK23005.1 - 9.4e-157 521.9 4.6 1.1e-156 521.7 3.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KKK23005.1 - 5.7e-07 29.0 0.2 1.5e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Vps55 PF04133.9 KKK23005.1 - 0.0014 18.3 1.4 0.0053 16.5 1.0 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting 55 EBP PF05241.7 KKK23006.1 - 0.00027 20.0 0.3 0.00027 20.0 0.2 2.6 2 1 1 3 3 3 1 Emopamil binding protein Fungal_trans PF04082.13 KKK23007.1 - 3.7e-26 91.5 0.0 6.2e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23007.1 - 3.9e-09 36.2 12.1 6.1e-09 35.6 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 KKK23008.1 - 1.5e-23 82.8 1.6 1.5e-23 82.8 1.1 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KKK23008.1 - 1.1e-05 25.2 0.8 1.1e-05 25.2 0.5 2.1 3 0 0 3 3 3 1 Berberine and berberine like AAA_17 PF13207.1 KKK23009.1 - 0.00047 20.9 0.2 0.0066 17.2 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 KKK23009.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KKK23009.1 - 0.0029 16.5 0.0 0.011 14.6 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 KKK23009.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 KKK23009.1 - 0.066 13.5 0.1 0.42 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KKK23009.1 - 0.075 12.4 0.0 0.21 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain Peptidase_M29 PF02073.10 KKK23010.1 - 0.034 12.9 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) zf-UDP PF14569.1 KKK23010.1 - 0.044 13.5 0.5 0.28 10.9 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger HSP70 PF00012.15 KKK23013.1 - 6e-247 820.3 12.6 6.8e-247 820.2 8.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KKK23013.1 - 2.6e-17 62.4 2.0 3.3e-16 58.8 0.5 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KKK23013.1 - 0.005 15.7 1.4 0.019 13.7 0.9 1.9 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KKK23013.1 - 0.049 12.7 6.0 0.059 12.4 0.2 3.1 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KKK23013.1 - 6.6 6.5 7.4 5.5 6.8 0.8 3.4 2 2 0 2 2 2 0 Cell division protein FtsA DUF3154 PF11351.3 KKK23013.1 - 7 6.4 6.8 1.7 8.3 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3154) GTP_EFTU PF00009.22 KKK23014.1 - 2.1e-51 174.0 0.1 3.3e-51 173.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KKK23014.1 - 1.2e-14 54.1 4.5 2.5e-14 53.1 3.1 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 KKK23014.1 - 7.3e-08 32.3 0.0 2.9e-07 30.4 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KKK23014.1 - 9.8e-08 32.0 0.0 3.8e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 KKK23014.1 - 2.5e-06 27.5 0.0 9.8e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Gtr1_RagA PF04670.7 KKK23014.1 - 7.2e-05 22.0 0.1 0.00024 20.3 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KKK23014.1 - 0.00034 19.8 0.1 0.035 13.3 0.1 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KKK23014.1 - 0.0014 19.0 0.1 0.0073 16.7 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK23014.1 - 0.0046 16.2 0.2 1.3 8.2 0.0 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 KKK23014.1 - 0.024 13.9 0.6 0.72 9.1 0.2 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 KKK23014.1 - 0.03 13.3 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Septin Mannosyl_trans2 PF04188.8 KKK23025.1 - 3.8e-62 210.6 24.5 5.8e-62 210.0 17.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) PROL5-SMR PF15621.1 KKK23026.1 - 3.3 8.1 8.2 0.68 10.3 0.7 2.9 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Pro_CA PF00484.14 KKK23027.1 - 2.3e-30 105.6 1.5 1.8e-28 99.5 1.0 2.1 1 1 0 1 1 1 1 Carbonic anhydrase ODC_AZ PF02100.12 KKK23027.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme AMP-binding PF00501.23 KKK23028.1 - 1.2e-71 241.3 0.0 2.6e-71 240.2 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KKK23028.1 - 4.2e-58 196.1 0.0 8.9e-48 162.3 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.16 KKK23028.1 - 2.9e-15 56.3 0.0 5.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KKK23028.1 - 2.4e-11 43.7 0.0 5.2e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK23028.1 - 3.4e-08 34.3 0.0 1.5e-07 32.2 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 KKK23028.1 - 2.5e-05 24.3 0.0 6.2e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK23028.1 - 2.5e-05 23.1 0.1 6.8e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KKK23028.1 - 0.0028 16.5 0.0 0.036 12.9 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain Condensation PF00668.15 KKK23028.1 - 0.0038 16.1 0.0 0.0068 15.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain ECH PF00378.15 KKK23029.1 - 4.8e-45 153.5 0.0 5.4e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KKK23029.1 - 0.023 14.8 0.0 0.049 13.7 0.0 1.6 1 1 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region AMP-binding PF00501.23 KKK23030.1 - 2.6e-83 279.7 0.0 3.2e-77 259.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KKK23030.1 - 6.5e-74 248.4 4.6 1e-36 126.3 0.0 3.6 4 0 0 4 4 4 2 Condensation domain PP-binding PF00550.20 KKK23030.1 - 2e-28 98.4 0.1 1.3e-12 47.8 0.0 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK23030.1 - 4.6e-08 33.8 0.3 0.0045 17.9 0.1 3.4 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain AATase PF07247.7 KKK23030.1 - 0.12 10.8 2.4 4.1 5.8 0.0 2.6 3 0 0 3 3 3 0 Alcohol acetyltransferase DUF553 PF04473.7 KKK23030.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like domain Myb_DNA-bind_6 PF13921.1 KKK23038.1 - 3.2e-05 23.9 0.4 6.3e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK23038.1 - 0.14 12.1 0.3 0.29 11.2 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain COesterase PF00135.23 KKK23039.1 - 3.1e-93 313.2 0.0 4.2e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK23039.1 - 2.2e-07 30.6 0.2 1e-06 28.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK23039.1 - 7.1e-07 28.6 0.1 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK23039.1 - 0.00025 20.8 0.1 0.00054 19.7 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Alph_Pro_TM PF09608.5 KKK23040.1 - 0.085 12.3 0.5 0.12 11.8 0.3 1.1 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF4187 PF13821.1 KKK23041.1 - 3e-19 68.3 3.1 3e-19 68.3 2.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KKK23041.1 - 2.5e-08 33.5 0.4 3.6e-06 26.6 0.1 2.5 2 0 0 2 2 2 2 G-patch domain DUF1779 PF08680.5 KKK23041.1 - 7.4 6.3 8.6 0.84 9.4 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1779) BNR_2 PF13088.1 KKK23046.1 - 9.3e-09 34.9 0.2 4e-05 23.0 0.2 3.5 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.15 KKK23046.1 - 5.2e-06 25.5 15.2 0.17 11.8 0.2 5.1 5 0 0 5 5 5 4 BNR/Asp-box repeat Extensin_1 PF02095.10 KKK23047.1 - 0.98 9.5 5.6 0.23 11.5 1.3 2.0 2 0 0 2 2 2 0 Extensin-like protein repeat Pkinase PF00069.20 KKK23061.1 - 1.3e-50 172.0 0.0 2.4e-50 171.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23061.1 - 1.1e-25 90.2 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KKK23061.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK23061.1 - 0.029 14.0 1.0 0.053 13.2 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family U79_P34 PF03064.11 KKK23061.1 - 0.22 10.9 4.8 0.28 10.6 3.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pex16 PF08610.5 KKK23061.1 - 2.4 7.0 6.2 3.5 6.5 4.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Sod_Cu PF00080.15 KKK23062.1 - 1.3e-14 54.5 0.0 1.8e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 KKK23062.1 - 4.1e-13 49.2 0.0 7.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Aminotran_1_2 PF00155.16 KKK23063.1 - 4e-73 246.4 0.0 4.9e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-binding PF00249.26 KKK23063.1 - 0.099 12.7 0.1 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain TPR_1 PF00515.23 KKK23064.1 - 3.9e-13 48.3 6.1 4.1e-06 26.1 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KKK23064.1 - 2.6e-12 46.2 3.3 1.9e-08 33.8 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KKK23064.1 - 5.6e-12 44.6 4.8 0.00032 20.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK23064.1 - 6.1e-09 35.0 0.8 0.00037 20.0 0.0 4.6 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK23064.1 - 8.1e-08 32.0 0.3 0.00041 20.2 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK23064.1 - 7.7e-05 22.2 0.0 0.0012 18.4 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KKK23064.1 - 0.00014 21.6 0.1 0.66 9.8 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 KKK23064.1 - 0.00061 20.0 0.7 7.7 7.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat PB1 PF00564.19 KKK23064.1 - 0.00088 18.8 0.1 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_16 PF13432.1 KKK23064.1 - 0.0011 19.5 2.0 0.02 15.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK23064.1 - 0.021 15.4 0.3 0.95 10.2 0.0 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KKK23064.1 - 0.064 13.4 0.0 20 5.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Syntaxin-18_N PF10496.4 KKK23065.1 - 8.6e-08 31.9 3.5 1.4e-06 28.0 0.9 3.2 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KKK23065.1 - 0.00031 20.3 1.0 0.00031 20.3 0.7 2.4 2 0 0 2 2 2 1 SNARE domain Flavi_NS5 PF00972.15 KKK23065.1 - 0.018 12.9 0.0 0.026 12.4 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase Glyco_hydro_3 PF00933.16 KKK23066.1 - 7.2e-93 310.8 0.0 1e-92 310.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK23066.1 - 3.7e-49 167.3 0.0 7.3e-48 163.0 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK23066.1 - 2.6e-21 75.3 0.8 5e-21 74.4 0.6 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3574 PF12098.3 KKK23066.1 - 0.16 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) DUF572 PF04502.8 KKK23067.1 - 1e-25 90.6 0.0 1.2e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Cyt-b5 PF00173.23 KKK23068.1 - 1.5e-23 82.3 0.0 3.3e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Coatomer_E PF04733.9 KKK23075.1 - 2.6e-16 59.6 0.0 2.9e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.1 KKK23075.1 - 0.00086 19.1 0.8 0.0025 17.6 0.1 2.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK23075.1 - 0.0032 17.8 0.3 0.53 10.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KKK23075.1 - 0.0037 17.5 2.9 0.0044 17.3 0.7 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK23075.1 - 0.011 16.4 1.4 0.011 16.4 1.0 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KKK23075.1 - 0.028 14.6 0.3 0.15 12.3 0.0 2.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK23075.1 - 0.043 13.7 0.3 0.46 10.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KKK23075.1 - 0.049 13.7 0.0 11 6.2 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KKK23075.1 - 0.051 13.7 2.2 0.11 12.6 0.4 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 KKK23075.1 - 0.12 12.8 0.1 0.12 12.8 0.1 3.3 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK23075.1 - 0.34 11.6 6.7 1.9 9.3 0.3 3.3 2 1 2 4 4 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KKK23076.1 - 3.5e-48 164.0 0.0 4.4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23076.1 - 6.1e-27 94.3 0.0 8.8e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.12 KKK23077.1 - 0.00027 20.0 0.0 0.00052 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KKK23077.1 - 0.00072 18.7 0.0 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain P4Ha_N PF08336.6 KKK23077.1 - 0.11 12.2 0.6 0.19 11.5 0.4 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PNP_UDP_1 PF01048.15 KKK23078.1 - 4e-14 52.1 0.0 7.3e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily ABC_tran PF00005.22 KKK23079.1 - 3.2e-46 157.0 0.0 6.9e-28 97.6 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK23079.1 - 1.1e-32 113.6 18.4 1.7e-16 60.4 2.5 4.6 5 0 0 5 5 5 2 ABC transporter transmembrane region SMC_N PF02463.14 KKK23079.1 - 5.8e-10 38.7 0.5 0.075 12.2 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KKK23079.1 - 1.5e-05 24.2 0.0 0.033 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KKK23079.1 - 1.8e-05 25.1 0.0 0.0027 18.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KKK23079.1 - 7.7e-05 22.1 0.1 0.17 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KKK23079.1 - 0.00013 21.4 0.5 0.53 9.8 0.1 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 KKK23079.1 - 0.00015 21.6 2.6 0.17 11.6 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function DUF87 T2SE PF00437.15 KKK23079.1 - 0.00023 20.1 0.0 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 KKK23079.1 - 0.00083 18.8 0.4 0.53 9.6 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 KKK23079.1 - 0.0011 19.0 1.1 0.27 11.1 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK23079.1 - 0.0012 19.0 0.0 2.8 8.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KKK23079.1 - 0.0021 18.0 0.1 0.4 10.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 KKK23079.1 - 0.0035 17.3 1.7 12 5.7 0.0 4.1 5 0 0 5 5 5 0 AAA domain Zeta_toxin PF06414.7 KKK23079.1 - 0.0049 15.9 0.0 1.2 8.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 KKK23079.1 - 0.0052 16.2 0.0 0.94 8.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 KKK23079.1 - 0.0069 16.8 0.1 5.3 7.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein DUF2275 PF10039.4 KKK23079.1 - 0.012 15.5 0.8 0.02 14.7 0.0 1.7 2 0 0 2 2 1 0 Predicted integral membrane protein (DUF2275) DUF2075 PF09848.4 KKK23079.1 - 0.045 12.7 0.0 0.66 8.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 KKK23079.1 - 0.064 12.9 0.4 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 KKK23079.1 - 0.078 11.5 0.3 0.92 8.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.18 KKK23079.1 - 1.7 7.9 3.4 10 5.4 0.0 2.7 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain UPF0261 PF06792.6 KKK23080.1 - 3.7e-141 470.2 1.6 5e-141 469.8 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 KKK23080.1 - 1.3e-133 444.0 0.6 2.5e-133 443.1 0.4 1.5 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 KKK23080.1 - 0.01 15.0 0.1 0.02 14.0 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ABC2_membrane PF01061.19 KKK23081.1 - 1.8e-82 275.5 62.3 2.4e-43 147.7 17.5 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KKK23081.1 - 6.3e-36 123.7 0.0 1.1e-16 61.3 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KKK23081.1 - 2.3e-31 107.5 1.9 7.4e-26 89.8 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KKK23081.1 - 9.2e-16 57.7 0.2 3.1e-15 56.0 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KKK23081.1 - 2.8e-08 33.1 41.9 7.3e-05 21.9 15.7 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KKK23081.1 - 4.6e-08 32.6 0.0 0.00089 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK23081.1 - 0.00017 22.3 0.0 0.46 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KKK23081.1 - 0.00021 20.5 0.1 0.0011 18.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KKK23081.1 - 0.00031 20.6 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KKK23081.1 - 0.00041 19.8 1.6 0.013 15.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KKK23081.1 - 0.00049 20.1 1.3 0.03 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KKK23081.1 - 0.00054 19.1 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.14 KKK23081.1 - 0.00059 19.3 2.0 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KKK23081.1 - 0.0051 16.5 0.4 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KKK23081.1 - 0.017 15.4 0.1 0.35 11.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 KKK23081.1 - 0.02 15.0 0.2 0.8 9.8 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KKK23081.1 - 0.032 14.5 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KKK23081.1 - 0.044 13.4 1.4 2.9 7.5 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 KKK23081.1 - 0.068 13.1 0.0 0.73 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KKK23081.1 - 0.17 11.0 0.2 5.4 6.1 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 KKK23081.1 - 0.37 10.1 2.2 9.9 5.4 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 KKK23081.1 - 0.54 9.8 3.1 1.8 8.1 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Fungal_trans PF04082.13 KKK23082.1 - 1.5e-07 30.6 0.7 1.5e-07 30.6 0.5 1.8 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23082.1 - 2.2e-06 27.4 8.2 4.2e-06 26.5 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ala_racemase_N PF01168.15 KKK23084.1 - 3.1e-24 85.7 0.1 3.8e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 KKK23084.1 - 7.3e-19 67.7 0.0 1.4e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.10 KKK23084.1 - 0.0068 15.4 0.4 0.2 10.6 0.2 2.1 2 0 0 2 2 2 2 Serine dehydratase alpha chain Peptidase_S28 PF05577.7 KKK23085.1 - 5.3e-47 160.3 6.6 1.3e-45 155.8 4.6 2.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 AAA_12 PF13087.1 KKK23086.1 - 3.7e-32 111.3 0.0 2e-30 105.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK23086.1 - 3.3e-29 102.1 0.4 1e-28 100.5 0.3 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK23086.1 - 1e-08 34.8 0.1 3.4e-08 33.1 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KKK23086.1 - 3.5e-06 26.7 0.0 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KKK23086.1 - 0.0016 17.4 0.1 0.033 13.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KKK23086.1 - 0.0037 17.2 0.6 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ResIII PF04851.10 KKK23086.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 KKK23086.1 - 0.045 13.8 1.0 0.2 11.8 0.0 2.6 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain Ldh_1_N PF00056.18 KKK23087.1 - 8.9e-26 90.3 0.4 3.4e-23 82.0 0.3 2.2 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KKK23087.1 - 4.4e-23 81.8 0.0 6.6e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.12 KKK23087.1 - 0.0025 18.2 0.3 0.011 16.1 0.2 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_4 PF02056.11 KKK23087.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.5 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase ThiF PF00899.16 KKK23087.1 - 0.045 13.5 0.2 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 KKK23087.1 - 0.11 11.9 0.2 0.37 10.2 0.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_12 PF08242.7 KKK23088.1 - 6.1e-14 52.2 0.0 2e-13 50.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK23088.1 - 2.1e-13 50.3 0.0 4.2e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK23088.1 - 7.5e-13 48.7 0.1 1e-11 45.1 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK23088.1 - 5.1e-12 46.0 0.0 2.4e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK23088.1 - 6.5e-10 39.5 0.0 2.2e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK23088.1 - 2.3e-09 37.0 0.0 3.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK23088.1 - 5.1e-08 32.3 0.0 2.6e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KKK23088.1 - 2e-06 27.7 0.0 5.9e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF3419 PF11899.3 KKK23088.1 - 7.2e-05 21.6 0.0 0.00015 20.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) MTS PF05175.9 KKK23088.1 - 0.00084 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 KKK23088.1 - 0.0017 19.1 0.0 0.056 14.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 KKK23088.1 - 0.0026 17.4 0.0 0.31 10.6 0.0 2.4 2 1 0 2 2 2 1 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.12 KKK23088.1 - 0.0059 15.6 0.0 0.14 11.0 0.0 2.4 1 1 1 3 3 3 1 NNMT/PNMT/TEMT family CMAS PF02353.15 KKK23088.1 - 0.048 12.7 0.0 0.14 11.2 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase NMO PF03060.10 KKK23089.1 - 2.4e-33 115.6 2.3 1.1e-25 90.5 0.4 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KKK23089.1 - 3.9e-09 35.8 0.0 3.4e-05 22.9 1.1 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KKK23089.1 - 2.5e-06 26.5 1.0 3.7e-06 26.0 0.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KKK23089.1 - 0.0042 16.0 0.5 0.0067 15.3 0.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KKK23089.1 - 0.011 14.7 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.9 KKK23089.1 - 0.096 11.7 0.1 0.23 10.5 0.1 1.5 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KKK23089.1 - 0.11 11.7 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein Stk19 PF10494.4 KKK23090.1 - 2.8e-79 266.0 0.0 3.3e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 NmrA PF05368.8 KKK23092.1 - 1.6e-38 132.2 0.0 1.7e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK23092.1 - 6.8e-09 35.9 0.0 1.5e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 KKK23092.1 - 0.00015 21.7 0.1 0.0032 17.4 0.1 2.2 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.14 KKK23092.1 - 0.00029 19.6 0.0 0.00038 19.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK23092.1 - 0.00055 19.4 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KKK23092.1 - 0.018 14.9 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 KKK23092.1 - 0.019 14.9 0.3 0.032 14.1 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase HPP PF04982.8 KKK23094.1 - 2.7e-34 117.5 11.8 2.7e-34 117.5 8.2 1.4 2 0 0 2 2 2 1 HPP family Ycf66_N PF07444.6 KKK23094.1 - 0.081 12.6 3.1 0.29 10.8 0.3 2.6 2 0 0 2 2 2 0 Ycf66 protein N-terminus DUF939 PF06081.6 KKK23094.1 - 0.91 9.3 8.0 2.2 8.1 5.6 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF939) Methyltransf_3 PF01596.12 KKK23095.1 - 8.4e-14 51.1 0.0 1.1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KKK23095.1 - 6.4e-12 46.2 0.0 9.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK23095.1 - 0.00087 19.3 0.2 0.0023 17.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KKK23095.1 - 0.036 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase DUF2119 PF09892.4 KKK23095.1 - 0.067 12.4 0.0 0.71 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) GFO_IDH_MocA PF01408.17 KKK23096.1 - 5.8e-25 88.1 0.0 9.5e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KKK23096.1 - 1.4e-16 60.3 0.0 2.3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KKK23096.1 - 0.00018 21.8 0.0 0.00035 20.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 KKK23096.1 - 0.00053 19.9 0.0 0.00092 19.1 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KKK23096.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Endonuclease_NS PF01223.18 KKK23097.1 - 3.9e-60 203.0 0.0 5.5e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF2722 PF10846.3 KKK23097.1 - 0.079 11.9 2.6 0.11 11.5 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Ifi-6-16 PF06140.8 KKK23098.1 - 0.00013 21.6 24.5 0.00013 21.6 17.0 2.1 2 1 0 2 2 2 1 Interferon-induced 6-16 family Fungal_trans_2 PF11951.3 KKK23099.1 - 0.001 17.7 0.0 0.002 16.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KKK23100.1 - 6.5e-76 255.7 26.2 7.9e-76 255.4 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK23100.1 - 7.4e-18 64.3 50.1 1.5e-16 60.0 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 KKK23101.1 - 1.3e-47 161.5 0.1 2.6e-22 79.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KKK23101.1 - 2.1e-20 72.3 2.0 2.1e-20 72.3 1.4 2.9 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 KKK23101.1 - 7.1e-19 68.8 0.8 0.00058 19.9 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KKK23101.1 - 7.3e-11 41.7 0.4 0.012 14.8 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KKK23101.1 - 1.5e-08 35.2 3.2 0.031 14.6 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 KKK23101.1 - 1.7e-08 33.8 0.2 0.00063 19.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KKK23101.1 - 2.6e-06 26.7 0.0 0.0031 16.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK23101.1 - 8.4e-06 25.9 0.0 0.18 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KKK23101.1 - 1.6e-05 25.3 0.0 0.035 14.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 KKK23101.1 - 2.9e-05 24.1 0.3 0.14 12.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 KKK23101.1 - 3.5e-05 23.5 0.1 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KKK23101.1 - 4.5e-05 23.7 0.1 0.046 14.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 KKK23101.1 - 7.3e-05 21.7 0.0 0.06 12.1 0.0 3.1 2 1 0 2 2 2 1 NB-ARC domain MMR_HSR1 PF01926.18 KKK23101.1 - 7.7e-05 22.6 0.0 0.16 11.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 KKK23101.1 - 0.00017 21.7 0.5 1.6 8.9 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA PF00004.24 KKK23101.1 - 0.0002 21.5 0.0 0.9 9.7 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KKK23101.1 - 0.00024 20.8 0.0 0.23 11.0 0.0 2.9 3 0 0 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 KKK23101.1 - 0.0003 20.8 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK23101.1 - 0.00035 21.3 0.0 1.2 9.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KKK23101.1 - 0.00041 20.2 1.2 0.31 10.9 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 KKK23101.1 - 0.00042 19.8 1.1 0.66 9.3 0.2 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_14 PF13173.1 KKK23101.1 - 0.00044 20.1 0.0 1.1 9.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KKK23101.1 - 0.0011 18.6 0.2 1.4 8.6 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 KKK23101.1 - 0.0021 17.1 1.0 0.22 10.5 0.0 3.0 5 0 0 5 5 4 1 AAA ATPase domain MobB PF03205.9 KKK23101.1 - 0.0027 17.4 0.1 0.15 11.7 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KKK23101.1 - 0.0027 17.5 0.4 0.29 11.0 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KKK23101.1 - 0.0038 16.6 0.0 0.96 8.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.1 KKK23101.1 - 0.0042 15.6 0.2 5.3 5.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 KKK23101.1 - 0.026 14.3 3.3 4.3 7.1 0.0 3.7 4 1 1 5 5 4 0 Dynamin family DAP3 PF10236.4 KKK23101.1 - 0.026 13.4 0.8 4.2 6.2 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF87 PF01935.12 KKK23101.1 - 0.038 13.7 1.2 7.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 KKK23101.1 - 0.039 13.4 0.0 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ras PF00071.17 KKK23101.1 - 0.043 13.2 0.0 3.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Ras family NTPase_1 PF03266.10 KKK23101.1 - 0.056 13.1 0.1 7.3 6.2 0.1 2.6 2 0 0 2 2 2 0 NTPase DUF2813 PF11398.3 KKK23101.1 - 0.076 12.0 2.1 6 5.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) FeoB_N PF02421.13 KKK23101.1 - 0.096 11.9 0.1 5 6.3 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KKK23101.1 - 0.15 11.5 0.8 9.4 5.7 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KKK23101.1 - 0.79 9.2 4.5 9.5 5.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain zf-C3HC4_2 PF13923.1 KKK23102.1 - 4.5e-08 32.9 14.5 1.8e-05 24.6 2.3 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK23102.1 - 1.8e-05 24.4 12.6 0.00073 19.3 3.6 2.7 2 1 0 2 2 2 2 Ring finger domain FYVE PF01363.16 KKK23102.1 - 0.00056 19.7 10.1 0.0057 16.5 2.8 3.1 2 1 1 3 3 3 1 FYVE zinc finger zf-RING_5 PF14634.1 KKK23102.1 - 0.0006 19.4 7.7 0.0006 19.4 5.3 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK23102.1 - 0.00097 18.7 3.5 0.00097 18.7 2.4 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KKK23102.1 - 0.0019 17.8 2.1 0.0019 17.8 1.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 KKK23102.1 - 0.0053 15.9 7.1 0.0053 15.9 4.9 3.6 2 2 1 3 3 3 2 Rtf2 RING-finger zf-C3HC4_3 PF13920.1 KKK23102.1 - 0.0092 15.6 7.3 0.0092 15.6 5.1 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KKK23102.1 - 0.77 9.3 4.8 4.4 6.9 3.3 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Atg14 PF10186.4 KKK23102.1 - 4.1 6.2 14.8 9.9 5.0 10.3 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-CCCH PF00642.19 KKK23103.1 - 1.8e-05 24.2 0.9 1.8e-05 24.2 0.6 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glucosamine_iso PF01182.15 KKK23117.1 - 1.2e-58 198.1 0.0 1.4e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Na_H_Exchanger PF00999.16 KKK23118.1 - 3.5e-70 236.4 46.6 4.6e-70 236.0 32.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.21 KKK23118.1 - 0.014 15.5 0.0 0.2 11.8 0.0 2.6 2 1 0 2 2 2 0 Universal stress protein family GFA PF04828.9 KKK23119.1 - 3.4e-11 42.9 1.6 5.3e-11 42.3 1.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Mod_r PF07200.8 KKK23120.1 - 1.4e-09 37.9 3.5 2e-09 37.5 2.4 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein EF-hand_like PF09279.6 KKK23120.1 - 0.23 11.5 1.0 0.68 9.9 0.1 2.1 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Ank_5 PF13857.1 KKK23121.1 - 5.3e-11 42.3 0.0 3.7e-08 33.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK23121.1 - 8.4e-10 38.8 0.1 1e-05 25.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KKK23121.1 - 6.3e-06 26.4 0.2 4.1e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KKK23121.1 - 1.5e-05 24.7 0.5 0.00016 21.5 0.1 2.6 2 1 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 KKK23121.1 - 0.00013 21.5 1.6 0.004 16.9 0.1 3.2 3 1 0 3 3 3 1 Ankyrin repeat YejG PF13989.1 KKK23121.1 - 0.0066 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 YejG-like protein Got1 PF04178.7 KKK23122.1 - 4.2e-30 104.2 15.8 2.2e-29 101.9 10.9 1.9 1 1 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KKK23122.1 - 0.0017 17.3 0.0 0.0026 16.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M50 tRNA_lig_CPD PF08302.6 KKK23123.1 - 1.8e-89 299.3 0.0 2.5e-89 298.8 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 KKK23123.1 - 3.3e-69 232.7 0.5 2.2e-68 230.0 0.3 2.4 1 1 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 KKK23123.1 - 1.8e-52 177.5 0.0 3.1e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 KKK23123.1 - 0.054 13.3 0.0 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain Mito_carr PF00153.22 KKK23124.1 - 2.6e-42 142.4 0.8 5.2e-20 70.9 0.1 2.4 3 0 0 3 3 3 2 Mitochondrial carrier protein HLH PF00010.21 KKK23125.1 - 1.2e-12 47.2 0.0 3.6e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain La PF05383.12 KKK23127.1 - 1.2e-19 69.8 0.4 2.3e-19 68.9 0.3 1.4 1 0 0 1 1 1 1 La domain TYW3 PF02676.9 KKK23128.1 - 4.4e-76 254.5 0.0 5.5e-76 254.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 RRM_6 PF14259.1 KKK23129.1 - 0.019 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2461 PF09365.5 KKK23130.1 - 1.2e-77 260.0 0.0 1.7e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) 4HBT PF03061.17 KKK23131.1 - 0.0024 17.9 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily TRI12 PF06609.8 KKK23132.1 - 1.1e-37 129.5 25.0 1.4e-37 129.2 17.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KKK23132.1 - 3.8e-16 58.7 56.6 3.8e-16 58.7 39.2 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK23132.1 - 5.5e-08 31.8 15.4 5.5e-08 31.8 10.7 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.16 KKK23132.1 - 0.00019 21.0 6.2 0.00019 21.0 4.3 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus ARPC4 PF05856.7 KKK23133.1 - 1.2e-75 252.6 4.1 1.3e-75 252.4 2.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 KKK23134.1 - 1.7e-54 184.7 0.1 2.2e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK23134.1 - 1.5e-14 54.1 2.7 1.4e-13 50.9 1.9 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KKK23134.1 - 2.8e-11 42.6 0.1 1.2e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Ferritin_2 PF13668.1 KKK23135.1 - 2.2e-05 24.3 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Pec_lyase_C PF00544.14 KKK23136.1 - 1.7e-12 47.2 1.7 2.9e-12 46.4 1.2 1.4 1 0 0 1 1 1 1 Pectate lyase Strep_his_triad PF04270.8 KKK23141.1 - 0.86 9.3 3.3 17 5.2 0.0 2.9 3 0 0 3 3 3 0 Streptococcal histidine triad protein FAD_binding_4 PF01565.18 KKK23142.1 - 4.3e-14 52.1 0.0 6.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_25 PF01183.15 KKK23143.1 - 1.9e-23 83.2 0.7 2.6e-22 79.4 0.0 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 25 Methyltransf_23 PF13489.1 KKK23144.1 - 3.8e-22 78.7 0.0 5.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK23144.1 - 6.4e-11 42.6 0.0 4.9e-10 39.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK23144.1 - 7.9e-11 42.3 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK23144.1 - 1.4e-10 40.9 0.0 1.9e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK23144.1 - 1.7e-09 38.2 0.0 5.1e-08 33.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK23144.1 - 0.00021 21.6 0.0 0.00088 19.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KKK23144.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KKK23144.1 - 0.0023 17.1 0.0 0.036 13.1 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 KKK23144.1 - 0.0048 16.1 0.0 0.0095 15.1 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_26 PF13659.1 KKK23144.1 - 0.0048 16.9 0.0 0.015 15.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KKK23144.1 - 0.0096 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KKK23144.1 - 0.0097 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KKK23144.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 KKK23144.1 - 0.026 14.5 0.0 0.05 13.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase PLA2_B PF01735.13 KKK23145.1 - 3.7e-183 609.1 1.1 4.3e-183 608.9 0.8 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3425 PF11905.3 KKK23146.1 - 8.5e-21 74.2 0.2 1.5e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KKK23146.1 - 0.019 14.8 11.2 0.034 14.0 7.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor Methyltransf_2 PF00891.13 KKK23147.1 - 4.1e-34 117.8 0.0 1.8e-33 115.7 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase HTH_27 PF13463.1 KKK23147.1 - 0.0043 17.3 0.1 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain Dimerisation PF08100.6 KKK23147.1 - 0.035 13.9 0.2 0.16 11.8 0.1 2.1 1 1 0 1 1 1 0 Dimerisation domain PIG-L PF02585.12 KKK23149.1 - 6.9e-17 62.1 0.2 1.9e-16 60.7 0.2 1.7 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase FA_hydroxylase PF04116.8 KKK23150.1 - 2.4e-17 63.3 10.1 2.4e-17 63.3 7.0 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily NmrA PF05368.8 KKK23152.1 - 1.1e-35 123.0 0.0 1.4e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK23152.1 - 9.8e-12 45.2 0.1 1.5e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK23152.1 - 2.7e-07 29.6 0.0 3.7e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KKK23152.1 - 0.00016 21.6 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 KKK23152.1 - 0.00046 19.6 0.0 0.00074 19.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KKK23152.1 - 0.0024 17.7 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KKK23152.1 - 0.017 15.3 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KKK23152.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 KKK23152.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FGGY_N PF00370.16 KKK23161.1 - 8e-68 228.3 0.0 1.1e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KKK23161.1 - 1.9e-59 200.6 2.2 8.1e-58 195.3 1.5 2.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MIP PF00230.15 KKK23162.1 - 5.4e-54 183.0 5.3 7e-54 182.6 3.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2631 PF10939.3 KKK23162.1 - 0.13 12.0 0.6 5 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) ABC2_membrane PF01061.19 KKK23163.1 - 4e-76 254.8 51.3 1.8e-45 154.7 11.3 3.9 3 1 0 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.22 KKK23163.1 - 7.1e-39 133.2 0.0 1.6e-18 67.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KKK23163.1 - 3.4e-30 103.7 0.1 5.4e-28 96.6 0.0 3.3 3 0 0 3 3 3 1 CDR ABC transporter AAA_25 PF13481.1 KKK23163.1 - 2.8e-07 30.1 0.0 0.0028 17.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK23163.1 - 3.4e-05 24.0 0.1 0.094 12.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KKK23163.1 - 0.00023 21.0 0.1 0.76 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.4 KKK23163.1 - 0.00031 20.2 0.4 0.51 9.8 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KKK23163.1 - 0.0005 20.1 0.2 0.2 11.6 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 KKK23163.1 - 0.00052 19.4 1.0 0.29 10.5 0.4 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KKK23163.1 - 0.00063 18.9 0.4 0.0091 15.1 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KKK23163.1 - 0.0019 18.4 0.1 2.7 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KKK23163.1 - 0.0024 17.3 0.9 0.084 12.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KKK23163.1 - 0.0034 17.3 1.2 0.38 10.6 0.5 2.5 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KKK23163.1 - 0.0041 16.8 0.0 0.31 10.6 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 KKK23163.1 - 0.0046 16.6 0.6 3 7.4 0.2 2.4 2 0 0 2 2 2 2 NACHT domain ABC_trans_N PF14510.1 KKK23163.1 - 0.0082 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_17 PF13207.1 KKK23163.1 - 0.0097 16.7 0.0 1.5 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK23163.1 - 0.039 13.7 0.9 6.8 6.5 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 KKK23163.1 - 0.079 12.9 0.0 0.87 9.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KKK23163.1 - 0.12 12.5 0.1 35 4.5 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KKK23163.1 - 0.18 11.4 1.0 5.4 6.6 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KKK23163.1 - 0.19 12.2 0.0 3.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 KKK23163.1 - 0.27 10.2 0.4 13 4.7 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin Peptidase_M28 PF04389.12 KKK23164.1 - 3.1e-35 121.5 0.0 5.4e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KKK23164.1 - 3.9e-16 58.5 0.0 8.3e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 KKK23164.1 - 0.017 13.9 0.0 0.069 11.9 0.0 2.0 3 1 0 3 3 3 0 M42 glutamyl aminopeptidase Amino_oxidase PF01593.19 KKK23165.1 - 3.5e-23 82.3 0.0 4.8e-22 78.6 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KKK23165.1 - 3.4e-14 52.6 0.0 1.3e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK23165.1 - 1e-08 34.4 0.0 3.4e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK23165.1 - 0.00033 19.6 0.0 0.0037 16.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KKK23165.1 - 0.0008 19.7 0.0 0.19 12.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK23165.1 - 0.0021 17.2 0.1 0.0047 16.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK23165.1 - 0.0036 16.4 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KKK23165.1 - 0.0052 16.5 0.1 0.023 14.4 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK23165.1 - 0.018 14.8 0.1 0.081 12.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK23165.1 - 0.036 12.5 0.0 0.12 10.8 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.14 KKK23165.1 - 0.082 12.0 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 GMC oxidoreductase zf-CCCH_2 PF14608.1 KKK23166.1 - 1.4e-07 31.2 60.3 0.00013 21.7 9.8 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Mago-bind PF09282.5 KKK23167.1 - 8.7e-14 50.7 5.3 1.5e-13 49.9 3.7 1.4 1 0 0 1 1 1 1 Mago binding UCR_UQCRX_QCR9 PF05365.7 KKK23168.1 - 1.2e-26 92.1 1.3 1.7e-26 91.6 0.9 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Glyco_hydro_cc PF11790.3 KKK23169.1 - 7e-63 212.2 1.3 8.3e-63 211.9 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Choline_transpo PF04515.7 KKK23169.1 - 0.081 11.6 0.8 0.11 11.1 0.4 1.4 1 1 0 1 1 1 0 Plasma-membrane choline transporter DUF3243 PF11588.3 KKK23169.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) zf-UBR PF02207.15 KKK23170.1 - 5.1e-17 61.3 15.4 1.3e-16 60.0 10.7 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 KKK23170.1 - 0.00013 21.6 1.0 0.00013 21.6 0.7 4.7 4 1 0 4 4 4 1 Ring finger domain ClpS PF02617.12 KKK23170.1 - 0.0083 15.8 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS RED_N PF07808.8 KKK23171.1 - 3.4e-05 23.1 1.3 3.4e-05 23.1 0.9 2.2 2 1 0 2 2 2 1 RED-like protein N-terminal region GvpG PF05120.7 KKK23171.1 - 0.043 13.6 1.7 0.077 12.8 0.4 2.0 2 0 0 2 2 2 0 Gas vesicle protein G Pyr_redox_3 PF13738.1 KKK23200.1 - 1.2e-23 84.2 0.0 2.1e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK23200.1 - 6.7e-13 47.6 0.0 1.9e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KKK23200.1 - 1.1e-07 32.0 0.0 4.2e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK23200.1 - 1.1e-05 25.2 0.3 8.5e-05 22.3 0.0 2.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KKK23200.1 - 1.2e-05 24.4 0.0 7.5e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK23200.1 - 2e-05 24.4 0.9 0.00014 21.8 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK23200.1 - 0.00051 19.1 0.8 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.2 KKK23200.1 - 0.046 12.7 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK23200.1 - 0.06 13.7 0.5 7.3 7.0 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK23200.1 - 0.085 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KKK23200.1 - 0.19 10.1 0.0 2.1 6.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.13 KKK23201.1 - 8.9e-28 96.8 4.2 1.5e-27 96.1 2.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KKK23201.1 - 2.5e-07 30.5 13.7 0.0018 18.4 0.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK23201.1 - 9.9e-07 28.7 14.1 0.004 17.4 0.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KKK23201.1 - 0.38 10.7 0.1 0.38 10.7 0.0 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK23201.1 - 7 7.1 11.1 5.4 7.4 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger double domain SnoaL PF07366.7 KKK23204.1 - 0.00014 21.4 0.0 0.0003 20.3 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KKK23204.1 - 0.0022 18.3 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain TFIIA_gamma_C PF02751.9 KKK23205.1 - 5.4e-27 93.3 2.7 7.7e-27 92.8 1.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KKK23205.1 - 3.3e-26 90.6 0.2 4.6e-26 90.1 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ThiF PF00899.16 KKK23207.1 - 3.2e-53 179.1 0.0 7.9e-31 106.6 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KKK23207.1 - 1.8e-40 136.3 0.8 2.7e-26 90.8 0.2 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KKK23207.1 - 1e-38 132.3 0.0 2.5e-38 131.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KKK23207.1 - 2.1e-24 84.6 2.3 2e-21 75.0 0.3 2.6 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Pkinase PF00069.20 KKK23207.1 - 2.4e-15 56.4 0.0 4.2e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GST_N_2 PF13409.1 KKK23207.1 - 5.8e-14 51.8 0.0 1.5e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pkinase_Tyr PF07714.12 KKK23207.1 - 1.4e-10 40.6 0.0 3.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase GST_N_3 PF13417.1 KKK23207.1 - 0.0044 17.2 0.1 0.014 15.5 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Spc97_Spc98 PF04130.8 KKK23208.1 - 8.6e-88 294.9 0.0 1.1e-87 294.6 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Myosin_tail_1 PF01576.14 KKK23208.1 - 0.11 10.1 0.2 0.17 9.5 0.1 1.1 1 0 0 1 1 1 0 Myosin tail adh_short PF00106.20 KKK23209.1 - 2.1e-28 99.3 5.5 2.8e-28 98.9 3.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK23209.1 - 4e-26 92.2 0.5 4.8e-26 91.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK23209.1 - 2.2e-14 53.4 2.4 3.4e-14 52.9 1.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK23209.1 - 0.00018 21.0 1.0 0.00041 19.8 0.7 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 KKK23210.1 - 1.7e-31 109.2 26.0 1.7e-31 109.2 18.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KKK23210.1 - 0.00097 18.8 4.6 0.23 11.2 0.5 2.8 2 0 0 2 2 2 2 MFS_1 like family DUF1201 PF06716.6 KKK23210.1 - 0.015 15.0 1.1 0.041 13.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) GILT PF03227.11 KKK23212.1 - 7.4e-10 38.6 0.1 1.2e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_2 PF03727.11 KKK23213.1 - 4.6e-27 94.7 0.0 2.7e-21 75.8 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KKK23213.1 - 4e-26 91.6 0.0 8e-25 87.3 0.0 2.6 1 1 0 1 1 1 1 Hexokinase Abhydrolase_3 PF07859.8 KKK23215.1 - 6.3e-20 71.6 0.1 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK23215.1 - 1.6e-11 43.4 0.0 2.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Pyr_redox_3 PF13738.1 KKK23216.1 - 1.1e-26 94.1 0.0 1.6e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK23216.1 - 4.2e-12 45.9 0.0 6.3e-10 38.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KKK23216.1 - 2.4e-09 35.9 0.0 1.3e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.19 KKK23216.1 - 3e-07 29.6 0.1 0.00018 20.5 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KKK23216.1 - 4.4e-06 25.8 0.0 0.00064 18.7 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KKK23216.1 - 6.2e-06 25.4 0.0 0.00043 19.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KKK23216.1 - 1.2e-05 25.5 0.0 0.055 13.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK23216.1 - 6.6e-05 22.8 0.0 0.1 12.4 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK23216.1 - 0.0013 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KKK23216.1 - 0.0013 17.7 0.0 0.012 14.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK23216.1 - 0.0059 15.5 0.0 0.034 12.9 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 KKK23216.1 - 0.0064 16.2 0.1 0.68 9.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KKK23216.1 - 0.022 14.9 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KKK23216.1 - 0.046 13.8 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KKK23216.1 - 0.096 12.1 0.0 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KKK23216.1 - 0.1 11.0 0.0 0.42 9.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KKK23216.1 - 0.22 10.3 0.1 0.45 9.3 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Cupin_8 PF13621.1 KKK23217.1 - 2.3e-39 135.4 0.0 5e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 KKK23217.1 - 5.1e-18 65.2 0.0 8.6e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 KKK23217.1 - 3.5e-15 55.4 16.6 0.00019 21.0 0.5 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK23217.1 - 1.5e-08 34.3 0.1 0.0002 21.2 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 KKK23217.1 - 2.8e-08 33.6 7.3 0.00091 19.3 0.1 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Cupin_4 PF08007.7 KKK23217.1 - 0.00016 21.0 0.0 0.00037 19.8 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_6 PF13964.1 KKK23217.1 - 1.3 9.3 3.9 13 6.1 0.0 4.0 4 0 0 4 4 4 0 Kelch motif DSPc PF00782.15 KKK23218.1 - 4.9e-31 107.0 0.0 5.6e-23 80.9 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KKK23218.1 - 6e-06 25.7 0.0 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KKK23218.1 - 0.016 15.2 0.0 0.079 12.9 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Met_10 PF02475.11 KKK23219.1 - 0.00015 21.4 0.0 0.00048 19.7 0.0 1.9 2 1 0 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KKK23219.1 - 0.0024 17.9 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KKK23219.1 - 0.089 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 EF-hand_6 PF13405.1 KKK23220.1 - 1.2e-08 34.1 0.5 0.0039 16.9 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KKK23220.1 - 0.00087 18.4 0.1 0.0034 16.5 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KKK23220.1 - 0.023 14.0 0.1 0.063 12.6 0.0 1.8 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 KKK23220.1 - 0.062 13.4 5.2 0.13 12.3 0.1 2.8 1 1 1 2 2 2 0 EF-hand domain pair PPR_3 PF13812.1 KKK23221.1 - 0.012 15.8 0.2 0.31 11.4 0.0 3.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain FliD_N PF02465.13 KKK23221.1 - 0.19 12.1 5.6 0.25 11.6 2.8 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TPR_14 PF13428.1 KKK23221.1 - 0.21 12.3 6.8 4.4 8.2 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 KKK23222.1 - 3.6e-06 26.6 1.7 0.0029 17.4 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KKK23222.1 - 0.00077 18.3 0.0 0.0042 15.9 0.0 2.0 2 0 0 2 2 2 1 Coatomer WD associated region CNH PF00780.17 KKK23222.1 - 0.001 18.5 0.0 0.31 10.4 0.0 2.5 2 1 0 2 2 2 2 CNH domain Apc4_WD40 PF12894.2 KKK23222.1 - 0.045 13.2 0.0 9.2 5.8 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.20 KKK23228.1 - 9.6e-20 70.8 0.0 1.2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23228.1 - 1.4e-18 66.9 0.0 2.3e-18 66.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK23228.1 - 0.0083 15.1 0.0 0.041 12.8 0.0 1.8 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KKK23228.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KKK23228.1 - 0.023 13.7 0.1 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ArgJ PF01960.13 KKK23229.1 - 6.8e-144 479.0 0.1 7.8e-144 478.8 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Pkinase PF00069.20 KKK23231.1 - 6.2e-26 91.1 0.0 1.7e-25 89.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23231.1 - 1.1e-09 37.7 0.0 0.00016 20.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KKK23231.1 - 0.00018 21.3 0.1 0.053 13.2 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family LysM PF01476.15 KKK23232.1 - 0.032 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 LysM domain zf-C2H2_6 PF13912.1 KKK23233.1 - 0.0023 17.7 0.6 0.19 11.6 0.1 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KKK23233.1 - 0.033 14.5 0.3 0.094 13.0 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK23233.1 - 0.065 13.5 0.2 0.19 12.1 0.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type APH PF01636.18 KKK23235.1 - 3.4e-13 49.8 0.0 1.3e-12 48.0 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK23235.1 - 0.00025 20.1 0.0 0.0032 16.5 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3435 PF11917.3 KKK23236.1 - 5.5e-17 61.5 0.1 8.2e-17 61.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) TT_ORF2 PF02957.10 KKK23236.1 - 0.078 13.6 0.4 0.18 12.4 0.2 1.6 1 0 0 1 1 1 0 TT viral ORF2 APH PF01636.18 KKK23237.1 - 6e-12 45.7 0.0 2.1e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-FCS PF06467.9 KKK23239.1 - 0.12 12.0 0.4 0.2 11.3 0.3 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif YuzL PF14115.1 KKK23239.1 - 0.29 11.4 1.1 0.7 10.2 0.0 2.1 3 0 0 3 3 3 0 YuzL-like protein Fungal_trans PF04082.13 KKK23240.1 - 0.00031 19.7 0.0 0.00091 18.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain CDC45 PF02724.9 KKK23240.1 - 0.35 8.8 1.6 0.51 8.3 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 KKK23240.1 - 1.2 9.4 9.9 2.3 8.5 6.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KKK23240.1 - 6.8 6.1 12.8 12 5.3 8.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin PC4 PF02229.11 KKK23242.1 - 1.7e-22 78.3 0.2 3.5e-22 77.3 0.0 1.6 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) MIT PF04212.13 KKK23243.1 - 3.1e-09 36.5 1.0 1.5e-08 34.3 0.4 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain PXA PF02194.10 KKK23244.1 - 1e-37 129.5 0.1 2.7e-37 128.1 0.0 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KKK23244.1 - 6.4e-24 84.2 0.1 3.3e-23 81.9 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KKK23244.1 - 4.6e-09 36.0 0.1 6.8e-08 32.3 0.0 2.4 2 0 0 2 2 2 1 PX domain DUF3944 PF13099.1 KKK23244.1 - 0.24 10.9 1.1 0.43 10.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) 4HBT PF03061.17 KKK23245.1 - 7.4e-13 48.4 0.1 1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KKK23245.1 - 0.061 13.3 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) CH PF00307.26 KKK23246.1 - 1.4e-65 218.0 0.0 4e-20 71.8 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KKK23246.1 - 1.9e-08 34.2 1.2 1e-05 25.5 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair CAMSAP_CH PF11971.3 KKK23246.1 - 4.5e-05 23.0 0.0 0.81 9.3 0.0 4.0 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_6 PF13405.1 KKK23246.1 - 0.00089 18.9 4.2 0.05 13.4 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KKK23246.1 - 0.00096 18.2 1.8 0.86 9.0 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 KKK23246.1 - 0.014 14.7 2.8 1.1 8.6 0.2 2.9 2 0 0 2 2 2 0 EF hand DDHD PF02862.12 KKK23247.1 - 3.7e-53 180.6 0.1 3.7e-53 180.6 0.0 2.5 2 1 0 2 2 2 1 DDHD domain PGAP1 PF07819.8 KKK23247.1 - 0.095 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Usp PF00582.21 KKK23247.1 - 0.13 12.4 1.0 0.34 11.0 0.7 1.6 1 0 0 1 1 1 0 Universal stress protein family Lipase_3 PF01764.20 KKK23247.1 - 0.18 11.4 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Mito_carr PF00153.22 KKK23248.1 - 6.4e-72 237.3 0.9 6.5e-23 80.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 KKK23248.1 - 9.4e-25 87.4 0.1 1.8e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 KKK23249.1 - 1.2e-11 44.0 0.0 1.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK23249.1 - 7.5e-08 32.2 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK23249.1 - 3.8e-07 29.8 0.0 5.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK23249.1 - 0.0027 17.4 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Peptidase_M24 PF00557.19 KKK23250.1 - 8.3e-56 188.8 0.0 1.1e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KKK23250.1 - 1.9e-24 85.5 0.0 7e-24 83.7 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain BTB PF00651.26 KKK23251.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Peptidase_M1 PF01433.15 KKK23252.1 - 6.3e-74 249.4 0.0 8.4e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KKK23252.1 - 6.6e-44 148.9 0.0 1.2e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KKK23252.1 - 9.7e-17 61.2 0.1 1.7e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KKK23252.1 - 0.072 13.0 1.8 0.3 11.0 1.2 2.0 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Big_4 PF07532.6 KKK23252.1 - 0.073 12.5 1.0 0.81 9.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) Ubiq_cyt_C_chap PF03981.7 KKK23253.1 - 4.9e-31 107.4 0.1 6e-31 107.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Aldedh PF00171.17 KKK23254.1 - 4.4e-15 54.9 7.2 7.9e-10 37.6 4.3 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Erf4 PF10256.4 KKK23254.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Tbf5 PF06331.7 KKK23254.1 - 0.23 11.2 1.2 1.1 9.0 0.0 2.5 2 1 1 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 PCI PF01399.22 KKK23255.1 - 0.00091 19.5 0.0 0.014 15.6 0.0 2.8 3 0 0 3 3 3 1 PCI domain TPR_1 PF00515.23 KKK23255.1 - 0.033 13.8 0.2 0.07 12.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK23255.1 - 0.036 13.9 0.1 0.096 12.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK23255.1 - 0.052 13.3 0.2 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat GST_C_2 PF13410.1 KKK23257.1 - 4.3e-18 64.9 0.0 6.6e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK23257.1 - 4.9e-06 26.9 0.0 7.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KKK23257.1 - 6e-06 26.1 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 KKK23258.1 - 1.8e-67 223.1 3.4 3.6e-22 77.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KKK23258.1 - 3.7e-22 78.2 2.2 3.5e-13 49.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KKK23258.1 - 2e-20 70.4 5.4 1.8e-06 26.8 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 KKK23258.1 - 3.3e-18 64.1 3.6 5e-06 25.6 0.1 3.7 3 1 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KKK23258.1 - 7.2e-14 50.3 6.7 0.00077 19.1 0.0 4.0 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KKK23258.1 - 2.1e-12 46.4 0.7 7.8e-07 28.6 0.0 2.7 1 1 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KKK23258.1 - 3.5e-07 30.2 0.1 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KKK23258.1 - 0.0096 15.5 0.9 7.1 6.3 0.0 3.4 4 0 0 4 4 4 2 EF hand Cyclin_N PF00134.18 KKK23259.1 - 3.3e-11 42.8 0.0 6.4e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4452 PF14618.1 KKK23260.1 - 9e-74 246.7 6.7 1.1e-73 246.4 4.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) SNARE PF05739.14 KKK23262.1 - 3e-14 52.4 3.2 3e-14 52.4 2.2 2.2 2 0 0 2 2 2 1 SNARE domain MDMPI_N PF11716.3 KKK23262.1 - 0.012 16.0 0.1 0.034 14.5 0.1 1.7 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Phage_GP20 PF06810.6 KKK23262.1 - 0.023 14.1 2.3 2.1 7.7 0.1 2.7 3 0 0 3 3 3 0 Phage minor structural protein GP20 TPR_19 PF14559.1 KKK23262.1 - 0.05 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat FliJ PF02050.11 KKK23262.1 - 0.064 13.3 3.6 0.74 9.8 0.3 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 KKK23262.1 - 0.097 12.4 0.3 0.097 12.4 0.2 1.9 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Use1 PF09753.4 KKK23262.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 Syntaxin PF00804.20 KKK23262.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.4 2 1 0 2 2 2 0 Syntaxin WXG100 PF06013.7 KKK23262.1 - 0.28 11.1 2.3 5.2 7.1 0.1 3.2 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Tropomyosin PF00261.15 KKK23262.1 - 1.9 7.5 7.2 16 4.4 0.0 3.3 3 1 1 4 4 4 0 Tropomyosin PilJ PF13675.1 KKK23262.1 - 4.2 7.7 7.1 0.71 10.2 0.1 2.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term zf-TRAF PF02176.13 KKK23263.1 - 1.3e-11 44.7 32.4 2.5e-10 40.5 2.5 4.3 2 2 2 4 4 4 2 TRAF-type zinc finger zf-RING_2 PF13639.1 KKK23263.1 - 1.8e-07 30.8 13.0 1.8e-07 30.8 9.0 3.5 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK23263.1 - 3.2e-07 29.8 11.9 3.2e-07 29.8 8.2 3.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK23263.1 - 3.3e-06 26.7 11.5 3.3e-06 26.7 8.0 3.9 4 1 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KKK23263.1 - 6.8e-06 25.8 12.3 6.8e-06 25.8 8.6 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KKK23263.1 - 1.5e-05 24.5 10.5 1.5e-05 24.5 7.2 3.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 KKK23263.1 - 1.6e-05 24.6 16.4 0.002 17.7 3.8 3.2 2 1 1 3 3 3 2 Seven in absentia protein family zf-RING_UBOX PF13445.1 KKK23263.1 - 1.7e-05 24.4 8.2 1.7e-05 24.4 5.7 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KKK23263.1 - 3.8e-05 23.6 13.3 3.8e-05 23.6 9.2 3.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prominin PF05478.6 KKK23263.1 - 0.016 12.7 1.2 0.022 12.3 0.8 1.1 1 0 0 1 1 1 0 Prominin PilN PF05137.8 KKK23263.1 - 0.035 13.9 0.1 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) AhpC-TSA_2 PF13911.1 KKK23283.1 - 7.7e-19 67.7 0.0 9.5e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KKK23283.1 - 0.0039 16.8 0.0 0.0079 15.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KKK23283.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.4 1 1 0 1 1 1 0 Redoxin DUF4237 PF14021.1 KKK23284.1 - 1.2e-31 108.8 0.0 1.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) Bgal_small_N PF02929.12 KKK23284.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Beta galactosidase small chain Gln-synt_C PF00120.19 KKK23294.1 - 4.2e-62 209.6 0.0 5.3e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Herpes_alk_exo PF01771.12 KKK23294.1 - 0.23 9.8 0.0 0.36 9.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus alkaline exonuclease Malate_synthase PF01274.17 KKK23295.1 - 1.3e-236 785.6 0.0 1.5e-236 785.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Shikimate_dh_N PF08501.6 KKK23296.1 - 3.3e-24 84.7 0.0 5.4e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KKK23296.1 - 5.5e-16 58.8 0.0 9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase PLA2_B PF01735.13 KKK23303.1 - 6.8e-195 647.9 1.0 8.1e-195 647.6 0.7 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MMPL PF03176.10 KKK23307.1 - 0.089 11.4 1.1 0.2 10.3 0.7 1.5 1 0 0 1 1 1 0 MMPL family GST_N_3 PF13417.1 KKK23308.1 - 3.1e-24 85.0 0.1 5.8e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK23308.1 - 1.8e-16 59.8 0.0 3.9e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK23308.1 - 2.2e-06 27.4 1.4 3.8e-06 26.6 0.4 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK23308.1 - 1.2e-05 25.3 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KKK23308.1 - 0.023 14.6 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Cas_Cas02710 PF09670.5 KKK23308.1 - 0.024 13.2 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) GST_C_3 PF14497.1 KKK23308.1 - 0.075 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SUZ-C PF12901.2 KKK23309.1 - 0.0039 16.7 6.1 0.012 15.2 4.3 2.0 1 0 0 1 1 1 1 SUZ-C motif Pyridox_ox_2 PF12900.2 KKK23312.1 - 0.014 15.1 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase TMEM154 PF15102.1 KKK23312.1 - 0.3 10.8 3.8 0.37 10.4 2.6 1.1 1 0 0 1 1 1 0 TMEM154 protein family E1-E2_ATPase PF00122.15 KKK23314.1 - 5.3e-14 51.8 0.3 2.3e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 KKK23314.1 - 9.9e-09 34.5 4.6 6.7e-06 25.4 3.2 2.4 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus DctM PF06808.7 KKK23314.1 - 3e-05 22.7 0.3 3.5e-05 22.5 0.2 1.0 1 0 0 1 1 1 1 DctM-like transporters Glyco_hydro_28 PF00295.12 KKK23315.1 - 4e-51 173.9 7.2 5.2e-51 173.5 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KKK23315.1 - 0.0013 18.4 7.9 0.012 15.4 5.4 2.3 1 1 0 1 1 1 1 Right handed beta helix region MmgE_PrpD PF03972.9 KKK23316.1 - 2.7e-150 500.4 0.0 3.1e-150 500.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Ubiquitin_2 PF14560.1 KKK23316.1 - 0.03 14.5 0.3 0.072 13.3 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain DUF4319 PF14203.1 KKK23316.1 - 0.12 11.9 0.1 0.3 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) DNA_methylase PF00145.12 KKK23317.1 - 6.3e-44 150.4 0.0 1.1e-31 110.2 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_2 PF00310.16 KKK23318.1 - 4.4e-21 75.0 0.0 2.3e-15 56.1 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KKK23318.1 - 1.3e-15 57.4 0.0 2.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KKK23318.1 - 7.3e-14 51.5 0.0 3.2e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KKK23318.1 - 6.3e-12 45.3 0.0 1.7e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KKK23318.1 - 2.6e-06 26.3 0.0 4.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.1 KKK23318.1 - 0.071 12.4 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl transferase Ribosomal_S17 PF00366.15 KKK23319.1 - 9e-31 105.7 1.2 1.3e-30 105.2 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 KKK23320.1 - 0 1206.9 61.1 0 1206.5 42.3 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KKK23320.1 - 7.9e-128 425.6 5.2 1.6e-127 424.7 3.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Sec8_exocyst PF04048.9 KKK23320.1 - 0.0044 16.6 3.2 0.011 15.4 2.2 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Gp_dh_C PF02800.15 KKK23320.1 - 0.052 12.9 0.1 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Pro-NT_NN PF07421.6 KKK23320.1 - 0.12 11.8 0.2 2.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor TMPIT PF07851.8 KKK23320.1 - 2.2 7.2 3.3 4.1 6.3 2.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein ANTH PF07651.11 KKK23321.1 - 1.3e-61 207.7 0.6 1.7e-61 207.4 0.4 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KKK23321.1 - 7.9e-06 25.7 0.1 5e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 ENTH domain DAGK_cat PF00781.19 KKK23324.1 - 5.4e-10 38.8 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Mac PF12464.3 KKK23325.1 - 3e-13 49.5 0.0 7.8e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 KKK23325.1 - 9.4e-10 38.2 8.4 1.8e-09 37.3 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.19 KKK23325.1 - 1.6e-09 36.8 4.7 0.00011 21.4 0.1 3.7 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK23325.1 - 2.6e-09 36.4 1.8 2.5e-06 26.9 0.0 3.8 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase ALAD PF00490.16 KKK23326.1 - 1.7e-100 336.0 0.0 8.5e-99 330.5 0.0 2.0 1 1 1 2 2 2 2 Delta-aminolevulinic acid dehydratase DUF793 PF05633.6 KKK23326.1 - 0.27 9.9 1.1 0.41 9.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) NUDIX PF00293.23 KKK23327.1 - 2.6e-18 65.9 0.0 4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 KKK23328.1 - 0.00014 21.5 0.0 0.00031 20.3 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain zf-C3HC4_3 PF13920.1 KKK23329.1 - 1.4e-12 47.0 6.0 2.5e-12 46.2 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) EST1_DNA_bind PF10373.4 KKK23329.1 - 1.5e-11 44.0 0.0 3.8e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain zf-C3HC4_2 PF13923.1 KKK23329.1 - 1e-07 31.8 8.2 2.1e-07 30.8 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK23329.1 - 4.4e-06 26.2 6.9 8.5e-06 25.3 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK23329.1 - 6.1e-06 25.9 7.1 1.2e-05 25.0 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KKK23329.1 - 0.00031 20.4 6.0 0.00059 19.5 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KKK23329.1 - 0.22 11.1 5.6 0.42 10.2 3.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KKK23329.1 - 0.28 11.0 7.3 0.58 10.0 5.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KKK23329.1 - 1.8 8.3 8.2 0.3 10.8 2.0 2.3 1 1 1 2 2 2 0 RING-type zinc-finger Glycos_transf_2 PF00535.21 KKK23330.1 - 4.7e-21 75.2 0.0 6.2e-11 42.2 0.0 2.4 1 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KKK23330.1 - 6.1e-06 26.1 0.1 0.024 14.4 0.1 3.2 2 2 1 3 3 3 2 Glycosyltransferase like family 2 LrgB PF04172.11 KKK23330.1 - 0.049 12.7 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 LrgB-like family Autophagy_N PF03986.8 KKK23333.1 - 7.9e-51 171.6 0.8 9.7e-51 171.3 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KKK23333.1 - 1e-21 76.8 0.2 2.3e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KKK23333.1 - 9.4e-15 53.4 0.3 1.5e-14 52.7 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF1471 PF07338.8 KKK23333.1 - 0.036 13.7 0.4 0.09 12.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Cyclin_N PF00134.18 KKK23334.1 - 0.0035 16.8 0.0 0.073 12.6 0.0 2.6 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 KKK23334.1 - 0.0068 16.1 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Spore_coat_CotO PF14153.1 KKK23335.1 - 0.11 11.9 2.7 0.17 11.2 1.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO HAUS5 PF14817.1 KKK23335.1 - 0.39 9.2 8.5 0.55 8.7 5.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 IncA PF04156.9 KKK23335.1 - 0.41 10.2 4.5 0.74 9.3 3.1 1.4 1 0 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 KKK23335.1 - 6.6 6.4 15.5 0.16 11.6 1.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding EMP24_GP25L PF01105.19 KKK23365.1 - 8.6e-48 162.4 0.6 1e-47 162.2 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CENP-F_leu_zip PF10473.4 KKK23375.1 - 0.0069 16.2 6.6 0.0069 16.2 4.6 3.1 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 KKK23375.1 - 0.63 9.2 16.0 1.4 8.0 3.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.3 KKK23375.1 - 1.2 9.0 21.8 0.76 9.6 4.6 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2570 PF10828.3 KKK23375.1 - 2.6 7.6 11.7 1.2 8.7 5.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Sel1 PF08238.7 KKK23380.1 - 1.7e-40 136.5 40.1 2.2e-05 24.9 0.2 12.5 12 0 0 12 12 12 9 Sel1 repeat TPR_16 PF13432.1 KKK23380.1 - 0.00042 20.8 13.4 0.67 10.6 0.3 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK23380.1 - 0.0027 18.1 0.2 4.2 8.2 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK23380.1 - 0.48 10.3 9.9 26 4.8 0.0 5.9 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KKK23380.1 - 8.9 6.1 0.0 8.9 6.1 0.0 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat Lectin_N PF03954.9 KKK23381.1 - 0.0077 15.6 0.4 0.11 11.8 0.2 2.1 1 1 0 1 1 1 1 Hepatic lectin, N-terminal domain DUF1192 PF06698.6 KKK23381.1 - 0.01 15.6 6.4 0.76 9.6 0.3 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) FlxA PF14282.1 KKK23381.1 - 0.015 15.2 3.0 4 7.4 1.6 2.3 2 0 0 2 2 2 0 FlxA-like protein Mut7-C PF01927.11 KKK23381.1 - 0.043 13.7 0.6 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 Mut7-C RNAse domain FliD_C PF07195.7 KKK23381.1 - 0.21 10.8 1.7 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Mnd1 PF03962.10 KKK23381.1 - 0.35 10.5 3.7 0.38 10.3 0.8 1.9 1 1 1 2 2 2 0 Mnd1 family Mei5 PF10376.4 KKK23381.1 - 0.9 9.0 9.5 1.9 7.9 6.6 1.7 1 1 0 1 1 1 0 Double-strand recombination repair protein TBPIP PF07106.8 KKK23381.1 - 1.4 8.4 4.2 0.99 8.9 0.9 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Snapin_Pallidin PF14712.1 KKK23381.1 - 1.6 9.0 6.6 0.59 10.4 2.6 1.8 2 1 0 2 2 2 0 Snapin/Pallidin CENP-F_leu_zip PF10473.4 KKK23381.1 - 1.7 8.5 8.2 0.44 10.3 2.2 2.1 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.1 KKK23381.1 - 2.4 8.6 6.4 0.76 10.2 0.9 2.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Cortex-I_coil PF09304.5 KKK23381.1 - 2.7 8.0 9.0 7.1 6.7 2.0 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil WD40 PF00400.27 KKK23382.1 - 2.2e-09 36.8 8.0 0.0061 16.4 0.2 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 KKK23382.1 - 0.00096 18.9 0.0 1.2 8.7 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RNA_pol_Rpb1_1 PF04997.7 KKK23383.1 - 2.7e-121 404.9 0.0 4.2e-121 404.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KKK23383.1 - 4.7e-85 285.1 0.0 3e-84 282.5 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KKK23383.1 - 1.6e-71 239.6 0.0 3.8e-71 238.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KKK23383.1 - 7.6e-63 211.6 1.2 1.6e-62 210.6 0.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KKK23383.1 - 3.1e-46 157.0 0.0 8.4e-46 155.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KKK23383.1 - 2.3e-42 143.9 7.5 2.3e-42 143.9 5.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KKK23383.1 - 3.3e-37 126.5 0.1 7.8e-37 125.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KKK23383.1 - 2.9e-11 42.5 204.0 0.068 13.3 8.9 14.3 9 3 5 15 15 15 12 RNA polymerase Rpb1 C-terminal repeat Kelch_5 PF13854.1 KKK23384.1 - 2.2e-23 81.7 0.3 8.4e-06 25.6 0.1 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 KKK23384.1 - 3.7e-23 81.0 3.1 4.7e-09 35.8 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KKK23384.1 - 1.6e-21 75.8 3.2 5e-09 36.0 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KKK23384.1 - 9e-21 73.1 2.7 5.6e-06 26.2 0.0 5.0 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 KKK23384.1 - 1.6e-17 62.7 0.5 0.0015 18.0 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 KKK23384.1 - 3.7e-17 61.3 0.2 4.2e-05 23.1 0.0 4.4 4 0 0 4 4 4 3 Kelch motif BTB PF00651.26 KKK23384.1 - 4.3e-09 36.3 0.0 8.6e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 KKK23384.1 - 0.085 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch WD40 PF00400.27 KKK23385.1 - 9.5e-25 85.5 16.6 1.4e-07 31.1 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KKK23385.1 - 3.6e-05 23.5 0.3 0.0026 17.4 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Amidase PF01425.16 KKK23386.1 - 2.2e-08 33.4 0.0 1.4e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Amidase Glyco_hydro_1 PF00232.13 KKK23387.1 - 1.3e-147 491.6 0.0 1.6e-147 491.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_43 PF04616.9 KKK23390.1 - 2.5e-27 95.6 2.5 9.8e-27 93.7 1.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Apc1 PF12859.2 KKK23392.1 - 1e-32 112.4 0.7 4.3e-32 110.4 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KKK23392.1 - 0.00085 19.4 8.1 0.46 10.8 0.0 4.7 5 0 0 5 5 5 3 Proteasome/cyclosome repeat Glyco_transf_8 PF01501.15 KKK23393.1 - 5.2e-14 52.1 0.0 5.5e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_hydro_18 PF00704.23 KKK23394.1 - 4.2e-37 128.3 0.0 5e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KKK23394.1 - 5.5e-08 32.6 8.4 5.5e-08 32.6 5.8 3.0 2 1 0 2 2 2 2 Chitin recognition protein RPAP1_C PF08620.5 KKK23395.1 - 7.6e-29 99.3 0.0 1.3e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KKK23395.1 - 7.2e-17 60.7 6.8 1.5e-16 59.6 4.7 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal HUN PF08729.5 KKK23396.1 - 5.1e-14 51.8 0.3 5.1e-14 51.8 0.2 2.0 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Pyr_redox_3 PF13738.1 KKK23397.1 - 6.2e-19 68.8 0.0 9.9e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK23397.1 - 8.3e-12 44.6 0.0 3.1e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KKK23397.1 - 3.5e-09 35.4 0.0 4.6e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KKK23397.1 - 5.4e-09 36.2 0.0 6.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK23397.1 - 0.00023 21.1 0.0 0.00088 19.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK23397.1 - 0.0074 16.0 0.1 0.046 13.5 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KKK23397.1 - 0.027 13.5 0.1 0.071 12.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Dam PF05869.6 KKK23397.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) PMP1_2 PF08114.6 KKK23399.1 - 1.2 8.6 7.7 0.89 9.0 0.7 2.8 2 0 0 2 2 2 0 ATPase proteolipid family MFS_1 PF07690.11 KKK23400.1 - 1.2e-29 103.1 39.4 1.2e-29 103.1 27.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_S10 PF00450.17 KKK23401.1 - 3.4e-110 369.0 0.5 4.2e-110 368.7 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase UNC-93 PF05978.11 KKK23402.1 - 7e-11 41.8 6.6 7e-11 41.8 4.6 3.4 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KKK23402.1 - 1e-10 40.9 36.0 1e-10 40.9 25.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.15 KKK23403.1 - 1.4e-13 51.2 0.0 2.6e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KKK23403.1 - 6.2e-11 42.8 4.1 6.6e-10 39.4 2.8 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KKK23403.1 - 1.3e-05 24.9 0.0 6.4e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KKK23403.1 - 7.3e-05 22.1 0.3 0.00014 21.1 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family Pam17 PF08566.5 KKK23405.1 - 3.3e-58 196.2 3.1 9.2e-54 181.7 0.0 2.6 2 1 1 3 3 3 2 Mitochondrial import protein Pam17 Med3 PF11593.3 KKK23405.1 - 0.29 10.3 10.0 0.47 9.6 6.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Far-17a_AIG1 PF04750.9 KKK23406.1 - 4.5e-62 208.7 10.2 5e-62 208.6 7.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DIM PF08194.7 KKK23406.1 - 6.2 6.8 6.7 20 5.2 0.3 3.2 3 0 0 3 3 3 0 DIM protein Ank_2 PF12796.2 KKK23411.1 - 2.6e-33 114.1 5.7 3e-16 59.5 0.0 5.0 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK23411.1 - 1.3e-24 86.0 11.8 5.1e-09 36.4 0.0 6.2 2 1 4 7 7 7 5 Ankyrin repeats (many copies) SPX PF03105.14 KKK23411.1 - 1.6e-23 83.9 6.9 1.9e-16 60.6 1.6 2.4 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 KKK23411.1 - 5.4e-23 79.6 14.6 0.0001 21.8 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 KKK23411.1 - 3.6e-19 68.3 8.2 0.00019 21.5 0.0 6.5 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK23411.1 - 1.2e-17 62.2 12.2 0.0009 19.2 0.0 8.2 9 0 0 9 9 9 4 Ankyrin repeat GDPD PF03009.12 KKK23411.1 - 1.1e-08 34.9 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family APH PF01636.18 KKK23418.1 - 1e-15 58.1 0.1 8.2e-15 55.1 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KKK23418.1 - 0.0055 15.7 0.0 0.0091 15.0 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase DUF155 PF02582.9 KKK23419.1 - 5.8e-53 179.3 0.2 9.4e-53 178.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 KKK23419.1 - 0.034 14.3 0.1 0.34 11.1 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 U3_snoRNA_assoc PF08297.6 KKK23420.1 - 5.4e-22 77.8 1.0 5.4e-22 77.8 0.7 3.2 3 0 0 3 3 3 2 U3 snoRNA associated RRP14 PF15459.1 KKK23420.1 - 0.041 13.9 2.7 0.041 13.9 1.9 2.6 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Asp-B-Hydro_N PF05279.6 KKK23420.1 - 0.93 9.2 15.1 1.4 8.6 10.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CBFB_NFYA PF02045.10 KKK23420.1 - 1.4 9.5 6.4 3.6 8.2 4.5 1.7 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B PRCC PF10253.4 KKK23421.1 - 1.3e-42 146.5 5.1 1.3e-42 146.5 3.6 3.2 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Cwf_Cwc_15 PF04889.7 KKK23421.1 - 0.043 13.5 1.7 0.098 12.3 1.2 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ARS2 PF04959.8 KKK23421.1 - 0.077 13.1 0.2 0.077 13.1 0.1 2.1 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Nucleic_acid_bd PF13820.1 KKK23421.1 - 0.079 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative nucleic acid-binding region Adeno_E3_14_5 PF04834.7 KKK23421.1 - 0.32 11.4 1.1 0.73 10.2 0.8 1.6 1 0 0 1 1 1 0 Early E3 14.5 kDa protein Mito_fiss_reg PF05308.6 KKK23421.1 - 3.1 7.1 15.4 0.032 13.6 4.9 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Pol_alpha_B_N PF08418.5 KKK23421.1 - 7.5 6.0 15.3 3.4 7.1 1.3 2.6 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal CTK3 PF12243.3 KKK23422.1 - 1.2e-59 199.9 0.1 1.5e-59 199.5 0.1 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KKK23422.1 - 1.8e-20 72.6 5.0 1.8e-20 72.6 3.4 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 KKK23422.1 - 0.065 12.9 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial glycoprotein adh_short PF00106.20 KKK23423.1 - 9.6e-23 80.9 0.2 1.4e-22 80.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK23423.1 - 3.8e-19 69.4 0.2 4.8e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KKK23423.1 - 3.8e-07 30.2 0.0 7.1e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KKK23423.1 - 8.3e-06 25.5 0.3 1.5e-05 24.7 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK23423.1 - 4.8e-05 22.9 0.0 7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PAE PF03283.8 KKK23423.1 - 0.017 13.7 0.1 0.023 13.3 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase DUF1776 PF08643.5 KKK23423.1 - 0.034 13.2 0.0 6.1 5.8 0.0 2.6 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.14 KKK23423.1 - 0.041 12.5 0.0 0.066 11.9 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KKK23423.1 - 0.043 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 KKK23423.1 - 0.051 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 KKK23423.1 - 0.093 12.2 0.1 0.35 10.4 0.0 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase AAA_5 PF07728.9 KKK23424.1 - 3.7e-122 402.5 0.7 4.5e-22 78.2 0.0 9.0 7 1 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK23424.1 - 7.4e-27 93.5 0.0 1e-10 41.3 0.0 6.6 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KKK23424.1 - 2.8e-21 76.1 0.0 3.8e-05 23.8 0.0 6.3 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK23424.1 - 5.7e-19 68.4 0.0 0.004 17.0 0.0 8.0 8 1 0 8 8 6 3 AAA domain AAA_14 PF13173.1 KKK23424.1 - 5.1e-17 61.9 0.0 0.00025 20.9 0.0 6.7 7 0 0 7 7 5 2 AAA domain AAA_16 PF13191.1 KKK23424.1 - 2.1e-16 60.4 15.0 0.0009 19.2 0.2 7.8 8 0 0 8 8 5 3 AAA ATPase domain AAA_22 PF13401.1 KKK23424.1 - 6e-15 55.5 1.9 0.037 14.1 0.0 7.9 8 0 0 8 8 7 3 AAA domain Sigma54_activat PF00158.21 KKK23424.1 - 2.2e-14 53.2 0.0 0.0085 15.5 0.1 5.6 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_17 PF13207.1 KKK23424.1 - 3.4e-14 53.6 0.0 0.0024 18.6 0.0 6.4 5 0 0 5 5 5 2 AAA domain Sigma54_activ_2 PF14532.1 KKK23424.1 - 1.5e-13 50.9 0.3 0.0024 17.9 0.1 6.2 6 0 0 6 6 5 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 KKK23424.1 - 7.6e-13 48.0 0.3 0.077 12.0 0.0 6.3 5 0 0 5 5 5 3 Zeta toxin AAA_18 PF13238.1 KKK23424.1 - 7.2e-12 45.7 0.4 0.014 15.6 0.1 6.4 5 0 0 5 5 5 2 AAA domain UPF0079 PF02367.12 KKK23424.1 - 2.1e-11 43.5 3.0 0.027 14.0 0.0 5.5 5 0 0 5 5 5 3 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KKK23424.1 - 6.4e-11 42.7 1.9 0.038 14.2 0.0 6.0 6 0 0 6 6 6 2 ABC transporter Mg_chelatase PF01078.16 KKK23424.1 - 8.1e-11 41.4 1.1 3.1 6.9 0.1 8.2 8 1 1 9 9 9 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 KKK23424.1 - 1.8e-10 40.1 2.0 0.58 9.0 0.0 5.4 5 0 0 5 5 5 2 Type II/IV secretion system protein Arch_ATPase PF01637.13 KKK23424.1 - 3.2e-09 36.8 0.1 1.6 8.3 0.0 5.7 5 0 0 5 5 5 2 Archaeal ATPase RuvB_N PF05496.7 KKK23424.1 - 4.4e-09 35.7 1.6 0.099 11.6 0.0 5.7 6 0 0 6 6 6 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK23424.1 - 4.4e-09 35.9 3.5 0.047 13.4 0.1 5.5 5 0 0 5 5 5 2 Part of AAA domain RNA_helicase PF00910.17 KKK23424.1 - 5.3e-09 36.2 0.5 1 9.5 0.0 5.7 5 0 0 5 5 5 2 RNA helicase NACHT PF05729.7 KKK23424.1 - 1.1e-08 34.9 1.8 0.12 12.0 0.1 4.3 3 0 0 3 3 3 2 NACHT domain AAA_29 PF13555.1 KKK23424.1 - 1.9e-08 33.7 2.6 0.38 10.3 0.0 5.7 5 0 0 5 5 5 2 P-loop containing region of AAA domain Miro PF08477.8 KKK23424.1 - 2.3e-08 34.5 2.5 0.31 11.5 0.1 5.8 5 0 0 5 5 5 1 Miro-like protein AAA_25 PF13481.1 KKK23424.1 - 2.7e-08 33.4 1.2 0.24 10.7 0.0 5.3 5 0 0 5 5 4 2 AAA domain DUF815 PF05673.8 KKK23424.1 - 4.4e-08 32.3 0.9 0.24 10.3 0.1 4.8 5 0 0 5 5 5 3 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 KKK23424.1 - 1.2e-07 31.6 0.1 0.067 13.1 0.0 5.5 5 0 0 5 5 5 1 50S ribosome-binding GTPase MobB PF03205.9 KKK23424.1 - 1.5e-07 31.1 1.7 0.49 10.1 0.1 5.5 5 0 0 5 5 5 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KKK23424.1 - 4.7e-07 29.3 2.7 0.064 12.7 0.0 5.2 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 KKK23424.1 - 1.6e-06 27.9 0.0 0.41 10.2 0.0 3.7 3 0 0 3 3 3 2 Bacterial dnaA protein DUF258 PF03193.11 KKK23424.1 - 2.7e-06 26.6 2.5 0.19 10.9 0.1 5.1 5 0 0 5 5 5 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 KKK23424.1 - 3.6e-06 27.0 1.0 1.6 8.6 0.1 5.4 5 0 0 5 5 5 1 AAA domain SRP54 PF00448.17 KKK23424.1 - 1.3e-05 24.6 4.9 0.12 11.7 0.1 4.9 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 KKK23424.1 - 4.1e-05 23.3 4.4 0.35 10.5 0.1 4.4 4 0 0 4 4 4 2 NTPase IstB_IS21 PF01695.12 KKK23424.1 - 4.2e-05 23.0 0.0 2.6 7.4 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein SRPRB PF09439.5 KKK23424.1 - 0.00014 21.1 1.1 3.7 6.7 0.0 4.7 5 0 0 5 5 4 0 Signal recognition particle receptor beta subunit MCM PF00493.18 KKK23424.1 - 0.00019 20.3 0.4 5.9 5.5 0.0 4.4 5 0 0 5 5 4 0 MCM2/3/5 family ATP_bind_1 PF03029.12 KKK23424.1 - 0.00034 20.2 1.7 2.4 7.6 0.0 4.6 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein TIP49 PF06068.8 KKK23424.1 - 0.00057 18.7 4.6 0.11 11.1 0.0 5.0 6 0 0 6 6 6 1 TIP49 C-terminus CPT PF07931.7 KKK23424.1 - 0.00063 19.4 0.3 2.9 7.4 0.0 4.9 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.2 KKK23424.1 - 0.0027 16.8 0.5 2 7.4 0.0 3.8 4 0 0 4 4 4 1 P-loop containing dynein motor region D3 NB-ARC PF00931.17 KKK23424.1 - 0.0029 16.5 1.0 14 4.3 0.1 3.7 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.14 KKK23424.1 - 0.004 16.6 2.6 6.1 6.2 0.1 4.9 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 KKK23424.1 - 0.004 16.4 1.9 2.4 7.4 0.0 4.5 5 0 0 5 5 4 1 Ferrous iron transport protein B AAA_24 PF13479.1 KKK23424.1 - 0.0054 16.3 0.1 23 4.4 0.0 4.5 5 0 0 5 5 4 0 AAA domain ResIII PF04851.10 KKK23424.1 - 0.011 15.5 9.7 0.42 10.4 0.0 4.3 5 0 0 5 5 3 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KKK23424.1 - 0.012 14.6 0.2 29 3.6 0.0 4.1 4 0 0 4 4 4 0 KaiC AAA_6 PF12774.2 KKK23424.1 - 0.035 13.6 0.0 15 5.0 0.0 3.8 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region D1 KTI12 PF08433.5 KKK23424.1 - 0.039 13.1 0.7 19 4.3 0.0 4.3 5 0 0 5 5 3 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 KKK23424.1 - 0.096 12.1 0.0 18 4.7 0.0 3.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 KKK23424.1 - 0.11 11.9 0.0 21 4.4 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 KKK23424.1 - 0.12 11.1 6.4 0.49 9.1 0.2 3.3 4 0 0 4 4 4 0 ArgK protein CbiA PF01656.18 KKK23424.1 - 0.25 10.7 1.9 4 6.8 0.1 3.0 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Voltage_CLC PF00654.15 KKK23425.1 - 5.6e-76 255.8 22.6 5.6e-76 255.8 15.7 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KKK23425.1 - 4.4e-07 29.5 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain XLF PF09302.6 KKK23426.1 - 1.6e-34 119.1 0.9 1.6e-34 119.1 0.7 1.5 2 0 0 2 2 2 1 XLF (XRCC4-like factor) 4HBT PF03061.17 KKK23436.1 - 4e-14 52.5 0.1 5.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KKK23436.1 - 0.023 14.4 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.1 KKK23436.1 - 0.031 14.2 0.0 0.045 13.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) DUF3574 PF12098.3 KKK23436.1 - 0.054 13.0 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) PI-PLC-X PF00388.14 KKK23436.1 - 0.15 11.4 0.0 0.21 11.0 0.0 1.3 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Tfb2 PF03849.9 KKK23437.1 - 4.2e-143 476.4 0.0 8.1e-143 475.4 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KKK23437.1 - 1.2e-05 25.0 0.0 4e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 KKK23437.1 - 0.018 14.4 0.0 0.053 12.9 0.0 1.8 1 0 0 1 1 1 0 Anti-repressor SinI Zip PF02535.17 KKK23438.1 - 1.4 7.8 3.3 2.3 7.1 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.11 KKK23438.1 - 1.7 7.8 5.0 2.7 7.2 3.5 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein PhzC-PhzF PF02567.11 KKK23439.1 - 1.1e-16 60.9 0.2 1.4e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein TIMELESS PF04821.9 KKK23440.1 - 1.2e-96 323.0 0.0 2.7e-96 321.8 0.0 1.6 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 KKK23440.1 - 1.4e-87 294.9 35.4 4.9e-65 220.5 0.0 4.2 2 1 2 4 4 4 4 Timeless protein C terminal region 3HCDH_N PF02737.13 KKK23441.1 - 4.6e-52 176.2 1.2 6.5e-52 175.8 0.9 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KKK23441.1 - 3.9e-34 116.9 0.0 9.4e-34 115.7 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KKK23441.1 - 0.0002 21.2 0.2 0.00046 20.0 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KKK23441.1 - 0.0011 18.3 0.3 0.0034 16.8 0.1 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KKK23441.1 - 0.0016 18.1 0.2 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 KKK23441.1 - 0.0092 14.9 0.4 0.018 13.9 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KKK23441.1 - 0.051 13.6 0.3 0.11 12.6 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KKK23441.1 - 0.079 12.9 0.6 0.24 11.4 0.1 2.0 2 1 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KKK23441.1 - 0.092 11.8 0.2 0.2 10.8 0.1 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK23441.1 - 0.094 13.1 1.4 0.29 11.6 0.4 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Actin PF00022.14 KKK23442.1 - 5.6e-114 380.6 0.0 6.5e-114 380.4 0.0 1.0 1 0 0 1 1 1 1 Actin AAA_12 PF13087.1 KKK23443.1 - 3.8e-27 94.9 0.0 6.8e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK23443.1 - 9.3e-24 84.2 0.0 2.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK23443.1 - 4.5e-10 39.1 0.1 4.9e-09 35.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KKK23443.1 - 1.1e-05 25.1 0.0 0.0018 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KKK23443.1 - 1.9e-05 24.5 0.0 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KKK23443.1 - 0.00025 20.6 0.1 0.093 12.2 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KKK23443.1 - 0.0018 17.7 0.0 0.0044 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KKK23443.1 - 0.0025 17.9 0.0 0.012 15.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK23443.1 - 0.0032 17.6 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 KKK23443.1 - 0.0036 16.2 0.1 0.27 10.1 0.0 2.8 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain DEAD PF00270.24 KKK23443.1 - 0.0058 16.1 0.1 0.042 13.3 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_16 PF13191.1 KKK23443.1 - 0.0079 16.1 0.0 0.027 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 KKK23443.1 - 0.012 14.5 0.6 0.021 13.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KKK23443.1 - 0.026 13.6 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin UvrD-helicase PF00580.16 KKK23443.1 - 0.028 13.7 0.0 0.088 12.0 0.0 1.8 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_17 PF13207.1 KKK23443.1 - 0.031 15.0 0.0 0.68 10.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KKK23443.1 - 0.057 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain UvrD_C_2 PF13538.1 KKK23443.1 - 0.071 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 KKK23443.1 - 0.072 12.8 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KKK23443.1 - 0.076 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 KKK23443.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 KKK23443.1 - 0.21 11.7 0.0 0.66 10.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 KKK23443.1 - 0.24 10.8 0.0 0.49 9.8 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PIF1 PF05970.9 KKK23443.1 - 0.25 10.2 0.0 8.6 5.1 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase efThoc1 PF11957.3 KKK23444.1 - 7.3e-180 598.6 5.4 9.5e-180 598.2 3.8 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor zf-RING_2 PF13639.1 KKK23473.1 - 1.9e-05 24.4 1.2 3.3e-05 23.6 0.9 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 KKK23473.1 - 0.0016 18.1 0.9 0.0028 17.3 0.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 KKK23473.1 - 0.0021 17.7 1.0 0.0036 17.0 0.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 KKK23473.1 - 0.012 15.4 0.2 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.2 KKK23473.1 - 0.072 13.2 2.2 0.14 12.2 1.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger PHD PF00628.24 KKK23473.1 - 0.11 12.1 1.2 0.22 11.2 0.8 1.5 1 0 0 1 1 1 0 PHD-finger Pol_alpha_B_N PF08418.5 KKK23473.1 - 4.6 6.6 9.0 10 5.5 0.0 2.7 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal R3H PF01424.17 KKK23474.1 - 9.4e-10 38.0 0.1 2.1e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 R3H domain SelP_N PF04592.9 KKK23474.1 - 0.17 11.2 15.2 0.38 10.1 10.5 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 KKK23474.1 - 0.34 9.8 6.0 0.66 8.9 4.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter EBV-NA3 PF05009.7 KKK23474.1 - 1.3 8.2 4.9 2.4 7.3 3.4 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Trypan_PARP PF05887.6 KKK23474.1 - 3.1 7.5 17.1 0.46 10.2 8.1 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ATP11 PF06644.6 KKK23475.1 - 3.7e-89 298.7 0.0 4.3e-89 298.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein zf-C4H2 PF10146.4 KKK23475.1 - 0.27 11.2 4.9 0.27 11.2 2.4 1.6 1 1 1 2 2 2 0 Zinc finger-containing protein CAP_N PF01213.14 KKK23475.1 - 1.1 8.5 8.7 1.8 7.7 6.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 KKK23475.1 - 6.3 6.0 13.5 7.9 5.7 8.3 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator Evr1_Alr PF04777.8 KKK23476.1 - 9.8e-27 92.7 0.0 2.9e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 Erv1 / Alr family zf-LYAR PF08790.6 KKK23476.1 - 4.4e-13 48.6 3.2 4.4e-13 48.6 2.2 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger MFS_1 PF07690.11 KKK23477.1 - 1.5e-17 63.4 56.4 1.2e-16 60.4 35.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2976 PF11190.3 KKK23477.1 - 0.00027 20.4 4.7 0.0018 17.7 0.3 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2976) Na_Pi_cotrans PF02690.10 KKK23477.1 - 0.78 9.4 14.5 0.84 9.3 1.1 3.9 3 1 1 4 4 4 0 Na+/Pi-cotransporter MFS_1 PF07690.11 KKK23478.1 - 2.3e-20 72.6 34.8 6.6e-20 71.1 22.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HAD PF12710.2 KKK23479.1 - 1.5e-09 38.2 0.0 2.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KKK23479.1 - 4.5e-06 25.9 0.0 0.035 13.2 0.0 2.0 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.21 KKK23479.1 - 0.013 15.9 0.1 0.22 11.9 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 KKK23480.1 - 3.9e-25 88.3 26.1 2.8e-13 49.3 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK23480.1 - 2.2e-07 29.6 8.9 0.00026 19.5 0.1 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KKK23480.1 - 5.4e-06 25.2 8.6 8.5e-06 24.6 6.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter AA_permease_2 PF13520.1 KKK23482.1 - 2.5e-66 223.9 40.5 3.1e-66 223.6 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK23482.1 - 8.2e-24 83.7 35.7 1.1e-23 83.3 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 KKK23483.1 - 1.4e-66 224.8 0.0 1.9e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2150 PF09920.4 KKK23483.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Sigma70_ECF PF07638.6 KKK23484.1 - 0.044 13.4 3.1 0.096 12.3 2.2 1.5 1 0 0 1 1 1 0 ECF sigma factor DUF3824 PF12868.2 KKK23484.1 - 1 10.2 6.9 0.26 12.2 0.7 2.5 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) D-ser_dehydrat PF14031.1 KKK23485.1 - 4.3e-20 71.6 0.0 1.1e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KKK23485.1 - 1.1e-11 44.7 0.1 1.8e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TauD PF02668.11 KKK23486.1 - 2.8e-24 86.1 0.0 4e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mucin PF01456.12 KKK23486.1 - 2.2 8.0 16.5 3.3 7.4 11.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 KKK23486.1 - 2.7 5.6 3.2 3.7 5.1 2.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TGF_beta_GS PF08515.7 KKK23487.1 - 2.2 7.7 5.3 4.1 6.8 3.7 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif adh_short PF00106.20 KKK23488.1 - 2.5e-24 86.0 3.2 3.8e-24 85.4 2.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK23488.1 - 1.3e-15 57.8 0.0 1.8e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK23488.1 - 1.6e-07 31.1 1.0 2.5e-07 30.5 0.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK23488.1 - 1.3e-06 28.5 0.7 3e-06 27.3 0.4 1.7 1 1 1 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 KKK23488.1 - 0.0014 17.8 0.0 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 KKK23488.1 - 0.038 12.8 0.1 0.063 12.1 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 KKK23488.1 - 0.039 13.3 0.4 0.062 12.7 0.3 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 KKK23488.1 - 0.11 12.0 0.4 0.21 11.1 0.3 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Zn_clus PF00172.13 KKK23489.1 - 1.5e-10 40.8 19.2 5e-06 26.3 7.6 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK23489.1 - 3.3e-10 39.2 0.0 3e-09 36.1 0.0 2.2 2 1 1 3 3 3 1 Fungal specific transcription factor domain Opy2 PF09463.5 KKK23489.1 - 7 6.8 14.5 9.8 6.3 5.6 2.5 2 0 0 2 2 2 0 Opy2 protein K_trans PF02705.11 KKK23490.1 - 9.8e-179 595.1 19.1 1.2e-178 594.8 13.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter PaaX PF07848.7 KKK23491.1 - 0.071 13.1 0.1 1.9 8.5 0.0 2.2 1 1 1 2 2 2 0 PaaX-like protein GntR PF00392.16 KKK23491.1 - 0.08 12.3 0.3 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family eIF2A PF08662.6 KKK23492.1 - 3.6e-40 137.7 4.3 3.2e-38 131.3 0.6 4.2 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 KKK23492.1 - 2.3e-07 30.5 0.0 5.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK23492.1 - 3.4e-07 29.8 0.0 9.3e-07 28.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK23492.1 - 2.4e-06 27.4 0.0 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KKK23492.1 - 8.1e-05 22.3 0.0 0.081 12.8 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-C3HC4_3 PF13920.1 KKK23493.1 - 1.9e-05 24.2 9.5 1.9e-05 24.2 6.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.13 KKK23494.1 - 5.9e-23 80.3 0.2 2.2e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 KKK23494.1 - 7e-16 57.7 0.1 1.6e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 DEK C terminal domain Herpes_LMP2 PF07415.6 KKK23494.1 - 2 6.9 4.4 2.6 6.5 3.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein WD40 PF00400.27 KKK23495.1 - 1.4e-81 265.6 23.3 1.4e-13 50.1 0.1 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KKK23495.1 - 2.8e-10 40.2 0.2 0.0042 16.8 0.0 3.7 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KKK23495.1 - 1.2e-08 33.5 7.2 0.13 10.3 0.1 5.5 3 2 3 6 6 6 4 Nucleoporin Nup120/160 NLE PF08154.7 KKK23495.1 - 7.3e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 KKK23495.1 - 0.0082 16.0 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain MutS_V PF00488.16 KKK23496.1 - 3.3e-75 252.5 0.4 6e-75 251.6 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KKK23496.1 - 3e-35 121.8 3.3 3e-35 121.8 2.3 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KKK23496.1 - 1.1e-13 51.1 0.3 2.9e-13 49.7 0.1 1.9 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 KKK23496.1 - 8.5e-11 42.0 0.3 2.4e-10 40.5 0.2 1.8 1 0 0 1 1 1 1 MutS domain II Response_reg PF00072.19 KKK23497.1 - 2.1e-21 76.0 0.3 4.8e-21 74.8 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KKK23497.1 - 3.8e-18 65.2 0.1 7.1e-18 64.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KKK23497.1 - 2.1e-13 50.0 0.2 5.3e-13 48.7 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KKK23497.1 - 0.00035 20.6 0.0 0.38 10.8 0.0 2.8 3 0 0 3 3 3 2 GAF domain ABC2_membrane PF01061.19 KKK23498.1 - 1.8e-86 288.6 51.0 2.6e-47 160.7 13.5 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KKK23498.1 - 2.3e-40 138.0 0.0 4e-19 69.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KKK23498.1 - 5.6e-23 80.5 0.1 5.6e-23 80.5 0.0 3.4 4 0 0 4 4 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KKK23498.1 - 1.3e-10 40.8 35.4 3.5e-08 32.8 12.3 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 KKK23498.1 - 2.7e-07 30.7 0.1 5.1e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KKK23498.1 - 1.5e-05 25.0 0.0 1.1 9.1 0.0 3.3 2 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KKK23498.1 - 6.4e-05 23.1 0.0 0.012 15.7 0.0 2.9 3 1 0 3 3 2 1 AAA domain UPF0079 PF02367.12 KKK23498.1 - 0.00029 20.4 0.1 0.065 12.8 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KKK23498.1 - 0.0005 20.3 0.0 0.023 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KKK23498.1 - 0.00066 19.1 0.0 0.1 12.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 KKK23498.1 - 0.0021 17.2 0.0 0.013 14.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KKK23498.1 - 0.0044 16.5 0.1 0.052 13.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KKK23498.1 - 0.0047 16.7 0.0 0.068 13.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 KKK23498.1 - 0.006 15.8 0.0 3.2 6.9 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KKK23498.1 - 0.0074 17.1 0.0 0.061 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK23498.1 - 0.0088 15.5 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 KKK23498.1 - 0.0095 15.9 0.1 0.037 13.9 0.1 2.0 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 KKK23498.1 - 0.014 15.1 0.0 3.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 KKK23498.1 - 0.016 14.9 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 KKK23498.1 - 0.021 14.2 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KKK23498.1 - 0.031 13.9 0.4 1.6 8.3 0.1 3.1 3 0 0 3 3 3 0 NACHT domain SbcCD_C PF13558.1 KKK23498.1 - 0.04 13.8 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 KKK23498.1 - 0.068 11.9 0.0 0.17 10.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 KKK23498.1 - 0.07 13.6 0.0 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 KKK23498.1 - 0.075 12.9 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Sugar_tr PF00083.19 KKK23500.1 - 8.4e-75 252.0 15.9 1e-74 251.7 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK23500.1 - 8e-17 60.9 24.7 8e-17 60.9 17.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KKK23501.1 - 9.8e-09 34.4 2.3 1.7e-08 33.6 0.2 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23501.1 - 1.3e-08 34.6 13.3 2.5e-08 33.7 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PFK PF00365.15 KKK23502.1 - 9.2e-167 553.0 1.8 2.4e-120 400.7 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 KKK23502.1 - 0.0051 15.6 0.1 1.1 7.9 0.0 2.3 2 0 0 2 2 2 2 ATP-NAD kinase DUF4646 PF15496.1 KKK23502.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) DUF4646 PF15496.1 KKK23503.1 - 3.9e-18 65.6 0.0 7.4e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF1049 PF06305.6 KKK23503.1 - 0.053 13.0 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF1191 PF06697.7 KKK23503.1 - 0.11 11.3 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) ISN1 PF06437.6 KKK23504.1 - 2e-194 645.9 0.0 2.2e-194 645.8 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Tyr-DNA_phospho PF06087.7 KKK23506.1 - 3e-76 256.8 0.0 5.6e-59 199.9 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 KKK23506.1 - 0.00014 21.1 7.7 0.0071 15.8 0.7 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif PDR_CDR PF06422.7 KKK23507.1 - 0.016 14.8 2.2 0.025 14.2 1.3 1.5 1 1 0 1 1 1 0 CDR ABC transporter PUF PF00806.14 KKK23508.1 - 2.9e-66 215.3 14.4 8.5e-10 37.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat cwf21 PF08312.7 KKK23509.1 - 5.2e-19 67.8 13.2 5.2e-19 67.8 9.2 2.7 1 1 1 2 2 2 1 cwf21 domain HA2 PF04408.18 KKK23510.1 - 2e-20 72.6 0.8 6.5e-20 71.0 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK23510.1 - 1.7e-14 53.4 0.0 1.4e-13 50.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KKK23510.1 - 1.6e-09 37.5 0.0 4.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KKK23510.1 - 6.7e-09 35.4 0.3 2.2e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK23510.1 - 0.00026 21.1 1.3 0.0048 17.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KKK23510.1 - 0.0041 16.0 0.0 0.0096 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KKK23510.1 - 0.061 13.1 0.0 0.33 10.7 0.0 3.5 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit Phage_G PF02306.10 KKK23510.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) F-box PF00646.28 KKK23511.1 - 0.0045 16.5 0.6 14 5.4 0.0 3.7 3 0 0 3 3 3 2 F-box domain LRR_4 PF12799.2 KKK23511.1 - 0.021 14.4 0.1 0.58 9.8 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Cytokin_check_N PF10407.4 KKK23511.1 - 0.031 13.8 0.2 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Glyco_transf_11 PF01531.11 KKK23511.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 F-box-like PF12937.2 KKK23511.1 - 8.4 6.2 17.1 85 2.9 0.0 3.4 3 1 0 3 3 3 0 F-box-like Glyco_hydro_3 PF00933.16 KKK23512.1 - 2.4e-91 305.8 0.0 3.4e-91 305.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK23512.1 - 1.7e-51 174.9 0.1 8.6e-51 172.6 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK23512.1 - 1.8e-20 72.6 0.0 4.8e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_1 PF00170.16 KKK23512.1 - 3.9e-07 29.9 9.9 7.4e-07 29.0 6.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK23512.1 - 0.0086 15.8 12.4 0.016 15.0 8.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HALZ PF02183.13 KKK23512.1 - 0.025 14.2 0.4 0.052 13.2 0.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Tmemb_cc2 PF10267.4 KKK23512.1 - 0.056 12.0 4.1 0.089 11.3 2.8 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein bZIP_Maf PF03131.12 KKK23512.1 - 0.12 12.6 7.3 0.22 11.8 5.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor AAA_13 PF13166.1 KKK23512.1 - 0.18 10.2 2.5 0.28 9.5 1.7 1.1 1 0 0 1 1 1 0 AAA domain ATPase_gene1 PF09527.5 KKK23513.1 - 0.11 12.3 0.2 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF1212 PF06738.7 KKK23514.1 - 1.5e-53 181.1 5.3 1.6e-48 164.7 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KKK23514.1 - 4.1e-27 94.6 7.6 4.1e-27 94.6 5.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) MRAP PF15183.1 KKK23516.1 - 0.041 13.4 1.4 0.1 12.2 1.0 1.7 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family COX14 PF14880.1 KKK23516.1 - 9.7 5.9 8.1 3.2 7.4 0.8 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Abhydrolase_5 PF12695.2 KKK23517.1 - 4.5e-13 49.1 0.0 8.3e-13 48.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK23517.1 - 7.1e-10 39.1 0.0 9.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KKK23517.1 - 3.5e-05 23.1 0.0 0.00018 20.8 0.0 2.0 2 1 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 KKK23517.1 - 0.00039 19.0 0.1 0.0013 17.3 0.1 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KKK23517.1 - 0.00059 19.5 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KKK23517.1 - 0.012 14.8 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Acyl_transf_2 PF02273.10 KKK23517.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase Transketolase_N PF00456.16 KKK23518.1 - 2.2e-15 56.2 0.5 3.3e-14 52.4 0.3 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 KKK23518.1 - 5.3e-07 29.5 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 KKK23518.1 - 3.3e-05 23.4 1.1 0.00024 20.6 0.1 2.3 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 KKK23518.1 - 0.0046 16.5 0.7 0.022 14.3 0.5 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KKK23518.1 - 0.048 12.3 0.0 0.09 11.4 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component Histone PF00125.19 KKK23520.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KKK23520.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KKK23520.1 - 0.0035 17.3 0.3 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KKK23520.1 - 0.04 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 KKK23521.1 - 3.1e-15 56.0 0.4 4.6e-15 55.4 0.1 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KKK23521.1 - 0.00021 21.1 0.1 0.00031 20.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KKK23521.1 - 0.00026 21.1 0.1 0.00038 20.5 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KKK23521.1 - 0.00037 20.4 0.0 0.00065 19.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KKK23521.1 - 0.034 13.8 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KKK23521.1 - 0.043 13.0 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T MFS_1 PF07690.11 KKK23522.1 - 9.4e-41 139.6 53.8 9.4e-41 139.6 37.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK23522.1 - 8.7e-05 21.2 16.3 8.7e-05 21.2 11.3 4.0 2 2 3 5 5 5 2 Sugar (and other) transporter Keratin_assoc PF09775.4 KKK23522.1 - 0.004 16.6 3.1 0.004 16.6 2.2 2.6 2 0 0 2 2 2 1 Keratinocyte-associated protein 2 TPR_19 PF14559.1 KKK23523.1 - 1.2e-05 25.5 2.2 0.17 12.2 0.0 2.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK23523.1 - 4.7e-05 23.9 0.4 0.0034 18.0 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK23523.1 - 0.00016 21.2 0.2 0.67 9.6 0.0 2.7 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.1 KKK23523.1 - 0.00052 19.8 2.8 0.01 15.6 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK23523.1 - 0.0012 19.2 2.0 0.15 12.7 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK23523.1 - 0.0033 17.3 0.0 0.02 14.8 0.0 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KKK23523.1 - 0.0037 17.3 0.0 0.56 10.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Vps39_1 PF10366.4 KKK23523.1 - 0.066 13.2 1.9 0.12 12.4 0.2 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Apc3 PF12895.2 KKK23523.1 - 0.098 12.8 0.0 0.3 11.2 0.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KKK23523.1 - 0.11 12.4 1.1 57 3.9 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2457 PF10446.4 KKK23523.1 - 7.6 5.1 9.8 11 4.5 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UQ_con PF00179.21 KKK23524.1 - 2.3e-16 59.4 0.0 2.6e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SKI PF01202.17 KKK23525.1 - 0.00056 19.8 0.0 0.00064 19.6 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 KKK23525.1 - 0.0016 18.3 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2338 PF10100.4 KKK23525.1 - 0.012 14.0 0.0 0.014 13.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) IPPT PF01715.12 KKK23525.1 - 0.042 12.8 0.0 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 IPP transferase Sec7_N PF12783.2 KKK23526.1 - 1.3e-43 148.3 3.2 5.1e-43 146.4 0.1 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal NAD_binding_1 PF00175.16 KKK23542.1 - 7.2e-33 113.4 0.0 1.2e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KKK23542.1 - 2.3e-20 72.5 0.0 6e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KKK23542.1 - 2.5e-08 33.9 0.0 0.00039 20.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ribosomal_L18ae PF01775.12 KKK23543.1 - 2.9e-60 201.5 0.3 3.7e-60 201.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain zf-Tim10_DDP PF02953.10 KKK23544.1 - 4.1e-26 90.0 1.2 4.8e-26 89.8 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CLTH PF10607.4 KKK23545.1 - 9.4e-32 109.7 0.1 8.6e-31 106.5 0.0 2.3 1 1 1 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KKK23545.1 - 9e-18 63.7 5.3 1.5e-17 63.0 2.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 KKK23545.1 - 3.5e-05 23.5 2.3 6.5e-05 22.6 1.6 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 KKK23545.1 - 3.7e-05 23.0 0.1 3.7e-05 23.0 0.0 2.5 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_5 PF14634.1 KKK23545.1 - 0.00075 19.1 2.2 0.0014 18.3 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KKK23545.1 - 0.0024 17.8 3.2 0.0046 16.9 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK23545.1 - 0.0083 15.7 2.6 0.014 15.0 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Corona_S2 PF01601.11 KKK23545.1 - 0.021 12.9 0.8 0.033 12.3 0.6 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein zf-C3HC4 PF00097.20 KKK23545.1 - 0.14 11.8 4.0 0.28 10.8 2.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KKK23545.1 - 0.27 11.1 3.2 0.59 10.0 2.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Syntaxin PF00804.20 KKK23545.1 - 1.9 8.6 9.0 0.061 13.4 1.2 2.2 2 2 0 2 2 2 0 Syntaxin PG_binding_1 PF01471.13 KKK23546.1 - 0.039 13.9 0.0 8.7 6.4 0.0 3.2 3 0 0 3 3 3 0 Putative peptidoglycan binding domain PCI PF01399.22 KKK23547.1 - 3.9e-09 36.7 0.0 8.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.9 KKK23547.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) BTB PF00651.26 KKK23548.1 - 1.4e-05 25.0 0.0 8.3e-05 22.5 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain S1 PF00575.18 KKK23556.1 - 1.4e-76 252.5 26.3 1.7e-14 53.6 0.5 12.0 12 0 0 12 12 12 11 S1 RNA binding domain TPR_16 PF13432.1 KKK23556.1 - 2.9e-08 34.1 0.0 0.012 16.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK23556.1 - 2.7e-07 30.8 0.2 0.11 12.8 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK23556.1 - 1.1e-06 28.7 0.3 0.78 10.5 0.3 4.9 2 2 3 5 5 5 1 Tetratricopeptide repeat Suf PF05843.9 KKK23556.1 - 1.3e-05 25.1 0.7 0.068 12.8 0.1 3.5 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 KKK23556.1 - 0.0018 17.8 0.1 2.9 7.5 0.0 2.6 2 0 0 2 2 2 2 TPR repeat PPR PF01535.15 KKK23556.1 - 0.0068 16.3 0.1 2.2 8.4 0.0 3.4 3 0 0 3 3 3 1 PPR repeat TPR_12 PF13424.1 KKK23556.1 - 0.0086 15.9 0.3 3.7 7.5 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK23556.1 - 0.02 14.6 3.5 0.9 9.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK23556.1 - 0.079 12.9 1.3 6.8 6.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KKK23556.1 - 0.085 11.9 0.5 0.29 10.1 0.3 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK23556.1 - 0.18 12.3 2.0 1.2e+02 3.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SDA1 PF05285.7 KKK23556.1 - 1 8.5 26.5 0.03 13.6 10.6 2.7 2 0 0 2 2 2 0 SDA1 UreD PF01774.12 KKK23557.1 - 2.9e-51 173.9 0.0 3.8e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein tRNA-synt_2b PF00587.20 KKK23559.1 - 4.2e-22 78.5 0.1 6.1e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KKK23559.1 - 1.6e-11 43.9 0.0 3.9e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.6 KKK23559.1 - 7.5e-09 35.3 0.0 2e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal DUF1497 PF07384.6 KKK23559.1 - 0.075 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) WD40 PF00400.27 KKK23561.1 - 4.8e-23 80.1 2.6 3.6e-05 23.4 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 KKK23562.1 - 1.9e-142 475.3 14.5 2.1e-142 475.1 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family STAG PF08514.6 KKK23563.1 - 6.3e-38 129.1 0.5 1.6e-37 127.8 0.4 1.7 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 KKK23563.1 - 7.5e-05 22.9 1.0 0.06 13.6 0.0 4.3 4 1 0 4 4 4 1 HEAT repeats FlgM PF04316.8 KKK23563.1 - 0.00011 22.0 3.0 0.0019 18.1 1.4 3.1 3 0 0 3 3 3 1 Anti-sigma-28 factor, FlgM HEAT PF02985.17 KKK23563.1 - 0.0081 16.1 0.0 47 4.4 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Nop14 PF04147.7 KKK23563.1 - 1.8 6.3 35.0 0.13 10.1 9.0 2.9 3 0 0 3 3 3 0 Nop14-like family Daxx PF03344.10 KKK23563.1 - 5.1 5.4 32.4 0.15 10.5 5.0 2.6 2 0 0 2 2 2 0 Daxx Family Y_phosphatase3 PF13350.1 KKK23565.1 - 8.2e-37 126.9 0.0 1.1e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KKK23565.1 - 1.1e-10 41.4 0.0 2.8e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KKK23565.1 - 0.0021 17.4 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KKK23565.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KKK23565.1 - 0.057 13.4 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.9 KKK23565.1 - 0.19 10.4 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Mucin PF01456.12 KKK23594.1 - 1.5 8.5 10.4 3.2 7.5 7.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein RabGAP-TBC PF00566.13 KKK23595.1 - 4.3e-41 140.7 0.6 7.4e-41 139.9 0.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KKK23595.1 - 7.5e-13 48.2 0.0 3.4e-08 33.0 0.0 3.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) Ring_hydroxyl_A PF00848.14 KKK23596.1 - 3.5e-27 95.4 3.6 3.5e-26 92.1 2.5 2.0 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KKK23597.1 - 1.8e-15 56.2 0.1 3.7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 KKK23597.1 - 6.5e-08 32.4 0.0 0.00012 21.7 0.0 2.5 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) WD40 PF00400.27 KKK23633.1 - 0.094 12.6 10.6 7.9 6.5 1.6 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat Daxx PF03344.10 KKK23633.1 - 4.5 5.6 13.2 7.2 4.9 9.1 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KKK23633.1 - 6.3 4.5 13.7 10 3.8 9.5 1.2 1 0 0 1 1 1 0 Nop14-like family Vps35 PF03635.12 KKK23634.1 - 0 1019.6 0.2 0 1019.4 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TerB-C PF15615.1 KKK23634.1 - 0.0058 16.8 2.2 0.11 12.7 1.1 2.6 2 0 0 2 2 2 1 TerB-C domain DUF3907 PF13047.1 KKK23634.1 - 0.033 13.8 0.0 5.3 6.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) Cyt-b5 PF00173.23 KKK23635.1 - 2.4e-05 24.0 0.0 2.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ish1 PF10281.4 KKK23636.1 - 5.3e-83 272.6 9.5 9.6e-12 44.7 0.0 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.22 KKK23636.1 - 1.9e-10 39.9 0.0 0.63 9.6 0.0 6.4 5 2 0 5 5 5 3 SAP domain HeH PF12949.2 KKK23636.1 - 2.3e-10 39.8 0.0 0.15 11.6 0.1 5.9 6 0 0 6 6 6 3 HeH/LEM domain Slx4 PF09494.5 KKK23636.1 - 5.9e-06 25.9 0.8 9.8 6.0 0.0 5.6 5 0 0 5 5 5 1 Slx4 endonuclease APC2 PF08672.6 KKK23636.1 - 3.3e-05 24.0 4.6 7 6.9 0.0 6.6 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 LEM PF03020.10 KKK23636.1 - 0.022 14.2 0.0 35 3.9 0.0 4.5 6 0 0 6 6 6 0 LEM domain Amidase02_C PF12123.3 KKK23636.1 - 0.025 14.2 0.1 6 6.6 0.2 3.7 3 0 0 3 3 3 0 N-acetylmuramoyl-l-alanine amidase SAM_2 PF07647.12 KKK23636.1 - 0.16 11.8 8.9 13 5.7 0.0 5.8 6 1 1 7 7 7 0 SAM domain (Sterile alpha motif) Apolipoprotein PF01442.13 KKK23636.1 - 0.3 10.5 4.8 1.3 8.4 1.4 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1470 PF07336.6 KKK23636.1 - 1.4 9.2 27.9 1.9 8.8 1.6 5.6 5 1 0 5 5 5 0 Protein of unknown function (DUF1470) PQ-loop PF04193.9 KKK23637.1 - 1.4e-20 72.5 14.8 7.1e-12 44.7 3.6 3.6 3 1 1 4 4 4 2 PQ loop repeat LtrA PF06772.6 KKK23637.1 - 0.036 12.9 1.2 0.052 12.4 0.4 1.6 1 1 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) CTV_P6 PF06706.6 KKK23637.1 - 0.15 11.5 2.9 0.74 9.3 0.3 2.6 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein NTF2 PF02136.15 KKK23638.1 - 7.9e-31 106.8 0.0 1.1e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Surp PF01805.15 KKK23639.1 - 3.6e-17 61.7 0.0 6.6e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Surp module DUF3169 PF11368.3 KKK23641.1 - 0.37 9.9 0.1 0.56 9.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Glycos_transf_2 PF00535.21 KKK23642.1 - 4.7e-34 117.4 0.0 6e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KKK23642.1 - 1.2e-14 54.6 0.0 1.8e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KKK23642.1 - 1.9e-07 30.4 0.0 2.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KKK23642.1 - 0.00026 20.3 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 KKK23642.1 - 0.01 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 KKK23642.1 - 0.098 12.9 0.0 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF1749 PF08538.5 KKK23643.1 - 7.1e-108 360.0 0.0 8.2e-108 359.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KKK23643.1 - 6.7e-07 29.4 0.5 2.5e-06 27.5 0.3 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK23643.1 - 0.00013 21.7 0.0 0.00081 19.1 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KKK23643.1 - 0.00054 19.4 0.0 0.17 11.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 KKK23643.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.3 KKK23643.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 KKK23643.1 - 0.14 11.3 0.0 0.34 10.1 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ras PF00071.17 KKK23648.1 - 4.1e-51 172.5 0.6 2.8e-50 169.8 0.4 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK23648.1 - 6e-16 59.0 0.2 1.6e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KKK23648.1 - 0.00069 18.9 0.1 0.0035 16.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KKK23648.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK23648.1 - 0.025 13.8 0.2 0.42 9.8 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_25 PF13481.1 KKK23648.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ser_hydrolase PF06821.8 KKK23648.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase SRPRB PF09439.5 KKK23648.1 - 0.1 11.7 0.0 0.54 9.4 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.13 KKK23648.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin HAD_2 PF13419.1 KKK23649.1 - 2e-25 90.0 0.1 5.8e-25 88.5 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK23649.1 - 3.7e-07 30.7 0.0 4.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK23649.1 - 0.00019 21.0 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Gluconate_2-dh3 PF13618.1 KKK23649.1 - 0.13 12.4 0.1 0.67 10.1 0.0 2.1 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Fungal_trans PF04082.13 KKK23650.1 - 4.6e-07 28.9 0.0 7.6e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ras PF00071.17 KKK23651.1 - 3.6e-55 185.7 0.0 4.1e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK23651.1 - 7.1e-18 65.2 0.0 9.8e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK23651.1 - 2.3e-07 30.2 0.0 3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK23651.1 - 0.0071 15.7 0.0 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.17 KKK23652.1 - 2.8e-15 55.6 0.0 7.7e-15 54.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK23652.1 - 1.1e-09 38.1 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.6 KKK23652.1 - 4.4 7.0 57.5 5.2 6.8 36.4 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DUF966 PF06136.8 KKK23652.1 - 9 5.6 31.1 2.5 7.4 18.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF966) POT1 PF02765.12 KKK23660.1 - 1.4e-19 70.4 0.0 5.6e-19 68.5 0.0 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Arm PF00514.18 KKK23661.1 - 1e-93 304.3 10.2 3.6e-14 51.9 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KKK23661.1 - 1.9e-24 85.7 0.1 4.6e-10 39.6 0.0 5.7 1 1 6 7 7 7 4 HEAT repeats IBB PF01749.15 KKK23661.1 - 2.2e-21 75.8 3.9 4.2e-21 74.9 2.7 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 KKK23661.1 - 4.7e-21 72.9 0.1 1.1e-06 28.1 0.0 7.0 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 KKK23661.1 - 1.8e-20 72.7 8.8 4.4e-10 39.7 0.1 6.0 5 1 2 7 7 7 3 HEAT-like repeat Arm_2 PF04826.8 KKK23661.1 - 7.2e-12 44.9 0.0 0.00079 18.6 0.0 4.4 3 1 2 5 5 5 3 Armadillo-like Adaptin_N PF01602.15 KKK23661.1 - 1.6e-06 26.7 0.0 0.00034 19.0 0.0 2.3 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 KKK23661.1 - 5.7e-05 23.0 0.0 0.61 10.0 0.0 4.5 3 2 2 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KKK23661.1 - 0.0024 16.2 0.0 0.74 8.0 0.0 3.0 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KKK23661.1 - 0.0076 16.6 4.7 0.64 10.6 0.0 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Glycos_trans_3N PF02885.12 KKK23661.1 - 0.023 14.2 0.0 31 4.2 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Mo25 PF08569.6 KKK23661.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Mo25-like TRAP_alpha PF03896.11 KKK23662.1 - 1.1e-11 44.2 2.7 3.5e-11 42.6 1.9 1.7 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Haemadin PF09065.5 KKK23663.1 - 0.028 13.9 4.7 3.6 7.2 0.1 3.0 2 1 0 2 2 2 0 Haemadin HA2 PF04408.18 KKK23664.1 - 3.1e-19 68.8 0.0 1e-18 67.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) RWD PF05773.17 KKK23664.1 - 1.8e-12 47.1 0.2 4.9e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 RWD domain Helicase_C PF00271.26 KKK23664.1 - 3.6e-12 45.9 0.0 1.2e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KKK23664.1 - 3.9e-10 39.5 0.0 8e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KKK23664.1 - 8e-10 38.4 0.1 1.5e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KKK23664.1 - 0.00035 19.5 0.0 0.00072 18.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KKK23664.1 - 0.00042 20.4 0.9 0.0016 18.5 0.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KKK23664.1 - 0.0029 17.0 0.0 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 KKK23664.1 - 0.014 14.5 0.1 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KKK23664.1 - 0.014 14.7 0.0 0.22 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DND1_DSRM PF14709.1 KKK23664.1 - 0.031 14.5 0.4 0.11 12.8 0.3 2.0 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Zot PF05707.7 KKK23664.1 - 0.036 13.5 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PhoH PF02562.11 KKK23664.1 - 0.042 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 KKK23664.1 - 0.094 13.0 0.9 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Podovirus_Gp16 PF05894.7 KKK23664.1 - 0.22 10.8 0.0 0.45 9.7 0.0 1.4 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) DcpS_C PF11969.3 KKK23665.1 - 8.9e-16 58.1 5.2 8.2e-15 55.0 3.6 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KKK23665.1 - 1.4e-15 57.5 0.0 3.3e-15 56.3 0.0 1.6 1 1 0 1 1 1 1 HIT domain Pkinase PF00069.20 KKK23666.1 - 8e-19 67.7 0.0 1.9e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23666.1 - 3.4e-08 32.8 0.0 1.1e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3433 PF11915.3 KKK23666.1 - 0.03 14.4 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) Peptidase_M49 PF03571.10 KKK23668.1 - 3.5e-233 774.6 0.0 4.4e-233 774.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 SNF5 PF04855.7 KKK23668.1 - 1.5e-89 299.6 0.0 2.4e-89 298.9 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF3609 PF12259.3 KKK23669.1 - 0.076 11.6 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) ABC_tran PF00005.22 KKK23670.1 - 3.1e-48 163.5 0.6 3.5e-23 82.4 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KKK23670.1 - 8.4e-21 73.6 8.1 8.4e-21 73.6 5.6 3.9 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 KKK23670.1 - 1.5e-15 57.9 0.1 0.0026 17.7 0.0 4.7 5 0 0 5 5 4 3 AAA domain SMC_N PF02463.14 KKK23670.1 - 1.4e-10 40.7 1.0 0.025 13.7 0.0 4.6 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KKK23670.1 - 2.9e-09 37.7 0.4 0.0049 17.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 KKK23670.1 - 2.5e-06 27.4 0.0 0.019 14.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KKK23670.1 - 3.8e-06 26.1 0.1 0.013 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK23670.1 - 4.4e-06 26.8 0.9 0.0075 16.2 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KKK23670.1 - 6e-06 25.6 0.1 0.068 12.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KKK23670.1 - 9.2e-06 26.1 0.2 0.05 14.1 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_22 PF13401.1 KKK23670.1 - 2.1e-05 24.6 0.1 0.21 11.7 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KKK23670.1 - 2.1e-05 24.8 4.2 0.16 12.2 0.0 3.7 5 0 0 5 5 2 2 AAA domain AAA_23 PF13476.1 KKK23670.1 - 9.9e-05 22.7 17.5 0.019 15.2 0.0 4.9 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.1 KKK23670.1 - 0.00013 22.0 2.8 0.092 12.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 KKK23670.1 - 0.00024 20.8 0.1 0.7 9.5 0.1 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KKK23670.1 - 0.0003 20.6 0.1 0.95 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KKK23670.1 - 0.00033 20.5 4.4 0.23 11.2 0.0 3.9 4 0 0 4 4 3 1 Dynamin family NACHT PF05729.7 KKK23670.1 - 0.00085 19.0 0.1 0.6 9.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 KKK23670.1 - 0.0015 17.3 0.2 1.5 7.5 0.0 2.7 2 0 0 2 2 2 2 ArgK protein AAA PF00004.24 KKK23670.1 - 0.0018 18.4 0.1 1.6 8.9 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 KKK23670.1 - 0.0018 17.3 10.5 0.28 10.1 0.0 4.7 4 2 2 6 6 6 2 AAA ATPase domain AAA_14 PF13173.1 KKK23670.1 - 0.0043 16.9 0.0 6.4 6.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 KKK23670.1 - 0.0061 15.9 0.0 1.9 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KKK23670.1 - 0.0064 15.9 0.7 3.7 6.9 0.0 3.4 4 0 0 4 4 3 1 AAA-like domain RNA_helicase PF00910.17 KKK23670.1 - 0.0088 16.2 0.0 5.4 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.20 KKK23670.1 - 0.012 15.0 0.3 0.66 9.4 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 KKK23670.1 - 0.018 14.7 0.1 3.2 7.4 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 KKK23670.1 - 0.025 14.1 0.1 4.5 6.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KKK23670.1 - 0.027 13.9 0.0 9.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KKK23670.1 - 0.029 13.2 0.0 4.2 6.1 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 KKK23670.1 - 0.057 12.8 2.5 3 7.2 0.3 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KKK23670.1 - 0.057 13.1 0.4 7.9 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 KKK23670.1 - 0.06 13.2 3.1 8.9 6.3 0.1 3.5 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 KKK23670.1 - 1 9.1 8.5 8.6 6.1 0.0 4.1 5 0 0 5 5 4 0 Domain of unknown function DUF87 Sugar_tr PF00083.19 KKK23671.1 - 3.7e-50 170.8 16.7 6.2e-30 104.1 4.7 4.1 2 1 2 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.11 KKK23671.1 - 0.0028 16.4 31.0 0.0063 15.2 7.4 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Erythrovirus_X PF06795.6 KKK23671.1 - 0.019 15.0 0.6 0.4 10.7 0.0 2.4 2 0 0 2 2 2 0 Erythrovirus X protein WD40 PF00400.27 KKK23672.1 - 5.3e-51 168.7 24.3 4.5e-13 48.5 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KKK23672.1 - 1.1e-06 28.4 14.5 0.0095 15.6 2.1 4.1 2 2 3 5 5 5 3 Transcription factor IIIC subunit delta N-term SKG6 PF08693.5 KKK23673.1 - 0.064 12.5 0.9 0.12 11.7 0.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 KKK23673.1 - 0.25 11.0 0.0 0.44 10.2 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain MFS_1 PF07690.11 KKK23674.1 - 7.4e-43 146.5 30.5 7.4e-43 146.5 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK23674.1 - 1.8e-13 49.9 9.5 1.8e-13 49.9 6.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter RRN3 PF05327.6 KKK23697.1 - 7.1e-191 635.1 0.0 1.8e-190 633.8 0.0 1.6 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_3 PF07859.8 KKK23698.1 - 6.6e-45 153.2 3.4 1.1e-43 149.3 2.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK23698.1 - 2.7e-09 36.3 1.4 6.8e-09 34.9 1.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KKK23698.1 - 0.00018 21.2 0.0 0.00025 20.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KKK23698.1 - 0.023 13.9 0.7 0.12 11.6 0.2 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KKK23698.1 - 0.037 13.4 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.15 KKK23698.1 - 0.085 12.2 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 KKK23698.1 - 0.12 11.6 0.0 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.3 KKK23698.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) WD40 PF00400.27 KKK23699.1 - 4.7e-27 92.8 4.9 5.5e-07 29.2 0.1 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KKK23699.1 - 4.1e-05 21.9 0.9 0.011 13.8 0.1 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nop14 PF04147.7 KKK23699.1 - 3 5.6 26.0 5.3 4.8 18.0 1.3 1 0 0 1 1 1 0 Nop14-like family Fcf1 PF04900.7 KKK23701.1 - 1.8e-11 43.9 1.1 0.00017 21.6 0.1 3.1 3 1 0 3 3 3 2 Fcf1 Cmc1 PF08583.5 KKK23702.1 - 1.5e-16 59.8 5.1 1.8e-16 59.6 3.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Redoxin PF08534.5 KKK23711.1 - 1.3e-26 92.9 0.0 1.7e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KKK23711.1 - 5.5e-08 32.5 0.0 7.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.13 KKK23712.1 - 1.7e-22 79.1 0.0 2.9e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein Dak2 PF02734.12 KKK23712.1 - 0.046 13.3 0.1 0.055 13.1 0.1 1.1 1 0 0 1 1 1 0 DAK2 domain Ion_trans PF00520.26 KKK23713.1 - 4.6e-99 329.6 86.4 6.7e-35 120.1 4.3 5.5 6 0 0 6 6 6 4 Ion transport protein EF-hand_1 PF00036.27 KKK23713.1 - 0.0016 17.6 0.0 0.0045 16.2 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KKK23713.1 - 0.011 15.4 0.0 0.055 13.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 KKK23713.1 - 0.058 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair PAP1 PF08601.5 KKK23715.1 - 0.11 12.1 3.7 0.13 11.9 2.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 KH_1 PF00013.24 KKK23718.1 - 5.7e-25 86.7 2.4 6e-08 32.2 0.2 6.5 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 KKK23718.1 - 1.3e-18 66.1 2.0 0.00017 21.1 0.0 5.9 6 0 0 6 6 6 4 KH domain HATPase_c_5 PF14501.1 KKK23718.1 - 0.039 13.6 0.6 0.098 12.3 0.2 1.8 1 1 1 2 2 2 0 GHKL domain MRP-L28 PF09812.4 KKK23719.1 - 1.9e-07 31.0 0.2 3e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RINGv PF12906.2 KKK23719.1 - 3.9e-05 23.5 6.9 6.9e-05 22.8 4.8 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KKK23719.1 - 0.00016 21.5 3.3 0.00031 20.6 2.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 KKK23719.1 - 0.0039 16.9 5.3 0.0063 16.3 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain GalKase_gal_bdg PF10509.4 KKK23720.1 - 1.3e-19 69.1 0.1 2.3e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KKK23720.1 - 2.8e-15 56.1 0.8 9.2e-15 54.4 0.5 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KKK23720.1 - 4.2e-12 46.0 0.0 9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_37 PF13744.1 KKK23720.1 - 0.049 13.4 0.1 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.17 KKK23720.1 - 0.12 12.2 0.2 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix TPP_enzyme_N PF02776.13 KKK23721.1 - 1.1e-57 194.2 0.1 3e-56 189.6 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KKK23721.1 - 7.2e-50 168.5 0.1 1.1e-47 161.4 0.0 3.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KKK23721.1 - 3.1e-35 120.8 0.1 7.5e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 KKK23721.1 - 0.023 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Annexin PF00191.15 KKK23728.1 - 2.2e-48 161.9 0.6 3.3e-19 68.5 0.0 3.4 3 0 0 3 3 3 3 Annexin Glyco_hydro_61 PF03443.9 KKK23729.1 - 1.2e-62 211.6 0.0 1.2e-62 211.6 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KKK23729.1 - 7.4e-13 47.9 5.8 1.9e-12 46.5 4.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_transf_28 PF03033.15 KKK23730.1 - 1.2e-17 63.9 0.0 1.3e-16 60.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KKK23730.1 - 6.8e-06 24.9 0.0 1.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 KKK23730.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 ATG C terminal domain Glyco_tran_28_C PF04101.11 KKK23730.1 - 0.013 15.2 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Cation_efflux PF01545.16 KKK23731.1 - 4.3e-83 278.6 0.2 7.7e-83 277.8 0.2 1.4 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 KKK23731.1 - 0.00047 19.2 1.8 0.00047 19.2 1.2 1.7 2 1 0 2 2 2 1 ZIP Zinc transporter YpzI PF14140.1 KKK23732.1 - 0.2 11.1 0.6 22 4.6 0.0 2.3 2 0 0 2 2 2 0 YpzI-like protein PI-PLC-X PF00388.14 KKK23734.1 - 3.6e-59 198.3 0.0 6.3e-59 197.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KKK23734.1 - 4.5e-41 139.5 0.1 1.6e-39 134.5 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KKK23734.1 - 6.9e-05 22.7 0.0 0.00025 20.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 KKK23734.1 - 0.0027 17.2 0.0 0.0077 15.7 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.27 KKK23734.1 - 0.022 14.0 1.2 0.071 12.4 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 KKK23734.1 - 0.18 11.9 2.2 0.95 9.6 1.6 2.1 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KKK23734.1 - 0.31 11.0 2.8 2.2 8.4 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain WD40 PF00400.27 KKK23735.1 - 1.3e-14 53.4 12.0 1.3e-08 34.4 0.6 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KKK23735.1 - 0.0012 17.2 0.0 1.7 6.8 0.0 3.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain MRG PF05712.8 KKK23735.1 - 0.048 12.5 0.3 0.095 11.5 0.2 1.4 1 1 0 1 1 1 0 MRG DUF4613 PF15390.1 KKK23735.1 - 0.067 11.3 0.5 0.11 10.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) DUF3312 PF11768.3 KKK23735.1 - 0.093 10.9 0.0 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF1513 PF07433.6 KKK23735.1 - 0.094 11.5 0.4 0.6 8.9 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) DUF1308 PF07000.6 KKK23736.1 - 3.1e-103 345.1 0.0 8.1e-103 343.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) Allexi_40kDa PF05549.6 KKK23736.1 - 0.064 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Ribonuc_red_sm PF00268.16 KKK23737.1 - 6.6e-121 402.6 1.3 7.9e-121 402.3 0.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Mito_carr PF00153.22 KKK23738.1 - 2e-58 194.0 4.1 1.2e-20 73.0 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP9-21 PF05486.7 KKK23739.1 - 2.8e-32 110.2 0.2 3.7e-32 109.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pol_alpha_B_N PF08418.5 KKK23739.1 - 0.31 10.5 3.9 0.45 10.0 2.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal F-box-like PF12937.2 KKK23743.1 - 5.3e-10 38.8 1.4 3.6e-07 29.7 0.1 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 KKK23743.1 - 4.5e-07 29.3 0.6 0.016 14.8 0.0 2.7 2 0 0 2 2 2 2 F-box domain DAHP_synth_1 PF00793.15 KKK23744.1 - 5.9e-95 317.0 0.0 9.8e-95 316.3 0.0 1.2 1 0 0 1 1 1 1 DAHP synthetase I family EBP PF05241.7 KKK23744.1 - 2.4e-55 186.6 8.0 3.5e-55 186.0 5.5 1.2 1 0 0 1 1 1 1 Emopamil binding protein CorA PF01544.13 KKK23744.1 - 0.19 10.7 0.3 0.36 9.8 0.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Apolipoprotein PF01442.13 KKK23744.1 - 0.53 9.7 3.6 1.2 8.6 1.0 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain AIG2_2 PF13772.1 KKK23745.1 - 8.6e-05 22.5 0.7 0.00048 20.1 0.1 2.4 2 1 0 2 2 2 1 AIG2-like family Cytochrom_C1 PF02167.10 KKK23746.1 - 1.9e-80 269.6 0.0 2.4e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KKK23746.1 - 0.021 14.9 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Sec10 PF07393.6 KKK23747.1 - 1.5e-181 605.1 3.5 1.8e-181 604.9 2.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KKK23747.1 - 6.2e-05 22.6 0.1 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK23747.1 - 0.00098 18.7 0.1 0.0022 17.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain RINT1_TIP1 PF04437.8 KKK23747.1 - 0.0037 15.8 0.6 0.0066 15.0 0.1 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CAP PF00188.21 KKK23748.1 - 4.5e-20 72.3 5.4 6.2e-20 71.9 3.7 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAP2_3 PF14378.1 KKK23748.1 - 0.028 13.9 0.6 0.041 13.3 0.4 1.2 1 0 0 1 1 1 0 PAP2 superfamily Chromo PF00385.19 KKK23749.1 - 1.1e-08 34.6 0.5 3.3e-08 33.0 0.3 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DSRB PF10781.4 KKK23749.1 - 0.066 12.7 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Dextransucrase DSRB Mito_carr PF00153.22 KKK23750.1 - 6.8e-69 227.6 0.3 4.7e-22 77.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 KKK23750.1 - 0.0047 16.3 0.0 7.6 6.0 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1049) CRF PF00473.12 KKK23750.1 - 0.057 13.5 0.1 0.78 9.8 0.0 2.5 2 0 0 2 2 2 0 Corticotropin-releasing factor family SLX9 PF15341.1 KKK23751.1 - 1.3e-35 122.4 9.5 1.7e-35 122.0 6.6 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Neugrin PF06413.6 KKK23751.1 - 0.015 15.1 5.3 0.26 11.0 1.2 2.1 1 1 1 2 2 2 0 Neugrin HrpJ PF07201.6 KKK23751.1 - 0.064 13.2 2.7 0.13 12.2 1.9 1.5 1 1 0 1 1 1 0 HrpJ-like domain DUF2413 PF10310.4 KKK23751.1 - 0.13 11.0 5.6 0.15 10.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Calpain_inhib PF00748.14 KKK23751.1 - 0.37 11.1 5.9 0.22 11.8 2.2 1.8 1 1 1 2 2 2 0 Calpain inhibitor Brix PF04427.13 KKK23752.1 - 8.7e-30 103.8 0.0 2.2e-29 102.4 0.0 1.7 2 0 0 2 2 2 1 Brix domain F-box-like PF12937.2 KKK23752.1 - 0.00015 21.4 0.1 0.00034 20.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK23752.1 - 0.0027 17.3 0.5 0.0068 16.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain PBP1_TM PF14812.1 KKK23752.1 - 0.22 11.8 3.5 0.59 10.4 2.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_2 PF07724.9 KKK23753.1 - 1.9e-39 135.3 0.0 2e-38 132.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KKK23753.1 - 6.7e-15 55.4 0.0 1.4e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KKK23753.1 - 2.6e-08 33.6 0.0 7e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KKK23753.1 - 2.4e-06 27.3 0.0 5.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KKK23753.1 - 7.2e-05 22.3 0.0 0.022 14.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 KKK23753.1 - 0.00011 22.3 0.3 0.003 17.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK23753.1 - 0.00017 21.6 2.2 0.00045 20.2 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 KKK23753.1 - 0.0002 20.6 0.2 0.011 14.9 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KKK23753.1 - 0.0008 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KKK23753.1 - 0.0016 19.2 0.2 0.0037 18.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 KKK23753.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KKK23753.1 - 0.0038 16.2 0.6 0.074 12.0 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KKK23753.1 - 0.02 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KKK23753.1 - 0.022 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK23753.1 - 0.033 13.8 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KKK23753.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 KKK23753.1 - 0.063 12.8 0.0 0.17 11.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KKK23753.1 - 0.074 13.1 0.0 0.42 10.6 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 KKK23753.1 - 0.1 12.4 0.4 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KKK23753.1 - 0.13 12.5 0.4 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KKK23753.1 - 0.13 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ras PF00071.17 KKK23754.1 - 1.1e-63 213.4 0.2 1.3e-63 213.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK23754.1 - 1.8e-21 76.8 0.1 2.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK23754.1 - 2.5e-13 49.6 0.1 3.3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KKK23754.1 - 5.1e-08 32.8 0.1 8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KKK23754.1 - 5.9e-05 22.3 0.1 0.00011 21.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KKK23754.1 - 6.4e-05 22.4 0.1 0.00023 20.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KKK23754.1 - 0.00012 22.1 0.0 0.00037 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KKK23754.1 - 0.00087 18.4 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KKK23754.1 - 0.0012 18.7 0.1 0.0032 17.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KKK23754.1 - 0.0027 16.9 0.1 0.0056 15.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 KKK23754.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KKK23754.1 - 0.018 15.3 0.2 0.023 14.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KKK23754.1 - 0.018 15.0 0.3 0.04 13.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 KKK23754.1 - 0.025 14.1 0.1 0.049 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF4468 PF14730.1 KKK23754.1 - 0.056 13.1 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold SpoIIID PF12116.3 KKK23754.1 - 0.072 13.0 0.1 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.13 KKK23754.1 - 0.081 12.2 0.1 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 KKK23754.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KKK23754.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF221 PF02714.10 KKK23755.1 - 8.4e-99 330.4 18.9 1.5e-98 329.6 13.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KKK23755.1 - 1.2e-44 151.6 1.2 1.2e-44 151.6 0.8 2.8 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KKK23755.1 - 1.3e-24 86.4 0.5 2.6e-24 85.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 KKK23755.1 - 0.00023 21.0 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) hDGE_amylase PF14701.1 KKK23756.1 - 1.3e-177 590.9 0.1 1.7e-177 590.5 0.1 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KKK23756.1 - 1.1e-110 369.9 0.1 2.5e-110 368.6 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KKK23756.1 - 5.4e-88 294.5 0.0 8.2e-88 293.9 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KKK23756.1 - 1.4e-27 95.3 0.0 3.2e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KKK23756.1 - 0.00021 20.7 0.1 0.05 12.9 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KKK23757.1 - 1.9e-47 160.8 0.0 3.2e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KKK23757.1 - 3.3e-43 146.9 0.2 4.8e-43 146.4 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 KKK23757.1 - 0.073 13.5 0.0 14 6.1 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PfkB PF00294.19 KKK23758.1 - 2.2e-18 66.4 0.0 4.1e-18 65.5 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase CVNH PF08881.5 KKK23760.1 - 5.9e-29 100.3 0.2 6.5e-29 100.2 0.1 1.0 1 0 0 1 1 1 1 CVNH domain ETX_MTX2 PF03318.8 KKK23760.1 - 0.044 13.3 0.1 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF4597 PF15366.1 KKK23761.1 - 1.4 8.5 4.7 13 5.4 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4597) YscJ_FliF PF01514.12 KKK23762.1 - 0.034 13.2 0.1 0.068 12.3 0.0 1.4 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family DUF2744 PF10910.3 KKK23764.1 - 0.073 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) F-box-like PF12937.2 KKK23765.1 - 0.0024 17.5 0.8 0.0058 16.3 0.5 1.7 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 KKK23765.1 - 1.9 8.8 7.3 0.74 10.0 1.2 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 KKK23765.1 - 9.4 6.9 8.7 2.4 8.7 0.6 4.2 5 0 0 5 5 5 0 Leucine rich repeat Abp2 PF09441.5 KKK23766.1 - 3.8e-88 293.9 0.1 5.6e-88 293.4 0.1 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Surfac_D-trimer PF09006.6 KKK23766.1 - 0.22 11.2 2.0 0.45 10.2 1.4 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation TrkA_N PF02254.13 KKK23771.1 - 0.22 11.5 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF3844 PF12955.2 KKK23772.1 - 4.2e-38 129.5 2.9 6.8e-38 128.9 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Ceramidase_alk PF04734.8 KKK23772.1 - 0.094 10.5 2.5 0.13 10.0 1.7 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase CKS PF01111.14 KKK23773.1 - 8.8e-37 124.7 0.3 1.2e-36 124.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 KKK23773.1 - 0.11 12.4 0.5 0.34 10.9 0.1 2.1 2 0 0 2 2 2 0 APC 15 residue motif Thioredoxin_4 PF13462.1 KKK23774.1 - 8.1e-07 29.1 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KKK23774.1 - 0.1 12.1 1.3 3.9 6.9 0.1 2.3 1 1 0 2 2 2 0 DSBA-like thioredoxin domain APC_CDC26 PF10471.4 KKK23775.1 - 3.2e-17 63.0 0.5 3.7e-17 62.8 0.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Pinin_SDK_N PF04697.8 KKK23776.1 - 0.0034 17.4 2.1 0.0067 16.4 1.5 1.4 1 0 0 1 1 1 1 pinin/SDK conserved region Aldedh PF00171.17 KKK23777.1 - 5.7e-157 522.7 0.0 6.6e-157 522.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 KKK23778.1 - 1.2e-49 169.0 0.0 1.6e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK23778.1 - 1.5e-40 138.7 0.0 2.4e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK23778.1 - 1.8e-06 27.0 0.0 0.038 12.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK23778.1 - 3.4e-06 26.2 0.5 0.00057 18.8 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK23778.1 - 0.00035 20.5 0.1 0.00093 19.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK23778.1 - 0.00064 18.7 0.0 0.00094 18.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KKK23778.1 - 0.0036 16.4 0.2 0.045 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK23778.1 - 0.0073 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KKK23778.1 - 0.025 13.2 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF59 PF01883.14 KKK23779.1 - 2.7e-06 27.2 0.1 5.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 Pheromone PF08015.6 KKK23779.1 - 0.53 11.1 3.5 4.6 8.1 0.0 2.7 3 0 0 3 3 3 0 Fungal mating-type pheromone Fungal_trans PF04082.13 KKK23780.1 - 2.9e-09 36.1 0.2 5.4e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23780.1 - 4.9e-07 29.5 8.1 9.3e-07 28.6 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRF PF01765.14 KKK23781.1 - 4.7e-20 71.6 0.1 7.9e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 Ribosome recycling factor HSP70 PF00012.15 KKK23782.1 - 4.4e-231 768.0 8.3 4.9e-231 767.8 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KKK23782.1 - 1.1e-16 60.3 0.1 1.2e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KKK23782.1 - 0.00073 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 KKK23782.1 - 0.012 14.4 0.2 0.16 10.8 0.0 2.4 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain MRC1 PF09444.5 KKK23782.1 - 0.023 15.0 1.7 0.066 13.5 1.2 1.7 1 0 0 1 1 1 0 MRC1-like domain Glyco_hydro_3 PF00933.16 KKK23783.1 - 4.6e-57 193.2 0.0 6.9e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK23783.1 - 7.3e-05 22.3 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 KKK23783.1 - 0.00013 21.8 0.0 0.0005 20.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK23783.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KKK23783.1 - 0.074 13.0 0.2 0.53 10.2 0.1 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Glucosamine_iso PF01182.15 KKK23784.1 - 2.2e-23 83.0 0.0 3.7e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.8 KKK23784.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain CPSF_A PF03178.10 KKK23785.1 - 3.9e-106 354.7 0.0 2.2e-105 352.3 0.0 2.2 3 0 0 3 3 3 1 CPSF A subunit region NDT80_PhoG PF05224.7 KKK23786.1 - 2.5e-37 128.7 0.6 9.3e-37 126.8 0.4 2.0 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Macoilin PF09726.4 KKK23786.1 - 0.39 8.9 2.0 0.53 8.4 1.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_LMP2 PF07415.6 KKK23786.1 - 0.96 7.9 3.0 1.3 7.4 2.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Pex14_N PF04695.8 KKK23786.1 - 3.3 7.7 11.1 0.51 10.3 4.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATP_Ca_trans_C PF12424.3 KKK23787.1 - 0.067 13.5 0.3 1.3 9.4 0.0 2.4 1 1 1 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal LMBR1 PF04791.11 KKK23788.1 - 4.6e-14 51.8 6.7 4.6e-14 51.8 4.6 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF2040 PF09745.4 KKK23788.1 - 0.012 15.4 0.6 0.026 14.3 0.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) Zip PF02535.17 KKK23789.1 - 3.4e-32 111.7 0.6 4.5e-32 111.3 0.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Atg14 PF10186.4 KKK23790.1 - 1.3e-77 260.6 0.2 1.6e-77 260.4 0.2 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 GTP_EFTU PF00009.22 KKK23791.1 - 7.6e-43 146.1 0.0 1.1e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KKK23791.1 - 3e-27 94.5 0.0 8.6e-27 93.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KKK23791.1 - 4.6e-19 68.0 0.0 1.1e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KKK23791.1 - 1.6e-10 40.9 0.0 4.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KKK23791.1 - 4.2e-07 29.7 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KKK23791.1 - 5.6e-05 23.0 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK23791.1 - 0.0026 18.2 0.1 0.0073 16.7 0.1 1.8 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KKK23791.1 - 0.049 12.8 0.1 0.35 10.0 0.1 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.17 KKK23791.1 - 0.15 11.4 0.0 0.64 9.3 0.0 2.0 1 1 0 1 1 1 0 Ras family Tox-PL PF15644.1 KKK23791.1 - 0.23 12.2 0.0 0.9 10.3 0.0 1.9 2 0 0 2 2 2 0 Papain fold toxin 1 Thiolase_N PF00108.18 KKK23792.1 - 1.2e-97 326.0 0.0 2.1e-97 325.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK23792.1 - 7.3e-45 151.3 3.4 1.1e-44 150.7 1.8 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KKK23792.1 - 2.2e-05 24.1 2.7 2.9e-05 23.6 1.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KKK23792.1 - 0.032 13.8 2.1 0.75 9.5 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III tRNA-synt_2c PF01411.14 KKK23794.1 - 6.7e-216 717.8 0.1 1e-215 717.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KKK23794.1 - 6.7e-17 61.1 0.4 1.6e-16 59.8 0.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KKK23794.1 - 0.0015 18.1 0.2 0.0038 16.8 0.1 1.8 1 0 0 1 1 1 1 DHHA1 domain Pro_isomerase PF00160.16 KKK23795.1 - 2.7e-49 167.3 0.6 3.1e-49 167.1 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.1 KKK23796.1 - 1e-14 54.0 2.9 1.6e-14 53.3 2.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK23796.1 - 1.3e-08 34.3 0.9 2.1e-08 33.6 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK23796.1 - 4.8e-08 33.0 2.5 1.1e-07 31.8 1.7 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KKK23796.1 - 9.1e-08 32.0 2.1 1.5e-07 31.3 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK23796.1 - 4.3e-07 29.5 0.9 6.6e-07 28.9 0.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK23796.1 - 6.8e-06 25.6 0.4 1e-05 25.0 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KKK23796.1 - 0.00021 21.0 1.4 0.00066 19.4 1.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KKK23796.1 - 0.0011 18.7 1.7 0.0032 17.3 1.2 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KKK23796.1 - 0.0029 17.1 2.8 0.0048 16.4 1.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.24 KKK23796.1 - 0.0071 16.0 2.2 0.012 15.3 1.5 1.4 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.2 KKK23796.1 - 0.026 14.5 2.3 0.049 13.6 1.6 1.5 1 0 0 1 1 1 0 RING-variant domain DUF605 PF04652.11 KKK23796.1 - 0.041 13.2 5.4 0.022 14.1 2.4 1.5 1 1 0 1 1 1 0 Vta1 like FANCL_C PF11793.3 KKK23796.1 - 0.2 11.6 3.0 0.6 10.1 2.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KKK23796.1 - 0.2 11.3 0.9 0.57 9.9 0.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 KKK23796.1 - 0.22 11.5 2.5 0.36 10.8 1.7 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 KKK23796.1 - 0.72 9.6 5.1 5.3 6.8 3.5 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DUF3517 PF12030.3 KKK23828.1 - 8.6e-174 576.8 0.1 2.1e-173 575.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 KKK23828.1 - 2e-47 161.5 0.5 3.3e-47 160.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK23828.1 - 8e-17 61.6 1.5 1.4e-16 60.7 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PCI PF01399.22 KKK23841.1 - 1.2e-20 73.7 0.7 2.7e-20 72.6 0.1 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KKK23841.1 - 8.4e-07 28.8 0.1 1.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 KKK23841.1 - 0.0015 18.1 0.8 0.55 10.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK23841.1 - 0.0015 18.2 2.3 0.17 11.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 KKK23841.1 - 0.0036 17.1 0.3 0.98 9.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK23841.1 - 0.0042 16.6 0.9 0.38 10.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Ipi1_N PF12333.3 KKK23841.1 - 0.012 15.6 0.1 0.23 11.4 0.0 2.5 2 1 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_12 PF13424.1 KKK23841.1 - 0.016 15.1 1.9 0.35 10.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK23841.1 - 0.038 13.7 2.5 0.67 9.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KKK23841.1 - 0.51 10.0 3.0 1.5 8.5 0.1 3.2 3 2 1 4 4 4 0 TPR repeat Ras PF00071.17 KKK23842.1 - 7.3e-43 145.7 0.3 3.4e-42 143.5 0.2 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK23842.1 - 1.3e-11 44.9 0.0 2.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK23842.1 - 4.1e-05 22.8 0.2 0.00028 20.1 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK23842.1 - 0.0036 16.4 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region BPL_LplA_LipB PF03099.14 KKK23843.1 - 4.3e-08 33.2 0.0 8.1e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Acetyltransf_10 PF13673.1 KKK23845.1 - 9e-06 25.8 1.2 1.7e-05 24.9 0.2 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK23845.1 - 0.0003 20.7 0.4 0.00068 19.6 0.3 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KKK23845.1 - 0.0062 16.3 0.2 0.019 14.8 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK23845.1 - 0.022 14.8 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KKK23845.1 - 0.96 9.0 4.1 5.6 6.5 2.9 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain B12D PF06522.6 KKK23845.1 - 2.8 7.6 4.9 0.85 9.3 0.2 2.2 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DAO PF01266.19 KKK23846.1 - 3.2e-23 82.2 1.5 1.3e-22 80.1 1.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK23846.1 - 5.8e-06 26.6 0.0 0.00016 22.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK23846.1 - 2.3e-05 24.3 0.1 5.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KKK23846.1 - 0.00022 21.4 0.0 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 KKK23846.1 - 0.00056 19.8 0.0 0.0073 16.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK23846.1 - 0.0011 17.8 0.1 0.0025 16.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 KKK23846.1 - 0.0045 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KKK23846.1 - 0.0055 16.1 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KKK23846.1 - 0.0077 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KKK23846.1 - 0.033 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 KKK23846.1 - 0.04 13.9 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KKK23846.1 - 0.048 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 KKK23846.1 - 0.054 13.5 0.0 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding GIDA PF01134.17 KKK23846.1 - 0.088 11.6 0.1 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 KKK23846.1 - 0.17 11.6 0.2 2.7 7.7 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KKK23846.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KKK23847.1 - 1.8e-05 24.0 0.0 3.2e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK23847.1 - 6.7e-05 21.9 0.0 0.00016 20.7 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK23847.1 - 7.5e-05 22.6 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KKK23847.1 - 0.0002 20.1 0.0 0.0017 17.0 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 KKK23847.1 - 0.0013 18.4 0.1 0.0044 16.7 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK23847.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK23847.1 - 0.027 13.3 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KKK23847.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 KKK23847.1 - 0.79 8.5 2.2 1.3 7.8 1.5 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KKK23848.1 - 0.00048 19.2 0.0 0.00056 19.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pec_lyase_C PF00544.14 KKK23849.1 - 7.6e-48 162.6 7.4 1.1e-47 162.1 5.1 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KKK23849.1 - 1.4e-06 28.1 8.8 4.7e-06 26.4 5.9 1.9 1 1 0 1 1 1 1 Right handed beta helix region Glyco_hydro_18 PF00704.23 KKK23850.1 - 3e-13 49.9 0.0 5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TPR_11 PF13414.1 KKK23851.1 - 2e-05 24.1 0.1 5.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 TPR repeat UBA PF00627.26 KKK23851.1 - 0.00056 19.6 0.1 0.0019 17.9 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.26 KKK23851.1 - 0.0097 15.6 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.1 KKK23851.1 - 0.024 15.2 2.1 0.024 15.2 1.5 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat TetR_C PF02909.12 KKK23851.1 - 0.027 14.1 0.0 0.095 12.3 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain TPR_2 PF07719.12 KKK23851.1 - 0.092 12.7 5.3 0.031 14.1 0.8 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat GCD14 PF08704.5 KKK23852.1 - 1.5e-53 181.7 0.0 3.4e-53 180.6 0.0 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit tRNA-synt_1e PF01406.14 KKK23853.1 - 3e-115 384.4 0.0 4.9e-115 383.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KKK23853.1 - 2.4e-06 26.4 1.2 0.024 13.2 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) NMO PF03060.10 KKK23854.1 - 1.8e-60 204.8 0.5 5.8e-39 134.1 0.1 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KKK23854.1 - 1.7e-11 43.6 0.0 6.4e-05 22.0 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KKK23854.1 - 0.0064 15.3 0.4 0.012 14.4 0.3 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KKK23854.1 - 0.043 12.7 0.5 0.11 11.4 0.2 1.7 1 1 1 2 2 2 0 Conserved region in glutamate synthase Hydrophobin PF01185.13 KKK23855.1 - 2.8e-15 56.4 7.6 3.8e-15 56.1 5.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF1688 PF07958.6 KKK23856.1 - 1.4e-177 590.5 0.0 1.5e-177 590.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.7 KKK23857.1 - 1.2e-92 309.2 0.2 1.5e-92 308.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KKK23857.1 - 4.4e-08 32.5 0.0 6.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KKK23857.1 - 5.4e-08 32.3 0.0 8.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK23857.1 - 6.4e-06 26.6 0.0 1.4e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK23857.1 - 8.8e-06 25.6 0.0 3.7e-05 23.6 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK23857.1 - 0.00064 19.1 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KKK23857.1 - 0.0013 18.1 0.3 0.0051 16.3 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 KKK23857.1 - 0.0092 14.9 0.1 0.02 13.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 KKK23857.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KKK23857.1 - 0.069 12.3 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AIG1 PF04548.11 KKK23857.1 - 0.11 11.5 0.2 0.39 9.7 0.0 2.0 2 0 0 2 2 2 0 AIG1 family AAA_10 PF12846.2 KKK23857.1 - 0.15 11.4 0.3 0.3 10.4 0.2 1.6 1 1 0 1 1 1 0 AAA-like domain G-alpha PF00503.15 KKK23857.1 - 0.19 10.3 2.6 3.3 6.3 0.7 2.2 1 1 1 2 2 2 0 G-protein alpha subunit QCR10 PF09796.4 KKK23858.1 - 9.6e-30 102.0 0.4 1.3e-29 101.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) ETC_C1_NDUFA5 PF04716.9 KKK23859.1 - 8.2e-23 79.6 0.1 8.2e-23 79.6 0.1 2.8 3 0 0 3 3 3 1 ETC complex I subunit conserved region Trypan_PARP PF05887.6 KKK23859.1 - 0.11 12.3 4.0 0.18 11.5 2.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Thioredoxin PF00085.15 KKK23860.1 - 5.1e-47 157.8 0.1 4e-25 87.5 0.0 4.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KKK23860.1 - 1.5e-12 47.6 0.0 0.0018 18.1 0.0 5.1 3 1 2 5 5 5 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KKK23860.1 - 3.4e-10 40.0 0.4 0.029 14.5 0.1 4.4 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KKK23860.1 - 3.5e-07 30.2 0.1 0.003 17.6 0.0 4.1 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KKK23860.1 - 0.00065 19.6 2.2 0.0052 16.7 0.2 2.9 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KKK23860.1 - 0.0013 18.5 0.1 0.28 11.0 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin domain HyaE PF07449.6 KKK23860.1 - 0.0013 18.6 0.0 1.1 9.2 0.0 3.2 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 KKK23860.1 - 0.0073 15.9 0.7 0.18 11.4 0.1 3.2 4 0 0 4 4 4 1 AhpC/TSA family GDYXXLXY PF14345.1 KKK23860.1 - 0.036 13.9 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 GDYXXLXY protein Prophage_tail PF06605.6 KKK23860.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Prophage endopeptidase tail Coatomer_WDAD PF04053.9 KKK23861.1 - 3.5e-158 527.0 0.0 1.3e-155 518.5 0.0 2.7 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 KKK23861.1 - 1.3e-46 154.8 12.1 5.1e-10 38.8 0.1 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 KKK23861.1 - 0.00046 18.4 3.5 0.066 11.3 0.1 4.2 2 2 1 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KKK23861.1 - 0.0027 17.4 0.0 1.9 8.2 0.0 3.3 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region SWIRM PF04433.12 KKK23863.1 - 4.6e-17 61.9 0.0 1.5e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 KKK23863.1 - 7.1e-12 44.6 6.0 1.1e-11 44.0 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KKK23863.1 - 3.1e-08 33.5 0.0 7.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Asp PF00026.18 KKK23865.1 - 2e-96 322.9 0.2 1.8e-93 313.2 0.1 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK23865.1 - 5.3e-12 46.0 0.1 1.6e-11 44.4 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KKK23865.1 - 1.3e-06 28.7 0.1 0.043 14.3 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KKK23865.1 - 4.7e-06 26.2 0.0 2.5e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal MARVEL PF01284.18 KKK23866.1 - 0.00084 19.1 9.6 0.001 18.8 6.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain NIF PF03031.13 KKK23867.1 - 2e-26 92.5 0.0 4.7e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KKK23867.1 - 4.7e-09 35.9 0.2 9.3e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KKK23867.1 - 7e-08 32.5 0.0 2.2e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KKK23868.1 - 1.8e-46 157.6 0.6 5.6e-46 156.0 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK23868.1 - 3.5e-09 36.5 0.5 1.2e-08 34.8 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KKK23868.1 - 8e-09 35.6 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KKK23868.1 - 1.6e-07 31.5 0.0 5.4e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK23868.1 - 7.1e-07 29.4 0.7 0.0001 22.4 0.5 2.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK23868.1 - 1.4e-05 24.9 0.0 6.7e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KKK23868.1 - 5.9e-05 22.1 0.0 0.00012 21.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KKK23868.1 - 0.00026 21.7 0.0 0.0014 19.4 0.0 2.1 3 0 0 3 3 1 1 AAA domain RuvB_N PF05496.7 KKK23868.1 - 0.00042 19.4 0.0 0.00098 18.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KKK23868.1 - 0.00062 19.4 0.9 0.056 13.0 0.0 3.1 3 1 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 KKK23868.1 - 0.00063 18.8 0.1 0.002 17.2 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 KKK23868.1 - 0.0007 19.3 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 NTPase UPF0079 PF02367.12 KKK23868.1 - 0.0009 18.8 0.1 0.038 13.6 0.0 2.3 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 KKK23868.1 - 0.0012 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KKK23868.1 - 0.0012 18.4 0.1 0.0033 17.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KKK23868.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KKK23868.1 - 0.0023 17.8 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK23868.1 - 0.0031 17.1 0.4 0.012 15.2 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_3 PF07726.6 KKK23868.1 - 0.0033 17.0 0.0 0.0093 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KKK23868.1 - 0.0042 16.5 0.6 0.049 13.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KKK23868.1 - 0.0051 16.3 0.0 0.23 10.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_23 PF13476.1 KKK23868.1 - 0.0054 17.0 0.2 0.54 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KKK23868.1 - 0.0055 15.4 0.0 0.0097 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KKK23868.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KKK23868.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KKK23868.1 - 0.0091 15.7 0.8 0.15 11.6 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 KKK23868.1 - 0.013 14.9 0.3 0.033 13.6 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 KKK23868.1 - 0.02 14.4 0.1 0.083 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 KKK23868.1 - 0.027 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 KKK23868.1 - 0.03 14.6 0.0 0.097 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KKK23868.1 - 0.064 13.3 0.0 0.36 10.8 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 KKK23868.1 - 0.099 11.7 0.8 0.47 9.5 0.0 2.3 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.22 KKK23868.1 - 0.12 12.6 0.1 0.46 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Viral_Hsp90 PF03225.9 KKK23868.1 - 0.13 10.5 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.12 KKK23868.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 F-box-like PF12937.2 KKK23869.1 - 1.6e-13 50.1 0.6 1.6e-13 50.1 0.4 2.4 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.1 KKK23869.1 - 8.8e-12 44.6 12.9 0.11 12.3 1.0 6.8 3 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KKK23869.1 - 2.3e-11 43.0 4.6 0.29 10.7 0.0 7.4 5 3 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KKK23869.1 - 1.2e-10 40.2 6.7 3.4 8.0 0.1 10.7 12 0 0 12 12 12 1 Leucine Rich repeat F-box PF00646.28 KKK23869.1 - 4e-05 23.1 0.2 4e-05 23.1 0.1 2.5 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.28 KKK23869.1 - 0.01 15.7 24.4 39 4.8 0.0 10.1 8 4 0 8 8 8 0 Leucine Rich Repeat DUF1699 PF08004.6 KKK23869.1 - 0.047 13.2 2.0 0.45 10.0 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1699) Peptidase_M28 PF04389.12 KKK23870.1 - 1.9e-32 112.4 0.0 3.8e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.15 KKK23870.1 - 0.0049 17.0 0.8 0.0049 17.0 0.5 5.0 7 0 0 7 7 5 1 ATP synthase protein 8 PBP1_TM PF14812.1 KKK23870.1 - 0.019 15.2 2.6 0.07 13.4 1.8 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M20 PF01546.23 KKK23870.1 - 0.031 13.7 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 DUF2457 PF10446.4 KKK23870.1 - 0.18 10.4 7.2 0.32 9.6 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 KKK23870.1 - 0.27 11.4 9.2 0.61 10.3 6.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.9 KKK23870.1 - 0.34 10.4 0.7 0.57 9.6 0.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prothymosin PF03247.9 KKK23870.1 - 0.5 10.5 15.2 1.2 9.3 10.5 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nucleoplasmin PF03066.10 KKK23870.1 - 4.8 6.6 11.8 9.5 5.7 7.7 1.7 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 KKK23870.1 - 6.8 6.2 6.9 12 5.4 4.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 KKK23870.1 - 7.4 4.3 7.9 11 3.7 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family TauD PF02668.11 KKK23872.1 - 3.1e-15 56.5 0.7 2.7e-09 37.0 0.3 2.2 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KKK23872.1 - 0.11 11.4 0.3 0.19 10.6 0.2 1.3 1 0 0 1 1 1 0 CsiD Zn_clus PF00172.13 KKK23873.1 - 5.2 7.0 12.2 0.67 9.9 5.3 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KKK23875.1 - 8.2e-37 126.7 0.0 1.2e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23875.1 - 2e-27 95.9 0.0 2.8e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK23875.1 - 0.084 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Med10 PF09748.4 KKK23876.1 - 1.1e-40 138.4 0.4 1e-39 135.2 0.3 1.9 1 1 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 KKK23876.1 - 0.048 13.2 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Amidase PF01425.16 KKK23877.1 - 1.1e-79 268.3 0.0 1.3e-79 268.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Pkinase PF00069.20 KKK23878.1 - 1.8e-09 37.1 0.0 6.7e-09 35.2 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23878.1 - 1.7e-08 33.8 0.0 1.1e-07 31.1 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KKK23878.1 - 0.039 13.0 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CN_hydrolase PF00795.17 KKK23879.1 - 5.9e-31 107.2 0.1 7.9e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Mpv17_PMP22 PF04117.7 KKK23880.1 - 2.4e-22 78.3 0.1 2.4e-22 78.3 0.1 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Trs65 PF12735.2 KKK23881.1 - 1.9e-70 237.5 0.0 2.6e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.14 KKK23882.1 - 1.9e-59 197.3 17.0 3.9e-15 55.5 0.3 7.2 6 1 0 6 6 6 6 FF domain WW PF00397.21 KKK23882.1 - 2.3e-18 65.7 9.0 1.1e-08 34.8 2.7 2.7 2 0 0 2 2 2 2 WW domain DUF3808 PF10300.4 KKK23883.1 - 2.1e-156 521.1 0.3 3.2e-156 520.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DehI PF10778.4 KKK23883.1 - 0.018 14.5 0.0 0.051 13.0 0.0 1.8 1 1 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI DSS1_SEM1 PF05160.8 KKK23884.1 - 6.9e-26 89.8 15.5 1e-25 89.2 10.7 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family DUF4106 PF13388.1 KKK23884.1 - 0.038 12.9 2.9 0.039 12.9 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PGK PF00162.14 KKK23885.1 - 6.1e-138 459.5 3.9 3.7e-136 453.6 2.7 2.0 1 1 0 1 1 1 1 Phosphoglycerate kinase SBP_bac_8 PF13416.1 KKK23885.1 - 0.015 15.0 1.3 0.029 14.0 0.5 1.7 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein TPT PF03151.11 KKK23886.1 - 3e-25 88.6 11.2 3e-25 88.6 7.8 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KKK23886.1 - 3.3e-08 32.8 21.4 1.3e-07 30.8 14.9 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KKK23886.1 - 0.0018 18.3 30.8 0.0021 18.0 7.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family MARVEL PF01284.18 KKK23887.1 - 4.8e-31 107.5 11.9 5.5e-31 107.3 8.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain Gly_transf_sug PF04488.10 KKK23888.1 - 1.7e-12 47.5 0.1 2.8e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TOM_sub5 PF15178.1 KKK23888.1 - 0.1 12.3 0.4 4.2 7.1 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial import receptor subunit TOM5 homolog TcdA_TcdB PF12919.2 KKK23888.1 - 4.3 5.6 4.6 4.8 5.5 0.5 2.4 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain AMP-binding_C PF13193.1 KKK23901.1 - 4.5e-13 49.9 0.2 5.8e-13 49.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 KKK23902.1 - 2.4e-45 154.8 42.4 2.4e-45 154.8 29.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK23902.1 - 2.9e-10 39.3 26.8 6.5e-10 38.1 18.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KKK23902.1 - 3.6e-06 25.4 4.1 5.8e-06 24.7 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KKK23902.1 - 0.00023 19.3 7.7 0.25 9.3 0.6 3.8 4 0 0 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family DUF3712 PF12505.3 KKK23903.1 - 2.2e-29 102.0 0.2 7.5e-29 100.3 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) YlbD_coat PF14071.1 KKK23903.1 - 3.5 7.7 6.1 19 5.3 0.1 4.0 2 2 1 3 3 3 0 Putative coat protein 5_nucleotid PF05761.9 KKK23904.1 - 0.18 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family Zn_clus PF00172.13 KKK23905.1 - 2.4e-08 33.7 10.6 6.2e-08 32.4 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KKK23905.1 - 0.0027 17.9 3.3 0.013 15.8 2.3 2.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK23905.1 - 0.0063 16.7 2.0 0.0063 16.7 1.4 2.6 3 0 0 3 3 3 1 C2H2-type zinc finger Condensation PF00668.15 KKK23906.1 - 1e-05 24.5 0.2 0.00012 21.0 0.1 2.2 1 1 0 1 1 1 1 Condensation domain ParG PF09274.5 KKK23906.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 ParG Metallophos_2 PF12850.2 KKK23907.1 - 0.075 12.8 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RTA1 PF04479.8 KKK23908.1 - 1.2e-43 149.1 3.5 1.5e-43 148.8 2.5 1.0 1 0 0 1 1 1 1 RTA1 like protein Ank_2 PF12796.2 KKK23909.1 - 7.5e-50 167.2 4.6 4.7e-18 65.2 0.1 8.1 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KKK23909.1 - 3.7e-35 117.9 13.7 5e-06 26.0 0.0 11.7 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.1 KKK23909.1 - 2e-34 116.8 13.9 1.3e-05 25.2 0.1 10.8 10 1 1 11 11 11 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK23909.1 - 3.2e-33 113.5 13.8 3e-08 33.9 0.0 10.6 8 2 2 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK23909.1 - 1.3e-32 108.5 6.6 0.001 19.0 0.0 12.2 13 0 0 13 13 13 5 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.1 KKK23910.1 - 7.8e-07 29.5 0.1 1.5e-06 28.6 0.1 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KKK23910.1 - 0.00088 18.8 0.1 0.0017 17.9 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PLA2_B PF01735.13 KKK23911.1 - 3.8e-200 665.2 2.1 4.6e-200 664.9 1.5 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MMS19_C PF12460.3 KKK23913.1 - 2.5e-17 62.7 1.2 3.6e-17 62.1 0.8 1.2 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 KKK23913.1 - 5.2e-05 23.4 1.1 0.044 14.0 0.1 2.4 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.17 KKK23913.1 - 0.00088 19.1 4.1 0.24 11.6 0.1 2.9 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 KKK23913.1 - 0.00099 19.5 5.9 1 9.9 0.3 3.7 3 1 0 3 3 3 2 HEAT-like repeat CAF1A PF12253.3 KKK23915.1 - 3.3e-25 87.9 6.1 3.3e-25 87.9 4.2 3.4 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KKK23915.1 - 3.1e-08 33.2 77.9 4.8e-08 32.6 51.7 2.4 1 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIF_alpha PF05793.7 KKK23915.1 - 0.0004 18.8 26.4 0.0004 18.8 18.3 2.3 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Raftlin PF15250.1 KKK23915.1 - 0.096 11.1 12.3 0.17 10.3 7.5 1.9 2 0 0 2 2 2 0 Raftlin LMBR1 PF04791.11 KKK23915.1 - 2.5 6.5 7.6 3.3 6.1 5.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.10 KKK23915.1 - 3.8 6.0 15.2 1.9 7.0 9.0 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Macoilin PF09726.4 KKK23915.1 - 4.1 5.5 23.9 6.8 4.8 16.6 1.3 1 0 0 1 1 1 0 Transmembrane protein Fungal_trans_2 PF11951.3 KKK23916.1 - 6.2e-87 291.6 0.0 7.9e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23916.1 - 1.1e-05 25.1 11.2 2e-05 24.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M48 PF01435.13 KKK23917.1 - 8.5e-35 120.3 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Cpn60_TCP1 PF00118.19 KKK23918.1 - 9.5e-132 440.0 4.9 2e-123 412.5 2.8 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family DUF2052 PF09747.4 KKK23918.1 - 0.0018 18.2 1.4 0.0033 17.3 1.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Ribosomal_60s PF00428.14 KKK23918.1 - 0.031 14.6 10.0 0.12 12.7 6.9 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.13 KKK23918.1 - 0.18 10.9 6.6 0.28 10.2 4.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CobT PF06213.7 KKK23918.1 - 0.2 10.7 11.7 0.066 12.3 6.1 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 KKK23918.1 - 0.22 10.5 6.3 0.35 9.8 4.4 1.2 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.6 KKK23918.1 - 0.71 9.6 4.5 1.5 8.5 3.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 KKK23918.1 - 0.94 7.8 9.9 1.4 7.3 6.9 1.1 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 KKK23918.1 - 1.1 7.9 6.3 1.6 7.3 4.4 1.2 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.7 KKK23918.1 - 1.1 8.4 6.8 1.6 7.8 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 KKK23918.1 - 1.9 7.4 6.8 3.3 6.6 4.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 KKK23918.1 - 3.9 5.2 12.1 6.3 4.5 8.4 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 KKK23918.1 - 5.5 6.5 13.3 2 7.9 7.1 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KKK23918.1 - 9.8 5.6 13.4 21 4.6 9.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin Polysacc_deac_1 PF01522.16 KKK23919.1 - 1.6e-20 72.9 0.0 3.1e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KKK23919.1 - 1.9e-07 30.3 0.0 4.2e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Creatininase PF02633.9 KKK23919.1 - 6.5e-06 25.3 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Creatinine amidohydrolase TP_methylase PF00590.15 KKK23919.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Nitroreductase PF00881.19 KKK23920.1 - 5.9e-15 55.4 0.0 7.2e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Ins_P5_2-kin PF06090.7 KKK23921.1 - 3.6e-75 252.8 0.0 4.2e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF77 PF01910.12 KKK23922.1 - 8.3e-12 44.6 0.1 3e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function DUF77 DUF2749 PF10907.3 KKK23923.1 - 0.19 11.5 0.5 0.42 10.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) AAA PF00004.24 KKK23925.1 - 3.3e-38 130.8 0.0 1.2e-37 129.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KKK23925.1 - 5.1e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KKK23925.1 - 3.1e-05 24.1 0.1 0.00071 19.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK23925.1 - 3.1e-05 24.7 0.0 0.00012 22.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK23925.1 - 4.5e-05 23.5 0.2 0.00058 19.8 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KKK23925.1 - 5.3e-05 22.3 0.0 9.1e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KKK23925.1 - 6.6e-05 22.6 0.1 0.00053 19.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KKK23925.1 - 0.00018 21.4 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KKK23925.1 - 0.00019 20.8 0.0 0.00046 19.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KKK23925.1 - 0.00031 20.6 0.0 0.00074 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KKK23925.1 - 0.00056 19.3 0.2 0.035 13.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KKK23925.1 - 0.0011 18.2 0.1 0.0021 17.2 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 KKK23925.1 - 0.0013 18.7 0.0 0.0041 17.1 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 KKK23925.1 - 0.0016 18.5 0.0 0.0043 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 KKK23925.1 - 0.004 16.8 0.0 0.013 15.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 KKK23925.1 - 0.0047 16.8 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK23925.1 - 0.0071 15.4 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KKK23925.1 - 0.0077 16.5 0.0 0.022 15.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 KKK23925.1 - 0.0081 15.7 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK23925.1 - 0.0089 15.7 0.4 0.036 13.8 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain Parvo_NS1 PF01057.12 KKK23925.1 - 0.022 13.6 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 KKK23925.1 - 0.033 14.4 0.0 0.09 13.0 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 KKK23925.1 - 0.038 13.4 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 KKK23925.1 - 0.06 12.2 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.7 KKK23925.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 KKK23925.1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase Rad17 PF03215.10 KKK23925.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 KKK23925.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 KKK23925.1 - 0.13 11.1 0.0 0.27 10.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 KKK23925.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 KKK23925.1 - 0.16 10.6 0.1 0.35 9.5 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus PigN PF04987.9 KKK23926.1 - 2.8e-174 579.9 37.3 3.8e-174 579.4 25.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Csm1 PF12539.3 KKK23926.1 - 7.8e-28 96.7 1.2 1.3e-27 96.0 0.1 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Phosphodiest PF01663.17 KKK23926.1 - 4.7e-10 39.3 0.4 4.2e-08 32.9 0.0 2.4 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KKK23926.1 - 1.7e-08 33.9 0.0 2.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF2968 PF11180.3 KKK23926.1 - 0.017 14.4 10.1 0.034 13.5 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HAUS-augmin3 PF14932.1 KKK23926.1 - 0.12 11.5 9.3 0.19 10.8 6.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 AAA_13 PF13166.1 KKK23926.1 - 0.36 9.2 6.2 0.67 8.3 4.3 1.4 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 KKK23926.1 - 0.37 9.7 9.6 0.62 9.0 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 KKK23926.1 - 0.41 7.9 11.5 0.58 7.4 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin_2 PF14523.1 KKK23926.1 - 0.42 10.6 5.5 0.98 9.4 3.8 1.6 1 0 0 1 1 1 0 Syntaxin-like protein Spc7 PF08317.6 KKK23926.1 - 0.42 9.2 9.3 0.69 8.5 6.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein NYD-SP28 PF14772.1 KKK23926.1 - 0.53 10.4 4.4 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Sperm tail DUF3138 PF11336.3 KKK23926.1 - 1.5 6.9 6.5 2.4 6.2 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TMF_DNA_bd PF12329.3 KKK23926.1 - 5.6 6.8 13.7 0.92 9.3 3.9 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 KKK23926.1 - 5.7 6.8 14.2 29 4.5 9.9 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fungal_trans PF04082.13 KKK23927.1 - 3.4e-33 114.6 0.0 2.3e-32 111.8 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23927.1 - 0.0017 18.1 1.2 0.0033 17.2 0.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.15 KKK23928.1 - 1.7e-141 470.9 0.0 2.3e-141 470.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KKK23928.1 - 0.0001 21.2 0.0 0.00018 20.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SelA PF03841.8 KKK23928.1 - 0.00028 19.7 0.0 0.00076 18.3 0.0 1.6 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Met_gamma_lyase PF06838.6 KKK23928.1 - 0.002 16.5 0.0 0.0085 14.4 0.0 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 KKK23928.1 - 0.0023 17.0 0.0 0.0055 15.7 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KKK23928.1 - 0.0047 16.1 0.0 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase GDC-P PF02347.11 KKK23928.1 - 0.038 12.7 0.0 0.075 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage system P-protein DUF2611 PF11022.3 KKK23929.1 - 3.2e-30 104.0 0.2 3.4e-30 103.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) COesterase PF00135.23 KKK23930.1 - 5.2e-90 302.6 0.0 8.9e-90 301.8 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK23930.1 - 0.00014 21.5 0.4 0.0019 17.8 0.2 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK23930.1 - 0.0019 17.4 0.1 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family ACPS PF01648.15 KKK23931.1 - 5.3e-16 58.4 0.0 1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PHP PF02811.14 KKK23931.1 - 3e-09 36.9 0.0 5.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 PHP domain ELFV_dehydrog PF00208.16 KKK23932.1 - 2.4e-61 207.4 0.0 4.6e-61 206.4 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KKK23932.1 - 1.8e-19 68.8 0.0 1.1e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KKK23932.1 - 0.0018 17.8 0.0 0.0062 16.1 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain RIX1 PF08167.7 KKK23933.1 - 2.9e-57 192.9 0.7 2.9e-57 192.9 0.5 2.1 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis MBOAT_2 PF13813.1 KKK23935.1 - 2.7e-21 75.4 4.5 7.2e-21 74.0 3.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family TPR_2 PF07719.12 KKK23936.1 - 3.7e-10 38.9 9.4 0.023 14.5 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 KKK23936.1 - 7.9e-08 31.8 10.3 0.00024 20.6 0.0 5.1 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.1 KKK23936.1 - 2.3e-07 30.8 20.1 3.4 8.5 0.0 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK23936.1 - 3.2e-07 29.6 7.4 0.0063 16.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK23936.1 - 2.2e-06 27.0 3.5 7 6.6 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK23936.1 - 0.00011 22.0 14.5 0.67 9.9 0.0 5.2 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK23936.1 - 0.00013 22.5 18.1 1 10.0 0.0 6.2 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK23936.1 - 0.00049 19.6 7.4 1.3 8.9 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KKK23936.1 - 0.0011 19.2 6.1 2.7 8.3 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK23936.1 - 0.0018 18.3 0.3 15 6.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK23936.1 - 0.0027 17.5 3.1 7.6 6.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TRP PF06011.7 KKK23937.1 - 1.6e-163 544.4 27.5 2e-163 544.0 19.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KKK23937.1 - 1.1e-43 148.6 0.7 2e-43 147.8 0.5 1.4 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 KKK23937.1 - 4.5e-05 22.8 0.6 0.0015 17.9 0.0 2.8 3 0 0 3 3 3 1 Glycoprotein UL132 VirB3 PF05101.8 KKK23937.1 - 0.00027 20.8 6.3 0.044 13.7 0.0 3.6 3 0 0 3 3 3 2 Type IV secretory pathway, VirB3-like protein DUF843 PF05814.6 KKK23937.1 - 0.79 9.5 11.7 1.5 8.6 0.2 3.7 3 1 1 4 4 4 0 Baculovirus protein of unknown function (DUF843) Orbi_NS3 PF01616.11 KKK23937.1 - 1.7 7.5 4.5 1.1 8.2 0.0 2.8 3 0 0 3 3 3 0 Orbivirus NS3 DEAD PF00270.24 KKK23938.1 - 5.2e-44 149.7 0.0 1.2e-43 148.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK23938.1 - 1.2e-20 73.1 0.0 2.5e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KKK23938.1 - 1.5e-20 72.4 0.2 2.6e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DUF3306 PF11748.3 KKK23938.1 - 0.11 13.1 6.1 0.21 12.2 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) ResIII PF04851.10 KKK23938.1 - 0.14 11.9 3.3 0.56 10.0 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Spore_coat_CotO PF14153.1 KKK23938.1 - 0.23 10.8 13.0 0.39 10.1 9.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Myc_N PF01056.13 KKK23938.1 - 0.24 10.5 7.4 0.36 9.9 5.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Vfa1 PF08432.5 KKK23938.1 - 2.4 8.1 14.2 4.2 7.3 9.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 KKK23938.1 - 2.6 6.4 16.5 3.7 5.9 11.4 1.1 1 0 0 1 1 1 0 Daxx Family Na_trans_assoc PF06512.8 KKK23938.1 - 4.1 7.3 12.6 8 6.3 8.7 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated IncA PF04156.9 KKK23938.1 - 4.7 6.7 10.6 1.5 8.3 5.4 1.6 2 0 0 2 2 2 0 IncA protein BTV_NS2 PF04514.7 KKK23938.1 - 5 5.8 13.1 9.6 4.9 9.1 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RNA_pol_3_Rpc31 PF11705.3 KKK23938.1 - 5.4 6.8 17.0 11 5.8 11.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Glyco_hydro_47 PF01532.15 KKK23939.1 - 1.4e-155 518.4 0.0 1.5e-155 518.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Stb3 PF10330.4 KKK23940.1 - 1e-37 127.6 0.0 1.6e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein YrhK PF14145.1 KKK23941.1 - 1.6 8.4 5.4 4.6 6.9 0.1 3.1 3 0 0 3 3 3 0 YrhK-like protein HNH_2 PF13391.1 KKK23942.1 - 8.8e-15 54.2 0.1 4.7e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Cript PF10235.4 KKK23943.1 - 5.5e-38 129.2 1.7 5.5e-38 129.2 1.2 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 KKK23943.1 - 0.00022 20.9 11.5 0.0053 16.5 6.1 2.6 2 1 1 3 3 3 2 Double zinc ribbon zf-ribbon_3 PF13248.1 KKK23943.1 - 0.001 18.2 8.4 0.16 11.2 0.9 3.3 2 1 1 3 3 3 2 zinc-ribbon domain eIF-4B PF06273.6 KKK23943.1 - 0.011 14.5 1.1 0.011 14.5 0.8 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Rad50_zn_hook PF04423.9 KKK23943.1 - 0.014 14.8 3.4 0.028 13.8 2.4 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zinc_ribbon_2 PF13240.1 KKK23943.1 - 0.18 11.3 11.2 7 6.2 0.1 3.2 2 1 1 3 3 3 0 zinc-ribbon domain zf-HYPF PF07503.7 KKK23943.1 - 0.61 9.5 11.0 0.71 9.3 3.9 2.3 2 0 0 2 2 2 0 HypF finger DUF2616 PF11077.3 KKK23943.1 - 1 8.8 6.6 0.066 12.7 1.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Prok-RING_4 PF14447.1 KKK23943.1 - 1.2 8.7 6.2 2.7 7.6 0.6 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 KKK23943.1 - 2.5 8.0 13.1 7.2 6.5 5.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.1 KKK23943.1 - 3.2 7.5 14.3 46 3.7 7.1 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF581 PF04570.9 KKK23943.1 - 4.3 6.7 12.2 20 4.5 1.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF581) Kazal_2 PF07648.10 KKK23943.1 - 4.8 7.2 10.4 2.6 8.0 2.4 3.0 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain DUF2039 PF10217.4 KKK23943.1 - 4.9 7.2 17.8 1.7 8.7 7.8 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) zf-TFIIB PF13453.1 KKK23943.1 - 5.2 6.3 7.3 2.9 7.1 0.0 2.8 3 0 0 3 3 3 0 Transcription factor zinc-finger MRP-L46 PF11788.3 KKK23945.1 - 1.5e-35 122.2 1.2 3.1e-35 121.1 0.8 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KKK23945.1 - 0.0024 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.15 KKK23946.1 - 2e-46 158.4 0.0 2.6e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 KKK23946.1 - 0.072 12.5 0.0 0.49 9.8 0.0 2.1 2 0 0 2 2 2 0 3'-5' exonuclease AAA_23 PF13476.1 KKK23975.1 - 5.8e-30 105.1 1.0 5.8e-30 105.1 0.7 8.2 1 1 1 2 2 2 1 AAA domain SbcCD_C PF13558.1 KKK23975.1 - 1.8e-11 43.7 0.0 5.8e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KKK23975.1 - 1.1e-07 31.2 0.0 1.1e-07 31.2 0.0 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK23975.1 - 5.7e-05 23.2 0.0 0.0079 16.1 0.0 4.5 4 2 0 4 4 4 2 AAA domain AAA_13 PF13166.1 KKK23975.1 - 7.8e-05 21.3 134.9 0.00027 19.5 0.0 7.1 2 1 4 6 6 6 3 AAA domain KNOX2 PF03791.8 KKK23975.1 - 0.00022 20.4 0.1 0.017 14.4 0.0 3.6 3 0 0 3 3 3 1 KNOX2 domain AAA_29 PF13555.1 KKK23975.1 - 0.00082 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 KKK23975.1 - 0.017 14.7 0.3 0.017 14.7 0.2 2.9 3 1 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Reo_sigmaC PF04582.7 KKK23975.1 - 4.3 6.4 37.5 1.3 8.1 1.1 6.9 4 3 4 8 8 8 0 Reovirus sigma C capsid protein Glyco_transf_21 PF13506.1 KKK23976.1 - 1.6e-12 47.0 0.1 1.4e-05 24.4 0.0 3.8 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KKK23976.1 - 4.6e-11 42.9 0.0 1.3e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KKK23976.1 - 0.00028 20.6 0.0 0.0074 15.9 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ank_2 PF12796.2 KKK23977.1 - 1.1e-23 83.3 7.4 2.3e-12 47.0 0.6 1.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KKK23977.1 - 1.2e-12 47.0 0.7 1.7e-10 40.1 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KKK23977.1 - 1.6e-10 40.1 1.1 3.2e-07 29.9 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KKK23977.1 - 1.9e-09 37.4 3.5 1.9e-06 27.9 0.3 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK23977.1 - 6e-07 29.8 0.6 3.3e-05 24.2 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) AlaDh_PNT_N PF05222.10 KKK23977.1 - 0.097 12.6 0.1 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain Cupin_2 PF07883.6 KKK23978.1 - 8.2e-07 28.4 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KKK23978.1 - 0.033 13.5 0.0 0.083 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KKK23978.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin Peptidase_M54 PF07998.6 KKK23979.1 - 1.5e-06 28.1 0.1 2.9e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M54 Endonuclease_1 PF04231.8 KKK23979.1 - 0.00013 21.9 0.1 0.00017 21.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease I SR-25 PF10500.4 KKK23979.1 - 0.0043 16.5 13.4 0.0059 16.1 9.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF1025 PF06262.6 KKK23979.1 - 0.098 12.4 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Possibl zinc metallo-peptidase DUF3446 PF11928.3 KKK23979.1 - 0.32 11.1 8.7 0.58 10.3 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Innate_immun PF12782.2 KKK23979.1 - 0.58 9.3 4.8 0.73 8.9 3.3 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family CPSF73-100_C PF11718.3 KKK23979.1 - 3 7.1 4.8 4.1 6.6 3.4 1.2 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Reprolysin PF01421.14 KKK23979.1 - 3.8 7.0 6.1 0.4 10.2 0.1 2.0 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease RAP1 PF07218.6 KKK23979.1 - 6.6 4.6 5.3 7.8 4.4 3.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_3 PF07859.8 KKK23980.1 - 4.4e-43 147.3 0.0 5.6e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK23980.1 - 2e-10 40.0 2.8 8.2e-10 38.0 2.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KKK23980.1 - 2.2e-05 24.2 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK23980.1 - 0.099 11.8 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2296 PF10058.4 KKK23981.1 - 2.1e-19 69.0 0.1 3.6e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF2360 PF10152.4 KKK23981.1 - 1 9.6 16.5 0.2 11.9 2.3 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Mit_KHE1 PF10173.4 KKK23983.1 - 1.1e-66 224.2 1.2 1.5e-66 223.8 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF4478 PF14793.1 KKK23983.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) DUF588 PF04535.7 KKK23984.1 - 0.03 13.9 1.1 0.057 12.9 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Ilm1 PF10311.4 KKK23984.1 - 0.087 12.3 0.3 0.14 11.6 0.2 1.4 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 Cupin_2 PF07883.6 KKK23985.1 - 2.9e-08 33.0 0.7 4.5e-08 32.4 0.5 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KKK23985.1 - 9.1e-08 31.6 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 KKK23985.1 - 2.4e-05 24.3 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 KKK23985.1 - 7e-05 22.5 0.0 8.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KKK23985.1 - 0.044 13.4 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cullin PF00888.17 KKK23986.1 - 1.2e-205 684.5 11.9 1.2e-205 684.5 8.2 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KKK23986.1 - 1.5e-27 95.2 3.4 1.5e-27 95.2 2.4 3.5 3 0 0 3 3 3 1 Cullin protein neddylation domain TipAS PF07739.8 KKK23986.1 - 0.0072 16.6 0.3 0.14 12.4 0.0 3.2 3 0 0 3 3 3 1 TipAS antibiotic-recognition domain WGG PF10273.4 KKK23986.1 - 0.15 12.1 3.4 24 5.1 0.0 4.2 6 0 0 6 6 6 0 Pre-rRNA-processing protein TSR2 End3 PF12761.2 KKK23987.1 - 8.8e-73 244.1 0.9 1.3e-72 243.5 0.6 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KKK23987.1 - 2e-51 172.0 0.2 4.2e-48 161.3 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KKK23987.1 - 4.8e-09 34.8 0.2 1.3e-07 30.3 0.2 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KKK23987.1 - 1e-06 28.2 0.2 3.5e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KKK23987.1 - 2.5e-06 26.8 0.3 0.00027 20.5 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KKK23987.1 - 4e-06 26.8 0.3 5.8e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KKK23987.1 - 0.0006 19.0 0.2 0.002 17.3 0.1 1.9 1 0 0 1 1 1 1 EF hand Rabaptin PF03528.10 KKK23987.1 - 0.04 13.8 3.1 0.11 12.4 1.9 1.9 2 0 0 2 2 2 0 Rabaptin Phlebovirus_NSM PF07246.6 KKK23987.1 - 0.54 9.3 3.3 0.85 8.7 2.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Ribosomal_S8 PF00410.14 KKK23988.1 - 8.2e-24 83.8 0.0 1.1e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.17 KKK23989.1 - 9.6e-18 64.7 0.0 1.2e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PINIT PF14324.1 KKK23989.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 PINIT domain Glyco_hydro_18 PF00704.23 KKK23992.1 - 3.5e-74 250.2 5.8 6.4e-74 249.4 4.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KKK23992.1 - 3.5e-11 42.8 15.5 3.5e-11 42.8 10.8 4.2 4 1 0 4 4 4 2 Chitin recognition protein Dicty_REP PF05086.7 KKK23992.1 - 9.6 3.8 12.9 15 3.1 9.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ank_2 PF12796.2 KKK23993.1 - 2e-31 108.1 0.0 7.2e-12 45.4 0.0 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KKK23993.1 - 5.8e-22 76.3 4.7 0.0011 18.6 0.2 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 KKK23993.1 - 5.3e-20 69.5 0.6 0.012 15.7 0.1 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 KKK23993.1 - 6.8e-18 64.6 2.3 6.4e-06 26.5 0.0 6.7 3 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK23993.1 - 8.1e-13 48.1 4.0 0.036 14.3 0.0 7.4 3 2 5 8 8 8 4 Ankyrin repeats (many copies) SecD_SecF PF02355.11 KKK23994.1 - 0.19 10.9 1.1 0.21 10.7 0.4 1.4 1 1 0 1 1 1 0 Protein export membrane protein MFS_1 PF07690.11 KKK23994.1 - 0.24 10.0 7.0 0.27 9.8 4.8 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily OapA_N PF08525.6 KKK23994.1 - 2.1 8.2 8.2 0.15 11.9 1.9 1.9 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Kinesin PF00225.18 KKK23995.1 - 1.1e-80 270.8 3.0 1.1e-80 270.8 2.1 2.3 3 0 0 3 3 3 1 Kinesin motor domain HHH PF00633.18 KKK23995.1 - 4.5e-07 29.1 0.8 0.022 14.4 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.1 KKK23995.1 - 0.0015 18.6 0.2 0.0054 16.8 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain SRA1 PF07304.6 KKK23995.1 - 0.019 14.6 1.9 0.026 14.2 0.4 1.9 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) HHH_3 PF12836.2 KKK23995.1 - 0.032 14.1 1.2 4.1 7.4 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix motif Methyltransf_23 PF13489.1 KKK23996.1 - 3.4e-15 56.1 0.0 4.2e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK23996.1 - 2.3e-12 47.2 0.0 4.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK23996.1 - 2.1e-11 43.6 0.0 2.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK23996.1 - 3e-11 43.8 0.0 4.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK23996.1 - 1.2e-10 41.5 0.0 2.5e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK23996.1 - 2.4e-10 40.7 0.0 3.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK23996.1 - 2.2e-05 23.6 0.1 5.1e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KKK23996.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KKK23996.1 - 0.0017 17.1 0.0 0.0024 16.6 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 KKK23996.1 - 0.0032 16.8 0.0 0.0056 16.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PCI PF01399.22 KKK23997.1 - 1.1e-08 35.3 0.0 2.6e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain GrpE PF01025.14 KKK23997.1 - 0.011 15.2 0.4 0.022 14.3 0.3 1.4 1 0 0 1 1 1 0 GrpE HEM4 PF02602.10 KKK23998.1 - 2.6e-30 105.3 0.0 9.2e-30 103.5 0.0 1.8 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.20 KKK23999.1 - 2.8e-74 249.5 0.0 3.4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23999.1 - 3.6e-32 111.4 0.0 4.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK23999.1 - 0.00055 18.9 0.0 0.0015 17.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KKK23999.1 - 0.0022 17.0 0.1 0.0037 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK23999.1 - 0.013 15.1 0.1 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK23999.1 - 0.06 12.1 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Epimerase PF01370.16 KKK24000.1 - 4.6e-13 49.1 0.1 1.2e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK24000.1 - 9.1e-13 48.6 0.0 1.6e-09 37.9 0.0 2.2 1 1 1 2 2 2 2 NADH(P)-binding NmrA PF05368.8 KKK24000.1 - 2.9e-12 46.3 0.0 1.8e-09 37.2 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.14 KKK24000.1 - 2.3e-10 39.6 0.1 4.4e-10 38.7 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KKK24000.1 - 0.0001 21.2 0.0 0.015 14.1 0.0 2.4 1 1 1 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 KKK24000.1 - 0.0023 16.9 0.1 0.0054 15.6 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KKK24000.1 - 0.0027 17.6 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KKK24000.1 - 0.0055 15.7 0.0 0.0079 15.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DDE_Tnp_1_3 PF13612.1 KKK24000.1 - 0.019 14.7 0.0 0.076 12.7 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain DLH PF01738.13 KKK24001.1 - 1.3e-23 83.4 0.0 1.6e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK24001.1 - 0.0017 18.1 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK24001.1 - 0.0052 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK24001.1 - 0.13 12.0 0.0 1.1 9.1 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Sec23_trunk PF04811.10 KKK24002.1 - 3.7e-70 236.0 0.0 7.6e-70 235.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KKK24002.1 - 1.5e-22 78.9 0.0 2.3e-21 75.1 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KKK24002.1 - 6.9e-18 63.9 5.3 1.2e-17 63.1 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KKK24002.1 - 5.6e-17 62.0 0.0 1.4e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KKK24002.1 - 8.4e-09 35.0 0.0 2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Gaa1 PF04114.9 KKK24003.1 - 8.5e-96 321.6 8.4 3.3e-95 319.6 5.8 1.8 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 KKK24003.1 - 4.8e-13 49.3 10.4 4.8e-13 49.3 7.2 3.1 4 0 0 4 4 4 1 Rhomboid family ATG11 PF10377.4 KKK24010.1 - 8.2e-41 138.9 0.0 8.2e-41 138.9 0.0 3.3 3 0 0 3 3 3 1 Autophagy-related protein 11 CENP-Q PF13094.1 KKK24010.1 - 0.005 16.8 8.8 0.005 16.8 6.1 5.5 1 1 4 5 5 5 1 CENP-Q, a CENPA-CAD centromere complex subunit WEMBL PF05701.6 KKK24010.1 - 0.007 14.8 61.8 0.083 11.3 19.4 2.5 2 0 0 2 2 2 2 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 KKK24010.1 - 0.011 15.4 11.2 0.011 15.4 7.8 6.3 5 1 0 5 5 5 0 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.7 KKK24010.1 - 0.14 11.9 0.1 0.14 11.9 0.1 7.1 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 KKK24010.1 - 0.15 11.1 18.9 0.33 10.0 4.6 3.6 2 2 0 3 3 3 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KKK24010.1 - 0.86 9.7 40.6 0.063 13.3 5.5 5.6 5 2 2 7 7 7 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 KKK24010.1 - 2.3 5.4 61.8 0.018 12.3 31.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_11 PF13414.1 KKK24012.1 - 2.6e-44 148.7 26.3 1.6e-16 59.6 1.6 5.5 3 2 2 5 5 5 5 TPR repeat TPR_2 PF07719.12 KKK24012.1 - 2.7e-32 108.0 12.5 2.1e-05 24.0 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KKK24012.1 - 5.8e-32 107.9 12.5 1.1e-06 27.9 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat DnaJ PF00226.26 KKK24012.1 - 3.5e-27 93.9 2.9 1.2e-26 92.2 1.1 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.1 KKK24012.1 - 1e-26 92.9 16.4 4.3e-06 27.2 0.0 5.9 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 KKK24012.1 - 2e-22 79.3 19.9 3.1e-07 30.6 0.4 5.8 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 KKK24012.1 - 2.2e-15 55.1 5.7 0.017 14.8 0.0 7.3 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KKK24012.1 - 3.6e-14 51.9 21.8 0.0037 17.7 0.1 8.0 6 2 3 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KKK24012.1 - 4.8e-13 47.8 3.3 0.037 13.8 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KKK24012.1 - 1.1e-12 47.8 4.7 0.00026 21.0 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KKK24012.1 - 1.2e-12 47.0 15.4 0.0081 16.2 0.3 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 KKK24012.1 - 9.9e-11 41.3 10.9 0.041 14.3 0.0 7.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK24012.1 - 2.7e-10 40.0 11.4 0.0094 15.8 0.2 5.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 KKK24012.1 - 5.7e-09 35.7 10.6 0.038 13.8 0.1 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KKK24012.1 - 4.2e-07 29.7 3.0 0.39 10.6 0.0 4.4 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 KKK24012.1 - 9.1e-06 26.0 4.5 0.056 13.7 0.0 4.0 3 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_15 PF13429.1 KKK24012.1 - 1.3e-05 24.4 5.5 1 8.3 0.0 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KKK24012.1 - 9.2e-05 22.4 5.7 2.1 8.4 0.2 4.6 3 2 1 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KKK24012.1 - 0.037 13.2 8.6 26 4.1 0.0 5.3 6 0 0 6 6 6 0 SHNi-TPR DUF2225 PF09986.4 KKK24012.1 - 0.065 12.6 0.1 1.8 7.9 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.9 KKK24012.1 - 0.2 12.1 0.1 0.2 12.1 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 KKK24012.1 - 0.21 11.5 0.1 0.21 11.5 0.1 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK24012.1 - 0.54 10.2 10.7 9.3 6.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 KKK24012.1 - 0.67 9.8 4.3 2.6 7.9 0.1 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Ribonuc_L-PSP PF01042.16 KKK24014.1 - 2.2e-17 62.9 0.0 3.5e-17 62.2 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Amidohydro_2 PF04909.9 KKK24015.1 - 2.4e-41 142.1 0.1 2.9e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.17 KKK24016.1 - 7.2e-147 489.4 0.0 8.2e-147 489.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box-like PF12937.2 KKK24017.1 - 0.0078 15.9 0.1 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like Cas_CXXC_CXXC PF09706.5 KKK24018.1 - 0.075 13.2 4.0 11 6.2 0.1 4.0 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-RING_4 PF14570.1 KKK24018.1 - 1.5 8.4 11.6 15 5.2 0.0 4.8 5 0 0 5 5 5 0 RING/Ubox like zinc-binding domain Exo_endo_phos PF03372.18 KKK24019.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Fungal_trans PF04082.13 KKK24020.1 - 5.7e-13 48.3 1.8 2.3e-12 46.3 1.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24020.1 - 6.7e-07 29.1 14.7 1.4e-06 28.1 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_C PF05199.8 KKK24021.1 - 1e-33 116.6 1.5 1.4e-32 112.9 0.3 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KKK24021.1 - 1.1e-31 110.1 0.0 1.7e-28 99.6 0.0 3.0 1 1 1 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK24021.1 - 0.0022 16.8 0.3 0.0087 14.9 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK24021.1 - 0.0036 17.2 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK24021.1 - 0.004 17.1 0.2 0.013 15.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK24021.1 - 0.015 14.2 0.2 0.3 9.9 0.1 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KKK24021.1 - 0.028 14.4 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KKK24021.1 - 0.079 12.3 0.4 0.16 11.4 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KKK24021.1 - 0.19 10.1 0.2 2.1 6.7 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein RVT_1 PF00078.22 KKK24022.1 - 3.2e-05 23.4 0.0 6.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) U5_2-snRNA_bdg PF10597.4 KKK24022.1 - 0.12 11.9 0.1 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 LysM PF01476.15 KKK24023.1 - 2.6e-24 84.8 0.0 3.2e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 LysM domain CorA PF01544.13 KKK24024.1 - 0.00015 20.8 1.4 0.0003 19.9 0.0 2.1 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein CIAPIN1 PF05093.8 KKK24025.1 - 1.3e-34 118.2 2.1 2e-34 117.6 1.4 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF1616 PF07760.6 KKK24034.1 - 0.038 13.1 0.2 0.038 13.1 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1616) RRM_6 PF14259.1 KKK24035.1 - 1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK24035.1 - 2e-05 24.1 0.0 3.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK24035.1 - 0.00017 21.3 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 KKK24035.1 - 0.00085 18.6 0.9 0.00085 18.6 0.6 1.8 2 0 0 2 2 2 1 Lsm interaction motif C2 PF00168.25 KKK24036.1 - 1.1e-10 41.2 0.1 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain SSP160 PF06933.6 KKK24036.1 - 5.4 4.8 7.0 7.9 4.3 4.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PHD PF00628.24 KKK24050.1 - 6.2e-09 35.4 7.5 1e-08 34.7 5.2 1.3 1 0 0 1 1 1 1 PHD-finger DUF1423 PF07227.6 KKK24050.1 - 0.93 8.0 2.2 1.4 7.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) PHD_2 PF13831.1 KKK24050.1 - 1 8.7 5.0 1.7 8.0 3.5 1.4 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.20 KKK24051.1 - 9.7e-66 221.5 0.0 1.7e-65 220.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24051.1 - 2.5e-35 121.7 0.0 1.3e-33 116.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK24051.1 - 1.4e-07 30.7 0.1 5.9e-06 25.4 0.1 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KKK24051.1 - 0.0036 17.0 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK24051.1 - 0.017 13.9 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Vac_ImportDeg PF09783.4 KKK24052.1 - 3.1e-71 238.5 1.1 4e-71 238.1 0.8 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 KKK24053.1 - 4.6e-76 253.3 0.3 5.7e-76 253.0 0.2 1.1 1 0 0 1 1 1 1 Mago nashi protein DAGK_cat PF00781.19 KKK24054.1 - 8.3e-25 86.7 0.0 1.4e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.15 KKK24055.1 - 3.8e-95 319.1 9.1 6e-95 318.5 6.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KKK24055.1 - 3.6e-62 207.8 0.0 1.1e-61 206.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KKK24055.1 - 1.4e-61 206.2 0.9 3.1e-61 205.1 0.6 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KKK24055.1 - 2.5e-11 43.6 9.1 3e-07 30.6 0.0 4.7 2 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 KKK24055.1 - 1.9e-06 27.8 3.1 0.022 14.5 0.0 3.5 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KKK24055.1 - 0.00051 20.4 0.9 0.11 13.0 0.0 4.3 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 KKK24055.1 - 0.0013 18.6 1.4 0.43 10.7 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat AP4E_app_platf PF14807.1 KKK24055.1 - 0.024 14.8 0.1 0.1 12.8 0.0 2.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Sugar_tr PF00083.19 KKK24056.1 - 1e-126 423.2 31.3 1.1e-126 423.0 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24056.1 - 3.9e-24 85.0 56.2 2.9e-21 75.5 22.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK24056.1 - 7.6e-06 24.5 31.8 0.00027 19.4 6.7 3.4 3 1 0 3 3 3 3 MFS/sugar transport protein TPR_19 PF14559.1 KKK24056.1 - 0.16 12.3 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1_like PF12832.2 KKK24056.1 - 0.23 11.2 0.1 0.23 11.2 0.0 4.0 3 1 0 3 3 3 0 MFS_1 like family DUF3154 PF11351.3 KKK24056.1 - 0.25 11.0 1.7 0.42 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Phage_holin_2 PF04550.7 KKK24056.1 - 0.57 10.3 5.2 0.84 9.7 2.7 2.0 2 0 0 2 2 2 0 Phage holin family 2 Nuc_sug_transp PF04142.10 KKK24057.1 - 2.4e-09 36.6 1.9 4.1e-09 35.8 1.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KKK24057.1 - 6.5e-08 31.8 7.6 1.1e-07 31.1 5.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KKK24057.1 - 9.4e-07 28.9 27.4 0.00018 21.5 4.8 3.2 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 KKK24057.1 - 4.8e-05 23.0 16.1 0.022 14.3 5.1 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 KKK24057.1 - 0.0018 18.4 7.1 0.0018 18.4 4.9 3.4 2 1 0 3 3 3 1 Multidrug resistance efflux transporter Oxidored_q1_C PF01010.14 KKK24057.1 - 0.019 14.4 0.3 0.032 13.7 0.2 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus MerC PF03203.9 KKK24057.1 - 1.1 9.6 12.5 1.7 9.0 4.4 3.6 1 1 1 3 3 3 0 MerC mercury resistance protein O-antigen_lig PF13425.1 KKK24057.1 - 5.6 6.9 17.8 0.077 12.9 5.1 2.7 1 1 1 2 2 2 0 O-antigen ligase like membrane protein MAGE PF01454.14 KKK24059.1 - 5.3e-47 159.6 0.0 7.8e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 MAGE family Adaptin_N PF01602.15 KKK24060.1 - 1.6e-140 468.9 3.0 1.9e-140 468.6 2.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KKK24060.1 - 2.2e-19 69.8 0.0 4e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KKK24060.1 - 5.5e-07 29.7 1.6 0.07 13.4 0.0 4.0 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 KKK24060.1 - 0.00098 19.0 2.0 0.014 15.2 0.5 3.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KKK24060.1 - 0.0023 18.3 0.7 6.9 7.2 0.1 4.9 4 1 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 KKK24060.1 - 0.0042 17.0 2.1 13 6.1 0.0 4.8 4 1 0 4 4 4 1 HEAT repeat TIP120 PF08623.5 KKK24060.1 - 0.0064 16.1 0.6 0.033 13.7 0.0 2.3 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Arm PF00514.18 KKK24060.1 - 0.031 14.1 0.2 31 4.5 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat MBOAT PF03062.14 KKK24061.1 - 1.2e-35 123.1 22.7 1.2e-35 123.1 15.8 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Med15_fungi PF05397.7 KKK24062.1 - 4e-38 129.9 0.0 4e-38 129.9 0.0 6.0 7 0 0 7 7 7 1 Mediator complex subunit 15 zf-DHHC PF01529.15 KKK24062.1 - 3.3 7.0 6.4 14 5.0 4.5 2.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Plasmodium_Vir PF05795.6 KKK24062.1 - 3.9 6.5 5.2 15 4.6 3.6 2.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LMBR1 PF04791.11 KKK24063.1 - 8.2e-30 103.8 2.8 1.3e-29 103.1 2.0 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein BAG PF02179.11 KKK24063.1 - 9.6e-11 41.6 0.2 2.2e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 BAG domain FUSC PF04632.7 KKK24063.1 - 5.6e-05 21.7 9.0 8.2e-05 21.2 0.7 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein family ubiquitin PF00240.18 KKK24063.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family HemY_N PF07219.8 KKK24063.1 - 0.17 11.4 12.1 0.77 9.3 3.3 3.4 3 0 0 3 3 3 0 HemY protein N-terminus Glutaredoxin PF00462.19 KKK24066.1 - 5.7e-22 77.4 0.0 8e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 KKK24066.1 - 0.0019 18.4 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 KKK24066.1 - 0.015 15.4 0.1 0.03 14.5 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.1 KKK24066.1 - 0.015 14.7 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin PF00085.15 KKK24066.1 - 0.017 14.7 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.1 KKK24066.1 - 0.047 13.9 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 KKK24066.1 - 0.049 13.1 0.0 0.051 13.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 KKK24066.1 - 0.066 12.7 0.3 0.28 10.6 0.1 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_7 PF13899.1 KKK24066.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 KKK24066.1 - 0.14 12.1 0.4 1.3 9.0 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.1 KKK24066.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_8 PF13905.1 KKK24066.1 - 0.16 12.1 0.1 0.28 11.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Chalcone PF02431.10 KKK24067.1 - 1.2e-51 174.9 0.0 1.8e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Chalcone-flavanone isomerase BSP_II PF05432.6 KKK24067.1 - 0.41 9.8 5.6 0.73 9.0 3.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ank_2 PF12796.2 KKK24068.1 - 3.4e-13 49.7 0.1 8.1e-09 35.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KKK24068.1 - 1.4e-09 37.2 0.0 2.4e-05 23.8 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KKK24068.1 - 4.9e-09 35.5 0.0 0.0017 18.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KKK24068.1 - 3.8e-08 33.3 0.1 0.081 13.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK24068.1 - 1.1e-05 25.8 0.6 0.004 17.6 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) GTP_EFTU PF00009.22 KKK24069.1 - 1.7e-56 190.6 0.0 2.8e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PALP PF00291.20 KKK24069.1 - 4.6e-52 177.1 0.2 8e-52 176.3 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GTP_EFTU_D3 PF03143.12 KKK24069.1 - 2.8e-35 120.4 0.0 7.4e-35 119.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KKK24069.1 - 7.5e-16 58.0 1.6 2.8e-15 56.1 1.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KKK24069.1 - 0.00011 21.7 0.3 0.00029 20.3 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KKK24069.1 - 0.0057 16.6 0.1 0.02 14.8 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 KKK24069.1 - 0.081 12.6 0.3 1.3 8.6 0.2 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Cyt-b5 PF00173.23 KKK24071.1 - 3.8e-23 81.0 0.1 4.8e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UCH PF00443.24 KKK24072.1 - 5e-54 183.2 0.0 7.5e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK24072.1 - 1e-30 107.1 0.0 1.8e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KKK24072.1 - 0.00069 19.9 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.6 KKK24074.1 - 0.00023 21.0 0.0 0.00029 20.7 0.0 1.1 1 0 0 1 1 1 1 USP8 dimerisation domain VHS PF00790.14 KKK24075.1 - 1e-40 138.6 0.7 1.2e-39 135.1 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KKK24075.1 - 2.4e-16 59.3 1.4 3.9e-16 58.7 0.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KKK24075.1 - 0.00021 20.6 11.3 0.0038 16.6 1.2 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KKK24075.1 - 0.022 14.1 0.2 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 KKK24075.1 - 0.054 13.3 0.4 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger ADH_N PF08240.7 KKK24077.1 - 1.1e-21 76.6 2.1 1.1e-21 76.6 1.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KKK24077.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 KKK24077.1 - 0.035 13.6 0.0 1.4 8.4 0.0 2.7 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.2 KKK24078.1 - 2.6e-21 76.5 0.0 3.1e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK24078.1 - 1.2e-17 64.3 0.0 3.7e-17 62.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK24078.1 - 2.5e-07 30.5 0.0 1.3e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KKK24078.1 - 5.6e-05 21.7 0.0 0.00015 20.3 0.0 1.7 1 1 0 1 1 1 1 Ndr family Ribonuclease_3 PF00636.21 KKK24080.1 - 7.9e-05 23.0 0.0 0.00026 21.4 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KKK24080.1 - 0.0032 17.4 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Sugar_tr PF00083.19 KKK24081.1 - 2.4e-104 349.4 24.1 2.8e-104 349.2 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24081.1 - 8.5e-26 90.4 36.2 8.1e-18 64.2 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KKK24081.1 - 0.018 13.1 0.1 0.018 13.1 0.1 2.1 2 1 0 2 2 2 0 Transmembrane secretion effector IlvC PF01450.14 KKK24081.1 - 0.15 11.9 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Metallophos PF00149.23 KKK24082.1 - 1.2e-06 28.0 3.4 0.00013 21.3 0.1 2.6 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK24082.1 - 1.5e-05 24.8 0.0 3.5e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA_U5-meth_tr PF05958.6 KKK24089.1 - 2.3e-11 43.0 0.0 3.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KKK24089.1 - 0.00021 20.9 0.0 0.00078 19.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TRAM PF01938.15 KKK24089.1 - 0.00066 19.4 0.2 0.0016 18.1 0.2 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.5 KKK24089.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 KKK24089.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S5_C PF03719.10 KKK24090.1 - 6.5e-22 76.5 0.0 2.1e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KKK24090.1 - 5.9e-09 35.5 1.0 2.5e-08 33.5 0.0 2.4 2 1 1 3 3 3 1 Ribosomal protein S5, N-terminal domain DNA_binding_1 PF01035.15 KKK24091.1 - 0.034 13.8 0.2 0.037 13.7 0.1 1.3 1 1 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Fungal_trans_2 PF11951.3 KKK24092.1 - 2.9e-10 39.3 0.7 1.3e-09 37.1 0.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Grp1_Fun34_YaaH PF01184.14 KKK24093.1 - 8.2e-65 218.0 16.3 1.3e-64 217.4 11.3 1.3 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family CitG PF01874.11 KKK24109.1 - 0.094 11.8 0.1 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase APH PF01636.18 KKK24110.1 - 1.7e-10 41.0 0.0 2.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK24110.1 - 1.3e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KKK24110.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 1 0 1 1 1 0 Ecdysteroid kinase CorA PF01544.13 KKK24128.1 - 1.3e-10 40.8 0.2 2.2e-10 40.0 0.1 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Gly_transf_sug PF04488.10 KKK24129.1 - 6.1e-12 45.8 0.1 1.6e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif CUB PF00431.15 KKK24129.1 - 0.097 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 CUB domain Actin PF00022.14 KKK24140.1 - 6.6e-134 446.2 0.0 7.5e-134 446.0 0.0 1.0 1 0 0 1 1 1 1 Actin MRP-S28 PF10213.4 KKK24141.1 - 7.4e-45 152.1 0.0 1.4e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF3006 PF11213.3 KKK24141.1 - 0.18 11.5 2.1 0.9 9.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Glyco_tran_28_C PF04101.11 KKK24142.1 - 7.7e-17 61.4 0.0 6.5e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KKK24142.1 - 3.7e-05 23.0 0.0 5.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 UDPGT PF00201.13 KKK24142.1 - 0.026 13.0 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase zf-PHD-like PF15446.1 KKK24143.1 - 5.9e-66 221.0 9.5 1.3e-65 219.8 6.6 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KKK24143.1 - 7.6e-58 195.6 0.1 1.4e-57 194.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KKK24143.1 - 8.2e-13 47.8 2.4 1.6e-12 46.8 1.7 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 KKK24143.1 - 9.6e-13 47.8 0.0 2.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 KKK24143.1 - 9.4e-12 44.4 1.5 1.7e-06 27.5 0.4 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 KKK24143.1 - 8.7e-06 25.3 3.5 8.7e-06 25.3 2.4 3.4 2 1 1 3 3 3 1 PHD-finger DEAD PF00270.24 KKK24143.1 - 0.00012 21.6 0.0 0.0005 19.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KKK24143.1 - 0.00019 21.3 0.0 0.0092 15.8 0.0 3.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit C1_1 PF00130.17 KKK24143.1 - 0.0044 16.7 9.7 0.025 14.2 1.3 3.7 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_22 PF13401.1 KKK24143.1 - 0.11 12.6 0.0 0.71 10.0 0.0 2.5 2 2 0 2 2 2 0 AAA domain PHD_2 PF13831.1 KKK24143.1 - 0.52 9.6 13.2 0.048 12.9 3.5 3.2 2 1 0 2 2 2 0 PHD-finger Velvet PF11754.3 KKK24144.1 - 3.9e-59 199.6 0.1 1.1e-58 198.1 0.1 1.8 1 1 0 1 1 1 1 Velvet factor SpoU_methylase PF00588.14 KKK24145.1 - 1.7e-25 89.5 0.0 1.5e-24 86.4 0.0 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KKK24145.1 - 7.2e-08 32.4 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Shadoo PF14999.1 KKK24146.1 - 0.23 11.3 9.7 0.4 10.5 6.7 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 KKK24146.1 - 0.47 10.8 10.5 0.65 10.4 6.6 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein PAP2 PF01569.16 KKK24148.1 - 4.2e-15 55.5 2.2 4.2e-15 55.5 1.5 2.0 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 KKK24148.1 - 0.0079 15.9 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 1 Divergent PAP2 family Dpy-30 PF05186.8 KKK24148.1 - 0.6 9.6 2.9 1.9 8.0 0.3 2.4 2 0 0 2 2 2 0 Dpy-30 motif DUF4131 PF13567.1 KKK24148.1 - 4.8 6.5 8.6 9.7 5.5 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF3402 PF11882.3 KKK24149.1 - 2.8e-167 556.9 0.0 3.6e-167 556.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KKK24149.1 - 8.4e-103 343.2 0.0 1.2e-102 342.7 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein RWD PF05773.17 KKK24150.1 - 2.1e-23 82.3 0.0 3.5e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KKK24150.1 - 9.7e-19 67.0 37.5 1.4e-13 50.5 2.7 4.0 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 KKK24150.1 - 0.0035 17.1 11.4 0.0035 17.1 7.9 3.7 2 1 1 3 3 3 1 Ring finger domain Amidohydro_1 PF01979.15 KKK24168.1 - 1.2e-21 77.7 0.0 4.8e-20 72.4 0.0 2.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KKK24168.1 - 5.9e-19 69.1 0.4 7.1e-18 65.6 0.3 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KKK24168.1 - 6.7e-09 35.4 0.1 1.7e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KKK24168.1 - 7.2e-08 32.0 0.0 0.00014 21.2 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_26 PF02156.10 KKK24168.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 26 Rad21_Rec8_N PF04825.8 KKK24170.1 - 9.1e-39 131.8 0.0 1.7e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KKK24170.1 - 4.4e-07 28.9 0.2 9.6e-07 27.8 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KKK24170.1 - 0.00026 20.6 0.2 0.0048 16.5 0.0 2.3 2 0 0 2 2 2 1 ScpA/B protein MFS_1 PF07690.11 KKK24171.1 - 4.4e-43 147.3 29.9 4.4e-43 147.3 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK24171.1 - 1.4e-07 30.1 3.0 2.9e-07 29.0 2.1 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KKK24171.1 - 0.0001 20.5 0.5 0.00016 19.9 0.3 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Ammonium_transp PF00909.16 KKK24172.1 - 5.3e-118 393.9 31.9 6.1e-118 393.7 22.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Flavokinase PF01687.12 KKK24173.1 - 1.4e-25 89.6 0.0 5.1e-25 87.7 0.0 1.9 1 1 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.13 KKK24173.1 - 0.0084 16.0 9.2 0.019 14.8 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KKK24173.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold PsbQ PF05757.6 KKK24173.1 - 2.2 7.6 5.7 3.9 6.8 4.0 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Hexokinase_2 PF03727.11 KKK24174.1 - 1.9e-85 285.9 0.0 2.5e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KKK24174.1 - 1.5e-73 246.5 0.0 1.9e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase PhnJ PF06007.6 KKK24174.1 - 0.024 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ COG4 PF08318.7 KKK24175.1 - 3.8e-110 367.7 0.0 5.6e-110 367.1 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein FA_desaturase PF00487.19 KKK24175.1 - 0.015 14.7 5.1 0.024 14.0 3.6 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Zip PF02535.17 KKK24175.1 - 0.077 11.9 0.7 0.13 11.2 0.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SIR2 PF02146.12 KKK24176.1 - 1.8e-55 187.3 0.0 2.5e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Nab1 PF04902.7 KKK24176.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved region in Nab1 WD40 PF00400.27 KKK24177.1 - 2.2e-10 39.9 0.2 0.0047 16.7 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2583 PF10762.4 KKK24177.1 - 0.16 12.1 0.8 0.33 11.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) E1-E2_ATPase PF00122.15 KKK24178.1 - 4.7e-80 267.9 0.2 8.7e-80 267.0 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK24178.1 - 2e-43 148.0 3.3 3.3e-43 147.3 0.0 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK24178.1 - 7.7e-30 104.9 0.0 7.3e-29 101.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK24178.1 - 6.4e-20 70.3 0.1 1.4e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KKK24178.1 - 3.9e-15 56.5 0.0 8.9e-15 55.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK24178.1 - 2.8e-14 52.8 0.0 5.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK24178.1 - 2.9e-06 27.0 1.1 7e-05 22.5 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L21e PF01157.13 KKK24187.1 - 8.7e-39 131.3 5.6 8.7e-39 131.3 3.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e 3H PF02829.9 KKK24187.1 - 0.026 14.5 0.4 0.026 14.5 0.3 1.5 2 0 0 2 2 2 0 3H domain Endonuc_Holl PF10107.4 KKK24187.1 - 0.049 13.3 0.1 0.069 12.8 0.1 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Surface_Ag_2 PF01617.12 KKK24187.1 - 0.063 12.4 0.3 0.076 12.2 0.2 1.2 1 0 0 1 1 1 0 Surface antigen WD40 PF00400.27 KKK24188.1 - 3.3e-25 86.9 13.4 1.9e-07 30.6 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KKK24188.1 - 3.5e-05 22.2 0.2 0.16 10.2 0.0 3.8 3 1 1 4 4 4 3 Cytochrome D1 heme domain PQQ_3 PF13570.1 KKK24188.1 - 0.0001 22.4 1.6 0.63 10.3 0.0 3.5 3 0 0 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.1 KKK24188.1 - 0.091 12.5 0.0 22 4.8 0.0 3.5 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region RRM_6 PF14259.1 KKK24189.1 - 3.3e-06 26.9 0.0 5.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK24189.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PX PF00787.19 KKK24190.1 - 9.7e-27 93.0 0.2 1.2e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 KKK24190.1 - 0.1 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus MIP-T3 PF10243.4 KKK24192.1 - 0.054 11.9 37.1 0.07 11.5 25.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 KKK24192.1 - 0.06 12.7 17.7 0.087 12.2 12.3 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 KKK24192.1 - 1.5 7.0 14.9 1.6 6.9 10.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3584 PF12128.3 KKK24193.1 - 9.2e-05 20.0 9.3 0.00013 19.4 6.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) BLOC1_2 PF10046.4 KKK24193.1 - 0.0028 17.7 2.1 0.0028 17.7 1.5 3.0 3 1 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 KKK24193.1 - 0.011 15.5 7.3 0.018 14.8 0.5 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.12 KKK24193.1 - 0.035 13.7 15.2 0.057 13.0 1.4 4.2 2 1 2 4 4 4 0 Prefoldin subunit CRIC_ras_sig PF10534.4 KKK24193.1 - 0.077 13.0 1.9 0.1 12.6 0.6 1.8 2 0 0 2 2 1 0 Connector enhancer of kinase suppressor of ras NPV_P10 PF05531.7 KKK24193.1 - 0.079 13.2 3.6 5.2 7.3 0.2 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein NAD_binding_10 PF13460.1 KKK24193.1 - 0.11 12.4 1.2 3.8 7.4 0.0 2.3 1 1 1 2 2 2 0 NADH(P)-binding Bap31 PF05529.7 KKK24193.1 - 0.13 11.7 9.1 0.19 11.1 0.0 3.1 3 1 0 3 3 3 0 B-cell receptor-associated protein 31-like FlaC_arch PF05377.6 KKK24193.1 - 0.21 11.5 6.2 4.7 7.1 0.6 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 KKK24193.1 - 0.34 10.0 4.0 0.64 9.1 1.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ALMT PF11744.3 KKK24193.1 - 0.37 9.4 1.7 0.52 8.9 1.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter IncA PF04156.9 KKK24193.1 - 0.41 10.2 23.0 0.99 8.9 3.9 3.2 2 1 1 3 3 3 0 IncA protein Prefoldin_2 PF01920.15 KKK24193.1 - 0.46 10.2 21.3 0.17 11.6 1.9 4.2 2 1 1 3 3 3 0 Prefoldin subunit CENP-F_leu_zip PF10473.4 KKK24193.1 - 0.61 9.9 20.7 2.9 7.7 2.0 3.4 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.1 KKK24193.1 - 1.4 7.7 11.0 2.8 6.8 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3552 PF12072.3 KKK24193.1 - 3.1 6.9 19.5 5.3 6.1 4.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Fez1 PF06818.10 KKK24193.1 - 3.2 7.7 24.1 0.61 10.0 9.8 2.6 2 1 1 3 3 3 0 Fez1 Fib_alpha PF08702.5 KKK24193.1 - 3.4 7.8 8.0 2.6 8.1 1.8 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family NAM-associated PF14303.1 KKK24193.1 - 4 7.7 8.8 1.1 9.5 0.1 2.5 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF972 PF06156.8 KKK24193.1 - 4.3 7.7 14.9 4.6 7.6 0.7 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF972) ISG65-75 PF11727.3 KKK24193.1 - 7.5 5.5 9.0 1.5 7.8 1.6 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein AAA_13 PF13166.1 KKK24193.1 - 7.7 4.8 12.6 1.4 7.2 2.6 1.8 1 1 1 2 2 2 0 AAA domain COG2 PF06148.6 KKK24193.1 - 8.8 6.2 16.0 0.68 9.7 2.1 2.9 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.2 KKK24193.1 - 9.2 6.1 22.2 4.5 7.1 12.8 2.2 2 0 0 2 2 2 0 Tropomyosin like Syntaphilin PF15290.1 KKK24193.1 - 9.5 5.6 14.4 0.21 11.0 5.5 1.5 2 0 0 2 2 1 0 Golgi-localised syntaxin-1-binding clamp Ribosomal_S4 PF00163.14 KKK24194.1 - 1.5e-30 105.3 1.0 3e-30 104.4 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KKK24194.1 - 5.6e-13 48.0 1.0 5.6e-13 48.0 0.7 2.2 3 0 0 3 3 3 1 S4 domain Zn_clus PF00172.13 KKK24195.1 - 8.6e-06 25.5 8.2 1.6e-05 24.7 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_6 PF13921.1 KKK24196.1 - 3.5e-16 59.0 0.1 4.5e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK24196.1 - 2e-11 43.7 0.4 3.6e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Phosphoprotein PF00922.12 KKK24196.1 - 0.4 9.8 4.3 0.91 8.6 3.0 1.6 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein KH_dom-like PF14714.1 KKK24197.1 - 0.05 13.5 0.2 0.32 10.9 0.1 2.0 1 1 1 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Aldedh PF00171.17 KKK24198.1 - 6e-154 512.7 0.2 6.8e-154 512.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 KKK24198.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase Gln-synt_C PF00120.19 KKK24199.1 - 6.7e-44 149.9 0.0 1.5e-43 148.7 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 KKK24199.1 - 1.5e-33 116.5 0.0 3e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Annexin PF00191.15 KKK24200.1 - 1.6e-15 56.7 4.2 1e-05 25.3 0.1 4.4 4 0 0 4 4 4 4 Annexin PAT1 PF09770.4 KKK24200.1 - 0.0098 14.1 16.0 0.015 13.6 11.1 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF1793 PF08760.6 KKK24201.1 - 3.6e-66 222.2 0.5 9e-66 220.9 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF946 PF06101.6 KKK24202.1 - 7.7e-11 40.6 1.3 1.2e-10 40.0 0.3 1.9 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) NPP1 PF05630.6 KKK24202.1 - 0.0074 16.0 1.4 0.011 15.4 0.9 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Septin PF00735.13 KKK24203.1 - 4.2e-33 114.5 0.0 3.3e-13 49.2 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 KKK24203.1 - 0.00097 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 KKK24203.1 - 0.012 16.1 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KKK24203.1 - 0.012 15.4 1.8 0.022 14.6 0.0 2.4 3 1 0 3 3 3 0 Dynamin family MMR_HSR1 PF01926.18 KKK24203.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 KKK24203.1 - 0.069 13.1 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 KKK24203.1 - 0.25 9.9 0.0 0.25 9.9 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit Pkinase PF00069.20 KKK24204.1 - 2.5e-24 85.8 0.0 7.6e-24 84.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24204.1 - 1.2e-09 37.5 0.0 0.00062 18.9 0.0 3.3 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 KKK24204.1 - 0.035 13.8 0.1 0.56 9.8 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family DOPA_dioxygen PF08883.6 KKK24205.1 - 6.3e-31 106.5 0.0 8e-31 106.2 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family RRM_1 PF00076.17 KKK24206.1 - 2.7e-15 55.7 0.0 4.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK24206.1 - 2.2e-12 46.7 0.0 3.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK24206.1 - 1.9e-05 24.3 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KKK24206.1 - 0.0001 22.7 1.5 0.0001 22.7 1.0 2.9 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 HSP33 PF01430.14 KKK24206.1 - 0.053 12.6 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein Snf7 PF03357.16 KKK24207.1 - 4.5e-20 71.7 14.3 4.5e-20 71.7 9.9 1.8 1 1 1 2 2 2 1 Snf7 PSD4 PF07631.6 KKK24207.1 - 0.026 14.8 0.7 0.28 11.5 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1592) MerR-DNA-bind PF09278.6 KKK24207.1 - 0.87 10.0 16.9 3.7 8.0 0.1 4.6 4 1 1 5 5 5 0 MerR, DNA binding DUF4404 PF14357.1 KKK24207.1 - 3.1 8.2 18.5 5.9 7.3 0.3 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) CS PF04969.11 KKK24208.1 - 1.1e-09 38.6 0.0 1.9e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 CS domain adh_short PF00106.20 KKK24213.1 - 6.8e-14 52.1 0.0 7.5e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK24213.1 - 5.1e-07 29.5 0.0 5.6e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK24213.1 - 2.6e-06 27.3 0.0 3e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KKK24213.1 - 0.0074 15.2 0.0 0.0084 15.0 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KKK24213.1 - 0.041 12.5 0.0 0.05 12.3 0.0 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KKK24213.1 - 0.043 12.8 0.0 0.044 12.7 0.0 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 KKK24213.1 - 0.12 11.6 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.16 KKK24213.1 - 0.13 11.6 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_2 PF00891.13 KKK24214.1 - 8e-31 107.0 0.1 1.1e-30 106.6 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KKK24214.1 - 0.0002 21.8 0.0 0.00049 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK24214.1 - 0.00028 20.5 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_AsnC-type PF13404.1 KKK24214.1 - 0.00069 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MTS PF05175.9 KKK24214.1 - 0.0017 17.7 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KKK24214.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HTH_28 PF13518.1 KKK24214.1 - 0.06 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 KKK24214.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_lysozyme PF00959.14 KKK24214.1 - 0.13 12.5 0.1 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Phage lysozyme IDO PF01231.13 KKK24215.1 - 1.1e-172 574.2 0.0 1.2e-172 574.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aminotran_5 PF00266.14 KKK24216.1 - 6.3e-43 146.9 0.0 7.3e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Amidase PF01425.16 KKK24218.1 - 2.8e-93 313.2 0.0 3.3e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF1815 PF08844.5 KKK24218.1 - 0.072 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Arylsulfotran_2 PF14269.1 KKK24219.1 - 4.3e-43 147.5 0.1 6.4e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KKK24219.1 - 1.1e-13 50.5 0.2 2.3e-12 46.1 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Methyltransf_28 PF02636.12 KKK24220.1 - 1.7e-37 129.1 0.0 2.3e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Scm3 PF10384.4 KKK24221.1 - 4.7e-24 83.6 0.2 9.3e-24 82.6 0.2 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-binding PF00249.26 KKK24221.1 - 3.8e-06 26.8 0.8 0.02 14.9 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK24221.1 - 5.2e-06 26.4 2.6 0.0056 16.7 0.2 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain PALP PF00291.20 KKK24222.1 - 3.6e-41 141.3 0.1 4.9e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme rve PF00665.21 KKK24222.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain APG6 PF04111.7 KKK24223.1 - 1.1e-126 422.1 0.0 1.6e-126 421.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 RNase_P_p30 PF01876.11 KKK24224.1 - 3.9e-47 159.2 0.0 5.4e-47 158.7 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Brix PF04427.13 KKK24225.1 - 2.3e-33 115.4 0.0 2.9e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.14 KKK24226.1 - 2e-25 89.2 0.4 2e-25 89.2 0.3 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF2207 PF09972.4 KKK24226.1 - 0.071 11.6 0.3 0.072 11.6 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.20 KKK24227.1 - 1.6e-60 204.4 0.0 1.9e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24227.1 - 4.5e-20 71.8 0.0 6.3e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK24227.1 - 2.5e-08 33.9 0.4 9.7e-05 22.2 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK24227.1 - 0.0075 15.8 0.0 0.015 14.8 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KKK24227.1 - 0.021 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KKK24227.1 - 0.032 13.2 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KKK24227.1 - 0.062 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family tRNA-synt_1 PF00133.17 KKK24228.1 - 8.8e-219 727.4 0.0 4.4e-218 725.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KKK24228.1 - 8.8e-34 116.4 1.0 8.8e-34 116.4 0.7 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KKK24228.1 - 1.8e-15 56.5 0.3 2.9e-06 26.2 0.0 5.3 4 2 1 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KKK24228.1 - 1.3e-08 34.3 0.0 4.2e-05 22.9 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KKK24228.1 - 0.03 13.4 0.0 0.19 10.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain HR1 PF02185.11 KKK24228.1 - 9.3 6.0 11.8 0.054 13.2 1.7 2.1 2 0 0 2 2 2 0 Hr1 repeat Methyltransf_23 PF13489.1 KKK24229.1 - 2.1e-15 56.8 0.0 3.3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK24229.1 - 2.6e-06 27.9 0.1 9e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK24229.1 - 1.1e-05 25.7 0.0 3.3e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK24229.1 - 2.3e-05 24.7 0.0 0.00011 22.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK24229.1 - 7.5e-05 22.3 0.0 0.00019 21.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK24229.1 - 0.00017 21.0 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KKK24229.1 - 0.00018 21.5 0.0 0.00053 20.0 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KKK24229.1 - 0.0003 19.8 0.0 0.00069 18.7 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KKK24229.1 - 0.0038 17.2 0.1 0.0075 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK24229.1 - 0.011 16.0 0.1 0.08 13.3 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 KKK24229.1 - 0.042 12.9 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KKK24229.1 - 0.05 12.7 0.0 0.39 9.7 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KKK24229.1 - 0.074 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 KKK24229.1 - 0.077 12.1 0.1 0.76 8.9 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase p450 PF00067.17 KKK24230.1 - 3.3e-51 174.2 0.0 4.4e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 KKK24231.1 - 8.1e-11 41.8 0.2 1.3e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK24231.1 - 2.9e-10 40.1 0.5 3.2e-09 36.8 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KKK24231.1 - 0.0015 18.4 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK24231.1 - 0.0037 17.0 0.1 0.0078 15.9 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KKK24231.1 - 0.03 14.1 0.8 0.11 12.4 0.5 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2422 PF10337.4 KKK24232.1 - 1.3e-110 370.3 4.1 1.3e-110 370.3 2.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KKK24232.1 - 1.7e-64 217.5 0.0 2.4e-62 210.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KKK24232.1 - 2.8e-09 36.9 15.1 2.8e-09 36.9 10.5 3.8 3 2 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 KKK24232.1 - 1.4e-05 23.9 4.2 1.4e-05 23.9 2.9 1.8 2 0 0 2 2 2 1 Aluminium activated malate transporter PET122 PF05476.6 KKK24232.1 - 0.1 11.8 0.1 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 PET122 DUF3592 PF12158.3 KKK24232.1 - 5.6 6.7 6.2 0.57 9.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) HERV-K_env_2 PF13804.1 KKK24233.1 - 0.097 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein Fungal_trans PF04082.13 KKK24234.1 - 9.1e-09 34.5 1.5 1.5e-08 33.8 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MARVEL PF01284.18 KKK24235.1 - 0.00025 20.8 0.7 0.0034 17.2 0.1 2.4 2 0 0 2 2 2 1 Membrane-associating domain Sugar_tr PF00083.19 KKK24236.1 - 1.1e-76 258.2 18.7 1.4e-76 257.9 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24236.1 - 3e-30 105.1 21.1 5.2e-28 97.7 7.7 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinocilin PF15033.1 KKK24236.1 - 0.3 10.5 2.6 0.75 9.3 1.8 1.6 1 0 0 1 1 1 0 Kinocilin protein Glyco_hydro_28 PF00295.12 KKK24237.1 - 5.8e-85 285.1 18.5 5.8e-85 285.1 12.8 2.6 3 1 0 3 3 3 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 KKK24237.1 - 5.7e-34 117.0 3.0 2.4e-33 114.9 1.2 2.3 2 0 0 2 2 2 1 Pectinesterase Aa_trans PF01490.13 KKK24238.1 - 3.3e-24 85.1 24.8 6.7e-24 84.1 17.2 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_43 PF04616.9 KKK24239.1 - 4.9e-103 344.1 0.6 1.7e-102 342.4 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Ribonuclease PF00545.15 KKK24240.1 - 9.7e-17 60.8 0.5 1.3e-16 60.4 0.3 1.2 1 0 0 1 1 1 1 ribonuclease Aconitase PF00330.15 KKK24241.1 - 2.2e-62 211.0 0.0 1.7e-40 138.9 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KKK24241.1 - 1.9e-17 63.6 0.0 3.5e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MmgE_PrpD PF03972.9 KKK24242.1 - 1.2e-66 224.7 0.0 1.5e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MFS_1 PF07690.11 KKK24243.1 - 1.1e-19 70.4 56.0 1.6e-10 40.2 25.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2976 PF11190.3 KKK24243.1 - 8.3 6.0 17.0 6.5 6.3 1.8 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) ABC_tran PF00005.22 KKK24244.1 - 2.7e-49 166.9 0.0 1.4e-27 96.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK24244.1 - 5.3e-46 157.2 40.6 1.5e-26 93.4 14.4 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 KKK24244.1 - 3e-10 40.5 0.4 0.14 12.1 0.1 4.2 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KKK24244.1 - 4.6e-07 29.2 0.9 0.021 14.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KKK24244.1 - 8.1e-07 28.4 0.8 0.45 9.7 0.0 3.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KKK24244.1 - 8.2e-07 28.9 0.1 0.04 13.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KKK24244.1 - 2.9e-06 28.0 0.0 0.033 14.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KKK24244.1 - 7.6e-06 26.4 0.1 0.25 11.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 KKK24244.1 - 9.1e-06 26.1 0.1 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KKK24244.1 - 9.4e-06 24.8 0.0 0.024 13.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 KKK24244.1 - 1.8e-05 24.7 5.0 0.04 13.8 0.2 3.4 3 1 0 3 3 3 2 AAA ATPase domain Dynamin_N PF00350.18 KKK24244.1 - 5.5e-05 23.0 1.2 0.0079 16.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 KKK24244.1 - 0.00013 21.2 1.0 0.054 12.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK24244.1 - 0.00054 20.0 0.5 0.93 9.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KKK24244.1 - 0.0032 16.9 0.0 0.51 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 KKK24244.1 - 0.0034 16.8 0.1 0.69 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KKK24244.1 - 0.0079 16.0 0.6 0.21 11.3 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 KKK24244.1 - 0.011 16.0 0.8 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KKK24244.1 - 0.016 14.8 0.3 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KKK24244.1 - 0.025 14.1 1.0 3.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 KKK24244.1 - 0.029 14.0 0.2 4 7.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KKK24244.1 - 0.033 14.3 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KKK24244.1 - 0.034 13.6 0.2 3 7.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.9 KKK24244.1 - 0.11 12.2 0.1 18 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 KKK24244.1 - 0.11 11.5 0.0 13 4.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 KKK24244.1 - 0.12 11.0 1.3 3.5 6.3 0.3 2.3 2 0 0 2 2 2 0 ArgK protein AAA_PrkA PF08298.6 KKK24244.1 - 0.16 10.6 0.1 0.78 8.3 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain AAA_28 PF13521.1 KKK24244.1 - 0.17 11.8 1.2 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Phosphoesterase PF04185.9 KKK24245.1 - 4e-62 210.5 0.3 7.6e-62 209.6 0.2 1.5 1 1 0 1 1 1 1 Phosphoesterase family DUF1761 PF08570.5 KKK24247.1 - 5.6e-24 84.5 3.5 6.3e-24 84.3 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) PhaG_MnhG_YufB PF03334.9 KKK24247.1 - 0.7 9.9 4.4 7.2 6.7 3.0 2.7 1 1 0 1 1 1 0 Na+/H+ antiporter subunit PRELI PF04707.9 KKK24248.1 - 6.8e-45 152.4 0.3 7.9e-45 152.2 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family Mycobact_memb PF05423.8 KKK24248.1 - 0.052 13.2 0.1 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Mycobacterium membrane protein AhpC-TSA PF00578.16 KKK24249.1 - 1.1e-23 83.2 0.0 3.8e-23 81.4 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KKK24249.1 - 1.8e-12 46.9 0.0 2.8e-12 46.4 0.0 1.3 1 1 0 1 1 1 1 Redoxin Flavoprotein PF02441.14 KKK24250.1 - 3.4e-40 136.7 0.1 4.5e-40 136.3 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.19 KKK24251.1 - 4e-15 55.5 0.0 6.9e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin JmjC PF02373.17 KKK24252.1 - 1.2e-08 35.2 0.3 1.8e-07 31.4 0.2 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 KKK24252.1 - 1.5e-08 34.6 9.3 1.5e-08 34.6 6.4 2.5 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 KKK24252.1 - 0.0084 15.5 0.0 0.027 13.9 0.0 1.8 2 0 0 2 2 2 1 Cupin domain UbiA PF01040.13 KKK24253.1 - 6.8e-34 117.2 19.0 9.1e-34 116.8 13.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosomal_L3 PF00297.17 KKK24254.1 - 3.8e-37 128.1 3.6 9e-36 123.6 2.5 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 CTP_transf_2 PF01467.21 KKK24256.1 - 3.2e-19 69.5 0.0 1.8e-16 60.5 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase Zip PF02535.17 KKK24257.1 - 0.049 12.6 0.2 0.061 12.3 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2207 PF09972.4 KKK24257.1 - 0.071 11.6 0.1 0.11 11.0 0.0 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Coa1 PF08695.5 KKK24258.1 - 1.7e-30 104.8 0.1 2.3e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4307 PF14155.1 KKK24258.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) IF-2B PF01008.12 KKK24259.1 - 3.1e-74 249.4 0.3 3.6e-74 249.2 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Nucleoporin_C PF03177.9 KKK24260.1 - 7.4e-132 440.8 8.7 9.7e-132 440.4 6.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KKK24260.1 - 1.5e-75 254.5 0.0 2.4e-75 253.8 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like BsuPI PF12690.2 KKK24260.1 - 0.0065 16.1 0.0 1.9 8.2 0.0 3.4 3 0 0 3 3 3 1 Intracellular proteinase inhibitor Acyl_transf_1 PF00698.16 KKK24261.1 - 1.5e-22 80.3 0.0 3e-16 59.6 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Oxidored_q6 PF01058.17 KKK24262.1 - 3.6e-22 78.3 0.0 5.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mpp10 PF04006.7 KKK24263.1 - 3.2e-88 296.6 52.5 2.4e-86 290.4 36.4 2.3 1 1 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.4 KKK24264.1 - 4.2e-49 166.3 0.0 5.8e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KKK24264.1 - 0.065 13.8 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KKK24264.1 - 0.094 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain AAA PF00004.24 KKK24303.1 - 1.4e-06 28.5 0.0 2.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK24303.1 - 0.0034 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KKK24303.1 - 0.0037 16.6 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK24303.1 - 0.0053 17.5 0.1 0.014 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK24303.1 - 0.006 16.5 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KKK24303.1 - 0.01 16.1 0.0 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KKK24303.1 - 0.015 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain BCS1_N PF08740.6 KKK24303.1 - 0.016 14.8 0.6 0.76 9.3 0.1 2.1 1 1 1 2 2 2 0 BCS1 N terminal Polyoma_lg_T_C PF06431.6 KKK24303.1 - 0.02 13.5 0.0 0.028 13.0 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus ABC_tran PF00005.22 KKK24303.1 - 0.027 14.7 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KKK24303.1 - 0.031 13.8 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KKK24303.1 - 0.036 13.9 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KKK24303.1 - 0.048 12.2 0.0 0.072 11.6 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RNA_helicase PF00910.17 KKK24303.1 - 0.077 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.7 KKK24303.1 - 0.087 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 KKK24303.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK24303.1 - 0.1 12.5 0.1 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 KKK24303.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus KaiC PF06745.8 KKK24303.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC Pkinase PF00069.20 KKK24304.1 - 8.7e-60 202.0 0.0 1.2e-38 132.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24304.1 - 6e-26 91.0 0.0 2.9e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KKK24304.1 - 2.3e-11 43.6 0.2 6.3e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Kinase-like PF14531.1 KKK24304.1 - 6.1e-08 31.9 0.4 1.6e-05 24.0 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KKK24304.1 - 2.7e-06 27.2 0.0 0.0045 16.7 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KKK24304.1 - 0.004 16.2 0.0 0.0078 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 KKK24304.1 - 0.0081 15.9 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KKK24304.1 - 0.011 16.0 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 KKK24304.1 - 0.054 13.5 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 KKK24304.1 - 0.055 12.3 0.1 0.15 10.8 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Macoilin PF09726.4 KKK24304.1 - 0.98 7.6 3.1 1.6 6.8 2.1 1.4 1 0 0 1 1 1 0 Transmembrane protein C2 PF00168.25 KKK24310.1 - 5.9e-09 35.6 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain DnaJ PF00226.26 KKK24315.1 - 6.6e-27 93.0 2.0 1.1e-26 92.3 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KKK24315.1 - 2.3e-17 62.7 14.1 3.9e-17 62.0 9.8 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KKK24315.1 - 3.4e-10 39.6 0.0 2e-09 37.2 0.0 2.3 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 KKK24315.1 - 0.053 13.2 5.1 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-CSL PF05207.8 KKK24315.1 - 0.15 11.5 3.9 1.2 8.7 0.5 2.4 2 0 0 2 2 2 0 CSL zinc finger GRP PF07172.6 KKK24315.1 - 3.8 8.0 8.8 15 6.1 6.1 2.0 1 1 0 1 1 1 0 Glycine rich protein family Malic_M PF03949.10 KKK24316.1 - 4.2e-86 288.6 0.0 5.5e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KKK24316.1 - 9.5e-47 158.9 0.0 2.2e-36 125.1 0.0 2.3 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain Tricorn_C1 PF14684.1 KKK24317.1 - 0.00055 19.7 0.2 0.0022 17.8 0.1 2.2 1 0 0 1 1 1 1 Tricorn protease C1 domain DUF4449 PF14613.1 KKK24317.1 - 0.00091 19.1 2.2 0.0012 18.7 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) FCD PF07729.7 KKK24317.1 - 0.026 14.8 0.7 0.026 14.8 0.5 3.3 2 1 2 4 4 4 0 FCD domain Pox_C4_C10 PF03336.8 KKK24317.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Rho_Binding PF08912.6 KKK24317.1 - 0.23 11.7 2.8 6.3 7.1 0.0 3.5 3 0 0 3 3 3 0 Rho Binding 3-HAO PF06052.7 KKK24319.1 - 5.8e-34 116.6 0.0 8.7e-34 116.1 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KKK24319.1 - 0.00062 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain zf-ribbon_3 PF13248.1 KKK24319.1 - 0.0035 16.4 1.1 2.3 7.5 0.1 2.6 2 0 0 2 2 2 2 zinc-ribbon domain Cupin_1 PF00190.17 KKK24319.1 - 0.03 13.7 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Cupin Nudix_N_2 PF14803.1 KKK24319.1 - 0.033 13.8 0.7 7.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Nudix N-terminal Plant_tran PF04827.9 KKK24319.1 - 0.051 12.9 0.1 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein DZR PF12773.2 KKK24319.1 - 0.1 12.4 4.0 0.094 12.5 1.3 2.0 2 1 0 2 2 2 0 Double zinc ribbon ADK_lid PF05191.9 KKK24319.1 - 0.4 10.3 3.3 11 5.7 0.1 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid TF_Zn_Ribbon PF08271.7 KKK24319.1 - 1.2 8.4 4.4 4.7 6.6 0.1 3.0 1 1 2 3 3 3 0 TFIIB zinc-binding RRN7 PF11781.3 KKK24319.1 - 4.3 6.9 6.3 19 4.8 0.1 2.8 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 RTC_insert PF05189.8 KKK24320.1 - 5.5e-31 106.6 0.0 1e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 KKK24320.1 - 2.5e-29 101.6 0.0 3.6e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Glyco_hydro_43 PF04616.9 KKK24321.1 - 4.3e-26 91.6 8.1 2.4e-18 66.2 1.3 2.8 2 2 0 2 2 2 2 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 KKK24322.1 - 5.8e-17 61.4 0.0 9.6e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24322.1 - 3.3e-06 26.8 13.5 7e-06 25.8 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2_3 PF14378.1 KKK24323.1 - 2.6e-21 75.9 8.2 1.1e-10 41.4 0.1 3.9 3 1 0 3 3 3 3 PAP2 superfamily PAP2 PF01569.16 KKK24323.1 - 0.53 9.9 8.1 0.048 13.3 1.3 2.2 2 1 0 3 3 3 0 PAP2 superfamily PWWP PF00855.12 KKK24324.1 - 6.8e-07 29.3 1.1 4.1e-06 26.8 0.1 2.9 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.6 KKK24324.1 - 0.0024 17.3 0.3 0.0055 16.1 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SpoIIE PF07228.7 KKK24325.1 - 1.6e-11 44.2 0.2 3.7e-10 39.8 0.1 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KKK24325.1 - 1.2e-09 37.9 0.1 2.1e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KKK24325.1 - 1e-07 31.6 0.0 0.0054 16.1 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C HSCB_C PF07743.8 KKK24326.1 - 2.2e-20 72.8 0.0 1.6e-19 70.1 0.0 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KKK24326.1 - 3.5e-09 36.2 0.1 6.8e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 KKK24327.1 - 3.8e-48 159.7 20.9 5.7e-09 35.5 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KKK24327.1 - 2.1e-15 55.6 4.8 3.6e-15 54.9 3.3 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like PRTP PF01366.13 KKK24327.1 - 0.18 9.7 0.6 0.26 9.2 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein SLAC1 PF03595.12 KKK24328.1 - 1.3e-82 277.0 35.3 1.5e-82 276.9 24.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel BTB PF00651.26 KKK24329.1 - 0.081 12.9 0.2 3.9 7.5 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain SnoaL_2 PF12680.2 KKK24330.1 - 4.2e-06 27.0 0.0 5.5e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 KKK24331.1 - 3.3e-28 98.4 27.8 4.4e-28 97.9 19.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.20 KKK24332.1 - 8.1e-36 123.4 0.0 5.8e-22 78.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24332.1 - 2e-13 49.9 0.0 2.8e-12 46.2 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK24332.1 - 0.006 15.5 0.0 1.5 7.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KKK24332.1 - 0.041 13.5 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family CAP_GLY PF01302.20 KKK24333.1 - 3.2e-16 58.7 0.9 6.7e-16 57.7 0.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain TMF_DNA_bd PF12329.3 KKK24333.1 - 0.00011 21.8 25.6 0.21 11.3 3.0 5.1 5 0 0 5 5 5 2 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 KKK24333.1 - 0.00098 17.7 10.6 0.0014 17.1 2.8 2.1 1 1 1 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 KKK24333.1 - 0.0057 15.8 3.3 4 6.5 0.3 3.1 2 1 1 3 3 3 1 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 KKK24333.1 - 0.013 15.4 9.3 0.81 9.7 1.7 3.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 KKK24333.1 - 0.02 15.1 9.9 1.1 9.5 0.2 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 KKK24333.1 - 0.022 14.3 36.1 0.044 13.3 8.3 3.3 2 1 1 3 3 3 0 IncA protein Gp58 PF07902.6 KKK24333.1 - 0.023 12.9 1.6 0.032 12.4 0.6 1.4 1 1 0 1 1 1 0 gp58-like protein Occludin_ELL PF07303.8 KKK24333.1 - 0.3 11.8 10.3 1.9 9.2 1.8 3.4 3 0 0 3 3 3 0 Occludin homology domain YajC PF02699.10 KKK24333.1 - 0.31 10.7 0.9 0.73 9.5 0.1 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit BLOC1_2 PF10046.4 KKK24333.1 - 0.63 10.2 11.2 0.19 11.9 0.9 3.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 KKK24333.1 - 0.79 7.8 21.0 0.0091 14.2 5.6 2.7 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Spc7 PF08317.6 KKK24333.1 - 0.88 8.1 19.9 1.8 7.1 2.9 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein PilJ PF13675.1 KKK24333.1 - 1.2 9.4 22.0 0.032 14.5 2.2 4.4 2 1 2 4 4 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF812 PF05667.6 KKK24333.1 - 2.1 6.7 14.0 2.7 6.4 7.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) SlyX PF04102.7 KKK24333.1 - 2.2 8.7 19.9 0.17 12.2 2.7 4.0 3 0 0 3 3 3 0 SlyX DUF745 PF05335.8 KKK24333.1 - 5 6.6 9.6 0.18 11.2 1.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF745) DUF16 PF01519.11 KKK24333.1 - 5.2 7.3 10.1 20 5.4 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function DUF16 V_ATPase_I PF01496.14 KKK24333.1 - 5.2 4.7 15.9 2.7 5.7 0.0 3.0 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family Mod_r PF07200.8 KKK24333.1 - 5.8 6.8 21.4 2.1 8.2 4.3 3.3 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Yip1 PF04893.12 KKK24334.1 - 2.1e-14 53.4 15.6 2.9e-14 52.9 10.8 1.3 1 0 0 1 1 1 1 Yip1 domain Mem_trans PF03547.13 KKK24334.1 - 0.041 12.1 0.4 0.11 10.8 0.3 1.8 1 1 0 1 1 1 0 Membrane transport protein Fcf1 PF04900.7 KKK24338.1 - 2.5e-37 127.0 2.2 4.8e-36 122.8 0.1 2.1 2 0 0 2 2 2 2 Fcf1 DAO PF01266.19 KKK24339.1 - 6.6e-19 68.0 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Sugar_tr PF00083.19 KKK24340.1 - 4.5e-101 338.6 21.7 5.4e-101 338.3 15.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24340.1 - 8.1e-19 67.5 36.4 1.6e-15 56.6 11.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 KKK24341.1 - 4e-06 26.6 10.6 9.4e-06 25.4 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain K1 PF02960.9 KKK24342.1 - 0.015 15.3 0.1 0.035 14.1 0.0 1.6 1 1 0 1 1 1 0 K1 glycoprotein DUF3098 PF11297.3 KKK24342.1 - 0.078 12.7 0.4 0.078 12.7 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) PqiA PF04403.8 KKK24342.1 - 2.5 7.6 12.0 0.43 10.1 1.0 3.2 2 1 1 3 3 3 0 Paraquat-inducible protein A Vma12 PF11712.3 KKK24342.1 - 3.9 7.1 6.0 0.45 10.2 0.6 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase GFO_IDH_MocA PF01408.17 KKK24343.1 - 6e-26 91.3 0.9 7.4e-25 87.8 0.2 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KKK24343.1 - 8.9e-05 22.8 0.1 0.00026 21.3 0.1 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KKK24344.1 - 1.4e-19 70.7 0.0 2.5e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.19 KKK24345.1 - 9.1e-40 136.5 6.4 1.1e-39 136.2 4.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24345.1 - 1.5e-18 66.6 11.7 1.9e-18 66.3 8.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Mg_trans_NIPA PF05653.9 KKK24378.1 - 6.5e-58 196.0 3.2 2.1e-57 194.4 2.0 1.7 2 0 0 2 2 2 1 Magnesium transporter NIPA EmrE PF13536.1 KKK24378.1 - 0.0011 19.0 0.2 0.0011 19.0 0.1 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KKK24378.1 - 0.0014 18.6 2.0 0.0014 18.6 1.4 3.3 2 1 0 3 3 3 1 EamA-like transporter family BTP PF05232.7 KKK24378.1 - 5.5 6.7 7.0 9.9 5.9 0.4 2.6 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family DUF4131 PF13567.1 KKK24378.1 - 6.2 6.1 9.6 1.2 8.5 1.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) AAA PF00004.24 KKK24379.1 - 4.8e-41 140.0 0.0 9.2e-41 139.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK24379.1 - 1.3e-07 31.8 0.1 5.1e-05 23.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KKK24379.1 - 9.8e-06 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KKK24379.1 - 1.1e-05 24.4 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KKK24379.1 - 1.7e-05 24.5 0.0 5e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK24379.1 - 0.00019 21.4 0.1 0.0014 18.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KKK24379.1 - 0.0007 18.7 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KKK24379.1 - 0.0027 17.7 1.3 0.0041 17.1 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KKK24379.1 - 0.0027 17.6 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK24379.1 - 0.0059 17.4 1.1 0.013 16.3 0.1 2.2 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KKK24379.1 - 0.006 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KKK24379.1 - 0.0069 15.4 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KKK24379.1 - 0.007 16.0 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KKK24379.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KKK24379.1 - 0.012 14.8 0.8 0.21 10.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 KKK24379.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK24379.1 - 0.014 15.0 0.1 0.35 10.5 0.1 2.3 1 1 0 2 2 2 0 NACHT domain AAA_3 PF07726.6 KKK24379.1 - 0.014 14.9 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KKK24379.1 - 0.016 14.6 1.8 0.24 10.7 0.3 2.5 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 KKK24379.1 - 0.017 13.8 0.2 0.046 12.4 0.1 1.7 1 1 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 KKK24379.1 - 0.03 13.1 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 KKK24379.1 - 0.033 13.3 0.2 0.47 9.5 0.1 2.2 1 1 0 2 2 2 0 KaiC RNA_helicase PF00910.17 KKK24379.1 - 0.038 14.1 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KKK24379.1 - 0.047 13.2 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK24379.1 - 0.053 12.6 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KKK24379.1 - 0.13 11.1 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2985 PF11204.3 KKK24380.1 - 7e-29 99.4 3.9 7e-29 99.4 2.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Peptidase_S49_N PF08496.5 KKK24380.1 - 0.05 13.3 0.9 0.11 12.3 0.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med30 PF11315.3 KKK24381.1 - 0.06 13.4 0.1 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 30 Rootletin PF15035.1 KKK24381.1 - 0.18 11.7 10.7 0.26 11.2 1.9 2.6 2 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.13 KKK24381.1 - 0.37 10.5 4.5 1.7 8.3 0.7 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 KKK24381.1 - 0.43 10.9 2.2 28 5.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Glyco_hydro_3 PF00933.16 KKK24382.1 - 7.6e-69 231.9 0.0 9.9e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK24382.1 - 1e-61 208.3 0.0 1.6e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK24382.1 - 8.7e-21 73.6 1.2 8.7e-21 73.6 0.8 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 KKK24382.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain ArfGap PF01412.13 KKK24383.1 - 3.8e-31 107.3 0.0 6.7e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Epimerase PF01370.16 KKK24384.1 - 1.9e-12 47.1 0.1 2.9e-06 26.8 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KKK24384.1 - 1.4e-08 34.3 0.1 1.9e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KKK24384.1 - 1.1e-06 28.9 0.1 1.7e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KKK24384.1 - 5.6e-05 23.2 0.1 9.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KKK24384.1 - 0.00018 20.5 0.0 0.0011 17.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KKK24384.1 - 0.00018 20.2 0.0 0.0016 17.2 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KKK24384.1 - 0.0023 16.9 0.1 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KKK24384.1 - 0.0025 16.7 0.1 0.0035 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KKK24384.1 - 0.02 15.0 0.0 0.14 12.2 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Tho2 PF11262.3 KKK24385.1 - 1.7e-94 316.2 0.0 2.7e-94 315.5 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KKK24385.1 - 2e-14 53.1 0.5 9.7e-14 50.9 0.1 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Ant_C PF05586.6 KKK24385.1 - 0.032 14.6 0.1 2.4 8.6 0.0 2.9 2 0 0 2 2 2 0 Anthrax receptor C-terminus region WD40 PF00400.27 KKK24386.1 - 1.4e-20 72.2 17.2 3.9e-07 29.7 0.9 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat TFIIF_alpha PF05793.7 KKK24386.1 - 0.27 9.5 14.7 0.42 8.9 10.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 KKK24386.1 - 1.5 8.1 9.9 3.7 6.8 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 KKK24386.1 - 2.6 5.9 9.9 3.9 5.3 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein UQ_con PF00179.21 KKK24387.1 - 3.2e-43 146.5 0.0 4.1e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KKK24387.1 - 1.6e-07 30.8 1.2 3.2e-06 26.6 0.0 2.3 1 1 1 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KKK24387.1 - 0.00027 20.7 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KKK24387.1 - 0.017 15.0 0.8 0.035 14.0 0.5 1.7 1 1 0 1 1 1 0 RWD domain RRM_1 PF00076.17 KKK24388.1 - 2e-30 104.1 0.1 5.5e-15 54.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK24388.1 - 2.5e-21 75.4 0.0 7.7e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK24388.1 - 3e-07 30.1 0.0 0.032 14.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 KKK24388.1 - 0.084 11.3 2.9 0.11 10.9 2.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Cyclin_N PF00134.18 KKK24389.1 - 1.2e-07 31.3 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain GTP_EFTU PF00009.22 KKK24390.1 - 9.8e-55 184.9 0.0 1.4e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KKK24390.1 - 1.8e-25 88.5 0.0 4.1e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KKK24390.1 - 1.8e-16 59.7 0.0 5.2e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KKK24390.1 - 5.5e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KKK24390.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EFG_IV PF03764.13 KKK24390.1 - 0.083 12.4 0.1 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Elongation factor G, domain IV FTHFS PF01268.14 KKK24390.1 - 0.28 9.1 0.0 0.41 8.5 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DUF3446 PF11928.3 KKK24390.1 - 0.54 10.4 11.5 0.048 13.8 3.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Vps5 PF09325.5 KKK24391.1 - 3.5e-16 59.1 1.5 5.2e-16 58.6 1.1 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KKK24391.1 - 3e-09 36.6 0.0 6.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 PX domain GRAM PF02893.15 KKK24392.1 - 2.2e-17 62.3 0.0 5.4e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 GRAM domain RNB PF00773.14 KKK24403.1 - 4.8e-81 272.5 0.0 5.2e-80 269.1 0.0 2.2 2 0 0 2 2 2 1 RNB domain GLE1 PF07817.8 KKK24404.1 - 3.6e-15 55.6 2.2 9.7e-14 50.9 0.0 3.2 2 2 1 3 3 3 2 GLE1-like protein Borrelia_P83 PF05262.6 KKK24404.1 - 7 4.7 40.4 10 4.2 28.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2962 PF11176.3 KKK24407.1 - 1.8e-53 180.2 0.0 4.1e-53 179.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) MAM33 PF02330.11 KKK24407.1 - 1e-35 123.4 2.6 7.7e-35 120.5 1.8 2.1 1 1 0 1 1 1 1 Mitochondrial glycoprotein NPV_P10 PF05531.7 KKK24407.1 - 0.083 13.1 0.2 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein XPG_I PF00867.13 KKK24408.1 - 8.8e-27 93.0 0.3 2.2e-26 91.7 0.1 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KKK24408.1 - 1.8e-23 82.6 0.0 4.7e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KKK24408.1 - 0.00034 20.1 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing HTH_13 PF11972.3 KKK24408.1 - 0.13 12.1 0.3 4.5 7.1 0.0 2.7 3 0 0 3 3 3 0 HTH DNA binding domain TPR_2 PF07719.12 KKK24408.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 KKK24408.1 - 0.14 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 TPR repeat Fig1 PF12351.3 KKK24409.1 - 5e-45 153.6 13.6 1.2e-30 106.8 0.0 3.0 2 1 1 3 3 3 3 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KKK24409.1 - 0.004 16.7 14.3 0.4 10.2 9.9 2.5 1 1 0 1 1 1 1 SUR7/PalI family SAM_adeno_trans PF01887.11 KKK24409.1 - 0.065 12.2 0.1 0.094 11.7 0.1 1.1 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase COesterase PF00135.23 KKK24410.1 - 4.2e-82 276.5 0.0 1e-81 275.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK24410.1 - 2e-11 43.8 0.0 6.3e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK24410.1 - 0.00039 20.1 0.1 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK24410.1 - 0.055 12.6 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DNA_primase_S PF01896.14 KKK24411.1 - 1.3e-53 180.7 0.0 2.3e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Ras PF00071.17 KKK24436.1 - 1.4e-59 200.0 0.2 1.7e-59 199.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK24436.1 - 7.2e-19 68.4 0.0 1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK24436.1 - 1.3e-08 34.3 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK24436.1 - 1.2e-07 31.4 0.1 5.6e-07 29.1 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KKK24436.1 - 0.0017 17.6 0.0 0.0027 16.9 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KKK24436.1 - 0.0021 17.9 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2075 PF09848.4 KKK24436.1 - 0.028 13.3 0.1 0.64 8.9 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Gtr1_RagA PF04670.7 KKK24436.1 - 0.033 13.3 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 KKK24436.1 - 0.053 12.9 0.6 0.72 9.2 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 KKK24436.1 - 0.064 12.4 0.1 0.21 10.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF2277 PF10041.4 KKK24436.1 - 0.11 12.4 0.0 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) ATP_bind_1 PF03029.12 KKK24436.1 - 0.15 11.5 1.7 1.9 7.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CbiA PF01656.18 KKK24436.1 - 0.15 11.4 0.1 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain GshA PF08886.6 KKK24437.1 - 0.12 10.6 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase WD40 PF00400.27 KKK24438.1 - 3.1e-07 30.0 6.5 0.33 10.8 0.0 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat Lactonase PF10282.4 KKK24438.1 - 0.047 12.7 0.0 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Nucleoporin_FG PF13634.1 KKK24440.1 - 2.8e-09 37.2 105.5 3.8e-07 30.3 37.7 3.4 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF1664 PF07889.7 KKK24440.1 - 0.016 14.9 0.2 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PEMT PF04191.8 KKK24449.1 - 5.5e-54 180.7 17.2 5.8e-35 119.5 1.0 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase RNase_PH PF01138.16 KKK24450.1 - 3.3e-32 111.5 0.0 7e-32 110.5 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 PRT_C PF08372.5 KKK24450.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal HTH_AsnC-type PF13404.1 KKK24451.1 - 0.043 13.3 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HAD_2 PF13419.1 KKK24452.1 - 3.4e-11 43.6 0.0 0.00042 20.5 0.0 2.9 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK24452.1 - 0.0017 18.0 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NAD_binding_4 PF07993.7 KKK24453.1 - 2.9e-33 114.8 0.0 4.1e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KKK24453.1 - 8e-06 24.7 0.0 7.9e-05 21.4 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KKK24453.1 - 0.00019 21.4 0.0 0.00044 20.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KKK24453.1 - 0.00021 20.7 0.0 0.00056 19.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK24453.1 - 0.0034 17.0 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1413 PF07205.6 KKK24453.1 - 0.12 11.9 0.1 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) SR-25 PF10500.4 KKK24454.1 - 0.00098 18.6 7.4 0.00098 18.6 5.1 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 KKK24454.1 - 0.025 12.6 3.6 0.028 12.4 2.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2217 PF10265.4 KKK24454.1 - 0.051 12.3 1.3 0.071 11.8 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Hid1 PF12722.2 KKK24454.1 - 0.22 9.1 1.7 0.28 8.8 1.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-U PF13097.1 KKK24454.1 - 0.25 11.2 6.0 0.42 10.5 4.2 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit BUD22 PF09073.5 KKK24454.1 - 0.4 9.7 9.2 0.55 9.2 6.4 1.2 1 0 0 1 1 1 0 BUD22 DUF4614 PF15391.1 KKK24454.1 - 3.2 7.4 11.1 0.46 10.2 4.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) GET2 PF08690.5 KKK24455.1 - 7.9e-07 28.6 0.0 1.7e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 SOG2 PF10428.4 KKK24455.1 - 0.25 9.9 4.6 0.32 9.6 3.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein C2 PF00168.25 KKK24456.1 - 1.6e-20 72.7 0.0 6.4e-15 54.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain PIG-L PF02585.12 KKK24457.1 - 4.8e-14 52.9 0.1 1.3e-13 51.6 0.0 1.6 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase APH PF01636.18 KKK24458.1 - 7.7e-13 48.7 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sugar_tr PF00083.19 KKK24459.1 - 4.4e-79 266.1 22.7 5.1e-79 265.9 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24459.1 - 4.3e-15 55.2 58.3 1.9e-13 49.8 24.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KKK24459.1 - 7.3e-10 37.8 27.1 4.3e-05 22.0 1.2 4.3 3 2 1 4 4 4 4 MFS/sugar transport protein DUF3006 PF11213.3 KKK24459.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) zf-C2H2_2 PF12756.2 KKK24460.1 - 0.0053 16.8 0.2 0.015 15.4 0.2 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KKK24460.1 - 0.011 15.7 1.7 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KKK24460.1 - 0.012 15.9 4.6 0.19 12.1 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK24460.1 - 0.016 15.4 2.0 0.95 9.9 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type DZR PF12773.2 KKK24460.1 - 0.023 14.4 0.1 0.051 13.4 0.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon EntA_Immun PF08951.5 KKK24461.1 - 0.0087 16.1 0.0 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 Enterocin A Immunity DASH_Duo1 PF08651.5 KKK24470.1 - 8.4e-31 105.3 3.1 8.4e-31 105.3 2.1 1.8 2 0 0 2 2 2 1 DASH complex subunit Duo1 Tic20 PF09685.5 KKK24470.1 - 2.7e-07 30.5 1.8 4.2e-07 29.9 1.3 1.3 1 0 0 1 1 1 1 Tic20-like protein DUF745 PF05335.8 KKK24470.1 - 0.0095 15.4 11.0 0.014 14.9 7.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF4557 PF15101.1 KKK24470.1 - 0.62 9.8 5.6 1.3 8.8 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RNase_H2-Ydr279 PF09468.5 KKK24471.1 - 3.1e-101 338.5 2.0 4e-101 338.2 1.4 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) zf-primase PF09329.6 KKK24472.1 - 2.2e-19 68.7 0.7 3.7e-19 68.0 0.5 1.4 1 0 0 1 1 1 1 Primase zinc finger Fungal_trans PF04082.13 KKK24473.1 - 1.2e-20 73.4 0.0 2.4e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain GPI2 PF06432.6 KKK24474.1 - 1.8e-116 388.4 0.9 2.3e-116 388.0 0.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Glyco_hydro_18 PF00704.23 KKK24475.1 - 2.2e-50 172.0 0.9 1.5e-49 169.3 0.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KKK24475.1 - 2.7e-06 27.2 21.5 5.7e-06 26.2 14.9 1.5 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_66 PF13199.1 KKK24475.1 - 0.027 12.9 0.0 0.043 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Iso_dh PF00180.15 KKK24476.1 - 7.4e-88 294.8 0.0 8.3e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IU_nuc_hydro PF01156.14 KKK24476.1 - 0.056 12.6 0.1 0.099 11.8 0.1 1.4 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase DUF1400 PF07176.6 KKK24476.1 - 0.071 13.0 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) PdxA PF04166.7 KKK24476.1 - 0.093 11.9 0.1 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthetic protein PdxA LrgA PF03788.9 KKK24477.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 LrgA family Cofilin_ADF PF00241.15 KKK24478.1 - 4.2e-11 42.8 0.0 5.1e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1344 PF07076.6 KKK24478.1 - 0.13 11.8 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) TPP_enzyme_N PF02776.13 KKK24479.1 - 1.4e-34 119.0 0.0 3.1e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KKK24479.1 - 1e-15 57.6 0.0 2.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KKK24479.1 - 6.1e-15 55.1 0.0 2.9e-14 52.9 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glycos_transf_1 PF00534.15 KKK24480.1 - 5.9e-15 55.0 0.0 9.7e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KKK24480.1 - 0.0001 22.4 0.0 0.00023 21.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KKK24480.1 - 0.14 12.3 0.1 1.9 8.8 0.1 2.4 1 1 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_11 PF08241.7 KKK24481.1 - 5.6e-23 81.2 0.0 1.9e-22 79.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK24481.1 - 1.3e-17 63.8 0.0 2.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK24481.1 - 1.5e-14 54.0 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK24481.1 - 2.4e-13 50.3 0.0 5.7e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK24481.1 - 3.3e-12 46.7 0.0 9.7e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK24481.1 - 5.1e-11 42.1 0.0 7.9e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KKK24481.1 - 3.4e-10 39.4 0.0 4.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KKK24481.1 - 4.8e-10 39.4 0.1 3.8e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK24481.1 - 7.5e-10 39.3 0.0 1.5e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KKK24481.1 - 8.7e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 KKK24481.1 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KKK24481.1 - 0.0024 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KKK24481.1 - 0.0041 16.1 0.0 0.019 13.9 0.0 1.9 1 1 1 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.15 KKK24481.1 - 0.007 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 KKK24481.1 - 0.0076 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 KKK24481.1 - 0.0086 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 KKK24481.1 - 0.0099 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 KKK24481.1 - 0.019 14.6 0.0 0.32 10.5 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase TehB PF03848.9 KKK24481.1 - 0.023 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Sugar_tr PF00083.19 KKK24483.1 - 5.1e-41 140.7 18.2 2.4e-29 102.2 2.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK24483.1 - 5.2e-25 87.9 23.1 5.2e-25 87.9 16.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KKK24483.1 - 3e-07 29.3 17.9 0.00023 19.8 2.4 3.0 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 KKK24483.1 - 4.5e-06 25.3 1.6 4.5e-06 25.3 1.1 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2516 PF10724.4 KKK24483.1 - 0.027 14.4 1.9 1.3 9.0 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) Fe-ADH PF00465.14 KKK24490.1 - 3e-29 101.7 0.0 3.3e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase LSM PF01423.17 KKK24491.1 - 1.8e-18 65.8 0.0 2e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KKK24491.1 - 0.0019 18.0 0.1 0.0023 17.8 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain UnbV_ASPIC PF07593.7 KKK24491.1 - 0.041 13.5 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 ASPIC and UnbV Rad60-SLD PF11976.3 KKK24492.1 - 8.6e-21 73.4 0.0 1.2e-17 63.3 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KKK24492.1 - 0.003 16.9 0.0 0.28 10.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family His_Phos_2 PF00328.17 KKK24493.1 - 1.1e-118 396.5 0.7 1.7e-118 395.9 0.2 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KKK24493.1 - 7.2e-06 25.6 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain N-SET PF11764.3 KKK24494.1 - 3.2e-38 131.2 0.7 3.2e-38 131.2 0.5 2.8 3 1 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 KKK24494.1 - 5.9e-26 89.5 0.6 1.2e-25 88.6 0.4 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 KKK24494.1 - 1.6e-22 80.5 0.1 1.6e-22 80.5 0.1 3.2 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.17 KKK24494.1 - 5.5e-05 22.7 0.0 0.00016 21.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 KKK24495.1 - 2.5e-06 26.4 50.0 8.1e-05 21.4 28.6 4.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Pam17 PF08566.5 KKK24495.1 - 0.067 12.8 1.4 0.094 12.3 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Thioredoxin PF00085.15 KKK24520.1 - 3.1e-61 203.5 0.5 8.9e-31 105.6 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin MKT1_C PF12246.3 KKK24520.1 - 1.4e-55 187.9 0.0 6.5e-28 97.3 0.0 2.3 1 1 1 2 2 2 2 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KKK24520.1 - 2.2e-32 111.2 0.1 5.5e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication ERp29 PF07749.7 KKK24520.1 - 3.2e-21 75.7 0.7 1.2e-20 73.9 0.5 2.0 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KKK24520.1 - 7.5e-18 64.7 0.5 2.6e-07 30.8 0.0 3.6 4 0 0 4 4 3 2 Thioredoxin-like domain XPG_I PF00867.13 KKK24520.1 - 1.3e-15 57.2 0.0 5.1e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 XPG I-region Thioredoxin_7 PF13899.1 KKK24520.1 - 4.8e-13 48.9 0.0 1.4e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KKK24520.1 - 3.2e-12 46.3 0.3 0.00011 22.2 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 KKK24520.1 - 8.4e-07 28.7 0.1 0.05 13.2 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 KKK24520.1 - 8e-06 25.4 0.2 0.027 14.0 0.0 2.9 2 0 0 2 2 2 2 Redoxin XPG_N PF00752.12 KKK24520.1 - 3e-05 24.1 0.0 0.00011 22.4 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain Thioredoxin_9 PF14595.1 KKK24520.1 - 0.0061 16.1 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.6 KKK24520.1 - 0.085 12.7 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 KKK24520.1 - 0.18 11.7 5.2 8.3 6.3 0.0 4.0 3 2 2 5 5 5 0 Thioredoxin Laps PF10169.4 KKK24520.1 - 4.2 7.6 8.0 1.8 8.8 3.6 1.8 2 0 0 2 2 2 0 Learning-associated protein zf-MYND PF01753.13 KKK24521.1 - 2e-07 30.7 20.4 2e-07 30.7 14.2 1.7 2 0 0 2 2 2 1 MYND finger DIOX_N PF14226.1 KKK24522.1 - 2.5e-19 69.9 0.0 4.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK24522.1 - 2.4e-06 27.7 0.0 4.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3485 PF11984.3 KKK24522.1 - 0.18 10.8 1.9 1.1 8.3 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3485) HSBP1 PF06825.7 KKK24523.1 - 2.2e-18 65.5 0.0 2.9e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 KKK24523.1 - 3.4e-05 23.1 0.9 0.1 11.9 0.1 2.1 1 1 1 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin DUF2937 PF11157.3 KKK24523.1 - 0.0021 17.4 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) Baculo_PEP_C PF04513.7 KKK24523.1 - 0.013 15.3 0.1 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1932 PF09130.6 KKK24523.1 - 0.014 15.1 0.1 0.049 13.3 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1932) NPV_P10 PF05531.7 KKK24523.1 - 0.015 15.5 0.1 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.13 KKK24523.1 - 0.026 14.0 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SPX PF03105.14 KKK24523.1 - 0.029 14.1 0.0 0.032 14.0 0.0 1.0 1 0 0 1 1 1 0 SPX domain Corona_S2 PF01601.11 KKK24523.1 - 0.066 11.2 0.1 0.078 11.0 0.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF1664 PF07889.7 KKK24523.1 - 0.069 12.9 0.1 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PilJ PF13675.1 KKK24523.1 - 0.072 13.4 0.1 0.081 13.2 0.1 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Tup_N PF08581.5 KKK24523.1 - 0.082 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Tup N-terminal KfrA_N PF11740.3 KKK24523.1 - 0.12 12.8 0.5 0.16 12.3 0.1 1.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term UPF0184 PF03670.8 KKK24523.1 - 0.19 11.9 0.8 0.4 10.9 0.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF1771 PF08590.5 KKK24524.1 - 1.4e-25 89.0 8.2 5.2e-25 87.2 5.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KKK24524.1 - 1.4e-16 60.3 2.5 2e-16 59.9 0.2 2.3 2 1 1 3 3 3 1 Smr domain FAM60A PF15396.1 KKK24524.1 - 0.41 10.3 6.5 0.081 12.6 0.6 2.0 2 0 0 2 2 2 0 Protein Family FAM60A Med15 PF09606.5 KKK24524.1 - 0.91 7.6 25.0 1.4 7.0 17.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal OmpH PF03938.9 KKK24524.1 - 1.4 8.8 24.1 2.7 7.9 3.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ApoO PF09769.4 KKK24524.1 - 2.2 7.9 4.7 1.7 8.3 0.0 2.3 2 1 0 2 2 2 0 Apolipoprotein O Uds1 PF15456.1 KKK24524.1 - 4.9 7.1 9.2 9.9 6.1 1.2 2.8 3 1 0 3 3 3 0 Up-regulated During Septation FlaG PF03646.10 KKK24524.1 - 7 6.8 13.4 1.7 8.8 4.7 2.8 2 1 0 3 3 3 0 FlaG protein V-ATPase_G PF03179.10 KKK24524.1 - 7.9 6.8 13.1 2.5 8.4 1.5 3.1 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit CDC14 PF08045.6 KKK24525.1 - 4.5e-101 337.2 0.0 5.2e-101 337.1 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.12 KKK24526.1 - 2.2e-58 197.1 0.0 2.9e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Tom37_C PF11801.3 KKK24527.1 - 8.3e-06 25.7 0.4 0.00065 19.6 0.3 2.1 1 1 1 2 2 2 2 Tom37 C-terminal domain GST_C_2 PF13410.1 KKK24527.1 - 0.00012 21.9 0.4 0.00025 20.8 0.2 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF717 PF05338.7 KKK24527.1 - 0.059 13.3 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF717) FA_hydroxylase PF04116.8 KKK24529.1 - 2.5e-14 53.6 10.6 2.5e-14 53.6 7.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MscL PF01741.13 KKK24530.1 - 2.1e-14 53.7 1.0 4e-14 52.8 0.7 1.5 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL PyrI_C PF02748.10 KKK24530.1 - 0.14 11.5 0.3 0.33 10.4 0.1 1.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Glyco_hydro_2 PF00703.16 KKK24531.1 - 8e-12 45.5 0.1 2.2e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KKK24531.1 - 5.6e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF3344 PF11824.3 KKK24531.1 - 0.029 13.7 0.3 3.2 7.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3344) Glyco_hydro_2_C PF02836.12 KKK24531.1 - 0.082 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_76 PF03663.9 KKK24532.1 - 2.4e-152 507.6 23.3 3.7e-152 507.0 16.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ADH_N PF08240.7 KKK24532.1 - 3.3e-26 91.1 0.3 2.2e-25 88.5 0.1 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK24532.1 - 4e-22 78.1 3.8 1.8e-21 76.0 1.1 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK24532.1 - 4.2e-06 27.6 0.1 9.1e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box-like PF12937.2 KKK24533.1 - 0.0012 18.5 1.1 0.013 15.1 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK24533.1 - 0.0012 18.3 0.2 0.0041 16.7 0.1 1.9 1 0 0 1 1 1 1 F-box domain Sugar_tr PF00083.19 KKK24534.1 - 3.8e-133 444.3 22.4 4.4e-133 444.1 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24534.1 - 1.2e-21 76.8 37.1 1e-11 44.1 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.6 KKK24534.1 - 0.082 12.8 1.0 0.2 11.6 0.0 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF962) DUF3430 PF11912.3 KKK24535.1 - 0.033 13.9 0.0 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Cutinase PF01083.17 KKK24536.1 - 1.7e-42 145.2 0.3 2.3e-42 144.7 0.2 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 KKK24536.1 - 5.9e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KKK24536.1 - 0.00061 19.3 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KKK24536.1 - 0.0062 16.3 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK24536.1 - 0.015 15.2 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 KKK24536.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Lipase_3 PF01764.20 KKK24536.1 - 0.065 12.8 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Amidase PF01425.16 KKK24537.1 - 2.3e-84 283.7 0.0 3.8e-84 283.0 0.0 1.3 1 1 0 1 1 1 1 Amidase Glyco_hydro_3 PF00933.16 KKK24538.1 - 3.2e-93 311.9 0.0 4.6e-93 311.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK24538.1 - 3e-59 200.2 0.0 4.9e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK24538.1 - 5.9e-25 87.0 0.3 1.4e-24 85.7 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain p450 PF00067.17 KKK24539.1 - 5.2e-76 256.0 0.0 7.7e-76 255.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KKK24539.1 - 6.8e-12 44.8 0.3 1.2e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 KKK24541.1 - 3.3e-07 29.0 0.0 4e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_10 PF12846.2 KKK24542.1 - 1.2e-08 34.7 0.1 1.7e-08 34.3 0.1 1.3 1 1 0 1 1 1 1 AAA-like domain Zot PF05707.7 KKK24542.1 - 0.0026 17.2 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Na_Ca_ex PF01699.19 KKK24543.1 - 1.7e-37 128.1 22.9 1.9e-20 72.9 6.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Fungal_trans PF04082.13 KKK24544.1 - 2.5e-19 69.1 0.0 5.5e-19 68.0 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24544.1 - 4.4e-05 23.2 7.6 8.9e-05 22.3 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 KKK24545.1 - 3.6e-14 53.1 0.0 3.9e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK24545.1 - 0.046 13.6 0.2 0.061 13.2 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N PF00107.21 KKK24545.1 - 0.059 12.9 0.3 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Usp PF00582.21 KKK24550.1 - 6.9e-17 61.9 4.0 1.4e-15 57.6 0.7 3.0 2 1 0 2 2 2 1 Universal stress protein family ATP-synt_ab PF00006.20 KKK24551.1 - 4.8e-62 209.2 0.0 6.7e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KKK24551.1 - 5.7e-16 59.0 0.0 1.1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KKK24551.1 - 4.5e-11 42.8 0.3 9.3e-11 41.7 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KKK24551.1 - 0.00053 19.8 0.2 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain BSP_II PF05432.6 KKK24553.1 - 0.0013 18.0 8.8 0.0019 17.5 6.1 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 KKK24553.1 - 0.0027 16.9 3.1 0.0045 16.2 2.2 1.3 1 0 0 1 1 1 1 Myc amino-terminal region FAM176 PF14851.1 KKK24553.1 - 0.038 13.6 2.4 0.071 12.7 1.7 1.4 1 0 0 1 1 1 0 FAM176 family CAML PF14963.1 KKK24553.1 - 0.048 13.0 1.2 0.086 12.1 0.9 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand CENP-B_dimeris PF09026.5 KKK24553.1 - 0.7 10.1 10.0 1.4 9.1 6.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_RNA_Pol_19 PF05320.7 KKK24553.1 - 1.7 8.4 5.8 3 7.5 4.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Spt5_N PF11942.3 KKK24553.1 - 2 9.0 14.9 0.23 12.1 6.1 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NOA36 PF06524.7 KKK24553.1 - 3 7.0 5.1 4.7 6.3 3.5 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KKK24553.1 - 6 6.3 11.0 9.8 5.6 7.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Glyco_hyd_65N_2 PF14498.1 KKK24554.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain BCDHK_Adom3 PF10436.4 KKK24555.1 - 1.4e-70 236.0 0.0 2e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KKK24555.1 - 1e-13 50.9 0.0 2.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KKK24555.1 - 0.036 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 KKK24555.1 - 0.15 11.3 0.1 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family NUFIP1 PF10453.4 KKK24556.1 - 3.6e-19 68.0 2.2 3.6e-19 68.0 1.5 3.1 3 0 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 KKK24556.1 - 1.7e-07 30.7 2.4 3.1e-07 29.9 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ycf1 PF05758.7 KKK24556.1 - 9.4 3.7 12.1 15 3.1 8.4 1.3 1 0 0 1 1 1 0 Ycf1 RNA_pol_Rbc25 PF08292.7 KKK24557.1 - 5e-35 120.3 0.0 7.2e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KKK24557.1 - 5.5e-15 55.2 0.0 9.7e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cys_Met_Meta_PP PF01053.15 KKK24558.1 - 1e-141 471.7 0.1 1.1e-141 471.5 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KKK24558.1 - 2.5e-08 33.2 0.2 4.8e-08 32.3 0.2 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KKK24558.1 - 9.6e-08 31.4 0.4 1.6e-07 30.7 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KKK24558.1 - 1.1e-07 30.9 0.5 2e-07 30.0 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KKK24558.1 - 5.5e-05 22.4 0.1 0.00013 21.2 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Methyltransf_16 PF10294.4 KKK24559.1 - 4.1e-06 26.3 0.0 0.00036 20.0 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Ribosomal_60s PF00428.14 KKK24559.1 - 0.0075 16.6 0.9 0.0075 16.6 0.6 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Myc_N PF01056.13 KKK24559.1 - 0.029 13.5 0.6 0.044 12.9 0.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.11 KKK24559.1 - 0.034 13.1 0.2 0.055 12.4 0.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Methyltransf_31 PF13847.1 KKK24559.1 - 0.068 12.7 0.0 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 KKK24559.1 - 0.14 12.5 0.0 5.1 7.5 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.1 KKK24561.1 - 1e-29 104.1 0.0 1.6e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK24561.1 - 2.1e-08 34.3 0.0 2.1e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK24561.1 - 1.1e-05 25.3 0.3 0.0016 18.2 0.3 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KKK24561.1 - 2.3e-05 23.4 0.0 0.00041 19.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GPI-anchored PF10342.4 KKK24562.1 - 3e-20 72.5 4.3 3e-20 72.5 3.0 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIA PF03153.8 KKK24562.1 - 0.33 10.7 3.1 0.34 10.7 2.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.5 KKK24562.1 - 1.4 8.4 11.7 1.7 8.2 8.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.4 KKK24562.1 - 4.8 5.3 13.0 5.4 5.1 9.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Filament PF00038.16 KKK24564.1 - 1.5 8.1 64.2 1.5 8.1 42.0 2.4 1 1 0 1 1 1 0 Intermediate filament protein STT3 PF02516.9 KKK24565.1 - 1.4e-131 439.7 37.9 1.4e-126 423.2 25.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.7 KKK24566.1 - 6.7e-21 74.0 0.4 7e-21 73.9 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain UCR_14kD PF02271.11 KKK24566.1 - 0.063 13.0 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit PCI_Csn8 PF10075.4 KKK24567.1 - 1.3e-34 119.0 0.0 1.6e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KKK24567.1 - 0.00027 20.5 0.1 0.00035 20.1 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Coiled-coil_56 PF09813.4 KKK24568.1 - 5e-05 23.2 0.0 5.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 APH PF01636.18 KKK24569.1 - 2.6e-14 53.5 0.0 1.2e-13 51.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KKK24569.1 - 0.00032 19.4 0.1 0.13 10.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) DUF3453 PF11935.3 KKK24570.1 - 6.6e-75 251.5 0.0 1.2e-74 250.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) MFS_1 PF07690.11 KKK24571.1 - 7.5e-31 107.1 30.2 9.3e-31 106.8 20.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK24571.1 - 1.2e-09 37.3 16.9 1.9e-09 36.6 7.5 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter Lin-8 PF03353.10 KKK24572.1 - 3.4 6.8 6.5 12 5.0 4.5 1.8 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist RRM_1 PF00076.17 KKK24573.1 - 1.8e-09 37.0 0.0 4.5e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK24573.1 - 1.1e-08 34.7 0.0 0.0026 17.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK24573.1 - 8.7e-07 28.8 0.0 0.00044 20.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) dNK PF01712.14 KKK24573.1 - 0.025 14.4 7.1 0.058 13.3 4.9 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase Ycf1 PF05758.7 KKK24573.1 - 1.3 6.6 8.4 1.9 6.1 5.8 1.3 1 0 0 1 1 1 0 Ycf1 BTV_NS2 PF04514.7 KKK24573.1 - 3.3 6.4 14.1 7.2 5.3 9.7 1.6 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 WD40 PF00400.27 KKK24574.1 - 3.1e-18 64.8 4.4 3e-05 23.7 0.0 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat Sds3 PF08598.6 KKK24575.1 - 1.9e-24 86.3 2.1 1.9e-24 86.3 1.5 2.6 2 2 0 2 2 2 1 Sds3-like VIT_2 PF13757.1 KKK24575.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain DUF1487 PF07368.6 KKK24575.1 - 0.076 12.2 0.4 1.5 7.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) Orthopox_F7 PF05813.7 KKK24575.1 - 0.17 11.8 0.1 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Orthopoxvirus F7 protein zf-C2H2 PF00096.21 KKK24576.1 - 2.7e-05 24.2 22.7 0.15 12.5 0.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK24576.1 - 0.83 10.1 23.9 3.6 8.1 0.3 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger DUF2890 PF11081.3 KKK24576.1 - 2 8.4 10.7 0.04 13.9 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) PRKCSH PF07915.8 KKK24577.1 - 2.9e-21 76.0 0.2 9.9e-21 74.3 0.2 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KKK24577.1 - 0.0093 15.4 0.2 0.13 11.7 0.2 2.2 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein SHD1 PF03983.7 KKK24578.1 - 3.9e-36 122.5 0.1 7.1e-36 121.6 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 KKK24578.1 - 2.8e-34 116.2 6.2 9.3e-12 44.1 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 KKK24578.1 - 3.4e-30 103.3 7.9 1.3e-12 47.1 0.1 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KKK24578.1 - 2.4e-22 78.1 0.3 3.2e-09 36.1 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.6 KKK24578.1 - 0.00083 19.3 26.4 0.00083 19.3 18.3 5.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1720) SH3_3 PF08239.6 KKK24578.1 - 0.0011 19.0 5.6 0.26 11.5 0.6 2.7 3 0 0 3 3 3 2 Bacterial SH3 domain PMT PF02366.13 KKK24579.1 - 3.1e-82 275.6 19.2 5.3e-82 274.8 13.3 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KKK24579.1 - 1.9e-19 69.9 0.6 3.2e-19 69.2 0.4 1.3 1 0 0 1 1 1 1 MIR domain Pirin PF02678.11 KKK24580.1 - 1.3e-30 105.4 0.1 3e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 KKK24580.1 - 1.7e-23 82.6 0.0 7.5e-23 80.5 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KKK24580.1 - 4.4e-05 22.9 2.1 0.0001 21.7 0.8 2.1 2 0 0 2 2 2 1 Cupin domain CDC50 PF03381.10 KKK24587.1 - 4.3e-100 334.4 0.0 5.4e-100 334.1 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 KKK24587.1 - 0.17 12.0 1.7 3.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) SWIRM PF04433.12 KKK24588.1 - 1.2e-14 54.1 0.0 2.1e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain SPT16 PF08644.6 KKK24589.1 - 6.6e-60 201.3 0.0 1.6e-59 200.1 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KKK24589.1 - 2.4e-52 176.7 0.0 1e-51 174.7 0.0 2.2 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KKK24589.1 - 6.4e-23 81.4 0.0 1.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KKK24589.1 - 3e-19 68.7 0.0 9.2e-19 67.2 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.1 KKK24589.1 - 0.14 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Peptidase_M43 PF05572.8 KKK24590.1 - 4.2e-13 49.1 0.0 9.8e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 KKK24590.1 - 0.0001 21.9 0.8 0.00025 20.6 0.6 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KKK24590.1 - 0.0015 18.4 4.0 0.0054 16.6 2.8 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KKK24590.1 - 0.011 16.2 0.2 0.024 15.1 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KKK24590.1 - 0.012 15.7 2.5 0.023 14.7 1.6 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF382 PF04037.8 KKK24591.1 - 1.4e-60 202.7 0.8 2.7e-60 201.8 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 KKK24591.1 - 1.4e-20 72.4 9.8 3.8e-20 71.0 6.8 1.8 1 0 0 1 1 1 1 PSP Sugar_tr PF00083.19 KKK24592.1 - 1.4e-100 337.0 12.1 1.8e-100 336.6 8.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24592.1 - 9.8e-32 110.0 25.0 1.7e-31 109.2 12.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.22 KKK24592.1 - 1.7e-19 69.3 0.0 2.4e-13 49.6 0.0 3.1 2 0 0 2 2 2 2 Mitochondrial carrier protein MFS_1_like PF12832.2 KKK24592.1 - 0.0094 15.7 0.4 0.035 13.8 0.1 2.1 2 0 0 2 2 2 1 MFS_1 like family PMT PF02366.13 KKK24593.1 - 5.2e-83 278.1 17.9 5.2e-83 278.1 12.4 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KKK24593.1 - 2.1e-39 135.0 0.3 2.9e-39 134.5 0.2 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 KKK24594.1 - 6.7e-48 162.1 0.0 6.1e-37 126.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KKK24594.1 - 9e-16 58.4 0.0 2.3e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 KKK24594.1 - 2.9e-11 42.8 0.0 1.7e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK24594.1 - 7.7e-10 38.5 0.0 5.1e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KKK24594.1 - 2.2e-06 27.0 0.0 6.1e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK24594.1 - 0.00026 20.9 0.0 0.0016 18.4 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KKK24594.1 - 0.022 14.9 0.1 0.14 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KKK24594.1 - 0.054 12.8 0.0 10 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KKK24594.1 - 0.063 12.4 0.1 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Flu_M1_C PF08289.6 KKK24594.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Choline_transpo PF04515.7 KKK24595.1 - 3.2e-08 32.7 16.8 3.2e-08 32.7 11.6 3.0 3 0 0 3 3 3 2 Plasma-membrane choline transporter LSM PF01423.17 KKK24599.1 - 4.5e-16 58.1 0.1 6.9e-16 57.5 0.1 1.3 1 0 0 1 1 1 1 LSM domain WH2 PF02205.15 KKK24600.1 - 1.7e-08 33.8 0.2 5.2e-08 32.2 0.2 1.8 1 0 0 1 1 1 1 WH2 motif Ribosomal_L1 PF00687.16 KKK24602.1 - 2.1e-53 180.9 0.5 2.6e-53 180.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.13 KKK24602.1 - 0.022 13.2 0.1 0.03 12.8 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Fungal_trans PF04082.13 KKK24603.1 - 5e-21 74.7 1.7 8.6e-21 73.9 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.13 KKK24604.1 - 1.4e-06 27.5 2.6 0.0029 16.6 0.6 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein VIT1 PF01988.14 KKK24604.1 - 0.036 13.5 1.8 0.058 12.8 1.3 1.3 1 0 0 1 1 1 0 VIT family Arf PF00025.16 KKK24605.1 - 7.4e-80 266.2 0.1 8.7e-80 266.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KKK24605.1 - 4.3e-15 55.3 0.0 5.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KKK24605.1 - 3.7e-13 49.1 0.0 4.1e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KKK24605.1 - 1.9e-12 46.5 1.6 2.2e-09 36.5 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KKK24605.1 - 6.7e-11 41.7 0.0 8.1e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK24605.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK24605.1 - 2.8e-06 27.2 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK24605.1 - 0.0087 15.5 0.1 0.074 12.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 KKK24605.1 - 0.011 14.8 0.4 0.018 14.0 0.3 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 KKK24605.1 - 0.065 13.1 0.1 0.12 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF3405 PF11885.3 KKK24607.1 - 3e-223 741.5 0.3 3.5e-223 741.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Sod_Cu PF00080.15 KKK24608.1 - 7.5e-15 55.3 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) bZIP_1 PF00170.16 KKK24610.1 - 1.9e-08 34.0 14.3 3.4e-08 33.3 9.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK24610.1 - 0.0017 18.1 16.3 0.0022 17.7 10.4 1.8 1 1 1 2 2 2 1 Basic region leucine zipper HOOK PF05622.7 KKK24610.1 - 0.01 13.7 1.4 0.014 13.2 1.0 1.1 1 0 0 1 1 1 0 HOOK protein TMF_TATA_bd PF12325.3 KKK24610.1 - 0.012 15.3 3.9 0.021 14.5 2.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CCDC155 PF14662.1 KKK24610.1 - 0.022 14.3 7.2 0.033 13.7 5.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF724 PF05266.9 KKK24610.1 - 0.067 12.8 5.6 0.13 11.9 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) bZIP_Maf PF03131.12 KKK24610.1 - 0.069 13.4 9.8 0.12 12.6 6.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Phage_lysis PF03245.8 KKK24610.1 - 0.68 9.9 7.9 0.33 10.9 3.2 1.9 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein DUF444 PF04285.7 KKK24610.1 - 1 7.9 4.4 1.4 7.4 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Adeno_PIX PF03955.9 KKK24610.1 - 1.1 9.7 3.8 9.9 6.7 1.8 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Pkinase PF00069.20 KKK24611.1 - 2.9e-38 131.5 0.0 3.8e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24611.1 - 1.1e-13 50.9 0.0 1.6e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK24611.1 - 2.6e-05 24.1 0.0 0.0016 18.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family ACT_7 PF13840.1 KKK24612.1 - 5.5e-23 80.2 0.3 2.8e-15 55.6 0.0 3.5 3 0 0 3 3 3 3 ACT domain GHMP_kinases_N PF00288.21 KKK24614.1 - 3e-11 43.2 0.4 8.8e-11 41.7 0.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain zf-C2H2_4 PF13894.1 KKK24615.1 - 0.00014 21.9 24.4 0.22 11.9 0.4 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK24615.1 - 0.0032 17.6 25.5 0.032 14.5 1.2 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK24615.1 - 0.027 14.5 3.6 0.027 14.5 2.5 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 KKK24615.1 - 0.21 11.4 3.6 4 7.3 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_2 PF12756.2 KKK24615.1 - 0.63 10.1 12.7 0.66 10.1 2.5 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Ndc1_Nup PF09531.5 KKK24616.1 - 2.1e-156 521.8 0.0 2.4e-156 521.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 KKK24617.1 - 4.8e-25 87.5 3.3 4.8e-25 87.5 2.3 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KKK24617.1 - 1.6e-17 62.8 1.8 1.6e-17 62.8 1.2 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KKK24617.1 - 0.0013 18.8 0.4 0.0013 18.8 0.3 2.9 1 1 1 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 KKK24617.1 - 0.014 14.9 0.1 0.061 12.9 0.1 2.1 1 0 0 1 1 1 0 Synaptobrevin Toxin_61 PF15538.1 KKK24617.1 - 0.064 13.2 0.8 0.2 11.6 0.7 1.7 2 0 0 2 2 2 0 Putative toxin 61 OmpH PF03938.9 KKK24617.1 - 0.44 10.4 15.1 0.67 9.8 10.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF883 PF05957.8 KKK24617.1 - 0.68 10.3 0.1 0.68 10.3 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 KKK24617.1 - 0.76 9.5 4.4 5.2 6.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2951 PF11166.3 KKK24617.1 - 1.7 8.5 6.1 1.4 8.7 0.1 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2951) Cyto_heme_lyase PF01265.12 KKK24618.1 - 4.2e-79 265.7 0.1 5.2e-78 262.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Rav1p_C PF12234.3 KKK24633.1 - 2.5e-276 917.9 0.0 3.1e-276 917.6 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KKK24633.1 - 3.6e-05 23.4 0.5 1.1 9.2 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat 2-Hacid_dh_C PF02826.14 KKK24635.1 - 1.2e-32 112.4 0.0 1.9e-26 92.2 0.0 2.2 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK24635.1 - 1.1e-17 63.6 0.0 1.4e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain OPT PF03169.10 KKK24636.1 - 7.2e-180 599.4 17.7 8.3e-180 599.2 12.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 KKK24636.1 - 0.67 9.9 9.7 4 7.5 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) SH3_9 PF14604.1 KKK24637.1 - 1.7e-10 40.3 0.0 2.7e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK24637.1 - 1.8e-07 30.4 0.0 3.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK24637.1 - 4e-07 29.4 0.0 9.1e-07 28.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M56 PF05569.6 KKK24637.1 - 0.037 13.0 0.3 0.059 12.3 0.1 1.4 1 1 0 1 1 1 0 BlaR1 peptidase M56 Macoilin PF09726.4 KKK24637.1 - 0.039 12.2 4.4 0.043 12.1 3.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3619 PF12279.3 KKK24637.1 - 0.07 13.2 0.2 0.19 11.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) MtrF PF09472.5 KKK24637.1 - 0.075 12.2 2.4 0.15 11.3 1.7 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3042 PF11240.3 KKK24637.1 - 0.12 12.1 3.9 0.64 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Rifin_STEVOR PF02009.11 KKK24637.1 - 0.77 9.3 9.4 2.5 7.6 6.6 1.7 1 1 0 1 1 1 0 Rifin/stevor family DUF4448 PF14610.1 KKK24637.1 - 0.91 8.9 7.3 0.072 12.5 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) SKG6 PF08693.5 KKK24637.1 - 1.2 8.4 5.1 0.28 10.5 0.1 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Pkinase PF00069.20 KKK24638.1 - 9.3e-44 149.5 0.0 1.4e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24638.1 - 4.7e-16 58.6 0.0 6.9e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK24638.1 - 0.0005 19.8 0.2 0.36 10.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family KIX PF02172.11 KKK24638.1 - 0.00072 19.5 0.4 0.0014 18.6 0.2 1.4 1 0 0 1 1 1 1 KIX domain Kdo PF06293.9 KKK24638.1 - 0.016 14.3 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KKK24638.1 - 0.028 13.3 0.1 0.066 12.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.4 KKK24638.1 - 0.062 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WPP PF13943.1 KKK24638.1 - 0.15 12.3 3.0 0.43 10.8 1.1 2.3 2 0 0 2 2 2 0 WPP domain muHD PF10291.4 KKK24639.1 - 2.5e-88 295.5 0.3 3.6e-88 295.0 0.2 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KKK24639.1 - 8.3e-12 45.1 0.6 3.5e-11 43.1 0.0 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Sfi1 PF08457.5 KKK24640.1 - 3.6e-208 692.6 82.2 3.6e-208 692.6 57.0 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Cmc1 PF08583.5 KKK24641.1 - 0.0078 15.9 1.9 0.0078 15.9 1.3 1.6 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 KKK24641.1 - 0.014 14.8 1.0 1.9 7.9 0.1 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 KKK24641.1 - 0.03 14.2 1.9 0.083 12.8 1.3 1.7 1 1 0 1 1 1 0 CHCH domain EPSP_synthase PF00275.15 KKK24642.1 - 7e-126 420.0 0.0 1.1e-125 419.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KKK24642.1 - 2.9e-97 324.6 0.1 7.1e-97 323.4 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KKK24642.1 - 5.9e-63 212.5 0.0 1e-62 211.7 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KKK24642.1 - 1.9e-39 135.0 0.0 1.6e-38 132.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KKK24642.1 - 3.6e-24 84.6 0.0 8.9e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KKK24642.1 - 2.9e-11 43.6 0.0 7.6e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KKK24642.1 - 3.7e-08 32.9 0.0 8.7e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KKK24642.1 - 2e-05 25.3 0.0 0.00026 21.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KKK24642.1 - 0.016 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KKK24642.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Myotub-related PF06602.9 KKK24642.1 - 0.22 10.2 0.0 0.5 9.0 0.0 1.5 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain tRNA-synt_1 PF00133.17 KKK24643.1 - 1.9e-151 505.0 0.0 3.2e-151 504.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KKK24643.1 - 1.1e-27 96.6 0.1 3.2e-27 95.1 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KKK24643.1 - 3.8e-07 29.0 0.0 0.0028 16.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KKK24644.1 - 1.3e-50 172.0 0.0 1.5e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KKK24644.1 - 4.1e-07 29.0 0.0 5e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) Uso1_p115_head PF04869.9 KKK24645.1 - 4.2e-112 373.9 0.0 8.4e-112 372.9 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KKK24645.1 - 2.5e-08 33.9 28.2 2.5e-08 33.9 19.5 3.8 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.16 KKK24645.1 - 2.8e-05 23.7 50.1 0.00086 18.8 9.7 2.4 1 1 1 2 2 2 2 Intermediate filament protein IncA PF04156.9 KKK24645.1 - 0.0017 17.9 19.0 0.0017 17.9 13.2 4.5 1 1 2 3 3 3 1 IncA protein Arm PF00514.18 KKK24645.1 - 0.01 15.6 0.8 3.4 7.6 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF3584 PF12128.3 KKK24645.1 - 0.56 7.4 55.7 0.38 8.0 16.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 KKK24645.1 - 2.4 7.2 15.7 0.39 9.8 4.8 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KKK24645.1 - 2.8 7.7 16.4 3.3 7.5 2.7 4.4 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus XRN_N PF03159.13 KKK24646.1 - 3.4e-108 360.4 0.6 3e-106 354.1 0.0 2.2 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 KKK24646.1 - 0.078 12.9 2.8 0.14 12.1 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 KKK24646.1 - 0.12 12.0 0.7 0.24 11.0 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Fungal_trans PF04082.13 KKK24656.1 - 2.4e-13 49.5 1.8 4.6e-13 48.6 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK24656.1 - 8.3e-07 29.0 5.1 9.9e-05 22.4 0.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK24656.1 - 1.3e-06 28.3 1.5 1.3e-06 28.3 1.0 2.7 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.13 KKK24656.1 - 7.6e-06 25.7 12.6 7.6e-06 25.7 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KKK24656.1 - 4.4e-05 23.5 4.2 0.0054 16.9 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KKK24656.1 - 0.00016 21.7 1.4 0.041 14.0 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK24656.1 - 0.0047 17.0 0.8 0.067 13.3 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding HTH_OrfB_IS605 PF12323.3 KKK24656.1 - 0.46 9.8 2.1 14 5.1 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain LigB PF02900.13 KKK24657.1 - 4.2e-19 68.5 0.3 1.2e-17 63.7 0.2 2.0 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Nsp3_PL2pro PF12124.3 KKK24657.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Aldedh PF00171.17 KKK24658.1 - 6.9e-11 41.1 0.3 3.5e-06 25.6 0.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family MitoNEET_N PF10660.4 KKK24658.1 - 0.064 13.1 0.4 0.16 11.8 0.3 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Peptidase_S15 PF02129.13 KKK24660.1 - 1.2e-39 136.3 0.5 1.7e-39 135.9 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KKK24660.1 - 1.4e-38 132.9 0.3 2.4e-38 132.2 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KKK24660.1 - 1.3e-05 25.2 0.3 2.2e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK24660.1 - 3.3e-05 23.6 0.0 8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK24660.1 - 0.0035 17.1 0.0 0.0091 15.8 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Methyltransf_23 PF13489.1 KKK24661.1 - 1.5e-22 80.0 0.0 2.1e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK24661.1 - 9.6e-14 51.6 0.0 2.2e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK24661.1 - 9.9e-12 44.6 0.0 7.2e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK24661.1 - 6.6e-10 39.5 0.0 1.4e-08 35.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK24661.1 - 4.2e-09 36.7 0.0 3.3e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK24661.1 - 2.8e-07 29.8 0.0 0.0028 16.8 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KKK24661.1 - 3.7e-05 23.7 0.0 0.00022 21.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KKK24661.1 - 7.8e-05 21.8 0.0 0.00014 21.0 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KKK24661.1 - 0.00037 19.9 0.0 0.005 16.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KKK24661.1 - 0.00061 20.1 0.0 0.0038 17.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KKK24661.1 - 0.0027 16.8 0.0 0.015 14.3 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KKK24661.1 - 0.011 15.7 0.0 0.04 13.8 0.0 1.8 1 1 1 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 KKK24661.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 KKK24661.1 - 0.026 13.7 0.0 0.089 11.9 0.0 1.9 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_16 PF10294.4 KKK24661.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FAD_binding_3 PF01494.14 KKK24662.1 - 3.9e-26 91.9 1.3 1.2e-16 60.7 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 KKK24662.1 - 0.00011 21.1 0.4 0.0002 20.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KKK24662.1 - 0.00021 20.3 0.2 0.00092 18.2 0.1 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KKK24662.1 - 0.0017 18.3 0.1 0.0044 17.0 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 KKK24662.1 - 0.0018 17.2 0.8 0.0057 15.6 0.0 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 KKK24662.1 - 0.0056 17.0 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK24662.1 - 0.0058 16.7 0.4 0.032 14.2 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK24662.1 - 0.0075 16.2 0.1 0.031 14.3 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PALP PF00291.20 KKK24662.1 - 0.019 14.1 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Thi4 PF01946.12 KKK24662.1 - 0.026 13.6 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KKK24662.1 - 0.052 13.4 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KKK24662.1 - 0.066 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 KKK24662.1 - 0.084 12.2 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain CPSase_L_chain PF00289.17 KKK24662.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Pho88 PF10032.4 KKK24663.1 - 1.6e-78 262.3 0.1 2e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Histone PF00125.19 KKK24664.1 - 4.2e-22 78.0 0.0 5.5e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KKK24664.1 - 4.8e-05 23.3 0.0 6.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Gp_dh_C PF02800.15 KKK24665.1 - 4.3e-76 253.6 0.1 6.5e-76 253.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KKK24665.1 - 5.3e-56 188.7 0.0 9.5e-56 187.9 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2436 PF10365.4 KKK24665.1 - 0.054 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) ADH_zinc_N PF00107.21 KKK24665.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DotA PF11388.3 KKK24666.1 - 0.043 13.8 0.0 0.059 13.4 0.0 1.3 1 1 0 1 1 1 0 Phagosome trafficking protein DotA Apq12 PF12716.2 KKK24674.1 - 2.9e-18 65.2 12.7 4.9e-18 64.5 8.8 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis vMSA PF00695.14 KKK24674.1 - 0.019 14.1 0.2 0.027 13.6 0.2 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF412 PF04217.8 KKK24674.1 - 0.068 12.9 3.0 0.12 12.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF412 RNase_H PF00075.19 KKK24675.1 - 5.2e-20 72.1 0.0 6.8e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KKK24675.1 - 0.0018 18.0 0.1 0.037 13.8 0.0 2.3 2 1 0 2 2 2 1 Reverse transcriptase-like S-AdoMet_synt_C PF02773.11 KKK24676.1 - 5.5e-77 256.1 1.2 2.6e-76 253.9 0.2 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KKK24676.1 - 1.3e-47 160.7 0.0 2.2e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KKK24676.1 - 1.2e-42 144.2 0.6 2.3e-42 143.2 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Lactamase_B_3 PF13483.1 KKK24676.1 - 0.075 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain ATP_bind_1 PF03029.12 KKK24677.1 - 4.8e-76 255.4 0.1 6.4e-76 255.0 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KKK24677.1 - 0.00016 22.5 0.0 0.00044 21.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK24677.1 - 0.00035 20.4 0.0 0.00071 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KKK24677.1 - 0.00059 19.4 0.1 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KKK24677.1 - 0.0007 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KKK24677.1 - 0.0011 19.1 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KKK24677.1 - 0.0021 17.7 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KKK24677.1 - 0.0024 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KKK24677.1 - 0.003 17.6 0.0 0.0077 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 KKK24677.1 - 0.0042 17.0 0.3 0.059 13.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 KKK24677.1 - 0.0054 16.2 0.1 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KKK24677.1 - 0.0069 15.3 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 KKK24677.1 - 0.0071 16.5 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KKK24677.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain NACHT PF05729.7 KKK24677.1 - 0.008 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KKK24677.1 - 0.014 15.6 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_31 PF13614.1 KKK24677.1 - 0.026 14.4 0.1 0.28 11.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KKK24677.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KKK24677.1 - 0.035 13.5 0.0 0.86 9.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 KKK24677.1 - 0.039 12.9 0.0 0.067 12.1 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Septin PF00735.13 KKK24677.1 - 0.045 12.7 0.1 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 KKK24677.1 - 0.048 13.3 0.0 0.15 11.7 0.0 1.9 2 1 0 2 2 2 0 Archaeal ATPase SRP54 PF00448.17 KKK24677.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 KKK24677.1 - 0.055 12.9 0.1 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KKK24677.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KKK24677.1 - 0.073 12.6 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 KKK24677.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase GTP_EFTU PF00009.22 KKK24677.1 - 0.087 12.2 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain KaiC PF06745.8 KKK24677.1 - 0.095 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiC Gtr1_RagA PF04670.7 KKK24677.1 - 0.1 11.7 0.0 0.41 9.7 0.0 2.0 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK24677.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase SLD3 PF08639.5 KKK24678.1 - 4.7e-146 487.3 2.7 6.6e-146 486.8 1.8 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 Cytochrom_C552 PF02335.10 KKK24679.1 - 5.8 5.5 9.1 0.95 8.0 3.4 1.8 2 1 0 2 2 2 0 Cytochrome c552 bZIP_1 PF00170.16 KKK24699.1 - 0.00056 19.8 10.2 0.0021 17.9 7.1 1.9 1 1 0 1 1 1 1 bZIP transcription factor UDG PF03167.14 KKK24699.1 - 0.081 12.3 0.3 0.081 12.3 0.2 1.7 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily bZIP_2 PF07716.10 KKK24699.1 - 0.081 12.7 13.4 0.26 11.1 5.1 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Zip PF02535.17 KKK24699.1 - 0.89 8.4 4.4 1.2 8.0 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SPRY PF00622.23 KKK24700.1 - 1.1e-20 74.0 0.2 2.3e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 SPRY domain Amidase PF01425.16 KKK24701.1 - 3.7e-07 29.3 0.0 4.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Amidase PDEase_II PF02112.10 KKK24702.1 - 7.2e-54 182.9 0.0 2.4e-45 154.9 0.0 2.7 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KKK24702.1 - 0.00092 18.8 0.1 0.0042 16.6 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KKK24702.1 - 0.0046 16.6 0.1 0.0084 15.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily GWT1 PF06423.7 KKK24703.1 - 3.8e-38 130.6 3.1 1e-37 129.2 2.2 1.8 1 0 0 1 1 1 1 GWT1 Amidase PF01425.16 KKK24704.1 - 1.3e-73 248.3 0.3 1.9e-73 247.8 0.2 1.1 1 0 0 1 1 1 1 Amidase Pkinase PF00069.20 KKK24705.1 - 2.2e-58 197.4 0.0 3e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24705.1 - 1e-24 87.0 0.0 1.5e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK24705.1 - 1.5e-07 30.6 0.0 2.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK24705.1 - 0.012 14.6 0.0 0.035 13.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK24705.1 - 0.027 14.1 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family UQ_con PF00179.21 KKK24706.1 - 6.8e-50 168.1 0.0 8.4e-50 167.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK24706.1 - 6e-05 22.8 0.1 0.00011 21.9 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KKK24706.1 - 0.0004 20.2 0.1 0.0006 19.6 0.1 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KKK24706.1 - 0.0018 17.9 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain A_deaminase PF00962.17 KKK24707.1 - 2.3e-13 49.7 0.0 4.8e-06 25.7 0.0 2.2 1 1 1 2 2 2 2 Adenosine/AMP deaminase PolyA_pol_arg_C PF12626.2 KKK24707.1 - 0.074 12.6 0.4 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus Nucleos_tra2_C PF07662.8 KKK24708.1 - 2e-69 233.2 0.4 2e-69 233.2 0.2 2.5 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KKK24708.1 - 3.9e-23 81.5 4.7 3.9e-23 81.5 3.3 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KKK24708.1 - 7.1 6.5 27.8 0.017 15.0 6.3 3.9 4 1 0 4 4 4 0 Nucleoside recognition ATG2_CAD PF13329.1 KKK24709.1 - 7.9e-41 139.2 0.5 1.9e-40 138.0 0.1 1.9 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KKK24709.1 - 5.9e-26 90.4 0.1 5.4e-25 87.4 0.0 2.4 2 0 0 2 2 2 1 ATG C terminal domain F-box-like PF12937.2 KKK24710.1 - 2.2e-08 33.7 0.1 4.1e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK24710.1 - 1e-06 28.2 0.0 2.4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 KKK24711.1 - 1.1e-27 94.8 1.0 5.9e-06 25.9 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_N PF14781.1 KKK24711.1 - 0.12 12.0 0.1 39 3.8 0.0 3.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal PXA PF02194.10 KKK24713.1 - 3e-53 180.1 0.2 3e-53 180.1 0.1 2.5 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 KKK24713.1 - 2.5e-28 98.4 0.3 1.1e-27 96.3 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KKK24713.1 - 8e-22 77.1 0.6 2e-21 75.8 0.4 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KKK24713.1 - 7.7e-12 45.3 0.1 1.9e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Mucin PF01456.12 KKK24713.1 - 1.1 9.0 24.9 2.6 7.7 17.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein adh_short PF00106.20 KKK24725.1 - 1.6e-05 24.8 0.0 2.8e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase F-box-like PF12937.2 KKK24726.1 - 0.00018 21.1 0.1 0.00018 21.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK24726.1 - 0.00018 21.0 0.0 0.0005 19.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 KKK24726.1 - 0.013 15.4 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 0 PRANC domain Band_7 PF01145.20 KKK24727.1 - 2.5e-27 95.9 3.0 4.9e-27 94.9 2.1 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family EIF_2_alpha PF07541.7 KKK24728.1 - 1.9e-39 133.9 0.0 4.9e-39 132.5 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KKK24728.1 - 2.1e-12 46.9 0.5 4.4e-12 45.9 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain PKD_channel PF08016.7 KKK24729.1 - 1e-05 24.1 22.5 0.0001 20.9 15.0 2.3 1 1 0 1 1 1 1 Polycystin cation channel MADF_DNA_bdg PF10545.4 KKK24729.1 - 0.17 12.0 0.7 0.58 10.3 0.5 1.9 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CENP-L PF13092.1 KKK24730.1 - 1.5e-48 164.6 0.0 2.4e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Sulfate_tra_GLY PF13792.1 KKK24731.1 - 2.1e-27 94.6 4.5 2.1e-27 94.6 3.1 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif Sulfate_transp PF00916.15 KKK24731.1 - 6.1e-26 91.0 11.2 3.1e-21 75.6 0.1 2.8 2 1 1 3 3 3 2 Sulfate transporter family STAS PF01740.16 KKK24731.1 - 6.5e-16 57.8 0.0 1.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KKK24731.1 - 4.9e-05 23.2 0.0 0.00021 21.2 0.0 2.1 2 1 0 2 2 2 1 STAS domain Gram_pos_anchor PF00746.16 KKK24731.1 - 0.55 10.1 5.4 0.47 10.3 0.7 3.0 2 0 0 2 2 2 0 Gram positive anchor Ribosomal_L6e PF01159.14 KKK24732.1 - 3.1e-37 127.1 0.3 5e-37 126.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e DUF1070 PF06376.7 KKK24732.1 - 0.11 12.3 0.6 0.26 11.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1070) Proteasom_Rpn13 PF04683.8 KKK24733.1 - 1.3e-27 95.6 0.0 2e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor SNF2_N PF00176.18 KKK24744.1 - 1.3e-68 230.9 0.1 2e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KKK24744.1 - 1.7e-26 91.6 1.8 2.3e-15 56.0 0.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 KKK24744.1 - 1.3e-14 54.1 0.1 4.5e-14 52.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 KKK24744.1 - 8.8e-13 47.9 0.0 4.4e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 KKK24745.1 - 1.5e-35 122.4 0.0 1.8e-16 60.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KKK24745.1 - 9.3e-14 52.0 5.0 0.014 15.3 0.0 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 KKK24745.1 - 3e-10 39.7 2.4 0.0013 18.0 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KKK24745.1 - 3.7e-07 29.5 0.7 2.9 6.8 0.0 4.7 5 1 1 6 6 5 3 AAA ATPase domain RLI PF04068.10 KKK24745.1 - 6.3e-07 28.8 1.6 6.3e-07 28.8 1.1 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_17 PF13207.1 KKK24745.1 - 4.8e-06 27.4 0.7 0.14 12.9 0.0 3.5 3 2 0 3 3 2 2 AAA domain AAA PF00004.24 KKK24745.1 - 2.6e-05 24.4 0.0 0.026 14.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK24745.1 - 4.3e-05 23.6 0.0 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 KKK24745.1 - 8e-05 22.0 2.5 8e-05 22.0 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 KKK24745.1 - 0.00013 21.4 0.3 0.08 12.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KKK24745.1 - 0.00013 21.1 0.0 0.38 9.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KKK24745.1 - 0.00017 21.9 0.0 0.45 10.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain Fer4_21 PF14697.1 KKK24745.1 - 0.00088 19.0 8.3 0.002 17.9 5.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.1 KKK24745.1 - 0.001 18.9 0.0 0.087 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KKK24745.1 - 0.0012 19.3 0.0 0.087 13.3 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein VirE PF05272.6 KKK24745.1 - 0.0013 18.1 0.1 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E RNA_helicase PF00910.17 KKK24745.1 - 0.0031 17.6 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase MobB PF03205.9 KKK24745.1 - 0.0032 17.1 0.8 0.49 10.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KKK24745.1 - 0.0037 16.7 0.1 2.2 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KKK24745.1 - 0.004 16.7 0.2 0.059 13.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 KKK24745.1 - 0.0049 15.6 0.0 0.072 11.7 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 KKK24745.1 - 0.0083 15.5 2.7 0.17 11.3 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.2 KKK24745.1 - 0.01 15.6 2.1 0.01 15.6 1.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_23 PF13476.1 KKK24745.1 - 0.013 15.8 2.9 0.26 11.5 0.4 2.7 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 KKK24745.1 - 0.013 15.1 2.5 0.57 9.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Fer4_10 PF13237.1 KKK24745.1 - 0.016 14.9 1.6 0.016 14.9 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 KKK24745.1 - 0.022 15.4 3.3 0.048 14.4 0.1 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_13 PF13166.1 KKK24745.1 - 0.037 12.4 0.0 0.037 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KKK24745.1 - 0.047 13.6 0.0 3.8 7.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KKK24745.1 - 0.052 13.4 0.0 5 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KKK24745.1 - 0.067 12.6 1.9 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_7 PF12838.2 KKK24745.1 - 0.078 13.3 9.2 0.29 11.5 6.4 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain NB-ARC PF00931.17 KKK24745.1 - 0.082 11.7 0.3 11 4.7 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain Thymidylate_kin PF02223.12 KKK24745.1 - 0.11 11.8 0.1 16 4.8 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase KaiC PF06745.8 KKK24745.1 - 0.12 11.4 0.1 0.24 10.4 0.1 1.5 1 0 0 1 1 1 0 KaiC HflK_N PF12221.3 KKK24745.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Fer4_8 PF13183.1 KKK24745.1 - 0.13 12.3 8.0 0.59 10.1 5.8 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain DLIC PF05783.6 KKK24745.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Fer4_17 PF13534.1 KKK24745.1 - 0.19 12.0 0.2 0.19 12.0 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 KKK24745.1 - 0.22 11.0 2.1 1 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 KKK24745.1 - 3.7 7.9 16.1 0.067 13.4 1.5 2.4 2 1 1 3 3 2 0 4Fe-4S dicluster domain PRA1 PF03208.14 KKK24755.1 - 3.2e-42 143.4 1.2 3.8e-42 143.2 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein TraS PF10624.4 KKK24755.1 - 1.7 8.1 4.9 0.69 9.4 0.9 1.9 1 1 1 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS SNF2_N PF00176.18 KKK24756.1 - 5.8e-52 176.3 0.5 2.1e-51 174.5 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 KKK24756.1 - 3.2e-08 33.1 8.6 7.5e-08 31.9 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK24756.1 - 4.9e-08 32.6 10.2 1.5e-07 31.0 7.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK24756.1 - 2.5e-07 30.2 8.0 6.4e-07 28.9 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK24756.1 - 8.4e-06 25.7 10.8 2.2e-05 24.3 7.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK24756.1 - 0.00012 21.7 8.6 0.00029 20.4 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KKK24756.1 - 0.00035 20.6 6.0 0.00035 20.6 2.9 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger Helicase_C PF00271.26 KKK24756.1 - 0.00042 20.1 0.0 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.1 KKK24756.1 - 0.009 15.5 4.1 0.02 14.4 2.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KKK24756.1 - 0.024 14.3 4.9 0.12 12.0 3.5 2.1 1 1 1 2 2 2 0 RING-type zinc-finger YopE PF03545.8 KKK24756.1 - 0.026 14.4 0.5 1.5 8.8 0.0 2.8 2 0 0 2 2 2 0 Yersinia virulence determinant (YopE) zf-C3HC4_4 PF15227.1 KKK24756.1 - 0.041 13.7 7.2 0.1 12.4 5.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DrsE PF02635.10 KKK24756.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 DsrE/DsrF-like family Baculo_IE-1 PF05290.6 KKK24756.1 - 0.14 11.9 2.6 0.18 11.5 0.3 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-P11 PF03854.9 KKK24756.1 - 0.76 9.2 8.1 2 7.9 5.6 1.7 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.2 KKK24756.1 - 3.6 7.4 6.8 4.9 7.0 2.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon PNGaseA PF12222.3 KKK24757.1 - 8.8e-186 617.9 3.0 1.1e-185 617.5 2.1 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1640 PF07798.6 KKK24757.1 - 8e-64 214.9 6.7 1.3e-63 214.2 4.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Metal_resist PF13801.1 KKK24757.1 - 0.34 10.9 2.6 0.78 9.7 1.8 1.6 1 0 0 1 1 1 0 Heavy-metal resistance Fungal_trans_2 PF11951.3 KKK24758.1 - 1.4e-14 53.4 1.8 2.1e-14 52.9 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ecm29 PF13001.2 KKK24759.1 - 8.2e-158 525.9 0.0 1.8e-157 524.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome stabiliser Pec_lyase PF09492.5 KKK24759.1 - 0.27 10.3 0.1 3.3 6.8 0.0 2.4 3 0 0 3 3 3 0 Pectic acid lyase WW PF00397.21 KKK24760.1 - 4.1e-09 36.1 0.6 9.2e-09 35.0 0.4 1.7 1 0 0 1 1 1 1 WW domain Hom_end_hint PF05203.11 KKK24760.1 - 0.0047 16.7 0.0 0.0063 16.2 0.0 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint FAM60A PF15396.1 KKK24760.1 - 6.2 6.5 8.9 11 5.7 6.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A HlyD_2 PF12700.2 KKK24760.1 - 9.3 5.2 13.0 13 4.7 9.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Frag1 PF10277.4 KKK24761.1 - 2e-39 135.2 10.8 2.3e-39 135.0 7.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3671 PF12420.3 KKK24761.1 - 0.33 10.9 9.3 0.076 12.9 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function SUR7 PF06687.7 KKK24761.1 - 5.4 6.5 14.8 2 7.9 5.5 2.6 1 1 1 2 2 2 0 SUR7/PalI family DnaJ PF00226.26 KKK24763.1 - 6.4e-12 45.0 1.8 2.1e-11 43.3 1.2 1.8 1 1 0 1 1 1 1 DnaJ domain Y_phosphatase3 PF13350.1 KKK24764.1 - 1.7e-17 64.1 0.1 7e-12 45.8 0.0 2.5 2 1 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 KKK24764.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KKK24764.1 - 0.0024 17.2 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KKK24764.1 - 0.0075 15.8 0.0 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Enoyl_reductase PF12241.3 KKK24764.1 - 0.081 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Myotub-related PF06602.9 KKK24764.1 - 0.11 11.2 0.1 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PMM PF03332.8 KKK24766.1 - 2.5e-101 337.8 0.2 3.3e-101 337.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DnaJ PF00226.26 KKK24766.1 - 1.3e-17 63.2 0.1 3.1e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain S6PP PF05116.8 KKK24766.1 - 0.0048 16.2 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 KKK24766.1 - 0.0099 15.4 0.0 0.04 13.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 KKK24766.1 - 0.013 14.6 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF456 PF04306.8 KKK24766.1 - 0.027 14.5 0.2 0.04 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 KKK24766.1 - 0.059 13.0 2.4 0.13 11.9 1.6 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 KKK24766.1 - 1 9.4 6.0 2.6 8.2 4.1 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide G-patch PF01585.18 KKK24767.1 - 1e-10 41.2 1.3 2.2e-10 40.1 0.9 1.6 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 KKK24767.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK24767.1 - 0.00016 21.1 0.2 0.00053 19.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KKK24767.1 - 0.011 15.5 0.7 0.035 13.9 0.5 1.8 1 0 0 1 1 1 0 DExH-box splicing factor binding site RRM_6 PF14259.1 KKK24767.1 - 0.17 11.8 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 KKK24768.1 - 1.2e-48 164.1 0.0 1.3e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK24768.1 - 0.00012 21.7 0.0 0.00015 21.4 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KKK24768.1 - 0.05 13.5 0.6 0.069 13.0 0.4 1.5 1 1 0 1 1 1 0 RWD domain AMP-binding PF00501.23 KKK24769.1 - 7.1e-83 278.3 0.0 9.1e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK24769.1 - 3.3e-13 50.3 0.0 1.8e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KKK24769.1 - 0.0019 16.7 0.0 0.009 14.5 0.0 1.8 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Pkinase PF00069.20 KKK24770.1 - 3.5e-07 29.6 0.1 4.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KKK24770.1 - 5.6e-07 28.8 0.0 8.1e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KKK24770.1 - 0.0083 15.2 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DEAD PF00270.24 KKK24771.1 - 7.4e-40 136.2 0.4 1.6e-39 135.0 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK24771.1 - 1.6e-29 101.5 0.2 3.3e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KKK24771.1 - 0.0016 18.1 0.1 0.0039 16.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KKK24771.1 - 0.017 14.9 0.1 0.036 13.8 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KKK24771.1 - 0.023 14.4 0.4 0.094 12.4 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_30 PF13604.1 KKK24771.1 - 0.024 14.2 0.3 0.056 13.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KKK24771.1 - 0.083 13.0 0.7 0.38 10.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KKK24771.1 - 0.14 11.6 0.2 0.19 11.2 0.2 1.5 1 1 0 1 1 1 0 AAA domain Aminotran_5 PF00266.14 KKK24772.1 - 3.7e-20 71.9 0.0 6.9e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 Aminotransferase class-V MOSC_N PF03476.11 KKK24772.1 - 2.1e-10 40.3 0.0 4.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain AAL_decarboxy PF03306.8 KKK24772.1 - 0.035 13.1 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase DNA_ligase_A_M PF01068.16 KKK24773.1 - 7.2e-20 71.2 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KKK24773.1 - 5.6e-11 42.5 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DUF3449 PF11931.3 KKK24774.1 - 1.3e-70 236.9 0.9 3.3e-70 235.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KKK24774.1 - 3.6e-15 55.1 0.6 8.5e-15 53.9 0.4 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 KKK24774.1 - 2.3e-09 37.1 2.4 9.6e-08 31.9 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK24774.1 - 7.8e-08 32.2 0.9 7.8e-08 32.2 0.6 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KKK24774.1 - 0.00085 19.3 0.0 0.0071 16.4 0.0 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Myb_CC_LHEQLE PF14379.1 KKK24774.1 - 0.045 13.3 7.1 23 4.6 4.9 3.1 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif zf-C2H2 PF00096.21 KKK24774.1 - 0.29 11.5 4.0 1.7 9.1 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK24774.1 - 0.34 11.3 2.8 17 6.0 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger WD40 PF00400.27 KKK24776.1 - 3.6e-33 112.2 9.2 4.5e-07 29.5 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KKK24776.1 - 0.072 11.3 0.0 0.95 7.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain ATP-synt_ab PF00006.20 KKK24777.1 - 3.6e-115 382.8 0.0 6.2e-115 382.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KKK24777.1 - 1.8e-16 60.6 0.4 3e-16 59.8 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KKK24777.1 - 2.7e-15 56.3 1.8 5.8e-15 55.2 1.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF1180 PF06679.7 KKK24777.1 - 0.022 14.6 0.7 0.038 13.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Bystin PF05291.6 KKK24779.1 - 5.3e-128 426.1 0.0 7.1e-128 425.7 0.0 1.1 1 0 0 1 1 1 1 Bystin MTP18 PF10558.4 KKK24783.1 - 3.3e-64 215.2 0.0 4.8e-64 214.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Git3 PF11710.3 KKK24787.1 - 3e-38 131.4 17.6 6.2e-38 130.4 12.2 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KKK24787.1 - 2.5e-14 52.7 0.0 9.1e-14 50.9 0.0 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term PDZ_1 PF12812.2 KKK24788.1 - 9.8e-54 179.1 0.0 2.1e-33 114.0 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 KKK24788.1 - 9.8e-15 54.5 0.2 5.4e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 KKK24788.1 - 2.3e-13 49.8 0.0 1.5e-05 24.7 0.0 4.1 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 KKK24788.1 - 3.6e-12 46.3 0.0 3.4e-05 23.9 0.0 3.7 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 KKK24788.1 - 0.00013 21.7 0.3 0.058 13.1 0.1 3.6 3 0 0 3 3 3 1 Tricorn protease PDZ domain Trypsin PF00089.21 KKK24788.1 - 0.0002 21.0 0.0 0.00073 19.1 0.0 1.9 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.16 KKK24788.1 - 0.063 12.6 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 KKK24788.1 - 0.11 11.7 0.2 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 KKK24788.1 - 0.21 9.9 0.4 0.34 9.2 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 Cyclase PF04199.8 KKK24789.1 - 2.1e-11 43.8 0.1 3.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase SSXT PF05030.7 KKK24790.1 - 0.0038 16.7 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 2 SSXT protein (N-terminal region) DUF2486 PF10667.4 KKK24790.1 - 2.7 8.4 10.7 4.4 7.7 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF155 PF02582.9 KKK24791.1 - 1.1e-58 198.0 0.0 1.6e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Acetyltransf_1 PF00583.19 KKK24794.1 - 0.0011 19.0 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KKK24794.1 - 0.0075 16.3 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KKK24794.1 - 0.0088 16.0 0.0 0.03 14.2 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Arf PF00025.16 KKK24795.1 - 8.8e-58 194.3 2.4 2.2e-56 189.8 0.2 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 KKK24795.1 - 3.1e-09 36.4 0.0 3.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KKK24795.1 - 7.9e-08 31.7 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KKK24795.1 - 4e-07 29.0 2.3 5.7e-06 25.2 0.1 2.7 2 1 1 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.18 KKK24795.1 - 8e-07 29.0 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK24795.1 - 1.7e-06 28.5 0.0 2.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KKK24795.1 - 2.4e-06 27.1 0.0 4.3e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KKK24795.1 - 3.7e-05 23.0 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HCV_NS1 PF01560.12 KKK24795.1 - 0.035 12.5 0.0 0.04 12.3 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 AAA_17 PF13207.1 KKK24795.1 - 0.081 13.7 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain HMGL-like PF00682.14 KKK24796.1 - 1.3e-65 221.3 0.0 2.4e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KKK24796.1 - 1.9e-21 76.2 0.0 4.2e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DEAD PF00270.24 KKK24797.1 - 2.6e-44 150.7 1.5 7.6e-44 149.1 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK24797.1 - 1.3e-26 92.1 0.0 6.7e-26 89.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KKK24797.1 - 5.3e-05 21.8 0.0 5.3e-05 21.8 0.0 2.9 2 1 2 4 4 4 1 Protein of unknown function (DUF1253) Zn_clus PF00172.13 KKK24798.1 - 1.9e-08 34.0 14.3 4e-08 33.0 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Multi-haem_cyto PF13447.1 KKK24798.1 - 0.01 14.9 1.5 0.017 14.1 1.0 1.3 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH ALO PF04030.9 KKK24799.1 - 3e-89 299.0 0.3 3.9e-89 298.6 0.2 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KKK24799.1 - 2.2e-34 117.9 0.4 3.2e-34 117.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4045 PF13254.1 KKK24800.1 - 1.1e-148 495.9 29.9 1.1e-148 495.9 20.7 4.9 4 1 0 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 KKK24800.1 - 1.6e-11 43.7 0.0 2.7e-05 23.7 0.0 3.6 3 0 0 3 3 3 3 Gelsolin repeat MIF4G PF02854.14 KKK24801.1 - 1.1e-49 168.6 0.0 1.1e-49 168.6 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 KKK24801.1 - 2.3e-23 81.8 0.4 9.5e-23 79.8 0.3 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Usp PF00582.21 KKK24802.1 - 2.9e-22 79.3 0.1 5e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family Pkinase_Tyr PF07714.12 KKK24803.1 - 0.011 14.8 0.0 0.034 13.2 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KKK24803.1 - 0.039 13.1 0.0 0.082 12.0 0.0 1.6 1 1 0 1 1 1 0 Protein kinase domain TrkH PF02386.11 KKK24804.1 - 2.6e-103 345.3 3.1 2.6e-103 345.3 2.1 1.9 2 0 0 2 2 2 1 Cation transport protein Zip PF02535.17 KKK24804.1 - 0.049 12.6 1.7 0.15 11.0 0.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter SelP_N PF04592.9 KKK24804.1 - 0.69 9.2 6.5 1.1 8.5 4.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cytomega_TRL10 PF06084.6 KKK24805.1 - 2.1 8.1 7.2 0.65 9.7 2.1 2.1 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Metallophos_C PF14008.1 KKK24806.1 - 1.2e-09 38.0 1.1 9.1e-09 35.2 0.1 2.6 2 1 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 KKK24806.1 - 7.6e-07 28.7 0.3 0.0051 16.2 0.0 2.4 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase PhoD PF09423.5 KKK24806.1 - 0.019 13.5 0.1 0.26 9.7 0.0 2.0 1 1 1 2 2 2 0 PhoD-like phosphatase Methyltransf_2 PF00891.13 KKK24807.1 - 1.2e-32 113.0 0.0 4.2e-32 111.2 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase AA_permease_2 PF13520.1 KKK24808.1 - 6.1e-45 153.5 30.3 2e-26 92.5 12.5 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KKK24808.1 - 4.5e-09 35.1 30.8 4.7e-06 25.2 8.5 2.7 2 1 0 2 2 2 2 Amino acid permease MerC PF03203.9 KKK24808.1 - 2.8 8.3 14.5 7 7.0 0.8 4.3 2 2 2 4 4 4 0 MerC mercury resistance protein DUF914 PF06027.7 KKK24809.1 - 6.6e-100 334.2 18.3 8.3e-100 333.8 12.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KKK24809.1 - 0.00016 21.7 37.2 0.0041 17.1 10.1 2.8 2 1 1 3 3 3 2 EamA-like transporter family GPI-anchored PF10342.4 KKK24810.1 - 1.6e-23 82.9 0.1 1.6e-23 82.9 0.1 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KKK24810.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Methyltransf_11 PF08241.7 KKK24811.1 - 1.2e-15 57.7 0.0 3.5e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK24811.1 - 8.6e-13 48.6 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK24811.1 - 2.7e-11 43.7 0.0 5.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK24811.1 - 4.4e-11 42.7 0.0 1.1e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK24811.1 - 1.9e-10 40.5 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK24811.1 - 3.4e-10 40.4 0.0 6.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK24811.1 - 1.3e-07 31.6 0.0 3.6e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KKK24811.1 - 0.0049 15.9 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KKK24811.1 - 0.092 12.1 0.0 0.39 10.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.6 KKK24811.1 - 0.18 10.4 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) p450 PF00067.17 KKK24812.1 - 3e-55 187.5 0.0 1.3e-54 185.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KKK24813.1 - 5.3e-75 252.1 1.1 1.2e-74 251.0 0.7 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KKK24813.1 - 6.1e-38 129.3 0.1 1.7e-37 127.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KKK24813.1 - 3.2e-31 107.3 4.2 3.3e-15 56.1 0.5 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KKK24813.1 - 1.7e-26 93.0 0.0 3.4e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KKK24813.1 - 8.2e-25 87.7 0.0 8.8e-24 84.4 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.7 KKK24813.1 - 5.3e-19 68.5 0.0 1.6e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 KKK24813.1 - 1.9e-15 57.0 0.1 5.4e-12 45.7 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK24813.1 - 9.1e-13 48.1 0.2 9.7e-10 38.3 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 KKK24813.1 - 1.4e-11 44.2 0.0 4.6e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK24813.1 - 7.1e-11 42.0 0.0 4.4e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK24813.1 - 1.3e-10 41.5 0.0 6.2e-10 39.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 KKK24813.1 - 2.6e-10 39.8 0.0 4.7e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 Prolyl oligopeptidase family Methyltransf_18 PF12847.2 KKK24813.1 - 2.3e-08 34.6 0.0 2.1e-07 31.4 0.0 2.8 3 0 0 3 3 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 KKK24813.1 - 7e-08 32.6 6.6 1.8e-07 31.2 0.3 3.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_25 PF13649.1 KKK24813.1 - 9.6e-08 32.3 0.0 3.8e-07 30.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain DLH PF01738.13 KKK24813.1 - 3.6e-05 23.1 0.0 0.00057 19.2 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Thiolase_N PF00108.18 KKK24813.1 - 0.00012 21.1 0.1 0.00024 20.1 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 KKK24813.1 - 0.00021 21.2 0.0 0.00064 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KKK24813.1 - 0.00032 20.1 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 KKK24813.1 - 0.00044 19.4 0.0 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Abhydrolase_2 PF02230.11 KKK24813.1 - 0.0021 17.5 0.0 0.38 10.1 0.0 2.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Methyltransf_16 PF10294.4 KKK24813.1 - 0.0056 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase LIP PF03583.9 KKK24813.1 - 0.0066 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Secretory lipase COesterase PF00135.23 KKK24813.1 - 0.044 12.5 0.0 0.076 11.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_1 PF00561.15 KKK24813.1 - 0.067 12.7 2.0 0.17 11.4 0.2 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold RrnaAD PF00398.15 KKK24813.1 - 0.14 11.1 0.0 0.31 10.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GMC_oxred_N PF00732.14 KKK24814.1 - 1.9e-55 188.1 0.0 2.6e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK24814.1 - 5.5e-33 114.2 0.0 1.4e-32 113.0 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KKK24814.1 - 2e-06 27.9 0.1 0.034 14.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK24814.1 - 3.5e-06 26.1 1.1 5.8e-05 22.1 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KKK24814.1 - 1.1e-05 24.3 0.2 1.9e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.19 KKK24814.1 - 1.1e-05 24.4 1.7 0.0059 15.5 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KKK24814.1 - 0.0001 22.2 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK24814.1 - 0.00034 19.6 0.3 0.0035 16.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KKK24814.1 - 0.00063 19.7 0.1 0.0019 18.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK24814.1 - 0.0021 17.2 0.1 0.0072 15.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KKK24814.1 - 0.0079 15.9 0.1 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KKK24814.1 - 0.088 13.2 0.3 0.46 10.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK24814.1 - 0.13 10.7 0.1 0.21 10.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein ketoacyl-synt PF00109.21 KKK24815.1 - 7.2e-66 222.2 0.0 1.8e-65 220.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KKK24815.1 - 5.7e-61 205.3 1.6 1.2e-60 204.3 0.2 2.3 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KKK24815.1 - 6.6e-56 189.9 0.1 2.3e-55 188.1 0.1 1.9 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KKK24815.1 - 7e-50 169.8 0.0 2e-49 168.3 0.0 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KKK24815.1 - 4.1e-48 163.4 6.9 2.6e-47 160.8 0.1 3.4 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KKK24815.1 - 2.1e-39 134.0 0.0 6.1e-39 132.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KKK24815.1 - 7.9e-16 57.7 0.0 4.6e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KKK24815.1 - 3.6e-13 49.5 0.0 1.2e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KKK24815.1 - 6.3e-13 49.7 0.0 7.1e-12 46.3 0.0 2.9 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KKK24815.1 - 7.3e-12 45.6 0.0 1.1e-10 41.8 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 KKK24815.1 - 5.5e-06 26.5 0.7 1.4e-05 25.3 0.1 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KKK24815.1 - 7.8e-06 25.5 0.0 3.3e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK24815.1 - 6.5e-05 22.1 0.0 0.00016 20.8 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KKK24815.1 - 7.1e-05 23.3 0.1 0.003 18.1 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK24815.1 - 0.00013 22.3 0.0 0.0019 18.6 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.7 KKK24815.1 - 0.00014 21.5 0.2 0.00044 19.9 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.4 KKK24815.1 - 0.00041 19.8 0.0 0.002 17.5 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Shikimate_DH PF01488.15 KKK24815.1 - 0.029 14.4 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Kinesin-related PF06548.6 KKK24815.1 - 0.14 10.7 0.1 0.21 10.0 0.1 1.2 1 0 0 1 1 1 0 Kinesin-related Fungal_trans PF04082.13 KKK24816.1 - 4.1e-13 48.7 0.1 7.4e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24816.1 - 4.5e-09 36.0 11.2 8.6e-09 35.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-binding PF00249.26 KKK24817.1 - 1.2e-29 102.0 11.1 5.7e-10 39.0 0.3 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK24817.1 - 1.9e-25 88.7 6.9 1.7e-07 31.2 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KKK24817.1 - 0.15 12.2 1.0 2.8 8.1 0.1 2.9 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.1 KKK24817.1 - 1.1 9.1 4.4 24 4.9 0.5 3.9 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain Lactamase_B PF00753.22 KKK24818.1 - 3.6e-06 26.7 5.5 2.1e-05 24.2 3.8 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK24818.1 - 0.00031 20.3 0.1 0.00064 19.3 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KKK24818.1 - 0.034 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Phosphoesterase PF04185.9 KKK24819.1 - 1.4e-18 67.2 7.3 2.7e-17 63.0 0.7 2.9 2 1 1 3 3 3 3 Phosphoesterase family Sugar_tr PF00083.19 KKK24820.1 - 1.7e-24 86.2 26.8 1.8e-17 63.1 4.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK24820.1 - 9.5e-15 54.1 35.5 2.5e-08 33.0 13.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.15 KKK24820.1 - 0.83 8.9 4.7 8.9 5.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF21 Sugar_tr PF00083.19 KKK24821.1 - 2.7e-20 72.3 28.2 2.4e-18 65.9 19.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24821.1 - 2e-06 26.7 38.1 3.6e-05 22.6 7.7 3.2 2 2 1 3 3 3 2 Major Facilitator Superfamily DUF2333 PF10095.4 KKK24821.1 - 0.0014 17.3 0.0 0.0026 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2333) Transferase PF02458.10 KKK24822.1 - 6.5e-18 64.3 0.0 1.7e-14 53.1 0.0 2.9 3 0 0 3 3 3 3 Transferase family CIA30 PF08547.7 KKK24824.1 - 1e-37 129.4 0.0 1.2e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Amino_oxidase PF01593.19 KKK24825.1 - 6.1e-44 150.8 0.1 1e-26 94.0 0.0 2.7 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KKK24825.1 - 1.5e-15 56.9 0.3 2.8e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK24825.1 - 5.4e-07 29.9 0.3 1.5e-06 28.5 0.2 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK24825.1 - 1.8e-06 27.1 0.0 2.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KKK24825.1 - 2.4e-06 26.3 0.5 3.4e-06 25.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KKK24825.1 - 3.1e-06 26.3 0.0 4.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 KKK24825.1 - 7.8e-06 25.1 1.8 1.1e-05 24.6 0.8 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KKK24825.1 - 2e-05 24.7 0.0 3.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KKK24825.1 - 2.4e-05 23.9 0.0 4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KKK24825.1 - 9.3e-05 21.6 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK24825.1 - 0.00012 21.3 0.1 0.00033 19.8 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KKK24825.1 - 0.00017 21.5 0.1 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KKK24825.1 - 0.00043 19.2 0.7 0.00064 18.6 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KKK24825.1 - 0.0043 16.7 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KKK24825.1 - 0.03 13.2 0.4 0.042 12.7 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.15 KKK24825.1 - 0.034 14.2 0.5 0.078 13.0 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 KKK24825.1 - 0.043 12.4 0.4 0.073 11.6 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.1 KKK24825.1 - 0.095 12.9 1.4 0.13 12.5 0.4 1.8 2 1 0 2 2 1 0 Putative NAD(P)-binding ApbA PF02558.11 KKK24825.1 - 0.17 11.3 0.3 0.31 10.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 KKK24826.1 - 5.8e-31 107.4 19.1 5.8e-31 107.4 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YfhO PF09586.5 KKK24826.1 - 0.059 11.3 0.1 0.059 11.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial membrane protein YfhO PAP2_3 PF14378.1 KKK24827.1 - 1.3e-22 80.2 18.3 1.4e-19 70.3 2.4 2.6 3 0 0 3 3 3 2 PAP2 superfamily DUF4491 PF14898.1 KKK24827.1 - 1.6 8.9 5.8 0.7 10.0 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) PAP2 PF01569.16 KKK24827.1 - 2.2 7.9 10.9 1.3 8.7 5.5 2.2 1 1 1 2 2 2 0 PAP2 superfamily Sugar_tr PF00083.19 KKK24828.1 - 1.4e-26 93.0 28.3 5.8e-25 87.7 19.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24828.1 - 3e-14 52.5 71.1 1.3e-13 50.3 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KKK24829.1 - 4.6e-41 140.7 42.1 4.6e-41 140.7 29.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK24829.1 - 2.2e-14 52.6 14.2 3.2e-14 52.0 5.5 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 KKK24830.1 - 6.7e-46 156.7 0.0 9.6e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-bind_6 PF13921.1 KKK24831.1 - 3.3e-29 100.7 8.9 1.4e-12 47.5 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK24831.1 - 1.6e-28 98.4 15.5 7.5e-12 45.1 1.4 3.5 3 1 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KKK24831.1 - 0.29 11.3 8.6 9.2 6.5 0.0 3.3 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 KKK24831.1 - 3.2 7.7 6.2 1.7e+02 2.1 4.3 3.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Abhydrolase_6 PF12697.2 KKK24833.1 - 3.1e-07 30.4 0.0 1.3e-06 28.4 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family NACHT PF05729.7 KKK24833.1 - 1.9e-06 27.6 0.0 9.1e-05 22.1 0.0 2.8 1 1 0 1 1 1 1 NACHT domain Abhydrolase_5 PF12695.2 KKK24833.1 - 0.00031 20.5 0.0 0.0019 17.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KKK24833.1 - 0.00047 20.3 0.0 0.0026 17.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF676 PF05057.9 KKK24833.1 - 0.001 18.4 0.0 0.0025 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KKK24833.1 - 0.0028 17.2 0.0 0.007 15.9 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein RNA_helicase PF00910.17 KKK24833.1 - 0.0042 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KKK24833.1 - 0.024 14.3 0.0 0.37 10.5 0.0 2.8 3 0 0 3 3 3 0 Part of AAA domain Parvo_NS1 PF01057.12 KKK24833.1 - 0.025 13.4 0.0 0.085 11.7 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Abhydrolase_2 PF02230.11 KKK24833.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase KAP_NTPase PF07693.9 KKK24833.1 - 0.13 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain DUF2075 PF09848.4 KKK24833.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KKK24833.1 - 0.22 11.8 0.0 0.52 10.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 KKK24833.1 - 0.24 10.4 0.0 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 KaiC Abhydrolase_6 PF12697.2 KKK24834.1 - 2.3e-10 40.7 0.8 4.4e-10 39.8 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK24834.1 - 3.9e-06 26.6 0.0 5.1e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KKK24834.1 - 0.0034 16.0 0.0 0.0044 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 KKK24834.1 - 0.045 13.3 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold CALCOCO1 PF07888.6 KKK24834.1 - 0.16 10.2 0.1 0.25 9.5 0.0 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF377 PF04041.8 KKK24835.1 - 1.7e-44 151.7 0.0 2.3e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_43 PF04616.9 KKK24835.1 - 2.2e-08 33.5 2.2 0.00031 19.9 0.0 3.8 4 1 0 4 4 4 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KKK24835.1 - 2.3e-05 23.9 0.0 2.3e-05 23.9 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain AAA_16 PF13191.1 KKK24836.1 - 9.5e-07 28.9 0.3 3.4e-05 23.8 0.2 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK24836.1 - 0.00066 19.8 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KKK24836.1 - 0.0043 16.7 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 KKK24836.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KKK24836.1 - 0.013 15.0 0.1 0.39 10.1 0.1 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KKK24836.1 - 0.013 14.8 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KKK24836.1 - 0.019 15.1 0.0 0.058 13.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PEPCK_ATP PF01293.15 KKK24836.1 - 0.026 13.0 0.0 0.038 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase CPL PF08144.6 KKK24839.1 - 4.7e-16 58.9 1.1 5e-15 55.6 0.1 3.1 2 1 0 2 2 2 1 CPL (NUC119) domain Nop14 PF04147.7 KKK24839.1 - 0.01 13.8 22.2 0.019 12.9 15.4 1.4 1 0 0 1 1 1 0 Nop14-like family PUF PF00806.14 KKK24839.1 - 0.092 12.2 0.0 6.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat BUD22 PF09073.5 KKK24839.1 - 1.4 7.8 33.4 3.2 6.7 23.1 1.6 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.4 KKK24839.1 - 1.7 7.2 29.1 2.9 6.5 20.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glyco_hydro_72 PF03198.9 KKK24840.1 - 7.3e-130 432.5 10.5 8.4e-130 432.3 7.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 KKK24840.1 - 0.00091 18.2 0.2 0.0017 17.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF2406 PF10295.4 KKK24841.1 - 2.2e-18 66.5 0.2 2.5e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Sulfate_transp PF00916.15 KKK24842.1 - 1.9e-25 89.4 2.6 1.9e-25 89.4 1.8 1.5 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 KKK24842.1 - 2e-16 59.5 0.0 3.5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KKK24842.1 - 1.4e-09 37.3 0.1 2.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain Ceramidase PF05875.7 KKK24842.1 - 0.47 9.5 3.8 4.2 6.4 0.8 2.2 2 0 0 2 2 2 0 Ceramidase Sulfate_transp PF00916.15 KKK24843.1 - 1.8e-09 37.0 5.5 3.2e-09 36.2 3.8 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sld5 PF05916.6 KKK24844.1 - 8.2e-14 51.8 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.14 KKK24845.1 - 1.3e-12 47.7 1.6 2.9e-12 46.6 1.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 KKK24845.1 - 0.0096 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG_box_2 PF09011.5 KKK24845.1 - 0.031 14.6 1.1 0.073 13.4 0.8 1.7 1 0 0 1 1 1 0 HMG-box domain PUF PF00806.14 KKK24846.1 - 6.6e-60 195.3 4.7 2.7e-08 32.8 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 KKK24846.1 - 0.071 12.1 0.1 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) ORC5_C PF14630.1 KKK24847.1 - 1.5e-74 250.8 0.0 8.5e-41 140.1 0.0 2.1 2 0 0 2 2 2 2 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KKK24847.1 - 1.8e-13 50.8 0.1 3.7e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain WD40 PF00400.27 KKK24848.1 - 0.0032 17.3 5.9 0.52 10.2 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Kelch_2 PF07646.10 KKK24848.1 - 0.09 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Kelch motif E1-E2_ATPase PF00122.15 KKK24849.1 - 5.8e-62 208.7 8.6 5.8e-62 208.7 6.0 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KKK24849.1 - 7e-22 78.8 0.0 9.9e-21 75.1 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK24849.1 - 5.2e-12 46.3 0.0 1.1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK24849.1 - 1.1e-10 40.8 0.0 2.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK24849.1 - 0.0016 18.1 0.7 0.0029 17.2 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RabGAP-TBC PF00566.13 KKK24853.1 - 2.1e-34 118.8 3.9 2.2e-34 118.8 1.7 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SPX PF03105.14 KKK24853.1 - 0.039 13.7 0.3 0.045 13.5 0.2 1.3 1 1 0 1 1 1 0 SPX domain Gp-FAR-1 PF05823.7 KKK24853.1 - 0.095 12.6 0.7 0.17 11.8 0.5 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ribosomal_S5 PF00333.15 KKK24853.1 - 0.17 11.6 0.1 0.48 10.2 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Pkinase PF00069.20 KKK24854.1 - 1.9e-59 200.9 0.0 2.8e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24854.1 - 1.3e-20 73.6 0.0 2e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK24854.1 - 1.7e-06 27.2 0.0 3.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK24854.1 - 4.7e-05 23.2 0.1 0.0029 17.3 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KKK24854.1 - 8.2e-05 21.7 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KKK24854.1 - 0.00096 18.5 0.0 0.0024 17.2 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KKK24854.1 - 0.17 11.4 0.1 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase LRR_6 PF13516.1 KKK24855.1 - 5e-11 41.4 5.0 0.21 11.7 0.0 7.8 10 0 0 10 10 10 3 Leucine Rich repeat F-box-like PF12937.2 KKK24855.1 - 1.3e-10 40.7 0.0 4.8e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK24855.1 - 1.9e-09 36.9 0.5 1e-08 34.5 0.1 2.6 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.1 KKK24855.1 - 1.2e-05 24.9 4.0 0.34 10.6 0.0 4.3 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 KKK24855.1 - 0.00053 19.5 4.8 0.0082 15.7 0.0 4.5 4 2 0 4 4 4 1 Leucine Rich repeats (2 copies) Sugar_tr PF00083.19 KKK24855.1 - 0.026 13.1 0.1 0.037 12.5 0.1 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter LRR_1 PF00560.28 KKK24855.1 - 0.085 12.9 12.7 34 5.0 0.0 7.3 7 1 0 7 7 7 0 Leucine Rich Repeat Yippee-Mis18 PF03226.9 KKK24856.1 - 2.9e-24 84.9 2.3 3.3e-24 84.7 1.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 KKK24856.1 - 0.0015 18.5 0.7 0.098 12.6 0.0 2.2 1 1 1 2 2 2 1 HNH endonuclease DUF2039 PF10217.4 KKK24856.1 - 0.012 15.5 3.2 0.016 15.2 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Evr1_Alr PF04777.8 KKK24856.1 - 0.029 14.2 1.5 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family RIG-I_C-RD PF11648.3 KKK24856.1 - 0.041 13.7 1.6 0.094 12.5 1.1 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I DZR PF12773.2 KKK24856.1 - 0.16 11.8 1.7 0.23 11.2 0.3 1.9 2 1 0 2 2 2 0 Double zinc ribbon Endonuclease_7 PF02945.10 KKK24856.1 - 0.47 10.2 4.2 0.2 11.3 0.7 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII PTS_2-RNA PF01885.11 KKK24857.1 - 1.2e-70 236.6 0.0 1.9e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family WD40 PF00400.27 KKK24857.1 - 0.07 13.0 3.6 16 5.5 0.2 4.6 6 0 0 6 6 6 0 WD domain, G-beta repeat DUF1504 PF07399.6 KKK24857.1 - 0.22 10.1 0.0 0.33 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1504) Mito_fiss_reg PF05308.6 KKK24857.1 - 0.57 9.5 4.4 0.16 11.3 0.8 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF2361 PF10153.4 KKK24858.1 - 1.9e-37 127.9 10.5 1.9e-37 127.9 7.3 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) TMF_TATA_bd PF12325.3 KKK24858.1 - 0.00096 18.8 1.5 0.4 10.4 1.1 2.6 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding DUF2489 PF10675.4 KKK24858.1 - 0.038 13.6 0.4 0.038 13.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF4637 PF15470.1 KKK24858.1 - 0.44 10.1 6.5 6.5 6.3 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) ER_lumen_recept PF00810.13 KKK24859.1 - 1.8e-39 135.6 4.5 3.1e-39 134.8 3.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KKK24859.1 - 0.0067 15.9 0.0 0.0067 15.9 0.0 3.5 4 0 0 4 4 4 2 PQ loop repeat HlyIII PF03006.15 KKK24859.1 - 0.13 11.7 5.8 0.17 11.2 4.0 1.2 1 0 0 1 1 1 0 Haemolysin-III related Myb_DNA-bind_3 PF12776.2 KKK24860.1 - 0.015 15.8 5.0 0.66 10.6 0.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KKK24860.1 - 0.19 11.8 7.3 2 8.5 3.6 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain eRF1_1 PF03463.10 KKK24861.1 - 3.3e-47 159.3 0.0 5.2e-47 158.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KKK24861.1 - 7.4e-19 68.0 0.0 1.3e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 KKK24861.1 - 3.3e-18 66.3 0.0 5e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 RIO1 PF01163.17 KKK24862.1 - 0.048 13.0 0.3 0.064 12.5 0.2 1.2 1 0 0 1 1 1 0 RIO1 family DUF4551 PF15087.1 KKK24862.1 - 1 7.6 6.0 1.3 7.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Abhydrolase_6 PF12697.2 KKK24863.1 - 2.2e-33 116.0 0.0 2.5e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK24863.1 - 1.6e-20 73.3 0.4 6.8e-20 71.2 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK24863.1 - 2e-19 70.1 0.1 1.2e-15 57.7 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ndr PF03096.9 KKK24863.1 - 1.1e-08 33.8 0.0 1.9e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 KKK24863.1 - 1.9e-06 27.4 0.2 0.069 12.5 0.1 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KKK24863.1 - 5.1e-06 26.3 0.1 1.3e-05 24.9 0.1 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KKK24863.1 - 8.3e-06 25.1 0.0 0.04 13.1 0.0 2.2 1 1 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 KKK24863.1 - 0.0012 18.2 0.1 1.2 8.3 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family Ser_hydrolase PF06821.8 KKK24863.1 - 0.0017 17.9 0.2 0.024 14.2 0.0 2.1 1 1 0 2 2 2 1 Serine hydrolase Esterase PF00756.15 KKK24863.1 - 0.0031 16.9 0.5 0.014 14.8 0.4 1.9 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 KKK24863.1 - 0.0041 16.7 0.7 0.0084 15.7 0.2 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 KKK24863.1 - 0.0074 15.5 0.1 0.025 13.8 0.0 1.8 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KKK24863.1 - 0.0089 15.6 0.4 0.021 14.4 0.2 1.5 1 1 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 KKK24863.1 - 0.021 14.5 0.3 0.04 13.6 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.6 KKK24863.1 - 0.023 13.7 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.8 KKK24863.1 - 0.039 12.2 0.2 0.94 7.6 0.0 2.3 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Thioesterase PF00975.15 KKK24863.1 - 0.067 13.3 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Dioxygenase_C PF00775.16 KKK24864.1 - 8e-51 171.8 0.0 1.1e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KKK24864.1 - 1.5e-13 50.5 0.1 2.4e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KKK24864.1 - 2e-05 24.5 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KKK24864.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) Xpo1 PF08389.7 KKK24865.1 - 8.6e-23 80.8 0.0 9.2e-22 77.5 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KKK24865.1 - 0.00021 21.1 0.3 0.0033 17.2 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 KKK24865.1 - 0.055 13.7 0.0 0.28 11.5 0.0 2.2 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.17 KKK24865.1 - 0.076 13.1 0.3 12 6.2 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 KKK24865.1 - 0.082 13.4 1.5 0.88 10.1 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat Adaptin_N PF01602.15 KKK24865.1 - 0.12 10.6 0.6 0.52 8.5 0.1 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Nucleoporin_N PF08801.6 KKK24866.1 - 3.3e-88 296.2 0.1 3.9e-88 296.0 0.1 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Rot1 PF10681.4 KKK24867.1 - 1.8e-90 301.9 0.0 2.1e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.5 KKK24868.1 - 2.2e-19 69.7 1.7 2.6e-19 69.5 1.2 1.1 1 0 0 1 1 1 1 Yqey-like protein Cellulase PF00150.13 KKK24868.1 - 0.016 14.4 0.0 0.034 13.3 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) ParcG PF10274.4 KKK24868.1 - 0.031 14.1 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein LSM PF01423.17 KKK24869.1 - 1.4e-14 53.3 0.1 1.7e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain 5-FTHF_cyc-lig PF01812.15 KKK24870.1 - 2.7e-23 82.6 0.0 4.1e-23 82.1 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family TFIIA PF03153.8 KKK24873.1 - 0.37 10.6 8.6 0.064 13.1 1.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 KKK24875.1 - 2.7e-47 157.0 17.7 7e-12 44.7 0.1 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KKK24875.1 - 4.3e-09 35.0 3.7 0.11 10.6 0.0 4.7 4 1 0 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KKK24875.1 - 0.013 15.2 0.7 0.11 12.1 0.0 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KKK24875.1 - 0.037 12.2 0.0 0.082 11.1 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Hira PF07569.6 KKK24875.1 - 0.048 12.8 0.4 3.1 6.9 0.0 3.1 2 1 2 4 4 4 0 TUP1-like enhancer of split DUF1513 PF07433.6 KKK24875.1 - 0.19 10.5 0.9 4.7 6.0 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Tctex-1 PF03645.8 KKK24876.1 - 8.2e-34 115.5 0.0 9.5e-34 115.2 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 KKK24877.1 - 5.7e-12 45.6 4.9 5.7e-12 45.6 3.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 KKK24877.1 - 0.032 12.8 0.1 0.038 12.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1673 PF07895.6 KKK24877.1 - 0.092 12.2 0.2 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF2615 PF11027.3 KKK24877.1 - 0.2 11.6 0.7 0.34 10.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF4234 PF14018.1 KKK24877.1 - 0.21 11.3 1.1 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF4131 PF13567.1 KKK24877.1 - 4.4 6.6 6.7 2.3 7.6 2.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ketoacyl-synt PF00109.21 KKK24878.1 - 2.3e-58 197.6 1.6 2.5e-58 197.5 1.1 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 KKK24878.1 - 5.6e-05 22.2 0.0 8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Trypan_PARP PF05887.6 KKK24879.1 - 1.1 9.0 6.0 0.33 10.7 1.0 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Prp31_C PF09785.4 KKK24880.1 - 4.1e-46 156.4 0.7 8.7e-46 155.3 0.5 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KKK24880.1 - 4.5e-37 126.6 0.0 7.4e-37 125.9 0.0 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KKK24880.1 - 8.5e-13 47.9 0.1 1.7e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain TPR_14 PF13428.1 KKK24881.1 - 8.2e-23 78.8 14.8 0.002 18.5 0.0 11.6 6 2 6 12 12 12 4 Tetratricopeptide repeat HAT PF02184.11 KKK24881.1 - 3.7e-20 71.3 81.2 1.4e-13 50.2 4.2 13.3 14 0 0 14 14 14 6 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 KKK24881.1 - 3.3e-17 62.6 12.4 0.0094 16.6 0.0 8.5 9 1 2 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KKK24881.1 - 3.3e-15 56.1 0.4 0.00058 20.1 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat Suf PF05843.9 KKK24881.1 - 5e-15 55.9 20.8 2.9e-05 23.9 0.3 5.9 2 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.1 KKK24881.1 - 2.4e-09 36.6 0.5 0.24 11.6 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KKK24881.1 - 4.1e-08 32.7 2.6 0.85 9.3 0.0 6.4 6 1 1 7 7 7 3 TPR repeat TPR_12 PF13424.1 KKK24881.1 - 9.5e-07 28.6 14.4 0.018 14.9 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK24881.1 - 4.4e-06 26.2 15.4 0.12 12.3 0.0 8.2 10 0 0 10 10 9 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KKK24881.1 - 0.00026 20.6 27.8 0.12 12.2 1.4 6.7 5 1 1 6 6 6 2 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.1 KKK24881.1 - 0.011 16.0 15.5 3 8.5 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK24881.1 - 0.085 12.6 16.8 11 6.0 0.0 7.0 9 0 0 9 9 7 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KKK24881.1 - 0.15 10.9 30.7 1.3 7.8 0.1 6.6 2 2 1 4 4 4 0 NRDE-2, necessary for RNA interference TPR_1 PF00515.23 KKK24881.1 - 0.32 10.6 3.4 5.3 6.8 0.0 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat DNA_alkylation PF08713.6 KKK24921.1 - 0.0029 17.1 1.8 0.0041 16.6 1.2 1.2 1 0 0 1 1 1 1 DNA alkylation repair enzyme DUF755 PF05501.6 KKK24921.1 - 0.0065 16.5 3.9 0.0065 16.5 2.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF755) NST1 PF13945.1 KKK24921.1 - 0.094 12.7 8.9 0.18 11.8 6.2 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Pex14_N PF04695.8 KKK24921.1 - 0.59 10.1 10.5 0.45 10.5 1.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GCD14 PF08704.5 KKK24921.1 - 0.91 8.9 3.0 1.3 8.4 2.1 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit TP53IP5 PF15331.1 KKK24921.1 - 2 8.2 8.9 3.1 7.6 6.2 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DDHD PF02862.12 KKK24921.1 - 2.9 7.6 6.1 4.6 6.9 4.3 1.4 1 0 0 1 1 1 0 DDHD domain Mito_carr PF00153.22 KKK24922.1 - 5.8e-27 93.2 0.1 7e-26 89.7 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial carrier protein Peptidase_M22 PF00814.20 KKK24923.1 - 2.5e-45 155.0 0.0 1.1e-43 149.7 0.0 2.5 1 1 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.11 KKK24923.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain YycC PF14174.1 KKK24923.1 - 0.063 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 YycC-like protein Peptidase_C50 PF03568.12 KKK24924.1 - 3.6e-131 437.3 0.0 6.8e-131 436.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 Esterase PF00756.15 KKK24924.1 - 3.5e-53 180.6 0.0 7.4e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KKK24924.1 - 9.2e-05 22.2 0.0 0.00022 20.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family CHAT PF12770.2 KKK24924.1 - 0.00015 21.0 3.8 0.00043 19.4 0.0 3.2 5 0 0 5 5 5 1 CHAT domain Abhydrolase_6 PF12697.2 KKK24924.1 - 0.00019 21.3 0.0 0.0032 17.3 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPR_12 PF13424.1 KKK24924.1 - 0.00045 20.0 16.2 0.039 13.8 0.1 6.2 4 2 1 6 6 6 1 Tetratricopeptide repeat Esterase_phd PF10503.4 KKK24924.1 - 0.00058 19.1 0.0 0.0025 17.1 0.0 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KKK24924.1 - 0.0095 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 KKK24924.1 - 0.055 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) TPR_2 PF07719.12 KKK24924.1 - 0.065 13.1 11.3 2.4 8.2 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1980 PF09323.5 KKK24924.1 - 0.13 12.0 0.1 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) TPR_11 PF13414.1 KKK24924.1 - 0.16 11.6 3.9 17 5.1 0.0 4.4 3 1 1 4 4 4 0 TPR repeat AXE1 PF05448.7 KKK24924.1 - 0.26 9.7 0.0 0.47 8.8 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TPR_1 PF00515.23 KKK24924.1 - 0.7 9.5 2.6 20 5.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK24924.1 - 9.1 6.3 7.4 4.2 7.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.13 KKK24926.1 - 6.6e-08 32.3 9.3 6.6e-08 32.3 6.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.5 KKK24926.1 - 0.86 9.7 6.2 2.5 8.2 4.3 1.8 1 0 0 1 1 1 0 Opy2 protein Cu-oxidase_3 PF07732.10 KKK24927.1 - 1.6e-36 124.6 0.1 1.1e-35 121.8 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK24927.1 - 4.5e-33 113.6 1.8 3.1e-26 91.5 0.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK24927.1 - 7.6e-16 58.4 0.0 1.4e-14 54.3 0.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase VWA PF00092.23 KKK24929.1 - 3e-05 23.7 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KKK24929.1 - 4.8e-05 23.5 0.0 7.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KKK24929.1 - 0.012 15.2 0.0 0.033 13.8 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain Fungal_trans_2 PF11951.3 KKK24930.1 - 1.2e-58 198.5 1.2 1.6e-58 198.1 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24930.1 - 1.9e-08 34.0 11.2 3.3e-08 33.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hormone_recep PF00104.25 KKK24930.1 - 0.053 12.6 0.2 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Guanylate_kin PF00625.16 KKK24931.1 - 2e-20 72.9 0.0 2.2e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase DUF1895 PF08988.5 KKK24931.1 - 0.012 15.6 0.3 0.029 14.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1895) cwf21 PF08312.7 KKK24931.1 - 0.73 9.7 3.4 1.3 8.8 2.4 1.4 1 0 0 1 1 1 0 cwf21 domain Septin PF00735.13 KKK24932.1 - 1.5e-112 375.2 0.2 1.7e-112 375.0 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KKK24932.1 - 1.8e-06 27.8 0.0 3.8e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KKK24932.1 - 9.4e-06 24.8 0.0 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KKK24932.1 - 8.6e-05 21.7 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KKK24932.1 - 0.00024 20.5 0.2 0.019 14.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KKK24932.1 - 0.001 18.8 0.4 1.3 8.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 KKK24932.1 - 0.0018 17.8 0.2 0.0018 17.8 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 KKK24932.1 - 0.015 15.5 0.2 0.025 14.8 0.1 1.6 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 KKK24932.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 KKK24932.1 - 0.021 13.6 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 KKK24932.1 - 0.026 14.6 0.0 0.061 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 KKK24932.1 - 0.027 13.6 0.1 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KKK24932.1 - 0.031 14.2 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KKK24932.1 - 0.059 13.7 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KKK24932.1 - 0.07 13.6 0.0 0.19 12.2 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 KKK24932.1 - 0.076 11.8 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.2 KKK24932.1 - 0.11 11.5 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 WD40 PF00400.27 KKK24933.1 - 1.2e-31 107.3 17.9 1.4e-12 46.9 0.5 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_L32p PF01783.18 KKK24933.1 - 5.4e-13 48.9 6.8 1e-12 48.0 4.7 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family eIF2A PF08662.6 KKK24933.1 - 4.1e-06 26.6 0.0 0.014 15.0 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.4 KKK24933.1 - 0.00014 21.1 0.0 0.002 17.2 0.0 2.4 1 1 2 3 3 3 2 Lactonase, 7-bladed beta-propeller PQQ_2 PF13360.1 KKK24933.1 - 0.0034 16.8 1.0 0.016 14.7 0.6 2.1 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 KKK24933.1 - 0.0036 15.5 0.1 0.019 13.1 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KKK24933.1 - 0.0043 15.4 0.0 0.011 14.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.1 KKK24933.1 - 0.011 14.8 0.4 1.4 7.9 0.0 3.5 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Stc1 PF12898.2 KKK24933.1 - 0.072 13.1 0.4 0.16 12.0 0.2 1.5 1 1 0 1 1 1 0 Stc1 domain Complex1_LYR PF05347.10 KKK24934.1 - 9.3e-06 25.3 2.3 2.4e-05 24.0 1.6 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK24934.1 - 0.012 15.8 1.3 0.021 15.0 0.9 1.6 1 1 0 1 1 1 0 Complex1_LYR-like DUF2293 PF10056.4 KKK24935.1 - 3.1e-28 97.5 0.1 5.9e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) HMA PF00403.21 KKK24936.1 - 1.1e-15 57.4 0.7 1.3e-15 57.2 0.5 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Rrn6 PF10214.4 KKK24937.1 - 3e-208 693.6 0.5 3.4e-208 693.4 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 KKK24938.1 - 2.6e-22 78.5 0.4 1.1e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 SF-assemblin PF06705.6 KKK24938.1 - 0.017 14.2 8.3 0.024 13.8 5.8 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin AHS1 PF02682.11 KKK24938.1 - 0.064 12.7 1.3 0.12 11.8 0.9 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Polysacc_deac_1 PF01522.16 KKK24938.1 - 0.11 12.0 0.3 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Polysaccharide deacetylase Mnd1 PF03962.10 KKK24938.1 - 2.6 7.6 12.3 1.5 8.4 1.4 2.1 1 1 1 2 2 2 0 Mnd1 family Tcp11 PF05794.8 KKK24939.1 - 6.3e-50 170.1 0.0 1.6e-49 168.8 0.0 1.7 1 1 0 1 1 1 1 T-complex protein 11 PIN_4 PF13638.1 KKK24939.1 - 4.9 7.2 7.8 45 4.1 0.0 3.0 2 1 0 2 2 2 0 PIN domain zinc_ribbon_6 PF14599.1 KKK24940.1 - 3.3e-25 87.6 0.4 3.3e-25 87.6 0.2 3.5 3 0 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 KKK24940.1 - 1.2e-15 57.4 21.0 1.2e-15 57.4 14.5 4.4 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 KKK24940.1 - 2.3e-09 36.9 9.1 2.3e-09 36.9 6.3 3.9 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK24940.1 - 4.7e-08 32.5 6.9 4.7e-08 32.5 4.8 5.9 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK24940.1 - 2.1e-07 30.8 6.4 2.1e-07 30.8 4.4 5.5 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK24940.1 - 7.7e-06 25.5 6.9 7.7e-06 25.5 4.8 6.0 4 1 1 5 5 5 1 zinc-RING finger domain Nop14 PF04147.7 KKK24940.1 - 7.4 4.3 17.8 10 3.8 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 KKK24941.1 - 7.4e-37 123.9 11.6 7.6e-10 38.2 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KKK24941.1 - 0.0097 15.3 0.2 4.9 6.7 0.0 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 KKK24941.1 - 0.082 11.6 0.2 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Glyco_hydro_7 PF00840.15 KKK24942.1 - 3.1e-217 721.0 19.5 3.1e-217 721.0 13.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KKK24942.1 - 5.4e-14 51.5 11.1 5.4e-14 51.5 7.7 3.5 5 0 0 5 5 5 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KKK24942.1 - 2.1 8.4 8.9 0.21 11.6 2.7 2.0 2 0 0 2 2 2 0 Toxin 7 Cellulase PF00150.13 KKK24943.1 - 1.6e-55 188.2 0.2 2.9e-55 187.4 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KKK24943.1 - 4.9e-14 51.6 10.4 4.9e-14 51.6 7.2 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Fungal_trans PF04082.13 KKK24944.1 - 6.3e-21 74.4 1.8 1e-20 73.7 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK24944.1 - 2.4e-11 43.2 9.4 4.4e-05 23.5 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK24944.1 - 1.2e-09 37.7 9.3 5.3e-05 23.2 2.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK24944.1 - 2.3e-09 37.0 11.8 1.5e-07 31.3 3.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KKK24944.1 - 0.009 15.8 4.4 0.045 13.6 0.8 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-FPG_IleRS PF06827.9 KKK24944.1 - 0.12 12.0 2.2 0.85 9.3 1.5 2.3 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-C2HC_2 PF13913.1 KKK24944.1 - 0.35 10.5 5.3 0.21 11.3 0.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KKK24944.1 - 0.44 10.7 1.7 2.9 8.1 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1 PF03811.8 KKK24944.1 - 0.99 8.9 4.5 2.3 7.7 3.1 1.6 1 0 0 1 1 1 0 InsA N-terminal domain Glyco_hydro_28 PF00295.12 KKK24945.1 - 4.2e-111 371.0 18.7 4.9e-111 370.8 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2180 PF09947.4 KKK24945.1 - 0.056 13.2 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Ammonium_transp PF00909.16 KKK24946.1 - 1.1e-68 231.6 17.7 1.4e-68 231.1 12.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family TarH PF02203.10 KKK24946.1 - 0.022 14.5 0.6 0.039 13.7 0.0 1.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue Formyl_trans_N PF00551.14 KKK24947.1 - 8.6e-39 132.9 0.1 1.1e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 KKK24947.1 - 7.6e-09 34.8 0.0 2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KKK24947.1 - 1.5e-06 27.8 0.0 5.5e-06 26.0 0.0 2.0 2 1 1 3 3 3 1 ACT domain MFS_1 PF07690.11 KKK24948.1 - 6.2e-42 143.5 30.6 6.2e-42 143.5 21.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK24948.1 - 9e-08 30.7 7.6 1.2e-07 30.3 5.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK24948.1 - 4.3e-05 22.2 22.3 0.00023 19.8 15.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter APH PF01636.18 KKK24949.1 - 3.9e-10 39.8 0.0 1.7e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK24949.1 - 0.0094 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KKK24949.1 - 0.057 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain TauD PF02668.11 KKK24950.1 - 4.8e-54 183.7 0.1 5.8e-54 183.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sua5_yciO_yrdC PF01300.13 KKK24951.1 - 8.4e-13 47.9 0.0 2.2e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 Telomere recombination GDPD PF03009.12 KKK24952.1 - 4e-11 42.8 0.0 9.5e-11 41.6 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Aminotran_1_2 PF00155.16 KKK24976.1 - 1.3e-05 24.3 0.0 1.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DNA_pol_E_B PF04042.11 KKK24977.1 - 4.4e-38 130.6 0.0 5.9e-37 126.9 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Acetyltransf_3 PF13302.1 KKK24978.1 - 0.048 13.8 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_16 PF10294.4 KKK24980.1 - 1.1e-55 187.7 0.0 1.8e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KKK24980.1 - 2.5e-05 23.9 0.0 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK24980.1 - 0.0098 16.4 0.0 0.022 15.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK24980.1 - 0.043 13.1 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KKK24980.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 KKK24982.1 - 1.7e-14 54.1 0.3 3.2e-10 40.1 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KKK24982.1 - 2.5e-10 40.5 0.0 7.5e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK24982.1 - 0.00098 18.8 0.2 0.58 9.8 0.3 2.2 1 1 1 2 2 2 2 KR domain NAD_binding_10 PF13460.1 KKK24982.1 - 0.028 14.4 0.2 0.034 14.1 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding DNA_pol_viral_C PF00336.13 KKK24982.1 - 0.032 13.4 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain NMO PF03060.10 KKK24984.1 - 1.2e-74 251.4 0.3 1.4e-74 251.2 0.2 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KKK24984.1 - 4.6e-07 29.0 0.1 1.4e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KKK24984.1 - 0.00066 18.6 3.0 0.0011 17.8 2.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AP_endonuc_2 PF01261.19 KKK24984.1 - 0.036 13.3 0.0 0.074 12.3 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Glu_synthase PF01645.12 KKK24984.1 - 0.13 11.1 0.7 0.22 10.4 0.5 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Taxilin PF09728.4 KKK24985.1 - 4.8e-106 354.3 52.0 4.8e-106 354.3 36.0 1.5 1 1 0 1 1 1 1 Myosin-like coiled-coil protein DUF4201 PF13870.1 KKK24985.1 - 2.6 7.4 57.4 0.012 15.0 11.0 4.7 1 1 4 5 5 5 0 Domain of unknown function (DUF4201) M16C_assoc PF08367.6 KKK24986.1 - 2.8e-50 170.4 0.0 4.5e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KKK24986.1 - 6.8e-20 71.5 0.0 1e-08 35.1 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KKK24986.1 - 1.1e-09 38.2 0.0 6.3e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2076 PF09849.4 KKK24989.1 - 0.014 15.4 3.8 0.018 15.1 2.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Zip PF02535.17 KKK24989.1 - 0.17 10.8 0.3 0.21 10.5 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CoA_transf_3 PF02515.12 KKK24990.1 - 2.8e-51 173.5 0.0 3.5e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Sugar_tr PF00083.19 KKK24991.1 - 1.8e-81 274.0 30.2 2.3e-81 273.7 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24991.1 - 6.3e-11 41.5 45.1 9.6e-10 37.6 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KKK24992.1 - 6.4e-64 215.3 0.1 8.7e-64 214.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK24992.1 - 3.1e-05 24.0 12.0 0.00073 19.7 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK24992.1 - 0.00039 20.5 11.5 0.0011 19.0 0.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK24992.1 - 0.019 15.2 10.9 0.051 13.8 1.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain EF-hand_7 PF13499.1 KKK24993.1 - 2e-12 47.0 0.0 3.2e-08 33.5 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KKK24993.1 - 9.8e-11 40.6 0.1 0.0017 18.0 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KKK24993.1 - 8.9e-10 38.3 0.0 0.00014 21.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KKK24993.1 - 2.8e-08 32.4 0.0 0.056 12.7 0.0 3.7 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KKK24993.1 - 5.9e-07 29.0 0.1 0.00047 19.7 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair DUF3216 PF11505.3 KKK24993.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) UPF0154 PF03672.8 KKK24993.1 - 0.075 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 KKK24993.1 - 0.14 11.5 0.6 4.2 6.8 0.2 2.7 2 0 0 2 2 2 0 EF hand Shadoo PF14999.1 KKK24994.1 - 0.021 14.6 2.1 3.6 7.4 0.2 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective zf-DHHC PF01529.15 KKK24994.1 - 0.053 12.9 2.1 0.3 10.4 0.2 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase PBP1_TM PF14812.1 KKK24994.1 - 0.11 12.8 5.0 0.52 10.6 1.4 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Yippee-Mis18 PF03226.9 KKK24994.1 - 0.13 12.2 0.1 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Myc_N PF01056.13 KKK24994.1 - 0.18 10.9 9.3 0.044 12.9 2.3 2.1 2 0 0 2 2 2 0 Myc amino-terminal region TLP-20 PF06088.6 KKK24994.1 - 0.38 10.3 5.9 0.67 9.6 2.6 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nucleoplasmin PF03066.10 KKK24994.1 - 0.4 10.1 8.3 0.56 9.7 1.6 2.4 2 0 0 2 2 2 0 Nucleoplasmin Ribosomal_60s PF00428.14 KKK24994.1 - 0.52 10.7 16.1 2.1 8.7 1.8 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.5 KKK24994.1 - 1.1 9.5 9.3 0.96 9.7 2.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Daxx PF03344.10 KKK24994.1 - 1.5 7.2 10.0 0.12 10.8 2.3 2.1 2 0 0 2 2 2 0 Daxx Family Pex14_N PF04695.8 KKK24994.1 - 1.6 8.7 5.9 2.7 8.0 0.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1510 PF07423.6 KKK24994.1 - 1.9 7.8 9.6 1.3 8.3 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Sigma70_ner PF04546.8 KKK24994.1 - 3.9 7.0 10.0 12 5.4 4.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Pox_Ag35 PF03286.9 KKK24994.1 - 4.8 6.6 11.5 0.035 13.6 1.4 2.1 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Tim54 PF11711.3 KKK24994.1 - 8.6 4.8 8.6 0.71 8.3 2.6 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 MOSC PF03473.12 KKK24995.1 - 2.4e-11 43.2 0.1 1.9e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 MOSC domain MOSC_N PF03476.11 KKK24995.1 - 1.3e-09 37.8 0.0 3.2e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Rad51 PF08423.6 KKK24996.1 - 1.1e-10 40.8 0.0 6.4e-09 35.0 0.0 2.2 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KKK24996.1 - 1.5e-08 34.2 0.0 5.4e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 KKK24996.1 - 3.5e-06 26.3 0.0 5.9e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_10 PF12846.2 KKK24996.1 - 3.5e-06 26.6 0.0 4.1e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain KaiC PF06745.8 KKK24996.1 - 4.7e-06 25.8 0.0 9.8e-06 24.8 0.0 1.6 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.12 KKK24996.1 - 1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KKK24996.1 - 2.5e-05 24.4 0.0 8.8e-05 22.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 KKK24996.1 - 0.00019 21.6 0.1 0.00057 20.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 KKK24996.1 - 0.00035 19.5 0.0 0.015 14.2 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.1 KKK24996.1 - 0.0011 18.5 0.0 0.012 15.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.18 KKK24996.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 KKK24996.1 - 0.0015 18.2 0.4 0.0039 16.9 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain Arch_ATPase PF01637.13 KKK24996.1 - 0.0019 17.9 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 KKK24996.1 - 0.0023 18.7 0.0 0.012 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KKK24996.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KKK24996.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 KKK24996.1 - 0.022 14.9 0.0 0.37 10.9 0.0 2.5 2 1 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 KKK24996.1 - 0.039 12.8 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 KKK24996.1 - 0.048 13.5 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK24996.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain APS_kinase PF01583.15 KKK24996.1 - 0.053 13.1 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_35 PF14516.1 KKK24996.1 - 0.076 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 KKK24996.1 - 0.077 13.2 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_31 PF13614.1 KKK24996.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KKK24996.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein FA_desaturase PF00487.19 KKK24997.1 - 2.2e-19 69.9 11.4 2.2e-19 69.9 7.9 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KKK24997.1 - 8.8e-18 63.8 0.1 2.1e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Xan_ur_permease PF00860.15 KKK24998.1 - 4.3e-64 216.4 32.2 1.9e-63 214.2 22.3 1.8 1 1 0 1 1 1 1 Permease family RINGv PF12906.2 KKK24999.1 - 1.4e-09 37.8 3.8 3.2e-09 36.6 0.6 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 KKK24999.1 - 0.0099 15.6 3.8 0.026 14.3 0.8 2.2 2 0 0 2 2 2 1 Ring finger domain DUF1206 PF06724.6 KKK24999.1 - 0.058 13.1 0.5 0.058 13.1 0.3 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) PgaD PF13994.1 KKK24999.1 - 1.5 8.2 6.8 0.3 10.5 0.8 2.0 2 0 0 2 2 2 0 PgaD-like protein Amidohydro_2 PF04909.9 KKK25000.1 - 6.8e-38 130.7 0.2 5.9e-33 114.5 0.0 2.0 2 0 0 2 2 2 2 Amidohydrolase Proteasome PF00227.21 KKK25002.1 - 1.6e-56 190.6 0.0 4.4e-32 110.9 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KKK25002.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature S4 PF01479.20 KKK25011.1 - 1.3e-12 46.9 0.0 2.4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain Occludin_ELL PF07303.8 KKK25011.1 - 0.0079 16.9 0.1 0.016 15.9 0.1 1.5 1 0 0 1 1 1 1 Occludin homology domain PilP PF04351.8 KKK25011.1 - 0.05 13.4 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilP COG2 PF06148.6 KKK25011.1 - 0.077 12.8 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Evr1_Alr PF04777.8 KKK25012.1 - 1.1e-25 89.3 0.9 1.9e-25 88.6 0.6 1.3 1 0 0 1 1 1 1 Erv1 / Alr family DUF3504 PF12012.3 KKK25013.1 - 4.4 7.0 10.8 32 4.2 7.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3504) Adaptin_N PF01602.15 KKK25014.1 - 2.8e-148 494.5 5.9 3.5e-148 494.1 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KKK25014.1 - 2.9e-30 105.4 0.9 1.1e-26 93.7 0.1 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KKK25014.1 - 1.1e-20 73.6 1.6 5.9e-06 26.4 0.0 6.2 2 1 4 6 6 6 4 HEAT repeats HEAT PF02985.17 KKK25014.1 - 4.6e-12 44.9 3.8 0.016 15.2 0.0 7.2 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KKK25014.1 - 1.8e-05 25.0 0.2 2 9.0 0.0 6.4 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 KKK25014.1 - 0.00012 21.5 0.6 2 7.7 0.0 4.3 3 1 2 5 5 5 2 CLASP N terminal Arm PF00514.18 KKK25014.1 - 0.0014 18.3 0.9 8.3 6.4 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.3 KKK25014.1 - 0.042 13.4 0.3 0.15 11.7 0.1 2.1 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.4 KKK25014.1 - 0.072 12.8 0.0 1.7 8.3 0.0 2.9 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain ADH_N PF08240.7 KKK25015.1 - 5.4e-20 71.1 4.9 9.3e-20 70.4 3.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK25015.1 - 2.7e-16 59.3 0.0 4.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK25015.1 - 8.1e-07 29.9 0.0 1.5e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KKK25015.1 - 0.0035 16.5 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TBCC PF07986.7 KKK25016.1 - 2.3e-33 114.1 1.5 3e-33 113.7 0.6 1.6 2 0 0 2 2 2 1 Tubulin binding cofactor C Phytase-like PF13449.1 KKK25017.1 - 1.9e-28 99.6 0.0 7e-28 97.8 0.0 1.8 1 1 0 1 1 1 1 Esterase-like activity of phytase Trypan_PARP PF05887.6 KKK25017.1 - 0.0026 17.5 15.6 0.0026 17.5 10.8 2.6 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Coatomer_WDAD PF04053.9 KKK25019.1 - 1.6e-152 508.3 0.0 4.9e-152 506.7 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 KKK25019.1 - 6.7e-93 311.5 0.0 1.1e-92 310.8 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KKK25019.1 - 6.3e-51 168.5 11.1 2.9e-09 36.4 0.1 7.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KKK25019.1 - 0.015 13.4 6.8 1.7 6.6 0.5 3.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Clathrin PF00637.15 KKK25019.1 - 0.02 14.5 0.4 0.3 10.6 0.0 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS LysR_substrate PF03466.15 KKK25019.1 - 0.081 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 LysR substrate binding domain DUF2457 PF10446.4 KKK25019.1 - 0.22 10.2 0.1 0.35 9.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pro-kuma_activ PF09286.6 KKK25020.1 - 2.5e-41 141.0 0.7 4.8e-41 140.1 0.2 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KKK25020.1 - 4.9e-07 29.1 0.0 8.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Lyase_8_N PF08124.6 KKK25020.1 - 0.0052 15.7 0.0 0.0077 15.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain TLD PF07534.11 KKK25022.1 - 6.5e-17 61.8 0.0 7.6e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 TLD SAC3_GANP PF03399.11 KKK25023.1 - 9.8e-26 90.5 0.0 1.2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KKK25023.1 - 6.6e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 WD40 PF00400.27 KKK25024.1 - 0.00061 19.5 0.4 1.2 9.1 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Vps51 PF08700.6 KKK25025.1 - 4.4e-27 93.7 0.0 1.1e-26 92.5 0.0 1.7 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 KKK25025.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Sec5 PF15469.1 KKK25025.1 - 0.0095 15.6 0.0 0.023 14.4 0.0 1.6 1 1 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.7 KKK25025.1 - 0.03 12.7 0.0 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family THUMP PF02926.12 KKK25025.1 - 0.039 13.8 0.3 0.062 13.1 0.2 1.3 1 0 0 1 1 1 0 THUMP domain DUF1767 PF08585.7 KKK25026.1 - 1.4e-19 70.1 0.2 2.1e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 KKK25027.1 - 1.9e-39 133.0 38.0 9.1e-05 22.0 0.1 12.9 13 1 1 14 14 12 10 TPR repeat TPR_16 PF13432.1 KKK25027.1 - 4.3e-27 94.1 38.4 2.1e-05 25.0 0.0 12.1 9 2 3 12 12 12 8 Tetratricopeptide repeat TPR_17 PF13431.1 KKK25027.1 - 7.8e-24 81.8 11.5 0.2 11.9 0.0 15.1 16 0 0 16 16 16 4 Tetratricopeptide repeat TPR_14 PF13428.1 KKK25027.1 - 9.5e-21 72.4 35.6 0.094 13.4 0.0 16.2 15 6 5 20 20 16 5 Tetratricopeptide repeat TPR_12 PF13424.1 KKK25027.1 - 6.2e-20 70.9 24.7 8e-08 32.1 0.3 10.7 7 3 2 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 KKK25027.1 - 4.8e-18 63.9 30.5 0.014 14.9 0.0 14.6 16 2 1 17 17 17 5 Tetratricopeptide repeat TPR_2 PF07719.12 KKK25027.1 - 3.3e-17 60.9 53.7 0.062 13.2 0.1 15.8 19 0 0 19 19 16 7 Tetratricopeptide repeat TPR_19 PF14559.1 KKK25027.1 - 4e-17 62.3 13.7 0.013 15.8 0.0 10.2 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK25027.1 - 1.5e-14 52.5 14.4 0.13 12.1 0.1 12.1 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 KKK25027.1 - 4.7e-07 29.1 21.5 0.0016 18.1 0.0 10.7 13 1 0 13 13 12 2 Tetratricopeptide repeat TPR_6 PF13174.1 KKK25027.1 - 1.3e-06 28.5 22.3 0.21 12.1 0.1 10.9 14 0 0 14 14 11 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK25027.1 - 0.00012 22.1 17.9 0.02 15.0 0.0 7.1 5 3 4 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 KKK25027.1 - 0.0014 17.9 0.1 0.019 14.2 0.0 2.6 2 0 0 2 2 2 1 Coatomer epsilon subunit DUF2225 PF09986.4 KKK25027.1 - 0.0019 17.6 1.6 0.49 9.8 0.1 3.5 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 KKK25027.1 - 0.0023 17.7 17.7 0.35 10.8 0.1 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_4 PF07721.9 KKK25027.1 - 0.068 13.6 9.6 29 5.4 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Cellulase PF00150.13 KKK25028.1 - 8.3e-10 38.3 1.3 2.8e-08 33.3 0.6 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Xpo1 PF08389.7 KKK25029.1 - 2.3e-09 37.2 7.4 1.5e-08 34.7 1.0 4.5 4 2 1 5 5 5 1 Exportin 1-like protein HEAT_2 PF13646.1 KKK25029.1 - 0.0002 21.5 0.4 0.0074 16.5 0.0 3.6 4 0 0 4 4 4 1 HEAT repeats Arabinose_trans PF04602.7 KKK25029.1 - 0.064 11.4 0.0 0.099 10.8 0.0 1.2 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein GRIM-19 PF06212.7 KKK25030.1 - 4.9e-21 74.7 0.1 1e-20 73.7 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 KKK25031.1 - 2.5e-31 108.7 0.0 9.1e-31 106.8 0.0 1.9 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VID27 PF08553.5 KKK25032.1 - 0 1168.8 0.5 0 1168.7 0.3 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nop14 PF04147.7 KKK25032.1 - 3.4 5.4 16.0 6.1 4.6 11.1 1.3 1 0 0 1 1 1 0 Nop14-like family Thr_synth_N PF14821.1 KKK25033.1 - 1.6e-30 104.9 0.0 1e-29 102.3 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KKK25033.1 - 8.5e-16 58.0 0.0 2.8e-15 56.3 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glucan_synthase PF02364.10 KKK25034.1 - 0 1503.1 0.0 0 1502.7 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KKK25034.1 - 5.1e-24 84.4 0.2 1.4e-23 83.0 0.2 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 KKK25035.1 - 3.6e-39 134.7 0.0 4.5e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_17 PF00332.13 KKK25036.1 - 1.3e-07 30.9 0.8 2.4e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Laminin_II PF06009.7 KKK25037.1 - 0.023 14.4 5.5 1 9.1 1.2 2.4 2 0 0 2 2 2 0 Laminin Domain II Reo_sigmaC PF04582.7 KKK25037.1 - 0.075 12.1 1.3 0.42 9.7 1.1 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Jnk-SapK_ap_N PF09744.4 KKK25037.1 - 0.42 10.5 15.2 1.7 8.6 6.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Phage_GP20 PF06810.6 KKK25037.1 - 1.2 8.5 8.0 0.37 10.2 0.2 2.9 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF948 PF06103.6 KKK25037.1 - 1.2 9.0 4.5 27 4.7 0.3 3.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.6 KKK25037.1 - 2.5 8.5 9.6 4.9 7.6 0.4 3.6 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Adeno_PIX PF03955.9 KKK25037.1 - 7.9 7.0 7.6 6.6 7.3 0.1 3.2 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) COG6 PF06419.6 KKK25038.1 - 1.6e-243 809.4 0.3 1.8e-243 809.2 0.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Tnp_DNA_bind PF14706.1 KKK25038.1 - 0.051 13.2 0.1 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 Transposase DNA-binding NIF3 PF01784.13 KKK25039.1 - 1.1e-40 139.7 0.0 4.1e-38 131.3 0.0 2.0 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) NAD-GH PF10712.4 KKK25039.1 - 0.15 10.3 0.0 0.21 9.8 0.0 1.1 1 0 0 1 1 1 0 NAD-specific glutamate dehydrogenase Glyco_hydro_72 PF03198.9 KKK25040.1 - 2.9e-129 430.5 4.6 3.7e-129 430.2 3.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KKK25040.1 - 9.9e-22 77.2 5.6 9.9e-22 77.2 3.9 2.1 2 0 0 2 2 2 1 X8 domain SprT-like PF10263.4 KKK25041.1 - 4.5e-52 175.8 0.3 7.3e-52 175.1 0.2 1.3 1 0 0 1 1 1 1 SprT-like family DUF4448 PF14610.1 KKK25041.1 - 0.0086 15.5 0.6 0.016 14.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Peptidase_MA_2 PF13485.1 KKK25041.1 - 0.011 15.7 0.1 0.042 13.8 0.0 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M30 PF10460.4 KKK25041.1 - 0.07 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M30 Mog1 PF04603.7 KKK25042.1 - 2.2e-16 60.0 0.1 2.6e-11 43.6 0.0 3.1 1 1 1 2 2 2 2 Ran-interacting Mog1 protein NYN PF01936.13 KKK25042.1 - 0.00016 22.0 0.0 0.001 19.4 0.0 2.4 3 1 0 3 3 3 1 NYN domain WWbp PF10349.4 KKK25042.1 - 0.27 12.1 2.2 22 5.9 0.0 2.8 3 0 0 3 3 3 0 WW-domain ligand protein HSP9_HSP12 PF04119.7 KKK25043.1 - 5e-29 100.1 9.4 2.4e-28 97.9 6.5 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 Tombus_movement PF05318.7 KKK25043.1 - 0.024 15.2 2.3 0.027 15.0 1.4 1.3 1 1 0 1 1 1 0 Tombusvirus movement protein YtxH PF12732.2 KKK25043.1 - 0.24 11.8 2.1 0.37 11.1 1.5 1.5 1 1 0 1 1 1 0 YtxH-like protein LSM PF01423.17 KKK25044.1 - 8.8e-06 25.1 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Arm PF00514.18 KKK25045.1 - 1.7e-68 224.2 30.4 6.5e-13 47.9 0.1 11.3 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KKK25045.1 - 1.8e-23 82.6 14.2 7e-07 29.4 0.3 7.5 3 3 2 6 6 6 5 HEAT repeats HEAT PF02985.17 KKK25045.1 - 6e-20 69.4 14.7 0.047 13.7 0.1 9.7 10 0 0 10 10 9 5 HEAT repeat HEAT_EZ PF13513.1 KKK25045.1 - 2.3e-16 59.7 12.4 0.078 13.4 0.1 8.5 8 2 1 9 9 9 5 HEAT-like repeat KAP PF05804.7 KKK25045.1 - 1.2e-10 39.9 0.7 2.4e-10 39.0 0.5 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 KKK25045.1 - 1.7e-10 40.4 7.7 0.0034 16.5 0.0 3.3 2 1 1 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 KKK25045.1 - 2.6e-10 39.2 8.5 2.3e-06 26.2 0.5 2.8 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.9 KKK25045.1 - 5.3e-09 35.6 2.0 0.0012 18.0 0.7 3.1 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 KKK25045.1 - 0.01 15.7 3.5 6.5 6.6 0.1 4.5 2 1 5 7 7 7 0 V-ATPase subunit H RIX1 PF08167.7 KKK25045.1 - 0.011 15.3 0.3 0.21 11.2 0.2 2.9 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 KKK25045.1 - 0.012 16.0 8.1 12 6.7 0.3 6.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 KKK25045.1 - 0.023 15.0 0.2 1.8 8.9 0.1 3.4 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.4 KKK25045.1 - 0.11 10.7 7.7 0.7 8.0 2.2 2.7 1 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit Atx10homo_assoc PF09759.4 KKK25045.1 - 0.83 9.4 4.5 12 5.6 0.0 3.9 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain EXOSC1 PF10447.4 KKK25046.1 - 3.9e-28 97.2 0.2 5.9e-28 96.6 0.2 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KKK25046.1 - 6.7e-13 47.6 0.1 1.1e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CRISPR_Cse2 PF09485.5 KKK25046.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) EFG_C PF00679.19 KKK25047.1 - 2.5e-07 30.4 0.0 4.9e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 Elongation factor G C-terminus AA_permease_2 PF13520.1 KKK25048.1 - 3e-54 184.1 50.1 3.8e-54 183.8 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK25048.1 - 3.3e-22 78.4 39.3 4.5e-22 78.0 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2708 PF10917.3 KKK25049.1 - 1.3 8.8 0.1 1.3 8.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2708) AA_permease_2 PF13520.1 KKK25050.1 - 1.3e-45 155.7 48.7 3.7e-45 154.2 33.8 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK25050.1 - 9.5e-23 80.2 34.2 1.7e-22 79.4 23.7 1.4 1 0 0 1 1 1 1 Amino acid permease Meleagrin PF08189.6 KKK25051.1 - 0.0056 16.1 1.3 0.0056 16.1 0.9 2.2 2 0 0 2 2 2 1 Meleagrin/Cygnin family Bac_rhamnosid PF05592.6 KKK25052.1 - 1.5e-146 488.5 0.0 9.3e-96 321.0 0.0 2.2 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KKK25052.1 - 3.2e-50 170.0 1.0 2.6e-47 160.5 0.7 2.4 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Pro-kuma_activ PF09286.6 KKK25053.1 - 2.6e-36 124.8 0.0 6.8e-36 123.4 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KKK25053.1 - 6.1e-11 41.9 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DNA_pol_A_exo1 PF01612.15 KKK25054.1 - 3e-12 46.3 0.0 8.2e-12 44.9 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Dioxygenase_C PF00775.16 KKK25054.1 - 2.1e-09 36.8 0.0 4.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase SE PF08491.5 KKK25055.1 - 5.5e-95 317.3 0.0 6.8e-95 317.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KKK25055.1 - 6.4e-08 31.8 0.7 1.2e-05 24.4 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK25055.1 - 4.4e-07 29.2 0.1 0.00038 19.6 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 KKK25055.1 - 0.00054 18.9 0.2 0.029 13.2 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KKK25055.1 - 0.00096 19.1 0.6 0.0022 17.9 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK25055.1 - 0.0021 18.3 0.3 0.0046 17.3 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK25055.1 - 0.0022 17.1 0.4 0.0089 15.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 KKK25055.1 - 0.0024 17.0 0.8 0.0034 16.5 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK25055.1 - 0.0059 15.4 2.0 0.011 14.6 1.3 1.4 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KKK25055.1 - 0.012 14.5 0.6 0.045 12.6 0.3 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 KKK25055.1 - 0.037 12.5 0.3 0.065 11.6 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KKK25055.1 - 0.056 13.0 0.2 0.094 12.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KKK25055.1 - 0.063 13.1 0.2 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KKK25055.1 - 0.072 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KKK25055.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.14 KKK25055.1 - 0.11 11.5 0.5 7 5.7 0.1 2.3 2 0 0 2 2 2 0 GMC oxidoreductase ThiF PF00899.16 KKK25055.1 - 0.24 11.2 1.4 0.44 10.3 1.0 1.4 1 0 0 1 1 1 0 ThiF family PAP_assoc PF03828.14 KKK25056.1 - 2.1e-17 62.8 0.1 4.6e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KKK25056.1 - 3.2e-06 27.3 0.0 5.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ferrochelatase PF00762.14 KKK25057.1 - 9.4e-93 310.6 0.0 1.1e-92 310.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase PPR_3 PF13812.1 KKK25058.1 - 3.3e-09 36.2 1.5 0.0039 17.3 0.0 6.3 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 KKK25058.1 - 8.6e-05 22.2 1.2 1.1 9.4 0.0 5.4 6 0 0 6 6 6 1 PPR repeat PPR_2 PF13041.1 KKK25058.1 - 0.00019 21.3 0.2 4.8 7.2 0.0 4.6 4 1 0 4 4 4 1 PPR repeat family RPN7 PF10602.4 KKK25058.1 - 0.047 13.0 0.1 0.098 12.0 0.1 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 RHSP PF07999.6 KKK25058.1 - 0.048 12.2 0.0 0.3 9.6 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon hot spot protein RC-P840_PscD PF10657.4 KKK25058.1 - 0.086 12.6 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Photosystem P840 reaction centre protein PscD TPR_11 PF13414.1 KKK25058.1 - 0.11 12.1 0.2 0.33 10.6 0.2 1.8 1 0 0 1 1 1 0 TPR repeat Ku PF02735.11 KKK25059.1 - 2.5e-34 118.4 0.0 4e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KKK25059.1 - 3.5e-34 118.1 0.0 4.6e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KKK25059.1 - 3e-14 53.3 1.7 9.8e-14 51.6 1.2 1.9 1 1 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA PF00092.23 KKK25059.1 - 0.0015 18.2 0.0 0.004 16.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L5_C PF00673.16 KKK25060.1 - 7.7e-27 92.8 0.0 1.8e-26 91.6 0.0 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Pep3_Vps18 PF05131.9 KKK25061.1 - 8.4e-47 158.2 0.0 2.3e-46 156.8 0.0 1.8 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KKK25061.1 - 1e-10 41.3 2.8 7e-05 22.4 0.0 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KKK25061.1 - 0.0026 17.5 0.4 0.0065 16.2 0.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KKK25061.1 - 0.0049 16.5 0.3 0.013 15.2 0.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.4 KKK25061.1 - 0.018 15.1 0.5 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF1664 PF07889.7 KKK25061.1 - 0.024 14.4 1.5 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Vps39_2 PF10367.4 KKK25061.1 - 0.029 14.5 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF3849 PF12960.2 KKK25061.1 - 0.05 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) zf-C3HC4 PF00097.20 KKK25061.1 - 0.17 11.5 0.2 0.53 9.9 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH_1 PF13423.1 KKK25062.1 - 4.3e-73 246.3 0.0 9.8e-73 245.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 KKK25062.1 - 3.1e-14 52.7 0.0 5.9e-14 51.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EnY2 PF10163.4 KKK25062.1 - 0.088 12.7 0.1 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Transcription factor e(y)2 Peptidase_M16 PF00675.15 KKK25063.1 - 7.3e-22 77.7 0.0 1.6e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KKK25063.1 - 5.1e-17 62.1 0.0 9.9e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 KKK25064.1 - 6.9e-24 84.7 0.0 1.8e-21 76.8 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KKK25064.1 - 1.3e-15 57.0 1.3 5.2e-09 35.8 0.0 3.7 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KKK25064.1 - 3.9e-07 29.5 0.3 0.00034 20.0 0.1 2.5 2 0 0 2 2 2 2 TFIIE alpha subunit HLH PF00010.21 KKK25065.1 - 3.6e-16 58.6 0.3 7.3e-16 57.6 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CorA PF01544.13 KKK25079.1 - 7.4e-08 31.7 0.1 1e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sec39 PF08314.6 KKK25079.1 - 0.13 10.1 0.1 0.18 9.6 0.1 1.1 1 0 0 1 1 1 0 Secretory pathway protein Sec39 MFS_1 PF07690.11 KKK25096.1 - 6.8e-38 130.2 49.6 1.4e-37 129.2 31.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK25096.1 - 7.1e-13 47.6 15.2 7.1e-13 47.6 10.5 1.8 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK25096.1 - 3.7e-07 29.0 15.1 3.7e-07 29.0 10.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter RTA1 PF04479.8 KKK25097.1 - 2.7e-33 115.3 5.1 5.5e-33 114.3 3.6 1.4 1 1 0 1 1 1 1 RTA1 like protein DUF3382 PF11862.3 KKK25097.1 - 0.054 13.4 1.5 0.16 11.8 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) FAD_binding_3 PF01494.14 KKK25098.1 - 3.9e-16 59.0 0.5 1.6e-11 43.8 0.5 2.4 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 KKK25098.1 - 0.0028 16.5 0.0 0.034 12.9 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 KKK25098.1 - 0.0073 15.2 0.2 0.17 10.7 0.0 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KKK25098.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KKK25098.1 - 0.13 10.7 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.20 KKK25099.1 - 3.9e-19 69.1 0.0 1.2e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK25099.1 - 1.3e-07 31.4 0.0 0.00065 19.4 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KKK25099.1 - 3.1e-06 27.1 0.0 0.0007 19.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Peptidase_S29 PF02907.10 KKK25099.1 - 0.11 12.0 0.3 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease AreA_N PF07573.6 KKK25100.1 - 1.1e-23 83.6 2.3 1.1e-23 83.6 1.6 3.8 3 0 0 3 3 3 1 Nitrogen regulatory protein AreA N terminus GATA PF00320.22 KKK25100.1 - 3.5e-16 58.2 1.9 7.1e-16 57.2 1.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KKK25100.1 - 7.6e-14 50.9 3.9 1.5e-13 50.0 2.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ipi1_N PF12333.3 KKK25101.1 - 8e-25 86.7 1.4 1.5e-24 85.8 0.1 2.0 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 KKK25101.1 - 0.051 13.8 1.1 0.12 12.6 0.4 1.9 1 1 1 2 2 2 0 HEAT repeats HEAT PF02985.17 KKK25101.1 - 0.21 11.7 1.3 12 6.2 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat Zn_clus PF00172.13 KKK25102.1 - 1.9e-06 27.6 8.7 2.8e-06 27.1 6.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 KKK25103.1 - 4.4e-11 42.4 0.0 8.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK25103.1 - 3.5e-06 26.7 1.3 3.8e-05 23.3 0.1 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KKK25103.1 - 0.00084 20.2 0.0 0.0025 18.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AMP-binding PF00501.23 KKK25104.1 - 8.7e-82 274.7 0.6 2.8e-81 273.0 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KKK25104.1 - 3.1e-74 249.6 0.0 6.4e-74 248.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK25104.1 - 4.5e-50 170.7 0.1 9.3e-50 169.7 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KKK25104.1 - 6.3e-50 169.3 0.7 7.5e-49 165.8 0.1 3.0 3 0 0 3 3 2 1 KR domain PS-DH PF14765.1 KKK25104.1 - 1.2e-43 149.4 0.2 1.9e-43 148.7 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 KKK25104.1 - 1.7e-41 142.0 0.0 3.4e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 KKK25104.1 - 5.1e-41 140.3 0.2 3.1e-39 134.5 0.0 3.2 3 0 0 3 3 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KKK25104.1 - 6.2e-32 110.4 0.1 2.1e-31 108.7 0.0 1.9 3 0 0 3 3 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KKK25104.1 - 8e-30 103.1 0.0 2.1e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KKK25104.1 - 1.8e-21 76.4 0.2 9.9e-21 74.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KKK25104.1 - 1.5e-15 57.1 0.3 3.8e-06 27.0 0.2 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KKK25104.1 - 7.1e-14 52.0 0.1 3.5e-13 49.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK25104.1 - 2.1e-12 47.0 0.0 5.9e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK25104.1 - 1.3e-11 44.2 0.0 4.3e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain HxxPF_rpt PF13745.1 KKK25104.1 - 6.4e-11 42.4 0.1 3.3e-10 40.1 0.0 2.4 2 0 0 2 2 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 KKK25104.1 - 1.6e-09 38.3 0.0 8.7e-09 35.9 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK25104.1 - 6.2e-09 35.3 0.0 1.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KKK25104.1 - 2e-07 31.2 0.0 7.2e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KKK25104.1 - 2.6e-07 29.9 0.2 1.9e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Epimerase PF01370.16 KKK25104.1 - 7.6e-07 28.8 0.0 2.6e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NodS PF05401.6 KKK25104.1 - 3.3e-05 23.3 0.0 6.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 KKK25104.1 - 0.0016 17.5 0.0 0.0098 14.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 KKK25104.1 - 0.0069 15.8 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase NUMOD1 PF07453.8 KKK25104.1 - 0.32 10.8 0.0 0.84 9.5 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain zf-BED PF02892.10 KKK25111.1 - 0.0047 16.6 0.4 0.0047 16.6 0.3 1.8 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.13 KKK25111.1 - 0.015 15.2 6.9 0.035 14.0 4.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_B_palm PF14792.1 KKK25112.1 - 1.4e-31 108.8 0.0 3.2e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KKK25112.1 - 6.1e-21 73.8 0.0 1.1e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 KKK25112.1 - 5.4e-20 70.6 0.2 6e-19 67.3 0.1 2.4 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KKK25112.1 - 3e-17 62.5 0.1 7.7e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KKK25112.1 - 0.01 16.1 0.0 0.029 14.7 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH PF00633.18 KKK25112.1 - 0.063 13.0 0.7 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif DBP10CT PF08147.7 KKK25112.1 - 0.065 13.0 1.2 0.13 12.0 0.8 1.5 1 0 0 1 1 1 0 DBP10CT (NUC160) domain DUF4110 PF13422.1 KKK25112.1 - 0.097 12.5 1.5 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) CwfJ_C_1 PF04677.10 KKK25113.1 - 2.2e-30 104.8 0.0 4e-29 100.7 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KKK25113.1 - 3.8e-23 81.8 0.0 2.1e-22 79.4 0.0 2.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 2-Hacid_dh_C PF02826.14 KKK25114.1 - 1.8e-23 82.5 0.0 2.9e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK25114.1 - 1.1e-09 37.8 0.0 1.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KKK25114.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KKK25114.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KKK25114.1 - 0.099 13.0 0.0 0.27 11.6 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_S8 PF00082.17 KKK25115.1 - 2.5e-44 151.5 15.7 3.7e-44 150.9 10.9 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KKK25115.1 - 1.5e-16 60.6 0.2 2.9e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 NUP PF06516.6 KKK25116.1 - 1.5e-78 263.8 4.4 4.1e-55 186.8 1.6 2.3 1 1 1 2 2 2 2 Purine nucleoside permease (NUP) ATP_bind_1 PF03029.12 KKK25117.1 - 1.9e-77 260.0 0.0 3.1e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KKK25117.1 - 8.9e-05 21.9 0.0 0.005 16.2 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KKK25117.1 - 9.5e-05 21.9 0.8 0.00049 19.6 0.6 2.0 1 1 0 1 1 1 1 AAA-like domain ArgK PF03308.11 KKK25117.1 - 0.00013 20.8 0.0 0.03 13.0 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 KKK25117.1 - 0.00032 20.7 0.1 0.033 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK25117.1 - 0.00038 20.5 0.0 0.0014 18.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 KKK25117.1 - 0.001 18.7 0.0 0.0041 16.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 KKK25117.1 - 0.0012 18.8 0.0 0.0034 17.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KKK25117.1 - 0.0029 17.5 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KKK25117.1 - 0.0035 17.8 0.0 3.9 7.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 KKK25117.1 - 0.0063 17.3 0.1 0.031 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 KKK25117.1 - 0.01 15.0 0.0 0.21 10.8 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B Arf PF00025.16 KKK25117.1 - 0.013 14.7 0.0 3 7.0 0.0 3.2 3 0 0 3 3 3 0 ADP-ribosylation factor family NB-ARC PF00931.17 KKK25117.1 - 0.015 14.1 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 KKK25117.1 - 0.039 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 KKK25117.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.14 KKK25117.1 - 0.043 13.2 0.0 1.7 8.0 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 KKK25117.1 - 0.045 13.1 0.0 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Methyltransf_32 PF13679.1 KKK25117.1 - 0.07 12.8 0.0 0.38 10.4 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain UPF0079 PF02367.12 KKK25117.1 - 0.085 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 KKK25117.1 - 0.098 12.1 0.0 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.18 KKK25117.1 - 0.13 11.6 0.1 0.39 10.0 0.1 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.15 KKK25117.1 - 0.17 10.5 2.6 1.7 7.2 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit ACBP PF00887.14 KKK25119.1 - 1.5e-27 95.0 0.0 2.7e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Atg14 PF10186.4 KKK25119.1 - 0.011 14.7 0.3 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TraP PF07296.6 KKK25119.1 - 0.13 11.2 2.0 0.24 10.3 1.4 1.3 1 0 0 1 1 1 0 TraP protein Nop14 PF04147.7 KKK25119.1 - 1 7.1 17.4 1.8 6.4 12.0 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KKK25119.1 - 5.1 5.0 13.1 7.4 4.4 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 KKK25119.1 - 8.7 4.3 7.4 13 3.6 5.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 tRNA-synt_2d PF01409.15 KKK25133.1 - 4.9e-48 163.4 0.3 1.4e-25 89.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KKK25133.1 - 2.6e-27 94.8 0.0 6.9e-27 93.4 0.0 1.8 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.14 KKK25134.1 - 2.8e-42 144.0 5.9 4e-42 143.5 4.1 1.2 1 0 0 1 1 1 1 GrpE Focal_AT PF03623.8 KKK25134.1 - 0.05 13.0 0.7 0.082 12.3 0.5 1.4 1 1 0 1 1 1 0 Focal adhesion targeting region Mito_carr PF00153.22 KKK25135.1 - 6e-61 202.1 0.4 6.9e-20 70.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SHS2_Rpb7-N PF03876.12 KKK25136.1 - 2.6e-07 30.6 0.0 5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Mucin PF01456.12 KKK25136.1 - 0.002 17.8 5.7 0.002 17.8 3.9 2.5 2 0 0 2 2 2 1 Mucin-like glycoprotein Dicty_REP PF05086.7 KKK25136.1 - 0.0038 15.0 1.5 0.0038 15.0 1.0 2.0 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein U79_P34 PF03064.11 KKK25136.1 - 0.066 12.7 8.4 5.8 6.3 6.9 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF702 PF05142.7 KKK25136.1 - 0.28 11.3 6.9 6.4 6.9 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Menin PF05053.8 KKK25136.1 - 0.5 8.4 13.5 0.18 9.9 1.5 2.1 2 0 0 2 2 2 0 Menin DUF3439 PF11921.3 KKK25136.1 - 0.61 9.8 14.0 0.21 11.3 5.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4544 PF15077.1 KKK25136.1 - 5.1 6.5 7.8 2.1 7.7 3.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) AJAP1_PANP_C PF15298.1 KKK25136.1 - 6.2 6.6 15.8 0.17 11.7 5.1 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus RNA_polI_A34 PF08208.6 KKK25136.1 - 7 6.2 30.6 0.38 10.3 15.2 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Arrestin_N PF00339.24 KKK25137.1 - 5.4e-15 55.5 0.5 1.6e-10 40.9 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 KKK25137.1 - 0.014 14.5 0.2 0.025 13.6 0.1 1.5 1 0 0 1 1 1 0 Rgp1 Bul1_C PF04426.7 KKK25137.1 - 0.063 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Bul1 C terminus F-box-like PF12937.2 KKK25138.1 - 0.005 16.5 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like V-ATPase_G PF03179.10 KKK25139.1 - 5.6e-30 103.7 16.5 6.6e-30 103.5 11.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KKK25139.1 - 0.017 14.9 10.8 0.017 14.9 7.5 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF29 PF01724.11 KKK25139.1 - 0.1 12.4 4.1 0.14 11.9 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF29 Colicin-DNase PF12639.2 KKK25139.1 - 0.16 12.2 7.1 0.25 11.6 4.9 1.5 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Clathrin_lg_ch PF01086.12 KKK25139.1 - 0.28 11.0 13.7 0.29 11.0 9.5 1.0 1 0 0 1 1 1 0 Clathrin light chain S_layer_C PF05124.7 KKK25139.1 - 0.29 10.7 4.0 0.34 10.4 2.8 1.0 1 0 0 1 1 1 0 S-layer like family, C-terminal region CAF-1_p150 PF11600.3 KKK25139.1 - 0.33 10.3 22.2 0.36 10.1 15.4 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3552 PF12072.3 KKK25139.1 - 0.42 9.7 20.2 0.044 12.9 9.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) HypD PF01924.11 KKK25139.1 - 0.54 8.9 2.1 0.63 8.7 1.4 1.0 1 0 0 1 1 1 0 Hydrogenase formation hypA family ECM11 PF15463.1 KKK25139.1 - 0.63 10.3 10.6 0.92 9.7 7.4 1.3 1 1 0 1 1 1 0 Extracellular mutant protein 11 DUF2870 PF11069.3 KKK25139.1 - 0.81 9.7 7.1 1.1 9.3 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DUF3154 PF11351.3 KKK25139.1 - 1 9.1 3.2 1.3 8.7 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3154) Nucleoporin2 PF04096.9 KKK25139.1 - 1.5 8.6 5.1 9 6.1 2.0 2.1 1 1 1 2 2 2 0 Nucleoporin autopeptidase DUF2151 PF10221.4 KKK25139.1 - 1.6 6.7 8.0 1.9 6.5 5.6 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DNA_primase_lrg PF04104.9 KKK25139.1 - 1.8 7.7 5.6 2.1 7.5 3.9 1.0 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DUF4604 PF15377.1 KKK25139.1 - 2.2 8.4 16.0 2.8 8.1 11.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RRF PF01765.14 KKK25139.1 - 2.5 7.5 14.1 3.2 7.2 9.7 1.1 1 0 0 1 1 1 0 Ribosome recycling factor KfrA_N PF11740.3 KKK25139.1 - 2.6 8.4 10.2 0.28 11.6 3.2 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Muted PF14942.1 KKK25139.1 - 3 7.7 11.5 2 8.3 7.0 1.4 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein AIF-MLS PF14962.1 KKK25139.1 - 3.3 7.3 10.2 3.9 7.0 7.1 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence HrpE PF06188.7 KKK25139.1 - 4.8 6.8 8.6 10 5.8 5.8 1.6 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF883 PF05957.8 KKK25139.1 - 6.5 7.2 9.0 22 5.5 6.2 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) U79_P34 PF03064.11 KKK25139.1 - 6.7 6.1 10.7 7.2 6.0 7.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pyr_redox_2 PF07992.9 KKK25141.1 - 8.3e-27 94.3 0.1 2.3e-26 92.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KKK25141.1 - 1.7e-14 53.1 0.1 4.3e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 KKK25141.1 - 8.4e-10 38.9 0.2 3.4e-08 33.7 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KKK25141.1 - 3.3e-05 23.5 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.1 KKK25141.1 - 9.8e-05 22.5 0.1 0.00057 20.1 0.0 2.3 2 0 0 2 2 2 1 Reductase C-terminal DUF1188 PF06690.6 KKK25141.1 - 0.035 13.2 0.2 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.1 KKK25141.1 - 0.059 13.1 1.3 9 6.0 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Zn_clus PF00172.13 KKK25142.1 - 0.00027 20.8 2.8 0.00027 20.8 2.0 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK25142.1 - 0.002 16.7 0.0 0.0031 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nucleopor_Nup85 PF07575.8 KKK25143.1 - 7e-18 64.1 0.0 1.1e-08 33.7 0.0 2.9 2 1 0 2 2 2 2 Nup85 Nucleoporin DUF106 PF01956.11 KKK25144.1 - 0.055 13.0 0.3 0.064 12.7 0.2 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF3824 PF12868.2 KKK25144.1 - 0.081 13.8 0.1 0.11 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) IDO PF01231.13 KKK25145.1 - 3.8e-39 134.3 0.0 5.8e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPR_11 PF13414.1 KKK25146.1 - 5.3e-12 45.2 2.9 6.4e-09 35.3 0.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KKK25146.1 - 1.5e-07 30.7 4.1 0.046 13.6 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat LRR_8 PF13855.1 KKK25146.1 - 6.6e-07 28.9 4.2 0.029 14.1 0.2 4.8 3 3 1 4 4 4 2 Leucine rich repeat F-box PF00646.28 KKK25146.1 - 2.7e-06 26.9 0.2 8.5e-06 25.2 0.2 1.9 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.23 KKK25146.1 - 4.1e-06 26.1 3.0 0.71 9.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK25146.1 - 6.1e-06 26.7 1.4 0.003 18.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KKK25146.1 - 0.0012 18.9 1.5 0.32 11.1 0.3 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KKK25146.1 - 0.0014 18.5 4.9 0.03 14.2 0.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 KKK25146.1 - 0.0017 18.6 1.1 0.013 15.7 0.8 2.0 1 1 0 1 1 1 1 Bacterial transcriptional activator domain TPR_19 PF14559.1 KKK25146.1 - 0.0026 18.0 2.7 0.014 15.7 0.6 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK25146.1 - 0.0035 17.8 3.3 2.9 8.7 0.3 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat F-box-like PF12937.2 KKK25146.1 - 0.0044 16.7 0.2 0.0085 15.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like NARP1 PF12569.3 KKK25146.1 - 0.013 14.3 1.9 0.017 13.8 1.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 KKK25146.1 - 0.032 14.0 1.4 14 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PRANC PF09372.5 KKK25146.1 - 0.035 14.0 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 PRANC domain LRR_7 PF13504.1 KKK25146.1 - 0.049 13.8 4.4 24 5.7 0.0 6.2 7 0 0 7 7 5 0 Leucine rich repeat TPR_9 PF13371.1 KKK25146.1 - 0.095 12.5 1.4 14 5.5 0.2 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF742 PF05331.6 KKK25146.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) TPR_15 PF13429.1 KKK25146.1 - 0.16 11.0 4.0 30 3.5 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat LRR_6 PF13516.1 KKK25146.1 - 0.18 11.9 12.4 41 4.6 0.0 7.3 8 0 0 8 8 8 0 Leucine Rich repeat TPR_6 PF13174.1 KKK25146.1 - 3.3 8.3 5.5 4.4 7.9 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat ADIP PF11559.3 KKK25147.1 - 6.3e-44 149.5 6.9 6.3e-44 149.5 4.8 3.1 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 KKK25147.1 - 0.0018 17.8 7.9 0.2 11.1 4.9 2.6 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 KKK25147.1 - 0.0041 15.6 1.9 0.009 14.5 1.3 1.6 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.6 KKK25147.1 - 0.02 13.5 6.3 0.047 12.3 4.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.6 KKK25147.1 - 0.41 10.5 2.6 1.7 8.5 0.2 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) adh_short PF00106.20 KKK25148.1 - 3.4e-22 79.1 0.1 5.1e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK25148.1 - 4.4e-16 59.3 0.0 5.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 KKK25148.1 - 0.00053 19.5 0.1 0.0092 15.5 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1776 PF08643.5 KKK25148.1 - 0.00063 18.9 0.0 0.002 17.3 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GARS_C PF02843.11 KKK25148.1 - 0.0014 18.7 0.0 0.0046 17.0 0.0 1.8 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain NmrA PF05368.8 KKK25148.1 - 0.0065 15.7 0.1 0.032 13.4 0.0 2.0 3 0 0 3 3 3 1 NmrA-like family Epimerase PF01370.16 KKK25148.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK25148.1 - 0.025 14.5 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 KKK25148.1 - 0.044 12.9 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KKK25148.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F-box-like PF12937.2 KKK25149.1 - 9e-07 28.5 0.6 2e-06 27.4 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK25149.1 - 9.1e-07 28.3 1.2 9.1e-07 28.3 0.8 2.1 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 KKK25149.1 - 0.075 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 PRANC domain HSF_DNA-bind PF00447.12 KKK25150.1 - 7.6e-36 122.4 0.6 1.2e-35 121.7 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ribosomal_L13e PF01294.13 KKK25152.1 - 2.2e-43 147.8 2.5 6.6e-43 146.2 1.7 1.8 1 0 0 1 1 1 1 Ribosomal protein L13e IncA PF04156.9 KKK25152.1 - 1.5 8.3 7.0 3.1 7.3 4.8 1.5 1 0 0 1 1 1 0 IncA protein DUF3245 PF11595.3 KKK25153.1 - 4.8e-52 176.2 8.2 4.8e-52 176.2 5.7 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) Myc_N PF01056.13 KKK25153.1 - 0.088 11.9 3.7 0.089 11.9 1.2 1.9 2 0 0 2 2 2 0 Myc amino-terminal region CDC45 PF02724.9 KKK25153.1 - 6.5 4.6 8.3 8.6 4.2 5.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Oxidored-like PF09791.4 KKK25154.1 - 3.5e-25 87.1 3.4 7.5e-25 86.1 2.3 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal LRR_4 PF12799.2 KKK25155.1 - 3.3e-35 119.1 38.0 4e-11 42.2 1.2 9.7 7 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK25155.1 - 2.3e-25 88.0 33.5 2.1e-07 30.5 0.5 8.0 6 2 3 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 KKK25155.1 - 4.1e-17 59.5 39.7 0.063 13.3 0.2 14.1 14 2 0 14 14 14 6 Leucine Rich Repeat LRR_7 PF13504.1 KKK25155.1 - 3.7e-15 53.3 35.6 0.31 11.3 0.1 14.0 15 0 0 15 15 15 5 Leucine rich repeat LRR_6 PF13516.1 KKK25155.1 - 2.8e-10 39.1 26.0 1.1 9.4 0.0 11.4 13 0 0 13 13 13 5 Leucine Rich repeat LRR_9 PF14580.1 KKK25155.1 - 0.27 10.7 8.5 2.3 7.7 0.9 3.3 2 2 2 4 4 4 0 Leucine-rich repeat GCIP PF13324.1 KKK25156.1 - 1.2e-11 44.3 0.9 1.7e-11 43.9 0.7 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Nop14 PF04147.7 KKK25156.1 - 0.0084 14.1 7.5 0.01 13.8 5.2 1.1 1 0 0 1 1 1 1 Nop14-like family Sigma70_ner PF04546.8 KKK25156.1 - 0.01 15.4 5.3 0.016 14.8 3.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 KKK25156.1 - 0.013 13.5 2.8 0.015 13.4 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 KKK25156.1 - 0.078 12.5 8.1 0.11 12.1 5.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Vfa1 PF08432.5 KKK25156.1 - 0.089 12.8 3.9 0.14 12.1 2.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_RNA_Pol_19 PF05320.7 KKK25156.1 - 0.24 11.1 3.9 0.36 10.5 2.7 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TRAP_alpha PF03896.11 KKK25156.1 - 0.45 9.4 4.4 0.59 9.0 3.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.6 KKK25156.1 - 0.68 7.9 3.5 0.8 7.7 2.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2890 PF11081.3 KKK25156.1 - 2.4 8.1 11.3 4.2 7.3 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Myc_N PF01056.13 KKK25156.1 - 8.1 5.5 7.3 12 4.8 5.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region ATP-grasp_2 PF08442.5 KKK25157.1 - 1.5e-77 259.5 0.3 1.5e-77 259.5 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KKK25157.1 - 3.4e-25 88.4 0.3 3.4e-25 88.4 0.2 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 KKK25157.1 - 1.8e-08 33.8 0.3 4.6e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KKK25157.1 - 0.00011 21.8 1.6 0.005 16.4 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peripla_BP_2 PF01497.13 KKK25157.1 - 0.0045 16.1 0.2 0.0098 15.0 0.2 1.5 1 0 0 1 1 1 1 Periplasmic binding protein Succ_CoA_lig PF13607.1 KKK25157.1 - 0.0097 15.5 0.3 7.5 6.1 0.0 3.2 2 1 1 3 3 3 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 KKK25157.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Gryzun PF07919.7 KKK25158.1 - 9.9e-145 482.9 2.5 1.4e-144 482.4 0.3 1.9 2 0 0 2 2 2 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KKK25158.1 - 9.4e-100 333.1 1.2 3.3e-91 305.1 0.8 2.6 3 0 0 3 3 3 2 Foie gras liver health family 1 TPR_19 PF14559.1 KKK25158.1 - 0.099 12.9 0.1 23 5.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Gryzun-like PF12742.2 KKK25158.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.2 KKK25159.1 - 7.1e-19 68.5 0.3 3.1e-18 66.4 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK25159.1 - 1.3e-09 37.9 0.1 0.00043 20.0 0.0 2.6 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK25159.1 - 4e-07 29.8 0.0 7.7e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PEMT PF04191.8 KKK25160.1 - 9.5e-33 112.4 1.6 2.1e-32 111.3 1.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase YrhK PF14145.1 KKK25160.1 - 0.063 12.9 0.7 0.063 12.9 0.5 2.1 3 0 0 3 3 3 0 YrhK-like protein DUF1223 PF06764.6 KKK25160.1 - 0.15 11.8 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) RXT2_N PF08595.6 KKK25161.1 - 2.7e-42 144.0 0.1 2.7e-42 144.0 0.1 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal Sigma70_ner PF04546.8 KKK25161.1 - 0.91 9.1 10.2 3 7.4 0.2 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Thioredoxin PF00085.15 KKK25162.1 - 7e-23 80.2 0.2 7.2e-17 60.9 0.3 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KKK25162.1 - 1.3e-07 31.8 0.2 1.7e-06 28.2 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KKK25162.1 - 6.9e-06 26.0 0.0 0.00039 20.4 0.0 2.9 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 KKK25162.1 - 0.0099 15.5 0.1 0.031 13.9 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_3 PF13192.1 KKK25162.1 - 0.028 14.2 0.0 4.7 7.1 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_6 PF13848.1 KKK25162.1 - 0.036 13.8 0.0 0.28 10.9 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KKK25162.1 - 0.081 12.9 0.0 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like SR-25 PF10500.4 KKK25162.1 - 5.3 6.4 10.2 8.9 5.7 7.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein F-box PF00646.28 KKK25163.1 - 1.2e-07 31.1 0.1 4.6e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KKK25163.1 - 3.9e-07 29.6 1.7 5e-07 29.3 0.2 2.0 2 0 0 2 2 2 1 F-box-like Sugar_tr PF00083.19 KKK25164.1 - 5.2e-101 338.4 16.0 8.6e-101 337.7 10.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25164.1 - 1e-20 73.8 36.8 1.8e-13 49.9 11.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3723 PF12520.3 KKK25165.1 - 0.0017 16.9 2.2 0.0024 16.4 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) GNAT_acetyltr_2 PF13718.1 KKK25166.1 - 9.7e-79 263.2 0.0 1.6e-78 262.5 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KKK25166.1 - 1.6e-66 223.2 0.0 4.4e-66 221.8 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KKK25166.1 - 3.6e-40 135.5 0.0 9.5e-40 134.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KKK25166.1 - 1.7e-36 124.3 0.5 5.3e-36 122.7 0.3 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_19 PF13245.1 KKK25166.1 - 0.048 13.4 0.3 0.45 10.2 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Acetyltransf_1 PF00583.19 KKK25166.1 - 0.06 13.3 0.0 0.38 10.8 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK25166.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATP-synt PF00231.14 KKK25167.1 - 3.6e-57 193.9 3.4 6.5e-57 193.0 2.4 1.4 1 1 0 1 1 1 1 ATP synthase Glyco_trans_1_4 PF13692.1 KKK25167.1 - 0.048 13.8 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Topoisom_I_N PF02919.10 KKK25168.1 - 2.3e-95 317.9 1.5 2.3e-95 317.9 1.1 3.5 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KKK25168.1 - 1.1e-82 276.7 8.6 1.1e-82 276.7 6.0 2.1 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KKK25168.1 - 4.1e-33 112.8 0.5 1.2e-32 111.3 0.3 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KKK25168.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.7 1 0 0 1 1 1 0 RolB/RolC glucosidase family Pkinase PF00069.20 KKK25171.1 - 4.6e-56 189.8 0.0 6.2e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK25171.1 - 2.8e-41 141.3 0.0 4.2e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK25171.1 - 7e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK25171.1 - 0.00066 19.4 0.0 0.0021 17.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK25171.1 - 0.0047 16.0 0.3 0.015 14.4 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KKK25171.1 - 0.35 10.2 2.1 0.86 8.9 0.2 2.3 2 1 0 2 2 2 0 RIO1 family Pet191_N PF10203.4 KKK25172.1 - 1.9e-28 98.2 3.5 2.4e-28 97.9 2.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KKK25172.1 - 0.23 11.2 2.5 3.3 7.5 0.2 2.4 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Glyco_hydro_75 PF07335.6 KKK25173.1 - 1.3e-36 125.8 0.0 1.7e-22 80.0 0.0 2.3 2 0 0 2 2 2 2 Fungal chitosanase of glycosyl hydrolase group 75 Abhydro_lipase PF04083.11 KKK25174.1 - 1.3e-22 78.9 0.1 4.5e-22 77.1 0.0 1.9 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KKK25174.1 - 5.6e-20 71.8 0.0 8.6e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK25174.1 - 3.7e-07 30.2 0.0 5.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK25174.1 - 3.2e-05 23.7 0.0 0.00023 20.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KKK25174.1 - 0.018 14.5 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KKK25174.1 - 0.099 12.0 0.0 6.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ras PF00071.17 KKK25175.1 - 7.4e-31 106.7 1.9 7.5e-28 96.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KKK25175.1 - 6.3e-12 46.0 2.2 6.9e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 KKK25175.1 - 0.00023 20.4 0.1 0.0046 16.2 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK25175.1 - 0.0051 16.2 0.0 0.043 13.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KKK25175.1 - 0.18 11.9 2.5 0.79 9.8 0.9 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KKK25175.1 - 3.1 7.7 4.9 12 5.8 0.9 2.5 2 2 0 2 2 2 0 AAA ATPase domain DDOST_48kD PF03345.9 KKK25176.1 - 6.3e-157 522.4 0.0 1.1e-156 521.6 0.0 1.4 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta AAA_11 PF13086.1 KKK25180.1 - 3.3e-62 210.1 0.6 6.8e-62 209.1 0.2 1.7 2 0 0 2 2 1 1 AAA domain AAA_12 PF13087.1 KKK25180.1 - 1.5e-57 194.2 0.0 2.6e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KKK25180.1 - 9.3e-13 48.1 0.0 5.8e-11 42.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK25180.1 - 1.5e-12 47.0 0.1 5.5e-12 45.2 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KKK25180.1 - 2.4e-07 30.5 0.0 0.047 13.1 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KKK25180.1 - 2.4e-07 30.7 0.0 4.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KKK25180.1 - 4.4e-06 25.9 0.1 2.3e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KKK25180.1 - 8.5e-05 22.1 0.1 0.00096 18.6 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.9 KKK25180.1 - 8.8e-05 22.2 0.0 0.17 11.4 0.0 2.9 2 1 0 3 3 3 2 Helicase AAA_22 PF13401.1 KKK25180.1 - 0.00023 21.3 0.1 0.016 15.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KKK25180.1 - 0.00034 20.0 0.2 0.0026 17.1 0.2 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 KKK25180.1 - 0.00043 19.5 0.0 0.012 14.8 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein UvrD_C PF13361.1 KKK25180.1 - 0.00069 19.1 0.0 0.69 9.3 0.0 2.9 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain Flavi_DEAD PF07652.9 KKK25180.1 - 0.0017 18.1 0.1 0.012 15.3 0.1 2.3 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SE PF00437.15 KKK25180.1 - 0.0018 17.2 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 KKK25180.1 - 0.0032 16.9 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein CbiA PF01656.18 KKK25180.1 - 0.0035 16.7 0.1 0.019 14.3 0.1 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 KKK25180.1 - 0.0063 16.5 0.9 0.016 15.2 0.1 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA PF00004.24 KKK25180.1 - 0.0068 16.6 0.0 0.036 14.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KKK25180.1 - 0.0082 15.5 0.0 0.041 13.2 0.0 2.1 1 1 0 2 2 2 1 AAA domain Zot PF05707.7 KKK25180.1 - 0.0095 15.4 0.0 0.025 14.0 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) 4HB_MCP_1 PF12729.2 KKK25180.1 - 0.016 14.5 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction UvrD_C_2 PF13538.1 KKK25180.1 - 0.021 14.9 0.1 4.3 7.5 0.0 3.0 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.4 KKK25180.1 - 0.027 13.1 0.0 0.052 12.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 KKK25180.1 - 0.039 13.3 0.0 1.4 8.2 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_5 PF07728.9 KKK25180.1 - 0.039 13.6 0.1 0.59 9.8 0.0 2.7 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KKK25180.1 - 0.086 13.6 0.6 0.38 11.5 0.4 2.3 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 KKK25180.1 - 0.11 11.4 0.0 3.9 6.3 0.0 2.4 2 1 0 2 2 2 0 PIF1-like helicase Allexi_40kDa PF05549.6 KKK25181.1 - 0.0024 17.2 6.0 0.043 13.0 0.7 2.4 2 0 0 2 2 2 2 Allexivirus 40kDa protein Surfac_D-trimer PF09006.6 KKK25181.1 - 0.042 13.5 1.6 2.3 7.9 0.2 2.8 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation PIG-F PF06699.6 KKK25182.1 - 4.9e-53 179.9 0.1 9.6e-53 178.9 0.0 1.4 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F RhoGAP PF00620.22 KKK25183.1 - 1.3e-38 131.9 0.0 2.1e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Arf PF00025.16 KKK25184.1 - 2.3e-71 238.6 0.2 2.6e-71 238.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KKK25184.1 - 3.7e-13 49.1 0.0 4.1e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KKK25184.1 - 9.4e-13 47.6 1.6 1.9e-09 36.7 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KKK25184.1 - 2.7e-10 39.7 0.0 3.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KKK25184.1 - 1.1e-09 37.7 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK25184.1 - 1.6e-06 28.5 0.0 2.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK25184.1 - 0.00015 21.6 0.1 0.00023 21.1 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK25184.1 - 0.0013 18.1 0.1 0.0026 17.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 KKK25184.1 - 0.014 14.4 0.2 0.031 13.3 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase FeoB_N PF02421.13 KKK25184.1 - 0.022 14.0 0.8 0.034 13.4 0.5 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Glycos_transf_1 PF00534.15 KKK25185.1 - 2.2e-15 56.4 0.0 8.6e-15 54.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KKK25185.1 - 4.7e-09 36.5 0.0 2.4e-08 34.2 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KKK25185.1 - 4e-05 23.8 0.0 8.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3646 PF12362.3 KKK25185.1 - 0.0088 15.9 0.0 0.026 14.4 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III gamma and tau subunits C terminal MIP PF00230.15 KKK25186.1 - 8.2e-33 113.7 3.8 1.2e-32 113.2 2.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein Fungal_trans_2 PF11951.3 KKK25186.1 - 6.6e-20 71.0 3.6 1.2e-19 70.2 2.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25186.1 - 6.5e-08 32.3 8.9 1.3e-07 31.4 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_3_Rpc31 PF11705.3 KKK25187.1 - 0.62 9.9 6.9 1.2 9.0 4.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BSP_II PF05432.6 KKK25187.1 - 1.2 8.3 14.4 2.3 7.4 10.0 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) VID27 PF08553.5 KKK25187.1 - 2.1 6.4 5.6 3.1 5.8 3.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Myc_N PF01056.13 KKK25187.1 - 6.5 5.8 9.4 14 4.7 6.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF726 PF05277.7 KKK25222.1 - 4.5e-129 430.2 1.6 6.1e-129 429.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 KKK25222.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) Menin PF05053.8 KKK25222.1 - 2.6 6.1 6.2 5.5 5.0 4.3 1.4 1 0 0 1 1 1 0 Menin RTC4 PF14474.1 KKK25223.1 - 9.5e-38 128.9 0.0 1.9e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain zf-MIZ PF02891.15 KKK25223.1 - 0.15 11.6 1.1 0.26 10.8 0.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger adh_short PF00106.20 KKK25230.1 - 2.4e-13 50.3 0.1 2.8e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK25230.1 - 3.1e-12 46.5 0.0 3.6e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK25230.1 - 0.023 14.4 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KNTase_C PF07827.6 KKK25230.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 KNTase C-terminal domain TPR_11 PF13414.1 KKK25251.1 - 6.1e-06 25.8 7.9 0.043 13.4 0.1 4.8 4 1 0 4 4 4 3 TPR repeat TPR_17 PF13431.1 KKK25251.1 - 0.0061 16.6 0.4 2.3 8.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK25251.1 - 0.16 12.6 16.6 0.53 11.0 0.2 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KKK25251.1 - 0.4 10.6 9.6 1.5 8.8 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Nnf1 PF03980.9 KKK25252.1 - 2.6e-32 111.0 0.8 4.5e-32 110.2 0.6 1.4 1 0 0 1 1 1 1 Nnf1 Spc42p PF11544.3 KKK25252.1 - 0.057 13.3 1.2 0.2 11.6 0.0 2.3 2 1 1 3 3 3 0 Spindle pole body component Spc42p CR6_interact PF10147.4 KKK25252.1 - 0.15 11.4 3.4 0.22 10.8 0.7 2.0 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1348 PF07080.6 KKK25286.1 - 1.5e-44 151.2 2.7 2.1e-44 150.8 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.1 KKK25286.1 - 5.6e-06 26.5 0.1 7.9e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KKK25286.1 - 1.3e-05 25.5 0.3 4.4e-05 23.8 0.2 1.8 1 1 0 1 1 1 1 SnoaL-like domain Zn_clus PF00172.13 KKK25287.1 - 5e-09 35.9 7.4 7e-09 35.4 5.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KKK25288.1 - 4.4e-69 232.5 0.0 6.8e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK25288.1 - 3.2e-35 121.4 0.0 1.5e-33 115.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK25288.1 - 8.6e-06 25.6 0.1 0.0026 17.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KKK25288.1 - 0.00015 20.9 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KKK25288.1 - 0.0094 15.5 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KKK25288.1 - 0.014 14.3 0.0 0.032 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Redoxin PF08534.5 KKK25289.1 - 1.5e-35 121.8 0.0 1.7e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KKK25289.1 - 1.3e-15 57.1 0.0 1.8e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF1690 PF07956.6 KKK25290.1 - 2.4e-28 98.9 5.9 1.2e-14 54.4 0.4 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Apolipoprotein PF01442.13 KKK25290.1 - 0.011 15.2 5.2 0.62 9.5 0.8 2.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Plasmid_RAQPRD PF09686.5 KKK25290.1 - 0.012 15.6 0.1 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) cwf21 PF08312.7 KKK25290.1 - 0.016 15.0 3.7 0.76 9.6 1.2 2.4 2 0 0 2 2 2 0 cwf21 domain IFT57 PF10498.4 KKK25290.1 - 0.078 11.7 1.6 0.83 8.3 0.2 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF848 PF05852.6 KKK25290.1 - 0.12 12.1 2.7 0.29 10.9 0.2 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Phasin PF05597.6 KKK25290.1 - 0.21 11.3 4.4 0.18 11.5 0.4 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Matrilin_ccoil PF10393.4 KKK25290.1 - 0.95 8.8 5.7 11 5.4 1.1 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin POP1 PF06978.6 KKK25291.1 - 6.2e-67 224.8 13.2 6.2e-67 224.8 9.2 2.2 3 0 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KKK25291.1 - 1.1e-32 111.6 1.2 1.1e-32 111.6 0.9 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain YTH PF04146.10 KKK25292.1 - 3.2e-56 188.7 0.0 5.2e-56 188.1 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 KKK25292.1 - 8e-07 28.6 0.0 1.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK25292.1 - 1.1e-05 25.2 0.0 2.8e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK25292.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleoplasmin PF03066.10 KKK25292.1 - 0.21 11.1 2.9 0.34 10.3 2.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin Aminotran_1_2 PF00155.16 KKK25294.1 - 1.3e-49 169.1 0.0 1.8e-32 112.7 0.0 2.1 1 1 0 2 2 2 2 Aminotransferase class I and II Aminotran_5 PF00266.14 KKK25294.1 - 0.0085 14.8 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KKK25294.1 - 0.19 10.8 0.0 0.79 8.8 0.0 1.8 2 0 0 2 2 2 0 Beta-eliminating lyase AMP-binding PF00501.23 KKK25295.1 - 7e-42 143.2 0.0 9.4e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK25295.1 - 3.2e-05 24.8 0.0 0.00013 22.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4211 PF13926.1 KKK25296.1 - 4.3e-36 123.6 0.0 1e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Toxin_14 PF07829.6 KKK25296.1 - 0.31 10.7 5.1 0.65 9.7 3.5 1.5 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein HLH PF00010.21 KKK25298.1 - 2.2e-14 52.8 0.5 5.3e-14 51.6 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sugar_tr PF00083.19 KKK25299.1 - 2.8e-96 322.8 24.4 3.2e-96 322.6 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25299.1 - 9.2e-30 103.5 30.1 9.7e-22 77.1 3.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK25299.1 - 0.0072 14.7 29.0 0.0078 14.6 4.5 3.7 3 1 1 4 4 4 2 MFS/sugar transport protein IU_nuc_hydro PF01156.14 KKK25300.1 - 9.4e-11 41.4 0.2 1e-09 38.0 0.1 1.9 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Halo_GVPC PF05465.8 KKK25300.1 - 2.3 8.2 5.1 3.9 7.4 3.5 1.3 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Pyr_redox_3 PF13738.1 KKK25301.1 - 8.2e-15 55.3 0.0 1.7e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK25301.1 - 6.1e-13 47.8 0.0 1.8e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KKK25301.1 - 2e-07 30.8 0.3 0.00016 21.5 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK25301.1 - 2.9e-07 30.5 0.0 1.3e-06 28.4 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK25301.1 - 1e-06 28.6 0.2 3e-05 23.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KKK25301.1 - 7.9e-06 25.0 0.0 0.0022 16.9 0.0 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KKK25301.1 - 0.00052 20.3 0.0 0.6 10.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KKK25301.1 - 0.057 12.4 0.5 0.42 9.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK25301.1 - 0.23 10.5 0.0 0.23 10.5 0.0 2.1 3 0 0 3 3 3 0 Thi4 family HI0933_like PF03486.9 KKK25301.1 - 0.3 9.5 0.0 0.44 8.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Tom22 PF04281.8 KKK25302.1 - 1.8e-53 179.7 1.3 2e-53 179.5 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Peptidase_M16_C PF05193.16 KKK25303.1 - 1.8e-52 177.6 0.0 2.1e-51 174.2 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KKK25303.1 - 4.1e-42 143.4 0.0 1.1e-40 138.8 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Nup160 PF11715.3 KKK25304.1 - 5.1e-172 572.8 2.4 7.6e-172 572.2 1.6 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_12 PF13424.1 KKK25304.1 - 3 7.8 8.4 8.8 6.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.22 KKK25305.1 - 5e-41 140.2 0.0 7.4e-19 68.4 0.0 3.6 3 0 0 3 3 3 3 ABC transporter ABC_membrane PF00664.18 KKK25305.1 - 3.3e-25 89.0 23.9 2.3e-21 76.4 4.4 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KKK25305.1 - 9.2e-09 34.8 0.3 0.0012 18.1 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KKK25305.1 - 7.6e-07 29.2 0.2 0.00098 19.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KKK25305.1 - 1.3e-06 28.6 0.2 0.058 13.3 0.0 3.3 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 KKK25305.1 - 0.00018 20.7 0.1 0.0007 18.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 KKK25305.1 - 0.00034 20.8 0.3 0.023 14.8 0.0 3.7 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KKK25305.1 - 0.00084 18.8 0.1 0.0026 17.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KKK25305.1 - 0.0034 17.2 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KKK25305.1 - 0.0037 17.1 0.3 3.4 7.6 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KKK25305.1 - 0.0049 16.9 0.6 0.18 11.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KKK25305.1 - 0.0063 16.6 0.1 0.2 11.8 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Miro PF08477.8 KKK25305.1 - 0.014 15.8 0.0 4.1 7.9 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_25 PF13481.1 KKK25305.1 - 0.014 14.7 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KKK25305.1 - 0.015 15.2 0.0 0.073 13.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 KKK25305.1 - 0.021 15.1 0.2 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KKK25305.1 - 0.033 13.0 0.0 0.096 11.5 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 KKK25305.1 - 0.039 13.3 0.2 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 KKK25305.1 - 0.084 12.5 0.2 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KKK25305.1 - 0.17 11.4 0.2 5.7 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KKK25305.1 - 0.2 12.5 0.1 0.73 10.6 0.1 2.0 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 KKK25305.1 - 0.21 10.1 0.5 14 4.1 0.0 2.9 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Rad51 PF08423.6 KKK25306.1 - 3.5e-138 458.6 0.0 4.9e-138 458.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KKK25306.1 - 1.2e-13 50.9 0.0 2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KKK25306.1 - 5.7e-08 32.1 0.0 8.5e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KKK25306.1 - 7e-07 29.3 0.1 1.6e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 KKK25306.1 - 1.5e-05 24.1 0.1 4.1e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.6 KKK25306.1 - 0.051 12.4 0.1 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 PAXNEB protein DnaB_C PF03796.10 KKK25306.1 - 0.053 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AMP-binding PF00501.23 KKK25307.1 - 1.8e-302 1001.6 0.0 1.5e-83 280.5 0.0 5.0 4 1 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KKK25307.1 - 1.1e-236 782.8 0.8 3.2e-52 177.2 0.0 9.1 8 2 0 8 8 8 6 Condensation domain PP-binding PF00550.20 KKK25307.1 - 5.8e-48 161.0 0.0 3.6e-11 43.1 0.0 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK25307.1 - 4.7e-12 46.6 0.0 0.0031 18.4 0.0 4.8 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain AATase PF07247.7 KKK25307.1 - 0.0026 16.3 0.0 4.8 5.6 0.0 3.6 3 0 0 3 3 3 1 Alcohol acetyltransferase HxxPF_rpt PF13745.1 KKK25307.1 - 0.2 11.9 2.2 4.7 7.6 0.0 4.0 5 0 0 5 5 5 0 HxxPF-repeated domain SbcD_C PF12320.3 KKK25307.1 - 0.48 10.4 0.4 43 4.2 0.1 3.5 4 0 0 4 4 4 0 Type 5 capsule protein repressor C-terminal domain MFS_1 PF07690.11 KKK25308.1 - 4.9e-35 120.8 45.4 2.1e-32 112.2 12.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK25308.1 - 3.5e-08 32.4 17.4 3.5e-08 32.4 12.1 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KKK25308.1 - 0.00012 20.4 2.6 0.00012 20.4 1.8 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HLH PF00010.21 KKK25309.1 - 9.9e-07 28.3 1.1 1.9e-06 27.4 0.8 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DIOX_N PF14226.1 KKK25311.1 - 9.4e-23 80.9 0.1 1.4e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK25311.1 - 1.5e-15 57.2 0.0 4.1e-15 55.8 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OrgA_MxiK PF09482.5 KKK25311.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) DUF4037 PF13228.1 KKK25311.1 - 0.13 12.4 0.0 9.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) DUF3433 PF11915.3 KKK25312.1 - 4.4e-43 145.3 10.8 1.9e-23 82.4 2.3 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Wzy_C PF04932.10 KKK25312.1 - 0.018 14.8 0.0 14 5.4 0.0 3.5 3 1 0 3 3 3 0 O-Antigen ligase Glyco_hydro_61 PF03443.9 KKK25313.1 - 7.2e-39 133.8 0.0 9.8e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.20 KKK25314.1 - 4.2e-30 104.8 0.4 5.8e-30 104.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK25314.1 - 3.6e-21 76.0 0.0 5e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK25314.1 - 1.5e-10 41.0 0.1 2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK25314.1 - 5.8e-07 29.6 0.0 8.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KKK25314.1 - 2.6e-05 23.5 0.0 3.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KKK25314.1 - 0.00044 19.7 0.1 0.0011 18.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KKK25314.1 - 0.009 15.2 0.2 0.11 11.7 0.2 2.0 2 0 0 2 2 2 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 KKK25314.1 - 0.02 14.6 0.2 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_2_N PF02837.13 KKK25315.1 - 7.4e-25 87.4 0.0 1.8e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KKK25315.1 - 9.9e-12 44.3 0.0 2.9e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KKK25315.1 - 4.9e-08 33.3 1.6 3.9e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 2 Fungal_trans PF04082.13 KKK25317.1 - 2.2e-12 46.4 0.0 3.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_43 PF04616.9 KKK25318.1 - 1.5e-43 148.9 5.4 1.7e-43 148.7 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ADH_N PF08240.7 KKK25319.1 - 2e-34 117.6 1.1 2e-34 117.6 0.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK25319.1 - 5.4e-23 80.9 0.3 9.4e-23 80.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK25319.1 - 0.0019 19.0 0.1 0.0032 18.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KKK25319.1 - 0.0028 18.2 0.0 0.0049 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KKK25319.1 - 0.02 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 KKK25319.1 - 0.044 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MTS PF05175.9 KKK25319.1 - 0.063 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain 2-Hacid_dh_C PF02826.14 KKK25319.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrmA PF06325.8 KKK25319.1 - 0.15 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AlaDh_PNT_C PF01262.16 KKK25319.1 - 0.24 10.9 2.9 0.13 11.8 0.5 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.27 KKK25320.1 - 0.00028 20.6 11.9 0.0054 16.5 0.0 5.5 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KKK25320.1 - 0.022 14.2 0.9 7.8 5.8 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain FAD-oxidase_C PF02913.14 KKK25321.1 - 2.8e-57 193.9 0.1 4.6e-57 193.1 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KKK25321.1 - 1.3e-35 121.8 0.0 4.4e-35 120.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Het-C PF07217.6 KKK25322.1 - 4.4e-263 874.0 0.0 5.6e-263 873.6 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C RNA_pol_N PF01194.12 KKK25323.1 - 5.4e-11 42.3 1.5 1.3e-10 41.1 1.1 1.6 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit XK-related PF09815.4 KKK25323.1 - 0.0038 16.2 0.2 0.0057 15.6 0.1 1.2 1 0 0 1 1 1 1 XK-related protein Fer4_13 PF13370.1 KKK25323.1 - 0.056 13.8 1.2 10 6.6 0.0 3.8 3 2 1 4 4 4 0 4Fe-4S single cluster domain Clr5 PF14420.1 KKK25324.1 - 1.9e-14 53.2 1.4 6.1e-14 51.6 1.0 2.0 1 0 0 1 1 1 1 Clr5 domain DUF4047 PF13256.1 KKK25324.1 - 0.36 10.7 2.8 14 5.6 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) Dioxygenase_C PF00775.16 KKK25325.1 - 8.5e-39 132.6 0.1 1.4e-38 132.0 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KKK25325.1 - 7.3e-19 67.5 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KKK25325.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Zn_clus PF00172.13 KKK25326.1 - 0.039 13.8 9.7 0.091 12.6 6.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NuA4 PF09340.5 KKK25327.1 - 1.1e-28 98.7 0.6 1.1e-28 98.7 0.4 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Serglycin PF04360.7 KKK25327.1 - 2.5 7.8 15.6 0.42 10.3 0.1 2.6 3 0 0 3 3 3 0 Serglycin Tmemb_cc2 PF10267.4 KKK25327.1 - 3.7 6.0 13.0 1.2 7.6 0.4 1.9 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Ctr PF04145.10 KKK25328.1 - 2.9e-37 127.9 1.4 3.4e-37 127.6 1.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF454 PF04304.8 KKK25328.1 - 0.044 13.8 0.5 0.044 13.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Wzy_C PF04932.10 KKK25328.1 - 0.36 10.6 4.0 12 5.7 0.0 2.1 1 1 1 2 2 2 0 O-Antigen ligase Cupin_8 PF13621.1 KKK25329.1 - 3.3e-16 59.5 0.1 1.4e-14 54.1 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KKK25329.1 - 5.2e-10 39.5 0.3 1e-08 35.3 0.2 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 KKK25329.1 - 3.7e-07 29.7 0.1 7.3e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK25329.1 - 1.9e-05 24.1 0.0 4.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain DEAD PF00270.24 KKK25330.1 - 6e-44 149.5 1.4 8.3e-44 149.0 0.5 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK25330.1 - 8.1e-28 96.1 0.4 2.9e-27 94.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK25330.1 - 0.0024 17.7 0.0 0.0073 16.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KKK25330.1 - 0.0042 17.2 0.2 0.016 15.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 KKK25330.1 - 0.0044 16.1 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 KKK25330.1 - 0.01 15.4 0.0 0.031 13.8 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KKK25330.1 - 0.017 14.8 0.1 0.061 13.0 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain CobA_CobO_BtuR PF02572.10 KKK25330.1 - 0.082 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Fanconi_A PF03511.9 KKK25330.1 - 0.095 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein PWI PF01480.12 KKK25331.1 - 2.9e-29 100.9 0.0 4.9e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 PWI domain FAA_hydrolase PF01557.13 KKK25332.1 - 6.4e-50 169.6 0.0 7.9e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Sugar_tr PF00083.19 KKK25333.1 - 3.3e-42 144.6 17.8 1.2e-41 142.7 12.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25333.1 - 1.1e-17 63.8 35.0 2e-17 62.9 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3533 PF12051.3 KKK25334.1 - 3.6e-109 365.0 17.3 3.7e-64 216.8 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 KKK25334.1 - 9.9e-07 28.1 0.4 9.9e-07 28.1 0.3 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein adh_short PF00106.20 KKK25335.1 - 9.4e-19 67.9 0.1 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK25335.1 - 2.3e-08 34.1 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK25335.1 - 4.1e-08 33.0 0.0 6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK25335.1 - 0.00061 19.8 0.1 0.002 18.1 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KKK25335.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KKK25335.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KKK25335.1 - 0.047 12.5 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WD40 PF00400.27 KKK25336.1 - 6.5e-61 200.1 28.1 5.6e-11 41.8 0.2 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KKK25336.1 - 0.0003 19.0 3.7 0.01 14.0 0.2 3.7 2 2 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KKK25336.1 - 0.053 12.2 1.2 0.65 8.6 0.2 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 KKK25336.1 - 0.091 11.0 0.3 1.5 7.0 0.0 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain Sulfate_tra_GLY PF13792.1 KKK25337.1 - 0.084 12.5 0.2 0.084 12.5 0.2 1.8 2 0 0 2 2 2 0 Sulfate transporter N-terminal domain with GLY motif ABC2_membrane_2 PF12679.2 KKK25337.1 - 3.2 6.5 10.5 1 8.1 0.8 2.3 2 1 0 2 2 2 0 ABC-2 family transporter protein SOG2 PF10428.4 KKK25338.1 - 2e-131 438.7 0.0 3.6e-131 437.9 0.0 1.4 1 0 0 1 1 1 1 RAM signalling pathway protein LRR_4 PF12799.2 KKK25338.1 - 7.8e-15 54.1 5.5 1.4e-08 34.1 2.1 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK25338.1 - 1.8e-12 46.7 4.7 3.4e-07 29.9 0.4 3.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KKK25338.1 - 1.8e-09 36.3 6.7 0.041 13.9 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KKK25338.1 - 6.2e-06 25.5 6.2 1.6 9.3 0.0 5.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KKK25338.1 - 0.011 15.7 4.5 5.5 7.3 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich repeat MRP-S25 PF13741.1 KKK25339.1 - 1.2e-87 293.2 9.9 1.3e-87 293.0 6.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_2 PF13041.1 KKK25340.1 - 1.6e-09 37.5 0.1 0.0078 16.1 0.0 4.5 3 2 2 5 5 5 3 PPR repeat family PPR PF01535.15 KKK25340.1 - 8e-08 31.7 1.0 0.062 13.3 0.0 4.5 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 KKK25340.1 - 1.5e-05 24.8 0.2 2.1 8.8 0.0 5.2 6 0 0 6 6 6 2 Pentatricopeptide repeat domain TPR_14 PF13428.1 KKK25340.1 - 0.034 14.7 0.0 4.5 8.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PaREP1 PF05942.6 KKK25340.1 - 0.059 13.2 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family SET PF00856.23 KKK25341.1 - 6.6e-23 81.7 0.0 1.2e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 SET domain Methyltransf_PK PF05891.7 KKK25342.1 - 6.2e-69 231.6 0.0 7.1e-69 231.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KKK25342.1 - 4.9e-08 32.8 0.0 6.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK25342.1 - 6.4e-06 26.7 0.0 9.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK25342.1 - 0.0001 22.7 0.0 0.00015 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK25342.1 - 0.0021 18.5 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK25342.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LEA_2 PF03168.8 KKK25343.1 - 6.8e-11 42.4 4.1 0.0035 17.6 0.0 4.7 4 1 0 4 4 4 3 Late embryogenesis abundant protein DUF3712 PF12505.3 KKK25343.1 - 2.1e-06 27.7 0.2 8.6e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Helicase_C PF00271.26 KKK25344.1 - 1.1e-17 63.6 0.0 6.5e-14 51.5 0.0 3.7 3 1 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 KKK25344.1 - 4.7e-12 45.7 0.0 1.3e-09 37.7 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase PEHE PF15275.1 KKK25344.1 - 0.32 11.4 0.1 0.32 11.4 0.0 2.6 2 1 0 2 2 2 0 PEHE domain SR-25 PF10500.4 KKK25344.1 - 0.93 8.9 14.3 0.029 13.8 5.4 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein KH_1 PF00013.24 KKK25345.1 - 9.9e-11 41.1 0.0 1e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KKK25345.1 - 2.4e-06 27.0 2.6 0.00019 21.0 0.1 3.1 3 0 0 3 3 3 2 KH domain DUF566 PF04484.7 KKK25345.1 - 4.9 6.5 12.6 18 4.7 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF566) ALS_ss_C PF10369.4 KKK25346.1 - 4.5e-19 67.9 0.0 8.1e-18 63.9 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KKK25346.1 - 8.2e-11 41.1 0.1 1.4e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KKK25346.1 - 2.9e-09 36.6 0.0 5.8e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KKK25346.1 - 0.014 15.0 0.1 3 7.6 0.0 2.7 2 0 0 2 2 2 0 ACT domain Peptidase_S10 PF00450.17 KKK25347.1 - 3.5e-77 260.3 0.0 2.6e-76 257.4 0.0 2.2 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KKK25347.1 - 8.8e-07 29.0 3.0 0.00086 19.2 0.3 2.6 2 2 0 2 2 2 2 Alpha/beta hydrolase family Tcp11 PF05794.8 KKK25348.1 - 1.7e-137 458.7 0.0 2.3e-137 458.3 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 Ydc2-catalyt PF09159.5 KKK25348.1 - 8.4e-82 274.7 0.0 1.3e-81 274.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 KKK25348.1 - 3e-05 23.3 0.0 0.00011 21.6 0.0 2.0 2 0 0 2 2 2 1 SAP domain Pox_A22 PF04848.8 KKK25348.1 - 0.0079 16.0 0.0 3.7 7.3 0.0 3.3 3 0 0 3 3 3 1 Poxvirus A22 protein SelP_N PF04592.9 KKK25349.1 - 0.036 13.4 1.0 0.053 12.8 0.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4587 PF15248.1 KKK25349.1 - 0.19 12.3 1.7 0.46 11.1 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) CTP_transf_2 PF01467.21 KKK25350.1 - 0.00021 21.3 0.0 0.00084 19.4 0.0 1.9 2 1 1 3 3 3 1 Cytidylyltransferase Maff2 PF12750.2 KKK25351.1 - 0.059 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Maff2 family Osmo_CC PF08946.5 KKK25351.1 - 0.069 13.1 1.6 0.11 12.4 1.1 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF533 PF04391.7 KKK25351.1 - 0.19 11.0 1.2 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Fmp27 PF10344.4 KKK25352.1 - 5.3e-248 825.1 0.0 3.5e-247 822.4 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KKK25352.1 - 1.9e-171 570.9 0.7 1.9e-171 570.9 0.5 2.6 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KKK25352.1 - 1.8e-154 514.6 4.3 4.7e-154 513.3 3.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KKK25352.1 - 3.6e-60 202.2 0.3 8.6e-60 201.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 KKK25352.1 - 1.5e-51 174.3 0.0 3.7e-51 173.1 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 KKK25352.1 - 4.6e-33 113.7 0.0 4.3e-32 110.6 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain B-block_TFIIIC PF04182.7 KKK25353.1 - 8.9e-22 76.7 0.2 7.7e-21 73.7 0.0 2.5 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 KKK25353.1 - 0.0052 16.4 2.5 0.035 13.7 0.0 3.1 3 0 0 3 3 3 1 MarR family CGI-121 PF08617.5 KKK25357.1 - 1.5e-55 187.2 0.0 1.7e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF1227 PF06777.6 KKK25357.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1227) Bax1-I PF01027.15 KKK25358.1 - 6.6e-27 94.4 12.6 1e-26 93.7 8.7 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Alpha-amylase PF00128.19 KKK25359.1 - 1.4e-61 208.6 1.0 1.9e-61 208.2 0.7 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KKK25359.1 - 5.6e-30 103.2 0.0 1.1e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) RRM_1 PF00076.17 KKK25360.1 - 2.7e-16 58.9 0.0 3.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK25360.1 - 4.2e-13 49.0 0.0 5.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK25360.1 - 6.4e-11 41.9 0.0 8.8e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.9 KKK25361.1 - 2.8e-21 76.3 4.6 6.1e-15 55.4 0.2 3.2 2 2 0 2 2 2 2 Glycosyl hydrolase family 76 Zn_clus PF00172.13 KKK25363.1 - 0.00015 21.6 7.2 0.00025 20.9 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 KKK25363.1 - 0.0025 17.4 1.4 0.042 13.5 0.1 2.3 1 1 1 2 2 2 2 Homeobox associated leucine zipper DivIC PF04977.10 KKK25363.1 - 0.022 14.2 0.7 0.043 13.3 0.5 1.3 1 0 0 1 1 1 0 Septum formation initiator MbeD_MobD PF04899.7 KKK25363.1 - 0.037 13.9 0.5 0.089 12.7 0.3 1.6 1 0 0 1 1 1 0 MbeD/MobD like ADIP PF11559.3 KKK25363.1 - 0.047 13.5 0.9 0.047 13.5 0.6 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 KKK25363.1 - 0.077 13.3 0.2 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 KKK25363.1 - 0.11 12.7 1.7 0.2 11.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) XRCC4 PF06632.7 KKK25363.1 - 0.38 9.5 15.0 1.2 7.9 0.2 2.2 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Macoilin PF09726.4 KKK25363.1 - 0.55 8.4 9.7 0.77 7.9 6.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4482 PF14818.1 KKK25363.1 - 0.57 10.8 2.9 49 4.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Menin PF05053.8 KKK25363.1 - 8.8 4.3 9.1 16 3.4 6.3 1.4 1 0 0 1 1 1 0 Menin Slx4 PF09494.5 KKK25364.1 - 4e-24 84.1 0.0 7.4e-24 83.2 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease DUF4163 PF13739.1 KKK25364.1 - 0.43 11.3 3.7 8.2 7.2 0.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4163) Tim17 PF02466.14 KKK25365.1 - 0.00016 21.6 1.6 0.00074 19.5 1.2 1.9 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family UCR_Fe-S_N PF10399.4 KKK25365.1 - 0.14 11.3 2.0 0.32 10.2 0.1 2.3 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Dr_adhesin PF12393.3 KKK25365.1 - 0.18 11.9 2.1 0.44 10.7 1.5 1.7 1 0 0 1 1 1 0 Dr family adhesin cNMP_binding PF00027.24 KKK25366.1 - 6.7e-38 128.3 0.0 7.8e-21 73.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 KKK25366.1 - 4.1e-14 51.0 7.4 0.45 10.7 0.1 9.5 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.28 KKK25366.1 - 0.00011 21.7 13.3 13 6.3 0.1 8.9 7 3 2 9 9 9 1 Leucine Rich Repeat F-box-like PF12937.2 KKK25366.1 - 0.00017 21.2 1.8 0.00023 20.7 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK25366.1 - 0.00048 19.7 0.6 0.002 17.7 0.1 2.3 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 KKK25366.1 - 0.00064 19.4 3.4 0.061 13.0 0.2 4.7 6 0 0 6 6 6 1 Leucine rich repeat Cupin_3 PF05899.7 KKK25366.1 - 0.0032 16.8 0.4 0.31 10.4 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Ste50p-SAM PF09235.5 KKK25366.1 - 0.088 12.8 1.5 4.7 7.3 0.2 3.5 3 1 0 3 3 3 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 KKK25366.1 - 0.32 11.3 16.0 52 4.6 0.1 7.8 9 0 0 9 9 9 0 Leucine rich repeat Kinesin PF00225.18 KKK25367.1 - 2.2e-115 384.9 0.0 3.3e-115 384.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 KKK25367.1 - 0.0054 16.5 0.2 0.031 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain PMSR PF01625.16 KKK25370.1 - 4.7e-59 198.7 0.1 5.7e-59 198.4 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Sulfatase PF00884.18 KKK25374.1 - 6.1e-69 232.5 0.0 7.7e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KKK25374.1 - 1.3e-05 24.7 0.0 0.068 12.4 0.0 2.4 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KKK25374.1 - 0.00057 20.1 0.2 0.015 15.5 0.1 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 KKK25374.1 - 0.0024 16.3 0.0 0.0034 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sugar_tr PF00083.19 KKK25375.1 - 1.1e-86 291.1 27.2 1.4e-86 290.8 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25375.1 - 6.6e-17 61.2 15.6 6.6e-17 61.2 10.8 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 KKK25376.1 - 6.5e-10 38.7 8.2 1.3e-09 37.8 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK25376.1 - 1.2e-06 27.6 0.3 3.7e-06 26.0 0.0 1.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain p450 PF00067.17 KKK25377.1 - 9.5e-09 34.2 0.0 1.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2872 PF11071.3 KKK25377.1 - 0.2 11.5 0.5 15 5.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2872) DAO PF01266.19 KKK25378.1 - 7.2e-49 166.5 0.0 1.1e-48 165.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK25378.1 - 7.2e-10 38.2 0.2 1.5e-09 37.2 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KKK25378.1 - 7.6e-06 25.2 0.1 0.00017 20.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK25378.1 - 0.00031 20.7 0.1 0.00086 19.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK25378.1 - 0.00085 18.4 0.2 0.0025 16.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 KKK25378.1 - 0.00098 18.8 0.2 0.0017 18.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KKK25378.1 - 0.0019 18.2 0.2 0.0051 16.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KKK25378.1 - 0.0039 16.1 0.1 0.028 13.2 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KKK25378.1 - 0.005 15.3 0.5 0.0076 14.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KKK25378.1 - 0.011 14.6 0.0 0.035 13.0 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.13 KKK25378.1 - 0.012 13.9 0.0 0.021 13.1 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.22 KKK25378.1 - 0.042 14.2 0.2 0.14 12.5 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 KKK25378.1 - 0.049 13.6 0.2 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding Aa_trans PF01490.13 KKK25379.1 - 3.5e-39 134.4 38.6 4.1e-39 134.2 26.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPRTase PF14681.1 KKK25390.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.5 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase DASH_Dad1 PF08649.5 KKK25391.1 - 1e-22 79.5 2.1 1.4e-22 79.1 1.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 Occludin_ELL PF07303.8 KKK25391.1 - 0.092 13.4 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Occludin homology domain Ras PF00071.17 KKK25392.1 - 1.5e-48 164.2 0.0 1.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK25392.1 - 6.8e-12 45.9 0.0 1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK25392.1 - 5.1e-05 22.5 0.0 0.00017 20.9 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KKK25392.1 - 0.032 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KKK25392.1 - 0.034 13.2 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ERG4_ERG24 PF01222.12 KKK25393.1 - 1.1e-139 465.6 17.8 1.3e-139 465.4 12.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Fungal_trans PF04082.13 KKK25394.1 - 1.2e-20 73.4 0.3 2.6e-20 72.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25394.1 - 1.1e-08 34.8 6.8 2e-08 34.0 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGAP PF00616.14 KKK25395.1 - 1.3e-46 158.7 0.0 2.4e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KKK25395.1 - 2.4e-06 27.3 0.2 1e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 C2 domain APG9 PF04109.11 KKK25396.1 - 1.4e-169 563.8 3.8 1.9e-169 563.4 2.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.15 KKK25397.1 - 4.1e-185 615.7 0.1 5.1e-185 615.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2013 PF09431.5 KKK25398.1 - 2.4e-52 176.4 1.4 5.3e-52 175.2 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) MARVEL PF01284.18 KKK25399.1 - 0.00015 21.5 6.7 0.00027 20.8 4.6 1.4 1 1 0 1 1 1 1 Membrane-associating domain PTS_EIIC PF02378.13 KKK25399.1 - 0.01 14.6 0.7 0.014 14.2 0.5 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF1769 PF08588.5 KKK25399.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) Pyr_redox_3 PF13738.1 KKK25400.1 - 1.1e-29 103.9 0.1 1.9e-29 103.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sulfatase PF00884.18 KKK25400.1 - 1.6e-22 80.0 0.4 3e-22 79.1 0.3 1.4 1 0 0 1 1 1 1 Sulfatase FMO-like PF00743.14 KKK25400.1 - 4.9e-21 74.5 0.4 1.7e-20 72.7 0.1 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK25400.1 - 8e-10 38.1 1.0 9e-08 31.4 0.1 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK25400.1 - 3.7e-09 36.4 0.0 9.6e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK25400.1 - 3e-08 33.7 0.0 8.1e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK25400.1 - 1.9e-06 27.0 0.1 0.00012 21.1 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Phosphodiest PF01663.17 KKK25400.1 - 4e-06 26.4 0.2 7.8e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Shikimate_DH PF01488.15 KKK25400.1 - 8.3e-05 22.7 0.1 0.61 10.1 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KKK25400.1 - 0.00037 20.8 0.9 1.7 9.0 0.4 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK25400.1 - 0.0015 17.6 0.1 0.0041 16.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KKK25400.1 - 0.0016 17.3 0.1 0.0026 16.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KKK25400.1 - 0.0028 17.4 0.7 0.019 14.7 0.0 2.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding DUF229 PF02995.12 KKK25400.1 - 0.0054 15.2 0.0 0.0087 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) NAD_binding_7 PF13241.1 KKK25400.1 - 0.016 15.4 0.0 0.67 10.2 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 KKK25400.1 - 0.19 10.1 2.1 0.17 10.3 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.14 KKK25401.1 - 3.8e-28 98.5 0.0 1.8e-27 96.2 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK25401.1 - 7.5e-26 91.1 0.1 1.6e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK25401.1 - 1.8e-11 43.5 0.0 5e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK25401.1 - 1.7e-07 30.5 0.1 0.0017 17.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK25401.1 - 4.4e-06 26.7 0.0 9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK25401.1 - 6.8e-06 26.0 0.0 2.3e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK25401.1 - 0.00016 20.8 0.1 0.00034 19.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KKK25401.1 - 0.00017 21.7 1.4 0.031 14.3 0.3 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK25401.1 - 0.00045 18.8 0.0 0.00083 17.9 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KKK25401.1 - 0.00059 20.1 0.0 0.43 11.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK25401.1 - 0.00061 18.9 0.0 0.37 9.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK25401.1 - 0.0021 17.2 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KKK25401.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AA_permease PF00324.16 KKK25402.1 - 1.2e-100 337.0 36.7 1.5e-100 336.8 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK25402.1 - 1.2e-31 109.7 40.6 1.4e-31 109.5 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_S28 PF05577.7 KKK25403.1 - 7.2e-46 156.6 0.0 3.1e-45 154.5 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 KKK25403.1 - 0.066 12.4 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ank_4 PF13637.1 KKK25404.1 - 0.0063 17.0 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KKK25404.1 - 0.021 15.1 0.0 0.043 14.1 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK25404.1 - 0.03 14.5 0.0 0.091 13.0 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RasGEF PF00617.14 KKK25405.1 - 5.5e-42 143.6 0.0 9.5e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KKK25405.1 - 1.5e-12 47.5 0.1 3.5e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Transp_cyt_pur PF02133.10 KKK25406.1 - 1.8e-25 89.4 30.6 4.4e-25 88.1 21.2 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 KKK25407.1 - 2.8e-18 65.7 0.0 4.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25407.1 - 1.5e-08 34.4 10.1 2.9e-08 33.4 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc_2 PF13091.1 KKK25408.1 - 1.5e-20 73.1 0.1 7.1e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.3 KKK25408.1 - 0.019 13.9 0.0 0.2 10.6 0.0 2.1 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB PLDc PF00614.17 KKK25408.1 - 0.029 14.1 0.3 0.75 9.6 0.0 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif DUF4322 PF14210.1 KKK25413.1 - 0.06 12.8 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) CBS PF00571.23 KKK25414.1 - 2.8e-40 135.8 8.6 5.2e-10 38.9 0.0 4.7 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KKK25414.1 - 6e-07 29.0 0.2 1.8e-06 27.5 0.0 2.0 2 1 0 2 2 2 1 PB1 domain DUF2408 PF10303.4 KKK25415.1 - 1.2e-53 180.8 1.1 1.5e-31 109.2 0.3 4.9 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.7 KKK25415.1 - 0.04 13.7 1.5 0.1 12.3 0.4 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 KKK25415.1 - 0.18 12.1 4.3 0.46 10.8 0.3 3.2 4 0 0 4 4 4 0 Snapin/Pallidin Prefoldin_2 PF01920.15 KKK25415.1 - 0.37 10.5 3.2 15 5.4 0.0 3.1 3 1 1 4 4 4 0 Prefoldin subunit HEAT_EZ PF13513.1 KKK25416.1 - 8e-20 70.7 19.7 1.3e-08 35.0 0.1 10.4 8 3 3 11 11 11 3 HEAT-like repeat HEAT PF02985.17 KKK25416.1 - 9.3e-20 68.8 11.2 0.00053 19.8 0.0 12.1 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.1 KKK25416.1 - 8e-19 67.7 13.3 9.1e-07 29.0 0.2 8.7 6 2 2 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.2 KKK25416.1 - 8.2e-10 38.9 0.4 0.0086 16.4 0.0 6.4 3 2 3 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KKK25416.1 - 1.7e-06 27.0 0.6 0.00028 19.7 0.1 4.1 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 KKK25416.1 - 2.8e-05 23.5 0.1 0.064 12.6 0.1 5.7 7 1 1 8 8 8 1 CLASP N terminal Cnd1 PF12717.2 KKK25416.1 - 3.8e-05 23.6 0.3 0.82 9.4 0.0 4.8 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.7 KKK25416.1 - 4.4e-05 23.2 0.0 0.019 14.6 0.0 4.2 4 1 0 5 5 4 1 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.4 KKK25416.1 - 0.00049 18.4 1.0 0.0017 16.7 0.1 2.4 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Arm PF00514.18 KKK25416.1 - 0.00053 19.7 8.0 0.065 13.0 0.0 5.4 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 KKK25416.1 - 0.00055 19.9 1.4 4.6 7.1 0.1 5.0 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) IBN_N PF03810.14 KKK25416.1 - 0.0014 18.5 0.2 0.038 13.9 0.0 3.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain TFCD_C PF12612.3 KKK25416.1 - 0.0041 16.5 0.2 2.6 7.4 0.0 3.7 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal Ipi1_N PF12333.3 KKK25416.1 - 0.012 15.6 0.4 6.3 6.8 0.0 4.5 4 1 1 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 KKK25416.1 - 0.038 12.3 6.4 0.015 13.6 0.4 3.0 3 2 0 3 3 3 0 Adaptin N terminal region V-ATPase_H_N PF03224.9 KKK25416.1 - 0.12 11.5 3.6 0.18 10.9 0.1 2.7 3 0 0 3 3 3 0 V-ATPase subunit H Ribosomal_60s PF00428.14 KKK25417.1 - 1.5e-13 50.9 17.2 6.5e-13 48.8 11.9 1.8 1 1 0 1 1 1 1 60s Acidic ribosomal protein DUF3042 PF11240.3 KKK25417.1 - 5.4 6.9 6.2 4.6 7.1 3.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Ribosomal_S26e PF01283.14 KKK25418.1 - 1.7e-51 173.2 6.8 1.9e-51 173.0 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 KKK25418.1 - 0.024 14.9 1.0 0.59 10.5 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 KKK25418.1 - 0.064 13.6 0.2 9.7 6.6 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 KKK25418.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Peptidase_C14 PF00656.17 KKK25419.1 - 9e-73 245.0 0.0 1.1e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KKK25419.1 - 0.04 13.7 0.2 0.26 11.1 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain PAT1 PF09770.4 KKK25419.1 - 9.9 4.2 9.2 16 3.5 6.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cpn60_TCP1 PF00118.19 KKK25420.1 - 6.5e-141 470.2 3.8 7.5e-141 470.0 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.6 KKK25420.1 - 0.005 16.7 0.1 0.095 12.6 0.0 2.6 2 0 0 2 2 2 1 Replication factor C C-terminal domain DUF367 PF04034.8 KKK25421.1 - 2.1e-29 101.7 0.2 3.2e-29 101.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) Gon7 PF08738.5 KKK25422.1 - 0.0032 17.4 2.3 0.26 11.2 0.3 2.4 2 0 0 2 2 2 2 Gon7 family Neur_chan_memb PF02932.11 KKK25422.1 - 0.087 12.6 1.0 0.11 12.3 0.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-CCHC PF00098.18 KKK25422.1 - 0.51 10.3 3.4 0.24 11.3 0.9 1.6 1 1 0 1 1 1 0 Zinc knuckle DUF4600 PF15372.1 KKK25422.1 - 3.3 7.9 7.4 3 8.0 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) LRR_6 PF13516.1 KKK25423.1 - 5.4e-05 22.8 0.4 0.45 10.7 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 KKK25423.1 - 0.0017 17.9 2.1 0.3 10.7 0.3 3.7 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KKK25423.1 - 0.0026 17.5 1.1 1.9 8.8 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.1 KKK25423.1 - 0.014 15.1 2.2 3.2 7.5 0.9 3.8 2 1 2 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 KKK25423.1 - 0.022 14.8 0.6 5.8 7.5 0.0 4.5 5 0 0 5 5 5 0 Leucine rich repeat Sugar_tr PF00083.19 KKK25424.1 - 2.8e-27 95.4 8.8 3.2e-27 95.2 6.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25424.1 - 0.0033 16.1 0.7 0.0037 16.0 0.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KKK25424.1 - 0.17 11.3 4.7 0.25 10.8 3.3 1.2 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 PRK PF00485.13 KKK25425.1 - 2.1e-51 174.2 0.1 9e-51 172.1 0.0 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KKK25425.1 - 2.3e-41 141.2 0.0 6.5e-41 139.8 0.0 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KKK25425.1 - 4.8e-08 33.8 0.0 1.6e-07 32.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK25425.1 - 2.3e-06 27.9 0.0 8.5e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 KKK25425.1 - 3e-05 23.7 0.0 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 KKK25425.1 - 0.013 15.1 0.2 0.58 9.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pribosyltran PF00156.22 KKK25425.1 - 0.017 14.8 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Zeta_toxin PF06414.7 KKK25425.1 - 0.018 14.1 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KKK25425.1 - 0.034 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KKK25425.1 - 0.073 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.12 KKK25425.1 - 0.088 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 TIP49 PF06068.8 KKK25425.1 - 0.098 11.3 0.1 0.17 10.5 0.1 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_22 PF13401.1 KKK25425.1 - 0.1 12.7 0.0 0.92 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 KKK25425.1 - 0.12 12.4 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.15 KKK25425.1 - 0.14 11.7 0.1 0.97 9.0 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_5 PF07728.9 KKK25425.1 - 0.15 11.8 0.0 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KKK25425.1 - 0.2 11.9 0.8 1.5 9.1 0.2 2.2 2 0 0 2 2 2 0 ABC transporter CLTH PF10607.4 KKK25426.1 - 2.3e-30 105.1 0.1 2.9e-30 104.8 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KKK25426.1 - 4.3e-08 32.6 0.0 7.7e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 LisH NUC153 PF08159.7 KKK25427.1 - 9.2e-13 47.5 4.7 2.1e-12 46.4 0.2 3.3 3 0 0 3 3 3 1 NUC153 domain RRM_6 PF14259.1 KKK25427.1 - 0.0045 16.9 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FNIP_N PF14636.1 KKK25428.1 - 0.00014 22.3 0.2 0.00014 22.3 0.1 4.5 2 2 0 2 2 2 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 KKK25428.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain Glyco_hydro_31 PF01055.21 KKK25429.1 - 3.3e-109 365.6 2.5 3e-107 359.1 1.7 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KKK25429.1 - 3.2e-21 74.9 0.8 1.4e-19 69.7 0.2 3.1 3 0 0 3 3 3 1 Galactose mutarotase-like 60KD_IMP PF02096.15 KKK25430.1 - 5.3e-16 58.8 0.0 1.1e-15 57.8 0.0 1.5 1 1 0 1 1 1 1 60Kd inner membrane protein zf-H2C2_2 PF13465.1 KKK25431.1 - 1.7e-13 50.1 8.0 5.3e-08 32.7 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KKK25431.1 - 3.2e-12 46.0 13.3 7.4e-06 26.0 2.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK25431.1 - 2.2e-10 40.0 13.8 0.00014 21.9 3.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KKK25431.1 - 0.00016 21.7 2.1 0.04 14.1 0.4 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK25431.1 - 0.00058 19.9 12.2 0.06 13.5 0.4 3.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 KKK25431.1 - 0.18 11.5 0.6 0.35 10.6 0.4 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like LIM PF00412.17 KKK25431.1 - 0.69 10.0 3.6 3.2 7.9 2.5 2.0 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 KKK25431.1 - 3.5 7.6 9.6 23 5.0 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 KKK25431.1 - 3.6 7.4 5.8 6.8 6.5 1.4 2.4 1 1 1 2 2 2 0 BED zinc finger Glycos_transf_1 PF00534.15 KKK25432.1 - 1.7e-14 53.5 0.0 3.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KKK25432.1 - 2.3e-09 37.5 0.1 8.7e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KKK25432.1 - 0.0012 18.5 0.0 0.0035 17.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KKK25432.1 - 0.0057 16.8 0.1 0.017 15.2 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KKK25432.1 - 0.02 15.1 0.1 0.042 14.1 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 MRI PF15325.1 KKK25432.1 - 0.043 14.7 1.5 0.088 13.7 1.1 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection Glyco_hydro_53 PF07745.8 KKK25433.1 - 3e-61 207.0 0.0 3.4e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_cc PF11790.3 KKK25433.1 - 0.04 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core NAD_binding_7 PF13241.1 KKK25436.1 - 1.2e-32 112.1 0.0 1.9e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KKK25436.1 - 7.7e-30 102.0 0.0 1.2e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KKK25436.1 - 1.9e-15 55.5 0.1 3.2e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TrkA_N PF02254.13 KKK25436.1 - 0.019 14.9 0.1 0.042 13.8 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KKK25436.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sec7 PF01369.15 KKK25437.1 - 2.5e-64 216.4 0.8 7.4e-64 214.9 0.5 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KKK25437.1 - 1.5e-55 187.1 9.0 1.5e-55 187.1 6.3 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KKK25437.1 - 1e-32 111.4 3.0 6e-31 105.8 0.1 3.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) Ldh_1_N PF00056.18 KKK25438.1 - 7.5e-44 148.9 0.0 6e-43 146.0 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KKK25438.1 - 1.8e-42 145.0 0.0 2.9e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KKK25438.1 - 0.0011 17.6 0.0 0.0016 17.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KKK25438.1 - 0.023 14.9 0.3 0.49 10.7 0.0 2.7 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KKK25438.1 - 0.057 12.4 0.1 0.54 9.3 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-oxoacid_dh PF00198.18 KKK25440.1 - 2.4e-78 262.5 0.1 3.2e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KKK25440.1 - 5.8e-17 61.1 2.3 1.4e-16 59.8 0.3 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 KKK25440.1 - 2e-13 49.7 0.7 4.8e-13 48.5 0.5 1.7 1 0 0 1 1 1 1 e3 binding domain V-SNARE_C PF12352.3 KKK25441.1 - 4.7e-16 58.6 0.4 1.3e-15 57.2 0.3 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KKK25441.1 - 0.0002 21.0 0.0 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 1 Sec20 GRA6 PF05084.8 KKK25441.1 - 0.0034 16.9 1.3 0.0084 15.6 0.9 1.6 1 0 0 1 1 1 1 Granule antigen protein (GRA6) BAR_2 PF10455.4 KKK25441.1 - 0.0089 14.9 0.0 0.0089 14.9 0.0 1.6 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking She9_MDM33 PF05546.6 KKK25441.1 - 0.021 14.3 0.2 0.021 14.3 0.1 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family Sigma70_r4 PF04545.11 KKK25441.1 - 0.034 13.4 0.3 0.078 12.3 0.2 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_MLP1_2 PF07926.7 KKK25441.1 - 0.69 9.6 8.9 0.26 11.0 1.1 2.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CPSF100_C PF13299.1 KKK25441.1 - 0.87 9.7 5.7 0.26 11.4 0.6 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PP28 PF10252.4 KKK25441.1 - 3.3 7.7 11.6 0.072 13.1 1.4 2.6 2 1 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Pribosyltran_N PF13793.1 KKK25443.1 - 4.4e-44 148.9 0.1 5.7e-41 138.8 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KKK25443.1 - 1.9e-35 122.3 0.1 1.4e-30 106.3 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KKK25443.1 - 8.5e-06 25.5 0.0 0.00023 20.8 0.1 2.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DUF1115 PF06544.7 KKK25444.1 - 2.3e-19 69.3 0.0 3.9e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) COX6B PF02297.12 KKK25445.1 - 5.9e-11 42.2 0.3 6.7e-11 42.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KKK25445.1 - 0.029 14.2 0.1 0.043 13.7 0.1 1.4 1 1 0 1 1 1 0 CHCH domain tRNA-synt_2 PF00152.15 KKK25446.1 - 3.3e-73 246.3 0.5 6.2e-73 245.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KKK25446.1 - 1.6e-05 24.6 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain BcsB PF03170.8 KKK25446.1 - 0.069 11.1 0.1 0.1 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit DUF935 PF06074.7 KKK25447.1 - 0.12 11.0 0.1 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Ecl1 PF12855.2 KKK25448.1 - 3.5e-16 58.1 1.0 5.6e-16 57.5 0.7 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 KKK25448.1 - 0.0012 18.0 1.1 0.0024 17.1 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF581) zf-MYND PF01753.13 KKK25448.1 - 0.011 15.5 0.4 0.022 14.6 0.3 1.4 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.4 KKK25448.1 - 2.1 8.1 4.7 1.6 8.5 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Mannitol_dh_C PF08125.8 KKK25456.1 - 2e-48 164.7 0.1 2.7e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KKK25456.1 - 2.2e-15 56.9 0.2 1.4e-14 54.3 0.0 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain ECH PF00378.15 KKK25457.1 - 3.5e-11 42.7 0.6 4.6e-11 42.3 0.4 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1838 PF08894.6 KKK25457.1 - 0.01 15.0 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) DUF1731 PF08338.6 KKK25457.1 - 0.13 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Ribosomal_S17e PF00833.13 KKK25458.1 - 2.4e-58 195.2 1.1 2.8e-58 195.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KKK25458.1 - 0.044 14.4 0.1 0.063 13.9 0.1 1.4 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 KKK25459.1 - 3.7e-98 328.6 0.2 5.5e-98 328.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Epimerase PF01370.16 KKK25459.1 - 1.4e-16 60.6 0.0 2.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK25459.1 - 6.4e-11 41.4 0.0 9.7e-11 40.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KKK25459.1 - 1.1e-07 30.9 0.0 2.5e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KKK25459.1 - 1.6e-07 31.5 0.0 3.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KKK25459.1 - 2.7e-05 24.1 0.0 7.6e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK25459.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 KR domain UPF0184 PF03670.8 KKK25459.1 - 0.034 14.3 0.6 0.081 13.1 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) RPAP2_Rtr1 PF04181.8 KKK25460.1 - 9.3e-19 67.3 0.0 1.6e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family A2M_N_2 PF07703.9 KKK25460.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family N-terminal region ThiF PF00899.16 KKK25462.1 - 7.3e-42 142.4 0.0 1.8e-41 141.1 0.0 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KKK25462.1 - 1.6e-29 101.2 0.0 5.5e-29 99.5 0.2 1.8 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KKK25462.1 - 8.3e-23 80.3 0.4 8.3e-23 80.3 0.3 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KKK25462.1 - 2.3e-21 74.9 8.0 3.7e-21 74.2 1.5 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 KKK25462.1 - 0.00044 20.4 0.1 0.0023 18.1 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KKK25462.1 - 0.008 16.2 0.0 0.034 14.2 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KKK25462.1 - 0.096 13.1 0.0 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Seryl_tRNA_N PF02403.17 KKK25462.1 - 2.3 8.2 6.4 1.6 8.7 0.0 3.1 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2419 PF10343.4 KKK25463.1 - 2.5e-145 483.1 0.0 3.2e-145 482.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1563 PF07599.6 KKK25463.1 - 0.18 11.6 0.8 0.34 10.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) tRNA_int_end_N2 PF12928.2 KKK25464.1 - 5.4e-36 121.8 0.0 1e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term adh_short PF00106.20 KKK25464.1 - 2.4e-24 86.1 0.0 4.3e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KKK25464.1 - 1.3e-10 41.4 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK25464.1 - 1.9e-09 37.4 0.0 9.4e-09 35.1 0.0 2.1 1 1 0 1 1 1 1 KR domain tRNA_int_endo_N PF02778.9 KKK25464.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Shikimate_DH PF01488.15 KKK25464.1 - 0.018 15.1 0.0 0.11 12.6 0.0 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KKK25464.1 - 0.036 13.4 0.1 17 4.7 0.0 3.2 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family APH PF01636.18 KKK25465.1 - 4e-15 56.2 0.0 9.1e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KKK25465.1 - 0.0036 16.0 0.0 0.0081 14.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 KKK25465.1 - 0.0052 16.3 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Sigma_1_2 PF03084.9 KKK25465.1 - 0.0054 15.4 0.0 0.0087 14.7 0.0 1.2 1 0 0 1 1 1 1 Reoviral Sigma1/Sigma2 family Kdo PF06293.9 KKK25465.1 - 0.0075 15.3 0.0 0.42 9.6 0.0 2.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SBDS_C PF09377.5 KKK25474.1 - 4.3e-51 171.8 0.0 6.5e-51 171.2 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KKK25474.1 - 2.5e-26 91.2 0.1 6.4e-26 89.9 0.1 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.17 KKK25475.1 - 8.6e-10 38.3 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KKK25475.1 - 4.1e-07 30.1 0.0 5.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Peptidase_S10 PF00450.17 KKK25476.1 - 3.1e-97 326.3 0.0 3.4e-97 326.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KKK25476.1 - 0.00027 20.8 0.0 0.0094 15.8 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ribosomal_S13 PF00416.17 KKK25477.1 - 7.1e-23 81.0 0.5 8.4e-23 80.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PALP PF00291.20 KKK25478.1 - 4e-39 134.6 0.6 4.7e-39 134.4 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DC_STAMP PF07782.8 KKK25483.1 - 0.0043 16.7 0.0 0.0043 16.7 0.0 1.0 1 0 0 1 1 1 1 DC-STAMP-like protein Baculo_E56 PF04639.7 KKK25483.1 - 0.048 12.3 1.8 0.054 12.1 1.3 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope SpoIIIAH PF12685.2 KKK25483.1 - 0.096 12.1 0.0 0.098 12.1 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein TMEMspv1-c74-12 PF11044.3 KKK25483.1 - 0.14 11.7 0.4 0.19 11.3 0.3 1.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein NVEALA PF14055.1 KKK25483.1 - 0.77 9.5 2.4 0.94 9.2 1.7 1.3 1 1 0 1 1 1 0 NVEALA protein DUF3719 PF12516.3 KKK25520.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) DUF2393 PF09624.5 KKK25520.1 - 0.22 11.0 2.1 0.49 9.9 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2393) DUF3984 PF13136.1 KKK25521.1 - 4.1e-101 338.4 26.7 4.1e-101 338.4 18.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) Nop14 PF04147.7 KKK25521.1 - 0.0051 14.8 6.8 0.0068 14.4 4.7 1.2 1 0 0 1 1 1 1 Nop14-like family Glycoprotein PF03409.10 KKK25521.1 - 4.1 6.0 8.5 6.9 5.2 5.9 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein OTCace_N PF02729.16 KKK25522.1 - 5.6e-43 145.9 0.0 1.1e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KKK25522.1 - 1.5e-40 138.6 0.0 2.4e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SNARE PF05739.14 KKK25523.1 - 3.5e-18 65.0 3.0 1.1e-17 63.4 2.1 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KKK25523.1 - 8.4e-12 45.1 2.9 1.4e-11 44.4 0.2 2.3 2 0 0 2 2 2 1 Syntaxin DUF948 PF06103.6 KKK25523.1 - 0.53 10.1 2.8 4.9 7.0 0.0 3.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.16 KKK25523.1 - 0.56 9.7 8.8 0.14 11.6 1.3 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SlyX PF04102.7 KKK25523.1 - 0.62 10.4 8.6 5.1 7.5 0.2 3.4 3 1 1 4 4 4 0 SlyX Syntaxin_2 PF14523.1 KKK25523.1 - 2.1 8.4 11.2 1.9 8.5 0.3 3.1 2 1 1 3 3 3 0 Syntaxin-like protein CTD_bind PF04818.8 KKK25524.1 - 3.3e-21 75.2 0.4 6.3e-21 74.3 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 KKK25524.1 - 0.05 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) DUF3635 PF12330.3 KKK25525.1 - 5.3e-06 26.4 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) ABC_membrane PF00664.18 KKK25526.1 - 1.4e-42 146.0 10.1 1.7e-42 145.7 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KKK25526.1 - 2.7e-35 121.6 0.0 6.8e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KKK25526.1 - 6.1e-05 23.1 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KKK25526.1 - 0.00038 19.7 0.5 0.024 13.8 0.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KKK25526.1 - 0.0024 17.3 0.0 0.0068 15.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK25526.1 - 0.0044 17.1 0.1 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK25526.1 - 0.0076 17.0 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KKK25526.1 - 0.012 15.0 0.1 0.2 11.0 0.0 2.6 2 1 1 3 3 3 0 IstB-like ATP binding protein ABC_ATPase PF09818.4 KKK25526.1 - 0.012 14.2 0.4 0.052 12.1 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_16 PF13191.1 KKK25526.1 - 0.017 15.1 0.7 0.1 12.5 0.5 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 KKK25526.1 - 0.035 13.5 0.2 0.16 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KKK25526.1 - 0.047 13.8 0.0 0.24 11.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KKK25526.1 - 0.061 13.2 2.6 0.14 12.0 0.4 2.7 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KKK25526.1 - 0.092 13.0 0.1 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KKK25526.1 - 0.1 11.7 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KKK25526.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Nucleoside_tran PF01733.13 KKK25527.1 - 4e-47 160.8 20.7 4.3e-47 160.7 9.5 2.5 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 KKK25527.1 - 0.00014 20.7 37.0 0.00029 19.6 16.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Clathrin_lg_ch PF01086.12 KKK25528.1 - 2.5e-77 259.7 2.1 2.9e-77 259.6 1.5 1.0 1 0 0 1 1 1 1 Clathrin light chain CDC37_N PF03234.9 KKK25529.1 - 2.5e-61 207.0 5.7 2.5e-61 207.0 4.0 2.7 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KKK25529.1 - 2.7e-49 166.9 0.2 8.7e-49 165.3 0.2 1.9 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KKK25529.1 - 2.6e-27 94.6 1.6 9.9e-27 92.7 1.1 2.0 1 0 0 1 1 1 1 Cdc37 C terminal domain DUF3887 PF13026.1 KKK25529.1 - 0.062 13.5 0.4 0.062 13.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3887) EF-hand_1 PF00036.27 KKK25530.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KKK25530.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KKK25530.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KKK25530.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KKK25530.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KKK25530.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KKK25530.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KKK25530.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KKK25530.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KKK25530.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KKK25530.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KKK25530.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 KKK25530.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 KKK25530.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 KKK25530.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 KKK25530.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 KKK25530.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 KKK25530.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 KKK25530.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain Med20 PF08612.6 KKK25531.1 - 4.2e-95 317.1 0.0 4.8e-95 316.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Glyco_hydro_47 PF01532.15 KKK25532.1 - 3e-178 593.1 0.0 3.4e-178 592.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 KKK25532.1 - 0.027 12.7 0.0 1.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Lysis_S PF04971.7 KKK25533.1 - 0.23 11.1 1.1 0.6 9.8 0.2 2.2 2 0 0 2 2 2 0 Lysis protein S AA_permease_2 PF13520.1 KKK25534.1 - 4.3e-52 177.0 51.5 5.5e-52 176.7 35.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK25534.1 - 1.6e-23 82.7 47.0 2.2e-23 82.3 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease APH PF01636.18 KKK25535.1 - 3.4e-13 49.8 0.5 1.4e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Alpha-amylase PF00128.19 KKK25536.1 - 2.1e-71 240.8 2.2 2.8e-71 240.4 1.5 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KKK25536.1 - 6e-33 112.7 0.1 1.3e-32 111.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_31 PF01055.21 KKK25536.1 - 0.00014 20.8 0.6 0.00017 20.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Homeobox_KN PF05920.6 KKK25537.1 - 1.3e-17 63.1 0.7 3.9e-17 61.6 0.0 2.2 2 1 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 KKK25537.1 - 0.00043 19.8 1.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 2 Homeobox domain Trp_DMAT PF11991.3 KKK25538.1 - 7.4e-88 295.1 0.0 9.4e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 KKK25539.1 - 1.1e-42 146.1 0.0 1.9e-42 145.4 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 DUF2236 PF09995.4 KKK25539.1 - 0.0071 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Ufm1 PF03671.9 KKK25539.1 - 0.13 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein AMP-binding PF00501.23 KKK25540.1 - 2.5e-158 526.8 0.0 2.1e-81 273.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KKK25540.1 - 7e-66 222.1 0.0 4.4e-40 137.4 0.0 3.0 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KKK25540.1 - 5.5e-15 55.3 0.1 1.2e-07 31.9 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK25540.1 - 1.2e-13 51.7 2.0 1.2e-07 32.5 0.5 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KKK25540.1 - 1.3e-10 41.3 0.0 1e-06 28.9 0.0 3.6 3 0 0 3 3 3 2 HxxPF-repeated domain Aminotran_1_2 PF00155.16 KKK25541.1 - 7.5e-40 136.9 0.0 9.1e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK25541.1 - 0.0034 16.5 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF4585 PF15232.1 KKK25541.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Methyltransf_23 PF13489.1 KKK25542.1 - 4.9e-10 39.3 0.0 6.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK25542.1 - 0.0062 16.1 0.0 1.3 8.6 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KKK25542.1 - 0.015 15.8 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KKK25542.1 - 0.018 15.4 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.9 KKK25543.1 - 6.4e-16 58.8 0.1 9.3e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK25543.1 - 3.8e-06 26.0 0.3 1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KKK25543.1 - 2.2e-05 23.1 0.3 0.00099 17.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KKK25543.1 - 2.3e-05 24.5 0.1 0.00066 19.7 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK25543.1 - 7.3e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KKK25543.1 - 0.00018 20.5 0.2 0.095 11.5 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KKK25543.1 - 0.00023 20.9 0.0 0.069 12.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KKK25543.1 - 0.00038 19.6 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK25543.1 - 0.00083 18.5 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KKK25543.1 - 0.0013 17.7 0.2 0.0028 16.6 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 KKK25543.1 - 0.005 15.8 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KKK25543.1 - 0.089 11.6 0.1 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 KKK25543.1 - 0.11 11.5 0.4 0.16 11.0 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GF_recep_IV PF14843.1 KKK25543.1 - 0.19 11.3 0.4 0.4 10.2 0.1 1.5 2 0 0 2 2 2 0 Growth factor receptor domain IV DUF3632 PF12311.3 KKK25544.1 - 1.8e-39 135.4 0.0 2.6e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Bradykinin PF06753.7 KKK25544.1 - 0.29 10.6 3.4 0.12 11.8 0.5 1.7 2 0 0 2 2 2 0 Bradykinin PAP2 PF01569.16 KKK25545.1 - 8.1e-15 54.6 5.3 8.1e-15 54.6 3.7 2.3 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 KKK25545.1 - 2e-06 27.4 7.0 2e-06 27.4 4.9 1.9 2 1 0 2 2 2 1 PAP2 superfamily Glyco_transf_90 PF05686.7 KKK25546.1 - 3.2e-29 101.8 0.4 4.2e-29 101.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KKK25546.1 - 0.0091 16.2 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ACCA PF03255.9 KKK25546.1 - 0.12 11.8 0.0 0.98 8.9 0.0 2.4 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MU117 PF15474.1 KKK25547.1 - 2.6e-14 53.4 11.0 3.6e-14 53.0 7.6 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family RasGAP PF00616.14 KKK25548.1 - 1.6e-55 187.8 0.1 4.5e-55 186.3 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KKK25548.1 - 1.9e-32 111.8 5.9 1.9e-32 111.8 4.1 2.8 3 0 0 3 3 3 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 KKK25548.1 - 0.033 14.0 0.2 0.084 12.7 0.1 1.6 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain LCAT PF02450.10 KKK25550.1 - 2.6e-93 313.0 0.0 3.1e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase HutD PF05962.6 KKK25550.1 - 0.0098 15.6 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 HutD Acetyltransf_1 PF00583.19 KKK25551.1 - 7.1e-19 67.6 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK25551.1 - 1.2e-11 44.2 0.1 1.9e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK25551.1 - 1.4e-09 38.0 0.0 2.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK25551.1 - 2.3e-09 37.5 0.0 3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK25551.1 - 2.3e-09 37.2 0.0 3.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KKK25551.1 - 1.9e-07 31.0 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK25551.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 KKK25551.1 - 0.00038 19.3 0.1 0.00058 18.7 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.1 KKK25551.1 - 0.00046 20.0 0.0 0.00084 19.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 KKK25551.1 - 0.029 13.9 0.1 0.041 13.4 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KKK25551.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_23 PF13489.1 KKK25552.1 - 7.7e-10 38.7 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK25552.1 - 4.5e-07 29.5 0.0 6.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK25552.1 - 4.4e-06 27.0 0.0 8.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK25552.1 - 0.00055 20.3 0.0 0.00093 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK25552.1 - 0.0057 15.7 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KKK25552.1 - 0.024 15.2 0.0 0.08 13.5 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain GST_N_3 PF13417.1 KKK25553.1 - 1.3e-06 28.5 0.0 3.5e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK25553.1 - 3.4e-06 26.9 0.0 5.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KKK25553.1 - 5.7e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK25553.1 - 0.00018 21.3 0.1 0.00049 19.9 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK25553.1 - 0.01 16.3 0.0 0.022 15.2 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mis14 PF08641.7 KKK25554.1 - 1.5e-30 106.0 6.0 1.5e-30 106.0 4.2 2.7 2 1 1 3 3 3 1 Kinetochore protein Mis14 like BSP_II PF05432.6 KKK25554.1 - 0.00087 18.6 9.2 0.0012 18.1 6.4 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) SRP-alpha_N PF04086.8 KKK25554.1 - 0.0059 16.0 9.2 0.0079 15.6 6.4 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Myc_N PF01056.13 KKK25554.1 - 0.017 14.3 5.3 0.023 13.8 3.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 KKK25554.1 - 0.023 13.2 14.0 0.026 13.0 9.7 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KKK25554.1 - 0.12 10.2 18.9 0.15 9.9 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 KKK25554.1 - 0.14 9.8 5.5 0.15 9.7 3.8 1.0 1 0 0 1 1 1 0 Ycf1 DUF4611 PF15387.1 KKK25554.1 - 0.15 12.1 21.8 0.13 12.4 7.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) TFIIF_alpha PF05793.7 KKK25554.1 - 1.2 7.4 22.7 1.6 6.9 15.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.10 KKK25554.1 - 1.3 7.5 6.8 1.5 7.3 4.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 KKK25554.1 - 2.3 5.7 7.4 3 5.4 5.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 KKK25554.1 - 2.5 6.0 21.5 3.4 5.5 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.4 KKK25554.1 - 2.6 6.6 12.3 3.5 6.2 8.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NARP1 PF12569.3 KKK25554.1 - 2.7 6.6 13.9 4 6.0 9.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sporozoite_P67 PF05642.6 KKK25554.1 - 2.9 5.6 7.3 3.9 5.2 5.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 KKK25554.1 - 3 7.0 8.8 4.2 6.5 6.1 1.3 1 0 0 1 1 1 0 NOA36 protein Apt1 PF10351.4 KKK25554.1 - 3 6.6 10.4 4.2 6.1 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dicty_REP PF05086.7 KKK25554.1 - 3.6 5.2 6.2 5.3 4.6 4.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CRAL_TRIO PF00650.15 KKK25555.1 - 1.3e-37 128.7 0.0 2.2e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK25555.1 - 3.8e-10 39.7 0.6 1.7e-09 37.6 0.1 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KKK25555.1 - 7e-06 26.0 0.0 2.2e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain TMF_DNA_bd PF12329.3 KKK25555.1 - 0.087 12.6 0.0 7.5 6.4 0.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA PF00004.24 KKK25559.1 - 2.1e-11 44.1 0.0 4.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK25559.1 - 2.9e-07 30.6 0.0 7.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KKK25559.1 - 3.7e-05 23.6 0.0 8.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KKK25559.1 - 4.7e-05 22.5 0.0 8.8e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 KKK25559.1 - 4.9e-05 22.2 0.0 9.3e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 KKK25559.1 - 4.9e-05 23.0 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KKK25559.1 - 0.00038 21.2 1.0 0.0018 19.1 0.0 2.7 4 0 0 4 4 2 1 AAA domain Zeta_toxin PF06414.7 KKK25559.1 - 0.0022 17.1 0.0 0.005 15.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KKK25559.1 - 0.0022 17.6 0.0 0.0072 16.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KKK25559.1 - 0.0059 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KKK25559.1 - 0.01 15.0 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK25559.1 - 0.023 14.6 0.0 0.069 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 KKK25559.1 - 0.028 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KKK25559.1 - 0.053 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK25559.1 - 0.07 12.2 0.0 0.68 9.0 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KKK25559.1 - 0.1 12.0 0.1 1.1 8.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 KKK25559.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus YL1 PF05764.8 KKK25560.1 - 0.0031 17.1 3.5 0.0035 16.9 2.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Di19_C PF14571.1 KKK25560.1 - 0.22 11.8 1.7 0.25 11.6 1.2 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal adh_short PF00106.20 KKK25561.1 - 4e-18 65.8 0.0 5.6e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK25561.1 - 1.1e-08 34.9 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 KR domain APH PF01636.18 KKK25562.1 - 1.3e-20 74.1 0.0 6.9e-10 39.0 0.0 4.3 4 1 0 4 4 4 3 Phosphotransferase enzyme family TRAPPC9-Trs120 PF08626.6 KKK25563.1 - 3.6e-150 501.5 0.0 5.9e-150 500.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DIOX_N PF14226.1 KKK25564.1 - 4.6e-33 114.1 0.0 2.9e-30 105.1 0.0 2.4 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK25564.1 - 2e-13 50.4 0.0 5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Beta_helix PF13229.1 KKK25564.1 - 8.2e-08 32.1 10.9 5.5e-06 26.2 4.5 2.6 1 1 1 2 2 2 2 Right handed beta helix region DUF1565 PF07602.6 KKK25564.1 - 0.0097 15.0 0.3 0.018 14.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1565) Chondroitinas_B PF14592.1 KKK25564.1 - 0.028 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Chondroitinase B Glyco_hydro_43 PF04616.9 KKK25565.1 - 3.6e-36 124.7 4.7 4.6e-36 124.3 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 TNF PF00229.13 KKK25565.1 - 0.022 14.2 1.0 4.1 6.9 0.1 2.3 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family C1q PF00386.16 KKK25565.1 - 0.069 13.1 1.1 7.1 6.6 0.1 2.6 2 0 0 2 2 2 0 C1q domain ketoacyl-synt PF00109.21 KKK25566.1 - 1.1e-08 34.8 0.0 1.5e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KKK25567.1 - 2e-52 177.4 0.2 3.7e-52 176.6 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KKK25567.1 - 9.8e-38 129.6 0.3 2.4e-37 128.4 0.2 1.7 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KKK25567.1 - 5.3e-16 58.3 0.0 1.7e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK25567.1 - 3.4e-14 53.8 0.0 3.7e-13 50.4 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KKK25567.1 - 6.6e-10 39.3 0.0 2.7e-09 37.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK25567.1 - 5.4e-09 35.9 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK25567.1 - 4.2e-07 30.3 0.0 1.7e-06 28.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK25567.1 - 5.1e-07 29.3 0.0 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.21 KKK25567.1 - 4.9e-05 22.9 0.0 8.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_18 PF12847.2 KKK25567.1 - 0.00036 21.0 0.0 0.017 15.6 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK25567.1 - 0.00097 18.3 0.0 0.0023 17.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.7 KKK25567.1 - 0.0023 17.6 0.9 0.0061 16.2 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KKK25567.1 - 0.0037 17.4 0.1 0.01 16.0 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_8 PF05148.10 KKK25567.1 - 0.28 10.7 0.2 0.6 9.7 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase PBP_like_2 PF12849.2 KKK25568.1 - 1.1e-09 38.1 5.3 1.5e-09 37.7 3.7 1.1 1 0 0 1 1 1 1 PBP superfamily domain Metallophos PF00149.23 KKK25569.1 - 1.7e-08 34.1 0.0 5.2e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK25569.1 - 2.4e-05 24.1 0.0 0.0001 22.1 0.0 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Alpha-L-AF_C PF06964.7 KKK25570.1 - 2.6e-42 144.5 0.0 4.3e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Tbf5 PF06331.7 KKK25572.1 - 7.4e-22 76.9 0.6 7.4e-22 76.9 0.4 1.9 2 0 0 2 2 2 1 Transcription factor TFIIH complex subunit Tfb5 AAR2 PF05282.6 KKK25572.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 AAR2 protein Fungal_trans PF04082.13 KKK25573.1 - 1.2e-15 57.0 0.2 9e-15 54.2 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25573.1 - 2.9e-08 33.4 10.2 5.3e-08 32.6 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.7 KKK25573.1 - 0.15 12.4 1.1 0.4 11.0 0.0 2.2 2 0 0 2 2 2 0 SlyX Cu_amine_oxid PF01179.15 KKK25574.1 - 6.5e-162 538.9 0.0 7.9e-162 538.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KKK25574.1 - 5.5e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KKK25574.1 - 2.9e-05 24.0 0.1 6.4e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DJ-1_PfpI PF01965.19 KKK25575.1 - 3e-15 55.9 0.0 5.4e-15 55.1 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KKK25575.1 - 0.0001 21.7 0.0 0.00024 20.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family HSP20 PF00011.16 KKK25576.1 - 1.1e-18 66.9 1.2 5.1e-16 58.3 0.9 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family N-SET PF11764.3 KKK25576.1 - 0.073 12.9 0.1 0.099 12.5 0.1 1.2 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N E1-E2_ATPase PF00122.15 KKK25578.1 - 2.1e-50 170.9 4.6 2.1e-50 170.9 3.2 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK25578.1 - 3.2e-28 98.4 2.4 3.2e-28 98.4 1.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KKK25578.1 - 1.2e-16 60.4 0.0 2.5e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KKK25578.1 - 1.6e-14 54.8 0.0 6.1e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK25578.1 - 2.4e-07 31.1 0.0 4.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK25578.1 - 1e-06 28.0 0.4 6.4e-06 25.5 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus MFS_1 PF07690.11 KKK25580.1 - 9.9e-21 73.8 23.6 9.9e-21 73.8 16.4 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK25580.1 - 3.8e-05 22.4 27.8 0.0003 19.4 19.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_M56 PF05569.6 KKK25580.1 - 0.098 11.6 1.8 0.16 10.9 0.1 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 p450 PF00067.17 KKK25581.1 - 2.1e-44 151.8 0.0 2.9e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 KKK25582.1 - 9.8e-71 239.0 0.0 1.4e-70 238.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK25582.1 - 3.8e-07 29.8 0.1 1.8e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 KKK25583.1 - 1.3e-37 129.3 49.9 7e-37 126.9 34.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK25583.1 - 0.00015 20.1 23.6 0.0003 19.1 16.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2937 PF11157.3 KKK25583.1 - 0.0036 16.6 2.6 0.026 13.8 0.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2937) Epimerase PF01370.16 KKK25585.1 - 4.6e-11 42.5 0.0 1.3e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK25585.1 - 5.1e-07 29.8 0.0 8.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KKK25585.1 - 4.8e-06 25.6 0.5 0.00091 18.2 0.1 2.9 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KKK25585.1 - 1.7e-05 23.6 0.0 0.00011 21.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KKK25585.1 - 0.0029 16.5 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KKK25585.1 - 0.004 16.4 0.0 0.0064 15.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KKK25585.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AA_permease PF00324.16 KKK25586.1 - 2.9e-141 471.0 39.1 3.3e-141 470.9 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK25586.1 - 3.7e-39 134.4 39.4 4.8e-39 134.0 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease CATSPERD PF15020.1 KKK25586.1 - 2.8 5.8 4.5 8.7 4.2 0.0 2.1 2 0 0 2 2 2 0 Cation channel sperm-associated protein subunit delta Fungal_trans_2 PF11951.3 KKK25587.1 - 8.9e-08 31.1 1.4 1.8e-06 26.8 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25587.1 - 9.3e-07 28.6 11.2 1.5e-06 28.0 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4381 PF14316.1 KKK25587.1 - 0.17 11.9 4.4 6.4 6.8 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) MIP PF00230.15 KKK25588.1 - 1.1e-40 139.5 6.6 1.5e-40 139.0 4.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1212 PF06738.7 KKK25588.1 - 2 7.8 4.3 12 5.3 2.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) Pectate_lyase PF03211.8 KKK25589.1 - 8.9e-61 205.0 2.7 1.2e-60 204.6 1.9 1.0 1 0 0 1 1 1 1 Pectate lyase Transferase PF02458.10 KKK25590.1 - 3e-07 29.2 0.0 0.00018 20.0 0.0 2.2 2 1 0 2 2 2 2 Transferase family AA_permease_2 PF13520.1 KKK25592.1 - 4.6e-64 216.5 34.5 5.6e-64 216.2 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK25592.1 - 6.5e-15 54.4 32.3 8.1e-15 54.1 22.4 1.0 1 0 0 1 1 1 1 Amino acid permease HsbA PF12296.3 KKK25593.1 - 1.3e-24 86.4 6.8 2e-24 85.8 4.7 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A MAPEG PF01124.13 KKK25595.1 - 1.1e-14 54.0 1.7 1.6e-14 53.6 1.2 1.1 1 0 0 1 1 1 1 MAPEG family Flp_Fap PF04964.9 KKK25595.1 - 0.085 12.4 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Flp/Fap pilin component FA_desaturase PF00487.19 KKK25603.1 - 1.5e-37 129.4 30.2 2.3e-37 128.8 20.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KKK25603.1 - 5.7e-12 45.2 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DFP PF04127.10 KKK25604.1 - 2.9e-11 43.3 0.0 3.9e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Fringe PF02434.11 KKK25605.1 - 1.6e-09 37.3 0.0 2.7e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Fringe-like Glyco_transf_29 PF00777.13 KKK25606.1 - 0.03 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) CENP-O PF09496.5 KKK25608.1 - 2.8e-27 94.7 0.0 5.8e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Sfi1_C PF10638.4 KKK25608.1 - 0.088 13.2 0.2 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Spindle body associated protein C-terminus Abhydrolase_3 PF07859.8 KKK25610.1 - 1.2e-41 142.5 0.0 1.5e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK25610.1 - 2.4e-08 33.4 0.0 8.1e-08 31.7 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KKK25610.1 - 6e-07 29.5 0.1 2.4e-06 27.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK25610.1 - 5.9e-06 26.1 0.0 8.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KKK25610.1 - 3.8e-05 23.0 0.0 0.05 12.8 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KKK25610.1 - 0.0014 18.0 0.0 0.0046 16.4 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KKK25610.1 - 0.0033 15.9 0.0 1.4 7.3 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KKK25610.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.23 KKK25610.1 - 0.029 13.1 0.0 0.06 12.0 0.0 1.4 1 1 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.11 KKK25610.1 - 0.03 13.7 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Acatn PF13000.2 KKK25611.1 - 4e-149 497.6 21.4 2.2e-76 257.5 5.3 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Sugar_tr PF00083.19 KKK25618.1 - 8.3e-91 304.8 23.1 1.1e-90 304.3 16.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25618.1 - 6.6e-15 54.6 39.9 7.6e-09 34.7 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KKK25619.1 - 3.4e-54 183.9 0.0 5.7e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25619.1 - 2.2e-05 24.2 3.8 4.8e-05 23.1 2.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF678 PF05077.7 KKK25619.1 - 0.15 12.0 2.1 0.35 10.8 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Mannosyl_trans3 PF11051.3 KKK25620.1 - 3.2e-77 259.5 0.0 8.8e-77 258.0 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative FKBP_C PF00254.23 KKK25623.1 - 2.5e-32 110.7 0.0 2.9e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Dynamin_M PF01031.15 KKK25624.1 - 1.9e-105 351.8 1.0 2.6e-105 351.4 0.1 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KKK25624.1 - 2.5e-56 190.0 0.1 5e-56 189.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KKK25624.1 - 1.3e-28 98.7 4.5 1.3e-28 98.7 3.1 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KKK25624.1 - 0.00015 21.7 0.2 0.0013 18.6 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.4 KKK25624.1 - 0.0022 17.1 0.7 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2226) Miro PF08477.8 KKK25624.1 - 0.01 16.3 0.0 0.064 13.7 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein FeoB_N PF02421.13 KKK25624.1 - 0.092 12.0 0.4 17 4.6 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B BCIP PF13862.1 KKK25634.1 - 2.7e-75 252.1 0.0 3.7e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CM_2 PF01817.16 KKK25635.1 - 1.6e-10 40.9 0.1 5.7e-06 26.3 0.0 3.2 2 1 0 2 2 2 2 Chorismate mutase type II DDR PF08841.5 KKK25636.1 - 0.12 11.2 0.0 2.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.15 KKK25636.1 - 0.2 9.5 0.0 0.4 8.5 0.0 1.4 1 0 0 1 1 1 0 Hsp70 protein WD40 PF00400.27 KKK25637.1 - 6.7e-38 127.2 9.9 8.1e-10 38.1 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KKK25637.1 - 8.2e-08 30.8 10.8 0.0046 15.1 0.8 4.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 APG6 PF04111.7 KKK25637.1 - 0.0074 15.3 1.0 0.012 14.6 0.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 PQQ_2 PF13360.1 KKK25637.1 - 0.042 13.3 0.6 1 8.7 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain AAA_23 PF13476.1 KKK25637.1 - 0.43 10.8 1.7 0.7 10.1 1.2 1.2 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KKK25637.1 - 0.48 10.0 5.0 0.85 9.1 3.5 1.4 1 0 0 1 1 1 0 IncA protein Spc24 PF08286.6 KKK25637.1 - 0.65 9.6 4.1 0.25 11.0 0.8 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Sad1_UNC PF07738.8 KKK25638.1 - 1.5e-12 47.4 0.0 1.2e-06 28.3 0.0 2.7 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal Mid2 PF04478.7 KKK25639.1 - 0.00021 20.7 0.3 0.00036 19.9 0.2 1.4 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 KKK25639.1 - 0.019 14.2 0.0 0.019 14.2 0.0 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain SSP160 PF06933.6 KKK25639.1 - 0.13 10.1 10.4 0.17 9.8 7.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SAM_2 PF07647.12 KKK25640.1 - 4.4e-16 58.4 0.0 2.2e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.18 KKK25640.1 - 1.4e-14 54.2 0.0 3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 KKK25640.1 - 6.1e-12 45.5 0.0 2.1e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Angiomotin_C PF12240.3 KKK25640.1 - 0.048 13.1 0.2 0.084 12.3 0.2 1.3 1 0 0 1 1 1 0 Angiomotin C terminal Nha1_C PF08619.5 KKK25641.1 - 1.3e-96 324.5 20.1 2.6e-96 323.5 13.9 1.5 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 KKK25641.1 - 2.9e-69 233.4 17.5 3.7e-69 233.0 12.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF21 PF01595.15 KKK25641.1 - 0.83 8.9 10.6 0.061 12.6 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF21 Kri1_C PF12936.2 KKK25642.1 - 5.1e-31 106.4 0.5 5.1e-31 106.4 0.4 3.7 2 1 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.7 KKK25642.1 - 1.4e-27 95.8 16.7 1.4e-27 95.8 11.6 4.6 5 1 1 6 6 6 1 KRI1-like family CRISPR_Cse2 PF09485.5 KKK25642.1 - 0.028 14.4 1.0 0.028 14.4 0.7 2.0 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Mito_carr PF00153.22 KKK25643.1 - 1.4e-65 217.0 5.9 1.1e-23 82.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sen15 PF09631.5 KKK25644.1 - 3.9e-10 39.8 0.0 2.9e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Sen15 protein PH PF00169.24 KKK25645.1 - 4.5e-08 33.2 0.0 1.7e-07 31.3 0.0 2.1 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 KKK25645.1 - 0.00089 18.7 0.0 0.0022 17.4 0.0 1.7 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 KKK25645.1 - 0.0094 16.1 3.9 5.3 7.3 0.0 3.6 2 1 0 2 2 2 2 Pleckstrin homology domain bPH_3 PF14470.1 KKK25645.1 - 0.064 13.5 0.0 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial PH domain JmjN PF02375.12 KKK25645.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 jmjN domain DPBB_1 PF03330.13 KKK25662.1 - 4.3e-06 26.6 0.0 2.5e-05 24.1 0.0 2.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel TFIIA PF03153.8 KKK25662.1 - 0.82 9.4 14.7 0.97 9.2 10.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TcpE PF12648.2 KKK25663.1 - 0.029 14.5 1.3 0.037 14.1 0.9 1.1 1 0 0 1 1 1 0 TcpE family Hexapep PF00132.19 KKK25680.1 - 1.2e-14 53.0 8.0 5.8e-11 41.3 2.9 3.6 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 KKK25680.1 - 2.1e-14 53.2 0.2 3.3e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 KKK25680.1 - 1.8e-11 43.3 8.1 7.8e-10 38.1 2.3 3.4 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase ABC_membrane PF00664.18 KKK25681.1 - 7.6e-79 264.9 21.7 2e-46 158.6 2.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KKK25681.1 - 4e-61 205.3 0.0 1.1e-29 103.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KKK25681.1 - 3.3e-16 59.2 1.5 6.4e-05 22.2 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KKK25681.1 - 3.7e-09 35.9 0.1 0.0015 17.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KKK25681.1 - 7.7e-08 32.6 0.0 0.49 10.3 0.0 4.6 3 1 0 4 4 4 1 AAA domain AAA_17 PF13207.1 KKK25681.1 - 4.6e-07 30.6 0.0 0.055 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK25681.1 - 6.6e-07 29.5 1.9 0.11 12.6 0.1 4.4 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK25681.1 - 1.2e-06 28.6 2.7 0.017 15.1 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KKK25681.1 - 2e-05 23.8 0.0 0.033 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 KKK25681.1 - 2.1e-05 24.4 0.4 0.0058 16.4 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.1 KKK25681.1 - 3.9e-05 24.0 3.4 0.12 12.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KKK25681.1 - 0.00011 21.8 0.3 2.5 7.6 0.0 4.2 4 0 0 4 4 4 1 AAA domain APS_kinase PF01583.15 KKK25681.1 - 0.00014 21.5 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.1 KKK25681.1 - 0.00018 21.7 0.0 0.86 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KKK25681.1 - 0.00024 21.0 0.0 0.82 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KKK25681.1 - 0.00032 19.4 1.1 0.032 12.8 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_19 PF13245.1 KKK25681.1 - 0.00043 19.9 0.1 0.51 10.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 KKK25681.1 - 0.001 19.2 0.9 9.5 6.4 0.2 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KKK25681.1 - 0.0011 18.5 1.0 0.29 10.5 0.0 3.2 4 0 0 4 4 4 1 AAA-like domain Zeta_toxin PF06414.7 KKK25681.1 - 0.0014 17.7 0.0 0.4 9.7 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin SbcCD_C PF13558.1 KKK25681.1 - 0.003 17.4 0.3 5.7 6.9 0.1 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KKK25681.1 - 0.0082 15.5 3.9 1.7 7.9 0.0 4.0 5 0 0 5 5 4 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK25681.1 - 0.02 14.3 0.0 0.31 10.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 KKK25681.1 - 0.049 13.5 0.0 17 5.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.15 KKK25681.1 - 0.055 12.1 2.3 7.8 5.0 0.0 3.0 3 0 0 3 3 3 0 G-protein alpha subunit KdpD PF02702.12 KKK25681.1 - 0.062 12.4 0.0 0.56 9.3 0.0 2.2 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain DUF3987 PF13148.1 KKK25681.1 - 0.066 11.7 5.4 2 6.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_5 PF07728.9 KKK25681.1 - 0.072 12.8 0.0 14 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KKK25681.1 - 0.099 12.6 0.0 20 5.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Nucleoplasmin PF03066.10 KKK25681.1 - 0.26 10.7 5.4 0.49 9.9 3.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 KKK25681.1 - 0.3 11.4 10.5 1.2 9.5 7.3 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.5 KKK25681.1 - 0.82 9.9 6.0 2.2 8.5 4.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DDHD PF02862.12 KKK25681.1 - 1.2 8.9 2.9 2.8 7.6 2.0 1.6 1 0 0 1 1 1 0 DDHD domain MFS_1 PF07690.11 KKK25682.1 - 4.3e-18 65.1 10.4 5.1e-18 64.8 7.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK25682.1 - 0.029 12.9 11.5 0.04 12.4 7.9 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter UQ_con PF00179.21 KKK25684.1 - 2.4e-41 140.4 0.0 3.6e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK25684.1 - 0.00027 20.6 0.0 0.00042 20.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KKK25684.1 - 0.12 12.2 1.9 0.19 11.6 1.1 1.7 1 1 1 2 2 2 0 RWD domain HhH-GPD PF00730.20 KKK25686.1 - 1.6e-19 70.1 0.0 6.3e-19 68.2 0.0 1.9 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KKK25686.1 - 2.1e-06 27.0 0.0 4.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Adaptin_N PF01602.15 KKK25687.1 - 2.7e-106 356.0 0.0 4.1e-106 355.3 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KKK25687.1 - 4.2e-10 39.7 2.4 0.0076 16.5 0.0 5.2 4 1 0 5 5 5 3 HEAT repeats HEAT PF02985.17 KKK25687.1 - 2.7e-08 33.1 0.0 0.043 13.9 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 KKK25687.1 - 0.0019 17.9 3.2 1.4 8.8 0.1 5.5 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KKK25687.1 - 0.021 14.1 0.6 8.6 5.6 0.0 3.5 3 1 1 4 4 4 0 CLASP N terminal Cnd1 PF12717.2 KKK25687.1 - 0.025 14.4 0.1 6.7 6.5 0.0 3.3 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 KKK25687.1 - 0.026 14.4 0.4 2.1 8.4 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion SDA1 PF05285.7 KKK25687.1 - 3 7.0 15.6 1.4 8.1 7.6 2.0 2 0 0 2 2 2 0 SDA1 Metallophos PF00149.23 KKK25688.1 - 2.6e-41 141.2 0.4 3.3e-41 140.8 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IF-2B PF01008.12 KKK25689.1 - 6.4e-48 163.1 0.0 1.7e-47 161.7 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Nuf2 PF03800.9 KKK25690.1 - 3.3e-45 153.6 0.7 1.2e-44 151.8 0.0 2.3 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 KKK25690.1 - 0.27 10.3 9.4 1.5 7.9 3.6 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein STAT_alpha PF01017.15 KKK25690.1 - 5.8 6.5 31.6 0.2 11.3 7.5 2.5 2 0 0 2 2 2 0 STAT protein, all-alpha domain Bacillus_HBL PF05791.6 KKK25690.1 - 6.8 6.0 21.6 2 7.7 0.6 3.5 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.7 KKK25690.1 - 7.7 6.2 34.9 2 8.1 7.6 3.4 1 1 2 3 3 3 0 Laminin Domain II Fungal_trans PF04082.13 KKK25692.1 - 3.5e-12 45.7 0.3 5.9e-12 45.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25692.1 - 2.8e-06 27.1 8.8 4.9e-06 26.3 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Smg4_UPF3 PF03467.10 KKK25693.1 - 1.9e-27 96.4 0.2 5.1e-27 94.9 0.0 1.8 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 KKK25693.1 - 5e-09 35.6 0.3 3.5e-07 29.7 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK25693.1 - 2e-06 27.6 0.0 1.2e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK25693.1 - 1.3e-05 24.9 0.0 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK25693.1 - 0.0084 15.8 0.1 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Wyosine_form PF08608.7 KKK25694.1 - 6.7e-24 83.7 0.0 1.7e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 KKK25694.1 - 1e-15 58.2 0.0 2.8e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 KKK25694.1 - 2.7e-09 37.1 0.8 3.6e-07 30.2 0.5 2.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 KKK25694.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Sugar_tr PF00083.19 KKK25695.1 - 1.1e-57 195.6 16.0 1.2e-57 195.5 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25695.1 - 1.6e-15 56.7 31.9 9e-12 44.3 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily C_GCAxxG_C_C PF09719.5 KKK25695.1 - 0.1 12.3 0.1 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Metallophos PF00149.23 KKK25696.1 - 8.3e-37 126.5 0.1 4.4e-32 111.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase NUDIX PF00293.23 KKK25697.1 - 6.1e-14 51.8 1.0 1.8e-13 50.3 0.7 1.7 1 1 0 1 1 1 1 NUDIX domain WD40 PF00400.27 KKK25698.1 - 5.6e-15 54.5 0.3 0.0011 18.7 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KKK25698.1 - 0.006 14.7 0.1 0.11 10.6 0.0 2.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 APH PF01636.18 KKK25699.1 - 3.4e-09 36.8 0.0 8.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KKK25699.1 - 0.0097 14.5 0.0 0.018 13.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Myb_DNA-binding PF00249.26 KKK25701.1 - 1e-23 83.0 1.3 2.4e-13 49.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK25701.1 - 4.4e-20 71.5 5.1 4.2e-15 55.5 0.0 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KKK25701.1 - 0.022 14.8 1.3 0.052 13.6 0.1 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_38 PF13936.1 KKK25701.1 - 0.027 14.0 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2774 PF11242.3 KKK25701.1 - 0.027 14.4 0.0 0.062 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) HTH_23 PF13384.1 KKK25701.1 - 0.15 11.7 0.1 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain ATE_C PF04377.10 KKK25707.1 - 6.6e-47 158.7 3.3 1.1e-46 158.0 2.3 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KKK25707.1 - 1.8e-15 56.4 0.9 1.8e-15 56.4 0.6 2.2 3 0 0 3 3 3 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KKK25707.1 - 7.6e-05 22.6 0.3 0.00015 21.7 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kelch_2 PF07646.10 KKK25707.1 - 0.0036 17.0 0.2 0.19 11.5 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Nop14 PF04147.7 KKK25708.1 - 0.5 8.2 3.4 0.73 7.6 2.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cytochrom_C PF00034.16 KKK25709.1 - 2.2e-10 41.2 0.0 4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KKK25709.1 - 1.4e-07 31.5 2.9 2.4e-06 27.6 2.0 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KKK25709.1 - 5.6e-05 22.6 0.1 0.00013 21.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.4 KKK25709.1 - 0.0096 15.2 0.1 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Photosystem P840 reaction-centre cytochrome c-551 Haem_bd PF14376.1 KKK25709.1 - 0.037 13.7 0.1 0.072 12.7 0.1 1.5 2 0 0 2 2 2 0 Haem-binding domain RNase_PH PF01138.16 KKK25710.1 - 3.5e-12 46.7 0.0 8e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KKK25710.1 - 0.029 14.2 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Baculo_PEP_C PF04513.7 KKK25711.1 - 0.081 12.7 2.7 0.27 11.0 0.1 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_A_bac PF01000.21 KKK25712.1 - 5.3e-32 110.2 0.0 8.4e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KKK25712.1 - 2.6e-13 48.8 0.0 3.4e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NUDIX PF00293.23 KKK25713.1 - 9.1e-16 57.7 0.1 1.1e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain RRM_1 PF00076.17 KKK25714.1 - 4.2e-08 32.6 0.0 1.2e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK25714.1 - 4e-06 26.4 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 KKK25714.1 - 1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IBN_N PF03810.14 KKK25715.1 - 1.4e-17 63.4 4.1 4.2e-14 52.2 0.0 5.0 5 0 0 5 5 5 2 Importin-beta N-terminal domain Cse1 PF08506.5 KKK25715.1 - 1.8e-07 30.0 0.0 4.5e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 KKK25715.1 - 8.3e-05 22.5 1.6 0.019 14.8 0.0 3.7 3 1 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 KKK25715.1 - 8.4e-05 22.7 2.5 0.072 13.3 0.0 3.6 3 1 0 3 3 3 2 HEAT repeats DUF2435 PF10363.4 KKK25715.1 - 0.003 17.4 0.5 0.04 13.8 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Terpene_synth_C PF03936.11 KKK25715.1 - 0.023 13.9 0.2 0.097 11.8 0.0 2.1 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain DSHCT PF08148.7 KKK25716.1 - 6.8e-62 207.8 0.7 1.5e-61 206.8 0.5 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KKK25716.1 - 2.3e-20 72.7 0.0 4.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK25716.1 - 9.7e-07 28.5 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK25716.1 - 0.0059 16.4 0.1 0.12 12.1 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2415 PF10313.4 KKK25717.1 - 1.3e-15 56.8 0.1 4.8e-15 54.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KKK25717.1 - 0.064 13.1 3.1 3.7 7.5 0.2 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat CAF-1_p150 PF11600.3 KKK25717.1 - 0.16 11.3 3.1 0.27 10.5 2.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HSP70 PF00012.15 KKK25718.1 - 1.7e-266 884.9 18.3 1.9e-266 884.7 12.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KKK25718.1 - 5.6e-16 58.0 8.2 1.8e-14 53.0 1.4 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 KKK25718.1 - 0.001 18.6 0.0 0.0031 17.1 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KKK25718.1 - 0.017 14.9 12.0 0.19 11.6 0.1 4.6 3 3 0 3 3 3 0 Cell division protein FtsA Hormone_1 PF00103.15 KKK25718.1 - 0.28 10.5 4.1 0.42 9.9 0.3 2.5 2 1 0 2 2 2 0 Somatotropin hormone family DUF4363 PF14276.1 KKK25718.1 - 0.31 10.7 3.0 0.68 9.6 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Hydantoinase_A PF01968.13 KKK25718.1 - 1.5 7.8 7.5 2.2 7.2 0.1 3.3 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase DUF603 PF04645.7 KKK25718.1 - 5.9 6.7 10.2 9.4 6.1 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF603 SKG6 PF08693.5 KKK25719.1 - 0.14 11.5 0.5 0.27 10.5 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HA2 PF04408.18 KKK25720.1 - 1.9e-20 72.7 0.1 5.7e-20 71.2 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK25720.1 - 1.3e-12 47.4 1.5 2e-12 46.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK25720.1 - 4.9e-11 42.4 0.0 9.8e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KKK25720.1 - 1.3e-07 31.4 0.0 4.9e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KKK25720.1 - 2.4e-06 27.7 0.0 8.3e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF3554 PF12074.3 KKK25721.1 - 2.4e-115 385.5 3.5 2.4e-115 385.5 2.4 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 KKK25721.1 - 8.7e-58 194.2 9.9 2.2e-57 192.9 6.8 1.8 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_2 PF13646.1 KKK25721.1 - 2e-36 124.1 38.0 1.6e-08 34.6 0.9 14.6 5 3 9 14 14 14 10 HEAT repeats HEAT PF02985.17 KKK25721.1 - 1.4e-33 111.8 27.2 0.14 12.2 0.0 20.9 22 0 0 22 22 22 9 HEAT repeat HEAT_EZ PF13513.1 KKK25721.1 - 5.3e-24 84.0 53.3 0.013 15.9 0.1 21.6 18 5 8 26 26 26 9 HEAT-like repeat Cnd1 PF12717.2 KKK25721.1 - 8.9e-11 41.9 4.6 0.026 14.3 0.2 7.6 6 2 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 KKK25721.1 - 1.4e-09 38.1 6.2 0.12 12.2 0.0 6.7 5 1 1 6 6 6 3 Parkin co-regulated protein Vac14_Fab1_bd PF12755.2 KKK25721.1 - 3.1e-09 37.0 0.0 2.2 8.7 0.0 8.4 7 2 3 10 10 10 1 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 KKK25721.1 - 3.3e-07 30.2 0.5 1 9.3 0.0 6.1 5 0 0 5 5 5 2 Rix1 complex component involved in 60S ribosome maturation Cnd3 PF12719.2 KKK25721.1 - 0.0036 16.3 6.0 0.35 9.8 0.0 4.8 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain WD40 PF00400.27 KKK25722.1 - 1.2e-15 56.7 4.3 5.2e-07 29.3 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat EMP70 PF02990.11 KKK25722.1 - 0.16 10.4 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Sugar_tr PF00083.19 KKK25753.1 - 2.2e-25 89.1 16.8 3e-25 88.7 11.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25753.1 - 1e-09 37.6 18.5 1.5e-09 37.0 12.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily GtrA PF04138.9 KKK25753.1 - 0.022 14.7 1.8 0.58 10.1 0.0 2.6 2 1 0 2 2 2 0 GtrA-like protein YbgT_YccB PF08173.6 KKK25753.1 - 0.89 9.4 0.0 0.89 9.4 0.0 3.0 4 0 0 4 4 4 0 Membrane bound YbgT-like protein Acetate_kinase PF00871.12 KKK25754.1 - 2.3e-87 293.0 0.0 2.8e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Cyclin PF08613.6 KKK25755.1 - 1.8e-14 54.4 0.1 2.5e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KKK25755.1 - 0.0009 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain MARVEL PF01284.18 KKK25756.1 - 9.5e-23 80.6 15.4 1.1e-22 80.4 10.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF1385 PF07136.6 KKK25756.1 - 0.085 11.9 0.6 0.11 11.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) DUF2304 PF10066.4 KKK25756.1 - 2.3 8.0 8.4 0.64 9.8 3.2 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Cys_Met_Meta_PP PF01053.15 KKK25757.1 - 4.6e-127 423.4 0.0 5.2e-127 423.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KKK25757.1 - 1.9e-13 50.2 1.4 1.9e-13 50.2 1.0 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KKK25757.1 - 1.1e-08 34.4 0.2 1.8e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KKK25757.1 - 1.9e-07 30.1 0.4 5.1e-07 28.7 0.3 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KKK25757.1 - 8.7e-07 28.3 0.0 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KKK25757.1 - 0.00021 19.7 0.0 0.00025 19.4 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KKK25757.1 - 0.025 13.2 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 KKK25757.1 - 0.065 11.6 0.0 0.094 11.1 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Ribosomal_L7Ae PF01248.21 KKK25785.1 - 1.5e-25 88.5 0.0 1.7e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Sua5_yciO_yrdC PF01300.13 KKK25787.1 - 4.3e-55 185.7 0.0 1.1e-54 184.4 0.0 1.7 1 0 0 1 1 1 1 Telomere recombination DUF3441 PF11923.3 KKK25787.1 - 2.4e-39 133.4 0.1 2.4e-39 133.4 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 KKK25787.1 - 4.1e-27 94.8 15.0 2.4e-22 79.1 0.1 3.3 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) SUA5 PF03481.8 KKK25787.1 - 1.6e-26 92.8 0.1 1.6e-25 89.6 0.0 2.7 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding DUF814 PF05670.8 KKK25787.1 - 5.7e-16 58.1 0.0 1.5e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Clat_adaptor_s PF01217.15 KKK25787.1 - 4e-10 39.5 0.0 1.7e-08 34.2 0.1 2.8 3 0 0 3 3 3 1 Clathrin adaptor complex small chain Ribosomal_L16 PF00252.13 KKK25788.1 - 2.7e-32 111.3 0.2 3.4e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PALP PF00291.20 KKK25789.1 - 2.2e-09 37.0 0.0 2.8e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IlvN PF07991.7 KKK25790.1 - 6.5e-46 155.7 0.0 9.3e-46 155.2 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KKK25790.1 - 5.8e-45 152.7 0.0 1.1e-44 151.8 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KKK25790.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KKK25790.1 - 0.083 13.3 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Isochorismatase PF00857.15 KKK25791.1 - 3.4e-21 75.9 0.0 4.8e-20 72.1 0.0 2.7 1 1 1 2 2 2 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 KKK25791.1 - 1.6e-20 73.7 0.0 2.8e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_3 PF14497.1 KKK25791.1 - 1.2e-06 28.8 0.0 3.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KKK25791.1 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK25791.1 - 6.2e-05 22.8 0.0 0.00016 21.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ECH PF00378.15 KKK25792.1 - 4.7e-27 94.6 0.7 1.1e-26 93.5 0.1 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family Sigma70_ner PF04546.8 KKK25792.1 - 0.084 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.1 KKK25792.1 - 0.84 9.8 3.5 1.1 9.4 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Glyco_hydro_43 PF04616.9 KKK25793.1 - 1.9e-33 115.7 0.0 2.6e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KKK25793.1 - 0.091 12.1 0.1 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain Glyco_transf_90 PF05686.7 KKK25794.1 - 2e-28 99.2 0.0 3.2e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KKK25794.1 - 8.6e-05 22.7 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kinesin PF00225.18 KKK25795.1 - 4.8e-112 373.9 0.0 7.3e-112 373.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KKK25795.1 - 4.3e-43 146.3 0.1 1e-42 145.1 0.1 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KKK25795.1 - 1.1e-08 35.2 0.0 3.4e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 PH domain KIF1B PF12423.3 KKK25795.1 - 6.9e-08 32.3 0.3 2e-07 30.9 0.2 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KKK25795.1 - 3.3e-05 23.8 0.8 0.00074 19.5 0.0 3.5 4 0 0 4 4 4 1 FHA domain Phosphodiest PF01663.17 KKK25798.1 - 1.1e-83 281.5 0.1 1.6e-83 281.0 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KKK25798.1 - 0.0018 17.5 0.1 1.3 8.1 0.0 2.2 1 1 1 2 2 2 2 Sulfatase PglZ PF08665.7 KKK25798.1 - 0.0085 15.7 0.1 0.67 9.5 0.0 2.8 3 0 0 3 3 3 1 PglZ domain DUF229 PF02995.12 KKK25798.1 - 0.16 10.3 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) BCS1_N PF08740.6 KKK25799.1 - 5.5e-56 189.1 0.1 5.5e-56 189.1 0.0 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KKK25799.1 - 1.7e-15 57.3 0.0 3.8e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KKK25799.1 - 0.0022 18.8 0.1 0.012 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KKK25799.1 - 0.01 14.7 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KKK25799.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KKK25799.1 - 0.022 14.5 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KKK25799.1 - 0.033 14.4 0.0 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KKK25799.1 - 0.038 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KKK25799.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 KKK25799.1 - 0.064 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 KKK25799.1 - 1.4 8.4 7.9 28 4.1 5.5 2.2 1 1 0 1 1 1 0 AAA domain Actin PF00022.14 KKK25800.1 - 3.4e-22 78.4 0.0 8.6e-19 67.2 0.0 3.3 2 1 0 2 2 2 2 Actin XPG_I PF00867.13 KKK25801.1 - 2.1e-22 78.9 0.1 6.7e-22 77.3 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KKK25801.1 - 1.9e-07 31.2 0.0 4.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain DUF1961 PF09224.6 KKK25801.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) CFEM PF05730.6 KKK25802.1 - 0.00022 20.9 5.5 0.00022 20.9 3.8 3.4 3 0 0 3 3 3 1 CFEM domain Tme5_EGF_like PF09064.5 KKK25802.1 - 0.66 9.6 5.1 0.37 10.4 1.3 2.3 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like MFS_1 PF07690.11 KKK25804.1 - 4.3e-21 75.0 58.2 9.7e-20 70.5 40.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK25804.1 - 1.1e-10 40.7 15.3 1.1e-10 40.7 10.6 3.1 3 1 1 4 4 4 1 Sugar (and other) transporter MLANA PF14991.1 KKK25805.1 - 0.058 13.4 2.8 0.91 9.5 0.0 2.8 2 1 0 2 2 2 0 Protein melan-A ADH_zinc_N PF00107.21 KKK25807.1 - 1.6e-18 66.5 0.0 2.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK25807.1 - 4.8e-12 46.8 0.0 9.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.13 KKK25808.1 - 1.8e-06 27.7 9.9 1.8e-06 27.7 6.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK25808.1 - 0.004 16.0 0.2 0.0097 14.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain LZ_Tnp_IS66 PF13007.2 KKK25808.1 - 0.017 15.7 1.3 0.037 14.6 0.9 1.6 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain HSBP1 PF06825.7 KKK25808.1 - 0.063 12.8 1.2 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 N_NLPC_P60 PF12912.2 KKK25808.1 - 0.097 12.7 0.6 0.19 11.8 0.4 1.4 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term p450 PF00067.17 KKK25809.1 - 4.5e-39 134.2 0.0 6.2e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldose_epim PF01263.15 KKK25810.1 - 9.9e-50 169.3 0.0 1.3e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Fer2_4 PF13510.1 KKK25810.1 - 0.0046 16.7 0.1 0.78 9.5 0.0 2.4 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain AT_hook PF02178.14 KKK25811.1 - 0.061 13.0 21.7 0.59 9.9 4.2 3.1 2 0 0 2 2 2 0 AT hook motif adh_short_C2 PF13561.1 KKK25813.1 - 4.4e-29 101.9 0.0 5.8e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK25813.1 - 7.5e-27 94.2 0.0 2.4e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK25813.1 - 1.3e-07 31.4 0.0 3.7e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK25813.1 - 3e-05 23.5 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CENP-K PF11802.3 KKK25813.1 - 0.049 12.8 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF1776 PF08643.5 KKK25813.1 - 0.068 12.2 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) C2 PF00168.25 KKK25820.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 C2 domain DDHD PF02862.12 KKK25821.1 - 1.5e-46 159.0 1.1 1.8e-27 96.6 0.0 3.1 2 2 1 3 3 3 2 DDHD domain Abhydrolase_5 PF12695.2 KKK25821.1 - 0.023 14.4 0.0 0.066 12.9 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3140 PF11338.3 KKK25822.1 - 0.0077 16.3 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) BCDHK_Adom3 PF10436.4 KKK25822.1 - 0.027 13.9 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase ADH_zinc_N PF00107.21 KKK25824.1 - 3.1e-27 94.6 0.2 4.9e-27 94.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK25824.1 - 3.4e-12 46.1 1.3 6.9e-12 45.0 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KKK25824.1 - 1.7e-06 28.9 0.0 3.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Arf PF00025.16 KKK25825.1 - 8.8e-74 246.4 0.0 1.1e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KKK25825.1 - 1.9e-12 46.7 0.0 2.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KKK25825.1 - 3e-10 39.7 0.0 3.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KKK25825.1 - 6.4e-10 38.2 0.4 4.5e-06 25.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KKK25825.1 - 4.4e-09 35.8 0.0 5.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK25825.1 - 4.3e-08 33.6 0.0 5.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK25825.1 - 5.5e-06 26.3 0.0 7.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK25825.1 - 3.9e-05 23.1 0.0 0.0057 16.1 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KKK25825.1 - 0.023 13.9 0.4 0.087 12.1 0.3 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Paf1 PF03985.8 KKK25826.1 - 7.7e-40 136.9 0.8 1.2e-27 96.7 0.0 3.1 2 1 0 2 2 2 2 Paf1 Actin PF00022.14 KKK25826.1 - 8.1e-29 100.2 0.0 4.3e-17 61.6 0.0 2.4 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KKK25826.1 - 0.00012 20.7 0.1 0.13 10.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2114 PF09887.4 KKK25826.1 - 0.27 9.5 0.0 0.36 9.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) DUF3419 PF11899.3 KKK25827.1 - 8.4e-155 515.1 0.1 1.2e-154 514.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KKK25827.1 - 9.4e-13 48.1 0.0 7.5e-11 42.0 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK25827.1 - 7.4e-09 35.9 0.0 2.4e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK25827.1 - 2.5e-08 34.4 0.0 1.2e-07 32.2 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK25827.1 - 9.1e-08 31.8 0.0 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK25827.1 - 1.6e-06 28.1 0.0 1.7e-05 24.8 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK25827.1 - 5.9e-06 26.6 0.0 0.00052 20.4 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK25827.1 - 8.1e-06 25.1 0.0 3.4e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KKK25827.1 - 3.8e-05 23.9 0.0 0.00022 21.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 KKK25827.1 - 0.00016 21.3 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KKK25827.1 - 0.0043 16.7 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KKK25827.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Glyco_hydro_17 PF00332.13 KKK25864.1 - 7.9e-10 38.2 3.9 8.2e-06 25.0 0.7 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 rRNA_proc-arch PF13234.1 KKK25865.1 - 1.7e-98 329.1 0.0 3.7e-98 327.9 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KKK25865.1 - 1.2e-64 216.8 3.3 1.2e-64 216.8 2.3 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 KKK25865.1 - 2.5e-21 75.9 0.2 1.2e-20 73.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK25865.1 - 8.3e-07 28.7 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KKK25865.1 - 0.0093 14.8 0.0 0.04 12.8 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein Prp19 PF08606.6 KKK25865.1 - 0.028 14.1 0.6 0.82 9.4 0.2 2.7 2 0 0 2 2 2 0 Prp19/Pso4-like ResIII PF04851.10 KKK25865.1 - 0.033 14.0 0.0 0.29 10.9 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit COX7C PF02935.11 KKK25866.1 - 1e-11 44.4 2.1 1e-11 44.4 1.5 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.7 KKK25867.1 - 0 1074.0 0.0 0 1072.9 0.0 1.5 1 1 0 1 1 1 1 IKI3 family BTAD PF03704.12 KKK25867.1 - 0.029 14.6 1.5 0.059 13.6 1.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Pyr_redox_dim PF02852.17 KKK25868.1 - 1.6e-34 118.2 0.1 1.9e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DSPc PF00782.15 KKK25869.1 - 2.8e-25 88.4 0.0 3.7e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KKK25869.1 - 0.0003 20.2 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KKK25869.1 - 0.016 14.1 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 KKK25869.1 - 0.045 14.0 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family IBR PF01485.16 KKK25869.1 - 0.071 12.9 2.2 0.56 10.1 0.2 2.4 2 0 0 2 2 2 0 IBR domain PTPlike_phytase PF14566.1 KKK25869.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate TFIID_20kDa PF03847.8 KKK25870.1 - 1.4e-21 76.5 0.0 2.9e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 KKK25870.1 - 0.016 15.2 0.0 0.047 13.8 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DASH_Spc34 PF08657.5 KKK25871.1 - 3.1e-67 226.9 9.4 6.7e-66 222.6 6.5 2.1 1 1 0 1 1 1 1 DASH complex subunit Spc34 REV PF00424.13 KKK25871.1 - 0.0019 18.0 0.1 0.024 14.5 0.2 2.3 2 0 0 2 2 2 1 REV protein (anti-repression trans-activator protein) DUF3866 PF12982.2 KKK25871.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) IncA PF04156.9 KKK25871.1 - 0.19 11.3 3.3 0.14 11.7 1.1 1.5 1 1 0 1 1 1 0 IncA protein Rpn3_C PF08375.6 KKK25872.1 - 1.3e-24 86.3 0.4 5.4e-24 84.3 0.2 2.1 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KKK25872.1 - 2.1e-19 69.7 0.9 1.2e-18 67.3 0.0 2.5 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 KKK25872.1 - 0.0019 17.9 1.0 0.02 14.6 0.2 2.5 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 polyprenyl_synt PF00348.12 KKK25873.1 - 4.2e-50 170.0 0.0 4.2e-48 163.4 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase DUF2404 PF10296.4 KKK25873.1 - 5.5e-30 103.3 0.0 1.2e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) UPF0449 PF15136.1 KKK25873.1 - 0.076 13.2 0.1 20 5.4 0.0 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 HEPPP_synt_1 PF07307.6 KKK25873.1 - 0.16 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 ANTH PF07651.11 KKK25874.1 - 4.3e-73 245.4 0.0 4.3e-73 245.4 0.0 3.3 3 1 0 4 4 4 1 ANTH domain I_LWEQ PF01608.12 KKK25874.1 - 1.8e-64 216.3 9.2 1.8e-64 216.3 6.4 5.7 3 2 4 7 7 7 1 I/LWEQ domain DEAD PF00270.24 KKK25892.1 - 3.2e-36 124.3 0.0 1.3e-35 122.3 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KKK25892.1 - 2e-20 72.1 0.0 3.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KKK25892.1 - 1.5e-18 66.4 0.0 3.3e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK25892.1 - 0.0044 16.8 0.2 0.022 14.6 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KKK25892.1 - 0.028 14.5 0.0 1.1 9.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.16 KKK25892.1 - 0.089 12.0 3.1 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF1289 PF06945.8 KKK25892.1 - 2.4 7.6 5.7 0.54 9.7 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) CTP_transf_1 PF01148.15 KKK25893.1 - 3.2e-14 53.2 8.6 2.2e-12 47.1 4.0 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family DUF3984 PF13136.1 KKK25893.1 - 8.5 5.4 12.5 12 5.0 7.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) GFO_IDH_MocA PF01408.17 KKK25915.1 - 3.4e-11 43.6 0.0 9.6e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SRP72 PF08492.7 KKK25916.1 - 4.6e-17 62.1 3.6 4.6e-17 62.1 2.5 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 KKK25916.1 - 6.4e-07 29.6 13.0 0.1 12.9 0.0 6.3 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KKK25916.1 - 3.2e-05 23.7 3.9 0.12 12.3 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK25916.1 - 0.00012 21.7 2.3 18 5.5 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK25916.1 - 0.00041 20.7 14.1 3.3 8.5 0.0 8.0 8 2 3 11 11 10 1 Tetratricopeptide repeat TPR_4 PF07721.9 KKK25916.1 - 0.0027 17.9 2.6 12 6.6 0.0 5.4 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK25916.1 - 0.0057 16.2 0.5 21 4.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat SPO22 PF08631.5 KKK25916.1 - 0.012 14.7 0.5 0.033 13.2 0.1 1.9 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like BTAD PF03704.12 KKK25916.1 - 0.054 13.7 0.3 0.054 13.7 0.2 3.5 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 KKK25916.1 - 0.057 13.5 1.9 0.24 11.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KKK25916.1 - 0.087 12.9 12.4 8.2 6.6 0.1 5.0 3 1 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KKK25916.1 - 0.13 12.2 4.5 35 4.6 0.0 5.3 7 0 0 7 7 6 0 PPR repeat Glyco_hydro_31 PF01055.21 KKK25917.1 - 2.3e-164 547.4 1.6 3.3e-164 546.9 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Rotavirus_VP7 PF05868.6 KKK25917.1 - 0.0015 17.7 0.2 0.0028 16.8 0.1 1.3 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 HNH_2 PF13391.1 KKK25918.1 - 5.7e-05 22.8 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Fringe PF02434.11 KKK25919.1 - 2.7e-09 36.6 0.0 1e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.7 KKK25919.1 - 9e-07 28.3 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fungal_trans PF04082.13 KKK25920.1 - 1.1e-21 76.9 0.0 2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25920.1 - 5e-09 35.9 11.6 1.2e-08 34.6 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain vWA-TerF-like PF10138.4 KKK25921.1 - 0.00016 21.6 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus DPPIV_N PF00930.16 KKK25922.1 - 2.9e-114 381.3 0.0 3.7e-114 381.0 0.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KKK25922.1 - 3.3e-52 176.7 3.3 4.8e-52 176.2 2.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK25922.1 - 2.6e-09 36.9 0.0 5.2e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK25922.1 - 2.6e-06 27.4 0.1 2.7e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KKK25922.1 - 0.00012 21.5 0.2 0.00033 20.1 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 KKK25922.1 - 0.00013 21.5 3.7 0.00089 18.7 0.9 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.8 KKK25922.1 - 0.00065 18.1 0.0 0.25 9.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.13 KKK25922.1 - 0.039 13.2 0.3 0.14 11.4 0.2 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KKK25922.1 - 0.045 13.1 0.2 2.1 7.7 0.1 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3395 PF11875.3 KKK25930.1 - 6.3e-47 158.9 0.2 6.3e-47 158.9 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) Nucleoplasmin PF03066.10 KKK25930.1 - 0.0035 16.8 10.6 0.029 13.8 1.7 2.3 2 0 0 2 2 2 2 Nucleoplasmin CDC45 PF02724.9 KKK25930.1 - 0.17 9.9 6.5 0.024 12.6 0.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Daxx PF03344.10 KKK25930.1 - 5.9 5.2 16.0 1.1 7.6 3.2 2.2 2 0 0 2 2 2 0 Daxx Family Sigma70_ner PF04546.8 KKK25930.1 - 6 6.4 17.9 0.043 13.4 1.7 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region Nop14 PF04147.7 KKK25930.1 - 7.3 4.3 15.8 0.17 9.8 3.3 2.1 2 0 0 2 2 2 0 Nop14-like family FAM176 PF14851.1 KKK25930.1 - 7.8 6.1 11.5 13 5.4 2.8 2.4 2 0 0 2 2 2 0 FAM176 family SKIP_SNW PF02731.10 KKK25931.1 - 2.5e-68 228.5 4.8 2.5e-68 228.5 3.4 2.5 2 0 0 2 2 2 1 SKIP/SNW domain FAM60A PF15396.1 KKK25931.1 - 5.1 6.7 10.3 12 5.6 7.1 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Ras PF00071.17 KKK25932.1 - 9.8e-36 122.5 0.0 1.1e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK25932.1 - 4.7e-09 36.7 0.0 1.2e-08 35.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein DUF4055 PF13264.1 KKK25932.1 - 0.16 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) NST1 PF13945.1 KKK25933.1 - 1.2e-71 240.7 0.9 1.2e-71 240.7 0.7 4.5 2 2 2 4 4 4 1 Salt tolerance down-regulator ketoacyl-synt PF00109.21 KKK25964.1 - 2.9e-68 230.1 0.0 6e-68 229.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KKK25964.1 - 4.2e-62 209.0 0.4 9.5e-62 207.8 0.3 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KKK25964.1 - 1.9e-57 195.0 0.4 3.8e-56 190.7 0.0 2.7 2 1 1 3 3 3 1 Acyl transferase domain PS-DH PF14765.1 KKK25964.1 - 9.7e-55 185.8 0.0 1.6e-54 185.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KKK25964.1 - 7.6e-47 159.3 0.2 2.2e-46 157.8 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KKK25964.1 - 9.9e-40 135.1 0.0 2.6e-39 133.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KKK25964.1 - 8.3e-07 28.6 0.0 2.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KKK25964.1 - 1.5e-06 27.9 0.0 4.8e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK25964.1 - 2.4e-06 27.3 0.0 6.5e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK25964.1 - 0.0001 22.7 0.0 0.00032 21.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KKK25964.1 - 0.00066 18.7 0.3 0.0012 17.8 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 KKK25964.1 - 0.0015 18.7 0.1 0.009 16.2 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.7 KKK25964.1 - 0.0021 17.8 0.0 0.0066 16.2 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KKK25964.1 - 0.0064 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KKK25964.1 - 0.017 15.5 0.0 0.059 13.8 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain YflT PF11181.3 KKK25964.1 - 0.12 12.4 0.0 0.71 10.0 0.0 2.3 2 0 0 2 2 2 0 Heat induced stress protein YflT ABC2_membrane PF01061.19 KKK25965.1 - 1e-90 302.5 45.0 6.3e-49 166.0 12.6 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KKK25965.1 - 6.9e-39 133.2 0.0 2e-18 67.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KKK25965.1 - 1.2e-29 102.0 5.2 4.5e-28 96.9 0.0 3.1 3 0 0 3 3 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KKK25965.1 - 1.2e-06 27.8 38.2 0.00041 19.4 12.3 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KKK25965.1 - 2.2e-06 27.1 0.1 0.0049 16.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK25965.1 - 4.4e-06 26.8 0.0 0.074 13.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK25965.1 - 6.4e-05 23.7 0.0 0.61 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 KKK25965.1 - 8.7e-05 22.5 0.2 0.00023 21.2 0.2 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 KKK25965.1 - 0.00026 21.0 0.3 0.1 12.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KKK25965.1 - 0.00047 20.0 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KKK25965.1 - 0.00085 19.3 0.9 0.38 10.6 0.3 2.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 KKK25965.1 - 0.00089 18.7 0.8 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KKK25965.1 - 0.0012 18.3 1.4 0.4 10.0 0.3 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KKK25965.1 - 0.0015 18.0 0.5 0.078 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KKK25965.1 - 0.0019 17.3 0.0 0.018 14.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KKK25965.1 - 0.0022 18.2 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK25965.1 - 0.0048 16.6 0.1 2.1 8.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KKK25965.1 - 0.005 16.5 0.8 3.1 7.4 0.1 2.4 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 KKK25965.1 - 0.019 14.4 0.3 0.73 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 KKK25965.1 - 0.03 14.2 0.0 2.2 8.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KKK25965.1 - 0.045 13.9 0.0 8.9 6.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KKK25965.1 - 0.047 13.3 0.0 5.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 KKK25965.1 - 0.064 12.8 0.5 5.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KKK25965.1 - 0.13 12.0 0.1 21 4.7 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KKK25965.1 - 0.13 12.1 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KKK25965.1 - 0.13 12.7 0.0 4.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein DUF1212 PF06738.7 KKK25966.1 - 3.4e-56 189.7 16.4 1.5e-50 171.3 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KKK25966.1 - 5.4e-28 97.5 10.4 5.4e-28 97.5 7.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) Lipase_2 PF01674.13 KKK25967.1 - 2.6e-08 33.4 0.1 6.9e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_6 PF12697.2 KKK25967.1 - 8.8e-08 32.2 0.4 1.7e-07 31.4 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK25967.1 - 1.7e-05 24.5 0.1 3.2e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 KKK25967.1 - 0.004 16.0 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF900 PF05990.7 KKK25967.1 - 0.016 14.5 0.0 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 KKK25967.1 - 0.021 14.3 0.0 0.054 13.0 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.11 KKK25967.1 - 0.04 13.3 0.0 0.15 11.5 0.0 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF676 PF05057.9 KKK25967.1 - 0.066 12.4 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) MFS_1 PF07690.11 KKK25968.1 - 4.1e-16 58.6 49.1 3.1e-11 42.6 23.0 2.4 2 1 0 3 3 3 2 Major Facilitator Superfamily GFA PF04828.9 KKK25969.1 - 1.1e-20 73.3 1.2 1.5e-20 72.9 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-Dof PF02701.10 KKK25969.1 - 0.095 12.6 2.2 4.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Dof domain, zinc finger zf-CSL PF05207.8 KKK25969.1 - 0.91 9.0 6.6 0.33 10.4 0.6 2.2 2 0 0 2 2 2 0 CSL zinc finger Aldolase_II PF00596.16 KKK25970.1 - 1.5e-48 164.8 0.1 1.9e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain S-methyl_trans PF02574.11 KKK25971.1 - 3.1e-33 115.3 0.0 5.7e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Homocysteine S-methyltransferase LysM PF01476.15 KKK25971.1 - 1.6e-24 85.4 7.9 4.8e-09 35.9 0.1 5.3 5 0 0 5 5 5 4 LysM domain Glyco_hydro_18 PF00704.23 KKK25972.1 - 1.1e-76 258.5 5.3 2.3e-76 257.5 3.7 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KKK25972.1 - 1.7e-07 31.1 9.4 1.7e-07 31.1 6.5 5.6 5 1 0 5 5 5 2 Chitin recognition protein UPF0113 PF03657.8 KKK25974.1 - 1e-06 28.5 0.0 1.6e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 KKK25974.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 PUA domain NRDE PF05742.7 KKK25975.1 - 4.2e-37 127.9 0.0 1.3e-36 126.3 0.0 1.6 1 1 0 1 1 1 1 NRDE protein Fungal_trans_2 PF11951.3 KKK25976.1 - 5.3e-07 28.5 0.0 1.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25976.1 - 2e-05 24.4 12.6 2e-05 24.4 8.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribophorin_II PF05817.9 KKK25977.1 - 4.2e-20 71.5 0.0 5.5e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Ribosomal_60s PF00428.14 KKK25979.1 - 1.8 9.0 8.2 0.14 12.5 1.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF605 PF04652.11 KKK25979.1 - 7 5.9 12.4 1.2e+02 1.8 10.0 1.8 2 1 0 2 2 2 0 Vta1 like His_Phos_2 PF00328.17 KKK25980.1 - 1.1e-60 205.8 0.0 1.2e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Beta_protein PF14350.1 KKK25980.1 - 0.081 12.0 0.0 0.32 10.1 0.0 1.9 1 1 0 2 2 2 0 Beta protein HAMP PF00672.20 KKK25982.1 - 1.1e-49 166.4 16.6 8e-10 38.7 0.4 6.9 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 KKK25982.1 - 4.9e-31 106.7 0.1 1.9e-30 104.8 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK25982.1 - 2.5e-28 98.3 0.3 1.5e-26 92.5 0.3 3.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KKK25982.1 - 4.5e-16 58.6 0.1 4.5e-16 58.6 0.1 4.4 6 0 0 6 6 6 1 His Kinase A (phospho-acceptor) domain DUF2365 PF10157.4 KKK25982.1 - 0.00083 19.2 15.8 1.6 8.6 0.1 6.9 6 1 0 7 7 7 2 Uncharacterized conserved protein (DUF2365) AAA_13 PF13166.1 KKK25982.1 - 0.027 12.9 30.9 0.057 11.8 2.7 4.1 1 1 2 4 4 4 0 AAA domain NOD PF06816.8 KKK25982.1 - 0.039 13.0 0.1 1.1 8.3 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein PilJ PF13675.1 KKK25982.1 - 0.081 13.2 8.6 10 6.4 0.1 6.0 3 2 4 7 7 7 0 Type IV pili methyl-accepting chemotaxis transducer N-term Scaffolding_pro PF11418.3 KKK25982.1 - 0.43 10.9 9.2 39 4.6 0.0 5.4 5 0 0 5 5 5 0 Phi29 scaffolding protein NAAA-beta PF15508.1 KKK25982.1 - 1.6 9.1 6.7 18 5.7 0.1 5.3 6 2 0 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Aldo_ket_red PF00248.16 KKK25984.1 - 5e-65 219.1 0.0 6.3e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4202 PF13875.1 KKK25986.1 - 1.4e-52 177.9 0.0 1.6e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF2173 PF09941.4 KKK25986.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) Ribosomal_S25 PF03297.10 KKK25987.1 - 1.5e-27 95.6 0.6 1.5e-27 95.6 0.4 1.9 2 0 0 2 2 2 1 S25 ribosomal protein WD40 PF00400.27 KKK25987.1 - 0.0014 18.4 1.5 2 8.4 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat MarR_2 PF12802.2 KKK25987.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 MarR family TPR_1 PF00515.23 KKK25988.1 - 4.1e-37 124.2 23.4 1.7e-07 30.5 0.1 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 KKK25988.1 - 6.4e-36 121.8 27.7 3.8e-11 42.4 0.7 8.0 5 2 4 9 9 9 8 TPR repeat TPR_2 PF07719.12 KKK25988.1 - 1.8e-34 114.8 23.0 6.4e-05 22.5 0.0 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 KKK25988.1 - 5.2e-28 97.0 16.2 2.4e-21 75.6 0.2 5.0 2 1 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KKK25988.1 - 1.7e-24 85.8 21.2 2e-08 34.7 0.1 8.1 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 KKK25988.1 - 5.3e-23 81.1 15.0 5.3e-06 26.6 0.6 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KKK25988.1 - 8.3e-22 75.2 6.4 0.0063 16.2 0.0 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 KKK25988.1 - 2.9e-21 75.1 16.8 9.2e-05 22.3 0.2 8.2 6 1 2 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 KKK25988.1 - 7e-18 63.5 11.3 0.31 11.8 0.0 9.7 6 2 2 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 KKK25988.1 - 4e-13 48.4 17.3 0.091 13.0 0.0 8.8 10 1 1 11 11 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 KKK25988.1 - 3.7e-08 33.3 12.1 0.92 10.1 0.2 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK25988.1 - 6.4e-07 28.7 11.0 0.36 10.7 0.0 7.3 7 1 0 7 7 7 1 Tetratricopeptide repeat MIT PF04212.13 KKK25988.1 - 0.0035 17.2 2.8 0.095 12.5 0.2 3.6 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 KKK25988.1 - 0.011 15.6 5.1 9 6.2 0.2 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 KKK25988.1 - 0.048 13.5 2.4 5.5 6.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Med23 PF11573.3 KKK25988.1 - 0.056 10.7 0.1 0.12 9.6 0.0 1.4 2 0 0 2 2 2 0 Mediator complex subunit 23 ChAPs PF09295.5 KKK25988.1 - 0.072 11.8 0.8 9.9 4.7 0.0 3.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.18 KKK25988.1 - 0.09 11.7 1.6 0.33 9.9 0.2 2.7 3 1 0 3 3 3 0 FAT domain Acyltransferase PF01553.16 KKK25989.1 - 2.8e-33 114.1 0.0 4.5e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF788 PF05620.6 KKK25991.1 - 1.8e-45 154.8 0.0 2e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) ACC_central PF08326.7 KKK25992.1 - 8.3e-247 820.8 0.0 1.1e-246 820.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KKK25992.1 - 1.2e-182 607.6 0.0 2.5e-182 606.6 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KKK25992.1 - 1.7e-51 174.5 0.0 6.3e-51 172.6 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KKK25992.1 - 4.9e-24 84.5 0.1 9.3e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KKK25992.1 - 1.1e-22 80.0 0.0 1.1e-19 70.3 0.0 3.6 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KKK25992.1 - 4.6e-16 58.2 0.1 1.2e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KKK25992.1 - 3.7e-09 36.5 0.0 8.8e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KKK25992.1 - 3.4e-08 32.6 0.0 0.019 13.7 0.0 3.2 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK25992.1 - 0.00034 20.0 0.0 0.00071 19.0 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KKK25992.1 - 0.0062 16.4 0.0 0.022 14.6 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KKK25992.1 - 0.12 11.8 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain RINGv PF12906.2 KKK25993.1 - 2.9e-14 52.8 9.8 5.7e-14 51.8 6.8 1.5 1 0 0 1 1 1 1 RING-variant domain HeLo PF14479.1 KKK25993.1 - 0.013 15.2 0.1 0.065 12.9 0.1 2.0 1 1 0 1 1 1 0 Prion-inhibition and propagation Peptidase_S64 PF08192.6 KKK25993.1 - 0.3 9.3 0.0 0.46 8.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Pkinase_Tyr PF07714.12 KKK25993.1 - 0.33 9.9 0.0 0.9 8.5 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase zf-RING_2 PF13639.1 KKK25993.1 - 0.57 10.0 8.7 1.3 8.9 6.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KKK25993.1 - 1.6 8.3 7.6 3.2 7.3 5.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NUDE_C PF04880.8 KKK25994.1 - 3.5e-48 164.0 2.3 3.5e-48 164.0 1.6 4.2 3 1 1 4 4 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 KKK25994.1 - 0.00014 22.0 6.9 0.00014 22.0 4.8 4.1 2 1 2 4 4 4 1 Protein of unknown function (DUF904) BAR_2 PF10455.4 KKK25994.1 - 0.0018 17.2 7.7 0.0033 16.3 5.3 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking WEMBL PF05701.6 KKK25994.1 - 0.0019 16.7 26.1 0.0027 16.2 18.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light LPP PF04728.8 KKK25994.1 - 0.044 13.5 0.2 0.39 10.5 0.3 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Cep57_MT_bd PF06657.8 KKK25994.1 - 0.049 13.5 20.7 0.37 10.7 2.1 3.8 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Myosin_tail_1 PF01576.14 KKK25994.1 - 0.056 11.1 29.3 0.1 10.3 20.3 1.3 1 0 0 1 1 1 0 Myosin tail DUF1110 PF06533.7 KKK25994.1 - 0.061 13.1 0.5 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) ApoO PF09769.4 KKK25994.1 - 0.15 11.7 2.9 0.63 9.7 2.0 2.1 1 0 0 1 1 1 0 Apolipoprotein O Chibby PF14645.1 KKK25994.1 - 0.25 11.2 10.8 0.63 9.9 0.3 2.8 1 1 1 2 2 2 0 Chibby family HlyD_2 PF12700.2 KKK25994.1 - 0.33 10.0 10.2 0.49 9.4 7.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DUF1664 PF07889.7 KKK25994.1 - 0.34 10.7 10.5 0.06 13.1 3.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 KKK25994.1 - 0.47 10.2 31.0 0.22 11.3 15.2 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.8 KKK25994.1 - 0.69 9.4 11.8 1.5 8.2 8.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tho2 PF11262.3 KKK25994.1 - 0.69 8.9 13.9 1.1 8.2 1.5 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Tropomyosin_1 PF12718.2 KKK25994.1 - 0.74 9.6 33.6 1.7 8.5 15.6 3.5 2 1 1 3 3 3 0 Tropomyosin like ADIP PF11559.3 KKK25994.1 - 1.1 9.1 30.2 1.2 8.9 1.8 3.9 2 1 2 4 4 3 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 KKK25994.1 - 1.2 6.8 19.9 3.1 5.5 9.6 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 KKK25994.1 - 1.4 6.1 24.8 2.2 5.4 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 KKK25994.1 - 1.6 8.1 27.1 20 4.4 18.6 2.4 1 1 0 1 1 1 0 Intermediate filament protein DUF972 PF06156.8 KKK25994.1 - 1.9 8.8 20.8 0.31 11.3 2.0 3.2 2 1 2 4 4 3 0 Protein of unknown function (DUF972) MAD PF05557.8 KKK25994.1 - 2 6.4 33.3 2.1 6.3 18.8 2.6 2 1 0 2 2 2 0 Mitotic checkpoint protein HlyD PF00529.15 KKK25994.1 - 5.1 6.3 14.4 8.5 5.5 10.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Peptidase_S46 PF10459.4 KKK25994.1 - 5.6 5.2 11.0 7.6 4.8 7.6 1.1 1 0 0 1 1 1 0 Peptidase S46 ERM PF00769.14 KKK25994.1 - 5.9 6.3 31.9 1e+02 2.3 20.9 2.7 2 1 0 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 KKK25994.1 - 6.3 5.1 20.4 9.8 4.4 14.1 1.2 1 0 0 1 1 1 0 AAA domain DMPK_coil PF08826.5 KKK25994.1 - 7.7 6.5 29.7 0.31 10.9 1.5 4.4 4 1 1 5 5 4 0 DMPK coiled coil domain like IncA PF04156.9 KKK25994.1 - 7.7 6.0 34.6 3 7.4 10.4 2.6 2 1 1 3 3 3 0 IncA protein Seryl_tRNA_N PF02403.17 KKK25994.1 - 9.2 6.3 25.5 0.37 10.8 7.4 3.2 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Cupin_2 PF07883.6 KKK25995.1 - 4.2e-11 42.1 0.0 3.5e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KKK25995.1 - 3.4e-05 23.1 0.0 0.0037 16.6 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 KKK25995.1 - 0.00027 20.6 0.1 0.064 12.9 0.1 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 KKK25995.1 - 0.00046 19.8 0.1 0.0015 18.1 0.0 1.8 2 0 0 2 2 2 1 Cupin SprB PF13573.1 KKK25995.1 - 0.07 12.7 0.2 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 SprB repeat ADH_zinc_N PF00107.21 KKK25996.1 - 2.4e-16 59.4 0.0 3.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK25996.1 - 3.2e-07 31.2 0.0 5.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KKK25996.1 - 0.023 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox_3 PF13738.1 KKK25997.1 - 3.1e-18 66.5 0.0 4.9e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK25997.1 - 8.5e-16 57.2 0.0 2.4e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK25997.1 - 1.1e-07 31.7 0.0 3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK25997.1 - 0.0001 22.0 0.1 0.0003 20.5 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KKK25997.1 - 0.0022 17.1 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.1 KKK25997.1 - 0.022 13.7 0.1 0.19 10.6 0.0 2.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KKK25997.1 - 0.098 13.0 0.0 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 KKK25998.1 - 2.2e-40 138.5 0.0 2.5e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 KKK25999.1 - 3.3e-43 147.7 0.0 4.5e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK25999.1 - 7.7e-09 34.7 0.3 5.3e-08 32.0 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Patatin PF01734.17 KKK25999.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase ADH_N PF08240.7 KKK26000.1 - 5.5e-30 103.3 1.3 1.8e-29 101.7 0.0 2.3 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK26000.1 - 1.8e-19 69.5 0.1 3.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK26000.1 - 0.001 19.9 0.0 0.0032 18.3 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 KKK26000.1 - 0.0027 16.2 0.2 0.0038 15.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein AdoHcyase_NAD PF00670.16 KKK26000.1 - 0.0041 16.9 0.4 0.11 12.2 0.3 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.22 KKK26000.1 - 0.0063 16.8 0.0 0.039 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 KKK26000.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KKK26000.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 KKK26001.1 - 5.9e-52 176.2 0.0 7e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DLH PF01738.13 KKK26002.1 - 1.4e-23 83.3 0.0 1.7e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK26002.1 - 2.2e-06 27.4 0.0 3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KKK26002.1 - 0.02 13.9 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 KKK26002.1 - 0.022 14.6 0.0 0.14 12.0 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK26002.1 - 0.069 12.6 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold LIM_bind PF01803.11 KKK26003.1 - 3.4e-77 258.8 0.8 3.4e-77 258.8 0.5 4.3 3 2 1 4 4 4 1 LIM-domain binding protein Transaldolase PF00923.14 KKK26004.1 - 6e-76 255.3 0.0 6.9e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Chorismate_synt PF01264.16 KKK26004.1 - 0.046 12.2 0.0 0.065 11.7 0.0 1.1 1 0 0 1 1 1 0 Chorismate synthase AA_permease_2 PF13520.1 KKK26005.1 - 2.5e-51 174.5 53.3 3e-51 174.3 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK26005.1 - 2.4e-22 78.9 48.1 3.3e-22 78.4 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 KKK26005.1 - 0.073 12.8 0.2 0.073 12.8 0.1 3.1 2 0 0 2 2 2 0 Gram positive anchor Aldedh PF00171.17 KKK26006.1 - 1.5e-161 537.8 0.2 1.6e-161 537.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KKK26006.1 - 0.028 13.6 0.1 0.33 10.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1487) DUF126 PF01989.11 KKK26006.1 - 1.6 8.4 4.3 10 5.8 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function DUF126 MFS_1 PF07690.11 KKK26007.1 - 1.6e-42 145.4 45.6 1.6e-42 145.4 31.6 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF726 PF05277.7 KKK26008.1 - 3.2e-113 378.1 0.6 4.1e-113 377.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KKK26008.1 - 0.016 15.1 1.5 0.022 14.6 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3353 PF11833.3 KKK26008.1 - 0.018 14.5 0.0 0.049 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Abhydrolase_1 PF00561.15 KKK26008.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF663 PF04950.7 KKK26009.1 - 2.8e-97 325.2 0.0 4.4e-97 324.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KKK26009.1 - 1.8e-24 85.0 0.0 3.9e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.6 KKK26010.1 - 4.9e-38 128.5 0.0 2.3e-36 123.1 0.0 2.5 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 KKK26010.1 - 2.1e-05 24.2 0.1 0.019 14.8 0.0 3.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KKK26010.1 - 0.0094 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region DUF4427 PF14468.1 KKK26010.1 - 0.093 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) Zn_clus PF00172.13 KKK26011.1 - 1.7e-05 24.6 12.3 1.7e-05 24.6 8.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KKK26012.1 - 8.4e-35 120.1 0.0 1.1e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 KKK26013.1 - 6.5e-47 160.0 48.1 8e-42 143.2 21.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KKK26013.1 - 9e-26 90.2 41.8 1.8e-23 82.6 20.4 2.1 2 0 0 2 2 2 2 Amino acid permease Nodulin_late PF07127.6 KKK26013.1 - 7.1 6.8 6.7 0.65 10.1 0.9 2.2 2 0 0 2 2 2 0 Late nodulin protein Glu-tRNAGln PF02686.10 KKK26014.1 - 3.2e-06 26.8 0.9 1.2e-05 25.0 0.2 2.0 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit MscS_porin PF12795.2 KKK26014.1 - 0.03 13.6 0.6 0.043 13.1 0.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain SNAP PF14938.1 KKK26015.1 - 1.8e-113 378.3 14.4 2.1e-113 378.2 10.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 KKK26015.1 - 3.5e-06 26.4 9.6 1.8 8.5 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 KKK26015.1 - 3.8e-05 23.8 13.7 1 9.9 0.1 6.1 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KKK26015.1 - 5.6e-05 22.7 17.6 0.049 13.2 1.2 4.0 2 2 1 3 3 3 3 TPR repeat TPR_12 PF13424.1 KKK26015.1 - 9.6e-05 22.2 18.8 0.033 14.1 4.9 4.0 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK26015.1 - 0.0016 18.8 15.9 2.2 9.1 0.6 6.0 2 1 4 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK26015.1 - 0.0019 17.9 22.1 2.3 8.3 1.3 6.7 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KKK26015.1 - 0.0077 15.8 20.0 0.64 9.7 0.6 5.9 5 2 2 7 7 7 3 Tetratricopeptide repeat DUF1744 PF08490.7 KKK26015.1 - 0.023 13.2 0.1 0.035 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) DUF2811 PF10929.3 KKK26015.1 - 0.043 13.8 0.1 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Imm16 PF15565.1 KKK26015.1 - 0.046 13.5 0.3 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 16 TPR_16 PF13432.1 KKK26015.1 - 0.053 14.2 17.8 1.6 9.5 0.3 4.2 1 1 4 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 KKK26015.1 - 0.23 11.6 14.1 0.71 10.0 0.9 3.2 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.15 KKK26015.1 - 0.28 11.8 20.5 0.99 10.2 0.6 7.0 8 0 0 8 8 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.1 KKK26015.1 - 0.59 10.0 18.0 2.6 8.0 0.2 5.5 4 2 3 7 7 6 0 Tetratricopeptide repeat Pyr_redox_3 PF13738.1 KKK26016.1 - 4.2e-25 89.0 0.0 8e-24 84.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK26016.1 - 5.2e-13 48.0 0.1 4.1e-11 41.7 0.1 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK26016.1 - 3.1e-11 43.1 0.0 8.5e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK26016.1 - 4.8e-09 36.1 0.0 3.6e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK26016.1 - 4e-08 33.3 0.0 0.0001 22.2 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK26016.1 - 7.5e-08 31.6 0.0 0.0013 17.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KKK26016.1 - 4.7e-06 25.7 0.1 0.00026 20.0 0.0 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK26016.1 - 0.00098 19.4 0.0 0.057 13.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK26016.1 - 0.0016 17.5 0.0 0.089 11.8 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KKK26016.1 - 0.0086 15.1 0.0 0.022 13.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 KKK26016.1 - 0.02 13.7 0.0 2.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KKK26016.1 - 0.031 14.3 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KKK26016.1 - 0.064 12.1 0.0 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK26016.1 - 0.078 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 KKK26016.1 - 0.13 12.4 0.0 0.7 10.1 0.0 2.1 3 0 0 3 3 3 0 Putative NAD(P)-binding DUF1365 PF07103.6 KKK26017.1 - 1.6e-14 53.6 0.0 9.4e-10 37.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1365) HTH_Tnp_Tc5 PF03221.11 KKK26018.1 - 5.9e-18 64.4 0.0 1.1e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KKK26018.1 - 9.2e-06 24.9 0.1 1.8e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 KKK26018.1 - 0.0024 17.4 0.1 0.0056 16.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 KKK26018.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.17 KKK26018.1 - 0.026 14.2 0.0 0.069 12.8 0.0 1.7 1 0 0 1 1 1 0 MarR family Sigma70_r4 PF04545.11 KKK26018.1 - 0.07 12.4 0.1 0.14 11.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.1 KKK26018.1 - 0.072 12.7 0.7 0.44 10.2 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain HTH_10 PF04967.7 KKK26018.1 - 0.078 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_28 PF13518.1 KKK26018.1 - 0.11 12.4 1.1 12 6.0 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 KKK26018.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MGC-24 PF05283.6 KKK26019.1 - 2.6 7.8 6.4 4.6 7.0 4.4 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) CLU PF13236.1 KKK26020.1 - 6.4e-81 270.9 0.0 1.3e-80 269.9 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KKK26020.1 - 5e-53 179.5 0.0 1.6e-52 177.8 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 KKK26020.1 - 7.5e-27 93.2 0.1 2.2e-26 91.7 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 KKK26020.1 - 4.2e-06 26.5 1.4 1.3e-05 25.0 1.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat EnY2 PF10163.4 KKK26020.1 - 0.017 15.0 0.1 0.068 13.0 0.0 2.1 1 0 0 1 1 1 0 Transcription factor e(y)2 TPR_10 PF13374.1 KKK26020.1 - 0.029 14.2 0.1 0.085 12.8 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK26020.1 - 0.074 13.0 0.1 0.28 11.1 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat BRF1 PF07741.8 KKK26020.1 - 0.45 10.7 9.0 0.55 10.4 2.6 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ldh_1_N PF00056.18 KKK26025.1 - 1.7e-45 154.3 0.2 2.8e-45 153.5 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KKK26025.1 - 3.4e-39 134.3 0.0 4.5e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KKK26025.1 - 0.00022 20.0 0.0 0.00035 19.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 KKK26025.1 - 0.005 16.1 0.0 0.052 12.8 0.0 2.2 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.1 KKK26025.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 KKK26025.1 - 0.042 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Phosphodiest PF01663.17 KKK26027.1 - 1e-17 64.5 0.7 2.1e-16 60.2 0.5 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KKK26027.1 - 8.7e-05 21.8 0.0 0.00032 19.9 0.0 1.8 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KKK26027.1 - 0.0082 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 KKK26027.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF2423 PF10338.4 KKK26028.1 - 4.9e-20 71.2 2.2 4.9e-20 71.2 1.5 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Presenilin PF01080.12 KKK26028.1 - 0.9 8.2 3.2 1 8.1 2.2 1.1 1 0 0 1 1 1 0 Presenilin HMG14_17 PF01101.13 KKK26028.1 - 1.4 9.7 11.8 0.053 14.2 4.0 1.8 1 1 1 2 2 2 0 HMG14 and HMG17 PINIT PF14324.1 KKK26029.1 - 4.6e-44 149.9 0.1 1e-43 148.8 0.0 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KKK26029.1 - 2.5e-21 74.9 7.0 4.7e-21 74.0 4.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 KKK26029.1 - 7.7e-08 31.6 1.7 2.7e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.3 KKK26029.1 - 3.2e-06 26.5 2.1 7.7e-06 25.3 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit OGFr_III PF04680.8 KKK26029.1 - 0.085 13.0 2.6 0.28 11.3 1.8 1.9 1 0 0 1 1 1 0 Opioid growth factor receptor repeat zf-Sec23_Sec24 PF04810.10 KKK26029.1 - 0.16 11.5 1.7 0.51 9.9 0.7 2.1 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger TRAPP PF04051.11 KKK26030.1 - 9.9e-46 155.0 0.0 1.1e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CBFD_NFYB_HMF PF00808.18 KKK26031.1 - 5.1e-19 68.1 0.5 8.4e-19 67.3 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK26031.1 - 1.5e-12 47.4 0.1 2.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KKK26031.1 - 0.04 13.7 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 KKK26032.1 - 1.2e-112 376.2 1.2 1.2e-112 376.2 0.8 2.2 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 KKK26032.1 - 8.7e-05 22.3 4.6 0.00048 19.9 1.4 2.7 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG2 PF06148.6 KKK26032.1 - 0.0023 17.8 6.8 0.0023 17.8 4.7 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 KKK26032.1 - 0.0043 15.9 7.6 0.0043 15.9 5.3 1.7 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG5 PF10392.4 KKK26032.1 - 0.0063 16.4 7.1 0.013 15.4 3.5 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Gp-FAR-1 PF05823.7 KKK26032.1 - 0.02 14.8 2.0 0.071 13.0 1.4 2.0 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Vps51 PF08700.6 KKK26032.1 - 0.11 12.4 4.4 0.11 12.3 1.0 2.6 2 0 0 2 2 2 0 Vps51/Vps67 Sec8_exocyst PF04048.9 KKK26032.1 - 0.42 10.2 10.9 0.051 13.2 3.4 2.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain FUSC PF04632.7 KKK26032.1 - 1.5 7.1 5.5 2.4 6.4 3.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4206 PF13901.1 KKK26032.1 - 1.6 8.2 5.4 1.2 8.6 1.2 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4206) RRM_2 PF04059.7 KKK26033.1 - 2.3e-40 136.4 1.0 4.8e-40 135.4 0.4 1.8 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.17 KKK26033.1 - 4.3e-10 39.0 0.0 0.038 13.6 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK26033.1 - 0.0024 17.7 0.1 0.67 9.9 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK26033.1 - 0.016 15.0 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fcf2 PF08698.6 KKK26035.1 - 1e-31 108.8 0.1 2.7e-31 107.4 0.0 1.7 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.15 KKK26036.1 - 7e-43 146.2 0.1 9.2e-43 145.8 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.17 KKK26037.1 - 6.2e-26 90.0 0.0 1.8e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Mito_carr PF00153.22 KKK26038.1 - 1.3e-69 229.9 0.4 3.1e-23 81.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 KKK26039.1 - 3e-35 119.6 0.0 1.2e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK26039.1 - 8.5e-20 70.5 0.0 7.4e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK26039.1 - 3.6e-16 58.7 0.0 7.7e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KKK26039.1 - 0.0055 16.1 0.2 0.38 10.2 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 KKK26039.1 - 0.026 14.2 0.2 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 Cas_Cas2CT1978 PF09707.5 KKK26039.1 - 0.097 12.6 0.0 6.8 6.7 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF605 PF04652.11 KKK26039.1 - 0.77 9.0 14.4 1 8.6 10.0 1.1 1 0 0 1 1 1 0 Vta1 like Tom7 PF08038.7 KKK26040.1 - 8.1e-21 73.2 0.2 9.3e-21 73.0 0.2 1.1 1 0 0 1 1 1 1 TOM7 family NUMOD3 PF07460.6 KKK26040.1 - 0.067 13.0 0.1 0.1 12.5 0.0 1.4 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) Ribosomal_L28e PF01778.12 KKK26041.1 - 5.1e-45 152.6 0.4 6.9e-45 152.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.5 KKK26042.1 - 1.8e-48 163.5 0.0 2e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF3829 PF12889.2 KKK26042.1 - 0.089 11.9 0.0 0.097 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Lactonase PF10282.4 KKK26043.1 - 7e-79 265.3 0.0 1.5e-78 264.3 0.0 1.4 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.7 KKK26043.1 - 0.0023 17.9 1.8 0.32 11.0 0.4 2.8 2 0 0 2 2 2 2 Putative Ig domain Glyco_hydro_72 PF03198.9 KKK26049.1 - 4.7e-130 433.1 4.0 6.3e-130 432.7 2.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KKK26049.1 - 1.5e-23 83.0 5.2 4.6e-23 81.4 3.6 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 KKK26049.1 - 6.5e-05 21.9 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain GCV_T PF01571.16 KKK26062.1 - 3.1e-58 196.6 0.0 4.6e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KKK26062.1 - 9.4e-19 67.2 0.2 2e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain POP1 PF06978.6 KKK26062.1 - 0.0039 16.8 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 Aa_trans PF01490.13 KKK26063.1 - 3.4e-29 101.5 34.0 4.3e-29 101.2 23.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CBF PF03914.12 KKK26064.1 - 8.3e-47 158.6 0.8 6.2e-46 155.8 0.0 2.8 2 0 0 2 2 2 1 CBF/Mak21 family V-ATPase_H_N PF03224.9 KKK26065.1 - 4.4e-83 278.9 0.0 6.5e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KKK26065.1 - 2.7e-40 136.9 0.0 8.6e-40 135.3 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H HCaRG PF07258.9 KKK26065.1 - 0.016 14.7 0.1 0.079 12.5 0.0 2.1 2 1 0 2 2 2 0 HCaRG protein HEAT_EZ PF13513.1 KKK26065.1 - 0.41 11.2 2.4 8 7.0 0.0 3.8 3 2 0 3 3 3 0 HEAT-like repeat WD40 PF00400.27 KKK26066.1 - 6.2e-54 178.0 8.5 2e-09 36.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KKK26066.1 - 0.0055 14.8 3.8 4 5.4 0.6 4.4 1 1 2 3 3 3 1 Nucleoporin Nup120/160 AAA PF00004.24 KKK26067.1 - 9e-14 51.8 0.0 1.7e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK26067.1 - 1.5e-10 41.3 0.0 4.6e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK26067.1 - 8.7e-09 35.6 0.0 3.4e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain BAH PF01426.13 KKK26067.1 - 7.2e-06 25.7 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_17 PF13207.1 KKK26067.1 - 2.3e-05 25.1 0.0 0.00033 21.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KKK26067.1 - 0.0012 18.5 2.3 0.0033 17.1 0.2 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KKK26067.1 - 0.0017 18.3 0.0 0.0042 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KKK26067.1 - 0.0032 17.1 0.0 0.012 15.2 0.0 2.0 2 1 0 2 2 2 1 NACHT domain DUF2075 PF09848.4 KKK26067.1 - 0.0093 14.9 0.0 0.022 13.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KKK26067.1 - 0.017 14.7 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 KKK26067.1 - 0.018 13.6 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK26067.1 - 0.028 14.7 0.0 0.072 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK26067.1 - 0.03 14.1 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 KKK26067.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 KKK26067.1 - 0.067 12.1 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase Arch_ATPase PF01637.13 KKK26067.1 - 0.071 12.8 0.0 0.8 9.3 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase TMF_TATA_bd PF12325.3 KKK26068.1 - 2.8e-44 149.7 11.5 2.8e-44 149.7 7.9 6.0 3 2 3 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KKK26068.1 - 2.4e-17 62.4 12.9 2.4e-17 62.4 9.0 9.1 6 3 3 9 9 9 2 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 KKK26068.1 - 4.3 7.0 54.2 0.13 12.0 6.4 5.6 2 2 2 5 5 5 0 Laminin Domain II NPV_P10 PF05531.7 KKK26068.1 - 5 7.4 24.7 0.44 10.8 3.4 5.7 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 KKK26068.1 - 5.2 6.4 76.3 0.52 9.7 4.6 3.7 2 1 1 3 3 3 0 Intermediate filament protein Reo_sigmaC PF04582.7 KKK26068.1 - 7.4 5.6 23.7 0.055 12.6 1.0 4.3 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Ank_2 PF12796.2 KKK26069.1 - 3.3e-41 139.5 4.2 4.1e-17 62.2 0.5 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK26069.1 - 9.1e-33 111.5 1.3 2.4e-09 37.1 0.1 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 KKK26069.1 - 5.9e-32 107.8 2.9 3.6e-06 26.5 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KKK26069.1 - 1.5e-30 104.9 5.3 1.4e-07 31.8 0.1 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK26069.1 - 2.2e-24 83.0 1.5 8.6e-05 22.4 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Dabb PF07876.7 KKK26070.1 - 6.2e-24 84.2 0.0 6.9e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain tRNA-synt_2b PF00587.20 KKK26071.1 - 2.9e-33 114.8 0.0 5.1e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) NUDIX PF00293.23 KKK26071.1 - 8.1e-24 83.7 0.3 1.5e-23 82.9 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain HGTP_anticodon PF03129.15 KKK26071.1 - 1.6e-10 40.8 0.1 4.7e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KKK26071.1 - 0.15 10.7 0.1 0.47 9.1 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) KH_3 PF13014.1 KKK26072.1 - 0.17 11.5 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 KH domain Prefoldin PF02996.12 KKK26073.1 - 1e-12 47.7 0.9 6.3e-12 45.2 0.6 1.9 1 1 0 1 1 1 1 Prefoldin subunit Glu-tRNAGln PF02686.10 KKK26073.1 - 0.0094 15.7 0.0 0.024 14.4 0.0 1.6 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit TMF_TATA_bd PF12325.3 KKK26073.1 - 0.044 13.5 0.2 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DASH_Hsk3 PF08227.6 KKK26073.1 - 0.059 13.5 2.7 0.14 12.3 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF883 PF05957.8 KKK26073.1 - 0.23 11.9 1.8 14 6.1 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FAD_binding_1 PF00667.15 KKK26081.1 - 6.6e-43 146.7 0.0 9.2e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KKK26081.1 - 3e-10 40.6 0.0 7.7e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain EF-hand_1 PF00036.27 KKK26083.1 - 4.1e-23 78.8 9.9 2.6e-07 29.4 0.1 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KKK26083.1 - 1.6e-21 74.2 4.5 3.2e-05 23.4 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 KKK26083.1 - 3.2e-20 72.0 2.9 3.4e-13 49.5 0.3 3.0 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KKK26083.1 - 5.3e-16 57.1 8.5 0.00044 19.4 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KKK26083.1 - 3.7e-13 48.8 12.4 2.3e-05 23.8 0.8 4.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KKK26083.1 - 3.1e-07 30.0 5.2 0.016 14.9 0.1 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KKK26083.1 - 0.0014 18.4 0.3 0.42 10.5 0.0 3.9 3 1 1 4 4 4 1 EF-hand domain EF-hand_10 PF14788.1 KKK26083.1 - 0.021 14.4 0.6 1.7 8.3 0.0 3.2 3 0 0 3 3 3 0 EF hand EF-hand_2 PF09068.6 KKK26083.1 - 0.036 14.1 0.0 29 4.7 0.0 3.8 4 1 0 4 4 4 0 EF hand Zn_clus PF00172.13 KKK26083.1 - 0.044 13.7 3.3 0.097 12.6 2.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 KKK26084.1 - 8.3e-25 87.6 0.1 1.4e-24 86.8 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK26084.1 - 1.1e-14 53.8 0.0 4.5e-14 51.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK26084.1 - 4.3e-07 29.7 0.0 7.8e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK26084.1 - 0.00042 19.6 0.0 0.00082 18.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 KKK26084.1 - 0.0018 17.0 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family UPF0565 PF10561.4 KKK26084.1 - 0.031 13.1 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 TRI12 PF06609.8 KKK26085.1 - 2.8e-29 101.8 26.0 3.5e-29 101.4 18.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KKK26085.1 - 3.8e-21 75.1 49.1 1.7e-20 73.0 31.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK26085.1 - 2.5e-07 29.6 10.3 2.5e-07 29.6 7.1 3.6 3 1 1 4 4 4 1 Sugar (and other) transporter DUF4212 PF13937.1 KKK26085.1 - 3 7.9 10.1 2.9 7.9 0.2 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4212) Methyltransf_23 PF13489.1 KKK26086.1 - 4e-18 65.6 0.0 6.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK26086.1 - 1.3e-11 44.8 0.0 4.8e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK26086.1 - 3.1e-10 40.3 0.0 7.6e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK26086.1 - 4.3e-09 36.1 0.0 6.4e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK26086.1 - 5e-09 36.7 0.0 8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK26086.1 - 9.5e-05 22.4 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK26086.1 - 0.00037 20.7 0.0 0.00069 19.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KKK26086.1 - 0.053 14.3 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 KKK26086.1 - 0.064 12.6 0.0 7.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Nodulation protein S (NodS) Prp18 PF02840.10 KKK26086.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain PC_rep PF01851.17 KKK26087.1 - 2.5e-40 134.4 18.3 1.3e-09 37.7 0.0 9.6 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KKK26087.1 - 6.7e-17 61.5 0.3 1.3e-12 47.8 0.0 3.6 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KKK26087.1 - 1.2e-09 38.4 0.8 3.7e-06 27.2 0.0 4.0 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KKK26087.1 - 7.6e-07 28.6 0.0 3 8.1 0.0 4.6 4 0 0 4 4 4 3 HEAT repeat HEAT_PBS PF03130.11 KKK26087.1 - 0.032 14.6 1.8 0.8 10.3 0.0 3.7 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 KKK26087.1 - 0.066 13.1 0.2 5.2 7.0 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 GPI-anchored PF10342.4 KKK26090.1 - 8.7e-14 51.7 0.0 2.1e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 KKK26090.1 - 3.9e-07 30.3 3.6 3.9e-07 30.3 2.5 1.6 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 TIP41 PF04176.8 KKK26091.1 - 8.2e-81 269.6 0.4 1.1e-80 269.1 0.3 1.2 1 0 0 1 1 1 1 TIP41-like family Na_Ca_ex PF01699.19 KKK26092.1 - 2.7e-22 78.9 24.0 1.1e-14 54.2 3.0 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SlyX PF04102.7 KKK26092.1 - 0.036 14.4 13.1 0.2 12.0 1.8 3.6 3 0 0 3 3 3 0 SlyX N_methyl_2 PF13544.1 KKK26092.1 - 0.1 12.0 0.0 0.1 12.0 0.0 2.7 2 0 0 2 2 2 0 Type IV pilin N-term methylation site GFxxxE DUF3169 PF11368.3 KKK26092.1 - 0.29 10.3 5.4 0.043 13.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) PIG-P PF08510.7 KKK26092.1 - 1 8.9 4.3 4.6 6.8 0.0 3.0 2 0 0 2 2 2 0 PIG-P DUF4131 PF13567.1 KKK26092.1 - 4.2 6.7 7.9 9.3 5.6 0.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) SRPRB PF09439.5 KKK26093.1 - 6.8e-26 90.5 0.2 4.2e-24 84.7 0.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KKK26093.1 - 6e-08 32.1 0.0 0.0039 16.4 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KKK26093.1 - 1.5e-06 28.1 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KKK26093.1 - 7.1e-06 26.1 0.3 2.2e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 KKK26093.1 - 9.7e-05 22.6 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 KKK26093.1 - 0.0011 18.4 0.0 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KKK26093.1 - 0.0013 18.2 0.1 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 KKK26093.1 - 0.0014 18.1 0.1 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 KKK26093.1 - 0.0019 17.7 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF258 PF03193.11 KKK26093.1 - 0.003 16.7 0.1 0.0068 15.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK26093.1 - 0.01 15.9 0.1 0.02 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 KKK26093.1 - 0.022 15.2 0.1 0.29 11.6 0.1 2.4 2 1 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KKK26093.1 - 0.049 13.2 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK26093.1 - 0.052 13.4 0.3 0.084 12.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KKK26093.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 KKK26093.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KKK26093.1 - 0.069 13.9 0.1 0.17 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK26093.1 - 0.084 13.1 0.3 0.16 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KKK26093.1 - 0.092 12.1 0.3 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 KKK26093.1 - 0.11 12.3 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK26093.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KKK26093.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Septin PF00735.13 KKK26093.1 - 0.19 10.7 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.24 KKK26093.1 - 0.24 11.6 1.0 0.79 9.9 0.7 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AA_kinase PF00696.23 KKK26094.1 - 1.9e-38 132.4 0.6 2.8e-38 131.8 0.4 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KKK26094.1 - 1.2e-17 63.3 0.2 5e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 PUA domain PALP PF00291.20 KKK26095.1 - 1e-60 205.5 0.1 1.2e-60 205.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KKK26095.1 - 6.6e-09 35.4 0.1 2.7e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain ACP_syn_III_C PF08541.5 KKK26095.1 - 0.076 13.0 0.1 14 5.8 0.0 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Pkinase PF00069.20 KKK26096.1 - 3.8e-71 239.2 0.0 4.8e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK26096.1 - 1.6e-44 151.9 0.0 2.1e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK26096.1 - 1.8e-07 30.4 0.0 5.5e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KKK26096.1 - 3.8e-05 22.8 0.2 6.5e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KKK26096.1 - 0.019 14.2 0.1 0.041 13.2 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KKK26096.1 - 0.051 13.3 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NumbF PF06311.7 KKK26097.1 - 0.0042 17.1 1.1 0.0074 16.3 0.7 1.5 1 0 0 1 1 1 1 NUMB domain Peptidase_M76 PF09768.4 KKK26098.1 - 2e-73 245.4 2.9 2.4e-73 245.2 2.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M13 PF01431.16 KKK26098.1 - 0.063 12.4 0.1 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M13 SprT-like PF10263.4 KKK26098.1 - 0.33 10.5 7.2 0.061 12.9 1.4 2.2 1 1 2 3 3 3 0 SprT-like family Ank PF00023.25 KKK26099.1 - 2.1e-36 121.9 4.5 1.9e-10 39.9 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 KKK26099.1 - 3.6e-36 123.3 0.2 1.2e-16 60.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 KKK26099.1 - 1.1e-34 119.3 10.5 1.1e-34 119.3 7.3 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 KKK26099.1 - 3.2e-28 97.0 6.6 2.2e-09 37.2 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK26099.1 - 1e-26 92.7 12.3 1.3e-08 35.0 0.3 4.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK26099.1 - 7.2e-25 84.5 3.3 1.4e-08 34.1 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Cyclin PF08613.6 KKK26101.1 - 2.5e-34 118.8 0.0 3.1e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KKK26101.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.11 KKK26102.1 - 8.5e-44 149.6 53.2 8.5e-44 149.6 36.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK26102.1 - 4.2e-15 54.9 15.8 4.2e-15 54.9 11.0 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK26102.1 - 6.6e-14 51.3 12.2 6.6e-14 51.3 8.5 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Abhydrolase_8 PF06259.7 KKK26102.1 - 0.049 13.1 2.1 0.46 9.9 0.3 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase Peptidase_M49 PF03571.10 KKK26103.1 - 6.5e-61 206.0 0.0 8.3e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 COX6A PF02046.10 KKK26105.1 - 1.1e-38 131.6 0.4 1.3e-38 131.4 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos_2 PF14529.1 KKK26106.1 - 8.6e-14 51.1 0.0 2.4e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KKK26106.1 - 1.3e-13 51.4 0.1 2e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 KKK26106.1 - 0.016 15.1 1.0 0.038 13.9 0.7 1.7 1 0 0 1 1 1 0 GRF zinc finger Peptidase_M49 PF03571.10 KKK26107.1 - 1.4e-90 303.9 0.0 1.5e-90 303.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Apc5 PF12862.2 KKK26108.1 - 1.3e-36 124.3 5.1 3.4e-36 122.9 1.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 KKK26108.1 - 0.5 10.3 8.0 8.1 6.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF953 PF06110.6 KKK26109.1 - 3.1e-14 52.4 0.0 3.6e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 KKK26109.1 - 0.00035 20.1 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 KKK26109.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.6 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE FAD_binding_4 PF01565.18 KKK26110.1 - 4.9e-18 64.9 0.8 1.3e-17 63.5 0.5 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK26110.1 - 6e-08 32.4 0.2 1.2e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ParA PF10609.4 KKK26111.1 - 9e-36 121.6 0.0 2e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KKK26111.1 - 2.4e-15 56.4 0.0 3.4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KKK26111.1 - 4e-06 26.8 0.0 1.7e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KKK26111.1 - 1.1e-05 24.6 1.8 0.00045 19.3 0.2 2.7 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 KKK26111.1 - 0.0044 16.6 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KKK26111.1 - 0.0044 16.1 0.0 0.011 14.7 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ DUF258 PF03193.11 KKK26111.1 - 0.008 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zn_Tnp_IS1595 PF12760.2 KKK26111.1 - 0.077 12.8 0.1 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain AAA_25 PF13481.1 KKK26111.1 - 0.091 12.1 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KKK26111.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ChW PF07538.6 KKK26111.1 - 6.1 6.4 6.2 0.66 9.5 0.7 2.1 2 0 0 2 2 2 0 Clostridial hydrophobic W Asp PF00026.18 KKK26113.1 - 7.4e-65 219.2 9.8 8.8e-65 219.0 6.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK26113.1 - 2.2e-05 24.4 0.3 7.6e-05 22.7 0.2 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KKK26113.1 - 0.00021 21.7 3.3 0.33 11.4 0.6 2.9 2 1 0 2 2 2 2 Aspartyl protease zf-CSL PF05207.8 KKK26122.1 - 1.3e-17 63.0 1.5 2.3e-17 62.2 1.0 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KKK26122.1 - 0.0036 17.0 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1349 PF07081.6 KKK26123.1 - 3.2e-18 65.7 0.0 1.6e-16 60.1 0.0 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Proteasome PF00227.21 KKK26125.1 - 6e-47 159.4 0.1 7.1e-32 110.2 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KKK26125.1 - 4.8e-12 44.9 0.3 1e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature WBS_methylT PF12589.3 KKK26127.1 - 3.1e-17 62.8 1.6 5.1e-17 62.1 1.1 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KKK26127.1 - 5.3e-12 46.0 0.0 9.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK26127.1 - 1.6e-09 38.0 0.0 5.1e-09 36.4 0.0 1.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK26127.1 - 6.3e-07 29.0 0.0 9.8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK26127.1 - 1e-05 26.0 0.0 2.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK26127.1 - 1.4e-05 25.4 0.0 4.1e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK26127.1 - 4.5e-05 23.2 0.0 6.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK26127.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KKK26127.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KKK26127.1 - 0.0039 16.3 0.1 0.043 12.9 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KKK26127.1 - 0.014 14.4 0.0 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 KKK26127.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Erv26 PF04148.8 KKK26128.1 - 1.8e-92 308.4 0.1 2.1e-92 308.2 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 QueT PF06177.6 KKK26128.1 - 1.1 9.2 4.5 0.31 11.0 1.0 1.5 2 0 0 2 2 2 0 QueT transporter APP_N PF02177.11 KKK26129.1 - 0.012 15.5 0.2 2.7 7.9 0.0 2.1 1 1 1 2 2 2 0 Amyloid A4 N-terminal heparin-binding YjbE PF11106.3 KKK26129.1 - 0.11 12.5 0.3 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Toxin_29 PF08116.6 KKK26129.1 - 1.3 8.8 4.1 18 5.2 0.2 2.3 2 0 0 2 2 2 0 PhTx neurotoxin family Iso_dh PF00180.15 KKK26130.1 - 2.7e-83 279.8 0.0 3.4e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HSP70 PF00012.15 KKK26131.1 - 3.5e-10 38.4 0.3 2.8e-09 35.4 0.1 1.9 2 0 0 2 2 2 1 Hsp70 protein zf-SAP30 PF13866.1 KKK26131.1 - 0.017 14.7 0.1 0.04 13.5 0.1 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger MreB_Mbl PF06723.8 KKK26131.1 - 0.089 11.3 0.0 0.32 9.5 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein Peptidase_C13 PF01650.13 KKK26132.1 - 7e-41 140.2 0.1 9.9e-41 139.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Mito_carr PF00153.22 KKK26134.1 - 3.4e-44 148.4 9.5 1.8e-16 59.6 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3445 PF11927.3 KKK26135.1 - 1.6e-81 273.4 0.1 2e-81 273.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) 4HBT_3 PF13622.1 KKK26136.1 - 9.4e-43 146.7 0.2 1.5e-42 146.1 0.2 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KKK26136.1 - 5.1e-24 84.3 0.0 2.9e-12 46.3 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Succ_CoA_lig PF13607.1 KKK26136.1 - 0.061 12.9 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain PNP_UDP_1 PF01048.15 KKK26146.1 - 2.5e-10 39.7 0.8 2.3e-09 36.5 0.5 2.4 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 KKK26146.1 - 7.9e-10 38.0 0.0 1.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 KKK26146.1 - 2.9e-05 23.8 0.0 5.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KKK26146.1 - 0.00069 19.7 0.0 0.0077 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK26146.1 - 0.0022 17.9 0.0 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KKK26146.1 - 0.061 13.6 0.0 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.1 KKK26147.1 - 2.7e-35 120.1 0.7 1.3e-17 63.4 0.1 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 KKK26147.1 - 8.9e-32 108.0 1.5 3e-11 42.8 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KKK26147.1 - 8.1e-09 35.0 1.2 5.4e-06 25.9 0.0 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KKK26147.1 - 3.5e-07 29.6 0.7 0.043 13.7 0.0 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK26147.1 - 8.1e-07 28.7 0.1 0.76 10.1 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK26147.1 - 1.1e-05 24.7 0.1 0.073 12.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK26147.1 - 1.2e-05 24.7 0.1 0.0099 15.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 KKK26147.1 - 8.1e-05 22.6 0.0 0.33 11.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK26147.1 - 0.0052 17.3 0.6 3.2 8.6 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK26147.1 - 0.014 15.1 0.1 0.82 9.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK26147.1 - 0.034 14.8 0.1 3.2 8.5 0.0 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK26147.1 - 0.075 13.5 0.1 4.9 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat N1221 PF07923.8 KKK26147.1 - 0.12 11.2 0.1 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 N1221-like protein SNARE PF05739.14 KKK26148.1 - 4.3e-10 39.1 4.5 1.5e-09 37.3 3.1 2.0 1 0 0 1 1 1 1 SNARE domain Dispanin PF04505.7 KKK26148.1 - 0.02 14.4 0.5 0.042 13.3 0.3 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein MCPsignal PF00015.16 KKK26148.1 - 0.03 13.8 10.4 0.051 13.1 5.3 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HisKA_3 PF07730.8 KKK26148.1 - 0.039 14.3 12.3 0.26 11.6 0.0 4.1 4 1 1 5 5 5 0 Histidine kinase DUF2370 PF10176.4 KKK26148.1 - 0.079 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Fusion_gly PF00523.13 KKK26148.1 - 0.13 10.2 2.4 0.12 10.3 0.2 1.9 1 1 1 2 2 2 0 Fusion glycoprotein F0 AAA_13 PF13166.1 KKK26148.1 - 0.21 9.9 7.3 0.35 9.2 5.0 1.4 1 0 0 1 1 1 0 AAA domain Syntaxin_2 PF14523.1 KKK26148.1 - 0.36 10.8 11.2 1.7 8.7 2.4 3.0 2 1 1 3 3 3 0 Syntaxin-like protein Synaptobrevin PF00957.16 KKK26148.1 - 0.48 10.0 3.6 0.2 11.2 0.3 2.1 2 0 0 2 2 2 0 Synaptobrevin CDC37_N PF03234.9 KKK26148.1 - 0.82 9.9 10.4 0.86 9.8 1.7 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF1664 PF07889.7 KKK26148.1 - 1.1 9.0 5.4 1.4 8.6 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2562 PF10814.3 KKK26148.1 - 2.7 7.9 6.5 3.3 7.6 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) HTH_37 PF13744.1 KKK26148.1 - 3 7.7 6.3 1.6 8.6 0.9 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF848 PF05852.6 KKK26148.1 - 3.4 7.5 10.1 2.9 7.7 2.3 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF724 PF05266.9 KKK26148.1 - 5.4 6.6 8.5 3.1 7.3 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Mnd1 PF03962.10 KKK26148.1 - 8.9 5.9 18.0 1.1 8.9 2.2 3.0 1 1 1 3 3 3 0 Mnd1 family Baculo_PEP_C PF04513.7 KKK26148.1 - 9.8 5.9 11.9 3.7 7.3 1.1 3.0 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BolA PF01722.13 KKK26149.1 - 1e-28 99.0 1.8 1.3e-28 98.7 1.2 1.1 1 0 0 1 1 1 1 BolA-like protein DDE_3 PF13358.1 KKK26149.1 - 0.034 13.9 0.1 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease RPA_C PF08784.6 KKK26149.1 - 0.089 13.2 0.1 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal