# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- APH PF01636.23 EEQ27113.1 - 3.7e-12 46.7 0.0 7.7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_3 PF13302.7 EEQ27114.1 - 2.4e-27 96.3 0.0 3e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EEQ27114.1 - 0.047 13.4 0.2 0.092 12.4 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ27114.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family BCNT PF07572.12 EEQ27115.1 - 1.3e-26 92.4 0.2 3.6e-26 91.0 0.2 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development CDC45 PF02724.14 EEQ27115.1 - 9.7 4.3 13.4 13 3.9 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SUR7 PF06687.12 EEQ27116.1 - 2.8 7.5 16.0 13 5.4 0.2 2.9 2 1 0 2 2 2 0 SUR7/PalI family CD20 PF04103.15 EEQ27116.1 - 7.2 6.7 16.5 49 4.0 9.4 3.5 2 1 1 3 3 3 0 CD20-like family Mis12 PF05859.12 EEQ27118.1 - 5.9e-38 130.0 0.0 9.1e-38 129.4 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein MitoNEET_N PF10660.9 EEQ27118.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus APH PF01636.23 EEQ27119.1 - 7e-05 22.9 0.1 0.00019 21.4 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EEQ27119.1 - 0.00083 18.8 0.2 0.0015 17.9 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EEQ27119.1 - 0.0011 18.5 0.1 0.0027 17.3 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase HSDR_N_2 PF13588.6 EEQ27119.1 - 0.0026 17.7 0.0 3.2 7.8 0.0 2.8 3 0 0 3 3 3 2 Type I restriction enzyme R protein N terminus (HSDR_N) Kdo PF06293.14 EEQ27119.1 - 0.017 14.5 0.2 0.031 13.6 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CENP-X PF09415.10 EEQ27120.1 - 1.9e-24 85.7 0.5 4.1e-24 84.7 0.5 1.6 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 EEQ27120.1 - 0.26 11.6 0.2 0.26 11.6 0.2 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PknG_rubred PF16919.5 EEQ27120.1 - 1 9.5 5.6 1.9 8.6 4.7 1.8 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain Presenilin PF01080.17 EEQ27120.1 - 5.5 5.7 6.6 5.6 5.6 6.6 1.2 1 0 0 1 1 1 0 Presenilin Macro PF01661.21 EEQ27121.1 - 0.031 14.3 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Macro domain MIF PF01187.18 EEQ27122.1 - 0.035 14.4 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Dus PF01207.17 EEQ27123.1 - 2.6e-35 122.0 0.0 1.5e-31 109.7 0.0 2.5 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) Imm39 PF15568.6 EEQ27123.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 39 bZIP_1 PF00170.21 EEQ27124.1 - 7.2e-09 35.6 8.0 7.2e-09 35.6 8.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EEQ27124.1 - 0.00046 20.2 9.9 0.00046 20.2 9.9 2.9 3 0 0 3 3 3 1 Basic region leucine zipper Methyltransf_25 PF13649.6 EEQ27125.1 - 1.9e-20 73.4 0.0 2.7e-18 66.5 0.0 3.2 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27125.1 - 5.2e-20 71.9 0.0 1.6e-15 57.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ27125.1 - 1.9e-16 60.4 0.0 1.1e-14 54.6 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27125.1 - 3.1e-15 56.3 0.0 7.5e-13 48.5 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ27125.1 - 1e-13 51.8 0.0 1.6e-09 38.4 0.0 2.7 3 0 0 3 3 2 2 Methyltransferase domain CMAS PF02353.20 EEQ27125.1 - 1.2e-10 41.2 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 EEQ27125.1 - 7.8e-05 22.2 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Pox_MCEL PF03291.16 EEQ27125.1 - 0.00028 20.1 0.0 0.0059 15.8 0.0 2.2 1 1 0 1 1 1 1 mRNA capping enzyme MetW PF07021.12 EEQ27125.1 - 0.0003 20.4 0.0 0.008 15.8 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW CheR PF01739.18 EEQ27125.1 - 0.0033 16.9 0.1 0.27 10.7 0.0 2.4 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 EEQ27125.1 - 0.0042 16.5 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EEQ27125.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EEQ27125.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain TPMT PF05724.11 EEQ27125.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 EEQ27125.1 - 0.017 14.6 0.0 0.054 13.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 EEQ27125.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 EEQ27125.1 - 0.026 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase UPF0146 PF03686.13 EEQ27125.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_32 PF13679.6 EEQ27125.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 EEQ27125.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cons_hypoth95 PF03602.15 EEQ27125.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pterin_bind PF00809.22 EEQ27125.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Pterin binding enzyme NAD_binding_10 PF13460.6 EEQ27126.1 - 2.9e-20 72.9 0.2 4.2e-20 72.4 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EEQ27126.1 - 0.05 13.1 0.0 0.064 12.7 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B_4 PF13691.6 EEQ27127.1 - 6.4e-28 96.2 0.3 1.9e-26 91.5 0.1 2.9 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EEQ27127.1 - 2.8e-14 53.1 0.6 5.9e-06 25.9 0.1 2.5 1 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EEQ27127.1 - 0.00025 21.1 0.4 0.00072 19.6 0.4 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily His_Phos_2 PF00328.22 EEQ27128.1 - 5.5e-13 49.0 0.0 1.2e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Gtr1_RagA PF04670.12 EEQ27129.1 - 1e-51 175.6 0.5 1.8e-51 174.8 0.5 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EEQ27129.1 - 0.037 13.8 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.21 EEQ27129.1 - 0.043 13.3 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family Cyt-b5 PF00173.28 EEQ27130.1 - 5.1e-10 39.4 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S25 PF03297.15 EEQ27131.1 - 8.7e-39 131.8 4.7 9.5e-39 131.7 4.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 EEQ27131.1 - 0.0082 15.9 0.1 0.011 15.4 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EEQ27131.1 - 0.016 15.1 0.1 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 EEQ27131.1 - 0.03 14.2 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 EEQ27131.1 - 0.039 14.3 0.1 0.052 13.9 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator GntR PF00392.21 EEQ27131.1 - 0.086 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EEQ27131.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ANAPC4_WD40 PF12894.7 EEQ27132.1 - 2.2e-09 37.5 0.3 0.00092 19.5 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ27132.1 - 4.5e-06 27.3 6.5 0.027 15.4 0.1 4.9 4 2 2 6 6 6 2 WD domain, G-beta repeat IKI3 PF04762.12 EEQ27132.1 - 0.00029 19.0 0.0 0.00051 18.2 0.0 1.3 1 0 0 1 1 1 1 IKI3 family PD40 PF07676.12 EEQ27132.1 - 0.0082 16.1 0.3 1.1 9.3 0.1 3.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Arg_repressor_C PF02863.18 EEQ27132.1 - 0.13 12.1 0.0 0.89 9.5 0.0 2.2 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 EEQ27133.1 - 2.8e-08 34.5 0.0 5.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.27 EEQ27134.1 - 8.6e-08 32.8 0.0 1.6e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EEQ27134.1 - 0.00028 20.8 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ27134.1 - 0.00033 20.3 0.0 0.00069 19.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EEQ27134.1 - 0.0076 16.8 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EEQ27134.1 - 0.0085 16.2 0.0 0.02 15.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EEQ27134.1 - 0.024 14.9 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EEQ27134.1 - 0.033 13.8 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ27134.1 - 0.046 13.7 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 EEQ27134.1 - 0.073 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EEQ27134.1 - 0.075 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EEQ27134.1 - 0.085 12.0 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EEQ27134.1 - 0.093 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEQ27134.1 - 0.1 13.0 0.2 0.14 12.6 0.2 1.3 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 EEQ27134.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Adeno_IVa2 PF02456.15 EEQ27134.1 - 0.14 10.9 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.18 EEQ27134.1 - 0.17 11.2 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EEQ27134.1 - 0.17 11.4 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 EEQ27134.1 - 0.17 12.0 0.2 0.2 11.7 0.2 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 EEQ27135.1 - 4.8e-24 85.4 0.0 8.2e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EEQ27135.1 - 6.8e-06 26.1 2.5 0.046 13.5 0.3 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ27135.1 - 3.2e-05 23.5 0.1 0.017 14.6 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EEQ27135.1 - 0.018 15.1 0.1 0.042 13.9 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ27135.1 - 0.046 13.6 0.1 0.085 12.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_14 PF13173.6 EEQ27135.1 - 0.1 12.6 0.1 1.7 8.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EEQ27135.1 - 0.34 10.7 1.3 0.44 10.3 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AA_permease PF00324.21 EEQ27136.1 - 4.8e-142 473.9 38.5 5.9e-142 473.6 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ27136.1 - 4.9e-36 124.5 39.4 6.1e-36 124.2 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease MoaC PF01967.21 EEQ27137.1 - 3.4e-44 150.2 0.2 5.5e-44 149.6 0.2 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EEQ27137.1 - 5.8e-37 126.5 0.0 5.6e-36 123.3 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EEQ27137.1 - 1.8e-28 100.0 0.1 3.9e-28 98.9 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EEQ27137.1 - 9e-05 22.8 0.0 0.00025 21.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain CARMIL_C PF16000.5 EEQ27137.1 - 2.4 7.7 5.4 0.17 11.5 0.4 1.5 2 0 0 2 2 2 0 CARMIL C-terminus Piwi PF02171.17 EEQ27138.1 - 1.2e-19 70.7 0.2 1.6e-10 40.7 0.1 2.2 1 1 1 2 2 2 2 Piwi domain ArgoL2 PF16488.5 EEQ27138.1 - 4.9e-05 23.6 0.3 0.00018 21.8 0.1 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoN PF16486.5 EEQ27138.1 - 0.005 17.5 0.1 0.01 16.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 EEQ27138.1 - 0.0056 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 PAZ domain bMG10 PF17973.1 EEQ27139.1 - 0.042 14.0 0.4 0.1 12.8 0.4 1.7 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain VPS28 PF03997.12 EEQ27140.1 - 1.2e-73 246.8 0.6 1.4e-73 246.6 0.6 1.0 1 0 0 1 1 1 1 VPS28 protein SPOB_a PF14689.6 EEQ27140.1 - 0.031 14.0 0.9 0.072 12.8 0.1 1.9 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain Methyltransf_16 PF10294.9 EEQ27141.1 - 2.2e-20 73.1 0.0 5e-20 71.9 0.0 1.5 2 0 0 2 2 2 1 Lysine methyltransferase APH PF01636.23 EEQ27142.1 - 3.2e-16 60.0 0.0 4.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ27142.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MFS_1 PF07690.16 EEQ27144.1 - 1.4e-30 106.4 92.8 3.8e-29 101.7 60.1 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EEQ27144.1 - 3.4e-15 55.5 13.2 3.4e-15 55.5 13.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ27144.1 - 6.2e-12 45.1 5.4 6.2e-12 45.1 5.4 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 EEQ27145.1 - 1.6e-14 53.9 0.0 1.1e-07 31.5 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27145.1 - 3.1e-09 36.5 0.0 0.00012 21.5 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Tannase PF07519.11 EEQ27147.1 - 2.4e-76 257.6 0.1 1.6e-71 241.6 0.0 2.1 1 1 1 2 2 2 2 Tannase and feruloyl esterase Zn_clus PF00172.18 EEQ27147.1 - 1.4e-08 34.7 8.4 2.7e-08 33.8 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 EEQ27147.1 - 0.02 14.5 0.1 0.072 12.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold VWA PF00092.28 EEQ27148.1 - 2.2e-06 28.0 0.0 3.9e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EEQ27148.1 - 0.0016 19.1 0.0 0.0045 17.6 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain ANAPC4 PF12896.7 EEQ27150.1 - 3.4e-63 212.8 0.6 4.8e-63 212.3 0.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EEQ27150.1 - 7.2e-31 106.3 0.0 4.5e-30 103.8 0.0 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF374 PF04028.13 EEQ27150.1 - 0.085 12.4 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF374) HEAT PF02985.22 EEQ27151.1 - 2e-15 55.5 15.1 0.00013 22.0 0.0 9.8 12 0 0 12 12 11 2 HEAT repeat HEAT_EZ PF13513.6 EEQ27151.1 - 2.1e-11 44.1 6.6 1.5e-06 28.5 0.0 7.6 7 1 0 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 EEQ27151.1 - 2e-09 37.7 10.9 0.00033 21.0 0.1 7.1 4 2 4 8 8 8 4 HEAT repeats CLASP_N PF12348.8 EEQ27151.1 - 2.3e-07 30.6 1.6 0.011 15.4 0.0 4.4 4 1 0 4 4 4 2 CLASP N terminal IBN_N PF03810.19 EEQ27151.1 - 7.9e-07 28.9 1.5 0.0011 18.9 0.1 4.2 3 1 0 3 3 3 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EEQ27151.1 - 0.00092 19.2 4.5 3.4 7.5 0.0 4.4 5 1 0 5 5 5 2 Domain of unknown function (DUF3385) MMS19_N PF14500.6 EEQ27151.1 - 0.0044 16.6 1.4 1.3 8.6 0.7 3.4 2 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Cse1 PF08506.10 EEQ27151.1 - 0.012 14.5 0.0 1.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Cse1 Arm PF00514.23 EEQ27151.1 - 0.017 15.1 5.6 27 5.0 0.2 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 EEQ27151.1 - 0.05 13.5 0.5 2.6 7.9 0.0 3.3 2 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Uso1_p115_head PF04869.14 EEQ27151.1 - 0.33 10.0 5.8 0.34 10.0 0.3 2.8 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, head region NUC173 PF08161.12 EEQ27151.1 - 0.35 10.5 3.3 71 3.0 0.0 4.1 4 1 0 5 5 5 0 NUC173 domain Ribosomal_S8 PF00410.19 EEQ27152.1 - 4.8e-22 78.3 0.1 7.4e-22 77.6 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.22 EEQ27153.1 - 2.1e-12 47.2 0.0 3.7e-11 43.1 0.0 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ubiquitin PF00240.23 EEQ27154.1 - 1.1e-10 41.1 0.0 2.3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EEQ27154.1 - 0.00057 20.4 1.3 0.0009 19.8 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEQ27154.1 - 0.0062 16.6 0.0 0.029 14.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PS_Dcarbxylase PF02666.15 EEQ27155.1 - 6.9e-76 254.3 0.0 2e-75 252.7 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase E1-E2_ATPase PF00122.20 EEQ27156.1 - 1.3e-36 125.8 9.3 4.9e-29 101.1 0.3 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EEQ27156.1 - 1.2e-28 100.0 9.4 1e-27 97.1 5.9 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EEQ27156.1 - 3.9e-19 69.8 0.9 8.8e-16 58.8 0.9 3.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ27156.1 - 4.9e-15 55.4 0.0 1.1e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EEQ27156.1 - 9.3e-12 44.5 0.0 1.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEQ27156.1 - 4.2e-05 23.4 0.1 0.0043 16.8 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EEQ27156.1 - 0.0075 16.2 0.6 0.014 15.3 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) ANAPC10 PF03256.16 EEQ27157.1 - 2.3e-44 151.2 0.0 3.5e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DNA_pol_phi PF04931.13 EEQ27157.1 - 0.3 9.1 6.7 0.044 11.9 1.8 1.8 2 0 0 2 2 2 0 DNA polymerase phi FAM176 PF14851.6 EEQ27157.1 - 1.2 8.7 4.5 1.9 8.2 0.8 2.4 2 0 0 2 2 2 0 FAM176 family TFIIA PF03153.13 EEQ27157.1 - 2.7 7.9 8.6 3.6 7.5 3.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Iso_dh PF00180.20 EEQ27158.1 - 5.6e-128 427.0 0.0 6.3e-128 426.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.25 EEQ27159.1 - 1.1e-26 93.8 0.0 6.8e-26 91.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27159.1 - 2.5e-13 49.9 0.1 5.7e-13 48.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EEQ27159.1 - 0.047 13.0 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_23 PF13489.6 EEQ27161.1 - 3.7e-12 46.4 0.0 6.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27161.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ27161.1 - 0.024 15.3 0.0 0.059 14.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27161.1 - 0.025 15.2 0.0 0.056 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ27161.1 - 0.043 14.6 0.0 0.22 12.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Sterol_MT_C PF08498.10 EEQ27161.1 - 0.071 13.4 0.1 0.2 12.0 0.1 1.8 1 1 0 1 1 1 0 Sterol methyltransferase C-terminal CDP-OH_P_transf PF01066.21 EEQ27162.1 - 9.9e-13 48.7 0.4 9.9e-13 48.7 0.4 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.21 EEQ27163.1 - 1.9e-31 109.6 0.0 2.2e-25 89.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EEQ27163.1 - 0.02 14.6 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C DUF4407 PF14362.6 EEQ27164.1 - 0.19 11.1 0.4 0.36 10.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TRAF_BIRC3_bd PF16673.5 EEQ27164.1 - 0.39 10.5 2.2 0.47 10.3 0.9 1.8 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain GrpE PF01025.19 EEQ27164.1 - 1.5 8.5 3.8 1.9 8.1 0.1 2.2 1 1 1 2 2 2 0 GrpE BST2 PF16716.5 EEQ27164.1 - 9.4 6.9 8.3 13 6.5 0.3 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 RRM_1 PF00076.22 EEQ27165.1 - 9.3e-41 137.5 0.4 1.7e-18 66.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EEQ27165.1 - 3.9e-26 92.0 0.6 5.4e-24 85.1 0.2 2.9 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EEQ27165.1 - 0.00078 19.2 0.0 1 9.2 0.0 2.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EEQ27165.1 - 0.061 13.4 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 EEQ27165.1 - 0.07 13.3 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 EEQ27165.1 - 0.078 13.2 0.1 5.9 7.1 0.1 2.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MFS_1 PF07690.16 EEQ27166.1 - 4.7e-34 117.8 42.5 1.1e-32 113.4 41.6 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EEQ27166.1 - 0.0053 15.1 9.3 0.025 12.9 2.3 3.1 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2721 PF11026.8 EEQ27166.1 - 0.033 14.1 0.9 0.033 14.1 0.9 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF2721) DUF2561 PF10812.8 EEQ27166.1 - 0.08 13.0 0.0 0.08 13.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) Cyt-b5 PF00173.28 EEQ27168.1 - 2.1e-18 66.2 0.1 2.1e-18 66.2 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EEQ27168.1 - 2.6e-12 47.2 15.6 2.6e-12 47.2 15.6 1.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EEQ27168.1 - 0.0046 17.2 0.3 0.0099 16.1 0.3 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region OMPdecase PF00215.24 EEQ27169.1 - 1.4e-07 31.4 0.0 2.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Cu-oxidase_2 PF07731.14 EEQ27170.1 - 5.1e-48 162.3 7.1 5.5e-43 146.0 0.5 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EEQ27170.1 - 1.7e-42 144.2 3.7 1.8e-39 134.4 0.8 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EEQ27170.1 - 6.9e-36 123.8 0.2 3.8e-31 108.4 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EEQ27170.1 - 0.00097 19.2 0.0 4.2 7.5 0.0 3.4 2 1 0 2 2 2 2 Cupredoxin-like domain FTR1 PF03239.14 EEQ27171.1 - 4.8e-67 226.3 5.7 6.4e-67 225.9 5.7 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family Rft-1 PF04506.13 EEQ27171.1 - 0.024 13.4 0.6 0.037 12.8 0.6 1.2 1 0 0 1 1 1 0 Rft protein FtsX PF02687.21 EEQ27171.1 - 0.072 13.6 0.9 0.072 13.6 0.9 3.2 3 1 0 3 3 3 0 FtsX-like permease family ABC2_membrane_3 PF12698.7 EEQ27171.1 - 0.59 9.2 7.4 0.55 9.3 0.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4229 PF14012.6 EEQ27171.1 - 1.2 9.3 5.2 3 8.0 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Adap_comp_sub PF00928.21 EEQ27173.1 - 1e-20 74.2 0.0 1.4e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EEQ27173.1 - 1.3e-07 31.7 0.1 2e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 EEQ27173.1 - 0.0028 18.0 0.2 0.0055 17.1 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.9 EEQ27174.1 - 6.3e-06 26.2 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.14 EEQ27175.1 - 1.5e-100 336.1 13.2 1.7e-100 335.9 13.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EEQ27175.1 - 3.4e-06 27.3 26.7 3.7e-05 23.9 8.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family Acyl_transf_3 PF01757.22 EEQ27175.1 - 0.041 13.0 18.0 0.028 13.5 7.6 2.1 1 1 1 2 2 2 0 Acyltransferase family DUF4293 PF14126.6 EEQ27175.1 - 1.7 8.9 5.3 3 8.1 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Syja_N PF02383.18 EEQ27176.1 - 8.7e-79 265.1 0.0 2.8e-60 204.3 0.0 2.3 1 1 1 2 2 2 2 SacI homology domain hSac2 PF12456.8 EEQ27176.1 - 3e-39 133.3 0.0 5.3e-39 132.5 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase HEAT_EZ PF13513.6 EEQ27177.1 - 2.7e-29 101.2 13.0 1.4e-15 57.4 0.0 10.3 7 3 4 11 11 11 4 HEAT-like repeat HEAT PF02985.22 EEQ27177.1 - 2.3e-24 83.3 9.9 7.4e-05 22.7 0.0 10.9 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.6 EEQ27177.1 - 1.3e-19 70.3 0.9 1.9e-05 25.0 0.0 8.1 5 3 3 8 8 8 3 HEAT repeats Cnd1 PF12717.7 EEQ27177.1 - 1.3e-12 48.1 0.2 0.0016 18.5 0.0 5.8 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EEQ27177.1 - 7e-09 36.2 0.0 0.03 14.9 0.0 4.7 4 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EEQ27177.1 - 1.3e-08 34.4 6.8 0.31 10.1 1.1 5.3 5 0 0 5 5 5 3 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 EEQ27177.1 - 1.6e-07 31.1 1.3 0.001 18.7 0.1 5.7 3 3 1 4 4 4 1 CLASP N terminal Xpo1 PF08389.12 EEQ27177.1 - 0.00024 21.2 1.2 0.0058 16.7 0.0 3.8 5 1 0 5 5 3 1 Exportin 1-like protein DUF3437 PF11919.8 EEQ27177.1 - 0.00027 20.8 0.5 0.15 12.0 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) DRIM PF07539.12 EEQ27177.1 - 0.00036 19.0 0.0 0.1 10.9 0.1 3.5 3 1 0 3 3 3 1 Down-regulated in metastasis RIX1 PF08167.12 EEQ27177.1 - 0.00051 19.8 0.8 15 5.3 0.1 5.5 6 1 1 7 7 7 0 rRNA processing/ribosome biogenesis IBN_N PF03810.19 EEQ27177.1 - 0.00091 19.1 0.8 0.042 13.8 0.0 4.0 3 2 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EEQ27177.1 - 0.0012 17.5 1.1 0.67 8.4 0.0 4.2 4 2 1 5 5 5 1 Adaptin N terminal region Sec7_N PF12783.7 EEQ27177.1 - 0.0012 18.8 0.5 0.0046 16.9 0.2 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Dopey_N PF04118.14 EEQ27177.1 - 0.0032 16.6 0.1 0.16 11.0 0.0 2.7 2 1 0 2 2 2 1 Dopey, N-terminal Arm PF00514.23 EEQ27177.1 - 0.0034 17.4 4.8 2.1 8.5 0.0 5.9 7 0 0 7 7 5 1 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 EEQ27177.1 - 0.0055 16.5 0.6 3 7.6 0.0 3.6 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) RTP1_C1 PF10363.9 EEQ27177.1 - 0.0072 16.5 0.0 0.033 14.4 0.0 2.2 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 EEQ27177.1 - 0.16 12.1 0.1 0.65 10.1 0.1 2.0 1 0 0 1 1 1 0 V-ATPase subunit H HEAT_PBS PF03130.16 EEQ27177.1 - 0.8 10.5 5.8 27 5.8 0.0 5.0 7 0 0 7 7 2 0 PBS lyase HEAT-like repeat Fungal_trans_2 PF11951.8 EEQ27179.1 - 2.3e-09 36.6 1.2 3.8e-09 35.8 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ27179.1 - 3.8e-07 30.1 15.5 7.1e-07 29.2 15.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C12 PF01088.21 EEQ27180.1 - 1.7e-68 230.5 0.0 2.2e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EEQ27180.1 - 1e-07 31.7 0.0 2.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases DUF1556 PF07590.11 EEQ27182.1 - 0.22 11.9 0.5 0.41 11.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) MFS_1 PF07690.16 EEQ27183.1 - 2.3e-30 105.7 29.2 3.5e-30 105.1 28.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Neurensin PF14927.6 EEQ27183.1 - 1.1 8.9 5.7 3.7 7.3 0.3 3.0 3 0 0 3 3 3 0 Neurensin DUF1656 PF07869.12 EEQ27183.1 - 4.5 7.4 8.6 1.5 8.9 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Amidohydro_2 PF04909.14 EEQ27185.1 - 1.3e-13 51.4 0.2 1.3e-12 48.1 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase CitT PF12431.8 EEQ27185.1 - 0.13 12.7 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator Fungal_trans PF04082.18 EEQ27186.1 - 5.4e-26 91.2 0.1 1.3e-25 90.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ27186.1 - 2.2e-09 37.3 9.4 4.2e-09 36.4 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 EEQ27186.1 - 0.04 13.9 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension JHY PF15261.6 EEQ27186.1 - 0.14 12.9 0.6 0.3 11.8 0.6 1.5 1 0 0 1 1 1 0 Jhy protein SOGA PF11365.8 EEQ27186.1 - 0.16 13.1 0.2 0.45 11.7 0.2 1.6 2 0 0 2 2 2 0 Protein SOGA Opy2 PF09463.10 EEQ27186.1 - 0.85 10.0 6.2 0.23 11.8 1.6 2.2 2 0 0 2 2 2 0 Opy2 protein tRNA-synt_2b PF00587.25 EEQ27187.1 - 5e-33 114.6 0.0 8.5e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EEQ27187.1 - 2.8e-05 24.2 0.0 0.00023 21.2 0.0 2.4 3 0 0 3 3 3 1 Anticodon binding domain Maf1 PF09174.10 EEQ27187.1 - 0.22 11.7 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Maf1 regulator ECH_1 PF00378.20 EEQ27188.1 - 1.7e-39 135.6 0.0 2.2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EEQ27188.1 - 2.4e-25 89.8 0.2 4.5e-25 88.8 0.2 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DNase-RNase PF02577.14 EEQ27188.1 - 0.17 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Bifunctional nuclease Pyr_redox_2 PF07992.14 EEQ27189.1 - 1.4e-54 185.4 0.5 2.4e-54 184.6 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EEQ27189.1 - 2.3e-31 108.3 0.1 5e-31 107.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EEQ27189.1 - 2.3e-13 50.5 0.1 2.3e-13 50.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ27189.1 - 5.8e-11 42.2 1.0 8.6e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EEQ27189.1 - 0.042 13.7 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 EEQ27189.1 - 0.048 12.8 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EEQ27189.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EEQ27189.1 - 0.64 9.0 3.6 0.74 8.8 0.5 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Ank_2 PF12796.7 EEQ27191.1 - 0.00025 21.6 0.0 0.00049 20.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ27191.1 - 0.00044 20.8 0.0 0.00099 19.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ27191.1 - 0.0058 17.0 0.0 0.17 12.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EEQ27191.1 - 0.033 14.6 0.0 0.6 10.7 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat CDC45 PF02724.14 EEQ27191.1 - 0.036 12.4 3.0 0.04 12.2 3.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Ank_5 PF13857.6 EEQ27191.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Paf1 PF03985.13 EEQ27191.1 - 0.081 11.9 3.1 0.1 11.6 3.1 1.1 1 0 0 1 1 1 0 Paf1 YL1 PF05764.13 EEQ27191.1 - 0.28 11.3 11.8 0.43 10.7 11.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PTPRCAP PF15713.5 EEQ27191.1 - 1.2 9.4 10.5 2.6 8.3 10.5 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 EEQ27191.1 - 1.6 8.1 8.2 2.2 7.6 8.2 1.2 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 EEQ27191.1 - 2 6.9 4.1 2.3 6.7 4.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EEQ27191.1 - 2.2 6.4 10.6 2.8 6.0 10.6 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EEQ27191.1 - 2.7 7.2 8.6 3.5 6.9 8.6 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EEQ27191.1 - 5.6 4.9 18.6 7.5 4.5 18.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 EEQ27191.1 - 6.8 7.1 10.8 18 5.8 10.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop53 PF07767.11 EEQ27191.1 - 9.6 5.5 8.6 14 5.0 8.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MFS_1 PF07690.16 EEQ27192.1 - 7.7e-46 156.6 39.6 1.5e-45 155.6 39.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ27192.1 - 9.6e-16 57.3 14.7 9.6e-16 57.3 14.7 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ27192.1 - 2.4e-15 56.4 13.3 2.4e-15 56.4 13.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Peptidase_C37 PF05416.12 EEQ27192.1 - 0.26 9.8 0.4 0.57 8.6 0.1 1.6 2 0 0 2 2 2 0 Southampton virus-type processing peptidase DUF3419 PF11899.8 EEQ27194.1 - 6.5e-158 525.9 0.1 9.7e-158 525.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EEQ27194.1 - 1.1e-09 38.3 0.0 6.2e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ27194.1 - 9.4e-09 35.9 0.0 1.1e-07 32.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27194.1 - 3.5e-06 27.6 0.0 5.8e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27194.1 - 4.8e-06 26.5 0.0 1.5e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ27194.1 - 6.8e-06 26.8 0.0 2.9e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EEQ27194.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EEQ27194.1 - 0.0012 18.3 0.0 0.003 16.9 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EEQ27194.1 - 0.0038 16.7 0.0 0.044 13.3 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase AP_endonuc_2 PF01261.24 EEQ27195.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Vps54 PF07928.12 EEQ27196.1 - 4.5e-28 98.3 0.2 2e-27 96.2 0.1 2.2 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 EEQ27196.1 - 0.00026 20.4 0.6 0.0006 19.2 0.1 1.8 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex RINT1_TIP1 PF04437.13 EEQ27196.1 - 0.0023 16.9 0.0 0.36 9.7 0.0 2.3 2 0 0 2 2 2 2 RINT-1 / TIP-1 family COG2 PF06148.11 EEQ27196.1 - 0.053 13.6 0.3 0.42 10.7 0.1 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3490 PF11995.8 EEQ27196.1 - 0.66 9.8 3.3 0.41 10.4 0.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3490) Solute_trans_a PF03619.16 EEQ27197.1 - 2.2e-61 207.7 10.1 2.9e-61 207.3 10.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha YycC PF14174.6 EEQ27197.1 - 0.18 11.6 0.9 0.27 11.1 0.3 1.7 2 0 0 2 2 2 0 YycC-like protein Pkinase PF00069.25 EEQ27199.1 - 2.7e-54 184.3 0.0 5.2e-52 176.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27199.1 - 7.7e-32 110.6 0.0 7.6e-31 107.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EEQ27199.1 - 0.0015 17.6 0.1 0.0027 16.8 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EEQ27199.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEQ27199.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EEQ27199.1 - 0.072 11.9 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase AJAP1_PANP_C PF15298.6 EEQ27199.1 - 3.6 7.8 12.2 6.9 6.8 12.2 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus APH PF01636.23 EEQ27200.1 - 1.1e-08 35.3 0.0 5.7e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Mem_trans PF03547.18 EEQ27201.1 - 8.6e-52 175.8 2.1 1e-51 175.5 2.1 1.1 1 0 0 1 1 1 1 Membrane transport protein Choline_kinase PF01633.20 EEQ27202.1 - 5.1e-36 124.3 0.0 9.6e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EEQ27202.1 - 5.7e-16 57.9 0.0 1.4e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus Abhydrolase_2 PF02230.16 EEQ27203.1 - 2.6e-23 83.0 0.0 2.1e-16 60.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EEQ27203.1 - 0.0013 18.2 0.2 0.0028 17.2 0.2 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EEQ27203.1 - 0.0064 15.8 0.1 0.021 14.1 0.0 2.0 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EEQ27203.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Glyco_hydro_31 PF01055.26 EEQ27204.1 - 3.6e-168 560.3 1.3 4.5e-168 560.0 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EEQ27204.1 - 6.5e-38 129.5 0.1 2.1e-37 127.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EEQ27204.1 - 1.6e-15 57.1 0.3 6.4e-15 55.2 0.3 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EEQ27204.1 - 0.0065 16.7 0.1 0.017 15.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) ANAPC15 PF15243.6 EEQ27205.1 - 0.022 15.2 3.1 0.022 15.2 3.1 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Asp PF00026.23 EEQ27206.1 - 9.8e-08 31.8 0.8 2.5e-06 27.2 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease EphA2_TM PF14575.6 EEQ27206.1 - 0.029 15.3 0.0 0.05 14.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 EEQ27206.1 - 0.042 13.3 0.1 0.082 12.3 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MFS_1 PF07690.16 EEQ27207.1 - 1.7e-17 63.4 40.1 1.2e-12 47.5 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ27207.1 - 6.2e-14 51.7 23.2 5.5e-13 48.6 23.2 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_92 PF07971.12 EEQ27208.1 - 1.1e-127 426.8 0.3 3.8e-125 418.4 0.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EEQ27208.1 - 5.6e-41 141.0 3.4 6.6e-41 140.8 2.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain M157 PF11624.8 EEQ27208.1 - 0.082 12.2 0.2 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 ATP-synt_G PF04718.15 EEQ27210.1 - 1.7e-34 118.6 0.0 6.9e-34 116.7 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_zinc_N PF00107.26 EEQ27211.1 - 3.1e-18 66.0 0.0 7.6e-18 64.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ27211.1 - 1e-15 59.0 0.0 3.2e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ27211.1 - 1.6e-06 28.0 0.1 1.1e-05 25.2 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain APH PF01636.23 EEQ27212.1 - 7.9e-12 45.6 0.0 9.6e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ27212.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase HECA PF15353.6 EEQ27212.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Headcase protein family homologue RIO1 PF01163.22 EEQ27212.1 - 0.013 15.1 0.1 0.032 13.8 0.0 1.7 1 1 1 2 2 2 0 RIO1 family Kdo PF06293.14 EEQ27212.1 - 0.063 12.6 0.1 3.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_1 PF00561.20 EEQ27213.1 - 4.6e-14 52.7 0.0 3.4e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ27213.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ27213.1 - 0.095 13.3 0.0 0.13 12.8 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAP_central PF04928.17 EEQ27214.1 - 4.2e-108 360.0 0.0 5.6e-108 359.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EEQ27214.1 - 2.1e-58 196.7 0.0 3.3e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EEQ27214.1 - 4.4e-06 26.9 0.4 0.0027 18.0 0.0 2.5 2 0 0 2 2 2 2 Nucleotidyltransferase domain Nrap_D2 PF17403.2 EEQ27214.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Glyco_transf_20 PF00982.21 EEQ27215.1 - 2.9e-153 511.0 0.0 3.7e-152 507.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 EEQ27215.1 - 0.00045 19.8 0.1 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEQ27215.1 - 0.0012 19.3 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EEQ27215.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 EEQ27215.1 - 0.083 13.3 0.1 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 adh_short_C2 PF13561.6 EEQ27216.1 - 4.8e-42 144.1 3.6 5.9e-42 143.8 3.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ27216.1 - 3.8e-39 134.2 0.7 4.6e-39 133.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ27216.1 - 3.8e-11 43.2 0.5 6e-11 42.6 0.5 1.3 1 0 0 1 1 1 1 KR domain Amidase PF01425.21 EEQ27217.1 - 2.6e-84 283.8 0.0 3.2e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Cation_efflux PF01545.21 EEQ27218.1 - 3.3e-14 53.1 6.6 4.1e-14 52.8 6.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EEQ27218.1 - 1.2e-10 41.4 0.2 2.9e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF1640 PF07798.11 EEQ27218.1 - 0.012 15.6 0.8 0.025 14.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Sulfotransfer_4 PF17784.1 EEQ27219.1 - 1.3e-54 185.3 0.0 1.6e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EEQ27219.1 - 0.00082 19.8 0.1 0.069 13.5 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family 2_5_RNA_ligase2 PF13563.6 EEQ27220.1 - 1.2e-30 106.4 0.0 2.8e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 EEQ27220.1 - 1.4e-21 76.6 0.0 2.5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 EEQ27220.1 - 1.6e-20 73.6 0.7 4.6e-20 72.1 0.7 1.9 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos PF03372.23 EEQ27220.1 - 5.8e-08 32.5 0.0 1.9e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 EEQ27220.1 - 1.4e-05 25.3 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EEQ27220.1 - 0.0024 18.0 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase LigT_PEase PF02834.16 EEQ27220.1 - 0.0061 16.7 0.0 0.037 14.2 0.0 2.3 2 0 0 2 2 2 1 LigT like Phosphoesterase NPL PF17800.1 EEQ27220.1 - 0.14 12.7 0.0 24 5.6 0.0 2.9 3 0 0 3 3 3 0 Nucleoplasmin-like domain HydF_tetramer PF18133.1 EEQ27220.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain GATA PF00320.27 EEQ27224.1 - 3.1e-15 55.5 5.3 6.3e-15 54.5 5.3 1.6 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 EEQ27224.1 - 0.38 11.0 1.6 0.92 9.8 1.6 1.6 1 0 0 1 1 1 0 zinc-ribbon Macro PF01661.21 EEQ27225.1 - 3.4e-35 120.6 0.0 6.1e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain Ank_2 PF12796.7 EEQ27226.1 - 2.5e-06 28.0 0.0 3.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ27226.1 - 0.00016 22.2 0.2 0.00063 20.2 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EEQ27226.1 - 0.0011 19.3 0.2 0.67 10.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EEQ27226.1 - 0.0029 18.0 0.1 2.9 8.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat HTH_7 PF02796.15 EEQ27226.1 - 0.056 13.5 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Ank_5 PF13857.6 EEQ27226.1 - 0.076 13.4 0.3 1.1 9.7 0.1 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Peptidase_S24 PF00717.23 EEQ27227.1 - 0.00041 20.2 0.0 0.0019 18.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EEQ27227.1 - 0.13 12.1 0.0 3.3 7.5 0.0 2.4 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 PH PF00169.29 EEQ27228.1 - 0.0084 16.6 0.2 3.6 8.1 0.0 3.3 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 EEQ27228.1 - 0.52 10.8 2.3 15 6.1 0.1 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain GLTP PF08718.11 EEQ27229.1 - 4.7e-40 137.3 0.1 7.5e-40 136.6 0.1 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF4554 PF15091.6 EEQ27229.1 - 0.067 12.1 0.5 0.1 11.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) AA_permease_2 PF13520.6 EEQ27230.1 - 4.8e-62 210.2 50.9 6e-62 209.9 50.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ27230.1 - 3.1e-19 68.9 39.3 4.3e-19 68.5 39.3 1.2 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 EEQ27230.1 - 5.4 7.1 0.0 5.4 7.1 0.0 3.7 4 0 0 4 4 4 0 LPXTG cell wall anchor motif E1-E2_ATPase PF00122.20 EEQ27232.1 - 2.9e-20 72.5 0.0 7.7e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EEQ27232.1 - 7.9e-14 52.4 1.5 8.3e-07 29.5 2.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEQ27232.1 - 0.0043 16.8 0.2 0.028 14.1 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ27232.1 - 0.0056 16.7 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) S6PP PF05116.13 EEQ27232.1 - 0.01 15.4 0.4 0.28 10.7 0.0 2.6 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase FYVE PF01363.21 EEQ27233.1 - 5e-23 81.0 23.9 4.4e-17 62.0 5.1 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EEQ27233.1 - 1.3e-17 63.2 0.6 3.4e-17 61.9 0.6 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 EEQ27233.1 - 0.0038 17.5 10.0 0.099 13.0 0.0 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 EEQ27233.1 - 0.008 16.3 6.0 0.008 16.3 6.0 3.7 3 1 1 4 4 4 1 AN1-like Zinc finger YqaH PF17448.2 EEQ27233.1 - 0.016 15.5 0.2 0.039 14.3 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized YqaH-like TMF_TATA_bd PF12325.8 EEQ27233.1 - 0.022 15.0 2.2 0.044 14.0 0.8 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 EEQ27233.1 - 0.059 13.6 1.4 0.17 12.1 1.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prok-RING_4 PF14447.6 EEQ27233.1 - 0.11 12.4 0.1 0.11 12.4 0.1 4.8 6 1 1 7 7 6 0 Prokaryotic RING finger family 4 zf-C2H2_4 PF13894.6 EEQ27233.1 - 0.39 11.7 0.0 0.39 11.7 0.0 5.1 5 1 0 5 5 5 0 C2H2-type zinc finger UBZ_FAAP20 PF15750.5 EEQ27233.1 - 0.41 10.6 5.7 0.49 10.4 0.5 3.4 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger C6_DPF PF10170.9 EEQ27233.1 - 0.74 10.2 5.7 0.29 11.5 0.3 2.6 2 0 0 2 2 2 0 Cysteine-rich domain FYVE_2 PF02318.16 EEQ27233.1 - 4.4 7.5 16.2 6.8 6.9 5.6 3.3 2 1 1 3 3 3 0 FYVE-type zinc finger HypA PF01155.19 EEQ27233.1 - 8.2 6.5 11.2 1.4 9.0 0.1 3.3 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PKD_channel PF08016.12 EEQ27234.1 - 0.049 12.3 15.2 0.12 11.0 10.6 2.8 2 1 0 2 2 2 0 Polycystin cation channel EIF_2_alpha PF07541.12 EEQ27235.1 - 3.9e-36 123.7 0.0 8.1e-36 122.6 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EEQ27235.1 - 1.6e-13 50.8 0.9 3e-13 49.9 0.9 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Sulfate_transp PF00916.20 EEQ27236.1 - 5.6e-74 249.2 13.5 7.8e-74 248.7 13.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EEQ27236.1 - 3e-15 55.9 0.0 4.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EEQ27236.1 - 0.0064 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EEQ27236.1 - 1.8 9.0 11.8 0.97 9.9 5.5 2.9 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily CENP-L PF13092.6 EEQ27237.1 - 2.2e-51 174.3 0.1 2.8e-51 174.0 0.1 1.1 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Cue1_U7BR PF18499.1 EEQ27237.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 DUF3638 PF12340.8 EEQ27238.1 - 3.7e-74 248.9 0.0 9.1e-74 247.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EEQ27238.1 - 1.1e-14 53.5 0.1 2.6e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF1690 PF07956.11 EEQ27238.1 - 0.43 11.0 0.0 0.43 11.0 0.0 3.2 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) Acetyltransf_7 PF13508.7 EEQ27239.1 - 3.4e-06 27.4 0.0 5.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ27239.1 - 3.5e-06 27.2 0.0 4.9e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ27239.1 - 3e-05 24.0 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EEQ27239.1 - 0.091 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Palm_thioest PF02089.15 EEQ27240.1 - 1.4e-85 287.0 0.0 1.6e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EEQ27240.1 - 0.012 15.2 0.0 0.053 13.2 0.0 2.1 3 0 0 3 3 3 0 alpha/beta hydrolase fold Lipase_2 PF01674.18 EEQ27240.1 - 0.013 15.1 0.0 0.078 12.5 0.0 2.1 1 1 0 1 1 1 0 Lipase (class 2) DUF915 PF06028.11 EEQ27240.1 - 0.031 13.6 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) HTH_18 PF12833.7 EEQ27240.1 - 0.18 12.1 0.0 3.1 8.2 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain Pap_E4 PF02711.14 EEQ27241.1 - 3.8 8.5 8.8 17 6.5 0.9 3.2 2 0 0 2 2 2 0 E4 protein DEC-1_N PF04625.13 EEQ27242.1 - 1.7 7.5 8.1 2.2 7.2 8.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Trypan_PARP PF05887.11 EEQ27242.1 - 3.2 7.7 21.2 6.4 6.8 21.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3328 PF11807.8 EEQ27243.1 - 3.1e-45 154.7 0.1 4.4e-45 154.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) IL28A PF15177.6 EEQ27244.1 - 0.059 13.2 0.4 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 Interleukin-28A MCU PF04678.13 EEQ27244.1 - 0.11 12.6 0.3 0.18 11.9 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter zf-C2H2 PF00096.26 EEQ27244.1 - 0.7 10.5 7.2 3.4 8.3 0.3 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.10 EEQ27245.1 - 1.8e-66 224.4 0.0 1e-65 221.9 0.0 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Atg8 PF02991.16 EEQ27246.1 - 4.2e-37 126.5 0.0 4.8e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EEQ27246.1 - 0.0018 18.6 0.0 0.0023 18.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Peptidase_S10 PF00450.22 EEQ27247.1 - 7.1e-89 299.1 0.1 8.7e-89 298.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Methyltransf_16 PF10294.9 EEQ27248.1 - 7.2e-14 51.9 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EEQ27248.1 - 0.00036 20.4 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ27248.1 - 0.011 16.5 0.0 0.031 15.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 EEQ27248.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.17 EEQ27248.1 - 0.023 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF3403 PF11883.8 EEQ27248.1 - 0.13 12.4 0.5 0.26 11.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3403) HMMR_N PF15905.5 EEQ27249.1 - 0.008 15.7 0.7 0.0089 15.5 0.7 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal MFS_1 PF07690.16 EEQ27250.1 - 2.5e-39 135.2 35.7 5.9e-37 127.4 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ27250.1 - 5.2e-08 32.2 12.2 5.2e-08 32.2 12.2 3.1 2 2 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EEQ27250.1 - 0.00044 18.7 4.3 0.021 13.2 0.0 3.0 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EEQ27250.1 - 0.0012 17.3 2.5 0.0012 17.3 2.5 2.3 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 EEQ27250.1 - 0.014 14.2 24.6 0.047 12.5 4.0 3.5 2 2 1 3 3 3 0 MFS_1 like family F-box PF00646.33 EEQ27252.1 - 4.4e-05 23.2 0.1 0.00016 21.5 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EEQ27252.1 - 0.007 16.2 0.2 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 EEQ27252.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 F-box AlaDh_PNT_N PF05222.15 EEQ27253.1 - 3.1e-27 95.5 0.0 4.9e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EEQ27253.1 - 0.00053 19.4 0.0 0.0009 18.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAR PF03114.18 EEQ27254.1 - 3.3e-67 226.6 7.5 4.2e-67 226.3 7.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EEQ27254.1 - 5.3e-13 48.4 0.0 1.1e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ27254.1 - 1.6e-11 43.9 0.0 2.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ27254.1 - 5.8e-08 32.3 0.1 1.7e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 EEQ27254.1 - 0.16 11.5 5.6 4.2 6.8 2.5 2.2 2 0 0 2 2 2 0 Vps5 C terminal like BAR_3 PF16746.5 EEQ27254.1 - 0.41 10.3 9.5 2 8.1 9.5 2.3 1 1 0 1 1 1 0 BAR domain of APPL family TMPIT PF07851.13 EEQ27254.1 - 0.64 9.2 7.7 1.9 7.7 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein BRE1 PF08647.11 EEQ27254.1 - 4.2 7.5 11.7 1.5 8.9 0.4 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Ntox47 PF15540.6 EEQ27255.1 - 0.042 14.1 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 47 Asp PF00026.23 EEQ27256.1 - 9.4e-55 186.2 6.3 5.5e-54 183.7 6.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EEQ27256.1 - 0.00032 20.5 0.0 0.00061 19.6 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EEQ27256.1 - 0.005 17.4 1.8 1.6 9.4 0.3 2.9 2 1 0 2 2 2 2 Aspartyl protease AvrPphF-ORF-2 PF09143.10 EEQ27256.1 - 0.046 13.7 0.1 0.072 13.0 0.1 1.3 1 0 0 1 1 1 0 AvrPphF-ORF-2 APH PF01636.23 EEQ27257.1 - 2.6e-13 50.5 0.1 7.4e-13 49.0 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EEQ27257.1 - 0.0059 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase GST_N PF02798.20 EEQ27258.1 - 2.4e-18 66.2 0.5 6.1e-18 65.0 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ27258.1 - 5.9e-18 65.0 0.0 1.3e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EEQ27258.1 - 3.9e-11 43.1 0.0 6.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEQ27258.1 - 4e-11 43.0 0.0 5.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ27258.1 - 8.2e-06 25.9 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ27258.1 - 0.0096 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ERG4_ERG24 PF01222.17 EEQ27259.1 - 2.7e-73 247.2 14.6 3.1e-46 158.0 7.0 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EEQ27259.1 - 0.01 15.4 1.9 0.014 14.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) NB-ARC PF00931.22 EEQ27260.1 - 5.7e-10 38.8 0.0 9.9e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EEQ27260.1 - 3.4e-05 24.3 0.0 8.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ27260.1 - 0.00058 20.1 0.0 0.0019 18.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EEQ27260.1 - 0.006 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ATP_transf PF09830.9 EEQ27261.1 - 5.1e-15 55.4 0.1 5.1e-15 55.4 0.1 1.6 2 0 0 2 2 2 1 ATP adenylyltransferase LEA_6 PF10714.9 EEQ27262.1 - 0.00034 20.6 1.3 0.00057 19.9 1.3 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein 18 Copper-bind PF00127.20 EEQ27262.1 - 0.0013 19.1 0.1 0.0026 18.2 0.1 1.5 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EEQ27262.1 - 0.053 13.6 0.3 0.48 10.5 0.1 2.0 1 1 1 2 2 2 0 Cupredoxin-like domain GSH-S_N PF02951.14 EEQ27262.1 - 0.22 11.6 0.0 0.56 10.3 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain Aminotran_5 PF00266.19 EEQ27263.1 - 4.3e-94 315.5 0.0 5.2e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EEQ27263.1 - 4.2e-07 29.5 0.0 6.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EEQ27263.1 - 1.1e-05 25.0 0.0 6.1e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EEQ27263.1 - 0.021 13.5 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EEQ27263.1 - 0.078 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.18 EEQ27264.1 - 2.7e-154 514.1 0.0 3.1e-154 513.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.13 EEQ27265.1 - 5.1e-36 123.2 0.0 8.4e-36 122.5 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EEQ27265.1 - 4.7e-21 74.5 0.4 1.8e-20 72.7 0.0 2.1 2 0 0 2 2 2 1 Vps23 core domain ADIP PF11559.8 EEQ27265.1 - 0.0019 18.3 2.3 0.0031 17.6 2.3 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Spidroin_N PF16763.5 EEQ27265.1 - 0.013 15.5 0.9 0.024 14.6 0.9 1.3 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Halo_GVPC PF05465.13 EEQ27265.1 - 0.029 14.6 1.2 0.056 13.7 1.2 1.5 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat UQ_con PF00179.26 EEQ27265.1 - 0.06 13.0 0.7 0.19 11.4 0.1 2.2 3 0 0 3 3 3 0 Ubiquitin-conjugating enzyme TPR_MLP1_2 PF07926.12 EEQ27265.1 - 0.17 12.0 1.6 0.88 9.6 0.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.6 EEQ27265.1 - 0.18 12.3 0.7 0.3 11.5 0.7 1.3 1 0 0 1 1 1 0 Snapin/Pallidin DUF3450 PF11932.8 EEQ27265.1 - 0.18 11.1 1.1 0.29 10.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4686 PF15742.5 EEQ27265.1 - 0.26 10.4 0.7 0.37 9.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) STE2 PF02116.15 EEQ27266.1 - 7.7e-95 317.4 27.4 9.1e-95 317.2 27.4 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PufQ PF05398.11 EEQ27266.1 - 0.14 12.3 4.3 12 6.1 0.1 3.5 3 0 0 3 3 3 0 PufQ cytochrome subunit Kdo PF06293.14 EEQ27267.1 - 2.2e-09 37.0 0.0 0.00094 18.6 0.0 3.1 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ27267.1 - 7.3e-08 32.6 0.0 0.018 15.0 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 EEQ27267.1 - 3.2e-07 30.0 0.0 5.5e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EEQ27267.1 - 0.0027 16.5 0.0 0.0036 16.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EEQ27267.1 - 0.0028 17.3 0.0 0.063 12.9 0.0 2.5 3 0 0 3 3 3 1 RIO1 family Pkinase_Tyr PF07714.17 EEQ27267.1 - 0.0042 16.4 0.0 0.0086 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 EEQ27267.1 - 0.023 14.3 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EEQ27267.1 - 0.042 12.7 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 EEQ27267.1 - 0.071 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Aldo_ket_red PF00248.21 EEQ27268.1 - 2.5e-14 53.2 0.0 3.5e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 EEQ27269.1 - 8.1e-53 178.2 1.9 9.7e-53 177.9 1.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EEQ27269.1 - 0.056 14.2 0.2 0.1 13.3 0.2 1.5 1 1 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 EEQ27270.1 - 1.5e-63 214.1 0.0 2.1e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Filament PF00038.21 EEQ27271.1 - 0.0011 18.6 17.7 0.0011 18.6 17.7 3.9 1 1 2 3 3 3 2 Intermediate filament protein Trypan_PARP PF05887.11 EEQ27271.1 - 0.03 14.3 21.5 0.095 12.7 21.5 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NPV_P10 PF05531.12 EEQ27271.1 - 0.089 13.3 12.6 0.48 10.9 1.2 4.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein TSC22 PF01166.18 EEQ27271.1 - 0.19 12.1 0.1 0.19 12.1 0.1 5.1 5 1 1 6 6 6 0 TSC-22/dip/bun family Fez1 PF06818.15 EEQ27271.1 - 0.67 10.4 64.4 0.3 11.5 10.6 3.8 3 1 1 4 4 4 0 Fez1 LCIB_C_CA PF18599.1 EEQ27271.1 - 3.1 7.1 7.5 0.68 9.2 3.3 2.1 1 1 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases FlaC_arch PF05377.11 EEQ27271.1 - 4.3 7.8 32.0 11 6.5 0.2 6.6 6 2 1 7 7 7 0 Flagella accessory protein C (FlaC) N2227 PF07942.12 EEQ27272.1 - 3e-64 216.8 0.0 4.4e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EEQ27272.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27272.1 - 0.044 14.4 0.0 0.27 11.9 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain NFRKB_winged PF14465.6 EEQ27272.1 - 0.066 13.4 0.2 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 NFRKB Winged Helix-like Binary_toxB_3 PF17476.2 EEQ27273.1 - 0.087 13.0 0.0 5.2 7.3 0.0 2.2 1 1 1 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA domain 3 Abhydrolase_6 PF12697.7 EEQ27274.1 - 1.8e-19 71.3 0.0 2.1e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ27274.1 - 0.00053 19.7 0.1 0.00067 19.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ27274.1 - 0.00076 18.8 0.1 0.0054 16.0 0.0 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EEQ27274.1 - 0.03 13.4 0.0 0.2 10.7 0.0 2.1 1 1 1 2 2 2 0 Chlorophyllase Chlorophyllase2 PF12740.7 EEQ27274.1 - 0.079 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 EEQ27274.1 - 0.091 12.5 0.0 0.31 10.7 0.0 1.8 1 1 1 2 2 2 0 PGAP1-like protein COPIIcoated_ERV PF07970.12 EEQ27275.1 - 4.8e-33 114.9 0.0 1e-32 113.8 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EEQ27275.1 - 2.5e-24 85.4 0.0 4.1e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 EEQ27276.1 - 1.8e-52 178.3 0.0 2.6e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27276.1 - 7.3e-19 68.0 0.1 1.4e-18 67.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pex24p PF06398.11 EEQ27277.1 - 5.8e-84 282.2 0.2 7.2e-84 281.9 0.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 EEQ27277.1 - 0.012 14.1 0.2 0.018 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FMO-like PF00743.19 EEQ27278.1 - 0.15 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Nop16 PF09420.10 EEQ27280.1 - 1.6e-70 237.4 17.7 1.9e-70 237.2 17.7 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 PCB_OB PF17092.5 EEQ27280.1 - 0.12 13.2 5.2 0.11 13.2 2.0 2.2 2 1 0 2 2 2 0 Penicillin-binding protein OB-like domain Zip PF02535.22 EEQ27281.1 - 4e-60 203.8 11.2 1.1e-59 202.3 11.2 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.14 EEQ27282.1 - 4.3e-101 337.8 0.0 5.5e-101 337.4 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EEQ27282.1 - 0.021 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mito_carr PF00153.27 EEQ27283.1 - 6.3e-47 157.5 0.3 2.6e-15 56.1 0.0 3.3 4 0 0 4 4 4 3 Mitochondrial carrier protein DUF3645 PF12359.8 EEQ27283.1 - 0.039 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) ASD1 PF08688.10 EEQ27284.1 - 0.22 11.9 5.1 0.33 11.3 5.1 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 HA1 PF18239.1 EEQ27285.1 - 0.089 12.7 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Hemagglutinin I Ank_2 PF12796.7 EEQ27286.1 - 3.8e-68 226.1 7.1 5.5e-16 58.9 0.1 7.7 1 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ27286.1 - 3.7e-54 180.1 21.6 4.2e-10 39.7 0.0 11.9 4 3 8 12 12 12 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ27286.1 - 4.7e-53 176.9 19.0 1.3e-08 35.2 0.0 13.3 1 1 14 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ27286.1 - 2.2e-45 147.4 14.2 8.5e-05 22.7 0.0 14.4 14 0 0 14 14 14 10 Ankyrin repeat Ank PF00023.30 EEQ27286.1 - 3.3e-40 134.8 26.6 3.1e-06 27.4 0.0 14.6 15 0 0 15 15 15 10 Ankyrin repeat F-box PF00646.33 EEQ27286.1 - 0.015 15.2 0.1 0.015 15.2 0.1 2.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 EEQ27286.1 - 0.03 14.2 1.1 0.082 12.8 1.1 1.7 1 0 0 1 1 1 0 F-box-like Imm_superinfect PF14373.6 EEQ27286.1 - 5 7.1 5.7 89 3.1 0.1 4.4 4 0 0 4 4 4 0 Superinfection immunity protein p450 PF00067.22 EEQ27287.1 - 3.6e-07 29.3 1.3 8.7e-07 28.0 0.6 1.9 2 1 0 2 2 2 1 Cytochrome P450 Chorismate_bind PF00425.18 EEQ27288.1 - 6.1e-85 284.9 0.0 1.6e-84 283.6 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 EEQ27288.1 - 1.4e-34 119.6 0.0 2.1e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EEQ27288.1 - 5.1e-10 39.7 0.0 1.7e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EEQ27288.1 - 1.4e-07 31.5 0.3 4.1e-07 30.0 0.3 1.8 1 1 0 1 1 1 1 Peptidase C26 MFS_1 PF07690.16 EEQ27289.1 - 5.1e-32 111.2 26.8 8.5e-32 110.4 26.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EEQ27289.1 - 0.00056 19.3 1.9 0.00056 19.3 1.9 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CitMHS PF03600.16 EEQ27289.1 - 4.1 6.5 19.4 0.43 9.7 11.7 2.1 2 0 0 2 2 2 0 Citrate transporter Spc7 PF08317.11 EEQ27290.1 - 0.0072 15.2 1.6 0.013 14.4 1.6 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1771 PF08590.10 EEQ27290.1 - 0.091 13.2 6.2 2 8.8 4.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1771) DHDPS PF00701.22 EEQ27291.1 - 2.2e-42 144.7 0.0 2.8e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2014 PF09427.10 EEQ27292.1 - 1e-102 343.0 0.1 1.4e-102 342.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EEQ27292.1 - 7.2e-18 64.3 1.6 1.6e-17 63.2 1.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 EEQ27292.1 - 0.15 12.5 2.2 0.17 12.3 0.8 1.7 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 EEQ27292.1 - 0.71 10.0 3.6 0.63 10.2 2.0 1.7 2 0 0 2 2 2 0 bZIP transcription factor E1-E2_ATPase PF00122.20 EEQ27293.1 - 2.2e-39 134.9 15.3 3.3e-37 127.8 7.7 3.8 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EEQ27293.1 - 1.6e-26 93.2 4.1 1.6e-26 93.2 4.1 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EEQ27293.1 - 2.9e-17 63.7 0.6 5.5e-14 53.0 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEQ27293.1 - 7e-17 60.9 0.1 8.1e-16 57.5 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EEQ27293.1 - 2.8e-12 46.5 0.0 5.6e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEQ27293.1 - 1.4e-05 25.0 1.8 1.4e-05 25.0 1.8 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EEQ27293.1 - 0.013 15.3 0.6 0.04 13.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) RNase_PH_C PF03725.15 EEQ27295.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Pro-kuma_activ PF09286.11 EEQ27296.1 - 5.2e-35 120.8 0.0 8.7e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EEQ27296.1 - 4.6e-08 32.7 0.4 8.9e-08 31.7 0.4 1.5 1 0 0 1 1 1 1 Subtilase family NAD_kinase PF01513.21 EEQ27297.1 - 7.2e-75 251.9 0.0 8.7e-74 248.3 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase DAO PF01266.24 EEQ27298.1 - 6.9e-41 141.0 0.0 8.6e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EEQ27298.1 - 0.0044 16.4 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EEQ27298.1 - 0.0051 16.1 0.1 0.096 11.9 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4988 PF16378.5 EEQ27298.1 - 0.048 13.3 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function Pyr_redox_2 PF07992.14 EEQ27298.1 - 0.049 12.9 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ27298.1 - 0.063 13.3 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EEQ27298.1 - 0.086 13.1 0.1 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EEQ27298.1 - 0.087 12.0 0.0 0.5 9.5 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GAF_2 PF13185.6 EEQ27299.1 - 5.9e-12 46.1 0.0 7e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EEQ27299.1 - 4.2e-07 30.7 0.0 4.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EEQ27299.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 GAF domain SpoVT_C PF15714.5 EEQ27299.1 - 0.15 12.1 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor DEAD PF00270.29 EEQ27300.1 - 1.6e-34 119.2 0.2 6.8e-34 117.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ27300.1 - 7.3e-24 84.3 0.1 2.4e-23 82.6 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EEQ27300.1 - 0.043 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SH3_9 PF14604.6 EEQ27301.1 - 3.6e-26 90.8 1.0 9e-13 47.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EEQ27301.1 - 3.5e-18 64.9 0.2 6.7e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 EEQ27301.1 - 1e-15 57.3 5.2 1.6e-15 56.7 5.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.23 EEQ27301.1 - 6.2e-13 48.8 3.0 8.4e-13 48.4 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 EEQ27301.1 - 4.1e-06 26.4 0.1 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 EEQ27301.1 - 2.3e-05 24.4 0.1 0.15 12.1 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 EEQ27301.1 - 0.00066 19.9 2.1 0.0057 16.9 0.2 3.0 3 0 0 3 3 3 1 Bacterial SH3 domain C1_2 PF03107.16 EEQ27301.1 - 0.042 14.2 5.3 0.08 13.3 5.3 1.4 1 0 0 1 1 1 0 C1 domain FapA PF03961.13 EEQ27301.1 - 1.2 7.7 9.0 0.13 10.8 2.8 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Glyco_hydro_72 PF03198.14 EEQ27302.1 - 4.8e-129 430.1 3.8 5.6e-129 429.9 3.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EEQ27302.1 - 2.1e-06 27.4 0.5 2.1e-05 24.1 0.5 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 EEQ27303.1 - 1.4e-21 77.1 0.0 2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27303.1 - 1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase vATP-synt_AC39 PF01992.16 EEQ27303.1 - 0.15 11.5 0.3 1.9 7.9 0.0 2.3 3 0 0 3 3 3 0 ATP synthase (C/AC39) subunit Arf PF00025.21 EEQ27304.1 - 9.5e-74 246.6 0.1 1.1e-73 246.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EEQ27304.1 - 5.6e-14 52.4 0.0 7.6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EEQ27304.1 - 1.4e-11 44.1 0.0 1.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EEQ27304.1 - 2.1e-10 40.4 0.0 2.5e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EEQ27304.1 - 2.4e-10 40.1 0.3 3.3e-06 26.5 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EEQ27304.1 - 2.7e-08 33.5 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ27304.1 - 2.2e-06 27.7 0.0 4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ27304.1 - 0.00029 20.4 0.0 0.025 14.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EEQ27304.1 - 0.006 16.1 0.5 0.026 14.1 0.5 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 EEQ27304.1 - 0.13 12.8 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Actin PF00022.19 EEQ27305.1 - 2.2e-26 92.5 0.0 6.8e-17 61.2 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 EEQ27305.1 - 2e-05 23.6 0.0 0.011 14.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 EEQ27305.1 - 0.0022 17.2 0.1 0.058 12.6 0.1 2.3 2 0 0 2 2 2 1 Putative actin-like family FtsA PF14450.6 EEQ27305.1 - 0.008 16.6 0.0 0.022 15.2 0.0 1.9 2 1 0 2 2 2 1 Cell division protein FtsA Paf1 PF03985.13 EEQ27306.1 - 8.8e-59 199.6 0.0 1.3e-58 199.0 0.0 1.2 1 0 0 1 1 1 1 Paf1 LON_substr_bdg PF02190.16 EEQ27307.1 - 2.2e-20 73.4 0.0 3.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EEQ27307.1 - 1.3e-10 40.9 8.8 2.7e-10 39.9 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ27307.1 - 1.9e-08 34.5 7.9 4.5e-08 33.3 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EEQ27307.1 - 4.9e-08 32.7 8.2 1.3e-07 31.4 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ27307.1 - 5.4e-08 32.6 7.0 1.1e-07 31.6 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ27307.1 - 2.5e-07 30.6 3.1 2.5e-07 30.6 3.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ27307.1 - 1.4e-06 28.1 7.0 3.3e-06 27.0 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EEQ27307.1 - 8.2e-05 22.7 10.2 0.00018 21.6 10.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EEQ27307.1 - 9.6e-05 22.2 6.7 0.0002 21.2 6.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EEQ27307.1 - 0.00052 20.1 7.6 0.001 19.2 7.6 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EEQ27307.1 - 0.00056 19.7 3.6 0.002 17.9 3.6 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EEQ27307.1 - 0.0013 18.3 7.6 0.0034 17.0 7.6 1.7 1 0 0 1 1 1 1 P-11 zinc finger zf-rbx1 PF12678.7 EEQ27307.1 - 0.0015 18.8 3.8 0.004 17.4 3.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain U-box PF04564.15 EEQ27307.1 - 0.0048 17.0 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EEQ27307.1 - 0.0049 16.7 3.8 0.011 15.5 3.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.11 EEQ27307.1 - 0.31 11.2 4.4 0.7 10.0 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.12 EEQ27307.1 - 0.33 11.0 2.8 0.63 10.1 2.8 1.4 1 0 0 1 1 1 0 zinc-ribbons RICTOR_N PF14664.6 EEQ27308.1 - 8.7e-127 423.2 0.2 1.5e-126 422.4 0.2 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 EEQ27308.1 - 9.6e-38 128.9 0.0 2.9e-36 124.1 0.0 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 EEQ27308.1 - 2.7e-37 126.7 1.6 4e-34 116.5 0.3 4.6 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 EEQ27308.1 - 4.6e-28 97.3 1.6 7.5e-26 90.2 0.1 4.0 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EEQ27308.1 - 1.5e-13 50.7 10.3 1.5e-13 50.7 10.3 2.2 2 0 0 2 2 2 1 Hr1 repeat Uricase PF01014.18 EEQ27309.1 - 1.3e-74 248.6 2.2 6.1e-41 139.7 1.7 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 EEQ27309.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.18 EEQ27310.1 - 1.5e-42 144.8 0.0 1.9e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 EEQ27311.1 - 1.8e-31 109.2 0.2 2e-31 109.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AAR2 PF05282.11 EEQ27312.1 - 3e-92 309.7 0.0 3.5e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.19 EEQ27313.1 - 2.2e-46 156.8 1.1 2.7e-46 156.5 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EEQ27313.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PDH PF02153.17 EEQ27314.1 - 5.9e-15 55.0 0.0 9.3e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EEQ27314.1 - 1.5e-05 25.2 0.0 3.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EEQ27314.1 - 1.6e-05 25.4 0.0 3.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EEQ27314.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EEQ27314.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EEQ27314.1 - 0.034 14.0 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EEQ27314.1 - 0.048 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.9 EEQ27314.1 - 0.098 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Shikimate_DH PF01488.20 EEQ27314.1 - 0.13 12.3 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 EEQ27314.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain CDH-cyt PF16010.5 EEQ27315.1 - 2.3e-25 89.3 0.1 3.4e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EEQ27315.1 - 3.8e-11 43.3 9.5 9.7e-11 41.9 9.5 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 UAA PF08449.11 EEQ27315.1 - 0.015 14.5 0.9 0.029 13.6 0.9 1.4 1 0 0 1 1 1 0 UAA transporter family DOMON PF03351.17 EEQ27315.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 DOMON domain zf-CW PF07496.15 EEQ27315.1 - 0.22 11.6 1.1 0.37 10.9 1.1 1.3 1 0 0 1 1 1 0 CW-type Zinc Finger RRM_occluded PF16842.5 EEQ27316.1 - 0.028 14.3 0.2 0.062 13.2 0.0 1.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif Paf67 PF10255.9 EEQ27317.1 - 1.3e-158 528.3 0.0 1.5e-158 528.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EEQ27317.1 - 0.026 14.6 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 EEQ27317.1 - 0.082 11.9 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Fe-S_biosyn PF01521.20 EEQ27318.1 - 5.8e-10 39.4 0.0 2.3e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis OrsD PF12013.8 EEQ27318.1 - 0.075 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Hemerythrin PF01814.23 EEQ27319.1 - 1.6e-12 48.1 0.7 2.8e-12 47.4 0.7 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Lactamase_B PF00753.27 EEQ27320.1 - 1.6e-08 34.8 0.2 4.2e-06 26.9 0.0 2.4 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EEQ27320.1 - 5.2e-05 22.8 0.0 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aminotran_5 PF00266.19 EEQ27321.1 - 4.6e-07 29.1 0.0 6.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ27321.1 - 0.00023 20.6 0.0 0.00036 20.0 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EEQ27321.1 - 0.037 12.5 0.0 0.047 12.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF1077 PF06417.12 EEQ27322.1 - 3.2e-50 169.1 2.3 4e-50 168.8 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TMEM171 PF15471.6 EEQ27322.1 - 1.7 7.5 8.4 3.2 6.6 8.4 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 Adaptin_N PF01602.20 EEQ27324.1 - 2e-113 379.7 9.1 2.5e-113 379.5 9.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EEQ27324.1 - 1.7e-55 187.5 10.5 1e-54 184.9 1.1 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ27324.1 - 1.5e-12 47.8 5.2 1.3e-07 31.9 0.2 4.5 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 EEQ27324.1 - 9.1e-10 38.0 5.0 0.14 12.5 0.0 5.8 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.9 EEQ27324.1 - 0.00073 19.5 0.1 16 5.6 0.1 4.4 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EEQ27324.1 - 0.00078 19.9 6.0 3.6 8.2 0.1 5.7 6 1 1 7 7 7 2 HEAT-like repeat Arm PF00514.23 EEQ27324.1 - 0.0018 18.2 3.8 3.9 7.7 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EEQ27324.1 - 0.0024 17.5 3.0 1.5 8.3 0.0 3.3 2 1 0 3 3 3 2 CLASP N terminal IFRD PF05004.13 EEQ27324.1 - 0.084 12.0 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Importin_rep_4 PF18808.1 EEQ27324.1 - 0.11 12.8 0.1 12 6.2 0.0 3.5 3 0 0 3 3 3 0 Importin repeat RasGEF_N_2 PF14663.6 EEQ27324.1 - 0.16 12.3 1.1 12 6.4 0.1 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SH3_1 PF00018.28 EEQ27325.1 - 4.6e-10 38.9 0.2 9.5e-10 37.9 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EEQ27325.1 - 9.9e-10 38.0 0.1 2.7e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EEQ27325.1 - 4.1e-08 32.9 0.2 1.1e-07 31.6 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain RPAP2_Rtr1 PF04181.13 EEQ27326.1 - 4.3e-23 81.4 0.1 7.7e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Protamine_P2 PF00841.19 EEQ27326.1 - 0.7 10.4 4.0 6.2 7.4 0.3 2.5 2 0 0 2 2 2 0 Sperm histone P2 Ribosomal_S17e PF00833.18 EEQ27327.1 - 1.7e-59 199.1 0.6 1.9e-59 198.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 EEQ27328.1 - 1.5e-115 386.7 0.0 1.7e-115 386.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit CBM_6 PF03422.15 EEQ27328.1 - 0.16 12.2 0.2 0.46 10.8 0.1 1.7 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) FAT PF02259.23 EEQ27329.1 - 1.9e-132 441.7 0.5 1.9e-132 441.7 0.5 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EEQ27329.1 - 3.3e-69 233.5 0.1 6e-69 232.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EEQ27329.1 - 3.7e-68 228.5 4.6 1.5e-61 207.0 1.2 4.3 3 1 0 3 3 3 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EEQ27329.1 - 2.5e-40 136.9 2.1 2e-39 134.0 0.1 3.7 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EEQ27329.1 - 7.7e-20 71.1 6.3 0.00019 21.7 0.0 9.0 8 1 1 9 9 9 4 HEAT repeats HEAT PF02985.22 EEQ27329.1 - 1.1e-14 53.2 18.9 0.0023 18.0 0.1 12.5 13 0 0 13 13 13 1 HEAT repeat FATC PF02260.20 EEQ27329.1 - 1.4e-14 53.6 0.3 4.4e-14 52.0 0.3 2.0 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 EEQ27329.1 - 3.3e-14 53.0 13.0 0.0023 18.4 0.0 10.9 10 1 2 12 12 11 4 HEAT-like repeat Cnd1 PF12717.7 EEQ27329.1 - 4.2e-09 36.6 0.3 0.77 9.8 0.0 6.6 4 2 3 7 7 7 3 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 EEQ27329.1 - 4.4e-06 26.5 4.9 8.3 6.4 0.0 6.9 6 2 1 7 7 7 3 UME (NUC010) domain CLASP_N PF12348.8 EEQ27329.1 - 0.00072 19.2 0.2 18 4.8 0.0 4.9 5 1 0 5 5 5 0 CLASP N terminal MMS19_C PF12460.8 EEQ27329.1 - 0.0012 18.1 10.4 0.031 13.4 0.1 4.3 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal Tti2 PF10521.9 EEQ27329.1 - 0.0015 18.1 1.2 3.2 7.2 0.0 4.7 3 1 3 6 6 6 1 Tti2 family IFRD PF05004.13 EEQ27329.1 - 0.024 13.7 0.1 0.52 9.4 0.1 2.9 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) TPR_11 PF13414.6 EEQ27329.1 - 0.24 11.1 3.6 2.4 7.9 0.0 3.7 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 EEQ27329.1 - 0.45 11.5 11.3 11 7.2 0.1 5.5 4 1 1 5 5 3 0 Tetratricopeptide repeat Sec7_N PF12783.7 EEQ27329.1 - 0.55 10.1 3.3 8 6.3 0.0 4.4 5 0 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_19 PF14559.6 EEQ27329.1 - 0.58 10.7 3.2 15 6.2 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EEQ27332.1 - 3.7e-08 33.4 0.0 4.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27332.1 - 1e-06 29.3 0.0 2.3e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ27332.1 - 1.4e-06 28.9 0.0 3.5e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ27332.1 - 3.2e-06 27.8 0.0 6.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27332.1 - 3.6e-05 23.6 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EEQ27332.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.12 EEQ27332.1 - 0.04 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 EEQ27332.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MIOX PF05153.15 EEQ27333.1 - 2.6e-124 413.7 2.0 3.2e-124 413.4 2.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 EEQ27333.1 - 0.11 12.8 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 0 HD domain Pam16 PF03656.13 EEQ27334.1 - 2e-36 124.8 0.2 2.4e-36 124.6 0.2 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.11 EEQ27335.1 - 7.7e-96 321.2 0.1 1.1e-95 320.8 0.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DAHP_synth_1 PF00793.20 EEQ27339.1 - 8.2e-101 336.5 0.0 1e-100 336.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2458 PF10454.9 EEQ27340.1 - 2.5e-56 190.0 3.6 4.4e-56 189.2 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) RsdA_SigD_bd PF16751.5 EEQ27340.1 - 0.034 14.4 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region Ribosomal_L50 PF10501.9 EEQ27342.1 - 2.1e-18 66.5 0.0 4.3e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S SAP PF02037.27 EEQ27342.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 SAP domain Rtf2 PF04641.12 EEQ27343.1 - 2e-68 230.6 1.4 2.5e-68 230.3 1.4 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 EEQ27343.1 - 4.6e-08 32.8 0.1 0.01 15.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EEQ27343.1 - 0.00071 19.5 0.1 0.0025 17.8 0.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-NOSIP PF15906.5 EEQ27343.1 - 0.00089 19.3 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 EEQ27343.1 - 0.0078 16.2 0.2 0.015 15.3 0.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EEQ27343.1 - 0.028 14.3 0.1 0.059 13.2 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEQ27343.1 - 0.052 13.4 0.6 0.43 10.5 0.4 2.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EEQ27343.1 - 0.093 13.1 0.2 0.23 11.8 0.2 1.7 1 0 0 1 1 1 0 Ring finger domain PRKCSH-like PF12999.7 EEQ27344.1 - 2.7e-45 154.3 6.3 1.1e-26 93.7 1.7 2.7 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EEQ27344.1 - 1.2e-33 116.0 0.4 3.4e-33 114.5 0.4 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EEQ27344.1 - 7e-09 36.6 0.7 7e-09 36.6 0.7 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF1985 PF09331.11 EEQ27344.1 - 0.063 13.3 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) DUF349 PF03993.12 EEQ27344.1 - 0.078 13.3 3.6 0.31 11.4 3.6 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF2149 PF09919.9 EEQ27344.1 - 0.1 12.9 2.5 0.18 12.1 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) HMG_box PF00505.19 EEQ27344.1 - 0.2 12.1 1.5 0.5 10.8 1.5 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Ax_dynein_light PF10211.9 EEQ27344.1 - 0.47 10.4 9.9 0.59 10.1 8.3 1.9 2 0 0 2 2 2 0 Axonemal dynein light chain NTP_transf_2 PF01909.23 EEQ27345.1 - 7.8e-11 42.1 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EEQ27345.1 - 2.9e-10 40.2 0.0 6.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 EEQ27345.1 - 0.019 15.1 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Aldo_ket_red PF00248.21 EEQ27346.1 - 1e-66 225.1 0.0 1.3e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.13 EEQ27347.1 - 3.3e-25 89.0 24.9 3.1e-24 85.8 22.6 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily COX14 PF14880.6 EEQ27348.1 - 1.4e-17 63.2 0.0 1.4e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Methyltransf_23 PF13489.6 EEQ27349.1 - 2.3e-16 60.1 0.0 7.2e-16 58.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ27349.1 - 3.6e-07 30.8 0.1 0.00022 21.8 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27349.1 - 3.4e-06 27.6 0.0 2e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27349.1 - 0.0027 17.5 0.0 0.33 10.7 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ27349.1 - 0.011 16.5 0.0 0.083 13.6 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ27349.1 - 0.031 13.6 0.0 0.83 8.9 0.0 2.5 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EEQ27349.1 - 0.11 12.2 0.0 0.56 9.9 0.0 1.9 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EEQ27349.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HAD_2 PF13419.6 EEQ27350.1 - 4.3e-25 88.8 0.0 5.6e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ27350.1 - 8.1e-16 58.9 0.0 4e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEQ27350.1 - 2.6e-12 47.5 0.0 3.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ27350.1 - 8.4e-09 35.4 0.4 2e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EEQ27350.1 - 1.1e-06 28.7 0.0 0.00058 19.9 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EEQ27350.1 - 0.021 14.6 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase Hydrolase_3 PF08282.12 EEQ27350.1 - 0.032 14.0 0.3 0.49 10.1 0.0 2.4 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase MTD PF01993.18 EEQ27350.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Peptidase_M35 PF02102.15 EEQ27351.1 - 9.7e-99 330.6 3.8 1.2e-98 330.3 3.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EEQ27351.1 - 6.9e-42 143.4 2.6 1.4e-41 142.5 2.6 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EEQ27351.1 - 9.8e-06 25.3 1.9 2.3e-05 24.1 1.9 1.6 1 1 0 1 1 1 1 Putative peptidase family DUF4758 PF15950.5 EEQ27351.1 - 0.22 11.8 2.5 0.16 12.3 0.7 1.9 2 1 0 2 2 2 0 Putative sperm flagellar membrane protein HC2 PF07382.11 EEQ27352.1 - 0.0064 16.6 14.8 0.012 15.7 14.8 1.4 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Actin PF00022.19 EEQ27353.1 - 2.6e-143 477.5 0.0 3e-143 477.3 0.0 1.0 1 0 0 1 1 1 1 Actin ATG22 PF11700.8 EEQ27354.1 - 1.6e-199 663.5 13.5 1.8e-199 663.3 13.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EEQ27354.1 - 2.9e-05 23.2 51.0 0.043 12.7 27.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ27354.1 - 0.31 9.6 35.4 0.058 12.0 8.7 2.9 3 0 0 3 3 3 0 MFS/sugar transport protein Mpp10 PF04006.12 EEQ27355.1 - 1e-110 371.1 46.8 6.5e-110 368.4 46.8 1.8 1 1 0 1 1 1 1 Mpp10 protein Inositol_P PF00459.25 EEQ27355.1 - 0.14 11.7 0.4 0.51 9.8 0.1 2.0 2 0 0 2 2 2 0 Inositol monophosphatase family HJURP_mid PF12346.8 EEQ27355.1 - 0.39 11.2 4.7 0.27 11.7 1.9 2.1 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat Methyltransf_16 PF10294.9 EEQ27356.1 - 7.5e-46 156.0 0.0 9.7e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 EEQ27356.1 - 0.0034 17.1 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 EEQ27356.1 - 0.0074 15.9 0.1 0.015 14.9 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EEQ27356.1 - 0.034 13.5 0.1 0.047 13.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AhpC-TSA PF00578.21 EEQ27358.1 - 2.2e-22 79.3 0.0 3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EEQ27358.1 - 2.9e-12 46.5 0.0 4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EEQ27358.1 - 0.0072 16.4 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme SWIRM-assoc_2 PF16496.5 EEQ27358.1 - 0.45 9.3 6.9 0.59 8.9 6.9 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pox_Ag35 PF03286.14 EEQ27358.1 - 1.9 8.3 8.2 2.8 7.7 8.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NARP1 PF12569.8 EEQ27358.1 - 2.4 7.0 5.6 3.1 6.6 5.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CH PF00307.31 EEQ27359.1 - 4.9e-75 248.7 0.0 4.7e-20 71.8 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EEQ27359.1 - 3.6e-07 30.5 2.3 3.8e-06 27.3 0.6 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EEQ27359.1 - 0.00017 21.3 0.8 0.024 14.6 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain CAMSAP_CH PF11971.8 EEQ27359.1 - 0.00041 20.1 0.0 0.67 9.8 0.0 3.8 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_1 PF00036.32 EEQ27359.1 - 0.0022 17.4 1.7 1.3 8.8 0.1 3.4 3 0 0 3 3 3 2 EF hand Hydantoinase_B PF02538.14 EEQ27360.1 - 6.6e-222 737.5 0.1 9e-222 737.0 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EEQ27360.1 - 4.6e-102 341.2 0.8 4.6e-102 341.2 0.8 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EEQ27360.1 - 7.9e-60 201.6 0.5 3.1e-58 196.4 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DpnI_C PF17726.1 EEQ27360.1 - 0.077 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Dam-replacing HTH domain PC4 PF02229.16 EEQ27361.1 - 4.3e-23 80.7 0.1 7.1e-23 80.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) MIT PF04212.18 EEQ27362.1 - 2.6e-14 53.0 0.8 6.9e-14 51.7 0.8 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Ubiq_cyt_C_chap PF03981.12 EEQ27363.1 - 3.1e-33 114.8 0.7 4.9e-33 114.2 0.1 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone BTB PF00651.31 EEQ27364.1 - 0.0061 16.8 0.0 0.014 15.6 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Fungal_trans_2 PF11951.8 EEQ27365.1 - 3e-33 115.2 2.4 4.3e-33 114.7 2.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EEQ27366.1 - 1.5e-30 106.3 46.6 1.5e-29 103.0 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.24 EEQ27367.1 - 1e-57 195.2 0.0 1.3e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EEQ27367.1 - 4.6e-23 81.3 0.0 8.4e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TIP41 PF04176.13 EEQ27369.1 - 3.4e-71 238.3 0.0 4e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 EEQ27370.1 - 4.8e-70 235.9 0.0 6.2e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27370.1 - 1.4e-42 145.7 0.0 1.9e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ27370.1 - 2.7e-07 30.2 0.0 3.7e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EEQ27370.1 - 0.00014 21.3 0.2 0.00022 20.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EEQ27370.1 - 0.0017 17.4 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EEQ27370.1 - 0.02 14.5 0.1 0.081 12.5 0.0 1.8 1 1 1 2 2 2 0 RIO1 family FTA2 PF13095.6 EEQ27370.1 - 0.085 12.5 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEQ27370.1 - 0.09 12.7 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EEQ27370.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EEQ27370.1 - 0.16 10.7 0.4 0.21 10.3 0.4 1.3 1 1 0 1 1 1 0 Fungal protein kinase Peptidase_M76 PF09768.9 EEQ27371.1 - 1.2e-70 236.8 2.7 1.4e-70 236.5 2.7 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EEQ27371.1 - 0.00048 20.0 0.5 0.001 18.9 0.3 1.6 1 1 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 EEQ27371.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Effector protein CAF20 PF17052.5 EEQ27371.1 - 0.056 13.6 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Cap associated factor Tox-MPTase2 PF15638.6 EEQ27371.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 PALP PF00291.25 EEQ27372.1 - 2.1e-64 217.7 0.1 2.7e-64 217.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EEQ27372.1 - 4.6e-11 43.0 0.0 3.3e-07 30.6 0.0 3.3 4 0 0 4 4 4 2 CBS domain FIST PF08495.10 EEQ27372.1 - 0.12 12.4 0.0 0.63 10.0 0.0 2.2 2 1 0 2 2 2 0 FIST N domain SRPRB PF09439.10 EEQ27373.1 - 1.3e-28 99.6 0.1 5.5e-27 94.4 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EEQ27373.1 - 3e-06 26.8 0.0 0.00033 20.2 0.0 2.8 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 EEQ27373.1 - 6e-05 23.5 0.3 0.00014 22.3 0.1 1.7 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EEQ27373.1 - 6.3e-05 23.0 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEQ27373.1 - 0.0005 19.5 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EEQ27373.1 - 0.0056 17.0 0.1 0.014 15.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EEQ27373.1 - 0.024 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EEQ27373.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EEQ27373.1 - 0.056 13.3 0.7 2.3 8.1 0.2 2.4 2 1 0 2 2 2 0 RsgA GTPase AAA PF00004.29 EEQ27373.1 - 0.062 13.7 0.4 0.39 11.2 0.4 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 EEQ27373.1 - 0.072 12.9 0.1 8.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 EEQ27373.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EEQ27373.1 - 0.086 13.1 0.0 1.3 9.2 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EEQ27373.1 - 0.12 12.9 0.1 0.39 11.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 EEQ27373.1 - 0.14 11.8 0.2 1.4 8.5 0.2 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 EEQ27373.1 - 0.16 12.5 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KRE9 PF05390.11 EEQ27374.1 - 1.5e-12 48.2 3.1 2e-12 47.7 2.0 1.8 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 EEQ27374.1 - 1.5e-09 38.5 0.0 2.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AA_kinase PF00696.28 EEQ27375.1 - 2.8e-36 125.4 1.2 4.1e-36 124.8 1.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EEQ27375.1 - 4.6e-10 39.3 0.2 3.3e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 PUA domain Pkinase PF00069.25 EEQ27376.1 - 5.6e-42 143.9 0.0 1.6e-40 139.1 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27376.1 - 5.7e-24 84.8 0.0 9.2e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ27376.1 - 0.036 14.0 0.1 0.066 13.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AMP-binding PF00501.28 EEQ27377.1 - 2.8e-218 724.6 0.0 5.5e-79 265.7 0.0 4.2 3 1 1 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 EEQ27377.1 - 1.3e-180 601.0 0.0 9.6e-38 130.0 0.0 6.6 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.25 EEQ27377.1 - 1.4e-51 172.7 15.8 1e-09 38.6 0.0 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ27377.1 - 2.3e-14 54.1 0.0 3.4e-06 27.9 0.0 4.5 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain DUF1524 PF07510.11 EEQ27377.1 - 0.1 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) WES_acyltransf PF03007.16 EEQ27377.1 - 0.24 11.1 1.0 81 2.8 0.0 3.9 4 0 0 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain K_oxygenase PF13434.6 EEQ27378.1 - 2.9e-110 368.6 0.0 3.5e-110 368.3 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EEQ27378.1 - 1.3e-05 24.6 0.0 0.11 11.7 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 EEQ27380.1 - 2.3e-25 89.0 0.0 2.9e-11 43.8 0.0 3.7 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ27380.1 - 6.4e-23 80.5 0.0 8.6e-07 29.1 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EEQ27380.1 - 4.7e-21 74.2 0.1 6e-07 29.6 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EEQ27380.1 - 5.6e-21 74.6 0.8 1.6e-06 28.5 0.0 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ27380.1 - 3.3e-20 70.0 2.4 1e-07 31.7 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat DHHC PF01529.20 EEQ27380.1 - 1.4e-08 35.0 5.5 1.4e-08 35.0 5.5 3.0 2 1 1 3 3 3 1 DHHC palmitoyltransferase YfhO PF09586.10 EEQ27380.1 - 0.0069 14.7 6.4 0.011 14.0 6.4 1.2 1 0 0 1 1 1 1 Bacterial membrane protein YfhO HemY_N PF07219.13 EEQ27380.1 - 0.91 9.7 4.5 3 8.1 0.0 3.1 3 0 0 3 3 3 0 HemY protein N-terminus OB_NTP_bind PF07717.16 EEQ27381.1 - 4e-21 75.2 0.0 1e-20 73.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EEQ27381.1 - 2.3e-19 69.7 0.0 2.3e-19 69.7 0.0 3.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ27381.1 - 2.8e-13 50.2 0.0 6.1e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ27381.1 - 4.3e-06 26.6 0.0 8.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PWI PF01480.17 EEQ27381.1 - 1.2e-05 25.5 0.0 3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 PWI domain AAA_22 PF13401.6 EEQ27381.1 - 1.8e-05 25.0 0.0 0.00014 22.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEQ27381.1 - 0.00014 21.7 0.1 0.00032 20.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ27381.1 - 0.001 19.4 0.1 0.0022 18.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEQ27381.1 - 0.0027 16.8 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 EEQ27381.1 - 0.0087 16.2 0.0 0.12 12.5 0.0 2.6 3 0 0 3 3 3 1 Sigma-54 interaction domain SRP54 PF00448.22 EEQ27381.1 - 0.021 14.5 0.2 0.05 13.2 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EEQ27381.1 - 0.1 13.1 0.0 0.1 13.1 0.0 3.8 1 1 1 2 2 1 0 AAA domain AAA_7 PF12775.7 EEQ27381.1 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EEQ27381.1 - 0.18 12.2 1.4 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EEQ27381.1 - 1.7 9.2 5.4 0.54 10.8 0.2 2.8 2 1 1 3 3 3 0 ABC transporter DUF4232 PF14016.6 EEQ27382.1 - 0.13 12.4 0.1 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) PI3_PI4_kinase PF00454.27 EEQ27383.1 - 0.046 13.5 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase APH PF01636.23 EEQ27383.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Lipase_2 PF01674.18 EEQ27383.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Cyt-b5 PF00173.28 EEQ27385.1 - 9.1e-19 67.4 0.2 1e-18 67.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4291 PF14124.6 EEQ27386.1 - 3.2e-72 242.2 0.1 3.7e-72 242.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Mcp5_PH PF12814.7 EEQ27387.1 - 7.9e-27 93.8 0.1 1.1e-16 61.0 0.0 2.4 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 EEQ27387.1 - 3.6e-05 24.3 14.3 8.5e-05 23.1 14.3 1.5 1 0 0 1 1 1 1 Fez1 DUF3584 PF12128.8 EEQ27387.1 - 0.045 11.3 10.2 0.066 10.7 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 EEQ27387.1 - 0.36 10.9 20.3 0.33 11.0 10.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 EEQ27387.1 - 0.36 10.6 4.5 0.72 9.7 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Lebercilin PF15619.6 EEQ27387.1 - 1.9 8.1 15.2 3.2 7.4 15.2 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CCDC-167 PF15188.6 EEQ27387.1 - 5.2 7.5 13.7 1 9.8 3.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 GHMP_kinases_N PF00288.26 EEQ27389.1 - 7.1e-15 55.0 0.0 2e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEQ27389.1 - 2e-10 40.9 0.2 4.7e-10 39.7 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EEQ27389.1 - 0.01 15.4 0.1 0.023 14.3 0.1 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature LigT_PEase PF02834.16 EEQ27389.1 - 0.023 14.9 0.0 0.09 13.0 0.0 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase AMP-binding PF00501.28 EEQ27390.1 - 1.9e-73 247.5 0.0 2.4e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ27390.1 - 2.6e-14 53.9 0.0 6.3e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EEQ27390.1 - 3.4e-14 52.5 0.0 9.4e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Ras PF00071.22 EEQ27391.1 - 3.3e-50 169.8 0.5 7.1e-49 165.5 0.5 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EEQ27391.1 - 4.1e-18 65.7 0.1 8.8e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ27391.1 - 0.00022 20.8 0.0 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family SUIM_assoc PF16619.5 EEQ27391.1 - 0.0075 16.3 1.6 0.017 15.2 1.6 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 AAA_16 PF13191.6 EEQ27391.1 - 0.086 13.2 0.3 0.21 12.0 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EEQ27391.1 - 0.12 11.6 0.6 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 EEQ27391.1 - 0.14 12.1 0.0 9.5 6.1 0.0 2.6 2 1 1 3 3 3 0 RsgA GTPase AAA_25 PF13481.6 EEQ27391.1 - 0.14 11.7 0.1 0.34 10.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EEQ27391.1 - 0.15 11.6 0.2 2.6 7.5 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B MFS_1 PF07690.16 EEQ27392.1 - 3.9e-31 108.3 35.0 5.8e-31 107.7 35.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SHMT PF00464.19 EEQ27394.1 - 3.6e-196 651.5 0.0 4.2e-196 651.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Mor PF08765.11 EEQ27394.1 - 0.12 12.4 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Mor transcription activator family MOSC PF03473.17 EEQ27395.1 - 2.7e-34 118.0 0.0 4.2e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EEQ27395.1 - 1.3e-11 44.4 0.0 5.5e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain WRNPLPNID PF15017.6 EEQ27395.1 - 0.01 16.7 0.7 0.025 15.4 0.7 1.6 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF5534 PF17686.1 EEQ27395.1 - 0.12 12.6 1.6 0.19 12.0 1.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5534) DUF2235 PF09994.9 EEQ27396.1 - 2.5e-92 309.3 0.0 3.1e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Patatin PF01734.22 EEQ27397.1 - 3.6e-15 56.7 0.0 1.1e-14 55.1 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Mg_trans_NIPA PF05653.14 EEQ27398.1 - 1.5e-86 290.2 27.5 2.1e-86 289.7 27.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EEQ27398.1 - 2.2e-05 24.6 5.6 2.2e-05 24.6 5.6 3.2 3 0 0 3 3 3 1 EamA-like transporter family DUF5362 PF17319.2 EEQ27398.1 - 0.2 11.5 6.2 0.23 11.3 0.3 3.3 2 1 0 3 3 3 0 Family of unknown function (DUF5362) BRCT_2 PF16589.5 EEQ27399.1 - 1.5e-06 28.5 0.0 3.6e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EEQ27399.1 - 0.0001 22.2 0.5 0.00032 20.6 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EEQ27399.1 - 0.076 13.4 0.0 0.31 11.5 0.0 2.0 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain HA2 PF04408.23 EEQ27401.1 - 4.6e-17 62.3 0.0 1.5e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ27401.1 - 2.7e-13 50.2 0.1 7.6e-13 48.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ27401.1 - 8.4e-11 41.9 0.0 1.8e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEQ27401.1 - 8.5e-08 32.6 0.1 6.8e-07 29.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 EEQ27401.1 - 1.4e-05 25.3 0.0 3.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 EEQ27401.1 - 0.0087 16.4 0.0 0.051 13.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EEQ27401.1 - 0.018 14.8 0.0 0.065 13.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EEQ27401.1 - 0.028 13.5 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EEQ27401.1 - 0.037 14.5 0.0 0.037 14.5 0.0 3.0 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EEQ27401.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EEQ27401.1 - 0.059 13.9 0.3 0.25 11.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 EEQ27401.1 - 0.071 12.4 0.2 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 KaiC Gcn1_N PF12074.8 EEQ27402.1 - 1e-120 403.4 0.1 9e-120 400.2 0.1 2.9 1 0 0 1 1 1 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EEQ27402.1 - 1.6e-28 96.3 34.4 0.069 13.4 0.1 22.0 25 0 0 25 25 24 7 HEAT repeat HEAT_2 PF13646.6 EEQ27402.1 - 3.1e-20 72.3 33.8 7e-06 26.3 0.0 13.8 11 3 6 17 17 16 7 HEAT repeats HEAT_EZ PF13513.6 EEQ27402.1 - 7.5e-19 67.8 36.2 3.8e-07 30.5 0.0 16.9 20 1 1 21 21 20 3 HEAT-like repeat Cnd1 PF12717.7 EEQ27402.1 - 1e-12 48.4 9.3 0.0063 16.6 0.1 8.5 7 1 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EEQ27402.1 - 1.1e-11 45.2 0.0 0.62 10.7 0.0 8.1 6 1 2 8 8 8 2 Vacuolar 14 Fab1-binding region ParcG PF10274.9 EEQ27402.1 - 3e-06 27.5 5.9 0.27 11.3 0.0 6.5 6 1 1 7 7 7 2 Parkin co-regulated protein CLASP_N PF12348.8 EEQ27402.1 - 4.1e-05 23.3 0.0 1.8 8.1 0.0 6.1 4 1 2 6 6 6 1 CLASP N terminal TIP120 PF08623.10 EEQ27402.1 - 9.5e-05 22.2 5.1 0.0098 15.7 0.0 5.6 7 0 0 7 7 7 1 TATA-binding protein interacting (TIP20) DUF937 PF06078.11 EEQ27402.1 - 0.00019 22.0 1.1 4.7 7.8 0.0 5.4 4 1 0 4 4 4 1 Bacterial protein of unknown function (DUF937) Tti2 PF10521.9 EEQ27402.1 - 0.019 14.6 5.0 19 4.7 0.0 6.0 5 1 1 6 6 6 0 Tti2 family Cohesin_HEAT PF12765.7 EEQ27402.1 - 0.025 14.9 3.9 31 5.0 0.1 6.1 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 EEQ27402.1 - 0.32 11.2 7.7 25 5.1 0.0 6.5 6 0 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 EEQ27402.1 - 1 8.4 20.5 0.13 11.3 0.1 5.7 6 0 0 6 6 6 0 Interferon-related developmental regulator (IFRD) Ribosomal_L19e PF01280.20 EEQ27403.1 - 1.4e-61 206.8 6.2 1.4e-61 206.8 6.2 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DUF4239 PF14023.6 EEQ27403.1 - 0.11 12.3 1.3 0.18 11.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) TRAP-gamma PF07074.12 EEQ27403.1 - 0.19 11.2 3.6 0.27 10.8 3.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Zn_clus PF00172.18 EEQ27409.1 - 1.6e-09 37.8 11.0 2.5e-09 37.1 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EEQ27411.1 - 1.9e-34 118.9 0.1 2.8e-34 118.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ27411.1 - 4.3e-26 91.9 0.0 6.3e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ27411.1 - 4.2e-08 33.3 3.7 1.8e-05 24.7 4.9 2.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EEQ27411.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EEQ27411.1 - 0.0026 16.9 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF3216 PF11505.8 EEQ27411.1 - 0.015 15.5 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Fib_alpha PF08702.10 EEQ27412.1 - 7.2 6.8 14.8 2 8.6 4.4 3.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CorA PF01544.18 EEQ27413.1 - 2.4e-40 138.7 0.3 5e-40 137.7 0.3 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.7 EEQ27414.1 - 4.8e-140 467.3 0.1 4.8e-140 467.3 0.1 2.8 3 1 1 4 4 4 1 Vacuolar segregation subunit 7 EIIBC-GUT_N PF03612.14 EEQ27414.1 - 0.17 11.6 1.7 0.32 10.7 1.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Spt20 PF12090.8 EEQ27414.1 - 1.2 8.7 15.2 2.4 7.7 15.2 1.4 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 EEQ27414.1 - 1.7 7.7 9.1 4 6.4 9.1 1.6 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 EEQ27414.1 - 1.8 7.3 4.5 3.3 6.4 4.5 1.5 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 EEQ27414.1 - 2.6 7.9 21.3 3.2 7.6 20.5 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Beta-lactamase PF00144.24 EEQ27415.1 - 6.4e-31 107.8 0.0 1.1e-30 107.0 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase NDUF_B12 PF08122.12 EEQ27417.1 - 0.044 13.8 0.7 0.69 10.0 0.1 2.9 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family STALD PF18185.1 EEQ27417.1 - 0.91 8.8 2.7 14 4.9 0.1 2.2 1 1 1 2 2 2 0 Sir2- and TIR-associating SLOG family DUF4473 PF14747.6 EEQ27417.1 - 5.1 7.7 7.9 29 5.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Amidohydro_1 PF01979.20 EEQ27418.1 - 3.9e-16 59.3 0.7 6.5e-16 58.6 0.7 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EEQ27418.1 - 5.2e-11 42.7 3.8 2.9e-09 36.9 0.3 2.1 1 1 0 2 2 2 2 Amidohydrolase family Hydrolase_4 PF12146.8 EEQ27420.1 - 1.5e-20 73.5 0.0 2.4e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ27420.1 - 1.6e-20 73.8 0.2 3.4e-14 53.1 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ27420.1 - 1.3e-16 61.9 0.0 1.6e-16 61.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EEQ27420.1 - 0.00014 20.7 0.0 0.00015 20.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.13 EEQ27420.1 - 0.11 12.2 0.1 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 PGAP1-like protein Fungal_trans PF04082.18 EEQ27421.1 - 2.3e-14 53.0 0.1 2.3e-14 53.0 0.1 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Striatin PF08232.12 EEQ27421.1 - 0.034 14.8 1.6 0.061 13.9 1.6 1.4 1 0 0 1 1 1 0 Striatin family Spore_YpjB PF09577.10 EEQ27421.1 - 0.073 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Ribosomal_L44 PF00935.19 EEQ27422.1 - 2.8e-36 123.8 11.8 4.5e-36 123.2 11.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 ubiquitin PF00240.23 EEQ27423.1 - 6.8e-24 83.4 0.0 7.6e-24 83.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EEQ27423.1 - 4.1e-13 48.9 0.0 4.5e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEQ27423.1 - 9.9e-05 22.7 0.0 0.00029 21.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EEQ27423.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ferritin_2 PF13668.6 EEQ27424.1 - 1.3e-17 64.3 0.1 1.9e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain PilN PF05137.13 EEQ27424.1 - 0.0095 16.1 0.1 4.6 7.4 0.0 2.4 2 0 0 2 2 2 2 Fimbrial assembly protein (PilN) Rav1p_C PF12234.8 EEQ27425.1 - 1e-282 939.4 1.1 1.6e-282 938.7 1.1 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 EEQ27425.1 - 1.7 9.6 14.9 18 6.4 0.1 5.7 5 1 1 6 6 6 0 WD domain, G-beta repeat OPT PF03169.15 EEQ27426.1 - 4.4e-160 534.3 15.7 5e-160 534.1 15.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TraQ PF09679.10 EEQ27426.1 - 0.12 12.3 0.3 0.42 10.6 0.3 2.0 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF4212 PF13937.6 EEQ27426.1 - 1.2 9.6 9.3 9.7 6.6 0.5 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) SH3_9 PF14604.6 EEQ27427.1 - 1.6e-09 37.5 0.0 2.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEQ27427.1 - 5.4e-07 29.1 0.0 8.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EEQ27427.1 - 2.4e-06 27.1 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Apt1 PF10351.9 EEQ27427.1 - 0.75 8.6 4.0 1.1 8.1 4.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4366 PF14283.6 EEQ27427.1 - 2.7 8.0 4.5 10 6.2 2.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) SPESP1 PF15754.5 EEQ27427.1 - 5.5 6.1 10.0 9.6 5.3 10.0 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Podoplanin PF05808.11 EEQ27427.1 - 8.6 6.4 14.3 0.35 11.0 6.4 2.4 2 1 1 3 3 3 0 Podoplanin ABC_tran PF00005.27 EEQ27428.1 - 2.6e-40 138.1 0.0 2.9e-19 70.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ27428.1 - 6.3e-30 104.7 33.3 5.1e-23 82.1 17.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EEQ27428.1 - 5.8e-11 42.3 0.0 0.00092 18.7 0.0 3.3 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEQ27428.1 - 6.6e-05 22.9 3.7 0.11 12.3 0.0 4.0 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EEQ27428.1 - 0.00026 21.4 0.1 0.0064 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EEQ27428.1 - 0.0008 19.7 0.2 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EEQ27428.1 - 0.00084 19.8 1.8 0.036 14.5 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EEQ27428.1 - 0.013 14.6 0.0 0.053 12.6 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 EEQ27428.1 - 0.013 15.6 0.1 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EEQ27428.1 - 0.021 14.4 0.6 0.051 13.2 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EEQ27428.1 - 0.038 13.7 0.3 1 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EEQ27428.1 - 0.039 13.2 0.0 4 6.7 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_29 PF13555.6 EEQ27428.1 - 0.039 13.7 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 EEQ27428.1 - 0.064 13.5 1.3 15 5.9 0.0 3.7 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Viral_helicase1 PF01443.18 EEQ27428.1 - 0.067 12.9 0.1 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 EEQ27428.1 - 0.068 13.7 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EEQ27428.1 - 0.075 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 EEQ27428.1 - 0.078 12.7 0.0 10 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 EEQ27428.1 - 0.11 12.4 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EEQ27428.1 - 0.14 11.7 0.1 0.38 10.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ27428.1 - 0.21 11.5 1.0 1.2 9.0 1.0 2.4 1 1 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EEQ27428.1 - 0.22 11.6 0.2 10 6.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pkinase PF00069.25 EEQ27429.1 - 2.6e-40 138.4 0.0 3.6e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27429.1 - 1.6e-14 53.8 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ27429.1 - 0.0043 15.9 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EEQ27429.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KIX_2 PF16987.5 EEQ27429.1 - 0.027 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 KIX domain Kinase-like PF14531.6 EEQ27429.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EEQ27429.1 - 0.042 13.8 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EEQ27429.1 - 0.055 13.1 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 muHD PF10291.9 EEQ27430.1 - 1.7e-73 247.4 0.0 2.5e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EEQ27430.1 - 0.00018 21.7 0.0 0.00061 20.0 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Ndc1_Nup PF09531.10 EEQ27430.1 - 0.033 12.9 0.3 0.033 12.9 0.3 2.6 2 1 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Laminin_II PF06009.12 EEQ27430.1 - 0.1 12.6 4.6 0.2 11.7 3.8 1.9 2 0 0 2 2 2 0 Laminin Domain II Peptidase_M20 PF01546.28 EEQ27431.1 - 5.5e-29 101.3 0.0 9e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEQ27431.1 - 9.4e-16 57.7 0.0 3.3e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EEQ27431.1 - 0.0016 18.1 0.0 0.0064 16.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 MAD PF05557.13 EEQ27432.1 - 2.2e-56 191.6 82.3 1.3e-47 162.6 83.5 2.7 2 1 0 2 2 2 2 Mitotic checkpoint protein Spc7 PF08317.11 EEQ27432.1 - 0.0014 17.6 22.0 0.0014 17.6 22.0 5.6 2 1 5 7 7 7 2 Spc7 kinetochore protein DUF1664 PF07889.12 EEQ27432.1 - 0.0079 16.2 4.6 0.0079 16.2 4.6 6.4 4 2 1 6 6 6 2 Protein of unknown function (DUF1664) Arginosuc_synth PF00764.19 EEQ27433.1 - 1.3e-128 429.6 0.0 2.6e-128 428.6 0.0 1.4 1 1 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EEQ27433.1 - 0.0025 17.3 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EEQ27433.1 - 0.021 13.6 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Glyco_hydro_114 PF03537.13 EEQ27433.1 - 0.15 11.3 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 DUF2624 PF11116.8 EEQ27433.1 - 0.16 12.9 0.0 0.39 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) DNA_pol3_gamma3 PF12169.8 EEQ27433.1 - 0.16 11.9 0.1 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III RasGEF PF00617.19 EEQ27434.1 - 4.2e-43 147.6 0.0 6.7e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EEQ27434.1 - 3.1e-13 49.9 0.0 6.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif DIL PF01843.19 EEQ27435.1 - 3.4e-29 101.2 1.6 3.4e-29 101.2 1.6 2.0 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 EEQ27435.1 - 1.4e-12 48.1 0.2 6.6e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EEQ27435.1 - 5.8e-09 36.0 0.3 0.0064 16.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EEQ27435.1 - 8e-09 35.6 0.0 4.6e-05 23.6 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ27435.1 - 1.5e-07 31.8 0.4 0.0003 21.3 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ27435.1 - 2.6e-05 24.2 1.3 0.012 16.1 0.0 4.1 4 1 0 4 4 4 1 Ankyrin repeat BTB PF00651.31 EEQ27437.1 - 4.2e-13 49.5 0.3 9.6e-13 48.3 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Bacteriocin_IIi PF11758.8 EEQ27437.1 - 0.073 12.9 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin SKG6 PF08693.10 EEQ27438.1 - 0.00011 21.6 0.1 0.0002 20.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RabGAP-TBC PF00566.18 EEQ27439.1 - 3.8e-36 124.8 0.0 5.7e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DPCD PF14913.6 EEQ27439.1 - 0.017 14.5 0.4 0.038 13.4 0.4 1.5 1 0 0 1 1 1 0 DPCD protein family Limkain-b1 PF11608.8 EEQ27439.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 DUF4650 PF15509.6 EEQ27439.1 - 0.44 9.8 6.2 0.87 8.8 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) TPP_enzyme_N PF02776.18 EEQ27440.1 - 5.8e-40 136.7 0.0 1.5e-39 135.4 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EEQ27440.1 - 1.7e-19 70.1 0.1 2.4e-18 66.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEQ27440.1 - 1e-14 54.4 0.0 2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Mo25 PF08569.11 EEQ27441.1 - 2.2e-129 431.5 0.0 2.5e-129 431.4 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Methyltransf_25 PF13649.6 EEQ27442.1 - 1.9e-10 41.3 0.0 5.8e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27442.1 - 2.4e-09 37.2 0.0 4.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27442.1 - 1.2e-08 35.5 0.0 2.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEQ27442.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EEQ27442.1 - 8.3e-06 25.7 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEQ27442.1 - 5.3e-05 22.8 0.1 9.3e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EEQ27442.1 - 6.3e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EEQ27442.1 - 0.00054 19.0 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RasGAP_C PF03836.15 EEQ27442.1 - 0.0022 18.2 0.2 0.0045 17.1 0.2 1.4 1 0 0 1 1 1 1 RasGAP C-terminus TehB PF03848.14 EEQ27442.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 EEQ27442.1 - 0.013 16.2 0.0 0.03 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ27442.1 - 0.059 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EEQ27442.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EEQ27442.1 - 0.075 12.3 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 EEQ27442.1 - 0.075 14.1 0.0 0.22 12.5 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EEQ27442.1 - 0.14 12.2 0.1 0.33 10.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Cir_N PF10197.9 EEQ27443.1 - 3e-06 27.3 9.4 3e-06 27.3 9.4 4.0 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Bestrophin PF01062.21 EEQ27443.1 - 0.5 9.7 1.0 0.94 8.8 1.0 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel AAA PF00004.29 EEQ27444.1 - 1.1e-53 181.2 0.0 1.6e-38 132.1 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ27444.1 - 1.6e-10 40.6 0.0 3.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EEQ27444.1 - 7e-10 39.5 0.1 0.001 19.5 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain CDC48_2 PF02933.17 EEQ27444.1 - 1.2e-09 37.8 0.2 2.6e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 EEQ27444.1 - 3.7e-09 37.0 0.0 0.00046 20.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EEQ27444.1 - 2.9e-08 33.8 0.0 0.0019 18.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEQ27444.1 - 4.8e-08 32.9 0.1 0.0067 16.2 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_N PF02359.18 EEQ27444.1 - 7.1e-08 32.5 0.0 1.9e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_18 PF13238.6 EEQ27444.1 - 8.7e-08 32.8 0.0 0.019 15.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.13 EEQ27444.1 - 9.6e-08 31.6 0.0 0.0082 15.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 EEQ27444.1 - 2.6e-07 30.2 0.1 0.0052 16.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EEQ27444.1 - 3.5e-07 30.5 0.0 7.8e-05 22.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EEQ27444.1 - 1.1e-06 29.0 0.0 0.071 13.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 EEQ27444.1 - 1.7e-06 28.3 0.0 0.04 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EEQ27444.1 - 3.1e-06 27.3 0.0 0.1 12.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 EEQ27444.1 - 5.5e-06 26.2 0.0 0.015 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EEQ27444.1 - 1.9e-05 24.5 0.0 0.092 12.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 EEQ27444.1 - 2.2e-05 24.4 0.2 0.033 14.1 0.0 3.1 2 1 0 2 2 2 1 NACHT domain TsaE PF02367.17 EEQ27444.1 - 4.3e-05 23.5 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EEQ27444.1 - 5.2e-05 22.6 0.3 0.11 11.7 0.0 2.6 3 0 0 3 3 2 2 NB-ARC domain ATPase PF06745.13 EEQ27444.1 - 8e-05 22.1 0.9 0.022 14.1 0.2 2.8 2 1 1 3 3 3 1 KaiC AAA_7 PF12775.7 EEQ27444.1 - 9.6e-05 22.0 0.9 0.026 14.0 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EEQ27444.1 - 0.00019 21.7 0.0 0.58 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 EEQ27444.1 - 0.00037 20.9 0.1 0.19 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EEQ27444.1 - 0.00039 21.0 0.3 0.056 14.0 0.1 2.7 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 EEQ27444.1 - 0.00042 20.2 0.0 0.63 9.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EEQ27444.1 - 0.00044 19.9 0.2 1.2 8.7 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EEQ27444.1 - 0.00047 20.0 0.0 0.6 10.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EEQ27444.1 - 0.00067 19.2 0.3 1.4 8.4 0.0 2.7 3 0 0 3 3 3 2 PhoH-like protein Sigma54_activat PF00158.26 EEQ27444.1 - 0.00072 19.3 0.0 0.65 9.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 EEQ27444.1 - 0.0012 18.6 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEQ27444.1 - 0.0013 19.1 0.1 0.58 10.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 EEQ27444.1 - 0.0035 16.6 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 EEQ27444.1 - 0.0047 16.0 0.0 0.48 9.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 EEQ27444.1 - 0.0047 16.9 0.2 17 5.3 0.0 3.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EEQ27444.1 - 0.0064 16.4 0.1 8.4 6.3 0.0 3.3 3 0 0 3 3 3 0 NTPase ResIII PF04851.15 EEQ27444.1 - 0.017 15.1 0.0 5.5 7.0 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TniB PF05621.11 EEQ27444.1 - 0.022 14.2 0.2 4.4 6.7 0.1 3.4 3 1 0 3 3 3 0 Bacterial TniB protein Zeta_toxin PF06414.12 EEQ27444.1 - 0.024 13.9 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 EEQ27444.1 - 0.032 13.7 0.1 2 7.8 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SRP54 PF00448.22 EEQ27444.1 - 0.087 12.4 0.2 6.1 6.4 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain IPT PF01745.16 EEQ27444.1 - 0.12 11.8 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Vps4_C PF09336.10 EEQ27444.1 - 0.13 12.3 0.0 0.59 10.2 0.0 2.1 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_29 PF13555.6 EEQ27444.1 - 0.14 11.9 0.1 12 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain KxDL PF10241.9 EEQ27446.1 - 0.19 12.0 0.2 0.98 9.7 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein HATPase_c PF02518.26 EEQ27447.1 - 2.6e-22 79.4 1.0 8.7e-22 77.7 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EEQ27447.1 - 1.4e-21 76.8 0.1 2.7e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EEQ27447.1 - 7.8e-16 57.9 0.0 2.5e-15 56.3 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EEQ27447.1 - 9.2e-08 32.3 2.1 0.47 10.8 0.4 3.8 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 EEQ27447.1 - 0.0053 17.0 0.3 0.024 14.9 0.1 2.2 2 0 0 2 2 2 1 PAS fold HATPase_c PF02518.26 EEQ27448.1 - 2.3e-31 108.6 0.1 8.2e-31 106.8 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EEQ27448.1 - 1e-19 70.7 0.1 2.5e-19 69.5 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EEQ27448.1 - 3.6e-19 68.5 0.0 1.4e-18 66.7 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 EEQ27448.1 - 7.2e-10 39.5 0.1 3.9e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.6 EEQ27448.1 - 7.4e-10 39.3 0.0 2.1e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EEQ27448.1 - 4.5e-07 30.6 0.0 1.8e-06 28.6 0.0 2.1 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 EEQ27448.1 - 5.8e-06 25.9 0.0 9.5e-05 21.9 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.6 EEQ27448.1 - 4.1e-05 23.9 0.0 0.00011 22.6 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 EEQ27448.1 - 0.00014 21.7 0.0 0.00036 20.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_2 PF07719.17 EEQ27448.1 - 0.0011 18.9 2.5 0.75 10.1 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 EEQ27448.1 - 0.0066 16.7 0.1 0.92 9.8 0.0 3.2 2 1 0 3 3 3 1 AAA domain MeaB PF03308.16 EEQ27448.1 - 0.0084 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TPR_1 PF00515.28 EEQ27448.1 - 0.011 15.5 0.8 4.2 7.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3369 PF11849.8 EEQ27448.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) RsgA_GTPase PF03193.16 EEQ27448.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Allantoicase PF03561.15 EEQ27449.1 - 1.4e-89 297.5 0.0 8.5e-44 149.0 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.16 EEQ27450.1 - 1.6e-16 60.7 2.3 1.6e-16 60.7 2.3 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EEQ27450.1 - 0.0049 17.0 9.1 0.047 13.8 3.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 EEQ27450.1 - 0.0065 16.1 8.9 0.16 11.6 4.8 2.5 1 1 1 2 2 2 2 Prokaryotic cytochrome b561 Bax1-I PF01027.20 EEQ27450.1 - 0.053 13.3 14.0 0.46 10.3 14.2 2.0 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2427 PF10348.9 EEQ27450.1 - 0.073 12.9 0.5 0.073 12.9 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) DUF4271 PF14093.6 EEQ27450.1 - 0.096 12.6 4.2 0.089 12.7 3.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF2306 PF10067.9 EEQ27450.1 - 0.29 11.3 8.1 0.58 10.4 0.9 2.5 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) DUF2818 PF10993.8 EEQ27450.1 - 0.3 11.7 3.4 0.95 10.1 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2818) DUF1129 PF06570.11 EEQ27450.1 - 6.4 6.2 8.9 2.7 7.5 2.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1129) tRNA-synt_2b PF00587.25 EEQ27451.1 - 1.7e-19 70.5 0.0 3.8e-19 69.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EEQ27451.1 - 2.6e-05 24.4 7.0 0.012 15.9 0.4 2.2 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DUF812 PF05667.11 EEQ27451.1 - 0.017 14.1 6.9 0.031 13.2 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 EEQ27451.1 - 0.038 13.3 4.8 0.074 12.4 4.8 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding tRNA-synt_2d PF01409.20 EEQ27451.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Flagellar_rod PF05149.12 EEQ27451.1 - 0.09 12.2 4.8 0.049 13.1 2.4 1.6 1 1 1 2 2 2 0 Paraflagellar rod protein Nebulin PF00880.18 EEQ27451.1 - 0.12 12.3 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Nebulin repeat ThiD2 PF17792.1 EEQ27451.1 - 0.43 11.0 2.8 0.91 10.0 2.8 1.5 1 0 0 1 1 1 0 ThiD2 family Exonuc_VII_L PF02601.15 EEQ27451.1 - 1.1 8.7 5.4 1.7 8.1 5.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EEQ27451.1 - 2.3 7.5 8.7 4 6.7 7.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HSCB_C PF07743.13 EEQ27451.1 - 4.7 7.8 8.2 2.7 8.5 1.3 2.4 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain TFIIF_alpha PF05793.12 EEQ27452.1 - 0.014 14.1 4.1 0.051 12.2 4.4 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BTB PF00651.31 EEQ27452.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain FSA_C PF10479.9 EEQ27452.1 - 0.18 9.9 3.1 0.25 9.4 3.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Macoilin PF09726.9 EEQ27452.1 - 2 6.8 3.4 3 6.3 3.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4360 PF14273.6 EEQ27453.1 - 6.8e-51 172.6 0.5 7.7e-51 172.5 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pkinase PF00069.25 EEQ27454.1 - 2.3e-65 220.6 0.0 3.1e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27454.1 - 1.2e-30 106.6 0.0 1e-29 103.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ27454.1 - 0.00011 21.6 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ27454.1 - 0.0032 16.8 0.5 0.046 13.0 0.0 2.6 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EEQ27454.1 - 0.0078 16.2 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EEQ27454.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EEQ27454.1 - 0.077 12.6 0.2 3.3 7.3 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Amino_oxidase PF01593.24 EEQ27457.1 - 3.7e-08 33.1 0.0 6.5e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EEQ27457.1 - 1.1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ27457.1 - 0.0024 17.2 0.1 0.021 14.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ27457.1 - 0.0089 15.3 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEQ27457.1 - 0.013 14.7 0.4 0.033 13.4 0.1 1.7 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 EEQ27457.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EEQ27457.1 - 0.046 13.0 0.1 0.072 12.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 EEQ27457.1 - 0.072 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 EEQ27457.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EEQ27457.1 - 0.14 11.2 0.5 0.27 10.3 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein HNH_2 PF13391.6 EEQ27458.1 - 0.00015 21.8 0.2 0.00038 20.5 0.2 1.7 1 0 0 1 1 1 1 HNH endonuclease DUF1801 PF08818.11 EEQ27458.1 - 0.14 12.7 0.1 0.65 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DU1801) HTH_41 PF14502.6 EEQ27460.1 - 0.021 14.5 0.2 8.4 6.2 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1664 PF07889.12 EEQ27460.1 - 0.033 14.2 1.0 3.3 7.8 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Imm7 PF15585.6 EEQ27460.1 - 0.04 14.2 0.1 0.26 11.6 0.0 2.1 1 1 1 2 2 2 0 Immunity protein 7 Rx_N PF18052.1 EEQ27460.1 - 0.079 13.2 0.7 1.8 8.9 0.7 2.5 1 1 0 1 1 1 0 Rx N-terminal domain BLOC1_2 PF10046.9 EEQ27460.1 - 0.089 13.1 0.9 2.4 8.5 0.3 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Type2_restr_D3 PF16902.5 EEQ27460.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Syntaxin PF00804.25 EEQ27460.1 - 0.15 11.7 0.8 0.29 10.8 0.2 1.6 2 0 0 2 2 2 0 Syntaxin DUF4404 PF14357.6 EEQ27460.1 - 0.16 12.6 0.4 0.43 11.2 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Syntaxin-6_N PF09177.11 EEQ27460.1 - 0.16 12.5 3.0 0.6 10.7 1.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Snapin_Pallidin PF14712.6 EEQ27460.1 - 0.18 12.3 0.8 11 6.5 0.5 2.6 2 1 0 2 2 2 0 Snapin/Pallidin Fmp27_WPPW PF10359.9 EEQ27460.1 - 0.2 10.4 0.1 0.28 10.0 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DASH_Duo1 PF08651.10 EEQ27460.1 - 0.4 10.5 1.4 33 4.4 0.0 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 TPR_MLP1_2 PF07926.12 EEQ27460.1 - 0.71 9.9 2.8 5.2 7.1 1.5 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EEQ27460.1 - 1.1 9.4 4.4 19 5.4 4.4 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TPT PF03151.16 EEQ27461.1 - 1.4e-22 80.4 25.4 1.9e-22 80.0 25.4 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EEQ27461.1 - 0.00099 18.4 24.1 0.0017 17.6 24.1 1.4 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EEQ27461.1 - 0.22 11.7 34.8 0.58 10.3 10.1 2.7 3 0 0 3 3 3 0 EamA-like transporter family TFIIB PF00382.19 EEQ27463.1 - 1.3e-30 105.3 0.4 4.1e-17 62.0 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EEQ27463.1 - 1.3e-25 89.6 0.0 1.3e-25 89.6 0.0 3.6 5 0 0 5 5 5 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EEQ27463.1 - 0.00012 21.5 2.7 0.00028 20.3 2.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EEQ27463.1 - 0.012 15.3 0.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Cyclin, N-terminal domain IBR PF01485.21 EEQ27463.1 - 0.65 10.3 2.5 1.3 9.3 2.5 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Stomagen PF16851.5 EEQ27464.1 - 0.092 12.8 0.3 0.16 12.0 0.3 1.3 1 0 0 1 1 1 0 Stomagen E1-E2_ATPase PF00122.20 EEQ27465.1 - 5.2e-51 172.7 0.1 5.5e-50 169.4 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 EEQ27465.1 - 3.7e-37 126.6 5.2 2.1e-10 40.9 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EEQ27465.1 - 1.9e-34 119.8 0.1 3.4e-34 119.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEQ27465.1 - 0.00016 21.5 1.7 0.0016 18.2 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEQ27465.1 - 0.018 15.4 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DAHP_snth_FXD PF18152.1 EEQ27465.1 - 0.049 13.5 0.3 38 4.2 0.1 3.7 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain Acyl_transf_1 PF00698.21 EEQ27465.1 - 2.9 7.3 5.7 3.7 7.0 0.1 2.9 3 0 0 3 3 3 0 Acyl transferase domain ERCC4 PF02732.15 EEQ27466.1 - 3.9e-27 95.4 0.1 6.2e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EEQ27466.1 - 0.0052 17.1 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain Zn_clus PF00172.18 EEQ27467.1 - 1.6e-06 28.2 10.5 2.3e-06 27.6 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ27467.1 - 8e-05 21.8 0.3 0.0002 20.5 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain PRP3 PF08572.10 EEQ27468.1 - 2.7e-74 249.7 3.9 5.1e-74 248.8 3.9 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EEQ27468.1 - 5.9e-48 162.7 0.9 5.9e-48 162.7 0.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.17 EEQ27469.1 - 1.1e-86 290.6 0.1 1.9e-86 289.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EEQ27469.1 - 3.7e-67 225.7 0.1 8.9e-67 224.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EEQ27469.1 - 5.6e-35 120.6 0.0 9e-34 116.7 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EEQ27469.1 - 3.2e-28 99.0 1.3 6.7e-27 94.6 1.1 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EEQ27469.1 - 1.7e-17 63.3 0.0 8.2e-17 61.1 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DEAD_2 PF06733.15 EEQ27470.1 - 3.3e-55 186.4 1.0 5.6e-55 185.7 0.2 1.8 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 EEQ27470.1 - 2.5e-48 164.3 3.6 2e-43 148.3 1.0 2.7 3 0 0 3 3 3 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EEQ27470.1 - 2.2e-44 151.6 0.0 7.2e-44 150.0 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EEQ27470.1 - 2.7e-06 27.5 0.1 7.5e-05 22.8 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEQ27470.1 - 0.00026 20.8 0.0 0.2 11.4 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase SNF2_N PF00176.23 EEQ27470.1 - 0.0023 16.7 0.0 0.017 13.9 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.6 EEQ27470.1 - 0.1 13.0 0.0 0.42 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EEQ27470.1 - 0.27 11.5 2.9 15 5.8 0.0 3.0 3 1 0 3 3 3 0 AAA domain AAA_11 PF13086.6 EEQ27470.1 - 5.1 6.8 6.7 1 9.1 1.2 2.4 2 1 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 EEQ27471.1 - 2.5e-07 30.9 12.0 5.8e-07 29.7 12.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EEQ27471.1 - 7.7e-05 22.7 3.8 0.00016 21.6 3.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EEQ27471.1 - 0.00031 21.0 10.6 0.00094 19.4 10.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain FANCL_C PF11793.8 EEQ27471.1 - 0.0022 18.1 7.2 0.005 17.0 7.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 EEQ27471.1 - 0.0033 17.3 13.4 0.0068 16.3 13.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ27471.1 - 0.011 15.5 11.0 0.029 14.2 11.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEQ27471.1 - 0.04 13.6 6.7 0.082 12.5 6.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EEQ27471.1 - 0.28 11.5 10.3 0.63 10.4 10.3 1.7 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.22 EEQ27471.1 - 0.8 9.6 8.4 0.24 11.3 5.3 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 EEQ27471.1 - 1.8 8.8 10.4 3.9 7.7 10.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 EEQ27471.1 - 5 7.1 7.9 12 5.8 7.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EEQ27471.1 - 5.1 7.0 8.1 10 6.0 8.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LCM PF04072.14 EEQ27472.1 - 3e-24 86.0 0.0 6.6e-24 84.9 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase SUN PF03856.13 EEQ27473.1 - 8.7e-79 264.4 11.5 1.4e-78 263.8 11.5 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) SR-25 PF10500.9 EEQ27473.1 - 4.7 6.7 24.6 9.2 5.8 24.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SOG2 PF10428.9 EEQ27473.1 - 6.5 5.8 18.5 8.6 5.4 18.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein zf-C3HC4_3 PF13920.6 EEQ27474.1 - 0.0034 17.2 2.5 1.1 9.2 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ27474.1 - 0.061 13.2 2.3 0.47 10.4 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 EEQ27474.1 - 0.095 13.4 1.8 6.1 7.6 0.1 2.5 2 0 0 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 EEQ27474.1 - 0.19 11.9 3.5 0.21 11.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger containing family Ist1 PF03398.14 EEQ27475.1 - 4.1e-27 95.1 1.0 1.6e-14 54.1 2.0 2.2 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway DUF3438 PF11920.8 EEQ27475.1 - 0.2 10.9 0.1 0.2 10.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3438) GEN1_C PF18380.1 EEQ27475.1 - 9.4 7.2 7.3 2.5 9.0 0.8 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain SfLAP PF11139.8 EEQ27476.1 - 0.0052 16.3 0.7 0.0052 16.3 0.7 2.0 3 0 0 3 3 3 1 Sap, sulfolipid-1-addressing protein Peptidase_S28 PF05577.12 EEQ27478.1 - 5e-52 177.2 1.0 8.4e-52 176.4 1.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DAHP_synth_2 PF01474.16 EEQ27479.1 - 4.6e-139 463.7 0.0 1.9e-81 273.8 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family Zn_clus PF00172.18 EEQ27480.1 - 5.6e-05 23.2 13.0 5.6e-05 23.2 13.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EEQ27480.1 - 0.04 14.4 6.3 0.12 12.9 6.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3630 PF12305.8 EEQ27480.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) AMP-binding PF00501.28 EEQ27481.1 - 7.6e-62 209.3 0.0 9.4e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ27481.1 - 8.8e-06 26.6 0.0 2.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IFT20 PF14931.6 EEQ27481.1 - 0.047 13.9 0.1 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Ste5_C PF12194.8 EEQ27481.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.5 1 1 0 1 1 1 0 Protein kinase Fus3-binding Clat_adaptor_s PF01217.20 EEQ27482.1 - 2e-54 183.4 2.3 2.4e-54 183.1 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.20 EEQ27484.1 - 1.4e-19 70.9 0.6 2.4e-19 70.1 0.6 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2711 PF10924.8 EEQ27484.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) TFIID-18kDa PF02269.16 EEQ27485.1 - 2.1e-30 104.6 0.4 2.3e-29 101.2 0.4 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Aminotran_1_2 PF00155.21 EEQ27486.1 - 4.8e-64 216.8 0.0 5.7e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEQ27486.1 - 0.054 12.0 0.0 0.094 11.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EEQ27486.1 - 0.081 11.9 0.0 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V Tam41_Mmp37 PF09139.11 EEQ27488.1 - 5.6e-131 436.8 0.0 6.7e-131 436.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial BIR PF00653.21 EEQ27489.1 - 1.3e-24 86.6 2.1 1.7e-22 79.9 0.1 3.2 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.8 EEQ27490.1 - 2.2e-08 34.2 0.4 4e-08 33.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ27490.1 - 9.3e-06 25.9 0.5 9.3e-06 25.9 0.5 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EEQ27490.1 - 0.0008 19.7 0.4 0.0016 18.8 0.4 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EEQ27490.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RNA_pol_Rpc4 PF05132.14 EEQ27490.1 - 2.1 8.7 5.0 11 6.4 0.6 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF1115 PF06544.12 EEQ27490.1 - 4.8 7.3 10.0 1.1 9.3 5.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) DUF3128 PF11326.8 EEQ27490.1 - 7.7 7.0 9.9 2.5 8.6 4.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) F-box-like PF12937.7 EEQ27491.1 - 6.9e-05 22.7 0.3 0.00012 21.9 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ27491.1 - 0.00053 19.8 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain AMP-binding PF00501.28 EEQ27492.1 - 2.5e-42 145.0 0.0 3.9e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ27492.1 - 0.0023 18.9 0.0 0.0052 17.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EEQ27492.1 - 0.045 13.7 0.2 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus Pkinase PF00069.25 EEQ27494.1 - 1.8e-20 73.5 0.0 8.9e-20 71.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27494.1 - 1e-05 25.0 0.2 0.00026 20.4 0.2 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase RNA_pol_Rpb5_C PF01191.19 EEQ27497.1 - 1.1e-33 115.0 0.1 1.7e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EEQ27497.1 - 4.1e-26 91.4 0.0 6.7e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EEQ27497.1 - 0.00031 20.8 0.0 0.00076 19.5 0.0 1.6 2 0 0 2 2 2 1 Restriction endonuclease DUF2968 PF11180.8 EEQ27498.1 - 0.00021 21.0 10.5 0.00021 21.0 10.5 4.4 2 1 1 4 4 4 2 Protein of unknown function (DUF2968) DUF4363 PF14276.6 EEQ27498.1 - 0.008 16.3 4.0 0.008 16.3 4.0 4.3 4 2 1 6 6 5 1 Domain of unknown function (DUF4363) APG6_N PF17675.1 EEQ27498.1 - 0.01 16.3 18.6 0.01 16.3 18.6 4.6 2 1 2 4 4 4 0 Apg6 coiled-coil region Helicase_IV_N PF12462.8 EEQ27498.1 - 0.081 12.9 0.1 0.081 12.9 0.1 3.4 2 1 0 3 3 3 0 DNA helicase IV / RNA helicase N terminal EzrA PF06160.12 EEQ27498.1 - 0.26 9.4 46.6 0.013 13.7 8.5 4.0 2 1 1 4 4 4 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 EEQ27498.1 - 0.37 11.0 36.0 0.057 13.6 7.1 4.4 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 EEQ27498.1 - 0.93 10.0 35.8 0.07 13.6 7.9 3.9 3 2 0 3 3 3 0 Spectrin repeat Golgin_A5 PF09787.9 EEQ27498.1 - 1.3 8.5 49.2 1.3 8.4 19.9 3.4 2 1 1 3 3 3 0 Golgin subfamily A member 5 DUF1664 PF07889.12 EEQ27498.1 - 2.6 8.1 23.8 1.6 8.8 3.8 4.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EEQ27498.1 - 3.7 7.6 18.2 1.3 9.1 3.5 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 EEQ27498.1 - 4.3 7.4 44.8 0.17 11.9 19.6 4.0 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PhoU PF01895.19 EEQ27498.1 - 6.8 7.2 14.6 3.3 8.2 1.4 3.9 3 1 0 3 3 3 0 PhoU domain Occludin_ELL PF07303.13 EEQ27498.1 - 8.6 7.1 37.6 0.96 10.2 3.0 4.8 2 1 3 5 5 5 0 Occludin homology domain CYSTM PF12734.7 EEQ27499.1 - 1.4e-14 54.1 11.8 1.4e-14 54.1 11.8 4.2 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 EEQ27499.1 - 0.24 12.0 9.1 0.32 11.6 9.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 EEQ27499.1 - 3.5 7.6 15.2 5 7.1 15.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Abhydrolase_3 PF07859.13 EEQ27501.1 - 2.5e-34 119.0 0.0 4.1e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltr_RsmB-F PF01189.17 EEQ27501.1 - 1.6e-15 57.3 0.0 8.2e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Thioesterase PF00975.20 EEQ27501.1 - 0.018 15.2 0.2 0.075 13.1 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain GAPES2 PF17156.4 EEQ27501.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain PLAC8 PF04749.17 EEQ27502.1 - 7.1e-14 52.6 2.1 1.7e-13 51.4 2.1 1.6 1 1 0 1 1 1 1 PLAC8 family Aldolase_II PF00596.21 EEQ27503.1 - 1e-45 156.0 0.1 1.3e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DEAD PF00270.29 EEQ27504.1 - 3.4e-43 147.4 0.1 5e-43 146.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ27504.1 - 4.3e-18 65.7 0.1 2e-17 63.5 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ27504.1 - 0.00012 22.1 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EEQ27504.1 - 0.037 13.3 0.2 0.074 12.3 0.2 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Ank_2 PF12796.7 EEQ27505.1 - 6.4e-28 97.2 18.2 2.9e-06 27.8 0.0 11.6 9 2 2 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ27505.1 - 5.8e-21 74.6 14.3 0.00074 20.0 0.0 13.4 12 3 1 13 13 13 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ27505.1 - 1.9e-11 43.1 15.5 13 6.8 0.0 15.1 19 0 0 19 19 19 3 Ankyrin repeat Ank PF00023.30 EEQ27505.1 - 1.1e-08 35.1 32.6 1.8 9.1 0.0 13.6 15 3 0 15 15 15 5 Ankyrin repeat Ank_5 PF13857.6 EEQ27505.1 - 4e-08 33.4 5.9 0.71 10.3 0.0 9.0 10 1 0 10 10 10 2 Ankyrin repeats (many copies) Adenylsucc_synt PF00709.21 EEQ27506.1 - 9.8e-170 565.0 0.0 1.1e-169 564.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.31 EEQ27507.1 - 3e-22 78.5 1.1 6.5e-22 77.4 1.1 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 EEQ27508.1 - 5.2e-27 94.5 0.0 2e-26 92.6 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ27508.1 - 3.7e-08 33.3 13.3 5.9e-08 32.7 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.11 EEQ27510.1 - 1.2e-15 57.1 0.2 3.8e-15 55.5 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.26 EEQ27510.1 - 0.00032 21.0 22.3 0.07 13.6 1.6 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type HTH_Tnp_Tc5 PF03221.16 EEQ27510.1 - 0.00054 19.9 0.0 0.0018 18.3 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 EEQ27510.1 - 0.00073 20.2 1.5 0.00073 20.2 1.5 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger Homeodomain PF00046.29 EEQ27510.1 - 0.0012 18.6 0.0 0.0037 17.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain Cupin_8 PF13621.6 EEQ27512.1 - 9.8e-33 113.9 0.0 2.4e-32 112.7 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EEQ27512.1 - 3.6e-06 26.7 0.0 0.0012 18.3 0.0 2.5 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.22 EEQ27512.1 - 0.025 15.0 0.0 0.061 13.8 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase PLA2_B PF01735.18 EEQ27512.1 - 0.082 11.3 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain 2OG-FeII_Oxy_2 PF13532.6 EEQ27513.1 - 2.5e-36 125.7 0.2 3.4e-36 125.3 0.2 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.16 EEQ27513.1 - 1.4e-05 24.6 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain zf-GRF PF06839.12 EEQ27513.1 - 0.00066 19.7 7.9 0.0013 18.8 7.9 1.5 1 0 0 1 1 1 1 GRF zinc finger MRP-S27 PF10037.9 EEQ27513.1 - 0.095 11.6 0.2 0.14 11.0 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 VWA PF00092.28 EEQ27514.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain UQ_con PF00179.26 EEQ27515.1 - 5.4e-10 39.1 0.0 9.2e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEQ27515.1 - 0.046 14.0 0.2 0.096 13.0 0.2 1.5 1 0 0 1 1 1 0 RWD domain DUF5314 PF17241.2 EEQ27515.1 - 0.14 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5314) GTP1_OBG PF01018.22 EEQ27516.1 - 1.7e-37 128.4 1.5 5.5e-27 94.3 3.4 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EEQ27516.1 - 3.7e-23 81.8 0.0 6.6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ27516.1 - 7.1e-08 32.1 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EEQ27516.1 - 0.041 12.9 0.0 0.63 9.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EEQ27516.1 - 0.062 13.8 1.4 0.15 12.6 0.1 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 EEQ27516.1 - 0.07 13.2 0.1 17 5.4 0.1 2.4 1 1 1 2 2 2 0 Dynamin family MFS_1 PF07690.16 EEQ27519.1 - 8.1e-35 120.4 12.8 3.3e-32 111.8 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ27519.1 - 9e-12 44.6 0.3 2e-11 43.5 0.3 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter Nuc_H_symport PF03825.16 EEQ27519.1 - 0.00071 18.7 1.1 0.00071 18.7 1.1 1.8 2 0 0 2 2 2 1 Nucleoside H+ symporter Abhydrolase_6 PF12697.7 EEQ27520.1 - 2.4e-13 51.2 6.6 7.9e-13 49.5 6.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.32 EEQ27521.1 - 2.3e-15 56.7 15.7 0.015 16.2 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF1518 PF07469.12 EEQ27521.1 - 0.11 12.9 3.8 0.31 11.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) Ccdc124 PF06244.12 EEQ27522.1 - 6.4e-29 101.1 23.6 1.4e-27 96.7 23.6 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 F-box-like PF12937.7 EEQ27523.1 - 2.8e-07 30.3 0.2 6.1e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ27523.1 - 6.1e-07 29.2 2.2 1.2e-06 28.2 0.5 2.5 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EEQ27523.1 - 0.0025 17.7 0.0 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box IZUMO PF15005.6 EEQ27523.1 - 2.3 8.8 3.9 2 8.9 1.0 2.3 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Peptidase_C13 PF01650.18 EEQ27524.1 - 6e-41 140.6 0.0 8.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family CDC45 PF02724.14 EEQ27525.1 - 2.2e-239 796.1 0.0 1.3e-238 793.5 0.0 2.6 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 EEQ27525.1 - 0.49 9.7 27.8 0.41 9.9 11.5 2.1 2 0 0 2 2 2 0 BUD22 SpoIIIAH PF12685.7 EEQ27525.1 - 2.2 8.0 8.9 2.5 7.9 2.4 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein SEEEED PF14797.6 EEQ27525.1 - 2.5 8.3 38.4 1 9.6 20.5 2.5 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Nop14 PF04147.12 EEQ27525.1 - 2.9 6.0 17.5 0.32 9.2 7.1 2.1 2 0 0 2 2 2 0 Nop14-like family CSRNP_N PF16019.5 EEQ27525.1 - 2.9 7.7 5.9 6.2 6.7 5.9 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DDRGK PF09756.9 EEQ27525.1 - 3.1 7.3 16.4 5.8 6.5 16.4 1.3 1 0 0 1 1 1 0 DDRGK domain FAM60A PF15396.6 EEQ27525.1 - 3.6 7.5 7.6 0.16 11.9 1.5 1.7 2 0 0 2 2 2 0 Protein Family FAM60A RR_TM4-6 PF06459.12 EEQ27525.1 - 4.2 7.1 9.0 0.34 10.7 3.9 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF572 PF04502.13 EEQ27525.1 - 8 6.0 15.1 0.91 9.1 8.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) NARP1 PF12569.8 EEQ27525.1 - 8.5 5.2 13.0 13 4.5 13.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ank_2 PF12796.7 EEQ27526.1 - 6.4e-118 385.6 0.2 1.7e-18 67.0 0.1 10.9 2 1 9 11 11 10 10 Ankyrin repeats (3 copies) Ank PF00023.30 EEQ27526.1 - 1.3e-89 291.0 11.7 6.4e-06 26.4 0.0 19.1 19 0 0 19 19 19 15 Ankyrin repeat Ank_3 PF13606.6 EEQ27526.1 - 1.7e-88 279.8 1.2 0.00032 20.9 0.0 18.8 18 0 0 18 18 18 17 Ankyrin repeat Ank_4 PF13637.6 EEQ27526.1 - 2.3e-88 289.5 3.8 1.3e-10 41.6 0.0 12.7 6 3 8 14 14 14 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ27526.1 - 2.8e-82 269.7 18.4 1.2e-07 31.8 0.0 15.6 3 3 13 16 16 16 16 Ankyrin repeats (many copies) NACHT PF05729.12 EEQ27526.1 - 3.5e-07 30.3 0.0 1.5e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EEQ27526.1 - 8.3e-07 29.5 0.0 2.7e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ27526.1 - 0.00037 20.8 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EEQ27526.1 - 0.00038 20.9 0.0 0.0017 18.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EEQ27526.1 - 0.0087 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EEQ27526.1 - 0.025 14.9 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEQ27526.1 - 0.026 15.0 0.0 0.16 12.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 EEQ27526.1 - 0.04 13.1 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain GATase_7 PF13537.6 EEQ27526.1 - 0.053 13.4 0.0 10 6.1 0.0 3.7 3 1 1 4 4 4 0 Glutamine amidotransferase domain cobW PF02492.19 EEQ27526.1 - 0.058 13.0 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EEQ27526.1 - 0.066 13.6 0.1 0.19 12.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.6 EEQ27526.1 - 0.099 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 EEQ27526.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase TsaE PF02367.17 EEQ27526.1 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EEQ27526.1 - 0.18 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 NTPase HeLo PF14479.6 EEQ27527.1 - 8.2e-48 163.0 1.5 1.2e-47 162.4 1.5 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Ses_B PF17046.5 EEQ27527.1 - 2.6e-08 33.6 3.0 6.8e-08 32.3 3.0 1.7 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein Adaptin_binding PF10199.9 EEQ27527.1 - 3.4 8.3 5.5 1.1 9.8 2.6 1.8 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 TPR_12 PF13424.6 EEQ27528.1 - 1.8e-21 76.2 0.9 1.5e-09 38.0 0.8 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ27528.1 - 2.6e-18 65.3 1.1 9.9e-09 34.8 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ27528.1 - 2.2e-10 40.4 1.3 8.5e-10 38.5 1.3 1.8 2 0 0 2 2 2 1 MalT-like TPR region Ses_B PF17046.5 EEQ27528.1 - 1.8e-08 34.1 2.2 3.7e-08 33.2 2.2 1.5 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein NB-ARC PF00931.22 EEQ27528.1 - 4.9e-08 32.5 0.0 3.7e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 EEQ27528.1 - 6.8e-06 26.1 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.6 EEQ27528.1 - 0.0025 17.9 4.8 0.17 12.1 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ27528.1 - 0.011 16.2 0.6 5.4 7.6 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ27528.1 - 0.032 14.3 0.2 6.8 7.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_25 PF13481.6 EEQ27528.1 - 0.033 13.8 0.0 0.091 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_4 PF07721.14 EEQ27528.1 - 0.035 14.7 3.5 9.7 7.1 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat UPF0240 PF06784.11 EEQ27528.1 - 0.077 13.0 0.6 2.9 7.9 0.5 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0240) Lpp-LpqN PF10738.9 EEQ27528.1 - 0.099 12.1 0.1 4.3 6.8 0.0 2.4 1 1 0 2 2 2 0 Probable lipoprotein LpqN AAA_22 PF13401.6 EEQ27528.1 - 0.11 12.7 0.0 0.43 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain TPR_1 PF00515.28 EEQ27528.1 - 0.12 12.3 1.3 9.3 6.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ27528.1 - 0.13 12.4 1.3 13 6.2 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Lzipper-MIP1 PF14389.6 EEQ27528.1 - 0.13 12.5 0.1 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 AAA_16 PF13191.6 EEQ27528.1 - 0.26 11.7 2.9 7.4 6.9 1.1 3.4 4 1 0 4 4 4 0 AAA ATPase domain DUF2508 PF10704.9 EEQ27528.1 - 0.68 10.1 5.0 22 5.3 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) Acetyltransf_7 PF13508.7 EEQ27529.1 - 4.6e-08 33.4 0.0 7.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ27529.1 - 1.1e-07 31.8 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ27529.1 - 5.4e-06 26.6 0.0 9.9e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EEQ27529.1 - 0.0035 17.3 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EEQ27529.1 - 0.1 12.7 0.1 16 5.6 0.0 2.6 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Ndufs5 PF10200.9 EEQ27531.1 - 0.014 15.6 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa AA_permease_2 PF13520.6 EEQ27532.1 - 1.3e-42 146.1 44.8 1.8e-42 145.7 44.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ27532.1 - 1.9e-21 76.2 42.4 1.1e-20 73.7 42.4 1.8 1 1 0 1 1 1 1 Amino acid permease YlaH PF14036.6 EEQ27532.1 - 0.004 17.5 2.3 0.004 17.5 2.3 2.3 2 0 0 2 2 2 1 YlaH-like protein CBM_19 PF03427.13 EEQ27532.1 - 0.08 12.9 0.6 0.25 11.3 0.6 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Acetyltransf_3 PF13302.7 EEQ27533.1 - 1.2e-16 61.6 0.0 2.2e-16 60.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ27533.1 - 1.1e-07 32.1 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EEQ27533.1 - 0.004 16.8 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ27533.1 - 0.0067 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EEQ27533.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_47 PF01532.20 EEQ27535.1 - 1.2e-140 469.5 0.0 1.3e-140 469.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Histidinol_dh PF00815.20 EEQ27537.1 - 1.6e-160 534.6 3.9 2.5e-160 534.0 3.9 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EEQ27537.1 - 5.4e-24 83.8 0.1 1.1e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EEQ27537.1 - 3.2e-14 53.1 0.0 2.1e-13 50.5 0.0 2.5 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EEQ27537.1 - 0.082 13.1 0.3 0.27 11.5 0.3 1.9 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Utp11 PF03998.13 EEQ27538.1 - 5.1e-56 190.3 23.3 6e-56 190.1 23.3 1.0 1 0 0 1 1 1 1 Utp11 protein GREB1 PF15782.5 EEQ27538.1 - 0.02 12.1 3.1 0.024 11.8 3.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CBP PF12192.8 EEQ27538.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal calcium binding protein Cmc1 PF08583.10 EEQ27539.1 - 5.4e-13 48.8 4.9 1.3e-12 47.6 4.9 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like TFIID-31kDa PF02291.15 EEQ27540.1 - 4.7e-45 152.6 0.0 6.3e-45 152.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.13 EEQ27541.1 - 1.9e-95 318.6 0.0 2.9e-95 318.0 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EEQ27541.1 - 2.6e-42 142.9 0.0 5.2e-42 141.9 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EEQ27541.1 - 0.018 14.7 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.21 EEQ27543.1 - 0.0018 18.6 0.0 0.005 17.2 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF4407 PF14362.6 EEQ27543.1 - 0.35 10.2 29.6 0.12 11.7 23.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 EEQ27543.1 - 1.2 9.7 53.2 0.077 13.5 7.7 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region Thg1 PF04446.12 EEQ27544.1 - 5.6e-53 178.2 0.1 9e-53 177.6 0.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EEQ27544.1 - 1.8e-51 173.4 5.1 2.4e-51 173.0 5.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Phage_sheath_1C PF17482.2 EEQ27544.1 - 0.017 15.1 0.2 0.9 9.5 0.1 2.6 2 1 0 2 2 2 0 Phage tail sheath C-terminal domain Ribosomal_L32p PF01783.23 EEQ27545.1 - 0.041 14.1 4.2 0.041 14.1 4.2 3.1 3 0 0 3 3 3 0 Ribosomal L32p protein family XRN_M PF17846.1 EEQ27545.1 - 8.1 5.3 28.2 3.9 6.3 18.2 2.0 2 0 0 2 2 2 0 Xrn1 helical domain RNA_pol_Rpb1_1 PF04997.12 EEQ27546.1 - 3.8e-112 374.7 0.0 6.2e-112 374.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EEQ27546.1 - 3e-105 351.5 0.0 5e-105 350.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EEQ27546.1 - 8.9e-75 250.5 0.0 2e-74 249.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EEQ27546.1 - 1.8e-66 223.6 1.1 3.3e-66 222.8 1.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EEQ27546.1 - 4e-47 160.1 0.0 9.5e-47 158.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EEQ27546.1 - 1e-44 151.8 7.9 1.5e-44 151.3 6.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EEQ27546.1 - 7.6e-38 128.8 0.2 1.6e-37 127.7 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EEQ27546.1 - 3.8e-16 58.5 204.6 0.0081 16.5 8.8 14.8 12 2 1 14 14 14 10 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.32 EEQ27547.1 - 8e-09 36.0 4.3 0.0034 18.2 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ27547.1 - 1.1e-06 28.8 0.5 0.0015 18.8 0.0 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_23 PF13489.6 EEQ27548.1 - 1.5e-16 60.7 0.0 2.1e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ27548.1 - 8.8e-09 36.0 0.0 2.7e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27548.1 - 6.2e-06 26.8 0.0 2.1e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ27548.1 - 3.9e-05 24.3 0.0 0.00012 22.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27548.1 - 4.4e-05 23.3 0.0 0.00012 21.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EEQ27548.1 - 0.00019 20.9 0.0 0.00045 19.7 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EEQ27548.1 - 0.00087 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EEQ27548.1 - 0.0021 17.4 0.0 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain FtsJ PF01728.19 EEQ27548.1 - 0.0023 18.1 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 EEQ27548.1 - 0.003 17.0 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EEQ27548.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 EEQ27548.1 - 0.061 12.6 0.0 0.71 9.2 0.0 2.3 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EEQ27548.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ALG11_N PF15924.5 EEQ27549.1 - 1.8e-82 276.5 0.0 2.4e-82 276.0 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EEQ27549.1 - 1.1e-17 64.1 0.0 3.6e-17 62.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEQ27549.1 - 4.9e-07 30.3 0.0 5.4e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEQ27549.1 - 0.036 14.1 0.0 0.071 13.1 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase Family 4 HemY_N PF07219.13 EEQ27549.1 - 0.072 13.3 0.5 0.27 11.4 0.5 1.9 1 0 0 1 1 1 0 HemY protein N-terminus 60KD_IMP PF02096.20 EEQ27550.1 - 2.1e-14 53.8 0.1 4.8e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 60Kd inner membrane protein DUF4817 PF16087.5 EEQ27550.1 - 0.063 13.1 0.1 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) PP2C PF00481.21 EEQ27551.1 - 9.3e-41 140.2 0.0 1.6e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EEQ27551.1 - 0.00035 20.3 0.0 0.00055 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EEQ27551.1 - 0.015 15.2 0.0 0.65 9.9 0.0 2.7 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.14 EEQ27552.1 - 1.9e-75 254.1 0.0 2.7e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_2 PF07719.17 EEQ27552.1 - 0.0021 18.0 0.0 0.099 12.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ27552.1 - 0.026 15.3 0.0 13 6.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ27552.1 - 0.081 12.8 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ27552.1 - 0.1 12.9 0.1 8.3 6.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Stm1_N PF09598.10 EEQ27552.1 - 1.2 10.0 13.3 0.18 12.7 7.7 2.6 2 0 0 2 2 2 0 Stm1 PQ-loop PF04193.14 EEQ27553.1 - 5.6e-39 131.7 6.1 6.1e-20 70.8 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EEQ27553.1 - 0.038 14.8 0.6 1.8 9.4 0.0 2.6 2 1 0 2 2 2 0 ER lumen protein retaining receptor PgaD PF13994.6 EEQ27553.1 - 0.051 13.6 2.4 2.7 8.0 1.2 2.5 2 1 0 2 2 2 0 PgaD-like protein Ribosomal_60s PF00428.19 EEQ27554.1 - 3e-26 91.8 6.2 3.8e-26 91.5 6.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.9 EEQ27555.1 - 9.6e-50 168.6 0.0 2e-29 102.9 0.0 4.3 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 EEQ27555.1 - 0.055 13.9 1.6 1.5 9.3 0.1 3.2 3 0 0 3 3 3 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 EEQ27555.1 - 0.071 13.2 0.5 0.28 11.2 0.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Aconitase PF00330.20 EEQ27556.1 - 1.8e-143 478.9 0.0 2.5e-143 478.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEQ27556.1 - 4.5e-41 140.2 0.0 7.3e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Importin_rep_4 PF18808.1 EEQ27557.1 - 3e-32 110.8 1.8 1.6e-31 108.4 0.8 2.9 2 0 0 2 2 2 1 Importin repeat Importin_rep_5 PF18816.1 EEQ27557.1 - 1.3e-22 79.8 0.7 8.5e-22 77.2 0.9 2.5 2 0 0 2 2 1 1 Importin repeat HEAT_EZ PF13513.6 EEQ27557.1 - 7e-21 74.3 11.1 2.6e-09 37.4 0.5 8.2 8 1 1 9 9 8 2 HEAT-like repeat HEAT_2 PF13646.6 EEQ27557.1 - 1.3e-20 73.5 6.2 3.9e-05 23.9 0.0 8.4 5 2 2 8 8 8 5 HEAT repeats HEAT PF02985.22 EEQ27557.1 - 5.1e-17 60.5 8.9 0.0023 18.0 0.0 10.7 11 0 0 11 11 9 4 HEAT repeat Importin_rep_6 PF18829.1 EEQ27557.1 - 2.4e-14 53.4 0.6 1.8e-13 50.6 0.1 2.8 2 0 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 EEQ27557.1 - 6.7e-10 39.4 0.0 0.027 15.1 0.0 6.1 3 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EEQ27557.1 - 1.8e-07 30.6 3.0 0.00062 19.0 0.1 4.9 5 2 1 6 6 6 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EEQ27557.1 - 2.2e-07 30.9 4.0 0.17 11.8 0.0 6.5 5 2 1 7 7 7 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 EEQ27557.1 - 3.5e-07 30.4 0.1 0.038 14.0 0.0 4.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EEQ27557.1 - 7.3e-07 29.0 0.1 0.14 11.7 0.0 5.5 5 1 1 6 6 5 1 CLASP N terminal DRIM PF07539.12 EEQ27557.1 - 2.3e-06 26.3 0.9 0.16 10.3 0.1 4.4 3 2 0 4 4 4 2 Down-regulated in metastasis RIX1 PF08167.12 EEQ27557.1 - 2.8e-06 27.2 0.1 0.01 15.6 0.0 4.6 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 EEQ27557.1 - 2.3e-05 24.5 0.1 0.13 12.5 0.1 5.0 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EEQ27557.1 - 5.2e-05 23.1 1.2 1.3 9.1 0.1 4.6 5 0 0 5 5 4 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EEQ27557.1 - 0.00024 19.8 1.5 0.0061 15.2 0.1 3.4 3 1 0 4 4 4 1 Adaptin N terminal region IBN_N PF03810.19 EEQ27557.1 - 0.0022 17.9 2.7 0.008 16.1 0.0 3.3 4 0 0 4 4 3 1 Importin-beta N-terminal domain Cnd3 PF12719.7 EEQ27557.1 - 0.014 14.6 2.2 1.8 7.7 0.0 4.6 4 1 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain DUF4042 PF13251.6 EEQ27557.1 - 0.016 14.9 2.2 13 5.4 0.0 5.0 6 0 0 6 6 5 0 Domain of unknown function (DUF4042) TFCD_C PF12612.8 EEQ27557.1 - 0.024 14.5 0.3 5.4 6.8 0.0 3.8 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal V-ATPase_H_N PF03224.14 EEQ27557.1 - 0.025 13.9 2.6 0.16 11.2 0.1 3.1 3 1 0 3 3 3 0 V-ATPase subunit H CBS PF00571.28 EEQ27558.1 - 2.1e-35 121.0 7.4 4.6e-09 36.6 0.0 5.8 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 EEQ27558.1 - 8.3e-10 38.5 0.1 3.5e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 PB1 domain Ribosomal_S26e PF01283.19 EEQ27559.1 - 4.6e-51 171.8 8.2 5.8e-51 171.5 8.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EEQ27559.1 - 0.02 14.9 0.6 0.042 13.8 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 EEQ27559.1 - 0.2 11.4 1.9 0.27 11.0 1.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) F-box-like PF12937.7 EEQ27560.1 - 0.00012 21.8 0.5 0.00038 20.3 0.5 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EEQ27560.1 - 0.001 18.9 1.8 0.39 10.9 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeat F-box_5 PF18511.1 EEQ27560.1 - 0.0024 17.4 0.3 0.0046 16.5 0.3 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 EEQ27560.1 - 0.15 12.0 2.1 0.18 11.7 0.4 2.0 2 0 0 2 2 2 0 F-box domain Peptidase_C14 PF00656.22 EEQ27562.1 - 1.9e-60 204.9 0.0 2.6e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Cpn60_TCP1 PF00118.24 EEQ27563.1 - 1.9e-153 511.6 5.7 2.2e-153 511.4 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 EEQ27563.1 - 0.054 13.9 0.1 13 6.3 0.0 2.7 2 0 0 2 2 2 0 Replication factor C C-terminal domain zf-H2C2 PF09337.10 EEQ27564.1 - 9.3e-16 57.8 2.3 1.8e-15 56.9 2.3 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EEQ27564.1 - 6.3e-10 39.0 0.4 6.3e-10 39.0 0.4 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain Ribo_biogen_C PF04034.13 EEQ27565.1 - 1.5e-50 170.2 0.0 2.2e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EEQ27565.1 - 2.3e-09 36.9 0.4 3.5e-09 36.3 0.4 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VHS PF00790.19 EEQ27567.1 - 1.5e-44 151.3 0.0 7e-44 149.1 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EEQ27567.1 - 2.6e-20 72.5 0.8 2.6e-20 72.5 0.8 3.1 4 0 0 4 4 4 1 GAT domain Alpha_adaptinC2 PF02883.20 EEQ27567.1 - 9.7e-19 67.7 0.5 9.7e-19 67.7 0.5 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 EEQ27567.1 - 1.5e-07 30.9 1.2 1.2e-06 28.0 0.1 2.7 2 0 0 2 2 2 1 GGA N-GAT domain Cir_Bir_Yir PF06022.11 EEQ27567.1 - 0.098 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir MCM PF00493.23 EEQ27569.1 - 1.8e-98 328.1 0.0 3.1e-98 327.4 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEQ27569.1 - 2.7e-39 133.9 0.1 4.9e-39 133.0 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EEQ27569.1 - 4.6e-27 95.2 29.3 4.6e-27 95.2 29.3 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EEQ27569.1 - 9.7e-24 83.6 0.2 3.2e-23 81.9 0.2 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ27569.1 - 8.6e-12 45.6 0.2 2.5e-11 44.1 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ27569.1 - 1.8e-07 30.8 0.1 9.7e-06 25.1 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ27569.1 - 6.6e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEQ27569.1 - 0.00061 19.6 0.0 0.0045 16.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEQ27569.1 - 0.0099 15.6 0.2 0.16 11.7 0.2 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 EEQ27569.1 - 0.14 11.8 0.4 0.32 10.7 0.4 1.5 1 0 0 1 1 1 0 AAA domain Na_H_Exchanger PF00999.21 EEQ27571.1 - 8.1e-06 24.9 13.5 0.00032 19.6 5.1 3.8 3 1 0 3 3 3 2 Sodium/hydrogen exchanger family Pkinase PF00069.25 EEQ27572.1 - 8.9e-65 218.7 0.0 1.1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27572.1 - 1.8e-30 106.1 0.0 2.6e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ27572.1 - 0.0019 17.2 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EEQ27572.1 - 0.12 12.3 0.1 0.61 10.0 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Zn_clus PF00172.18 EEQ27573.1 - 0.0004 20.4 7.4 0.00073 19.6 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 EEQ27574.1 - 3.4e-11 43.2 0.0 7.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ27574.1 - 2.1e-05 24.4 1.4 6.7e-05 22.7 1.3 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EEQ27574.1 - 0.0057 17.7 0.0 0.011 16.8 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UPF0126 PF03458.13 EEQ27574.1 - 0.089 12.7 0.6 0.17 11.8 0.6 1.5 1 0 0 1 1 1 0 UPF0126 domain DUF4627 PF15425.6 EEQ27575.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4627) UvdE PF03851.14 EEQ27576.1 - 1.4e-30 106.5 0.0 5.4e-21 75.0 0.0 2.1 2 0 0 2 2 2 2 UV-endonuclease UvdE AMP-binding PF00501.28 EEQ27577.1 - 4.8e-75 252.7 0.0 7.2e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EEQ27577.1 - 4e-71 239.6 0.0 7.7e-71 238.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EEQ27577.1 - 1.8e-53 181.9 0.0 2.9e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 EEQ27577.1 - 3.5e-52 176.9 0.1 2e-50 171.2 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EEQ27577.1 - 2.6e-47 161.5 0.0 4e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EEQ27577.1 - 4.9e-41 141.3 0.0 9.6e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ27577.1 - 2.4e-32 111.4 0.0 6.9e-32 109.9 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EEQ27577.1 - 1.4e-27 96.5 0.0 1.3e-26 93.3 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 EEQ27577.1 - 1.1e-19 71.0 0.0 9.3e-19 68.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EEQ27577.1 - 3.1e-16 59.8 0.0 1.3e-14 54.6 0.0 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EEQ27577.1 - 2.4e-15 56.6 0.3 3.9e-06 27.1 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EEQ27577.1 - 8.8e-12 45.6 0.0 3.9e-11 43.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EEQ27577.1 - 8.7e-11 41.7 0.0 2.1e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 EEQ27577.1 - 8e-10 38.8 0.0 2.3e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27577.1 - 6e-09 36.4 0.0 2.8e-08 34.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27577.1 - 3.2e-08 33.5 0.0 1.2e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EEQ27577.1 - 3.3e-08 33.2 0.2 1.1e-06 28.3 0.0 3.2 3 0 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.23 EEQ27577.1 - 2.2e-06 27.3 0.1 4.6e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 EEQ27577.1 - 5.9e-06 25.9 0.0 0.0096 15.3 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Ubie_methyltran PF01209.18 EEQ27577.1 - 1.4e-05 24.6 0.0 3.9e-05 23.1 0.0 1.7 2 0 0 2 2 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 EEQ27577.1 - 3.2e-05 23.6 0.0 0.00045 19.9 0.0 2.8 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 EEQ27577.1 - 0.0011 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Shikimate_DH PF01488.20 EEQ27577.1 - 0.013 15.6 0.0 0.87 9.6 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_33 PF10017.9 EEQ27577.1 - 0.016 14.3 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Sugar_tr PF00083.24 EEQ27578.1 - 2e-88 297.3 19.7 3e-88 296.7 19.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ27578.1 - 1.7e-32 112.7 45.2 4e-23 81.9 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EEQ27578.1 - 3.4e-06 26.6 3.2 3.4e-06 26.6 3.2 2.9 2 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EEQ27578.1 - 0.00074 17.9 1.8 0.00074 17.9 1.8 2.2 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MIS13 PF08202.11 EEQ27579.1 - 4.3e-15 55.8 24.5 2.4e-11 43.5 3.4 3.7 2 1 1 3 3 3 2 Mis12-Mtw1 protein family Trimer_CC PF08954.11 EEQ27579.1 - 0.059 12.9 1.4 0.19 11.3 0.1 2.6 2 0 0 2 2 2 0 Trimerisation motif DivIC PF04977.15 EEQ27579.1 - 0.093 12.5 0.1 0.31 10.8 0.1 1.9 1 0 0 1 1 1 0 Septum formation initiator EVI2A PF05399.11 EEQ27579.1 - 3.9 7.0 7.7 11 5.5 7.7 1.7 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) RPN7 PF10602.9 EEQ27580.1 - 2e-54 183.9 0.3 3.1e-54 183.3 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EEQ27580.1 - 1.5e-12 47.9 0.0 2.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain Aminotran_1_2 PF00155.21 EEQ27581.1 - 4.8e-40 137.8 0.0 6.6e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II TetR_C_14 PF17754.1 EEQ27581.1 - 0.059 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 MftR C-terminal domain PEPCK_ATP PF01293.20 EEQ27583.1 - 9e-218 723.6 0.0 1.1e-217 723.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EEQ27583.1 - 0.18 12.0 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 EEQ27585.1 - 1.1e-31 110.3 24.0 6.8e-21 74.6 5.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EEQ27585.1 - 8.5e-20 71.0 61.3 7.2e-19 67.9 37.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PEX11 PF05648.14 EEQ27586.1 - 2.4e-68 229.9 0.1 2.7e-68 229.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ATPase_gene1 PF09527.10 EEQ27586.1 - 0.041 14.1 0.3 0.098 12.8 0.3 1.7 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Amidase PF01425.21 EEQ27587.1 - 1.9e-71 241.4 0.1 2.2e-70 237.8 0.1 1.9 1 1 0 1 1 1 1 Amidase ARID PF01388.21 EEQ27588.1 - 1.7e-12 47.8 0.0 8.2e-12 45.6 0.0 2.3 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain DUF3328 PF11807.8 EEQ27588.1 - 0.0033 17.2 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DJ-1_PfpI PF01965.24 EEQ27589.1 - 2.9e-14 53.2 0.1 3.7e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family CysA_C_terminal PF17850.1 EEQ27589.1 - 0.12 12.9 0.1 0.51 11.0 0.0 2.1 2 0 0 2 2 2 0 CysA C-terminal regulatory domain GPI-anchored PF10342.9 EEQ27590.1 - 2.4e-12 47.5 0.5 4.9e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ArfGap PF01412.18 EEQ27591.1 - 2.2e-39 134.1 2.4 3.5e-39 133.5 2.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.18 EEQ27592.1 - 7.4e-50 168.1 0.1 9.5e-50 167.7 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EEQ27592.1 - 0.073 13.3 1.0 0.24 11.6 1.0 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 EEQ27592.1 - 0.089 12.8 1.3 4.5 7.4 0.1 2.3 2 1 0 2 2 2 0 Double zinc ribbon Zn_ribbon_recom PF13408.6 EEQ27592.1 - 1.3 9.6 4.2 22 5.6 0.4 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF1771 PF08590.10 EEQ27593.1 - 5.8e-12 45.8 5.5 1.6e-11 44.4 5.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 EEQ27593.1 - 4.1e-08 32.8 0.1 4.1e-08 32.8 0.1 3.1 4 0 0 4 4 4 1 CUE domain Smr PF01713.21 EEQ27593.1 - 0.00011 22.5 0.1 0.00034 20.9 0.1 1.9 1 0 0 1 1 1 1 Smr domain UBA PF00627.31 EEQ27593.1 - 0.037 14.0 1.7 0.14 12.1 0.0 2.6 3 0 0 3 3 3 0 UBA/TS-N domain Synaptobrevin PF00957.21 EEQ27594.1 - 0.43 10.4 3.7 2.5 8.0 0.4 2.1 1 1 1 2 2 2 0 Synaptobrevin EF_assoc_2 PF08356.12 EEQ27595.1 - 2.6e-34 117.1 0.0 4.9e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EEQ27595.1 - 2e-30 104.2 0.5 3.4e-30 103.5 0.5 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EEQ27595.1 - 1.3e-23 83.4 0.0 4.9e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EEQ27595.1 - 1.9e-13 50.7 0.0 5.1e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EEQ27595.1 - 1.4e-10 41.3 0.0 1.5e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_6 PF13405.6 EEQ27595.1 - 2.4e-07 30.1 0.5 0.031 14.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EEQ27595.1 - 3.6e-07 30.5 1.0 0.0012 19.3 0.2 3.0 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EEQ27595.1 - 7.9e-07 28.2 3.5 0.0061 16.0 0.1 3.0 3 0 0 3 3 2 2 EF hand AAA_16 PF13191.6 EEQ27595.1 - 1.1e-05 25.9 0.1 0.037 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EEQ27595.1 - 1.4e-05 24.7 0.2 0.011 15.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 EEQ27595.1 - 2.3e-05 24.5 1.0 0.16 12.0 0.0 3.3 3 1 1 4 4 3 2 Dynamin family EF-hand_10 PF14788.6 EEQ27595.1 - 0.00013 21.7 2.2 0.034 14.0 0.2 2.4 2 0 0 2 2 2 1 EF hand RsgA_GTPase PF03193.16 EEQ27595.1 - 0.00043 20.2 0.3 1.9 8.4 0.1 3.3 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EEQ27595.1 - 0.00045 20.5 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EEQ27595.1 - 0.0025 18.4 0.4 1.6 9.2 0.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EEQ27595.1 - 0.0025 18.1 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EEQ27595.1 - 0.0028 17.4 0.1 0.093 12.5 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EEQ27595.1 - 0.0037 17.8 0.0 2.4 8.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Ploopntkinase3 PF18751.1 EEQ27595.1 - 0.0066 16.4 0.0 0.68 9.8 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 EEQ27595.1 - 0.007 16.7 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EEQ27595.1 - 0.0082 15.9 0.1 0.54 9.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 EEQ27595.1 - 0.0099 15.4 0.0 19 4.8 0.0 3.2 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 EEQ27595.1 - 0.012 15.6 0.1 7.2 6.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EEQ27595.1 - 0.012 15.8 0.1 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EEQ27595.1 - 0.012 15.4 1.8 2.9 7.6 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Septin PF00735.18 EEQ27595.1 - 0.018 14.4 0.0 0.75 9.0 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 EEQ27595.1 - 0.018 14.6 0.1 4.1 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EEQ27595.1 - 0.023 14.0 0.3 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 EEQ27595.1 - 0.025 13.8 0.2 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SMC_N PF02463.19 EEQ27595.1 - 0.026 13.9 0.4 0.76 9.2 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MCM PF00493.23 EEQ27595.1 - 0.04 13.0 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 EEQ27595.1 - 0.054 13.0 0.1 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 EEQ27595.1 - 0.055 13.5 0.2 25 4.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) EF-hand_5 PF13202.6 EEQ27595.1 - 0.059 12.9 5.9 1.1 8.8 0.3 3.0 3 0 0 3 3 2 0 EF hand AAA PF00004.29 EEQ27595.1 - 0.12 12.8 0.3 12 6.4 0.0 2.9 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EEQ27595.1 - 0.18 12.3 0.1 12 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EEQ27595.1 - 0.19 11.0 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin EF-hand_8 PF13833.6 EEQ27595.1 - 0.27 11.1 0.7 19 5.2 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair IIGP PF05049.13 EEQ27595.1 - 0.34 9.9 0.7 2.8 6.9 0.1 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) cobW PF02492.19 EEQ27595.1 - 0.37 10.4 0.8 8.7 5.9 0.0 3.1 4 1 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain Ysc84 PF04366.12 EEQ27599.1 - 1.6e-42 144.2 0.4 5.8e-42 142.5 0.4 1.9 2 0 0 2 2 2 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EEQ27599.1 - 2.3e-13 49.5 0.1 1.1e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EEQ27599.1 - 2.4e-12 46.3 0.0 5.2e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EEQ27599.1 - 1e-11 44.5 0.0 4.3e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain DUF3104 PF11302.8 EEQ27599.1 - 0.078 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Zds_C PF08632.10 EEQ27600.1 - 2e-28 97.9 1.6 2e-28 97.9 1.6 1.7 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term ArAE_2_N PF10337.9 EEQ27602.1 - 2.2e-20 73.2 0.1 2.2e-20 73.2 0.1 2.1 3 0 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EEQ27602.1 - 3.8e-08 33.5 0.1 2.9e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EEQ27602.1 - 3e-06 27.4 8.0 3e-06 27.4 8.0 4.0 3 2 0 3 3 3 1 Fusaric acid resistance protein-like Miga PF10265.9 EEQ27602.1 - 0.027 13.5 0.4 0.045 12.7 0.4 1.2 1 0 0 1 1 1 0 Mitoguardin Lyase_aromatic PF00221.19 EEQ27602.1 - 0.15 10.7 0.7 1.4 7.5 0.1 2.2 2 0 0 2 2 2 0 Aromatic amino acid lyase Cation_efflux PF01545.21 EEQ27602.1 - 0.4 10.4 12.1 0.69 9.6 3.1 3.7 4 0 0 4 4 4 0 Cation efflux family ArAE_1 PF06081.11 EEQ27602.1 - 2.9 8.0 11.8 0.21 11.7 2.8 3.2 3 0 0 3 3 3 0 Aromatic acid exporter family member 1 ANAPC4_WD40 PF12894.7 EEQ27603.1 - 2.8e-13 50.0 0.0 3.2e-05 24.1 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ27603.1 - 2.9e-10 40.5 16.8 0.00018 22.2 0.3 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.12 EEQ27603.1 - 0.0015 16.6 0.0 0.0035 15.4 0.0 1.4 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.11 EEQ27603.1 - 0.0015 18.4 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EEQ27603.1 - 0.077 13.0 0.0 6.3 6.9 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EEQ27603.1 - 0.11 11.0 0.0 0.19 10.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Arf PF00025.21 EEQ27604.1 - 1.8e-73 245.7 0.1 2.2e-73 245.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EEQ27604.1 - 3.9e-14 52.9 0.0 5.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EEQ27604.1 - 8.6e-12 44.9 0.0 9.8e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EEQ27604.1 - 1.7e-11 43.9 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EEQ27604.1 - 2.6e-11 43.3 1.5 3e-07 29.9 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EEQ27604.1 - 2.6e-11 43.3 0.0 3.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EEQ27604.1 - 0.00016 21.7 0.0 0.00044 20.3 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EEQ27604.1 - 0.033 13.5 0.3 0.053 12.8 0.1 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Pyr_redox_3 PF13738.6 EEQ27605.1 - 1e-13 51.3 0.0 1.5e-12 47.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EEQ27605.1 - 1.1e-12 47.2 0.0 4.7e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EEQ27605.1 - 8.3e-11 41.6 0.0 1.1e-08 34.7 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ27605.1 - 3.2e-09 36.4 0.0 8.7e-07 28.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EEQ27605.1 - 5.8e-07 29.0 0.0 4.9e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EEQ27605.1 - 7e-06 25.6 0.1 0.027 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ27605.1 - 9.2e-06 25.8 0.4 0.00017 21.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ27605.1 - 1.3e-05 25.6 0.4 0.027 15.0 0.3 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ27605.1 - 0.00034 19.8 0.6 0.037 13.1 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EEQ27605.1 - 0.00051 20.1 0.0 0.1 12.6 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EEQ27605.1 - 0.024 13.7 2.9 1.1 8.3 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EEQ27605.1 - 0.027 14.1 0.6 0.18 11.3 0.0 2.6 4 0 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EEQ27605.1 - 0.029 14.8 0.0 0.69 10.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 EEQ27605.1 - 0.03 13.0 2.1 0.093 11.4 0.1 2.6 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 EEQ27605.1 - 0.11 11.6 2.6 0.43 9.6 0.4 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 EEQ27605.1 - 0.12 11.6 0.0 14 4.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF4147 PF13660.6 EEQ27605.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) F-box-like PF12937.7 EEQ27606.1 - 0.011 15.6 0.2 0.05 13.5 0.1 2.2 2 1 0 2 2 2 0 F-box-like Zn_clus PF00172.18 EEQ27607.1 - 2.6e-10 40.2 9.6 4e-10 39.6 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.18 EEQ27608.1 - 4.1e-23 80.6 1.4 1.2e-22 79.1 1.4 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain IMUP PF15761.5 EEQ27608.1 - 3.2 8.5 12.1 0.3 11.8 5.9 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Meiotic_rec114 PF03525.14 EEQ27610.1 - 4.4e-06 25.9 0.0 9.4e-06 24.8 0.0 1.5 1 0 0 1 1 1 1 Meiotic recombination protein rec114 Mito_carr PF00153.27 EEQ27611.1 - 1.3e-51 172.4 3.5 2.2e-16 59.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.11 EEQ27611.1 - 0.0024 17.8 1.3 0.0041 17.0 1.3 1.3 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus zf-Nse PF11789.8 EEQ27612.1 - 2.6e-21 75.2 0.6 4.7e-21 74.4 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EEQ27612.1 - 1.7e-05 24.7 0.1 9.5e-05 22.4 0.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EEQ27612.1 - 0.0036 17.1 0.6 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EEQ27612.1 - 0.0039 17.3 0.1 0.01 16.0 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-MIZ PF02891.20 EEQ27612.1 - 0.049 13.4 0.6 0.75 9.6 0.1 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Mpp10 PF04006.12 EEQ27612.1 - 0.052 12.0 27.3 0.0038 15.7 22.1 1.6 2 0 0 2 2 2 0 Mpp10 protein zf-C3HC4 PF00097.25 EEQ27612.1 - 0.084 12.8 0.4 0.42 10.5 0.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AGH PF17558.2 EEQ27612.1 - 2.9 8.1 6.3 0.68 10.1 0.1 2.8 3 0 0 3 3 3 0 Androgenic gland hormone Pox_MCEL PF03291.16 EEQ27613.1 - 2.6e-58 197.7 0.0 2.4e-40 138.6 0.0 4.1 2 2 1 3 3 3 3 mRNA capping enzyme Methyltransf_25 PF13649.6 EEQ27613.1 - 1.4e-09 38.6 0.0 0.0013 19.4 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ27613.1 - 3.2e-09 37.4 0.1 6.3e-08 33.3 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27613.1 - 1.7e-06 28.6 0.0 0.022 15.4 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27613.1 - 2.1e-05 24.3 0.0 0.079 12.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EEQ27613.1 - 0.00014 21.1 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 EEQ27613.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Hamartin PF04388.12 EEQ27613.1 - 8.1 5.0 12.1 11 4.5 12.1 1.1 1 0 0 1 1 1 0 Hamartin protein zf-C3HC PF07967.13 EEQ27614.1 - 5.9e-36 123.4 0.2 1e-35 122.7 0.2 1.4 1 0 0 1 1 1 1 C3HC zinc finger-like Rsm1 PF08600.10 EEQ27614.1 - 0.41 10.8 6.9 4.7 7.4 0.0 3.1 3 1 0 3 3 3 0 Rsm1-like MRI PF15325.6 EEQ27614.1 - 1.5 9.9 4.9 11 7.1 0.7 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection zf-CHY PF05495.12 EEQ27616.1 - 0.0062 17.0 0.4 0.0062 17.0 0.4 3.6 2 1 1 3 3 3 1 CHY zinc finger Rep_Org_C PF06926.11 EEQ27616.1 - 0.11 12.8 0.1 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus Polysacc_deac_1 PF01522.21 EEQ27617.1 - 1.3e-18 67.0 0.0 9.2e-18 64.3 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 EEQ27617.1 - 0.043 13.0 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF3295 PF11702.8 EEQ27619.1 - 3.7e-175 584.1 35.2 4.5e-175 583.8 35.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EEQ27619.1 - 1.2e-11 44.2 2.9 2.8e-11 43.0 2.9 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cpn60_TCP1 PF00118.24 EEQ27621.1 - 2.1e-158 528.0 4.0 2.4e-158 527.8 4.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 EEQ27621.1 - 0.066 13.4 2.6 10 6.3 0.1 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Chromo_shadow PF01393.19 EEQ27622.1 - 1.6e-18 66.5 0.0 3.7e-16 58.9 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EEQ27622.1 - 1e-11 44.5 0.2 4.5e-11 42.5 0.2 2.1 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Myc_N PF01056.18 EEQ27622.1 - 0.018 15.0 1.4 0.031 14.2 1.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Myb_DNA-bind_2 PF08914.11 EEQ27623.1 - 6e-22 77.6 3.0 2.9e-21 75.4 0.1 3.0 3 0 0 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.8 EEQ27623.1 - 1.2e-21 76.5 0.1 3e-19 68.9 0.0 2.6 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.10 EEQ27623.1 - 6.8e-08 33.1 0.4 0.0009 19.8 0.1 2.8 2 0 0 2 2 2 2 Rap1, DNA-binding DHHC PF01529.20 EEQ27624.1 - 2.3e-33 115.2 7.9 2.3e-33 115.2 7.9 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase Atx10homo_assoc PF09759.9 EEQ27625.1 - 4.4e-33 113.2 1.3 7e-33 112.6 0.3 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain IBR PF01485.21 EEQ27626.1 - 1.7e-07 31.4 22.0 7e-07 29.4 6.7 3.5 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EEQ27626.1 - 0.001 19.0 5.2 0.001 19.0 5.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EEQ27626.1 - 0.0021 17.9 6.8 0.0021 17.9 6.8 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ27626.1 - 0.0025 18.1 9.3 0.0025 18.1 9.3 3.7 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ27626.1 - 0.0098 15.7 4.9 0.0098 15.7 4.9 3.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 EEQ27626.1 - 3.5 8.0 11.9 0.18 12.1 0.6 3.3 3 0 0 3 3 3 0 zinc-ribbon zf-RING_2 PF13639.6 EEQ27627.1 - 1.2e-08 35.1 3.3 1.9e-08 34.5 3.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EEQ27627.1 - 8.8e-06 25.9 3.6 0.00013 22.1 3.6 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEQ27627.1 - 0.00019 21.4 5.9 0.00033 20.6 5.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EEQ27627.1 - 0.0017 18.4 0.6 0.0028 17.7 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EEQ27627.1 - 0.025 14.4 4.3 0.12 12.2 4.2 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEQ27627.1 - 0.042 13.6 2.9 0.071 12.9 2.9 1.4 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 EEQ27627.1 - 0.044 13.6 1.6 0.34 10.8 1.5 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 EEQ27627.1 - 0.06 13.6 0.2 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon Ndc80_HEC PF03801.13 EEQ27627.1 - 0.13 11.9 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family zf-C3HC4 PF00097.25 EEQ27627.1 - 0.24 11.3 1.2 0.47 10.4 1.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEQ27627.1 - 0.6 10.0 3.5 5.7 6.9 0.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Putative_PNPOx PF01243.20 EEQ27628.1 - 4.7e-10 39.5 0.0 7.6e-06 26.0 0.0 2.9 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 EEQ27628.1 - 4e-05 23.9 0.0 0.0024 18.2 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Bys1 PF04681.12 EEQ27630.1 - 9e-11 41.9 0.1 1.1e-10 41.7 0.1 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NTP_transferase PF00483.23 EEQ27631.1 - 9.2e-31 107.3 0.0 1.2e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EEQ27631.1 - 1e-08 34.6 7.4 4e-06 26.3 0.1 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EEQ27631.1 - 1.3e-08 35.3 0.0 2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EEQ27631.1 - 0.0098 15.6 0.0 0.033 13.9 0.0 1.7 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 EEQ27631.1 - 0.29 10.9 4.2 0.52 10.1 0.0 3.2 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.23 EEQ27632.1 - 6.4e-25 88.1 0.0 2.6e-24 86.2 0.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EEQ27632.1 - 1.3e-20 73.8 0.0 1.2e-15 57.5 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 EEQ27632.1 - 0.00042 20.4 0.2 0.0013 18.8 0.2 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EEQ27632.1 - 0.00094 19.2 0.0 0.016 15.3 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Syntaxin PF00804.25 EEQ27632.1 - 0.0043 16.8 0.6 0.74 9.5 0.1 2.7 3 0 0 3 3 3 1 Syntaxin Roc PF08477.13 EEQ27632.1 - 0.0094 16.2 0.0 0.045 14.0 0.0 2.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EEQ27632.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.6 EEQ27632.1 - 0.17 12.2 0.0 1 9.7 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain tRNA-synt_2 PF00152.20 EEQ27633.1 - 1.8e-77 260.5 0.5 2.4e-77 260.1 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ27633.1 - 1.4e-12 47.4 0.1 3.8e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EEQ27633.1 - 1.1e-05 25.1 0.0 0.017 14.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF1682 PF07946.14 EEQ27633.1 - 5.5 6.1 8.8 12 5.0 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-RanBP PF00641.18 EEQ27634.1 - 0.015 14.6 3.1 0.015 14.6 3.1 1.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-RING_4 PF14570.6 EEQ27634.1 - 0.12 12.1 4.2 0.26 11.1 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_2 PF14445.6 EEQ27634.1 - 0.18 12.0 6.4 0.33 11.1 6.4 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 COX15-CtaA PF02628.15 EEQ27635.1 - 1.4e-112 376.0 6.2 1.7e-112 375.7 6.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Glyoxalase PF00903.25 EEQ27636.1 - 1.3e-24 86.9 1.3 7.6e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EEQ27636.1 - 4e-14 52.8 0.4 3.2e-06 27.4 0.3 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EEQ27636.1 - 1.4e-07 31.8 0.1 0.0011 19.1 0.2 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EEQ27636.1 - 0.001 19.2 0.2 0.021 15.0 0.2 2.4 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF4844 PF16133.5 EEQ27636.1 - 0.027 15.0 0.1 0.14 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) TPR_17 PF13431.6 EEQ27637.1 - 5.5e-05 23.3 0.2 0.0041 17.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ27637.1 - 0.013 16.0 0.3 0.044 14.3 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HgmA PF04209.13 EEQ27638.1 - 1.1e-209 696.5 0.0 1.2e-209 696.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.18 EEQ27639.1 - 4.6e-55 186.6 0.0 6.2e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EEQ27639.1 - 1.7e-31 108.6 0.0 3.1e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_2 PF13409.6 EEQ27640.1 - 4.2e-11 43.0 0.0 9.5e-11 41.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EEQ27640.1 - 1.5e-10 41.2 0.0 3e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EEQ27640.1 - 6.1e-10 39.2 0.1 1.9e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EEQ27640.1 - 6e-09 36.2 0.0 9.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEQ27640.1 - 8.2e-08 32.4 0.1 2.7e-07 30.7 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ27640.1 - 0.00021 21.3 0.1 0.00052 20.0 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Oxidored_FMN PF00724.20 EEQ27643.1 - 1.5e-56 192.2 0.0 1.9e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family BATS PF06968.13 EEQ27644.1 - 3.4e-22 78.4 0.1 9.9e-22 76.9 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EEQ27644.1 - 1.5e-14 54.7 0.1 3.5e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Aminotran_3 PF00202.21 EEQ27645.1 - 3.6e-40 137.9 0.0 4.6e-22 78.2 0.0 2.4 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EEQ27645.1 - 5.5e-19 68.8 0.0 9.2e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.21 EEQ27646.1 - 4.4e-38 131.4 0.0 5.6e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ27646.1 - 0.0041 16.1 0.0 2.2 7.1 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EEQ27646.1 - 0.18 10.3 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GTP_EFTU PF00009.27 EEQ27647.1 - 2e-40 138.4 0.0 3.1e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEQ27647.1 - 3.1e-29 101.6 0.1 6.4e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEQ27647.1 - 1.6e-09 38.0 0.2 3.8e-09 36.8 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ27647.1 - 0.029 14.4 0.0 0.096 12.8 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase TFIIA PF03153.13 EEQ27647.1 - 3.6 7.5 27.3 6.6 6.6 27.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTP_transf_like PF01467.26 EEQ27648.1 - 1.5e-24 86.8 0.0 2.2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Ran-binding PF05508.11 EEQ27649.1 - 2.5e-94 315.8 5.9 5.5e-40 137.3 3.5 3.1 1 1 2 3 3 3 3 RanGTP-binding protein USP7_ICP0_bdg PF12436.8 EEQ27650.1 - 2.2e-39 135.2 0.0 4.2e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 EEQ27650.1 - 9.9e-37 126.8 0.3 1.7e-36 126.0 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ27650.1 - 2.3e-10 40.6 0.2 4.5e-09 36.3 0.2 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BSD PF03909.17 EEQ27651.1 - 2.1e-19 69.2 0.2 4.4e-19 68.2 0.2 1.6 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 EEQ27651.1 - 0.022 14.7 1.0 0.034 14.1 1.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Rad4 PF03835.15 EEQ27653.1 - 4.5e-36 123.8 0.0 9.1e-36 122.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EEQ27653.1 - 2.2e-27 95.3 0.1 4.7e-27 94.2 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EEQ27653.1 - 3.7e-20 71.5 0.0 8.3e-20 70.4 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EEQ27653.1 - 6.1e-16 59.1 0.8 6.1e-16 59.1 0.8 2.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Filament PF00038.21 EEQ27654.1 - 0.0016 18.1 161.9 0.11 12.1 52.4 6.5 2 1 4 6 6 6 5 Intermediate filament protein Pox_A_type_inc PF04508.12 EEQ27654.1 - 0.0018 18.0 5.1 11 6.0 0.0 7.3 6 0 0 6 6 6 1 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 EEQ27654.1 - 0.0027 17.7 22.2 0.0027 17.7 22.2 10.0 2 1 8 10 10 10 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myb_DNA-binding PF00249.31 EEQ27655.1 - 0.087 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3682 PF12446.8 EEQ27655.1 - 2.1 8.8 11.5 0.74 10.3 3.2 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3682) PTPA PF03095.15 EEQ27656.1 - 1.5e-108 362.8 0.0 1.7e-108 362.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.13 EEQ27657.1 - 2.2e-68 231.4 0.1 2.7e-68 231.1 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Glyco_hydro_3_C PF01915.22 EEQ27657.1 - 1.3e-46 159.1 0.0 2.4e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EEQ27657.1 - 2.9e-27 95.9 0.0 5.2e-23 81.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EEQ27657.1 - 1.4e-15 57.2 0.0 3e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PGC7_Stella PF15549.6 EEQ27657.1 - 6.1 6.8 6.1 4.3 7.3 1.5 2.2 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain PNP_UDP_1 PF01048.20 EEQ27658.1 - 2.4e-39 135.0 0.0 3e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2757 PF10955.8 EEQ27658.1 - 0.12 12.6 0.2 0.3 11.4 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) BUD22 PF09073.10 EEQ27659.1 - 1.3e-104 350.9 21.7 2.1e-104 350.3 21.7 1.3 1 0 0 1 1 1 1 BUD22 SIS PF01380.22 EEQ27660.1 - 1.1e-13 51.1 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 EEQ27660.1 - 4.2e-05 23.6 0.0 9.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 SIS domain DUF4726 PF15855.5 EEQ27661.1 - 0.051 13.8 0.1 0.075 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) Ubie_methyltran PF01209.18 EEQ27662.1 - 3.8e-78 262.0 0.0 9.5e-78 260.7 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EEQ27662.1 - 7.1e-16 58.7 0.0 1.4e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27662.1 - 1.6e-14 54.3 0.0 3.7e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27662.1 - 6.7e-12 45.4 0.0 8.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ27662.1 - 5.4e-10 39.9 0.0 9.1e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ27662.1 - 1.7e-06 27.9 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EEQ27662.1 - 0.033 14.0 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase E1_dh PF00676.20 EEQ27663.1 - 3.7e-91 305.2 0.2 4.7e-91 304.9 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EEQ27663.1 - 0.0011 18.8 0.1 0.0032 17.3 0.1 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EEQ27663.1 - 0.027 13.7 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 EEQ27663.1 - 0.047 12.5 0.0 0.15 10.8 0.0 1.8 2 0 0 2 2 2 0 XFP N-terminal domain zf-RING_4 PF14570.6 EEQ27664.1 - 2.2e-19 69.0 13.3 4.2e-19 68.1 13.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EEQ27664.1 - 2.6e-06 27.2 7.9 4.5e-06 26.4 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 EEQ27664.1 - 0.00019 21.2 0.0 0.00047 19.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 EEQ27664.1 - 0.00088 19.6 11.3 0.0017 18.7 11.3 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 EEQ27664.1 - 0.0021 18.0 5.0 0.0044 17.0 5.0 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 EEQ27664.1 - 0.17 11.8 9.4 1.4 8.9 9.8 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EEQ27664.1 - 0.23 11.4 12.7 0.45 10.4 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 EEQ27664.1 - 1.2 9.3 4.9 2.6 8.2 4.9 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.6 EEQ27664.1 - 5 7.2 10.8 11 6.1 10.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 EEQ27664.1 - 7 6.8 9.5 34 4.6 9.9 1.9 1 1 1 2 2 2 0 Double zinc ribbon Complex1_30kDa PF00329.19 EEQ27665.1 - 1.9e-45 154.4 0.0 2.8e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Myb_DNA-binding PF00249.31 EEQ27667.1 - 1.7e-05 24.9 0.2 1.7e-05 24.9 0.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ27667.1 - 0.0016 18.6 2.1 0.0092 16.2 0.5 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EEQ27667.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EEQ27667.1 - 0.04 14.1 0.1 0.074 13.2 0.1 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Rz1 PF06085.11 EEQ27668.1 - 0.053 13.3 1.1 0.2 11.4 1.1 2.0 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor AA_permease_2 PF13520.6 EEQ27669.1 - 7.7e-88 295.2 31.4 9.2e-88 294.9 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease PsbN PF02468.15 EEQ27669.1 - 2.2 8.2 6.1 0.54 10.1 1.6 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) p450 PF00067.22 EEQ27670.1 - 7.4e-44 150.2 0.0 4.6e-33 114.7 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 BolA PF01722.18 EEQ27670.1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 BolA-like protein FMO-like PF00743.19 EEQ27671.1 - 2.9e-90 303.2 0.0 3.8e-89 299.5 0.0 1.9 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EEQ27671.1 - 2.4e-13 50.0 0.0 6.4e-11 42.0 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ27671.1 - 7.1e-11 41.9 0.0 1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ27671.1 - 1.1e-09 37.9 0.0 2.2e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EEQ27671.1 - 3.8e-06 27.0 0.0 9.9e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ27671.1 - 6.8e-05 23.3 0.4 0.081 13.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ27671.1 - 9e-05 22.5 0.1 0.024 14.6 0.1 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EEQ27671.1 - 0.00098 18.8 0.7 0.038 13.6 0.4 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase F420_oxidored PF03807.17 EEQ27671.1 - 0.29 11.8 1.2 35 5.1 0.1 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_3 PF07859.13 EEQ27672.1 - 1.7e-62 211.0 0.4 2.6e-62 210.4 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ27672.1 - 3.5e-05 23.4 0.0 0.0031 17.0 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EEQ27672.1 - 0.00015 20.8 0.4 0.00054 19.0 0.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EEQ27672.1 - 0.0022 18.6 8.0 0.0053 17.4 6.9 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 EEQ27672.1 - 0.048 13.1 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Lyase_1 PF00206.20 EEQ27673.1 - 3.2e-112 375.0 0.0 4.4e-112 374.5 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EEQ27673.1 - 8.9e-21 74.1 0.0 2.3e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.12 EEQ27673.1 - 0.12 12.2 0.0 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Acetyltransf_1 PF00583.25 EEQ27675.1 - 1.3e-11 44.8 0.1 1.8e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ27675.1 - 2e-07 31.0 0.0 3.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ27675.1 - 2.2e-06 28.0 0.2 3.7e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Thiolase_C PF02803.18 EEQ27675.1 - 0.11 12.2 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Thiolase, C-terminal domain Ribosomal_L24e PF01246.20 EEQ27676.1 - 5.1e-29 100.3 0.1 5.1e-29 100.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e UQ_con PF00179.26 EEQ27677.1 - 2.3e-47 160.2 0.0 2.5e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ27677.1 - 0.0022 17.7 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EEQ27677.1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 EEQ27677.1 - 0.02 15.2 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Zn_ribbon_17 PF17120.5 EEQ27678.1 - 2.5e-07 30.2 18.6 2.5e-07 30.2 18.6 2.8 3 1 0 3 3 3 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EEQ27678.1 - 1.4e-06 28.9 23.7 0.0032 18.3 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat zf-RING_2 PF13639.6 EEQ27678.1 - 0.0058 16.9 10.0 0.019 15.3 10.0 2.0 1 0 0 1 1 1 1 Ring finger domain 4HBT PF03061.22 EEQ27680.1 - 7e-09 35.9 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EEQ27680.1 - 0.00068 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) UCH PF00443.29 EEQ27681.1 - 5.8e-49 166.9 0.5 7.5e-49 166.5 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ27681.1 - 1.3e-11 44.7 8.6 3.3e-11 43.4 8.6 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EEQ27681.1 - 8.6e-11 41.4 0.0 2.2e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EEQ27681.1 - 0.11 12.9 0.0 0.74 10.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain ARPC4 PF05856.12 EEQ27682.1 - 6.2e-78 260.2 3.1 7.1e-78 260.0 3.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) TYW3 PF02676.14 EEQ27684.1 - 4.4e-71 238.6 0.0 5.4e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2461 PF09365.10 EEQ27685.1 - 1.9e-62 210.9 0.2 3.1e-62 210.2 0.2 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) HSA PF07529.13 EEQ27687.1 - 0.088 13.1 0.0 0.088 13.1 0.0 3.1 2 1 1 3 3 3 0 HSA Eapp_C PF10238.9 EEQ27687.1 - 0.3 11.2 2.5 0.3 11.2 1.8 1.3 1 1 0 1 1 1 0 E2F-associated phosphoprotein DDRGK PF09756.9 EEQ27687.1 - 6.1 6.4 14.9 1.2 8.7 11.8 1.4 2 0 0 2 2 2 0 DDRGK domain Zn_clus PF00172.18 EEQ27688.1 - 9.1e-09 35.3 7.3 1.3e-08 34.8 7.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EEQ27689.1 - 1.6e-64 217.8 0.0 2.7e-63 213.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27689.1 - 3.8e-31 108.3 0.0 1.4e-29 103.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 EEQ27689.1 - 8.9e-31 106.1 0.2 2.1e-30 104.8 0.2 1.7 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Haspin_kinase PF12330.8 EEQ27689.1 - 0.00046 19.2 0.0 0.0021 17.1 0.0 2.1 2 1 1 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 EEQ27689.1 - 0.002 17.5 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ27689.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ27689.1 - 0.49 10.3 1.5 0.78 9.6 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF1690 PF07956.11 EEQ27690.1 - 2.4e-40 138.2 4.0 6.1e-20 72.1 1.4 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.6 EEQ27690.1 - 0.012 15.7 0.7 0.11 12.5 0.2 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Phasin PF05597.11 EEQ27690.1 - 0.15 12.1 1.4 0.45 10.5 0.3 2.1 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) POP1 PF06978.11 EEQ27691.1 - 3.7e-74 249.2 15.5 3.7e-74 249.2 15.5 2.4 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EEQ27691.1 - 4.8e-33 113.4 2.1 4.8e-33 113.4 2.1 2.7 2 0 0 2 2 2 1 POPLD (NUC188) domain Redoxin PF08534.10 EEQ27692.1 - 9.1e-39 132.5 0.0 1e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EEQ27692.1 - 9e-13 48.2 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Hexokinase_2 PF03727.16 EEQ27693.1 - 2.2e-74 249.9 0.0 3.1e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EEQ27693.1 - 7.3e-72 241.5 0.0 1e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 EEQ27693.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Gly-zipper_Omp PF13488.6 EEQ27693.1 - 0.31 11.1 5.6 1.6 8.8 1.3 2.6 2 0 0 2 2 2 0 Glycine zipper zf-C2HC5 PF06221.13 EEQ27694.1 - 1.3e-20 73.1 6.1 2e-20 72.5 6.1 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Tropomodulin PF03250.14 EEQ27694.1 - 0.77 9.8 7.3 5.4 7.1 2.6 2.6 1 1 1 2 2 2 0 Tropomodulin Phospholip_A2_3 PF09056.11 EEQ27695.1 - 5.9e-41 139.6 5.7 7e-41 139.3 5.7 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 DUF604 PF04646.12 EEQ27696.1 - 1.3e-08 34.6 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EEQ27696.1 - 0.0012 18.3 0.0 0.0029 17.1 0.0 1.5 1 1 0 1 1 1 1 Fringe-like GDI PF00996.18 EEQ27697.1 - 2.1e-25 89.2 0.0 5e-24 84.6 0.0 2.0 1 1 0 1 1 1 1 GDP dissociation inhibitor Pro_isomerase PF00160.21 EEQ27698.1 - 8.1e-47 159.4 0.0 9.7e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 EEQ27699.1 - 1.8e-60 204.9 0.1 4.5e-60 203.6 0.1 1.6 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EEQ27699.1 - 0.00064 19.3 6.4 0.00064 19.3 6.4 2.3 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease DUF2955 PF11168.8 EEQ27699.1 - 2.9 7.8 10.0 1.8 8.4 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) RNase_PH PF01138.21 EEQ27700.1 - 2.9e-17 63.4 1.5 1.8e-15 57.6 1.5 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_binding_6 PF08030.12 EEQ27701.1 - 8.2e-21 74.7 0.0 3.8e-20 72.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EEQ27701.1 - 1.3e-17 64.0 8.8 4.6e-17 62.3 8.8 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EEQ27701.1 - 1.5e-14 54.0 0.0 6.2e-14 52.0 0.0 2.1 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EEQ27701.1 - 0.0045 17.6 0.0 3.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 EEQ27701.1 - 0.025 15.1 1.1 0.025 15.1 1.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Acetyltransf_1 PF00583.25 EEQ27702.1 - 0.00084 19.6 0.0 0.04 14.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ27702.1 - 0.0065 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ27702.1 - 0.071 13.0 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EEQ27702.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sgf11 PF08209.11 EEQ27703.1 - 1.1e-07 31.3 1.7 7.8e-07 28.6 0.1 2.3 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) PGPGW PF09656.10 EEQ27704.1 - 1.7 8.2 5.8 0.36 10.4 0.3 2.2 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) SRF-TF PF00319.18 EEQ27705.1 - 3.4e-21 74.5 0.1 5e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Fungal_trans_2 PF11951.8 EEQ27706.1 - 3.8e-06 26.0 0.1 5.3e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactonase PF10282.9 EEQ27707.1 - 3.1e-85 286.4 0.0 3.9e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Phage_ASH PF10554.9 EEQ27707.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 2 0 0 2 2 2 0 Ash protein family Mg_trans_NIPA PF05653.14 EEQ27708.1 - 3.5e-14 52.6 10.7 4.7e-08 32.5 2.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EEQ27708.1 - 7.2e-06 26.2 0.8 7.2e-06 26.2 0.8 2.9 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EEQ27708.1 - 0.00012 21.4 0.1 0.00012 21.4 0.1 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 EEQ27708.1 - 0.0032 16.7 0.4 0.0058 15.9 0.4 1.3 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 EEQ27708.1 - 0.02 15.6 5.2 0.23 12.1 0.1 2.7 2 0 0 2 2 2 0 Small Multidrug Resistance protein TMEM61 PF15105.6 EEQ27708.1 - 0.034 14.0 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 TMEM61 protein family vATP-synt_E PF01991.18 EEQ27709.1 - 4.7e-60 202.4 11.8 5.4e-60 202.2 11.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.6 EEQ27709.1 - 0.0064 16.9 4.0 8.6 6.8 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4288) M11L PF11099.8 EEQ27710.1 - 0.21 11.8 0.0 0.41 10.9 0.0 1.4 1 0 0 1 1 1 0 Apoptosis regulator M11L like PhoLip_ATPase_C PF16212.5 EEQ27712.1 - 5.1e-79 265.5 17.5 5.1e-79 265.5 17.5 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEQ27712.1 - 1.6e-18 66.1 1.5 1.6e-18 66.1 1.5 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EEQ27712.1 - 6.5e-12 45.4 0.0 3.2e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEQ27712.1 - 2.1e-09 38.0 3.1 0.00016 22.1 0.6 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEQ27712.1 - 9.8e-05 22.0 0.0 0.00029 20.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EEQ27712.1 - 0.033 13.9 0.2 0.079 12.7 0.2 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SEN1_N PF12726.7 EEQ27713.1 - 2.2e-99 333.7 0.1 2.7e-99 333.4 0.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EEQ27714.1 - 2.1e-71 240.8 2.6 2.1e-71 240.8 2.6 2.8 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 EEQ27714.1 - 5.9e-59 199.0 0.0 1.1e-58 198.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.7 EEQ27714.1 - 8.7e-51 173.0 3.2 1.2e-50 172.5 3.2 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_30 PF13604.6 EEQ27714.1 - 3.3e-09 36.7 0.0 1.6e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EEQ27714.1 - 5e-08 33.0 0.0 0.0093 15.7 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EEQ27714.1 - 7.7e-08 32.8 0.0 3.4e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EEQ27714.1 - 1.4e-07 31.3 0.1 2e-05 24.3 0.1 2.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain zf-CCHC PF00098.23 EEQ27714.1 - 0.00053 19.9 1.4 0.00053 19.9 1.4 3.8 4 0 0 4 4 3 2 Zinc knuckle DEAD PF00270.29 EEQ27714.1 - 0.0023 17.7 0.2 0.0069 16.2 0.0 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 EEQ27714.1 - 0.029 13.4 0.1 0.099 11.7 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 EEQ27714.1 - 0.037 14.0 0.0 0.19 11.7 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCHC_5 PF14787.6 EEQ27714.1 - 0.41 10.4 13.2 1.1 9.1 0.1 3.2 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger DUF4164 PF13747.6 EEQ27714.1 - 0.81 10.0 4.8 2.7 8.3 4.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) CAP59_mtransfer PF11735.8 EEQ27716.1 - 1.2e-70 237.9 0.0 1.6e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CorA PF01544.18 EEQ27718.1 - 3.4e-09 36.4 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ApoL PF05461.11 EEQ27718.1 - 0.075 12.4 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Apolipoprotein L Pkinase PF00069.25 EEQ27719.1 - 2.4e-19 69.7 0.0 1.7e-17 63.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27719.1 - 1.4e-06 27.8 0.0 0.00023 20.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ27719.1 - 0.011 14.5 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EEQ27719.1 - 0.13 12.2 0.2 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family WH1 PF00568.23 EEQ27720.1 - 1.2e-28 99.2 0.0 1.8e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EEQ27720.1 - 0.0012 18.6 0.1 0.0038 17.0 0.1 1.9 1 0 0 1 1 1 1 WH2 motif eIF-1a PF01176.19 EEQ27722.1 - 4.7e-22 77.6 0.0 6.6e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.15 EEQ27723.1 - 2.5e-18 66.8 0.0 1.1e-17 64.7 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain fn3_2 PF16893.5 EEQ27724.1 - 6.2e-38 128.8 0.1 1.1e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EEQ27724.1 - 7.3e-24 83.5 0.5 1.4e-23 82.5 0.5 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EEQ27724.1 - 1.1e-13 50.9 0.0 2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EEQ27724.1 - 5.1e-07 30.0 0.0 8.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 EEQ27724.1 - 9.7e-06 25.7 0.2 4.4e-05 23.6 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 EEQ27724.1 - 0.00017 21.9 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 EEQ27724.1 - 0.0022 18.3 0.0 0.0089 16.4 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain Peptidase_S10 PF00450.22 EEQ27725.1 - 1e-73 249.2 0.0 1.6e-73 248.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_7 PF13508.7 EEQ27726.1 - 0.00036 20.9 0.0 0.00077 19.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ27726.1 - 0.00045 20.4 0.0 0.00075 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EEQ27726.1 - 0.0068 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EEQ27726.1 - 0.018 15.0 0.1 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase FR47 PF08445.10 EEQ27726.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.7 EEQ27726.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EEQ27726.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase SRPRB PF09439.10 EEQ27726.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Acetyltransf_10 PF13673.7 EEQ27727.1 - 8e-08 32.3 0.0 2.1e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ27727.1 - 5.8e-07 29.8 0.0 8.8e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ27727.1 - 3.7e-06 27.2 0.0 5.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EEQ27727.1 - 0.0021 18.2 0.0 0.026 14.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Porphobil_deam PF01379.20 EEQ27728.1 - 4.6e-72 241.8 0.0 6.5e-72 241.3 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EEQ27728.1 - 6.9e-21 74.4 0.1 1.2e-20 73.7 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GFA PF04828.14 EEQ27729.1 - 3.9e-10 39.9 1.7 0.00018 21.8 0.2 2.4 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 EEQ27729.1 - 0.022 14.9 0.7 0.055 13.6 0.7 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 EEQ27729.1 - 0.59 9.9 3.2 0.46 10.3 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain MFS_1 PF07690.16 EEQ27730.1 - 5.4e-45 153.9 37.5 5.4e-45 153.9 37.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ27730.1 - 1.1e-10 41.1 9.0 1.1e-10 41.1 9.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2583 PF10762.9 EEQ27730.1 - 1.8 9.0 7.2 0.13 12.7 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) OATP PF03137.20 EEQ27730.1 - 9.8 4.3 9.4 1.7 6.9 2.3 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 EEQ27731.1 - 5.4e-18 65.0 50.0 2.3e-15 56.4 31.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Evr1_Alr PF04777.13 EEQ27732.1 - 3e-25 88.6 0.0 5e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family R3H PF01424.22 EEQ27734.1 - 3.2e-12 46.2 0.0 1.6e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.17 EEQ27734.1 - 3.2e-05 23.9 73.6 0.00072 19.6 14.5 14.8 14 2 1 15 15 15 6 NF-X1 type zinc finger Pkinase PF00069.25 EEQ27735.1 - 0.0024 17.3 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.11 EEQ27735.1 - 0.027 13.4 0.1 0.033 13.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ARID PF01388.21 EEQ27737.1 - 3.3e-19 69.3 3.0 2.5e-18 66.5 0.0 2.5 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Cnd2 PF05786.14 EEQ27737.1 - 0.00014 20.7 0.3 0.00014 20.7 0.3 1.8 1 1 1 2 2 2 1 Condensin complex subunit 2 Presenilin PF01080.17 EEQ27737.1 - 0.027 13.3 11.2 0.046 12.5 11.2 1.3 1 0 0 1 1 1 0 Presenilin BAF250_C PF12031.8 EEQ27737.1 - 0.4 9.9 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa GREB1 PF15782.5 EEQ27737.1 - 4.9 4.1 15.0 7.6 3.5 15.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer YjbH PF06082.11 EEQ27737.1 - 9.4 4.9 15.3 15 4.2 15.3 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Img2 PF05046.14 EEQ27738.1 - 5.6e-26 90.7 0.0 8.3e-26 90.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 EEQ27739.1 - 1.5e-48 164.6 3.1 3.8e-48 163.3 3.1 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EEQ27739.1 - 4.3e-14 52.9 0.0 1.4e-13 51.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain DUF2564 PF10819.8 EEQ27739.1 - 0.026 14.9 0.1 2.7 8.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) HD_3 PF13023.6 EEQ27739.1 - 0.037 13.9 1.0 0.08 12.9 1.0 1.5 1 0 0 1 1 1 0 HD domain DUF2683 PF10884.8 EEQ27739.1 - 0.21 11.8 1.7 0.69 10.2 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) DUF445 PF04286.12 EEQ27739.1 - 1.5 8.5 6.4 0.23 11.2 1.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF445) FAM27 PF15832.5 EEQ27740.1 - 0.0074 16.8 2.9 0.01 16.4 2.9 1.3 1 0 0 1 1 1 1 FAM27 D and E protein family ArsA_ATPase PF02374.15 EEQ27742.1 - 1.6e-112 375.6 0.0 1.8e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EEQ27742.1 - 5.2e-14 52.5 0.1 1.9e-12 47.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EEQ27742.1 - 2e-12 47.3 0.0 3.6e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EEQ27742.1 - 7e-06 25.7 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EEQ27742.1 - 1.4e-05 24.7 0.8 0.00019 21.0 0.1 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EEQ27742.1 - 2e-05 24.3 0.2 0.00065 19.4 0.0 2.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EEQ27742.1 - 9e-05 22.1 0.0 0.00029 20.4 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 EEQ27742.1 - 0.057 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 EEQ27742.1 - 0.066 12.4 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EEQ27742.1 - 0.19 12.3 0.0 0.89 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EEQ27742.1 - 0.22 11.1 0.0 0.78 9.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ferric_reduct PF01794.19 EEQ27743.1 - 4.1e-22 78.6 16.7 4.7e-22 78.4 14.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EEQ27743.1 - 5e-15 56.0 0.0 9.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EEQ27743.1 - 2.3e-06 27.6 0.0 0.076 13.1 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain Phage_holin_2_1 PF04971.12 EEQ27743.1 - 0.015 15.3 0.9 0.039 14.0 0.9 1.7 1 0 0 1 1 1 0 Bacteriophage P21 holin S NAD_binding_1 PF00175.21 EEQ27743.1 - 0.039 14.6 0.0 8.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2219 PF09982.9 EEQ27743.1 - 0.071 12.4 0.1 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2219) Transthyretin PF00576.21 EEQ27744.1 - 5.6e-29 101.0 0.0 8.2e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 HIUase/Transthyretin family Aft1_HRA PF11786.8 EEQ27745.1 - 2.7e-22 78.9 9.9 2.7e-22 78.9 9.9 3.9 2 1 1 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.8 EEQ27745.1 - 9.2e-19 68.4 3.4 9.2e-19 68.4 3.4 4.4 3 2 1 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.8 EEQ27745.1 - 1.8e-17 63.5 7.7 4.5e-17 62.2 5.1 2.8 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 EEQ27745.1 - 6.8e-09 35.7 8.8 1.2e-08 35.0 8.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EEQ27745.1 - 0.0022 18.0 7.6 0.0039 17.2 7.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EEQ27745.1 - 0.055 14.0 3.6 0.1 13.1 3.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor PARP PF00644.20 EEQ27746.1 - 6e-11 42.3 0.1 1.2e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 EEQ27746.1 - 2.6e-07 30.4 0.0 5.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme COG7 PF10191.9 EEQ27747.1 - 0.079 11.2 0.0 0.24 9.6 0.0 1.7 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) RNA_pol_Rpb4 PF03874.16 EEQ27748.1 - 2e-06 28.2 3.1 0.024 15.0 0.1 2.8 2 1 0 2 2 2 2 RNA polymerase Rpb4 GST_N PF02798.20 EEQ27749.1 - 1.6e-19 70.0 0.0 3.8e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ27749.1 - 3.8e-16 59.3 0.0 8.4e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EEQ27749.1 - 1.8e-15 57.0 0.0 3.9e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEQ27749.1 - 6.2e-10 39.2 0.8 1.2e-09 38.3 0.3 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ27749.1 - 3.3e-06 27.0 1.2 6.2e-06 26.1 1.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ27749.1 - 1.2e-05 25.4 0.1 2.2e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Nop PF01798.18 EEQ27750.1 - 3.7e-68 229.4 1.7 3.7e-68 229.4 1.7 2.2 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EEQ27750.1 - 9.9e-22 77.1 1.3 9.9e-22 77.1 1.3 2.8 2 1 0 2 2 2 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.16 EEQ27751.1 - 3.5e-108 362.1 0.0 3.9e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.6 EEQ27752.1 - 1.9e-41 142.1 1.7 1.1e-35 123.3 0.8 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EEQ27752.1 - 8.4e-34 116.0 0.0 1.9e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EEQ27752.1 - 3.7e-14 52.5 0.3 7.5e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EEQ27752.1 - 0.0017 17.9 0.1 0.0028 17.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SbcCD_C PF13558.6 EEQ27753.1 - 0.089 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ubiquitin PF00240.23 EEQ27754.1 - 0.0026 17.5 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 EEQ27754.1 - 0.0028 18.3 0.0 0.0044 17.7 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PIG-H PF10181.9 EEQ27755.1 - 3.5e-26 90.9 1.3 5.8e-26 90.2 0.1 2.0 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.20 EEQ27756.1 - 3.8e-36 123.8 0.0 6.5e-35 119.9 0.0 2.8 3 0 0 3 3 3 1 tRNA pseudouridine synthase DUF3408 PF11888.8 EEQ27756.1 - 0.91 9.7 6.6 1.8 8.7 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Ndc1_Nup PF09531.10 EEQ27756.1 - 3.4 6.2 5.0 4.5 5.8 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Amidoligase_2 PF12224.8 EEQ27757.1 - 7.6e-06 25.8 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Ribosomal_S2 PF00318.20 EEQ27758.1 - 5.2e-26 91.2 0.1 3e-14 52.8 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EEQ27758.1 - 7.4e-06 27.2 16.9 1.4e-05 26.4 16.9 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 EEQ27759.1 - 1.5e-24 86.0 2.3 3.5e-24 84.8 0.3 2.3 2 0 0 2 2 2 1 Ribosomal protein S15 HisKA_3 PF07730.13 EEQ27760.1 - 0.57 10.8 7.1 1.6 9.3 7.1 1.8 1 0 0 1 1 1 0 Histidine kinase DEAD PF00270.29 EEQ27761.1 - 4.5e-35 121.0 0.0 7.4e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EEQ27761.1 - 2.1e-20 72.7 0.0 3.8e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EEQ27761.1 - 3.9e-20 72.2 0.0 1.4e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EEQ27761.1 - 0.015 15.6 0.1 0.083 13.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain Terminase_6 PF03237.15 EEQ27761.1 - 0.079 12.6 0.3 0.7 9.5 0.0 2.3 3 0 0 3 3 3 0 Terminase-like family SRP_SPB PF02978.19 EEQ27761.1 - 0.14 12.8 3.1 0.72 10.5 2.5 2.3 2 0 0 2 2 2 0 Signal peptide binding domain XPG_I PF00867.18 EEQ27763.1 - 5.7e-22 77.9 0.0 1.2e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 EEQ27763.1 - 7.8e-12 46.0 0.0 7.8e-12 46.0 0.0 2.4 3 0 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 EEQ27763.1 - 4e-06 27.2 0.0 9.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EEQ27763.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing Actin PF00022.19 EEQ27764.1 - 3.2e-21 75.4 0.0 1.5e-12 46.9 0.0 3.4 3 1 0 3 3 3 3 Actin MreB_Mbl PF06723.13 EEQ27764.1 - 0.087 11.6 0.0 0.23 10.2 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein Aldose_epim PF01263.20 EEQ27766.1 - 8.9e-51 173.0 0.3 1.1e-50 172.6 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.25 EEQ27768.1 - 6.8e-12 45.3 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27768.1 - 1.5e-08 34.2 0.0 2.3e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Carb_anhydrase PF00194.21 EEQ27770.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic-type carbonic anhydrase HECT PF00632.25 EEQ27770.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) APH PF01636.23 EEQ27771.1 - 1.9e-05 24.7 0.5 3.6e-05 23.8 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ27771.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase SecA_PP_bind PF01043.20 EEQ27771.1 - 0.2 12.4 0.0 0.4 11.3 0.0 1.5 1 0 0 1 1 1 0 SecA preprotein cross-linking domain Sec34 PF04136.15 EEQ27772.1 - 1.5e-50 171.0 0.4 1.5e-50 171.0 0.4 1.9 2 0 0 2 2 2 1 Sec34-like family SYCE1 PF15233.6 EEQ27772.1 - 0.15 12.1 1.3 0.56 10.2 0.9 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Neur_chan_memb PF02932.16 EEQ27773.1 - 0.013 15.5 1.3 0.025 14.7 0.0 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Mannitol_dh_C PF08125.13 EEQ27774.1 - 7.9e-40 136.9 0.0 1.8e-39 135.7 0.0 1.6 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EEQ27774.1 - 1.8e-19 70.4 0.4 4.9e-19 69.0 0.2 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain Sacchrp_dh_NADP PF03435.18 EEQ27774.1 - 0.025 14.9 0.2 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 EEQ27774.1 - 0.041 13.1 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EEQ27774.1 - 0.062 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EEQ27774.1 - 0.087 13.4 0.7 0.31 11.6 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 EEQ27774.1 - 0.11 11.6 0.5 0.7 9.0 0.1 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RCC1 PF00415.18 EEQ27775.1 - 2e-31 108.4 9.6 1.3e-07 32.1 0.1 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EEQ27775.1 - 9.7e-16 57.1 25.8 1e-05 25.1 0.2 6.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 EEQ27775.1 - 0.28 11.2 4.9 57 3.8 0.1 4.4 4 0 0 4 4 4 0 Galactose oxidase, central domain Rad9 PF04139.13 EEQ27776.1 - 2.2e-53 181.3 0.1 3.1e-53 180.8 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EEQ27776.1 - 2.5e-05 23.5 0.0 0.0002 20.5 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Vta1_C PF18097.1 EEQ27776.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Vta1 C-terminal domain Pkinase PF00069.25 EEQ27777.1 - 4e-63 213.2 0.0 5.7e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27777.1 - 2.2e-43 148.4 0.0 3.4e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ27777.1 - 3.2e-10 39.8 0.0 7.1e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EEQ27777.1 - 0.003 16.9 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEQ27777.1 - 0.0032 16.3 0.0 0.0074 15.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEQ27777.1 - 0.059 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family RepL PF05732.11 EEQ27777.1 - 0.06 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) EGF_Tenascin PF18720.1 EEQ27779.1 - 0.022 14.8 7.8 0.022 14.8 7.8 16.4 16 0 0 16 16 16 0 Tenascin EGF domain GCP_C_terminal PF04130.13 EEQ27780.1 - 1.6e-101 339.8 0.0 3.5e-101 338.8 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EEQ27780.1 - 1.5e-79 267.8 0.0 1.4e-78 264.6 0.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF2373 PF10180.9 EEQ27781.1 - 1.8e-19 69.4 0.0 3.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) BRF1 PF07741.13 EEQ27781.1 - 9.6 6.6 15.3 6.9 7.1 0.4 3.7 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Proteasome PF00227.26 EEQ27782.1 - 1.8e-49 167.8 0.0 2.5e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEQ27782.1 - 4.5e-13 48.6 0.3 8.8e-13 47.7 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.17 EEQ27782.1 - 0.0047 17.4 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family DDE_Tnp_IS1595 PF12762.7 EEQ27786.1 - 0.042 13.9 0.2 0.051 13.6 0.2 1.1 1 0 0 1 1 1 0 ISXO2-like transposase domain PTR2 PF00854.21 EEQ27787.1 - 2.2e-91 306.6 9.7 4.2e-91 305.7 9.7 1.4 1 1 0 1 1 1 1 POT family Glyco_hydro_18 PF00704.28 EEQ27788.1 - 2e-88 297.1 1.4 2.4e-88 296.9 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.23 EEQ27789.1 - 5.7e-34 115.7 0.7 9.7e-34 115.0 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EEQ27789.1 - 1.5e-26 92.3 1.9 1.5e-26 92.3 1.9 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EEQ27789.1 - 4.1e-16 58.6 0.8 7.4e-16 57.7 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEQ27789.1 - 2.5e-05 24.7 0.2 0.00013 22.4 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEQ27789.1 - 0.00085 19.4 0.6 0.0019 18.3 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EEQ27789.1 - 0.0061 16.5 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EEQ27789.1 - 0.0081 16.5 0.9 0.013 15.8 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 EEQ27789.1 - 0.0086 16.6 0.9 0.012 16.1 0.9 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.21 EEQ27789.1 - 0.013 15.7 0.3 0.021 15.0 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 EEQ27789.1 - 0.023 14.7 1.1 6.1 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain zf-H2C2_2 PF13465.6 EEQ27790.1 - 1.9e-09 37.5 5.6 0.00077 19.8 0.2 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EEQ27790.1 - 1.6e-06 28.3 18.2 0.0052 17.2 5.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ27790.1 - 1.4e-05 25.6 15.6 0.013 16.2 4.2 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EEQ27790.1 - 0.029 14.4 8.4 0.69 10.0 3.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EEQ27790.1 - 0.076 12.8 8.6 0.034 13.9 3.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain MAGUK_N_PEST PF10608.9 EEQ27790.1 - 0.85 10.1 4.2 4.1 7.9 0.0 2.9 3 1 0 3 3 3 0 Polyubiquitination (PEST) N-terminal domain of MAGUK zf-BED PF02892.15 EEQ27790.1 - 1.4 9.0 6.7 1.8 8.6 3.6 2.5 1 1 1 2 2 2 0 BED zinc finger zf-LYAR PF08790.11 EEQ27790.1 - 9.1 6.3 10.0 30 4.6 0.0 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DUF155 PF02582.14 EEQ27791.1 - 8.8e-51 172.5 0.0 1.3e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.20 EEQ27792.1 - 2e-18 66.6 0.1 6.1e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40_like PF17005.5 EEQ27792.1 - 0.0089 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain WD40 PF00400.32 EEQ27792.1 - 0.06 14.2 1.5 54 4.9 0.0 4.4 4 1 0 4 4 4 0 WD domain, G-beta repeat RPN7 PF10602.9 EEQ27792.1 - 0.14 11.9 0.0 0.52 10.0 0.0 1.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Vps39_1 PF10366.9 EEQ27792.1 - 0.17 12.1 0.0 0.57 10.5 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Pox_Ag35 PF03286.14 EEQ27792.1 - 0.25 11.1 7.1 0.53 10.0 7.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 EEQ27792.1 - 0.77 9.8 6.0 1.7 8.6 6.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 EEQ27792.1 - 1.6 8.4 12.0 3.2 7.4 12.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-RING_5 PF14634.6 EEQ27792.1 - 7.2 6.7 9.0 0.076 13.0 0.5 2.1 3 0 0 3 3 3 0 zinc-RING finger domain MTBP_C PF14920.6 EEQ27793.1 - 0.36 10.5 7.1 0.52 10.0 7.1 1.2 1 0 0 1 1 1 0 MDM2-binding Podoplanin PF05808.11 EEQ27793.1 - 0.99 9.5 15.2 0.63 10.1 13.2 1.6 2 0 0 2 2 2 0 Podoplanin SOG2 PF10428.9 EEQ27793.1 - 4 6.5 13.6 4.7 6.3 13.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PP_M1 PF03012.14 EEQ27793.1 - 7.3 6.0 7.4 0.81 9.2 0.2 2.0 2 0 0 2 2 2 0 Phosphoprotein CP2 PF04516.15 EEQ27794.1 - 7.9e-78 260.9 0.0 1.3e-77 260.2 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Metallopep PF12044.8 EEQ27795.1 - 7.7e-115 383.9 0.0 4.5e-58 196.9 0.0 2.1 2 0 0 2 2 2 2 Putative peptidase family FlgT_M PF16539.5 EEQ27795.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain GST_N_3 PF13417.6 EEQ27797.1 - 2.9e-09 37.2 0.1 5.2e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ27797.1 - 3.3e-08 33.4 0.1 8.3e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EEQ27797.1 - 1.2e-06 28.7 0.0 3.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEQ27797.1 - 0.00021 21.5 0.1 0.00045 20.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ27797.1 - 0.00022 21.4 0.0 0.00038 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EEQ27797.1 - 0.0035 17.7 0.0 0.0066 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EEQ27797.1 - 0.08 13.7 0.0 0.13 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DJ-1_PfpI PF01965.24 EEQ27798.1 - 9.7e-11 41.7 0.0 2.8e-10 40.2 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EEQ27798.1 - 0.043 13.5 0.2 0.17 11.6 0.2 1.9 1 1 0 1 1 1 0 ThiJ/PfpI family-like DNA_ligase_A_M PF01068.21 EEQ27799.1 - 1e-52 178.8 0.0 5.4e-50 169.9 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EEQ27799.1 - 3.8e-38 131.5 0.0 8.1e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EEQ27799.1 - 2.5e-18 66.5 0.0 7.4e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region NuDC PF16273.5 EEQ27799.1 - 0.016 15.7 0.3 0.04 14.4 0.3 1.6 1 0 0 1 1 1 0 Nuclear distribution C domain mRNA_cap_enzyme PF01331.19 EEQ27799.1 - 0.17 11.7 0.0 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain RINT1_TIP1 PF04437.13 EEQ27800.1 - 6.8e-182 605.8 0.1 1.4e-180 601.4 0.0 2.2 2 1 0 2 2 2 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 EEQ27800.1 - 0.046 14.2 1.0 0.14 12.6 1.0 1.9 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF883 PF05957.13 EEQ27800.1 - 0.22 12.2 3.5 0.99 10.1 1.7 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Tweety PF04906.13 EEQ27800.1 - 2.2 6.9 3.8 1.3 7.6 0.1 2.0 1 1 0 2 2 2 0 Tweety Pyridoxal_deC PF00282.19 EEQ27801.1 - 8.3e-76 255.1 0.0 2.2e-75 253.7 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain PUF PF00806.19 EEQ27801.1 - 2.2e-14 52.3 0.0 1.3 8.9 0.0 8.4 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat Aminotran_5 PF00266.19 EEQ27801.1 - 4.3e-06 25.9 0.0 6.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EEQ27801.1 - 0.00017 21.0 0.1 0.00041 19.7 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Glyoxalase_2 PF12681.7 EEQ27802.1 - 2e-07 30.9 0.1 3.4e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EEQ27802.1 - 3e-07 30.7 0.1 5e-07 30.0 0.1 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.25 EEQ27803.1 - 1.6e-31 109.3 0.0 2.7e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ27803.1 - 3.3e-24 85.7 0.0 5.6e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ27803.1 - 0.00023 21.1 0.3 0.00069 19.6 0.3 1.7 1 1 0 1 1 1 1 KR domain Sof1 PF04158.14 EEQ27804.1 - 1.3e-29 102.3 14.9 2.2e-29 101.5 14.9 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EEQ27804.1 - 2.5e-27 94.6 7.7 1.6e-05 25.6 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ27804.1 - 4.6e-08 33.2 0.0 0.17 12.2 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ27804.1 - 0.00058 18.9 0.0 0.054 12.5 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RPN6_N PF18055.1 EEQ27805.1 - 4e-45 152.9 1.8 6e-45 152.4 0.4 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EEQ27805.1 - 2.1e-19 70.0 1.0 3.9e-19 69.1 0.1 1.9 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EEQ27805.1 - 1.5e-11 43.8 0.5 4.1e-11 42.4 0.5 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 EEQ27805.1 - 2.6e-06 27.6 14.8 0.0025 18.0 1.2 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ27805.1 - 6.7e-06 25.7 5.2 1.4e-05 24.7 2.2 2.5 1 1 2 3 3 3 1 MalT-like TPR region DDRGK PF09756.9 EEQ27805.1 - 0.00039 20.1 1.6 0.00058 19.5 0.2 1.9 2 0 0 2 2 2 1 DDRGK domain TPR_1 PF00515.28 EEQ27805.1 - 0.001 18.8 1.9 4.9 7.1 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ27805.1 - 0.0016 18.4 2.2 5.8 7.2 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ27805.1 - 0.0023 17.9 5.7 54 4.3 0.3 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EEQ27805.1 - 0.039 14.6 3.2 1.9 9.4 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ27805.1 - 0.078 13.6 9.8 1.2 9.9 0.1 5.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ27805.1 - 0.087 13.7 10.1 1.5 9.9 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ27805.1 - 0.18 12.1 5.1 70 4.0 0.0 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat SWIB PF02201.18 EEQ27806.1 - 4.7e-23 80.8 0.0 9.2e-23 79.9 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain TRAM_LAG1_CLN8 PF03798.16 EEQ27807.1 - 6.8e-49 166.3 17.1 9.7e-49 165.8 17.1 1.2 1 0 0 1 1 1 1 TLC domain SO_alpha_A3 PF17806.1 EEQ27808.1 - 0.1 13.0 9.5 5.5 7.4 0.0 6.0 6 0 0 6 6 6 0 Sarcosine oxidase A3 domain Transposase_22 PF02994.14 EEQ27808.1 - 0.11 12.7 0.9 28 5.0 0.0 4.1 3 0 0 3 3 3 0 L1 transposable element RBD-like domain DUF948 PF06103.11 EEQ27808.1 - 0.11 12.7 0.0 0.11 12.7 0.0 11.4 10 4 2 13 13 13 0 Bacterial protein of unknown function (DUF948) DUF2229 PF09989.9 EEQ27808.1 - 0.13 11.9 0.0 0.13 11.9 0.0 4.9 6 1 0 6 6 6 0 CoA enzyme activase uncharacterised domain (DUF2229) SCO1-SenC PF02630.14 EEQ27808.1 - 1.9 8.4 9.4 3.4 7.6 0.1 4.5 5 0 0 5 5 5 0 SCO1/SenC HALZ PF02183.18 EEQ27808.1 - 2.7 8.3 12.7 3.1 8.1 1.5 5.2 6 0 0 6 6 6 0 Homeobox associated leucine zipper DUF1664 PF07889.12 EEQ27808.1 - 3.2 7.8 42.0 0.42 10.7 0.6 9.8 5 4 5 12 12 12 0 Protein of unknown function (DUF1664) Ribosomal_L27e PF01777.18 EEQ27809.1 - 1.8e-38 130.7 3.6 2.7e-38 130.2 3.6 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EEQ27809.1 - 0.00027 20.8 0.2 0.00096 19.0 0.2 1.9 2 0 0 2 2 2 1 KOW motif Band_7 PF01145.25 EEQ27811.1 - 1.4e-27 96.8 2.2 2.3e-27 96.1 2.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EEQ27811.1 - 0.042 13.5 0.1 0.067 12.9 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF3598 PF12204.8 EEQ27811.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) PHD PF00628.29 EEQ27812.1 - 6.8e-08 32.3 9.7 1.2e-07 31.4 9.7 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EEQ27812.1 - 0.19 11.6 7.2 0.38 10.7 7.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 EEQ27812.1 - 0.89 9.2 9.3 0.23 11.0 4.9 2.3 2 1 0 2 2 2 0 PHD-finger CoA_transf_3 PF02515.17 EEQ27813.1 - 5.5e-128 427.2 0.0 6.3e-128 427.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.17 EEQ27814.1 - 7.1e-45 150.9 1.2 1.2e-22 79.7 0.5 2.2 2 0 0 2 2 2 2 Lumazine binding domain YabP PF07873.11 EEQ27814.1 - 0.0032 17.2 0.2 0.67 9.8 0.1 2.5 2 0 0 2 2 2 2 YabP family Lumazine_bd_2 PF12893.7 EEQ27814.1 - 0.042 14.5 0.1 0.11 13.2 0.0 1.7 1 1 0 1 1 1 0 Putative lumazine-binding Brix PF04427.18 EEQ27815.1 - 1.1e-49 169.1 0.4 1.6e-49 168.6 0.4 1.2 1 0 0 1 1 1 1 Brix domain MRNIP PF15749.5 EEQ27815.1 - 0.29 11.9 8.0 1 10.1 8.0 1.9 1 0 0 1 1 1 0 MRN-interacting protein DEAD PF00270.29 EEQ27816.1 - 3e-47 160.6 0.0 4.4e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ27816.1 - 2.6e-30 105.0 0.0 2.3e-29 101.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ27816.1 - 3.2e-05 24.0 0.0 6.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PGM_PMM_I PF02878.16 EEQ27817.1 - 1e-16 60.9 0.4 1.2e-07 31.6 0.1 3.1 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EEQ27817.1 - 3.9e-11 43.0 1.0 9.8e-11 41.7 0.3 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EEQ27817.1 - 0.00053 20.2 0.6 0.0022 18.2 0.6 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EEQ27817.1 - 0.0016 19.0 0.2 0.008 16.8 0.1 2.4 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II CinA_KH PF18146.1 EEQ27817.1 - 0.13 12.5 0.5 0.34 11.1 0.5 1.7 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain Per1 PF04080.13 EEQ27818.1 - 1.1e-105 353.0 11.7 1.4e-105 352.6 11.7 1.1 1 0 0 1 1 1 1 Per1-like family Methyltransf_25 PF13649.6 EEQ27819.1 - 8.2e-12 45.7 0.0 2e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ27819.1 - 1e-10 41.6 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEQ27819.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EEQ27819.1 - 7.5e-08 32.9 0.0 2.1e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ27819.1 - 5.8e-07 29.5 0.0 1.7e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EEQ27819.1 - 3.8e-06 26.1 0.0 5.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EEQ27819.1 - 1.4e-05 24.5 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EEQ27819.1 - 4.1e-05 23.6 0.4 0.00012 22.1 0.1 1.8 1 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EEQ27819.1 - 0.00023 20.8 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EEQ27819.1 - 0.00028 21.6 0.0 0.0006 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EEQ27819.1 - 0.0054 16.9 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PRMT5 PF05185.16 EEQ27819.1 - 0.013 15.4 0.1 0.027 14.3 0.1 1.6 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 EEQ27819.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ27819.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 EEQ27819.1 - 0.026 14.2 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 EEQ27819.1 - 0.047 13.4 0.2 0.079 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EEQ27819.1 - 0.083 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase MaoC_dehydratas PF01575.19 EEQ27820.1 - 2.2e-26 91.9 0.0 3.6e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EEQ27820.1 - 1.3e-07 31.8 0.0 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase TauD PF02668.16 EEQ27821.1 - 2.8e-38 132.3 0.0 3.8e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EEQ27821.1 - 0.0044 17.6 0.0 0.0093 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EEQ27821.1 - 0.078 12.1 0.0 1.5 7.9 0.0 2.0 2 0 0 2 2 2 0 CsiD AAA PF00004.29 EEQ27822.1 - 1.6e-40 138.6 0.0 3.5e-40 137.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EEQ27822.1 - 9.9e-19 67.1 0.2 2e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EEQ27822.1 - 5.1e-09 35.8 0.0 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EEQ27822.1 - 9.3e-05 22.9 1.9 0.014 15.8 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EEQ27822.1 - 0.00019 21.4 1.8 0.00072 19.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEQ27822.1 - 0.0003 20.6 0.0 0.00072 19.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ27822.1 - 0.0008 19.7 1.6 0.084 13.1 0.0 3.0 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 EEQ27822.1 - 0.0021 17.6 0.2 0.073 12.5 0.1 2.5 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 EEQ27822.1 - 0.0027 16.9 1.7 0.051 12.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 EEQ27822.1 - 0.0048 17.0 3.9 0.006 16.7 0.0 3.0 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EEQ27822.1 - 0.0079 15.6 0.1 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EEQ27822.1 - 0.011 15.9 0.0 0.036 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EEQ27822.1 - 0.065 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 EEQ27822.1 - 0.53 10.0 0.0 0.53 10.0 0.0 3.2 2 1 0 3 3 2 0 AAA domain F-box-like PF12937.7 EEQ27823.1 - 0.015 15.1 2.1 0.081 12.8 2.1 2.3 1 1 0 1 1 1 0 F-box-like LRR_8 PF13855.6 EEQ27823.1 - 0.022 14.5 0.4 0.085 12.6 0.4 2.0 1 0 0 1 1 1 0 Leucine rich repeat Pkinase PF00069.25 EEQ27824.1 - 2.8e-68 230.2 0.0 4e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27824.1 - 1.4e-31 109.8 0.0 2.5e-31 108.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.24 EEQ27824.1 - 4e-12 46.7 1.0 2e-11 44.4 0.1 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EEQ27824.1 - 4.8e-10 39.2 0.0 2.1e-09 37.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEQ27824.1 - 0.0017 17.4 0.2 0.0017 17.4 0.2 2.5 3 1 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 EEQ27824.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family C2 PF00168.30 EEQ27824.1 - 0.045 14.0 0.0 0.25 11.7 0.0 2.2 1 1 1 2 2 2 0 C2 domain FTA2 PF13095.6 EEQ27824.1 - 0.05 13.2 0.5 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EEQ27824.1 - 0.15 11.6 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4707 PF15806.5 EEQ27824.1 - 0.44 9.4 5.8 0.71 8.8 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) CRC_subunit PF08624.10 EEQ27825.1 - 1.8e-52 177.3 0.0 2.7e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Cyclin PF08613.11 EEQ27826.1 - 6.5e-10 39.6 0.1 1.1e-09 38.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin Caps_synth_GfcC PF06251.11 EEQ27826.1 - 0.0047 16.6 3.3 0.0072 16.0 3.3 1.2 1 0 0 1 1 1 1 Capsule biosynthesis GfcC DUF4407 PF14362.6 EEQ27826.1 - 0.055 12.8 2.3 0.092 12.1 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 EEQ27826.1 - 0.29 9.9 0.6 0.36 9.5 0.6 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EEQ27826.1 - 0.39 10.4 1.7 0.65 9.7 1.7 1.3 1 0 0 1 1 1 0 Connexin Abhydrolase_6 PF12697.7 EEQ27828.1 - 1.1e-06 29.4 0.0 1.8e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ27828.1 - 2.4e-05 24.1 0.0 4.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ27828.1 - 4.7e-05 22.8 0.2 0.00019 20.8 0.2 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EEQ27828.1 - 0.008 15.7 0.1 5.4 6.4 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 EEQ27828.1 - 0.092 12.3 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family LIDHydrolase PF10230.9 EEQ27828.1 - 0.11 12.0 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Fungal_trans_2 PF11951.8 EEQ27829.1 - 2.6e-07 29.8 1.6 4.8e-07 28.9 1.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ27829.1 - 3.2e-07 30.4 6.8 7.7e-07 29.1 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.22 EEQ27830.1 - 3.9e-30 105.0 0.0 9.5e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 EEQ27830.1 - 0.002 17.6 0.1 0.0055 16.1 0.0 1.7 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) PBP1_TM PF14812.6 EEQ27830.1 - 0.3 11.5 14.5 0.46 10.9 1.5 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dor1 PF04124.12 EEQ27831.1 - 1.4e-46 158.8 5.5 1.9e-36 125.4 3.1 2.5 1 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 EEQ27831.1 - 0.0062 16.6 0.3 0.02 15.0 0.3 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec8_exocyst PF04048.14 EEQ27831.1 - 0.48 10.3 4.5 0.29 11.0 0.2 2.7 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain EST1 PF10374.9 EEQ27831.1 - 0.86 10.2 4.2 0.32 11.6 0.3 2.2 2 1 0 2 2 2 0 Telomerase activating protein Est1 EAF PF09816.9 EEQ27832.1 - 5.7e-17 62.0 0.1 1.2e-16 60.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.23 EEQ27833.1 - 4.7e-14 52.2 0.1 9e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEQ27833.1 - 0.0026 17.9 0.0 0.038 14.1 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 EEQ27833.1 - 0.0079 16.2 3.0 0.063 13.3 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat PRP38_assoc PF12871.7 EEQ27833.1 - 0.6 10.7 27.3 0.12 13.0 9.9 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PK PF00224.21 EEQ27834.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Methyltransf_23 PF13489.6 EEQ27835.1 - 7.2e-32 110.5 0.0 9.3e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ27835.1 - 6.6e-05 23.5 0.0 0.00048 20.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ27835.1 - 0.0015 19.2 0.0 0.003 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27835.1 - 0.015 16.0 0.0 0.089 13.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain DAO PF01266.24 EEQ27836.1 - 1e-45 156.8 0.5 1.2e-45 156.6 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ27836.1 - 3.1e-09 36.5 0.0 0.00046 19.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ27836.1 - 9e-06 25.8 0.1 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 EEQ27836.1 - 1.3e-05 24.4 0.1 0.00017 20.8 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EEQ27836.1 - 2.6e-05 23.5 1.6 0.1 11.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EEQ27836.1 - 8.3e-05 22.7 0.0 0.00047 20.3 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EEQ27836.1 - 0.0016 17.4 0.2 0.27 10.0 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 EEQ27836.1 - 0.036 13.1 0.0 0.84 8.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 EEQ27836.1 - 0.082 12.3 0.0 1.6 8.1 0.0 2.4 3 0 0 3 3 3 0 GMC oxidoreductase Pyr_redox PF00070.27 EEQ27836.1 - 0.16 12.6 0.0 0.45 11.1 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TBP PF00352.21 EEQ27837.1 - 2.1e-67 223.1 0.1 1e-32 111.9 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EEQ27837.1 - 5.5e-05 23.2 0.0 0.24 11.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EEQ27837.1 - 0.14 12.0 0.1 0.72 9.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Hamartin PF04388.12 EEQ27837.1 - 0.62 8.7 2.2 0.81 8.3 2.2 1.1 1 0 0 1 1 1 0 Hamartin protein ETF_QO PF05187.13 EEQ27838.1 - 4e-24 84.8 0.0 6.1e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 EEQ27838.1 - 0.0028 17.8 0.0 0.0088 16.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ27838.1 - 0.024 14.2 3.4 0.33 10.5 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EEQ27838.1 - 0.098 13.2 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.22 EEQ27839.1 - 3.4e-15 55.6 0.9 1.2e-07 31.4 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FolB PF02152.18 EEQ27840.1 - 1.4e-25 90.0 0.6 1.7e-20 73.7 0.2 2.6 3 0 0 3 3 3 2 Dihydroneopterin aldolase Pkinase PF00069.25 EEQ27841.1 - 4.9e-65 219.5 0.0 6.1e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27841.1 - 2.3e-29 102.5 0.0 3.2e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ27841.1 - 0.039 12.9 0.2 0.062 12.2 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EEQ27841.1 - 0.081 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EEQ27841.1 - 0.18 11.7 1.0 3.1 7.6 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family UreD PF01774.17 EEQ27842.1 - 0.043 13.7 0.2 0.078 12.9 0.2 1.4 1 0 0 1 1 1 0 UreD urease accessory protein RdDM_RDM1 PF09187.10 EEQ27842.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 Ndc80_HEC PF03801.13 EEQ27843.1 - 8e-60 200.9 0.3 1.6e-59 199.9 0.3 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.11 EEQ27843.1 - 0.085 11.7 41.1 0.084 11.7 10.3 3.5 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 EEQ27843.1 - 0.18 9.3 35.5 0.031 11.8 17.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 EEQ27843.1 - 0.6 10.6 14.6 26 5.3 2.4 4.6 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 EEQ27843.1 - 0.89 9.0 44.2 0.46 9.9 13.8 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 DUF812 PF05667.11 EEQ27843.1 - 1 8.2 34.5 0.18 10.7 15.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) CEP63 PF17045.5 EEQ27843.1 - 1.4 8.7 36.1 0.36 10.7 11.9 3.0 2 1 1 3 3 3 0 Centrosomal protein of 63 kDa TPR_MLP1_2 PF07926.12 EEQ27843.1 - 4.3 7.4 47.7 0.42 10.7 7.3 4.0 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 EEQ27843.1 - 4.4 6.6 50.8 0.54 9.6 23.7 3.7 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_CLD PF14073.6 EEQ27843.1 - 5.8 6.9 38.0 0.64 10.0 16.2 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of Cep57 Pex14_N PF04695.13 EEQ27844.1 - 1.2e-41 143.0 0.1 1.2e-41 143.0 0.1 2.9 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.8 EEQ27844.1 - 0.0067 14.0 2.9 0.0098 13.5 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 EEQ27844.1 - 0.016 14.7 1.6 0.027 13.9 1.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1043 PF06295.12 EEQ27844.1 - 0.14 12.1 1.6 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) MID_MedPIWI PF18296.1 EEQ27844.1 - 0.79 9.5 5.4 0.6 9.9 2.1 2.1 2 0 0 2 2 2 0 MID domain of medPIWI zf-C4H2 PF10146.9 EEQ27844.1 - 1.2 9.4 5.8 0.16 12.2 0.9 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein Senescence_reg PF04520.13 EEQ27844.1 - 6.8 7.5 13.4 3.6 8.4 8.2 2.4 2 1 0 2 2 2 0 Senescence regulator DUF4786 PF16027.5 EEQ27844.1 - 9.6 6.7 8.5 1.9 9.1 4.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4786) ABC_tran PF00005.27 EEQ27846.1 - 2.9e-33 115.3 0.0 6.6e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EEQ27846.1 - 1.7e-21 77.1 0.3 1.7e-21 77.1 0.3 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EEQ27846.1 - 8.8e-05 22.0 0.3 0.0076 15.7 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEQ27846.1 - 0.0012 19.4 1.3 0.013 16.0 0.3 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EEQ27846.1 - 0.014 15.1 0.3 0.04 13.6 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EEQ27846.1 - 0.025 13.9 0.1 0.059 12.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin EMP70 PF02990.16 EEQ27846.1 - 0.04 12.6 0.0 0.074 11.7 0.0 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 AAA_10 PF12846.7 EEQ27846.1 - 0.077 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain RsgA_GTPase PF03193.16 EEQ27846.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EEQ27846.1 - 0.12 12.6 0.4 0.48 10.7 0.4 2.0 1 1 0 1 1 1 0 AAA domain TTL PF03133.15 EEQ27848.1 - 2.5e-53 181.1 0.0 3.6e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EEQ27848.1 - 8.1e-50 169.3 0.0 1.1e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EEQ27848.1 - 0.0028 17.0 0.0 0.01 15.1 0.0 1.8 2 0 0 2 2 2 1 YheC/D like ATP-grasp Seipin PF06775.14 EEQ27849.1 - 1.7e-54 185.0 0.1 2.2e-54 184.6 0.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Aph-1 PF06105.12 EEQ27849.1 - 0.077 12.4 6.4 0.15 11.4 6.4 1.4 1 0 0 1 1 1 0 Aph-1 protein Not1 PF04054.15 EEQ27850.1 - 5.3e-141 469.8 0.4 5.3e-141 469.8 0.4 2.8 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EEQ27850.1 - 4.5e-93 310.8 3.5 1.4e-92 309.2 3.5 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EEQ27850.1 - 4.8e-51 172.5 2.0 1e-50 171.5 2.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EEQ27850.1 - 2.8e-40 137.5 0.0 1e-39 135.7 0.0 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EEQ27850.1 - 1e-28 100.3 0.5 2.9e-28 98.9 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat SH3_1 PF00018.28 EEQ27851.1 - 1.7e-12 46.8 0.2 3.5e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEQ27851.1 - 3.1e-10 39.7 0.0 5.7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ27851.1 - 3.6e-10 39.4 0.0 8.1e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DASH_Duo1 PF08651.10 EEQ27853.1 - 3.6e-31 106.8 0.1 5.5e-31 106.2 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 PEARLI-4 PF05278.12 EEQ27853.1 - 0.0042 16.7 4.2 0.0084 15.7 4.2 1.4 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) DUF745 PF05335.13 EEQ27853.1 - 0.038 13.7 12.5 0.065 12.9 12.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1509 PF07420.11 EEQ27853.1 - 4.1 6.3 8.5 5.5 5.9 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF4140 PF13600.6 EEQ27853.1 - 5.3 7.5 13.4 17 6.0 7.9 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4834 PF16118.5 EEQ27853.1 - 7.3 7.6 6.8 30 5.6 6.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) U79_P34 PF03064.16 EEQ27853.1 - 9.5 5.5 15.8 5.9 6.2 13.8 1.5 1 1 0 1 1 1 0 HSV U79 / HCMV P34 zf-primase PF09329.11 EEQ27855.1 - 3.9e-20 71.4 0.7 6.9e-20 70.6 0.7 1.4 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.10 EEQ27856.1 - 6.4e-40 137.0 1.8 2.6e-39 135.0 0.0 2.6 2 2 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EEQ27856.1 - 7.2e-25 87.0 1.0 1.7e-24 85.8 0.1 2.1 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain U1snRNP70_N PF12220.8 EEQ27856.1 - 0.029 15.0 1.2 0.029 15.0 1.2 2.6 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HAUS-augmin3 PF14932.6 EEQ27856.1 - 0.089 12.4 3.6 0.16 11.6 3.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Mog1 PF04603.12 EEQ27856.1 - 0.47 10.8 4.0 0.13 12.6 0.5 1.8 2 0 0 2 2 2 0 Ran-interacting Mog1 protein GalKase_gal_bdg PF10509.9 EEQ27857.1 - 2.9e-19 68.3 0.0 6e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EEQ27857.1 - 2.9e-15 56.4 0.0 8.7e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EEQ27857.1 - 9.5e-14 51.4 1.8 2.1e-13 50.3 1.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain TPP_enzyme_N PF02776.18 EEQ27858.1 - 3.3e-55 186.4 0.0 3.9e-54 182.9 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EEQ27858.1 - 1.7e-48 164.3 0.5 4.5e-46 156.4 0.0 3.1 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEQ27858.1 - 1.1e-40 138.5 0.2 2.6e-40 137.3 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EEQ27858.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PhnA_Zn_Ribbon PF08274.12 EEQ27859.1 - 0.0046 16.9 0.1 0.014 15.3 0.1 1.8 1 0 0 1 1 1 1 PhnA Zinc-Ribbon RINGv PF12906.7 EEQ27859.1 - 0.039 14.1 1.5 0.096 12.8 1.5 1.7 1 0 0 1 1 1 0 RING-variant domain MRP-L28 PF09812.9 EEQ27860.1 - 1.1e-05 25.6 0.0 1.4e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.22 EEQ27861.1 - 2.9e-47 160.3 0.0 3.3e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ27861.1 - 1.6e-20 73.5 0.0 2.4e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ27861.1 - 2.8e-06 26.9 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EEQ27861.1 - 0.0039 16.6 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EEQ27861.1 - 0.058 13.5 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EEQ27861.1 - 0.063 13.0 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EEQ27861.1 - 0.076 12.4 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ADH_zinc_N PF00107.26 EEQ27861.1 - 0.11 12.4 0.0 15 5.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase AAA_21 PF13304.6 EEQ27861.1 - 0.25 11.1 0.1 0.59 9.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NST1 PF13945.6 EEQ27862.1 - 1.6e-77 260.0 5.2 1.6e-77 260.0 5.2 4.7 2 2 3 5 5 5 1 Salt tolerance down-regulator Vps35 PF03635.17 EEQ27863.1 - 1.8e-80 271.5 0.2 2e-80 271.3 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 EF-hand_2 PF09068.11 EEQ27863.1 - 0.15 12.3 0.0 0.36 11.0 0.0 1.6 2 0 0 2 2 2 0 EF hand Vps35 PF03635.17 EEQ27864.1 - 5.6e-170 567.3 4.9 6.7e-170 567.1 4.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF4129 PF13559.6 EEQ27864.1 - 0.3 11.4 2.4 1.7 9.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) Ge1_WD40 PF16529.5 EEQ27866.1 - 0.0065 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF640 PF04852.12 EEQ27866.1 - 0.14 12.3 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF640) DUF1749 PF08538.10 EEQ27867.1 - 6.3e-94 314.4 0.0 7e-94 314.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 EEQ27867.1 - 0.00021 20.7 0.0 0.00061 19.1 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EEQ27867.1 - 0.00053 19.9 0.0 0.026 14.4 0.0 2.8 3 0 0 3 3 3 1 Serine hydrolase Abhydrolase_6 PF12697.7 EEQ27867.1 - 0.0019 18.9 0.0 0.0036 17.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EEQ27867.1 - 0.035 14.0 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 EEQ27867.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glycos_transf_2 PF00535.26 EEQ27868.1 - 9.8e-35 119.9 0.0 1.2e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EEQ27868.1 - 1.6e-15 57.6 0.0 2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EEQ27868.1 - 3.2e-07 30.1 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EEQ27868.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 UPA_2 PF17809.1 EEQ27868.1 - 0.066 13.0 0.0 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 UPA domain TPR_19 PF14559.6 EEQ27869.1 - 9.1e-08 32.5 0.0 0.0089 16.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ27869.1 - 0.00032 21.2 0.0 1.5 9.6 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ27869.1 - 0.014 15.7 0.1 1 9.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4332 PF14229.6 EEQ27869.1 - 0.048 13.9 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) TPR_2 PF07719.17 EEQ27869.1 - 0.06 13.5 0.2 42 4.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EEQ27869.1 - 0.078 13.6 0.5 14 6.7 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 EEQ27870.1 - 0.0095 15.9 0.0 0.02 14.9 0.0 1.5 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family HlyIII PF03006.20 EEQ27871.1 - 2.6e-60 203.9 11.5 3.2e-60 203.7 11.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related 60KD_IMP PF02096.20 EEQ27871.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.5 1 1 0 1 1 1 0 60Kd inner membrane protein adh_short_C2 PF13561.6 EEQ27872.1 - 4.1e-47 160.7 4.2 1.4e-43 149.1 4.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ27872.1 - 9.5e-46 155.7 2.8 1.2e-45 155.4 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ27872.1 - 2.7e-15 56.7 0.6 3.8e-15 56.3 0.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EEQ27872.1 - 0.0051 16.7 0.5 0.0078 16.1 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EEQ27872.1 - 0.048 13.7 0.7 0.11 12.6 0.6 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GDP_Man_Dehyd PF16363.5 EEQ27872.1 - 0.052 12.9 0.0 0.076 12.4 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltrans_RNA PF04452.14 EEQ27872.1 - 0.058 12.7 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase Polysacc_synt_2 PF02719.15 EEQ27872.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DDE_Tnp_1 PF01609.21 EEQ27872.1 - 0.079 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain ADH_zinc_N PF00107.26 EEQ27872.1 - 0.17 11.8 2.3 1.6 8.7 1.3 2.6 2 1 0 2 2 2 0 Zinc-binding dehydrogenase 3HCDH_RFF PF18321.1 EEQ27872.1 - 0.31 11.5 2.0 1 9.8 2.0 1.9 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Pkinase PF00069.25 EEQ27874.1 - 5.2e-55 186.7 0.0 6.7e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27874.1 - 9.9e-34 116.8 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ27874.1 - 0.00053 19.4 0.0 0.0011 18.4 0.0 1.5 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EEQ27874.1 - 0.0038 17.2 0.0 0.014 15.3 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EEQ27874.1 - 0.0082 15.1 0.3 0.014 14.4 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EEQ27874.1 - 0.025 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cadherin_C_2 PF16492.5 EEQ27876.1 - 0.11 13.2 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Pkinase PF00069.25 EEQ27877.1 - 3.7e-53 180.6 0.0 5.9e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27877.1 - 6.8e-23 81.3 0.0 3.9e-22 78.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EEQ27877.1 - 0.014 14.4 0.2 0.021 13.8 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 EEQ27877.1 - 0.028 13.2 0.1 0.028 13.2 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 EEQ27877.1 - 0.063 12.6 0.0 14 4.9 0.0 2.6 2 1 0 2 2 2 0 Kinase-like TMA7 PF09072.10 EEQ27878.1 - 7.8e-25 87.5 21.9 8.7e-25 87.3 21.9 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Filament PF00038.21 EEQ27879.1 - 0.043 13.4 0.3 0.065 12.8 0.3 1.2 1 0 0 1 1 1 0 Intermediate filament protein Fib_alpha PF08702.10 EEQ27879.1 - 0.074 13.2 2.2 0.2 11.9 2.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1690 PF07956.11 EEQ27879.1 - 0.33 11.4 1.6 0.64 10.4 1.6 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Baculo_PEP_C PF04513.12 EEQ27879.1 - 0.42 10.6 2.1 1.7 8.7 2.5 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Carbam_trans_N PF02543.15 EEQ27880.1 - 0.054 13.1 0.2 0.097 12.3 0.2 1.3 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus DUF1948 PF09185.10 EEQ27882.1 - 0.063 13.2 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Cyt-b5 PF00173.28 EEQ27885.1 - 4.7e-15 55.5 0.0 6.1e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RAMP4 PF06624.12 EEQ27885.1 - 0.078 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Ish1 PF10281.9 EEQ27886.1 - 2e-82 271.1 13.5 5.7e-14 52.1 0.0 7.6 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EEQ27886.1 - 1.8e-08 33.9 0.0 0.5 10.2 0.0 4.8 4 1 0 4 4 4 3 SAP domain HeH PF12949.7 EEQ27886.1 - 1.6e-06 27.7 0.2 1.3 8.8 0.0 4.9 5 0 0 5 5 5 3 HeH/LEM domain ANAPC2 PF08672.11 EEQ27886.1 - 0.0015 19.0 0.0 61 4.2 0.0 5.0 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.10 EEQ27886.1 - 0.0069 16.3 0.1 23 5.0 0.0 4.6 5 0 0 5 5 5 0 Slx4 endonuclease Recombinase PF07508.13 EEQ27886.1 - 0.021 15.2 1.8 4.6 7.7 0.0 3.8 4 1 0 4 4 4 0 Recombinase LEM PF03020.15 EEQ27886.1 - 0.026 14.1 0.0 15 5.3 0.0 3.2 4 0 0 4 4 4 0 LEM domain DUF2795 PF11387.8 EEQ27886.1 - 0.081 13.1 0.4 56 4.1 0.0 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) GFO_IDH_MocA PF01408.22 EEQ27886.1 - 0.11 13.3 0.0 0.34 11.7 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold YtxH PF12732.7 EEQ27886.1 - 0.64 10.6 3.7 2.1 9.0 0.2 3.2 3 0 0 3 3 3 0 YtxH-like protein PQ-loop PF04193.14 EEQ27887.1 - 2.3e-18 65.7 25.1 4.9e-12 45.4 3.0 3.5 4 0 0 4 4 4 2 PQ loop repeat LtrA PF06772.11 EEQ27887.1 - 0.0047 16.2 6.4 0.01 15.1 3.8 2.1 1 1 1 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) TrbC PF04956.13 EEQ27887.1 - 0.026 14.7 3.4 0.047 13.9 2.3 2.0 1 1 0 1 1 1 0 TrbC/VIRB2 family Arteri_GP4 PF02497.15 EEQ27887.1 - 0.036 14.2 0.1 0.076 13.1 0.1 1.5 1 1 0 1 1 1 0 Arterivirus glycoprotein OppC_N PF12911.7 EEQ27887.1 - 3 7.9 6.6 2.1 8.4 0.0 3.6 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C DUF4231 PF14015.6 EEQ27887.1 - 9.2 6.8 6.2 5.9 7.4 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF3813 PF12758.7 EEQ27888.1 - 0.091 13.1 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Pox_Ag35 PF03286.14 EEQ27888.1 - 2.7 7.8 7.6 3.3 7.4 7.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.12 EEQ27888.1 - 8.9 6.0 11.0 10 5.8 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2951 PF11166.8 EEQ27889.1 - 0.04 14.1 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Gly-zipper_Omp PF13488.6 EEQ27889.1 - 0.042 13.8 3.3 0.073 13.1 3.3 1.3 1 0 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.9 EEQ27889.1 - 3.7 7.7 6.2 8.3 6.6 6.2 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide FAD_binding_4 PF01565.23 EEQ27891.1 - 3.9e-23 81.7 1.8 6.2e-23 81.1 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EEQ27891.1 - 7.8e-07 29.1 0.1 1.4e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Aim21 PF11489.8 EEQ27892.1 - 2e-154 516.3 67.8 2e-154 516.3 67.8 2.3 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 EEQ27893.1 - 1.4e-29 102.7 13.5 9.4e-28 96.8 13.5 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P CbiN PF02553.15 EEQ27893.1 - 0.4 10.7 2.9 0.27 11.2 0.5 1.9 2 0 0 2 2 2 0 Cobalt transport protein component CbiN TMEM43 PF07787.12 EEQ27893.1 - 0.82 9.0 6.6 1.3 8.3 6.6 1.5 1 1 0 1 1 1 0 Transmembrane protein 43 NTF2 PF02136.20 EEQ27894.1 - 1.5e-31 109.5 0.1 1.7e-31 109.3 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 EEQ27894.1 - 0.054 12.7 0.2 0.12 11.5 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Mtr2 PF10429.9 EEQ27894.1 - 0.067 13.1 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Surp PF01805.20 EEQ27895.1 - 5.9e-09 35.8 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Surp module DUF1765 PF08578.10 EEQ27896.1 - 2.6e-41 141.0 0.1 5.1e-41 140.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.9 EEQ27898.1 - 3.2e-24 84.7 2.2 4.4e-24 84.2 2.2 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 EEQ27898.1 - 0.16 12.4 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.19 EEQ27899.1 - 7e-38 128.5 0.0 1.6e-19 69.7 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EEQ27899.1 - 1.3e-10 40.6 0.9 1.3e-10 40.6 0.9 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.20 EEQ27899.1 - 0.00031 20.8 0.0 0.00055 20.0 0.0 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 EEQ27899.1 - 0.029 14.5 0.0 2.8 8.0 0.0 2.5 2 1 0 3 3 3 0 Cyclin, C-terminal domain Cyclin_N PF00134.23 EEQ27899.1 - 0.16 11.7 0.1 1.7 8.4 0.1 2.1 2 0 0 2 2 2 0 Cyclin, N-terminal domain DZR PF12773.7 EEQ27899.1 - 0.21 11.6 1.9 0.74 9.9 0.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon DUF1610 PF07754.11 EEQ27899.1 - 1.2 9.2 4.4 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) TFR_dimer PF04253.15 EEQ27900.1 - 1.8e-31 108.8 0.1 3.7e-31 107.7 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EEQ27900.1 - 8.8e-15 54.9 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EEQ27900.1 - 1.4e-14 53.9 0.1 3.1e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 PA domain APH PF01636.23 EEQ27903.1 - 7.4e-08 32.6 0.9 0.0022 18.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEQ27903.1 - 3.6e-06 26.5 2.1 2.2e-05 23.9 0.6 2.1 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEQ27903.1 - 2.4e-05 24.0 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.11 EEQ27903.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Cadherin-like PF12733.7 EEQ27903.1 - 0.02 15.4 0.0 2 9.0 0.0 2.3 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain Choline_kinase PF01633.20 EEQ27903.1 - 0.023 14.3 0.1 1.8 8.1 0.1 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ27903.1 - 0.043 13.2 0.2 0.069 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein kinase domain HMG_CoA_synt_C PF08540.10 EEQ27904.1 - 4e-104 348.2 0.1 5e-104 347.8 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EEQ27904.1 - 1.4e-95 318.1 0.2 2.1e-95 317.5 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal GFO_IDH_MocA PF01408.22 EEQ27906.1 - 1e-10 42.5 0.0 1.9e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EEQ27906.1 - 0.0056 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.16 EEQ27907.1 - 8.6e-34 116.2 0.1 1.2e-33 115.7 0.1 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EEQ27907.1 - 5.8e-25 87.7 0.0 1.1e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EEQ27907.1 - 2.8e-16 60.0 0.0 6.5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EEQ27907.1 - 5.7e-09 36.0 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.24 EEQ27908.1 - 6.4e-26 91.9 0.0 7.2e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Minor_capsid_2 PF11114.8 EEQ27908.1 - 0.064 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein Sugar_tr PF00083.24 EEQ27911.1 - 2.5e-90 303.5 21.2 2.5e-90 303.5 21.2 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ27911.1 - 5.2e-12 45.4 43.3 3.4e-06 26.2 23.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Piwi PF02171.17 EEQ27912.1 - 7.6e-70 235.5 0.0 1.9e-69 234.2 0.0 1.6 2 0 0 2 2 2 1 Piwi domain ArgoN PF16486.5 EEQ27912.1 - 5.2e-19 69.2 0.4 1.4e-18 67.9 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EEQ27912.1 - 2.6e-14 52.6 2.4 2e-13 49.8 0.2 2.5 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 EEQ27912.1 - 2.6e-13 50.0 0.6 4.7e-13 49.1 0.6 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EEQ27912.1 - 1.2e-10 41.5 0.0 3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EEQ27912.1 - 3.5e-09 36.9 0.1 9.3e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain DUF3611 PF12263.8 EEQ27914.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Peptidase_C28 PF05408.11 EEQ27914.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase Y_phosphatase PF00102.27 EEQ27915.1 - 6.8e-54 182.9 0.0 1.3e-53 182.0 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EEQ27915.1 - 0.0012 19.0 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EEQ27915.1 - 0.011 15.6 0.2 0.032 14.0 0.2 1.8 1 1 1 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EEQ27915.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CDC45 PF02724.14 EEQ27915.1 - 0.071 11.4 8.7 0.092 11.0 8.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EEQ27915.1 - 1.1 9.0 22.7 1.9 8.2 22.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EEQ27915.1 - 1.2 7.2 21.1 1.5 6.9 21.1 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 EEQ27915.1 - 1.4 7.6 6.1 0.67 8.7 4.0 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein RNA_pol_3_Rpc31 PF11705.8 EEQ27915.1 - 1.8 8.8 25.8 3 8.0 25.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 EEQ27915.1 - 1.9 8.4 18.7 2.9 7.8 18.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 EEQ27915.1 - 6.3 6.3 18.9 9.4 5.7 18.9 1.3 1 0 0 1 1 1 0 PPP4R2 VanZ PF04892.12 EEQ27916.1 - 1.4e-05 25.8 0.5 2e-05 25.2 0.5 1.2 1 0 0 1 1 1 1 VanZ like family Bromodomain PF00439.25 EEQ27917.1 - 2.1e-18 66.2 0.2 5.5e-18 64.8 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EEQ27917.1 - 2e-08 34.1 0.0 5.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated NADH_Oxid_Nqo15 PF11497.8 EEQ27917.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 Bromo_TP_like PF17027.5 EEQ27917.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Histone-fold protein DUF3947 PF13135.6 EEQ27917.1 - 1.6 9.0 5.9 3.6 7.9 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) TPP_enzyme_N PF02776.18 EEQ27918.1 - 1.3e-31 109.5 0.0 2.1e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEQ27918.1 - 6.7e-21 74.5 0.0 3.1e-20 72.3 0.0 2.0 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EEQ27918.1 - 1.4e-14 54.2 0.0 3.4e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EEQ27918.1 - 0.015 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component THUMP PF02926.17 EEQ27919.1 - 1.2e-08 35.2 0.0 1.9e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 THUMP domain Lgl_C PF08596.10 EEQ27920.1 - 3.6e-91 305.8 0.0 8.9e-57 192.6 0.0 2.6 1 1 1 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EEQ27920.1 - 0.1 13.5 3.2 16 6.5 0.1 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat bZIP_1 PF00170.21 EEQ27923.1 - 9e-07 28.9 6.4 1.7e-06 28.0 6.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EEQ27923.1 - 0.0044 17.1 6.5 0.011 15.8 6.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Stm1_N PF09598.10 EEQ27924.1 - 4.5e-13 49.8 11.9 4.5e-13 49.8 11.9 4.2 2 2 1 3 3 3 1 Stm1 HABP4_PAI-RBP1 PF04774.15 EEQ27924.1 - 0.00022 22.1 13.8 0.00022 22.1 13.8 2.6 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family PRIMA1 PF16101.5 EEQ27925.1 - 5.3 7.1 17.3 0.16 12.0 4.1 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF1793 PF08760.11 EEQ27926.1 - 3.9e-71 238.9 0.0 6.4e-71 238.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 EEQ27926.1 - 1.4e-61 207.2 0.7 1e-48 165.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EEQ27926.1 - 3.4e-30 105.5 2.8 1.3e-28 100.3 0.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 EEQ27926.1 - 0.015 14.8 0.1 0.038 13.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Pab87_oct PF13969.6 EEQ27926.1 - 0.028 14.5 0.0 0.074 13.1 0.0 1.7 1 0 0 1 1 1 0 Pab87 octamerisation domain tRNA-synt_1c PF00749.21 EEQ27927.1 - 8.2e-101 337.0 0.0 1.1e-100 336.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EEQ27927.1 - 5.9e-40 137.0 0.2 9.6e-40 136.3 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 EEQ27927.1 - 0.0003 20.9 0.1 0.014 15.5 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EEQ27927.1 - 0.00051 20.2 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ27927.1 - 0.0078 16.2 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DEAD PF00270.29 EEQ27931.1 - 2.1e-40 138.4 0.0 4.9e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ27931.1 - 6.3e-30 103.8 0.0 1.3e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ27931.1 - 5.4e-05 23.3 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EEQ27931.1 - 0.0034 16.2 0.0 0.0064 15.3 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 EEQ27931.1 - 0.14 12.4 0.1 1.5 9.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain HCO3_cotransp PF00955.21 EEQ27932.1 - 5.4e-75 253.1 19.5 1.1e-40 140.0 2.0 3.0 2 1 1 3 3 3 3 HCO3- transporter family SF1-HH PF16275.5 EEQ27933.1 - 5.4e-43 145.9 1.0 1.1e-42 144.9 1.0 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EEQ27933.1 - 1.3e-11 44.0 11.1 2e-05 24.5 3.6 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EEQ27933.1 - 2.7e-08 33.5 0.1 5.1e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EEQ27933.1 - 2.2e-06 27.5 6.4 0.0013 18.6 2.8 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EEQ27933.1 - 0.0005 19.7 4.7 0.27 11.0 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EEQ27933.1 - 0.0028 17.5 8.3 0.54 10.1 1.5 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EEQ27933.1 - 0.021 14.6 0.6 0.021 14.6 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle GST_N_3 PF13417.6 EEQ27934.1 - 9.8e-15 54.7 0.0 1.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EEQ27934.1 - 3.9e-14 52.7 0.0 7.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEQ27934.1 - 5.4e-11 42.6 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EEQ27934.1 - 8.5e-11 42.0 0.0 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EEQ27934.1 - 1.7e-10 41.0 0.0 3.3e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ27934.1 - 2.8e-07 30.4 0.0 6.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ferric_reduct PF01794.19 EEQ27935.1 - 3e-23 82.3 14.3 8.4e-23 80.9 11.7 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EEQ27935.1 - 9.2e-18 64.8 0.0 2.7e-15 56.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EEQ27935.1 - 4.5e-13 49.2 0.0 3.7e-11 43.1 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain CLU PF13236.6 EEQ27938.1 - 4.1e-74 249.1 0.0 7.3e-74 248.3 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EEQ27938.1 - 2.6e-53 180.7 0.0 7.1e-53 179.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EEQ27938.1 - 5e-27 94.0 4.0 1.5e-12 47.6 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 EEQ27938.1 - 7.9e-25 87.0 0.3 3.6e-24 84.9 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 EEQ27938.1 - 1e-21 76.1 0.2 1.3e-05 24.9 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ27938.1 - 7.1e-05 22.6 4.2 0.3 11.3 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF727 PF05303.12 EEQ27938.1 - 0.0028 17.7 0.0 0.0091 16.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 EEQ27938.1 - 0.0028 17.7 4.4 0.14 12.4 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3734 PF12536.8 EEQ27938.1 - 0.16 12.3 0.8 10 6.5 0.1 2.8 2 0 0 2 2 2 0 Patatin phospholipase AAA_16 PF13191.6 EEQ27940.1 - 1.9e-06 28.4 0.6 6.5e-06 26.6 0.3 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EEQ27940.1 - 0.0021 18.5 0.0 0.077 13.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EEQ27940.1 - 0.0082 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 EEQ27940.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EEQ27940.1 - 0.027 13.6 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EEQ27940.1 - 0.086 12.8 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ27940.1 - 0.11 12.7 0.3 0.67 10.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain HTH_Tnp_Tc3_2 PF01498.18 EEQ27941.1 - 0.067 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Transposase DUF3504 PF12012.8 EEQ27941.1 - 0.49 10.3 2.2 1.9 8.4 2.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3504) Med10 PF09748.9 EEQ27942.1 - 4.7e-37 126.6 0.0 6.9e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 EEQ27942.1 - 0.0048 16.8 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) Peptidase_M28 PF04389.17 EEQ27944.1 - 1.4e-34 119.5 0.0 2.3e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.20 EEQ27944.1 - 0.054 14.0 0.0 0.054 14.0 0.0 3.8 4 0 0 4 4 4 0 ATP synthase protein 8 Peptidase_M20 PF01546.28 EEQ27944.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 LRR_6 PF13516.6 EEQ27945.1 - 9.3e-14 50.3 22.3 0.41 10.8 0.0 12.4 13 0 0 13 13 13 4 Leucine Rich repeat LRR_4 PF12799.7 EEQ27945.1 - 9.4e-12 45.0 10.5 0.86 10.1 0.0 8.0 3 2 7 10 10 10 7 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EEQ27945.1 - 3.7e-10 39.5 5.4 6.7e-09 35.5 0.7 3.1 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 EEQ27945.1 - 0.00011 21.9 4.5 0.00096 19.0 0.2 3.6 3 0 0 3 3 3 1 F-box domain Recep_L_domain PF01030.24 EEQ27945.1 - 0.076 13.1 0.7 23 5.1 0.0 3.7 1 1 2 4 4 4 0 Receptor L domain LRR_1 PF00560.33 EEQ27945.1 - 0.29 11.8 14.1 16 6.5 0.1 8.6 7 2 0 7 7 7 0 Leucine Rich Repeat UPF0731 PF14982.6 EEQ27945.1 - 0.61 10.3 2.9 63 3.9 0.0 4.1 4 1 1 5 5 5 0 UPF0731 family AMP-binding PF00501.28 EEQ27946.1 - 1.5e-70 238.0 0.0 1.8e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ27946.1 - 2.5e-18 66.8 0.0 6e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L13 PF00572.18 EEQ27947.1 - 5.7e-11 42.8 0.0 5.2e-09 36.4 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 Metallophos PF00149.28 EEQ27948.1 - 5.4e-15 56.4 1.4 5.6e-15 56.4 0.5 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEQ27948.1 - 2.4e-07 31.1 0.9 5.1e-05 23.5 0.0 2.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EEQ27948.1 - 0.025 13.9 0.0 1.7 7.9 0.0 2.6 2 1 1 3 3 3 0 Metallophosphoesterase, calcineurin superfamily MutL PF13941.6 EEQ27948.1 - 0.062 11.9 0.0 0.094 11.3 0.0 1.2 1 0 0 1 1 1 0 MutL protein Pyr_redox_2 PF07992.14 EEQ27949.1 - 4.3e-37 127.9 0.0 5.9e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ27949.1 - 5.8e-16 58.8 0.0 7.2e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ27949.1 - 1.5e-06 27.7 0.0 1.6e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ27949.1 - 1.5e-06 27.6 0.1 0.00011 21.5 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EEQ27949.1 - 0.0022 16.9 0.1 0.48 9.2 0.0 2.9 2 1 1 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.6 EEQ27949.1 - 0.0026 17.8 0.0 22 5.0 0.0 4.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 EEQ27949.1 - 0.0094 15.6 0.0 1.3 8.5 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EEQ27949.1 - 0.019 14.1 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Eno-Rase_NADH_b PF12242.8 EEQ27949.1 - 0.066 13.0 0.1 0.29 10.9 0.0 2.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_8 PF13450.6 EEQ27949.1 - 0.1 12.8 0.0 7 7.0 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.11 EEQ27949.1 - 0.18 11.4 0.0 0.43 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) DnaJ PF00226.31 EEQ27951.1 - 3.8e-21 75.0 0.5 7.3e-21 74.1 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Adaptin_N PF01602.20 EEQ27952.1 - 8.6e-133 443.7 0.0 1.6e-132 442.8 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EEQ27952.1 - 3.1e-21 75.8 0.0 6.4e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EEQ27952.1 - 4.7e-09 36.5 2.8 5.8e-05 23.2 0.0 3.7 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ27952.1 - 1.8e-07 31.4 0.3 0.0093 16.3 0.0 3.6 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EEQ27952.1 - 0.0005 20.1 2.1 6.5 7.3 0.1 4.3 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 EEQ27952.1 - 0.013 16.0 0.3 22 5.7 0.0 4.6 4 1 0 4 4 4 0 HEAT-like repeat RICTOR_M PF14666.6 EEQ27952.1 - 0.051 13.3 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Cohesin_HEAT PF12765.7 EEQ27952.1 - 0.16 12.3 0.2 0.55 10.6 0.2 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.23 EEQ27952.1 - 0.17 12.0 0.2 99 3.2 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat MBOAT PF03062.19 EEQ27953.1 - 1.7e-30 106.5 12.5 1.3e-28 100.3 8.5 2.2 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family EamA PF00892.20 EEQ27954.1 - 4.9e-09 36.5 25.9 4.2e-05 23.7 2.6 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EEQ27954.1 - 8.6e-09 35.0 0.1 1.3e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EEQ27954.1 - 5.7e-05 22.5 10.0 0.0001 21.6 10.0 1.4 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 EEQ27954.1 - 0.0002 20.8 7.0 0.00027 20.4 0.1 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family Med15_fungi PF05397.12 EEQ27955.1 - 7.1e-17 61.7 11.0 7.1e-17 61.7 11.0 5.4 6 1 0 6 6 6 1 Mediator complex subunit 15 LMBR1 PF04791.16 EEQ27956.1 - 7.6e-119 397.9 1.2 8.8e-119 397.7 1.2 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein BAG PF02179.16 EEQ27957.1 - 1.3e-06 28.7 0.3 1.3e-06 28.7 0.3 1.8 2 0 0 2 2 2 1 BAG domain DUF2407 PF10302.9 EEQ27957.1 - 0.037 14.6 0.0 0.12 13.0 0.0 1.9 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EEQ27957.1 - 0.13 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family CDC45 PF02724.14 EEQ27957.1 - 0.24 9.7 4.2 0.38 9.0 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4674 PF15719.5 EEQ27957.1 - 0.37 10.8 0.0 0.37 10.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4674) NOA36 PF06524.12 EEQ27957.1 - 4.6 6.5 6.4 9.8 5.4 6.4 1.5 1 0 0 1 1 1 0 NOA36 protein F-box PF00646.33 EEQ27958.1 - 0.0038 17.1 0.1 0.01 15.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain ING PF12998.7 EEQ27959.1 - 4.9e-07 30.3 0.0 1.3e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-C2H2 PF00096.26 EEQ27960.1 - 0.035 14.6 3.7 0.035 14.6 3.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ27960.1 - 4.8 8.3 7.4 1.7 9.7 3.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltransf_16 PF10294.9 EEQ27961.1 - 1.1e-08 35.0 0.0 1.9e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_31 PF13847.6 EEQ27962.1 - 7.6e-16 58.3 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ27962.1 - 5e-08 33.6 0.0 1.1e-06 29.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ27962.1 - 8.3e-06 25.7 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ27962.1 - 1.5e-05 25.6 0.0 3.8e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ27962.1 - 0.0057 17.4 0.0 0.013 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EEQ27962.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 EEQ27962.1 - 0.051 13.1 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain AMP-binding PF00501.28 EEQ27963.1 - 9.4e-138 459.3 0.0 7.6e-71 238.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EEQ27963.1 - 2.3e-104 349.6 0.0 7.5e-35 120.5 0.0 6.6 4 2 0 4 4 4 4 Condensation domain PP-binding PF00550.25 EEQ27963.1 - 3e-32 110.8 0.6 1.1e-11 44.9 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ27963.1 - 0.041 14.9 0.0 7.4 7.6 0.0 2.6 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain ABC_membrane PF00664.23 EEQ27964.1 - 1e-104 350.1 44.8 7.2e-57 193.1 20.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ27964.1 - 2.3e-70 235.4 0.1 1.8e-34 119.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ27964.1 - 7.8e-16 58.2 4.7 3.6e-06 26.6 0.8 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EEQ27964.1 - 8.8e-10 39.2 4.6 0.00067 20.1 1.6 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EEQ27964.1 - 2.6e-08 34.0 0.1 0.00017 21.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ27964.1 - 8.8e-08 32.2 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EEQ27964.1 - 4.7e-07 29.5 0.1 0.0091 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ27964.1 - 1.7e-06 28.4 0.7 0.018 15.3 0.1 4.1 3 2 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EEQ27964.1 - 2.5e-06 27.6 0.2 0.0031 17.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 EEQ27964.1 - 2.9e-06 26.4 0.5 0.017 14.0 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 EEQ27964.1 - 5.3e-05 23.0 2.2 0.21 11.3 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.14 EEQ27964.1 - 7.6e-05 22.7 0.7 0.38 10.7 0.0 3.9 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EEQ27964.1 - 0.00011 21.6 0.3 0.34 10.2 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_7 PF12775.7 EEQ27964.1 - 0.00045 19.8 0.0 0.3 10.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 EEQ27964.1 - 0.00046 20.6 0.3 31 5.0 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 EEQ27964.1 - 0.0011 18.2 0.1 0.21 10.7 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_18 PF13238.6 EEQ27964.1 - 0.0016 19.0 0.0 0.081 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EEQ27964.1 - 0.0017 18.6 0.6 6.3 7.1 0.2 3.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EEQ27964.1 - 0.0028 17.6 0.2 0.42 10.5 0.0 2.9 4 0 0 4 4 2 1 Rad17 P-loop domain AAA_23 PF13476.6 EEQ27964.1 - 0.0055 17.2 0.0 4.4 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EEQ27964.1 - 0.009 15.6 0.1 4.8 6.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EEQ27964.1 - 0.01 15.0 0.0 1.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EEQ27964.1 - 0.011 15.8 0.0 0.59 10.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EEQ27964.1 - 0.013 15.3 0.0 0.61 9.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EEQ27964.1 - 0.035 13.8 0.1 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EEQ27964.1 - 0.035 14.0 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_14 PF13173.6 EEQ27964.1 - 0.039 14.0 0.1 4.1 7.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain Roc PF08477.13 EEQ27964.1 - 0.042 14.1 0.2 37 4.5 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EEQ27964.1 - 0.061 13.4 2.4 3.1 7.9 0.2 3.5 3 1 0 3 3 3 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EEQ27964.1 - 0.066 13.6 0.1 10 6.6 0.0 3.2 4 0 0 4 4 2 0 RNA helicase DUF3987 PF13148.6 EEQ27964.1 - 0.073 12.1 0.0 2.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_28 PF13521.6 EEQ27964.1 - 0.095 12.9 0.7 4.2 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EEQ27964.1 - 0.1 12.0 0.3 27 4.1 0.0 3.8 5 0 0 5 5 4 0 Bacterial TniB protein IstB_IS21 PF01695.17 EEQ27964.1 - 0.21 11.3 1.3 13 5.5 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein Dynamin_N PF00350.23 EEQ27964.1 - 0.23 11.5 1.1 41 4.2 0.0 4.2 5 0 0 5 5 4 0 Dynamin family MoaE PF02391.17 EEQ27964.1 - 0.34 11.2 1.3 12 6.2 0.3 2.8 2 0 0 2 2 2 0 MoaE protein Beta-lactamase PF00144.24 EEQ27965.1 - 1.5e-46 159.2 0.0 2e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EEQ27965.1 - 6.8e-09 36.1 0.1 1.3e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DSPc PF00782.20 EEQ27966.1 - 9.6e-24 83.7 0.0 4e-21 75.2 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEQ27966.1 - 0.066 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Epimerase PF01370.21 EEQ27970.1 - 2.2e-14 53.5 0.1 2.4e-13 50.1 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ27970.1 - 6.3e-11 41.8 0.0 6.5e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EEQ27970.1 - 1.5e-09 37.7 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EEQ27970.1 - 1.8e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EEQ27970.1 - 3e-06 27.3 0.0 4.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EEQ27970.1 - 9.8e-06 24.9 0.0 2.7e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EEQ27970.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EEQ27970.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EEQ27970.1 - 0.0091 15.6 0.2 0.061 12.9 0.1 2.1 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EEQ27970.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DSBA PF01323.20 EEQ27971.1 - 3.3e-35 121.6 0.0 3.7e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EEQ27971.1 - 0.0072 16.5 0.1 0.026 14.7 0.0 1.9 3 0 0 3 3 3 1 Thioredoxin Pkinase PF00069.25 EEQ27972.1 - 2.8e-25 89.2 0.0 9.6e-25 87.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27972.1 - 2.1e-10 40.3 0.0 3.4e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RMP PF14996.6 EEQ27973.1 - 0.0048 17.1 2.4 0.0059 16.8 1.8 1.4 1 1 0 1 1 1 1 Retinal Maintenance KH_1 PF00013.29 EEQ27974.1 - 4.3e-41 138.6 9.0 6.3e-17 61.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EEQ27974.1 - 1.4e-09 37.7 9.1 0.0016 18.2 0.6 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 EEQ27974.1 - 8.4e-09 35.2 3.9 0.025 14.5 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EEQ27974.1 - 0.00089 19.3 6.8 0.29 11.3 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain ECF-ribofla_trS PF07155.12 EEQ27974.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component Dehydratase_hem PF13816.6 EEQ27975.1 - 1e-113 379.9 0.0 1.2e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 EEQ27975.1 - 1e-07 32.3 0.0 0.021 15.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) ADH_N PF08240.12 EEQ27976.1 - 9.4e-29 99.5 0.8 1.5e-28 98.8 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ27976.1 - 2.6e-17 63.0 0.0 3.9e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EEQ27976.1 - 6.2e-06 25.8 0.0 9.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EEQ27976.1 - 0.028 15.4 0.0 0.051 14.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EEQ27976.1 - 0.061 13.3 0.1 0.21 11.5 0.1 2.0 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 EEQ27976.1 - 0.064 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Yippee-Mis18 PF03226.14 EEQ27977.1 - 1e-17 64.2 0.4 1.2e-17 64.0 0.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EEQ27977.1 - 0.0013 19.0 2.2 0.0017 18.5 2.2 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.9 EEQ27977.1 - 0.0047 17.2 1.9 0.04 14.3 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) DUF4451 PF14616.6 EEQ27977.1 - 0.016 15.4 2.3 0.025 14.8 2.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) Evr1_Alr PF04777.13 EEQ27977.1 - 0.17 12.3 2.4 2 8.9 0.3 2.1 1 1 1 2 2 2 0 Erv1 / Alr family RabGAP-TBC PF00566.18 EEQ27979.1 - 1.6e-21 77.0 4.9 1.6e-21 77.0 4.9 2.2 2 1 0 2 2 2 1 Rab-GTPase-TBC domain COesterase PF00135.28 EEQ27981.1 - 2.9e-77 260.7 0.0 4.2e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EEQ27981.1 - 8.3e-07 29.1 0.0 0.00031 20.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ27981.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.25 EEQ27982.1 - 1e-54 185.7 0.0 1.5e-54 185.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ27982.1 - 1.8e-19 70.0 0.0 3.3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ27982.1 - 8.8e-05 21.6 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEQ27982.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ27982.1 - 0.00011 21.6 0.0 0.00032 20.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EEQ27982.1 - 0.00062 19.8 0.1 0.0014 18.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EEQ27982.1 - 0.0049 16.5 0.4 0.012 15.3 0.3 1.5 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EEQ27982.1 - 0.0082 15.0 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EEQ27982.1 - 0.038 13.6 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Dicistro_VP4 PF11492.8 EEQ27982.1 - 0.19 11.7 0.0 0.58 10.2 0.0 1.8 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 F-box-like PF12937.7 EEQ27983.1 - 6e-11 42.1 0.0 2.6e-10 40.0 0.0 2.2 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EEQ27983.1 - 2.2e-10 39.7 18.4 0.0047 16.9 0.0 7.8 9 0 0 9 9 9 3 Leucine Rich repeat F-box PF00646.33 EEQ27983.1 - 4.8e-10 39.1 0.0 1.6e-09 37.4 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EEQ27983.1 - 7.2e-07 29.4 12.1 0.063 13.7 0.2 6.3 4 1 3 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EEQ27983.1 - 0.004 17.5 15.2 9.6 7.2 0.2 8.0 8 0 0 8 8 8 1 Leucine Rich Repeat PRANC PF09372.10 EEQ27983.1 - 0.0069 16.7 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 PRANC domain LRR_8 PF13855.6 EEQ27983.1 - 0.11 12.2 3.6 95 2.9 0.1 4.5 3 2 1 4 4 4 0 Leucine rich repeat Efg1 PF10153.9 EEQ27984.1 - 1.5e-33 115.6 8.9 1.5e-33 115.6 8.9 2.3 3 0 0 3 3 3 1 rRNA-processing protein Efg1 DUF573 PF04504.14 EEQ27984.1 - 0.046 14.4 0.6 0.046 14.4 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function, DUF573 zinc_ribbon_16 PF17034.5 EEQ27985.1 - 7.8e-07 29.4 0.5 2.1e-06 27.9 0.5 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family APH PF01636.23 EEQ27986.1 - 2.5e-08 34.1 0.0 4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ27986.1 - 0.0095 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EEQ27986.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF4058 PF13267.6 EEQ27987.1 - 0.0041 16.6 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4058) PTS_2-RNA PF01885.16 EEQ27988.1 - 3.7e-64 216.1 0.0 4.5e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family APH PF01636.23 EEQ27989.1 - 2.7e-15 57.0 0.0 7.5e-13 49.0 0.0 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family LON_substr_bdg PF02190.16 EEQ27989.1 - 0.041 13.8 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Alkyl_sulf_dimr PF14863.6 EEQ27990.1 - 6.6e-54 182.1 0.1 1.4e-53 181.1 0.1 1.6 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.6 EEQ27990.1 - 2.9e-36 124.5 0.1 5.6e-36 123.6 0.1 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.27 EEQ27990.1 - 1.5e-27 96.9 0.0 2.4e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EEQ27990.1 - 3e-06 26.9 0.0 7.9e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 EEQ27990.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II TT_ORF1 PF02956.14 EEQ27991.1 - 8.8 4.9 7.0 10 4.7 7.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 Stb3 PF10330.9 EEQ27992.1 - 1e-37 128.0 0.0 1.7e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Mito_carr PF00153.27 EEQ27994.1 - 4.9e-67 221.9 5.8 5.5e-25 87.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kri1 PF05178.12 EEQ27995.1 - 1.3e-30 106.0 19.2 1.3e-30 106.0 19.2 5.4 5 1 0 5 5 5 1 KRI1-like family Kri1_C PF12936.7 EEQ27995.1 - 1.1e-28 99.2 0.2 1.1e-28 99.2 0.2 4.1 2 2 2 4 4 4 1 KRI1-like family C-terminal VASt PF16016.5 EEQ27996.1 - 4.5e-37 127.8 0.1 1.2e-36 126.4 0.1 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EEQ27996.1 - 4.3e-15 56.1 0.2 6.9e-15 55.4 0.2 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EEQ27996.1 - 5.8e-08 33.2 0.0 2.5e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 PH domain BAR PF03114.18 EEQ27996.1 - 0.011 15.4 2.0 0.019 14.6 2.0 1.4 1 0 0 1 1 1 0 BAR domain GRAM PF02893.20 EEQ27996.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Sen15 PF09631.10 EEQ27997.1 - 3e-14 53.1 0.0 6.6e-14 52.0 0.0 1.5 1 1 0 1 1 1 1 Sen15 protein DUF4452 PF14618.6 EEQ27997.1 - 0.22 11.4 1.2 0.37 10.6 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) UAA PF08449.11 EEQ27998.1 - 5.5e-43 147.3 11.8 1.6e-42 145.7 11.8 1.7 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EEQ27998.1 - 1.4e-07 31.0 0.1 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 EEQ27998.1 - 8.6e-06 26.0 31.4 3.6e-05 23.9 10.5 3.8 3 1 0 3 3 3 2 EamA-like transporter family Rotamase_3 PF13616.6 EEQ27999.1 - 3.9e-15 56.4 0.1 7.8e-15 55.4 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EEQ27999.1 - 3.2e-14 53.6 0.0 5e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EEQ27999.1 - 0.00043 21.1 0.0 0.00052 20.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF3883 PF13020.6 EEQ27999.1 - 0.025 14.6 0.0 0.037 14.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3883) Gram_pos_anchor PF00746.21 EEQ28000.1 - 0.72 9.8 3.7 2.1 8.3 3.7 1.9 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DAO PF01266.24 EEQ28002.1 - 3.9e-44 151.7 2.1 4.8e-44 151.4 2.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EEQ28002.1 - 7.2e-06 26.1 0.4 0.015 15.3 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EEQ28002.1 - 9.3e-06 25.8 1.1 2.7e-05 24.3 1.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EEQ28002.1 - 0.0014 17.9 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EEQ28002.1 - 0.0014 17.9 0.0 0.043 13.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ28002.1 - 0.0072 15.6 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ28002.1 - 0.014 14.5 0.3 0.048 12.7 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EEQ28002.1 - 0.041 12.9 6.2 0.095 11.8 6.2 1.5 1 1 0 1 1 1 0 FAD binding domain GIT_CC PF16559.5 EEQ28003.1 - 0.033 14.1 3.0 0.42 10.5 1.5 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 EEQ28003.1 - 0.23 11.5 7.5 0.53 10.4 7.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus 2OG-FeII_Oxy_2 PF13532.6 EEQ28005.1 - 7.7e-12 45.8 0.0 2.5e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.16 EEQ28006.1 - 1.4e-08 34.8 0.6 1.4e-08 34.8 0.6 2.1 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ank_2 PF12796.7 EEQ28007.1 - 6.3e-25 87.6 0.1 9e-13 48.6 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ28007.1 - 1.3e-22 79.5 0.4 1.7e-09 37.8 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ28007.1 - 5.8e-15 55.5 0.0 3.1e-07 30.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EEQ28007.1 - 1.9e-13 50.2 0.2 0.0011 19.3 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EEQ28007.1 - 4.7e-12 45.0 0.7 0.00015 21.9 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat His_Phos_1 PF00300.22 EEQ28008.1 - 5.8e-30 104.4 0.0 7.4e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L7Ae PF01248.26 EEQ28009.1 - 6.6e-26 89.9 0.6 8.6e-26 89.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EEQ28009.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Vac_ImportDeg PF09783.9 EEQ28010.1 - 3e-17 62.9 0.1 1e-16 61.2 0.0 1.8 2 0 0 2 2 2 1 Vacuolar import and degradation protein MR_MLE_C PF13378.6 EEQ28011.1 - 1.1e-13 51.3 0.0 1.6e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like IU_nuc_hydro PF01156.19 EEQ28012.1 - 2.9e-69 234.0 0.0 3.4e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PXA PF02194.15 EEQ28013.1 - 3.5e-45 154.2 0.0 5e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 PXA domain DUF3082 PF11282.8 EEQ28013.1 - 0.075 13.3 0.2 4.3 7.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) HTH_Tnp_Tc5 PF03221.16 EEQ28015.1 - 1.8e-14 53.5 0.1 3.4e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EEQ28015.1 - 8e-06 25.4 0.0 1.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 EEQ28015.1 - 0.0072 16.2 0.0 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 EEQ28015.1 - 0.0089 16.0 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.16 EEQ28015.1 - 0.016 14.7 0.1 0.038 13.5 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 EEQ28015.1 - 0.13 12.1 0.1 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.6 EEQ28015.1 - 0.14 11.9 1.2 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain MMR_HSR1_Xtn PF16897.5 EEQ28016.1 - 1.9e-39 133.9 0.6 6.9e-39 132.1 0.2 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EEQ28016.1 - 1.6e-22 79.3 0.0 3.2e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EEQ28016.1 - 3.7e-18 65.7 0.1 1.3e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ28016.1 - 1.4e-05 24.7 0.1 8.2e-05 22.2 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EEQ28016.1 - 0.00099 19.2 0.2 0.19 11.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EEQ28016.1 - 0.0057 15.7 0.1 0.029 13.3 0.2 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EEQ28016.1 - 0.13 12.4 0.0 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EEQ28016.1 - 0.24 11.3 1.8 3.9 7.4 0.1 2.8 2 2 1 3 3 3 0 RsgA GTPase CDO_I PF05995.12 EEQ28017.1 - 1.1e-40 138.7 0.0 1.3e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EEQ28017.1 - 7.7e-07 28.8 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO Cupin_7 PF12973.7 EEQ28017.1 - 0.026 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain TSSC4 PF15264.6 EEQ28017.1 - 0.14 12.4 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Glyco_transf_90 PF05686.12 EEQ28019.1 - 7.6e-14 51.4 10.7 3.7e-11 42.6 8.2 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_6 PF12697.7 EEQ28020.1 - 4e-14 53.8 0.0 4e-13 50.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ28020.1 - 7.5e-12 45.4 0.0 5.7e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ28020.1 - 5.1e-05 22.7 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EEQ28020.1 - 0.016 15.0 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase EHN PF06441.12 EEQ28020.1 - 0.026 14.9 0.2 0.054 13.9 0.2 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF1651 PF07864.11 EEQ28020.1 - 0.045 14.1 0.1 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) Med10 PF09748.9 EEQ28020.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Glyco_transf_8 PF01501.20 EEQ28021.1 - 2.4e-25 89.6 0.0 6e-25 88.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 HEAT PF02985.22 EEQ28022.1 - 5.7e-42 138.1 12.4 0.015 15.5 0.1 12.9 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.6 EEQ28022.1 - 8e-37 125.5 3.0 9.1e-10 38.8 0.0 8.3 4 2 4 8 8 8 8 HEAT repeats HEAT_EZ PF13513.6 EEQ28022.1 - 1.9e-15 57.0 7.5 0.00015 22.2 0.0 9.0 7 3 3 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EEQ28022.1 - 2.7e-11 43.9 3.7 0.00061 20.3 0.2 7.2 6 2 4 10 10 10 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EEQ28022.1 - 1.3e-10 41.5 11.1 0.0016 18.5 0.4 6.0 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EEQ28022.1 - 1.1e-08 34.1 5.4 1.8e-07 30.1 1.2 3.6 2 1 1 3 3 3 1 Adaptin N terminal region RTP1_C1 PF10363.9 EEQ28022.1 - 0.00011 22.3 5.0 1.1 9.5 0.1 4.8 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EEQ28022.1 - 0.0065 16.1 3.0 2.5 7.6 0.2 4.4 5 1 1 6 6 6 1 CLASP N terminal TetR_C_16 PF17920.1 EEQ28022.1 - 0.13 12.5 0.5 19 5.6 0.0 3.3 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain IFRD PF05004.13 EEQ28022.1 - 0.18 10.9 0.8 1.9 7.5 0.1 3.0 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) Trp_Tyr_perm PF03222.13 EEQ28022.1 - 0.19 10.7 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Arm PF00514.23 EEQ28022.1 - 0.25 11.5 6.4 2 8.6 0.0 4.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 EEQ28022.1 - 1.4 7.7 5.2 1.9 7.2 2.2 2.8 2 1 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) tRNA_synthFbeta PF17759.1 EEQ28023.1 - 1.6e-49 168.3 0.0 2.3e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 EEQ28023.1 - 1.1e-24 87.0 0.1 2.1e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EEQ28023.1 - 3.8e-16 59.1 0.0 2.1e-14 53.6 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain PhetRS_B1 PF18262.1 EEQ28023.1 - 1.6e-14 53.9 0.0 1.6e-10 41.0 0.0 3.4 3 0 0 3 3 3 2 Phe-tRNA synthetase beta subunit B1 domain DUF2740 PF10872.8 EEQ28023.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) tRNA-synt_2d PF01409.20 EEQ28023.1 - 0.15 11.5 0.0 1.1 8.7 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Ribosomal_S3_C PF00189.20 EEQ28024.1 - 4e-25 88.1 0.1 2e-24 85.9 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EEQ28024.1 - 6.6e-12 45.1 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 EEQ28024.1 - 0.074 12.8 0.1 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 EEQ28024.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.14 EEQ28025.1 - 2.3e-149 497.1 0.0 2.8e-149 496.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EEQ28025.1 - 0.0014 18.6 0.1 0.0031 17.5 0.1 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EEQ28025.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SLS PF14611.6 EEQ28026.1 - 2.1e-35 122.6 0.1 3.3e-35 121.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Pkinase PF00069.25 EEQ28027.1 - 9.9e-30 103.8 0.0 1.3e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28027.1 - 1.3e-24 86.9 0.0 2.4e-24 86.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ28027.1 - 7.3e-06 25.5 0.1 1.1e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 EEQ28027.1 - 9.5e-05 21.4 0.0 0.00013 21.0 0.0 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kinase-like PF14531.6 EEQ28027.1 - 0.00011 21.6 0.0 0.00026 20.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EEQ28027.1 - 0.00041 20.0 0.0 0.00058 19.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 EEQ28027.1 - 0.0038 16.3 1.1 0.11 11.6 0.3 2.3 2 1 0 2 2 2 1 Seadornavirus VP7 PIP49_C PF12260.8 EEQ28027.1 - 0.0053 16.4 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 APH PF01636.23 EEQ28027.1 - 0.019 14.9 0.1 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ28027.1 - 0.044 13.4 1.1 0.41 10.2 1.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase Bromodomain PF00439.25 EEQ28027.1 - 0.044 13.8 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Bromodomain NT-C2 PF10358.9 EEQ28028.1 - 1.7e-31 108.9 0.0 2.4e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3584 PF12128.8 EEQ28029.1 - 0.0039 14.8 6.5 0.0043 14.7 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF99 PF01949.16 EEQ28029.1 - 0.082 12.3 1.2 0.1 12.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF99 SpecificRecomb PF10136.9 EEQ28029.1 - 0.31 9.3 2.5 0.38 9.0 2.5 1.0 1 0 0 1 1 1 0 Site-specific recombinase Atg14 PF10186.9 EEQ28029.1 - 2.3 7.2 9.9 2.9 6.9 9.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS6_N PF14661.6 EEQ28029.1 - 2.8 7.4 11.6 3.6 7.1 11.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SF3b10 PF07189.11 EEQ28032.1 - 9.3e-34 115.4 0.0 1e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) A_deamin PF02137.18 EEQ28034.1 - 2e-24 86.7 0.1 1.3e-10 41.3 0.2 3.0 3 0 0 3 3 3 2 Adenosine-deaminase (editase) domain ERG4_ERG24 PF01222.17 EEQ28035.1 - 1.1e-133 446.1 2.3 1.4e-133 445.8 2.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EEQ28035.1 - 0.00017 21.2 0.9 0.00041 19.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.15 EEQ28036.1 - 4.9e-13 48.7 0.0 5.6e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EEQ28036.1 - 5.9e-09 36.2 0.0 4.1e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 EEQ28036.1 - 3.6e-08 33.6 0.1 3.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Astro_capsid_p PF12226.8 EEQ28036.1 - 0.69 9.0 2.4 0.88 8.7 2.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sigma70_ner PF04546.13 EEQ28036.1 - 1.5 8.7 5.7 2.1 8.2 5.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 EEQ28036.1 - 4.7 5.4 8.3 6.5 4.9 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans PF04082.18 EEQ28037.1 - 4.9e-24 84.8 0.0 1.1e-23 83.6 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ28037.1 - 2.9e-06 27.3 8.8 6.1e-06 26.3 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 EEQ28037.1 - 0.0033 17.1 20.2 0.0033 17.1 20.2 2.4 2 0 0 2 2 2 1 Spt20 family TFIIA PF03153.13 EEQ28037.1 - 0.0061 16.6 13.6 0.0061 16.6 13.6 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 EEQ28037.1 - 0.63 10.2 10.0 0.74 9.9 5.0 2.3 2 0 0 2 2 2 0 DDHD domain DUF4407 PF14362.6 EEQ28037.1 - 2.5 7.4 6.5 4.1 6.7 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4175 PF13779.6 EEQ28037.1 - 6.9 4.4 21.0 0.0082 14.1 10.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Band_3_cyto PF07565.13 EEQ28037.1 - 8 6.2 10.5 0.16 11.8 2.3 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain RR_TM4-6 PF06459.12 EEQ28037.1 - 9.6 5.9 14.5 3.2 7.5 6.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SKG6 PF08693.10 EEQ28038.1 - 2.1e-06 27.0 0.1 2.1e-06 27.0 0.1 2.0 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Cation_efflux PF01545.21 EEQ28038.1 - 0.097 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family DUF4381 PF14316.6 EEQ28038.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Alpha_GJ PF03229.13 EEQ28038.1 - 1.4 9.5 5.8 6.1 7.4 0.0 2.2 1 1 1 2 2 2 0 Alphavirus glycoprotein J Glyco_hydro_47 PF01532.20 EEQ28039.1 - 2.5e-179 597.0 0.0 2.9e-179 596.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 EEQ28039.1 - 0.089 11.3 0.0 2.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Rap1_C PF11626.8 EEQ28039.1 - 0.15 12.1 0.0 3.4 7.8 0.0 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Glyco_hydro_3_C PF01915.22 EEQ28040.1 - 2.2e-50 171.5 0.1 5.6e-50 170.1 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EEQ28040.1 - 3.6e-37 128.4 0.0 7e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EEQ28040.1 - 2.9e-13 49.7 0.0 5.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain TbpB_B_D PF01298.18 EEQ28041.1 - 0.047 14.1 0.2 0.059 13.8 0.2 1.1 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Pkinase PF00069.25 EEQ28042.1 - 1.2e-29 103.5 0.0 5e-28 98.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28042.1 - 0.0012 18.2 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase tRNA-synt_1e PF01406.19 EEQ28043.1 - 4.8e-21 75.4 0.2 3.6e-16 59.4 0.3 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Zn_clus PF00172.18 EEQ28045.1 - 0.0062 16.6 12.3 0.013 15.6 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Scs3p PF10261.9 EEQ28046.1 - 2.9e-69 233.3 2.5 4e-69 232.9 2.5 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Erythro_esteras PF05139.14 EEQ28048.1 - 5e-124 414.6 1.1 5.8e-124 414.4 1.1 1.0 1 0 0 1 1 1 1 Erythromycin esterase Cofac_haem_bdg PF04187.13 EEQ28048.1 - 0.00024 21.2 0.9 0.25 11.3 0.1 2.2 2 0 0 2 2 2 2 Haem-binding uptake, Tiki superfamily, ChaN Glyco_hydro_99 PF16317.5 EEQ28048.1 - 0.067 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 Mannitol_dh PF01232.23 EEQ28048.1 - 0.19 11.9 0.0 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain DUF3535 PF12054.8 EEQ28050.1 - 1.4e-128 429.9 0.0 4e-127 425.1 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EEQ28050.1 - 8.5e-64 215.5 0.0 2.5e-63 213.9 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ28050.1 - 1.8e-19 70.1 0.0 5.9e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EEQ28050.1 - 5.8e-18 63.5 8.4 0.0014 18.7 0.2 9.5 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.7 EEQ28050.1 - 5.7e-06 26.8 0.2 0.56 10.8 0.0 4.1 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EEQ28050.1 - 1.9e-05 25.0 11.2 0.00074 19.9 0.6 6.3 8 0 0 8 8 8 1 HEAT repeats CLASP_N PF12348.8 EEQ28050.1 - 0.00017 21.2 0.0 0.036 13.6 0.0 3.6 3 1 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 EEQ28050.1 - 0.00053 20.4 7.3 7.6 7.2 0.0 7.5 7 0 0 7 7 7 1 HEAT-like repeat TAF6_C PF07571.13 EEQ28050.1 - 0.00082 19.6 0.0 0.35 11.2 0.0 4.7 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EEQ28050.1 - 0.045 13.9 0.0 0.91 9.7 0.0 3.3 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec39 PF08314.11 EEQ28051.1 - 2.4e-267 889.3 0.0 2.7e-267 889.1 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Pkinase PF00069.25 EEQ28052.1 - 3e-63 213.7 0.0 3.6e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28052.1 - 8.7e-35 120.2 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ28052.1 - 5.8e-07 29.1 0.0 9.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ28052.1 - 0.00015 20.7 0.0 0.00025 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EEQ28052.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CN_hydrolase PF00795.22 EEQ28053.1 - 6.5e-39 133.8 0.0 8.6e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EEQ28053.1 - 5.3e-25 87.9 0.0 1.1e-24 86.9 0.0 1.5 1 1 0 1 1 1 1 NAD synthase Protoglobin PF11563.8 EEQ28054.1 - 4.8e-43 146.8 0.0 5.9e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Protoglobin AAA PF00004.29 EEQ28063.1 - 3.3e-18 66.4 0.0 6.7e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ28063.1 - 5.2e-05 23.7 0.9 0.00025 21.4 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EEQ28063.1 - 0.00074 19.8 0.1 0.0037 17.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EEQ28063.1 - 0.0016 18.5 0.0 0.0054 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ28063.1 - 0.025 14.7 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 EEQ28063.1 - 0.035 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEQ28063.1 - 0.036 14.1 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ28063.1 - 0.036 14.6 0.0 0.1 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EEQ28063.1 - 0.051 13.9 0.2 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EEQ28063.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EEQ28063.1 - 0.058 12.7 0.0 3.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EEQ28063.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EEQ28063.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EEQ28063.1 - 0.13 11.9 0.0 0.85 9.3 0.0 2.1 1 1 1 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EEQ28063.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PRY PF13765.6 EEQ28064.1 - 0.2 11.3 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 SPRY-associated domain Pkinase_fungal PF17667.1 EEQ28065.1 - 1.9e-113 379.3 0.0 4.2e-113 378.2 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EEQ28065.1 - 0.043 13.2 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 EEQ28067.1 - 0.0086 16.0 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family PI3_PI4_kinase PF00454.27 EEQ28067.1 - 0.043 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Aspzincin_M35 PF14521.6 EEQ28069.1 - 9.7e-08 32.7 0.0 3.4e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase TPR_2 PF07719.17 EEQ28070.1 - 1.5e-28 96.5 4.9 1.6e-06 27.8 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ28070.1 - 2.2e-28 96.8 9.0 6.8e-07 28.8 0.1 7.1 7 1 1 8 8 8 4 Tetratricopeptide repeat DnaJ PF00226.31 EEQ28070.1 - 1e-26 92.8 2.4 3e-26 91.3 1.2 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 EEQ28070.1 - 9.5e-22 77.3 7.7 0.00016 22.1 0.8 5.4 3 3 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ28070.1 - 7.5e-18 63.6 2.2 0.0094 16.3 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ28070.1 - 5.8e-16 57.3 3.3 0.001 19.1 0.0 6.1 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ28070.1 - 5.9e-16 57.8 15.5 0.00052 20.6 0.0 8.2 5 2 4 9 9 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ28070.1 - 9.2e-16 57.3 11.0 1.8e-05 24.3 0.0 6.7 5 2 2 7 7 6 3 TPR repeat TPR_7 PF13176.6 EEQ28070.1 - 7.9e-14 50.6 7.2 0.023 14.7 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ28070.1 - 2.1e-12 47.4 13.8 0.00082 20.0 0.0 6.1 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ28070.1 - 9.7e-12 45.0 4.1 0.037 14.3 0.0 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ28070.1 - 3e-11 43.4 0.6 0.0032 17.7 0.1 3.9 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EEQ28070.1 - 7e-10 38.9 2.0 0.0092 16.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ28070.1 - 4.4e-09 36.4 10.6 0.0008 19.9 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EEQ28070.1 - 2.5e-06 26.9 1.0 0.033 13.4 0.0 4.1 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ28070.1 - 1.6e-05 24.6 4.2 0.2 11.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 EEQ28070.1 - 0.00039 20.9 4.2 0.13 12.7 0.7 3.9 3 1 1 4 4 4 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 EEQ28070.1 - 0.015 15.6 6.2 5 7.5 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EEQ28070.1 - 0.016 15.3 2.1 7.1 6.8 0.0 3.7 3 2 2 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 EEQ28070.1 - 0.057 12.8 0.2 22 4.3 0.0 2.8 2 1 0 2 2 2 0 MalT-like TPR region TPR_4 PF07721.14 EEQ28070.1 - 0.062 14.0 15.4 0.44 11.3 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat HHH_8 PF14716.6 EEQ28070.1 - 0.076 13.4 2.6 1.9 8.9 0.1 3.8 4 0 0 4 4 3 0 Helix-hairpin-helix domain DUF5588 PF17826.1 EEQ28070.1 - 0.092 11.6 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5588) TPR_21 PF09976.9 EEQ28070.1 - 0.13 12.0 1.9 19 4.9 0.0 3.8 2 2 1 4 4 4 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 EEQ28070.1 - 0.45 10.2 3.1 6.8 6.4 0.0 3.5 2 2 1 3 3 3 0 26S proteasome subunit RPN7 DUF4451 PF14616.6 EEQ28071.1 - 3.9e-22 78.7 0.6 1.1e-21 77.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) APH PF01636.23 EEQ28072.1 - 2.2e-10 40.9 0.0 4.8e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EEQ28072.1 - 0.00043 19.7 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EEQ28072.1 - 0.01 14.7 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EEQ28072.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box PF00646.33 EEQ28073.1 - 5.9e-06 26.0 5.1 7.1e-06 25.8 1.6 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EEQ28073.1 - 2.2e-05 24.2 0.5 8.2e-05 22.4 0.5 2.1 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EEQ28073.1 - 0.00011 22.1 0.1 0.00022 21.1 0.1 1.5 1 0 0 1 1 1 1 F-box Kdo PF06293.14 EEQ28074.1 - 1.7e-05 24.3 0.1 3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEQ28074.1 - 0.00039 19.9 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EEQ28074.1 - 0.0005 20.1 0.3 0.00085 19.3 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EEQ28074.1 - 0.0046 16.6 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EEQ28074.1 - 0.021 14.4 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EEQ28075.1 - 3.2e-17 63.2 0.0 5.7e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ28075.1 - 1.5e-05 24.7 0.3 0.00052 19.7 0.3 2.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ28075.1 - 6.1e-05 22.5 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Sugar_tr PF00083.24 EEQ28076.1 - 4.2e-85 286.3 28.2 4.9e-85 286.1 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ28076.1 - 2.3e-14 53.1 36.7 1.2e-10 40.8 17.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Ceramidase_alk PF04734.13 EEQ28077.1 - 0.22 10.1 0.2 0.34 9.5 0.2 1.2 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal Pkinase PF00069.25 EEQ28079.1 - 5.7e-39 134.1 0.0 8.5e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28079.1 - 4.2e-26 91.8 0.0 6.2e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ28079.1 - 0.0037 16.6 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ28079.1 - 0.0099 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1687 PF07955.11 EEQ28079.1 - 0.085 13.3 0.0 0.3 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Ras PF00071.22 EEQ28080.1 - 3e-55 186.3 0.0 3.7e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ28080.1 - 5.3e-34 117.0 0.0 7.4e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ28080.1 - 4.7e-13 49.0 0.0 7.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ28080.1 - 0.00017 21.0 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EEQ28080.1 - 0.00024 20.7 0.0 0.0004 20.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEQ28080.1 - 0.00033 20.7 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ28080.1 - 0.0015 19.0 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Acetate_kinase PF00871.17 EEQ28084.1 - 7.6e-87 291.5 0.2 9e-87 291.3 0.2 1.0 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.10 EEQ28085.1 - 5e-149 496.0 0.0 6.8e-149 495.6 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EEQ28085.1 - 9.4e-78 260.3 0.0 1.3e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EEQ28085.1 - 2.4e-62 209.8 0.3 9.2e-60 201.4 0.3 2.3 1 1 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Ribosomal_S7e PF01251.18 EEQ28086.1 - 3.4e-79 264.9 0.2 4e-79 264.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.13 EEQ28087.1 - 4.5e-204 678.7 0.1 5.4e-204 678.4 0.1 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF5473 PF17567.2 EEQ28087.1 - 0.12 12.7 0.7 0.27 11.5 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5473) Methyltransf_11 PF08241.12 EEQ28088.1 - 5.2e-09 36.6 0.0 1.1e-08 35.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ28088.1 - 8.5e-09 35.5 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ28088.1 - 9.7e-07 29.4 0.0 3.2e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ28088.1 - 9.4e-06 26.3 0.0 1.9e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ28088.1 - 0.00028 20.7 0.0 0.00072 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ28088.1 - 0.00081 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family P16-Arc PF04699.14 EEQ28089.1 - 4.6e-46 157.0 0.0 5.2e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Cation_ATPase_C PF00689.21 EEQ28090.1 - 3.2e-47 160.6 11.0 3.2e-47 160.6 11.0 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EEQ28090.1 - 3.6e-32 111.3 0.0 3.6e-32 111.3 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EEQ28090.1 - 4.1e-21 74.9 0.0 7.6e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEQ28090.1 - 4.1e-13 50.1 0.0 1.3e-12 48.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEQ28090.1 - 1.3e-08 34.4 0.3 8.9e-08 31.7 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEQ28090.1 - 0.00061 19.6 0.1 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1774 PF08611.10 EEQ28090.1 - 0.072 13.4 5.1 0.3 11.4 0.2 2.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Ferlin_C PF16165.5 EEQ28090.1 - 0.092 12.7 0.7 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 Ferlin C-terminus GFO_IDH_MocA PF01408.22 EEQ28092.1 - 9.1e-08 32.9 0.3 3e-07 31.3 0.3 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.22 EEQ28093.1 - 7.6e-32 110.2 0.0 5e-31 107.5 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family WD40 PF00400.32 EEQ28094.1 - 3e-28 97.5 7.7 6.3e-06 26.8 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 EEQ28094.1 - 6.8e-06 25.9 0.1 1.4e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like PQQ PF01011.21 EEQ28094.1 - 1.8e-05 24.4 0.1 1.4 9.0 0.0 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 EEQ28094.1 - 3.6e-05 23.5 0.1 0.063 12.9 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain ANAPC4_WD40 PF12894.7 EEQ28094.1 - 0.0013 18.9 0.8 8.2 6.8 0.0 4.7 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain STE PF02200.16 EEQ28094.1 - 0.043 14.2 0.1 0.84 10.1 0.0 2.4 2 0 0 2 2 2 0 STE like transcription factor PQQ_3 PF13570.6 EEQ28094.1 - 1.1 9.9 2.8 98 3.6 0.0 4.3 4 1 1 5 5 5 0 PQQ-like domain ADH_zinc_N_2 PF13602.6 EEQ28095.1 - 3e-13 51.0 0.0 5.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EEQ28095.1 - 4e-07 30.1 0.0 9.9e-07 28.8 0.0 1.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase EB1 PF03271.17 EEQ28097.1 - 3.5e-17 62.3 1.7 6.6e-17 61.5 1.7 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EEQ28097.1 - 1.9e-06 28.0 0.6 5.8e-06 26.4 0.7 1.8 1 1 1 2 2 2 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 EEQ28097.1 - 0.0014 17.3 0.0 0.0019 16.8 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like CH_2 PF06294.11 EEQ28097.1 - 0.041 14.0 0.1 0.06 13.5 0.1 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein Macoilin PF09726.9 EEQ28099.1 - 0.31 9.6 6.8 0.4 9.2 6.8 1.2 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 EEQ28099.1 - 2 7.5 27.1 3.3 6.8 27.1 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Glutaredoxin PF00462.24 EEQ28102.1 - 4.6e-19 68.4 0.0 6.6e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EEQ28102.1 - 0.024 15.1 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 EEQ28102.1 - 0.086 12.8 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Chalcone_2 PF16035.5 EEQ28103.1 - 1.3e-74 250.4 0.0 1.8e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EEQ28103.1 - 0.0068 16.5 0.0 0.028 14.5 0.0 2.0 2 0 0 2 2 2 1 Chalcone isomerase-like GTP_EFTU PF00009.27 EEQ28104.1 - 4.8e-54 182.8 0.0 7.8e-54 182.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEQ28104.1 - 5.6e-42 142.6 0.0 1.3e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEQ28104.1 - 7.1e-14 51.9 1.8 2.3e-13 50.3 1.8 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ28104.1 - 0.0047 17.0 0.1 0.047 13.8 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EEQ28104.1 - 0.058 13.3 1.3 0.18 11.7 1.3 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 TFIIS_C PF01096.18 EEQ28105.1 - 3.5e-19 68.4 2.2 3.5e-19 68.4 2.2 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EEQ28105.1 - 9.1e-06 25.5 9.3 0.0002 21.1 5.3 3.4 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EEQ28105.1 - 0.0023 17.9 7.0 0.12 12.3 1.3 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zf-Mss51 PF13824.6 EEQ28105.1 - 0.023 14.8 2.5 0.22 11.6 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 C1_4 PF07975.12 EEQ28105.1 - 0.13 12.6 3.9 1.8 8.9 0.2 2.5 2 2 0 2 2 2 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.6 EEQ28105.1 - 0.24 12.0 2.6 0.67 10.5 0.5 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.12 EEQ28105.1 - 0.69 9.5 5.3 4.6 6.8 0.1 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding Rubredoxin PF00301.20 EEQ28105.1 - 0.92 9.6 7.9 8.6 6.5 0.2 3.4 3 0 0 3 3 3 0 Rubredoxin zinc_ribbon_4 PF13717.6 EEQ28105.1 - 2.5 8.1 12.7 4.8 7.2 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 EEQ28105.1 - 4.7 7.8 12.1 3.9 8.1 0.3 3.5 4 0 0 4 4 4 0 Zinc-finger double domain NAD_binding_10 PF13460.6 EEQ28106.1 - 9.8e-06 25.6 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ28106.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 EEQ28106.1 - 0.037 14.1 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EEQ28106.1 - 0.075 13.6 0.0 2 9.0 0.0 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 EEQ28106.1 - 0.09 12.2 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 EEQ28107.1 - 8.6e-93 311.2 0.0 1.7e-92 310.2 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EEQ28107.1 - 1.1e-76 257.8 0.1 1.8e-75 253.8 0.1 2.4 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EEQ28107.1 - 1.3e-60 205.6 0.1 2.3e-60 204.8 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EEQ28107.1 - 7.1e-55 185.7 0.0 2.3e-54 184.0 0.1 2.0 2 0 0 2 2 1 1 KR domain NAD_binding_4 PF07993.12 EEQ28107.1 - 1e-44 152.7 0.0 2.1e-43 148.4 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EEQ28107.1 - 1.7e-39 134.5 0.3 4e-39 133.3 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EEQ28107.1 - 3.3e-20 72.2 1.9 9.5e-12 45.1 0.0 3.9 4 0 0 4 4 4 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EEQ28107.1 - 1.6e-11 44.7 0.0 3.6e-10 40.3 0.0 2.9 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EEQ28107.1 - 2.2e-11 43.7 0.0 1.7e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EEQ28107.1 - 8.9e-07 29.8 0.0 3.9e-06 27.8 0.0 2.2 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 EEQ28107.1 - 4.1e-06 26.4 0.0 2.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EEQ28107.1 - 1.9e-05 24.2 0.0 0.0048 16.3 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EEQ28107.1 - 2.8e-05 23.4 0.0 0.013 14.7 0.0 2.7 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 EEQ28107.1 - 4.2e-05 23.0 0.1 8.2e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 EEQ28107.1 - 0.00057 19.0 0.0 0.11 11.5 0.0 2.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family ACP_syn_III PF08545.10 EEQ28107.1 - 0.015 15.1 1.4 0.048 13.5 1.4 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NmrA PF05368.13 EEQ28107.1 - 0.038 13.5 0.2 2.2 7.7 0.0 2.6 2 0 0 2 2 2 0 NmrA-like family PhyH PF05721.13 EEQ28108.1 - 1.7e-16 61.1 0.0 2.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_1_2 PF00155.21 EEQ28109.1 - 2e-18 66.7 0.0 2.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ28109.1 - 0.0087 15.1 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V NmrA PF05368.13 EEQ28110.1 - 1.2e-13 51.2 0.0 1.8e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EEQ28110.1 - 1.8e-12 47.5 0.1 3.5e-12 46.6 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EEQ28110.1 - 8.2e-06 25.9 0.3 1.2e-05 25.3 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ28110.1 - 0.0001 21.9 0.0 0.00028 20.4 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EEQ28110.1 - 0.002 18.4 0.4 0.0037 17.5 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain CbiJ PF02571.14 EEQ28110.1 - 0.0079 15.7 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK adh_short PF00106.25 EEQ28110.1 - 0.047 13.1 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF5022 PF16425.5 EEQ28110.1 - 0.1 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5022) RmlD_sub_bind PF04321.17 EEQ28110.1 - 0.1 11.7 0.4 0.16 11.0 0.4 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain AA_permease_2 PF13520.6 EEQ28111.1 - 1.1e-35 123.4 50.5 1.3e-35 123.1 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ28111.1 - 0.00029 19.5 45.4 0.00051 18.8 45.4 1.3 1 1 0 1 1 1 1 Amino acid permease PhyH PF05721.13 EEQ28112.1 - 3e-22 79.9 0.0 3.8e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EEQ28112.1 - 0.046 12.5 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Ank PF00023.30 EEQ28113.1 - 1.2e-08 35.0 0.2 0.00016 22.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EEQ28113.1 - 9.6e-08 31.7 0.2 0.00038 20.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EEQ28113.1 - 3.9e-07 30.5 0.0 0.018 15.6 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ28113.1 - 2.8e-05 24.3 0.3 1.5 9.3 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ28113.1 - 5e-05 23.8 0.0 0.0014 19.2 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) MAGE PF01454.19 EEQ28114.1 - 5.3e-63 212.6 0.0 8.3e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 MAGE family DUF1147 PF06615.11 EEQ28114.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) APH PF01636.23 EEQ28115.1 - 1.6e-12 47.9 0.0 9.5e-12 45.3 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ28115.1 - 0.14 11.0 0.0 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) ATPgrasp_N PF18130.1 EEQ28116.1 - 5e-19 68.6 0.1 2e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EEQ28116.1 - 7.4e-11 41.9 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EEQ28116.1 - 9.8e-07 28.5 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EEQ28116.1 - 0.00014 21.4 0.0 0.00038 20.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EEQ28116.1 - 0.00025 21.1 0.0 0.00081 19.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EEQ28116.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pal1 PF08316.11 EEQ28117.1 - 3.3e-47 160.7 0.9 7.4e-47 159.6 0.9 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein CAP_N PF01213.19 EEQ28117.1 - 0.56 9.6 3.0 1.2 8.5 3.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Med31 PF05669.12 EEQ28119.1 - 1e-27 95.9 0.3 2.7e-27 94.6 0.3 1.7 1 0 0 1 1 1 1 SOH1 PHD PF00628.29 EEQ28121.1 - 5.9e-10 38.9 8.0 5.9e-10 38.9 8.0 2.2 2 0 0 2 2 2 1 PHD-finger Choline_kinase PF01633.20 EEQ28121.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fungal_trans PF04082.18 EEQ28123.1 - 4.8e-29 101.2 0.0 8.2e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ28123.1 - 6.1e-11 42.3 13.4 1.3e-10 41.2 13.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EEQ28123.1 - 0.2 11.9 0.1 0.67 10.2 0.1 1.9 1 0 0 1 1 1 0 Gal4-like dimerisation domain zf-C2H2 PF00096.26 EEQ28124.1 - 9.9e-06 25.7 19.6 4.3e-05 23.7 2.8 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ28124.1 - 3.4e-05 24.1 3.3 3.4e-05 24.1 3.3 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ28124.1 - 0.00014 22.4 1.7 0.00014 22.4 1.7 3.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ28124.1 - 0.0013 18.9 0.7 0.0048 17.1 0.7 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EEQ28124.1 - 0.0037 17.2 1.3 0.01 15.8 1.3 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EEQ28124.1 - 0.02 15.2 3.7 0.02 15.2 3.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon Forkhead PF00250.18 EEQ28125.1 - 8e-34 115.8 1.6 1.6e-33 114.8 1.6 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EEQ28125.1 - 2.9e-08 33.9 0.0 2.6e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 FHA domain Linker_histone PF00538.19 EEQ28125.1 - 0.013 15.9 0.2 0.027 14.8 0.2 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family TFIIF_beta_N PF17683.1 EEQ28126.1 - 0.16 12.6 2.5 1.3 9.7 0.2 2.5 2 0 0 2 2 2 0 TFIIF, beta subunit N-terminus Lsr2 PF11774.8 EEQ28126.1 - 4.3 7.5 8.8 1.8 8.8 0.8 2.9 3 0 0 3 3 3 0 Lsr2 Ribosomal_L24e PF01246.20 EEQ28128.1 - 6.3e-30 103.2 4.5 1.7e-29 101.8 4.5 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e DUF4820 PF16091.5 EEQ28128.1 - 0.037 13.4 3.9 0.05 13.0 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4192 PF13830.6 EEQ28128.1 - 0.062 13.4 1.1 0.068 13.2 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Pam16 PF03656.13 EEQ28129.1 - 2.3e-06 27.6 0.2 5e-06 26.5 0.2 1.6 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 EEQ28129.1 - 0.0001 22.4 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 EEQ28129.1 - 0.0017 17.9 0.9 0.0017 17.9 0.9 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) Pkinase PF00069.25 EEQ28130.1 - 1.3e-65 221.4 0.0 1.7e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28130.1 - 8.8e-31 107.1 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ28130.1 - 0.011 14.8 0.0 0.027 13.4 0.0 1.8 2 1 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 EEQ28130.1 - 0.051 12.9 0.1 0.11 11.8 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ28130.1 - 0.13 12.2 4.6 0.17 11.8 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family G_glu_transpept PF01019.21 EEQ28131.1 - 1.9e-133 445.9 0.0 2.2e-133 445.7 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HHH_3 PF12836.7 EEQ28131.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif p450 PF00067.22 EEQ28132.1 - 2.3e-25 89.3 0.0 3.7e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF333 PF03891.15 EEQ28134.1 - 0.13 12.5 0.0 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF333) ICL PF00463.21 EEQ28135.1 - 1.4e-299 994.0 0.9 1.6e-299 993.8 0.9 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EEQ28135.1 - 1.6e-11 44.1 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.18 EEQ28137.1 - 8e-196 651.8 0.0 9.5e-196 651.6 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EEQ28137.1 - 7.5e-17 60.8 0.1 1.2e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF4024 PF13216.6 EEQ28137.1 - 0.067 13.1 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) adh_short_C2 PF13561.6 EEQ28138.1 - 2.5e-49 168.0 0.0 2.9e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ28138.1 - 9.2e-46 155.8 0.0 1.1e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ28138.1 - 1.1e-06 28.6 0.0 2.7e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 KR domain OTU PF02338.19 EEQ28139.1 - 4.6e-20 72.4 0.0 1.3e-19 70.9 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EEQ28139.1 - 2.3e-05 24.0 0.1 0.019 14.4 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain DUF4407 PF14362.6 EEQ28139.1 - 0.0037 16.7 7.8 0.0066 15.8 7.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Nairovirus_M PF07948.11 EEQ28139.1 - 0.13 10.5 0.2 0.17 10.1 0.2 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Cep57_MT_bd PF06657.13 EEQ28139.1 - 0.24 11.9 5.0 0.57 10.7 5.0 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4551 PF15087.6 EEQ28139.1 - 0.68 8.7 5.7 0.96 8.2 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Golgin_A5 PF09787.9 EEQ28139.1 - 1 8.8 8.8 1.4 8.3 2.8 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spore_III_AF PF09581.10 EEQ28139.1 - 1.4 8.9 4.9 3.4 7.6 4.9 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TPMT PF05724.11 EEQ28140.1 - 2e-26 93.0 0.0 9.9e-26 90.7 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 EEQ28140.1 - 8.7e-05 22.3 0.0 0.00022 21.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ28140.1 - 9.5e-05 23.0 0.0 0.00018 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ28140.1 - 0.00021 21.9 0.0 0.00034 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 EEQ28140.1 - 0.017 14.4 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Methyltransf_23 PF13489.6 EEQ28140.1 - 0.039 13.8 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 EEQ28140.1 - 0.1 13.0 0.1 0.23 11.8 0.1 1.5 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MFS_1 PF07690.16 EEQ28141.1 - 3.3e-50 171.0 67.3 2.2e-43 148.5 40.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ28141.1 - 5.3e-08 32.2 13.6 5.3e-08 32.2 13.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter BNR_4 PF15892.5 EEQ28142.1 - 0.084 12.2 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-containing family member Pkinase PF00069.25 EEQ28143.1 - 5e-20 72.0 0.0 3.4e-19 69.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28143.1 - 0.0048 16.2 0.0 0.031 13.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Ephrin PF00812.17 EEQ28144.1 - 0.019 14.9 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Ephrin Aldedh PF00171.22 EEQ28147.1 - 3.8e-84 282.9 0.0 4.6e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adap_comp_sub PF00928.21 EEQ28148.1 - 2.1e-59 201.1 0.0 2.6e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EEQ28148.1 - 0.00058 19.8 0.0 0.00095 19.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4588 PF15251.6 EEQ28149.1 - 0.00011 22.1 0.9 0.00011 22.1 0.9 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4588) SNF2_N PF00176.23 EEQ28150.1 - 8.3e-75 251.7 0.1 1.6e-74 250.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EEQ28150.1 - 2.6e-43 146.7 0.9 2.6e-43 146.7 0.9 2.6 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 EEQ28150.1 - 4.2e-30 104.7 5.1 4.2e-30 104.7 5.1 4.5 5 0 0 5 5 5 1 HAND Helicase_C PF00271.31 EEQ28150.1 - 5.9e-18 65.2 0.5 3.1e-17 62.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ28150.1 - 5e-11 42.9 0.1 6.6e-10 39.3 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EEQ28150.1 - 4e-06 26.2 0.1 2.1e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EEQ28150.1 - 0.00048 19.9 0.0 0.0015 18.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 EEQ28150.1 - 0.00083 19.5 0.0 2.2 8.6 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF1086 PF06461.11 EEQ28150.1 - 0.00092 19.1 0.1 0.0028 17.5 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) AAA_14 PF13173.6 EEQ28150.1 - 0.031 14.3 0.0 0.14 12.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 EEQ28150.1 - 0.035 13.7 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 Occludin_ELL PF07303.13 EEQ28150.1 - 0.15 12.8 4.5 0.82 10.4 4.5 2.3 1 0 0 1 1 1 0 Occludin homology domain ING PF12998.7 EEQ28150.1 - 4.1 8.1 6.9 18 6.0 0.2 4.4 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding SpoU_methylase PF00588.19 EEQ28151.1 - 1.8e-23 83.3 0.0 3.8e-23 82.2 0.0 1.5 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EEQ28151.1 - 5.6e-05 23.3 0.0 0.00015 22.0 0.0 1.8 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.6 EEQ28152.1 - 8.9e-62 207.7 11.0 2e-61 206.5 11.0 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 EEQ28152.1 - 2.4e-30 105.5 3.1 2.9e-15 55.8 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 EEQ28152.1 - 2.5e-25 88.1 2.4 3.3e-25 87.7 0.6 2.2 2 0 0 2 2 2 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 EEQ28152.1 - 6.8e-19 68.3 0.0 2.2e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EEQ28152.1 - 3.9e-07 29.5 1.9 1.3e-06 27.8 1.9 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 EEQ28152.1 - 1.7e-06 27.9 2.8 0.0098 15.8 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 EEQ28152.1 - 7.1e-06 25.8 17.6 1.8e-05 24.5 3.3 3.7 2 1 0 2 2 2 1 PHD-finger DUF1087 PF06465.13 EEQ28152.1 - 0.00018 21.5 0.8 0.00047 20.1 0.3 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) SnAC PF14619.6 EEQ28152.1 - 0.012 16.3 0.3 0.083 13.5 0.3 2.5 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 EEQ28152.1 - 0.033 14.2 0.0 0.2 11.6 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1629 PF07791.11 EEQ28153.1 - 0.088 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) zf-CCCH PF00642.24 EEQ28153.1 - 0.13 12.2 0.7 0.26 11.2 0.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MRP-S28 PF10213.9 EEQ28154.1 - 3.2e-40 137.5 0.0 5.8e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF4702 PF15774.5 EEQ28154.1 - 0.024 13.6 1.4 0.04 12.9 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) Glyco_tran_28_C PF04101.16 EEQ28155.1 - 2.9e-18 66.4 0.2 2.2e-17 63.5 0.2 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Actin PF00022.19 EEQ28156.1 - 1.6e-125 418.9 0.0 6.9e-125 416.9 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEQ28156.1 - 0.14 10.9 0.0 6.2 5.5 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein DUF3602 PF12223.8 EEQ28157.1 - 1.3e-19 70.6 2.3 4.1e-14 52.9 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 EEQ28157.1 - 0.12 12.0 4.3 12 5.5 0.2 3.0 1 1 2 3 3 3 0 GTP1/OBG HsbA PF12296.8 EEQ28160.1 - 8.6e-11 42.3 0.0 1.2e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A p450 PF00067.22 EEQ28161.1 - 3.9e-54 184.1 0.0 4.9e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRP PF06011.12 EEQ28163.1 - 6.3e-146 486.4 32.3 4.7e-78 262.8 13.7 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EEQ28163.1 - 6.3e-36 123.8 0.1 1.1e-35 123.1 0.1 1.4 1 0 0 1 1 1 1 ML-like domain APH PF01636.23 EEQ28167.1 - 2.2e-13 50.7 0.0 5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EEQ28167.1 - 0.0068 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EEQ28167.1 - 0.024 14.2 0.1 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EEQ28167.1 - 0.06 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) HAD_2 PF13419.6 EEQ28168.1 - 1.3e-15 57.9 0.0 1.6e-14 54.4 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ28168.1 - 2.4e-14 54.1 0.0 3.7e-13 50.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ28168.1 - 1.2e-06 28.4 0.1 2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EEQ28168.1 - 0.00036 21.0 0.0 0.00061 20.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EEQ28168.1 - 0.048 13.8 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF908 PF06012.12 EEQ28169.1 - 0.38 10.1 2.6 0.62 9.4 2.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ORMDL PF04061.14 EEQ28170.1 - 1.8e-58 196.2 3.4 2.1e-58 196.0 3.4 1.0 1 0 0 1 1 1 1 ORMDL family PGA2 PF07543.12 EEQ28171.1 - 0.0065 16.5 3.2 0.034 14.1 2.5 2.1 2 0 0 2 2 2 1 Protein trafficking PGA2 CH PF00307.31 EEQ28172.1 - 3.9e-12 46.3 0.0 6.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EEQ28172.1 - 0.2 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Calponin PF00402.18 EEQ28172.1 - 0.26 11.0 6.0 1.1 8.9 1.3 2.7 2 0 0 2 2 2 0 Calponin family repeat NDUFA12 PF05071.16 EEQ28173.1 - 1.8e-10 41.5 6.8 1.2e-09 38.9 6.8 2.2 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 SDA1 PF05285.12 EEQ28175.1 - 0.11 11.9 16.0 0.14 11.5 16.0 1.2 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 EEQ28175.1 - 0.19 10.9 1.2 0.25 10.5 1.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PPP4R2 PF09184.11 EEQ28175.1 - 0.42 10.2 13.9 0.65 9.5 13.9 1.3 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 EEQ28175.1 - 0.5 10.1 15.5 0.91 9.2 15.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.14 EEQ28175.1 - 1.9 8.2 9.1 3.6 7.3 9.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.10 EEQ28175.1 - 3.4 6.9 14.2 4.5 6.5 14.2 1.3 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EEQ28175.1 - 4.2 5.4 23.2 7.6 4.5 23.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi EMP24_GP25L PF01105.24 EEQ28179.1 - 3.1e-39 134.8 0.0 3.4e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4665 PF15679.5 EEQ28179.1 - 0.027 15.1 0.1 0.046 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) EzrA PF06160.12 EEQ28179.1 - 0.052 11.7 0.2 0.068 11.3 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sdh5 PF03937.16 EEQ28180.1 - 3.3e-24 84.6 0.2 9.3e-24 83.2 0.2 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase WD40 PF00400.32 EEQ28181.1 - 7.9e-45 150.0 27.0 1.2e-09 38.7 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ28181.1 - 9.6e-10 38.6 0.6 0.06 13.7 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ28181.1 - 2.8e-05 23.0 8.3 0.084 11.5 0.2 4.8 1 1 4 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ28181.1 - 0.0016 17.5 0.0 0.73 8.7 0.0 3.7 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EEQ28181.1 - 0.015 15.3 0.1 20 5.3 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EEQ28181.1 - 0.017 13.7 0.0 1.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 EEQ28181.1 - 0.028 13.7 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain TPR_1 PF00515.28 EEQ28182.1 - 9.5e-06 25.2 6.5 0.16 11.9 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ28182.1 - 2.3e-05 24.6 11.0 0.5 10.7 0.2 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ28182.1 - 0.00042 20.2 9.6 0.17 12.1 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ28182.1 - 0.032 14.4 8.9 5.6 7.4 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ28182.1 - 0.068 13.2 12.1 3.8 7.7 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF627 PF04781.12 EEQ28182.1 - 0.08 13.0 0.8 0.26 11.3 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_19 PF14559.6 EEQ28182.1 - 0.17 12.4 3.3 0.38 11.3 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 EEQ28182.1 - 0.33 11.7 3.0 24 5.8 0.1 3.9 4 0 0 4 4 4 0 Sel1 repeat TPR_6 PF13174.6 EEQ28182.1 - 0.5 11.1 8.6 1.1e+02 3.8 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat SRAP PF02586.14 EEQ28183.1 - 8.6e-80 267.4 0.0 1.1e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) MAAL_C PF07476.11 EEQ28183.1 - 0.091 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Med1 PF10744.9 EEQ28185.1 - 2.6e-129 431.9 0.0 3.4e-129 431.5 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Gln-synt_C PF00120.24 EEQ28186.1 - 8.2e-16 57.9 0.0 9.4e-13 47.9 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EEQ28186.1 - 4.7e-12 45.5 0.0 8.2e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.16 EEQ28187.1 - 2.4e-28 99.1 39.0 2.4e-28 99.1 39.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EEQ28187.1 - 0.0078 15.9 3.8 0.019 14.7 3.8 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 AMP-binding PF00501.28 EEQ28188.1 - 6e-46 156.9 0.0 2.8e-45 154.7 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ28188.1 - 0.12 13.4 0.0 0.43 11.6 0.0 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.24 EEQ28189.1 - 1.3e-104 350.6 21.6 1.7e-104 350.3 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ28189.1 - 3.8e-17 62.3 37.8 7.3e-14 51.5 8.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily zf-CCHC PF00098.23 EEQ28190.1 - 8.9e-49 161.5 93.2 9.3e-08 31.8 2.7 12.2 12 0 0 12 12 12 10 Zinc knuckle zf-CCHC_4 PF14392.6 EEQ28190.1 - 3.4e-09 36.3 56.4 0.2 11.4 0.4 10.3 10 0 0 10 10 10 9 Zinc knuckle zf-CCHC_2 PF13696.6 EEQ28190.1 - 7.8e-09 35.2 81.6 0.00039 20.2 0.7 11.3 12 0 0 12 12 12 6 Zinc knuckle zf-CCHC_3 PF13917.6 EEQ28190.1 - 1.6e-05 24.8 71.9 0.046 13.7 0.9 9.8 3 2 6 9 9 9 7 Zinc knuckle zf-CCCH_8 PF18633.1 EEQ28190.1 - 0.0018 18.3 2.0 0.0082 16.2 2.0 2.2 1 0 0 1 1 1 1 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 Elf1 PF05129.13 EEQ28190.1 - 0.011 15.8 2.3 0.011 15.8 2.3 5.0 4 2 2 6 6 6 0 Transcription elongation factor Elf1 like RNA_POL_M_15KD PF02150.16 EEQ28191.1 - 0.17 11.8 2.7 0.45 10.4 0.2 2.6 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Pkinase PF00069.25 EEQ28192.1 - 4.1e-27 95.2 0.0 4.8e-26 91.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28192.1 - 0.00019 20.8 0.0 0.059 12.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EEQ28192.1 - 0.27 10.1 0.4 0.39 9.6 0.4 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF846 PF05832.12 EEQ28194.1 - 5.3e-43 146.4 7.4 6.2e-43 146.2 7.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Acyl-CoA_dh_1 PF00441.24 EEQ28195.1 - 4.6e-31 108.1 0.1 6.2e-31 107.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EEQ28195.1 - 3.3e-23 81.7 0.0 1.2e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EEQ28195.1 - 2e-22 80.0 0.0 5.4e-21 75.4 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EEQ28195.1 - 0.00018 21.8 0.0 0.00026 21.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 EEQ28196.1 - 3.3e-36 124.9 0.0 2.2e-31 109.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EEQ28196.1 - 1.1e-13 51.4 1.0 2.7e-09 37.0 0.0 3.0 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase HpcH_HpaI PF03328.14 EEQ28197.1 - 1.9e-43 148.2 0.0 1.4e-42 145.3 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EEQ28197.1 - 6.5e-14 51.8 0.0 1.9e-06 27.3 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Smr PF01713.21 EEQ28198.1 - 1.2e-10 41.6 0.0 3.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 EEQ28198.1 - 7.3e-08 32.2 10.1 1.5e-06 28.0 0.6 3.2 2 1 0 2 2 2 2 Zinc finger domain DUF1771 PF08590.10 EEQ28198.1 - 1.4e-07 31.8 4.3 1.9e-07 31.3 2.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.24 EEQ28198.1 - 1.3e-06 28.1 2.3 0.013 15.4 0.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EEQ28198.1 - 1.1e-05 25.1 10.5 0.00039 20.2 0.5 3.0 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EEQ28198.1 - 0.0011 19.3 5.7 0.24 11.9 0.7 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EEQ28198.1 - 0.0012 19.1 2.9 0.99 9.7 0.1 2.5 1 1 1 2 2 2 2 Zinc-finger containing family HBS1_N PF08938.10 EEQ28198.1 - 0.079 13.3 0.2 0.54 10.6 0.0 2.3 2 0 0 2 2 2 0 HBS1 N-terminus Glyco_transf_90 PF05686.12 EEQ28199.1 - 2.4e-13 49.8 3.9 2.7e-11 43.0 2.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 CAP59_mtransfer PF11735.8 EEQ28200.1 - 5.3e-83 278.4 0.0 6.7e-83 278.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 LTP_2 PF14368.6 EEQ28201.1 - 0.007 16.4 3.4 0.007 16.4 3.4 1.4 1 1 0 1 1 1 1 Probable lipid transfer DUF346 PF03984.13 EEQ28202.1 - 2.2e-62 206.5 64.5 1.1e-10 41.1 3.5 7.2 7 0 0 7 7 7 7 Repeat of unknown function (DUF346) Ntox14 PF15522.6 EEQ28202.1 - 0.00019 20.9 0.0 41 3.5 0.0 5.7 7 0 0 7 7 7 0 Novel toxin 14 DUF2510 PF10708.9 EEQ28202.1 - 0.014 15.1 48.9 0.13 12.0 3.0 6.4 6 0 0 6 6 6 0 Protein of unknown function (DUF2510) DUF1724 PF08350.10 EEQ28202.1 - 0.025 14.7 5.9 4.4 7.5 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF1724) DUF3622 PF12286.8 EEQ28202.1 - 0.034 14.5 0.0 16 6.0 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3622) Pkinase PF00069.25 EEQ28203.1 - 2.2e-13 50.2 0.0 2.9e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain SNARE_assoc PF09335.11 EEQ28204.1 - 1.8e-06 28.4 9.0 1.8e-06 28.4 9.0 3.4 2 1 1 3 3 3 1 SNARE associated Golgi protein Amino_oxidase PF01593.24 EEQ28205.1 - 7.6e-85 285.9 0.0 3.5e-73 247.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 EEQ28205.1 - 3e-13 49.9 0.2 1e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 EEQ28205.1 - 5.2e-08 33.0 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 EEQ28205.1 - 8.3e-06 26.1 1.4 7.7e-05 23.0 1.4 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box DAO PF01266.24 EEQ28205.1 - 0.00064 19.4 0.2 0.0015 18.2 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ28205.1 - 0.0012 18.1 0.0 0.045 13.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ28205.1 - 0.012 15.6 0.3 1.7 8.6 0.0 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding TPR_11 PF13414.6 EEQ28205.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 TPR repeat HMG_box_2 PF09011.10 EEQ28205.1 - 0.38 11.4 1.9 0.76 10.4 0.9 2.0 2 0 0 2 2 2 0 HMG-box domain DUF737 PF05300.11 EEQ28205.1 - 2.2 8.6 5.1 0.23 11.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Pyr_redox_2 PF07992.14 EEQ28206.1 - 5.1e-51 173.6 0.3 6.1e-51 173.4 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ28206.1 - 8.7e-18 64.6 0.1 4.7e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ28206.1 - 5.3e-16 58.9 0.7 3.9e-13 49.8 0.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEQ28206.1 - 2.8e-05 23.5 0.5 6.5e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 EEQ28206.1 - 0.00011 22.6 0.1 0.015 15.7 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EEQ28206.1 - 0.00017 21.7 0.1 0.15 12.3 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EEQ28206.1 - 0.0026 16.9 0.0 0.34 10.0 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EEQ28206.1 - 0.011 15.0 0.4 2.2 7.5 0.0 2.6 2 1 0 2 2 2 0 FAD binding domain DAO PF01266.24 EEQ28206.1 - 0.021 14.4 2.2 13 5.2 0.0 3.6 2 2 1 4 4 4 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EEQ28206.1 - 0.025 13.7 4.2 0.37 9.8 0.4 2.8 2 1 1 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 EEQ28206.1 - 0.1 11.9 0.9 0.28 10.5 0.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EEQ28206.1 - 0.13 11.3 7.6 2.7 7.0 0.3 3.9 3 1 0 4 4 4 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 EEQ28206.1 - 0.16 12.0 0.2 8.5 6.4 0.0 2.7 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase LEA_1 PF03760.15 EEQ28207.1 - 3.6 8.3 5.7 10 6.8 5.7 1.8 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Pkinase PF00069.25 EEQ28209.1 - 2.8e-25 89.2 0.0 3.3e-24 85.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28209.1 - 5.2e-16 58.7 0.2 4.2e-07 29.5 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ28209.1 - 0.0039 16.0 0.1 0.23 10.2 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase FTA2 PF13095.6 EEQ28209.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEQ28210.1 - 1.5e-10 41.4 0.0 2.5e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ28210.1 - 4e-09 36.4 0.2 2.2e-08 34.0 0.2 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ28210.1 - 1.2e-05 24.8 0.0 0.0041 16.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.11 EEQ28210.1 - 0.12 11.2 0.1 0.3 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Sulfotransfer_4 PF17784.1 EEQ28211.1 - 2.4e-63 213.9 0.1 2.8e-63 213.6 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EEQ28211.1 - 0.0059 17.0 0.8 0.088 13.2 0.2 2.2 1 1 1 2 2 2 1 Sulfotransferase family DUF2116 PF09889.9 EEQ28211.1 - 0.031 14.3 0.1 0.056 13.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Peptidase_S8 PF00082.22 EEQ28212.1 - 4.9e-32 111.4 1.4 7.3e-32 110.8 1.4 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EEQ28212.1 - 4.4e-29 100.3 0.4 9.7e-29 99.2 0.4 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Metallophos PF00149.28 EEQ28213.1 - 5.8e-08 33.5 1.3 1e-05 26.1 1.3 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEQ28213.1 - 9.4e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PX PF00787.24 EEQ28214.1 - 1.3e-18 67.0 0.5 3.2e-18 65.8 0.5 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EEQ28214.1 - 1.7e-12 47.4 9.5 1.1e-06 28.4 0.6 2.1 1 1 0 2 2 2 2 Vps5 C terminal like Occludin_ELL PF07303.13 EEQ28214.1 - 0.0073 17.0 0.5 0.53 11.0 0.0 2.9 2 0 0 2 2 2 1 Occludin homology domain DUF1664 PF07889.12 EEQ28214.1 - 0.028 14.5 0.6 2.7 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BAR PF03114.18 EEQ28214.1 - 0.37 10.4 8.6 2 8.0 5.3 2.5 2 1 0 2 2 2 0 BAR domain DASH_Dad3 PF08656.10 EEQ28214.1 - 0.6 10.2 3.9 1.2 9.2 0.1 2.9 1 1 1 2 2 2 0 DASH complex subunit Dad3 FlaC_arch PF05377.11 EEQ28214.1 - 5.5 7.5 5.7 17 5.9 0.9 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FAD_binding_3 PF01494.19 EEQ28215.1 - 2.3e-21 76.5 0.0 7.5e-11 41.9 0.0 2.4 1 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EEQ28215.1 - 0.0016 17.5 0.1 0.0046 16.1 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein SE PF08491.10 EEQ28215.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 EEQ28215.1 - 0.0055 16.9 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EEQ28215.1 - 0.006 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EEQ28215.1 - 0.01 15.1 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ28215.1 - 0.026 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EEQ28215.1 - 0.092 11.6 0.1 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 EEQ28215.1 - 0.094 12.3 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EEQ28215.1 - 0.19 11.0 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family tRNA-synt_His PF13393.6 EEQ28216.1 - 4e-35 121.6 0.0 6.5e-29 101.2 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EEQ28216.1 - 8.8e-13 48.2 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EEQ28216.1 - 3.7e-05 23.8 0.0 7.2e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 EEQ28216.1 - 0.0063 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 EEQ28216.1 - 0.039 13.0 0.0 0.1 11.7 0.0 1.7 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) dUTPase PF00692.19 EEQ28217.1 - 1.3e-09 37.8 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 dUTPase DDE_Tnp_2 PF04693.12 EEQ28217.1 - 0.098 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 UCH PF00443.29 EEQ28218.1 - 1.1e-45 156.2 0.3 1.1e-45 156.2 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ28218.1 - 1.6e-20 73.9 0.2 3.1e-20 73.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1682 PF07946.14 EEQ28218.1 - 0.84 8.8 14.6 2.3 7.4 14.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Nop53 PF07767.11 EEQ28218.1 - 1.6 8.1 28.1 4.5 6.6 28.1 1.8 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Peptidase_C98 PF15499.6 EEQ28218.1 - 2.4 7.6 14.0 0.045 13.2 2.5 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Presenilin PF01080.17 EEQ28218.1 - 4.2 6.0 9.3 9.6 4.8 9.3 1.5 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 EEQ28218.1 - 7.7 4.9 22.8 14 4.0 22.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Yos1 PF08571.10 EEQ28219.1 - 2.5e-08 34.1 0.0 3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Yos1-like UL20 PF17582.2 EEQ28219.1 - 0.0031 16.9 0.0 0.0031 16.9 0.0 1.0 1 0 0 1 1 1 1 Cytomegalovirus UL20 HNH_2 PF13391.6 EEQ28220.1 - 2.4e-08 34.0 0.0 5.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.25 EEQ28221.1 - 1.8e-14 53.8 0.0 2.3e-06 27.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28221.1 - 0.0052 16.1 0.0 1.9 7.7 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Glyco_transf_22 PF03901.17 EEQ28222.1 - 3.8e-35 121.9 20.3 4.8e-35 121.6 20.3 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamitin PF04912.14 EEQ28223.1 - 5.8e-74 249.8 8.0 5.6e-38 131.3 1.2 2.1 2 0 0 2 2 2 2 Dynamitin SOGA PF11365.8 EEQ28223.1 - 0.0002 22.4 4.7 0.06 14.5 0.5 3.3 3 0 0 3 3 3 1 Protein SOGA Jnk-SapK_ap_N PF09744.9 EEQ28223.1 - 0.00028 21.1 9.4 0.033 14.4 0.3 3.1 3 0 0 3 3 3 2 JNK_SAPK-associated protein-1 APG6_N PF17675.1 EEQ28223.1 - 0.0009 19.8 10.8 0.24 11.9 1.0 3.4 3 0 0 3 3 3 2 Apg6 coiled-coil region DUF2408 PF10303.9 EEQ28223.1 - 0.001 19.6 4.2 1.2 9.7 0.3 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF2408) SlyX PF04102.12 EEQ28223.1 - 0.0086 16.7 10.3 0.09 13.4 0.6 4.1 4 0 0 4 4 4 1 SlyX DivIC PF04977.15 EEQ28223.1 - 0.01 15.6 14.3 1.3 8.8 1.3 3.5 3 0 0 3 3 3 0 Septum formation initiator DUF812 PF05667.11 EEQ28223.1 - 0.018 13.9 6.3 0.013 14.5 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 EEQ28223.1 - 0.021 14.9 1.1 0.021 14.9 1.1 3.7 4 1 0 4 4 3 0 TPR/MLP1/MLP2-like protein Muted PF14942.6 EEQ28223.1 - 0.033 14.5 8.7 5.6 7.3 0.3 3.3 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein GAS PF13851.6 EEQ28223.1 - 0.071 12.4 8.3 0.64 9.3 1.7 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 EEQ28223.1 - 0.075 13.4 13.4 0.16 12.3 1.9 3.6 3 1 0 3 3 3 0 Csm1 N-terminal domain DUF16 PF01519.16 EEQ28223.1 - 0.078 13.5 3.8 0.23 12.0 0.7 2.9 3 1 0 3 3 3 0 Protein of unknown function DUF16 DUF4407 PF14362.6 EEQ28223.1 - 0.096 12.0 13.3 0.75 9.1 6.7 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EEQ28223.1 - 0.1 11.4 9.6 0.38 9.6 0.9 2.9 3 0 0 3 3 3 0 Spc7 kinetochore protein DNA_pol3_tau_4 PF12168.8 EEQ28223.1 - 0.19 12.3 0.1 0.19 12.3 0.1 2.2 2 0 0 2 2 1 0 DNA polymerase III subunits tau domain IV DnaB-binding Ax_dynein_light PF10211.9 EEQ28223.1 - 0.21 11.5 7.2 2.5 8.0 0.9 2.7 3 0 0 3 3 2 0 Axonemal dynein light chain DUF2203 PF09969.9 EEQ28223.1 - 0.22 12.2 7.3 1.5 9.6 0.4 3.5 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) Golgin_A5 PF09787.9 EEQ28223.1 - 0.23 10.9 5.0 1.7 8.0 0.5 2.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spc24 PF08286.11 EEQ28223.1 - 0.27 11.5 14.6 1 9.7 1.9 3.7 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 EEQ28223.1 - 0.29 11.1 10.9 1.6 8.7 0.2 3.5 3 1 1 4 4 4 0 Prefoldin subunit PRKG1_interact PF15898.5 EEQ28223.1 - 0.31 12.0 12.2 0.36 11.7 1.2 3.4 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF4254 PF14063.6 EEQ28223.1 - 0.35 10.7 3.9 0.58 10.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4254) Macoilin PF09726.9 EEQ28223.1 - 0.48 8.9 5.4 0.18 10.3 1.1 1.9 2 0 0 2 2 2 0 Macoilin family ADIP PF11559.8 EEQ28223.1 - 0.5 10.5 10.2 4.7 7.3 0.3 3.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding GrpE PF01025.19 EEQ28223.1 - 0.65 9.6 6.2 1.8 8.2 0.3 3.0 3 0 0 3 3 3 0 GrpE BLOC1_2 PF10046.9 EEQ28223.1 - 0.7 10.2 5.6 3.7 7.9 0.2 3.4 4 0 0 4 4 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 EEQ28223.1 - 0.74 10.3 10.7 6.1 7.4 0.6 3.7 3 1 0 3 3 3 0 Spectrin repeat KxDL PF10241.9 EEQ28223.1 - 0.87 9.9 4.1 1.9 8.8 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein DHR10 PF18595.1 EEQ28223.1 - 1.4 9.0 15.7 1 9.5 1.6 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Uso1_p115_C PF04871.13 EEQ28223.1 - 1.6 9.1 17.2 2.6 8.4 0.2 3.4 3 1 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF724 PF05266.14 EEQ28223.1 - 1.6 8.5 5.6 8.3 6.2 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Prefoldin PF02996.17 EEQ28223.1 - 1.8 8.5 12.6 2.9 7.8 1.4 3.6 4 0 0 4 4 3 0 Prefoldin subunit ZapB PF06005.12 EEQ28223.1 - 1.9 9.0 12.2 12 6.5 4.5 3.7 3 0 0 3 3 3 0 Cell division protein ZapB Rootletin PF15035.6 EEQ28223.1 - 2.1 8.3 11.0 2.4 8.1 1.8 3.1 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Fmp27_WPPW PF10359.9 EEQ28223.1 - 2.2 7.0 6.6 14 4.4 0.2 3.0 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain Cnn_1N PF07989.11 EEQ28223.1 - 2.8 8.1 10.1 14 5.9 0.9 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 EEQ28223.1 - 4.7 7.2 15.1 4.1 7.4 2.5 3.4 4 1 0 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 EEQ28223.1 - 5.3 7.2 12.1 2 8.6 5.2 3.2 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 DUF4140 PF13600.6 EEQ28223.1 - 6.4 7.3 16.4 7.5 7.1 0.1 4.1 3 2 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.12 EEQ28223.1 - 7 6.7 10.5 0.74 9.8 0.5 3.5 3 2 0 3 3 3 0 Laminin Domain II TMF_DNA_bd PF12329.8 EEQ28223.1 - 7.1 6.7 12.3 19 5.3 0.3 3.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Peptidase_M24 PF00557.24 EEQ28225.1 - 1.8e-38 132.4 0.3 2.6e-38 131.8 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDC45 PF02724.14 EEQ28225.1 - 0.27 9.5 2.1 0.36 9.1 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Aldedh PF00171.22 EEQ28226.1 - 6.5e-138 460.1 0.7 8e-138 459.8 0.7 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 EEQ28226.1 - 0.049 13.6 0.4 0.094 12.6 0.4 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family Calreticulin PF00262.18 EEQ28227.1 - 1.7e-171 570.1 16.6 1.7e-171 570.1 16.6 1.7 2 0 0 2 2 2 1 Calreticulin family DUF3149 PF11346.8 EEQ28227.1 - 3.4 7.4 4.1 6.9 6.4 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Aldolase_II PF00596.21 EEQ28228.1 - 2e-33 115.9 0.0 6.6e-32 110.9 0.0 2.1 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.10 EEQ28229.1 - 7.2e-73 245.0 7.0 7.2e-73 245.0 7.0 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EEQ28229.1 - 2.7e-25 88.5 0.2 6.5e-25 87.3 0.0 1.8 2 0 0 2 2 2 1 PX domain PilJ PF13675.6 EEQ28229.1 - 6.3 6.9 7.9 0.44 10.6 0.1 2.9 3 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3892 PF13031.6 EEQ28230.1 - 0.054 14.1 0.0 0.077 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) Tissue_fac PF01108.17 EEQ28230.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Tissue factor Flavin_Reduct PF01613.18 EEQ28231.1 - 4.6e-23 82.0 4.4 2.6e-22 79.5 4.4 2.0 1 1 0 1 1 1 1 Flavin reductase like domain APG6_N PF17675.1 EEQ28232.1 - 5.9 7.4 31.8 1.6 9.2 0.7 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region 4HBT_2 PF13279.6 EEQ28233.1 - 1.4e-05 25.6 0.0 3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily Complex1_LYR_2 PF13233.6 EEQ28234.1 - 3.8e-05 24.4 0.0 4.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EEQ28234.1 - 4.7e-05 23.4 0.2 0.0001 22.3 0.1 1.6 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Methyltransf_25 PF13649.6 EEQ28235.1 - 5.7e-11 43.0 0.0 1.1e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ28235.1 - 5.3e-08 33.4 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ28235.1 - 5.4e-05 23.0 0.0 8.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ28235.1 - 0.00035 20.0 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EEQ28235.1 - 0.00072 19.4 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ28235.1 - 0.0017 19.1 0.2 0.0038 17.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Exo_endo_phos PF03372.23 EEQ28236.1 - 5.1e-22 78.5 0.0 1.6e-21 77.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EEQ28236.1 - 1.2e-13 50.6 25.2 7.4e-07 28.8 6.5 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EEQ28236.1 - 9.1e-10 38.6 8.8 3.5e-06 27.3 1.6 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EEQ28236.1 - 0.083 13.5 2.4 4.7 8.1 0.1 3.8 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_9 PF14580.6 EEQ28236.1 - 0.12 11.9 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat TFIIA PF03153.13 EEQ28236.1 - 0.46 10.4 17.2 0.78 9.7 17.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EEQ28236.1 - 2 7.0 6.4 3 6.4 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LRR_6 PF13516.6 EEQ28236.1 - 7.1 7.0 7.3 2 8.7 0.5 3.3 4 0 0 4 4 4 0 Leucine Rich repeat MFS_1 PF07690.16 EEQ28237.1 - 3.2e-44 151.3 46.4 4.7e-44 150.7 45.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ28237.1 - 7.8e-21 74.1 17.1 5.2e-20 71.4 16.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ28237.1 - 9.3e-19 67.6 10.0 2.9e-18 66.0 0.5 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter GCD14 PF08704.10 EEQ28238.1 - 4.6e-07 29.8 0.0 0.0015 18.3 0.0 2.6 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 EEQ28238.1 - 2.9e-06 27.0 1.1 4.7e-06 26.3 0.3 1.8 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_31 PF13847.6 EEQ28238.1 - 0.052 13.4 0.0 5.9 6.7 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ28238.1 - 0.084 13.6 0.0 4.8 8.0 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.28 EEQ28239.1 - 7.4e-19 69.1 0.5 1.2e-18 68.4 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEQ28239.1 - 1.9e-06 28.1 0.1 3.6e-05 24.0 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_1 PF00175.21 EEQ28240.1 - 0.00018 22.1 0.0 0.28 11.8 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EEQ28240.1 - 0.00036 20.7 0.2 0.026 14.6 0.0 2.5 2 1 0 2 2 2 2 Ferric reductase NAD binding domain COesterase PF00135.28 EEQ28242.1 - 5.1e-58 197.2 0.0 1.8e-57 195.4 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EEQ28242.1 - 1.6e-05 24.9 0.1 7.7e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold E1-E2_ATPase PF00122.20 EEQ28244.1 - 1.3e-47 161.6 1.6 1.3e-47 161.6 1.6 2.2 3 0 0 3 3 3 1 E1-E2 ATPase HMA PF00403.26 EEQ28244.1 - 1.1e-45 153.9 0.6 2.4e-11 43.9 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EEQ28244.1 - 1e-32 114.1 0.9 2.6e-32 112.8 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEQ28244.1 - 1.4e-05 24.9 0.1 0.003 17.3 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase B12-binding PF02310.19 EEQ28244.1 - 0.011 15.8 0.1 11 6.1 0.0 4.4 5 0 0 5 5 5 0 B12 binding domain DUF1930 PF09122.10 EEQ28244.1 - 0.1 12.6 0.2 24 5.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1930) DUF2089 PF09862.9 EEQ28244.1 - 0.23 11.5 0.1 3.1 7.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) CSN7a_helixI PF18392.1 EEQ28245.1 - 0.00041 20.2 0.1 0.00088 19.1 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 EEQ28245.1 - 0.023 15.2 0.0 0.038 14.5 0.0 1.3 1 0 0 1 1 1 0 PCI domain RGS PF00615.19 EEQ28246.1 - 1.2e-12 48.1 0.0 1.1e-08 35.3 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.25 EEQ28247.1 - 1.2e-24 86.2 1.0 2.3e-24 85.3 1.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EEQ28247.1 - 2.6e-07 30.9 0.0 5.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ28247.1 - 4.3e-06 26.7 0.1 8.5e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ28247.1 - 0.0018 18.7 0.2 0.0039 17.6 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 EEQ28247.1 - 0.28 10.5 1.2 0.87 8.9 0.0 2.0 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Rad1 PF02144.16 EEQ28248.1 - 9.8e-86 287.2 0.0 1.2e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 EEQ28248.1 - 1e-06 28.9 14.9 1.6e-05 25.0 10.5 3.4 2 1 0 2 2 2 1 Oligosaccharyltransferase subunit 5 AAA_23 PF13476.6 EEQ28249.1 - 7.3e-12 46.2 13.4 1e-07 32.7 0.2 9.0 1 1 3 4 4 4 2 AAA domain SbcCD_C PF13558.6 EEQ28249.1 - 9e-07 29.1 0.0 2.6e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EEQ28249.1 - 0.00051 19.5 0.0 0.00051 19.5 0.0 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain T3SSipB PF16535.5 EEQ28249.1 - 0.0098 16.4 4.6 0.0098 16.4 4.6 8.6 3 3 4 8 8 8 2 Type III cell invasion protein SipB AAA_21 PF13304.6 EEQ28249.1 - 2.7 7.7 19.6 0.029 14.2 4.6 3.7 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system PPP4R2 PF09184.11 EEQ28250.1 - 4e-11 43.1 0.0 7.8e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 PPP4R2 DUF3480 PF11979.8 EEQ28251.1 - 0.11 11.4 0.1 1.1 8.2 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3480) zf-C2H2 PF00096.26 EEQ28252.1 - 7.8e-13 48.1 13.7 3.9e-06 27.0 2.4 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ28252.1 - 1.4e-10 41.1 9.7 3.6e-06 27.1 0.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ28252.1 - 6e-09 36.0 11.0 0.00092 19.9 1.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EEQ28252.1 - 5.8e-07 29.4 4.7 0.0022 17.9 0.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ28252.1 - 3.8e-06 27.0 0.2 0.067 13.5 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ28252.1 - 0.00017 21.8 1.3 0.013 15.8 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EEQ28252.1 - 0.00043 20.0 5.7 0.095 12.5 0.6 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 EEQ28252.1 - 0.012 16.1 1.2 0.03 14.8 1.2 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 EEQ28252.1 - 0.081 13.2 1.4 0.16 12.3 1.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EEQ28252.1 - 0.43 11.1 1.8 4 7.9 0.4 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger SUIM_assoc PF16619.5 EEQ28252.1 - 1.1 9.3 14.4 0.14 12.2 2.9 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 C5HCH PF17982.1 EEQ28252.1 - 1.8 8.8 6.1 16 5.8 0.7 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain Pkinase PF00069.25 EEQ28254.1 - 2.6e-52 177.8 0.0 5.3e-34 117.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28254.1 - 1.9e-25 89.7 0.1 8.6e-24 84.2 0.1 3.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ28254.1 - 7.2e-05 21.7 0.3 0.0002 20.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EEQ28254.1 - 0.0013 18.7 0.1 0.0072 16.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ28254.1 - 0.0024 17.2 0.0 0.0069 15.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like DUF2778 PF10908.8 EEQ28254.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) Kelch_5 PF13854.6 EEQ28255.1 - 2.1e-05 24.4 0.0 0.024 14.6 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EEQ28255.1 - 0.0028 17.9 4.8 1.2 9.5 0.0 4.6 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 EEQ28255.1 - 0.0052 16.7 1.2 1.1 9.3 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 EEQ28255.1 - 0.033 14.2 0.1 0.033 14.2 0.1 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain SKG6 PF08693.10 EEQ28255.1 - 0.057 12.8 0.5 0.12 11.8 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain BPL_LplA_LipB PF03099.19 EEQ28256.1 - 0.00042 20.2 0.0 0.0009 19.2 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.21 EEQ28257.1 - 3.7e-137 456.4 0.0 4.2e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ima1_N PF09779.9 EEQ28258.1 - 8.4e-36 123.8 9.6 8.4e-36 123.8 9.6 1.8 2 0 0 2 2 2 1 Ima1 N-terminal domain DZR PF12773.7 EEQ28258.1 - 0.67 10.0 5.1 4.6 7.3 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 EEQ28258.1 - 1.6 8.7 7.6 0.63 10.0 1.4 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) G_path_suppress PF15991.5 EEQ28258.1 - 4.5 7.3 25.9 0.091 12.9 7.4 3.0 3 0 0 3 3 3 0 G-protein pathway suppressor Alg14 PF08660.11 EEQ28259.1 - 2e-51 174.4 0.0 2.7e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PNK3P PF08645.11 EEQ28261.1 - 1e-46 158.6 0.0 2.1e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EEQ28261.1 - 2.3e-26 92.7 0.0 4e-24 85.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EEQ28261.1 - 8.2e-10 38.6 1.7 7.7e-07 28.8 0.0 2.6 2 1 1 3 3 3 2 Chromatin associated protein KTI12 AAA_18 PF13238.6 EEQ28261.1 - 0.012 16.1 0.1 0.049 14.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EEQ28261.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ28261.1 - 0.067 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EEQ28261.1 - 0.072 12.9 0.1 0.5 10.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EEQ28261.1 - 0.076 12.3 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Med18 PF09637.10 EEQ28262.1 - 3.9e-43 148.1 0.0 4.4e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Med18 protein S36_mt PF10937.8 EEQ28263.1 - 3.3e-41 141.5 0.3 3.9e-41 141.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF647 PF04884.14 EEQ28264.1 - 6.2e-85 284.7 15.1 1.2e-48 165.9 2.2 3.1 1 1 1 2 2 2 2 Vitamin B6 photo-protection and homoeostasis PRA1 PF03208.19 EEQ28264.1 - 0.15 11.7 2.0 0.26 10.9 2.0 1.4 1 0 0 1 1 1 0 PRA1 family protein RGS PF00615.19 EEQ28266.1 - 9.5e-10 38.8 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.25 EEQ28269.1 - 1.4e-27 96.7 0.0 1.8e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28269.1 - 2.5e-14 53.2 0.0 3.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ28269.1 - 1.6e-07 30.5 0.0 2.1e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Rtt106 PF08512.12 EEQ28270.1 - 8.2e-31 106.3 0.1 1.5e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Paf1 PF03985.13 EEQ28270.1 - 0.58 9.1 9.9 0.82 8.6 9.9 1.2 1 0 0 1 1 1 0 Paf1 PPP4R2 PF09184.11 EEQ28270.1 - 2 7.9 12.9 3.2 7.3 12.4 1.5 2 0 0 2 2 2 0 PPP4R2 DUF4407 PF14362.6 EEQ28270.1 - 2.2 7.5 3.7 3.6 6.9 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KOW PF00467.29 EEQ28271.1 - 1.8e-06 27.7 0.5 4.1e-06 26.5 0.5 1.6 1 0 0 1 1 1 1 KOW motif Ras PF00071.22 EEQ28272.1 - 1.5e-55 187.2 0.0 1.8e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ28272.1 - 3.3e-22 78.9 0.0 5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ28272.1 - 9.7e-07 28.4 0.0 1.7e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EEQ28272.1 - 0.0024 17.3 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit baeRF_family3 PF18845.1 EEQ28272.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 Gtr1_RagA PF04670.12 EEQ28272.1 - 0.13 11.5 0.0 0.17 11.2 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Podoplanin PF05808.11 EEQ28273.1 - 0.00014 22.0 0.1 0.00026 21.1 0.1 1.4 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.11 EEQ28273.1 - 0.00066 20.1 0.2 0.00066 20.1 0.2 1.7 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glycophorin_A PF01102.18 EEQ28273.1 - 0.00067 19.9 1.0 0.0011 19.2 1.0 1.3 1 0 0 1 1 1 1 Glycophorin A DUF4690 PF15756.5 EEQ28273.1 - 0.0028 18.2 1.7 0.0059 17.2 1.1 1.8 2 0 0 2 2 2 1 Small Novel Rich in Cartilage DUF4124 PF13511.6 EEQ28273.1 - 0.0075 16.6 2.2 0.016 15.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4124) GRA6 PF05084.13 EEQ28273.1 - 0.062 13.3 1.2 0.28 11.1 1.2 1.9 1 1 0 1 1 1 0 Granule antigen protein (GRA6) TMEM154 PF15102.6 EEQ28273.1 - 0.37 10.7 3.6 0.46 10.4 2.9 1.4 1 1 0 1 1 1 0 TMEM154 protein family Aldedh PF00171.22 EEQ28274.1 - 5.7e-144 480.1 0.0 6.7e-144 479.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1712 PF08217.11 EEQ28275.1 - 1.6e-18 66.6 0.0 3.1e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.19 EEQ28276.1 - 7.4e-16 58.4 0.0 1.4e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase adh_short_C2 PF13561.6 EEQ28277.1 - 3.7e-27 95.4 3.0 1.8e-14 53.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ28277.1 - 7e-26 90.9 5.2 3e-24 85.6 5.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ28277.1 - 4.6e-05 23.4 0.1 7.5e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ28277.1 - 0.00093 18.7 0.1 0.0017 17.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.22 EEQ28278.1 - 1e-23 83.8 0.0 1.7e-18 66.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 EEQ28279.1 - 2.5e-26 92.4 0.0 5.2e-26 91.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EEQ28280.1 - 1.5e-48 165.7 0.0 3.7e-28 98.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 EMP24_GP25L PF01105.24 EEQ28281.1 - 4.6e-52 176.6 0.0 6.3e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_S46 PF10459.9 EEQ28281.1 - 0.086 11.5 0.4 0.13 10.9 0.1 1.3 2 0 0 2 2 2 0 Peptidase S46 PspB PF06667.12 EEQ28281.1 - 0.19 11.8 0.5 0.42 10.7 0.5 1.6 1 0 0 1 1 1 0 Phage shock protein B SANT_DAMP1_like PF16282.5 EEQ28282.1 - 7.8e-31 106.1 0.4 1.6e-30 105.1 0.4 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EEQ28282.1 - 1.7e-05 24.8 0.6 1.7e-05 24.8 0.6 2.9 2 2 1 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF1704 PF08014.11 EEQ28282.1 - 0.052 12.6 1.0 0.11 11.5 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) UPF0242 PF06785.11 EEQ28282.1 - 2.2 8.3 9.4 1 9.4 2.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Meth_synt_2 PF01717.18 EEQ28284.1 - 3e-151 503.3 0.0 3.1e-148 493.3 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EEQ28284.1 - 3.4e-117 391.4 0.0 4e-111 371.5 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EEQ28284.1 - 2.8e-05 23.4 0.0 0.022 13.9 0.0 2.7 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) Steroid_dh PF02544.16 EEQ28285.1 - 7e-09 35.8 7.9 0.0028 17.6 0.5 3.9 3 2 1 4 4 4 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EEQ28285.1 - 0.043 13.3 0.2 0.22 11.0 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ufd2P_core PF10408.9 EEQ28286.1 - 5.5e-206 685.9 14.1 6.8e-206 685.7 14.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EEQ28286.1 - 1.6e-23 82.6 2.2 8.4e-23 80.3 0.2 2.8 3 0 0 3 3 3 1 U-box domain Pex14_N PF04695.13 EEQ28286.1 - 1.6 9.4 11.8 59 4.3 0.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1977 PF09320.11 EEQ28287.1 - 1.1e-31 109.2 0.1 2.1e-31 108.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EEQ28287.1 - 4.6e-22 77.9 0.3 8.1e-22 77.1 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Aim19 PF10315.9 EEQ28288.1 - 5.4e-06 26.7 0.7 1.1e-05 25.7 0.6 1.6 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF1772 PF08592.11 EEQ28288.1 - 3.9 7.8 6.9 6.4 7.1 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) CTP_transf_like PF01467.26 EEQ28289.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Ydc2-catalyt PF09159.10 EEQ28291.1 - 7e-96 321.2 0.0 8.8e-96 320.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EEQ28291.1 - 3.9e-05 23.8 0.0 0.86 9.7 0.0 3.2 3 0 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.27 EEQ28291.1 - 0.00013 21.6 0.5 0.00028 20.6 0.5 1.5 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 EEQ28291.1 - 0.1 12.5 0.1 0.27 11.2 0.1 1.8 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Tcp11 PF05794.13 EEQ28292.1 - 5.5e-94 315.8 0.0 5.5e-94 315.8 0.0 1.3 2 0 0 2 2 2 1 T-complex protein 11 LIN37 PF15306.6 EEQ28292.1 - 0.33 11.2 3.6 0.84 9.8 3.6 1.6 1 0 0 1 1 1 0 LIN37 Peptidase_S10 PF00450.22 EEQ28293.1 - 5.6e-77 259.9 0.0 1.2e-76 258.9 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase SOG2 PF10428.9 EEQ28294.1 - 3.9e-102 343.1 0.8 4.7e-58 197.6 1.0 4.2 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 EEQ28294.1 - 4e-13 48.9 3.5 3.4e-07 29.9 1.3 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EEQ28294.1 - 2e-12 47.1 6.1 8.5e-05 22.8 1.3 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EEQ28294.1 - 0.055 14.0 8.6 10 7.2 0.2 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EEQ28294.1 - 0.055 13.5 3.7 3.3 8.0 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Big_2 PF02368.18 EEQ28294.1 - 0.081 12.8 0.4 0.2 11.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) CCDC53 PF10152.9 EEQ28294.1 - 0.096 13.1 2.2 1.4 9.4 0.3 2.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex MRP-S25 PF13741.6 EEQ28295.1 - 6.4e-82 274.6 4.4 7.5e-82 274.3 4.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EEQ28295.1 - 0.0021 18.3 4.9 1 9.6 0.0 3.1 1 1 2 3 3 3 2 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 EEQ28296.1 - 1e-10 41.7 0.2 0.0011 19.1 0.0 4.7 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 EEQ28296.1 - 2.2e-07 30.7 1.3 0.15 12.4 0.1 4.3 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EEQ28296.1 - 0.00098 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EEQ28296.1 - 0.042 13.9 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DEAD PF00270.29 EEQ28297.1 - 3.4e-15 56.3 0.0 1.5e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ28297.1 - 8e-14 51.9 0.0 8.3e-11 42.2 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EEQ28297.1 - 4.3e-05 24.2 1.3 0.00014 22.5 0.4 2.3 2 0 0 2 2 2 1 RecQ zinc-binding Myotub-related PF06602.14 EEQ28297.1 - 0.13 11.2 0.1 0.39 9.6 0.1 1.7 1 1 0 1 1 1 0 Myotubularin-like phosphatase domain Tom6 PF17112.5 EEQ28297.1 - 0.32 10.5 1.3 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal KH_1 PF00013.29 EEQ28298.1 - 4.3e-08 32.9 0.0 3.1e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 KH domain ATLF PF07737.11 EEQ28298.1 - 0.039 13.2 0.0 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain GRP PF07172.11 EEQ28298.1 - 4.7 8.0 19.8 0.11 13.2 12.4 2.0 2 0 0 2 2 2 0 Glycine rich protein family ALS_ss_C PF10369.9 EEQ28299.1 - 2.5e-15 56.4 0.0 6.4e-14 51.9 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EEQ28299.1 - 2e-12 46.7 0.2 3.6e-12 45.8 0.2 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EEQ28299.1 - 4.8e-08 32.7 0.0 9.1e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EEQ28299.1 - 0.027 14.4 0.1 11 6.1 0.0 2.7 2 0 0 2 2 2 0 ACT domain Cu-oxidase_3 PF07732.15 EEQ28303.1 - 3.6e-38 130.2 0.1 6.4e-37 126.2 0.2 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EEQ28303.1 - 3.3e-37 127.3 5.4 9.4e-35 119.3 1.2 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EEQ28303.1 - 7.5e-25 87.9 0.0 2.2e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase DUF3712 PF12505.8 EEQ28304.1 - 3.2e-07 30.6 0.3 0.00063 20.0 0.0 3.7 4 2 0 4 4 4 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EEQ28304.1 - 0.0042 17.6 0.5 2.6 8.6 0.1 3.4 3 0 0 3 3 3 2 Late embryogenesis abundant protein OTCace PF00185.24 EEQ28305.1 - 2.9e-44 150.9 0.0 4.5e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EEQ28305.1 - 1.1e-42 145.6 0.0 1.5e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_hydro_101 PF12905.7 EEQ28305.1 - 0.048 13.1 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase DUF3984 PF13136.6 EEQ28306.1 - 1.2e-107 360.1 19.5 1.7e-107 359.6 19.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Ndc1_Nup PF09531.10 EEQ28307.1 - 5.7e-200 666.1 0.9 6.5e-200 665.9 0.9 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 EEQ28308.1 - 1.5e-23 83.0 9.3 2.8e-23 82.2 2.1 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EEQ28308.1 - 4.9e-14 52.1 2.2 4.9e-14 52.1 2.2 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 EEQ28308.1 - 3.7e-05 23.5 8.8 0.00013 21.7 8.8 2.0 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 EEQ28308.1 - 0.00012 21.8 1.1 0.0004 20.1 0.3 2.1 2 0 0 2 2 2 1 Synaptobrevin DUF883 PF05957.13 EEQ28308.1 - 0.02 15.5 10.4 0.28 11.8 0.2 3.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) T3SSipB PF16535.5 EEQ28308.1 - 0.03 14.8 7.3 0.075 13.5 3.5 2.5 3 0 0 3 3 3 0 Type III cell invasion protein SipB K_channel_TID PF07941.11 EEQ28308.1 - 0.039 14.4 1.4 0.039 14.4 1.4 2.0 3 0 0 3 3 2 0 Potassium channel Kv1.4 tandem inactivation domain Prominin PF05478.11 EEQ28308.1 - 0.071 11.1 3.3 0.27 9.1 3.2 1.9 1 1 0 1 1 1 0 Prominin DUF5345 PF17280.2 EEQ28308.1 - 0.14 12.1 1.4 0.41 10.6 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF16 PF01519.16 EEQ28308.1 - 0.17 12.4 6.2 10 6.6 6.2 2.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 Orf78 PF06024.12 EEQ28308.1 - 0.19 12.1 0.2 0.54 10.6 0.2 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Fib_alpha PF08702.10 EEQ28308.1 - 0.21 11.8 4.5 0.52 10.5 0.1 3.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family ISG65-75 PF11727.8 EEQ28308.1 - 0.74 9.0 5.8 1.2 8.3 1.6 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein CENP-H PF05837.12 EEQ28308.1 - 6 7.3 10.1 4.7 7.7 2.5 3.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Cyto_heme_lyase PF01265.17 EEQ28309.1 - 5.7e-40 137.7 2.7 1.9e-35 122.9 0.3 2.6 1 1 0 2 2 2 2 Cytochrome c/c1 heme lyase MDD_C PF18376.1 EEQ28310.1 - 5.4e-62 208.9 0.0 7.4e-62 208.4 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EEQ28310.1 - 2.7e-10 40.3 1.7 6.6e-10 39.1 1.7 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain IKI3 PF04762.12 EEQ28311.1 - 2e-299 995.8 0.0 3.3e-299 995.1 0.0 1.3 1 1 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EEQ28311.1 - 0.0009 19.5 0.1 2.5 8.4 0.0 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain COX7C PF02935.16 EEQ28312.1 - 7.5e-19 67.7 4.8 1.1e-18 67.2 4.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 EEQ28313.1 - 8.8e-91 304.6 0.1 2e-90 303.4 0.1 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EEQ28313.1 - 2.6e-54 183.3 1.7 8.5e-54 181.6 1.7 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EEQ28313.1 - 1.7e-18 67.0 0.1 6.4e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ28313.1 - 2.9e-06 27.6 0.2 1.6e-05 25.2 0.2 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ28313.1 - 3.1e-05 24.0 0.0 8.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EEQ28313.1 - 0.076 12.1 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EEQ28313.1 - 0.14 12.4 0.0 0.65 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 EEQ28314.1 - 0.042 13.6 0.6 0.055 13.2 0.6 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component LPG_synthase_TM PF03706.13 EEQ28314.1 - 0.058 12.9 0.6 0.073 12.6 0.6 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Pkinase PF00069.25 EEQ28315.1 - 4.5e-17 62.3 0.0 1.8e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28315.1 - 2.3e-10 40.2 0.0 4.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EEQ28315.1 - 0.0002 21.0 0.1 0.00034 20.3 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EEQ28315.1 - 0.017 15.1 0.1 0.036 14.0 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EEQ28315.1 - 0.077 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cut8 PF08559.10 EEQ28316.1 - 5.8e-60 202.9 0.0 8.7e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein HalOD1 PF18545.1 EEQ28316.1 - 0.094 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Halobacterial output domain 1 Motile_Sperm PF00635.26 EEQ28317.1 - 9.2e-06 25.5 0.2 0.15 11.9 0.0 2.5 2 1 0 2 2 2 2 MSP (Major sperm protein) domain Trypan_PARP PF05887.11 EEQ28317.1 - 0.094 12.7 2.6 0.058 13.4 0.6 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) UBX PF00789.20 EEQ28318.1 - 1.9e-05 24.8 0.1 8.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 EEQ28318.1 - 0.00066 19.5 0.0 0.0021 17.9 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_6 PF13912.6 EEQ28318.1 - 0.074 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Exonuc_VII_L PF02601.15 EEQ28318.1 - 0.16 11.5 10.8 0.21 11.1 10.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF29 PF01724.16 EEQ28318.1 - 0.16 12.2 15.8 0.35 11.1 15.8 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF29 zf-C2H2_2 PF12756.7 EEQ28318.1 - 0.16 12.3 0.4 0.16 12.3 0.4 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EEQ28318.1 - 0.17 12.4 0.2 0.32 11.5 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF572 PF04502.13 EEQ28318.1 - 0.51 9.9 27.4 0.044 13.4 22.8 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) FapA PF03961.13 EEQ28318.1 - 3.5 6.1 19.0 5.5 5.5 19.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CRT10 PF08728.10 EEQ28318.1 - 6.4 4.8 8.9 7.8 4.5 8.9 1.1 1 0 0 1 1 1 0 CRT10 Rad52_Rad22 PF04098.15 EEQ28319.1 - 2.9e-38 131.2 0.7 3.8e-21 75.6 0.7 2.3 1 1 1 2 2 2 2 Rad52/22 family double-strand break repair protein IIGP PF05049.13 EEQ28319.1 - 0.043 12.9 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Aa_trans PF01490.18 EEQ28321.1 - 5.2e-80 269.2 31.6 6.3e-80 268.9 31.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4131 PF13567.6 EEQ28321.1 - 7 6.3 9.1 13 5.4 0.3 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Y_phosphatase2 PF03162.13 EEQ28323.1 - 1.1e-29 103.2 0.1 9.2e-28 96.9 0.1 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EEQ28323.1 - 0.0025 17.4 0.0 0.0059 16.2 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 EEQ28323.1 - 0.0046 16.8 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EEQ28323.1 - 0.032 14.2 0.0 0.058 13.4 0.0 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 EEQ28323.1 - 0.17 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TatD_DNase PF01026.21 EEQ28324.1 - 1.5e-48 165.4 0.0 1.8e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.18 EEQ28325.1 - 3.1e-114 381.6 0.0 3.7e-114 381.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EEQ28325.1 - 4.5e-13 49.2 0.1 5.2e-12 45.7 0.1 2.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EEQ28325.1 - 0.00034 19.9 0.0 0.00052 19.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 EEQ28325.1 - 0.00038 19.9 0.0 0.036 13.4 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 EEQ28325.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EEQ28325.1 - 0.011 14.8 0.3 0.024 13.7 0.1 1.7 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain VID27_N PF17748.1 EEQ28325.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 VID27 N-terminal region BtpA PF03437.15 EEQ28325.1 - 0.13 11.7 0.0 0.92 8.9 0.0 2.1 2 0 0 2 2 2 0 BtpA family SAP PF02037.27 EEQ28326.1 - 1.5e-10 40.6 0.0 2.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain PCMT PF01135.19 EEQ28326.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FANC_SAP PF18081.1 EEQ28326.1 - 0.93 9.7 3.3 5.7 7.2 0.1 2.5 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain RNA_pol_Rpb1_1 PF04997.12 EEQ28327.1 - 2.5e-82 276.7 1.1 4.1e-82 276.0 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EEQ28327.1 - 5.4e-80 268.7 0.4 9.7e-80 267.8 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EEQ28327.1 - 1.5e-71 239.9 0.0 2.8e-71 239.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EEQ28327.1 - 6.1e-34 117.2 0.0 1.2e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EEQ28327.1 - 1.3e-25 89.4 0.3 4e-25 87.8 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Asp PF00026.23 EEQ28328.1 - 5e-47 160.9 0.0 6.5e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease CarboxypepD_reg PF13620.6 EEQ28329.1 - 0.029 14.7 2.1 0.11 12.7 0.8 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Vfa1 PF08432.10 EEQ28330.1 - 2.7e-59 200.5 26.7 3.3e-59 200.2 26.7 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4746 PF15928.5 EEQ28330.1 - 0.0054 16.2 13.6 0.006 16.1 13.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) CDC45 PF02724.14 EEQ28330.1 - 0.0078 14.6 16.5 0.0076 14.6 16.5 1.1 1 0 0 1 1 1 1 CDC45-like protein RR_TM4-6 PF06459.12 EEQ28330.1 - 0.015 15.1 21.5 0.021 14.7 21.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 EEQ28330.1 - 0.066 12.0 15.8 0.076 11.8 15.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 EEQ28330.1 - 0.093 11.7 7.8 0.11 11.4 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 EEQ28330.1 - 0.18 11.9 7.1 0.2 11.7 7.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 EEQ28330.1 - 0.27 11.4 8.2 0.33 11.1 8.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF262 PF03235.14 EEQ28330.1 - 0.46 10.6 10.2 0.54 10.4 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 SpoIIP PF07454.11 EEQ28330.1 - 0.56 9.6 17.7 0.76 9.2 17.7 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 EEQ28330.1 - 0.6 9.1 15.8 0.69 8.9 15.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 EEQ28330.1 - 0.62 8.4 4.2 0.71 8.2 4.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_11 PF13086.6 EEQ28330.1 - 0.65 9.7 13.8 0.84 9.4 13.8 1.3 1 0 0 1 1 1 0 AAA domain SAPS PF04499.15 EEQ28330.1 - 0.69 8.6 12.0 0.74 8.5 12.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC27 PF09507.10 EEQ28330.1 - 1.3 8.4 35.4 1.5 8.1 35.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2828 PF11443.8 EEQ28330.1 - 1.3 7.0 14.9 1.5 6.8 14.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 EEQ28330.1 - 1.7 7.4 16.0 2 7.1 16.0 1.1 1 0 0 1 1 1 0 Presenilin DUF908 PF06012.12 EEQ28330.1 - 1.9 7.9 8.0 2.3 7.6 8.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CLN3 PF02487.17 EEQ28330.1 - 1.9 7.5 6.2 2.2 7.2 6.2 1.3 1 0 0 1 1 1 0 CLN3 protein GCD14 PF08704.10 EEQ28330.1 - 3.2 7.4 10.9 4.8 6.8 10.9 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ALMT PF11744.8 EEQ28330.1 - 3.7 6.3 14.1 4.5 6.0 14.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter U79_P34 PF03064.16 EEQ28330.1 - 4.2 6.6 29.9 8.8 5.6 29.9 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Paramyxo_ncap PF00973.19 EEQ28330.1 - 5.8 5.7 13.1 7 5.4 13.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PA26 PF04636.13 EEQ28330.1 - 6.9 5.5 11.2 8.4 5.2 11.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ATP11 PF06644.11 EEQ28330.1 - 8.3 6.1 21.8 11 5.7 21.8 1.1 1 0 0 1 1 1 0 ATP11 protein DSPc PF00782.20 EEQ28331.1 - 3.5e-22 78.6 0.0 4.5e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EEQ28331.1 - 0.003 17.8 0.0 0.0061 16.8 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EEQ28331.1 - 0.056 13.0 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-H2C2_2 PF13465.6 EEQ28333.1 - 0.015 15.7 1.2 0.015 15.7 1.2 3.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.26 EEQ28333.1 - 0.017 15.6 4.3 0.017 15.6 4.3 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EEQ28333.1 - 0.047 14.0 5.1 0.14 12.5 5.1 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF2614 PF11023.8 EEQ28333.1 - 0.19 11.8 0.3 0.33 11.1 0.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Cytochrome_C7 PF14522.6 EEQ28333.1 - 2.3 8.3 12.9 6.4 6.9 12.9 1.8 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-C2H2_4 PF13894.6 EEQ28333.1 - 6.3 7.9 21.4 0.75 10.8 3.0 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger FA_desaturase PF00487.24 EEQ28334.1 - 1.3e-25 90.7 10.7 1.9e-25 90.2 10.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EEQ28334.1 - 2.5e-17 62.1 0.9 2.5e-17 62.1 0.9 1.7 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) ABC1 PF03109.16 EEQ28335.1 - 1e-33 116.0 0.1 2.3e-33 114.9 0.0 1.7 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.22 EEQ28335.1 - 0.026 14.1 0.0 0.067 12.8 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Anp1 PF03452.14 EEQ28336.1 - 4e-94 314.9 1.1 4.6e-93 311.4 1.1 2.0 1 1 0 1 1 1 1 Anp1 Glyco_transf_7N PF13733.6 EEQ28336.1 - 0.18 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Ecm33 PF12454.8 EEQ28337.1 - 1.1e-16 60.7 3.3 3.6e-16 59.0 0.3 2.7 1 1 1 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 EEQ28337.1 - 3.5e-09 36.8 1.2 1.4 9.0 0.0 5.4 1 1 3 4 4 4 4 Receptor L domain HhH-GPD PF00730.25 EEQ28338.1 - 8.5e-14 51.9 0.0 1.8e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UCR_14kD PF02271.16 EEQ28339.1 - 5.9e-43 144.9 0.3 6.8e-43 144.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 EEQ28340.1 - 1.9e-63 210.4 0.6 2.4e-21 75.5 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein CHD5 PF04420.14 EEQ28341.1 - 2.8e-58 196.3 2.6 3.4e-58 196.0 2.6 1.0 1 0 0 1 1 1 1 CHD5-like protein HetR_C PF18460.1 EEQ28341.1 - 0.028 14.3 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain SUI1 PF01253.22 EEQ28342.1 - 5.3e-19 68.5 0.0 1.4e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EEQ28342.1 - 1.6e-06 28.7 0.1 0.00012 22.7 0.1 2.9 1 1 0 1 1 1 1 Pre-PUA-like domain Trypsin PF00089.26 EEQ28343.1 - 6.7e-07 29.3 0.9 2.5e-06 27.5 0.9 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EEQ28343.1 - 0.053 14.4 0.0 0.15 12.9 0.0 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain PUMA PF15826.5 EEQ28344.1 - 0.033 14.4 0.1 0.037 14.2 0.1 1.2 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis TIG PF01833.24 EEQ28345.1 - 2.8e-09 36.9 1.5 5.5e-09 36.0 0.2 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank PF00023.30 EEQ28345.1 - 1.4e-08 34.8 5.9 0.0025 18.2 3.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EEQ28345.1 - 8.3e-08 32.4 2.3 0.00029 21.1 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ28345.1 - 8.8e-07 29.4 0.0 1.8e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ28345.1 - 3.4e-06 27.5 0.8 1.6e-05 25.4 0.3 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ28345.1 - 3.9e-05 23.7 0.8 0.084 13.5 0.4 2.8 2 0 0 2 2 2 2 Ankyrin repeat Bap31 PF05529.12 EEQ28345.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region TRAPPC10 PF12584.8 EEQ28346.1 - 1.4e-41 141.8 0.0 2.5e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Ribosomal_60s PF00428.19 EEQ28346.1 - 0.11 13.1 11.8 0.24 12.0 7.9 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Foie-gras_1 PF11817.8 EEQ28346.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 CDC45 PF02724.14 EEQ28346.1 - 0.15 10.3 2.7 0.22 9.7 2.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 EEQ28346.1 - 0.18 11.7 7.2 0.36 10.7 7.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region FYDLN_acid PF09538.10 EEQ28346.1 - 0.34 11.6 8.3 0.84 10.3 8.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RXT2_N PF08595.11 EEQ28346.1 - 0.53 10.3 3.9 1.1 9.3 3.9 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 EEQ28346.1 - 0.56 8.4 6.8 0.96 7.6 6.8 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EEQ28346.1 - 3.4 6.9 13.0 5.5 6.2 13.0 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EEQ28346.1 - 4.2 7.6 13.8 7.4 6.8 13.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 EEQ28346.1 - 7 6.3 6.4 13 5.4 6.4 1.4 1 0 0 1 1 1 0 FAM176 family FA_desaturase PF00487.24 EEQ28347.1 - 9.6e-22 78.0 19.3 6e-21 75.4 19.3 2.0 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EEQ28347.1 - 1.7e-08 34.8 0.0 4.4e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Rad51 PF08423.11 EEQ28348.1 - 1.4e-37 129.3 0.0 1.3e-35 122.9 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 EEQ28348.1 - 4.5e-07 29.6 0.0 7.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EEQ28348.1 - 4.7e-05 22.8 0.1 0.00033 20.1 0.1 2.2 1 1 0 1 1 1 1 KaiC RecA PF00154.21 EEQ28348.1 - 0.046 13.2 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_24 PF13479.6 EEQ28348.1 - 0.098 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DAO PF01266.24 EEQ28349.1 - 3.1e-45 155.3 0.3 4.5e-45 154.7 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EEQ28349.1 - 8.8e-06 25.1 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EEQ28349.1 - 1.9e-05 24.8 0.1 4.9e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EEQ28349.1 - 0.0035 16.5 0.0 0.0064 15.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EEQ28349.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EEQ28349.1 - 0.059 12.4 0.4 0.11 11.6 0.3 1.5 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 EEQ28349.1 - 0.059 13.6 0.1 3.7 7.8 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 EEQ28349.1 - 0.076 12.2 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ28349.1 - 0.12 11.4 0.2 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Mqo PF06039.15 EEQ28349.1 - 0.16 10.5 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) La PF05383.17 EEQ28350.1 - 2.5e-21 75.5 0.0 4.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EEQ28350.1 - 1e-05 25.3 0.1 3.3e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chitin_synth_2 PF03142.15 EEQ28351.1 - 3.7e-23 81.9 4.9 3.4e-22 78.8 2.1 2.4 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EEQ28351.1 - 3.9e-16 59.5 7.1 3.9e-16 59.5 7.1 1.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EEQ28351.1 - 9.4e-12 45.3 0.0 2.1e-11 44.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EEQ28351.1 - 0.0018 18.1 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EEQ28351.1 - 0.32 10.4 1.5 4.5 6.7 1.5 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 21 HSP70 PF00012.20 EEQ28352.1 - 5.8e-158 526.8 0.6 2.7e-139 465.1 0.1 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EEQ28352.1 - 3e-10 39.4 0.3 6.2e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EEQ28352.1 - 0.06 13.8 0.3 6.6 7.2 0.0 3.0 2 1 0 2 2 2 0 Cell division protein FtsA DUF2570 PF10828.8 EEQ28352.1 - 0.42 10.5 3.8 2.3 8.1 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Thiolase_N PF00108.23 EEQ28353.1 - 2.2e-71 240.3 0.6 3.2e-71 239.7 0.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EEQ28353.1 - 2.5e-41 140.2 0.5 5.5e-41 139.1 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EEQ28353.1 - 0.013 15.3 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EEQ28353.1 - 0.02 14.5 1.2 0.11 12.0 1.1 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain SMG1 PF15785.5 EEQ28353.1 - 0.06 11.7 0.0 0.078 11.3 0.0 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 WLM PF08325.10 EEQ28354.1 - 8.9e-51 172.7 0.0 1.3e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EEQ28354.1 - 8.8e-05 22.6 0.2 0.00086 19.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 ubiquitin PF00240.23 EEQ28354.1 - 0.028 14.2 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin family SprT-like PF10263.9 EEQ28354.1 - 0.044 13.7 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 SprT-like family LicD PF04991.13 EEQ28355.1 - 1.9e-22 80.6 1.5 2.1e-18 67.3 0.6 2.1 1 1 1 2 2 2 2 LicD family AcetylCoA_hyd_C PF13336.6 EEQ28355.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain DASH_Ask1 PF08655.10 EEQ28357.1 - 3.9e-23 81.1 0.6 7.6e-23 80.2 0.6 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 RhoGAP PF00620.27 EEQ28358.1 - 1.3e-45 154.9 0.1 4.7e-45 153.1 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EEQ28358.1 - 8.2e-14 51.6 18.5 2.9e-09 37.0 2.7 2.4 2 0 0 2 2 2 2 LIM domain Fez1 PF06818.15 EEQ28358.1 - 7.3 7.0 23.0 0.4 11.1 13.7 3.0 2 1 1 3 3 3 0 Fez1 TF_Zn_Ribbon PF08271.12 EEQ28358.1 - 8.7 6.0 17.6 33 4.1 0.1 4.4 3 1 0 3 3 3 0 TFIIB zinc-binding APH PF01636.23 EEQ28360.1 - 0.00047 20.2 0.1 0.00047 20.2 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family 4HBT PF03061.22 EEQ28362.1 - 1.8e-07 31.4 0.1 2.7e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EEQ28362.1 - 0.018 15.3 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Carn_acyltransf PF00755.20 EEQ28363.1 - 4.4e-208 692.7 0.0 5.2e-208 692.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase JmjC PF02373.22 EEQ28364.1 - 2.1e-38 131.3 0.9 5e-38 130.0 0.5 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.6 EEQ28364.1 - 6.2e-19 68.1 2.8 1.2e-18 67.2 2.8 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EEQ28364.1 - 5.8e-18 65.1 2.5 9.8e-18 64.3 2.5 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.17 EEQ28364.1 - 4.4e-14 52.2 0.3 1.2e-13 50.8 0.3 1.8 1 0 0 1 1 1 1 jmjN domain PhyH PF05721.13 EEQ28367.1 - 0.0017 18.7 0.0 0.0035 17.6 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Arteri_Gl PF00951.18 EEQ28371.1 - 0.19 11.5 2.0 0.34 10.7 2.0 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein LysM PF01476.20 EEQ28372.1 - 6e-08 32.6 0.1 0.0017 18.4 0.0 2.9 3 0 0 3 3 3 2 LysM domain AA_permease_2 PF13520.6 EEQ28373.1 - 7.1e-65 219.5 52.2 8.6e-65 219.2 52.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ28373.1 - 5.8e-31 107.6 46.6 7.7e-31 107.2 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease Cyclase PF04199.13 EEQ28374.1 - 2.5e-14 53.7 0.0 6.6e-14 52.3 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase PEP_mutase PF13714.6 EEQ28375.1 - 1e-63 215.0 0.0 1.2e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MinE PF03776.14 EEQ28375.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE DHDPS PF00701.22 EEQ28377.1 - 3.1e-34 118.0 0.0 1.3e-32 112.7 0.0 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Ribonuc_L-PSP PF01042.21 EEQ28378.1 - 2.2e-39 134.2 0.1 2.4e-39 134.1 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP QRPTase_C PF01729.19 EEQ28378.1 - 0.03 14.1 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain D-ser_dehydrat PF14031.6 EEQ28379.1 - 3.1e-25 88.6 0.0 6.3e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EEQ28379.1 - 2.6e-12 46.9 0.0 3.9e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Velvet PF11754.8 EEQ28381.1 - 1.2e-52 179.4 10.1 1.9e-32 113.2 0.0 3.1 1 1 2 3 3 3 2 Velvet factor PPTA PF01239.22 EEQ28383.1 - 0.014 15.1 7.2 1.3 8.8 2.2 3.2 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat AA_permease_2 PF13520.6 EEQ28385.1 - 8.5e-44 150.0 52.8 1.1e-43 149.7 52.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ28385.1 - 8e-23 80.8 50.1 2.4e-22 79.2 50.1 1.6 1 1 0 1 1 1 1 Amino acid permease DUF1435 PF07256.12 EEQ28385.1 - 7.6 6.7 8.9 0.65 10.1 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1435) TRAM_LAG1_CLN8 PF03798.16 EEQ28386.1 - 1e-39 136.4 23.0 1e-39 136.4 23.0 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EEQ28386.1 - 3.5e-13 49.0 0.2 3.5e-13 49.0 0.2 2.2 2 0 0 2 2 2 1 TRAM1-like protein RRM_1 PF00076.22 EEQ28387.1 - 5e-15 55.1 0.0 1.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ28387.1 - 0.049 13.8 0.1 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EEQ28387.1 - 0.089 12.8 0.1 0.34 10.9 0.1 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 EEQ28387.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 RL domain SMN PF06003.12 EEQ28388.1 - 1.2e-05 24.7 7.8 4.1e-05 23.0 2.4 2.4 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) DUF4419 PF14388.6 EEQ28388.1 - 0.085 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) APH PF01636.23 EEQ28389.1 - 1.8e-10 41.2 0.7 2.7e-08 34.0 0.2 2.7 3 0 0 3 3 3 2 Phosphotransferase enzyme family EcKinase PF02958.20 EEQ28389.1 - 0.037 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Thiolase_N PF00108.23 EEQ28390.1 - 6.7e-15 55.1 0.1 1.1e-13 51.2 0.1 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EEQ28390.1 - 1.3e-11 44.2 2.4 1.7e-10 40.6 0.0 2.8 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EEQ28390.1 - 1.3e-07 31.4 0.0 1e-05 25.3 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EEQ28390.1 - 0.0047 16.5 0.5 0.01 15.4 0.5 1.5 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EEQ28390.1 - 0.017 13.9 0.5 0.042 12.6 0.1 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Mito_carr PF00153.27 EEQ28391.1 - 3.9e-35 119.6 8.0 1.1e-15 57.4 0.5 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein BRO1 PF03097.18 EEQ28392.1 - 1.1e-116 389.8 2.5 1.2e-115 386.5 0.0 2.7 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EEQ28392.1 - 7.8e-85 284.7 14.6 7.8e-85 284.7 14.6 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Cellulase-like PF12876.7 EEQ28392.1 - 0.078 12.3 0.7 0.43 9.9 0.1 2.0 2 0 0 2 2 2 0 Sugar-binding cellulase-like GAS PF13851.6 EEQ28392.1 - 7.7 5.8 14.4 0.26 10.6 5.2 3.1 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 EEQ28393.1 - 9.4e-13 48.0 13.0 1.8e-12 47.1 13.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EEQ28393.1 - 3.5e-06 27.0 11.6 7.2e-06 26.0 11.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor TFIIA PF03153.13 EEQ28393.1 - 0.0043 17.1 16.4 0.0048 17.0 16.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 EEQ28393.1 - 0.23 11.5 2.6 0.35 10.9 2.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4094 PF13334.6 EEQ28393.1 - 1.6 9.2 6.3 0.16 12.4 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) SOGA PF11365.8 EEQ28393.1 - 1.8 9.8 8.3 0.17 13.0 2.6 2.3 3 0 0 3 3 3 0 Protein SOGA TSC22 PF01166.18 EEQ28393.1 - 5.1 7.5 8.6 0.34 11.2 0.8 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family Ndc1_Nup PF09531.10 EEQ28393.1 - 5.9 5.5 13.4 8.1 5.0 13.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AICARFT_IMPCHas PF01808.18 EEQ28395.1 - 3.6e-91 305.7 0.0 6.1e-91 304.9 0.0 1.4 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EEQ28395.1 - 3.9e-24 84.6 0.0 6.9e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain RdRP PF05183.12 EEQ28396.1 - 0.076 11.6 0.0 0.094 11.3 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase FKBP_C PF00254.28 EEQ28399.1 - 5.6e-12 45.8 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-C2H2_4 PF13894.6 EEQ28399.1 - 0.079 13.8 0.4 0.079 13.8 0.4 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger DUF3580 PF12117.8 EEQ28400.1 - 0.036 14.3 0.1 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) PAH PF02671.21 EEQ28402.1 - 8.5e-11 41.8 0.0 2.1e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Paired amphipathic helix repeat CENP-N PF05238.13 EEQ28403.1 - 1.1e-117 393.9 3.1 2.8e-117 392.5 3.1 1.6 1 1 0 1 1 1 1 Kinetochore protein CHL4 like zf-RING_2 PF13639.6 EEQ28404.1 - 3.4e-07 30.5 6.3 3.4e-07 30.5 6.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 EEQ28404.1 - 1.3e-06 28.3 5.2 3.5e-06 27.0 1.9 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SWIM PF04434.17 EEQ28404.1 - 7.8e-05 22.2 0.5 0.00015 21.4 0.5 1.5 1 0 0 1 1 1 1 SWIM zinc finger Prok-RING_1 PF14446.6 EEQ28404.1 - 0.00039 20.3 1.4 0.00039 20.3 1.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.6 EEQ28404.1 - 0.006 16.6 3.3 0.016 15.3 3.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EEQ28404.1 - 0.011 15.5 6.1 0.011 15.5 6.1 1.6 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EEQ28404.1 - 0.014 15.6 10.5 0.028 14.6 6.9 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 EEQ28404.1 - 0.032 14.2 6.1 0.032 14.2 6.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain RINGv PF12906.7 EEQ28404.1 - 0.055 13.6 7.9 0.12 12.5 7.9 1.6 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 EEQ28404.1 - 0.066 13.1 6.5 0.14 12.0 6.5 1.6 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 EEQ28404.1 - 0.22 11.5 6.8 0.18 11.7 2.6 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 EEQ28404.1 - 0.58 10.5 9.7 0.073 13.4 4.7 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain SCRL PF06876.12 EEQ28404.1 - 1.3 9.3 8.4 0.21 11.8 1.1 2.3 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein zf-C3HC4_3 PF13920.6 EEQ28404.1 - 2.2 8.2 7.4 0.54 10.2 3.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EEQ28404.1 - 9 6.7 10.8 0.49 10.7 4.2 2.3 3 0 0 3 3 3 0 RING-like domain zf-C3HC4_2 PF13923.6 EEQ28404.1 - 9 6.2 8.5 2.9 7.8 4.1 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF974 PF06159.13 EEQ28405.1 - 1.6e-75 254.1 0.0 1.9e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.21 EEQ28407.1 - 8.9e-58 195.3 0.1 2e-57 194.2 0.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EEQ28407.1 - 7.3e-15 55.5 0.0 2.7e-14 53.6 0.0 2.1 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EEQ28407.1 - 4.2e-14 52.3 0.4 9.8e-14 51.1 0.4 1.7 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 EEQ28407.1 - 1.2e-06 28.7 5.2 2.7e-06 27.6 5.2 1.6 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 EEQ28407.1 - 0.00064 19.6 4.9 0.0012 18.7 4.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EEQ28407.1 - 0.18 11.9 5.6 0.38 10.9 5.6 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Vps39_2 PF10367.9 EEQ28407.1 - 1.2 9.6 2.7 2.6 8.5 2.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 PHD PF00628.29 EEQ28407.1 - 1.4 8.8 8.2 0.95 9.4 6.2 1.7 1 1 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 EEQ28407.1 - 2.8 7.6 7.5 5.1 6.8 7.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD_2 PF13831.6 EEQ28407.1 - 3.9 7.1 6.4 2.7 7.6 4.2 1.8 1 1 1 2 2 2 0 PHD-finger RTA1 PF04479.13 EEQ28408.1 - 2.5e-67 226.5 14.0 3.8e-67 225.9 14.0 1.3 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.8 EEQ28409.1 - 0.016 14.0 0.8 0.023 13.5 0.8 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain SLATT_fungal PF18142.1 EEQ28410.1 - 1.3e-33 115.6 0.0 1.7e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain DUF1507 PF07408.11 EEQ28410.1 - 0.07 13.0 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) Ank_2 PF12796.7 EEQ28412.1 - 0.00086 19.8 0.0 0.0011 19.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ28412.1 - 0.0048 17.2 0.1 0.053 13.9 0.2 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ28412.1 - 0.011 16.3 0.0 0.27 11.8 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 EEQ28412.1 - 0.11 13.0 0.0 0.88 10.1 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeat HATPase_c_3 PF13589.6 EEQ28413.1 - 8.3e-20 71.0 0.0 1.5e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 EEQ28413.1 - 2.5e-12 46.8 0.0 9.4e-11 41.7 0.0 2.4 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 EEQ28413.1 - 4.2e-08 33.7 0.1 8e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RasGEF PF00617.19 EEQ28414.1 - 4.9e-52 176.7 0.9 9.1e-52 175.8 0.9 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EEQ28414.1 - 7.9e-15 55.0 0.0 3.2e-14 53.0 0.0 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 EEQ28414.1 - 9.9e-07 28.5 0.0 2.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEQ28414.1 - 3.1e-05 23.5 0.0 6.9e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain GHMP_kinases_N PF00288.26 EEQ28416.1 - 2.1e-11 43.9 0.1 4.4e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEQ28416.1 - 6.1e-05 23.3 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Med5 PF08689.10 EEQ28417.1 - 4.8e-138 461.8 0.0 1.3e-136 457.1 0.0 2.7 1 1 0 1 1 1 1 Mediator complex subunit Med5 ELFV_dehydrog PF00208.21 EEQ28420.1 - 1.2e-80 270.7 1.6 1.5e-80 270.4 1.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EEQ28420.1 - 2.3e-40 137.5 0.0 4.6e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DPBB_1 PF03330.18 EEQ28421.1 - 0.0065 16.7 0.0 0.018 15.3 0.0 1.8 1 1 0 1 1 1 1 Lytic transglycolase MFS_1 PF07690.16 EEQ28423.1 - 2.7e-09 36.4 29.5 2.7e-09 36.4 29.5 3.7 2 2 1 3 3 3 2 Major Facilitator Superfamily Chloroa_b-bind PF00504.21 EEQ28423.1 - 0.24 11.9 2.1 0.57 10.7 0.1 2.7 3 0 0 3 3 3 0 Chlorophyll A-B binding protein Ribonuc_red_lgC PF02867.15 EEQ28424.1 - 1.8e-186 620.7 0.0 2.7e-186 620.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EEQ28424.1 - 2.5e-25 88.3 0.0 5.7e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EEQ28424.1 - 1.5e-16 60.7 0.1 5.7e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain Sporozoite_P67 PF05642.11 EEQ28425.1 - 0.2 9.7 7.9 0.19 9.8 7.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PRK PF00485.18 EEQ28426.1 - 3.1e-05 23.8 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EEQ28426.1 - 0.00051 19.3 0.0 0.00079 18.7 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 EEQ28426.1 - 0.0007 20.2 0.1 0.0091 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EEQ28426.1 - 0.0015 18.9 0.0 0.0024 18.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EEQ28426.1 - 0.0022 18.1 0.1 0.24 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ28426.1 - 0.0074 16.7 0.0 0.0082 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 EEQ28426.1 - 0.032 14.7 0.1 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 EEQ28426.1 - 0.033 13.1 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Zeta_toxin PF06414.12 EEQ28426.1 - 0.041 13.2 0.3 0.069 12.4 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EEQ28426.1 - 0.048 14.0 0.1 0.087 13.2 0.1 1.3 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 EEQ28426.1 - 0.056 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 EEQ28426.1 - 0.081 12.6 0.0 0.77 9.4 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase DUF2075 PF09848.9 EEQ28426.1 - 0.092 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EEQ28426.1 - 0.094 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EEQ28426.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.20 EEQ28426.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Viral_helicase1 PF01443.18 EEQ28426.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 EEQ28426.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Adhesin_P1 PF03257.13 EEQ28427.1 - 0.034 14.7 2.6 0.044 14.3 2.6 1.2 1 0 0 1 1 1 0 Mycoplasma adhesin P1 Presenilin PF01080.17 EEQ28427.1 - 2.4 6.8 3.4 2.6 6.7 3.4 1.0 1 0 0 1 1 1 0 Presenilin Mur_ligase_M PF08245.12 EEQ28428.1 - 1e-07 32.2 1.0 1.1e-05 25.5 0.2 2.5 2 1 0 2 2 2 2 Mur ligase middle domain Pkinase PF00069.25 EEQ28429.1 - 9.8e-64 215.2 0.0 3.6e-63 213.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28429.1 - 6.1e-44 150.3 0.0 1.6e-43 148.9 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ28429.1 - 0.0026 16.6 0.0 0.0056 15.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase GerD PF17898.1 EEQ28429.1 - 0.13 12.2 1.1 0.4 10.7 1.1 1.8 1 0 0 1 1 1 0 Spore germination GerD central core domain Peptidase_M24 PF00557.24 EEQ28430.1 - 5.4e-44 150.4 0.0 6.7e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 RNA_polI_A34 PF08208.11 EEQ28430.1 - 0.086 12.9 8.1 0.15 12.1 8.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Pectinesterase PF01095.19 EEQ28430.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase Casc1 PF12366.8 EEQ28430.1 - 0.32 10.5 1.4 0.58 9.6 1.4 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 PGA2 PF07543.12 EEQ28430.1 - 0.77 9.7 8.6 1.6 8.7 8.6 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC45 PF02724.14 EEQ28430.1 - 0.81 7.9 7.4 1.1 7.4 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DnaJ PF00226.31 EEQ28431.1 - 1.9e-22 79.2 0.5 3.5e-22 78.3 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.22 EEQ28432.1 - 6.9e-77 258.5 3.7 7.7e-77 258.4 3.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.21 EEQ28433.1 - 6.5e-88 295.8 0.4 5.3e-52 177.6 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EEQ28433.1 - 2.3e-33 114.7 0.0 4.2e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EEQ28433.1 - 1.7e-20 73.6 0.0 3e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EEQ28433.1 - 1.7e-06 27.7 0.1 4e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EEQ28433.1 - 0.002 17.3 0.1 0.0055 15.8 0.1 1.7 1 1 0 1 1 1 1 NAD synthase UQ_con PF00179.26 EEQ28434.1 - 1.4e-42 144.6 0.0 3e-42 143.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme G-patch PF01585.23 EEQ28435.1 - 1.5e-11 44.0 0.5 2.9e-11 43.1 0.5 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EEQ28435.1 - 7.7e-05 22.4 0.1 0.00021 21.0 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mac PF12464.8 EEQ28435.1 - 0.31 11.3 1.6 1.1 9.5 0.4 2.3 2 0 0 2 2 2 0 Maltose acetyltransferase AMP-binding PF00501.28 EEQ28436.1 - 7.9e-89 298.2 0.0 9.3e-89 297.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ28436.1 - 2.7e-13 50.7 0.2 6.3e-13 49.5 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EEQ28436.1 - 0.00015 20.8 0.0 0.0026 16.7 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 EEQ28436.1 - 0.013 15.6 0.1 0.032 14.3 0.1 1.6 1 0 0 1 1 1 0 RTX C-terminal domain Fungal_trans PF04082.18 EEQ28437.1 - 2.4e-15 56.3 0.7 2e-14 53.3 0.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 EEQ28438.1 - 1.2e-17 63.8 0.0 1.8e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Rad10 PF03834.14 EEQ28439.1 - 2.2e-48 163.0 0.0 3.1e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EEQ28439.1 - 0.00062 20.3 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain RRM_1 PF00076.22 EEQ28440.1 - 7.1e-60 198.7 0.0 1.7e-18 66.2 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EEQ28440.1 - 4.1e-06 27.2 6.9 1.8 8.8 0.0 6.2 5 3 2 7 7 7 2 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 EEQ28440.1 - 0.00011 22.0 0.2 0.94 9.3 0.0 3.4 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EEQ28440.1 - 0.0018 18.4 0.0 25 5.1 0.0 3.8 3 0 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 EEQ28440.1 - 0.0054 16.3 0.0 1.8 8.1 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EEQ28440.1 - 0.0076 16.3 1.0 0.5 10.5 0.1 4.0 4 0 0 4 4 4 1 Limkain b1 RRM_occluded PF16842.5 EEQ28440.1 - 0.15 11.9 0.0 1.8 8.5 0.0 2.6 3 0 0 3 3 3 0 Occluded RNA-recognition motif Cyt-b5 PF00173.28 EEQ28441.1 - 3.7e-07 30.2 0.0 4.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.21 EEQ28442.1 - 9.6e-103 344.3 34.0 1.2e-102 344.0 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ28442.1 - 9.4e-16 57.7 38.4 1.3e-15 57.2 38.4 1.1 1 0 0 1 1 1 1 Amino acid permease Cupin_8 PF13621.6 EEQ28443.1 - 8.7e-22 78.0 0.0 1.3e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EEQ28443.1 - 0.0014 18.2 0.0 0.0037 16.8 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 EEQ28443.1 - 0.018 15.4 0.0 0.41 11.1 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 EEQ28443.1 - 0.081 12.6 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Cupin domain DUF5580 PF17743.1 EEQ28443.1 - 0.31 9.5 0.0 0.37 9.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Fungal_trans PF04082.18 EEQ28444.1 - 6.9e-18 64.6 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CK_II_beta PF01214.18 EEQ28445.1 - 9.5e-76 253.7 0.0 2.2e-75 252.5 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.8 EEQ28445.1 - 0.0072 17.3 5.0 0.0072 17.3 5.0 2.4 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal ATP-synt_E PF05680.12 EEQ28445.1 - 0.91 9.9 2.4 44 4.5 0.0 3.1 3 0 0 3 3 3 0 ATP synthase E chain bZIP_2 PF07716.15 EEQ28446.1 - 0.12 12.5 5.7 0.19 11.9 5.7 1.2 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 EEQ28446.1 - 0.13 12.4 8.1 0.21 11.7 8.1 1.2 1 0 0 1 1 1 0 bZIP transcription factor Aminotran_4 PF01063.19 EEQ28448.1 - 6.9e-36 124.2 0.0 8.8e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 EEQ28449.1 - 7.3e-18 64.9 0.0 2.6e-17 63.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28449.1 - 1.7e-07 30.8 0.0 1.3e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase ParcG PF10274.9 EEQ28449.1 - 0.033 14.3 0.6 7.1 6.7 0.1 2.4 2 0 0 2 2 2 0 Parkin co-regulated protein Peptidase_M49 PF03571.15 EEQ28450.1 - 3e-245 814.8 0.0 3.8e-245 814.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 PAD_porph PF04371.15 EEQ28450.1 - 0.11 11.8 0.0 0.42 9.8 0.0 1.9 2 0 0 2 2 2 0 Porphyromonas-type peptidyl-arginine deiminase SNF5 PF04855.12 EEQ28453.1 - 4.3e-83 278.8 0.0 5.5e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EEQ28453.1 - 0.017 14.7 5.7 0.047 13.3 5.7 1.8 1 0 0 1 1 1 0 GATA zinc finger Rubredoxin_2 PF18073.1 EEQ28453.1 - 8 6.3 10.8 1.9 8.3 1.2 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain BHD_1 PF10403.9 EEQ28455.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 WD40 PF00400.32 EEQ28456.1 - 6.1e-21 74.3 24.5 1.7e-05 25.4 0.1 7.4 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ28456.1 - 7.4e-11 42.2 7.0 0.00022 21.5 0.2 4.3 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EEQ28456.1 - 0.0018 18.2 10.8 0.091 12.7 1.7 2.8 1 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term Ank_2 PF12796.7 EEQ28457.1 - 2e-28 98.8 2.5 1.8e-10 41.3 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ28457.1 - 7.7e-24 83.8 5.4 7.5e-09 36.0 0.0 6.0 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ28457.1 - 1.2e-15 56.0 4.3 0.038 14.5 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat GDPD PF03009.17 EEQ28457.1 - 9.2e-14 51.8 0.0 2.1e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.6 EEQ28457.1 - 1.4e-10 41.2 5.5 0.35 11.2 0.0 6.3 3 1 4 7 7 7 4 Ankyrin repeats (many copies) SPX PF03105.19 EEQ28457.1 - 2.4e-09 37.6 13.2 4.6e-05 23.5 0.1 2.8 2 1 1 3 3 3 2 SPX domain Ank PF00023.30 EEQ28457.1 - 1.6e-05 25.1 13.8 0.14 12.6 0.1 6.2 6 1 0 6 6 6 2 Ankyrin repeat zf-C4H2 PF10146.9 EEQ28459.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein MFS_1 PF07690.16 EEQ28460.1 - 1.2e-40 139.5 39.9 1.2e-40 139.5 39.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ28461.1 - 1.7e-102 343.6 18.5 7.3e-102 341.5 18.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ28461.1 - 3.9e-26 91.8 23.6 3.9e-26 91.8 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EEQ28461.1 - 4e-06 25.5 5.0 7.2e-06 24.7 5.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 EEQ28461.1 - 0.86 10.2 6.4 5.5 7.6 5.0 2.9 2 1 1 3 3 3 0 Phage holin family 2 ABC_tran PF00005.27 EEQ28462.1 - 8.5e-47 159.1 0.6 8e-23 81.5 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EEQ28462.1 - 1.2e-21 76.5 6.9 1.2e-21 76.5 6.9 3.2 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 EEQ28462.1 - 1.6e-17 64.3 0.7 0.0021 17.9 0.0 4.8 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ28462.1 - 1.8e-11 43.9 0.4 0.0052 16.3 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EEQ28462.1 - 2.2e-06 28.0 0.0 0.0058 16.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EEQ28462.1 - 5.9e-06 26.3 0.0 0.11 12.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EEQ28462.1 - 6.4e-06 26.8 18.4 0.014 15.9 0.0 5.0 5 0 0 5 5 5 2 AAA domain RsgA_GTPase PF03193.16 EEQ28462.1 - 1.1e-05 25.4 0.9 0.094 12.6 0.1 2.9 2 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EEQ28462.1 - 1.8e-05 25.2 0.3 0.18 12.2 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EEQ28462.1 - 2e-05 24.2 0.3 0.27 11.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 EEQ28462.1 - 9.1e-05 22.3 0.1 0.0099 15.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EEQ28462.1 - 0.0001 22.6 1.2 0.25 11.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EEQ28462.1 - 0.00019 21.6 2.7 0.47 10.6 0.1 3.2 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EEQ28462.1 - 0.00022 21.8 4.9 0.4 11.2 0.0 3.8 5 0 0 5 5 4 2 AAA domain AAA_24 PF13479.6 EEQ28462.1 - 0.00042 20.1 1.1 0.8 9.4 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 EEQ28462.1 - 0.0005 19.9 14.9 0.23 11.1 0.0 5.0 4 1 0 4 4 4 1 AAA ATPase domain AAA PF00004.29 EEQ28462.1 - 0.0029 18.0 0.1 1.2 9.6 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EEQ28462.1 - 0.0037 16.9 0.2 3.3 7.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 EEQ28462.1 - 0.0055 16.8 5.7 1.5 8.8 0.0 4.0 4 1 0 4 4 4 1 Dynamin family NACHT PF05729.12 EEQ28462.1 - 0.0063 16.5 0.4 1.6 8.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 EEQ28462.1 - 0.0085 15.4 1.1 2.4 7.4 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.22 EEQ28462.1 - 0.015 15.7 0.0 7.7 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 EEQ28462.1 - 0.018 14.0 3.7 2 7.3 0.1 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2813 PF11398.8 EEQ28462.1 - 0.021 14.1 0.7 0.14 11.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) Roc PF08477.13 EEQ28462.1 - 0.039 14.2 0.1 8.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EEQ28462.1 - 0.04 13.8 0.1 2.4 8.0 0.1 2.8 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 EEQ28462.1 - 0.042 13.5 0.0 2.8 7.5 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 EEQ28462.1 - 0.047 13.6 0.2 2 8.3 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_7 PF12775.7 EEQ28462.1 - 0.068 12.7 0.0 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Arf PF00025.21 EEQ28462.1 - 0.073 12.5 0.1 2 7.9 0.1 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family MobB PF03205.14 EEQ28462.1 - 0.077 12.9 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EEQ28462.1 - 0.1 12.2 2.5 1.9 8.0 0.4 2.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EEQ28462.1 - 0.11 12.5 1.0 17 5.4 0.0 3.0 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EEQ28462.1 - 0.11 12.5 0.1 12 5.9 0.0 2.7 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Peripla_BP_3 PF13377.6 EEQ28462.1 - 0.12 12.7 0.1 33 4.8 0.0 3.3 3 0 0 3 3 3 0 Periplasmic binding protein-like domain Mg_chelatase PF01078.21 EEQ28462.1 - 0.13 11.7 0.5 51 3.1 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EEQ28462.1 - 0.13 12.3 3.8 13 5.8 0.0 3.5 4 0 0 4 4 3 0 AAA domain DUF1279 PF06916.13 EEQ28465.1 - 4.3e-25 88.1 0.0 5.9e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Cytochrome_cB PF11783.8 EEQ28465.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c bacterial Ribosomal_L3 PF00297.22 EEQ28466.1 - 4.2e-17 62.2 3.7 2.1e-14 53.3 0.6 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 EEQ28467.1 - 7.2e-44 148.3 0.0 8.8e-44 148.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4271 PF14093.6 EEQ28468.1 - 0.0055 16.6 5.5 0.095 12.6 5.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4271) JmjC PF02373.22 EEQ28469.1 - 3.6e-08 33.8 0.9 7.2e-07 29.6 0.9 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EEQ28469.1 - 2.7e-06 27.5 8.4 6.7e-06 26.3 8.4 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 EEQ28469.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Flavoprotein PF02441.19 EEQ28470.1 - 3e-43 147.3 0.0 4.2e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.24 EEQ28471.1 - 6.5e-15 55.1 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Csm1_N PF18504.1 EEQ28472.1 - 1.3 9.4 9.4 0.73 10.2 6.3 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF16 PF01519.16 EEQ28472.1 - 6.8 7.2 10.4 19 5.8 0.0 3.4 1 1 1 3 3 3 0 Protein of unknown function DUF16 CTP_transf_like PF01467.26 EEQ28473.1 - 5.5e-25 88.2 0.6 1.9e-22 80.0 0.0 3.2 3 1 0 3 3 3 2 Cytidylyltransferase-like PRELI PF04707.14 EEQ28475.1 - 1.8e-44 151.3 0.4 2.1e-44 151.1 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family PXA PF02194.15 EEQ28476.1 - 1.3e-30 106.8 0.0 3e-30 105.6 0.0 1.7 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EEQ28476.1 - 4.7e-22 78.7 0.0 1.3e-21 77.3 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EEQ28476.1 - 1.7e-09 37.6 0.0 4.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 PX domain SOG2 PF10428.9 EEQ28476.1 - 2.6 7.2 23.8 0.29 10.3 8.2 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Mito_carr PF00153.27 EEQ28477.1 - 1e-71 236.9 0.8 2.9e-23 81.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ28477.1 - 0.00027 20.2 0.5 0.022 13.9 0.0 3.0 2 1 0 3 3 3 2 Gammaproteobacterial serine protease RRM_1 PF00076.22 EEQ28479.1 - 2e-12 46.7 0.0 2.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEQ28479.1 - 0.00038 20.4 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sedlin_N PF04628.13 EEQ28480.1 - 3.6e-18 65.9 0.0 6.3e-18 65.2 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EEQ28480.1 - 0.019 14.9 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Sybindin-like family Propeptide_C1 PF08127.13 EEQ28480.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C1 propeptide Ribosomal_L18 PF17135.4 EEQ28481.1 - 3e-72 242.0 0.2 3.4e-72 241.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EEQ28481.1 - 0.00079 20.1 0.1 0.0029 18.3 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A AAA_19 PF13245.6 EEQ28481.1 - 0.05 14.0 0.0 0.07 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Aldedh PF00171.22 EEQ28482.1 - 5e-10 38.5 6.8 5e-09 35.2 4.4 2.6 1 1 1 2 2 2 2 Aldehyde dehydrogenase family PCI PF01399.27 EEQ28483.1 - 0.00037 20.9 0.0 0.001 19.5 0.0 1.7 2 0 0 2 2 2 1 PCI domain NifU_N PF01592.16 EEQ28484.1 - 2.4e-41 140.9 0.0 3.3e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EEQ28484.1 - 0.031 14.5 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 TSCPD domain Oxidored_q6 PF01058.22 EEQ28485.1 - 3.3e-22 78.7 0.0 4.7e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit UDG PF03167.19 EEQ28486.1 - 3.7e-22 79.0 0.1 9.3e-22 77.7 0.1 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DUF3381 PF11861.8 EEQ28487.1 - 1.1 9.0 18.2 1.1 9.0 18.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) UCH PF00443.29 EEQ28489.1 - 2.6e-36 125.4 0.0 3.7e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EEQ28489.1 - 9.5e-27 92.5 1.0 1e-24 86.1 0.2 2.7 2 0 0 2 2 2 2 Variant UBP zinc finger zf-UBP PF02148.19 EEQ28489.1 - 1.5e-22 79.6 16.3 1.8e-19 69.8 1.2 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EEQ28489.1 - 2.1e-14 53.9 0.4 1e-11 45.0 0.0 3.4 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EEQ28489.1 - 1.6e-13 50.3 0.0 2e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.6 EEQ28489.1 - 0.017 15.0 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain FtsJ PF01728.19 EEQ28490.1 - 3.5e-55 186.9 0.0 4.2e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EEQ28490.1 - 0.00028 20.7 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ28490.1 - 0.0057 16.5 0.1 0.013 15.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain ATG7_N PF16420.5 EEQ28491.1 - 1.1e-109 366.7 0.0 1.5e-109 366.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EEQ28491.1 - 4.3e-42 144.2 0.0 7e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EEQ28491.1 - 0.078 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EEQ28491.1 - 0.17 11.5 0.0 0.81 9.3 0.0 2.1 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA dCMP_cyt_deam_1 PF00383.23 EEQ28492.1 - 5.3e-27 93.7 2.4 9e-27 92.9 2.4 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EEQ28492.1 - 2.6e-10 40.2 0.2 5.2e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 EEQ28492.1 - 0.031 14.8 0.0 0.23 12.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain CoaE PF01121.20 EEQ28492.1 - 0.036 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase His_biosynth PF00977.21 EEQ28493.1 - 1.4e-45 155.6 0.4 5.4e-45 153.6 0.4 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EEQ28493.1 - 1.9e-24 86.5 0.0 3.1e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EEQ28493.1 - 1.6e-09 37.9 0.0 4e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EEQ28493.1 - 4.1e-09 36.3 0.0 9.5e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EEQ28493.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.17 EEQ28493.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 Peptidase_C26 PF07722.13 EEQ28493.1 - 0.16 11.7 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Peptidase C26 DNA_pol_E_B PF04042.16 EEQ28494.1 - 2.7e-49 167.4 0.1 4e-49 166.8 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.9 EEQ28495.1 - 2.2e-18 65.4 2.7 7.1e-16 57.4 0.4 2.7 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.6 EEQ28495.1 - 5.8e-08 32.9 2.5 0.0061 16.8 1.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 EEQ28495.1 - 0.012 15.7 1.3 0.012 15.7 1.3 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 EEQ28495.1 - 3.2 8.5 8.6 4.1 8.1 1.6 4.2 4 2 2 6 6 6 0 Tetratricopeptide repeat TMPIT PF07851.13 EEQ28495.1 - 4.1 6.6 7.8 4.5 6.4 1.2 2.2 1 1 1 2 2 2 0 TMPIT-like protein TPR_1 PF00515.28 EEQ28495.1 - 6.4 6.8 5.9 2.6 8.0 1.7 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Yippee-Mis18 PF03226.14 EEQ28496.1 - 6.8e-22 77.7 0.0 9.6e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transp_Tc5_C PF04236.15 EEQ28496.1 - 0.0099 16.2 0.1 0.52 10.7 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase C-terminal domain RIG-I_C-RD PF11648.8 EEQ28496.1 - 0.042 14.1 1.6 0.37 11.0 1.6 2.1 1 1 0 1 1 1 0 C-terminal domain of RIG-I Thioredoxin PF00085.20 EEQ28497.1 - 7.1e-66 218.7 6.4 7.3e-31 106.2 0.1 4.4 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.6 EEQ28497.1 - 1.8e-47 161.7 2.3 4.1e-37 127.9 0.6 3.6 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EEQ28497.1 - 1.3e-08 35.2 1.4 0.0048 17.3 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EEQ28497.1 - 2.7e-08 33.9 0.0 0.0051 17.0 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Calsequestrin PF01216.17 EEQ28497.1 - 4.1e-08 32.7 3.3 1.4e-07 30.9 3.3 1.9 1 1 0 1 1 1 1 Calsequestrin OST3_OST6 PF04756.13 EEQ28497.1 - 4.6e-08 32.8 0.6 0.0085 15.5 0.0 3.4 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EEQ28497.1 - 5e-07 29.9 0.0 0.1 12.9 0.0 4.1 4 1 1 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.21 EEQ28497.1 - 6e-06 26.2 0.2 0.033 14.1 0.1 2.7 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.13 EEQ28497.1 - 2.1e-05 24.6 0.6 1.7 8.8 0.0 4.5 4 0 0 4 4 4 1 ERp29, N-terminal domain Redoxin PF08534.10 EEQ28497.1 - 0.0075 16.0 1.1 1.7 8.4 0.0 2.8 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.6 EEQ28497.1 - 0.52 10.5 5.0 14 5.8 0.1 3.8 4 0 0 4 4 4 0 Thioredoxin Med14 PF08638.11 EEQ28498.1 - 9.5e-45 152.4 0.0 2.2e-44 151.1 0.0 1.6 2 0 0 2 2 2 1 Mediator complex subunit MED14 DWNN PF08783.11 EEQ28499.1 - 1.6e-33 114.8 0.1 3.2e-33 113.8 0.1 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EEQ28499.1 - 6.2e-09 35.5 5.0 6.2e-09 35.5 5.0 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EEQ28499.1 - 0.00022 21.1 1.0 0.00022 21.1 1.0 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EEQ28499.1 - 0.029 14.3 0.2 0.08 12.9 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-RING_2 PF13639.6 EEQ28499.1 - 0.042 14.2 6.5 0.098 13.0 6.5 1.6 1 0 0 1 1 1 0 Ring finger domain FYVE_2 PF02318.16 EEQ28499.1 - 0.13 12.5 1.6 0.34 11.1 1.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DUF1272 PF06906.11 EEQ28499.1 - 0.14 12.3 5.2 0.39 10.8 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 EEQ28499.1 - 0.32 10.8 6.0 0.68 9.8 6.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EEQ28499.1 - 0.38 10.9 5.9 1.2 9.4 5.9 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SPX PF03105.19 EEQ28499.1 - 0.97 9.3 16.1 0.51 10.2 8.7 2.3 2 0 0 2 2 2 0 SPX domain zf-C3HC4 PF00097.25 EEQ28499.1 - 2 8.4 8.0 4.6 7.2 8.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ28499.1 - 5 7.1 15.9 0.094 12.6 8.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ndc1_Nup PF09531.10 EEQ28499.1 - 8.8 4.9 7.9 14 4.2 7.9 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nucleoporin_C PF03177.14 EEQ28500.1 - 2.6e-172 574.7 2.3 3.1e-172 574.4 2.3 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EEQ28500.1 - 5e-57 193.6 0.2 7.2e-57 193.1 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like HABP4_PAI-RBP1 PF04774.15 EEQ28501.1 - 0.0077 17.1 1.9 0.012 16.5 1.9 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family OST3_OST6 PF04756.13 EEQ28502.1 - 5.3e-102 341.1 0.0 6.7e-102 340.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EEQ28502.1 - 0.00028 20.8 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HXXEE PF13787.6 EEQ28502.1 - 0.0028 18.4 0.6 0.0077 17.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function with HXXEE motif DUF2613 PF11021.8 EEQ28502.1 - 0.36 11.0 0.0 0.36 11.0 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) GAS PF13851.6 EEQ28503.1 - 0.013 14.8 16.4 0.056 12.8 16.3 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EEQ28503.1 - 0.054 13.1 16.8 0.086 12.4 13.5 2.1 1 1 1 2 2 2 0 Intermediate filament protein HALZ PF02183.18 EEQ28503.1 - 0.17 12.1 4.0 4 7.8 0.5 3.4 1 1 2 3 3 3 0 Homeobox associated leucine zipper DUF2730 PF10805.8 EEQ28503.1 - 0.24 11.5 4.4 0.27 11.4 1.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) EzrA PF06160.12 EEQ28503.1 - 0.44 8.6 15.4 1.2 7.2 15.4 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.7 EEQ28503.1 - 1.1 9.4 17.0 2.4 8.3 15.3 2.5 1 1 0 1 1 1 0 Tropomyosin like CorA PF01544.18 EEQ28503.1 - 5.3 6.3 13.0 1.7 7.9 9.3 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Cnn_1N PF07989.11 EEQ28503.1 - 6.1 7.1 19.9 0.15 12.3 1.5 3.5 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 DUF724 PF05266.14 EEQ28503.1 - 7.1 6.4 19.6 0.98 9.2 9.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Complex1_LYR PF05347.15 EEQ28504.1 - 0.03 14.4 0.3 0.054 13.6 0.3 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEQ28504.1 - 0.12 13.2 0.0 0.2 12.4 0.0 1.5 1 1 0 1 1 1 0 Complex1_LYR-like zinc_ribbon_6 PF14599.6 EEQ28505.1 - 1.9e-25 88.6 0.6 1.9e-25 88.6 0.6 3.5 5 0 0 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 EEQ28505.1 - 2.2e-18 66.5 17.3 2.2e-18 66.5 17.3 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EEQ28505.1 - 4.5e-08 33.3 9.1 4.5e-08 33.3 9.1 5.1 2 1 4 6 6 6 1 Ring finger domain zf-RING_5 PF14634.6 EEQ28505.1 - 3.9e-06 26.7 7.5 3.9e-06 26.7 7.5 6.5 5 2 1 6 6 6 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EEQ28505.1 - 6.1e-06 26.0 6.2 6.1e-06 26.0 6.2 5.1 3 1 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ28505.1 - 0.00011 22.2 6.2 0.00011 22.2 6.2 3.9 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EEQ28505.1 - 0.00013 21.7 8.9 0.00013 21.7 8.9 5.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 EEQ28505.1 - 0.0076 16.2 7.2 0.0076 16.2 7.2 5.8 5 2 2 7 7 7 1 Prokaryotic RING finger family 1 Rrn6 PF10214.9 EEQ28506.1 - 1.1e-211 705.7 0.3 1.3e-211 705.5 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 EEQ28507.1 - 2.3e-24 85.4 0.1 1.2e-23 83.1 0.0 2.3 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF334 PF03904.13 EEQ28507.1 - 0.38 10.2 8.6 0.54 9.8 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) ERM PF00769.19 EEQ28507.1 - 1.2 8.9 20.1 1.9 8.2 20.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.15 EEQ28507.1 - 2.3 7.7 9.7 3.3 7.2 9.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EEQ28507.1 - 3.4 6.7 14.9 4.7 6.2 14.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ku_C PF03730.14 EEQ28507.1 - 3.6 8.4 6.4 1.2 9.9 2.2 2.0 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm LMBR1 PF04791.16 EEQ28507.1 - 4.3 6.1 4.0 4.7 6.0 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 EEQ28507.1 - 8.8 5.6 11.3 13 5.1 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.32 EEQ28508.1 - 8.4e-15 54.9 8.2 0.018 15.9 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Ribosomal_L32p PF01783.23 EEQ28508.1 - 1.5e-13 50.8 6.4 2.4e-13 50.1 6.4 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family ANAPC4_WD40 PF12894.7 EEQ28508.1 - 1e-07 32.1 0.0 0.0035 17.6 0.0 3.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zinc-ribbons_6 PF07191.12 EEQ28508.1 - 0.033 14.2 0.6 0.057 13.4 0.6 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-ribbon_3 PF13248.6 EEQ28508.1 - 0.033 13.6 0.8 0.06 12.8 0.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-IS66 PF13005.7 EEQ28508.1 - 0.11 13.0 1.5 1.9 9.0 0.0 2.3 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 Septin PF00735.18 EEQ28509.1 - 5.5e-112 373.6 0.4 6.5e-112 373.4 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EEQ28509.1 - 6.1e-08 32.7 0.0 1.2e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EEQ28509.1 - 4.8e-06 26.1 0.0 8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EEQ28509.1 - 6.6e-05 22.9 0.6 0.00028 20.9 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EEQ28509.1 - 0.00031 20.8 0.3 0.99 9.4 0.1 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 EEQ28509.1 - 0.00033 20.3 0.6 0.015 14.8 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 EEQ28509.1 - 0.0033 16.6 0.1 0.0058 15.8 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 EEQ28509.1 - 0.0047 16.5 0.1 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EEQ28509.1 - 0.0053 17.2 0.0 0.012 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ28509.1 - 0.0096 16.2 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EEQ28509.1 - 0.011 16.3 0.2 0.024 15.2 0.2 1.6 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 EEQ28509.1 - 0.049 12.8 0.6 0.4 9.8 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit Roc PF08477.13 EEQ28509.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EEQ28509.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 EEQ28509.1 - 0.087 12.2 0.1 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region T2SSE PF00437.20 EEQ28509.1 - 0.09 11.8 0.1 0.27 10.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 EEQ28509.1 - 0.12 12.2 0.1 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Guanylate_kin PF00625.21 EEQ28510.1 - 9.8e-59 198.1 0.0 2.6e-46 157.6 0.0 2.0 1 1 1 2 2 2 2 Guanylate kinase AAA_16 PF13191.6 EEQ28510.1 - 2.5e-05 24.7 0.2 5.4e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EEQ28510.1 - 7.9e-05 23.2 0.5 0.00045 20.8 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ28510.1 - 0.00014 22.0 0.3 0.0085 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ28510.1 - 0.00023 21.4 0.1 0.00058 20.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEQ28510.1 - 0.00035 20.3 0.0 0.00073 19.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EEQ28510.1 - 0.00043 20.4 0.0 0.0022 18.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EEQ28510.1 - 0.00082 19.6 0.1 0.0024 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EEQ28510.1 - 0.0012 19.4 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EEQ28510.1 - 0.0019 18.2 0.0 0.0036 17.2 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 EEQ28510.1 - 0.0062 16.1 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 EEQ28510.1 - 0.009 16.4 0.1 0.12 12.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EEQ28510.1 - 0.0094 15.7 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 EEQ28510.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EEQ28510.1 - 0.012 16.0 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EEQ28510.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EEQ28510.1 - 0.014 14.7 0.1 0.071 12.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 EEQ28510.1 - 0.022 14.5 0.1 0.12 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EEQ28510.1 - 0.026 14.5 0.1 0.15 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EEQ28510.1 - 0.043 12.9 0.0 0.097 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 EEQ28510.1 - 0.056 13.0 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EEQ28510.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 NTPase Adeno_IVa2 PF02456.15 EEQ28510.1 - 0.065 12.0 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Rad17 PF03215.15 EEQ28510.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 EEQ28510.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EEQ28510.1 - 0.093 13.2 0.4 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EEQ28510.1 - 0.1 13.1 0.1 0.3 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EEQ28510.1 - 0.11 12.4 0.0 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3774 PF12609.8 EEQ28510.1 - 0.12 13.5 0.0 0.19 12.8 0.0 1.4 1 0 0 1 1 1 0 Wound-induced protein dNK PF01712.19 EEQ28510.1 - 0.13 12.2 0.1 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase GRAB PF10375.9 EEQ28511.1 - 5.1e-08 32.5 0.2 1.1e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain LMP PF04778.12 EEQ28511.1 - 0.0001 22.3 30.8 0.021 14.8 3.3 4.5 2 1 2 4 4 4 3 LMP repeated region DUF3921 PF13060.6 EEQ28511.1 - 0.018 15.0 0.1 0.068 13.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) Golgin_A5 PF09787.9 EEQ28511.1 - 0.039 13.4 61.2 1.1 8.6 10.5 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 FliJ PF02050.16 EEQ28511.1 - 1.2 9.3 42.0 0.74 10.0 14.5 3.7 1 1 2 3 3 3 0 Flagellar FliJ protein HALZ PF02183.18 EEQ28511.1 - 6 7.2 15.1 5.9 7.2 0.0 5.6 5 0 0 5 5 5 0 Homeobox associated leucine zipper FAM184 PF15665.5 EEQ28511.1 - 9 6.0 56.5 0.15 11.9 12.0 3.6 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B NFACT-R_1 PF05670.13 EEQ28512.1 - 4.3e-09 37.0 0.1 7.3e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain DAO PF01266.24 EEQ28515.1 - 5.7e-51 174.2 0.0 7.7e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EEQ28515.1 - 1.4e-43 147.7 0.1 2.3e-43 147.1 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EEQ28515.1 - 5.2e-08 32.4 0.0 1.1e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EEQ28515.1 - 1.6e-06 27.8 0.2 0.00018 21.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ28515.1 - 0.00043 19.6 0.1 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EEQ28515.1 - 0.0035 16.5 0.2 0.028 13.5 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 EEQ28515.1 - 0.0047 16.8 0.2 0.0088 15.9 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EEQ28515.1 - 0.013 15.7 0.1 0.046 14.0 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EEQ28515.1 - 0.049 12.3 0.4 0.081 11.6 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EEQ28515.1 - 0.053 12.8 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 EEQ28515.1 - 0.057 12.7 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ28515.1 - 0.088 13.4 0.1 0.32 11.6 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ28515.1 - 0.096 11.7 0.0 1.3 8.0 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein p450 PF00067.22 EEQ28516.1 - 1.1e-64 218.9 0.0 1.2e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DASH_Dad2 PF08654.10 EEQ28517.1 - 2.8e-12 46.9 5.6 5.9e-10 39.5 1.3 2.1 1 1 1 2 2 2 2 DASH complex subunit Dad2 BBS2_C PF14782.6 EEQ28517.1 - 0.064 12.0 0.4 0.067 12.0 0.4 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal FliD_N PF02465.18 EEQ28517.1 - 0.092 13.4 3.6 0.13 13.0 3.6 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus APG6_N PF17675.1 EEQ28517.1 - 0.35 11.4 5.2 0.52 10.8 5.2 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Shugoshin_N PF07558.11 EEQ28518.1 - 5.3e-19 67.8 2.0 1.1e-18 66.7 2.0 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EEQ28518.1 - 1.7e-10 40.5 7.1 1.7e-10 40.5 7.1 3.1 4 0 0 4 4 4 1 Shugoshin C terminus TetR_C_14 PF17754.1 EEQ28518.1 - 0.055 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 MftR C-terminal domain PPI_Ypi1 PF07491.11 EEQ28519.1 - 1.3e-25 89.0 1.6 1.3e-25 89.0 1.6 2.1 1 1 1 2 2 2 1 Protein phosphatase inhibitor AF-4 PF05110.13 EEQ28519.1 - 0.0021 16.3 5.1 0.0025 16.0 5.1 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein ALAD PF00490.21 EEQ28520.1 - 1.7e-121 405.3 0.0 2e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Mac_assoc PF16628.5 EEQ28521.1 - 2e-66 223.8 16.4 2e-66 223.8 16.4 2.8 2 1 0 2 2 2 1 Unstructured region on maltose acetyltransferase Hexapep PF00132.24 EEQ28521.1 - 7.8e-12 44.4 6.2 1e-07 31.4 0.3 3.5 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EEQ28521.1 - 2.6e-10 40.4 0.0 6.5e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 EEQ28521.1 - 4e-10 39.6 8.6 7.2e-10 38.8 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.6 EEQ28521.1 - 6.6e-07 29.0 5.5 8e-06 25.5 0.4 3.1 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase FAD_binding_3 PF01494.19 EEQ28523.1 - 9.2e-20 71.2 0.0 2.7e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EEQ28523.1 - 1.5e-06 28.4 1.7 4.3e-06 26.9 1.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ28523.1 - 1.8e-06 27.4 0.8 6.2e-05 22.4 1.7 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ28523.1 - 2.9e-06 27.1 7.1 0.015 14.9 5.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EEQ28523.1 - 2.1e-05 23.8 5.8 3.6e-05 23.0 5.8 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EEQ28523.1 - 0.00018 20.4 0.7 0.0065 15.2 2.2 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EEQ28523.1 - 0.00039 19.6 1.6 0.00052 19.2 1.6 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EEQ28523.1 - 0.00061 19.3 4.0 0.00088 18.7 4.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EEQ28523.1 - 0.0017 18.9 1.5 0.029 14.9 1.8 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ28523.1 - 0.0053 15.9 0.3 0.024 13.7 0.3 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 EEQ28523.1 - 0.0055 16.1 0.4 0.38 10.0 0.4 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EEQ28523.1 - 0.0067 15.3 1.2 1.1 8.0 1.5 2.3 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 EEQ28523.1 - 0.012 14.8 0.7 0.021 14.1 0.7 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EEQ28523.1 - 0.085 12.7 2.8 0.15 11.9 2.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EEQ28523.1 - 0.086 12.7 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain AlaDh_PNT_C PF01262.21 EEQ28523.1 - 0.24 10.7 1.5 0.45 9.8 1.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 EEQ28523.1 - 0.28 9.9 0.7 0.93 8.2 0.3 2.0 3 0 0 3 3 3 0 MCRA family Pyr_redox_3 PF13738.6 EEQ28523.1 - 0.74 9.0 4.3 1.2 8.3 4.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CRM1_C PF08767.11 EEQ28524.1 - 6.7e-121 403.4 5.3 6.7e-121 403.4 5.3 3.7 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EEQ28524.1 - 1.9e-41 141.6 6.6 1.9e-41 141.6 6.6 3.2 3 1 1 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EEQ28524.1 - 9.3e-34 114.9 4.1 4.9e-33 112.6 4.1 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EEQ28524.1 - 2.9e-29 100.9 0.7 2.9e-29 100.9 0.7 2.8 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EEQ28524.1 - 6.3e-20 70.4 1.3 1.4e-19 69.2 1.3 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat DUF3385 PF11865.8 EEQ28524.1 - 0.0044 16.9 0.3 0.3 11.0 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) IBN_N PF03810.19 EEQ28524.1 - 0.03 14.2 0.1 0.41 10.6 0.1 2.8 1 1 0 1 1 1 0 Importin-beta N-terminal domain CIAPIN1 PF05093.13 EEQ28525.1 - 1.4e-42 144.3 3.8 2.4e-42 143.5 3.8 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EEQ28525.1 - 2.1e-35 121.8 0.6 6.7e-35 120.2 0.1 1.9 2 0 0 2 2 2 1 Fe-S cluster assembly protein DRE2 N-terminus Rft-1 PF04506.13 EEQ28526.1 - 7.6e-131 437.3 15.6 9.8e-131 437.0 15.6 1.0 1 0 0 1 1 1 1 Rft protein Rep_fac-A_C PF08646.10 EEQ28527.1 - 1.5e-46 157.8 6.6 3.3e-45 153.4 3.8 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EEQ28527.1 - 2.7e-35 120.2 0.2 6.9e-35 118.9 0.1 1.8 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EEQ28527.1 - 1.8e-20 72.8 0.0 3.9e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EEQ28527.1 - 3.6e-12 46.1 0.3 7.2e-08 32.3 0.0 4.1 3 1 1 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EEQ28527.1 - 0.0015 18.2 0.6 0.019 14.7 0.1 2.6 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 EEQ28527.1 - 0.038 14.3 0.5 0.32 11.3 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF223 DUF4503 PF14951.6 EEQ28527.1 - 0.13 10.7 0.2 0.2 10.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) DUF2293 PF10056.9 EEQ28528.1 - 1.1e-28 99.2 1.3 2.2e-28 98.3 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Edc3_linker PF16598.5 EEQ28528.1 - 1.3 9.8 8.3 3.3 8.4 1.0 3.5 3 0 0 3 3 3 0 Linker region of enhancer of mRNA-decapping protein 3 MHYT PF03707.16 EEQ28529.1 - 1.5e-18 66.7 20.1 3.6e-10 39.8 1.5 4.4 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat DUF4271 PF14093.6 EEQ28529.1 - 1.2 9.0 11.5 0.15 12.0 5.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) HMA PF00403.26 EEQ28530.1 - 3.9e-16 59.2 0.7 4.6e-16 59.0 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Vps4_C PF09336.10 EEQ28530.1 - 0.0081 16.1 0.1 0.01 15.8 0.1 1.3 1 1 0 1 1 1 1 Vps4 C terminal oligomerisation domain Fer2_BFD PF04324.15 EEQ28530.1 - 0.021 15.2 0.3 0.37 11.2 0.1 2.2 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain PMSR PF01625.21 EEQ28530.1 - 0.11 12.7 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase Tcp11 PF05794.13 EEQ28531.1 - 5.8e-107 358.5 0.8 5.8e-107 358.5 0.8 2.4 3 0 0 3 3 3 1 T-complex protein 11 COS PF18568.1 EEQ28531.1 - 0.52 10.3 2.4 31 4.6 0.2 3.0 2 0 0 2 2 2 0 TRIM C-terminal subgroup One Signature domain PXA PF02194.15 EEQ28532.1 - 1.1e-45 155.8 0.2 7.3e-45 153.2 0.1 2.0 2 0 0 2 2 2 1 PXA domain AP_endonuc_2 PF01261.24 EEQ28532.1 - 0.0074 15.7 0.4 0.11 11.9 0.1 2.1 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF1670 PF07900.11 EEQ28532.1 - 0.041 13.2 0.0 0.15 11.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1670) Nexin_C PF08628.12 EEQ28533.1 - 1.9e-27 96.1 0.3 4.3e-27 94.9 0.0 1.8 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EEQ28533.1 - 4.4e-20 71.8 0.1 8.6e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 PX domain WD40 PF00400.32 EEQ28535.1 - 9e-18 64.3 6.9 0.002 18.9 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ28535.1 - 4.3e-07 30.1 0.0 0.028 14.7 0.0 4.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ28535.1 - 0.007 15.4 0.4 0.16 10.9 0.0 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEQ28535.1 - 0.068 11.8 1.6 3.4 6.2 0.2 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 tRNA-synt_1g PF09334.11 EEQ28536.1 - 1.5e-149 498.1 0.0 2.3e-149 497.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EEQ28536.1 - 3.3e-07 28.9 0.0 4.8e-05 21.8 0.0 3.3 3 1 1 4 4 4 2 tRNA synthetases class I (I, L, M and V) Laminin_EGF PF00053.24 EEQ28536.1 - 0.34 11.1 3.8 0.6 10.3 3.8 1.4 1 0 0 1 1 1 0 Laminin EGF domain PepSY PF03413.19 EEQ28536.1 - 0.63 10.7 4.1 21 5.8 0.0 2.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Yae1_N PF09811.9 EEQ28537.1 - 3.3e-05 23.5 1.2 6e-05 22.7 1.2 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Spt20 PF12090.8 EEQ28538.1 - 4.3e-57 193.4 0.7 6.1e-57 192.9 0.7 1.2 1 0 0 1 1 1 1 Spt20 family Fungal_lectin_2 PF18647.1 EEQ28539.1 - 2.7e-40 136.9 0.5 8.4e-40 135.4 0.5 1.9 2 0 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin LysM PF01476.20 EEQ28540.1 - 1.6e-08 34.4 0.0 0.00016 21.7 0.0 3.2 3 0 0 3 3 3 2 LysM domain HTH_Tnp_1 PF01527.20 EEQ28540.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Transposase K_channel_TID PF07941.11 EEQ28542.1 - 1.5 9.3 5.9 4.3 7.9 5.9 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Hexapep PF00132.24 EEQ28543.1 - 2.2e-06 27.2 2.5 0.024 14.4 0.4 3.8 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EEQ28543.1 - 2.3e-05 23.6 0.3 3.9e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 EEQ28543.1 - 0.0054 16.3 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EEQ28543.1 - 0.029 14.7 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF4954 PF16314.5 EEQ28543.1 - 0.036 12.2 0.1 0.052 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) HS1_rep PF02218.15 EEQ28544.1 - 0.12 12.8 0.4 0.22 11.9 0.4 1.4 1 0 0 1 1 1 0 Repeat in HS1/Cortactin SCIMP PF15050.6 EEQ28547.1 - 6.6 7.2 6.4 9 6.8 0.7 3.0 2 0 0 2 2 2 0 SCIMP protein ELO PF01151.18 EEQ28548.1 - 1.9e-57 194.7 4.4 1.2e-44 152.8 1.4 2.1 2 0 0 2 2 2 2 GNS1/SUR4 family DUF4222 PF13973.6 EEQ28550.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4222) Fungal_trans_2 PF11951.8 EEQ28551.1 - 0.00078 18.4 2.4 0.0014 17.5 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ28551.1 - 0.0035 17.4 2.1 0.0091 16.1 2.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1500 PF07389.12 EEQ28551.1 - 0.074 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) APH PF01636.23 EEQ28553.1 - 1.6e-14 54.4 0.0 1.3e-13 51.5 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ28553.1 - 0.0003 20.4 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase HNH_2 PF13391.6 EEQ28553.1 - 0.13 12.4 0.1 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 HNH endonuclease DUF1679 PF07914.11 EEQ28553.1 - 0.2 10.5 0.1 0.68 8.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Glyco_hydro_61 PF03443.14 EEQ28554.1 - 0.052 13.5 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 BNR PF02012.20 EEQ28554.1 - 0.1 12.6 1.2 0.23 11.6 0.2 2.2 2 0 0 2 2 2 0 BNR/Asp-box repeat TruD PF01142.18 EEQ28555.1 - 5.5e-56 190.2 0.0 1.2e-54 185.7 0.0 2.4 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Amelin PF05111.12 EEQ28556.1 - 0.19 10.8 3.4 0.29 10.2 3.4 1.3 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) P53_TAD PF08563.11 EEQ28556.1 - 0.19 11.2 0.8 0.39 10.3 0.8 1.5 1 0 0 1 1 1 0 P53 transactivation motif RPE65 PF03055.15 EEQ28557.1 - 4.5e-114 382.2 0.0 5.1e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SRPRB PF09439.10 EEQ28557.1 - 0.18 11.2 0.0 1.9 7.9 0.0 2.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF2293 PF10056.9 EEQ28558.1 - 2.3e-28 98.3 0.2 2.3e-28 98.3 0.2 2.0 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2293) DUF3754 PF12576.8 EEQ28558.1 - 0.064 13.2 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) APH PF01636.23 EEQ28559.1 - 2.2e-12 47.5 0.0 4.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ28559.1 - 0.035 13.0 0.0 0.097 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.14 EEQ28559.1 - 0.099 12.0 0.0 4 6.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEQ28559.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mtc PF03820.17 EEQ28561.1 - 7.9e-119 396.3 0.0 8.9e-119 396.2 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.25 EEQ28563.1 - 1.9e-49 168.4 0.0 9.7e-49 166.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28563.1 - 1.4e-19 70.4 0.0 5.1e-19 68.6 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Cytokin-bind PF09265.10 EEQ28563.1 - 0.13 11.6 0.2 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding YqgC PF17430.2 EEQ28563.1 - 0.15 12.1 1.3 2.4 8.3 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized YqgC-like Barwin PF00967.17 EEQ28564.1 - 0.011 15.6 1.2 0.016 15.0 0.8 1.4 1 1 0 1 1 1 0 Barwin family ToxB_N PF18224.1 EEQ28564.1 - 0.012 15.6 2.8 0.14 12.1 0.3 2.3 2 0 0 2 2 2 0 ToxB N-terminal domain DPBB_1 PF03330.18 EEQ28564.1 - 0.024 14.9 0.7 0.064 13.5 0.7 1.8 1 1 0 1 1 1 0 Lytic transglycolase ChiW_Ig_like PF18683.1 EEQ28564.1 - 0.32 11.2 1.8 0.54 10.5 0.3 1.8 1 1 1 2 2 2 0 Chitinase W immunoglobulin-like domain FAD_binding_4 PF01565.23 EEQ28565.1 - 2.4e-24 85.6 1.4 4.4e-24 84.8 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EEQ28565.1 - 1.7e-13 50.5 0.0 4.9e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like CPSF73-100_C PF11718.8 EEQ28566.1 - 2e-79 266.2 0.0 3.2e-79 265.5 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EEQ28566.1 - 3.4e-31 107.8 0.0 1e-30 106.3 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EEQ28566.1 - 2.7e-22 79.7 0.1 4.7e-22 79.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EEQ28566.1 - 1.6e-16 60.4 0.1 2.6e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EEQ28566.1 - 5.2e-12 45.5 0.1 1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EEQ28566.1 - 0.0001 21.9 0.1 0.00022 20.8 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EEQ28566.1 - 0.00021 21.2 0.0 0.00093 19.1 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.14 EEQ28567.1 - 2.9e-24 86.3 7.5 5.6e-23 82.1 7.5 2.6 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Aminotran_3 PF00202.21 EEQ28568.1 - 5.6e-82 275.6 0.0 7.2e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.18 EEQ28569.1 - 6.1e-15 55.0 0.1 1.1e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ28569.1 - 5.7e-11 42.4 3.6 1.1e-10 41.4 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP19 PF01922.17 EEQ28570.1 - 6.8e-33 113.5 0.0 2.3e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 SRP19 protein TCTP PF00838.17 EEQ28571.1 - 1.3e-67 227.3 3.3 1.4e-67 227.2 3.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein AAA_18 PF13238.6 EEQ28571.1 - 0.041 14.4 0.1 0.055 14.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain SUB1_ProdP9 PF18213.1 EEQ28571.1 - 0.048 13.5 2.3 1.2 9.0 0.5 2.3 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 Put_Phosphatase PF06888.12 EEQ28571.1 - 0.064 12.6 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative Phosphatase GMC_oxred_N PF00732.19 EEQ28573.1 - 2.1e-46 158.6 0.5 3.4e-46 158.0 0.5 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EEQ28573.1 - 2.7e-29 102.5 0.9 6.9e-29 101.2 0.1 2.1 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EEQ28573.1 - 8.2e-07 28.4 0.1 3.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EEQ28573.1 - 7.8e-05 22.0 0.3 0.00019 20.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEQ28573.1 - 0.00084 18.6 0.1 0.009 15.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EEQ28573.1 - 0.0033 16.7 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EEQ28573.1 - 0.02 14.2 0.5 0.032 13.6 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ28573.1 - 0.029 14.6 1.7 0.12 12.7 0.7 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trypan_PARP PF05887.11 EEQ28574.1 - 0.027 14.4 3.3 0.042 13.8 3.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FA_hydroxylase PF04116.13 EEQ28575.1 - 4.5e-15 56.2 10.5 4.5e-15 56.2 10.5 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cation_ATPase_C PF00689.21 EEQ28575.1 - 0.014 15.1 0.2 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus UNC-79 PF14776.6 EEQ28575.1 - 0.033 13.0 0.0 0.047 12.4 0.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 MmgE_PrpD PF03972.14 EEQ28575.1 - 0.15 10.6 0.1 0.25 9.8 0.1 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Aldo_ket_red PF00248.21 EEQ28576.1 - 5.6e-64 216.2 0.0 6.3e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Kelch_5 PF13854.6 EEQ28577.1 - 4.7e-12 45.6 0.7 6e-11 42.1 0.6 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 EEQ28577.1 - 4e-05 23.1 4.9 0.17 11.5 0.5 4.0 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 EEQ28577.1 - 5.3e-05 23.1 1.9 0.0016 18.4 0.1 3.6 2 2 1 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EEQ28577.1 - 0.00052 20.2 1.7 0.032 14.5 0.3 3.7 3 1 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 EEQ28577.1 - 0.046 14.0 0.3 1.6 9.1 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain BatA PF07584.11 EEQ28577.1 - 0.1 13.0 0.2 0.19 12.1 0.2 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Arf PF00025.21 EEQ28583.1 - 8.6e-41 139.3 0.0 1.3e-26 93.2 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EEQ28583.1 - 3.5e-11 43.4 0.0 1.1e-10 41.8 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EEQ28583.1 - 1.4e-10 40.9 0.0 0.00013 21.2 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EEQ28583.1 - 2.2e-07 30.6 0.0 0.0013 18.3 0.0 2.4 2 1 0 2 2 2 2 Ras family MMR_HSR1 PF01926.23 EEQ28583.1 - 1.4e-06 28.3 0.0 9.1e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEQ28583.1 - 4.1e-06 26.3 0.0 4.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EEQ28583.1 - 5.1e-06 26.2 0.0 0.00014 21.5 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EEQ28583.1 - 1.2e-05 24.9 0.0 0.00012 21.6 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF4630 PF15443.6 EEQ28583.1 - 0.0088 16.2 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4630) AAA_24 PF13479.6 EEQ28583.1 - 0.043 13.5 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EEQ28583.1 - 0.049 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EEQ28583.1 - 0.05 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 EEQ28583.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EEQ28583.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B PIGA PF08288.12 EEQ28584.1 - 8.3e-46 154.5 1.5 8.3e-46 154.5 1.5 1.8 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EEQ28584.1 - 1.6e-27 96.5 0.3 2.5e-27 95.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EEQ28584.1 - 4.6e-26 91.4 0.0 6.9e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEQ28584.1 - 3.5e-23 82.5 0.1 6.5e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EEQ28584.1 - 2.1e-11 44.6 0.0 3.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EEQ28584.1 - 5.6e-06 26.4 0.1 1.2e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EEQ28584.1 - 0.00051 20.4 0.0 0.0021 18.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 DEAD PF00270.29 EEQ28585.1 - 5.8e-34 117.4 0.0 8.3e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ28585.1 - 5.2e-19 68.6 0.0 3.5e-18 66.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ28585.1 - 4.4e-06 26.8 0.0 6.2e-05 23.1 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ANAPC1 PF12859.7 EEQ28585.1 - 0.94 10.0 17.0 0.12 12.9 6.4 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 1 Prp18 PF02840.15 EEQ28586.1 - 2e-55 186.8 0.0 2e-55 186.8 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EEQ28586.1 - 2.1e-10 40.0 3.3 2.1e-10 40.0 3.3 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.10 EEQ28586.1 - 4.2 6.6 25.0 7.2 5.9 25.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDRGK PF09756.9 EEQ28586.1 - 5.9 6.4 26.8 14 5.2 26.8 1.7 1 0 0 1 1 1 0 DDRGK domain SAP18 PF06487.12 EEQ28587.1 - 1.6e-49 167.7 0.0 2e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) NDUF_B4 PF07225.12 EEQ28588.1 - 5.6e-05 23.0 0.0 6.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) COX7a PF02238.15 EEQ28588.1 - 0.094 13.1 1.2 0.13 12.7 1.2 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII Methyltr_RsmB-F PF01189.17 EEQ28589.1 - 4.4e-18 65.7 0.0 2.2e-09 37.3 0.0 2.9 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F Acetyltransf_10 PF13673.7 EEQ28590.1 - 2.7e-10 40.2 0.0 1.1e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ28590.1 - 2e-09 37.7 0.2 2.9e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ28590.1 - 4.1e-09 36.7 0.0 7.5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EEQ28590.1 - 1.4e-07 32.1 0.0 2.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ28590.1 - 0.00016 21.6 0.0 0.00035 20.5 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EEQ28590.1 - 0.0011 19.0 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EEQ28590.1 - 0.007 17.0 0.1 0.0094 16.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEQ28590.1 - 0.032 14.3 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FYVE PF01363.21 EEQ28591.1 - 1.9e-14 53.5 5.5 2.9e-14 53.0 5.5 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 EEQ28591.1 - 0.061 13.5 9.3 0.13 12.5 9.3 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger BTB_2 PF02214.22 EEQ28592.1 - 1.1e-08 35.2 0.0 2.6e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 EEQ28592.1 - 0.02 15.1 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain Peptidase_S8 PF00082.22 EEQ28594.1 - 3.8e-33 115.0 15.9 9.7e-33 113.7 15.9 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ28594.1 - 1.3e-15 57.8 0.0 3.5e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I9 ketoacyl-synt PF00109.26 EEQ28595.1 - 5.4e-07 29.5 0.0 5.2e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Peptidase_M4_C PF02868.15 EEQ28595.1 - 0.031 14.1 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Vps26 PF03643.15 EEQ28595.1 - 0.039 13.0 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Pox_M2 PF04887.12 EEQ28595.1 - 0.097 12.2 0.0 5.2 6.5 0.0 2.0 1 1 1 2 2 2 0 Poxvirus M2 protein Pkinase PF00069.25 EEQ28596.1 - 5.4e-10 39.1 0.0 8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28596.1 - 0.00021 20.7 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glyoxalase_2 PF12681.7 EEQ28598.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Methyltransf_23 PF13489.6 EEQ28599.1 - 2.8e-06 27.2 0.0 3.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ28599.1 - 9.7e-06 26.2 0.3 5.2e-05 23.9 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ28599.1 - 0.038 14.6 0.0 0.058 14.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ28599.1 - 0.05 13.4 0.1 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 EEQ28599.1 - 0.055 13.2 0.0 1.4 8.6 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_25 PF13649.6 EEQ28599.1 - 0.089 13.5 0.1 0.47 11.2 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 EEQ28600.1 - 0.011 14.8 0.9 0.1 11.6 0.3 2.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain MFS_1 PF07690.16 EEQ28601.1 - 9.3e-20 70.8 45.9 9.3e-11 41.2 19.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily VCBS PF13517.6 EEQ28605.1 - 2.9e-25 88.6 30.9 1.8e-09 38.0 4.1 4.3 2 2 2 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EEQ28605.1 - 4.6e-18 66.2 0.2 9.3e-18 65.2 0.2 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EEQ28605.1 - 2.4e-10 40.8 0.0 5.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 EEQ28605.1 - 4.1e-08 32.8 3.5 1.6 8.1 0.0 5.2 2 1 3 5 5 5 4 Insecticide toxin TcdB middle/N-terminal region Dockerin_1 PF00404.18 EEQ28605.1 - 1.2e-07 31.8 1.5 5.9 7.2 0.0 5.5 5 0 0 5 5 5 2 Dockerin type I domain FG-GAP PF01839.23 EEQ28605.1 - 9.9e-07 28.8 19.0 0.38 10.9 0.0 6.5 7 0 0 7 7 7 5 FG-GAP repeat Lipase_GDSL_3 PF14606.6 EEQ28605.1 - 0.0002 21.6 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FliC PF12445.8 EEQ28605.1 - 0.14 12.5 0.3 5.4 7.4 0.0 2.7 2 0 0 2 2 2 0 Flagellin protein Aspzincin_M35 PF14521.6 EEQ28605.1 - 0.16 12.5 0.0 7.8 7.0 0.0 2.5 1 1 1 2 2 2 0 Lysine-specific metallo-endopeptidase SUR7 PF06687.12 EEQ28609.1 - 1.6e-33 116.1 9.7 1.9e-33 115.9 9.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family S_tail_recep_bd PF14928.6 EEQ28610.1 - 0.45 11.2 2.3 1.2 9.8 2.3 1.6 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain Acetyltransf_1 PF00583.25 EEQ28611.1 - 1.4e-11 44.7 0.0 1.9e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ28611.1 - 4.3e-08 33.2 0.0 5.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ28611.1 - 2.6e-07 30.5 0.0 4.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EEQ28611.1 - 2.4e-05 24.7 0.0 4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEQ28611.1 - 0.0033 17.5 0.1 0.005 16.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Golgin_A5 PF09787.9 EEQ28612.1 - 0.62 9.5 29.8 0.058 12.9 10.1 3.1 3 0 0 3 3 3 0 Golgin subfamily A member 5 Macoilin PF09726.9 EEQ28612.1 - 1.4 7.4 36.9 3.4 6.1 37.1 1.4 1 1 0 1 1 1 0 Macoilin family Pkinase PF00069.25 EEQ28613.1 - 0.076 12.4 0.0 0.4 10.0 0.0 2.1 1 1 1 2 2 2 0 Protein kinase domain LsmAD PF06741.13 EEQ28614.1 - 2.4e-28 98.5 4.8 7.1e-28 97.0 4.8 1.9 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 EEQ28614.1 - 2.5e-20 72.4 0.0 5e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Herpes_pp85 PF04637.12 EEQ28614.1 - 0.05 12.0 0.1 0.18 10.2 0.1 1.9 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) AIP3 PF03915.13 EEQ28615.1 - 1.5e-150 501.8 4.2 2.2e-150 501.3 4.2 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 MIP-T3_C PF17749.1 EEQ28615.1 - 0.00039 20.4 2.9 0.02 14.8 1.3 3.0 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region RasGAP_C PF03836.15 EEQ28615.1 - 0.016 15.4 1.9 0.49 10.5 0.4 3.5 4 0 0 4 4 4 0 RasGAP C-terminus Lectin_N PF03954.14 EEQ28615.1 - 0.081 12.7 0.2 0.32 10.7 0.2 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain COG2 PF06148.11 EEQ28615.1 - 0.23 11.5 4.6 3.6 7.7 0.0 3.6 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.6 EEQ28615.1 - 0.31 9.6 1.6 1.6 7.3 1.6 1.9 1 1 0 1 1 1 0 AAA domain HsbA PF12296.8 EEQ28615.1 - 0.39 11.1 2.9 2.1 8.8 0.1 3.3 4 0 0 4 4 4 0 Hydrophobic surface binding protein A DUF1664 PF07889.12 EEQ28615.1 - 0.74 9.9 3.3 4.7 7.3 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EEQ28615.1 - 1.2 9.7 4.6 0.84 10.1 0.1 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 EEQ28615.1 - 2.6 6.9 10.1 17 4.1 6.6 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein DivIC PF04977.15 EEQ28615.1 - 4.5 7.1 6.9 1.9 8.3 0.1 3.7 5 0 0 5 5 5 0 Septum formation initiator CAP_N PF01213.19 EEQ28616.1 - 7 6.0 5.1 10 5.5 5.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ACOX PF01756.19 EEQ28617.1 - 1e-46 158.8 0.0 1.8e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EEQ28617.1 - 3.2e-31 108.5 0.7 7e-31 107.4 0.7 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EEQ28617.1 - 1.6e-12 47.4 0.0 5.9e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EEQ28617.1 - 1.1e-06 29.0 0.1 0.0034 17.6 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain ESSS PF10183.9 EEQ28618.1 - 6e-15 55.3 0.0 6.2e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RNB PF00773.19 EEQ28619.1 - 6.5e-97 324.8 0.1 1.1e-96 324.0 0.1 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EEQ28619.1 - 5.9e-29 100.7 0.0 1.7e-28 99.2 0.0 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EEQ28619.1 - 2.6e-26 91.4 1.9 6.6e-26 90.1 1.9 1.7 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 EEQ28619.1 - 1.9e-21 75.9 0.0 5.6e-21 74.4 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EEQ28619.1 - 4.7e-10 39.5 0.1 2.3e-06 27.7 0.0 3.0 2 0 0 2 2 2 2 Cold shock domain PIN_4 PF13638.6 EEQ28619.1 - 2.7e-09 37.4 0.9 9.6e-09 35.6 0.3 2.2 2 0 0 2 2 2 1 PIN domain THDPS_N PF14790.6 EEQ28619.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Dis3l2_C_term PF17877.1 EEQ28619.1 - 0.14 12.5 1.0 0.54 10.6 1.0 2.1 1 1 0 1 1 1 0 DIS3-like exonuclease 2 C terminal MFS_1 PF07690.16 EEQ28620.1 - 1.6e-26 93.1 72.5 1.8e-21 76.5 42.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ28620.1 - 2.8e-09 36.0 25.5 1.2e-05 24.0 9.1 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein LIM PF00412.22 EEQ28621.1 - 3.7e-26 91.1 23.0 1.7e-10 40.9 2.8 3.9 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.6 EEQ28621.1 - 0.0068 16.9 0.1 0.0068 16.9 0.1 2.5 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain MRP-S31 PF15433.6 EEQ28621.1 - 0.57 9.8 4.1 0.8 9.3 4.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Methyltransf_4 PF02390.17 EEQ28622.1 - 2.8e-47 160.4 0.6 2.1e-45 154.3 0.6 2.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EEQ28622.1 - 0.00017 22.2 0.0 0.0021 18.8 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 EEQ28622.1 - 0.00064 19.3 0.0 0.019 14.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EEQ28622.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ28622.1 - 0.0017 19.0 0.0 0.46 11.2 0.0 3.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ28622.1 - 0.0033 18.1 0.0 0.011 16.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF4191 PF13829.6 EEQ28622.1 - 0.05 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Methyltransf_32 PF13679.6 EEQ28622.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ESCRT-II PF05871.12 EEQ28623.1 - 1.2e-52 177.9 1.7 1.5e-52 177.5 1.7 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit RTT107_BRCT_5 PF16770.5 EEQ28624.1 - 2.6e-31 107.4 0.0 3.7e-29 100.6 0.0 3.1 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EEQ28624.1 - 2.2e-30 104.9 0.3 1.3e-08 35.1 0.0 6.7 6 1 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EEQ28624.1 - 4.3e-29 100.2 5.8 2.9e-18 65.6 0.2 5.6 6 1 0 6 6 6 3 twin BRCT domain BRCT_2 PF16589.5 EEQ28624.1 - 9.3e-24 83.7 0.3 0.0028 18.0 0.0 6.5 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EEQ28624.1 - 0.0015 18.8 0.4 16 5.8 0.0 4.7 5 0 0 5 5 5 1 DNA ligase 3 BRCT domain Ofd1_CTDD PF10637.9 EEQ28624.1 - 0.061 12.7 0.3 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Ceramidase PF05875.12 EEQ28626.1 - 1.7e-91 306.3 5.2 2.8e-91 305.6 5.2 1.3 1 1 0 1 1 1 1 Ceramidase Prefoldin_2 PF01920.20 EEQ28628.1 - 4.9e-07 29.7 0.3 7.6e-07 29.1 0.3 1.3 1 0 0 1 1 1 1 Prefoldin subunit GatB_Yqey PF02637.18 EEQ28628.1 - 0.039 13.9 0.3 0.047 13.6 0.3 1.1 1 0 0 1 1 1 0 GatB domain Mito_carr PF00153.27 EEQ28630.1 - 1.3e-52 175.7 2.8 8.2e-19 67.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ28630.1 - 0.91 8.6 4.0 4 6.5 0.0 3.2 3 1 0 3 3 3 0 Gammaproteobacterial serine protease Granulin PF00396.18 EEQ28631.1 - 1.9 8.9 15.4 10 6.5 11.9 3.0 2 1 1 3 3 3 0 Granulin Pkinase PF00069.25 EEQ28633.1 - 4e-31 108.3 0.0 8.1e-31 107.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28633.1 - 9.3e-15 54.6 0.0 5.9e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ28633.1 - 1.2e-05 24.3 0.0 2.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEQ28633.1 - 0.017 15.1 0.6 0.072 13.0 0.2 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4834 PF16118.5 EEQ28634.1 - 0.0079 17.1 0.2 1 10.4 0.0 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4834) DUF4690 PF15756.5 EEQ28634.1 - 0.025 15.2 2.0 0.025 15.2 2.0 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 EEQ28634.1 - 0.16 12.9 0.0 22 6.0 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 EEQ28634.1 - 0.25 11.2 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 Rcd1 PF04078.13 EEQ28635.1 - 8e-126 418.6 3.5 1e-125 418.3 3.5 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Macoilin PF09726.9 EEQ28635.1 - 0.012 14.2 10.3 0.014 14.0 10.3 1.1 1 0 0 1 1 1 0 Macoilin family PAT1 PF09770.9 EEQ28635.1 - 0.36 9.0 26.2 0.43 8.8 26.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 EEQ28635.1 - 0.48 9.1 8.6 0.64 8.6 8.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAF1_ABF1 PF04684.13 EEQ28635.1 - 0.72 8.8 16.9 0.94 8.5 16.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 EEQ28635.1 - 1 9.3 35.2 1.5 8.7 35.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NST1 PF13945.6 EEQ28635.1 - 1.3 9.1 18.7 2 8.5 18.7 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Otopetrin PF03189.13 EEQ28635.1 - 1.4 7.6 8.5 0.061 12.1 2.1 1.7 2 0 0 2 2 2 0 Otopetrin MMR1 PF08505.10 EEQ28635.1 - 4.4 7.5 17.8 6.9 6.9 17.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SRP-alpha_N PF04086.13 EEQ28635.1 - 4.6 7.1 15.2 6.7 6.5 15.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 EEQ28635.1 - 6.2 5.5 19.6 9.1 4.9 19.6 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 EEQ28635.1 - 7.6 5.8 14.3 13 5.1 14.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.7 EEQ28635.1 - 7.6 4.5 15.0 13 3.7 15.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.11 EEQ28635.1 - 9.7 4.5 13.6 15 3.9 13.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 PHD PF00628.29 EEQ28636.1 - 7e-09 35.5 9.4 1.6e-08 34.3 9.4 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEQ28636.1 - 0.0017 17.8 5.0 0.0017 17.8 5.0 2.1 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 EEQ28636.1 - 0.27 11.6 6.4 0.17 12.2 1.6 2.4 2 0 0 2 2 2 0 C1 domain HypA PF01155.19 EEQ28636.1 - 1.7 8.7 4.2 5.9 7.0 0.9 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF913 PF06025.12 EEQ28636.1 - 5 6.0 9.3 12 4.7 9.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spt20 PF12090.8 EEQ28636.1 - 8.4 5.9 23.6 0.58 9.7 6.8 3.0 3 0 0 3 3 3 0 Spt20 family HMG_box PF00505.19 EEQ28640.1 - 3.8e-10 40.0 0.9 8.9e-10 38.8 0.9 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box Sld5 PF05916.11 EEQ28641.1 - 2e-11 44.3 0.9 6.1e-11 42.7 0.9 1.8 1 1 0 1 1 1 1 GINS complex protein INT_SG_DDX_CT_C PF15300.6 EEQ28641.1 - 0.071 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Sulfate_transp PF00916.20 EEQ28642.1 - 3.1e-58 197.4 23.1 5.1e-58 196.6 23.1 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EEQ28642.1 - 1.2e-13 50.9 0.0 2.4e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EEQ28642.1 - 3.5e-13 49.2 0.1 6.6e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain DUF3180 PF11377.8 EEQ28642.1 - 3.3 7.8 14.7 12 6.0 5.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) PH_6 PF15406.6 EEQ28643.1 - 2.4e-33 114.8 1.4 2.4e-33 114.8 1.4 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EEQ28643.1 - 6e-10 39.6 0.0 1.9e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 PH domain PNTB PF02233.16 EEQ28645.1 - 1.2e-175 584.9 25.3 1.2e-175 584.9 25.3 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EEQ28645.1 - 1.4e-66 223.9 0.1 5.2e-66 222.0 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EEQ28645.1 - 7.4e-43 146.1 0.0 1.9e-42 144.8 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EEQ28645.1 - 8.9e-24 83.8 5.1 8.9e-24 83.8 5.1 6.0 3 2 3 6 6 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EEQ28645.1 - 0.0052 16.2 0.1 0.62 9.4 0.0 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EEQ28645.1 - 0.027 13.7 0.1 0.084 12.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 EEQ28645.1 - 0.042 13.6 0.6 0.26 11.0 0.3 2.5 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ATP-synt_DE_N PF02823.16 EEQ28645.1 - 0.074 13.0 0.0 6.9 6.7 0.0 2.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ADH_zinc_N PF00107.26 EEQ28645.1 - 0.08 12.9 0.6 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase GIDA PF01134.22 EEQ28645.1 - 0.1 11.7 0.8 0.18 10.9 0.8 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EEQ28645.1 - 0.11 12.7 1.5 0.69 10.2 1.5 2.6 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DEC-1_N PF04625.13 EEQ28645.1 - 0.63 9.0 2.7 1.2 8.1 2.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region bZIP_2 PF07716.15 EEQ28646.1 - 5.6e-09 35.9 6.9 1e-08 35.1 6.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EEQ28646.1 - 1.3e-06 28.4 6.4 2.2e-06 27.6 6.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF4094 PF13334.6 EEQ28646.1 - 0.022 15.2 0.8 0.038 14.4 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) bZIP_Maf PF03131.17 EEQ28646.1 - 0.089 13.3 5.9 0.18 12.4 5.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Asn_synthase PF00733.21 EEQ28647.1 - 2.7e-14 53.6 0.5 0.00017 21.4 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EEQ28647.1 - 5.1e-05 23.2 0.0 0.00053 19.9 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain VPS9 PF02204.18 EEQ28648.1 - 2.6e-28 98.3 0.0 4.8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EEQ28648.1 - 1.3e-16 60.6 0.1 3e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) VIT1 PF01988.19 EEQ28650.1 - 1.8e-61 207.8 2.5 2.1e-61 207.5 2.5 1.0 1 0 0 1 1 1 1 VIT family DUF4282 PF14110.6 EEQ28650.1 - 6.6 7.5 8.9 7.7 7.3 5.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) DUF4202 PF13875.6 EEQ28651.1 - 1.1e-80 269.9 2.1 1.2e-80 269.8 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) AAA PF00004.29 EEQ28651.1 - 0.0046 17.4 0.1 0.22 11.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) 2-ph_phosp PF04029.14 EEQ28651.1 - 0.23 10.6 1.8 3.2 6.8 0.2 2.4 2 1 0 2 2 2 0 2-phosphosulpholactate phosphatase Thr_synth_N PF14821.6 EEQ28652.1 - 4.1e-28 97.4 0.0 1e-27 96.2 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EEQ28652.1 - 1.7e-16 60.5 0.0 1.1e-15 57.8 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Hydrolase PF00702.26 EEQ28653.1 - 5e-06 27.0 0.0 7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ28653.1 - 0.00021 21.4 0.0 0.0011 19.0 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SMC_ScpB PF04079.16 EEQ28653.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Rox3 PF08633.10 EEQ28654.1 - 6.4e-67 225.8 0.9 2.1e-66 224.1 0.1 2.0 2 0 0 2 2 2 1 Rox3 mediator complex subunit MAGI_u5 PF16666.5 EEQ28654.1 - 0.1 12.8 0.3 0.1 12.8 0.3 3.3 3 1 0 3 3 3 0 Unstructured region on MAGI Fungal_trans PF04082.18 EEQ28655.1 - 2.4e-13 49.7 0.4 3.1e-12 46.1 0.1 2.2 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ28655.1 - 8.8e-08 32.2 13.4 1.8e-07 31.2 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.15 EEQ28655.1 - 0.1 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Peptidase_M14 PF00246.24 EEQ28656.1 - 1.1e-82 278.1 0.2 2.9e-82 276.7 0.0 1.6 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EEQ28656.1 - 3.3e-11 43.4 0.0 9.2e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide AstE_AspA PF04952.14 EEQ28656.1 - 0.084 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_S8 PF00082.22 EEQ28657.1 - 1.4e-29 103.3 16.6 3.9e-29 101.8 16.7 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ28657.1 - 3.9e-15 56.3 0.0 8.1e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 p450 PF00067.22 EEQ28660.1 - 2.8e-62 211.0 0.0 4.2e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arylsulfotran_2 PF14269.6 EEQ28661.1 - 2.3e-109 365.4 1.0 3.2e-109 364.9 1.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) FA_hydroxylase PF04116.13 EEQ28662.1 - 9.7e-20 71.3 15.6 4e-19 69.3 12.5 2.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily p450 PF00067.22 EEQ28663.1 - 1.2e-15 57.3 0.0 1.6e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EEQ28664.1 - 4.6e-13 48.8 0.1 7e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ28664.1 - 5.1e-08 32.9 9.2 1.1e-07 31.8 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex16 PF08610.10 EEQ28664.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Glycogen_syn PF05693.13 EEQ28664.1 - 0.27 9.8 0.1 0.37 9.3 0.1 1.1 1 0 0 1 1 1 0 Glycogen synthase IU_nuc_hydro PF01156.19 EEQ28666.1 - 6e-33 114.7 0.0 1e-32 114.0 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.20 EEQ28666.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain HLH PF00010.26 EEQ28667.1 - 4.4e-14 52.2 0.7 8.2e-14 51.3 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glycos_transf_1 PF00534.20 EEQ28669.1 - 8.5e-14 51.5 0.0 1.4e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEQ28669.1 - 2.1e-07 31.4 0.0 4.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EEQ28669.1 - 0.063 13.7 0.0 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Amidase PF01425.21 EEQ28671.1 - 5.5e-94 315.7 0.0 8.1e-94 315.1 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF4748 PF15932.5 EEQ28673.1 - 0.4 10.5 0.0 0.4 10.5 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4748) SURF4 PF02077.15 EEQ28674.1 - 7e-95 317.6 6.1 7.9e-95 317.5 6.1 1.0 1 0 0 1 1 1 1 SURF4 family DUF1405 PF07187.11 EEQ28674.1 - 0.0096 15.9 3.0 0.0096 15.9 3.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1405) UPF0139 PF03669.13 EEQ28674.1 - 0.012 15.5 1.2 0.043 13.7 0.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0139) DoxX PF07681.12 EEQ28674.1 - 0.025 15.2 20.6 0.11 13.2 5.1 3.1 3 2 0 3 3 3 0 DoxX Optomotor-blind PF11078.8 EEQ28675.1 - 0.072 13.7 0.2 0.17 12.5 0.2 1.6 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region LSM PF01423.22 EEQ28677.1 - 6.8e-17 60.9 0.1 9.3e-17 60.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain WH2 PF02205.20 EEQ28678.1 - 8.8e-10 38.1 0.3 8.8e-10 38.1 0.3 1.8 2 0 0 2 2 2 1 WH2 motif Ribosomal_L1 PF00687.21 EEQ28680.1 - 1.2e-46 159.1 0.1 1.3e-46 158.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Acetyltransf_1 PF00583.25 EEQ28681.1 - 2e-09 37.7 0.0 3.3e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ28681.1 - 1.5e-07 31.7 0.0 2.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ28681.1 - 5.9e-07 29.5 0.0 3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ28681.1 - 7.2e-07 29.1 0.0 5.5e-06 26.3 0.0 2.2 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 EEQ28681.1 - 0.012 16.3 0.2 0.082 13.6 0.2 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EEQ28681.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Arf PF00025.21 EEQ28682.1 - 3.1e-79 264.5 0.2 3.5e-79 264.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EEQ28682.1 - 2.2e-15 56.5 0.0 2.7e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EEQ28682.1 - 1.9e-14 53.9 0.1 2.7e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EEQ28682.1 - 3e-13 49.7 0.0 3.3e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EEQ28682.1 - 3.1e-13 49.6 1.5 2e-09 37.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EEQ28682.1 - 1.2e-10 41.1 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ28682.1 - 3.3e-06 27.2 0.0 4.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EEQ28682.1 - 0.0085 15.4 0.6 0.023 14.0 0.6 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 EEQ28682.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 APH PF01636.23 EEQ28685.1 - 4.3e-15 56.3 0.0 7e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ28685.1 - 0.00086 18.3 0.0 0.046 12.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) DUF92 PF01940.16 EEQ28687.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 SARAF PF06682.12 EEQ28687.1 - 0.13 11.9 1.1 0.18 11.4 1.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CD34_antigen PF06365.12 EEQ28687.1 - 0.16 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF3405 PF11885.8 EEQ28688.1 - 3.2e-233 775.0 0.8 3.8e-233 774.8 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) CHRD PF07452.12 EEQ28690.1 - 0.045 14.7 0.0 0.045 14.7 0.0 2.0 2 0 0 2 2 2 0 CHRD domain Collagen PF01391.18 EEQ28691.1 - 0.0016 18.2 3.4 0.0016 18.2 3.4 1.7 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) SDA1 PF05285.12 EEQ28691.1 - 0.47 9.8 16.4 0.71 9.2 16.4 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EEQ28691.1 - 0.54 8.5 12.1 0.69 8.1 12.1 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EEQ28691.1 - 3 7.1 13.6 4.1 6.7 13.6 1.4 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EEQ28691.1 - 8 4.5 18.0 10 4.2 18.0 1.1 1 0 0 1 1 1 0 Nop14-like family Choline_kinase PF01633.20 EEQ28692.1 - 2.3e-47 161.4 0.0 2.9e-46 157.7 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EEQ28692.1 - 2.7e-09 37.3 0.3 1e-08 35.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EEQ28692.1 - 0.029 13.7 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase CHORD PF04968.12 EEQ28693.1 - 7.7e-51 170.7 18.4 1.9e-26 92.5 5.5 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 EEQ28693.1 - 3.7e-12 47.1 0.1 5.5e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.19 EEQ28693.1 - 0.13 12.1 8.8 2.2 8.2 0.4 3.3 3 0 0 3 3 3 0 BTK motif DUF836 PF05768.14 EEQ28694.1 - 2e-13 50.6 0.0 2.3e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EEQ28694.1 - 0.01 16.0 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin HpcH_HpaI PF03328.14 EEQ28695.1 - 1.6e-30 105.9 0.0 2.2e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family HNH_2 PF13391.6 EEQ28696.1 - 2.2e-14 53.4 0.0 4.3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Fungal_trans PF04082.18 EEQ28697.1 - 3.5e-15 55.8 0.0 5.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ28697.1 - 1.4e-12 47.6 27.7 8.9e-07 28.9 7.7 2.4 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 EEQ28698.1 - 2.4e-30 105.7 0.3 3.4e-30 105.2 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EEQ28698.1 - 5.5e-23 81.0 0.2 1.1e-22 80.0 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EEQ28698.1 - 8.7e-13 48.9 0.2 4.1e-12 46.7 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EEQ28698.1 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 14-3-3 PF00244.20 EEQ28699.1 - 3.5e-08 33.2 0.1 5.6e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein tRNA-synt_1b PF00579.25 EEQ28700.1 - 3.9e-17 62.5 0.0 3.2e-16 59.5 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2714 PF10896.8 EEQ28702.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) Peptidase_S64 PF08192.11 EEQ28703.1 - 0.07 11.6 0.1 0.15 10.5 0.1 1.4 1 1 0 1 1 1 0 Peptidase family S64 DUF3237 PF11578.8 EEQ28704.1 - 1.5e-34 119.0 0.1 5e-33 114.0 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) Phenol_MetA_deg PF13557.6 EEQ28704.1 - 0.029 14.3 0.3 0.036 14.0 0.3 1.1 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation GRP PF07172.11 EEQ28705.1 - 0.0005 20.7 7.8 0.00073 20.2 7.8 1.3 1 0 0 1 1 1 1 Glycine rich protein family MAP17 PF15807.5 EEQ28705.1 - 0.0014 18.9 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SARAF PF06682.12 EEQ28705.1 - 0.032 13.9 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3262 PF11660.8 EEQ28705.1 - 0.036 14.4 0.1 0.057 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) PAP_PilO PF06864.12 EEQ28705.1 - 0.064 12.1 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) SpoIIIAH PF12685.7 EEQ28705.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein FeoB_associated PF12669.7 EEQ28705.1 - 0.14 12.6 0.7 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein UPF0542 PF15086.6 EEQ28705.1 - 0.17 11.9 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 TNFR_16_TM PF18422.1 EEQ28705.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain EMP24_GP25L PF01105.24 EEQ28706.1 - 3e-48 164.2 0.0 3.6e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1408 PF07193.11 EEQ28706.1 - 0.097 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) Myb_DNA-bind_6 PF13921.6 EEQ28707.1 - 0.0031 17.7 4.6 0.022 15.0 0.6 3.0 3 1 1 4 4 4 1 Myb-like DNA-binding domain HEPPP_synt_1 PF07307.11 EEQ28707.1 - 0.055 13.1 0.2 0.055 13.1 0.2 1.7 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 PRKG1_interact PF15898.5 EEQ28707.1 - 0.1 13.5 0.4 0.1 13.5 0.4 2.9 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF3106 PF11304.8 EEQ28707.1 - 4.3 7.8 16.8 2.5 8.6 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Sec2p PF06428.11 EEQ28707.1 - 4.4 7.3 9.2 0.13 12.2 1.2 2.4 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Phage_lysozyme2 PF18013.1 EEQ28707.1 - 8.6 6.4 7.0 2.2 8.3 3.6 1.8 2 1 0 2 2 2 0 Phage tail lysozyme Glyco_hydro_17 PF00332.18 EEQ28708.1 - 9.3e-32 110.9 0.1 9.8e-31 107.5 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PAM2 PF07145.15 EEQ28709.1 - 0.00056 19.4 9.8 0.42 10.4 0.0 4.4 3 0 0 3 3 3 3 Ataxin-2 C-terminal region DUF2508 PF10704.9 EEQ28709.1 - 0.01 16.0 0.5 0.01 16.0 0.5 4.4 7 0 0 7 7 7 0 Protein of unknown function (DUF2508) DUF3425 PF11905.8 EEQ28710.1 - 7.7e-12 45.3 0.2 1.5e-11 44.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EEQ28710.1 - 0.003 17.6 18.4 0.041 14.0 18.4 2.1 1 1 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.11 EEQ28710.1 - 0.03 14.2 3.3 0.061 13.2 3.3 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region PRKG1_interact PF15898.5 EEQ28710.1 - 0.082 13.8 12.3 0.13 13.2 12.3 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF2937 PF11157.8 EEQ28710.1 - 0.12 12.1 1.3 0.19 11.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) GBP_C PF02841.14 EEQ28710.1 - 2.8 7.3 11.5 3.9 6.8 11.5 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF5094 PF17015.5 EEQ28710.1 - 7.5 6.6 8.9 11 6.1 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) GLE1 PF07817.13 EEQ28711.1 - 2e-40 138.6 0.0 5.4e-40 137.2 0.0 1.6 1 1 0 1 1 1 1 GLE1-like protein MitMem_reg PF13012.6 EEQ28711.1 - 0.67 10.4 5.3 16 5.9 0.3 3.0 3 2 0 3 3 3 0 Maintenance of mitochondrial structure and function AF-4 PF05110.13 EEQ28711.1 - 0.93 7.5 34.8 1.2 7.2 34.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RNB PF00773.19 EEQ28712.1 - 7.6e-83 278.5 0.7 1.2e-82 277.8 0.0 1.7 2 0 0 2 2 2 1 RNB domain Dis3l2_C_term PF17877.1 EEQ28712.1 - 1.4e-25 89.4 0.1 9.1e-25 86.8 0.0 2.5 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 EEQ28712.1 - 7.2e-25 86.8 0.0 1.7e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EEQ28712.1 - 7.7e-05 22.8 0.0 0.052 13.7 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EEQ28712.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain TFIIA PF03153.13 EEQ28712.1 - 0.0018 18.3 22.4 0.0018 18.3 22.4 3.5 3 1 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit UQ_con PF00179.26 EEQ28713.1 - 1.6e-36 125.0 0.2 4.4e-36 123.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ28713.1 - 0.0012 18.6 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic E2 family B Herpes_capsid PF06112.11 EEQ28714.1 - 9.2 6.3 18.8 11 6.1 18.8 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MMgT PF10270.9 EEQ28715.1 - 1.5e-32 111.9 0.0 1.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.19 EEQ28716.1 - 2.7e-32 110.8 1.6 4e-32 110.2 1.6 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EEQ28716.1 - 1.4e-07 31.8 0.1 1.4e-07 31.8 0.1 2.7 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region AAA_2 PF07724.14 EEQ28717.1 - 5.2e-46 156.9 0.0 3.4e-44 151.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EEQ28717.1 - 5.3e-35 119.5 1.7 5.3e-35 119.5 1.7 2.5 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EEQ28717.1 - 1.9e-26 91.9 0.1 1.9e-26 91.9 0.1 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EEQ28717.1 - 5e-18 65.8 0.0 3.8e-09 37.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEQ28717.1 - 1.6e-12 47.6 0.0 2.1e-07 31.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EEQ28717.1 - 3.5e-08 33.3 0.2 0.00026 20.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 EEQ28717.1 - 7.9e-08 32.9 9.6 0.00031 21.1 0.4 4.2 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EEQ28717.1 - 2.9e-06 27.6 2.8 0.044 14.1 0.0 3.7 3 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EEQ28717.1 - 1.3e-05 25.0 0.0 0.047 13.4 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein TniB PF05621.11 EEQ28717.1 - 1.6e-05 24.4 0.1 0.02 14.3 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_14 PF13173.6 EEQ28717.1 - 2.5e-05 24.3 0.2 0.072 13.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 EEQ28717.1 - 3.1e-05 24.0 0.3 0.11 12.4 0.0 2.7 3 0 0 3 3 2 2 NACHT domain AAA_7 PF12775.7 EEQ28717.1 - 4.3e-05 23.1 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 EEQ28717.1 - 0.00034 20.9 1.6 0.04 14.2 0.0 3.4 3 1 1 4 4 3 1 AAA domain AAA_18 PF13238.6 EEQ28717.1 - 0.00048 20.7 0.1 2 8.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EEQ28717.1 - 0.00094 19.0 0.0 0.66 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EEQ28717.1 - 0.0013 18.4 0.1 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 EEQ28717.1 - 0.0022 17.9 7.4 4.5 7.1 0.0 4.3 3 2 1 4 4 4 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EEQ28717.1 - 0.0025 17.2 0.1 2 7.8 0.1 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EEQ28717.1 - 0.0031 18.0 1.2 0.41 11.2 0.0 3.0 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.22 EEQ28717.1 - 0.0046 17.3 0.1 1.9 8.9 0.0 2.9 2 1 0 2 2 2 1 RNA helicase Roc PF08477.13 EEQ28717.1 - 0.0072 16.5 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 EEQ28717.1 - 0.0091 16.0 0.0 9 6.3 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEQ28717.1 - 0.0097 16.3 0.9 0.24 11.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EEQ28717.1 - 0.011 15.5 0.0 0.54 10.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EEQ28717.1 - 0.013 15.5 1.1 7.3 6.6 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EEQ28717.1 - 0.013 15.4 1.0 3 7.7 0.0 2.8 3 0 0 3 3 2 0 RsgA GTPase Zeta_toxin PF06414.12 EEQ28717.1 - 0.016 14.5 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 EEQ28717.1 - 0.023 13.6 0.1 0.71 8.7 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 EEQ28717.1 - 0.024 14.2 0.1 0.56 9.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EEQ28717.1 - 0.026 14.7 0.1 8.9 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EEQ28717.1 - 0.038 13.2 0.4 0.67 9.1 0.2 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF815) FapA PF03961.13 EEQ28717.1 - 0.049 12.2 3.9 0.083 11.5 3.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2564 PF10819.8 EEQ28717.1 - 0.06 13.7 0.2 0.17 12.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) DUF4094 PF13334.6 EEQ28717.1 - 0.08 13.4 0.2 0.58 10.6 0.3 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4094) AAA_30 PF13604.6 EEQ28717.1 - 0.087 12.5 6.4 0.18 11.5 0.4 3.7 4 1 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.17 EEQ28717.1 - 0.13 12.1 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 EEQ28717.1 - 0.14 12.0 1.3 0.75 9.5 0.0 2.8 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ28717.1 - 0.17 11.6 0.4 8.4 6.2 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain UvrD-helicase PF00580.21 EEQ28717.1 - 0.17 11.3 3.8 0.72 9.3 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain HisKA_2 PF07568.12 EEQ28717.1 - 0.3 11.2 1.5 0.98 9.6 0.9 2.1 2 0 0 2 2 1 0 Histidine kinase V_ATPase_I PF01496.19 EEQ28717.1 - 0.57 8.0 3.4 0.79 7.6 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 EEQ28717.1 - 3.8 8.0 19.9 2.5e+02 2.0 0.0 3.4 2 1 0 2 2 2 0 AAA domain DUF1664 PF07889.12 EEQ28717.1 - 8.1 6.5 5.8 22 5.1 5.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MutS_III PF05192.18 EEQ28718.1 - 4.9e-18 66.0 0.0 1.1e-17 64.9 0.0 1.5 2 0 0 2 2 2 1 MutS domain III MutS_V PF00488.21 EEQ28718.1 - 1.9e-15 57.4 0.0 4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.18 EEQ28718.1 - 0.0033 17.7 0.0 0.0097 16.2 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV Chorion_2 PF03964.15 EEQ28718.1 - 0.31 11.9 4.0 0.81 10.6 4.0 1.6 1 0 0 1 1 1 0 Chorion family 2 Sas10 PF09368.10 EEQ28719.1 - 2.8e-29 101.4 7.7 2.8e-29 101.4 7.7 3.2 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EEQ28719.1 - 4.8e-12 46.3 0.0 2.8e-11 43.9 0.0 2.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family HTH_WhiA PF02650.14 EEQ28719.1 - 0.25 11.7 2.4 0.63 10.4 1.3 2.3 2 0 0 2 2 2 0 WhiA C-terminal HTH domain adh_short PF00106.25 EEQ28720.1 - 3.4e-24 85.4 0.0 5.3e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ28720.1 - 5.3e-11 42.5 0.0 9.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ28720.1 - 1.3e-10 41.5 0.0 9.2e-10 38.7 0.0 2.0 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EEQ28720.1 - 0.0024 17.3 0.0 0.0047 16.4 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 EEQ28720.1 - 0.0068 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Epimerase PF01370.21 EEQ28720.1 - 0.0089 15.5 0.0 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EEQ28720.1 - 0.013 14.8 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 EEQ28720.1 - 0.014 15.6 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EEQ28720.1 - 0.016 15.3 0.1 0.071 13.2 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EEQ28720.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EEQ28720.1 - 0.11 13.1 0.1 0.3 11.7 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FA_hydroxylase PF04116.13 EEQ28721.1 - 4.5e-18 65.9 9.2 4.5e-18 65.9 9.2 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.19 EEQ28722.1 - 1.4e-37 128.6 0.1 2.4e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.13 EEQ28723.1 - 3e-26 91.8 0.0 4.5e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EEQ28723.1 - 4.9e-14 52.4 0.7 1.7e-13 50.7 0.8 1.8 2 0 0 2 2 2 1 UCH-binding domain Ion_trans PF00520.31 EEQ28724.1 - 3.3e-125 416.2 82.9 8e-40 136.6 6.1 4.6 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 EEQ28724.1 - 0.0031 17.3 0.0 0.0077 16.0 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 EEQ28724.1 - 0.036 13.6 0.0 0.099 12.2 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EEQ28724.1 - 0.14 12.1 0.0 0.56 10.3 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Aft1_OSA PF11785.8 EEQ28724.1 - 0.54 10.7 4.0 1.5 9.3 4.0 1.8 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain SET PF00856.28 EEQ28726.1 - 8.3e-18 65.3 0.1 1.9e-17 64.2 0.1 1.6 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 EEQ28726.1 - 2.3e-11 44.3 7.5 1.1e-10 42.2 3.2 2.3 2 0 0 2 2 2 2 Pre-SET motif Nop52 PF05997.12 EEQ28728.1 - 2.4e-56 191.0 0.1 4e-43 147.7 0.4 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TAN PF11640.8 EEQ28728.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair NOT2_3_5 PF04153.18 EEQ28728.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family Secretin_N_2 PF07655.13 EEQ28728.1 - 0.1 13.2 1.9 0.23 12.0 1.9 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain UBD PF16455.5 EEQ28729.1 - 9.6e-41 138.3 0.0 1.4e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 EEQ28729.1 - 0.0019 17.9 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EEQ28729.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EEQ28729.1 - 0.11 13.0 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PaREP1 PF05942.11 EEQ28729.1 - 0.17 11.8 0.1 2.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family baeRF_family2 PF18844.1 EEQ28729.1 - 0.57 10.2 3.6 0.16 12.0 0.3 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 DUF1604 PF07713.13 EEQ28730.1 - 2e-43 146.1 2.7 9.9e-42 140.7 2.3 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EEQ28730.1 - 1.2e-07 31.5 1.1 4.9e-07 29.5 0.6 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EEQ28730.1 - 0.013 15.6 6.3 0.048 13.7 0.1 3.5 3 0 0 3 3 3 0 G-patch domain BHD_2 PF10404.9 EEQ28730.1 - 1.1 10.3 4.9 99 4.0 3.0 3.8 2 1 0 2 2 2 0 Rad4 beta-hairpin domain 2 Pkinase PF00069.25 EEQ28731.1 - 2.4e-71 240.2 0.0 4.3e-71 239.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28731.1 - 1e-40 139.6 0.0 2.8e-40 138.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EEQ28731.1 - 8.5e-17 60.7 0.4 1.6e-16 59.8 0.4 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 EEQ28731.1 - 4.8e-07 29.1 0.0 8.9e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEQ28731.1 - 4e-06 26.3 0.0 7.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ28731.1 - 8e-06 25.4 0.0 9.6e-05 21.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EEQ28731.1 - 0.0025 17.8 0.1 0.23 11.3 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 EEQ28731.1 - 0.012 15.2 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 EEQ28731.1 - 0.023 14.3 0.5 0.065 12.8 0.5 1.7 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EEQ28731.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DAGK_cat PF00781.24 EEQ28732.1 - 2.5e-26 91.8 0.1 3.8e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain LrgB PF04172.16 EEQ28734.1 - 0.026 14.1 9.1 0.077 12.5 9.1 1.9 1 1 0 1 1 1 0 LrgB-like family Adaptin_N PF01602.20 EEQ28735.1 - 2.2e-94 316.9 11.7 3.9e-94 316.1 11.7 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EEQ28735.1 - 7.4e-58 194.4 0.3 1.7e-57 193.3 0.3 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EEQ28735.1 - 9.5e-56 187.3 0.0 3.9e-55 185.3 0.0 2.1 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EEQ28735.1 - 1.8e-12 47.6 11.3 1.6e-09 38.0 0.0 3.4 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ28735.1 - 9e-08 32.4 13.8 9.5e-06 25.9 0.0 5.1 5 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 EEQ28735.1 - 0.0004 20.8 2.1 0.021 15.3 0.0 4.4 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 EEQ28735.1 - 0.0012 18.9 1.1 4.3 7.9 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat AP4E_app_platf PF14807.6 EEQ28735.1 - 0.0069 16.7 0.1 0.024 15.0 0.1 2.0 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Arm PF00514.23 EEQ28735.1 - 0.039 14.0 2.1 14 5.9 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF4239 PF14023.6 EEQ28735.1 - 2.4 7.9 7.6 0.89 9.2 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Mago_nashi PF02792.14 EEQ28736.1 - 1.1e-50 171.4 7.0 3.4e-44 150.4 0.1 2.0 1 1 1 2 2 2 2 Mago nashi protein Vac_ImportDeg PF09783.9 EEQ28737.1 - 7.4e-62 207.9 1.5 9.5e-62 207.6 1.5 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Methyltransf_25 PF13649.6 EEQ28738.1 - 1.8e-06 28.6 0.0 4.1e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ28738.1 - 2.9e-06 27.9 0.0 5.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ28738.1 - 0.0014 18.4 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Pro-kuma_activ PF09286.11 EEQ28740.1 - 1.8e-38 132.0 0.9 4e-38 130.9 0.4 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EEQ28740.1 - 5.7e-05 22.5 1.6 0.00014 21.3 1.6 1.6 1 0 0 1 1 1 1 Subtilase family Myelin_PLP PF01275.19 EEQ28741.1 - 0.087 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Ank_2 PF12796.7 EEQ28742.1 - 1.4e-55 185.8 0.0 1.4e-14 54.4 0.0 7.0 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ28742.1 - 4.2e-42 142.0 0.1 2e-06 28.2 0.0 8.9 6 2 2 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ28742.1 - 3.6e-38 129.1 4.1 9.8e-08 32.1 0.0 9.7 4 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ28742.1 - 3.6e-37 122.1 0.0 0.016 15.7 0.0 12.8 14 0 0 14 14 14 8 Ankyrin repeat Ank PF00023.30 EEQ28742.1 - 1.4e-27 94.9 0.1 0.027 14.9 0.0 10.0 9 0 0 9 9 9 6 Ankyrin repeat SLS PF14611.6 EEQ28742.1 - 0.077 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Aa_trans PF01490.18 EEQ28743.1 - 8.5e-27 93.9 33.9 1.5e-26 93.1 33.9 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein GCV_T PF01571.21 EEQ28744.1 - 8.5e-77 258.0 0.0 2.1e-76 256.7 0.0 1.6 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EEQ28744.1 - 4.1e-18 65.1 0.2 8.2e-18 64.1 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain APS_kinase PF01583.20 EEQ28745.1 - 4.4e-59 198.9 0.3 6.9e-58 195.0 0.1 2.5 2 1 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 EEQ28745.1 - 0.00016 21.8 1.3 0.0019 18.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ28745.1 - 0.0006 20.4 0.0 0.0036 17.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EEQ28745.1 - 0.014 15.9 0.1 0.14 12.7 0.0 2.2 2 1 0 2 2 2 0 ABC transporter PhoH PF02562.16 EEQ28745.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 EEQ28745.1 - 0.028 14.1 1.5 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EEQ28745.1 - 0.038 14.4 0.1 0.038 14.4 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain CbiA PF01656.23 EEQ28745.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain V-ATPase_C PF03223.15 EEQ28746.1 - 6.6e-124 414.1 0.0 7.7e-124 413.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 EEQ28746.1 - 0.051 14.2 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Cep57_MT_bd PF06657.13 EEQ28746.1 - 0.14 12.6 0.2 24 5.5 0.0 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 4HBT PF03061.22 EEQ28747.1 - 1.5e-11 44.5 0.0 2.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Ligase_CoA PF00549.19 EEQ28748.1 - 2.6e-34 118.2 2.1 5.6e-17 62.0 0.1 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 EEQ28748.1 - 3.2e-17 63.0 1.5 5e-17 62.4 0.1 2.0 3 0 0 3 3 3 1 CoA binding domain Succ_CoA_lig PF13607.6 EEQ28748.1 - 1.6e-09 37.6 0.1 9.4e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EEQ28748.1 - 0.017 15.6 0.1 0.044 14.3 0.1 1.7 1 0 0 1 1 1 0 CoA binding domain UBA_5 PF16577.5 EEQ28748.1 - 0.048 13.8 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 UBA domain E1-E2_ATPase PF00122.20 EEQ28750.1 - 3.4e-36 124.5 1.6 3.4e-36 124.5 1.6 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EEQ28750.1 - 3.1e-24 84.9 0.0 5.4e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EEQ28750.1 - 2.8e-06 26.9 0.2 1.1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF1774 PF08611.10 EEQ28750.1 - 0.38 11.1 4.1 0.096 13.0 0.4 1.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) LptF_LptG PF03739.14 EEQ28750.1 - 0.41 9.4 10.9 0.023 13.5 5.3 1.7 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG TctB PF07331.11 EEQ28750.1 - 3.6 7.9 9.7 4.7 7.5 2.9 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Nup84_Nup100 PF04121.13 EEQ28751.1 - 1.2e-179 599.0 2.2 1.5e-179 598.6 2.2 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 HBM PF16591.5 EEQ28751.1 - 0.005 16.3 0.7 0.005 16.3 0.7 2.1 2 0 0 2 2 2 1 Helical bimodular sensor domain SDA1 PF05285.12 EEQ28751.1 - 0.048 13.1 14.7 0.073 12.5 14.7 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EEQ28751.1 - 8.2 4.5 18.5 15 3.7 18.5 1.3 1 0 0 1 1 1 0 Nop14-like family MTCP1 PF08991.10 EEQ28752.1 - 3.1e-21 75.3 14.5 1.3e-19 70.1 14.5 2.0 1 1 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EEQ28752.1 - 0.036 14.2 2.0 0.072 13.3 2.0 1.5 1 0 0 1 1 1 0 CHCH domain Rad60-SLD PF11976.8 EEQ28753.1 - 5.3e-20 71.0 0.3 6.1e-20 70.8 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EEQ28753.1 - 3.8e-11 42.6 0.2 4.3e-11 42.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Abhydrolase_6 PF12697.7 EEQ28755.1 - 1.2e-08 35.8 0.3 1.4e-08 35.6 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 EEQ28755.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Methyltransf_25 PF13649.6 EEQ28756.1 - 1.7e-10 41.5 0.0 3.8e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ28756.1 - 1.5e-06 28.8 0.0 3.7e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ28756.1 - 2e-05 24.5 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ28756.1 - 3.3e-05 24.6 0.0 4.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ28756.1 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ28756.1 - 0.0043 16.4 0.0 0.0059 16.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Isochorismatase PF00857.20 EEQ28757.1 - 7.1e-36 124.0 0.0 2e-35 122.6 0.1 1.7 2 0 0 2 2 2 1 Isochorismatase family Iso_dh PF00180.20 EEQ28757.1 - 8.1e-11 41.7 0.0 6.4e-07 28.8 0.0 2.4 2 1 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Methyltransf_31 PF13847.6 EEQ28759.1 - 4.9e-12 45.9 0.0 6.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ28759.1 - 4.1e-11 43.4 0.0 8.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ28759.1 - 6e-11 43.0 0.0 1.1e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ28759.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ28759.1 - 1.7e-06 28.6 0.0 3.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EEQ28759.1 - 0.0098 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 EEQ28759.1 - 0.097 12.0 0.0 0.28 10.5 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EEQ28759.1 - 0.13 11.7 0.0 0.99 8.9 0.0 2.3 3 0 0 3 3 3 0 Putative methyltransferase CheR PF01739.18 EEQ28759.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Aldedh PF00171.22 EEQ28761.1 - 3.7e-109 365.3 0.0 4.5e-109 365.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 EEQ28761.1 - 0.053 13.5 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Tubulin PF00091.25 EEQ28762.1 - 2.7e-67 226.8 0.0 5.7e-67 225.7 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EEQ28762.1 - 1.3e-43 148.2 0.1 2.1e-43 147.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EEQ28762.1 - 2.2e-06 28.0 0.0 6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EEQ28762.1 - 0.00086 18.6 0.0 0.034 13.3 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EEQ28762.1 - 0.0043 16.8 0.0 0.0093 15.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 EEQ28763.1 - 1.7e-16 59.8 0.1 1.4e-07 31.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.19 EEQ28763.1 - 0.29 11.8 0.1 0.29 11.8 0.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRM_3 PF08777.11 EEQ28763.1 - 0.3 11.2 8.8 1.1 9.3 0.0 3.6 3 1 1 4 4 4 0 RNA binding motif Pkinase PF00069.25 EEQ28764.1 - 1.2e-65 221.6 0.0 2.1e-65 220.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28764.1 - 3.2e-34 118.4 0.1 3.9e-33 114.8 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ28764.1 - 1.7e-07 30.4 0.1 2.9e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEQ28764.1 - 3.1e-06 26.7 0.2 2.1e-05 24.0 0.2 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EEQ28764.1 - 9.4e-05 22.4 2.8 0.0049 16.8 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EEQ28764.1 - 0.01 14.9 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EEQ28764.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Vta1_C PF18097.1 EEQ28764.1 - 0.16 11.7 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 Vta1 C-terminal domain RIO1 PF01163.22 EEQ28764.1 - 0.2 11.2 0.3 0.4 10.3 0.3 1.4 1 0 0 1 1 1 0 RIO1 family adh_short PF00106.25 EEQ28765.1 - 3.2e-22 78.9 0.2 5.2e-19 68.5 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ28765.1 - 4.8e-11 42.7 0.3 4.8e-10 39.4 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ28765.1 - 0.0011 18.9 0.2 0.0017 18.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Goodbye PF17109.5 EEQ28766.1 - 2.1e-30 105.7 0.3 8.6e-30 103.7 0.3 2.2 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain TPR_6 PF13174.6 EEQ28766.1 - 0.014 16.0 3.3 2.5 8.9 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MID_MedPIWI PF18296.1 EEQ28766.1 - 0.029 14.2 1.2 0.066 13.0 1.2 1.6 1 0 0 1 1 1 0 MID domain of medPIWI TPR_19 PF14559.6 EEQ28766.1 - 0.042 14.3 1.2 2.3 8.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-UBR PF02207.20 EEQ28766.1 - 0.86 9.8 3.5 1.5 9.0 3.5 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) SesA PF17107.5 EEQ28767.1 - 0.00047 20.3 0.0 0.012 15.8 0.0 2.4 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases VIT PF08487.10 EEQ28768.1 - 5.3e-34 116.8 0.1 1.1e-33 115.8 0.1 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EEQ28768.1 - 9.7e-24 84.1 0.0 1.6e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EEQ28768.1 - 1.5e-10 41.6 0.0 2.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EEQ28768.1 - 3.6e-07 30.0 0.0 8.3e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 EEQ28768.1 - 7.6e-07 29.8 0.0 4.6e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EEQ28768.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.9 EEQ28768.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 VWA-like domain (DUF2201) MU117 PF15474.6 EEQ28769.1 - 1.1e-15 58.2 9.9 1.5e-15 57.8 9.9 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family Kp4 PF09044.10 EEQ28769.1 - 0.028 14.5 7.8 0.051 13.7 7.8 1.4 1 0 0 1 1 1 0 Kp4 CAP59_mtransfer PF11735.8 EEQ28770.1 - 2e-71 240.5 0.0 2.9e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 LANC_like PF05147.13 EEQ28771.1 - 3.2e-15 55.6 0.0 6.8e-12 44.6 0.0 3.2 2 1 0 2 2 2 2 Lanthionine synthetase C-like protein Haem_oxygenas_2 PF14518.6 EEQ28771.1 - 0.026 14.3 0.0 0.08 12.7 0.0 1.7 1 1 0 1 1 1 0 Iron-containing redox enzyme CBF PF03914.17 EEQ28772.1 - 6.1e-55 185.9 0.3 6.1e-55 185.9 0.3 2.8 3 1 0 3 3 3 1 CBF/Mak21 family Adaptin_N PF01602.20 EEQ28772.1 - 0.00087 18.0 0.8 0.032 12.8 0.1 2.2 2 0 0 2 2 2 2 Adaptin N terminal region Prok-E2_C PF14459.6 EEQ28772.1 - 0.07 13.3 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family C tRNA-synt_2b PF00587.25 EEQ28773.1 - 3.7e-29 102.0 0.0 1e-28 100.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EEQ28773.1 - 1.6e-09 37.8 0.0 4.3e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Prefoldin PF02996.17 EEQ28774.1 - 1.3e-22 80.0 0.0 1.6e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit KH_1 PF00013.29 EEQ28775.1 - 1.6e-05 24.6 0.0 0.0032 17.3 0.0 2.5 2 0 0 2 2 2 2 KH domain Invas_SpaK PF03519.14 EEQ28775.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Invasion protein B family SUIM_assoc PF16619.5 EEQ28775.1 - 0.34 11.0 3.2 0.49 10.5 0.2 2.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 CHCH PF06747.13 EEQ28776.1 - 6.8e-06 26.1 16.5 0.0002 21.4 10.5 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 EEQ28776.1 - 4.4e-05 23.4 10.2 0.00062 19.7 7.3 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 EEQ28776.1 - 0.028 14.7 8.2 0.5 10.7 1.5 3.0 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Kre28 PF17097.5 EEQ28776.1 - 0.071 12.1 0.0 0.071 12.1 0.0 1.1 1 0 0 1 1 1 0 Spindle pole body component COX6B PF02297.17 EEQ28776.1 - 0.42 10.9 11.9 3.2 8.0 6.3 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 EEQ28776.1 - 2.6 8.1 13.5 8.5 6.5 0.7 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CAP PF00188.26 EEQ28777.1 - 3.3e-18 66.7 7.0 4.4e-18 66.3 7.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PPTA PF01239.22 EEQ28777.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat DUF2784 PF10861.8 EEQ28777.1 - 0.62 10.1 3.6 8.9 6.4 2.4 2.3 2 0 0 2 2 2 0 Protein of Unknown function (DUF2784) Thioredox_DsbH PF03190.15 EEQ28778.1 - 1.2e-68 230.2 0.0 3e-68 228.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EEQ28778.1 - 0.00018 21.6 0.0 0.00062 19.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Glyco_hydro_9 PF00759.19 EEQ28778.1 - 0.025 14.0 0.1 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Glyco_hydro_76 PF03663.14 EEQ28778.1 - 0.049 13.1 0.2 0.4 10.1 0.1 2.0 1 1 0 2 2 2 0 Glycosyl hydrolase family 76 SPESP1 PF15754.5 EEQ28778.1 - 0.052 12.7 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 WD40 PF00400.32 EEQ28779.1 - 4.4e-17 62.1 15.7 0.0049 17.7 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ28779.1 - 0.00037 20.7 0.0 5.2 7.4 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Reg_prop PF07494.11 EEQ28779.1 - 0.0069 16.5 0.1 1.2 9.6 0.0 3.3 3 0 0 3 3 3 1 Two component regulator propeller DUF1513 PF07433.11 EEQ28779.1 - 0.04 13.0 0.1 0.2 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Nup160 PF11715.8 EEQ28779.1 - 0.12 11.0 0.1 0.36 9.4 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EEQ28779.1 - 0.12 11.0 0.0 0.38 9.4 0.0 1.7 1 1 0 1 1 1 0 Nup133 N terminal like LSM14 PF12701.7 EEQ28780.1 - 9.4e-26 89.7 0.0 1.7e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EEQ28780.1 - 5.2e-19 69.1 3.6 5.2e-19 69.1 3.6 3.3 3 0 0 3 3 3 1 FDF domain SM-ATX PF14438.6 EEQ28780.1 - 0.00016 21.7 0.1 0.00055 20.0 0.0 1.9 2 0 0 2 2 2 1 Ataxin 2 SM domain GRP PF07172.11 EEQ28780.1 - 4.7 8.0 26.0 20 6.0 18.0 2.7 2 0 0 2 2 2 0 Glycine rich protein family ACBP PF00887.19 EEQ28781.1 - 4.6e-22 78.0 0.0 4.6e-22 78.0 0.0 2.5 2 1 0 2 2 2 1 Acyl CoA binding protein Sigma70_ner PF04546.13 EEQ28781.1 - 0.081 12.8 7.9 0.04 13.8 5.9 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region TraP PF07296.11 EEQ28781.1 - 0.14 11.3 0.8 0.24 10.5 0.8 1.3 1 0 0 1 1 1 0 TraP protein CDC45 PF02724.14 EEQ28781.1 - 0.34 9.1 9.4 0.49 8.6 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EEQ28781.1 - 0.37 10.1 10.3 0.56 9.5 10.3 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EEQ28781.1 - 0.62 8.1 9.9 0.87 7.6 9.5 1.5 2 0 0 2 2 2 0 DNA polymerase phi PilJ PF13675.6 EEQ28781.1 - 0.73 9.9 5.1 1.3 9.1 2.9 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sporozoite_P67 PF05642.11 EEQ28781.1 - 1.3 7.0 4.2 1.7 6.6 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 EEQ28781.1 - 1.5 6.9 11.0 1.9 6.6 11.0 1.2 1 0 0 1 1 1 0 Nop14-like family Glyco_transf_15 PF01793.16 EEQ28782.1 - 3e-116 388.2 7.5 3.6e-116 388.0 7.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 EEQ28783.1 - 3.4e-32 112.3 2.7 3.5e-32 112.3 0.4 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EEQ28783.1 - 1e-23 84.3 2.2 1e-23 84.3 2.2 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GATase_5 PF13507.6 EEQ28784.1 - 5.6e-98 327.2 0.0 9.2e-98 326.5 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EEQ28784.1 - 7.8e-39 133.3 0.5 6.4e-25 88.1 0.2 2.6 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EEQ28784.1 - 7.5e-32 109.7 0.0 1.3e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EEQ28784.1 - 3.4e-21 75.5 0.0 1.1e-20 73.9 0.0 2.0 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain MFS_1 PF07690.16 EEQ28785.1 - 5.4e-39 134.1 25.8 5.4e-39 134.1 25.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ28785.1 - 7.2e-07 28.0 3.9 1e-06 27.5 2.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3169 PF11368.8 EEQ28785.1 - 0.037 13.5 4.8 2.4 7.6 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3169) zf-C3H1 PF10650.9 EEQ28786.1 - 1.2e-08 34.5 0.2 2.3e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain Myosin_head PF00063.21 EEQ28787.1 - 1.3e-257 856.5 0.0 1.3e-257 856.5 0.0 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) Isy1 PF06246.12 EEQ28787.1 - 2.6e-84 282.8 0.2 2.6e-84 282.8 0.2 9.7 4 3 1 6 6 6 1 Isy1-like splicing family Myosin_tail_1 PF01576.19 EEQ28787.1 - 3.5e-16 58.3 271.1 1.1e-11 43.4 117.7 6.6 1 1 1 3 3 3 2 Myosin tail Myosin_N PF02736.19 EEQ28787.1 - 2.3e-08 33.7 0.5 6e-08 32.4 0.5 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ADIP PF11559.8 EEQ28787.1 - 0.0056 16.8 11.4 0.0056 16.8 11.4 17.4 4 3 13 18 18 18 3 Afadin- and alpha -actinin-Binding AAA_22 PF13401.6 EEQ28787.1 - 0.53 10.6 0.0 0.53 10.6 0.0 5.0 4 1 1 5 5 5 0 AAA domain MMR_HSR1 PF01926.23 EEQ28788.1 - 1.6e-12 47.5 0.0 3.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ28788.1 - 5.6e-06 26.4 0.0 1.3e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EEQ28788.1 - 0.00025 20.6 0.2 0.00074 19.1 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 EEQ28788.1 - 0.011 16.3 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EEQ28788.1 - 0.027 14.0 0.0 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 EEQ28788.1 - 0.042 12.8 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Septin PF00735.18 EEQ28788.1 - 0.05 12.9 0.0 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Septin Arf PF00025.21 EEQ28788.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family HCO3_cotransp PF00955.21 EEQ28789.1 - 2.2e-66 224.8 12.2 1.3e-37 129.8 0.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family PI3Ka PF00613.20 EEQ28790.1 - 5.6e-59 198.7 0.1 9e-59 198.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EEQ28790.1 - 8.5e-46 156.8 0.0 1.2e-30 107.1 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EEQ28790.1 - 6.8e-33 113.5 0.0 1.1e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 EEQ28791.1 - 7.5e-33 112.7 0.0 2.9e-32 110.8 0.0 2.1 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EEQ28791.1 - 3.3e-15 55.9 0.1 1e-14 54.3 0.1 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4336 PF14234.6 EEQ28792.1 - 3e-16 59.5 0.1 6.8e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) IL4_i_Ig PF18258.1 EEQ28793.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain MARVEL PF01284.23 EEQ28794.1 - 3.7e-17 62.7 10.1 4.5e-17 62.4 10.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 EEQ28794.1 - 0.075 12.6 2.9 0.15 11.6 3.1 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Metallophos PF00149.28 EEQ28795.1 - 1.5e-12 48.5 0.0 2.9e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEQ28795.1 - 3.4e-06 27.4 0.0 6.3e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ThiF PF00899.21 EEQ28796.1 - 5.9e-42 143.7 0.0 9.2e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EEQ28796.1 - 0.0016 18.7 1.6 0.044 14.0 1.6 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EEQ28796.1 - 0.0058 16.9 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EEQ28796.1 - 0.058 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EEQ28796.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Melibiase_2 PF16499.5 EEQ28796.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A Abhydrolase_1 PF00561.20 EEQ28797.1 - 3.8e-45 154.5 0.1 1.2e-44 152.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EEQ28797.1 - 0.00084 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Gly_transf_sug PF04488.15 EEQ28799.1 - 1.8e-13 50.9 0.0 3.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Trypan_PARP PF05887.11 EEQ28799.1 - 0.00014 21.8 7.4 0.00023 21.2 7.4 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 EEQ28799.1 - 0.026 15.0 7.1 0.043 14.3 7.1 1.3 1 0 0 1 1 1 0 TonB polyproline region Pkinase PF00069.25 EEQ28800.1 - 1.2e-63 214.9 0.0 1.5e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28800.1 - 5.4e-34 117.6 0.0 7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ28800.1 - 0.00061 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EEQ28800.1 - 0.029 14.3 0.1 0.072 13.0 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EEQ28800.1 - 0.049 13.0 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEQ28800.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATP-synt_C PF00137.21 EEQ28801.1 - 1.3e-20 73.4 34.9 5.4e-18 65.1 14.4 2.8 2 1 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 EEQ28802.1 - 6.1e-70 236.0 0.0 1e-50 172.9 0.0 3.0 2 1 1 3 3 3 2 CNH domain PH_5 PF15405.6 EEQ28802.1 - 3.3e-39 134.1 0.0 7.4e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EEQ28802.1 - 1.1e-37 130.0 0.0 2e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EEQ28802.1 - 3e-13 49.6 0.0 6.6e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 EEQ28802.1 - 0.17 11.7 0.1 0.53 10.1 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Septin PF00735.18 EEQ28803.1 - 5.6e-101 337.5 0.3 9.1e-101 336.8 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EEQ28803.1 - 0.00084 19.4 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EEQ28803.1 - 0.019 15.1 1.8 1.1 9.3 0.0 3.1 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 EEQ28803.1 - 0.032 13.8 0.3 1.8 8.1 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain EB1 PF03271.17 EEQ28803.1 - 0.32 11.3 4.5 3.5 7.9 1.3 2.8 2 0 0 2 2 2 0 EB1-like C-terminal motif WD40 PF00400.32 EEQ28804.1 - 9.8e-05 23.1 0.0 0.89 10.5 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ28804.1 - 0.0023 18.2 0.0 0.91 9.9 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ28804.1 - 0.035 13.1 0.2 0.15 10.9 0.1 1.8 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EEQ28804.1 - 0.085 12.2 0.0 0.69 9.2 0.0 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.22 EEQ28805.1 - 1.3e-19 69.8 0.4 4.6e-19 68.0 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ28805.1 - 1.5e-05 25.0 0.0 4.6e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EEQ28805.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLIC PF05783.11 EEQ28806.1 - 3.5e-29 102.0 0.6 8.4e-17 61.1 0.0 4.1 4 1 0 4 4 4 3 Dynein light intermediate chain (DLIC) Peptidase_S9 PF00326.21 EEQ28807.1 - 4.7e-49 166.7 0.4 9.6e-49 165.7 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.12 EEQ28807.1 - 1.7e-08 34.1 0.7 0.16 11.9 0.1 4.1 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 EEQ28807.1 - 0.06 12.1 0.1 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain APH PF01636.23 EEQ28808.1 - 6.2e-13 49.2 0.0 1.4e-12 48.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ28808.1 - 0.00077 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EEQ28808.1 - 0.063 12.1 0.0 0.5 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 EEQ28808.1 - 0.26 10.6 0.0 18 4.6 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Peptidase_C12 PF01088.21 EEQ28809.1 - 1.3e-49 168.8 0.0 1.6e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Y_phosphatase3 PF13350.6 EEQ28810.1 - 2.9e-50 171.4 0.0 3.2e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EEQ28810.1 - 0.0047 16.5 0.0 0.0061 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EEQ28810.1 - 0.0073 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Spermine_synth PF01564.17 EEQ28811.1 - 0.12 11.8 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Methyltransf_30 PF05430.11 EEQ28811.1 - 0.12 12.2 0.0 0.42 10.5 0.0 1.8 1 1 1 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase DUF2052 PF09747.9 EEQ28812.1 - 2.5e-21 76.7 18.2 1.1e-10 41.9 0.6 2.1 1 1 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.14 EEQ28812.1 - 3.9 7.2 7.1 16 5.2 7.1 2.0 1 1 0 1 1 1 0 Pox virus Ag35 surface protein tRNA-synt_1d PF00750.19 EEQ28813.1 - 6.6e-64 216.1 0.1 1.3e-63 215.1 0.1 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EEQ28813.1 - 6.5e-30 103.7 1.0 9.6e-30 103.2 0.2 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain GST_N PF02798.20 EEQ28814.1 - 1.5e-11 44.5 0.1 2.4e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ28814.1 - 1.1e-08 35.4 0.1 2.5e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EEQ28814.1 - 1.6e-07 31.5 0.1 3.2e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEQ28814.1 - 1.8e-06 28.0 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ28814.1 - 3e-06 27.3 0.0 6.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ28814.1 - 2.5e-05 24.2 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EEQ28814.1 - 0.021 15.4 0.0 0.038 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Response_reg PF00072.24 EEQ28815.1 - 3.8e-21 75.3 0.0 2.7e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain SH3_1 PF00018.28 EEQ28817.1 - 2.7e-09 36.5 0.1 5.2e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ28817.1 - 4.7e-07 29.6 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ28817.1 - 4.9e-06 26.1 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 EEQ28817.1 - 0.09 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 SH3 domain TMEM220 PF15071.6 EEQ28817.1 - 0.42 11.4 3.7 0.52 11.1 2.3 1.9 1 1 1 2 2 2 0 Transmembrane family 220, helix Dynactin_p22 PF07426.11 EEQ28818.1 - 1.5e-07 31.4 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Dynactin subunit p22 UBA_4 PF14555.6 EEQ28819.1 - 3.7e-13 49.1 0.2 6.9e-13 48.2 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain DUF5082 PF16888.5 EEQ28819.1 - 0.082 13.2 0.5 0.41 10.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ApoC-I PF04691.12 EEQ28819.1 - 3.8 7.5 5.6 4.8 7.2 0.6 2.5 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) AMP-binding PF00501.28 EEQ28820.1 - 3.7e-60 203.7 0.1 8.4e-60 202.5 0.1 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ28820.1 - 4.6e-13 50.0 0.4 1.3e-12 48.5 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 EEQ28821.1 - 1.5e-52 178.6 0.0 2.1e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28821.1 - 4.7e-26 91.6 0.3 6e-25 88.0 0.3 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ28821.1 - 0.0025 17.2 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ28821.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EEQ28821.1 - 0.14 11.8 0.3 0.65 9.6 0.2 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EEQ28821.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arm-DNA-bind_5 PF17293.2 EEQ28822.1 - 0.028 14.8 0.1 0.4 11.1 0.1 2.1 2 0 0 2 2 2 0 Arm DNA-binding domain Bot1p PF12298.8 EEQ28823.1 - 5.7e-59 199.2 0.3 5.7e-59 199.2 0.3 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein RRM_1 PF00076.22 EEQ28824.1 - 1.7e-17 63.0 0.0 2.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EEQ28824.1 - 1.3e-06 28.9 7.6 1.3e-06 28.9 7.6 4.0 4 0 0 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 WD40 PF00400.32 EEQ28825.1 - 3.1e-16 59.5 5.0 2.9e-06 27.9 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ28825.1 - 3.3e-06 27.3 0.0 0.14 12.5 0.0 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ28825.1 - 0.044 12.8 0.0 0.82 8.6 0.0 2.3 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PUL PF08324.11 EEQ28826.1 - 8.6e-71 238.4 0.1 1.2e-70 237.9 0.1 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EEQ28826.1 - 1.2e-44 151.2 0.3 6e-44 148.9 0.1 2.2 1 1 1 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EEQ28826.1 - 3.4e-30 103.7 16.5 1.5e-06 28.8 0.0 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat Rotamase_2 PF13145.6 EEQ28826.1 - 0.13 13.1 0.6 1.1 10.1 0.1 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain YjeF_N PF03853.15 EEQ28827.1 - 4.3e-37 127.6 0.0 5.1e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 EEQ28827.1 - 0.19 11.8 0.1 0.34 11.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Ribosomal_S16 PF00886.19 EEQ28828.1 - 9.1e-24 83.3 0.1 1.9e-23 82.3 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S16 Pox_RNA_pol PF03293.14 EEQ28829.1 - 0.41 10.4 2.9 0.87 9.3 2.9 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit EB PF01683.18 EEQ28829.1 - 3.2 8.1 15.6 2.3 8.6 3.6 2.6 2 0 0 2 2 2 0 EB module RRM_1 PF00076.22 EEQ28830.1 - 1.7e-15 56.6 0.1 2.1e-13 49.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ28830.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif CH PF00307.31 EEQ28831.1 - 2.6e-43 146.6 0.8 1.2e-23 83.4 0.0 3.7 3 1 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EEQ28831.1 - 6.7e-26 90.2 0.2 1.8e-25 88.8 0.2 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EEQ28831.1 - 1.4e-08 34.4 0.1 8.1e-07 28.8 0.0 2.8 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_6 PF13405.6 EEQ28831.1 - 0.0014 18.4 0.0 0.0079 16.1 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EEQ28831.1 - 0.01 15.7 0.2 0.046 13.6 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair Spectrin PF00435.21 EEQ28831.1 - 0.013 16.0 10.0 0.77 10.3 0.0 3.0 3 0 0 3 3 3 0 Spectrin repeat SKA1 PF07160.12 EEQ28831.1 - 0.018 14.9 0.8 0.018 14.9 0.8 1.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 EF-hand_1 PF00036.32 EEQ28831.1 - 0.019 14.5 0.0 0.24 11.0 0.0 2.6 2 0 0 2 2 2 0 EF hand FliG_N PF14842.6 EEQ28831.1 - 0.2 12.2 3.2 3.9 8.1 0.1 3.2 2 1 1 3 3 3 0 FliG N-terminal domain EF-hand_7 PF13499.6 EEQ28831.1 - 0.68 10.4 4.4 0.94 10.0 0.2 3.0 3 0 0 3 3 3 0 EF-hand domain pair G-alpha PF00503.20 EEQ28833.1 - 8.6e-120 400.1 1.3 1e-119 399.9 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EEQ28833.1 - 1.6e-15 57.0 1.1 2.5e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EEQ28833.1 - 6.2e-05 22.7 0.0 0.00027 20.7 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EEQ28833.1 - 0.0011 18.3 3.0 0.052 12.9 0.0 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EEQ28833.1 - 0.013 15.7 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EEQ28833.1 - 0.019 14.7 0.1 0.051 13.3 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EEQ28833.1 - 0.026 13.7 0.1 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain GTP_EFTU PF00009.27 EEQ28833.1 - 0.061 12.9 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 EEQ28833.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 EEQ28833.1 - 0.1 12.0 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EEQ28833.1 - 0.14 12.2 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Use1 PF09753.9 EEQ28834.1 - 2.9e-10 40.3 4.8 3e-09 37.0 4.8 2.2 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF892 PF05974.12 EEQ28834.1 - 0.14 12.2 0.3 0.14 12.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Acetyltransf_1 PF00583.25 EEQ28835.1 - 6.5e-07 29.6 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ28835.1 - 1.6e-06 28.1 0.0 1.5e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ28835.1 - 0.00039 20.8 0.0 0.00084 19.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 EEQ28839.1 - 5.1e-93 312.0 0.0 6.7e-93 311.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ28839.1 - 4.2e-15 56.5 0.1 9.8e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nup188_C PF18378.1 EEQ28840.1 - 6.4e-115 383.9 0.1 6.1e-76 255.7 0.1 2.4 1 1 1 2 2 2 2 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EEQ28840.1 - 3.1e-79 267.0 0.0 1e-77 262.0 0.0 2.6 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 EEQ28841.1 - 1.4e-95 319.3 0.0 4.5e-95 317.6 0.0 1.8 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EEQ28841.1 - 1e-51 175.5 0.8 2.2e-47 161.4 0.1 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EEQ28841.1 - 6.3e-48 163.1 0.0 1.2e-47 162.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EEQ28841.1 - 0.00051 19.8 0.2 0.002 17.9 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 EEQ28841.1 - 0.0072 16.1 1.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 EEQ28841.1 - 0.0077 15.4 0.2 0.048 12.8 0.0 2.3 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EEQ28841.1 - 0.0083 15.6 0.1 0.052 13.0 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein Peripla_BP_2 PF01497.18 EEQ28841.1 - 0.11 12.0 0.0 0.48 9.9 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein FMN_dh PF01070.18 EEQ28841.1 - 0.12 11.4 0.2 0.54 9.2 0.0 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase BRCT_2 PF16589.5 EEQ28842.1 - 1.4e-06 28.6 0.0 2.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EEQ28842.1 - 4e-06 26.7 0.1 8.9e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EEQ28842.1 - 7.4e-06 26.3 0.1 1.4e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.15 EEQ28842.1 - 0.0075 16.3 0.0 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 WGR domain UPF1_Zn_bind PF09416.10 EEQ28843.1 - 1.5e-65 219.8 4.8 6.6e-65 217.7 0.9 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EEQ28843.1 - 1.4e-58 197.8 0.0 2.2e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEQ28843.1 - 5.1e-52 177.2 5.3 5.9e-30 104.9 0.3 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EEQ28843.1 - 1e-33 115.4 0.0 2.1e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EEQ28843.1 - 3.8e-12 46.3 0.2 3.2e-11 43.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ28843.1 - 3.6e-10 40.4 0.0 2.8e-09 37.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EEQ28843.1 - 2.2e-06 27.8 0.0 4.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EEQ28843.1 - 0.00018 21.4 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EEQ28843.1 - 0.0003 20.6 0.1 1.3 8.7 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EEQ28843.1 - 0.0016 17.8 0.2 0.036 13.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EEQ28843.1 - 0.025 14.8 0.0 0.084 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EEQ28843.1 - 0.026 14.3 0.3 0.056 13.2 0.2 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase PIF1 PF05970.14 EEQ28843.1 - 0.026 13.7 0.0 5.8 6.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase UvrD-helicase PF00580.21 EEQ28843.1 - 0.027 14.0 0.0 0.29 10.6 0.0 2.2 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 EEQ28843.1 - 0.046 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein TFIIF_alpha PF05793.12 EEQ28843.1 - 0.097 11.2 2.4 0.19 10.3 2.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GCIP PF13324.6 EEQ28843.1 - 0.12 12.0 1.2 0.23 11.0 1.2 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting AAA_16 PF13191.6 EEQ28843.1 - 0.12 12.7 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 EEQ28843.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.7 EEQ28843.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PBP1_TM PF14812.6 EEQ28843.1 - 0.64 10.4 5.0 1.7 9.1 5.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Brix PF04427.18 EEQ28844.1 - 6.1e-32 111.3 0.0 7.8e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain AhpC-TSA_2 PF13911.6 EEQ28845.1 - 1.3e-12 47.8 0.0 2.4e-12 47.0 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EEQ28845.1 - 3.7e-05 23.6 0.0 6.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family PI-PLC-X PF00388.19 EEQ28846.1 - 5.2e-58 194.7 0.0 1.3e-57 193.5 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EEQ28846.1 - 2.8e-42 143.7 0.1 5.5e-42 142.7 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EEQ28846.1 - 8.1e-05 22.9 0.0 0.00052 20.3 0.0 2.2 1 1 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 EEQ28846.1 - 0.00049 20.5 0.4 0.0013 19.2 0.4 1.8 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.6 EEQ28846.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 EEQ28846.1 - 0.13 12.7 0.0 0.66 10.5 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair Arif-1 PF06770.11 EEQ28848.1 - 0.054 13.2 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Mo-co_dimer PF03404.16 EEQ28849.1 - 6e-58 194.8 0.5 1.1e-57 193.9 0.5 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EEQ28849.1 - 5.7e-54 182.3 0.0 9.4e-54 181.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.21 EEQ28849.1 - 1.2e-27 96.7 0.0 1.2e-26 93.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EEQ28849.1 - 1.2e-17 63.9 0.0 2.5e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 EEQ28849.1 - 1.6e-17 63.7 0.0 2.9e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EEQ28849.1 - 0.0007 19.7 0.0 0.011 15.9 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Sec5 PF15469.6 EEQ28850.1 - 7.9e-37 126.9 0.0 3.2e-36 124.9 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 EEQ28850.1 - 0.00023 21.2 0.3 0.00081 19.4 0.3 2.0 1 0 0 1 1 1 1 Vps51/Vps67 GTP-bdg_M PF16360.5 EEQ28850.1 - 0.028 15.0 2.8 0.088 13.4 0.1 3.2 4 0 0 4 4 4 0 GTP-binding GTPase Middle Region DUF4111 PF13427.6 EEQ28850.1 - 0.063 13.5 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) DUF802 PF05650.11 EEQ28850.1 - 1.2 9.7 4.6 0.32 11.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Iso_dh PF00180.20 EEQ28851.1 - 9.1e-102 340.7 0.0 1.1e-101 340.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 EEQ28851.1 - 0.0066 16.3 0.0 0.016 15.0 0.0 1.6 2 0 0 2 2 2 1 Bacteriophage protein GP30.3 Eaf7 PF07904.13 EEQ28852.1 - 1.1e-22 80.4 0.1 8.6e-22 77.5 0.1 2.2 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 GCP_C_terminal PF04130.13 EEQ28853.1 - 1.7e-67 228.1 0.0 2.3e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EEQ28853.1 - 1e-33 117.3 0.0 6e-33 114.8 0.0 2.2 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal RdRP_4 PF02123.16 EEQ28853.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase rRNA_processing PF08524.11 EEQ28854.1 - 0.00043 20.3 8.1 0.00043 20.3 8.1 2.3 1 1 1 2 2 2 1 rRNA processing PGA_cap PF09587.10 EEQ28854.1 - 0.24 10.8 3.0 0.34 10.3 3.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF4210 PF13915.6 EEQ28855.1 - 4.8e-33 113.6 0.1 1.2e-32 112.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EEQ28855.1 - 1.4e-21 76.4 0.5 3.3e-21 75.2 0.2 1.9 2 0 0 2 2 2 1 Chromosome segregation during meiosis CAP_N PF01213.19 EEQ28856.1 - 5.8e-108 361.1 0.7 9.7e-108 360.4 0.0 1.7 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EEQ28856.1 - 4.6e-54 182.3 2.1 6.6e-54 181.8 2.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EEQ28856.1 - 0.075 12.8 3.7 2 8.2 3.1 2.3 1 1 1 2 2 2 0 Tubulin binding cofactor C BetaGal_dom2 PF10435.9 EEQ28856.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 PfkB PF00294.24 EEQ28857.1 - 1.2e-11 44.5 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribonucleas_3_3 PF14622.6 EEQ28859.1 - 1.2e-07 31.9 0.0 0.0019 18.3 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EEQ28859.1 - 1e-05 26.1 0.0 1.8e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EEQ28859.1 - 2.3e-05 25.0 0.0 4.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif WaaY PF06176.11 EEQ28860.1 - 0.041 13.5 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) TGBp3 PF02495.17 EEQ28860.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Triple gene block 3 BSP PF04450.12 EEQ28863.1 - 2e-64 217.2 0.0 2.4e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria CLASP_N PF12348.8 EEQ28864.1 - 6e-151 500.3 3.4 1.5e-91 306.0 0.0 3.0 3 0 0 3 3 3 2 CLASP N terminal Cnd1 PF12717.7 EEQ28864.1 - 9.9e-07 28.9 0.3 0.034 14.2 0.0 4.5 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EEQ28864.1 - 1.2e-05 25.1 0.0 3.5 8.2 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat HK97-gp10_like PF04883.12 EEQ28864.1 - 0.1 13.6 0.0 0.39 11.7 0.0 2.0 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Acetyltransf_8 PF13523.6 EEQ28865.1 - 1.3e-44 151.4 1.2 1.8e-44 151.0 1.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 EEQ28866.1 - 5.5e-89 298.5 32.6 1.2e-46 159.6 11.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ28866.1 - 6.6e-66 221.0 0.0 1.4e-32 113.0 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ28866.1 - 1e-15 57.8 5.3 5.6e-06 25.9 0.1 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EEQ28866.1 - 1.6e-10 40.4 0.3 0.0009 18.1 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 EEQ28866.1 - 4.2e-09 36.0 0.0 0.00078 19.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EEQ28866.1 - 2.2e-07 31.4 1.0 0.0083 16.5 0.3 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 EEQ28866.1 - 4.3e-07 30.3 0.2 0.0012 19.0 0.0 3.0 3 0 0 3 3 2 2 Helicase HerA, central domain AAA_22 PF13401.6 EEQ28866.1 - 5.7e-07 29.9 2.4 0.11 12.7 0.0 4.0 3 1 1 4 4 3 2 AAA domain AAA_15 PF13175.6 EEQ28866.1 - 8.2e-06 25.8 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ28866.1 - 5.7e-05 23.1 0.0 0.52 10.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EEQ28866.1 - 0.00011 22.1 0.9 2.4 7.9 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EEQ28866.1 - 0.00024 20.9 1.2 0.61 9.8 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EEQ28866.1 - 0.00084 19.9 0.0 0.54 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 EEQ28866.1 - 0.00095 18.4 0.0 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_23 PF13476.6 EEQ28866.1 - 0.0015 19.1 3.6 0.55 10.7 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EEQ28866.1 - 0.0019 18.3 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EEQ28866.1 - 0.0027 17.3 0.0 0.71 9.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 EEQ28866.1 - 0.0046 15.9 0.1 1.9 7.3 0.0 2.8 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 EEQ28866.1 - 0.0047 16.3 0.1 0.059 12.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EEQ28866.1 - 0.0055 16.0 0.0 1.3 8.2 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 EEQ28866.1 - 0.0066 16.5 0.0 6.2 6.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EEQ28866.1 - 0.012 15.2 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EEQ28866.1 - 0.017 14.9 0.1 7.1 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EEQ28866.1 - 0.018 14.0 6.0 0.43 9.5 0.0 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF3987) AAA_28 PF13521.6 EEQ28866.1 - 0.019 15.2 0.1 3.9 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EEQ28866.1 - 0.034 14.4 4.1 9.7 6.5 0.2 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EEQ28866.1 - 0.094 12.2 0.0 9.1 5.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EEQ28866.1 - 0.11 12.6 0.1 16 5.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EEQ28866.1 - 0.12 12.8 0.2 30 5.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF779 PF05610.11 EEQ28866.1 - 0.14 12.4 0.0 4.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF779) Rad17 PF03215.15 EEQ28866.1 - 0.19 11.7 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain FERM_N PF09379.10 EEQ28866.1 - 0.2 11.6 0.2 0.66 10.0 0.1 1.9 2 0 0 2 2 1 0 FERM N-terminal domain PRK PF00485.18 EEQ28866.1 - 0.21 11.3 0.8 16 5.2 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 EEQ28866.1 - 0.38 10.5 1.6 13 5.4 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein COX5A PF02284.16 EEQ28867.1 - 6.9e-39 132.0 0.8 9e-39 131.6 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.18 EEQ28868.1 - 1.4e-62 211.5 18.7 1.7e-62 211.2 18.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family AA_permease_2 PF13520.6 EEQ28870.1 - 4.5e-17 62.0 39.8 4.7e-13 48.7 27.8 2.2 1 1 1 2 2 2 2 Amino acid permease adh_short_C2 PF13561.6 EEQ28871.1 - 5.6e-63 212.6 0.0 7.3e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ28871.1 - 1.5e-51 174.7 0.2 1.8e-51 174.4 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ28871.1 - 1.8e-05 24.7 0.2 4.3e-05 23.5 0.2 1.5 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.14 EEQ28871.1 - 0.11 11.1 0.6 0.15 10.7 0.6 1.1 1 0 0 1 1 1 0 HI0933-like protein Epimerase PF01370.21 EEQ28871.1 - 0.15 11.5 0.1 0.25 10.7 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1996 PF09362.10 EEQ28872.1 - 3.2e-84 282.6 0.0 4.3e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.13 EEQ28872.1 - 0.032 14.6 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Y_phosphatase3 PF13350.6 EEQ28874.1 - 8.3e-47 160.1 0.0 9.6e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EEQ28874.1 - 5.7e-05 22.8 0.0 9.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EEQ28874.1 - 0.0054 16.3 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EEQ28874.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EEQ28874.1 - 0.18 11.9 0.1 1.4 9.1 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Myotub-related PF06602.14 EEQ28874.1 - 0.23 10.4 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain ABC_tran PF00005.27 EEQ28875.1 - 8.1e-67 224.0 0.1 2.5e-33 115.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ28875.1 - 7.2e-57 193.1 29.8 2.2e-44 152.2 16.8 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EEQ28875.1 - 1.5e-13 50.8 7.4 9e-05 22.0 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EEQ28875.1 - 6.1e-09 36.0 0.0 0.0017 18.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EEQ28875.1 - 2.7e-07 30.2 1.6 0.0036 17.0 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ28875.1 - 3.8e-07 30.5 1.1 0.066 13.5 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEQ28875.1 - 5.1e-07 30.2 0.2 0.021 15.2 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EEQ28875.1 - 2.5e-06 27.2 0.0 0.076 12.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain ABC_ATPase PF09818.9 EEQ28875.1 - 4.9e-06 25.6 1.7 0.12 11.1 0.1 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 EEQ28875.1 - 5.2e-05 23.1 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EEQ28875.1 - 0.00017 21.5 0.0 3 7.6 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 EEQ28875.1 - 0.00018 21.5 0.0 1.8 8.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 EEQ28875.1 - 0.0002 21.8 1.1 0.94 9.9 0.1 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EEQ28875.1 - 0.00027 21.0 0.0 0.05 13.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EEQ28875.1 - 0.00048 19.9 1.2 0.42 10.3 0.1 3.9 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.17 EEQ28875.1 - 0.0005 20.2 0.2 0.07 13.2 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 EEQ28875.1 - 0.001 19.2 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EEQ28875.1 - 0.0014 18.2 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 EEQ28875.1 - 0.0016 17.7 0.0 1 8.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 EEQ28875.1 - 0.0023 18.2 0.5 2.9 8.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EEQ28875.1 - 0.0024 18.1 3.1 5 7.4 0.4 4.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 EEQ28875.1 - 0.0024 17.1 0.0 0.88 8.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) G-alpha PF00503.20 EEQ28875.1 - 0.0045 16.2 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit RNA_helicase PF00910.22 EEQ28875.1 - 0.0055 17.1 0.0 0.49 10.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 EEQ28875.1 - 0.008 16.7 2.5 3.3 8.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain CbiA PF01656.23 EEQ28875.1 - 0.014 15.4 0.0 12 5.9 0.0 3.5 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EEQ28875.1 - 0.035 14.7 0.0 6.2 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EEQ28875.1 - 0.038 13.3 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Septin SRP54 PF00448.22 EEQ28875.1 - 0.067 12.8 0.3 4.4 6.9 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 EEQ28875.1 - 0.12 12.4 0.5 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family ATP-synt_ab PF00006.25 EEQ28875.1 - 0.12 12.0 0.7 4.2 7.0 0.0 3.1 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 EEQ28875.1 - 0.17 11.8 0.2 3.2 7.6 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF3632 PF12311.8 EEQ28876.1 - 6e-34 118.0 0.0 7.5e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) RIO1 PF01163.22 EEQ28878.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EEQ28879.1 - 0.0017 18.3 0.0 0.42 10.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ28879.1 - 0.056 13.0 0.1 0.37 10.3 0.1 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 EEQ28879.1 - 0.09 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S8 PF00082.22 EEQ28880.1 - 9e-45 153.2 0.4 1.5e-44 152.5 0.4 1.3 1 0 0 1 1 1 1 Subtilase family 2-Hacid_dh_C PF02826.19 EEQ28881.1 - 1.3e-48 164.7 0.0 8e-48 162.1 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ28881.1 - 6.4e-14 51.8 0.0 8.6e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 EEQ28881.1 - 0.00041 20.9 0.0 0.00076 20.0 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EEQ28881.1 - 0.00049 20.3 0.0 0.00076 19.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Asparaginase PF00710.20 EEQ28882.1 - 1.6e-56 190.9 0.0 2.5e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EEQ28882.1 - 3.1e-29 101.5 0.2 6.9e-29 100.4 0.2 1.6 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EEQ28882.1 - 2e-13 50.7 0.0 2e-08 34.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EEQ28882.1 - 8.4e-09 35.5 1.8 0.00018 21.8 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EEQ28882.1 - 1.1e-07 32.0 0.0 4.1e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ28882.1 - 4e-07 29.8 0.2 0.037 14.6 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EEQ28882.1 - 5.3e-06 26.9 0.8 0.0098 16.5 0.1 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) MTTB PF06253.11 EEQ28882.1 - 0.021 12.8 0.2 0.031 12.2 0.2 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) NmrA PF05368.13 EEQ28884.1 - 1.9e-07 30.9 0.3 2.1e-07 30.8 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family NAP PF00956.18 EEQ28885.1 - 3.4e-19 69.1 8.1 3.4e-19 69.1 8.1 2.2 2 1 1 3 3 3 1 Nucleosome assembly protein (NAP) Syntaxin-6_N PF09177.11 EEQ28886.1 - 2.6e-24 85.7 1.4 1.1e-23 83.6 0.1 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal APG17 PF04108.12 EEQ28886.1 - 0.00048 19.3 1.5 0.032 13.4 0.1 2.1 2 0 0 2 2 2 2 Autophagy protein Apg17 SNARE PF05739.19 EEQ28886.1 - 0.00063 19.7 0.9 0.0014 18.6 0.9 1.6 1 0 0 1 1 1 1 SNARE domain DUF3618 PF12277.8 EEQ28886.1 - 0.017 15.3 10.2 1.1 9.5 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) Vps51 PF08700.11 EEQ28886.1 - 0.018 15.1 2.6 7.6 6.7 0.0 3.2 3 0 0 3 3 3 0 Vps51/Vps67 ZnuA PF01297.17 EEQ28886.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic HMMR_N PF15905.5 EEQ28886.1 - 0.045 13.2 0.2 0.045 13.2 0.2 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal YtxH PF12732.7 EEQ28886.1 - 0.061 13.9 2.5 1.3 9.6 0.5 2.6 2 1 0 2 2 2 0 YtxH-like protein GCIP PF13324.6 EEQ28886.1 - 0.063 12.9 4.6 0.041 13.5 1.5 2.1 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting Peptidase_M75 PF09375.10 EEQ28886.1 - 0.067 12.7 0.2 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Imelysin DUF883 PF05957.13 EEQ28886.1 - 0.093 13.3 2.6 26 5.5 0.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF5089 PF17002.5 EEQ28886.1 - 0.3 11.0 3.1 0.13 12.2 0.5 1.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5089) HTH_25 PF13413.6 EEQ28886.1 - 0.38 10.6 2.5 0.82 9.6 0.2 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain Cnn_1N PF07989.11 EEQ28886.1 - 0.43 10.8 7.1 3.8 7.8 1.0 3.2 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 NPV_P10 PF05531.12 EEQ28886.1 - 0.68 10.4 8.2 1.3 9.6 0.9 3.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 EEQ28886.1 - 1.1 9.4 8.3 1.2 9.3 1.5 2.2 2 0 0 2 2 2 0 Tropomyosin like UPF0242 PF06785.11 EEQ28886.1 - 2 8.5 7.7 3.7 7.6 0.9 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Methyltransf_32 PF13679.6 EEQ28887.1 - 1.8e-23 83.3 0.4 3.4e-23 82.4 0.4 1.5 1 1 0 1 1 1 1 Methyltransferase domain PTR2 PF00854.21 EEQ28888.1 - 1.7e-77 260.9 4.8 1.7e-77 260.9 4.8 1.4 1 1 1 2 2 2 1 POT family Amb_V_allergen PF03913.13 EEQ28888.1 - 0.55 10.2 4.4 0.19 11.7 1.3 1.7 2 0 0 2 2 2 0 Amb V Allergen LCCL PF03815.19 EEQ28889.1 - 2.8e-19 69.0 0.3 4.9e-19 68.2 0.3 1.3 1 0 0 1 1 1 1 LCCL domain Rxt3 PF08642.10 EEQ28889.1 - 0.037 14.8 0.0 0.082 13.7 0.0 1.5 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Pkinase PF00069.25 EEQ28890.1 - 1.2e-05 24.8 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28890.1 - 0.0072 15.6 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2012 PF09430.10 EEQ28891.1 - 4.8e-23 81.6 0.0 6.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 EEQ28891.1 - 0.034 13.7 0.1 0.077 12.5 0.1 1.6 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein AMP-binding PF00501.28 EEQ28892.1 - 4.3e-76 256.2 0.0 5.5e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cys_Met_Meta_PP PF01053.20 EEQ28893.1 - 4.8e-141 469.7 0.0 7.4e-141 469.1 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EEQ28893.1 - 2.7e-12 46.7 0.3 4.8e-12 45.9 0.3 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EEQ28893.1 - 3.1e-09 36.5 0.1 4.5e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ28893.1 - 2.8e-08 33.1 0.1 4.5e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EEQ28893.1 - 6.9e-05 22.3 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EEQ28893.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Asparaginase_C PF17763.1 EEQ28893.1 - 0.074 13.3 0.1 0.34 11.1 0.0 2.1 3 0 0 3 3 3 0 Glutaminase/Asparaginase C-terminal domain Sulfotransfer_4 PF17784.1 EEQ28894.1 - 9.9e-69 231.4 0.0 1.2e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EEQ28894.1 - 4.6e-06 27.2 0.4 0.03 14.7 0.0 2.7 2 1 0 3 3 3 2 Sulfotransferase family MARVEL PF01284.23 EEQ28895.1 - 2.9e-16 59.8 18.3 3.6e-16 59.5 18.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain TNFR_16_TM PF18422.1 EEQ28895.1 - 0.02 14.8 0.5 0.055 13.4 0.5 1.8 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain EF-hand_4 PF12763.7 EEQ28896.1 - 2.3e-38 130.3 0.0 9.7e-16 57.6 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EEQ28896.1 - 1.2e-08 35.3 0.0 3.7e-05 24.1 0.1 4.1 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EEQ28896.1 - 1.5e-06 27.3 0.5 0.022 14.3 0.0 5.4 6 0 0 6 6 5 1 EF hand UBA PF00627.31 EEQ28896.1 - 2.2e-05 24.3 0.1 4.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF812 PF05667.11 EEQ28896.1 - 2.5e-05 23.4 9.5 5.4e-05 22.3 9.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) EF-hand_6 PF13405.6 EEQ28896.1 - 6.1e-05 22.6 1.3 9.3 6.5 0.0 6.1 6 0 0 6 6 6 0 EF-hand domain TMF_TATA_bd PF12325.8 EEQ28896.1 - 0.011 16.0 3.4 0.011 16.0 3.4 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding EF-hand_8 PF13833.6 EEQ28896.1 - 0.011 15.6 0.5 0.13 12.1 0.1 3.1 4 0 0 4 4 3 0 EF-hand domain pair BicD PF09730.9 EEQ28896.1 - 0.019 13.4 24.3 0.38 9.1 24.2 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D GAS PF13851.6 EEQ28896.1 - 0.032 13.6 28.4 0.21 10.9 9.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EEQ28896.1 - 0.06 12.2 28.3 0.39 9.6 5.0 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.8 EEQ28896.1 - 0.061 12.6 30.7 0.02 14.2 8.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FPP PF05911.11 EEQ28896.1 - 0.32 9.1 19.5 0.57 8.3 19.5 1.4 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Macoilin PF09726.9 EEQ28896.1 - 0.9 8.0 18.1 0.029 13.0 8.1 2.3 2 0 0 2 2 2 0 Macoilin family LPP PF04728.13 EEQ28896.1 - 0.99 9.8 9.0 0.97 9.9 0.7 3.0 2 1 0 2 2 2 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 EEQ28896.1 - 1 9.4 28.1 0.61 10.1 10.4 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 EEQ28896.1 - 2 8.6 34.4 1.5 9.0 12.6 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 EEQ28896.1 - 2.3 8.3 31.4 0.095 12.8 20.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EEQ28896.1 - 3.5 7.7 11.2 1.8 8.6 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MbeD_MobD PF04899.12 EEQ28896.1 - 4.3 7.5 15.0 5.6 7.1 1.1 4.3 2 1 2 4 4 4 0 MbeD/MobD like Tup_N PF08581.10 EEQ28896.1 - 6 7.2 16.5 0.071 13.4 2.1 2.9 2 1 1 3 3 3 0 Tup N-terminal Fib_alpha PF08702.10 EEQ28896.1 - 6.9 6.8 16.7 0.067 13.4 4.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IFT57 PF10498.9 EEQ28896.1 - 7.4 5.4 19.2 50 2.7 19.2 2.1 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Seryl_tRNA_N PF02403.22 EEQ28896.1 - 8.2 6.7 26.0 0.65 10.3 6.5 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tubulin PF00091.25 EEQ28897.1 - 5.5e-65 219.3 0.0 8.1e-65 218.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EEQ28897.1 - 3.4e-47 159.7 0.1 6.9e-47 158.7 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EEQ28897.1 - 0.0063 16.2 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 EEQ28897.1 - 0.1 12.5 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) POTRA_3 PF17287.2 EEQ28897.1 - 0.3 10.6 0.8 8.9 5.9 0.1 2.4 2 0 0 2 2 2 0 POTRA domain Pga1 PF10333.9 EEQ28898.1 - 0.00074 19.4 0.0 0.0009 19.1 0.0 1.4 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Peptidase_M24 PF00557.24 EEQ28899.1 - 3.4e-41 141.3 0.0 5e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EEQ28899.1 - 6.6e-25 87.0 0.9 1.4e-24 85.9 0.4 1.9 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N_2 PF16189.5 EEQ28899.1 - 7.9e-22 78.1 0.2 2e-11 44.3 0.0 3.4 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 EEQ28899.1 - 2.9e-18 66.8 0.1 2e-17 64.1 0.0 2.3 2 1 1 3 3 3 1 Creatinase/Prolidase N-terminal domain Importin_rep_3 PF18806.1 EEQ28900.1 - 0.065 13.3 0.0 3 7.9 0.0 2.7 2 0 0 2 2 2 0 Importin 13 repeat MEF2_binding PF09047.10 EEQ28900.1 - 0.19 11.6 1.0 0.96 9.4 0.3 2.4 2 0 0 2 2 2 0 MEF2 binding SOR_SNZ PF01680.17 EEQ28902.1 - 7.8e-108 359.0 5.2 1.3e-107 358.2 5.2 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EEQ28902.1 - 3.4e-09 36.4 8.0 1.3e-07 31.2 0.1 2.7 3 1 1 4 4 4 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EEQ28902.1 - 0.0019 17.3 0.6 0.32 10.0 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EEQ28902.1 - 0.0023 17.4 0.2 0.031 13.7 0.0 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 EEQ28902.1 - 0.0039 17.2 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 EEQ28902.1 - 0.0083 15.3 0.0 0.35 10.0 0.0 2.4 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.17 EEQ28902.1 - 0.021 14.1 0.5 0.62 9.4 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase NanE PF04131.14 EEQ28902.1 - 0.024 13.8 0.8 0.26 10.5 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.24 EEQ28902.1 - 0.043 13.4 0.1 0.39 10.3 0.0 2.2 1 1 2 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Peptidase_S64 PF08192.11 EEQ28903.1 - 3.6e-08 32.4 0.0 5.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.6 EEQ28903.1 - 5.1e-05 24.2 0.0 0.0002 22.3 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.21 EEQ28903.1 - 0.0012 18.6 0.1 0.0026 17.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S32 PF05579.13 EEQ28903.1 - 0.0033 16.6 0.1 0.0066 15.7 0.1 1.4 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin PF00089.26 EEQ28903.1 - 0.097 12.5 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Trypsin Peptidase_S3 PF00944.19 EEQ28903.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Alphavirus core protein FUN14 PF04930.15 EEQ28904.1 - 2.9e-07 30.8 1.5 8.8e-07 29.3 1.5 1.8 1 1 0 1 1 1 1 FUN14 family ORC2 PF04084.14 EEQ28905.1 - 4.2e-98 328.3 0.0 8e-76 255.1 0.0 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 2 AT_hook PF02178.19 EEQ28905.1 - 6.5 7.0 10.9 2.2 8.4 7.1 2.4 2 0 0 2 2 2 0 AT hook motif ArgJ PF01960.18 EEQ28906.1 - 3.9e-150 499.8 0.1 4.5e-150 499.6 0.1 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.20 EEQ28907.1 - 3.6e-73 246.5 7.5 4.5e-73 246.2 7.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EEQ28907.1 - 2.2e-17 62.6 0.3 6e-17 61.2 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p Spc42p PF11544.8 EEQ28908.1 - 0.0016 18.4 5.7 0.016 15.2 5.7 2.8 1 0 0 1 1 1 1 Spindle pole body component Spc42p Sas6_CC PF18594.1 EEQ28908.1 - 0.11 12.2 0.3 0.11 12.2 0.3 3.1 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain ArAE_2_N PF10337.9 EEQ28908.1 - 0.23 10.5 5.7 0.2 10.7 0.3 2.4 1 1 1 2 2 2 0 Putative ER transporter, 6TM, N-terminal Allexi_40kDa PF05549.11 EEQ28908.1 - 2.1 7.8 9.4 0.93 9.0 6.4 2.0 1 1 0 1 1 1 0 Allexivirus 40kDa protein NOA36 PF06524.12 EEQ28908.1 - 2.7 7.2 16.4 5.6 6.2 16.4 1.5 1 0 0 1 1 1 0 NOA36 protein DUF3338 PF11819.8 EEQ28908.1 - 2.9 7.9 14.7 0.14 12.1 6.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3338) Promethin PF16015.5 EEQ28909.1 - 4.5e-28 97.3 16.4 6.2e-28 96.8 16.4 1.2 1 0 0 1 1 1 1 Promethin DUF1700 PF08006.11 EEQ28909.1 - 1.1 8.7 9.2 1.8 8.0 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF677 PF05055.12 EEQ28909.1 - 4.6 6.0 4.1 6.3 5.6 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) GFA PF04828.14 EEQ28910.1 - 2.5e-16 59.8 2.0 2.5e-16 59.8 2.0 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DNA_RNApol_7kD PF03604.13 EEQ28910.1 - 0.26 11.0 0.3 0.26 11.0 0.3 2.8 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit MUG113 PF13455.6 EEQ28911.1 - 1.5e-20 73.7 0.5 2.8e-20 72.8 0.5 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EEQ28911.1 - 2.9e-20 72.7 0.2 7.1e-20 71.5 0.2 1.6 1 0 0 1 1 1 1 T5orf172 domain tRNA-synt_2c PF01411.19 EEQ28912.1 - 1.2e-08 33.9 0.0 1.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EEQ28912.1 - 1.2e-05 25.2 0.4 2.1e-05 24.5 0.4 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.16 EEQ28913.1 - 1.9e-49 168.5 32.0 1.1e-40 139.7 26.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EEQ28913.1 - 3.8e-05 22.7 15.9 0.0017 17.3 3.2 2.7 2 1 1 3 3 3 2 MFS_1 like family OATP PF03137.20 EEQ28913.1 - 0.00014 20.4 7.4 0.00093 17.6 0.0 2.6 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EEQ28913.1 - 0.0002 19.9 3.4 0.0002 19.9 3.4 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_4 PF06779.14 EEQ28913.1 - 0.74 9.0 24.8 0.37 10.0 7.1 3.3 2 2 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB Trypsin_2 PF13365.6 EEQ28914.1 - 0.00065 20.6 0.0 0.0084 17.0 0.0 2.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S3 PF00944.19 EEQ28914.1 - 0.077 12.8 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Alphavirus core protein MFS_1 PF07690.16 EEQ28915.1 - 3.4e-41 141.3 50.3 2.7e-29 102.2 25.2 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EEQ28915.1 - 5.9e-12 44.8 17.1 8.3e-12 44.3 17.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Spore_III_AF PF09581.10 EEQ28915.1 - 0.078 13.0 0.3 0.21 11.6 0.3 1.7 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) MFS_1_like PF12832.7 EEQ28915.1 - 0.66 8.8 22.7 0.0093 14.9 11.9 2.8 3 1 0 3 3 3 0 MFS_1 like family OATP PF03137.20 EEQ28915.1 - 3 6.0 11.2 2.5 6.3 3.0 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family UDG PF03167.19 EEQ28916.1 - 0.059 13.4 0.0 0.58 10.1 0.0 2.1 1 1 0 1 1 1 0 Uracil DNA glycosylase superfamily DUF2284 PF10050.9 EEQ28916.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) FtsJ PF01728.19 EEQ28917.1 - 3.2e-15 56.7 0.0 4.5e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Zn_clus PF00172.18 EEQ28918.1 - 5.2e-08 32.9 10.2 1.4e-07 31.5 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EEQ28919.1 - 1.1e-15 57.6 0.0 5.2e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ28919.1 - 1.1e-11 44.8 0.2 1.8e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ28919.1 - 0.00045 20.2 0.2 0.0022 17.9 0.2 2.0 1 1 0 1 1 1 1 KR domain DFP PF04127.15 EEQ28919.1 - 0.0006 19.7 0.0 0.00095 19.0 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 EEQ28919.1 - 0.0094 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EEQ28919.1 - 0.093 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.22 EEQ28920.1 - 1.6e-39 135.9 0.0 1.6e-27 96.4 0.0 2.1 1 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EEQ28921.1 - 6.5e-31 107.6 0.1 8e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 EEQ28922.1 - 1.6e-62 211.5 0.0 1.3e-35 122.9 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EEQ28922.1 - 5.9e-37 127.4 0.0 1e-36 126.6 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EEQ28922.1 - 8.9e-07 29.2 0.0 2.8e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ28922.1 - 0.00069 20.5 0.1 0.0014 19.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy PF03171.20 EEQ28923.1 - 9.5e-13 48.5 0.0 1.9e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EEQ28923.1 - 2.4e-09 38.0 0.0 3.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MinC_N PF05209.13 EEQ28923.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain ABC_membrane PF00664.23 EEQ28924.1 - 1e-96 323.8 31.6 2.8e-48 165.0 7.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ28924.1 - 2.7e-68 228.7 0.2 5.9e-34 117.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EEQ28924.1 - 3.6e-12 46.2 2.1 0.0017 17.8 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EEQ28924.1 - 2.8e-07 30.6 0.0 0.034 13.8 0.4 3.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 EEQ28924.1 - 4e-07 30.6 1.1 0.019 15.3 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EEQ28924.1 - 5e-06 26.8 1.3 0.064 13.5 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EEQ28924.1 - 1.9e-05 24.3 1.5 0.17 11.7 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EEQ28924.1 - 2.3e-05 24.4 0.4 0.12 12.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EEQ28924.1 - 2.6e-05 24.2 0.1 0.49 10.3 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 EEQ28924.1 - 7.9e-05 23.2 0.8 0.056 13.9 0.1 3.1 3 0 0 3 3 2 1 AAA domain PRK PF00485.18 EEQ28924.1 - 0.00014 21.7 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 EEQ28924.1 - 0.00038 20.2 0.3 5.6 6.6 0.0 3.7 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 EEQ28924.1 - 0.0007 18.9 0.1 0.29 10.4 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 EEQ28924.1 - 0.0014 19.2 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EEQ28924.1 - 0.0015 18.6 0.1 3.9 7.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EEQ28924.1 - 0.0019 18.3 0.0 0.41 10.7 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain ABC_ATPase PF09818.9 EEQ28924.1 - 0.0028 16.5 2.9 0.023 13.5 0.1 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class ATP-synt_ab PF00006.25 EEQ28924.1 - 0.0033 17.1 0.3 2.1 7.9 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 EEQ28924.1 - 0.0042 17.5 1.9 5.7 7.4 0.1 4.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EEQ28924.1 - 0.0044 17.1 0.0 9.1 6.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EEQ28924.1 - 0.0052 17.0 1.0 3.1 8.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 EEQ28924.1 - 0.0072 15.5 0.2 2.7 7.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 EEQ28924.1 - 0.01 15.8 0.1 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 EEQ28924.1 - 0.011 15.4 1.2 1.1 8.8 0.2 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EEQ28924.1 - 0.013 15.3 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EEQ28924.1 - 0.018 15.2 3.9 5.3 7.4 0.3 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 EEQ28924.1 - 0.019 14.2 0.0 4.3 6.4 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit Mg_chelatase PF01078.21 EEQ28924.1 - 0.024 14.0 0.0 1.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EEQ28924.1 - 0.03 14.7 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 EEQ28924.1 - 0.042 13.7 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 EEQ28924.1 - 0.048 13.8 0.0 7.2 6.7 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EEQ28924.1 - 0.049 13.8 0.0 16 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEQ28924.1 - 0.079 12.5 0.1 6.9 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EEQ28924.1 - 0.098 12.4 0.0 9.3 5.9 0.0 2.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Cys_Met_Meta_PP PF01053.20 EEQ28925.1 - 3.4e-109 364.9 0.0 8.8e-106 353.7 0.0 2.1 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEQ28925.1 - 1.8e-10 40.6 0.0 2.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ28925.1 - 1e-08 34.6 0.1 1.6e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ28925.1 - 1.5e-05 24.5 0.1 2.5e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EEQ28925.1 - 0.078 12.2 0.1 0.65 9.2 0.1 2.0 1 1 0 1 1 1 0 Beta-eliminating lyase ABC_membrane PF00664.23 EEQ28926.1 - 2.1e-101 339.2 35.4 1.2e-51 176.0 11.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ28926.1 - 1.1e-68 230.1 0.0 2.4e-33 115.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ28926.1 - 7.2e-15 55.0 0.0 0.00021 20.8 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EEQ28926.1 - 3.9e-07 30.6 2.7 0.031 14.7 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EEQ28926.1 - 1.3e-06 28.0 1.4 0.0068 16.1 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ28926.1 - 1.3e-06 28.4 0.1 0.013 15.4 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 EEQ28926.1 - 1.5e-06 28.5 0.4 0.2 11.9 0.0 3.7 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 EEQ28926.1 - 4.5e-06 25.7 2.9 0.097 11.5 0.2 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 EEQ28926.1 - 8.2e-06 25.7 0.7 0.46 10.2 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 EEQ28926.1 - 1.6e-05 24.9 0.9 0.35 10.6 0.0 3.9 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EEQ28926.1 - 3.6e-05 24.2 4.0 0.21 12.0 0.3 4.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EEQ28926.1 - 5e-05 23.2 0.0 0.082 12.6 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EEQ28926.1 - 0.0001 22.0 0.5 0.093 12.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EEQ28926.1 - 0.00023 21.1 0.2 0.44 10.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EEQ28926.1 - 0.00025 21.0 0.1 0.098 12.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 EEQ28926.1 - 0.00027 20.5 0.0 0.67 9.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EEQ28926.1 - 0.0013 19.3 0.4 1.9 9.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EEQ28926.1 - 0.0019 18.4 0.0 2 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EEQ28926.1 - 0.005 16.1 0.0 3.2 7.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 EEQ28926.1 - 0.01 15.6 0.0 4.8 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EEQ28926.1 - 0.011 15.9 3.8 6.8 7.0 0.5 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EEQ28926.1 - 0.013 16.0 3.3 1.5 9.3 0.0 3.5 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EEQ28926.1 - 0.016 15.6 0.0 4.1 7.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 EEQ28926.1 - 0.018 15.2 0.3 0.72 9.9 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain SRP54 PF00448.22 EEQ28926.1 - 0.019 14.6 0.2 7.3 6.2 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EEQ28926.1 - 0.039 14.2 0.4 7.4 6.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EEQ28926.1 - 0.053 13.4 0.1 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 EEQ28926.1 - 0.056 13.2 0.0 8.5 6.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SAA PF00277.18 EEQ28926.1 - 0.058 13.9 1.2 1.2 9.6 0.0 2.7 3 0 0 3 3 2 0 Serum amyloid A protein Cytidylate_kin PF02224.18 EEQ28926.1 - 0.079 12.7 0.1 4.7 6.9 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase G-alpha PF00503.20 EEQ28926.1 - 0.13 11.4 0.0 12 4.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 EEQ28926.1 - 0.17 11.6 0.3 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L39 PF00832.20 EEQ28928.1 - 2.3e-21 75.1 9.4 4.1e-21 74.3 9.4 1.4 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.19 EEQ28929.1 - 2.9e-28 97.7 0.5 4.8e-28 97.0 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EEQ28929.1 - 4e-25 87.8 0.3 9.3e-25 86.6 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DFF-C PF09033.10 EEQ28929.1 - 0.047 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Glyco_transf_22 PF03901.17 EEQ28930.1 - 1.7e-59 202.1 24.1 2.4e-59 201.6 24.1 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XPC-binding PF09280.11 EEQ28931.1 - 2.5e-24 84.8 17.8 4.3e-24 84.0 17.8 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EEQ28931.1 - 3.4e-22 78.0 3.9 2.1e-12 46.7 0.1 3.1 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 EEQ28931.1 - 5.2e-21 74.2 0.0 9.6e-21 73.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EEQ28931.1 - 3.4e-07 30.0 0.1 6e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EEQ28931.1 - 0.0011 18.7 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 EEQ28931.1 - 0.038 14.1 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1180 PF06679.12 EEQ28931.1 - 4.9 7.5 15.4 3 8.2 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Herpes_pp85 PF04637.12 EEQ28931.1 - 6.6 5.0 6.6 9.4 4.5 6.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3431 PF11913.8 EEQ28932.1 - 2.4e-73 246.5 1.2 1.3e-72 244.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) Aminotran_1_2 PF00155.21 EEQ28933.1 - 6.8e-35 120.9 0.0 3.7e-21 75.7 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ28933.1 - 7.4e-06 25.1 0.0 0.00083 18.4 0.0 2.5 3 0 0 3 3 3 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EEQ28933.1 - 9.5e-06 24.4 0.0 0.00067 18.3 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme PHO4 PF01384.20 EEQ28934.1 - 1.5e-124 415.4 17.0 1.7e-124 415.2 17.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family Alpha-2-MRAP_C PF06401.11 EEQ28934.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Pkinase PF00069.25 EEQ28936.1 - 2.1e-27 96.2 0.1 1.1e-26 93.8 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ28936.1 - 5.6e-15 55.3 0.0 1.4e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ28936.1 - 0.0003 19.7 0.0 0.00044 19.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEQ28936.1 - 0.042 13.8 0.1 0.065 13.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EEQ28936.1 - 0.047 13.3 0.2 0.072 12.7 0.2 1.3 1 0 0 1 1 1 0 RIO1 family adh_short PF00106.25 EEQ28937.1 - 2.4e-40 138.1 0.0 3.3e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ28937.1 - 2.1e-26 92.9 0.0 2.7e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EEQ28937.1 - 1.3e-06 28.0 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EEQ28937.1 - 3.6e-06 27.0 0.0 8.5e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 KR domain DASH_Duo1 PF08651.10 EEQ28937.1 - 0.097 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 PQ-loop PF04193.14 EEQ28938.1 - 8.4e-40 134.4 10.5 1.9e-20 72.4 0.8 2.6 2 0 0 2 2 2 2 PQ loop repeat NMN_transporter PF04973.12 EEQ28938.1 - 9.8 6.1 11.5 0.38 10.7 2.6 2.7 3 1 0 3 3 3 0 Nicotinamide mononucleotide transporter SGS PF05002.15 EEQ28939.1 - 1.6e-28 98.6 7.4 6.5e-28 96.7 7.4 2.1 1 1 0 1 1 1 1 SGS domain CS PF04969.16 EEQ28939.1 - 3.1e-18 66.5 0.0 6.7e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 EEQ28939.1 - 0.001 19.0 1.4 0.11 12.6 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ28939.1 - 0.0027 17.5 0.2 0.0027 17.5 0.2 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ28939.1 - 0.0033 17.1 0.4 0.01 15.5 0.4 1.9 1 0 0 1 1 1 1 TPR repeat CcmH PF03918.14 EEQ28939.1 - 0.13 11.5 0.3 0.29 10.4 0.3 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein SQHop_cyclase_C PF13243.6 EEQ28940.1 - 7.6e-46 156.7 0.2 5.9e-44 150.5 0.1 2.5 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EEQ28940.1 - 4.3e-45 154.0 0.9 9.8e-38 129.9 0.1 3.4 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EEQ28940.1 - 1.4e-32 111.1 4.1 4.6e-10 39.0 0.0 5.2 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EEQ28940.1 - 6.9e-06 25.6 0.7 0.071 12.4 0.1 4.0 3 1 1 4 4 4 3 Pectic acid lyase TED_complement PF07678.14 EEQ28940.1 - 0.0064 15.5 0.1 0.072 12.1 0.2 2.5 2 1 0 2 2 2 1 A-macroglobulin TED domain Ank_2 PF12796.7 EEQ28942.1 - 9.4e-27 93.4 0.3 5.3e-13 49.4 0.1 4.7 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEQ28942.1 - 1.6e-21 74.1 0.9 3.5e-06 26.9 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EEQ28942.1 - 3.9e-21 75.1 0.5 4.3e-08 33.6 0.1 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ28942.1 - 1.2e-17 63.7 1.0 9.7e-10 38.5 0.0 5.4 4 3 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EEQ28942.1 - 1.4e-14 53.8 0.7 1.1e-06 28.8 0.1 6.8 7 0 0 7 7 7 2 Ankyrin repeat TetR_C_24 PF17932.1 EEQ28942.1 - 0.0053 17.0 0.0 0.046 14.0 0.0 2.4 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain eIF-6 PF01912.18 EEQ28943.1 - 5.2e-79 264.2 0.9 7.3e-79 263.7 0.7 1.3 2 0 0 2 2 2 1 eIF-6 family SRR1 PF07985.12 EEQ28944.1 - 4.6e-15 55.4 0.4 1.9e-14 53.4 0.1 2.1 2 0 0 2 2 2 1 SRR1 TPR_2 PF07719.17 EEQ28945.1 - 3.5e-07 29.8 0.0 0.072 13.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.31 EEQ28945.1 - 2.9e-05 23.9 0.0 8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_1 PF00515.28 EEQ28945.1 - 0.001 18.8 0.0 3.5 7.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ28945.1 - 0.0085 15.8 0.1 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 EEQ28945.1 - 0.015 16.0 0.1 2.4 8.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ28945.1 - 0.041 14.2 0.0 1.1 9.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ28945.1 - 0.056 14.3 0.7 22 6.2 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_5 PF13857.6 EEQ28946.1 - 7.2e-19 67.6 5.8 1.1e-09 38.3 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ28946.1 - 4.8e-13 49.3 0.0 5.2e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ28946.1 - 8.9e-13 48.6 0.1 1.7e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EEQ28946.1 - 8.8e-09 35.4 1.1 0.0049 17.3 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EEQ28946.1 - 3e-07 30.2 0.3 0.43 11.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat RILP PF11461.8 EEQ28946.1 - 0.018 15.3 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein bZIP_1 PF00170.21 EEQ28946.1 - 0.052 13.6 7.1 0.11 12.6 7.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor AMP-binding PF00501.28 EEQ28947.1 - 8.5e-76 255.2 0.0 1.1e-75 254.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EEQ28947.1 - 4.1e-25 88.4 0.0 6.6e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EEQ28947.1 - 9.2e-13 48.3 0.2 4.5e-11 42.9 0.1 3.4 3 0 0 3 3 3 1 Phosphopantetheine attachment site DegT_DnrJ_EryC1 PF01041.17 EEQ28948.1 - 3.9e-51 174.5 0.0 9.4e-51 173.2 0.0 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.22 EEQ28948.1 - 1.1e-17 65.0 0.0 2.6e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EEQ28948.1 - 0.00035 20.5 0.0 0.00089 19.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ADP_PFK_GK PF04587.15 EEQ28948.1 - 0.02 13.5 0.0 0.039 12.5 0.0 1.4 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Semialdhyde_dh PF01118.24 EEQ28948.1 - 0.035 14.5 0.0 0.081 13.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pro_isomerase PF00160.21 EEQ28949.1 - 0.14 12.4 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 5_nucleotid_C PF02872.18 EEQ28952.1 - 2.1e-36 125.5 0.0 3.9e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EEQ28952.1 - 0.007 16.9 0.0 0.013 16.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA-synt_1e PF01406.19 EEQ28953.1 - 8.6e-114 379.9 0.0 1.4e-113 379.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EEQ28953.1 - 9.7e-06 24.6 0.2 0.069 11.9 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EEQ28953.1 - 0.00038 20.9 0.0 0.0014 19.1 0.0 2.0 1 0 0 1 1 1 1 DALR domain GCD14 PF08704.10 EEQ28954.1 - 7.9e-64 215.7 0.0 5.5e-63 212.9 0.0 2.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EEQ28954.1 - 0.037 13.8 0.7 0.077 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MetOD2 PF18548.1 EEQ28954.1 - 0.087 12.9 1.5 0.61 10.2 0.2 2.5 2 0 0 2 2 2 0 Metanogen output domain 2 ABC_membrane PF00664.23 EEQ28955.1 - 4.6e-85 285.6 38.7 1.1e-44 153.1 14.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ28955.1 - 6.3e-70 234.0 0.0 1.8e-34 119.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ28955.1 - 2e-15 56.8 0.1 8.3e-05 22.1 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ28955.1 - 1.1e-07 31.5 2.2 0.012 15.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DEAD PF00270.29 EEQ28955.1 - 2.4e-07 30.7 0.1 0.00041 20.2 0.0 2.8 3 0 0 3 3 2 2 DEAD/DEAH box helicase ABC_ATPase PF09818.9 EEQ28955.1 - 3.8e-07 29.3 0.4 0.015 14.1 0.1 2.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EEQ28955.1 - 6.2e-07 30.0 1.0 0.0079 16.6 0.1 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EEQ28955.1 - 6.9e-07 29.6 0.2 0.013 15.8 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EEQ28955.1 - 9.4e-06 25.6 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ28955.1 - 1.1e-05 25.3 0.1 0.04 13.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EEQ28955.1 - 1.8e-05 25.3 0.7 0.15 12.6 0.1 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EEQ28955.1 - 6.4e-05 23.1 2.3 0.21 11.9 0.3 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 EEQ28955.1 - 0.00035 20.6 0.0 1.2 9.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 EEQ28955.1 - 0.00038 20.9 0.1 2.1 8.8 0.0 4.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EEQ28955.1 - 0.0014 18.8 0.5 1.2 9.1 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain Zeta_toxin PF06414.12 EEQ28955.1 - 0.0029 16.9 0.0 0.2 10.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 EEQ28955.1 - 0.0056 16.2 0.2 1.1 8.7 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EEQ28955.1 - 0.0066 15.8 0.1 0.43 9.9 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.6 EEQ28955.1 - 0.018 14.7 0.2 12 5.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 EEQ28955.1 - 0.019 15.1 0.0 8.6 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EEQ28955.1 - 0.025 14.6 0.0 35 4.4 0.0 4.0 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 EEQ28955.1 - 0.026 13.7 0.0 0.58 9.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_25 PF13481.6 EEQ28955.1 - 0.035 13.7 2.9 5.5 6.5 0.0 3.9 5 0 0 5 5 5 0 AAA domain AAA_10 PF12846.7 EEQ28955.1 - 0.041 12.8 0.0 8.7 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain IF3_C PF00707.22 EEQ28955.1 - 0.055 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain AAA_21 PF13304.6 EEQ28955.1 - 0.14 11.9 5.0 1.1 9.0 0.1 3.1 3 1 1 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EEQ28955.1 - 0.14 12.7 0.0 22 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EEQ28955.1 - 0.6 10.2 4.0 23 5.0 0.1 3.6 5 0 0 5 5 3 0 Dynamin family ATP-synt_ab PF00006.25 EEQ28955.1 - 1.6 8.3 7.7 28 4.3 6.7 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF1688 PF07958.11 EEQ28956.1 - 1.6e-163 544.4 0.0 1.9e-163 544.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) LRR_4 PF12799.7 EEQ28957.1 - 0.051 14.0 3.8 11 6.5 0.8 4.4 3 1 1 5 5 5 0 Leucine Rich repeats (2 copies) TrkH PF02386.16 EEQ28959.1 - 5.5e-149 496.8 1.1 1.4e-146 488.9 0.6 2.0 2 0 0 2 2 2 2 Cation transport protein COesterase PF00135.28 EEQ28962.1 - 3.1e-91 306.8 0.2 6.5e-82 276.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EEQ28962.1 - 1.7e-12 47.6 0.0 3.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EEQ28962.1 - 0.019 13.9 0.1 0.064 12.1 0.1 1.7 1 1 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 EEQ28962.1 - 0.039 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Dynamin_M PF01031.20 EEQ28963.1 - 1.2e-101 339.7 0.0 2.2e-101 338.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EEQ28963.1 - 3.1e-46 157.5 0.3 7.5e-46 156.2 0.3 1.7 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 EEQ28963.1 - 1.5e-28 98.7 2.5 4.3e-28 97.3 2.5 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EEQ28963.1 - 0.0019 18.2 2.1 0.034 14.2 2.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 EEQ28964.1 - 8.4e-109 362.2 0.0 1.2e-108 361.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EEQ28964.1 - 2.3e-44 150.1 0.0 5e-44 149.0 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EEQ28964.1 - 4.9e-15 55.8 2.3 1e-14 54.7 2.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HSBP1 PF06825.12 EEQ28964.1 - 0.11 12.4 0.1 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 WD40 PF00400.32 EEQ28965.1 - 5.8e-26 90.3 3.1 0.00014 22.6 0.0 8.0 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ28965.1 - 3.7e-15 56.0 0.3 0.0024 18.1 0.0 5.4 3 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ28965.1 - 5.4e-06 25.6 0.1 0.026 13.5 0.0 3.3 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EEQ28965.1 - 0.00029 20.8 0.1 0.055 13.4 0.1 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EEQ28965.1 - 0.00061 19.7 0.1 18 5.4 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EEQ28965.1 - 0.0093 14.7 0.1 0.033 12.9 0.1 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Blt1 PF12754.7 EEQ28965.1 - 0.24 11.7 1.1 0.47 10.8 0.0 2.0 3 0 0 3 3 3 0 Blt1 N-terminal domain DEAD PF00270.29 EEQ28966.1 - 1.3e-41 142.3 0.1 2.3e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ28966.1 - 1.6e-33 115.4 0.1 6.5e-33 113.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EEQ28966.1 - 0.00068 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EEQ28966.1 - 0.00085 19.4 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEQ28966.1 - 0.0028 18.0 0.1 0.027 14.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 EEQ28966.1 - 0.037 14.0 0.3 0.14 12.1 0.1 2.2 1 1 1 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 EEQ28966.1 - 0.05 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase TniB PF05621.11 EEQ28966.1 - 0.059 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EEQ28966.1 - 0.22 11.8 1.0 1.2 9.4 1.0 2.1 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.8 EEQ28967.1 - 5.4e-72 241.5 0.5 1.2e-71 240.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EEQ28967.1 - 2.6e-23 82.3 2.5 2.7e-23 82.3 0.8 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EEQ28967.1 - 6.3e-12 45.1 0.2 1.2e-11 44.2 0.2 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 EEQ28967.1 - 1.4e-09 38.0 1.4 6.3e-08 32.8 0.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEQ28967.1 - 1.6e-08 34.6 0.6 1.6e-08 34.6 0.6 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EEQ28967.1 - 0.001 19.3 0.2 0.022 15.1 0.0 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EEQ28967.1 - 0.0029 18.3 1.2 0.32 12.0 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-LYAR PF08790.11 EEQ28967.1 - 0.17 11.8 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-ISL3 PF14690.6 EEQ28967.1 - 0.2 12.3 1.3 4.4 8.0 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PRP9_N PF16958.5 EEQ28967.1 - 0.21 11.6 12.9 0.69 9.9 0.5 3.3 3 1 1 4 4 4 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2 PF00096.26 EEQ28967.1 - 0.41 11.2 4.3 0.91 10.1 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_ligase_A_M PF01068.21 EEQ28969.1 - 1.1e-20 74.1 0.0 1.8e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EEQ28969.1 - 6e-18 65.8 0.0 1.2e-17 64.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EEQ28969.1 - 3.4e-05 24.2 0.0 0.00012 22.5 0.0 1.8 2 0 0 2 2 2 1 RNA ligase LRR_RI_capping PF18779.1 EEQ28969.1 - 0.33 10.7 2.0 1.6 8.5 0.1 2.6 2 0 0 2 2 2 0 Capping Ribonuclease inhibitor Leucine Rich Repeat ANAPC8 PF04049.13 EEQ28970.1 - 2.3e-51 173.5 0.0 6.8e-51 172.0 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EEQ28970.1 - 8.5e-25 85.5 6.0 0.00017 21.2 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ28970.1 - 8.5e-21 72.4 16.6 1.7e-05 24.7 0.0 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ28970.1 - 6.5e-20 69.6 18.7 0.058 13.5 2.8 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ28970.1 - 6.7e-14 52.2 1.8 0.1 13.1 0.2 6.8 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ28970.1 - 1.1e-11 44.1 3.2 1e-06 28.3 0.3 4.7 2 2 2 4 4 4 2 TPR repeat TPR_14 PF13428.6 EEQ28970.1 - 3.2e-11 43.1 15.6 0.0067 17.2 0.0 8.2 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ28970.1 - 5.9e-11 42.8 10.5 1.6e-05 25.4 0.0 6.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ28970.1 - 1.4e-10 41.3 6.2 0.089 13.1 0.0 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ28970.1 - 5.7e-10 39.3 15.5 0.1 12.8 0.3 6.5 6 0 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EEQ28970.1 - 1.6e-07 31.3 10.3 0.00037 20.6 0.5 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ28970.1 - 3.1e-07 30.3 4.2 2.4 8.7 0.0 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 EEQ28970.1 - 9.8e-05 21.7 8.2 0.0024 17.1 4.2 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ28970.1 - 0.0002 21.8 20.4 13 6.7 0.1 9.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ28970.1 - 0.00088 19.1 10.7 2.8 8.2 0.0 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat DUF3808 PF10300.9 EEQ28970.1 - 0.043 12.6 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) HrpB1_HrpK PF09613.10 EEQ28970.1 - 0.05 13.2 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Sel1 PF08238.12 EEQ28970.1 - 0.054 14.2 6.2 13 6.6 0.1 4.1 3 0 0 3 3 3 0 Sel1 repeat TPR_3 PF07720.12 EEQ28970.1 - 0.38 10.8 4.1 0.48 10.5 0.1 3.2 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ28970.1 - 0.6 9.4 3.5 0.87 8.9 0.2 2.8 4 0 0 4 4 4 0 MalT-like TPR region TPR_10 PF13374.6 EEQ28970.1 - 2.3 8.2 10.9 86 3.2 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat polyprenyl_synt PF00348.17 EEQ28971.1 - 7.6e-90 300.4 0.0 9.6e-90 300.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase LIX1 PF14954.6 EEQ28971.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Limb expression 1 Glycogen_syn PF05693.13 EEQ28972.1 - 0 1019.0 0.0 0 1018.3 0.0 1.2 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 EEQ28972.1 - 9e-06 25.8 0.2 3.1e-05 24.0 0.2 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EEQ28972.1 - 2.7e-05 23.8 0.0 0.0074 15.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEQ28972.1 - 5.2e-05 23.7 0.0 0.04 14.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EEQ28972.1 - 7.3e-05 23.3 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EEQ28972.1 - 0.00014 21.7 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain NPCC PF08058.11 EEQ28973.1 - 6e-24 84.6 0.0 9.3e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component AMP-binding PF00501.28 EEQ28974.1 - 7.6e-16 57.7 0.0 6.8e-15 54.6 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Ribosomal_L19 PF01245.20 EEQ28976.1 - 9.1e-12 44.9 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L19 Methyltransf_24 PF13578.6 EEQ28977.1 - 1.1e-12 48.9 0.0 1.8e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EEQ28977.1 - 2e-05 23.8 0.0 0.0001 21.6 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase Hap4_Hap_bind PF10297.9 EEQ28978.1 - 3.3e-08 33.4 7.7 7.2e-08 32.3 7.7 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EEQ28978.1 - 4.3e-07 29.9 10.8 4.3e-07 29.9 10.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor dsrm PF00035.26 EEQ28978.1 - 0.091 13.5 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif bZIP_2 PF07716.15 EEQ28978.1 - 0.32 11.1 18.3 0.11 12.7 12.9 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DUF737 PF05300.11 EEQ28978.1 - 1.4 9.3 12.6 0.29 11.5 6.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Cauli_AT PF03233.13 EEQ28978.1 - 1.5 8.8 5.7 10 6.0 5.4 2.1 1 1 1 2 2 2 0 Aphid transmission protein Mito_carr PF00153.27 EEQ28979.1 - 1.1e-08 34.9 1.5 0.013 15.4 0.0 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein Fer2 PF00111.27 EEQ28980.1 - 7e-14 51.5 0.6 1e-13 51.0 0.6 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.12 EEQ28981.1 - 2.9e-39 134.5 8.5 2.9e-39 134.5 8.5 2.2 2 1 0 2 2 2 1 Rrp15p RRN3 PF05327.11 EEQ28981.1 - 4.7 5.6 6.6 6 5.3 6.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SRP54 PF00448.22 EEQ28982.1 - 4.1e-74 248.5 2.1 7.8e-74 247.6 2.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EEQ28982.1 - 2.8e-28 98.4 0.1 2.8e-28 98.4 0.1 4.4 2 2 2 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 EEQ28982.1 - 3.7e-20 71.9 0.4 9.2e-20 70.6 0.4 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EEQ28982.1 - 1.1e-06 28.3 0.6 4.7e-06 26.3 0.5 2.1 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EEQ28982.1 - 1.9e-06 28.1 0.5 4.2e-06 27.0 0.1 1.9 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 EEQ28982.1 - 4.8e-05 23.8 2.5 5.1e-05 23.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EEQ28982.1 - 0.0001 21.6 0.1 0.0002 20.7 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 EEQ28982.1 - 0.00021 20.4 1.0 0.0033 16.4 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EEQ28982.1 - 0.00024 21.5 0.1 0.0007 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 EEQ28982.1 - 0.00065 19.6 0.8 0.024 14.4 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 EEQ28982.1 - 0.0019 17.5 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase APS_kinase PF01583.20 EEQ28982.1 - 0.0023 17.8 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ResIII PF04851.15 EEQ28982.1 - 0.003 17.6 1.2 0.027 14.5 1.3 2.2 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EEQ28982.1 - 0.0049 16.6 0.3 0.0049 16.6 0.3 2.0 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EEQ28982.1 - 0.0072 16.4 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 EEQ28982.1 - 0.01 16.1 0.0 0.039 14.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EEQ28982.1 - 0.011 15.2 1.9 2.2 7.7 0.1 3.2 2 1 0 3 3 3 0 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.17 EEQ28982.1 - 0.011 15.4 0.4 0.038 13.7 0.2 2.0 2 0 0 2 2 1 0 Thymidylate kinase AAA_18 PF13238.6 EEQ28982.1 - 0.014 15.9 0.1 0.043 14.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 EEQ28982.1 - 0.017 15.2 0.1 0.08 13.0 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Methyltransf_25 PF13649.6 EEQ28982.1 - 0.026 15.2 0.3 2.3 9.0 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain AAA_19 PF13245.6 EEQ28982.1 - 0.039 14.3 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EEQ28982.1 - 0.04 14.1 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EEQ28982.1 - 0.043 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EEQ28982.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family MobB PF03205.14 EEQ28982.1 - 0.051 13.5 0.2 0.16 11.9 0.1 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 EEQ28982.1 - 0.074 13.0 0.9 0.67 9.9 0.2 2.4 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EEQ28982.1 - 0.075 13.6 0.1 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter VirE PF05272.11 EEQ28982.1 - 0.11 12.2 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Virulence-associated protein E AAA_14 PF13173.6 EEQ28982.1 - 0.17 12.0 0.0 0.51 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain HAUS2 PF15003.6 EEQ28982.1 - 0.2 11.4 0.1 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 PhoD PF09423.10 EEQ28983.1 - 1.7e-39 135.8 0.0 5.3e-39 134.2 0.0 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 EEQ28983.1 - 0.013 16.0 0.8 0.092 13.3 0.8 2.3 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EEQ28983.1 - 0.06 13.9 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Glyco_hydro_18 PF00704.28 EEQ28984.1 - 2.4e-16 60.3 0.0 2.8e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF496 PF04363.12 EEQ28984.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF496) adh_short_C2 PF13561.6 EEQ28988.1 - 6.1e-58 196.1 0.1 7.6e-58 195.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ28988.1 - 4.7e-47 160.0 0.1 6.7e-47 159.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ28988.1 - 8.2e-13 48.6 0.6 1.1e-12 48.3 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ28988.1 - 0.0011 18.5 0.2 0.0024 17.4 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glu_dehyd_C PF16912.5 EEQ28988.1 - 0.035 13.6 0.0 0.075 12.5 0.0 1.6 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus HATPase_c PF02518.26 EEQ28988.1 - 0.057 13.9 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GDP_Man_Dehyd PF16363.5 EEQ28988.1 - 0.071 12.5 0.1 0.092 12.1 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EEQ28988.1 - 0.086 11.8 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TRAPPC10 PF12584.8 EEQ28989.1 - 0.078 12.7 0.5 0.28 10.9 0.5 1.9 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 Macoilin PF09726.9 EEQ28989.1 - 0.1 11.2 71.9 0.11 11.0 31.1 2.2 2 0 0 2 2 2 0 Macoilin family PKcGMP_CC PF16808.5 EEQ28989.1 - 1 9.3 8.7 2.5 8.0 4.5 3.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CoA_transf_3 PF02515.17 EEQ28990.1 - 1.7e-62 211.7 0.0 2.2e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III SelP_N PF04592.14 EEQ28991.1 - 0.96 8.8 9.4 2.7 7.3 9.4 1.8 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Methyltransf_23 PF13489.6 EEQ28992.1 - 3e-13 50.0 0.0 1.2e-12 48.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ28992.1 - 8.1e-05 23.3 0.2 0.0021 18.7 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ28992.1 - 0.0013 19.3 0.0 0.0023 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ28992.1 - 0.0055 17.4 0.0 0.012 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ28992.1 - 0.008 16.0 0.0 0.043 13.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CAF1A PF12253.8 EEQ28994.1 - 8.6e-22 77.1 4.4 8.6e-22 77.1 4.4 3.6 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 EEQ28994.1 - 0.014 15.1 61.0 0.026 14.2 61.0 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.12 EEQ28994.1 - 0.2 11.5 31.3 0.066 13.0 28.2 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CNDH2_C PF16858.5 EEQ28994.1 - 0.56 10.0 33.6 1.9 8.3 22.6 3.0 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Mem_trans PF03547.18 EEQ28994.1 - 1.3 7.3 2.8 1.8 6.8 2.8 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF262 PF03235.14 EEQ28994.1 - 1.4 9.1 10.2 3 7.9 10.2 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF2052 PF09747.9 EEQ28994.1 - 2.4 8.2 36.1 6.5 6.8 31.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4407 PF14362.6 EEQ28994.1 - 8.9 5.6 13.7 14 4.9 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Caudo_TAP PF02413.17 EEQ28997.1 - 0.053 13.7 0.3 0.16 12.2 0.3 1.8 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK IPP-2 PF04979.14 EEQ28998.1 - 1.1e-21 78.0 10.8 1.1e-21 78.0 10.8 2.2 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) CRAL_TRIO PF00650.20 EEQ28999.1 - 1.6e-12 47.4 0.0 2.4e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ28999.1 - 4.1e-09 36.5 0.0 1.1e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TAF6_C PF07571.13 EEQ29000.1 - 5.8e-30 103.5 0.0 1.3e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EEQ29000.1 - 3.9e-25 87.8 0.2 1.5e-24 85.9 0.0 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 EEQ29000.1 - 0.0018 18.3 0.1 0.0051 16.9 0.1 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EEQ29000.1 - 0.0064 16.8 0.0 0.018 15.4 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EEQ29000.1 - 0.0076 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 EEQ29000.1 - 0.086 13.1 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAM_decarbox PF01536.16 EEQ29002.1 - 1.7e-130 435.1 0.0 2.1e-130 434.9 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TAFII28 PF04719.14 EEQ29003.1 - 3.9e-28 97.4 0.9 1.1e-25 89.6 0.3 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region Ribosomal_60s PF00428.19 EEQ29003.1 - 0.017 15.7 2.3 0.017 15.7 2.3 3.0 2 1 0 2 2 2 0 60s Acidic ribosomal protein Tim54 PF11711.8 EEQ29003.1 - 0.18 10.6 2.6 0.26 10.0 2.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 60KD_IMP PF02096.20 EEQ29004.1 - 2.9e-16 59.8 0.0 5.4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.11 EEQ29005.1 - 7e-35 118.9 0.0 8.6e-35 118.6 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.13 EEQ29006.1 - 1.3e-22 80.1 0.1 2.6e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EEQ29006.1 - 4e-14 52.6 0.0 6.3e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EEQ29006.1 - 5.4e-14 51.7 0.0 9e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EEQ29006.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 TAP C-terminal domain NUP50 PF08911.11 EEQ29006.1 - 0.19 12.4 3.4 1.2 9.9 0.2 3.2 3 0 0 3 3 3 0 NUP50 (Nucleoporin 50 kDa) ParA PF10609.9 EEQ29007.1 - 2e-86 289.5 0.0 1e-60 205.2 0.0 2.0 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EEQ29007.1 - 3.3e-10 40.1 0.0 1.3e-09 38.2 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EEQ29007.1 - 1.3e-06 27.9 0.0 1.3e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 EEQ29007.1 - 3.5e-06 27.1 0.7 2.5e-05 24.3 0.7 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EEQ29007.1 - 4.2e-05 22.9 0.3 0.0004 19.7 0.6 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 EEQ29007.1 - 0.00055 19.6 0.1 0.0009 18.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 EEQ29007.1 - 0.0043 16.6 0.2 0.032 13.7 0.2 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 EEQ29007.1 - 0.0071 15.4 0.2 0.012 14.6 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 EEQ29007.1 - 0.011 15.6 0.5 0.75 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EEQ29007.1 - 0.027 14.4 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase OrfB_Zn_ribbon PF07282.11 EEQ29007.1 - 0.14 12.1 0.2 0.35 10.8 0.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain CLP1_P PF16575.5 EEQ29007.1 - 0.18 11.6 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 EEQ29007.1 - 0.22 11.4 0.8 0.45 10.4 0.8 1.4 1 0 0 1 1 1 0 RsgA GTPase Desulfoferrod_N PF06397.12 EEQ29007.1 - 1.1 9.0 5.3 0.16 11.6 0.8 1.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain COG2 PF06148.11 EEQ29009.1 - 8.6e-33 113.3 1.6 1.6e-32 112.4 1.6 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EEQ29009.1 - 1.5e-06 28.2 1.0 3.6e-06 26.9 0.1 2.1 1 1 1 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 EEQ29009.1 - 0.0033 16.2 2.8 0.0048 15.6 2.8 1.2 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 EEQ29009.1 - 0.012 14.9 0.4 0.029 13.6 0.1 1.6 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 EEQ29009.1 - 0.014 15.6 0.8 0.014 15.6 0.8 2.1 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 EEQ29009.1 - 0.021 14.7 1.4 0.084 12.8 1.4 2.0 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain KxDL PF10241.9 EEQ29009.1 - 0.03 14.6 0.4 0.17 12.2 0.2 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein Atg14 PF10186.9 EEQ29009.1 - 0.034 13.2 1.7 0.045 12.8 0.9 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EEQ29009.1 - 0.04 12.8 4.0 0.06 12.2 4.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2120 PF09893.9 EEQ29009.1 - 0.053 13.6 0.2 0.1 12.7 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) IFT20 PF14931.6 EEQ29009.1 - 0.076 13.2 2.5 0.21 11.8 2.5 1.7 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 FTCD_C PF04961.12 EEQ29009.1 - 0.12 12.1 0.3 0.56 9.9 0.0 1.9 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase UPF0242 PF06785.11 EEQ29009.1 - 0.25 11.4 6.5 0.58 10.2 6.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EEQ29009.1 - 0.32 11.1 1.2 1.4 9.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Drc1-Sld2 PF11719.8 EEQ29009.1 - 0.36 10.3 2.3 0.5 9.9 2.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein IFT57 PF10498.9 EEQ29009.1 - 1.2 8.0 7.0 0.088 11.8 0.9 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF3295 PF11702.8 EEQ29009.1 - 3.3 6.9 6.3 5.8 6.1 6.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3295) PLC-beta_C PF08703.10 EEQ29009.1 - 3.8 7.5 8.5 1.8 8.5 5.0 2.1 2 1 0 2 2 2 0 PLC-beta C terminal Nop25 PF09805.9 EEQ29009.1 - 5.8 7.4 8.9 1.9 9.0 5.0 1.9 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) Ribosomal_L1 PF00687.21 EEQ29010.1 - 1.5e-33 116.3 0.0 2.5e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family APH PF01636.23 EEQ29011.1 - 0.062 13.2 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 EEQ29012.1 - 3.2e-32 111.8 44.0 6.6e-32 110.8 44.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ29012.1 - 1.3e-09 37.0 19.3 2.6e-09 36.1 19.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_16 PF00722.21 EEQ29013.1 - 2.3e-05 23.9 0.3 6.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 FAD_binding_3 PF01494.19 EEQ29014.1 - 3.2e-61 207.5 0.0 2.4e-60 204.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EEQ29014.1 - 1.1e-26 93.8 0.0 2.9e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EEQ29014.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NMT1 PF09084.11 EEQ29015.1 - 0.01 15.8 0.0 0.21 11.5 0.0 2.2 1 1 0 2 2 2 0 NMT1/THI5 like NMT1_3 PF16868.5 EEQ29015.1 - 0.034 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family SBP_bac_3 PF00497.20 EEQ29015.1 - 0.097 12.1 0.0 5.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 p450 PF00067.22 EEQ29016.1 - 1.8e-57 195.1 0.0 2.5e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PQ-loop PF04193.14 EEQ29018.1 - 1.9e-21 75.6 5.1 3.4e-14 52.3 0.7 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EEQ29018.1 - 1.3e-05 26.1 0.9 2.2e-05 25.3 0.9 1.4 1 1 0 1 1 1 1 ER lumen protein retaining receptor Glyco_hydro_31 PF01055.26 EEQ29019.1 - 3.5e-137 458.2 8.6 5.1e-137 457.7 8.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EEQ29019.1 - 4.9e-26 90.8 1.2 1.2e-25 89.6 0.2 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EEQ29019.1 - 2.7e-08 33.9 0.2 7.9e-08 32.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NDK PF00334.19 EEQ29020.1 - 1.2e-54 183.9 0.0 1.4e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.9 EEQ29021.1 - 1.8e-29 102.0 0.0 3.2e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EEQ29021.1 - 0.0022 18.5 0.4 0.0041 17.6 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) MTHFR PF02219.17 EEQ29022.1 - 4.3e-101 338.0 0.0 6.4e-101 337.4 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MFS_1 PF07690.16 EEQ29023.1 - 1.9e-29 102.7 26.7 1.9e-29 102.7 26.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Oxidored_q5_N PF01059.17 EEQ29023.1 - 0.055 13.5 1.0 0.14 12.3 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus TGT PF01702.18 EEQ29024.1 - 1.9e-64 218.0 0.0 2.4e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.17 EEQ29025.1 - 2e-43 148.3 0.0 2.3e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EEQ29025.1 - 0.011 15.1 0.0 0.026 14.0 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 EEQ29025.1 - 0.031 14.5 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEQ29025.1 - 0.06 13.4 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EEQ29025.1 - 0.066 12.2 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GIY-YIG PF01541.24 EEQ29026.1 - 2.6e-09 37.2 0.0 6.1e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 EEQ29026.1 - 8.5e-05 22.7 5.6 0.00016 21.8 5.6 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.29 EEQ29026.1 - 0.069 13.0 7.8 0.13 12.2 7.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 EEQ29026.1 - 0.11 12.8 2.9 0.2 11.9 2.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 EEQ29026.1 - 0.13 12.2 9.5 0.12 12.3 5.7 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PLU-1 PF08429.11 EEQ29027.1 - 2.4e-108 362.3 17.8 4.9e-106 354.7 15.8 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EEQ29027.1 - 8e-43 145.5 0.4 2.3e-42 144.0 0.4 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EEQ29027.1 - 8.8e-22 77.6 0.1 2.6e-21 76.1 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EEQ29027.1 - 1.7e-18 66.3 3.2 3.8e-18 65.1 3.2 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 EEQ29027.1 - 2.7e-18 65.6 27.4 4.7e-10 39.2 6.5 3.6 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 EEQ29027.1 - 2.5e-10 40.6 9.4 7e-10 39.1 9.4 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 EEQ29027.1 - 0.012 15.2 11.8 0.019 14.6 2.2 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 EEQ29027.1 - 0.22 11.6 20.9 0.3 11.2 5.1 3.0 2 0 0 2 2 2 0 PHD-finger tRNA-synt_His PF13393.6 EEQ29027.1 - 0.27 10.5 1.8 0.71 9.1 1.8 1.7 1 0 0 1 1 1 0 Histidyl-tRNA synthetase PHD_2 PF13831.6 EEQ29027.1 - 2.2 7.9 12.9 0.014 14.9 1.5 2.7 2 0 0 2 2 2 0 PHD-finger DUF4219 PF13961.6 EEQ29028.1 - 0.0011 18.6 0.3 0.0016 18.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Pox_F17 PF04767.12 EEQ29028.1 - 0.096 13.2 4.5 1.2 9.6 0.2 2.1 1 1 1 2 2 2 0 DNA-binding 11 kDa phosphoprotein DHHA2 PF02833.14 EEQ29029.1 - 4.3e-21 75.6 0.0 8e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EEQ29029.1 - 3.5e-06 27.2 0.0 1.1e-05 25.6 0.0 1.9 1 1 0 1 1 1 1 DHH family ARA70 PF12489.8 EEQ29029.1 - 0.09 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear coactivator KRTDAP PF15200.6 EEQ29029.1 - 0.11 12.3 0.1 0.34 10.7 0.1 1.8 1 0 0 1 1 1 0 Keratinocyte differentiation-associated Transglut_core PF01841.19 EEQ29030.1 - 3.8e-11 43.4 0.2 1.8e-10 41.3 0.2 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.17 EEQ29030.1 - 4.1e-08 32.8 0.1 8.9e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEQ29030.1 - 1.4e-05 24.6 2.2 1.9e-05 24.2 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEQ29030.1 - 0.002 18.0 0.1 0.02 14.7 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain Transglut_core2 PF13369.6 EEQ29030.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Transglutaminase-like superfamily MIP PF00230.20 EEQ29031.1 - 2.7e-47 161.4 14.4 3.4e-47 161.0 14.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein HDA2-3 PF11496.8 EEQ29032.1 - 2.6e-33 115.5 2.9 2.1e-17 63.2 0.0 2.8 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 PRKG1_interact PF15898.5 EEQ29032.1 - 0.28 12.1 29.4 0.91 10.5 6.2 3.6 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Tropomyosin_1 PF12718.7 EEQ29032.1 - 1.5 9.0 33.4 0.21 11.8 20.6 3.3 1 1 2 3 3 3 0 Tropomyosin like ADIP PF11559.8 EEQ29032.1 - 2.4 8.2 33.7 1.9 8.6 7.9 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 EEQ29032.1 - 2.5 8.1 17.9 0.28 11.2 8.2 2.9 2 0 0 2 2 2 0 Laminin Domain II CENP-F_leu_zip PF10473.9 EEQ29032.1 - 2.5 8.1 40.7 0.77 9.8 16.1 3.6 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lectin_N PF03954.14 EEQ29032.1 - 9.1 6.0 8.8 19 5.0 1.0 3.8 3 1 1 4 4 4 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 EEQ29032.1 - 9.3 6.3 16.0 0.73 9.9 2.5 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) FMO-like PF00743.19 EEQ29033.1 - 5.2e-40 137.4 0.0 5.3e-19 68.0 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EEQ29033.1 - 6.5e-11 42.0 0.0 6.5e-10 38.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ29033.1 - 7.7e-11 41.8 0.0 1.1e-06 28.2 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ29033.1 - 4.2e-07 30.1 0.1 1.5e-06 28.4 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EEQ29033.1 - 1.5e-05 24.3 0.0 0.00075 18.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EEQ29033.1 - 5e-05 23.3 0.0 0.00054 20.0 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EEQ29033.1 - 6.9e-05 22.2 0.1 0.0039 16.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EEQ29033.1 - 0.011 15.4 0.2 0.12 11.9 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EEQ29033.1 - 0.052 14.1 0.1 1 10.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEQ29033.1 - 0.072 11.8 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein MCRA PF06100.11 EEQ29033.1 - 0.17 10.6 0.1 0.37 9.5 0.0 1.4 2 0 0 2 2 2 0 MCRA family Glu_dehyd_C PF16912.5 EEQ29033.1 - 0.23 10.9 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus POT1 PF02765.17 EEQ29034.1 - 4.4e-18 65.5 0.0 7.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 EEQ29034.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Replication protein A OB domain Aminotran_1_2 PF00155.21 EEQ29036.1 - 3.9e-26 92.1 0.0 4.9e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 EEQ29036.1 - 0.0007 18.4 0.0 0.035 12.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III IF4E PF01652.18 EEQ29037.1 - 1.3e-54 184.3 0.0 2.2e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.19 EEQ29038.1 - 1.5e-27 96.8 0.5 1.7e-13 51.0 0.4 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain SPC22 PF04573.12 EEQ29039.1 - 5.6e-38 130.1 0.7 2.9e-35 121.3 0.7 2.2 1 1 0 1 1 1 1 Signal peptidase subunit Pmp3 PF01679.17 EEQ29040.1 - 9.7e-21 73.7 9.8 1.4e-20 73.2 9.8 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BCDHK_Adom3 PF10436.9 EEQ29042.1 - 9e-45 152.4 0.3 1.7e-44 151.5 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EEQ29042.1 - 2.6e-06 27.9 0.0 1.1e-05 25.9 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EEQ29042.1 - 0.12 12.3 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EEQ29042.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.8 EEQ29043.1 - 5.6e-86 287.8 0.0 3e-84 282.1 0.0 2.4 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EEQ29043.1 - 2.3e-71 239.8 0.8 1.9e-70 236.8 0.5 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EEQ29043.1 - 1.2e-44 152.8 0.1 2e-44 152.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ29043.1 - 1.1e-19 71.2 0.0 2.4e-19 70.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rad60-SLD PF11976.8 EEQ29043.1 - 0.035 13.9 0.5 4.7 7.1 0.0 3.8 5 0 0 5 5 5 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EEQ29043.1 - 0.089 12.6 0.1 42 4.0 0.0 4.0 4 0 0 4 4 4 0 Ubiquitin family EMP24_GP25L PF01105.24 EEQ29044.1 - 3.1e-46 157.6 0.1 3.6e-46 157.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IrmA PF18673.1 EEQ29044.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 interleukin receptor mimic protein A CTD_bind PF04818.13 EEQ29045.1 - 2.3e-10 41.2 0.0 5.2e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4748 PF15932.5 EEQ29047.1 - 6.2e-13 48.3 0.3 6.2e-13 48.3 0.3 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4748) Toprim_Crpt PF13342.6 EEQ29047.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase ERCC3_RAD25_C PF16203.5 EEQ29048.1 - 1.5e-122 407.6 0.7 2.6e-122 406.8 0.7 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EEQ29048.1 - 4.8e-34 117.3 0.0 2e-33 115.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ29048.1 - 1.2e-15 57.9 0.0 2.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ29048.1 - 7.2e-14 52.1 0.1 1.7e-13 50.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EEQ29048.1 - 2.6e-08 33.0 0.0 3.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EEQ29048.1 - 0.00031 20.5 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 EEQ29048.1 - 0.00076 18.5 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4677 PF15726.5 EEQ29048.1 - 0.0043 17.3 0.8 0.0088 16.2 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4677) SH3BGR PF04908.15 EEQ29048.1 - 0.057 13.6 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Dynamin_N PF00350.23 EEQ29049.1 - 2.2e-21 76.6 0.0 5.2e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EEQ29049.1 - 4.4e-12 45.8 0.0 1.9e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EEQ29049.1 - 0.00013 22.0 0.0 0.00077 19.5 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ29049.1 - 0.00024 20.7 0.2 0.04 13.4 0.1 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_15 PF13175.6 EEQ29049.1 - 0.025 14.3 0.1 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain SURF6 PF04935.12 EEQ29050.1 - 0.25 11.1 6.6 0.45 10.3 6.6 1.5 1 0 0 1 1 1 0 Surfeit locus protein 6 NUDIX PF00293.28 EEQ29051.1 - 1.2e-17 64.2 0.2 2e-17 63.5 0.2 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EEQ29051.1 - 1.7e-14 54.3 0.0 9.8e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EEQ29051.1 - 8.2e-06 25.4 0.5 1.4e-05 24.6 0.5 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain HTH_ParB PF17762.1 EEQ29051.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 HTH domain found in ParB protein Pkinase PF00069.25 EEQ29052.1 - 3.7e-70 236.3 0.0 5.2e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29052.1 - 8.7e-33 113.7 0.0 1.5e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ29052.1 - 0.0005 19.5 0.6 0.0012 18.3 0.6 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ29052.1 - 0.0014 18.0 0.2 0.0058 16.0 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EEQ29052.1 - 0.03 13.1 0.1 0.03 13.1 0.1 2.3 3 0 0 3 3 3 0 Fungal protein kinase Haspin_kinase PF12330.8 EEQ29052.1 - 0.046 12.7 0.2 0.22 10.5 0.1 1.9 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 EEQ29052.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Questin_oxidase PF14027.6 EEQ29053.1 - 4.3e-91 306.0 0.4 5.3e-91 305.7 0.4 1.1 1 0 0 1 1 1 1 Questin oxidase-like Lactamase_B_5 PF14597.6 EEQ29053.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily GTP_cyclohydroI PF01227.22 EEQ29055.1 - 7.8e-56 188.3 0.9 9.8e-54 181.5 0.9 2.2 1 1 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EEQ29055.1 - 0.0039 17.3 0.0 0.008 16.3 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Cu_amine_oxidN2 PF02727.16 EEQ29055.1 - 0.089 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain MbeB_N PF04837.12 EEQ29055.1 - 1.3 9.4 4.5 46 4.4 0.1 3.1 3 0 0 3 3 3 0 MbeB-like, N-term conserved region CAF1C_H4-bd PF12265.8 EEQ29056.1 - 3.5e-29 100.9 1.0 2.2e-28 98.3 0.8 2.5 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EEQ29056.1 - 1.1e-27 95.7 8.6 3e-05 24.7 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29056.1 - 2.9e-06 27.5 0.7 0.1 12.9 0.1 4.3 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ29056.1 - 0.049 12.3 2.0 5 5.7 0.3 3.4 2 1 0 3 3 3 0 Nucleoporin Nup120/160 XRN_M PF17846.1 EEQ29057.1 - 4.9e-99 332.3 3.3 1e-98 331.2 3.3 1.5 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EEQ29057.1 - 3.2e-82 275.6 0.1 6e-82 274.7 0.1 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EEQ29057.1 - 2.7e-74 249.1 0.1 2.7e-74 249.1 0.1 2.2 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EEQ29057.1 - 3.4e-33 113.7 0.0 9.8e-33 112.2 0.0 1.9 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EEQ29057.1 - 1.3e-23 82.9 0.1 3.4e-23 81.5 0.1 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EEQ29057.1 - 1.3e-08 34.7 0.4 3.2e-08 33.6 0.4 1.7 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 RXLR PF16810.5 EEQ29057.1 - 0.099 13.1 2.8 0.2 12.1 2.8 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Cwf_Cwc_15 PF04889.12 EEQ29057.1 - 0.67 9.6 6.3 1.2 8.8 6.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ACT_7 PF13840.6 EEQ29058.1 - 4.9e-23 80.7 0.6 1.5e-15 56.7 0.1 2.8 2 1 0 2 2 2 2 ACT domain WD40 PF00400.32 EEQ29059.1 - 3.2e-19 68.9 19.3 0.0027 18.5 0.0 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29059.1 - 3.8e-10 39.9 0.2 0.088 13.1 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EEQ29059.1 - 1e-05 25.2 1.4 0.033 14.1 0.0 3.9 5 0 0 5 5 5 2 PQQ enzyme repeat VID27 PF08553.10 EEQ29059.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 EEQ29059.1 - 0.082 11.9 1.3 3.9 6.3 0.0 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Septin PF00735.18 EEQ29060.1 - 1.4e-112 375.6 0.3 2.1e-112 375.0 0.3 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EEQ29060.1 - 1.4e-07 31.6 0.0 3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ29060.1 - 5.6e-06 26.0 2.6 0.00017 21.2 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ29060.1 - 7.6e-06 25.9 1.3 5.6e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EEQ29060.1 - 0.0021 18.3 0.6 0.0074 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EEQ29060.1 - 0.0028 17.2 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 EEQ29060.1 - 0.0059 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EEQ29060.1 - 0.006 15.9 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 EEQ29060.1 - 0.0085 15.2 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Casc1_N PF15927.5 EEQ29060.1 - 0.013 15.3 10.5 0.032 13.9 10.5 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_24 PF13479.6 EEQ29060.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEQ29060.1 - 0.023 14.3 0.4 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain FOXP-CC PF16159.5 EEQ29060.1 - 0.027 15.1 2.3 0.041 14.5 0.8 2.1 1 1 1 2 2 1 0 FOXP coiled-coil domain AAA_16 PF13191.6 EEQ29060.1 - 0.031 14.7 1.3 0.084 13.3 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 EEQ29060.1 - 0.037 13.3 0.0 0.046 12.9 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 EEQ29060.1 - 0.042 12.9 0.4 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.22 EEQ29060.1 - 0.043 13.4 0.3 0.12 12.0 0.3 1.8 1 1 0 1 1 1 0 Ras family NACHT PF05729.12 EEQ29060.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EEQ29060.1 - 0.06 13.9 0.1 0.3 11.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 EEQ29060.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EEQ29060.1 - 0.15 11.8 0.4 5.4 6.8 0.4 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EEQ29060.1 - 0.36 10.9 5.4 6.1 6.9 0.0 3.2 2 1 1 3 3 3 0 Dynamin family DegS PF05384.11 EEQ29060.1 - 4.2 6.9 12.4 2 7.9 7.4 2.6 2 1 1 3 3 3 0 Sensor protein DegS WD40 PF00400.32 EEQ29061.1 - 1.7e-37 126.7 32.4 1.2e-08 35.5 1.2 12.7 13 0 0 13 13 13 6 WD domain, G-beta repeat Utp12 PF04003.12 EEQ29061.1 - 2.5e-27 95.3 0.0 4e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EEQ29061.1 - 1.7e-23 82.7 0.0 0.0043 17.3 0.0 9.6 5 2 6 11 11 11 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ29061.1 - 9.9e-10 37.9 1.2 0.23 10.4 0.0 5.4 4 2 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEQ29061.1 - 3.8e-07 29.1 3.4 0.72 8.4 0.0 5.1 3 2 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 EEQ29061.1 - 4e-07 30.1 0.9 0.036 13.9 0.0 5.2 6 1 0 7 7 7 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EEQ29061.1 - 0.0053 14.8 0.0 1.1 7.2 0.0 2.3 2 0 0 2 2 2 2 IKI3 family ELYS-bb PF16687.5 EEQ29061.1 - 0.0086 14.7 0.0 0.065 11.8 0.0 2.3 3 0 0 3 3 3 1 beta-propeller of ELYS nucleoporin PD40 PF07676.12 EEQ29061.1 - 0.037 14.0 0.1 36 4.5 0.0 4.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 EEQ29061.1 - 0.06 12.4 0.0 4 6.4 0.0 3.3 4 0 0 4 4 4 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 EEQ29061.1 - 0.061 11.8 0.0 1.7 7.1 0.0 3.1 3 1 0 3 3 3 0 Cytochrome D1 heme domain Pox_T4_N PF04491.12 EEQ29061.1 - 0.2 11.6 0.4 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus PQQ_3 PF13570.6 EEQ29061.1 - 2.7 8.6 5.4 61 4.3 0.0 4.9 5 0 0 5 5 4 0 PQQ-like domain SKIP_SNW PF02731.15 EEQ29062.1 - 9.6e-72 239.9 5.7 9.6e-72 239.9 5.7 2.4 3 0 0 3 3 3 1 SKIP/SNW domain LRIF1 PF15741.5 EEQ29062.1 - 0.35 9.3 10.4 0.54 8.7 10.4 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Mito_fiss_reg PF05308.11 EEQ29063.1 - 0.21 11.7 5.6 0.26 11.3 5.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EEQ29063.1 - 4.7 6.6 10.2 6.2 6.2 10.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3395 PF11875.8 EEQ29064.1 - 2.2e-38 131.6 0.0 2.2e-38 131.6 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EEQ29064.1 - 2.2e-16 59.7 0.3 4.3e-16 58.8 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain DUF530 PF04409.12 EEQ29064.1 - 0.1 11.0 0.1 0.39 9.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF530) NAAA-beta PF15508.6 EEQ29065.1 - 4.2e-10 39.8 0.1 8.8e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase BCS1_N PF08740.11 EEQ29066.1 - 6.8e-41 140.3 2.2 1.5e-40 139.2 2.2 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EEQ29066.1 - 1.3e-15 58.0 0.0 1.3e-06 28.9 0.0 2.5 1 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEQ29066.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEQ29066.1 - 0.031 14.6 0.2 0.18 12.2 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 EEQ29066.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC DSPc PF00782.20 EEQ29067.1 - 1.3e-16 60.7 0.0 1.5e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain HemS PF05171.12 EEQ29067.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain Glyco_hydro_61 PF03443.14 EEQ29070.1 - 8.5e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 UPF0029 PF01205.19 EEQ29072.1 - 6.8e-35 119.6 0.0 1.2e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EEQ29072.1 - 0.0024 18.1 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF4113 PF13438.6 EEQ29072.1 - 0.15 12.1 0.0 0.7 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) Pkinase PF00069.25 EEQ29073.1 - 5e-14 52.3 0.0 8.1e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29073.1 - 0.095 12.0 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Dynamin_N PF00350.23 EEQ29074.1 - 1.1e-31 110.1 0.1 2e-31 109.3 0.1 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EEQ29074.1 - 1.1e-17 64.1 0.0 3e-16 59.5 0.0 2.2 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 EEQ29074.1 - 1.7e-05 24.9 1.6 0.0014 18.8 0.1 2.9 2 1 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EEQ29074.1 - 0.0015 18.6 0.3 0.0074 16.4 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EEQ29074.1 - 0.27 10.5 1.5 1.8 7.8 0.1 2.5 3 0 0 3 3 3 0 AIG1 family WD40 PF00400.32 EEQ29075.1 - 0.029 15.2 22.1 1.3 10.0 0.0 7.9 8 0 0 8 8 8 0 WD domain, G-beta repeat Mito_carr PF00153.27 EEQ29076.1 - 1.8e-56 188.1 2.1 2.4e-18 65.9 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 EEQ29076.1 - 0.038 13.9 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 UcrQ family HMD PF03201.16 EEQ29076.1 - 0.044 14.0 0.0 5.4 7.3 0.0 3.4 3 1 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF3278 PF11683.8 EEQ29076.1 - 0.1 12.7 0.0 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Flt3_lig PF02947.14 EEQ29077.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 flt3 ligand Homeodomain PF00046.29 EEQ29080.1 - 0.00023 20.9 0.6 0.57 10.1 0.0 2.9 3 0 0 3 3 3 2 Homeodomain DUF2408 PF10303.9 EEQ29080.1 - 1.4 9.5 4.2 1.6 9.3 0.6 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2408) Beta-lactamase PF00144.24 EEQ29082.1 - 4.3e-32 111.7 0.0 6e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Ras PF00071.22 EEQ29083.1 - 1.2e-65 220.1 0.6 1.4e-65 219.8 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ29083.1 - 6.6e-36 123.2 0.2 1.2e-35 122.3 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ29083.1 - 1.6e-16 60.3 0.1 1.9e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEQ29083.1 - 2.2e-05 24.5 0.0 9.2e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ29083.1 - 2.3e-05 24.4 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EEQ29083.1 - 0.00015 21.4 0.4 0.00041 19.9 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EEQ29083.1 - 0.00023 20.6 0.1 0.0003 20.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 EEQ29083.1 - 0.00043 20.7 0.0 0.18 12.3 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EEQ29083.1 - 0.00086 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EEQ29083.1 - 0.0042 16.6 0.1 0.023 14.2 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EEQ29083.1 - 0.0085 16.5 0.0 0.011 16.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ29083.1 - 0.026 14.8 0.0 0.067 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EEQ29083.1 - 0.033 13.5 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 EEQ29083.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EEQ29083.1 - 0.064 13.8 0.1 0.15 12.6 0.1 1.8 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 EEQ29083.1 - 0.067 12.6 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EEQ29083.1 - 0.072 13.1 0.1 0.2 11.6 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EEQ29083.1 - 0.076 12.6 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEQ29083.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EEQ29083.1 - 0.089 12.5 0.1 1.2 8.8 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ERAP1_C PF11838.8 EEQ29084.1 - 1.2e-89 301.0 0.1 2.1e-89 300.2 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EEQ29084.1 - 6.8e-84 280.8 5.0 1.1e-83 280.1 5.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EEQ29084.1 - 1.8e-37 129.3 0.1 8.9e-37 127.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Ssl1 PF04056.14 EEQ29085.1 - 9.7e-73 244.1 0.0 1.3e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EEQ29085.1 - 1.3e-18 67.0 8.5 1.3e-18 67.0 8.5 2.4 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EEQ29085.1 - 2.1e-14 54.1 0.0 5.8e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.14 EEQ29085.1 - 0.001 18.7 4.2 0.001 18.7 4.2 2.1 2 0 0 2 2 2 1 Transcription factor Tfb4 YL1 PF05764.13 EEQ29085.1 - 0.055 13.6 9.6 0.072 13.2 9.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein U1snRNP70_N PF12220.8 EEQ29085.1 - 0.4 11.4 3.2 0.74 10.5 3.2 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DZR PF12773.7 EEQ29085.1 - 1.1 9.3 19.2 2 8.5 5.7 2.9 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 EEQ29085.1 - 4.2 8.2 15.8 0.32 11.8 7.7 2.4 1 1 1 2 2 2 0 zinc-ribbon family CDC45 PF02724.14 EEQ29085.1 - 8 4.6 6.7 10 4.3 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NUDIX PF00293.28 EEQ29086.1 - 5.9e-06 26.4 0.3 9.1e-06 25.7 0.3 1.4 1 1 0 1 1 1 1 NUDIX domain DUF1918 PF08940.11 EEQ29086.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF5572 PF17733.1 EEQ29087.1 - 5.7e-25 86.9 1.6 8.9e-25 86.3 0.2 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5572) PUF PF00806.19 EEQ29088.1 - 6.8e-36 120.0 1.1 5.8e-06 25.7 0.0 8.7 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat RraB PF06877.11 EEQ29088.1 - 0.012 16.3 0.2 0.052 14.3 0.0 2.1 3 0 0 3 3 3 0 Regulator of ribonuclease activity B FliJ PF02050.16 EEQ29088.1 - 0.97 9.7 10.8 0.5 10.6 2.3 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Peptidase_S9 PF00326.21 EEQ29089.1 - 0.00016 21.2 0.1 0.00028 20.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family TPT PF03151.16 EEQ29090.1 - 4.8e-58 196.8 16.7 5.8e-58 196.5 16.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EEQ29090.1 - 1.6e-05 25.1 35.4 0.00033 20.8 12.3 2.9 2 1 0 2 2 2 2 EamA-like transporter family PSII PF00421.19 EEQ29090.1 - 2.4e-05 23.2 0.0 4.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Photosystem II protein UAA PF08449.11 EEQ29090.1 - 0.0023 17.2 15.5 0.059 12.6 6.4 2.2 2 0 0 2 2 2 2 UAA transporter family Molybdopterin PF00384.22 EEQ29091.1 - 3e-70 237.4 0.0 8.7e-68 229.2 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EEQ29091.1 - 3e-19 68.8 0.2 8.2e-19 67.4 0.2 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 EEQ29091.1 - 6.6e-19 68.3 0.1 1.7e-18 67.1 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EEQ29091.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EEQ29091.1 - 5.3e-08 32.7 0.6 5.3e-08 32.7 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 EEQ29091.1 - 0.12 12.2 1.1 3.5 7.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 EEQ29091.1 - 0.23 11.5 2.0 4.8 7.3 2.0 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster XRCC4 PF06632.12 EEQ29092.1 - 2.4e-10 39.8 16.0 4.4e-10 38.9 16.0 1.4 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.8 EEQ29092.1 - 0.0055 16.8 4.8 0.013 15.7 4.8 1.6 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain ssDNA_DBD PF18333.1 EEQ29092.1 - 0.12 12.5 1.7 0.39 10.8 1.3 2.0 1 1 1 2 2 2 0 Non-canonical single-stranded DNA-binding domain Integrase_H2C2 PF17921.1 EEQ29096.1 - 1.2e-07 31.7 0.8 1.2e-07 31.7 0.8 2.7 4 0 0 4 4 4 1 Integrase zinc binding domain ER_lumen_recept PF00810.18 EEQ29097.1 - 6.8e-45 153.5 5.7 1.1e-44 152.9 5.7 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EEQ29097.1 - 2.1 8.2 9.3 0.7 9.7 0.2 3.5 4 1 1 5 5 5 0 PQ loop repeat DUF485 PF04341.12 EEQ29097.1 - 2.8 7.9 9.7 0.2 11.6 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function, DUF485 DUF382 PF04037.13 EEQ29099.1 - 2.9e-59 198.8 1.4 2.9e-59 198.8 1.4 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 EEQ29099.1 - 2.5e-20 72.1 3.7 5.5e-20 71.0 3.7 1.6 1 0 0 1 1 1 1 PSP MRP-S33 PF08293.11 EEQ29100.1 - 6.5e-30 103.2 0.1 8.1e-30 102.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.26 EEQ29101.1 - 9.7e-14 51.9 0.0 3.9e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EEQ29101.1 - 8.2e-11 42.2 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EEQ29101.1 - 0.28 11.9 0.0 0.28 11.9 0.0 2.2 2 0 0 2 2 2 0 Double-stranded RNA binding motif RTA1 PF04479.13 EEQ29102.1 - 3.2e-54 183.7 3.1 4.4e-54 183.2 3.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.8 EEQ29103.1 - 6.1e-08 31.9 0.1 9.4e-08 31.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IRS PF02174.17 EEQ29103.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Abhydrolase_1 PF00561.20 EEQ29104.1 - 6.7e-23 81.6 0.0 3.6e-19 69.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ29104.1 - 1.1e-15 58.9 0.0 1.7e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ29104.1 - 5.5e-11 42.2 0.0 1.3e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EEQ29104.1 - 5e-06 26.4 0.5 0.00048 19.9 0.5 2.1 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EEQ29104.1 - 2e-05 24.8 0.0 2.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 EEQ29104.1 - 0.00016 20.5 0.0 0.00042 19.1 0.0 1.6 2 0 0 2 2 2 1 Ndr family Esterase PF00756.20 EEQ29104.1 - 0.00018 21.3 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 EEQ29104.1 - 0.0026 17.6 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) BAAT_C PF08840.11 EEQ29104.1 - 0.0075 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Palm_thioest PF02089.15 EEQ29104.1 - 0.022 14.6 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 EEQ29104.1 - 0.048 12.6 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme UPF0227 PF05728.12 EEQ29104.1 - 0.057 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.11 EEQ29104.1 - 0.06 12.3 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Lipase_2 PF01674.18 EEQ29104.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) DUF3089 PF11288.8 EEQ29104.1 - 0.089 12.3 0.0 0.27 10.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3089) DUF915 PF06028.11 EEQ29104.1 - 0.1 11.9 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_S3Ae PF01015.18 EEQ29105.1 - 1e-84 283.2 5.0 1.2e-84 282.9 5.0 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EEQ29105.1 - 0.015 15.8 0.4 0.064 13.8 0.2 2.1 1 1 1 2 2 2 0 Translation initiation factor SUI1 TipAS PF07739.13 EEQ29105.1 - 0.14 12.7 0.0 1.7 9.2 0.0 2.2 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain GTP_CH_N PF12471.8 EEQ29106.1 - 5.5e-64 215.5 0.0 3.7e-50 170.4 0.0 2.3 1 1 1 2 2 2 2 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EEQ29106.1 - 9e-16 57.9 0.0 1.4e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Limkain-b1 PF11608.8 EEQ29106.1 - 0.16 12.0 0.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 Elf1 PF05129.13 EEQ29107.1 - 0.0014 18.6 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like UPRTase PF14681.6 EEQ29108.1 - 1.1e-78 263.5 0.0 1.3e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EEQ29108.1 - 0.019 14.5 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain WAPL PF07814.13 EEQ29109.1 - 1.6e-84 283.8 2.9 2.7e-84 283.1 2.9 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Baculo_PEP_C PF04513.12 EEQ29110.1 - 0.008 16.2 8.0 0.008 16.2 8.0 2.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EEQ29110.1 - 0.078 13.2 8.7 0.99 9.7 0.1 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Occludin_ELL PF07303.13 EEQ29110.1 - 0.2 12.4 1.0 0.66 10.7 0.1 2.3 2 0 0 2 2 2 0 Occludin homology domain DUF2937 PF11157.8 EEQ29110.1 - 0.26 11.0 1.0 0.5 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FlaC_arch PF05377.11 EEQ29110.1 - 0.93 9.9 4.0 1.3 9.5 0.1 3.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EEQ29110.1 - 1.1 9.3 11.3 0.25 11.4 1.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EEQ29110.1 - 2.4 8.2 8.5 3.9 7.5 0.7 3.0 1 1 0 2 2 2 0 Laminin Domain II Ras PF00071.22 EEQ29111.1 - 3.3e-46 156.8 0.2 3.8e-46 156.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ29111.1 - 1.8e-16 60.5 0.1 2.5e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ29111.1 - 6.8e-07 28.9 0.0 8.3e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ29111.1 - 7.6e-05 22.3 0.2 0.0015 18.1 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEQ29111.1 - 0.00015 21.8 0.1 0.0002 21.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EEQ29111.1 - 0.00098 18.6 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EEQ29111.1 - 0.0021 18.0 0.0 0.44 10.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 EEQ29111.1 - 0.034 13.6 0.0 0.077 12.5 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3568 PF12092.8 EEQ29111.1 - 0.095 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) AAA_14 PF13173.6 EEQ29111.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain tRNA-synt_2b PF00587.25 EEQ29112.1 - 1.8e-29 103.0 0.1 3.6e-29 102.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EEQ29112.1 - 6.3e-19 68.2 4.5 6.3e-19 68.2 4.5 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CAMSAP_CC1 PF17095.5 EEQ29112.1 - 0.089 12.6 2.2 0.2 11.5 2.2 1.5 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin 2-Hacid_dh_C PF02826.19 EEQ29113.1 - 3.3e-50 169.9 0.0 5.1e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ29113.1 - 3.2e-34 117.5 0.0 4.5e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EEQ29113.1 - 9.6e-05 22.6 0.3 0.00021 21.5 0.3 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 EEQ29113.1 - 9.8e-05 22.1 0.1 0.00027 20.6 0.1 1.7 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.21 EEQ29113.1 - 0.0024 18.0 0.1 0.005 16.9 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 EEQ29113.1 - 0.0029 17.2 0.1 0.0095 15.5 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 EEQ29113.1 - 0.007 16.9 0.0 0.031 14.8 0.0 2.0 2 0 0 2 2 2 1 XdhC Rossmann domain DUF1780 PF08682.10 EEQ29113.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) 3HCDH_N PF02737.18 EEQ29113.1 - 0.18 11.7 1.3 2.7 7.8 0.6 2.5 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 EEQ29114.1 - 2.4e-65 220.5 0.0 2.8e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29114.1 - 1.3e-30 106.5 0.0 1.9e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ29114.1 - 0.0033 16.4 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EEQ29114.1 - 0.025 13.9 0.0 0.075 12.3 0.0 1.7 1 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 EEQ29114.1 - 0.036 12.8 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EEQ29114.1 - 0.16 11.5 0.0 5 6.7 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 G_glu_transpept PF01019.21 EEQ29115.1 - 3e-89 300.1 0.0 1e-55 189.5 0.0 2.1 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase NADH_B2 PF14813.6 EEQ29117.1 - 0.00031 20.5 0.1 0.00032 20.4 0.1 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 E1-E2_ATPase PF00122.20 EEQ29118.1 - 8.2e-31 106.9 0.5 1.6e-30 106.0 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 EEQ29118.1 - 6.9e-22 77.9 2.9 2.1e-13 50.5 1.0 2.7 1 1 1 2 2 2 2 P5-type ATPase cation transporter Hydrolase PF00702.26 EEQ29118.1 - 7.4e-15 55.8 0.1 1e-05 25.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ29118.1 - 0.00042 20.3 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EEQ29118.1 - 0.0022 17.6 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEQ29118.1 - 0.02 14.6 0.0 4.5 6.9 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase NAP PF00956.18 EEQ29119.1 - 1.2e-97 326.4 5.8 1.2e-97 326.4 5.8 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Myosin_head PF00063.21 EEQ29120.1 - 7.7e-263 873.7 1.7 1.1e-262 873.3 1.7 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EEQ29120.1 - 3.1e-26 91.6 2.5 3.1e-26 91.6 2.5 3.2 3 1 1 4 4 2 1 DIL domain IQ PF00612.27 EEQ29120.1 - 2.6e-11 42.3 30.8 3.7e-05 23.1 0.6 6.8 6 0 0 6 6 6 3 IQ calmodulin-binding motif GAS PF13851.6 EEQ29120.1 - 0.00072 19.0 13.1 0.00072 19.0 13.1 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding AAA_22 PF13401.6 EEQ29120.1 - 0.0011 19.3 0.1 0.0091 16.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain Myosin_N PF02736.19 EEQ29120.1 - 0.0024 17.7 2.6 0.0064 16.3 2.6 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 EEQ29120.1 - 0.0049 17.3 0.0 0.019 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Spc7 PF08317.11 EEQ29120.1 - 0.014 14.3 19.8 0.018 13.9 18.5 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein T2SSE PF00437.20 EEQ29120.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein CALCOCO1 PF07888.11 EEQ29120.1 - 0.044 12.7 19.7 0.1 11.5 19.7 1.5 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like NACHT PF05729.12 EEQ29120.1 - 0.092 12.7 0.0 1.8 8.5 0.0 2.9 3 0 0 3 3 3 0 NACHT domain TsaE PF02367.17 EEQ29120.1 - 0.11 12.6 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EEQ29120.1 - 0.13 12.6 0.0 0.57 10.6 0.0 2.2 2 0 0 2 2 1 0 RNA helicase EzrA PF06160.12 EEQ29120.1 - 0.16 10.1 15.3 0.39 8.8 2.7 2.4 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA Phage_GP20 PF06810.11 EEQ29120.1 - 0.27 11.0 6.5 1.1 9.1 6.4 2.1 1 1 0 1 1 1 0 Phage minor structural protein GP20 ArAE_2_N PF10337.9 EEQ29120.1 - 0.36 9.8 3.1 0.62 9.0 3.1 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal KASH_CCD PF14662.6 EEQ29120.1 - 1.2 8.9 23.0 0.42 10.4 18.7 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 EEQ29120.1 - 1.7 9.1 12.3 1.3 9.5 0.1 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 EEQ29120.1 - 2.4 8.2 9.2 1 9.4 4.4 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ham1p_like PF01725.16 EEQ29121.1 - 2.3e-57 193.9 0.0 2.6e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 EEQ29122.1 - 4.4e-27 95.2 0.1 9.8e-27 94.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EEQ29122.1 - 4e-07 30.5 0.0 1.2e-06 29.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EEQ29122.1 - 0.0011 19.4 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EEQ29122.1 - 0.0015 18.8 0.0 0.0048 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ29122.1 - 0.0023 18.2 0.0 0.0053 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EEQ29122.1 - 0.0029 17.6 0.0 0.0096 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ29122.1 - 0.0048 17.3 0.1 0.018 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 EEQ29122.1 - 0.006 16.5 0.1 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 NTPase KTI12 PF08433.10 EEQ29122.1 - 0.0084 15.6 0.0 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ADK PF00406.22 EEQ29122.1 - 0.014 15.5 0.1 0.16 12.1 0.0 2.1 2 1 0 2 2 2 0 Adenylate kinase AAA_33 PF13671.6 EEQ29122.1 - 0.017 15.3 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EEQ29122.1 - 0.051 13.4 0.2 7.3 6.4 0.0 2.1 1 1 0 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.22 EEQ29122.1 - 0.055 13.9 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Hydin_ADK PF17213.3 EEQ29122.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain NACHT PF05729.12 EEQ29122.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 EEQ29122.1 - 0.2 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EEQ29122.1 - 0.29 11.5 0.6 0.43 10.9 0.2 1.5 1 1 1 2 2 2 0 AAA domain Peptidase_C78 PF07910.13 EEQ29123.1 - 3.2e-65 219.6 0.0 4.2e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf_UBZ PF18439.1 EEQ29123.1 - 0.0037 16.8 0.0 0.01 15.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EEQ29123.1 - 0.0044 17.3 5.1 0.13 12.6 2.3 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EEQ29123.1 - 9.7 7.3 6.2 28 5.9 3.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger AA_kinase PF00696.28 EEQ29124.1 - 5.4e-42 144.0 0.0 8.7e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EEQ29124.1 - 1.2e-13 50.6 1.2 1.5e-11 43.9 0.2 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EEQ29124.1 - 7.2e-12 44.9 0.1 5.2e-09 35.7 0.1 3.0 3 0 0 3 3 3 2 ACT domain YhfT PF10797.9 EEQ29124.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function zf-Tim10_DDP PF02953.15 EEQ29125.1 - 1e-22 79.5 0.7 1.5e-22 79.0 0.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger G10 PF01125.17 EEQ29126.1 - 1.1e-67 226.3 4.6 1.3e-67 226.2 4.6 1.0 1 0 0 1 1 1 1 G10 protein Forkhead PF00250.18 EEQ29127.1 - 1.8e-33 114.6 0.0 3.1e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Ribosomal_L23eN PF03939.13 EEQ29128.1 - 8e-27 93.2 9.4 1.4e-26 92.5 9.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EEQ29128.1 - 1.2e-13 51.2 1.6 5e-13 49.2 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L23 Bmt2 PF11968.8 EEQ29129.1 - 1.9e-85 286.2 0.0 2.3e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Pkinase PF00069.25 EEQ29130.1 - 3.8e-22 78.9 0.0 7e-17 61.7 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29130.1 - 0.0039 16.5 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase eRF1_2 PF03464.15 EEQ29131.1 - 1.4e-46 158.1 0.0 2.2e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EEQ29131.1 - 3.8e-39 133.7 0.2 7.7e-39 132.7 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EEQ29131.1 - 2.2e-21 76.2 0.0 3.5e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EEQ29131.1 - 5.6e-10 39.6 0.0 1.1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EEQ29131.1 - 1.1e-08 35.4 0.1 1.7e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor PDT PF00800.18 EEQ29132.1 - 2.4e-59 200.2 0.1 3.4e-59 199.7 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EEQ29132.1 - 9.3e-06 25.3 0.0 3.3e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 ACT domain MaoC_dehydratas PF01575.19 EEQ29133.1 - 9.9e-05 21.9 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain Abhydrolase_3 PF07859.13 EEQ29134.1 - 5e-43 147.4 0.0 6.4e-41 140.5 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 EEQ29134.1 - 5.7e-07 28.8 0.6 6.9e-06 25.2 0.6 2.0 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 EEQ29134.1 - 0.084 12.4 0.2 2.3 7.6 0.2 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase DER1 PF04511.15 EEQ29135.1 - 3.3e-27 95.7 2.9 3.8e-27 95.4 2.9 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 EEQ29135.1 - 0.43 10.6 8.4 0.086 12.8 4.1 1.9 2 0 0 2 2 2 0 Rhomboid family Urm1 PF09138.11 EEQ29137.1 - 0.013 15.9 0.0 0.061 13.7 0.0 2.0 1 1 1 2 2 2 0 Urm1 (Ubiquitin related modifier) fn3_PAP PF17808.1 EEQ29137.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase TruB_C_2 PF16198.5 EEQ29138.1 - 3.4e-23 81.6 1.5 6.2e-23 80.7 1.5 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EEQ29138.1 - 2.3e-21 75.5 1.5 5e-21 74.4 1.5 1.6 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 EEQ29138.1 - 1.1e-20 74.5 5.3 3.2e-18 66.5 0.3 4.2 2 2 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 EEQ29138.1 - 0.0058 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain DKCLD PF08068.12 EEQ29138.1 - 0.13 12.4 0.0 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 DKCLD (NUC011) domain RNA_polI_A34 PF08208.11 EEQ29138.1 - 1.9 8.5 29.7 3.2 7.8 29.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Neur_chan_memb PF02932.16 EEQ29138.1 - 7.6 6.5 5.2 11 5.9 5.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OmpH PF03938.14 EEQ29139.1 - 1.2 9.5 15.5 1 9.7 0.2 3.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF812 PF05667.11 EEQ29140.1 - 0.0084 15.1 14.4 0.0055 15.7 9.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF812) DUF16 PF01519.16 EEQ29140.1 - 0.018 15.5 5.8 0.018 15.5 5.8 3.1 3 1 0 3 3 2 0 Protein of unknown function DUF16 HrpB7 PF09486.10 EEQ29140.1 - 0.024 15.0 4.0 0.024 15.0 4.0 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) FliJ PF02050.16 EEQ29140.1 - 0.032 14.5 2.0 0.032 14.5 2.0 4.2 3 2 1 4 4 4 0 Flagellar FliJ protein DUF4600 PF15372.6 EEQ29140.1 - 0.2 12.1 7.2 0.13 12.7 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) HalX PF08663.10 EEQ29140.1 - 0.28 11.5 6.1 1.4 9.3 0.8 3.1 3 1 0 3 3 3 0 HalX domain Spc7 PF08317.11 EEQ29140.1 - 0.55 9.1 17.0 0.087 11.7 8.7 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-Q PF13094.6 EEQ29140.1 - 1.6 9.0 10.9 11 6.2 10.9 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ku_C PF03730.14 EEQ29140.1 - 1.9 9.3 5.7 7 7.4 2.6 2.9 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm TMPIT PF07851.13 EEQ29140.1 - 2 7.6 7.9 4.6 6.4 3.7 2.3 2 0 0 2 2 2 0 TMPIT-like protein PCRF PF03462.18 EEQ29140.1 - 2 8.2 7.8 5.6 6.8 3.1 2.6 2 0 0 2 2 2 0 PCRF domain ApoO PF09769.9 EEQ29140.1 - 2.4 8.2 5.9 16 5.4 1.7 3.4 2 2 2 4 4 4 0 Apolipoprotein O DUF1043 PF06295.12 EEQ29140.1 - 3 7.9 10.3 0.23 11.4 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF725 PF05267.12 EEQ29140.1 - 3.4 7.7 7.7 1.6 8.8 0.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF725) FlaC_arch PF05377.11 EEQ29140.1 - 3.6 8.1 8.0 13 6.3 0.4 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 EEQ29140.1 - 4.3 7.5 15.6 1.1 9.4 10.4 2.5 2 1 0 2 2 2 0 Tropomyosin like DUF4446 PF14584.6 EEQ29140.1 - 7.3 6.6 9.8 3.8 7.5 2.7 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) COG2 PF06148.11 EEQ29140.1 - 8.2 6.5 12.2 6 7.0 0.9 3.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Mt_ATP-synt_D PF05873.12 EEQ29140.1 - 8.3 6.2 8.0 31 4.4 2.1 3.0 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1664 PF07889.12 EEQ29140.1 - 9.9 6.2 12.7 17 5.5 6.1 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) HET PF06985.11 EEQ29141.1 - 1.9e-08 34.8 1.4 1.2e-07 32.2 1.4 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CLTH PF10607.9 EEQ29142.1 - 9.4e-34 116.4 0.7 1.3e-33 116.0 0.1 1.5 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DUF5398 PF17376.2 EEQ29142.1 - 0.013 16.1 0.9 0.91 10.2 0.1 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5398) SKA2 PF16740.5 EEQ29142.1 - 1.7 8.5 6.2 0.15 11.9 0.8 2.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF2431 PF10354.9 EEQ29143.1 - 1.1e-60 204.7 0.0 2.1e-60 203.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) EamA PF00892.20 EEQ29144.1 - 5.4e-06 26.6 7.4 5.4e-06 26.6 7.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family Methyltr_RsmB-F PF01189.17 EEQ29145.1 - 2.7e-73 245.9 0.0 4.2e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EEQ29145.1 - 5.6e-07 30.0 0.0 1.4e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EEQ29145.1 - 0.037 14.1 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Blt1 PF12754.7 EEQ29146.1 - 6.5e-43 146.6 0.6 2.1e-41 141.7 0.6 2.2 1 1 0 1 1 1 1 Blt1 N-terminal domain DUF2340 PF10209.9 EEQ29146.1 - 0.015 15.8 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Pyridox_ox_2 PF12900.7 EEQ29146.1 - 0.036 14.1 0.0 0.059 13.4 0.0 1.4 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Striatin PF08232.12 EEQ29147.1 - 1.1e-45 156.0 5.1 1.1e-45 156.0 5.1 2.7 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 EEQ29147.1 - 9.1e-26 89.6 20.0 2.4e-05 25.0 0.4 8.0 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29147.1 - 9.1e-05 22.7 0.0 5.2 7.4 0.0 4.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ29147.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EEQ29147.1 - 0.14 10.6 0.2 0.31 9.5 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain XPA_C PF05181.12 EEQ29148.1 - 2.8e-26 91.2 2.3 5.7e-26 90.2 2.3 1.6 1 0 0 1 1 1 1 XPA protein C-terminus YhfH PF14149.6 EEQ29148.1 - 0.011 15.7 3.5 0.91 9.6 0.2 2.6 2 0 0 2 2 2 0 YhfH-like protein DUF2406 PF10295.9 EEQ29148.1 - 0.033 14.8 0.6 0.14 12.9 0.6 2.0 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) MAS20 PF02064.15 EEQ29148.1 - 0.41 10.7 5.8 0.095 12.8 2.1 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor ADD_DNMT3 PF17980.1 EEQ29148.1 - 0.76 9.8 3.4 0.31 11.1 0.6 1.7 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 XPA_N PF01286.18 EEQ29148.1 - 2.7 8.1 12.4 0.41 10.7 7.0 2.1 2 0 0 2 2 2 0 XPA protein N-terminal PIG-P PF08510.12 EEQ29149.1 - 7.2e-53 177.6 0.8 7.2e-53 177.6 0.8 1.7 2 0 0 2 2 2 1 PIG-P CDC45 PF02724.14 EEQ29149.1 - 0.011 14.0 0.1 0.016 13.5 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DPM2 PF07297.12 EEQ29149.1 - 0.016 15.5 7.6 0.027 14.7 7.6 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) SDA1 PF05285.12 EEQ29149.1 - 0.023 14.2 5.0 0.028 13.9 5.0 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EEQ29149.1 - 0.079 12.3 7.6 0.1 12.0 7.6 1.2 1 0 0 1 1 1 0 BUD22 HsbA PF12296.8 EEQ29150.1 - 9.7e-28 97.0 7.8 9.7e-28 97.0 7.8 2.2 2 1 1 3 3 3 1 Hydrophobic surface binding protein A Phage_Coat_B PF05356.11 EEQ29150.1 - 0.11 12.4 1.5 0.25 11.3 1.1 1.8 2 0 0 2 2 2 0 Phage Coat protein B DUF3216 PF11505.8 EEQ29150.1 - 0.15 12.3 0.2 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) ApoLp-III PF07464.11 EEQ29150.1 - 0.16 12.1 8.0 0.044 13.9 3.0 2.3 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) MF_alpha_N PF05436.11 EEQ29150.1 - 0.37 10.7 3.0 0.31 11.0 0.6 2.1 2 1 0 2 2 2 0 Mating factor alpha precursor N-terminus Abhydrolase_1 PF00561.20 EEQ29152.1 - 2e-10 40.8 0.5 3.4e-10 40.0 0.3 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ29152.1 - 8.5e-08 33.1 1.2 1e-07 32.8 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UCH PF00443.29 EEQ29153.1 - 4.1e-11 42.9 0.0 9.7e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.6 EEQ29153.1 - 2.9e-10 39.8 11.7 4.9e-10 39.1 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.20 EEQ29153.1 - 3.3e-06 26.7 23.0 0.025 14.4 4.8 4.5 4 0 0 4 4 4 3 MORN repeat Prok-RING_4 PF14447.6 EEQ29153.1 - 0.01 15.7 10.7 0.02 14.7 10.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 USP7_ICP0_bdg PF12436.8 EEQ29153.1 - 0.041 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 CHRD PF07452.12 EEQ29153.1 - 0.16 12.9 2.5 0.64 11.0 2.5 2.1 1 0 0 1 1 1 0 CHRD domain zf-RING_5 PF14634.6 EEQ29153.1 - 0.41 10.7 12.2 0.8 9.7 12.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EEQ29153.1 - 2.2 8.2 9.8 3 7.8 8.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 EEQ29154.1 - 4.5e-14 52.4 0.0 5.7e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29154.1 - 3.3e-07 29.8 0.0 9.4e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EEQ29154.1 - 5.6e-05 22.8 0.0 8.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EEQ29154.1 - 7.9e-05 22.7 0.3 0.00016 21.7 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ29154.1 - 0.00017 21.0 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEQ29154.1 - 0.00068 19.3 0.0 0.0018 17.9 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 EEQ29154.1 - 0.00091 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EEQ29154.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2066 PF09839.9 EEQ29154.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) GH3 PF03321.13 EEQ29155.1 - 0.0038 16.2 0.0 0.24 10.2 0.0 2.0 2 0 0 2 2 2 2 GH3 auxin-responsive promoter Beta_elim_lyase PF01212.21 EEQ29156.1 - 3.6e-59 200.5 0.0 4.5e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EEQ29156.1 - 0.0059 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EEQ29156.1 - 0.018 14.2 0.0 0.022 13.9 0.0 1.3 1 1 0 1 1 1 0 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEQ29156.1 - 0.13 10.8 0.0 0.27 9.7 0.0 1.6 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF4250 PF14056.6 EEQ29156.1 - 0.14 12.2 0.1 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Aminotran_3 PF00202.21 EEQ29156.1 - 0.18 10.5 0.0 0.29 9.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III MFS_1 PF07690.16 EEQ29157.1 - 4.8e-39 134.3 26.2 4.8e-39 134.3 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ29157.1 - 2.7e-15 56.2 0.1 2.7e-15 56.2 0.1 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EEQ29157.1 - 0.00041 18.9 1.7 0.00068 18.2 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_2 PF00891.18 EEQ29158.1 - 4.3e-21 75.2 0.0 6.4e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain p450 PF00067.22 EEQ29159.1 - 4.9e-48 164.0 0.0 7.1e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AalphaY_MDB PF04611.12 EEQ29159.1 - 0.045 13.8 0.0 0.094 12.7 0.0 1.5 1 1 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Cyt-b5 PF00173.28 EEQ29160.1 - 8.6e-16 57.9 0.0 1.8e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC2_membrane PF01061.24 EEQ29161.1 - 1.6e-84 282.5 59.7 2.3e-43 148.1 24.2 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 EEQ29161.1 - 3.1e-31 107.1 5.4 1.7e-26 92.0 1.1 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 EEQ29161.1 - 1.2e-22 81.0 0.0 2.9e-14 53.8 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 EEQ29161.1 - 2.5e-13 50.4 0.2 6.7e-13 49.1 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal SMC_N PF02463.19 EEQ29161.1 - 0.025 14.0 0.0 2.2 7.7 0.0 2.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Ncstrn_small PF18266.1 EEQ29161.1 - 0.072 13.1 1.1 11 6.0 0.4 2.5 2 0 0 2 2 2 0 Nicastrin small lobe ABC2_membrane_3 PF12698.7 EEQ29161.1 - 0.096 11.8 44.7 0.68 9.0 20.7 3.0 2 2 0 2 2 2 0 ABC-2 family transporter protein HalX PF08663.10 EEQ29161.1 - 0.18 12.2 1.3 6.3 7.2 0.1 2.3 2 0 0 2 2 2 0 HalX domain Fungal_trans PF04082.18 EEQ29162.1 - 0.00073 18.6 0.4 0.0017 17.5 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain HSBP1 PF06825.12 EEQ29162.1 - 0.87 9.5 4.7 0.73 9.7 1.0 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DS PF01916.17 EEQ29163.1 - 1.1e-129 431.8 0.0 1.3e-129 431.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.31 EEQ29164.1 - 5.8e-17 61.6 0.0 1.3e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ29164.1 - 1.5e-06 28.3 0.1 0.052 13.8 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EEQ29164.1 - 0.00011 22.1 0.0 0.00011 22.1 0.0 3.6 4 0 0 4 4 4 1 Myb DNA-binding like HeLo PF14479.6 EEQ29166.1 - 3.1e-49 167.6 1.3 4.4e-49 167.1 0.2 1.9 2 0 0 2 2 2 1 Prion-inhibition and propagation TPR_10 PF13374.6 EEQ29166.1 - 7.8e-48 159.1 12.3 2.5e-07 30.3 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ29166.1 - 2.8e-40 136.5 18.2 2.6e-11 43.6 0.6 6.1 3 1 3 7 7 6 6 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ29166.1 - 4.2e-13 49.4 10.3 5.4e-07 29.3 3.3 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 EEQ29166.1 - 9.1e-12 44.1 10.5 0.32 11.1 0.1 8.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ29166.1 - 1.1e-09 37.7 13.6 0.26 11.5 1.2 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.22 EEQ29166.1 - 1e-06 28.2 0.0 2.9e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 EEQ29166.1 - 5e-05 23.2 4.3 2.2 8.7 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ29166.1 - 0.00044 20.0 11.3 3.3 7.7 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 EEQ29166.1 - 0.0062 17.0 11.9 0.53 11.1 0.7 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ29166.1 - 0.0074 16.8 13.0 0.13 12.8 1.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat IGPS PF00218.21 EEQ29166.1 - 0.068 12.3 3.6 0.047 12.9 0.6 2.3 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase TPR_16 PF13432.6 EEQ29166.1 - 0.076 13.7 11.8 3.5 8.3 0.7 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 EEQ29166.1 - 0.11 12.8 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain ANAPC3 PF12895.7 EEQ29166.1 - 0.23 11.7 3.7 6.6 7.0 0.5 3.9 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EEQ29166.1 - 0.45 11.5 11.3 67 4.7 0.2 5.8 5 0 0 5 5 4 0 Tetratricopeptide repeat NmrA PF05368.13 EEQ29167.1 - 1.7e-56 191.4 0.1 2.2e-56 191.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EEQ29167.1 - 2.7e-21 76.3 0.1 3.9e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EEQ29167.1 - 7.1e-07 28.5 0.2 1e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EEQ29167.1 - 0.021 15.1 0.2 0.033 14.4 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EEQ29167.1 - 0.036 13.5 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AIG1 PF04548.16 EEQ29167.1 - 0.064 12.6 0.2 0.099 12.0 0.2 1.2 1 0 0 1 1 1 0 AIG1 family Guanylate_kin PF00625.21 EEQ29167.1 - 0.18 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase Pox_RNA_pol_35 PF03396.15 EEQ29168.1 - 0.088 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 35 kD subunit Qn_am_d_aIV PF09100.10 EEQ29170.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV Ank_2 PF12796.7 EEQ29171.1 - 2.3e-61 204.3 0.2 3.4e-14 53.2 0.4 7.5 3 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ29171.1 - 3.9e-50 167.6 2.0 2.8e-08 34.1 0.0 9.9 3 1 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ29171.1 - 1.7e-46 150.8 8.7 2.1e-05 24.6 0.1 13.4 14 0 0 14 14 12 8 Ankyrin repeat Ank PF00023.30 EEQ29171.1 - 9.8e-46 152.3 19.3 3e-06 27.4 0.6 11.5 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 EEQ29171.1 - 2.6e-42 142.3 9.8 3.3e-11 43.2 0.0 9.7 5 2 6 11 11 11 7 Ankyrin repeats (many copies) NACHT PF05729.12 EEQ29171.1 - 3.2e-08 33.7 0.1 7.6e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EEQ29171.1 - 9.2e-06 26.1 0.0 4.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EEQ29171.1 - 0.00012 22.4 0.0 0.00038 20.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 EEQ29171.1 - 0.0013 19.2 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Fer4_14 PF13394.6 EEQ29171.1 - 0.0047 17.0 0.0 0.07 13.3 0.0 2.5 2 0 0 2 2 2 1 4Fe-4S single cluster domain NB-ARC PF00931.22 EEQ29171.1 - 0.0083 15.3 0.2 0.026 13.7 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 EEQ29171.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_M35 PF02102.15 EEQ29172.1 - 5.5e-105 351.2 16.5 6.1e-105 351.0 16.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EEQ29172.1 - 2.7e-42 144.7 3.2 5.8e-42 143.7 3.2 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Big_11 PF18200.1 EEQ29172.1 - 0.043 13.7 0.8 6.8 6.7 0.0 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain DUF5442 PF17514.2 EEQ29172.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5442) MINDY_DUB PF04424.13 EEQ29173.1 - 5.4e-19 68.3 0.0 8.9e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase Gcd10p PF04189.13 EEQ29174.1 - 2.9e-111 371.4 0.0 1.4e-108 362.6 0.0 2.1 1 1 0 1 1 1 1 Gcd10p family AroM PF07302.11 EEQ29174.1 - 0.15 11.5 0.0 2.1 7.7 0.0 2.6 1 1 1 2 2 2 0 AroM protein Ank_4 PF13637.6 EEQ29178.1 - 9.1e-24 83.5 0.9 3.5e-06 27.4 0.0 5.4 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ29178.1 - 2.1e-14 53.4 0.8 0.00075 19.8 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ29178.1 - 1e-13 51.7 0.2 0.00049 20.6 0.0 4.0 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EEQ29178.1 - 2.5e-12 46.6 0.0 0.049 14.1 0.0 5.6 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EEQ29178.1 - 7.9e-12 44.3 0.3 0.4 11.4 0.0 7.0 8 0 0 8 8 8 4 Ankyrin repeat Pectate_lyase_3 PF12708.7 EEQ29179.1 - 1.8e-98 328.6 7.4 2.9e-83 278.9 3.9 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EEQ29179.1 - 6.8e-07 28.9 3.1 0.025 14.3 0.3 3.5 3 1 0 3 3 3 2 N terminal extension of bacteriophage endosialidase LysM PF01476.20 EEQ29179.1 - 7.6e-06 25.9 0.0 0.18 11.9 0.0 3.7 3 0 0 3 3 3 2 LysM domain Glyco_hydro_18 PF00704.28 EEQ29180.1 - 8.9e-59 199.7 0.6 1.4e-58 199.1 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EEQ29180.1 - 0.018 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Chitin_bind_1 PF00187.19 EEQ29180.1 - 0.072 13.6 0.3 0.072 13.6 0.3 4.6 5 1 1 6 6 6 0 Chitin recognition protein DUF5316 PF17247.2 EEQ29181.1 - 0.24 11.4 0.0 0.24 11.4 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5316) Methyltransf_11 PF08241.12 EEQ29182.1 - 4.8e-19 68.8 0.1 7e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EEQ29182.1 - 1.7e-18 66.9 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EEQ29182.1 - 6.1e-17 62.1 0.0 9.3e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ29182.1 - 3e-16 59.7 0.0 4.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ29182.1 - 1.9e-14 53.7 0.0 2.5e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ29182.1 - 8e-14 52.2 0.1 1.2e-13 51.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ29182.1 - 6.1e-09 35.5 0.0 1.5e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EEQ29182.1 - 6.6e-07 29.3 0.0 9.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EEQ29182.1 - 4.3e-06 26.3 0.0 5.5e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 EEQ29182.1 - 1.2e-05 25.2 0.2 1.6e-05 24.8 0.2 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EEQ29182.1 - 6.8e-05 22.5 0.1 9.9e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EEQ29182.1 - 6.8e-05 22.5 0.1 9.4e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 EEQ29182.1 - 8.3e-05 22.6 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EEQ29182.1 - 0.00023 20.8 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 EEQ29182.1 - 0.00028 20.3 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.11 EEQ29182.1 - 0.00048 19.9 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) N2227 PF07942.12 EEQ29182.1 - 0.0015 17.8 0.2 0.1 11.8 0.1 2.1 1 1 1 2 2 2 1 N2227-like protein Methyltransf_9 PF08003.11 EEQ29182.1 - 0.0023 16.9 0.0 0.003 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) GCD14 PF08704.10 EEQ29182.1 - 0.0032 17.2 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit UPF0020 PF01170.18 EEQ29182.1 - 0.0053 16.5 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PAS_3 PF08447.12 EEQ29182.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold Methyltransf_24 PF13578.6 EEQ29182.1 - 0.032 15.2 0.2 0.12 13.4 0.1 1.9 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 EEQ29182.1 - 0.053 13.5 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EEQ29182.1 - 0.12 11.9 0.1 0.33 10.4 0.1 1.7 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain NmrA PF05368.13 EEQ29183.1 - 7e-17 61.8 0.1 9.8e-17 61.3 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EEQ29183.1 - 3.9e-16 59.5 0.0 6.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EEQ29183.1 - 3.4e-09 37.0 0.3 5.4e-09 36.4 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EEQ29183.1 - 1.3e-06 28.5 0.2 2.4e-06 27.7 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EEQ29183.1 - 6.6e-05 22.5 0.2 0.0001 21.9 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EEQ29183.1 - 8.7e-05 22.9 0.1 0.00016 22.1 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EEQ29183.1 - 0.00056 19.0 0.1 0.00092 18.3 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 EEQ29183.1 - 0.0031 17.6 0.2 0.0047 17.0 0.2 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 EEQ29183.1 - 0.0032 16.6 0.3 0.005 16.0 0.3 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 EEQ29183.1 - 0.0037 17.5 0.4 0.0081 16.4 0.4 1.6 2 0 0 2 2 1 1 TrkA-N domain Pallilysin PF18663.1 EEQ29183.1 - 0.0069 16.4 0.9 0.022 14.8 0.1 2.2 2 1 1 3 3 2 1 Pallilysin beta barrel domain Gp_dh_N PF00044.24 EEQ29183.1 - 0.01 16.2 0.1 0.019 15.3 0.1 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EEQ29183.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 EEQ29183.1 - 0.015 14.4 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EEQ29183.1 - 0.035 14.0 0.1 0.056 13.3 0.1 1.3 1 0 0 1 1 1 0 KR domain GFO_IDH_MocA PF01408.22 EEQ29183.1 - 0.11 13.3 0.1 0.18 12.6 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short PF00106.25 EEQ29183.1 - 0.33 10.4 1.9 0.75 9.2 0.9 1.8 1 1 1 2 2 2 0 short chain dehydrogenase P21-Arc PF04062.14 EEQ29184.1 - 1.1e-73 246.9 0.0 1.3e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Rep_fac_C PF08542.11 EEQ29185.1 - 3e-17 62.8 0.0 1.8e-16 60.3 0.0 2.3 3 0 0 3 3 1 1 Replication factor C C-terminal domain AAA PF00004.29 EEQ29185.1 - 1.4e-16 61.1 0.3 3.1e-16 60.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EEQ29185.1 - 8.4e-13 48.4 0.0 4.2e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EEQ29185.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EEQ29185.1 - 6e-08 32.9 0.0 2.7e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 EEQ29185.1 - 3.8e-07 30.1 0.0 7.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 EEQ29185.1 - 1e-06 28.6 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEQ29185.1 - 2.6e-06 27.9 0.1 4.2e-05 24.0 0.0 2.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 EEQ29185.1 - 4.9e-06 26.5 0.1 9.5e-06 25.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEQ29185.1 - 5.1e-06 26.8 0.4 0.00015 22.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EEQ29185.1 - 1.5e-05 25.0 0.3 6.2e-05 23.0 0.1 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EEQ29185.1 - 5.8e-05 22.4 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EEQ29185.1 - 8.4e-05 22.4 0.0 0.00022 21.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EEQ29185.1 - 0.00026 20.8 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EEQ29185.1 - 0.00028 20.8 0.0 0.00074 19.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EEQ29185.1 - 0.00087 19.3 0.0 0.079 13.0 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEQ29185.1 - 0.00088 19.6 0.0 0.0032 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EEQ29185.1 - 0.0011 19.1 0.0 0.0027 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EEQ29185.1 - 0.003 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain PhoH PF02562.16 EEQ29185.1 - 0.0031 17.0 0.2 0.58 9.6 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 EEQ29185.1 - 0.0063 16.3 0.0 0.036 13.8 0.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_28 PF13521.6 EEQ29185.1 - 0.0066 16.7 0.0 0.034 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ29185.1 - 0.0079 16.7 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EEQ29185.1 - 0.023 14.1 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EEQ29185.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MiaE PF06175.11 EEQ29185.1 - 0.036 13.7 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) ATPase_2 PF01637.18 EEQ29185.1 - 0.043 13.7 0.0 0.083 12.8 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EEQ29185.1 - 0.047 13.1 0.2 0.25 10.7 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EEQ29185.1 - 0.053 13.1 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EEQ29185.1 - 0.057 12.6 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cullin_Nedd8 PF10557.9 EEQ29185.1 - 0.061 13.4 0.1 18 5.5 0.0 2.9 3 0 0 3 3 2 0 Cullin protein neddylation domain RNA_helicase PF00910.22 EEQ29185.1 - 0.071 13.5 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TAFII28 PF04719.14 EEQ29185.1 - 0.18 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Peptidase_M19 PF01244.21 EEQ29186.1 - 1.8e-108 362.5 0.0 2.1e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Synaptobrevin PF00957.21 EEQ29186.1 - 0.22 11.4 0.1 0.61 9.9 0.1 1.7 1 0 0 1 1 1 0 Synaptobrevin His_Phos_2 PF00328.22 EEQ29187.1 - 3.8e-07 29.8 0.1 1.5e-05 24.5 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) EST1 PF10374.9 EEQ29187.1 - 0.01 16.5 1.1 0.016 15.9 1.1 1.4 1 1 0 1 1 1 1 Telomerase activating protein Est1 Pkinase PF00069.25 EEQ29189.1 - 3e-14 53.0 0.0 4.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29189.1 - 2.4e-10 40.1 0.0 3.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EEQ29189.1 - 0.0021 17.6 0.1 0.0035 17.0 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pro_isomerase PF00160.21 EEQ29190.1 - 2e-39 135.4 0.0 4.8e-39 134.2 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lin-8 PF03353.15 EEQ29190.1 - 1.5 8.3 10.1 0.24 10.9 5.8 1.7 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist PARM PF17061.5 EEQ29190.1 - 2.1 8.4 15.8 3.2 7.8 15.8 1.3 1 0 0 1 1 1 0 PARM R3H PF01424.22 EEQ29191.1 - 8.8e-10 38.4 0.0 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EEQ29191.1 - 1.4e-05 24.8 0.1 2.8e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAS_C PF12026.8 EEQ29191.1 - 0.23 11.5 1.7 0.36 10.9 1.7 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain APH PF01636.23 EEQ29192.1 - 4.5e-11 43.1 0.0 3.1e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family HSF_DNA-bind PF00447.17 EEQ29193.1 - 1.2e-29 102.7 0.4 3.1e-29 101.4 0.4 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EEQ29193.1 - 0.075 13.5 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Ets-domain YabA PF06156.13 EEQ29193.1 - 8.4 7.1 9.2 1.2 9.8 1.9 2.7 2 0 0 2 2 2 0 Initiation control protein YabA Histone_H2A_C PF16211.5 EEQ29195.1 - 1.6e-11 43.7 0.0 2.7e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EEQ29195.1 - 2.4e-11 44.1 0.1 1.8e-10 41.3 0.1 1.9 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEQ29195.1 - 0.14 12.5 0.0 2.2 8.7 0.0 2.1 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pho88 PF10032.9 EEQ29196.1 - 4.3e-77 257.5 0.7 5e-77 257.3 0.7 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4512 PF14975.6 EEQ29196.1 - 0.041 14.7 0.1 0.19 12.5 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) F-box-like PF12937.7 EEQ29197.1 - 6.6e-06 25.9 0.0 3.2e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 F-box-like Gp_dh_C PF02800.20 EEQ29198.1 - 7.1e-71 236.9 0.0 9.9e-71 236.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EEQ29198.1 - 5.9e-38 129.3 0.1 1.3e-37 128.1 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EEQ29198.1 - 0.0015 18.7 0.0 0.0071 16.5 0.0 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 EEQ29198.1 - 0.023 15.5 0.0 6.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 EEQ29198.1 - 0.084 12.2 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arb2 PF09757.9 EEQ29199.1 - 4.7e-94 314.3 5.2 7.2e-94 313.7 5.2 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 EEQ29199.1 - 7.9e-80 268.6 0.1 2e-79 267.3 0.0 1.7 2 1 0 2 2 2 1 Histone deacetylase domain Sugar_tr PF00083.24 EEQ29200.1 - 1.9e-123 412.7 25.1 2.2e-123 412.5 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ29200.1 - 7.8e-22 77.7 36.9 7.9e-16 57.9 17.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EEQ29200.1 - 0.0077 14.7 5.1 0.019 13.4 0.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EEQ29201.1 - 5.5e-30 104.5 39.6 5.5e-30 104.5 39.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M16_M PF16187.5 EEQ29202.1 - 5e-98 327.8 0.1 8.1e-98 327.1 0.1 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EEQ29202.1 - 6.7e-33 113.8 2.0 9.7e-22 77.6 0.5 3.6 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEQ29202.1 - 1.3e-31 110.0 0.2 1.4e-19 70.8 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain PXB PF12828.7 EEQ29202.1 - 0.067 13.2 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 PX-associated NUDIX_2 PF13869.6 EEQ29203.1 - 1.4e-81 272.6 0.0 1.6e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase CoaE PF01121.20 EEQ29204.1 - 3.3e-42 144.2 0.0 4.6e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EEQ29204.1 - 0.026 15.1 0.1 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain 2TM PF13239.6 EEQ29204.1 - 0.07 13.4 0.2 0.07 13.4 0.2 1.7 2 0 0 2 2 2 0 2TM domain MPP6 PF10175.9 EEQ29205.1 - 4.4e-07 30.5 4.8 2.3e-05 24.9 4.8 2.5 1 1 0 1 1 1 1 M-phase phosphoprotein 6 zf-CHCC PF10276.9 EEQ29206.1 - 8e-16 57.8 1.9 1.3e-15 57.1 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger domain ECH_1 PF00378.20 EEQ29207.1 - 4.4e-50 170.3 0.0 5.7e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EEQ29207.1 - 1.1e-22 81.0 0.1 7.9e-22 78.2 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EEQ29207.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 GFA PF04828.14 EEQ29208.1 - 2.5e-08 34.1 1.1 2.5e-08 34.1 1.1 2.2 2 1 1 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme UPF0047 PF01894.17 EEQ29209.1 - 2.2e-38 130.9 0.0 2.5e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Transcrip_act PF04949.13 EEQ29210.1 - 0.0036 17.2 0.3 0.0046 16.9 0.3 1.2 1 0 0 1 1 1 1 Transcriptional activator HEAT_2 PF13646.6 EEQ29210.1 - 0.044 14.2 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 HEAT repeats APH PF01636.23 EEQ29211.1 - 1.3e-17 64.5 0.0 2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ29211.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ29211.1 - 0.00076 18.9 0.0 0.26 10.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 EEQ29211.1 - 0.014 15.0 0.0 0.75 9.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.14 EEQ29211.1 - 0.038 13.2 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Kdo PF06293.14 EEQ29211.1 - 0.13 11.6 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FMO-like PF00743.19 EEQ29212.1 - 1.3e-20 73.3 0.3 1.7e-18 66.4 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EEQ29212.1 - 5.9e-06 25.7 0.0 6.7e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EEQ29212.1 - 1.2e-05 24.8 0.0 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ29212.1 - 3e-05 23.4 0.2 0.00051 19.4 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ29212.1 - 0.00024 21.3 0.1 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EEQ29212.1 - 0.04 13.9 0.0 1.6 8.7 0.0 3.0 3 1 0 3 3 3 0 FAD-NAD(P)-binding GCR1_C PF12550.8 EEQ29212.1 - 0.37 11.1 0.1 0.37 11.1 0.1 2.9 4 0 0 4 4 4 0 Transcriptional activator of glycolytic enzymes PQQ_3 PF13570.6 EEQ29213.1 - 0.34 11.5 1.7 17 6.1 0.1 3.4 3 0 0 3 3 3 0 PQQ-like domain ERG4_ERG24 PF01222.17 EEQ29214.1 - 2.6e-146 487.8 9.0 2.9e-146 487.6 9.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EEQ29214.1 - 3.2e-05 23.6 0.1 9.7e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) zf-CHY PF05495.12 EEQ29215.1 - 5.5e-11 42.8 13.3 1.2e-10 41.7 13.3 1.5 1 1 0 1 1 1 1 CHY zinc finger zinc_ribbon_4 PF13717.6 EEQ29215.1 - 1.2 9.1 11.9 3.3 7.7 0.1 3.3 3 1 0 3 3 3 0 zinc-ribbon domain Proteasome PF00227.26 EEQ29216.1 - 1.5e-54 184.4 0.1 1.8e-54 184.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEQ29216.1 - 2.6e-07 30.2 0.3 1.2e-06 28.1 0.1 2.3 2 1 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 EEQ29216.1 - 0.064 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Aldo_ket_red PF00248.21 EEQ29217.1 - 1.8e-55 188.2 0.1 1e-54 185.8 0.1 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family APH PF01636.23 EEQ29218.1 - 3.6e-08 33.6 0.0 0.0001 22.4 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEQ29218.1 - 0.032 13.6 0.0 5.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEQ29219.1 - 4.1e-54 183.7 0.1 1.3e-45 155.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain FAD_binding_4 PF01565.23 EEQ29219.1 - 1.1e-36 125.7 0.2 2.3e-36 124.6 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Pkinase_Tyr PF07714.17 EEQ29219.1 - 3.9e-36 124.7 0.1 8.2e-32 110.5 0.0 2.5 2 1 1 3 3 3 2 Protein tyrosine kinase FAD-oxidase_C PF02913.19 EEQ29219.1 - 4.5e-35 121.5 0.1 9.5e-35 120.4 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Pkinase_fungal PF17667.1 EEQ29219.1 - 4.1e-05 22.5 0.0 7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEQ29219.1 - 0.0008 18.8 0.1 0.0022 17.4 0.1 1.6 1 1 1 2 2 2 1 Kinase-like ABC1 PF03109.16 EEQ29219.1 - 0.0032 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family TIC20 PF16166.5 EEQ29221.1 - 0.081 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like CAP59_mtransfer PF11735.8 EEQ29222.1 - 7.5e-73 245.2 0.0 9.4e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF4048 PF13257.6 EEQ29223.1 - 7.3e-80 268.5 17.1 7.3e-80 268.5 17.1 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 EEQ29223.1 - 0.012 15.6 5.6 0.025 14.6 5.6 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain PDDEXK_10 PF07788.11 EEQ29223.1 - 0.12 12.3 0.6 0.22 11.5 0.6 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Tim17 PF02466.19 EEQ29224.1 - 6.6e-39 132.7 5.6 9.6e-39 132.2 5.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Oxidored_molyb PF00174.19 EEQ29225.1 - 6.8e-60 201.6 0.0 9.6e-60 201.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EEQ29225.1 - 1.9e-24 86.2 0.4 4e-24 85.2 0.4 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 EEQ29225.1 - 0.56 10.4 0.1 0.56 10.4 0.1 3.4 3 0 0 3 3 3 0 BNR/Asp-box repeat PALP PF00291.25 EEQ29226.1 - 7.3e-68 229.1 0.2 8.7e-68 228.9 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.7 EEQ29227.1 - 2.5e-88 296.1 0.1 3.7e-87 292.2 0.0 2.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EEQ29227.1 - 1.6e-08 34.8 3.4 2.1e-05 24.8 0.3 4.2 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EEQ29227.1 - 3e-06 27.6 1.1 0.66 10.5 0.1 5.1 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 EEQ29227.1 - 3.2e-06 26.9 5.9 0.24 11.8 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 EEQ29227.1 - 0.00016 21.7 0.2 0.0063 16.6 0.0 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 EEQ29227.1 - 0.0094 15.6 0.2 0.74 9.3 0.0 3.1 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II zf-RanBP PF00641.18 EEQ29228.1 - 1.9e-19 68.6 8.4 7.1e-10 38.0 1.5 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.24 EEQ29228.1 - 2.8e-07 31.2 0.0 4.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 EEQ29228.1 - 8e-07 28.8 0.0 1.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gtr1_RagA PF04670.12 EEQ29231.1 - 1.8e-92 308.9 0.1 2.2e-92 308.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EEQ29231.1 - 3.7e-08 33.6 0.0 6.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EEQ29231.1 - 1.7e-07 31.3 0.0 7.4e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 EEQ29231.1 - 1.9e-07 30.7 0.0 3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EEQ29231.1 - 2e-07 30.7 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EEQ29231.1 - 0.011 14.9 2.9 1.7 7.7 1.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 EEQ29231.1 - 0.012 15.3 0.6 0.042 13.6 0.3 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 EEQ29231.1 - 0.013 14.7 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EEQ29231.1 - 0.016 15.7 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EEQ29231.1 - 0.07 13.0 0.4 0.42 10.5 0.1 2.4 3 1 1 4 4 4 0 RsgA GTPase AAA_7 PF12775.7 EEQ29231.1 - 0.095 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1_Xtn PF16897.5 EEQ29231.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AIG1 PF04548.16 EEQ29231.1 - 0.19 11.0 0.2 0.52 9.6 0.1 1.9 2 0 0 2 2 2 0 AIG1 family AA_permease PF00324.21 EEQ29232.1 - 1.5e-122 409.7 43.2 1.8e-122 409.4 43.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ29232.1 - 4.3e-34 118.1 43.9 5.3e-34 117.8 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease RdRP PF05183.12 EEQ29233.1 - 3.8e-109 366.0 0.0 1.7e-106 357.2 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase Opi1 PF08618.10 EEQ29234.1 - 2.1e-46 159.1 12.9 5.2e-33 114.9 7.0 3.3 1 1 2 3 3 3 3 Transcription factor Opi1 LIP PF03583.14 EEQ29237.1 - 3.2e-72 243.2 0.0 4.5e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase LAT PF15234.6 EEQ29238.1 - 0.017 14.9 0.2 0.021 14.6 0.2 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells Peptidase_A22B PF04258.13 EEQ29238.1 - 0.035 13.6 0.2 0.04 13.4 0.2 1.1 1 0 0 1 1 1 0 Signal peptide peptidase Voldacs PF03517.13 EEQ29239.1 - 1.7e-31 109.2 0.9 1.7e-31 109.2 0.9 1.7 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Metallophos PF00149.28 EEQ29241.1 - 2.3e-37 129.5 0.5 6e-37 128.1 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 EEQ29241.1 - 0.08 12.7 0.7 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Abhydrolase_2 PF02230.16 EEQ29243.1 - 3.3e-18 66.3 0.0 4.3e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EEQ29243.1 - 3.5e-05 24.5 0.7 4.4e-05 24.2 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family XylR_N PF06505.11 EEQ29243.1 - 0.027 14.2 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Activator of aromatic catabolism Fungal_trans_2 PF11951.8 EEQ29244.1 - 0.00013 20.9 0.7 0.00019 20.4 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ29244.1 - 0.00015 21.8 3.4 0.00025 21.1 3.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 EEQ29245.1 - 0.0018 18.3 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EEQ29245.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DLH PF01738.18 EEQ29246.1 - 2.6e-05 23.9 0.0 0.0066 16.0 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF1100 PF06500.11 EEQ29246.1 - 3e-05 23.0 0.0 9.6e-05 21.3 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 EEQ29246.1 - 4.2e-05 24.3 0.1 0.00012 22.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ29246.1 - 0.00018 20.8 0.0 0.0048 16.2 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ29246.1 - 0.00032 20.4 0.1 0.47 10.1 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ29246.1 - 0.00056 19.4 0.0 0.0018 17.8 0.0 1.7 1 1 1 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 EEQ29246.1 - 0.0022 17.9 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 EEQ29246.1 - 0.015 14.6 0.1 3.4 6.9 0.0 2.4 1 1 1 2 2 2 0 Secretory lipase AXE1 PF05448.12 EEQ29246.1 - 0.048 12.3 0.0 0.14 10.8 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 EEQ29246.1 - 0.081 13.0 0.1 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain CorA PF01544.18 EEQ29247.1 - 1.3e-09 37.8 0.6 3.7e-09 36.3 0.6 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein 2HCT PF03390.15 EEQ29247.1 - 0.2 10.3 0.1 2 6.9 0.2 2.0 2 0 0 2 2 2 0 2-hydroxycarboxylate transporter family TPR_12 PF13424.6 EEQ29248.1 - 6.2e-15 55.2 5.2 7e-09 35.9 1.2 4.8 4 2 1 5 5 4 2 Tetratricopeptide repeat PGAP1 PF07819.13 EEQ29248.1 - 8.1e-05 22.4 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EEQ29248.1 - 9.9e-05 23.0 0.2 0.00039 21.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family NB-ARC PF00931.22 EEQ29248.1 - 0.00029 20.1 0.0 0.00077 18.7 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain Hydrolase_4 PF12146.8 EEQ29248.1 - 0.0027 17.0 0.0 0.0054 16.0 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 TPR_14 PF13428.6 EEQ29248.1 - 0.0027 18.4 0.4 0.24 12.3 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 EEQ29248.1 - 0.0032 17.9 0.0 0.011 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Cutinase PF01083.22 EEQ29248.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Cutinase TPR_1 PF00515.28 EEQ29248.1 - 0.012 15.4 0.2 24 5.0 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ29248.1 - 0.018 15.1 4.8 55 4.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ29248.1 - 0.019 14.4 1.0 0.037 13.4 1.0 1.4 1 0 0 1 1 1 0 MalT-like TPR region TPR_16 PF13432.6 EEQ29248.1 - 0.032 14.9 3.4 0.59 10.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF676 PF05057.14 EEQ29248.1 - 0.033 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TPR_7 PF13176.6 EEQ29248.1 - 0.056 13.5 0.2 15 5.9 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_8 PF06259.12 EEQ29248.1 - 0.18 11.4 0.0 0.66 9.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase TPR_10 PF13374.6 EEQ29248.1 - 0.21 11.5 12.6 23 5.0 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat HAD_2 PF13419.6 EEQ29249.1 - 7.6e-18 65.2 0.0 1.2e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ29249.1 - 1.2e-08 35.5 0.0 1.4e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ29249.1 - 1.7e-06 28.0 0.0 3.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like R-HINP1I PF11463.8 EEQ29249.1 - 0.082 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease EXS PF03124.14 EEQ29250.1 - 6.3e-65 219.7 19.7 4.4e-55 187.3 13.1 2.1 1 1 1 2 2 2 2 EXS family SPX PF03105.19 EEQ29250.1 - 4.3e-64 217.8 12.0 4.3e-64 217.8 12.0 3.0 2 1 0 2 2 2 1 SPX domain Pox_Ag35 PF03286.14 EEQ29250.1 - 0.22 11.3 3.2 0.5 10.1 3.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_S8 PF00082.22 EEQ29251.1 - 1.1e-37 130.0 3.9 1.5e-37 129.5 3.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ29251.1 - 1.4e-20 73.7 0.2 3.3e-20 72.5 0.2 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 HNH_2 PF13391.6 EEQ29252.1 - 0.00015 21.8 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Mito_carr PF00153.27 EEQ29253.1 - 4.6e-31 106.6 10.2 2.3e-14 53.1 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Spore_YtrH PF14034.6 EEQ29253.1 - 0.12 12.5 1.4 0.99 9.6 0.2 2.9 2 1 1 3 3 3 0 Sporulation protein YtrH Beach PF02138.18 EEQ29254.1 - 6.8e-120 399.6 0.0 1.2e-119 398.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EEQ29254.1 - 3e-09 36.9 0.0 3e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EEQ29254.1 - 1.4e-07 31.8 0.0 5.3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 EEQ29254.1 - 1.7e-07 31.8 3.7 0.011 16.5 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat LysM PF01476.20 EEQ29255.1 - 1.6e-11 44.1 0.4 0.00011 22.2 0.2 2.3 2 0 0 2 2 2 2 LysM domain UPF0203 PF05254.12 EEQ29255.1 - 0.071 13.4 3.3 2.7 8.3 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) NUDE_C PF04880.13 EEQ29255.1 - 2.4 8.6 4.3 3.5 8.1 4.3 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region APH PF01636.23 EEQ29256.1 - 4.3e-11 43.2 0.0 1.2e-10 41.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3958 PF13125.6 EEQ29256.1 - 0.087 13.0 0.9 2.8 8.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) TAL_FSA PF00923.19 EEQ29257.1 - 2.2e-94 316.0 0.1 2.5e-94 315.8 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 EEQ29257.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Sod_Cu PF00080.20 EEQ29258.1 - 1.9e-46 157.7 5.7 2.2e-46 157.5 5.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Fungal_trans PF04082.18 EEQ29259.1 - 2e-15 56.6 0.4 3.6e-15 55.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ29259.1 - 1e-05 25.6 8.4 2.3e-05 24.4 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNase PF00565.17 EEQ29261.1 - 2e-79 263.1 0.6 9.9e-26 90.3 0.0 5.6 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EEQ29261.1 - 1.7e-24 86.2 0.0 4.8e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EEQ29261.1 - 9e-05 21.8 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 EEQ29261.1 - 0.023 15.2 0.1 0.1 13.1 0.1 2.3 1 0 0 1 1 1 0 Agenet domain DUF3297 PF11730.8 EEQ29261.1 - 0.027 14.3 0.0 0.11 12.3 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) CRAL_TRIO PF00650.20 EEQ29262.1 - 9.3e-25 87.2 0.0 1.3e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ29262.1 - 2.9e-08 33.8 0.0 7.6e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AT_hook PF02178.19 EEQ29263.1 - 0.11 12.5 85.2 0.059 13.3 2.8 7.1 8 0 0 8 8 8 0 AT hook motif EMC1_C PF07774.13 EEQ29264.1 - 6.3e-77 258.0 0.0 2.2e-76 256.2 0.0 2.0 3 0 0 3 3 3 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EEQ29264.1 - 3.3e-21 76.0 6.7 1.5e-17 64.0 0.6 2.9 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 EEQ29264.1 - 4.3e-07 29.5 0.5 0.036 14.0 0.0 4.7 4 0 0 4 4 4 2 PQQ enzyme repeat adh_short PF00106.25 EEQ29265.1 - 9.2e-35 119.9 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ29265.1 - 2.7e-28 99.1 0.0 5.1e-28 98.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ29265.1 - 6.8e-06 26.1 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 2 KR domain Aa_trans PF01490.18 EEQ29266.1 - 2.6e-93 313.0 18.4 3.9e-93 312.4 18.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.10 EEQ29266.1 - 0.053 11.8 4.0 0.088 11.0 4.0 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2417 PF10329.9 EEQ29266.1 - 2.4 7.5 14.9 3.6 7.0 0.1 4.0 3 1 1 4 4 4 0 Region of unknown function (DUF2417) Abhydrolase_9_N PF15420.6 EEQ29266.1 - 4.4 7.2 13.5 1.2 9.1 1.5 3.6 4 0 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus Bax1-I PF01027.20 EEQ29267.1 - 2e-55 187.9 28.1 2.3e-55 187.7 28.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.11 EEQ29267.1 - 1 9.2 27.1 5.6 6.8 14.5 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling SLATT_4 PF18186.1 EEQ29267.1 - 1.4 8.6 3.3 0.85 9.2 0.7 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 UQ_con PF00179.26 EEQ29268.1 - 9.5e-39 132.2 0.0 1.2e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEQ29268.1 - 0.012 15.9 0.4 0.021 15.1 0.4 1.6 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 EEQ29268.1 - 0.021 14.5 0.0 0.069 12.8 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Peptidase_M36 PF02128.15 EEQ29269.1 - 7e-150 499.3 0.4 8.8e-150 499.0 0.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EEQ29269.1 - 8e-16 57.6 3.1 1.8e-15 56.5 3.1 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif ABC_tran PF00005.27 EEQ29270.1 - 5.5e-56 188.9 0.2 7.6e-31 107.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ29270.1 - 3.9e-53 180.9 30.6 1.1e-34 120.4 15.4 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EEQ29270.1 - 4.7e-07 29.5 7.4 0.02 14.3 1.5 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEQ29270.1 - 5.5e-07 30.3 1.0 0.00063 20.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EEQ29270.1 - 1.8e-06 28.0 1.1 0.053 13.3 0.1 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EEQ29270.1 - 5.8e-06 26.4 0.1 0.021 14.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ29270.1 - 2.3e-05 24.4 0.3 0.12 12.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EEQ29270.1 - 0.00016 21.4 0.4 0.51 10.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 EEQ29270.1 - 0.00031 20.9 0.4 0.015 15.4 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 EEQ29270.1 - 0.00093 18.8 0.0 0.2 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ29270.1 - 0.0012 19.2 0.9 7.4 6.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EEQ29270.1 - 0.0017 18.7 1.2 3.3 8.1 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain T2SSE PF00437.20 EEQ29270.1 - 0.0033 16.5 0.3 0.03 13.4 0.2 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 EEQ29270.1 - 0.013 15.9 0.3 3.3 8.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EEQ29270.1 - 0.022 14.5 1.9 2.1 8.1 0.0 3.1 4 0 0 4 4 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 EEQ29270.1 - 0.027 13.8 0.4 0.54 9.6 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EEQ29270.1 - 0.03 13.6 0.7 1.9 7.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 EEQ29270.1 - 0.069 12.9 0.0 0.76 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DnaB_C PF03796.15 EEQ29270.1 - 0.072 12.4 0.1 3.5 6.9 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DEAD PF00270.29 EEQ29270.1 - 0.085 12.6 0.1 3.5 7.3 0.0 3.2 4 0 0 4 4 4 0 DEAD/DEAH box helicase AAA_7 PF12775.7 EEQ29270.1 - 0.087 12.3 0.1 16 4.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EEQ29270.1 - 0.098 12.7 0.6 7.2 6.6 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 EEQ29270.1 - 0.1 13.1 0.0 14 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EEQ29270.1 - 0.11 12.4 0.5 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Bac_export_2 PF01312.19 EEQ29270.1 - 0.17 11.1 1.2 0.57 9.3 1.2 1.9 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family TrwB_AAD_bind PF10412.9 EEQ29270.1 - 0.43 9.4 2.7 3.4 6.5 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EEQ29270.1 - 0.46 10.0 2.7 0.93 9.1 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_12 PF13087.6 EEQ29271.1 - 2.3e-35 122.1 0.0 4.4e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEQ29271.1 - 1.7e-23 83.7 0.8 1.1e-22 81.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEQ29271.1 - 4.3e-09 36.4 0.0 2e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EEQ29271.1 - 4.5e-09 36.8 0.0 4.4e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EEQ29271.1 - 2.8e-05 24.0 0.0 0.0057 16.4 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EEQ29271.1 - 0.0023 17.4 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 EEQ29271.1 - 0.0038 16.5 0.0 0.32 10.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EEQ29271.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EEQ29271.1 - 0.02 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase WD40 PF00400.32 EEQ29272.1 - 5.5e-16 58.7 2.5 0.23 12.4 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29272.1 - 0.00078 19.7 0.0 10 6.5 0.0 4.0 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Trypan_PARP PF05887.11 EEQ29272.1 - 0.41 10.6 13.4 0.032 14.2 4.1 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PRP38 PF03371.15 EEQ29274.1 - 2.5e-51 174.0 0.0 3.2e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Tnp_22_trimer PF17489.2 EEQ29274.1 - 0.038 14.0 4.5 0.076 13.0 4.5 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain ZapB PF06005.12 EEQ29274.1 - 1.9 9.0 6.3 0.44 11.0 3.0 1.5 2 0 0 2 2 2 0 Cell division protein ZapB Pkinase_fungal PF17667.1 EEQ29275.1 - 2.3e-110 369.2 0.0 3e-110 368.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EEQ29275.1 - 4.9e-06 26.1 0.0 9.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TACI-CRD2 PF09305.10 EEQ29276.1 - 4.3 7.4 6.6 7.9 6.6 6.4 1.5 1 1 0 1 1 1 0 TACI, cysteine-rich domain Transp_cyt_pur PF02133.15 EEQ29277.1 - 4e-29 101.7 22.9 4e-29 101.7 22.9 1.8 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aa_trans PF01490.18 EEQ29277.1 - 0.0039 16.0 10.4 0.0039 16.0 10.4 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein OppC_N PF12911.7 EEQ29277.1 - 3.6 7.7 6.8 22 5.1 1.2 3.8 2 1 1 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C S_4TM PF18159.1 EEQ29277.1 - 6.9 5.9 7.2 19 4.5 0.0 3.2 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain adh_short PF00106.25 EEQ29278.1 - 4.9e-21 75.1 0.0 6.8e-19 68.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ29278.1 - 3.7e-13 49.6 0.0 6.9e-10 38.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ29278.1 - 6.5e-10 39.2 0.1 1e-09 38.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EEQ29278.1 - 0.0045 16.2 0.0 0.0061 15.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein WSC PF01822.19 EEQ29279.1 - 1.4e-08 34.8 9.7 1.4e-08 34.8 9.7 2.7 2 1 0 2 2 2 1 WSC domain Presenilin PF01080.17 EEQ29279.1 - 0.0061 15.4 2.9 0.008 15.0 2.9 1.3 1 0 0 1 1 1 1 Presenilin Apt1 PF10351.9 EEQ29279.1 - 0.3 9.9 18.3 0.45 9.3 18.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EEQ29279.1 - 2 6.9 22.5 2.7 6.5 22.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF3292 PF11696.8 EEQ29279.1 - 2.2 6.5 6.7 2.9 6.2 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) NitrOD1 PF18549.1 EEQ29281.1 - 0.22 11.5 0.1 1.2 9.1 0.0 2.0 1 1 1 2 2 2 0 Nitrosopumilus output domain 1 MFS_1 PF07690.16 EEQ29282.1 - 6.1e-36 124.1 67.7 9e-27 93.9 34.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ29282.1 - 2.5e-08 32.9 14.0 2.5e-08 32.9 14.0 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein Fungal_trans PF04082.18 EEQ29283.1 - 2.9e-16 59.3 0.1 4.6e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ29283.1 - 3.4e-11 43.1 12.4 8.9e-11 41.7 12.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IMS PF00817.20 EEQ29285.1 - 4.4e-37 127.4 0.0 1.1e-21 77.4 0.0 2.4 2 0 0 2 2 2 2 impB/mucB/samB family zf_UBZ PF18439.1 EEQ29285.1 - 1.6e-11 43.6 0.3 4e-11 42.3 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 EEQ29285.1 - 5.7e-11 43.1 0.0 1.1e-10 42.2 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain ABC1 PF03109.16 EEQ29286.1 - 3.5e-21 75.6 0.1 9.3e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EEQ29286.1 - 0.039 13.9 0.3 0.16 11.9 0.2 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family SAM_2 PF07647.17 EEQ29287.1 - 3.1e-11 43.2 0.1 5.8e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 EEQ29287.1 - 1.6e-07 31.7 0.1 7.6e-07 29.6 0.1 2.2 1 1 0 1 1 1 1 PH domain SAM_1 PF00536.30 EEQ29287.1 - 1.6e-07 31.6 1.0 2.8e-07 30.9 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EEQ29287.1 - 0.002 18.3 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.16 EEQ29287.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PH_6 PF15406.6 EEQ29287.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Fungal_trans_2 PF11951.8 EEQ29289.1 - 2.2e-93 313.1 0.2 3.1e-93 312.7 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ29289.1 - 1.4e-06 28.3 8.8 2.8e-06 27.3 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EEQ29290.1 - 4.7e-13 49.4 21.2 0.00024 21.8 0.8 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29290.1 - 6.7e-11 42.3 0.1 0.021 15.1 0.0 4.6 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain UAF_Rrn10 PF05234.11 EEQ29291.1 - 0.00034 20.9 0.0 0.0006 20.0 0.0 1.4 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Mnd1 PF03962.15 EEQ29292.1 - 1.1e-20 73.7 0.0 4.4e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 EEQ29292.1 - 0.00038 20.5 0.2 0.0014 18.7 0.2 2.0 1 0 0 1 1 1 1 Leucine zipper with capping helix domain HTH_20 PF12840.7 EEQ29292.1 - 0.0012 18.9 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain FapA PF03961.13 EEQ29292.1 - 0.11 11.1 6.3 0.12 10.9 6.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 EEQ29292.1 - 0.14 11.9 16.1 0.18 11.6 4.6 3.4 1 1 2 3 3 3 0 Septum formation initiator SlyX PF04102.12 EEQ29292.1 - 0.38 11.4 9.0 0.64 10.7 3.3 2.8 2 0 0 2 2 2 0 SlyX TraI PF07057.11 EEQ29292.1 - 0.39 10.8 2.0 21 5.2 0.1 3.0 3 0 0 3 3 3 0 DNA helicase TraI V_ATPase_I PF01496.19 EEQ29292.1 - 0.51 8.2 2.4 0.52 8.2 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family U1snRNP70_N PF12220.8 EEQ29292.1 - 2.7 8.7 7.5 6.4 7.5 7.5 1.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DHO_dh PF01180.21 EEQ29293.1 - 3.6e-63 213.5 0.6 6.6e-55 186.4 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EEQ29293.1 - 0.0042 16.2 0.4 0.014 14.4 0.4 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NYAP_N PF15439.6 EEQ29293.1 - 0.16 11.2 1.1 0.22 10.7 1.1 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter APH PF01636.23 EEQ29294.1 - 1.4e-20 74.3 0.0 7.9e-20 71.8 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ29294.1 - 0.0056 15.6 0.0 0.064 12.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EEQ29294.1 - 0.045 13.1 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase LacAB_rpiB PF02502.18 EEQ29295.1 - 1.5e-43 148.2 0.1 1.7e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.8 EEQ29295.1 - 0.037 14.2 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2620 TIM PF00121.18 EEQ29296.1 - 5.9e-40 137.2 0.0 1.5e-39 135.8 0.0 1.6 1 1 0 1 1 1 1 Triosephosphate isomerase TF_Otx PF03529.13 EEQ29297.1 - 0.16 12.3 0.2 0.5 10.8 0.2 1.8 1 0 0 1 1 1 0 Otx1 transcription factor Pkinase PF00069.25 EEQ29298.1 - 1.8e-13 50.5 0.0 3.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29298.1 - 1.6e-09 37.5 0.0 3.2e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EEQ29298.1 - 7.5e-05 22.4 0.0 0.00023 20.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EEQ29298.1 - 0.00028 20.9 0.1 0.0016 18.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family U-box PF04564.15 EEQ29300.1 - 1.9e-23 82.4 0.8 1.1e-22 80.0 0.1 2.2 2 0 0 2 2 2 1 U-box domain TPR_11 PF13414.6 EEQ29300.1 - 2.7e-08 33.4 0.6 2.7e-08 33.4 0.6 2.5 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 EEQ29300.1 - 4.7e-08 33.5 4.4 5.6e-05 23.7 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ29300.1 - 1.5e-07 31.0 7.5 0.0002 21.2 1.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ29300.1 - 7.7e-06 25.5 5.7 8.5e-05 22.2 1.5 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ29300.1 - 1.1e-05 25.9 2.2 0.00036 21.0 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 EEQ29300.1 - 5.6e-05 23.8 5.3 0.00011 22.9 5.3 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_14 PF13428.6 EEQ29300.1 - 0.00033 21.2 0.2 0.36 11.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ29300.1 - 0.00058 20.1 4.2 0.057 13.7 0.7 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-Nse PF11789.8 EEQ29300.1 - 0.008 16.0 0.1 0.031 14.1 0.1 1.9 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EEQ29300.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger TPR_17 PF13431.6 EEQ29300.1 - 0.029 14.7 2.4 0.18 12.3 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat FCH PF00611.23 EEQ29300.1 - 0.036 14.3 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain zf-NOSIP PF15906.5 EEQ29300.1 - 0.038 14.1 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein GlnD_UR_UTase PF08335.11 EEQ29300.1 - 0.061 13.4 0.3 0.1 12.7 0.3 1.3 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase CSF-1 PF05337.11 EEQ29300.1 - 0.15 12.2 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) TPR_10 PF13374.6 EEQ29300.1 - 0.22 11.5 2.8 16 5.6 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat ACBP PF00887.19 EEQ29301.1 - 2.4e-19 69.3 0.2 2.8e-19 69.1 0.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.12 EEQ29302.1 - 8.2e-169 562.0 0.0 9.5e-169 561.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EEQ29302.1 - 0.011 15.6 0.0 0.99 9.3 0.0 2.6 2 0 0 2 2 2 0 PLD-like domain Glyco_hydro_18 PF00704.28 EEQ29303.1 - 8.5e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Aldolase PF01081.19 EEQ29305.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase F-box PF00646.33 EEQ29305.1 - 0.11 12.4 0.5 0.31 11.0 0.5 1.8 1 0 0 1 1 1 0 F-box domain Rab3-GTPase_cat PF13890.6 EEQ29305.1 - 0.12 12.0 1.5 0.26 10.9 1.5 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit AA_permease_2 PF13520.6 EEQ29306.1 - 2.1e-59 201.4 52.3 2.6e-59 201.1 52.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ29306.1 - 7.8e-13 47.8 40.8 1.1e-12 47.3 40.8 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2304 PF10066.9 EEQ29306.1 - 0.29 11.4 9.1 0.85 9.9 1.4 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) ABC_membrane PF00664.23 EEQ29307.1 - 6e-52 177.0 27.2 6.2e-21 75.3 2.3 4.1 3 1 1 4 4 4 4 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ29307.1 - 3e-47 160.6 0.8 5.2e-27 95.0 0.1 3.0 3 0 0 3 3 2 2 ABC transporter MMR_HSR1 PF01926.23 EEQ29307.1 - 2.7e-06 27.4 0.8 0.022 14.8 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EEQ29307.1 - 6.6e-05 22.9 1.5 0.61 9.8 0.1 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EEQ29307.1 - 7.4e-05 23.2 1.3 0.12 12.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 EEQ29307.1 - 0.00028 20.0 1.7 0.21 10.5 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EEQ29307.1 - 0.00036 20.5 0.3 0.43 10.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EEQ29307.1 - 0.0004 20.1 0.5 0.45 10.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EEQ29307.1 - 0.00074 18.8 0.1 0.12 11.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 EEQ29307.1 - 0.001 19.6 3.4 0.33 11.4 0.1 3.2 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 EEQ29307.1 - 0.0016 18.5 2.3 0.23 11.5 0.1 2.8 3 0 0 3 3 2 1 Dynamin family SMC_N PF02463.19 EEQ29307.1 - 0.002 17.6 13.9 0.0086 15.5 1.5 4.5 5 1 0 5 5 4 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EEQ29307.1 - 0.0086 16.2 1.5 0.13 12.4 0.2 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 EEQ29307.1 - 0.017 15.4 1.7 4.6 7.5 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EEQ29307.1 - 0.026 15.1 0.5 6.8 7.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EEQ29307.1 - 0.049 13.4 0.1 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 EEQ29307.1 - 0.063 13.0 2.7 7.7 6.1 0.2 2.9 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 EEQ29307.1 - 0.11 12.8 0.1 25 5.1 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 EEQ29307.1 - 0.12 12.0 0.1 6.6 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EEQ29307.1 - 0.22 11.4 2.8 15 5.4 0.1 2.9 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 3-alpha PF03475.14 EEQ29307.1 - 0.91 9.4 3.4 1.3 8.9 0.1 2.8 3 0 0 3 3 3 0 3-alpha domain AAA_28 PF13521.6 EEQ29307.1 - 3.7 7.8 8.2 0.36 11.1 0.1 3.0 4 0 0 4 4 2 0 AAA domain AAA_30 PF13604.6 EEQ29307.1 - 4.7 6.9 9.8 3.8 7.2 0.2 3.3 4 0 0 4 4 4 0 AAA domain Terpene_synth_C PF03936.16 EEQ29308.1 - 6.3e-09 35.6 0.0 8.1e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Aminotran_3 PF00202.21 EEQ29310.1 - 1.4e-115 386.2 0.0 1.6e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EEQ29310.1 - 0.022 14.0 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_transf_22 PF03901.17 EEQ29311.1 - 3.6e-74 250.5 15.2 1.1e-41 143.5 6.3 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family ArfGap PF01412.18 EEQ29312.1 - 1.1e-36 125.5 0.0 2.2e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Hid1 PF12722.7 EEQ29313.1 - 0.47 8.5 2.2 0.53 8.4 2.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIEZO PF15917.5 EEQ29313.1 - 1.2 8.5 10.5 1.1 8.7 9.7 1.3 1 1 0 1 1 1 0 Piezo DUF4519 PF15012.6 EEQ29313.1 - 2.2 8.5 0.0 2.2 8.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4519) MAP17 PF15807.5 EEQ29313.1 - 5.4 7.3 11.5 3.3 8.0 9.0 1.8 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SET PF00856.28 EEQ29314.1 - 2.4e-06 28.1 3.9 4.7e-06 27.1 0.7 2.8 2 1 0 2 2 2 1 SET domain PHD PF00628.29 EEQ29314.1 - 5e-06 26.3 9.7 1.3e-05 25.0 9.7 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEQ29314.1 - 0.54 9.9 5.6 1 8.9 5.6 1.5 1 0 0 1 1 1 0 PHD-finger ORC4_C PF14629.6 EEQ29315.1 - 3.3e-47 160.7 0.0 5.7e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EEQ29315.1 - 1.4e-19 71.1 1.4 1.1e-18 68.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EEQ29315.1 - 2.1e-06 28.1 0.1 4.9e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EEQ29315.1 - 7.6e-05 23.1 0.2 0.00048 20.6 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EEQ29315.1 - 0.00022 20.5 0.1 0.00041 19.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 EEQ29315.1 - 0.013 15.4 0.2 0.064 13.2 0.2 2.1 1 1 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EEQ29315.1 - 0.015 15.0 0.1 0.054 13.2 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EEQ29315.1 - 0.018 15.4 0.1 0.073 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EEQ29315.1 - 0.045 13.7 0.2 0.59 10.0 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EEQ29315.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EEQ29315.1 - 0.083 12.1 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 EEQ29315.1 - 0.12 12.4 0.0 0.85 9.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain RGS PF00615.19 EEQ29316.1 - 1.2e-29 102.9 0.0 3.3e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 EEQ29316.1 - 1.5e-24 85.8 0.1 6.8e-18 64.5 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73_C PF05179.14 EEQ29317.1 - 7.8e-59 197.9 0.0 1.3e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal 4HBT PF03061.22 EEQ29318.1 - 3.8e-13 49.6 0.0 5.8e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EEQ29318.1 - 2.9e-06 27.7 0.0 3.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily NOT2_3_5 PF04153.18 EEQ29319.1 - 1.2e-27 96.5 1.1 1.7e-27 96.1 0.0 1.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.13 EEQ29320.1 - 3.6e-19 68.7 0.2 5.7e-19 68.0 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.18 EEQ29321.1 - 3.6e-180 599.1 0.0 4.6e-180 598.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SMC_N PF02463.19 EEQ29322.1 - 3.4e-70 235.9 0.0 1.2e-69 234.1 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEQ29322.1 - 7.1e-21 74.7 1.0 5.5e-20 71.8 0.2 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EEQ29322.1 - 1.1e-09 39.2 11.2 1.1e-09 39.2 11.2 6.7 2 2 1 4 4 4 1 AAA domain AAA_21 PF13304.6 EEQ29322.1 - 7.9e-09 35.7 7.4 0.00066 19.6 0.1 3.7 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ29322.1 - 0.0011 18.7 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 EEQ29322.1 - 0.0036 16.9 16.4 0.0036 16.9 16.4 5.6 3 2 2 5 5 5 1 Mechanosensitive ion channel porin domain ABC_tran PF00005.27 EEQ29322.1 - 4.6 7.8 26.2 2 8.9 0.0 5.6 3 2 0 3 3 3 0 ABC transporter CUE PF02845.16 EEQ29323.1 - 4.2e-10 39.1 0.0 6.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 EEQ29323.1 - 0.01 15.5 10.7 0.019 14.6 10.7 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Sld5 PF05916.11 EEQ29324.1 - 3.7e-31 107.8 0.0 1.1e-30 106.3 0.0 1.7 1 1 0 1 1 1 1 GINS complex protein DIE2_ALG10 PF04922.12 EEQ29325.1 - 6.6e-126 420.8 7.8 8.2e-126 420.5 7.8 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family FmiP_Thoc5 PF09766.9 EEQ29326.1 - 8.4e-29 101.0 8.9 1.2e-28 100.4 8.9 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 APG6_N PF17675.1 EEQ29326.1 - 0.011 16.3 14.7 0.13 12.7 6.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region SPATA1_C PF15743.5 EEQ29326.1 - 0.047 13.8 5.0 0.047 13.8 5.0 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus Bestrophin PF01062.21 EEQ29326.1 - 0.28 10.5 0.8 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Casc1_N PF15927.5 EEQ29326.1 - 0.31 10.7 15.8 0.27 10.9 8.0 2.5 2 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DUF4200 PF13863.6 EEQ29326.1 - 0.39 11.1 14.9 0.35 11.3 1.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) CREPT PF16566.5 EEQ29326.1 - 0.62 10.2 9.7 3.2 7.9 2.4 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EEQ29326.1 - 0.85 9.1 13.3 1.8 8.1 2.6 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF349 PF03993.12 EEQ29326.1 - 1.3 9.4 11.4 0.29 11.4 5.5 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) V-SNARE PF05008.15 EEQ29326.1 - 1.6 9.2 12.6 5.1 7.5 0.1 3.5 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Atg14 PF10186.9 EEQ29326.1 - 3.8 6.5 15.5 4.3 6.3 9.6 2.4 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 EEQ29326.1 - 4.8 7.0 13.0 0.69 9.7 0.3 2.7 2 1 1 3 3 3 0 Septum formation initiator DUF4140 PF13600.6 EEQ29326.1 - 6.3 7.3 11.5 4.6 7.7 0.3 2.6 3 0 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 EEQ29326.1 - 6.4 7.5 11.2 9.4 6.9 2.1 2.4 2 1 0 2 2 2 0 Initiation control protein YabA p450 PF00067.22 EEQ29327.1 - 4.2e-47 160.9 0.0 5.6e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HlyIII PF03006.20 EEQ29328.1 - 1.5e-61 208.0 21.7 1.8e-61 207.7 21.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Asr PF06392.11 EEQ29328.1 - 0.045 14.1 0.7 0.082 13.3 0.7 1.4 1 0 0 1 1 1 0 Acid shock protein repeat GlnD_UR_UTase PF08335.11 EEQ29328.1 - 0.28 11.3 5.6 0.92 9.6 0.9 2.2 1 1 1 2 2 2 0 GlnD PII-uridylyltransferase Sugar_tr PF00083.24 EEQ29329.1 - 1.6e-120 403.1 18.5 2.5e-120 402.4 18.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ29329.1 - 1.5e-24 86.6 44.1 6.8e-15 54.8 15.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_25 PF13649.6 EEQ29330.1 - 1.6e-15 57.6 0.0 3.3e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ29330.1 - 8e-15 55.4 0.0 3.5e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ29330.1 - 1.2e-13 51.5 0.0 3e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ29330.1 - 4e-11 43.0 0.0 7.5e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ29330.1 - 4.2e-07 29.9 0.0 6.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ29330.1 - 1.4e-05 24.5 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EEQ29330.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 EEQ29330.1 - 0.00024 20.4 0.0 0.11 11.6 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family TehB PF03848.14 EEQ29330.1 - 0.0011 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 EEQ29330.1 - 0.0064 15.8 0.1 0.0094 15.3 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 EEQ29330.1 - 0.0094 15.8 0.0 0.025 14.4 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_24 PF13578.6 EEQ29330.1 - 0.015 16.3 0.0 0.033 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.10 EEQ29330.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_32 PF13679.6 EEQ29330.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GMC_oxred_N PF00732.19 EEQ29331.1 - 1.1e-50 172.6 0.0 1.5e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EEQ29331.1 - 3.7e-34 118.3 0.0 5.9e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 EEQ29331.1 - 0.0032 16.8 0.2 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ29331.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EEQ29331.1 - 0.046 12.8 1.5 0.54 9.3 0.8 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EEQ29331.1 - 0.049 12.9 0.1 0.088 12.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EEQ29331.1 - 0.049 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ29331.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EEQ29331.1 - 0.17 10.7 0.3 0.24 10.2 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Catalase PF00199.19 EEQ29332.1 - 5.4e-178 591.9 0.1 6.5e-178 591.7 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EEQ29332.1 - 0.0007 19.8 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Diphthamide_syn PF01866.17 EEQ29335.1 - 1.5e-74 251.2 0.0 5.9e-74 249.2 0.0 1.8 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Fe-ADH PF00465.19 EEQ29337.1 - 2.6e-77 260.1 1.0 2.9e-77 259.9 1.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EEQ29337.1 - 3.1e-15 56.5 0.2 4.2e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase ANAPC4_WD40 PF12894.7 EEQ29338.1 - 2.8e-05 24.3 0.0 0.0021 18.3 0.0 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain YL1 PF05764.13 EEQ29338.1 - 0.0018 18.5 3.2 0.0025 18.0 3.2 1.2 1 0 0 1 1 1 1 YL1 nuclear protein TLP-20 PF06088.11 EEQ29338.1 - 0.0067 16.3 0.8 0.011 15.7 0.8 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.14 EEQ29338.1 - 0.61 8.3 6.2 0.83 7.9 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 EEQ29338.1 - 7.6 7.6 11.2 69 4.6 0.2 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat PIG-S PF10510.9 EEQ29339.1 - 7.5e-181 602.4 5.1 9.4e-181 602.1 5.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF1427 PF07235.11 EEQ29340.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) Haemadin PF09065.10 EEQ29340.1 - 2.7 7.9 9.6 1.9 8.3 5.8 2.7 2 0 0 2 2 2 0 Haemadin Sod_Fe_C PF02777.18 EEQ29341.1 - 1.2e-10 41.5 0.0 3.1e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Polyketide_cyc PF03364.20 EEQ29342.1 - 1.3e-19 70.6 0.0 2.4e-19 69.8 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport RdRP_2 PF00978.21 EEQ29342.1 - 0.042 12.8 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase JmjC PF02373.22 EEQ29344.1 - 4.7e-09 36.7 0.0 1.1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EEQ29344.1 - 2.9e-05 24.2 12.7 2.9e-05 24.2 12.7 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 ZZ PF00569.17 EEQ29344.1 - 9.4e-05 22.1 8.0 9.4e-05 22.1 8.0 2.7 2 1 0 2 2 2 1 Zinc finger, ZZ type Cupin_2 PF07883.11 EEQ29344.1 - 0.032 13.9 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 Cupin domain Baculo_IE-1 PF05290.11 EEQ29344.1 - 0.1 12.5 6.5 0.033 14.1 1.3 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Sulfatase PF00884.23 EEQ29345.1 - 3.5e-17 62.8 0.1 6.8e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EEQ29345.1 - 5.6e-05 22.9 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EEQ29345.1 - 0.027 13.1 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) PHO4 PF01384.20 EEQ29345.1 - 0.043 12.9 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family Lyase_1 PF00206.20 EEQ29347.1 - 1.1e-84 284.5 0.0 1.6e-84 283.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EEQ29347.1 - 5.4e-23 81.5 0.0 1.4e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal CSN7a_helixI PF18392.1 EEQ29347.1 - 0.068 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain CNOT1_HEAT PF16418.5 EEQ29347.1 - 0.095 12.8 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat AMP-binding PF00501.28 EEQ29348.1 - 3.3e-68 230.2 0.0 4.5e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ29348.1 - 4.9e-07 30.6 0.0 1e-06 29.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M36 PF02128.15 EEQ29349.1 - 5e-158 526.1 7.4 8.8e-158 525.3 7.4 1.4 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EEQ29349.1 - 5.3e-15 55.0 5.5 1.1e-14 54.0 4.0 2.2 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EEQ29349.1 - 0.0012 18.7 1.0 0.0027 17.6 0.0 2.2 3 0 0 3 3 3 1 Thermolysin metallopeptidase, alpha-helical domain Aminotran_1_2 PF00155.21 EEQ29350.1 - 4.8e-43 147.7 0.0 5.9e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EEQ29350.1 - 1.8e-08 34.0 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EEQ29350.1 - 1.5e-07 30.4 0.0 2.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EEQ29350.1 - 1.9e-07 30.4 0.0 2.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ29350.1 - 0.00032 20.1 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 EEQ29350.1 - 0.16 10.8 0.0 0.41 9.5 0.0 1.9 1 1 0 1 1 1 0 Allinase ABC2_membrane PF01061.24 EEQ29351.1 - 2.2e-37 128.5 21.1 3.8e-37 127.8 21.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EEQ29351.1 - 2.5e-27 96.1 0.0 4.8e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter EGF_2 PF07974.13 EEQ29351.1 - 2.9e-06 27.5 24.5 0.00013 22.2 12.6 3.1 2 0 0 2 2 2 2 EGF-like domain AAA_21 PF13304.6 EEQ29351.1 - 0.0019 18.1 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ29351.1 - 0.0071 16.1 0.2 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ29351.1 - 0.022 14.7 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EEQ29351.1 - 0.023 15.2 0.6 0.058 13.9 0.6 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EEQ29351.1 - 0.025 14.7 0.1 0.076 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EEQ29351.1 - 0.03 14.6 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEQ29351.1 - 0.044 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ29351.1 - 0.055 14.0 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ29351.1 - 0.069 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 EEQ29351.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 EEQ29351.1 - 0.19 11.9 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.24 EEQ29351.1 - 2.6 8.3 29.6 0.65 10.2 8.7 3.1 2 1 1 3 3 2 0 Laminin EGF domain hEGF PF12661.7 EEQ29351.1 - 7.3 7.4 20.1 0.46 11.2 6.9 3.2 3 0 0 3 3 2 0 Human growth factor-like EGF MFS_1 PF07690.16 EEQ29352.1 - 1.3e-18 67.0 42.8 1.2e-15 57.3 11.8 2.6 2 1 0 3 3 3 2 Major Facilitator Superfamily TerC PF03741.16 EEQ29352.1 - 0.073 12.7 0.1 0.073 12.7 0.1 2.8 2 2 0 2 2 2 0 Integral membrane protein TerC family Pkinase PF00069.25 EEQ29353.1 - 1.5e-13 50.7 0.0 4.1e-13 49.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29353.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Cornichon PF03311.14 EEQ29354.1 - 2.8e-50 169.7 13.6 3.3e-50 169.5 13.6 1.0 1 0 0 1 1 1 1 Cornichon protein PSP1 PF04468.12 EEQ29355.1 - 2e-28 98.5 2.9 3.6e-28 97.7 2.9 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region NifU PF01106.17 EEQ29356.1 - 5.9e-28 96.8 0.2 1.5e-27 95.5 0.1 1.7 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.11 EEQ29356.1 - 9.4e-27 92.9 0.0 3.2e-26 91.2 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal RasGEF PF00617.19 EEQ29357.1 - 5.2e-44 150.6 0.1 1.2e-43 149.4 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EEQ29357.1 - 1.8e-12 47.4 0.0 4e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 EEQ29357.1 - 0.027 14.1 0.0 0.1 12.2 0.0 1.9 1 1 0 1 1 1 0 Ras family AAA_16 PF13191.6 EEQ29357.1 - 0.044 14.1 0.0 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 EEQ29357.1 - 0.16 11.7 0.1 8.9 6.0 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CotJB PF12652.7 EEQ29357.1 - 0.31 11.3 3.4 3.2 8.0 0.2 2.6 2 0 0 2 2 2 0 CotJB protein Complex1_LYR_2 PF13233.6 EEQ29359.1 - 1.9e-21 76.6 0.4 2.3e-21 76.3 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like ABC_tran PF00005.27 EEQ29360.1 - 1.5e-47 161.6 0.0 8e-28 97.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ29360.1 - 1.3e-17 64.4 19.6 1.2e-12 48.1 5.4 4.3 2 1 2 4 4 4 2 ABC transporter transmembrane region AAA_23 PF13476.6 EEQ29360.1 - 2.8e-09 37.7 0.0 1.4e-05 25.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EEQ29360.1 - 1.4e-06 28.3 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EEQ29360.1 - 2e-06 27.4 0.1 0.013 15.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EEQ29360.1 - 3.4e-06 27.1 0.2 0.077 12.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EEQ29360.1 - 6e-06 26.7 0.1 0.1 12.9 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EEQ29360.1 - 2.5e-05 23.8 0.0 0.2 11.1 0.0 3.8 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EEQ29360.1 - 5.1e-05 23.3 0.1 0.01 15.9 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EEQ29360.1 - 0.00011 22.5 0.2 0.5 10.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 EEQ29360.1 - 0.0013 18.1 0.4 1 8.7 0.1 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 EEQ29360.1 - 0.0014 18.4 0.4 1.4 8.6 0.4 3.0 3 1 0 3 3 2 1 AAA domain MeaB PF03308.16 EEQ29360.1 - 0.0014 17.7 0.1 0.0023 16.9 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EEQ29360.1 - 0.0028 17.4 0.0 0.023 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EEQ29360.1 - 0.0049 16.0 0.0 0.76 8.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EEQ29360.1 - 0.0077 15.5 0.2 1.9 7.7 0.2 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 EEQ29360.1 - 0.0078 16.4 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 EEQ29360.1 - 0.0083 16.0 0.1 5.9 6.8 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 EEQ29360.1 - 0.01 15.6 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 EEQ29360.1 - 0.011 15.9 1.4 0.016 15.3 0.2 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 EEQ29360.1 - 0.012 16.0 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 EEQ29360.1 - 0.019 14.6 0.0 8.3 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EEQ29360.1 - 0.027 14.1 0.8 1.4 8.5 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EEQ29360.1 - 0.045 14.3 0.6 5.8 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EEQ29360.1 - 0.051 13.8 0.0 9.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EEQ29360.1 - 0.14 11.6 0.1 13 5.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EEQ29360.1 - 0.16 12.0 0.2 5.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 EEQ29360.1 - 0.16 11.9 1.6 15 5.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EEQ29360.1 - 0.16 12.4 0.1 7.6 7.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 EEQ29360.1 - 0.3 9.9 1.1 1.8 7.4 0.4 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Cyclin_N PF00134.23 EEQ29361.1 - 1.7e-05 24.6 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EEQ29361.1 - 0.0065 16.9 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin DUF1522 PF07482.11 EEQ29361.1 - 0.21 11.9 1.0 0.39 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) CCT_2 PF09425.10 EEQ29361.1 - 0.49 10.3 3.2 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Divergent CCT motif RAP1 PF07218.11 EEQ29361.1 - 2.3 6.4 3.3 3.2 5.9 3.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SBF PF01758.16 EEQ29362.1 - 4.2e-52 176.7 11.6 9.1e-52 175.6 11.6 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family FA_hydroxylase PF04116.13 EEQ29362.1 - 5.7 7.3 8.2 2.2 8.6 0.1 3.1 2 2 1 3 3 3 0 Fatty acid hydroxylase superfamily CDC45 PF02724.14 EEQ29364.1 - 0.54 8.5 4.0 0.72 8.1 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EEQ29364.1 - 0.71 7.9 8.5 1.2 7.1 8.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EEQ29364.1 - 3.1 5.9 8.7 4.9 5.2 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EEQ29364.1 - 9.5 5.4 9.1 14 4.8 9.1 1.2 1 0 0 1 1 1 0 NOA36 protein zn-ribbon_14 PF16503.5 EEQ29367.1 - 1.8e-19 68.9 5.1 1.8e-19 68.9 5.1 3.5 4 0 0 4 4 4 1 Zinc-ribbon ATP_bind_3 PF01171.20 EEQ29367.1 - 1e-18 67.8 0.0 1.6e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 EEQ29367.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 EEQ29367.1 - 0.45 10.7 6.4 2.6 8.3 0.6 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) RecR PF02132.15 EEQ29367.1 - 1.6 8.4 10.2 0.053 13.1 1.0 2.8 3 0 0 3 3 3 0 RecR protein Acetyltransf_8 PF13523.6 EEQ29368.1 - 5.8e-24 84.4 0.0 8.7e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 EEQ29369.1 - 3.6e-26 92.1 0.0 7.8e-26 91.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29369.1 - 9.7e-06 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ29369.1 - 0.0065 15.9 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1708 PF08101.11 EEQ29370.1 - 0.051 12.7 0.0 0.07 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) GNVR PF13807.6 EEQ29372.1 - 0.25 11.3 0.9 4.4 7.3 0.1 2.4 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase DUF4231 PF14015.6 EEQ29373.1 - 0.011 16.2 0.9 0.026 15.0 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Shisa PF13908.6 EEQ29373.1 - 0.52 10.5 2.7 0.63 10.3 2.1 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator zf-LITAF-like PF10601.9 EEQ29373.1 - 2.9 8.2 5.8 30 5.0 1.7 2.6 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain DUF1992 PF09350.10 EEQ29374.1 - 5.2e-21 74.6 0.2 1.8e-20 72.9 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) baeRF_family12 PF18856.1 EEQ29374.1 - 4 8.0 6.2 4.7 7.8 1.2 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 Hit1_C PF18268.1 EEQ29375.1 - 0.072 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Hit1 C-terminal p450 PF00067.22 EEQ29376.1 - 1.3e-50 172.5 0.0 2.1e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EEQ29377.1 - 9.6e-06 25.4 0.6 3.4e-05 23.6 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EEQ29377.1 - 0.015 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 F-box domain SRP40_C PF05022.12 EEQ29378.1 - 1.2e-18 67.8 0.0 4.4e-18 65.9 0.0 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain Troponin-I_N PF11636.8 EEQ29378.1 - 0.021 14.7 0.2 0.14 12.1 0.2 2.5 1 0 0 1 1 1 0 Troponin I residues 1-32 Sec3-PIP2_bind PF15277.6 EEQ29379.1 - 2.3e-29 101.4 0.1 4.3e-29 100.5 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.9 EEQ29379.1 - 3.5e-24 85.2 0.9 3.5e-24 85.2 0.9 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec3 DOCK_N PF16172.5 EEQ29380.1 - 5.8e-111 371.1 0.0 1.2e-110 370.0 0.0 1.6 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 EEQ29380.1 - 9.6e-41 139.7 0.0 4.6e-40 137.5 0.0 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 EEQ29380.1 - 5.6e-38 130.9 2.0 1.4e-37 129.5 2.0 1.6 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 EEQ29380.1 - 0.00014 21.4 0.0 0.00044 19.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEQ29380.1 - 0.00042 20.1 0.0 0.0059 16.4 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain Glyco_hydro_20 PF00728.22 EEQ29381.1 - 7.9e-101 338.0 0.1 9.8e-101 337.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EEQ29381.1 - 2e-28 99.7 0.1 1.2e-27 97.3 0.0 2.1 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EEQ29381.1 - 0.00054 20.7 0.0 0.00094 20.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 NmrA PF05368.13 EEQ29382.1 - 4.5e-17 62.4 0.0 1.5e-10 41.1 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EEQ29382.1 - 4e-07 30.1 0.0 8.4e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DUF4554 PF15091.6 EEQ29383.1 - 1.3 7.8 3.8 1.6 7.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Ribosomal_S8e PF01201.22 EEQ29384.1 - 1.9e-55 186.8 0.8 2.2e-55 186.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Ribonuclease_T2 PF00445.18 EEQ29385.1 - 2.8e-42 145.0 0.6 2.8e-42 145.0 0.6 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family GT-D PF08759.11 EEQ29385.1 - 0.011 15.4 0.3 0.016 14.9 0.3 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Na_sulph_symp PF00939.19 EEQ29386.1 - 1.2e-15 57.6 26.2 2e-15 56.8 26.2 1.4 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EEQ29386.1 - 2.1e-14 53.5 65.2 1.3e-12 47.6 35.2 2.0 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 EEQ29387.1 - 1.5e-41 143.6 0.4 2.4e-29 103.5 0.2 2.2 1 1 1 2 2 2 2 SPX domain Peptidase_S28 PF05577.12 EEQ29388.1 - 2e-53 181.7 0.2 1e-52 179.4 0.2 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EEQ29388.1 - 0.037 13.5 0.1 0.1 12.1 0.1 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_S7 PF00177.21 EEQ29389.1 - 8.5e-30 103.4 0.0 3.4e-29 101.4 0.0 1.9 3 0 0 3 3 3 1 Ribosomal protein S7p/S5e DUF1013 PF06242.11 EEQ29389.1 - 0.029 14.4 0.7 0.4 10.7 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1013) Na_Ca_ex PF01699.24 EEQ29390.1 - 1.8e-38 131.8 37.2 6.2e-22 78.2 15.0 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF5383 PF17355.2 EEQ29390.1 - 0.044 14.1 1.9 8 6.8 0.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5383) Cyt_bd_oxida_II PF02322.15 EEQ29390.1 - 0.049 13.0 19.1 0.38 10.1 0.3 2.5 2 1 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II Orf78 PF06024.12 EEQ29390.1 - 0.19 12.0 0.5 0.62 10.4 0.3 2.0 1 1 0 1 1 1 0 Orf78 (ac78) MFS_1 PF07690.16 EEQ29391.1 - 1.4e-27 96.5 31.0 1.4e-27 96.5 31.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DAO PF01266.24 EEQ29392.1 - 6.5e-31 108.2 0.2 1e-30 107.5 0.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EEQ29392.1 - 0.0007 18.8 0.0 0.96 8.5 0.0 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EEQ29392.1 - 0.00097 19.3 0.0 0.0029 17.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EEQ29392.1 - 0.028 14.4 0.1 0.69 9.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EEQ29392.1 - 0.036 13.2 0.7 0.12 11.4 0.7 1.8 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EEQ29392.1 - 0.044 13.0 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ29392.1 - 0.056 12.7 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EEQ29392.1 - 0.061 13.3 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.21 EEQ29392.1 - 0.063 12.6 0.1 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.19 EEQ29392.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thioredoxin PF00085.20 EEQ29393.1 - 1.3e-32 111.8 0.0 4.1e-24 84.6 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EEQ29393.1 - 1.7e-09 37.9 0.0 6.4e-05 22.9 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EEQ29393.1 - 0.00052 20.4 0.2 3.9 8.0 0.1 3.8 3 1 0 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 EEQ29393.1 - 0.0032 17.4 0.0 0.6 10.1 0.0 2.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 EEQ29393.1 - 0.011 16.1 0.0 0.82 10.0 0.0 2.9 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 EEQ29393.1 - 0.11 12.8 0.2 0.63 10.3 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like Presenilin PF01080.17 EEQ29393.1 - 0.27 9.9 0.6 0.47 9.2 0.6 1.3 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 EEQ29393.1 - 0.37 9.5 6.9 0.68 8.7 6.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ETC_C1_NDUFA5 PF04716.14 EEQ29394.1 - 8.1e-26 89.6 8.8 1.5e-25 88.7 0.2 2.8 3 0 0 3 3 3 2 ETC complex I subunit conserved region Coatomer_WDAD PF04053.14 EEQ29395.1 - 8.9e-172 572.1 0.0 1.8e-171 571.1 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EEQ29395.1 - 3.8e-38 128.8 4.7 2.9e-06 27.9 0.0 8.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29395.1 - 9.8e-06 25.8 0.1 3.8 7.9 0.0 5.8 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ29395.1 - 0.0012 17.6 1.5 0.13 10.9 0.0 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EEQ29395.1 - 0.085 12.9 0.0 13 5.9 0.0 3.4 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.25 EEQ29396.1 - 2.3e-70 237.0 0.0 2.9e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29396.1 - 3.7e-33 114.9 0.0 5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EEQ29396.1 - 5e-10 39.9 0.1 1.5e-09 38.4 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EEQ29396.1 - 3.3e-06 26.3 0.0 4.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EEQ29396.1 - 0.0038 16.6 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like C2 PF00168.30 EEQ29396.1 - 0.028 14.7 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 C2 domain Myb_DNA-binding PF00249.31 EEQ29397.1 - 6.5e-10 39.1 0.0 2.1e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EEQ29397.1 - 3.9e-09 36.2 5.1 6.9e-09 35.4 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 EEQ29397.1 - 4.2e-09 36.6 0.1 1.2e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain PG_binding_1 PF01471.18 EEQ29397.1 - 0.029 14.6 0.0 0.098 12.9 0.0 1.9 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF5112 PF17139.4 EEQ29397.1 - 0.069 12.6 0.7 0.11 12.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) TraB PF01963.17 EEQ29397.1 - 0.075 12.9 1.0 0.39 10.6 0.2 2.0 2 0 0 2 2 2 0 TraB family Pap_E4 PF02711.14 EEQ29397.1 - 0.18 12.8 1.6 0.93 10.5 1.6 2.2 1 0 0 1 1 1 0 E4 protein WD40 PF00400.32 EEQ29399.1 - 2.6e-14 53.4 11.1 0.00014 22.6 0.9 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Glycos_transf_4 PF00953.21 EEQ29400.1 - 7.8e-34 117.0 9.6 7.8e-34 117.0 9.6 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 DUF2070 PF09843.9 EEQ29400.1 - 7.7 4.7 11.5 3.7 5.7 9.0 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Aconitase PF00330.20 EEQ29401.1 - 1.2e-163 545.4 0.0 1.4e-163 545.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEQ29401.1 - 1.2e-39 135.6 0.0 2.3e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Pribosyltran PF00156.27 EEQ29402.1 - 1.8e-15 56.8 0.2 2.9e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MTHFR PF02219.17 EEQ29403.1 - 1.8e-116 388.5 0.0 2.5e-116 388.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.11 EEQ29403.1 - 0.2 11.6 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Galanin PF01296.18 EEQ29404.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Galanin DUF2418 PF10332.9 EEQ29405.1 - 2.8e-34 117.5 0.2 5.9e-34 116.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Disaggr_assoc PF08480.10 EEQ29405.1 - 0.045 13.6 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 Disaggregatase related Adeno_E3_CR2 PF02439.15 EEQ29405.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ATP-synt_F PF01990.17 EEQ29406.1 - 5e-33 113.3 0.0 5.7e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.15 EEQ29407.1 - 1.6e-26 93.3 0.4 2e-26 93.0 0.4 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EEQ29407.1 - 0.00019 21.8 0.0 0.00059 20.2 0.0 1.7 1 1 0 1 1 1 1 ML-like domain Glyco_hydro_61 PF03443.14 EEQ29407.1 - 0.041 13.8 0.0 0.094 12.6 0.0 1.6 1 1 1 2 2 2 0 Glycosyl hydrolase family 61 NOG1_N PF17835.1 EEQ29408.1 - 7.2e-48 162.6 1.3 9.4e-48 162.2 0.1 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EEQ29408.1 - 2.6e-28 97.8 1.8 5.9e-28 96.6 1.8 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EEQ29408.1 - 6.4e-26 89.9 0.4 1.4e-25 88.8 0.4 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EEQ29408.1 - 1.6e-15 57.2 0.0 4.1e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ29408.1 - 9.2e-08 31.8 0.0 2.7e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEQ29408.1 - 0.00018 21.5 0.5 0.039 13.8 0.0 3.1 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 EEQ29408.1 - 0.0018 18.3 0.0 0.55 10.3 0.0 2.8 1 1 1 2 2 2 1 Dynamin family Gtr1_RagA PF04670.12 EEQ29408.1 - 0.011 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EEQ29408.1 - 0.019 15.3 1.8 0.17 12.3 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 EEQ29408.1 - 0.17 12.1 0.0 1 9.6 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Acetyltransf_10 PF13673.7 EEQ29409.1 - 2e-11 43.9 0.0 3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ29409.1 - 1.8e-10 41.0 0.0 3.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ29409.1 - 3e-08 34.0 0.0 5.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ29409.1 - 2.8e-05 24.0 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF2457 PF10446.9 EEQ29409.1 - 0.03 13.5 2.1 0.036 13.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MOZ_SAS PF01853.18 EEQ29409.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Pox_Ag35 PF03286.14 EEQ29409.1 - 0.25 11.1 1.3 0.43 10.4 1.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 EEQ29409.1 - 4.9 7.6 11.6 10 6.5 11.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Asp_protease PF09668.10 EEQ29410.1 - 3.4e-61 204.5 0.2 5e-61 204.0 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EEQ29410.1 - 8.2e-23 80.8 0.0 1.7e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EEQ29410.1 - 3.3e-11 43.7 0.0 1.6e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 EEQ29410.1 - 1.4e-08 34.3 0.0 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EEQ29410.1 - 4.6e-07 29.6 0.0 9.7e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EEQ29410.1 - 0.00052 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP_2 PF08284.11 EEQ29410.1 - 0.0048 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 EEQ29410.1 - 0.0051 16.6 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UN_NPL4 PF11543.8 EEQ29410.1 - 0.0082 16.6 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 RVP PF00077.20 EEQ29410.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease NAD_binding_7 PF13241.6 EEQ29410.1 - 0.027 14.9 0.1 0.23 11.9 0.0 2.3 3 0 0 3 3 3 0 Putative NAD(P)-binding Ubiquitin_4 PF18036.1 EEQ29410.1 - 0.19 11.8 0.1 3.9 7.6 0.0 2.6 2 1 1 3 3 3 0 Ubiquitin-like domain Fungal_trans_2 PF11951.8 EEQ29411.1 - 3.5e-20 72.2 0.2 6e-15 54.9 1.1 3.1 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ29411.1 - 5.5e-07 29.6 11.9 9.2e-07 28.9 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC154 PF15450.6 EEQ29412.1 - 0.31 9.6 0.0 0.39 9.2 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 GalP_UDP_transf PF01087.22 EEQ29413.1 - 1.4e-69 234.2 0.1 1.7e-68 230.7 0.1 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EEQ29413.1 - 3e-58 196.2 0.1 8.2e-58 194.8 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 EEQ29413.1 - 0.0014 17.5 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4921) WG_beta_rep PF14903.6 EEQ29413.1 - 0.18 12.1 0.1 0.5 10.7 0.1 1.8 1 0 0 1 1 1 0 WG containing repeat Erg28 PF03694.13 EEQ29414.1 - 8.7e-43 145.2 3.8 1.1e-42 144.9 3.8 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.25 EEQ29415.1 - 6.3e-41 140.0 0.0 8.4e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ29415.1 - 1e-23 84.1 0.0 1.4e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ29415.1 - 8.3e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EEQ29415.1 - 0.0022 17.2 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EEQ29415.1 - 0.0057 16.1 0.0 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EEQ29415.1 - 0.053 13.0 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 EEQ29416.1 - 9.1e-11 41.9 0.0 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ29416.1 - 7.6e-10 39.4 0.0 2.7e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ29416.1 - 2.5e-08 34.5 0.0 6.2e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ29416.1 - 1.3e-05 25.0 0.0 6e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ29416.1 - 3.2e-05 24.6 0.0 9.8e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EEQ29416.1 - 0.00052 19.4 0.0 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 EEQ29416.1 - 0.00061 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 EEQ29416.1 - 0.01 16.0 0.1 0.033 14.3 0.0 1.8 2 1 0 3 3 3 0 FtsJ-like methyltransferase DUF1923 PF09083.10 EEQ29417.1 - 0.17 11.6 1.9 2.4 7.9 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1923) KH_8 PF17903.1 EEQ29418.1 - 2.2e-30 104.6 0.0 5.7e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain GCP_N_terminal PF17681.1 EEQ29419.1 - 1e-64 219.1 0.0 1.7e-64 218.4 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EEQ29419.1 - 5e-60 203.6 3.4 5e-60 203.6 3.4 1.4 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Proteasome PF00227.26 EEQ29420.1 - 2.4e-53 180.5 0.1 3.3e-53 180.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEQ29420.1 - 1.5e-12 47.0 0.2 3.7e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_8 PF05148.15 EEQ29421.1 - 4.5e-59 199.9 0.3 9e-56 189.2 0.0 2.8 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EEQ29421.1 - 2.7e-06 28.0 0.0 1.3e-05 25.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ29421.1 - 2.9e-05 24.7 0.0 0.0021 18.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ29421.1 - 0.031 14.1 0.0 1.2 8.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EEQ29421.1 - 0.13 12.3 3.7 0.14 12.2 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Ctr PF04145.15 EEQ29421.1 - 3.8 8.1 6.2 7.7 7.1 0.0 2.6 2 1 0 2 2 2 0 Ctr copper transporter family DUF908 PF06012.12 EEQ29421.1 - 7.9 5.8 10.8 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Abhydrolase_6 PF12697.7 EEQ29423.1 - 1.5e-17 65.0 0.1 2e-17 64.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ29423.1 - 7.8e-12 45.0 0.0 1.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ29423.1 - 8.7e-12 45.2 0.8 5.1e-10 39.4 0.8 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EEQ29423.1 - 0.00019 21.6 0.1 0.00028 21.1 0.1 1.4 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EEQ29423.1 - 0.00087 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S28 PF05577.12 EEQ29423.1 - 0.015 14.1 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_8 PF06259.12 EEQ29423.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase F-box-like PF12937.7 EEQ29424.1 - 1e-05 25.3 1.1 2.9e-05 23.9 1.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EEQ29424.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 F-box NAD_binding_2 PF03446.15 EEQ29425.1 - 1.2e-32 113.3 2.6 1.2e-32 113.3 0.1 2.2 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EEQ29425.1 - 5.5e-13 49.3 0.3 2.7e-12 47.1 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EEQ29425.1 - 1.1e-11 45.0 0.1 2.5e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 EEQ29425.1 - 2.1e-10 40.9 2.8 7.4e-10 39.1 2.8 1.9 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.12 EEQ29425.1 - 0.00011 21.9 0.1 0.00021 20.9 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 EEQ29425.1 - 0.013 15.8 0.0 0.031 14.5 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EEQ29425.1 - 0.013 15.7 0.1 0.031 14.5 0.1 1.7 1 1 0 1 1 1 0 TrkA-N domain OCD_Mu_crystall PF02423.15 EEQ29425.1 - 0.017 14.1 0.1 0.029 13.3 0.1 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_10 PF13460.6 EEQ29425.1 - 0.019 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding GFO_IDH_MocA PF01408.22 EEQ29425.1 - 0.04 14.8 0.0 0.11 13.3 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EEQ29425.1 - 0.11 13.2 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Glyco_hydro_72 PF03198.14 EEQ29426.1 - 1.1e-119 399.4 2.6 1.5e-119 398.9 2.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EEQ29426.1 - 1.1e-22 80.5 1.1 3e-22 79.1 1.1 1.8 1 0 0 1 1 1 1 X8 domain TraW_N PF12477.8 EEQ29426.1 - 0.093 12.7 3.8 0.17 11.9 3.8 1.5 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Cellulase PF00150.18 EEQ29426.1 - 0.1 12.0 0.6 6 6.2 0.0 2.4 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) BAR_2 PF10455.9 EEQ29428.1 - 1.6e-61 207.9 0.2 2.5e-61 207.3 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EEQ29428.1 - 3.5e-20 72.7 5.8 9.6e-19 68.0 5.8 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EEQ29428.1 - 0.012 15.4 0.9 0.07 12.8 0.1 2.2 2 0 0 2 2 2 0 BAR domain of APPL family ApoLp-III PF07464.11 EEQ29428.1 - 0.027 14.6 2.7 0.92 9.6 0.1 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TetR_C_24 PF17932.1 EEQ29428.1 - 0.057 13.7 0.2 0.21 11.9 0.1 2.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SRP_TPR_like PF17004.5 EEQ29428.1 - 0.071 13.1 0.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative TPR-like repeat TACC_C PF05010.14 EEQ29428.1 - 0.093 12.5 2.1 3.5 7.4 0.2 2.5 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SPATA19 PF15212.6 EEQ29428.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial GAS PF13851.6 EEQ29428.1 - 0.17 11.2 3.0 8.4 5.7 0.8 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Dabb PF07876.12 EEQ29430.1 - 3.8e-16 59.5 0.0 4.1e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4123 PF13503.6 EEQ29430.1 - 0.19 12.2 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) BTRD1 PF17660.1 EEQ29430.1 - 0.19 11.6 0.1 0.29 11.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 Arv1 PF04161.13 EEQ29431.1 - 8.9e-61 205.7 0.0 1.8e-51 175.3 0.0 2.3 2 0 0 2 2 2 2 Arv1-like family NAT PF04768.13 EEQ29432.1 - 8.3e-51 172.0 0.0 2.5e-50 170.5 0.0 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase DUF2781 PF10914.8 EEQ29433.1 - 2.2e-35 122.2 12.7 2.7e-35 121.9 12.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Nucleoporin_N PF08801.11 EEQ29434.1 - 1.4e-85 287.7 0.0 2.1e-85 287.1 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EEQ29434.1 - 1.4e-44 152.8 2.6 9.8e-44 150.1 1.0 2.0 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Fungal_lectin PF07938.12 EEQ29434.1 - 0.069 12.5 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 Fungal fucose-specific lectin YqeY PF09424.10 EEQ29435.1 - 5.1e-21 75.2 2.7 6e-21 75.0 2.7 1.0 1 0 0 1 1 1 1 Yqey-like protein Rot1 PF10681.9 EEQ29436.1 - 1.2e-95 318.9 0.1 1.4e-95 318.7 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF3104 PF11302.8 EEQ29436.1 - 0.17 11.6 0.2 0.34 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) 5-FTHF_cyc-lig PF01812.20 EEQ29437.1 - 1.4e-30 106.5 0.1 4.4e-30 104.9 0.1 1.7 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.22 EEQ29438.1 - 6.9e-13 48.1 0.1 8e-13 47.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EEQ29438.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Xpo1 PF08389.12 EEQ29439.1 - 3.7e-28 98.5 0.1 7.3e-27 94.3 0.1 3.0 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 EEQ29439.1 - 0.0089 16.4 0.0 0.073 13.5 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 EEQ29439.1 - 0.013 16.0 0.0 0.22 12.1 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 EEQ29439.1 - 0.052 13.8 0.0 31 5.2 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat Glyco_transf_90 PF05686.12 EEQ29440.1 - 8.3e-15 54.6 0.2 3.8e-12 45.8 0.4 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Fungal_trans PF04082.18 EEQ29441.1 - 4.6e-63 212.7 0.3 7e-63 212.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EEQ29441.1 - 0.0028 18.0 14.8 0.011 16.1 3.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EEQ29441.1 - 0.039 14.2 1.2 0.12 12.7 1.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon EF-hand_7 PF13499.6 EEQ29443.1 - 8.5e-08 32.5 0.0 1.9e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 EEQ29443.1 - 4.6e-06 26.9 0.0 2.7e-05 24.4 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EEQ29443.1 - 8.6e-05 21.8 0.0 0.052 13.1 0.0 2.8 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EEQ29443.1 - 8.8e-05 22.1 0.0 0.0099 15.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EEQ29443.1 - 0.00011 21.9 0.0 0.0039 17.0 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair DUF4637 PF15470.6 EEQ29444.1 - 0.2 11.3 6.5 0.072 12.8 3.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Eapp_C PF10238.9 EEQ29444.1 - 0.49 10.5 3.4 0.95 9.5 0.4 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Zn_ribbon_SprT PF17283.2 EEQ29444.1 - 0.69 9.9 4.4 9.8 6.2 0.1 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain E7 PF00527.18 EEQ29444.1 - 3.4 7.9 8.6 4.3 7.6 5.1 2.5 2 1 0 2 2 2 0 E7 protein, Early protein Spt5_N PF11942.8 EEQ29444.1 - 5.1 8.1 12.8 0.45 11.5 7.6 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Peptidase_M3 PF01432.20 EEQ29445.1 - 1.6e-166 555.1 0.2 2.2e-166 554.7 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF1064 PF06356.11 EEQ29445.1 - 0.24 11.7 1.7 0.47 10.8 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1064) FA_desaturase PF00487.24 EEQ29446.1 - 8.2e-19 68.4 11.2 8.2e-19 68.4 11.2 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EEQ29446.1 - 3.6e-17 62.3 0.2 1e-16 60.8 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF1189 PF06691.11 EEQ29446.1 - 0.21 11.1 0.2 0.48 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) Rad51 PF08423.11 EEQ29448.1 - 0.0043 16.4 0.0 0.017 14.4 0.0 1.9 1 1 0 1 1 1 1 Rad51 Amidase PF01425.21 EEQ29449.1 - 2.2e-72 244.5 0.0 2.7e-71 240.9 0.0 2.0 1 1 0 1 1 1 1 Amidase Penicillinase_R PF03965.16 EEQ29449.1 - 0.21 12.0 0.0 0.37 11.2 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor HalX PF08663.10 EEQ29449.1 - 0.46 10.8 1.6 1.1 9.7 1.4 1.7 1 1 1 2 2 2 0 HalX domain MOSC PF03473.17 EEQ29450.1 - 2.2e-21 76.2 0.1 3.8e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EEQ29450.1 - 7.9e-11 41.9 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain APH PF01636.23 EEQ29453.1 - 1.9e-06 28.0 0.4 3.9e-06 27.0 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family SAP30_Sin3_bdg PF13867.6 EEQ29454.1 - 2.5e-09 37.3 0.1 6.9e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 BRO1 PF03097.18 EEQ29455.1 - 5.9e-124 413.8 0.4 5.9e-124 413.8 0.4 1.9 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EEQ29455.1 - 2e-80 270.3 14.6 3.7e-80 269.4 14.6 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF1672 PF07901.11 EEQ29455.1 - 0.14 11.5 4.3 0.052 12.9 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1672) DnaJ_C PF01556.18 EEQ29456.1 - 1.4e-35 122.6 0.0 1.9e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEQ29456.1 - 2.6e-23 81.9 0.9 6e-23 80.8 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EEQ29456.1 - 1.5e-10 41.3 20.2 3.6e-10 40.0 20.2 1.7 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EEQ29456.1 - 0.22 11.6 8.0 0.13 12.3 1.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EEQ29456.1 - 2.3 8.2 19.0 0.15 12.1 4.6 2.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Lon_C PF05362.13 EEQ29457.1 - 1.5e-62 210.8 0.0 3.2e-62 209.7 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EEQ29457.1 - 1.3e-35 123.2 0.1 3.2e-35 121.9 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EEQ29457.1 - 4.3e-22 79.0 0.0 1e-21 77.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEQ29457.1 - 1.1e-06 28.6 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ29457.1 - 2e-06 28.0 0.0 5.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 EEQ29457.1 - 6.2e-06 26.1 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 EEQ29457.1 - 3.1e-05 23.0 0.1 0.0001 21.4 0.0 1.8 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.6 EEQ29457.1 - 3.4e-05 24.1 0.1 0.0005 20.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EEQ29457.1 - 5.9e-05 22.9 0.1 0.00062 19.6 0.0 2.7 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEQ29457.1 - 0.00025 21.5 1.2 0.0016 18.8 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EEQ29457.1 - 0.0093 16.5 1.0 0.076 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EEQ29457.1 - 0.011 15.6 0.4 1.5 8.7 0.0 3.3 2 1 1 3 3 3 0 NTPase AAA_14 PF13173.6 EEQ29457.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EEQ29457.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EEQ29457.1 - 0.041 13.8 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 EEQ29457.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEQ29457.1 - 0.048 14.0 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase F-box-like_2 PF13013.6 EEQ29457.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain AAA_7 PF12775.7 EEQ29457.1 - 0.14 11.7 0.6 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF445 PF04286.12 EEQ29457.1 - 0.53 10.0 6.4 0.53 10.0 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) ABC_tran PF00005.27 EEQ29457.1 - 1.2 9.6 4.9 0.84 10.2 0.0 2.8 3 0 0 3 3 3 0 ABC transporter Pkinase PF00069.25 EEQ29460.1 - 8.4e-11 41.7 0.0 1.5e-09 37.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29460.1 - 2e-09 37.1 0.0 2.3e-08 33.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Mob1_phocein PF03637.17 EEQ29461.1 - 3.6e-23 82.4 0.1 1.6e-22 80.4 0.0 1.9 2 0 0 2 2 2 1 Mob1/phocein family CxC6 PF18721.1 EEQ29461.1 - 0.59 10.4 5.1 1.3 9.4 5.1 1.5 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 EEQ29462.1 - 5e-48 163.0 0.7 6.8e-48 162.6 0.7 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EEQ29462.1 - 1.4e-06 28.2 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EEQ29462.1 - 1.1e-05 25.5 0.7 0.088 12.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 EEQ29462.1 - 3.6e-05 23.7 0.1 8.8e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EEQ29462.1 - 0.00034 21.2 0.2 0.04 14.5 0.1 2.7 2 1 1 3 3 3 1 AAA domain TsaE PF02367.17 EEQ29462.1 - 0.00079 19.4 0.0 0.014 15.4 0.0 2.6 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EEQ29462.1 - 0.0033 17.2 0.0 0.41 10.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EEQ29462.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase CDCA PF18484.1 EEQ29462.1 - 0.0063 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Cadmium carbonic anhydrase repeat ABC_tran PF00005.27 EEQ29462.1 - 0.021 15.3 0.0 0.062 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 EEQ29462.1 - 0.025 13.6 0.3 1.1 8.2 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EEQ29462.1 - 0.03 14.7 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EEQ29462.1 - 0.045 14.0 0.2 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EEQ29462.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EEQ29462.1 - 0.19 12.0 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain HAUS6_N PF14661.6 EEQ29463.1 - 2e-43 148.6 0.1 3.5e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.6 EEQ29464.1 - 2.7e-49 167.3 0.1 3.2e-49 167.0 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EEQ29464.1 - 8.6e-13 48.4 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EEQ29464.1 - 0.005 17.1 0.0 0.0094 16.2 0.0 1.5 1 0 0 1 1 1 1 HD domain Rad4 PF03835.15 EEQ29465.1 - 6.3e-29 100.6 0.1 1.5e-28 99.3 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EEQ29465.1 - 1.2e-28 99.3 0.2 2.5e-28 98.3 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 EEQ29465.1 - 1.2e-16 61.4 1.2 2.5e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 EEQ29465.1 - 3.2e-14 52.5 0.1 7.6e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 EEQ29465.1 - 0.0054 17.2 0.0 0.022 15.2 0.0 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF1774 PF08611.10 EEQ29466.1 - 1.8e-21 76.2 8.1 1.8e-21 76.2 8.1 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Peptidase_M28 PF04389.17 EEQ29467.1 - 6.6e-32 110.8 0.0 1e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EEQ29467.1 - 0.00042 20.1 0.1 0.00065 19.5 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EEQ29467.1 - 0.0016 18.0 0.2 0.13 11.8 0.0 2.2 2 0 0 2 2 2 2 Nicastrin R3H-assoc PF13902.6 EEQ29468.1 - 8.7e-28 97.4 14.8 1.5e-27 96.6 14.8 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 EEQ29468.1 - 0.0055 16.7 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 R3H domain PIN_8 PF18476.1 EEQ29468.1 - 0.082 12.8 6.9 0.12 12.2 6.9 1.1 1 0 0 1 1 1 0 PIN like domain DUF1945 PF09178.10 EEQ29468.1 - 0.16 12.2 0.0 8.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) Hist_deacetyl PF00850.19 EEQ29469.1 - 8.2e-51 173.3 0.0 1.9e-50 172.1 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylase domain zf-AN1 PF01428.16 EEQ29470.1 - 2.1e-24 85.4 25.8 2.1e-12 47.0 9.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EEQ29470.1 - 0.0025 18.0 5.5 0.0025 18.0 5.5 3.2 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EEQ29470.1 - 0.0033 17.7 12.2 0.038 14.4 3.1 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain Zn-ribbon_8 PF09723.10 EEQ29470.1 - 5.6 7.2 14.8 0.42 10.8 2.5 2.8 3 0 0 3 3 3 0 Zinc ribbon domain C1_4 PF07975.12 EEQ29470.1 - 7.8 6.8 18.8 2.8 8.2 7.3 3.0 2 2 0 2 2 2 0 TFIIH C1-like domain Thymidylat_synt PF00303.19 EEQ29471.1 - 5.3e-104 347.1 0.0 6e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Dickkopf_N PF04706.12 EEQ29472.1 - 0.003 18.0 62.9 0.05 14.1 12.5 4.3 4 0 0 4 4 4 4 Dickkopf N-terminal cysteine-rich region Toxin_27 PF08099.11 EEQ29472.1 - 0.007 16.5 7.5 0.007 16.5 7.5 6.3 6 2 0 6 6 6 1 Scorpion calcine family Conotoxin_I2 PF17557.2 EEQ29472.1 - 0.007 16.5 15.8 0.015 15.4 4.3 7.5 5 2 2 7 7 7 2 I2-superfamily conotoxins EB PF01683.18 EEQ29472.1 - 0.027 14.7 1.9 0.027 14.7 1.9 6.8 1 1 6 7 7 7 0 EB module Toxin_29 PF08116.11 EEQ29472.1 - 0.048 13.7 4.4 0.048 13.7 4.4 6.3 6 2 1 7 7 7 0 PhTx neurotoxin family TGT PF01702.18 EEQ29473.1 - 2.2e-145 484.2 0.0 2.6e-145 484.0 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Fungal_trans PF04082.18 EEQ29475.1 - 2.2e-17 63.0 0.3 8.1e-17 61.1 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ29475.1 - 4.6e-10 39.5 10.4 1e-09 38.3 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KIAA1430 PF13879.6 EEQ29475.1 - 0.22 12.3 2.1 0.52 11.1 2.1 1.6 1 0 0 1 1 1 0 KIAA1430 homologue DND1_DSRM PF14709.7 EEQ29476.1 - 0.0022 18.2 0.1 0.0067 16.7 0.1 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 APH PF01636.23 EEQ29480.1 - 4.6e-10 39.8 0.0 2.7e-05 24.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Glyco_hydro_18 PF00704.28 EEQ29481.1 - 6.7e-58 196.9 2.4 2.8e-28 99.5 0.1 2.9 2 1 1 3 3 3 2 Glycosyl hydrolases family 18 Aspzincin_M35 PF14521.6 EEQ29482.1 - 4e-06 27.4 0.2 1.1e-05 26.0 0.2 1.7 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Ala_racemase_N PF01168.20 EEQ29483.1 - 1.9e-16 60.4 0.0 2.6e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ten_N PF06484.12 EEQ29483.1 - 0.045 13.6 1.0 0.06 13.2 1.0 1.2 1 0 0 1 1 1 0 Teneurin Intracellular Region Adaptin_N PF01602.20 EEQ29484.1 - 2.5e-123 412.4 4.4 3.4e-123 412.0 4.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EEQ29484.1 - 2.7e-41 140.3 0.0 5.9e-41 139.2 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EEQ29484.1 - 9.7e-17 61.3 0.0 3e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain RIX1 PF08167.12 EEQ29484.1 - 0.029 14.1 0.0 1.8 8.2 0.0 2.8 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 EEQ29484.1 - 0.14 12.4 0.3 0.94 9.7 0.1 2.6 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 efThoc1 PF11957.8 EEQ29488.1 - 3.3e-152 507.6 2.7 4.3e-152 507.2 2.7 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Aquarius_N PF16399.5 EEQ29489.1 - 0 1079.2 0.4 0 1078.9 0.4 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EEQ29489.1 - 7.9e-26 90.9 0.0 1.6e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEQ29489.1 - 9.1e-22 78.1 0.0 6.5e-21 75.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEQ29489.1 - 2.9e-07 30.4 0.0 7.5e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEQ29489.1 - 7.8e-07 29.5 0.0 2.2e-06 28.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 EEQ29489.1 - 7.6e-06 26.0 0.0 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EEQ29489.1 - 0.00014 21.7 0.1 0.12 12.1 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EEQ29489.1 - 0.0011 19.4 0.2 0.0055 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain UvrD-helicase PF00580.21 EEQ29489.1 - 0.0018 17.8 0.1 0.0057 16.2 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DnaB_C PF03796.15 EEQ29489.1 - 0.0055 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 EEQ29489.1 - 0.007 16.8 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEQ29489.1 - 0.016 15.2 0.0 0.32 11.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 EEQ29489.1 - 0.027 13.3 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF2075 PF09848.9 EEQ29489.1 - 0.028 13.7 0.7 0.075 12.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 EEQ29489.1 - 0.032 13.4 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain UvrD_C_2 PF13538.6 EEQ29489.1 - 0.033 14.0 0.2 0.07 13.0 0.2 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.29 EEQ29489.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATPase_2 PF01637.18 EEQ29489.1 - 0.059 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EEQ29489.1 - 0.061 13.6 2.5 0.21 11.9 0.2 2.7 2 1 1 3 3 2 0 AAA domain PIF1 PF05970.14 EEQ29489.1 - 0.075 12.2 0.0 6 5.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_7 PF12775.7 EEQ29489.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region 4HBT PF03061.22 EEQ29490.1 - 1.8e-14 53.8 0.1 2.7e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Transp_cyt_pur PF02133.15 EEQ29491.1 - 2.3e-91 306.8 35.6 2.3e-91 306.8 35.6 1.4 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Tfb2 PF03849.14 EEQ29492.1 - 1.1e-136 455.5 0.0 1.7e-136 454.9 0.0 1.3 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EEQ29492.1 - 6e-24 84.3 0.6 1.3e-23 83.2 0.6 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EEQ29492.1 - 7.4e-05 22.9 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TRAM PF01938.20 EEQ29493.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TRAM domain PhzC-PhzF PF02567.16 EEQ29494.1 - 3.2e-40 138.4 0.2 9.3e-40 136.9 0.2 1.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein TIMELESS PF04821.14 EEQ29495.1 - 1e-85 287.4 0.0 3.4e-85 285.6 0.0 2.0 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 EEQ29495.1 - 1.4e-44 153.2 23.5 2.8e-43 148.9 12.1 4.1 2 1 0 2 2 2 1 Timeless protein C terminal region Keratin_assoc PF09775.9 EEQ29495.1 - 0.19 11.4 0.4 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 3HCDH_N PF02737.18 EEQ29496.1 - 1.3e-51 175.1 0.7 1.7e-51 174.7 0.7 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EEQ29496.1 - 3.9e-34 117.2 0.0 8.9e-34 116.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EEQ29496.1 - 0.0009 19.4 0.7 0.0021 18.2 0.2 1.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EEQ29496.1 - 0.00096 18.8 0.1 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EEQ29496.1 - 0.0039 17.5 0.1 0.0062 16.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 EEQ29496.1 - 0.015 14.6 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ29496.1 - 0.028 14.0 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 EEQ29496.1 - 0.037 13.6 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EEQ29496.1 - 0.061 12.7 0.9 0.67 9.3 0.9 2.1 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IBR PF01485.21 EEQ29497.1 - 3.1e-06 27.3 10.1 3.1e-06 27.3 10.1 3.3 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EEQ29497.1 - 4.9 7.6 19.0 4.8 7.6 5.0 2.9 2 0 0 2 2 2 0 Ring finger domain Actin PF00022.19 EEQ29500.1 - 3.8e-103 345.2 0.0 3.3e-102 342.1 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEQ29500.1 - 0.18 10.6 0.0 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein ADH_N PF08240.12 EEQ29501.1 - 1.2e-28 99.2 1.0 1.9e-28 98.5 1.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ29501.1 - 1.3e-23 83.4 0.0 2.2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EEQ29501.1 - 0.028 13.9 0.2 0.053 13.0 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ29501.1 - 0.03 15.4 0.0 0.049 14.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EEQ29501.1 - 0.037 13.3 0.2 0.056 12.7 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EEQ29501.1 - 0.063 12.6 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GCIP PF13324.6 EEQ29502.1 - 5.3e-27 95.1 2.5 8.1e-27 94.5 2.5 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.13 EEQ29502.1 - 0.0014 18.5 2.4 0.0025 17.7 2.4 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region PMC2NT PF08066.12 EEQ29502.1 - 0.06 14.0 0.0 18 6.1 0.0 3.3 2 1 1 3 3 3 0 PMC2NT (NUC016) domain LRR_8 PF13855.6 EEQ29503.1 - 2.7e-29 100.7 39.3 8.9e-09 35.0 3.2 8.7 7 2 1 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 EEQ29503.1 - 1.3e-25 89.0 49.7 5.1e-05 23.6 1.2 10.4 6 3 3 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EEQ29503.1 - 4.7e-06 26.4 30.5 3.2 8.7 0.0 12.4 12 1 0 12 12 12 1 Leucine Rich Repeat LRR_9 PF14580.6 EEQ29503.1 - 0.0067 16.0 21.0 0.91 9.0 0.6 5.0 2 2 2 5 5 5 5 Leucine-rich repeat CDC27 PF09507.10 EEQ29503.1 - 7.6 5.8 14.1 15 4.8 14.1 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TMF_TATA_bd PF12325.8 EEQ29504.1 - 0.048 13.9 9.9 0.099 12.9 9.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GrpE PF01025.19 EEQ29504.1 - 0.058 13.1 5.9 2.1 8.0 1.4 2.3 2 0 0 2 2 2 0 GrpE Mto2_bdg PF12808.7 EEQ29504.1 - 0.17 12.2 6.8 0.096 13.0 1.7 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4407 PF14362.6 EEQ29504.1 - 2.6 7.3 6.8 4.6 6.5 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L13e PF01294.18 EEQ29505.1 - 1.3e-74 249.9 3.0 1.9e-74 249.4 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e BAF1_ABF1 PF04684.13 EEQ29505.1 - 0.12 11.5 0.9 0.15 11.1 0.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4635 PF15466.6 EEQ29506.1 - 2.1 7.9 4.5 3.6 7.1 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Oxidored-like PF09791.9 EEQ29507.1 - 3.9e-24 84.0 4.9 1.4e-23 82.3 4.9 2.0 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 EEQ29507.1 - 1.4 9.0 8.1 0.17 11.9 3.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5522) KAP PF05804.12 EEQ29508.1 - 0.00023 19.5 0.0 0.0014 16.9 0.0 1.9 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) F-box-like PF12937.7 EEQ29509.1 - 0.00018 21.3 2.1 0.00048 20.0 2.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ29509.1 - 0.17 11.8 1.3 0.52 10.3 1.3 1.9 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 EEQ29509.1 - 0.23 11.4 2.1 0.27 11.1 0.2 2.0 2 0 0 2 2 2 0 F-box Fungal_lectin_2 PF18647.1 EEQ29511.1 - 0.02 15.3 5.9 0.047 14.2 2.2 2.6 2 0 0 2 2 2 0 Alpha-galactosyl-binding fungal lectin DPM3 PF08285.11 EEQ29512.1 - 1.1e-32 112.1 0.3 1.2e-32 111.9 0.3 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Yip1 PF04893.17 EEQ29512.1 - 0.083 12.6 2.2 0.11 12.2 2.2 1.1 1 0 0 1 1 1 0 Yip1 domain Pribosyltran PF00156.27 EEQ29513.1 - 5.9e-06 25.9 0.0 9.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HSF_DNA-bind PF00447.17 EEQ29515.1 - 9.1e-10 39.0 0.1 8.1e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding HTH_29 PF13551.6 EEQ29515.1 - 0.085 12.9 0.8 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn helix GCD14_N PF14801.6 EEQ29515.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term DUF3245 PF11595.8 EEQ29516.1 - 4e-41 141.0 7.3 5.8e-41 140.4 7.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) ATP-grasp_2 PF08442.10 EEQ29517.1 - 5.9e-77 257.8 0.2 9.8e-77 257.1 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EEQ29517.1 - 6e-25 87.8 0.6 1.9e-24 86.2 0.3 1.9 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 EEQ29517.1 - 7.6e-09 35.4 0.3 1.6e-08 34.3 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EEQ29517.1 - 0.00025 20.9 1.2 0.051 13.3 0.1 2.6 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 EEQ29517.1 - 0.0088 15.8 0.3 1.4 8.7 0.1 2.6 1 1 1 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain VID27_N PF17748.1 EEQ29517.1 - 0.15 11.9 0.9 0.27 11.1 0.9 1.4 1 0 0 1 1 1 0 VID27 N-terminal region adh_short PF00106.25 EEQ29518.1 - 1.3e-36 125.9 0.0 1.8e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ29518.1 - 3.3e-23 82.5 0.0 3.9e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2841 PF11001.8 EEQ29520.1 - 6.1e-49 165.2 0.2 9.1e-49 164.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Dicty_REP PF05086.12 EEQ29524.1 - 0.46 8.4 3.1 0.63 7.9 3.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Beta-lactamase PF00144.24 EEQ29525.1 - 4.7e-40 137.8 0.0 6.6e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EEQ29525.1 - 0.00033 20.3 0.0 0.45 10.1 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 EEQ29525.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Peptidase_S8 PF00082.22 EEQ29526.1 - 2e-22 79.8 19.4 3.8e-22 78.9 19.4 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ29526.1 - 1.4e-18 67.3 0.1 2.5e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF4090 PF13319.6 EEQ29526.1 - 0.13 12.5 0.5 0.57 10.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) SLAC1 PF03595.17 EEQ29528.1 - 4e-80 269.5 54.3 4.6e-80 269.3 54.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TraP PF07296.11 EEQ29528.1 - 9.7 5.3 5.7 0.63 9.2 0.4 1.6 2 0 0 2 2 2 0 TraP protein ABC1 PF03109.16 EEQ29529.1 - 7.1e-21 74.6 0.0 2.4e-18 66.4 0.0 2.5 1 1 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EEQ29529.1 - 0.0095 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 RIO1 family RXLR PF16810.5 EEQ29529.1 - 0.029 14.8 0.1 0.054 13.9 0.1 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity HA2 PF04408.23 EEQ29530.1 - 8.4e-14 51.8 0.0 3e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ29530.1 - 4.8e-07 30.1 0.0 1.8e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ29530.1 - 0.0027 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEQ29530.1 - 0.01 16.1 0.0 0.033 14.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EEQ29530.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 EEQ29530.1 - 0.021 15.2 0.0 0.085 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEQ29530.1 - 0.04 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 EEQ29530.1 - 0.05 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 EEQ29530.1 - 0.17 12.4 0.0 0.49 10.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter SSB PF00436.25 EEQ29531.1 - 2.4e-14 53.2 0.0 3.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.15 EEQ29532.1 - 1e-73 248.1 28.5 8e-57 192.6 14.8 3.2 2 1 1 3 3 3 3 Pheromone A receptor Pex24p PF06398.11 EEQ29532.1 - 0.0078 15.2 0.9 0.014 14.4 0.9 1.5 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF2614 PF11023.8 EEQ29532.1 - 0.24 11.5 1.7 0.3 11.2 0.3 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain Me-amine-dh_H PF06433.11 EEQ29533.1 - 0.17 10.7 0.0 0.19 10.5 0.0 1.0 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Exo_endo_phos PF03372.23 EEQ29535.1 - 1e-09 38.3 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.13 EEQ29536.1 - 2.2e-29 101.8 0.0 3.3e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family LIDHydrolase PF10230.9 EEQ29537.1 - 1.5e-70 237.8 0.0 1.8e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EEQ29537.1 - 8.4e-06 25.2 0.0 3.4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EEQ29537.1 - 1.6e-05 25.1 0.3 5.8e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 EEQ29537.1 - 0.0019 18.8 0.0 0.0031 18.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EEQ29537.1 - 0.007 16.2 0.0 0.21 11.5 0.0 2.4 1 1 1 2 2 2 1 Lipase (class 3) Abhydrolase_3 PF07859.13 EEQ29537.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1910 PF08928.10 EEQ29537.1 - 0.11 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Tom37_C PF11801.8 EEQ29537.1 - 0.12 12.4 0.2 0.28 11.2 0.0 1.6 2 0 0 2 2 2 0 Tom37 C-terminal domain DLH PF01738.18 EEQ29537.1 - 0.12 11.9 0.0 14 5.1 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family ATP-synt_I PF03899.15 EEQ29537.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 ATP synthase I chain Abhydrolase_2 PF02230.16 EEQ29537.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SMK-1 PF04802.15 EEQ29539.1 - 8.2e-35 120.4 0.2 1.1e-34 120.0 0.2 1.1 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 SLC35F PF06027.12 EEQ29541.1 - 3.7e-98 328.7 25.8 4.3e-98 328.5 25.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EEQ29541.1 - 5.9e-10 38.6 4.0 8.4e-10 38.1 4.0 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EEQ29541.1 - 4.6e-08 33.3 39.3 0.0003 21.0 16.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 EEQ29541.1 - 1.5 7.8 9.1 0.032 13.3 0.9 2.4 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS PAP_assoc PF03828.19 EEQ29544.1 - 1.2e-16 60.7 0.1 2.9e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EEQ29544.1 - 9.9e-06 25.8 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain SE PF08491.10 EEQ29546.1 - 1.1e-77 260.8 0.0 1.6e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EEQ29546.1 - 6e-10 38.9 0.0 8.9e-09 35.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EEQ29546.1 - 2e-07 30.9 0.3 5.1e-06 26.3 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EEQ29546.1 - 8.1e-07 28.5 1.0 5.2e-06 25.8 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EEQ29546.1 - 9.4e-05 21.9 0.1 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ29546.1 - 9.7e-05 22.5 0.4 0.00021 21.4 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ29546.1 - 0.00019 20.7 0.0 0.0004 19.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEQ29546.1 - 0.00026 19.8 0.5 0.00054 18.8 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EEQ29546.1 - 0.0005 19.2 0.2 0.00082 18.5 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 EEQ29546.1 - 0.00086 18.5 0.1 0.0013 17.9 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EEQ29546.1 - 0.0021 18.6 0.0 0.015 15.9 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEQ29546.1 - 0.0054 16.0 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EEQ29546.1 - 0.013 14.4 0.2 0.021 13.7 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EEQ29546.1 - 0.069 12.4 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EEQ29546.1 - 0.089 12.1 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PPR PF01535.20 EEQ29547.1 - 4.8e-05 23.3 1.2 0.4 11.0 0.0 5.7 5 0 0 5 5 5 1 PPR repeat PPR_2 PF13041.6 EEQ29547.1 - 0.019 15.2 0.5 4.4 7.6 0.0 4.1 5 0 0 5 5 5 0 PPR repeat family TPR_19 PF14559.6 EEQ29547.1 - 0.048 14.2 1.0 10 6.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 EEQ29547.1 - 0.19 11.8 0.1 8.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain MFS_1 PF07690.16 EEQ29548.1 - 3.8e-25 88.6 13.5 6.4e-25 87.8 12.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EEQ29548.1 - 0.51 8.6 6.1 2 6.6 4.6 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ferrochelatase PF00762.19 EEQ29549.1 - 9e-98 327.2 0.0 1.1e-97 327.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku_N PF03731.15 EEQ29550.1 - 6.4e-32 111.1 0.0 9.1e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EEQ29550.1 - 2e-28 98.9 1.2 5.3e-28 97.5 1.2 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Ku PF02735.16 EEQ29550.1 - 2.4e-26 92.7 0.0 2.4e-19 69.9 0.0 3.0 2 1 1 3 3 3 2 Ku70/Ku80 beta-barrel domain Adap_comp_sub PF00928.21 EEQ29551.1 - 3.2e-82 275.9 0.0 4e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EEQ29551.1 - 0.00038 20.4 0.2 0.00065 19.7 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EEQ29551.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain p450 PF00067.22 EEQ29552.1 - 5.1e-51 173.9 0.0 7.1e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Erf4 PF10256.9 EEQ29553.1 - 1.1e-41 141.6 0.0 1.7e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Lipase_3 PF01764.25 EEQ29554.1 - 0.0022 17.9 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EEQ29554.1 - 0.013 16.1 0.0 0.031 14.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 EEQ29554.1 - 0.2 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) zf-C2H2_4 PF13894.6 EEQ29555.1 - 1.2e-19 69.3 35.2 0.014 16.2 0.2 7.4 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 EEQ29555.1 - 4.6e-19 68.2 39.1 1e-07 32.1 2.1 6.5 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EEQ29555.1 - 8.9e-19 66.8 43.3 0.002 18.5 1.7 7.3 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EEQ29555.1 - 1.5e-15 57.0 39.5 1e-08 35.2 2.6 6.7 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EEQ29555.1 - 3e-13 50.0 37.2 0.0037 17.6 0.6 7.1 2 2 5 7 7 7 5 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EEQ29555.1 - 4e-10 39.4 33.7 0.013 15.5 0.7 6.8 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEQ29555.1 - 4.3e-05 23.7 35.7 0.12 12.9 0.0 7.4 6 1 1 7 7 7 3 Zinc-finger double domain DUF406 PF04175.12 EEQ29555.1 - 0.085 13.4 0.7 0.22 12.0 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF406) Zn-ribbon_8 PF09723.10 EEQ29555.1 - 0.23 11.6 0.2 0.23 11.6 0.2 6.1 5 2 1 6 6 6 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 EEQ29555.1 - 1.7 9.0 24.8 6.8 7.1 1.6 4.5 2 1 2 5 5 5 0 C2H2-type zinc ribbon zf_ZIC PF18366.1 EEQ29555.1 - 2.4 8.3 16.6 2.9 8.1 0.0 4.8 4 1 1 5 5 5 0 Zic proteins zinc finger domain Cyto_heme_lyase PF01265.17 EEQ29556.1 - 1.1e-124 415.7 0.7 1.3e-124 415.6 0.7 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase UQ_con PF00179.26 EEQ29558.1 - 4.4e-19 68.5 0.1 6.5e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.23 EEQ29559.1 - 5.6e-42 144.4 0.0 7.5e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.17 EEQ29560.1 - 5.8e-05 22.9 18.9 0.001 18.8 18.5 2.3 1 1 0 1 1 1 1 Yip1 domain UFD1 PF03152.14 EEQ29563.1 - 1.5e-31 109.2 0.0 9.4e-28 96.8 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EEQ29563.1 - 2e-06 28.0 1.5 3.2e-06 27.3 0.1 2.1 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PEX-1N PF09262.11 EEQ29563.1 - 0.082 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal DPPIV_N PF00930.21 EEQ29564.1 - 2.5e-111 371.8 4.9 4.3e-111 371.1 4.9 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EEQ29564.1 - 3.8e-36 124.6 2.5 6.4e-36 123.8 2.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EEQ29564.1 - 0.11 13.1 0.1 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family MAPEG PF01124.18 EEQ29565.1 - 1.4e-09 37.9 3.8 2.2e-09 37.3 3.7 1.3 1 1 0 1 1 1 1 MAPEG family MARVEL PF01284.23 EEQ29566.1 - 2.7e-06 27.5 11.8 4e-06 26.9 11.8 1.2 1 1 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 EEQ29566.1 - 9.9 5.6 15.4 0.75 9.3 8.8 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF829 PF05705.14 EEQ29567.1 - 1.9e-51 175.3 0.0 2.3e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) HutP PF09021.11 EEQ29568.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 HutP RNB PF00773.19 EEQ29569.1 - 2.6e-50 171.6 0.0 5.6e-48 164.0 0.0 2.7 2 1 0 2 2 2 1 RNB domain CTNNBL PF08216.11 EEQ29570.1 - 3e-38 130.1 0.1 1.1e-37 128.3 0.1 2.1 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Drf_GBD PF06371.13 EEQ29570.1 - 0.0093 15.5 0.3 0.17 11.4 0.0 2.8 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain PHTB1_C PF14728.6 EEQ29570.1 - 0.021 14.0 0.1 0.037 13.1 0.1 1.3 1 0 0 1 1 1 0 PTHB1 C-terminus HEAT_2 PF13646.6 EEQ29570.1 - 0.027 14.9 0.1 0.41 11.1 0.1 2.9 1 1 1 2 2 2 0 HEAT repeats Mo25 PF08569.11 EEQ29570.1 - 0.048 13.0 0.1 0.1 12.0 0.1 1.7 1 0 0 1 1 1 0 Mo25-like V-ATPase_H_C PF11698.8 EEQ29570.1 - 0.055 13.6 2.1 13 6.0 0.0 3.7 4 1 1 5 5 5 0 V-ATPase subunit H RNA_pol_Rpb2_6 PF00562.28 EEQ29571.1 - 2.7e-123 411.9 0.1 4.3e-123 411.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EEQ29571.1 - 1.9e-59 200.6 0.0 5.2e-59 199.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EEQ29571.1 - 3.7e-47 160.4 0.0 6.3e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EEQ29571.1 - 2.5e-33 114.3 0.0 5.3e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EEQ29571.1 - 1.2e-25 89.4 0.1 3.2e-25 88.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EEQ29571.1 - 1.3e-24 86.2 0.4 3.7e-24 84.8 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EEQ29571.1 - 7.1e-23 80.9 2.0 1.2e-22 80.3 0.4 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 EEQ29571.1 - 0.28 11.9 1.4 0.37 11.5 0.1 1.9 2 0 0 2 2 2 0 MRN-interacting protein AMPK1_CBM PF16561.5 EEQ29573.1 - 7.2e-05 22.9 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF951 PF06107.11 EEQ29573.1 - 0.37 10.7 1.7 0.67 9.9 1.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Nucleopor_Nup85 PF07575.13 EEQ29574.1 - 6.8e-22 77.8 1.2 3.4e-16 58.9 0.0 2.8 3 0 0 3 3 3 2 Nup85 Nucleoporin ADH_N PF08240.12 EEQ29576.1 - 1.4e-22 79.6 0.9 2.2e-22 79.0 0.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ29576.1 - 2.5e-15 56.6 0.1 6.2e-15 55.3 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ29576.1 - 1.8e-07 32.3 0.0 2.9e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EEQ29576.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EEQ29576.1 - 0.1 11.9 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TPR_19 PF14559.6 EEQ29577.1 - 9.4e-15 54.9 16.8 0.0023 18.4 0.1 6.9 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ29577.1 - 5.9e-11 41.9 11.8 0.00045 19.8 0.2 5.4 5 0 0 5 5 5 2 TPR repeat TPR_17 PF13431.6 EEQ29577.1 - 3.9e-09 36.3 15.9 0.00055 20.1 0.1 7.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ29577.1 - 4.1e-08 33.7 4.9 0.00046 20.8 0.1 5.2 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ29577.1 - 3.6e-05 24.2 19.1 3.3 8.8 0.0 8.8 7 3 3 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ29577.1 - 7e-05 22.9 2.7 0.023 14.8 0.1 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ29577.1 - 9.1e-05 22.3 44.0 0.49 10.6 0.2 10.7 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ29577.1 - 0.00013 21.9 34.0 0.83 10.0 0.1 9.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ29577.1 - 0.00025 20.7 29.7 0.95 9.4 0.1 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat RPN7 PF10602.9 EEQ29577.1 - 0.01 15.6 3.6 7.1 6.3 0.0 4.6 4 2 1 5 5 5 0 26S proteasome subunit RPN7 TPR_15 PF13429.6 EEQ29577.1 - 0.018 14.3 9.9 0.13 11.5 0.1 4.2 4 2 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ29577.1 - 0.019 15.1 0.1 0.019 15.1 0.1 5.8 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Urocanase PF01175.18 EEQ29577.1 - 0.023 14.4 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Urocanase Rossmann-like domain TPR_7 PF13176.6 EEQ29577.1 - 0.032 14.3 18.6 0.37 10.9 0.2 7.1 9 0 0 9 9 6 0 Tetratricopeptide repeat BTAD PF03704.17 EEQ29577.1 - 0.037 14.5 4.8 0.06 13.8 0.3 3.0 2 1 1 3 3 3 0 Bacterial transcriptional activator domain ChAPs PF09295.10 EEQ29577.1 - 0.044 12.8 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 EEQ29577.1 - 0.058 14.0 3.8 47 5.0 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EEQ29577.1 - 0.076 13.4 5.0 2.9 8.3 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ29577.1 - 0.57 10.5 24.9 0.57 10.5 1.5 6.6 8 1 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ29577.1 - 1.2 9.9 13.2 21 6.0 0.2 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2989 PF11207.8 EEQ29577.1 - 2.7 7.7 8.7 3.6 7.3 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2989) DUF3336 PF11815.8 EEQ29578.1 - 4.2e-47 159.3 0.3 6.5e-47 158.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EEQ29578.1 - 1.3e-17 64.6 0.1 8e-17 62.1 0.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase LRR_8 PF13855.6 EEQ29579.1 - 2.4e-12 46.4 28.6 3.8e-07 29.8 3.5 4.5 3 1 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EEQ29579.1 - 7e-12 45.4 5.9 0.00022 21.5 0.4 4.7 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EEQ29579.1 - 1.3e-07 31.2 6.9 1.4 9.7 0.0 6.8 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 EEQ29579.1 - 2.9e-07 30.0 11.3 0.63 10.2 0.1 5.9 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 EEQ29579.1 - 0.024 14.2 0.3 0.49 9.9 0.0 2.5 1 1 1 2 2 2 0 Leucine-rich repeat SelP_N PF04592.14 EEQ29579.1 - 1.9 7.9 7.5 3.8 6.8 7.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Metallophos PF00149.28 EEQ29580.1 - 2.4e-40 139.2 0.1 3.1e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEQ29580.1 - 1.2e-22 80.1 2.6 1.5e-22 79.8 1.7 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Arf PF00025.21 EEQ29581.1 - 5.7e-64 214.8 0.0 6.3e-64 214.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EEQ29581.1 - 2.6e-09 36.7 0.0 1.1e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EEQ29581.1 - 2.1e-08 33.8 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EEQ29581.1 - 2.7e-06 27.4 0.0 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EEQ29581.1 - 6.3e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EEQ29581.1 - 0.00024 20.7 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EEQ29581.1 - 0.0024 17.3 0.0 0.0026 17.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region mRNA_decap_C PF16741.5 EEQ29581.1 - 0.16 11.3 0.3 0.65 9.3 0.1 1.9 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus DUF2457 PF10446.9 EEQ29582.1 - 9.6e-146 486.6 32.2 9.6e-146 486.6 32.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) RPOL_N PF14700.6 EEQ29582.1 - 0.053 12.9 2.6 0.11 11.9 2.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal CH PF00307.31 EEQ29583.1 - 6.5e-09 35.9 0.0 1.3e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain Peptidase_M3 PF01432.20 EEQ29583.1 - 0.038 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M3 IQ PF00612.27 EEQ29583.1 - 0.25 11.2 1.0 0.72 9.8 1.0 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fungal_trans_2 PF11951.8 EEQ29584.1 - 1e-09 37.8 0.1 1.9e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ29584.1 - 0.012 15.7 6.7 0.029 14.5 6.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 EEQ29584.1 - 6.2 7.3 7.6 7.3 7.1 2.6 2.6 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family PCNA_C PF02747.15 EEQ29585.1 - 7.3e-50 168.4 0.0 2.1e-49 166.9 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 EEQ29585.1 - 2.3e-33 114.6 0.6 5e-33 113.5 0.6 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Vezatin PF12632.7 EEQ29585.1 - 6.2e-18 65.2 0.0 4e-09 36.3 0.0 2.5 1 1 1 2 2 2 2 Mysoin-binding motif of peroxisomes Rad1 PF02144.16 EEQ29585.1 - 0.0014 17.8 0.1 0.0023 17.0 0.1 1.3 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EEQ29585.1 - 0.0099 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 Rad9 DUF720 PF05302.11 EEQ29585.1 - 0.041 13.7 0.2 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF720) DUF1129 PF06570.11 EEQ29586.1 - 3.2 7.2 13.4 0.19 11.2 7.6 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Sec61_beta PF03911.16 EEQ29587.1 - 7.4e-18 64.3 1.0 1e-17 63.8 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family zinc_ribbon_15 PF17032.5 EEQ29589.1 - 0.0029 18.3 0.6 0.0042 17.8 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbon family RecR PF02132.15 EEQ29589.1 - 0.16 11.5 1.3 2.5 7.8 0.1 2.2 2 0 0 2 2 2 0 RecR protein Dynein_light PF01221.18 EEQ29590.1 - 2.7e-39 133.3 2.1 3.1e-39 133.2 2.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 PFU PF09070.11 EEQ29590.1 - 0.066 13.5 0.3 0.092 13.0 0.3 1.2 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) bPH_3 PF14470.6 EEQ29590.1 - 0.082 13.3 0.5 0.13 12.6 0.5 1.2 1 0 0 1 1 1 0 Bacterial PH domain DUF1805 PF08827.11 EEQ29590.1 - 0.093 13.1 0.3 0.12 12.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) RRM_1 PF00076.22 EEQ29591.1 - 7.6e-74 243.5 0.3 7.1e-19 67.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EEQ29591.1 - 6.2e-07 29.4 0.2 1 9.5 0.0 5.3 5 0 0 5 5 5 2 Limkain b1 Nup35_RRM_2 PF14605.6 EEQ29591.1 - 2.5e-06 27.4 0.1 0.031 14.3 0.0 4.6 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EEQ29591.1 - 2.4e-05 24.1 0.0 0.21 11.4 0.0 4.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EEQ29591.1 - 2.6e-05 24.2 0.0 2.6 8.2 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif RRM_5 PF13893.6 EEQ29591.1 - 7.7e-05 22.3 0.0 0.018 14.7 0.0 3.2 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 EEQ29591.1 - 0.018 15.2 0.0 4.7 7.5 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif 2 Rota_NS53 PF00981.17 EEQ29591.1 - 0.18 10.6 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Aldo_ket_red PF00248.21 EEQ29592.1 - 5.3e-41 140.7 0.0 6.9e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 EEQ29593.1 - 0.047 13.5 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GHMP_kinases_C PF08544.13 EEQ29593.1 - 0.18 12.2 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal APH PF01636.23 EEQ29594.1 - 1.1e-10 41.9 0.0 1.8e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ29594.1 - 0.23 10.3 0.1 11 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) NIF PF03031.18 EEQ29597.1 - 4e-52 176.1 0.4 5.8e-52 175.6 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4658 PF15555.6 EEQ29597.1 - 0.16 12.1 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) LRR_4 PF12799.7 EEQ29598.1 - 3.4e-31 106.7 58.9 1.2e-07 31.9 6.0 6.7 2 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEQ29598.1 - 3.2e-22 78.0 38.2 1.5e-06 27.9 5.9 6.2 2 2 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 EEQ29598.1 - 7.3e-16 58.2 19.1 9.2e-07 28.5 3.7 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EEQ29598.1 - 0.0019 18.1 27.5 0.14 12.3 0.5 6.8 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 EEQ29598.1 - 0.14 12.8 32.1 7.8 7.5 0.1 8.8 10 0 0 10 10 10 0 Leucine Rich Repeat ABC_membrane_2 PF06472.15 EEQ29599.1 - 1.9e-89 299.6 0.1 1.9e-89 299.6 0.1 1.8 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EEQ29599.1 - 1.6e-17 64.3 0.0 2.8e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 EEQ29599.1 - 0.002 18.7 0.5 0.046 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EEQ29599.1 - 0.0044 16.7 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EEQ29599.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EEQ29599.1 - 0.044 14.2 0.3 0.49 10.8 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EEQ29599.1 - 0.051 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 EEQ29599.1 - 0.084 12.3 0.0 3.6 6.9 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EEQ29599.1 - 0.088 13.2 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 EEQ29599.1 - 0.18 11.6 0.0 0.47 10.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EEQ29599.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Rx_N PF18052.1 EEQ29599.1 - 0.35 11.2 3.5 0.71 10.2 3.5 1.5 1 0 0 1 1 1 0 Rx N-terminal domain Clr2 PF10383.9 EEQ29600.1 - 3.4e-24 86.3 0.0 6.6e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 EEQ29600.1 - 2.8e-17 63.3 1.2 2.8e-17 63.3 1.2 2.1 3 0 0 3 3 3 1 Transcription-silencing protein, cryptic loci regulator Clr2 2OG-FeII_Oxy PF03171.20 EEQ29601.1 - 0.00014 22.3 0.0 0.00043 20.7 0.0 1.8 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily SAD_SRA PF02182.17 EEQ29602.1 - 2.4e-25 89.1 0.0 7.4e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 SAD/SRA domain SLY PF12485.8 EEQ29602.1 - 0.029 15.1 6.0 1.7 9.4 3.4 2.5 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein CLTH PF10607.9 EEQ29603.1 - 9.2e-32 110.0 0.0 2e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EEQ29603.1 - 9e-08 32.0 0.5 1.9e-07 31.0 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EEQ29603.1 - 0.0007 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 EEQ29603.1 - 0.0069 16.7 0.7 0.013 15.8 0.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EEQ29603.1 - 0.0079 16.1 0.3 0.015 15.2 0.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ29603.1 - 0.049 13.5 1.1 0.099 12.5 1.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EEQ29603.1 - 0.059 13.2 0.6 0.12 12.3 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ29603.1 - 0.12 12.2 1.5 0.26 11.2 1.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ29603.1 - 0.25 11.3 0.8 0.52 10.2 0.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PG_binding_1 PF01471.18 EEQ29604.1 - 0.008 16.4 1.6 0.93 9.8 0.0 3.2 3 0 0 3 3 3 2 Putative peptidoglycan binding domain zf-Tim10_DDP PF02953.15 EEQ29605.1 - 5.5e-21 74.0 0.6 5.5e-21 74.0 0.6 1.5 1 1 1 2 2 2 1 Tim10/DDP family zinc finger Tom5 PF10642.9 EEQ29605.1 - 0.029 14.4 3.9 0.33 11.0 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase SUIM_assoc PF16619.5 EEQ29605.1 - 1.9 8.6 5.3 2.8 8.1 5.3 1.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 tRNA-synt_2 PF00152.20 EEQ29606.1 - 6.2e-72 242.3 0.0 7.6e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ29606.1 - 2.7e-09 36.9 0.0 5.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EEQ29606.1 - 5.9e-05 22.7 0.0 0.023 14.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) BTB PF00651.31 EEQ29607.1 - 1.4e-06 28.5 0.0 6.5e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 EEQ29607.1 - 0.035 14.3 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain PCI PF01399.27 EEQ29608.1 - 1e-09 38.8 0.0 2.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.14 EEQ29608.1 - 0.067 13.1 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Ribosomal_L18A PF01775.17 EEQ29609.1 - 4.8e-54 181.6 2.4 6.8e-54 181.1 2.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF2887 PF11103.8 EEQ29609.1 - 0.014 15.4 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) NAD_binding_1 PF00175.21 EEQ29610.1 - 4.6e-32 110.9 0.0 7.6e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEQ29610.1 - 2.6e-23 82.2 0.0 4.8e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EEQ29610.1 - 8.7e-09 35.7 0.0 5e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HMG_box PF00505.19 EEQ29611.1 - 4.8e-13 49.3 3.5 1.2e-12 48.1 3.5 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EEQ29611.1 - 2.8e-07 31.0 3.1 7.4e-07 29.7 3.1 1.8 1 0 0 1 1 1 1 HMG-box domain Amidohydro_1 PF01979.20 EEQ29612.1 - 2.9e-75 253.7 0.8 5.1e-75 252.9 0.4 1.6 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 EEQ29612.1 - 7.9e-55 184.4 1.5 2e-54 183.1 1.5 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EEQ29612.1 - 6.5e-41 138.3 0.3 5.1e-40 135.5 0.1 2.2 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 EEQ29612.1 - 3.4e-38 129.9 0.1 8e-38 128.7 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EEQ29612.1 - 4.3e-07 29.8 0.1 0.00062 19.4 0.0 3.1 2 1 0 3 3 3 2 Amidohydrolase family Lactamase_B_2 PF12706.7 EEQ29613.1 - 3.4e-06 26.7 0.1 0.0006 19.4 0.1 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 EEQ29613.1 - 0.00042 20.5 0.0 0.0021 18.2 0.0 2.2 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 EEQ29613.1 - 0.052 13.5 0.0 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily NPR2 PF06218.11 EEQ29615.1 - 1.2e-129 432.9 0.0 7.5e-129 430.3 0.0 2.1 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Ada3 PF10198.9 EEQ29616.1 - 2.1e-51 173.5 0.0 2.1e-51 173.5 0.0 2.1 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF572 PF04502.13 EEQ29616.1 - 0.036 13.7 7.0 0.083 12.5 7.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-RING_2 PF13639.6 EEQ29618.1 - 1.1e-10 41.7 8.1 1.9e-10 40.9 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EEQ29618.1 - 6.3e-09 35.4 1.2 1.4e-08 34.3 1.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EEQ29618.1 - 5.1e-07 29.4 4.9 8.9e-07 28.7 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ29618.1 - 5.9e-06 26.1 3.8 1e-05 25.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ29618.1 - 7.4e-06 25.8 3.0 1.3e-05 25.1 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEQ29618.1 - 2.3e-05 24.3 2.5 2.3e-05 24.3 2.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EEQ29618.1 - 0.00043 20.5 6.2 0.0013 18.9 6.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EEQ29618.1 - 0.0073 16.3 2.3 0.019 15.0 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EEQ29618.1 - 0.012 15.4 5.3 0.024 14.5 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LapA_dom PF06305.11 EEQ29618.1 - 0.21 11.5 3.6 0.46 10.3 3.6 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Prok-RING_4 PF14447.6 EEQ29618.1 - 0.4 10.6 11.9 0.73 9.7 9.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EEQ29618.1 - 0.58 10.0 2.9 1.2 9.0 2.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EEQ29618.1 - 0.72 10.1 4.6 1.9 8.7 4.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 EEQ29618.1 - 7.2 6.4 6.7 0.6 9.8 1.3 1.9 2 0 0 2 2 2 0 P-11 zinc finger FRG1 PF06229.12 EEQ29619.1 - 2.6e-55 187.1 0.0 3.6e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EEQ29619.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Fascin domain ADH_N PF08240.12 EEQ29620.1 - 4e-35 120.0 4.0 6e-35 119.4 2.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ29620.1 - 4.2e-16 59.1 0.0 6.9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EEQ29620.1 - 1.6e-11 44.1 0.0 2.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EEQ29620.1 - 2.6e-07 31.7 0.0 4.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 EEQ29620.1 - 0.0069 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EEQ29620.1 - 0.0082 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 EEQ29620.1 - 0.021 14.1 0.1 0.03 13.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Staph_opine_DH PF10100.9 EEQ29620.1 - 0.23 10.1 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase NADH_4Fe-4S PF10589.9 EEQ29620.1 - 1.1 9.4 3.6 0.38 10.9 0.4 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region HECT PF00632.25 EEQ29621.1 - 7.3e-72 242.4 0.0 9.9e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L15e PF00827.17 EEQ29622.1 - 1.7e-83 279.0 13.0 4.1e-76 255.0 9.7 2.0 2 0 0 2 2 2 2 Ribosomal L15 FXMRP1_C_core PF12235.8 EEQ29622.1 - 0.44 11.2 6.4 0.07 13.8 1.2 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal AAA_assoc_2 PF16193.5 EEQ29623.1 - 0.003 17.8 0.9 0.0074 16.6 0.2 2.0 2 0 0 2 2 2 1 AAA C-terminal domain T3SSipB PF16535.5 EEQ29623.1 - 0.085 13.3 3.3 0.085 13.3 1.6 1.9 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF1840 PF08895.11 EEQ29623.1 - 0.091 13.1 0.3 0.091 13.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) WD40 PF00400.32 EEQ29624.1 - 3.6e-31 106.7 10.3 2.1e-07 31.5 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29624.1 - 7.8e-14 51.8 0.0 8.7e-05 22.8 0.1 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 EEQ29625.1 - 2.5e-12 45.4 9.0 3.1e-06 26.3 0.4 3.9 4 0 0 4 4 4 2 EF hand ZZ PF00569.17 EEQ29625.1 - 1e-11 44.4 4.2 2.1e-11 43.4 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.6 EEQ29625.1 - 5.6e-10 38.3 3.1 0.00037 20.2 0.1 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EEQ29625.1 - 5.4e-07 30.0 9.6 0.00032 21.1 0.4 3.4 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EEQ29625.1 - 1.6e-06 27.4 5.9 0.0022 17.4 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EEQ29625.1 - 3.1e-05 23.7 3.4 0.0063 16.3 0.4 3.2 3 0 0 3 3 3 2 EF-hand domain pair C1_2 PF03107.16 EEQ29625.1 - 0.0083 16.4 3.7 0.019 15.3 3.7 1.6 1 0 0 1 1 1 1 C1 domain HTH_23 PF13384.6 EEQ29626.1 - 1e-05 25.2 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 EEQ29626.1 - 8e-05 22.6 0.0 0.00036 20.5 0.0 1.9 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 EEQ29626.1 - 0.00015 22.3 0.0 0.0016 19.0 0.0 2.2 2 1 1 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.15 EEQ29626.1 - 0.00016 21.7 0.1 0.038 14.1 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DUF2774 PF11242.8 EEQ29626.1 - 0.0013 18.9 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.12 EEQ29626.1 - 0.0015 18.2 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Tnp_Tc3_2 PF01498.18 EEQ29626.1 - 0.0044 17.2 0.0 0.069 13.4 0.0 2.3 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 EEQ29626.1 - 0.005 16.6 0.0 0.064 13.0 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 EEQ29626.1 - 0.0082 16.3 0.0 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain TAL_effector PF03377.13 EEQ29626.1 - 0.093 13.1 0.1 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 TAL effector repeat TPP1 PF10341.9 EEQ29629.1 - 1.1e-17 64.0 0.0 2.4e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD RSF PF14876.6 EEQ29629.1 - 0.0018 17.3 0.4 0.0037 16.3 0.4 1.4 1 0 0 1 1 1 1 Respiratory growth transcriptional regulator PIP5K PF01504.18 EEQ29630.1 - 1.9e-36 125.7 0.9 1.2e-27 96.9 1.1 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EEQ29630.1 - 3.4e-31 108.4 0.0 6e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EEQ29630.1 - 6.1e-15 55.1 4.3 6.1e-15 55.1 4.3 2.0 2 0 0 2 2 2 1 FYVE zinc finger DZR PF12773.7 EEQ29630.1 - 0.32 11.0 6.8 0.18 11.9 2.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 EEQ29630.1 - 1.7 8.6 10.7 0.017 15.0 2.8 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S8 PF00410.19 EEQ29632.1 - 1e-15 57.8 0.0 1.5e-14 54.0 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 Sugar_tr PF00083.24 EEQ29633.1 - 5e-83 279.5 23.8 6e-83 279.2 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ29633.1 - 4.3e-15 55.5 31.0 3.2e-11 42.8 10.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EEQ29633.1 - 0.0016 17.4 5.5 0.0016 17.4 5.5 2.3 2 0 0 2 2 2 2 MFS_1 like family FAD_binding_3 PF01494.19 EEQ29635.1 - 2.4e-15 56.7 0.0 8.6e-14 51.5 0.0 3.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EEQ29635.1 - 0.00042 19.8 0.6 0.03 13.7 0.3 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase DAO PF01266.24 EEQ29635.1 - 0.00077 19.1 0.0 0.0076 15.9 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EEQ29635.1 - 0.0039 16.0 0.0 0.0063 15.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EEQ29635.1 - 0.0089 16.2 0.1 0.035 14.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ29635.1 - 0.01 15.1 0.1 0.014 14.6 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EEQ29635.1 - 0.017 14.2 0.0 0.042 12.9 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EEQ29635.1 - 0.045 14.3 0.1 0.43 11.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EEQ29635.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 EEQ29635.1 - 0.24 10.7 0.0 0.4 9.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sdh_cyt PF01127.22 EEQ29636.1 - 1.1e-23 83.6 3.4 1.8e-23 82.8 3.4 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Peptidase_M24 PF00557.24 EEQ29637.1 - 1.4e-48 165.4 0.0 1.7e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EEQ29637.1 - 3.7e-19 68.8 5.3 7.4e-19 67.8 5.3 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EEQ29637.1 - 0.022 14.9 9.2 0.022 14.9 9.2 2.1 2 0 0 2 2 2 0 MYND finger MFS_1 PF07690.16 EEQ29638.1 - 5.2e-43 147.3 44.5 5.2e-43 147.3 44.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ29638.1 - 9.8e-12 44.5 7.9 9.8e-12 44.5 7.9 3.4 3 1 0 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 EEQ29638.1 - 7.9e-05 21.3 8.6 7.9e-05 21.3 8.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 EEQ29639.1 - 3.8e-07 30.1 10.3 6.4e-07 29.4 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG-CoA_red PF00368.18 EEQ29640.1 - 9.3e-137 455.9 3.9 1.1e-136 455.6 3.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase polyprenyl_synt PF00348.17 EEQ29641.1 - 2.3e-59 200.6 0.1 3e-59 200.2 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HMG_CoA_synt_C PF08540.10 EEQ29642.1 - 2.2e-92 309.7 0.2 3e-92 309.2 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EEQ29642.1 - 5.6e-90 299.9 0.0 8.2e-90 299.3 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal GST_N PF02798.20 EEQ29643.1 - 8.3e-13 48.5 0.0 2.4e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEQ29643.1 - 1.6e-12 47.5 0.0 2.5e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EEQ29643.1 - 1.6e-08 34.8 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ29643.1 - 3.4e-08 33.4 0.7 6.9e-08 32.4 0.7 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ29643.1 - 0.00038 20.6 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EEQ29643.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 EEQ29643.1 - 0.049 14.0 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Prenyltrans PF00432.21 EEQ29644.1 - 0.1 12.4 0.6 8.4 6.2 0.0 3.1 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat DUF5530 PF17670.1 EEQ29644.1 - 0.14 11.9 0.6 0.3 10.9 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5530) Cas_Csx8 PF09657.10 EEQ29644.1 - 0.17 10.8 0.2 0.27 10.2 0.2 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) adh_short PF00106.25 EEQ29645.1 - 6.6e-14 51.8 0.0 1.6e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ29645.1 - 2e-05 24.6 0.0 3.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EEQ29645.1 - 0.00021 21.0 0.0 0.00037 20.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 EEQ29645.1 - 0.013 15.8 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_tran_WecB PF03808.13 EEQ29645.1 - 0.19 11.7 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family zf-C2H2 PF00096.26 EEQ29647.1 - 0.00017 21.8 3.9 0.38 11.3 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EEQ29647.1 - 0.00053 20.2 1.8 0.17 12.2 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ29647.1 - 0.0059 17.0 2.8 0.046 14.1 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EEQ29647.1 - 0.0067 17.2 4.5 0.87 10.6 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEQ29647.1 - 0.0093 16.4 2.1 0.014 15.8 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double domain p450 PF00067.22 EEQ29648.1 - 1.3e-42 146.1 0.0 1.6e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1769 PF08588.10 EEQ29649.1 - 2.5e-27 94.8 0.3 4.4e-27 94.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.20 EEQ29650.1 - 2.6e-96 322.8 0.0 1.4e-95 320.4 0.0 1.8 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.14 EEQ29650.1 - 0.21 12.0 0.0 0.37 11.3 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PK PF00224.21 EEQ29652.1 - 1.9e-174 579.5 4.7 2.6e-174 579.1 4.7 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EEQ29652.1 - 1.8e-37 128.1 0.0 7.2e-37 126.2 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EEQ29652.1 - 0.00058 19.1 0.4 0.0018 17.5 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EEQ29652.1 - 0.015 14.3 1.6 0.067 12.2 0.0 2.3 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.10 EEQ29653.1 - 1.7e-17 63.0 0.0 1.7e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) SUR7 PF06687.12 EEQ29654.1 - 1.7e-44 152.0 3.8 2.1e-44 151.7 3.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Ribosomal_S17_N PF16205.5 EEQ29656.1 - 5.8e-33 113.1 0.4 9.9e-33 112.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EEQ29656.1 - 3.2e-27 94.4 0.4 5.8e-27 93.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.6 EEQ29657.1 - 0 1129.8 43.3 0 1128.7 43.3 1.6 1 1 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 EEQ29657.1 - 3.3e-115 384.3 0.5 3.3e-115 384.3 0.5 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF745 PF05335.13 EEQ29657.1 - 0.03 14.1 2.8 0.072 12.8 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Pil1 PF13805.6 EEQ29658.1 - 2.5e-126 420.6 0.0 3.6e-126 420.1 0.0 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 EEQ29658.1 - 0.087 12.2 1.2 0.18 11.2 0.6 1.7 1 1 0 1 1 1 0 FAM92 protein XPG_N PF00752.17 EEQ29659.1 - 3.3e-35 120.6 0.0 1.8e-34 118.2 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EEQ29659.1 - 2.2e-25 88.8 0.0 6.4e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EEQ29659.1 - 4.9e-05 23.9 0.0 0.00018 22.0 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EEQ29659.1 - 0.02 15.5 0.0 0.043 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Transposase_20 PF02371.16 EEQ29659.1 - 0.03 14.6 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family UIM PF02809.20 EEQ29659.1 - 0.52 10.3 6.4 0.048 13.6 0.6 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif WD40 PF00400.32 EEQ29660.1 - 6.1e-09 36.4 4.9 4.9e-06 27.2 0.2 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40 PF00400.32 EEQ29661.1 - 3.3e-06 27.7 0.5 0.9 10.5 0.1 4.5 3 1 0 3 3 3 2 WD domain, G-beta repeat LSM PF01423.22 EEQ29662.1 - 0.0026 17.4 0.0 0.039 13.6 0.0 2.0 2 0 0 2 2 2 1 LSM domain Metallophos PF00149.28 EEQ29663.1 - 2.5e-33 116.3 0.1 3.7e-33 115.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEQ29663.1 - 2.7e-15 56.5 0.0 4.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 EEQ29664.1 - 1.7e-13 50.8 10.9 0.00019 22.1 0.1 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29664.1 - 7.4e-12 45.4 0.0 1.9e-06 28.1 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EEQ29664.1 - 0.00051 19.8 0.5 0.0017 18.1 0.5 2.0 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.11 EEQ29664.1 - 0.003 17.5 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EEQ29664.1 - 0.02 14.8 3.4 8.7 6.4 0.2 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SprA-related PF12118.8 EEQ29664.1 - 9.5 5.2 12.0 15 4.6 12.0 1.2 1 0 0 1 1 1 0 SprA-related family DUF3128 PF11326.8 EEQ29665.1 - 1.1 9.7 4.5 74 3.8 4.5 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Csm1_N PF18504.1 EEQ29666.1 - 0.061 13.7 0.6 0.061 13.7 0.6 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain YabA PF06156.13 EEQ29666.1 - 0.23 12.1 0.9 1 10.0 0.9 2.2 1 0 0 1 1 1 0 Initiation control protein YabA F-box_4 PF15966.5 EEQ29667.1 - 0.0021 17.9 0.1 0.0041 17.0 0.1 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EEQ29667.1 - 0.015 15.1 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 F-box-like Gpr1_Fun34_YaaH PF01184.19 EEQ29668.1 - 3.7e-79 265.1 15.1 4.4e-79 264.9 15.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ANTH PF07651.16 EEQ29669.1 - 2.1e-57 194.3 0.3 3.2e-57 193.6 0.3 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EEQ29669.1 - 5.9e-10 39.3 0.1 3.2e-09 36.9 0.0 2.3 3 0 0 3 3 3 1 ENTH domain Peptidase_S64 PF08192.11 EEQ29669.1 - 5.1 5.5 12.2 7.5 4.9 12.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Memo PF01875.17 EEQ29671.1 - 3.8e-62 209.9 0.0 4.5e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Rad4 PF03835.15 EEQ29672.1 - 1.7e-15 57.0 2.9 3e-15 56.2 2.9 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EEQ29672.1 - 1.2e-13 51.5 0.6 2.6e-13 50.4 0.6 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.32 EEQ29674.1 - 3e-11 43.7 9.4 0.064 14.2 0.0 9.4 10 1 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29674.1 - 2.8e-09 37.1 0.5 0.079 13.3 0.0 5.8 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EEQ29674.1 - 0.00016 21.4 2.0 0.00016 21.4 2.0 2.8 3 1 0 3 3 3 1 PQQ-like domain Lactonase PF10282.9 EEQ29674.1 - 0.0017 17.7 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Ge1_WD40 PF16529.5 EEQ29674.1 - 0.11 11.4 0.2 2.8 6.8 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 EEQ29674.1 - 0.18 11.8 1.0 27 4.9 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Cyclin_N PF00134.23 EEQ29678.1 - 8.9e-25 86.9 0.1 3.4e-24 85.0 0.1 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEQ29678.1 - 1.7e-08 34.6 1.8 1.7e-08 34.6 1.8 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain Acyl_transf_3 PF01757.22 EEQ29679.1 - 5.7e-26 91.4 21.0 8.3e-26 90.8 21.0 1.3 1 0 0 1 1 1 1 Acyltransferase family Caps_synth_CapC PF14102.6 EEQ29679.1 - 0.16 12.4 0.2 0.16 12.4 0.2 2.5 4 0 0 4 4 4 0 Capsule biosynthesis CapC Pyr_redox_2 PF07992.14 EEQ29680.1 - 2.3e-15 56.6 0.1 9.5e-14 51.3 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ29680.1 - 0.00022 20.6 0.0 0.034 13.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ29680.1 - 0.0074 16.3 0.5 1.7 8.6 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EEQ29680.1 - 0.027 14.7 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EEQ29680.1 - 0.077 12.2 0.4 0.2 10.9 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain Tub PF01167.18 EEQ29680.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Tub family NAPRTase_N PF17767.1 EEQ29682.1 - 0.17 12.3 0.6 0.29 11.5 0.6 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain FKBP_C PF00254.28 EEQ29683.1 - 7.7e-32 109.5 0.0 9.7e-32 109.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RXLR PF16810.5 EEQ29683.1 - 0.11 12.9 0.6 0.13 12.7 0.6 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Cyt-b5 PF00173.28 EEQ29684.1 - 1.6e-16 60.2 0.0 2.4e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zip PF02535.22 EEQ29685.1 - 3.7e-66 223.6 7.9 4.2e-66 223.4 7.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Tom37 PF10568.9 EEQ29686.1 - 3e-35 121.3 0.0 3.6e-34 117.7 0.0 2.4 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EEQ29686.1 - 4.6e-08 32.7 0.0 1.7e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF3558 PF12079.8 EEQ29687.1 - 0.077 13.0 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) DUF2721 PF11026.8 EEQ29687.1 - 0.48 10.3 1.9 18 5.2 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) NAPRTase PF04095.16 EEQ29691.1 - 1.7e-55 188.3 0.1 4.7e-28 98.4 0.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EEQ29691.1 - 5.9e-34 117.1 0.1 1e-33 116.4 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Syntaxin PF00804.25 EEQ29693.1 - 2.3e-18 66.6 12.0 2.3e-18 66.6 12.0 1.9 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 EEQ29693.1 - 5.1e-09 36.4 6.4 3e-08 34.0 0.5 2.7 2 1 0 2 2 2 1 Syntaxin-like protein Use1 PF09753.9 EEQ29693.1 - 1.1e-06 28.5 5.3 1.7e-06 28.0 5.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 EEQ29693.1 - 2.1e-05 24.4 17.5 0.00015 21.7 15.2 3.1 2 1 0 2 2 2 1 SNARE domain Spectrin PF00435.21 EEQ29693.1 - 0.0011 19.4 7.7 0.13 12.8 0.0 3.3 3 1 0 3 3 3 1 Spectrin repeat MCU PF04678.13 EEQ29693.1 - 0.0029 17.7 0.7 0.0029 17.7 0.7 2.6 2 1 0 2 2 2 1 Mitochondrial calcium uniporter COG2 PF06148.11 EEQ29693.1 - 0.0052 16.9 0.2 0.0052 16.9 0.2 2.8 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 TRP PF06011.12 EEQ29693.1 - 0.021 13.6 0.1 0.028 13.2 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF2207 PF09972.9 EEQ29693.1 - 0.022 13.5 0.0 0.038 12.8 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ETRAMP PF09716.10 EEQ29693.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MT0933_antitox PF14013.6 EEQ29693.1 - 0.097 13.0 0.3 0.57 10.5 0.1 2.3 2 0 0 2 2 2 0 MT0933-like antitoxin protein SP_C-Propep PF08999.10 EEQ29693.1 - 0.11 12.2 2.7 0.2 11.4 2.7 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Baculo_F PF12259.8 EEQ29693.1 - 0.12 10.9 11.5 0.18 10.3 0.1 2.6 1 1 0 2 2 2 0 Baculovirus F protein DUF5345 PF17280.2 EEQ29693.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.1 2 0 0 2 2 1 0 Family of unknown function (DUF5345) Orf78 PF06024.12 EEQ29693.1 - 0.13 12.5 0.4 0.13 12.5 0.4 2.3 2 1 0 2 2 2 0 Orf78 (ac78) Gp-FAR-1 PF05823.12 EEQ29693.1 - 0.15 12.4 3.9 3 8.2 2.6 2.4 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PBP1_TM PF14812.6 EEQ29693.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Baculo_PEP_C PF04513.12 EEQ29693.1 - 0.21 11.6 1.1 19 5.3 0.0 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EEQ29693.1 - 0.23 11.6 11.8 0.61 10.3 0.4 3.0 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Gp58 PF07902.11 EEQ29693.1 - 0.26 9.5 8.2 0.33 9.2 8.2 1.2 1 0 0 1 1 1 0 gp58-like protein Pox_EPC_I2-L1 PF12575.8 EEQ29693.1 - 0.29 11.4 1.9 0.82 9.9 1.9 1.7 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 CENP-H PF05837.12 EEQ29693.1 - 0.41 11.1 10.0 2.2 8.7 0.5 2.8 1 1 2 3 3 3 0 Centromere protein H (CENP-H) YtxH PF12732.7 EEQ29693.1 - 0.54 10.8 3.3 75 4.0 3.3 3.0 1 1 0 1 1 1 0 YtxH-like protein Fusion_F0 PF13044.6 EEQ29693.1 - 0.58 8.7 4.0 0.43 9.2 1.9 1.7 2 0 0 2 2 2 0 Fusion glycoprotein F0, Isavirus Baculo_11_kDa PF06143.11 EEQ29693.1 - 0.58 9.8 5.4 2.2 7.9 5.4 2.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family Tweety PF04906.13 EEQ29693.1 - 0.59 8.7 3.4 0.44 9.1 1.5 1.7 2 0 0 2 2 2 0 Tweety BLOC1_2 PF10046.9 EEQ29693.1 - 0.75 10.1 5.9 4.7 7.6 0.5 3.2 3 1 2 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 EEQ29693.1 - 1.1 8.6 12.3 11 5.2 12.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) 7tm_7 PF08395.12 EEQ29693.1 - 1.2 8.2 8.9 2 7.5 0.5 2.7 3 0 0 3 3 3 0 7tm Chemosensory receptor zf-CpG_bind_C PF12269.8 EEQ29693.1 - 1.4 8.6 9.5 4.2 7.1 0.7 2.5 2 1 1 3 3 3 0 CpG binding protein zinc finger C terminal domain ISG65-75 PF11727.8 EEQ29693.1 - 1.6 7.9 9.2 8.9 5.5 2.7 2.7 2 1 1 3 3 3 0 Invariant surface glycoprotein TMPIT PF07851.13 EEQ29693.1 - 6.5 5.9 9.0 5.5 6.1 0.5 2.3 1 1 1 2 2 2 0 TMPIT-like protein BolA PF01722.18 EEQ29694.1 - 1.9e-30 104.9 0.6 2.4e-30 104.6 0.6 1.1 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.11 EEQ29694.1 - 0.0074 16.9 0.1 0.0095 16.6 0.1 1.3 1 1 0 1 1 1 1 Replication protein A C terminal AMP-binding PF00501.28 EEQ29695.1 - 2.8e-63 214.0 0.0 4.3e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ29695.1 - 3e-11 44.1 0.0 5.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.18 EEQ29696.1 - 1.4e-52 177.6 1.7 1.9e-52 177.3 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.12 EEQ29697.1 - 2.2e-21 75.9 0.3 3.6e-21 75.2 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.20 EEQ29698.1 - 2.3e-27 94.8 3.3 9.3e-27 92.8 1.0 2.6 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EEQ29698.1 - 3.5e-22 77.6 0.0 5.7e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EEQ29698.1 - 1.2 9.7 11.2 2.5 8.7 11.2 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Bac_rhodopsin PF01036.18 EEQ29700.1 - 5.5e-41 140.6 20.3 6.6e-41 140.3 20.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Phage_holin_3_6 PF07332.11 EEQ29700.1 - 0.014 15.5 10.8 0.1 12.7 1.7 3.0 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3810 PF12725.7 EEQ29700.1 - 0.042 13.2 14.3 0.33 10.2 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) tRNA-synt_1 PF00133.22 EEQ29701.1 - 2.1e-160 534.9 0.0 2.9e-160 534.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) UPF0183 PF03676.14 EEQ29701.1 - 3.6e-55 187.8 0.0 6e-39 134.5 0.0 2.5 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Anticodon_1 PF08264.13 EEQ29701.1 - 3.1e-22 79.2 1.8 5.9e-22 78.3 1.8 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EEQ29701.1 - 1.1e-19 70.5 0.0 1.1e-12 47.4 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EEQ29701.1 - 0.045 13.1 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EEQ29701.1 - 0.17 11.3 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 EEQ29701.1 - 3.3 7.7 7.8 11 6.0 7.7 2.0 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS Kinesin PF00225.23 EEQ29702.1 - 8.4e-107 356.9 0.3 2.5e-106 355.4 0.3 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ29702.1 - 1.4e-25 90.0 0.8 4.5e-25 88.3 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 EEQ29702.1 - 3.9e-06 27.3 0.6 3.9e-06 27.3 0.6 5.8 5 2 2 7 7 7 1 Kinesin-associated microtubule-binding CD24 PF14984.6 EEQ29703.1 - 0.37 11.1 0.2 0.37 11.1 0.2 2.8 3 0 0 3 3 3 0 CD24 protein zf-ANAPC11 PF12861.7 EEQ29704.1 - 7.8e-47 157.3 11.1 8.8e-47 157.1 11.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EEQ29704.1 - 4.7e-22 78.0 10.0 6.4e-22 77.6 10.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEQ29704.1 - 1.2e-08 35.2 15.2 3.2e-07 30.6 15.1 2.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EEQ29704.1 - 2.6e-05 24.1 10.0 8.7e-05 22.5 5.7 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EEQ29704.1 - 3e-05 23.8 4.3 3e-05 23.8 4.3 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ29704.1 - 0.00027 20.7 13.0 0.0011 18.8 13.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ29704.1 - 0.00032 20.5 11.3 0.00038 20.3 6.2 2.2 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EEQ29704.1 - 0.00088 19.0 10.9 0.0012 18.6 1.0 2.7 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EEQ29704.1 - 0.0063 16.7 16.2 0.14 12.3 16.2 3.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.6 EEQ29704.1 - 0.018 15.0 15.5 0.21 11.5 15.8 2.6 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EEQ29704.1 - 0.044 13.4 12.9 0.085 12.5 10.9 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 EEQ29704.1 - 0.067 13.0 0.9 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 EEQ29704.1 - 0.096 12.6 13.9 5.6 6.9 14.1 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EEQ29704.1 - 0.21 11.7 12.5 0.19 11.9 9.5 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EEQ29704.1 - 0.3 11.0 4.3 0.52 10.2 4.3 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit YacG PF03884.14 EEQ29704.1 - 0.33 10.7 0.3 0.33 10.7 0.3 2.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-C2H2_9 PF16293.5 EEQ29704.1 - 0.52 10.2 5.9 4.5 7.2 0.1 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-RING_11 PF17123.5 EEQ29704.1 - 0.56 10.0 12.7 0.96 9.2 9.4 2.7 2 1 0 2 2 2 0 RING-like zinc finger PHD PF00628.29 EEQ29704.1 - 0.67 9.9 13.4 2.8 7.9 13.4 2.0 1 1 0 1 1 1 0 PHD-finger DZR PF12773.7 EEQ29704.1 - 0.68 10.0 11.4 1.8 8.7 5.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon TerY_C PF15616.6 EEQ29704.1 - 0.91 9.6 6.8 1.3 9.1 6.8 1.4 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING-like PF08746.11 EEQ29704.1 - 3.1 8.2 12.2 20 5.6 12.2 2.2 1 1 0 1 1 1 0 RING-like domain Opy2 PF09463.10 EEQ29704.1 - 5.8 7.3 10.7 6.6 7.1 6.3 2.4 2 1 0 2 2 2 0 Opy2 protein RINGv PF12906.7 EEQ29704.1 - 8.2 6.6 14.3 7.7 6.7 11.8 2.2 1 1 1 2 2 2 0 RING-variant domain Rhodanese PF00581.20 EEQ29705.1 - 1.3e-16 61.0 0.0 3.1e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain PIN_4 PF13638.6 EEQ29706.1 - 5e-05 23.6 0.1 0.023 15.0 0.0 2.5 3 0 0 3 3 3 2 PIN domain DUF2007 PF09413.10 EEQ29707.1 - 0.018 15.2 0.0 0.077 13.2 0.0 2.0 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein PdxA PF04166.12 EEQ29707.1 - 0.2 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Metallophos_2 PF12850.7 EEQ29708.1 - 6.2e-08 33.0 0.4 1.6e-06 28.4 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EEQ29708.1 - 6.6e-08 33.3 0.7 1e-07 32.6 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RPEL PF02755.15 EEQ29709.1 - 1.5e-25 88.1 4.4 4.8e-08 32.4 0.2 3.4 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.6 EEQ29709.1 - 0.046 14.3 0.4 0.61 10.6 0.1 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Translin PF01997.16 EEQ29710.1 - 1.1e-60 205.2 0.0 1.6e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Translin family DUF3375 PF11855.8 EEQ29710.1 - 0.0079 15.2 1.0 0.027 13.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3375) Mt_ATP_synt PF15704.5 EEQ29710.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit NPH3 PF03000.14 EEQ29710.1 - 0.13 11.9 0.3 0.28 10.8 0.1 1.5 1 1 0 1 1 1 0 NPH3 family LEF-8 PF04941.12 EEQ29710.1 - 0.16 10.2 0.0 0.19 10.0 0.0 1.0 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) Mannosyl_trans PF05007.13 EEQ29711.1 - 9.2e-79 264.9 12.7 1.6e-78 264.2 12.7 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EEQ29711.1 - 5e-13 48.9 3.6 5e-13 48.9 3.6 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EEQ29711.1 - 2.4e-07 30.7 2.2 2.4e-07 30.7 2.2 2.7 4 0 0 4 4 4 1 Glycosyltransferase family 87 F-box-like PF12937.7 EEQ29712.1 - 0.0034 17.2 0.0 0.013 15.4 0.0 2.1 1 1 0 1 1 1 1 F-box-like FYRC PF05965.14 EEQ29712.1 - 0.12 12.6 0.0 8 6.7 0.0 2.7 2 0 0 2 2 2 0 F/Y rich C-terminus Menin PF05053.13 EEQ29713.1 - 0.8 8.0 5.0 1.3 7.3 5.0 1.3 1 0 0 1 1 1 0 Menin SQS_PSY PF00494.19 EEQ29714.1 - 9.6e-39 133.5 0.0 1.6e-38 132.7 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase DUF2951 PF11166.8 EEQ29714.1 - 0.031 14.5 0.0 4.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF4328 PF14219.6 EEQ29714.1 - 0.21 11.1 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Amidohydro_2 PF04909.14 EEQ29715.1 - 3.4e-10 40.2 0.0 5.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EEQ29715.1 - 3.7e-10 39.7 0.0 5.8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.6 EEQ29715.1 - 0.0011 19.4 0.1 0.016 15.7 0.1 2.4 2 1 0 3 3 3 1 CoA binding domain DnaJ-X PF14308.6 EEQ29716.1 - 3.4e-79 265.2 5.5 3.4e-79 265.2 5.5 3.1 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EEQ29716.1 - 4.4e-25 87.6 0.1 1.2e-24 86.2 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Condensin2nSMC PF12422.8 EEQ29716.1 - 0.037 14.2 0.1 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit OrfB_IS605 PF01385.19 EEQ29716.1 - 0.2 11.9 3.5 0.52 10.6 3.5 1.6 1 0 0 1 1 1 0 Probable transposase IMS PF00817.20 EEQ29718.1 - 7.5e-43 146.1 0.6 1.8e-42 144.8 0.6 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EEQ29718.1 - 1.8e-14 54.5 0.2 4.2e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EEQ29718.1 - 7.1e-06 26.1 0.0 1.9e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Moricin PF06451.11 EEQ29718.1 - 0.064 13.0 0.2 8.6 6.2 0.0 3.0 3 0 0 3 3 3 0 Moricin Pullulanase_Ins PF18494.1 EEQ29718.1 - 0.07 13.6 0.0 0.27 11.7 0.0 2.0 1 0 0 1 1 1 0 Pullulanase Ins domain NIBRIN_BRCT_II PF16508.5 EEQ29719.1 - 1.6e-31 109.1 0.0 3.5e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 EEQ29719.1 - 7.7e-05 23.0 0.3 0.00017 21.9 0.3 1.6 1 0 0 1 1 1 1 FHA domain Acetyltransf_1 PF00583.25 EEQ29720.1 - 0.0093 16.2 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ferritin_2 PF13668.6 EEQ29721.1 - 1.2e-14 54.7 0.1 1.9e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.24 EEQ29722.1 - 6.2e-21 74.8 22.8 2e-12 46.7 6.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 EEQ29724.1 - 2.4e-27 96.0 0.0 1.1e-25 90.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29724.1 - 9.6e-12 44.7 0.0 4e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase AMP-binding PF00501.28 EEQ29725.1 - 3.1e-74 250.1 0.0 3.7e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ29725.1 - 6.6e-12 46.2 0.5 6.6e-12 46.2 0.5 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EEQ29726.1 - 1.1e-26 93.6 21.9 1.1e-21 77.1 14.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily CLN3 PF02487.17 EEQ29726.1 - 0.00053 19.1 0.0 0.026 13.6 0.0 2.4 2 0 0 2 2 2 2 CLN3 protein Sensor PF13796.6 EEQ29726.1 - 0.0062 16.6 7.8 0.0062 16.6 7.8 3.0 1 1 1 2 2 2 1 Putative sensor CoA_binding_2 PF13380.6 EEQ29728.1 - 8.9e-28 97.1 0.0 1.1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.12 EEQ29730.1 - 1e-23 83.8 0.0 2.4e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ29730.1 - 1.3e-21 77.1 0.0 3.2e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ29730.1 - 2.4e-13 50.2 0.0 3.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ29730.1 - 7.1e-13 48.7 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ29730.1 - 8.2e-12 45.7 0.0 1.7e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ29730.1 - 3.6e-09 36.3 0.0 1.1e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EEQ29730.1 - 9.5e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EEQ29730.1 - 0.00023 20.7 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 EEQ29730.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_18 PF12847.7 EEQ29730.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EEQ29730.1 - 0.0088 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EEQ29730.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EEQ29730.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_8 PF05148.15 EEQ29730.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.12 EEQ29730.1 - 0.043 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.14 EEQ29730.1 - 0.064 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB NodS PF05401.11 EEQ29730.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) HIT PF01230.23 EEQ29731.1 - 1.3e-24 86.8 0.6 4.2e-24 85.1 0.2 1.9 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EEQ29731.1 - 4.3e-08 33.6 0.1 8.4e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 EEQ29731.1 - 0.0033 17.2 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain CwfJ_C_1 PF04677.15 EEQ29731.1 - 0.0038 17.1 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 dCMP_cyt_deam_1 PF00383.23 EEQ29732.1 - 1.5e-05 24.8 0.1 2.1e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Chitin_synth_1 PF01644.17 EEQ29733.1 - 6.8e-77 257.0 0.0 1.3e-76 256.1 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EEQ29733.1 - 2.4e-28 97.9 0.1 5.4e-28 96.8 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EEQ29733.1 - 2.4e-23 82.6 0.4 7e-20 71.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EEQ29733.1 - 1.4e-06 28.4 0.1 4.3e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EEQ29733.1 - 0.059 13.2 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 AFG1_ATPase PF03969.16 EEQ29734.1 - 3.1e-89 299.4 0.0 6.4e-85 285.2 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EEQ29734.1 - 0.0025 18.2 0.1 0.84 10.0 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EEQ29734.1 - 0.0051 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EEQ29734.1 - 0.011 16.1 0.0 0.048 14.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ29734.1 - 0.1 12.9 0.0 0.4 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EEQ29734.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SH3_1 PF00018.28 EEQ29735.1 - 8.4e-25 86.1 1.5 2.5e-11 43.0 0.0 3.3 3 0 0 3 3 3 2 SH3 domain PX PF00787.24 EEQ29735.1 - 6.1e-14 52.0 0.0 1.4e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 EEQ29735.1 - 9.8e-13 47.7 2.6 1.5e-05 24.8 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 EEQ29735.1 - 6.4e-10 38.6 0.0 2.2e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 EEQ29735.1 - 1.1e-07 31.7 0.5 2.2e-07 30.7 0.5 1.5 1 0 0 1 1 1 1 PB1 domain zf-XS PF03470.14 EEQ29735.1 - 0.28 11.5 3.0 0.75 10.1 3.0 1.8 1 0 0 1 1 1 0 XS zinc finger domain Pex14_N PF04695.13 EEQ29735.1 - 8 7.1 24.4 19 5.9 0.9 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SAC3_GANP PF03399.16 EEQ29736.1 - 3.3e-24 85.8 1.1 7.5e-22 78.1 1.1 2.3 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EEQ29736.1 - 9e-06 25.7 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family EAP30 PF04157.16 EEQ29737.1 - 2.7e-42 144.7 0.4 3.5e-42 144.3 0.4 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 EEQ29737.1 - 1.4e-23 82.1 2.0 2.5e-23 81.2 2.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 EEQ29737.1 - 2.6e-14 53.2 0.0 4.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.15 EEQ29737.1 - 0.00071 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zf-MIZ PF02891.20 EEQ29737.1 - 0.04 13.7 0.1 0.096 12.5 0.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RanBP PF00641.18 EEQ29737.1 - 5.7 6.4 4.9 0.57 9.5 0.4 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others F-box PF00646.33 EEQ29739.1 - 0.00013 21.8 0.8 0.00045 20.0 0.8 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EEQ29739.1 - 0.0011 18.8 0.3 0.0027 17.6 0.3 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EEQ29739.1 - 0.066 13.1 0.7 0.066 13.1 0.7 2.2 2 1 0 2 2 2 0 F-box-like AA_permease PF00324.21 EEQ29740.1 - 5.8e-134 447.3 46.4 6.6e-134 447.1 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ29740.1 - 6.3e-26 91.2 53.7 8.1e-26 90.8 53.7 1.1 1 0 0 1 1 1 1 Amino acid permease PHP PF02811.19 EEQ29741.1 - 1.8e-11 44.6 0.0 4.7e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 PHP domain ATPgrasp_N PF18130.1 EEQ29742.1 - 0.036 14.6 0.0 0.066 13.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp N-terminal domain AAT PF03417.16 EEQ29743.1 - 3.2e-30 105.5 0.0 3.9e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase MTP18 PF10558.9 EEQ29744.1 - 6.7e-83 276.8 0.4 1.6e-82 275.6 0.4 1.6 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) MFS_1 PF07690.16 EEQ29746.1 - 3.1e-37 128.3 40.6 1e-25 90.5 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cys_Met_Meta_PP PF01053.20 EEQ29747.1 - 1e-140 468.6 0.0 1.2e-140 468.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEQ29747.1 - 1.9e-06 27.3 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ29747.1 - 6.8e-05 22.0 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ29747.1 - 0.00049 19.5 0.0 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EEQ29747.1 - 0.013 14.8 0.0 0.039 13.2 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase AAA PF00004.29 EEQ29748.1 - 5.8e-37 127.1 0.0 1.6e-36 125.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ29748.1 - 1.4e-08 34.4 0.0 3.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 EEQ29748.1 - 1.4e-05 25.1 0.0 9.9e-05 22.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EEQ29748.1 - 2e-05 24.6 0.1 0.00029 20.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEQ29748.1 - 2.3e-05 24.2 0.0 4.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEQ29748.1 - 2.4e-05 24.8 1.1 0.00039 20.8 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EEQ29748.1 - 0.00023 21.3 0.0 0.00051 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EEQ29748.1 - 0.00039 20.7 0.3 0.0062 16.8 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.6 EEQ29748.1 - 0.00058 20.0 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EEQ29748.1 - 0.00072 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EEQ29748.1 - 0.00076 20.0 0.0 0.0029 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EEQ29748.1 - 0.001 18.5 0.1 0.002 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EEQ29748.1 - 0.0013 18.4 0.1 0.029 13.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EEQ29748.1 - 0.0015 18.9 0.0 0.0054 17.1 0.0 2.1 2 1 0 2 2 1 1 RNA helicase Parvo_NS1 PF01057.17 EEQ29748.1 - 0.002 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TniB PF05621.11 EEQ29748.1 - 0.0033 16.9 0.0 2.9 7.2 0.0 2.5 1 1 1 2 2 2 2 Bacterial TniB protein NACHT PF05729.12 EEQ29748.1 - 0.0041 17.0 0.1 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 EEQ29748.1 - 0.0084 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EEQ29748.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EEQ29748.1 - 0.014 15.6 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 EEQ29748.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 EEQ29748.1 - 0.015 15.2 0.1 0.056 13.4 0.1 1.8 1 1 1 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 EEQ29748.1 - 0.026 15.0 0.3 0.09 13.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 EEQ29748.1 - 0.058 13.2 0.4 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEQ29748.1 - 0.059 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 EEQ29748.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ATPase_2 PF01637.18 EEQ29748.1 - 0.072 13.0 0.0 0.24 11.3 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EEQ29748.1 - 0.075 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 EEQ29748.1 - 0.082 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EOS1 PF12326.8 EEQ29748.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 N-glycosylation protein AAA_6 PF12774.7 EEQ29748.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TIP49 PF06068.13 EEQ29748.1 - 0.12 11.6 0.0 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 EEQ29748.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 EEQ29748.1 - 0.17 11.6 0.6 21 4.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Csm1 PF12539.8 EEQ29749.1 - 1.7e-31 108.6 0.3 4.9e-31 107.2 0.1 1.9 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 Atg14 PF10186.9 EEQ29749.1 - 0.00022 20.4 9.7 0.0004 19.6 9.7 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 EEQ29749.1 - 0.00063 17.8 6.6 0.00063 17.8 6.6 1.7 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family MscS_porin PF12795.7 EEQ29749.1 - 0.0021 17.6 14.4 0.0052 16.4 14.4 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain TolA_bind_tri PF16331.5 EEQ29749.1 - 0.0028 17.7 10.1 0.016 15.2 9.9 2.5 1 1 0 1 1 1 1 TolA binding protein trimerisation Filament PF00038.21 EEQ29749.1 - 0.005 16.5 11.5 0.01 15.4 11.5 1.5 1 0 0 1 1 1 1 Intermediate filament protein Cep57_CLD PF14073.6 EEQ29749.1 - 0.0087 16.1 14.1 0.03 14.4 14.1 1.9 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 EzrA PF06160.12 EEQ29749.1 - 0.0093 14.2 11.3 0.014 13.6 11.3 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc42p PF11544.8 EEQ29749.1 - 0.014 15.4 6.6 0.014 15.4 6.6 2.9 1 1 2 3 3 3 0 Spindle pole body component Spc42p PKcGMP_CC PF16808.5 EEQ29749.1 - 0.028 14.3 1.7 0.028 14.3 1.7 2.2 2 0 0 2 2 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 EEQ29749.1 - 0.029 13.3 15.6 0.055 12.3 15.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein RPW8 PF05659.11 EEQ29749.1 - 0.062 13.0 4.3 0.11 12.2 4.3 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2968 PF11180.8 EEQ29749.1 - 0.067 12.8 11.0 0.13 11.8 11.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Prominin PF05478.11 EEQ29749.1 - 0.07 11.1 8.3 0.096 10.6 8.3 1.1 1 0 0 1 1 1 0 Prominin COG5 PF10392.9 EEQ29749.1 - 0.082 13.1 7.7 0.16 12.1 7.7 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 CREPT PF16566.5 EEQ29749.1 - 0.13 12.5 10.2 0.29 11.3 10.2 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Allexi_40kDa PF05549.11 EEQ29749.1 - 0.14 11.7 7.9 0.05 13.1 5.2 1.6 2 0 0 2 2 1 0 Allexivirus 40kDa protein Macoilin PF09726.9 EEQ29749.1 - 0.14 10.7 22.2 0.19 10.3 22.2 1.1 1 0 0 1 1 1 0 Macoilin family Alanine_zipper PF11839.8 EEQ29749.1 - 0.17 12.2 11.7 1.5 9.3 11.7 2.7 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Erp_C PF06780.11 EEQ29749.1 - 0.22 11.5 6.5 2.4 8.2 0.2 2.5 1 1 1 2 2 2 0 Erp protein C-terminus Sulfatase_C PF14707.6 EEQ29749.1 - 0.27 12.0 1.2 0.62 10.8 1.2 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF3450 PF11932.8 EEQ29749.1 - 0.37 10.1 13.6 0.78 9.0 13.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.9 EEQ29749.1 - 0.45 10.4 11.4 1.4 8.8 11.4 1.9 1 0 0 1 1 1 0 Axonemal dynein light chain HAUS-augmin3 PF14932.6 EEQ29749.1 - 0.47 10.0 14.0 0.88 9.1 14.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 PhoU PF01895.19 EEQ29749.1 - 0.56 10.7 2.4 1.2 9.6 0.4 2.5 2 1 0 3 3 1 0 PhoU domain FliS PF02561.14 EEQ29749.1 - 0.58 10.4 6.5 0.62 10.4 4.3 2.1 2 0 0 2 2 2 0 Flagellar protein FliS DUF812 PF05667.11 EEQ29749.1 - 0.62 8.9 22.1 2.8 6.7 22.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) IFT57 PF10498.9 EEQ29749.1 - 0.63 8.9 22.2 0.031 13.3 11.9 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Sec34 PF04136.15 EEQ29749.1 - 0.67 9.8 10.4 1.7 8.5 10.4 1.7 1 0 0 1 1 1 0 Sec34-like family Rx_N PF18052.1 EEQ29749.1 - 0.69 10.2 5.3 5.9 7.2 5.3 2.4 1 1 0 1 1 1 0 Rx N-terminal domain TMPIT PF07851.13 EEQ29749.1 - 0.72 9.0 11.6 1.2 8.3 11.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 EEQ29749.1 - 0.74 8.6 1.7 1.1 8.1 1.7 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DHR10 PF18595.1 EEQ29749.1 - 0.75 9.9 23.9 46 4.1 23.9 2.9 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Baculo_PEP_C PF04513.12 EEQ29749.1 - 0.8 9.7 9.7 0.53 10.3 7.5 1.7 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.6 EEQ29749.1 - 0.86 9.0 14.3 2.1 7.7 14.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 EEQ29749.1 - 0.89 10.0 15.7 2.5 8.5 15.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) COG6 PF06419.11 EEQ29749.1 - 1.1 7.3 12.8 1.6 6.9 12.8 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 FliJ PF02050.16 EEQ29749.1 - 1.2 9.4 16.6 2.4 8.4 16.4 1.6 1 1 0 1 1 1 0 Flagellar FliJ protein Tweety PF04906.13 EEQ29749.1 - 1.2 7.7 4.2 1.8 7.2 4.2 1.1 1 0 0 1 1 1 0 Tweety APC_N_CC PF16689.5 EEQ29749.1 - 1.3 9.2 9.9 0.4 10.8 5.9 2.2 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain MCU PF04678.13 EEQ29749.1 - 1.3 9.1 8.0 3 7.9 8.0 1.7 1 0 0 1 1 1 0 Mitochondrial calcium uniporter USP8_interact PF08941.10 EEQ29749.1 - 1.5 8.6 6.3 0.18 11.6 1.8 1.7 2 0 0 2 2 1 0 USP8 interacting NleF_casp_inhib PF16809.5 EEQ29749.1 - 1.5 8.7 7.7 9.1 6.2 5.8 2.3 2 0 0 2 2 2 0 NleF caspase inhibitor OmpH PF03938.14 EEQ29749.1 - 2.1 8.7 19.0 13 6.1 19.0 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HAUS6_N PF14661.6 EEQ29749.1 - 2.4 7.7 10.4 5.6 6.5 10.4 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fib_alpha PF08702.10 EEQ29749.1 - 2.9 8.1 13.8 7.2 6.8 13.5 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 EEQ29749.1 - 3 8.2 14.1 15 5.9 14.0 2.2 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF2207 PF09972.9 EEQ29749.1 - 3.1 6.4 5.3 4.8 5.8 5.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1664 PF07889.12 EEQ29749.1 - 3.5 7.7 9.6 8.9 6.4 9.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) KxDL PF10241.9 EEQ29749.1 - 4.2 7.7 12.2 11 6.4 9.5 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein LPP PF04728.13 EEQ29749.1 - 4.7 7.7 11.6 1.6 9.2 6.8 2.8 2 1 1 3 3 2 0 Lipoprotein leucine-zipper Med9 PF07544.13 EEQ29749.1 - 6.2 7.0 15.3 23 5.2 11.8 2.9 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Fzo_mitofusin PF04799.13 EEQ29749.1 - 6.4 6.3 10.7 12 5.5 10.7 1.3 1 0 0 1 1 1 0 fzo-like conserved region Csm1_N PF18504.1 EEQ29749.1 - 6.6 7.2 17.2 0.44 10.9 6.2 3.2 1 1 1 2 2 2 0 Csm1 N-terminal domain NEMP PF10225.9 EEQ29749.1 - 6.7 6.3 4.7 11 5.6 4.7 1.3 1 0 0 1 1 1 0 NEMP family Spc24 PF08286.11 EEQ29749.1 - 9.8 6.5 12.4 2.6 8.3 6.3 2.9 1 1 1 2 2 1 0 Spc24 subunit of Ndc80 PigN PF04987.14 EEQ29750.1 - 1.8e-159 531.5 34.3 1.8e-159 531.5 34.3 1.3 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EEQ29750.1 - 1.5e-10 41.2 4.8 9.1e-09 35.4 4.6 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EEQ29750.1 - 1.8e-09 37.5 0.1 2.8e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EEQ29750.1 - 4.2e-05 23.0 0.1 8.3e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily APH PF01636.23 EEQ29751.1 - 8.5e-11 42.2 0.1 3.5e-07 30.4 0.0 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ29751.1 - 2e-07 30.8 0.0 3.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EEQ29751.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fungal_trans PF04082.18 EEQ29752.1 - 1.5e-18 66.8 0.0 5.2e-12 45.3 0.0 3.1 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ29752.1 - 0.0037 17.3 1.2 0.0072 16.4 1.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 EEQ29752.1 - 0.043 13.9 11.2 0.11 12.6 4.0 3.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FAM176 PF14851.6 EEQ29752.1 - 3 7.5 5.0 1.2 8.8 0.7 2.2 2 0 0 2 2 2 0 FAM176 family LysM PF01476.20 EEQ29753.1 - 0.00021 21.3 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 LysM domain TsaE PF02367.17 EEQ29754.1 - 0.019 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GSCFA PF08885.11 EEQ29754.1 - 0.061 13.0 0.1 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 GSCFA family KAP_NTPase PF07693.14 EEQ29754.1 - 0.087 12.1 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain adh_short PF00106.25 EEQ29756.1 - 1.2e-82 276.1 5.8 1.5e-42 145.3 0.3 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ29756.1 - 3e-64 216.8 3.7 6.4e-34 117.5 0.1 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EEQ29756.1 - 4e-33 113.6 0.0 7.7e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EEQ29756.1 - 1.1e-24 87.3 4.4 4.9e-12 46.1 0.9 2.7 2 1 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 EEQ29756.1 - 5.5e-05 22.5 0.5 0.0062 15.9 0.6 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EEQ29756.1 - 0.99 9.3 4.4 20 5.0 1.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.12 EEQ29756.1 - 3.4 7.7 5.3 19 5.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Fucokinase PF07959.12 EEQ29757.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Yip1 PF04893.17 EEQ29758.1 - 4.4e-09 36.3 8.4 8.8e-09 35.3 8.0 1.7 2 0 0 2 2 2 1 Yip1 domain DUF1282 PF06930.12 EEQ29758.1 - 0.13 12.0 4.3 0.21 11.4 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Cu-oxidase_3 PF07732.15 EEQ29759.1 - 3.7e-43 146.3 0.4 7.3e-42 142.1 0.6 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EEQ29759.1 - 3.5e-40 136.9 3.5 1.2e-35 122.2 0.1 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EEQ29759.1 - 7.8e-25 87.9 0.0 7.9e-24 84.6 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase MMR_HSR1 PF01926.23 EEQ29760.1 - 1.4e-08 34.8 2.0 1.6e-07 31.4 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EEQ29760.1 - 1.4e-07 31.0 0.0 3.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EEQ29760.1 - 0.00081 19.3 0.0 0.00081 19.3 0.0 2.1 3 0 0 3 3 3 1 RsgA GTPase Septin PF00735.18 EEQ29760.1 - 0.0024 17.2 0.0 0.0024 17.2 0.0 2.3 2 1 0 2 2 2 1 Septin FeoB_N PF02421.18 EEQ29760.1 - 0.0041 16.7 0.2 0.0097 15.4 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B NB-ARC PF00931.22 EEQ29760.1 - 0.0051 16.0 0.2 0.015 14.5 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 EEQ29760.1 - 0.0055 17.0 1.5 0.0099 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain IIGP PF05049.13 EEQ29760.1 - 0.0066 15.5 0.1 0.019 14.0 0.0 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) SRPRB PF09439.10 EEQ29760.1 - 0.011 15.2 0.0 0.011 15.2 0.0 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EEQ29760.1 - 0.021 14.9 0.0 0.021 14.9 0.0 3.8 2 2 1 3 3 2 0 Dynamin family Viral_helicase1 PF01443.18 EEQ29760.1 - 0.04 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EEQ29760.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4407 PF14362.6 EEQ29760.1 - 0.14 11.5 14.3 0.26 10.6 14.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_18 PF13238.6 EEQ29760.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.8 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.27 EEQ29760.1 - 0.23 12.0 0.0 0.23 12.0 0.0 2.6 2 1 0 2 2 1 0 ABC transporter SRP54 PF00448.22 EEQ29760.1 - 0.43 10.2 4.2 9 5.9 0.0 3.3 2 2 1 3 3 3 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 EEQ29760.1 - 0.48 10.2 5.2 0.73 9.6 0.1 2.8 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein FUSC PF04632.12 EEQ29760.1 - 1.5 7.3 3.4 2.2 6.7 3.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fzo_mitofusin PF04799.13 EEQ29760.1 - 2.5 7.7 13.5 0.19 11.3 2.7 2.7 1 1 2 3 3 3 0 fzo-like conserved region AAA_16 PF13191.6 EEQ29760.1 - 2.8 8.3 0.0 2.8 8.3 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain KfrA_N PF11740.8 EEQ29760.1 - 7.2 7.3 17.4 0.56 10.9 10.6 2.4 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term Exonuc_VII_L PF02601.15 EEQ29760.1 - 8.3 5.9 15.9 12 5.3 15.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MIP-T3_C PF17749.1 EEQ29761.1 - 0.014 15.4 3.2 0.6 10.1 0.2 2.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region ADIP PF11559.8 EEQ29761.1 - 0.021 14.9 2.8 0.041 14.0 2.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 EEQ29761.1 - 0.13 12.9 0.6 0.4 11.3 0.3 2.0 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 EEQ29761.1 - 0.27 11.3 6.7 2.3 8.4 0.1 2.5 1 1 1 2 2 2 0 Basic region leucine zipper HSP70 PF00012.20 EEQ29762.1 - 8.9e-11 40.7 0.0 1e-09 37.2 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EEQ29762.1 - 0.039 12.8 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein Ran_BP1 PF00638.18 EEQ29763.1 - 9.1e-08 32.4 0.3 2.1e-07 31.3 0.3 1.6 1 0 0 1 1 1 1 RanBP1 domain DEAD PF00270.29 EEQ29764.1 - 6.9e-25 87.8 0.0 1.1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EEQ29764.1 - 2.3e-18 66.7 0.3 1.4e-17 64.2 0.3 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EEQ29764.1 - 2.1e-13 50.6 0.1 1.8e-12 47.5 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.11 EEQ29764.1 - 0.00051 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 EEQ29764.1 - 0.00063 19.8 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Fungal_trans_2 PF11951.8 EEQ29765.1 - 3e-15 55.9 5.8 1.4e-14 53.8 5.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ29765.1 - 3.3e-05 23.9 11.5 7e-05 22.9 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 EEQ29765.1 - 0.16 12.3 3.0 0.7 10.3 3.0 2.1 1 0 0 1 1 1 0 Opy2 protein AMP-binding PF00501.28 EEQ29767.1 - 6.7e-67 225.9 0.0 9.8e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EEQ29767.1 - 4.4e-13 49.4 0.1 1.1e-12 48.1 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 EEQ29767.1 - 7.6e-11 41.3 6.9 3.1e-05 23.5 0.2 6.7 5 2 2 7 7 7 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EEQ29767.1 - 4.7e-05 23.1 17.1 0.1 12.4 0.5 5.4 4 1 1 5 5 5 3 Hexapeptide repeat of succinyl-transferase zf-RING_2 PF13639.6 EEQ29768.1 - 1.2e-12 47.9 8.2 2e-12 47.2 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EEQ29768.1 - 8e-09 35.7 6.1 1.5e-08 34.8 6.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EEQ29768.1 - 3e-07 30.2 6.5 4.8e-07 29.5 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEQ29768.1 - 1.8e-06 27.6 5.1 3.3e-06 26.7 5.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EEQ29768.1 - 6.8e-06 25.9 7.6 1.1e-05 25.2 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEQ29768.1 - 1.8e-05 24.3 5.3 3.2e-05 23.5 5.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EEQ29768.1 - 4.6e-05 23.4 1.8 9.9e-05 22.3 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EEQ29768.1 - 0.00033 20.6 5.8 0.00051 19.9 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ29768.1 - 0.0005 19.9 5.0 0.00087 19.1 5.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EEQ29768.1 - 0.0018 18.2 5.9 0.0037 17.3 5.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3H2C3 PF17122.5 EEQ29768.1 - 0.0064 16.5 1.6 0.014 15.4 1.6 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_3 PF13920.6 EEQ29768.1 - 0.008 16.0 6.4 0.013 15.3 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 EEQ29768.1 - 0.01 15.6 0.5 0.02 14.7 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 EEQ29768.1 - 0.079 13.1 8.6 0.13 12.4 8.6 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EEQ29768.1 - 0.12 12.5 6.1 0.22 11.7 6.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EEQ29768.1 - 0.31 11.4 2.2 0.64 10.4 2.2 1.5 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 EEQ29768.1 - 3.4 7.7 8.6 2.3 8.2 6.7 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ECM11 PF15463.6 EEQ29769.1 - 3.9e-37 127.8 0.2 1.6e-36 125.8 0.0 2.1 2 0 0 2 2 2 1 Extracellular mutant protein 11 UNC45-central PF11701.8 EEQ29769.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central RNA_pol_I_TF PF04090.12 EEQ29770.1 - 2.9e-05 23.7 0.0 0.017 14.6 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor bZIP_Maf PF03131.17 EEQ29771.1 - 1.1e-05 25.9 14.6 1.1e-05 25.9 14.6 3.7 3 1 1 4 4 4 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EEQ29771.1 - 0.00019 21.5 11.5 0.00019 21.5 11.5 3.5 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 EEQ29771.1 - 0.00026 21.0 14.3 0.00026 21.0 14.3 3.2 1 1 3 4 4 4 1 bZIP transcription factor DUF1062 PF06353.12 EEQ29771.1 - 0.14 13.0 9.5 0.91 10.4 8.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1062) AAA_23 PF13476.6 EEQ29771.1 - 2.2 8.7 11.1 6.3 7.2 11.1 1.8 1 0 0 1 1 1 0 AAA domain JAKMIP_CC3 PF16034.5 EEQ29771.1 - 3.1 7.7 33.4 0.18 11.7 21.9 3.1 3 0 0 3 3 3 0 JAKMIP CC3 domain Tnp_22_trimer PF17489.2 EEQ29772.1 - 0.034 14.1 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 L1 transposable element trimerization domain zf-CCCH PF00642.24 EEQ29773.1 - 2.2e-13 49.7 26.9 0.00028 20.7 1.5 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ29773.1 - 2.5e-07 30.5 28.4 0.014 15.5 0.6 5.9 5 1 0 5 5 5 4 Zinc finger domain Torus PF16131.5 EEQ29773.1 - 0.00019 22.1 20.3 0.15 12.8 1.4 4.7 1 1 3 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 EEQ29773.1 - 0.00089 19.5 12.0 0.063 13.5 0.6 3.6 2 1 1 3 3 3 3 Zinc-finger containing family zf-C3H1 PF10650.9 EEQ29773.1 - 0.29 10.9 6.7 2.2 8.1 0.0 3.8 4 0 0 4 4 4 0 Putative zinc-finger domain TFIIF_beta_N PF17683.1 EEQ29774.1 - 7.1e-32 110.9 1.1 1.3e-31 110.1 1.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EEQ29774.1 - 2.1e-27 95.0 0.4 4.2e-27 94.1 0.4 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain IHO1 PF15771.5 EEQ29774.1 - 0.12 11.2 3.0 0.15 10.8 3.0 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 PCI PF01399.27 EEQ29775.1 - 2.1e-10 41.0 0.0 5.3e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 EEQ29775.1 - 3e-08 33.6 0.1 5.4e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 NAD_binding_4 PF07993.12 EEQ29776.1 - 1.4e-30 106.4 0.0 2.9e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EEQ29776.1 - 7.5e-28 97.3 0.0 1.6e-27 96.1 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EEQ29776.1 - 7e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EEQ29776.1 - 5.9e-09 36.1 0.2 2.6e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 EEQ29776.1 - 0.042 12.9 0.0 0.37 9.9 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain p450 PF00067.22 EEQ29777.1 - 1.1e-78 265.1 0.0 1.3e-78 264.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EEQ29778.1 - 2.2e-20 72.9 0.6 6.4e-17 61.6 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ29778.1 - 8.3e-10 38.6 0.4 3.4e-06 26.8 0.2 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ29778.1 - 4e-07 30.1 0.1 6.5e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF2322 PF10084.9 EEQ29778.1 - 0.022 14.8 0.0 0.062 13.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) adh_short_C2 PF13561.6 EEQ29779.1 - 7.8e-62 208.9 1.6 2.7e-61 207.1 1.6 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ29779.1 - 6.1e-43 146.6 0.9 1e-42 145.8 0.9 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ29779.1 - 5e-10 39.6 0.3 1.1e-09 38.4 0.3 1.7 1 1 0 1 1 1 1 KR domain Zn_clus PF00172.18 EEQ29780.1 - 2e-06 27.8 7.0 2e-06 27.8 7.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ29780.1 - 6.4e-06 25.4 0.5 2.4e-05 23.5 0.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.26 EEQ29781.1 - 3.5e-79 265.9 0.2 1.5e-78 263.9 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EEQ29781.1 - 1.6e-64 218.5 0.0 2.9e-64 217.6 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EEQ29781.1 - 1e-61 208.0 0.0 3.8e-61 206.1 0.0 2.1 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EEQ29781.1 - 1.3e-41 141.3 0.4 3.4e-41 139.9 0.4 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EEQ29781.1 - 2.2e-14 53.9 0.0 4.8e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EEQ29781.1 - 7.3e-12 45.5 0.0 1.7e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 EEQ29781.1 - 3.7e-10 39.5 0.1 1.1e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EEQ29781.1 - 2.3e-05 23.9 1.2 8.8e-05 22.0 1.2 2.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 EEQ29781.1 - 6.7e-05 22.4 0.0 0.0007 19.1 0.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase FbpA PF05833.11 EEQ29781.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) MFS_1 PF07690.16 EEQ29782.1 - 3.3e-23 82.2 45.8 3.3e-23 82.2 45.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.32 EEQ29783.1 - 9.4e-15 54.8 1.9 0.015 16.2 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29783.1 - 0.099 12.9 0.1 2.6 8.4 0.0 3.1 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain U3_assoc_6 PF08640.11 EEQ29783.1 - 0.16 12.1 1.2 0.39 10.8 1.2 1.7 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 FAD_binding_2 PF00890.24 EEQ29785.1 - 6.5e-82 275.8 0.4 8.5e-82 275.5 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EEQ29785.1 - 3.4e-17 62.4 0.1 7.9e-16 58.0 0.1 3.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EEQ29785.1 - 5.5e-12 45.9 0.6 1.3e-11 44.7 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EEQ29785.1 - 4.2e-10 39.6 0.9 1.4e-09 37.8 0.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ29785.1 - 1.1e-08 35.2 0.3 7.7e-08 32.5 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ29785.1 - 1.6e-08 34.1 0.2 1.7e-07 30.8 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ29785.1 - 1.2e-06 28.0 0.0 0.0075 15.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEQ29785.1 - 6.7e-06 25.1 3.4 0.0002 20.2 0.8 3.1 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EEQ29785.1 - 9.2e-05 21.7 1.4 0.026 13.6 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EEQ29785.1 - 0.00053 19.3 0.1 0.00089 18.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EEQ29785.1 - 0.00055 19.2 0.3 0.076 12.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EEQ29785.1 - 0.041 14.5 1.6 6 7.5 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase P_proprotein PF01483.20 EEQ29785.1 - 0.083 12.9 0.2 8.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Proprotein convertase P-domain MSP1_C PF07462.11 EEQ29785.1 - 0.59 8.8 1.5 1 8.0 1.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CBP_BcsO PF17037.5 EEQ29785.1 - 1.3 9.2 6.1 2.2 8.4 6.1 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Sin3a_C PF16879.5 EEQ29786.1 - 6.3e-77 259.1 0.3 6.3e-77 259.1 0.3 3.1 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 EEQ29786.1 - 3.8e-43 145.4 1.1 9.2e-18 64.1 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EEQ29786.1 - 1.9e-40 136.9 0.3 7.2e-40 135.0 0.1 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor WDCP PF15390.6 EEQ29786.1 - 2.5 6.4 4.7 4.9 5.4 4.7 1.4 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Glyco_hydro_17 PF00332.18 EEQ29788.1 - 0.015 14.9 0.1 0.079 12.5 0.1 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 MFS_1 PF07690.16 EEQ29789.1 - 2.3e-42 145.2 68.8 5e-41 140.8 67.7 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ29789.1 - 1.2e-14 53.7 29.5 2.7e-14 52.6 29.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ29789.1 - 3.2e-14 52.7 11.6 3.2e-14 52.7 11.6 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EEQ29789.1 - 1.6 6.9 16.0 0.19 10.0 4.0 2.9 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sel1 PF08238.12 EEQ29790.1 - 2.5e-36 123.3 33.5 1.5e-05 25.5 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 EEQ29790.1 - 0.014 16.0 4.1 2.9 8.7 0.2 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.15 EEQ29791.1 - 2.4e-292 970.2 0.2 2.4e-292 970.2 0.2 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EEQ29791.1 - 2.1e-12 47.4 3.9 7e-12 45.7 3.9 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EEQ29791.1 - 1.9e-09 37.8 0.0 1e-08 35.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EEQ29791.1 - 9e-05 22.0 0.1 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EEQ29791.1 - 0.0049 16.7 0.1 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Selenoprotein_S PF06936.11 EEQ29791.1 - 1.3 8.8 4.8 2.1 8.1 2.8 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) WD40 PF00400.32 EEQ29792.1 - 7.3e-05 23.5 1.9 0.0056 17.5 0.3 3.5 2 1 1 3 3 3 2 WD domain, G-beta repeat IPTL-CTERM PF18203.1 EEQ29793.1 - 0.12 12.4 1.6 6.9 6.7 0.2 2.6 2 0 0 2 2 2 0 IPTL-CTERM motif ATG22 PF11700.8 EEQ29794.1 - 5.5e-115 384.7 25.9 9.3e-115 384.0 25.9 1.4 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like DUF3810 PF12725.7 EEQ29794.1 - 8.9 5.5 7.6 5.5 6.2 0.6 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF3810) Ras PF00071.22 EEQ29795.1 - 6.2e-51 172.2 0.5 7.6e-51 171.9 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ29795.1 - 1.5e-28 99.4 0.4 2.6e-28 98.6 0.2 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ29795.1 - 1.6e-10 40.8 0.1 1.8e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ29795.1 - 4.6e-07 29.6 0.0 5.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EEQ29795.1 - 0.00084 18.8 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EEQ29795.1 - 0.083 12.8 0.2 0.18 11.7 0.1 1.5 1 1 1 2 2 2 0 RsgA GTPase Mitofilin PF09731.9 EEQ29796.1 - 1.3e-143 480.1 23.1 7e-116 388.5 19.4 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DUF2259 PF10016.9 EEQ29796.1 - 0.054 13.4 1.1 0.11 12.5 1.1 1.5 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) Pex14_N PF04695.13 EEQ29796.1 - 0.36 11.5 13.6 0.076 13.7 4.2 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4363 PF14276.6 EEQ29796.1 - 0.92 9.7 8.5 0.77 9.9 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) DUF2205 PF10224.9 EEQ29796.1 - 2.3 8.3 5.5 0.39 10.7 0.7 2.2 2 0 0 2 2 2 0 Short coiled-coil protein ATP-synt_B PF00430.18 EEQ29796.1 - 2.8 8.1 17.6 0.67 10.0 7.9 2.5 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DSBA PF01323.20 EEQ29801.1 - 1.2e-17 64.3 0.0 1.5e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Methyltransf_16 PF10294.9 EEQ29803.1 - 2.7e-43 147.7 0.0 8.4e-43 146.1 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EEQ29803.1 - 0.00027 20.8 0.0 0.00067 19.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ29803.1 - 0.0019 18.9 0.0 0.0043 17.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ29803.1 - 0.0051 16.6 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEQ29803.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EEQ29803.1 - 0.025 15.3 0.0 0.075 13.8 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain Orn_Arg_deC_N PF02784.16 EEQ29804.1 - 9.6e-84 280.6 0.0 2e-83 279.5 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EEQ29804.1 - 4.7e-18 65.2 0.0 6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EEQ29804.1 - 0.0012 18.4 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel cobW PF02492.19 EEQ29805.1 - 7.5e-41 139.6 0.0 1.2e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EEQ29805.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.7 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 EEQ29805.1 - 0.0039 17.1 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 EEQ29805.1 - 0.013 15.2 0.1 0.37 10.6 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ29805.1 - 0.096 13.0 0.0 0.24 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EEQ29805.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EEQ29805.1 - 0.52 10.8 1.7 1.1 9.8 1.7 1.4 1 0 0 1 1 1 0 AAA domain SET PF00856.28 EEQ29806.1 - 0.0048 17.3 1.3 0.043 14.2 1.1 2.2 2 1 0 2 2 2 1 SET domain MFS_1 PF07690.16 EEQ29807.1 - 6.7e-33 114.1 28.0 6.7e-33 114.1 28.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DHHC PF01529.20 EEQ29808.1 - 8.7e-33 113.3 4.4 8.7e-33 113.3 4.4 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Acetyltransf_3 PF13302.7 EEQ29809.1 - 4e-26 92.3 0.0 7.8e-26 91.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ29809.1 - 6.6e-06 26.3 0.0 9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PBAN PF05874.11 EEQ29809.1 - 5.8e-05 23.1 0.0 8.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Pheromone biosynthesis activating neuropeptide (PBAN) Acetyltransf_8 PF13523.6 EEQ29809.1 - 0.00023 20.8 0.1 0.00066 19.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FeoB_Cyto PF17910.1 EEQ29809.1 - 0.074 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 FeoB cytosolic helical domain Pkinase PF00069.25 EEQ29810.1 - 1.1e-70 238.1 0.0 1.9e-70 237.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29810.1 - 3.5e-44 151.0 0.0 5.9e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EEQ29810.1 - 1e-05 25.6 0.0 0.058 13.6 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EEQ29810.1 - 4.1e-05 23.0 0.0 6.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ29810.1 - 0.02 13.7 0.0 0.062 12.1 0.0 1.8 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EEQ29810.1 - 0.042 12.8 0.1 0.075 12.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EEQ29810.1 - 0.053 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tau95 PF09734.9 EEQ29810.1 - 0.15 12.8 0.9 0.48 11.2 0.9 1.8 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain OPA3 PF07047.12 EEQ29811.1 - 2.8e-48 162.8 1.9 3.8e-48 162.4 1.9 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.9 EEQ29811.1 - 0.0012 19.3 0.3 0.0025 18.3 0.3 1.6 1 0 0 1 1 1 1 Mediator complex protein Myosin_head PF00063.21 EEQ29812.1 - 1.6e-241 803.3 4.9 1.9e-241 803.1 4.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EEQ29812.1 - 7.4e-50 169.2 0.0 1.3e-49 168.4 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EEQ29812.1 - 8.9e-12 44.4 0.0 1.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EEQ29812.1 - 7.3e-08 32.0 0.0 2e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EEQ29812.1 - 7.7e-08 32.1 0.0 3e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain AAA_22 PF13401.6 EEQ29812.1 - 0.014 15.7 0.0 0.041 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ29812.1 - 0.016 15.6 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 EEQ29812.1 - 0.016 14.7 0.5 3.4 7.2 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain IQ PF00612.27 EEQ29812.1 - 0.03 14.1 9.7 1.1 9.3 1.0 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif TrwB_AAD_bind PF10412.9 EEQ29812.1 - 0.15 10.9 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 EEQ29812.1 - 0.18 11.7 0.0 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RSN1_TM PF13967.6 EEQ29813.1 - 0.22 11.3 0.5 0.42 10.4 0.5 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport p450 PF00067.22 EEQ29815.1 - 1.2e-55 189.1 0.0 3.8e-46 157.8 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 ABC_membrane PF00664.23 EEQ29817.1 - 2.4e-91 306.2 28.8 2.9e-47 161.6 10.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ29817.1 - 7.2e-60 201.5 0.0 2.1e-28 99.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ29817.1 - 3e-15 56.3 5.6 1.7e-05 24.4 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ29817.1 - 2e-08 33.9 1.1 0.0037 17.0 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EEQ29817.1 - 1.5e-07 31.6 2.5 0.6 9.9 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EEQ29817.1 - 5.1e-07 30.2 0.2 0.013 15.9 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EEQ29817.1 - 5.6e-07 29.9 1.6 0.033 14.5 0.0 4.3 4 1 0 4 4 3 2 AAA domain AAA_23 PF13476.6 EEQ29817.1 - 3.1e-06 27.9 0.2 0.002 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EEQ29817.1 - 5e-06 26.5 0.1 0.19 11.6 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_25 PF13481.6 EEQ29817.1 - 2.4e-05 24.0 0.0 0.47 10.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EEQ29817.1 - 4.3e-05 24.1 0.0 0.29 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EEQ29817.1 - 0.00039 20.2 2.7 0.49 10.1 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 EEQ29817.1 - 0.0015 17.4 1.1 0.15 10.8 0.4 3.2 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 EEQ29817.1 - 0.0017 18.5 0.1 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EEQ29817.1 - 0.0033 17.2 0.5 1.1 9.0 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA PF00004.29 EEQ29817.1 - 0.0036 17.7 0.0 0.16 12.4 0.0 3.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EEQ29817.1 - 0.0041 17.2 0.3 1.1 9.3 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.14 EEQ29817.1 - 0.0065 16.5 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EEQ29817.1 - 0.0094 15.7 1.6 7.7 6.2 0.0 3.7 3 1 0 3 3 3 0 AAA domain DUF3987 PF13148.6 EEQ29817.1 - 0.0096 15.0 0.3 3.4 6.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_24 PF13479.6 EEQ29817.1 - 0.012 15.4 1.0 1.7 8.3 0.4 3.0 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 EEQ29817.1 - 0.019 14.1 0.0 0.36 9.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 EEQ29817.1 - 0.02 15.2 0.2 14 6.2 0.0 2.8 3 0 0 3 3 2 0 RNA helicase DUF87 PF01935.17 EEQ29817.1 - 0.021 15.0 2.0 0.74 9.9 0.1 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain APS_kinase PF01583.20 EEQ29817.1 - 0.025 14.5 0.1 8.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_7 PF12775.7 EEQ29817.1 - 0.068 12.7 0.0 9.2 5.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 EEQ29817.1 - 0.11 11.8 4.5 7.6 5.8 0.0 3.5 3 0 0 3 3 3 0 KaiC FtsK_SpoIIIE PF01580.18 EEQ29817.1 - 0.15 11.4 0.0 18 4.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.6 EEQ29817.1 - 0.17 12.2 1.1 14 6.0 0.0 3.4 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Cytidylate_kin PF02224.18 EEQ29817.1 - 0.28 10.9 2.0 1.7 8.3 0.2 2.5 3 0 0 3 3 2 0 Cytidylate kinase MFS_1 PF07690.16 EEQ29818.1 - 1.5e-28 99.8 43.0 1.5e-28 99.8 43.0 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 EEQ29819.1 - 6.5e-46 157.0 0.0 8.7e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Bacteroid_pep PF14406.6 EEQ29819.1 - 0.12 12.8 0.2 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes Ric8 PF10165.9 EEQ29821.1 - 3.6e-121 405.4 0.0 4.4e-121 405.1 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Polysacc_synt_4 PF04669.13 EEQ29822.1 - 1.1e-18 67.5 0.9 3.4e-17 62.6 0.8 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis Sugar_tr PF00083.24 EEQ29823.1 - 2.2e-138 461.9 19.4 2.6e-138 461.7 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ29823.1 - 4.3e-25 88.4 34.8 1.3e-22 80.2 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 EEQ29823.1 - 0.00013 20.3 0.6 0.22 9.7 0.0 2.3 2 0 0 2 2 2 2 BT1 family MFS_1_like PF12832.7 EEQ29823.1 - 0.0021 17.0 13.3 0.056 12.3 0.4 2.4 1 1 1 2 2 2 2 MFS_1 like family Pox_A14 PF05767.12 EEQ29823.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.1 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 Pkinase PF00069.25 EEQ29824.1 - 3e-11 43.2 0.0 4.4e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EEQ29824.1 - 2.8e-05 24.2 0.7 0.00034 20.6 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEQ29824.1 - 0.00013 21.4 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EEQ29824.1 - 0.00079 18.8 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EEQ29824.1 - 0.0032 17.0 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 EEQ29824.1 - 0.032 13.8 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EEQ29824.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DPPIV_rep PF18811.1 EEQ29824.1 - 0.14 12.1 1.1 0.31 11.1 1.1 1.6 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region Glyco_hydro_25 PF01183.20 EEQ29826.1 - 6e-41 140.6 0.4 7e-41 140.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Rif1_N PF12231.8 EEQ29827.1 - 5.8e-127 423.8 0.1 9.9e-127 423.0 0.1 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal UPF0561 PF10573.9 EEQ29827.1 - 0.25 11.5 2.4 0.73 10.0 2.4 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Aldose_epim PF01263.20 EEQ29828.1 - 1.3e-42 146.2 0.0 1.5e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase MFS_1 PF07690.16 EEQ29829.1 - 2.3e-25 89.3 25.0 2.3e-25 89.3 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pmp3 PF01679.17 EEQ29830.1 - 0.33 11.2 0.7 0.47 10.7 0.7 1.2 1 0 0 1 1 1 0 Proteolipid membrane potential modulator DAHP_synth_2 PF01474.16 EEQ29831.1 - 6.5e-205 680.7 0.0 7.3e-205 680.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family PLA2_B PF01735.18 EEQ29833.1 - 6.7e-193 641.6 1.2 7.7e-193 641.4 1.2 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Choline_transpo PF04515.12 EEQ29834.1 - 3.7e-82 276.1 18.6 3.7e-82 276.1 18.6 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter ABM PF03992.16 EEQ29835.1 - 0.12 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase NAD_binding_1 PF00175.21 EEQ29836.1 - 3.6e-10 40.5 0.0 5.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEQ29836.1 - 1.2e-09 38.4 0.0 4.7e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EEQ29836.1 - 0.0053 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain p450 PF00067.22 EEQ29837.1 - 0.012 14.4 0.1 0.046 12.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome P450 Hyr1 PF15789.5 EEQ29837.1 - 0.077 12.6 1.4 0.089 12.4 0.4 1.5 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 adh_short_C2 PF13561.6 EEQ29839.1 - 9.7e-54 182.4 1.1 2.3e-27 96.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ29839.1 - 2.7e-46 157.5 2.4 2.8e-32 111.8 1.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EEQ29839.1 - 2.9e-14 53.4 0.5 4.2e-14 52.9 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EEQ29839.1 - 0.00059 19.8 0.0 0.005 16.7 0.0 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EEQ29839.1 - 0.0026 17.2 0.1 0.0042 16.5 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EEQ29839.1 - 0.018 14.5 0.6 0.028 13.9 0.6 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GGACT PF06094.12 EEQ29840.1 - 1e-14 55.2 0.3 1.2e-14 54.9 0.3 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Piwi PF02171.17 EEQ29841.1 - 2.9e-75 253.3 0.0 4.1e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EEQ29841.1 - 2.2e-19 70.5 0.0 4.1e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EEQ29841.1 - 1.2e-13 50.5 0.1 3.8e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EEQ29841.1 - 4.5e-10 39.5 0.0 1.5e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 PAZ domain ArgoL2 PF16488.5 EEQ29841.1 - 2.4e-05 24.6 0.6 8.4e-05 22.8 0.1 2.3 3 0 0 3 3 3 1 Argonaute linker 2 domain ArgoMid PF16487.5 EEQ29841.1 - 0.02 15.2 0.0 0.056 13.7 0.0 1.8 1 0 0 1 1 1 0 Mid domain of argonaute Ribophorin_II PF05817.14 EEQ29843.1 - 6.5e-31 107.6 0.1 7.4e-31 107.4 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PufQ PF05398.11 EEQ29843.1 - 0.14 12.3 1.4 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 PufQ cytochrome subunit DUF4527 PF15030.6 EEQ29844.1 - 0.055 12.9 3.2 0.074 12.5 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) EVE PF01878.18 EEQ29846.1 - 1.1e-50 171.5 0.1 2.4e-50 170.3 0.1 1.6 1 0 0 1 1 1 1 EVE domain DUF2020 PF09449.10 EEQ29846.1 - 0.074 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) Methyltransf_PK PF05891.12 EEQ29847.1 - 3e-52 177.3 0.0 6.5e-52 176.2 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 EEQ29847.1 - 5.1e-05 22.7 0.1 0.0001 21.7 0.1 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EEQ29847.1 - 0.00082 20.0 0.0 0.002 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ29847.1 - 0.0088 16.7 0.0 0.021 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Aldedh PF00171.22 EEQ29848.1 - 9.2e-164 545.3 6.3 1.6e-107 359.9 0.5 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family bZIP_2 PF07716.15 EEQ29850.1 - 7.8e-05 22.7 8.7 0.00014 21.9 8.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DUF2188 PF09954.9 EEQ29850.1 - 0.12 12.6 1.1 0.27 11.4 1.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) bZIP_1 PF00170.21 EEQ29850.1 - 0.28 11.3 5.9 0.62 10.2 5.9 1.5 1 0 0 1 1 1 0 bZIP transcription factor His_Phos_2 PF00328.22 EEQ29851.1 - 2.2e-62 211.6 0.0 2.5e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AhpC-TSA PF00578.21 EEQ29852.1 - 2.9e-30 104.7 0.0 4.2e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EEQ29852.1 - 7.7e-16 58.1 0.0 1.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EEQ29852.1 - 2.5e-08 33.6 0.0 4.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_3 PF13415.6 EEQ29853.1 - 6.4e-17 61.4 8.9 3.6e-10 39.9 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EEQ29853.1 - 6.1e-14 51.8 1.0 0.00021 21.2 0.1 5.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EEQ29853.1 - 5.2e-13 48.8 0.7 0.07 13.4 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EEQ29853.1 - 2.3e-11 43.1 0.2 0.032 13.8 0.0 4.3 4 1 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 EEQ29853.1 - 3.3e-09 36.5 2.0 0.009 16.0 0.0 4.2 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 EEQ29853.1 - 2.8e-06 27.1 4.7 0.0028 17.6 0.0 5.0 5 0 0 5 5 5 1 Kelch motif mRNA_triPase PF02940.15 EEQ29854.1 - 1.2e-55 188.6 0.0 2e-55 187.9 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain WD40 PF00400.32 EEQ29855.1 - 3.9e-14 52.8 3.8 0.00013 22.7 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Spc7_N PF15402.6 EEQ29855.1 - 1 7.5 23.4 1.6 6.9 0.3 2.1 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 CTP_transf_like PF01467.26 EEQ29856.1 - 0.0069 16.6 1.8 0.089 13.0 1.8 2.2 1 1 0 1 1 1 1 Cytidylyltransferase-like F-box PF00646.33 EEQ29857.1 - 0.29 11.1 0.1 0.29 11.1 0.1 3.2 3 0 0 3 3 3 0 F-box domain Fungal_trans_2 PF11951.8 EEQ29858.1 - 0.00013 20.9 0.3 0.00021 20.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UbiA PF01040.18 EEQ29859.1 - 9.4e-56 188.9 17.5 9.4e-56 188.9 17.5 1.7 2 0 0 2 2 2 1 UbiA prenyltransferase family PQ-loop PF04193.14 EEQ29860.1 - 1.1e-19 69.9 7.0 4.1e-12 45.7 1.4 2.9 2 0 0 2 2 2 2 PQ loop repeat Med8 PF10232.9 EEQ29861.1 - 6.5e-60 202.6 0.7 9.5e-60 202.1 0.7 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 TMEM154 PF15102.6 EEQ29862.1 - 0.0058 16.5 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Insulin_TMD PF17870.1 EEQ29862.1 - 0.047 13.8 0.4 0.09 12.9 0.4 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 EEQ29862.1 - 0.13 13.2 0.0 0.26 12.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Abhydrolase_1 PF00561.20 EEQ29867.1 - 6.9e-05 22.6 0.0 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ29867.1 - 0.0011 18.5 0.1 0.056 12.9 0.0 2.8 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EEQ29867.1 - 0.009 16.6 0.0 0.03 14.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family TMF_TATA_bd PF12325.8 EEQ29868.1 - 0.0049 17.1 1.7 0.0049 17.1 1.7 4.0 3 2 0 3 3 3 1 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.11 EEQ29868.1 - 0.028 14.2 3.9 0.2 11.4 0.9 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Phlebovirus_NSM PF07246.11 EEQ29868.1 - 0.035 13.5 6.2 0.15 11.4 2.0 2.3 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M JIP_LZII PF16471.5 EEQ29868.1 - 0.073 13.2 0.4 0.073 13.2 0.4 3.7 4 1 0 4 4 3 0 JNK-interacting protein leucine zipper II TMPIT PF07851.13 EEQ29868.1 - 0.47 9.6 5.5 15 4.7 3.9 2.4 2 0 0 2 2 2 0 TMPIT-like protein Sec34 PF04136.15 EEQ29868.1 - 0.48 10.3 7.1 1.9 8.4 0.5 3.2 3 2 0 3 3 3 0 Sec34-like family Tropomyosin_1 PF12718.7 EEQ29868.1 - 0.54 10.4 14.9 0.047 13.9 3.5 2.9 2 1 0 2 2 2 0 Tropomyosin like Med21 PF11221.8 EEQ29868.1 - 0.78 10.0 17.1 0.08 13.2 2.9 3.9 2 2 0 2 2 2 0 Subunit 21 of Mediator complex DUF1664 PF07889.12 EEQ29868.1 - 1.2 9.2 6.7 2.6 8.1 1.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Streptin-Immun PF11083.8 EEQ29868.1 - 2.3 8.7 5.9 11 6.5 0.1 3.4 4 1 0 4 4 4 0 Lantibiotic streptin immunity protein AAA_13 PF13166.6 EEQ29868.1 - 3.5 6.1 10.5 0.53 8.9 4.7 2.2 2 1 0 2 2 2 0 AAA domain DUF5320 PF17253.2 EEQ29868.1 - 4.1 8.5 5.3 4.4 8.4 0.1 3.2 3 1 1 4 4 4 0 Family of unknown function (DUF5320) Fez1 PF06818.15 EEQ29868.1 - 5.2 7.5 16.2 11 6.4 0.9 2.6 2 1 0 2 2 2 0 Fez1 HIP1_clath_bdg PF16515.5 EEQ29868.1 - 9.2 7.0 20.8 1.4 9.5 3.4 4.6 3 2 2 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pkinase PF00069.25 EEQ29869.1 - 1.9e-23 83.2 0.0 4.6e-23 81.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29869.1 - 1.5e-09 37.5 0.0 7.7e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EEQ29869.1 - 0.16 11.3 0.2 0.24 10.8 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPN2_C PF18004.1 EEQ29870.1 - 2.4e-58 196.6 8.6 2.4e-58 196.6 8.6 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EEQ29870.1 - 1.7e-32 110.2 25.1 7.6e-10 38.7 0.0 8.8 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EEQ29870.1 - 2.3e-22 79.1 0.5 6.6e-16 58.5 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EEQ29870.1 - 4.3e-09 36.7 0.1 0.019 15.5 0.0 4.3 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 EEQ29870.1 - 3.6e-06 26.8 0.1 1.8 9.0 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EEQ29870.1 - 0.0015 18.6 0.0 0.099 12.7 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EEQ29870.1 - 0.0077 16.8 2.0 1.1 10.2 0.0 3.8 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Phage_TAC_12 PF12363.8 EEQ29870.1 - 0.11 12.9 0.2 0.55 10.7 0.1 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Acyl-CoA_dh_1 PF00441.24 EEQ29871.1 - 6.5e-42 143.3 0.2 9.7e-42 142.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EEQ29871.1 - 2.1e-21 75.9 0.1 3.4e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EEQ29871.1 - 1.1e-20 74.3 0.0 2.4e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 EEQ29871.1 - 1.4e-14 54.0 0.6 2.9e-14 53.0 0.6 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 EEQ29871.1 - 2e-09 37.8 0.0 3.4e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spt5-NGN PF03439.13 EEQ29872.1 - 7.8e-23 80.2 0.0 1.3e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 EEQ29872.1 - 4.4e-19 68.8 19.2 4.4e-19 68.8 19.2 3.9 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 EEQ29872.1 - 5.3e-18 65.8 11.9 5.3e-18 65.8 11.9 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EEQ29872.1 - 8.2e-09 35.1 17.7 0.0032 17.3 1.6 4.9 4 0 0 4 4 4 3 KOW motif DUF3912 PF13051.6 EEQ29872.1 - 0.00051 20.3 9.0 0.0039 17.4 0.1 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3912) DUF1506 PF07405.11 EEQ29872.1 - 0.24 11.6 0.2 0.85 9.8 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1506) CS PF04969.16 EEQ29873.1 - 9.5e-17 61.8 0.1 1.9e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 CS domain Pkinase PF00069.25 EEQ29874.1 - 8.8e-19 67.9 0.1 8.2e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29874.1 - 3.9e-05 23.1 0.8 0.054 12.8 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Anoctamin PF04547.12 EEQ29875.1 - 1.4e-111 373.6 5.2 1.7e-111 373.3 5.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Pex2_Pex12 PF04757.14 EEQ29875.1 - 0.12 11.9 1.5 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region bZIP_1 PF00170.21 EEQ29876.1 - 1.6e-07 31.3 9.4 8.7e-07 29.0 9.4 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EEQ29876.1 - 0.24 11.5 11.2 5.9 7.0 10.5 3.0 2 1 0 2 2 2 0 Basic region leucine zipper DUF5336 PF17270.2 EEQ29876.1 - 1 9.0 11.0 0.042 13.5 4.9 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5336) API5 PF05918.11 EEQ29876.1 - 2.4 6.9 9.6 0.25 10.1 4.7 1.7 1 1 1 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Actin PF00022.19 EEQ29877.1 - 3.3e-44 151.1 0.0 7.7e-23 80.8 0.0 3.4 1 1 1 2 2 2 2 Actin DASH_Dad4 PF08650.10 EEQ29878.1 - 2.2e-15 56.4 2.5 3.6e-15 55.7 2.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 EEQ29878.1 - 0.13 12.5 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor YL1_C PF08265.11 EEQ29879.1 - 6.9e-16 57.7 0.2 1.1e-15 57.1 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.12 EEQ29880.1 - 8.3e-13 48.8 6.1 1.1e-12 48.4 6.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Profilin PF00235.19 EEQ29881.1 - 6.5e-43 146.0 0.0 7.5e-43 145.8 0.0 1.0 1 0 0 1 1 1 1 Profilin SSP160 PF06933.11 EEQ29882.1 - 1.4 7.0 11.8 2.8 6.0 11.8 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EEQ29882.1 - 4.2 7.4 19.0 0.78 9.7 13.0 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.12 EEQ29882.1 - 8.9 4.1 6.0 16 3.3 6.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sec63 PF02889.16 EEQ29883.1 - 5.4e-129 428.8 0.0 3.3e-77 259.1 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EEQ29883.1 - 2.5e-53 180.4 0.7 2.1e-26 92.8 0.8 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EEQ29883.1 - 5e-23 82.0 0.0 3.9e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ29883.1 - 5.8e-16 58.8 0.1 4.7e-07 30.1 0.0 4.5 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EEQ29883.1 - 2.3e-07 31.2 0.2 0.014 15.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EEQ29883.1 - 2.7e-07 30.5 0.2 0.0019 18.0 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EEQ29883.1 - 2.3e-05 24.8 1.1 0.0022 18.4 0.7 2.7 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 EEQ29883.1 - 0.0045 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal helicase PWI domain PhoH PF02562.16 EEQ29883.1 - 0.0095 15.4 0.0 0.63 9.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EEQ29883.1 - 0.018 14.1 0.0 2.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 EEQ29883.1 - 0.03 13.7 0.5 17 4.8 0.1 3.7 4 0 0 4 4 4 0 Bacterial TniB protein AAA_7 PF12775.7 EEQ29883.1 - 0.033 13.7 0.1 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EEQ29883.1 - 0.075 12.8 0.1 4.7 6.9 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein DEK_C PF08766.11 EEQ29883.1 - 0.11 12.4 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 DEK C terminal domain TetR_C_19 PF17924.1 EEQ29884.1 - 0.12 13.0 0.1 1.5 9.4 0.1 2.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Cupin_1 PF00190.22 EEQ29886.1 - 3.7e-36 124.0 0.0 2.5e-17 62.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EEQ29886.1 - 9.9e-21 73.2 0.9 5.7e-10 38.8 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EEQ29886.1 - 1.5e-05 24.6 0.3 0.011 15.4 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EEQ29886.1 - 2.4e-05 24.3 0.8 0.019 14.9 0.2 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Ectoine_synth PF06339.12 EEQ29886.1 - 0.11 12.7 0.1 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Ectoine synthase A2L_zn_ribbon PF08792.10 EEQ29888.1 - 0.23 11.2 3.4 0.38 10.5 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Synaptobrevin PF00957.21 EEQ29889.1 - 8.9e-14 51.1 0.2 1.3e-13 50.5 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EEQ29889.1 - 7.5e-11 41.9 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain MFS_1 PF07690.16 EEQ29890.1 - 1.2e-25 90.3 68.0 1.5e-19 70.2 44.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ29890.1 - 1.8e-05 23.5 21.5 0.00037 19.2 9.0 3.1 1 1 2 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 EEQ29890.1 - 0.083 12.2 33.3 0.12 11.6 0.7 3.2 1 1 2 3 3 3 0 Uncharacterised MFS-type transporter YbfB Ras PF00071.22 EEQ29891.1 - 6.4e-29 100.6 0.0 1.1e-27 96.7 0.0 2.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EEQ29891.1 - 1.4e-22 80.2 0.0 2.7e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ29891.1 - 2e-08 33.9 0.0 3.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 EEQ29891.1 - 0.0003 21.2 0.1 0.00097 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EEQ29891.1 - 0.0049 16.9 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.14 EEQ29891.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EEQ29891.1 - 0.052 13.4 0.1 0.15 11.9 0.1 1.8 2 1 1 3 3 3 0 RsgA GTPase PduV-EutP PF10662.9 EEQ29891.1 - 0.074 12.8 0.0 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EEQ29891.1 - 0.076 13.3 1.3 0.19 12.0 0.1 2.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EEQ29891.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain FMN_dh PF01070.18 EEQ29892.1 - 1.5e-120 402.4 0.1 1.8e-120 402.1 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EEQ29892.1 - 5.3e-21 74.6 0.0 1.1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EEQ29892.1 - 3.6e-07 29.6 0.1 5.7e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EEQ29892.1 - 3.1e-06 26.8 0.0 5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EEQ29892.1 - 0.00018 20.7 2.1 0.00044 19.4 0.2 2.5 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EEQ29892.1 - 0.031 13.7 0.8 1.1 8.6 0.1 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 EEQ29892.1 - 0.083 12.2 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Metallophos PF00149.28 EEQ29893.1 - 9.9e-14 52.3 3.2 1.4e-13 51.9 3.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEQ29893.1 - 5.4e-07 29.9 0.5 1.1e-05 25.7 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.6 EEQ29893.1 - 0.0018 17.0 0.0 0.0024 16.6 0.0 1.1 1 0 0 1 1 1 1 MutL protein Pkinase PF00069.25 EEQ29894.1 - 4.2e-40 137.8 0.0 7.9e-23 81.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29894.1 - 3.8e-13 49.3 0.1 1.3e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ29894.1 - 0.043 12.6 0.0 0.067 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Bud13 PF09736.9 EEQ29895.1 - 2.4e-48 164.2 0.9 2.4e-48 164.2 0.9 3.1 2 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Nop16 PF09420.10 EEQ29895.1 - 0.36 10.8 11.0 0.064 13.3 6.2 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 DUF812 PF05667.11 EEQ29896.1 - 0.027 13.4 0.5 0.032 13.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Macoilin PF09726.9 EEQ29896.1 - 0.039 12.5 0.3 0.049 12.2 0.3 1.1 1 0 0 1 1 1 0 Macoilin family Phage_GP20 PF06810.11 EEQ29896.1 - 0.082 12.7 0.2 0.16 11.7 0.1 1.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF745 PF05335.13 EEQ29896.1 - 0.093 12.4 1.4 0.17 11.6 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PEP-utilisers_N PF05524.13 EEQ29896.1 - 0.094 12.9 0.3 0.16 12.2 0.3 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal PhoU PF01895.19 EEQ29896.1 - 0.14 12.6 0.1 0.35 11.4 0.1 1.6 1 0 0 1 1 1 0 PhoU domain Prefoldin_2 PF01920.20 EEQ29896.1 - 0.5 10.3 3.1 1 9.3 3.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit FlaC_arch PF05377.11 EEQ29896.1 - 0.9 10.0 3.7 0.53 10.7 0.7 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DNA_binding_1 PF01035.20 EEQ29897.1 - 9.9e-26 89.7 0.0 1.3e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PHINT_rpt PF14882.6 EEQ29897.1 - 0.077 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Phage-integrase repeat unit Fungal_trans_2 PF11951.8 EEQ29899.1 - 4.1e-102 341.9 5.9 4.6e-102 341.7 5.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Brr6_like_C_C PF10104.9 EEQ29900.1 - 2.2e-47 160.2 0.9 2.9e-47 159.8 0.9 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain AA_permease PF00324.21 EEQ29901.1 - 8e-120 400.6 45.6 9.1e-120 400.5 45.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ29901.1 - 2e-26 92.8 49.7 2.5e-26 92.5 49.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ29902.1 - 1.1e-48 166.1 44.2 2.6e-48 164.9 44.2 1.5 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 EEQ29903.1 - 7.3e-15 55.0 0.0 3.7e-10 39.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29903.1 - 0.00092 18.6 0.0 0.0032 16.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase polyprenyl_synt PF00348.17 EEQ29904.1 - 2.9e-42 144.5 0.0 4.6e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 EEQ29904.1 - 0.00016 21.1 0.1 0.1 11.9 0.0 2.3 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain DUF459 PF04311.13 EEQ29904.1 - 0.0026 16.8 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF459) Translin PF01997.16 EEQ29904.1 - 0.005 16.9 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Translin family ANTAR PF03861.14 EEQ29904.1 - 0.0057 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 ANTAR domain Peptidase_M20 PF01546.28 EEQ29905.1 - 1.7e-05 24.6 0.1 3.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEQ29905.1 - 0.034 14.1 0.1 0.097 12.6 0.1 1.8 1 1 0 1 1 1 0 Peptidase dimerisation domain HNH_2 PF13391.6 EEQ29906.1 - 2e-14 53.5 0.0 3.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Acetyltransf_1 PF00583.25 EEQ29908.1 - 1.5e-16 60.7 0.0 3.4e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GRIP PF01465.20 EEQ29908.1 - 5.6e-15 55.0 0.3 1.3e-14 53.8 0.3 1.7 1 0 0 1 1 1 1 GRIP domain Acetyltransf_7 PF13508.7 EEQ29908.1 - 4.8e-07 30.1 0.0 9.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ29908.1 - 8e-07 28.9 0.0 2.7e-06 27.2 0.0 1.9 2 0 0 2 2 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EEQ29908.1 - 6e-06 27.0 0.0 2.2e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ29908.1 - 5.6e-05 23.1 0.0 0.00018 21.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CALCOCO1 PF07888.11 EEQ29908.1 - 7.1e-05 21.9 139.2 0.006 15.5 23.7 6.6 3 2 3 6 6 6 4 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 EEQ29908.1 - 0.0007 19.9 144.6 0.12 12.6 16.7 9.6 4 3 2 7 7 6 2 Autophagy protein 16 (ATG16) Leu_zip PF15294.6 EEQ29908.1 - 0.00078 19.0 19.1 0.00078 19.0 19.1 7.7 3 2 3 7 7 7 1 Leucine zipper Spc7 PF08317.11 EEQ29908.1 - 0.0046 15.9 15.1 0.0046 15.9 15.1 7.9 3 2 4 7 7 7 3 Spc7 kinetochore protein Uso1_p115_C PF04871.13 EEQ29908.1 - 0.0077 16.6 13.0 0.0077 16.6 13.0 10.7 4 2 7 11 11 10 1 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 EEQ29908.1 - 0.011 15.8 15.9 0.011 15.8 15.9 9.4 4 2 5 10 10 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 EEQ29908.1 - 0.011 15.8 13.8 0.011 15.8 13.8 11.4 4 2 7 11 11 10 0 Designed helical repeat protein 10 domain Yuri_gagarin PF15934.5 EEQ29908.1 - 0.021 14.7 0.5 0.021 14.7 0.5 6.4 2 2 5 7 7 5 0 Yuri gagarin GAS PF13851.6 EEQ29908.1 - 0.034 13.5 126.3 0.036 13.4 21.2 8.2 3 2 3 7 7 7 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 EEQ29908.1 - 0.047 13.7 38.3 2.3 8.3 4.7 7.1 4 2 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bap31_Bap29_C PF18035.1 EEQ29908.1 - 0.054 13.5 0.1 0.054 13.5 0.1 9.7 10 1 0 10 10 10 0 Bap31/Bap29 cytoplasmic coiled-coil domain Filament PF00038.21 EEQ29908.1 - 0.079 12.5 119.3 0.098 12.2 49.2 6.2 3 2 1 5 5 5 0 Intermediate filament protein VGPC1_C PF16799.5 EEQ29908.1 - 0.14 12.1 0.1 0.14 12.1 0.1 4.2 4 0 0 4 4 4 0 C-terminal membrane-localisation domain of ion-channel, VCN1 TFA2_Winged_2 PF18121.1 EEQ29908.1 - 0.3 10.8 3.8 20 5.0 0.4 4.3 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Fez1 PF06818.15 EEQ29908.1 - 5.2 7.5 130.5 3.7 8.0 10.9 8.3 2 1 7 9 9 9 0 Fez1 HMMR_N PF15905.5 EEQ29908.1 - 7.5 5.9 133.0 0.2 11.1 15.3 7.8 3 2 3 7 7 7 0 Hyaluronan mediated motility receptor N-terminal zinc_ribbon_10 PF10058.9 EEQ29909.1 - 1.5e-18 66.2 0.1 2.4e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein cNMP_binding PF00027.29 EEQ29910.1 - 1.4e-30 105.2 3.0 4.1e-20 71.7 0.0 5.5 6 0 0 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 EEQ29910.1 - 1.1e-16 61.7 11.6 6e-16 59.2 7.4 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase DAO PF01266.24 EEQ29911.1 - 5.1e-24 85.5 0.0 6.3e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EEQ29911.1 - 0.00023 21.2 0.0 0.0068 16.4 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EEQ29911.1 - 0.00048 20.4 0.0 0.002 18.4 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 EEQ29911.1 - 0.0011 19.1 0.0 0.0039 17.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EEQ29911.1 - 0.002 18.4 0.0 0.0048 17.2 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain K_oxygenase PF13434.6 EEQ29911.1 - 0.0092 15.2 0.0 0.027 13.6 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EEQ29911.1 - 0.033 13.4 0.0 0.56 9.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EEQ29911.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family Methyltransf_33 PF10017.9 EEQ29912.1 - 6.9e-63 212.6 0.0 9.6e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Fungal_trans_2 PF11951.8 EEQ29913.1 - 1.3e-18 67.0 0.1 3e-17 62.5 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EEQ29915.1 - 0.25 11.9 10.2 1.8 9.2 0.5 2.8 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ29915.1 - 0.63 11.0 6.5 1.8 9.6 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger ATP-synt_Eps PF04627.13 EEQ29917.1 - 0.029 14.4 0.2 0.074 13.0 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain p450 PF00067.22 EEQ29918.1 - 1.7e-56 191.9 0.0 1.4e-45 155.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 SF3A3 PF16837.5 EEQ29918.1 - 0.89 10.1 3.3 1.8 9.1 0.1 3.0 4 0 0 4 4 4 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 ISN1 PF06437.11 EEQ29919.1 - 4.4e-176 585.8 0.1 2.9e-170 566.6 0.0 2.0 1 1 1 2 2 2 2 IMP-specific 5'-nucleotidase Lyase_aromatic PF00221.19 EEQ29919.1 - 0.052 12.2 0.0 1.1 7.8 0.0 2.0 2 0 0 2 2 2 0 Aromatic amino acid lyase HTH_Mga PF08280.11 EEQ29919.1 - 0.22 11.6 0.8 2.1 8.5 0.0 2.7 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Med17 PF10156.9 EEQ29920.1 - 2.6e-95 319.8 0.1 3.5e-95 319.4 0.1 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.20 EEQ29921.1 - 1.5e-192 638.1 0.1 2.4e-106 355.2 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 EEQ29921.1 - 0.052 13.2 0.1 0.23 11.1 0.1 2.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Glyco_hydro_76 PF03663.14 EEQ29922.1 - 6e-158 526.1 6.8 6.9e-158 525.9 6.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EEQ29922.1 - 0.045 12.8 8.0 0.83 8.7 0.1 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 MARVEL PF01284.23 EEQ29923.1 - 0.00033 20.7 2.7 0.28 11.2 0.2 2.1 2 0 0 2 2 2 2 Membrane-associating domain RAC_head PF16717.5 EEQ29924.1 - 2.1e-31 108.8 3.1 2.1e-31 108.8 3.1 3.2 4 1 0 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 EEQ29924.1 - 3.5e-17 62.3 2.2 4e-17 62.1 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain Complex1_LYR PF05347.15 EEQ29925.1 - 3.1e-05 23.9 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) LpoB PF13036.6 EEQ29925.1 - 0.042 13.8 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB RRM_1 PF00076.22 EEQ29926.1 - 1e-09 38.1 0.0 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEQ29926.1 - 0.0023 17.9 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EEQ29926.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Sterol_MT_C PF08498.10 EEQ29927.1 - 1.5e-28 98.9 0.2 2.5e-28 98.2 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EEQ29927.1 - 5.7e-18 65.4 0.0 9.9e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ29927.1 - 1.2e-17 64.4 0.0 2.1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ29927.1 - 1.4e-15 57.4 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EEQ29927.1 - 3.5e-11 42.9 0.0 5.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EEQ29927.1 - 8e-11 42.0 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ29927.1 - 1.4e-10 41.8 0.0 4.3e-10 40.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ29927.1 - 3.5e-09 36.4 0.0 5.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 EEQ29927.1 - 0.00038 20.1 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EEQ29927.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EEQ29927.1 - 0.0024 17.7 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EEQ29927.1 - 0.0062 16.1 0.0 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EEQ29927.1 - 0.008 15.7 0.0 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 EEQ29927.1 - 0.0091 16.0 1.8 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 EEQ29927.1 - 0.043 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 EEQ29927.1 - 0.05 12.9 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain zf-MYND PF01753.18 EEQ29928.1 - 1.9e-08 34.2 12.5 1.9e-08 34.2 12.5 2.7 2 1 0 2 2 2 1 MYND finger Peptidase_S8 PF00082.22 EEQ29929.1 - 5.2e-23 81.7 11.0 9e-23 81.0 11.0 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ29929.1 - 0.038 14.6 0.0 0.12 13.0 0.0 1.8 1 1 1 2 2 2 0 Peptidase inhibitor I9 MFS_1 PF07690.16 EEQ29930.1 - 7.9e-42 143.4 51.1 2.4e-41 141.8 51.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Strabismus PF06638.11 EEQ29930.1 - 0.089 11.4 1.9 0.14 10.8 1.9 1.2 1 0 0 1 1 1 0 Strabismus protein OppC_N PF12911.7 EEQ29930.1 - 2 8.5 6.0 3.8 7.5 1.0 3.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Fungal_trans PF04082.18 EEQ29931.1 - 1.1e-15 57.3 0.0 1.8e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ29931.1 - 2.6e-08 33.8 9.4 4.5e-08 33.1 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.23 EEQ29932.1 - 1e-58 199.2 0.0 1.4e-58 198.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EEQ29932.1 - 9.5e-21 73.4 0.1 4.8e-20 71.1 0.0 2.1 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EEQ29932.1 - 4.6e-08 33.0 0.1 1.1e-06 28.5 0.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EEQ29932.1 - 0.039 14.7 0.3 0.13 13.0 0.2 1.9 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Amidohydro_1 PF01979.20 EEQ29933.1 - 1.7e-70 238.0 0.0 2e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EEQ29933.1 - 1.5e-09 37.9 0.6 5.1e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EEQ29933.1 - 2e-05 24.1 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Toxin_29 PF08116.11 EEQ29933.1 - 0.081 12.9 3.0 0.14 12.2 0.6 2.3 2 0 0 2 2 2 0 PhTx neurotoxin family tRNA_int_end_N2 PF12928.7 EEQ29933.1 - 0.085 13.0 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term DUF3466 PF11949.8 EEQ29933.1 - 0.1 11.2 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Pkinase_fungal PF17667.1 EEQ29934.1 - 1.7e-137 458.5 0.0 2.1e-137 458.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EEQ29934.1 - 0.00014 21.4 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EEQ29934.1 - 0.16 11.8 0.0 0.84 9.5 0.0 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family GDC-P PF02347.16 EEQ29935.1 - 2e-171 570.6 0.0 4.8e-159 529.8 0.0 2.4 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EEQ29935.1 - 2.6e-07 30.2 0.1 6e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EEQ29935.1 - 0.0027 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.21 EEQ29935.1 - 0.07 11.8 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III SepSecS PF05889.13 EEQ29935.1 - 0.15 10.7 0.0 5.3 5.6 0.0 2.1 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Pyridoxal_deC PF00282.19 EEQ29936.1 - 5.2e-97 324.9 0.0 2e-96 323.0 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Abhydrolase_6 PF12697.7 EEQ29937.1 - 7.7e-15 56.1 0.0 9.4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ29937.1 - 9.7e-05 22.1 0.0 0.00039 20.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ29937.1 - 0.00036 19.9 0.0 0.00047 19.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3792 PF12670.7 EEQ29937.1 - 0.029 14.6 0.3 0.052 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) MBOAT_2 PF13813.6 EEQ29938.1 - 6.7e-17 61.5 0.1 1.6e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glyco_hydro_65N PF03636.15 EEQ29939.1 - 7.8e-36 123.8 0.0 1.2e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 EEQ29939.1 - 1.8e-24 86.3 2.0 6.2e-19 68.1 0.8 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 EEQ29939.1 - 0.0003 20.7 0.1 0.00068 19.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain APH PF01636.23 EEQ29940.1 - 3.7e-09 36.9 0.0 5.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ29940.1 - 0.00017 21.2 0.1 0.00031 20.4 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase SMC_Nse1 PF07574.13 EEQ29941.1 - 2.1e-69 233.3 2.4 2.5e-69 233.1 2.4 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EEQ29941.1 - 6.7e-13 48.7 9.2 1.4e-12 47.7 9.2 1.5 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 EEQ29941.1 - 0.00059 20.1 8.2 0.001 19.3 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain PaaX PF07848.12 EEQ29941.1 - 0.031 14.5 0.2 0.071 13.3 0.2 1.6 1 0 0 1 1 1 0 PaaX-like protein Baculo_IE-1 PF05290.11 EEQ29941.1 - 0.035 14.0 5.0 0.057 13.4 2.9 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) AbiEi_4 PF13338.6 EEQ29941.1 - 0.037 14.2 2.6 0.052 13.7 0.3 2.4 2 2 1 3 3 3 0 Transcriptional regulator, AbiEi antitoxin CtsR_C PF17727.1 EEQ29941.1 - 0.076 13.2 0.0 2.1 8.6 0.0 2.7 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain GPP34 PF05719.11 EEQ29941.1 - 0.11 12.5 1.2 7.7 6.5 0.2 2.2 1 1 1 2 2 2 0 Golgi phosphoprotein 3 (GPP34) zf-ANAPC11 PF12861.7 EEQ29941.1 - 0.12 12.4 3.1 0.22 11.6 3.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EEQ29941.1 - 0.18 12.1 5.6 0.4 11.0 5.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 EEQ29941.1 - 0.3 11.3 5.1 0.94 9.7 4.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 EEQ29941.1 - 0.48 10.6 6.1 1.6 8.9 6.1 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EEQ29941.1 - 0.53 10.6 8.8 1.3 9.3 7.7 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain Zf_RING PF16744.5 EEQ29941.1 - 0.62 10.2 8.4 4.3 7.5 8.5 2.2 1 1 1 2 2 2 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 EEQ29941.1 - 1.2 8.8 6.7 2.2 8.0 6.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EEQ29941.1 - 1.8 8.4 7.7 3.6 7.5 7.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EEQ29941.1 - 6.7 6.7 9.6 0.53 10.2 3.9 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.25 EEQ29941.1 - 9.6 6.2 8.3 32 4.5 8.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DAO PF01266.24 EEQ29942.1 - 3.4e-45 155.2 0.2 3.9e-45 154.9 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ29942.1 - 0.0021 18.3 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ29942.1 - 0.015 15.8 0.0 0.08 13.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ29942.1 - 0.02 14.2 0.0 0.88 8.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ29942.1 - 0.027 14.5 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding DJ-1_PfpI PF01965.24 EEQ29943.1 - 2.7e-18 66.3 0.0 4.5e-18 65.6 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EEQ29943.1 - 0.073 12.8 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I AA_permease_2 PF13520.6 EEQ29946.1 - 2.8e-70 237.3 35.1 3.6e-70 236.9 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 EEQ29947.1 - 5.5e-42 143.4 0.0 6.9e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ29947.1 - 2e-26 93.0 0.0 2.3e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ29947.1 - 1.3e-09 38.2 0.0 1.9e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EEQ29947.1 - 0.0006 19.8 0.1 0.0012 18.8 0.0 1.7 2 1 0 2 2 2 1 NAD(P)H-binding TrkA_N PF02254.18 EEQ29947.1 - 0.037 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 EEQ29947.1 - 0.048 13.1 0.0 0.18 11.2 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CBFD_NFYB_HMF PF00808.23 EEQ29948.1 - 1.2e-18 67.1 0.6 1.2e-18 67.1 0.6 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ29948.1 - 4.3e-06 27.1 0.1 1.4e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EEQ29948.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EEQ29948.1 - 0.077 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated YolD PF08863.10 EEQ29948.1 - 0.22 11.6 4.5 0.12 12.4 2.3 1.6 2 0 0 2 2 2 0 YolD-like protein Actin PF00022.19 EEQ29949.1 - 1.3e-09 37.2 0.0 2.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Actin Bystin PF05291.11 EEQ29949.1 - 0.049 12.9 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Bystin Amidase PF01425.21 EEQ29951.1 - 4.2e-108 362.2 0.1 7.3e-108 361.4 0.1 1.3 1 1 0 1 1 1 1 Amidase DUF3347 PF11827.8 EEQ29952.1 - 9.3 6.4 8.3 11 6.1 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) BTRD1 PF17660.1 EEQ29953.1 - 3.8e-95 311.5 19.5 1.5e-20 72.7 0.6 5.0 5 0 0 5 5 5 5 Bacterial tandem repeat domain 1 AvrRpt-cleavage PF05627.11 EEQ29953.1 - 0.0042 16.4 1.3 20 4.7 0.1 4.9 5 0 0 5 5 5 2 Cleavage site for pathogenic type III effector avirulence factor Avr DUF3884 PF13024.6 EEQ29953.1 - 0.013 15.1 0.0 2.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3884) UvrA_inter PF17760.1 EEQ29953.1 - 0.05 13.7 0.2 39 4.4 0.0 4.0 5 0 0 5 5 5 0 UvrA interaction domain DUF4148 PF13663.6 EEQ29953.1 - 0.08 13.1 0.3 0.44 10.8 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) Inhibitor_I34 PF10466.9 EEQ29953.1 - 0.27 11.9 0.5 70 4.1 0.0 3.5 4 0 0 4 4 4 0 Saccharopepsin inhibitor I34 bZIP_2 PF07716.15 EEQ29954.1 - 9.5e-08 32.0 14.9 9.5e-08 32.0 14.9 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 EEQ29954.1 - 2.5e-07 30.7 17.1 5.8e-07 29.5 17.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor FPP PF05911.11 EEQ29954.1 - 0.0012 17.1 6.3 0.0017 16.7 6.3 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil bZIP_Maf PF03131.17 EEQ29954.1 - 0.0053 17.2 12.6 0.011 16.2 12.6 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor SOGA PF11365.8 EEQ29954.1 - 0.025 15.7 1.4 0.025 15.7 1.4 2.6 2 1 1 3 3 3 0 Protein SOGA Striatin PF08232.12 EEQ29954.1 - 0.11 13.1 9.1 0.094 13.3 7.5 1.7 1 1 0 1 1 1 0 Striatin family APG6_N PF17675.1 EEQ29954.1 - 0.16 12.5 12.7 0.28 11.7 12.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Mcm10 PF09332.11 EEQ29954.1 - 0.46 9.8 8.7 0.72 9.2 8.7 1.3 1 0 0 1 1 1 0 Mcm10 replication factor KIAA1430 PF13879.6 EEQ29954.1 - 0.92 10.3 12.1 2.5 8.9 10.5 2.5 2 1 1 3 3 3 0 KIAA1430 homologue CENP-H PF05837.12 EEQ29954.1 - 6.1 7.3 10.5 0.82 10.1 4.6 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Metallophos PF00149.28 EEQ29956.1 - 6.3e-09 36.6 0.2 1.3e-08 35.7 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EEQ29956.1 - 0.00082 19.6 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Transket_pyr PF02779.24 EEQ29957.1 - 7.8e-47 159.2 0.0 1.2e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EEQ29957.1 - 7.4e-34 116.3 0.0 1.8e-33 115.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Glyco_hydro_43 PF04616.14 EEQ29958.1 - 2.2e-50 171.6 5.9 2.1e-49 168.4 5.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 zf-C2H2 PF00096.26 EEQ29959.1 - 0.0041 17.5 1.1 0.0078 16.6 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 EEQ29959.1 - 0.0044 17.3 0.4 0.0081 16.5 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEQ29959.1 - 0.046 14.0 3.3 0.074 13.4 3.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EEQ29959.1 - 0.1 13.5 0.5 0.24 12.3 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1691 PF07950.11 EEQ29960.1 - 8.6e-42 142.2 5.5 2.5e-33 115.0 4.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Phage_holin_3_6 PF07332.11 EEQ29960.1 - 0.14 12.2 5.1 0.083 12.9 0.8 2.4 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III TRM PF02005.16 EEQ29961.1 - 4.6e-110 368.3 0.0 1.4e-94 317.4 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EEQ29961.1 - 0.003 17.3 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF2067 PF09840.9 EEQ29961.1 - 0.01 15.5 0.0 0.029 13.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2067) Methyltransf_31 PF13847.6 EEQ29961.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ29961.1 - 0.046 14.4 0.0 0.13 13.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FAS_I_H PF18314.1 EEQ29962.1 - 5.7e-76 254.7 0.2 3.6e-75 252.1 0.0 2.3 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EEQ29962.1 - 3.3e-75 251.9 0.2 8.3e-75 250.6 0.0 1.8 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EEQ29962.1 - 2.1e-20 73.4 0.0 4.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EEQ29962.1 - 3.2e-18 65.9 0.0 7.3e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EEQ29962.1 - 7e-12 45.4 0.0 1.7e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EEQ29962.1 - 2e-05 24.2 0.0 3.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ29962.1 - 0.00036 20.1 0.0 0.00084 19.0 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ29962.1 - 0.0032 17.4 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1031 PF06275.11 EEQ29962.1 - 0.11 12.7 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) DUF1729 PF08354.10 EEQ29963.1 - 4.1e-157 522.6 0.0 6.2e-157 522.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EEQ29963.1 - 2.7e-95 319.5 0.0 2e-92 310.1 0.0 3.4 3 1 0 3 3 3 2 Acyl transferase domain FAS_meander PF17951.1 EEQ29963.1 - 1.2e-54 184.1 0.0 2.8e-54 182.9 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 EEQ29963.1 - 4.7e-39 132.7 0.0 1.3e-38 131.3 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 EEQ29963.1 - 3.9e-37 128.3 0.3 1.6e-36 126.3 0.0 2.1 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 EEQ29963.1 - 8e-37 126.1 0.0 2.3e-36 124.6 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 EEQ29963.1 - 2e-21 76.5 0.0 5.7e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 EEQ29963.1 - 0.068 12.6 1.0 1.8 7.9 1.0 2.4 1 1 0 1 1 1 0 Nitronate monooxygenase DUF3586 PF12131.8 EEQ29964.1 - 0.013 15.7 0.5 0.02 15.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Gamma-thionin PF00304.20 EEQ29964.1 - 0.034 14.4 2.0 0.051 13.8 2.0 1.3 1 0 0 1 1 1 0 Gamma-thionin family SLR1-BP PF07333.12 EEQ29964.1 - 0.069 13.6 1.1 0.099 13.1 1.1 1.2 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) His_Phos_2 PF00328.22 EEQ29965.1 - 2.7e-107 359.4 0.0 3.5e-107 359.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EEQ29965.1 - 9.2e-38 128.3 0.0 1.9e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EEQ29965.1 - 1.6e-05 24.6 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 EEQ29966.1 - 3.5e-81 272.1 0.6 6.5e-81 271.3 0.6 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EEQ29966.1 - 2e-11 44.2 25.5 0.00028 21.6 0.4 10.0 8 2 1 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ29966.1 - 5e-11 42.8 0.1 0.00085 19.6 0.0 6.3 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain ORC6 PF05460.13 EEQ29966.1 - 0.67 9.2 3.3 1.2 8.3 3.3 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FeoB_associated PF12669.7 EEQ29967.1 - 0.01 16.2 2.0 0.016 15.6 2.0 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4307 PF14155.6 EEQ29967.1 - 0.06 13.2 2.9 0.094 12.6 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) RCR PF12273.8 EEQ29967.1 - 0.25 12.0 5.9 1.8 9.3 5.9 2.1 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red ATG27 PF09451.10 EEQ29967.1 - 0.45 10.3 2.0 0.61 9.9 2.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 PTR2 PF00854.21 EEQ29969.1 - 3.1e-57 194.2 5.7 3.1e-57 194.2 5.7 1.6 1 1 0 1 1 1 1 POT family EBP PF05241.12 EEQ29969.1 - 0.8 9.1 5.8 1.6 8.1 3.9 2.3 2 0 0 2 2 2 0 Emopamil binding protein ATPgrasp_N PF18130.1 EEQ29970.1 - 1e-17 64.4 0.1 2.1e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EEQ29970.1 - 5.3e-12 45.6 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EEQ29970.1 - 1.3e-08 34.6 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EEQ29970.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EEQ29970.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain EccE PF11203.8 EEQ29970.1 - 0.12 12.8 0.1 2.5 8.5 0.1 2.8 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE ATP-grasp PF02222.22 EEQ29970.1 - 0.16 11.5 0.0 0.96 9.0 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain XPG_I_2 PF12813.7 EEQ29971.1 - 1.9e-86 289.6 0.0 3.2e-86 288.8 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing IBR PF01485.21 EEQ29972.1 - 3.8e-10 39.8 41.2 4.9e-07 29.9 8.3 3.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain TFIIF_alpha PF05793.12 EEQ29973.1 - 5.5e-06 25.2 63.8 5.5e-06 25.2 63.8 3.2 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.19 EEQ29974.1 - 9.9e-10 38.5 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EEQ29974.1 - 0.00062 20.0 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Rep-A_N PF04057.12 EEQ29975.1 - 0.00041 20.3 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain AA_permease_2 PF13520.6 EEQ29976.1 - 7.4e-46 156.8 44.7 9.4e-46 156.5 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ29976.1 - 7.7e-22 77.5 35.1 1e-21 77.1 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF383 PF04063.14 EEQ29977.1 - 1.9e-65 220.1 0.0 4.4e-64 215.7 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EEQ29977.1 - 8.2e-21 73.6 1.6 8.2e-21 73.6 1.6 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF384) Antimicrobial_8 PF08103.11 EEQ29977.1 - 0.47 10.7 1.1 1.7 8.9 0.1 2.2 2 0 0 2 2 2 0 Uperin family BESS PF02944.20 EEQ29977.1 - 1.1 9.1 3.8 0.92 9.4 1.2 2.2 2 0 0 2 2 2 0 BESS motif Inositol_P PF00459.25 EEQ29978.1 - 2.4e-52 178.1 0.1 6.3e-52 176.8 0.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.25 EEQ29979.1 - 7e-27 94.4 0.0 1.4e-25 90.2 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ29979.1 - 1.3e-07 31.2 0.1 0.0095 15.2 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ29979.1 - 0.18 10.6 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF676 PF05057.14 EEQ29980.1 - 1.1e-37 129.7 0.0 4.6e-27 95.0 0.0 3.0 2 1 0 2 2 2 2 Putative serine esterase (DUF676) DAGK_cat PF00781.24 EEQ29980.1 - 1.3e-10 41.0 0.0 2.9e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Lipase_3 PF01764.25 EEQ29980.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 EEQ29980.1 - 0.23 10.7 0.1 0.4 10.0 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Fcf1 PF04900.12 EEQ29981.1 - 2.5e-36 124.0 1.3 2.6e-36 124.0 0.3 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EEQ29981.1 - 3.9e-13 49.7 0.4 8.5e-13 48.6 0.1 1.7 2 0 0 2 2 2 1 PIN like domain Ras PF00071.22 EEQ29984.1 - 8.3e-65 217.3 0.1 1e-64 217.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ29984.1 - 3.2e-34 117.7 0.0 4.8e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ29984.1 - 1.7e-13 50.4 0.1 2.1e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ29984.1 - 8.2e-06 25.5 0.1 1.8e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EEQ29984.1 - 1.7e-05 24.3 0.0 2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EEQ29984.1 - 0.00062 19.7 0.1 0.61 10.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EEQ29984.1 - 0.0016 18.5 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ29984.1 - 0.0048 16.4 0.0 0.026 14.1 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EEQ29984.1 - 0.0064 15.9 0.1 0.0079 15.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EEQ29984.1 - 0.15 12.4 0.1 0.9 9.8 0.0 2.0 1 1 0 2 2 2 0 AAA domain NCA2 PF08637.10 EEQ29985.1 - 4.4e-102 341.1 0.1 7.7e-102 340.4 0.1 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 RNA_pol_3_Rpc31 PF11705.8 EEQ29985.1 - 0.02 15.1 2.4 0.034 14.4 2.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Importin_rep_6 PF18829.1 EEQ29985.1 - 0.021 15.0 0.1 0.052 13.7 0.1 1.7 1 0 0 1 1 1 0 Importin repeat 6 FA_hydroxylase PF04116.13 EEQ29986.1 - 5.1e-26 91.6 17.6 5.1e-26 91.6 17.6 1.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily AAA PF00004.29 EEQ29987.1 - 1.9e-50 170.7 0.0 3.2e-34 118.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ29987.1 - 6.2e-14 51.5 0.6 7.2e-08 32.1 0.1 2.9 2 0 0 2 2 2 2 AAA+ lid domain Vps4_C PF09336.10 EEQ29987.1 - 3.4e-06 27.0 0.3 0.079 13.0 0.0 2.8 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 EEQ29987.1 - 0.00011 22.7 0.4 0.018 15.4 0.4 3.3 2 1 0 2 2 2 1 AAA ATPase domain CDC48_N PF02359.18 EEQ29987.1 - 0.00057 20.0 0.1 0.0094 16.1 0.0 2.6 2 1 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain Bac_DnaA PF00308.18 EEQ29987.1 - 0.0012 18.8 0.0 0.016 15.0 0.0 2.6 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_5 PF07728.14 EEQ29987.1 - 0.0015 18.5 0.2 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ29987.1 - 0.0087 16.3 0.0 0.44 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EEQ29987.1 - 0.031 13.8 0.0 4.8 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 EEQ29987.1 - 0.033 14.3 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 EEQ29987.1 - 0.079 12.9 0.0 2.1 8.2 0.1 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea BDHCT_assoc PF16204.5 EEQ29987.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Rrp44_CSD1 PF17216.3 EEQ29987.1 - 0.14 11.8 0.4 0.78 9.5 0.2 2.1 2 0 0 2 2 2 0 Rrp44-like cold shock domain RRM_1 PF00076.22 EEQ29988.1 - 8.4e-14 51.1 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ29988.1 - 0.0055 16.3 0.0 0.0087 15.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ29988.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif PI3_PI4_kinase PF00454.27 EEQ29989.1 - 7.4e-43 147.2 0.0 1.8e-42 145.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 EEQ29989.1 - 5.5e-34 116.1 0.0 2.4e-33 114.1 0.0 2.3 1 0 0 1 1 1 1 UME (NUC010) domain FAT PF02259.23 EEQ29989.1 - 2.8e-32 112.3 0.0 5.6e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 EEQ29989.1 - 0.00033 20.4 0.0 0.00079 19.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.6 EEQ29989.1 - 0.058 14.2 0.2 17 6.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ29989.1 - 0.15 12.6 0.5 12 6.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.23 EEQ29990.1 - 2e-27 95.0 0.1 2.6e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EEQ29990.1 - 1.3e-21 76.8 0.0 1.7e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EEQ29990.1 - 0.0032 17.6 0.4 0.025 14.7 0.4 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 EEQ29990.1 - 0.018 15.1 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 XOO_2897-deam PF14440.6 EEQ29990.1 - 0.036 14.2 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase APOBEC3 PF18771.1 EEQ29990.1 - 0.039 14.1 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 APOBEC4_like PF18774.1 EEQ29990.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase NADH_u_ox_C PF12853.7 EEQ29991.1 - 1.2e-26 92.5 0.1 1.8e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 EEQ29991.1 - 2.6e-08 34.4 0.4 1.4e-07 32.1 0.2 2.2 2 1 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Swi3 PF07962.12 EEQ29992.1 - 2.6e-31 107.4 1.0 5.7e-31 106.4 0.5 1.8 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 DUF2990 PF11693.8 EEQ29992.1 - 0.0035 17.5 0.4 0.18 12.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2990) RCC1 PF00415.18 EEQ29993.1 - 8.6e-61 202.4 13.9 2e-10 41.1 0.3 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EEQ29993.1 - 3.1e-42 141.5 34.3 5.6e-08 32.4 0.7 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DUF966 PF06136.13 EEQ29993.1 - 0.58 9.8 5.4 0.78 9.4 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RibD_C PF01872.17 EEQ29994.1 - 6.6e-29 101.2 0.0 1.1e-28 100.5 0.0 1.4 1 0 0 1 1 1 1 RibD C-terminal domain DUF2890 PF11081.8 EEQ29994.1 - 2 8.5 7.2 3.7 7.6 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nic96 PF04097.14 EEQ29995.1 - 7.1e-210 698.6 0.0 2.2e-208 693.7 0.0 2.1 1 1 0 1 1 1 1 Nup93/Nic96 Pkinase PF00069.25 EEQ29995.1 - 4.6e-19 68.8 0.0 2.4e-18 66.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Nucleoporin_FG PF13634.6 EEQ29995.1 - 0.37 11.7 12.0 0.93 10.4 12.0 1.6 1 0 0 1 1 1 0 Nucleoporin FG repeat region COX16 PF14138.6 EEQ29996.1 - 4.6e-31 107.2 0.1 5.9e-31 106.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Y_phosphatase PF00102.27 EEQ29998.1 - 4.3e-65 219.6 0.3 6.8e-65 218.9 0.3 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EEQ29998.1 - 1.9e-09 38.0 0.0 7.1e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 EEQ29998.1 - 0.0035 17.1 0.2 0.0081 16.0 0.2 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain F-box PF00646.33 EEQ29999.1 - 0.029 14.3 0.1 0.07 13.0 0.1 1.6 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.6 EEQ29999.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain DUF913 PF06025.12 EEQ29999.1 - 2.5 7.0 5.8 29 3.5 5.7 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 EEQ29999.1 - 3 7.2 27.5 3.9 6.8 27.5 1.1 1 0 0 1 1 1 0 SDA1 CPSF100_C PF13299.6 EEQ29999.1 - 3.4 7.8 4.4 11 6.2 4.6 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EEQ29999.1 - 3.9 5.7 21.5 5.1 5.3 21.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EEQ29999.1 - 6.9 6.0 25.5 9.7 5.5 25.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FGGY_C PF02782.16 EEQ30002.1 - 8.9e-51 172.4 0.2 1.5e-50 171.7 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EEQ30002.1 - 1.2e-21 77.4 0.1 1.5e-20 73.8 0.1 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EEQ30002.1 - 0.083 12.4 0.1 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family F-box-like PF12937.7 EEQ30003.1 - 0.0038 17.1 0.2 0.013 15.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like AAA PF00004.29 EEQ30004.1 - 1.6e-43 148.3 0.0 2.6e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ30004.1 - 4.2e-14 52.1 0.0 1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EEQ30004.1 - 9.5e-08 32.3 0.0 1.8e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EEQ30004.1 - 1.5e-07 31.5 0.0 3.7e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEQ30004.1 - 1.8e-06 28.4 0.0 0.00011 22.6 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EEQ30004.1 - 1.4e-05 25.0 1.9 3.7e-05 23.6 1.9 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EEQ30004.1 - 2.6e-05 24.5 0.2 0.0061 16.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EEQ30004.1 - 5.7e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EEQ30004.1 - 0.0008 20.0 0.0 0.019 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EEQ30004.1 - 0.00099 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EEQ30004.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EEQ30004.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EEQ30004.1 - 0.0035 17.2 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EEQ30004.1 - 0.0078 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 EEQ30004.1 - 0.0078 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EEQ30004.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EEQ30004.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EEQ30004.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EEQ30004.1 - 0.022 14.5 0.0 0.097 12.4 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EEQ30004.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EEQ30004.1 - 0.035 13.5 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 EEQ30004.1 - 0.035 14.5 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase HR1 PF02185.16 EEQ30004.1 - 0.036 14.2 0.7 0.092 12.9 0.7 1.7 1 0 0 1 1 1 0 Hr1 repeat AAA_14 PF13173.6 EEQ30004.1 - 0.037 14.1 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EEQ30004.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEQ30004.1 - 0.057 13.0 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EEQ30004.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EEQ30004.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Prot_ATP_OB_N PF17758.1 EEQ30004.1 - 0.14 11.8 0.1 0.5 10.0 0.1 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Na_Ca_ex PF01699.24 EEQ30005.1 - 1.3e-21 77.1 38.3 1.6e-15 57.4 14.8 3.6 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 EEQ30005.1 - 9.7e-15 55.0 10.7 9.7e-15 55.0 10.7 4.9 5 0 0 5 5 5 1 Inner membrane component domain PgaD PF13994.6 EEQ30005.1 - 1.3 9.0 0.0 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 PgaD-like protein Peptidase_S10 PF00450.22 EEQ30006.1 - 2.5e-87 294.0 0.0 3.9e-87 293.4 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase APH PF01636.23 EEQ30007.1 - 2.6e-13 50.5 0.0 5.7e-13 49.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ30007.1 - 0.00032 20.3 0.0 0.00064 19.4 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ30007.1 - 0.0066 15.8 0.0 0.045 13.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 EEQ30007.1 - 0.043 13.2 0.0 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEQ30007.1 - 0.047 13.3 0.1 0.76 9.3 0.0 2.5 2 2 0 2 2 2 0 RIO1 family DNase_NucA_NucB PF14040.6 EEQ30008.1 - 0.0075 16.6 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Pro_isomerase PF00160.21 EEQ30008.1 - 0.038 14.3 0.0 0.068 13.4 0.0 1.6 1 1 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 EEQ30010.1 - 7e-15 55.2 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EEQ30010.1 - 2.7e-10 40.5 0.1 9.9e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Thioesterase PF00975.20 EEQ30010.1 - 0.0098 16.0 1.5 0.049 13.7 0.2 2.4 2 0 0 2 2 2 1 Thioesterase domain PhoH PF02562.16 EEQ30010.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Pkinase_fungal PF17667.1 EEQ30011.1 - 3e-128 428.1 0.0 2.1e-127 425.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EEQ30011.1 - 5.4e-07 29.3 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30011.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 EEQ30011.1 - 0.022 14.7 0.1 0.068 13.1 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 EEQ30012.1 - 1.4e-33 116.3 39.6 6.8e-32 110.8 36.4 3.2 2 1 2 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.13 EEQ30012.1 - 3.2e-07 29.2 18.2 3.2e-07 29.2 18.2 1.7 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ30012.1 - 7.1e-06 25.1 6.6 7.1e-06 25.1 6.6 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter Zn_clus PF00172.18 EEQ30013.1 - 3.7e-07 30.1 7.8 6.2e-07 29.4 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EEQ30014.1 - 7.1e-15 55.0 0.0 1.3e-12 47.6 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ30014.1 - 1.2e-05 25.0 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ30014.1 - 0.00012 22.0 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ30014.1 - 0.0025 17.3 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TerB_C PF15615.6 EEQ30014.1 - 0.15 12.4 0.5 1.8 8.8 0.2 2.1 2 0 0 2 2 2 0 TerB-C domain ADH_N PF08240.12 EEQ30015.1 - 6.1e-10 39.0 0.2 1e-07 31.8 0.0 3.3 2 2 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ30015.1 - 7.8e-09 35.6 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.26 EEQ30016.1 - 3.7e-75 252.8 0.0 1.3e-74 251.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 EEQ30016.1 - 5.6e-70 236.1 0.0 1e-69 235.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EEQ30016.1 - 4.9e-62 210.1 0.0 9.8e-62 209.1 0.0 1.4 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 EEQ30016.1 - 4.8e-49 167.2 0.0 7.5e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EEQ30016.1 - 1.3e-40 139.9 0.0 2.6e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EEQ30016.1 - 2.7e-34 118.7 3.3 9.6e-31 107.1 0.1 3.7 3 1 1 4 4 4 2 KR domain NAD_binding_4 PF07993.12 EEQ30016.1 - 1.3e-33 116.2 0.1 8.3e-32 110.3 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EEQ30016.1 - 3.5e-28 98.0 0.0 8.1e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EEQ30016.1 - 4.6e-21 75.4 0.0 1.2e-20 74.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ30016.1 - 6.6e-17 61.7 0.0 1.7e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EEQ30016.1 - 4.1e-16 59.4 0.0 1.2e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EEQ30016.1 - 9.3e-16 58.3 0.0 3.5e-15 56.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ30016.1 - 1.7e-14 54.2 0.0 6e-14 52.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ30016.1 - 3.2e-14 53.1 0.0 7.3e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EEQ30016.1 - 1.1e-11 44.9 0.1 1.8e-06 28.2 0.0 3.5 3 0 0 3 3 3 2 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EEQ30016.1 - 1.3e-10 41.0 0.0 2.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.21 EEQ30016.1 - 4.2e-10 39.5 0.0 1.1e-09 38.1 0.0 1.7 2 0 0 2 2 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ30016.1 - 1.9e-05 23.8 0.0 0.002 17.2 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.9 EEQ30016.1 - 2.9e-05 23.9 0.0 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 EEQ30016.1 - 0.00023 20.6 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.20 EEQ30016.1 - 0.042 12.9 0.0 0.094 11.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NAD_binding_10 PF13460.6 EEQ30016.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Sec3_C_2 PF15278.6 EEQ30016.1 - 0.14 12.6 0.0 0.48 10.8 0.0 1.9 1 0 0 1 1 1 0 Sec3 exocyst complex subunit APH PF01636.23 EEQ30019.1 - 1.7e-07 31.4 0.1 2.2e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Gln-synt_N PF03951.19 EEQ30020.1 - 0.035 13.8 0.1 0.09 12.5 0.0 1.7 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain Pkinase PF00069.25 EEQ30021.1 - 0.00029 20.3 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30021.1 - 0.19 11.0 0.0 0.66 9.2 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase zf-C2H2 PF00096.26 EEQ30023.1 - 1.6e-08 34.6 6.8 0.00019 21.7 2.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ30023.1 - 3.5e-05 24.3 2.9 0.058 14.3 1.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_12 PF18658.1 EEQ30023.1 - 0.014 15.0 0.3 0.027 14.0 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-CCCH_8 PF18633.1 EEQ30024.1 - 0.046 13.8 0.9 0.11 12.7 0.9 1.7 1 0 0 1 1 1 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 DUF468 PF04318.12 EEQ30028.1 - 0.052 14.3 0.0 0.093 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF468) MFS_1 PF07690.16 EEQ30030.1 - 3.9e-42 144.4 45.3 3.9e-42 144.4 45.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ30030.1 - 0.00041 19.3 24.9 0.0025 16.7 24.9 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Wyosine_form PF08608.12 EEQ30031.1 - 8.1e-22 77.4 0.0 1.7e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EEQ30031.1 - 2.6e-21 76.7 0.0 9.4e-21 74.9 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 EEQ30031.1 - 6.8e-10 39.3 0.1 2e-07 31.3 0.0 2.4 1 1 1 2 2 2 2 Flavodoxin Ald_Xan_dh_C PF01315.22 EEQ30031.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Pro_dh PF01619.18 EEQ30032.1 - 1.2e-65 221.9 1.6 1.6e-65 221.6 1.6 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Aldedh PF00171.22 EEQ30033.1 - 1.2e-103 347.2 0.0 1.5e-103 346.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OCD_Mu_crystall PF02423.15 EEQ30034.1 - 4.1e-11 42.4 0.0 3e-09 36.3 0.0 3.1 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EEQ30034.1 - 1.9e-05 24.7 0.0 0.0026 17.8 0.0 2.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.18 EEQ30035.1 - 2e-05 24.6 10.0 3.1e-05 24.0 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.24 EEQ30036.1 - 1.5e-44 153.1 0.1 4.8e-44 151.4 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EEQ30036.1 - 9.1e-09 35.4 0.0 3.4e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ30036.1 - 6.1e-06 26.7 0.0 7.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ30036.1 - 5.6e-05 22.5 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ30036.1 - 0.0002 21.1 2.4 0.00046 19.9 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EEQ30036.1 - 0.00097 18.3 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EEQ30036.1 - 0.0077 15.5 1.5 0.012 14.8 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EEQ30036.1 - 0.013 14.3 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 EEQ30036.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EEQ30036.1 - 0.041 13.0 0.1 0.058 12.5 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EEQ30036.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EEQ30036.1 - 0.15 11.3 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EEQ30036.1 - 0.15 11.9 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Metallophos_2 PF12850.7 EEQ30038.1 - 4.4e-08 33.5 0.0 4.1e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EEQ30038.1 - 5.3e-07 30.4 0.0 7.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2183 PF09949.9 EEQ30039.1 - 3.3e-32 110.7 1.6 6.4e-32 109.8 0.0 2.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2183) DUF1800 PF08811.11 EEQ30039.1 - 0.005 15.9 2.3 0.0078 15.3 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1800) TFIIA PF03153.13 EEQ30039.1 - 0.032 14.3 14.9 0.02 14.9 9.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CarboxypepD_reg PF13620.6 EEQ30039.1 - 0.081 13.2 0.1 0.85 9.9 0.0 2.5 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain LNS2 PF08235.13 EEQ30039.1 - 0.17 11.3 0.7 0.46 9.9 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF1676 PF07898.13 EEQ30039.1 - 0.27 11.3 0.6 0.47 10.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Spt20 PF12090.8 EEQ30039.1 - 0.62 9.6 13.6 1 8.9 13.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF4199 PF13858.6 EEQ30039.1 - 4.5 7.7 5.9 7.2 7.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2232 PF09991.9 EEQ30039.1 - 8.7 5.4 5.5 13 4.9 5.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Pkinase PF00069.25 EEQ30040.1 - 0.0053 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EEQ30040.1 - 0.04 13.8 0.2 0.094 12.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family U79_P34 PF03064.16 EEQ30040.1 - 5.9 6.2 6.1 10 5.4 6.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PI31_Prot_N PF11566.8 EEQ30041.1 - 5.5e-28 97.8 0.0 7e-25 87.7 0.0 2.1 1 1 1 2 2 2 2 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EEQ30041.1 - 4.4e-19 69.4 11.9 4.4e-19 69.4 11.9 3.4 3 1 1 4 4 4 1 PI31 proteasome regulator Metallophos PF00149.28 EEQ30042.1 - 4.7e-38 131.7 0.4 8.2e-38 131.0 0.4 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EEQ30042.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain adh_short_C2 PF13561.6 EEQ30043.1 - 1.1e-33 116.7 0.1 1.6e-33 116.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ30043.1 - 4e-20 72.1 0.1 5.5e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF3112 PF11309.8 EEQ30044.1 - 3.2e-12 46.4 6.3 9.4e-10 38.3 0.2 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) TPR_1 PF00515.28 EEQ30045.1 - 1.2e-07 31.3 0.2 0.012 15.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ30045.1 - 1.3e-06 28.1 0.6 0.079 13.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ30045.1 - 9.1e-05 22.7 2.3 0.00013 22.2 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ30045.1 - 0.0046 16.9 0.4 2.6 8.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ30045.1 - 0.011 15.4 0.1 0.037 13.7 0.0 1.9 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 EEQ30045.1 - 0.2 12.5 1.1 14 6.9 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EEQ30046.1 - 2.5e-27 95.9 0.0 2.2e-26 92.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30046.1 - 4.3e-12 45.9 0.0 9.7e-11 41.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Scramblase PF03803.15 EEQ30046.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Scramblase HAD_2 PF13419.6 EEQ30047.1 - 4.3e-14 53.0 0.0 6.1e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ30047.1 - 4.2e-07 30.5 0.0 3.6e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ30047.1 - 0.017 15.2 0.0 0.072 13.2 0.0 2.0 2 0 0 2 2 2 0 HAD-hyrolase-like WD40 PF00400.32 EEQ30050.1 - 0.00012 22.8 11.7 9.9 7.2 0.2 6.7 6 2 0 6 6 6 2 WD domain, G-beta repeat Lactonase PF10282.9 EEQ30050.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Nucleoporin_FG PF13634.6 EEQ30051.1 - 2.2e-05 25.2 74.1 0.00081 20.2 39.1 3.4 1 1 1 2 2 2 1 Nucleoporin FG repeat region DUF1664 PF07889.12 EEQ30051.1 - 0.042 13.9 0.7 2.6 8.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ComS PF17584.2 EEQ30052.1 - 0.26 10.8 0.8 3.1 7.4 0.1 2.6 2 0 0 2 2 2 0 Bacillus competence protein S Cpn10 PF00166.21 EEQ30053.1 - 6.9e-21 74.1 0.0 8.7e-21 73.8 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Fip1 PF05182.13 EEQ30054.1 - 7.7e-21 73.3 2.0 1.3e-20 72.6 2.0 1.4 1 0 0 1 1 1 1 Fip1 motif XAP5 PF04921.14 EEQ30055.1 - 7.9e-85 284.7 0.0 1.6e-84 283.7 0.0 1.5 1 1 1 2 2 2 1 XAP5, circadian clock regulator zf-RING_5 PF14634.6 EEQ30056.1 - 1.1e-08 34.9 7.9 2.7e-08 33.6 7.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ30056.1 - 0.00027 20.7 8.4 0.00065 19.5 8.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EEQ30056.1 - 0.0013 19.1 8.9 0.0037 17.5 8.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EEQ30056.1 - 0.0019 18.2 4.4 0.0019 18.2 4.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger CCCAP PF15964.5 EEQ30056.1 - 0.0025 16.2 4.0 0.0039 15.6 4.0 1.3 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family zf-C3HC4 PF00097.25 EEQ30056.1 - 0.0027 17.5 9.5 0.0074 16.1 9.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ30056.1 - 0.0033 17.2 6.5 0.0086 15.9 5.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF1664 PF07889.12 EEQ30056.1 - 0.007 16.4 2.4 0.012 15.6 2.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) DUF4472 PF14739.6 EEQ30056.1 - 0.01 16.6 2.3 0.022 15.5 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Prefoldin PF02996.17 EEQ30056.1 - 0.039 13.9 1.4 0.11 12.4 0.8 1.9 1 1 1 2 2 2 0 Prefoldin subunit AhpC-TSA PF00578.21 EEQ30056.1 - 0.04 13.8 0.4 0.38 10.7 0.1 2.5 2 0 0 2 2 2 0 AhpC/TSA family RmuC PF02646.16 EEQ30056.1 - 0.049 12.8 2.6 0.07 12.2 2.6 1.3 1 0 0 1 1 1 0 RmuC family zf-RING_6 PF14835.6 EEQ30056.1 - 0.074 12.9 4.4 0.15 12.0 4.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-NADH-PPase PF09297.11 EEQ30056.1 - 0.079 12.6 2.1 0.25 11.0 2.1 1.9 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF1732 PF08340.11 EEQ30056.1 - 0.08 12.9 0.8 0.18 11.8 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) DUF4094 PF13334.6 EEQ30056.1 - 0.14 12.6 1.2 0.32 11.5 0.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) zf-C3HC4_4 PF15227.6 EEQ30056.1 - 0.15 12.3 11.6 0.049 13.8 5.5 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Mod_r PF07200.13 EEQ30056.1 - 0.22 11.6 4.2 0.39 10.8 4.2 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Rad50_zn_hook PF04423.14 EEQ30056.1 - 0.25 11.2 2.2 0.95 9.4 0.1 2.6 3 0 0 3 3 3 0 Rad50 zinc hook motif OmpH PF03938.14 EEQ30056.1 - 0.26 11.6 6.1 0.51 10.7 6.2 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) YkyA PF10368.9 EEQ30056.1 - 0.36 10.5 5.1 0.27 10.9 2.6 1.8 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein ZapB PF06005.12 EEQ30056.1 - 0.39 11.2 4.6 0.71 10.4 4.4 1.5 1 1 0 1 1 1 0 Cell division protein ZapB CtIP_N PF10482.9 EEQ30056.1 - 0.45 10.6 5.2 0.18 11.9 1.9 1.9 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain zf-RING_4 PF14570.6 EEQ30056.1 - 0.79 9.6 5.2 2.1 8.2 5.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EEQ30056.1 - 0.87 9.9 7.9 0.58 10.5 5.5 2.0 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 EEQ30056.1 - 2.6 7.8 8.0 0.53 10.0 3.1 2.3 1 1 1 2 2 2 0 P-11 zinc finger IBR PF01485.21 EEQ30056.1 - 6.2 7.1 10.9 3.8 7.8 5.4 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 EEQ30057.1 - 9.9e-10 38.1 12.3 1.6e-09 37.5 12.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEQ30057.1 - 0.13 12.1 13.4 0.24 11.3 13.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF5400 PF17379.2 EEQ30057.1 - 1.6 9.2 5.2 0.3 11.6 0.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5400) Asp PF00026.23 EEQ30058.1 - 2e-17 63.6 0.2 2.7e-17 63.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEQ30058.1 - 0.00089 19.5 0.0 0.0032 17.7 0.0 1.9 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Romo1 PF10247.9 EEQ30058.1 - 0.023 15.1 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 ThiF PF00899.21 EEQ30060.1 - 2.6e-15 56.5 0.0 8.8e-15 54.7 0.0 1.8 1 1 0 1 1 1 1 ThiF family PLU-1 PF08429.11 EEQ30060.1 - 0.05 12.8 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 PLU-1-like protein GAD-like PF08887.11 EEQ30060.1 - 0.094 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 GAD-like domain Rib_5-P_isom_A PF06026.14 EEQ30061.1 - 7.2e-43 146.2 0.0 1.1e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) WD40 PF00400.32 EEQ30062.1 - 1.7e-11 44.5 3.4 0.49 11.3 0.1 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat FHA PF00498.26 EEQ30062.1 - 0.11 12.9 0.0 0.51 10.7 0.0 2.1 2 1 0 2 2 2 0 FHA domain ATP_bind_1 PF03029.17 EEQ30063.1 - 3.2e-78 262.8 0.0 4e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 EEQ30063.1 - 0.00088 19.2 0.0 0.16 11.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 EEQ30063.1 - 0.0014 17.7 0.1 0.0039 16.2 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EEQ30063.1 - 0.0029 17.7 0.0 0.019 15.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.7 EEQ30063.1 - 0.0097 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain KTI12 PF08433.10 EEQ30063.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Fer4_NifH PF00142.18 EEQ30063.1 - 0.028 13.9 0.1 0.058 12.8 0.0 1.5 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 EEQ30063.1 - 0.031 14.6 0.0 0.057 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EEQ30063.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EEQ30063.1 - 0.073 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 EEQ30063.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ30063.1 - 0.078 13.5 0.1 0.24 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EEQ30063.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EEQ30063.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_17 PF13207.6 EEQ30063.1 - 0.11 12.9 0.3 0.11 12.9 0.3 2.1 2 1 0 2 2 2 0 AAA domain Polysacc_deac_2 PF04748.13 EEQ30063.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase AAA_33 PF13671.6 EEQ30063.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNase_P_Rpp14 PF01900.19 EEQ30064.1 - 2.7e-38 130.3 0.0 3.4e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Citrate_synt PF00285.21 EEQ30065.1 - 6.4e-20 71.5 0.0 7.6e-17 61.4 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EEQ30065.1 - 7.8e-19 68.2 0.1 3.1e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EEQ30065.1 - 3e-13 49.8 0.1 5.2e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EEQ30065.1 - 6.3e-05 22.8 0.0 0.0007 19.4 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Citrate_bind PF16114.5 EEQ30066.1 - 6.7e-87 289.6 0.0 9.2e-87 289.1 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EEQ30066.1 - 2.6e-07 30.4 0.0 4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 EEQ30066.1 - 0.066 11.3 0.0 0.088 10.9 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Ank_2 PF12796.7 EEQ30067.1 - 7.8e-07 29.6 0.4 0.017 15.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ30067.1 - 3.6e-05 24.0 2.8 0.0076 16.5 1.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ30067.1 - 0.00041 20.8 0.3 1.9 9.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ30067.1 - 0.65 10.7 7.6 46 5.1 0.2 4.8 5 0 0 5 5 5 0 Ankyrin repeat CFEM PF05730.11 EEQ30068.1 - 4.5e-16 58.7 8.9 6.6e-16 58.2 8.9 1.2 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.11 EEQ30068.1 - 0.088 13.3 6.6 0.13 12.7 6.6 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DNA_pol_delta_4 PF04081.13 EEQ30069.1 - 2.8e-36 124.8 0.8 4e-36 124.3 0.8 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Spore_coat_CotO PF14153.6 EEQ30069.1 - 0.014 15.3 2.2 0.022 14.7 2.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Amidase PF01425.21 EEQ30070.1 - 8.4e-91 305.2 0.0 1.1e-90 304.8 0.0 1.1 1 0 0 1 1 1 1 Amidase APH PF01636.23 EEQ30072.1 - 4.9e-19 69.2 0.0 1.2e-18 68.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EEQ30072.1 - 0.024 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.14 EEQ30072.1 - 0.044 13.0 0.0 4.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.20 EEQ30072.1 - 0.044 13.4 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EEQ30072.1 - 0.049 13.2 0.1 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF1679 PF07914.11 EEQ30072.1 - 0.063 12.1 0.0 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) ORC6 PF05460.13 EEQ30073.1 - 9.1e-45 153.5 7.0 1.5e-44 152.7 7.0 1.3 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Thymosin PF01290.20 EEQ30073.1 - 0.1 12.3 0.2 0.47 10.2 0.1 2.1 2 0 0 2 2 2 0 Thymosin beta-4 family Q_salvage PF10343.9 EEQ30074.1 - 6.8e-132 439.3 0.0 8.2e-132 439.0 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family ThiF PF00899.21 EEQ30075.1 - 9.3e-73 244.6 0.0 1.3e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EEQ30075.1 - 2.5e-21 76.1 0.1 5.7e-21 74.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EEQ30075.1 - 3.7e-07 30.3 5.5 0.00072 19.5 0.1 2.9 3 0 0 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EEQ30075.1 - 5e-05 23.7 0.0 0.00023 21.6 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 EEQ30075.1 - 0.065 13.8 0.0 7.2 7.2 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EEQ30075.1 - 0.067 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase E2_bind PF08825.10 EEQ30075.1 - 0.07 13.3 0.1 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 E2 binding domain adh_short_C2 PF13561.6 EEQ30076.1 - 4.4e-31 108.2 1.4 3.9e-30 105.1 1.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ30076.1 - 2e-30 105.8 2.8 3.7e-29 101.6 2.8 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ30076.1 - 1.3e-07 31.7 2.0 9.1e-07 29.0 2.0 2.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ30076.1 - 5.9e-06 25.9 0.0 1.1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sld7_C PF18596.1 EEQ30076.1 - 0.025 14.7 0.1 0.053 13.7 0.1 1.5 1 0 0 1 1 1 0 Sld7 C-terminal domain Polysacc_synt_2 PF02719.15 EEQ30076.1 - 0.038 13.1 0.0 0.076 12.1 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Skp1_POZ PF03931.15 EEQ30077.1 - 1.5e-09 37.9 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Nif11 PF07862.11 EEQ30077.1 - 0.031 14.6 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 Nif11 domain tRNA_int_end_N2 PF12928.7 EEQ30078.1 - 1.1e-28 99.2 0.0 1.8e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EEQ30078.1 - 0.0048 16.5 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.22 EEQ30079.1 - 2.6e-13 50.6 0.0 7.9e-13 49.0 0.0 1.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 EEQ30080.1 - 3.2e-35 121.7 0.0 4.1e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-ZPR1 PF03367.13 EEQ30081.1 - 4.4e-105 348.4 0.2 5e-55 185.7 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 EEQ30081.1 - 0.088 12.8 1.6 3.7 7.6 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons Rpr2 PF04032.16 EEQ30082.1 - 3e-10 40.3 1.2 3.8e-10 39.9 0.1 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 EEQ30082.1 - 0.0039 17.3 1.2 0.95 9.6 0.1 2.4 2 0 0 2 2 2 2 Zinc ribbon domain zf-ribbon_3 PF13248.6 EEQ30082.1 - 0.13 11.7 1.7 0.54 9.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DBR1 PF05011.13 EEQ30083.1 - 1.3e-43 148.7 0.0 9.8e-43 145.9 0.0 2.4 3 0 0 3 3 3 1 Lariat debranching enzyme, C-terminal domain RTP1_C1 PF10363.9 EEQ30084.1 - 2.6e-31 108.1 0.1 1.3e-30 105.8 0.1 2.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EEQ30084.1 - 4e-10 39.2 0.0 7.5e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Nup88 PF10168.9 EEQ30084.1 - 0.19 9.5 0.1 0.29 8.9 0.1 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF948 PF06103.11 EEQ30084.1 - 0.75 10.1 2.8 1.3 9.4 0.2 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Polysacc_deac_1 PF01522.21 EEQ30086.1 - 6.5e-27 93.9 0.2 1.5e-26 92.7 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EEQ30086.1 - 3.1e-09 37.1 39.8 0.00014 22.2 16.3 2.5 2 0 0 2 2 2 2 Chitin recognition protein RAD51_interact PF15696.5 EEQ30087.1 - 0.044 13.9 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 RAD51 interacting motif FAD_binding_3 PF01494.19 EEQ30089.1 - 6.7e-16 58.5 0.1 3.6e-15 56.1 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EEQ30089.1 - 4.8e-06 26.0 0.4 0.0041 16.4 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ30089.1 - 5e-05 23.8 0.1 0.0026 18.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ30089.1 - 0.00034 20.3 0.6 0.0026 17.4 0.6 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EEQ30089.1 - 0.005 16.0 0.3 0.008 15.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EEQ30089.1 - 0.067 12.4 0.0 4.5 6.4 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase VPS11_C PF12451.8 EEQ30090.1 - 1.6e-17 63.5 0.8 3.9e-17 62.2 0.8 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 EEQ30090.1 - 2.7e-17 63.0 3.5 6.6e-16 58.5 0.9 3.1 4 0 0 4 4 4 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 EEQ30090.1 - 1.3e-07 31.5 8.0 2.4e-07 30.7 8.0 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EEQ30090.1 - 4.5e-06 26.4 6.5 8.7e-06 25.5 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ30090.1 - 0.00047 20.1 6.6 0.00098 19.0 6.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 EEQ30090.1 - 0.00063 19.4 0.1 0.0022 17.6 0.1 1.9 1 0 0 1 1 1 1 TPR repeat zf-RING_2 PF13639.6 EEQ30090.1 - 0.00078 19.7 6.9 0.0015 18.8 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain WD40_like PF17005.5 EEQ30090.1 - 0.0013 18.2 0.2 0.011 15.1 0.0 2.3 3 0 0 3 3 3 1 WD40-like domain TPR_14 PF13428.6 EEQ30090.1 - 0.0073 17.0 0.1 0.38 11.7 0.0 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat zf-rbx1 PF12678.7 EEQ30090.1 - 0.021 15.1 4.7 0.042 14.1 4.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain HPS3_N PF14761.6 EEQ30090.1 - 0.031 13.8 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 zf-C3HC4 PF00097.25 EEQ30090.1 - 0.032 14.1 6.4 0.06 13.2 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4810 PF16068.5 EEQ30090.1 - 0.078 13.5 2.5 1.3 9.6 0.0 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4810) TPR_12 PF13424.6 EEQ30090.1 - 0.079 13.3 0.9 1.6 9.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 EEQ30090.1 - 0.15 12.1 2.7 0.39 10.8 2.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_2 PF07719.17 EEQ30090.1 - 0.53 10.5 2.7 0.69 10.2 0.1 2.7 3 0 0 3 3 1 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 EEQ30090.1 - 0.93 9.6 8.2 2.1 8.5 8.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger TPR_8 PF13181.6 EEQ30090.1 - 1.1 9.6 4.0 1.2 9.5 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat PHD PF00628.29 EEQ30090.1 - 3.4 7.6 5.9 7.3 6.6 5.9 1.6 1 0 0 1 1 1 0 PHD-finger adh_short_C2 PF13561.6 EEQ30091.1 - 7.6e-62 208.9 0.2 8.8e-62 208.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ30091.1 - 4.5e-42 143.7 0.3 5.7e-42 143.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ30091.1 - 1.9e-14 54.0 0.1 2.8e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 EEQ30091.1 - 0.049 13.5 0.1 0.09 12.7 0.1 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Mrr_cat PF04471.12 EEQ30091.1 - 0.14 12.2 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 Restriction endonuclease LRR_4 PF12799.7 EEQ30093.1 - 1.8e-20 72.7 41.6 0.0001 22.6 2.0 9.4 7 1 0 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEQ30093.1 - 2.9e-19 68.6 38.5 2.8e-06 27.0 4.4 7.1 7 0 0 7 7 7 4 Leucine rich repeat LRR_9 PF14580.6 EEQ30093.1 - 3.6e-05 23.3 4.5 0.25 10.8 0.5 3.9 2 2 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 EEQ30093.1 - 0.0083 16.1 35.5 1.4 9.1 0.5 10.0 10 1 1 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.33 EEQ30093.1 - 0.19 12.4 28.6 15 6.7 0.3 10.7 9 3 1 10 10 10 0 Leucine Rich Repeat IPK PF03770.16 EEQ30094.1 - 3.4e-57 193.5 0.0 5.5e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 EEQ30094.1 - 0.075 12.9 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.16 EEQ30096.1 - 1.5e-11 43.9 7.8 2.2e-11 43.3 7.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily INSIG PF07281.12 EEQ30096.1 - 0.027 14.1 0.2 0.17 11.5 0.1 2.2 3 1 0 3 3 3 0 Insulin-induced protein (INSIG) Nodulin-like PF06813.13 EEQ30096.1 - 0.91 9.0 10.6 0.063 12.8 1.2 2.6 3 0 0 3 3 3 0 Nodulin-like ERCC4 PF02732.15 EEQ30097.1 - 3.6e-26 92.2 0.0 7.3e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain RR_TM4-6 PF06459.12 EEQ30097.1 - 0.068 13.0 10.5 0.37 10.6 8.9 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EEQ30097.1 - 1.7 8.8 5.2 21 5.2 5.2 2.3 2 0 0 2 2 2 0 DDHD domain HSA PF07529.13 EEQ30097.1 - 1.9 8.9 19.3 50 4.3 0.1 2.9 1 1 1 2 2 2 0 HSA DUF3043 PF11241.8 EEQ30097.1 - 7.9 6.5 12.3 0.25 11.4 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Atrophin-1 PF03154.15 EEQ30097.1 - 8.9 4.4 13.6 18 3.5 13.6 1.4 1 0 0 1 1 1 0 Atrophin-1 family WD40 PF00400.32 EEQ30098.1 - 1.9e-40 136.1 20.4 1.2e-06 29.1 0.0 8.4 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EEQ30098.1 - 1.6e-11 43.9 1.2 3.4e-11 42.9 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ30098.1 - 1.8e-09 37.2 1.9 2e-09 37.1 0.2 2.1 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 EEQ30098.1 - 2.1e-09 36.6 8.5 0.012 14.2 0.1 5.6 3 2 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EEQ30098.1 - 8.3e-08 32.4 0.3 0.29 11.5 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EEQ30098.1 - 1.1e-05 25.3 0.9 0.00042 20.2 0.0 3.0 3 0 0 3 3 3 1 F-box Ribosomal_S22 PF08136.11 EEQ30098.1 - 0.17 12.3 0.4 0.65 10.4 0.0 2.0 2 0 0 2 2 2 0 30S ribosomal protein subunit S22 family Elongin_A PF06881.11 EEQ30098.1 - 0.29 11.7 3.3 6.3 7.4 3.0 3.0 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Peptidase_M19 PF01244.21 EEQ30099.1 - 1.5e-108 362.7 0.0 1.8e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Glycos_transf_1 PF00534.20 EEQ30100.1 - 8.1e-30 103.6 0.0 1.3e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEQ30100.1 - 1.1e-16 61.3 0.1 1.7e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EEQ30100.1 - 1.7e-13 51.2 0.0 4.3e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EEQ30100.1 - 1.6e-06 28.6 0.1 2.8e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EEQ30100.1 - 3.1e-05 24.3 0.0 6.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 EEQ30100.1 - 0.11 12.5 0.0 9.9 6.1 0.0 2.4 2 0 0 2 2 2 0 ALG11 mannosyltransferase N-terminus Kinesin PF00225.23 EEQ30101.1 - 3.8e-92 308.8 0.1 2.1e-91 306.3 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ30101.1 - 9.5e-20 71.0 0.3 1.6e-15 57.3 0.0 3.7 3 1 0 3 3 3 2 Microtubule binding Sad1_UNC PF07738.13 EEQ30102.1 - 4.5e-14 52.6 0.0 1.2e-06 28.5 0.0 2.2 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal WD40 PF00400.32 EEQ30103.1 - 6.9e-29 99.5 10.4 6.8e-07 29.9 0.5 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 EEQ30103.1 - 1.3e-07 30.7 1.8 0.14 10.8 0.1 5.4 5 1 1 6 6 6 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EEQ30103.1 - 9e-06 25.9 0.0 0.16 12.3 0.0 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1664 PF07889.12 EEQ30103.1 - 0.0011 19.0 3.3 0.0029 17.6 0.6 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EEQ30103.1 - 0.0072 16.5 0.5 0.014 15.6 0.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 EEQ30103.1 - 0.068 12.5 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BBS2_Mid PF14783.6 EEQ30103.1 - 0.078 13.0 0.3 1.5 8.9 0.0 3.2 5 1 1 6 6 6 0 Ciliary BBSome complex subunit 2, middle region CENP-F_leu_zip PF10473.9 EEQ30103.1 - 0.096 12.7 0.8 0.18 11.8 0.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5046 PF16465.5 EEQ30103.1 - 0.11 12.0 0.3 0.64 9.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) RasGAP_C PF03836.15 EEQ30103.1 - 0.14 12.3 0.0 0.77 9.9 0.0 2.0 2 0 0 2 2 2 0 RasGAP C-terminus BCIP PF13862.6 EEQ30105.1 - 1e-74 250.8 0.1 1.2e-74 250.5 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein VID27_N PF17748.1 EEQ30105.1 - 0.11 12.4 0.5 0.18 11.6 0.5 1.3 1 0 0 1 1 1 0 VID27 N-terminal region GMP_synt_C PF00958.22 EEQ30106.1 - 2.9e-42 142.6 0.0 5.7e-42 141.7 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EEQ30106.1 - 1.2e-38 132.9 0.0 1.8e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EEQ30106.1 - 7.3e-10 38.4 0.1 1.1e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EEQ30106.1 - 4.5e-07 29.9 0.1 8e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 EEQ30106.1 - 0.002 17.7 0.0 0.0095 15.5 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EEQ30106.1 - 0.0043 15.9 0.0 0.01 14.7 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase Arginosuc_synth PF00764.19 EEQ30106.1 - 0.019 14.3 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.14 EEQ30106.1 - 0.022 14.4 0.0 0.049 13.2 0.0 1.5 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 EEQ30106.1 - 0.054 13.5 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 EEQ30106.1 - 0.18 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 PP-loop family Condensation PF00668.20 EEQ30108.1 - 0 1332.0 0.0 2.9e-58 197.7 0.0 11.1 10 2 0 10 10 10 10 Condensation domain AMP-binding PF00501.28 EEQ30108.1 - 0 1270.7 0.0 1.3e-81 274.3 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme PP-binding PF00550.25 EEQ30108.1 - 1e-77 256.4 6.4 6.3e-11 42.5 0.2 8.1 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ30108.1 - 8.2e-16 58.8 0.1 0.0011 19.9 0.0 5.8 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EEQ30108.1 - 6.1e-11 41.6 0.1 0.027 13.1 0.0 6.0 6 0 0 6 6 6 5 Transferase family DUF5122 PF17164.4 EEQ30108.1 - 0.26 11.6 0.7 21 5.5 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller ABC_tran PF00005.27 EEQ30109.1 - 1.4e-47 161.7 0.4 2.2e-26 93.0 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ30109.1 - 8.1e-29 101.1 36.4 1.7e-24 86.9 18.1 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EEQ30109.1 - 8.7e-10 38.4 4.1 0.0025 17.3 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEQ30109.1 - 6.1e-09 36.1 4.7 0.012 15.5 0.1 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EEQ30109.1 - 1.6e-06 28.1 0.1 0.00081 19.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EEQ30109.1 - 2.4e-06 27.2 0.8 0.015 15.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EEQ30109.1 - 1.3e-05 25.8 1.6 0.0067 16.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ30109.1 - 2.1e-05 25.0 0.1 0.055 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EEQ30109.1 - 9.4e-05 22.5 0.2 0.19 11.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_19 PF13245.6 EEQ30109.1 - 0.00025 21.4 0.2 0.028 14.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EEQ30109.1 - 0.00039 20.8 0.8 0.087 13.3 0.1 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ30109.1 - 0.00073 19.8 3.2 0.23 11.7 0.2 2.9 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 EEQ30109.1 - 0.0011 18.7 0.1 5.9 6.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 EEQ30109.1 - 0.0016 18.3 0.2 0.2 11.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EEQ30109.1 - 0.0039 17.1 0.1 0.26 11.2 0.1 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EEQ30109.1 - 0.0042 16.8 0.1 0.97 9.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EEQ30109.1 - 0.0048 16.4 0.6 0.43 10.1 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 EEQ30109.1 - 0.0061 15.7 0.2 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.7 EEQ30109.1 - 0.0071 15.3 0.3 2.9 6.7 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain RNA_helicase PF00910.22 EEQ30109.1 - 0.011 16.1 0.4 1.5 9.2 0.1 3.1 2 1 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 EEQ30109.1 - 0.016 14.9 1.0 0.19 11.4 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 EEQ30109.1 - 0.022 14.8 1.7 0.41 10.7 0.2 2.5 2 0 0 2 2 2 0 Dynamin family MeaB PF03308.16 EEQ30109.1 - 0.029 13.4 1.2 2.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 EEQ30109.1 - 0.037 13.2 0.1 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 EEQ30109.1 - 0.039 13.9 3.8 0.1 12.5 0.0 2.9 3 0 0 3 3 2 0 NACHT domain NB-ARC PF00931.22 EEQ30109.1 - 0.041 13.1 5.1 0.28 10.3 0.5 2.6 2 2 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 EEQ30109.1 - 0.066 12.9 0.1 7.2 6.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 EEQ30109.1 - 0.07 12.9 5.3 14 5.4 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_18 PF13238.6 EEQ30109.1 - 0.07 13.7 0.0 7.3 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EEQ30109.1 - 0.079 12.2 0.2 3.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EEQ30109.1 - 0.084 12.5 5.1 0.33 10.5 0.7 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EEQ30109.1 - 0.1 12.2 0.3 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 EEQ30109.1 - 0.1 11.4 0.4 0.38 9.5 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.6 EEQ30109.1 - 0.12 12.4 0.2 0.78 9.8 0.0 2.5 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 EEQ30109.1 - 0.16 11.9 3.4 7.6 6.4 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 EEQ30109.1 - 0.24 11.6 0.3 6.7 6.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EEQ30109.1 - 0.25 10.7 0.8 9.6 5.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 EEQ30109.1 - 0.53 9.0 3.4 2.6 6.7 0.1 3.0 3 1 0 3 3 3 0 Predicted ATPase of the ABC class DUF87 PF01935.17 EEQ30109.1 - 0.99 9.4 5.3 0.54 10.3 0.4 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Rad17 PF03215.15 EEQ30109.1 - 1.3 8.9 5.2 0.78 9.6 0.2 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain Fungal_trans_2 PF11951.8 EEQ30110.1 - 5.5e-43 147.2 0.0 5.3e-29 101.2 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain SelP_N PF04592.14 EEQ30111.1 - 0.44 9.9 9.7 0.65 9.4 9.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MFS_1 PF07690.16 EEQ30112.1 - 3.9e-33 114.8 21.3 3.9e-33 114.8 21.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 EEQ30113.1 - 1.7e-18 66.8 0.0 6.5e-18 64.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ30113.1 - 1.9e-16 60.4 0.0 3.8e-07 29.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ30113.1 - 0.00034 20.6 0.0 0.001 19.0 0.0 1.7 2 0 0 2 2 2 1 KR domain MlaE PF02405.16 EEQ30113.1 - 0.0077 15.9 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 Permease MlaE NAD_binding_10 PF13460.6 EEQ30113.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Amino_oxidase PF01593.24 EEQ30114.1 - 5.4e-68 230.3 0.0 7.9e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EEQ30114.1 - 1.4e-09 38.0 0.1 3.3e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ30114.1 - 0.001 18.4 0.0 0.045 13.0 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEQ30114.1 - 0.0098 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EEQ30114.1 - 0.011 16.2 0.6 0.22 12.1 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HTH_ABP1_N PF18107.1 EEQ30114.1 - 0.016 14.9 0.1 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain DAO PF01266.24 EEQ30114.1 - 0.026 14.1 0.6 0.12 11.9 0.1 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EEQ30114.1 - 0.055 12.8 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EEQ30114.1 - 0.063 13.5 0.6 1.8 8.9 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 EEQ30114.1 - 0.07 13.1 0.2 11 6.0 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EEQ30114.1 - 0.076 13.1 0.2 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 EEQ30114.1 - 0.095 11.9 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EEQ30114.1 - 0.15 11.2 0.0 0.4 9.9 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain RecQ5 PF06959.11 EEQ30121.1 - 0.045 13.7 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) RRM_1 PF00076.22 EEQ30122.1 - 1.8e-08 34.1 0.0 5.2e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EEQ30122.1 - 1.8e-06 28.4 1.1 3e-06 27.7 1.1 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EEQ30122.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif FXMRP1_C_core PF12235.8 EEQ30122.1 - 0.026 15.2 0.1 0.034 14.8 0.1 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Ribosomal_60s PF00428.19 EEQ30122.1 - 1.3 9.7 8.6 1.5 9.4 3.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein HeLo PF14479.6 EEQ30124.1 - 7e-06 26.0 0.1 3.9e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 Prion-inhibition and propagation Glyco_hydro_72 PF03198.14 EEQ30125.1 - 2.2e-119 398.4 0.2 3e-119 398.0 0.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EEQ30125.1 - 7.3e-05 22.3 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MAS20 PF02064.15 EEQ30126.1 - 8.1e-43 145.6 0.1 9.4e-43 145.4 0.1 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Exo84_C PF16528.5 EEQ30127.1 - 6.6e-69 231.8 0.1 6.6e-69 231.8 0.1 2.2 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EEQ30127.1 - 3.8e-16 59.0 2.2 3.8e-16 59.0 2.2 2.2 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 EEQ30127.1 - 0.0013 18.8 1.4 0.0048 17.0 0.1 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2594 PF10769.9 EEQ30127.1 - 0.022 14.8 0.1 0.049 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) Prominin PF05478.11 EEQ30127.1 - 1.5 6.7 4.0 0.51 8.2 0.8 1.7 2 0 0 2 2 2 0 Prominin Baculo_PEP_C PF04513.12 EEQ30127.1 - 5.3 7.1 6.7 0.82 9.7 1.2 2.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EEQ30127.1 - 5.8 6.2 11.0 0.86 8.9 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 EEQ30127.1 - 6.4 7.3 9.4 1.3 9.6 3.0 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 EEQ30127.1 - 9.2 6.9 13.2 1.4 9.6 3.6 2.8 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran PF00005.27 EEQ30128.1 - 2.5e-20 73.4 0.0 1.1e-08 35.7 0.0 3.3 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EEQ30128.1 - 6e-07 29.6 0.1 0.0042 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EEQ30128.1 - 0.00024 21.3 0.0 0.038 14.2 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 EEQ30128.1 - 0.013 14.7 0.1 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Ploopntkinase1 PF18748.1 EEQ30128.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 DUF3584 PF12128.8 EEQ30128.1 - 0.24 8.9 0.0 0.32 8.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CPSase_L_D2 PF02786.17 EEQ30129.1 - 4.9e-115 382.3 0.4 1.7e-83 279.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EEQ30129.1 - 2.5e-49 166.3 0.0 5.1e-49 165.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EEQ30129.1 - 1.1e-46 159.1 0.0 5.4e-46 156.8 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EEQ30129.1 - 4.4e-45 153.3 0.0 9.8e-45 152.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EEQ30129.1 - 2e-39 134.7 0.0 6.4e-39 133.1 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EEQ30129.1 - 2.7e-31 108.8 0.0 7.7e-31 107.3 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EEQ30129.1 - 2e-22 79.2 0.0 1.4e-21 76.5 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EEQ30129.1 - 1.6e-18 67.0 0.5 4.4e-09 36.2 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EEQ30129.1 - 7.3e-17 61.5 0.1 4.1e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EEQ30129.1 - 4.2e-10 39.5 0.0 5.4e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EEQ30129.1 - 6.1e-06 26.4 0.5 0.02 15.0 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EEQ30129.1 - 3.5e-05 23.7 0.1 0.0026 17.5 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 EEQ30129.1 - 0.00046 20.0 0.1 1.5 8.6 0.0 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 EEQ30129.1 - 0.0014 18.4 0.2 1.4 8.7 0.0 4.0 5 0 0 5 5 4 1 DJ-1/PfpI family RimK PF08443.11 EEQ30129.1 - 0.0025 17.4 0.0 1.6 8.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 EEQ30129.1 - 0.045 13.2 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Peptidase_C25_C PF03785.14 EEQ30129.1 - 0.073 12.9 0.4 3.6 7.5 0.3 3.1 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain TrkA_N PF02254.18 EEQ30129.1 - 0.14 12.4 0.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Ion_trans PF00520.31 EEQ30131.1 - 2.1e-09 37.0 27.0 3.3e-09 36.3 27.0 1.2 1 0 0 1 1 1 1 Ion transport protein Synaptobrevin PF00957.21 EEQ30132.1 - 2e-31 107.6 0.0 2.6e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EEQ30132.1 - 9.6e-30 102.5 0.3 1.7e-29 101.7 0.1 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain Ribosomal_L26 PF16906.5 EEQ30133.1 - 1.6e-38 131.0 3.0 1.9e-38 130.7 3.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EEQ30133.1 - 2.1e-08 33.9 2.1 2.1e-08 33.9 2.1 1.7 2 0 0 2 2 2 1 KOW motif DUF1223 PF06764.11 EEQ30133.1 - 0.011 15.8 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) DFRP_C PF16543.5 EEQ30135.1 - 5.1e-25 87.8 12.2 5.1e-25 87.8 12.2 3.4 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 EEQ30135.1 - 1.3e-05 25.8 3.2 1.3e-05 25.8 3.2 3.8 2 2 2 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 EEQ30135.1 - 5.7e-05 22.8 10.2 0.00083 19.1 2.7 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 EEQ30135.1 - 0.00031 20.6 1.3 0.00031 20.6 1.3 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ30135.1 - 0.0012 18.8 6.7 0.0012 18.8 6.7 3.3 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_3 PF15663.5 EEQ30135.1 - 0.0021 18.2 0.7 0.27 11.5 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EEQ30135.1 - 0.23 12.0 14.5 0.31 11.6 4.4 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Snf7 PF03357.21 EEQ30137.1 - 2.2e-20 73.0 14.1 2.5e-20 72.8 11.5 1.9 1 1 1 2 2 2 1 Snf7 DUF826 PF05696.11 EEQ30137.1 - 0.016 15.2 0.1 0.035 14.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF826) MerR-DNA-bind PF09278.11 EEQ30137.1 - 6.6 7.3 14.9 3.2 8.4 1.4 3.9 5 0 0 5 5 5 0 MerR, DNA binding V_ATPase_I PF01496.19 EEQ30137.1 - 8.5 4.1 7.2 4.7 5.0 5.7 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family F-box-like PF12937.7 EEQ30138.1 - 5.5e-09 35.8 0.1 1.2e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ30138.1 - 5.6e-08 32.5 0.2 1.2e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EEQ30138.1 - 0.0072 16.2 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 F-box UIM PF02809.20 EEQ30138.1 - 2.4 8.3 8.2 0.066 13.2 0.5 2.5 3 0 0 3 3 3 0 Ubiquitin interaction motif Mre11_DNA_bind PF04152.14 EEQ30139.1 - 2e-52 177.9 0.1 4.2e-52 176.9 0.1 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EEQ30139.1 - 1.1e-13 52.2 1.5 2.3e-13 51.1 1.5 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEQ30139.1 - 0.00015 22.0 0.0 0.0021 18.3 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CHIP_TPR_N PF18391.1 EEQ30139.1 - 1.4 9.7 5.4 0.29 11.9 1.4 2.0 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain FAM220 PF15487.6 EEQ30139.1 - 4.5 6.8 5.6 9.5 5.8 4.2 2.1 2 0 0 2 2 2 0 FAM220 family AtuA PF07287.11 EEQ30140.1 - 1.4e-125 418.6 0.1 1.7e-125 418.4 0.1 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA GST_C PF00043.25 EEQ30141.1 - 4.8e-15 55.6 0.0 8.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EEQ30141.1 - 6.7e-12 45.6 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ30141.1 - 2.7e-10 40.5 0.0 5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ30141.1 - 8.4e-09 35.3 0.4 1.7e-08 34.4 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EEQ30141.1 - 9.2e-09 35.5 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EEQ30141.1 - 1.2e-06 28.7 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EEQ30141.1 - 0.07 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aldedh PF00171.22 EEQ30142.1 - 4.1e-183 609.1 0.1 4.7e-183 608.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Metallophos PF00149.28 EEQ30143.1 - 5.5e-32 111.9 0.0 1.2e-27 97.7 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EEQ30143.1 - 0.0023 17.6 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EEQ30143.1 - 0.18 12.2 0.3 0.52 10.8 0.0 1.9 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain DIOX_N PF14226.6 EEQ30144.1 - 3.2e-08 34.4 0.0 6.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EEQ30144.1 - 1.5e-05 25.4 0.0 0.00039 20.9 0.0 2.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ctr PF04145.15 EEQ30145.1 - 5.5e-36 124.4 0.0 7.3e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Smg4_UPF3 PF03467.15 EEQ30146.1 - 2.8e-36 125.2 0.0 2.8e-36 125.2 0.0 3.2 4 1 0 4 4 4 1 Smg-4/UPF3 family RRM_1 PF00076.22 EEQ30146.1 - 2.4e-08 33.7 0.3 1.5e-07 31.1 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AbiJ_NTD3 PF18860.1 EEQ30146.1 - 0.019 14.5 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 AbiJ N-terminal domain 3 Tocopherol_cycl PF14249.6 EEQ30147.1 - 0.0053 15.9 0.4 0.0079 15.4 0.4 1.2 1 0 0 1 1 1 1 Tocopherol cyclase zf-C2H2 PF00096.26 EEQ30148.1 - 1.7e-11 43.9 11.8 4.8e-06 26.7 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ30148.1 - 6.1e-08 32.8 9.3 0.00038 21.1 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEQ30148.1 - 5.4e-07 29.7 8.4 2.1e-05 24.7 2.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EEQ30148.1 - 4.4e-05 23.6 4.3 0.014 15.7 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ30148.1 - 0.00082 19.7 5.3 0.4 11.1 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ30148.1 - 0.0014 18.6 5.6 0.52 10.4 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EEQ30148.1 - 0.0072 16.1 0.2 0.0072 16.1 0.2 2.8 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2HE PF16278.5 EEQ30148.1 - 0.056 13.9 8.5 1.2 9.6 1.0 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger BolA PF01722.18 EEQ30148.1 - 0.078 13.3 0.3 1.2 9.5 0.1 2.4 1 1 1 2 2 2 0 BolA-like protein zf-BED PF02892.15 EEQ30148.1 - 0.28 11.2 3.0 0.35 10.9 0.3 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 EEQ30148.1 - 0.33 10.7 3.2 5.7 6.8 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type p450 PF00067.22 EEQ30150.1 - 1.8e-60 205.0 0.0 2.4e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GATA PF00320.27 EEQ30152.1 - 5.3e-15 54.7 1.3 1.1e-14 53.7 1.3 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EEQ30152.1 - 0.086 12.4 0.2 0.24 10.9 0.3 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 EEQ30152.1 - 0.25 11.6 0.2 0.41 10.8 0.2 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) F-box PF00646.33 EEQ30154.1 - 1.7e-06 27.7 0.1 4.9e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EEQ30154.1 - 0.0006 19.7 0.2 0.002 18.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like Cys_rich_CPCC PF14206.6 EEQ30154.1 - 0.042 13.7 0.9 0.042 13.7 0.9 1.8 2 0 0 2 2 2 0 Cysteine-rich CPCC PRANC PF09372.10 EEQ30154.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 PRANC domain Zn_clus PF00172.18 EEQ30156.1 - 8.7e-08 32.2 6.8 1.3e-07 31.7 6.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.18 EEQ30157.1 - 1.2e-10 41.3 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EEQ30157.1 - 0.09 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-AN1 PF01428.16 EEQ30159.1 - 2.3e-13 50.1 4.2 2.3e-13 50.1 4.2 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EEQ30159.1 - 0.01 16.1 4.0 0.01 16.1 4.0 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF1754 PF08555.10 EEQ30160.1 - 1.4e-16 61.1 21.9 1.4e-16 61.1 21.9 1.4 2 0 0 2 2 1 1 Eukaryotic family of unknown function (DUF1754) EccE PF11203.8 EEQ30160.1 - 0.017 15.4 1.1 0.025 14.9 1.1 1.3 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE CDT1 PF08839.11 EEQ30160.1 - 0.34 11.2 3.2 0.42 10.9 3.2 1.1 1 0 0 1 1 1 0 DNA replication factor CDT1 like Rrn6 PF10214.9 EEQ30160.1 - 0.99 7.8 5.8 1.2 7.6 5.8 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 EEQ30160.1 - 1.6 6.9 21.2 1.9 6.7 21.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 EEQ30160.1 - 1.9 8.8 14.1 2.6 8.4 14.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop53 PF07767.11 EEQ30160.1 - 2 7.7 25.4 2.4 7.4 25.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2052 PF09747.9 EEQ30160.1 - 3.4 7.8 19.0 4.2 7.4 19.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RRN3 PF05327.11 EEQ30160.1 - 4.7 5.6 8.5 5.7 5.4 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Trypan_PARP PF05887.11 EEQ30160.1 - 5.4 7.0 8.5 7.3 6.6 8.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SAPS PF04499.15 EEQ30160.1 - 5.9 5.6 8.6 6.4 5.4 8.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HSP70 PF00012.20 EEQ30160.1 - 8.3 4.5 12.6 9.8 4.2 12.6 1.0 1 0 0 1 1 1 0 Hsp70 protein PTPA PF03095.15 EEQ30161.1 - 1.1e-96 323.8 0.3 1e-91 307.5 0.0 2.0 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein DUF202 PF02656.15 EEQ30162.1 - 2.5e-06 27.8 1.5 3.1e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4751 PF15942.5 EEQ30164.1 - 0.19 11.7 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4751) Dicty_REP PF05086.12 EEQ30165.1 - 2.2 6.2 9.6 3.7 5.4 9.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Methyltransf_34 PF11312.8 EEQ30167.1 - 2.5e-100 335.7 0.0 3.1e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Ndr PF03096.14 EEQ30167.1 - 0.074 11.7 0.1 6.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Ndr family CSTF_C PF14304.6 EEQ30167.1 - 0.53 9.9 1.8 17 5.1 0.1 2.3 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Band_7 PF01145.25 EEQ30168.1 - 1.2e-23 84.1 8.4 2.6e-23 82.9 8.4 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EEQ30168.1 - 0.001 18.2 3.9 0.0014 17.7 3.9 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial GatB_Yqey PF02637.18 EEQ30168.1 - 0.027 14.3 0.6 0.046 13.6 0.6 1.4 1 0 0 1 1 1 0 GatB domain UcrQ PF02939.16 EEQ30169.1 - 7.9e-33 112.2 0.4 9.1e-33 112.0 0.4 1.1 1 0 0 1 1 1 1 UcrQ family Ribosomal_L7Ae PF01248.26 EEQ30170.1 - 3.2e-15 55.6 0.1 7.6e-15 54.4 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GGDEF PF00990.21 EEQ30171.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain MMR_HSR1_C PF08438.10 EEQ30172.1 - 2.3e-36 124.7 0.0 5.2e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EEQ30172.1 - 3.4e-16 59.4 0.0 1.7e-15 57.1 0.0 2.0 1 1 2 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ30172.1 - 8.1e-06 25.4 0.0 0.00032 20.3 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEQ30172.1 - 0.0065 16.4 0.9 0.17 11.7 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EEQ30172.1 - 0.0074 15.8 0.4 0.76 9.3 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EEQ30172.1 - 0.045 13.8 2.5 0.22 11.6 0.5 2.6 3 0 0 3 3 3 0 Dynamin family ABC_tran PF00005.27 EEQ30172.1 - 0.052 14.1 0.2 0.79 10.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter KTI12 PF08433.10 EEQ30172.1 - 0.087 12.3 0.1 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Ploopntkinase3 PF18751.1 EEQ30172.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 EEQ30172.1 - 0.12 12.1 0.3 9.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 EEQ30172.1 - 0.13 11.2 0.5 0.57 9.1 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1_Xtn PF16897.5 EEQ30172.1 - 0.13 12.2 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF5615 PF18480.1 EEQ30172.1 - 0.15 11.8 0.1 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) SET PF00856.28 EEQ30174.1 - 0.0083 16.5 0.0 0.028 14.8 0.0 1.9 2 0 0 2 2 2 1 SET domain zf-C4 PF00105.18 EEQ30175.1 - 0.087 13.3 0.1 0.14 12.6 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Fungal_trans PF04082.18 EEQ30176.1 - 6.7e-34 117.1 0.2 1.4e-33 116.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ30176.1 - 1.3e-09 38.0 11.7 2.1e-09 37.3 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 EEQ30176.1 - 0.028 14.0 1.9 0.085 12.4 1.9 1.8 1 0 0 1 1 1 0 Trimerisation motif bZIP_1 PF00170.21 EEQ30176.1 - 0.15 12.2 0.7 0.45 10.6 0.1 2.1 2 0 0 2 2 2 0 bZIP transcription factor Transketolase_N PF00456.21 EEQ30177.1 - 2.3e-152 506.7 0.0 3.1e-152 506.4 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EEQ30177.1 - 4.6e-46 156.7 0.0 7.2e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EEQ30177.1 - 8.7e-12 45.0 0.0 1.7e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EEQ30177.1 - 2.7e-05 23.5 0.0 0.00018 20.8 0.0 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EEQ30177.1 - 0.067 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Beta_elim_lyase PF01212.21 EEQ30177.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Spermine_synth PF01564.17 EEQ30178.1 - 2e-69 232.8 0.0 2.8e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EEQ30178.1 - 1.3e-23 82.6 0.1 2.5e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EEQ30178.1 - 5.5e-05 23.8 0.0 0.00012 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ30178.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ30178.1 - 0.00063 20.4 0.2 0.0029 18.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 EEQ30178.1 - 0.0032 16.7 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain MTS PF05175.14 EEQ30178.1 - 0.057 13.0 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EEQ30178.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain bZIP_1 PF00170.21 EEQ30179.1 - 2.8e-08 33.7 9.8 4.9e-08 33.0 9.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor TMF_TATA_bd PF12325.8 EEQ30179.1 - 0.00034 20.8 2.1 0.00054 20.2 2.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.15 EEQ30179.1 - 0.0014 18.7 6.9 0.0014 18.7 6.9 2.2 1 1 1 2 2 2 1 Basic region leucine zipper Macoilin PF09726.9 EEQ30179.1 - 0.0092 14.6 5.2 0.011 14.3 5.2 1.1 1 0 0 1 1 1 1 Macoilin family SLATT_4 PF18186.1 EEQ30179.1 - 0.02 14.5 0.3 0.031 13.9 0.3 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 GAS PF13851.6 EEQ30179.1 - 0.032 13.6 6.7 0.043 13.2 6.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SHE3 PF17078.5 EEQ30179.1 - 0.048 13.4 4.3 0.071 12.8 4.3 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Troponin PF00992.20 EEQ30179.1 - 0.051 13.9 5.7 0.069 13.4 5.7 1.1 1 0 0 1 1 1 0 Troponin bZIP_Maf PF03131.17 EEQ30179.1 - 0.058 13.9 15.2 0.14 12.7 15.2 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor ASD2 PF08687.11 EEQ30179.1 - 0.061 12.9 6.8 0.072 12.6 6.5 1.3 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 Csm1_N PF18504.1 EEQ30179.1 - 0.096 13.0 5.5 0.68 10.3 1.8 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain GvpL_GvpF PF06386.11 EEQ30179.1 - 0.11 12.5 3.0 0.15 12.0 3.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4254 PF14063.6 EEQ30179.1 - 0.16 11.8 3.1 0.27 11.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) CLZ PF16526.5 EEQ30179.1 - 0.18 12.2 6.5 0.21 12.0 5.6 1.6 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Herpes_UL56 PF04534.12 EEQ30179.1 - 2.6 7.5 7.1 4 6.9 4.0 2.1 1 1 1 2 2 2 0 Herpesvirus UL56 protein DUF2544 PF11245.8 EEQ30182.1 - 0.14 11.6 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2544) G-alpha PF00503.20 EEQ30184.1 - 1.6e-107 359.7 0.0 1.9e-107 359.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EEQ30184.1 - 1.4e-13 50.7 1.2 5.5e-09 35.7 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ30184.1 - 5e-07 29.3 0.1 0.00068 19.1 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region BsuBI_PstI_RE PF06616.11 EEQ30184.1 - 0.0014 17.9 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 BsuBI/PstI restriction endonuclease domain Roc PF08477.13 EEQ30184.1 - 0.0038 17.4 0.1 1.4 9.2 0.0 2.9 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EEQ30184.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 EEQ30184.1 - 0.017 15.2 0.0 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EEQ30184.1 - 0.085 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EEQ30184.1 - 0.097 12.0 0.1 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pet20 PF08692.10 EEQ30185.1 - 0.011 16.4 1.4 0.017 15.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 ATP-synt_C PF00137.21 EEQ30186.1 - 2.4e-36 123.9 34.2 5.1e-22 78.0 15.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Transferase PF02458.15 EEQ30188.1 - 2.1e-27 95.9 0.0 4.9e-16 58.4 0.0 4.0 4 1 0 4 4 4 3 Transferase family GSHPx PF00255.19 EEQ30192.1 - 3e-40 136.1 0.0 3.9e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EEQ30192.1 - 0.012 15.5 0.0 0.036 14.0 0.0 1.9 1 1 0 1 1 1 0 AhpC/TSA family Ndc1_Nup PF09531.10 EEQ30193.1 - 0.66 8.6 2.8 0.7 8.5 2.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hydrolase_6 PF13344.6 EEQ30194.1 - 1e-23 83.3 0.0 2.2e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ30194.1 - 6.9e-12 45.3 0.0 3.4e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EEQ30194.1 - 0.031 14.5 0.0 15 5.8 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF676 PF05057.14 EEQ30195.1 - 9.8e-49 165.8 0.0 1.5e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EEQ30195.1 - 0.00016 21.6 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EEQ30195.1 - 0.00023 21.1 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EEQ30195.1 - 0.00036 21.2 0.0 0.00077 20.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EEQ30195.1 - 0.0095 15.7 0.0 0.031 14.0 0.0 1.8 2 1 0 2 2 2 1 PGAP1-like protein PE-PPE PF08237.11 EEQ30195.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain BTK PF00779.19 EEQ30196.1 - 0.081 12.8 0.6 0.16 11.8 0.6 1.4 1 0 0 1 1 1 0 BTK motif HBD PF18534.1 EEQ30196.1 - 0.1 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Helical bundle domain Ribosomal_L22e PF01776.17 EEQ30197.1 - 1.2e-46 157.6 0.7 1.4e-46 157.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Translin PF01997.16 EEQ30198.1 - 5.9e-53 179.9 0.0 6.8e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Translin family Rx_N PF18052.1 EEQ30198.1 - 0.0065 16.7 1.2 1.1 9.6 0.5 3.3 2 1 0 2 2 2 1 Rx N-terminal domain Syntaxin_2 PF14523.6 EEQ30198.1 - 0.019 15.3 1.0 0.072 13.5 0.2 2.3 3 0 0 3 3 3 0 Syntaxin-like protein Syntaxin-6_N PF09177.11 EEQ30198.1 - 0.15 12.7 0.8 0.61 10.7 0.3 2.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Pcc1 PF09341.10 EEQ30199.1 - 2.3e-33 114.1 2.4 2.9e-33 113.8 2.4 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.6 EEQ30201.1 - 2.7e-39 134.8 0.0 2.8e-37 128.3 0.0 2.8 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EEQ30201.1 - 4.9e-16 58.7 0.0 1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEQ30201.1 - 6.5e-05 22.6 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pyridoxal_deC PF00282.19 EEQ30203.1 - 9.8e-60 202.2 0.0 1.4e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 EEQ30203.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EEQ30203.1 - 0.13 11.2 0.0 0.29 10.0 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-V DUF917 PF06032.12 EEQ30204.1 - 3.2e-121 404.4 0.7 3.9e-120 400.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EEQ30204.1 - 4.5e-29 101.6 4.7 6.5e-24 84.7 1.2 3.3 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EEQ30204.1 - 3.4e-26 92.0 0.1 8.7e-25 87.5 0.0 2.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EEQ30204.1 - 0.003 16.2 1.7 0.08 11.5 0.2 2.8 4 0 0 4 4 4 1 MutL protein BcrAD_BadFG PF01869.20 EEQ30204.1 - 0.0061 16.1 3.3 0.017 14.6 0.1 3.1 3 1 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 EEQ30204.1 - 0.072 12.6 0.1 0.19 11.2 0.1 1.7 1 0 0 1 1 1 0 ROK family FtsA PF14450.6 EEQ30204.1 - 0.079 13.4 7.9 0.2 12.1 0.0 3.9 3 1 0 3 3 3 0 Cell division protein FtsA BRE PF06113.12 EEQ30204.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Homeodomain PF00046.29 EEQ30205.1 - 1.4e-12 47.2 0.0 3.3e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain MFS_1 PF07690.16 EEQ30206.1 - 1.4e-34 119.6 20.9 5.7e-29 101.1 16.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EEQ30206.1 - 9.7e-07 27.4 7.3 1.8e-06 26.6 1.9 2.6 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EEQ30206.1 - 0.00025 19.6 1.5 0.0035 15.8 1.0 2.3 1 1 1 2 2 2 1 Transmembrane secretion effector Fungal_trans_2 PF11951.8 EEQ30207.1 - 6.1e-58 196.5 0.0 7.7e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ30207.1 - 2.8e-07 30.5 12.0 5.3e-07 29.7 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 EEQ30208.1 - 1.4e-40 139.5 0.0 1.9e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.25 EEQ30209.1 - 1.9e-60 204.5 0.0 9.3e-60 202.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30209.1 - 6.4e-29 101.0 0.5 3.1e-20 72.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EEQ30209.1 - 0.00014 21.9 3.0 0.5 10.2 0.0 3.5 2 1 1 3 3 3 3 Phosphotransferase enzyme family Pkinase_C PF00433.24 EEQ30209.1 - 0.00036 21.2 0.8 0.0011 19.6 0.8 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EEQ30209.1 - 0.0004 19.8 0.8 0.0018 17.6 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EEQ30209.1 - 0.02 13.8 0.0 0.036 13.0 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EEQ30209.1 - 0.035 13.5 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1687 PF07955.11 EEQ30210.1 - 5.7e-28 98.0 0.0 7.1e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Abhydrolase_2 PF02230.16 EEQ30211.1 - 3.2e-56 190.5 0.0 3.7e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EEQ30211.1 - 5.5e-07 29.3 0.0 3.2e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EEQ30211.1 - 8.8e-06 25.4 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EEQ30211.1 - 9.7e-05 22.3 0.0 0.011 15.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ30211.1 - 0.00046 19.5 0.4 0.067 12.4 0.0 2.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Esterase PF00756.20 EEQ30211.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.13 EEQ30211.1 - 0.018 14.7 0.0 0.047 13.3 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase_phd PF10503.9 EEQ30211.1 - 0.084 12.4 0.0 0.88 9.0 0.0 2.3 3 0 0 3 3 3 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 EEQ30211.1 - 0.091 13.3 0.0 4.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EEQ30211.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ctr PF04145.15 EEQ30213.1 - 4.9e-29 101.9 0.1 5.8e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FAD_binding_8 PF08022.12 EEQ30214.1 - 4.3e-20 71.8 0.0 8.4e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EEQ30214.1 - 9.1e-19 67.8 11.9 2.2e-18 66.6 11.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EEQ30214.1 - 1.9e-16 60.6 0.0 5.6e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 EEQ30214.1 - 0.056 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain FAD_binding_3 PF01494.19 EEQ30215.1 - 3.4e-67 227.2 0.0 2.8e-65 220.9 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EEQ30215.1 - 3.2e-08 33.8 0.0 1.7e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 EEQ30215.1 - 0.053 12.6 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.6 EEQ30215.1 - 0.11 12.7 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Nup35_RRM PF05172.13 EEQ30216.1 - 0.0069 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1233 PF06806.12 EEQ30216.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative excisionase (DUF1233) EF-1_beta_acid PF10587.9 EEQ30217.1 - 0.063 13.7 3.1 0.063 13.7 3.1 2.1 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Trypan_PARP PF05887.11 EEQ30217.1 - 1.8 8.5 10.7 1.3 9.0 9.4 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1664 PF07889.12 EEQ30218.1 - 0.0075 16.3 1.6 0.16 12.0 1.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EEQ30218.1 - 0.0085 16.4 0.8 0.12 12.7 0.3 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snf7 PF03357.21 EEQ30218.1 - 0.063 12.9 1.0 0.14 11.8 0.9 1.5 1 1 0 1 1 1 0 Snf7 Adenylsucc_synt PF00709.21 EEQ30218.1 - 0.12 11.2 0.1 0.18 10.7 0.0 1.3 1 1 0 1 1 1 0 Adenylosuccinate synthetase Fib_alpha PF08702.10 EEQ30218.1 - 0.19 11.9 1.8 0.32 11.2 1.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Wbp11 PF09429.10 EEQ30220.1 - 3.8e-21 75.3 16.3 3.8e-21 75.3 16.3 1.9 2 0 0 2 2 2 1 WW domain binding protein 11 Nkap_C PF06047.11 EEQ30220.1 - 0.074 13.2 0.2 0.074 13.2 0.2 2.4 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain DUF1176 PF06674.11 EEQ30220.1 - 0.18 11.2 0.1 0.18 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1176) Pkinase PF00069.25 EEQ30221.1 - 6.7e-56 189.6 0.0 6.8e-34 117.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30221.1 - 1.1e-35 123.2 0.0 1.1e-34 119.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ30221.1 - 0.0066 15.3 1.6 0.029 13.1 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase DUF3896 PF13035.6 EEQ30221.1 - 3.5 7.9 5.9 0.66 10.2 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3896) BTB PF00651.31 EEQ30222.1 - 3.5e-27 94.8 0.0 3.9e-14 52.8 0.2 2.8 2 0 0 2 2 2 2 BTB/POZ domain TRP PF06011.12 EEQ30223.1 - 5.9e-75 252.6 23.5 2.4e-74 250.6 23.5 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EEQ30223.1 - 6.4e-36 123.8 0.0 1.3e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 ML-like domain PIG-F PF06699.11 EEQ30223.1 - 0.027 14.6 0.3 0.027 14.6 0.3 2.6 3 0 0 3 3 3 0 GPI biosynthesis protein family Pig-F PhoQ_Sensor PF08918.10 EEQ30223.1 - 0.05 13.4 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 PhoQ Sensor Pkinase PF00069.25 EEQ30224.1 - 4.6e-26 91.7 0.0 2.4e-20 73.0 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30224.1 - 2.5e-05 23.7 0.0 0.014 14.7 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ30224.1 - 0.042 12.6 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Hva1_TUDOR PF11160.8 EEQ30227.1 - 0.11 12.7 0.3 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Hypervirulence associated proteins TUDOR domain zf-C2H2 PF00096.26 EEQ30229.1 - 8.6e-09 35.4 11.2 0.00051 20.3 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ30229.1 - 6.2e-05 23.2 1.0 6.2e-05 23.2 1.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ30229.1 - 0.00053 20.6 9.8 0.12 13.3 1.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EEQ30229.1 - 0.031 14.7 3.1 0.077 13.4 1.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ30229.1 - 0.11 12.5 0.7 0.11 12.5 0.7 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EEQ30229.1 - 0.4 10.8 3.1 10 6.3 0.2 2.6 1 1 1 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 EEQ30229.1 - 4.9 7.3 8.2 1.3 9.1 1.3 2.3 2 0 0 2 2 2 0 BED zinc finger adh_short PF00106.25 EEQ30230.1 - 2.8e-21 75.9 0.0 3.2e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ30230.1 - 1.7e-09 37.6 0.0 1.3e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ30230.1 - 9.5e-09 35.4 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EEQ30230.1 - 0.039 13.1 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAC PF01849.18 EEQ30231.1 - 4.5e-25 87.4 1.5 1.1e-24 86.1 0.7 2.0 2 0 0 2 2 2 1 NAC domain Sigma70_ner PF04546.13 EEQ30231.1 - 0.83 9.5 5.9 0.93 9.3 1.7 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Rpr2 PF04032.16 EEQ30232.1 - 3.8e-22 78.4 1.4 6.6e-22 77.6 1.4 1.4 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.29 EEQ30233.1 - 4.5e-35 121.0 0.0 7.9e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ30233.1 - 2.1e-26 92.4 0.1 7.6e-24 84.2 0.1 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ30233.1 - 1.4e-09 38.2 0.0 2.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EEQ30233.1 - 0.0012 18.2 0.0 0.0053 16.1 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 EEQ30233.1 - 0.023 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Ank_2 PF12796.7 EEQ30234.1 - 1.2e-46 157.1 3.7 1.9e-10 41.2 0.0 7.2 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ30234.1 - 6.8e-37 125.4 5.7 9.1e-08 32.5 0.0 8.5 7 2 1 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ30234.1 - 1e-25 89.5 9.0 1.4e-05 25.3 0.1 8.1 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ30234.1 - 2.1e-22 76.8 10.4 0.041 14.4 0.1 12.3 13 0 0 13 13 13 4 Ankyrin repeat Ank PF00023.30 EEQ30234.1 - 1.8e-20 72.4 16.1 0.049 14.1 0.0 11.3 10 1 1 11 11 11 5 Ankyrin repeat ApbA PF02558.16 EEQ30236.1 - 2.1e-25 89.1 0.0 3.3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EEQ30236.1 - 6.3e-21 74.9 0.1 1.1e-20 74.2 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal RICTOR_M PF14666.6 EEQ30236.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain DASH_Hsk3 PF08227.11 EEQ30237.1 - 1.3e-20 73.4 4.5 1.8e-20 73.0 4.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BBS2_C PF14782.6 EEQ30238.1 - 0.0012 17.7 4.4 0.0014 17.5 4.4 1.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal Lipase_3 PF01764.25 EEQ30239.1 - 6.4e-16 58.5 0.0 1.7e-13 50.6 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EEQ30239.1 - 0.038 14.6 0.8 0.087 13.4 0.8 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ30239.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RGS PF00615.19 EEQ30240.1 - 7.5e-08 32.7 0.0 0.00041 20.6 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain SMC_N PF02463.19 EEQ30241.1 - 4.3e-21 75.4 0.1 6.4e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEQ30241.1 - 1.2e-18 68.4 0.0 1.2e-18 68.4 0.0 4.8 3 2 1 4 4 4 2 AAA domain AAA_15 PF13175.6 EEQ30241.1 - 9.7e-07 28.8 8.3 7.4e-05 22.6 0.0 4.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EEQ30241.1 - 0.00024 21.0 0.2 0.071 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ30241.1 - 0.0029 17.3 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EEQ30241.1 - 0.46 10.1 0.0 0.46 10.1 0.0 4.8 6 0 0 6 6 6 0 AAA domain Baculo_PEP_C PF04513.12 EEQ30241.1 - 0.56 10.2 15.8 3.9 7.5 0.2 5.1 3 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 EEQ30241.1 - 1.7 9.1 61.5 0.68 10.4 2.1 7.7 5 3 2 7 7 7 0 Snapin/Pallidin NPV_P10 PF05531.12 EEQ30241.1 - 2.6 8.6 13.5 7.2 7.2 0.3 5.1 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 EEQ30241.1 - 7.7 4.6 58.6 0.085 11.0 10.4 5.0 4 1 1 5 5 5 0 Septation ring formation regulator, EzrA AdoMet_MTase PF07757.13 EEQ30242.1 - 3.6e-36 123.9 0.3 1.2e-33 115.8 0.3 2.3 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase DUF3237 PF11578.8 EEQ30243.1 - 4.4e-31 107.7 0.0 5.3e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Gln-synt_C PF00120.24 EEQ30244.1 - 1.2e-64 218.6 0.0 9.2e-56 189.3 0.0 2.4 1 1 0 2 2 2 2 Glutamine synthetase, catalytic domain adh_short_C2 PF13561.6 EEQ30245.1 - 4.5e-59 199.8 0.3 5.1e-59 199.7 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ30245.1 - 2.1e-41 141.6 0.2 2.7e-41 141.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ30245.1 - 1.9e-11 44.2 1.1 3.2e-11 43.5 1.1 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EEQ30245.1 - 0.00058 19.8 0.2 0.001 19.0 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EEQ30245.1 - 0.0021 18.7 0.0 0.0044 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 EEQ30245.1 - 0.033 13.3 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RecC_C PF17946.1 EEQ30245.1 - 0.047 13.5 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 RecC C-terminal domain Epimerase PF01370.21 EEQ30245.1 - 0.052 13.0 0.1 0.076 12.5 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 EEQ30245.1 - 0.059 13.5 0.7 0.32 11.1 0.6 2.0 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EEQ30245.1 - 0.13 11.6 1.0 0.2 10.9 0.2 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ChuX_HutX PF06228.13 EEQ30245.1 - 0.16 11.8 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX Myco_arth_vir_N PF09610.10 EEQ30245.1 - 0.2 11.8 1.2 6.1 7.0 0.2 2.5 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Eno-Rase_NADH_b PF12242.8 EEQ30245.1 - 0.38 10.5 2.3 5.1 6.9 0.6 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase gag_pre-integrs PF13976.6 EEQ30247.1 - 4.4e-05 23.3 0.0 7.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain CBP4 PF07960.11 EEQ30248.1 - 8.5e-31 106.5 2.6 9.8e-31 106.3 2.6 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 EEQ30248.1 - 0.0079 16.1 0.1 0.0079 16.1 0.1 2.0 1 1 1 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 FERM_F2 PF18377.1 EEQ30248.1 - 0.07 13.1 0.5 0.07 13.1 0.5 1.6 1 1 1 2 2 2 0 FERM F2 acyl-CoA binding protein-like domain Nbs1_C PF08599.10 EEQ30248.1 - 0.19 11.9 0.0 0.19 11.9 0.0 2.6 1 1 2 3 3 3 0 DNA damage repair protein Nbs1 Tmemb_161AB PF10268.9 EEQ30248.1 - 0.35 9.4 1.2 0.37 9.4 0.0 1.5 1 1 1 2 2 2 0 Predicted transmembrane protein 161AB DUF4407 PF14362.6 EEQ30248.1 - 3.3 7.0 6.3 4.6 6.5 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_76 PF03663.14 EEQ30249.1 - 3.1e-155 517.2 17.5 3.7e-155 516.9 17.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EEQ30249.1 - 0.00017 20.8 13.2 0.0092 15.1 0.4 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Rad21_Rec8_N PF04825.13 EEQ30250.1 - 8.1e-32 109.7 0.0 1.6e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EEQ30250.1 - 0.00066 18.9 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF4006 PF13179.6 EEQ30250.1 - 0.15 12.0 0.2 0.32 11.0 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) NAT PF04768.13 EEQ30251.1 - 8.5e-53 178.5 0.0 2.1e-52 177.2 0.0 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EEQ30251.1 - 1.2e-31 109.7 0.0 3.2e-31 108.3 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EEQ30251.1 - 5.5e-28 98.2 0.3 1.3e-27 97.0 0.0 1.7 2 0 0 2 2 2 1 Amino acid kinase family Synaptobrevin PF00957.21 EEQ30252.1 - 2.3e-32 110.7 1.4 2.6e-32 110.5 1.4 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 EEQ30252.1 - 0.056 14.1 0.1 0.094 13.4 0.1 1.4 1 1 0 1 1 1 0 AT-hook-containing transcription factor EMP24_GP25L PF01105.24 EEQ30252.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1035 PF06281.12 EEQ30252.1 - 0.21 11.6 2.3 0.34 10.9 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) Sel1 PF08238.12 EEQ30254.1 - 7.1e-47 156.8 22.0 3e-09 37.2 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat LigB PF02900.18 EEQ30255.1 - 6.7e-31 107.4 0.0 7.9e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.16 EEQ30256.1 - 2e-10 40.4 0.1 2.5e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.13 EEQ30257.1 - 5.3e-48 161.7 0.2 8.5e-48 161.1 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers FAD_binding_3 PF01494.19 EEQ30258.1 - 1.1e-21 77.5 1.1 3.6e-13 49.5 0.8 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EEQ30258.1 - 3.3e-05 23.3 0.0 0.0063 15.8 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ30258.1 - 0.00012 22.2 0.1 0.0006 20.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ30258.1 - 0.00017 22.1 0.0 0.021 15.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ30258.1 - 0.00081 18.5 0.4 0.006 15.7 0.1 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EEQ30258.1 - 0.0023 17.6 0.0 0.086 12.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EEQ30258.1 - 0.0052 15.9 0.6 0.012 14.7 0.1 1.9 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 EEQ30258.1 - 0.0056 16.0 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EEQ30258.1 - 0.008 15.3 0.0 0.014 14.5 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EEQ30258.1 - 0.01 15.2 0.0 0.05 12.9 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 EEQ30258.1 - 0.08 12.8 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EEQ30258.1 - 0.083 11.6 0.2 0.56 8.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Methyltransf_23 PF13489.6 EEQ30259.1 - 4e-21 75.5 0.0 7.6e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ30259.1 - 7.2e-14 52.3 0.0 2.1e-13 50.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ30259.1 - 3.1e-12 47.0 0.0 6.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ30259.1 - 1.6e-10 41.0 0.0 1.9e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ30259.1 - 9e-10 39.2 0.0 4.4e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EEQ30259.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EEQ30259.1 - 0.00026 20.4 0.0 0.0047 16.3 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EEQ30259.1 - 0.00073 18.9 0.0 0.0028 17.0 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 EEQ30259.1 - 0.0021 17.7 0.0 0.0048 16.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EEQ30259.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EEQ30259.1 - 0.023 14.8 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EEQ30259.1 - 0.032 14.0 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 EEQ30259.1 - 0.094 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Mid2 PF04478.12 EEQ30260.1 - 0.0016 18.3 1.0 0.0023 17.8 1.0 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF575 PF04746.12 EEQ30260.1 - 0.0044 17.2 0.5 0.0076 16.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF575) TrbC PF04956.13 EEQ30260.1 - 0.014 15.6 0.5 0.023 14.9 0.5 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family Amnionless PF14828.6 EEQ30260.1 - 0.1 11.4 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Amnionless SR-25 PF10500.9 EEQ30260.1 - 0.62 9.6 10.3 0.89 9.1 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 EEQ30260.1 - 3 6.0 13.0 4.1 5.6 13.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Malate_synthase PF01274.22 EEQ30261.1 - 1.3e-227 756.3 0.0 1.5e-227 756.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase PsbH PF00737.20 EEQ30262.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein FMO-like PF00743.19 EEQ30263.1 - 6.5e-16 57.8 0.1 2.3e-12 46.1 0.2 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EEQ30263.1 - 2.3e-11 43.7 0.0 1.1e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ30263.1 - 2.3e-08 33.6 0.0 0.00055 19.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ30263.1 - 5e-06 26.3 0.0 0.45 10.0 0.0 3.2 2 1 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 EEQ30263.1 - 0.00018 20.8 0.0 0.019 14.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EEQ30263.1 - 0.0005 19.4 0.1 2.5 7.3 0.0 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEQ30263.1 - 0.034 13.4 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EEQ30263.1 - 0.072 13.7 0.2 0.69 10.5 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ30263.1 - 0.086 12.8 0.1 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EEQ30263.1 - 0.14 10.8 0.1 0.3 9.7 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_3_C PF01915.22 EEQ30264.1 - 8e-45 153.3 0.0 1.5e-44 152.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EEQ30264.1 - 3.5e-36 125.2 0.0 5.4e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EEQ30264.1 - 9.8e-20 70.4 0.0 2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DZR PF12773.7 EEQ30265.1 - 1.8 8.7 8.4 11 6.2 8.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF2039 PF10217.9 EEQ30265.1 - 6 7.3 6.0 22 5.5 6.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Serpin PF00079.20 EEQ30266.1 - 2.7e-56 191.5 0.0 3.1e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) AA_permease_2 PF13520.6 EEQ30267.1 - 5.2e-50 170.5 55.3 6.4e-50 170.2 55.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ30267.1 - 1.7e-19 69.8 40.6 2.5e-19 69.3 40.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4668 PF15701.5 EEQ30267.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4668) Glyco_hydro_18 PF00704.28 EEQ30269.1 - 2.9e-63 214.5 0.1 3.9e-63 214.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EEQ30269.1 - 8.4e-10 39.0 7.5 8.4e-10 39.0 7.5 3.3 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 EEQ30269.1 - 2.6e-05 24.2 0.0 5.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 LysM domain Aspzincin_M35 PF14521.6 EEQ30270.1 - 7.6e-12 46.0 0.0 2e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EEQ30270.1 - 0.056 13.0 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative peptidase family Peptidase_M35 PF02102.15 EEQ30270.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family DUF1512 PF07431.12 EEQ30270.1 - 0.22 10.5 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) F-box PF00646.33 EEQ30271.1 - 0.00031 20.5 1.2 0.00091 19.0 1.2 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EEQ30271.1 - 0.034 14.0 0.1 0.087 12.7 0.1 1.6 1 0 0 1 1 1 0 F-box GST_N_2 PF13409.6 EEQ30272.1 - 1.7e-09 37.8 0.0 4.1e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ30272.1 - 4.2e-08 33.5 0.0 1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ30272.1 - 6.7e-06 26.0 0.1 2.1e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EEQ30272.1 - 0.00038 20.6 0.0 0.00073 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ30272.1 - 0.0078 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.27 EEQ30273.1 - 2.9e-45 154.1 0.1 2.2e-24 86.5 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EEQ30273.1 - 2.1e-15 57.3 0.5 0.00028 20.8 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ30273.1 - 1e-10 41.5 0.6 0.0029 17.1 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EEQ30273.1 - 1.5e-08 34.4 0.1 5e-08 32.7 0.1 2.0 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 EEQ30273.1 - 8.8e-08 32.2 0.0 0.013 15.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EEQ30273.1 - 7.1e-07 29.9 0.8 0.0058 17.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EEQ30273.1 - 8.7e-07 29.0 0.1 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EEQ30273.1 - 1.6e-05 24.5 2.5 0.11 12.3 1.2 2.9 2 1 1 3 3 3 2 P-loop containing region of AAA domain DUF87 PF01935.17 EEQ30273.1 - 7.5e-05 22.9 1.1 0.064 13.4 0.1 3.7 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_28 PF13521.6 EEQ30273.1 - 0.00032 21.0 0.0 0.015 15.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ30273.1 - 0.00035 20.9 0.0 0.7 10.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EEQ30273.1 - 0.00037 20.5 0.5 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 EEQ30273.1 - 0.00063 19.6 0.1 0.89 9.2 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 EEQ30273.1 - 0.0018 18.6 0.1 1.8 9.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.6 EEQ30273.1 - 0.0041 17.3 0.0 3.9 7.8 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 EEQ30273.1 - 0.0044 17.6 0.1 4.8 7.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EEQ30273.1 - 0.012 15.8 0.1 8.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EEQ30273.1 - 0.012 15.3 1.0 1.2 8.8 0.2 2.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EEQ30273.1 - 0.014 15.4 0.0 3.6 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EEQ30273.1 - 0.018 14.8 0.5 2 8.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EEQ30273.1 - 0.02 14.1 0.2 0.83 8.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 EEQ30273.1 - 0.021 14.5 0.2 5 6.7 0.0 2.9 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 EEQ30273.1 - 0.021 13.8 0.4 4 6.3 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ALF PF03752.13 EEQ30273.1 - 0.022 14.7 1.3 0.26 11.3 0.6 2.7 2 0 0 2 2 2 0 Short repeats of unknown function SR-25 PF10500.9 EEQ30273.1 - 0.023 14.3 0.6 0.045 13.4 0.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PduV-EutP PF10662.9 EEQ30273.1 - 0.026 14.3 0.1 0.92 9.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EEQ30273.1 - 0.033 14.6 0.4 3.1 8.2 0.0 3.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Adaptin_N PF01602.20 EEQ30273.1 - 0.041 12.5 0.9 0.22 10.0 0.4 2.0 2 0 0 2 2 2 0 Adaptin N terminal region AAA_13 PF13166.6 EEQ30273.1 - 0.049 12.3 0.0 4.6 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EEQ30273.1 - 0.052 13.7 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EEQ30273.1 - 0.068 13.1 0.0 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MukB PF04310.12 EEQ30273.1 - 0.089 12.6 0.3 2 8.2 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_16 PF13191.6 EEQ30273.1 - 0.092 13.1 0.1 31 4.9 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain DUF3584 PF12128.8 EEQ30273.1 - 0.1 10.1 2.9 1.2 6.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT PF02985.22 EEQ30273.1 - 0.13 12.6 0.9 59 4.3 0.0 4.2 4 0 0 4 4 3 0 HEAT repeat Dynamin_N PF00350.23 EEQ30273.1 - 0.16 12.0 0.2 1.4 9.0 0.0 2.7 3 0 0 3 3 3 0 Dynamin family DUF815 PF05673.13 EEQ30273.1 - 0.19 10.9 0.5 6.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Glyco_hydro_92 PF07971.12 EEQ30274.1 - 3.9e-146 487.6 0.0 5.1e-146 487.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EEQ30274.1 - 3.6e-59 200.6 1.9 5.2e-59 200.0 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DUF1672 PF07901.11 EEQ30274.1 - 0.081 12.2 0.3 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1672) Citrate_synt PF00285.21 EEQ30275.1 - 1.4e-76 258.0 0.0 1e-59 202.4 0.0 2.1 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain ICL PF00463.21 EEQ30276.1 - 8.4e-196 651.5 0.0 9.9e-196 651.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EEQ30276.1 - 4e-11 42.8 0.0 1.5e-10 40.9 0.0 1.8 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase AMP-binding PF00501.28 EEQ30277.1 - 5e-64 216.5 0.0 6.2e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ30277.1 - 3.6e-05 24.7 0.3 9.2e-05 23.3 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.11 EEQ30277.1 - 0.14 11.9 0.4 0.31 10.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) MmgE_PrpD PF03972.14 EEQ30278.1 - 5.7e-147 489.8 0.0 6.7e-147 489.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DNA_methylase PF00145.17 EEQ30279.1 - 3.1e-36 125.4 0.0 1.7e-24 86.8 0.0 3.3 2 1 1 3 3 3 2 C-5 cytosine-specific DNA methylase GATase_6 PF13522.6 EEQ30280.1 - 3.6e-13 49.9 0.0 9.5e-13 48.5 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EEQ30280.1 - 9.5e-12 44.9 0.0 3.2e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EEQ30280.1 - 1.1e-07 31.5 0.0 2.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EEQ30280.1 - 0.00092 18.2 0.0 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HhH-GPD PF00730.25 EEQ30281.1 - 2.3e-07 31.2 0.0 5.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Aldedh PF00171.22 EEQ30282.1 - 4.7e-119 397.9 0.0 5.9e-119 397.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_6 PF12697.7 EEQ30283.1 - 2e-10 41.6 0.6 3.6e-10 40.8 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ30283.1 - 1.4e-09 37.6 0.0 2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ30283.1 - 8.4e-08 32.2 0.2 1.3e-07 31.6 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EEQ30283.1 - 0.00023 21.1 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ30283.1 - 0.00049 19.6 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.14 EEQ30283.1 - 0.096 12.0 0.1 1.9 7.7 0.1 2.1 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_2 PF02230.16 EEQ30283.1 - 0.12 12.2 0.1 3 7.6 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pkinase PF00069.25 EEQ30285.1 - 3.7e-33 115.0 0.0 5.4e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30285.1 - 1.9e-22 79.8 0.0 2.7e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ30285.1 - 0.0071 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ30285.1 - 0.0094 15.3 0.2 0.016 14.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEQ30285.1 - 0.016 14.0 0.1 0.029 13.1 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EEQ30285.1 - 0.028 14.3 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mt_ATP-synt_D PF05873.12 EEQ30288.1 - 1.1e-23 83.8 2.4 1.3e-23 83.6 2.4 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) E3_UbLigase_R4 PF13764.6 EEQ30288.1 - 0.02 13.1 0.6 0.022 12.9 0.6 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 T2SSM_b PF10741.9 EEQ30288.1 - 0.036 13.9 0.5 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF948 PF06103.11 EEQ30288.1 - 0.25 11.6 2.1 1.3 9.3 0.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NAC PF01849.18 EEQ30289.1 - 5.9e-22 77.4 0.0 1.8e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 NAC domain Astro_capsid_p PF12226.8 EEQ30289.1 - 0.17 11.0 4.8 0.22 10.7 1.9 2.0 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Ribosomal_L14e PF01929.17 EEQ30290.1 - 1.5e-30 105.5 2.4 2.2e-30 105.0 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EEQ30290.1 - 5.3e-07 29.4 0.3 9.3e-07 28.6 0.3 1.4 1 0 0 1 1 1 1 KOW motif MFS_1 PF07690.16 EEQ30292.1 - 1.9e-33 115.9 31.8 3.1e-22 79.0 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ30292.1 - 5.5e-12 45.3 11.2 7.7e-12 44.8 2.0 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EEQ30292.1 - 1.8e-06 27.1 11.5 0.00011 21.2 0.6 3.5 2 2 1 3 3 3 2 MFS_1 like family MFS_2 PF13347.6 EEQ30292.1 - 4.5e-05 22.2 13.2 0.0033 16.0 2.1 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein Folate_carrier PF01770.18 EEQ30292.1 - 0.00013 20.9 0.0 0.00022 20.1 0.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier MFS_4 PF06779.14 EEQ30292.1 - 0.00015 21.2 3.5 0.00015 21.2 3.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LacY_symp PF01306.19 EEQ30292.1 - 0.0042 15.9 4.1 0.28 9.9 0.1 2.3 2 1 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.13 EEQ30292.1 - 0.7 8.2 7.4 0.092 11.1 0.6 2.6 2 2 2 4 4 4 0 Transmembrane secretion effector SRP-alpha_N PF04086.13 EEQ30293.1 - 7.6e-67 226.3 0.0 1e-66 225.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EEQ30293.1 - 9.2e-51 172.3 0.0 1.5e-50 171.6 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EEQ30293.1 - 7.8e-10 38.8 0.1 2.3e-09 37.3 0.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EEQ30293.1 - 3.5e-07 29.5 0.0 7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EEQ30293.1 - 0.00085 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EEQ30293.1 - 0.0065 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EEQ30293.1 - 0.011 15.8 0.0 0.044 13.8 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EEQ30293.1 - 0.016 15.6 0.0 0.056 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_31 PF13614.6 EEQ30293.1 - 0.02 14.8 0.3 0.29 11.1 0.0 2.4 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EEQ30293.1 - 0.033 14.3 0.1 0.15 12.1 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase Fer4_NifH PF00142.18 EEQ30293.1 - 0.049 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_17 PF13207.6 EEQ30293.1 - 0.12 12.8 0.1 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain YIF1 PF03878.15 EEQ30295.1 - 3.4e-97 324.7 4.0 4.3e-97 324.3 4.0 1.1 1 0 0 1 1 1 1 YIF1 Catalase PF00199.19 EEQ30296.1 - 5.4e-175 582.1 1.1 6.7e-175 581.8 1.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EEQ30296.1 - 3.7e-16 59.1 0.0 6.9e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EEQ30296.1 - 1.9e-08 34.1 0.1 6.7e-08 32.3 0.0 2.0 3 0 0 3 3 3 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EEQ30296.1 - 9.4e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family F-box PF00646.33 EEQ30297.1 - 0.072 13.0 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 F-box domain RabGAP-TBC PF00566.18 EEQ30298.1 - 1.9e-36 125.7 0.9 3e-36 125.1 0.9 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EEQ30298.1 - 7.2e-08 32.1 0.0 7.4e-07 28.8 0.0 2.5 2 1 0 2 2 2 1 Rab-binding domain (RBD) GAS2 PF02187.17 EEQ30299.1 - 4.6e-06 26.6 0.3 9.9e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.12 EEQ30300.1 - 3.7e-90 302.0 0.0 1.6e-71 240.8 0.0 2.0 1 1 1 2 2 2 2 Hus1-like protein Sec16_C PF12931.7 EEQ30301.1 - 9.9e-113 376.8 0.1 1.4e-112 376.2 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.7 EEQ30301.1 - 2.1e-61 208.1 16.4 2.1e-61 208.1 16.4 4.5 4 0 0 4 4 4 2 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.7 EEQ30301.1 - 9.5e-33 113.3 0.1 2.1e-32 112.2 0.1 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PhoLip_ATPase_C PF16212.5 EEQ30302.1 - 3.8e-46 157.9 7.4 3.8e-46 157.9 7.4 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEQ30302.1 - 1.1e-15 57.1 2.5 2.4e-15 56.0 2.5 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EEQ30302.1 - 2.1e-12 47.8 0.3 1.4e-07 32.0 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ30302.1 - 1.4e-09 37.9 0.2 4.7e-07 29.8 0.0 3.8 3 1 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EEQ30302.1 - 2.4e-05 24.0 0.4 0.053 13.0 0.0 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 EEQ30302.1 - 0.011 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HIGH_NTase1_ass PF16581.5 EEQ30302.1 - 0.033 14.2 0.1 0.08 12.9 0.0 1.6 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Mso1_Sec1_bdg PF14475.6 EEQ30303.1 - 6.7e-14 51.2 0.1 1.3e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 EEQ30304.1 - 1.2e-38 132.3 0.5 2e-38 131.7 0.5 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 EEQ30304.1 - 4.3e-30 104.3 14.3 4.3e-30 104.3 14.3 2.3 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EEQ30304.1 - 9.7e-06 25.2 15.3 1.2e-05 24.8 15.3 1.1 1 0 0 1 1 1 1 BUD22 Ribosomal_L24e PF01246.20 EEQ30304.1 - 0.0081 16.4 0.3 0.022 15.0 0.3 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e PYC_OADA PF02436.18 EEQ30304.1 - 0.033 13.9 1.2 0.061 13.1 0.9 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain Cwf_Cwc_15 PF04889.12 EEQ30304.1 - 0.33 10.6 18.6 0.57 9.9 18.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 EEQ30304.1 - 0.49 8.9 23.4 0.6 8.6 23.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EEQ30304.1 - 5.1 5.2 27.4 6.1 4.9 27.4 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_4 PF13894.6 EEQ30305.1 - 2.6e-07 30.9 35.4 0.066 14.1 1.3 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 EEQ30305.1 - 0.12 12.9 1.3 0.12 12.9 1.3 5.8 6 0 0 6 6 6 0 Zinc finger, C2H2 type MRNIP PF15749.5 EEQ30305.1 - 0.14 12.9 0.6 0.14 12.9 0.6 2.0 2 1 1 3 3 3 0 MRN-interacting protein zf_UBZ PF18439.1 EEQ30305.1 - 0.35 10.5 8.8 13 5.5 0.1 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 EEQ30305.1 - 0.56 10.7 17.3 1.6 9.2 1.0 5.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EEQ30305.1 - 3.8 7.9 22.5 1.5 9.2 6.2 4.2 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) ECH_1 PF00378.20 EEQ30306.1 - 7.3e-26 91.0 0.0 9.2e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EEQ30306.1 - 1.1e-20 74.4 0.0 1.2e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase D123 PF07065.14 EEQ30307.1 - 5.1e-110 367.4 0.1 6e-110 367.2 0.1 1.0 1 0 0 1 1 1 1 D123 DUF1640 PF07798.11 EEQ30308.1 - 2.5e-33 115.6 7.0 2.5e-33 115.6 7.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Vps51 PF08700.11 EEQ30308.1 - 7e-13 48.5 1.4 3.2e-12 46.4 0.0 2.8 3 0 0 3 3 3 1 Vps51/Vps67 HIP1_clath_bdg PF16515.5 EEQ30308.1 - 0.0042 17.7 2.1 0.0042 17.7 2.1 2.8 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 COG2 PF06148.11 EEQ30308.1 - 0.062 13.4 0.8 1 9.5 0.0 3.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Imm49 PF15575.6 EEQ30308.1 - 0.19 11.5 0.8 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 49 ALMT PF11744.8 EEQ30308.1 - 0.25 10.1 4.6 0.13 11.1 1.9 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter HEAT_2 PF13646.6 EEQ30309.1 - 6.7e-08 32.8 0.2 0.32 11.4 0.0 6.1 5 1 0 5 5 5 1 HEAT repeats HEAT PF02985.22 EEQ30309.1 - 0.00058 19.9 10.3 3.2 8.2 0.0 8.4 10 0 0 10 10 10 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EEQ30309.1 - 0.0034 17.9 0.0 0.11 13.2 0.0 3.4 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 EEQ30309.1 - 0.041 13.9 0.3 18 5.5 0.0 5.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EEQ30309.1 - 0.38 10.8 4.1 2.8 8.0 0.0 4.2 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EEQ30309.1 - 0.79 10.3 13.2 47 4.6 0.0 7.1 7 0 0 7 7 7 0 HEAT-like repeat V-ATPase_H_N PF03224.14 EEQ30309.1 - 1.7 7.9 7.0 0.99 8.6 0.1 3.4 3 1 0 3 3 3 0 V-ATPase subunit H Transcrip_reg PF01709.20 EEQ30310.1 - 3.6e-73 245.9 0.1 4.1e-73 245.7 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator CENP-I PF07778.11 EEQ30311.1 - 1.7e-45 155.7 0.1 1.1e-44 153.1 0.1 1.8 1 1 0 1 1 1 1 Mis6 RAMP PF04901.13 EEQ30311.1 - 0.049 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Receptor activity modifying family DUF4360 PF14273.6 EEQ30312.1 - 4.9e-70 235.0 2.1 5.8e-70 234.8 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CLPTM1 PF05602.12 EEQ30313.1 - 1.9e-137 458.8 0.2 2.5e-137 458.4 0.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) MtN3_slv PF03083.16 EEQ30313.1 - 0.58 10.2 5.3 0.092 12.8 0.4 2.1 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange adh_short PF00106.25 EEQ30314.1 - 2.5e-18 66.2 0.0 4.5e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ30314.1 - 1.3e-12 47.8 0.0 1.9e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ASXH PF13919.6 EEQ30315.1 - 1.3e-37 128.9 0.1 2.3e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.6 EEQ30316.1 - 1.4e-26 92.4 0.9 2.3e-26 91.6 0.9 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EEQ30316.1 - 1.9e-13 50.0 1.7 2.7e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Synaptobrevin SLM4 PF16818.5 EEQ30316.1 - 0.0043 17.0 1.5 0.084 12.8 0.1 2.3 1 1 1 2 2 2 1 Protein SLM4 Paf67 PF10255.9 EEQ30316.1 - 0.0056 15.7 0.5 0.049 12.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 SCVP PF17619.2 EEQ30316.1 - 0.065 14.1 0.6 0.81 10.6 0.0 2.2 2 0 0 2 2 2 0 Secreted clade V proteins SIMPL PF04402.14 EEQ30316.1 - 0.32 11.4 3.2 0.62 10.5 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Syntaxin_2 PF14523.6 EEQ30316.1 - 0.33 11.3 5.7 3.7 8.0 0.7 2.2 2 0 0 2 2 2 0 Syntaxin-like protein YgaB PF14182.6 EEQ30316.1 - 0.48 10.9 3.6 0.68 10.4 0.4 2.4 2 1 1 3 3 3 0 YgaB-like protein EMP24_GP25L PF01105.24 EEQ30316.1 - 5.3 6.9 6.8 4 7.4 0.6 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Elong_Iki1 PF10483.9 EEQ30317.1 - 5.1e-101 338.1 0.0 5.8e-101 337.9 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 SNRNP27 PF08648.12 EEQ30318.1 - 2.6e-26 91.4 2.9 5.5e-26 90.4 2.9 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DAO PF01266.24 EEQ30319.1 - 9.8e-69 232.6 0.9 1.1e-68 232.4 0.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ30319.1 - 1e-07 32.0 0.7 4.7e-07 30.0 0.2 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ30319.1 - 3.6e-05 23.1 0.1 0.0035 16.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEQ30319.1 - 0.00097 18.4 0.2 0.0019 17.5 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EEQ30319.1 - 0.0011 18.2 0.2 0.0041 16.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EEQ30319.1 - 0.0012 19.4 0.2 0.012 16.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EEQ30319.1 - 0.0012 17.8 0.1 0.084 11.7 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase MCRA PF06100.11 EEQ30319.1 - 0.0086 14.9 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 MCRA family NAD_binding_9 PF13454.6 EEQ30319.1 - 0.016 15.2 0.2 0.07 13.1 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EEQ30319.1 - 0.063 12.3 0.2 4.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 EEQ30319.1 - 0.14 12.4 0.1 0.56 10.5 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_63 PF03200.16 EEQ30320.1 - 5e-175 583.0 3.1 5e-175 583.0 3.1 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EEQ30320.1 - 1.2e-88 297.0 0.1 4.4e-88 295.2 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EEQ30320.1 - 0.032 13.1 0.4 0.054 12.3 0.4 1.3 1 0 0 1 1 1 0 Trehalase MMtag PF10159.9 EEQ30321.1 - 1.4e-33 115.0 2.3 2.3e-33 114.3 2.3 1.3 1 0 0 1 1 1 1 Multiple myeloma tumor-associated CRT10 PF08728.10 EEQ30322.1 - 2.4e-12 45.9 0.0 2.1e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 CRT10 SDA1 PF05285.12 EEQ30322.1 - 2.1 7.7 16.1 3.5 7.0 16.1 1.2 1 0 0 1 1 1 0 SDA1 DUF3402 PF11882.8 EEQ30323.1 - 8.8e-172 572.4 0.0 1.2e-171 571.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EEQ30323.1 - 6e-84 281.6 0.0 8.2e-84 281.2 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein IBR PF01485.21 EEQ30324.1 - 5.3e-19 68.2 40.2 1e-16 60.9 2.5 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EEQ30324.1 - 6.3e-19 68.4 0.0 1.6e-18 67.1 0.0 1.7 1 1 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 EEQ30324.1 - 0.0065 16.5 9.7 0.0065 16.5 9.7 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EEQ30324.1 - 0.0073 16.6 9.2 0.0073 16.6 9.2 4.1 3 1 1 4 4 4 2 Ring finger domain PAP2 PF01569.21 EEQ30325.1 - 9.8e-17 61.0 4.0 4.4e-16 58.9 4.0 2.0 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EEQ30325.1 - 0.0017 18.5 0.1 0.57 10.3 0.0 2.3 2 0 0 2 2 2 2 Divergent PAP2 family Ldh_2 PF02615.14 EEQ30326.1 - 1.2e-127 425.7 0.1 1.3e-127 425.6 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Pet100 PF09803.9 EEQ30327.1 - 3.4e-19 69.1 0.1 5.3e-19 68.5 0.1 1.3 1 1 0 1 1 1 1 Pet100 CSN7a_helixI PF18392.1 EEQ30327.1 - 0.19 11.7 0.8 0.32 10.9 0.8 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain SPT_ssu-like PF11779.8 EEQ30328.1 - 1e-23 82.7 5.2 1.3e-23 82.3 5.2 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like RF-1 PF00472.20 EEQ30329.1 - 4.4e-18 65.3 13.3 6.9e-13 48.6 12.1 2.3 2 0 0 2 2 2 2 RF-1 domain CAS_CSE1 PF03378.15 EEQ30330.1 - 2e-167 557.2 0.0 4.6e-167 556.0 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EEQ30330.1 - 1.3e-156 521.1 1.8 2e-156 520.5 1.8 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EEQ30330.1 - 1.4e-16 60.1 0.1 6e-16 58.1 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.14 EEQ30330.1 - 0.011 15.0 0.6 0.11 11.8 0.1 2.5 2 0 0 2 2 2 0 V-ATPase subunit H Xpo1 PF08389.12 EEQ30330.1 - 0.044 13.8 1.3 1.1 9.3 0.0 3.8 3 1 0 3 3 3 0 Exportin 1-like protein APH PF01636.23 EEQ30332.1 - 1.7e-05 24.9 0.2 5.9e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ30332.1 - 0.054 13.1 0.3 0.078 12.6 0.3 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3384 PF11864.8 EEQ30333.1 - 1.3e-71 242.0 0.0 2.3e-67 228.0 0.0 3.2 2 2 1 3 3 3 2 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EEQ30333.1 - 9.4e-46 155.7 0.0 1.6e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EEQ30333.1 - 8.5e-38 130.4 2.1 3.5e-33 115.2 0.0 3.2 3 0 0 3 3 3 2 Tuberin RTP1_C1 PF10363.9 EEQ30333.1 - 0.15 12.3 0.0 0.47 10.6 0.0 1.8 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Sororin PF09666.10 EEQ30333.1 - 0.38 11.0 4.1 0.54 10.5 0.0 2.4 2 0 0 2 2 2 0 Sororin protein PUF PF00806.19 EEQ30334.1 - 3.6e-58 190.1 5.8 1.9e-07 30.4 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat EphA2_TM PF14575.6 EEQ30336.1 - 0.045 14.6 0.0 0.062 14.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EEQ30336.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Phosphodiest PF01663.22 EEQ30337.1 - 7.2e-16 58.7 0.5 1.3e-15 57.9 0.5 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EEQ30337.1 - 0.00029 20.3 0.8 0.00029 20.3 0.8 1.5 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 EEQ30337.1 - 0.0004 19.9 0.1 0.00068 19.1 0.1 1.4 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 EEQ30337.1 - 0.092 12.8 0.9 17 5.5 0.1 2.4 2 0 0 2 2 2 0 PglZ domain DUF3402 PF11882.8 EEQ30337.1 - 0.19 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) cwf21 PF08312.12 EEQ30338.1 - 1.3e-14 54.0 21.7 5.2e-14 52.1 21.7 2.1 1 1 0 1 1 1 1 cwf21 domain DUF4407 PF14362.6 EEQ30338.1 - 3 7.1 7.0 4 6.7 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EEQ30338.1 - 5.6 5.9 7.5 7.5 5.5 7.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EEQ30338.1 - 6.6 5.9 4.4 9.6 5.3 4.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein HA2 PF04408.23 EEQ30339.1 - 5.1e-27 94.3 0.0 5.1e-27 94.3 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ30339.1 - 8.6e-13 48.6 0.0 2.9e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EEQ30339.1 - 2.6e-10 40.5 0.0 5.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EEQ30339.1 - 5.8e-09 36.0 0.0 2.5e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EEQ30339.1 - 0.0013 18.8 0.0 1.7 8.6 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEQ30339.1 - 0.0026 18.1 0.0 0.0049 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEQ30339.1 - 0.0067 16.7 0.0 0.025 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEQ30339.1 - 0.018 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EEQ30339.1 - 0.018 15.5 0.0 0.018 15.5 0.0 3.4 4 0 0 4 4 4 0 AAA domain DUF2075 PF09848.9 EEQ30339.1 - 0.066 12.4 0.1 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 EEQ30339.1 - 0.072 12.4 0.0 0.19 11.0 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EEQ30339.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EEQ30339.1 - 0.11 11.6 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PAC3 PF10178.9 EEQ30340.1 - 0.00024 21.2 0.0 0.00047 20.3 0.0 1.5 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 TLP1_add_C PF18313.1 EEQ30341.1 - 2.4e-24 85.1 0.1 7.9e-24 83.4 0.0 1.9 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain Cohesin_load PF10345.9 EEQ30342.1 - 8.7e-166 552.9 12.3 1.1e-165 552.6 12.3 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 EEQ30342.1 - 0.016 15.4 22.1 3 8.2 0.4 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Lactamase_B_4 PF13691.6 EEQ30342.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 tRNase Z endonuclease Histone PF00125.24 EEQ30343.1 - 1e-41 142.4 0.5 1.6e-41 141.8 0.5 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EEQ30343.1 - 7.2e-05 22.9 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EEQ30343.1 - 0.00045 20.6 0.0 0.0007 19.9 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EEQ30343.1 - 0.0064 16.8 0.4 0.013 15.8 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EEQ30343.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DER1 PF04511.15 EEQ30344.1 - 5.6e-46 156.9 5.5 6.5e-46 156.7 5.5 1.0 1 0 0 1 1 1 1 Der1-like family EMP70 PF02990.16 EEQ30345.1 - 8.3e-186 618.7 0.0 1.2e-185 618.1 0.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.23 EEQ30346.1 - 5.2e-18 64.6 0.0 8.2e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EEQ30346.1 - 9.7e-08 31.8 0.1 2.2e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.9 EEQ30346.1 - 4.1e-05 24.1 0.1 9.4e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 EEQ30346.1 - 6.4e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EEQ30346.1 - 8.8e-05 22.6 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 EEQ30346.1 - 0.032 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair STI1 PF17830.1 EEQ30346.1 - 0.037 13.9 1.1 0.037 13.9 1.1 3.0 3 0 0 3 3 3 0 STI1 domain GerD PF17898.1 EEQ30346.1 - 0.43 10.5 5.7 0.88 9.5 4.2 2.1 1 1 1 2 2 2 0 Spore germination GerD central core domain IMUP PF15761.5 EEQ30346.1 - 3.3 8.4 11.2 8.3 7.2 11.2 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein MMS1_N PF10433.9 EEQ30347.1 - 1.7e-160 534.9 0.0 2.5e-160 534.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EEQ30347.1 - 2.1e-104 349.3 0.0 1.1e-102 343.7 0.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 EEQ30347.1 - 0.0084 16.4 0.0 1.2 9.5 0.0 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PRESAN PF09687.10 EEQ30348.1 - 0.038 14.6 0.2 0.086 13.4 0.2 1.5 1 0 0 1 1 1 0 Plasmodium RESA N-terminal CN_hydrolase PF00795.22 EEQ30349.1 - 5.4e-31 107.9 0.0 7.4e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BP28CT PF08146.12 EEQ30350.1 - 2.1e-42 144.7 0.8 6.9e-42 143.0 0.8 2.0 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EEQ30350.1 - 8.1e-24 84.2 2.7 8.1e-24 84.2 2.7 5.5 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 EEQ30350.1 - 0.00031 21.1 4.7 1.2 9.5 0.0 5.7 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 EEQ30350.1 - 0.32 11.4 9.7 0.31 11.4 0.1 5.5 7 0 0 7 7 7 0 HEAT repeat NRDE-2 PF08424.10 EEQ30351.1 - 3e-98 328.9 0.1 1.9e-96 323.0 0.0 3.0 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EEQ30351.1 - 0.0059 17.3 2.4 43 5.3 0.1 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat Suf PF05843.14 EEQ30351.1 - 0.021 14.8 0.1 0.021 14.8 0.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EEQ30351.1 - 1.4 9.5 4.0 0.79 10.2 0.3 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat UDG PF03167.19 EEQ30352.1 - 6.7e-19 68.4 0.0 2.7e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily 7TMR-DISM_7TM PF07695.11 EEQ30353.1 - 0.38 10.6 8.3 0.24 11.2 5.4 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling NAD_binding_6 PF08030.12 EEQ30356.1 - 1.4e-23 83.8 0.0 2.5e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EEQ30356.1 - 1.4e-22 79.8 0.0 3.1e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EEQ30356.1 - 3.1e-20 72.6 10.8 6.4e-20 71.5 10.8 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EEQ30356.1 - 0.032 14.9 0.0 4.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEQ30356.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain SBDS PF01172.18 EEQ30357.1 - 1.1e-26 92.8 0.2 1.3e-26 92.5 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NB-ARC PF00931.22 EEQ30357.1 - 0.05 12.8 0.5 0.11 11.7 0.4 1.6 1 1 0 1 1 1 0 NB-ARC domain RhoGEF PF00621.20 EEQ30358.1 - 9.6e-20 71.6 0.0 3e-19 70.0 0.0 1.9 1 1 0 1 1 1 1 RhoGEF domain Collagen_bind_2 PF12904.7 EEQ30358.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase WSN PF02206.18 EEQ30358.1 - 0.09 12.7 0.0 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function CBP_CCPA PF17040.5 EEQ30358.1 - 4 8.1 8.9 7 7.3 0.5 3.0 3 1 0 3 3 3 0 Cellulose-complementing protein A Nas2_N PF18265.1 EEQ30359.1 - 5.5e-28 96.7 0.0 8.4e-28 96.1 0.0 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EEQ30359.1 - 9.8e-08 31.7 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EEQ30359.1 - 2.4e-07 31.0 0.0 4.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EEQ30359.1 - 4.8e-07 30.2 0.0 7.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 EEQ30359.1 - 7.4e-06 26.2 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 EEQ30360.1 - 8.9e-50 168.5 0.0 1.1e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ30360.1 - 8.2e-30 103.5 0.1 2e-29 102.2 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ30360.1 - 3e-11 43.1 0.0 4.5e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 EEQ30360.1 - 0.00027 21.3 0.1 0.0013 19.1 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EEQ30360.1 - 0.00053 19.4 0.0 0.00068 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ30360.1 - 0.00079 19.5 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EEQ30360.1 - 0.0093 15.2 2.6 1.6 7.8 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit Pox_A32 PF04665.12 EEQ30360.1 - 0.021 14.3 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 EEQ30360.1 - 0.029 14.1 0.2 0.048 13.4 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEQ30360.1 - 0.033 13.7 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EEQ30360.1 - 0.034 14.1 0.0 7.4 6.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 EEQ30360.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EEQ30360.1 - 0.086 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 EEQ30360.1 - 0.097 12.7 0.0 0.26 11.3 0.1 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EEQ30360.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EEQ30360.1 - 0.15 11.4 0.4 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Septin SNF2_N PF00176.23 EEQ30361.1 - 8.7e-61 205.6 0.4 8.7e-61 205.6 0.4 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ30361.1 - 1.6e-14 54.2 0.0 3.6e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EEQ30361.1 - 1.2e-08 34.7 2.8 2.3e-08 33.8 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ30361.1 - 3.3e-08 33.2 1.8 3.3e-08 33.2 1.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EEQ30361.1 - 3.7e-06 27.0 0.0 9.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EEQ30361.1 - 2e-05 24.3 3.5 5.3e-05 23.0 3.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ30361.1 - 4.1e-05 23.8 4.2 0.00011 22.5 4.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EEQ30361.1 - 7.9e-05 22.6 2.3 0.00019 21.4 2.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ30361.1 - 0.00087 19.2 3.5 0.0021 18.0 3.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EEQ30361.1 - 0.0011 18.7 2.5 0.0032 17.2 2.5 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EEQ30361.1 - 0.0025 17.6 6.2 0.02 14.8 6.5 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 DZR PF12773.7 EEQ30361.1 - 0.032 14.2 2.4 0.1 12.7 2.4 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 EEQ30361.1 - 0.037 14.2 5.4 0.086 13.0 5.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1644 PF07800.12 EEQ30361.1 - 4.6 7.3 5.9 31 4.6 2.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) Spt5_N PF11942.8 EEQ30361.1 - 9.8 7.2 12.0 3.4 8.7 4.0 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal F-box-like PF12937.7 EEQ30362.1 - 0.0057 16.5 0.0 5.5 7.0 0.0 2.5 2 0 0 2 2 2 2 F-box-like SCP2 PF02036.17 EEQ30363.1 - 7.3e-24 84.2 0.1 8.5e-24 84.0 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EEQ30363.1 - 3.3e-05 24.2 0.0 4.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Ran_BP1 PF00638.18 EEQ30364.1 - 9.8e-13 48.4 0.0 1.8e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 EEQ30364.1 - 0.014 16.3 186.1 0.017 15.9 19.8 10.4 3 2 7 10 10 10 0 Nucleoporin FG repeat region Ribosomal_L31e PF01198.19 EEQ30365.1 - 4.2e-41 139.1 0.6 5.3e-41 138.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.18 EEQ30365.1 - 0.082 12.4 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel CN_hydrolase PF00795.22 EEQ30366.1 - 1.2e-60 205.0 0.0 1.4e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PA PF02225.22 EEQ30366.1 - 0.15 12.1 0.0 0.66 10.0 0.0 2.0 2 0 0 2 2 2 0 PA domain Fungal_trans PF04082.18 EEQ30367.1 - 1.5e-08 34.0 2.3 2.4e-08 33.4 2.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ30367.1 - 3.6e-06 27.0 8.0 6.7e-06 26.1 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF885 PF05960.11 EEQ30367.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) FAD_binding_3 PF01494.19 EEQ30368.1 - 4.7e-25 88.6 0.0 1.6e-18 67.1 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 EEQ30368.1 - 8.6e-08 31.5 1.6 2.4e-05 23.4 0.1 2.4 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EEQ30368.1 - 3.5e-06 26.5 0.1 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ30368.1 - 0.00033 19.8 0.0 0.0006 19.0 0.0 1.3 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EEQ30368.1 - 0.002 18.3 0.5 0.0059 16.8 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ30368.1 - 0.0088 16.6 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ30368.1 - 0.051 12.8 0.2 0.1 11.8 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thioesterase PF00975.20 EEQ30369.1 - 5e-21 75.9 0.1 9.4e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EEQ30369.1 - 8.2e-07 28.9 0.0 1.3e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ30369.1 - 1.6e-05 25.7 0.0 1.6e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EEQ30369.1 - 0.027 14.2 0.0 0.39 10.5 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ30369.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EEQ30369.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 EEQ30369.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Asp PF00026.23 EEQ30370.1 - 9.3e-12 45.0 0.1 5.5e-07 29.3 0.0 2.2 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Crl PF07417.12 EEQ30370.1 - 0.039 14.0 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma factor-binding transcriptional regulator Crl p450 PF00067.22 EEQ30371.1 - 9.7e-50 169.6 0.0 1.6e-49 168.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF2953 PF11167.8 EEQ30371.1 - 0.14 12.3 0.0 0.57 10.3 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) AMP-binding PF00501.28 EEQ30372.1 - 1.8e-79 267.4 0.0 2.6e-79 266.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EEQ30372.1 - 2.2e-76 257.4 0.0 3.5e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.26 EEQ30372.1 - 1.6e-73 247.4 0.0 3.5e-73 246.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EEQ30372.1 - 8.7e-61 205.7 0.0 1.3e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EEQ30372.1 - 8.2e-60 201.8 0.4 5.6e-59 199.1 0.0 2.6 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 EEQ30372.1 - 8.4e-57 193.1 0.0 1.4e-56 192.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ30372.1 - 1.5e-39 134.7 0.1 8.3e-39 132.3 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EEQ30372.1 - 6.1e-36 123.9 0.0 1.3e-35 122.8 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein KAsynt_C_assoc PF16197.5 EEQ30372.1 - 9.3e-21 74.4 0.0 2.8e-20 72.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EEQ30372.1 - 2.3e-20 72.7 0.1 2.4e-09 37.4 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 EEQ30372.1 - 1e-17 65.5 0.0 1.4e-15 58.5 0.0 3.8 4 0 0 4 4 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EEQ30372.1 - 2.6e-17 63.0 0.0 1.5e-16 60.5 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EEQ30372.1 - 4.2e-08 32.9 0.2 1.4e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ30372.1 - 3.6e-06 26.7 0.0 8.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EEQ30372.1 - 0.00083 18.8 0.0 0.0024 17.3 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 EEQ30372.1 - 0.0011 19.9 0.0 0.0042 18.0 0.0 2.1 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain DUF1233 PF06806.12 EEQ30372.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative excisionase (DUF1233) DUF2460 PF09343.10 EEQ30375.1 - 0.077 12.5 0.7 0.1 12.1 0.7 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) ATG2_CAD PF13329.6 EEQ30376.1 - 1.1e-45 155.1 0.2 4e-45 153.3 0.2 2.1 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EEQ30376.1 - 7.9e-29 99.9 0.4 2.9e-28 98.1 0.1 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EEQ30376.1 - 0.0025 17.6 0.0 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 EEQ30376.1 - 0.038 13.8 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal DUF4055 PF13264.6 EEQ30376.1 - 0.1 12.8 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) A_deaminase PF00962.22 EEQ30377.1 - 7.2e-22 78.1 0.0 1.1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Ank_2 PF12796.7 EEQ30380.1 - 2.1e-26 92.3 10.6 4.6e-09 36.7 0.1 4.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EEQ30380.1 - 5.8e-19 67.6 3.5 0.00063 20.1 0.0 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EEQ30380.1 - 2.9e-18 65.7 2.6 0.0001 22.5 0.1 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ30380.1 - 1.1e-17 62.2 3.5 0.00077 19.7 0.0 7.2 8 0 0 8 8 7 4 Ankyrin repeat Ank_4 PF13637.6 EEQ30380.1 - 3.7e-15 56.1 2.6 0.00012 22.5 0.0 4.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.12 EEQ30380.1 - 6.6e-09 35.9 0.3 2.5e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Helo_like_N PF17111.5 EEQ30380.1 - 6.5e-06 25.7 1.4 1.6e-05 24.4 1.3 1.7 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 EEQ30380.1 - 0.0001 22.7 0.1 0.00057 20.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EEQ30380.1 - 0.013 15.7 0.0 0.051 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEQ30380.1 - 0.055 13.9 0.1 0.25 11.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EEQ30380.1 - 0.14 12.6 0.0 2.2 8.7 0.0 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L20 PF00453.18 EEQ30380.1 - 0.42 10.7 2.1 0.61 10.2 0.8 1.9 2 0 0 2 2 2 0 Ribosomal protein L20 APH PF01636.23 EEQ30381.1 - 2.9e-10 40.5 0.0 1.5e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ30381.1 - 0.057 12.3 0.3 0.14 11.0 0.0 1.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) Ribosomal_S17 PF00366.20 EEQ30383.1 - 1.9e-14 53.5 0.9 3.1e-14 52.8 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 AAA PF00004.29 EEQ30384.1 - 1.5e-36 125.7 0.0 2.3e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EEQ30384.1 - 3.1e-10 39.9 0.1 4.3e-08 33.0 0.0 3.3 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 EEQ30384.1 - 4.8e-05 23.6 1.0 0.00049 20.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EEQ30384.1 - 9.4e-05 22.6 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EEQ30384.1 - 9.5e-05 22.2 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEQ30384.1 - 0.00037 20.9 1.1 0.0022 18.4 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EEQ30384.1 - 0.0024 17.9 0.1 0.0076 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EEQ30384.1 - 0.0033 16.7 0.0 0.0064 15.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EEQ30384.1 - 0.0039 16.9 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEQ30384.1 - 0.0048 16.3 0.1 0.0097 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EEQ30384.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EEQ30384.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ30384.1 - 0.042 14.4 0.0 0.13 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEQ30384.1 - 0.048 13.2 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EEQ30384.1 - 0.075 13.0 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 EEQ30384.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EEQ30384.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EEQ30384.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EEQ30384.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EEQ30384.1 - 0.15 11.4 0.0 5.5 6.3 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 EEQ30384.1 - 0.82 9.9 3.1 0.87 9.8 0.1 2.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EEQ30385.1 - 9.9e-05 22.4 0.3 0.18 11.9 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Sde2_N_Ubi PF13019.6 EEQ30386.1 - 1.3e-67 226.8 0.1 1.3e-67 226.8 0.1 1.5 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Cep57_MT_bd PF06657.13 EEQ30386.1 - 0.2 12.1 1.9 0.41 11.1 1.9 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 S10_plectin PF03501.15 EEQ30387.1 - 1.2e-40 137.5 0.1 1.6e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M20 PF01546.28 EEQ30388.1 - 9.4e-29 100.6 0.2 1.3e-28 100.1 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEQ30388.1 - 2.4e-06 27.4 0.0 6.4e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EEQ30388.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 HIT PF01230.23 EEQ30389.1 - 2.7e-17 63.3 0.0 3.7e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EEQ30389.1 - 3.1e-08 34.1 0.0 3.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CRAL_TRIO PF00650.20 EEQ30390.1 - 2.1e-40 138.0 0.0 8.2e-40 136.1 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ30390.1 - 5.8e-14 52.0 0.2 1.7e-13 50.6 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEQ30390.1 - 3.6e-06 27.2 0.0 6.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.10 EEQ30391.1 - 4.6e-30 103.2 2.4 6.7e-30 102.7 2.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Aminopep PF10023.9 EEQ30391.1 - 0.057 12.8 0.5 0.076 12.4 0.5 1.1 1 0 0 1 1 1 0 Putative aminopeptidase CENP-B_dimeris PF09026.10 EEQ30392.1 - 6.2e-06 26.5 1.8 7.2e-06 26.3 1.8 1.1 1 0 0 1 1 1 1 Centromere protein B dimerisation domain FAM176 PF14851.6 EEQ30392.1 - 0.041 13.5 0.4 0.047 13.3 0.4 1.1 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EEQ30392.1 - 0.13 11.5 5.0 0.16 11.3 5.0 1.1 1 0 0 1 1 1 0 NOA36 protein UCH PF00443.29 EEQ30393.1 - 1.9e-51 175.0 0.0 2.5e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ30393.1 - 4.4e-16 59.4 4.3 4.6e-13 49.4 4.3 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EEQ30393.1 - 0.00014 22.2 2.3 0.00016 22.0 0.2 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DUF3435 PF11917.8 EEQ30394.1 - 2.9e-08 33.1 0.3 3.7e-08 32.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) adh_short PF00106.25 EEQ30395.1 - 1.7e-22 79.9 0.0 2.8e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ30395.1 - 4.6e-15 55.8 0.0 2.2e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ30395.1 - 1.9e-05 24.7 0.0 2.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Rhomboid PF01694.22 EEQ30396.1 - 2.9e-11 43.6 6.9 2.9e-11 43.6 6.9 1.5 2 0 0 2 2 2 1 Rhomboid family Ytp1 PF10355.9 EEQ30397.1 - 3.6e-117 390.5 7.2 3.6e-117 390.5 7.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EEQ30397.1 - 8.2e-30 102.7 6.0 8.2e-30 102.7 6.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) Metallophos PF00149.28 EEQ30401.1 - 2.5e-08 34.7 1.2 3.9e-08 34.0 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEQ30401.1 - 4.2e-05 23.8 0.1 0.39 10.9 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Cob_adeno_trans PF01923.18 EEQ30401.1 - 0.18 11.9 0.1 1.6 8.9 0.0 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase RTA1 PF04479.13 EEQ30402.1 - 2.8e-77 259.0 3.6 2.8e-77 259.0 3.6 1.4 2 0 0 2 2 2 1 RTA1 like protein Gaa1 PF04114.14 EEQ30404.1 - 5.1e-180 599.8 6.4 6.1e-180 599.5 6.4 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.27 EEQ30405.1 - 4.2e-09 36.9 0.1 9.4e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EEQ30405.1 - 0.00025 20.6 0.1 0.00051 19.6 0.1 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Methyltransf_31 PF13847.6 EEQ30406.1 - 2.2e-13 50.2 0.0 2.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ30406.1 - 1.3e-12 48.3 0.0 2.7e-12 47.3 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ30406.1 - 2.9e-12 47.1 0.0 5.8e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ30406.1 - 3.7e-12 46.7 0.0 9e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ30406.1 - 9.9e-12 45.0 0.0 1.2e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ30406.1 - 8e-09 35.2 0.0 1.5e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EEQ30406.1 - 0.00062 19.8 0.0 0.00077 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EEQ30406.1 - 0.0045 16.6 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Pox_MCEL PF03291.16 EEQ30406.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme DREV PF05219.12 EEQ30406.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 EEQ30406.1 - 0.03 14.1 0.0 0.055 13.2 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EEQ30406.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GMC_oxred_N PF00732.19 EEQ30407.1 - 7.4e-60 202.8 0.0 1e-59 202.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EEQ30407.1 - 5.8e-35 120.9 0.0 9e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EEQ30407.1 - 1.1e-05 25.2 0.0 0.0028 17.3 0.0 3.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ30407.1 - 0.00018 21.7 0.0 0.00056 20.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EEQ30407.1 - 0.00025 20.2 0.1 0.00036 19.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EEQ30407.1 - 0.00029 20.0 0.0 0.031 13.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EEQ30407.1 - 0.0017 17.7 0.2 0.0045 16.2 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EEQ30407.1 - 0.0089 15.3 0.1 1 8.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ30407.1 - 0.047 14.3 0.1 18 6.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEQ30407.1 - 0.2 10.3 0.0 0.38 9.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Epimerase PF01370.21 EEQ30410.1 - 2e-14 53.7 0.1 6.6e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EEQ30410.1 - 5.4e-12 46.0 0.0 1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ30410.1 - 1.3e-11 44.5 0.0 3.2e-11 43.3 0.0 1.6 1 1 1 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 EEQ30410.1 - 2.4e-11 43.2 0.1 4.2e-11 42.4 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EEQ30410.1 - 1.2e-07 31.5 0.3 7.2e-07 28.9 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EEQ30410.1 - 9.4e-05 21.9 0.2 0.00023 20.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EEQ30410.1 - 0.00012 21.4 0.2 0.015 14.5 0.0 2.7 1 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EEQ30410.1 - 0.00066 18.9 0.0 0.058 12.5 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.6 EEQ30410.1 - 0.0042 16.7 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HIM1 PF08732.10 EEQ30410.1 - 0.026 14.0 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 HIM1 DDE_Tnp_1_3 PF13612.6 EEQ30410.1 - 0.069 13.2 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Transposase DDE domain KR PF08659.10 EEQ30410.1 - 0.16 11.9 0.0 2.4 8.1 0.0 2.3 3 0 0 3 3 3 0 KR domain HEM4 PF02602.15 EEQ30411.1 - 2.1e-36 125.5 0.0 1.9e-29 102.7 0.0 2.0 2 0 0 2 2 2 2 Uroporphyrinogen-III synthase HemD Pkinase PF00069.25 EEQ30412.1 - 4.5e-67 226.2 0.0 5.5e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30412.1 - 8.4e-32 110.5 0.0 1.1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ30412.1 - 0.00053 19.4 0.2 0.0009 18.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EEQ30412.1 - 0.002 17.1 0.1 0.0031 16.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EEQ30412.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EEQ30412.1 - 0.03 14.3 0.2 0.086 12.7 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family S_100 PF01023.19 EEQ30412.1 - 0.035 13.8 0.3 0.11 12.2 0.3 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Seadorna_VP7 PF07387.11 EEQ30412.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sec23_trunk PF04811.15 EEQ30415.1 - 1.8e-71 240.5 0.0 2.9e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EEQ30415.1 - 1.4e-22 79.4 0.0 8.6e-22 76.9 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EEQ30415.1 - 1.3e-16 61.1 0.0 3.2e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EEQ30415.1 - 2.4e-16 59.5 3.7 4.5e-16 58.6 3.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EEQ30415.1 - 8.6e-07 28.8 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EEQ30415.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Kinesin PF00225.23 EEQ30416.1 - 7.5e-75 251.9 1.2 2.7e-74 250.1 1.2 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ30416.1 - 1.9e-13 50.6 0.1 5.1e-12 46.0 0.1 2.5 1 1 0 1 1 1 1 Microtubule binding HHH PF00633.23 EEQ30416.1 - 0.0016 18.2 0.0 0.41 10.6 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF4656 PF15551.6 EEQ30416.1 - 0.017 14.7 0.1 0.04 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) HHH_3 PF12836.7 EEQ30416.1 - 0.024 14.9 0.0 0.45 10.8 0.0 2.6 1 1 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EEQ30416.1 - 0.041 14.5 0.1 6 7.6 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_14 PF13428.6 EEQ30416.1 - 0.085 13.7 0.0 0.4 11.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 EEQ30417.1 - 6.7e-25 87.7 72.4 4.1e-20 72.0 37.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HRI1 PF16815.5 EEQ30418.1 - 1.5e-26 93.5 0.1 2e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 Protein HRI1 Peptidase_M43 PF05572.13 EEQ30419.1 - 2.3e-16 60.1 2.9 6.2e-13 48.9 2.9 2.2 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EEQ30419.1 - 0.00031 21.0 0.1 0.0005 20.3 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EEQ30419.1 - 0.0016 18.4 0.4 0.0044 16.9 0.4 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EEQ30419.1 - 0.0019 18.7 0.0 0.0038 17.7 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EEQ30419.1 - 0.1 12.5 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Matrixin AIM24 PF01987.17 EEQ30420.1 - 1.9e-48 165.0 0.1 2.3e-48 164.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ABC_membrane PF00664.23 EEQ30421.1 - 8.7e-43 146.9 12.1 1.1e-42 146.6 12.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ30421.1 - 9.3e-34 116.9 0.0 1.6e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EEQ30421.1 - 7.7e-06 25.5 0.1 0.00012 21.6 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EEQ30421.1 - 0.00013 22.3 0.0 0.00042 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEQ30421.1 - 0.00042 20.8 0.0 0.00094 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EEQ30421.1 - 0.00083 19.2 0.1 0.012 15.5 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EEQ30421.1 - 0.011 15.5 0.2 0.033 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EEQ30421.1 - 0.016 14.9 0.1 0.039 13.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EEQ30421.1 - 0.018 15.1 0.1 0.36 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EEQ30421.1 - 0.023 15.2 0.0 0.058 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EEQ30421.1 - 0.028 14.3 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 EEQ30421.1 - 0.034 14.7 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EEQ30421.1 - 0.039 13.9 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase Cytidylate_kin PF02224.18 EEQ30421.1 - 0.044 13.5 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase ATP-synt_ab PF00006.25 EEQ30421.1 - 0.049 13.3 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 EEQ30421.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EEQ30421.1 - 0.06 13.4 0.0 0.19 11.8 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EEQ30421.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EEQ30421.1 - 0.063 13.7 0.0 0.54 10.7 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EEQ30421.1 - 0.071 13.3 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain GPAT_N PF14829.6 EEQ30421.1 - 0.091 12.8 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal DUF2847 PF11009.8 EEQ30421.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) IstB_IS21 PF01695.17 EEQ30421.1 - 0.23 11.2 2.6 13 5.5 0.0 3.2 4 0 0 4 4 3 0 IstB-like ATP binding protein DUF2013 PF09431.10 EEQ30422.1 - 9.5e-51 171.6 0.7 9.5e-51 171.6 0.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Glyco_hydro_17 PF00332.18 EEQ30423.1 - 1.2e-06 28.4 1.0 2.3e-06 27.4 0.5 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.21 EEQ30424.1 - 1e-35 123.6 0.0 1.3e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PAS_11 PF14598.6 EEQ30424.1 - 0.12 12.5 0.0 0.99 9.6 0.0 2.2 2 0 0 2 2 2 0 PAS domain RestrictionSfiI PF11487.8 EEQ30424.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI Glucan_synthase PF02364.15 EEQ30425.1 - 0 1372.5 0.0 0 1372.0 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EEQ30425.1 - 2.3e-43 147.6 0.2 7.1e-43 146.0 0.2 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.14 EEQ30427.1 - 3.3e-131 437.3 9.3 4.1e-131 436.9 9.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EEQ30427.1 - 4.3e-25 88.2 2.1 1.4e-24 86.6 2.1 2.0 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EEQ30427.1 - 0.0094 15.1 2.9 0.042 13.0 2.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain SprT-like PF10263.9 EEQ30428.1 - 8.5e-38 128.7 0.1 1.7e-37 127.7 0.1 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EEQ30428.1 - 1.1e-05 25.3 5.9 2.4e-05 24.1 5.9 1.7 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EEQ30428.1 - 0.49 10.6 5.8 1.2 9.3 3.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Mog1 PF04603.12 EEQ30429.1 - 3.4e-32 111.7 0.0 5.3e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein NYN PF01936.18 EEQ30430.1 - 0.00062 20.3 0.0 0.0035 17.8 0.0 2.1 1 1 0 1 1 1 1 NYN domain HSP9_HSP12 PF04119.12 EEQ30431.1 - 7.3e-27 93.5 4.6 1.1e-26 92.9 3.9 1.6 2 0 0 2 2 2 1 Heat shock protein 9/12 COG6 PF06419.11 EEQ30432.1 - 1.2e-212 707.5 2.9 1.4e-212 707.4 2.9 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 HeLo PF14479.6 EEQ30432.1 - 0.02 14.7 0.4 0.84 9.4 0.0 2.9 3 0 0 3 3 3 0 Prion-inhibition and propagation MAP65_ASE1 PF03999.12 EEQ30432.1 - 0.062 12.0 0.9 0.12 11.0 0.9 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NIF3 PF01784.18 EEQ30433.1 - 4.7e-48 163.9 0.0 1e-35 123.6 0.0 2.1 2 0 0 2 2 2 2 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 EEQ30434.1 - 5.9e-19 68.1 0.0 1.7e-18 66.6 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein Redoxin PF08534.10 EEQ30435.1 - 4.5e-29 101.1 0.0 5.6e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EEQ30435.1 - 4.4e-06 26.6 0.0 6.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Response_reg PF00072.24 EEQ30436.1 - 3e-23 82.1 0.0 5.3e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HSF_DNA-bind PF00447.17 EEQ30436.1 - 1.1e-08 35.6 0.2 0.0024 18.5 0.0 2.8 1 1 1 2 2 2 2 HSF-type DNA-binding CdiA_C PF18451.1 EEQ30436.1 - 0.15 12.3 0.5 0.37 11.0 0.0 1.9 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain UPF0506 PF11703.8 EEQ30437.1 - 0.043 14.2 3.5 0.043 14.2 3.5 3.6 2 1 1 3 3 3 0 UPF0506 W2 PF02020.18 EEQ30438.1 - 7.1e-18 64.5 4.0 7.1e-18 64.5 4.0 4.1 5 0 0 5 5 5 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EEQ30438.1 - 3.3e-11 42.4 10.7 7.2e-06 25.5 4.3 3.6 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EEQ30438.1 - 0.00021 21.0 6.7 0.01 15.6 2.7 2.6 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EEQ30438.1 - 0.0036 15.5 0.9 0.0059 14.8 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EEQ30438.1 - 0.021 13.8 0.5 0.069 12.1 0.5 1.7 1 1 0 1 1 1 0 L-fucokinase NTP_transferase PF00483.23 EEQ30438.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyl transferase SDA1 PF05285.12 EEQ30438.1 - 8.5 5.7 11.6 16 4.8 11.6 1.4 1 0 0 1 1 1 0 SDA1 IBR PF01485.21 EEQ30439.1 - 2.9e-22 78.7 49.1 2.6e-12 46.8 5.2 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EEQ30439.1 - 0.00035 20.9 8.9 0.00035 20.9 8.9 4.0 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 EEQ30439.1 - 0.00056 19.7 5.9 0.00056 19.7 5.9 4.4 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.8 EEQ30439.1 - 0.0011 19.5 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-C3HC4_2 PF13923.6 EEQ30439.1 - 0.0023 17.8 5.9 0.0023 17.8 5.9 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ30439.1 - 0.0093 15.9 10.1 0.0093 15.9 10.1 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEQ30439.1 - 0.021 14.8 4.9 0.021 14.8 4.9 3.9 3 1 0 3 3 3 0 RING-type zinc-finger Mito_carr PF00153.27 EEQ30440.1 - 9.9e-66 217.7 5.5 5.6e-22 77.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ30440.1 - 0.8 8.8 4.1 1.7 7.7 0.3 2.9 2 1 2 4 4 4 0 Gammaproteobacterial serine protease tRNA-synt_1 PF00133.22 EEQ30441.1 - 6.2e-36 123.8 0.0 2.1e-25 89.0 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EEQ30441.1 - 1e-15 57.4 0.0 3.7e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EEQ30441.1 - 1.1e-10 41.7 0.1 3.1e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EEQ30441.1 - 3.2e-07 30.0 0.0 7.1e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EEQ30441.1 - 0.028 13.3 0.0 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) CsgA PF17334.2 EEQ30441.1 - 0.41 11.4 1.5 5.9 7.7 0.0 3.3 4 0 0 4 4 4 0 Minor curli fiber component A L51_S25_CI-B8 PF05047.16 EEQ30442.1 - 3.9e-15 55.5 0.0 6.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1751 PF08551.10 EEQ30443.1 - 9.1e-29 100.0 0.8 1.9e-28 98.9 0.8 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EEQ30443.1 - 4.8e-05 23.4 10.4 0.00011 22.2 10.4 1.6 1 0 0 1 1 1 1 Rhomboid family WD40 PF00400.32 EEQ30445.1 - 3.9e-06 27.5 0.2 0.68 10.9 0.0 5.7 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ30445.1 - 5.5e-06 26.6 0.5 0.0054 17.0 0.0 5.1 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ30445.1 - 0.065 13.1 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EEQ30445.1 - 0.18 11.8 1.9 65 3.6 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_alt PF14077.6 EEQ30446.1 - 0.013 15.3 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif SlyX PF04102.12 EEQ30446.1 - 0.014 16.0 0.4 9.7 6.9 0.0 3.5 3 1 1 4 4 4 0 SlyX Shugoshin_N PF07558.11 EEQ30446.1 - 0.034 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CdvA PF18822.1 EEQ30446.1 - 0.044 13.6 0.2 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Troponin PF00992.20 EEQ30446.1 - 0.083 13.2 4.7 0.092 13.0 1.4 2.1 2 0 0 2 2 2 0 Troponin Jnk-SapK_ap_N PF09744.9 EEQ30446.1 - 1.2 9.4 7.3 2.7 8.2 7.1 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.21 EEQ30446.1 - 4 7.6 8.0 4.5 7.4 5.0 2.5 2 1 0 2 2 2 0 bZIP transcription factor Chorismate_bind PF00425.18 EEQ30447.1 - 4.8e-91 304.9 0.0 6.8e-91 304.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EEQ30447.1 - 4.2e-28 98.3 0.0 6e-25 88.1 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region ENTH PF01417.20 EEQ30448.1 - 1.1e-48 164.4 0.0 1.6e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 EEQ30448.1 - 3.1e-07 30.7 41.3 3.1e-07 30.7 41.3 5.5 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) ANTH PF07651.16 EEQ30448.1 - 1.3e-05 24.3 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 EEQ30448.1 - 0.0026 17.6 5.8 0.061 13.3 0.7 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF4264 PF14084.6 EEQ30448.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) DUF572 PF04502.13 EEQ30448.1 - 0.32 10.6 15.1 1.7 8.2 6.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Pkinase PF00069.25 EEQ30449.1 - 9.6e-22 77.6 0.0 1.1e-09 38.1 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30449.1 - 1.5e-08 34.3 0.0 0.00088 18.6 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase EABR PF12180.8 EEQ30449.1 - 0.031 13.9 0.1 0.066 12.8 0.1 1.5 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Kinase-like PF14531.6 EEQ30449.1 - 0.19 11.0 0.2 8.3 5.6 0.1 2.5 3 0 0 3 3 3 0 Kinase-like Cnd1 PF12717.7 EEQ30450.1 - 7.4e-07 29.3 0.0 0.0087 16.1 0.0 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EEQ30450.1 - 1.4e-06 28.1 1.3 0.00053 19.6 0.0 2.6 3 0 0 3 3 2 2 CLASP N terminal HEAT PF02985.22 EEQ30450.1 - 1.3e-05 25.0 0.1 2 8.9 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.20 EEQ30450.1 - 2.3e-05 23.2 0.2 6.5e-05 21.7 0.2 2.0 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 EEQ30450.1 - 0.00024 21.4 0.2 0.03 14.7 0.2 3.5 2 1 2 4 4 4 1 HEAT repeats TAN PF11640.8 EEQ30450.1 - 0.00081 19.5 1.0 0.0072 16.5 0.0 2.8 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Macoilin PF09726.9 EEQ30450.1 - 0.011 14.3 4.6 0.014 14.0 0.0 2.1 2 0 0 2 2 2 0 Macoilin family Spc7 PF08317.11 EEQ30450.1 - 0.08 11.8 9.7 0.18 10.7 9.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Proteasom_PSMB PF10508.9 EEQ30450.1 - 0.081 11.4 0.1 8.2 4.8 0.1 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit MMS19_N PF14500.6 EEQ30450.1 - 0.11 12.0 0.1 5.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DCB PF16213.5 EEQ30450.1 - 0.12 12.1 0.1 0.89 9.2 0.0 2.4 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 G-gamma PF00631.22 EEQ30450.1 - 0.16 12.0 0.9 0.77 9.8 0.9 2.2 1 0 0 1 1 1 0 GGL domain Golgin_A5 PF09787.9 EEQ30450.1 - 0.64 9.4 10.5 1.6 8.1 10.5 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 UPF0242 PF06785.11 EEQ30450.1 - 0.79 9.8 9.0 2.2 8.3 9.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COG5 PF10392.9 EEQ30450.1 - 1.9 8.7 6.4 1.6 8.9 4.6 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Fez1 PF06818.15 EEQ30450.1 - 3.2 8.1 14.3 0.34 11.3 8.9 2.0 2 0 0 2 2 2 0 Fez1 Exonuc_VII_L PF02601.15 EEQ30450.1 - 3.9 6.9 10.3 2 7.9 4.6 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF812 PF05667.11 EEQ30450.1 - 4.6 6.0 14.9 4.2 6.2 9.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 EEQ30450.1 - 6.8 5.9 13.4 0.59 9.4 7.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EEQ30450.1 - 6.9 5.7 7.0 13 4.7 7.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EEQ30450.1 - 8.6 6.4 15.5 21 5.2 15.5 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ribosomal_L7Ae PF01248.26 EEQ30451.1 - 2.7e-21 75.1 0.4 4.4e-21 74.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRP36 PF06102.12 EEQ30451.1 - 0.0082 16.1 4.0 0.0092 16.0 0.4 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 DUF2841 PF11001.8 EEQ30452.1 - 1.3e-47 161.0 0.0 2.1e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Clat_adaptor_s PF01217.20 EEQ30457.1 - 5.7e-31 107.3 0.0 1.2e-30 106.3 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.23 EEQ30458.1 - 3.5e-18 65.7 0.0 5.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EEQ30458.1 - 3.5e-07 29.8 0.0 5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EEQ30458.1 - 7.1e-06 26.2 0.0 0.00049 20.2 0.1 2.2 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 EEQ30458.1 - 2.9e-05 23.7 0.0 0.0001 21.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ30458.1 - 0.00018 21.5 0.3 0.0006 19.8 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EEQ30458.1 - 0.0003 20.3 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EEQ30458.1 - 0.00087 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 EEQ30458.1 - 0.0069 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Septin TniB PF05621.11 EEQ30458.1 - 0.15 11.4 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 EEQ30458.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.32 EEQ30459.1 - 7.3e-41 137.4 17.0 3.3e-06 27.7 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EEQ30459.1 - 2.2e-10 40.3 0.1 5.1e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ30459.1 - 2.9e-10 39.8 0.2 6e-10 38.8 0.2 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EEQ30459.1 - 0.00024 21.3 1.1 8.2 6.8 0.0 4.5 2 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ30459.1 - 0.0011 17.8 5.4 7 5.2 0.2 5.1 4 2 1 6 6 6 2 Nucleoporin Nup120/160 F-box_4 PF15966.5 EEQ30459.1 - 0.0019 18.1 0.0 0.0056 16.5 0.0 1.8 1 0 0 1 1 1 1 F-box FliG_C PF01706.16 EEQ30459.1 - 0.073 13.3 0.0 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 FliG C-terminal domain AcylCoA_DH_N PF12418.8 EEQ30459.1 - 0.16 12.0 0.2 0.48 10.5 0.2 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal SRP9-21 PF05486.12 EEQ30459.1 - 0.37 11.2 2.5 6.8 7.2 0.0 3.9 4 1 0 5 5 5 0 Signal recognition particle 9 kDa protein (SRP9) HORMA PF02301.18 EEQ30460.1 - 6.5e-57 192.5 0.0 1e-56 191.9 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 EEQ30460.1 - 0.0013 18.6 10.3 0.0032 17.3 10.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEQ30460.1 - 0.022 14.3 2.9 0.064 12.8 2.9 1.8 1 0 0 1 1 1 0 PHD-finger Nuc_sug_transp PF04142.15 EEQ30462.1 - 1.4e-78 264.3 9.8 1.8e-78 263.9 9.8 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EEQ30462.1 - 0.012 15.8 12.1 0.012 15.8 12.1 2.6 2 1 0 2 2 2 0 EamA-like transporter family EmrE PF13536.6 EEQ30462.1 - 0.8 9.2 17.5 0.31 10.6 2.2 2.5 2 1 0 2 2 2 0 Putative multidrug resistance efflux transporter Sec63 PF02889.16 EEQ30463.1 - 1.2e-29 103.2 0.0 2.1e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EEQ30463.1 - 1.9e-27 96.1 0.2 4.4e-27 95.0 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EEQ30463.1 - 2.3e-13 50.5 0.1 6.6e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ30463.1 - 7.9e-08 32.6 0.0 7.5e-07 29.5 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EEQ30463.1 - 0.0035 17.7 0.1 0.018 15.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ30463.1 - 0.006 16.9 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 EEQ30463.1 - 0.038 14.6 0.1 0.089 13.4 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain AAA_30 PF13604.6 EEQ30463.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EEQ30463.1 - 0.088 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) LRR_6 PF13516.6 EEQ30464.1 - 0.0004 20.2 0.9 7 7.0 0.1 3.9 3 0 0 3 3 3 2 Leucine Rich repeat Acid_PPase PF12689.7 EEQ30465.1 - 6.8e-70 234.3 0.0 7.9e-70 234.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hexapep PF00132.24 EEQ30466.1 - 1.7e-09 37.0 8.3 0.0013 18.4 3.2 4.1 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EEQ30466.1 - 0.00051 19.7 7.4 0.02 14.7 2.5 3.6 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase TPR_MLP1_2 PF07926.12 EEQ30467.1 - 8.8e-38 129.3 29.8 8.8e-38 129.3 29.8 18.0 8 6 7 16 16 16 6 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 EEQ30467.1 - 0.0068 16.5 2.7 0.0068 16.5 2.7 14.0 1 1 11 13 13 13 1 Ciliary rootlet component, centrosome cohesion Cbl_N PF02262.16 EEQ30467.1 - 0.021 14.8 4.2 0.5 10.4 0.2 4.7 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Tom37 PF10568.9 EEQ30467.1 - 2.6 8.4 5.1 30 5.0 0.0 3.9 3 0 0 3 3 3 0 Outer mitochondrial membrane transport complex protein Wzy_C_2 PF11846.8 EEQ30467.1 - 6 6.7 7.4 0.43 10.5 0.2 2.8 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TFA2_Winged_2 PF18121.1 EEQ30468.1 - 1.4e-22 79.1 1.4 2.2e-22 78.5 0.3 2.0 3 0 0 3 3 3 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EEQ30468.1 - 1.5e-22 79.6 0.1 2.3e-21 75.8 0.0 2.6 2 1 0 2 2 2 1 TFIIE beta subunit core domain DUF1631 PF07793.11 EEQ30468.1 - 0.052 12.0 4.1 0.012 14.1 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) DHBP_synthase PF00926.19 EEQ30469.1 - 1.1e-81 272.9 0.0 1.3e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase F-box-like PF12937.7 EEQ30470.1 - 7.4e-08 32.2 1.5 1.5e-07 31.2 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EEQ30470.1 - 1.7e-07 30.9 0.2 1.7e-07 30.9 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EEQ30470.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 F-box Pkinase PF00069.25 EEQ30471.1 - 1.9e-60 204.5 0.0 3.4e-60 203.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30471.1 - 2.3e-25 89.3 0.0 3.3e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ30471.1 - 2.5e-09 36.9 0.0 3.3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ30471.1 - 0.0033 16.8 0.0 0.025 13.9 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 EEQ30472.1 - 7.1e-49 165.1 0.0 8.8e-49 164.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEQ30472.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EEQ30472.1 - 0.0026 17.4 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EEQ30472.1 - 0.0062 16.4 0.2 0.012 15.5 0.1 1.5 1 1 0 1 1 1 1 UEV domain UFC1 PF08694.11 EEQ30472.1 - 0.024 14.3 0.1 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 YjbT PF17089.5 EEQ30472.1 - 0.16 12.0 0.2 0.34 10.9 0.1 1.5 2 0 0 2 2 2 0 Uncharacterised protein family Nucleos_tra2_C PF07662.13 EEQ30474.1 - 1.1e-61 208.2 0.8 1.1e-61 208.2 0.8 3.7 4 2 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EEQ30474.1 - 2.3e-23 82.6 4.4 2.3e-23 82.6 4.4 3.1 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Prenyltransf PF01255.19 EEQ30476.1 - 2.2e-21 76.4 0.0 3.2e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase UbiA PF01040.18 EEQ30477.1 - 2.6e-19 69.5 7.2 3.1e-19 69.3 7.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family FtsX PF02687.21 EEQ30477.1 - 0.0077 16.7 1.1 0.03 14.8 1.1 1.9 1 1 0 1 1 1 1 FtsX-like permease family Cytochrome_P460 PF16694.5 EEQ30477.1 - 0.084 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome P460 Glyco_transf_20 PF00982.21 EEQ30478.1 - 1e-199 664.1 0.0 1.2e-199 663.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EEQ30478.1 - 0.019 14.6 0.5 0.039 13.6 0.1 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain BLACT_WH PF17778.1 EEQ30479.1 - 9.5e-19 67.1 0.0 1.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 EEQ30479.1 - 5.5e-12 46.1 4.5 5.3e-11 42.9 4.5 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EEQ30479.1 - 2e-06 27.5 0.6 3.2e-06 26.8 0.6 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain YmzC PF14157.6 EEQ30479.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 YmzC-like protein Aconitase PF00330.20 EEQ30480.1 - 1.5e-148 495.7 0.0 1.8e-148 495.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEQ30480.1 - 1.5e-42 145.1 0.0 2.4e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Abhydrolase_2 PF02230.16 EEQ30481.1 - 9.9e-25 87.6 0.0 1.4e-17 64.2 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EEQ30481.1 - 0.00047 19.7 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EEQ30481.1 - 0.023 13.9 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 zf-C2H2_jaz PF12171.8 EEQ30482.1 - 4.9e-10 39.4 4.0 4.9e-10 39.4 4.0 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EEQ30482.1 - 0.015 15.6 1.5 0.024 15.0 1.5 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EEQ30482.1 - 0.045 14.2 2.0 0.045 14.2 2.0 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-U1 PF06220.12 EEQ30482.1 - 0.14 12.0 1.5 0.14 11.9 0.5 1.6 2 0 0 2 2 2 0 U1 zinc finger zf-C2H2_4 PF13894.6 EEQ30482.1 - 0.17 12.8 0.1 0.17 12.8 0.1 2.3 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EEQ30482.1 - 1.6 8.8 7.1 0.2 11.7 1.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Mito_carr PF00153.27 EEQ30483.1 - 1.1e-39 134.3 3.3 4.9e-15 55.2 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Heliorhodopsin PF18761.1 EEQ30483.1 - 0.036 13.4 0.1 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Heliorhodopsin SNF2_N PF00176.23 EEQ30484.1 - 4.3e-57 193.4 0.0 7e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EEQ30484.1 - 4.7e-54 183.3 0.1 1e-53 182.2 0.1 1.6 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 EEQ30484.1 - 1.1e-15 57.9 0.0 4.1e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ30484.1 - 1.7e-08 34.7 0.0 3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EEQ30484.1 - 0.00021 20.6 0.0 0.0011 18.2 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Vac14_Fig4_bd PF11916.8 EEQ30485.1 - 7.2e-82 273.4 9.8 7.4e-82 273.3 7.3 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EEQ30485.1 - 2.7e-44 149.7 0.1 2.4e-40 137.0 0.0 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EEQ30485.1 - 8.1e-09 35.8 2.4 0.058 13.9 0.1 5.8 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 EEQ30485.1 - 3.2e-06 26.9 0.2 0.44 10.9 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 EEQ30485.1 - 0.0015 18.6 4.2 0.055 13.5 0.2 3.9 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EEQ30485.1 - 0.0077 16.2 0.0 51 4.1 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 EEQ30485.1 - 0.12 12.3 0.0 22 4.9 0.0 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) Glyco_hydro_47 PF01532.20 EEQ30486.1 - 1.5e-178 594.4 0.0 1.8e-178 594.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APG9 PF04109.16 EEQ30487.1 - 4.2e-156 520.7 17.5 4.9e-149 497.4 9.6 2.0 1 1 1 2 2 2 2 Autophagy protein Apg9 RasGAP PF00616.19 EEQ30489.1 - 3.1e-32 112.0 0.0 1.1e-20 74.2 0.0 3.5 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EEQ30489.1 - 2.5e-07 30.9 0.1 4.4e-06 26.9 0.1 2.6 2 1 0 2 2 2 1 C2 domain DGF-1_4 PF11024.8 EEQ30489.1 - 0.35 11.7 3.3 2.5 9.0 3.3 2.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 DNA_methylase PF00145.17 EEQ30490.1 - 4.5e-30 105.1 0.0 1.1e-29 103.9 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EEQ30490.1 - 0.00011 22.0 0.2 0.056 13.3 0.0 2.8 1 1 1 2 2 2 2 BAH domain WD40 PF00400.32 EEQ30491.1 - 4.1e-05 24.3 1.4 4.6 8.3 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat TTR-52 PF01060.23 EEQ30491.1 - 0.02 15.6 0.0 0.044 14.5 0.0 1.5 1 0 0 1 1 1 0 Transthyretin-like family UvrA_inter PF17760.1 EEQ30492.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 UvrA interaction domain COQ9 PF08511.11 EEQ30493.1 - 1.6e-25 88.6 0.1 3.5e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 COQ9 Ost5 PF05251.12 EEQ30494.1 - 0.042 14.1 1.9 0.042 14.1 1.9 2.1 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 AA_permease_2 PF13520.6 EEQ30495.1 - 4.7e-54 183.8 50.3 5.9e-54 183.5 50.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ30495.1 - 9e-22 77.3 44.1 1.2e-21 76.9 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease FmdA_AmdA PF03069.15 EEQ30496.1 - 9.4e-57 192.5 0.0 7.2e-33 113.9 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family LeuA_dimer PF08502.10 EEQ30496.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain RRM_1 PF00076.22 EEQ30498.1 - 1.4e-13 50.4 0.0 0.00091 19.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRD PF00874.20 EEQ30499.1 - 0.16 12.3 0.4 0.45 10.8 0.4 1.8 2 0 0 2 2 2 0 PRD domain RPT PF13446.6 EEQ30501.1 - 7.6e-50 166.7 0.8 5.2e-18 64.7 0.0 4.7 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 EEQ30501.1 - 1e-43 149.7 2.0 5.8e-43 147.2 2.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Microvir_H PF04687.12 EEQ30501.1 - 0.0064 15.9 0.4 0.012 15.1 0.4 1.3 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) UCH_1 PF13423.6 EEQ30501.1 - 0.0074 15.9 6.8 0.044 13.4 6.8 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 EEQ30501.1 - 0.0078 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 PUB domain CoA_trans PF01144.23 EEQ30502.1 - 7.4e-105 349.1 2.5 8.8e-65 218.1 0.7 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2370 PF10176.9 EEQ30504.1 - 2.7e-91 305.2 0.0 3.9e-91 304.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 EEQ30504.1 - 0.11 12.5 0.7 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) SKG6 PF08693.10 EEQ30506.1 - 6.2e-08 31.9 1.1 1.5e-07 30.7 1.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain WSC PF01822.19 EEQ30506.1 - 9.7e-08 32.1 6.4 1.8e-07 31.2 6.4 1.5 1 0 0 1 1 1 1 WSC domain LapA_dom PF06305.11 EEQ30506.1 - 0.064 13.1 0.1 0.064 13.1 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CDP-OH_P_transf PF01066.21 EEQ30508.1 - 1.9e-11 44.6 0.4 4.8e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.14 EEQ30509.1 - 2.7e-37 127.9 0.0 3.3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.25 EEQ30510.1 - 2.3e-30 105.9 0.0 1e-28 100.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EEQ30510.1 - 6.8e-16 58.2 0.1 1.3e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EEQ30510.1 - 8.2e-13 48.2 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EEQ30510.1 - 0.0017 18.4 0.0 0.004 17.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain Fungal_trans PF04082.18 EEQ30511.1 - 5.1e-20 71.6 0.9 1.3e-19 70.2 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ30511.1 - 1.1e-09 38.2 13.3 2.1e-09 37.4 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ndc1_Nup PF09531.10 EEQ30511.1 - 4.5 5.8 10.8 1.3 7.7 0.2 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Peptidase_M41 PF01434.18 EEQ30512.1 - 1.7e-67 227.0 0.0 3.8e-67 225.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EEQ30512.1 - 7.5e-42 142.9 0.0 2.1e-41 141.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ30512.1 - 7.9e-12 44.8 0.1 2.2e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EEQ30512.1 - 4.6e-09 36.6 0.1 4.6e-09 36.6 0.1 2.4 3 0 0 3 3 3 1 FtsH Extracellular AAA_5 PF07728.14 EEQ30512.1 - 0.0024 17.9 0.0 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEQ30512.1 - 0.0024 18.3 0.2 0.14 12.5 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EEQ30512.1 - 0.008 16.5 0.4 1.1 9.5 0.0 3.4 4 0 0 4 4 4 1 AAA domain RuvB_N PF05496.12 EEQ30512.1 - 0.019 14.7 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EEQ30512.1 - 0.02 14.1 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 EEQ30512.1 - 0.023 14.4 0.0 0.054 13.2 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EEQ30512.1 - 0.14 12.3 0.5 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_pol_Rpc4 PF05132.14 EEQ30512.1 - 0.24 11.8 6.2 0.1 13.0 0.3 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 AAA_11 PF13086.6 EEQ30512.1 - 0.74 9.6 10.9 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EEQ30512.1 - 1.8 9.0 5.1 2.1 8.8 0.0 3.2 3 1 1 4 4 4 0 AAA domain Presenilin PF01080.17 EEQ30512.1 - 6 5.5 5.8 10 4.8 5.8 1.3 1 0 0 1 1 1 0 Presenilin DUF1295 PF06966.12 EEQ30513.1 - 1e-39 136.4 7.9 1.4e-39 136.0 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EEQ30513.1 - 0.35 11.3 0.1 0.35 11.3 0.1 3.3 3 2 1 4 4 4 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.20 EEQ30514.1 - 3.9e-91 306.1 0.0 5e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EEQ30514.1 - 1e-14 54.6 0.0 2.3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Baculo_PEP_C PF04513.12 EEQ30515.1 - 0.0021 18.1 20.9 0.46 10.5 0.1 5.1 2 1 2 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Endonuc-PvuII PF09225.10 EEQ30515.1 - 0.088 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Restriction endonuclease PvuII DUF2746 PF10874.8 EEQ30515.1 - 0.27 11.7 4.5 2.4 8.7 0.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) Vac_Fusion PF02346.16 EEQ30515.1 - 0.28 10.8 7.6 0.79 9.4 0.1 4.5 5 0 0 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 NFRKB_winged PF14465.6 EEQ30515.1 - 0.43 10.8 2.4 3.8 7.7 0.2 3.6 2 2 1 3 3 3 0 NFRKB Winged Helix-like Focal_AT PF03623.13 EEQ30515.1 - 2.9 7.9 17.7 1.7 8.6 1.2 4.1 2 2 0 4 4 4 0 Focal adhesion targeting region TolA_bind_tri PF16331.5 EEQ30515.1 - 5.7 7.1 25.1 3.7 7.7 0.4 6.5 4 2 2 6 6 6 0 TolA binding protein trimerisation DUF389 PF04087.14 EEQ30517.1 - 0.12 12.4 0.2 0.2 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF389) Kdo PF06293.14 EEQ30518.1 - 1.6e-05 24.4 2.4 2.6e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEQ30518.1 - 0.0052 16.2 0.0 0.0052 16.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 EEQ30518.1 - 0.013 15.1 2.7 0.16 11.5 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 EEQ30518.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Borrelia_P83 PF05262.11 EEQ30518.1 - 1.7 7.1 16.3 2.5 6.5 16.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4149 PF13664.6 EEQ30519.1 - 2e-26 92.3 1.8 3.3e-26 91.6 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 EEQ30519.1 - 0.025 14.9 0.0 0.033 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Ku_PK_bind PF08785.11 EEQ30520.1 - 4.3e-37 126.9 0.3 1e-36 125.7 0.3 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 EEQ30520.1 - 1.9e-28 99.6 0.0 3.4e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EEQ30520.1 - 2.9e-07 30.4 0.0 1.2e-06 28.4 0.0 2.1 2 1 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 EEQ30520.1 - 0.0025 18.1 0.0 0.0066 16.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain PX PF00787.24 EEQ30521.1 - 8.8e-17 61.1 0.0 2.1e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 PX domain tRNA-synt_2 PF00152.20 EEQ30522.1 - 2.3e-66 224.0 0.1 3.1e-66 223.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ30522.1 - 4.9e-07 29.6 0.0 9.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Hydrolase_6 PF13344.6 EEQ30523.1 - 4.8e-24 84.4 0.0 1.5e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ30523.1 - 1.1e-14 54.2 0.0 1.1e-13 51.1 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EEQ30523.1 - 0.015 15.6 0.0 3.7 7.8 0.0 3.0 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ30523.1 - 0.12 12.5 0.0 5.1 7.1 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase F-box-like PF12937.7 EEQ30524.1 - 2.4e-10 40.1 0.3 9.1e-10 38.3 0.3 2.0 1 0 0 1 1 1 1 F-box-like Adaptin_N PF01602.20 EEQ30525.1 - 4.7e-115 385.1 0.4 6.4e-115 384.7 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EEQ30525.1 - 2.1e-59 200.0 2.3 4.9e-59 198.8 2.3 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EEQ30525.1 - 3.1e-32 111.1 0.2 1.5e-31 108.9 0.0 2.3 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EEQ30525.1 - 1.2e-18 67.2 2.3 6.7e-12 45.6 0.0 4.8 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 EEQ30525.1 - 3.7e-09 36.8 12.7 0.0021 18.1 0.1 5.3 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EEQ30525.1 - 0.00056 19.9 7.0 0.45 10.9 0.3 6.0 6 0 0 6 6 6 1 HEAT repeat Alpha_adaptin_C PF02296.16 EEQ30525.1 - 0.0066 16.6 0.0 0.026 14.7 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain HEAT_PBS PF03130.16 EEQ30525.1 - 0.019 15.6 4.7 3.8 8.4 0.1 4.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat DUF5010 PF16402.5 EEQ30525.1 - 0.17 10.7 0.0 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT_EZ PF13513.6 EEQ30525.1 - 0.46 11.0 4.9 0.17 12.4 0.5 2.7 3 0 0 3 3 3 0 HEAT-like repeat Phosducin PF02114.16 EEQ30526.1 - 1.2e-14 53.9 0.0 1.4e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Phosducin Exog_C PF18026.1 EEQ30526.1 - 0.34 11.0 4.4 9.5 6.4 1.7 2.4 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain bZIP_1 PF00170.21 EEQ30527.1 - 1.1e-05 25.4 13.2 1.8e-05 24.8 13.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 EEQ30527.1 - 4.6e-05 23.3 6.6 6.8e-05 22.7 6.6 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 EEQ30527.1 - 0.0061 14.5 0.8 0.0076 14.2 0.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.17 EEQ30527.1 - 0.022 15.2 11.0 0.035 14.6 11.0 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor CCDC106 PF15794.5 EEQ30527.1 - 0.03 14.0 7.2 0.021 14.6 4.0 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 GAS PF13851.6 EEQ30527.1 - 0.034 13.5 6.7 0.05 13.0 6.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.12 EEQ30527.1 - 0.081 12.8 1.7 0.17 11.8 1.7 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF1043 PF06295.12 EEQ30527.1 - 0.13 12.3 1.3 0.24 11.4 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) TMF_TATA_bd PF12325.8 EEQ30527.1 - 0.13 12.5 4.7 0.24 11.6 4.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.15 EEQ30527.1 - 0.74 9.9 17.7 1.2 9.3 16.3 1.9 1 1 1 2 2 2 0 Basic region leucine zipper PAP1 PF08601.10 EEQ30527.1 - 0.82 9.3 13.5 0.59 9.8 0.1 2.3 2 0 0 2 2 2 0 Transcription factor PAP1 Pkinase PF00069.25 EEQ30528.1 - 4.7e-26 91.7 0.0 5.9e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30528.1 - 6.1e-14 51.9 0.0 7.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ30528.1 - 4e-09 35.7 0.0 6.3e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEQ30528.1 - 0.00019 21.5 0.0 0.0015 18.5 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family MFS_1 PF07690.16 EEQ30529.1 - 7.8e-23 81.0 62.7 4.8e-17 61.9 39.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3754 PF12576.8 EEQ30529.1 - 0.21 11.6 3.4 7.5 6.5 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) US10 PF17617.2 EEQ30529.1 - 0.28 11.3 2.4 0.65 10.1 2.4 1.6 1 0 0 1 1 1 0 Viral unique short region 10 Kelch_5 PF13854.6 EEQ30530.1 - 2.7e-30 103.8 4.1 2.3e-08 33.9 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 EEQ30530.1 - 7e-28 96.3 13.1 1.4e-07 31.6 0.6 6.2 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EEQ30530.1 - 1e-27 95.4 2.0 3.1e-12 45.9 0.2 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EEQ30530.1 - 1.1e-26 92.6 11.5 9.9e-08 31.9 1.5 5.6 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EEQ30530.1 - 1.2e-23 82.5 5.5 4.4e-11 42.7 0.7 5.5 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EEQ30530.1 - 1.5e-22 78.6 5.1 3.8e-08 33.0 0.4 5.6 5 0 0 5 5 5 4 Kelch motif TPR_MLP1_2 PF07926.12 EEQ30530.1 - 0.0098 16.0 11.1 0.0098 16.0 11.1 8.8 6 2 5 11 11 11 2 TPR/MLP1/MLP2-like protein SID-1_RNA_chan PF13965.6 EEQ30530.1 - 4 5.7 5.1 13 4.1 5.1 1.8 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4396 PF14342.6 EEQ30531.1 - 1.2e-44 152.1 5.5 1.6e-44 151.7 5.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Raptor_N PF14538.6 EEQ30532.1 - 2.4e-65 218.9 0.0 4.9e-65 218.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EEQ30532.1 - 9.5e-06 26.3 2.4 0.39 11.7 0.1 5.3 4 0 0 4 4 4 1 WD domain, G-beta repeat HEAT PF02985.22 EEQ30532.1 - 0.0017 18.4 0.7 0.54 10.7 0.0 3.3 2 0 0 2 2 2 1 HEAT repeat Peptidase_C14 PF00656.22 EEQ30532.1 - 0.0026 17.8 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain HEAT_2 PF13646.6 EEQ30532.1 - 0.0061 16.9 0.0 0.021 15.2 0.0 1.9 1 0 0 1 1 1 1 HEAT repeats BBS2_Mid PF14783.6 EEQ30532.1 - 0.032 14.3 1.6 0.99 9.5 0.1 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.9 EEQ30532.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain US10 PF17617.2 EEQ30534.1 - 0.004 17.2 0.0 0.0048 17.0 0.0 1.1 1 0 0 1 1 1 1 Viral unique short region 10 zf-RING_2 PF13639.6 EEQ30535.1 - 4.6e-13 49.3 5.4 7.3e-13 48.6 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EEQ30535.1 - 3.8e-09 36.1 2.5 3.8e-09 36.1 2.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EEQ30535.1 - 5.7e-09 35.7 4.8 9.5e-09 35.0 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ30535.1 - 1.1e-08 35.2 3.1 2.2e-08 34.3 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EEQ30535.1 - 1.9e-08 34.1 4.0 3e-08 33.4 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 EEQ30535.1 - 1.1e-07 31.8 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 EEQ30535.1 - 1.5e-07 31.3 3.1 2.3e-07 30.7 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EEQ30535.1 - 3.9e-06 26.6 3.1 5.7e-06 26.1 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ30535.1 - 6.7e-06 26.0 2.2 1.1e-05 25.4 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EEQ30535.1 - 0.00052 20.0 0.5 0.00096 19.2 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EEQ30535.1 - 0.0014 18.4 3.1 0.0024 17.7 3.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EEQ30535.1 - 0.023 14.9 2.5 0.051 13.7 2.5 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EEQ30535.1 - 0.066 12.9 3.1 0.12 12.0 3.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EEQ30535.1 - 0.071 13.3 2.9 0.17 12.1 2.9 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EEQ30535.1 - 0.37 10.9 4.3 0.74 10.0 4.3 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EEQ30535.1 - 0.47 10.3 3.2 0.82 9.5 3.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EEQ30535.1 - 0.62 10.0 3.1 1.1 9.2 3.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 EEQ30535.1 - 2 8.8 3.7 3.7 7.9 3.7 1.4 1 0 0 1 1 1 0 RING-like domain EI24 PF07264.11 EEQ30536.1 - 4.4e-12 46.6 4.1 7.1e-12 45.9 4.1 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LysM PF01476.20 EEQ30537.1 - 1.3e-06 28.4 0.0 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.19 EEQ30537.1 - 0.015 15.8 14.0 0.015 15.8 14.0 3.7 5 0 0 5 5 5 0 Chitin recognition protein FAD_binding_3 PF01494.19 EEQ30538.1 - 5.1e-11 42.4 0.0 1e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EEQ30538.1 - 7.2e-05 22.9 0.1 0.00018 21.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ30538.1 - 0.0005 19.4 0.1 0.01 15.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ30538.1 - 0.00067 19.3 1.5 0.0012 18.6 0.4 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EEQ30538.1 - 0.0029 16.5 0.4 0.0048 15.8 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EEQ30538.1 - 0.045 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 EEQ30538.1 - 0.048 12.5 0.1 0.074 11.8 0.1 1.2 1 0 0 1 1 1 0 MCRA family DUF1967 PF09269.11 EEQ30538.1 - 0.06 13.3 0.9 0.29 11.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) NAD_binding_9 PF13454.6 EEQ30538.1 - 0.073 13.1 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding FHA PF00498.26 EEQ30539.1 - 2.2e-16 59.9 0.0 4.3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EEQ30539.1 - 0.00022 21.5 0.0 0.00056 20.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain GrpE PF01025.19 EEQ30539.1 - 1.7 8.3 15.9 0.042 13.5 3.8 2.4 2 0 0 2 2 2 0 GrpE LPP PF04728.13 EEQ30539.1 - 3 8.3 6.0 0.56 10.6 1.1 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Sigma70_ner PF04546.13 EEQ30539.1 - 5.2 6.9 15.9 0.28 11.0 7.4 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Romo1 PF10247.9 EEQ30540.1 - 2.1e-21 76.0 11.7 3e-21 75.6 11.7 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 LapA_dom PF06305.11 EEQ30540.1 - 3.7 7.4 3.9 20 5.1 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Iron_permease PF04120.12 EEQ30542.1 - 1.2e-40 138.2 5.4 4.9e-19 68.4 0.0 4.2 4 0 0 4 4 4 4 Low affinity iron permease DUF2839 PF10999.8 EEQ30542.1 - 2 8.9 5.7 3.8 7.9 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) LRR_8 PF13855.6 EEQ30543.1 - 1.6e-09 37.3 3.7 3.7e-09 36.2 1.4 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EEQ30543.1 - 2.7e-06 27.6 0.8 9.9e-06 25.8 0.3 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) DUF4451 PF14616.6 EEQ30543.1 - 0.067 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Ribosomal_S14 PF00253.21 EEQ30545.1 - 4.2e-20 71.3 1.5 1.5e-19 69.5 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e DASH_Spc19 PF08287.11 EEQ30546.1 - 9e-52 175.1 0.3 1.2e-51 174.7 0.3 1.2 1 0 0 1 1 1 1 Spc19 LPD30 PF18850.1 EEQ30546.1 - 0.094 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 WBS28 PF15164.6 EEQ30546.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue DUF4931 PF16285.5 EEQ30546.1 - 0.16 11.2 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) Rsm22 PF09243.10 EEQ30547.1 - 1.5e-29 103.1 0.0 8.6e-29 100.7 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Nucleo_P87 PF07267.11 EEQ30547.1 - 3.2 6.5 5.2 5.8 5.6 5.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BNR_3 PF13859.6 EEQ30548.1 - 9.2e-10 38.3 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR_2 PF13088.6 EEQ30548.1 - 4.8e-09 35.9 0.0 1e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 BNR repeat-like domain Rogdi_lz PF10259.9 EEQ30549.1 - 3.3e-83 279.2 0.0 3.8e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein HSP70 PF00012.20 EEQ30550.1 - 2.7e-73 247.1 1.7 2.7e-73 247.1 1.7 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ30550.1 - 6.1e-12 45.0 1.5 9.5e-12 44.4 1.5 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 EEQ30550.1 - 0.0019 18.0 0.2 0.003 17.3 0.2 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Cwf_Cwc_15 PF04889.12 EEQ30550.1 - 0.056 13.2 2.9 0.11 12.2 2.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PI3K_1B_p101 PF10486.9 EEQ30550.1 - 0.073 10.8 0.2 0.13 10.0 0.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CENP-B_dimeris PF09026.10 EEQ30550.1 - 0.44 11.0 5.5 0.95 9.9 5.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EEQ30550.1 - 2.2 7.5 4.8 3.6 6.8 4.8 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 EEQ30550.1 - 7.5 6.2 7.0 0.59 9.8 0.9 2.2 2 1 1 3 3 3 0 FAM176 family Phtf-FEM1B_bdg PF12129.8 EEQ30551.1 - 0.018 14.9 2.3 0.036 13.9 2.3 1.5 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor SLC3A2_N PF16028.5 EEQ30551.1 - 0.027 14.0 3.2 0.053 13.1 1.2 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus MpPF26 PF07666.11 EEQ30551.1 - 0.46 10.6 6.0 0.19 11.9 2.3 2.3 2 1 0 2 2 2 0 M penetrans paralogue family 26 p450 PF00067.22 EEQ30552.1 - 1.1e-19 70.5 0.0 1.4e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4116 PF13475.6 EEQ30552.1 - 0.12 12.1 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) E2F_CC-MB PF16421.5 EEQ30553.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain DUF4267 PF14087.6 EEQ30555.1 - 1.1e-24 86.6 5.1 1.3e-24 86.4 5.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Disaggr_repeat PF06848.11 EEQ30555.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Disaggregatase related repeat MFS_1 PF07690.16 EEQ30556.1 - 2.1e-38 132.2 55.9 3.3e-38 131.5 53.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ30556.1 - 3.3e-16 59.2 10.8 3.3e-16 59.2 10.8 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EEQ30556.1 - 1.9e-12 46.4 14.7 1.9e-12 46.4 14.7 1.6 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HNH_2 PF13391.6 EEQ30557.1 - 0.0078 16.3 0.5 0.018 15.1 0.5 1.6 1 0 0 1 1 1 1 HNH endonuclease Rpp20 PF12328.8 EEQ30558.1 - 1e-45 155.0 3.5 1.7e-45 154.4 3.5 1.3 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EEQ30558.1 - 2.4e-13 49.7 0.2 4.7e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 Alba KH_6 PF15985.5 EEQ30560.1 - 9.6e-16 57.9 0.1 2.1e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 KH domain PhzC-PhzF PF02567.16 EEQ30561.1 - 0.00056 19.5 0.2 0.012 15.1 0.1 2.1 2 0 0 2 2 2 1 Phenazine biosynthesis-like protein DUF305 PF03713.13 EEQ30561.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF305) Glyco_transf_24 PF18404.1 EEQ30563.1 - 1.9e-148 493.1 1.0 3.1e-148 492.4 1.0 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EEQ30563.1 - 4.3e-69 233.3 0.0 1.7e-66 224.7 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EEQ30563.1 - 2.3e-49 167.9 1.6 3.4e-49 167.3 0.2 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EEQ30563.1 - 3.5e-47 161.1 0.4 3.5e-47 161.1 0.4 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EEQ30563.1 - 2.5e-43 147.2 0.9 9e-43 145.5 0.2 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EEQ30563.1 - 4.5e-42 142.6 0.0 9.8e-42 141.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 EEQ30563.1 - 0.00088 18.9 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1416 PF07210.12 EEQ30563.1 - 0.079 12.9 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) Amidohydro_1 PF01979.20 EEQ30564.1 - 8.9e-25 87.7 0.0 1.1e-23 84.2 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EEQ30564.1 - 3.2e-11 43.4 0.0 4.7e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_26 PF02156.15 EEQ30564.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 5-nucleotidase PF06189.12 EEQ30564.1 - 0.28 10.1 0.0 0.48 9.3 0.0 1.3 1 0 0 1 1 1 0 5'-nucleotidase Vma12 PF11712.8 EEQ30565.1 - 7e-41 139.6 0.0 9.8e-41 139.1 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase MARVEL PF01284.23 EEQ30565.1 - 0.15 12.1 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Membrane-associating domain Prefoldin PF02996.17 EEQ30566.1 - 8.3e-30 103.2 0.2 1.4e-29 102.4 0.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EEQ30566.1 - 0.0085 16.0 0.5 0.071 13.1 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit End3 PF12761.7 EEQ30566.1 - 0.036 14.3 0.3 0.24 11.6 0.1 2.1 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 FlaC_arch PF05377.11 EEQ30566.1 - 0.045 14.2 0.3 1.4 9.3 0.1 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) LMP PF04778.12 EEQ30566.1 - 0.076 12.9 0.1 11 5.8 0.0 2.1 2 0 0 2 2 2 0 LMP repeated region DMPK_coil PF08826.10 EEQ30566.1 - 0.081 13.0 2.2 2.6 8.2 0.4 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Glyco_transf_28 PF03033.20 EEQ30567.1 - 5.7e-29 100.9 0.0 1.5e-28 99.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EEQ30567.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Prenylcys_lyase PF07156.14 EEQ30568.1 - 2.6e-96 322.9 0.0 3.5e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 EEQ30568.1 - 3.4e-14 53.0 0.0 5.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EEQ30568.1 - 4.2e-11 42.9 0.0 1.2e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ30568.1 - 2.4e-07 30.7 0.1 0.0064 16.1 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ30568.1 - 0.005 16.1 0.1 0.032 13.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ30568.1 - 0.0073 16.3 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EEQ30568.1 - 0.036 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PDCD2_C PF04194.13 EEQ30569.1 - 1e-43 149.4 0.2 9.6e-43 146.3 0.0 2.3 2 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain CSN8_PSD8_EIF3K PF10075.9 EEQ30570.1 - 2.9e-45 153.8 0.0 4e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Folliculin PF11704.8 EEQ30571.1 - 4.4e-49 166.9 0.0 6.9e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport CLP1_P PF16575.5 EEQ30572.1 - 4.4e-26 91.8 0.0 9.7e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 EEQ30572.1 - 0.047 13.8 0.5 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EEQ30572.1 - 0.098 13.2 0.1 0.41 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_polI_A34 PF08208.11 EEQ30573.1 - 2e-40 139.1 34.5 2e-40 139.1 34.5 3.3 2 2 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 PROL5-SMR PF15621.6 EEQ30573.1 - 6.6 7.3 9.1 1.8 9.2 3.9 2.4 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family SHMT PF00464.19 EEQ30574.1 - 3.2e-206 684.6 0.0 3.7e-206 684.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EEQ30574.1 - 1e-05 24.9 0.0 3.4e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ30574.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EEQ30574.1 - 0.13 10.8 0.0 0.24 9.9 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3040 PF11239.8 EEQ30574.1 - 0.16 12.3 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Med9 PF07544.13 EEQ30575.1 - 2.8e-15 56.2 0.7 4.4e-15 55.5 0.7 1.5 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 EEQ30575.1 - 0.0062 16.8 0.7 0.0062 16.8 0.7 2.1 2 0 0 2 2 2 1 Subunit 21 of Mediator complex SlyX PF04102.12 EEQ30575.1 - 0.026 15.1 0.7 0.063 13.9 0.7 1.7 1 0 0 1 1 1 0 SlyX Spc29 PF17082.5 EEQ30575.1 - 0.028 14.3 0.1 0.042 13.7 0.1 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 CLZ PF16526.5 EEQ30575.1 - 0.043 14.2 0.4 0.077 13.4 0.2 1.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels XhlA PF10779.9 EEQ30575.1 - 0.066 13.4 0.9 0.094 12.9 0.9 1.2 1 0 0 1 1 1 0 Haemolysin XhlA Fib_alpha PF08702.10 EEQ30575.1 - 0.066 13.4 0.4 0.094 12.9 0.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 EEQ30575.1 - 0.093 12.5 0.9 0.14 12.0 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator iPGM_N PF06415.13 EEQ30576.1 - 7.6e-78 260.9 0.0 1e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EEQ30576.1 - 7.2e-71 238.4 0.0 8.3e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EEQ30576.1 - 0.00035 20.1 0.0 0.012 15.0 0.0 2.5 2 1 1 3 3 3 1 Sulfatase Alk_phosphatase PF00245.20 EEQ30576.1 - 0.0083 15.1 0.1 0.047 12.6 0.0 1.9 2 0 0 2 2 2 1 Alkaline phosphatase Prefoldin_2 PF01920.20 EEQ30577.1 - 3.7e-21 75.1 17.1 4.9e-21 74.7 17.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EEQ30577.1 - 8e-06 25.8 7.3 1.1e-05 25.4 7.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EEQ30577.1 - 0.002 18.0 0.9 0.002 18.0 0.9 2.5 2 1 0 2 2 2 1 Prefoldin subunit DUF5082 PF16888.5 EEQ30577.1 - 0.0039 17.5 12.4 0.0066 16.7 12.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) Spc7 PF08317.11 EEQ30577.1 - 0.0053 15.7 14.4 0.0074 15.2 14.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc24 PF08286.11 EEQ30577.1 - 0.01 16.0 16.5 0.039 14.2 6.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Swi5 PF07061.11 EEQ30577.1 - 0.017 15.2 10.5 0.55 10.3 5.9 2.3 2 0 0 2 2 2 0 Swi5 NPV_P10 PF05531.12 EEQ30577.1 - 0.017 15.6 8.7 0.61 10.6 2.7 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 EEQ30577.1 - 0.019 15.1 16.7 0.098 12.8 7.7 2.3 2 0 0 2 2 2 0 Tropomyosin like ABC_tran_CTD PF16326.5 EEQ30577.1 - 0.025 14.8 23.2 0.27 11.5 5.6 3.3 2 2 1 3 3 3 0 ABC transporter C-terminal domain Osmo_CC PF08946.10 EEQ30577.1 - 0.036 14.3 5.0 0.036 14.3 5.0 2.7 2 2 0 2 2 2 0 Osmosensory transporter coiled coil Siah-Interact_N PF09032.11 EEQ30577.1 - 0.04 14.2 10.7 0.71 10.2 3.9 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal YabA PF06156.13 EEQ30577.1 - 0.046 14.3 9.8 1.4 9.6 0.4 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Spore_YpjB PF09577.10 EEQ30577.1 - 0.048 13.5 4.3 0.062 13.1 4.3 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF4349 PF14257.6 EEQ30577.1 - 0.051 13.0 11.4 0.053 13.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) SOGA PF11365.8 EEQ30577.1 - 0.056 14.6 5.5 4.6 8.4 0.1 2.1 2 0 0 2 2 2 0 Protein SOGA TMF_TATA_bd PF12325.8 EEQ30577.1 - 0.068 13.4 13.4 0.4 10.9 6.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3727 PF12527.8 EEQ30577.1 - 0.11 12.7 4.2 0.51 10.6 1.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3727) DivIC PF04977.15 EEQ30577.1 - 0.12 12.1 20.5 0.79 9.5 1.1 3.1 2 1 1 3 3 3 0 Septum formation initiator GrpE PF01025.19 EEQ30577.1 - 0.2 11.3 14.4 1.1 8.9 1.2 2.1 2 0 0 2 2 2 0 GrpE Chibby PF14645.6 EEQ30577.1 - 0.24 11.8 0.3 0.24 11.8 0.3 2.7 1 1 2 3 3 3 0 Chibby family DUF1664 PF07889.12 EEQ30577.1 - 0.25 11.4 11.2 1.9 8.6 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1779 PF08680.10 EEQ30577.1 - 0.25 11.5 7.0 0.28 11.3 7.0 1.0 1 0 0 1 1 1 0 TATA-box binding PHM7_cyt PF14703.6 EEQ30577.1 - 0.27 11.4 8.4 0.52 10.5 8.4 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter TPR_MLP1_2 PF07926.12 EEQ30577.1 - 0.3 11.2 16.4 0.41 10.7 8.7 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EEQ30577.1 - 0.33 10.3 11.1 0.53 9.6 11.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MtrG PF04210.13 EEQ30577.1 - 0.36 10.7 6.2 0.23 11.3 1.3 2.5 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Uso1_p115_C PF04871.13 EEQ30577.1 - 0.36 11.2 15.9 0.49 10.8 8.6 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region End3 PF12761.7 EEQ30577.1 - 0.4 10.8 11.1 0.51 10.5 11.1 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TolA_bind_tri PF16331.5 EEQ30577.1 - 0.46 10.6 13.9 1.1 9.4 6.1 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation APG6_N PF17675.1 EEQ30577.1 - 0.51 10.9 22.5 2.8 8.5 13.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4200 PF13863.6 EEQ30577.1 - 0.56 10.6 18.1 3 8.3 7.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Taxilin PF09728.9 EEQ30577.1 - 0.59 9.3 19.0 7.3 5.7 19.0 2.0 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DASH_Spc19 PF08287.11 EEQ30577.1 - 0.65 9.9 13.0 0.42 10.5 1.0 2.1 1 1 1 2 2 2 0 Spc19 FliJ PF02050.16 EEQ30577.1 - 0.66 10.2 16.6 1.5 9.0 0.5 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Apt1 PF10351.9 EEQ30577.1 - 0.69 8.7 7.6 0.89 8.3 7.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4164 PF13747.6 EEQ30577.1 - 0.7 10.2 11.6 0.55 10.5 5.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Laminin_II PF06009.12 EEQ30577.1 - 0.74 9.8 10.4 3.3 7.7 0.4 2.0 1 1 0 2 2 2 0 Laminin Domain II Rx_N PF18052.1 EEQ30577.1 - 0.77 10.1 11.6 0.51 10.6 3.6 2.3 2 1 0 2 2 2 0 Rx N-terminal domain betaPIX_CC PF16523.5 EEQ30577.1 - 0.84 9.5 9.2 0.2 11.5 3.8 2.3 2 1 0 2 2 2 0 betaPIX coiled coil SlyX PF04102.12 EEQ30577.1 - 0.95 10.1 13.7 2.1 9.1 0.3 2.9 2 1 0 2 2 2 0 SlyX ERp29 PF07749.12 EEQ30577.1 - 1 10.3 8.6 3.4 8.6 8.6 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain FlaC_arch PF05377.11 EEQ30577.1 - 1.1 9.7 13.3 1.3 9.5 1.6 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 EEQ30577.1 - 1.1 9.3 9.5 2.8 8.0 2.7 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Rootletin PF15035.6 EEQ30577.1 - 1.2 9.2 12.4 0.34 10.9 6.3 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4337 PF14235.6 EEQ30577.1 - 1.4 9.0 10.8 3.1 7.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) CENP-H PF05837.12 EEQ30577.1 - 1.4 9.3 13.5 3.6 8.0 0.9 2.2 1 1 0 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 EEQ30577.1 - 1.5 9.3 19.0 2.3 8.7 9.9 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DHR10 PF18595.1 EEQ30577.1 - 1.6 8.8 19.1 3.3 7.8 8.9 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF724 PF05266.14 EEQ30577.1 - 1.6 8.5 13.4 0.44 10.3 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Muted PF14942.6 EEQ30577.1 - 1.8 8.9 16.2 2.2 8.6 1.9 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Occludin_ELL PF07303.13 EEQ30577.1 - 1.8 9.4 8.7 17 6.2 8.8 2.1 1 1 0 1 1 1 0 Occludin homology domain TMF_DNA_bd PF12329.8 EEQ30577.1 - 1.8 8.6 16.9 4.6 7.3 1.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding KELK PF15796.5 EEQ30577.1 - 2.5 8.6 16.0 2.8 8.5 0.9 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3450 PF11932.8 EEQ30577.1 - 2.5 7.3 15.1 1.5 8.1 8.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Peptidase_S49_N PF08496.10 EEQ30577.1 - 2.9 7.9 10.3 4.2 7.4 10.1 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal CENP-Q PF13094.6 EEQ30577.1 - 3 8.0 13.4 7.3 6.8 13.4 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DASH_Spc34 PF08657.10 EEQ30577.1 - 3.1 7.5 10.4 3.9 7.2 10.4 1.3 1 1 0 1 1 1 0 DASH complex subunit Spc34 Csm1_N PF18504.1 EEQ30577.1 - 3.7 7.9 18.5 2.5 8.5 0.8 3.7 2 2 1 3 3 3 0 Csm1 N-terminal domain BRE1 PF08647.11 EEQ30577.1 - 4.6 7.4 18.4 1.2 9.2 2.6 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Flagellin_N PF00669.20 EEQ30577.1 - 5.8 7.0 8.6 1.3 9.1 4.0 1.9 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Fib_alpha PF08702.10 EEQ30577.1 - 6.1 7.0 14.7 3.8e+02 1.2 14.7 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 EEQ30577.1 - 6.1 7.1 9.1 0.27 11.5 1.2 2.3 2 1 0 2 2 2 0 Haemolysin XhlA CCDC-167 PF15188.6 EEQ30577.1 - 6.2 7.2 10.5 16 5.9 4.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ERM PF00769.19 EEQ30577.1 - 6.8 6.4 19.9 17 5.2 19.9 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TMPIT PF07851.13 EEQ30577.1 - 9.7 5.3 11.1 22 4.2 11.2 1.5 1 1 0 1 1 1 0 TMPIT-like protein AAA PF00004.29 EEQ30578.1 - 1.4e-42 145.3 0.0 2.3e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EEQ30578.1 - 2.6e-27 94.6 0.2 8.5e-27 92.9 0.2 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EEQ30578.1 - 2.2e-23 82.1 1.6 4.8e-23 81.0 1.6 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EEQ30578.1 - 7e-06 25.8 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EEQ30578.1 - 9.9e-06 25.4 0.0 2.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EEQ30578.1 - 3.3e-05 24.1 0.0 0.00037 20.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EEQ30578.1 - 3.8e-05 24.1 0.0 0.00022 21.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EEQ30578.1 - 4.3e-05 23.5 0.0 0.00019 21.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EEQ30578.1 - 8.6e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EEQ30578.1 - 0.00013 22.3 0.0 0.0076 16.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EEQ30578.1 - 0.00017 20.9 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EEQ30578.1 - 0.00019 21.5 0.0 0.00048 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEQ30578.1 - 0.00025 21.6 0.0 0.0016 19.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EEQ30578.1 - 0.00068 18.9 0.0 0.0058 15.8 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EEQ30578.1 - 0.0021 18.3 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEQ30578.1 - 0.0027 18.1 0.0 0.01 16.2 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.6 EEQ30578.1 - 0.0039 17.0 0.1 0.011 15.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain ATPase PF06745.13 EEQ30578.1 - 0.0049 16.2 0.0 4.8 6.5 0.0 2.9 1 1 1 3 3 3 1 KaiC AAA_17 PF13207.6 EEQ30578.1 - 0.0073 16.7 0.0 0.035 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EEQ30578.1 - 0.015 14.8 0.0 0.081 12.4 0.0 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EEQ30578.1 - 0.016 14.8 0.2 0.71 9.4 0.1 2.6 2 1 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 EEQ30578.1 - 0.039 13.3 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 EEQ30578.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Torsin NACHT PF05729.12 EEQ30578.1 - 0.065 13.1 0.0 0.68 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 EEQ30578.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 EEQ30578.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EEQ30578.1 - 0.15 11.7 0.0 0.57 9.9 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain CPT PF07931.12 EEQ30578.1 - 0.17 11.7 0.0 0.5 10.2 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ATPase_2 PF01637.18 EEQ30578.1 - 0.18 11.7 0.1 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Cnn_1N PF07989.11 EEQ30579.1 - 3.8e-23 81.4 6.2 3.8e-23 81.4 6.2 14.2 6 2 7 14 14 14 3 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 EEQ30579.1 - 1.3e-10 41.7 3.6 1.3e-10 41.7 3.6 5.6 6 1 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_DNA_bd PF12329.8 EEQ30579.1 - 4.9e-09 36.0 17.3 4.9e-09 36.0 17.3 16.0 7 5 7 14 14 14 3 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.8 EEQ30579.1 - 0.007 16.4 3.9 0.007 16.4 3.9 11.1 4 3 7 13 13 13 2 Protein of unknown function (DUF2730) DUF4200 PF13863.6 EEQ30579.1 - 0.011 16.1 18.4 0.011 16.1 18.4 11.9 3 2 6 11 11 11 0 Domain of unknown function (DUF4200) SGT1 PF07093.11 EEQ30580.1 - 6.3e-92 308.9 12.3 7.2e-81 272.4 0.0 2.0 1 1 1 2 2 2 2 SGT1 protein DUF1007 PF06226.13 EEQ30580.1 - 0.45 10.5 1.6 0.57 10.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1007) AMP-binding PF00501.28 EEQ30581.1 - 3.7e-37 127.9 0.0 4.9e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ30581.1 - 0.0006 20.7 0.0 0.0013 19.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EEQ30582.1 - 2.7e-38 131.7 0.0 3.8e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMMECR1 PF01871.17 EEQ30584.1 - 8.3e-40 136.1 0.0 2e-39 134.9 0.0 1.6 2 0 0 2 2 2 1 AMMECR1 Mucin PF01456.17 EEQ30584.1 - 0.013 15.5 2.8 0.02 14.9 2.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Apt1 PF10351.9 EEQ30584.1 - 0.085 11.7 4.6 0.095 11.5 4.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 EEQ30584.1 - 3.4 5.3 6.4 4.4 5.0 6.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 EEQ30584.1 - 6.9 5.1 6.7 9.2 4.7 6.7 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 EEQ30586.1 - 7.1e-71 238.6 0.0 9e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30586.1 - 3e-28 98.8 0.0 4e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ30586.1 - 2.4e-07 30.4 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ30586.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEQ30586.1 - 0.00052 20.0 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ30586.1 - 0.00062 19.2 0.1 0.001 18.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1744 PF08490.12 EEQ30587.1 - 3.7e-150 500.0 0.2 5.5e-150 499.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EEQ30587.1 - 1.3e-82 277.6 0.9 3.5e-82 276.3 0.9 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EEQ30587.1 - 2.6e-16 59.4 0.0 3.3e-13 49.2 0.0 3.6 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EEQ30587.1 - 7.8e-10 38.8 0.4 2.6e-09 37.1 0.4 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EEQ30587.1 - 2.5e-05 24.3 0.1 9.1e-05 22.5 0.1 2.0 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.8 EEQ30588.1 - 2.4e-31 107.5 0.4 4.6e-31 106.6 0.1 1.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3767) Anophelin PF10731.9 EEQ30589.1 - 8.7 6.3 8.6 0.26 11.2 1.1 2.3 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito Nop PF01798.18 EEQ30590.1 - 1.6e-86 289.5 0.0 1.6e-86 289.5 0.0 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EEQ30590.1 - 3e-18 65.9 0.1 3e-18 65.9 0.1 2.8 3 1 0 3 3 3 1 NOP5NT (NUC127) domain TCP PF03634.13 EEQ30590.1 - 0.027 15.0 13.2 0.05 14.2 13.2 1.5 1 0 0 1 1 1 0 TCP family transcription factor RP-C_C PF11800.8 EEQ30590.1 - 0.14 12.3 11.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region GAGA_bind PF06217.12 EEQ30590.1 - 0.56 10.4 13.7 1.1 9.5 13.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.11 EEQ30590.1 - 5.2 7.1 39.4 9.2 6.3 39.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CobT PF06213.12 EEQ30590.1 - 5.4 6.3 21.3 7.5 5.8 20.0 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 EEQ30590.1 - 7.5 6.3 21.7 13 5.6 21.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EEQ30590.1 - 7.5 6.6 8.0 14 5.8 8.0 1.4 1 0 0 1 1 1 0 DDHD domain Cpn60_TCP1 PF00118.24 EEQ30591.1 - 6.2e-161 536.3 1.2 7e-161 536.2 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.18 EEQ30592.1 - 1.3e-64 217.1 0.0 1.8e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EEQ30592.1 - 1e-15 57.0 0.3 2e-15 56.1 0.3 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain RRM_1 PF00076.22 EEQ30593.1 - 4.9e-15 55.1 0.0 8.6e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup54 PF13874.6 EEQ30593.1 - 0.0012 18.9 0.4 0.0028 17.8 0.4 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 AA_permease_2 PF13520.6 EEQ30594.1 - 1.8e-47 162.1 37.9 3.8e-34 118.2 16.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 EEQ30594.1 - 6.1e-11 41.6 33.1 3.6e-07 29.2 13.4 2.1 1 1 1 2 2 2 2 Amino acid permease DUF4690 PF15756.5 EEQ30594.1 - 0.27 11.9 1.6 2.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Small Novel Rich in Cartilage DUF2721 PF11026.8 EEQ30594.1 - 0.99 9.3 0.0 0.99 9.3 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2721) YrhK PF14145.6 EEQ30594.1 - 7.4 6.5 10.8 0.39 10.6 0.9 3.6 3 0 0 3 3 3 0 YrhK-like protein Sec23_trunk PF04811.15 EEQ30595.1 - 2.9e-40 138.4 0.0 3.3e-39 134.9 0.0 2.1 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EEQ30595.1 - 1.5e-22 79.3 0.0 3.1e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EEQ30595.1 - 1.1e-17 64.5 0.0 8.7e-17 61.7 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EEQ30595.1 - 5.3e-15 55.2 5.8 1.1e-14 54.2 5.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EEQ30595.1 - 5e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Fe-ADH PF00465.19 EEQ30595.1 - 0.21 10.4 0.2 0.47 9.2 0.2 1.5 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Bys1 PF04681.12 EEQ30596.1 - 1.1e-06 28.7 0.3 1.4e-06 28.4 0.3 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein ABC_tran PF00005.27 EEQ30597.1 - 2e-49 167.6 0.1 1.6e-25 90.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EEQ30597.1 - 2.6e-47 161.0 34.9 1.3e-26 93.3 13.9 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 EEQ30597.1 - 1.9e-12 47.6 0.8 0.0026 17.6 0.1 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ30597.1 - 8.6e-09 35.1 0.5 0.024 14.1 0.1 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EEQ30597.1 - 9.1e-08 32.2 1.8 0.0058 16.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EEQ30597.1 - 1.6e-07 32.0 1.2 0.003 18.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEQ30597.1 - 1.2e-06 29.0 0.1 0.08 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EEQ30597.1 - 1e-05 25.2 3.0 0.09 12.5 0.9 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EEQ30597.1 - 3.8e-05 23.7 1.3 0.039 13.9 0.0 2.4 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 EEQ30597.1 - 9.1e-05 22.5 0.2 0.0051 16.7 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EEQ30597.1 - 0.00023 21.0 0.2 0.41 10.3 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EEQ30597.1 - 0.00025 21.3 0.6 0.61 10.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EEQ30597.1 - 0.0009 19.0 0.7 6.4 6.4 0.3 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.6 EEQ30597.1 - 0.0009 18.9 0.4 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EEQ30597.1 - 0.00092 19.0 0.7 0.077 12.7 0.2 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EEQ30597.1 - 0.001 19.5 0.6 2 8.9 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEQ30597.1 - 0.003 17.6 0.1 3.2 7.7 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 EEQ30597.1 - 0.0045 16.3 0.2 2.2 7.5 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain T2SSE PF00437.20 EEQ30597.1 - 0.0047 16.0 0.5 1.4 7.9 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.6 EEQ30597.1 - 0.0051 17.1 3.0 1.7 8.9 1.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EEQ30597.1 - 0.0061 16.9 1.0 0.88 9.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EEQ30597.1 - 0.0062 16.2 3.8 0.28 10.7 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EEQ30597.1 - 0.027 14.8 0.3 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 EEQ30597.1 - 0.028 15.0 0.2 2 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EEQ30597.1 - 0.036 14.3 1.2 4.2 7.6 0.2 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 EEQ30597.1 - 0.052 13.3 0.4 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2125 PF09898.9 EEQ30597.1 - 0.057 13.1 0.1 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2125) AAA_11 PF13086.6 EEQ30597.1 - 0.1 12.4 0.2 0.83 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EEQ30597.1 - 0.1 12.5 1.1 7.3 6.5 0.3 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 EEQ30597.1 - 0.14 11.8 1.1 8.1 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 EEQ30597.1 - 0.15 11.5 2.2 6.3 6.2 0.4 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein PDR_assoc PF08370.11 EEQ30597.1 - 0.16 11.7 0.5 0.57 10.0 0.5 1.9 1 0 0 1 1 1 0 Plant PDR ABC transporter associated AAA_17 PF13207.6 EEQ30597.1 - 0.18 12.2 1.2 11 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EEQ30597.1 - 0.22 11.3 0.6 23 4.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_35 PF14516.6 EEQ30597.1 - 0.27 10.0 0.3 5.1 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.23 EEQ30597.1 - 0.3 11.2 4.3 2.7 8.1 1.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 EEQ30597.1 - 0.31 10.8 1.3 14 5.3 0.4 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 EEQ30597.1 - 0.45 10.4 1.6 28 4.5 0.0 2.7 3 0 0 3 3 2 0 NTPase AAA_33 PF13671.6 EEQ30597.1 - 0.55 10.4 1.6 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EEQ30597.1 - 2.2 7.5 4.7 8 5.7 0.3 2.5 3 0 0 3 3 2 0 Zeta toxin Fungal_trans_2 PF11951.8 EEQ30599.1 - 6.5e-69 232.6 0.0 8.6e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ30599.1 - 1.4e-09 37.9 10.0 2.6e-09 37.1 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 EEQ30599.1 - 1.8 8.7 10.0 6.9 6.9 10.0 2.1 1 0 0 1 1 1 0 AT hook motif ESR1_C PF12743.7 EEQ30601.1 - 0.0071 16.1 0.3 0.013 15.3 0.3 1.4 1 0 0 1 1 1 1 Oestrogen-type nuclear receptor final C-terminal DUF2434 PF10361.9 EEQ30602.1 - 1.5e-123 411.5 8.6 1.9e-123 411.2 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Gti1_Pac2 PF09729.9 EEQ30603.1 - 7.4e-46 156.5 1.4 1.5e-38 132.7 0.1 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family tRNA-synt_2 PF00152.20 EEQ30604.1 - 2.9e-58 197.4 0.0 2.6e-57 194.3 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ30604.1 - 1.6e-07 31.2 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SLBB PF10531.9 EEQ30605.1 - 0.098 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 SLBB domain Lactamase_B_6 PF16661.5 EEQ30606.1 - 2.9e-61 206.3 0.0 5.8e-61 205.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EEQ30606.1 - 5.2e-46 156.9 0.1 5.2e-46 156.9 0.1 2.7 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EEQ30606.1 - 1.9e-16 60.3 0.0 7e-16 58.5 0.0 2.0 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EEQ30606.1 - 1e-12 47.8 0.0 2.3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EEQ30606.1 - 0.081 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily CDT1_C PF16679.5 EEQ30607.1 - 2.4e-18 66.3 0.1 4.9e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Apolipoprotein PF01442.18 EEQ30608.1 - 0.0028 17.6 1.3 0.0032 17.4 1.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin PF05597.11 EEQ30608.1 - 0.0094 15.9 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) HEPN_SAV_6107 PF18726.1 EEQ30608.1 - 0.03 14.8 0.2 0.042 14.4 0.2 1.3 1 0 0 1 1 1 0 SAV_6107-like HEPN DUF1664 PF07889.12 EEQ30608.1 - 0.069 13.2 0.7 0.6 10.2 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 EEQ30608.1 - 0.086 13.5 5.4 0.1 13.2 2.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Pannexin_like PF12534.8 EEQ30608.1 - 0.54 9.3 4.5 0.7 8.9 4.5 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Frag1 PF10277.9 EEQ30609.1 - 4.4e-40 137.6 7.2 4.4e-40 137.6 7.2 2.4 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 EEQ30609.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.11 EEQ30610.1 - 3.6e-19 68.6 4.5 6.9e-18 64.5 1.7 3.1 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EEQ30610.1 - 2.3e-06 28.0 4.2 0.058 14.2 0.6 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 EEQ30610.1 - 0.0062 15.8 0.5 0.011 15.0 0.5 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EEQ30610.1 - 0.027 13.6 0.2 0.047 12.8 0.2 1.5 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference RF-1 PF00472.20 EEQ30611.1 - 4.4e-20 71.8 0.5 6e-20 71.3 0.5 1.1 1 0 0 1 1 1 1 RF-1 domain RRM_1 PF00076.22 EEQ30612.1 - 3.6e-09 36.3 0.0 8.1e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ30612.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.17 EEQ30613.1 - 4.3e-24 84.6 2.1 5.5e-24 84.2 2.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Swi6_N PF18530.1 EEQ30613.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.5 2 0 0 2 2 2 0 Swi6 N-terminal domain Pet191_N PF10203.9 EEQ30613.1 - 0.11 12.8 1.1 0.4 11.0 1.1 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.9 EEQ30614.1 - 1.5e-53 180.9 7.6 1.7e-53 180.7 7.6 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.12 EEQ30614.1 - 0.019 14.9 2.1 0.019 14.9 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF485 FXMRP1_C_core PF12235.8 EEQ30614.1 - 0.13 12.9 2.1 0.17 12.5 2.1 1.1 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal COG5 PF10392.9 EEQ30616.1 - 7.5e-38 129.7 1.5 3.5e-37 127.5 0.0 2.6 3 0 0 3 3 3 1 Golgi transport complex subunit 5 MutS_V PF00488.21 EEQ30620.1 - 3.3e-81 271.8 0.0 6.2e-81 270.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EEQ30620.1 - 3.9e-36 125.1 0.2 1e-35 123.7 0.2 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 EEQ30620.1 - 1.7e-22 80.2 0.1 6.4e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EEQ30620.1 - 9.6e-20 70.7 0.5 3.1e-19 69.1 0.5 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 EEQ30620.1 - 1.9e-16 60.3 0.0 1.6e-15 57.3 0.0 2.2 2 0 0 2 2 2 1 MutS domain I Gpi1 PF05024.15 EEQ30621.1 - 2.5e-76 256.0 9.5 4.3e-76 255.2 9.5 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DNA_pol_A_exo1 PF01612.20 EEQ30623.1 - 4.7e-41 140.4 0.4 7.4e-41 139.8 0.4 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EEQ30623.1 - 1.6e-31 108.8 2.6 1.9e-30 105.4 1.1 2.9 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EEQ30623.1 - 5.8e-11 42.2 0.6 1.4e-10 41.0 0.1 2.0 2 0 0 2 2 2 1 HRDC domain Dopey_N PF04118.14 EEQ30623.1 - 0.081 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Dopey, N-terminal RasGAP PF00616.19 EEQ30624.1 - 1.3e-56 191.7 0.3 5.4e-56 189.6 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EEQ30624.1 - 2.6e-31 108.6 5.6 2.6e-31 108.6 5.6 2.7 2 1 0 2 2 2 1 RasGAP C-terminus CRAL_TRIO PF00650.20 EEQ30625.1 - 9.1e-38 129.5 0.0 1.2e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ30625.1 - 1.4e-06 28.4 0.7 1.4e-06 28.4 0.7 2.4 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEQ30625.1 - 0.0014 18.8 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.12 EEQ30626.1 - 8.4e-20 71.4 12.5 1.9e-19 70.3 12.5 1.7 1 1 0 1 1 1 1 Kinetochore protein Mis14 like Grg1 PF11034.8 EEQ30628.1 - 0.21 11.8 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Glucose-repressible protein Grg1 Acetyltransf_1 PF00583.25 EEQ30629.1 - 3.7e-19 69.1 0.1 5.1e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ30629.1 - 9.6e-12 45.2 0.0 1.5e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ30629.1 - 1.2e-11 44.4 0.0 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EEQ30629.1 - 2e-11 43.9 0.0 2.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EEQ30629.1 - 9.8e-08 32.8 0.0 1.3e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EEQ30629.1 - 4.1e-07 29.8 0.0 1.5e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEQ30629.1 - 1.5e-05 25.1 0.2 4.5e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EEQ30629.1 - 0.00027 21.0 0.0 0.00061 19.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EEQ30629.1 - 0.0051 17.0 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EEQ30629.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase GNAT_acetyltran PF12746.7 EEQ30629.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 GNAT acetyltransferase LCAT PF02450.15 EEQ30630.1 - 1.8e-101 340.1 0.0 2.3e-101 339.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EEQ30630.1 - 0.0004 21.0 0.0 0.00083 20.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 EEQ30630.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) LIDHydrolase PF10230.9 EEQ30630.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase STT3 PF02516.14 EEQ30630.1 - 0.25 10.2 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit PAP2_3 PF14378.6 EEQ30631.1 - 5e-16 59.0 22.6 7.8e-09 35.5 1.8 3.1 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 EEQ30631.1 - 2.7e-05 23.9 1.7 2.7e-05 23.9 1.7 2.0 2 0 0 2 2 2 1 PAP2 superfamily Sugar_tr PF00083.24 EEQ30632.1 - 1.7e-32 112.8 23.3 5.4e-30 104.7 23.3 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ30632.1 - 1.8e-30 106.1 27.4 1.8e-30 106.1 27.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 EEQ30633.1 - 9.5e-22 77.6 0.0 3.5e-21 75.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30633.1 - 3.6e-07 29.7 0.0 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ30633.1 - 0.0023 16.8 0.2 0.0034 16.2 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EEQ30633.1 - 0.05 13.2 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EEQ30633.1 - 0.057 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1768 PF08719.11 EEQ30635.1 - 2.7e-56 190.3 0.0 3e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) TMEMspv1-c74-12 PF11044.8 EEQ30636.1 - 0.013 15.5 0.3 0.03 14.3 0.3 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Pilin_N PF07790.11 EEQ30636.1 - 0.019 15.9 1.8 0.036 15.0 1.8 1.5 1 1 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF1449 PF07290.11 EEQ30636.1 - 0.032 13.8 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) LapA_dom PF06305.11 EEQ30636.1 - 0.054 13.3 0.5 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ibs_toxin PF13956.6 EEQ30636.1 - 0.078 13.0 2.5 0.078 13.0 2.5 1.7 2 0 0 2 2 2 0 Toxin Ibs, type I toxin-antitoxin system DUF4492 PF14899.6 EEQ30636.1 - 0.24 11.3 2.7 0.12 12.3 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) DUF4307 PF14155.6 EEQ30636.1 - 0.31 10.9 3.7 11 5.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) Peptidase_M28 PF04389.17 EEQ30640.1 - 1.5e-32 112.9 0.1 2.4e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EEQ30640.1 - 0.00031 20.5 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EEQ30640.1 - 0.0093 15.4 0.0 0.044 13.2 0.0 2.1 2 0 0 2 2 2 1 Nicastrin Glyco_hydro81C PF17652.1 EEQ30641.1 - 1.8e-163 543.8 3.5 2.4e-163 543.4 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EEQ30641.1 - 1.9e-92 309.9 0.0 2.9e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain CsbD PF05532.12 EEQ30641.1 - 0.031 14.2 0.4 0.28 11.1 0.1 2.4 2 0 0 2 2 2 0 CsbD-like Utp14 PF04615.13 EEQ30642.1 - 3.4e-214 713.7 64.7 3.4e-214 713.7 64.7 2.3 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.9 EEQ30643.1 - 7.8e-12 45.0 0.2 1e-11 44.7 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HECT PF00632.25 EEQ30644.1 - 1e-76 258.4 0.0 2.1e-76 257.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EEQ30644.1 - 0.0037 16.9 0.6 0.015 15.0 0.6 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif RRM_1 PF00076.22 EEQ30645.1 - 6.2e-75 247.0 5.0 2.8e-22 78.3 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EEQ30645.1 - 3.5e-27 94.4 0.2 1.7e-26 92.2 0.2 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EEQ30645.1 - 2.6e-11 43.2 0.3 0.98 9.0 0.1 5.2 2 1 3 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ30645.1 - 1.8e-06 27.7 0.1 0.0056 16.5 0.0 3.5 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EEQ30645.1 - 1.8e-05 24.8 0.3 5 7.3 0.0 4.5 4 1 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EEQ30645.1 - 0.0028 17.6 0.2 28 4.8 0.0 4.7 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EEQ30645.1 - 0.01 15.9 0.6 3.9 7.6 0.0 3.6 3 0 0 3 3 3 0 Limkain b1 RRM_3 PF08777.11 EEQ30645.1 - 0.015 15.3 14.0 0.38 10.8 2.0 4.7 4 1 1 5 5 5 0 RNA binding motif IF2_N PF04760.15 EEQ30645.1 - 0.035 13.9 0.3 6 6.8 0.0 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region OB_RNB PF08206.11 EEQ30645.1 - 0.084 12.6 1.9 15 5.4 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.8 EEQ30645.1 - 0.53 10.8 8.6 2 9.0 0.7 3.3 3 0 0 3 3 3 0 Heat induced stress protein YflT Fe-ADH PF00465.19 EEQ30646.1 - 5.4e-70 236.0 2.4 7.1e-70 235.6 2.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EEQ30646.1 - 3e-21 76.3 0.5 4.5e-21 75.7 0.5 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EEQ30646.1 - 0.0015 17.7 0.1 0.77 8.9 0.1 2.3 2 0 0 2 2 2 2 3-dehydroquinate synthase Peripla_BP_6 PF13458.6 EEQ30646.1 - 0.0025 17.5 0.2 0.0045 16.7 0.1 1.5 2 0 0 2 2 2 1 Periplasmic binding protein PFK PF00365.20 EEQ30646.1 - 0.0041 16.5 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphofructokinase DAO PF01266.24 EEQ30647.1 - 1.9e-62 211.9 0.0 2.1e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ30647.1 - 3.7e-05 23.9 0.8 7.8e-05 22.8 0.8 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EEQ30647.1 - 7.2e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ30647.1 - 0.002 17.4 0.0 0.0093 15.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEQ30647.1 - 0.013 14.7 0.2 0.042 13.1 0.1 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 EEQ30647.1 - 0.015 14.6 0.2 0.029 13.6 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EEQ30647.1 - 0.029 14.9 0.4 0.058 13.9 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EEQ30647.1 - 0.032 13.5 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EEQ30647.1 - 0.046 13.7 0.2 0.088 12.8 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EEQ30647.1 - 0.061 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EEQ30647.1 - 0.07 13.0 0.4 0.12 12.3 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EEQ30647.1 - 0.2 11.3 0.2 0.31 10.7 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EEQ30647.1 - 0.21 10.8 0.2 0.57 9.4 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEQ30647.1 - 0.22 10.6 2.2 0.35 9.9 2.2 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EEQ30647.1 - 0.28 10.2 0.5 0.55 9.2 0.5 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Vps52 PF04129.12 EEQ30648.1 - 6.2e-119 398.0 0.5 8.4e-119 397.6 0.5 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EEQ30648.1 - 0.00036 19.1 1.1 0.00053 18.5 1.1 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 MitMem_reg PF13012.6 EEQ30648.1 - 0.00037 20.9 1.9 0.48 10.8 1.5 3.7 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function SecA_SW PF07516.13 EEQ30648.1 - 0.032 14.3 0.7 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 SecA Wing and Scaffold domain Cas9_PI PF16595.5 EEQ30648.1 - 0.062 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 Xrn1_D3 PF18194.1 EEQ30648.1 - 0.14 12.3 2.5 3.8 7.7 0.3 2.7 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 eIF-5a PF01287.20 EEQ30649.1 - 1.9e-27 95.1 2.1 2.8e-27 94.6 2.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EEQ30649.1 - 0.0089 16.0 0.3 0.018 15.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain zf-RRN7 PF11781.8 EEQ30650.1 - 6.6e-08 32.1 4.9 1.2e-07 31.2 4.9 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ribosomal_L40e PF01020.17 EEQ30651.1 - 3.8e-31 106.7 11.0 5.1e-31 106.3 11.0 1.2 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 EEQ30651.1 - 1.2e-20 73.0 0.0 1.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EEQ30651.1 - 3.5e-08 33.2 0.0 4.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Yip1 PF04893.17 EEQ30652.1 - 5.7e-15 55.4 16.0 1.1e-14 54.6 15.9 1.5 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 EEQ30652.1 - 0.13 11.7 4.9 0.22 11.0 2.2 2.2 1 1 1 2 2 2 0 YIF1 DUF5585 PF17823.1 EEQ30652.1 - 0.26 10.2 0.1 0.37 9.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) p53-inducible11 PF14936.6 EEQ30652.1 - 0.62 10.1 4.1 0.89 9.6 4.1 1.2 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 DUF2070 PF09843.9 EEQ30652.1 - 4.7 5.4 6.7 5.9 5.1 6.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RabGAP-TBC PF00566.18 EEQ30653.1 - 5.1e-24 85.1 0.1 7.5e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 EEQ30654.1 - 8.3e-66 222.6 0.0 8.8e-63 212.6 0.0 3.2 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.27 EEQ30655.1 - 3.1e-34 118.2 0.1 5.6e-33 114.1 0.1 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EEQ30655.1 - 7.2e-21 74.3 0.1 2.2e-20 72.8 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EEQ30655.1 - 7.9e-10 39.0 4.1 7.9e-10 39.0 0.1 3.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EEQ30655.1 - 1.2e-09 37.9 0.0 3.7e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EEQ30655.1 - 5.5e-07 29.7 0.5 1.1e-05 25.5 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EEQ30655.1 - 0.00067 19.9 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EEQ30655.1 - 0.0064 16.3 0.0 0.028 14.2 0.0 2.2 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 EEQ30655.1 - 0.049 13.2 0.0 0.28 10.8 0.0 2.5 1 1 0 1 1 1 0 Ras family Rhodanese PF00581.20 EEQ30656.1 - 6.4e-10 39.5 0.0 1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DUF4267 PF14087.6 EEQ30656.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) p450 PF00067.22 EEQ30657.1 - 7.4e-53 179.9 0.0 1.3e-52 179.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EEQ30659.1 - 3.1e-47 160.6 0.5 4.6e-47 160.0 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ30659.1 - 9.7e-33 113.7 0.7 1.4e-32 113.2 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ30659.1 - 2.3e-11 43.9 0.2 3.4e-11 43.4 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EEQ30659.1 - 1.4e-06 27.9 0.0 2.8e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EEQ30659.1 - 0.0013 18.2 0.2 0.0047 16.4 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EEQ30659.1 - 0.0033 16.6 0.1 0.0047 16.1 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EEQ30659.1 - 0.0064 16.4 0.4 0.013 15.4 0.4 1.6 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EEQ30659.1 - 0.077 12.1 0.2 0.17 11.0 0.2 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EEQ30659.1 - 0.16 11.4 0.3 0.29 10.5 0.1 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Methyltransf_2 PF00891.18 EEQ30660.1 - 8.2e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EEQ30660.1 - 0.003 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain adh_short PF00106.25 EEQ30661.1 - 7.5e-36 123.4 0.0 1.1e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ30661.1 - 5.9e-25 88.2 0.0 8.2e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ30661.1 - 1.7e-06 28.1 0.0 3.6e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ30661.1 - 0.00033 20.2 0.0 0.0006 19.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EEQ30661.1 - 0.0013 17.9 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EEQ30661.1 - 0.011 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 EEQ30661.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyoxalase_6 PF18029.1 EEQ30662.1 - 3.5e-05 24.5 0.1 6.4e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EEQ30662.1 - 0.0003 21.0 0.0 0.0015 18.8 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3390 PF11870.8 EEQ30662.1 - 0.12 12.7 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) SRP68 PF16969.5 EEQ30663.1 - 5.6e-185 616.5 4.6 6.4e-185 616.4 4.6 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 CENP-O PF09496.10 EEQ30663.1 - 0.014 15.4 3.3 1.3 8.9 0.1 2.9 2 1 1 3 3 3 0 Cenp-O kinetochore centromere component PPR PF01535.20 EEQ30664.1 - 1.1e-19 69.2 2.9 0.00031 20.8 0.0 8.5 8 0 0 8 8 8 4 PPR repeat PPR_2 PF13041.6 EEQ30664.1 - 2.3e-17 62.9 5.6 8e-08 32.4 0.0 7.7 5 2 5 10 10 10 3 PPR repeat family PPR_3 PF13812.6 EEQ30664.1 - 2.7e-14 53.0 0.3 3.5e-05 23.8 0.0 5.0 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EEQ30664.1 - 4.9e-08 32.6 0.0 1.5e-06 27.7 0.0 3.0 1 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EEQ30664.1 - 5.9e-05 22.7 0.0 21 4.9 0.0 5.8 6 0 0 6 6 6 1 PPR repeat TPR_15 PF13429.6 EEQ30664.1 - 0.0017 17.6 0.4 0.97 8.6 0.0 4.2 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ30664.1 - 0.077 13.7 0.0 14 6.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2811 PF10929.8 EEQ30664.1 - 0.14 12.4 0.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) MCM PF00493.23 EEQ30665.1 - 2.6e-97 324.3 0.1 3.8e-97 323.8 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEQ30665.1 - 5.3e-29 100.6 0.0 1.3e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEQ30665.1 - 2.9e-24 85.3 0.6 9.6e-24 83.6 0.6 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ30665.1 - 7.4e-12 45.8 0.0 2.2e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ30665.1 - 1.2e-06 28.0 0.0 1.4e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EEQ30665.1 - 0.0025 17.7 0.0 0.0072 16.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEQ30665.1 - 0.094 12.4 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Apt1 PF10351.9 EEQ30665.1 - 0.55 9.0 7.7 0.83 8.4 7.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spo7 PF03907.13 EEQ30666.1 - 1.1e-88 296.4 0.0 1.7e-88 295.8 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein YL1 PF05764.13 EEQ30666.1 - 0.055 13.6 6.1 0.11 12.6 6.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein ABC_tran_Xtn PF12848.7 EEQ30666.1 - 5.5 7.1 8.3 1 9.4 4.6 1.6 2 0 0 2 2 2 0 ABC transporter Abhydrolase_1 PF00561.20 EEQ30667.1 - 1.3e-20 74.1 0.0 1.6e-19 70.5 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ30667.1 - 6.9e-16 58.2 0.0 4.2e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ30667.1 - 1.1e-15 58.8 8.7 4e-14 53.8 8.7 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EEQ30667.1 - 8e-05 22.4 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 EEQ30667.1 - 0.0005 19.5 0.0 0.00096 18.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 EEQ30667.1 - 0.0039 17.1 0.0 0.067 13.0 0.0 2.4 2 0 0 2 2 2 1 Serine hydrolase LIDHydrolase PF10230.9 EEQ30667.1 - 0.004 16.7 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 EEQ30667.1 - 0.0051 15.8 0.0 0.0075 15.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EEQ30667.1 - 0.0099 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.13 EEQ30667.1 - 0.018 14.9 0.0 0.074 12.9 0.0 2.0 2 1 1 3 3 3 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EEQ30667.1 - 0.028 14.6 0.3 0.16 12.1 0.3 2.2 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 EEQ30667.1 - 0.031 14.1 0.0 3.4 7.4 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EEQ30667.1 - 0.038 13.7 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EEQ30667.1 - 0.049 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 EEQ30667.1 - 0.094 12.2 0.0 0.46 9.9 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family TatD_DNase PF01026.21 EEQ30668.1 - 3.8e-37 128.0 0.0 5.5e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase TPP_enzyme_N PF02776.18 EEQ30669.1 - 6.6e-31 107.2 0.5 5e-27 94.6 0.1 3.6 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EEQ30669.1 - 2.6e-20 72.8 0.0 4.8e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEQ30669.1 - 1.1e-11 44.6 0.0 4.2e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.7 EEQ30669.1 - 0.1 13.0 0.3 3.4 8.0 0.1 3.0 2 1 0 2 2 2 0 MobA-like NTP transferase domain Chitin_synth_2 PF03142.15 EEQ30670.1 - 8.4e-230 763.8 0.1 1.3e-229 763.3 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 EEQ30670.1 - 1.5e-17 63.5 0.1 1.3e-11 44.4 0.0 2.9 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EEQ30670.1 - 2e-16 59.6 0.2 7.1e-16 57.9 0.2 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EEQ30670.1 - 3e-13 50.1 3.2 8.2e-13 48.7 3.2 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EEQ30670.1 - 9.2e-13 48.6 0.1 1.3e-11 44.9 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 EEQ30670.1 - 1e-08 34.0 0.0 1.5e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) Glyco_transf_21 PF13506.6 EEQ30670.1 - 4.9e-05 22.9 0.1 0.0079 15.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EEQ30670.1 - 0.00086 19.2 0.0 0.42 10.4 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Chitin_synth_2 PF03142.15 EEQ30672.1 - 2.4e-246 818.5 0.6 3.5e-246 817.9 0.6 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EEQ30672.1 - 1e-70 238.8 0.0 6.8e-70 236.1 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 EEQ30672.1 - 2.9e-20 72.2 0.3 1.7e-14 53.7 0.0 3.6 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EEQ30672.1 - 5e-15 55.2 0.4 1.3e-14 53.9 0.4 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EEQ30672.1 - 1.2e-12 48.2 6.0 2.9e-12 46.9 6.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EEQ30672.1 - 2.6e-10 40.6 0.2 2.3e-09 37.5 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EEQ30672.1 - 0.0003 20.7 0.0 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EEQ30672.1 - 0.0014 18.1 0.2 0.049 13.1 0.2 2.8 2 1 0 2 2 2 1 Glycosyl transferase family 21 AAA_16 PF13191.6 EEQ30672.1 - 0.053 13.9 0.1 0.22 11.9 0.1 2.0 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ30672.1 - 0.065 13.1 0.0 0.33 10.9 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase KH_1 PF00013.29 EEQ30673.1 - 1.5e-28 98.4 0.5 3.8e-06 26.6 0.1 6.3 6 0 0 6 6 6 5 KH domain Gly_acyl_tr_C PF08444.10 EEQ30673.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.0 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region SUV3_C PF12513.8 EEQ30673.1 - 0.18 11.7 0.1 0.43 10.6 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal SelP_N PF04592.14 EEQ30673.1 - 3 7.2 16.2 5.3 6.4 16.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Hydrolase PF00702.26 EEQ30674.1 - 3.3e-08 34.1 0.0 1.2e-07 32.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ30674.1 - 2.6e-07 30.9 0.0 4e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ30674.1 - 0.063 13.3 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 HAD-hyrolase-like Dynactin PF12455.8 EEQ30676.1 - 9.3e-102 340.1 2.4 9.3e-102 340.1 2.4 3.6 3 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 EEQ30676.1 - 3.4e-20 71.8 0.1 5.7e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain APG6_N PF17675.1 EEQ30676.1 - 0.0088 16.6 0.6 0.0088 16.6 0.6 8.2 4 2 3 7 7 7 1 Apg6 coiled-coil region HALZ PF02183.18 EEQ30676.1 - 4.9 7.5 36.9 0.73 10.1 0.2 7.9 5 1 2 7 7 7 0 Homeobox associated leucine zipper Beta_elim_lyase PF01212.21 EEQ30677.1 - 1.7e-41 142.5 0.1 4.9e-30 104.8 0.0 2.1 2 0 0 2 2 2 2 Beta-eliminating lyase Solute_trans_a PF03619.16 EEQ30679.1 - 2.7e-63 214.0 2.9 5.1e-63 213.1 2.9 1.4 1 1 0 1 1 1 1 Organic solute transporter Ostalpha GTP_EFTU PF00009.27 EEQ30681.1 - 4.1e-67 225.5 0.1 5.6e-67 225.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EEQ30681.1 - 1e-29 102.8 0.0 8e-29 99.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EEQ30681.1 - 3.3e-21 75.1 0.0 1.1e-20 73.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEQ30681.1 - 3.4e-13 49.8 0.1 1.4e-12 47.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EEQ30681.1 - 5.4e-12 45.6 0.0 1.5e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EEQ30681.1 - 0.00011 22.2 0.1 0.00024 21.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PWI PF01480.17 EEQ30682.1 - 2.3e-10 40.6 0.3 5.4e-10 39.4 0.3 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EEQ30682.1 - 3.3e-07 30.0 0.1 2.3e-05 24.1 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEQ30682.1 - 5.6e-07 29.5 0.0 9e-06 25.6 0.1 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EEQ30682.1 - 0.00039 20.3 0.8 0.00065 19.6 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_occluded PF16842.5 EEQ30682.1 - 0.036 13.9 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif zf_CCCH_4 PF18345.1 EEQ30682.1 - 0.058 13.5 0.5 0.1 12.7 0.5 1.4 1 0 0 1 1 1 0 Zinc finger domain Borrelia_P83 PF05262.11 EEQ30682.1 - 0.35 9.3 6.8 0.48 8.9 6.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ARGLU PF15346.6 EEQ30682.1 - 1 9.2 18.5 0.58 10.0 15.9 1.8 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 AP-5_subunit_s1 PF15001.6 EEQ30682.1 - 2 8.4 6.1 3.4 7.6 6.1 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 PHM7_cyt PF14703.6 EEQ30682.1 - 2.7 8.2 6.8 3.4 7.9 0.1 2.7 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter HNH_2 PF13391.6 EEQ30683.1 - 4.4e-15 55.6 0.0 8.6e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease AHH PF14412.6 EEQ30683.1 - 0.019 15.0 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH MFS_1 PF07690.16 EEQ30684.1 - 6.8e-37 127.2 15.5 1.4e-36 126.1 15.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ30684.1 - 9.3e-09 34.6 15.3 2.3e-08 33.4 14.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EEQ30684.1 - 0.00057 18.9 11.4 0.002 17.1 11.4 1.8 1 1 0 1 1 1 1 MFS_1 like family DctQ PF04290.12 EEQ30684.1 - 0.014 15.3 0.1 0.014 15.3 0.1 2.9 3 1 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component CitMHS PF03600.16 EEQ30684.1 - 2.6 7.2 18.0 3.8 6.6 8.8 2.4 1 1 1 2 2 2 0 Citrate transporter RIBIOP_C PF04950.12 EEQ30686.1 - 6.7e-95 317.9 0.0 6.7e-95 317.9 0.0 2.0 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EEQ30686.1 - 3.3e-29 100.8 0.0 8.4e-29 99.5 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EEQ30686.1 - 3.5e-05 24.1 0.0 9.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EEQ30686.1 - 4e-05 23.3 0.0 0.0068 16.0 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EEQ30686.1 - 0.00018 22.0 0.0 0.00044 20.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ30686.1 - 0.00024 21.5 0.0 0.00082 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EEQ30686.1 - 0.0014 18.7 0.1 0.0045 17.1 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EEQ30686.1 - 0.0014 19.1 1.1 0.033 14.7 0.1 3.5 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 EEQ30686.1 - 0.0021 17.8 0.0 0.0096 15.7 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 EEQ30686.1 - 0.0026 17.0 0.0 0.0059 15.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 EEQ30686.1 - 0.0037 16.8 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EEQ30686.1 - 0.0082 16.5 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase cobW PF02492.19 EEQ30686.1 - 0.0083 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EEQ30686.1 - 0.015 15.3 0.4 0.031 14.2 0.4 1.5 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 EEQ30686.1 - 0.025 14.5 1.1 0.041 13.8 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EEQ30686.1 - 0.03 14.8 2.1 0.032 14.7 0.1 2.0 2 0 0 2 2 1 0 ABC transporter AAA_33 PF13671.6 EEQ30686.1 - 0.031 14.4 0.0 0.031 14.4 0.0 2.5 3 0 0 3 3 1 0 AAA domain Roc PF08477.13 EEQ30686.1 - 0.036 14.3 0.1 0.16 12.2 0.1 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 EEQ30686.1 - 0.042 14.2 0.2 0.087 13.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEQ30686.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ30686.1 - 0.045 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EEQ30686.1 - 0.05 13.6 0.2 0.19 11.7 0.1 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EEQ30686.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain KAP_NTPase PF07693.14 EEQ30686.1 - 0.072 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain MobB PF03205.14 EEQ30686.1 - 0.087 12.7 0.1 0.42 10.5 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 EEQ30686.1 - 0.11 12.4 0.1 0.31 10.9 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase SRPRB PF09439.10 EEQ30686.1 - 0.14 11.5 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EEQ30686.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 EEQ30686.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PA28_alpha PF02251.18 EEQ30686.1 - 0.16 12.0 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit AAA_11 PF13086.6 EEQ30686.1 - 0.24 11.2 0.1 0.24 11.2 0.1 3.1 4 0 0 4 4 3 0 AAA domain Aminotran_1_2 PF00155.21 EEQ30687.1 - 8.4e-41 140.3 0.0 1e-40 140.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Dendrin PF15498.6 EEQ30688.1 - 0.00062 18.6 4.0 0.0011 17.9 4.0 1.3 1 0 0 1 1 1 1 Nephrin and CD2AP-binding protein, Dendrin CDC24_OB3 PF17244.2 EEQ30688.1 - 0.05 13.3 0.3 0.07 12.8 0.3 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 NUDE_C PF04880.13 EEQ30688.1 - 0.47 10.9 9.8 1.9 9.0 3.6 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Dicty_REP PF05086.12 EEQ30688.1 - 0.94 7.4 4.8 1.2 7.0 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 EEQ30688.1 - 1.7 6.7 18.4 2.5 6.2 18.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EEQ30688.1 - 2 8.4 20.2 0.41 10.6 16.2 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF515 PF04415.12 EEQ30688.1 - 2.3 6.5 9.9 3.5 5.9 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.9 EEQ30688.1 - 4.8 6.7 14.7 0.035 13.7 6.3 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MAGE_N PF12440.8 EEQ30688.1 - 6.1 7.6 20.6 1.6 9.5 9.0 2.5 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF1989 PF09347.10 EEQ30690.1 - 1.8e-64 216.4 0.0 2.2e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Abhydrolase_1 PF00561.20 EEQ30691.1 - 2e-14 53.8 0.0 3.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ30691.1 - 7.6e-12 46.3 0.0 1e-11 45.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ30691.1 - 1.3e-08 34.4 0.0 4.4e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EEQ30691.1 - 0.00051 19.9 0.0 4 7.2 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase PDZ_3 PF17815.1 EEQ30691.1 - 0.062 13.2 0.1 0.094 12.6 0.1 1.3 1 0 0 1 1 1 0 PDZ domain NADH_Oxid_Nqo15 PF11497.8 EEQ30691.1 - 0.081 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 DUF3425 PF11905.8 EEQ30692.1 - 2.4e-11 43.7 3.2 4.8e-10 39.5 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3425) MRP-L28 PF09812.9 EEQ30692.1 - 0.021 15.0 2.1 0.034 14.3 2.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 bZIP_1 PF00170.21 EEQ30692.1 - 0.067 13.3 8.7 0.11 12.7 8.7 1.2 1 0 0 1 1 1 0 bZIP transcription factor Peptidase_S31 PF05578.12 EEQ30693.1 - 0.041 13.4 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 BCDHK_Adom3 PF10436.9 EEQ30694.1 - 1.9e-46 157.9 0.0 2.6e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EEQ30694.1 - 2.8e-09 37.4 0.0 8.9e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EEQ30694.1 - 0.0081 16.1 0.0 0.03 14.3 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain MFS_1 PF07690.16 EEQ30695.1 - 8.8e-21 74.2 39.4 3.2e-19 69.1 39.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ30695.1 - 0.021 13.3 21.2 0.049 12.1 20.9 1.7 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 EEQ30695.1 - 0.16 12.1 4.2 0.24 11.6 0.1 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 TMEM100 PF16311.5 EEQ30695.1 - 5.4 6.6 5.7 8.2 6.0 1.0 2.8 3 0 0 3 3 3 0 Transmembrane protein 100 DUF1349 PF07081.11 EEQ30696.1 - 2.8e-33 115.1 0.0 3.3e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) HTH_29 PF13551.6 EEQ30696.1 - 0.2 11.7 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Ras PF00071.22 EEQ30697.1 - 8.9e-53 178.2 0.0 1e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ30697.1 - 6.1e-19 68.4 0.0 8.7e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ30697.1 - 4.4e-06 26.3 0.0 6.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.21 EEQ30698.1 - 1.6e-86 290.3 0.1 1.9e-86 290.0 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EEQ30698.1 - 0.0025 18.1 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 UPF0489 domain ketoacyl-synt PF00109.26 EEQ30699.1 - 3.3e-60 203.8 0.4 1.9e-59 201.3 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EEQ30699.1 - 1.3e-35 122.0 0.6 2.1e-35 121.3 0.6 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EEQ30699.1 - 3.6e-05 23.2 1.0 0.00084 18.8 0.2 2.6 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EEQ30699.1 - 0.066 12.9 5.3 0.15 11.7 0.4 3.1 3 1 0 3 3 3 0 Thiolase, C-terminal domain Lactamase_B_2 PF12706.7 EEQ30700.1 - 5.3e-10 39.1 1.0 1.7e-08 34.2 1.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EEQ30700.1 - 0.001 19.0 2.1 0.01 15.7 2.1 2.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF2157 PF09925.9 EEQ30701.1 - 0.0042 16.9 0.8 0.0042 16.9 0.8 2.9 1 1 1 2 2 2 1 Predicted membrane protein (DUF2157) DUF2627 PF11118.8 EEQ30701.1 - 0.047 14.3 4.6 0.22 12.1 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Jagunal PF07086.12 EEQ30701.1 - 0.097 12.7 5.0 1.4 9.0 0.4 3.0 1 1 2 3 3 3 0 Jagunal, ER re-organisation during oogenesis MIG-14_Wnt-bd PF06664.12 EEQ30701.1 - 1.5 8.0 11.3 76 2.4 11.3 2.2 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion p450 PF00067.22 EEQ30702.1 - 1.7e-46 158.9 0.0 3e-46 158.1 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Vint PF14623.6 EEQ30703.1 - 2.6e-62 209.5 0.0 1.4e-61 207.2 0.0 2.2 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.6 EEQ30703.1 - 7.7e-27 93.2 0.0 1.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 EEQ30703.1 - 3.4e-16 60.0 0.0 2.3e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EEQ30703.1 - 1.1e-11 45.4 0.1 3.2e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 EEQ30703.1 - 1e-10 41.7 0.1 1.7e-09 37.8 0.1 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain ABC_membrane PF00664.23 EEQ30704.1 - 2.5e-104 348.8 24.6 5.1e-56 190.3 5.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ30704.1 - 1.7e-67 226.2 0.0 1.1e-33 116.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ30704.1 - 1.4e-13 50.8 0.5 0.00016 21.2 0.4 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EEQ30704.1 - 6.4e-08 33.0 0.2 0.029 14.6 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEQ30704.1 - 2.3e-06 28.1 1.4 0.067 13.6 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EEQ30704.1 - 5.5e-06 26.0 5.6 0.0012 18.6 0.2 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ30704.1 - 1.1e-05 25.3 0.2 0.12 12.3 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_30 PF13604.6 EEQ30704.1 - 5.7e-05 22.9 0.4 0.48 10.1 0.0 3.0 3 1 0 3 3 2 2 AAA domain ABC_ATPase PF09818.9 EEQ30704.1 - 5.9e-05 22.0 0.5 0.44 9.3 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_18 PF13238.6 EEQ30704.1 - 0.00013 22.5 0.0 0.16 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EEQ30704.1 - 0.00016 21.1 0.0 0.014 14.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 EEQ30704.1 - 0.00018 21.4 3.6 0.45 10.3 0.3 3.8 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EEQ30704.1 - 0.00041 20.0 0.5 0.48 10.0 0.0 3.1 4 0 0 4 4 4 1 AAA domain AAA_15 PF13175.6 EEQ30704.1 - 0.00043 20.1 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EEQ30704.1 - 0.00097 19.6 1.1 0.16 12.4 0.1 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEQ30704.1 - 0.00098 19.1 0.3 0.55 10.2 0.0 3.3 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EEQ30704.1 - 0.0011 19.0 0.0 0.078 12.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_23 PF13476.6 EEQ30704.1 - 0.0013 19.3 0.6 0.68 10.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EEQ30704.1 - 0.0032 17.1 0.1 2.8 7.5 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_7 PF12775.7 EEQ30704.1 - 0.0037 16.8 0.0 0.84 9.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 EEQ30704.1 - 0.0048 17.1 0.1 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EEQ30704.1 - 0.0072 16.1 0.2 0.55 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EEQ30704.1 - 0.0081 16.4 0.6 3.1 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 EEQ30704.1 - 0.014 14.6 0.0 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit SbcCD_C PF13558.6 EEQ30704.1 - 0.02 15.1 3.5 1.3 9.3 0.8 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 EEQ30704.1 - 0.022 14.5 0.1 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ACR_tran PF00873.19 EEQ30704.1 - 0.044 11.4 0.2 0.074 10.7 0.2 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Dala_Dala_lig_N PF01820.21 EEQ30704.1 - 0.044 14.2 0.0 5.2 7.6 0.0 2.8 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus AAA_14 PF13173.6 EEQ30704.1 - 0.069 13.2 0.0 17 5.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_2 PF07724.14 EEQ30704.1 - 0.098 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EEQ30704.1 - 0.11 12.2 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EEQ30704.1 - 0.13 12.6 0.1 8.2 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 EEQ30704.1 - 0.14 11.3 0.6 6.7 5.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 EEQ30704.1 - 0.14 12.2 0.3 30 4.7 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase PF06745.13 EEQ30704.1 - 0.28 10.5 1.4 11 5.2 0.1 2.3 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 EEQ30704.1 - 0.84 10.1 3.4 14 6.1 0.0 3.5 5 0 0 5 5 2 0 AAA domain Tetraspanin PF00335.20 EEQ30704.1 - 7.2 6.3 7.5 7.2 6.3 0.1 3.4 3 0 0 3 3 3 0 Tetraspanin family CAP59_mtransfer PF11735.8 EEQ30705.1 - 4.3e-74 249.2 0.0 5.9e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Stk19 PF10494.9 EEQ30706.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 GST_N PF02798.20 EEQ30711.1 - 4.2e-16 59.1 0.0 8.1e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ30711.1 - 5.2e-14 52.4 0.0 9.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EEQ30711.1 - 1e-09 38.5 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EEQ30711.1 - 1.5e-09 38.0 0.0 3.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEQ30711.1 - 2.6e-09 37.2 0.0 5.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ30711.1 - 7.2e-05 22.7 0.0 0.00021 21.2 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain APH PF01636.23 EEQ30712.1 - 3.1e-05 24.0 0.3 0.00012 22.1 0.3 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ30712.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEQ30712.1 - 0.026 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Iwr1 PF08574.10 EEQ30714.1 - 1.3e-18 67.8 7.8 1.3e-18 67.8 7.8 3.2 2 1 1 3 3 3 1 Transcription factor Iwr1 Eapp_C PF10238.9 EEQ30714.1 - 0.12 12.5 0.8 0.39 10.8 0.8 1.9 1 0 0 1 1 1 0 E2F-associated phosphoprotein YfhD PF14151.6 EEQ30714.1 - 2 8.6 6.4 0.88 9.8 0.2 3.2 3 0 0 3 3 3 0 YfhD-like protein RRM_1 PF00076.22 EEQ30715.1 - 2.3e-39 133.0 0.0 5.3e-12 45.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ30715.1 - 5.4e-14 51.8 0.0 0.0053 16.6 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 EEQ30715.1 - 7.4e-06 25.6 6.1 7.4e-06 25.6 6.1 3.1 3 1 0 3 3 3 1 Putative RRM domain DUF4523 PF15023.6 EEQ30715.1 - 4.8e-05 23.2 0.0 0.72 9.7 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 EEQ30715.1 - 9.3e-05 22.5 0.0 0.26 11.4 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 EEQ30715.1 - 0.00041 20.3 0.0 0.65 10.1 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif YL1 PF05764.13 EEQ30716.1 - 2.4e-63 214.5 31.1 2.4e-63 214.5 31.1 2.0 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 EEQ30716.1 - 3.8e-13 48.9 0.6 6.8e-13 48.1 0.6 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain ATP-synt_E PF05680.12 EEQ30716.1 - 4.6 7.6 12.4 0.49 10.8 0.5 3.0 2 0 0 2 2 2 0 ATP synthase E chain tRNA-synt_2 PF00152.20 EEQ30718.1 - 6.2e-91 304.7 0.0 8.8e-91 304.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ30718.1 - 1.2e-07 31.6 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF818 PF05677.12 EEQ30719.1 - 0.66 8.9 3.6 0.58 9.0 2.3 1.5 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) DUF3989 PF13150.6 EEQ30719.1 - 0.91 9.3 3.4 14 5.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) PUF PF00806.19 EEQ30720.1 - 1.5e-28 96.9 0.0 1.5e-05 24.4 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EEQ30720.1 - 6.4e-11 41.9 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MT-A70 PF05063.14 EEQ30722.1 - 1.4e-23 83.7 0.0 2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Peptidase_C12 PF01088.21 EEQ30723.1 - 4.3e-55 186.7 0.0 5.1e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DcpS PF05652.12 EEQ30724.1 - 3.8e-32 111.2 0.0 6.4e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EEQ30724.1 - 2.1e-31 108.7 0.3 3.2e-31 108.2 0.3 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Alk_phosphatase PF00245.20 EEQ30725.1 - 7.1e-70 236.0 2.0 3.4e-69 233.8 2.0 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EEQ30725.1 - 3.3e-07 30.0 2.4 1.8e-06 27.6 2.3 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EEQ30725.1 - 2e-05 24.4 1.1 3.1e-05 23.7 1.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EEQ30725.1 - 0.0052 15.4 0.1 0.0099 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 EEQ30725.1 - 0.05 13.0 0.7 0.11 11.8 0.2 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily RNase_H2_suC PF08615.11 EEQ30726.1 - 2.1e-25 89.5 0.6 2.6e-25 89.2 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.24 EEQ30727.1 - 4e-19 69.8 0.0 8.8e-19 68.6 0.0 1.6 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EEQ30727.1 - 0.032 14.0 0.0 0.088 12.5 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease Nop53 PF07767.11 EEQ30728.1 - 3e-98 329.8 38.0 4.4e-98 329.3 38.0 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Myb_Cef PF11831.8 EEQ30729.1 - 3e-51 174.3 6.1 3e-51 174.3 6.1 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EEQ30729.1 - 1.8e-21 76.1 6.1 2.1e-10 40.6 0.7 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ30729.1 - 1.7e-19 69.8 4.8 1.5e-12 47.5 1.4 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EEQ30729.1 - 0.055 13.6 0.2 1 9.5 0.0 2.8 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MOZ_SAS PF01853.18 EEQ30730.1 - 5.4e-75 251.0 0.0 8.8e-75 250.3 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 EEQ30730.1 - 1.6e-23 82.3 0.0 2.9e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 EEQ30730.1 - 2.7e-22 78.1 0.3 5.4e-22 77.2 0.3 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EEQ30730.1 - 0.005 17.3 0.0 0.0095 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1918 PF08940.11 EEQ30730.1 - 0.026 14.2 0.0 0.089 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Acetyltransf_1 PF00583.25 EEQ30730.1 - 0.037 14.3 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Histone_HNS PF00816.21 EEQ30731.1 - 0.76 10.6 9.7 1.2 10.0 1.3 3.2 2 0 0 2 2 2 0 H-NS histone family Orthopox_C10L PF07020.11 EEQ30731.1 - 5.8 7.7 6.9 1e+02 3.7 0.1 3.4 2 1 0 2 2 2 0 Orthopoxvirus C10L protein F1F0-ATPsyn_F PF10791.9 EEQ30732.1 - 6.3e-39 132.3 0.1 7.1e-39 132.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 EEQ30732.1 - 0.0083 16.5 0.0 0.0096 16.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.12 EEQ30733.1 - 8.4e-33 112.5 1.8 1.3e-32 111.9 1.8 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Nipped-B_C PF12830.7 EEQ30734.1 - 7.7e-47 159.7 1.2 7.7e-47 159.7 1.2 4.1 5 1 0 5 5 5 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EEQ30734.1 - 1.2e-10 41.4 2.5 1.2e-10 41.4 2.5 2.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 EEQ30734.1 - 1.9e-05 24.0 2.5 0.12 11.5 0.0 3.1 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 EEQ30734.1 - 9.8e-05 22.4 8.7 0.013 15.5 0.1 3.9 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EEQ30734.1 - 0.0041 17.3 4.7 0.82 10.1 0.3 5.4 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EEQ30734.1 - 0.098 13.3 0.7 2 9.0 0.2 3.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EEQ30734.1 - 0.55 8.7 14.5 0.42 9.1 1.1 3.9 2 1 2 4 4 4 0 Adaptin N terminal region Methyltransf_25 PF13649.6 EEQ30735.1 - 7.2e-18 65.1 0.1 3.3e-11 43.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ30735.1 - 1.1e-16 61.3 0.1 5.5e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ30735.1 - 3.1e-14 53.1 0.0 3.2e-08 33.6 0.0 3.1 2 1 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ30735.1 - 2.6e-09 37.7 0.1 2.9e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ30735.1 - 2.8e-08 33.4 0.0 0.0036 16.7 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EEQ30735.1 - 3.7e-08 33.3 0.0 8.1e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EEQ30735.1 - 0.00043 19.9 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW UPF0146 PF03686.13 EEQ30735.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) MTS PF05175.14 EEQ30735.1 - 0.0053 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EEQ30735.1 - 0.0083 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 EEQ30735.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 EEQ30735.1 - 0.032 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 EEQ30735.1 - 0.042 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 3HCDH_N PF02737.18 EEQ30735.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_32 PF13679.6 EEQ30735.1 - 0.2 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TFIIS_C PF01096.18 EEQ30736.1 - 2.6e-15 56.0 2.1 2.6e-15 56.0 2.1 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EEQ30736.1 - 3.2e-06 26.9 0.9 3.2e-06 26.9 0.9 2.8 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Ribosomal_S27e PF01667.17 EEQ30736.1 - 0.0087 15.7 3.5 4.5 7.0 0.0 3.7 3 1 1 4 4 4 1 Ribosomal protein S27 RecR PF02132.15 EEQ30736.1 - 0.042 13.4 0.7 0.042 13.4 0.7 2.1 2 0 0 2 2 2 0 RecR protein zf-ribbon_3 PF13248.6 EEQ30736.1 - 0.046 13.1 7.8 7.5 6.1 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain NMD3 PF04981.13 EEQ30736.1 - 0.071 12.6 0.3 0.071 12.6 0.3 2.1 1 1 1 2 2 2 0 NMD3 family zf-RING_7 PF02591.15 EEQ30736.1 - 0.091 13.0 7.6 2.1 8.6 0.1 3.5 3 1 1 4 4 4 0 C4-type zinc ribbon domain Zn_ribbon_recom PF13408.6 EEQ30736.1 - 0.091 13.3 7.1 0.67 10.5 0.1 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DZR PF12773.7 EEQ30736.1 - 0.2 11.7 10.2 38 4.4 10.2 2.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_5 PF14634.6 EEQ30736.1 - 0.27 11.2 6.1 15 5.6 0.5 3.2 3 0 0 3 3 3 0 zinc-RING finger domain Zn-ribbon_8 PF09723.10 EEQ30736.1 - 0.34 11.0 8.1 2.2 8.5 0.1 3.2 3 0 0 3 3 3 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 EEQ30736.1 - 0.43 10.1 12.0 4.8 6.8 0.1 3.6 3 1 0 3 3 3 0 TFIIB zinc-binding DpnI PF06044.12 EEQ30736.1 - 0.52 9.9 2.5 0.6 9.7 0.1 2.0 1 1 1 2 2 2 0 Dam-replacing family OrfB_Zn_ribbon PF07282.11 EEQ30736.1 - 1 9.3 10.6 1.8 8.6 2.4 2.7 2 2 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 EEQ30736.1 - 1.1 9.1 12.8 14 5.6 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 EEQ30736.1 - 3.1 8.0 6.3 8.5 6.6 0.1 3.2 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HEAT_2 PF13646.6 EEQ30737.1 - 3.9e-31 107.3 5.8 9.2e-14 51.6 0.3 3.7 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 EEQ30737.1 - 4.4e-22 76.5 0.9 0.0032 18.0 0.0 6.4 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EEQ30737.1 - 2.8e-08 33.3 1.3 0.78 10.2 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EEQ30737.1 - 0.0022 18.5 10.6 0.54 10.8 0.0 5.5 3 3 4 7 7 7 2 HEAT-like repeat Arm PF00514.23 EEQ30737.1 - 0.0027 17.7 0.0 6 7.1 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EEQ30737.1 - 0.074 13.1 0.0 16 5.5 0.0 3.3 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Vitellogenin_N PF01347.22 EEQ30737.1 - 0.089 11.2 0.0 17 3.6 0.0 3.0 2 1 1 3 3 3 0 Lipoprotein amino terminal region DUF4777 PF16007.5 EEQ30737.1 - 0.24 11.7 1.2 22 5.4 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4777) Pyr_redox_2 PF07992.14 EEQ30738.1 - 9.7e-41 139.9 0.0 1.4e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ30738.1 - 2.2e-10 40.9 0.0 4.7e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EEQ30738.1 - 1.3e-05 24.4 0.1 4.6e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EEQ30738.1 - 0.0002 21.0 0.3 0.0006 19.5 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EEQ30738.1 - 0.0003 20.2 0.1 0.00074 18.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EEQ30738.1 - 0.0032 17.9 0.1 0.009 16.4 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 EEQ30738.1 - 0.27 11.2 1.1 3.3 7.7 0.0 2.9 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand CLTH PF10607.9 EEQ30739.1 - 8e-34 116.7 0.3 1.1e-33 116.2 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EEQ30739.1 - 5.5e-10 38.8 0.0 1.2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 LisH PRK PF00485.18 EEQ30740.1 - 8.5e-52 175.8 0.0 1.1e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EEQ30740.1 - 9.9e-06 26.1 0.0 1.6e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EEQ30740.1 - 5e-05 22.7 0.0 8.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 EEQ30740.1 - 0.0072 16.4 0.1 0.015 15.4 0.1 1.8 1 1 0 1 1 1 1 Helicase HerA, central domain CPT PF07931.12 EEQ30740.1 - 0.0078 16.1 0.0 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 EEQ30740.1 - 0.012 15.3 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase CbiA PF01656.23 EEQ30740.1 - 0.029 14.4 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 EEQ30740.1 - 0.079 13.4 0.0 3.1 8.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EEQ30740.1 - 0.096 12.8 0.0 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain NUC153 PF08159.12 EEQ30741.1 - 3.8e-15 55.4 8.7 1.5e-14 53.5 0.3 3.5 3 0 0 3 3 3 2 NUC153 domain ATP-synt_J PF04911.12 EEQ30741.1 - 0.031 13.8 0.3 0.25 10.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase j chain DUF4148 PF13663.6 EEQ30741.1 - 0.12 12.5 0.1 0.44 10.8 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Npa1 PF11707.8 EEQ30742.1 - 1.4e-94 317.2 1.2 2.5e-94 316.4 0.2 1.9 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EEQ30742.1 - 1.3e-59 201.2 0.7 7.9e-59 198.6 0.0 2.6 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 BACK PF07707.15 EEQ30742.1 - 1.8 8.7 4.2 2 8.6 0.2 2.6 2 0 0 2 2 2 0 BTB And C-terminal Kelch HA2 PF04408.23 EEQ30744.1 - 4e-24 85.0 0.1 1.1e-23 83.6 0.0 1.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EEQ30744.1 - 5e-19 68.5 0.0 9.2e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EEQ30745.1 - 0.00014 21.7 0.3 0.00038 20.3 0.3 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EEQ30745.1 - 0.00068 18.8 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EEQ30745.1 - 0.012 15.9 0.2 0.037 14.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EEQ30745.1 - 0.034 13.9 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EEQ30745.1 - 0.064 13.4 0.0 0.21 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ30745.1 - 0.064 13.6 0.9 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 EEQ30745.1 - 0.097 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EEQ30745.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 EEQ30745.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EEQ30745.1 - 0.2 11.2 0.1 0.33 10.5 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region SUV3_C PF12513.8 EEQ30746.1 - 2.1e-16 59.5 0.1 4.6e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EEQ30746.1 - 9.2e-11 42.1 0.0 2.6e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EEQ30746.1 - 0.0002 21.2 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF4771 PF15995.5 EEQ30746.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Sec1 PF00995.23 EEQ30747.1 - 6.3e-112 375.7 0.0 7.5e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Beta-Casp PF10996.8 EEQ30747.1 - 0.12 12.7 0.0 1.8 8.9 0.0 2.6 1 1 0 1 1 1 0 Beta-Casp domain HTH_micro PF17007.5 EEQ30747.1 - 0.13 11.1 0.5 0.23 10.3 0.1 1.5 2 0 0 2 2 2 0 HTH-like G-patch PF01585.23 EEQ30748.1 - 2.5e-06 27.3 0.1 5.6e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.25 EEQ30749.1 - 2.2e-13 50.1 0.0 9.1e-11 41.6 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ30749.1 - 9.4e-06 25.3 0.0 4.7e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ30749.1 - 1.8e-05 24.8 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ30749.1 - 6.2e-05 22.6 0.0 0.00013 21.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4235 PF14019.6 EEQ30749.1 - 0.47 10.6 4.6 0.24 11.5 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) GDP_Man_Dehyd PF16363.5 EEQ30750.1 - 7.6e-50 170.2 0.0 2e-49 168.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EEQ30750.1 - 3e-48 164.4 0.0 4.2e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ30750.1 - 1.5e-14 53.7 0.0 2.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EEQ30750.1 - 5e-12 45.6 0.0 5.8e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EEQ30750.1 - 3.7e-11 42.6 0.0 5.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EEQ30750.1 - 2.1e-10 40.4 0.0 3.6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ30750.1 - 2.1e-06 27.8 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EEQ30750.1 - 1.4e-05 24.8 0.0 3.8e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 EEQ30750.1 - 0.00028 20.1 0.0 0.033 13.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EEQ30750.1 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 EEQ30750.1 - 0.0081 15.8 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 EEQ30750.1 - 0.0086 15.7 0.0 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.18 EEQ30750.1 - 0.036 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EEQ30751.1 - 3.3e-23 82.5 0.0 4.5e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ30751.1 - 3.2e-09 36.7 0.0 4.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EEQ30751.1 - 4e-06 26.5 0.0 6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ30751.1 - 0.0014 17.7 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EEQ30751.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FIST_C PF10442.9 EEQ30751.1 - 0.05 13.6 0.0 0.19 11.7 0.0 1.9 1 1 0 1 1 1 0 FIST C domain PAT1 PF09770.9 EEQ30752.1 - 9.1e-271 901.0 25.1 2.5e-144 482.7 23.9 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 GGACT PF06094.12 EEQ30753.1 - 5.1e-14 52.9 0.0 6.3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like GRIP PF01465.20 EEQ30753.1 - 0.026 14.5 0.1 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 GRIP domain Glyco_transf_15 PF01793.16 EEQ30754.1 - 2.8e-128 427.8 12.1 3.4e-128 427.5 12.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 EEQ30755.1 - 2.7e-30 104.3 1.7 3.6e-30 103.9 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 HTH_Tnp_IS1 PF12759.7 EEQ30755.1 - 0.034 13.8 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 InsA C-terminal domain DUF3772 PF12607.8 EEQ30755.1 - 0.42 10.4 1.9 2 8.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) UMP1 PF05348.11 EEQ30756.1 - 3.5e-38 130.5 0.1 4.5e-38 130.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 IML1 PF12257.8 EEQ30758.1 - 2.1e-110 368.3 0.0 3.1e-110 367.8 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EEQ30758.1 - 1.4e-29 102.0 0.9 2.9e-29 100.9 0.9 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FNIP_N PF14636.6 EEQ30759.1 - 1.1e-32 114.2 0.1 1.1e-32 114.2 0.1 4.6 4 0 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 EEQ30759.1 - 0.04 13.9 0.2 0.16 12.0 0.1 1.9 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain C9orf72-like PF15019.6 EEQ30759.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 C9orf72-like protein family SNF2_N PF00176.23 EEQ30761.1 - 3.1e-43 147.9 0.0 5e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ30761.1 - 9.3e-12 45.3 0.0 2.2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EEQ30761.1 - 0.0001 22.1 10.8 0.00026 20.8 10.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ30761.1 - 0.0059 16.5 11.3 0.015 15.3 11.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Phage-scaffold PF09306.10 EEQ30761.1 - 0.038 13.4 0.1 0.076 12.4 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein ERCC3_RAD25_C PF16203.5 EEQ30761.1 - 0.04 13.1 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_4 PF14447.6 EEQ30761.1 - 0.086 12.7 12.0 0.23 11.4 12.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EEQ30761.1 - 0.71 9.8 13.1 2.1 8.3 13.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EEQ30762.1 - 1.8e-09 37.0 25.9 3e-05 23.8 0.0 6.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ30762.1 - 1.2e-06 28.1 17.9 1.4e-05 24.7 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ30762.1 - 1.9e-06 27.6 7.3 0.037 14.3 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ30762.1 - 5.7e-06 26.9 20.3 0.00062 20.4 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ30762.1 - 6.5e-06 26.6 17.1 0.039 14.5 2.2 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ30762.1 - 9.7e-06 26.0 21.4 0.0039 17.9 0.3 7.5 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ30762.1 - 4.2e-05 23.7 17.0 0.12 12.7 3.4 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ30762.1 - 0.00016 21.3 10.6 0.00087 18.9 0.0 5.3 6 0 0 6 6 6 1 TPR repeat TPR_7 PF13176.6 EEQ30762.1 - 0.00023 20.9 7.2 0.28 11.3 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ30762.1 - 0.001 19.5 11.4 2.1 9.2 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ30762.1 - 0.01 15.7 7.9 12 5.9 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ30762.1 - 0.074 13.5 7.3 32 5.2 0.1 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat Put_DNA-bind_N PF06971.13 EEQ30762.1 - 0.2 11.7 0.0 0.48 10.5 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus TPR_9 PF13371.6 EEQ30762.1 - 0.58 10.4 0.0 0.58 10.4 0.0 5.1 7 0 0 7 7 6 0 Tetratricopeptide repeat Pmp3 PF01679.17 EEQ30763.1 - 5.1e-19 68.2 9.5 6.6e-19 67.9 9.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SH3_9 PF14604.6 EEQ30764.1 - 1.5e-06 28.0 1.4 1.8e-06 27.7 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EEQ30764.1 - 0.00028 20.4 0.1 0.00053 19.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Cytomega_TRL10 PF06084.11 EEQ30764.1 - 0.075 13.0 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein SKG6 PF08693.10 EEQ30764.1 - 0.45 10.0 2.9 0.82 9.1 2.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Fungal_trans PF04082.18 EEQ30768.1 - 5.5e-21 74.8 0.0 1.2e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ30768.1 - 5.2e-05 23.3 7.4 0.00012 22.2 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_Ca_ex PF01699.24 EEQ30769.1 - 1.2e-37 129.2 30.8 1e-19 71.0 16.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Bestrophin PF01062.21 EEQ30769.1 - 6.9 6.0 6.0 20 4.4 1.0 2.3 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel GHMP_kinases_N PF00288.26 EEQ30770.1 - 8.5e-16 58.0 0.9 2.3e-15 56.6 0.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEQ30770.1 - 7.1e-09 35.9 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal MCM PF00493.23 EEQ30771.1 - 2.3e-99 331.0 0.1 3.6e-99 330.4 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEQ30771.1 - 4e-38 130.1 0.4 8.3e-38 129.1 0.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EEQ30771.1 - 9.6e-33 112.6 2.2 2.4e-32 111.4 2.2 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EEQ30771.1 - 2e-24 85.8 0.4 7.3e-24 84.0 0.4 2.1 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ30771.1 - 2e-20 73.3 1.2 5.9e-20 71.8 0.3 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ30771.1 - 7.9e-05 22.1 0.0 0.0004 19.8 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ30771.1 - 0.0038 17.2 0.0 0.013 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEQ30771.1 - 0.0056 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEQ30771.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain GIDA_assoc PF13932.6 EEQ30771.1 - 0.053 13.7 3.2 0.11 12.6 3.2 1.6 1 0 0 1 1 1 0 GidA associated domain BUD22 PF09073.10 EEQ30771.1 - 5.3 6.3 6.4 7.9 5.7 6.4 1.2 1 0 0 1 1 1 0 BUD22 EamA PF00892.20 EEQ30772.1 - 1.2e-07 32.0 4.5 1.4e-07 31.8 4.5 1.1 1 0 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EEQ30772.1 - 0.093 12.8 3.4 0.12 12.4 3.4 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 Voltage_CLC PF00654.20 EEQ30773.1 - 1.5e-88 297.4 24.0 1.5e-88 297.4 24.0 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EEQ30773.1 - 1.9e-09 37.8 0.0 0.001 19.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain ATPase_gene1 PF09527.10 EEQ30773.1 - 4.6 7.5 13.0 6.7 7.0 1.5 3.8 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter CBFD_NFYB_HMF PF00808.23 EEQ30774.1 - 4.2e-12 46.2 0.0 8.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Rieske PF00355.26 EEQ30775.1 - 6e-11 42.1 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EEQ30775.1 - 0.00011 22.6 6.8 0.00028 21.3 0.7 3.0 2 1 1 3 3 3 1 Ubiquinol cytochrome reductase transmembrane region Bundlin PF05307.11 EEQ30775.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Bundlin FeoB_C PF07664.12 EEQ30775.1 - 0.1 12.3 0.1 9.5 6.0 0.0 3.0 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus She9_MDM33 PF05546.11 EEQ30776.1 - 4.2e-84 281.3 7.9 5.6e-84 280.9 7.9 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family MBD_C PF14048.6 EEQ30776.1 - 0.021 15.5 2.8 0.069 13.9 2.7 1.9 1 1 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF4407 PF14362.6 EEQ30776.1 - 0.049 13.0 3.4 0.076 12.4 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PsbH PF00737.20 EEQ30776.1 - 0.06 13.1 0.8 0.11 12.3 0.8 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein E2_bind PF08825.10 EEQ30776.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 E2 binding domain MetOD2 PF18548.1 EEQ30776.1 - 0.34 11.0 4.4 3.3 7.9 0.4 2.8 2 1 0 2 2 2 0 Metanogen output domain 2 DUF1110 PF06533.12 EEQ30776.1 - 1.1 9.2 7.2 38 4.2 3.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1110) TMF_DNA_bd PF12329.8 EEQ30776.1 - 3.9 7.6 8.1 3.5 7.7 0.8 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Aminotran_1_2 PF00155.21 EEQ30777.1 - 2.5e-33 115.7 0.0 3.9e-23 82.2 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EEQ30777.1 - 0.027 13.7 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Fungal_trans PF04082.18 EEQ30778.1 - 1.1e-09 37.8 0.6 2.1e-09 36.8 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ30778.1 - 1.4e-08 34.7 11.3 1.4e-08 34.7 11.3 3.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 EEQ30779.1 - 1.7e-75 253.9 0.0 3.6e-75 252.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EEQ30779.1 - 7.8e-49 166.6 0.6 2.2e-46 158.6 0.0 2.6 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EEQ30779.1 - 1.5e-36 126.6 0.0 4.9e-36 124.8 0.0 2.0 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ30779.1 - 1.2e-33 115.6 0.5 1.2e-33 115.6 0.5 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EEQ30779.1 - 7.7e-14 51.8 0.1 2e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EEQ30779.1 - 1.7e-12 47.8 0.1 8.6e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EEQ30779.1 - 8.5e-05 22.0 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Trp_DMAT PF11991.8 EEQ30780.1 - 5.6e-84 282.6 0.0 7e-84 282.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Orexin PF02072.15 EEQ30780.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Prepro-orexin DUF4060 PF13269.6 EEQ30780.1 - 0.053 13.6 0.2 11 6.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4060) FAD_binding_3 PF01494.19 EEQ30781.1 - 4.1e-14 52.6 2.5 7.7e-08 32.0 0.5 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EEQ30781.1 - 0.0015 18.2 0.8 0.027 14.0 0.1 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ30781.1 - 0.0027 17.9 0.0 0.0056 16.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DDE_Tnp_1_6 PF13751.6 EEQ30781.1 - 0.048 13.9 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Glyco_hydro_129 PF11308.8 EEQ30781.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 Thi4 PF01946.17 EEQ30781.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EEQ30781.1 - 0.12 11.6 0.3 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.27 EEQ30782.1 - 7.6e-14 52.2 2.5 6.5e-12 45.9 2.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 EEQ30782.1 - 0.00039 20.3 0.0 0.0023 17.9 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 EEQ30782.1 - 0.00044 19.8 0.0 0.00078 19.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Zn_clus PF00172.18 EEQ30783.1 - 8.4e-08 32.2 6.9 1.7e-07 31.3 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ30783.1 - 7.6e-07 28.4 0.0 1.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_75 PF07335.11 EEQ30784.1 - 2.9e-60 203.2 0.3 3.7e-60 202.9 0.3 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 PNP_phzG_C PF10590.9 EEQ30785.1 - 3e-20 72.0 5.2 4.2e-20 71.5 2.3 2.5 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EEQ30785.1 - 6.9e-11 42.2 0.0 5.1e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EEQ30785.1 - 0.023 15.3 0.0 0.09 13.4 0.0 1.9 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.6 EEQ30786.1 - 1.5e-40 137.1 12.7 1e-08 35.2 0.0 12.7 10 3 4 14 14 14 7 PPR repeat family PPR_3 PF13812.6 EEQ30786.1 - 5.6e-30 103.2 1.4 0.00061 19.8 0.0 10.7 9 3 4 13 13 13 7 Pentatricopeptide repeat domain PPR PF01535.20 EEQ30786.1 - 1.5e-25 87.6 12.8 0.0011 19.1 0.0 13.2 13 0 0 13 13 13 4 PPR repeat PPR_long PF17177.4 EEQ30786.1 - 2.2e-18 66.4 15.8 9.2e-09 35.0 0.1 6.0 6 1 0 6 6 6 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EEQ30786.1 - 2.7e-18 65.4 0.6 9.4e-06 25.2 0.1 9.4 11 0 0 11 11 11 3 PPR repeat RPM2 PF08579.11 EEQ30786.1 - 1.4e-06 28.7 0.1 0.00014 22.2 0.0 3.5 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 EEQ30786.1 - 0.028 13.5 0.6 2.5 7.2 0.0 3.6 4 0 0 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF2972 PF11186.8 EEQ30786.1 - 0.032 14.2 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) RecX PF02631.16 EEQ30786.1 - 0.044 14.2 0.7 20 5.7 0.5 3.2 3 0 0 3 3 3 0 RecX family Peptidase_S64 PF08192.11 EEQ30788.1 - 1.2e-08 34.0 0.0 2.4e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S64 Trypsin_2 PF13365.6 EEQ30788.1 - 0.013 16.4 0.0 0.23 12.4 0.0 2.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 EEQ30788.1 - 0.28 9.8 0.0 0.47 9.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase S46 Pkinase PF00069.25 EEQ30789.1 - 2e-23 83.1 0.0 1.7e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30789.1 - 1e-07 31.5 0.5 0.028 13.7 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 EEQ30789.1 - 0.015 14.7 0.1 0.025 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ30789.1 - 0.047 13.0 0.0 8.1 5.7 0.0 2.6 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 EEQ30789.1 - 0.14 12.1 1.3 0.21 11.5 0.2 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2252 PF10009.9 EEQ30789.1 - 0.18 10.8 0.2 0.29 10.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) F-box PF00646.33 EEQ30790.1 - 4.2e-05 23.3 0.4 0.00013 21.7 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EEQ30790.1 - 0.0004 20.2 0.3 0.001 18.9 0.0 1.8 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 EEQ30790.1 - 0.00043 20.1 0.1 0.0017 18.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like Peptidase_S41 PF03572.18 EEQ30791.1 - 4.8e-08 32.7 0.0 1.6e-07 31.0 0.0 1.8 2 1 0 2 2 2 1 Peptidase family S41 Ribosomal_L7Ae PF01248.26 EEQ30792.1 - 3.5e-25 87.6 0.0 4.1e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EEQ30792.1 - 0.00021 21.4 0.1 0.00025 21.1 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EEQ30792.1 - 0.0022 17.8 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RSN1_7TM PF02714.15 EEQ30793.1 - 1e-91 307.1 30.4 6e-91 304.6 18.6 3.2 4 0 0 4 4 4 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EEQ30793.1 - 1.9e-44 151.2 2.2 3.8e-44 150.2 0.7 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EEQ30793.1 - 1.3e-34 120.0 0.0 2.7e-34 118.9 0.0 1.5 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EEQ30793.1 - 4.6e-32 110.0 0.1 9.9e-32 109.0 0.1 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter EHN PF06441.12 EEQ30796.1 - 7.7e-37 126.0 0.9 1.9e-35 121.5 0.1 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EEQ30796.1 - 1.9e-15 57.2 0.1 4.7e-15 55.9 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ30796.1 - 3.6e-07 31.0 2.0 6.2e-07 30.2 2.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.7 EEQ30798.1 - 1.7e-36 124.7 5.4 8.1e-13 48.8 0.1 5.3 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ30798.1 - 8.9e-36 121.5 10.4 2.5e-10 40.4 0.1 6.7 3 3 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EEQ30798.1 - 1.9e-33 113.4 8.1 4.5e-05 23.7 0.0 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 EEQ30798.1 - 1.8e-32 107.7 6.2 1.6e-05 24.9 0.0 7.8 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 EEQ30798.1 - 4.6e-31 106.8 6.7 5.1e-08 33.3 0.4 7.5 4 3 4 8 8 8 7 Ankyrin repeats (many copies) DUF4665 PF15679.5 EEQ30800.1 - 0.081 13.6 1.5 0.5 11.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) zf-BED PF02892.15 EEQ30800.1 - 0.9 9.6 7.2 0.19 11.8 1.3 2.8 3 0 0 3 3 3 0 BED zinc finger Pyridox_oxase_2 PF12766.7 EEQ30801.1 - 6.1e-24 84.5 0.0 1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EEQ30801.1 - 0.025 14.6 0.5 0.065 13.3 0.5 1.8 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region LRR_9 PF14580.6 EEQ30802.1 - 4.3e-60 202.2 0.1 6.2e-60 201.7 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EEQ30802.1 - 4.4e-08 32.8 14.5 2.6e-05 23.9 4.0 2.8 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EEQ30802.1 - 3.2e-06 27.4 8.2 0.00036 20.8 1.6 3.6 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) HTH_38 PF13936.6 EEQ30802.1 - 0.04 13.7 0.2 0.1 12.4 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4349 PF14257.6 EEQ30802.1 - 0.072 12.5 1.3 0.12 11.8 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) T4_Gp59_C PF08994.10 EEQ30802.1 - 0.11 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term HTH_32 PF13565.6 EEQ30802.1 - 0.11 13.1 0.2 0.36 11.5 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain GDA1_CD39 PF01150.17 EEQ30803.1 - 9.9e-110 367.1 0.0 1.4e-109 366.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.21 EEQ30804.1 - 1.7e-17 63.3 0.0 3.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.15 EEQ30805.1 - 4.3e-92 308.1 0.0 4.9e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.29 EEQ30806.1 - 1.9e-39 135.3 0.0 2.9e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ30806.1 - 2.4e-20 72.9 0.0 1.3e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEQ30806.1 - 1.2e-18 67.1 0.0 2.5e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EEQ30806.1 - 2.3e-05 24.4 0.0 5.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EEQ30806.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Aminotran_MocR PF12897.7 EEQ30806.1 - 0.017 13.9 0.0 0.98 8.1 0.0 2.1 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase WD40 PF00400.32 EEQ30807.1 - 3.3e-12 46.7 8.0 0.0015 19.3 0.2 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ30807.1 - 0.001 19.3 0.2 6.7 7.1 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ParD_like PF11903.8 EEQ30807.1 - 0.06 13.4 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system Fungal_trans_2 PF11951.8 EEQ30808.1 - 3.2e-09 36.1 3.0 2e-07 30.1 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF305 PF03713.13 EEQ30808.1 - 2 8.5 14.8 2.4 8.3 7.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF305) MFS_1 PF07690.16 EEQ30809.1 - 4.2e-43 147.6 43.0 4.2e-43 147.6 43.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ30809.1 - 2.9e-06 26.0 15.8 4.2e-06 25.5 15.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.28 EEQ30810.1 - 1.1e-09 38.4 0.0 1.4e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EEQ30810.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF775 PF05603.12 EEQ30811.1 - 2.6e-69 232.7 0.1 3e-69 232.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.28 EEQ30812.1 - 1.9e-11 44.1 0.0 3.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EEQ30812.1 - 4.6e-11 42.8 0.0 6.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) RNA_pol_Rpb8 PF03870.15 EEQ30813.1 - 1.9e-46 157.7 0.0 2.2e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.11 EEQ30814.1 - 1.3e-118 396.4 0.0 1.5e-118 396.2 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 EEQ30815.1 - 1.3e-14 54.0 0.0 4.1e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain Casc1 PF12366.8 EEQ30815.1 - 0.82 9.1 3.7 1.2 8.6 3.7 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 UPF0086 PF01868.16 EEQ30816.1 - 4.4e-30 103.4 0.0 7.6e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 EFP PF01132.20 EEQ30817.1 - 0.22 11.6 1.8 29 4.8 0.0 3.5 4 0 0 4 4 4 0 Elongation factor P (EF-P) OB domain SARG PF15385.6 EEQ30817.1 - 9.4 5.3 15.3 0.089 12.0 4.1 2.1 2 0 0 2 2 2 0 Specifically androgen-regulated gene protein Copper-bind PF00127.20 EEQ30818.1 - 0.0018 18.7 0.2 0.0043 17.5 0.2 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EEQ30818.1 - 0.035 14.2 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Cupredoxin-like domain DUF908 PF06012.12 EEQ30818.1 - 0.54 9.6 2.5 0.68 9.3 2.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4512 PF14975.6 EEQ30818.1 - 9.8 7.0 7.3 1.9 9.3 3.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) Ank_2 PF12796.7 EEQ30819.1 - 2.3e-68 226.8 12.3 1.4e-14 54.5 0.1 6.1 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ30819.1 - 5.7e-38 128.5 8.3 9.3e-09 35.4 0.0 7.7 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ30819.1 - 7.9e-38 128.4 9.3 7.6e-08 32.8 0.0 8.5 3 3 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ30819.1 - 1.2e-33 111.3 1.9 0.0011 19.3 0.0 10.4 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 EEQ30819.1 - 2.3e-31 106.8 5.6 0.0059 17.0 0.0 10.8 11 0 0 11 11 11 8 Ankyrin repeat Trehalase_Ca-bi PF07492.11 EEQ30819.1 - 0.033 13.9 1.2 26 4.7 0.1 4.1 5 0 0 5 5 5 0 Neutral trehalase Ca2+ binding domain MFS_1 PF07690.16 EEQ30820.1 - 1.2e-24 86.9 23.7 1.2e-24 86.9 23.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phos_pyr_kin PF08543.12 EEQ30820.1 - 0.033 13.6 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Peptidase_U4 PF03419.13 EEQ30820.1 - 0.49 9.6 19.2 0.082 12.2 12.2 2.4 2 0 0 2 2 2 0 Sporulation factor SpoIIGA PRIMA1 PF16101.5 EEQ30820.1 - 0.85 9.7 2.4 26 4.9 0.1 2.7 2 1 1 3 3 3 0 Proline-rich membrane anchor 1 Zn_ribbon_17 PF17120.5 EEQ30822.1 - 0.0019 17.8 4.3 0.0019 17.8 4.3 3.2 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EEQ30822.1 - 0.0032 17.3 37.3 0.21 11.4 6.5 3.3 3 0 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ30822.1 - 0.0086 15.9 38.3 0.27 11.1 6.6 3.4 3 0 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 EEQ30822.1 - 0.012 15.8 22.5 0.46 10.7 2.5 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger zf-RING_2 PF13639.6 EEQ30822.1 - 1 9.8 36.6 1.7 9.0 6.4 3.3 3 0 0 3 3 3 0 Ring finger domain zf-RING_UBOX PF13445.6 EEQ30822.1 - 2.5 8.2 30.5 0.94 9.6 5.1 3.6 3 0 0 3 3 3 0 RING-type zinc-finger Ank_2 PF12796.7 EEQ30823.1 - 2.2e-38 130.7 7.6 1.2e-12 48.2 0.2 4.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ30823.1 - 2.9e-35 120.2 3.2 5.8e-11 42.7 0.1 6.6 3 3 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ30823.1 - 9.9e-27 90.1 6.5 2.7e-06 27.3 0.0 8.1 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 EEQ30823.1 - 7.8e-24 83.0 6.7 1.7e-05 25.0 0.0 7.4 7 1 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EEQ30823.1 - 1.9e-19 69.4 5.9 8.1e-08 32.4 0.0 6.8 2 2 5 7 7 7 5 Ankyrin repeats (many copies) NACHT PF05729.12 EEQ30824.1 - 8.6e-11 42.0 0.1 2e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 EEQ30824.1 - 2e-09 37.5 0.1 0.00013 22.2 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ30824.1 - 3e-09 37.3 0.0 1.9e-08 34.7 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ30824.1 - 6.4e-07 29.8 0.0 9e-06 26.1 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ30824.1 - 7.6e-06 25.9 0.0 0.12 13.0 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EEQ30824.1 - 5.3e-05 23.5 0.3 0.013 15.9 0.5 3.4 3 0 0 3 3 3 1 Ankyrin repeat KAP_NTPase PF07693.14 EEQ30824.1 - 0.003 16.9 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Mg_chelatase PF01078.21 EEQ30824.1 - 0.0082 15.5 0.0 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EEQ30824.1 - 0.029 14.7 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EEQ30824.1 - 0.035 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EEQ30824.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein HlyIII PF03006.20 EEQ30825.1 - 4.3e-47 160.7 15.1 5.4e-47 160.4 15.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_S8 PF00082.22 EEQ30826.1 - 8.4e-15 54.8 0.0 1.9e-14 53.6 0.0 1.5 1 1 0 1 1 1 1 Subtilase family Cofilin_ADF PF00241.20 EEQ30828.1 - 4.4e-16 58.8 0.1 5.9e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein stn_TNFRSF12A PF12191.8 EEQ30828.1 - 0.079 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MoCF_biosynth PF00994.24 EEQ30829.1 - 6.2e-31 107.0 0.0 1.1e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.22 EEQ30830.1 - 5.6e-60 201.6 0.2 6.6e-60 201.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ30830.1 - 2.7e-20 72.8 0.0 4.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ30830.1 - 1.8e-07 30.8 0.0 2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ30830.1 - 2.1e-05 24.2 0.1 0.0002 21.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ30830.1 - 5.2e-05 23.2 0.5 0.22 11.4 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EEQ30830.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EEQ30830.1 - 0.0028 17.7 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EEQ30830.1 - 0.0033 17.4 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain DUF2075 PF09848.9 EEQ30830.1 - 0.18 11.0 0.4 10 5.2 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 EEQ30830.1 - 0.29 10.9 0.9 3.3 7.4 0.2 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein IHABP4_N PF16174.5 EEQ30831.1 - 0.52 10.9 7.4 0.62 10.6 7.4 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal adh_short PF00106.25 EEQ30832.1 - 7e-54 182.3 0.0 9.4e-54 181.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ30832.1 - 9.8e-36 123.5 0.0 1.3e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ30832.1 - 1.4e-12 47.9 0.0 2.1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EEQ30832.1 - 0.004 16.3 0.1 0.01 15.0 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EEQ30832.1 - 0.024 14.9 0.1 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Eno-Rase_NADH_b PF12242.8 EEQ30832.1 - 0.042 13.6 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.21 EEQ30832.1 - 0.12 11.7 0.1 0.69 9.2 0.0 1.9 2 0 0 2 2 2 0 ThiF family GATA PF00320.27 EEQ30835.1 - 8.4e-29 98.9 17.4 2.4e-15 55.8 4.8 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 EEQ30835.1 - 5.7e-08 32.1 3.8 0.0016 17.9 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Auto_anti-p27 PF06677.12 EEQ30835.1 - 0.0032 17.6 6.4 0.28 11.3 0.9 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 EEQ30835.1 - 0.017 15.2 8.8 0.081 13.1 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain Roughex PF06020.11 EEQ30835.1 - 0.031 13.4 1.8 0.062 12.4 1.8 1.5 1 0 0 1 1 1 0 Drosophila roughex protein ArfGap PF01412.18 EEQ30835.1 - 0.11 12.5 11.4 1.1 9.4 0.1 3.2 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf DZR PF12773.7 EEQ30835.1 - 0.14 12.2 14.3 0.79 9.8 1.0 3.3 2 2 1 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 EEQ30835.1 - 3.6 7.5 5.2 24 4.8 0.7 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 EEQ30835.1 - 6.5 6.8 14.6 0.88 9.5 0.4 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain COPI_assoc PF08507.10 EEQ30836.1 - 4.8e-31 107.5 7.1 5.7e-31 107.3 7.1 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2371 PF10177.9 EEQ30836.1 - 2.5 8.3 6.8 3.6 7.7 0.5 2.3 1 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DAO PF01266.24 EEQ30837.1 - 8.1e-34 117.7 0.3 9.4e-34 117.5 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ30837.1 - 0.00093 19.4 0.1 0.0023 18.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ30837.1 - 0.0068 16.9 0.1 0.019 15.5 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EEQ30837.1 - 0.019 15.4 0.0 0.043 14.3 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 EEQ30837.1 - 0.019 14.2 0.3 0.069 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EEQ30837.1 - 0.02 15.1 0.1 0.058 13.7 0.1 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1188 PF06690.11 EEQ30837.1 - 0.05 13.1 0.1 7.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Thi4 PF01946.17 EEQ30837.1 - 0.083 12.1 0.1 0.083 12.1 0.1 1.6 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 EEQ30837.1 - 0.12 12.0 0.3 1.3 8.7 0.2 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA p450 PF00067.22 EEQ30838.1 - 2.7e-31 108.9 0.0 2.5e-30 105.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Amidinotransf PF02274.17 EEQ30839.1 - 2e-11 43.6 0.0 5.8e-05 22.4 0.0 2.6 3 0 0 3 3 3 2 Amidinotransferase PSDC PF12588.8 EEQ30840.1 - 9.6e-35 119.6 0.0 5.6e-17 62.0 0.0 2.3 1 1 1 2 2 2 2 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EEQ30840.1 - 5.8e-21 75.0 0.0 9.3e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase TauD PF02668.16 EEQ30841.1 - 2.5e-14 53.7 0.1 2e-12 47.5 0.1 2.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EEQ30841.1 - 0.037 13.1 0.0 0.063 12.4 0.0 1.6 1 1 0 1 1 1 0 CsiD ATPgrasp_ST PF14397.6 EEQ30842.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Glyco_transf_54 PF04666.13 EEQ30844.1 - 1.1e-07 31.1 0.0 0.0004 19.3 0.0 3.0 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.17 EEQ30844.1 - 0.0069 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Type_ISP_C PF18135.1 EEQ30844.1 - 0.015 14.3 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Type ISP C-terminal specificity domain CUE PF02845.16 EEQ30845.1 - 4.7e-06 26.2 0.1 8.5e-05 22.2 0.0 2.5 2 0 0 2 2 2 1 CUE domain Thioredoxin PF00085.20 EEQ30846.1 - 2.8e-29 101.1 0.1 3e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EEQ30846.1 - 2.5e-07 30.9 0.0 2.7e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EEQ30846.1 - 1.9e-06 28.3 0.2 1.4e-05 25.5 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EEQ30846.1 - 0.00011 22.0 0.0 0.00012 21.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EEQ30846.1 - 0.00032 20.4 0.1 0.0022 17.7 0.1 1.9 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 EEQ30846.1 - 0.00048 20.0 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EEQ30846.1 - 0.003 17.7 0.0 0.0043 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 EEQ30846.1 - 0.0053 16.7 0.0 0.0072 16.3 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 EEQ30846.1 - 0.0068 16.3 0.0 0.008 16.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 EEQ30846.1 - 0.015 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 EEQ30846.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 EEQ30846.1 - 0.041 14.1 0.1 0.062 13.5 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin DUF1681 PF07933.14 EEQ30848.1 - 1.1e-54 184.2 0.0 1.4e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) IF-2B PF01008.17 EEQ30849.1 - 1.3e-49 168.9 0.0 2e-49 168.3 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family Nuf2 PF03800.14 EEQ30850.1 - 1.4e-40 138.6 0.1 4.2e-40 137.1 0.1 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EEQ30850.1 - 1.6e-29 102.3 15.9 1.6e-29 102.3 15.9 4.2 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain ATG16 PF08614.11 EEQ30850.1 - 0.91 9.7 54.7 0.28 11.4 10.4 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EEQ30850.1 - 2.3 7.0 52.7 2.9 6.7 13.6 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein VSG_B PF13206.6 EEQ30850.1 - 5.7 6.1 30.3 2.9 7.1 0.0 3.1 1 1 2 3 3 3 0 Trypanosomal VSG domain WPP PF13943.6 EEQ30851.1 - 0.045 14.1 0.1 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 WPP domain Adaptin_N PF01602.20 EEQ30852.1 - 2.7e-95 319.9 0.0 3.3e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EEQ30852.1 - 3.3e-16 59.7 0.0 2.3e-14 53.8 0.0 3.3 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ30852.1 - 3.8e-10 40.0 0.8 0.0007 19.9 0.0 4.6 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.22 EEQ30852.1 - 1e-06 28.5 1.4 0.12 12.7 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat SPO22 PF08631.10 EEQ30852.1 - 0.0039 16.7 0.2 0.38 10.2 0.1 2.7 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like Cohesin_HEAT PF12765.7 EEQ30852.1 - 0.023 15.0 0.1 1.1 9.7 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion VHS PF00790.19 EEQ30852.1 - 0.082 12.8 0.8 51 3.7 0.0 3.9 5 0 0 5 5 5 0 VHS domain Arm PF00514.23 EEQ30852.1 - 0.59 10.3 4.4 4.6 7.4 0.1 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CobT PF06213.12 EEQ30852.1 - 0.89 8.9 19.7 0.49 9.7 17.5 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT zf-CCHC PF00098.23 EEQ30853.1 - 0.0047 16.9 2.4 0.0076 16.3 2.4 1.3 1 0 0 1 1 1 1 Zinc knuckle SseC PF04888.12 EEQ30853.1 - 0.0053 16.4 0.1 0.0083 15.8 0.1 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family DUF445 PF04286.12 EEQ30853.1 - 0.032 14.0 1.5 0.042 13.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2336 PF10098.9 EEQ30853.1 - 0.036 13.5 3.6 0.053 13.0 3.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) YtxH PF12732.7 EEQ30853.1 - 0.38 11.3 9.1 1.3 9.6 9.1 1.9 1 1 0 1 1 1 0 YtxH-like protein REF PF05755.12 EEQ30853.1 - 0.93 9.3 6.0 1.6 8.5 6.0 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Mor PF08765.11 EEQ30853.1 - 1 9.4 2.7 2.4 8.2 1.8 1.9 1 1 1 2 2 2 0 Mor transcription activator family pP_pnuc_2 PF18166.1 EEQ30853.1 - 4.6 7.3 10.3 14 5.8 3.8 2.3 1 1 1 2 2 2 0 Predicted pPIWI-associating nuclease zf-CCHC_6 PF15288.6 EEQ30853.1 - 5 7.1 5.9 2.5 8.0 2.9 2.1 2 0 0 2 2 2 0 Zinc knuckle CBFD_NFYB_HMF PF00808.23 EEQ30853.1 - 5 7.5 13.0 11 6.3 9.0 2.4 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Metallophos PF00149.28 EEQ30854.1 - 7.7e-37 127.8 0.3 1.1e-36 127.3 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEQ30854.1 - 0.063 13.7 0.3 0.18 12.2 0.3 1.9 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Rho_GDI PF02115.17 EEQ30855.1 - 4.7e-65 219.0 0.1 5.1e-65 218.9 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor GFA PF04828.14 EEQ30856.1 - 5.9e-05 23.3 2.2 5.9e-05 23.3 2.2 2.2 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.13 EEQ30856.1 - 0.00067 19.3 0.7 0.00067 19.3 0.7 1.9 2 0 0 2 2 2 1 CSL zinc finger Nudix_N_2 PF14803.6 EEQ30856.1 - 0.0038 17.1 0.1 0.0038 17.1 0.1 2.5 2 1 0 2 2 2 1 Nudix N-terminal zf-NADH-PPase PF09297.11 EEQ30856.1 - 0.0046 16.6 0.6 0.0046 16.6 0.6 2.3 2 1 1 3 3 3 1 NADH pyrophosphatase zinc ribbon domain PAXX PF15384.6 EEQ30857.1 - 0.014 15.1 0.8 0.038 13.7 0.8 1.7 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 KilA-N PF04383.13 EEQ30857.1 - 0.033 14.0 0.2 2.2 8.2 0.0 2.9 2 1 1 3 3 3 0 KilA-N domain CLP1_P PF16575.5 EEQ30858.1 - 2.8e-33 115.3 0.0 2.1e-32 112.4 0.0 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EEQ30858.1 - 1.2e-26 92.8 0.0 2.4e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EEQ30858.1 - 1.3e-24 86.8 0.0 3.2e-24 85.6 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 EEQ30858.1 - 0.00019 21.3 0.0 0.0034 17.2 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EEQ30858.1 - 0.0024 17.9 0.1 0.022 14.8 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EEQ30858.1 - 0.019 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EEQ30858.1 - 0.071 12.5 0.1 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EEQ30858.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_35 PF14516.6 EEQ30858.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Pet100 PF09803.9 EEQ30859.1 - 0.21 12.1 0.4 0.6 10.7 0.4 1.7 1 0 0 1 1 1 0 Pet100 Sgf11 PF08209.11 EEQ30859.1 - 1.6 8.4 6.6 0.14 11.7 0.2 2.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) ADH_zinc_N PF00107.26 EEQ30860.1 - 4.2e-27 94.7 0.0 7.4e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ30860.1 - 3.3e-22 80.0 0.0 5.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ30860.1 - 1.5e-07 31.2 0.0 5.2e-07 29.5 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EEQ30860.1 - 0.0051 16.7 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 EEQ30860.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain LpxK PF02606.14 EEQ30861.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Fringe PF02434.16 EEQ30862.1 - 2.8e-06 26.9 0.5 8.8e-05 22.1 0.1 2.5 2 1 0 2 2 2 1 Fringe-like PAN_1 PF00024.26 EEQ30862.1 - 0.0012 18.8 1.0 0.0021 18.0 1.0 1.3 1 0 0 1 1 1 1 PAN domain Glyco_trans_2_3 PF13632.6 EEQ30862.1 - 0.04 13.8 0.6 2.2 8.2 0.1 2.3 1 1 1 2 2 2 0 Glycosyl transferase family group 2 Galactosyl_T PF01762.21 EEQ30862.1 - 0.09 12.6 0.0 1.8 8.4 0.0 2.2 1 1 1 2 2 2 0 Galactosyltransferase PAN_4 PF14295.6 EEQ30862.1 - 0.11 12.4 1.6 0.22 11.5 1.6 1.4 1 0 0 1 1 1 0 PAN domain Arb1 PF09692.10 EEQ30863.1 - 1.5e-126 422.9 1.5 1.2e-124 416.5 1.5 2.1 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.16 EEQ30864.1 - 5.6e-60 202.6 0.0 7e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_S19 PF00203.21 EEQ30865.1 - 3.9e-24 84.3 0.0 4.6e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 EEQ30866.1 - 3.5e-22 78.1 0.1 5.9e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TRF PF08558.10 EEQ30868.1 - 8.9e-80 267.7 0.1 1.6e-79 266.9 0.1 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EEQ30868.1 - 0.00053 20.1 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4578 PF15147.6 EEQ30868.1 - 1.6 9.6 4.9 2.7 8.9 1.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4578) His_Phos_2 PF00328.22 EEQ30869.1 - 1.5e-07 31.1 0.0 7.2e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 EEQ30871.1 - 8.1e-30 103.9 46.5 3.9e-26 91.8 49.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily UL41A PF17591.2 EEQ30871.1 - 0.0044 17.1 0.9 0.0044 17.1 0.9 2.8 3 0 0 3 3 3 1 Herpesvirus UL41A Pox_A14 PF05767.12 EEQ30871.1 - 0.031 14.4 0.2 0.031 14.4 0.2 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF4006 PF13179.6 EEQ30871.1 - 0.37 10.7 0.1 0.37 10.7 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF4006) DUF4267 PF14087.6 EEQ30872.1 - 2.9e-26 91.7 6.9 3.5e-26 91.5 6.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4345 PF14248.6 EEQ30872.1 - 0.009 15.9 10.7 0.012 15.5 10.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) DUF2157 PF09925.9 EEQ30872.1 - 2.2 8.0 8.2 1.7 8.4 4.3 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2892 PF11127.8 EEQ30872.1 - 6.8 6.8 10.2 1.9 8.6 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) Pkinase PF00069.25 EEQ30873.1 - 6.2e-75 252.0 0.0 8.8e-75 251.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30873.1 - 1.8e-31 109.4 0.0 1.9e-22 79.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEQ30873.1 - 2.8e-06 26.9 0.1 0.72 9.1 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EEQ30873.1 - 0.022 13.6 0.6 0.039 12.7 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EEQ30873.1 - 0.034 13.5 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ30873.1 - 0.17 11.8 0.0 3.6 7.4 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.10 EEQ30874.1 - 3.7e-29 100.6 2.0 6.4e-29 99.8 2.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.15 EEQ30875.1 - 5.2e-22 77.1 0.0 1.1e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EEQ30875.1 - 2.8e-19 68.8 0.2 5.5e-19 67.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain APH PF01636.23 EEQ30877.1 - 1.9e-09 37.8 0.0 5.6e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ30877.1 - 7e-05 22.5 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ30877.1 - 0.0049 16.3 0.0 0.029 13.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain CRAL_TRIO PF00650.20 EEQ30877.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO domain COX2-transmemb PF09125.10 EEQ30878.1 - 0.098 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane APH PF01636.23 EEQ30879.1 - 8.4e-13 48.8 0.0 1.3e-11 44.9 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.7 EEQ30880.1 - 2e-78 259.0 8.8 5.8e-12 46.0 0.0 11.8 4 2 7 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ30880.1 - 1.3e-71 236.1 22.7 4.6e-08 33.5 0.1 16.0 8 4 7 16 16 16 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ30880.1 - 1.3e-50 168.8 14.6 1.1e-07 32.0 0.1 15.0 14 2 2 16 16 16 11 Ankyrin repeats (many copies) Ank PF00023.30 EEQ30880.1 - 1.7e-46 154.7 22.2 7.5e-05 23.0 0.2 17.4 16 2 1 17 17 17 11 Ankyrin repeat Ank_3 PF13606.6 EEQ30880.1 - 3.4e-44 143.7 22.5 0.003 17.9 0.0 18.9 19 0 0 19 19 19 9 Ankyrin repeat DUF3447 PF11929.8 EEQ30880.1 - 0.00019 21.3 0.0 0.059 13.3 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) F-box_4 PF15966.5 EEQ30880.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box tRNA_U5-meth_tr PF05958.11 EEQ30881.1 - 4.2e-17 62.2 0.1 7.2e-15 54.8 0.0 3.1 2 2 1 3 3 3 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EEQ30881.1 - 2.5e-05 24.1 0.0 5.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ30881.1 - 9.1e-05 23.1 0.0 0.00022 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EEQ30881.1 - 0.0004 20.0 0.0 0.00085 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 EEQ30881.1 - 0.003 18.2 0.0 0.0086 16.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEQ30881.1 - 0.018 14.4 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Actin PF00022.19 EEQ30882.1 - 1.1e-87 294.4 0.0 1.1e-85 287.8 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEQ30882.1 - 0.00015 20.8 0.1 0.0046 15.8 0.1 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EEQ30882.1 - 0.0052 17.2 0.0 0.0077 16.6 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsA Asparaginase_2 PF01112.18 EEQ30883.1 - 1.4e-45 155.6 1.8 8.6e-29 100.5 0.0 2.1 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.14 EEQ30884.1 - 1.5e-111 372.3 0.0 2e-111 372.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 UNC45-central PF11701.8 EEQ30885.1 - 1.3e-41 142.2 1.0 4.4e-41 140.4 0.1 2.5 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 EEQ30885.1 - 0.0006 20.2 6.1 14 6.2 0.0 5.5 3 1 2 5 5 5 3 HEAT repeats Atx10homo_assoc PF09759.9 EEQ30885.1 - 0.085 12.9 0.0 10 6.2 0.0 2.9 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EEQ30885.1 - 0.18 11.9 8.4 20 5.4 0.1 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Stig1 PF04885.13 EEQ30886.1 - 0.00059 20.3 72.9 0.14 12.6 27.6 3.5 1 1 2 3 3 3 2 Stigma-specific protein, Stig1 LRRNT PF01462.18 EEQ30886.1 - 0.73 9.6 11.4 1.1 8.9 0.3 3.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain APH PF01636.23 EEQ30887.1 - 3.9e-09 36.8 0.2 1.2e-08 35.2 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family GDPD PF03009.17 EEQ30888.1 - 2.5e-56 191.3 0.0 4.6e-56 190.4 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EEQ30888.1 - 8.5e-25 87.2 0.6 2.4e-07 31.3 0.6 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.19 EEQ30888.1 - 3.5e-23 83.1 7.8 2.7e-12 47.3 0.1 4.0 2 1 2 4 4 4 3 SPX domain Ank_4 PF13637.6 EEQ30888.1 - 4.8e-23 81.2 1.4 2.4e-08 34.4 0.1 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EEQ30888.1 - 1.8e-18 66.1 1.3 0.0007 19.9 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EEQ30888.1 - 4.7e-16 58.7 0.4 0.00029 21.1 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ30888.1 - 8.3e-15 53.4 0.5 0.017 15.6 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat TAT_signal PF10518.9 EEQ30888.1 - 0.037 13.9 0.1 0.84 9.6 0.1 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PRMT5_TIM PF17285.2 EEQ30889.1 - 1.9e-69 233.7 0.0 3.1e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 EEQ30889.1 - 6.8e-66 221.4 0.0 1.1e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EEQ30889.1 - 9.1e-58 195.0 0.1 1.9e-57 194.0 0.1 1.6 1 0 0 1 1 1 1 PRMT5 oligomerisation domain OB_NTP_bind PF07717.16 EEQ30890.1 - 8.6e-20 70.9 0.0 2.3e-19 69.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EEQ30890.1 - 9.2e-19 67.7 0.0 2.5e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ30890.1 - 2.7e-10 40.6 0.0 8.9e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ30890.1 - 4.3e-07 29.9 0.1 7.6e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEQ30890.1 - 4.6e-05 23.7 0.2 0.00016 22.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EEQ30890.1 - 0.00038 20.1 0.1 0.0011 18.6 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EEQ30890.1 - 0.002 18.5 0.1 0.0041 17.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EEQ30890.1 - 0.0033 17.4 0.1 0.0062 16.5 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 EEQ30890.1 - 0.0052 16.5 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EEQ30890.1 - 0.041 13.9 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Forkhead PF00250.18 EEQ30890.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Forkhead domain AAA_23 PF13476.6 EEQ30890.1 - 0.062 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EEQ30890.1 - 0.095 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NPV_P10 PF05531.12 EEQ30891.1 - 0.14 12.6 2.6 7.2 7.2 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SLATT_fungal PF18142.1 EEQ30891.1 - 4.3 7.3 5.7 0.69 9.9 0.2 2.5 3 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain EF-hand_6 PF13405.6 EEQ30892.1 - 4.6e-09 35.5 1.0 0.00018 21.2 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EEQ30892.1 - 4.1e-05 24.0 1.4 0.00013 22.4 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EEQ30892.1 - 0.0098 15.4 0.0 0.69 9.6 0.0 2.5 2 0 0 2 2 2 1 EF hand Skp1 PF01466.19 EEQ30892.1 - 3.2 7.9 4.4 41 4.4 0.4 2.8 2 1 1 3 3 3 0 Skp1 family, dimerisation domain Met_10 PF02475.16 EEQ30893.1 - 0.0002 21.2 0.0 0.00056 19.7 0.0 1.7 1 1 0 1 1 1 1 Met-10+ like-protein GvpO PF05800.11 EEQ30893.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO CBM_20 PF00686.19 EEQ30895.1 - 0.14 12.1 0.2 0.21 11.5 0.2 1.2 1 0 0 1 1 1 0 Starch binding domain MFS_1 PF07690.16 EEQ30896.1 - 9.6e-26 90.5 68.8 4.5e-23 81.7 39.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_1 PF00515.28 EEQ30897.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.32 EEQ30898.1 - 1.4e-05 25.7 0.1 0.023 15.6 0.0 4.7 4 1 1 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ30898.1 - 0.00011 22.5 0.0 0.47 10.8 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EEQ30898.1 - 0.0022 17.1 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 1 Coatomer WD associated region Hira PF07569.11 EEQ30898.1 - 0.023 14.4 0.2 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split CNH PF00780.22 EEQ30898.1 - 0.039 13.6 0.1 2.8 7.5 0.0 2.8 2 1 0 2 2 2 0 CNH domain Ge1_WD40 PF16529.5 EEQ30898.1 - 0.12 11.3 0.0 0.35 9.8 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Actino_peptide PF14408.6 EEQ30898.1 - 0.4 10.8 4.0 0.45 10.6 2.1 2.0 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes LCM PF04072.14 EEQ30899.1 - 6e-18 65.5 0.0 9.3e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EEQ30899.1 - 3.4e-15 55.8 17.2 1.9e-09 37.4 0.1 6.2 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EEQ30899.1 - 0.00049 20.3 9.9 0.7 10.3 0.1 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EEQ30899.1 - 0.0051 16.7 3.9 20 5.4 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 EEQ30899.1 - 0.042 13.4 2.5 2.4 7.8 0.1 4.3 5 0 0 5 5 5 0 Kelch motif OrfB_IS605 PF01385.19 EEQ30899.1 - 0.18 12.0 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 Probable transposase ADH_zinc_N PF00107.26 EEQ30900.1 - 7.1e-15 55.1 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ30900.1 - 0.0013 19.8 0.0 0.0027 18.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MSV199 PF10553.9 EEQ30900.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 MSV199 domain DSPc PF00782.20 EEQ30901.1 - 7e-26 90.6 0.0 1.3e-18 67.1 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEQ30901.1 - 0.0038 16.8 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Mlh1_C PF16413.5 EEQ30903.1 - 1.3e-104 349.4 0.0 1.8e-104 348.9 0.0 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EEQ30903.1 - 2.1e-31 108.0 0.0 5.7e-31 106.7 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EEQ30903.1 - 0.00034 20.5 0.6 0.059 13.2 0.0 2.7 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase APH PF01636.23 EEQ30904.1 - 2.2e-06 27.8 0.0 0.00082 19.4 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ30904.1 - 0.0016 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EEQ30904.1 - 0.028 14.0 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 RIO1 family RPN1_RPN2_N PF17781.1 EEQ30908.1 - 5.5e-92 308.5 1.0 2.1e-73 247.4 0.1 2.5 1 1 1 2 2 2 2 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EEQ30908.1 - 4.1e-29 100.4 0.0 7.6e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EEQ30908.1 - 1.5e-19 69.3 14.5 6.9e-05 23.1 0.1 8.4 8 1 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EEQ30908.1 - 0.0018 18.6 1.3 3.1 8.3 0.0 4.0 4 1 1 5 5 5 3 HEAT repeats IFRD PF05004.13 EEQ30908.1 - 2 7.4 4.8 1.7 7.7 0.6 2.8 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Cyclin PF08613.11 EEQ30911.1 - 3.1e-13 50.4 0.0 6.5e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EEQ30911.1 - 0.0061 16.3 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.14 EEQ30913.1 - 6.5e-47 160.2 0.1 8.1e-47 159.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ30913.1 - 1e-10 42.0 0.0 1.8e-09 38.0 0.0 2.7 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ30913.1 - 0.0033 16.7 0.6 3.9 6.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_oprn_chp PF09534.10 EEQ30914.1 - 0.029 14.2 0.1 0.045 13.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Acetyltransf_1 PF00583.25 EEQ30915.1 - 6.4e-10 39.3 0.0 1.1e-09 38.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ30915.1 - 1.1e-09 38.6 0.1 2e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ30915.1 - 1.6e-09 37.8 0.0 2.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEQ30915.1 - 1.7e-06 28.1 0.0 0.0032 17.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ30915.1 - 4.2e-05 23.4 0.0 0.00012 22.0 0.0 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 EEQ30915.1 - 0.0002 21.4 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Arrestin_C PF02752.22 EEQ30916.1 - 7.7e-15 55.5 0.0 3.4e-14 53.4 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EEQ30916.1 - 9.5e-08 32.2 0.0 0.0021 18.1 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain T3SS_NleG PF06416.12 EEQ30916.1 - 0.11 12.4 0.2 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 Effector protein NleG RRM_1 PF00076.22 EEQ30918.1 - 1.2e-59 198.1 0.0 3.8e-21 74.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ30918.1 - 1.6e-08 34.2 0.0 0.0002 20.9 0.0 3.1 2 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ30918.1 - 6.6e-08 32.3 0.0 0.0089 15.9 0.0 3.5 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EEQ30918.1 - 3e-05 23.9 0.1 3.6 7.7 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 EEQ30918.1 - 0.001 19.2 0.0 0.71 10.1 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain Cas_Cas2CT1978 PF09707.10 EEQ30918.1 - 0.0019 18.3 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM PF05172.13 EEQ30918.1 - 0.0027 17.6 0.0 11 6.0 0.0 3.3 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EEQ30918.1 - 0.011 15.8 0.0 11 6.2 0.0 3.4 3 0 0 3 3 3 0 RNA recognition motif SET_assoc PF11767.8 EEQ30918.1 - 0.066 12.9 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated PIG-Y PF15159.6 EEQ30919.1 - 2.6e-23 82.7 8.6 4.2e-23 82.1 8.6 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Myb_Cef PF11831.8 EEQ30919.1 - 0.03 13.9 0.4 0.059 12.9 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA splicing factor component DUF1218 PF06749.12 EEQ30919.1 - 0.43 11.1 4.9 3.7 8.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2956 PF11169.8 EEQ30919.1 - 1.2 9.4 5.6 0.49 10.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) GATase_4 PF13230.6 EEQ30920.1 - 3.6e-13 49.1 0.0 2.1e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EEQ30920.1 - 4.6e-07 30.1 0.0 8.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Kazal_2 PF07648.15 EEQ30921.1 - 3e-06 27.3 1.6 4.1e-06 26.8 1.6 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 EEQ30921.1 - 2.3e-05 24.3 0.9 3.1e-05 23.9 0.9 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Dynamin_N PF00350.23 EEQ30922.1 - 6.1e-44 150.0 0.0 1.3e-43 148.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EEQ30922.1 - 3.2e-13 49.6 0.0 8.9e-11 41.5 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EEQ30922.1 - 2.2e-05 24.5 0.0 5.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ30922.1 - 0.0045 17.4 1.0 0.054 13.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_15 PF13175.6 EEQ30922.1 - 0.0076 16.0 1.4 0.21 11.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EEQ30922.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EEQ30922.1 - 0.12 12.6 0.0 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ribosomal_S6 PF01250.17 EEQ30923.1 - 3.5e-23 81.7 0.0 4.4e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.19 EEQ30924.1 - 2.2e-41 140.5 2.2 2.7e-41 140.3 2.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EEQ30924.1 - 0.0014 18.5 0.2 0.002 18.0 0.2 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EEQ30924.1 - 0.0085 15.9 0.8 0.015 15.2 0.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 EEQ30924.1 - 0.068 12.9 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 zf-rbx1 PF12678.7 EEQ30925.1 - 1.1e-09 38.4 1.4 2.6e-09 37.2 1.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEQ30925.1 - 8.8e-08 32.4 9.0 1.2e-07 31.9 4.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ30925.1 - 4.8e-07 29.5 7.1 5.2e-07 29.4 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ30925.1 - 1.2e-06 28.4 3.5 3.5e-06 26.9 3.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EEQ30925.1 - 2.3e-06 27.3 1.0 4e-06 26.6 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ30925.1 - 0.00012 21.8 1.8 0.00012 21.8 1.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ30925.1 - 0.0002 21.3 5.6 0.00052 20.0 1.4 3.3 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EEQ30925.1 - 0.0002 21.2 1.4 0.0002 21.2 1.4 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EEQ30925.1 - 0.0019 17.9 10.2 0.0025 17.5 0.8 3.2 3 0 0 3 3 3 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EEQ30925.1 - 0.0026 17.3 0.9 0.0079 15.8 0.9 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EEQ30925.1 - 0.0041 17.1 1.2 0.01 15.8 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 EEQ30925.1 - 0.17 9.7 1.4 0.26 9.1 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) FANCL_C PF11793.8 EEQ30925.1 - 4 7.7 6.0 4.5 7.5 3.3 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 EEQ30925.1 - 4.6 7.4 7.1 0.41 10.8 2.0 1.8 2 0 0 2 2 2 0 RING-variant domain Cation_efflux PF01545.21 EEQ30926.1 - 2.5e-14 53.5 11.4 3.3e-14 53.1 11.4 1.1 1 0 0 1 1 1 1 Cation efflux family DnaB_2 PF07261.11 EEQ30927.1 - 0.0041 16.8 0.1 0.094 12.5 0.0 2.6 3 0 0 3 3 3 1 Replication initiation and membrane attachment Zds_C PF08632.10 EEQ30927.1 - 0.14 11.9 1.4 0.56 10.0 0.2 2.2 2 0 0 2 2 2 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term COMPASS-Shg1 PF05205.12 EEQ30929.1 - 4.4e-26 91.6 0.0 4.4e-26 91.6 0.0 2.0 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.18 EEQ30930.1 - 7e-30 103.9 0.2 8.6e-30 103.6 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2517 PF10725.9 EEQ30930.1 - 0.026 14.3 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) DUF4598 PF15370.6 EEQ30931.1 - 1.7e-27 96.1 1.2 1.7e-27 96.1 1.2 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Dppa2_A PF14049.6 EEQ30931.1 - 0.024 14.8 0.3 0.054 13.7 0.3 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates AF-4 PF05110.13 EEQ30931.1 - 0.069 11.2 19.9 0.075 11.1 19.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CENP-B_dimeris PF09026.10 EEQ30931.1 - 0.085 13.3 0.6 0.085 13.3 0.6 2.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Macoilin PF09726.9 EEQ30931.1 - 0.76 8.3 6.6 0.97 7.9 6.6 1.1 1 0 0 1 1 1 0 Macoilin family GDA1_CD39 PF01150.17 EEQ30932.1 - 1.5e-101 340.1 0.0 2.1e-101 339.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family IF3_C PF00707.22 EEQ30933.1 - 1.4e-09 37.8 0.4 2.6e-09 36.9 0.4 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EEQ30933.1 - 2.8e-07 30.7 0.7 7.1e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 EEQ30933.1 - 7e-07 29.1 0.2 1.1e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial translation initiation factor GTP_EFTU PF00009.27 EEQ30934.1 - 7.9e-58 195.2 0.0 1.1e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEQ30934.1 - 2.2e-21 76.2 0.0 4.7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEQ30934.1 - 2.4e-17 63.1 1.4 5.9e-17 61.8 1.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ30934.1 - 2.7e-05 24.2 0.0 6.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EEQ30934.1 - 0.02 14.5 0.2 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EEQ30934.1 - 0.031 14.2 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 EEQ30934.1 - 0.041 13.6 0.2 7.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SCAB-ABD PF16711.5 EEQ30934.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein Radical_SAM PF04055.21 EEQ30935.1 - 6.9e-15 55.8 0.0 4.3e-14 53.2 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EEQ30935.1 - 1e-08 35.6 0.2 2.6e-08 34.2 0.1 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EEQ30935.1 - 8.6e-08 32.3 0.0 1.8e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain ABM PF03992.16 EEQ30938.1 - 2.3e-06 27.6 0.9 0.031 14.4 0.0 3.0 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.16 EEQ30939.1 - 9.9e-40 136.5 57.1 9.9e-40 136.5 57.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ30939.1 - 6.3e-15 54.6 27.0 8.9e-15 54.1 27.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 EEQ30940.1 - 5.9e-05 23.1 8.8 0.00017 21.7 8.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LpxB PF02684.15 EEQ30940.1 - 0.02 13.8 2.6 0.065 12.1 2.0 1.9 2 0 0 2 2 2 0 Lipid-A-disaccharide synthetase FAM222A PF15258.6 EEQ30940.1 - 0.23 10.5 13.6 0.33 10.0 13.6 1.2 1 0 0 1 1 1 0 Protein family of FAM222A SMAP PF15477.6 EEQ30940.1 - 0.42 11.6 8.1 0.99 10.4 8.1 1.6 1 0 0 1 1 1 0 Small acidic protein family Spt20 PF12090.8 EEQ30940.1 - 0.55 9.8 23.4 0.93 9.1 23.4 1.3 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 EEQ30940.1 - 0.59 8.9 17.6 0.92 8.3 17.6 1.2 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 EEQ30940.1 - 0.61 10.0 20.6 1 9.3 20.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 EEQ30940.1 - 2 7.7 6.3 0.54 9.6 3.2 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Paired_CXXCH_1 PF09699.10 EEQ30940.1 - 2.1 8.2 9.4 8.1 6.3 0.4 3.4 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF4834 PF16118.5 EEQ30940.1 - 2.2 9.3 6.4 5.9 7.9 6.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EMC3_TMCO1 PF01956.16 EEQ30940.1 - 3.6 7.3 7.0 7.4 6.3 7.0 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DivIC PF04977.15 EEQ30940.1 - 5.9 6.7 12.3 42 4.0 10.7 2.4 2 0 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.16 EEQ30942.1 - 1.1e-23 83.7 44.3 3e-23 82.3 42.1 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ30942.1 - 1.8e-09 37.0 3.8 1.8e-09 37.0 3.8 3.4 4 1 1 5 5 5 1 Sugar (and other) transporter OATP PF03137.20 EEQ30942.1 - 0.00031 19.2 0.6 0.00078 17.9 0.6 1.7 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family T6SS_TssF PF05947.12 EEQ30942.1 - 0.021 13.4 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssF RHD3 PF05879.12 EEQ30943.1 - 0 1046.2 0.0 0 1046.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EEQ30943.1 - 3.6e-08 33.0 0.2 6.6e-08 32.1 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EEQ30943.1 - 9.1e-06 25.8 0.1 1.9e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 EEQ30943.1 - 6.9e-05 23.1 0.1 0.00043 20.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EEQ30943.1 - 0.00015 21.8 0.1 0.0004 20.4 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EEQ30943.1 - 0.00068 19.0 0.2 0.0014 18.0 0.2 1.5 1 0 0 1 1 1 1 Septin Transp_cyt_pur PF02133.15 EEQ30944.1 - 7e-83 278.8 28.9 8.3e-82 275.3 28.9 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin APH PF01636.23 EEQ30945.1 - 5.3e-06 26.5 0.0 3.2e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DIM1 PF02966.16 EEQ30946.1 - 1.3e-69 232.1 0.3 1.4e-69 232.0 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EEQ30946.1 - 0.0043 17.0 0.0 0.0054 16.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin 4HBT_2 PF13279.6 EEQ30947.1 - 2.9e-09 37.5 0.0 4.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.13 EEQ30948.1 - 2.6e-06 27.5 2.1 3e-06 27.4 0.2 2.1 3 0 0 3 3 3 1 Hypoxia induced protein conserved region DUF3425 PF11905.8 EEQ30949.1 - 2e-33 115.0 0.0 3.6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EEQ30949.1 - 0.026 14.6 4.5 0.047 13.8 4.5 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 EEQ30949.1 - 0.041 14.0 5.8 0.073 13.2 5.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper adh_short PF00106.25 EEQ30950.1 - 1.2e-06 28.1 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ30950.1 - 1.8e-05 24.8 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EEQ30950.1 - 0.004 16.8 0.0 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Med26 PF08711.11 EEQ30951.1 - 1.3e-10 41.1 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nup54 PF13874.6 EEQ30952.1 - 9.2e-42 142.5 0.4 9.2e-42 142.5 0.4 3.0 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EEQ30952.1 - 2.7e-12 46.0 1.6 2.7e-12 46.0 1.6 1.7 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 EEQ30952.1 - 1.4e-06 29.1 39.6 1.4e-06 29.1 39.6 2.9 1 1 1 2 2 2 1 Nucleoporin FG repeat region AAA PF00004.29 EEQ30953.1 - 2.3e-16 60.4 0.0 1.4e-15 57.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ30953.1 - 1.2e-12 48.6 0.5 2.3e-10 41.1 0.0 3.7 3 2 0 3 3 3 1 AAA ATPase domain AAA_lid_10 PF17872.1 EEQ30953.1 - 5.6e-12 45.6 0.5 2.1e-11 43.8 0.5 2.0 2 0 0 2 2 1 1 AAA lid domain AAA_22 PF13401.6 EEQ30953.1 - 1.4e-09 38.3 0.0 1.1e-08 35.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EEQ30953.1 - 0.00039 20.3 0.2 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEQ30953.1 - 0.00046 20.5 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EEQ30953.1 - 0.0016 18.7 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EEQ30953.1 - 0.0068 15.7 0.0 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 KAP family P-loop domain RNA_helicase PF00910.22 EEQ30953.1 - 0.009 16.4 0.0 0.097 13.1 0.0 2.8 4 0 0 4 4 3 1 RNA helicase NACHT PF05729.12 EEQ30953.1 - 0.0092 15.9 0.0 0.035 14.0 0.0 2.0 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EEQ30953.1 - 0.01 15.8 0.0 0.23 11.3 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EEQ30953.1 - 0.018 14.6 0.0 0.32 10.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_6 PF12774.7 EEQ30953.1 - 0.019 14.0 0.0 0.042 12.8 0.0 1.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 EEQ30953.1 - 0.028 14.6 0.0 0.33 11.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain BAH PF01426.18 EEQ30953.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 BAH domain PIF1 PF05970.14 EEQ30953.1 - 0.058 12.6 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase UvrD-helicase PF00580.21 EEQ30953.1 - 0.076 12.5 0.0 0.71 9.3 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain GGA_N-GAT PF18308.1 EEQ30953.1 - 0.11 12.1 0.4 0.27 10.9 0.4 1.6 1 0 0 1 1 1 0 GGA N-GAT domain DUF2075 PF09848.9 EEQ30953.1 - 0.14 11.4 0.0 0.56 9.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.32 EEQ30954.1 - 2e-39 132.9 14.1 9.5e-10 38.9 0.2 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ30954.1 - 3.9e-05 23.9 0.2 1.6 9.1 0.0 4.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ30954.1 - 0.031 12.9 1.8 10 4.6 0.0 3.7 2 2 2 4 4 4 0 Nucleoporin Nup120/160 Ank_2 PF12796.7 EEQ30955.1 - 1.1e-36 125.3 0.6 3.4e-14 53.2 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ30955.1 - 4.1e-30 103.7 7.9 1.6e-07 31.7 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ30955.1 - 4.4e-28 97.0 2.5 2e-09 37.5 0.0 3.5 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ30955.1 - 1.1e-25 86.8 1.3 0.00024 21.3 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EEQ30955.1 - 1e-20 73.2 1.1 0.00011 22.5 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat DUF484 PF04340.12 EEQ30955.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF484 Shal-type PF11601.8 EEQ30955.1 - 0.11 12.0 0.9 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels, N-terminal TMF_TATA_bd PF12325.8 EEQ30956.1 - 6.7e-40 135.9 10.3 6.7e-40 135.9 10.3 7.6 3 2 6 9 9 9 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EEQ30956.1 - 5.5e-21 74.4 12.4 5.5e-21 74.4 12.4 9.0 6 3 3 9 9 9 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EEQ30956.1 - 0.00014 22.1 3.0 0.00014 22.1 3.0 6.8 2 1 4 7 7 7 1 Autophagy protein 16 (ATG16) KxDL PF10241.9 EEQ30956.1 - 0.031 14.5 0.7 0.031 14.5 0.7 5.8 6 0 0 6 6 6 0 Uncharacterized conserved protein Drf_FH1 PF06346.12 EEQ30956.1 - 0.95 9.2 5.5 0.28 10.9 0.4 2.0 2 0 0 2 2 2 0 Formin Homology Region 1 NPV_P10 PF05531.12 EEQ30956.1 - 9.9 6.7 18.5 2.2 8.8 0.4 5.8 7 0 0 7 7 7 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.25 EEQ30957.1 - 6.8e-15 55.1 0.0 8.5e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ30957.1 - 3.3e-13 49.5 0.0 1.6e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PemK_toxin PF02452.17 EEQ30957.1 - 0.069 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system ACP_PD PF04336.12 EEQ30957.1 - 0.075 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase V-ATPase_H_N PF03224.14 EEQ30958.1 - 6.8e-82 275.3 0.0 9.3e-82 274.8 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EEQ30958.1 - 1.8e-36 124.8 0.0 5.3e-36 123.3 0.0 1.9 1 0 0 1 1 1 1 V-ATPase subunit H EFP PF01132.20 EEQ30959.1 - 0.037 14.1 0.1 0.094 12.8 0.1 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain TraI_2B PF18340.1 EEQ30959.1 - 0.065 13.3 0.0 0.26 11.4 0.0 2.0 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain Noelin-1 PF12308.8 EEQ30959.1 - 0.18 11.8 0.1 0.18 11.8 0.1 5.1 5 1 0 5 5 5 0 Neurogenesis glycoprotein Filament PF00038.21 EEQ30959.1 - 7.9 6.0 63.8 0.041 13.5 18.8 5.6 6 0 0 6 6 6 0 Intermediate filament protein MFS_1 PF07690.16 EEQ30960.1 - 1e-15 57.5 43.3 4.2e-15 55.5 43.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily CUE PF02845.16 EEQ30960.1 - 0.076 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 CUE domain Apq12 PF12716.7 EEQ30962.1 - 2.6e-21 75.3 13.6 3.6e-21 74.9 13.6 1.2 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.17 EEQ30963.1 - 5.7e-76 255.5 0.0 6.9e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EEQ30963.1 - 2.4e-05 24.2 0.0 0.0001 22.2 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EEQ30963.1 - 0.00015 21.8 0.0 0.00052 20.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ30963.1 - 0.00083 19.8 0.0 0.0021 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ30963.1 - 0.0017 18.6 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEQ30963.1 - 0.002 18.7 0.0 0.0032 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EEQ30963.1 - 0.0028 18.1 0.0 0.0057 17.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EEQ30963.1 - 0.0036 17.7 0.3 0.038 14.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EEQ30963.1 - 0.0048 16.9 0.0 0.0063 16.6 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 EEQ30963.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.27 EEQ30963.1 - 0.0058 16.2 0.2 4.7 6.7 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 EEQ30963.1 - 0.0064 16.0 0.2 0.032 13.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 EEQ30963.1 - 0.0069 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EEQ30963.1 - 0.0079 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_31 PF13614.6 EEQ30963.1 - 0.0085 16.0 0.0 1.3 9.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEQ30963.1 - 0.0098 15.0 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EEQ30963.1 - 0.017 14.9 0.0 0.051 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EEQ30963.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.12 EEQ30963.1 - 0.023 13.6 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 ATPase_2 PF01637.18 EEQ30963.1 - 0.025 14.5 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EEQ30963.1 - 0.028 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EEQ30963.1 - 0.032 14.2 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 EEQ30963.1 - 0.033 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EEQ30963.1 - 0.037 14.5 0.0 0.081 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 EEQ30963.1 - 0.048 13.0 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 EEQ30963.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PduV-EutP PF10662.9 EEQ30963.1 - 0.094 12.5 0.0 0.33 10.7 0.0 1.9 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EEQ30963.1 - 0.1 12.3 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EEQ30963.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.18 EEQ30963.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Septin KAP_NTPase PF07693.14 EEQ30963.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.23 EEQ30963.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 EEQ30963.1 - 0.13 11.8 0.1 0.59 9.7 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EEQ30963.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 EEQ30963.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase S-AdoMet_synt_C PF02773.16 EEQ30964.1 - 3.2e-57 192.4 0.0 6.8e-57 191.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 EEQ30964.1 - 1e-40 138.4 0.9 7.4e-40 135.6 0.9 2.2 1 1 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 EEQ30964.1 - 1.9e-13 50.7 0.0 5.4e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 EEQ30964.1 - 0.074 11.8 0.1 0.42 9.4 0.0 2.0 3 0 0 3 3 3 0 S-adenosylmethionine synthetase (AdoMet synthetase) SLD3 PF08639.10 EEQ30965.1 - 1.3e-156 522.5 5.6 1.3e-156 522.5 5.6 1.5 2 0 0 2 2 2 1 DNA replication regulator SLD3 HNH_2 PF13391.6 EEQ30966.1 - 3e-15 56.1 0.1 5.1e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease CRC_subunit PF08624.10 EEQ30967.1 - 1.6e-51 174.3 0.2 2.9e-51 173.4 0.2 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AT_hook PF02178.19 EEQ30967.1 - 8.1 6.7 9.6 36 4.7 9.6 2.2 1 0 0 1 1 1 0 AT hook motif Homeodomain PF00046.29 EEQ30968.1 - 3.8e-16 58.7 3.0 1.5e-15 56.8 2.7 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EEQ30968.1 - 0.00041 20.2 1.1 0.0013 18.6 1.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain RPN2_C PF18004.1 EEQ30968.1 - 0.32 10.9 11.0 0.8 9.6 11.0 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4638 PF15472.6 EEQ30968.1 - 2.8 7.6 12.5 0.24 11.1 7.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) Dicty_REP PF05086.12 EEQ30968.1 - 3.7 5.4 6.7 5.1 5.0 6.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HAD_2 PF13419.6 EEQ30969.1 - 2.4e-20 73.4 0.0 3.2e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ30969.1 - 1.1e-09 38.9 0.2 4.8e-06 27.0 0.0 2.4 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEQ30969.1 - 4.6e-05 23.9 0.0 6.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ30969.1 - 0.00011 22.2 0.1 0.00028 20.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EEQ30969.1 - 0.0021 18.1 0.2 0.045 13.9 0.2 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.11 EEQ30970.1 - 4e-24 84.5 15.1 1.1e-23 83.1 15.1 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EEQ30970.1 - 4.2e-18 65.5 0.8 3e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ30970.1 - 2.4e-07 30.8 0.0 2.1e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EEQ30970.1 - 4.9e-06 26.2 0.2 3.3e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EEQ30970.1 - 8.4e-05 22.7 3.3 0.68 10.0 0.2 3.7 3 1 0 4 4 4 2 Dynamin family GTP_EFTU PF00009.27 EEQ30970.1 - 0.00056 19.5 0.0 0.36 10.4 0.0 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EEQ30970.1 - 0.0065 15.8 0.2 0.024 14.0 0.1 1.9 2 0 0 2 2 2 1 AIG1 family MeaB PF03308.16 EEQ30970.1 - 0.015 14.3 0.1 0.044 12.7 0.1 1.8 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EEQ30970.1 - 0.021 14.4 3.0 0.56 9.8 0.0 3.4 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EEQ30970.1 - 0.077 13.5 0.0 0.27 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EEQ30970.1 - 0.12 12.7 0.0 9.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EEQ30970.1 - 0.41 11.0 0.0 0.41 11.0 0.0 3.2 2 1 0 2 2 1 0 AAA ATPase domain CBFD_NFYB_HMF PF00808.23 EEQ30971.1 - 5e-06 26.7 0.1 1e-05 25.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.10 EEQ30971.1 - 6.9 5.9 26.6 8.6 5.6 26.6 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 EEQ30971.1 - 8.5 5.0 10.7 25 3.5 10.7 1.6 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein SIR2 PF02146.17 EEQ30972.1 - 3.4e-27 95.5 0.0 1.2e-26 93.7 0.0 1.9 2 1 0 2 2 2 1 Sir2 family FAD_binding_4 PF01565.23 EEQ30972.1 - 0.016 14.9 0.0 0.046 13.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Med16 PF11635.8 EEQ30973.1 - 1.1e-173 579.2 0.0 1.2e-173 578.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 EEQ30973.1 - 0.034 14.5 0.0 2.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L29 PF00831.23 EEQ30974.1 - 3.2e-17 62.2 2.8 4.1e-17 61.9 0.1 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein V-SNARE_C PF12352.8 EEQ30975.1 - 8.2e-14 51.6 8.1 1.3e-13 51.0 0.2 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 EEQ30975.1 - 0.0092 14.7 5.2 0.011 14.5 5.2 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Sec20 PF03908.13 EEQ30975.1 - 0.016 15.1 2.5 5.5 7.0 0.0 3.3 2 1 2 4 4 4 0 Sec20 AAA_13 PF13166.6 EEQ30975.1 - 0.017 13.8 1.0 0.021 13.5 1.0 1.2 1 0 0 1 1 1 0 AAA domain NleF_casp_inhib PF16809.5 EEQ30975.1 - 0.03 14.2 1.2 0.13 12.1 0.8 1.9 1 1 1 2 2 2 0 NleF caspase inhibitor Syntaxin-6_N PF09177.11 EEQ30975.1 - 0.074 13.6 4.3 0.21 12.2 4.2 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Dor1 PF04124.12 EEQ30975.1 - 0.17 10.5 6.5 0.27 9.9 6.5 1.3 1 0 0 1 1 1 0 Dor1-like family Uso1_p115_C PF04871.13 EEQ30975.1 - 0.84 10.0 6.7 8.8 6.7 6.6 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 EEQ30975.1 - 1.1 9.1 8.3 7.2 6.5 1.0 3.3 3 1 1 4 4 4 0 Septum formation initiator APG6_N PF17675.1 EEQ30975.1 - 2.8 8.5 10.1 11 6.6 9.8 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region ATP-synt_10 PF05176.14 EEQ30976.1 - 1.4e-77 260.4 0.0 1.9e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.6 EEQ30977.1 - 5.3e-34 116.9 0.0 1.1e-33 115.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EEQ30977.1 - 5.4e-22 77.7 0.0 1.2e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EEQ30977.1 - 3.5e-18 65.2 0.6 1.2e-17 63.4 0.6 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EEQ30977.1 - 4.8e-17 62.1 0.3 1.5e-16 60.5 0.3 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 EEQ30977.1 - 0.044 14.1 0.1 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Nucleotidyltransferase domain Zn_clus PF00172.18 EEQ30978.1 - 0.014 15.5 8.8 0.033 14.3 8.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dmrt1 PF12374.8 EEQ30978.1 - 0.028 14.8 0.5 0.12 12.9 0.0 2.4 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 ACOX PF01756.19 EEQ30979.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA oxidase CPL PF08144.11 EEQ30980.1 - 1.1e-33 116.6 0.2 2.6e-29 102.4 0.0 3.9 4 0 0 4 4 4 2 CPL (NUC119) domain PRP21_like_P PF12230.8 EEQ30980.1 - 0.74 9.6 14.5 4.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein RRN3 PF05327.11 EEQ30980.1 - 1.3 7.4 11.9 9 4.7 8.9 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EEQ30980.1 - 1.5 6.9 23.3 2.3 6.3 23.3 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EEQ30980.1 - 2 6.6 15.9 3.3 5.9 15.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Rad51 PF08423.11 EEQ30983.1 - 2e-128 427.0 0.0 2.5e-128 426.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EEQ30983.1 - 1.2e-09 38.0 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EEQ30983.1 - 5.5e-08 32.6 0.0 7.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EEQ30983.1 - 2.5e-05 24.8 1.1 6.3e-05 23.5 0.5 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EEQ30983.1 - 0.00012 21.5 0.7 0.00054 19.4 0.7 2.0 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EEQ30983.1 - 0.0086 15.4 0.1 0.04 13.2 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain HHH PF00633.23 EEQ30983.1 - 0.02 14.8 0.4 11 6.1 0.1 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif ssDNA_TraI_N PF18272.1 EEQ30983.1 - 0.043 13.8 0.7 0.21 11.6 0.1 2.3 3 0 0 3 3 3 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 EEQ30983.1 - 0.091 11.9 0.1 0.33 10.0 0.0 1.8 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.8 EEQ30984.1 - 5.1e-133 444.6 5.9 8.6e-133 443.8 5.9 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_12 PF13424.6 EEQ30984.1 - 0.1 12.9 0.1 0.55 10.6 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3808 PF10300.9 EEQ30985.1 - 1.4e-127 426.3 0.0 6.4e-125 417.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) CIDR1_gamma PF18562.1 EEQ30985.1 - 0.0012 18.9 0.1 0.0033 17.5 0.1 1.7 1 0 0 1 1 1 1 Cysteine-Rich Interdomain Region 1 gamma DSS1_SEM1 PF05160.13 EEQ30986.1 - 2e-22 79.0 12.9 2.5e-22 78.7 12.9 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.19 EEQ30987.1 - 2.3e-148 494.2 0.5 2.6e-148 494.0 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 EEQ30987.1 - 0.00087 19.3 0.1 0.053 13.5 0.0 3.1 3 1 0 3 3 3 1 PA domain DUF3530 PF12048.8 EEQ30987.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Pyr_redox PF00070.27 EEQ30987.1 - 0.089 13.4 0.3 12 6.6 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-H2C2_2 PF13465.6 EEQ30988.1 - 2.8e-08 33.8 8.8 7.8e-07 29.2 0.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EEQ30988.1 - 1.1e-07 31.9 7.4 1.2e-05 25.5 0.5 3.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EEQ30988.1 - 4.2e-07 29.8 0.9 0.017 15.1 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EEQ30988.1 - 9.1e-06 26.2 7.1 0.085 13.5 0.1 3.2 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EEQ30988.1 - 7e-05 23.3 7.8 0.002 18.8 0.4 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EEQ30988.1 - 0.047 13.5 1.1 0.094 12.5 0.1 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 EEQ30988.1 - 0.13 12.0 3.8 0.33 10.8 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 EEQ30988.1 - 0.33 11.3 4.9 2.7 8.4 0.2 3.5 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zap1_zf2 PF18217.1 EEQ30988.1 - 1 9.4 7.5 4.2 7.4 0.9 2.5 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf_ZIC PF18366.1 EEQ30988.1 - 1.5 9.0 5.8 0.52 10.5 0.3 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain Sina PF03145.16 EEQ30988.1 - 2.2 8.2 5.6 15 5.5 0.7 2.2 1 1 0 2 2 2 0 Seven in absentia protein family SNF2_N PF00176.23 EEQ30989.1 - 1.1e-55 188.8 0.0 1.8e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EEQ30989.1 - 1.8e-24 85.4 0.4 2.2e-15 56.3 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 EEQ30989.1 - 7.8e-22 77.5 0.0 5.3e-21 74.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 EEQ30989.1 - 6e-18 65.2 0.0 2.1e-17 63.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EEQ30989.1 - 9.8e-07 28.2 0.0 2.8e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 EEQ30989.1 - 1e-06 29.1 19.6 1.1e-05 25.7 1.8 4.6 3 1 1 4 4 4 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 EEQ30989.1 - 4.5e-06 26.8 0.2 5.2e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 EEQ30989.1 - 0.023 14.9 0.2 0.21 11.7 0.0 2.7 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain AAA_22 PF13401.6 EEQ30989.1 - 0.026 14.8 0.0 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain SLIDE PF09111.10 EEQ30989.1 - 0.06 13.4 0.0 0.51 10.4 0.0 2.7 2 1 0 2 2 2 0 SLIDE ABC_tran PF00005.27 EEQ30990.1 - 7.2e-34 117.2 0.0 1.7e-15 57.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EEQ30990.1 - 3e-14 52.6 5.5 3e-14 52.6 5.5 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 EEQ30990.1 - 2.3e-11 43.6 2.8 0.0026 17.2 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEQ30990.1 - 4.1e-09 36.7 3.5 0.23 11.3 1.7 4.4 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EEQ30990.1 - 1.2e-06 28.6 0.0 0.038 13.9 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_15 PF13175.6 EEQ30990.1 - 1.2e-05 25.2 0.2 0.2 11.3 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 EEQ30990.1 - 3.7e-05 24.2 0.1 0.069 13.6 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ30990.1 - 4e-05 23.9 0.0 0.012 15.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain Fer4 PF00037.27 EEQ30990.1 - 7.3e-05 22.4 2.5 7.3e-05 22.4 2.5 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_7 PF12775.7 EEQ30990.1 - 0.00014 21.5 0.2 0.003 17.1 0.2 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EEQ30990.1 - 0.00052 20.0 0.2 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EEQ30990.1 - 0.00057 19.6 0.6 0.82 9.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EEQ30990.1 - 0.0011 19.4 0.0 0.28 11.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EEQ30990.1 - 0.0012 18.7 1.8 0.095 12.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ30990.1 - 0.0012 19.3 0.1 1.4 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EEQ30990.1 - 0.0012 18.5 3.0 0.03 14.0 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EEQ30990.1 - 0.0017 18.7 0.6 0.73 10.2 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Thymidylate_kin PF02223.17 EEQ30990.1 - 0.0032 17.2 0.3 2.2 7.9 0.0 3.0 3 0 0 3 3 3 1 Thymidylate kinase Fer4_6 PF12837.7 EEQ30990.1 - 0.0034 17.4 12.3 0.0077 16.3 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 EEQ30990.1 - 0.0039 17.3 11.8 0.0076 16.4 11.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 EEQ30990.1 - 0.0053 16.8 0.1 0.095 12.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EEQ30990.1 - 0.0055 15.9 1.9 1.4 8.1 0.0 3.4 3 1 1 4 4 4 1 NB-ARC domain AAA_33 PF13671.6 EEQ30990.1 - 0.01 16.0 0.1 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EEQ30990.1 - 0.013 14.1 0.6 0.02 13.6 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 EEQ30990.1 - 0.014 15.6 0.1 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EEQ30990.1 - 0.015 15.3 1.8 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Fer4_10 PF13237.6 EEQ30990.1 - 0.02 15.0 15.6 0.023 14.8 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_30 PF13604.6 EEQ30990.1 - 0.023 14.4 0.4 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EEQ30990.1 - 0.034 13.6 0.1 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DnaB_C PF03796.15 EEQ30990.1 - 0.037 13.4 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_5 PF07728.14 EEQ30990.1 - 0.045 13.8 0.2 2.6 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) VirE PF05272.11 EEQ30990.1 - 0.066 12.9 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_9 PF13187.6 EEQ30990.1 - 0.067 13.4 11.8 0.14 12.4 11.8 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EEQ30990.1 - 0.074 14.0 0.2 0.074 14.0 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_23 PF13476.6 EEQ30990.1 - 0.092 13.2 3.9 1 9.8 0.3 2.4 2 0 0 2 2 2 0 AAA domain Fer4_17 PF13534.6 EEQ30990.1 - 0.11 13.1 0.1 0.11 13.1 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain ATPase PF06745.13 EEQ30990.1 - 0.14 11.5 0.2 0.31 10.4 0.2 1.5 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.23 EEQ30990.1 - 0.25 11.4 0.5 34 4.5 0.4 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EEQ30990.1 - 0.27 11.0 2.4 0.31 10.8 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EEQ30990.1 - 0.48 10.3 3.8 4.2 7.2 0.2 2.8 3 0 0 3 3 3 0 NTPase Fer4_7 PF12838.7 EEQ30990.1 - 0.86 10.2 12.8 0.077 13.6 1.7 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 EEQ30990.1 - 1.9 8.8 9.9 0.25 11.5 1.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.19 EEQ30991.1 - 1.2e-56 188.7 16.4 6.2e-14 51.9 0.4 7.1 6 1 0 6 6 6 5 FF domain WW PF00397.26 EEQ30991.1 - 2.2e-17 62.8 15.5 6.5e-09 35.7 1.6 2.7 2 0 0 2 2 2 2 WW domain UCH PF00443.29 EEQ30991.1 - 0.029 13.9 0.0 0.074 12.5 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase RhoGAP-FF1 PF16512.5 EEQ30991.1 - 0.13 12.9 9.0 0.56 10.9 0.1 4.4 3 1 1 4 4 4 0 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 EEQ30991.1 - 0.98 9.7 7.3 13 6.1 0.3 2.8 1 1 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 EEQ30992.1 - 2.2e-89 300.0 0.2 7.7e-89 298.2 0.2 1.8 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 RuvB_N PF05496.12 EEQ30992.1 - 0.029 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain REC104 PF17378.2 EEQ30992.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Meiotic recombination protein REC104 Mpv17_PMP22 PF04117.12 EEQ30993.1 - 1.4e-18 66.8 0.1 3.4e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.16 EEQ30994.1 - 4e-23 81.9 26.8 2.4e-22 79.3 23.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 EEQ30994.1 - 9.8 6.5 9.8 5.9 7.2 3.2 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) p450 PF00067.22 EEQ30995.1 - 9.9e-61 205.9 0.0 1.1e-60 205.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.21 EEQ30996.1 - 9.3e-101 338.0 0.0 1.4e-100 337.4 0.0 1.3 1 0 0 1 1 1 1 Amidase Arm PF00514.23 EEQ30997.1 - 1.4e-94 307.5 9.9 8.6e-14 51.0 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EEQ30997.1 - 1e-26 93.2 1.3 3.9e-26 91.3 0.6 2.2 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 EEQ30997.1 - 4.7e-22 77.3 4.3 6e-22 76.9 2.9 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 EEQ30997.1 - 4.3e-20 71.9 0.0 4.2e-09 36.7 0.0 5.0 2 2 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.6 EEQ30997.1 - 1.6e-19 70.0 6.6 1.8e-08 34.7 0.1 6.3 5 2 2 7 7 7 3 HEAT-like repeat HEAT PF02985.22 EEQ30997.1 - 2e-18 64.9 0.2 1.8e-05 24.6 0.0 6.8 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.13 EEQ30997.1 - 1.5e-07 31.1 0.0 0.0072 15.8 0.0 3.5 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.8 EEQ30997.1 - 2e-05 24.6 0.0 1.6 8.8 0.0 4.6 3 2 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.20 EEQ30997.1 - 2.7e-05 22.9 0.0 0.005 15.5 0.0 2.9 1 1 0 2 2 2 1 Adaptin N terminal region HEAT_PBS PF03130.16 EEQ30997.1 - 0.00053 20.4 0.6 0.97 10.3 0.1 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 EEQ30997.1 - 0.0014 18.7 0.0 5.9 6.9 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 EEQ30997.1 - 0.026 14.5 0.1 16 5.6 0.0 3.2 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 EEQ30997.1 - 0.053 13.8 4.1 2.8 8.2 0.2 4.5 4 2 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 EEQ30997.1 - 0.1 12.2 0.0 39 3.7 0.0 3.7 2 1 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Gcn1_N PF12074.8 EEQ30997.1 - 0.12 11.6 0.0 13 4.9 0.0 2.5 2 1 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Mo25 PF08569.11 EEQ30997.1 - 0.13 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Mo25-like NUSAP PF16006.5 EEQ30997.1 - 0.4 10.4 7.8 0.57 9.9 7.8 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein POT1PC PF16686.5 EEQ30998.1 - 3e-48 163.6 1.6 3.9e-47 160.0 1.2 2.2 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EEQ30998.1 - 9.6e-21 74.1 0.0 2.6e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 CDC45 PF02724.14 EEQ30998.1 - 0.018 13.4 0.8 0.029 12.7 0.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Pneumo_att_G PF05539.11 EEQ30999.1 - 0.058 13.0 7.4 0.082 12.5 7.4 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G zf-CCCH_4 PF18044.1 EEQ30999.1 - 2.2 8.2 11.7 0.32 10.8 2.1 2.8 3 0 0 3 3 3 0 CCCH-type zinc finger TRAP_alpha PF03896.16 EEQ31000.1 - 6.2e-14 51.9 0.0 2.2e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit HA2 PF04408.23 EEQ31001.1 - 4.8e-17 62.2 0.6 2.3e-16 60.0 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EEQ31001.1 - 5.8e-15 55.4 0.0 1.1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EEQ31001.1 - 1.7e-12 47.7 0.0 3.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ31001.1 - 1.1e-11 44.8 0.1 2.6e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 EEQ31001.1 - 2.8e-10 40.5 0.1 6.3e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 RWD domain UBA PF00627.31 EEQ31001.1 - 0.0021 17.9 0.0 0.11 12.4 0.0 2.9 2 0 0 2 2 2 1 UBA/TS-N domain AAA_22 PF13401.6 EEQ31001.1 - 0.0096 16.2 0.7 0.054 13.8 0.7 2.3 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 EEQ31001.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC UBA_6 PF18039.1 EEQ31001.1 - 0.022 14.7 0.0 1.2 9.2 0.0 3.3 3 0 0 3 3 3 0 UBA-like domain T2SSE PF00437.20 EEQ31001.1 - 0.024 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DND1_DSRM PF14709.7 EEQ31001.1 - 0.038 14.3 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF1421 PF07223.11 EEQ31001.1 - 0.057 13.3 0.0 20 5.1 0.0 3.0 3 0 0 3 3 3 0 UBA-like domain (DUF1421) dsRBD2 PF17842.1 EEQ31001.1 - 0.075 13.2 0.2 0.22 11.7 0.0 1.9 2 0 0 2 2 1 0 Double-stranded RNA binding domain 2 AAA_29 PF13555.6 EEQ31001.1 - 0.11 12.3 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain BTRD1 PF17660.1 EEQ31001.1 - 0.18 11.7 0.4 0.86 9.5 0.3 2.3 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 Arylsulfotran_2 PF14269.6 EEQ31003.1 - 5.9e-119 396.9 0.1 8e-119 396.4 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EEQ31003.1 - 4.9e-15 55.3 0.0 1.4e-13 50.6 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) LOR PF04525.12 EEQ31003.1 - 0.031 13.9 0.0 0.093 12.3 0.0 1.8 2 0 0 2 2 2 0 LURP-one-related RasGEF PF00617.19 EEQ31004.1 - 4e-60 203.0 0.1 6.8e-60 202.3 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EEQ31004.1 - 1.3e-25 89.7 0.1 2.8e-25 88.6 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EEQ31004.1 - 8.7e-13 47.7 0.1 1.6e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EEQ31004.1 - 9.8e-11 41.2 0.1 2.4e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EEQ31004.1 - 1.1e-10 41.1 0.1 2.4e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EEQ31004.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 WW domain RHH_1 PF01402.21 EEQ31004.1 - 0.64 10.1 4.5 0.16 12.0 0.6 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HGTP_anticodon PF03129.20 EEQ31005.1 - 0.044 13.9 0.3 0.072 13.2 0.3 1.2 1 0 0 1 1 1 0 Anticodon binding domain Fungal_trans PF04082.18 EEQ31006.1 - 2e-19 69.6 2.7 3.2e-19 69.0 2.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EEQ31006.1 - 2.3e-07 30.9 13.4 7.3e-05 23.0 5.5 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ31006.1 - 0.012 16.4 14.8 0.77 10.8 1.3 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EEQ31006.1 - 0.012 16.0 18.3 0.25 11.9 7.6 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EEQ31006.1 - 0.026 15.2 0.5 1.7 9.4 0.0 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-CHY PF05495.12 EEQ31006.1 - 0.95 10.0 6.5 0.75 10.3 3.5 2.1 2 0 0 2 2 2 0 CHY zinc finger UPRTase PF14681.6 EEQ31007.1 - 4.6e-71 238.6 0.0 5.2e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EEQ31007.1 - 2.3e-06 27.2 0.0 4.6e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.15 EEQ31008.1 - 4.1e-32 110.4 7.2 1.5e-15 57.3 1.2 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Prion_bPrPp PF11587.8 EEQ31008.1 - 0.091 12.6 3.6 0.27 11.1 1.6 2.5 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal JAB PF01398.21 EEQ31009.1 - 4.1e-29 100.9 0.1 7.6e-29 100.1 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EEQ31009.1 - 1.1e-25 90.4 0.1 1.8e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EEQ31009.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain SRP1_TIP1 PF00660.17 EEQ31009.1 - 0.056 13.5 0.3 0.39 10.8 0.1 2.2 2 0 0 2 2 2 0 Seripauperin and TIP1 family Pkinase PF00069.25 EEQ31010.1 - 6e-21 75.0 0.0 7.9e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31010.1 - 1.2e-16 60.8 0.0 2.7e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ31010.1 - 0.00049 19.5 0.1 0.0009 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEQ31010.1 - 0.029 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EEQ31010.1 - 0.053 12.8 0.0 0.27 10.5 0.0 1.9 1 1 0 1 1 1 0 Kinase-like MAP65_ASE1 PF03999.12 EEQ31011.1 - 7.7e-70 236.3 29.3 6.9e-69 233.1 21.8 2.9 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) DUF1140 PF06600.11 EEQ31011.1 - 0.059 13.8 1.2 0.09 13.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) Spectrin PF00435.21 EEQ31011.1 - 0.06 13.8 12.1 0.43 11.1 0.7 4.0 2 1 0 2 2 2 0 Spectrin repeat Csm2_III-A PF03750.13 EEQ31011.1 - 0.068 14.0 1.3 0.12 13.2 0.2 2.0 2 0 0 2 2 2 0 Csm2 Type III-A Fzo_mitofusin PF04799.13 EEQ31011.1 - 0.076 12.6 0.7 0.3 10.6 0.7 2.0 1 0 0 1 1 1 0 fzo-like conserved region TMF_TATA_bd PF12325.8 EEQ31011.1 - 0.08 13.2 25.0 0.17 12.1 0.7 3.8 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Occludin_ELL PF07303.13 EEQ31011.1 - 0.51 11.1 5.1 4.2 8.2 0.1 3.6 2 1 0 2 2 2 0 Occludin homology domain RmuC PF02646.16 EEQ31011.1 - 0.53 9.4 5.8 2.5 7.2 1.6 2.8 1 1 1 2 2 2 0 RmuC family JAKMIP_CC3 PF16034.5 EEQ31011.1 - 0.82 9.6 9.6 0.15 12.0 4.4 2.4 2 0 0 2 2 2 0 JAKMIP CC3 domain CC2-LZ PF16516.5 EEQ31011.1 - 2 8.8 15.2 1.9 8.9 0.7 4.1 2 2 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator tRNA-synt_1c PF00749.21 EEQ31012.1 - 3.8e-91 305.3 0.0 5.1e-91 304.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 EEQ31013.1 - 1.3e-39 135.6 0.4 2.3e-39 134.9 0.4 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEQ31013.1 - 3.9e-22 78.1 3.3 6.5e-22 77.4 3.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EEQ31013.1 - 8.2e-13 48.5 17.9 1.5e-12 47.7 17.9 1.5 1 0 0 1 1 1 1 DnaJ central domain Malate_DH PF12434.8 EEQ31013.1 - 0.21 11.6 0.3 0.48 10.5 0.3 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Anti-TRAP PF15777.5 EEQ31013.1 - 0.77 9.8 11.9 0.76 9.8 1.3 2.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_10 PF16685.5 EEQ31013.1 - 0.99 9.6 6.6 5.8 7.1 0.6 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 PHD_4 PF16866.5 EEQ31013.1 - 2.7 8.2 6.7 0.34 11.0 0.4 2.6 2 1 1 3 3 3 0 PHD-finger RseC_MucC PF04246.12 EEQ31013.1 - 4.6 7.2 5.1 0.57 10.1 0.3 1.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TackOD1 PF18551.1 EEQ31013.1 - 4.7 6.8 7.6 1.9 8.1 1.0 2.2 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 4HBT PF03061.22 EEQ31014.1 - 3.5e-11 43.3 0.0 6.6e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EEQ31014.1 - 3.9e-05 24.1 0.0 5.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EEQ31014.1 - 0.00031 20.1 1.5 0.00048 19.5 1.2 1.3 1 1 0 1 1 1 1 Acyl-ACP thioesterase PseudoU_synth_2 PF00849.22 EEQ31015.1 - 3.8e-26 92.1 0.0 6e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.12 EEQ31015.1 - 0.035 14.2 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) S4 PF01479.25 EEQ31015.1 - 0.19 11.5 0.1 0.37 10.5 0.1 1.4 1 0 0 1 1 1 0 S4 domain Ribosomal_L32e PF01655.18 EEQ31016.1 - 2.4e-35 121.2 0.3 2.4e-35 121.2 0.3 2.3 1 1 1 2 2 2 1 Ribosomal protein L32 Sec2p PF06428.11 EEQ31016.1 - 2.7e-10 40.1 12.4 2.7e-10 40.1 12.4 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF2072 PF09845.9 EEQ31016.1 - 0.15 12.4 5.3 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 Zn-ribbon containing protein RAP1 PF07218.11 EEQ31016.1 - 0.2 9.9 5.5 0.25 9.6 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ATG16 PF08614.11 EEQ31016.1 - 0.29 11.3 34.1 1.8e+04 -5.2 34.1 2.6 1 1 0 1 1 0 0 Autophagy protein 16 (ATG16) SPX PF03105.19 EEQ31016.1 - 0.5 10.2 17.9 0.73 9.7 17.9 1.2 1 0 0 1 1 1 0 SPX domain zf-CpG_bind_C PF12269.8 EEQ31016.1 - 0.55 10.0 6.2 0.97 9.2 5.2 1.8 1 1 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Spc7 PF08317.11 EEQ31016.1 - 0.61 8.9 15.9 0.02 13.8 6.8 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Prominin PF05478.11 EEQ31016.1 - 0.63 7.9 1.4 0.91 7.4 1.4 1.1 1 0 0 1 1 1 0 Prominin FapA PF03961.13 EEQ31016.1 - 1.2 7.6 6.7 0.37 9.4 3.2 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A Lebercilin PF15619.6 EEQ31016.1 - 1.8 8.2 23.0 1.9 8.1 15.7 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease RasGAP_C PF03836.15 EEQ31016.1 - 1.8 8.7 10.4 2.4 8.3 1.1 2.3 2 0 0 2 2 2 0 RasGAP C-terminus DUF3584 PF12128.8 EEQ31016.1 - 3.5 5.0 19.9 0.0091 13.6 7.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) RRM_1 PF00076.22 EEQ31017.1 - 6.5e-15 54.7 0.0 1.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XH PF03469.14 EEQ31018.1 - 0.013 15.4 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 XH domain Tim17 PF02466.19 EEQ31018.1 - 1.3 9.4 5.1 84 3.6 5.1 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family 2-Hacid_dh_C PF02826.19 EEQ31019.1 - 7.1e-56 188.4 0.0 9.2e-56 188.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ31019.1 - 1.9e-14 53.5 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EEQ31019.1 - 2.6e-06 27.7 0.0 3.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 EEQ31019.1 - 0.0039 18.0 0.0 0.011 16.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EEQ31019.1 - 0.041 14.5 0.0 0.077 13.6 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PEP-CTERM PF07589.11 EEQ31019.1 - 0.19 11.9 0.5 13 6.1 0.0 2.6 2 0 0 2 2 2 0 PEP-CTERM motif zf-C2HE PF16278.5 EEQ31020.1 - 5.2e-20 71.7 0.7 1.4e-19 70.3 0.7 1.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EEQ31020.1 - 3e-15 56.7 1.3 1.1e-13 51.7 1.3 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EEQ31020.1 - 5.5e-12 46.3 0.6 1.8e-11 44.6 0.6 1.8 1 1 0 1 1 1 1 HIT domain Cyclin_N PF00134.23 EEQ31021.1 - 1.8e-44 150.5 0.6 3.9e-44 149.5 0.6 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEQ31021.1 - 9.3e-35 119.3 0.0 3.2e-34 117.6 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIA PF03153.13 EEQ31021.1 - 0.78 9.7 16.7 1.1 9.2 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.18 EEQ31022.1 - 0.00078 19.5 12.6 0.0016 18.5 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 EEQ31022.1 - 0.1 12.1 0.1 0.31 10.5 0.1 1.8 1 0 0 1 1 1 0 Histone chaperone domain CHZ RNA_pol_Rpc4 PF05132.14 EEQ31023.1 - 1.2e-33 116.7 0.2 1.2e-33 116.7 0.2 2.9 2 1 0 2 2 2 1 RNA polymerase III RPC4 YfdX PF10938.8 EEQ31023.1 - 0.048 13.6 2.2 0.096 12.6 2.2 1.5 1 0 0 1 1 1 0 YfdX protein KRE1 PF17056.5 EEQ31024.1 - 4.8e-08 32.6 0.0 7.8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 Apt1 PF10351.9 EEQ31025.1 - 8.3e-184 611.9 0.4 8.3e-184 611.9 0.4 2.1 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27 PF10344.9 EEQ31025.1 - 2.1e-176 588.7 0.0 2.9e-176 588.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 EEQ31025.1 - 4.1e-165 550.3 0.0 6.9e-165 549.5 0.0 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EEQ31025.1 - 1.1e-55 188.0 0.1 2.7e-55 186.7 0.0 1.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EEQ31025.1 - 2.3e-52 177.0 0.0 1.9e-51 174.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EEQ31025.1 - 3.8e-27 95.0 0.1 2.4e-26 92.4 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain CheZ PF04344.13 EEQ31025.1 - 0.1 12.5 1.2 3.5 7.5 0.1 3.2 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ B-block_TFIIIC PF04182.12 EEQ31027.1 - 7.4e-21 74.1 0.1 1.5e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 EEQ31027.1 - 0.011 15.6 0.9 0.12 12.3 0.0 2.9 3 0 0 3 3 3 0 MarR family HTH_36 PF13730.6 EEQ31027.1 - 0.13 12.2 0.0 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain UQ_con PF00179.26 EEQ31028.1 - 6.9e-19 67.9 0.0 1.1e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEQ31028.1 - 0.076 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 RWD domain DHHC PF01529.20 EEQ31029.1 - 3.8e-36 124.1 14.2 3.8e-36 124.1 14.2 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Rhomboid PF01694.22 EEQ31030.1 - 8.4e-34 116.7 9.5 2.4e-33 115.3 8.8 2.0 2 0 0 2 2 2 1 Rhomboid family DUF2177 PF09945.9 EEQ31030.1 - 0.13 12.4 9.6 0.55 10.3 0.4 3.7 3 1 1 4 4 4 0 Predicted membrane protein (DUF2177) DUF4231 PF14015.6 EEQ31030.1 - 0.39 11.2 2.3 13 6.4 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) GST_C_2 PF13410.6 EEQ31031.1 - 8.2e-05 22.6 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EEQ31031.1 - 0.061 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PSI_8 PF00796.18 EEQ31031.1 - 1.1 9.1 7.7 0.1 12.5 2.5 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VIII Kinetochor_Ybp2 PF08568.10 EEQ31032.1 - 8e-123 411.1 0.1 9.1e-123 410.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin SPT_ssu-like PF11779.8 EEQ31033.1 - 0.024 14.3 1.5 0.033 13.8 1.5 1.3 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like PLDc_2 PF13091.6 EEQ31035.1 - 1.9e-16 60.2 0.1 4.3e-07 29.9 0.0 3.6 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 EEQ31035.1 - 2.2e-13 49.8 0.8 4e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EEQ31035.1 - 0.11 11.6 0.2 0.63 9.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB GFA PF04828.14 EEQ31036.1 - 4.1e-20 71.9 1.5 6.8e-20 71.2 1.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cyanate_lyase PF02560.14 EEQ31037.1 - 1.1e-32 111.7 0.0 2.3e-32 110.7 0.0 1.5 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EEQ31037.1 - 0.00017 21.9 0.0 0.00024 21.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EEQ31037.1 - 0.0031 17.5 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 EEQ31037.1 - 0.011 16.1 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain zf-C2H2_4 PF13894.6 EEQ31038.1 - 1.9e-11 43.7 14.0 0.19 12.7 0.2 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 EEQ31038.1 - 2.7e-08 33.8 14.1 0.068 13.7 0.1 6.1 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EEQ31038.1 - 4.6e-06 26.8 11.1 0.053 13.8 0.2 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ31038.1 - 0.00023 21.4 17.0 0.033 14.6 0.2 5.0 6 0 0 6 6 4 2 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.14 EEQ31038.1 - 0.017 15.0 0.9 4.2 7.3 0.1 3.0 2 1 1 3 3 3 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 EEQ31038.1 - 0.028 14.3 3.3 1.4 8.8 1.9 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C2H2_3rep PF18868.1 EEQ31038.1 - 0.048 14.3 7.9 0.27 11.9 0.7 2.9 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-CSL PF05207.13 EEQ31038.1 - 0.051 13.3 6.0 1.2 8.9 0.3 2.7 2 0 0 2 2 2 0 CSL zinc finger zf-C2H2_9 PF16293.5 EEQ31038.1 - 0.075 12.9 5.5 7 6.6 0.7 3.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 EEQ31038.1 - 0.35 11.2 9.3 0.49 10.7 1.2 3.0 2 1 0 2 2 2 0 C2H2-type zinc ribbon zinc_ribbon_4 PF13717.6 EEQ31038.1 - 0.35 10.8 9.1 3.7 7.5 0.7 3.8 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 EEQ31038.1 - 0.39 11.1 19.0 1.1 9.6 2.9 4.1 2 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 EEQ31038.1 - 1.1 9.8 10.0 5 7.7 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 EEQ31038.1 - 1.4 9.1 11.4 0.37 10.9 1.1 3.7 2 1 1 3 3 3 0 Zinc ribbon domain FOXP-CC PF16159.5 EEQ31038.1 - 1.6 9.4 10.4 6.3 7.5 0.2 3.8 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C3HC4_2 PF13923.6 EEQ31038.1 - 4 7.4 10.5 4.3 7.2 0.9 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 EEQ31038.1 - 5 7.5 22.7 5.2 7.4 3.0 4.7 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 EEQ31038.1 - 6.1 7.4 8.7 11 6.6 0.3 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DZR PF12773.7 EEQ31038.1 - 6.9 6.8 11.4 7.9 6.6 3.0 3.2 2 1 0 2 2 2 0 Double zinc ribbon M16C_assoc PF08367.11 EEQ31040.1 - 0.0089 15.2 4.6 0.063 12.4 4.5 2.0 2 0 0 2 2 2 1 Peptidase M16C associated DUF349 PF03993.12 EEQ31040.1 - 0.14 12.5 4.9 39 4.6 4.9 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) MFS_1 PF07690.16 EEQ31041.1 - 2.3e-41 141.9 47.2 4.4e-40 137.7 40.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EEQ31041.1 - 0.00062 18.7 9.6 0.00062 18.7 9.6 2.2 2 0 0 2 2 2 2 MFS_1 like family FAD_binding_3 PF01494.19 EEQ31042.1 - 4.2e-18 65.7 0.0 2.3e-13 50.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EEQ31042.1 - 2.1e-05 24.3 0.0 0.00012 21.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EEQ31042.1 - 3.2e-05 23.5 0.2 0.00037 20.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ31042.1 - 4.4e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ31042.1 - 7.7e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EEQ31042.1 - 0.00019 20.7 0.0 0.00039 19.6 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EEQ31042.1 - 0.0005 18.9 0.0 0.001 17.9 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EEQ31042.1 - 0.0033 18.0 0.0 0.0071 16.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EEQ31042.1 - 0.0069 15.3 0.0 0.35 9.7 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EEQ31042.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 EEQ31042.1 - 0.029 13.4 0.0 0.083 11.9 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.18 EEQ31042.1 - 0.037 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1517 PF07466.11 EEQ31042.1 - 0.046 13.8 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) FAD_binding_2 PF00890.24 EEQ31042.1 - 0.06 12.4 0.1 0.19 10.8 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain DNA_pol_B PF00136.21 EEQ31043.1 - 1.6e-147 492.0 3.2 2.1e-147 491.5 3.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EEQ31043.1 - 3.6e-80 269.6 0.0 7.4e-80 268.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EEQ31043.1 - 3.3e-19 69.1 3.4 7e-19 68.1 3.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 EEQ31043.1 - 0.0005 20.1 0.1 0.0024 17.9 0.1 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 EEQ31043.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 EEQ31043.1 - 0.01 14.7 0.8 0.03 13.2 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral ETC_C1_NDUFA5 PF04716.14 EEQ31043.1 - 0.028 14.2 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 ETC complex I subunit conserved region C1_1 PF00130.22 EEQ31043.1 - 0.051 13.5 6.2 0.24 11.3 0.8 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_hydro_31 PF01055.26 EEQ31043.1 - 0.052 12.7 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Fungal_trans_2 PF11951.8 EEQ31044.1 - 5.5e-11 41.9 1.8 5.5e-11 41.9 1.8 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ31044.1 - 4.9e-08 33.0 9.6 8.7e-08 32.2 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CATSPERG PF15064.6 EEQ31044.1 - 0.043 11.6 0.0 0.06 11.2 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma Pkinase PF00069.25 EEQ31045.1 - 9.6e-32 110.4 0.0 5.4e-17 62.0 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31045.1 - 6.4e-13 48.6 0.0 3.6e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_47 PF01532.20 EEQ31046.1 - 1.1e-182 608.0 0.0 1.3e-182 607.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 LIP PF03583.14 EEQ31047.1 - 4e-75 252.8 0.0 5.6e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Syja_N PF02383.18 EEQ31048.1 - 3e-77 260.1 0.1 5.2e-77 259.3 0.1 1.4 1 0 0 1 1 1 1 SacI homology domain Nudix_N PF12535.8 EEQ31048.1 - 0.01 15.4 0.4 0.025 14.2 0.4 1.6 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Tti2 PF10521.9 EEQ31049.1 - 1.3e-90 303.8 1.5 2e-90 303.2 1.5 1.3 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 EEQ31050.1 - 4.3e-24 85.4 0.1 1.1e-23 84.0 0.1 1.8 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EEQ31050.1 - 4.1e-06 26.5 0.0 9.5e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EEQ31050.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Glyco_transf_8C PF08437.10 EEQ31050.1 - 0.061 13.4 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal TRAPPC-Trs85 PF12739.7 EEQ31051.1 - 4.3e-110 368.5 0.0 3.9e-108 362.0 0.0 2.0 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit NPH-II PF12011.8 EEQ31051.1 - 0.1 12.5 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NPH-II Snf7 PF03357.21 EEQ31054.1 - 2.3e-17 63.1 13.0 2.3e-17 63.1 13.0 1.9 1 1 1 2 2 2 1 Snf7 PspA_IM30 PF04012.12 EEQ31054.1 - 0.86 9.1 18.3 15 5.1 18.3 2.5 1 1 0 1 1 1 0 PspA/IM30 family Prefoldin_2 PF01920.20 EEQ31054.1 - 1.3 9.1 14.2 10 6.1 0.1 2.8 2 1 0 2 2 2 0 Prefoldin subunit DUF16 PF01519.16 EEQ31054.1 - 1.3 9.5 12.5 0.083 13.4 0.7 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF948 PF06103.11 EEQ31054.1 - 2.4 8.5 10.4 2.6e+02 2.0 7.2 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FKBP_N PF01346.18 EEQ31054.1 - 2.5 9.1 4.9 4.9 8.2 3.1 2.5 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase BLOC1_2 PF10046.9 EEQ31054.1 - 4.9 7.5 12.0 8.1 6.8 0.1 4.0 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C3HC4_2 PF13923.6 EEQ31055.1 - 1e-09 38.1 15.8 1e-09 38.1 15.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ31055.1 - 4.5e-07 29.6 13.1 4.5e-07 29.6 13.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EEQ31055.1 - 5.7e-07 29.3 8.1 5.7e-07 29.3 8.1 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 EEQ31055.1 - 2.9e-06 27.0 16.7 2.9e-06 27.0 16.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ31055.1 - 9.6e-06 25.5 16.2 9.6e-06 25.5 16.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.27 EEQ31055.1 - 1.5e-05 24.6 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.6 EEQ31055.1 - 5.9e-05 23.3 21.2 6.6e-05 23.2 16.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EEQ31055.1 - 8.6e-05 22.5 15.9 8.6e-05 22.5 15.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EEQ31055.1 - 0.00041 20.1 16.4 0.22 11.4 14.7 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EEQ31055.1 - 0.00073 19.6 16.6 0.00073 19.6 16.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Mob_synth_C PF06463.13 EEQ31055.1 - 0.01 15.8 4.4 0.022 14.7 4.4 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Rad50_zn_hook PF04423.14 EEQ31055.1 - 0.019 14.8 4.8 1.7 8.5 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 EEQ31055.1 - 0.082 13.0 3.7 0.19 11.8 3.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 EEQ31055.1 - 0.087 13.0 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 U-box domain Pinin_SDK_N PF04697.13 EEQ31055.1 - 0.4 11.3 4.2 0.18 12.5 0.5 2.0 2 0 0 2 2 2 0 pinin/SDK conserved region zf-rbx1 PF12678.7 EEQ31055.1 - 0.47 10.8 16.2 0.11 12.8 11.9 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EEQ31055.1 - 1 9.5 11.7 0.22 11.7 7.9 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-Nse PF11789.8 EEQ31055.1 - 6.1 6.7 13.2 0.85 9.5 8.2 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prim_Zn_Ribbon PF08273.12 EEQ31055.1 - 8.1 6.8 10.0 2.8 8.3 0.1 3.1 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-UDP PF14569.6 EEQ31055.1 - 9.7 6.4 11.2 27 5.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding RING-finger CDC27 PF09507.10 EEQ31056.1 - 3.7e-84 283.6 25.3 6.7e-84 282.7 25.3 1.4 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Glyco_hydro_125 PF06824.11 EEQ31057.1 - 7e-179 595.1 0.0 8e-179 594.9 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) RRM_1 PF00076.22 EEQ31058.1 - 0.0023 17.7 0.0 0.53 10.1 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pol_alpha_B_N PF08418.10 EEQ31058.1 - 1.2 9.1 14.6 2 8.3 0.7 2.9 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal NMD3 PF04981.13 EEQ31059.1 - 1.2e-79 267.3 3.9 1.8e-79 266.6 3.9 1.3 1 0 0 1 1 1 1 NMD3 family HypA PF01155.19 EEQ31059.1 - 0.5 10.4 9.5 2.1 8.4 1.3 3.0 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RsfS PF02410.15 EEQ31060.1 - 3.7e-11 43.3 0.0 1.2e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation HTH_30 PF13556.6 EEQ31060.1 - 0.14 12.0 0.0 0.79 9.6 0.0 2.3 2 1 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Pex2_Pex12 PF04757.14 EEQ31061.1 - 6.5e-55 186.2 1.6 9.5e-55 185.6 1.6 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EEQ31061.1 - 9.2e-07 28.9 2.8 1.6e-06 28.1 2.8 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EEQ31061.1 - 0.0005 19.8 2.4 0.001 18.9 1.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ31061.1 - 0.0029 17.6 2.5 0.0029 17.6 2.5 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EEQ31061.1 - 0.0032 17.3 1.2 0.0056 16.5 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ31061.1 - 0.0051 16.7 2.1 0.0095 15.8 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ31061.1 - 0.01 16.1 1.5 0.02 15.2 1.5 1.4 1 0 0 1 1 1 0 Ring finger domain Mito_carr PF00153.27 EEQ31062.1 - 3.2e-60 200.1 2.3 1.6e-21 76.0 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ31062.1 - 0.0027 16.9 0.0 1.4 8.1 0.0 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease DUF5007 PF16398.5 EEQ31062.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5007) WAC_Acf1_DNA_bd PF10537.9 EEQ31063.1 - 2.4e-40 137.1 2.3 3.3e-40 136.7 0.6 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EEQ31063.1 - 7.1e-23 80.9 0.3 7.1e-23 80.9 0.3 3.8 5 1 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EEQ31063.1 - 6.4e-18 64.8 1.2 1.3e-17 63.9 1.2 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EEQ31063.1 - 4.3e-10 38.9 0.0 1.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 CtIP_N PF10482.9 EEQ31063.1 - 7.3 6.7 13.5 4.6 7.3 0.9 3.5 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Alg6_Alg8 PF03155.15 EEQ31064.1 - 6.7e-173 576.1 26.1 7.8e-173 575.9 26.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.13 EEQ31065.1 - 9e-21 74.3 0.0 1.3e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family TMF_TATA_bd PF12325.8 EEQ31065.1 - 0.0045 17.2 3.4 0.0075 16.5 3.4 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding WXG100 PF06013.12 EEQ31065.1 - 0.0093 16.2 0.2 0.43 10.9 0.0 2.4 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF4349 PF14257.6 EEQ31065.1 - 0.011 15.2 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Spc7 PF08317.11 EEQ31065.1 - 0.11 11.3 2.5 0.16 10.8 2.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FemAB PF02388.16 EEQ31065.1 - 0.14 11.0 0.2 0.2 10.5 0.2 1.1 1 0 0 1 1 1 0 FemAB family Seryl_tRNA_N PF02403.22 EEQ31065.1 - 0.17 12.1 2.1 0.32 11.3 2.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 EEQ31065.1 - 0.2 11.8 3.8 0.45 10.7 3.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EEQ31065.1 - 0.27 11.3 3.8 0.6 10.1 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 EEQ31065.1 - 0.51 10.9 4.2 0.81 10.2 2.8 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 EEQ31065.1 - 0.67 10.1 4.5 2.4 8.3 3.9 1.9 1 1 1 2 2 2 0 Tropomyosin like Syntaxin_2 PF14523.6 EEQ31065.1 - 0.95 9.9 6.2 2 8.8 5.5 1.8 1 1 0 1 1 1 0 Syntaxin-like protein TMPIT PF07851.13 EEQ31065.1 - 1.1 8.4 3.3 1.8 7.8 3.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein Snapin_Pallidin PF14712.6 EEQ31065.1 - 1.4 9.4 5.8 2.9 8.4 5.8 1.5 1 0 0 1 1 1 0 Snapin/Pallidin CLZ PF16526.5 EEQ31065.1 - 1.6 9.1 5.8 5.5 7.4 0.8 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 EEQ31065.1 - 1.7 9.1 4.5 11 6.6 0.5 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.24 EEQ31065.1 - 2.5 8.0 8.0 6.7 6.6 1.2 2.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.11 EEQ31065.1 - 9.2 6.7 6.0 25 5.4 1.0 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) PHD PF00628.29 EEQ31066.1 - 1.2e-17 63.5 17.9 1.9e-11 43.7 7.8 2.4 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 EEQ31066.1 - 0.0026 17.4 6.9 0.21 11.2 2.4 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 EEQ31066.1 - 0.03 14.6 3.5 0.46 10.8 1.1 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain Prim_Zn_Ribbon PF08273.12 EEQ31066.1 - 1.2 9.4 5.3 2.4 8.5 1.0 2.7 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase PHD_2 PF13831.6 EEQ31066.1 - 1.2 8.7 9.8 2.5 7.7 1.3 3.4 3 0 0 3 3 3 0 PHD-finger Peptidase_M24 PF00557.24 EEQ31067.1 - 4.9e-09 36.2 0.0 6.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 ANAPC15 PF15243.6 EEQ31067.1 - 0.14 12.6 5.7 0.3 11.5 5.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 PBP1_TM PF14812.6 EEQ31067.1 - 3.4 8.1 9.1 7.6 7.0 9.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Exo_endo_phos PF03372.23 EEQ31068.1 - 2.5e-05 23.9 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.12 EEQ31069.1 - 3.6e-63 213.5 0.0 7.5e-62 209.2 0.0 2.3 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.11 EEQ31069.1 - 0.00011 22.4 1.1 0.00011 22.4 1.1 3.0 2 1 1 3 3 3 1 INO80 complex subunit Ies4 HEAT PF02985.22 EEQ31070.1 - 6.1e-08 32.3 0.6 0.094 13.0 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EEQ31070.1 - 2.7e-07 30.9 4.9 4.6e-06 26.9 2.0 3.5 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EEQ31070.1 - 1.9e-05 24.7 0.2 0.00098 19.2 0.0 3.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EEQ31070.1 - 0.0003 20.4 0.0 0.51 9.9 0.0 2.7 1 1 1 2 2 2 2 CLASP N terminal DUF3734 PF12536.8 EEQ31070.1 - 0.031 14.6 2.1 0.22 11.9 0.1 3.5 3 0 0 3 3 3 0 Patatin phospholipase MFS_1 PF07690.16 EEQ31071.1 - 2.6e-39 135.1 39.7 2.6e-39 135.1 39.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ31071.1 - 6.6e-06 25.2 15.2 6.6e-06 25.2 15.2 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter PHD PF00628.29 EEQ31072.1 - 5.1e-10 39.1 5.0 5.1e-10 39.1 5.0 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EEQ31072.1 - 2.3e-08 34.2 1.5 2.3e-08 34.2 1.5 3.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 EEQ31072.1 - 3.6e-07 30.4 6.0 4.6e-07 30.0 0.6 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EEQ31072.1 - 5.7e-06 26.1 1.8 5.7e-06 26.1 1.8 3.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEQ31072.1 - 9.1e-06 25.4 7.1 1.3e-05 24.9 0.9 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 PHD_2 PF13831.6 EEQ31072.1 - 9.8e-06 25.0 3.6 9.8e-06 25.0 3.6 1.7 2 0 0 2 2 1 1 PHD-finger zf-RING_5 PF14634.6 EEQ31072.1 - 1.4e-05 25.0 0.3 1.4e-05 25.0 0.3 2.9 4 0 0 4 4 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EEQ31072.1 - 1.5e-05 24.7 2.9 1.5e-05 24.7 2.9 2.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ31072.1 - 7e-05 22.6 0.8 7e-05 22.6 0.8 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EEQ31072.1 - 0.00043 20.3 0.2 0.00043 20.3 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EEQ31072.1 - 0.0027 17.7 1.6 0.0027 17.7 1.6 3.7 2 1 1 3 3 3 1 RING-type zinc-finger zinc_ribbon_16 PF17034.5 EEQ31072.1 - 0.011 15.9 0.5 0.028 14.7 0.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon like family zf-PHD-like PF15446.6 EEQ31072.1 - 0.018 14.7 0.3 0.018 14.7 0.3 2.2 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RING_4 PF14570.6 EEQ31072.1 - 0.67 9.8 7.4 0.057 13.2 0.8 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EEQ31072.1 - 2.6 8.1 6.7 2.8e+02 1.6 6.6 3.1 1 1 1 2 2 2 0 Double zinc ribbon FANCL_C PF11793.8 EEQ31072.1 - 7.2 6.9 7.8 0.79 9.9 0.2 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain Ribosomal_L37ae PF01780.19 EEQ31073.1 - 2.7e-40 136.3 11.5 3e-40 136.2 11.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EEQ31073.1 - 0.00028 21.0 1.5 0.00038 20.5 1.5 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EEQ31073.1 - 0.0031 17.4 2.8 0.0052 16.7 2.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.15 EEQ31073.1 - 0.026 14.5 4.6 1.1 9.4 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger DUF1451 PF07295.11 EEQ31073.1 - 0.036 14.1 0.4 0.051 13.6 0.4 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Sacchrp_dh_NADP PF03435.18 EEQ31074.1 - 1e-17 64.6 0.0 2.5e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EEQ31074.1 - 0.0043 17.5 0.0 0.012 16.0 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain FIT1_2 PF17357.2 EEQ31074.1 - 0.069 13.2 0.2 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 Abhydrolase_1 PF00561.20 EEQ31075.1 - 1e-16 61.4 0.1 7.2e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ31075.1 - 1e-12 49.2 0.0 1.4e-12 48.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ31075.1 - 2.7e-09 36.6 0.0 1.1e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Pinin_SDK_memA PF04696.13 EEQ31076.1 - 1.6e-33 115.5 6.5 1.6e-33 115.5 6.5 2.8 1 1 2 3 3 3 1 pinin/SDK/memA/ protein conserved region NAP PF00956.18 EEQ31076.1 - 1.7 7.8 11.5 0.31 10.2 3.5 2.3 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) DIOX_N PF14226.6 EEQ31077.1 - 2.8e-29 102.3 0.0 4.1e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EEQ31077.1 - 3.8e-11 43.4 0.0 7.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Myb_DNA-binding PF00249.31 EEQ31078.1 - 5.8e-23 80.8 19.2 5.2e-10 39.3 2.3 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ31078.1 - 1e-22 80.1 12.1 2.2e-13 50.2 0.5 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EEQ31078.1 - 0.021 14.8 0.0 0.16 12.0 0.0 2.3 1 1 2 3 3 3 0 SLIDE MADF_DNA_bdg PF10545.9 EEQ31078.1 - 0.11 12.9 6.5 0.16 12.3 0.9 3.1 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 EEQ31078.1 - 0.37 10.9 8.8 1.9 8.6 0.2 3.8 2 1 2 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.16 EEQ31079.1 - 1.2e-37 129.7 47.5 2.1e-37 128.9 46.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ31079.1 - 4.1e-12 45.3 12.1 6.2e-12 44.7 12.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4728 PF15860.5 EEQ31079.1 - 0.068 13.9 4.8 0.29 11.8 0.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) p450 PF00067.22 EEQ31080.1 - 4.1e-55 187.3 0.0 5.2e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 EEQ31081.1 - 3.2e-71 239.9 0.0 5.2e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 EEQ31081.1 - 4.8e-35 119.3 0.8 1.5e-34 117.7 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 EEQ31081.1 - 2.9e-30 104.7 0.0 6.1e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EEQ31081.1 - 3.9e-22 79.2 0.0 4.2e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.12 EEQ31081.1 - 1.5e-21 76.7 0.0 2.4e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein SAT PF16073.5 EEQ31081.1 - 2.4e-16 60.2 0.2 1.4e-09 38.1 0.1 2.6 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 EEQ31081.1 - 7.4e-14 52.3 0.0 1.8e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ31081.1 - 2.2e-10 41.1 0.0 6.3e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EEQ31081.1 - 3.3e-10 40.2 0.2 9.3e-10 38.7 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EEQ31081.1 - 8.2e-10 38.8 0.0 4.9e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ31081.1 - 2e-09 37.4 0.0 5.8e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ31081.1 - 4.2e-09 36.9 0.0 1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EEQ31081.1 - 6e-08 32.5 0.0 1.5e-07 31.1 0.0 1.7 2 0 0 2 2 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 EEQ31081.1 - 1.3e-07 31.2 2.9 8.6e-06 25.3 0.1 2.7 3 0 0 3 3 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EEQ31081.1 - 3.6e-05 24.2 0.0 9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ubie_methyltran PF01209.18 EEQ31081.1 - 7e-05 22.3 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.15 EEQ31081.1 - 0.0032 16.6 0.0 0.02 14.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NodS PF05401.11 EEQ31081.1 - 0.0058 16.3 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Nodulation protein S (NodS) DXP_reductoisom PF02670.16 EEQ31081.1 - 0.012 16.3 0.0 0.043 14.5 0.0 2.0 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RmlD_sub_bind PF04321.17 EEQ31081.1 - 0.052 12.6 0.0 9.9 5.2 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 EEQ31081.1 - 0.055 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 KR domain PCMT PF01135.19 EEQ31081.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 EEQ31081.1 - 0.12 11.4 0.1 0.48 9.4 0.0 1.9 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase DUF4901 PF16244.5 EEQ31082.1 - 0.007 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4901) GRDP-like PF07173.12 EEQ31084.1 - 6.5e-21 75.5 0.5 7.7e-17 62.3 0.1 2.3 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Lipase_3 PF01764.25 EEQ31085.1 - 2.4e-18 66.3 0.0 3.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EEQ31085.1 - 0.017 15.8 0.1 0.042 14.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.14 EEQ31085.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) COesterase PF00135.28 EEQ31085.1 - 0.19 10.6 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family PHF5 PF03660.14 EEQ31086.1 - 4.3e-52 174.7 9.5 4.9e-52 174.5 9.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EEQ31086.1 - 0.47 8.3 6.8 0.49 8.2 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EEQ31086.1 - 1.9 8.6 15.3 2.3 8.3 1.1 3.0 1 1 1 2 2 2 0 Double zinc ribbon Cofilin_ADF PF00241.20 EEQ31087.1 - 3e-29 101.3 0.0 7.2e-17 61.3 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.27 EEQ31088.1 - 7.1e-67 221.4 0.9 1.5e-22 79.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CAF1 PF04857.20 EEQ31090.1 - 4.5e-68 229.8 0.0 1.1e-66 225.2 0.0 2.1 1 1 0 1 1 1 1 CAF1 family ribonuclease TFIIF_alpha PF05793.12 EEQ31091.1 - 0.003 16.2 13.5 0.0043 15.7 13.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDHD PF02862.17 EEQ31091.1 - 0.19 11.8 5.3 0.34 11.1 5.3 1.6 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 EEQ31091.1 - 0.21 9.8 13.3 0.31 9.3 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 EEQ31091.1 - 0.25 11.2 19.0 0.47 10.3 19.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1266 PF06889.11 EEQ31091.1 - 0.4 10.7 5.4 0.3 11.1 3.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) TRAP_alpha PF03896.16 EEQ31091.1 - 1.4 8.1 6.0 61 2.7 0.0 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4407 PF14362.6 EEQ31091.1 - 1.6 8.0 7.5 2.7 7.2 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 EEQ31091.1 - 2.5 7.9 18.3 1.4 8.7 16.5 1.5 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 EEQ31091.1 - 4.5 7.0 6.8 8.8 6.0 6.8 1.6 1 0 0 1 1 1 0 Connexin Borrelia_P83 PF05262.11 EEQ31091.1 - 5 5.5 15.2 7.1 5.0 15.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FAM178 PF14816.6 EEQ31091.1 - 8.5 5.2 14.0 19 4.1 14.0 1.5 1 0 0 1 1 1 0 Family of unknown function, FAM178 Neur_chan_memb PF02932.16 EEQ31091.1 - 9.3 6.2 10.5 19 5.2 10.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MRP-L46 PF11788.8 EEQ31092.1 - 9.7e-39 132.8 0.2 1.4e-38 132.3 0.2 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 LEA_3 PF03242.13 EEQ31092.1 - 0.051 14.3 0.3 0.12 13.1 0.3 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant protein Cript PF10235.9 EEQ31093.1 - 7.4e-25 87.3 11.6 7.4e-25 87.3 11.6 1.9 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 EEQ31093.1 - 0.0052 16.8 15.5 0.57 10.2 10.8 2.9 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 EEQ31093.1 - 0.023 15.4 14.0 0.066 14.0 10.5 2.7 2 1 0 2 2 2 0 zinc-ribbon family CEBP_ZZ PF16366.5 EEQ31093.1 - 0.097 12.9 8.9 0.063 13.5 5.5 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zinc_ribbon_2 PF13240.6 EEQ31093.1 - 0.12 12.2 11.5 2.7 7.8 3.5 3.3 3 0 0 3 3 3 0 zinc-ribbon domain FYVE PF01363.21 EEQ31093.1 - 0.38 10.9 11.9 1.3 9.2 7.6 2.4 1 1 1 2 2 2 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 EEQ31093.1 - 1.3 9.0 9.1 2 8.4 5.9 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-BED PF02892.15 EEQ31093.1 - 2.9 8.0 10.3 0.59 10.2 3.7 2.4 2 1 0 2 2 2 0 BED zinc finger DUF1272 PF06906.11 EEQ31093.1 - 4.3 7.5 8.6 1.6 8.9 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF2039 PF10217.9 EEQ31093.1 - 5.6 7.4 18.5 3.5 8.0 12.3 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1349 PF07081.11 EEQ31094.1 - 1.4e-23 83.6 0.0 3.7e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) AMPK1_CBM PF16561.5 EEQ31095.1 - 3.9e-07 30.2 0.1 1e-06 28.8 0.1 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase JIP_LZII PF16471.5 EEQ31096.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II NOC3p PF07540.11 EEQ31097.1 - 1.4e-29 102.4 0.3 4e-29 100.9 0.3 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 EEQ31097.1 - 1.1e-25 90.6 0.2 3e-24 86.0 0.1 2.5 2 0 0 2 2 2 1 CBF/Mak21 family UPF0113_N PF17833.1 EEQ31098.1 - 2.1e-25 89.1 0.0 2.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EEQ31098.1 - 2.9e-23 81.9 0.0 4.2e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain Cullin_binding PF03556.15 EEQ31099.1 - 3.7e-30 104.8 5.2 6.3e-30 104.1 5.2 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EEQ31099.1 - 1.8e-14 53.3 0.0 4.8e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain TAP_C PF03943.13 EEQ31099.1 - 0.0075 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain SprT-like PF10263.9 EEQ31100.1 - 2.4e-10 40.2 0.0 5.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Mpv17_PMP22 PF04117.12 EEQ31101.1 - 1.4e-12 47.6 1.7 3.2e-11 43.3 0.8 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family CKAP2_C PF15297.6 EEQ31101.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus XK-related PF09815.9 EEQ31102.1 - 0.071 12.2 2.5 0.08 12.0 2.5 1.0 1 0 0 1 1 1 0 XK-related protein DUF4771 PF15995.5 EEQ31103.1 - 0.025 14.8 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) PEX11 PF05648.14 EEQ31104.1 - 6.6e-17 61.7 1.2 2.4e-14 53.4 1.2 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) GGACT PF06094.12 EEQ31107.1 - 5.7e-06 26.9 0.0 1.3e-05 25.8 0.0 1.5 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like AAA PF00004.29 EEQ31108.1 - 9.7e-97 320.5 0.0 2e-47 160.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ31108.1 - 1.9e-23 82.0 5.8 6.7e-13 48.2 0.3 3.4 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EEQ31108.1 - 1e-18 67.3 1.4 2.3e-18 66.1 0.6 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EEQ31108.1 - 2.8e-14 53.6 0.0 1.1e-07 32.2 0.0 3.0 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EEQ31108.1 - 8.5e-14 51.6 0.2 1.4e-05 24.9 0.0 3.5 5 1 0 5 5 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EEQ31108.1 - 1.9e-12 47.6 0.0 2.3e-05 24.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EEQ31108.1 - 3.6e-11 43.7 0.0 0.00014 22.2 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EEQ31108.1 - 3.5e-10 40.0 0.6 4.5e-05 23.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ31108.1 - 6.5e-09 36.2 0.5 0.053 13.8 0.0 4.1 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 EEQ31108.1 - 7.5e-09 35.3 0.1 0.0015 17.8 0.0 2.6 2 1 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EEQ31108.1 - 4.9e-08 32.6 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 EEQ31108.1 - 3.1e-07 30.3 0.0 0.02 14.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEQ31108.1 - 4.4e-07 29.5 0.4 0.033 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EEQ31108.1 - 1.1e-06 28.2 0.4 0.64 9.3 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_18 PF13238.6 EEQ31108.1 - 1.1e-06 29.2 0.0 0.055 14.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 EEQ31108.1 - 1.9e-06 28.2 0.0 0.028 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EEQ31108.1 - 2.4e-06 27.6 0.0 0.023 14.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EEQ31108.1 - 3.8e-06 26.8 0.7 3.2e-05 23.8 0.2 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 EEQ31108.1 - 4.5e-06 26.4 6.5 0.43 10.1 0.1 4.9 3 2 1 5 5 5 2 AAA domain AAA_7 PF12775.7 EEQ31108.1 - 7.1e-06 25.6 0.1 0.035 13.6 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 EEQ31108.1 - 3e-05 24.3 0.0 0.3 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EEQ31108.1 - 3.7e-05 23.0 0.0 0.0086 15.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EEQ31108.1 - 4.9e-05 23.9 0.0 0.26 11.8 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 EEQ31108.1 - 7.5e-05 22.5 0.1 0.75 9.5 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 EEQ31108.1 - 8.3e-05 22.1 0.4 0.35 10.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.6 EEQ31108.1 - 8.5e-05 22.4 0.0 0.66 9.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 EEQ31108.1 - 0.00011 21.5 0.1 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 EEQ31108.1 - 0.00024 21.0 0.0 0.69 9.7 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein ResIII PF04851.15 EEQ31108.1 - 0.0004 20.4 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 EEQ31108.1 - 0.00043 20.7 0.0 0.88 10.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EEQ31108.1 - 0.0005 19.9 0.0 0.53 10.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 EEQ31108.1 - 0.0006 19.8 0.0 0.62 10.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EEQ31108.1 - 0.00074 19.4 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EEQ31108.1 - 0.0018 17.6 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EEQ31108.1 - 0.0039 16.9 0.6 2.6 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EEQ31108.1 - 0.0044 17.0 0.0 11 5.8 0.0 3.6 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EEQ31108.1 - 0.0053 17.1 0.7 6.9 7.0 0.0 3.5 3 1 0 4 4 2 0 AAA domain NACHT PF05729.12 EEQ31108.1 - 0.0071 16.3 0.1 1.6 8.6 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Viral_helicase1 PF01443.18 EEQ31108.1 - 0.0079 16.0 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UFD1 PF03152.14 EEQ31108.1 - 0.0086 15.6 0.0 0.069 12.6 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 KAP_NTPase PF07693.14 EEQ31108.1 - 0.019 14.2 0.0 0.73 9.0 0.0 2.6 2 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.6 EEQ31108.1 - 0.022 14.9 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EEQ31108.1 - 0.026 13.8 1.5 6.2 6.0 0.0 3.1 4 0 0 4 4 3 0 Zeta toxin NB-ARC PF00931.22 EEQ31108.1 - 0.027 13.7 0.0 1.9 7.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain IPT PF01745.16 EEQ31108.1 - 0.029 13.8 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase eIF-1a PF01176.19 EEQ31108.1 - 0.03 14.1 0.8 1.1 9.2 0.7 2.8 2 1 0 2 2 1 0 Translation initiation factor 1A / IF-1 NTPase_1 PF03266.15 EEQ31108.1 - 0.052 13.5 3.0 3.7 7.4 0.0 4.1 5 0 0 5 5 4 0 NTPase LXG PF04740.12 EEQ31108.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily T2SSE PF00437.20 EEQ31108.1 - 0.085 11.9 0.0 3.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_6 PF12774.7 EEQ31108.1 - 0.11 11.4 0.1 11 4.9 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Zot PF05707.12 EEQ31108.1 - 0.13 11.8 0.0 7 6.2 0.0 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) EnY2 PF10163.9 EEQ31109.1 - 3.1e-07 30.7 0.0 5.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.17 EEQ31110.1 - 1.9e-15 56.7 0.0 3.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EEQ31110.1 - 3.4e-12 46.6 0.0 5.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EEQ31110.1 - 3.5e-12 46.8 0.0 7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 EEQ31110.1 - 0.035 14.1 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Nha1_C PF08619.10 EEQ31111.1 - 3.8e-86 290.1 21.0 4.5e-86 289.9 21.0 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EEQ31111.1 - 1.8e-72 244.3 17.7 2.1e-72 244.0 17.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EEQ31111.1 - 0.025 14.7 0.4 0.025 14.7 0.4 2.4 3 0 0 3 3 3 0 YrhC-like protein DUF21 PF01595.20 EEQ31111.1 - 0.49 10.1 2.3 1.5 8.5 2.3 1.8 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain PX PF00787.24 EEQ31112.1 - 3.7e-17 62.3 0.1 6.9e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.9 EEQ31112.1 - 0.037 13.2 1.0 0.066 12.4 1.0 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MAGE_N PF12440.8 EEQ31112.1 - 0.043 14.5 1.4 0.043 14.5 1.4 3.2 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal Blo-t-5 PF11642.8 EEQ31112.1 - 0.12 12.4 1.4 13 5.8 0.0 2.3 1 1 0 2 2 2 0 Mite allergen Blo t 5 AAA PF00004.29 EEQ31113.1 - 5.4e-08 33.3 0.2 4.9e-07 30.2 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEQ31113.1 - 2.9e-07 30.6 0.9 7.8e-05 22.7 0.0 3.7 3 1 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 EEQ31113.1 - 0.0026 18.0 0.0 0.0092 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEQ31113.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EEQ31113.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEQ31113.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EEQ31113.1 - 0.066 13.7 0.2 0.26 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EEQ31113.1 - 0.084 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain T2SSE PF00437.20 EEQ31113.1 - 0.098 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 EEQ31113.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 EEQ31113.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase DUF815 PF05673.13 EEQ31113.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Utp8 PF10395.9 EEQ31114.1 - 6.1e-05 21.7 0.1 0.0034 16.0 0.3 2.7 2 1 0 2 2 2 1 Utp8 family Fungal_trans PF04082.18 EEQ31115.1 - 4.2e-21 75.2 0.9 6.6e-21 74.5 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EEQ31115.1 - 2.5e-09 37.1 14.8 7.3e-05 23.0 2.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ31115.1 - 1.1e-06 28.8 13.6 3.2e-06 27.3 6.6 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ31115.1 - 0.00012 22.6 13.5 0.041 14.7 2.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EEQ31115.1 - 1.3 9.1 4.0 4 7.5 4.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger CAF1C_H4-bd PF12265.8 EEQ31118.1 - 1e-15 57.7 0.1 5.2e-15 55.5 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EEQ31118.1 - 5.2e-14 52.4 7.6 2.5e-06 28.1 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ31118.1 - 1.1e-07 32.0 2.0 0.00071 19.8 0.3 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 EEQ31118.1 - 0.17 12.0 0.0 0.55 10.4 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus UL41A Ras PF00071.22 EEQ31119.1 - 4.3e-27 94.7 0.1 7.6e-27 93.9 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ31119.1 - 1.2e-23 83.6 0.1 2.7e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ31119.1 - 1.9e-06 27.4 0.1 3.2e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ31119.1 - 0.00049 19.5 0.1 0.00089 18.7 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EEQ31119.1 - 0.033 13.4 2.2 0.49 9.5 0.2 2.4 1 1 0 2 2 2 0 G-protein alpha subunit CrgA PF06781.12 EEQ31119.1 - 0.17 12.0 0.1 0.41 10.7 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA YajC PF02699.15 EEQ31119.1 - 0.26 11.2 1.4 0.57 10.1 1.4 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit TFIIA PF03153.13 EEQ31119.1 - 0.65 9.9 26.0 0.86 9.5 26.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EEQ31119.1 - 1.1 7.9 6.2 1.5 7.4 6.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1387 PF07139.11 EEQ31119.1 - 2.1 8.0 11.8 3.4 7.3 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) LAP1C PF05609.12 EEQ31119.1 - 8.3 5.4 14.1 11 4.9 14.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Transglut_core PF01841.19 EEQ31120.1 - 7.4e-12 45.7 0.0 1.4e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sugar_tr PF00083.24 EEQ31121.1 - 4.3e-91 306.0 19.6 5.5e-86 289.2 9.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EEQ31121.1 - 3e-22 79.0 20.0 3e-22 79.0 20.0 2.6 1 1 1 3 3 3 1 Major Facilitator Superfamily MFS_5 PF05631.14 EEQ31121.1 - 0.00013 21.1 0.5 0.00024 20.1 0.5 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 EEQ31121.1 - 0.0038 15.7 1.4 0.0065 14.9 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 EEQ31121.1 - 0.083 13.1 2.3 0.45 10.8 2.3 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) TRAM_LAG1_CLN8 PF03798.16 EEQ31122.1 - 7.7e-39 133.5 19.7 1.2e-38 132.8 19.7 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EEQ31122.1 - 2.7e-22 78.2 0.1 1.1e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein REC114-like PF15165.6 EEQ31123.1 - 0.33 10.7 3.6 0.52 10.0 3.6 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like SAPS PF04499.15 EEQ31123.1 - 2.2 6.9 6.9 2.2 7.0 6.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Endostatin PF06482.11 EEQ31123.1 - 2.5 7.5 4.7 2.5 7.5 4.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin TIP120 PF08623.10 EEQ31124.1 - 1.4e-65 220.2 0.0 6.1e-64 214.8 0.0 3.3 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EEQ31124.1 - 7.1e-12 44.5 5.5 0.94 9.9 0.0 9.3 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 EEQ31124.1 - 1e-07 32.2 7.5 2.3 8.7 0.0 7.6 6 2 2 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 EEQ31124.1 - 2.6e-06 27.8 5.0 64 4.2 0.0 9.9 11 1 1 12 12 12 0 HEAT-like repeat Cnd1 PF12717.7 EEQ31124.1 - 0.00034 20.7 0.3 0.066 13.2 0.0 3.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EEQ31124.1 - 0.00074 20.1 0.0 1.7 9.3 0.0 5.4 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EEQ31124.1 - 0.0017 18.5 0.2 0.39 10.9 0.0 4.2 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3295 PF11702.8 EEQ31124.1 - 0.0097 15.3 0.3 0.016 14.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DRIM PF07539.12 EEQ31124.1 - 0.067 11.5 4.5 22 3.2 0.1 4.3 4 1 1 5 5 5 0 Down-regulated in metastasis HEAT_PBS PF03130.16 EEQ31124.1 - 3 8.8 7.2 1.1 10.1 0.1 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat PalH PF08733.10 EEQ31127.1 - 3.2e-113 378.1 0.0 3.8e-113 377.8 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 MFS_1 PF07690.16 EEQ31129.1 - 1.5e-38 132.7 45.6 5.8e-38 130.7 45.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ31129.1 - 1.9e-11 43.1 9.0 2.8e-11 42.5 9.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Atg14 PF10186.9 EEQ31132.1 - 3.6e-16 59.1 0.8 3.6e-16 59.1 0.8 2.0 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EEQ31132.1 - 1.5e-07 30.6 2.6 0.0015 17.5 0.3 3.3 3 0 0 3 3 3 3 Vacuolar protein sorting 38 Mhr1 PF12829.7 EEQ31133.1 - 6.3e-27 93.5 0.0 1.3e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination PP2C PF00481.21 EEQ31134.1 - 6.1e-63 212.9 0.0 1.2e-49 169.3 0.0 3.4 2 1 0 2 2 2 2 Protein phosphatase 2C AAA_33 PF13671.6 EEQ31134.1 - 0.028 14.6 0.0 0.084 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Snf7 PF03357.21 EEQ31135.1 - 4.7e-34 117.5 16.8 4.7e-34 117.5 16.8 2.5 3 0 0 3 3 3 1 Snf7 Mis14 PF08641.12 EEQ31135.1 - 0.16 12.3 9.9 0.98 9.7 2.8 2.6 1 1 1 2 2 2 0 Kinetochore protein Mis14 like Dynamin_N PF00350.23 EEQ31136.1 - 3.9e-18 66.1 0.5 3.5e-17 63.0 0.1 2.8 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 EEQ31136.1 - 7.1e-11 42.2 0.0 1.1e-08 35.2 0.0 3.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ31136.1 - 1.1e-06 28.3 0.1 0.00065 19.3 0.1 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 EEQ31136.1 - 0.004 17.1 0.1 0.013 15.5 0.1 1.8 1 0 0 1 1 1 1 Short coiled-coil protein FeoB_N PF02421.18 EEQ31136.1 - 0.016 14.7 0.5 12 5.4 0.0 3.8 5 0 0 5 5 5 0 Ferrous iron transport protein B RnlA_toxin PF15935.5 EEQ31136.1 - 0.059 13.2 0.9 8.1 6.2 0.1 2.4 2 0 0 2 2 2 0 RNase LS, bacterial toxin TsaE PF02367.17 EEQ31136.1 - 0.061 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IIGP PF05049.13 EEQ31136.1 - 0.086 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 EEQ31136.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EEQ31136.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 EEQ31136.1 - 0.15 12.2 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NEMO PF11577.8 EEQ31136.1 - 1.1 9.3 3.8 1.1 9.3 1.9 2.0 2 0 0 2 2 1 0 NF-kappa-B essential modulator NEMO PTCB-BRCT PF12738.7 EEQ31137.1 - 1.3e-45 153.1 1.2 9.7e-24 83.1 0.3 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 EEQ31137.1 - 4.2e-30 104.0 1.0 6.7e-12 45.6 0.1 4.6 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EEQ31137.1 - 1.2e-10 41.7 0.0 0.00011 22.5 0.0 4.2 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EEQ31137.1 - 3e-05 24.2 1.6 0.25 11.6 0.0 4.3 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EEQ31137.1 - 0.12 12.2 0.0 4.8 7.1 0.0 2.7 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain PIF1 PF05970.14 EEQ31138.1 - 5.6e-61 206.7 0.1 8.6e-61 206.1 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EEQ31138.1 - 2e-24 86.4 0.0 3.8e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ31138.1 - 1.5e-10 41.6 0.0 9.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ31138.1 - 1.7e-06 28.3 0.0 5.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EEQ31138.1 - 3.9e-05 24.1 0.2 0.00012 22.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EEQ31138.1 - 4.1e-05 23.2 0.1 0.00014 21.5 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region Herpes_Helicase PF02689.14 EEQ31138.1 - 4.9e-05 21.5 0.1 0.00043 18.4 0.0 2.0 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 EEQ31138.1 - 0.00022 21.0 0.1 0.00058 19.6 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EEQ31138.1 - 0.0017 18.1 0.0 0.49 10.1 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EEQ31138.1 - 0.014 15.7 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 EEQ31138.1 - 0.027 13.9 0.0 0.073 12.5 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 EEQ31138.1 - 0.029 14.4 0.2 0.11 12.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EEQ31138.1 - 0.047 13.7 1.0 0.15 12.1 0.3 2.3 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 EEQ31138.1 - 0.049 12.9 2.5 0.05 12.8 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EEQ31138.1 - 0.055 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EEQ31138.1 - 0.055 13.9 0.0 0.53 10.7 0.0 2.7 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.22 EEQ31138.1 - 0.068 12.3 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain SH3_13 PF18335.1 EEQ31138.1 - 0.07 13.0 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain DUF5605 PF18310.1 EEQ31138.1 - 0.08 12.8 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) ATPase_2 PF01637.18 EEQ31138.1 - 0.12 12.3 1.5 0.79 9.6 1.5 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SICA_C PF12879.7 EEQ31139.1 - 0.011 15.8 6.0 4.1 7.4 0.1 3.3 2 1 1 3 3 3 0 SICA C-terminal inner membrane domain Peptidase_S32 PF05579.13 EEQ31140.1 - 0.024 13.8 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Pro_isomerase PF00160.21 EEQ31141.1 - 1.8e-41 142.0 0.0 3.4e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 EEQ31141.1 - 0.00021 21.4 0.0 0.00061 19.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 EEQ31141.1 - 0.00022 20.7 3.2 0.0018 17.7 3.2 2.3 1 1 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.15 EEQ31141.1 - 0.00051 20.2 0.0 0.0021 18.2 0.0 2.0 1 1 0 1 1 1 1 U-box domain DUF3340 PF11818.8 EEQ31141.1 - 0.017 15.3 4.2 0.017 15.3 4.2 1.6 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Pkinase PF00069.25 EEQ31142.1 - 4.9e-17 62.2 0.5 2e-15 56.9 0.1 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31142.1 - 1.1e-09 38.0 0.0 4.5e-07 29.4 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 EEQ31142.1 - 1.7e-06 27.8 0.0 3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family FolB PF02152.18 EEQ31142.1 - 0.21 12.2 0.0 7.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Dihydroneopterin aldolase YjeF_N PF03853.15 EEQ31143.1 - 1.7e-32 112.6 0.1 2.9e-32 111.9 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EEQ31143.1 - 1.2e-07 32.6 0.5 1.2e-07 32.6 0.5 2.3 2 0 0 2 2 2 1 FDF domain MDM10 PF12519.8 EEQ31144.1 - 1e-142 476.3 6.4 6e-124 414.4 4.6 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 TIM PF00121.18 EEQ31145.1 - 5.6e-90 301.0 0.6 6.3e-90 300.8 0.6 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF924 PF06041.11 EEQ31146.1 - 2.1e-51 174.6 0.4 2.6e-51 174.3 0.4 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Methyltransf_2 PF00891.18 EEQ31147.1 - 2.3e-25 89.1 0.0 3.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EEQ31147.1 - 0.0011 19.6 0.0 0.0028 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EEQ31147.1 - 0.0036 17.4 0.0 0.0068 16.5 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 EEQ31147.1 - 0.039 14.6 0.0 0.086 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ31147.1 - 0.044 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 EEQ31148.1 - 1.8e-50 171.8 0.0 2.5e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EEQ31148.1 - 9.5e-26 91.3 0.2 1.8e-25 90.4 0.2 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EEQ31148.1 - 8.8e-13 48.4 0.2 1.8e-12 47.4 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 EEQ31148.1 - 7.7e-06 25.7 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ31148.1 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ31148.1 - 0.007 17.0 0.0 0.025 15.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.11 EEQ31148.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Methyltransf_2 PF00891.18 EEQ31149.1 - 2.1e-20 72.9 0.0 3.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EEQ31149.1 - 0.00012 22.0 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 EEQ31149.1 - 0.0051 16.8 0.0 0.021 14.8 0.0 2.1 1 0 0 1 1 1 1 Dimerisation domain FA_desaturase_2 PF03405.14 EEQ31149.1 - 0.13 11.1 0.2 0.21 10.4 0.2 1.3 1 0 0 1 1 1 0 Fatty acid desaturase p450 PF00067.22 EEQ31150.1 - 2.8e-44 151.6 0.0 2.6e-36 125.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 EEQ31152.1 - 1.6e-33 116.1 67.1 4.7e-32 111.3 40.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ31152.1 - 3.6e-11 42.6 7.7 3.6e-11 42.6 7.7 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3493 PF11998.8 EEQ31152.1 - 0.27 11.4 8.5 7.3 6.8 0.9 4.9 5 0 0 5 5 5 0 Low psii accumulation1 / Rep27 NmrA PF05368.13 EEQ31153.1 - 4.4e-33 114.8 0.0 9.9e-33 113.6 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EEQ31153.1 - 5.3e-20 72.1 0.0 8e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ENOD93 PF03386.14 EEQ31153.1 - 4.5 7.2 6.3 1.9 8.4 0.2 2.7 3 0 0 3 3 3 0 Early nodulin 93 ENOD93 protein p450 PF00067.22 EEQ31154.1 - 4.8e-23 81.6 0.0 1.4e-22 80.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 RL10P_insert PF17777.1 EEQ31155.1 - 2.1e-22 78.9 0.0 4.8e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EEQ31155.1 - 3e-18 65.8 0.0 5.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.8 EEQ31156.1 - 9.2e-28 96.7 1.0 2.2e-27 95.5 1.0 1.7 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EEQ31156.1 - 1.2e-16 60.3 0.0 2.5e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ31156.1 - 0.0002 21.4 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 EEQ31157.1 - 1.5e-16 60.0 0.3 2.3e-16 59.4 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain zinc_ribbon_10 PF10058.9 EEQ31158.1 - 0.0014 18.3 0.2 0.0029 17.3 0.2 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein FYVE PF01363.21 EEQ31158.1 - 0.0058 16.7 6.4 0.01 16.0 6.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_5 PF14634.6 EEQ31158.1 - 0.014 15.3 5.9 0.026 14.5 5.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EEQ31158.1 - 0.018 15.4 3.1 0.018 15.4 3.1 2.0 2 0 0 2 2 2 0 Ring finger domain PhnA_Zn_Ribbon PF08274.12 EEQ31158.1 - 0.034 14.1 0.5 1 9.4 0.1 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-C3HC4_2 PF13923.6 EEQ31158.1 - 0.036 13.9 2.9 0.046 13.6 0.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UBP PF02148.19 EEQ31158.1 - 0.041 14.2 5.9 0.089 13.1 5.9 1.6 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_UBOX PF13445.6 EEQ31158.1 - 0.041 13.9 2.6 0.091 12.8 2.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EEQ31158.1 - 0.11 12.4 6.1 0.28 11.1 6.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.11 EEQ31158.1 - 0.13 12.2 2.2 0.31 11.0 2.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Prok-RING_4 PF14447.6 EEQ31158.1 - 0.25 11.2 5.4 4.6 7.2 5.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 EEQ31158.1 - 0.35 11.1 8.6 0.35 11.1 4.3 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 EEQ31158.1 - 0.68 10.1 4.0 1 9.6 0.7 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EEQ31158.1 - 0.74 9.7 6.7 11 6.0 7.8 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 EEQ31158.1 - 2.2 8.5 7.7 14 5.9 7.7 2.1 1 1 0 1 1 1 0 B-box zinc finger Prp19 PF08606.11 EEQ31159.1 - 3.8e-33 113.3 1.2 7.1e-33 112.4 1.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EEQ31159.1 - 2.4e-14 53.4 0.1 1.1e-07 32.1 0.0 4.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ31159.1 - 4.7e-09 36.7 9.9 1.9e-05 25.3 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EEQ31159.1 - 2.2e-07 30.3 0.5 0.0031 16.6 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 EEQ31159.1 - 6.4e-07 29.4 0.0 0.025 14.5 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EEQ31159.1 - 2.9e-05 23.6 0.1 0.053 12.8 0.0 2.5 1 1 2 3 3 3 2 WD40-like domain V_ATPase_I_N PF18670.1 EEQ31159.1 - 0.00046 20.5 0.1 0.001 19.4 0.1 1.5 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain zf-Nse PF11789.8 EEQ31159.1 - 0.017 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cytochrom_D1 PF02239.16 EEQ31159.1 - 0.018 13.6 0.5 1.5 7.3 0.0 2.3 1 1 0 2 2 2 0 Cytochrome D1 heme domain HPS3_N PF14761.6 EEQ31159.1 - 0.024 14.2 0.0 14 5.1 0.0 2.9 1 1 2 3 3 3 0 Hermansky-Pudlak syndrome 3 Ge1_WD40 PF16529.5 EEQ31159.1 - 0.042 12.8 0.1 0.11 11.5 0.1 1.7 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 EEQ31159.1 - 0.046 13.0 0.1 0.56 9.4 0.0 1.8 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Frtz PF11768.8 EEQ31159.1 - 0.13 10.5 0.0 0.42 8.9 0.0 1.6 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4604 PF15377.6 EEQ31160.1 - 1.8e-21 77.3 14.4 2.1e-21 77.1 14.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) GTP_EFTU PF00009.27 EEQ31161.1 - 6.6e-57 192.2 0.0 1.1e-56 191.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EEQ31161.1 - 3.5e-15 55.8 0.0 8.5e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEQ31161.1 - 6.7e-08 32.8 0.0 2.4e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EEQ31161.1 - 8e-07 29.1 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EEQ31161.1 - 0.00026 20.8 0.0 0.0029 17.4 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EEQ31161.1 - 0.081 13.0 0.0 0.27 11.4 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase EXOSC1 PF10447.9 EEQ31162.1 - 7e-28 97.4 4.9 1.2e-27 96.6 4.9 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EEQ31162.1 - 2.7e-11 43.0 0.2 5.1e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Arm PF00514.23 EEQ31163.1 - 1.2e-69 228.4 28.2 3.6e-11 42.7 0.1 11.3 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EEQ31163.1 - 2e-17 63.3 19.2 1.4e-05 25.5 0.3 7.8 6 3 3 9 9 8 5 HEAT-like repeat HEAT_2 PF13646.6 EEQ31163.1 - 3.8e-15 56.0 12.2 0.00016 22.0 0.0 7.0 2 2 4 6 6 6 3 HEAT repeats HEAT PF02985.22 EEQ31163.1 - 8.6e-15 53.6 15.7 0.24 11.8 0.2 9.0 10 0 0 10 10 10 4 HEAT repeat Adaptin_N PF01602.20 EEQ31163.1 - 5.2e-14 51.7 6.6 1.2e-08 34.0 0.2 2.7 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 EEQ31163.1 - 4.4e-09 35.1 0.4 1.6e-08 33.2 0.1 1.8 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 EEQ31163.1 - 6.2e-09 35.7 5.0 2.6e-05 23.8 2.0 2.5 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 EEQ31163.1 - 3.9e-08 32.9 1.2 0.00055 19.3 0.8 2.7 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 EEQ31163.1 - 0.00054 20.0 5.5 0.044 13.8 0.5 4.4 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 EEQ31163.1 - 0.00056 19.4 8.3 0.31 10.4 0.0 4.6 1 1 3 5 5 5 1 Family of unknown function (DUF5578) HEAT_PBS PF03130.16 EEQ31163.1 - 0.00083 19.8 7.9 1.2 10.0 0.5 6.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 EEQ31163.1 - 0.0012 19.0 1.2 28 4.9 0.0 4.9 2 1 4 6 6 6 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 EEQ31163.1 - 0.0013 18.7 2.6 1.7 8.7 0.0 4.6 4 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 EEQ31163.1 - 0.003 17.5 6.5 2.2 8.2 0.0 4.2 2 1 2 4 4 4 1 Domain of unknown function (DUF3361) UNC45-central PF11701.8 EEQ31163.1 - 0.012 15.6 1.5 1.3 9.0 0.1 3.1 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 EEQ31163.1 - 0.033 14.8 0.1 0.67 10.6 0.1 3.0 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Pkinase PF00069.25 EEQ31164.1 - 1.7e-22 80.0 0.0 2.9e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31164.1 - 4.2e-07 29.5 0.0 7.1e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 EEQ31165.1 - 2.1e-14 53.6 0.0 4.6e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EEQ31165.1 - 5.4e-10 38.8 3.6 1.1e-09 37.9 3.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EEQ31165.1 - 1.5e-06 28.4 8.7 2.9e-06 27.5 8.7 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EEQ31165.1 - 0.00026 21.3 0.0 0.00059 20.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 EEQ31165.1 - 0.0019 18.1 6.6 0.0037 17.2 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING-like PF08746.11 EEQ31165.1 - 0.019 15.3 5.7 0.049 14.0 5.7 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 EEQ31165.1 - 0.025 14.4 7.7 0.05 13.5 7.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ31165.1 - 0.06 13.2 8.6 0.12 12.2 8.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EEQ31165.1 - 0.063 13.3 2.5 0.16 12.1 2.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 EEQ31165.1 - 0.15 11.9 5.7 0.31 10.9 5.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.7 EEQ31165.1 - 0.67 10.3 8.1 2.1 8.7 8.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EEQ31165.1 - 4.6 6.9 8.4 9.7 5.9 8.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Bestrophin PF01062.21 EEQ31166.1 - 4e-58 197.1 0.0 5e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel AAA_lid_2 PF17863.1 EEQ31168.1 - 0.013 15.4 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA lid domain Fungal_lectin_2 PF18647.1 EEQ31169.1 - 9.7e-43 144.8 2.2 2.8e-42 143.3 2.2 1.8 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 EEQ31169.1 - 1.3e-11 45.3 0.3 1.1e-09 38.9 0.0 2.3 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EEQ31169.1 - 1.9e-10 41.1 0.0 3.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Astacin PF01400.24 EEQ31170.1 - 0.14 11.7 0.9 2.2 7.8 0.0 2.7 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) Glyco_hydro_18 PF00704.28 EEQ31171.1 - 1e-68 232.4 0.1 1.3e-68 232.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EEQ31171.1 - 8e-09 35.8 8.6 8e-09 35.8 8.6 2.6 2 1 0 2 2 2 2 Chitin recognition protein Nse4-Nse3_bdg PF15412.6 EEQ31171.1 - 0.099 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE LysM PF01476.20 EEQ31172.1 - 3e-24 84.8 0.1 1.8e-06 27.9 0.0 5.9 6 0 0 6 6 6 5 LysM domain Vps16_N PF04841.13 EEQ31174.1 - 2.5e-97 326.2 0.0 6.3e-97 324.9 0.0 1.6 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.12 EEQ31174.1 - 7.8e-90 301.2 0.1 1.2e-89 300.5 0.1 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EEQ31174.1 - 0.00034 20.9 0.0 0.013 15.8 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Alb1 PF09135.11 EEQ31175.1 - 1.3e-30 106.3 10.5 2e-30 105.7 10.5 1.3 1 0 0 1 1 1 1 Alb1 UCH PF00443.29 EEQ31176.1 - 7.6e-30 104.3 0.0 4.2e-29 101.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ31176.1 - 1e-07 31.9 0.1 1e-05 25.3 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_9 PF14658.6 EEQ31177.1 - 0.00046 20.5 0.0 0.51 10.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 EEQ31177.1 - 0.079 12.9 0.0 8.3 6.6 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain T2SSG PF08334.11 EEQ31177.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Peptidase_C97 PF05903.14 EEQ31178.1 - 3e-40 137.5 0.0 4.1e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 EEQ31178.1 - 5.1e-15 55.3 0.0 7.7e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EEQ31178.1 - 2.7e-05 24.1 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EEQ31178.1 - 0.00018 21.9 0.2 0.00085 19.7 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2847 PF11009.8 EEQ31178.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) OST3_OST6 PF04756.13 EEQ31178.1 - 0.0041 16.5 0.0 0.0057 16.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EEQ31178.1 - 0.0086 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EEQ31178.1 - 0.023 14.4 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.6 EEQ31178.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 EEQ31178.1 - 0.18 12.0 0.4 1 9.5 0.3 1.9 1 1 1 2 2 2 0 Thioredoxin IBR PF01485.21 EEQ31179.1 - 2.4e-06 27.6 8.4 2.4e-06 27.6 8.4 2.2 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain Cluap1 PF10234.9 EEQ31179.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 AMP-binding PF00501.28 EEQ31180.1 - 3.1e-61 207.2 0.2 5e-61 206.6 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EEQ31180.1 - 4.3e-39 134.5 0.0 6.7e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Thioesterase PF00975.20 EEQ31180.1 - 6.5e-16 59.2 0.0 1.1e-14 55.2 0.0 2.6 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EEQ31180.1 - 5.9e-09 36.2 0.0 1.2e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 EEQ31180.1 - 3.2e-08 34.4 1.7 2.5e-07 31.5 0.2 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family AMP-binding_C PF13193.6 EEQ31180.1 - 1.4e-05 26.0 0.1 4.7e-05 24.3 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_3 PF07859.13 EEQ31180.1 - 0.00041 20.3 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EEQ31180.1 - 0.00049 19.8 0.0 0.00092 18.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PTR2 PF00854.21 EEQ31181.1 - 1.5e-81 274.3 5.7 4.3e-81 272.8 5.7 1.7 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 EEQ31183.1 - 4.1e-28 98.3 31.6 1.3e-15 57.2 9.2 2.9 1 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ31183.1 - 9.9e-10 37.8 8.4 9.9e-10 37.8 8.4 3.0 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EEQ31183.1 - 5.2e-06 26.0 4.3 9.3e-06 25.2 1.2 2.4 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2583 PF10762.9 EEQ31183.1 - 0.041 14.3 2.9 0.87 10.0 1.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) SNF2_N PF00176.23 EEQ31186.1 - 1.4e-27 96.4 0.1 6.1e-27 94.3 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 EEQ31186.1 - 3.6e-08 33.6 0.0 6.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ31186.1 - 1.8e-07 31.5 0.0 4.5e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PIF1 PF05970.14 EEQ31187.1 - 9.2e-29 100.7 0.0 5.2e-25 88.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 EEQ31187.1 - 6.9e-24 85.1 0.3 1.3e-23 84.2 0.3 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EEQ31187.1 - 1.4e-13 51.0 0.0 2.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ31187.1 - 8.3e-08 32.7 0.0 2.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EEQ31187.1 - 0.00049 18.2 0.0 0.00083 17.4 0.0 1.3 1 0 0 1 1 1 1 Helicase KAP_NTPase PF07693.14 EEQ31187.1 - 0.0074 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain UvrD_C_2 PF13538.6 EEQ31187.1 - 0.012 15.4 0.0 0.039 13.8 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Torsin PF06309.11 EEQ31187.1 - 0.021 14.9 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 Torsin SH3_13 PF18335.1 EEQ31187.1 - 0.053 13.4 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Fungal_trans PF04082.18 EEQ31188.1 - 8.2e-06 25.0 0.2 2e-05 23.8 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAAA-beta PF15508.6 EEQ31189.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HET PF06985.11 EEQ31190.1 - 1.2e-09 38.7 2.8 7.3e-07 29.6 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.17 EEQ31190.1 - 0.00016 21.4 14.0 0.00026 20.7 7.8 2.3 2 0 0 2 2 2 2 Zinc finger, ZZ type C1_2 PF03107.16 EEQ31190.1 - 0.00068 19.9 3.4 0.00068 19.9 3.4 2.3 2 0 0 2 2 2 1 C1 domain Phosphoesterase PF04185.14 EEQ31191.1 - 1.2e-60 205.6 3.3 5.7e-60 203.4 3.3 1.9 1 1 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.15 EEQ31192.1 - 3.6e-17 62.5 0.0 7.3e-16 58.2 0.0 2.6 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EEQ31192.1 - 3e-13 50.2 0.0 1.4e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase WW PF00397.26 EEQ31193.1 - 4e-06 26.8 0.5 8.9e-06 25.7 0.5 1.6 1 0 0 1 1 1 1 WW domain Methyltransf_23 PF13489.6 EEQ31194.1 - 5.3e-05 23.1 0.0 7.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ31194.1 - 0.00011 22.8 0.0 0.00031 21.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ31194.1 - 0.00037 21.1 0.0 0.00094 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ31194.1 - 0.012 15.5 0.0 0.082 12.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ31194.1 - 0.015 16.1 0.0 0.058 14.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EEQ31194.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.14 EEQ31194.1 - 0.092 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Opy2 PF09463.10 EEQ31195.1 - 4.6e-07 30.0 19.3 4.6e-07 30.0 19.3 1.8 2 0 0 2 2 2 1 Opy2 protein EphA2_TM PF14575.6 EEQ31195.1 - 0.099 13.5 0.0 0.21 12.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RSN1_TM PF13967.6 EEQ31195.1 - 0.15 11.8 0.1 0.59 9.9 0.0 1.8 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport AMP-binding PF00501.28 EEQ31196.1 - 1.3e-43 149.2 0.0 1.9e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ31196.1 - 0.00026 21.9 0.0 0.00045 21.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Chitin_synth_1 PF01644.17 EEQ31197.1 - 6.8e-69 231.0 0.0 9.9e-69 230.5 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EEQ31197.1 - 2.7e-28 97.7 0.0 5.1e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EEQ31197.1 - 1.2e-23 83.5 0.0 7.9e-19 67.7 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EEQ31197.1 - 4.2e-09 36.6 0.3 4.2e-09 36.6 0.3 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Psu PF07455.11 EEQ31197.1 - 0.037 13.6 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) UQ_con PF00179.26 EEQ31198.1 - 1.1e-35 122.3 0.0 1.4e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ31198.1 - 0.062 13.0 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B TAF8_C PF10406.9 EEQ31199.1 - 5.2e-21 74.9 0.6 1.7e-20 73.3 0.6 2.0 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EEQ31199.1 - 1.7e-06 28.0 0.0 4e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated Mitochondr_Som1 PF11093.8 EEQ31200.1 - 8.8e-21 73.7 0.0 1e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Rad51 PF08423.11 EEQ31201.1 - 5.2e-05 22.6 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 2 Rad51 Laminin_B PF00052.18 EEQ31201.1 - 0.1 12.5 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Laminin B (Domain IV) PALP PF00291.25 EEQ31202.1 - 1.2e-64 218.6 0.0 1.5e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EEQ31202.1 - 0.0089 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family IlvN PF07991.12 EEQ31203.1 - 6.9e-46 155.8 0.0 1.1e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EEQ31203.1 - 3.2e-41 141.0 0.1 5.8e-41 140.2 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 EEQ31203.1 - 0.025 14.8 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EEQ31203.1 - 0.1 13.2 0.1 0.32 11.6 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2OG-FeII_Oxy_2 PF13532.6 EEQ31204.1 - 1.5e-26 93.8 0.0 3.2e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EEQ31204.1 - 2.6e-21 76.6 0.0 7.4e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family GST_N_2 PF13409.6 EEQ31204.1 - 0.11 12.8 0.0 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain ECH_1 PF00378.20 EEQ31205.1 - 4.2e-41 140.9 0.0 6.8e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EEQ31205.1 - 4.3e-29 102.1 0.0 1.3e-28 100.5 0.0 1.6 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase CBM_2 PF00553.19 EEQ31205.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Cellulose binding domain Tfb5 PF06331.12 EEQ31206.1 - 2.4e-21 75.5 0.1 2.6e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Trypsin_2 PF13365.6 EEQ31207.1 - 0.00028 21.8 0.1 0.0012 19.8 0.1 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 EEQ31207.1 - 0.00053 18.6 0.1 0.026 13.0 0.2 2.2 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S46 PF10459.9 EEQ31207.1 - 0.045 12.4 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S32 PF05579.13 EEQ31207.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 FAD_binding_4 PF01565.23 EEQ31208.1 - 3.1e-25 88.5 6.2 4.8e-25 87.9 6.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EEQ31208.1 - 6.7e-08 32.5 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 EEQ31209.1 - 0.00076 18.3 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 EEQ31210.1 - 2.6e-12 47.3 0.0 4.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ31210.1 - 6.7e-09 36.3 0.0 1.1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ31210.1 - 1.2e-08 35.6 0.0 1.4e-07 32.1 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ31210.1 - 4.8e-06 26.4 0.0 1e-05 25.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EEQ31210.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 EEQ31210.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 EEQ31210.1 - 0.035 13.2 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase DUF3678 PF12435.8 EEQ31210.1 - 0.37 10.2 3.4 0.94 8.9 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) APH PF01636.23 EEQ31211.1 - 2.1e-11 44.2 0.0 6.2e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ31211.1 - 3e-05 23.7 0.0 4.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EEQ31211.1 - 0.016 14.8 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Gmx_para_CXXCG PF09535.10 EEQ31211.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) Pkinase PF00069.25 EEQ31211.1 - 0.15 11.4 0.0 0.53 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain GTP_EFTU PF00009.27 EEQ31212.1 - 1.8e-51 174.5 0.0 3.1e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EEQ31212.1 - 1.9e-38 130.9 2.8 3.4e-38 130.1 2.8 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EEQ31212.1 - 1.4e-20 73.1 0.0 2.6e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.22 EEQ31212.1 - 1.6e-05 24.5 0.0 0.0001 21.9 0.0 2.1 2 0 0 2 2 2 1 Ras family GTP_EFTU_D2 PF03144.25 EEQ31212.1 - 3.8e-05 24.0 0.6 8.2e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ31212.1 - 4.8e-05 23.4 0.0 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EEQ31212.1 - 0.0007 19.6 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EEQ31212.1 - 0.005 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EEQ31212.1 - 0.014 14.8 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Snurportin1 PF11538.8 EEQ31212.1 - 0.034 14.4 0.7 0.089 13.0 0.7 1.7 1 0 0 1 1 1 0 Snurportin1 MMR_HSR1_Xtn PF16897.5 EEQ31212.1 - 0.045 13.8 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Roc PF08477.13 EEQ31212.1 - 0.14 12.3 0.0 0.73 10.1 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HORMA PF02301.18 EEQ31213.1 - 1.8e-22 80.0 0.2 1.9e-21 76.6 0.2 1.9 1 1 0 1 1 1 1 HORMA domain DUF2660 PF10859.8 EEQ31213.1 - 0.02 15.4 0.3 0.067 13.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) bacHORMA_2 PF18173.1 EEQ31213.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial HORMA domain 2 Sec1 PF00995.23 EEQ31215.1 - 1.3e-127 427.4 0.0 1.5e-127 427.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1043 PF06295.12 EEQ31215.1 - 0.26 11.3 1.5 0.58 10.2 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) FHA PF00498.26 EEQ31217.1 - 4.2e-12 46.2 0.0 7.9e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain TPR_1 PF00515.28 EEQ31218.1 - 4.9e-37 124.3 33.2 4.9e-06 26.1 0.1 10.7 10 1 1 11 11 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ31218.1 - 2.9e-35 117.5 32.4 7.8e-05 22.5 0.1 11.2 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ31218.1 - 2.2e-18 64.9 26.3 0.0003 20.7 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ31218.1 - 1.2e-17 64.2 19.7 0.0037 17.9 0.1 7.0 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ31218.1 - 3.4e-17 61.8 29.2 8.9e-07 28.5 0.1 8.9 7 2 3 10 10 10 5 TPR repeat TPR_12 PF13424.6 EEQ31218.1 - 2.3e-14 53.4 32.0 0.00024 21.3 2.7 7.9 4 3 4 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ31218.1 - 7e-14 51.1 18.0 0.16 12.4 0.1 9.1 8 2 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ31218.1 - 1.5e-12 47.9 22.6 6.3e-06 26.6 2.7 7.3 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ31218.1 - 3.6e-12 45.4 19.2 0.0095 15.9 0.6 8.9 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ31218.1 - 1.2e-10 41.4 13.5 0.00059 19.9 1.7 6.5 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ31218.1 - 4.7e-09 36.3 22.4 0.037 14.9 1.1 9.3 4 4 7 11 11 10 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ31218.1 - 7.8e-07 28.8 6.2 0.01 15.3 2.3 3.5 2 1 2 4 4 4 2 MalT-like TPR region ANAPC3 PF12895.7 EEQ31218.1 - 1.1e-06 28.7 15.6 0.085 13.1 0.4 5.6 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EEQ31218.1 - 4.2e-06 26.5 25.3 0.051 13.5 1.0 8.5 10 0 0 10 10 9 3 Tetratricopeptide repeat MAS20 PF02064.15 EEQ31218.1 - 0.0028 17.7 5.8 0.035 14.2 0.5 3.8 3 1 1 4 4 4 1 MAS20 protein import receptor TAF1_subA PF14929.6 EEQ31218.1 - 0.0033 16.9 0.8 0.0088 15.5 0.4 1.8 2 1 0 2 2 2 1 TAF RNA Polymerase I subunit A DUF3856 PF12968.7 EEQ31218.1 - 0.0066 16.5 4.9 7.1 6.7 0.0 4.8 3 2 1 4 4 4 1 Domain of Unknown Function (DUF3856) Sel1 PF08238.12 EEQ31218.1 - 0.0069 17.0 4.6 0.9 10.3 0.1 4.3 4 0 0 4 4 3 1 Sel1 repeat SHNi-TPR PF10516.9 EEQ31218.1 - 0.0072 15.8 16.7 0.18 11.3 0.0 7.1 8 0 0 8 8 8 1 SHNi-TPR AP3D1 PF06375.11 EEQ31218.1 - 0.0076 16.5 2.4 0.014 15.6 2.4 1.4 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 TPR_4 PF07721.14 EEQ31218.1 - 0.046 14.4 4.2 1.7e+02 3.3 0.2 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EEQ31218.1 - 0.084 13.0 12.9 8.9 6.5 0.3 5.9 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain FAT PF02259.23 EEQ31218.1 - 0.28 10.4 3.6 8.3 5.5 0.3 3.0 3 0 0 3 3 3 0 FAT domain BTAD PF03704.17 EEQ31218.1 - 0.59 10.6 7.4 11 6.4 0.4 4.2 4 1 0 4 4 4 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 EEQ31218.1 - 3.1 8.6 24.7 9.5 7.1 0.9 7.9 10 0 0 10 10 7 0 Tetratricopeptide repeat Aminotran_4 PF01063.19 EEQ31219.1 - 1.3e-33 116.7 0.0 1.6e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Nramp PF01566.18 EEQ31220.1 - 1.1e-87 294.4 23.4 9.5e-87 291.3 23.4 2.0 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Peptidase_S8 PF00082.22 EEQ31221.1 - 8.7e-30 104.0 17.6 2.2e-29 102.7 17.6 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ31221.1 - 3.1e-15 56.6 0.5 5e-15 55.9 0.5 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3553 PF12073.8 EEQ31221.1 - 0.084 12.6 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Sugar_tr PF00083.24 EEQ31223.1 - 3.5e-84 283.3 22.1 4e-84 283.1 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ31223.1 - 1.1e-15 57.5 31.8 3.8e-15 55.7 23.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily CrgA PF06781.12 EEQ31223.1 - 0.86 9.7 4.8 8.9 6.5 0.0 3.7 4 0 0 4 4 4 0 Cell division protein CrgA Kinesin PF00225.23 EEQ31224.1 - 4e-99 331.7 1.2 4e-99 331.7 1.2 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ31224.1 - 2.9e-50 170.1 0.1 2.9e-50 170.1 0.1 2.5 2 1 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 EEQ31224.1 - 0.031 14.6 1.3 0.76 10.1 0.1 3.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EEQ31224.1 - 0.13 12.7 0.0 0.13 12.7 0.0 3.3 2 1 0 2 2 2 0 AAA ATPase domain DUF1899 PF08953.11 EEQ31225.1 - 8.3e-33 112.1 0.0 2.1e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EEQ31225.1 - 1.5e-20 72.8 0.1 3.9e-20 71.5 0.1 1.8 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EEQ31225.1 - 4.8e-14 52.5 3.4 0.00093 20.0 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ31225.1 - 8.1e-06 26.1 0.0 0.0054 17.0 0.1 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ31225.1 - 0.025 14.5 0.0 0.59 10.0 0.1 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EEQ31225.1 - 0.076 11.6 0.2 0.17 10.5 0.1 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 FAM76 PF16046.5 EEQ31225.1 - 0.2 11.0 0.2 0.27 10.5 0.2 1.2 1 0 0 1 1 1 0 FAM76 protein COG2 PF06148.11 EEQ31225.1 - 0.24 11.5 0.6 0.42 10.7 0.6 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C3HC4_3 PF13920.6 EEQ31226.1 - 0.0018 18.1 10.1 0.0031 17.3 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Transposase_21 PF02992.14 EEQ31226.1 - 0.19 11.0 0.1 0.35 10.1 0.1 1.3 1 0 0 1 1 1 0 Transposase family tnp2 CBFD_NFYB_HMF PF00808.23 EEQ31228.1 - 3.6e-14 52.8 1.0 5.7e-14 52.2 1.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.13 EEQ31228.1 - 2.5e-05 24.5 30.1 3.5e-05 24.0 30.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 EEQ31228.1 - 0.00014 22.2 0.2 0.00014 22.2 0.2 3.2 4 0 0 4 4 4 1 Core histone H2A/H2B/H3/H4 EMC3_TMCO1 PF01956.16 EEQ31228.1 - 0.96 9.2 4.2 1.7 8.4 4.2 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4407 PF14362.6 EEQ31228.1 - 2.6 7.3 6.5 3.1 7.1 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.9 EEQ31228.1 - 4.2 5.5 31.6 5.5 5.1 31.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 EEQ31228.1 - 9.6 5.0 18.4 7.7 5.4 17.6 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BTB PF00651.31 EEQ31229.1 - 0.00075 19.7 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RAI16-like PF10257.9 EEQ31230.1 - 1.5e-72 244.5 0.0 2.2e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Lipase_3 PF01764.25 EEQ31231.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Inhibitor_I9 PF05922.16 EEQ31231.1 - 0.78 10.4 6.5 0.99 10.1 3.5 2.2 2 0 0 2 2 2 0 Peptidase inhibitor I9 ILVD_EDD PF00920.21 EEQ31232.1 - 1e-210 700.8 0.1 1.2e-210 700.5 0.1 1.1 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 EEQ31232.1 - 0.13 12.5 0.0 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain Tox-ART-HYD1 PF15633.6 EEQ31233.1 - 0.13 12.9 0.0 0.24 12.1 0.0 1.3 1 0 0 1 1 1 0 HYD1 signature containing ADP-ribosyltransferase APH PF01636.23 EEQ31236.1 - 3.8e-14 53.2 0.0 2.1e-13 50.7 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EEQ31237.1 - 1.2e-44 152.6 0.0 1.6e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31237.1 - 8.4e-29 100.6 0.0 1.1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ31237.1 - 0.0094 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEQ31237.1 - 0.019 14.3 0.1 0.22 10.8 0.1 2.4 2 1 0 2 2 2 0 Kinase-like Tim17 PF02466.19 EEQ31239.1 - 9.3e-28 96.8 4.0 1.2e-27 96.4 4.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.9 EEQ31240.1 - 5.5e-59 199.7 1.2 1.3e-58 198.4 1.2 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EEQ31240.1 - 0.081 13.2 0.1 2.8 8.4 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat DUF4381 PF14316.6 EEQ31241.1 - 0.0091 16.3 1.6 0.022 15.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) PAP_PilO PF06864.12 EEQ31241.1 - 0.018 13.9 0.4 0.018 13.9 0.4 1.4 2 0 0 2 2 2 0 Pilin accessory protein (PilO) Ctr PF04145.15 EEQ31241.1 - 0.087 13.4 1.3 0.22 12.1 1.3 1.7 1 1 0 1 1 1 0 Ctr copper transporter family PX PF00787.24 EEQ31242.1 - 9.4e-19 67.5 0.0 3.1e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EEQ31242.1 - 4.9e-08 32.8 4.8 0.0022 17.6 0.9 2.1 2 0 0 2 2 2 2 Vps5 C terminal like UCH PF00443.29 EEQ31243.1 - 9.7e-67 225.2 0.0 1.5e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EEQ31243.1 - 9.2e-13 48.6 0.0 2.7e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EEQ31243.1 - 7.9e-10 38.8 0.0 0.0026 17.4 0.1 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EEQ31243.1 - 0.00046 19.9 0.0 0.0042 16.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal ubiquitin PF00240.23 EEQ31243.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family ABC_tran PF00005.27 EEQ31245.1 - 3.7e-47 160.3 0.1 4.4e-23 82.3 0.0 3.8 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 EEQ31245.1 - 6.9e-31 106.1 1.1 3.4e-30 103.9 1.1 2.3 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 EEQ31245.1 - 2.7e-17 63.5 1.2 0.0017 18.3 0.1 5.1 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ31245.1 - 1.2e-16 60.8 0.0 1.6e-06 27.7 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEQ31245.1 - 1.9e-09 38.3 3.6 0.00019 22.0 0.2 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EEQ31245.1 - 8.3e-09 35.1 0.1 0.0041 16.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ31245.1 - 2.8e-08 33.8 0.0 0.00014 21.8 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EEQ31245.1 - 1e-06 29.1 0.0 0.016 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EEQ31245.1 - 1.1e-06 28.7 0.0 0.0057 16.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ31245.1 - 1.3e-06 28.9 1.7 0.27 11.6 0.0 4.3 5 0 0 5 5 3 2 AAA ATPase domain AAA PF00004.29 EEQ31245.1 - 1.6e-06 28.6 0.4 0.19 12.2 0.0 5.2 6 0 0 6 6 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EEQ31245.1 - 6.3e-06 26.8 0.1 0.14 12.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EEQ31245.1 - 8.6e-06 26.1 0.1 0.14 12.4 0.0 3.6 4 0 0 4 4 2 2 AAA domain PduV-EutP PF10662.9 EEQ31245.1 - 4e-05 23.4 0.0 0.075 12.8 0.0 3.1 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 EEQ31245.1 - 4.4e-05 22.6 0.1 0.18 10.7 0.1 2.7 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EEQ31245.1 - 5.3e-05 23.4 0.1 0.25 11.4 0.0 3.1 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 EEQ31245.1 - 9.5e-05 22.4 0.0 0.083 12.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 EEQ31245.1 - 9.8e-05 22.2 0.1 0.91 9.2 0.0 3.4 3 1 1 4 4 4 2 AAA ATPase domain Dynamin_N PF00350.23 EEQ31245.1 - 0.00013 22.0 0.1 0.0065 16.5 0.0 2.8 2 1 0 2 2 2 1 Dynamin family RNA_helicase PF00910.22 EEQ31245.1 - 0.00016 22.0 0.0 0.76 10.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 EEQ31245.1 - 0.00021 21.5 0.0 0.61 10.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EEQ31245.1 - 0.00032 20.3 0.0 0.23 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EEQ31245.1 - 0.00075 19.3 0.0 1.2 8.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 EEQ31245.1 - 0.0012 18.9 0.0 3.4 7.7 0.0 3.3 3 1 0 3 3 2 1 AAA domain G-alpha PF00503.20 EEQ31245.1 - 0.0014 17.9 0.0 1.8 7.6 0.0 2.9 3 0 0 3 3 3 1 G-protein alpha subunit AAA_30 PF13604.6 EEQ31245.1 - 0.0016 18.2 0.0 2.3 7.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 EEQ31245.1 - 0.0017 17.6 0.8 0.14 11.3 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain SbcCD_C PF13558.6 EEQ31245.1 - 0.002 18.3 0.0 1.8 8.9 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EEQ31245.1 - 0.0051 17.0 0.0 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EEQ31245.1 - 0.0071 16.2 0.0 3.9 7.2 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EEQ31245.1 - 0.0097 15.5 0.1 8.6 5.9 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_PrkA PF08298.11 EEQ31245.1 - 0.012 14.6 0.0 18 4.1 0.0 3.1 3 0 0 3 3 3 0 PrkA AAA domain Rad17 PF03215.15 EEQ31245.1 - 0.012 15.5 0.0 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain CLP1_P PF16575.5 EEQ31245.1 - 0.017 14.9 0.0 1.4 8.6 0.0 2.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MukB PF04310.12 EEQ31245.1 - 0.019 14.8 0.1 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal Cytidylate_kin PF02224.18 EEQ31245.1 - 0.019 14.7 0.0 3.9 7.2 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase ATPase_2 PF01637.18 EEQ31245.1 - 0.022 14.7 0.0 3.2 7.6 0.0 3.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EEQ31245.1 - 0.023 14.4 0.0 13 5.5 0.0 3.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 EEQ31245.1 - 0.024 14.1 0.0 4.3 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 EEQ31245.1 - 0.025 14.3 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 EEQ31245.1 - 0.027 14.5 0.0 17 5.4 0.0 3.4 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EEQ31245.1 - 0.036 13.5 0.5 3.2 7.1 0.0 3.3 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 EEQ31245.1 - 0.039 13.9 0.0 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 EEQ31245.1 - 0.06 12.9 0.0 4.8 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EEQ31245.1 - 0.075 12.3 0.3 3.5 6.8 0.0 2.9 3 0 0 3 3 3 0 Septin DUF815 PF05673.13 EEQ31245.1 - 0.076 12.2 0.0 11 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF3437 PF11919.8 EEQ31245.1 - 0.16 11.9 0.3 1.3 8.9 0.1 2.8 2 1 1 3 3 1 0 Domain of unknown function (DUF3437) Mu-like_Pro PF10123.9 EEQ31245.1 - 0.17 11.4 10.1 0.43 10.1 10.1 1.8 1 0 0 1 1 1 0 Mu-like prophage I protein HEAT PF02985.22 EEQ31245.1 - 0.22 11.9 1.2 21 5.7 0.0 3.8 3 0 0 3 3 2 0 HEAT repeat HEAT_EZ PF13513.6 EEQ31245.1 - 2.5 8.7 6.8 15 6.2 0.0 4.5 5 0 0 5 5 3 0 HEAT-like repeat AAA_13 PF13166.6 EEQ31245.1 - 7.7 5.0 10.8 2.9 6.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain TPR_7 PF13176.6 EEQ31246.1 - 0.00077 19.3 1.3 0.34 11.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ31246.1 - 0.0012 18.5 7.8 0.038 13.8 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ31246.1 - 0.0024 17.5 0.0 0.0083 15.8 0.0 2.0 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.6 EEQ31246.1 - 0.004 17.6 5.4 12 6.5 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ31246.1 - 0.011 16.1 0.1 3.7 8.1 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ31246.1 - 0.024 15.3 12.4 0.23 12.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ31246.1 - 0.057 13.6 11.3 1.7 8.8 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ31246.1 - 0.058 13.5 0.0 0.058 13.5 0.0 5.3 6 1 0 6 6 6 0 Tetratricopeptide repeat Oxidored_q6 PF01058.22 EEQ31247.1 - 2.7e-23 82.2 0.0 3.5e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF1275 PF06912.11 EEQ31248.1 - 6.6e-25 88.2 9.4 6.6e-25 88.2 9.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1275) TraT PF05818.12 EEQ31249.1 - 0.0019 17.9 1.7 0.0019 17.9 1.7 1.9 2 0 0 2 2 2 1 Enterobacterial TraT complement resistance protein Rick_17kDa_Anti PF05433.15 EEQ31249.1 - 0.028 14.3 26.9 0.067 13.1 26.9 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EEQ31249.1 - 0.12 12.4 23.3 0.32 11.0 23.3 1.8 1 0 0 1 1 1 0 Glycine zipper AP3D1 PF06375.11 EEQ31249.1 - 5.5 7.2 18.0 0.076 13.2 10.1 1.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Ank_4 PF13637.6 EEQ31250.1 - 3.1e-10 40.4 0.2 4.6e-08 33.4 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ31250.1 - 9.9e-06 26.1 0.0 0.15 12.6 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ31250.1 - 0.0021 18.3 2.1 0.19 12.1 0.2 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ31250.1 - 0.0029 18.0 2.9 0.11 13.1 0.2 3.9 4 1 0 4 4 3 1 Ankyrin repeat KilA-N PF04383.13 EEQ31250.1 - 0.0094 15.8 0.3 0.0094 15.8 0.3 2.8 2 1 0 2 2 2 1 KilA-N domain DUF4407 PF14362.6 EEQ31250.1 - 0.033 13.5 9.3 0.47 9.8 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Sec8_exocyst PF04048.14 EEQ31250.1 - 0.16 11.8 5.7 0.21 11.5 4.6 1.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Baculo_PEP_C PF04513.12 EEQ31250.1 - 0.22 11.6 2.9 0.43 10.6 1.4 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GPO PF05929.11 EEQ31250.1 - 0.76 9.3 8.3 1.6 8.3 8.3 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1635 PF07795.11 EEQ31250.1 - 0.79 9.5 8.0 0.038 13.9 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Golgin_A5 PF09787.9 EEQ31250.1 - 2.6 7.4 12.8 0.59 9.6 9.0 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 EEQ31250.1 - 3.2 7.9 8.4 8.4 6.6 8.4 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 EEQ31250.1 - 6.2 6.3 10.9 0.43 10.1 4.4 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit YlqD PF11068.8 EEQ31250.1 - 9.4 6.6 10.7 25 5.3 10.7 1.6 1 0 0 1 1 1 0 YlqD protein Complex1_LYR PF05347.15 EEQ31251.1 - 4.8e-06 26.5 0.5 1.1e-05 25.3 0.5 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEQ31251.1 - 0.021 15.6 1.3 0.056 14.2 1.3 1.7 1 0 0 1 1 1 0 Complex1_LYR-like Methyltransf_10 PF05971.12 EEQ31252.1 - 4.1e-40 138.0 0.8 1.6e-28 99.9 0.0 3.2 1 1 2 3 3 3 3 RNA methyltransferase Isochorismatase PF00857.20 EEQ31253.1 - 1.6e-20 74.0 0.1 1.9e-20 73.8 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Pribosyltran_N PF13793.6 EEQ31254.1 - 4.9e-37 126.4 0.0 3.9e-35 120.3 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EEQ31254.1 - 4.5e-35 121.4 0.4 2.3e-30 106.0 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EEQ31254.1 - 1.1e-10 41.2 0.0 3.5e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain CbiJ PF02571.14 EEQ31254.1 - 0.073 12.5 0.1 0.25 10.8 0.0 2.0 2 1 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK NAD_binding_7 PF13241.6 EEQ31255.1 - 8.3e-32 109.7 0.3 1.8e-31 108.7 0.3 1.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EEQ31255.1 - 2.4e-30 104.0 0.0 4.1e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EEQ31255.1 - 5.3e-15 54.5 0.1 1.1e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 EEQ31255.1 - 0.0043 16.3 0.1 0.0062 15.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EEQ31255.1 - 0.034 14.2 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LSDAT_prok PF18171.1 EEQ31255.1 - 0.038 13.2 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote ThiF PF00899.21 EEQ31255.1 - 0.084 12.2 1.9 0.1 12.0 0.2 2.0 1 1 1 2 2 2 0 ThiF family Sec7 PF01369.20 EEQ31256.1 - 5.1e-69 231.6 0.1 1.4e-68 230.1 0.1 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EEQ31256.1 - 4.7e-41 140.3 5.9 4.7e-41 140.3 5.9 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EEQ31256.1 - 2.6e-34 116.9 10.2 1.9e-32 110.9 0.1 6.4 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 EEQ31256.1 - 7.7e-19 68.0 3.5 7.2e-18 64.9 0.5 3.5 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 2-oxoacid_dh PF00198.23 EEQ31257.1 - 2.1e-74 249.9 0.0 2.7e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EEQ31257.1 - 3.6e-17 61.9 0.4 3.6e-17 61.9 0.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EEQ31257.1 - 2.9e-14 53.1 2.0 6.2e-14 52.1 0.9 2.2 2 0 0 2 2 2 1 e3 binding domain SopE_GEF PF07487.13 EEQ31257.1 - 0.04 14.0 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 SopE GEF domain DUF5353 PF17304.2 EEQ31258.1 - 6.1e-35 118.8 1.7 9.5e-35 118.2 1.7 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Rotamase PF00639.21 EEQ31258.1 - 0.00049 21.0 0.7 0.00079 20.3 0.7 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain GOLGA2L5 PF15070.6 EEQ31258.1 - 0.0087 14.8 1.6 0.0095 14.6 1.6 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 SR-25 PF10500.9 EEQ31258.1 - 0.013 15.2 7.3 0.016 14.8 7.3 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OmpH PF03938.14 EEQ31258.1 - 0.016 15.6 4.3 0.027 14.8 4.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ax_dynein_light PF10211.9 EEQ31258.1 - 0.057 13.4 4.4 0.081 12.9 4.4 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain YtxH PF12732.7 EEQ31258.1 - 0.18 12.4 5.8 0.46 11.1 5.8 1.7 1 0 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 EEQ31258.1 - 0.3 11.7 3.2 0.63 10.7 3.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4337 PF14235.6 EEQ31258.1 - 1.7 8.7 5.9 3.1 7.9 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pkinase PF00069.25 EEQ31259.1 - 6.8e-21 74.8 0.0 9.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31259.1 - 1e-18 67.6 0.0 2.1e-18 66.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ31259.1 - 0.061 12.6 0.0 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 EEQ31259.1 - 0.18 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ31261.1 - 1e-16 61.6 0.0 1.3e-16 61.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ31261.1 - 6.1e-05 22.7 0.0 9.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase 6PF2K PF01591.18 EEQ31263.1 - 2.2e-79 265.8 0.3 4.2e-79 265.0 0.0 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EEQ31263.1 - 1.3e-39 135.9 0.0 2.2e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Vps39_1 PF10366.9 EEQ31263.1 - 8.1e-29 100.1 0.0 3.7e-28 98.0 0.0 2.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 EEQ31263.1 - 2.8e-16 59.9 0.0 7.5e-16 58.5 0.0 1.6 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 EEQ31263.1 - 1e-10 42.0 0.0 6e-10 39.5 0.0 2.4 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 2 AAA_33 PF13671.6 EEQ31263.1 - 1.4e-05 25.3 0.0 3.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.28 EEQ31263.1 - 0.028 14.3 0.7 45 4.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Gon7 PF08738.10 EEQ31264.1 - 2.3e-12 46.9 0.7 4.6e-12 46.0 0.7 1.4 1 1 0 1 1 1 1 Gon7 family Ank_2 PF12796.7 EEQ31265.1 - 7.4e-71 234.8 3.7 8.8e-15 55.1 0.6 6.5 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ31265.1 - 3.1e-63 209.4 5.2 8.5e-13 48.5 0.1 9.7 6 1 5 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ31265.1 - 7.4e-52 167.3 7.6 0.00034 20.8 0.0 13.7 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 EEQ31265.1 - 2.4e-50 167.9 8.1 4.4e-08 33.2 0.1 12.0 1 1 12 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 EEQ31265.1 - 5.2e-50 165.8 9.5 0.00046 20.5 0.0 13.4 13 0 0 13 13 13 12 Ankyrin repeat HbrB PF08539.11 EEQ31266.1 - 5.3e-49 166.5 0.0 5.3e-49 166.5 0.0 2.5 3 0 0 3 3 3 1 HbrB-like Peptidase_S64 PF08192.11 EEQ31269.1 - 2.1e-07 29.9 0.1 0.00011 20.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S7 PF00949.21 EEQ31269.1 - 0.0054 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S32 PF05579.13 EEQ31269.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 EEQ31269.1 - 0.43 9.2 0.7 0.65 8.6 0.7 1.1 1 0 0 1 1 1 0 Peptidase S46 Raptor_N PF14538.6 EEQ31270.1 - 0.059 13.3 0.1 0.4 10.6 0.1 2.1 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain V-SNARE_C PF12352.8 EEQ31271.1 - 1.3e-15 57.4 1.0 2.6e-15 56.4 1.0 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EEQ31271.1 - 1e-05 25.4 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Sec20 BAR_2 PF10455.9 EEQ31271.1 - 0.0063 15.7 0.1 0.0088 15.2 0.1 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Sigma70_r4 PF04545.16 EEQ31271.1 - 0.026 14.0 0.1 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 E2F_TDP PF02319.20 EEQ31271.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Antimicrobial10 PF08105.11 EEQ31271.1 - 0.11 12.6 0.3 0.25 11.4 0.3 1.5 1 0 0 1 1 1 0 Metchnikowin family Pox_EPC_I2-L1 PF12575.8 EEQ31271.1 - 0.17 12.1 0.1 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 CoA_binding_3 PF13727.6 EEQ31272.1 - 0.055 13.5 0.7 0.055 13.5 0.7 2.9 4 0 0 4 4 4 0 CoA-binding domain Ldh_1_C PF02866.18 EEQ31273.1 - 3.8e-48 163.6 0.0 7.9e-48 162.5 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EEQ31273.1 - 7.9e-44 149.2 0.0 1.2e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EEQ31273.1 - 0.00016 20.8 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EEQ31273.1 - 0.06 12.9 0.1 0.57 9.7 0.2 2.2 1 1 0 2 2 2 0 Family 4 glycosyl hydrolase AAA PF00004.29 EEQ31274.1 - 1.3e-16 61.2 0.7 4.9e-16 59.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEQ31274.1 - 0.00025 21.0 0.0 0.00073 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ31274.1 - 0.0012 19.1 0.6 0.013 15.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ31274.1 - 0.0057 17.1 2.8 0.0062 16.9 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EEQ31274.1 - 0.026 14.8 0.0 0.088 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EEQ31274.1 - 0.039 13.7 0.0 0.039 13.7 0.0 3.5 2 1 0 2 2 2 0 AAA domain CDC27 PF09507.10 EEQ31274.1 - 0.071 12.5 61.8 0.12 11.7 61.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_33 PF13671.6 EEQ31274.1 - 0.086 13.0 0.1 0.086 13.0 0.1 2.9 2 2 0 2 2 2 0 AAA domain Cwf_Cwc_15 PF04889.12 EEQ31274.1 - 9.5 5.9 76.3 0.062 13.0 51.6 2.4 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Myb_DNA-bind_3 PF12776.7 EEQ31275.1 - 0.0011 19.9 0.1 2.1 9.4 0.0 2.3 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EEQ31275.1 - 0.026 14.6 1.5 1.9 8.6 0.5 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 EEQ31276.1 - 3.6e-15 56.1 0.0 2e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31276.1 - 1e-12 47.9 0.0 6.3e-12 45.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ31276.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Kinase-like MFS_1 PF07690.16 EEQ31277.1 - 1.7e-13 50.2 12.0 1.7e-13 50.2 12.0 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily LSM PF01423.22 EEQ31280.1 - 4.8e-18 64.6 0.0 6.1e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEQ31280.1 - 0.016 15.3 0.0 0.02 15.0 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain DSPc PF00782.20 EEQ31281.1 - 5.3e-10 39.2 0.1 8.9e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEQ31281.1 - 1.4e-05 24.8 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EEQ31281.1 - 0.029 14.4 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 EEQ31281.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EEQ31281.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate AChE_tetra PF08674.10 EEQ31281.1 - 0.12 12.1 0.2 0.4 10.4 0.2 1.9 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain PPR_2 PF13041.6 EEQ31282.1 - 5.9e-12 45.6 0.1 0.039 14.2 0.1 6.3 4 2 1 5 5 5 4 PPR repeat family PPR PF01535.20 EEQ31282.1 - 1.1e-10 41.0 1.2 0.32 11.3 0.0 7.2 7 0 0 7 7 7 1 PPR repeat PPR_3 PF13812.6 EEQ31282.1 - 5.9e-09 35.9 0.0 0.4 10.8 0.0 6.7 6 1 1 7 7 7 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EEQ31282.1 - 1.2e-08 34.6 0.0 0.046 13.1 0.0 3.4 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP SelB-wing_2 PF09106.11 EEQ31282.1 - 0.08 13.2 0.1 4.8 7.5 0.0 2.8 2 0 0 2 2 2 0 Elongation factor SelB, winged helix NB-ARC PF00931.22 EEQ31282.1 - 0.1 11.8 0.3 1 8.5 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain Mic1 PF07035.12 EEQ31282.1 - 0.15 11.7 0.1 3.2 7.4 0.0 2.7 2 1 1 3 3 3 0 Colon cancer-associated protein Mic1-like F-box-like PF12937.7 EEQ31283.1 - 3.7e-05 23.5 1.4 0.00011 22.0 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EEQ31283.1 - 0.086 12.7 0.1 0.31 11.0 0.1 1.9 1 0 0 1 1 1 0 F-box domain LysM PF01476.20 EEQ31284.1 - 1.8e-21 75.9 0.9 1.2e-05 25.3 0.2 5.4 5 1 0 5 5 5 4 LysM domain UPF0203 PF05254.12 EEQ31284.1 - 0.035 14.4 15.4 0.48 10.7 0.6 4.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0203) Aspzincin_M35 PF14521.6 EEQ31285.1 - 5.2e-09 36.8 0.2 1.7e-08 35.1 0.2 2.1 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EEQ31285.1 - 0.0023 16.9 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Glyco_hydro_18 PF00704.28 EEQ31286.1 - 5.3e-67 226.8 2.2 8.6e-67 226.1 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EEQ31286.1 - 6.4e-12 45.7 14.0 6.4e-12 45.7 14.0 6.0 4 1 1 5 5 5 1 Chitin recognition protein DUF4212 PF13937.6 EEQ31286.1 - 0.22 11.9 0.3 0.45 10.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) PLA2_B PF01735.18 EEQ31287.1 - 2.5e-27 95.5 0.0 4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.15 EEQ31288.1 - 2.2e-88 296.9 0.0 3.5e-88 296.2 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Laminin_II PF06009.12 EEQ31288.1 - 0.024 14.7 2.6 2.5 8.1 0.3 2.6 2 0 0 2 2 2 0 Laminin Domain II DASH_Duo1 PF08651.10 EEQ31288.1 - 0.15 11.8 1.9 1.9 8.3 0.0 3.5 3 1 1 4 4 4 0 DASH complex subunit Duo1 P53_TAD PF08563.11 EEQ31288.1 - 0.65 9.6 2.9 1.3 8.5 2.9 1.5 1 0 0 1 1 1 0 P53 transactivation motif BCDHK_Adom3 PF10436.9 EEQ31290.1 - 8.7e-69 230.5 0.0 1.3e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EEQ31290.1 - 5e-13 49.5 0.0 2.4e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EEQ31290.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SKN1 PF03935.15 EEQ31293.1 - 3.6e-193 642.6 0.2 2.1e-168 560.9 1.4 2.0 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) NuiA PF07924.11 EEQ31294.1 - 0.0031 17.9 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 2 2 Nuclease A inhibitor-like protein Ribosomal_L3 PF00297.22 EEQ31295.1 - 5.8e-174 578.3 11.9 7.3e-174 578.0 11.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PGAP1 PF07819.13 EEQ31296.1 - 1.5e-07 31.4 0.0 4.7e-06 26.5 0.0 2.4 1 1 2 3 3 3 1 PGAP1-like protein DUF676 PF05057.14 EEQ31296.1 - 2e-05 24.2 0.3 7.2e-05 22.4 0.1 1.8 1 1 1 2 2 2 1 Putative serine esterase (DUF676) LCAT PF02450.15 EEQ31296.1 - 0.0067 15.6 0.0 0.0092 15.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 EEQ31296.1 - 0.045 13.4 0.0 0.64 9.6 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ31296.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ31296.1 - 0.29 11.7 1.5 2.5 8.6 1.5 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family TPR_1 PF00515.28 EEQ31297.1 - 2.2e-41 138.0 32.8 5.9e-08 32.2 0.1 11.2 10 2 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ31297.1 - 2.3e-38 127.2 22.9 6.8e-06 25.8 0.0 10.7 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ31297.1 - 8.6e-34 112.9 14.9 5.2e-07 29.4 0.0 10.0 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ31297.1 - 5.4e-24 82.8 14.2 0.0001 22.4 0.2 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ31297.1 - 1.8e-20 73.3 19.2 0.00018 22.0 0.1 6.9 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ31297.1 - 2.6e-19 68.6 28.7 4.5e-05 23.0 1.5 9.5 6 2 3 9 9 9 5 TPR repeat TPR_14 PF13428.6 EEQ31297.1 - 6e-18 64.0 27.7 5.2e-05 23.7 0.1 9.2 6 3 4 10 10 9 6 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ31297.1 - 2.6e-16 59.1 25.8 0.0029 18.1 0.0 9.8 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ31297.1 - 2.8e-16 59.5 21.5 0.00015 21.9 0.9 7.6 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ31297.1 - 9.9e-16 58.0 31.5 0.00062 20.2 0.1 6.8 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ31297.1 - 1e-13 50.3 19.6 0.031 14.3 0.1 8.5 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ31297.1 - 7.9e-13 48.4 13.4 0.0054 16.9 0.2 6.6 3 2 4 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ31297.1 - 1.6e-08 34.6 10.2 5.7e-08 32.9 2.1 3.7 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EEQ31297.1 - 0.00012 21.4 21.4 0.014 14.6 0.1 5.5 2 1 4 6 6 5 2 Tetratricopeptide repeat DUF2225 PF09986.9 EEQ31297.1 - 0.0038 17.0 3.8 2 8.1 2.1 3.0 2 2 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 EEQ31297.1 - 0.61 10.0 16.7 16 5.5 0.2 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat NUC173 PF08161.12 EEQ31299.1 - 2.6e-78 262.4 1.1 1.1e-75 253.7 0.1 3.4 3 0 0 3 3 3 2 NUC173 domain Urb2 PF10441.9 EEQ31299.1 - 0.029 14.3 3.1 0.11 12.4 0.1 3.3 3 2 0 3 3 3 0 Urb2/Npa2 family HEAT_2 PF13646.6 EEQ31299.1 - 0.063 13.7 0.6 2.8 8.4 0.5 3.6 2 1 0 2 2 2 0 HEAT repeats RsbRD_N PF14361.6 EEQ31299.1 - 0.078 13.7 1.4 1.2 9.8 0.0 3.8 4 0 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain Vps35 PF03635.17 EEQ31299.1 - 0.12 10.9 0.7 0.58 8.6 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 35 LSM PF01423.22 EEQ31300.1 - 0.0006 19.5 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain TFIIA PF03153.13 EEQ31300.1 - 0.0096 16.0 3.9 0.011 15.7 3.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF334 PF03904.13 EEQ31300.1 - 0.078 12.5 0.3 0.23 11.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF334) Zn_clus PF00172.18 EEQ31301.1 - 5.2e-08 32.9 10.8 8.4e-08 32.2 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EEQ31301.1 - 9.7e-06 24.6 0.0 1.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 EEQ31302.1 - 8.2e-72 241.1 5.6 1.1e-71 240.7 5.6 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3098 PF11297.8 EEQ31302.1 - 0.12 12.0 2.6 2.8 7.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) 6PGD PF00393.19 EEQ31303.1 - 1.9e-76 257.2 0.0 2.6e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EEQ31303.1 - 4.5e-33 114.7 0.1 8.3e-33 113.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EEQ31303.1 - 4.4e-07 29.9 0.1 8.1e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EEQ31303.1 - 3.2e-05 23.9 0.1 6e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 EEQ31303.1 - 0.00061 19.4 0.9 0.0052 16.4 0.3 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 EEQ31303.1 - 0.0013 18.8 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EEQ31303.1 - 0.0031 18.1 0.1 0.0096 16.5 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EEQ31303.1 - 0.0087 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EEQ31303.1 - 0.022 14.1 1.1 0.027 13.8 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EEQ31303.1 - 0.048 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-C2H2_jaz PF12171.8 EEQ31304.1 - 0.0034 17.6 1.7 0.014 15.7 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 EEQ31304.1 - 0.014 15.3 0.3 3.5 7.6 0.0 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 EEQ31304.1 - 0.02 15.3 7.6 0.023 15.1 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-FCS PF06467.14 EEQ31304.1 - 0.065 13.2 0.7 0.16 12.0 0.3 1.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.26 EEQ31304.1 - 0.25 11.9 5.8 0.37 11.3 0.2 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type ADPRTs_Tse2 PF18648.1 EEQ31305.1 - 7.8e-05 22.8 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 Tse2 ADP-ribosyltransferase toxins ADPRTs_Tse2 PF18648.1 EEQ31307.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins FAD_binding_4 PF01565.23 EEQ31308.1 - 6.5e-22 77.8 4.1 1.3e-21 76.8 4.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EEQ31308.1 - 1.6e-08 34.5 0.0 3.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ribonuclease_3 PF00636.26 EEQ31309.1 - 2.9e-37 127.5 0.0 5.3e-17 62.4 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 EEQ31309.1 - 4.3e-23 81.3 0.1 1.1e-22 79.9 0.1 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 EEQ31309.1 - 1.2e-19 70.7 0.1 8.2e-10 38.9 0.0 3.9 4 0 0 4 4 4 3 Ribonuclease-III-like DEAD PF00270.29 EEQ31309.1 - 7e-18 65.0 0.0 1.4e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ31309.1 - 6.5e-16 58.7 0.0 1.7e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ31309.1 - 8.1e-14 52.0 0.0 1.8e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 EEQ31309.1 - 0.0014 19.3 0.0 0.026 15.2 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif YkyA PF10368.9 EEQ31309.1 - 0.55 9.9 7.2 0.21 11.3 2.9 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Proteasome PF00227.26 EEQ31310.1 - 1.1e-56 191.4 0.0 1.1e-31 109.8 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EEQ31310.1 - 9.3e-11 41.2 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.7 EEQ31311.1 - 1.6e-09 37.7 2.2 1.5e-08 34.6 0.6 2.4 2 0 0 2 2 2 1 RING-variant domain GDNF PF02351.16 EEQ31311.1 - 0.063 14.2 0.3 0.1 13.6 0.3 1.3 1 0 0 1 1 1 0 GDNF/GAS1 domain PHD_4 PF16866.5 EEQ31311.1 - 0.09 12.9 1.4 0.8 9.8 0.6 2.3 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 EEQ31311.1 - 0.3 11.5 3.4 5.4 7.4 0.8 2.3 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 EEQ31311.1 - 1.8 8.6 6.2 0.49 10.3 2.8 1.8 2 0 0 2 2 2 0 PHD-finger Fungal_trans PF04082.18 EEQ31314.1 - 0.00043 19.4 1.9 0.00043 19.4 1.9 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ31314.1 - 0.001 19.1 12.7 0.0023 18.0 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EEQ31316.1 - 1.9e-88 297.3 27.3 2.4e-88 297.0 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ31316.1 - 8.8e-12 44.6 48.3 2.9e-08 33.1 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.19 EEQ31316.1 - 8 6.3 13.2 0.93 9.3 0.0 3.6 3 2 0 3 3 3 0 VIT family WD40 PF00400.32 EEQ31319.1 - 5.6e-35 118.8 25.0 1.1e-06 29.3 0.1 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ31319.1 - 1.4e-10 41.3 1.0 0.13 12.6 0.0 6.3 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EEQ31319.1 - 1.7e-10 40.7 0.6 3.2e-10 39.7 0.6 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EEQ31319.1 - 4.6e-07 28.9 4.7 0.065 11.9 0.1 5.3 2 2 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EEQ31319.1 - 3.2e-06 26.7 0.0 0.0023 17.3 0.0 3.3 1 1 2 4 4 4 1 WD40-like domain F-box PF00646.33 EEQ31319.1 - 0.00056 19.7 0.6 0.0015 18.3 0.6 1.9 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 EEQ31319.1 - 0.0042 16.7 1.4 0.013 15.0 0.5 2.1 1 1 1 2 2 2 1 PQQ-like domain F-box_5 PF18511.1 EEQ31319.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 F-box Zip PF02535.22 EEQ31320.1 - 1.3e-39 136.4 12.5 1e-28 100.5 3.1 3.1 2 1 1 3 3 3 3 ZIP Zinc transporter Transp_cyt_pur PF02133.15 EEQ31321.1 - 4.2e-93 312.5 36.5 4.8e-91 305.7 36.5 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 EEQ31322.1 - 1.8e-123 411.8 0.6 4.3e-122 407.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 EEQ31322.1 - 3.2e-26 92.1 5.9 1.2e-17 64.2 0.8 4.6 3 1 1 4 4 4 3 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 EEQ31322.1 - 2.3e-25 89.5 11.2 2.4e-23 82.8 2.5 3.7 3 1 1 4 4 4 2 Hydantoinase/oxoprolinase MutL PF13941.6 EEQ31322.1 - 0.00034 19.3 3.5 0.079 11.5 0.3 2.6 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.20 EEQ31322.1 - 0.00047 19.7 0.4 0.00047 19.7 0.4 2.6 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family CM_1 PF07736.11 EEQ31322.1 - 0.055 13.9 0.0 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 Chorismate mutase type I StbA PF06406.11 EEQ31322.1 - 0.19 10.9 2.9 11 5.1 1.8 2.7 2 1 0 2 2 2 0 StbA protein Hat1_N PF10394.9 EEQ31323.1 - 5.3e-55 186.0 0.1 5.3e-55 186.0 0.1 1.8 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus ENT PF03735.14 EEQ31323.1 - 0.093 12.8 0.9 1.3 9.2 0.2 2.9 3 0 0 3 3 3 0 ENT domain CDC45 PF02724.14 EEQ31323.1 - 5.6 5.1 10.0 7.5 4.7 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein CtIP_N PF10482.9 EEQ31324.1 - 0.12 12.5 1.4 0.2 11.7 1.4 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain adh_short PF00106.25 EEQ31326.1 - 1.3e-27 96.5 0.0 1e-25 90.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ31326.1 - 5.3e-16 58.9 0.0 4.7e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ31326.1 - 2.2e-06 27.7 0.0 3.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EEQ31326.1 - 0.035 14.2 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 EEQ31326.1 - 0.043 13.2 0.0 0.6 9.4 0.0 2.2 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EEQ31326.1 - 0.052 13.0 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Csm1_B PF18211.1 EEQ31326.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Csm1 subunit domain B Polysacc_synt_2 PF02719.15 EEQ31326.1 - 0.18 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.22 EEQ31328.1 - 1.2e-54 185.8 0.0 1.6e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EEQ31329.1 - 3.4e-74 250.3 0.0 4.3e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ca_chan_IQ PF08763.11 EEQ31329.1 - 0.0054 16.9 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain Trypsin_2 PF13365.6 EEQ31332.1 - 3.7e-05 24.7 0.6 0.00011 23.2 0.6 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 EEQ31332.1 - 0.00013 20.6 0.0 0.0089 14.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S32 PF05579.13 EEQ31332.1 - 0.093 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF155 PF02582.14 EEQ31334.1 - 4.8e-51 173.3 0.1 6.9e-51 172.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 U3_snoRNA_assoc PF08297.11 EEQ31335.1 - 1.7e-13 51.1 0.0 1.7e-13 51.1 0.0 4.8 3 1 0 3 3 3 2 U3 snoRNA associated Borrelia_P83 PF05262.11 EEQ31335.1 - 0.34 9.3 18.0 0.54 8.7 18.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Nop53 PF07767.11 EEQ31335.1 - 0.59 9.5 35.8 0.031 13.7 26.9 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CTK3 PF12243.8 EEQ31336.1 - 3.4e-49 165.9 0.1 4.9e-49 165.4 0.1 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EEQ31336.1 - 8.9e-21 73.8 13.3 9.2e-21 73.8 11.8 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus DUF4240 PF14024.6 EEQ31336.1 - 0.047 13.9 0.3 1.1 9.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) P5CR_dimer PF14748.6 EEQ31337.1 - 2.4e-31 108.0 3.0 3.9e-31 107.3 3.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EEQ31337.1 - 3.5e-10 40.3 0.0 1.7e-07 31.7 0.0 2.9 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Voltage_CLC PF00654.20 EEQ31338.1 - 5.7e-88 295.5 23.5 5.7e-88 295.5 23.5 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EEQ31338.1 - 0.00025 21.4 0.0 0.43 11.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain AAA_5 PF07728.14 EEQ31339.1 - 1e-134 443.4 0.0 2.7e-23 82.5 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EEQ31339.1 - 5.5e-47 158.4 2.6 1e-16 61.0 0.0 6.1 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_7 PF12775.7 EEQ31339.1 - 5.4e-31 107.5 0.2 1.6e-05 24.5 0.0 7.2 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA PF00004.29 EEQ31339.1 - 9.2e-31 107.0 0.0 0.00014 22.3 0.0 6.8 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 EEQ31339.1 - 1.1e-30 106.1 0.0 2.3e-11 43.7 0.0 7.4 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ31339.1 - 1.7e-28 100.2 11.1 6e-05 23.5 0.1 8.2 6 2 0 6 6 6 6 AAA ATPase domain Dynein_heavy PF03028.15 EEQ31339.1 - 3.4e-20 72.3 0.0 7.4e-05 22.8 0.0 7.7 7 1 0 7 7 7 4 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 EEQ31339.1 - 2.4e-19 69.5 0.0 0.0026 16.8 0.0 8.3 8 1 0 8 8 7 3 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 EEQ31339.1 - 1.1e-18 67.9 0.7 0.056 13.7 0.0 8.4 8 0 0 8 8 7 4 AAA domain Sigma54_activat PF00158.26 EEQ31339.1 - 1.4e-18 67.2 0.0 0.015 15.0 0.0 6.5 6 0 0 6 6 6 5 Sigma-54 interaction domain TsaE PF02367.17 EEQ31339.1 - 1.6e-16 60.4 3.2 0.088 12.8 0.0 6.9 7 0 0 7 7 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EEQ31339.1 - 1.7e-16 60.9 0.4 0.26 11.8 0.0 7.1 6 0 0 6 6 6 4 AAA domain AAA_33 PF13671.6 EEQ31339.1 - 2.5e-16 60.1 0.0 0.028 14.6 0.0 6.9 6 0 0 6 6 6 3 AAA domain AAA_30 PF13604.6 EEQ31339.1 - 1.8e-14 53.9 0.1 0.07 12.8 0.0 7.5 7 1 0 7 7 6 2 AAA domain AAA_lid_5 PF17865.1 EEQ31339.1 - 6.4e-14 51.9 0.1 3.6e-13 49.5 0.0 2.4 2 0 0 2 2 1 1 Midasin AAA lid domain Mg_chelatase PF01078.21 EEQ31339.1 - 8.9e-14 51.4 3.5 0.72 9.2 0.0 9.3 9 1 0 9 9 9 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EEQ31339.1 - 1.5e-13 50.9 0.0 0.0019 18.2 0.0 7.1 7 0 0 7 7 6 2 AAA domain ABC_tran PF00005.27 EEQ31339.1 - 6.5e-13 49.4 7.2 0.05 14.1 0.0 7.3 7 0 0 7 7 6 3 ABC transporter RuvB_N PF05496.12 EEQ31339.1 - 1.3e-12 47.7 2.1 0.1 12.4 0.0 6.5 7 0 0 7 7 6 4 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EEQ31339.1 - 1.9e-11 44.3 0.7 2.8 8.4 0.0 6.7 6 0 0 6 6 6 1 RNA helicase NACHT PF05729.12 EEQ31339.1 - 6.6e-11 42.4 7.6 0.27 11.1 0.0 7.1 7 0 0 7 7 6 2 NACHT domain AAA_19 PF13245.6 EEQ31339.1 - 1.2e-10 41.8 2.1 2.1 8.7 0.1 6.8 6 0 0 6 6 6 2 AAA domain DUF815 PF05673.13 EEQ31339.1 - 1.3e-10 40.8 2.4 0.22 10.6 0.0 6.3 6 0 0 6 6 6 2 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 EEQ31339.1 - 4.1e-10 39.9 0.5 0.092 12.9 0.0 6.2 6 0 0 6 6 6 2 Sigma-54 interaction domain Rad17 PF03215.15 EEQ31339.1 - 1.2e-09 38.4 1.3 0.087 12.7 0.0 6.2 6 0 0 6 6 6 1 Rad17 P-loop domain AAA_28 PF13521.6 EEQ31339.1 - 4.8e-09 36.7 2.6 0.44 10.8 0.1 6.5 6 0 0 6 6 6 2 AAA domain AAA_25 PF13481.6 EEQ31339.1 - 7.3e-09 35.5 1.2 1.7 8.2 0.0 6.0 6 0 0 6 6 5 2 AAA domain AAA_29 PF13555.6 EEQ31339.1 - 1.7e-08 34.1 0.2 2.4 8.0 0.0 6.5 6 0 0 6 6 6 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EEQ31339.1 - 1.8e-08 34.3 0.0 0.86 9.3 0.0 6.2 6 0 0 6 6 6 1 IstB-like ATP binding protein SRP54 PF00448.22 EEQ31339.1 - 2.3e-08 33.9 2.8 1.2 8.8 0.0 5.9 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EEQ31339.1 - 3.8e-08 32.8 10.2 0.028 13.7 0.0 7.1 8 0 0 8 8 7 1 Zeta toxin PduV-EutP PF10662.9 EEQ31339.1 - 4.6e-08 32.9 1.0 0.28 10.9 0.0 6.2 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 EEQ31339.1 - 9.5e-08 31.4 1.7 0.083 11.9 0.0 5.0 5 0 0 5 5 5 1 Type II/IV secretion system protein AAA_24 PF13479.6 EEQ31339.1 - 3e-07 30.3 0.0 4.2 7.1 0.0 6.2 6 0 0 6 6 6 0 AAA domain RsgA_GTPase PF03193.16 EEQ31339.1 - 6.2e-07 29.5 9.4 2.5 8.0 0.1 6.1 6 0 0 6 6 5 2 RsgA GTPase TniB PF05621.11 EEQ31339.1 - 7.4e-07 28.8 0.1 8.1 5.8 0.0 5.7 6 0 0 6 6 5 0 Bacterial TniB protein Roc PF08477.13 EEQ31339.1 - 1e-06 29.0 3.3 11 6.3 0.0 6.4 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 EEQ31339.1 - 2.9e-06 26.5 0.0 4.4 6.3 0.0 4.8 5 0 0 5 5 4 0 MCM P-loop domain ATPase_2 PF01637.18 EEQ31339.1 - 3.6e-06 27.1 0.0 17 5.3 0.0 6.1 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 EEQ31339.1 - 6.5e-06 25.6 2.8 3 6.9 0.0 5.2 5 0 0 5 5 5 0 TIP49 P-loop domain ResIII PF04851.15 EEQ31339.1 - 2.5e-05 24.4 0.1 0.92 9.5 0.0 4.8 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 EEQ31339.1 - 2.8e-05 24.1 0.0 5.2 6.8 0.0 4.6 5 0 0 5 5 4 0 Bacterial dnaA protein DnaB_C PF03796.15 EEQ31339.1 - 0.00031 20.1 2.5 0.51 9.6 0.0 4.6 5 0 0 5 5 4 1 DnaB-like helicase C terminal domain NTPase_1 PF03266.15 EEQ31339.1 - 0.0004 20.4 5.4 0.78 9.6 0.0 5.1 6 0 0 6 6 4 1 NTPase AAA_17 PF13207.6 EEQ31339.1 - 0.00072 20.0 1.5 7 7.1 0.0 4.7 4 0 0 4 4 4 0 AAA domain ATPase PF06745.13 EEQ31339.1 - 0.00079 18.8 0.3 21 4.4 0.0 5.0 5 0 0 5 5 4 0 KaiC MMR_HSR1 PF01926.23 EEQ31339.1 - 0.0011 19.1 1.6 26 4.9 0.0 5.9 6 0 0 6 6 6 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 EEQ31339.1 - 0.0036 17.1 0.1 16 5.2 0.0 4.8 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EEQ31339.1 - 0.0065 15.9 1.1 7 6.0 0.0 4.5 5 0 0 5 5 4 0 PhoH-like protein DAP3 PF10236.9 EEQ31339.1 - 0.011 15.0 2.6 2.6 7.1 0.0 4.3 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 GAF_2 PF13185.6 EEQ31339.1 - 0.013 15.8 0.0 0.065 13.5 0.0 2.3 1 0 0 1 1 1 0 GAF domain ATP_bind_1 PF03029.17 EEQ31339.1 - 0.031 14.0 7.2 12 5.6 0.0 5.4 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein CPT PF07931.12 EEQ31339.1 - 0.05 13.4 4.5 1.5 8.6 0.0 4.7 6 1 0 6 6 2 0 Chloramphenicol phosphotransferase-like protein dNK PF01712.19 EEQ31339.1 - 0.073 12.9 3.0 2.8 7.7 0.0 3.7 4 0 0 4 4 3 0 Deoxynucleoside kinase SLATT_6 PF18169.1 EEQ31339.1 - 0.098 12.2 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 CbiA PF01656.23 EEQ31339.1 - 0.14 12.2 0.7 42 4.2 0.0 3.8 4 0 0 4 4 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EEQ31339.1 - 0.24 11.0 7.3 27 4.3 0.0 4.9 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 EEQ31339.1 - 0.53 9.7 4.6 31 3.9 0.2 4.6 5 0 0 5 5 4 0 Chromatin associated protein KTI12 Ras PF00071.22 EEQ31339.1 - 0.68 9.5 2.5 69 3.0 0.0 4.3 5 0 0 5 5 5 0 Ras family MobB PF03205.14 EEQ31339.1 - 0.77 9.7 3.7 84 3.1 0.0 5.0 6 0 0 6 6 5 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-grasp_3 PF02655.14 EEQ31340.1 - 3e-09 37.1 0.0 5.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EEQ31340.1 - 3.9e-06 26.6 0.0 6.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EEQ31340.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DevR PF01905.16 EEQ31340.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 APH PF01636.23 EEQ31341.1 - 3e-15 56.8 0.0 4.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ31341.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EEQ31341.1 - 0.00028 19.9 0.2 0.00052 19.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EEQ31341.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 EEQ31341.1 - 0.057 12.8 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 EEQ31341.1 - 0.086 12.4 0.1 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 RIO1 family PRCC PF10253.9 EEQ31343.1 - 3.7e-31 109.6 7.1 3.7e-31 109.6 7.1 2.9 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting BRF1 PF07741.13 EEQ31344.1 - 0.046 14.1 19.2 0.083 13.2 9.5 3.0 2 1 0 2 2 2 0 Brf1-like TBP-binding domain Cytidylate_kin2 PF13189.6 EEQ31344.1 - 0.062 13.4 1.0 0.062 13.4 1.0 2.1 3 0 0 3 3 3 0 Cytidylate kinase-like family Lectin_leg-like PF03388.13 EEQ31345.1 - 2.3e-61 207.1 0.0 3.2e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EEQ31345.1 - 2.5e-06 27.6 0.1 4.1e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EEQ31345.1 - 9.6e-05 22.0 0.0 0.058 12.9 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain PBP1_TM PF14812.6 EEQ31345.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-Tim10_DDP PF02953.15 EEQ31346.1 - 2e-21 75.4 2.5 2e-21 75.4 2.5 1.5 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DUF3475 PF11961.8 EEQ31346.1 - 0.046 13.8 0.5 0.25 11.4 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3475) Pkinase PF00069.25 EEQ31347.1 - 2.4e-72 243.5 0.0 3.2e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31347.1 - 9.5e-37 126.7 0.0 1.3e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ31347.1 - 2e-07 30.6 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEQ31347.1 - 0.023 13.6 0.1 0.037 13.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EEQ31347.1 - 0.054 12.5 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EEQ31347.1 - 0.089 12.7 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family CRIM PF16978.5 EEQ31348.1 - 2.9e-42 144.1 0.0 4.7e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EEQ31348.1 - 7.2e-27 93.8 0.6 1.3e-26 93.0 0.6 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EEQ31348.1 - 0.0098 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 1 TUG ubiquitin-like domain Mito_carr PF00153.27 EEQ31350.1 - 3.6e-13 49.3 0.1 2.2e-06 27.5 0.1 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Peptidase_M28 PF04389.17 EEQ31351.1 - 8.5e-34 117.0 0.4 1.1e-33 116.6 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EEQ31351.1 - 4.7e-05 23.2 0.7 0.00034 20.4 0.7 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EEQ31351.1 - 0.054 13.0 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Nicastrin CENP-T_C PF15511.6 EEQ31352.1 - 6.1e-09 36.0 0.1 7.4e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EEQ31352.1 - 1.9e-05 25.0 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EEQ31352.1 - 7e-05 22.9 0.1 0.0001 22.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EEQ31352.1 - 0.00017 21.8 0.1 0.00036 20.8 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EEQ31352.1 - 0.00021 21.6 0.1 0.00028 21.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EEQ31352.1 - 0.0038 17.3 0.0 0.0045 17.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EEQ31352.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 EEQ31352.1 - 0.052 14.0 0.1 0.098 13.2 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 EEQ31352.1 - 0.1 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region CBM_21 PF03370.13 EEQ31353.1 - 2.8e-29 101.6 0.0 5.7e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EEQ31353.1 - 1.1e-08 35.5 0.2 3.6e-08 33.9 0.2 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) SH3_9 PF14604.6 EEQ31355.1 - 0.0017 18.2 0.2 0.0017 18.2 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EEQ31355.1 - 0.065 12.9 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 SH3 domain HEAT_2 PF13646.6 EEQ31356.1 - 5.3e-46 154.9 38.8 6e-11 42.6 1.1 8.1 3 2 5 8 8 8 7 HEAT repeats HEAT PF02985.22 EEQ31356.1 - 7.1e-33 109.8 18.7 0.002 18.2 0.1 12.9 14 0 0 14 14 13 9 HEAT repeat HEAT_EZ PF13513.6 EEQ31356.1 - 5.5e-21 74.7 40.2 0.0022 18.5 0.9 10.2 7 2 3 10 10 10 6 HEAT-like repeat NACHT PF05729.12 EEQ31356.1 - 1.8e-13 50.8 0.0 4.1e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Arm PF00514.23 EEQ31356.1 - 1.8e-12 46.8 15.3 1.7 8.8 0.1 8.6 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EEQ31356.1 - 2.4e-06 27.7 8.6 0.22 11.5 0.1 7.1 4 2 5 9 9 9 2 non-SMC mitotic condensation complex subunit 1 NB-ARC PF00931.22 EEQ31356.1 - 0.00011 21.5 0.0 0.00024 20.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain RcsD_ABL PF16359.5 EEQ31356.1 - 0.00034 20.7 3.9 2 8.6 0.0 5.7 3 1 1 6 6 6 1 RcsD-ABL domain DctA-YdbH PF11739.8 EEQ31356.1 - 0.0027 17.5 3.5 8.8 6.0 0.0 5.3 3 1 2 5 5 5 1 Dicarboxylate transport DNA_alkylation PF08713.11 EEQ31356.1 - 0.0085 15.8 6.7 0.33 10.6 0.3 4.3 5 0 0 5 5 4 1 DNA alkylation repair enzyme AAA_18 PF13238.6 EEQ31356.1 - 0.029 14.9 0.0 0.33 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain IFRD PF05004.13 EEQ31356.1 - 0.035 13.2 11.9 3.2 6.8 0.5 5.0 1 1 3 5 5 5 0 Interferon-related developmental regulator (IFRD) AAA_22 PF13401.6 EEQ31356.1 - 0.045 14.0 0.0 0.25 11.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEQ31356.1 - 0.05 14.1 0.4 0.5 10.9 0.0 2.8 3 0 0 3 3 3 0 ABC transporter Adaptin_N PF01602.20 EEQ31356.1 - 0.06 11.9 2.9 2 6.9 0.1 3.7 4 1 1 5 5 5 0 Adaptin N terminal region NTPase_1 PF03266.15 EEQ31356.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 EEQ31356.1 - 0.1 12.9 3.3 0.22 11.9 0.0 3.2 4 1 0 4 4 4 0 AAA ATPase domain Sigma54_activat PF00158.26 EEQ31356.1 - 0.15 11.8 0.0 3.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain PEP-utilisers_N PF05524.13 EEQ31356.1 - 0.21 11.8 0.8 7.1 6.8 0.4 3.4 2 1 0 2 2 1 0 PEP-utilising enzyme, N-terminal DUF393 PF04134.12 EEQ31356.1 - 0.36 12.2 2.8 76 4.7 0.1 4.9 2 1 4 6 6 6 0 Protein of unknown function, DUF393 zf-3CxxC PF13695.6 EEQ31357.1 - 4.3e-21 75.3 0.2 5.5e-21 74.9 0.2 1.1 1 0 0 1 1 1 1 Zinc-binding domain HNH_2 PF13391.6 EEQ31358.1 - 8.8e-15 54.6 0.1 1.6e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease EBP PF05241.12 EEQ31360.1 - 2.3e-61 206.4 5.1 2.8e-61 206.1 5.1 1.1 1 0 0 1 1 1 1 Emopamil binding protein Annexin PF00191.20 EEQ31361.1 - 7.7e-57 189.3 0.4 4.7e-15 55.4 0.1 4.2 4 0 0 4 4 4 4 Annexin DUF5617 PF18493.1 EEQ31361.1 - 0.00039 20.4 3.0 0.23 11.6 0.3 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF5617) L31 PF09784.9 EEQ31364.1 - 7.1e-45 151.6 0.5 7.9e-45 151.5 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Acyltransferase PF01553.21 EEQ31365.1 - 7.1e-05 22.4 0.0 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase DEAD PF00270.29 EEQ31366.1 - 3.5e-40 137.6 0.8 6.7e-40 136.7 0.8 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ31366.1 - 7.6e-31 106.7 0.3 8.5e-30 103.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ31366.1 - 1.2e-07 31.9 0.6 2.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RIG-I_C PF18119.1 EEQ31366.1 - 0.034 14.2 1.3 1.4 9.0 0.6 2.5 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain F-box-like PF12937.7 EEQ31367.1 - 4e-07 29.8 2.2 4.4e-07 29.7 0.5 2.0 2 0 0 2 2 2 1 F-box-like Dabb PF07876.12 EEQ31368.1 - 5.4e-15 55.8 1.3 3.6e-12 46.7 0.3 2.1 1 1 1 2 2 2 2 Stress responsive A/B Barrel Domain NB-ARC PF00931.22 EEQ31369.1 - 5.6e-14 51.9 0.0 1.6e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_12 PF13424.6 EEQ31369.1 - 2.7e-08 34.0 6.0 7.3e-08 32.6 2.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ31369.1 - 3.6e-06 26.6 4.6 0.0076 16.0 0.9 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat AAA_22 PF13401.6 EEQ31369.1 - 0.0011 19.2 0.0 0.003 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_10 PF13374.6 EEQ31369.1 - 0.0073 16.1 2.7 1.6 8.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ31369.1 - 0.017 15.8 4.4 0.11 13.1 1.3 3.5 2 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ31369.1 - 0.027 14.7 0.2 0.079 13.2 0.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EEQ31369.1 - 0.028 14.5 0.5 0.028 14.5 0.5 3.2 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ31369.1 - 0.039 14.2 2.7 10 6.6 0.6 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ31369.1 - 0.053 14.0 2.9 0.28 11.7 0.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ31369.1 - 0.056 12.8 0.4 0.098 12.0 0.4 1.3 1 0 0 1 1 1 0 MalT-like TPR region TPR_14 PF13428.6 EEQ31369.1 - 0.088 13.7 5.2 2.8 9.0 0.1 4.4 2 1 2 4 4 4 0 Tetratricopeptide repeat AAA_18 PF13238.6 EEQ31369.1 - 0.18 12.3 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF302 PF03625.14 EEQ31369.1 - 0.19 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF302 DUF2225 PF09986.9 EEQ31369.1 - 0.22 11.2 0.1 0.45 10.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) PemK_toxin PF02452.17 EEQ31370.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system PetL PF05115.14 EEQ31372.1 - 1.2 9.2 4.4 1.9 8.5 4.4 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) RRN3 PF05327.11 EEQ31373.1 - 0.59 8.6 3.7 0.93 8.0 3.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 tRNA-synt_1d PF00750.19 EEQ31374.1 - 5.6e-97 324.8 6.7 2.3e-95 319.5 6.7 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EEQ31374.1 - 3.5e-28 98.2 0.0 9e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EEQ31374.1 - 1.8e-05 25.2 1.8 4.9e-05 23.8 0.0 2.6 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain DUF16 PF01519.16 EEQ31374.1 - 0.082 13.4 2.9 0.38 11.2 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 WD40 PF00400.32 EEQ31375.1 - 8.1e-08 32.8 26.8 1.6e-05 25.6 0.5 7.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ31375.1 - 0.0003 21.0 0.3 2.6 8.4 0.0 5.1 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ31375.1 - 0.062 12.2 1.9 0.37 9.7 0.3 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EEQ31375.1 - 4.2 7.4 8.0 13 5.9 0.1 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat FAD_binding_6 PF00970.24 EEQ31376.1 - 3.5e-32 110.7 0.0 5.9e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EEQ31376.1 - 7.8e-29 100.5 0.0 1.2e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EEQ31376.1 - 9.1e-06 25.9 0.0 0.0028 17.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF4176 PF13780.6 EEQ31376.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) FAD_binding_9 PF08021.11 EEQ31376.1 - 0.2 11.9 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3605 PF12239.8 EEQ31377.1 - 1.5e-59 200.7 0.1 1.8e-59 200.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) SMC_N PF02463.19 EEQ31378.1 - 6.9e-64 215.3 28.2 1.7e-63 214.0 28.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEQ31378.1 - 6.6e-31 107.0 0.4 9e-30 103.4 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EEQ31378.1 - 5.7e-17 62.5 0.7 1.4e-11 44.8 0.2 3.7 4 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EEQ31378.1 - 3.9e-13 49.8 30.8 1e-08 35.3 17.8 4.3 2 2 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 EEQ31378.1 - 4.6e-12 46.8 29.2 4.6e-12 46.8 29.2 6.6 2 2 1 4 4 4 1 AAA domain AAA_29 PF13555.6 EEQ31378.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6_N PF17675.1 EEQ31378.1 - 0.27 11.8 129.9 0.049 14.2 6.9 8.3 4 2 4 8 8 8 0 Apg6 coiled-coil region ABC_tran PF00005.27 EEQ31378.1 - 0.48 10.9 0.0 0.48 10.9 0.0 6.0 3 2 1 5 5 5 0 ABC transporter DUF3800 PF12686.7 EEQ31378.1 - 1.2 9.8 5.0 50 4.6 0.8 4.3 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) DUF87 PF01935.17 EEQ31378.1 - 2.8 8.0 0.0 2.8 8.0 0.0 6.4 3 2 4 7 7 7 0 Helicase HerA, central domain RIO1 PF01163.22 EEQ31379.1 - 1.1e-71 240.3 0.1 1.1e-71 240.3 0.1 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EEQ31379.1 - 2.4e-06 27.7 0.4 0.00064 19.7 0.2 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEQ31379.1 - 0.0011 18.4 0.6 0.011 15.1 0.6 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEQ31379.1 - 0.039 12.7 0.1 0.088 11.6 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EEQ31379.1 - 0.11 12.0 0.7 0.35 10.4 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase PTH2 PF01981.16 EEQ31380.1 - 0.21 11.9 0.5 0.44 10.8 0.1 1.7 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 WD40 PF00400.32 EEQ31384.1 - 5.3e-47 156.8 20.8 5.8e-09 36.4 0.5 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EEQ31384.1 - 7.1e-15 54.6 0.2 1.5e-14 53.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ31384.1 - 7.8e-12 44.8 0.2 2.5e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 EEQ31384.1 - 5.9e-10 38.4 9.7 0.015 13.9 0.2 5.6 3 3 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EEQ31384.1 - 1.2e-09 38.4 0.2 0.0014 18.9 0.0 5.0 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EEQ31384.1 - 0.00055 19.8 0.0 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 F-box WD40_like PF17005.5 EEQ31384.1 - 0.0021 17.5 0.2 0.0033 16.8 0.2 1.3 1 0 0 1 1 1 1 WD40-like domain PRANC PF09372.10 EEQ31384.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 PRANC domain SR-25 PF10500.9 EEQ31384.1 - 6.6 6.3 12.5 0.25 10.9 6.4 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein APG17 PF04108.12 EEQ31385.1 - 1e-132 443.0 0.2 1.2e-132 442.8 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 RasGAP_C PF03836.15 EEQ31385.1 - 0.0045 17.1 2.4 1.9 8.6 0.1 3.6 4 0 0 4 4 4 1 RasGAP C-terminus Tweety PF04906.13 EEQ31385.1 - 0.055 12.1 0.2 3 6.4 0.0 2.6 2 0 0 2 2 2 0 Tweety LprI PF07007.12 EEQ31385.1 - 0.13 13.0 2.5 9.8 6.9 0.1 3.0 2 1 0 2 2 2 0 Lysozyme inhibitor LprI DUF1542 PF07564.11 EEQ31385.1 - 0.18 11.9 1.4 0.84 9.8 1.4 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DinB_2 PF12867.7 EEQ31385.1 - 1.1 9.7 5.9 0.85 10.1 0.2 3.3 2 1 1 3 3 3 0 DinB superfamily COG2 PF06148.11 EEQ31385.1 - 4 7.5 6.6 3.7 7.6 0.3 3.5 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Oxidored_q4 PF00507.19 EEQ31387.1 - 0.15 12.3 0.2 0.15 12.3 0.2 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 MadM PF03818.13 EEQ31388.1 - 0.32 10.9 2.2 15 5.5 0.3 2.8 2 1 1 3 3 3 0 Malonate/sodium symporter MadM subunit CHAT PF12770.7 EEQ31389.1 - 3.9e-33 115.1 0.0 6.6e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EEQ31389.1 - 2.1e-30 103.7 21.5 7e-06 25.8 0.3 10.7 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ31389.1 - 2.8e-09 37.1 7.0 6.3 7.2 0.0 8.2 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ31389.1 - 7.5e-09 35.1 0.2 8.6 6.9 0.0 8.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ31389.1 - 3e-06 26.9 0.6 6.1 7.2 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ31389.1 - 0.00012 22.6 13.8 10 7.2 0.0 9.7 9 1 2 11 11 9 1 Tetratricopeptide repeat DUF4404 PF14357.6 EEQ31389.1 - 0.00017 22.2 3.0 3.4 8.4 0.4 4.5 5 0 0 5 5 5 2 Domain of unknown function (DUF4404) TPR_16 PF13432.6 EEQ31389.1 - 0.0005 20.7 1.5 0.86 10.3 0.1 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ31389.1 - 0.0005 19.7 5.3 15 5.4 0.1 7.0 8 0 0 8 8 8 0 TPR repeat Peptidase_C25 PF01364.18 EEQ31389.1 - 0.0018 17.5 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C25 CENP-Q PF13094.6 EEQ31389.1 - 0.0022 18.2 1.0 9 6.5 0.0 3.8 4 0 0 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit RPN6_N PF18055.1 EEQ31389.1 - 0.061 13.7 0.5 34 4.8 0.0 4.1 3 1 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_17 PF13431.6 EEQ31389.1 - 0.078 13.4 6.6 0.61 10.6 0.0 5.4 8 0 0 8 8 6 0 Tetratricopeptide repeat ATP-synt_ab PF00006.25 EEQ31389.1 - 0.14 11.8 0.0 31 4.1 0.0 3.8 4 1 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain ATG16 PF08614.11 EEQ31389.1 - 6.5 6.9 8.4 1.2 9.3 0.1 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) TPR_12 PF13424.6 EEQ31390.1 - 1.4e-55 185.5 6.2 5.9e-20 71.3 0.1 4.6 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ31390.1 - 2e-54 180.0 10.0 2.8e-11 42.9 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ31390.1 - 2.7e-20 70.8 4.5 0.00022 21.0 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ31390.1 - 1.2e-16 61.1 7.4 6.2e-07 29.1 0.2 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_1 PF00515.28 EEQ31390.1 - 7.2e-11 41.4 14.6 0.012 15.4 0.0 6.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ31390.1 - 3.3e-09 36.2 15.0 0.55 10.5 0.0 5.9 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ31390.1 - 3.1e-08 33.4 1.0 0.064 13.7 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ31390.1 - 1.2e-07 32.2 0.8 2.1 9.0 0.0 5.3 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ31390.1 - 3.6e-07 29.9 9.8 1.3 9.4 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ31390.1 - 1.2e-06 28.8 3.9 2 9.5 0.0 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EEQ31390.1 - 1.6e-06 28.2 0.0 18 6.3 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ31390.1 - 7e-05 23.3 7.8 0.22 12.1 0.2 4.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 EEQ31390.1 - 8e-05 22.0 0.1 0.024 13.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ31390.1 - 0.00074 19.7 2.4 3.4 8.0 0.1 4.5 2 1 3 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EEQ31390.1 - 0.0044 17.0 9.2 0.82 9.7 0.2 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 EEQ31390.1 - 0.051 13.6 3.2 4.1 7.5 0.0 4.0 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 EEQ31390.1 - 0.1 12.3 1.2 3.6 7.4 0.1 3.9 3 0 0 3 3 3 0 TPR repeat SPO22 PF08631.10 EEQ31390.1 - 0.13 11.7 2.2 0.64 9.4 0.8 2.3 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like BTAD PF03704.17 EEQ31390.1 - 0.15 12.5 1.6 0.63 10.5 0.2 2.5 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 EEQ31390.1 - 0.72 10.6 4.7 26 5.7 0.1 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat kleA_kleC PF17383.2 EEQ31390.1 - 1.9 8.9 6.8 53 4.2 0.0 4.5 4 1 1 5 5 5 0 Uncharacterized KorC regulated protein A NAD_binding_10 PF13460.6 EEQ31391.1 - 2e-11 44.2 0.0 5.5e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ31391.1 - 0.00014 21.5 0.2 0.00051 19.7 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EEQ31391.1 - 0.004 16.6 0.1 0.034 13.6 0.1 1.9 1 1 1 2 2 2 1 short chain dehydrogenase MFS_1 PF07690.16 EEQ31392.1 - 1.9e-49 168.5 36.9 1.9e-49 168.5 36.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ31392.1 - 1e-08 34.5 25.0 4.9e-08 32.3 25.0 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EEQ31392.1 - 1.1e-06 28.2 8.8 2.6e-06 27.0 8.8 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EEQ31392.1 - 4.1e-06 25.5 5.7 7.5e-06 24.6 5.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EEQ31392.1 - 0.58 8.4 14.4 0.095 11.0 9.6 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M28 PF04389.17 EEQ31398.1 - 1.7e-28 99.7 0.1 4.9e-28 98.2 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EEQ31398.1 - 1.9e-08 34.3 0.0 2.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EEQ31398.1 - 0.0038 16.3 0.0 0.011 14.7 0.0 1.7 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Nicastrin PF05450.15 EEQ31398.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Nicastrin PGAP1 PF07819.13 EEQ31399.1 - 8.8e-84 280.8 0.0 1.4e-83 280.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EEQ31399.1 - 6.9e-05 23.6 0.1 0.00013 22.6 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EEQ31399.1 - 0.00052 19.9 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EEQ31399.1 - 0.00071 19.3 0.4 0.0019 17.9 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EEQ31399.1 - 0.0024 17.5 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EEQ31399.1 - 0.005 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 EEQ31399.1 - 0.0059 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 EEQ31399.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ResIII PF04851.15 EEQ31401.1 - 3.9e-26 92.1 0.0 1e-25 90.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ31401.1 - 1.3e-14 54.5 0.0 2.9e-12 46.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ31401.1 - 1.4e-11 44.5 0.0 1.3e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EEQ31401.1 - 5.8e-06 26.1 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 EEQ31401.1 - 9.9e-06 25.0 0.0 1.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SwrA PF17423.2 EEQ31401.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Swarming motility protein UvrD-helicase PF00580.21 EEQ31401.1 - 0.22 11.0 1.9 2.7 7.4 0.0 2.6 3 1 1 4 4 4 0 UvrD/REP helicase N-terminal domain Myb_DNA-binding PF00249.31 EEQ31402.1 - 0.014 15.5 0.0 0.17 12.1 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain SWIRM PF04433.17 EEQ31403.1 - 6.1e-31 106.6 0.0 1.5e-30 105.3 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EEQ31403.1 - 1.5e-30 105.0 9.1 1.5e-30 105.0 9.1 1.9 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EEQ31403.1 - 2.7e-09 37.1 0.1 4.8e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ31403.1 - 4.4e-06 26.8 0.2 9.5e-06 25.8 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EEQ31403.1 - 1.5 8.7 3.6 0.63 9.9 0.1 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type AAA PF00004.29 EEQ31404.1 - 1e-11 45.4 0.0 1.9e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ31404.1 - 2.7e-06 27.7 0.0 6.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EEQ31404.1 - 3.3e-06 27.2 0.1 1.1e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EEQ31404.1 - 1.1e-05 25.4 0.2 5.3e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 EEQ31404.1 - 2.6e-05 24.0 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EEQ31404.1 - 0.00091 19.3 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEQ31404.1 - 0.0029 18.0 0.0 0.012 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EEQ31404.1 - 0.0097 16.1 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EEQ31404.1 - 0.043 13.7 0.1 0.09 12.7 0.1 1.6 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.12 EEQ31404.1 - 0.059 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF1776 PF08643.10 EEQ31404.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) AAA_24 PF13479.6 EEQ31404.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EEQ31404.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EEQ31404.1 - 0.16 12.3 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ31404.1 - 0.16 12.5 0.1 0.38 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain MDMPI_N PF11716.8 EEQ31405.1 - 0.08 13.6 1.0 0.08 13.6 1.0 1.8 1 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain LysM PF01476.20 EEQ31407.1 - 5.5e-14 51.9 0.0 0.0041 17.1 0.0 4.0 4 0 0 4 4 4 3 LysM domain Ycf34 PF10718.9 EEQ31407.1 - 0.099 13.3 0.3 1.2e+02 3.5 0.0 3.4 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 HTH_Tnp_1 PF01527.20 EEQ31407.1 - 0.14 12.5 0.0 31 5.0 0.0 2.3 2 0 0 2 2 2 0 Transposase APH PF01636.23 EEQ31409.1 - 3.5e-13 50.1 0.0 6.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ31409.1 - 0.0012 18.5 0.1 0.0025 17.4 0.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase ETF PF01012.21 EEQ31411.1 - 3.9e-41 140.9 1.4 7e-41 140.1 1.4 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EEQ31411.1 - 2.9e-33 113.7 0.1 6.1e-33 112.7 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L1 PF00687.21 EEQ31412.1 - 6.6e-56 189.3 0.1 6.6e-56 189.3 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family SUN PF03856.13 EEQ31413.1 - 2.9e-62 210.3 4.1 3.9e-62 209.9 4.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) APH PF01636.23 EEQ31415.1 - 2.1e-16 60.6 0.0 1.7e-15 57.6 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF4388 PF14332.6 EEQ31415.1 - 0.075 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) Pkinase PF00069.25 EEQ31416.1 - 1.2e-23 83.8 0.0 1.8e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31416.1 - 3.9e-12 46.0 0.0 7e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ31416.1 - 0.0068 15.2 0.1 0.0098 14.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EEQ31416.1 - 0.0077 15.6 0.1 0.019 14.3 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ31416.1 - 0.015 15.2 0.6 0.091 12.7 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family TetR PF13972.6 EEQ31416.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor SCP2 PF02036.17 EEQ31416.1 - 0.16 12.5 0.1 0.44 11.1 0.0 1.7 2 0 0 2 2 2 0 SCP-2 sterol transfer family Glyco_transf_8 PF01501.20 EEQ31417.1 - 1.5e-12 47.7 0.0 2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF5560 PF17715.1 EEQ31417.1 - 1.7 8.0 3.5 6.1 6.3 2.9 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5560) Glyco_hydro_18 PF00704.28 EEQ31419.1 - 8.6e-78 262.2 0.2 1.1e-77 261.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EEQ31419.1 - 1.6e-11 44.1 0.0 3.6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 LysM domain FMO-like PF00743.19 EEQ31420.1 - 2.3e-12 46.1 0.6 3.5e-09 35.6 0.0 3.0 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EEQ31420.1 - 7e-11 41.9 0.2 0.00013 21.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ31420.1 - 5.1e-08 32.5 0.0 4.7e-05 22.8 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ31420.1 - 1.5e-05 24.4 0.0 0.0015 17.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EEQ31420.1 - 1.7e-05 24.6 0.0 0.00024 20.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ31420.1 - 3.7e-05 23.9 0.1 8.9e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EEQ31420.1 - 0.0028 17.7 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EEQ31420.1 - 0.012 14.9 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EEQ31420.1 - 0.014 15.4 0.1 0.12 12.3 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EEQ31420.1 - 0.16 11.3 0.4 0.24 10.7 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase MIF4G PF02854.19 EEQ31421.1 - 2.4e-45 154.8 0.0 1.1e-21 77.5 0.0 4.1 4 1 1 5 5 5 3 MIF4G domain Upf2 PF04050.14 EEQ31421.1 - 7.6e-40 136.8 12.0 7.6e-40 136.8 12.0 3.2 4 0 0 4 4 4 1 Up-frameshift suppressor 2 TPK_catalytic PF04263.16 EEQ31422.1 - 1.3e-29 102.7 0.0 2.1e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EEQ31422.1 - 7.8e-16 57.6 0.2 1.3e-15 56.8 0.2 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.13 EEQ31423.1 - 9e-07 28.9 5.3 1.5e-06 28.2 5.3 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EEQ31423.1 - 0.0023 18.3 1.3 0.0041 17.5 1.3 1.5 1 0 0 1 1 1 1 GCK domain 23S_rRNA_IVP PF05635.11 EEQ31424.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein Mito_carr PF00153.27 EEQ31425.1 - 6.1e-63 208.8 4.2 2.4e-20 72.2 0.9 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein ER-remodelling PF14755.6 EEQ31425.1 - 0.003 17.9 1.0 0.005 17.1 1.0 1.3 1 0 0 1 1 1 1 Intracellular membrane remodeller YhdX PF17444.2 EEQ31425.1 - 0.18 11.7 2.2 0.25 11.2 0.6 1.9 2 0 0 2 2 2 0 Uncharacterized YhdX-like UPF0121 PF03661.13 EEQ31426.1 - 4e-30 105.0 5.6 5.4e-30 104.6 5.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Sel_put PF04328.13 EEQ31426.1 - 0.19 11.7 0.5 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 Selenoprotein, putative MOFRL PF05161.13 EEQ31427.1 - 0.046 13.9 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 MOFRL family Septin PF00735.18 EEQ31428.1 - 3.1e-115 384.3 0.2 3.1e-115 384.3 0.2 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EEQ31428.1 - 9.7e-08 32.1 1.1 1.8e-07 31.2 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ31428.1 - 0.00052 19.6 2.6 0.01 15.4 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EEQ31428.1 - 0.00058 20.4 4.9 0.027 15.0 0.0 2.7 2 1 1 3 3 3 1 ABC transporter AAA_16 PF13191.6 EEQ31428.1 - 0.0018 18.7 0.2 0.0061 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ31428.1 - 0.0022 17.9 0.7 0.0022 17.9 0.7 3.5 3 1 0 3 3 3 1 RsgA GTPase Roc PF08477.13 EEQ31428.1 - 0.0023 18.1 0.0 0.0055 16.9 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EEQ31428.1 - 0.0047 16.5 0.0 0.02 14.5 0.0 2.1 1 1 0 1 1 1 1 Ras family AIG1 PF04548.16 EEQ31428.1 - 0.005 16.2 0.0 0.005 16.2 0.0 2.3 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.6 EEQ31428.1 - 0.0076 16.5 0.5 0.047 14.0 0.0 2.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EEQ31428.1 - 0.021 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NolB PF17398.2 EEQ31428.1 - 0.027 14.9 0.3 0.051 14.0 0.3 1.4 1 0 0 1 1 1 0 Nodulation protein NolB Dynamin_N PF00350.23 EEQ31428.1 - 0.037 14.1 7.5 0.96 9.5 0.0 3.9 4 1 0 4 4 4 0 Dynamin family FtsK_SpoIIIE PF01580.18 EEQ31428.1 - 0.063 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EEQ31428.1 - 0.071 12.8 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2937 PF11157.8 EEQ31428.1 - 0.078 12.7 5.3 0.23 11.1 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) RNA_helicase PF00910.22 EEQ31428.1 - 0.082 13.3 1.3 1 9.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 EEQ31428.1 - 0.12 12.9 9.6 16 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 EEQ31428.1 - 0.15 11.6 8.0 0.27 10.8 8.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 EEQ31428.1 - 0.45 10.3 4.3 3.7 7.2 0.0 3.0 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 EEQ31428.1 - 0.68 10.0 5.2 6.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Amino_oxidase PF01593.24 EEQ31429.1 - 1.5e-13 50.9 0.0 1.4e-10 41.1 0.0 3.0 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EEQ31429.1 - 4.6e-11 42.8 0.0 2e-10 40.7 0.0 2.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ31429.1 - 0.0086 15.7 0.0 0.055 13.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EEQ31429.1 - 0.021 14.8 0.0 0.27 11.2 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EEQ31429.1 - 0.052 12.8 0.0 0.53 9.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EEQ31429.1 - 0.056 12.3 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase RFC1 PF08519.12 EEQ31430.1 - 2.7e-58 196.6 0.2 2.2e-57 193.7 0.1 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EEQ31430.1 - 2.3e-14 53.5 0.0 8.2e-14 51.7 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EEQ31430.1 - 2e-09 38.0 0.9 3.5e-09 37.2 0.1 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEQ31430.1 - 0.0004 20.3 0.0 0.00095 19.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EEQ31430.1 - 0.00049 20.4 0.0 0.0019 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EEQ31430.1 - 0.003 17.3 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEQ31430.1 - 0.0037 17.7 0.1 0.016 15.6 0.1 1.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EEQ31430.1 - 0.0057 16.8 0.0 0.021 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EEQ31430.1 - 0.0063 16.5 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEQ31430.1 - 0.015 15.9 0.0 0.047 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EEQ31430.1 - 0.042 13.5 0.1 0.084 12.6 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 EEQ31430.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ31430.1 - 0.092 12.7 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 EEQ31430.1 - 0.11 12.5 0.1 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 EEQ31430.1 - 0.12 12.7 0.0 6.3 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA C-terminal domain Ribosomal_L16 PF00252.18 EEQ31431.1 - 1.4e-30 106.0 0.2 1.8e-30 105.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 EEQ31432.1 - 5.9e-11 42.4 0.1 1.1e-10 41.5 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EEQ31432.1 - 6.9e-07 29.7 0.1 1.3e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ31432.1 - 3e-06 27.6 0.0 1.3e-05 25.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ31432.1 - 0.00052 20.4 0.5 0.0047 17.3 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EEQ31432.1 - 0.0011 18.8 0.4 0.0029 17.4 0.4 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EEQ31432.1 - 0.013 16.0 0.1 0.026 15.1 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.15 EEQ31432.1 - 0.045 13.7 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain T4SS-DNA_transf PF02534.14 EEQ31432.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ResIII PF04851.15 EEQ31432.1 - 0.12 12.3 0.4 0.45 10.5 0.4 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CtaG_Cox11 PF04442.14 EEQ31433.1 - 6.7e-62 208.0 0.1 9.2e-62 207.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Polysacc_deac_1 PF01522.21 EEQ31434.1 - 1.2e-29 102.7 0.0 1.9e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.9 EEQ31434.1 - 0.055 11.8 0.1 0.21 9.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2194) PT PF04886.12 EEQ31434.1 - 0.63 9.6 39.3 1.8e+04 -8.7 39.3 2.6 1 1 0 1 1 1 0 PT repeat Pkinase PF00069.25 EEQ31436.1 - 7.2e-09 35.4 0.0 1.4e-08 34.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31436.1 - 0.011 15.0 0.0 0.022 14.1 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase Peptidase_M35 PF02102.15 EEQ31438.1 - 2.4e-107 359.0 6.0 2.8e-107 358.7 6.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EEQ31438.1 - 5e-42 143.9 0.4 5e-42 143.9 0.4 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EEQ31438.1 - 6.8e-05 22.6 0.8 0.00016 21.4 0.8 1.5 1 1 0 1 1 1 1 Putative peptidase family IceA2 PF05862.11 EEQ31438.1 - 0.036 14.0 1.1 0.092 12.7 1.1 1.7 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein Semialdhyde_dhC PF02774.18 EEQ31439.1 - 2.6e-37 128.7 0.0 3.6e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EEQ31439.1 - 1.1e-28 100.1 0.0 4.1e-28 98.3 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EEQ31439.1 - 0.0013 19.6 0.0 0.0024 18.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 EEQ31439.1 - 0.1 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TMEM135_C_rich PF15982.5 EEQ31440.1 - 4.4e-05 24.1 0.5 9.9e-05 22.9 0.5 1.6 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 HLH PF00010.26 EEQ31441.1 - 9.6e-07 28.7 0.3 3e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Ndc1_Nup PF09531.10 EEQ31441.1 - 7.9 5.0 10.1 14 4.3 10.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NST1 PF13945.6 EEQ31441.1 - 8.7 6.4 12.7 0.38 10.8 6.4 1.9 2 0 0 2 2 2 0 Salt tolerance down-regulator BTRD1 PF17660.1 EEQ31443.1 - 3.8e-45 151.5 8.2 4.3e-17 61.7 0.8 3.3 3 0 0 3 3 3 3 Bacterial tandem repeat domain 1 Ser_hydrolase PF06821.13 EEQ31443.1 - 0.056 13.3 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Glyoxalase_4 PF13669.6 EEQ31443.1 - 0.14 12.4 0.0 0.48 10.7 0.0 1.9 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BLIP PF07467.11 EEQ31444.1 - 0.024 15.2 0.0 0.74 10.4 0.0 2.5 3 0 0 3 3 3 0 Beta-lactamase inhibitor (BLIP) CENP-Q PF13094.6 EEQ31445.1 - 2.6e-38 131.9 3.0 4.4e-38 131.1 3.0 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit BRE1 PF08647.11 EEQ31445.1 - 0.16 12.1 12.6 0.062 13.4 9.3 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4337 PF14235.6 EEQ31445.1 - 0.25 11.4 4.0 0.5 10.5 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) LMBR1 PF04791.16 EEQ31445.1 - 0.37 9.6 0.7 0.47 9.3 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RPN2_C PF18004.1 EEQ31445.1 - 0.68 9.8 7.0 0.29 11.1 3.5 2.0 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain ERM PF00769.19 EEQ31445.1 - 4.1 7.1 17.8 0.74 9.6 13.2 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Spc24 PF08286.11 EEQ31445.1 - 5.7 7.2 8.2 10 6.5 7.3 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Zn_clus PF00172.18 EEQ31446.1 - 0.015 15.4 3.8 0.028 14.5 3.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SPO22 PF08631.10 EEQ31447.1 - 5.4e-26 91.7 0.9 8.3e-26 91.1 0.9 1.3 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like DUF4351 PF14261.6 EEQ31448.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) WD40 PF00400.32 EEQ31449.1 - 2.2e-20 72.6 7.3 0.00074 20.3 0.0 8.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ31449.1 - 0.0004 20.6 0.0 9.8 6.6 0.0 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain FTA2 PF13095.6 EEQ31450.1 - 7.9e-40 136.8 0.0 9.4e-38 130.0 0.0 2.1 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Radial_spoke PF04712.12 EEQ31451.1 - 0.017 14.1 3.4 0.026 13.5 3.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4611 PF15387.6 EEQ31451.1 - 0.15 12.3 6.2 0.32 11.2 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 EEQ31451.1 - 0.26 11.7 12.0 0.51 10.8 12.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 EEQ31451.1 - 0.4 8.9 3.9 0.61 8.3 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EEQ31451.1 - 0.55 9.9 2.3 1.1 8.9 2.3 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EEQ31451.1 - 0.66 9.2 8.0 1 8.6 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 EEQ31451.1 - 1.5 9.5 8.1 0.22 12.2 3.7 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein MFS_1 PF07690.16 EEQ31452.1 - 1.2e-36 126.4 20.8 1.2e-36 126.4 20.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ31452.1 - 5.7e-08 32.0 7.5 5.7e-08 32.0 7.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.16 EEQ31452.1 - 0.014 13.7 1.6 0.025 12.8 1.6 1.3 1 0 0 1 1 1 0 BT1 family PNTB_4TM PF12769.7 EEQ31452.1 - 2.5 8.6 6.8 0.88 10.1 3.1 2.2 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Sugar_tr PF00083.24 EEQ31453.1 - 4.3e-81 273.1 26.4 4.9e-81 272.9 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ31453.1 - 1.6e-23 83.2 23.2 1.6e-23 83.2 23.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily GCN5L1 PF06320.13 EEQ31454.1 - 8.1e-17 61.4 4.1 9.4e-17 61.2 4.1 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF2884 PF11101.8 EEQ31454.1 - 0.02 14.4 2.2 0.037 13.6 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF2570 PF10828.8 EEQ31454.1 - 0.024 14.4 1.6 0.032 14.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SAPIS-gp6 PF16722.5 EEQ31454.1 - 0.027 14.9 1.4 0.05 14.0 1.4 1.5 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus DASH_Dad2 PF08654.10 EEQ31454.1 - 0.055 13.9 2.2 0.11 13.0 1.7 1.7 1 1 1 2 2 2 0 DASH complex subunit Dad2 SCP-1 PF05483.12 EEQ31454.1 - 0.064 11.3 5.6 0.076 11.0 5.6 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) DivIC PF04977.15 EEQ31454.1 - 0.064 13.0 4.3 0.12 12.1 4.3 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF3552 PF12072.8 EEQ31454.1 - 0.073 12.5 6.8 0.035 13.5 4.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF630 PF04783.12 EEQ31454.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF630) HAUS6_N PF14661.6 EEQ31454.1 - 0.14 11.7 2.4 0.17 11.5 2.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Nsp1_C PF05064.13 EEQ31454.1 - 0.18 11.6 5.2 0.2 11.5 4.6 1.4 1 1 0 1 1 1 0 Nsp1-like C-terminal region DNA_mis_repair PF01119.19 EEQ31455.1 - 1.6e-20 72.9 0.1 3.1e-19 68.8 0.0 2.9 4 0 0 4 4 4 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EEQ31455.1 - 3.3e-19 69.1 3.0 4.2e-16 59.0 2.0 3.0 2 1 0 2 2 2 2 MutL C terminal dimerisation domain Serinc PF03348.15 EEQ31456.1 - 3.4e-162 540.3 13.5 3.8e-162 540.1 13.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF4148 PF13663.6 EEQ31456.1 - 2.2 8.5 6.6 0.35 11.1 1.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Nodulin-like PF06813.13 EEQ31457.1 - 4e-20 72.4 4.4 8.8e-20 71.2 4.4 1.5 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 EEQ31457.1 - 6.7e-10 38.4 31.0 3.3e-07 29.6 31.0 3.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DivIVA PF05103.13 EEQ31458.1 - 0.0011 19.0 2.8 0.0011 19.0 2.8 1.6 2 0 0 2 2 2 1 DivIVA protein Pox_A_type_inc PF04508.12 EEQ31458.1 - 0.021 14.6 4.5 0.24 11.3 2.7 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF3461 PF11944.8 EEQ31458.1 - 0.05 13.7 0.2 0.08 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) CENP-F_N PF10481.9 EEQ31458.1 - 0.068 12.8 5.8 2.1 7.9 0.1 2.4 1 1 1 2 2 2 0 Cenp-F N-terminal domain Med4 PF10018.9 EEQ31458.1 - 0.14 11.8 5.3 0.032 13.9 1.8 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DASH_Spc19 PF08287.11 EEQ31458.1 - 0.61 10.0 12.0 0.021 14.7 5.4 1.9 2 0 0 2 2 2 0 Spc19 JIP_LZII PF16471.5 EEQ31458.1 - 7.9 6.7 8.2 23 5.3 8.2 1.7 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II PI3_PI4_kinase PF00454.27 EEQ31459.1 - 1.2e-45 156.3 0.0 2.1e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1658 PF07871.11 EEQ31459.1 - 0.071 13.1 2.6 14 5.9 1.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) SNF2_N PF00176.23 EEQ31460.1 - 2.6e-68 230.3 0.1 3.8e-68 229.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ31460.1 - 3.8e-12 46.5 0.0 1.1e-11 45.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ31460.1 - 1.8e-06 27.8 0.0 4.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EEQ31460.1 - 2.4e-05 24.4 0.0 8.1e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HIRAN PF08797.11 EEQ31460.1 - 0.079 12.9 0.0 0.28 11.2 0.0 1.9 1 1 0 1 1 1 0 HIRAN domain PyrI_C PF02748.15 EEQ31460.1 - 0.089 12.7 0.5 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Prok-RING_4 PF14447.6 EEQ31460.1 - 0.097 12.6 2.0 0.2 11.5 2.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Med21 PF11221.8 EEQ31461.1 - 1.6e-50 171.1 17.5 6.5e-49 165.9 17.5 2.0 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.10 EEQ31461.1 - 0.034 14.3 0.2 0.067 13.3 0.2 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Spt20 PF12090.8 EEQ31461.1 - 0.4 10.3 8.2 0.47 10.0 8.2 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 EEQ31461.1 - 0.65 9.9 11.0 0.71 9.8 11.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med9 PF07544.13 EEQ31461.1 - 7.9 6.7 11.2 0.077 13.1 2.2 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2034 PF10356.9 EEQ31462.1 - 3e-37 127.9 0.0 8.2e-21 74.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EEQ31462.1 - 1.7e-07 31.3 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease DUF3431 PF11913.8 EEQ31463.1 - 1.1e-66 224.7 0.0 3.4e-64 216.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) MbtH PF03621.13 EEQ31463.1 - 0.045 13.2 0.0 0.22 11.0 0.1 2.0 2 0 0 2 2 2 0 MbtH-like protein Spc24 PF08286.11 EEQ31464.1 - 6.2e-39 132.5 3.9 1.7e-37 127.8 0.2 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 WXG100 PF06013.12 EEQ31464.1 - 0.014 15.6 1.6 0.3 11.4 0.1 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Spc7 PF08317.11 EEQ31464.1 - 0.015 14.2 8.9 0.021 13.7 8.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MAP65_ASE1 PF03999.12 EEQ31464.1 - 0.018 13.8 5.1 0.023 13.4 5.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) APG6_N PF17675.1 EEQ31464.1 - 0.021 15.4 12.9 0.03 14.9 12.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3584 PF12128.8 EEQ31464.1 - 0.023 12.3 8.0 0.028 11.9 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4795 PF16043.5 EEQ31464.1 - 0.045 13.4 4.8 0.28 10.8 4.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) FlaC_arch PF05377.11 EEQ31464.1 - 0.069 13.6 5.8 0.79 10.2 0.2 2.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF4472 PF14739.6 EEQ31464.1 - 0.086 13.6 1.8 0.086 13.6 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF4337 PF14235.6 EEQ31464.1 - 0.095 12.8 3.2 0.13 12.4 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) FlxA PF14282.6 EEQ31464.1 - 0.11 12.5 3.5 7 6.7 0.1 2.2 2 0 0 2 2 2 0 FlxA-like protein CLZ PF16526.5 EEQ31464.1 - 0.11 12.9 10.4 0.3 11.5 1.8 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels V_ATPase_I PF01496.19 EEQ31464.1 - 0.14 10.1 1.4 0.14 10.0 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 EEQ31464.1 - 0.18 10.3 2.5 0.21 10.1 2.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 EEQ31464.1 - 0.2 11.6 7.3 1.1 9.3 1.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF5344 PF17279.2 EEQ31464.1 - 0.28 11.8 2.5 4.1 8.0 0.2 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5344) DHR10 PF18595.1 EEQ31464.1 - 0.35 11.0 14.1 1.4 9.0 5.4 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Swi5 PF07061.11 EEQ31464.1 - 0.8 9.8 4.1 11 6.1 0.3 2.4 2 0 0 2 2 2 0 Swi5 TPR_MLP1_2 PF07926.12 EEQ31464.1 - 0.82 9.7 13.0 0.32 11.1 3.0 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Csm1_N PF18504.1 EEQ31464.1 - 0.85 10.0 7.3 3.3 8.1 0.9 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain YlqD PF11068.8 EEQ31464.1 - 0.87 10.0 4.3 1.4 9.3 4.3 1.4 1 0 0 1 1 1 0 YlqD protein YabA PF06156.13 EEQ31464.1 - 0.89 10.2 4.8 16 6.2 0.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Phage_GPO PF05929.11 EEQ31464.1 - 1 8.9 5.7 3.5 7.2 5.7 1.8 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Ribosomal_L29 PF00831.23 EEQ31464.1 - 1.1 9.2 8.2 1.5 8.9 0.8 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein SlyX PF04102.12 EEQ31464.1 - 1.9 9.1 6.7 5.7 7.6 0.8 2.5 2 1 0 2 2 2 0 SlyX Rx_N PF18052.1 EEQ31464.1 - 2.1 8.7 7.8 3.8 7.8 0.6 2.2 1 1 1 2 2 2 0 Rx N-terminal domain DUF4140 PF13600.6 EEQ31464.1 - 3.7 8.1 8.4 15 6.1 2.7 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Syntaxin-6_N PF09177.11 EEQ31464.1 - 4.4 7.9 7.4 9 6.9 1.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DASH_Dam1 PF08653.10 EEQ31464.1 - 9.1 6.2 6.6 23 4.9 0.6 3.4 2 1 2 4 4 4 0 DASH complex subunit Dam1 Fis1_TPR_C PF14853.6 EEQ31465.1 - 1e-25 89.5 0.4 1.7e-25 88.8 0.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EEQ31465.1 - 7.2e-17 60.8 0.0 1.1e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EEQ31465.1 - 0.001 19.0 1.6 0.0025 17.8 1.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ31465.1 - 0.11 12.4 2.4 0.25 11.2 2.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Podoplanin PF05808.11 EEQ31465.1 - 0.21 11.7 0.2 0.28 11.3 0.2 1.2 1 0 0 1 1 1 0 Podoplanin zf-RING_2 PF13639.6 EEQ31466.1 - 2e-13 50.4 20.4 4.1e-13 49.4 8.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EEQ31466.1 - 1.2e-11 44.1 3.1 1.2e-11 44.1 3.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EEQ31466.1 - 1.4e-09 37.6 8.6 1.4e-09 37.6 8.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ31466.1 - 1.4e-08 34.4 10.7 7.7e-07 28.9 3.4 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ31466.1 - 3.5e-07 30.0 17.3 7.6e-07 28.9 7.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ31466.1 - 7.7e-07 29.3 7.5 7.7e-07 29.3 7.5 2.5 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EEQ31466.1 - 1.2e-06 28.3 5.6 1.2e-06 28.3 5.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zinc_ribbon_9 PF14369.6 EEQ31466.1 - 3.1e-06 27.3 10.7 0.00033 20.9 5.7 2.6 2 0 0 2 2 2 2 zinc-ribbon Prok-RING_4 PF14447.6 EEQ31466.1 - 3.6e-05 23.5 13.6 0.00046 20.0 4.6 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EEQ31466.1 - 8.6e-05 22.5 9.6 0.00021 21.3 3.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EEQ31466.1 - 0.00056 19.9 2.8 0.00056 19.9 2.8 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 EEQ31466.1 - 0.0013 18.7 0.7 0.0013 18.7 0.7 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EEQ31466.1 - 0.0096 15.9 7.2 0.064 13.3 0.4 2.5 2 0 0 2 2 2 1 Double zinc ribbon zf-C3HC4_4 PF15227.6 EEQ31466.1 - 0.23 11.6 13.5 2.8 8.2 1.1 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EEQ31466.1 - 0.95 9.3 13.9 0.37 10.6 4.3 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 EEQ31466.1 - 2 8.5 10.0 1.5 8.8 0.6 2.5 2 1 0 2 2 2 0 zinc-ribbons zf-UDP PF14569.6 EEQ31466.1 - 2 8.6 8.8 3.7 7.7 0.6 2.6 2 1 0 2 2 2 0 Zinc-binding RING-finger Baculo_RING PF05883.11 EEQ31466.1 - 2 8.4 4.9 1.1 9.2 0.3 2.5 2 1 1 3 3 3 0 Baculovirus U-box/Ring-like domain Zn_ribbon_17 PF17120.5 EEQ31466.1 - 2.9 7.6 14.6 0.044 13.4 6.6 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EEQ31466.1 - 5 7.4 10.4 2.8 8.2 6.6 2.6 2 1 0 2 2 1 0 FANCL C-terminal domain UPF0547 PF10571.9 EEQ31466.1 - 6.7 6.9 10.5 4.6 7.4 0.4 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 PhnA_Zn_Ribbon PF08274.12 EEQ31466.1 - 6.7 6.8 9.3 12 5.9 0.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Aminotran_5 PF00266.19 EEQ31467.1 - 4.1e-22 78.6 0.0 5.9e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EEQ31467.1 - 4.2e-05 22.9 0.0 5.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEQ31467.1 - 0.016 13.8 0.0 0.024 13.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_trans_1_2 PF13524.6 EEQ31469.1 - 0.032 14.6 0.1 0.088 13.2 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 APH PF01636.23 EEQ31471.1 - 2.7e-15 56.9 0.0 7.2e-15 55.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ31471.1 - 2e-06 27.3 0.0 0.48 9.7 0.0 3.2 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEQ31471.1 - 0.021 14.4 0.0 0.89 9.1 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF1679 PF07914.11 EEQ31471.1 - 0.12 11.3 0.0 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) ADH_zinc_N PF00107.26 EEQ31472.1 - 5.9e-22 78.0 0.7 8.9e-22 77.5 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ31472.1 - 6.8e-08 33.6 0.0 1.3e-07 32.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ31472.1 - 0.0089 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GAD PF02938.14 EEQ31472.1 - 0.025 14.8 0.2 0.071 13.3 0.0 1.8 2 0 0 2 2 2 0 GAD domain AlaDh_PNT_C PF01262.21 EEQ31472.1 - 0.082 12.2 1.1 0.15 11.4 1.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EEQ31472.1 - 0.11 11.9 1.7 0.18 11.3 0.7 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Sars6 PF12133.8 EEQ31474.1 - 0.18 11.7 0.2 0.32 11.0 0.2 1.3 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus Trp_syntA PF00290.20 EEQ31476.1 - 2e-93 312.0 0.1 4e-93 311.0 0.1 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EEQ31476.1 - 3.4e-48 164.6 1.7 5.5e-48 163.9 1.7 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Gram_pos_anchor PF00746.21 EEQ31477.1 - 0.051 13.5 0.2 0.099 12.6 0.2 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Adeno_E3_CR2 PF02439.15 EEQ31477.1 - 0.077 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EEQ31477.1 - 0.28 10.6 3.3 0.62 9.5 3.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ATP-synt_ab PF00006.25 EEQ31478.1 - 6.9e-68 228.5 0.0 1e-67 227.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EEQ31478.1 - 3.5e-12 46.7 0.7 7.3e-12 45.6 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_S10 PF00450.22 EEQ31479.1 - 5.3e-68 230.3 0.0 1.1e-67 229.4 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Ubiq-Cytc-red_N PF09165.10 EEQ31479.1 - 1 10.3 0.1 1 10.3 0.1 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal DUF2180 PF09947.9 EEQ31480.1 - 0.038 14.0 0.5 0.092 12.7 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) IBR PF01485.21 EEQ31482.1 - 2.6e-07 30.7 22.2 7.4e-07 29.3 5.5 3.3 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EEQ31482.1 - 0.0012 18.7 2.7 0.0012 18.7 2.7 3.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ31482.1 - 0.026 14.5 5.7 0.026 14.5 5.7 2.5 2 1 0 2 2 2 0 RING-type zinc-finger CCDC50_N PF15295.6 EEQ31482.1 - 0.061 13.5 4.1 0.66 10.2 0.2 2.3 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus Dynamin_M PF01031.20 EEQ31483.1 - 1.4e-28 99.9 0.2 7.4e-21 74.6 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 EEQ31483.1 - 5.3e-16 59.1 0.1 1.3e-15 57.9 0.1 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EEQ31483.1 - 0.079 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Bacillus_HBL PF05791.11 EEQ31483.1 - 0.095 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) GED PF02212.18 EEQ31483.1 - 0.1 12.8 0.3 0.77 10.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin GTPase effector domain Usp PF00582.26 EEQ31486.1 - 5.7e-08 33.4 2.6 0.0015 19.1 0.0 3.0 3 1 0 3 3 3 2 Universal stress protein family MAP65_ASE1 PF03999.12 EEQ31486.1 - 4.2 6.0 12.2 1.2 7.7 8.7 1.9 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) DnaJ PF00226.31 EEQ31487.1 - 7.3e-24 83.7 2.3 2e-23 82.3 2.3 1.8 1 0 0 1 1 1 1 DnaJ domain DUF493 PF04359.14 EEQ31487.1 - 0.15 12.6 0.1 0.36 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF493) Stm1_N PF09598.10 EEQ31487.1 - 0.97 10.3 10.5 1.2 10.1 4.2 3.0 3 0 0 3 3 3 0 Stm1 HAD_2 PF13419.6 EEQ31488.1 - 2.5e-26 92.8 0.0 3e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ31488.1 - 3e-13 50.5 0.1 2.7e-11 44.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ31488.1 - 2.3e-10 40.4 0.0 5.6e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 EEQ31488.1 - 1.6e-08 35.1 0.2 3.4e-08 34.1 0.2 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EEQ31488.1 - 8.2e-05 22.7 0.0 0.024 14.7 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEQ31488.1 - 0.027 14.2 0.1 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EEQ31488.1 - 0.094 12.3 0.0 0.25 10.9 0.0 1.8 2 1 0 2 2 2 0 Mitochondrial PGP phosphatase PNK3P PF08645.11 EEQ31488.1 - 0.18 11.5 0.1 19 4.9 0.0 2.7 2 1 1 3 3 3 0 Polynucleotide kinase 3 phosphatase Pterin_4a PF01329.19 EEQ31489.1 - 2.7e-21 75.5 0.1 2.2e-18 66.2 0.1 2.4 1 1 1 2 2 2 2 Pterin 4 alpha carbinolamine dehydratase UPRTase PF14681.6 EEQ31489.1 - 9.1e-15 54.6 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EEQ31489.1 - 1.3e-05 24.8 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MFS_1 PF07690.16 EEQ31490.1 - 3.7e-38 131.4 72.5 9.8e-28 97.1 38.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ31490.1 - 4e-08 32.6 31.4 0.00043 19.3 14.6 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter SidC_N PF18219.1 EEQ31491.1 - 0.068 12.1 0.0 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 SidC N-terminal domain Pkinase PF00069.25 EEQ31495.1 - 2.5e-55 187.7 0.0 4.3e-55 186.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31495.1 - 5.7e-28 97.9 0.0 4.1e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ31495.1 - 0.0011 18.0 1.8 0.0012 17.9 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EEQ31495.1 - 0.077 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.7 EEQ31497.1 - 1.1e-18 67.5 4.5 2.1e-18 66.6 4.5 1.5 1 0 0 1 1 1 1 Stc1 domain His_Me_b4a2 PF18275.1 EEQ31497.1 - 1.9 8.6 13.6 2.2 8.4 0.0 3.2 3 1 0 3 3 3 0 His-Me finger endonuclease beta4-alpha2 domain zf-met PF12874.7 EEQ31497.1 - 9.4 6.8 8.3 21 5.6 2.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type APH PF01636.23 EEQ31498.1 - 2.3e-13 50.7 0.0 1.8e-12 47.7 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EEQ31498.1 - 0.067 12.5 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase Cas_Cmr3 PF09700.10 EEQ31499.1 - 0.071 12.5 0.0 0.087 12.2 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) TPR_12 PF13424.6 EEQ31500.1 - 1.2e-16 60.8 1.1 0.00062 20.0 0.0 4.5 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ31500.1 - 4.3e-05 23.2 0.1 0.81 9.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ31500.1 - 0.00031 20.6 0.4 13 6.2 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ31500.1 - 0.0019 18.0 0.8 3.8 7.5 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ31500.1 - 0.0036 17.2 2.1 1.3 9.2 0.0 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 EEQ31500.1 - 0.0067 16.6 2.5 18 5.8 0.0 3.7 3 0 0 3 3 3 1 PPR repeat TPR_19 PF14559.6 EEQ31500.1 - 0.0079 16.7 0.2 59 4.3 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat YjeJ PF15922.5 EEQ31502.1 - 0.026 13.8 0.6 0.034 13.4 0.6 1.1 1 0 0 1 1 1 0 YjeJ-like TnpB_IS66 PF05717.13 EEQ31502.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 IS66 Orf2 like protein Abhydrolase_1 PF00561.20 EEQ31504.1 - 1.7e-09 37.8 0.0 1e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ31504.1 - 0.00012 22.8 1.4 0.00022 21.9 1.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family TLP1_add_C PF18313.1 EEQ31505.1 - 0.095 12.7 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain Stn1 PF10451.9 EEQ31508.1 - 2e-13 49.9 0.8 4.9e-11 42.1 0.8 2.1 1 1 0 1 1 1 1 Telomere regulation protein Stn1 DUF3403 PF11883.8 EEQ31509.1 - 1.7 8.8 4.6 2.9 8.1 1.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3403) Inv-AAD PF18785.1 EEQ31510.1 - 3.3e-45 153.1 0.1 6.1e-45 152.2 0.1 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EEQ31510.1 - 1e-09 38.1 0.0 9.8e-09 35.0 0.0 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EEQ31510.1 - 2.2e-05 24.4 0.1 4.4e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 EEQ31510.1 - 0.025 14.7 0.1 0.065 13.4 0.1 1.7 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 EEQ31510.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 Metallophos PF00149.28 EEQ31511.1 - 2.7e-09 37.8 0.2 3.9e-09 37.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AbiEii PF08843.11 EEQ31512.1 - 0.00046 20.2 0.0 0.00081 19.4 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system RNase_PH PF01138.21 EEQ31514.1 - 4e-12 46.8 0.0 8.5e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 TGF_beta_GS PF08515.12 EEQ31514.1 - 2.2 7.8 4.7 2.8 7.5 0.7 2.4 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif DUF3914 PF13053.6 EEQ31515.1 - 0.11 12.8 0.1 18 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3914) Baculo_PEP_C PF04513.12 EEQ31518.1 - 0.28 11.2 6.5 0.82 9.7 0.7 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_A_bac PF01000.26 EEQ31519.1 - 9.9e-31 106.4 0.0 1.6e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EEQ31519.1 - 4.9e-15 54.7 0.0 7e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain eIF-4B PF06273.11 EEQ31519.1 - 2.6 7.0 4.1 3.5 6.6 4.1 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Pkinase PF00069.25 EEQ31520.1 - 2e-18 66.7 0.0 6.2e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Flu_M2 PF00599.17 EEQ31521.1 - 0.17 12.0 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Pkinase PF00069.25 EEQ31522.1 - 1.1e-30 106.9 0.0 1.6e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31522.1 - 8.8e-15 54.7 0.0 2.2e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ31522.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family NUDIX PF00293.28 EEQ31523.1 - 7.2e-19 68.1 0.4 8.6e-19 67.9 0.4 1.0 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.15 EEQ31524.1 - 1.1e-42 145.8 2.2 1.9e-42 145.1 2.2 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EEQ31524.1 - 2.3e-22 79.2 6.3 4.6e-22 78.2 6.3 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Transp_cyt_pur PF02133.15 EEQ31525.1 - 3.3e-30 105.2 36.4 3.7e-29 101.8 36.4 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SRA1 PF07304.11 EEQ31526.1 - 2.1e-13 50.3 0.0 1.8e-12 47.2 0.0 2.8 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 EEQ31526.1 - 9.9e-07 28.7 0.6 3.3e-05 23.7 0.6 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 EEQ31526.1 - 1.4e-06 28.9 0.3 0.21 12.5 0.0 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Prp18 PF02840.15 EEQ31526.1 - 0.0046 17.0 0.1 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 Prp18 domain RRM_1 PF00076.22 EEQ31527.1 - 2.9e-16 59.1 0.0 4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ31527.1 - 0.036 14.2 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EEQ31527.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif COX6B PF02297.17 EEQ31528.1 - 1.2e-18 67.1 7.2 1.3e-18 66.9 7.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 EEQ31528.1 - 0.017 15.0 0.5 0.025 14.5 0.5 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain T2SSJ PF11612.8 EEQ31528.1 - 0.021 15.1 0.1 5.2 7.3 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein J CX9C PF16860.5 EEQ31528.1 - 0.026 14.5 3.1 0.042 13.9 3.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ketoacyl-synt PF00109.26 EEQ31528.1 - 0.06 12.9 0.0 0.06 12.9 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Mito_carr PF00153.27 EEQ31529.1 - 1.6e-52 175.4 0.1 1.7e-17 63.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.20 EEQ31530.1 - 6.9e-47 160.0 0.1 3.9e-26 92.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EEQ31530.1 - 5.4e-28 97.3 0.0 1.6e-27 95.8 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 EEQ31531.1 - 4.1e-42 143.7 2.9 5.9e-42 143.2 2.9 1.2 1 0 0 1 1 1 1 GrpE PEARLI-4 PF05278.12 EEQ31531.1 - 0.033 13.8 1.3 0.056 13.0 1.3 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) RrnaAD PF00398.20 EEQ31531.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Coatomer_g_Cpla PF16381.5 EEQ31531.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform Spc7 PF08317.11 EEQ31531.1 - 0.23 10.3 6.2 0.29 10.0 5.7 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Erythro-docking PF09277.11 EEQ31531.1 - 0.25 11.3 0.2 0.25 11.3 0.2 2.4 3 0 0 3 3 3 0 Erythronolide synthase, docking HIP1_clath_bdg PF16515.5 EEQ31531.1 - 0.72 10.5 6.7 3.9 8.1 4.1 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HSCB_C PF07743.13 EEQ31531.1 - 2.1 8.9 8.7 0.86 10.1 2.6 2.4 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Uds1 PF15456.6 EEQ31532.1 - 2.8e-28 98.7 3.7 2.8e-28 98.7 3.7 1.8 2 0 0 2 2 2 1 Up-regulated During Septation Stathmin PF00836.19 EEQ31532.1 - 0.011 15.7 1.1 0.03 14.3 0.2 2.1 2 0 0 2 2 2 0 Stathmin family Seryl_tRNA_N PF02403.22 EEQ31532.1 - 0.33 11.2 1.5 37 4.6 0.0 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Calcipressin PF04847.12 EEQ31536.1 - 3.2e-35 121.6 0.1 5e-35 120.9 0.1 1.3 1 0 0 1 1 1 1 Calcipressin Pex14_N PF04695.13 EEQ31537.1 - 2.1e-42 145.4 2.8 2.1e-42 145.4 2.8 2.7 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sigma70_ECF PF07638.11 EEQ31537.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 ECF sigma factor PAPA-1 PF04795.12 EEQ31538.1 - 6e-27 94.3 8.5 6e-27 94.3 8.5 3.2 4 1 0 4 4 4 1 PAPA-1-like conserved region BUD22 PF09073.10 EEQ31538.1 - 1.4 8.2 29.2 0.08 12.3 19.7 2.1 2 0 0 2 2 2 0 BUD22 Mus7 PF09462.10 EEQ31539.1 - 1.8e-150 502.7 0.3 3.5e-150 501.8 0.3 1.5 1 0 0 1 1 1 1 Mus7/MMS22 family DUF4050 PF13259.6 EEQ31540.1 - 2.6e-55 187.6 1.5 4.8e-55 186.7 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) CorA PF01544.18 EEQ31541.1 - 6.9e-11 42.0 1.8 2.6e-09 36.8 1.8 2.1 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein PPTA PF01239.22 EEQ31541.1 - 0.11 12.2 1.0 0.31 10.8 0.2 2.2 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Ank_2 PF12796.7 EEQ31542.1 - 1.7e-24 86.2 0.0 3e-11 43.7 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ31542.1 - 1.7e-19 69.9 0.0 7.8e-12 45.5 0.1 4.0 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EEQ31542.1 - 1.8e-18 66.1 1.0 1.3e-05 25.4 0.0 5.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EEQ31542.1 - 4.8e-18 63.4 0.4 5.6e-06 26.3 0.0 6.1 6 0 0 6 6 5 3 Ankyrin repeat Ank_5 PF13857.6 EEQ31542.1 - 1.8e-15 56.8 0.8 2.5e-07 30.8 0.1 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 EEQ31542.1 - 1.8e-13 50.3 0.0 3.4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 EEQ31542.1 - 1.9e-08 34.4 0.0 5.3e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EEQ31542.1 - 0.0039 17.5 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EEQ31542.1 - 0.03 13.6 0.0 0.066 12.4 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.22 EEQ31542.1 - 0.049 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF454 PF04304.13 EEQ31542.1 - 0.1 12.6 0.1 9.1 6.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF454) HlyIII PF03006.20 EEQ31543.1 - 1.3e-37 129.7 15.1 1.7e-37 129.3 15.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related APH PF01636.23 EEQ31544.1 - 1.1e-13 51.7 0.0 3.8e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ycf4 PF02392.16 EEQ31546.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Ycf4 APH PF01636.23 EEQ31547.1 - 0.00015 21.8 0.0 0.00087 19.3 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ31547.1 - 0.12 11.2 0.0 0.3 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 EEQ31548.1 - 3e-19 69.4 0.2 9.1e-19 67.8 0.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31548.1 - 5.2e-11 42.3 0.0 2.2e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EEQ31548.1 - 0.024 13.6 0.3 0.18 10.8 0.1 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 EEQ31548.1 - 0.097 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase AAA PF00004.29 EEQ31549.1 - 8.1e-39 133.1 0.0 1.1e-37 129.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ31549.1 - 4.8e-09 35.9 0.2 1.2e-08 34.6 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EEQ31549.1 - 7.7e-05 23.1 1.8 0.0011 19.4 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EEQ31549.1 - 0.00014 21.6 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ31549.1 - 0.00019 21.7 0.1 0.018 15.3 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EEQ31549.1 - 0.00027 21.1 0.0 0.0037 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EEQ31549.1 - 0.0004 19.7 0.0 0.00083 18.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EEQ31549.1 - 0.00096 19.2 0.0 0.0031 17.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EEQ31549.1 - 0.0045 16.4 0.1 0.0099 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EEQ31549.1 - 0.012 15.6 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EEQ31549.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EEQ31549.1 - 0.023 15.1 0.0 0.064 13.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EEQ31549.1 - 0.029 14.1 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EEQ31549.1 - 0.032 14.5 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EEQ31549.1 - 0.065 12.6 0.0 0.31 10.4 0.0 2.0 3 0 0 3 3 3 0 Bacterial TniB protein AAA_17 PF13207.6 EEQ31549.1 - 0.069 13.6 0.1 0.25 11.8 0.1 2.0 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EEQ31549.1 - 0.073 13.1 0.1 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EEQ31549.1 - 0.092 12.4 0.1 2.2 7.9 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 EEQ31549.1 - 0.093 13.3 0.0 0.093 13.3 0.0 2.4 3 0 0 3 3 1 0 AAA domain NACHT PF05729.12 EEQ31549.1 - 0.14 12.0 0.2 0.42 10.5 0.1 1.8 2 0 0 2 2 2 0 NACHT domain IPT PF01745.16 EEQ31549.1 - 0.16 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase Ribosomal_60s PF00428.19 EEQ31549.1 - 4.2 8.0 8.2 2 9.1 0.7 3.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein LIM_bind PF01803.16 EEQ31550.1 - 1.3e-47 162.4 0.0 1.3e-47 162.4 0.0 4.1 3 1 1 4 4 4 1 LIM-domain binding protein cobW PF02492.19 EEQ31551.1 - 2.9e-33 114.9 0.0 3.6e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EEQ31551.1 - 5.4e-06 25.6 0.0 0.0072 15.3 0.0 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EEQ31551.1 - 0.0046 17.0 0.0 0.016 15.3 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EEQ31551.1 - 0.0051 17.3 0.0 0.0073 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EEQ31551.1 - 0.035 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 EEQ31551.1 - 0.071 13.2 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 EEQ31551.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 EEQ31551.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 EEQ31551.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit BING4CT PF08149.11 EEQ31552.1 - 6.1e-40 134.9 0.5 1.6e-35 120.8 0.0 3.6 4 0 0 4 4 4 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EEQ31552.1 - 2.1e-09 37.6 0.1 1.2 9.5 0.0 6.3 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ31552.1 - 5.6e-06 27.0 0.1 0.55 11.2 0.0 4.5 4 1 1 5 5 5 2 WD domain, G-beta repeat DUF4427 PF14468.6 EEQ31552.1 - 0.058 13.5 1.4 0.25 11.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4427) CHASE3 PF05227.13 EEQ31552.1 - 1.6 8.6 10.4 0.11 12.4 4.9 1.9 2 0 0 2 2 2 0 CHASE3 domain RIBIOP_C PF04950.12 EEQ31553.1 - 1.7e-104 349.4 0.0 6.5e-104 347.4 0.0 1.9 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EEQ31553.1 - 2.5e-13 49.9 0.0 6e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain HlyIII PF03006.20 EEQ31554.1 - 5.3e-56 189.8 17.3 6.5e-56 189.5 17.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related OAD_gamma PF04277.13 EEQ31554.1 - 0.15 12.7 0.6 7.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF726 PF05277.12 EEQ31555.1 - 3.7e-121 404.2 0.6 5.2e-121 403.8 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glu-tRNAGln PF02686.15 EEQ31555.1 - 6.1e-10 39.3 0.1 1.9e-09 37.6 0.1 2.0 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Thioesterase PF00975.20 EEQ31555.1 - 0.0019 18.3 0.5 0.011 15.9 0.0 2.4 3 0 0 3 3 3 1 Thioesterase domain Phage_holin_3_6 PF07332.11 EEQ31555.1 - 0.075 13.1 3.7 0.27 11.3 3.7 2.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III SNAP PF14938.6 EEQ31556.1 - 5.9e-106 354.0 18.8 7.4e-106 353.7 18.8 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EEQ31556.1 - 1.3e-06 28.6 7.4 0.0062 16.8 0.3 3.8 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ31556.1 - 0.0031 17.5 13.1 9.6 6.6 0.6 6.1 3 2 2 6 6 6 2 Tetratricopeptide repeat IL13 PF03487.13 EEQ31556.1 - 0.043 13.6 0.2 0.08 12.7 0.2 1.4 1 0 0 1 1 1 0 Interleukin-13 TPR_6 PF13174.6 EEQ31556.1 - 0.26 12.0 12.8 14 6.6 0.1 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 EEQ31556.1 - 3.4 8.8 20.0 1.9 9.6 0.2 6.2 7 0 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.6 EEQ31556.1 - 4.4 7.8 18.0 6 7.3 0.1 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat AAA PF00004.29 EEQ31557.1 - 0.0016 18.8 0.0 0.0042 17.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 EEQ31557.1 - 0.0023 16.9 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain NB-ARC PF00931.22 EEQ31557.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ClpB_D2-small PF10431.9 EEQ31557.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein Ank_2 PF12796.7 EEQ31557.1 - 0.024 15.2 0.3 0.38 11.4 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) AAA_18 PF13238.6 EEQ31557.1 - 0.025 15.1 0.1 0.16 12.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EEQ31557.1 - 0.028 14.8 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain AAA_24 PF13479.6 EEQ31557.1 - 0.037 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EEQ31557.1 - 0.064 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EEQ31557.1 - 0.068 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EEQ31557.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase zf_CCCH_4 PF18345.1 EEQ31557.1 - 0.72 10.0 3.2 3.4 7.9 3.2 2.1 1 1 0 1 1 1 0 Zinc finger domain DUF4434 PF14488.6 EEQ31559.1 - 0.18 11.8 0.1 0.26 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Antimicrobial12 PF08107.11 EEQ31559.1 - 0.34 10.7 3.5 0.18 11.6 0.9 1.8 2 0 0 2 2 2 0 Pleurocidin family zf-dskA_traR PF01258.17 EEQ31559.1 - 2.5 8.1 13.8 0.55 10.2 0.5 2.8 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Cupin_1 PF00190.22 EEQ31560.1 - 5.2e-33 113.8 0.0 9.9e-18 64.2 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EEQ31560.1 - 3e-18 65.3 0.8 6e-10 38.7 0.2 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EEQ31560.1 - 0.00017 21.2 0.1 0.15 11.8 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF861) PH PF00169.29 EEQ31563.1 - 0.18 12.3 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 PH domain Sec62 PF03839.16 EEQ31564.1 - 9.1e-73 244.3 0.9 9.1e-73 244.3 0.9 2.1 2 0 0 2 2 2 1 Translocation protein Sec62 Zip PF02535.22 EEQ31564.1 - 0.003 16.8 0.9 1.6 7.9 2.4 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter DDHD PF02862.17 EEQ31564.1 - 0.02 15.0 5.2 0.12 12.5 3.6 2.1 2 0 0 2 2 2 0 DDHD domain Velvet PF11754.8 EEQ31564.1 - 0.027 14.4 7.3 0.4 10.6 4.0 2.2 2 0 0 2 2 2 0 Velvet factor DUF4254 PF14063.6 EEQ31564.1 - 0.036 13.9 6.4 0.078 12.8 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) MPM1 PF17234.2 EEQ31564.1 - 0.076 13.3 9.1 6.2 7.1 7.1 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Ribosomal_L20 PF00453.18 EEQ31564.1 - 0.21 11.7 4.5 1.1 9.4 1.0 2.7 3 0 0 3 3 2 0 Ribosomal protein L20 V_ATPase_I PF01496.19 EEQ31564.1 - 0.22 9.4 5.5 0.37 8.7 5.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ipi1_N PF12333.8 EEQ31564.1 - 0.68 10.6 3.9 2.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Peroxin-3 PF04882.12 EEQ31564.1 - 0.71 8.8 10.0 19 4.1 0.0 2.1 2 0 0 2 2 2 0 Peroxin-3 DUF4834 PF16118.5 EEQ31564.1 - 1.9 9.5 14.7 16 6.5 0.0 2.6 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) SpoIIP PF07454.11 EEQ31564.1 - 2 7.8 12.6 0.078 12.4 5.2 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) EPL1 PF10513.9 EEQ31564.1 - 3.1 8.2 12.3 0.077 13.4 3.8 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Rxt3 PF08642.10 EEQ31564.1 - 8 7.2 8.6 3.8 8.3 2.2 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Gti1_Pac2 PF09729.9 EEQ31564.1 - 9.1 6.3 11.0 3.3 7.8 2.5 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Lectin_C PF00059.21 EEQ31565.1 - 0.00015 22.5 2.5 0.00017 22.3 1.2 1.8 2 0 0 2 2 2 1 Lectin C-type domain DUF3446 PF11928.8 EEQ31565.1 - 5.4 7.4 9.9 0.18 12.1 1.7 2.6 3 0 0 3 3 3 0 Early growth response N-terminal domain Pyr_redox_2 PF07992.14 EEQ31566.1 - 4e-06 26.3 0.0 1.1e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ31566.1 - 0.028 14.6 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EEQ31566.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EEQ31566.1 - 0.19 10.4 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF2046 PF09755.9 EEQ31567.1 - 0.0028 16.9 2.7 0.0041 16.4 0.6 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) TMCO5 PF14992.6 EEQ31567.1 - 0.047 13.3 0.0 0.097 12.2 0.0 1.6 1 1 0 1 1 1 0 TMCO5 family Cnn_1N PF07989.11 EEQ31567.1 - 0.13 12.5 2.5 0.48 10.6 0.0 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 EEQ31567.1 - 0.19 11.9 4.5 12 6.1 1.8 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 EEQ31567.1 - 0.7 10.6 11.5 0.58 10.8 0.2 2.5 2 0 0 2 2 2 0 SlyX DUF2968 PF11180.8 EEQ31567.1 - 2.7 7.6 13.2 0.3 10.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Carn_acyltransf PF00755.20 EEQ31568.1 - 5.5e-206 685.7 0.0 6.3e-206 685.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.10 EEQ31569.1 - 2.1e-46 157.8 0.9 1.6e-45 155.0 0.0 2.8 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EEQ31569.1 - 0.00012 22.1 0.0 0.0016 18.5 0.0 2.3 2 0 0 2 2 2 1 LCCL domain CLN3 PF02487.17 EEQ31572.1 - 4.6e-161 536.3 1.6 5.3e-161 536.1 1.6 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EEQ31572.1 - 1.3e-06 27.6 2.5 1.3e-06 27.6 2.5 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 EEQ31573.1 - 4.9e-34 118.0 0.0 1.4e-23 83.8 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 EEQ31573.1 - 0.067 13.0 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Aminotran_3 PF00202.21 EEQ31574.1 - 9.4e-105 350.6 0.0 1.5e-104 349.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EEQ31574.1 - 6.7e-05 22.2 0.0 0.0002 20.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DUF1674 PF07896.12 EEQ31575.1 - 4.9e-19 68.6 4.5 4.9e-19 68.6 4.5 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) HMGL-like PF00682.19 EEQ31576.1 - 9e-44 150.0 0.0 1.1e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 HMGL-like PE PF00934.20 EEQ31576.1 - 0.11 12.8 0.5 0.41 11.0 0.5 2.0 1 1 0 1 1 1 0 PE family Diphthamide_syn PF01866.17 EEQ31577.1 - 3.2e-118 394.6 0.0 4.2e-118 394.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Bromodomain PF00439.25 EEQ31578.1 - 1.3e-06 28.4 0.0 0.00021 21.3 0.0 2.4 2 0 0 2 2 2 2 Bromodomain OSCP PF00213.18 EEQ31580.1 - 3.9e-45 154.1 2.2 5.2e-45 153.6 2.2 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Mob1_phocein PF03637.17 EEQ31581.1 - 3.1e-73 245.3 0.1 3.9e-73 245.0 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Rgp1 PF08737.10 EEQ31582.1 - 1.3e-128 429.8 0.0 2.4e-128 428.9 0.0 1.5 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 EEQ31582.1 - 2.4e-05 24.4 0.0 5.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EEQ31582.1 - 0.016 15.7 2.3 0.58 10.6 0.0 3.5 4 1 0 4 4 4 0 Arrestin (or S-antigen), C-terminal domain Neugrin PF06413.11 EEQ31583.1 - 5.2e-10 39.7 1.1 9e-10 38.9 1.1 1.5 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 EEQ31583.1 - 1.7e-06 28.3 13.2 5.5e-06 26.6 12.0 2.1 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_7 PF02796.15 EEQ31583.1 - 0.036 14.2 0.1 0.079 13.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_DeoR PF08220.12 EEQ31583.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Pdase_C33_assoc PF14756.6 EEQ31584.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C33-associated domain KR PF08659.10 EEQ31585.1 - 1e-63 214.5 0.3 2e-63 213.6 0.3 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EEQ31585.1 - 1.7e-53 181.8 0.0 3.3e-53 180.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EEQ31585.1 - 1e-52 179.2 0.1 1.3e-42 146.1 0.0 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EEQ31585.1 - 3.6e-44 151.5 0.2 2.9e-43 148.6 0.1 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ31585.1 - 1.3e-38 131.6 0.1 4.2e-38 130.0 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EEQ31585.1 - 1.5e-14 54.4 0.0 4.4e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EEQ31585.1 - 1.3e-13 52.1 0.0 4.6e-13 50.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EEQ31585.1 - 2.3e-08 33.7 0.0 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EEQ31585.1 - 1e-05 25.5 0.1 3.5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ31585.1 - 0.007 16.2 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.12 EEQ31585.1 - 0.02 15.6 0.0 0.057 14.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain PP-binding PF00550.25 EEQ31585.1 - 0.027 14.8 0.0 0.076 13.4 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Shikimate_DH PF01488.20 EEQ31585.1 - 0.074 13.1 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EEQ31586.1 - 4.1e-19 69.0 0.0 1.3e-18 67.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EEQ31586.1 - 0.0055 16.3 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 EEQ31586.1 - 0.0057 15.7 0.0 0.74 8.8 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.27 EEQ31586.1 - 0.0069 16.9 0.9 0.02 15.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ31586.1 - 0.074 12.3 0.1 0.54 9.4 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ketoacyl-synt PF00109.26 EEQ31587.1 - 1.2e-65 221.7 0.0 2.2e-65 220.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EEQ31587.1 - 6.1e-33 113.3 0.0 1.2e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EEQ31587.1 - 2.4e-26 92.5 0.0 3.7e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EEQ31587.1 - 2.7e-23 83.0 0.0 7.3e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 EEQ31587.1 - 9.1e-15 55.0 0.1 1.2e-10 41.6 0.0 2.8 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 EEQ31587.1 - 3.7e-09 36.8 0.7 8.5e-09 35.7 0.7 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 EEQ31587.1 - 3.3e-07 29.8 0.2 3.3e-07 29.8 0.2 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Epimerase PF01370.21 EEQ31587.1 - 1.2e-05 24.9 0.0 3.7e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 EEQ31587.1 - 6.8e-05 22.3 0.0 0.00031 20.2 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EEQ31587.1 - 0.0026 18.2 0.1 0.013 15.9 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension 3Beta_HSD PF01073.19 EEQ31587.1 - 0.023 13.7 0.0 0.57 9.1 0.0 2.5 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EEQ31587.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 KR domain ICMT PF04140.14 EEQ31588.1 - 6.8e-29 100.1 0.2 6.8e-29 100.1 0.2 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EEQ31588.1 - 4.5e-12 46.3 1.2 4.5e-12 46.3 1.2 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EEQ31588.1 - 1.1e-05 25.1 0.3 1.7e-05 24.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Tmemb_170 PF10190.9 EEQ31590.1 - 3.5e-23 82.0 9.8 3.9e-23 81.8 9.8 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF1461 PF07314.11 EEQ31590.1 - 0.061 13.2 0.5 0.096 12.6 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1461) APH PF01636.23 EEQ31591.1 - 3.7e-07 30.3 0.0 8.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EEQ31592.1 - 1.4e-29 103.3 0.0 1.5e-28 99.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31592.1 - 2.6e-12 46.6 0.1 1.1e-05 24.8 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ31592.1 - 0.13 11.0 0.0 0.44 9.3 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EEQ31592.1 - 0.2 11.2 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cwf_Cwc_15 PF04889.12 EEQ31594.1 - 2e-87 293.0 14.9 2.3e-87 292.8 14.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 EEQ31594.1 - 0.053 13.4 14.4 0.075 12.9 14.4 1.5 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Casc1_N PF15927.5 EEQ31594.1 - 0.11 12.2 14.8 0.24 11.1 14.8 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF3752 PF12572.8 EEQ31594.1 - 0.19 12.2 17.5 0.26 11.8 17.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) DUF3381 PF11861.8 EEQ31594.1 - 1.1 9.1 14.4 1.7 8.5 14.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PA26 PF04636.13 EEQ31594.1 - 1.3 7.8 3.8 1.5 7.6 3.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GTP-bdg_M PF16360.5 EEQ31594.1 - 1.7 9.3 11.5 2.8e+02 2.2 11.5 3.1 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region APH PF01636.23 EEQ31598.1 - 7.2e-12 45.7 0.0 9.4e-11 42.1 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3246 PF11596.8 EEQ31598.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Med22 PF06179.12 EEQ31599.1 - 1.9e-20 73.0 2.1 2.3e-20 72.8 2.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Alpha-mann_mid PF09261.11 EEQ31599.1 - 0.14 12.3 0.7 0.7 10.1 0.7 2.2 1 1 0 1 1 1 0 Alpha mannosidase middle domain PrmC_N PF17827.1 EEQ31599.1 - 0.4 11.3 2.9 3.5 8.3 2.9 2.1 1 1 0 1 1 1 0 PrmC N-terminal domain DHFR_1 PF00186.19 EEQ31600.1 - 1.8e-17 63.5 0.2 6.4e-12 45.5 0.1 3.7 1 1 1 2 2 2 2 Dihydrofolate reductase Voltage_CLC PF00654.20 EEQ31601.1 - 1.5e-91 307.3 23.8 6.2e-91 305.3 20.2 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel Btz PF09405.10 EEQ31601.1 - 0.22 11.8 1.2 0.38 11.0 1.2 1.2 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Lipase_GDSL_2 PF13472.6 EEQ31603.1 - 1.6e-14 54.7 0.1 1.4e-12 48.4 0.1 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EEQ31603.1 - 1.6e-10 41.3 0.0 8.1e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase Trimer_CC PF08954.11 EEQ31604.1 - 0.064 12.8 0.1 0.26 10.9 0.1 2.0 1 0 0 1 1 1 0 Trimerisation motif Ephrin PF00812.17 EEQ31604.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin APH PF01636.23 EEQ31606.1 - 6e-14 52.5 0.0 9.1e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ31606.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box-like PF12937.7 EEQ31607.1 - 8.1e-05 22.4 0.2 8.1e-05 22.4 0.2 2.3 3 0 0 3 3 3 1 F-box-like Isochorismatase PF00857.20 EEQ31611.1 - 6.8e-26 91.5 0.0 8.2e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family HK PF02110.15 EEQ31612.1 - 3.6e-71 239.4 0.4 9.7e-69 231.5 0.4 2.6 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EEQ31612.1 - 4.2e-59 198.9 3.9 6.7e-59 198.3 3.9 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase ADH_zinc_N PF00107.26 EEQ31612.1 - 0.0016 18.4 0.6 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase QRPTase_C PF01729.19 EEQ31612.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain NMO PF03060.15 EEQ31612.1 - 0.12 11.8 8.0 0.24 10.7 7.3 1.8 1 1 0 1 1 1 0 Nitronate monooxygenase eIF-5_eIF-2B PF01873.17 EEQ31613.1 - 4.7e-39 132.9 0.0 8.3e-39 132.1 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EEQ31613.1 - 3.2e-21 75.3 0.2 3.2e-21 75.3 0.2 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Pns11_12 PF17464.2 EEQ31613.1 - 1 9.0 7.2 0.67 9.6 4.8 1.8 2 0 0 2 2 2 0 Non-structural protein 11 and 12 Dicer_dimer PF03368.14 EEQ31614.1 - 0.042 14.0 0.0 0.19 11.9 0.0 2.2 1 0 0 1 1 1 0 Dicer dimerisation domain TTRAP PF14203.6 EEQ31614.1 - 0.17 11.9 0.1 2.3 8.3 0.0 3.0 4 0 0 4 4 4 0 Putative tranposon-transfer assisting protein PT PF04886.12 EEQ31615.1 - 6.5 6.4 20.8 0.053 13.1 5.9 3.7 3 1 0 3 3 3 0 PT repeat DNA_ligase_A_M PF01068.21 EEQ31616.1 - 1.3e-60 204.5 0.4 2e-58 197.4 0.4 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EEQ31616.1 - 5.7e-43 147.2 0.1 1.5e-42 145.9 0.1 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EEQ31616.1 - 1.1e-27 96.5 0.0 4.5e-27 94.6 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EEQ31616.1 - 5.8e-06 26.7 0.1 9.6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 RNA ligase DUF4821 PF16092.5 EEQ31616.1 - 0.00038 20.2 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4821) Synaptonemal_3 PF15191.6 EEQ31616.1 - 0.039 13.7 0.0 0.23 11.3 0.0 2.3 2 1 0 2 2 2 0 Synaptonemal complex central element protein 3 mRNA_cap_enzyme PF01331.19 EEQ31617.1 - 4.2e-52 176.8 0.5 6e-52 176.3 0.5 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EEQ31617.1 - 1.7e-35 121.9 0.0 3.5e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EEQ31617.1 - 1.3e-08 34.7 0.8 8.3e-07 28.8 0.3 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain SCA7 PF08313.12 EEQ31618.1 - 5.8e-31 106.2 0.8 5.8e-31 106.2 0.8 2.7 3 0 0 3 3 3 1 SCA7, zinc-binding domain DUF2151 PF10221.9 EEQ31618.1 - 0.064 11.8 7.9 0.097 11.2 7.9 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Neugrin PF06413.11 EEQ31618.1 - 0.52 10.3 9.7 0.95 9.4 9.7 1.4 1 0 0 1 1 1 0 Neugrin ATP-synt_Eps PF04627.13 EEQ31618.1 - 1.4 9.0 5.9 3.3 7.8 5.9 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain CDC45 PF02724.14 EEQ31618.1 - 2.5 6.3 8.4 3.6 5.8 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EEQ31618.1 - 2.9 6.8 6.6 5.5 5.9 6.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4551 PF15087.6 EEQ31618.1 - 9.7 4.9 7.8 13 4.5 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) AIRC PF00731.20 EEQ31619.1 - 1e-58 197.1 2.2 1.9e-58 196.3 2.2 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EEQ31619.1 - 1e-50 171.7 0.0 2.2e-50 170.6 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 EEQ31619.1 - 2.7e-18 65.4 0.0 7.4e-18 64.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EEQ31619.1 - 3.7e-06 26.6 0.3 1.4e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PrpR_N PF06506.11 EEQ31619.1 - 0.00047 19.8 0.7 0.0037 16.8 0.1 2.4 2 0 0 2 2 2 1 Propionate catabolism activator AlaDh_PNT_C PF01262.21 EEQ31619.1 - 0.0043 16.4 0.1 0.0087 15.4 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Dala_Dala_lig_C PF07478.13 EEQ31619.1 - 0.0057 16.2 0.0 0.055 13.0 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CoA_binding_2 PF13380.6 EEQ31619.1 - 0.074 13.5 1.2 38 4.8 0.0 3.4 2 1 1 3 3 3 0 CoA binding domain 2-Hacid_dh_C PF02826.19 EEQ31619.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_2 PF12796.7 EEQ31620.1 - 2.4e-43 146.6 8.3 5.5e-12 46.1 0.1 6.4 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ31620.1 - 1.2e-37 127.8 6.6 5.2e-12 46.0 0.2 7.0 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ31620.1 - 1.1e-36 124.4 14.4 4.4e-11 42.8 0.1 6.6 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EEQ31620.1 - 7.4e-35 117.9 15.6 1.2e-06 28.6 0.0 9.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 EEQ31620.1 - 1.1e-29 99.1 8.8 2.2e-05 24.5 0.1 9.2 10 0 0 10 10 10 5 Ankyrin repeat Hexapep PF00132.24 EEQ31621.1 - 7.7e-14 50.8 8.2 1.2e-10 40.7 4.6 3.2 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EEQ31621.1 - 1.3e-13 51.0 0.2 2e-13 50.3 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EEQ31621.1 - 1e-10 41.2 8.8 1e-09 38.0 3.7 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase RNase_P_pop3 PF08228.11 EEQ31622.1 - 0.0027 17.8 0.0 0.0059 16.7 0.0 1.6 1 1 0 1 1 1 1 RNase P subunit Pop3 ketoacyl-synt PF00109.26 EEQ31623.1 - 1.9e-73 247.1 0.0 3.5e-73 246.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EEQ31623.1 - 1.5e-43 149.3 0.0 1.3e-42 146.2 0.0 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EEQ31623.1 - 1.6e-35 123.2 0.0 3.1e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ31623.1 - 1.8e-33 115.1 0.4 1.2e-32 112.4 0.8 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EEQ31623.1 - 9.2e-12 45.2 1.0 2.8e-11 43.6 1.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 EEQ31623.1 - 2.6e-11 43.3 0.1 4.1e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EEQ31623.1 - 3e-06 27.7 0.0 8.4e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EEQ31623.1 - 2.4e-05 23.8 0.0 5.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Raf1_HTH PF18579.1 EEQ31623.1 - 0.054 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain DUF4813 PF16072.5 EEQ31623.1 - 2.4 7.7 8.4 0.39 10.3 3.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) DUF1772 PF08592.11 EEQ31624.1 - 2.2e-11 44.2 0.0 3.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Lactamase_B PF00753.27 EEQ31625.1 - 3.1e-14 53.4 4.0 6.8e-14 52.3 4.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EEQ31625.1 - 0.00037 20.1 0.3 0.00069 19.2 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_2 PF00891.18 EEQ31626.1 - 1.2e-05 24.7 0.2 0.0027 17.0 0.2 2.9 1 1 0 1 1 1 1 O-methyltransferase domain Zn_clus PF00172.18 EEQ31628.1 - 1.2e-08 34.9 10.2 2.7e-08 33.8 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_1 PF00175.21 EEQ31629.1 - 1.6e-21 77.0 0.0 2.3e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEQ31629.1 - 1.6e-15 57.2 0.0 2.6e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EEQ31629.1 - 3.7e-06 27.1 0.0 0.003 17.7 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF1206 PF06724.11 EEQ31629.1 - 0.09 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Epimerase PF01370.21 EEQ31630.1 - 3.1e-14 53.0 0.4 1e-13 51.3 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EEQ31630.1 - 1.9e-11 44.2 1.8 4.4e-11 43.0 0.3 2.0 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EEQ31630.1 - 2.7e-07 29.9 0.0 4.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EEQ31630.1 - 3.4e-06 26.7 0.1 0.00013 21.5 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EEQ31630.1 - 5.6e-06 26.0 0.0 8.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EEQ31630.1 - 7.3e-06 25.7 0.1 1.2e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EEQ31630.1 - 4.2e-05 22.8 0.0 5.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EEQ31630.1 - 0.00027 20.2 0.0 0.0037 16.5 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 EEQ31630.1 - 0.041 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DXP_reductoisom PF02670.16 EEQ31630.1 - 0.15 12.8 0.1 0.25 12.1 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3HCDH_N PF02737.18 EEQ31630.1 - 0.16 11.8 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_2 PF00891.18 EEQ31631.1 - 6.1e-16 58.4 0.0 8.1e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EEQ31631.1 - 0.00028 20.8 0.1 0.00055 19.9 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain DUF4880 PF16220.5 EEQ31631.1 - 0.058 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) DUF3517 PF12030.8 EEQ31633.1 - 9.3e-97 323.9 0.2 1.7e-96 323.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 EEQ31633.1 - 3.4e-37 128.3 0.0 6.9e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ31633.1 - 3.5e-21 76.1 0.0 6.9e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase p47_phox_C PF08944.11 EEQ31633.1 - 0.13 11.7 1.6 0.39 10.2 1.6 1.8 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain MazG PF03819.17 EEQ31633.1 - 0.14 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain ADD_ATRX PF17981.1 EEQ31633.1 - 0.15 11.9 0.1 0.5 10.3 0.1 1.8 1 0 0 1 1 1 0 Cysteine Rich ADD domain 2-oxoacid_dh PF00198.23 EEQ31633.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) TrkH PF02386.16 EEQ31634.1 - 3.9e-121 405.0 10.1 6.8e-119 397.6 3.8 3.1 2 1 0 2 2 2 2 Cation transport protein GTA_holin_3TM PF11351.8 EEQ31634.1 - 0.79 10.3 3.3 6.3 7.4 0.2 3.3 3 1 0 3 3 3 0 Holin of 3TMs, for gene-transfer release TFIIE_alpha PF02002.17 EEQ31635.1 - 5.1e-19 68.1 0.0 9.3e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_Crp_2 PF13545.6 EEQ31635.1 - 0.0067 16.4 0.6 0.012 15.6 0.6 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain zf-FPG_IleRS PF06827.14 EEQ31635.1 - 0.24 11.3 0.8 28 4.7 0.2 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS PseudoU_synth_1 PF01416.20 EEQ31636.1 - 4.1e-10 40.1 0.0 7.6e-08 32.8 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase ATP_bind_2 PF03668.15 EEQ31636.1 - 0.085 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family Host_attach PF10116.9 EEQ31636.1 - 0.1 13.2 2.8 0.39 11.3 2.8 2.0 1 0 0 1 1 1 0 Protein required for attachment to host cells DUF2229 PF09989.9 EEQ31636.1 - 0.8 9.3 4.2 3.1 7.4 0.0 3.0 3 0 0 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) Anillin PF08174.11 EEQ31637.1 - 3.5e-09 37.2 0.6 1e-08 35.7 0.0 2.2 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.29 EEQ31637.1 - 3.7e-08 33.8 0.0 1.3e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 PH domain DEAD PF00270.29 EEQ31638.1 - 2.2e-31 109.0 0.0 4e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ31638.1 - 2e-21 76.4 0.1 1e-17 64.5 0.1 2.8 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ31638.1 - 2.1e-05 24.6 0.0 0.00042 20.4 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EEQ31638.1 - 0.034 12.9 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain SET PF00856.28 EEQ31641.1 - 5.3e-10 39.9 0.0 1.1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 SET domain APH PF01636.23 EEQ31642.1 - 5.5e-08 33.0 0.0 9.8e-07 28.9 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ31642.1 - 0.069 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L14 PF00238.19 EEQ31643.1 - 1.1e-47 161.2 1.6 1.2e-47 161.0 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_POL_M_15KD PF02150.16 EEQ31644.1 - 3.4e-12 46.0 1.0 3.4e-12 46.0 1.0 2.8 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 EEQ31644.1 - 0.077 13.3 5.6 0.31 11.4 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme FYVE PF01363.21 EEQ31644.1 - 0.36 11.0 8.1 2.3 8.4 1.1 2.3 2 0 0 2 2 2 0 FYVE zinc finger Rotamase PF00639.21 EEQ31646.1 - 2.1e-22 79.9 0.1 3.1e-22 79.4 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EEQ31646.1 - 6.1e-15 55.8 0.0 9.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EEQ31646.1 - 0.00014 22.6 0.0 0.0002 22.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain RRM_1 PF00076.22 EEQ31649.1 - 1.7e-15 56.6 0.0 2.7e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb4 PF03874.16 EEQ31649.1 - 0.14 12.5 0.1 0.2 12.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 SNO PF01174.19 EEQ31650.1 - 1.4e-53 181.5 0.0 4.8e-43 147.2 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EEQ31650.1 - 2.8e-09 36.9 0.0 2.3e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EEQ31650.1 - 0.00045 20.1 0.0 0.0045 16.8 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 EEQ31650.1 - 0.0024 17.5 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EEQ31650.1 - 0.0046 16.8 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ACPS PF01648.20 EEQ31652.1 - 4.1e-13 49.5 0.0 1.4e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.21 EEQ31653.1 - 2.3e-30 104.9 0.0 4.1e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TPR_1 PF00515.28 EEQ31654.1 - 2.2e-42 141.2 6.3 1.2e-08 34.4 0.0 7.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ31654.1 - 5e-37 123.0 12.8 5.4e-06 26.1 0.0 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ31654.1 - 1.3e-32 111.8 16.1 1.5e-24 86.0 0.2 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EEQ31654.1 - 7.2e-32 108.8 1.5 7.5e-09 35.1 0.5 8.2 6 1 2 8 8 8 7 TPR repeat TPR_8 PF13181.6 EEQ31654.1 - 1.1e-27 93.8 10.0 0.00013 21.9 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ31654.1 - 1.8e-24 86.0 11.6 8.5e-08 32.6 0.7 7.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ31654.1 - 5e-21 73.6 4.0 0.047 14.5 0.0 9.2 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ31654.1 - 2.4e-18 66.5 7.9 1.1e-06 29.1 0.1 7.9 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ31654.1 - 3.4e-17 62.5 16.7 0.0027 18.0 0.6 7.9 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ31654.1 - 4.5e-15 54.9 11.8 0.032 14.6 0.0 9.7 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ31654.1 - 5.7e-13 47.9 2.0 0.0037 17.2 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ31654.1 - 1.2e-08 35.0 5.1 3.4 8.5 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ31654.1 - 3.5e-08 33.5 0.3 0.0079 16.3 0.0 4.8 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EEQ31654.1 - 2.9e-05 23.5 2.6 0.61 9.3 0.8 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ31654.1 - 0.00042 20.1 4.1 2.5 8.1 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat ChAPs PF09295.10 EEQ31654.1 - 0.00066 18.8 0.1 0.18 10.8 0.0 2.6 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 EEQ31654.1 - 0.049 13.0 4.7 1.7 7.9 0.0 4.0 4 1 1 5 5 5 0 MalT-like TPR region PPTA PF01239.22 EEQ31654.1 - 0.059 13.1 0.3 0.17 11.7 0.3 1.9 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat DUF3741 PF12552.8 EEQ31654.1 - 0.15 12.0 0.0 0.54 10.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) NARP1 PF12569.8 EEQ31654.1 - 0.28 10.1 3.7 0.77 8.6 0.1 3.1 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 MIT PF04212.18 EEQ31654.1 - 0.41 10.7 4.8 12 6.1 0.6 4.6 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 EEQ31654.1 - 0.44 10.2 5.7 4.8 6.8 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 EEQ31654.1 - 1.7 8.3 5.9 22 4.7 0.4 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TMEM208_SND2 PF05620.11 EEQ31655.1 - 5.8e-55 185.6 0.0 6.5e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF1441 PF07278.11 EEQ31656.1 - 0.027 14.4 0.1 0.81 9.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1441) YtxH PF12732.7 EEQ31656.1 - 0.057 13.9 4.6 2.1 9.0 1.0 4.2 3 1 0 3 3 3 0 YtxH-like protein ABC_tran PF00005.27 EEQ31657.1 - 1.1e-41 142.6 0.0 2.3e-20 73.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ31657.1 - 8.7e-25 87.9 24.9 1.1e-23 84.2 11.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EEQ31657.1 - 5e-10 39.2 3.2 0.0049 16.3 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEQ31657.1 - 1e-08 35.3 5.7 0.1 12.4 0.1 4.4 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ31657.1 - 2.6e-07 30.3 0.1 0.029 14.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ31657.1 - 8.8e-07 29.3 0.0 0.033 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEQ31657.1 - 1.6e-05 25.4 0.1 0.064 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EEQ31657.1 - 5e-05 23.3 0.4 0.35 11.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ31657.1 - 7.5e-05 22.7 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EEQ31657.1 - 8.1e-05 23.2 0.1 0.16 12.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 EEQ31657.1 - 0.0001 22.5 1.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 EEQ31657.1 - 0.00017 22.2 0.3 0.81 10.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EEQ31657.1 - 0.00034 20.8 0.0 0.11 12.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EEQ31657.1 - 0.00054 19.1 0.0 0.087 11.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 EEQ31657.1 - 0.00074 19.9 0.0 0.66 10.4 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EEQ31657.1 - 0.00075 19.6 0.3 0.34 10.9 0.1 2.4 2 0 0 2 2 2 1 Dynamin family AAA_7 PF12775.7 EEQ31657.1 - 0.00079 19.0 0.0 0.62 9.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Adeno_IVa2 PF02456.15 EEQ31657.1 - 0.0016 17.3 0.1 0.3 9.8 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_15 PF13175.6 EEQ31657.1 - 0.0016 18.2 0.0 0.81 9.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 EEQ31657.1 - 0.0034 17.6 0.9 10 6.5 0.2 3.9 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 EEQ31657.1 - 0.0082 15.7 0.2 0.55 9.8 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EEQ31657.1 - 0.0098 15.7 0.1 0.17 11.7 0.2 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 EEQ31657.1 - 0.011 15.2 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EEQ31657.1 - 0.026 13.8 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 EEQ31657.1 - 0.028 14.2 0.7 21 4.8 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EEQ31657.1 - 0.031 14.7 0.0 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 EEQ31657.1 - 0.036 13.5 0.2 9.6 5.5 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ31657.1 - 0.06 13.3 0.7 18 5.3 0.0 3.4 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EEQ31657.1 - 0.074 12.6 0.0 4.6 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 EEQ31657.1 - 0.1 11.5 0.0 6.6 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.9 EEQ31657.1 - 0.12 12.1 0.6 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EEQ31657.1 - 0.13 12.2 0.1 14 5.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 EEQ31657.1 - 0.15 11.2 0.0 23 4.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 EEQ31657.1 - 0.18 11.5 0.0 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EEQ31657.1 - 0.22 11.3 1.1 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PBP PF01161.20 EEQ31658.1 - 0.046 14.0 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein RINGv PF12906.7 EEQ31659.1 - 5.6e-16 58.4 10.6 9.6e-16 57.7 10.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EEQ31659.1 - 0.0042 17.4 9.0 0.0075 16.6 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EEQ31659.1 - 0.52 10.4 3.3 1.1 9.3 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EEQ31659.1 - 0.81 9.5 6.5 1.4 8.8 6.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zf_RING PF16744.5 EEQ31659.1 - 1.7 8.8 4.4 3.4 7.9 4.4 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_3 PF13920.6 EEQ31659.1 - 4.6 7.2 6.1 9.2 6.2 6.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EEQ31659.1 - 6.2 7.1 6.9 13 6.0 6.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain DnaJ_CXXCXGXG PF00684.19 EEQ31659.1 - 9.5 6.7 6.4 22 5.5 6.4 1.5 1 1 0 1 1 1 0 DnaJ central domain HeLo PF14479.6 EEQ31660.1 - 0.0004 20.3 0.2 0.0076 16.1 0.2 2.3 1 1 0 1 1 1 1 Prion-inhibition and propagation ACC_central PF08326.12 EEQ31661.1 - 7.2e-283 940.3 0.0 8.9e-283 940.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EEQ31661.1 - 1.4e-174 581.4 0.0 8.7e-173 575.5 0.0 2.5 2 1 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EEQ31661.1 - 2.9e-54 183.8 0.0 5.6e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EEQ31661.1 - 1.4e-28 99.6 0.1 2.8e-28 98.6 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EEQ31661.1 - 2.4e-23 82.3 0.0 9.7e-20 70.7 0.0 3.3 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EEQ31661.1 - 2.4e-16 59.3 0.2 7.5e-16 57.7 0.1 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EEQ31661.1 - 5.8e-05 22.7 0.0 0.00014 21.4 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EEQ31661.1 - 0.00025 21.1 0.0 0.00067 19.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EEQ31661.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Antiterm PF03589.13 EEQ31661.1 - 0.054 13.8 0.0 0.82 10.0 0.0 2.8 2 0 0 2 2 2 0 Antitermination protein DUF737 PF05300.11 EEQ31661.1 - 0.058 13.7 0.3 0.17 12.2 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF737) ATPgrasp_Ter PF15632.6 EEQ31661.1 - 0.094 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon NUDE_C PF04880.13 EEQ31662.1 - 3.1e-56 190.7 11.0 3.1e-56 190.7 11.0 4.8 3 1 1 4 4 4 1 NUDE protein, C-terminal conserved region DMPK_coil PF08826.10 EEQ31662.1 - 0.013 15.6 1.2 0.013 15.6 1.2 4.4 2 1 3 5 5 5 0 DMPK coiled coil domain like ADIP PF11559.8 EEQ31662.1 - 0.15 12.2 23.3 1.2 9.3 5.5 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 EEQ31662.1 - 0.59 10.6 32.1 0.047 14.1 8.7 4.2 2 1 2 4 4 4 0 Cell division protein ZapB Baculo_PEP_C PF04513.12 EEQ31662.1 - 0.99 9.4 3.6 0.33 11.0 0.6 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Gp-FAR-1 PF05823.12 EEQ31662.1 - 1.6 9.1 6.8 0.14 12.5 1.2 2.1 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Lectin_N PF03954.14 EEQ31662.1 - 1.8 8.3 8.6 0.47 10.2 2.1 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Fez1 PF06818.15 EEQ31662.1 - 3.3 8.1 25.1 0.9 10.0 12.9 3.0 2 1 1 3 3 3 0 Fez1 DUF16 PF01519.16 EEQ31662.1 - 7.1 7.2 15.6 0.35 11.4 5.2 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Hexokinase_1 PF00349.21 EEQ31663.1 - 1.2e-49 168.9 0.0 1.7e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EEQ31663.1 - 2.4e-45 154.9 0.0 3.2e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Isochorismatase PF00857.20 EEQ31664.1 - 1.4e-37 129.6 0.0 7.6e-37 127.2 0.0 1.9 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.15 EEQ31664.1 - 8e-06 26.5 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 EEQ31664.1 - 0.057 13.8 0.0 0.094 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.13 EEQ31665.1 - 2.5e-40 137.6 0.0 3.1e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EEQ31665.1 - 0.006 16.5 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family Herpes_capsid PF06112.11 EEQ31665.1 - 0.014 15.4 3.5 0.018 15.1 3.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein NLBH PF05211.12 EEQ31665.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) DUF2040 PF09745.9 EEQ31666.1 - 3.1e-38 130.5 16.0 3.1e-38 130.5 16.0 3.7 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Zip PF02535.22 EEQ31667.1 - 1.8e-25 89.9 2.1 2.9e-25 89.2 2.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Endonuclease_NS PF01223.23 EEQ31668.1 - 7.7e-65 218.9 0.0 9.8e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease BTB PF00651.31 EEQ31669.1 - 0.043 14.0 0.3 0.85 9.9 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain Sec7 PF01369.20 EEQ31670.1 - 6.6e-30 104.2 0.1 1.1e-29 103.5 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EEQ31670.1 - 3.3e-07 30.7 0.1 8.8e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EEQ31670.1 - 1e-05 26.0 0.0 3.3e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 PH domain SET PF00856.28 EEQ31671.1 - 0.0037 17.7 0.0 0.28 11.5 0.0 2.4 1 1 2 3 3 3 3 SET domain zf-RING_UBOX PF13445.6 EEQ31672.1 - 4e-06 26.7 7.7 1.3e-05 25.1 1.0 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EEQ31672.1 - 1.7e-05 25.1 8.1 0.00049 20.4 0.8 3.1 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ31672.1 - 2.7e-05 23.9 9.2 7.4e-05 22.5 1.4 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 EEQ31672.1 - 8.1e-05 22.7 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 EEQ31672.1 - 0.00011 22.0 4.0 0.00011 22.0 4.0 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EEQ31672.1 - 0.0012 18.7 12.9 0.0014 18.4 1.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EEQ31672.1 - 0.0013 18.2 1.8 0.0013 18.2 1.8 3.3 2 1 1 3 3 2 2 Rtf2 RING-finger FYVE PF01363.21 EEQ31672.1 - 0.0015 18.6 11.8 0.0062 16.6 4.4 3.5 2 2 1 3 3 3 1 FYVE zinc finger zf-C3HC4_5 PF17121.5 EEQ31672.1 - 0.0022 17.8 0.5 0.0059 16.5 0.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ31672.1 - 0.0027 17.5 8.7 0.0033 17.3 1.2 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF1195 PF06708.11 EEQ31672.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Prok-RING_4 PF14447.6 EEQ31672.1 - 0.02 14.7 5.4 0.02 14.7 5.4 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EEQ31672.1 - 1.2 9.4 12.8 1.1 9.5 5.8 3.5 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING IBR PF01485.21 EEQ31672.1 - 1.6 9.0 12.2 1.3 9.3 1.8 3.4 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain CDC45 PF02724.14 EEQ31672.1 - 3.2 5.9 10.0 4.3 5.5 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Zn_ribbon_17 PF17120.5 EEQ31672.1 - 5.4 6.7 9.6 4.2 7.1 0.6 2.6 3 0 0 3 3 2 0 Zinc-ribbon, C4HC2 type SET PF00856.28 EEQ31673.1 - 4.1e-15 56.6 0.2 5.6e-14 52.9 0.2 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 EEQ31673.1 - 0.057 14.1 0.0 7 7.4 0.0 2.3 2 0 0 2 2 2 0 SAF domain Peptidase_M14 PF00246.24 EEQ31674.1 - 2.5e-73 247.4 0.0 3.3e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase NicO PF03824.16 EEQ31675.1 - 3e-45 154.8 15.9 3e-42 144.9 1.8 2.5 3 0 0 3 3 3 2 High-affinity nickel-transport protein Peptidase_S8 PF00082.22 EEQ31676.1 - 3.7e-35 121.6 16.1 7.1e-35 120.7 16.2 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ31676.1 - 1.1e-17 64.4 0.0 2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DNA_pol_B_thumb PF14791.6 EEQ31677.1 - 1e-22 80.0 0.6 1.3e-21 76.5 0.1 2.7 3 0 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EEQ31677.1 - 3.9e-18 65.0 0.8 7.7e-18 64.1 0.8 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 EEQ31677.1 - 3.7e-17 62.6 0.0 1.1e-15 57.8 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.6 EEQ31677.1 - 2.6e-07 30.9 0.0 7.2e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain CENP-K PF11802.8 EEQ31677.1 - 0.033 13.8 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Centromere-associated protein K BRCT_2 PF16589.5 EEQ31677.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 EEQ31677.1 - 0.062 13.9 0.0 0.18 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain PhoLip_ATPase_C PF16212.5 EEQ31678.1 - 8.7e-83 277.9 17.2 8.7e-83 277.9 17.2 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEQ31678.1 - 9.6e-27 92.5 7.9 3.4e-26 90.7 7.9 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EEQ31678.1 - 2.1e-13 50.2 0.0 1.3e-12 47.6 0.0 2.3 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEQ31678.1 - 3.2e-11 43.9 1.1 1.9e-06 28.3 0.2 3.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEQ31678.1 - 2e-07 30.7 0.0 5.8e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EEQ31678.1 - 0.0028 17.4 0.4 0.022 14.5 0.1 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNase_PH PF01138.21 EEQ31679.1 - 6.4e-19 68.8 0.0 1.2e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EEQ31679.1 - 7.8e-07 29.0 0.0 2e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 WD40 PF00400.32 EEQ31680.1 - 6e-32 109.2 30.2 3.7e-07 30.7 1.9 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ31680.1 - 3.3e-18 65.8 0.1 0.00014 22.1 0.0 5.1 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EEQ31680.1 - 0.036 12.4 0.0 0.11 10.7 0.0 1.7 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz HTH_32 PF13565.6 EEQ31681.1 - 7.1e-08 33.0 0.1 2.5e-07 31.2 0.0 1.8 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 EEQ31681.1 - 1.7e-07 31.4 0.6 6.2e-07 29.6 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EEQ31681.1 - 1.2e-06 28.1 0.2 0.002 17.8 0.0 2.2 2 0 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 EEQ31681.1 - 4e-05 23.3 0.4 0.013 15.2 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_24 PF13412.6 EEQ31681.1 - 0.00014 21.3 0.8 0.63 9.6 0.1 2.9 2 1 0 2 2 2 2 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 EEQ31681.1 - 0.00022 20.9 0.3 0.022 14.5 0.0 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_29 PF13551.6 EEQ31681.1 - 0.0003 20.7 0.2 0.058 13.4 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_WhiA PF02650.14 EEQ31681.1 - 0.0005 20.3 0.2 0.0039 17.5 0.1 2.1 2 0 0 2 2 2 1 WhiA C-terminal HTH domain CENP-B_N PF04218.13 EEQ31681.1 - 0.0017 17.9 0.2 0.1 12.3 0.1 2.2 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_11 PF08279.12 EEQ31681.1 - 0.0056 16.6 0.4 4.1 7.4 0.1 2.4 2 1 0 2 2 2 2 HTH domain TrmB PF01978.19 EEQ31681.1 - 0.0082 16.0 0.2 2.9 7.8 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB TnsD PF15978.5 EEQ31681.1 - 0.0084 15.1 0.1 0.011 14.7 0.1 1.3 1 1 0 1 1 1 1 Tn7-like transposition protein D HTH_36 PF13730.6 EEQ31681.1 - 0.0086 16.0 0.1 4 7.5 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_7 PF02796.15 EEQ31681.1 - 0.02 14.9 3.2 0.37 10.9 1.4 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_20 PF12840.7 EEQ31681.1 - 0.028 14.5 0.0 5.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 EEQ31681.1 - 0.081 13.1 0.1 8 6.7 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 EEQ31681.1 - 0.11 12.0 0.2 0.55 9.8 0.0 2.0 2 1 0 2 2 2 0 Sigma-70, region 4 Fe_dep_repress PF01325.19 EEQ31681.1 - 0.12 12.6 0.1 1.9 8.8 0.1 2.2 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain MBOAT PF03062.19 EEQ31683.1 - 1.4e-24 87.1 16.3 2.3e-24 86.4 16.3 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EEQ31683.1 - 0.0039 17.4 2.6 0.011 16.0 2.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF2530 PF10745.9 EEQ31683.1 - 1 9.7 8.5 1.9 8.8 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) MAPEG PF01124.18 EEQ31684.1 - 1.7e-23 83.0 4.0 2e-23 82.7 4.0 1.0 1 0 0 1 1 1 1 MAPEG family OMPdecase PF00215.24 EEQ31685.1 - 3.7e-74 249.1 0.1 4.2e-74 248.9 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pkinase_fungal PF17667.1 EEQ31686.1 - 8.9e-126 419.9 0.0 1.1e-125 419.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EEQ31686.1 - 0.0013 18.2 0.0 0.0053 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain OTT_1508_deam PF14441.6 EEQ31687.1 - 1.4e-19 69.8 0.3 3.3e-19 68.6 0.3 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase AA_permease_2 PF13520.6 EEQ31688.1 - 1.9e-45 155.5 47.3 2.5e-45 155.1 47.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ31688.1 - 2.2e-17 62.8 43.7 2.1e-16 59.6 43.7 2.2 1 1 0 1 1 1 1 Amino acid permease YlaH PF14036.6 EEQ31688.1 - 0.0018 18.6 1.6 0.0018 18.6 1.6 3.9 4 0 0 4 4 4 1 YlaH-like protein ER_lumen_recept PF00810.18 EEQ31688.1 - 0.035 14.9 0.9 0.035 14.9 0.9 2.9 2 1 0 2 2 2 0 ER lumen protein retaining receptor Pox_A14 PF05767.12 EEQ31688.1 - 0.042 14.0 0.4 0.042 14.0 0.4 3.5 3 2 2 5 5 5 0 Poxvirus virion envelope protein A14 APH PF01636.23 EEQ31689.1 - 2.5e-09 37.4 0.2 8.6e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EEQ31689.1 - 0.0027 17.1 0.1 0.02 14.2 0.1 2.0 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.20 EEQ31689.1 - 0.012 15.2 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EEQ31689.1 - 0.023 13.6 0.1 0.087 11.7 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1679) DUF3368 PF11848.8 EEQ31690.1 - 0.13 12.0 0.0 6.8 6.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) Aminotran_1_2 PF00155.21 EEQ31691.1 - 1.6e-69 234.8 0.0 1.9e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4246 PF14033.6 EEQ31692.1 - 3.6e-181 603.2 0.0 4.2e-181 603.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EEQ31692.1 - 0.0052 17.2 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DJ-1_PfpI PF01965.24 EEQ31693.1 - 8.6e-22 77.7 0.0 1.1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family IMS PF00817.20 EEQ31694.1 - 5.3e-39 133.6 0.0 1e-38 132.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EEQ31694.1 - 1.4e-23 83.1 0.0 3.6e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EEQ31694.1 - 1.7e-14 54.5 0.0 3.8e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 EEQ31694.1 - 2.3e-13 49.1 12.6 1.4e-08 33.9 2.1 4.1 3 0 0 3 3 3 2 Ubiquitin binding region BRCT_2 PF16589.5 EEQ31694.1 - 5.9e-09 36.2 0.0 2.3e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EEQ31694.1 - 2.6e-05 24.4 0.0 6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 EEQ31694.1 - 3.8e-05 24.0 0.0 0.00018 21.8 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 EEQ31694.1 - 0.00055 20.3 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 minimal CRISPR polymerase domain IMS_HHH PF11798.8 EEQ31694.1 - 0.0033 17.6 0.3 0.014 15.7 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 EEQ31694.1 - 0.033 14.1 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain CSTF_C PF14304.6 EEQ31694.1 - 2.9 7.5 5.2 9.5 5.9 0.0 3.3 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal NPL PF17800.1 EEQ31695.1 - 2.5e-31 108.4 1.2 2.5e-31 108.4 1.2 2.6 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 EEQ31695.1 - 6e-31 106.6 0.1 2.5e-30 104.7 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SDA1 PF05285.12 EEQ31695.1 - 5.9 6.2 49.1 0.37 10.2 23.1 2.2 2 0 0 2 2 2 0 SDA1 Pkinase PF00069.25 EEQ31696.1 - 1.7e-48 165.3 0.8 4.5e-26 91.8 0.1 3.4 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31696.1 - 1.3e-19 70.5 0.0 5.9e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EEQ31696.1 - 0.012 15.5 0.1 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EEQ31696.1 - 0.031 13.2 0.6 0.056 12.4 0.6 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF3591 PF12157.8 EEQ31697.1 - 2.5e-165 550.4 5.0 4.2e-87 292.7 0.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 EEQ31697.1 - 0.0049 16.9 0.7 0.0087 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EEQ31697.1 - 0.0066 16.3 1.2 0.016 15.1 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Methyltransf_15 PF09445.10 EEQ31698.1 - 8.9e-50 168.5 0.0 1.2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EEQ31698.1 - 5.4e-10 39.4 0.0 6.9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EEQ31698.1 - 1.9e-07 30.9 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EEQ31698.1 - 2.5e-06 27.3 0.0 3.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 EEQ31698.1 - 0.0005 20.0 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EEQ31698.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 EEQ31698.1 - 0.004 17.0 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ31698.1 - 0.0052 17.5 0.0 0.0098 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EEQ31698.1 - 0.028 13.6 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.13 EEQ31698.1 - 0.047 13.1 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.17 EEQ31698.1 - 0.074 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_11 PF08241.12 EEQ31698.1 - 0.078 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EEQ31698.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GRASP55_65 PF04495.14 EEQ31699.1 - 7.2e-42 143.0 0.0 8.4e-40 136.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EEQ31699.1 - 0.13 12.2 0.0 22 5.0 0.0 2.4 2 0 0 2 2 2 0 PDZ domain ApoO PF09769.9 EEQ31700.1 - 4e-42 143.3 0.1 9.7e-42 142.0 0.1 1.6 2 0 0 2 2 2 1 Apolipoprotein O Peptidase_M3 PF01432.20 EEQ31701.1 - 2.8e-121 406.0 0.0 4e-121 405.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 EEQ31701.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Effector protein Methyltransf_23 PF13489.6 EEQ31702.1 - 3.2e-26 92.1 0.0 4.7e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ31702.1 - 6.3e-05 22.8 0.0 0.0009 19.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ31702.1 - 0.0016 19.1 0.0 0.0054 17.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ31702.1 - 0.015 16.0 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HAT PF02184.16 EEQ31702.1 - 0.021 14.8 2.0 6.3 6.9 0.0 3.5 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat Methyltransf_12 PF08242.12 EEQ31702.1 - 0.046 14.5 0.0 0.21 12.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Proteasome PF00227.26 EEQ31705.1 - 3.2e-47 160.5 0.1 4e-47 160.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EEQ31705.1 - 1.2e-14 53.4 0.0 1.2e-14 53.4 0.0 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NUP214 PF16755.5 EEQ31706.1 - 9.4e-12 44.8 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 EEQ31706.1 - 3.5e-06 27.2 0.0 0.00076 19.7 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Syntaxin-6_N PF09177.11 EEQ31706.1 - 0.0084 16.6 1.6 0.01 16.4 0.1 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal WD40 PF00400.32 EEQ31706.1 - 0.075 13.9 0.6 14 6.8 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat HMG_CoA_synt_N PF01154.17 EEQ31707.1 - 9.2e-73 243.8 0.0 1.4e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EEQ31707.1 - 2.2e-64 217.8 0.0 1.4e-63 215.1 0.0 1.9 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Fungal_trans PF04082.18 EEQ31708.1 - 3.7e-13 49.1 0.1 7.6e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ31708.1 - 1.8e-07 31.1 9.4 3.3e-07 30.3 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Orthopox_F8 PF05886.11 EEQ31708.1 - 0.099 12.8 3.7 0.27 11.4 3.7 1.7 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Acetyltransf_1 PF00583.25 EEQ31710.1 - 1.5e-07 31.7 0.0 1.9e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ31710.1 - 1.8e-07 31.4 0.0 2.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ31710.1 - 1.8e-06 27.9 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEQ31710.1 - 2.7e-05 24.3 0.0 0.00028 21.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ31710.1 - 0.0036 17.2 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein MOZ_SAS PF01853.18 EEQ31710.1 - 0.022 14.4 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 MOZ/SAS family Tropomodulin PF03250.14 EEQ31712.1 - 0.053 13.6 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Tropomodulin ADH_N PF08240.12 EEQ31713.1 - 0.0049 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AA_permease_2 PF13520.6 EEQ31715.1 - 7.3e-55 186.5 39.1 9.1e-55 186.2 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ31715.1 - 3.2e-28 98.6 31.6 4.3e-28 98.1 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease Trp_oprn_chp PF09534.10 EEQ31715.1 - 0.089 12.6 0.8 0.2 11.4 0.8 1.6 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1072 PF06380.11 EEQ31715.1 - 2 8.3 5.6 6.4 6.7 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) KH_1 PF00013.29 EEQ31718.1 - 2.3e-39 133.0 2.8 9.9e-18 63.7 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EEQ31718.1 - 1.5e-11 43.9 1.8 0.011 15.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EEQ31718.1 - 9.4e-06 25.4 0.3 0.76 9.7 0.1 3.5 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 EEQ31718.1 - 0.00012 22.0 0.0 0.019 15.0 0.0 2.4 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_5 PF13184.6 EEQ31718.1 - 0.00016 21.7 7.0 0.21 11.7 0.2 3.3 3 0 0 3 3 3 3 NusA-like KH domain CENP-K PF11802.8 EEQ31719.1 - 8.4e-05 22.3 8.9 0.044 13.4 6.9 2.5 2 1 0 2 2 2 2 Centromere-associated protein K Muted PF14942.6 EEQ31719.1 - 0.011 16.1 5.5 0.011 16.1 5.5 2.6 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Fib_alpha PF08702.10 EEQ31719.1 - 0.063 13.5 5.8 0.21 11.7 0.2 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FliD_C PF07195.12 EEQ31719.1 - 0.22 10.9 4.8 0.48 9.8 0.1 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF773 PF05600.12 EEQ31719.1 - 0.7 8.6 9.7 0.15 10.7 5.6 1.9 1 1 1 2 2 2 0 CDK5 regulatory subunit-associated protein 3 YabA PF06156.13 EEQ31719.1 - 1.1 10.0 6.8 8.8 7.0 1.0 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Mod_r PF07200.13 EEQ31719.1 - 2 8.5 12.0 0.46 10.6 2.0 2.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Abhydrolase_1 PF00561.20 EEQ31720.1 - 1.5e-13 51.0 0.0 2.6e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ31720.1 - 4.4e-08 32.7 0.0 9e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ31720.1 - 0.0002 22.0 0.0 0.00063 20.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EEQ31720.1 - 0.002 17.7 0.0 0.013 15.0 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EEQ31720.1 - 0.0058 16.3 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Peptidase_S15 PF02129.18 EEQ31720.1 - 0.12 11.9 0.0 0.61 9.6 0.0 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MFS_1 PF07690.16 EEQ31723.1 - 1.1e-36 126.6 54.2 1.5e-23 83.3 18.9 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ31723.1 - 1.4e-07 30.8 15.9 1.4e-07 30.8 15.9 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter p450 PF00067.22 EEQ31724.1 - 1e-61 209.1 0.0 1.3e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.21 EEQ31725.1 - 5.4e-26 91.4 0.0 1.1e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FSH1 PF03959.13 EEQ31725.1 - 1.2e-21 77.4 0.0 1.2e-20 74.2 0.0 2.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) FAD_binding_6 PF00970.24 EEQ31725.1 - 2.4e-19 69.5 0.0 5.1e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EEQ31725.1 - 9e-13 48.2 0.0 1.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EEQ31725.1 - 3.3e-06 27.3 0.0 0.0013 18.9 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Esterase PF00756.20 EEQ31725.1 - 0.0023 17.6 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EEQ31725.1 - 0.039 14.5 0.2 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ31725.1 - 0.043 13.1 0.0 0.091 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ketoacyl-synt PF00109.26 EEQ31726.1 - 1e-73 248.1 0.1 1.7e-73 247.3 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EEQ31726.1 - 1.6e-62 210.6 2.5 7.1e-61 205.2 0.1 3.4 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 EEQ31726.1 - 2.4e-53 181.7 0.0 4.1e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EEQ31726.1 - 1.2e-47 162.6 0.0 1.8e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EEQ31726.1 - 3.4e-38 130.3 0.0 9.7e-38 128.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EEQ31726.1 - 1.2e-11 45.0 0.0 4e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EEQ31726.1 - 1.2e-08 34.6 0.1 7.5e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ31726.1 - 1.6e-06 27.8 0.0 4.3e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 EEQ31726.1 - 0.00042 20.1 0.3 0.0013 18.5 0.3 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.25 EEQ31726.1 - 0.00049 20.4 0.0 0.0016 18.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EEQ31726.1 - 0.0027 17.1 0.2 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Zn_clus PF00172.18 EEQ31727.1 - 1.9e-07 31.1 11.2 3.9e-07 30.1 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 EEQ31727.1 - 0.39 11.1 14.1 3.7 7.9 4.0 3.1 2 1 1 3 3 3 0 Opy2 protein Methyltransf_25 PF13649.6 EEQ31728.1 - 7.2e-10 39.4 0.0 1.5e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ31728.1 - 1e-07 32.5 0.0 7.5e-06 26.5 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ31728.1 - 3.9e-05 23.5 0.0 9e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ31728.1 - 4.4e-05 22.9 0.0 7.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EEQ31728.1 - 0.00013 21.9 0.0 0.0013 18.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ31728.1 - 0.00015 22.5 0.0 0.00028 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEQ31728.1 - 0.004 16.7 0.0 0.018 14.6 0.1 1.9 1 1 1 2 2 2 1 Methyltransferase small domain TehB PF03848.14 EEQ31728.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB SnoaL_2 PF12680.7 EEQ31729.1 - 0.00019 22.0 0.1 0.00064 20.3 0.1 1.8 1 1 0 1 1 1 1 SnoaL-like domain AMP-binding PF00501.28 EEQ31730.1 - 5.9e-149 496.3 0.0 2.7e-74 250.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EEQ31730.1 - 6.8e-83 278.9 0.0 2.2e-43 148.6 0.0 2.8 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EEQ31730.1 - 1.1e-23 83.4 0.0 4.7e-13 49.3 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ31730.1 - 6.2e-05 23.9 0.0 0.042 14.8 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EEQ31730.1 - 0.029 13.0 0.0 0.084 11.5 0.0 1.7 2 0 0 2 2 2 0 Transferase family Beta-lactamase PF00144.24 EEQ31731.1 - 2.9e-46 158.2 0.0 4.2e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EEQ31731.1 - 9.4e-07 29.3 0.0 1e-05 25.9 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3471) NDC10_II PF16787.5 EEQ31732.1 - 1.8e-36 125.8 0.0 9.2e-21 74.2 0.0 2.7 2 1 1 3 3 3 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 EEQ31732.1 - 1.6e-09 38.0 0.4 3.7e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes F-box PF00646.33 EEQ31733.1 - 6.5e-05 22.7 0.5 0.0052 16.6 0.0 3.4 3 0 0 3 3 3 1 F-box domain fn3 PF00041.21 EEQ31735.1 - 9.1e-11 42.0 1.4 7.2e-08 32.7 0.2 2.8 2 0 0 2 2 2 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.6 EEQ31735.1 - 4.7e-09 36.9 0.2 6.7e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Flavi_M PF01004.19 EEQ31735.1 - 0.085 12.6 0.6 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Lipase_GDSL PF00657.22 EEQ31735.1 - 0.096 12.7 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Methyltransf_16 PF10294.9 EEQ31736.1 - 2e-10 40.7 0.0 0.00014 21.7 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase LVIVD PF08309.11 EEQ31737.1 - 0.00016 20.9 0.9 0.087 12.2 0.0 3.7 4 0 0 4 4 4 1 LVIVD repeat Beta_propel PF09826.9 EEQ31737.1 - 0.011 14.6 0.4 0.048 12.5 0.4 2.1 1 1 0 1 1 1 0 Beta propeller domain AMP-binding PF00501.28 EEQ31740.1 - 6.3e-91 305.1 0.0 8.9e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ31740.1 - 8.8e-05 23.4 0.1 0.00022 22.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2975 PF11188.8 EEQ31741.1 - 0.031 14.2 3.3 0.048 13.5 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) NDT80_PhoG PF05224.12 EEQ31742.1 - 1.8e-40 139.2 0.1 2.8e-40 138.5 0.1 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family eIF3g PF12353.8 EEQ31743.1 - 3.4e-45 153.5 1.9 3.4e-45 153.5 1.9 1.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EEQ31743.1 - 3.4e-16 58.8 0.0 5.5e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 EEQ31743.1 - 0.015 15.6 0.2 0.035 14.4 0.2 1.6 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 EEQ31743.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif NMO PF03060.15 EEQ31744.1 - 2e-57 195.1 0.9 2.6e-57 194.7 0.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EEQ31744.1 - 1.5e-10 40.6 0.2 5e-09 35.6 0.2 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EEQ31744.1 - 2.4e-07 30.1 2.0 4e-07 29.4 2.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 EEQ31744.1 - 0.0081 15.4 0.2 0.013 14.7 0.2 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 EEQ31744.1 - 0.013 14.6 1.2 0.024 13.8 1.2 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase Pterin_bind PF00809.22 EEQ31745.1 - 4.3e-79 265.6 0.1 6e-79 265.2 0.1 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EEQ31745.1 - 4.8e-36 123.7 0.0 9.1e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ArfGap PF01412.18 EEQ31746.1 - 6.8e-35 119.7 0.5 1.2e-34 118.9 0.5 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.11 EEQ31747.1 - 1.5e-40 138.4 0.0 1.9e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EEQ31747.1 - 3.9e-07 29.8 0.0 7.7e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 MR_MLE_C PF13378.6 EEQ31748.1 - 6.4e-57 192.6 0.1 3.5e-56 190.2 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EEQ31748.1 - 1.1e-07 32.0 0.1 2.2e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PepSY PF03413.19 EEQ31748.1 - 0.036 14.6 0.2 0.099 13.2 0.2 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain MAAL_C PF07476.11 EEQ31748.1 - 0.037 13.2 0.0 0.09 11.9 0.0 1.6 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Aminotran_5 PF00266.19 EEQ31749.1 - 4.5e-28 98.3 0.0 6.9e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PWI PF01480.17 EEQ31750.1 - 1e-16 61.0 0.6 2.4e-16 59.8 0.6 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EEQ31750.1 - 0.045 13.6 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUD1_2 PF18457.1 EEQ31751.1 - 8.5e-59 198.5 0.7 1e-58 198.2 0.7 1.1 1 0 0 1 1 1 1 Up-Regulated in long-lived daf-2 NPCBM_assoc PF10633.9 EEQ31751.1 - 0.061 13.6 0.5 0.34 11.2 0.5 2.1 1 1 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase PGI PF00342.19 EEQ31753.1 - 4.5e-238 790.7 2.0 5.1e-238 790.5 2.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_S21 PF01165.20 EEQ31754.1 - 7.9e-11 41.5 2.4 1.5e-10 40.6 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Leu_Phe_trans PF03588.14 EEQ31754.1 - 0.11 12.0 1.1 0.31 10.5 1.3 1.7 1 1 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase Rhodanese PF00581.20 EEQ31755.1 - 1.6e-09 38.3 0.0 1.9e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_28 PF02636.17 EEQ31756.1 - 6.4e-83 278.4 0.0 8.1e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RRM_1 PF00076.22 EEQ31759.1 - 0.00015 21.5 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gypsy PF07253.11 EEQ31760.1 - 0.023 13.3 0.0 0.037 12.6 0.0 1.3 1 0 0 1 1 1 0 Gypsy protein HSP70 PF00012.20 EEQ31761.1 - 1.5e-262 872.2 15.1 1.7e-262 872.0 15.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ31761.1 - 6.8e-15 54.7 6.6 4.6e-13 48.7 2.4 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EEQ31761.1 - 0.00019 21.3 0.0 0.00047 19.9 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 EEQ31761.1 - 0.048 12.9 4.7 0.15 11.3 0.1 3.0 3 1 1 4 4 4 0 StbA protein Histone_HNS PF00816.21 EEQ31761.1 - 0.15 12.9 4.8 9.4 7.1 2.0 3.3 2 1 1 3 3 3 0 H-NS histone family FtsA PF14450.6 EEQ31761.1 - 0.17 12.3 8.6 2.1 8.8 1.5 4.0 3 2 0 3 3 3 0 Cell division protein FtsA Toxin-deaminase PF14424.6 EEQ31761.1 - 0.21 11.7 3.4 3 7.9 0.1 2.4 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases SMBP PF16785.5 EEQ31761.1 - 0.55 10.5 4.6 0.18 12.0 1.3 2.0 2 0 0 2 2 2 0 Small metal-binding protein DUF2415 PF10313.9 EEQ31762.1 - 5.9e-16 58.1 0.0 1.6e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) CAP_N PF01213.19 EEQ31762.1 - 0.75 9.2 7.0 1.3 8.4 7.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CD24 PF14984.6 EEQ31762.1 - 1.1 9.6 3.0 4.2 7.7 2.6 2.2 2 0 0 2 2 2 0 CD24 protein PRIMA1 PF16101.5 EEQ31762.1 - 1.1 9.3 5.2 2.5 8.1 5.2 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PigN PF04987.14 EEQ31763.1 - 0.0011 17.9 0.7 0.0011 17.9 0.7 2.0 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) DSHCT PF08148.12 EEQ31764.1 - 1.5e-51 174.4 0.5 3.9e-51 173.0 0.5 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EEQ31764.1 - 2.3e-41 140.8 0.0 4.3e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 EEQ31764.1 - 6.3e-17 61.9 0.0 1.4e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 EEQ31764.1 - 2.8e-16 60.3 0.0 6.8e-16 59.0 0.0 1.7 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 EEQ31764.1 - 7.3e-06 26.3 0.0 2e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ31764.1 - 0.00027 21.0 0.0 0.0007 19.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IBN_N PF03810.19 EEQ31765.1 - 7.9e-14 51.3 0.0 1.3e-11 44.3 0.0 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 EEQ31765.1 - 1.5e-06 27.3 0.0 3.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.6 EEQ31765.1 - 0.00014 22.2 0.1 0.42 11.0 0.0 3.5 2 1 1 3 3 3 2 HEAT repeats Xpo1 PF08389.12 EEQ31765.1 - 0.00061 19.9 0.4 0.021 14.9 0.0 3.4 2 1 0 2 2 2 1 Exportin 1-like protein GRIP PF01465.20 EEQ31765.1 - 0.00099 19.0 0.0 0.0093 15.9 0.0 2.8 1 1 0 1 1 1 1 GRIP domain RTP1_C1 PF10363.9 EEQ31765.1 - 0.005 17.0 0.1 0.13 12.4 0.1 3.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 CAS_CSE1 PF03378.15 EEQ31765.1 - 0.016 13.7 0.4 0.12 10.8 0.1 2.6 2 1 0 2 2 2 0 CAS/CSE protein, C-terminus Telomere_reg-2 PF10193.9 EEQ31765.1 - 0.09 13.2 0.3 0.45 11.0 0.2 2.3 2 0 0 2 2 2 0 Telomere length regulation protein Vac14_Fab1_bd PF12755.7 EEQ31765.1 - 0.18 12.4 1.2 1.9 9.2 0.0 3.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RRM_1 PF00076.22 EEQ31767.1 - 4.6e-08 32.8 0.0 1.1e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEQ31767.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EEQ31767.1 - 0.0073 16.2 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif ATG16 PF08614.11 EEQ31768.1 - 0.0098 16.1 2.1 0.0098 16.1 2.1 2.4 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) CENP-F_N PF10481.9 EEQ31768.1 - 0.085 12.5 4.8 0.16 11.5 4.8 1.7 1 1 0 1 1 1 0 Cenp-F N-terminal domain SlyX PF04102.12 EEQ31768.1 - 0.18 12.5 4.1 5.6 7.7 0.6 2.5 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 EEQ31768.1 - 0.42 10.4 3.3 0.38 10.6 0.5 2.0 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 EEQ31768.1 - 0.52 10.8 2.8 0.55 10.7 0.2 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ferlin_C PF16165.5 EEQ31769.1 - 8.9 6.2 8.4 8.4 6.3 2.2 2.4 2 0 0 2 2 2 0 Ferlin C-terminus DbpA PF03880.15 EEQ31770.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain SOG2 PF10428.9 EEQ31770.1 - 8.3 5.5 16.7 12 4.9 16.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.16 EEQ31771.1 - 2e-22 79.6 29.5 4.7e-21 75.1 10.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ31771.1 - 4.9e-10 38.9 0.6 4.9e-10 38.9 0.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Fungal_TACC PF12709.7 EEQ31772.1 - 2.4e-10 40.7 25.9 4.2e-08 33.5 4.5 4.6 3 1 2 5 5 5 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1664 PF07889.12 EEQ31772.1 - 0.0018 18.3 18.9 0.077 13.0 4.2 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) DUF745 PF05335.13 EEQ31772.1 - 0.0085 15.8 14.3 0.0085 15.8 14.3 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF745) AAA_13 PF13166.6 EEQ31772.1 - 0.011 14.4 27.5 0.18 10.4 9.8 2.3 1 1 1 2 2 2 0 AAA domain ZapB PF06005.12 EEQ31772.1 - 0.017 15.6 3.7 0.017 15.6 3.7 5.1 2 2 3 5 5 5 0 Cell division protein ZapB MscS_porin PF12795.7 EEQ31772.1 - 0.03 13.9 33.0 0.04 13.5 0.8 3.7 1 1 3 4 4 4 0 Mechanosensitive ion channel porin domain SEA PF01390.20 EEQ31772.1 - 0.06 13.4 0.6 0.5 10.5 0.1 2.5 2 0 0 2 2 2 0 SEA domain CALCOCO1 PF07888.11 EEQ31772.1 - 0.088 11.7 45.8 2.7 6.8 24.2 3.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 EEQ31772.1 - 0.27 10.6 30.5 0.21 10.9 8.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 EEQ31772.1 - 0.45 10.5 45.6 0.29 11.2 14.5 3.7 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4686 PF15742.5 EEQ31772.1 - 0.5 9.4 36.2 1 8.5 17.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Fib_alpha PF08702.10 EEQ31772.1 - 1.3 9.2 16.3 2.8 8.1 1.3 3.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.12 EEQ31772.1 - 1.8 8.6 4.6 1.8 8.5 0.0 3.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Uso1_p115_C PF04871.13 EEQ31772.1 - 2.2 8.6 48.4 7.6 6.9 8.4 4.4 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region FPP PF05911.11 EEQ31772.1 - 2.5 6.2 42.5 1.1 7.4 2.6 3.3 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil RasGAP_C PF03836.15 EEQ31772.1 - 3.2 7.9 13.6 0.48 10.6 4.3 3.2 1 1 1 3 3 3 0 RasGAP C-terminus DUF3450 PF11932.8 EEQ31772.1 - 4 6.7 34.1 1 8.6 11.5 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) DUF4201 PF13870.6 EEQ31772.1 - 4 7.1 27.3 4.1 7.1 6.7 3.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) Tropomyosin PF00261.20 EEQ31772.1 - 4.1 6.7 48.2 20 4.4 48.2 2.1 1 1 0 1 1 1 0 Tropomyosin GAS PF13851.6 EEQ31772.1 - 4.9 6.4 37.6 3.1 7.1 12.4 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FliE PF02049.18 EEQ31772.1 - 4.9 7.4 9.3 1.9 8.7 0.1 3.8 2 1 2 4 4 4 0 Flagellar hook-basal body complex protein FliE Z1 PF10593.9 EEQ31772.1 - 7.1 6.1 10.4 12 5.3 0.9 2.8 2 1 0 2 2 2 0 Z1 domain DUF4472 PF14739.6 EEQ31772.1 - 8 7.3 37.2 0.19 12.5 4.9 4.3 2 1 3 5 5 4 0 Domain of unknown function (DUF4472) FAD_binding_3 PF01494.19 EEQ31773.1 - 5.8e-07 29.1 0.1 4.4e-06 26.2 0.0 2.2 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 EEQ31773.1 - 0.00018 21.2 0.1 0.0003 20.5 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ31773.1 - 0.0011 19.1 0.3 0.01 16.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EEQ31773.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding TUDOR PF00567.24 EEQ31774.1 - 0.0022 18.0 0.0 0.0034 17.4 0.0 1.2 1 0 0 1 1 1 1 Tudor domain Fungal_trans PF04082.18 EEQ31775.1 - 2e-30 105.8 0.3 4.2e-30 104.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ31775.1 - 0.0046 17.1 18.0 0.0081 16.3 18.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sof1 PF04158.14 EEQ31775.1 - 0.048 13.9 0.2 0.14 12.5 0.2 1.7 1 0 0 1 1 1 0 Sof1-like domain MFS_1 PF07690.16 EEQ31776.1 - 4.1e-14 52.3 30.4 4.1e-14 52.3 30.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EEQ31776.1 - 1.2e-10 41.3 4.6 1.2e-10 41.3 4.6 2.8 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Amidohydro_1 PF01979.20 EEQ31777.1 - 1.7e-16 60.5 0.0 3e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EEQ31777.1 - 8.8e-12 45.2 0.7 1.2e-07 31.6 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family GMC_oxred_N PF00732.19 EEQ31778.1 - 1.4e-51 175.7 0.0 1.7e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EEQ31778.1 - 5.2e-36 124.3 0.0 7.9e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EEQ31778.1 - 3.9e-05 22.9 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EEQ31778.1 - 4e-05 22.9 0.0 0.096 11.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EEQ31778.1 - 6.8e-05 23.0 0.1 0.00021 21.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ31778.1 - 0.0007 19.3 0.1 0.0035 17.0 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ31778.1 - 0.0018 17.6 0.0 0.0041 16.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ31778.1 - 0.0089 16.6 0.2 0.66 10.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EEQ31778.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 EEQ31778.1 - 0.044 13.1 0.1 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EEQ31778.1 - 0.05 12.8 0.2 0.29 10.3 0.1 2.2 3 0 0 3 3 3 0 Thi4 family Aldedh PF00171.22 EEQ31779.1 - 5.6e-161 536.1 0.3 6.7e-161 535.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 EEQ31779.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family Glucosamine_iso PF01182.20 EEQ31780.1 - 1.5e-11 44.6 0.0 1.6e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.21 EEQ31781.1 - 8.8e-69 232.3 0.0 1.2e-68 231.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 EEQ31781.1 - 4.5e-06 26.9 0.0 1.2e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 EEQ31781.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.7 EEQ31781.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.12 EEQ31782.1 - 2.4e-40 138.7 0.0 2.4e-40 138.7 0.0 1.8 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family LCE PF14672.6 EEQ31782.1 - 0.06 13.9 0.9 0.22 12.2 0.9 1.9 1 0 0 1 1 1 0 Late cornified envelope Hexokinase_2 PF03727.16 EEQ31783.1 - 2.6e-52 177.6 0.0 4.8e-52 176.8 0.0 1.4 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 EEQ31783.1 - 1.3e-43 149.2 0.0 1.8e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase HNH_2 PF13391.6 EEQ31784.1 - 2.5e-10 40.3 0.0 1.1e-09 38.3 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease Astro_capsid_p PF12226.8 EEQ31784.1 - 5.8 6.0 13.1 8.8 5.4 13.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein p450 PF00067.22 EEQ31785.1 - 2e-43 148.9 0.0 3e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Hep_59 PF07052.11 EEQ31786.1 - 2.2e-14 54.1 0.0 2.2e-14 54.1 0.0 2.6 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 TRP PF06011.12 EEQ31787.1 - 2.8e-139 464.6 12.8 3.5e-139 464.2 12.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EEQ31787.1 - 5.6e-33 114.2 0.1 9.7e-33 113.5 0.1 1.4 1 0 0 1 1 1 1 ML-like domain DUF4337 PF14235.6 EEQ31787.1 - 0.069 13.3 0.1 0.26 11.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF2371 PF10177.9 EEQ31787.1 - 0.16 12.1 0.1 0.49 10.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) SCIMP PF15050.6 EEQ31787.1 - 2.3 8.7 4.1 42 4.6 0.2 3.8 3 1 1 4 4 4 0 SCIMP protein TFIIIC_sub6 PF10419.9 EEQ31788.1 - 1.4e-25 89.0 0.0 2.3e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain ELFV_dehydrog PF00208.21 EEQ31789.1 - 9.7e-61 205.6 0.0 1.4e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EEQ31789.1 - 3.1e-21 74.8 0.0 8.6e-15 53.4 0.0 2.4 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase MFS_1 PF07690.16 EEQ31790.1 - 4.4e-21 75.2 38.4 4.2e-17 62.1 38.7 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1418 PF07214.12 EEQ31790.1 - 0.75 9.7 0.0 0.75 9.7 0.0 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF1418) Myb_DNA-binding PF00249.31 EEQ31794.1 - 3.1e-31 107.3 9.6 1.3e-11 44.5 0.7 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ31794.1 - 5.1e-30 103.5 4.3 8.3e-15 54.8 1.8 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EEQ31794.1 - 7.8e-05 22.8 1.2 0.071 13.3 0.2 2.8 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EEQ31794.1 - 0.0009 19.1 0.2 0.95 9.4 0.0 2.6 2 1 1 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 EEQ31794.1 - 0.031 14.4 1.2 3.4 7.8 1.1 2.6 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EEQ31794.1 - 0.14 12.2 0.1 19 5.3 0.0 2.9 1 1 2 3 3 3 0 SLIDE PPR_2 PF13041.6 EEQ31795.1 - 1e-09 38.4 0.3 0.057 13.6 0.0 6.5 5 2 2 7 7 7 4 PPR repeat family PPR PF01535.20 EEQ31795.1 - 3.3e-05 23.8 3.0 23 5.5 0.0 6.6 6 0 0 6 6 6 1 PPR repeat PPR_3 PF13812.6 EEQ31795.1 - 0.031 14.3 1.6 5.4 7.2 0.0 4.1 5 0 0 5 5 5 0 Pentatricopeptide repeat domain TPR_14 PF13428.6 EEQ31795.1 - 0.12 13.3 0.0 93 4.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S18 PF01084.20 EEQ31796.1 - 3.7e-16 59.1 0.0 7.8e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 SPATIAL PF15256.6 EEQ31796.1 - 0.051 13.9 0.8 0.1 12.9 0.8 1.6 1 1 0 1 1 1 0 SPATIAL Cro PF09048.10 EEQ31796.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 2 0 0 2 2 2 0 Cro WD40 PF00400.32 EEQ31797.1 - 2.1e-35 120.1 28.5 0.00052 20.8 1.3 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ31797.1 - 1.4e-18 67.0 4.5 7.7e-06 26.1 0.0 6.2 4 3 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EEQ31797.1 - 0.001 18.4 0.0 0.013 14.9 0.0 2.3 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EEQ31797.1 - 0.0066 15.5 0.6 32 3.3 0.0 4.7 4 2 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_N PF14781.6 EEQ31797.1 - 0.027 14.4 0.0 0.088 12.7 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal IRF PF00605.17 EEQ31797.1 - 0.08 13.2 0.4 4.8 7.5 0.1 2.5 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor PD40 PF07676.12 EEQ31797.1 - 0.43 10.6 3.2 5 7.2 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Peptidase_M36 PF02128.15 EEQ31801.1 - 3.9e-156 519.9 7.0 4.8e-156 519.6 7.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EEQ31801.1 - 1.7e-18 66.1 4.1 3.5e-18 65.2 4.1 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EEQ31801.1 - 0.0081 16.0 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain IclR PF01614.18 EEQ31803.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial transcriptional regulator Methyltransf_25 PF13649.6 EEQ31804.1 - 1e-10 42.2 0.0 2.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ31804.1 - 1.5e-08 34.6 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ31804.1 - 9.4e-07 29.5 0.0 1.9e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ31804.1 - 2.7e-05 24.7 0.0 5.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ31804.1 - 7.9e-05 22.5 0.0 0.00034 20.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EEQ31804.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Alk_phosphatase PF00245.20 EEQ31806.1 - 1.2e-107 360.4 0.0 1.5e-107 360.2 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EEQ31806.1 - 3.2e-06 26.7 0.0 1.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Metalloenzyme superfamily FUSC_2 PF13515.6 EEQ31807.1 - 4.1e-30 104.5 9.4 4.1e-30 104.5 9.4 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 EEQ31807.1 - 0.019 13.8 13.2 0.16 10.8 0.0 3.5 4 0 0 4 4 4 0 Aluminium activated malate transporter ArAE_2 PF10334.9 EEQ31807.1 - 0.079 12.8 0.5 0.15 11.8 0.5 1.4 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 APH PF01636.23 EEQ31808.1 - 1.7e-16 60.9 0.5 4.1e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EEQ31808.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Choline_kinase PF01633.20 EEQ31808.1 - 0.047 13.3 0.4 0.21 11.2 0.2 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EEQ31808.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Oxidored_molyb PF00174.19 EEQ31809.1 - 1.7e-50 171.0 0.0 2.9e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EEQ31809.1 - 2.4e-38 131.3 0.4 2.4e-38 131.3 0.4 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 EEQ31809.1 - 1e-26 93.7 0.0 1.2e-25 90.2 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEQ31809.1 - 1e-16 61.1 0.0 2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EEQ31809.1 - 6.9e-16 58.2 0.2 3.1e-15 56.1 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EEQ31809.1 - 0.00052 20.2 0.2 0.043 13.9 0.0 3.3 3 1 1 4 4 4 1 Ferric reductase NAD binding domain UPF0270 PF06794.12 EEQ31809.1 - 0.18 11.9 0.7 0.43 10.7 0.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Beta-lactamase PF00144.24 EEQ31810.1 - 7e-23 81.4 1.7 1.3e-22 80.5 1.7 1.3 1 1 0 1 1 1 1 Beta-lactamase HNH_2 PF13391.6 EEQ31811.1 - 7.1e-10 38.9 0.0 1.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease zf-ANAPC11 PF12861.7 EEQ31812.1 - 8e-05 22.6 4.5 8e-05 22.6 4.5 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EEQ31812.1 - 0.00028 21.1 11.6 0.0013 18.9 11.7 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEQ31812.1 - 0.00099 19.4 14.9 0.012 16.0 14.9 2.3 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EEQ31812.1 - 0.068 13.2 7.8 0.15 12.1 7.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EEQ31812.1 - 0.18 11.7 5.1 0.48 10.3 5.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EEQ31812.1 - 0.19 11.9 6.0 0.6 10.3 6.1 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain PhoLip_ATPase_C PF16212.5 EEQ31813.1 - 3.8e-79 266.0 21.5 3.8e-79 266.0 21.5 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEQ31813.1 - 1.9e-18 65.9 0.3 4.8e-18 64.6 0.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EEQ31813.1 - 4.5e-12 45.9 0.0 2e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEQ31813.1 - 8.3e-11 42.6 1.6 6.6e-06 26.6 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEQ31813.1 - 0.00042 19.9 1.4 0.00087 18.9 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EEQ31813.1 - 0.05 13.3 0.5 0.14 11.9 0.5 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_efflux PF01545.21 EEQ31813.1 - 0.067 12.9 2.1 0.64 9.7 0.1 2.8 3 0 0 3 3 3 0 Cation efflux family MIP-T3_C PF17749.1 EEQ31813.1 - 9.4 6.2 6.6 18 5.3 0.9 2.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region PuR_N PF09182.10 EEQ31814.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Ank_2 PF12796.7 EEQ31815.1 - 6.7e-14 52.2 2.3 0.0017 18.9 0.1 6.0 4 1 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ31815.1 - 1.3e-13 51.2 2.7 0.028 15.0 0.0 7.5 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ31815.1 - 5.7e-13 48.8 3.4 0.025 14.9 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ31815.1 - 7.6e-10 38.2 5.1 0.091 13.4 0.0 7.1 7 2 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 EEQ31815.1 - 3.7e-09 36.6 1.0 0.24 11.9 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat RicinB_lectin_2 PF14200.6 EEQ31820.1 - 5.1e-05 23.9 0.3 0.035 14.8 0.1 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ank_3 PF13606.6 EEQ31822.1 - 1.2e-09 37.6 0.0 0.023 15.2 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EEQ31822.1 - 1.4e-09 38.4 0.0 3.2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ31822.1 - 4.4e-08 33.5 0.0 1.4e-07 31.9 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EEQ31822.1 - 5.1e-08 33.0 0.0 0.022 15.2 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat AAA_16 PF13191.6 EEQ31822.1 - 2.8e-06 27.8 0.0 6.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ31822.1 - 8.9e-06 26.0 0.0 3.2e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EEQ31822.1 - 9.5e-05 22.4 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 EEQ31822.1 - 0.012 15.9 0.0 0.16 12.3 0.0 2.6 1 1 2 3 3 3 0 Ankyrin repeats (many copies) AAA_29 PF13555.6 EEQ31822.1 - 0.018 14.8 0.0 0.072 12.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EEQ31822.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EEQ31822.1 - 0.029 13.6 0.0 0.93 8.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NACHT_sigma PF17106.5 EEQ31822.1 - 0.059 13.5 5.8 0.12 12.6 5.8 1.5 1 0 0 1 1 1 0 Sigma domain on NACHT-NTPases VCH_CASS14 PF18315.1 EEQ31822.1 - 0.065 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain Viral_helicase1 PF01443.18 EEQ31822.1 - 0.19 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SesA PF17107.5 EEQ31823.1 - 1.6e-30 105.8 0.0 4.6e-30 104.3 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 EEQ31823.1 - 2.4e-18 66.0 11.2 4.1e-18 65.3 11.2 1.4 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases Glyco_hydro_18 PF00704.28 EEQ31825.1 - 2.4e-49 168.8 0.7 4.4e-49 167.9 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 EEQ31825.1 - 7.3e-27 93.6 0.6 2.2e-26 92.1 0.6 1.9 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.20 EEQ31825.1 - 2.9e-06 27.2 0.1 0.081 13.0 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 EEQ31825.1 - 2.7e-05 24.5 8.8 2.7e-05 24.5 8.8 3.4 4 0 0 4 4 4 1 Chitin recognition protein LysM PF01476.20 EEQ31827.1 - 5.3e-16 58.4 0.6 0.00027 20.9 0.0 3.2 3 0 0 3 3 3 3 LysM domain UPF0203 PF05254.12 EEQ31827.1 - 0.75 10.1 3.3 13 6.2 0.8 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) SAGA-Tad1 PF12767.7 EEQ31828.1 - 4.3e-55 187.0 0.0 6e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.12 EEQ31829.1 - 1.8e-53 180.9 7.9 4.5e-53 179.6 7.9 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EEQ31829.1 - 8.4e-25 85.3 19.0 0.013 16.3 0.0 12.6 6 4 7 13 13 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ31829.1 - 1.9e-16 60.3 3.9 0.025 15.1 0.2 8.9 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ31829.1 - 6.9e-12 44.5 2.4 0.13 12.5 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ31829.1 - 3.9e-09 36.0 1.8 0.068 13.4 0.0 7.1 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ31829.1 - 2.5e-07 30.6 0.1 0.71 10.4 0.0 7.4 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ31829.1 - 5.7e-06 26.9 8.4 0.1 13.3 0.1 6.7 6 1 1 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.8 EEQ31829.1 - 6.1e-06 25.4 6.4 0.011 14.6 0.0 4.8 4 1 1 5 5 5 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 EEQ31829.1 - 0.0001 22.0 2.0 0.5 10.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ31829.1 - 0.00011 22.3 1.5 0.062 13.4 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ31829.1 - 0.00053 19.6 0.0 18 5.1 0.0 5.0 5 0 0 5 5 5 0 TPR repeat TPR_12 PF13424.6 EEQ31829.1 - 0.0013 19.0 1.0 24 5.3 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ31829.1 - 0.12 12.4 1.3 67 3.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ31829.1 - 3.6 8.4 7.6 1.1e+02 3.8 0.1 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat PTPRCAP PF15713.5 EEQ31829.1 - 3.7 7.8 10.9 1.3 9.2 7.0 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RrnaAD PF00398.20 EEQ31830.1 - 4.3e-64 216.1 0.0 5.7e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EEQ31830.1 - 1.7e-07 31.8 0.0 4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ31830.1 - 1.3e-05 25.8 0.0 3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EEQ31830.1 - 8.5e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EEQ31830.1 - 0.00022 20.6 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EEQ31830.1 - 0.001 18.9 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEQ31830.1 - 0.0011 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EEQ31830.1 - 0.0023 18.6 0.0 0.007 17.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ31830.1 - 0.0083 15.9 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EEQ31830.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 EEQ31830.1 - 0.012 15.1 0.6 0.033 13.6 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EEQ31830.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 EEQ31830.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 EEQ31830.1 - 0.038 13.6 0.2 0.089 12.4 0.0 1.7 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 EEQ31830.1 - 0.038 13.4 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.12 EEQ31830.1 - 0.047 12.8 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase AAA_31 PF13614.6 EEQ31830.1 - 0.1 12.5 0.5 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Methyltransf_18 PF12847.7 EEQ31830.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.18 EEQ31831.1 - 2.1e-50 171.4 0.0 6e-50 169.9 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain FXR_C3 PF16097.5 EEQ31832.1 - 0.14 12.9 4.2 0.12 13.1 2.9 1.6 1 1 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 3 RRM_1 PF00076.22 EEQ31833.1 - 1.3e-32 111.4 0.3 2.6e-15 56.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ31833.1 - 1.7e-10 40.9 0.2 0.00062 19.8 0.1 3.0 2 2 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 EEQ31833.1 - 0.0029 17.6 0.1 2.1 8.4 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 EEQ31833.1 - 0.011 15.7 0.1 5 7.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Phytochelatin PF05023.14 EEQ31833.1 - 0.096 11.9 1.5 1.3 8.2 0.0 2.7 3 0 0 3 3 3 0 Phytochelatin synthase MCRS_N PF13325.6 EEQ31833.1 - 2.3 8.2 4.6 5.7 6.9 4.6 1.6 1 1 0 1 1 1 0 N-terminal region of micro-spherule protein JmjC PF02373.22 EEQ31834.1 - 5e-09 36.6 0.0 6.5e-08 33.0 0.0 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EEQ31834.1 - 2.2e-08 34.1 0.0 5.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain JHD PF17811.1 EEQ31834.1 - 9.3e-07 29.3 0.3 1.9e-06 28.4 0.3 1.5 1 0 0 1 1 1 1 Jumonji helical domain PHD PF00628.29 EEQ31834.1 - 9.7e-07 28.6 9.6 9.7e-07 28.6 9.6 2.5 3 0 0 3 3 3 1 PHD-finger Zn_clus PF00172.18 EEQ31834.1 - 2.3 8.4 28.1 0.05 13.7 4.6 3.2 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD_2 PF13831.6 EEQ31834.1 - 8.3 6.1 10.8 6.5 6.4 8.6 2.1 2 0 0 2 2 2 0 PHD-finger COG4 PF08318.12 EEQ31836.1 - 2.8e-121 404.7 0.0 3.8e-121 404.3 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein SIR2 PF02146.17 EEQ31837.1 - 1.6e-57 194.3 0.0 2.8e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF2815 PF10991.8 EEQ31837.1 - 0.08 12.9 1.0 0.11 12.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) TPP_enzyme_M PF00205.22 EEQ31837.1 - 0.11 12.2 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Hexokinase_2 PF03727.16 EEQ31838.1 - 1.6e-82 276.6 0.0 2.2e-82 276.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EEQ31838.1 - 6.9e-73 244.8 0.0 9e-73 244.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase ANAPC4_WD40 PF12894.7 EEQ31839.1 - 0.0015 18.8 0.1 2.7 8.3 0.2 4.0 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ31839.1 - 0.0069 17.2 5.2 2.1 9.3 0.0 4.8 6 0 0 6 6 6 1 WD domain, G-beta repeat PCNP PF15473.6 EEQ31839.1 - 0.15 12.8 0.0 0.15 12.8 0.0 2.2 3 0 0 3 3 3 0 PEST, proteolytic signal-containing nuclear protein family PikAIV_N PF18605.1 EEQ31839.1 - 0.7 9.5 7.4 3.7 7.2 1.5 2.9 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain STIMATE PF12400.8 EEQ31840.1 - 1.3e-37 129.1 6.4 2.2e-37 128.4 6.4 1.4 1 0 0 1 1 1 1 STIMATE family RRM_1 PF00076.22 EEQ31841.1 - 3e-08 33.4 0.4 1.1e-07 31.5 0.3 2.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ31841.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ammonium_transp PF00909.21 EEQ31842.1 - 1.5e-114 382.9 27.7 1.7e-114 382.6 27.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.20 EEQ31843.1 - 3.8e-46 156.9 0.1 3.8e-46 156.9 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EEQ31843.1 - 6.4e-39 133.5 0.5 6.4e-39 133.5 0.5 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EEQ31843.1 - 2.3e-21 77.1 1.2 3.1e-20 73.4 0.5 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEQ31843.1 - 5.3e-21 74.1 0.0 1.3e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EEQ31843.1 - 6.7e-12 45.3 0.0 1.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEQ31843.1 - 1.3e-05 25.1 1.6 0.00039 20.3 0.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 EEQ31844.1 - 1.3e-37 128.3 0.0 2.5e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EEQ31844.1 - 2.4e-07 29.9 0.3 6.9e-07 28.5 0.3 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Ion_trans PF00520.31 EEQ31845.1 - 0.003 16.8 0.2 0.0036 16.6 0.2 1.1 1 0 0 1 1 1 1 Ion transport protein DUF4013 PF13197.6 EEQ31845.1 - 0.046 13.6 5.5 0.062 13.1 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Ank_2 PF12796.7 EEQ31846.1 - 5.6e-59 196.7 7.9 2.2e-15 57.0 0.1 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ31846.1 - 1.3e-49 165.5 6.2 1.5e-09 37.9 0.1 8.5 3 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ31846.1 - 1.8e-45 152.7 7.7 1.1e-07 32.2 0.0 8.6 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 EEQ31846.1 - 1e-43 145.9 18.8 2.5e-07 30.8 0.2 10.6 10 0 0 10 10 10 10 Ankyrin repeat Ank_3 PF13606.6 EEQ31846.1 - 3.2e-38 125.4 8.7 0.0013 19.0 0.0 11.1 11 0 0 11 11 11 8 Ankyrin repeat Rpr2 PF04032.16 EEQ31846.1 - 0.26 11.6 2.1 0.78 10.1 2.1 1.8 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain APH PF01636.23 EEQ31848.1 - 2.4e-09 37.5 0.4 2.5e-08 34.2 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ31848.1 - 0.041 12.7 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EEQ31848.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nterm_IS4 PF13006.7 EEQ31849.1 - 0.096 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Peptidase_S8 PF00082.22 EEQ31850.1 - 1.2e-15 57.6 0.0 2.7e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Subtilase family DGF-1_C PF11040.8 EEQ31850.1 - 0.19 11.8 1.5 0.46 10.5 0.7 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus AAA_12 PF13087.6 EEQ31851.1 - 1.1e-42 145.9 0.0 2.6e-42 144.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEQ31851.1 - 5.6e-22 78.8 0.0 1.2e-21 77.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEQ31851.1 - 6.5e-06 26.0 0.0 0.001 18.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEQ31851.1 - 1.7e-05 25.2 0.0 0.00032 21.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EEQ31851.1 - 0.00026 21.0 0.0 0.00056 19.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EEQ31851.1 - 0.00028 20.3 0.0 0.014 14.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EEQ31851.1 - 0.02 14.9 0.0 0.073 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 EEQ31851.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Helicase_RecD PF05127.14 EEQ31851.1 - 0.064 13.1 0.0 0.32 10.8 0.0 2.1 2 1 0 2 2 2 0 Helicase Mg_chelatase PF01078.21 EEQ31851.1 - 0.071 12.5 0.7 0.17 11.2 0.0 1.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATPgrasp_N PF18130.1 EEQ31852.1 - 2e-17 63.5 0.2 4.5e-17 62.4 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain Zn_clus PF00172.18 EEQ31855.1 - 0.0037 17.4 9.0 0.0037 17.4 9.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EEQ31855.1 - 0.028 14.4 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold CCDC14 PF15254.6 EEQ31855.1 - 0.88 8.2 10.6 0.017 13.8 3.2 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 14 Flavokinase PF01687.17 EEQ31856.1 - 5.4e-31 107.2 0.0 7e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase RSN1_7TM PF02714.15 EEQ31857.1 - 1.5e-84 283.6 30.2 1.5e-84 283.6 30.2 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EEQ31857.1 - 1.7e-47 161.0 1.7 1.7e-47 161.0 1.7 3.3 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EEQ31857.1 - 3.8e-28 98.9 0.8 6.8e-16 59.0 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EEQ31857.1 - 1.5e-13 50.7 1.0 4.3e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter BAR_3 PF16746.5 EEQ31857.1 - 0.19 11.4 4.3 0.32 10.7 4.3 1.2 1 0 0 1 1 1 0 BAR domain of APPL family R3H PF01424.22 EEQ31857.1 - 7.2 6.7 6.1 1.1 9.3 0.5 2.4 3 0 0 3 3 3 0 R3H domain SnoaL_2 PF12680.7 EEQ31858.1 - 2e-07 31.6 0.0 3.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EEQ31858.1 - 2e-05 24.4 0.0 3.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.18 EEQ31858.1 - 0.047 13.2 0.1 1.8 8.1 0.1 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Indigoidine_A PF04227.12 EEQ31859.1 - 3.4e-106 354.9 1.4 2.5e-105 352.0 1.4 2.0 1 1 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EEQ31859.1 - 1.4e-13 50.8 0.1 8.6e-07 28.6 0.0 3.3 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.14 EEQ31860.1 - 1.1e-143 479.7 0.1 1.2e-143 479.5 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I VTC PF09359.10 EEQ31861.1 - 2.9e-100 335.2 0.5 4.9e-100 334.5 0.5 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EEQ31861.1 - 2.6e-12 47.0 2.8 2.6e-12 47.0 2.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EEQ31861.1 - 1.4e-11 45.0 8.4 5.3e-06 26.6 0.0 3.1 2 1 0 2 2 2 2 SPX domain MCM PF00493.23 EEQ31862.1 - 4.7e-102 339.8 0.0 6.8e-102 339.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEQ31862.1 - 2e-36 124.6 0.2 3.6e-36 123.8 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEQ31862.1 - 1.3e-28 99.2 2.3 3.1e-28 98.0 2.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ31862.1 - 3.4e-18 66.2 0.0 1.3e-17 64.3 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ31862.1 - 8.3e-06 25.3 0.0 0.00026 20.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ31862.1 - 2.5e-05 24.3 0.1 0.00011 22.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEQ31862.1 - 0.0015 18.4 0.0 0.0093 15.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.7 EEQ31863.1 - 0.00041 20.9 0.1 0.14 12.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ31863.1 - 0.0063 17.1 0.0 2.5 8.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EEQ31863.1 - 0.015 15.7 0.0 0.055 13.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat LHH PF14411.6 EEQ31863.1 - 0.1 12.8 0.8 2.3 8.5 0.2 2.4 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH DUF3632 PF12311.8 EEQ31865.1 - 0.00048 20.6 0.0 0.00075 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Band_7 PF01145.25 EEQ31867.1 - 7.5e-23 81.4 6.3 1.3e-22 80.7 6.3 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.6 EEQ31868.1 - 2.3e-32 111.2 2.5 2.3e-32 111.2 2.5 2.2 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EEQ31868.1 - 7.1e-20 70.6 0.0 1.2e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EEQ31868.1 - 7.5e-15 54.2 5.3 4.5e-14 51.8 5.3 2.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EEQ31868.1 - 0.0095 16.0 0.1 1 9.5 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif Spo7_2_N PF15407.6 EEQ31868.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_Rrp7 PF17799.1 EEQ31868.1 - 0.02 14.7 0.0 2.2 8.1 0.0 2.3 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EEQ31868.1 - 0.058 13.3 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Occluded RNA-recognition motif DNA_methylase PF00145.17 EEQ31869.1 - 7.4e-17 61.7 0.0 1.3e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase SNF2_N PF00176.23 EEQ31869.1 - 1.3e-12 47.1 0.0 8.5e-12 44.4 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 EEQ31869.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ31869.1 - 0.0017 18.6 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-piccolo PF05715.13 EEQ31869.1 - 0.11 12.7 2.8 0.33 11.1 2.8 1.8 1 0 0 1 1 1 0 Piccolo Zn-finger 2Fe-2S_thioredx PF01257.19 EEQ31870.1 - 1.8e-54 183.5 0.0 2.4e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin UDPG_MGDP_dh PF00984.19 EEQ31870.1 - 0.079 13.2 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain DUF4139 PF13598.6 EEQ31871.1 - 6.1e-28 98.0 0.0 1.4e-27 96.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EEQ31871.1 - 3.3e-22 78.7 4.3 3.6e-20 72.2 0.0 2.7 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) Peptidase_C57 PF03290.13 EEQ31871.1 - 0.038 12.7 0.3 0.056 12.2 0.3 1.1 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase DUF2106 PF09879.9 EEQ31871.1 - 0.17 11.4 0.1 0.54 9.8 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) TPR_MLP1_2 PF07926.12 EEQ31871.1 - 0.33 11.0 12.2 0.7 10.0 12.2 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 EEQ31871.1 - 1.1 7.1 2.9 1.6 6.6 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Abhydrolase_2 PF02230.16 EEQ31872.1 - 3.9e-18 66.0 0.0 2.3e-13 50.5 0.0 3.6 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Sulphotransf PF09037.10 EEQ31872.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Stf0 sulphotransferase Sua5_yciO_yrdC PF01300.18 EEQ31873.1 - 5e-55 185.8 0.3 2.3e-54 183.6 0.0 1.9 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 EEQ31873.1 - 8.5e-30 104.1 0.0 1.9e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding FbpA PF05833.11 EEQ31874.1 - 1.1e-36 126.6 3.7 2.3e-36 125.5 3.7 1.5 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 EEQ31874.1 - 1.3e-36 124.7 0.0 1.3e-36 124.7 0.0 3.3 3 0 0 3 3 3 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 EEQ31874.1 - 1e-26 93.7 0.0 2.4e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain Clat_adaptor_s PF01217.20 EEQ31875.1 - 2.1e-13 50.4 0.0 4.3e-12 46.2 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain TSC22 PF01166.18 EEQ31876.1 - 0.26 11.6 2.3 0.64 10.4 2.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF948 PF06103.11 EEQ31877.1 - 0.25 11.6 0.8 0.67 10.3 0.8 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1515 PF07439.11 EEQ31877.1 - 0.34 11.0 9.0 0.11 12.5 4.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) IMD PF08397.11 EEQ31877.1 - 0.37 10.1 7.6 0.35 10.2 4.0 2.0 1 1 1 2 2 2 0 IRSp53/MIM homology domain Not3 PF04065.15 EEQ31877.1 - 0.47 9.8 18.8 0.19 11.1 9.2 2.9 2 1 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component FAM76 PF16046.5 EEQ31877.1 - 1.6 8.0 11.0 0.24 10.7 5.0 2.3 2 0 0 2 2 2 0 FAM76 protein Pox_A_type_inc PF04508.12 EEQ31877.1 - 6.3 6.8 9.0 4.8 7.2 2.7 3.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.11 EEQ31877.1 - 7.5 7.0 12.9 15 6.0 0.1 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) UPF0731 PF14982.6 EEQ31878.1 - 0.031 14.4 1.2 0.36 11.0 0.0 2.8 3 0 0 3 3 3 0 UPF0731 family Ribosomal_L16 PF00252.18 EEQ31880.1 - 4.6e-43 146.4 0.1 6.5e-43 145.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e BPL_N PF09825.9 EEQ31882.1 - 6.2e-10 38.7 0.0 1.3e-07 31.1 0.1 2.1 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal FAD_binding_2 PF00890.24 EEQ31883.1 - 5.2e-81 272.8 0.1 6.2e-81 272.6 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EEQ31883.1 - 5.7e-09 35.8 0.6 2.3e-08 33.8 0.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EEQ31883.1 - 1.3e-07 31.5 1.6 5.5e-07 29.5 1.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ31883.1 - 3.8e-07 30.2 3.0 1.1e-06 28.7 3.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EEQ31883.1 - 5e-07 28.8 0.2 9.4e-07 27.9 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EEQ31883.1 - 2.7e-06 26.8 0.1 5.2e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EEQ31883.1 - 2.5e-05 23.6 0.2 0.00021 20.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ31883.1 - 0.00015 21.2 0.1 0.00026 20.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EEQ31883.1 - 0.00072 18.9 0.2 0.0041 16.4 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EEQ31883.1 - 0.075 12.1 0.4 0.12 11.4 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EEQ31883.1 - 0.086 12.1 0.4 0.17 11.1 0.4 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 EEQ31883.1 - 0.15 11.1 2.0 0.23 10.5 2.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ABC_tran PF00005.27 EEQ31884.1 - 1.3e-06 28.9 0.1 2.6e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.6 EEQ31884.1 - 0.00066 19.5 0.1 0.00099 18.9 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EEQ31884.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ31884.1 - 0.039 13.7 0.1 0.082 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ31884.1 - 0.052 13.5 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 EEQ31884.1 - 0.13 12.3 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Methyltransf_2 PF00891.18 EEQ31885.1 - 9.4e-13 47.9 0.0 1.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain KDGP_aldolase PF07071.11 EEQ31885.1 - 0.0031 17.4 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 KDGP aldolase Dimerisation PF08100.11 EEQ31885.1 - 0.024 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_25 PF13649.6 EEQ31886.1 - 9.6e-31 106.4 0.0 7.8e-17 61.8 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ31886.1 - 2.2e-30 105.1 0.0 3.4e-14 53.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ31886.1 - 1.8e-19 70.0 0.0 9.1e-11 41.8 0.0 3.3 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ31886.1 - 2.3e-18 66.6 0.0 9.4e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ31886.1 - 7.5e-15 55.5 0.0 3.2e-08 34.2 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain MetW PF07021.12 EEQ31886.1 - 8.2e-11 41.8 0.0 6.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW CMAS PF02353.20 EEQ31886.1 - 9.8e-11 41.4 0.0 1.7e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EEQ31886.1 - 5.3e-09 35.8 0.0 6.2e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family NodS PF05401.11 EEQ31886.1 - 3.7e-08 33.2 0.0 1.5e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.14 EEQ31886.1 - 5.1e-07 29.4 0.0 0.00065 19.3 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase small domain PrmA PF06325.13 EEQ31886.1 - 2.4e-05 23.9 0.0 0.015 14.7 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 EEQ31886.1 - 0.00019 20.9 0.0 0.00083 18.8 0.0 2.0 2 0 0 2 2 2 1 Tellurite resistance protein TehB GidB PF02527.15 EEQ31886.1 - 0.00033 20.0 0.0 0.35 10.2 0.0 2.4 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.17 EEQ31886.1 - 0.00063 19.0 0.0 0.011 15.0 0.0 2.6 3 0 0 3 3 3 1 NNMT/PNMT/TEMT family Methyltransf_15 PF09445.10 EEQ31886.1 - 0.0015 18.2 0.0 0.004 16.7 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 EEQ31886.1 - 0.0015 18.7 0.0 0.014 15.5 0.0 2.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EEQ31886.1 - 0.011 15.4 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 EEQ31886.1 - 0.012 14.7 0.0 0.4 9.7 0.0 2.5 2 1 0 2 2 2 0 DREV methyltransferase TetR_N PF00440.23 EEQ31886.1 - 0.02 14.7 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Methyltransf_32 PF13679.6 EEQ31886.1 - 0.02 14.9 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 EEQ31886.1 - 0.044 13.7 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 EEQ31886.1 - 0.047 13.2 0.0 1 8.8 0.0 2.7 3 0 0 3 3 3 0 Putative methyltransferase Pox_MCEL PF03291.16 EEQ31886.1 - 0.049 12.7 0.0 0.65 9.0 0.0 2.2 1 1 1 2 2 2 0 mRNA capping enzyme Spermine_synth PF01564.17 EEQ31886.1 - 0.056 12.9 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Spermine/spermidine synthase domain RrnaAD PF00398.20 EEQ31886.1 - 0.16 11.0 0.0 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 EEQ31886.1 - 0.19 11.4 0.1 7.7 6.2 0.0 2.6 3 0 0 3 3 3 0 Met-10+ like-protein p450 PF00067.22 EEQ31887.1 - 1.1e-37 129.9 0.0 1.5e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 EEQ31888.1 - 4.9e-19 69.1 0.0 2e-18 67.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EEQ31888.1 - 0.00031 20.5 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 EEQ31888.1 - 0.00051 20.5 0.1 0.0035 17.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EEQ31888.1 - 0.00097 19.2 0.0 0.0027 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ31888.1 - 0.0032 17.8 0.2 0.036 14.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ31888.1 - 0.014 16.0 0.0 0.046 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EEQ31888.1 - 0.018 14.7 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_7 PF12775.7 EEQ31888.1 - 0.031 13.8 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EEQ31888.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EEQ31888.1 - 0.055 13.6 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EEQ31888.1 - 0.084 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EEQ31888.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FA_hydroxylase PF04116.13 EEQ31889.1 - 2.3e-22 79.7 13.0 2.3e-22 79.7 13.0 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HA2 PF04408.23 EEQ31890.1 - 1.4e-20 73.6 0.1 1.4e-20 73.6 0.1 3.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ31890.1 - 3.9e-12 46.5 0.0 1.1e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EEQ31890.1 - 6.9e-12 45.6 0.0 2e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.6 EEQ31890.1 - 0.0027 17.4 0.0 0.0073 16.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ31890.1 - 0.027 14.8 0.0 0.079 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEQ31890.1 - 0.12 12.9 0.0 0.39 11.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Zn_clus PF00172.18 EEQ31891.1 - 4.3e-09 36.3 12.2 7.9e-09 35.5 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 EEQ31892.1 - 1.4e-39 135.8 3.5 2.3e-39 135.2 3.5 1.3 1 0 0 1 1 1 1 RTA1 like protein ABC2_membrane_5 PF13346.6 EEQ31892.1 - 3 7.3 9.1 0.054 13.0 1.3 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Fungal_lectin PF07938.12 EEQ31893.1 - 5.6e-116 387.1 0.8 8.2e-93 311.1 0.1 2.0 1 1 1 2 2 2 2 Fungal fucose-specific lectin TauD PF02668.16 EEQ31894.1 - 1.1e-30 107.4 0.0 1.4e-30 107.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Complex1_LYR_2 PF13233.6 EEQ31896.1 - 7.7e-20 71.4 0.0 9.6e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EEQ31896.1 - 2.9e-09 36.8 0.1 5.1e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MTS PF05175.14 EEQ31897.1 - 0.0033 17.0 0.2 0.36 10.3 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain LSM PF01423.22 EEQ31898.1 - 4.2e-17 61.6 0.0 5.3e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEQ31898.1 - 0.0043 17.2 0.0 0.0056 16.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain F-box PF00646.33 EEQ31899.1 - 0.00041 20.1 0.0 0.011 15.6 0.0 2.8 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 EEQ31899.1 - 0.00049 19.9 0.0 0.0089 15.9 0.0 2.5 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 EEQ31900.1 - 5.7e-20 71.8 0.0 1.4e-14 54.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31900.1 - 2.1e-07 30.5 0.1 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_S13_N PF08069.12 EEQ31900.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain zf-C2H2 PF00096.26 EEQ31902.1 - 5.3e-06 26.6 2.4 0.033 14.6 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_ribbon_recom PF13408.6 EEQ31902.1 - 0.041 14.4 0.4 0.081 13.5 0.4 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_4 PF13894.6 EEQ31902.1 - 0.24 12.3 12.0 0.44 11.5 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Ank_2 PF12796.7 EEQ31904.1 - 7.7e-28 96.9 0.0 1.1e-07 32.3 0.0 4.7 3 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ31904.1 - 2.3e-23 82.2 0.9 3.3e-07 30.7 0.1 6.6 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ31904.1 - 3e-20 70.1 5.5 0.00017 21.7 0.2 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EEQ31904.1 - 5.9e-17 61.5 1.9 0.0027 18.0 0.1 6.9 5 3 3 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 EEQ31904.1 - 4.8e-16 58.4 8.5 1.6e-05 25.1 0.7 7.5 7 0 0 7 7 7 3 Ankyrin repeat DUF3447 PF11929.8 EEQ31904.1 - 0.075 13.0 0.1 0.63 10.0 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) GTP_EFTU PF00009.27 EEQ31907.1 - 3.6e-09 36.4 0.0 1.5e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ31907.1 - 0.00017 21.5 0.4 0.081 12.8 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 EEQ31907.1 - 0.007 16.9 0.2 0.016 15.7 0.2 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EEQ31907.1 - 0.014 15.8 0.3 0.045 14.1 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EEQ31907.1 - 0.074 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EEQ31907.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pkr1 PF08636.10 EEQ31908.1 - 5.9e-29 100.0 4.5 2e-28 98.3 4.5 2.0 1 0 0 1 1 1 1 ER protein Pkr1 Cullin PF00888.22 EEQ31908.1 - 7.3e-23 81.0 0.4 1.1e-22 80.4 0.4 1.1 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EEQ31908.1 - 2.8e-22 79.0 0.3 7.1e-22 77.7 0.3 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Phage_Gp23 PF10669.9 EEQ31908.1 - 0.087 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) NADH5_C PF06455.11 EEQ31908.1 - 0.68 9.5 3.4 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus SNF2_N PF00176.23 EEQ31909.1 - 2e-31 109.0 0.5 1.9e-29 102.5 0.1 3.0 2 1 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 EEQ31909.1 - 4.6e-05 23.5 0.0 0.00016 21.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ31909.1 - 0.1 12.9 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EEQ31909.1 - 0.13 11.4 0.1 0.25 10.5 0.1 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Thioredoxin PF00085.20 EEQ31910.1 - 6e-28 96.9 0.0 6.8e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EEQ31910.1 - 5.6e-08 33.2 0.1 8.2e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 EEQ31910.1 - 3e-06 27.0 0.2 0.00061 19.5 0.1 2.0 1 1 1 2 2 2 2 Redoxin Thioredoxin_8 PF13905.6 EEQ31910.1 - 1.4e-05 25.3 0.0 0.012 15.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EEQ31910.1 - 0.00031 20.6 0.1 0.00058 19.8 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EEQ31910.1 - 0.00061 19.6 0.0 0.00068 19.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EEQ31910.1 - 0.0008 18.8 0.0 0.00084 18.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 EEQ31910.1 - 0.01 16.0 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin HyaE PF07449.11 EEQ31910.1 - 0.024 14.6 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 EEQ31910.1 - 0.045 13.9 0.1 0.065 13.4 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_6 PF13848.6 EEQ31910.1 - 0.1 12.5 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain APH PF01636.23 EEQ31911.1 - 0.0027 17.7 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.7 EEQ31912.1 - 4.8e-09 36.0 1.3 1.1e-08 34.8 1.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ31912.1 - 9.6e-06 25.3 0.6 2.6e-05 23.9 0.6 1.7 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 EEQ31912.1 - 0.0054 16.8 0.2 0.91 9.8 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ31912.1 - 0.0084 15.8 0.5 0.062 13.0 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 EEQ31912.1 - 0.076 12.9 0.1 0.64 9.9 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.27 EEQ31913.1 - 2.8e-60 200.3 2.8 1.5e-21 76.1 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein KAR9 PF08580.10 EEQ31915.1 - 9.2e-237 787.9 2.5 9.2e-237 787.9 2.5 2.2 2 1 0 2 2 2 1 Yeast cortical protein KAR9 Astro_capsid_p PF12226.8 EEQ31916.1 - 0.023 13.9 3.7 0.033 13.4 3.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4746 PF15928.5 EEQ31916.1 - 0.22 10.9 6.2 0.36 10.2 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DivIVA PF05103.13 EEQ31916.1 - 8.3 6.5 13.0 15 5.7 13.0 1.3 1 0 0 1 1 1 0 DivIVA protein polyprenyl_synt PF00348.17 EEQ31917.1 - 6.4e-63 212.2 0.0 8.4e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Translin PF01997.16 EEQ31917.1 - 0.058 13.4 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Translin family CRAL_TRIO PF00650.20 EEQ31919.1 - 8.1e-36 123.1 0.0 1.4e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EEQ31919.1 - 0.013 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF1769 PF08588.10 EEQ31919.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Ank_4 PF13637.6 EEQ31921.1 - 4.4e-44 148.3 0.7 3.1e-08 34.0 0.0 8.8 8 1 2 10 10 10 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ31921.1 - 3.2e-43 146.2 3.6 2.9e-10 40.6 0.2 7.7 4 3 5 9 9 9 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ31921.1 - 3.3e-42 142.0 7.6 2.9e-07 30.6 0.1 9.1 8 2 3 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 EEQ31921.1 - 1.8e-37 126.2 14.3 2e-06 28.0 0.0 12.5 13 0 0 13 13 13 8 Ankyrin repeat Ank_3 PF13606.6 EEQ31921.1 - 3.1e-36 119.3 6.4 3e-06 27.2 0.0 12.2 14 0 0 14 14 14 7 Ankyrin repeat Clathrin-link PF09268.10 EEQ31921.1 - 0.0018 17.6 0.2 0.0032 16.8 0.2 1.4 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Glyco_hydro_18 PF00704.28 EEQ31922.1 - 3.9e-55 187.8 1.1 5.2e-55 187.4 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EEQ31922.1 - 1.2e-10 41.7 29.4 1.1e-09 38.6 6.2 4.6 4 0 0 4 4 4 2 Chitin recognition protein Glyco_hydro_85 PF03644.13 EEQ31922.1 - 1.1e-06 28.4 0.1 2.2e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 LysM PF01476.20 EEQ31923.1 - 1.3e-12 47.6 0.0 9.7e-05 22.4 0.0 2.9 3 0 0 3 3 3 2 LysM domain LysM PF01476.20 EEQ31924.1 - 3.2e-12 46.3 0.0 0.0077 16.3 0.0 4.1 4 0 0 4 4 4 3 LysM domain UPF0203 PF05254.12 EEQ31924.1 - 0.00057 20.1 3.8 2 8.7 0.1 3.7 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0203) CarbpepA_inh PF02977.15 EEQ31924.1 - 0.099 12.5 3.9 11 5.9 0.0 4.2 4 0 0 4 4 4 0 Carboxypeptidase A inhibitor Como_LCP PF02247.16 EEQ31924.1 - 0.14 10.8 5.4 11 4.5 0.1 3.7 4 0 0 4 4 4 0 Large coat protein DUF1897 PF09005.10 EEQ31924.1 - 0.32 10.5 1.6 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) Acylphosphatase PF00708.18 EEQ31925.1 - 8e-17 61.4 0.0 8.9e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.17 EEQ31926.1 - 1e-99 332.5 0.0 1.2e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase MAD PF05557.13 EEQ31926.1 - 0.15 10.4 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein adh_short_C2 PF13561.6 EEQ31927.1 - 1.7e-49 168.5 0.0 2.2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ31927.1 - 1.5e-45 155.1 0.2 1.8e-45 154.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ31927.1 - 1.1e-06 28.7 0.1 1.5e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EEQ31927.1 - 0.023 14.1 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme MBOAT PF03062.19 EEQ31928.1 - 4e-44 151.4 16.1 5.4e-33 114.8 8.3 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family FA_desaturase PF00487.24 EEQ31929.1 - 2.7e-28 99.5 22.7 4.2e-28 98.9 22.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EEQ31929.1 - 6.2e-09 35.9 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain APH PF01636.23 EEQ31930.1 - 1.7e-05 24.9 0.0 3.6e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family AAA PF00004.29 EEQ31931.1 - 6e-15 55.8 0.0 1e-14 55.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 EEQ31931.1 - 1e-07 32.1 0.5 1.6e-07 31.5 0.5 1.3 1 0 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.12 EEQ31931.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EEQ31931.1 - 0.004 17.7 0.0 0.02 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EEQ31931.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EEQ31931.1 - 0.032 14.0 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EEQ31931.1 - 0.048 13.2 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EEQ31931.1 - 0.18 10.9 0.1 0.51 9.5 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain RNA_pol_Rpb5_C PF01191.19 EEQ31933.1 - 0.016 15.0 0.0 44 4.0 0.0 3.5 1 1 2 3 3 3 0 RNA polymerase Rpb5, C-terminal domain Engrail_1_C_sig PF10525.9 EEQ31933.1 - 0.059 12.6 3.9 38 3.6 0.0 4.1 4 0 0 4 4 4 0 Engrailed homeobox C-terminal signature domain MAPEG PF01124.18 EEQ31933.1 - 0.3 11.0 0.8 16 5.4 0.1 3.5 2 1 1 3 3 3 0 MAPEG family zf-HIT PF04438.16 EEQ31936.1 - 2.8e-10 39.9 7.3 4.3e-10 39.3 7.3 1.3 1 0 0 1 1 1 1 HIT zinc finger Dopey_N PF04118.14 EEQ31937.1 - 7.2e-118 393.2 0.0 2.5e-117 391.4 0.0 2.0 2 0 0 2 2 2 1 Dopey, N-terminal HEAT_EZ PF13513.6 EEQ31937.1 - 0.16 12.6 0.4 2.2 8.9 0.1 3.3 2 0 0 2 2 2 0 HEAT-like repeat Mon1 PF03164.14 EEQ31938.1 - 1.3e-150 502.0 0.0 1.5e-150 501.8 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DEAD PF00270.29 EEQ31939.1 - 2.8e-22 79.3 0.7 4.8e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ31939.1 - 6.7e-20 71.5 4.1 4.2e-17 62.5 0.0 3.3 4 0 0 4 4 4 2 Helicase conserved C-terminal domain RQC PF09382.10 EEQ31939.1 - 6e-15 55.0 0.0 1.3e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 EEQ31939.1 - 4.5e-14 52.9 9.6 4.5e-14 52.9 9.6 2.5 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 EEQ31939.1 - 1.8e-07 31.1 0.0 4.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 EEQ31939.1 - 2.2e-06 27.8 0.0 6.7e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4110 PF13422.6 EEQ31940.1 - 1.9e-32 111.2 0.1 1.9e-32 111.2 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 EEQ31940.1 - 1.8e-26 91.8 13.2 8.9e-11 41.6 0.0 6.7 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EEQ31940.1 - 4.4e-21 74.7 11.9 1.3e-09 38.1 0.1 6.6 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EEQ31940.1 - 1.6e-14 53.6 3.0 0.0018 18.5 0.1 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EEQ31940.1 - 2.6e-12 46.4 4.6 0.012 15.6 0.1 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EEQ31940.1 - 5e-11 42.0 5.0 0.0036 16.8 0.0 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EEQ31940.1 - 1.9e-10 40.3 3.9 0.42 10.7 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Pyridoxal_deC PF00282.19 EEQ31941.1 - 2.4e-28 98.9 0.0 3.3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EEQ31941.1 - 0.028 13.6 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EEQ31941.1 - 0.17 11.1 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_hydro_61 PF03443.14 EEQ31942.1 - 2.6e-05 24.3 0.0 0.00066 19.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4952 PF16310.5 EEQ31943.1 - 0.077 13.3 1.0 0.17 12.1 1.0 1.6 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) MIF4G PF02854.19 EEQ31944.1 - 7.2e-53 179.4 0.0 1.1e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EEQ31944.1 - 4e-25 87.8 2.4 1.1e-24 86.3 2.4 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 TB2_DP1_HVA22 PF03134.19 EEQ31945.1 - 6.3e-20 70.9 4.6 1e-19 70.2 4.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family F-box-like PF12937.7 EEQ31946.1 - 1.6e-05 24.7 0.3 3.9e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ31946.1 - 0.0032 17.3 0.5 0.0099 15.7 0.5 1.9 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 EEQ31946.1 - 0.007 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 PRANC domain APH PF01636.23 EEQ31948.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 EEQ31949.1 - 9.5e-14 51.1 52.6 1.4e-08 34.0 17.6 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ31949.1 - 0.0029 16.6 12.7 0.0029 16.6 12.7 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TANGO2 PF05742.12 EEQ31950.1 - 1.4e-60 205.5 0.0 1.7e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 BPL_N PF09825.9 EEQ31951.1 - 1.1e-134 449.3 0.0 5.3e-134 447.0 0.0 1.9 1 1 1 2 2 2 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EEQ31951.1 - 7e-25 87.4 0.0 1.1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EEQ31951.1 - 6.1e-06 26.0 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Mgm101p PF06420.12 EEQ31953.1 - 7.7e-74 246.8 0.8 1.6e-72 242.5 0.8 2.1 1 1 0 1 1 1 1 Mitochondrial genome maintenance MGM101 zf-RING_2 PF13639.6 EEQ31954.1 - 1.1e-11 44.9 2.8 1.8e-11 44.2 2.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EEQ31954.1 - 1.7e-10 40.5 1.6 3e-10 39.7 1.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EEQ31954.1 - 3.9e-08 33.0 2.2 6.8e-08 32.2 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ31954.1 - 8.4e-07 28.8 0.5 1.4e-06 28.1 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ31954.1 - 3.8e-05 23.9 3.7 0.00013 22.1 3.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEQ31954.1 - 0.00012 22.0 4.3 0.00025 21.0 4.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ31954.1 - 0.0013 18.6 0.6 0.0023 17.9 0.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ31954.1 - 0.0072 16.2 5.4 0.11 12.4 5.2 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EEQ31954.1 - 0.022 14.6 0.7 0.035 14.0 0.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EEQ31954.1 - 0.034 14.2 1.0 0.069 13.2 1.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EEQ31954.1 - 0.14 12.3 0.4 0.39 10.9 0.4 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EEQ31954.1 - 0.14 11.8 0.4 0.23 11.1 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pex14_N PF04695.13 EEQ31954.1 - 0.23 12.1 2.8 16 6.1 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Prok-RING_1 PF14446.6 EEQ31954.1 - 0.37 10.8 2.6 0.65 10.0 2.6 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 EEQ31954.1 - 8.8 6.5 6.6 0.54 10.3 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger Phage_lysozyme PF00959.19 EEQ31956.1 - 3.2e-12 46.9 0.0 4.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme Stanniocalcin PF03298.13 EEQ31957.1 - 6.4e-06 25.6 0.4 8.3e-06 25.3 0.4 1.1 1 0 0 1 1 1 1 Stanniocalcin family MS_channel PF00924.18 EEQ31958.1 - 7.2e-19 68.2 0.6 1.8e-18 66.8 0.6 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EEQ31958.1 - 0.095 12.3 0.2 0.28 10.8 0.2 1.9 1 0 0 1 1 1 0 EF hand Aminotran_1_2 PF00155.21 EEQ31960.1 - 1.6e-79 267.7 0.0 1.9e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.9 EEQ31962.1 - 1.2e-09 38.3 0.0 2.5e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus 7TMR-HDED PF07697.11 EEQ31962.1 - 0.00056 20.1 0.1 0.0011 19.1 0.0 1.5 2 0 0 2 2 2 1 7TM-HD extracellular TPR_1 PF00515.28 EEQ31963.1 - 2.8e-14 52.2 4.0 7.8e-07 28.7 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ31963.1 - 1.5e-13 49.7 3.7 7.9e-05 22.5 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.24 EEQ31963.1 - 8.2e-08 32.1 0.1 1.6e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.6 EEQ31963.1 - 5.8e-07 29.7 0.1 0.0026 18.0 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ31963.1 - 2.4e-06 27.2 0.3 0.0011 18.8 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ31963.1 - 6.1e-06 25.8 3.0 0.00047 19.8 0.5 3.8 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 EEQ31963.1 - 2.5e-05 24.2 2.5 0.041 14.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ31963.1 - 6.5e-05 23.3 0.1 13 6.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ31963.1 - 0.00023 21.8 0.6 0.13 12.9 0.2 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ31963.1 - 0.0044 17.2 0.0 3.3 7.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ31963.1 - 0.0056 17.0 0.1 0.36 11.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ31963.1 - 0.17 12.8 1.9 2.7 9.1 0.0 3.3 3 1 1 4 4 3 0 Tetratricopeptide repeat HMA PF00403.26 EEQ31964.1 - 3.7e-12 46.5 0.0 6.8e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EEQ31964.1 - 1.3e-08 35.1 0.0 1.8e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Chordopox_RPO7 PF05864.12 EEQ31964.1 - 0.055 13.7 0.1 6.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Pkinase PF00069.25 EEQ31965.1 - 5.2e-62 209.6 0.0 7.5e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31965.1 - 2.2e-26 92.7 0.0 3.4e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ31965.1 - 0.00014 21.2 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEQ31965.1 - 0.0097 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EEQ31965.1 - 0.02 14.5 0.0 0.02 14.5 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 EEQ31965.1 - 0.038 13.3 0.1 0.069 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ31965.1 - 0.15 12.0 0.1 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family MCM_bind PF09739.9 EEQ31965.1 - 4.4 5.6 6.4 5.8 5.2 6.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AMP-binding PF00501.28 EEQ31968.1 - 4.1e-215 714.2 0.0 5.5e-73 246.0 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EEQ31968.1 - 2.8e-124 415.3 0.0 9.2e-44 149.9 0.0 4.7 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.25 EEQ31968.1 - 3.2e-38 129.9 1.9 2e-11 44.0 0.1 4.7 4 0 0 4 4 4 3 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 EEQ31968.1 - 5.5e-35 120.8 0.0 1.2e-34 119.6 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EEQ31968.1 - 1e-10 41.5 0.0 1.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EEQ31968.1 - 1.8e-07 32.0 0.0 0.072 14.1 0.0 3.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 EEQ31968.1 - 0.0016 17.5 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Transferase PF02458.15 EEQ31968.1 - 0.04 12.6 0.0 0.15 10.7 0.0 1.8 2 0 0 2 2 2 0 Transferase family AvrM_N PF18247.1 EEQ31968.1 - 0.16 12.0 1.1 17 5.5 0.0 3.3 3 0 0 3 3 3 0 Flax-rust effector AvrM N-terminal domain eIF-5a PF01287.20 EEQ31968.1 - 0.18 11.9 0.1 66 3.7 0.0 3.4 4 0 0 4 4 4 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Usp PF00582.26 EEQ31969.1 - 5.3e-23 82.1 2.4 9.6e-23 81.3 0.1 2.3 2 0 0 2 2 2 1 Universal stress protein family SpoIIIAH PF12685.7 EEQ31971.1 - 0.017 14.9 0.3 0.02 14.8 0.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF3357 PF11837.8 EEQ31971.1 - 0.077 13.5 0.2 0.19 12.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Apt1 PF10351.9 EEQ31971.1 - 6.5 5.5 6.5 8.6 5.1 6.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SNF2_N PF00176.23 EEQ31972.1 - 3.7e-65 219.9 0.0 6e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ31972.1 - 1.1e-17 64.3 0.0 2.8e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ31972.1 - 6.5e-06 26.2 0.0 2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIF_beta PF02270.15 EEQ31972.1 - 0.0011 19.1 0.1 0.015 15.5 0.0 2.6 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain SPEG_u2 PF16650.5 EEQ31972.1 - 0.0068 16.6 0.6 0.019 15.1 0.6 1.8 1 0 0 1 1 1 1 Unstructured region on SPEG complex protein Pkinase PF00069.25 EEQ31973.1 - 9.3e-26 90.8 3.7 1.6e-22 80.1 0.6 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31973.1 - 5.2e-13 48.9 1.0 5.2e-13 48.9 1.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EEQ31973.1 - 0.011 15.7 0.1 0.011 15.7 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EEQ31973.1 - 0.013 14.5 0.1 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EEQ31973.1 - 0.015 14.9 0.2 0.042 13.5 0.2 1.7 1 1 0 1 1 1 0 RIO1 family eIF-3c_N PF05470.12 EEQ31974.1 - 3.8e-146 487.8 46.2 8.4e-67 225.8 0.2 4.1 1 1 2 4 4 4 3 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EEQ31974.1 - 1.6e-11 44.6 6.3 2.3e-11 44.1 0.2 3.8 3 2 2 5 5 5 1 PCI domain DASH_Ask1 PF08655.10 EEQ31974.1 - 0.29 11.0 1.2 3.2 7.7 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Ask1 CDC45 PF02724.14 EEQ31974.1 - 2 6.6 18.2 3.3 5.9 18.2 1.2 1 0 0 1 1 1 0 CDC45-like protein EAP30 PF04157.16 EEQ31975.1 - 1.4e-72 243.8 0.0 1.6e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_L30_N PF08079.12 EEQ31976.1 - 9.8e-27 93.0 14.9 1.7e-26 92.2 14.9 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EEQ31976.1 - 2.1e-17 62.7 1.7 2.1e-17 62.7 1.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_B PF00136.21 EEQ31977.1 - 6.2e-117 391.1 1.9 6.2e-117 391.1 1.9 1.7 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EEQ31977.1 - 6.6e-68 228.1 1.8 8.5e-68 227.7 0.6 1.9 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EEQ31977.1 - 8.6e-45 153.3 0.0 1.8e-44 152.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EEQ31977.1 - 4.5e-25 87.5 9.8 4.5e-25 87.5 9.8 3.2 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EEQ31977.1 - 0.00028 19.9 0.1 0.00063 18.7 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Endopep_inhib PF16800.5 EEQ31977.1 - 0.035 14.1 0.1 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor PPR_2 PF13041.6 EEQ31979.1 - 8.9e-17 61.0 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 EEQ31979.1 - 2.3e-06 27.5 0.3 6.1e-05 23.0 0.3 2.4 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 EEQ31979.1 - 9.4e-06 25.6 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 EEQ31979.1 - 3e-05 23.6 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 2 PPR repeat Terminase_6C PF17289.2 EEQ31979.1 - 0.096 12.8 0.4 0.14 12.2 0.4 1.3 1 0 0 1 1 1 0 Terminase RNaseH-like domain TPR_14 PF13428.6 EEQ31979.1 - 0.11 13.3 0.1 3.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.29 EEQ31981.1 - 2.5e-50 170.7 0.0 7.7e-49 165.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ31981.1 - 1.5e-29 102.6 0.0 5.8e-29 100.7 0.0 2.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ31981.1 - 0.00011 22.3 0.0 0.0004 20.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEQ31981.1 - 0.01 16.2 0.0 2.7 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.6 EEQ31981.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DUF5335 PF17269.2 EEQ31981.1 - 0.02 14.7 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5335) CMS1 PF14617.6 EEQ31981.1 - 0.059 12.7 0.8 1.4 8.2 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF2443 PF10398.9 EEQ31981.1 - 0.082 13.0 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) UTP25 PF06862.12 EEQ31981.1 - 0.095 11.5 0.0 6.9 5.3 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 EEQ31981.1 - 0.32 11.3 2.2 25 5.1 0.0 3.4 3 1 0 4 4 4 0 AAA domain Phos_pyr_kin PF08543.12 EEQ31982.1 - 2.6e-71 239.9 0.7 4.1e-71 239.2 0.7 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EEQ31982.1 - 2.8e-41 141.6 1.1 1.3e-29 103.6 0.1 2.4 1 1 1 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.24 EEQ31982.1 - 1.4e-06 27.8 0.2 2.5e-05 23.7 0.2 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 EEQ31982.1 - 0.0023 17.4 1.6 0.0049 16.4 0.3 1.9 2 0 0 2 2 2 1 Carbohydrate kinase HK PF02110.15 EEQ31982.1 - 0.0066 15.9 0.9 0.034 13.5 0.1 2.1 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family APH PF01636.23 EEQ31987.1 - 1.2e-12 48.3 0.0 2.7e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ31987.1 - 5.3e-06 26.2 0.0 1.2e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EEQ31987.1 - 0.0043 16.0 0.0 1.9 7.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1679) Kdo PF06293.14 EEQ31987.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEQ31987.1 - 0.082 12.3 0.0 2.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ31987.1 - 0.19 11.0 0.1 1.6 8.0 0.1 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Sds3 PF08598.11 EEQ31988.1 - 9.1e-48 163.1 3.9 1.8e-45 155.6 3.9 2.1 1 1 0 1 1 1 1 Sds3-like DUF908 PF06012.12 EEQ31988.1 - 0.037 13.5 1.7 0.062 12.7 1.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CFEM PF05730.11 EEQ31991.1 - 0.00011 22.3 4.2 0.00011 22.3 4.2 2.1 2 0 0 2 2 2 1 CFEM domain APH PF01636.23 EEQ31992.1 - 1e-09 38.7 0.1 1.4e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ31992.1 - 1.7e-05 24.5 0.0 2.8e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1590 PF07629.11 EEQ31992.1 - 0.0011 18.8 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1590) Pkinase PF00069.25 EEQ31992.1 - 0.12 11.8 0.0 8.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Baculo_PEP_C PF04513.12 EEQ31994.1 - 0.0073 16.3 1.9 0.014 15.5 0.7 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus PilO PF04350.13 EEQ31994.1 - 0.011 15.9 3.3 0.014 15.6 0.2 2.2 1 1 1 2 2 2 0 Pilus assembly protein, PilO TBCA PF02970.16 EEQ31994.1 - 0.033 14.5 3.7 0.042 14.2 1.1 2.5 1 1 1 2 2 2 0 Tubulin binding cofactor A Nbl1_Borealin_N PF10444.9 EEQ31994.1 - 0.11 12.1 0.0 1.9 8.2 0.0 2.3 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal YlbD_coat PF14071.6 EEQ31994.1 - 0.25 11.6 6.6 0.91 9.8 6.4 2.0 1 1 0 1 1 1 0 Putative coat protein DUF2752 PF10825.8 EEQ31994.1 - 0.3 11.2 1.1 0.48 10.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Sterol_MT_C PF08498.10 EEQ31996.1 - 2.7e-23 82.0 0.3 4.7e-23 81.3 0.3 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EEQ31996.1 - 6.4e-19 68.4 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ31996.1 - 1.3e-17 64.2 0.0 2.8e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ31996.1 - 1.6e-17 63.7 0.0 2.2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EEQ31996.1 - 2.2e-12 46.9 0.0 2.8e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EEQ31996.1 - 4.1e-11 43.0 0.0 6.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ31996.1 - 4.4e-11 43.4 0.0 9.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ31996.1 - 4.8e-11 42.4 0.0 9.8e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EEQ31996.1 - 0.00034 20.4 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EEQ31996.1 - 0.0093 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EEQ31996.1 - 0.0097 15.5 0.0 0.022 14.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EEQ31996.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EEQ31996.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase BTB PF00651.31 EEQ31997.1 - 2.5e-06 27.7 0.0 1.1e-05 25.6 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain Peptidase_S24 PF00717.23 EEQ31998.1 - 3.9e-08 33.1 0.0 6.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like NUDE_C PF04880.13 EEQ32000.1 - 0.014 15.9 3.1 0.016 15.7 3.1 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region UQ_con PF00179.26 EEQ32001.1 - 4.7e-43 146.2 0.0 5.3e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ32001.1 - 2e-06 27.6 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EEQ32001.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 EEQ32001.1 - 0.022 15.0 0.1 0.029 14.7 0.1 1.6 1 1 0 1 1 1 0 RWD domain Acyl_transf_3 PF01757.22 EEQ32002.1 - 6.7e-15 55.0 26.3 1.2e-14 54.1 25.8 1.8 1 1 1 2 2 2 1 Acyltransferase family RabGAP-TBC PF00566.18 EEQ32004.1 - 3.7e-34 118.3 1.4 3.4e-33 115.1 0.2 2.9 2 1 0 2 2 2 1 Rab-GTPase-TBC domain LPD23 PF18838.1 EEQ32005.1 - 0.15 11.9 0.1 0.37 10.6 0.1 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 BCS1_N PF08740.11 EEQ32006.1 - 9.3e-49 166.0 0.4 1.4e-48 165.4 0.4 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EEQ32006.1 - 1.2e-18 67.8 0.0 2.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ32006.1 - 8.9e-06 26.2 0.0 2.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EEQ32006.1 - 0.00026 20.2 0.0 0.00052 19.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EEQ32006.1 - 0.0061 16.7 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EEQ32006.1 - 0.012 15.1 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EEQ32006.1 - 0.013 15.5 0.0 0.046 13.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ32006.1 - 0.019 15.3 0.0 0.086 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EEQ32006.1 - 0.019 14.7 0.0 0.06 13.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 EEQ32006.1 - 0.03 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEQ32006.1 - 0.035 14.5 0.0 0.11 12.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.27 EEQ32006.1 - 0.039 14.5 0.0 0.08 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EEQ32006.1 - 0.04 13.6 0.0 0.32 10.7 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ32006.1 - 0.052 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EEQ32006.1 - 0.093 12.1 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.23 EEQ32006.1 - 0.11 12.6 0.0 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ32006.1 - 0.16 11.9 0.0 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Myosin_TH1 PF06017.13 EEQ32006.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Methyltransf_25 PF13649.6 EEQ32008.1 - 1.4e-08 35.3 0.0 3.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ32008.1 - 9.6e-05 23.1 0.0 0.00016 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ32008.1 - 0.006 16.4 0.0 0.17 11.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ32008.1 - 0.0061 16.4 0.0 0.013 15.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain RRM_5 PF13893.6 EEQ32008.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.24 EEQ32009.1 - 9.2e-173 575.4 1.2 1e-172 575.2 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.12 EEQ32010.1 - 2e-40 137.7 10.9 2.7e-40 137.3 10.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 EEQ32010.1 - 0.0011 18.2 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Lyase, catalytic PPL5 PF18168.1 EEQ32010.1 - 0.02 14.2 1.9 0.026 13.8 1.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Rrn6 PF10214.9 EEQ32010.1 - 0.41 9.1 3.1 0.4 9.1 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S49_N PF08496.10 EEQ32010.1 - 0.97 9.5 4.2 1.5 8.9 4.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ERK-JNK_inhib PF15002.6 EEQ32010.1 - 2.2 7.9 12.0 3.2 7.4 12.0 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor NARP1 PF12569.8 EEQ32010.1 - 5.1 5.9 9.4 6.7 5.5 9.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Nucleo_P87 PF07267.11 EEQ32010.1 - 5.7 5.7 6.4 6.3 5.5 6.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 EEQ32010.1 - 5.9 5.1 9.4 7.6 4.7 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-PARP PF00645.18 EEQ32011.1 - 2e-22 79.9 0.6 2e-22 79.9 0.6 3.5 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Kinesin PF00225.23 EEQ32012.1 - 5.4e-56 189.9 0.0 1.2e-55 188.8 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ32012.1 - 6.9e-13 48.8 0.1 8.3e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding bZIP_2 PF07716.15 EEQ32012.1 - 0.0036 17.4 1.7 0.017 15.2 1.7 2.2 1 0 0 1 1 1 1 Basic region leucine zipper AAA_13 PF13166.6 EEQ32012.1 - 0.025 13.3 3.0 0.037 12.7 3.0 1.2 1 0 0 1 1 1 0 AAA domain KLRAQ PF10205.9 EEQ32012.1 - 1.2 9.4 6.9 6.5 7.1 1.2 2.8 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein TPR_11 PF13414.6 EEQ32013.1 - 0.17 11.6 1.2 0.47 10.2 1.2 1.8 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.6 EEQ32013.1 - 0.27 12.2 5.0 2.7 9.1 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SDA1 PF05285.12 EEQ32013.1 - 0.71 9.2 47.9 0.0084 15.6 24.2 2.4 2 0 0 2 2 2 0 SDA1 ChAPs PF09295.10 EEQ32014.1 - 3e-153 510.5 0.0 3.9e-153 510.1 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.28 EEQ32014.1 - 0.00014 21.5 0.1 7.9 6.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ32014.1 - 0.00014 21.7 0.1 0.99 9.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ32014.1 - 0.00039 21.0 2.1 0.66 10.9 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ32014.1 - 0.0011 19.4 0.0 2.6 8.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ32014.1 - 0.0062 16.7 0.3 1 9.5 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ32014.1 - 0.015 15.5 0.6 0.35 11.2 0.1 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ32014.1 - 0.099 12.7 0.8 40 4.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ32014.1 - 0.39 11.0 3.1 1.2 9.4 0.2 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Exo5 PF09810.9 EEQ32016.1 - 3.1e-127 425.1 0.0 3.8e-127 424.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EEQ32016.1 - 0.0024 17.8 0.0 0.25 11.2 0.0 2.7 3 0 0 3 3 3 1 PD-(D/E)XK nuclease superfamily DUF3799 PF12684.7 EEQ32016.1 - 0.0094 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 PDDEXK-like domain of unknown function (DUF3799) Mpv17_PMP22 PF04117.12 EEQ32017.1 - 5.4e-14 52.2 0.1 5.4e-14 52.2 0.1 2.1 3 0 0 3 3 3 1 Mpv17 / PMP22 family FAP PF07174.11 EEQ32017.1 - 5.8 6.3 24.4 9.3 5.6 24.4 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Histone PF00125.24 EEQ32018.1 - 2.5e-49 167.0 3.3 2.8e-49 166.8 3.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EEQ32018.1 - 5.3e-06 26.7 0.0 8.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EEQ32018.1 - 6e-05 23.1 0.7 8.5e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EEQ32018.1 - 0.0013 19.4 1.2 0.0015 19.1 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EEQ32018.1 - 0.0077 16.5 0.2 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EEQ32018.1 - 0.025 14.6 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 EEQ32018.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EEQ32019.1 - 6.1e-09 36.0 0.1 7.4e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EEQ32019.1 - 1.9e-05 25.0 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EEQ32019.1 - 7e-05 22.9 0.1 0.0001 22.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EEQ32019.1 - 0.00017 21.8 0.1 0.00036 20.8 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EEQ32019.1 - 0.00021 21.6 0.1 0.00028 21.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EEQ32019.1 - 0.0038 17.3 0.0 0.0045 17.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EEQ32019.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 EEQ32019.1 - 0.052 14.0 0.1 0.098 13.2 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 EEQ32019.1 - 0.1 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Spore_YhcN_YlaJ PF09580.10 EEQ32021.1 - 0.31 11.1 2.7 1.3 9.0 0.3 2.0 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) zf-C2H2 PF00096.26 EEQ32022.1 - 1.6e-06 28.3 25.1 0.00017 21.9 1.4 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ32022.1 - 2.3e-06 27.9 11.2 0.032 15.1 1.1 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 EEQ32022.1 - 0.84 10.0 6.8 1 9.7 1.5 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Glyco_transf_22 PF03901.17 EEQ32023.1 - 1.1e-87 295.0 19.9 1.3e-87 294.8 19.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HET PF06985.11 EEQ32024.1 - 1.6e-23 83.6 0.0 3.2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gar1 PF04410.14 EEQ32025.1 - 8.3e-37 126.3 0.2 8.3e-37 126.3 0.2 1.9 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region YL1 PF05764.13 EEQ32025.1 - 0.0027 17.9 12.1 0.012 15.7 4.9 2.5 2 0 0 2 2 2 2 YL1 nuclear protein EPSP_synthase PF00275.20 EEQ32026.1 - 5.7e-131 437.0 0.0 8.5e-131 436.5 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EEQ32026.1 - 1.8e-99 332.1 0.0 3.8e-99 331.1 0.0 1.6 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EEQ32026.1 - 7.8e-59 199.7 0.0 1.8e-58 198.5 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EEQ32026.1 - 8.8e-38 129.9 0.0 1.9e-37 128.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 EEQ32026.1 - 4.8e-24 84.4 0.0 1.3e-23 83.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EEQ32026.1 - 1.2e-07 31.4 1.5 2.5e-07 30.3 0.4 2.2 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 EEQ32026.1 - 1.1e-06 28.5 0.0 3.3e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EEQ32026.1 - 2.8e-05 24.2 0.0 7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_24 PF13479.6 EEQ32026.1 - 0.0064 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fe-ADH PF00465.19 EEQ32026.1 - 0.0097 14.8 2.2 0.053 12.3 2.2 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase TPR_1 PF00515.28 EEQ32026.1 - 0.25 11.2 0.6 32 4.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat XRN_M PF17846.1 EEQ32027.1 - 5e-152 506.9 0.2 5e-152 506.9 0.2 1.8 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 EEQ32027.1 - 1.6e-93 312.6 0.4 2.7e-92 308.6 0.0 2.5 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Uso1_p115_head PF04869.14 EEQ32028.1 - 3.1e-110 368.2 0.0 9.6e-110 366.6 0.0 1.9 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EEQ32028.1 - 9.6e-17 61.5 32.3 9.6e-17 61.5 32.3 3.5 1 1 2 3 3 3 2 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 EEQ32028.1 - 0.0044 16.0 52.6 0.016 14.1 7.8 3.2 1 1 2 3 3 3 2 Spc7 kinetochore protein Filament PF00038.21 EEQ32028.1 - 0.21 11.1 49.4 0.77 9.3 49.3 2.0 1 1 0 1 1 1 0 Intermediate filament protein MAD PF05557.13 EEQ32028.1 - 0.23 9.8 47.6 0.38 9.1 47.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein TFIIA PF03153.13 EEQ32028.1 - 0.28 11.2 22.6 0.42 10.6 22.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3584 PF12128.8 EEQ32028.1 - 2.3 5.6 48.6 3.5 5.0 48.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ZnuA PF01297.17 EEQ32028.1 - 2.5 7.4 12.3 74 2.6 11.1 2.6 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic tRNA-synt_1 PF00133.22 EEQ32029.1 - 3.4e-210 699.4 0.0 1.6e-115 386.7 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EEQ32029.1 - 9.2e-24 84.1 0.0 2.5e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EEQ32029.1 - 1.3e-13 50.5 0.0 5.2e-06 25.5 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EEQ32029.1 - 0.054 12.8 0.0 0.82 8.9 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain gp45-slide_C PF09116.10 EEQ32029.1 - 0.073 13.1 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal NDUF_B7 PF05676.13 EEQ32030.1 - 0.00086 19.0 1.3 0.72 9.6 0.2 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 EEQ32030.1 - 0.0019 18.1 0.6 0.0029 17.6 0.6 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EEQ32030.1 - 0.033 14.3 2.7 0.29 11.3 2.3 2.0 1 1 1 2 2 2 0 CHCH domain p450 PF00067.22 EEQ32031.1 - 2.9e-74 250.5 0.0 4.5e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EEQ32031.1 - 1.1e-28 100.3 0.0 1.9e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EEQ32031.1 - 2.5e-21 76.4 0.0 5.3e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EEQ32031.1 - 2.6e-12 47.3 0.0 6.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EEQ32031.1 - 0.0011 19.3 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Sfi1 PF08457.10 EEQ32032.1 - 3.1e-191 636.8 87.6 1.4e-189 631.4 76.1 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein Elongin_A PF06881.11 EEQ32033.1 - 4.3e-28 97.9 1.2 7.3e-28 97.2 1.2 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.7 EEQ32034.1 - 0.011 15.6 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EEQ32034.1 - 0.062 13.2 0.1 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 F-box domain C5HCH PF17982.1 EEQ32034.1 - 3.2 8.0 10.3 0.16 12.2 4.1 2.0 2 0 0 2 2 2 0 NSD Cys-His rich domain Sugar_tr PF00083.24 EEQ32036.1 - 3.9e-76 256.8 19.2 6.9e-75 252.6 19.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ32036.1 - 6.2e-10 38.5 30.3 0.0003 19.8 15.6 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily EBP PF05241.12 EEQ32036.1 - 0.7 9.3 9.8 0.33 10.4 3.0 2.4 2 0 0 2 2 2 0 Emopamil binding protein Band_7 PF01145.25 EEQ32037.1 - 1.3e-15 57.9 0.1 1.3e-15 57.9 0.1 2.5 2 2 1 3 3 3 1 SPFH domain / Band 7 family LCM PF04072.14 EEQ32038.1 - 0.036 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase EphA2_TM PF14575.6 EEQ32038.1 - 0.13 13.1 0.7 49 4.9 0.0 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.13 EEQ32038.1 - 2.2 8.2 11.5 3.3 7.6 11.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 EEQ32038.1 - 2.7 8.1 15.1 0.14 12.2 4.4 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TBCA PF02970.16 EEQ32039.1 - 1.7e-24 86.0 9.5 2e-24 85.7 9.5 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A HAUS5 PF14817.6 EEQ32039.1 - 0.053 12.3 8.5 0.06 12.1 8.5 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF2570 PF10828.8 EEQ32039.1 - 0.14 12.0 5.4 0.18 11.7 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) HSP70 PF00012.20 EEQ32039.1 - 0.24 9.5 7.9 0.28 9.3 7.9 1.0 1 0 0 1 1 1 0 Hsp70 protein Tho2 PF11262.8 EEQ32039.1 - 0.71 9.0 6.7 0.83 8.8 6.7 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMF_DNA_bd PF12329.8 EEQ32039.1 - 0.73 9.9 15.3 1.1 9.3 3.5 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding AAA_23 PF13476.6 EEQ32039.1 - 1.7 9.1 9.4 1.9 9.0 9.4 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 EEQ32039.1 - 2.9 5.7 5.4 3.1 5.6 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RIC3 PF15361.6 EEQ32039.1 - 9.9 6.6 8.7 11 6.4 8.5 1.3 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 THOC7 PF05615.13 EEQ32040.1 - 8.1e-46 155.6 7.7 8.1e-46 155.6 7.7 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 CCDC92 PF14916.6 EEQ32040.1 - 0.0027 17.4 0.2 0.0068 16.1 0.2 1.6 1 0 0 1 1 1 1 Coiled-coil domain of unknown function DUF1843 PF08898.10 EEQ32040.1 - 0.0038 17.7 2.1 0.031 14.8 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) Peroxin-13_N PF04088.13 EEQ32040.1 - 0.021 15.1 0.4 0.061 13.6 0.3 1.8 1 1 1 2 2 2 0 Peroxin 13, N-terminal region Mod_r PF07200.13 EEQ32040.1 - 0.029 14.5 13.3 0.062 13.4 13.2 1.6 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FUSC PF04632.12 EEQ32040.1 - 0.16 10.4 6.4 0.23 10.0 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LMBR1 PF04791.16 EEQ32040.1 - 0.21 10.5 3.6 0.24 10.3 3.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Fer4_NifH PF00142.18 EEQ32040.1 - 0.29 10.5 0.4 0.42 10.0 0.4 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family WXG100 PF06013.12 EEQ32040.1 - 0.39 11.0 5.1 2.6 8.3 0.9 2.8 1 1 1 2 2 2 0 Proteins of 100 residues with WXG TMPIT PF07851.13 EEQ32040.1 - 1.7 7.8 3.8 2.3 7.4 3.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein PTR2 PF00854.21 EEQ32041.1 - 7.7e-99 331.2 8.8 7.7e-99 331.2 8.8 1.6 2 1 0 2 2 2 1 POT family CCB1 PF12046.8 EEQ32041.1 - 0.059 12.7 0.3 0.28 10.5 0.1 2.1 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Malic_M PF03949.15 EEQ32042.1 - 1.1e-92 310.0 0.0 1.5e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EEQ32042.1 - 3.7e-62 209.4 0.0 6.4e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Kinesin PF00225.23 EEQ32044.1 - 5.9e-48 163.5 0.1 5e-33 114.4 0.1 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EEQ32044.1 - 3.9e-06 26.9 0.0 8.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF4449 PF14613.6 EEQ32045.1 - 0.00032 20.9 0.1 0.00032 20.9 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Pex19 PF04614.12 EEQ32045.1 - 0.5 10.1 6.5 0.64 9.7 0.1 2.5 2 1 0 2 2 2 0 Pex19 protein family Ku_PK_bind PF08785.11 EEQ32045.1 - 0.5 10.5 5.0 1 9.5 0.2 3.6 5 0 0 5 5 5 0 Ku C terminal domain like DnaJ PF00226.31 EEQ32046.1 - 1.8e-23 82.4 2.5 2.7e-23 81.8 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EEQ32046.1 - 3.2e-23 82.4 0.0 4.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EEQ32046.1 - 4.1e-13 49.5 16.5 6.7e-13 48.8 16.5 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EEQ32046.1 - 0.0015 18.5 8.3 0.17 11.9 1.3 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EEQ32046.1 - 0.019 14.9 6.6 0.84 9.7 1.1 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SKG6 PF08693.10 EEQ32048.1 - 0.0067 15.8 0.4 0.013 14.9 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 EEQ32048.1 - 0.04 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Amnionless MtrF PF09472.10 EEQ32048.1 - 0.67 9.4 3.0 1.3 8.4 3.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) ADH_N PF08240.12 EEQ32050.1 - 0.0037 17.1 0.2 0.0081 16.0 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_S4 PF00163.19 EEQ32051.1 - 1.1e-10 42.2 3.0 1.3e-10 42.0 2.2 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EEQ32051.1 - 1.7e-10 40.4 0.1 2.8e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 S4 domain PilP PF04351.13 EEQ32051.1 - 0.019 14.9 0.0 0.035 14.1 0.0 1.6 2 0 0 2 2 2 0 Pilus assembly protein, PilP Speriolin_C PF15059.6 EEQ32051.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Speriolin C-terminus MFS_1 PF07690.16 EEQ32054.1 - 2.7e-27 95.6 28.7 2.7e-27 95.6 28.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2681 PF10883.8 EEQ32054.1 - 5.5 7.5 8.4 1.2 9.6 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Glyco_hydro_16 PF00722.21 EEQ32055.1 - 3e-42 144.1 0.6 4.9e-42 143.4 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.6 EEQ32055.1 - 0.0008 19.6 1.0 0.0019 18.3 1.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily tRNA-synt_1b PF00579.25 EEQ32058.1 - 3.3e-65 220.3 0.0 4e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PP2C PF00481.21 EEQ32059.1 - 2.2e-52 178.3 0.0 3.3e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EEQ32059.1 - 1.1e-40 137.2 64.5 1.4e-11 44.0 7.7 10.9 7 3 6 13 13 13 10 Leucine rich repeat LRR_4 PF12799.7 EEQ32059.1 - 3.1e-36 122.8 68.8 3.1e-06 27.4 2.3 11.9 7 2 3 12 12 12 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EEQ32059.1 - 1.9e-21 76.5 0.0 1.6e-20 73.5 0.0 2.3 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 EEQ32059.1 - 3.7e-09 36.3 16.2 0.0041 16.6 1.1 4.7 2 1 1 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EEQ32059.1 - 3.9e-08 32.8 60.6 2.1 9.2 0.1 15.6 15 3 1 16 16 16 4 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.11 EEQ32059.1 - 1.2e-07 31.4 0.1 1.2e-07 31.4 0.1 2.3 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_5 PF13306.6 EEQ32059.1 - 1.1e-05 25.4 3.3 0.14 12.1 0.1 3.9 3 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EEQ32059.1 - 0.0016 18.3 46.6 4.4 7.6 0.3 13.2 15 0 0 15 15 15 3 Leucine Rich repeat MSC PF09402.10 EEQ32060.1 - 3.1e-88 296.5 0.0 5.6e-79 266.0 0.0 2.2 1 1 1 2 2 2 2 Man1-Src1p-C-terminal domain HeH PF12949.7 EEQ32060.1 - 2.8e-16 58.9 0.2 5.1e-16 58.1 0.2 1.5 1 0 0 1 1 1 1 HeH/LEM domain DUF3632 PF12311.8 EEQ32061.1 - 8.1e-18 65.5 0.0 1.1e-14 55.2 0.1 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3632) Pns11_12 PF17464.2 EEQ32061.1 - 0.13 12.0 3.8 0.23 11.1 3.8 1.4 1 0 0 1 1 1 0 Non-structural protein 11 and 12 UCH_1 PF13423.6 EEQ32062.1 - 1e-95 321.0 0.8 1.4e-95 320.6 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EEQ32062.1 - 9.7e-14 52.2 0.0 1.3e-12 48.6 0.0 2.6 3 0 0 3 3 3 1 Exonuclease UCH PF00443.29 EEQ32062.1 - 0.0078 15.7 0.0 0.03 13.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase APH PF01636.23 EEQ32064.1 - 1e-10 41.9 0.0 6.8e-10 39.3 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ32064.1 - 0.01 15.4 0.0 0.032 13.8 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIP PF00161.19 EEQ32064.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosome inactivating protein KH_1 PF00013.29 EEQ32065.1 - 1.5e-94 309.8 13.3 1.1e-12 47.6 0.0 13.7 13 2 0 13 13 13 9 KH domain KH_2 PF07650.17 EEQ32065.1 - 3.7e-09 36.3 19.5 0.0033 17.2 0.4 8.0 7 1 1 8 8 8 3 KH domain SLS PF14611.6 EEQ32065.1 - 1.8e-07 31.3 0.6 0.13 12.1 0.0 6.3 4 2 3 7 7 7 1 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 EEQ32065.1 - 0.01 15.7 7.8 47 3.9 0.0 6.1 8 0 0 8 8 8 0 KH domain BMC PF00936.19 EEQ32065.1 - 0.051 13.6 2.7 0.22 11.5 0.1 3.3 4 0 0 4 4 4 0 BMC domain DMSP_lyase PF16867.5 EEQ32065.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase PHA_gran_rgn PF09650.10 EEQ32065.1 - 2 8.8 6.0 17 5.7 0.0 4.2 4 1 1 5 5 5 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Pkinase PF00069.25 EEQ32066.1 - 1.1e-65 221.6 0.0 1.8e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32066.1 - 1.5e-41 142.4 0.0 2.5e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EEQ32066.1 - 2e-21 76.1 0.2 4.9e-21 74.8 0.2 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EEQ32066.1 - 1.2e-05 24.3 0.1 3.1e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEQ32066.1 - 3.5e-05 23.2 0.0 5.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ32066.1 - 0.022 14.1 1.0 0.031 13.6 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ32066.1 - 0.07 13.0 0.1 0.63 9.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EEQ32066.1 - 0.074 12.1 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 VHS PF00790.19 EEQ32067.1 - 4.5e-32 110.8 1.0 8.1e-32 110.0 1.0 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EEQ32067.1 - 9.5e-18 63.5 0.1 7.1e-17 60.7 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEQ32067.1 - 2.6e-15 56.0 0.1 5.8e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ32067.1 - 3.5e-13 49.0 0.1 1e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 EEQ32067.1 - 1.2e-10 41.5 1.5 4.6e-10 39.7 1.5 2.0 1 0 0 1 1 1 1 GAT domain DUF4598 PF15370.6 EEQ32067.1 - 0.0049 17.3 0.1 0.013 16.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) UIM PF02809.20 EEQ32067.1 - 0.02 14.8 1.4 0.05 13.5 1.4 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif K_trans PF02705.16 EEQ32068.1 - 4.7e-185 616.1 21.2 5.5e-185 615.9 21.2 1.0 1 0 0 1 1 1 1 K+ potassium transporter Cyt-b5 PF00173.28 EEQ32069.1 - 9.1e-24 83.4 0.1 1.2e-23 83.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GTP_EFTU PF00009.27 EEQ32070.1 - 4.4e-47 160.1 0.0 8e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EEQ32070.1 - 4e-19 68.7 6.8 8.1e-19 67.7 6.8 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 EEQ32070.1 - 5.8e-09 36.2 0.0 1.5e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEQ32070.1 - 1.1e-07 32.2 0.1 2.9e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ32070.1 - 4.4e-06 26.8 0.0 0.00011 22.2 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EEQ32070.1 - 0.011 15.3 0.0 0.032 13.7 0.0 1.7 1 1 1 2 2 2 0 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ32070.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EEQ32070.1 - 0.052 13.1 0.1 0.62 9.6 0.1 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B HSP70 PF00012.20 EEQ32071.1 - 1.5e-259 862.3 11.6 1.7e-259 862.1 11.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ32071.1 - 2.5e-18 66.0 1.3 3.5e-17 62.2 0.6 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EEQ32071.1 - 0.0025 16.9 0.4 0.032 13.2 0.3 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EEQ32071.1 - 0.0099 15.2 2.3 0.95 8.7 0.2 2.9 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EEQ32071.1 - 0.017 14.6 0.1 0.74 9.3 0.0 2.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 EEQ32071.1 - 0.081 12.2 1.5 0.88 8.7 0.0 2.5 2 1 0 3 3 3 0 StbA protein FGGY_C PF02782.16 EEQ32071.1 - 0.09 12.5 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EEQ32071.1 - 0.33 11.4 7.7 9.7 6.7 0.2 3.5 3 2 0 3 3 3 0 Cell division protein FtsA FIVAR PF07554.13 EEQ32071.1 - 3.1 8.6 7.2 10 7.0 0.5 3.7 4 0 0 4 4 4 0 FIVAR domain UCH PF00443.29 EEQ32072.1 - 1e-53 182.5 0.1 1.5e-53 182.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ32072.1 - 3.1e-16 59.9 0.7 8.1e-15 55.2 0.7 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EEQ32072.1 - 0.00026 21.5 0.0 0.00068 20.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain TPR_11 PF13414.6 EEQ32072.1 - 0.04 13.6 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 TPR repeat VHS PF00790.19 EEQ32073.1 - 2.2e-42 144.3 3.3 7.7e-42 142.5 0.4 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EEQ32073.1 - 5.1e-16 58.6 1.4 8.9e-16 57.8 1.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EEQ32073.1 - 6.4e-08 32.0 6.2 0.0014 18.4 1.9 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 EEQ32073.1 - 1.3e-05 25.4 0.3 8.4e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 GAT domain Npa1 PF11707.8 EEQ32073.1 - 0.016 14.6 0.2 0.035 13.5 0.2 1.6 1 1 0 1 1 1 0 Ribosome 60S biogenesis N-terminal FYVE_2 PF02318.16 EEQ32073.1 - 0.072 13.3 0.5 0.17 12.1 0.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger PP2C_C PF07830.13 EEQ32073.1 - 0.22 12.0 2.4 3.2 8.3 0.6 3.1 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain OrfB_Zn_ribbon PF07282.11 EEQ32073.1 - 0.68 9.9 3.6 1.6 8.7 3.6 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Fer4_2 PF12797.7 EEQ32073.1 - 3.3 8.0 4.3 2.1 8.6 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain PBP1_TM PF14812.6 EEQ32075.1 - 0.012 16.0 3.7 0.035 14.5 0.9 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TCO89 PF10452.9 EEQ32075.1 - 0.017 14.1 0.1 0.017 14.1 0.1 3.5 2 1 0 2 2 2 0 TORC1 subunit TCO89 RCC1 PF00415.18 EEQ32076.1 - 4.8e-22 78.3 0.1 2e-07 31.5 0.0 5.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EEQ32076.1 - 1.6e-13 50.1 5.8 3.6e-09 36.2 0.2 4.1 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EEQ32076.1 - 1.1e-10 41.8 0.1 1.2e-06 28.7 0.0 2.7 2 1 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 EEQ32076.1 - 1.5e-05 25.5 0.3 0.00013 22.4 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ32076.1 - 0.0013 19.2 0.0 0.0037 17.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEQ32076.1 - 0.0015 18.9 0.1 0.39 11.4 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat ATG13 PF10033.9 EEQ32077.1 - 3.2e-36 125.2 0.0 7.9e-27 94.5 0.2 2.3 1 1 1 2 2 2 2 Autophagy-related protein 13 adh_short PF00106.25 EEQ32080.1 - 3.4e-24 85.4 0.0 3.1e-23 82.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ32080.1 - 8.6e-11 41.8 0.0 2.1e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ32080.1 - 2e-10 40.9 0.0 2.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ32080.1 - 6.5e-09 35.6 0.0 8.7e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EEQ32080.1 - 8.1e-05 21.9 0.1 0.00011 21.5 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EEQ32080.1 - 0.002 17.6 0.1 0.0024 17.3 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EEQ32080.1 - 0.019 15.2 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EEQ32080.1 - 0.035 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NUMOD1 PF07453.13 EEQ32080.1 - 0.063 13.6 0.3 0.57 10.5 0.1 2.5 3 0 0 3 3 3 0 NUMOD1 domain DUF2236 PF09995.9 EEQ32082.1 - 2.3e-09 37.8 0.0 4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Methyltransf_25 PF13649.6 EEQ32083.1 - 3.3e-06 27.7 0.0 1.3e-05 25.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain AMP-binding_C PF13193.6 EEQ32083.1 - 7.7e-05 23.6 0.1 0.044 14.8 0.1 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_11 PF08241.12 EEQ32083.1 - 7.9e-05 23.2 0.0 0.00026 21.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ32083.1 - 0.0019 18.0 0.0 0.0077 16.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ32083.1 - 0.0022 17.8 0.0 0.092 12.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ32083.1 - 0.0023 18.6 0.0 0.0066 17.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FMN_red PF03358.15 EEQ32083.1 - 0.014 15.2 0.0 0.069 12.9 0.0 2.1 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Methyltransf_16 PF10294.9 EEQ32083.1 - 0.014 15.1 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Lysine methyltransferase RNAse_A_bac PF18431.1 EEQ32083.1 - 0.098 13.6 0.0 0.33 11.9 0.0 1.9 1 0 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain Nif11 PF07862.11 EEQ32083.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Nif11 domain FA_hydroxylase PF04116.13 EEQ32084.1 - 4e-25 88.7 17.1 4e-25 88.7 17.1 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1993 PF09351.10 EEQ32085.1 - 2.5e-07 31.0 0.0 3.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) MmgE_PrpD PF03972.14 EEQ32085.1 - 0.055 12.0 0.0 0.075 11.6 0.0 1.1 1 0 0 1 1 1 0 MmgE/PrpD family CFC PF09443.10 EEQ32086.1 - 0.65 9.9 5.1 0.26 11.2 2.4 1.7 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Trp_DMAT PF11991.8 EEQ32087.1 - 3.6e-102 342.5 0.0 1.5e-101 340.5 0.0 1.7 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase Condensation PF00668.20 EEQ32088.1 - 1.2e-83 281.3 0.0 1.2e-33 116.5 0.0 3.3 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 EEQ32088.1 - 4e-75 253.0 0.0 7.7e-75 252.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EEQ32088.1 - 2.8e-66 223.7 0.7 5.2e-66 222.8 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EEQ32088.1 - 3e-51 173.9 0.0 8.4e-51 172.4 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EEQ32088.1 - 7.1e-47 160.5 1.6 1.4e-46 159.5 1.6 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EEQ32088.1 - 6.3e-44 150.4 2.0 1e-42 146.4 0.1 2.4 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EEQ32088.1 - 6e-31 106.9 0.0 3.3e-30 104.5 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EEQ32088.1 - 1.4e-25 89.4 0.9 2.4e-11 43.8 0.1 3.2 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EEQ32088.1 - 2.1e-19 70.1 0.0 9.9e-19 67.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EEQ32088.1 - 3.4e-13 49.7 0.0 1.5e-12 47.6 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EEQ32088.1 - 5.7e-11 42.2 0.0 4.4e-10 39.3 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 EEQ32088.1 - 6.3e-11 42.8 0.0 9e-10 39.1 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EEQ32088.1 - 1.6e-10 42.2 0.1 2.7e-09 38.2 0.0 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EEQ32088.1 - 3.5e-10 40.0 0.0 9.2e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ32088.1 - 3.4e-09 37.2 0.0 1.4e-08 35.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EEQ32088.1 - 4.7e-08 33.5 0.1 3.2e-06 27.6 0.0 2.9 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 EEQ32088.1 - 9.3e-07 28.7 0.1 2e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 EEQ32088.1 - 5.3e-06 26.3 0.0 1.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ32088.1 - 6.6e-05 22.4 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 EEQ32088.1 - 0.00022 20.7 0.1 0.00049 19.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 EEQ32088.1 - 0.021 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EEQ32088.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ACP_syn_III PF08545.10 EEQ32088.1 - 0.04 13.8 0.2 0.18 11.7 0.2 2.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AMP-binding_C PF13193.6 EEQ32088.1 - 0.081 13.9 0.0 0.51 11.4 0.0 2.5 2 0 0 2 2 1 0 AMP-binding enzyme C-terminal domain GyrB_insert PF18053.1 EEQ32088.1 - 0.12 12.2 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 1 0 DNA gyrase B subunit insert domain HNH_2 PF13391.6 EEQ32089.1 - 9e-05 22.5 0.0 0.00024 21.2 0.0 1.8 1 1 0 1 1 1 1 HNH endonuclease DUF148 PF02520.17 EEQ32089.1 - 0.12 12.5 0.7 0.5 10.5 0.7 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF148 FAD_binding_4 PF01565.23 EEQ32090.1 - 1.9e-24 86.0 0.2 3.8e-24 85.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EEQ32090.1 - 5.2e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like SET PF00856.28 EEQ32091.1 - 2e-14 54.4 0.1 2.8e-13 50.6 0.1 2.7 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 EEQ32091.1 - 2.7e-05 24.0 2.2 0.053 13.7 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ32091.1 - 9.1e-05 22.7 1.5 0.00026 21.2 1.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ32091.1 - 0.00026 20.9 0.1 0.006 16.7 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ32091.1 - 0.0022 17.7 1.8 0.53 10.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ32091.1 - 0.0026 18.4 3.3 0.24 12.1 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ32091.1 - 0.069 14.0 0.1 0.28 12.1 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4192 PF13830.6 EEQ32091.1 - 0.23 11.5 2.3 13 5.7 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4192) Sulfotransfer_4 PF17784.1 EEQ32092.1 - 8.3e-72 241.5 0.0 1e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EEQ32092.1 - 0.00047 20.6 0.5 0.047 14.1 0.0 2.6 1 1 1 2 2 2 2 Sulfotransferase family NUC153 PF08159.12 EEQ32093.1 - 8.9e-10 38.2 1.3 1.8e-09 37.2 1.3 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EEQ32093.1 - 0.00016 22.4 0.1 12 6.9 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ32093.1 - 0.0062 16.8 0.0 0.037 14.3 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Med13_C PF06333.12 EEQ32096.1 - 5.1e-60 203.5 7.7 1.4e-59 202.0 7.7 1.7 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 EEQ32096.1 - 8.6e-51 173.2 1.7 1.7e-50 172.2 1.7 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 EEQ32096.1 - 2.1e-24 86.7 8.9 8.8e-17 61.7 0.2 4.0 3 1 1 4 4 4 2 MID domain of medPIWI p450 PF00067.22 EEQ32097.1 - 6.1e-66 223.0 0.0 7.8e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 EEQ32097.1 - 0.14 11.9 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) p450 PF00067.22 EEQ32098.1 - 5e-34 117.9 0.0 6.9e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF489 PF04356.12 EEQ32098.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Ribosomal_L33 PF00471.20 EEQ32099.1 - 1.4e-05 25.4 0.0 1.6e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Get5_bdg PF16843.5 EEQ32100.1 - 0.089 12.3 0.4 0.29 10.7 0.1 2.0 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein PikAIV_N PF18605.1 EEQ32100.1 - 1.6 8.4 11.0 1.9 8.1 0.1 5.3 6 0 0 6 6 6 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Shisa PF13908.6 EEQ32102.1 - 0.0011 19.2 0.0 0.0014 18.9 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator FHIPEP PF00771.20 EEQ32102.1 - 0.094 11.2 0.6 0.12 10.8 0.6 1.1 1 0 0 1 1 1 0 FHIPEP family OppC_N PF12911.7 EEQ32102.1 - 0.18 11.8 0.6 0.77 9.8 0.0 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Cellulase PF00150.18 EEQ32103.1 - 5e-08 32.7 4.2 6.1e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Insulin_TMD PF17870.1 EEQ32103.1 - 0.44 10.6 1.7 0.85 9.7 1.7 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 EEQ32103.1 - 1.9 9.4 0.0 1.9 9.4 0.0 3.6 4 1 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 EEQ32104.1 - 1.9e-54 184.8 0.0 2.9e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32104.1 - 1.7e-28 99.6 0.0 2.5e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ32104.1 - 1.2e-05 24.8 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ32104.1 - 6.6e-05 21.9 0.5 0.00056 18.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EEQ32104.1 - 0.012 15.6 2.1 0.019 14.9 0.2 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EEQ32104.1 - 0.029 13.7 0.2 0.047 13.0 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EEQ32104.1 - 0.07 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EEQ32104.1 - 0.28 10.2 0.1 0.41 9.7 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 SNF2_N PF00176.23 EEQ32105.1 - 1.4e-66 224.6 0.1 4e-65 219.8 0.1 2.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ32105.1 - 6.8e-16 58.6 0.1 3.8e-15 56.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ32105.1 - 9.8e-06 25.4 0.0 3.3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EEQ32105.1 - 0.0001 22.3 0.0 0.0013 18.8 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 EEQ32105.1 - 0.023 14.4 0.0 0.072 12.7 0.0 1.8 1 0 0 1 1 1 0 DEAD_2 Auto_anti-p27 PF06677.12 EEQ32105.1 - 0.27 11.4 0.8 0.56 10.4 0.8 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_L34e PF01199.18 EEQ32105.1 - 0.55 10.6 3.1 2.1 8.7 3.1 2.0 1 0 0 1 1 1 0 Ribosomal protein L34e DUF3736 PF12540.8 EEQ32105.1 - 0.74 9.9 4.3 2 8.6 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) PALP PF00291.25 EEQ32107.1 - 3.5e-54 184.2 0.2 4.1e-54 184.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 EEQ32108.1 - 1.4e-21 76.8 57.0 3.3e-20 72.3 46.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EEQ32109.1 - 5.5e-33 114.3 23.9 4.5e-17 62.0 10.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ32109.1 - 8.3e-09 34.5 30.5 0.00088 17.9 9.2 3.2 3 0 0 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 EEQ32109.1 - 2e-05 23.7 19.9 0.0002 20.4 19.9 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EEQ32109.1 - 0.00013 21.0 18.0 0.02 13.7 1.9 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 EEQ32109.1 - 0.11 10.8 14.0 0.0074 14.7 3.0 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF3938 PF13074.6 EEQ32109.1 - 0.24 11.6 4.3 1.1 9.5 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) BT1 PF03092.16 EEQ32109.1 - 0.29 9.3 8.8 0.17 10.1 0.1 3.2 3 1 0 3 3 3 0 BT1 family CoA_binding_3 PF13727.6 EEQ32109.1 - 1.2 9.1 6.9 0.72 9.8 4.3 2.0 2 0 0 2 2 2 0 CoA-binding domain OATP PF03137.20 EEQ32109.1 - 2.2 6.5 15.7 0.075 11.3 0.5 3.2 2 2 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3270 PF11674.8 EEQ32109.1 - 3.7 7.8 5.5 23 5.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) SIR2 PF02146.17 EEQ32110.1 - 1.5e-38 132.4 0.0 1.1e-37 129.6 0.0 1.9 1 1 0 1 1 1 1 Sir2 family PhnA_Zn_Ribbon PF08274.12 EEQ32110.1 - 2.3 8.2 5.2 2.8 8.0 1.3 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Pyridox_ox_2 PF12900.7 EEQ32111.1 - 1.8e-36 125.2 0.0 3.1e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.25 EEQ32112.1 - 8.8e-18 64.6 0.4 1.2e-17 64.2 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32112.1 - 2.9e-16 59.5 0.1 3.9e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ32112.1 - 0.0011 18.3 0.0 0.0025 17.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ32112.1 - 0.0013 18.2 0.1 0.0021 17.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEQ32112.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EEQ32112.1 - 0.069 13.1 0.7 0.16 11.9 0.7 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family ADH_zinc_N PF00107.26 EEQ32114.1 - 4.6e-21 75.1 0.0 8.3e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ32114.1 - 2.4e-11 44.8 0.1 6e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ32114.1 - 4.4e-07 29.7 0.1 1.7e-06 27.9 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FR47 PF08445.10 EEQ32115.1 - 9.1e-09 35.2 0.0 0.00023 21.1 0.0 2.9 2 1 1 3 3 3 2 FR47-like protein Acetyltransf_1 PF00583.25 EEQ32115.1 - 1e-05 25.8 0.0 0.0001 22.5 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EEQ32115.1 - 2.4e-05 25.0 0.0 5.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ32115.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EEQ32115.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_M24 PF00557.24 EEQ32116.1 - 1.5e-41 142.4 0.0 3.7e-41 141.1 0.0 1.7 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EEQ32116.1 - 3.1e-37 127.0 0.0 5.2e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RuBisCO_large PF00016.20 EEQ32116.1 - 0.082 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Dfp1_Him1_M PF08630.10 EEQ32117.1 - 5.8e-36 123.5 0.0 1.5e-35 122.2 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 EEQ32117.1 - 3.5e-20 71.8 1.1 5.6e-20 71.2 1.1 1.3 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 EEQ32117.1 - 0.0021 18.4 0.0 0.0065 16.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EEQ32117.1 - 0.031 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Pantoate_transf PF02548.15 EEQ32118.1 - 3.6e-107 357.6 2.6 4.3e-107 357.3 2.6 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EEQ32118.1 - 1.4e-09 37.8 0.8 1.9e-09 37.3 0.1 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.13 EEQ32119.1 - 2.9e-27 94.9 0.0 4.4e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EEQ32119.1 - 0.047 13.9 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like DUF4267 PF14087.6 EEQ32121.1 - 2.4e-21 75.9 3.1 2.8e-21 75.7 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Pkinase PF00069.25 EEQ32122.1 - 2.5e-07 30.3 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32122.1 - 0.0019 17.5 0.0 0.0047 16.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ32122.1 - 0.014 14.2 0.0 0.039 12.7 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EEQ32122.1 - 0.015 15.2 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EEQ32122.1 - 0.018 14.4 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEQ32122.1 - 0.24 11.0 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pox_P21 PF05313.12 EEQ32123.1 - 0.85 9.2 3.7 2.1 7.9 1.2 2.4 2 0 0 2 2 2 0 Poxvirus P21 membrane protein UQ_con PF00179.26 EEQ32124.1 - 4e-36 123.8 0.1 4.9e-36 123.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.6 EEQ32126.1 - 4.6e-11 43.2 0.6 1.2e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2011 PF09428.10 EEQ32127.1 - 2.2e-30 104.7 0.4 1.3e-29 102.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) D123 PF07065.14 EEQ32129.1 - 0.00017 20.8 0.0 0.0023 17.1 0.0 2.1 1 1 0 1 1 1 1 D123 R2K_2 PF18299.1 EEQ32129.1 - 0.0006 19.7 0.0 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 Sulfotransfer_3 PF13469.6 EEQ32130.1 - 0.02 15.3 0.0 0.52 10.7 0.0 2.3 2 0 0 2 2 2 0 Sulfotransferase family 3Beta_HSD PF01073.19 EEQ32131.1 - 2.4e-48 164.6 0.0 3e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EEQ32131.1 - 3.4e-27 95.5 0.0 4.5e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EEQ32131.1 - 3.9e-14 52.8 0.1 1.7e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EEQ32131.1 - 2.2e-10 40.2 0.2 8.7e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EEQ32131.1 - 6.2e-07 28.8 0.0 8.7e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EEQ32131.1 - 1.9e-05 24.6 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EEQ32131.1 - 0.0036 16.5 0.5 0.041 13.0 0.4 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EEQ32131.1 - 0.0054 16.7 1.4 0.04 13.8 1.4 2.2 1 1 0 1 1 1 1 KR domain PglD_N PF17836.1 EEQ32131.1 - 0.08 13.6 0.2 0.28 11.9 0.2 1.9 1 0 0 1 1 1 0 PglD N-terminal domain HET-S PF17108.5 EEQ32131.1 - 0.27 11.0 3.2 0.47 10.2 0.2 2.3 2 0 0 2 2 2 0 N-terminal small S protein of HET, non-prionic Cerato-platanin PF07249.12 EEQ32132.1 - 2.7e-43 146.9 0.3 3.2e-43 146.6 0.3 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 EEQ32132.1 - 0.0075 16.1 0.1 0.012 15.4 0.1 1.5 1 1 0 1 1 1 1 Barwin family Choline_kinase PF01633.20 EEQ32133.1 - 6.8e-05 22.5 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EEQ32133.1 - 0.0011 19.0 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ32133.1 - 0.048 12.5 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 EEQ32133.1 - 0.12 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase MFS_1 PF07690.16 EEQ32134.1 - 7.1e-47 160.0 45.1 7.1e-47 160.0 45.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ32134.1 - 4e-16 58.9 12.3 4e-16 58.9 12.3 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EEQ32134.1 - 4.6e-08 32.0 22.3 2.5e-07 29.6 22.3 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EEQ32134.1 - 0.0019 17.1 6.7 0.0019 17.1 6.7 3.1 2 2 0 2 2 2 1 MFS_1 like family Flavoprotein PF02441.19 EEQ32135.1 - 2e-12 47.1 0.0 3.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 EEQ32135.1 - 0.0077 16.8 0.4 24 5.6 0.1 4.5 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Peptidase_S8 PF00082.22 EEQ32136.1 - 1.8e-28 99.7 8.0 2.9e-28 99.0 8.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ32136.1 - 9e-11 42.3 0.0 1.7e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 p450 PF00067.22 EEQ32137.1 - 1.6e-64 218.4 0.0 2e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_11 PF13720.6 EEQ32137.1 - 0.072 13.6 0.1 16 6.0 0.0 2.6 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Asparaginase_2 PF01112.18 EEQ32138.1 - 1.7e-52 178.4 0.2 1.5e-50 172.0 0.2 3.5 1 1 0 1 1 1 1 Asparaginase Tim17 PF02466.19 EEQ32139.1 - 7.4e-27 93.9 7.1 9.4e-27 93.6 7.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TraQ PF09679.10 EEQ32140.1 - 0.053 13.4 0.8 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Dsh_C PF12316.8 EEQ32140.1 - 7.9 6.8 19.2 10 6.4 8.5 2.3 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Peptidase_M20 PF01546.28 EEQ32141.1 - 5.6e-21 75.2 0.0 1.5e-19 70.5 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EEQ32141.1 - 7.9e-11 42.3 14.6 0.062 14.2 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.14 EEQ32141.1 - 2.8e-05 24.0 0.0 6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EEQ32141.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 ANAPC4_WD40 PF12894.7 EEQ32141.1 - 0.018 15.4 0.0 5.2 7.4 0.0 4.0 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF747 PF05346.11 EEQ32142.1 - 1.3e-78 264.7 0.5 1.1e-46 159.8 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic membrane protein family DUF4834 PF16118.5 EEQ32142.1 - 0.028 15.4 1.1 0.28 12.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) KCH PF16944.5 EEQ32143.1 - 7.9e-93 310.8 7.5 1.1e-92 310.4 7.5 1.1 1 0 0 1 1 1 1 Fungal potassium channel APH PF01636.23 EEQ32146.1 - 4.4e-21 75.9 0.1 1.4e-20 74.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Peptidase_M43 PF05572.13 EEQ32147.1 - 2e-16 60.3 0.3 3.3e-16 59.5 0.3 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EEQ32147.1 - 1.9e-06 28.4 0.3 1.5e-05 25.5 0.3 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EEQ32147.1 - 1.1e-05 25.7 1.2 2.4e-05 24.6 1.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EEQ32147.1 - 0.0017 18.1 0.9 0.0048 16.6 0.9 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EEQ32147.1 - 0.0053 16.6 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 EEQ32147.1 - 0.039 12.9 0.1 0.061 12.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.24 EEQ32147.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M7 PF02031.16 EEQ32147.1 - 4.5 7.4 7.4 0.3 11.2 1.2 2.1 3 0 0 3 3 3 0 Streptomyces extracellular neutral proteinase (M7) family ERG4_ERG24 PF01222.17 EEQ32148.1 - 2.4e-150 501.1 16.1 2.7e-150 500.9 16.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family FAD_binding_4 PF01565.23 EEQ32149.1 - 4e-18 65.5 0.6 7.5e-18 64.6 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EEQ32149.1 - 0.00023 21.2 0.1 0.00045 20.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DHquinase_I PF01487.15 EEQ32149.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Type I 3-dehydroquinase YqhR PF11085.8 EEQ32150.1 - 0.025 14.5 1.1 0.068 13.1 1.1 1.7 1 0 0 1 1 1 0 Conserved membrane protein YqhR Ank_2 PF12796.7 EEQ32152.1 - 1.7e-60 201.6 9.2 7.4e-17 61.7 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ32152.1 - 5.3e-39 132.1 0.9 2.1e-09 37.7 0.0 6.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ32152.1 - 6.9e-37 121.3 1.1 4.1e-05 23.6 0.0 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 EEQ32152.1 - 9.2e-37 123.9 4.5 6.1e-06 26.5 0.0 8.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EEQ32152.1 - 5.5e-29 99.9 8.9 6.2e-07 29.6 0.0 6.2 4 2 2 7 7 7 6 Ankyrin repeats (many copies) GATase_7 PF13537.6 EEQ32152.1 - 0.00023 21.1 0.0 15 5.5 0.0 4.6 3 2 3 6 6 6 2 Glutamine amidotransferase domain DUF3868 PF12984.7 EEQ32152.1 - 0.01 15.6 0.0 6 6.7 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3868) Pkinase PF00069.25 EEQ32153.1 - 1.8e-06 27.5 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EEQ32153.1 - 0.00024 21.1 0.0 0.00024 21.1 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.6 EEQ32153.1 - 0.0057 16.6 0.0 2.3 8.2 0.0 2.6 1 1 1 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.20 EEQ32153.1 - 0.0077 15.8 0.7 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Atg14 PF10186.9 EEQ32153.1 - 0.27 10.3 10.4 0.49 9.4 10.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PTPRCAP PF15713.5 EEQ32153.1 - 1.3 9.3 16.6 3 8.1 13.5 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 EEQ32153.1 - 2.2 6.3 10.8 2.9 5.9 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase_fungal PF17667.1 EEQ32153.1 - 4.6 5.9 10.8 0.66 8.7 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase DUF3584 PF12128.8 EEQ32153.1 - 9.5 3.6 19.8 13 3.1 19.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CCM2_C PF16545.5 EEQ32154.1 - 0.055 14.0 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology AIF_C PF14721.6 EEQ32154.1 - 1.2 9.5 6.3 2.6 8.4 6.3 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term LMBR1 PF04791.16 EEQ32154.1 - 2.8 6.7 4.9 3.4 6.5 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 EEQ32154.1 - 6.3 6.3 8.8 9.1 5.7 8.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit F-box-like PF12937.7 EEQ32156.1 - 9.4e-08 31.8 0.1 2e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ32156.1 - 0.0045 16.8 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain Fibrinogen_aC PF12160.8 EEQ32156.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha C domain VMA21 PF09446.10 EEQ32157.1 - 2.3e-11 43.6 4.7 3.1e-11 43.2 4.7 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF1772 PF08592.11 EEQ32157.1 - 0.055 13.8 0.0 0.057 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF2406 PF10295.9 EEQ32158.1 - 0.00095 19.8 4.8 0.0017 19.0 0.0 3.3 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.18 EEQ32159.1 - 3e-41 139.5 0.6 3.3e-41 139.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EEQ32159.1 - 0.0013 18.9 0.0 0.89 9.8 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain SRF-TF PF00319.18 EEQ32160.1 - 1.7e-23 81.8 0.3 2.5e-23 81.3 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3602 PF12223.8 EEQ32162.1 - 1.2e-15 57.9 3.8 5e-11 43.1 0.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) CBM_14 PF01607.24 EEQ32164.1 - 3.6e-07 30.2 0.3 5.1e-07 29.8 0.3 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Peptidase_S64 PF08192.11 EEQ32165.1 - 3.8e-05 22.4 0.0 0.00065 18.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S64 Trypsin_2 PF13365.6 EEQ32165.1 - 0.04 14.8 0.0 0.24 12.3 0.0 2.1 1 1 0 1 1 1 0 Trypsin-like peptidase domain COPI_C PF06957.11 EEQ32165.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus COesterase PF00135.28 EEQ32167.1 - 1.1e-94 318.1 0.0 1.3e-94 318.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EEQ32167.1 - 2e-08 34.3 0.1 1.3e-07 31.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold F-actin_cap_A PF01267.17 EEQ32168.1 - 5.9e-89 298.0 0.1 6.2e-86 288.1 0.1 2.0 2 0 0 2 2 2 2 F-actin capping protein alpha subunit FSIP1 PF15554.6 EEQ32170.1 - 0.031 13.4 3.6 0.045 12.9 3.6 1.2 1 0 0 1 1 1 0 FSIP1 family KIAA1328 PF15369.6 EEQ32170.1 - 1.6 8.5 4.2 2.5 7.9 4.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Menin PF05053.13 EEQ32170.1 - 2.5 6.4 11.4 3.5 5.9 11.4 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 EEQ32170.1 - 2.7 6.5 8.2 3.4 6.1 8.2 1.1 1 0 0 1 1 1 0 Macoilin family NST1 PF13945.6 EEQ32170.1 - 2.9 7.9 17.7 6.6 6.8 17.7 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Presenilin PF01080.17 EEQ32170.1 - 7.1 5.3 6.5 10 4.8 6.5 1.2 1 0 0 1 1 1 0 Presenilin PAP2 PF01569.21 EEQ32171.1 - 9.5e-30 103.1 0.4 9.5e-30 103.1 0.4 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EEQ32171.1 - 0.15 11.7 11.1 0.068 12.9 7.0 2.4 1 1 1 2 2 2 0 PAP2 superfamily DUF2418 PF10332.9 EEQ32171.1 - 0.38 11.3 3.8 1.4 9.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) Med7 PF05983.11 EEQ32172.1 - 8.5e-54 182.5 0.4 1e-53 182.3 0.4 1.1 1 0 0 1 1 1 1 MED7 protein TT_ORF2 PF02957.15 EEQ32172.1 - 0.27 12.2 2.3 0.58 11.1 0.7 2.0 2 0 0 2 2 2 0 TT viral ORF2 HEAT PF02985.22 EEQ32174.1 - 8.1e-20 69.2 5.5 1.5e-05 24.8 0.1 9.6 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 EEQ32174.1 - 8.3e-19 67.8 3.8 0.00028 21.2 0.0 7.5 6 1 0 7 7 7 4 HEAT repeats HEAT_EZ PF13513.6 EEQ32174.1 - 2.4e-18 66.2 12.6 6.1e-07 29.8 0.0 10.0 11 2 1 12 12 10 4 HEAT-like repeat IFRD PF05004.13 EEQ32174.1 - 2e-12 46.9 2.5 0.0012 18.0 0.0 4.5 2 1 3 5 5 5 3 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 EEQ32174.1 - 9e-08 31.6 1.5 8.8e-05 21.8 0.0 3.4 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 EEQ32174.1 - 2e-07 31.2 2.9 0.082 12.9 0.0 4.7 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EEQ32174.1 - 2.6e-07 31.1 0.0 4 8.1 0.0 6.5 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EEQ32174.1 - 7.1e-06 25.7 0.0 0.012 15.2 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal IBN_N PF03810.19 EEQ32174.1 - 1.6e-05 24.7 3.6 3.2e-05 23.8 0.4 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EEQ32174.1 - 0.00055 18.6 0.9 0.35 9.4 0.1 3.2 3 2 0 3 3 3 2 Adaptin N terminal region RIX1 PF08167.12 EEQ32174.1 - 0.00061 19.6 0.3 0.13 12.0 0.0 3.8 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 EEQ32174.1 - 0.00071 19.7 1.2 0.2 11.9 0.0 4.3 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 EEQ32174.1 - 0.0012 19.0 0.2 0.13 12.4 0.0 3.3 3 1 1 4 4 4 1 Parkin co-regulated protein Arm PF00514.23 EEQ32174.1 - 0.0018 18.2 0.0 16 5.7 0.0 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ecm29 PF13001.7 EEQ32174.1 - 0.0033 16.2 0.1 0.14 10.9 0.0 3.2 2 1 0 3 3 3 1 Proteasome stabiliser UNC45-central PF11701.8 EEQ32174.1 - 0.0053 16.7 0.1 0.069 13.1 0.0 2.8 1 1 1 2 2 2 1 Myosin-binding striated muscle assembly central Sec7_N PF12783.7 EEQ32174.1 - 0.0083 16.0 0.0 0.19 11.6 0.0 3.1 3 1 1 4 4 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Cohesin_HEAT PF12765.7 EEQ32174.1 - 0.013 15.7 0.0 0.12 12.7 0.0 2.8 3 0 0 3 3 2 0 HEAT repeat associated with sister chromatid cohesion NUC173 PF08161.12 EEQ32174.1 - 0.037 13.7 0.2 19 4.8 0.0 4.9 4 1 1 5 5 5 0 NUC173 domain NPC1_N PF16414.5 EEQ32175.1 - 2e-83 279.7 8.2 2.9e-83 279.2 8.2 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EEQ32175.1 - 2.2e-74 251.0 13.5 3.6e-73 247.0 13.5 2.1 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EEQ32175.1 - 5e-53 179.0 6.3 5e-53 179.0 6.3 3.0 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EEQ32175.1 - 7.2e-07 28.5 9.8 7.2e-07 28.5 9.8 3.4 3 1 0 3 3 3 1 MMPL family Folate_rec PF03024.14 EEQ32175.1 - 5.1e-05 23.2 3.0 0.0001 22.3 3.0 1.4 1 0 0 1 1 1 1 Folate receptor family DUF2433 PF10360.9 EEQ32176.1 - 4.9e-49 165.6 0.0 8.1e-49 164.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 EEQ32176.1 - 0.00069 20.2 0.0 0.0017 18.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEQ32176.1 - 0.00086 19.5 0.0 0.0037 17.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PAP1 PF08601.10 EEQ32177.1 - 2.2e-91 307.4 45.3 1.3e-88 298.3 33.5 4.1 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 EEQ32177.1 - 1.5e-07 31.4 10.0 3.6e-07 30.2 10.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.12 EEQ32177.1 - 0.015 15.9 2.5 0.037 14.7 2.5 1.7 1 0 0 1 1 1 0 SlyX DUF16 PF01519.16 EEQ32177.1 - 0.02 15.4 2.3 0.042 14.3 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 SHE3 PF17078.5 EEQ32177.1 - 0.049 13.3 3.3 0.087 12.5 3.3 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 IL11 PF07400.11 EEQ32177.1 - 0.063 12.9 1.9 0.14 11.8 1.9 1.5 1 0 0 1 1 1 0 Interleukin 11 TSC22 PF01166.18 EEQ32177.1 - 0.25 11.7 1.1 0.55 10.6 1.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family EMP24_GP25L PF01105.24 EEQ32177.1 - 0.31 11.0 1.3 0.55 10.1 1.3 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TolA_bind_tri PF16331.5 EEQ32177.1 - 0.32 11.1 4.5 0.29 11.2 2.8 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation bZIP_Maf PF03131.17 EEQ32177.1 - 5.1 7.7 16.9 0.23 12.0 10.6 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor CDC45 PF02724.14 EEQ32177.1 - 6.3 5.0 9.5 9.3 4.4 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Tudor_3 PF18115.1 EEQ32178.1 - 8.9e-08 31.9 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EEQ32178.1 - 0.0018 18.3 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 EEQ32178.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain TRAUB PF08164.12 EEQ32179.1 - 2.8e-30 104.7 0.9 7e-30 103.4 0.0 2.2 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EEQ32179.1 - 9.3e-28 97.6 1.4 9.3e-28 97.6 1.4 2.4 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor RRN3 PF05327.11 EEQ32179.1 - 2.9 6.3 10.1 6.5 5.2 10.1 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ParA PF10609.9 EEQ32180.1 - 8.3e-82 274.3 0.0 1.1e-79 267.4 0.0 2.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EEQ32180.1 - 3.3e-12 46.6 0.0 4.6e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EEQ32180.1 - 9.3e-10 38.7 0.2 1e-07 32.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EEQ32180.1 - 2.2e-06 27.1 0.1 3.6e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EEQ32180.1 - 0.00018 20.8 0.4 0.0018 17.5 0.3 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 EEQ32180.1 - 0.0046 16.6 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EEQ32180.1 - 0.06 12.8 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 EEQ32180.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein Abhydrolase_3 PF07859.13 EEQ32181.1 - 6.3e-16 58.9 0.1 4.3e-06 26.7 0.0 3.4 3 0 0 3 3 3 3 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EEQ32181.1 - 0.00069 18.6 0.0 0.96 8.2 0.0 2.3 2 0 0 2 2 2 2 Steryl acetyl hydrolase Pkinase PF00069.25 EEQ32182.1 - 1.5e-14 54.1 0.0 2.7e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32182.1 - 0.0072 15.6 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WGG PF10273.9 EEQ32183.1 - 9.5e-28 96.7 0.1 2e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 EEQ32183.1 - 0.051 13.7 0.2 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain CDC45 PF02724.14 EEQ32183.1 - 3.4 5.8 6.3 3.8 5.7 6.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Tht1 PF04163.12 EEQ32184.1 - 2.3e-05 23.4 1.0 2.3e-05 23.4 1.0 2.3 1 1 1 2 2 2 1 Tht1-like nuclear fusion protein Surfac_D-trimer PF09006.11 EEQ32184.1 - 0.012 15.4 0.1 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Ribosomal_L6 PF00347.23 EEQ32185.1 - 1.7e-21 76.7 0.0 1.3e-09 38.6 0.0 2.6 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 EEQ32186.1 - 5.6e-52 176.9 0.4 1.3e-51 175.7 0.4 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.19 EEQ32187.1 - 8.6e-27 93.7 0.0 1.5e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 VHS domain ENTH PF01417.20 EEQ32187.1 - 0.00014 21.9 0.0 0.00074 19.6 0.0 2.0 2 0 0 2 2 2 1 ENTH domain APH PF01636.23 EEQ32188.1 - 2.1e-09 37.7 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ32188.1 - 0.016 14.1 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF3082 PF11282.8 EEQ32188.1 - 0.032 14.5 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) Choline_kinase PF01633.20 EEQ32188.1 - 0.19 11.3 0.0 0.41 10.2 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Hva1_TUDOR PF11160.8 EEQ32189.1 - 3.6e-19 68.7 0.1 4.1e-19 68.5 0.1 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain CP2 PF04516.15 EEQ32191.1 - 1.8e-64 217.2 0.0 2.7e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Pkinase PF00069.25 EEQ32192.1 - 4.8e-32 111.4 0.0 7e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 EEQ32192.1 - 9.2e-15 55.0 2.4 0.00016 22.2 0.1 4.1 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 EEQ32192.1 - 2.2e-14 53.3 0.0 4.2e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 EEQ32192.1 - 2e-10 40.0 1.9 0.6 10.8 0.1 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EEQ32192.1 - 2.8e-10 40.5 1.9 0.069 13.7 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ32192.1 - 5.3e-07 29.8 0.2 0.03 14.7 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EEQ32192.1 - 0.00016 22.0 2.5 0.58 10.7 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat WW_1 PF18507.1 EEQ32192.1 - 0.022 14.5 0.6 0.059 13.1 0.6 1.8 1 0 0 1 1 1 0 WW domain Glyco_hydro_18 PF00704.28 EEQ32193.1 - 2.7e-40 139.0 0.2 4.6e-40 138.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EEQ32193.1 - 6.9e-10 38.8 0.0 2.6e-05 24.2 0.0 2.9 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 EEQ32193.1 - 2.6e-05 24.6 10.7 2.6e-05 24.6 10.7 3.2 3 0 0 3 3 3 1 Chitin recognition protein DUF957 PF06117.11 EEQ32194.1 - 0.028 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) Aspzincin_M35 PF14521.6 EEQ32194.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.9 1 1 0 1 1 1 0 Lysine-specific metallo-endopeptidase Amb_V_allergen PF03913.13 EEQ32194.1 - 0.43 10.6 1.8 0.66 10.0 0.1 2.1 3 0 0 3 3 3 0 Amb V Allergen LysM PF01476.20 EEQ32195.1 - 2.2e-14 53.2 3.4 8.8e-06 25.7 0.1 4.3 3 2 2 5 5 5 3 LysM domain DEAD PF00270.29 EEQ32196.1 - 2.6e-43 147.8 0.0 5.6e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ32196.1 - 9.3e-27 93.6 0.0 4.1e-26 91.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ32196.1 - 2e-06 27.9 1.1 9.4e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EEQ32196.1 - 0.0014 18.9 1.0 0.098 12.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain AhpC-TSA PF00578.21 EEQ32196.1 - 0.024 14.5 0.1 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 AhpC/TSA family CFIA_Pcf11 PF11526.8 EEQ32196.1 - 0.089 13.3 4.3 0.33 11.5 4.3 1.9 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 FAD_binding_1 PF00667.20 EEQ32197.1 - 3.2e-56 190.4 0.0 4.8e-56 189.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EEQ32197.1 - 1.1e-09 38.9 0.0 3.4e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Bunya_G1 PF03557.15 EEQ32197.1 - 0.14 10.1 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 BCAS2 PF05700.11 EEQ32199.1 - 0.027 14.1 2.4 0.027 14.1 2.4 1.7 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) SHE3 PF17078.5 EEQ32199.1 - 0.045 13.5 3.2 0.055 13.2 3.2 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 RuvC PF02075.17 EEQ32199.1 - 0.091 12.6 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC Mvb12 PF09452.10 EEQ32199.1 - 0.28 11.6 2.8 1.6 9.2 0.1 2.0 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 HNH_2 PF13391.6 EEQ32200.1 - 3.3e-15 56.0 0.1 5.6e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease Peptidase_C1 PF00112.23 EEQ32200.1 - 0.04 14.0 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Papain family cysteine protease Proteasome PF00227.26 EEQ32201.1 - 9.6e-61 204.6 0.1 1.2e-60 204.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEQ32201.1 - 2.7e-13 49.3 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 EEQ32201.1 - 0.018 15.1 0.3 0.049 13.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 EEQ32201.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit WW PF00397.26 EEQ32202.1 - 1.3e-10 41.2 7.4 7.4e-09 35.6 3.4 2.5 2 0 0 2 2 2 2 WW domain FF PF01846.19 EEQ32202.1 - 1.7e-10 40.9 5.6 2.1e-09 37.4 0.1 3.3 3 0 0 3 3 3 2 FF domain DUF5641 PF18701.1 EEQ32202.1 - 0.016 15.3 0.7 0.08 13.1 0.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5641) Seryl_tRNA_N PF02403.22 EEQ32203.1 - 0.031 14.5 3.6 0.077 13.2 3.6 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 EEQ32205.1 - 5.3e-29 101.4 0.0 9.1e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32205.1 - 3.5e-19 69.1 0.0 5e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EEQ32205.1 - 4.2e-07 30.2 0.3 3.4e-06 27.3 0.1 2.4 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EEQ32205.1 - 0.00027 21.2 0.0 0.00074 19.8 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RPS31 PF17067.5 EEQ32205.1 - 0.12 12.6 0.2 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S31e Kinase-like PF14531.6 EEQ32205.1 - 0.14 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SPOC PF07744.13 EEQ32206.1 - 1.4e-24 86.8 0.0 9.1e-24 84.1 0.0 2.1 2 0 0 2 2 2 1 SPOC domain TFIIS_M PF07500.14 EEQ32206.1 - 1.4e-20 73.8 0.0 2.6e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 EEQ32206.1 - 3e-10 39.8 11.1 5.4e-10 39.0 11.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 EEQ32206.1 - 0.016 15.6 1.1 0.062 13.7 1.1 2.0 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 EEQ32206.1 - 0.018 14.6 4.0 0.037 13.6 4.0 1.5 1 0 0 1 1 1 0 PHD-finger Terminase_GpA PF05876.12 EEQ32206.1 - 0.32 9.5 5.4 0.55 8.7 5.4 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zinc_ribbon_10 PF10058.9 EEQ32206.1 - 1.6 8.5 5.8 3.1 7.6 5.8 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein LUC7 PF03194.15 EEQ32207.1 - 9.8e-73 244.9 0.1 1.2e-72 244.6 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.11 EEQ32207.1 - 0.002 17.3 0.5 0.0027 16.8 0.5 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DASH_Duo1 PF08651.10 EEQ32207.1 - 0.063 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 T4SS PF07996.11 EEQ32207.1 - 0.076 13.4 0.1 0.25 11.7 0.0 1.7 1 1 1 2 2 2 0 Type IV secretion system proteins DUF2130 PF09903.9 EEQ32207.1 - 0.096 11.9 0.3 0.16 11.2 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) PP_kinase_N PF13089.6 EEQ32207.1 - 0.13 12.6 0.1 0.51 10.7 0.0 1.9 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain XhlA PF10779.9 EEQ32207.1 - 0.14 12.3 2.1 0.37 11.0 0.8 2.0 2 0 0 2 2 2 0 Haemolysin XhlA MCPsignal PF00015.21 EEQ32207.1 - 0.2 11.4 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Gpi16 PF04113.14 EEQ32208.1 - 2e-234 779.3 0.0 2.5e-234 778.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component MAT1 PF06391.13 EEQ32209.1 - 7.6 6.3 12.4 0.65 9.8 6.6 1.8 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 HECT PF00632.25 EEQ32210.1 - 2.3e-76 257.2 0.0 7e-76 255.6 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.20 EEQ32210.1 - 0.0018 16.9 0.7 0.0031 16.1 0.1 1.6 2 0 0 2 2 2 1 Adaptin N terminal region HEAT PF02985.22 EEQ32210.1 - 0.023 14.9 0.8 4 8.0 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.23 EEQ32210.1 - 0.028 14.5 10.2 16 5.7 0.1 6.3 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EEQ32210.1 - 0.062 13.8 0.1 0.53 10.9 0.0 2.6 2 0 0 2 2 2 0 HEAT-like repeat HAD PF12710.7 EEQ32211.1 - 1.3e-28 100.6 0.0 1.7e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EEQ32211.1 - 0.00029 20.5 0.0 0.0015 18.1 0.0 1.9 1 1 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 EEQ32211.1 - 0.0019 17.6 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 EEQ32211.1 - 0.28 11.5 1.4 17 5.6 1.4 2.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase BTB PF00651.31 EEQ32212.1 - 0.0041 17.3 0.0 0.0074 16.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF1039 PF06287.11 EEQ32212.1 - 0.12 12.8 0.1 2 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1039) RTA1 PF04479.13 EEQ32214.1 - 1.3e-38 132.7 5.1 2.3e-38 131.9 5.1 1.3 1 0 0 1 1 1 1 RTA1 like protein TMEM101 PF15111.6 EEQ32214.1 - 0.0013 18.4 0.2 0.0013 18.4 0.2 1.6 2 0 0 2 2 2 1 TMEM101 protein family Pkinase PF00069.25 EEQ32215.1 - 2.9e-12 46.5 0.1 3.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32215.1 - 0.003 16.9 0.1 0.039 13.2 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 EEQ32215.1 - 0.0059 16.6 0.1 0.037 14.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family tRNA-synt_1g PF09334.11 EEQ32216.1 - 5.3e-139 463.3 0.0 7.6e-139 462.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EEQ32216.1 - 3e-05 22.5 0.6 0.0049 15.2 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EEQ32216.1 - 0.00043 20.3 0.0 0.00085 19.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PDDEXK_9 PF08011.11 EEQ32217.1 - 0.039 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily MbeB_N PF04837.12 EEQ32217.1 - 0.11 12.8 0.2 0.63 10.4 1.0 1.7 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Sulfatase PF00884.23 EEQ32219.1 - 9.7e-66 222.3 0.0 1.4e-49 169.2 0.0 2.1 1 1 1 2 2 2 2 Sulfatase DUF229 PF02995.17 EEQ32219.1 - 0.00077 18.2 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 EEQ32219.1 - 0.018 15.8 0.1 0.47 11.2 0.1 2.5 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 EEQ32219.1 - 0.029 14.3 0.1 0.086 12.8 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function Sugar_tr PF00083.24 EEQ32220.1 - 5.1e-72 243.2 8.7 5.8e-72 243.0 8.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ32220.1 - 9.9e-14 51.0 22.1 2.1e-13 50.0 17.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 EEQ32221.1 - 8.9e-10 38.5 7.1 2.4e-09 37.1 7.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1150 PF06620.11 EEQ32222.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) Abhydrolase_3 PF07859.13 EEQ32224.1 - 1.6e-46 158.8 0.1 2.2e-46 158.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EEQ32224.1 - 3.8e-10 39.2 0.2 9e-10 38.0 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family AATase PF07247.12 EEQ32225.1 - 1e-13 50.7 0.0 2.1e-07 29.9 0.0 2.9 3 0 0 3 3 3 2 Alcohol acetyltransferase Condensation PF00668.20 EEQ32225.1 - 0.063 11.9 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Condensation domain APH PF01636.23 EEQ32226.1 - 4.3e-13 49.7 0.0 6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EEQ32226.1 - 0.0072 15.9 0.0 0.033 13.8 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Fungal_trans PF04082.18 EEQ32227.1 - 1.4e-11 44.0 0.1 3.4e-11 42.7 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EEQ32228.1 - 4.9e-31 107.9 76.5 1.1e-20 73.9 43.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EEQ32228.1 - 0.1 11.4 29.4 0.26 10.1 14.2 2.6 1 1 1 2 2 2 0 MFS_1 like family DUF1435 PF07256.12 EEQ32228.1 - 0.71 10.0 9.5 0.61 10.2 3.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) AMP-binding PF00501.28 EEQ32229.1 - 2.3e-70 237.3 0.1 3.7e-70 236.6 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EEQ32229.1 - 1.2e-12 47.6 0.0 1.3e-08 34.4 0.0 2.8 1 1 1 2 2 2 2 Male sterility protein PP-binding PF00550.25 EEQ32229.1 - 1.2e-09 38.3 0.0 4.3e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 EEQ32229.1 - 3.6e-06 26.6 0.0 6.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EEQ32229.1 - 0.043 12.9 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain CDC45 PF02724.14 EEQ32230.1 - 0.21 9.9 11.7 0.28 9.4 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 EEQ32230.1 - 9.6 5.9 11.5 5.3 6.8 9.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) VCBS PF13517.6 EEQ32232.1 - 6.4e-20 71.5 13.8 8.9e-10 39.0 1.3 4.1 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EEQ32232.1 - 2.9e-15 56.1 1.7 0.0045 17.1 0.4 4.8 4 0 0 4 4 4 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 EEQ32232.1 - 6.3e-09 35.4 0.1 0.091 12.1 0.0 4.1 3 1 1 4 4 4 4 Insecticide toxin TcdB middle/N-terminal region Dockerin_1 PF00404.18 EEQ32232.1 - 2.4e-07 30.8 0.2 1.7 8.9 0.0 4.5 4 0 0 4 4 4 3 Dockerin type I domain PliI PF16743.5 EEQ32232.1 - 0.00012 21.9 0.0 3.1 7.5 0.0 4.0 4 0 0 4 4 4 2 Periplasmic lysozyme inhibitor of I-type lysozyme DUF1918 PF08940.11 EEQ32232.1 - 0.00068 19.2 0.0 0.3 10.7 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF1918) GHL13 PF14883.6 EEQ32232.1 - 0.016 14.3 2.3 0.32 10.0 0.1 3.3 4 0 0 4 4 4 0 Hypothetical glycosyl hydrolase family 13 EF-hand_5 PF13202.6 EEQ32232.1 - 0.053 13.0 13.0 14 5.4 0.1 4.4 4 0 0 4 4 4 0 EF hand FAD_binding_3 PF01494.19 EEQ32233.1 - 3.2e-14 53.0 0.9 7.6e-05 22.1 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 EEQ32233.1 - 0.0013 18.9 0.0 0.0033 17.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ32233.1 - 0.012 15.3 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EEQ32233.1 - 0.03 13.4 0.0 0.064 12.3 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EEQ32233.1 - 0.12 11.3 0.1 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein EthD PF07110.11 EEQ32234.1 - 3.2e-21 76.3 0.1 3.9e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EEQ32234.1 - 0.0053 17.2 0.1 0.013 16.0 0.1 1.6 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase ketoacyl-synt PF00109.26 EEQ32235.1 - 1.9e-77 260.3 0.0 7.9e-77 258.3 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EEQ32235.1 - 7.4e-73 245.2 0.1 8.7e-72 241.7 0.0 2.6 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EEQ32235.1 - 9.4e-39 133.8 0.0 1.5e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ32235.1 - 1.7e-32 111.9 0.3 4e-32 110.7 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EEQ32235.1 - 1e-23 84.6 0.1 1.7e-22 80.7 0.0 2.9 3 0 0 3 3 3 1 Thioesterase domain PP-binding PF00550.25 EEQ32235.1 - 3e-23 82.0 2.4 2.5e-10 40.5 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 EEQ32235.1 - 1.8e-14 53.7 0.0 3.2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EEQ32235.1 - 3.5e-10 40.3 0.0 8.7e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 EEQ32235.1 - 3.1e-07 31.2 2.1 8e-05 23.3 0.5 3.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 EEQ32235.1 - 4.1e-05 23.1 0.1 0.00019 20.9 0.0 2.1 3 0 0 3 3 3 1 Thiolase, N-terminal domain DUF2974 PF11187.8 EEQ32235.1 - 0.034 13.7 0.0 0.09 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MFS_1 PF07690.16 EEQ32236.1 - 7.6e-40 136.9 36.3 1.2e-39 136.3 36.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Imm_superinfect PF14373.6 EEQ32236.1 - 0.25 11.3 4.6 0.48 10.4 1.9 2.6 2 0 0 2 2 2 0 Superinfection immunity protein Nitroreductase PF00881.24 EEQ32237.1 - 2.1e-12 47.4 0.0 2.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Cytochrom_C552 PF02335.15 EEQ32237.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c552 AflR PF08493.10 EEQ32238.1 - 2.4e-05 23.9 0.1 3.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Thioesterase PF00975.20 EEQ32239.1 - 6.2e-22 78.9 0.0 3.1e-19 70.0 0.0 2.1 1 1 0 2 2 2 2 Thioesterase domain DUF2974 PF11187.8 EEQ32239.1 - 0.0016 18.1 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EEQ32239.1 - 0.0033 18.1 0.2 0.022 15.4 0.1 1.9 1 1 2 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ32239.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ32239.1 - 0.027 13.7 0.1 0.068 12.4 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Beta-lactamase PF00144.24 EEQ32240.1 - 4.2e-19 69.0 0.1 3.9e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase PTase_Orf2 PF11468.8 EEQ32241.1 - 7.6e-75 252.0 0.0 9.2e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Aromatic prenyltransferase Orf2 Cu-oxidase_3 PF07732.15 EEQ32242.1 - 6e-19 68.2 0.1 1.3e-18 67.2 0.1 1.5 1 1 0 1 1 1 1 Multicopper oxidase Kinesin PF00225.23 EEQ32243.1 - 8.6e-90 301.0 0.0 1.9e-89 299.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ32243.1 - 1e-09 38.5 1.8 2e-09 37.5 0.0 2.3 3 0 0 3 3 3 1 Microtubule binding DUF5094 PF17015.5 EEQ32243.1 - 0.11 12.6 6.4 0.25 11.4 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) YabA PF06156.13 EEQ32243.1 - 0.95 10.1 4.7 2.9 8.6 4.7 1.9 1 0 0 1 1 1 0 Initiation control protein YabA DUF1460 PF07313.12 EEQ32243.1 - 1.6 8.0 7.0 0.098 12.0 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) BPL_N PF09825.9 EEQ32243.1 - 1.9 7.5 4.2 4.2 6.4 4.0 1.7 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal IF-2B PF01008.17 EEQ32244.1 - 8.9e-71 238.4 0.1 1.1e-70 238.0 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Ndc1_Nup PF09531.10 EEQ32244.1 - 0.32 9.7 7.3 0.48 9.1 7.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apc13p PF05839.11 EEQ32245.1 - 1.1e-18 67.2 0.8 2.7e-15 56.3 0.0 2.2 1 1 0 2 2 2 2 Apc13p protein Pol_alpha_B_N PF08418.10 EEQ32246.1 - 6e-81 272.0 0.1 7.6e-81 271.7 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EEQ32246.1 - 1.6e-33 115.9 0.0 2.2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.20 EEQ32247.1 - 3.3e-35 121.2 0.0 4.6e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ32247.1 - 1.2e-14 54.2 0.1 4.1e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEQ32247.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CBS PF00571.28 EEQ32248.1 - 1.5e-16 60.6 8.7 3.8e-08 33.6 0.4 3.8 4 0 0 4 4 4 3 CBS domain RhoGAP PF00620.27 EEQ32249.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain DUF3683 PF12447.8 EEQ32249.1 - 0.2 11.8 0.4 0.67 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) bZIP_Maf PF03131.17 EEQ32250.1 - 9.3 6.9 17.7 19 5.9 16.5 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor ECH_2 PF16113.5 EEQ32251.1 - 2.2e-129 431.7 0.0 3.2e-129 431.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EEQ32251.1 - 5.1e-27 94.8 0.0 3.2e-26 92.2 0.0 2.2 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase ELF PF03317.13 EEQ32251.1 - 0.14 12.2 0.1 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 ELF protein Ribosomal_L4 PF00573.22 EEQ32252.1 - 8.1e-46 156.1 0.0 1.2e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.20 EEQ32253.1 - 4e-06 27.2 0.0 6.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran_Xtn PF12848.7 EEQ32253.1 - 0.98 9.5 6.3 2.1 8.4 6.3 1.5 1 0 0 1 1 1 0 ABC transporter Peptidase_S24 PF00717.23 EEQ32254.1 - 8.1e-08 32.1 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EEQ32254.1 - 0.0017 18.1 0.0 0.027 14.2 0.0 2.2 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Lactamase_B PF00753.27 EEQ32255.1 - 5.7e-17 62.4 5.8 5.9e-16 59.1 5.8 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 EEQ32255.1 - 2.5e-07 31.1 0.0 4.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 EEQ32255.1 - 0.0064 16.0 3.1 0.066 12.7 3.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 EEQ32255.1 - 0.081 12.4 0.1 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Las1 PF04031.13 EEQ32256.1 - 2.2e-48 164.2 0.4 3.9e-48 163.5 0.4 1.4 1 0 0 1 1 1 1 Las1-like NAD_kinase PF01513.21 EEQ32259.1 - 2.1e-73 247.1 0.0 2.8e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EEQ32259.1 - 0.097 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TRAPP PF04051.16 EEQ32260.1 - 1.2e-39 135.3 0.0 1.7e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component MFAP1 PF06991.11 EEQ32261.1 - 1e-67 228.2 16.9 1e-67 228.2 16.9 2.7 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing Glyco_hydro_16 PF00722.21 EEQ32262.1 - 2.9e-44 150.7 1.7 4.5e-44 150.0 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Rep_fac-A_3 PF08661.11 EEQ32263.1 - 5.7e-17 62.0 0.0 6.1e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 GATA PF00320.27 EEQ32264.1 - 2.1e-05 24.0 4.3 0.0013 18.3 0.5 2.6 2 0 0 2 2 2 2 GATA zinc finger zf-RING_7 PF02591.15 EEQ32264.1 - 0.16 12.2 2.3 0.22 11.8 0.8 2.1 2 0 0 2 2 2 0 C4-type zinc ribbon domain LSM PF01423.22 EEQ32265.1 - 6e-19 67.5 0.1 8.4e-19 67.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain CAV_VP3 PF04771.12 EEQ32265.1 - 0.17 12.0 0.0 12 6.1 0.0 2.0 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein Dak1 PF02733.17 EEQ32266.1 - 1.3e-104 349.5 0.8 1.8e-104 349.0 0.8 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EEQ32266.1 - 1.1e-50 172.0 0.1 5.5e-50 169.7 0.1 2.1 2 0 0 2 2 2 1 DAK2 domain Cullin PF00888.22 EEQ32267.1 - 2.5e-178 594.6 3.4 3.1e-178 594.2 3.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EEQ32267.1 - 5.7e-24 83.9 2.0 1.6e-23 82.5 2.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.11 EEQ32267.1 - 0.02 14.9 0.1 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 HbrB-like Nup192 PF11894.8 EEQ32268.1 - 0 1241.6 24.9 0 1090.8 12.3 2.0 1 1 1 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 PI3_PI4_kinase PF00454.27 EEQ32269.1 - 9.8e-51 173.0 0.1 2.6e-50 171.6 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EEQ32269.1 - 3.8e-45 153.7 0.5 1.1e-44 152.2 0.5 1.9 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EEQ32269.1 - 4.1e-07 29.7 0.3 1e-06 28.4 0.3 1.8 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EEQ32269.1 - 5.7e-05 22.5 6.0 0.00017 20.9 6.0 1.8 1 0 0 1 1 1 1 FAT domain UPF0052 PF01933.18 EEQ32270.1 - 8.8e-57 192.6 0.0 1.1e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_2 PF13923.6 EEQ32271.1 - 0.00078 19.2 3.8 0.011 15.5 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EEQ32271.1 - 0.01 15.7 0.3 0.74 9.7 0.0 2.5 2 0 0 2 2 2 1 Rad50 zinc hook motif Prok-RING_4 PF14447.6 EEQ32271.1 - 0.024 14.5 1.0 0.71 9.8 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 EEQ32271.1 - 0.075 13.3 0.4 11 6.3 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SART-1 PF03343.13 EEQ32271.1 - 0.11 11.1 0.4 0.12 10.9 0.4 1.1 1 0 0 1 1 1 0 SART-1 family zf-C3HC4_3 PF13920.6 EEQ32271.1 - 0.13 12.2 5.9 1.7 8.6 5.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEQ32271.1 - 0.23 11.6 1.9 1.1 9.5 0.4 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EEQ32271.1 - 0.29 11.5 3.9 2.1 8.7 4.1 2.1 1 1 0 1 1 1 0 Ring finger domain DUF5318 PF17249.2 EEQ32271.1 - 0.32 10.8 1.2 0.94 9.3 1.2 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5318) DNApol_Exo PF18136.1 EEQ32272.1 - 1.2e-105 352.7 0.0 1.9e-105 352.0 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EEQ32272.1 - 4.3e-58 197.2 0.0 7.6e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A TFIIS_M PF07500.14 EEQ32272.1 - 0.023 15.2 0.6 0.085 13.4 0.6 1.9 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain DNA_pol_A_exo1 PF01612.20 EEQ32272.1 - 0.031 14.0 0.1 0.59 9.8 0.1 2.4 1 1 0 1 1 1 0 3'-5' exonuclease Mad3_BUB1_I PF08311.12 EEQ32272.1 - 0.082 12.9 0.2 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 CorA PF01544.18 EEQ32273.1 - 1.8e-22 80.1 2.5 5.1e-14 52.3 0.1 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein BORCS6 PF10157.9 EEQ32273.1 - 0.049 13.9 4.0 0.56 10.4 0.1 3.0 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 6 YqfQ PF14181.6 EEQ32273.1 - 0.29 11.3 1.3 0.55 10.4 1.3 1.4 1 0 0 1 1 1 0 YqfQ-like protein Pep1_7 PF17232.2 EEQ32273.1 - 1.2 9.7 5.9 4.3 7.9 2.3 2.7 2 0 0 2 2 2 0 Elicitor peptide 1-7 SQS_PSY PF00494.19 EEQ32274.1 - 5.1e-51 173.7 0.0 9.7e-51 172.8 0.0 1.5 1 1 0 1 1 1 1 Squalene/phytoene synthase Soyouz_module PF14313.6 EEQ32274.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) SNF2_N PF00176.23 EEQ32275.1 - 6.8e-71 238.8 0.0 9.7e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EEQ32275.1 - 9.8e-24 83.1 0.0 1.9e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EEQ32275.1 - 3e-13 50.1 0.0 7.9e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ32275.1 - 3.5e-07 30.4 0.0 9.3e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 EEQ32275.1 - 0.00016 21.4 9.7 0.00029 20.6 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ32275.1 - 0.0016 18.3 5.7 0.0038 17.0 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ32275.1 - 0.0032 17.3 13.5 0.0068 16.2 13.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ32275.1 - 0.021 14.8 12.3 0.048 13.7 12.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ32275.1 - 0.041 13.8 11.8 0.085 12.8 11.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EEQ32275.1 - 0.1 12.9 14.2 0.095 13.0 12.5 2.0 2 0 0 2 2 1 0 Ring finger domain ParG PF09274.10 EEQ32275.1 - 0.12 12.6 0.2 0.7 10.1 0.1 2.3 2 0 0 2 2 2 0 ParG zf-C3HC4_5 PF17121.5 EEQ32275.1 - 0.3 11.0 3.3 0.69 9.8 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEQ32275.1 - 0.45 10.7 12.6 0.93 9.7 12.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EEQ32275.1 - 3.6 7.5 12.2 18 5.3 12.5 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Lyase_1 PF00206.20 EEQ32276.1 - 7.6e-22 78.1 0.1 1.2e-21 77.4 0.1 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EEQ32276.1 - 3.1e-17 62.9 0.0 9e-17 61.4 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus GTP_EFTU PF00009.27 EEQ32278.1 - 2.2e-20 73.0 0.1 6.9e-20 71.4 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EEQ32278.1 - 9.4e-07 29.1 0.8 3.5e-06 27.3 0.8 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EEQ32278.1 - 4.7e-05 23.7 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EEQ32278.1 - 0.0034 17.5 0.1 0.011 15.8 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ32278.1 - 0.0034 17.3 0.1 2.9 7.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EEQ32278.1 - 0.0046 16.7 0.3 2.4 7.9 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EEQ32278.1 - 0.0087 16.3 0.2 0.26 11.5 0.1 2.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EEQ32278.1 - 0.13 12.4 3.1 0.49 10.4 0.7 2.5 2 1 0 2 2 2 0 Dynamin family Septin PF00735.18 EEQ32278.1 - 0.13 11.5 0.1 0.67 9.2 0.0 2.2 3 0 0 3 3 3 0 Septin ATP-synt_G PF04718.15 EEQ32278.1 - 0.33 11.8 1.0 1.4 9.8 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial ATP synthase g subunit LSM PF01423.22 EEQ32279.1 - 2.7e-14 52.6 0.2 3.8e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.7 EEQ32280.1 - 1.6e-26 92.4 0.1 6.3e-26 90.5 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ATPase expression PPR_3 PF13812.6 EEQ32280.1 - 8.3e-07 29.0 0.0 7.7e-06 25.9 0.0 2.4 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 EEQ32280.1 - 1.3e-05 25.3 0.0 0.15 12.2 0.1 3.3 3 0 0 3 3 3 2 PPR repeat family Csc2 PF18320.1 EEQ32280.1 - 0.016 14.2 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Csc2 Crispr PPR PF01535.20 EEQ32280.1 - 0.054 13.8 0.2 5.7 7.4 0.1 3.4 3 0 0 3 3 3 0 PPR repeat PIG-L PF02585.17 EEQ32281.1 - 7e-28 97.9 0.0 1e-27 97.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Pkinase_Tyr PF07714.17 EEQ32282.1 - 6.3e-11 42.1 0.0 1.1e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EEQ32282.1 - 1.3e-10 41.1 0.0 6e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EEQ32282.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEQ32282.1 - 0.03 13.9 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EEQ32282.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF5132 PF17195.4 EEQ32283.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) DUF3761 PF12587.8 EEQ32283.1 - 0.1 13.1 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) DnaJ PF00226.31 EEQ32284.1 - 2.1e-19 69.4 0.4 5.7e-19 68.0 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 EEQ32284.1 - 0.0059 16.4 0.1 0.018 14.8 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mei4 PF13971.6 EEQ32285.1 - 9.2e-06 25.4 0.3 1.3e-05 24.8 0.3 1.5 1 1 0 1 1 1 1 Meiosis-specific protein Mei4 GCV_T PF01571.21 EEQ32286.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DCP2 PF05026.13 EEQ32287.1 - 3.5e-31 107.3 1.4 6.9e-31 106.4 1.4 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EEQ32287.1 - 7.1e-17 61.7 0.1 1.3e-16 60.8 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain LysM PF01476.20 EEQ32288.1 - 0.004 17.2 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 LysM domain NDUF_B5 PF09781.9 EEQ32288.1 - 0.055 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Mucin PF01456.17 EEQ32288.1 - 0.19 11.7 36.4 0.03 14.3 32.3 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein MGC-24 PF05283.11 EEQ32288.1 - 1.2 9.6 13.1 2 8.9 13.1 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SOG2 PF10428.9 EEQ32288.1 - 1.2 8.2 11.7 1.3 8.1 11.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4112 PF13430.6 EEQ32289.1 - 6.7e-36 122.7 0.3 8.8e-36 122.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CTU2 PF10288.9 EEQ32290.1 - 1.2e-10 41.7 0.3 7.2e-10 39.1 0.3 2.1 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Lung_7-TM_R PF06814.13 EEQ32291.1 - 7.6e-73 245.3 19.7 9.5e-73 245.0 19.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF1308 PF07000.11 EEQ32292.1 - 4.8e-12 46.1 0.0 2.5e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) WD40 PF00400.32 EEQ32293.1 - 1.2e-14 54.5 1.8 1.5e-05 25.6 0.1 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ32293.1 - 3.2e-06 27.3 0.0 0.0045 17.2 0.0 3.8 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TruB_C PF09142.11 EEQ32293.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Mito_carr PF00153.27 EEQ32294.1 - 1.3e-51 172.5 3.8 8.9e-17 60.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_red_sm PF00268.21 EEQ32296.1 - 1.6e-116 388.7 0.8 1.9e-116 388.4 0.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 EEQ32297.1 - 1e-32 112.4 3.8 2.5e-32 111.1 3.8 1.7 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.32 EEQ32297.1 - 2.4e-25 88.3 4.9 0.00011 22.9 0.2 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ32297.1 - 2.6e-06 27.7 0.2 2.3 8.6 0.1 4.7 3 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ32297.1 - 0.013 14.2 0.2 1.2 7.7 0.4 2.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ32297.1 - 0.018 14.0 0.0 2.4 7.1 0.0 2.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CBM_19 PF03427.13 EEQ32297.1 - 0.16 11.9 0.4 0.96 9.5 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) APH PF01636.23 EEQ32298.1 - 1.5e-12 48.0 0.4 5.1e-08 33.1 0.1 2.5 3 0 0 3 3 3 2 Phosphotransferase enzyme family EcKinase PF02958.20 EEQ32298.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase OHCU_decarbox PF09349.10 EEQ32299.1 - 1.3e-38 133.0 0.0 1.7e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF3684 PF12449.8 EEQ32299.1 - 0.11 10.2 0.0 0.16 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) TruB_N PF01509.18 EEQ32301.1 - 2.7e-44 151.1 0.0 1.2e-43 149.1 0.0 1.9 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EEQ32301.1 - 1.7e-07 31.3 0.0 4.3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain SWIRM-assoc_2 PF16496.5 EEQ32301.1 - 0.029 13.3 3.2 0.043 12.7 3.2 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DNMT1-RFD PF12047.8 EEQ32302.1 - 0.019 15.0 3.4 0.053 13.6 0.0 2.9 3 0 0 3 3 3 0 Cytosine specific DNA methyltransferase replication foci domain Neuregulin PF02158.15 EEQ32302.1 - 0.06 12.7 7.9 0.12 11.7 7.9 1.5 1 0 0 1 1 1 0 Neuregulin intracellular region E3_UbLigase_EDD PF11547.8 EEQ32302.1 - 0.061 13.0 0.6 0.51 10.1 0.3 2.4 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD Drc1-Sld2 PF11719.8 EEQ32302.1 - 0.11 12.0 14.2 0.22 11.0 14.2 1.5 1 0 0 1 1 1 0 DNA replication and checkpoint protein Sporozoite_P67 PF05642.11 EEQ32302.1 - 0.13 10.4 6.0 0.21 9.7 6.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 EEQ32302.1 - 0.46 8.7 11.6 0.71 8.1 11.6 1.3 1 0 0 1 1 1 0 CDC45-like protein IBR PF01485.21 EEQ32302.1 - 1.5 9.1 6.9 8.2 6.7 0.1 3.2 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain Presenilin PF01080.17 EEQ32302.1 - 6.6 5.4 6.4 9.9 4.8 6.4 1.2 1 0 0 1 1 1 0 Presenilin Ebp2 PF05890.12 EEQ32303.1 - 9.8e-94 313.8 15.7 9.8e-94 313.8 15.7 2.2 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Thioredoxin PF00085.20 EEQ32304.1 - 1.5e-55 185.5 0.0 4.9e-28 97.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EEQ32304.1 - 2.7e-23 82.7 2.0 3.5e-23 82.3 0.6 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EEQ32304.1 - 1.6e-13 51.0 0.0 3.3e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EEQ32304.1 - 6.3e-12 45.4 0.0 2.1e-05 24.0 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EEQ32304.1 - 1.6e-07 31.4 0.0 0.0012 19.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EEQ32304.1 - 3.3e-06 27.3 0.0 0.25 11.7 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 EEQ32304.1 - 1.4e-05 25.0 0.0 0.098 12.6 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 EEQ32304.1 - 5.4e-05 23.1 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EEQ32304.1 - 0.00085 19.1 0.0 0.28 11.0 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 EEQ32304.1 - 0.0062 16.5 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Glutaredoxin PF00462.24 EEQ32304.1 - 0.01 16.0 0.0 5.4 7.3 0.1 2.8 2 1 0 2 2 2 0 Glutaredoxin HyaE PF07449.11 EEQ32304.1 - 0.037 14.0 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.6 EEQ32304.1 - 0.13 12.5 1.6 17 5.5 0.2 3.5 3 1 0 3 3 3 0 Thioredoxin MKT1_C PF12246.8 EEQ32305.1 - 2e-82 276.1 0.0 3.5e-82 275.2 0.0 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EEQ32305.1 - 2e-31 108.2 0.0 6.1e-31 106.6 0.0 1.9 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 EEQ32305.1 - 6.5e-06 26.4 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EEQ32305.1 - 0.055 13.9 0.0 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 XPG N-terminal domain GIT_SHD PF08518.11 EEQ32305.1 - 0.088 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT 2OG-FeII_Oxy PF03171.20 EEQ32306.1 - 1.2e-14 54.7 0.0 3.5e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EEQ32306.1 - 1.4e-11 45.2 0.1 2e-11 44.7 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WD40 PF00400.32 EEQ32308.1 - 1.3e-34 117.6 18.6 1.4e-06 28.9 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ32308.1 - 6.5e-15 55.2 0.0 0.00049 20.3 0.1 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ32308.1 - 0.006 15.6 0.4 2.6 6.9 0.0 3.1 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CFEM PF05730.11 EEQ32309.1 - 4.5e-12 45.9 12.2 8.9e-12 44.9 12.2 1.5 1 0 0 1 1 1 1 CFEM domain Phosducin PF02114.16 EEQ32311.1 - 4.4e-10 39.0 0.0 1e-07 31.2 0.0 2.7 2 1 0 2 2 2 2 Phosducin YEATS PF03366.16 EEQ32312.1 - 2.1e-18 66.1 0.0 3.7e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EEQ32312.1 - 4.3e-06 26.8 0.3 7.7e-06 26.0 0.3 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ran_BP1 PF00638.18 EEQ32313.1 - 1.6e-35 122.0 8.2 1.6e-35 122.0 8.2 2.4 2 1 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 EEQ32313.1 - 0.019 14.9 0.3 0.093 12.7 0.3 1.9 1 1 0 1 1 1 0 WH1 domain CDC27 PF09507.10 EEQ32313.1 - 0.067 12.6 23.1 0.087 12.2 23.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Phospholamban PF04272.14 EEQ32314.1 - 0.95 9.0 3.3 2.5 7.6 2.1 2.2 2 0 0 2 2 2 0 Phospholamban Caveolin PF01146.17 EEQ32314.1 - 1.2 9.1 3.6 2.7 7.9 3.6 1.5 1 0 0 1 1 1 0 Caveolin PBP1_TM PF14812.6 EEQ32314.1 - 1.5 9.3 4.9 0.79 10.1 0.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EEQ32314.1 - 5.4 7.5 8.0 16 5.9 1.2 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Glyco_transf_15 PF01793.16 EEQ32316.1 - 2.4e-96 322.8 13.4 8e-96 321.1 13.4 1.7 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Peptidase_S58 PF03576.14 EEQ32317.1 - 7e-112 373.8 1.9 8e-112 373.6 1.9 1.0 1 0 0 1 1 1 1 Peptidase family S58 APH PF01636.23 EEQ32320.1 - 5e-09 36.4 0.0 1.2e-08 35.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 EEQ32320.1 - 0.004 17.3 7.7 0.0073 16.4 7.7 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger PH PF00169.29 EEQ32321.1 - 1.5e-29 102.6 1.4 4.8e-15 56.0 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 EEQ32321.1 - 5.7e-13 49.3 4.4 6.7e-08 32.9 0.2 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 EEQ32321.1 - 3.9e-08 33.7 6.3 0.0012 19.2 0.2 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 EEQ32321.1 - 3.7e-05 24.0 0.1 0.0036 17.6 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PBP_N PF17093.5 EEQ32321.1 - 0.026 14.8 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus NCOA_u2 PF16665.5 EEQ32321.1 - 0.034 14.5 0.6 0.073 13.4 0.6 1.5 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein PH_13 PF16652.5 EEQ32321.1 - 0.046 13.5 0.2 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 EEQ32321.1 - 0.068 13.5 1.1 2.1 8.7 0.0 2.6 3 1 0 3 3 3 0 Plant pleckstrin homology-like region UIM PF02809.20 EEQ32321.1 - 0.18 11.8 0.7 0.42 10.6 0.7 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DOT1 PF08123.13 EEQ32322.1 - 2.4e-75 252.6 0.0 3.8e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EEQ32322.1 - 0.0015 19.2 0.1 0.0067 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.6 EEQ32322.1 - 0.026 14.4 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Methyltransf_31 PF13847.6 EEQ32322.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.13 EEQ32322.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family CytochromB561_N PF09786.9 EEQ32322.1 - 2.9 6.8 11.3 4.3 6.2 11.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal ATG16 PF08614.11 EEQ32323.1 - 4e-51 174.1 15.9 4.5e-51 173.9 15.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) JHY PF15261.6 EEQ32323.1 - 0.00072 20.3 1.3 0.00072 20.3 1.3 1.6 2 0 0 2 2 2 1 Jhy protein CortBP2 PF09727.9 EEQ32323.1 - 0.035 14.0 13.2 0.015 15.2 10.8 1.6 1 1 0 2 2 2 0 Cortactin-binding protein-2 Sec34 PF04136.15 EEQ32323.1 - 0.14 12.0 3.5 4 7.3 0.1 2.3 2 0 0 2 2 2 0 Sec34-like family HNOBA PF07701.14 EEQ32323.1 - 0.28 10.6 6.3 0.65 9.4 0.5 2.3 2 0 0 2 2 2 0 Heme NO binding associated GvpG PF05120.12 EEQ32323.1 - 0.43 10.6 7.0 0.18 11.8 0.5 2.4 2 0 0 2 2 2 0 Gas vesicle protein G UPF0242 PF06785.11 EEQ32323.1 - 0.47 10.5 13.1 1 9.4 1.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 EEQ32323.1 - 0.97 8.7 10.2 1.4 8.2 10.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 EEQ32323.1 - 1.1 9.9 9.8 1 10.0 1.9 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 EEQ32323.1 - 1.4 7.9 6.4 2.1 7.4 6.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DHR10 PF18595.1 EEQ32323.1 - 3.8 7.6 20.0 3.6 7.7 7.9 2.7 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 EEQ32323.1 - 5 7.7 14.7 1.8 9.1 11.2 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region Ras PF00071.22 EEQ32324.1 - 5.9e-56 188.5 0.2 7.1e-56 188.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ32324.1 - 1.1e-31 109.5 0.0 1.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ32324.1 - 1e-13 51.1 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEQ32324.1 - 8.8e-08 32.2 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEQ32324.1 - 3e-07 30.0 0.0 3.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EEQ32324.1 - 1.3e-06 28.2 0.1 5.8e-05 22.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ32324.1 - 8.7e-05 22.5 0.2 0.0032 17.4 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 EEQ32324.1 - 0.0029 17.4 0.1 0.084 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EEQ32324.1 - 0.0042 16.7 0.0 0.014 15.0 0.0 1.7 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EEQ32324.1 - 0.0073 16.3 0.1 0.013 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EEQ32324.1 - 0.0085 15.9 0.3 0.2 11.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EEQ32324.1 - 0.0088 16.3 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 EEQ32324.1 - 0.0091 15.3 0.3 0.047 13.0 0.0 2.1 3 0 0 3 3 3 1 Septin AAA_16 PF13191.6 EEQ32324.1 - 0.0096 16.3 0.0 0.015 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 EEQ32324.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EEQ32324.1 - 0.018 14.6 0.1 0.034 13.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EEQ32324.1 - 0.022 14.5 0.1 0.054 13.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EEQ32324.1 - 0.061 13.2 1.2 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EEQ32324.1 - 0.064 13.2 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase TniB PF05621.11 EEQ32324.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EEQ32324.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EEQ32324.1 - 0.18 12.3 0.1 0.39 11.2 0.0 1.6 2 0 0 2 2 2 0 ABC transporter DUF3955 PF13127.6 EEQ32325.1 - 6.7e-06 25.8 1.4 6.7e-06 25.8 1.4 4.2 6 0 0 6 6 6 1 Protein of unknown function (DUF3955) EamA PF00892.20 EEQ32325.1 - 0.00011 22.3 33.5 0.0038 17.4 16.6 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF2981 PF11200.8 EEQ32325.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Spb1_C PF07780.12 EEQ32326.1 - 3.8e-84 281.5 22.2 3.8e-84 281.5 22.2 2.6 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EEQ32326.1 - 5e-55 186.4 0.0 9.4e-55 185.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EEQ32326.1 - 9.4e-51 171.9 10.3 9.4e-51 171.9 10.3 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 EEQ32326.1 - 0.0016 18.3 0.0 0.0053 16.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EEQ32326.1 - 0.014 15.1 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PcfJ PF14284.6 EEQ32326.1 - 2.4 8.0 7.2 0.29 11.0 1.7 2.3 2 0 0 2 2 2 0 PcfJ-like protein Zn_clus PF00172.18 EEQ32328.1 - 4.1e-07 30.0 10.5 8.1e-07 29.1 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ32328.1 - 0.0076 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_4 PF12763.7 EEQ32329.1 - 0.0042 17.0 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF3632 PF12311.8 EEQ32330.1 - 6.2e-24 85.4 0.4 7.9e-24 85.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Pkinase PF00069.25 EEQ32331.1 - 1.1e-70 238.0 0.0 1.4e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32331.1 - 3.7e-33 114.9 0.0 5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EEQ32331.1 - 4.9e-09 36.8 2.4 1.4e-08 35.3 2.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EEQ32331.1 - 1.1e-05 24.5 0.1 1.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EEQ32331.1 - 0.032 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EEQ32331.1 - 0.074 12.7 0.1 0.84 9.2 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 C2 PF00168.30 EEQ32331.1 - 0.16 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 C2 domain DNA_ligase_A_M PF01068.21 EEQ32332.1 - 9.1e-48 162.6 0.0 1.1e-46 159.1 0.0 2.6 3 1 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EEQ32332.1 - 7.9e-42 143.5 0.0 4.3e-41 141.1 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 EEQ32332.1 - 1.2e-19 70.5 0.2 3.7e-13 49.7 0.1 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 EEQ32332.1 - 4e-17 62.6 0.0 1.4e-16 60.9 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EEQ32332.1 - 7.5e-17 62.1 0.0 1.6e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 EEQ32332.1 - 7.2e-08 32.7 0.3 8e-05 22.9 0.0 2.9 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EEQ32332.1 - 1.8e-07 31.3 0.2 0.0039 17.4 0.0 2.7 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EEQ32332.1 - 4.6e-05 23.3 0.1 0.19 11.7 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain RTT107_BRCT_5 PF16770.5 EEQ32332.1 - 0.00081 19.2 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain DNA_ligase_IV PF11411.8 EEQ32332.1 - 0.0084 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase IV Fungal_trans PF04082.18 EEQ32333.1 - 6.5e-48 163.1 0.0 1.4e-47 162.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Metallophos PF00149.28 EEQ32334.1 - 3.6e-32 112.5 0.0 2.4e-22 80.5 0.0 2.2 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEQ32334.1 - 0.011 16.1 0.1 0.029 14.8 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 EEQ32335.1 - 0.042 13.9 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 Peptidase_A21 PF03566.13 EEQ32335.1 - 0.048 11.9 0.4 0.061 11.6 0.4 1.0 1 0 0 1 1 1 0 Peptidase family A21 DUF4646 PF15496.6 EEQ32336.1 - 5e-17 62.7 0.0 7.9e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) ALG3 PF05208.13 EEQ32337.1 - 1.4e-137 458.9 20.8 1.6e-137 458.7 20.8 1.0 1 0 0 1 1 1 1 ALG3 protein TERT_thumb PF17984.1 EEQ32337.1 - 0.11 12.4 0.4 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain eIF-1a PF01176.19 EEQ32338.1 - 1.1e-19 69.9 0.1 1.8e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 SNN_linker PF09050.10 EEQ32338.1 - 0.098 12.4 0.6 0.23 11.3 0.6 1.6 1 0 0 1 1 1 0 Stannin unstructured linker Pkinase PF00069.25 EEQ32339.1 - 1e-59 202.1 0.1 2.6e-59 200.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32339.1 - 4.8e-35 121.1 0.0 8.5e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EEQ32339.1 - 5.1e-29 100.2 13.8 2.9e-15 56.1 4.5 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EEQ32339.1 - 2.2e-15 56.3 22.2 1.2e-11 44.3 8.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EEQ32339.1 - 2.2e-14 53.9 1.7 7.9e-14 52.1 1.7 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EEQ32339.1 - 1e-07 32.1 0.1 2.2e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EEQ32339.1 - 0.026 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Uds1 PF15456.6 EEQ32339.1 - 2.7 8.2 5.7 1.2 9.3 0.9 2.4 2 0 0 2 2 2 0 Up-regulated During Septation TFIIA PF03153.13 EEQ32339.1 - 3.7 7.4 13.9 11 5.9 13.9 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFCD_C PF12612.8 EEQ32341.1 - 8.8e-40 136.6 0.2 3.7e-39 134.5 0.0 2.1 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EEQ32341.1 - 3.9e-05 23.6 0.0 1.5 9.3 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EEQ32341.1 - 0.00059 20.2 0.1 0.7 10.3 0.1 3.4 2 0 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 EEQ32341.1 - 0.00086 19.8 1.0 3.2 8.4 0.0 4.8 4 0 0 4 4 4 1 HEAT-like repeat IFRD PF05004.13 EEQ32341.1 - 0.021 14.0 0.4 0.17 11.0 0.2 2.5 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 EEQ32341.1 - 0.022 15.4 0.0 2.5 8.8 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region APH PF01636.23 EEQ32342.1 - 1.8e-10 41.1 0.0 4.4e-09 36.6 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ32342.1 - 0.052 12.4 0.0 0.62 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) H_lectin PF09458.10 EEQ32342.1 - 0.15 12.3 0.2 0.44 10.8 0.2 1.8 1 0 0 1 1 1 0 H-type lectin domain RRM_1 PF00076.22 EEQ32343.1 - 8e-27 92.9 0.5 2.9e-12 46.2 0.2 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ32343.1 - 0.00012 21.7 0.0 0.0026 17.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ32343.1 - 0.0033 17.3 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 EEQ32343.1 - 0.03 14.2 0.1 0.068 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) ATP-synt_D PF01813.17 EEQ32344.1 - 5.4e-71 238.5 1.7 7.6e-71 238.0 1.7 1.2 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.6 EEQ32344.1 - 0.0019 18.3 2.2 0.014 15.4 0.5 2.4 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 APG6_N PF17675.1 EEQ32344.1 - 0.027 15.0 0.6 0.027 15.0 0.6 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region HtrL_YibB PF09612.10 EEQ32344.1 - 0.05 13.1 0.3 0.077 12.5 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) DUF3919 PF13057.6 EEQ32344.1 - 0.076 12.6 1.1 0.11 12.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) DUF5446 PF17522.2 EEQ32344.1 - 0.63 10.2 2.3 0.79 9.9 0.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5446) TPR_14 PF13428.6 EEQ32345.1 - 2.5e-16 58.9 7.1 4.5 8.4 0.1 11.4 11 1 1 12 12 12 3 Tetratricopeptide repeat Suf PF05843.14 EEQ32345.1 - 4.7e-10 39.9 14.0 0.005 16.9 0.3 6.1 3 1 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EEQ32345.1 - 4.2e-08 32.8 5.6 0.4 11.0 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ32345.1 - 6e-08 33.1 0.0 1.7 9.2 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ32345.1 - 1.1e-06 28.8 4.7 24 5.3 0.0 7.2 6 1 0 6 6 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EEQ32345.1 - 3.2e-06 27.1 14.8 1.1 9.2 0.1 7.3 6 2 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EEQ32345.1 - 5.3e-06 26.1 11.5 1.1 9.6 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EEQ32345.1 - 5.5e-06 25.8 8.4 0.00012 21.5 0.2 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ32345.1 - 0.00056 20.1 3.3 0.37 11.3 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ32345.1 - 0.0014 18.4 0.0 3.9 7.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.16 EEQ32345.1 - 0.0063 16.4 3.1 2.1 8.4 0.1 5.4 5 0 0 5 5 4 1 HAT (Half-A-TPR) repeat ANAPC3 PF12895.7 EEQ32345.1 - 0.048 13.9 0.1 11 6.3 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 RGS PF00615.19 EEQ32345.1 - 0.11 12.8 0.7 1.6 9.0 0.2 2.9 2 0 0 2 2 2 0 Regulator of G protein signaling domain TPR_10 PF13374.6 EEQ32345.1 - 0.77 9.7 10.0 1e+02 3.0 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EEQ32345.1 - 0.82 8.7 17.1 0.015 14.4 1.2 5.6 4 3 0 4 4 4 0 NRDE-2, necessary for RNA interference Sec7 PF01369.20 EEQ32346.1 - 4.8e-60 202.4 0.0 7.5e-60 201.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EEQ32346.1 - 7.1e-21 74.8 0.1 8.3e-20 71.3 0.0 2.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EEQ32346.1 - 0.0035 17.0 0.6 0.0035 17.0 0.6 1.8 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 RhoGEF PF00621.20 EEQ32349.1 - 2.1e-19 70.4 0.0 5.1e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 EEQ32349.1 - 6.2e-05 22.8 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 EEQ32349.1 - 0.031 14.4 0.1 0.95 9.6 0.0 3.1 3 0 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 Gp58 PF07902.11 EEQ32349.1 - 0.14 10.4 0.9 0.3 9.3 0.2 1.7 1 1 1 2 2 2 0 gp58-like protein OmpH PF03938.14 EEQ32349.1 - 2.9 8.2 8.6 0.37 11.1 2.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ATP_bind_3 PF01171.20 EEQ32350.1 - 4.3e-41 140.7 0.0 1.5e-40 138.9 0.0 1.9 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 EEQ32350.1 - 0.16 11.1 0.0 0.45 9.6 0.0 1.7 2 0 0 2 2 2 0 NAD synthase Mito_carr PF00153.27 EEQ32351.1 - 4.7e-45 151.5 2.8 1.2e-19 70.0 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.8 EEQ32351.1 - 4.9e-36 124.2 0.1 9.6e-36 123.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EEQ32351.1 - 6.9e-20 71.0 15.9 3.2e-05 24.6 0.2 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ32351.1 - 0.016 15.5 0.1 0.21 11.9 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 EEQ32352.1 - 1.4e-46 159.0 0.0 8.4e-46 156.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32352.1 - 6.8e-21 74.7 0.0 1.1e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ32352.1 - 0.0044 17.0 0.5 0.0086 16.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ32352.1 - 0.014 14.7 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EEQ32352.1 - 0.024 13.6 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L11 PF00298.19 EEQ32353.1 - 2.4e-27 95.2 0.1 3.7e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EEQ32353.1 - 4.2e-26 90.6 0.3 7.3e-26 89.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1_C PF17187.4 EEQ32354.1 - 3.9e-57 192.6 0.0 7.1e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EEQ32354.1 - 1.1e-39 136.1 0.3 7.4e-21 74.9 0.0 2.3 1 1 1 2 2 2 2 Svf1-like N-terminal lipocalin domain MFMR PF07777.11 EEQ32354.1 - 0.039 14.5 1.1 0.76 10.3 0.0 3.4 3 1 0 3 3 3 0 G-box binding protein MFMR BP28CT PF08146.12 EEQ32355.1 - 0.048 13.5 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 BP28CT (NUC211) domain Acetyltransf_1 PF00583.25 EEQ32356.1 - 3.1e-05 24.2 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF5368 PF17336.2 EEQ32356.1 - 0.0019 18.3 2.2 0.0032 17.6 2.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5368) Acetyltransf_7 PF13508.7 EEQ32356.1 - 0.0032 17.8 0.0 0.0062 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ32356.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_6 PF12774.7 EEQ32358.1 - 5.3e-124 413.5 0.0 1.9e-123 411.6 0.0 2.1 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EEQ32358.1 - 9.2e-123 410.8 7.5 9.2e-123 410.8 7.5 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EEQ32358.1 - 6.3e-112 374.6 2.6 6.3e-112 374.6 2.6 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EEQ32358.1 - 2.9e-74 248.9 1.5 2.9e-74 248.9 1.5 3.1 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 EEQ32358.1 - 1e-44 152.8 0.1 1.4e-29 103.2 0.0 3.5 2 1 1 3 3 3 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EEQ32358.1 - 7.5e-42 142.9 0.0 2.1e-36 125.1 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EEQ32358.1 - 2.8e-32 112.1 0.8 5.3e-32 111.2 0.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EEQ32358.1 - 3.8e-31 107.7 0.1 2.5e-26 92.1 0.0 4.6 5 0 0 5 5 4 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EEQ32358.1 - 1.6e-28 99.4 0.1 5.8e-11 42.6 0.0 5.8 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 EEQ32358.1 - 3e-27 95.4 0.0 8.8e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 EEQ32358.1 - 1.7e-18 67.0 0.1 1.8e-16 60.4 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 EEQ32358.1 - 3e-14 53.6 0.0 0.00046 20.6 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ32358.1 - 7.4e-14 52.2 6.9 0.008 16.5 0.0 7.3 8 0 0 8 8 6 2 AAA domain AAA_16 PF13191.6 EEQ32358.1 - 5.8e-10 39.8 0.4 1.2 9.5 0.0 7.2 7 0 0 7 7 6 2 AAA ATPase domain AAA_18 PF13238.6 EEQ32358.1 - 6.5e-10 39.7 1.2 0.093 13.3 0.0 5.6 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.6 EEQ32358.1 - 2.9e-09 37.2 6.0 0.048 13.8 0.0 5.5 6 0 0 6 6 5 3 AAA domain AAA_lid_1 PF17857.1 EEQ32358.1 - 2.8e-06 27.5 2.9 6e-05 23.2 0.0 3.6 4 0 0 4 4 2 1 AAA+ lid domain T2SSE PF00437.20 EEQ32358.1 - 9e-06 24.9 0.0 0.033 13.2 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EEQ32358.1 - 3.5e-05 23.3 0.7 0.65 9.3 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EEQ32358.1 - 5.1e-05 23.8 0.1 3.3 8.2 0.0 4.7 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 EEQ32358.1 - 9.8e-05 22.0 0.1 2.2 8.1 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EEQ32358.1 - 0.00014 21.3 0.0 2 7.7 0.0 3.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_14 PF13173.6 EEQ32358.1 - 0.00017 21.6 0.0 1.8 8.6 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 EEQ32358.1 - 0.00026 21.3 1.0 0.27 11.6 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 EEQ32358.1 - 0.00069 19.4 0.3 37 3.9 0.0 4.5 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 EEQ32358.1 - 0.0038 17.0 0.7 11 5.7 0.0 4.1 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 EEQ32358.1 - 0.004 16.9 0.7 0.6 9.8 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.6 EEQ32358.1 - 0.004 16.7 0.0 0.32 10.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EEQ32358.1 - 0.0083 15.4 0.2 5.7 6.2 0.1 4.1 4 0 0 4 4 4 0 Zeta toxin BRE1 PF08647.11 EEQ32358.1 - 0.0094 16.0 1.4 0.12 12.5 1.4 3.0 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase TrwB_AAD_bind PF10412.9 EEQ32358.1 - 0.011 14.7 0.1 4.2 6.2 0.0 3.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 EEQ32358.1 - 0.016 15.6 0.8 22 5.5 0.0 4.5 5 0 0 5 5 4 0 RNA helicase Rad17 PF03215.15 EEQ32358.1 - 0.016 15.1 0.1 6.4 6.7 0.0 3.9 4 0 0 4 4 3 0 Rad17 P-loop domain MEDS PF14417.6 EEQ32358.1 - 0.026 14.3 0.6 0.16 11.8 0.2 2.7 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA_21 PF13304.6 EEQ32358.1 - 0.09 12.6 0.5 8.5 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3867 PF12983.7 EEQ32358.1 - 4 7.4 6.1 0.91 9.5 0.7 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3867) NACHT PF05729.12 EEQ32358.1 - 5 7.0 7.3 31 4.5 0.0 4.1 4 0 0 4 4 3 0 NACHT domain Pil1 PF13805.6 EEQ32358.1 - 5.2 6.5 12.1 0.019 14.5 0.9 2.3 2 0 0 2 2 1 0 Eisosome component PIL1 Ribonuclease_3 PF00636.26 EEQ32359.1 - 2.3e-39 134.2 0.0 2.6e-18 66.6 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EEQ32359.1 - 5.5e-21 75.1 0.0 2.3e-11 43.9 0.0 3.3 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 EEQ32359.1 - 1e-19 70.5 0.1 1.5e-18 66.7 0.1 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.15 EEQ32359.1 - 2.3e-15 57.0 0.1 6.2e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ32359.1 - 4.1e-14 52.9 0.2 1.7e-13 50.9 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ32359.1 - 2.7e-10 40.3 0.0 5.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 EEQ32359.1 - 0.018 15.7 0.3 4.4 8.1 0.1 3.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif AAA_22 PF13401.6 EEQ32359.1 - 0.046 14.0 0.1 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EEQ32359.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TAP42 PF04177.12 EEQ32360.1 - 2e-107 359.1 0.9 2.2e-107 358.9 0.9 1.0 1 0 0 1 1 1 1 TAP42-like family DUF725 PF05267.12 EEQ32360.1 - 0.11 12.5 0.4 0.21 11.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) PilJ PF13675.6 EEQ32360.1 - 0.15 12.1 1.8 3.2 7.8 0.2 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term HisKA PF00512.25 EEQ32360.1 - 0.21 11.6 1.0 28 4.8 0.0 2.8 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Lipase_GDSL PF00657.22 EEQ32361.1 - 6.4e-09 36.1 0.0 8.3e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EEQ32361.1 - 2.4e-05 24.8 0.1 0.00052 20.5 0.1 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Porphobil_deam PF01379.20 EEQ32362.1 - 1.7e-72 243.2 0.0 2.3e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EEQ32362.1 - 1.7e-18 66.8 0.3 2.9e-18 66.0 0.3 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.13 EEQ32363.1 - 1.7e-68 230.2 0.2 3.5e-68 229.2 0.2 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EEQ32363.1 - 6.6e-25 88.2 0.1 1.7e-24 86.9 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EEQ32363.1 - 2.7e-24 86.1 0.0 2.1e-23 83.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EEQ32363.1 - 9e-08 32.0 0.0 1.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EEQ32363.1 - 1.5e-07 31.5 0.0 4.1e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEQ32363.1 - 1.6e-06 28.6 0.0 1e-05 26.0 0.0 2.4 2 0 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EEQ32363.1 - 7.3e-06 25.8 0.0 2.1e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EEQ32363.1 - 2e-05 23.9 0.0 4.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 EEQ32363.1 - 4e-05 23.5 0.0 0.00014 21.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EEQ32363.1 - 0.00038 20.6 0.0 0.0012 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EEQ32363.1 - 0.00041 20.1 0.1 0.0012 18.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ32363.1 - 0.00072 19.8 0.0 0.0097 16.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ32363.1 - 0.0066 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EEQ32363.1 - 0.013 15.6 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEQ32363.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EEQ32363.1 - 0.022 15.1 0.0 0.059 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EEQ32363.1 - 0.025 14.0 0.1 0.059 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EEQ32363.1 - 0.03 14.3 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 EEQ32363.1 - 0.031 14.8 0.0 0.084 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ32363.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 EEQ32363.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein TniB PF05621.11 EEQ32363.1 - 0.049 13.0 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 1 0 Bacterial TniB protein TsaE PF02367.17 EEQ32363.1 - 0.05 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_PrkA PF08298.11 EEQ32363.1 - 0.05 12.5 0.1 0.23 10.3 0.1 1.9 1 1 1 2 2 2 0 PrkA AAA domain AAA_25 PF13481.6 EEQ32363.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EEQ32363.1 - 0.065 13.1 0.2 3.2 7.6 0.0 3.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EEQ32363.1 - 0.072 12.9 0.1 0.072 12.9 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 EEQ32363.1 - 0.087 13.2 0.1 0.3 11.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EEQ32363.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EEQ32363.1 - 0.13 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 EEQ32363.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EEQ32363.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EEQ32363.1 - 0.16 12.5 0.1 0.16 12.5 0.1 2.9 1 1 2 3 3 2 0 AAA domain ABC_tran PF00005.27 EEQ32363.1 - 0.27 11.8 0.1 0.27 11.8 0.1 2.7 1 1 1 2 2 2 0 ABC transporter Laps PF10169.9 EEQ32363.1 - 1.4 9.5 4.1 4.5 7.9 0.1 2.4 1 1 1 2 2 2 0 Learning-associated protein Ribosomal_L23 PF00276.20 EEQ32364.1 - 5e-10 39.6 0.0 8.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.22 EEQ32365.1 - 4e-41 140.7 0.3 7.2e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 EEQ32365.1 - 4.3e-32 110.2 0.0 1.1e-31 108.9 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EEQ32365.1 - 2.5e-06 27.6 0.0 0.013 15.5 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEQ32365.1 - 1.1e-05 24.8 0.0 0.00057 19.3 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.14 EEQ32365.1 - 5.6 5.1 8.2 9.9 4.3 8.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Chs7 PF12271.8 EEQ32366.1 - 6.2e-124 413.0 14.0 7.1e-124 412.8 14.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Ribosomal_L27A PF00828.19 EEQ32367.1 - 1.7e-30 106.4 0.5 2.6e-30 105.7 0.5 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF846 PF05832.12 EEQ32368.1 - 0.2 11.7 0.2 0.26 11.3 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Pkinase PF00069.25 EEQ32369.1 - 2.3e-47 161.6 0.0 3e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32369.1 - 3.4e-28 98.7 0.0 1.5e-26 93.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ32369.1 - 0.0043 15.9 0.0 0.0071 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Chorion_2 PF03964.15 EEQ32369.1 - 0.014 16.3 1.6 0.014 16.3 1.6 3.2 2 1 0 3 3 3 0 Chorion family 2 SH3_1 PF00018.28 EEQ32370.1 - 1.7e-05 24.3 0.0 3.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ32370.1 - 0.0045 16.8 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_16 PF18348.1 EEQ32370.1 - 0.034 14.0 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain SH3_3 PF08239.11 EEQ32370.1 - 0.098 12.9 0.1 0.88 9.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain SH3_2 PF07653.17 EEQ32370.1 - 0.11 12.2 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Variant SH3 domain RCC1_2 PF13540.6 EEQ32371.1 - 3.1e-15 55.5 5.4 5.3e-08 32.5 0.0 5.2 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EEQ32371.1 - 1.1e-07 31.7 0.1 2.1e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ32371.1 - 0.011 15.6 0.2 0.028 14.3 0.2 1.7 1 0 0 1 1 1 0 F-box domain RCC1 PF00415.18 EEQ32371.1 - 0.012 16.2 0.0 2.4 8.9 0.0 4.0 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat PQ-loop PF04193.14 EEQ32372.1 - 9.8e-37 124.5 17.1 2.5e-19 68.8 1.8 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 EEQ32372.1 - 0.0017 18.4 4.6 0.011 15.8 0.1 2.7 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange 7TM_GPCR_Srsx PF10320.9 EEQ32372.1 - 0.0099 15.3 1.2 0.018 14.4 1.2 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2627 PF11118.8 EEQ32372.1 - 0.068 13.8 0.4 6 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Aminotran_1_2 PF00155.21 EEQ32375.1 - 4.8e-42 144.4 0.0 1.2e-35 123.3 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II PT PF04886.12 EEQ32375.1 - 1.2 8.7 5.7 2.1 8.0 1.1 2.6 2 0 0 2 2 2 0 PT repeat AMP-binding PF00501.28 EEQ32376.1 - 1.6e-34 119.2 0.0 7.2e-34 117.1 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EEQ32376.1 - 4.5e-10 39.3 1.0 2.2e-09 37.1 0.1 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Peptidase_M16_C PF05193.21 EEQ32377.1 - 1.3e-48 165.4 0.0 5.9e-48 163.3 0.0 2.1 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EEQ32377.1 - 1.2e-40 138.9 0.0 2.2e-39 134.8 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) TRPM_tetra PF16519.5 EEQ32377.1 - 0.18 11.9 1.0 0.57 10.3 1.0 1.8 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Abhydrolase_2 PF02230.16 EEQ32378.1 - 7.7e-25 88.0 0.0 3.1e-17 63.1 0.0 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EEQ32378.1 - 0.00019 20.8 0.0 0.0051 16.1 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EEQ32378.1 - 0.0015 18.0 0.0 0.0043 16.5 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EEQ32378.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tom22 PF04281.13 EEQ32379.1 - 6e-52 175.1 0.8 7e-52 174.9 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.6 EEQ32380.1 - 1.5e-38 132.1 0.0 2.9e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DUF4449 PF14613.6 EEQ32381.1 - 6e-64 215.1 1.9 6e-64 215.1 1.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Ribosomal_L36e PF01158.18 EEQ32381.1 - 0.62 10.3 5.5 0.37 11.1 0.8 2.7 2 0 0 2 2 2 0 Ribosomal protein L36e Prp18 PF02840.15 EEQ32381.1 - 1.7 8.7 7.5 18 5.4 0.3 4.1 3 1 1 4 4 4 0 Prp18 domain Peptidase_M35 PF02102.15 EEQ32382.1 - 9.9e-94 314.1 7.0 1.2e-93 313.8 7.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EEQ32382.1 - 1.7e-43 148.6 0.9 3.2e-43 147.8 0.9 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EEQ32382.1 - 0.00013 21.6 0.5 0.00032 20.3 0.5 1.6 1 1 0 1 1 1 1 Putative peptidase family Lipoprotein_9 PF03180.14 EEQ32382.1 - 0.047 12.8 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 NLPA lipoprotein Period_C PF12114.8 EEQ32382.1 - 0.22 11.1 2.6 0.3 10.7 1.7 1.5 1 1 0 1 1 1 0 Period protein 2/3C-terminal region vWA-TerF-like PF10138.9 EEQ32385.1 - 2.8e-07 30.9 0.0 4.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro-rich PF15240.6 EEQ32385.1 - 0.0011 19.3 30.8 0.0011 19.3 30.8 2.4 2 0 0 2 2 2 2 Proline-rich VWA PF00092.28 EEQ32385.1 - 0.012 15.9 0.1 0.025 14.8 0.1 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain Lin-8 PF03353.15 EEQ32385.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PhoLip_ATPase_C PF16212.5 EEQ32386.1 - 6.1e-72 242.4 19.9 6.1e-72 242.4 19.9 2.6 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEQ32386.1 - 1.9e-25 88.3 2.3 7.8e-24 83.2 0.2 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EEQ32386.1 - 1.9e-15 57.8 0.3 1.6e-05 25.3 0.1 3.4 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEQ32386.1 - 1.2e-13 50.9 0.1 1.2e-13 50.9 0.1 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EEQ32386.1 - 4.3e-12 45.9 0.0 3.2e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEQ32386.1 - 0.0022 17.8 0.1 0.0077 16.0 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ32386.1 - 0.11 12.6 0.2 0.4 10.7 0.1 1.9 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 EEQ32387.1 - 4.2e-20 71.3 3.3 9.9e-20 70.2 3.3 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EEQ32387.1 - 0.0012 18.7 0.6 0.003 17.4 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain NAM-associated PF14303.6 EEQ32387.1 - 0.34 11.6 5.9 0.65 10.7 5.9 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PGP_phosphatase PF09419.10 EEQ32388.1 - 8.5e-48 162.1 0.0 9.9e-48 161.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EEQ32388.1 - 3.8e-06 26.9 0.0 6.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EEQ32388.1 - 0.015 15.6 0.0 4.7 7.4 0.0 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase LSM PF01423.22 EEQ32389.1 - 9.3e-15 54.1 0.2 1.2e-14 53.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain Adaptin_binding PF10199.9 EEQ32390.1 - 7.8e-18 65.2 0.6 6.2e-17 62.3 0.9 2.0 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 PTPLA PF04387.14 EEQ32391.1 - 8.1e-31 107.0 0.5 1.3e-30 106.4 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SRP_TPR_like PF17004.5 EEQ32392.1 - 2.1e-17 63.2 0.8 1.1e-16 60.9 0.2 2.3 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 EEQ32392.1 - 2.1e-11 44.1 3.6 2.1e-11 44.1 3.6 2.1 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 EEQ32392.1 - 5.8e-10 39.5 0.5 0.51 10.9 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ32392.1 - 0.00026 20.9 8.5 0.27 11.4 0.5 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat SPO22 PF08631.10 EEQ32392.1 - 0.017 14.6 0.4 0.044 13.3 0.4 1.7 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_4 PF07721.14 EEQ32392.1 - 0.065 13.9 0.0 84 4.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EEQ32392.1 - 0.081 13.3 0.2 16 5.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ32392.1 - 0.2 11.9 6.8 14 6.0 0.0 5.2 5 2 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Homeobox_KN PF05920.11 EEQ32393.1 - 6.9e-20 70.7 0.8 6.9e-20 70.7 0.8 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EEQ32393.1 - 0.00012 21.8 0.2 0.00023 21.0 0.2 1.5 1 0 0 1 1 1 1 Homeodomain FAD_binding_1 PF00667.20 EEQ32396.1 - 6.4e-40 137.1 0.0 1e-39 136.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EEQ32396.1 - 4.4e-09 37.0 0.0 1e-08 35.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ABC_membrane PF00664.23 EEQ32397.1 - 8.1e-100 334.0 33.7 5e-52 177.2 9.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ32397.1 - 2.2e-53 180.5 0.0 3.5e-33 115.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ32397.1 - 8.6e-12 45.0 1.0 1.4e-05 24.7 0.0 3.6 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EEQ32397.1 - 1.7e-08 35.0 3.7 0.0003 21.2 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain AAA_15 PF13175.6 EEQ32397.1 - 3.3e-07 30.3 0.0 0.0039 16.9 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EEQ32397.1 - 7.7e-07 28.8 0.6 0.043 13.6 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ32397.1 - 2.2e-06 27.7 0.0 0.079 12.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EEQ32397.1 - 4.8e-06 26.9 0.2 0.042 14.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EEQ32397.1 - 8.3e-06 25.8 0.0 0.067 13.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EEQ32397.1 - 1.2e-05 25.1 0.1 0.98 9.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EEQ32397.1 - 2.5e-05 24.8 0.6 0.087 13.3 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EEQ32397.1 - 8.2e-05 23.0 0.1 2.3 8.6 0.1 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EEQ32397.1 - 0.00034 20.0 0.1 2 7.6 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin AAA_7 PF12775.7 EEQ32397.1 - 0.00039 20.0 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 EEQ32397.1 - 0.0035 17.4 0.0 4.1 7.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EEQ32397.1 - 0.0037 17.2 0.0 0.04 13.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 EEQ32397.1 - 0.0052 17.0 0.1 1.2 9.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EEQ32397.1 - 0.0099 15.5 0.2 2.7 7.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 EEQ32397.1 - 0.017 15.2 1.5 0.097 12.8 0.1 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_ATPase PF09818.9 EEQ32397.1 - 0.022 13.6 0.0 0.059 12.2 0.1 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class APS_kinase PF01583.20 EEQ32397.1 - 0.023 14.6 0.0 4 7.3 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_18 PF13238.6 EEQ32397.1 - 0.031 14.8 0.0 4.2 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EEQ32397.1 - 0.076 12.7 0.1 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MinC_C PF03775.16 EEQ32397.1 - 0.093 12.7 0.1 3.6 7.6 0.1 2.6 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain RNA_helicase PF00910.22 EEQ32397.1 - 0.11 12.8 0.0 4.7 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 EEQ32397.1 - 0.12 12.5 0.1 1.2e+02 2.6 0.0 3.8 4 0 0 4 4 4 0 Dynamin family NB-ARC PF00931.22 EEQ32397.1 - 0.13 11.4 0.0 5.2 6.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 EEQ32397.1 - 0.16 12.0 0.6 13 5.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EEQ32397.1 - 0.18 12.0 0.4 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhyH PF05721.13 EEQ32398.1 - 1e-19 71.6 0.4 1.4e-19 71.2 0.4 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Med20 PF08612.11 EEQ32399.1 - 3.4e-59 199.9 0.0 4.3e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex GDE_N_bis PF14742.6 EEQ32399.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes EF-hand_8 PF13833.6 EEQ32400.1 - 3.7e-29 100.3 3.5 7.6e-12 44.9 0.1 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EEQ32400.1 - 2e-26 89.5 7.5 2e-09 36.3 0.0 3.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EEQ32400.1 - 3.8e-23 81.7 2.9 7.2e-14 52.0 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EEQ32400.1 - 5.5e-17 60.2 2.7 6e-09 35.1 0.0 3.9 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EEQ32400.1 - 3.3e-16 58.0 5.4 7.6e-06 25.2 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EEQ32400.1 - 3.1e-09 37.0 0.2 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 EEQ32400.1 - 3.3e-05 23.8 0.1 0.063 13.3 0.1 2.8 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 EEQ32400.1 - 0.00019 21.4 0.7 0.35 10.8 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand RNA_pol_Rpb4 PF03874.16 EEQ32400.1 - 0.0003 21.1 0.5 0.23 11.8 0.2 2.6 2 1 0 2 2 2 2 RNA polymerase Rpb4 SPARC_Ca_bdg PF10591.9 EEQ32400.1 - 0.00074 19.8 0.2 0.072 13.4 0.1 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 EEQ32400.1 - 0.0018 18.3 0.1 0.0046 17.0 0.0 1.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EEQ32400.1 - 0.038 14.9 0.1 0.41 11.5 0.1 1.9 1 1 1 2 2 2 0 EF-hand domain RuvA_C PF07499.13 EEQ32400.1 - 0.05 14.1 0.0 8.5 6.9 0.0 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain Poly_export PF02563.16 EEQ32400.1 - 0.068 13.4 0.0 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 EEQ32400.1 - 0.086 12.7 0.3 2.2 8.2 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain DUF5132 PF17195.4 EEQ32400.1 - 0.13 12.4 0.3 15 5.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Dockerin_1 PF00404.18 EEQ32400.1 - 0.57 10.4 5.5 2 8.7 1.0 2.7 1 1 2 3 3 3 0 Dockerin type I domain SNARE PF05739.19 EEQ32401.1 - 6.8e-15 54.8 0.9 1.3e-14 53.9 0.9 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EEQ32401.1 - 0.012 15.3 9.2 0.062 13.0 9.2 1.9 1 1 0 1 1 1 0 Syntaxin HlyD_D4 PF16572.5 EEQ32401.1 - 0.044 13.7 0.1 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB MCPsignal PF00015.21 EEQ32401.1 - 0.53 10.1 5.7 0.47 10.2 0.5 2.5 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CTD_bind PF04818.13 EEQ32402.1 - 7.3e-06 26.7 3.3 0.00071 20.4 2.4 3.1 2 1 0 2 2 2 1 RNA polymerase II-binding domain. YscO-like PF16789.5 EEQ32402.1 - 0.023 14.7 1.7 0.059 13.4 1.7 1.6 1 0 0 1 1 1 0 YscO-like protein Spc7 PF08317.11 EEQ32402.1 - 0.029 13.2 0.6 0.029 13.2 0.6 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Mt_ATP-synt_D PF05873.12 EEQ32402.1 - 0.042 13.7 0.2 0.56 10.1 0.0 2.6 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DnaG_DnaB_bind PF08278.11 EEQ32402.1 - 0.21 12.2 2.9 0.52 10.9 0.6 2.3 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Clathrin_lg_ch PF01086.17 EEQ32403.1 - 3.3e-74 249.8 4.2 3.7e-74 249.7 4.2 1.0 1 0 0 1 1 1 1 Clathrin light chain LpqV PF17301.2 EEQ32403.1 - 0.029 14.6 0.6 0.054 13.7 0.3 1.6 1 1 0 1 1 1 0 Putative lipoprotein LpqV Acyl_transf_3 PF01757.22 EEQ32404.1 - 4.9e-23 81.7 30.9 7.2e-23 81.2 30.9 1.3 1 0 0 1 1 1 1 Acyltransferase family Mannosyl_trans3 PF11051.8 EEQ32405.1 - 2.3e-55 187.9 0.0 1.1e-33 116.8 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative CDC37_N PF03234.14 EEQ32407.1 - 1e-50 172.0 9.5 1.7e-50 171.2 1.9 3.1 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EEQ32407.1 - 3.1e-40 136.8 0.4 7.7e-40 135.5 0.1 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EEQ32407.1 - 1.9e-34 117.7 0.5 1.9e-34 117.7 0.5 2.2 2 1 0 2 2 2 1 Cdc37 C terminal domain MecA_N PF05223.11 EEQ32407.1 - 0.0038 17.5 1.5 0.008 16.4 0.4 2.1 2 0 0 2 2 2 1 NTF2-like N-terminal transpeptidase domain Thiamine_BP PF01910.17 EEQ32407.1 - 0.15 12.0 0.2 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Thiamine-binding protein DUF3552 PF12072.8 EEQ32407.1 - 0.24 10.8 4.5 0.18 11.2 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) ABC_membrane PF00664.23 EEQ32408.1 - 6.1e-53 180.2 11.5 7.9e-53 179.9 11.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ32408.1 - 3.7e-35 121.4 0.1 1.2e-34 119.8 0.0 1.9 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 EEQ32408.1 - 4.2e-07 29.6 0.1 3.6e-05 23.3 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EEQ32408.1 - 0.00015 22.2 1.1 0.00051 20.5 0.1 2.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EEQ32408.1 - 0.0031 17.8 0.2 0.021 15.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EEQ32408.1 - 0.0056 16.4 0.3 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EEQ32408.1 - 0.023 14.4 0.0 0.073 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EEQ32408.1 - 0.024 15.1 0.0 0.12 12.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EEQ32408.1 - 0.026 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EEQ32408.1 - 0.033 13.9 0.2 0.48 10.1 0.0 2.4 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 EEQ32408.1 - 0.064 12.8 0.0 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EEQ32408.1 - 0.09 13.3 1.2 0.71 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EEQ32408.1 - 0.12 12.4 0.1 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EEQ32408.1 - 0.15 12.3 0.8 2.5 8.4 0.6 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Nucleoside_tran PF01733.18 EEQ32409.1 - 2.2e-41 142.2 11.6 3.6e-39 135.0 11.6 2.3 1 1 0 1 1 1 1 Nucleoside transporter DUF2070 PF09843.9 EEQ32409.1 - 0.29 9.4 15.0 0.74 8.0 6.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) zf-C2H2 PF00096.26 EEQ32410.1 - 1.9e-06 28.0 6.1 0.0045 17.4 0.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ32410.1 - 0.00019 22.0 6.5 0.22 12.4 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EEQ32410.1 - 0.00026 21.7 0.5 0.027 15.2 0.0 2.2 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 EEQ32410.1 - 0.0061 16.2 0.4 0.95 9.2 0.0 2.3 2 0 0 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 EEQ32410.1 - 0.079 13.3 1.1 14 6.1 0.0 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 EEQ32410.1 - 4.8 7.8 7.1 14 6.3 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Metallophos_2 PF12850.7 EEQ32411.1 - 1.2e-09 38.5 0.0 1.6e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EEQ32411.1 - 2.7e-09 37.8 0.0 3.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Haspin_kinase PF12330.8 EEQ32412.1 - 3.8e-43 147.8 0.0 5.6e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EEQ32412.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1682 PF07946.14 EEQ32414.1 - 3.2e-113 378.2 0.7 3.7e-113 378.0 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) PPR_3 PF13812.6 EEQ32415.1 - 0.00044 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Pentatricopeptide repeat domain DUF1658 PF07871.11 EEQ32415.1 - 0.047 13.6 0.2 0.18 11.8 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) SYF2 PF08231.12 EEQ32417.1 - 1e-55 188.5 17.7 1e-55 188.5 17.7 2.0 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.14 EEQ32417.1 - 0.14 12.3 0.4 0.14 12.3 0.4 3.5 1 1 1 3 3 3 0 ARD/ARD' family DUF1797 PF08796.10 EEQ32417.1 - 4.4 7.5 6.0 0.64 10.1 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) NAD_binding_10 PF13460.6 EEQ32418.1 - 5.3e-07 29.7 0.0 2.1e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EEQ32418.1 - 2.3e-05 24.0 0.0 7.5e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ32418.1 - 0.00033 19.8 0.0 0.0011 18.1 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EEQ32418.1 - 0.0016 18.0 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EEQ32418.1 - 0.021 13.9 0.0 0.081 12.0 0.0 1.9 3 0 0 3 3 3 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EEQ32418.1 - 0.024 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EEQ32418.1 - 0.04 13.1 0.1 1.8 7.6 0.0 2.9 2 1 0 2 2 2 0 Male sterility protein Pox_RNA_Pol_19 PF05320.12 EEQ32418.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit YEATS PF03366.16 EEQ32419.1 - 1.2e-36 124.5 0.7 1.9e-36 123.9 0.7 1.3 1 0 0 1 1 1 1 YEATS family YebG PF07130.12 EEQ32419.1 - 0.051 13.4 0.2 0.17 11.7 0.2 1.8 2 0 0 2 2 2 0 YebG protein Rep_fac_C PF08542.11 EEQ32420.1 - 1.3e-23 83.2 0.1 4.6e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EEQ32420.1 - 6.1e-12 45.6 0.0 1e-08 35.1 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EEQ32420.1 - 3.3e-11 43.7 0.0 5.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EEQ32420.1 - 1.1e-06 28.7 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEQ32420.1 - 3.3e-06 27.6 0.0 0.00017 22.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EEQ32420.1 - 2.7e-05 24.0 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EEQ32420.1 - 5.3e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ32420.1 - 0.00012 22.4 0.1 0.14 12.4 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 EEQ32420.1 - 0.00023 21.0 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EEQ32420.1 - 0.00058 19.7 0.0 0.00094 19.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EEQ32420.1 - 0.0023 17.3 0.0 0.023 14.1 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 EEQ32420.1 - 0.0055 17.0 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain Rad17 PF03215.15 EEQ32420.1 - 0.0068 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain MeaB PF03308.16 EEQ32420.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EEQ32420.1 - 0.0068 16.1 0.0 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEQ32420.1 - 0.016 15.5 0.1 0.042 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EEQ32420.1 - 0.018 14.8 0.1 0.92 9.3 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.6 EEQ32420.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EEQ32420.1 - 0.024 14.6 0.2 0.08 12.9 0.1 1.9 1 1 1 2 2 2 0 NTPase TniB PF05621.11 EEQ32420.1 - 0.03 13.8 0.0 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein KTI12 PF08433.10 EEQ32420.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 EEQ32420.1 - 0.11 12.2 0.1 0.37 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain His_Phos_2 PF00328.22 EEQ32421.1 - 2e-05 24.1 0.0 0.002 17.5 0.0 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF1338 PF07063.13 EEQ32422.1 - 2.2e-108 362.3 0.0 2.7e-108 362.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Dicty_REP PF05086.12 EEQ32423.1 - 0.49 8.3 0.6 0.48 8.3 0.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4106 PF13388.6 EEQ32423.1 - 1.8 7.7 6.1 2.3 7.4 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF410 PF04190.13 EEQ32424.1 - 8.3e-86 287.9 0.0 9.9e-86 287.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.11 EEQ32425.1 - 5.4e-28 97.0 0.1 1.5e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease CEP76-C2 PF15627.6 EEQ32425.1 - 0.0093 15.5 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 CEP76 C2 domain IPPT PF01715.17 EEQ32426.1 - 5.4e-61 206.3 0.2 8.3e-61 205.7 0.2 1.2 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 EEQ32426.1 - 7.3e-05 23.0 0.0 0.14 12.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain IPT PF01745.16 EEQ32426.1 - 0.00029 20.3 0.0 0.00068 19.1 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase zf-met PF12874.7 EEQ32426.1 - 0.00067 20.0 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_18 PF13238.6 EEQ32426.1 - 0.0021 18.6 0.5 0.84 10.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain zf-C2H2_2 PF12756.7 EEQ32426.1 - 0.013 15.8 0.4 0.065 13.6 0.0 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA_25 PF13481.6 EEQ32426.1 - 0.041 13.4 1.0 0.1 12.2 0.1 2.0 3 0 0 3 3 3 0 AAA domain CTU2 PF10288.9 EEQ32426.1 - 0.076 13.3 0.6 0.15 12.4 0.1 1.8 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 VASP_tetra PF08776.11 EEQ32426.1 - 0.082 12.5 0.5 0.29 10.7 0.0 2.2 2 0 0 2 2 2 0 VASP tetramerisation domain AAA_22 PF13401.6 EEQ32426.1 - 0.12 12.7 0.1 0.71 10.1 0.1 2.3 1 1 1 2 2 2 0 AAA domain zf-C2H2_jaz PF12171.8 EEQ32426.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 EEQ32426.1 - 0.18 11.7 1.5 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) ABC_tran PF00005.27 EEQ32427.1 - 1.4e-17 64.5 0.2 7.5e-17 62.1 0.2 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EEQ32427.1 - 1.1e-10 41.9 1.9 9.3e-05 22.4 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ32427.1 - 7.9e-05 22.2 0.1 0.21 11.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ32427.1 - 9.1e-05 22.1 0.3 0.00022 20.9 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EEQ32427.1 - 0.00087 19.1 0.1 0.0013 18.5 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EEQ32427.1 - 0.0033 18.0 0.0 0.0049 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EEQ32427.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EEQ32427.1 - 0.032 14.6 0.7 0.067 13.6 0.7 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 EEQ32427.1 - 0.032 14.3 0.1 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain DUF3584 PF12128.8 EEQ32427.1 - 0.034 11.7 0.1 0.044 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_25 PF13481.6 EEQ32427.1 - 0.034 13.7 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EEQ32427.1 - 0.051 12.5 0.0 0.25 10.2 0.0 1.9 1 1 1 2 2 2 0 AAA-like domain Dynamin_N PF00350.23 EEQ32427.1 - 0.064 13.3 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Dynamin family AAA_28 PF13521.6 EEQ32427.1 - 0.068 13.4 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EEQ32427.1 - 0.082 13.0 0.4 0.16 12.1 0.4 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_27 PF13514.6 EEQ32427.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EEQ32427.1 - 0.097 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EEQ32427.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.9 EEQ32427.1 - 0.26 11.0 0.0 0.4 10.4 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.32 EEQ32428.1 - 4.9e-32 109.5 26.1 1.3e-05 25.8 0.0 12.8 13 0 0 13 13 13 9 WD domain, G-beta repeat Urm1 PF09138.11 EEQ32429.1 - 2.2e-34 117.7 0.0 2.6e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EEQ32429.1 - 0.045 14.4 0.0 0.067 13.8 0.0 1.3 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.18 EEQ32430.1 - 1.4e-61 207.6 0.0 2.2e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EEQ32430.1 - 4.3e-19 69.0 0.0 1.8e-18 67.0 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EEQ32430.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Porin_3 PF01459.22 EEQ32431.1 - 1.1e-81 274.2 0.1 1.3e-81 274.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 EEQ32431.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.25 EEQ32432.1 - 2e-64 217.5 0.0 2.4e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32432.1 - 5.1e-24 84.9 0.0 7e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ32432.1 - 2.8e-06 26.9 0.0 8.6e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EEQ32432.1 - 0.0022 18.0 0.1 0.021 14.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family MIF4G_like PF09088.11 EEQ32433.1 - 1.3e-87 292.5 0.1 2.9e-87 291.4 0.1 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EEQ32433.1 - 1.2e-66 225.0 0.0 1.2e-66 225.0 0.0 1.7 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 EEQ32433.1 - 0.11 12.1 0.1 0.58 9.8 0.0 2.2 3 0 0 3 3 3 0 MIF4G domain FA_hydroxylase PF04116.13 EEQ32434.1 - 3.6e-25 88.8 15.2 3.6e-25 88.8 15.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily WD40 PF00400.32 EEQ32435.1 - 2.5e-58 192.7 15.8 4.2e-09 36.9 0.7 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EEQ32435.1 - 1.2e-18 67.1 9.3 2.1e-18 66.4 9.3 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EEQ32435.1 - 1.3e-15 57.5 0.0 0.0059 16.9 0.0 6.7 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EEQ32435.1 - 9.5e-08 31.7 0.0 0.064 12.6 0.0 4.2 2 1 2 4 4 4 3 WD40-like domain Cytochrom_D1 PF02239.16 EEQ32435.1 - 1.2e-05 24.0 0.5 0.00015 20.4 0.2 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EEQ32435.1 - 2.1e-05 23.6 0.2 0.84 8.5 0.0 4.6 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEQ32435.1 - 6.7e-05 21.7 0.1 0.25 9.9 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EEQ32435.1 - 0.0012 18.8 0.0 0.07 13.0 0.0 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A MMS1_N PF10433.9 EEQ32435.1 - 0.013 14.2 0.0 2.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nbas_N PF15492.6 EEQ32435.1 - 0.019 14.3 0.0 6.6 6.0 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EEQ32435.1 - 0.022 14.7 0.0 20 5.3 0.0 4.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TPX2 PF06886.11 EEQ32435.1 - 5.2 7.4 6.8 11 6.3 6.8 1.6 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) zf-C2H2 PF00096.26 EEQ32437.1 - 3.3e-17 61.9 23.3 0.00013 22.2 0.9 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ32437.1 - 6.4e-15 54.8 22.4 1.6e-07 31.4 2.2 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ32437.1 - 2.9e-09 37.0 22.7 0.046 14.6 0.6 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EEQ32437.1 - 6.3e-05 23.2 1.5 0.055 13.6 0.1 3.0 2 1 1 3 3 3 2 Aberrant zinc-finger zf-met PF12874.7 EEQ32437.1 - 0.00077 19.8 7.0 0.28 11.6 0.2 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ32437.1 - 0.2 11.7 10.9 0.22 11.6 0.5 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-LYAR PF08790.11 EEQ32437.1 - 0.31 11.0 10.1 8.4 6.4 0.4 4.6 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 EEQ32437.1 - 0.41 10.9 2.6 1.2 9.4 0.6 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Mito_carr PF00153.27 EEQ32438.1 - 1.4e-61 204.5 1.3 7.3e-20 70.7 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 EEQ32439.1 - 9.6e-35 118.2 0.0 2e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ32439.1 - 0.00022 21.3 0.0 0.0054 16.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 EEQ32439.1 - 0.0012 18.4 0.1 0.045 13.4 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas2CT1978 PF09707.10 EEQ32439.1 - 0.012 15.7 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Limkain-b1 PF11608.8 EEQ32439.1 - 0.012 15.6 0.2 0.99 9.5 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 CMV_1a_C PF12503.8 EEQ32439.1 - 0.021 14.8 0.1 4.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein C terminal PHM7_cyt PF14703.6 EEQ32439.1 - 0.086 13.1 0.8 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 EEQ32439.1 - 0.092 12.4 0.1 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_occluded PF16842.5 EEQ32439.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF2015 PF09435.10 EEQ32440.1 - 2.7e-43 146.4 0.0 3.1e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 EEQ32441.1 - 6e-33 114.0 0.1 9.5e-33 113.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.18 EEQ32442.1 - 1.3e-41 142.3 0.0 1.8e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EEQ32442.1 - 5.6e-41 139.9 0.0 1.1e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain TRAPP PF04051.16 EEQ32443.1 - 5.2e-24 84.6 2.1 7.5e-13 48.4 1.1 2.9 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component PorB PF11565.8 EEQ32443.1 - 0.082 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha helical Porin B Glyco_transf_90 PF05686.12 EEQ32444.1 - 6.6e-20 71.4 6.2 1.4e-14 53.9 6.0 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 PINIT PF14324.6 EEQ32445.1 - 3.4e-41 141.0 0.5 7.5e-41 139.9 0.5 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EEQ32445.1 - 3.6e-22 77.8 6.6 7.6e-22 76.8 6.5 1.6 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger SAP PF02037.27 EEQ32445.1 - 8e-08 31.9 0.2 2.1e-07 30.5 0.2 1.7 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 EEQ32445.1 - 8.8e-06 25.4 2.6 2e-05 24.3 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 EEQ32445.1 - 0.16 12.0 1.6 0.37 10.9 1.6 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C3HC4_2 PF13923.6 EEQ32445.1 - 4.6 7.2 6.4 9.5 6.2 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2423 PF10338.9 EEQ32446.1 - 2.2e-19 69.4 1.5 2.2e-19 69.4 1.5 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.22 EEQ32447.1 - 1.2e-11 44.8 1.2 1.9e-05 24.4 0.1 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase YqzE PF14038.6 EEQ32448.1 - 0.014 15.4 0.6 0.035 14.1 0.6 1.7 1 0 0 1 1 1 0 YqzE-like protein DUF4604 PF15377.6 EEQ32448.1 - 0.19 12.1 11.1 0.25 11.7 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RRM_2 PF04059.12 EEQ32450.1 - 1.1e-34 118.5 0.6 2e-34 117.7 0.6 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EEQ32450.1 - 7.3e-10 38.5 0.2 0.00059 19.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MSA-2c PF12238.8 EEQ32450.1 - 1.6 8.6 4.5 4.5 7.2 4.5 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c Ins_P5_2-kin PF06090.12 EEQ32451.1 - 3.1e-45 155.1 0.0 4.4e-44 151.3 0.0 1.9 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4444 PF14563.6 EEQ32451.1 - 0.008 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4444) Sec15 PF04091.12 EEQ32452.1 - 3.4e-109 365.1 0.1 1.3e-108 363.1 0.1 2.1 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG2 PF06148.11 EEQ32452.1 - 0.0013 18.8 4.8 0.0013 18.8 4.8 2.4 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 EEQ32452.1 - 0.0018 18.2 3.2 0.0018 18.2 3.2 2.4 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain PMEI PF04043.15 EEQ32452.1 - 0.04 14.3 0.4 0.091 13.1 0.4 1.6 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Sec5 PF15469.6 EEQ32452.1 - 0.046 13.5 4.2 0.44 10.3 2.3 2.9 2 0 0 2 2 2 0 Exocyst complex component Sec5 COG5 PF10392.9 EEQ32452.1 - 0.39 10.9 7.0 0.37 11.0 4.7 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 CBFD_NFYB_HMF PF00808.23 EEQ32453.1 - 1e-18 67.4 0.5 1.7e-18 66.6 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ32453.1 - 1.5e-15 57.7 0.1 1.5e-15 57.7 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EEQ32453.1 - 0.071 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.11 EEQ32454.1 - 4.8e-17 62.1 0.1 1e-16 61.1 0.1 1.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing tRNA-synt_1b PF00579.25 EEQ32455.1 - 1.8e-66 224.5 0.0 3.4e-66 223.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.22 EEQ32455.1 - 1.1e-27 96.2 0.0 3.1e-27 94.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e SWIRM PF04433.17 EEQ32457.1 - 4.9e-12 46.0 0.0 1.6e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 SWIRM domain CDC50 PF03381.15 EEQ32458.1 - 3.4e-97 325.3 0.0 5.5e-97 324.6 0.0 1.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF5083 PF16890.5 EEQ32458.1 - 0.88 9.3 3.0 1.2 8.9 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5083) SPT16 PF08644.11 EEQ32459.1 - 1e-56 191.3 0.1 2.7e-56 189.9 0.1 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EEQ32459.1 - 2.8e-55 186.5 0.1 9.5e-55 184.8 0.1 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EEQ32459.1 - 1e-26 93.9 0.0 1.7e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EEQ32459.1 - 7.3e-14 51.9 0.2 1.8e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Mito_carr PF00153.27 EEQ32460.1 - 2.1e-17 62.8 0.2 3e-11 43.1 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein GST_N_3 PF13417.6 EEQ32462.1 - 3.3e-08 33.8 0.1 9.7e-08 32.3 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EEQ32462.1 - 5.1e-08 33.1 0.0 9.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EEQ32462.1 - 1.1e-05 25.6 0.0 1.8e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ32462.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EEQ32462.1 - 0.0041 17.3 0.0 0.007 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EEQ32462.1 - 0.059 13.9 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain VitK2_biosynth PF02621.14 EEQ32462.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Menaquinone biosynthesis Sugar_tr PF00083.24 EEQ32463.1 - 8.1e-105 351.3 16.1 9.6e-105 351.0 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ32463.1 - 4.4e-31 108.1 23.5 2.6e-30 105.6 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ32463.1 - 9.6e-10 37.6 19.4 1.9e-06 26.7 4.3 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 EEQ32463.1 - 0.0045 15.9 5.2 0.79 8.5 0.0 2.4 2 0 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 EEQ32463.1 - 0.052 11.9 3.1 1 7.7 0.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector PMT PF02366.18 EEQ32464.1 - 4.9e-90 301.4 14.2 4.9e-90 301.4 14.2 2.6 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EEQ32464.1 - 4.7e-65 218.9 16.7 4.7e-65 218.9 16.7 2.1 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EEQ32464.1 - 2.9e-34 118.6 0.2 4.5e-34 117.9 0.2 1.2 1 0 0 1 1 1 1 MIR domain HKR_ArcB_TM PF18415.1 EEQ32464.1 - 7.4 7.5 7.8 0.98 10.3 0.5 3.0 2 1 1 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain Ras PF00071.22 EEQ32467.1 - 1.6e-47 161.1 0.1 1.8e-36 125.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EEQ32467.1 - 1.7e-28 99.3 0.0 1.3e-17 64.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EEQ32467.1 - 2e-08 34.0 0.1 3.9e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EEQ32467.1 - 2e-08 33.9 0.1 2.5e-07 30.3 0.1 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ32467.1 - 6e-05 22.5 0.1 0.00031 20.2 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ32467.1 - 0.00023 21.2 0.0 0.0026 17.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ32467.1 - 0.001 19.0 0.6 0.38 10.7 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EEQ32467.1 - 0.042 14.1 0.2 0.54 10.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain FAM176 PF14851.6 EEQ32467.1 - 0.097 12.3 4.2 0.15 11.7 4.2 1.2 1 0 0 1 1 1 0 FAM176 family Rrp15p PF07890.12 EEQ32467.1 - 0.12 12.7 1.1 0.17 12.2 1.1 1.2 1 0 0 1 1 1 0 Rrp15p DUF2868 PF11067.8 EEQ32467.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Pkinase PF00069.25 EEQ32468.1 - 1e-24 87.4 0.0 7.7e-24 84.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32468.1 - 1.4e-12 47.5 0.0 6e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ32468.1 - 0.00071 18.5 0.0 0.00094 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEQ32468.1 - 0.007 16.3 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EEQ32468.1 - 0.029 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_transpo PF04515.12 EEQ32470.1 - 1.8e-29 103.0 19.1 1.8e-29 103.0 19.1 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF3100 PF11299.8 EEQ32470.1 - 0.075 12.4 9.1 0.092 12.1 1.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3100) Aldo_ket_red PF00248.21 EEQ32472.1 - 1.2e-38 133.0 0.0 4.2e-37 127.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Pallilysin PF18663.1 EEQ32472.1 - 0.066 13.2 0.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Pallilysin beta barrel domain UPF0061 PF02696.14 EEQ32473.1 - 3.6e-108 362.3 0.0 4.8e-107 358.6 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family UIM PF02809.20 EEQ32474.1 - 0.3 11.1 14.2 3.7 7.7 0.3 4.2 3 0 0 3 3 3 0 Ubiquitin interaction motif MSC PF09402.10 EEQ32474.1 - 8.9 5.7 8.8 0.9 8.9 4.6 1.4 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain zf-CCHC PF00098.23 EEQ32475.1 - 1.4e-44 148.2 58.5 1.2e-07 31.5 2.6 7.2 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EEQ32475.1 - 1.7e-10 40.5 40.3 0.11 12.3 0.8 7.0 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 EEQ32475.1 - 0.0001 22.2 44.9 0.052 13.5 0.3 6.7 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 EEQ32475.1 - 0.00073 19.2 41.1 0.72 9.6 0.7 7.0 6 1 1 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EEQ32475.1 - 0.054 13.3 43.1 2.3 8.1 0.7 6.9 4 2 2 6 6 6 0 Zinc knuckle F-box PF00646.33 EEQ32476.1 - 0.00057 19.7 0.5 0.0013 18.5 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EEQ32476.1 - 0.0027 17.6 0.2 0.0064 16.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like SAE2 PF08573.10 EEQ32477.1 - 1.3e-26 93.8 5.4 9.8e-26 91.1 0.0 3.3 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus HlyD_D23 PF16576.5 EEQ32477.1 - 0.02 14.1 2.4 0.052 12.8 2.4 1.6 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Cnn_1N PF07989.11 EEQ32477.1 - 0.033 14.4 6.6 0.41 10.9 0.3 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 EEQ32477.1 - 0.31 10.1 6.4 0.84 8.7 6.4 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EEQ32477.1 - 2.2 7.5 4.7 4.2 6.5 4.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein Tropomyosin_1 PF12718.7 EEQ32477.1 - 8.6 6.5 16.6 0.85 9.8 8.3 2.9 3 0 0 3 3 3 0 Tropomyosin like APG6_N PF17675.1 EEQ32477.1 - 9.7 6.7 16.6 1.3 9.6 11.7 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Pex16 PF08610.10 EEQ32478.1 - 3.5e-142 473.3 0.4 4e-142 473.2 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.18 EEQ32479.1 - 7.4e-39 133.6 0.0 3.7e-34 118.3 0.0 2.2 1 1 1 2 2 2 2 Ribonuclease HII Mif2_N PF15624.6 EEQ32480.1 - 1.1e-35 123.3 5.9 1.1e-35 123.3 5.9 4.5 2 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 EEQ32480.1 - 1.8e-33 114.6 1.6 1.8e-33 114.6 1.6 1.9 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.11 EEQ32480.1 - 3.6e-05 23.4 0.0 8.2e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain CAP_GLY PF01302.25 EEQ32481.1 - 4.5e-27 93.8 0.0 7.8e-27 93.1 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EEQ32481.1 - 1.3e-16 60.8 0.0 2.6e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EEQ32481.1 - 1.6e-05 24.6 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.12 EEQ32482.1 - 5.9e-12 46.1 0.0 9.4e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ32482.1 - 3.4e-09 37.3 0.0 6.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ32482.1 - 1.1e-07 31.8 0.0 3.5e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ32482.1 - 1.1e-05 26.1 0.0 2.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ32482.1 - 4.7e-05 23.2 0.0 6.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EEQ32482.1 - 0.097 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Myb_DNA-binding PF00249.31 EEQ32483.1 - 5.2e-13 49.0 1.9 4.7e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ32483.1 - 6.2e-07 29.6 4.3 0.00073 19.7 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain UCH PF00443.29 EEQ32486.1 - 6e-30 104.6 0.4 7.6e-30 104.3 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ32486.1 - 2.9e-20 73.1 4.3 1e-18 68.0 4.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EEQ32486.1 - 0.00011 21.8 5.9 0.076 12.5 0.6 3.1 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase GFA PF04828.14 EEQ32486.1 - 0.025 14.9 0.8 0.06 13.7 0.8 1.7 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme SWIM PF04434.17 EEQ32487.1 - 0.069 12.8 8.3 0.091 12.5 0.2 2.6 2 0 0 2 2 2 0 SWIM zinc finger MitMem_reg PF13012.6 EEQ32488.1 - 2.4e-36 124.6 0.1 4.4e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EEQ32488.1 - 8.6e-31 106.4 0.0 2e-30 105.2 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EEQ32488.1 - 0.029 14.1 3.0 0.045 13.4 3.0 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain ADK PF00406.22 EEQ32489.1 - 1.1e-54 184.7 0.1 1.4e-54 184.3 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EEQ32489.1 - 2.5e-19 70.1 1.2 4.3e-19 69.3 0.4 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 EEQ32489.1 - 3e-17 62.3 0.0 6.3e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EEQ32489.1 - 0.00074 20.1 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EEQ32489.1 - 0.0019 17.9 0.1 0.0037 17.0 0.1 1.4 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 EEQ32489.1 - 0.0096 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEQ32489.1 - 0.055 13.2 0.1 0.1 12.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EEQ32489.1 - 0.074 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EEQ32489.1 - 0.1 11.9 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin CFIA_Pcf11 PF11526.8 EEQ32491.1 - 4.7e-12 46.2 1.0 2.7e-11 43.8 1.0 2.3 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 EEQ32491.1 - 2e-06 28.5 0.1 7.1e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 EEQ32491.1 - 0.0032 17.3 0.0 0.0091 15.9 0.0 1.7 1 0 0 1 1 1 1 VHS domain zf-C2H2_4 PF13894.6 EEQ32491.1 - 5.5 8.1 4.6 39 5.5 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 EEQ32491.1 - 7.4 6.3 9.3 18 5.0 2.5 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HOOK PF05622.12 EEQ32492.1 - 2.7e-24 85.4 33.1 2.7e-24 85.4 33.1 3.0 1 1 2 3 3 3 2 HOOK protein KASH_CCD PF14662.6 EEQ32492.1 - 2.4 7.9 87.3 0.12 12.2 17.2 6.0 2 2 4 6 6 6 0 Coiled-coil region of CCDC155 or KASH Coprogen_oxidas PF01218.18 EEQ32493.1 - 3.8e-66 222.8 0.0 1.7e-40 138.6 0.0 2.1 1 1 1 2 2 2 2 Coproporphyrinogen III oxidase NYAP_N PF15439.6 EEQ32494.1 - 0.05 12.8 0.4 0.074 12.2 0.4 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter FlgN PF05130.12 EEQ32494.1 - 0.063 13.8 0.4 0.1 13.1 0.4 1.3 1 0 0 1 1 1 0 FlgN protein Cas_DxTHG PF09455.10 EEQ32494.1 - 0.14 11.7 0.6 0.38 10.3 0.2 1.7 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family HEPN_RiboL-PSP PF18735.1 EEQ32494.1 - 0.15 12.0 1.0 0.31 10.9 0.0 1.8 2 1 0 2 2 2 0 RiboL-PSP-HEPN Mito_carr PF00153.27 EEQ32495.1 - 1e-28 99.1 1.9 2.1e-15 56.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Apc15p PF05841.11 EEQ32497.1 - 6.6e-14 52.8 0.2 1.8e-13 51.4 0.0 1.8 2 0 0 2 2 2 1 Apc15p protein Use1 PF09753.9 EEQ32498.1 - 0.0077 16.0 0.0 0.009 15.8 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF2207 PF09972.9 EEQ32498.1 - 0.076 11.8 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CHZ PF09649.10 EEQ32499.1 - 2.3e-13 49.4 0.1 2.3e-13 49.4 0.1 2.8 3 0 0 3 3 3 1 Histone chaperone domain CHZ Shugoshin_C PF07557.11 EEQ32499.1 - 0.19 11.6 0.1 0.28 11.0 0.1 1.2 1 0 0 1 1 1 0 Shugoshin C terminus CDC27 PF09507.10 EEQ32499.1 - 1.8 7.9 9.5 2.1 7.7 9.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HSP70 PF00012.20 EEQ32500.1 - 6.2e-261 866.8 7.9 7e-261 866.6 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ32500.1 - 1.8e-16 59.9 0.1 1.5e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EEQ32500.1 - 0.0038 17.0 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EEQ32500.1 - 0.013 15.9 4.2 5.4 7.5 0.0 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 EEQ32500.1 - 0.014 14.6 0.1 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EEQ32500.1 - 0.031 13.8 0.1 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Fungal_trans PF04082.18 EEQ32501.1 - 1.2e-25 90.0 0.0 1.2e-25 90.0 0.0 1.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ32501.1 - 0.086 13.0 15.1 0.16 12.1 15.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 EEQ32502.1 - 1e-30 106.9 0.3 3.4e-30 105.2 0.1 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EEQ32502.1 - 5.9e-19 68.4 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 EEQ32503.1 - 2.7e-89 300.0 32.0 3.1e-89 299.8 32.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GATase_2 PF00310.21 EEQ32505.1 - 5.4e-179 595.3 0.0 8.5e-179 594.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EEQ32505.1 - 1.1e-154 515.0 0.0 1.6e-154 514.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EEQ32505.1 - 2.5e-113 378.2 0.0 8e-112 373.3 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EEQ32505.1 - 1.3e-66 223.8 2.3 5.7e-65 218.5 2.3 2.3 1 1 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EEQ32505.1 - 4.2e-26 91.9 0.4 3.6e-25 88.8 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EEQ32505.1 - 4.3e-21 74.8 0.0 9.2e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EEQ32505.1 - 1.9e-08 34.4 0.0 7.3e-08 32.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ32505.1 - 4e-08 33.7 0.1 2.9e-05 24.5 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ32505.1 - 1.6e-07 31.3 1.3 0.0038 16.9 0.4 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EEQ32505.1 - 1.5e-06 27.7 0.1 0.029 13.6 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EEQ32505.1 - 3.3e-06 26.7 0.1 6.3e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EEQ32505.1 - 5.4e-05 22.7 0.4 5.4e-05 22.7 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EEQ32505.1 - 8.6e-05 21.4 0.2 8.6e-05 21.4 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EEQ32505.1 - 0.00014 21.0 1.9 0.00069 18.8 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 EEQ32505.1 - 0.00078 18.8 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EEQ32505.1 - 0.0052 16.1 0.1 0.34 10.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EEQ32505.1 - 0.031 14.7 1.4 3.1 8.3 0.1 3.0 3 0 0 3 3 2 0 Putative NAD(P)-binding Thi4 PF01946.17 EEQ32505.1 - 0.038 13.2 0.1 0.038 13.2 0.1 2.3 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 EEQ32505.1 - 0.042 12.9 1.9 0.1 11.6 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.19 EEQ32505.1 - 0.044 12.2 0.1 1.5 7.1 0.0 2.5 2 1 0 3 3 3 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 EEQ32505.1 - 0.098 11.7 0.1 0.27 10.2 0.1 1.8 1 0 0 1 1 1 0 Lycopene cyclase protein FMN_dh PF01070.18 EEQ32505.1 - 0.098 11.7 0.3 0.5 9.3 0.5 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_Gly3P_dh_N PF01210.23 EEQ32505.1 - 0.12 12.4 0.2 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 EEQ32505.1 - 0.14 12.2 0.0 0.69 9.9 0.0 2.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF3128 PF11326.8 EEQ32506.1 - 5.2e-27 94.0 3.8 1.1e-26 92.9 3.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF1631 PF07793.11 EEQ32506.1 - 3.1 6.1 9.0 4.2 5.7 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) RNA12 PF10443.9 EEQ32507.1 - 2.4e-149 497.9 0.4 7.6e-148 492.9 0.4 2.3 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 EEQ32507.1 - 0.00014 21.9 0.1 0.0015 18.4 0.1 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 EEQ32507.1 - 0.0035 17.1 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 EEQ32507.1 - 0.0037 17.3 0.6 0.0075 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) AAA_16 PF13191.6 EEQ32507.1 - 0.052 13.9 0.4 4 7.8 0.0 3.4 3 1 1 4 4 4 0 AAA ATPase domain PDR_CDR PF06422.12 EEQ32508.1 - 0.086 12.7 0.8 0.21 11.5 0.8 1.6 1 0 0 1 1 1 0 CDR ABC transporter p450 PF00067.22 EEQ32509.1 - 7.2e-07 28.3 0.0 0.0035 16.1 0.0 2.5 2 0 0 2 2 2 2 Cytochrome P450 Doppel PF11466.8 EEQ32509.1 - 0.0098 15.5 0.4 0.028 14.0 0.4 1.8 1 0 0 1 1 1 1 Prion-like protein Doppel Mcl1_mid PF12341.8 EEQ32510.1 - 2.7e-105 352.0 0.0 4.1e-104 348.1 0.0 2.6 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EEQ32510.1 - 1.2e-19 70.2 4.0 1.2e-08 35.4 0.1 7.6 9 0 0 9 9 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ32510.1 - 6.5e-17 61.6 0.0 0.00014 22.1 0.0 7.0 2 1 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EEQ32510.1 - 1e-08 34.7 0.0 1.2e-07 31.2 0.0 2.2 1 1 1 2 2 2 1 Coatomer WD associated region Frtz PF11768.8 EEQ32510.1 - 9.1e-05 21.0 0.0 0.13 10.5 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 EEQ32510.1 - 0.00047 20.1 0.1 0.0025 17.7 0.0 2.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.8 EEQ32510.1 - 0.021 14.9 1.2 0.062 13.4 1.2 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.12 EEQ32510.1 - 0.021 12.9 0.1 0.043 11.8 0.1 1.5 1 0 0 1 1 1 0 IKI3 family MMS1_N PF10433.9 EEQ32510.1 - 0.063 11.9 0.0 0.16 10.5 0.0 1.7 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ge1_WD40 PF16529.5 EEQ32510.1 - 0.13 11.2 0.1 2.7 6.9 0.0 2.6 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF465 PF04325.13 EEQ32510.1 - 1.3 9.1 3.9 48 4.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF465) MMU163 PF17119.5 EEQ32511.1 - 3.2e-111 370.4 0.0 4.7e-111 369.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis MFS_1 PF07690.16 EEQ32512.1 - 7e-37 127.2 14.9 7e-37 127.2 14.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ32512.1 - 3.2e-09 36.2 2.5 3.2e-09 36.2 2.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 EEQ32512.1 - 0.00071 18.6 1.0 0.0012 17.8 1.0 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 EEQ32512.1 - 0.00087 18.2 0.0 0.021 13.7 0.0 2.4 1 1 0 1 1 1 1 MFS_1 like family LacY_symp PF01306.19 EEQ32512.1 - 0.018 13.9 0.4 0.034 12.9 0.4 1.4 1 0 0 1 1 1 0 LacY proton/sugar symporter MFS_2 PF13347.6 EEQ32512.1 - 0.76 8.3 15.7 0.081 11.5 9.3 2.1 2 0 0 2 2 2 0 MFS/sugar transport protein DUF1129 PF06570.11 EEQ32512.1 - 1.6 8.1 3.2 7.9 5.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) APH PF01636.23 EEQ32513.1 - 1.8e-09 37.9 0.0 1.2e-08 35.1 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EEQ32513.1 - 0.00071 19.0 0.6 0.21 10.9 0.1 2.4 2 0 0 2 2 2 2 Ecdysteroid kinase Herpes_UL7 PF01677.16 EEQ32514.1 - 0.035 13.8 0.4 0.08 12.6 0.5 1.4 2 0 0 2 2 2 0 Herpesvirus UL7 like DUF2347 PF09804.9 EEQ32514.1 - 0.14 11.7 3.8 0.23 11.0 3.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) GRP PF07172.11 EEQ32514.1 - 0.64 10.7 25.0 2.8 8.7 25.0 2.2 1 0 0 1 1 1 0 Glycine rich protein family Muted PF14942.6 EEQ32514.1 - 0.86 9.9 12.5 2.1 8.7 12.5 1.7 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF4298 PF14131.6 EEQ32514.1 - 2.3 8.2 9.7 0.72 9.9 5.5 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) FlxA PF14282.6 EEQ32514.1 - 4.3 7.4 21.6 97 3.0 17.6 3.5 2 1 0 2 2 2 0 FlxA-like protein CBFD_NFYB_HMF PF00808.23 EEQ32515.1 - 9.5e-05 22.6 0.1 0.00016 21.9 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 EEQ32515.1 - 0.00021 21.4 0.1 0.00029 21.0 0.1 1.3 1 0 0 1 1 1 1 CENP-W protein VTC PF09359.10 EEQ32516.1 - 6.1e-85 284.9 0.0 1.1e-84 284.1 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 EEQ32516.1 - 2.6e-11 44.1 15.8 3.8e-07 30.4 0.0 4.4 2 2 2 4 4 4 3 SPX domain DUF202 PF02656.15 EEQ32516.1 - 0.0024 18.3 2.3 0.0024 18.3 2.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) 6PF2K PF01591.18 EEQ32517.1 - 3.4e-67 226.0 0.0 3.4e-45 154.1 0.0 2.1 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EEQ32517.1 - 2.5e-22 79.5 0.0 1.6e-15 57.3 0.0 2.8 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EEQ32517.1 - 9.9e-05 22.5 0.0 0.096 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF202 PF02656.15 EEQ32518.1 - 2.9e-05 24.4 1.2 6.7e-05 23.3 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) FMN_dh PF01070.18 EEQ32519.1 - 7.9e-104 347.4 0.1 1e-103 347.1 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EEQ32519.1 - 4.3e-19 68.4 0.0 1e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EEQ32519.1 - 1.1e-06 28.1 0.1 2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EEQ32519.1 - 1.2e-06 27.8 0.2 0.00034 19.7 0.0 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EEQ32519.1 - 0.012 15.1 0.8 0.078 12.4 0.3 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.21 EEQ32519.1 - 0.04 13.4 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EEQ32519.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Na_H_Exchanger PF00999.21 EEQ32521.1 - 2.8e-41 141.6 15.6 3.9e-41 141.1 15.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tetraspanin PF00335.20 EEQ32521.1 - 6.2 6.5 7.8 2 8.1 1.6 2.3 2 0 0 2 2 2 0 Tetraspanin family GFO_IDH_MocA PF01408.22 EEQ32522.1 - 1.3e-19 71.2 0.0 2.3e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_23 PF13489.6 EEQ32523.1 - 1e-11 45.0 0.0 1.7e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ32523.1 - 0.00016 21.5 0.9 0.082 12.7 0.0 2.7 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ32523.1 - 0.088 13.5 0.1 9.4 7.0 0.1 2.4 1 1 1 2 2 2 0 Methyltransferase domain ERG4_ERG24 PF01222.17 EEQ32524.1 - 1.8e-143 478.4 22.4 2.1e-143 478.2 22.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4 PF00097.25 EEQ32525.1 - 4.9e-06 26.3 9.7 9.1e-06 25.5 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ32525.1 - 3.7e-05 23.6 4.5 3.7e-05 23.6 4.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EEQ32525.1 - 0.00021 21.6 10.9 0.0036 17.6 5.1 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 EEQ32525.1 - 0.00062 19.7 6.2 0.0014 18.5 6.1 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EEQ32525.1 - 0.0011 18.8 8.0 0.0024 17.7 8.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ32525.1 - 0.0024 17.7 5.0 0.0024 17.7 5.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEQ32525.1 - 0.0027 17.8 9.0 0.016 15.3 9.2 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 EEQ32525.1 - 2.7 8.0 12.0 1.6 8.6 0.0 3.6 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.11 EEQ32525.1 - 5.2 7.0 6.6 1.3 8.9 2.0 2.3 2 0 0 2 2 2 0 GAGA factor UCH PF00443.29 EEQ32526.1 - 1.4e-42 146.0 0.0 3e-42 144.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ32526.1 - 7.6e-14 52.0 0.0 1.2e-09 38.2 0.0 2.2 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DLH PF01738.18 EEQ32528.1 - 9.5e-05 22.0 0.0 0.00011 21.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family CFIA_Pcf11 PF11526.8 EEQ32529.1 - 0.47 11.0 7.8 0.072 13.6 1.8 2.3 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Chs7 PF12271.8 EEQ32530.1 - 1.1e-99 333.5 6.4 1.3e-99 333.2 6.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2569 PF10754.9 EEQ32530.1 - 0.0015 19.0 15.2 0.0036 17.8 8.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2569) DUF1129 PF06570.11 EEQ32530.1 - 1.9 7.9 7.0 0.65 9.4 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) MpPF26 PF07666.11 EEQ32530.1 - 9.3 6.4 16.7 0.048 13.8 3.8 3.1 2 2 1 3 3 3 0 M penetrans paralogue family 26 Glyoxalase PF00903.25 EEQ32531.1 - 0.00028 21.1 0.1 0.00079 19.6 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BC10 PF06726.12 EEQ32532.1 - 4.7e-17 62.0 9.9 9e-17 61.1 9.9 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Ge1_WD40 PF16529.5 EEQ32533.1 - 0.00014 21.0 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Importin_rep_6 PF18829.1 EEQ32533.1 - 0.13 12.4 0.2 0.39 10.9 0.2 1.7 1 0 0 1 1 1 0 Importin repeat 6 IZUMO PF15005.6 EEQ32533.1 - 2.3 8.7 4.6 1.3 9.5 0.5 2.5 1 1 2 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated dCMP_cyt_deam_1 PF00383.23 EEQ32534.1 - 7.2e-06 25.8 0.0 1.8e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.11 EEQ32535.1 - 7.6e-31 107.7 0.4 2.8e-30 105.8 0.0 2.1 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EEQ32535.1 - 0.00046 19.9 0.0 0.00046 19.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Spt20 PF12090.8 EEQ32535.1 - 0.015 15.0 12.8 0.015 15.0 12.8 2.2 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 EEQ32535.1 - 2.4 6.9 6.7 3.6 6.2 6.7 1.3 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 EEQ32535.1 - 2.9 7.9 9.8 0.19 11.8 3.6 1.9 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Arm PF00514.23 EEQ32536.1 - 1.6e-14 53.4 8.1 0.041 13.9 0.0 8.6 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EEQ32536.1 - 0.11 12.8 15.3 3.5 8.1 0.1 7.0 8 0 0 8 8 8 0 HEAT repeat adh_short PF00106.25 EEQ32537.1 - 3.2e-12 46.3 0.0 1.3e-08 34.6 0.0 3.0 1 1 2 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ32537.1 - 2.4e-11 43.6 0.0 1.9e-05 24.4 0.0 2.9 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Fructosamin_kin PF03881.14 EEQ32538.1 - 9.5e-57 192.4 0.0 4.8e-56 190.1 0.0 1.8 1 1 0 1 1 1 1 Fructosamine kinase GST_N_2 PF13409.6 EEQ32539.1 - 1.9e-15 56.9 0.1 3.8e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ32539.1 - 3e-14 53.2 0.1 6.1e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EEQ32539.1 - 6.1e-05 23.3 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ32539.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EEQ32539.1 - 0.18 12.4 0.0 0.32 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-C2H2 PF00096.26 EEQ32540.1 - 8.4e-16 57.5 27.6 0.0018 18.6 0.1 8.6 7 1 1 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ32540.1 - 8.7e-12 44.8 33.2 0.14 13.1 0.1 8.7 8 0 0 8 8 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ32540.1 - 2.6e-11 43.5 36.1 0.0004 20.6 0.4 7.8 7 2 2 9 9 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ32540.1 - 8e-09 35.6 29.1 0.015 15.6 0.1 7.6 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ32540.1 - 0.0023 17.9 0.2 0.0023 17.9 0.2 6.6 7 0 0 7 7 7 1 C2H2-type zinc finger zf_UBZ PF18439.1 EEQ32540.1 - 0.003 17.1 13.5 2 8.1 1.0 5.4 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 EEQ32540.1 - 0.12 12.7 42.6 1.1 9.7 4.9 5.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 EEQ32540.1 - 0.64 9.9 19.3 0.89 9.4 0.1 5.8 4 1 2 6 6 6 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_12 PF11331.8 EEQ32540.1 - 1.1 9.2 16.4 0.16 11.8 1.6 3.7 3 0 0 3 3 3 0 Probable zinc-ribbon domain DUF4187 PF13821.6 EEQ32540.1 - 1.7 8.5 0.0 1.7 8.5 0.0 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4187) zf-C2H2_11 PF16622.5 EEQ32540.1 - 4.7 7.1 19.5 1.7 8.5 0.0 5.5 6 0 0 6 6 6 0 zinc-finger C2H2-type Cyclin_N PF00134.23 EEQ32541.1 - 3.1e-08 33.4 0.1 3.7e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain MRP-S34 PF16053.5 EEQ32541.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 DNA_pol_B_N PF18094.1 EEQ32541.1 - 0.06 13.9 0.0 0.16 12.5 0.0 1.7 1 1 1 2 2 2 0 DNA polymerase beta N-terminal domain CTP_transf_1 PF01148.20 EEQ32542.1 - 8.4e-82 274.9 21.8 1e-81 274.6 21.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 EEQ32543.1 - 4.3e-44 149.9 0.2 1.6e-43 148.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3636) Bap31_Bap29_C PF18035.1 EEQ32543.1 - 0.0045 17.0 0.4 0.019 15.0 0.4 2.1 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Takusan PF04822.13 EEQ32543.1 - 0.011 15.6 0.7 0.031 14.2 0.7 1.8 1 0 0 1 1 1 0 Takusan TMF_TATA_bd PF12325.8 EEQ32543.1 - 0.057 13.6 7.7 0.14 12.4 7.7 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1192 PF06698.11 EEQ32543.1 - 0.097 12.7 5.2 0.34 11.0 5.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4140 PF13600.6 EEQ32543.1 - 0.27 11.7 10.0 0.058 13.8 3.0 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-C4H2 PF10146.9 EEQ32543.1 - 0.37 11.1 7.9 0.9 9.8 7.9 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4164 PF13747.6 EEQ32543.1 - 0.57 10.5 11.4 0.043 14.1 1.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) LCD1 PF09798.9 EEQ32543.1 - 3.2 6.1 14.5 0.38 9.2 0.0 2.9 2 1 1 3 3 3 0 DNA damage checkpoint protein PRKG1_interact PF15898.5 EEQ32543.1 - 7.9 7.4 12.0 2.9 8.8 8.0 2.4 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain FA_desaturase PF00487.24 EEQ32544.1 - 1.1e-06 28.8 18.0 1.1e-06 28.8 18.0 2.1 1 1 1 2 2 2 2 Fatty acid desaturase GDPD PF03009.17 EEQ32545.1 - 3.4e-17 63.1 0.0 4.6e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MFS_1 PF07690.16 EEQ32546.1 - 1.2e-17 63.9 18.7 6e-16 58.3 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 EEQ32546.1 - 5.5 7.5 6.8 0.66 10.5 1.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Sterol_MT_C PF08498.10 EEQ32547.1 - 4e-26 91.1 0.3 7.2e-26 90.3 0.3 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 EEQ32547.1 - 2.2e-18 66.5 0.0 3.3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ32547.1 - 5.7e-18 65.4 0.0 1.3e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ32547.1 - 1.6e-17 64.0 0.0 3.6e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EEQ32547.1 - 1.4e-13 50.8 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EEQ32547.1 - 1.9e-11 44.1 0.0 3.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ32547.1 - 9.8e-10 38.2 0.0 1.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EEQ32547.1 - 1.2e-09 38.8 0.1 3.1e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EEQ32547.1 - 2.2e-06 27.6 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EEQ32547.1 - 0.0029 17.2 0.1 0.0047 16.5 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase B PF02216.16 EEQ32547.1 - 0.0065 16.4 0.1 0.015 15.2 0.1 1.6 1 0 0 1 1 1 1 B domain Methyltransf_2 PF00891.18 EEQ32547.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 EEQ32547.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 EEQ32547.1 - 0.022 14.7 0.1 0.047 13.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 EEQ32547.1 - 0.029 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DRE2_N PF16803.5 EEQ32547.1 - 0.055 13.7 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus RrnaAD PF00398.20 EEQ32547.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase adh_short PF00106.25 EEQ32548.1 - 6.1e-16 58.5 0.0 6.6e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.12 EEQ32548.1 - 9.8e-05 21.6 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EEQ32548.1 - 0.00085 19.3 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EEQ32548.1 - 0.0014 18.6 0.0 0.0039 17.1 0.0 1.8 3 0 0 3 3 3 1 KR domain Epimerase PF01370.21 EEQ32548.1 - 0.0071 15.8 0.0 0.065 12.7 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EEQ32548.1 - 0.058 12.5 0.0 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 EEQ32550.1 - 2.8e-31 108.7 28.5 2.8e-31 108.7 28.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EEQ32550.1 - 0.99 7.6 8.6 0.49 8.6 4.9 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF5090 PF17009.5 EEQ32551.1 - 0.64 9.9 4.4 0.71 9.8 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5090) Methyltransf_31 PF13847.6 EEQ32552.1 - 4e-07 29.9 0.0 7.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 EEQ32552.1 - 2.5e-06 27.1 0.0 5.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 RNA methyltransferase Methyltransf_25 PF13649.6 EEQ32552.1 - 6e-06 26.9 0.0 1.4e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEQ32552.1 - 9e-06 25.3 0.0 0.00088 18.9 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase small domain PrmC_N PF17827.1 EEQ32552.1 - 3e-05 24.5 0.5 0.00012 22.6 0.4 2.1 1 1 0 1 1 1 1 PrmC N-terminal domain PrmA PF06325.13 EEQ32552.1 - 0.00029 20.3 0.0 0.00043 19.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.16 EEQ32552.1 - 0.0011 18.3 0.0 0.0023 17.2 0.0 1.4 1 1 0 1 1 1 1 N-6 DNA Methylase Ubie_methyltran PF01209.18 EEQ32552.1 - 0.0062 15.9 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AviRa PF11599.8 EEQ32552.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 EEQ32552.1 - 0.034 14.9 0.0 0.062 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ32552.1 - 0.034 14.8 0.0 0.07 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.23 EEQ32553.1 - 2.3e-60 204.7 0.1 3.5e-60 204.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEQ32553.1 - 2.2e-10 41.0 2.0 2.7e-06 27.8 2.1 3.5 2 2 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EEQ32553.1 - 3.6e-06 27.5 0.9 0.015 15.9 0.2 3.8 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EEQ32553.1 - 0.00015 22.2 0.0 0.071 13.7 0.0 3.4 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease Lipocalin_4 PF13648.6 EEQ32553.1 - 0.3 12.1 1.3 4.5 8.3 0.3 2.4 2 0 0 2 2 2 0 Lipocalin-like domain Phage_holin_3_6 PF07332.11 EEQ32554.1 - 9.6 6.3 17.7 3.5 7.7 1.0 3.2 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III zf-C2H2_jaz PF12171.8 EEQ32556.1 - 0.053 13.8 1.0 2.5 8.5 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ32556.1 - 0.52 10.8 8.8 7.5 7.1 1.2 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Thiamine_BP PF01910.17 EEQ32557.1 - 2.6e-28 97.8 0.5 3.2e-28 97.5 0.5 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Retro_M PF02813.14 EEQ32557.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Retroviral M domain TPR_8 PF13181.6 EEQ32558.1 - 0.0018 18.3 7.6 0.25 11.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ32558.1 - 0.0023 18.2 2.1 4.4 7.7 0.6 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ32558.1 - 0.0032 18.2 2.2 5.2 8.1 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 EEQ32558.1 - 0.0046 17.0 0.1 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 EEQ32558.1 - 0.013 16.1 2.0 12 6.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ32558.1 - 0.058 13.5 8.7 2.9 8.2 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ32558.1 - 0.3 10.8 0.0 0.3 10.8 0.0 3.2 4 0 0 4 4 4 0 TPR repeat TPR_10 PF13374.6 EEQ32558.1 - 3.7 7.6 6.4 12 5.9 0.9 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PH_10 PF15411.6 EEQ32560.1 - 9.9e-27 93.6 0.4 1.8e-26 92.8 0.4 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EEQ32560.1 - 1.5e-12 48.1 0.0 2.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EEQ32560.1 - 4.6e-08 33.1 0.1 6.1e-07 29.5 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EEQ32560.1 - 7e-06 26.7 0.0 1.7e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.6 EEQ32560.1 - 0.00074 19.4 4.3 0.0013 18.6 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EEQ32560.1 - 0.0013 19.0 5.3 0.0024 18.1 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ32560.1 - 0.051 13.4 4.5 0.098 12.5 4.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ32560.1 - 0.055 13.4 4.4 0.1 12.5 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ32560.1 - 0.064 13.1 2.0 0.12 12.2 2.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH_5 PF15405.6 EEQ32560.1 - 0.12 12.4 0.1 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Zn_ribbon_17 PF17120.5 EEQ32560.1 - 0.43 10.2 6.1 0.16 11.6 3.0 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EEQ32560.1 - 0.76 9.7 3.9 1.5 8.7 3.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 EEQ32560.1 - 0.94 9.8 3.5 1.8 9.0 3.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 EEQ32560.1 - 5.9 7.0 7.7 11 6.1 5.6 2.4 2 1 0 2 2 2 0 Zinc-finger Ribosomal_L12 PF00542.19 EEQ32561.1 - 1e-21 77.0 8.9 1.6e-20 73.2 6.2 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EEQ32561.1 - 6.2e-12 45.0 9.8 6.2e-12 45.0 9.8 3.2 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 EEQ32561.1 - 0.00059 20.4 5.0 0.00059 20.4 5.0 2.1 2 1 0 2 2 2 1 60s Acidic ribosomal protein SpoVIF PF14069.6 EEQ32561.1 - 0.084 12.7 3.2 0.2 11.5 0.9 2.5 2 1 0 2 2 2 0 Stage VI sporulation protein F Cpn60_TCP1 PF00118.24 EEQ32562.1 - 3.7e-147 490.9 6.3 4.2e-147 490.7 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 EEQ32562.1 - 0.064 12.8 0.2 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 Propionate catabolism activator EAL PF00563.20 EEQ32562.1 - 0.074 12.6 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 EAL domain RXT2_N PF08595.11 EEQ32562.1 - 0.13 12.3 1.6 0.37 10.8 1.6 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Radial_spoke PF04712.12 EEQ32562.1 - 0.18 10.7 2.8 0.28 10.1 2.8 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Na_trans_assoc PF06512.13 EEQ32562.1 - 0.22 11.8 2.8 0.39 11.0 2.8 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4611 PF15387.6 EEQ32562.1 - 0.52 10.6 7.1 1.2 9.4 7.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 EEQ32562.1 - 0.95 9.1 5.0 1.8 8.2 5.0 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EEQ32562.1 - 1.1 8.6 5.6 1.6 8.0 5.6 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EEQ32562.1 - 1.7 9.1 8.9 3.8 8.0 8.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Dicty_REP PF05086.12 EEQ32562.1 - 3.5 5.5 4.2 4.8 5.0 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_phi PF04931.13 EEQ32562.1 - 7.6 4.5 9.5 11 4.0 9.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi E1_dh PF00676.20 EEQ32563.1 - 3.3e-112 374.3 0.3 4.1e-112 374.0 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EEQ32563.1 - 6.8e-05 22.2 0.1 0.00014 21.1 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase S4 PF01479.25 EEQ32565.1 - 1.9e-15 56.3 0.0 3.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EEQ32565.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 S4 domain SSP160 PF06933.11 EEQ32565.1 - 0.4 8.8 10.3 0.55 8.4 10.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NPV_P10 PF05531.12 EEQ32565.1 - 0.52 10.8 2.4 3.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PriC PF07445.12 EEQ32565.1 - 0.72 9.8 8.2 1.8 8.4 7.8 1.8 1 1 0 1 1 1 0 Primosomal replication protein priC DUF3439 PF11921.8 EEQ32565.1 - 0.78 9.7 7.8 0.82 9.6 5.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) XRN_M PF17846.1 EEQ32565.1 - 0.85 8.5 4.3 0.35 9.8 0.8 1.8 1 1 1 2 2 2 0 Xrn1 helical domain Abhydrolase_1 PF00561.20 EEQ32566.1 - 2.4e-24 86.4 0.1 1.2e-22 80.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ32566.1 - 5.6e-20 72.9 0.5 7.1e-20 72.6 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ32566.1 - 2.2e-09 36.9 0.0 4.8e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EEQ32566.1 - 0.00049 19.9 0.3 0.17 11.6 0.3 2.1 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 EEQ32566.1 - 0.0064 16.2 0.2 0.015 15.0 0.2 1.7 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 EEQ32566.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydro_lipase PF04083.16 EEQ32566.1 - 0.028 14.0 0.0 0.069 12.7 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_2 PF02230.16 EEQ32566.1 - 0.042 13.6 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 EEQ32566.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 EEQ32566.1 - 0.22 11.4 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase AA_permease_2 PF13520.6 EEQ32567.1 - 3.7e-63 213.8 43.8 5e-63 213.4 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ32567.1 - 4.3e-26 91.5 30.6 4.3e-26 91.5 30.6 2.1 2 0 0 2 2 2 2 Amino acid permease NAD_binding_1 PF00175.21 EEQ32568.1 - 3.3e-08 34.2 0.0 0.00021 21.9 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEQ32568.1 - 0.0002 21.6 0.0 0.00064 20.0 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EEQ32568.1 - 0.034 14.3 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Aminotran_5 PF00266.19 EEQ32569.1 - 3.5e-26 92.0 0.0 2.4e-14 53.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.20 EEQ32570.1 - 6.1e-113 378.2 0.3 5.3e-112 375.2 0.3 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEQ32570.1 - 4.2e-24 85.3 0.0 1e-23 84.1 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF5068 PF16781.5 EEQ32570.1 - 0.0029 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5068) Peptidase_M22 PF00814.25 EEQ32571.1 - 6.1e-84 281.9 0.0 1e-83 281.2 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EEQ32571.1 - 0.092 12.4 0.1 0.28 10.8 0.1 1.7 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus SET PF00856.28 EEQ32572.1 - 1.8e-16 61.0 0.0 5e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EEQ32572.1 - 2.4e-09 37.9 0.1 5.9e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding EPL1 PF10513.9 EEQ32573.1 - 8.5e-21 75.0 0.3 8.5e-21 75.0 0.3 3.1 2 1 1 3 3 3 1 Enhancer of polycomb-like DUF2535 PF10751.9 EEQ32573.1 - 0.094 13.2 0.0 0.53 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2535) EF-hand_1 PF00036.32 EEQ32574.1 - 4.1e-27 91.7 12.3 9.4e-08 31.1 0.5 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EEQ32574.1 - 1.6e-21 76.5 8.0 2.3e-13 50.4 1.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EEQ32574.1 - 1.4e-20 71.4 6.0 6.2e-05 22.6 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EEQ32574.1 - 1.3e-17 62.4 10.6 2.1e-06 27.0 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EEQ32574.1 - 2.2e-14 53.0 8.2 7.1e-05 22.6 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EEQ32574.1 - 5.1e-06 26.8 0.0 0.01 16.1 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EEQ32574.1 - 7.2e-05 22.7 8.6 0.016 15.2 0.3 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EEQ32574.1 - 0.049 14.0 0.1 0.93 9.9 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain HflK_N PF12221.8 EEQ32575.1 - 0.013 15.5 0.0 0.049 13.6 0.0 2.0 1 0 0 1 1 1 0 Bacterial membrane protein N terminal DUF3391 PF11871.8 EEQ32575.1 - 0.11 13.0 0.7 0.48 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF3966 PF13110.6 EEQ32576.1 - 0.096 12.6 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) Ribosomal_S9 PF00380.19 EEQ32577.1 - 3.3e-39 134.2 1.2 5.3e-39 133.5 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 EEQ32578.1 - 4.7e-47 158.5 0.3 8e-47 157.7 0.3 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EEQ32578.1 - 2.6e-13 50.0 0.0 5.8e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EEQ32578.1 - 1.6e-11 44.4 0.0 4.4e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ32578.1 - 1.9e-08 34.6 0.0 4.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ32578.1 - 5.5e-08 32.7 0.0 1.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ32578.1 - 2.8e-06 27.4 0.0 7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EEQ32578.1 - 0.0006 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.18 EEQ32579.1 - 8.2e-27 93.9 1.5 3.7e-26 91.8 1.5 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase RRP36 PF06102.12 EEQ32580.1 - 3e-47 160.7 27.9 3e-47 160.7 27.9 2.2 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 DUF1757 PF08560.10 EEQ32583.1 - 0.00013 22.0 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) AMPK1_CBM PF16561.5 EEQ32584.1 - 5e-30 103.6 0.1 8.4e-30 102.8 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EEQ32584.1 - 5.1e-18 65.1 1.6 1.1e-17 64.1 0.5 2.2 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Mannosyl_trans3 PF11051.8 EEQ32586.1 - 4.5e-59 200.1 0.1 1.7e-33 116.1 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative DUF4303 PF14136.6 EEQ32586.1 - 0.18 11.5 0.3 0.36 10.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) ABC1 PF03109.16 EEQ32587.1 - 5.3e-33 113.7 0.0 1.4e-32 112.3 0.0 1.8 1 0 0 1 1 1 1 ABC1 family UreF PF01730.16 EEQ32588.1 - 5.8e-13 49.6 2.0 1e-11 45.6 2.0 2.1 1 1 0 1 1 1 1 UreF BRE1 PF08647.11 EEQ32589.1 - 3.6e-25 87.9 15.9 3.6e-25 87.9 15.9 6.6 4 2 2 6 6 6 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EEQ32589.1 - 4e-10 39.4 7.9 6.9e-10 38.6 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ32589.1 - 2.3e-09 37.0 8.5 5.1e-09 35.8 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ32589.1 - 9.4e-08 31.8 10.8 1.8e-07 30.9 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ32589.1 - 1e-07 31.8 6.4 2.2e-07 30.8 6.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EEQ32589.1 - 1.1e-07 32.1 9.1 2e-07 31.2 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EEQ32589.1 - 2.2e-07 30.6 8.5 4e-07 29.8 8.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EEQ32589.1 - 2.1e-06 27.6 11.2 3.9e-06 26.7 11.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF745 PF05335.13 EEQ32589.1 - 0.00015 21.6 6.9 0.00015 21.6 6.9 5.6 3 2 3 6 6 6 1 Protein of unknown function (DUF745) zf-C3HC4_4 PF15227.6 EEQ32589.1 - 0.0017 18.5 7.0 0.0033 17.5 7.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EEQ32589.1 - 0.0019 18.4 5.5 0.0064 16.7 5.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF1272 PF06906.11 EEQ32589.1 - 0.017 15.2 5.5 0.036 14.2 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) SPATA1_C PF15743.5 EEQ32589.1 - 0.021 14.9 1.6 0.021 14.9 1.6 5.0 2 1 2 4 4 3 0 Spermatogenesis-associated C-terminus zf-RING_10 PF16685.5 EEQ32589.1 - 0.03 14.4 7.1 0.079 13.1 7.1 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 GP41 PF00517.17 EEQ32589.1 - 0.048 13.6 0.1 0.048 13.6 0.1 4.0 5 0 0 5 5 5 0 Retroviral envelope protein zf-RING_4 PF14570.6 EEQ32589.1 - 0.069 12.9 7.8 0.55 10.1 8.5 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain SSURE PF11966.8 EEQ32589.1 - 0.14 12.0 0.2 0.45 10.3 0.2 1.9 1 0 0 1 1 1 0 Fibronectin-binding repeat zf-UDP PF14569.6 EEQ32589.1 - 0.43 10.7 3.9 1.1 9.4 3.9 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-Nse PF11789.8 EEQ32589.1 - 0.46 10.3 5.7 1.1 9.1 5.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 EEQ32589.1 - 1 9.5 6.3 2.3 8.3 6.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.6 EEQ32589.1 - 1.1 9.1 4.0 2.3 8.1 4.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HALZ PF02183.18 EEQ32589.1 - 1.8 8.8 26.3 16 5.8 3.2 6.4 6 0 0 6 6 5 0 Homeobox associated leucine zipper FYVE PF01363.21 EEQ32589.1 - 1.9 8.7 13.1 1.3 9.2 6.7 2.6 1 1 1 2 2 2 0 FYVE zinc finger Myb_DNA-bind_4 PF13837.6 EEQ32589.1 - 6.7 7.2 11.0 1.1 9.7 0.1 3.8 4 0 0 4 4 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EEQ32590.1 - 2.6e-26 91.3 0.3 2.6e-26 91.3 0.3 2.5 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EEQ32590.1 - 0.0002 21.5 0.0 0.00092 19.4 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SARAF PF06682.12 EEQ32591.1 - 2.2e-85 287.3 8.3 1.3e-83 281.4 8.3 2.0 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis MMM1 PF10296.9 EEQ32592.1 - 2.6e-135 450.7 0.0 3.2e-135 450.5 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ARD PF03079.14 EEQ32593.1 - 1.4e-46 158.5 0.3 1.6e-46 158.3 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EEQ32593.1 - 6e-09 35.5 0.2 9.4e-09 34.9 0.2 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EEQ32593.1 - 1.6e-05 24.8 0.1 2.5e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 EEQ32593.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 EEQ32593.1 - 0.03 13.9 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Cupin GIDA PF01134.22 EEQ32594.1 - 1.2e-154 515.2 0.0 1.6e-154 514.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EEQ32594.1 - 3.7e-66 223.3 0.0 4.9e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 EEQ32594.1 - 3.6e-06 26.4 0.2 6.7e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EEQ32594.1 - 5.3e-06 26.0 0.3 7.4e-06 25.6 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EEQ32594.1 - 0.00039 19.6 0.9 0.00079 18.6 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EEQ32594.1 - 0.0033 16.8 0.1 0.04 13.2 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EEQ32594.1 - 0.016 14.1 0.1 0.81 8.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 EEQ32594.1 - 0.018 13.8 1.1 0.12 11.1 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 EEQ32594.1 - 0.047 13.3 0.6 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EEQ32594.1 - 0.24 10.6 0.1 0.8 8.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3605 PF12239.8 EEQ32595.1 - 2.6e-50 170.7 3.7 3.4e-50 170.3 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) APH PF01636.23 EEQ32596.1 - 7.9e-15 55.4 0.0 1.5e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EEQ32596.1 - 0.21 10.9 0.0 0.73 9.1 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase Sec1 PF00995.23 EEQ32597.1 - 1e-132 444.3 0.0 1.2e-132 444.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Spectrin_like PF18373.1 EEQ32597.1 - 0.13 12.3 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Spectrin like domain adh_short PF00106.25 EEQ32598.1 - 1.9e-33 115.6 0.0 2.6e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ32598.1 - 9e-25 87.6 0.0 1.2e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ32598.1 - 2e-09 37.6 0.0 2.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ32598.1 - 2.3e-07 30.5 0.1 5.5e-07 29.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EEQ32598.1 - 0.00025 20.3 0.0 0.00056 19.1 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EEQ32598.1 - 0.00031 20.0 0.0 0.0004 19.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EEQ32598.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ32598.1 - 0.025 14.1 0.0 0.059 12.9 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 EEQ32598.1 - 0.027 13.5 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EEQ32598.1 - 0.1 11.8 0.0 12 5.0 0.0 2.9 2 1 1 3 3 3 0 Male sterility protein NAD_binding_8 PF13450.6 EEQ32599.1 - 3.3e-14 52.9 0.1 1.2e-13 51.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ32599.1 - 3.1e-09 36.9 0.0 2.8e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ32599.1 - 5.3e-08 32.4 0.1 3.7e-05 23.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EEQ32599.1 - 1.1e-07 31.6 0.0 5.1e-07 29.3 0.0 2.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EEQ32599.1 - 6.5e-06 25.5 0.1 3.4e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EEQ32599.1 - 9.4e-06 25.0 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EEQ32599.1 - 3.7e-05 22.6 0.3 0.0006 18.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EEQ32599.1 - 0.00011 22.7 0.2 0.089 13.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EEQ32599.1 - 0.0013 17.7 0.6 0.019 13.8 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 EEQ32599.1 - 0.002 18.1 0.1 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EEQ32599.1 - 0.0022 17.4 0.0 0.0075 15.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EEQ32599.1 - 0.0098 15.2 0.0 0.045 13.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EEQ32599.1 - 0.012 14.9 0.0 0.24 10.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ32599.1 - 0.033 13.2 0.1 0.05 12.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 EEQ32599.1 - 0.058 13.0 0.0 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 EEQ32599.1 - 0.076 12.1 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A CAP_assoc_N PF14504.6 EEQ32599.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 CAP-associated N-terminal Tyr-DNA_phospho PF06087.12 EEQ32600.1 - 7.1e-52 176.7 0.0 1.5e-51 175.7 0.0 1.6 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DUF4568 PF15132.6 EEQ32600.1 - 0.11 11.8 0.0 8.1 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4568) Gti1_Pac2 PF09729.9 EEQ32601.1 - 1.3e-62 211.1 4.0 6.5e-61 205.6 0.0 2.7 2 1 0 2 2 2 1 Gti1/Pac2 family Spt20 PF12090.8 EEQ32601.1 - 5.1 6.6 34.5 1.7 8.2 24.2 2.4 2 0 0 2 2 2 0 Spt20 family CDP-OH_P_transf PF01066.21 EEQ32602.1 - 5.1e-14 52.8 0.6 5.1e-14 52.8 0.6 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase BssB_TutG PF18512.1 EEQ32602.1 - 0.071 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Benzylsuccinate synthase beta subunit MBOAT PF03062.19 EEQ32603.1 - 8e-55 186.6 3.4 1.6e-54 185.6 3.4 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_60s PF00428.19 EEQ32603.1 - 0.84 10.3 9.0 1.9 9.1 9.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein 5_nucleotid PF05761.14 EEQ32604.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family Trypan_PARP PF05887.11 EEQ32604.1 - 0.28 11.1 6.8 0.72 9.8 6.8 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CPBP PF02517.16 EEQ32605.1 - 9.3e-16 58.0 4.4 9.3e-16 58.0 4.4 2.4 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Suc_Fer-like PF06999.12 EEQ32606.1 - 4.3e-59 199.7 0.0 4.9e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like HofP PF10748.9 EEQ32606.1 - 0.0037 16.8 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 DNA utilization proteins HofP OmdA PF13376.6 EEQ32606.1 - 0.22 11.5 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated zf-C2H2_2 PF12756.7 EEQ32607.1 - 8.3e-21 74.2 4.0 7.8e-20 71.1 3.4 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EEQ32607.1 - 0.004 17.5 0.0 0.01 16.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type tRNA-synt_1 PF00133.22 EEQ32608.1 - 1.2e-54 185.7 0.0 6.4e-25 87.4 0.2 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EEQ32608.1 - 3.9e-38 130.8 0.0 6.2e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EEQ32608.1 - 3.8e-32 111.5 0.2 1.2e-23 83.6 0.0 4.1 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EEQ32608.1 - 2e-13 50.6 0.0 3.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EEQ32608.1 - 5.5e-07 29.2 0.0 3.9e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 EEQ32608.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) tRNA-synt_1c PF00749.21 EEQ32608.1 - 0.1 11.5 0.1 6.6 5.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Auto_anti-p27 PF06677.12 EEQ32608.1 - 0.9 9.8 2.7 0.42 10.8 0.1 1.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Cation_ATPase_C PF00689.21 EEQ32609.1 - 0.09 12.5 1.3 0.15 11.8 1.3 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus 2-Hacid_dh_C PF02826.19 EEQ32611.1 - 8.1e-50 168.6 0.0 1.2e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ32611.1 - 1.4e-16 60.4 0.0 2.1e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EEQ32611.1 - 0.0003 21.0 0.0 0.001 19.3 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase FH2 PF02181.23 EEQ32614.1 - 7.8e-84 281.9 5.1 7.8e-84 281.9 5.1 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EEQ32614.1 - 2.4e-67 226.2 0.0 2.4e-67 226.2 0.0 2.2 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EEQ32614.1 - 9.5e-27 93.9 0.3 7.8e-21 74.6 0.1 3.8 1 1 1 2 2 2 2 Diaphanous FH3 Domain TrmE_N PF10396.9 EEQ32616.1 - 1.8e-35 121.7 0.0 4.3e-35 120.5 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EEQ32616.1 - 9.2e-29 101.1 0.0 2.4e-28 99.7 0.0 1.6 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EEQ32616.1 - 1e-17 64.2 0.1 1.8e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EEQ32616.1 - 1.5e-05 25.1 0.1 3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 EEQ32616.1 - 5.8e-05 22.7 0.2 0.00028 20.4 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EEQ32616.1 - 0.00012 21.6 0.1 0.0039 16.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EEQ32616.1 - 0.036 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.22 EEQ32616.1 - 0.065 13.2 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain ABC_tran PF00005.27 EEQ32616.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 EEQ32616.1 - 0.14 12.4 0.0 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_pol_L_2 PF13656.6 EEQ32617.1 - 6.4e-34 115.6 0.0 8.8e-34 115.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EEQ32617.1 - 3.1e-14 52.1 0.0 4.4e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 EEQ32618.1 - 1.6e-06 28.8 0.4 2.5e-06 28.1 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EEQ32618.1 - 0.00012 22.1 0.2 0.00024 21.1 0.2 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Clathrin_H_link PF13838.6 EEQ32618.1 - 0.13 12.2 0.8 4.2 7.4 0.0 2.4 2 1 0 2 2 2 0 Clathrin-H-link DUF5301 PF17225.3 EEQ32619.1 - 0.049 14.1 0.0 0.049 14.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) Abhydrolase_1 PF00561.20 EEQ32620.1 - 5.4e-15 55.7 0.1 3.4e-14 53.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ32620.1 - 1.1e-10 41.2 0.0 5.8e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 EEQ32620.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Zn_clus PF00172.18 EEQ32621.1 - 0.00041 20.4 9.0 0.0015 18.6 9.0 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EEQ32622.1 - 1.3e-33 116.4 26.4 1.3e-33 116.4 26.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ32622.1 - 5.7e-10 38.6 4.4 5.7e-10 38.6 4.4 2.1 2 1 1 3 3 3 1 Sugar (and other) transporter Beta_elim_lyase PF01212.21 EEQ32623.1 - 1.7e-56 191.7 0.0 2e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EEQ32623.1 - 0.015 13.9 0.0 0.023 13.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Trp_DMAT PF11991.8 EEQ32624.1 - 3.4e-112 375.5 0.0 4e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase TRAPPC9-Trs120 PF08626.11 EEQ32625.1 - 0 1454.9 0.0 0 1454.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF3684 PF12449.8 EEQ32626.1 - 0 1437.0 0.0 0 1436.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EEQ32626.1 - 0.00037 20.3 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 EEQ32626.1 - 0.82 9.7 7.1 0.12 12.4 0.4 2.4 2 0 0 2 2 2 0 WLM domain DUF2756 PF10956.8 EEQ32626.1 - 1.8 9.1 7.3 4.7 7.8 7.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Activator_LAG-3 PF11498.8 EEQ32626.1 - 6.5 5.6 13.8 11 4.9 13.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pro-kuma_activ PF09286.11 EEQ32627.1 - 7.6e-40 136.5 1.5 1.3e-39 135.7 1.5 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EEQ32627.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Subtilase family RdRP PF05183.12 EEQ32630.1 - 2.7e-181 604.2 0.0 3.3e-181 603.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Med6 PF04934.14 EEQ32631.1 - 1e-38 132.1 0.0 4.4e-38 130.1 0.0 1.8 2 0 0 2 2 2 1 MED6 mediator sub complex component Lysine_decarbox PF03641.14 EEQ32632.1 - 3.6e-29 101.5 0.0 5.5e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EEQ32632.1 - 0.0023 17.6 1.3 0.0033 17.0 0.2 1.8 2 0 0 2 2 2 1 SLOG cluster4 family Proteasome PF00227.26 EEQ32633.1 - 4.6e-49 166.5 0.4 6.1e-49 166.1 0.4 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEQ32633.1 - 2.7e-12 46.1 1.1 5e-12 45.3 0.3 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.16 EEQ32633.1 - 0.17 11.8 0.3 29 4.6 0.1 3.1 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Vps55 PF04133.14 EEQ32634.1 - 1.3e-45 154.1 9.1 1.5e-45 153.9 9.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 EEQ32634.1 - 0.76 9.2 0.0 0.76 9.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Sld7_C PF18596.1 EEQ32635.1 - 3.2e-10 40.0 0.0 2.2e-09 37.3 0.0 2.4 1 1 0 1 1 1 1 Sld7 C-terminal domain UPF0220 PF05255.11 EEQ32636.1 - 9.4e-69 230.2 6.6 1.1e-68 230.0 6.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) G3P_antiterm PF04309.12 EEQ32636.1 - 0.094 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Fes1 PF08609.10 EEQ32637.1 - 1.1e-28 99.9 5.8 2e-28 99.1 2.6 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 EEQ32637.1 - 3.1e-14 53.1 2.2 5e-07 30.0 0.2 2.2 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EEQ32637.1 - 4.4e-09 35.8 0.1 0.00031 20.7 0.0 2.9 3 0 0 3 3 2 2 HEAT repeat HEAT_EZ PF13513.6 EEQ32637.1 - 6.8e-09 36.1 0.1 2e-06 28.1 0.0 2.7 2 1 1 3 3 3 2 HEAT-like repeat Arm PF00514.23 EEQ32637.1 - 1.2e-06 28.3 0.0 0.027 14.5 0.0 2.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EEQ32637.1 - 0.0001 22.4 0.1 0.00024 21.2 0.0 1.7 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EEQ32637.1 - 0.00076 18.2 0.1 0.0016 17.1 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region SIL1 PF16782.5 EEQ32637.1 - 0.0039 16.5 0.0 0.17 11.1 0.0 2.2 1 1 1 2 2 2 1 Nucleotide exchange factor SIL1 RICTOR_V PF14668.6 EEQ32637.1 - 0.0047 17.1 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 TPR_18 PF13512.6 EEQ32637.1 - 0.013 15.6 0.1 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat V-ATPase_H_N PF03224.14 EEQ32637.1 - 0.023 14.0 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit H V-ATPase_H_C PF11698.8 EEQ32637.1 - 0.026 14.7 0.2 0.41 10.8 0.0 2.1 1 1 1 2 2 2 0 V-ATPase subunit H Actin PF00022.19 EEQ32638.1 - 4.1e-150 499.9 0.0 1.5e-149 498.1 0.0 1.7 1 1 0 1 1 1 1 Actin Glyco_hydro_18 PF00704.28 EEQ32639.1 - 8.6e-67 226.1 9.3 1.1e-66 225.7 9.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GARS_A PF01071.19 EEQ32640.1 - 1.3e-84 282.8 0.0 2.1e-84 282.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EEQ32640.1 - 3.2e-34 117.6 0.1 2.1e-33 115.0 0.0 2.5 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EEQ32640.1 - 1.2e-32 113.2 0.0 2.6e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EEQ32640.1 - 1e-25 89.8 1.4 2.5e-25 88.6 1.4 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EEQ32640.1 - 2.4e-14 53.7 1.9 7.4e-14 52.2 1.9 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 EEQ32640.1 - 0.00013 22.0 0.1 0.00045 20.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 EEQ32640.1 - 0.00021 20.9 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EEQ32640.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EEQ32640.1 - 0.0019 17.7 0.0 0.0043 16.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Pet127 PF08634.10 EEQ32641.1 - 6.4e-119 396.4 0.1 8.8e-119 396.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GIDA_assoc PF13932.6 EEQ32641.1 - 0.019 15.1 0.9 0.053 13.7 0.9 1.7 1 0 0 1 1 1 0 GidA associated domain Defensin_propep PF00879.18 EEQ32642.1 - 0.14 12.5 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Defensin propeptide LRR_6 PF13516.6 EEQ32643.1 - 1.9 8.7 6.0 29 5.1 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LHC PF00556.20 EEQ32644.1 - 0.15 12.3 0.5 0.32 11.3 0.4 1.6 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Gly_transf_sug PF04488.15 EEQ32645.1 - 2.2e-19 69.9 0.0 4e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Zn_peptidase_2 PF04298.12 EEQ32645.1 - 0.27 10.6 0.2 0.47 9.8 0.2 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Abhydrolase_6 PF12697.7 EEQ32646.1 - 1.7e-06 28.8 3.0 2.4e-06 28.3 3.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family RcsF PF16358.5 EEQ32646.1 - 0.16 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 RcsF lipoprotein Bul1_N PF04425.12 EEQ32648.1 - 3.3e-06 26.1 1.0 6.6e-05 21.8 0.2 2.1 1 1 1 2 2 2 2 Bul1 N terminus Arrestin_N PF00339.29 EEQ32648.1 - 0.00021 21.4 0.0 0.00066 19.7 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EEQ32648.1 - 0.0045 16.5 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 Bul1 C terminus Abhydrolase_1 PF00561.20 EEQ32649.1 - 0.0019 17.9 0.3 0.4 10.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ32649.1 - 0.017 14.6 0.0 0.061 12.8 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EEQ32649.1 - 0.018 15.7 0.5 0.034 14.8 0.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EEQ32649.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EEQ32649.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EEQ32649.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold AA_permease PF00324.21 EEQ32650.1 - 2e-139 465.3 46.1 2.5e-139 465.0 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ32650.1 - 1.8e-39 135.8 48.8 2.2e-39 135.5 48.8 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 EEQ32651.1 - 7.1e-20 71.2 26.9 8.9e-20 70.9 26.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Bacillus_PapR PF05968.11 EEQ32651.1 - 0.064 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacillus PapR protein p450 PF00067.22 EEQ32653.1 - 1.3e-59 202.2 0.0 1.7e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.20 EEQ32654.1 - 5.3e-15 56.2 0.0 1e-14 55.3 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 EEQ32654.1 - 6.4e-08 33.5 0.0 7.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ32654.1 - 0.0025 17.5 0.1 0.0067 16.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EEQ32654.1 - 0.0062 16.4 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Cytokin_check_N PF10407.9 EEQ32655.1 - 2.5e-05 24.1 0.0 5.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Pkinase PF00069.25 EEQ32656.1 - 2e-43 148.7 0.0 9.8e-32 110.4 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Ribonuc_2-5A PF06479.12 EEQ32656.1 - 3.9e-40 137.0 0.0 1.2e-39 135.4 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EEQ32656.1 - 8.2e-22 77.7 0.0 8.3e-19 67.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.21 EEQ32656.1 - 0.00016 21.5 0.1 0.12 12.4 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.14 EEQ32656.1 - 0.00067 19.1 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEQ32656.1 - 0.0018 17.1 0.0 0.0041 16.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EEQ32656.1 - 0.005 16.4 0.1 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL PQQ_2 PF13360.6 EEQ32656.1 - 0.0088 15.7 0.1 0.034 13.7 0.1 1.9 1 1 0 1 1 1 1 PQQ-like domain Pro_isomerase PF00160.21 EEQ32657.1 - 3.6e-51 173.6 0.0 7.5e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EEQ32657.1 - 2.9e-07 31.1 0.6 0.098 13.6 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 EEQ32658.1 - 1.2e-138 462.8 12.7 1.4e-138 462.6 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pam17 PF08566.10 EEQ32661.1 - 4.5e-67 225.0 0.1 6.1e-67 224.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Fungal_trans_2 PF11951.8 EEQ32662.1 - 3e-51 174.4 0.0 4.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ32662.1 - 7.3e-06 26.0 5.9 1.2e-05 25.3 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIB PF02201.18 EEQ32663.1 - 1.5e-27 95.2 0.1 3.9e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 EEQ32663.1 - 4.4e-15 55.3 0.2 9.5e-15 54.3 0.2 1.6 1 0 0 1 1 1 1 DEK C terminal domain Mcm10 PF09332.11 EEQ32663.1 - 0.01 15.3 2.3 0.012 15.0 2.3 1.2 1 0 0 1 1 1 0 Mcm10 replication factor CheR_N PF03705.15 EEQ32663.1 - 0.11 12.2 0.1 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain eIF2A PF08662.11 EEQ32664.1 - 1.3e-36 126.4 4.9 2.3e-34 119.0 1.0 3.9 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EEQ32664.1 - 3.7e-07 29.9 0.0 1e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP3 PF08572.10 EEQ32664.1 - 0.0027 17.5 0.1 0.0061 16.3 0.1 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) WD40 PF00400.32 EEQ32664.1 - 0.0065 17.3 1.8 0.22 12.4 0.1 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat DLH PF01738.18 EEQ32665.1 - 1.1e-25 90.5 0.0 1.4e-24 86.8 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family NmrA PF05368.13 EEQ32666.1 - 1.8e-12 47.4 0.0 2.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EEQ32666.1 - 1.2e-08 35.1 0.0 2.4e-08 34.1 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Peptidase_S10 PF00450.22 EEQ32667.1 - 4.8e-123 411.7 0.3 5.7e-123 411.4 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EEQ32667.1 - 0.00016 22.2 0.0 0.00048 20.7 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_1 PF00561.20 EEQ32668.1 - 2.8e-27 96.0 0.0 4.3e-27 95.4 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ32668.1 - 1.4e-09 37.6 0.0 2.7e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ32668.1 - 3.4e-06 27.8 0.1 5.1e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EEQ32668.1 - 0.024 14.8 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.14 EEQ32668.1 - 0.14 10.9 0.0 0.23 10.1 0.0 1.3 1 1 0 1 1 1 0 Ndr family Fungal_trans PF04082.18 EEQ32669.1 - 8.1e-18 64.4 4.4 8.1e-18 64.4 4.4 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EEQ32669.1 - 0.83 10.2 5.7 3.1 8.5 0.8 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Spt20 PF12090.8 EEQ32669.1 - 0.85 9.2 16.6 2.3 7.8 5.1 2.5 2 0 0 2 2 2 0 Spt20 family zf-C2H2_4 PF13894.6 EEQ32669.1 - 2.1 9.4 4.4 12 7.0 0.8 3.5 2 0 0 2 2 2 0 C2H2-type zinc finger RSN1_7TM PF02714.15 EEQ32670.1 - 2.7e-84 282.7 22.2 2.7e-84 282.7 22.2 2.3 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EEQ32670.1 - 1e-44 152.1 1.8 1e-44 152.1 1.8 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 EEQ32670.1 - 1.7e-26 92.2 0.1 4.3e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 EEQ32670.1 - 6.8e-25 88.3 0.0 1.1e-24 87.7 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF3593 PF12159.8 EEQ32670.1 - 2.5 8.2 8.9 1.3 9.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3593) Acyl_transf_1 PF00698.21 EEQ32671.1 - 3.7e-13 49.7 0.0 5.7e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Choline_kinase PF01633.20 EEQ32672.1 - 6e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EEQ32672.1 - 0.0018 18.2 0.0 0.0018 18.2 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ32672.1 - 0.02 14.2 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEQ32672.1 - 0.042 13.2 0.1 0.08 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein kinase domain Casc1_N PF15927.5 EEQ32672.1 - 0.64 9.7 11.6 1.5 8.5 11.6 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus zf-C3HC4_3 PF13920.6 EEQ32673.1 - 7.3e-07 28.9 9.4 7.3e-07 28.9 9.4 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ32673.1 - 3.9 7.4 20.6 0.046 13.6 10.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.21 EEQ32674.1 - 7.5e-61 205.5 1.2 1.2e-60 204.7 1.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.18 EEQ32674.1 - 1.2e-10 41.6 0.2 3.9e-10 39.9 0.2 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EEQ32674.1 - 2.3e-10 40.9 2.0 1.7e-09 38.0 0.2 2.5 2 0 0 2 2 2 1 MutS domain II MutS_III PF05192.18 EEQ32674.1 - 3.4e-09 37.2 7.4 7.7e-08 32.8 4.4 2.8 2 1 0 2 2 2 1 MutS domain III DUF3213 PF11491.8 EEQ32674.1 - 0.11 12.7 0.1 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) WD40 PF00400.32 EEQ32675.1 - 2.5e-50 167.4 29.4 3.8e-11 43.4 0.6 9.6 9 1 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ32675.1 - 1.6e-19 70.0 3.7 5.8e-05 23.3 0.1 5.5 3 3 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ32675.1 - 5.3e-06 26.5 0.1 0.15 11.9 0.1 3.6 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EEQ32675.1 - 5.1e-05 22.1 6.6 2.4 6.7 0.1 5.4 3 3 3 6 6 6 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ32675.1 - 0.00011 21.3 0.2 0.012 14.6 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 EEQ32675.1 - 0.00017 22.0 0.0 0.00035 21.0 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain DUF4550 PF15084.6 EEQ32675.1 - 0.0031 17.9 0.2 0.064 13.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4550) FAD_binding_9 PF08021.11 EEQ32675.1 - 0.037 14.3 0.2 19 5.5 0.0 3.8 3 2 1 4 4 4 0 Siderophore-interacting FAD-binding domain DUF3450 PF11932.8 EEQ32675.1 - 0.99 8.7 2.5 1.5 8.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) TFIIIC_delta PF12657.7 EEQ32675.1 - 2 8.3 8.5 5.8 6.8 1.1 3.7 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Sec10 PF07393.11 EEQ32676.1 - 1e-151 506.8 0.0 1.3e-151 506.5 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 EEQ32676.1 - 1.3e-07 31.4 0.0 2.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ32676.1 - 2.4e-05 24.1 0.1 4.8e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain RINT1_TIP1 PF04437.13 EEQ32676.1 - 0.029 13.3 0.0 0.13 11.1 0.0 1.9 2 0 0 2 2 2 0 RINT-1 / TIP-1 family AAA PF00004.29 EEQ32677.1 - 2.3e-29 102.5 0.0 3.7e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ32677.1 - 4.2e-06 27.2 0.0 9.7e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ32677.1 - 1.1e-05 25.7 0.0 4.9e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EEQ32677.1 - 3.6e-05 23.4 0.0 0.00063 19.4 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ32677.1 - 4.7e-05 24.0 0.0 8.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EEQ32677.1 - 5.5e-05 23.0 0.1 0.015 15.0 0.0 2.3 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EEQ32677.1 - 0.00046 20.5 0.0 0.0011 19.4 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.6 EEQ32677.1 - 0.00062 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EEQ32677.1 - 0.00068 19.6 0.1 0.0017 18.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EEQ32677.1 - 0.001 18.9 0.0 0.0026 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EEQ32677.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 EEQ32677.1 - 0.0039 17.4 0.0 0.0076 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EEQ32677.1 - 0.0046 17.0 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 EEQ32677.1 - 0.0053 16.9 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EEQ32677.1 - 0.0094 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EEQ32677.1 - 0.0095 15.7 0.1 0.04 13.6 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase ATPase_2 PF01637.18 EEQ32677.1 - 0.011 15.6 0.0 0.18 11.7 0.0 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EEQ32677.1 - 0.013 16.0 0.2 0.11 13.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EEQ32677.1 - 0.013 15.3 0.1 0.05 13.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEQ32677.1 - 0.02 14.3 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EEQ32677.1 - 0.031 13.4 0.0 0.066 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 EEQ32677.1 - 0.033 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EEQ32677.1 - 0.054 12.1 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EEQ32677.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_3 PF07726.11 EEQ32677.1 - 0.068 13.0 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EEQ32677.1 - 0.068 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 EEQ32677.1 - 0.069 13.5 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EEQ32677.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 EEQ32677.1 - 0.074 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EEQ32677.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DnaB_C PF03796.15 EEQ32677.1 - 0.11 11.8 0.0 0.37 10.1 0.0 1.6 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain Cytochrom_C1 PF02167.15 EEQ32678.1 - 5.5e-93 310.7 0.0 6.9e-93 310.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family SbcCD_C PF13558.6 EEQ32678.1 - 0.0029 17.8 0.2 0.0061 16.8 0.2 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Cytochrome_CBB3 PF13442.6 EEQ32678.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AIG2_2 PF13772.6 EEQ32679.1 - 6.2e-05 23.3 0.0 0.00028 21.2 0.0 2.0 2 0 0 2 2 2 1 AIG2-like family DAHP_synth_1 PF00793.20 EEQ32682.1 - 1.4e-103 345.5 0.0 1.8e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MFS_1 PF07690.16 EEQ32683.1 - 2.8e-09 36.4 33.8 2.8e-09 36.4 33.8 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF347 PF03988.12 EEQ32683.1 - 0.71 10.1 6.9 0.56 10.4 2.1 3.4 2 1 0 2 2 2 0 Repeat of Unknown Function (DUF347) RSN1_7TM PF02714.15 EEQ32684.1 - 5.8e-81 271.8 19.6 1.2e-80 270.7 19.6 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EEQ32684.1 - 2.8e-41 141.7 0.0 4.3e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EEQ32684.1 - 8.9e-35 119.8 0.4 8.9e-35 119.8 0.4 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 EEQ32684.1 - 0.0016 17.4 2.0 0.0016 17.4 2.0 2.3 2 0 0 2 2 2 1 Calcium-activated chloride channel DUF4293 PF14126.6 EEQ32684.1 - 0.83 9.9 0.0 0.83 9.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) hDGE_amylase PF14701.6 EEQ32685.1 - 5.2e-171 569.6 0.0 6.8e-171 569.2 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EEQ32685.1 - 7.9e-120 400.3 0.2 1.3e-119 399.6 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EEQ32685.1 - 3e-81 272.8 0.0 5.8e-81 271.9 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EEQ32685.1 - 2.6e-27 94.8 0.0 6.1e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 EEQ32685.1 - 0.011 15.4 0.0 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.23 EEQ32686.1 - 3.2e-45 153.9 0.0 5.3e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EEQ32686.1 - 3.2e-42 144.2 0.1 5.5e-42 143.4 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SLX9 PF15341.6 EEQ32687.1 - 9.6e-37 126.3 1.8 1.6e-36 125.6 1.8 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Pilin_GH PF16734.5 EEQ32687.1 - 0.0046 17.3 0.0 0.008 16.5 0.0 1.4 1 0 0 1 1 1 1 Type IV pilin-like G and H, putative ThiF PF00899.21 EEQ32688.1 - 5.9e-56 189.5 0.0 8.9e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EEQ32688.1 - 4.4e-06 27.2 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain NAD_binding_7 PF13241.6 EEQ32688.1 - 0.035 14.6 0.0 0.068 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding CdvA PF18822.1 EEQ32688.1 - 0.045 13.6 0.4 0.076 12.8 0.4 1.3 1 0 0 1 1 1 0 CdvA-like coiled-coil domain ApbA PF02558.16 EEQ32688.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EEQ32688.1 - 0.12 11.6 0.6 0.19 10.9 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EEQ32688.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EEQ32688.1 - 0.21 11.6 0.1 0.62 10.1 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FlxA PF14282.6 EEQ32688.1 - 0.39 10.7 3.3 0.65 10.0 3.3 1.3 1 0 0 1 1 1 0 FlxA-like protein DPBB_1 PF03330.18 EEQ32689.1 - 0.045 14.0 0.1 0.12 12.7 0.1 1.8 2 0 0 2 2 2 0 Lytic transglycolase NAD_binding_11 PF14833.6 EEQ32690.1 - 1.1e-44 151.6 0.6 1.8e-29 102.5 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EEQ32690.1 - 7.4e-36 123.7 0.0 1.3e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EEQ32690.1 - 0.0043 17.6 0.1 0.012 16.2 0.1 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EEQ32690.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EEQ32690.1 - 0.041 13.5 0.1 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F_bP_aldolase PF01116.20 EEQ32691.1 - 1.4e-80 270.8 0.0 1.6e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Fer2_3 PF13085.6 EEQ32692.1 - 1e-32 112.3 0.1 1.8e-32 111.6 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EEQ32692.1 - 9.9e-09 35.6 5.7 9.9e-09 35.6 5.7 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EEQ32692.1 - 1.7e-07 31.5 6.3 1.7e-07 31.5 6.3 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EEQ32692.1 - 8.4e-07 29.0 2.5 8.4e-07 29.0 2.5 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EEQ32692.1 - 0.0021 18.6 4.3 0.0021 18.6 4.3 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EEQ32692.1 - 0.0032 17.4 0.3 0.0032 17.4 0.3 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain RTA1 PF04479.13 EEQ32693.1 - 4.7e-73 245.2 4.9 5.8e-73 244.9 4.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3493 PF11998.8 EEQ32693.1 - 0.14 12.4 1.0 0.59 10.3 0.2 2.4 1 1 0 2 2 2 0 Low psii accumulation1 / Rep27 Abhydrolase_9_N PF15420.6 EEQ32693.1 - 0.14 12.1 1.5 0.24 11.4 1.1 1.5 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF4013 PF13197.6 EEQ32693.1 - 3.9 7.3 15.1 0.97 9.3 3.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4013) Velvet PF11754.8 EEQ32696.1 - 4e-51 174.4 0.0 4e-51 174.4 0.0 3.1 2 1 1 3 3 3 1 Velvet factor Zip PF02535.22 EEQ32696.1 - 0.0076 15.5 7.8 0.0088 15.3 7.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter AUX_IAA PF02309.16 EEQ32696.1 - 0.019 14.8 7.8 0.038 13.8 7.8 1.4 1 0 0 1 1 1 0 AUX/IAA family Ndc1_Nup PF09531.10 EEQ32696.1 - 0.02 13.6 7.6 0.022 13.5 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMR1 PF08505.10 EEQ32696.1 - 0.042 14.1 15.2 0.062 13.6 15.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein EPL1 PF10513.9 EEQ32696.1 - 0.094 13.1 11.4 0.14 12.5 11.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Tim54 PF11711.8 EEQ32696.1 - 0.37 9.5 8.9 0.6 8.8 8.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Exonuc_VII_L PF02601.15 EEQ32696.1 - 0.43 10.1 10.2 0.65 9.5 10.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 EEQ32696.1 - 0.49 9.7 13.7 0.68 9.2 13.7 1.1 1 0 0 1 1 1 0 FAM76 protein eIF-3_zeta PF05091.12 EEQ32696.1 - 0.67 8.9 11.6 0.89 8.5 11.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Otopetrin PF03189.13 EEQ32696.1 - 1.3 7.7 4.7 1.6 7.4 4.7 1.1 1 0 0 1 1 1 0 Otopetrin Presenilin PF01080.17 EEQ32696.1 - 1.9 7.1 14.6 2.6 6.7 14.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4770 PF15994.5 EEQ32696.1 - 2.4 8.4 16.8 4.1 7.6 16.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Gti1_Pac2 PF09729.9 EEQ32696.1 - 2.4 8.2 10.1 3.8 7.6 10.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 EEQ32696.1 - 2.5 7.0 10.6 3.6 6.5 10.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Ctr PF04145.15 EEQ32696.1 - 2.6 8.6 4.3 4.5 7.9 4.3 1.5 1 0 0 1 1 1 0 Ctr copper transporter family DUF3306 PF11748.8 EEQ32696.1 - 3.1 8.7 14.1 6.9 7.6 14.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Neur_chan_memb PF02932.16 EEQ32696.1 - 4.9 7.1 11.5 7.3 6.6 11.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TERB2 PF15101.6 EEQ32696.1 - 5.1 7.1 16.5 7.6 6.5 16.5 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PAT1 PF09770.9 EEQ32696.1 - 5.5 5.1 33.9 6.9 4.8 33.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 EEQ32696.1 - 5.6 6.7 11.6 7.8 6.2 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 EEQ32696.1 - 8.5 6.5 10.2 14 5.9 10.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Git3 PF11710.8 EEQ32697.1 - 3.7e-26 92.2 9.7 7.1e-26 91.2 9.7 1.4 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EEQ32697.1 - 1.1e-10 41.4 0.3 5.5e-10 39.2 0.0 2.4 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 EEQ32697.1 - 0.0047 16.1 7.1 0.0066 15.6 7.1 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor UPF0370 PF13980.6 EEQ32701.1 - 0.033 14.2 0.5 2.2 8.3 0.5 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) U6-snRNA_bdg PF10596.9 EEQ32701.1 - 0.05 13.6 3.1 1.9 8.4 0.3 2.4 2 0 0 2 2 2 0 U6-snRNA interacting domain of PrP8 HKR_ArcB_TM PF18415.1 EEQ32701.1 - 0.079 13.8 9.7 0.11 13.3 2.0 2.7 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Herpes_UL49_5 PF05702.11 EEQ32701.1 - 0.87 9.7 4.5 0.21 11.7 0.3 2.1 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein HhH-GPD PF00730.25 EEQ32703.1 - 7.9e-10 39.1 0.0 1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EEQ32703.1 - 0.0082 16.0 0.1 2.3 8.2 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 EEQ32703.1 - 0.11 13.1 0.0 8.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Fasciclin PF02469.22 EEQ32704.1 - 6.8e-26 91.0 0.3 1e-12 48.4 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain G_glu_transpept PF01019.21 EEQ32705.1 - 2.8e-169 564.2 0.0 3.2e-169 564.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AAA PF00004.29 EEQ32707.1 - 2.3e-45 154.3 0.2 7.5e-45 152.6 0.0 1.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EEQ32707.1 - 3e-10 39.9 0.1 2e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EEQ32707.1 - 6.5e-09 35.9 0.1 2.1e-08 34.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ32707.1 - 4.9e-08 33.3 0.0 9.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EEQ32707.1 - 1.3e-07 32.1 0.3 3.6e-05 24.2 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EEQ32707.1 - 3.5e-06 26.4 0.0 5.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EEQ32707.1 - 4e-05 23.9 1.2 0.0084 16.4 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EEQ32707.1 - 0.00022 21.0 0.0 0.00065 19.5 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EEQ32707.1 - 0.00036 20.3 0.0 0.00082 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 EEQ32707.1 - 0.00053 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EEQ32707.1 - 0.00059 19.4 0.1 0.0026 17.3 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 EEQ32707.1 - 0.00081 19.7 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEQ32707.1 - 0.0012 19.2 0.0 0.0037 17.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase TsaE PF02367.17 EEQ32707.1 - 0.0012 18.8 0.0 0.013 15.4 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EEQ32707.1 - 0.0018 17.6 0.0 0.0034 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EEQ32707.1 - 0.0021 18.1 0.0 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EEQ32707.1 - 0.0038 17.2 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 EEQ32707.1 - 0.0051 16.6 0.1 0.013 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EEQ32707.1 - 0.0055 16.6 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EEQ32707.1 - 0.0069 16.3 0.2 0.11 12.4 0.0 2.6 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 EEQ32707.1 - 0.0071 16.5 0.0 0.019 15.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 EEQ32707.1 - 0.0072 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EEQ32707.1 - 0.0084 15.5 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 EEQ32707.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EEQ32707.1 - 0.023 14.4 0.2 0.05 13.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EEQ32707.1 - 0.027 13.8 0.4 0.53 9.6 0.0 2.4 3 0 0 3 3 2 0 KaiC ATPase_2 PF01637.18 EEQ32707.1 - 0.033 14.1 0.1 0.32 10.9 0.0 2.2 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 EEQ32707.1 - 0.044 13.6 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 EEQ32707.1 - 0.061 12.9 0.4 0.24 10.9 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EEQ32707.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 EEQ32707.1 - 0.071 12.8 0.2 1.2 8.8 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EEQ32707.1 - 0.076 12.3 0.1 0.21 10.9 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AFG1_ATPase PF03969.16 EEQ32707.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_19 PF13245.6 EEQ32707.1 - 0.13 12.6 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EEQ32707.1 - 0.15 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EEQ32707.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 EEQ32707.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.23 EEQ32708.1 - 4.1e-102 341.8 0.6 4.9e-102 341.6 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEQ32708.1 - 2.6e-15 57.1 1.3 1.7e-12 48.0 1.3 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EEQ32708.1 - 6.2e-05 23.6 0.3 0.14 12.8 0.0 3.9 3 2 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EEQ32708.1 - 0.0063 17.0 0.0 2 9.0 0.0 3.3 3 2 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EEQ32708.1 - 0.011 15.5 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal gp45-slide_C PF09116.10 EEQ32708.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal NIF PF03031.18 EEQ32709.1 - 3.8e-27 95.0 0.0 7.4e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EEQ32709.1 - 1.7e-08 34.7 0.0 5.8e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EEQ32709.1 - 7.2e-08 32.7 0.2 3.6e-06 27.3 0.0 3.0 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EEQ32709.1 - 2.1e-05 24.3 0.7 4.4e-05 23.3 0.2 1.8 2 0 0 2 2 2 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 EEQ32709.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Biotin_lipoyl_2 PF13533.6 EEQ32709.1 - 0.017 14.9 0.0 7.5 6.5 0.0 2.7 2 0 0 2 2 2 0 Biotin-lipoyl like LIG3_BRCT PF16759.5 EEQ32709.1 - 0.034 14.4 0.1 0.083 13.2 0.1 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EEQ32709.1 - 0.14 12.3 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain MARVEL PF01284.23 EEQ32710.1 - 0.0014 18.7 18.7 0.0035 17.4 18.5 1.8 1 1 0 1 1 1 1 Membrane-associating domain Arginase PF00491.21 EEQ32711.1 - 2.3e-76 257.0 0.5 2.7e-76 256.8 0.5 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.15 EEQ32712.1 - 1.5e-94 316.4 0.0 2e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EEQ32712.1 - 9.4e-23 80.7 0.0 1.6e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 GatB domain ECH_1 PF00378.20 EEQ32716.1 - 7.9e-42 143.3 0.0 1.4e-41 142.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EEQ32716.1 - 1e-27 97.5 0.0 1.4e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pox_P21 PF05313.12 EEQ32716.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein NB-ARC PF00931.22 EEQ32718.1 - 2.6e-08 33.4 0.0 5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PGAP1 PF07819.13 EEQ32718.1 - 1.2e-07 31.7 0.1 2.5e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 EEQ32718.1 - 1.3e-05 25.6 0.0 4.1e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 EEQ32718.1 - 5.5e-05 22.8 0.5 0.00031 20.3 0.1 2.1 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EEQ32718.1 - 0.0038 17.9 0.1 0.018 15.7 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Zeta_toxin PF06414.12 EEQ32718.1 - 0.04 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF883 PF05957.13 EEQ32719.1 - 0.3 11.7 6.6 0.44 11.2 6.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EEQ32719.1 - 1.1 9.8 7.1 2 9.0 7.1 1.6 1 1 0 1 1 1 0 YtxH-like protein FHA PF00498.26 EEQ32720.1 - 4.4e-12 46.2 0.0 9.5e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain DnaJ PF00226.31 EEQ32721.1 - 4.4e-08 33.1 0.2 8.6e-08 32.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 EEQ32722.1 - 3.5e-26 92.1 0.0 2.6e-25 89.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32722.1 - 4.2e-15 55.7 0.0 6.9e-14 51.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ32722.1 - 4.2e-05 22.5 0.0 6.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEQ32722.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EEQ32722.1 - 0.03 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEQ32723.1 - 7.2e-10 39.2 0.0 1.8e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_3 PF07859.13 EEQ32725.1 - 1.2e-37 129.9 0.0 1.7e-36 126.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EEQ32725.1 - 0.0023 16.9 0.4 0.011 14.6 0.4 2.1 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF3944 PF13099.6 EEQ32726.1 - 0.31 11.0 3.2 0.68 9.8 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) CoA_transf_3 PF02515.17 EEQ32728.1 - 0.06 12.5 1.2 0.089 11.9 1.2 1.3 1 0 0 1 1 1 0 CoA-transferase family III HMG_box PF00505.19 EEQ32729.1 - 1.3e-24 86.4 0.5 2.2e-24 85.6 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EEQ32729.1 - 1.4e-18 67.2 0.9 2.3e-18 66.5 0.9 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EEQ32729.1 - 0.0011 19.5 0.0 0.0011 19.5 0.0 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 EEQ32729.1 - 0.0077 16.2 0.3 0.015 15.2 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 EEQ32729.1 - 0.043 13.8 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain p450 PF00067.22 EEQ32730.1 - 3.2e-40 138.3 0.0 4.4e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Homoserine_dh PF00742.19 EEQ32731.1 - 2e-52 177.6 0.0 2.6e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EEQ32731.1 - 1.4e-13 51.5 0.0 2.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.6 EEQ32732.1 - 8.2e-29 99.8 11.2 8.2e-29 99.8 11.2 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) ATG11 PF10377.9 EEQ32733.1 - 3.9e-45 153.1 0.1 3.9e-45 153.1 0.1 4.4 5 1 1 6 6 6 1 Autophagy-related protein 11 APG17 PF04108.12 EEQ32733.1 - 2e-11 43.7 6.8 1.5e-09 37.5 0.0 4.9 4 1 0 4 4 4 2 Autophagy protein Apg17 ERM PF00769.19 EEQ32733.1 - 0.00027 20.9 20.5 0.00027 20.9 20.5 6.2 4 2 0 5 5 5 1 Ezrin/radixin/moesin family DUF2570 PF10828.8 EEQ32733.1 - 0.0053 16.5 4.3 0.0053 16.5 4.3 4.7 3 2 1 4 4 4 1 Protein of unknown function (DUF2570) HSBP1 PF06825.12 EEQ32733.1 - 0.1 12.4 0.2 0.1 12.4 0.2 5.5 7 0 0 7 7 7 0 Heat shock factor binding protein 1 DUF3509 PF12021.8 EEQ32733.1 - 0.94 9.3 5.1 2.2 8.1 1.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3509) DUF496 PF04363.12 EEQ32733.1 - 4.9 7.2 12.1 0.18 11.8 0.3 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF496) Rnk_N PF14760.6 EEQ32733.1 - 9 6.9 14.4 0.24 11.9 2.1 4.5 4 0 0 4 4 4 0 Rnk N-terminus CENP-H PF05837.12 EEQ32734.1 - 7.2e-30 103.7 11.6 1e-29 103.2 6.0 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) SOAR PF16533.5 EEQ32734.1 - 0.021 14.8 6.1 0.52 10.3 1.9 2.3 2 0 0 2 2 2 0 STIM1 Orai1-activating region Ribosomal_L29 PF00831.23 EEQ32734.1 - 4.3 7.4 9.1 9.4 6.3 0.1 3.5 3 1 0 3 3 3 0 Ribosomal L29 protein Pex19 PF04614.12 EEQ32736.1 - 4.7e-73 246.0 13.3 4.7e-73 246.0 13.3 1.8 2 0 0 2 2 2 1 Pex19 protein family DUF4327 PF14217.6 EEQ32736.1 - 0.0029 17.7 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4327) Radial_spoke_3 PF06098.11 EEQ32736.1 - 0.0067 15.7 0.5 0.0067 15.7 0.5 2.3 2 1 1 3 3 3 1 Radial spoke protein 3 ASF1_hist_chap PF04729.13 EEQ32737.1 - 4.2e-74 247.6 0.0 6e-74 247.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 EEQ32737.1 - 1.6 6.8 23.0 2.1 6.5 23.0 1.0 1 0 0 1 1 1 0 Nop14-like family Rhabdo_ncap PF00945.18 EEQ32737.1 - 8 5.2 6.5 11 4.8 6.5 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Suf PF05843.14 EEQ32738.1 - 1.5e-95 320.6 0.0 1.5e-95 320.6 0.0 4.2 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EEQ32738.1 - 1.4e-05 25.5 0.0 0.056 14.3 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat HAT PF02184.16 EEQ32738.1 - 0.00069 19.5 0.1 0.0031 17.4 0.1 2.2 1 0 0 1 1 1 1 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 EEQ32738.1 - 0.0033 18.0 0.0 0.068 13.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Cdh1_DBD_1 PF18196.1 EEQ32738.1 - 0.071 13.4 2.5 0.18 12.1 2.5 1.6 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Oxysterol_BP PF01237.18 EEQ32739.1 - 1.4e-63 215.0 4.7 1.9e-61 208.0 4.7 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF2564 PF10819.8 EEQ32739.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) RTA1 PF04479.13 EEQ32740.1 - 7.9e-52 175.9 6.2 7.9e-52 175.9 6.2 1.7 2 0 0 2 2 2 1 RTA1 like protein CUE PF02845.16 EEQ32741.1 - 3e-10 39.6 0.0 5.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain UCH PF00443.29 EEQ32745.1 - 1.3e-35 123.1 0.2 5.4e-31 108.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ32745.1 - 5e-11 42.8 0.1 1e-09 38.5 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_4 PF13717.6 EEQ32745.1 - 1.7 8.6 8.5 6.4 6.8 0.7 2.6 2 0 0 2 2 2 0 zinc-ribbon domain F_bP_aldolase PF01116.20 EEQ32747.1 - 6.3e-91 304.7 0.0 7.2e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II RSN1_7TM PF02714.15 EEQ32751.1 - 1.9e-75 253.7 21.3 1.9e-75 253.7 21.3 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EEQ32751.1 - 5.9e-41 140.6 0.0 9.2e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EEQ32751.1 - 2.1e-40 138.0 0.8 2.1e-40 138.0 0.8 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Mfa_like_2 PF15415.6 EEQ32753.1 - 0.16 10.8 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Fimbrillin-like DUF3445 PF11927.8 EEQ32754.1 - 6.7e-59 199.3 0.0 9.4e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Mid2 PF04478.12 EEQ32755.1 - 0.0024 17.7 1.7 0.0025 17.7 0.1 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 EEQ32755.1 - 0.02 15.8 0.0 6.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Phage_holin_7_1 PF16081.5 EEQ32755.1 - 0.2 11.8 0.7 0.58 10.3 0.3 1.9 2 1 1 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family peroxidase PF00141.23 EEQ32756.1 - 1.7e-49 168.6 0.0 2.7e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ERG2_Sigma1R PF04622.12 EEQ32757.1 - 3.7e-77 258.4 0.1 4.2e-77 258.2 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein zf-CSL PF05207.13 EEQ32758.1 - 1e-17 63.6 0.2 1.6e-17 62.9 0.2 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EEQ32758.1 - 3.9e-12 46.1 1.8 2.4e-10 40.4 1.8 2.3 1 1 0 1 1 1 1 DnaJ domain PITH PF06201.13 EEQ32759.1 - 1.3e-37 129.3 0.0 1.9e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EEQ32759.1 - 4.8e-10 39.4 0.0 1.2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EEQ32759.1 - 0.0013 17.8 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosducin zf-C2H2 PF00096.26 EEQ32762.1 - 2.5e-12 46.5 13.1 1.4e-06 28.4 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ32762.1 - 2.8e-07 30.8 10.7 0.0064 17.2 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ32762.1 - 2.2e-06 27.8 3.2 0.012 15.9 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EEQ32762.1 - 3.8e-06 27.1 3.5 3.8e-06 27.1 3.5 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 EEQ32762.1 - 0.0011 19.2 10.2 0.0082 16.5 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 EEQ32762.1 - 0.0052 16.7 3.5 0.19 11.6 0.5 2.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 EEQ32762.1 - 0.02 14.9 0.7 0.02 14.9 0.7 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 EEQ32762.1 - 0.074 12.7 5.6 1.2 8.8 0.4 3.1 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-UBR PF02207.20 EEQ32762.1 - 0.12 12.5 0.7 0.28 11.4 0.7 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_3rep PF18868.1 EEQ32762.1 - 0.17 12.6 1.8 7.9 7.2 0.2 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-trcl PF13451.6 EEQ32762.1 - 0.82 9.6 4.2 0.84 9.6 0.6 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 EEQ32762.1 - 0.86 9.4 8.5 7.4 6.4 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EEQ32762.1 - 1.2 9.2 4.6 1 9.5 1.2 2.4 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 EEQ32762.1 - 3 8.0 4.4 6.7 6.9 0.6 2.3 1 1 1 2 2 2 0 Zinc ribbon domain DUF629 PF04780.12 EEQ32762.1 - 3.3 6.1 4.9 14 4.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2HE PF16278.5 EEQ32762.1 - 4.4 7.8 6.8 5.1e+02 1.2 6.9 2.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Diphthami_syn_2 PF01902.17 EEQ32763.1 - 6.4e-18 65.1 0.0 8.6e-06 25.4 0.0 4.1 3 1 1 4 4 4 4 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EEQ32763.1 - 4.2e-09 36.5 0.0 0.00018 21.5 0.0 3.4 3 1 0 3 3 3 2 Endoribonuclease L-PSP Pkinase PF00069.25 EEQ32764.1 - 2.1e-11 43.7 0.0 2.8e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32764.1 - 1.3e-09 37.8 0.0 4.3e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EEQ32764.1 - 4.2e-07 30.1 1.5 0.0014 18.6 0.9 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEQ32764.1 - 0.0021 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEQ32764.1 - 0.01 15.4 0.2 0.19 11.3 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase DHHC PF01529.20 EEQ32765.1 - 0.021 14.9 2.3 0.091 12.9 2.3 2.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3543 PF12063.8 EEQ32766.1 - 3.5e-96 321.4 0.3 5.5e-96 320.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EEQ32766.1 - 4.9e-63 212.9 0.0 9.4e-63 212.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32766.1 - 9.3e-42 143.1 0.0 2.4e-41 141.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ32766.1 - 0.083 12.8 0.2 0.23 11.3 0.2 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_2 PF13520.6 EEQ32767.1 - 1.9e-82 277.4 31.5 2.3e-82 277.1 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ32767.1 - 1.2e-16 60.4 28.7 1.5e-16 60.0 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease ERAP1_C PF11838.8 EEQ32768.1 - 1.7e-85 287.4 1.4 1.5e-83 280.9 0.0 2.5 2 1 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EEQ32768.1 - 5e-84 281.2 2.2 8e-84 280.6 2.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EEQ32768.1 - 1.3e-52 178.7 2.1 2.5e-52 177.8 2.1 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EEQ32768.1 - 0.095 12.7 0.3 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) DEAD PF00270.29 EEQ32769.1 - 3.2e-46 157.3 0.0 1.2e-45 155.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ32769.1 - 2.6e-18 66.4 0.9 3e-16 59.8 1.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ32769.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRAI PF00697.22 EEQ32769.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2986 PF11661.8 EEQ32769.1 - 2.4 8.8 10.1 0.17 12.4 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) p450 PF00067.22 EEQ32771.1 - 1.5e-21 76.8 0.2 3.4e-21 75.5 0.0 1.7 1 1 1 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.23 EEQ32772.1 - 1.4e-09 37.8 0.0 2.3e-08 33.9 0.0 2.6 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.12 EEQ32772.1 - 0.1 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like PNPase_C PF12111.8 EEQ32772.1 - 5.9 6.4 6.1 7.4 6.1 4.2 2.2 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal TPR_14 PF13428.6 EEQ32773.1 - 0.018 15.8 12.1 0.38 11.7 0.2 6.3 7 1 1 8 8 8 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 EEQ32773.1 - 0.02 15.1 0.3 2.4 8.5 0.1 2.7 2 0 0 2 2 2 0 c-SKI Smad4 binding domain DUF4810 PF16068.5 EEQ32773.1 - 0.024 15.2 0.2 3 8.4 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4810) Mitoc_mL59 PF18126.1 EEQ32774.1 - 1.6e-48 164.3 2.4 2.9e-48 163.4 2.4 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 MOSC PF03473.17 EEQ32775.1 - 7.7e-30 103.6 0.0 5.1e-29 100.9 0.0 2.1 2 0 0 2 2 2 1 MOSC domain Aminotran_5 PF00266.19 EEQ32775.1 - 1.3e-24 86.8 0.0 2.1e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 EEQ32775.1 - 5.3e-19 68.3 0.0 1e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MARVEL PF01284.23 EEQ32776.1 - 0.0093 16.0 9.8 0.012 15.6 9.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Kei1 PF08552.11 EEQ32776.1 - 0.046 13.6 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 EMC3_TMCO1 PF01956.16 EEQ32776.1 - 0.57 9.9 3.9 6.6 6.4 0.0 2.4 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SelK_SelG PF10961.8 EEQ32776.1 - 0.69 10.6 4.9 0.35 11.5 0.4 2.5 1 1 2 3 3 3 0 Selenoprotein SelK_SelG GcrA PF07750.11 EEQ32777.1 - 0.11 12.9 2.2 0.14 12.6 2.2 1.1 1 0 0 1 1 1 0 GcrA cell cycle regulator PAP2 PF01569.21 EEQ32778.1 - 2.4e-28 98.6 0.1 2.4e-28 98.6 0.1 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EEQ32778.1 - 0.00089 19.0 0.1 0.0033 17.1 0.1 1.9 1 1 0 1 1 1 1 PAP2 superfamily But2 PF09792.9 EEQ32780.1 - 2.2e-46 157.8 0.3 3.1e-46 157.3 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain NGP1NT PF08153.12 EEQ32782.1 - 3.5e-50 169.5 0.2 5.4e-50 168.9 0.2 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EEQ32782.1 - 2.8e-16 59.6 0.0 1.8e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ32782.1 - 2.3e-05 24.0 0.0 7e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEQ32782.1 - 0.01 15.7 0.0 0.074 13.0 0.0 2.2 1 1 0 1 1 1 0 RsgA GTPase Arf PF00025.21 EEQ32782.1 - 0.011 15.2 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 EEQ32782.1 - 0.032 14.3 0.5 0.82 9.7 0.0 3.0 3 1 1 4 4 4 0 Dynamin family Gpr1_Fun34_YaaH PF01184.19 EEQ32783.1 - 1.2e-55 188.4 11.3 1.6e-55 187.9 11.3 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2244 PF10003.9 EEQ32783.1 - 2.2 8.0 6.1 5 6.8 6.1 1.6 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF2207 PF09972.9 EEQ32783.1 - 7.6 5.2 12.0 10 4.8 8.7 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Methyltransf_23 PF13489.6 EEQ32784.1 - 2.2e-21 76.4 0.0 3.3e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ32784.1 - 4.7e-09 36.8 0.0 1.4e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ32784.1 - 2.5e-07 31.3 0.0 1.6e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ32784.1 - 1.3e-06 29.0 0.0 2.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ32784.1 - 1.4e-05 24.9 0.0 0.00012 21.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EEQ32784.1 - 3.8e-05 23.1 0.0 0.0028 17.0 0.0 2.8 3 0 0 3 3 3 1 O-methyltransferase domain Methyltransf_16 PF10294.9 EEQ32784.1 - 0.00029 20.6 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 EEQ32784.1 - 0.0069 15.9 0.0 0.091 12.2 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EEQ32784.1 - 0.013 15.1 0.0 0.031 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 EEQ32784.1 - 0.027 14.6 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase UPF0146 PF03686.13 EEQ32784.1 - 0.21 11.5 0.0 4 7.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) p450 PF00067.22 EEQ32785.1 - 1.5e-67 228.3 0.0 2e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EEQ32786.1 - 4.2e-44 151.1 0.0 5.2e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EEQ32787.1 - 1.8e-38 132.4 0.0 6.7e-38 130.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32787.1 - 1.9e-27 96.2 0.0 2.7e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ32787.1 - 0.00081 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEQ32787.1 - 0.0099 15.8 0.2 0.075 12.9 0.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ32787.1 - 0.032 13.5 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 EEQ32787.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prefoldin_3 PF13758.6 EEQ32788.1 - 3.3e-34 116.9 1.2 5.3e-34 116.2 0.1 2.0 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 EEQ32788.1 - 2.3e-25 89.3 0.2 2.3e-25 89.3 0.2 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3835) DUF1825 PF08855.10 EEQ32788.1 - 0.034 14.1 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) Lzipper-MIP1 PF14389.6 EEQ32788.1 - 0.23 11.8 4.4 8.9 6.7 0.4 3.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 ABC_tran_CTD PF16326.5 EEQ32788.1 - 3.1 8.1 6.0 4 7.8 0.3 3.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain Zip PF02535.22 EEQ32789.1 - 9.2e-37 127.0 20.9 9.2e-37 127.0 20.9 2.1 2 1 0 2 2 2 1 ZIP Zinc transporter Lactamase_B PF00753.27 EEQ32789.1 - 0.14 12.1 3.4 0.17 11.9 1.0 2.2 2 1 1 3 3 3 0 Metallo-beta-lactamase superfamily MAT1 PF06391.13 EEQ32790.1 - 1.5e-41 142.5 15.4 2e-41 142.1 15.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EEQ32790.1 - 1.9e-32 110.9 8.5 3.1e-32 110.2 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ32790.1 - 0.00014 21.7 5.1 0.00024 20.9 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ32790.1 - 0.0002 21.2 4.0 0.00053 19.8 4.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ32790.1 - 0.0014 18.4 4.1 0.003 17.4 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ32790.1 - 0.002 18.4 6.2 0.0034 17.7 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 EEQ32790.1 - 0.0099 15.7 5.0 0.07 12.9 1.9 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EEQ32790.1 - 0.015 14.9 1.3 0.031 13.9 1.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EEQ32790.1 - 0.031 14.2 7.3 0.27 11.2 7.9 2.1 1 1 1 2 2 2 0 zinc-RING finger domain DUF3797 PF12677.7 EEQ32790.1 - 0.066 13.1 2.3 0.15 12.0 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_UBOX PF13445.6 EEQ32790.1 - 0.39 10.8 6.8 0.8 9.8 6.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EEQ32790.1 - 1.7 8.6 8.2 55 3.7 9.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Presenilin PF01080.17 EEQ32790.1 - 4.4 6.0 7.0 6.4 5.4 7.0 1.2 1 0 0 1 1 1 0 Presenilin PRKG1_interact PF15898.5 EEQ32791.1 - 0.11 13.3 0.0 0.61 11.0 0.0 2.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.8 EEQ32791.1 - 0.12 12.6 1.0 0.42 10.8 1.0 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GIT_CC PF16559.5 EEQ32791.1 - 0.32 10.9 1.2 28 4.7 0.4 2.6 1 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 EEQ32791.1 - 0.36 10.6 2.9 6.9 6.4 2.8 2.6 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 EEQ32791.1 - 0.37 10.0 2.8 2.7 7.1 0.7 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region ATG16 PF08614.11 EEQ32791.1 - 0.7 10.1 4.7 1.7 8.9 4.7 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 EEQ32791.1 - 0.83 9.8 5.5 1.5 9.0 0.0 2.8 2 1 1 3 3 3 0 bZIP transcription factor DUF765 PF05570.11 EEQ32791.1 - 6.2 7.1 16.5 4.5 7.5 3.4 3.5 2 1 0 2 2 2 0 Circovirus protein of unknown function (DUF765) adh_short PF00106.25 EEQ32792.1 - 1.4e-24 86.7 0.0 1.9e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ32792.1 - 6.2e-13 48.8 0.0 9.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ32792.1 - 0.0026 17.7 0.1 0.0054 16.7 0.0 1.6 2 0 0 2 2 2 1 KR domain PEX11 PF05648.14 EEQ32794.1 - 6.1e-25 88.0 0.2 7.1e-25 87.8 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FMN_red PF03358.15 EEQ32795.1 - 9.8e-10 38.4 0.0 1.4e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EEQ32795.1 - 4.1e-08 33.2 0.0 7.3e-08 32.3 0.0 1.4 2 0 0 2 2 2 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EEQ32795.1 - 0.00013 22.2 0.1 0.0024 18.1 0.1 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EEQ32795.1 - 0.0014 18.9 0.0 0.0034 17.6 0.0 1.6 1 1 1 2 2 2 1 Flavodoxin domain NPL4 PF05021.15 EEQ32796.1 - 2.4e-139 464.0 0.0 3e-139 463.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EEQ32796.1 - 3.9e-68 228.2 0.1 6e-68 227.5 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EEQ32796.1 - 0.0065 16.9 0.0 0.029 14.8 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Kinesin PF00225.23 EEQ32797.1 - 6.4e-117 390.2 0.1 1.1e-116 389.5 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ32797.1 - 1.2e-26 93.5 2.2 1.8e-26 92.9 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Herpes_UL14 PF03580.14 EEQ32797.1 - 0.033 14.4 2.3 0.11 12.8 2.3 1.8 1 0 0 1 1 1 0 Herpesvirus UL14-like protein ING PF12998.7 EEQ32797.1 - 0.79 10.4 8.6 1.4 9.5 2.7 3.4 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding PRKG1_interact PF15898.5 EEQ32797.1 - 7.6 7.5 10.6 16 6.5 3.5 3.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Topoisom_bac PF01131.20 EEQ32798.1 - 1.2e-85 288.1 0.0 1.8e-77 261.1 0.0 3.0 2 1 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 EEQ32798.1 - 3.3e-10 40.1 0.0 8.3e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF3431 PF11913.8 EEQ32800.1 - 4.4e-90 301.2 0.4 5.2e-90 300.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) PhoR PF11808.8 EEQ32801.1 - 0.077 13.4 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Gemini_mov PF01708.16 EEQ32801.1 - 0.16 11.7 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein Tim17 PF02466.19 EEQ32802.1 - 0.00022 21.6 2.5 0.00022 21.6 2.5 1.6 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family cNMPbd_u2 PF16643.5 EEQ32804.1 - 6.2e-39 134.0 8.8 1.3e-38 132.9 8.8 1.5 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 EEQ32804.1 - 1.2e-34 118.3 0.0 5.5e-21 74.4 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 EEQ32804.1 - 3.5e-10 39.1 9.2 1.5 9.0 0.0 8.5 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 EEQ32804.1 - 1.9e-06 28.1 5.2 0.041 14.3 0.1 6.1 4 2 4 8 8 8 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EEQ32804.1 - 3.1e-06 27.0 0.5 3.1e-06 27.0 0.5 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EEQ32804.1 - 7.1e-05 22.6 1.3 7.1e-05 22.6 1.3 4.0 4 0 0 4 4 4 1 F-box domain LRR_1 PF00560.33 EEQ32804.1 - 0.0049 17.2 11.7 59 4.8 0.1 8.2 10 0 0 10 10 10 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 EEQ32804.1 - 0.079 13.2 3.5 9.3 6.6 0.5 4.2 4 1 0 4 4 4 0 Ste50p, sterile alpha motif Zn_clus PF00172.18 EEQ32805.1 - 8.1e-08 32.3 7.7 1.3e-07 31.6 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NRBF2 PF08961.10 EEQ32805.1 - 0.0073 15.9 0.2 0.0073 15.9 0.2 1.9 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 EEQ32805.1 - 0.021 15.4 0.1 0.057 14.0 0.1 1.7 1 0 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 EEQ32805.1 - 0.025 14.8 1.4 0.038 14.2 0.6 1.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper RasGAP_C PF03836.15 EEQ32805.1 - 0.027 14.6 0.2 0.071 13.3 0.2 1.7 1 1 0 1 1 1 0 RasGAP C-terminus DUF2205 PF10224.9 EEQ32805.1 - 0.038 14.0 1.7 0.046 13.7 0.0 2.0 2 0 0 2 2 2 0 Short coiled-coil protein DivIC PF04977.15 EEQ32805.1 - 0.26 11.1 0.1 0.26 11.1 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator PikAIV_N PF18605.1 EEQ32805.1 - 0.34 10.5 5.9 2.4 7.8 2.0 2.5 1 1 1 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ZapB PF06005.12 EEQ32805.1 - 0.35 11.4 5.3 2.3 8.7 5.3 2.3 1 1 0 1 1 1 0 Cell division protein ZapB XRCC4 PF06632.12 EEQ32805.1 - 0.44 9.4 6.7 4.1 6.2 0.0 2.3 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Slx4 PF09494.10 EEQ32806.1 - 6.8e-25 86.8 0.3 1.2e-24 86.0 0.3 1.5 1 0 0 1 1 1 1 Slx4 endonuclease CGI-121 PF08617.10 EEQ32807.1 - 7.5e-57 192.0 0.7 8.6e-57 191.8 0.7 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 baeRF_family11 PF18855.1 EEQ32807.1 - 0.067 13.5 0.7 10 6.4 0.0 3.7 1 1 4 5 5 5 0 Bacterial archaeo-eukaryotic release factor family 11 Bax1-I PF01027.20 EEQ32808.1 - 1.2e-32 113.4 10.9 1.2e-32 113.4 10.9 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Cutinase PF01083.22 EEQ32810.1 - 1.8e-36 125.7 0.0 2.5e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 EEQ32810.1 - 1.3e-05 25.2 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase LIP PF03583.14 EEQ32810.1 - 0.0011 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.20 EEQ32810.1 - 0.0014 18.3 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 EEQ32810.1 - 0.061 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 EEQ32810.1 - 0.089 13.4 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.11 EEQ32810.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain RRM_1 PF00076.22 EEQ32811.1 - 1e-15 57.3 0.0 1.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ32811.1 - 0.0043 16.6 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.14 EEQ32812.1 - 4.4e-22 79.1 2.1 2.9e-15 56.7 0.5 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 DUF1981 PF09324.10 EEQ32814.1 - 0.054 13.4 0.0 0.47 10.3 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) DUF2205 PF10224.9 EEQ32815.1 - 3e-34 116.8 0.9 4.7e-34 116.2 0.9 1.3 1 0 0 1 1 1 1 Short coiled-coil protein TPR_MLP1_2 PF07926.12 EEQ32815.1 - 0.0077 16.3 1.2 0.012 15.6 1.2 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein YabA PF06156.13 EEQ32815.1 - 0.0081 16.8 0.7 0.014 16.0 0.7 1.3 1 0 0 1 1 1 1 Initiation control protein YabA Tektin PF03148.14 EEQ32815.1 - 0.0087 14.9 0.8 0.012 14.3 0.8 1.2 1 0 0 1 1 1 1 Tektin family DivIC PF04977.15 EEQ32815.1 - 0.017 14.9 0.7 0.026 14.3 0.7 1.2 1 0 0 1 1 1 0 Septum formation initiator CASP_C PF08172.12 EEQ32815.1 - 0.017 14.5 1.3 0.017 14.5 1.3 2.0 2 0 0 2 2 2 0 CASP C terminal PI3K_P85_iSH2 PF16454.5 EEQ32815.1 - 0.019 14.5 0.8 0.025 14.2 0.8 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HALZ PF02183.18 EEQ32815.1 - 0.03 14.6 3.4 0.1 12.9 0.3 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF2884 PF11101.8 EEQ32815.1 - 0.035 13.6 0.5 0.046 13.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Prefoldin PF02996.17 EEQ32815.1 - 0.059 13.3 0.8 0.18 11.7 0.5 1.5 1 1 1 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.21 EEQ32815.1 - 0.11 12.6 1.8 1.6 8.9 0.4 2.0 1 1 1 2 2 2 0 bZIP transcription factor DUF5320 PF17253.2 EEQ32815.1 - 0.15 13.2 0.5 0.53 11.4 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) CCDC106 PF15794.5 EEQ32815.1 - 0.16 11.6 10.6 0.64 9.7 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 LCD1 PF09798.9 EEQ32815.1 - 0.22 10.0 1.7 0.29 9.6 1.7 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein ATG16 PF08614.11 EEQ32815.1 - 3 8.0 11.7 5.6 7.1 11.7 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) 14-3-3 PF00244.20 EEQ32816.1 - 1.1e-104 348.8 6.9 1.3e-104 348.5 6.9 1.1 1 0 0 1 1 1 1 14-3-3 protein IATP PF04568.12 EEQ32817.1 - 8.2e-25 87.1 0.4 9.2e-25 86.9 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Nsp1_C PF05064.13 EEQ32818.1 - 2.3e-29 101.5 5.0 2.3e-29 101.5 5.0 1.6 2 0 0 2 2 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EEQ32818.1 - 2.8e-10 40.9 114.0 5.4e-05 24.0 33.2 5.0 1 1 3 4 4 4 3 Nucleoporin FG repeat region HIP1_clath_bdg PF16515.5 EEQ32818.1 - 0.019 15.5 13.9 0.27 11.9 5.8 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ParB PF08775.10 EEQ32818.1 - 0.028 14.9 0.4 0.028 14.9 0.4 1.9 2 0 0 2 2 2 0 ParB family DUF4200 PF13863.6 EEQ32818.1 - 0.047 14.1 7.0 0.052 14.0 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EEQ32818.1 - 0.12 12.5 4.8 1.3 9.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 EEQ32818.1 - 0.21 11.9 7.8 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 EEQ32818.1 - 0.22 10.4 10.9 0.054 12.4 3.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 EEQ32818.1 - 0.24 10.7 6.7 0.41 10.0 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 EEQ32818.1 - 0.25 11.6 3.1 5.3 7.4 0.1 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 EEQ32818.1 - 0.33 11.4 7.6 0.76 10.2 0.4 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 EEQ32818.1 - 0.48 10.5 6.0 1.5 8.9 6.0 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 EEQ32818.1 - 0.81 8.2 7.4 1.8 7.1 7.4 1.4 1 1 0 1 1 1 0 AAA domain V-SNARE PF05008.15 EEQ32818.1 - 1.1 9.6 7.6 0.91 9.9 0.8 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus CREPT PF16566.5 EEQ32818.1 - 1.5 8.9 5.4 0.64 10.2 0.8 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FliT PF05400.13 EEQ32818.1 - 1.6 9.6 5.8 0.91 10.4 0.9 2.6 1 1 1 2 2 2 0 Flagellar protein FliT FapA PF03961.13 EEQ32818.1 - 1.8 7.1 4.4 2.4 6.7 0.2 2.0 1 1 2 3 3 3 0 Flagellar Assembly Protein A CK2S PF15011.6 EEQ32818.1 - 2 8.3 7.8 1.4 8.8 3.4 2.2 2 0 0 2 2 2 0 Casein Kinase 2 substrate Occludin_ELL PF07303.13 EEQ32818.1 - 2.4 8.9 4.6 4.2 8.2 1.6 2.2 2 0 0 2 2 2 0 Occludin homology domain Laminin_II PF06009.12 EEQ32818.1 - 2.5 8.1 11.0 2.6 8.1 2.5 2.2 1 1 0 2 2 2 0 Laminin Domain II GAT PF03127.14 EEQ32818.1 - 2.8 8.3 5.1 9.8 6.6 0.2 2.4 1 1 1 2 2 2 0 GAT domain BLOC1_2 PF10046.9 EEQ32818.1 - 3.6 8.0 6.8 14 6.0 1.2 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRE1 PF08647.11 EEQ32818.1 - 3.9 7.6 8.5 7.5 6.7 4.0 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 EEQ32818.1 - 6.3 6.9 17.1 4.1 7.5 9.6 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 EEQ32818.1 - 6.5 6.5 8.9 0.53 10.1 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF5102 PF17104.5 EEQ32819.1 - 1.6e-114 382.8 1.4 1.6e-114 382.8 1.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5102) DUF4543 PF15076.6 EEQ32819.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) Clathrin_bdg PF15045.6 EEQ32819.1 - 0.079 13.0 0.0 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking zf-MIZ PF02891.20 EEQ32820.1 - 8.8e-11 41.4 0.2 1.8e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PH PF00169.29 EEQ32822.1 - 6e-10 39.6 0.2 5.7e-09 36.4 0.2 2.4 1 1 0 1 1 1 1 PH domain SH3_1 PF00018.28 EEQ32822.1 - 1.9e-09 37.0 0.0 3.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ32822.1 - 7.1e-09 35.4 0.1 1.5e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 EEQ32822.1 - 1.5e-08 34.6 0.1 3e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 EEQ32822.1 - 0.00022 20.8 0.1 0.00046 19.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 EEQ32822.1 - 0.0006 20.2 0.0 0.0017 18.8 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.30 EEQ32822.1 - 0.0016 18.9 0.1 0.003 18.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 EEQ32822.1 - 0.037 14.3 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Ribosomal_L14 PF00238.19 EEQ32824.1 - 8.6e-34 116.3 0.0 1e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 EEQ32824.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Hist_deacetyl PF00850.19 EEQ32825.1 - 1.8e-77 260.9 0.0 3.5e-77 259.9 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 EEQ32826.1 - 2.2e-33 114.7 0.0 5e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EEQ32826.1 - 9.2e-12 45.4 0.9 1.5e-11 44.7 0.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EEQ32826.1 - 4.7e-07 29.6 0.0 3.6e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain NIF PF03031.18 EEQ32828.1 - 1.5e-40 138.5 0.0 2.1e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Beta_elim_lyase PF01212.21 EEQ32829.1 - 4.8e-57 193.5 0.0 6.7e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.18 EEQ32830.1 - 3.1e-16 59.2 0.0 1.1e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ32830.1 - 2.4e-06 27.6 6.3 4.7e-06 26.6 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EEQ32831.1 - 8.4e-06 25.6 1.1 1.8e-05 24.5 1.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ32831.1 - 0.00037 20.3 0.9 0.00081 19.2 0.9 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EEQ32831.1 - 0.11 13.4 0.1 78 4.4 0.1 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat GRDP-like PF07173.12 EEQ32832.1 - 5.9e-16 59.4 0.8 2e-12 48.0 0.0 2.7 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Fungal_trans PF04082.18 EEQ32833.1 - 4.4e-08 32.5 0.5 4.4e-08 32.5 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.25 EEQ32835.1 - 2.5e-72 243.4 0.0 4.1e-72 242.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32835.1 - 2.8e-38 131.7 0.0 6.5e-38 130.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ32835.1 - 0.0018 17.6 0.1 1.5 8.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EEQ32835.1 - 0.054 13.4 0.5 1.7 8.5 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEQ32835.1 - 0.083 11.6 0.0 0.37 9.5 0.0 2.0 2 1 1 3 3 3 0 Fungal protein kinase MFS_1 PF07690.16 EEQ32836.1 - 2.8e-30 105.4 31.1 3.5e-19 69.0 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ32836.1 - 2.6e-20 72.7 14.5 2.1e-19 69.7 14.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ32838.1 - 6.1e-30 104.3 60.0 1.2e-28 100.1 39.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ32838.1 - 1.6e-10 40.5 36.0 1e-06 27.9 14.1 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter zf-LITAF-like PF10601.9 EEQ32839.1 - 7 7.0 12.5 1.7 8.9 0.5 3.1 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain HAMP PF00672.25 EEQ32840.1 - 2.6e-36 123.7 16.0 6.6e-08 32.8 0.5 7.8 6 2 2 8 8 8 5 HAMP domain HATPase_c PF02518.26 EEQ32840.1 - 2.8e-33 114.7 0.0 1.5e-32 112.4 0.0 2.3 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EEQ32840.1 - 1e-24 86.8 1.2 5.9e-24 84.4 0.5 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EEQ32840.1 - 6.5e-17 61.3 4.1 2.2e-16 59.6 0.1 3.9 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 EEQ32840.1 - 7.2e-11 41.8 5.2 0.2 10.7 0.3 5.7 1 1 3 5 5 5 4 Autophagy protein Apg17 DUF4279 PF14106.6 EEQ32840.1 - 8.9e-06 25.9 0.0 3.5 7.9 0.0 5.5 5 1 0 5 5 5 1 Domain of unknown function (DUF4279) DUF3829 PF12889.7 EEQ32840.1 - 0.0016 17.9 14.8 0.037 13.5 0.3 5.0 5 1 1 6 6 6 2 Protein of unknown function (DUF3829) Syntaxin_2 PF14523.6 EEQ32840.1 - 0.0019 18.5 15.4 5.9 7.3 0.0 6.8 3 2 4 7 7 7 1 Syntaxin-like protein DUF948 PF06103.11 EEQ32840.1 - 0.0019 18.4 48.1 1.3 9.3 0.1 9.1 3 1 1 5 5 4 1 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EEQ32840.1 - 0.031 14.5 32.0 2.6 8.3 0.1 7.3 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family NOD PF06816.13 EEQ32840.1 - 0.047 13.3 0.0 6 6.6 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein IcmF_C PF06744.12 EEQ32840.1 - 0.058 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal Vps52 PF04129.12 EEQ32840.1 - 0.062 12.0 4.4 4.8 5.8 0.2 3.8 4 0 0 4 4 4 0 Vps52 / Sac2 family SpoIIID PF12116.8 EEQ32840.1 - 0.1 12.7 2.8 25 5.1 0.1 4.5 4 0 0 4 4 3 0 Stage III sporulation protein D Gp-FAR-1 PF05823.12 EEQ32840.1 - 0.12 12.7 4.6 41 4.5 0.0 4.7 1 1 3 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4795 PF16043.5 EEQ32840.1 - 0.34 10.5 25.2 0.44 10.1 1.9 5.1 1 1 4 5 5 5 0 Domain of unknown function (DUF4795) WXG100 PF06013.12 EEQ32840.1 - 0.44 10.8 19.6 11 6.3 0.2 7.1 6 2 1 7 7 7 0 Proteins of 100 residues with WXG CMD PF02627.20 EEQ32840.1 - 0.55 10.3 2.2 8.5 6.5 0.1 3.7 4 0 0 4 4 4 0 Carboxymuconolactone decarboxylase family DUF2877 PF11392.8 EEQ32840.1 - 1.2 9.9 9.0 11 6.8 0.2 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2877) CENP-F_leu_zip PF10473.9 EEQ32840.1 - 2.4 8.2 27.9 3.5 7.7 0.2 7.5 5 3 1 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GLE1 PF07817.13 EEQ32840.1 - 3.1 6.9 11.2 19 4.3 0.4 4.4 3 1 2 5 5 5 0 GLE1-like protein GhoS PF11080.8 EEQ32840.1 - 3.4 7.7 7.4 4.2 7.4 0.1 3.9 4 0 0 4 4 4 0 Endoribonuclease GhoS AdHead_fibreRBD PF16812.5 EEQ32840.1 - 3.5 7.4 11.8 0.046 13.6 0.4 3.3 4 0 0 4 4 4 0 C-terminal head domain of the fowl adenovirus type 1 long fibre tRNA-synt_2d PF01409.20 EEQ32841.1 - 4.5e-88 294.9 0.0 5.9e-88 294.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EEQ32841.1 - 4.2e-16 59.0 0.7 1.3e-15 57.4 0.2 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 EEQ32841.1 - 7.3e-05 22.0 0.2 0.0037 16.4 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 EEQ32841.1 - 0.00035 20.1 0.0 0.21 11.0 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EEQ32841.1 - 0.0012 18.8 0.7 0.0032 17.4 0.7 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 DUF2564 PF10819.8 EEQ32841.1 - 0.077 13.4 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) Ribosomal_S21e PF01249.18 EEQ32842.1 - 5.3e-42 141.8 0.0 5.9e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.28 EEQ32843.1 - 6.9e-07 29.4 0.0 1.9e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain Dpy19 PF10034.9 EEQ32843.1 - 0.23 9.6 0.0 0.29 9.3 0.0 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation IMPDH PF00478.25 EEQ32844.1 - 4.3e-129 430.5 5.9 5.1e-129 430.2 5.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EEQ32844.1 - 1.2e-18 67.3 0.1 1.5e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EEQ32844.1 - 5.2e-08 32.3 0.9 1.3e-07 31.0 0.9 1.7 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EEQ32844.1 - 3.3e-07 30.0 8.6 0.0029 17.0 6.9 2.9 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 EEQ32844.1 - 2.1e-05 24.1 1.2 4.3e-05 23.1 1.2 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.21 EEQ32844.1 - 0.002 17.1 0.0 0.0038 16.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Aldolase PF01081.19 EEQ32844.1 - 0.03 13.8 1.7 0.17 11.2 0.2 2.4 1 1 0 2 2 2 0 KDPG and KHG aldolase ThiG PF05690.14 EEQ32844.1 - 0.031 13.6 0.5 0.031 13.6 0.5 1.8 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG EAL PF00563.20 EEQ32844.1 - 0.074 12.6 0.4 14 5.1 0.1 2.5 2 1 0 2 2 2 0 EAL domain YpsA PF06908.11 EEQ32844.1 - 0.076 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Glu_synthase PF01645.17 EEQ32844.1 - 0.085 12.0 3.9 0.18 10.9 3.9 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase G3P_antiterm PF04309.12 EEQ32844.1 - 1.1 8.7 3.5 2.7 7.4 0.2 2.5 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator DUF4807 PF16065.5 EEQ32845.1 - 0.059 13.0 0.3 0.37 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4807) Pkinase PF00069.25 EEQ32845.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RasGAP PF00616.19 EEQ32846.1 - 2.3e-52 177.8 0.0 5.9e-52 176.4 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EEQ32846.1 - 6.1e-50 168.9 5.9 6.1e-50 168.9 5.9 2.5 2 0 0 2 2 2 1 RasGAP C-terminus CH PF00307.31 EEQ32846.1 - 2.9e-13 49.9 0.0 2.8e-12 46.8 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 EEQ32846.1 - 7.2e-10 37.8 41.9 0.41 10.6 0.0 15.4 17 0 0 17 17 17 4 IQ calmodulin-binding motif CAMSAP_CH PF11971.8 EEQ32846.1 - 0.044 13.6 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 CAMSAP CH domain IZUMO PF15005.6 EEQ32846.1 - 0.089 13.3 3.2 0.13 12.8 0.2 2.9 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated ENTH PF01417.20 EEQ32847.1 - 2.1e-44 150.5 0.1 4e-44 149.7 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EEQ32847.1 - 0.0038 16.3 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain SH3_1 PF00018.28 EEQ32848.1 - 2.9e-11 42.8 0.0 5.4e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ32848.1 - 5.5e-09 35.8 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ32848.1 - 4e-07 29.6 0.0 7.1e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 EEQ32849.1 - 3.5e-23 82.1 50.0 1.2e-12 47.4 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM_GPCR_Srh PF10318.9 EEQ32849.1 - 3e-05 23.2 0.9 3e-05 23.2 0.9 2.5 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srh MFS_1_like PF12832.7 EEQ32849.1 - 0.76 8.6 27.8 0.64 8.8 11.5 2.8 1 1 1 2 2 2 0 MFS_1 like family DUF4011 PF13195.6 EEQ32851.1 - 0.061 13.3 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) HMG-CoA_red PF00368.18 EEQ32852.1 - 6e-137 456.5 10.2 1.1e-136 455.7 10.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EEQ32852.1 - 2.7e-46 157.3 0.0 5e-46 156.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EEQ32852.1 - 3.6e-11 43.1 6.6 5.3e-10 39.3 6.6 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EEQ32852.1 - 2.8e-05 22.4 1.0 2.8e-05 22.4 1.0 1.3 2 0 0 2 2 2 1 Patched family CVNH PF08881.10 EEQ32853.1 - 2.6e-23 82.6 0.1 3e-23 82.4 0.1 1.0 1 0 0 1 1 1 1 CVNH domain GIT_SHD PF08518.11 EEQ32854.1 - 2.3e-21 75.1 12.8 2e-11 43.3 1.2 3.0 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT APG6_N PF17675.1 EEQ32854.1 - 0.018 15.6 9.2 0.018 15.6 9.2 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region GIT1_C PF12205.8 EEQ32854.1 - 0.058 13.5 0.8 0.38 10.9 0.1 2.7 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Pro_isomerase PF00160.21 EEQ32855.1 - 4.7e-44 150.4 0.1 5.5e-44 150.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_PH PF01138.21 EEQ32856.1 - 1.2e-33 116.4 0.2 1.8e-33 115.9 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SNF2_N PF00176.23 EEQ32857.1 - 4.4e-53 180.2 0.0 6.9e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EEQ32857.1 - 1.4e-26 92.3 0.6 3.6e-26 91.1 0.6 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EEQ32857.1 - 2.6e-19 69.6 0.0 1.8e-18 66.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EEQ32857.1 - 3e-08 33.2 0.0 5.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EEQ32857.1 - 7.8e-07 29.3 0.0 2.8e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEQ32857.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase IcmF_C PF06744.12 EEQ32857.1 - 0.037 13.7 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal Troponin-I_N PF11636.8 EEQ32857.1 - 0.084 12.8 0.1 0.28 11.2 0.1 1.9 1 0 0 1 1 1 0 Troponin I residues 1-32 Ssu72 PF04722.13 EEQ32858.1 - 6.1e-82 273.8 0.0 7.1e-82 273.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.11 EEQ32858.1 - 2 8.4 6.0 3.1 7.8 6.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 EEQ32858.1 - 2.8 8.0 9.7 4.9 7.2 9.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EEQ32858.1 - 4.5 6.7 11.8 7.3 6.0 11.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2946 PF11162.8 EEQ32859.1 - 0.001 19.7 4.3 0.14 12.8 0.5 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2946) Trypan_PARP PF05887.11 EEQ32859.1 - 0.12 12.3 10.4 0.028 14.4 4.4 2.7 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) PyrI_C PF02748.15 EEQ32859.1 - 0.2 11.6 2.0 4.9 7.1 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CpXC PF14353.6 EEQ32859.1 - 0.28 11.2 1.5 12 6.0 0.1 2.6 2 0 0 2 2 2 0 CpXC protein zf-CHCC PF10276.9 EEQ32859.1 - 0.57 10.3 5.8 11 6.2 1.2 2.8 2 0 0 2 2 2 0 Zinc-finger domain Acyl-CoA_dh_1 PF00441.24 EEQ32860.1 - 1.4e-17 64.3 0.3 9.2e-17 61.6 0.3 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 EEQ32860.1 - 1.2e-12 48.0 0.0 2.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 EEQ32860.1 - 3.9e-10 39.8 0.0 9.5e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AcylCoA_dehyd_C PF12186.8 EEQ32860.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal TORC_M PF12885.7 EEQ32860.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Oxysterol_BP PF01237.18 EEQ32861.1 - 2.1e-69 234.2 5.1 9.2e-52 176.1 0.0 3.1 1 1 2 3 3 3 3 Oxysterol-binding protein APH PF01636.23 EEQ32862.1 - 1.7e-05 24.9 0.1 2.5e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3605 PF12239.8 EEQ32863.1 - 1e-57 194.8 1.4 1.3e-57 194.5 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.20 EEQ32864.1 - 2.2e-26 93.1 0.0 3.9e-21 76.0 0.0 2.0 2 0 0 2 2 2 2 Isochorismatase family Hist_deacetyl PF00850.19 EEQ32865.1 - 4.9e-78 262.7 0.0 6.4e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.7 EEQ32866.1 - 5.1e-22 78.4 4.8 8.7e-22 77.6 4.8 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EEQ32866.1 - 2.8e-05 23.9 9.7 5.3e-05 23.0 9.7 1.5 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.13 EEQ32866.1 - 0.003 17.6 9.0 0.0047 17.0 9.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Prominin PF05478.11 EEQ32866.1 - 0.057 11.4 0.4 0.078 10.9 0.4 1.1 1 0 0 1 1 1 0 Prominin Hamartin PF04388.12 EEQ32866.1 - 0.54 8.9 13.2 0.8 8.3 13.2 1.2 1 0 0 1 1 1 0 Hamartin protein RNA_pol_Rpc34 PF05158.12 EEQ32867.1 - 1.4e-107 360.0 0.0 1.6e-107 359.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.20 EEQ32867.1 - 0.2 12.0 0.1 0.89 9.9 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator TPR_1 PF00515.28 EEQ32868.1 - 4.9e-39 130.6 21.8 2.1e-05 24.1 0.0 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 EEQ32868.1 - 1.7e-36 123.9 7.5 3.5e-20 71.7 0.7 2.9 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 EEQ32868.1 - 2.5e-30 102.1 21.2 0.00026 20.9 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ32868.1 - 1.4e-17 63.1 14.6 0.0042 16.7 0.0 7.9 6 1 2 8 8 8 4 TPR repeat TPR_8 PF13181.6 EEQ32868.1 - 1e-15 56.5 21.1 0.0072 16.5 0.1 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ32868.1 - 1.8e-15 57.2 17.6 0.0034 17.8 0.1 6.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ32868.1 - 1.8e-11 44.5 12.8 0.011 16.3 0.1 6.5 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ32868.1 - 4.5e-10 39.5 4.2 0.0021 18.2 0.1 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ32868.1 - 5.1e-10 39.5 18.5 0.016 15.5 0.5 6.4 5 3 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ32868.1 - 3.8e-08 33.5 20.0 1.7 9.7 0.2 9.2 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ32868.1 - 6.7e-08 32.4 9.4 0.11 12.9 0.0 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ32868.1 - 9.1e-08 31.6 11.2 0.0088 16.0 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ32868.1 - 0.00011 21.9 8.3 0.89 9.5 0.0 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ32868.1 - 0.00086 19.5 7.1 0.26 11.5 0.2 3.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EEQ32868.1 - 0.0097 16.5 19.6 2.9 8.7 0.0 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat Inhibitor_I9 PF05922.16 EEQ32868.1 - 0.056 14.1 0.0 0.26 12.0 0.0 2.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 DUF627 PF04781.12 EEQ32868.1 - 0.78 9.8 8.5 2.5 8.2 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF627) SPESP1 PF15754.5 EEQ32868.1 - 1 8.5 5.8 0.13 11.4 1.2 1.8 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 SHNi-TPR PF10516.9 EEQ32868.1 - 1.1 8.8 8.4 20 4.7 0.1 5.6 6 0 0 6 6 6 0 SHNi-TPR C2 PF00168.30 EEQ32869.1 - 2.3e-72 239.8 0.3 2.4e-18 66.3 0.1 5.4 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EEQ32869.1 - 0.084 12.3 0.0 0.45 10.0 0.0 2.0 1 1 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain RRM_1 PF00076.22 EEQ32870.1 - 2.8e-17 62.3 0.0 4.9e-12 45.5 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EEQ32870.1 - 0.055 13.5 0.0 0.49 10.4 0.0 2.5 2 1 0 2 2 2 0 DbpA RNA binding domain Limkain-b1 PF11608.8 EEQ32870.1 - 0.076 13.1 0.0 1.4 9.1 0.0 2.7 2 1 0 2 2 2 0 Limkain b1 RRM_5 PF13893.6 EEQ32870.1 - 0.087 12.4 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UDPGP PF01704.18 EEQ32871.1 - 3.4e-189 628.7 0.0 4e-189 628.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 EEQ32871.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilO DUF3915 PF13054.6 EEQ32872.1 - 1.9 8.5 7.1 6.1 6.9 7.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) zf-CCCH PF00642.24 EEQ32873.1 - 3.3e-08 33.2 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EEQ32873.1 - 0.00043 20.0 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EEQ32873.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 EEQ32873.1 - 0.083 13.6 6.7 0.5 11.1 0.2 2.6 3 0 0 3 3 3 0 Torus domain DUF4185 PF13810.6 EEQ32874.1 - 0.002 17.4 0.1 0.0044 16.3 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4185) Spa1_C PF18218.1 EEQ32874.1 - 0.045 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Lantibiotic immunity protein Spa1 C-terminal domain TetR_C_32 PF09209.11 EEQ32874.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Kelch_6 PF13964.6 EEQ32874.1 - 0.078 13.3 0.0 0.26 11.6 0.0 2.0 1 0 0 1 1 1 0 Kelch motif DUF823 PF05689.11 EEQ32874.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) Amidase PF01425.21 EEQ32875.1 - 2e-87 294.0 0.0 3.2e-87 293.4 0.0 1.3 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 EEQ32876.1 - 1.2e-15 57.3 22.5 1.2e-15 57.3 22.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DoxX_3 PF13781.6 EEQ32876.1 - 3.1 8.5 8.1 0.12 13.0 0.6 2.6 3 0 0 3 3 3 0 DoxX-like family PhyH PF05721.13 EEQ32877.1 - 2.2e-28 100.0 0.0 2.7e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Epimerase PF01370.21 EEQ32878.1 - 3.6e-05 23.4 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 EEQ32879.1 - 8.7e-06 25.8 12.6 1.5e-05 25.0 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ32879.1 - 0.00041 19.5 0.0 0.00077 18.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GAPT PF11770.8 EEQ32879.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) FYVE PF01363.21 EEQ32880.1 - 7.3e-20 70.9 2.4 7.3e-20 70.9 2.4 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 EEQ32880.1 - 7.3e-08 32.6 4.2 7.3e-08 32.6 4.2 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ32880.1 - 3.5e-06 26.7 2.7 3.5e-06 26.7 2.7 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEQ32880.1 - 9.7e-05 22.0 4.5 9.7e-05 22.0 4.5 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 EEQ32880.1 - 0.0012 19.0 2.1 0.0012 19.0 2.1 3.8 4 0 0 4 4 4 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EEQ32880.1 - 0.003 17.4 2.9 0.003 17.4 2.9 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ32880.1 - 0.013 15.5 3.1 0.013 15.5 3.1 3.8 3 0 0 3 3 3 0 RING-type zinc-finger RNF220 PF15926.5 EEQ32880.1 - 0.089 12.4 0.9 5.9 6.4 0.0 2.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 RINGv PF12906.7 EEQ32880.1 - 0.25 11.5 8.5 0.42 10.8 4.8 2.7 2 0 0 2 2 2 0 RING-variant domain FYVE_2 PF02318.16 EEQ32880.1 - 1.4 9.2 7.9 0.096 12.9 0.6 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger TRP PF06011.12 EEQ32881.1 - 1.1e-18 67.2 19.2 1.1e-11 44.2 10.3 3.3 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EEQ32881.1 - 1.3e-18 67.7 0.2 2e-18 67.1 0.2 1.3 1 0 0 1 1 1 1 ML-like domain Lig_chan PF00060.26 EEQ32881.1 - 2.6 7.9 5.1 7.9 6.3 5.1 1.8 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4381 PF14316.6 EEQ32881.1 - 3.5 7.9 4.0 12 6.1 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Cys_Met_Meta_PP PF01053.20 EEQ32883.1 - 1.3e-63 214.8 0.0 5.7e-63 212.7 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EEQ32883.1 - 0.0019 17.2 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EEQ32883.1 - 0.0025 17.1 0.0 0.01 15.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II DUF2073 PF09846.9 EEQ32883.1 - 0.065 13.1 0.0 11 5.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) DegT_DnrJ_EryC1 PF01041.17 EEQ32883.1 - 0.17 11.2 0.0 0.47 9.7 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.25 EEQ32884.1 - 1.6e-20 73.6 0.0 2.1e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32884.1 - 4.1e-06 26.3 0.0 7.2e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ32884.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EEQ32884.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 EEQ32884.1 - 0.18 10.8 0.1 0.27 10.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ThiS PF02597.20 EEQ32885.1 - 0.00019 22.0 0.0 0.002 18.7 0.0 1.9 1 1 0 1 1 1 1 ThiS family GFA PF04828.14 EEQ32886.1 - 2.4e-19 69.5 1.5 2.4e-19 69.5 1.5 2.3 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF4467 PF14729.6 EEQ32886.1 - 0.095 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) Zn_clus PF00172.18 EEQ32887.1 - 1.2e-08 34.9 5.0 2.2e-08 34.1 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ32887.1 - 2.1e-08 33.5 0.1 4.6e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain ABC_tran PF00005.27 EEQ32888.1 - 9.6e-26 90.9 0.2 2.6e-25 89.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 EEQ32888.1 - 8.3e-23 80.9 26.6 3.6e-22 78.8 26.6 1.9 1 1 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 EEQ32888.1 - 2.6e-07 30.7 0.2 0.0099 15.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EEQ32888.1 - 1.6e-05 24.9 0.4 5.7e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EEQ32888.1 - 0.0001 21.8 0.3 0.00063 19.2 0.0 2.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EEQ32888.1 - 0.00028 21.3 0.2 0.0012 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EEQ32888.1 - 0.00079 19.0 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEQ32888.1 - 0.005 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 EEQ32888.1 - 0.0061 17.0 0.0 0.089 13.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EEQ32888.1 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 EEQ32888.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_29 PF13555.6 EEQ32888.1 - 0.0092 15.7 0.2 0.021 14.6 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ32888.1 - 0.0093 16.2 0.1 0.032 14.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EEQ32888.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_13 PF13166.6 EEQ32888.1 - 0.011 14.4 0.1 0.011 14.4 0.1 2.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EEQ32888.1 - 0.015 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ32888.1 - 0.016 15.8 0.2 0.047 14.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC2_membrane_3 PF12698.7 EEQ32888.1 - 0.032 13.4 12.4 0.057 12.5 12.4 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_28 PF13521.6 EEQ32888.1 - 0.034 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EEQ32888.1 - 0.061 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ32888.1 - 0.065 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 EEQ32888.1 - 0.14 12.7 0.9 0.29 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EEQ32888.1 - 0.17 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea tRNA-synt_2 PF00152.20 EEQ32889.1 - 6e-87 291.7 0.0 8.3e-87 291.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ32889.1 - 4.1e-06 26.7 0.1 8.1e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 EEQ32889.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EEQ32889.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) PEP_mutase PF13714.6 EEQ32891.1 - 4.8e-65 219.4 0.8 5.4e-65 219.2 0.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Aminotran_MocR PF12897.7 EEQ32891.1 - 0.024 13.5 0.1 0.11 11.3 0.1 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase ABC_tran PF00005.27 EEQ32892.1 - 1.3e-47 161.7 0.0 1.7e-29 103.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ32892.1 - 6.8e-36 124.3 37.5 7.4e-24 84.8 12.9 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EEQ32892.1 - 4.6e-11 42.6 0.0 0.014 14.9 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEQ32892.1 - 1.5e-05 25.6 0.7 0.0011 19.6 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ32892.1 - 2.3e-05 24.7 0.0 2.3 8.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EEQ32892.1 - 0.0004 20.5 0.3 0.096 12.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EEQ32892.1 - 0.0004 20.1 0.7 0.17 11.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EEQ32892.1 - 0.00042 20.7 0.7 0.5 10.7 0.1 3.3 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ32892.1 - 0.00078 19.4 0.1 0.96 9.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 EEQ32892.1 - 0.0013 17.8 0.0 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.6 EEQ32892.1 - 0.003 17.4 0.0 6.8 6.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EEQ32892.1 - 0.0053 16.9 1.9 1.1 9.3 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 EEQ32892.1 - 0.007 16.1 0.3 1.1 9.0 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein DUF2075 PF09848.9 EEQ32892.1 - 0.06 12.6 0.1 0.84 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EEQ32892.1 - 0.069 12.9 0.8 14 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EEQ32892.1 - 0.09 12.0 0.1 6.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 EEQ32892.1 - 0.11 11.9 0.5 27 4.1 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein MeaB PF03308.16 EEQ32892.1 - 0.14 11.1 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EEQ32892.1 - 0.16 12.0 0.9 28 4.8 0.5 3.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_15 PF13175.6 EEQ32892.1 - 0.23 11.1 0.1 15 5.2 0.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain PhoD PF09423.10 EEQ32893.1 - 1.4e-112 376.2 0.6 1.7e-112 375.9 0.6 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EEQ32893.1 - 2.3e-35 121.0 0.2 5.1e-35 119.9 0.2 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EEQ32893.1 - 1.7e-05 25.3 2.4 1.7e-05 25.3 2.4 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain LigD_N PF13298.6 EEQ32895.1 - 1.5e-15 57.4 0.0 2.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Sulf_transp PF04143.14 EEQ32896.1 - 1.1e-07 31.7 17.9 1.5e-06 28.0 1.0 3.3 3 0 0 3 3 3 3 Sulphur transport Peptidase_M28 PF04389.17 EEQ32897.1 - 9.2e-31 107.1 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Rhodanese PF00581.20 EEQ32900.1 - 1.2e-06 29.0 0.0 1.7e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HTH_17 PF12728.7 EEQ32900.1 - 0.0072 16.5 0.0 18 5.6 0.0 3.1 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_22 PF13309.6 EEQ32900.1 - 0.2 11.8 0.1 0.58 10.3 0.0 1.8 2 0 0 2 2 2 0 HTH domain MutS_V PF00488.21 EEQ32901.1 - 7.1e-67 225.1 0.1 1.3e-66 224.2 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EEQ32901.1 - 3.8e-42 144.7 0.0 9.4e-42 143.4 0.0 1.7 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EEQ32901.1 - 4.7e-33 113.8 0.1 2.2e-32 111.7 0.1 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EEQ32901.1 - 1.5e-15 57.3 1.3 3e-15 56.3 1.3 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EEQ32901.1 - 8.1e-13 48.8 0.0 2.6e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 EEQ32901.1 - 0.0045 17.5 0.1 0.0045 17.5 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 EEQ32901.1 - 0.019 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EEQ32901.1 - 0.057 13.2 0.2 0.14 11.9 0.2 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ32901.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T3SS_needle_E PF08988.10 EEQ32901.1 - 0.12 12.5 1.1 18 5.6 0.0 2.8 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle tRNA-synt_1b PF00579.25 EEQ32902.1 - 1.2e-62 211.9 0.0 1.1e-47 162.8 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EEQ32902.1 - 1.5e-43 147.4 0.0 3e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Raffinose_syn PF05691.12 EEQ32903.1 - 1e-50 172.4 7.2 1.7e-40 138.6 3.3 3.1 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Hen1_L PF12623.7 EEQ32903.1 - 0.073 12.1 0.2 4.2 6.3 0.1 2.2 2 0 0 2 2 2 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Aldedh PF00171.22 EEQ32904.1 - 4.8e-160 533.1 0.8 5.9e-160 532.8 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRN9 PF10680.9 EEQ32905.1 - 8.4e-21 74.0 0.2 8.4e-21 74.0 0.2 2.7 4 0 0 4 4 4 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.26 EEQ32905.1 - 0.39 11.3 1.6 0.51 10.9 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pescadillo_N PF06732.11 EEQ32906.1 - 1.2e-124 415.3 0.1 1.2e-124 415.3 0.1 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EEQ32906.1 - 0.0051 17.2 0.0 0.019 15.3 0.0 2.1 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EEQ32906.1 - 0.021 15.2 0.0 0.92 9.9 0.0 3.1 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.13 EEQ32907.1 - 4.6e-119 397.9 25.9 5.3e-119 397.7 25.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Zip PF02535.22 EEQ32907.1 - 0.41 9.8 3.1 0.24 10.6 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Acetyltransf_1 PF00583.25 EEQ32908.1 - 2e-11 44.2 0.0 2.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ32908.1 - 2e-08 34.2 0.0 3.8e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ32908.1 - 2.1e-08 34.4 0.0 3.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ32908.1 - 0.00012 22.0 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EEQ32908.1 - 0.028 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EEQ32908.1 - 0.035 14.8 0.0 0.048 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.15 EEQ32909.1 - 7.8e-13 48.3 0.0 1.1e-08 35.0 0.0 2.4 2 0 0 2 2 2 2 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEQ32909.1 - 0.00042 21.0 0.0 0.00073 20.2 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like HIG_1_N PF04588.13 EEQ32910.1 - 7.6e-30 102.9 0.6 1.1e-29 102.4 0.6 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Ureide_permease PF07168.11 EEQ32910.1 - 0.17 10.6 0.2 0.24 10.1 0.2 1.1 1 0 0 1 1 1 0 Ureide permease PALP PF00291.25 EEQ32911.1 - 8e-68 229.0 2.3 2.1e-67 227.6 2.3 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EEQ32911.1 - 8.5e-44 147.2 0.0 2.3e-21 75.3 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.18 EEQ32912.1 - 4.2e-21 74.9 9.8 8e-21 74.0 9.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 GTP_EFTU PF00009.27 EEQ32913.1 - 1.4e-58 197.7 0.4 2.5e-58 196.9 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EEQ32913.1 - 2.5e-33 114.4 0.0 5.4e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EEQ32913.1 - 3.9e-32 110.2 0.0 7.8e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EEQ32913.1 - 2.1e-24 85.3 0.0 6.9e-24 83.7 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEQ32913.1 - 5.8e-11 42.6 0.0 2.2e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EEQ32913.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain ATP_bind_1 PF03029.17 EEQ32913.1 - 0.016 15.0 0.1 0.057 13.2 0.1 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EEQ32913.1 - 0.15 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Abhydrolase_6 PF12697.7 EEQ32914.1 - 1.2e-11 45.6 0.1 1.9e-11 45.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ32914.1 - 4e-08 32.8 0.0 7.3e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ32914.1 - 8.8e-07 28.8 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EEQ32914.1 - 0.00022 21.2 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 EEQ32914.1 - 0.0024 16.9 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 EEQ32914.1 - 0.12 11.8 0.0 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family TLD PF07534.16 EEQ32916.1 - 2.8e-18 66.5 0.0 6.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 EEQ32916.1 - 0.0013 19.7 1.8 0.014 16.4 1.8 2.5 1 1 0 1 1 1 1 Domain of unknown function NMT_C PF02799.15 EEQ32917.1 - 2.4e-88 295.1 0.1 3.5e-88 294.6 0.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EEQ32917.1 - 1.6e-71 239.4 0.0 2.8e-71 238.5 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EEQ32917.1 - 0.00015 21.8 0.0 0.00046 20.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mur_ligase_M PF08245.12 EEQ32918.1 - 2.9e-06 27.4 0.3 6.3e-05 23.0 0.3 2.9 1 1 0 1 1 1 1 Mur ligase middle domain Syja_N PF02383.18 EEQ32919.1 - 1.9e-89 300.2 0.0 2.4e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain FUN14 PF04930.15 EEQ32919.1 - 0.085 13.3 0.1 1 9.8 0.0 2.7 3 0 0 3 3 3 0 FUN14 family adh_short PF00106.25 EEQ32920.1 - 4.7e-26 91.5 0.0 1.4e-25 89.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ32920.1 - 3e-22 79.3 0.0 1.3e-21 77.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ32920.1 - 4.1e-05 23.6 1.4 0.00018 21.5 0.2 2.3 2 1 0 2 2 2 1 KR domain zf-CCCH PF00642.24 EEQ32921.1 - 1.9e-18 65.9 30.2 2.2e-06 27.4 0.7 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ32921.1 - 1.2e-11 44.2 34.0 0.00058 19.8 2.5 5.2 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 EEQ32921.1 - 3e-09 37.5 28.6 0.00023 21.8 1.1 5.5 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 EEQ32921.1 - 4.1e-05 23.3 0.8 4.1e-05 23.3 0.8 4.9 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EEQ32921.1 - 0.25 11.5 12.5 18 5.6 5.1 3.5 2 1 1 3 3 3 0 Zinc-finger containing family zf-C3H1 PF10650.9 EEQ32921.1 - 2.9 7.7 10.3 1.2 9.0 0.4 3.5 3 0 0 3 3 3 0 Putative zinc-finger domain AWS PF17907.1 EEQ32921.1 - 7.7 6.7 16.4 13 5.9 0.2 4.6 5 0 0 5 5 5 0 AWS domain Glyco_hydro_18 PF00704.28 EEQ32922.1 - 8.2e-53 180.2 0.0 1.1e-52 179.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 EEQ32923.1 - 4.9e-14 52.3 0.0 2.5e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32923.1 - 2.7e-05 23.6 0.0 5.9e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ32923.1 - 0.0034 16.2 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEQ32923.1 - 0.0061 16.5 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ32923.1 - 0.027 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3712 PF12505.8 EEQ32924.1 - 5.1e-34 117.2 3.9 1.3e-33 115.9 1.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF3139 PF11337.8 EEQ32924.1 - 0.0069 17.0 0.0 0.019 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3139) Wzy_C PF04932.15 EEQ32924.1 - 0.094 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase DUF4307 PF14155.6 EEQ32924.1 - 0.15 11.9 0.3 0.29 11.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Sel1 PF08238.12 EEQ32925.1 - 3.3e-11 43.5 11.0 0.00029 21.4 2.6 4.1 4 0 0 4 4 4 3 Sel1 repeat Glyco_hydro_18 PF00704.28 EEQ32926.1 - 2.1e-24 86.9 0.4 3.9e-23 82.7 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4849 PF16141.5 EEQ32926.1 - 0.095 11.9 0.5 0.28 10.4 0.1 1.9 2 1 0 2 2 2 0 Putative glycoside hydrolase Family 18, chitinase_18 Methyltransf_11 PF08241.12 EEQ32927.1 - 4.3e-29 101.0 0.3 4e-14 53.0 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ32927.1 - 2.3e-28 98.8 0.2 7.2e-15 55.5 0.0 3.4 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ32927.1 - 2.3e-17 63.2 0.1 2.7e-09 37.0 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ32927.1 - 2e-16 60.3 0.0 8.1e-11 42.0 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ32927.1 - 4e-14 53.1 0.0 2.5e-08 34.5 0.0 3.0 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ32927.1 - 1.1e-09 38.0 0.0 4e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MetW PF07021.12 EEQ32927.1 - 1.6e-07 31.2 0.0 0.015 14.9 0.0 2.5 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW CMAS PF02353.20 EEQ32927.1 - 3e-07 30.0 0.0 7.7e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 EEQ32927.1 - 1.8e-05 24.5 0.0 4.4e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 EEQ32927.1 - 0.00038 20.3 0.0 0.00088 19.1 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 EEQ32927.1 - 0.00083 18.9 0.1 0.37 10.2 0.0 2.6 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain TehB PF03848.14 EEQ32927.1 - 0.00085 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 EEQ32927.1 - 0.0011 18.6 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) UPF0146 PF03686.13 EEQ32927.1 - 0.0016 18.3 0.0 0.0061 16.4 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0146) DOT1 PF08123.13 EEQ32927.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_9 PF08003.11 EEQ32927.1 - 0.049 12.6 0.0 5.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) FtsJ PF01728.19 EEQ32927.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 EEQ32927.1 - 0.067 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EEQ32927.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 3HCDH_N PF02737.18 EEQ32927.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pox_MCEL PF03291.16 EEQ32927.1 - 0.12 11.4 0.0 0.59 9.2 0.0 2.0 2 1 1 3 3 3 0 mRNA capping enzyme Methyltransf_33 PF10017.9 EEQ32927.1 - 0.2 10.8 0.0 0.44 9.7 0.0 1.6 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Myc_target_1 PF15179.6 EEQ32928.1 - 2 8.3 4.6 11 5.8 4.6 2.0 1 1 0 1 1 1 0 Myc target protein 1 Shisa PF13908.6 EEQ32928.1 - 6.5 7.0 13.5 0.039 14.2 3.0 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator F-box PF00646.33 EEQ32929.1 - 0.0013 18.6 5.1 0.0019 18.0 0.0 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EEQ32929.1 - 0.0051 16.7 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EEQ32929.1 - 0.093 12.6 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 F-box Yip1 PF04893.17 EEQ32930.1 - 0.00016 21.5 19.4 0.004 16.9 9.3 2.1 2 0 0 2 2 2 2 Yip1 domain 7tm_7 PF08395.12 EEQ32930.1 - 0.075 12.2 21.4 0.19 10.9 21.4 1.6 1 1 0 1 1 1 0 7tm Chemosensory receptor DHHC PF01529.20 EEQ32930.1 - 6.2 6.9 15.1 2 8.5 0.1 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase tRNA-synt_1g PF09334.11 EEQ32931.1 - 0.024 13.4 0.0 1.3 7.7 0.0 2.1 1 1 1 2 2 2 0 tRNA synthetases class I (M) DUF1776 PF08643.10 EEQ32932.1 - 4.3e-90 302.1 0.0 5.2e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WLM PF08325.10 EEQ32933.1 - 1.3e-65 221.1 0.1 2.3e-65 220.3 0.1 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EEQ32933.1 - 0.00093 18.5 3.4 0.00093 18.5 3.4 3.2 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 EEQ32933.1 - 0.0036 17.4 2.1 0.0084 16.2 2.1 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 EEQ32933.1 - 0.014 15.2 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 SprT-like family Peptidase_M54 PF07998.11 EEQ32933.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 CDV3 PF15359.6 EEQ32933.1 - 0.069 13.6 0.7 0.16 12.4 0.7 1.6 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Trp_DMAT PF11991.8 EEQ32934.1 - 1.5e-107 360.2 0.0 1.8e-107 360.0 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_3 PF01494.19 EEQ32935.1 - 1.7e-13 50.6 1.0 4.6e-09 36.0 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EEQ32935.1 - 1.4e-07 31.0 1.8 0.0011 18.2 0.3 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEQ32935.1 - 1.1e-06 28.0 1.0 2.3e-06 27.0 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EEQ32935.1 - 2.7e-06 26.4 0.2 0.00035 19.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 EEQ32935.1 - 8.2e-06 25.6 2.9 0.005 16.5 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ32935.1 - 0.00076 19.7 0.5 0.075 13.3 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EEQ32935.1 - 0.0061 15.8 0.1 0.2 10.9 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EEQ32935.1 - 0.0088 15.4 0.2 0.014 14.8 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EEQ32935.1 - 0.015 14.6 0.2 0.031 13.6 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EEQ32935.1 - 0.02 14.0 1.9 0.036 13.1 1.9 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EEQ32935.1 - 0.045 14.3 0.4 5.1 7.7 0.3 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 EEQ32937.1 - 1.2e-75 254.7 0.0 2.2e-75 253.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EEQ32937.1 - 3.9e-41 141.2 0.0 3e-17 62.4 0.0 6.5 5 1 1 6 6 6 5 Condensation domain PP-binding PF00550.25 EEQ32937.1 - 1.3e-28 99.1 0.5 1.8e-13 50.6 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ32937.1 - 0.007 17.3 0.1 0.04 14.9 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribonuclease PF00545.20 EEQ32938.1 - 1.9e-06 28.5 0.1 2.6e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 ribonuclease DIM PF08194.12 EEQ32938.1 - 0.89 9.8 0.1 0.89 9.8 0.1 2.6 3 0 0 3 3 3 0 DIM protein WD40 PF00400.32 EEQ32939.1 - 1.7e-44 148.9 32.2 2.3e-05 25.0 0.1 11.6 11 1 0 11 11 11 9 WD domain, G-beta repeat Utp12 PF04003.12 EEQ32939.1 - 1.1e-22 80.3 0.0 2.4e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EEQ32939.1 - 2.2e-19 69.5 5.7 0.0014 18.9 0.0 9.6 4 2 5 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ32939.1 - 2.9e-09 36.4 0.8 0.062 12.3 0.3 4.9 4 1 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEQ32939.1 - 1.2e-05 24.1 0.3 0.33 9.6 0.0 4.6 5 0 0 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EEQ32939.1 - 2.2e-05 23.9 0.0 0.69 9.2 0.0 3.8 4 0 0 4 4 4 2 WD40-like domain Frtz PF11768.8 EEQ32939.1 - 0.0086 14.4 0.0 0.22 9.8 0.0 2.4 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Utp13 PF08625.11 EEQ32939.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain P34-Arc PF04045.14 EEQ32940.1 - 1.2e-104 349.2 0.0 1.5e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF2158 PF09926.9 EEQ32940.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) PP2C PF00481.21 EEQ32942.1 - 7.3e-05 22.5 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EEQ32942.1 - 0.0034 17.3 0.1 0.014 15.3 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Fcf1 PF04900.12 EEQ32943.1 - 2.7e-19 69.4 0.2 4.9e-10 39.7 0.0 2.8 2 1 0 2 2 2 2 Fcf1 Cmc1 PF08583.10 EEQ32944.1 - 9.4e-19 67.2 6.6 1.1e-18 67.0 6.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like UxaE PF16257.5 EEQ32944.1 - 0.12 11.1 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 tagaturonate epimerase DUF1296 PF06972.11 EEQ32944.1 - 0.49 10.6 3.4 11 6.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) WD40 PF00400.32 EEQ32945.1 - 5.4e-15 55.5 16.0 0.00091 20.0 0.3 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EEQ32945.1 - 0.00088 18.0 5.0 0.02 13.6 1.2 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EEQ32945.1 - 0.0062 16.8 1.7 0.56 10.5 0.2 3.8 4 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EEQ32945.1 - 0.22 10.2 0.3 6.7 5.3 0.1 2.9 2 1 1 3 3 3 0 Nup133 N terminal like Myc_N PF01056.18 EEQ32945.1 - 0.57 10.0 9.9 0.23 11.3 6.6 1.9 2 0 0 2 2 2 0 Myc amino-terminal region DUF4398 PF14346.6 EEQ32945.1 - 1.4 9.6 7.6 0.27 11.9 3.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Astro_capsid_p PF12226.8 EEQ32945.1 - 7.4 5.6 23.9 0.027 13.6 14.0 1.9 2 0 0 2 2 2 0 Turkey astrovirus capsid protein RNA_polI_A34 PF08208.11 EEQ32945.1 - 8 6.5 13.6 7.4 6.6 0.9 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 APH PF01636.23 EEQ32946.1 - 2.6e-12 47.2 0.0 1.1e-11 45.1 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF5053 PF16476.5 EEQ32946.1 - 0.0017 18.0 0.2 0.0098 15.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5053) Fructosamin_kin PF03881.14 EEQ32946.1 - 0.015 14.5 0.1 0.04 13.1 0.0 1.6 2 0 0 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.20 EEQ32946.1 - 0.035 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Hamartin PF04388.12 EEQ32947.1 - 0.13 10.9 10.8 0.15 10.7 10.8 1.0 1 0 0 1 1 1 0 Hamartin protein FAM220 PF15487.6 EEQ32947.1 - 0.92 9.1 7.0 1.6 8.3 6.9 1.4 1 1 0 1 1 1 0 FAM220 family RRN3 PF05327.11 EEQ32949.1 - 1.6e-146 489.1 0.0 2.9e-142 475.1 0.0 2.9 2 1 1 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_3 PF07859.13 EEQ32950.1 - 2.9e-40 138.4 0.1 8.1e-31 107.5 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 EEQ32950.1 - 7.5e-11 41.6 0.0 1.5e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF3439 PF11921.8 EEQ32950.1 - 0.025 14.5 2.4 0.24 11.4 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF2974 PF11187.8 EEQ32950.1 - 0.026 14.1 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Mucin PF01456.17 EEQ32950.1 - 0.034 14.1 4.6 0.053 13.5 4.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Esterase PF00756.20 EEQ32950.1 - 0.039 13.6 0.3 0.075 12.7 0.3 1.6 1 1 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 EEQ32950.1 - 0.045 12.7 0.1 0.098 11.5 0.1 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.12 EEQ32950.1 - 0.12 11.1 0.1 2.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) tRNA-synt_2 PF00152.20 EEQ32951.1 - 1e-71 241.6 0.0 1.5e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EEQ32951.1 - 4.6e-19 68.6 0.0 6.5e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EEQ32951.1 - 0.00022 21.1 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EEQ32951.1 - 0.00083 18.9 0.1 0.9 9.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ank_2 PF12796.7 EEQ32953.1 - 1.4e-27 96.1 5.1 8.6e-10 39.1 0.2 4.9 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ32953.1 - 7.8e-25 86.9 5.2 1.1e-05 25.9 0.0 7.3 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ32953.1 - 2.7e-16 58.0 3.8 0.0087 16.5 0.0 8.0 7 1 1 8 8 8 4 Ankyrin repeat Ank PF00023.30 EEQ32953.1 - 2.7e-10 40.2 15.5 0.02 15.3 0.1 6.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EEQ32953.1 - 2.1e-07 31.1 7.3 1.5 9.3 0.1 7.4 3 1 6 9 9 9 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 EEQ32953.1 - 0.0029 17.5 0.0 1.9 8.5 0.0 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Shigella_OspC PF06128.11 EEQ32953.1 - 0.15 11.8 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Shigella flexneri OspC protein HLH PF00010.26 EEQ32954.1 - 2.4e-14 53.0 0.2 2.4e-14 53.0 0.2 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF5583 PF17821.1 EEQ32955.1 - 0.054 13.4 0.2 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5583) Septin PF00735.18 EEQ32957.1 - 1e-07 31.6 0.1 3.4e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Septin DDE_Tnp_1 PF01609.21 EEQ32957.1 - 0.18 11.4 0.0 0.69 9.5 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain HSP90 PF00183.18 EEQ32958.1 - 1.3e-219 730.4 31.5 1.6e-219 730.1 31.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EEQ32958.1 - 6.2e-15 55.7 0.1 1.1e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EEQ32958.1 - 1e-08 35.1 0.1 1e-08 35.1 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ProQ PF04352.13 EEQ32958.1 - 0.062 13.2 1.3 0.7 9.8 0.3 2.5 2 0 0 2 2 2 0 ProQ/FINO family LOH1CR12 PF10158.9 EEQ32958.1 - 0.071 13.1 0.2 0.26 11.3 0.2 2.0 1 0 0 1 1 1 0 Tumour suppressor protein NTF2 PF02136.20 EEQ32959.1 - 1.7e-23 83.5 0.4 2.8e-23 82.8 0.4 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EEQ32959.1 - 2e-08 33.9 0.1 3.3e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EEQ32959.1 - 0.023 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif BssS PF13991.6 EEQ32960.1 - 0.058 13.5 0.1 0.19 11.8 0.0 1.9 2 1 0 2 2 2 0 BssS protein family PknG_rubred PF16919.5 EEQ32960.1 - 0.1 12.7 2.6 3.6 7.7 0.5 2.1 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain TPR_17 PF13431.6 EEQ32961.1 - 9.6e-05 22.5 0.1 0.46 11.0 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ32961.1 - 0.0036 17.0 6.1 0.065 12.9 0.0 4.2 4 0 0 4 4 4 1 TPR repeat TPR_16 PF13432.6 EEQ32961.1 - 0.0067 17.0 1.6 14 6.4 0.1 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ32961.1 - 0.026 15.3 3.7 7.2 7.7 0.3 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ32961.1 - 0.05 13.7 0.1 2.1 8.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ32961.1 - 0.094 12.6 0.3 4.9 7.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Nnf1 PF03980.14 EEQ32962.1 - 3.1e-31 108.0 0.5 6.9e-31 106.9 0.5 1.6 1 0 0 1 1 1 1 Nnf1 HAUS4 PF14735.6 EEQ32962.1 - 0.027 14.2 0.4 0.047 13.4 0.4 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Cnn_1N PF07989.11 EEQ32962.1 - 0.031 14.4 1.3 0.058 13.5 0.6 1.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Baculo_F PF12259.8 EEQ32962.1 - 0.16 10.5 0.0 0.17 10.4 0.0 1.0 1 0 0 1 1 1 0 Baculovirus F protein Mod_r PF07200.13 EEQ32962.1 - 0.17 12.0 5.2 0.12 12.4 3.1 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.21 EEQ32962.1 - 1.5 8.9 5.7 0.83 9.8 2.6 2.2 3 0 0 3 3 3 0 bZIP transcription factor Pkinase PF00069.25 EEQ32963.1 - 4.3e-67 226.3 0.0 7.5e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32963.1 - 2.1e-32 112.5 0.3 3.3e-32 111.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ32963.1 - 0.00082 18.4 0.1 0.00082 18.4 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EEQ32963.1 - 0.016 15.1 3.9 0.048 13.6 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EEQ32963.1 - 0.019 14.3 0.6 0.019 14.3 0.6 2.1 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ32963.1 - 0.028 13.8 0.0 0.028 13.8 0.0 2.1 2 1 0 2 2 2 0 Kinase-like Spt20 PF12090.8 EEQ32963.1 - 3.2 7.3 11.5 5.9 6.4 11.5 1.4 1 0 0 1 1 1 0 Spt20 family SIR2 PF02146.17 EEQ32964.1 - 7.6e-36 123.7 0.0 1.2e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family AATase PF07247.12 EEQ32965.1 - 8.4e-17 60.9 0.0 2.6e-16 59.3 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 EEQ32965.1 - 0.0034 16.1 0.0 0.17 10.5 0.0 2.1 2 0 0 2 2 2 2 Condensation domain Cation_efflux PF01545.21 EEQ32966.1 - 1.5e-54 184.8 5.6 1.9e-54 184.4 5.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EEQ32966.1 - 0.00025 21.1 0.0 0.00069 19.7 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Herpes_TK PF00693.18 EEQ32966.1 - 0.028 13.7 1.0 0.048 12.9 1.0 1.3 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus SelP_N PF04592.14 EEQ32966.1 - 6.2 6.1 10.7 0.15 11.4 3.5 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region FGGY_C PF02782.16 EEQ32967.1 - 1.3e-30 106.7 0.0 2e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EEQ32967.1 - 1.5e-14 54.2 0.0 8.4e-07 28.8 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.12 EEQ32968.1 - 1.4e-38 132.3 0.4 1.4e-38 132.3 0.4 2.7 3 0 0 3 3 3 1 Exportin 1-like protein SEO_N PF14576.6 EEQ32968.1 - 0.047 12.9 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 Sieve element occlusion N-terminus HEAT PF02985.22 EEQ32968.1 - 0.074 13.3 0.0 1.2e+02 3.4 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat Esterase PF00756.20 EEQ32969.1 - 1.2e-52 179.1 0.0 1.5e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EEQ32969.1 - 0.00084 18.9 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 EEQ32969.1 - 0.00094 18.7 0.0 0.017 14.6 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EEQ32969.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 EEQ32969.1 - 0.0092 15.5 0.1 0.031 13.8 0.0 1.8 2 1 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 EEQ32969.1 - 0.016 14.1 0.0 0.034 13.0 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EEQ32969.1 - 0.038 14.6 0.0 0.042 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EEQ32969.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 EEQ32969.1 - 0.081 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_C2 PF00648.21 EEQ32969.1 - 0.2 10.6 0.7 0.3 10.1 0.7 1.1 1 0 0 1 1 1 0 Calpain family cysteine protease Peptidase_C50 PF03568.17 EEQ32970.1 - 4e-151 503.6 0.0 2.7e-150 500.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase family C50 TPR_2 PF07719.17 EEQ32970.1 - 0.0028 17.6 1.6 5.6 7.3 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat CHAT PF12770.7 EEQ32970.1 - 0.048 13.1 0.0 0.69 9.3 0.0 2.4 2 0 0 2 2 2 0 CHAT domain TPR_10 PF13374.6 EEQ32970.1 - 0.69 9.9 2.1 24 4.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ32970.1 - 6.1 7.2 8.8 64 3.9 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5321 PF17254.2 EEQ32971.1 - 3.2e-48 163.2 0.8 3.9e-48 162.9 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) RHD3 PF05879.12 EEQ32971.1 - 0.015 13.5 0.0 0.018 13.2 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Fungal_trans PF04082.18 EEQ32975.1 - 1.9e-19 69.7 1.3 2.7e-19 69.2 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ32975.1 - 6.4e-09 35.8 11.9 1.3e-08 34.8 11.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 EEQ32976.1 - 7.1e-62 209.6 0.0 9.1e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1360 PF07098.11 EEQ32976.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Terpene_synth_C PF03936.16 EEQ32978.1 - 7.9e-09 35.2 0.1 1.2e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.22 EEQ32979.1 - 1.1e-30 106.8 0.1 2.5e-16 59.5 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 MFS_1 PF07690.16 EEQ32982.1 - 1.9e-38 132.3 44.5 2.7e-35 121.9 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ32982.1 - 4.3e-08 32.5 6.2 4.3e-08 32.5 6.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter ExoD PF06055.12 EEQ32982.1 - 0.0016 17.8 1.0 0.0016 17.8 1.0 2.6 2 1 1 3 3 3 1 Exopolysaccharide synthesis, ExoD TRI12 PF06609.13 EEQ32982.1 - 0.0025 16.3 0.9 0.0025 16.3 0.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EEQ32982.1 - 0.18 10.6 17.4 0.0039 16.1 2.8 2.8 1 1 1 2 2 2 0 MFS_1 like family TFR_dimer PF04253.15 EEQ32983.1 - 1.3e-29 102.7 0.0 2.2e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EEQ32983.1 - 3.7e-21 75.7 0.0 7.4e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EEQ32983.1 - 3.1e-09 36.7 0.1 8e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 EEQ32983.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Seadorna_Vp10 PF07322.11 EEQ32983.1 - 0.064 12.7 0.6 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus Vp10 MKT1_C PF12246.8 EEQ32983.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Peptidase_M20 PF01546.28 EEQ32983.1 - 0.13 11.9 0.1 1.4 8.5 0.1 2.2 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 zf-C2H2_4 PF13894.6 EEQ32984.1 - 0.0024 18.6 4.2 0.33 11.9 0.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EEQ32984.1 - 3.7 8.2 5.0 35 5.1 0.3 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type IHABP4_N PF16174.5 EEQ32984.1 - 4.8 7.8 11.1 1.2 9.7 1.6 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal CMD PF02627.20 EEQ32986.1 - 2.4e-07 30.7 0.1 7.8e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family CBFD_NFYB_HMF PF00808.23 EEQ32987.1 - 2.1e-23 82.3 1.0 4e-23 81.5 1.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ32987.1 - 0.00059 20.2 0.1 0.0013 19.1 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EEQ32987.1 - 0.0071 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 EEQ32987.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 EEQ32987.1 - 0.026 14.6 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EEQ32987.1 - 0.24 11.9 0.0 0.54 10.8 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 EEQ32988.1 - 1.1e-24 86.4 6.5 1.2e-24 86.2 6.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF1351 PF07083.11 EEQ32988.1 - 0.0074 16.1 1.5 1.3 8.8 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1351) ZnuA PF01297.17 EEQ32988.1 - 0.014 14.8 1.0 0.79 9.1 0.2 2.0 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Prefoldin PF02996.17 EEQ32988.1 - 0.017 15.0 4.6 0.039 13.9 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit DASH_Dad3 PF08656.10 EEQ32988.1 - 0.029 14.5 1.0 0.13 12.3 0.2 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 CLZ PF16526.5 EEQ32988.1 - 0.04 14.3 3.2 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2205 PF10224.9 EEQ32988.1 - 0.046 13.7 5.9 0.054 13.5 0.9 2.1 2 0 0 2 2 2 0 Short coiled-coil protein p25-alpha PF05517.12 EEQ32988.1 - 0.06 13.5 1.5 1 9.5 0.1 2.0 2 0 0 2 2 2 0 p25-alpha ZapB PF06005.12 EEQ32988.1 - 0.14 12.7 4.7 1.8 9.1 1.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 EEQ32988.1 - 0.2 11.9 5.1 1.2 9.4 0.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TnpV PF14198.6 EEQ32988.1 - 0.49 10.4 5.0 1 9.4 0.5 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Fungal_trans PF04082.18 EEQ32989.1 - 4.6e-14 52.1 0.0 2.3e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ32989.1 - 1.9e-09 37.5 11.0 3.2e-09 36.8 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TF_Zn_Ribbon PF08271.12 EEQ32989.1 - 7.4 6.2 8.1 0.16 11.5 0.2 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Aminotran_1_2 PF00155.21 EEQ32990.1 - 8.2e-18 64.7 0.0 1.4e-17 63.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EEQ32990.1 - 0.0077 15.1 0.0 0.037 12.8 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Pkinase PF00069.25 EEQ32991.1 - 8.6e-42 143.3 0.0 1.3e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32991.1 - 5.8e-31 107.7 0.0 1e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EEQ32993.1 - 2.5e-61 207.4 0.0 3.9e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ32993.1 - 4.2e-28 98.4 0.0 9.1e-28 97.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ32993.1 - 1.2e-05 24.8 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ32993.1 - 0.0021 17.4 0.0 0.005 16.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEQ32993.1 - 0.0023 16.8 0.0 0.0044 15.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EEQ32993.1 - 0.041 13.4 0.1 0.31 10.5 0.0 2.4 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL TetR_C_27 PF17935.1 EEQ32993.1 - 0.059 13.4 0.0 0.53 10.4 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain UQ_con PF00179.26 EEQ32994.1 - 1.1e-25 89.9 0.0 1.4e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ32994.1 - 0.00014 21.6 0.0 0.00025 20.7 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EEQ32994.1 - 0.03 14.6 0.1 0.037 14.3 0.1 1.3 1 0 0 1 1 1 0 RWD domain Complex1_49kDa PF00346.19 EEQ32995.1 - 1.7e-123 411.0 0.0 2.4e-123 410.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EEQ32995.1 - 0.01 14.8 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 EEQ32996.1 - 2e-25 89.3 0.0 3.8e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EEQ32996.1 - 1.5e-19 69.2 0.0 2e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.21 EEQ32997.1 - 4.2e-63 213.0 0.0 8.4e-63 212.0 0.0 1.4 1 1 1 2 2 2 1 ThiF family E2_bind PF08825.10 EEQ32997.1 - 1e-29 102.5 0.4 1.8e-29 101.7 0.4 1.4 1 0 0 1 1 1 1 E2 binding domain E1_UFD PF09358.10 EEQ32997.1 - 0.0095 16.6 0.0 0.025 15.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain Ecm33 PF12454.8 EEQ32997.1 - 0.051 13.7 1.2 0.11 12.7 1.2 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein UBA_e1_thiolCys PF10585.9 EEQ32997.1 - 0.2 11.6 3.7 2.7 7.8 0.1 2.5 2 1 0 2 2 2 0 Ubiquitin-activating enzyme active site Telomere_reg-2 PF10193.9 EEQ32998.1 - 9.2e-28 96.9 0.0 2.2e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Fungal_trans PF04082.18 EEQ32999.1 - 1.7e-23 83.0 0.1 2.8e-23 82.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ32999.1 - 6.5e-09 35.8 11.8 1.3e-08 34.8 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_2 PF00890.24 EEQ33000.1 - 1.6e-07 30.8 0.0 0.0089 15.1 0.0 2.2 1 1 0 2 2 2 2 FAD binding domain zf-C2H2 PF00096.26 EEQ33005.1 - 5.2e-10 39.2 11.4 1.3e-05 25.3 4.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ33005.1 - 5.3e-10 39.3 14.6 2.3e-05 24.6 0.4 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ33005.1 - 4.1e-07 30.3 10.3 0.00057 20.5 2.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EEQ33005.1 - 6.5e-06 26.4 3.6 1.7e-05 25.0 1.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ33005.1 - 7.4e-05 22.6 8.7 0.00013 21.9 2.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ33005.1 - 0.00014 22.1 5.9 0.00064 19.9 2.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EEQ33005.1 - 0.024 14.5 4.3 2.9 7.9 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TFIIA PF03153.13 EEQ33005.1 - 0.048 13.7 13.1 0.057 13.4 13.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Actin_micro PF17003.5 EEQ33005.1 - 0.22 10.6 0.2 0.31 10.2 0.2 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_11 PF16622.5 EEQ33005.1 - 0.74 9.6 7.3 7 6.5 0.8 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EEQ33005.1 - 0.82 9.7 4.5 0.38 10.8 0.6 2.1 2 0 0 2 2 2 0 BED zinc finger V-SNARE_C PF12352.8 EEQ33006.1 - 1.4 9.3 6.9 0.1 12.9 0.8 2.2 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Sec1 PF00995.23 EEQ33007.1 - 1.7e-120 403.9 0.0 2e-120 403.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SF3b1 PF08920.10 EEQ33008.1 - 2.4e-33 115.1 11.1 1.3e-31 109.5 11.1 3.0 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EEQ33008.1 - 8.6e-11 42.1 2.9 0.011 16.2 0.0 6.7 7 1 1 8 8 7 2 HEAT-like repeat HEAT_2 PF13646.6 EEQ33008.1 - 1.6e-10 41.2 8.5 0.21 12.0 0.1 7.9 6 2 3 9 9 9 3 HEAT repeats HEAT PF02985.22 EEQ33008.1 - 1.9e-08 33.9 9.3 0.71 10.3 0.2 8.8 9 0 0 9 9 8 2 HEAT repeat Cnd1 PF12717.7 EEQ33008.1 - 2.2e-05 24.6 1.4 5 7.1 0.0 6.1 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EEQ33008.1 - 4.4e-05 24.0 0.2 2.4 8.8 0.0 5.4 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EEQ33008.1 - 0.0002 21.3 0.9 0.063 13.2 0.0 4.7 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 EEQ33008.1 - 0.00026 20.7 0.2 1.2 8.8 0.0 4.0 5 0 0 5 5 5 2 NUC173 domain UNC45-central PF11701.8 EEQ33008.1 - 0.00098 19.1 0.0 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central UME PF08064.13 EEQ33008.1 - 0.005 16.7 0.5 8.5 6.4 0.0 4.8 7 0 0 7 7 7 1 UME (NUC010) domain CLASP_N PF12348.8 EEQ33008.1 - 0.0053 16.4 0.1 0.95 9.0 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal TAF6_C PF07571.13 EEQ33008.1 - 0.023 15.0 0.0 0.99 9.8 0.0 3.4 3 1 0 3 3 2 0 TAF6 C-terminal HEAT repeat domain DRIM PF07539.12 EEQ33008.1 - 0.092 11.0 0.2 8.7 4.5 0.0 3.6 2 1 2 4 4 4 0 Down-regulated in metastasis Ecm29 PF13001.7 EEQ33008.1 - 0.18 10.4 0.0 1.6 7.3 0.0 2.3 2 1 1 3 3 3 0 Proteasome stabiliser DUF3455 PF11937.8 EEQ33009.1 - 9.1e-32 110.6 0.0 1.2e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Methyltransf_11 PF08241.12 EEQ33010.1 - 0.0022 18.6 0.0 0.0044 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EEQ33010.1 - 0.031 13.5 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_25 PF13649.6 EEQ33010.1 - 0.07 13.8 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SAP PF02037.27 EEQ33011.1 - 3.9e-12 45.6 0.5 7.7e-12 44.7 0.1 1.8 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 EEQ33011.1 - 2.4e-06 27.3 0.5 2.4e-06 27.3 0.5 2.0 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain Filo_glycop PF01611.16 EEQ33011.1 - 0.064 12.2 2.8 0.083 11.8 2.8 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein CCT_2 PF09425.10 EEQ33011.1 - 0.26 11.2 7.9 0.81 9.6 1.3 2.8 2 0 0 2 2 2 0 Divergent CCT motif SSrecog PF03531.14 EEQ33012.1 - 1.1e-30 105.3 0.4 1.7e-29 101.5 0.0 3.1 4 0 0 4 4 4 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 EEQ33012.1 - 3.5e-30 104.3 0.4 1e-28 99.6 0.1 2.8 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 EEQ33012.1 - 1.5e-25 89.4 0.1 6.8e-25 87.3 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Rax2 PF12768.7 EEQ33013.1 - 3.8e-68 229.2 0.0 1.4e-67 227.3 0.0 2.1 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Reg_prop PF07494.11 EEQ33013.1 - 1 9.8 6.7 19 5.9 0.0 5.8 7 0 0 7 7 7 0 Two component regulator propeller Zn_clus PF00172.18 EEQ33014.1 - 7.7e-09 35.5 11.1 1.5e-08 34.6 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EEQ33014.1 - 6e-08 31.9 0.0 8.6e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.6 EEQ33015.1 - 3.5e-11 42.9 0.3 2.2e-07 30.5 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EEQ33015.1 - 7.1e-10 37.9 1.3 6.4e-09 34.8 0.5 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EEQ33015.1 - 5e-09 35.7 0.6 0.00017 20.8 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EEQ33015.1 - 8.4e-09 35.1 0.0 4.2e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ33015.1 - 3e-08 33.8 0.0 6.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ33015.1 - 3.5e-08 33.4 0.0 0.00093 18.9 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EEQ33015.1 - 1.2e-05 24.7 0.0 0.00015 21.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 EEQ33015.1 - 0.00053 20.0 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EEQ33015.1 - 0.011 14.5 0.2 1.1 7.9 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Mqo PF06039.15 EEQ33015.1 - 0.014 14.0 0.0 3.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 EEQ33015.1 - 0.025 13.7 0.0 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EEQ33015.1 - 0.046 12.8 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EEQ33015.1 - 0.084 11.9 0.0 0.35 9.9 0.0 2.1 2 1 0 2 2 2 0 Lycopene cyclase protein OGG_N PF07934.12 EEQ33016.1 - 1.7e-25 89.5 0.1 3.5e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EEQ33016.1 - 3.7e-16 59.5 0.0 6e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EEQ33016.1 - 0.0003 20.5 0.0 0.00096 18.9 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif RRM_1 PF00076.22 EEQ33017.1 - 1.3e-30 105.1 0.2 5e-13 48.7 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ33017.1 - 8.6e-07 28.7 0.0 0.18 11.7 0.0 3.5 3 0 0 3 3 3 3 Occluded RNA-recognition motif 7tm_2 PF00002.24 EEQ33018.1 - 0.0017 17.7 12.6 0.0036 16.6 12.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1751 PF08551.10 EEQ33018.1 - 0.034 14.7 1.1 0.034 14.7 1.1 2.3 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Chromate_transp PF02417.15 EEQ33019.1 - 5.7e-56 189.0 35.4 1.4e-30 106.5 14.9 2.4 3 0 0 3 3 3 2 Chromate transporter Ribosomal_S13_N PF08069.12 EEQ33020.1 - 3.5e-30 103.8 0.3 5.7e-30 103.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EEQ33020.1 - 2.2e-15 56.6 0.2 3.4e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EEQ33020.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain VRR_NUC PF08774.11 EEQ33021.1 - 4.5e-24 84.6 0.0 1.2e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.13 EEQ33022.1 - 1.6e-13 50.1 0.0 2.2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.22 EEQ33023.1 - 2.7e-19 68.8 0.0 4.5e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ33023.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GlyL_C PF12524.8 EEQ33023.1 - 0.18 11.9 4.7 0.38 10.9 4.7 1.5 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal TMEM65 PF10507.9 EEQ33023.1 - 4.2 7.4 13.2 34 4.4 9.6 2.3 1 1 1 2 2 2 0 Transmembrane protein 65 zf-HC5HC2H_2 PF13832.6 EEQ33024.1 - 1e-31 109.3 2.9 1e-31 109.3 2.9 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 EEQ33024.1 - 2.9e-31 109.0 0.6 1.6e-30 106.6 0.0 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 EEQ33024.1 - 1.2e-27 96.0 0.8 1.2e-27 96.0 0.8 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EEQ33024.1 - 5.4e-14 51.5 2.9 5.4e-14 51.5 2.9 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EEQ33024.1 - 9.5e-09 35.0 23.7 1.1e-08 34.8 9.8 2.6 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.25 EEQ33024.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Bromodomain zf-PHD-like PF15446.6 EEQ33024.1 - 2.2 7.9 12.2 0.016 14.8 2.1 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 EEQ33024.1 - 7.8 6.9 17.0 9.1 6.7 5.2 2.7 2 0 0 2 2 2 0 C1 domain Myb_DNA-bind_6 PF13921.6 EEQ33026.1 - 7.1e-09 35.8 0.8 7.8e-08 32.5 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EEQ33026.1 - 2.2e-06 27.8 0.7 7.9e-06 26.0 0.0 2.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain Peptidase_M22 PF00814.25 EEQ33027.1 - 6.9e-45 153.9 0.0 6.2e-40 137.6 0.0 3.6 2 1 0 2 2 2 2 Glycoprotease family Glyco_transf_25 PF01755.17 EEQ33029.1 - 3.9e-08 33.4 0.0 2.5e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Mid2 PF04478.12 EEQ33030.1 - 0.0029 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor FMO-like PF00743.19 EEQ33031.1 - 5.2e-12 45.0 0.4 1.4e-10 40.3 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EEQ33031.1 - 6.7e-12 45.5 0.0 4.9e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ33031.1 - 1.4e-11 44.2 0.0 2e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ33031.1 - 2.2e-10 40.3 0.0 5.3e-10 39.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ33031.1 - 4.2e-06 26.1 0.0 2.2e-05 23.8 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EEQ33031.1 - 0.00011 22.7 0.1 0.19 12.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ33031.1 - 0.00039 20.4 0.0 7.7 6.5 0.1 3.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EEQ33031.1 - 0.026 14.6 0.0 0.09 12.8 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 EEQ33031.1 - 0.026 14.1 0.3 0.98 8.9 0.0 2.9 2 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EEQ33031.1 - 0.03 13.4 0.0 0.47 9.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EEQ33031.1 - 0.031 13.3 0.0 3.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EEQ33031.1 - 0.1 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 EEQ33031.1 - 0.15 10.7 0.2 8.8 4.9 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 EEQ33031.1 - 0.19 11.0 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 EEQ33033.1 - 1.1e-15 57.7 0.0 6.9e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ33033.1 - 2.8e-05 23.5 0.1 0.31 10.3 0.5 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase MRC1 PF09444.10 EEQ33034.1 - 2.5 8.6 7.1 5.8 7.4 7.1 1.5 1 0 0 1 1 1 0 MRC1-like domain Mito_carr PF00153.27 EEQ33035.1 - 1.1e-73 243.3 0.4 4.3e-25 87.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EEQ33035.1 - 8.7e-14 51.7 4.0 5.1e-09 36.5 0.7 3.5 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EEQ33035.1 - 6.2e-12 44.4 6.9 6.9e-07 28.7 0.1 5.6 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 EEQ33035.1 - 3.7e-11 41.8 9.9 8.4e-07 28.1 0.1 5.6 6 0 0 6 6 6 3 EF hand EF-hand_5 PF13202.6 EEQ33035.1 - 6.6e-07 28.5 2.9 5.7e-05 22.4 0.1 4.0 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 EEQ33035.1 - 3e-06 27.0 1.1 2.6 8.0 0.0 5.0 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_9 PF14658.6 EEQ33035.1 - 0.083 13.2 0.0 23 5.4 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain DUF726 PF05277.12 EEQ33037.1 - 1.5e-91 306.9 0.0 1.9e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_8 PF06259.12 EEQ33037.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase RTC4 PF14474.6 EEQ33038.1 - 2.6e-33 114.7 0.0 4.2e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain Tmemb_14 PF03647.13 EEQ33039.1 - 5.2e-21 75.2 7.4 6.4e-21 74.9 7.4 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DAD PF02109.16 EEQ33040.1 - 1.5e-45 153.9 0.2 2.1e-45 153.5 0.2 1.2 1 0 0 1 1 1 1 DAD family MSA-2c PF12238.8 EEQ33040.1 - 0.74 9.8 4.4 59 3.6 0.0 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c HA2 PF04408.23 EEQ33041.1 - 1.6e-20 73.4 0.0 1.6e-20 73.4 0.0 3.1 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ33041.1 - 8.4e-15 55.1 0.0 2.5e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EEQ33041.1 - 2.6e-09 37.3 0.0 2.5e-07 31.0 0.0 2.7 1 1 1 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EEQ33041.1 - 4.2e-06 26.6 0.2 9.5e-06 25.5 0.2 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEQ33041.1 - 0.00012 22.4 0.1 0.00038 20.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EEQ33041.1 - 0.00022 20.6 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EEQ33041.1 - 0.00076 18.6 0.0 0.0032 16.6 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 EEQ33041.1 - 0.0016 18.2 0.4 0.0035 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEQ33041.1 - 0.0047 17.3 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EEQ33041.1 - 0.0078 15.6 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC SRP54 PF00448.22 EEQ33041.1 - 0.0098 15.5 0.2 0.031 13.9 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EEQ33041.1 - 0.015 15.3 0.1 0.074 13.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EEQ33041.1 - 0.025 14.6 0.0 9.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EEQ33041.1 - 0.058 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Microtub_bd PF16796.5 EEQ33041.1 - 0.094 12.7 0.0 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding Glug PF07581.12 EEQ33041.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 The GLUG motif NACHT PF05729.12 EEQ33041.1 - 0.16 11.8 0.8 1.3 8.9 0.1 2.4 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.6 EEQ33041.1 - 6.7 7.2 7.5 2.4 8.6 0.1 3.0 2 1 1 3 3 3 0 AAA domain DUF5427 PF10310.9 EEQ33043.1 - 5.5e-158 526.7 0.1 7e-158 526.4 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) NUDE_C PF04880.13 EEQ33043.1 - 0.53 10.7 5.3 1.1 9.7 5.3 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF2462 PF09495.10 EEQ33044.1 - 1.3e-23 83.5 13.7 1.3e-23 83.5 13.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) Gly_transf_sug PF04488.15 EEQ33045.1 - 8.4e-11 42.4 0.0 1.8e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EEQ33045.1 - 0.026 13.9 0.1 0.026 13.9 0.1 2.0 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein Borrelia_P83 PF05262.11 EEQ33045.1 - 0.043 12.3 15.7 0.06 11.8 15.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4192 PF13830.6 EEQ33045.1 - 0.052 13.6 0.9 0.072 13.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) NPR3 PF03666.13 EEQ33045.1 - 0.12 11.1 11.2 0.17 10.7 11.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 EEQ33045.1 - 1.9 8.6 5.4 3.1 7.9 5.4 1.4 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 EEQ33045.1 - 3.6 8.0 9.6 8.6 6.8 9.6 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF16 PF01519.16 EEQ33046.1 - 0.00057 20.3 3.5 0.001 19.5 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 Cnn_1N PF07989.11 EEQ33046.1 - 0.034 14.3 4.1 0.096 12.9 4.1 1.8 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF4618 PF15397.6 EEQ33046.1 - 0.05 13.0 6.9 0.09 12.2 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 EEQ33046.1 - 0.15 12.6 0.1 0.36 11.3 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 EEQ33046.1 - 0.23 11.6 17.7 0.089 12.9 13.1 2.2 1 1 1 2 2 2 0 Tropomyosin like Fmp27_WPPW PF10359.9 EEQ33046.1 - 0.23 10.2 5.1 0.1 11.4 1.7 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain HeLo PF14479.6 EEQ33046.1 - 0.51 10.1 5.1 1.3 8.8 5.1 1.6 1 0 0 1 1 1 0 Prion-inhibition and propagation FPP PF05911.11 EEQ33046.1 - 0.67 8.1 12.3 1.3 7.1 12.3 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil GAS PF13851.6 EEQ33046.1 - 0.68 9.3 12.0 2.5 7.4 11.0 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 EEQ33046.1 - 1.2 9.1 11.1 3.8 7.5 4.7 2.6 1 1 1 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 EEQ33046.1 - 1.7 8.8 3.8 4.6 7.4 3.8 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 EEQ33046.1 - 2.1 8.7 8.1 4.6 7.6 7.6 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Golgin_A5 PF09787.9 EEQ33046.1 - 2.2 7.7 15.0 1.1 8.7 12.1 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 VPS38 PF17649.1 EEQ33046.1 - 3 6.6 5.0 4.4 6.1 5.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 ABC_tran_CTD PF16326.5 EEQ33046.1 - 3.5 8.0 21.8 3.2 8.1 6.9 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF3824 PF12868.7 EEQ33047.1 - 3.3 8.4 5.9 5.1 7.8 5.9 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Peptidase_S8 PF00082.22 EEQ33048.1 - 1.8e-17 63.6 0.1 3.7e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Subtilase family WD40 PF00400.32 EEQ33048.1 - 8.3e-15 54.9 12.2 0.008 17.0 0.1 8.2 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33048.1 - 3.4e-13 49.7 0.0 0.0031 17.8 0.0 6.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EEQ33048.1 - 4.7e-10 39.6 0.2 1.6e-08 34.6 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EEQ33048.1 - 4.4e-06 27.2 0.3 2.2e-05 24.9 0.0 2.4 2 1 0 2 2 1 1 AAA ATPase domain Ge1_WD40 PF16529.5 EEQ33048.1 - 1.6e-05 24.0 0.0 0.62 9.0 0.0 3.7 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 EEQ33048.1 - 0.0017 18.6 0.0 0.0056 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain TruB_C PF09142.11 EEQ33048.1 - 0.0032 17.2 0.0 1.4 8.8 0.0 3.8 3 0 0 3 3 3 1 tRNA Pseudouridine synthase II, C terminal ATPase_2 PF01637.18 EEQ33048.1 - 0.0049 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PD40 PF07676.12 EEQ33048.1 - 0.008 16.1 0.0 1.2e+02 2.8 0.0 6.3 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EEQ33048.1 - 0.015 14.7 0.0 8 5.7 0.0 4.2 5 0 0 5 5 5 0 Neuroblastoma-amplified sequence, N terminal AAA PF00004.29 EEQ33048.1 - 0.043 14.2 0.0 0.4 11.1 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DPPIV_N PF00930.21 EEQ33048.1 - 0.12 11.1 0.0 1.8 7.2 0.0 2.7 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region KAP_NTPase PF07693.14 EEQ33048.1 - 0.15 11.3 0.1 0.25 10.5 0.1 1.4 1 0 0 1 1 1 0 KAP family P-loop domain LELP1 PF15042.6 EEQ33048.1 - 1.7 9.1 14.1 3.8 7.9 14.1 1.5 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Fungal_lectin PF07938.12 EEQ33049.1 - 1.4e-09 37.8 3.8 1.5e-05 24.6 0.1 3.0 1 1 2 3 3 3 2 Fungal fucose-specific lectin UCR_Fe-S_N PF10399.9 EEQ33049.1 - 0.023 14.0 4.7 0.049 13.0 4.7 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ETRAMP PF09716.10 EEQ33049.1 - 0.15 12.1 0.3 0.15 12.1 0.3 1.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Epiglycanin_C PF14654.6 EEQ33049.1 - 1 9.4 4.1 1.3 9.2 1.5 2.4 2 1 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Glyco_transf_90 PF05686.12 EEQ33050.1 - 1e-36 126.7 6.2 2.1e-36 125.7 6.2 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 OapA_N PF08525.11 EEQ33050.1 - 0.12 12.3 1.1 0.21 11.6 1.1 1.3 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif GPI-anchored PF10342.9 EEQ33052.1 - 3.3e-26 91.9 0.1 6.1e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family fn3 PF00041.21 EEQ33052.1 - 0.012 15.9 0.7 0.058 13.7 0.3 2.1 2 0 0 2 2 2 0 Fibronectin type III domain DUF4448 PF14610.6 EEQ33052.1 - 0.022 14.5 0.4 0.043 13.6 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) GST_N_3 PF13417.6 EEQ33054.1 - 0.0006 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ33054.1 - 0.0013 18.7 1.3 0.0079 16.2 1.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EEQ33054.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EEQ33054.1 - 0.053 13.8 0.0 0.089 13.1 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Cellulase PF00150.18 EEQ33055.1 - 1.1e-15 57.8 0.0 1.1e-13 51.2 0.0 2.3 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) IBN_N PF03810.19 EEQ33056.1 - 4.4e-14 52.2 0.3 2.9e-13 49.5 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EEQ33056.1 - 0.00073 19.6 0.6 0.037 14.1 0.0 3.4 2 0 0 2 2 2 1 Exportin 1-like protein DUF3385 PF11865.8 EEQ33056.1 - 0.016 15.1 0.9 0.06 13.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Pex2_Pex12 PF04757.14 EEQ33057.1 - 1.9e-27 96.3 1.5 9.1e-27 94.1 1.5 1.9 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EEQ33057.1 - 0.008 16.3 4.2 0.008 16.3 4.2 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EEQ33057.1 - 0.026 14.4 1.4 0.07 13.0 1.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ33057.1 - 0.17 11.8 4.3 0.48 10.3 0.8 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ33057.1 - 0.21 11.6 5.3 1.2 9.2 5.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger DUF1772 PF08592.11 EEQ33058.1 - 3.1e-30 105.3 2.1 4e-30 104.9 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ILVD_EDD PF00920.21 EEQ33059.1 - 2.4e-208 693.0 1.9 2.8e-208 692.8 1.9 1.0 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_6 PF12697.7 EEQ33060.1 - 6.2e-16 59.7 1.9 1.1e-15 58.9 1.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ33060.1 - 2.7e-14 53.4 0.1 1.8e-12 47.5 0.2 2.6 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ33060.1 - 8.5e-12 44.8 0.0 3.1e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 EEQ33060.1 - 2.1e-10 40.5 0.0 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 EEQ33060.1 - 0.00069 19.8 0.2 0.0012 19.1 0.2 1.3 1 0 0 1 1 1 1 Thioesterase domain Y_phosphatase PF00102.27 EEQ33060.1 - 0.0014 18.2 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EEQ33060.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Ser_hydrolase PF06821.13 EEQ33060.1 - 0.0021 18.0 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.13 EEQ33060.1 - 0.0031 17.2 0.0 0.09 12.5 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein LCAT PF02450.15 EEQ33060.1 - 0.0041 16.3 0.0 0.048 12.8 0.0 2.2 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 EEQ33060.1 - 0.052 13.1 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2239 PF09998.9 EEQ33060.1 - 0.12 12.2 0.6 0.2 11.4 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF900 PF05990.12 EEQ33060.1 - 0.2 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ribosomal_S19e PF01090.19 EEQ33061.1 - 1.7e-58 196.2 0.2 1.9e-58 196.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF5481 PF17578.2 EEQ33062.1 - 0.32 11.4 1.5 0.75 10.2 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5481) Aldo_ket_red PF00248.21 EEQ33063.1 - 1.2e-34 119.9 0.0 3.8e-32 111.7 0.0 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family eRF1_1 PF03463.15 EEQ33064.1 - 5.8e-45 152.4 0.0 2.2e-44 150.6 0.0 1.9 1 1 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EEQ33064.1 - 4.4e-18 65.8 0.0 7.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EEQ33064.1 - 1.3e-16 61.2 0.0 8.5e-16 58.5 0.0 2.1 1 1 0 1 1 1 1 eRF1 domain 2 Myb_DNA-bind_4 PF13837.6 EEQ33065.1 - 0.00057 20.2 4.0 0.0052 17.1 1.2 2.5 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EEQ33065.1 - 0.073 14.1 4.1 0.93 10.5 0.4 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain PXPV PF12778.7 EEQ33065.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 PXPV repeat (3 copies) Myb_DNA-binding PF00249.31 EEQ33066.1 - 0.00015 21.9 0.0 0.00025 21.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EEQ33068.1 - 3e-15 56.1 3.0 5e-09 36.2 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ33068.1 - 1.8e-09 37.7 0.9 3.8e-06 27.1 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EEQ33068.1 - 1.6 8.7 5.8 0.13 12.1 0.9 1.8 2 0 0 2 2 2 0 Myb DNA-binding like COX5B PF01215.19 EEQ33069.1 - 7e-55 184.2 0.0 9.2e-55 183.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 EEQ33069.1 - 0.095 12.5 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Myb_DNA-bind_6 PF13921.6 EEQ33070.1 - 8.7e-13 48.3 0.0 6.6e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EEQ33070.1 - 1.6e-10 41.0 0.1 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF3486 PF11985.8 EEQ33071.1 - 0.094 13.1 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) CTP_synth_N PF06418.14 EEQ33072.1 - 8.1e-108 359.7 0.0 1.1e-107 359.2 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EEQ33072.1 - 2.2e-55 187.4 0.0 3.4e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EEQ33072.1 - 5.3e-06 26.4 0.2 3.1e-05 23.8 0.2 2.3 2 1 0 2 2 2 1 Peptidase C26 APH PF01636.23 EEQ33073.1 - 0.0015 18.5 0.0 0.0038 17.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family PROCN PF08083.11 EEQ33074.1 - 1.9e-215 715.2 14.8 9.7e-215 712.9 9.9 3.0 2 1 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EEQ33074.1 - 1.1e-126 421.1 2.6 2e-126 420.3 2.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EEQ33074.1 - 6.9e-84 279.6 1.0 4.5e-57 192.4 0.1 3.1 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EEQ33074.1 - 2.2e-81 271.2 1.8 7.5e-81 269.5 1.8 2.0 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EEQ33074.1 - 1.5e-70 235.4 0.1 3.3e-70 234.4 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EEQ33074.1 - 1e-48 164.3 0.1 3.1e-48 162.8 0.1 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 EEQ33074.1 - 3.5e-48 161.9 0.3 9.7e-48 160.5 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 EEQ33074.1 - 7.7e-10 39.1 0.0 7.7e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Hom_end-associated Hint Hom_end PF05204.14 EEQ33074.1 - 0.00047 20.3 0.0 0.021 15.0 0.0 2.8 2 0 0 2 2 2 1 Homing endonuclease Ribosomal_L34e PF01199.18 EEQ33075.1 - 8.8e-43 144.6 2.8 1.3e-42 144.0 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 EEQ33075.1 - 0.032 13.6 1.3 0.044 13.2 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 EEQ33075.1 - 0.45 10.5 4.5 3.5 7.7 0.3 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain XLF PF09302.11 EEQ33076.1 - 8.4e-54 182.4 0.1 8.4e-54 182.4 0.1 1.8 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Cactin_mid PF10312.9 EEQ33077.1 - 1.6e-65 220.6 5.8 1.6e-65 220.6 5.8 1.7 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EEQ33077.1 - 6.9e-57 190.8 6.5 1.4e-56 189.8 6.5 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Forkhead PF00250.18 EEQ33078.1 - 7.2e-20 71.1 0.2 1.4e-19 70.2 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain WD40 PF00400.32 EEQ33080.1 - 2.4e-14 53.5 12.7 5.3e-06 27.1 0.4 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33080.1 - 2.2e-06 27.9 0.0 0.81 10.0 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Zn_ribbon_17 PF17120.5 EEQ33080.1 - 0.0064 16.1 7.7 0.02 14.5 7.7 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type eIF2A PF08662.11 EEQ33080.1 - 0.0066 16.3 0.0 0.076 12.9 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EEQ33080.1 - 0.022 14.7 1.7 0.12 12.3 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Tox-URI2 PF15653.6 EEQ33081.1 - 0.024 14.9 0.0 4.3 7.7 0.0 2.5 2 0 0 2 2 2 0 URI fold toxin 2 ABC_tran PF00005.27 EEQ33082.1 - 1.1e-32 113.4 0.0 2.7e-32 112.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 EEQ33082.1 - 2.8e-29 102.6 12.3 1.2e-14 54.6 6.9 2.8 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EEQ33082.1 - 3e-07 30.1 0.2 1.1e-05 25.0 0.0 2.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EEQ33082.1 - 0.014 15.6 0.7 0.34 11.2 0.7 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EEQ33082.1 - 0.016 15.5 0.3 0.13 12.5 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EEQ33082.1 - 0.055 13.2 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ33082.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EEQ33082.1 - 0.099 13.0 0.7 0.4 11.0 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain DUF498 PF04430.14 EEQ33083.1 - 2.4e-31 108.0 0.0 3.8e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.20 EEQ33084.1 - 4.6e-107 358.5 0.0 5.6e-107 358.3 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EEQ33084.1 - 0.00012 21.6 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Glyco_hydro_16 PF00722.21 EEQ33085.1 - 2.6e-44 150.8 2.5 4.2e-44 150.1 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GFA PF04828.14 EEQ33086.1 - 0.007 16.7 0.2 0.014 15.7 0.2 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pro_dh PF01619.18 EEQ33088.1 - 1.2e-61 208.8 0.0 1.6e-61 208.4 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase AP-5_subunit_s1 PF15001.6 EEQ33088.1 - 0.17 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 PMSR PF01625.21 EEQ33089.1 - 1.4e-58 197.4 0.1 1.7e-58 197.1 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF2417 PF10329.9 EEQ33090.1 - 4.6e-78 261.9 0.2 6.4e-78 261.4 0.2 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF1345 PF07077.11 EEQ33090.1 - 0.66 9.7 4.6 0.14 11.9 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Trp_oprn_chp PF09534.10 EEQ33090.1 - 1 9.1 5.9 0.18 11.6 0.8 2.2 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Abhydrolase_6 PF12697.7 EEQ33091.1 - 1.7e-21 77.9 0.1 2.3e-21 77.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ33091.1 - 2.6e-08 33.8 0.0 4.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ33091.1 - 8.2e-06 25.2 0.1 1.5e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EEQ33091.1 - 0.096 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 EEQ33091.1 - 0.18 11.9 0.1 1.4 8.9 0.1 2.2 1 1 0 1 1 1 0 Thioesterase domain WD40 PF00400.32 EEQ33092.1 - 2.1e-48 161.3 26.7 1.1e-08 35.6 0.3 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EEQ33092.1 - 3.6e-35 121.0 0.2 5.1e-35 120.5 0.2 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EEQ33092.1 - 3.2e-14 53.0 0.2 0.0089 16.3 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ33092.1 - 1.5e-07 30.5 1.0 0.00018 20.3 0.1 3.9 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ33092.1 - 0.0002 20.4 0.2 0.016 14.2 0.0 3.1 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 EEQ33092.1 - 0.00043 20.1 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 EEQ33092.1 - 0.0021 16.9 0.3 0.51 9.0 0.0 2.9 2 1 1 3 3 3 2 Nup133 N terminal like eIF2A PF08662.11 EEQ33092.1 - 0.0068 16.3 0.2 0.035 14.0 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EEQ33092.1 - 0.069 12.5 0.2 55 2.9 0.0 3.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF4550 PF15084.6 EEQ33092.1 - 0.07 13.6 0.0 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) PALB2_WD40 PF16756.5 EEQ33092.1 - 0.87 8.4 5.5 0.13 11.2 0.9 1.8 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Med11 PF10280.9 EEQ33093.1 - 5.3e-42 143.5 0.0 7.1e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Mediator complex protein F_actin_cap_B PF01115.17 EEQ33094.1 - 2.9e-105 351.2 0.0 3.4e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit ResIII PF04851.15 EEQ33095.1 - 3.1e-20 72.9 0.0 6.5e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ33095.1 - 7.1e-20 71.4 0.1 2e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ33095.1 - 8.9e-15 54.9 0.0 2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EEQ33095.1 - 0.003 17.2 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EEQ33095.1 - 0.0046 16.2 0.0 0.0084 15.3 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase V-ATPase_G PF03179.15 EEQ33097.1 - 6.2e-21 74.9 11.6 7.9e-21 74.6 11.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 EEQ33097.1 - 0.00066 20.1 4.8 0.00098 19.5 4.8 1.3 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit AAA_15 PF13175.6 EEQ33097.1 - 0.017 14.9 7.4 0.02 14.6 7.4 1.0 1 0 0 1 1 1 0 AAA ATPase domain Eno-Rase_FAD_bd PF07055.12 EEQ33097.1 - 0.043 14.2 0.8 0.075 13.5 0.8 1.3 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Borrelia_P83 PF05262.11 EEQ33097.1 - 0.57 8.6 12.9 0.62 8.5 12.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4337 PF14235.6 EEQ33097.1 - 4.9 7.2 8.1 6.4 6.9 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ATP-synt_B PF00430.18 EEQ33097.1 - 9.6 6.3 12.1 48 4.0 12.1 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) PET117 PF15786.5 EEQ33098.1 - 1.8e-26 92.2 1.3 2.1e-26 92.0 1.3 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial RPA_interact_M PF14767.6 EEQ33098.1 - 0.066 13.8 1.7 0.083 13.5 1.7 1.2 1 0 0 1 1 1 0 Replication protein A interacting middle THEG4 PF15834.5 EEQ33098.1 - 0.15 12.0 0.1 0.2 11.6 0.1 1.3 1 1 0 1 1 1 0 Testis highly expressed protein 4 DivIVA PF05103.13 EEQ33099.1 - 0.0012 18.9 22.2 0.027 14.5 6.6 3.7 2 1 1 3 3 3 2 DivIVA protein DUF4407 PF14362.6 EEQ33099.1 - 0.0023 17.3 3.1 0.0023 17.3 3.1 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) HAP1_N PF04849.13 EEQ33099.1 - 0.048 12.9 36.2 0.079 12.1 0.3 2.6 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Bacillus_HBL PF05791.11 EEQ33099.1 - 0.39 10.5 10.4 2.1 8.1 0.2 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) AAA_27 PF13514.6 EEQ33099.1 - 0.69 9.5 6.9 1.6 8.3 6.9 1.6 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 EEQ33099.1 - 1.3 9.2 20.9 3.7 7.7 6.7 3.6 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family TBCC PF07986.12 EEQ33100.1 - 3.9e-27 94.4 1.6 6.3e-27 93.7 1.6 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EEQ33100.1 - 1.3e-09 38.5 0.0 2.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain DUF1431 PF07248.12 EEQ33100.1 - 0.0031 17.8 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1431) RTX PF02382.15 EEQ33100.1 - 0.049 13.3 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein JAB PF01398.21 EEQ33101.1 - 1.1e-14 54.4 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EEQ33101.1 - 2.5e-05 24.4 0.0 4.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 EEQ33101.1 - 6e-05 22.8 0.0 0.00018 21.2 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3439 PF11921.8 EEQ33101.1 - 1.8 8.6 11.4 0.22 11.5 1.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SPX PF03105.19 EEQ33103.1 - 4.8 7.0 16.5 6.5 6.6 16.5 1.2 1 0 0 1 1 1 0 SPX domain Vps8 PF12816.7 EEQ33104.1 - 4.6e-65 218.9 1.1 9e-65 217.9 0.1 2.0 2 1 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EEQ33104.1 - 5.4e-10 39.3 1.0 0.00022 21.1 0.1 2.9 2 1 0 2 2 2 2 Region in Clathrin and VPS Pox_D3 PF04580.13 EEQ33104.1 - 0.0025 17.5 0.1 0.0049 16.5 0.1 1.4 1 0 0 1 1 1 1 Chordopoxvirinae D3 protein WD40 PF00400.32 EEQ33104.1 - 0.022 15.6 0.1 0.1 13.5 0.1 2.3 1 0 0 1 1 1 0 WD domain, G-beta repeat YqzH PF14164.6 EEQ33104.1 - 0.024 14.7 0.1 9 6.5 0.0 2.8 2 0 0 2 2 2 0 YqzH-like protein zf-C3H2C3 PF17122.5 EEQ33104.1 - 0.14 12.2 0.1 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger zf-rbx1 PF12678.7 EEQ33104.1 - 0.18 12.1 0.0 0.7 10.2 0.0 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEQ33104.1 - 0.44 10.9 1.3 1.2 9.5 0.0 2.4 3 0 0 3 3 3 0 Ring finger domain HNH_2 PF13391.6 EEQ33105.1 - 1.8e-07 31.2 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease D5_N PF08706.11 EEQ33105.1 - 0.16 12.2 0.2 0.95 9.7 0.0 2.0 2 0 0 2 2 2 0 D5 N terminal like Glyco_hydro_16 PF00722.21 EEQ33106.1 - 3.2e-08 33.2 0.4 6.6e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_transf_90 PF05686.12 EEQ33107.1 - 5.3e-14 51.9 0.1 6.7e-07 28.6 0.0 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 GNAT_acetyltr_2 PF13718.6 EEQ33108.1 - 8.6e-99 329.5 0.0 1.5e-98 328.8 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EEQ33108.1 - 3.3e-92 308.4 0.0 5.8e-92 307.7 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EEQ33108.1 - 1.6e-64 217.0 0.0 4.1e-64 215.7 0.0 1.7 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EEQ33108.1 - 1.1e-34 118.3 0.0 2.8e-34 116.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EEQ33108.1 - 0.00035 20.3 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ33108.1 - 0.017 15.4 0.0 0.33 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 EEQ33108.1 - 0.037 14.2 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Thioredoxin PF00085.20 EEQ33109.1 - 4.6e-28 97.2 0.0 1.3e-22 79.7 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EEQ33109.1 - 1e-07 32.3 0.4 0.00082 19.8 0.1 2.7 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EEQ33109.1 - 0.00037 20.8 0.0 1.9 8.9 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 EEQ33109.1 - 0.00039 19.9 0.0 0.015 14.7 0.0 2.2 1 1 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EEQ33109.1 - 0.003 17.5 0.0 0.027 14.4 0.0 2.3 3 0 0 3 3 3 1 AhpC/TSA family AsnC_trans_reg2 PF17805.1 EEQ33109.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AsnC-like ligand binding domain NPR3 PF03666.13 EEQ33109.1 - 0.18 10.6 4.0 0.3 9.8 4.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TraF PF13728.6 EEQ33109.1 - 0.22 11.3 0.0 0.22 11.3 0.0 4.2 4 0 0 4 4 4 0 F plasmid transfer operon protein CCDC53 PF10152.9 EEQ33109.1 - 0.25 11.7 8.0 1.4 9.3 1.7 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF913 PF06025.12 EEQ33109.1 - 8.2 5.3 7.7 1.7 7.5 3.9 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) ATP-synt PF00231.19 EEQ33110.1 - 1.1e-76 258.2 4.4 1.3e-76 258.0 4.4 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I PF01028.20 EEQ33111.1 - 2.1e-98 328.2 4.6 2.1e-98 328.2 4.6 2.5 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EEQ33111.1 - 1.6e-95 318.7 2.4 1.6e-95 318.7 2.4 4.0 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EEQ33111.1 - 3.6e-32 110.1 1.0 3.6e-32 110.1 1.0 2.6 2 0 0 2 2 2 1 C-terminal topoisomerase domain PikAIV_N PF18605.1 EEQ33111.1 - 0.93 9.1 5.3 0.33 10.6 1.7 2.2 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Epimerase PF01370.21 EEQ33112.1 - 8.5e-18 64.7 0.0 1.2e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ33112.1 - 6.8e-08 31.8 0.0 2.2e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EEQ33112.1 - 1.5e-06 27.5 0.0 2.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EEQ33112.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EEQ33112.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EEQ33112.1 - 0.0069 16.6 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 EEQ33112.1 - 0.14 12.3 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 EEQ33112.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 KR domain Vta1 PF04652.16 EEQ33114.1 - 1.6e-55 187.0 5.7 1.6e-55 187.0 5.7 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EEQ33114.1 - 3e-19 68.4 0.3 8.3e-19 67.0 0.3 1.8 1 0 0 1 1 1 1 Vta1 C-terminal domain Peptidase_C2 PF00648.21 EEQ33115.1 - 1.5e-29 103.0 0.0 2.2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EEQ33115.1 - 4.7e-08 33.4 0.1 1.3e-05 25.4 0.1 3.2 2 1 0 2 2 2 1 Calpain large subunit, domain III Mito_carr PF00153.27 EEQ33116.1 - 1e-58 195.3 1.0 1.3e-22 79.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CbiM PF01891.16 EEQ33116.1 - 0.012 15.5 0.3 0.42 10.4 0.1 2.5 3 0 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region DUF3147 PF11345.8 EEQ33116.1 - 0.05 14.0 1.6 0.075 13.4 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) IncD PF17628.2 EEQ33116.1 - 0.099 12.4 0.1 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Inclusion membrane protein D SNase PF00565.17 EEQ33117.1 - 1.1e-22 80.6 0.0 1.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ADK PF00406.22 EEQ33118.1 - 4.5e-35 121.0 0.0 7.1e-19 68.4 0.1 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EEQ33118.1 - 2.5e-16 59.3 0.0 4.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EEQ33118.1 - 6.5e-14 52.5 0.0 1.6e-09 38.3 0.1 2.4 2 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EEQ33118.1 - 4e-05 24.2 0.0 0.00033 21.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ33118.1 - 0.002 18.3 0.0 0.0082 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEQ33118.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EEQ33118.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EEQ33118.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 EEQ33118.1 - 0.17 10.8 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_primase_lrg PF04104.14 EEQ33119.1 - 7.8e-85 284.5 0.0 1.1e-84 284.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sec23_trunk PF04811.15 EEQ33120.1 - 3.6e-78 262.5 0.0 5.3e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EEQ33120.1 - 8.3e-29 100.2 0.0 1.7e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EEQ33120.1 - 5.8e-25 87.1 0.2 1.4e-24 85.8 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EEQ33120.1 - 1.4e-14 53.9 4.5 2.6e-14 53.0 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EEQ33120.1 - 1.2e-11 44.4 0.0 3e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EEQ33120.1 - 0.15 11.5 1.7 0.18 11.2 0.4 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L11_N PF03946.14 EEQ33121.1 - 8e-21 73.6 0.2 2.1e-20 72.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EEQ33121.1 - 5.4e-15 55.7 0.1 9.1e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_transf_41 PF13844.6 EEQ33124.1 - 3.2e-102 342.4 0.1 2.1e-52 178.2 0.0 3.2 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_11 PF13414.6 EEQ33124.1 - 7.5e-18 63.9 16.0 0.0004 20.0 0.0 6.3 3 2 3 6 6 6 4 TPR repeat TPR_1 PF00515.28 EEQ33124.1 - 1.6e-15 56.1 12.9 0.0042 16.8 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ33124.1 - 9.8e-15 53.4 14.6 0.0071 16.4 0.2 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ33124.1 - 8.6e-10 38.1 10.0 0.011 15.9 0.0 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ33124.1 - 5e-09 36.7 13.5 0.0084 16.7 0.9 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ33124.1 - 1.1e-08 34.6 14.6 0.037 13.9 0.0 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ33124.1 - 1.2e-08 34.7 4.4 0.63 10.6 0.1 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ33124.1 - 5.7e-08 32.9 7.9 0.045 14.6 0.0 5.9 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ33124.1 - 8.5e-08 32.4 8.9 0.0044 17.3 0.2 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ33124.1 - 4e-06 27.3 11.9 0.00072 20.0 0.5 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ33124.1 - 8.3e-05 22.3 6.5 0.75 10.0 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat BTAD PF03704.17 EEQ33124.1 - 0.00022 21.7 1.8 0.13 12.7 0.0 3.1 2 0 0 2 2 2 2 Bacterial transcriptional activator domain ANAPC3 PF12895.7 EEQ33124.1 - 0.00024 21.2 0.5 0.003 17.7 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EEQ33124.1 - 0.011 15.0 4.6 0.31 10.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ33124.1 - 0.31 11.2 7.0 0.51 10.5 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 EEQ33126.1 - 1.9e-26 92.0 1.9 8.7e-15 54.6 0.1 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ33126.1 - 1.3e-18 67.0 6.6 5.4e-14 52.2 0.1 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF2774 PF11242.8 EEQ33126.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) HTH_23 PF13384.6 EEQ33126.1 - 0.14 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Myb_DNA-bind_4 PF13837.6 EEQ33126.1 - 0.45 10.9 0.0 0.45 10.9 0.0 2.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain ABC_tran PF00005.27 EEQ33128.1 - 1.6e-47 161.5 0.0 8.6e-29 100.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ33128.1 - 4.8e-30 105.1 27.8 1.9e-21 76.9 9.1 2.8 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EEQ33128.1 - 6.1e-10 38.9 3.0 0.00093 18.7 0.1 4.6 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ33128.1 - 2.7e-05 23.8 0.8 0.12 12.1 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EEQ33128.1 - 7.5e-05 23.3 0.1 0.45 11.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EEQ33128.1 - 0.00015 22.1 0.4 0.83 9.9 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 EEQ33128.1 - 0.00043 20.7 0.7 0.24 11.7 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EEQ33128.1 - 0.0017 17.4 0.2 0.31 10.0 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EEQ33128.1 - 0.0034 17.0 0.0 3.1 7.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EEQ33128.1 - 0.004 17.3 4.0 0.08 13.0 0.2 2.8 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_21 PF13304.6 EEQ33128.1 - 0.0051 16.7 5.8 0.53 10.0 0.4 4.0 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 EEQ33128.1 - 0.0091 15.2 0.1 4.2 6.5 0.1 3.1 3 0 0 3 3 3 1 NB-ARC domain RsgA_GTPase PF03193.16 EEQ33128.1 - 0.014 15.3 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 EEQ33128.1 - 0.018 15.1 1.5 0.18 11.9 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EEQ33128.1 - 0.048 13.4 0.1 18 5.0 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 EEQ33128.1 - 0.074 13.3 0.5 31 4.9 0.0 4.1 4 0 0 4 4 4 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 EEQ33128.1 - 0.076 13.6 0.2 2.1 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EEQ33128.1 - 0.08 12.7 0.0 0.52 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EEQ33128.1 - 0.082 13.1 0.0 13 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EEQ33128.1 - 0.11 11.9 0.1 10 5.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 EEQ33128.1 - 0.11 12.9 0.4 48 4.4 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_7 PF12775.7 EEQ33128.1 - 0.17 11.3 0.2 21 4.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_A32 PF04665.12 EEQ33128.1 - 0.45 9.9 1.7 1.6 8.1 0.1 2.6 3 0 0 3 3 3 0 Poxvirus A32 protein NACHT PF05729.12 EEQ33128.1 - 0.6 10.0 3.9 29 4.5 0.1 3.6 3 0 0 3 3 3 0 NACHT domain FAM176 PF14851.6 EEQ33128.1 - 9.3 5.9 6.2 5.8 6.6 1.5 2.6 3 0 0 3 3 3 0 FAM176 family Cu-oxidase_3 PF07732.15 EEQ33129.1 - 3.3e-11 43.3 1.1 4.4e-08 33.2 0.2 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EEQ33129.1 - 4.1e-10 39.5 0.1 0.00055 19.7 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EEQ33129.1 - 0.00099 19.3 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Copper-bind PF00127.20 EEQ33129.1 - 0.14 12.7 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family NCBP3 PF10309.9 EEQ33130.1 - 1.1e-24 86.0 0.1 1.8e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Ribosomal_L29e PF01779.17 EEQ33131.1 - 6e-22 77.7 12.6 9e-22 77.1 12.6 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family ATP-synt_DE_N PF02823.16 EEQ33132.1 - 2.5e-15 56.1 0.0 3.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF3824 PF12868.7 EEQ33133.1 - 0.011 16.5 1.5 0.011 16.5 1.5 5.6 3 2 1 4 4 4 0 Domain of unknwon function (DUF3824) Cytochrom_B561 PF03188.16 EEQ33133.1 - 0.019 15.1 9.9 0.038 14.1 9.9 1.4 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 Corona_nucleoca PF00937.18 EEQ33133.1 - 0.046 12.8 7.6 0.1 11.6 7.6 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Rib_recp_KP_reg PF05104.12 EEQ33133.1 - 0.32 12.0 15.1 0.43 11.6 8.1 2.2 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region APH PF01636.23 EEQ33134.1 - 1.5e-42 146.2 0.2 6.8e-42 144.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ33134.1 - 3.1e-05 23.4 0.0 0.00018 20.9 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EEQ33134.1 - 0.00031 20.1 0.1 0.00064 19.1 0.1 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 EEQ33134.1 - 0.0032 17.1 0.0 0.056 13.0 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 EEQ33134.1 - 0.029 13.6 0.0 0.32 10.2 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase DUF1679 PF07914.11 EEQ33134.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) zf-C2H2 PF00096.26 EEQ33136.1 - 6.6e-08 32.6 10.1 0.0061 16.9 2.4 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ33136.1 - 0.00025 21.3 7.1 1.8 9.1 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain PQ-loop PF04193.14 EEQ33137.1 - 5.6e-30 102.9 15.4 9e-18 63.8 1.3 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF3429 PF11911.8 EEQ33137.1 - 0.025 14.9 1.8 0.043 14.1 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3429) DUF202 PF02656.15 EEQ33137.1 - 0.21 12.0 1.3 1.1 9.8 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) SPATA9 PF15824.5 EEQ33137.1 - 0.23 10.7 0.0 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 dUTPase PF00692.19 EEQ33138.1 - 9.2e-46 154.7 0.0 1.2e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 EEQ33138.1 - 0.01 14.7 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.12 EEQ33139.1 - 8e-11 41.8 0.0 1.2e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EEQ33139.1 - 1.4e-06 27.9 0.0 2.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 pfkB family carbohydrate kinase BON PF04972.17 EEQ33139.1 - 0.0081 16.5 0.3 0.82 10.0 0.0 2.6 2 0 0 2 2 2 1 BON domain Mitoc_L55 PF09776.9 EEQ33139.1 - 0.16 11.7 2.2 0.19 11.5 0.5 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 Formyl_trans_N PF00551.19 EEQ33140.1 - 9.8e-40 136.2 0.0 1.1e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Flagellin_IN PF07196.13 EEQ33140.1 - 0.1 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Flagellin hook IN motif Erf4 PF10256.9 EEQ33140.1 - 0.15 12.2 0.0 7.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family ADIP PF11559.8 EEQ33141.1 - 4.4e-39 134.0 10.8 4.4e-39 134.0 10.8 2.4 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EEQ33141.1 - 0.0017 17.9 9.9 0.0017 17.9 9.9 2.5 3 0 0 3 3 3 1 Golgin subfamily A member 5 Spore_III_AF PF09581.10 EEQ33141.1 - 0.0088 16.1 0.5 0.026 14.6 0.4 1.8 1 1 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) TTRAP PF14203.6 EEQ33141.1 - 0.064 13.2 0.2 0.38 10.8 0.2 2.3 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Spc7 PF08317.11 EEQ33141.1 - 0.073 11.9 14.2 0.39 9.5 7.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 EEQ33141.1 - 0.096 12.5 11.9 0.031 14.1 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 EEQ33141.1 - 0.21 10.9 19.2 0.033 13.5 9.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4795 PF16043.5 EEQ33141.1 - 0.68 9.5 14.3 0.23 11.1 5.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 EEQ33141.1 - 1.4 9.1 15.1 1.2 9.3 8.3 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 EEQ33141.1 - 1.6 9.1 13.2 0.43 10.9 6.9 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein DivIVA PF05103.13 EEQ33141.1 - 1.7 8.7 10.7 0.35 10.9 6.0 2.3 2 1 0 2 2 2 0 DivIVA protein TMPIT PF07851.13 EEQ33141.1 - 7.7 5.7 10.7 4.5 6.4 6.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein SAM_2 PF07647.17 EEQ33142.1 - 1.7e-07 31.2 0.1 3.6e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EEQ33142.1 - 0.0028 18.1 0.1 0.0066 16.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 EEQ33142.1 - 0.036 14.3 0.4 0.13 12.6 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) MerR-DNA-bind PF09278.11 EEQ33142.1 - 0.17 12.4 1.5 1.9 9.1 0.9 2.8 2 0 0 2 2 2 0 MerR, DNA binding Pyr_redox_2 PF07992.14 EEQ33143.1 - 1.9e-54 184.9 0.4 2.5e-54 184.5 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EEQ33143.1 - 5.9e-17 61.4 0.0 1.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EEQ33143.1 - 9.2e-17 61.4 1.0 3.3e-14 53.2 0.7 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ33143.1 - 1.3e-07 31.2 0.3 0.00015 21.2 0.3 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ33143.1 - 5.7e-06 25.7 0.0 0.085 12.0 0.0 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.6 EEQ33143.1 - 1.4e-05 25.6 0.0 3.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 EEQ33143.1 - 3e-05 23.9 0.0 8.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 EEQ33143.1 - 4.5e-05 23.5 0.1 0.44 10.5 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding DUF1188 PF06690.11 EEQ33143.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_7 PF13241.6 EEQ33143.1 - 0.0025 18.2 0.3 0.8 10.2 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 EEQ33143.1 - 0.0078 15.0 0.9 0.87 8.2 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein FIST PF08495.10 EEQ33143.1 - 0.0078 16.2 0.2 0.032 14.3 0.1 2.0 2 0 0 2 2 2 1 FIST N domain Amino_oxidase PF01593.24 EEQ33143.1 - 0.096 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 EEQ33143.1 - 0.14 12.4 0.4 8.6 6.7 0.2 2.9 3 0 0 3 3 2 0 TrkA-N domain APH PF01636.23 EEQ33144.1 - 9.7e-05 22.4 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_S3 PF00944.19 EEQ33145.1 - 6.6e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Alphavirus core protein Peptidase_S64 PF08192.11 EEQ33145.1 - 0.00066 18.3 0.8 0.00078 18.1 0.0 1.4 2 0 0 2 2 2 1 Peptidase family S64 Peptidase_S32 PF05579.13 EEQ33145.1 - 0.03 13.5 0.1 0.053 12.7 0.1 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Arrestin_N PF00339.29 EEQ33147.1 - 0.0006 19.9 0.0 0.0048 17.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EEQ33147.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus Menin PF05053.13 EEQ33148.1 - 0.33 9.2 5.7 0.37 9.1 5.7 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 EEQ33148.1 - 0.88 8.0 4.0 0.89 8.0 4.0 1.0 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 EEQ33148.1 - 1.7 8.5 5.2 1.8 8.4 5.2 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EEQ33148.1 - 8.5 5.1 5.6 9.2 5.0 5.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain ACPS PF01648.20 EEQ33149.1 - 2.2e-13 50.3 0.0 2.7e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EEQ33149.1 - 0.04 14.0 2.6 0.89 9.7 2.6 2.4 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain APH PF01636.23 EEQ33150.1 - 3e-14 53.5 0.0 7.4e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ33150.1 - 0.04 13.5 0.0 0.095 12.3 0.0 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EEQ33150.1 - 0.056 12.3 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 EEQ33150.1 - 0.12 11.7 0.0 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.22 EEQ33150.1 - 0.13 11.8 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 RIO1 family HD PF01966.22 EEQ33151.1 - 0.0015 18.7 0.6 0.034 14.4 0.1 2.6 2 1 0 2 2 2 1 HD domain RMI1_C PF16099.5 EEQ33151.1 - 0.028 14.3 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold PDEase_I PF00233.19 EEQ33151.1 - 0.028 14.1 0.1 0.049 13.4 0.1 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase HflK_N PF12221.8 EEQ33151.1 - 0.19 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Coatomer_WDAD PF04053.14 EEQ33152.1 - 0.047 12.7 0.1 0.099 11.7 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region MA3 PF02847.17 EEQ33153.1 - 3.1e-27 94.8 0.1 8.1e-27 93.4 0.1 1.8 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EEQ33153.1 - 1.1e-11 44.8 0.1 2e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain DNA_pol_phi PF04931.13 EEQ33153.1 - 3.8 5.5 11.7 6.6 4.7 11.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi RRM_1 PF00076.22 EEQ33155.1 - 3.4e-17 62.0 0.0 3.3e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EEQ33155.1 - 0.00025 21.0 0.1 0.013 15.6 0.2 2.5 2 0 0 2 2 2 1 Limkain b1 Ribosomal_L7Ae PF01248.26 EEQ33158.1 - 1.6e-24 85.5 0.0 1.8e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family COesterase PF00135.28 EEQ33159.1 - 2.1e-57 195.2 0.0 3.3e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EEQ33159.1 - 7.8e-07 29.2 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ33159.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family SPA PF08616.10 EEQ33160.1 - 5e-37 126.3 0.0 8.1e-37 125.7 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EEQ33160.1 - 1e-32 113.4 0.1 2.1e-32 112.4 0.1 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EEQ33160.1 - 2.3e-07 29.8 0.0 0.066 11.9 0.0 3.5 2 1 1 3 3 3 3 Transport protein Avl9 EF-hand_6 PF13405.6 EEQ33161.1 - 3.4e-13 48.4 2.9 1.9e-05 24.2 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EEQ33161.1 - 8.1e-12 43.8 1.6 7.7e-05 22.0 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EEQ33161.1 - 1.6e-09 38.0 0.5 0.0008 19.8 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EEQ33161.1 - 4.1e-07 29.2 4.1 0.0044 16.5 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EEQ33161.1 - 3.1e-06 26.9 0.6 0.042 13.7 0.0 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EEQ33161.1 - 0.00019 21.7 0.0 0.81 10.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain RabGAP-TBC PF00566.18 EEQ33162.1 - 6.6e-30 104.4 0.0 4.8e-29 101.5 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 EEQ33164.1 - 1.7e-21 76.1 12.2 3.4e-06 27.7 0.2 6.2 5 0 0 5 5 5 5 WD domain, G-beta repeat SET PF00856.28 EEQ33164.1 - 1.6e-08 35.1 0.0 4.7e-07 30.4 0.0 3.3 3 1 0 3 3 3 1 SET domain ANAPC4_WD40 PF12894.7 EEQ33164.1 - 0.0018 18.6 0.1 0.032 14.5 0.0 2.9 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-MYND PF01753.18 EEQ33164.1 - 0.17 12.0 4.9 0.41 10.8 4.9 1.7 1 0 0 1 1 1 0 MYND finger ECH_1 PF00378.20 EEQ33165.1 - 0.48 9.7 3.0 0.61 9.3 1.7 1.7 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase Glucosamine_iso PF01182.20 EEQ33166.1 - 4.5e-67 226.2 0.0 5.1e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Attacin_N PF03768.15 EEQ33166.1 - 0.12 12.5 0.0 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Attacin, N-terminal region LolB PF03550.14 EEQ33167.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB DNA_mis_repair PF01119.19 EEQ33168.1 - 1.5e-11 44.0 0.0 4.8e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EEQ33168.1 - 1.8e-07 31.1 0.2 3.5e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EEQ33168.1 - 7.9e-07 29.6 0.1 1.9e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase APH PF01636.23 EEQ33169.1 - 9e-14 52.0 0.0 6.4e-13 49.2 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ33169.1 - 0.0097 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase tRNA-synt_1c PF00749.21 EEQ33170.1 - 3.5e-96 321.8 0.0 5.9e-96 321.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EEQ33170.1 - 4.5e-36 124.3 0.5 7e-36 123.7 0.5 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 EEQ33170.1 - 0.0033 17.4 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EEQ33170.1 - 0.0058 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ33170.1 - 0.024 14.8 0.0 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF1682 PF07946.14 EEQ33171.1 - 0.00066 19.0 12.0 0.00094 18.5 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) F-box PF00646.33 EEQ33172.1 - 2.2e-07 30.6 0.0 6.3e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EEQ33172.1 - 4.5e-06 26.5 0.1 1.1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 EEQ33172.1 - 0.052 13.7 4.8 2.5 8.4 0.2 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.7 EEQ33172.1 - 4.2 7.9 14.8 3.6 8.1 0.0 5.7 4 3 2 6 6 6 0 Leucine Rich repeats (2 copies) IDO PF01231.18 EEQ33173.1 - 9.3e-35 120.2 0.0 2.1e-34 119.0 0.0 1.4 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Glyco_hydro_16 PF00722.21 EEQ33174.1 - 1.8e-06 27.5 0.3 2.9e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CLTH PF10607.9 EEQ33175.1 - 4.9e-29 101.1 0.0 9.4e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EEQ33175.1 - 1.7e-08 34.6 0.0 3.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EEQ33175.1 - 0.00082 19.2 0.1 0.0031 17.4 0.1 2.1 2 0 0 2 2 2 1 LisH INO80_Ies4 PF08193.11 EEQ33176.1 - 1.2e-66 225.2 24.7 1.6e-66 224.8 24.7 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CPSF100_C PF13299.6 EEQ33176.1 - 1.9 8.6 4.5 1.4 9.1 0.6 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EEQ33176.1 - 8.6 5.0 4.9 5.6 5.6 0.3 2.0 2 0 0 2 2 2 0 Presenilin DnaJ PF00226.31 EEQ33177.1 - 8.3e-11 41.9 0.0 3e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 DnaJ domain RPA43_OB PF17875.1 EEQ33178.1 - 2.4e-41 141.2 0.1 2.4e-41 141.2 0.1 3.6 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I Pol_alpha_B_N PF08418.10 EEQ33178.1 - 1.3 8.9 26.0 0.057 13.4 1.5 3.2 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal Rab5ip PF07019.12 EEQ33179.1 - 1.2e-23 83.5 3.6 1.6e-23 83.1 3.6 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF5084 PF16894.5 EEQ33179.1 - 2.4 8.6 5.5 2.8 8.4 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5084) DSBA PF01323.20 EEQ33180.1 - 3.3e-31 108.6 0.0 3.9e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EEQ33180.1 - 0.0052 17.0 0.4 0.0078 16.4 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin MFS_1 PF07690.16 EEQ33181.1 - 1.1e-24 87.1 64.1 4.8e-23 81.6 17.6 3.7 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 EEQ33181.1 - 9.6e-09 34.2 13.9 1.6e-08 33.5 13.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sulfate_transp PF00916.20 EEQ33182.1 - 3.9e-103 345.2 22.4 5e-103 344.8 22.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EEQ33182.1 - 3.6e-05 23.4 0.0 6.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain MccV PF17508.2 EEQ33182.1 - 0.05 14.2 0.4 0.25 11.9 0.1 2.2 2 0 0 2 2 2 0 Microcin V bacteriocin MFS_MOT1 PF16983.5 EEQ33182.1 - 0.055 13.9 17.7 0.021 15.2 3.3 3.2 2 2 0 2 2 2 0 Molybdate transporter of MFS superfamily DnaJ_C PF01556.18 EEQ33184.1 - 1.4e-38 132.3 0.0 1.9e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEQ33184.1 - 1.2e-25 89.4 2.3 2e-25 88.7 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EEQ33184.1 - 1.1e-14 54.6 18.1 1.8e-14 53.9 18.1 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EEQ33184.1 - 0.45 10.6 9.0 0.85 9.7 1.7 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA URO-D PF01208.17 EEQ33185.1 - 6.7e-129 430.0 0.0 7.5e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Nod1 PF17114.5 EEQ33185.1 - 0.055 13.6 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 WD40 PF00400.32 EEQ33186.1 - 0.00045 21.0 1.1 1.1 10.2 0.2 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Ribosomal_L10 PF00466.20 EEQ33187.1 - 3.1e-24 85.0 0.1 7.3e-24 83.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EEQ33187.1 - 1.4e-20 73.0 0.0 2.9e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EEQ33187.1 - 1.1e-10 41.9 0.1 5.2e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein PDEase_I PF00233.19 EEQ33188.1 - 3.2e-45 154.7 0.0 1.4e-39 136.3 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Rdx PF10262.9 EEQ33189.1 - 2.6e-31 107.6 0.0 3.5e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.22 EEQ33190.1 - 5.7e-21 74.3 0.0 6.5e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 EEQ33191.1 - 2.9e-12 47.0 0.4 1.4e-10 41.6 0.0 3.1 2 0 0 2 2 2 1 PCI domain Pro_Al_protease PF02983.14 EEQ33191.1 - 0.058 13.5 0.0 0.35 11.0 0.0 2.4 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Phage_NinH PF06322.11 EEQ33192.1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Phage NinH protein Acetyltransf_1 PF00583.25 EEQ33193.1 - 1.5e-10 41.3 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ33193.1 - 8.9e-09 35.4 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ33193.1 - 2.1e-06 28.0 0.0 3.6e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ33193.1 - 7.8e-06 25.8 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EEQ33193.1 - 0.00053 20.1 0.1 0.00093 19.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EEQ33193.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 EEQ33194.1 - 6.1e-23 81.3 54.5 6.1e-17 61.6 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EEQ33195.1 - 1.9e-18 66.8 0.0 2.3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ33195.1 - 2e-14 53.5 0.0 2.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ33195.1 - 0.00019 20.9 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EEQ33195.1 - 0.00092 19.2 0.0 0.0017 18.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EEQ33195.1 - 0.035 13.7 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family RNA_pol_Rpb6 PF01192.22 EEQ33196.1 - 6.2e-17 61.2 0.1 8.8e-17 60.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 EEQ33197.1 - 8.7e-24 82.6 60.4 0.0001 22.5 0.6 11.7 11 1 1 12 12 12 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ33197.1 - 8.2e-16 57.4 59.2 0.0041 17.8 0.6 10.9 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEQ33197.1 - 3.8e-10 39.7 56.1 0.012 16.0 0.3 10.9 12 0 0 12 12 12 6 Zinc-finger double domain GAGA PF09237.11 EEQ33197.1 - 0.00016 21.4 0.4 0.00016 21.4 0.4 2.1 2 0 0 2 2 1 1 GAGA factor zf-C2H2_jaz PF12171.8 EEQ33197.1 - 0.00034 20.8 12.8 2.4 8.5 0.0 7.5 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EEQ33197.1 - 0.00063 20.3 34.0 0.67 10.6 0.1 8.3 6 2 3 9 9 9 3 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 EEQ33197.1 - 0.011 15.5 19.4 0.91 9.3 0.0 6.2 6 0 0 6 6 6 0 zinc-finger C2H2-type DUF5472 PF17566.2 EEQ33197.1 - 0.011 15.7 2.5 3.4 7.7 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5472) zf-C2H2_3rep PF18868.1 EEQ33197.1 - 0.019 15.7 18.3 1 10.0 0.3 5.7 3 3 2 6 6 6 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 EEQ33197.1 - 0.022 15.1 18.7 0.86 9.9 2.2 4.2 2 1 3 5 5 5 0 C2H2-type zinc ribbon zf-met PF12874.7 EEQ33197.1 - 3.1 8.3 13.1 6.5 7.3 0.1 6.2 7 0 0 7 7 7 0 Zinc-finger of C2H2 type CHORD PF04968.12 EEQ33197.1 - 5.4 7.8 18.1 1.6 9.5 0.8 4.6 4 1 1 5 5 4 0 CHORD zf-C2H2_9 PF16293.5 EEQ33197.1 - 6.1 6.8 6.4 8.6 6.3 0.4 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) COPIIcoated_ERV PF07970.12 EEQ33199.1 - 1.2e-79 267.2 0.1 2.6e-79 266.2 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EEQ33199.1 - 2.7e-29 101.4 0.0 6.1e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.13 EEQ33200.1 - 4.1e-11 42.4 0.4 9.4e-11 41.2 0.4 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 EEQ33200.1 - 3.7e-07 29.8 0.0 6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EEQ33200.1 - 4.9e-06 26.8 6.5 0.00068 20.0 0.4 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 EEQ33200.1 - 3.7e-05 24.3 0.0 9.5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 EEQ33200.1 - 0.00029 20.6 0.4 0.00065 19.4 0.4 1.6 1 0 0 1 1 1 1 Leucine rich repeat RRM_9 PF18444.1 EEQ33200.1 - 0.00029 20.6 0.0 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif Vps53_N PF04100.12 EEQ33201.1 - 7.1e-106 354.4 8.1 7.1e-106 354.4 8.1 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 EEQ33201.1 - 2.1e-07 30.6 5.9 2.1e-07 30.6 5.9 1.8 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EEQ33201.1 - 1.4e-05 25.1 0.1 6.4e-05 22.8 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.11 EEQ33201.1 - 0.00073 19.6 3.4 0.0013 18.9 1.7 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 GIT1_C PF12205.8 EEQ33201.1 - 0.37 10.9 7.4 0.71 10.0 0.7 2.8 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF1910 PF08928.10 EEQ33201.1 - 0.64 10.0 3.1 1.7 8.6 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) Sigma70_ner PF04546.13 EEQ33201.1 - 1.1 9.0 7.2 18 5.1 7.2 2.6 1 1 0 1 1 1 0 Sigma-70, non-essential region DUF1515 PF07439.11 EEQ33201.1 - 2.5 8.2 4.4 2.1 8.4 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) TRPM_tetra PF16519.5 EEQ33201.1 - 3.6 7.8 6.8 0.51 10.5 2.3 1.9 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DEAD PF00270.29 EEQ33202.1 - 8.2e-18 64.8 0.5 3.5e-17 62.7 0.2 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EEQ33202.1 - 5.2e-08 33.1 0.0 1.6e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ33202.1 - 3.6e-05 24.1 0.0 0.00028 21.2 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4332 PF14229.6 EEQ33202.1 - 0.09 13.0 0.4 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) DUF1524 PF07510.11 EEQ33205.1 - 8.6e-09 35.4 0.0 1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 EEQ33205.1 - 0.032 14.2 1.6 0.076 12.9 0.6 2.1 2 1 0 2 2 2 0 HNH endonuclease RPW8 PF05659.11 EEQ33206.1 - 0.051 13.3 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RrnaAD PF00398.20 EEQ33206.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pkinase PF00069.25 EEQ33208.1 - 7.8e-11 41.8 0.0 2e-10 40.5 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ33208.1 - 8.6e-06 25.2 0.0 8.6e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EEQ33208.1 - 0.063 13.2 0.1 0.3 11.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEQ33208.1 - 0.081 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EEQ33208.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 EEQ33209.1 - 4.6e-26 90.6 0.3 1.2e-06 29.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33209.1 - 2.1e-14 53.6 0.0 0.0091 16.3 0.0 5.1 3 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ33209.1 - 0.00055 19.9 0.2 0.1 12.4 0.0 2.9 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EEQ33209.1 - 0.0015 17.3 0.4 0.24 10.0 0.0 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EEQ33209.1 - 0.028 14.0 0.1 0.096 12.3 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain Ge1_WD40 PF16529.5 EEQ33209.1 - 0.039 12.9 1.9 3 6.7 0.1 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EEQ33209.1 - 0.069 12.2 0.1 4.4 6.2 0.0 2.3 1 1 0 2 2 2 0 Coatomer WD associated region FTHFS PF01268.19 EEQ33210.1 - 4e-249 827.4 0.0 8.2e-249 826.4 0.0 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EEQ33210.1 - 6.1e-66 220.7 1.3 6.1e-66 220.7 1.3 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EEQ33210.1 - 6.2e-35 120.0 0.1 1.5e-34 118.8 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EEQ33210.1 - 0.00086 18.3 0.6 0.0019 17.2 0.2 1.7 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family AdoHcyase_NAD PF00670.21 EEQ33210.1 - 0.14 12.2 0.8 3.4 7.7 0.8 2.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Iso_dh PF00180.20 EEQ33211.1 - 4.7e-56 190.4 0.0 2.5e-49 168.3 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase MBF1 PF08523.10 EEQ33212.1 - 3.2e-27 94.8 0.7 3.2e-27 94.8 0.7 1.7 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EEQ33212.1 - 9e-12 44.9 0.1 1.9e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EEQ33212.1 - 3e-07 30.7 0.2 7e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain MFS_1 PF07690.16 EEQ33213.1 - 0.013 14.5 35.6 0.19 10.6 34.8 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily SH3_1 PF00018.28 EEQ33214.1 - 1.8e-14 53.1 0.0 2.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ33214.1 - 9.8e-13 47.8 0.0 4.5e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EEQ33214.1 - 1.9e-07 30.6 0.0 3.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Glyco_tranf_2_3 PF13641.6 EEQ33215.1 - 5.4e-31 108.3 0.0 7e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EEQ33215.1 - 9.9e-08 32.0 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EEQ33215.1 - 2e-06 27.4 0.0 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EEQ33215.1 - 0.0037 17.2 1.8 0.0037 17.2 1.8 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 ATP12 PF07542.11 EEQ33218.1 - 2.1e-41 141.0 0.4 3.4e-41 140.3 0.4 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein UnbV_ASPIC PF07593.12 EEQ33218.1 - 0.044 13.7 0.1 0.19 11.7 0.1 2.0 1 1 0 1 1 1 0 ASPIC and UnbV Oxysterol_BP PF01237.18 EEQ33219.1 - 4.8e-136 453.5 0.0 1.2e-135 452.1 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 EEQ33219.1 - 1.3e-16 60.4 0.1 3.9e-10 39.8 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ33219.1 - 4.1e-16 59.3 0.0 1.2e-07 32.2 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EEQ33219.1 - 1.2e-12 47.6 0.0 0.0005 20.4 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EEQ33219.1 - 2.2e-11 42.9 0.0 0.00083 19.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat PH PF00169.29 EEQ33219.1 - 9.7e-11 42.1 0.3 2.5e-10 40.8 0.3 1.8 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EEQ33219.1 - 8.6e-09 35.8 0.0 0.00043 20.8 0.0 3.6 2 1 0 3 3 3 2 Ankyrin repeats (many copies) PH_8 PF15409.6 EEQ33219.1 - 5.6e-07 29.8 0.8 1.4e-06 28.5 0.8 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EEQ33219.1 - 1.5e-05 25.3 1.7 5.1e-05 23.6 1.7 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain LLC1 PF14945.6 EEQ33219.1 - 0.0032 18.0 0.3 0.0032 18.0 0.3 2.4 3 0 0 3 3 3 1 Normal lung function maintenance, Low in Lung Cancer 1 protein zf-Mss51 PF13824.6 EEQ33220.1 - 1.6e-28 98.5 6.5 4.7e-28 97.0 6.5 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EEQ33220.1 - 0.0059 16.7 2.5 0.0059 16.7 2.5 2.0 2 0 0 2 2 2 1 MYND finger ADH_zinc_N PF00107.26 EEQ33221.1 - 1.2e-28 99.7 0.6 1.8e-28 99.1 0.6 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ33221.1 - 2.2e-10 41.7 0.0 4.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ33221.1 - 2.3e-06 27.5 0.0 8.8e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EEQ33221.1 - 0.014 15.6 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ADH_N_2 PF16884.5 EEQ33221.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase adh_short PF00106.25 EEQ33221.1 - 0.052 13.0 0.3 0.072 12.5 0.3 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Pep_deformylase PF01327.21 EEQ33221.1 - 0.24 11.0 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase Clr5 PF14420.6 EEQ33222.1 - 3.6e-06 27.1 0.3 6.1e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 Clr5 domain DIM1 PF02966.16 EEQ33224.1 - 0.13 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 SNF2_N PF00176.23 EEQ33226.1 - 4.6e-63 213.0 1.0 7.7e-63 212.3 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ33226.1 - 1.1e-19 70.9 0.0 4.1e-19 69.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 EEQ33226.1 - 9.7e-10 38.6 8.1 4.1e-09 36.6 8.1 2.2 1 0 0 1 1 1 1 HSA ResIII PF04851.15 EEQ33226.1 - 5.1e-09 36.4 0.0 1.9e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEQ33226.1 - 6.4e-05 22.8 0.1 0.00087 19.1 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase MSA-2c PF12238.8 EEQ33226.1 - 0.064 13.2 2.8 0.2 11.7 2.8 1.8 1 0 0 1 1 1 0 Merozoite surface antigen 2c NDUF_B8 PF05821.11 EEQ33227.1 - 1.8e-05 24.7 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.9 EEQ33228.1 - 5e-19 68.9 0.2 3.4e-16 59.8 0.2 2.7 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EEQ33228.1 - 1.8e-13 50.6 0.0 4.9e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain Ribonuc_L-PSP PF01042.21 EEQ33229.1 - 8.7e-41 138.7 0.0 9.6e-41 138.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_10 PF13460.6 EEQ33230.1 - 3.5e-10 40.1 0.0 6.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ33230.1 - 4.8e-10 39.4 0.0 5.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EEQ33230.1 - 0.0001 22.6 0.1 0.00016 21.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EEQ33230.1 - 0.0002 20.9 0.0 0.0047 16.4 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EEQ33230.1 - 0.0028 17.7 0.3 0.0072 16.4 0.2 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EEQ33230.1 - 0.004 17.4 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Macro_2 PF14519.6 EEQ33230.1 - 0.028 13.8 0.4 0.67 9.2 0.1 2.2 2 0 0 2 2 2 0 Macro-like domain NAD_binding_4 PF07993.12 EEQ33230.1 - 0.042 13.0 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein CoA_binding_3 PF13727.6 EEQ33230.1 - 0.07 13.1 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 CoA-binding domain PglD_N PF17836.1 EEQ33230.1 - 0.081 13.6 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Lumazine_bd_2 PF12893.7 EEQ33231.1 - 3.6e-28 98.6 0.0 4.1e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Putative lumazine-binding Catalase PF00199.19 EEQ33232.1 - 1e-137 459.3 0.0 1.4e-137 458.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EEQ33232.1 - 7.5e-06 26.1 0.1 2e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive adh_short_C2 PF13561.6 EEQ33233.1 - 1.3e-43 149.2 0.1 1.7e-43 148.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ33233.1 - 5e-41 140.3 0.1 6.6e-41 139.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ33233.1 - 5.4e-13 49.2 0.4 9.6e-13 48.4 0.4 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ33233.1 - 6.7e-06 25.7 0.0 2.4e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EEQ33233.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EEQ33233.1 - 0.011 15.9 0.1 0.044 14.0 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF4332 PF14229.6 EEQ33233.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Delta_lysin PF05372.11 EEQ33233.1 - 0.069 12.5 1.3 0.17 11.2 0.1 2.3 3 0 0 3 3 3 0 Delta lysin family GDP_Man_Dehyd PF16363.5 EEQ33233.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_33 PF10017.9 EEQ33234.1 - 3.3e-81 272.8 0.0 3.9e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF4363 PF14276.6 EEQ33234.1 - 0.035 14.2 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) FAD_binding_4 PF01565.23 EEQ33235.1 - 1.4e-20 73.5 1.0 2.7e-20 72.5 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EEQ33235.1 - 4.2e-11 42.8 0.2 8.8e-11 41.7 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Trp_DMAT PF11991.8 EEQ33236.1 - 1.6e-110 370.0 0.0 2e-110 369.7 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase HD PF01966.22 EEQ33239.1 - 0.033 14.4 0.0 0.063 13.5 0.0 1.5 1 1 0 1 1 1 0 HD domain Pribosyltran PF00156.27 EEQ33241.1 - 1e-15 57.6 0.0 1.7e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EEQ33241.1 - 0.0081 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.20 EEQ33242.1 - 1.1e-114 383.8 0.0 1.7e-114 383.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DNA_pol_B_exo2 PF10108.9 EEQ33242.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB WD40 PF00400.32 EEQ33244.1 - 1.5e-30 104.7 13.6 1.4e-05 25.8 0.1 7.4 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33244.1 - 4.4e-10 39.7 0.0 0.02 15.2 0.0 4.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ33244.1 - 0.078 11.6 0.7 2.3 6.8 0.4 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EEQ33244.1 - 0.36 9.5 3.2 3.3 6.4 0.8 2.2 1 1 1 2 2 2 0 Nup133 N terminal like TRAPP PF04051.16 EEQ33245.1 - 1.2e-35 122.4 0.0 1.5e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 EEQ33245.1 - 0.0043 16.0 0.0 0.0048 15.8 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A LisH PF08513.11 EEQ33247.1 - 5.9e-05 22.9 0.1 0.00011 22.0 0.1 1.5 1 0 0 1 1 1 1 LisH TFB6 PF17110.5 EEQ33250.1 - 2.4e-31 108.8 11.0 7e-31 107.3 6.6 3.0 2 1 0 2 2 2 1 Subunit 11 of the general transcription factor TFIIH RRM_Rrp7 PF17799.1 EEQ33250.1 - 1.8e-26 92.9 0.0 3.2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 EEQ33250.1 - 3.1e-26 91.8 10.6 3.1e-26 91.8 10.6 2.3 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 EEQ33250.1 - 0.12 12.2 0.0 5.7 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad51 PF08423.11 EEQ33251.1 - 5.4e-114 379.7 0.0 6.8e-114 379.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EEQ33251.1 - 1.4e-14 54.2 0.1 1.9e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EEQ33251.1 - 9.6e-08 31.6 0.0 1.9e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 EEQ33251.1 - 2.1e-05 25.0 2.6 2.2e-05 25.0 0.8 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain Phage_HK97_TLTM PF06120.11 EEQ33251.1 - 0.0081 15.4 0.0 3 7.0 0.0 2.2 2 0 0 2 2 2 2 Tail length tape measure protein DnaB_C PF03796.15 EEQ33251.1 - 0.066 12.5 0.1 0.4 10.0 0.1 2.1 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 EEQ33251.1 - 0.089 12.5 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain DnaB_bind PF10410.9 EEQ33251.1 - 0.11 12.7 0.0 2.5 8.3 0.0 2.5 1 1 0 1 1 1 0 DnaB-helicase binding domain of primase FlgM PF04316.13 EEQ33251.1 - 0.11 12.9 0.9 20 5.6 0.1 3.5 4 0 0 4 4 4 0 Anti-sigma-28 factor, FlgM PAXNEB PF05625.11 EEQ33251.1 - 0.16 11.1 0.0 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 PAXNEB protein zf-CCHC PF00098.23 EEQ33252.1 - 7.2e-33 111.2 29.9 1.7e-07 31.0 0.9 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 EEQ33252.1 - 3.6e-06 26.8 17.3 0.028 14.4 0.4 4.2 3 1 1 4 4 4 4 Zinc knuckle zf-CCHC_5 PF14787.6 EEQ33252.1 - 1.9e-05 24.3 22.7 0.014 15.1 0.9 4.8 3 1 2 5 5 5 3 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EEQ33252.1 - 2e-05 24.2 21.3 0.14 11.9 0.5 5.0 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 EEQ33252.1 - 0.042 13.7 2.2 0.042 13.7 2.2 5.1 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_6 PF15288.6 EEQ33252.1 - 4.2 7.3 23.0 0.49 10.3 1.4 4.4 5 0 0 5 5 5 0 Zinc knuckle DUF753 PF05444.12 EEQ33252.1 - 6.4 6.8 14.6 31 4.5 3.8 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF753) UDPGP PF01704.18 EEQ33253.1 - 9.7e-57 192.5 0.0 1.3e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EEQ33253.1 - 0.028 14.8 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fer4_20 PF14691.6 EEQ33253.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pro_isomerase PF00160.21 EEQ33254.1 - 2e-31 109.4 0.0 3e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EEQ33254.1 - 1.4e-15 56.8 0.5 3.2e-15 55.7 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ33254.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 EEQ33255.1 - 1.2e-08 35.0 6.9 2.8e-08 33.7 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.19 EEQ33256.1 - 1.2e-32 111.6 0.1 2.1e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.9 EEQ33257.1 - 1.3e-19 70.6 0.0 2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EEQ33257.1 - 5.8e-05 22.6 0.0 8.5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EEQ33257.1 - 8.8e-05 23.1 0.0 0.00018 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEQ33257.1 - 0.00091 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EEQ33257.1 - 0.0034 17.2 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EEQ33257.1 - 0.005 16.6 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PCMT PF01135.19 EEQ33257.1 - 0.0079 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EEQ33257.1 - 0.028 15.2 0.0 0.053 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EEQ33257.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_11 PF08241.12 EEQ33257.1 - 0.04 14.6 0.0 0.07 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EEQ33257.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Pro-kuma_activ PF09286.11 EEQ33258.1 - 1e-37 129.6 0.1 2.8e-37 128.2 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EEQ33258.1 - 6.7e-08 32.1 0.0 3.7e-07 29.7 0.0 2.1 1 1 1 2 2 2 1 Subtilase family DUF2306 PF10067.9 EEQ33259.1 - 3.7e-11 43.5 11.3 3.7e-11 43.5 11.3 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Glyco_tran_28_C PF04101.16 EEQ33259.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain CSN8_PSD8_EIF3K PF10075.9 EEQ33261.1 - 1.4e-20 73.8 0.0 2.9e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EEQ33261.1 - 0.0064 15.9 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family ANAPC4_WD40 PF12894.7 EEQ33262.1 - 0.0098 16.2 0.0 0.28 11.5 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ33262.1 - 0.05 14.5 0.1 0.75 10.8 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Vps51 PF08700.11 EEQ33263.1 - 1.3e-24 86.1 0.0 2.1e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EEQ33263.1 - 0.0016 18.6 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 EEQ33263.1 - 0.011 14.4 0.1 0.017 13.9 0.1 1.1 1 0 0 1 1 1 0 Dor1-like family RMI1_N PF08585.12 EEQ33264.1 - 2.5e-63 213.8 0.0 2.8e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_17 PF13431.6 EEQ33265.1 - 9.7e-23 78.9 10.1 0.064 13.7 0.0 12.0 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ33265.1 - 3e-22 79.0 36.3 5.5e-05 23.7 0.8 12.8 11 3 2 14 14 13 7 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ33265.1 - 1.2e-21 75.0 57.8 0.01 15.9 0.3 16.2 18 0 0 18 18 16 8 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ33265.1 - 3.3e-21 75.6 30.1 1.8e-09 38.0 0.9 11.0 9 2 2 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ33265.1 - 1.7e-19 68.8 44.6 0.016 15.0 0.2 13.7 16 0 0 16 16 13 7 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ33265.1 - 2.1e-16 59.2 32.0 0.016 15.9 0.0 15.5 13 4 4 17 17 16 4 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ33265.1 - 6.6e-16 57.1 40.1 0.021 15.0 0.5 13.3 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ33265.1 - 2.9e-15 55.6 28.2 0.00036 20.2 0.0 10.6 10 1 1 11 11 11 4 TPR repeat TPR_12 PF13424.6 EEQ33265.1 - 1.2e-11 44.7 48.3 1.7e-05 25.0 1.5 13.4 10 5 4 14 14 14 4 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ33265.1 - 2.7e-05 24.5 31.2 0.2 12.4 0.2 12.7 15 0 0 15 15 12 2 Tetratricopeptide repeat TPR_22 PF18833.1 EEQ33265.1 - 0.00097 19.2 0.0 0.0028 17.7 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ33265.1 - 0.0023 17.8 0.0 0.0023 17.8 0.0 10.2 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ33265.1 - 0.0024 17.7 22.9 0.032 14.1 0.1 8.2 9 0 0 9 9 8 1 Tetratricopeptide repeat ChAPs PF09295.10 EEQ33265.1 - 0.012 14.7 2.9 14 4.5 0.1 4.5 4 1 1 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 EEQ33265.1 - 0.017 14.9 4.5 0.41 10.3 0.2 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.6 EEQ33265.1 - 0.019 14.4 0.4 0.019 14.4 0.4 4.4 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP PknG_TPR PF16918.5 EEQ33265.1 - 0.022 13.5 1.2 0.18 10.5 0.0 2.9 3 0 0 3 3 3 0 Protein kinase G tetratricopeptide repeat TPR_9 PF13371.6 EEQ33265.1 - 0.072 13.3 15.4 13 6.0 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat BTAD PF03704.17 EEQ33265.1 - 1.9 8.9 17.9 0.45 11.0 0.2 5.3 5 1 1 6 6 4 0 Bacterial transcriptional activator domain FAT PF02259.23 EEQ33265.1 - 3.9 6.6 12.3 13 4.8 0.0 4.5 5 0 0 5 5 5 0 FAT domain ANAPC5 PF12862.7 EEQ33265.1 - 6.4 6.9 15.8 1.6 8.9 0.1 6.2 6 2 1 7 7 7 0 Anaphase-promoting complex subunit 5 Glyco_hydro_5_C PF18564.1 EEQ33266.1 - 1e-22 80.4 0.0 2.5e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EEQ33266.1 - 5e-08 32.7 4.3 2e-06 27.5 1.3 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Xpo1 PF08389.12 EEQ33267.1 - 1e-12 48.3 6.0 3e-10 40.4 1.9 4.0 3 1 0 3 3 3 1 Exportin 1-like protein Drf_GBD PF06371.13 EEQ33267.1 - 0.0056 16.3 0.2 0.012 15.2 0.2 1.5 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain IBN_N PF03810.19 EEQ33267.1 - 0.033 14.1 0.3 0.36 10.8 0.0 2.7 2 0 0 2 2 2 0 Importin-beta N-terminal domain GRIM-19 PF06212.12 EEQ33268.1 - 3e-22 79.0 0.2 1.1e-21 77.1 0.2 1.7 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 EEQ33269.1 - 2.2e-24 86.2 0.1 7.9e-23 81.2 0.1 2.2 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VID27 PF08553.10 EEQ33270.1 - 6.5e-194 643.8 0.0 8.9e-194 643.4 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EEQ33270.1 - 1.2e-74 249.9 0.1 1.2e-74 249.9 0.1 3.1 2 1 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 EEQ33270.1 - 2.5e-47 159.7 1.4 1.1e-46 157.6 0.6 2.3 2 0 0 2 2 2 1 VID27 PH-like domain PTPRCAP PF15713.5 EEQ33270.1 - 1.8 8.9 14.1 5.2 7.4 14.1 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Usp PF00582.26 EEQ33270.1 - 1.9 9.0 6.0 44 4.6 0.0 2.7 2 0 0 2 2 2 0 Universal stress protein family Nop14 PF04147.12 EEQ33270.1 - 5 5.2 16.0 7.5 4.6 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EEQ33270.1 - 5.7 5.1 11.5 8.6 4.5 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EEQ33270.1 - 7.4 4.5 17.9 11 3.9 17.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi TLD PF07534.16 EEQ33271.1 - 2.6e-21 76.3 0.0 2.3e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 TLD Adaptin_N PF01602.20 EEQ33272.1 - 6.7e-117 391.2 8.1 6.3e-98 328.6 9.1 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EEQ33272.1 - 3.4e-65 219.0 3.8 1.1e-61 207.6 0.3 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ33272.1 - 5.6e-15 55.5 4.5 4.3e-06 27.0 0.0 5.5 4 1 1 6 6 6 3 HEAT repeats HEAT PF02985.22 EEQ33272.1 - 9.6e-12 44.1 0.1 0.023 14.9 0.0 5.4 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 EEQ33272.1 - 0.00043 20.7 4.5 0.74 10.4 0.0 6.1 5 1 1 6 6 6 1 HEAT-like repeat CLASP_N PF12348.8 EEQ33272.1 - 0.0093 15.6 0.7 1.6 8.3 0.0 3.8 2 1 2 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 EEQ33272.1 - 0.018 15.2 0.0 4.6 7.5 0.0 3.7 2 2 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Ribosomal_60s PF00428.19 EEQ33272.1 - 3.2 8.4 9.8 6.8 7.4 5.5 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein DEK_C PF08766.11 EEQ33273.1 - 9.7e-05 22.2 0.4 0.00025 20.9 0.4 1.6 1 0 0 1 1 1 1 DEK C terminal domain HATPase_c_2 PF13581.6 EEQ33273.1 - 0.079 12.9 0.5 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Evr1_Alr PF04777.13 EEQ33274.1 - 2.9e-29 101.5 2.4 2.9e-29 101.5 2.4 1.7 2 1 0 2 2 2 1 Erv1 / Alr family Sporozoite_P67 PF05642.11 EEQ33274.1 - 0.43 8.6 4.2 0.45 8.5 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Coatomer_WDAD PF04053.14 EEQ33275.1 - 2.6e-141 471.7 0.1 3.9e-141 471.1 0.1 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EEQ33275.1 - 4.8e-109 364.8 0.0 7e-109 364.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EEQ33275.1 - 2.8e-35 119.7 20.0 1.8e-07 31.8 0.3 8.2 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33275.1 - 9e-09 35.5 0.1 0.022 15.0 0.0 5.8 4 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EEQ33275.1 - 0.0041 17.0 0.2 0.35 10.7 0.0 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Nup160 PF11715.8 EEQ33275.1 - 0.02 13.5 6.0 1.5 7.3 0.4 3.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Phytase-like PF13449.6 EEQ33277.1 - 2.6e-40 139.2 0.1 3.5e-40 138.7 0.1 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase MMPL PF03176.15 EEQ33277.1 - 0.27 10.1 0.0 0.37 9.7 0.0 1.2 1 0 0 1 1 1 0 MMPL family Clr5 PF14420.6 EEQ33279.1 - 3.4e-20 72.0 1.2 3.4e-20 72.0 1.2 2.4 3 0 0 3 3 3 1 Clr5 domain Het-C PF07217.11 EEQ33280.1 - 2e-245 815.6 0.0 2.5e-245 815.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C TraT PF05818.12 EEQ33280.1 - 2.3 7.9 5.2 7.7 6.1 5.2 1.8 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2828 PF11443.8 EEQ33281.1 - 8.1e-233 774.1 0.1 9.6e-233 773.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) FAD-oxidase_C PF02913.19 EEQ33282.1 - 3.6e-60 203.7 0.1 6.3e-60 202.9 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EEQ33282.1 - 3.9e-35 120.6 0.0 6.3e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Mannosidase_ig PF17786.1 EEQ33283.1 - 7.5e-16 58.5 0.3 8.8e-15 55.1 0.0 2.4 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EEQ33283.1 - 1.6e-09 38.4 0.0 3.4e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EEQ33283.1 - 2.5e-07 30.7 0.0 6.2e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EEQ33283.1 - 0.00015 21.0 0.6 0.00097 18.3 0.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 EEQ33283.1 - 0.0036 17.0 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain ADH_N PF08240.12 EEQ33284.1 - 3.2e-32 110.6 2.1 5.7e-32 109.8 0.3 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ33284.1 - 7.9e-24 84.1 0.1 1.5e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EEQ33284.1 - 8.4e-08 32.0 0.1 1.6e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EEQ33284.1 - 0.0002 22.4 0.0 0.00048 21.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EEQ33284.1 - 0.0083 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EEQ33284.1 - 0.02 14.2 0.2 0.035 13.4 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FtsJ PF01728.19 EEQ33284.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase AdoHcyase_NAD PF00670.21 EEQ33284.1 - 0.094 12.8 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_25 PF13649.6 EEQ33284.1 - 0.12 13.1 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EEQ33284.1 - 0.14 11.9 0.1 0.95 9.2 0.0 2.0 2 0 0 2 2 2 0 Met-10+ like-protein Ras PF00071.22 EEQ33285.1 - 1.2e-41 142.0 0.0 1.6e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ33285.1 - 6.6e-29 100.6 0.0 9.2e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ33285.1 - 5.6e-12 45.5 0.0 2.9e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ33285.1 - 7.1e-05 22.4 0.0 0.00035 20.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEQ33285.1 - 0.00011 22.2 0.0 0.00018 21.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEQ33285.1 - 0.00019 20.9 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EEQ33285.1 - 0.0018 18.2 0.0 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 EEQ33285.1 - 0.02 14.7 0.0 0.91 9.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EEQ33285.1 - 0.022 15.3 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EEQ33285.1 - 0.024 14.8 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EEQ33285.1 - 0.034 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 EEQ33285.1 - 0.037 13.9 0.0 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 EEQ33285.1 - 0.067 13.6 0.3 0.42 11.0 0.1 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EEQ33285.1 - 0.1 12.9 0.0 0.21 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EEQ33285.1 - 0.17 11.7 0.0 0.46 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EEQ33285.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region bZIP_1 PF00170.21 EEQ33286.1 - 5.8e-06 26.3 7.9 1.3e-05 25.2 7.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor LPP PF04728.13 EEQ33286.1 - 0.018 15.4 0.2 0.036 14.5 0.2 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper SF-assemblin PF06705.11 EEQ33286.1 - 0.077 12.3 1.4 0.11 11.8 1.4 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin bZIP_2 PF07716.15 EEQ33286.1 - 1.5 9.0 8.5 2.8 8.1 8.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper F-box-like PF12937.7 EEQ33288.1 - 0.018 15.0 0.7 0.069 13.1 0.7 2.1 2 1 0 2 2 2 0 F-box-like FlgM PF04316.13 EEQ33288.1 - 0.21 12.0 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM AIM24 PF01987.17 EEQ33289.1 - 1.9e-55 187.8 0.6 2.3e-55 187.6 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.17 EEQ33290.1 - 6.8e-41 138.8 0.1 1.2e-40 138.1 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-HYPF PF07503.12 EEQ33290.1 - 0.36 10.7 2.8 12 5.8 0.0 2.7 3 0 0 3 3 3 0 HypF finger DUF2894 PF11445.8 EEQ33290.1 - 0.89 10.0 4.3 21 5.5 4.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) RR_TM4-6 PF06459.12 EEQ33290.1 - 1 9.1 12.2 1.4 8.7 12.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Arc_trans_TRASH PF08394.10 EEQ33290.1 - 1.2 9.5 7.4 1.1 9.6 0.3 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain bZIP_1 PF00170.21 EEQ33295.1 - 8.3e-05 22.6 12.9 0.0053 16.8 12.9 2.3 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EEQ33295.1 - 0.0035 17.4 14.5 0.0035 17.4 14.5 1.9 1 1 1 2 2 2 1 Basic region leucine zipper SOUL PF04832.12 EEQ33295.1 - 0.063 13.4 0.1 0.094 12.9 0.1 1.3 1 0 0 1 1 1 0 SOUL heme-binding protein Pox_A_type_inc PF04508.12 EEQ33295.1 - 0.07 13.0 1.0 0.07 13.0 1.0 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Codanin-1_C PF15296.6 EEQ33295.1 - 3.2 7.9 6.7 12 6.1 6.8 1.9 1 1 0 1 1 1 0 Codanin-1 C-terminus RRM_1 PF00076.22 EEQ33296.1 - 1e-23 82.9 0.0 1.4e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ33296.1 - 0.0004 20.4 0.0 0.00072 19.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 EEQ33296.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif ChaC PF04752.12 EEQ33297.1 - 5.9e-32 111.2 0.0 8.3e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.32 EEQ33298.1 - 6.5e-20 69.1 5.9 1.1e-06 27.8 0.2 4.7 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EEQ33298.1 - 3.4e-17 60.8 4.9 0.0011 18.7 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EEQ33298.1 - 1.5e-16 60.0 7.8 7.3e-09 35.3 0.1 4.6 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_7 PF13499.6 EEQ33298.1 - 1.4e-15 57.5 5.5 2.5e-07 31.1 0.0 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EEQ33298.1 - 1.7e-13 49.4 7.6 9.4e-05 21.7 0.4 4.6 4 1 0 4 4 4 3 EF hand EF-hand_14 PF17959.1 EEQ33298.1 - 0.15 12.4 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain G6PD_C PF02781.16 EEQ33299.1 - 1.2e-114 382.4 0.0 1.8e-114 381.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EEQ33299.1 - 4.3e-61 206.6 0.0 1e-60 205.4 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.16 EEQ33300.1 - 3e-30 105.3 54.8 1.1e-28 100.2 54.2 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ33300.1 - 3.3e-09 35.7 15.8 7.4e-07 28.0 8.3 2.7 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ33300.1 - 3.4e-08 32.8 8.1 3.4e-08 32.8 8.1 3.7 2 2 0 3 3 3 1 Sugar (and other) transporter CBS PF00571.28 EEQ33301.1 - 0.00013 22.3 0.1 0.7 10.4 0.1 3.3 1 1 1 2 2 2 2 CBS domain ADH_zinc_N_2 PF13602.6 EEQ33302.1 - 0.0001 23.3 0.0 0.018 16.1 0.0 2.0 1 1 1 2 2 2 2 Zinc-binding dehydrogenase SnoaL_2 PF12680.7 EEQ33303.1 - 0.066 13.9 0.0 0.18 12.5 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Mito_carr PF00153.27 EEQ33304.1 - 2.8e-49 165.0 7.7 4e-20 71.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 EEQ33305.1 - 1e-29 102.1 24.0 1.1e-07 32.4 0.2 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33305.1 - 1.5e-11 44.4 4.7 0.029 14.7 0.1 5.3 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EEQ33305.1 - 0.12 11.4 0.2 0.21 10.6 0.2 1.3 1 0 0 1 1 1 0 Coatomer WD associated region ICE2 PF08426.10 EEQ33307.1 - 1.7e-132 442.4 15.2 2e-132 442.1 15.2 1.0 1 0 0 1 1 1 1 ICE2 Endosulfine PF04667.17 EEQ33308.1 - 2.4e-14 53.2 0.4 6.2e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.13 EEQ33309.1 - 2e-81 272.4 0.0 2.3e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 EEQ33310.1 - 3.9e-114 382.3 0.0 5.2e-114 381.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Pro_isomerase PF00160.21 EEQ33311.1 - 2.4e-46 157.9 0.2 3e-46 157.6 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD COesterase PF00135.28 EEQ33312.1 - 1.1e-97 328.1 0.0 1.5e-97 327.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EEQ33312.1 - 0.00014 21.8 0.0 0.00031 20.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ33312.1 - 0.006 16.1 0.0 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Fungal_trans_2 PF11951.8 EEQ33313.1 - 3.3e-06 26.2 0.3 2.6e-05 23.2 0.3 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.29 EEQ33314.1 - 7.7e-48 162.6 0.0 3e-47 160.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ33314.1 - 3.4e-32 111.1 0.0 7.7e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ33314.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 EEQ33314.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EEQ33314.1 - 0.23 10.7 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DDHD PF02862.17 EEQ33315.1 - 0.82 9.8 6.5 0.92 9.6 1.1 2.8 2 0 0 2 2 2 0 DDHD domain INSIG PF07281.12 EEQ33316.1 - 1.8e-61 207.5 7.3 4.1e-61 206.3 7.3 1.6 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Clathrin PF00637.20 EEQ33317.1 - 6.6e-196 642.1 33.7 3.3e-33 114.6 1.4 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EEQ33317.1 - 5.9e-35 117.9 6.0 3.8e-06 26.9 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EEQ33317.1 - 9.8e-31 105.5 1.4 2.8e-30 104.0 0.2 2.5 2 0 0 2 2 2 1 Clathrin-H-link TPR_14 PF13428.6 EEQ33317.1 - 7.5e-06 26.3 6.3 0.32 11.9 0.2 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat Clathrin-link PF09268.10 EEQ33317.1 - 0.0012 18.2 0.1 0.0026 17.1 0.1 1.6 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_8 PF13181.6 EEQ33317.1 - 0.024 14.8 3.1 4.2 7.8 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat VapB_antitoxin PF09957.9 EEQ33317.1 - 0.19 11.6 1.6 0.44 10.5 0.0 2.5 3 0 0 3 3 3 0 Bacterial antitoxin of type II TA system, VapB DUF1400 PF07176.11 EEQ33317.1 - 0.23 11.7 7.1 10 6.4 0.0 5.1 4 2 2 6 6 6 0 Alpha/beta hydrolase of unknown function (DUF1400) TPR_19 PF14559.6 EEQ33317.1 - 0.38 11.3 5.7 52 4.5 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EEQ33317.1 - 1 8.3 8.5 2 7.4 0.3 3.3 4 0 0 4 4 4 0 Coatomer WD associated region TPR_7 PF13176.6 EEQ33317.1 - 1.1 9.5 8.6 70 3.8 0.1 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ33317.1 - 1.3 8.9 4.1 33 4.5 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 EEQ33318.1 - 2.7e-80 268.9 0.1 4.6e-80 268.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EEQ33318.1 - 9.5e-70 234.4 0.0 1.6e-69 233.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EEQ33318.1 - 9.9e-40 135.5 0.1 2.1e-39 134.5 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EEQ33318.1 - 1.1e-31 109.1 0.0 3.8e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EEQ33318.1 - 2.6e-25 89.5 0.0 5.8e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EEQ33318.1 - 4.2e-17 61.7 4.6 4.6e-17 61.6 2.9 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EEQ33318.1 - 3.1e-09 36.5 1.4 0.0001 22.1 0.1 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EEQ33318.1 - 4.5e-09 36.1 0.0 8.8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EEQ33318.1 - 2e-06 27.5 0.0 4.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EEQ33318.1 - 0.00021 21.4 0.0 0.00056 20.0 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 EEQ33318.1 - 0.00024 20.8 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 EEQ33318.1 - 0.0014 17.8 0.2 0.084 12.1 0.1 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EEQ33318.1 - 0.013 16.1 0.1 7.6 7.3 0.1 3.3 3 0 0 3 3 3 0 HlyD family secretion protein DUF2118 PF09891.9 EEQ33318.1 - 0.041 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATP-grasp_4 PF13535.6 EEQ33318.1 - 0.059 13.0 0.0 0.71 9.5 0.0 2.4 2 1 0 2 2 2 0 ATP-grasp domain DLIC PF05783.11 EEQ33319.1 - 0.27 10.0 3.6 0.33 9.7 3.6 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ribosomal_L5_C PF00673.21 EEQ33320.1 - 3.4e-22 78.4 0.0 5.1e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EEQ33320.1 - 2.1e-20 72.8 0.0 7.4e-20 71.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 EEQ33321.1 - 6.5e-19 67.4 0.0 8e-19 67.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_S3Ae PF01015.18 EEQ33321.1 - 0.088 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal S3Ae family MPC PF03650.13 EEQ33322.1 - 3.8e-28 97.8 0.0 2.2e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial pyruvate carriers OFeT_1 PF16955.5 EEQ33322.1 - 0.21 11.3 0.5 0.54 9.9 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron uptake permease, iron-lead transporter Aa_trans PF01490.18 EEQ33323.1 - 5.6e-87 292.1 34.4 6.7e-87 291.8 34.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SID-1_RNA_chan PF13965.6 EEQ33323.1 - 5.9 5.2 8.8 11 4.2 8.8 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AA_permease PF00324.21 EEQ33324.1 - 6.5e-50 170.1 32.9 9e-50 169.6 32.9 1.2 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EEQ33324.1 - 6.2e-22 78.2 0.1 9.1e-07 28.2 0.0 3.3 3 0 0 3 3 3 3 Solute carrier family 12 Na_trans_assoc PF06512.13 EEQ33324.1 - 0.12 12.6 1.3 0.21 11.9 1.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated GHMP_kinases_N PF00288.26 EEQ33325.1 - 8.1e-16 58.0 0.2 2.9e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEQ33325.1 - 2.7e-08 34.0 0.0 7.2e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EEQ33325.1 - 0.00042 19.8 0.0 0.0008 18.9 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.22 EEQ33326.1 - 1e-33 114.1 23.2 4.1e-09 35.9 1.4 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.6 EEQ33326.1 - 0.00011 22.7 3.1 0.0007 20.2 1.4 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ33326.1 - 0.021 15.6 2.5 0.04 14.7 0.9 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ33326.1 - 0.076 13.4 0.0 0.45 11.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPPII_N PF12583.8 EEQ33326.1 - 0.083 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal PALP PF00291.25 EEQ33327.1 - 1.8e-53 181.9 1.0 5.5e-52 177.0 0.2 2.3 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Sporozoite_P67 PF05642.11 EEQ33328.1 - 0.095 10.8 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 EEQ33328.1 - 0.6 9.8 5.3 0.8 9.4 4.1 1.7 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 EEQ33328.1 - 0.95 10.5 4.4 1 10.4 3.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RPA43_OB PF17875.1 EEQ33328.1 - 2.6 8.7 8.9 6.2 7.5 8.9 1.6 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I AP-5_subunit_s1 PF15001.6 EEQ33328.1 - 5.3 7.0 5.9 9.2 6.2 5.9 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Presenilin PF01080.17 EEQ33328.1 - 6.1 5.5 5.0 8.4 5.0 5.0 1.1 1 0 0 1 1 1 0 Presenilin tRNA-synt_1g PF09334.11 EEQ33329.1 - 2.9e-96 322.6 0.1 2.6e-95 319.5 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EEQ33329.1 - 2e-22 79.2 0.6 1.6e-11 43.2 0.0 3.6 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EEQ33329.1 - 8.7e-10 38.4 0.1 2.5e-05 23.8 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EEQ33329.1 - 0.0023 17.9 0.0 0.0059 16.6 0.0 1.6 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA NTF2 PF02136.20 EEQ33330.1 - 1e-09 39.0 0.3 5.8e-08 33.3 0.3 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EEQ33330.1 - 0.00017 21.6 0.1 0.00034 20.6 0.1 1.4 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 Ribosomal_L38e PF01781.18 EEQ33331.1 - 4.2e-32 110.0 1.7 4.9e-32 109.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Ish1 PF10281.9 EEQ33332.1 - 3.8e-05 23.9 0.1 8.8e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein Flagellar_put PF12611.8 EEQ33332.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative flagellar Acetyltransf_3 PF13302.7 EEQ33333.1 - 6e-27 95.0 0.0 1e-26 94.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EEQ33333.1 - 0.00023 20.9 1.1 0.73 9.5 0.3 3.2 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ33333.1 - 0.0007 19.5 0.2 0.021 14.8 0.0 2.2 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 EEQ33333.1 - 0.0053 16.9 0.1 0.02 15.0 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ33333.1 - 0.15 12.3 0.1 15 5.9 0.0 2.4 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family DNA_pol_E_B PF04042.16 EEQ33334.1 - 4e-45 153.8 0.0 1e-44 152.4 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EEQ33334.1 - 2.7e-37 127.8 0.0 4.1e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain NMO PF03060.15 EEQ33335.1 - 1.4e-53 182.4 0.2 1.8e-53 182.1 0.2 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EEQ33335.1 - 2.5e-06 26.7 0.5 2.3e-05 23.6 0.5 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EEQ33335.1 - 0.0026 16.8 2.9 0.004 16.2 2.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 EEQ33335.1 - 0.097 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Taxilin PF09728.9 EEQ33336.1 - 2.6e-82 276.4 46.6 3.1e-82 276.2 46.6 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein COG2 PF06148.11 EEQ33336.1 - 0.067 13.3 14.8 0.75 9.9 0.3 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_TATA_bd PF12325.8 EEQ33336.1 - 0.34 11.1 39.5 1.2 9.4 6.2 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 EEQ33336.1 - 0.55 9.5 32.7 1.3 8.3 3.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF812 PF05667.11 EEQ33336.1 - 0.67 8.8 32.7 1 8.2 32.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 EEQ33336.1 - 2 8.5 40.9 1.8 8.6 2.9 3.3 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.14 EEQ33336.1 - 2.1 8.7 35.7 0.039 14.3 4.6 3.3 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF4201 PF13870.6 EEQ33336.1 - 2.3 7.9 38.4 0.064 13.0 16.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) BRE1 PF08647.11 EEQ33336.1 - 2.5 8.2 36.6 2.2 8.4 8.7 3.8 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase zf-C4H2 PF10146.9 EEQ33336.1 - 4.2 7.6 24.5 0.25 11.6 8.7 2.9 2 1 1 3 3 3 0 Zinc finger-containing protein DUF3584 PF12128.8 EEQ33336.1 - 4.9 4.5 39.3 5.1 4.5 36.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Laminin_II PF06009.12 EEQ33336.1 - 6.4 6.8 23.3 0.33 11.0 3.6 3.2 1 1 1 3 3 3 0 Laminin Domain II UPF0242 PF06785.11 EEQ33336.1 - 7.2 6.7 43.5 1.5 8.9 15.3 3.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus M16C_assoc PF08367.11 EEQ33337.1 - 7.2e-73 244.8 0.5 1.2e-72 244.1 0.5 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EEQ33337.1 - 2.5e-22 79.8 0.0 4.4e-15 56.2 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EEQ33337.1 - 1.9e-10 40.9 0.4 1.9e-09 37.7 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Methyltransf_25 PF13649.6 EEQ33338.1 - 1.7e-16 60.7 0.1 3.2e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ33338.1 - 1.7e-15 57.5 0.1 2.7e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ33338.1 - 3.3e-13 49.7 0.0 4.4e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ33338.1 - 2.7e-12 47.3 0.0 4.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ33338.1 - 6e-11 42.5 0.0 7.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EEQ33338.1 - 1.7e-08 34.1 0.0 2.2e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EEQ33338.1 - 2.8e-07 29.8 0.0 4.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EEQ33338.1 - 3.7e-07 29.8 0.0 5.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EEQ33338.1 - 5.7e-07 29.1 0.0 8.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EEQ33338.1 - 2.5e-05 24.1 0.0 3.7e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 EEQ33338.1 - 4.1e-05 23.3 0.0 6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 EEQ33338.1 - 0.0002 20.5 0.0 0.0003 20.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 EEQ33338.1 - 0.002 18.3 0.0 0.0064 16.6 0.0 1.6 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EEQ33338.1 - 0.0034 17.4 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EEQ33338.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.13 EEQ33338.1 - 0.022 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EEQ33338.1 - 0.041 13.5 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 EEQ33338.1 - 0.091 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltr_RsmB-F PF01189.17 EEQ33338.1 - 0.14 11.8 0.0 1.6 8.4 0.0 2.0 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF202 PF02656.15 EEQ33339.1 - 4.8e-18 65.4 0.8 4.8e-18 65.4 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cation_efflux PF01545.21 EEQ33340.1 - 8.3e-55 185.6 4.0 1.4e-54 184.8 4.0 1.4 1 1 0 1 1 1 1 Cation efflux family Pkinase PF00069.25 EEQ33341.1 - 3.1e-23 82.5 0.0 6.3e-23 81.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ33341.1 - 1.5e-07 31.0 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ33341.1 - 0.033 13.0 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Metallophos PF00149.28 EEQ33342.1 - 1.6e-06 28.8 4.2 3e-06 27.9 4.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Tyrosinase PF00264.20 EEQ33343.1 - 1.1e-47 163.2 5.8 1.1e-47 163.2 5.8 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EEQ33343.1 - 4.4e-26 91.9 0.0 7.6e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Fungal_trans PF04082.18 EEQ33344.1 - 6.2e-15 55.0 2.2 4.9e-13 48.7 2.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ33344.1 - 2.4 8.4 10.8 5.4 7.2 10.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S8e PF01201.22 EEQ33345.1 - 8.3e-45 152.3 3.3 1.2e-44 151.8 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e RIBIOP_C PF04950.12 EEQ33345.1 - 0.15 11.4 5.5 0.34 10.3 5.5 1.6 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Ribosomal_L21p PF00829.21 EEQ33346.1 - 1.6e-09 38.0 0.0 2.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Atrophin-1 PF03154.15 EEQ33346.1 - 0.0035 15.7 8.3 0.0048 15.3 8.3 1.1 1 0 0 1 1 1 1 Atrophin-1 family CutA1 PF03091.15 EEQ33346.1 - 0.16 11.8 0.9 0.39 10.6 0.3 1.8 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein Pkinase PF00069.25 EEQ33347.1 - 1.4e-48 165.6 0.0 2.1e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ33347.1 - 4.5e-18 65.5 0.0 7.1e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EEQ33347.1 - 0.00021 20.9 0.2 0.00056 19.6 0.1 1.8 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 EEQ33347.1 - 0.00061 19.8 0.4 0.44 10.4 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EEQ33347.1 - 0.012 15.0 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ33347.1 - 0.053 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EEQ33347.1 - 0.14 10.9 0.3 0.48 9.1 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase DUF4648 PF15505.6 EEQ33347.1 - 0.66 10.9 5.8 2.1 9.2 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF4648) PWI PF01480.17 EEQ33348.1 - 2.5e-31 107.8 0.1 3.7e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 PWI domain FAA_hydrolase PF01557.18 EEQ33351.1 - 4.4e-53 180.2 0.0 5.4e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Nup54_57_C PF18570.1 EEQ33352.1 - 0.0065 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Snapin_Pallidin PF14712.6 EEQ33352.1 - 0.033 14.6 3.6 0.048 14.1 2.3 1.9 1 1 1 2 2 2 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 EEQ33352.1 - 0.056 13.5 1.5 0.12 12.4 1.5 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cortex-I_coil PF09304.10 EEQ33352.1 - 0.21 11.8 9.1 0.082 13.1 6.4 1.8 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF883 PF05957.13 EEQ33352.1 - 0.22 12.1 4.8 0.34 11.5 2.6 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DEAD PF00270.29 EEQ33353.1 - 7.5e-45 152.8 0.7 1.5e-44 151.9 0.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ33353.1 - 1.1e-31 109.5 0.2 4e-31 107.6 0.1 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ33353.1 - 6.5e-07 29.5 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EEQ33353.1 - 4.3e-05 23.3 0.1 8.4e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ33353.1 - 0.00033 21.0 0.2 0.003 17.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ33353.1 - 0.0048 17.2 0.6 0.029 14.7 0.6 2.2 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 EEQ33353.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 EEQ33353.1 - 0.076 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Helicase fragilysinNterm PF16376.5 EEQ33353.1 - 0.097 12.4 0.0 0.34 10.7 0.0 1.9 1 0 0 1 1 1 0 N-terminal domain of fragilysin Flavi_DEAD PF07652.14 EEQ33353.1 - 0.13 12.2 0.1 0.8 9.7 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Cupin_8 PF13621.6 EEQ33354.1 - 2.1e-16 60.4 0.0 1.8e-14 54.1 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EEQ33354.1 - 2.6e-09 37.5 0.4 2.8e-08 34.2 0.1 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase F-box-like PF12937.7 EEQ33354.1 - 0.00017 21.4 0.1 0.00038 20.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ33354.1 - 0.061 13.2 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain TFA2_Winged_2 PF18121.1 EEQ33354.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 Cupin_4 PF08007.12 EEQ33354.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Ctr PF04145.15 EEQ33355.1 - 5e-22 79.1 7.4 2.5e-21 76.8 7.4 1.8 1 1 0 1 1 1 1 Ctr copper transporter family NuA4 PF09340.10 EEQ33356.1 - 1.8e-27 95.0 0.2 3.5e-27 94.1 0.2 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Glyco_hydro_38N PF01074.22 EEQ33357.1 - 4e-87 292.3 0.8 8.2e-87 291.2 0.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EEQ33357.1 - 5.5e-55 186.7 0.4 4.7e-54 183.7 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EEQ33357.1 - 7.8e-26 90.1 0.0 1.5e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EEQ33357.1 - 8.5e-11 41.8 0.0 2.7e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain 7TMR-DISMED2 PF07696.11 EEQ33357.1 - 0.042 13.9 0.1 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 NUDIX PF00293.28 EEQ33359.1 - 1.8e-08 34.5 0.0 5.5e-08 32.9 0.0 1.9 1 1 1 2 2 2 1 NUDIX domain PHINT_rpt PF14882.6 EEQ33359.1 - 0.45 10.8 2.2 1 9.7 2.2 1.6 1 0 0 1 1 1 0 Phage-integrase repeat unit LETM1 PF07766.13 EEQ33360.1 - 1.3e-89 300.1 0.2 9.2e-88 294.1 0.2 2.4 1 1 0 1 1 1 1 LETM1-like protein SAP PF02037.27 EEQ33360.1 - 0.0032 17.2 0.1 0.55 10.0 0.0 3.3 3 0 0 3 3 3 1 SAP domain KIAA1430 PF13879.6 EEQ33360.1 - 6.4 7.6 8.6 3.9 8.3 1.1 3.1 3 0 0 3 3 3 0 KIAA1430 homologue DUF2838 PF10998.8 EEQ33361.1 - 2.6e-39 133.9 11.2 2.6e-39 133.9 11.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Exonuc_VII_L PF02601.15 EEQ33361.1 - 0.12 11.9 1.0 0.19 11.3 1.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 EEQ33361.1 - 0.73 10.2 6.4 0.35 11.2 3.8 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SMC_N PF02463.19 EEQ33362.1 - 2.4e-59 200.5 0.0 5.4e-37 127.3 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEQ33362.1 - 7.4e-30 103.7 3.2 1.1e-29 103.2 0.0 3.0 3 1 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EEQ33362.1 - 2.2e-11 44.7 16.6 2.2e-11 44.7 16.6 6.6 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 EEQ33362.1 - 3.8e-10 40.1 6.3 1.6e-06 28.2 2.2 4.4 3 2 2 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ33362.1 - 6.7e-08 32.2 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EEQ33362.1 - 9.7e-06 25.5 14.0 9.7e-06 25.5 14.0 4.8 2 2 2 4 4 4 1 AAA ATPase domain CALCOCO1 PF07888.11 EEQ33362.1 - 0.0021 17.0 3.7 0.0021 17.0 3.7 5.3 3 2 1 5 5 5 1 Calcium binding and coiled-coil domain (CALCOCO1) like SbcCD_C PF13558.6 EEQ33362.1 - 0.003 17.8 0.0 0.021 15.1 0.0 2.5 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF1664 PF07889.12 EEQ33362.1 - 0.01 15.8 60.3 0.044 13.8 4.4 8.7 5 4 4 9 9 9 0 Protein of unknown function (DUF1664) DUF2939 PF11159.8 EEQ33362.1 - 3 8.3 5.3 18 5.9 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) E3_binding PF02817.17 EEQ33364.1 - 2.3e-12 47.0 0.2 1.6e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 e3 binding domain ABC_membrane PF00664.23 EEQ33365.1 - 6.8e-82 275.2 37.4 3.7e-43 148.2 12.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ33365.1 - 4.6e-72 240.9 0.0 5.1e-35 121.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ33365.1 - 5.5e-14 52.1 1.0 0.0022 17.5 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EEQ33365.1 - 1e-09 39.0 0.2 7.6e-05 23.2 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EEQ33365.1 - 3.1e-09 36.4 1.7 0.0011 18.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EEQ33365.1 - 8.1e-09 34.8 0.7 0.0011 17.9 0.2 3.5 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EEQ33365.1 - 1.1e-06 29.0 0.1 0.1 12.9 0.0 3.4 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EEQ33365.1 - 5.3e-06 26.4 0.0 0.043 13.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EEQ33365.1 - 1.4e-05 25.0 0.1 0.11 12.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EEQ33365.1 - 8.7e-05 21.9 0.1 0.43 9.8 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_23 PF13476.6 EEQ33365.1 - 0.00013 22.5 0.6 0.3 11.6 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EEQ33365.1 - 0.00013 22.5 0.0 0.15 12.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEQ33365.1 - 0.00014 21.6 0.0 0.57 9.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 EEQ33365.1 - 0.00023 21.3 0.2 0.28 11.3 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 EEQ33365.1 - 0.00026 20.8 0.1 0.14 11.8 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EEQ33365.1 - 0.00026 21.0 0.0 0.36 10.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EEQ33365.1 - 0.00032 20.5 0.0 0.37 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EEQ33365.1 - 0.00091 18.9 0.0 0.46 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EEQ33365.1 - 0.0013 18.7 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA PF00004.29 EEQ33365.1 - 0.0014 19.1 0.3 0.78 10.2 0.0 4.2 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EEQ33365.1 - 0.0014 18.2 0.1 0.51 9.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region G-alpha PF00503.20 EEQ33365.1 - 0.0015 17.7 0.0 0.17 11.0 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 EEQ33365.1 - 0.0016 18.3 0.0 2 8.2 0.0 2.7 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 EEQ33365.1 - 0.0017 18.5 0.1 1.7 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EEQ33365.1 - 0.0023 17.7 0.1 1.4 8.6 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase ATP-synt_ab PF00006.25 EEQ33365.1 - 0.0069 16.1 0.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 EEQ33365.1 - 0.0094 15.9 0.4 24 4.8 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 EEQ33365.1 - 0.013 15.7 0.3 1.6 8.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EEQ33365.1 - 0.014 15.1 0.5 0.35 10.6 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein Rad17 PF03215.15 EEQ33365.1 - 0.028 14.3 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EEQ33365.1 - 0.044 13.9 1.1 6.8 6.8 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 EEQ33365.1 - 0.045 14.0 2.4 9.2 6.6 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EEQ33365.1 - 0.061 13.5 0.4 4.3 7.6 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EEQ33365.1 - 0.062 13.7 0.0 13 6.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 EEQ33365.1 - 0.16 11.7 0.2 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AMP-binding PF00501.28 EEQ33366.1 - 1e-214 712.9 0.0 7.2e-75 252.2 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EEQ33366.1 - 2.4e-132 441.9 0.0 7.3e-38 130.4 0.0 7.9 6 2 0 7 7 7 5 Condensation domain PP-binding PF00550.25 EEQ33366.1 - 1.9e-28 98.6 0.1 1.1e-12 48.1 0.0 4.4 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ33366.1 - 2.5e-05 25.2 0.0 0.015 16.2 0.0 3.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EEQ33366.1 - 0.00075 18.3 0.0 0.088 11.4 0.0 2.7 3 0 0 3 3 3 2 Transferase family DUF1324 PF07038.11 EEQ33366.1 - 0.058 13.6 2.1 0.15 12.3 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) WD40 PF00400.32 EEQ33367.1 - 2.9e-24 84.9 12.7 0.00014 22.6 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33367.1 - 3.7e-14 52.8 6.4 0.00033 20.9 0.3 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ33367.1 - 7e-08 32.6 0.1 0.0081 16.1 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 EEQ33367.1 - 0.017 14.0 0.9 3.8 6.3 0.1 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 EEQ33367.1 - 0.023 13.6 0.0 0.064 12.2 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M18 PF02127.15 EEQ33368.1 - 2.9e-166 553.6 0.0 3.3e-166 553.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) MFS_1 PF07690.16 EEQ33369.1 - 1.3e-46 159.1 47.7 1.5e-36 126.1 30.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ33369.1 - 2.7e-45 155.1 11.8 4e-45 154.5 11.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EEQ33369.1 - 0.00013 21.0 13.1 0.016 14.0 3.0 3.1 1 1 2 3 3 3 3 MFS_1 like family OATP PF03137.20 EEQ33369.1 - 0.0015 16.9 0.9 0.0015 16.9 0.9 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 EEQ33369.1 - 0.003 16.2 1.2 0.003 16.2 1.2 2.3 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like Sigma70_r4 PF04545.16 EEQ33369.1 - 0.025 14.1 0.7 9.5 5.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 VirB3 PF05101.13 EEQ33369.1 - 0.63 10.3 0.0 0.63 10.3 0.0 4.0 4 1 0 4 4 4 0 Type IV secretory pathway, VirB3-like protein Hydrolase_6 PF13344.6 EEQ33370.1 - 2.7e-29 101.2 0.0 5.3e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ33370.1 - 4.5e-16 58.7 0.1 9.6e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EEQ33370.1 - 1.2e-10 42.0 0.1 0.0004 20.7 0.0 3.1 1 1 2 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ33370.1 - 3.8e-06 27.1 0.2 0.081 13.0 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EEQ33370.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) RRG8 PF17068.5 EEQ33371.1 - 0.056 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial DUF1746 PF08508.10 EEQ33372.1 - 7.5e-45 152.0 1.0 1e-44 151.5 1.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.23 EEQ33373.1 - 3.6e-76 255.1 0.0 4.4e-76 254.8 0.0 1.0 1 0 0 1 1 1 1 Clp protease DHDPS PF00701.22 EEQ33373.1 - 0.0071 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Tugs PF17840.1 EEQ33373.1 - 1 9.6 3.4 0.81 9.9 0.6 2.0 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain Rep_fac_C PF08542.11 EEQ33374.1 - 7.1e-22 77.6 0.0 1.7e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EEQ33374.1 - 4e-12 46.7 0.0 1.7e-11 44.7 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EEQ33374.1 - 3.1e-11 43.3 0.0 4.9e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EEQ33374.1 - 1e-08 35.3 0.0 4e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EEQ33374.1 - 1.8e-05 25.0 0.3 8.1e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 AAA C-terminal domain AAA_11 PF13086.6 EEQ33374.1 - 6.5e-05 22.8 0.0 0.00016 21.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EEQ33374.1 - 0.0011 18.8 0.1 0.0027 17.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEQ33374.1 - 0.0021 18.4 0.1 0.02 15.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EEQ33374.1 - 0.0023 17.3 0.0 0.077 12.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EEQ33374.1 - 0.0028 16.9 0.0 0.0053 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EEQ33374.1 - 0.0068 16.1 0.0 0.022 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ33374.1 - 0.0072 16.7 0.0 0.053 13.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEQ33374.1 - 0.0095 16.2 0.2 0.31 11.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EEQ33374.1 - 0.035 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 EEQ33374.1 - 0.046 13.0 0.0 0.15 11.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EEQ33374.1 - 0.15 12.1 0.1 4.5 7.3 0.0 2.8 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit MFS_1 PF07690.16 EEQ33375.1 - 9.8e-43 146.4 50.4 9.8e-43 146.4 50.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ33375.1 - 2.9e-15 55.7 15.9 5.2e-15 54.9 15.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ33375.1 - 4.1e-10 39.1 16.0 4.1e-10 39.1 16.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3522 PF12036.8 EEQ33375.1 - 0.002 18.4 4.0 0.0072 16.6 0.6 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3522) YpmT PF17431.2 EEQ33375.1 - 0.046 13.7 0.9 0.32 11.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized YmpT-like Sec20 PF03908.13 EEQ33376.1 - 3.9e-16 58.7 2.8 4.8e-16 58.5 1.7 1.7 2 0 0 2 2 2 1 Sec20 Syntaxin-6_N PF09177.11 EEQ33376.1 - 0.066 13.8 6.3 0.16 12.5 0.6 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal SOGA PF11365.8 EEQ33376.1 - 0.96 10.6 7.8 2.9 9.1 0.6 3.2 3 0 0 3 3 3 0 Protein SOGA MRP_L53 PF10780.9 EEQ33377.1 - 3.3e-16 59.2 0.2 4.3e-16 58.8 0.2 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 RPN5_C PF18098.1 EEQ33377.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain Pyrophosphatase PF00719.19 EEQ33378.1 - 5.6e-15 55.5 0.1 1.9e-12 47.3 0.0 2.2 1 1 1 2 2 2 2 Inorganic pyrophosphatase Dus PF01207.17 EEQ33379.1 - 3.4e-43 147.9 0.0 6.8e-43 146.9 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PucR PF07905.11 EEQ33379.1 - 0.095 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Peptidase_M28 PF04389.17 EEQ33380.1 - 4.2e-42 144.1 0.1 6.7e-42 143.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EEQ33380.1 - 1.9e-13 50.2 3.4 2.8e-13 49.7 0.4 2.5 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EEQ33380.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EEQ33380.1 - 0.055 12.5 0.0 0.34 9.9 0.0 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase SNF2_N PF00176.23 EEQ33382.1 - 5.1e-52 176.7 0.2 8.4e-52 176.0 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ33382.1 - 9.9e-20 71.0 0.7 1.2e-18 67.5 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ33382.1 - 1.6e-08 34.8 0.0 4.6e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EEQ33382.1 - 1.8e-05 24.1 0.1 3.7e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EEQ33382.1 - 4.2e-05 23.4 0.0 9.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_2 PF12796.7 EEQ33384.1 - 4e-104 341.4 18.2 4.9e-14 52.7 0.6 11.2 6 3 4 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ33384.1 - 4.8e-85 278.9 15.8 1.2e-09 38.5 0.1 17.8 6 4 15 21 21 21 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ33384.1 - 1.6e-76 243.0 24.3 0.00011 22.3 0.0 21.6 23 0 0 23 23 23 14 Ankyrin repeat Ank PF00023.30 EEQ33384.1 - 3.6e-61 201.1 43.4 0.00032 21.0 0.1 21.6 20 2 2 22 22 22 16 Ankyrin repeat Ank_5 PF13857.6 EEQ33384.1 - 1.9e-40 136.4 33.8 0.0013 18.9 0.3 16.8 10 6 7 17 17 17 14 Ankyrin repeats (many copies) Clr5 PF14420.6 EEQ33384.1 - 4.9e-11 42.7 1.7 1.1e-10 41.6 1.7 1.6 1 0 0 1 1 1 1 Clr5 domain DUF3447 PF11929.8 EEQ33384.1 - 6.9e-05 22.7 0.0 9.1 6.3 0.0 6.0 4 2 2 6 6 6 1 Domain of unknown function (DUF3447) Reductase_C PF14759.6 EEQ33384.1 - 0.013 16.0 3.4 16 6.2 0.0 5.9 6 0 0 6 6 6 0 Reductase C-terminal Shigella_OspC PF06128.11 EEQ33384.1 - 0.022 14.5 1.4 56 3.3 0.1 5.5 5 2 0 6 6 6 0 Shigella flexneri OspC protein Glyco_hydro_18 PF00704.28 EEQ33387.1 - 2.2e-39 136.0 2.3 4.1e-39 135.1 2.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EEQ33387.1 - 1.2e-08 34.8 0.0 0.00079 19.4 0.0 3.4 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 EEQ33387.1 - 9.4e-06 26.0 8.5 9.4e-06 26.0 8.5 3.1 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 EEQ33389.1 - 1.8e-08 34.3 0.2 1.8e-05 24.7 0.0 2.8 3 0 0 3 3 3 2 LysM domain DUF647 PF04884.14 EEQ33389.1 - 0.066 12.8 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis APH PF01636.23 EEQ33390.1 - 4.4e-06 26.8 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Lipoprotein_7 PF01540.16 EEQ33391.1 - 0.01 15.2 0.1 0.012 14.9 0.1 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein TRAM_LAG1_CLN8 PF03798.16 EEQ33392.1 - 9e-36 123.5 15.2 1.8e-35 122.5 15.2 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EEQ33392.1 - 9.6e-25 86.0 0.2 2.5e-24 84.7 0.2 1.7 1 0 0 1 1 1 1 TRAM1-like protein YkuD PF03734.14 EEQ33392.1 - 0.093 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain YwiC PF14256.6 EEQ33392.1 - 8 6.8 10.0 13 6.2 1.8 3.2 3 1 1 4 4 4 0 YwiC-like protein Hira PF07569.11 EEQ33393.1 - 2.2e-79 266.3 0.0 4.7e-79 265.2 0.0 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EEQ33393.1 - 4.9e-28 96.8 26.7 6.9e-05 23.5 0.0 9.7 9 1 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33393.1 - 2.9e-14 53.1 0.1 0.1 12.9 0.0 6.5 4 1 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EEQ33393.1 - 3.9e-09 36.2 0.0 1e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EEQ33393.1 - 1.2e-06 28.3 4.1 0.43 10.6 0.0 5.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EEQ33393.1 - 0.00029 19.9 1.1 1.6 7.6 0.0 5.0 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EEQ33393.1 - 0.0027 15.8 0.0 0.007 14.4 0.0 1.6 1 1 1 2 2 2 1 IKI3 family YchF-GTPase_C PF06071.13 EEQ33394.1 - 2.3e-33 114.2 0.1 5e-33 113.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EEQ33394.1 - 1.1e-17 64.2 0.0 3.5e-17 62.5 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ33394.1 - 0.00097 18.7 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EEQ33394.1 - 0.014 15.4 0.1 0.051 13.6 0.1 2.0 2 1 0 2 2 2 0 TGS domain Pre-PUA PF17832.1 EEQ33395.1 - 2.1e-22 79.6 0.1 2.7e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EEQ33395.1 - 2.5e-13 49.8 0.2 3.7e-13 49.3 0.2 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 EEQ33395.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) RIC1 PF07064.13 EEQ33396.1 - 2.6e-79 266.2 0.0 3.6e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 RIC1 SGTA_dimer PF16546.5 EEQ33397.1 - 4.9e-24 83.9 0.4 1.1e-23 82.8 0.1 1.7 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 EEQ33397.1 - 3.5e-13 48.5 7.6 0.00036 20.4 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ33397.1 - 1e-12 47.3 5.7 4.7e-05 23.0 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ33397.1 - 4.6e-11 42.2 4.8 5.1e-08 32.5 0.9 2.7 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 EEQ33397.1 - 8.5e-08 32.7 18.9 3.6e-05 24.3 4.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ33397.1 - 3.7e-06 26.7 5.0 0.12 12.6 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ33397.1 - 9.6e-06 25.8 2.9 0.00021 21.5 0.5 2.9 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ33397.1 - 3.2e-05 24.0 1.4 0.00049 20.2 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ33397.1 - 4.1e-05 24.0 5.7 0.095 13.6 0.6 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ33397.1 - 0.00017 21.7 1.3 0.31 11.5 0.6 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ33397.1 - 0.00032 20.5 0.2 9.8 6.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 EEQ33397.1 - 0.0016 18.4 13.4 0.0089 15.9 8.1 2.9 3 0 0 3 3 3 1 STI1 domain TPR_19 PF14559.6 EEQ33397.1 - 0.0016 18.9 1.5 0.013 16.0 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ33397.1 - 0.004 17.0 3.9 0.13 12.2 0.6 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat XPC-binding PF09280.11 EEQ33397.1 - 0.018 14.7 4.3 0.044 13.5 3.9 1.8 2 0 0 2 2 2 0 XPC-binding domain TPR_15 PF13429.6 EEQ33397.1 - 0.073 12.3 0.3 0.12 11.5 0.3 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat GerD PF17898.1 EEQ33397.1 - 0.16 11.9 2.3 0.62 10.0 0.9 2.4 2 0 0 2 2 2 0 Spore germination GerD central core domain TPR_6 PF13174.6 EEQ33397.1 - 0.99 10.2 4.7 20 6.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim44 PF04280.15 EEQ33398.1 - 1.4e-37 129.0 1.4 1.9e-37 128.6 0.0 2.0 3 0 0 3 3 3 1 Tim44-like domain Spt20 PF12090.8 EEQ33398.1 - 0.89 9.1 9.9 1.4 8.4 9.9 1.4 1 0 0 1 1 1 0 Spt20 family Ribosomal_S11 PF00411.19 EEQ33399.1 - 1.8e-07 31.5 0.0 5.2e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S11 GHBP PF12772.7 EEQ33399.1 - 0.082 12.4 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Growth hormone receptor binding VPS9 PF02204.18 EEQ33400.1 - 2e-18 66.5 0.0 7.3e-18 64.7 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EEQ33400.1 - 4e-17 62.0 0.1 9e-14 51.4 0.0 4.2 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ33400.1 - 1.6e-12 47.8 0.0 0.00027 21.4 0.0 3.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEQ33400.1 - 1.1e-05 25.4 0.1 0.6 10.8 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EEQ33400.1 - 3.9e-05 24.1 0.1 0.36 11.5 0.0 5.0 4 1 0 4 4 4 1 Ankyrin repeats (many copies) PX PF00787.24 EEQ33400.1 - 0.00011 22.2 0.1 0.00027 20.9 0.1 1.6 1 0 0 1 1 1 1 PX domain Ank PF00023.30 EEQ33400.1 - 0.015 15.8 1.9 12 6.5 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeat TNFR_16_TM PF18422.1 EEQ33401.1 - 0.08 12.9 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain EphA2_TM PF14575.6 EEQ33401.1 - 0.18 12.7 0.0 0.39 11.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Inhibitor_I78 PF11720.8 EEQ33402.1 - 1.6e-10 40.9 0.0 3.3e-09 36.7 0.0 2.0 2 0 0 2 2 2 2 Peptidase inhibitor I78 family Nefa_Nip30_N PF10187.9 EEQ33403.1 - 3.3e-32 111.0 10.4 7.1e-32 109.9 10.4 1.6 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2570 PF10828.8 EEQ33403.1 - 0.14 12.0 2.2 0.23 11.3 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) CK_II_beta PF01214.18 EEQ33405.1 - 3.2e-77 258.5 0.1 3.2e-77 258.5 0.1 1.4 2 0 0 2 2 2 1 Casein kinase II regulatory subunit RNA_pol_3_Rpc31 PF11705.8 EEQ33405.1 - 0.0058 16.9 4.1 0.0083 16.4 4.1 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF3306 PF11748.8 EEQ33405.1 - 0.11 13.4 0.5 0.11 13.4 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) CENP-B_dimeris PF09026.10 EEQ33405.1 - 1.6 9.2 11.0 4.3 7.8 11.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Astro_capsid_p PF12226.8 EEQ33405.1 - 2.2 7.4 5.4 3.2 6.8 5.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 EEQ33405.1 - 7.6 4.7 6.4 11 4.2 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein E1-E2_ATPase PF00122.20 EEQ33406.1 - 1.4e-46 158.3 2.5 1.4e-46 158.3 2.5 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EEQ33406.1 - 3.7e-26 92.7 0.3 7.9e-26 91.7 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EEQ33406.1 - 4.4e-10 39.9 0.1 2.8e-08 34.1 0.0 2.6 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EEQ33406.1 - 0.00029 20.7 0.4 0.19 11.4 0.1 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase MinC_N PF05209.13 EEQ33406.1 - 0.073 13.0 0.2 17 5.4 0.1 2.6 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain HAD PF12710.7 EEQ33406.1 - 0.099 13.0 0.0 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 EEQ33407.1 - 8.6e-37 126.8 0.4 1e-18 67.4 0.2 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ33407.1 - 1.2e-06 28.5 12.8 2.4e-06 27.6 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 EEQ33408.1 - 1.2e-08 35.0 0.1 4.1e-08 33.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ33408.1 - 0.00021 22.0 0.6 0.00027 21.6 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.8 EEQ33408.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3089) DUF915 PF06028.11 EEQ33408.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 EEQ33408.1 - 0.021 14.1 0.1 0.026 13.8 0.1 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ33408.1 - 0.024 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EEQ33408.1 - 0.025 14.3 0.1 0.072 12.8 0.1 1.8 1 1 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 EEQ33408.1 - 0.039 13.4 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 EEQ33408.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.13 EEQ33408.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase EB PF01683.18 EEQ33409.1 - 3.6 8.0 39.9 0.13 12.6 9.8 5.2 3 2 2 5 5 5 0 EB module JAB PF01398.21 EEQ33410.1 - 3.8e-07 30.1 0.2 1.7e-05 24.8 0.2 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Trypan_PARP PF05887.11 EEQ33412.1 - 0.0027 17.7 32.5 0.0027 17.7 32.5 14.6 6 3 9 16 16 16 1 Procyclic acidic repetitive protein (PARP) HMG_box PF00505.19 EEQ33413.1 - 5.7e-07 29.9 3.6 5.7e-07 29.9 3.6 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EEQ33413.1 - 0.00018 22.0 5.3 0.00018 22.0 5.3 2.7 2 0 0 2 2 2 1 HMG-box domain XFP_N PF09364.10 EEQ33413.1 - 0.054 12.3 0.3 0.075 11.8 0.3 1.2 1 0 0 1 1 1 0 XFP N-terminal domain Protamine_like PF06382.11 EEQ33413.1 - 8 6.6 10.7 0.05 13.8 0.9 2.0 2 0 0 2 2 2 0 Protamine and protamine like DEAD PF00270.29 EEQ33414.1 - 3.2e-49 167.1 0.0 9.9e-49 165.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ33414.1 - 1e-26 93.5 0.0 3.5e-26 91.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ33414.1 - 0.0023 17.9 0.0 0.021 14.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WLM PF08325.10 EEQ33415.1 - 0.089 12.9 0.1 0.089 12.9 0.1 1.4 2 0 0 2 2 2 0 WLM domain zf-C2H2 PF00096.26 EEQ33416.1 - 4.2e-18 64.7 44.2 8e-07 29.2 0.9 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ33416.1 - 4.1e-15 55.4 38.6 5.8e-08 32.8 0.8 6.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ33416.1 - 3.9e-13 49.0 32.5 0.00021 21.8 0.6 7.6 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.7 EEQ33416.1 - 2.6e-11 43.5 4.7 0.00036 20.8 0.3 5.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEQ33416.1 - 5.3e-11 42.5 0.6 0.0035 17.6 0.3 4.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EEQ33416.1 - 4.4e-06 26.6 15.2 0.00055 19.9 0.6 5.0 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EEQ33416.1 - 7e-06 25.7 2.1 0.095 12.5 0.2 3.8 3 0 0 3 3 3 2 zinc-finger C2H2-type zf_UBZ PF18439.1 EEQ33416.1 - 0.00029 20.4 2.1 4.2 7.0 0.1 3.8 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 EEQ33416.1 - 0.0021 17.9 9.7 0.037 13.9 0.3 4.6 4 0 0 4 4 4 1 zinc-finger of a C2HC-type BolA PF01722.18 EEQ33416.1 - 0.0059 16.9 0.2 1.7 9.0 0.0 2.5 1 1 1 2 2 2 2 BolA-like protein DUF533 PF04391.12 EEQ33418.1 - 0.093 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) zf-C2H2 PF00096.26 EEQ33419.1 - 2.2e-06 27.8 13.8 3.6e-05 24.0 3.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ33419.1 - 5.1e-06 26.7 3.2 5.1e-06 26.7 3.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 EEQ33419.1 - 0.0003 21.1 6.6 0.0017 18.6 0.9 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EEQ33419.1 - 0.0016 19.1 1.9 0.0016 19.1 1.9 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger DUF2225 PF09986.9 EEQ33419.1 - 0.0043 16.8 0.1 0.0073 16.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.6 EEQ33419.1 - 0.0045 17.0 1.5 0.013 15.5 1.5 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ33419.1 - 0.013 15.8 0.9 0.043 14.1 0.9 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EEQ33419.1 - 0.18 12.1 5.6 0.41 11.0 5.6 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_2 PF13923.6 EEQ33420.1 - 0.044 13.6 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FIT1_2 PF17357.2 EEQ33422.1 - 0.7 10.0 8.2 1.4 9.0 8.2 1.5 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 SKG6 PF08693.10 EEQ33422.1 - 1.4 8.4 2.9 2.6 7.5 2.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HAT PF02184.16 EEQ33423.1 - 1.8e-26 91.8 74.8 1.9e-16 59.7 2.6 13.3 14 0 0 14 14 14 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EEQ33423.1 - 4.5e-18 64.4 23.3 0.0037 18.0 0.1 11.0 5 2 9 14 14 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ33423.1 - 1.9e-16 60.3 0.0 0.0012 19.3 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat Suf PF05843.14 EEQ33423.1 - 4.7e-13 49.8 30.6 0.00017 21.7 3.3 6.8 2 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EEQ33423.1 - 1.6e-07 31.2 4.3 0.59 10.6 0.0 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ33423.1 - 7.2e-07 28.9 2.5 6.6 7.2 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ33423.1 - 4.4e-06 26.4 7.6 2.8 8.3 0.0 7.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ33423.1 - 5.8e-05 23.5 20.0 0.71 10.6 0.0 8.3 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ33423.1 - 6.6e-05 23.5 2.2 16 6.2 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ33423.1 - 0.0073 16.1 1.1 45 4.1 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ER PF01133.17 EEQ33423.1 - 0.24 11.4 2.5 4.3 7.4 0.4 3.9 3 1 1 4 4 4 0 Enhancer of rudimentary TPR_12 PF13424.6 EEQ33423.1 - 0.6 10.4 14.2 8.2 6.8 0.1 6.2 6 2 0 6 6 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EEQ33423.1 - 1 9.5 32.2 0.045 13.8 2.2 7.1 7 3 2 9 9 9 0 U3 small nucleolar RNA-associated protein 6 ECSIT PF06239.11 EEQ33423.1 - 4.6 6.3 9.7 0.089 11.9 0.2 2.8 4 0 0 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway Nop PF01798.18 EEQ33424.1 - 1.1e-70 237.7 0.0 1.5e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EEQ33424.1 - 5.6e-47 159.6 1.5 1.1e-46 158.7 1.5 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain RRN3 PF05327.11 EEQ33424.1 - 1.6 7.1 4.8 2.4 6.6 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AdoHcyase PF05221.17 EEQ33425.1 - 1.4e-129 431.5 0.0 1.1e-73 248.0 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EEQ33425.1 - 2.5e-84 281.2 2.3 5.2e-84 280.2 2.3 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EEQ33425.1 - 2.8e-07 30.0 0.1 5.8e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EEQ33425.1 - 0.0001 21.9 0.2 0.00018 21.1 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EEQ33425.1 - 0.0021 18.3 0.1 0.0049 17.1 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain EC042_2821 PF18740.1 EEQ33426.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 EC042_2821-lke REase DUF3759 PF12585.8 EEQ33427.1 - 3.5e-38 129.5 7.8 4.1e-38 129.3 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Peptidase_C13 PF01650.18 EEQ33428.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family PAS_3 PF08447.12 EEQ33428.1 - 0.16 12.3 0.1 3.7 7.9 0.0 2.5 2 0 0 2 2 2 0 PAS fold Band_7 PF01145.25 EEQ33429.1 - 6.2e-30 104.5 0.8 6.2e-30 104.5 0.8 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EEQ33429.1 - 2.1e-23 82.1 2.3 2.1e-23 82.1 2.3 2.2 2 0 0 2 2 2 1 C-terminal region of band_7 Pox_A11 PF05061.13 EEQ33429.1 - 0.023 14.0 0.5 0.035 13.4 0.5 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 EEQ33429.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family RecX PF02631.16 EEQ33429.1 - 0.11 13.0 0.3 0.11 13.0 0.3 2.2 2 1 0 3 3 3 0 RecX family Mod_r PF07200.13 EEQ33431.1 - 4.2e-28 98.3 0.3 5.4e-28 97.9 0.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein GIT_CC PF16559.5 EEQ33431.1 - 0.0096 15.8 0.3 0.018 14.9 0.3 1.4 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor PSK_trans_fac PF07704.11 EEQ33431.1 - 0.72 10.6 3.6 0.35 11.7 1.1 1.7 2 0 0 2 2 2 0 Rv0623-like transcription factor PAP2 PF01569.21 EEQ33432.1 - 5.4e-20 71.6 0.8 5.4e-20 71.6 0.8 2.0 2 1 0 2 2 2 1 PAP2 superfamily Aldo_ket_red PF00248.21 EEQ33433.1 - 4.4e-47 160.7 0.1 7e-47 160.0 0.1 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.14 EEQ33435.1 - 9.9e-08 32.2 0.2 2e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.13 EEQ33436.1 - 2.4e-05 24.4 0.4 3.6e-05 23.8 0.4 1.3 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 EEQ33436.1 - 0.0047 17.2 1.5 0.3 11.4 0.1 2.2 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 EEQ33436.1 - 0.0084 16.4 1.2 0.024 14.9 1.3 1.6 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 NPR3 PF03666.13 EEQ33437.1 - 2e-154 514.9 0.0 2e-154 514.9 0.0 2.6 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 EEQ33437.1 - 0.0054 15.5 0.0 0.018 13.8 0.1 1.7 2 0 0 2 2 2 1 Nitrogen permease regulator 2 La PF05383.17 EEQ33438.1 - 8.5e-19 67.4 0.4 1.6e-18 66.5 0.4 1.4 1 0 0 1 1 1 1 La domain Ank_4 PF13637.6 EEQ33440.1 - 9.5e-10 38.8 0.0 2.6e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ33440.1 - 1.9e-09 37.6 0.1 3.1e-08 33.7 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ33440.1 - 5.8e-07 30.0 0.1 1.3e-06 28.9 0.1 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEQ33440.1 - 3e-06 27.1 0.1 0.00031 21.0 0.1 2.9 2 1 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EEQ33440.1 - 0.004 17.5 0.0 0.044 14.3 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat YejG PF13989.6 EEQ33440.1 - 0.17 12.3 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein F-box PF00646.33 EEQ33441.1 - 0.022 14.6 0.0 0.022 14.6 0.0 3.6 5 0 0 5 5 5 0 F-box domain F-box-like PF12937.7 EEQ33441.1 - 0.031 14.2 1.0 0.071 13.0 0.0 2.1 2 0 0 2 2 2 0 F-box-like PIF PF05092.12 EEQ33441.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity tRNA_lig_CPD PF08302.11 EEQ33442.1 - 1.4e-92 309.7 0.0 2e-92 309.2 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 EEQ33442.1 - 3.3e-85 285.4 0.0 6.5e-85 284.5 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EEQ33442.1 - 2.6e-45 154.5 0.9 9.5e-45 152.7 0.5 2.2 2 1 0 2 2 2 1 tRNA ligase kinase domain AAA_18 PF13238.6 EEQ33442.1 - 0.022 15.3 0.3 0.25 11.9 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF4150 PF13665.6 EEQ33442.1 - 0.051 13.7 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) HLH PF00010.26 EEQ33443.1 - 4.7e-10 39.3 0.0 1.6e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_carr PF00153.27 EEQ33444.1 - 8.8e-44 147.4 2.8 2.9e-18 65.6 0.1 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein Dna2 PF08696.11 EEQ33445.1 - 9.8e-68 228.0 0.0 1.9e-67 227.0 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 EEQ33445.1 - 1.1e-54 185.1 0.0 1.8e-54 184.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEQ33445.1 - 2.2e-34 119.5 0.1 7.5e-18 65.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EEQ33445.1 - 1.1e-13 51.4 0.0 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ33445.1 - 2.8e-11 44.0 0.1 7.3e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 EEQ33445.1 - 2.3e-08 34.2 0.0 4.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 EEQ33445.1 - 5.8e-07 29.5 0.4 0.22 11.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 EEQ33445.1 - 4.1e-06 27.0 0.0 0.52 10.4 0.0 3.5 2 1 0 2 2 2 1 Domain of unknown function DUF83 Helicase_RecD PF05127.14 EEQ33445.1 - 0.00013 21.9 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 EEQ33445.1 - 0.00035 20.2 0.8 0.00092 18.8 0.1 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 EEQ33445.1 - 0.0012 18.5 0.1 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.14 EEQ33445.1 - 0.0031 16.8 0.0 0.0067 15.6 0.0 1.6 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 EEQ33445.1 - 0.0073 16.7 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EEQ33445.1 - 0.023 14.0 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 EEQ33445.1 - 0.035 13.5 0.1 0.088 12.1 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family CbiA PF01656.23 EEQ33445.1 - 0.042 13.9 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 EEQ33445.1 - 0.048 13.2 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 EEQ33445.1 - 0.059 13.5 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain ResIII PF04851.15 EEQ33445.1 - 0.064 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 EEQ33445.1 - 0.072 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EEQ33445.1 - 0.083 12.8 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.6 EEQ33445.1 - 0.087 12.4 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EEQ33445.1 - 0.11 12.2 0.1 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.14 EEQ33445.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 EEQ33445.1 - 0.13 12.4 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain MeaB PF03308.16 EEQ33445.1 - 0.16 10.9 0.1 0.35 9.8 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ribonuc_P_40 PF08584.11 EEQ33446.1 - 2.1e-73 247.1 0.0 2.8e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.32 EEQ33447.1 - 1.9e-27 94.9 13.9 6.1e-07 30.0 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33447.1 - 4.6e-15 55.7 0.0 0.0024 18.1 0.0 5.6 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EEQ33447.1 - 9.4e-07 27.7 0.0 0.0026 16.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EEQ33447.1 - 0.00084 19.3 0.0 2.5 7.9 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EEQ33447.1 - 0.039 12.9 0.0 2.7 6.9 0.0 3.0 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEQ33447.1 - 0.24 10.0 0.2 8.6 4.9 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Fungal_trans PF04082.18 EEQ33448.1 - 2.2e-16 59.7 0.2 3.9e-16 58.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ33448.1 - 3.3e-10 39.9 9.3 6.9e-10 38.9 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.18 EEQ33449.1 - 5.4e-48 162.4 1.6 7.9e-34 116.6 1.2 2.6 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EEQ33449.1 - 1.4e-25 89.1 0.4 3e-25 88.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 EEQ33450.1 - 2.6e-45 153.2 0.0 2.4e-44 150.1 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEQ33450.1 - 9.1e-32 109.7 0.0 1.6e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.23 EEQ33451.1 - 9.5e-17 61.6 0.1 2.9e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EEQ33451.1 - 6e-06 26.7 0.0 1.3e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EEQ33451.1 - 0.028 14.3 0.2 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.18 EEQ33452.1 - 2e-09 37.4 0.0 8.4e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 EEQ33452.1 - 5.9e-06 25.8 0.0 9.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 EEQ33452.1 - 0.14 11.8 0.1 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF2985 PF11204.8 EEQ33454.1 - 9.7e-22 76.9 3.9 1.9e-21 76.0 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) SIR2 PF02146.17 EEQ33455.1 - 1.1e-58 198.1 0.0 1.6e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EEQ33455.1 - 1.3e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EEQ33455.1 - 0.00058 19.6 0.5 1.1 9.0 0.0 2.7 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain SDP_N PF12278.8 EEQ33455.1 - 0.25 11.5 0.9 7 6.8 0.3 2.3 2 0 0 2 2 2 0 Sex determination protein N terminal TPR_2 PF07719.17 EEQ33456.1 - 8.7e-13 47.3 0.0 8.1e-05 22.5 0.0 5.5 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ33456.1 - 1.3e-12 47.8 0.0 5.9e-08 32.9 0.0 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ33456.1 - 3.9e-11 43.3 0.7 4.2e-05 24.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ33456.1 - 1.1e-08 34.5 0.0 0.0021 17.8 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ33456.1 - 2.1e-08 34.3 5.7 0.12 13.3 0.0 5.4 5 2 1 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ33456.1 - 2.5e-08 34.4 0.0 5.7e-05 23.7 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ33456.1 - 1.4e-07 31.2 0.0 0.00073 19.6 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ33456.1 - 2.4e-06 27.6 0.7 0.61 10.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ33456.1 - 6.9e-06 25.7 0.0 0.051 13.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ33456.1 - 2.9e-05 24.2 0.0 31 5.3 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ33456.1 - 2.9e-05 23.7 0.1 0.00033 20.3 0.0 2.5 2 0 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 EEQ33456.1 - 8.7e-05 22.7 0.0 0.3 11.4 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EEQ33456.1 - 0.00045 20.0 0.1 1.3 9.0 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EEQ33456.1 - 0.00075 19.3 0.0 0.036 13.8 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_5 PF12688.7 EEQ33456.1 - 0.0023 18.1 0.1 0.019 15.2 0.0 2.5 1 1 1 2 2 2 1 Tetratrico peptide repeat Coatomer_E PF04733.14 EEQ33456.1 - 0.0024 17.4 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_4 PF07721.14 EEQ33456.1 - 0.0029 18.1 3.9 0.038 14.6 0.0 3.4 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ33456.1 - 0.0033 16.9 0.0 0.31 10.4 0.0 2.4 2 0 0 2 2 2 1 MalT-like TPR region SHNi-TPR PF10516.9 EEQ33456.1 - 0.0033 16.8 0.5 0.21 11.1 0.0 2.6 2 0 0 2 2 2 1 SHNi-TPR TPR_15 PF13429.6 EEQ33456.1 - 0.0046 16.2 0.1 0.25 10.5 0.0 3.0 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ33456.1 - 0.0048 17.5 0.6 9.1 7.2 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat RWD PF05773.22 EEQ33457.1 - 1.5e-24 86.5 1.2 1.5e-24 86.5 1.2 1.7 2 1 0 2 2 2 1 RWD domain DFRP_C PF16543.5 EEQ33457.1 - 0.00024 21.5 13.8 0.0014 19.1 13.7 2.3 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF1682 PF07946.14 EEQ33457.1 - 0.0028 16.9 7.7 0.004 16.4 7.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Jak1_Phl PF17887.1 EEQ33457.1 - 0.77 9.7 4.5 1.3 9.0 4.5 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain MPM1 PF17234.2 EEQ33457.1 - 1.7 8.9 10.2 1.2 9.4 8.1 1.5 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Putative_PNPOx PF01243.20 EEQ33458.1 - 4.7e-05 23.5 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GST_C PF00043.25 EEQ33459.1 - 9.9e-17 60.9 0.3 3.8e-16 59.1 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EEQ33459.1 - 3.9e-13 49.5 0.0 8.3e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EEQ33459.1 - 6e-12 45.7 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ33459.1 - 4.8e-10 39.7 0.0 8.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ33459.1 - 9.9e-09 35.1 0.2 5.4e-08 32.7 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ33459.1 - 5.3e-08 33.0 0.1 9.5e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EEQ33459.1 - 0.018 15.6 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Polyhedrin PF00738.18 EEQ33459.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Polyhedrin Complex1_LYR PF05347.15 EEQ33460.1 - 1.5e-10 41.0 0.0 3.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) UQ_con PF00179.26 EEQ33461.1 - 1.6e-10 40.7 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEQ33461.1 - 0.014 15.7 0.0 0.014 15.7 0.0 1.1 1 0 0 1 1 1 0 RWD domain DCB PF16213.5 EEQ33462.1 - 2.9e-42 144.3 4.3 2.9e-42 144.3 4.3 3.4 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EEQ33462.1 - 1.1e-34 119.6 3.2 1.1e-34 119.6 3.2 5.2 4 2 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EEQ33462.1 - 4.4e-19 68.2 4.0 5.6e-19 67.8 2.6 1.8 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 EEQ33462.1 - 0.0029 17.4 2.5 0.068 13.0 0.0 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Gly_acyl_tr_N PF06021.11 EEQ33462.1 - 0.015 15.4 1.9 0.087 12.9 0.3 2.6 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Antimicrobial19 PF08225.11 EEQ33462.1 - 0.18 11.4 0.0 0.56 9.9 0.0 1.8 1 0 0 1 1 1 0 Pseudin antimicrobial peptide Vps26 PF03643.15 EEQ33463.1 - 5.9e-129 428.9 0.1 7e-129 428.7 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EEQ33463.1 - 0.00043 20.4 0.1 2.1 8.4 0.0 3.4 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain AAA_18 PF13238.6 EEQ33466.1 - 6.3e-11 42.9 0.0 2.7e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ33466.1 - 8.7e-11 42.2 0.1 2.6e-10 40.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain SKI PF01202.22 EEQ33466.1 - 1.4e-10 41.5 0.1 1.7e-09 38.0 0.1 2.1 1 1 0 1 1 1 1 Shikimate kinase Rad17 PF03215.15 EEQ33466.1 - 3.7e-07 30.2 0.0 6.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain dNK PF01712.19 EEQ33466.1 - 5.1e-06 26.5 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_17 PF13207.6 EEQ33466.1 - 1.2e-05 25.7 0.0 0.0058 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EEQ33466.1 - 9.4e-05 22.8 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 EEQ33466.1 - 0.00022 21.0 0.0 0.00054 19.8 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase AAA_16 PF13191.6 EEQ33466.1 - 0.00032 21.1 0.0 0.00039 20.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EEQ33466.1 - 0.00045 20.3 0.0 0.00096 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EEQ33466.1 - 0.0006 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EEQ33466.1 - 0.00082 19.7 0.0 0.0013 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEQ33466.1 - 0.0019 18.6 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Herpes_Helicase PF02689.14 EEQ33466.1 - 0.0044 15.0 0.0 0.006 14.6 0.0 1.1 1 0 0 1 1 1 1 Helicase AAA_28 PF13521.6 EEQ33466.1 - 0.0046 17.2 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EEQ33466.1 - 0.0048 16.2 0.0 0.026 13.8 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin Cytidylate_kin2 PF13189.6 EEQ33466.1 - 0.0055 16.9 0.1 0.053 13.7 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase-like family APS_kinase PF01583.20 EEQ33466.1 - 0.0068 16.3 0.0 0.031 14.2 0.0 1.9 1 1 0 1 1 1 1 Adenylylsulphate kinase PRK PF00485.18 EEQ33466.1 - 0.0099 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 EEQ33466.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE tRNA_lig_kinase PF08303.11 EEQ33466.1 - 0.016 15.3 0.0 0.04 14.0 0.0 1.7 2 0 0 2 2 1 0 tRNA ligase kinase domain RuvB_N PF05496.12 EEQ33466.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 EEQ33466.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EEQ33466.1 - 0.04 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EEQ33466.1 - 0.04 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EEQ33466.1 - 0.041 14.2 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EEQ33466.1 - 0.045 13.7 0.0 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 EEQ33466.1 - 0.046 13.0 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 EEQ33466.1 - 0.05 14.1 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 EEQ33466.1 - 0.05 13.4 0.1 0.06 13.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EEQ33466.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EEQ33466.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ADK PF00406.22 EEQ33466.1 - 0.1 12.7 0.1 2.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase AAA_7 PF12775.7 EEQ33466.1 - 0.1 12.1 0.0 0.5 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 EEQ33466.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain CoaE PF01121.20 EEQ33466.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase T2SSE PF00437.20 EEQ33466.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 EEQ33466.1 - 0.13 11.8 0.0 0.39 10.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 EEQ33466.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein PduV-EutP PF10662.9 EEQ33466.1 - 0.19 11.5 0.0 0.55 10.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NUDE_C PF04880.13 EEQ33466.1 - 4.4 7.7 7.8 5.5 7.4 4.6 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Acetyltransf_3 PF13302.7 EEQ33467.1 - 1.4e-16 61.4 0.0 1.6e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C14 PF00656.22 EEQ33468.1 - 2.6e-41 142.2 0.1 8e-39 134.1 0.1 2.2 1 1 0 1 1 1 1 Caspase domain 2-oxoacid_dh PF00198.23 EEQ33469.1 - 4.3e-79 265.2 0.3 5.6e-79 264.8 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 EEQ33469.1 - 1e-13 51.4 0.0 2.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 EEQ33469.1 - 1.2e-12 47.5 0.0 5e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme PI-PLC-X PF00388.19 EEQ33470.1 - 5.8e-10 38.9 0.0 9.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.20 EEQ33471.1 - 0.081 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L10 F-box PF00646.33 EEQ33472.1 - 0.08 12.8 0.3 0.08 12.8 0.3 1.9 2 0 0 2 2 2 0 F-box domain Glycos_transf_3 PF00591.21 EEQ33473.1 - 1.3e-55 188.7 0.0 8.3e-53 179.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EEQ33473.1 - 4.5e-06 26.4 0.7 4.5e-06 26.4 0.7 1.7 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.13 EEQ33474.1 - 2.2e-17 62.4 7.0 2.9e-17 62.0 7.0 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2318 PF10080.9 EEQ33474.1 - 0.0011 19.1 0.2 0.0011 19.0 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) HypA PF01155.19 EEQ33474.1 - 0.0017 18.3 0.3 0.0018 18.2 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2197 PF09963.9 EEQ33474.1 - 0.0039 17.4 2.6 0.19 12.0 0.2 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) zinc-ribbon_6 PF10005.9 EEQ33474.1 - 0.0052 17.4 0.5 0.0073 17.0 0.5 1.2 1 0 0 1 1 1 1 zinc-ribbon domain GFA PF04828.14 EEQ33474.1 - 0.0097 16.2 0.7 2.2 8.7 0.0 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 EEQ33474.1 - 0.012 15.6 0.3 0.016 15.2 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EEQ33474.1 - 0.015 15.4 0.7 0.027 14.6 0.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF1451 PF07295.11 EEQ33474.1 - 0.017 15.2 0.2 0.019 15.0 0.2 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain zinc-ribbons_6 PF07191.12 EEQ33474.1 - 0.018 15.0 0.3 0.024 14.6 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 EEQ33474.1 - 0.02 14.5 1.6 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF2757 PF10955.8 EEQ33474.1 - 0.037 14.3 0.6 0.046 14.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Zn_ribbon_SprT PF17283.2 EEQ33474.1 - 0.046 13.6 2.4 0.083 12.8 2.4 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Zn_ribbon_recom PF13408.6 EEQ33474.1 - 0.13 12.8 5.4 2.1 8.9 0.9 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF951 PF06107.11 EEQ33474.1 - 0.31 11.0 3.3 0.97 9.4 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) TFIIS_C PF01096.18 EEQ33474.1 - 0.92 9.4 4.9 7.5 6.5 0.7 2.5 1 1 0 2 2 2 0 Transcription factor S-II (TFIIS) fn3 PF00041.21 EEQ33475.1 - 1.4e-12 47.8 3.5 1.1e-07 32.1 0.0 3.7 3 1 1 4 4 4 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.6 EEQ33475.1 - 2.2e-12 47.7 0.1 1.6e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EEQ33475.1 - 0.0031 17.5 0.0 0.007 16.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4992 PF16383.5 EEQ33475.1 - 0.046 13.3 0.1 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function He_PIG PF05345.12 EEQ33475.1 - 0.72 10.1 3.8 0.6 10.3 0.4 2.5 3 0 0 3 3 3 0 Putative Ig domain Gastrin PF00918.17 EEQ33476.1 - 5.3 8.0 8.6 0.48 11.4 2.1 2.4 3 0 0 3 3 3 0 Gastrin/cholecystokinin family Fe_hyd_lg_C PF02906.14 EEQ33477.1 - 5.4e-51 173.6 0.0 1.1e-50 172.6 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain UbiA PF01040.18 EEQ33478.1 - 1e-19 70.9 12.3 1.3e-19 70.5 12.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2427 PF10348.9 EEQ33478.1 - 5 7.0 6.0 22 4.9 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) TatC PF00902.18 EEQ33478.1 - 6.1 6.6 8.2 32 4.3 5.5 2.8 1 1 0 2 2 2 0 Sec-independent protein translocase protein (TatC) DUF2263 PF10021.9 EEQ33479.1 - 9.2e-20 71.5 0.0 4.3e-19 69.3 0.0 2.1 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Fapy_DNA_glyco PF01149.24 EEQ33480.1 - 5.8e-35 120.4 0.1 1.4e-34 119.2 0.0 1.6 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EEQ33480.1 - 1.5e-20 72.9 0.0 3e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EEQ33480.1 - 0.0041 16.0 0.0 0.0098 14.7 0.0 1.5 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) XRCC4 PF06632.12 EEQ33480.1 - 2.2 7.1 8.0 3.5 6.4 8.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RR_TM4-6 PF06459.12 EEQ33480.1 - 3.4 7.4 6.6 5.5 6.7 6.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cid2 PF09774.9 EEQ33481.1 - 9e-56 188.7 0.1 1.1e-55 188.5 0.1 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.8 EEQ33482.1 - 4.6e-217 722.0 7.8 1.3e-216 720.5 1.8 2.3 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 EEQ33482.1 - 2.2e-23 80.9 16.4 0.00069 20.2 0.6 11.1 7 3 4 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ33482.1 - 1e-19 69.0 37.2 9.9e-05 22.2 0.5 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ33482.1 - 6.9e-18 64.9 29.5 0.00028 21.3 0.0 7.5 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ33482.1 - 1e-17 64.5 12.4 0.0021 18.7 0.4 8.5 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ33482.1 - 8.2e-12 45.3 16.9 0.0054 17.0 0.4 7.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ33482.1 - 8.2e-12 44.4 36.4 1.5e-05 24.6 0.6 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ33482.1 - 1.4e-11 44.4 14.3 0.00083 19.5 0.0 6.8 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ33482.1 - 3.7e-11 42.5 13.8 0.00041 20.0 1.4 6.4 6 0 0 6 6 6 3 TPR repeat ANAPC3 PF12895.7 EEQ33482.1 - 1e-08 35.3 14.5 0.00077 19.6 3.2 4.7 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EEQ33482.1 - 3.2e-08 33.4 15.9 0.065 13.6 0.0 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ33482.1 - 4.2e-08 32.8 34.4 0.00032 20.7 0.3 9.0 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 EEQ33482.1 - 3.8e-05 23.1 13.6 0.0056 15.9 2.6 3.9 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ33482.1 - 0.00012 22.5 20.9 0.1 13.3 0.1 7.5 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ33482.1 - 0.00031 20.2 8.1 0.83 9.0 0.2 4.0 2 1 2 4 4 4 3 MalT-like TPR region TPR_21 PF09976.9 EEQ33482.1 - 0.00041 20.1 15.8 0.001 18.8 0.2 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat-like domain BTAD PF03704.17 EEQ33482.1 - 0.002 18.6 5.1 0.012 16.1 0.5 3.4 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 EEQ33482.1 - 0.0034 17.9 7.1 5.6 7.9 0.1 5.0 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EEQ33482.1 - 0.0036 17.4 12.1 12 6.0 0.2 6.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EEQ33482.1 - 0.0038 17.2 14.7 1.2 9.3 0.1 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_3 PF07720.12 EEQ33482.1 - 0.0051 16.8 6.1 0.06 13.4 0.2 3.6 4 0 0 4 4 2 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 EEQ33482.1 - 0.0061 16.6 0.1 0.029 14.5 0.1 2.2 1 0 0 1 1 1 1 Rapsyn N-terminal myristoylation and linker region Prefoldin PF02996.17 EEQ33482.1 - 5.1 7.0 6.6 20 5.1 0.1 3.9 3 1 1 4 4 4 0 Prefoldin subunit TPR_10 PF13374.6 EEQ33482.1 - 6.4 6.8 21.6 9.2 6.3 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat Tim54 PF11711.8 EEQ33483.1 - 3.5e-139 463.8 0.0 4.4e-139 463.4 0.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 EEQ33484.1 - 3e-56 190.7 0.0 5.1e-55 186.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ33484.1 - 1.1e-24 87.2 0.3 5.4e-19 68.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ33484.1 - 4.6e-06 25.8 0.1 6.8e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EEQ33484.1 - 0.00073 18.9 0.2 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EEQ33484.1 - 0.0016 17.8 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ33484.1 - 0.003 17.5 4.9 0.039 13.9 0.2 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family NFACT-C PF11923.8 EEQ33484.1 - 0.038 13.9 0.4 0.081 12.8 0.4 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain Pkinase_fungal PF17667.1 EEQ33484.1 - 0.041 12.7 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EEQ33484.1 - 0.047 12.8 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PepX_N PF09168.10 EEQ33484.1 - 0.047 14.1 0.6 0.1 13.0 0.6 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Pox_ser-thr_kin PF05445.11 EEQ33484.1 - 0.076 12.0 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TFIIA PF03153.13 EEQ33484.1 - 0.24 11.4 17.8 0.41 10.6 17.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RIO1 PF01163.22 EEQ33484.1 - 0.36 10.4 2.5 0.85 9.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family SF3A2 PF16835.5 EEQ33485.1 - 4.6e-37 126.3 0.0 6.6e-37 125.8 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EEQ33485.1 - 1.2e-05 25.5 0.5 2.1e-05 24.8 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 EEQ33485.1 - 0.05 13.2 1.5 0.11 12.0 1.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like p450 PF00067.22 EEQ33486.1 - 6.6e-63 213.1 0.0 8.6e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.6 EEQ33487.1 - 2.7e-37 126.9 29.2 1.5e-12 47.6 1.1 7.3 2 1 7 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ33487.1 - 8.9e-28 95.4 15.0 2.3e-05 24.1 0.0 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat Helo_like_N PF17111.5 EEQ33487.1 - 2e-10 40.4 2.9 6e-10 38.8 1.1 2.5 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins TPR_MalT PF17874.1 EEQ33487.1 - 2.7e-08 33.6 7.4 0.085 12.2 2.7 3.1 1 1 0 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 EEQ33487.1 - 1.6e-07 31.7 8.3 0.2 12.2 0.3 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ33487.1 - 5.8e-07 30.1 8.2 0.16 12.7 0.7 6.9 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ33487.1 - 6.2e-06 25.8 0.9 0.34 10.8 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ33487.1 - 2.7e-05 23.9 9.0 6.8 7.0 0.0 6.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ33487.1 - 4.6e-05 23.3 3.6 3.6 8.0 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ33487.1 - 4.8e-05 23.1 12.9 2.6 8.4 0.0 6.7 8 0 0 8 8 7 1 Tetratricopeptide repeat PSY3 PF16836.5 EEQ33487.1 - 0.0011 18.5 0.3 0.0047 16.5 0.1 2.1 2 0 0 2 2 2 1 Shu complex component Psy3, DNA-binding description DUF3427 PF11907.8 EEQ33487.1 - 0.0035 16.7 1.2 0.0086 15.4 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3427) TPR_4 PF07721.14 EEQ33487.1 - 0.0043 17.5 19.9 0.21 12.3 0.6 5.9 6 0 0 6 6 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ33487.1 - 0.0074 16.5 0.2 9.5 6.5 0.0 3.9 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.22 EEQ33487.1 - 0.011 15.0 0.0 0.031 13.5 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain SPO22 PF08631.10 EEQ33487.1 - 0.012 15.1 0.4 0.097 12.1 0.4 2.6 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like ATPase_2 PF01637.18 EEQ33487.1 - 0.019 14.9 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EEQ33487.1 - 0.023 14.6 0.0 0.08 12.9 0.0 2.0 2 0 0 2 2 1 0 NACHT domain AAA_24 PF13479.6 EEQ33487.1 - 0.079 12.7 0.3 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain TPR_14 PF13428.6 EEQ33487.1 - 0.089 13.7 16.0 4.9 8.3 0.2 7.1 6 2 2 8 8 7 0 Tetratricopeptide repeat DUF1664 PF07889.12 EEQ33487.1 - 0.09 12.8 11.9 7.2 6.7 0.2 4.6 4 1 1 5 5 4 0 Protein of unknown function (DUF1664) TPR_17 PF13431.6 EEQ33487.1 - 0.17 12.3 3.9 73 4.1 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 EEQ33487.1 - 1.3 9.3 3.6 4.1 7.7 0.1 3.3 4 0 0 4 4 3 0 Tetratrico peptide repeat TPR_6 PF13174.6 EEQ33487.1 - 5.9 7.8 12.3 35 5.3 0.0 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Ank_2 PF12796.7 EEQ33488.1 - 3.2e-77 255.2 2.8 1.4e-14 54.5 0.2 11.0 4 3 6 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ33488.1 - 1e-72 239.6 20.9 6.4e-09 36.2 0.2 16.0 8 4 10 18 18 18 16 Ankyrin repeats (many copies) Ank PF00023.30 EEQ33488.1 - 1.2e-52 174.1 23.4 0.00011 22.4 0.1 18.5 20 0 0 20 20 20 12 Ankyrin repeat Ank_3 PF13606.6 EEQ33488.1 - 2.1e-52 168.9 17.9 0.0075 16.7 0.0 20.9 22 0 0 22 22 22 10 Ankyrin repeat Ank_5 PF13857.6 EEQ33488.1 - 3.4e-52 173.8 17.6 3.8e-09 36.6 0.1 14.8 10 3 7 17 17 17 13 Ankyrin repeats (many copies) F-box-like PF12937.7 EEQ33488.1 - 0.03 14.2 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like A2L_zn_ribbon PF08792.10 EEQ33489.1 - 0.0063 16.2 1.5 0.4 10.5 0.4 2.4 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-dskA_traR PF01258.17 EEQ33489.1 - 0.13 12.2 2.9 2.6 8.1 0.4 2.8 2 1 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger LRR_4 PF12799.7 EEQ33490.1 - 1e-05 25.8 14.9 0.24 11.9 0.0 4.8 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EEQ33490.1 - 0.013 15.5 2.1 33 4.9 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat Trnau1ap PF17654.1 EEQ33490.1 - 0.026 15.4 1.9 0.034 15.0 0.2 2.1 2 0 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins LRR_8 PF13855.6 EEQ33490.1 - 0.044 13.6 13.2 0.24 11.2 1.3 3.9 2 1 3 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 EEQ33490.1 - 0.061 13.9 9.0 38 5.4 1.2 4.9 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_9 PF14580.6 EEQ33490.1 - 0.072 12.6 2.1 0.23 11.0 0.3 2.4 2 1 0 2 2 2 0 Leucine-rich repeat Zn_clus PF00172.18 EEQ33491.1 - 1.4e-08 34.7 10.4 2.4e-08 34.0 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 EEQ33492.1 - 3e-56 189.6 0.0 4e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ33492.1 - 2.3e-13 49.9 0.0 2.7e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EEQ33492.1 - 6e-05 23.3 0.2 9.2e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EEQ33492.1 - 0.068 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain CwfJ_C_1 PF04677.15 EEQ33493.1 - 1.5e-30 105.6 0.0 3.8e-30 104.2 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EEQ33493.1 - 9.6e-28 97.0 0.0 9.6e-28 97.0 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.9 EEQ33493.1 - 0.0053 17.2 2.9 1.5 9.3 0.1 3.0 3 0 0 3 3 3 2 Fumarase C C-terminus ATP_bind_1 PF03029.17 EEQ33494.1 - 7.4e-71 238.7 0.0 1.1e-70 238.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EEQ33494.1 - 6.1e-05 22.6 0.0 0.0049 16.4 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EEQ33494.1 - 0.00012 21.1 0.0 0.023 13.7 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EEQ33494.1 - 0.00089 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EEQ33494.1 - 0.0014 18.7 0.0 0.018 15.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 EEQ33494.1 - 0.0026 17.4 0.0 0.033 13.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PRK PF00485.18 EEQ33494.1 - 0.0027 17.5 0.0 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 EEQ33494.1 - 0.0031 17.1 0.0 0.087 12.4 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B Roc PF08477.13 EEQ33494.1 - 0.0042 17.3 0.0 0.88 9.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EEQ33494.1 - 0.0046 16.9 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 1 1 NACHT domain G-alpha PF00503.20 EEQ33494.1 - 0.0081 15.4 0.2 0.31 10.1 0.0 2.5 2 1 0 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 EEQ33494.1 - 0.0089 15.9 0.0 3.2 7.6 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase cobW PF02492.19 EEQ33494.1 - 0.009 15.6 0.0 1.9 8.0 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EEQ33494.1 - 0.011 14.9 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Arf PF00025.21 EEQ33494.1 - 0.012 15.0 0.0 2.3 7.6 0.0 3.0 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_16 PF13191.6 EEQ33494.1 - 0.013 15.8 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EEQ33494.1 - 0.02 15.2 0.0 0.054 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EEQ33494.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EEQ33494.1 - 0.027 14.3 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 EEQ33494.1 - 0.03 13.9 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EEQ33494.1 - 0.03 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EEQ33494.1 - 0.036 14.6 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0240 PF06784.11 EEQ33494.1 - 0.12 12.4 1.5 0.23 11.5 1.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) PduV-EutP PF10662.9 EEQ33494.1 - 0.19 11.5 0.1 1.3 8.8 0.0 2.3 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GST_N_3 PF13417.6 EEQ33496.1 - 1.7e-19 70.0 0.0 3.4e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EEQ33496.1 - 9.7e-15 54.6 0.0 2.6e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EEQ33496.1 - 6.4e-07 29.6 0.0 1.4e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ33496.1 - 2e-06 27.7 0.1 4.5e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ33496.1 - 0.027 14.7 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EEQ33496.1 - 0.029 14.9 0.0 0.057 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SUZ PF12752.7 EEQ33497.1 - 9.8e-05 23.0 5.8 9.8e-05 23.0 5.8 3.8 3 1 0 3 3 3 1 SUZ domain DUF1481 PF07356.12 EEQ33499.1 - 0.28 10.9 1.3 4.8 6.9 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1481) AAA_12 PF13087.6 EEQ33500.1 - 2.1e-41 141.7 0.8 4.8e-41 140.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EEQ33500.1 - 2.3e-41 141.3 0.0 2.2e-12 47.5 0.0 5.3 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EEQ33500.1 - 1.3e-24 87.4 42.3 1.2e-22 81.0 0.0 7.2 5 2 0 6 6 5 2 AAA domain AAA_30 PF13604.6 EEQ33500.1 - 6.5e-23 81.5 0.9 0.00043 20.1 0.0 6.6 6 0 0 6 6 6 5 AAA domain AAA_19 PF13245.6 EEQ33500.1 - 4.8e-19 69.1 0.1 4.5e-08 33.5 0.0 6.0 5 2 1 6 6 4 2 AAA domain AAA_lid_6 PF17866.1 EEQ33500.1 - 5.6e-17 61.7 0.6 1.5e-06 28.3 0.5 4.3 3 0 0 3 3 3 2 AAA lid domain AAA_5 PF07728.14 EEQ33500.1 - 4.1e-14 52.7 0.4 0.0071 16.3 0.0 4.8 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ33500.1 - 9.8e-11 42.1 10.3 0.082 13.2 0.1 7.8 5 3 0 5 5 4 3 AAA domain Mg_chelatase PF01078.21 EEQ33500.1 - 1.7e-10 40.7 0.4 0.093 12.1 0.0 4.8 5 0 0 5 5 4 3 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EEQ33500.1 - 8.9e-10 38.5 0.5 0.25 11.1 0.0 4.8 4 1 0 4 4 4 3 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EEQ33500.1 - 2.3e-09 37.4 0.1 0.028 14.1 0.0 6.0 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EEQ33500.1 - 3e-08 33.6 0.1 0.19 11.5 0.0 4.8 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EEQ33500.1 - 7.5e-08 32.7 0.2 3.1 8.2 0.0 5.0 4 0 0 4 4 4 1 RNA helicase AAA_16 PF13191.6 EEQ33500.1 - 5.9e-07 30.0 14.9 0.1 13.0 0.0 5.8 6 0 0 6 6 4 3 AAA ATPase domain AAA_7 PF12775.7 EEQ33500.1 - 2.1e-06 27.4 0.4 3.3 7.2 0.0 4.5 4 0 0 4 4 4 1 P-loop containing dynein motor region ResIII PF04851.15 EEQ33500.1 - 2e-05 24.7 14.5 0.00034 20.7 0.0 6.4 6 1 0 7 7 6 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 EEQ33500.1 - 2.6e-05 24.0 6.0 2.4 7.9 0.1 5.1 5 0 0 5 5 5 2 AAA domain Sigma54_activat PF00158.26 EEQ33500.1 - 7.9e-05 22.4 0.3 10 5.8 0.0 4.8 5 0 0 5 5 5 0 Sigma-54 interaction domain Torsin PF06309.11 EEQ33500.1 - 0.00022 21.3 0.0 18 5.4 0.0 4.3 4 0 0 4 4 4 0 Torsin AAA_18 PF13238.6 EEQ33500.1 - 0.00049 20.7 17.8 0.88 10.1 0.0 6.2 6 1 0 6 6 4 1 AAA domain DUF2075 PF09848.9 EEQ33500.1 - 0.0014 17.9 19.5 0.0084 15.4 0.0 7.6 8 2 1 9 9 8 1 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 EEQ33500.1 - 0.0018 18.3 0.1 0.2 11.7 0.0 3.6 4 0 0 4 4 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 EEQ33500.1 - 0.0019 18.1 2.6 11 5.9 0.0 4.2 4 0 0 4 4 4 0 NACHT domain AAA_25 PF13481.6 EEQ33500.1 - 0.0068 16.0 1.3 15 5.1 0.0 4.7 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 EEQ33500.1 - 0.007 16.4 0.6 2.9 7.9 0.1 3.8 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 EEQ33500.1 - 0.052 12.5 0.1 34 3.2 0.0 4.1 5 0 0 5 5 5 0 Hydrolytic ATP binding site of dynein motor region Adeno_IVa2 PF02456.15 EEQ33500.1 - 0.056 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_33 PF13671.6 EEQ33500.1 - 0.14 12.3 25.1 0.28 11.3 0.0 6.1 7 0 0 7 7 4 0 AAA domain NTPase_1 PF03266.15 EEQ33500.1 - 0.17 11.8 7.0 6.6 6.6 0.1 4.8 5 0 0 5 5 4 0 NTPase ADK PF00406.22 EEQ33500.1 - 0.23 11.5 1.7 15 5.7 0.1 3.7 3 0 0 3 3 3 0 Adenylate kinase SRP54 PF00448.22 EEQ33500.1 - 0.31 10.6 1.6 9.8 5.7 0.0 3.6 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EEQ33500.1 - 6.2 6.1 16.0 4.3 6.6 0.0 4.7 6 0 0 6 6 5 0 KaiC LRR_6 PF13516.6 EEQ33503.1 - 7.3e-06 25.6 5.9 3.3 8.0 0.0 6.1 5 0 0 5 5 5 2 Leucine Rich repeat F-box-like PF12937.7 EEQ33503.1 - 1.6e-05 24.7 0.2 4.8e-05 23.2 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EEQ33503.1 - 0.00064 20.1 15.2 0.26 11.8 0.2 5.8 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EEQ33503.1 - 0.0058 17.0 7.2 42 5.3 0.1 6.7 6 0 0 6 6 6 0 Leucine Rich Repeat F-box PF00646.33 EEQ33503.1 - 0.042 13.8 1.8 0.42 10.5 1.4 2.9 2 1 0 2 2 2 0 F-box domain DUF3488 PF11992.8 EEQ33504.1 - 0.64 8.9 3.7 0.37 9.7 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3488) AA_permease_2 PF13520.6 EEQ33505.1 - 8.3e-60 202.8 48.9 9.8e-60 202.5 48.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ33505.1 - 7.3e-25 87.5 42.3 9.7e-25 87.1 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 EEQ33506.1 - 1.3e-47 162.6 0.0 6e-47 160.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ZNRF_3_ecto PF18212.1 EEQ33507.1 - 0.0044 17.0 0.1 0.17 11.9 0.1 2.3 2 0 0 2 2 2 2 ZNRF-3 Ectodomain TFIIS_C PF01096.18 EEQ33508.1 - 5.2e-18 64.6 10.5 5.7e-18 64.5 2.6 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 EEQ33508.1 - 3e-05 24.0 6.3 0.044 13.9 0.2 3.2 3 0 0 3 3 3 2 Zinc ribbon domain DZR PF12773.7 EEQ33508.1 - 0.00027 20.9 7.8 0.016 15.2 0.4 2.7 2 1 0 2 2 2 2 Double zinc ribbon Baculo_LEF5_C PF11792.8 EEQ33508.1 - 0.00044 19.9 0.6 0.00044 19.9 0.6 3.3 3 1 1 4 4 4 1 Baculoviridae late expression factor 5 C-terminal domain C1_1 PF00130.22 EEQ33508.1 - 0.00099 18.9 6.9 0.0014 18.5 0.3 2.6 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.6 EEQ33508.1 - 0.0015 17.8 8.5 1 8.9 0.1 3.9 3 1 1 4 4 4 2 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EEQ33508.1 - 0.0042 16.9 9.7 4.5 7.2 0.2 3.5 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit tRNA-synt_1f PF01921.18 EEQ33508.1 - 0.023 13.6 0.3 0.024 13.5 0.3 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) HypA PF01155.19 EEQ33508.1 - 0.031 14.3 8.4 0.64 10.1 2.3 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 EEQ33508.1 - 0.048 13.6 12.7 0.059 13.3 0.3 4.0 4 1 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 EEQ33508.1 - 0.05 13.3 6.3 0.44 10.3 1.5 2.9 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein OrfB_Zn_ribbon PF07282.11 EEQ33508.1 - 0.11 12.4 10.7 0.27 11.2 0.3 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.6 EEQ33508.1 - 0.37 10.8 6.7 11 6.1 0.0 3.7 4 0 0 4 4 4 0 Nudix N-terminal zf-C2HC5 PF06221.13 EEQ33508.1 - 0.48 10.4 4.7 0.6 10.1 0.4 2.7 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type DUF4379 PF14311.6 EEQ33508.1 - 0.55 10.6 8.7 0.48 10.8 2.6 2.7 2 1 1 3 3 3 0 Probable Zinc-ribbon domain eIF-5_eIF-2B PF01873.17 EEQ33508.1 - 0.55 10.1 7.3 0.88 9.5 1.4 2.6 2 1 1 3 3 3 0 Domain found in IF2B/IF5 Ribosomal_S27e PF01667.17 EEQ33508.1 - 0.7 9.6 11.3 5.7 6.7 2.1 3.5 2 2 0 2 2 2 0 Ribosomal protein S27 DUF35_N PF12172.8 EEQ33508.1 - 0.77 9.7 5.8 1.6 8.7 0.1 3.5 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RPA_interact_C PF14768.6 EEQ33508.1 - 0.95 10.1 8.6 5.7 7.6 8.6 2.3 1 1 0 1 1 1 0 Replication protein A interacting C-terminal zf_UBZ PF18439.1 EEQ33508.1 - 1.1 8.9 10.9 14 5.4 0.3 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Rubredoxin_2 PF18073.1 EEQ33508.1 - 1.1 9.0 13.9 0.89 9.3 0.8 4.0 4 0 0 4 4 4 0 Rubredoxin metal binding domain TF_Zn_Ribbon PF08271.12 EEQ33508.1 - 1.8 8.2 9.1 2.2 7.9 0.2 3.4 2 2 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 EEQ33508.1 - 1.8 8.4 11.9 2 8.3 0.2 3.8 3 1 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 EEQ33508.1 - 2.7 7.8 6.7 16 5.3 0.1 3.3 3 0 0 3 3 3 0 InsA N-terminal domain DNA_RNApol_7kD PF03604.13 EEQ33508.1 - 3.7 7.3 9.0 2.8 7.7 0.1 3.4 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_3 PF13878.6 EEQ33508.1 - 4.2 7.3 11.7 20 5.1 0.1 4.0 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO HalOD2 PF18547.1 EEQ33508.1 - 7.9 6.5 11.7 10 6.1 1.4 3.2 2 2 0 2 2 2 0 Halobacterial output domain 2 BSD PF03909.17 EEQ33509.1 - 1.2e-23 82.8 9.5 1.2e-11 44.5 1.0 3.1 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 EEQ33509.1 - 8.1e-23 80.6 0.0 1.9e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Spore_III_AB PF09548.10 EEQ33509.1 - 0.019 15.1 0.1 0.057 13.5 0.1 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Activator-TraM PF11657.8 EEQ33509.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.8 3 0 0 3 3 3 0 Transcriptional activator TraM PIN_8 PF18476.1 EEQ33509.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.8 3 0 0 3 3 3 0 PIN like domain DUF1751 PF08551.10 EEQ33510.1 - 0.006 17.1 2.0 0.0076 16.8 0.8 1.9 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DUF2070 PF09843.9 EEQ33510.1 - 5.9 5.1 14.3 7.8 4.7 14.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ING PF12998.7 EEQ33511.1 - 2.1e-10 41.1 0.0 4.6e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EEQ33511.1 - 2.6e-06 27.2 6.9 4.2e-06 26.6 6.9 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEQ33511.1 - 0.05 13.2 2.6 0.085 12.4 2.6 1.4 1 0 0 1 1 1 0 PHD-finger DUF4504 PF14953.6 EEQ33511.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) zf-HC5HC2H PF13771.6 EEQ33511.1 - 0.14 12.4 1.7 0.3 11.4 1.7 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Transket_pyr PF02779.24 EEQ33512.1 - 5.6e-66 221.6 0.0 9.6e-66 220.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EEQ33512.1 - 4.6e-57 192.0 0.1 8.1e-57 191.2 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EEQ33512.1 - 2e-56 191.2 0.0 3e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 EEQ33512.1 - 3.1e-20 71.5 0.6 3.1e-20 71.5 0.6 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus SHR-BD PF06650.12 EEQ33513.1 - 5e-93 311.4 0.1 7.1e-92 307.6 0.0 3.0 4 1 0 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EEQ33513.1 - 9.9e-92 306.6 14.1 5.2e-88 294.4 1.2 6.0 6 0 0 6 6 6 2 Repeating coiled region of VPS13 VPS13 PF16908.5 EEQ33513.1 - 8e-80 268.0 4.7 1.1e-78 264.3 0.0 4.3 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EEQ33513.1 - 9.3e-73 243.8 9.9 3.9e-70 235.2 0.3 3.1 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EEQ33513.1 - 9.3e-41 138.6 0.2 3.3e-40 136.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EEQ33513.1 - 7.4e-06 26.2 0.0 2.4e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF896 PF05979.12 EEQ33513.1 - 0.41 10.6 3.3 0.32 10.9 0.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF3429 PF11911.8 EEQ33515.1 - 8e-45 152.7 12.6 1.2e-44 152.1 12.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Nucleo_LEF-12 PF06256.11 EEQ33515.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein FGGY_C PF02782.16 EEQ33516.1 - 4.8e-71 238.6 0.3 1.3e-70 237.2 0.2 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EEQ33516.1 - 2.7e-57 194.2 0.0 3.6e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EEQ33516.1 - 0.18 11.3 0.5 0.63 9.5 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.18 EEQ33519.1 - 1.7e-55 187.8 0.1 3e-55 187.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EEQ33519.1 - 1.2e-42 145.4 0.0 2.6e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ33519.1 - 9.2e-10 38.2 0.0 2.6e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EEQ33519.1 - 1.6e-05 25.3 0.1 0.00026 21.4 0.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EEQ33519.1 - 4.9e-05 23.3 0.0 0.00015 21.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EEQ33519.1 - 5.1e-05 22.6 0.1 0.00013 21.3 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 EEQ33519.1 - 0.00013 22.2 1.1 0.014 15.7 0.3 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EEQ33519.1 - 0.00089 19.0 0.0 0.0025 17.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EEQ33519.1 - 0.0021 18.2 0.1 0.015 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EEQ33519.1 - 0.0025 18.0 0.0 0.0087 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EEQ33519.1 - 0.0091 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EEQ33519.1 - 0.016 15.7 0.0 0.051 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 EEQ33519.1 - 0.023 14.1 0.3 0.044 13.2 0.3 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EEQ33519.1 - 0.037 13.2 0.0 0.088 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 EEQ33519.1 - 0.039 13.3 0.0 1.4 8.2 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 EEQ33519.1 - 0.042 13.4 1.4 0.9 9.1 0.3 2.4 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EEQ33519.1 - 0.066 13.5 0.3 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EEQ33519.1 - 0.071 13.0 0.3 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 EEQ33519.1 - 0.091 13.2 0.1 0.46 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EEQ33519.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EEQ33519.1 - 0.11 12.5 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EEQ33519.1 - 0.17 11.1 0.8 0.62 9.3 0.4 2.1 1 1 1 2 2 2 0 Zeta toxin NTP_transferase PF00483.23 EEQ33521.1 - 8e-52 176.3 0.0 1.4e-51 175.5 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EEQ33521.1 - 1.6e-15 56.1 9.8 1.2e-10 40.7 3.0 4.0 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EEQ33521.1 - 2.4e-09 37.7 0.0 3.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EEQ33521.1 - 2e-06 27.4 1.3 2e-06 27.4 1.3 3.5 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EEQ33521.1 - 0.0034 15.6 0.1 0.0069 14.6 0.1 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) IspD PF01128.19 EEQ33521.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Shisa PF13908.6 EEQ33522.1 - 0.0096 16.2 0.4 0.011 16.0 0.4 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LAT PF15234.6 EEQ33522.1 - 0.0098 15.6 4.5 0.045 13.5 1.5 2.1 2 0 0 2 2 2 1 Linker for activation of T-cells Mid2 PF04478.12 EEQ33522.1 - 0.033 14.0 1.2 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF3328 PF11807.8 EEQ33522.1 - 0.058 13.2 0.1 0.084 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) HRG PF16954.5 EEQ33522.1 - 0.091 13.2 0.3 0.16 12.4 0.3 1.5 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Fic PF02661.18 EEQ33524.1 - 6.9e-10 39.7 0.9 1.5e-09 38.6 0.9 1.6 1 0 0 1 1 1 1 Fic/DOC family zf-C2H2 PF00096.26 EEQ33525.1 - 5.7e-17 61.1 38.3 0.00015 22.0 1.4 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ33525.1 - 2.1e-13 50.0 33.2 7e-06 26.2 0.5 5.6 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ33525.1 - 3.6e-05 24.2 34.9 0.2 12.6 2.9 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger Hydin_ADK PF17213.3 EEQ33525.1 - 0.57 10.4 6.7 0.95 9.7 6.7 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain FOXP-CC PF16159.5 EEQ33525.1 - 0.62 10.7 30.7 5.3 7.8 0.5 5.4 2 2 2 5 5 5 0 FOXP coiled-coil domain Suc_Fer-like PF06999.12 EEQ33526.1 - 2.7e-70 236.2 0.0 3.4e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like NICE-3 PF07406.11 EEQ33527.1 - 0.00062 19.8 0.1 0.0028 17.6 0.0 2.1 3 0 0 3 3 3 1 NICE-3 protein DUF4129 PF13559.6 EEQ33527.1 - 0.021 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) DUF4389 PF14333.6 EEQ33527.1 - 0.14 12.1 3.2 0.3 11.0 2.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4389) GCFC PF07842.12 EEQ33528.1 - 9.2e-86 287.9 8.4 1.6e-85 287.1 8.4 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EEQ33528.1 - 5.4e-16 58.2 0.5 9.8e-16 57.4 0.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EEQ33528.1 - 1e-06 28.7 0.3 1e-06 28.7 0.3 2.1 2 0 0 2 2 2 1 G-patch domain Sod_Fe_C PF02777.18 EEQ33529.1 - 1.1e-35 121.8 0.2 2e-35 121.0 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EEQ33529.1 - 5.4e-30 103.7 1.0 8.5e-30 103.1 1.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cnn_1N PF07989.11 EEQ33530.1 - 2.5e-06 27.6 14.6 8.5e-06 25.8 14.6 1.9 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 EEQ33530.1 - 0.029 14.5 15.5 0.052 13.7 15.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 EEQ33530.1 - 0.14 12.8 8.1 0.37 11.5 8.1 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 EEQ33530.1 - 0.67 9.5 7.8 1.2 8.6 7.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 EEQ33530.1 - 0.81 7.6 5.9 1.2 7.0 5.9 1.2 1 0 0 1 1 1 0 Prominin AAA_23 PF13476.6 EEQ33530.1 - 0.9 10.0 12.5 1.7 9.1 12.5 1.4 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 EEQ33530.1 - 4.5 7.5 9.1 9.9 6.3 9.1 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 EEQ33530.1 - 5.4 4.4 21.1 7.5 3.9 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LMBR1 PF04791.16 EEQ33530.1 - 7.2 5.4 9.7 6.3 5.6 8.5 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Sld5 PF05916.11 EEQ33531.1 - 1.5e-20 73.6 0.0 2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein NOA36 PF06524.12 EEQ33532.1 - 1.3 8.3 10.7 2.7 7.2 10.7 1.5 1 0 0 1 1 1 0 NOA36 protein CDC24 PF06395.11 EEQ33536.1 - 7.9e-35 119.0 0.0 1.5e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 EEQ33536.1 - 8.2e-34 116.5 0.2 6.7e-30 103.9 0.1 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain RhoGEF PF00621.20 EEQ33536.1 - 4.9e-26 92.1 0.9 9.2e-26 91.2 0.9 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EEQ33536.1 - 7.1e-08 32.3 0.0 1.7e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.32 EEQ33537.1 - 5.6e-28 96.6 12.7 0.00015 22.4 0.1 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 EEQ33537.1 - 1.4e-11 44.0 0.2 3e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ33537.1 - 1.2e-07 31.4 0.0 2.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EEQ33537.1 - 4.1e-06 27.0 0.7 0.55 10.6 0.0 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EEQ33537.1 - 0.0005 20.1 0.2 5.5 7.1 0.0 4.1 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EEQ33537.1 - 0.0079 15.5 0.2 3.3 6.9 0.0 2.9 2 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 EEQ33537.1 - 0.074 11.7 1.0 2.2 6.8 0.1 2.5 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Uds1 PF15456.6 EEQ33539.1 - 7.6e-38 129.6 2.7 7.6e-38 129.6 2.7 6.2 5 2 1 6 6 6 1 Up-regulated During Septation TPR_MLP1_2 PF07926.12 EEQ33539.1 - 0.026 14.6 0.6 0.026 14.6 0.6 8.3 7 1 1 9 9 9 0 TPR/MLP1/MLP2-like protein PilO PF04350.13 EEQ33539.1 - 0.24 11.6 0.0 0.24 11.6 0.0 4.7 5 1 1 6 6 6 0 Pilus assembly protein, PilO SPACA9 PF15120.6 EEQ33539.1 - 3.8 7.2 17.0 1.4 8.7 1.9 3.4 3 0 0 3 3 3 0 Sperm acrosome-associated protein 9 Baculo_PEP_C PF04513.12 EEQ33539.1 - 9.2 6.3 21.6 0.78 9.8 2.1 5.3 2 2 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.16 EEQ33540.1 - 7.2e-27 94.2 33.9 1.1e-26 93.7 33.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EEQ33540.1 - 4.5 6.0 18.1 0.25 10.2 1.8 3.5 1 1 2 4 4 4 0 MFS_1 like family UCR_hinge PF02320.16 EEQ33541.1 - 1.2e-26 92.7 6.2 1.2e-26 92.7 6.2 1.6 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein DUF4211 PF13926.6 EEQ33541.1 - 0.0086 16.1 1.6 0.011 15.7 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Sigma70_ner PF04546.13 EEQ33541.1 - 0.016 15.1 6.0 0.015 15.2 6.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region ORC_WH_C PF18137.1 EEQ33541.1 - 0.046 13.8 3.4 0.066 13.3 3.4 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal FAM176 PF14851.6 EEQ33541.1 - 0.19 11.4 4.9 0.25 11.0 4.9 1.4 1 0 0 1 1 1 0 FAM176 family DUF4045 PF13254.6 EEQ33541.1 - 0.24 11.0 6.4 0.3 10.7 6.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SDA1 PF05285.12 EEQ33541.1 - 0.34 10.3 10.5 0.34 10.3 10.5 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 EEQ33541.1 - 0.35 10.2 10.0 0.42 9.9 10.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 EEQ33541.1 - 0.43 9.9 9.3 0.47 9.8 9.3 1.0 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.8 EEQ33541.1 - 0.52 9.0 5.9 0.59 8.9 5.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.16 EEQ33541.1 - 0.54 9.4 6.5 0.58 9.3 6.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.11 EEQ33541.1 - 0.56 8.7 4.5 0.61 8.6 4.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3530 PF12048.8 EEQ33541.1 - 0.74 9.2 3.4 0.81 9.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DNA_pol_phi PF04931.13 EEQ33541.1 - 0.82 7.7 15.0 0.85 7.7 15.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EEQ33541.1 - 0.9 7.7 11.7 0.91 7.7 11.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 EEQ33541.1 - 1.3 8.4 4.6 1.4 8.2 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) HSP90 PF00183.18 EEQ33541.1 - 1.8 7.4 8.6 2.2 7.1 8.6 1.1 1 0 0 1 1 1 0 Hsp90 protein Radial_spoke PF04712.12 EEQ33541.1 - 2 7.3 12.2 2.3 7.1 12.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Roughex PF06020.11 EEQ33541.1 - 2.3 7.2 9.2 2.7 7.0 9.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2457 PF10446.9 EEQ33541.1 - 2.4 7.2 15.1 2.9 7.0 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 EEQ33541.1 - 5.6 5.1 9.3 5.9 5.1 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Cytomega_UL84 PF06284.11 EEQ33541.1 - 6.1 5.2 8.4 6.8 5.0 8.4 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Vps36_ESCRT-II PF11605.8 EEQ33542.1 - 0.00041 20.5 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Acyltransferase PF01553.21 EEQ33544.1 - 6.6e-10 38.7 0.0 0.00039 20.1 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase Prenyltransf PF01255.19 EEQ33545.1 - 5.4e-83 277.9 0.0 1.3e-82 276.7 0.0 1.6 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Sacchrp_dh_C PF16653.5 EEQ33546.1 - 2.8e-86 289.9 0.0 9.3e-86 288.2 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EEQ33546.1 - 6.2e-23 81.5 0.7 1.1e-22 80.7 0.7 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EEQ33546.1 - 1.5e-06 28.3 0.2 3e-06 27.4 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EEQ33546.1 - 0.0004 20.3 1.1 0.0077 16.1 0.2 2.1 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_7 PF13241.6 EEQ33546.1 - 0.038 14.4 0.1 0.087 13.3 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3Beta_HSD PF01073.19 EEQ33546.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N_2 PF13602.6 EEQ33547.1 - 8.5e-25 88.3 0.0 1.4e-24 87.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EEQ33547.1 - 2.3e-14 53.5 0.2 3.5e-14 52.9 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_15 PF00723.21 EEQ33548.1 - 4.4e-92 309.2 0.1 5.4e-92 308.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EEQ33548.1 - 9.5e-28 96.0 0.0 1.8e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Aha1_N PF09229.11 EEQ33549.1 - 3.7e-38 130.8 1.6 3.7e-38 130.8 1.6 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EEQ33549.1 - 2e-19 70.0 0.2 4e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.17 EEQ33549.1 - 0.58 10.2 19.0 1 9.4 19.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein FBPase PF00316.20 EEQ33551.1 - 1.5e-64 217.0 0.1 2e-64 216.6 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain OAD_gamma PF04277.13 EEQ33552.1 - 0.0046 17.5 0.3 0.017 15.7 0.1 1.9 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain ECSCR PF15820.5 EEQ33552.1 - 0.054 13.3 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Orf78 PF06024.12 EEQ33552.1 - 0.068 13.5 0.9 0.12 12.7 0.9 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 EEQ33552.1 - 0.46 10.7 7.2 3.4 7.9 7.2 2.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Fungal_trans_2 PF11951.8 EEQ33553.1 - 3.7e-38 131.4 2.8 4.7e-38 131.0 2.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ33553.1 - 2.3e-07 30.8 11.1 3.6e-07 30.2 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob_synth_C PF06463.13 EEQ33553.1 - 0.87 9.5 4.6 6.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C E1-E2_ATPase PF00122.20 EEQ33554.1 - 9.8e-38 129.5 13.1 6.7e-30 103.9 0.0 3.7 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 EEQ33554.1 - 1.7e-19 71.0 0.0 8.6e-15 55.6 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ33554.1 - 1.3e-16 60.4 0.0 3.3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 EEQ33554.1 - 1.8e-12 47.4 0.3 1.8e-12 47.4 0.3 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EEQ33554.1 - 3.7e-12 45.7 0.0 9.4e-12 44.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEQ33554.1 - 0.00031 20.6 0.8 0.0051 16.6 1.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HlyIII PF03006.20 EEQ33555.1 - 2.1e-21 76.7 9.5 3.5e-21 75.9 9.5 1.4 1 1 0 1 1 1 1 Haemolysin-III related DUF308 PF03729.13 EEQ33555.1 - 1.3 9.4 8.6 0.18 12.2 1.3 2.6 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Sugar_tr PF00083.24 EEQ33556.1 - 1e-83 281.8 26.8 1.2e-83 281.5 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ33556.1 - 1.9e-23 83.0 46.7 3.2e-17 62.5 18.7 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EEQ33556.1 - 0.0024 16.4 3.3 0.0024 16.4 3.3 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MttA_Hcf106 PF02416.16 EEQ33556.1 - 0.23 10.8 0.9 0.64 9.4 0.9 1.7 1 0 0 1 1 1 0 mttA/Hcf106 family V_ATPase_I PF01496.19 EEQ33557.1 - 0 1050.9 0.1 0 1050.6 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 EEQ33557.1 - 0.0072 16.3 3.6 0.43 10.5 0.2 2.4 2 0 0 2 2 2 2 Chemotaxis phosphatase, CheZ DUF1515 PF07439.11 EEQ33557.1 - 0.019 15.0 0.1 0.053 13.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Filament PF00038.21 EEQ33557.1 - 0.062 12.9 6.5 2.6 7.5 0.1 2.5 2 1 0 2 2 2 0 Intermediate filament protein DUF4988 PF16378.5 EEQ33557.1 - 0.12 12.0 0.2 0.29 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1664 PF07889.12 EEQ33557.1 - 0.13 12.3 3.2 10 6.2 0.1 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EEQ33557.1 - 0.2 12.2 1.5 5.4 7.6 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 EEQ33557.1 - 0.3 11.4 3.9 4.2 7.7 0.2 3.2 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tektin PF03148.14 EEQ33557.1 - 0.45 9.2 6.5 0.62 8.8 1.5 2.2 2 0 0 2 2 2 0 Tektin family DUF3552 PF12072.8 EEQ33557.1 - 0.54 9.6 4.0 7.5 5.9 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) FapA PF03961.13 EEQ33557.1 - 1.3 7.5 4.1 0.63 8.6 0.4 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A MOSC PF03473.17 EEQ33558.1 - 0.0017 18.4 0.1 0.0034 17.4 0.1 1.6 1 1 0 1 1 1 1 MOSC domain BLM10_mid PF16507.5 EEQ33559.1 - 8.8e-211 701.1 0.0 1.2e-210 700.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EEQ33559.1 - 1.2e-27 95.7 0.0 5.3e-27 93.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EEQ33559.1 - 5.4e-20 71.5 0.1 2.3e-19 69.5 0.0 2.2 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 EEQ33559.1 - 0.005 17.0 0.1 1.2 9.6 0.0 4.5 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.8 EEQ33559.1 - 0.0061 16.2 0.3 4.1 6.9 0.0 3.5 3 0 0 3 3 3 2 CLASP N terminal UL42 PF17638.2 EEQ33559.1 - 0.046 13.7 0.1 0.16 11.9 0.1 1.9 1 0 0 1 1 1 0 HCMV UL42 Mannosyl_trans2 PF04188.13 EEQ33560.1 - 4.4e-28 98.8 12.6 2.5e-22 79.8 4.7 2.1 2 0 0 2 2 2 2 Mannosyltransferase (PIG-V) Pro_CA PF00484.19 EEQ33563.1 - 1.1e-43 149.2 0.1 1.4e-43 148.9 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Velvet PF11754.8 EEQ33565.1 - 2.9e-48 165.0 10.6 2e-32 113.1 0.1 3.0 1 1 2 3 3 3 2 Velvet factor DUF736 PF05284.12 EEQ33566.1 - 0.0079 16.1 0.0 0.0098 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF736) MOZ_SAS PF01853.18 EEQ33568.1 - 6.9e-75 250.6 0.0 1.1e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EEQ33568.1 - 2.7e-21 74.9 2.6 6.7e-21 73.6 2.6 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain MWFE PF15879.5 EEQ33569.1 - 1.3e-23 82.8 0.0 1.7e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Acetyltransf_2 PF00797.17 EEQ33570.1 - 9e-42 143.5 0.0 1.2e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase RraA-like PF03737.15 EEQ33571.1 - 4e-31 108.2 0.0 5.2e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Aldolase/RraA Thiolase_N PF00108.23 EEQ33572.1 - 4.1e-74 249.2 2.9 4.1e-74 249.2 2.9 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EEQ33572.1 - 2.1e-43 146.8 0.1 4.5e-43 145.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EEQ33572.1 - 0.006 16.2 0.4 0.033 13.8 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SR-25 PF10500.9 EEQ33573.1 - 0.063 12.9 2.9 0.077 12.6 2.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GFO_IDH_MocA PF01408.22 EEQ33574.1 - 1.1e-18 68.2 0.0 2.7e-18 66.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold APH PF01636.23 EEQ33575.1 - 1.2e-08 35.2 1.0 2.7e-07 30.8 1.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ33575.1 - 2.8e-05 23.8 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EEQ33575.1 - 0.067 12.5 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Drf_GBD PF06371.13 EEQ33576.1 - 6.6e-18 64.9 4.9 5.4e-16 58.7 4.9 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Snf7 PF03357.21 EEQ33577.1 - 3e-44 150.7 11.0 3.6e-44 150.4 11.0 1.1 1 0 0 1 1 1 1 Snf7 CLZ PF16526.5 EEQ33577.1 - 0.00059 20.2 1.7 0.2 12.0 0.0 3.3 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Atg14 PF10186.9 EEQ33577.1 - 0.0079 15.3 2.1 0.0095 15.1 2.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4201 PF13870.6 EEQ33577.1 - 0.015 15.0 4.2 0.015 15.0 4.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 EEQ33577.1 - 0.02 15.3 6.6 0.49 10.9 2.3 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 EEQ33577.1 - 0.022 12.3 8.9 0.041 11.4 8.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4844 PF16133.5 EEQ33577.1 - 0.09 13.3 1.7 0.24 11.9 1.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4844) HHH_2 PF12826.7 EEQ33577.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Prefoldin PF02996.17 EEQ33577.1 - 0.14 12.0 3.7 6.9 6.6 0.0 3.3 2 1 2 4 4 4 0 Prefoldin subunit FlaC_arch PF05377.11 EEQ33577.1 - 0.33 11.4 5.1 50 4.4 3.4 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 EEQ33577.1 - 0.63 10.3 0.1 0.63 10.3 0.1 3.1 1 1 0 2 2 2 0 ABC transporter C-terminal domain DUF4094 PF13334.6 EEQ33577.1 - 1.5 9.3 4.4 6.8 7.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) SAPS PF04499.15 EEQ33578.1 - 6.5e-177 589.2 0.7 6.5e-177 589.2 0.7 2.1 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein SET PF00856.28 EEQ33579.1 - 0.0063 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 SET domain Complex1_51K PF01512.17 EEQ33580.1 - 2.5e-48 163.8 0.0 4.4e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EEQ33580.1 - 3.1e-29 100.9 2.0 3.9e-29 100.5 0.3 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EEQ33580.1 - 4.6e-09 36.0 0.0 2.7e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 SLBB domain Nup96 PF12110.8 EEQ33581.1 - 1.2e-76 257.6 0.0 1.8e-76 257.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EEQ33581.1 - 2e-51 174.0 0.0 3.4e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EEQ33581.1 - 7.6e-11 42.7 81.6 9.1e-09 36.1 42.0 12.0 5 2 5 10 10 10 2 Nucleoporin FG repeat region AMP-binding PF00501.28 EEQ33582.1 - 3.2e-90 302.7 0.0 4.1e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ33582.1 - 1.1e-27 96.9 2.0 7.2e-26 91.0 1.7 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EEQ33582.1 - 2.6e-16 59.2 0.1 6.8e-16 57.9 0.1 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus GET2 PF08690.10 EEQ33583.1 - 1e-11 45.1 0.1 2.6e-11 43.8 0.0 1.6 1 1 1 2 2 2 1 GET complex subunit GET2 C2 PF00168.30 EEQ33584.1 - 3.5e-29 101.1 0.0 3.1e-17 62.8 0.0 2.6 2 0 0 2 2 2 2 C2 domain IMS PF00817.20 EEQ33586.1 - 1.5e-39 135.4 0.0 2.3e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EEQ33586.1 - 1.2e-16 61.4 0.1 9.1e-16 58.6 0.1 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EEQ33586.1 - 0.085 12.5 0.9 0.16 11.6 0.9 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Reprolysin_5 PF13688.6 EEQ33587.1 - 1e-57 195.5 6.4 1e-57 195.5 6.4 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EEQ33587.1 - 1.4e-46 158.9 2.1 3.5e-46 157.6 2.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EEQ33587.1 - 2.4e-42 144.9 1.9 4.4e-42 144.0 1.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EEQ33587.1 - 3.9e-15 56.4 34.1 3.9e-15 56.4 34.1 4.2 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 EEQ33587.1 - 6.3e-12 46.1 0.1 3.5e-11 43.7 0.1 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 EEQ33587.1 - 8.6e-07 29.4 4.3 8.6e-07 29.4 4.3 4.9 1 1 2 3 3 3 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 EEQ33587.1 - 0.017 15.4 0.1 0.035 14.3 0.1 1.5 1 0 0 1 1 1 0 Reprolysin family propeptide Mid2 PF04478.12 EEQ33587.1 - 0.089 12.6 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 EEQ33587.1 - 0.089 12.2 0.3 0.18 11.2 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EF-hand_7 PF13499.6 EEQ33588.1 - 4e-16 59.2 0.9 5.5e-10 39.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EEQ33588.1 - 1.4e-14 52.5 1.5 1.9e-05 23.9 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EEQ33588.1 - 1.9e-13 49.1 3.4 1.9e-05 24.2 0.2 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EEQ33588.1 - 1.8e-11 43.7 1.1 1.3e-08 34.5 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EEQ33588.1 - 0.0084 16.1 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF3572 PF12096.8 EEQ33588.1 - 0.023 14.9 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) EF-hand_5 PF13202.6 EEQ33588.1 - 0.036 13.6 4.2 1.5 8.5 0.1 2.7 3 0 0 3 3 3 0 EF hand EFhand_Ca_insen PF08726.10 EEQ33588.1 - 0.16 12.1 0.3 0.56 10.3 0.0 2.0 2 1 1 3 3 3 0 Ca2+ insensitive EF hand MgsA_C PF12002.8 EEQ33589.1 - 7.5e-59 198.4 0.1 1.3e-58 197.6 0.1 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EEQ33589.1 - 2.4e-24 85.5 0.4 5.5e-24 84.3 0.4 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EEQ33589.1 - 4.9e-11 43.2 0.1 1.2e-10 41.9 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEQ33589.1 - 2.4e-07 30.6 0.0 1.7e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EEQ33589.1 - 0.00081 19.3 0.1 0.0028 17.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EEQ33589.1 - 0.018 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EEQ33589.1 - 0.026 14.3 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 EEQ33589.1 - 0.032 13.6 0.0 0.081 12.3 0.0 1.6 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI zf_UBZ PF18439.1 EEQ33589.1 - 0.18 11.4 0.7 0.5 10.0 0.3 2.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2H2_13 PF18508.1 EEQ33589.1 - 0.45 10.2 1.7 0.87 9.2 1.7 1.5 1 0 0 1 1 1 0 Zinc finger domain Aminotran_1_2 PF00155.21 EEQ33591.1 - 2e-65 221.3 0.0 2.3e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EEQ33591.1 - 0.025 13.9 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase KH_1 PF00013.29 EEQ33592.1 - 3.2e-46 155.0 7.1 1e-15 57.3 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EEQ33592.1 - 2e-11 43.5 2.0 0.0036 17.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EEQ33592.1 - 4.3e-09 36.1 4.4 0.042 13.7 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EEQ33592.1 - 0.008 16.2 3.6 11 6.2 0.1 3.4 3 0 0 3 3 3 1 NusA-like KH domain TFIIA PF03153.13 EEQ33592.1 - 1.1 9.2 27.9 0.26 11.2 23.6 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 EEQ33592.1 - 3.4 5.7 5.6 4.9 5.1 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.19 EEQ33592.1 - 5.8 6.7 19.4 2.8 7.8 7.2 2.3 2 0 0 2 2 2 0 SPX domain Suf PF05843.14 EEQ33592.1 - 6.6 6.6 13.2 1.1 9.2 5.5 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Amidoligase_2 PF12224.8 EEQ33593.1 - 1.7e-18 67.2 0.0 2.3e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme HHH_3 PF12836.7 EEQ33594.1 - 0.049 13.9 0.0 6.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif PDT PF00800.18 EEQ33595.1 - 0.041 13.7 0.1 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Prephenate dehydratase Ald_Xan_dh_C2 PF02738.18 EEQ33596.1 - 8e-204 678.1 0.3 1.1e-203 677.6 0.3 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EEQ33596.1 - 1.1e-45 155.4 0.0 2.2e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EEQ33596.1 - 2.8e-33 114.1 0.0 9.3e-33 112.5 0.0 2.0 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EEQ33596.1 - 3.2e-28 98.3 0.0 8.6e-28 96.9 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EEQ33596.1 - 7.2e-28 96.4 0.0 1.7e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EEQ33596.1 - 3.4e-08 33.3 0.4 9.3e-08 31.9 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.16 EEQ33596.1 - 0.084 13.0 0.0 0.59 10.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-70 region 3 NAD_binding_4 PF07993.12 EEQ33597.1 - 1.3e-71 240.8 0.0 1.8e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EEQ33597.1 - 1.1e-70 238.4 0.0 1.5e-70 238.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EEQ33597.1 - 1.1e-10 41.4 0.0 3e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 EEQ33597.1 - 4.8e-10 38.7 0.1 2.7e-09 36.2 0.1 1.9 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EEQ33597.1 - 2.1e-08 34.4 0.0 4.8e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ33597.1 - 0.0017 19.3 0.0 0.0064 17.4 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 EEQ33597.1 - 0.0041 16.2 0.0 0.013 14.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EEQ33597.1 - 0.023 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EEQ33597.1 - 0.057 13.3 0.0 8.9 6.2 0.0 2.5 2 0 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 EEQ33597.1 - 0.11 11.5 0.0 0.45 9.6 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain PRK PF00485.18 EEQ33598.1 - 7.1e-06 25.9 0.0 9.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EEQ33598.1 - 0.0023 18.5 0.1 0.022 15.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EEQ33598.1 - 0.0051 17.3 0.1 0.012 16.1 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EEQ33598.1 - 0.0054 17.1 0.2 0.011 16.1 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EEQ33598.1 - 0.036 13.2 0.0 0.12 11.5 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain MobB PF03205.14 EEQ33598.1 - 0.044 13.7 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 EEQ33598.1 - 0.06 13.0 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EEQ33598.1 - 0.069 13.3 1.3 0.76 9.9 0.0 2.1 1 1 0 2 2 2 0 AAA domain PTN13_u3 PF16599.5 EEQ33598.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ AAA_23 PF13476.6 EEQ33598.1 - 0.076 13.5 0.3 0.16 12.4 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EEQ33598.1 - 0.092 13.0 0.3 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EEQ33598.1 - 0.095 12.5 0.2 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase KTI12 PF08433.10 EEQ33598.1 - 0.099 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 T2SSE PF00437.20 EEQ33598.1 - 0.12 11.4 0.3 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein SNF2_N PF00176.23 EEQ33599.1 - 3e-38 131.4 0.0 1.9e-33 115.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ33599.1 - 8.8e-08 32.5 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HMG_box PF00505.19 EEQ33600.1 - 4.7e-21 75.0 0.0 8.3e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EEQ33600.1 - 5.5e-05 23.7 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Ribosomal_S6e PF01092.19 EEQ33601.1 - 4.3e-56 188.3 0.0 9.3e-56 187.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Pribosyltran_N PF13793.6 EEQ33602.1 - 1.7e-46 156.9 0.3 6.2e-45 151.9 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EEQ33602.1 - 7.7e-45 153.2 1.3 2.2e-37 128.9 0.5 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EEQ33602.1 - 9e-19 67.5 0.6 1e-17 64.1 0.3 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EEQ33602.1 - 0.014 14.9 0.1 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF913 PF06025.12 EEQ33603.1 - 7.3e-127 423.3 0.0 7.3e-127 423.3 0.0 6.4 5 2 0 5 5 5 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EEQ33603.1 - 2.4e-109 366.1 4.0 2.4e-109 366.1 4.0 4.3 6 0 0 6 6 6 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EEQ33603.1 - 2.5e-83 280.1 0.0 4.6e-83 279.2 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EEQ33603.1 - 1.6e-29 100.4 22.8 4.6e-10 38.6 3.2 3.9 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 EEQ33603.1 - 0.0082 16.0 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain NARP1 PF12569.8 EEQ33603.1 - 1.4 7.7 14.9 3.9 6.3 14.9 1.7 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 An_peroxidase PF03098.15 EEQ33604.1 - 7.4e-32 110.6 0.0 5.6e-19 68.1 0.0 3.2 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 EEQ33604.1 - 1.6e-07 30.5 0.0 1.1e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Steroid_dh PF02544.16 EEQ33605.1 - 2e-31 109.0 0.2 2.6e-31 108.7 0.2 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EEQ33605.1 - 6.8e-07 29.0 0.5 9.3e-07 28.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EEQ33605.1 - 2.3e-05 24.8 0.3 4.7e-05 23.7 0.3 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Hema_stalk PF08720.10 EEQ33605.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk Glyco_transf_34 PF05637.12 EEQ33606.1 - 2.4e-58 197.7 0.0 3.2e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_L28 PF00830.19 EEQ33607.1 - 9.1e-17 61.0 0.9 1.8e-16 60.0 0.9 1.5 1 0 0 1 1 1 1 Ribosomal L28 family FoP_duplication PF13865.6 EEQ33607.1 - 0.1 13.2 0.4 0.24 12.0 0.1 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 TIP49 PF06068.13 EEQ33608.1 - 6e-166 551.9 0.1 7.2e-166 551.7 0.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EEQ33608.1 - 5.3e-21 74.5 0.1 2.5e-20 72.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EEQ33608.1 - 1.9e-11 44.5 0.2 2.7e-07 31.1 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEQ33608.1 - 1.9e-10 40.7 0.1 5.2e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ33608.1 - 9.8e-06 25.9 0.1 0.047 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEQ33608.1 - 0.00012 22.5 0.2 0.0025 18.2 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EEQ33608.1 - 0.00041 20.6 0.1 0.001 19.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EEQ33608.1 - 0.0009 19.3 0.2 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EEQ33608.1 - 0.0015 18.9 4.0 0.054 13.8 4.0 2.3 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EEQ33608.1 - 0.0017 18.1 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 EEQ33608.1 - 0.004 17.6 0.1 0.062 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EEQ33608.1 - 0.0044 16.3 0.1 0.012 14.8 0.1 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 EEQ33608.1 - 0.0045 16.6 0.1 0.0093 15.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 EEQ33608.1 - 0.008 15.5 0.1 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain ATPase PF06745.13 EEQ33608.1 - 0.0092 15.3 0.5 0.078 12.3 0.0 2.4 3 0 0 3 3 3 1 KaiC Mg_chelatase PF01078.21 EEQ33608.1 - 0.017 14.5 0.1 0.82 9.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EEQ33608.1 - 0.032 14.3 0.0 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain TetR_C_30 PF17939.1 EEQ33608.1 - 0.048 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IstB_IS21 PF01695.17 EEQ33608.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 EEQ33608.1 - 0.057 14.0 0.1 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEQ33608.1 - 0.058 12.9 0.1 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 EEQ33608.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EEQ33608.1 - 0.099 12.4 0.2 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 EEQ33609.1 - 4.5e-16 58.7 0.2 6e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-SNARE PF05008.15 EEQ33611.1 - 8.2e-23 80.6 7.0 8.2e-23 80.6 7.0 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EEQ33611.1 - 1.4e-15 57.3 2.2 1.4e-15 57.3 2.2 2.8 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.18 EEQ33611.1 - 0.0055 15.0 1.6 0.18 10.0 0.1 2.3 2 0 0 2 2 2 2 Fusion glycoprotein F0 Sec20 PF03908.13 EEQ33611.1 - 0.015 15.2 2.7 0.042 13.8 0.1 2.4 2 2 0 2 2 2 0 Sec20 DUF1542 PF07564.11 EEQ33611.1 - 0.16 12.1 5.6 0.21 11.7 3.3 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) FUSC PF04632.12 EEQ33611.1 - 0.33 9.4 9.0 1.2 7.6 9.1 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family zf-C4H2 PF10146.9 EEQ33611.1 - 0.62 10.3 9.7 0.95 9.7 7.0 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein DUF349 PF03993.12 EEQ33611.1 - 0.79 10.1 10.0 2.9 8.2 0.5 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) TBCA PF02970.16 EEQ33611.1 - 1.1 9.6 7.9 0.64 10.4 2.5 2.6 2 1 1 3 3 3 0 Tubulin binding cofactor A DUF4355 PF14265.6 EEQ33611.1 - 1.4 9.2 10.4 0.12 12.6 5.2 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) Exonuc_VII_L PF02601.15 EEQ33611.1 - 1.7 8.2 13.2 3 7.3 13.3 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF2407_C PF13373.6 EEQ33612.1 - 1.5e-41 141.8 0.0 2.3e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EEQ33612.1 - 1.1e-35 122.3 0.0 2.3e-35 121.3 0.0 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EEQ33612.1 - 0.0075 16.0 0.0 0.017 14.8 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EEQ33612.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Zn_clus PF00172.18 EEQ33613.1 - 6.4e-08 32.6 7.5 1.3e-07 31.6 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EEQ33613.1 - 1.5e-06 27.3 0.0 2.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 EEQ33614.1 - 0.036 13.4 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Fe-S_biosyn PF01521.20 EEQ33615.1 - 2e-20 73.0 0.0 5e-20 71.8 0.0 1.6 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis Pro-kuma_activ PF09286.11 EEQ33615.1 - 0.12 12.6 0.0 0.67 10.3 0.0 2.0 2 1 1 3 3 3 0 Pro-kumamolisin, activation domain 2OG-Fe_Oxy_2 PF10014.9 EEQ33616.1 - 1e-51 175.5 0.2 1.2e-51 175.2 0.2 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase MFS_1 PF07690.16 EEQ33617.1 - 9.6e-09 34.6 7.5 1.4e-08 34.0 6.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1741 PF08427.10 EEQ33618.1 - 1.6e-85 286.5 0.3 3e-85 285.6 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Erf4 PF10256.9 EEQ33618.1 - 0.15 12.2 0.2 0.75 9.9 0.0 2.3 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family MRG PF05712.13 EEQ33619.1 - 2.6e-45 154.2 2.1 3e-35 121.3 0.3 2.2 1 1 1 2 2 2 2 MRG Tudor-knot PF11717.8 EEQ33619.1 - 7.1e-08 32.2 2.2 1.7e-07 31.0 2.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.10 EEQ33620.1 - 1.8e-28 98.5 2.2 3e-28 97.7 2.2 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein YabA PF06156.13 EEQ33620.1 - 0.033 14.8 1.5 2.6 8.7 0.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 EEQ33620.1 - 0.045 14.3 5.0 0.19 12.3 0.1 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Med4 PF10018.9 EEQ33620.1 - 0.068 12.9 1.6 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Sld5 PF05916.11 EEQ33620.1 - 0.12 12.8 2.0 1.3 9.5 0.3 2.2 1 1 1 2 2 2 0 GINS complex protein Ctf8 PF09696.10 EEQ33622.1 - 1.7e-48 164.6 0.1 2e-48 164.4 0.1 1.1 1 0 0 1 1 1 1 Ctf8 Glyoxalase PF00903.25 EEQ33623.1 - 2.4e-18 66.5 0.1 1.1e-16 61.2 0.0 2.5 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EEQ33623.1 - 2.2e-09 37.6 0.0 1.4e-05 25.3 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EEQ33623.1 - 5.1e-06 26.7 0.0 0.3 11.2 0.0 3.3 2 2 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EEQ33623.1 - 0.0037 17.4 0.0 0.029 14.6 0.0 2.2 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal HTH_11 PF08279.12 EEQ33623.1 - 0.1 12.6 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 HTH domain RabGAP-TBC PF00566.18 EEQ33624.1 - 7.6e-51 172.8 0.3 7.6e-51 172.8 0.3 2.9 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Mago_nashi PF02792.14 EEQ33624.1 - 0.45 10.6 2.9 0.32 11.1 0.5 1.9 1 1 0 1 1 1 0 Mago nashi protein PPTA PF01239.22 EEQ33625.1 - 4.9e-38 127.8 6.2 2.6e-08 33.3 1.2 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat HalX PF08663.10 EEQ33625.1 - 0.41 11.0 4.3 0.51 10.7 0.4 2.7 2 0 0 2 2 2 0 HalX domain WD40 PF00400.32 EEQ33626.1 - 8.3e-09 35.9 0.1 0.00023 21.9 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33626.1 - 1.7e-05 25.0 0.3 0.034 14.4 0.1 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain APH PF01636.23 EEQ33627.1 - 7.6e-16 58.7 0.0 1.7e-15 57.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Utp12 PF04003.12 EEQ33628.1 - 1.9e-23 82.8 0.1 9.6e-23 80.5 0.2 2.1 2 0 0 2 2 2 1 Dip2/Utp12 Family DUF212 PF02681.14 EEQ33628.1 - 0.075 13.2 0.4 0.17 12.0 0.4 1.5 1 0 0 1 1 1 0 Divergent PAP2 family BET PF17035.5 EEQ33629.1 - 4e-19 68.5 0.5 9.7e-19 67.3 0.5 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 EEQ33629.1 - 9.3e-19 67.3 1.2 1.2e-18 66.9 0.2 1.7 2 0 0 2 2 2 1 Bromodomain DUF3573 PF12097.8 EEQ33629.1 - 0.051 12.4 2.4 0.048 12.5 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) zf-CSL PF05207.13 EEQ33630.1 - 5e-21 74.2 0.1 6.4e-21 73.9 0.1 1.1 1 0 0 1 1 1 1 CSL zinc finger Frataxin_Cyay PF01491.16 EEQ33631.1 - 2.4e-34 117.6 0.0 3.3e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Rsbr_N PF08678.10 EEQ33631.1 - 0.077 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Rsbr N terminal LIME1 PF15332.6 EEQ33631.1 - 0.1 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 AKAP7_NLS PF10469.9 EEQ33632.1 - 8.2e-14 52.0 0.0 3e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.13 EEQ33633.1 - 2.8e-174 580.7 2.9 3.9e-174 580.2 2.9 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 NUC130_3NT PF08158.12 EEQ33633.1 - 0.083 13.2 0.0 7.7 6.9 0.0 3.3 3 0 0 3 3 3 0 NUC130/3NT domain LprI PF07007.12 EEQ33633.1 - 5.3 7.7 5.9 1.7 9.4 1.4 2.7 2 1 0 2 2 2 0 Lysozyme inhibitor LprI Ribosomal_L30 PF00327.20 EEQ33634.1 - 1.8e-12 47.0 0.2 2.4e-12 46.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e OstA_2 PF13100.6 EEQ33634.1 - 0.18 11.4 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 OstA-like protein Pyridoxal_deC PF00282.19 EEQ33635.1 - 2.4e-14 52.8 0.0 4.4e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EEQ33635.1 - 1.1e-06 27.8 0.0 6.2e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ33635.1 - 0.0008 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EEQ33635.1 - 0.074 11.6 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEQ33636.1 - 2.4e-91 306.7 0.0 2.7e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.26 EEQ33638.1 - 3e-19 68.3 28.5 3.8e-05 23.9 1.8 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ33638.1 - 1e-16 60.5 25.9 1.4e-06 28.5 1.5 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ33638.1 - 1e-09 38.4 27.2 0.0041 17.8 1.2 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ33638.1 - 7.1e-05 23.0 6.8 0.45 10.9 0.1 4.9 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EEQ33638.1 - 0.0047 17.5 12.1 0.17 12.5 0.6 4.5 4 1 1 5 5 5 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EEQ33638.1 - 0.02 15.0 2.1 2.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 EEQ33638.1 - 0.026 14.3 0.7 0.026 14.3 0.7 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 EEQ33638.1 - 0.052 13.1 2.2 0.95 9.1 0.2 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 EEQ33638.1 - 0.13 12.6 17.5 0.3 11.5 0.2 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type RIC3 PF15361.6 EEQ33638.1 - 0.94 9.9 4.8 1.2 9.5 1.7 2.6 1 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 HNH PF01844.23 EEQ33638.1 - 5.4 7.3 9.5 17 5.7 0.1 4.0 4 0 0 4 4 4 0 HNH endonuclease BTB PF00651.31 EEQ33639.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain zf-C2H2_4 PF13894.6 EEQ33639.1 - 0.24 12.3 5.2 6 8.0 0.7 3.3 2 1 1 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EEQ33639.1 - 0.33 11.0 1.6 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DZR PF12773.7 EEQ33639.1 - 0.69 10.0 6.2 1.1 9.3 6.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.26 EEQ33639.1 - 4.9 7.8 10.9 3.5 8.3 0.1 3.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type Methyltransf_23 PF13489.6 EEQ33640.1 - 3.7e-20 72.4 0.0 1.6e-19 70.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ33640.1 - 1e-14 54.9 0.0 4.7e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ33640.1 - 1.4e-12 48.2 0.0 3.6e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ33640.1 - 7.3e-12 45.8 0.0 2.7e-10 40.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ33640.1 - 1.1e-09 38.2 0.0 3.6e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EEQ33640.1 - 0.015 14.9 0.0 0.61 9.7 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.17 EEQ33640.1 - 0.13 11.4 0.1 1 8.5 0.0 2.2 3 0 0 3 3 3 0 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.6 EEQ33640.1 - 0.2 12.7 0.0 0.39 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Prp18 PF02840.15 EEQ33640.1 - 0.25 11.4 0.1 0.42 10.6 0.1 1.3 1 0 0 1 1 1 0 Prp18 domain Pkinase PF00069.25 EEQ33642.1 - 1.1e-07 31.6 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EEQ33642.1 - 1e-06 28.3 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ33642.1 - 0.00014 21.9 0.1 0.00067 19.7 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EEQ33642.1 - 0.013 14.9 0.2 0.023 14.0 0.2 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 EEQ33642.1 - 0.034 13.7 0.1 0.034 13.7 0.1 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EEQ33642.1 - 0.051 12.4 0.2 0.072 11.8 0.2 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EEQ33642.1 - 0.066 12.8 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 EEQ33642.1 - 0.095 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase E1-E2_ATPase PF00122.20 EEQ33643.1 - 6e-30 104.1 0.3 6e-30 104.1 0.3 3.3 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EEQ33643.1 - 3.9e-28 98.4 3.9 3.9e-28 98.4 3.9 2.2 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EEQ33643.1 - 5.1e-24 84.2 0.0 1.1e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EEQ33643.1 - 5.8e-15 54.7 0.2 1.4e-14 53.5 0.2 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EEQ33643.1 - 9.2e-07 29.4 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEQ33643.1 - 0.0015 18.3 0.8 0.0026 17.5 0.8 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase BRAP2 PF07576.12 EEQ33644.1 - 8.1e-33 112.6 0.0 1.5e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EEQ33644.1 - 7.6e-20 71.0 3.7 3.1e-19 69.0 3.7 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EEQ33644.1 - 1.6e-08 34.7 9.2 1.6e-08 34.7 9.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ33644.1 - 2.4e-06 27.3 8.7 2.4e-06 27.3 8.7 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEQ33644.1 - 0.00056 19.6 5.2 0.00056 19.6 5.2 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EEQ33644.1 - 0.00063 19.6 7.7 0.00063 19.6 7.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ33644.1 - 0.00081 19.3 7.2 0.00081 19.3 7.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EEQ33644.1 - 0.00081 19.2 5.4 0.00081 19.2 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ33644.1 - 0.00086 19.5 6.4 0.00086 19.5 6.4 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEQ33644.1 - 0.0014 18.6 5.5 0.0014 18.6 5.5 2.4 2 1 1 3 3 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EEQ33644.1 - 0.016 15.1 4.9 0.016 15.1 4.9 3.6 3 1 1 4 4 2 0 Prokaryotic RING finger family 4 ATG16 PF08614.11 EEQ33644.1 - 0.016 15.4 12.0 0.032 14.5 12.0 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1993 PF09351.10 EEQ33644.1 - 0.055 13.6 4.3 0.89 9.7 4.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) zf-ANAPC11 PF12861.7 EEQ33644.1 - 0.062 13.3 8.1 0.055 13.5 6.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ZapB PF06005.12 EEQ33644.1 - 0.079 13.4 4.8 0.17 12.4 0.3 2.7 1 1 1 2 2 2 0 Cell division protein ZapB HALZ PF02183.18 EEQ33644.1 - 0.099 12.9 2.1 3.2 8.1 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper TLE_N PF03920.15 EEQ33644.1 - 0.13 12.4 3.2 0.31 11.1 0.9 2.4 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Lectin_N PF03954.14 EEQ33644.1 - 0.25 11.1 3.1 0.13 12.0 0.7 1.7 2 0 0 2 2 1 0 Hepatic lectin, N-terminal domain zf-UBP_var PF17807.1 EEQ33644.1 - 0.25 11.1 5.7 0.081 12.7 1.9 2.1 1 1 1 2 2 2 0 Variant UBP zinc finger CLZ PF16526.5 EEQ33644.1 - 0.29 11.5 5.4 0.19 12.1 1.4 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-RING_6 PF14835.6 EEQ33644.1 - 0.29 11.0 10.4 0.068 13.1 6.1 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein ERM PF00769.19 EEQ33644.1 - 0.32 10.8 15.4 0.53 10.1 15.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 EEQ33644.1 - 0.82 8.9 13.4 2.1 7.6 12.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) JAKMIP_CC3 PF16034.5 EEQ33644.1 - 0.86 9.5 10.5 0.086 12.8 5.8 1.7 2 0 0 2 2 1 0 JAKMIP CC3 domain PGBA_C PF15437.6 EEQ33644.1 - 0.97 9.8 5.7 0.16 12.3 1.4 1.9 2 0 0 2 2 1 0 Plasminogen-binding protein pgbA C-terminal TPR_MLP1_2 PF07926.12 EEQ33644.1 - 1.6 8.8 17.5 3.6 7.7 17.5 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 EEQ33644.1 - 2.4 8.1 4.3 0.82 9.6 0.6 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Exonuc_VII_L PF02601.15 EEQ33644.1 - 2.5 7.6 6.3 4.8 6.7 6.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit SHE3 PF17078.5 EEQ33644.1 - 4.9 6.8 10.6 6.9 6.3 8.2 2.3 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 DivIC PF04977.15 EEQ33644.1 - 5.2 6.9 7.8 3.6 7.4 0.4 2.5 1 1 0 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 EEQ33644.1 - 5.3 7.1 7.9 11 6.1 7.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ubiquitin PF00240.23 EEQ33645.1 - 1.6e-134 437.8 21.6 4e-33 113.0 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EEQ33645.1 - 6.9e-63 208.4 22.6 3e-15 55.8 0.8 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEQ33645.1 - 1.5e-22 79.8 11.6 0.00043 20.7 0.2 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EEQ33645.1 - 6.5e-16 58.0 4.4 0.03 14.3 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EEQ33645.1 - 3.3e-14 53.0 8.3 0.048 14.0 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEQ33645.1 - 3.6e-14 52.8 3.1 0.13 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EEQ33645.1 - 3.2e-13 50.1 2.0 0.29 11.7 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EEQ33645.1 - 1.2e-09 38.2 1.0 1.2 8.9 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EEQ33645.1 - 7.7e-07 29.1 25.0 17 5.5 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 EEQ33645.1 - 1.4e-06 27.8 0.7 1.4 8.2 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 EEQ33645.1 - 2.5e-06 27.6 2.8 11 6.3 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 EEQ33645.1 - 6.2e-06 26.5 0.0 30 5.1 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) Big_7 PF17957.1 EEQ33645.1 - 8.8e-06 26.4 0.2 35 5.3 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain Big_3_3 PF13750.6 EEQ33645.1 - 0.00011 21.9 0.1 32 4.1 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) NEAT PF05031.12 EEQ33645.1 - 0.00012 22.6 2.4 0.52 10.9 1.6 2.8 1 1 1 2 2 2 2 Iron Transport-associated domain UDP-g_GGTase PF06427.11 EEQ33645.1 - 0.00021 21.3 5.1 6.6 6.9 0.1 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 EEQ33645.1 - 0.00022 21.0 5.1 19 5.2 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF969 PF06149.12 EEQ33645.1 - 0.00022 20.7 0.0 19 4.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) DUF493 PF04359.14 EEQ33645.1 - 0.0021 18.6 0.1 1.3e+02 3.3 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ACT_4 PF13291.6 EEQ33645.1 - 0.0026 18.3 1.1 1.2e+02 3.4 0.0 4.2 4 0 0 4 4 4 0 ACT domain Raf1_HTH PF18579.1 EEQ33645.1 - 0.0041 16.8 0.2 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ORF11CD3 PF10549.9 EEQ33645.1 - 0.0047 17.0 0.0 91 3.3 0.0 4.6 4 0 0 4 4 4 0 ORF11CD3 domain YcgR_2 PF12945.7 EEQ33645.1 - 0.0069 16.5 6.5 46 4.3 0.1 4.2 4 0 0 4 4 4 0 Flagellar protein YcgR Phage-tail_1 PF09097.10 EEQ33645.1 - 0.087 12.6 1.1 1.3e+02 2.2 0.0 3.8 4 0 0 4 4 4 0 Baseplate structural protein, domain 1 Tash_PEST PF07708.11 EEQ33645.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif ProRS-C_2 PF09181.10 EEQ33645.1 - 0.14 12.3 5.8 1.1e+02 3.0 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Myosin_N PF02736.19 EEQ33645.1 - 0.2 11.5 6.3 1.1e+02 2.8 0.0 5.3 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain DMA PF03474.14 EEQ33645.1 - 0.29 10.8 4.0 1e+02 2.6 0.0 4.1 4 0 0 4 4 4 0 DMRTA motif Phage_sheath_1N PF17481.2 EEQ33645.1 - 0.88 10.1 9.4 4.9e+03 -2.0 9.4 4.0 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain FlgD_ig PF13860.6 EEQ33645.1 - 0.95 9.4 9.4 92 3.0 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Zn_clus PF00172.18 EEQ33646.1 - 0.0085 16.2 7.8 0.0085 16.2 7.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.21 EEQ33647.1 - 3.5e-29 100.2 36.8 1.6e-12 46.9 1.6 6.4 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat PY_rept_46 PF09689.10 EEQ33647.1 - 0.026 15.1 2.1 0.044 14.4 2.1 1.3 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) DUF3464 PF11947.8 EEQ33647.1 - 0.063 13.0 0.7 0.11 12.3 0.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CoA_binding_3 PF13727.6 EEQ33647.1 - 0.23 11.5 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 CoA-binding domain dsrm PF00035.26 EEQ33648.1 - 0.00018 22.1 0.0 0.00034 21.2 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EEQ33648.1 - 0.011 16.0 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Period_C PF12114.8 EEQ33649.1 - 3.2 7.3 5.9 4.8 6.7 5.9 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF4448 PF14610.6 EEQ33650.1 - 1.4e-39 135.8 0.0 2.4e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) LapA_dom PF06305.11 EEQ33650.1 - 0.033 14.0 0.8 0.072 12.9 0.8 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Podoplanin PF05808.11 EEQ33650.1 - 2 8.5 9.1 3.3 7.8 9.1 1.3 1 0 0 1 1 1 0 Podoplanin Hpt PF01627.23 EEQ33651.1 - 1.3e-12 47.8 0.0 2.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Hpt domain HMGL-like PF00682.19 EEQ33652.1 - 1.6e-59 201.7 1.0 3.4e-48 164.5 0.3 2.4 1 1 1 2 2 2 2 HMGL-like FMN_dh PF01070.18 EEQ33652.1 - 0.088 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PTH2 PF01981.16 EEQ33654.1 - 1.1e-42 145.0 0.1 1.4e-42 144.7 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SART-1 PF03343.13 EEQ33655.1 - 1.2e-184 615.4 65.6 1.2e-184 615.4 65.6 1.4 2 0 0 2 2 2 1 SART-1 family WD40 PF00400.32 EEQ33656.1 - 3.9e-15 56.0 11.9 0.00016 22.4 0.5 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Occludin_ELL PF07303.13 EEQ33657.1 - 0.11 13.2 3.1 0.13 13.0 1.1 2.1 2 0 0 2 2 2 0 Occludin homology domain DUF155 PF02582.14 EEQ33661.1 - 2e-53 181.1 0.0 3.7e-53 180.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CDC45 PF02724.14 EEQ33661.1 - 9.1 4.4 25.1 1.1 7.4 4.8 2.1 2 0 0 2 2 2 0 CDC45-like protein Aldedh PF00171.22 EEQ33662.1 - 1e-147 492.4 0.2 1.3e-147 492.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_inhib PF16857.5 EEQ33662.1 - 0.36 10.7 1.5 9.6 6.1 0.9 2.4 2 0 0 2 2 2 0 RNA polymerase inhibitor Sel1 PF08238.12 EEQ33663.1 - 6.9e-32 109.2 49.4 9.6e-05 22.9 0.6 12.6 13 1 1 14 14 14 8 Sel1 repeat Mei5 PF10376.9 EEQ33663.1 - 0.0056 16.6 7.7 0.043 13.7 1.9 2.4 2 1 0 2 2 2 2 Double-strand recombination repair protein Drc1-Sld2 PF11719.8 EEQ33663.1 - 0.0083 15.7 11.5 0.014 15.0 11.5 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein Nucleo_P87 PF07267.11 EEQ33663.1 - 0.12 11.2 8.4 0.18 10.7 8.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Dus PF01207.17 EEQ33664.1 - 4.4e-42 144.3 0.0 8.3e-30 103.9 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 EEQ33664.1 - 0.00017 21.4 2.8 0.026 14.4 0.4 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ33664.1 - 0.0015 18.5 9.2 0.074 13.1 1.8 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EEQ33664.1 - 0.0051 16.6 1.0 0.0051 16.6 1.0 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger Kelch_4 PF13418.6 EEQ33665.1 - 3.2e-23 81.5 4.7 8.5e-07 28.9 0.0 4.6 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EEQ33665.1 - 3.1e-21 74.9 0.8 1.3e-05 25.0 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EEQ33665.1 - 7.3e-21 73.3 2.4 6.1e-07 29.2 0.1 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 EEQ33665.1 - 1.1e-19 69.8 0.1 7.7e-06 25.4 0.1 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EEQ33665.1 - 5.2e-18 64.6 4.1 3.4e-05 24.0 0.0 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EEQ33665.1 - 1.9e-16 59.9 3.3 3.5e-06 27.1 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain BTB PF00651.31 EEQ33665.1 - 1.4e-08 35.0 0.0 2.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 EEQ33666.1 - 6.1e-16 58.5 14.1 0.00047 20.9 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ33666.1 - 3.8e-15 55.9 4.0 1.6e-05 25.1 0.1 4.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ33666.1 - 1.8e-05 23.8 0.0 0.00092 18.3 0.0 3.0 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EEQ33666.1 - 0.00032 20.6 0.3 0.031 14.2 0.1 2.5 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A TFIIA PF03153.13 EEQ33667.1 - 5.3e-87 293.5 15.6 6.1e-87 293.3 15.6 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ntox1 PF15500.6 EEQ33667.1 - 0.053 13.9 0.2 0.14 12.5 0.2 1.7 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 DUF3391 PF11871.8 EEQ33667.1 - 0.38 11.3 3.3 0.63 10.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF2563 PF10817.8 EEQ33667.1 - 1.3 9.7 4.2 0.67 10.6 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2563) zf-C2H2_aberr PF17017.5 EEQ33668.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger DUF4719 PF15843.5 EEQ33668.1 - 0.1 12.7 0.0 0.1 12.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4719) DUF5421 PF17458.2 EEQ33668.1 - 2.8 7.2 13.2 0.42 9.9 8.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5421) Bap31 PF05529.12 EEQ33669.1 - 1.5e-48 164.1 7.2 1.9e-48 163.7 7.2 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EEQ33669.1 - 4e-14 52.3 4.1 6.6e-14 51.7 4.1 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 EEQ33669.1 - 0.024 14.4 1.5 0.11 12.3 0.4 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF4349 PF14257.6 EEQ33669.1 - 0.042 13.3 0.2 0.042 13.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) TMF_TATA_bd PF12325.8 EEQ33669.1 - 0.062 13.5 0.3 0.12 12.6 0.2 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 EEQ33669.1 - 0.21 10.7 1.0 0.25 10.4 1.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MMM1 PF10296.9 EEQ33670.1 - 8.9e-08 31.6 0.0 2.3e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 SesA PF17107.5 EEQ33674.1 - 2.5e-36 124.6 3.3 4.3e-36 123.8 0.7 2.3 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 EEQ33674.1 - 5.4e-08 32.9 2.3 5.4e-08 32.9 2.3 2.1 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EEQ33674.1 - 1.2e-06 29.0 3.5 4.7e-05 23.8 2.0 3.4 2 2 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 EEQ33674.1 - 0.00082 18.7 2.7 0.0034 16.7 0.4 2.3 1 1 0 2 2 2 1 KAP family P-loop domain AAA_18 PF13238.6 EEQ33674.1 - 0.0011 19.5 0.0 0.0032 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EEQ33674.1 - 0.0019 18.6 0.0 0.0068 16.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 EEQ33674.1 - 0.0032 17.4 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 EEQ33674.1 - 0.009 16.4 0.1 0.34 11.3 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 EEQ33674.1 - 0.0098 16.2 1.6 0.1 12.8 1.1 2.8 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.22 EEQ33674.1 - 0.024 13.8 0.1 0.12 11.6 0.0 2.1 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.6 EEQ33674.1 - 0.037 14.2 0.0 0.094 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EEQ33674.1 - 0.046 13.4 0.1 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Thymidylate kinase Cytidylate_kin PF02224.18 EEQ33674.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_30 PF13604.6 EEQ33674.1 - 0.081 12.6 0.1 0.19 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 EEQ33675.1 - 2.2e-63 214.1 0.0 3.4e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ33675.1 - 1.2e-34 119.8 0.0 3.2e-29 102.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEQ33675.1 - 2.7e-06 26.9 0.1 0.0006 19.2 0.1 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EEQ33675.1 - 0.0005 20.1 0.0 0.0015 18.5 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EEQ33675.1 - 0.0035 17.0 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EEQ33675.1 - 0.016 14.1 0.3 0.026 13.5 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EEQ33675.1 - 0.032 13.6 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Senescence PF06911.12 EEQ33676.1 - 1.4e-53 181.9 0.6 2.2e-53 181.3 0.6 1.3 1 0 0 1 1 1 1 Senescence-associated protein Stanniocalcin PF03298.13 EEQ33677.1 - 0.00046 19.6 0.0 0.00055 19.3 0.0 1.1 1 0 0 1 1 1 1 Stanniocalcin family Acyl-CoA_dh_1 PF00441.24 EEQ33678.1 - 1e-37 129.6 6.4 1.7e-37 128.9 6.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EEQ33678.1 - 1.3e-30 106.3 2.0 1.6e-30 106.0 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EEQ33678.1 - 2.2e-23 82.3 0.0 6.4e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EEQ33678.1 - 2.5e-14 53.7 2.4 5.3e-14 52.6 2.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AgrD PF05931.11 EEQ33678.1 - 0.006 16.6 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 Staphylococcal AgrD protein HpaB_N PF11794.8 EEQ33678.1 - 0.0088 15.7 0.0 0.026 14.2 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF3662 PF12401.8 EEQ33678.1 - 0.085 13.2 0.0 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2662) MFS_1 PF07690.16 EEQ33679.1 - 4.7e-27 94.8 36.9 5.6e-22 78.1 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EEQ33679.1 - 2.5e-05 23.3 1.9 2.5e-05 23.3 1.9 2.5 2 0 0 2 2 2 1 MFS_1 like family GWT1 PF06423.12 EEQ33681.1 - 1.3e-38 132.4 5.3 1.9e-38 131.9 3.1 2.3 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 EEQ33681.1 - 0.23 12.0 0.0 0.23 12.0 0.0 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4818) Amidase PF01425.21 EEQ33682.1 - 1.9e-79 267.8 0.1 8.6e-79 265.6 0.1 1.8 1 1 0 1 1 1 1 Amidase DnaJ PF00226.31 EEQ33683.1 - 4.7e-16 58.6 0.8 1.2e-15 57.3 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EEQ33683.1 - 4.2e-12 45.8 0.0 2.8e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain COS PF18568.1 EEQ33683.1 - 0.11 12.4 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain Peptidase_M24 PF00557.24 EEQ33684.1 - 9.7e-48 162.6 0.0 1.5e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EEQ33684.1 - 5.1e-24 84.4 0.0 8.9e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SPRY PF00622.28 EEQ33686.1 - 2.2e-19 69.7 0.0 4.1e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 SPRY domain DUF3611 PF12263.8 EEQ33686.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) TFIIA PF03153.13 EEQ33686.1 - 1.5 8.7 8.3 0.24 11.4 4.5 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PDEase_II PF02112.15 EEQ33687.1 - 6e-35 120.9 0.0 1.7e-17 63.6 0.0 3.0 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EEQ33687.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EEQ33687.1 - 0.011 15.8 0.9 0.022 14.8 0.9 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Fungal_trans PF04082.18 EEQ33688.1 - 4.6e-10 39.0 0.0 7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EEQ33689.1 - 1.5e-17 63.7 0.0 9.5e-15 54.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ33689.1 - 9.1e-10 38.5 0.0 1.7e-06 27.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ33689.1 - 7.2e-08 32.5 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.18 EEQ33690.1 - 6.8e-09 35.7 11.7 1.7e-08 34.4 11.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ALO PF04030.14 EEQ33692.1 - 1.2e-92 310.4 0.1 1.8e-92 309.9 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EEQ33692.1 - 2.1e-31 108.5 0.1 3.3e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4045 PF13254.6 EEQ33694.1 - 1.8e-90 304.6 52.5 1.8e-51 176.1 30.9 6.5 3 3 3 6 6 6 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 EEQ33694.1 - 6e-13 48.5 0.0 0.0036 17.2 0.0 3.9 3 0 0 3 3 3 3 Gelsolin repeat Arf PF00025.21 EEQ33695.1 - 2.7e-51 173.5 1.6 1.2e-48 164.9 1.6 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EEQ33695.1 - 4.2e-08 32.7 0.8 0.007 15.6 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EEQ33695.1 - 0.00011 22.4 0.2 0.38 11.0 0.1 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EEQ33695.1 - 0.00084 18.8 0.1 0.25 10.7 0.0 2.1 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ33695.1 - 0.0011 19.0 0.1 0.016 15.3 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EEQ33695.1 - 0.0033 17.0 0.0 0.035 13.7 0.0 1.8 1 1 1 2 2 2 1 Ras family HCV_NS1 PF01560.17 EEQ33695.1 - 0.019 13.7 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 SRPRB PF09439.10 EEQ33695.1 - 0.066 12.6 0.0 2 7.8 0.1 2.1 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EEQ33695.1 - 0.16 11.5 0.2 2.4 7.6 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B Acetyltransf_1 PF00583.25 EEQ33696.1 - 0.031 14.5 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ33696.1 - 0.17 12.3 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.29 EEQ33697.1 - 1e-45 155.7 0.0 1.7e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ33697.1 - 2e-30 105.4 0.2 2.1e-28 98.9 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EEQ33697.1 - 0.0011 17.9 2.1 0.0023 16.8 0.1 2.4 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 HMGL-like PF00682.19 EEQ33698.1 - 7.6e-82 274.8 0.0 1.3e-81 274.0 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EEQ33698.1 - 5.4e-21 74.9 0.0 1e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain PPK2 PF03976.14 EEQ33698.1 - 0.03 13.8 0.2 0.07 12.6 0.2 1.5 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Self-incomp_S1 PF05938.11 EEQ33698.1 - 0.12 13.0 0.1 7 7.2 0.0 2.4 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 AMP-binding PF00501.28 EEQ33699.1 - 2.5e-65 220.7 0.1 2.9e-37 128.3 0.0 4.5 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 EEQ33699.1 - 1.3e-09 38.9 0.1 4.4e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 EEQ33699.1 - 0.011 15.8 0.4 0.022 14.8 0.4 1.5 1 0 0 1 1 1 0 Gas vesicle protein G Carb_anhydrase PF00194.21 EEQ33700.1 - 8.6e-34 117.2 0.0 1.9e-33 116.1 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RNR_inhib PF08591.10 EEQ33701.1 - 3.9e-27 95.7 1.1 1.2e-26 94.1 0.6 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor SDA1 PF05285.12 EEQ33702.1 - 2e-88 297.2 44.3 2e-88 297.2 44.3 2.6 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EEQ33702.1 - 1.4e-22 79.7 0.1 3.8e-22 78.4 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Ribosomal_S7 PF00177.21 EEQ33703.1 - 4.2e-37 127.1 1.7 5.2e-37 126.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Methyltransf_23 PF13489.6 EEQ33704.1 - 1e-16 61.2 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ33704.1 - 1.3e-11 45.0 0.0 3.5e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ33704.1 - 1.5e-07 32.1 0.0 1.9e-06 28.5 0.0 2.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ33704.1 - 2.9e-06 27.2 0.0 4.2e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ33704.1 - 2.9e-06 27.8 0.0 6.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEQ33704.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EEQ33704.1 - 0.0014 18.3 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 EEQ33704.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain PrmA PF06325.13 EEQ33704.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EEQ33704.1 - 0.05 13.7 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EEQ33704.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 EEQ33704.1 - 0.18 11.1 0.0 1.4 8.2 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.22 EEQ33705.1 - 3.6e-61 207.3 0.0 4.3e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 EEQ33706.1 - 1.6e-11 45.1 1.2 2.6e-11 44.4 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EEQ33706.1 - 0.0084 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain 4HBT_3 PF13622.6 EEQ33707.1 - 4.9e-76 256.3 0.8 6e-76 256.0 0.8 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EEQ33707.1 - 3e-24 85.4 0.0 1.2e-10 41.3 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase DUF3445 PF11927.8 EEQ33708.1 - 1.2e-61 208.3 0.0 2.1e-61 207.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3445) HSP70 PF00012.20 EEQ33710.1 - 3.3e-10 38.8 0.1 7.1e-09 34.4 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EEQ33710.1 - 0.13 11.0 0.0 0.37 9.6 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein N2227 PF07942.12 EEQ33711.1 - 1.7e-57 194.7 0.0 2.6e-39 135.1 0.0 2.7 1 1 1 2 2 2 2 N2227-like protein SelP_N PF04592.14 EEQ33711.1 - 0.25 10.7 6.3 0.42 10.0 6.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Fungal_trans PF04082.18 EEQ33714.1 - 2.6e-20 72.6 0.3 4.7e-20 71.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ33714.1 - 0.0015 18.6 3.4 0.0046 17.0 3.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DVL PF08137.12 EEQ33714.1 - 6.8 6.6 6.4 19 5.2 6.4 1.8 1 0 0 1 1 1 0 DVL family Prefoldin_2 PF01920.20 EEQ33715.1 - 4.8e-23 81.1 4.8 6.2e-23 80.8 4.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit GPS2_interact PF15784.5 EEQ33715.1 - 0.0029 18.0 0.7 0.0029 18.0 0.7 2.2 1 1 1 2 2 2 1 G-protein pathway suppressor 2-interacting domain Osmo_CC PF08946.10 EEQ33715.1 - 0.083 13.2 3.4 0.21 11.8 3.4 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF3338 PF11819.8 EEQ33715.1 - 0.11 12.5 7.5 2.1 8.4 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) Mei5 PF10376.9 EEQ33715.1 - 0.2 11.5 8.5 0.27 11.1 8.5 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF1664 PF07889.12 EEQ33715.1 - 0.47 10.5 3.3 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EEQ33715.1 - 1.3 7.8 12.0 0.94 8.3 0.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Spc24 PF08286.11 EEQ33715.1 - 1.8 8.8 7.1 1.5 9.1 0.5 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CENP-H PF05837.12 EEQ33715.1 - 3.7 8.0 10.3 1.7 9.1 0.6 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ATG27 PF09451.10 EEQ33716.1 - 8.9e-87 291.3 0.1 1.1e-86 291.0 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EEQ33716.1 - 5e-05 23.4 0.0 0.0097 16.0 0.1 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF1242 PF06842.12 EEQ33716.1 - 0.019 14.8 0.8 0.2 11.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1242) Sulfotransfer_3 PF13469.6 EEQ33717.1 - 0.1 13.0 0.1 27 5.0 0.1 3.0 2 1 0 2 2 2 0 Sulfotransferase family AAA_2 PF07724.14 EEQ33720.1 - 1.5e-45 155.4 0.0 1.6e-43 148.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EEQ33720.1 - 1.1e-32 112.0 1.5 1.1e-32 112.0 1.5 3.8 3 1 1 4 4 4 1 AAA lid domain AAA PF00004.29 EEQ33720.1 - 9.3e-27 94.0 0.0 4.9e-15 56.1 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EEQ33720.1 - 2.6e-22 78.7 0.9 7.4e-22 77.2 0.1 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EEQ33720.1 - 6.2e-15 55.4 0.6 5.8e-08 32.8 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEQ33720.1 - 7.1e-15 55.8 0.1 8e-07 29.6 0.0 4.7 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EEQ33720.1 - 1e-12 48.5 0.1 0.0001 22.6 0.0 4.2 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EEQ33720.1 - 3.4e-09 36.6 0.0 5.2e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 EEQ33720.1 - 3.2e-07 30.0 0.0 0.012 15.1 0.0 3.2 2 1 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 EEQ33720.1 - 5.6e-07 29.1 1.8 0.018 14.4 0.0 5.0 4 2 1 5 5 4 1 Bacterial TniB protein AAA_14 PF13173.6 EEQ33720.1 - 1.9e-06 27.9 0.0 0.028 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EEQ33720.1 - 2.1e-06 27.6 0.0 0.099 12.4 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EEQ33720.1 - 8.2e-06 26.4 0.6 0.12 13.0 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EEQ33720.1 - 9.2e-06 25.9 0.0 0.26 11.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 EEQ33720.1 - 1.7e-05 24.9 4.4 0.32 10.9 0.1 4.6 4 2 0 4 4 3 2 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EEQ33720.1 - 2.9e-05 23.6 0.0 0.18 11.2 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EEQ33720.1 - 4.2e-05 23.9 0.0 0.58 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EEQ33720.1 - 6.1e-05 23.3 0.7 1.3 9.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EEQ33720.1 - 6.6e-05 23.5 8.0 0.21 12.0 0.0 4.3 4 0 0 4 4 4 1 AAA domain Clp_N PF02861.20 EEQ33720.1 - 7.6e-05 22.8 3.9 0.027 14.6 0.0 4.2 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component AAA_3 PF07726.11 EEQ33720.1 - 7.8e-05 22.5 0.0 0.68 9.8 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEQ33720.1 - 0.00013 21.8 1.3 3.6 7.3 0.8 4.5 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EEQ33720.1 - 0.00013 21.9 0.0 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EEQ33720.1 - 0.00015 21.5 0.0 0.5 10.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EEQ33720.1 - 0.00023 21.7 0.2 0.92 10.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.6 EEQ33720.1 - 0.00052 19.8 0.0 0.49 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EEQ33720.1 - 0.00061 19.7 0.0 0.73 9.7 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_19 PF13245.6 EEQ33720.1 - 0.0016 18.7 0.1 0.75 10.1 0.2 3.3 2 1 1 3 3 3 1 AAA domain Torsin PF06309.11 EEQ33720.1 - 0.0025 17.9 0.0 0.01 15.9 0.0 1.9 2 0 0 2 2 1 1 Torsin NTPase_1 PF03266.15 EEQ33720.1 - 0.0034 17.3 0.1 0.11 12.5 0.0 3.1 3 0 0 3 3 3 1 NTPase T2SSE PF00437.20 EEQ33720.1 - 0.0038 16.3 0.0 0.038 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EEQ33720.1 - 0.006 15.9 0.0 3 7.1 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin NACHT PF05729.12 EEQ33720.1 - 0.0063 16.5 0.0 0.37 10.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 EEQ33720.1 - 0.0067 16.1 0.0 6.9 6.5 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 EEQ33720.1 - 0.0081 16.1 0.0 7.3 6.5 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain Roc PF08477.13 EEQ33720.1 - 0.0099 16.1 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 EEQ33720.1 - 0.01 15.5 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EEQ33720.1 - 0.016 14.8 0.3 2.3 7.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 EEQ33720.1 - 0.017 15.1 0.0 2.9 7.8 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit MobB PF03205.14 EEQ33720.1 - 0.098 12.6 0.0 28 4.6 0.0 3.1 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 EEQ33720.1 - 0.13 12.3 0.0 3.9 7.6 0.1 3.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EEQ33720.1 - 0.13 12.0 0.1 19 5.0 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein KfrA_N PF11740.8 EEQ33720.1 - 9.3 7.0 14.2 1.6 9.5 0.1 3.2 3 0 0 3 3 2 0 Plasmid replication region DNA-binding N-term SNF2_N PF00176.23 EEQ33721.1 - 2.5e-62 210.6 0.0 4.2e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ33721.1 - 5.8e-14 52.4 0.0 1.4e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ33721.1 - 4.8e-11 43.0 0.0 1.8e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EEQ33721.1 - 0.015 14.5 0.0 0.038 13.2 0.0 1.6 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 EBP PF05241.12 EEQ33723.1 - 5e-59 198.7 11.1 5.8e-59 198.5 11.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2347 PF09804.9 EEQ33724.1 - 8.7e-102 340.5 0.0 1.3e-101 340.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EEQ33724.1 - 1.7e-61 207.9 0.2 2.4e-61 207.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 EEQ33724.1 - 6.4e-07 28.4 0.0 0.0032 16.2 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 EEQ33724.1 - 0.0078 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DinB_2 PF12867.7 EEQ33725.1 - 0.084 13.4 1.3 0.84 10.2 0.1 2.6 2 0 0 2 2 2 0 DinB superfamily ZapB PF06005.12 EEQ33725.1 - 0.61 10.6 17.0 1.2 9.6 3.8 3.2 2 1 0 2 2 2 0 Cell division protein ZapB Peptidase_S46 PF10459.9 EEQ33725.1 - 2.2 6.8 9.0 3.3 6.3 9.0 1.3 1 0 0 1 1 1 0 Peptidase S46 Tubulin_3 PF14881.6 EEQ33726.1 - 6.3e-82 273.6 0.0 1e-81 273.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EEQ33726.1 - 5e-42 142.9 0.0 1.1e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EEQ33726.1 - 8.8e-06 26.0 0.0 0.0027 17.9 0.0 2.7 3 0 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain HSP70 PF00012.20 EEQ33729.1 - 8.7e-63 212.4 4.2 1.7e-58 198.2 0.7 2.5 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EEQ33729.1 - 0.0062 15.4 0.6 0.019 13.8 0.1 2.1 2 1 0 2 2 2 1 MreB/Mbl protein Peptidase_S49_N PF08496.10 EEQ33729.1 - 2.1 8.4 5.4 6.6 6.8 5.4 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MFS_1 PF07690.16 EEQ33730.1 - 3.4e-26 92.0 57.4 1e-24 87.2 57.1 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily tRNA-synt_1c PF00749.21 EEQ33732.1 - 4e-97 324.9 0.1 6.8e-97 324.1 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EEQ33732.1 - 1.8e-30 106.1 0.0 5.6e-30 104.5 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PMT_4TMC PF16192.5 EEQ33733.1 - 0.1 12.2 5.3 0.14 11.8 5.3 1.1 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase WD40 PF00400.32 EEQ33734.1 - 3.5e-06 27.7 5.3 0.0018 19.1 0.9 3.8 3 1 0 3 3 3 2 WD domain, G-beta repeat PD40 PF07676.12 EEQ33734.1 - 0.043 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EEQ33734.1 - 0.1 12.9 0.0 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 EEQ33735.1 - 1.9e-48 165.2 51.0 6.6e-47 160.1 51.4 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ33735.1 - 8e-19 67.5 24.4 1.2e-18 66.9 24.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ33735.1 - 1.4e-14 53.8 28.9 1.6e-14 53.6 15.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EEQ33735.1 - 6.2e-05 22.5 13.8 6.2e-05 22.5 13.8 3.2 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Spore_YhaL PF14147.6 EEQ33735.1 - 0.00017 21.2 0.1 0.0005 19.7 0.1 1.8 1 0 0 1 1 1 1 Sporulation protein YhaL ATPgrasp_N PF18130.1 EEQ33736.1 - 5.8e-16 58.8 0.0 1.8e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EEQ33736.1 - 2e-10 40.5 0.0 7.1e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EEQ33736.1 - 3e-07 30.2 0.0 2.4e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EEQ33736.1 - 8.5e-05 22.6 0.0 0.0046 17.0 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.16 EEQ33736.1 - 0.039 13.3 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain GDPD PF03009.17 EEQ33737.1 - 8.9e-43 146.9 0.0 4.1e-42 144.7 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EEQ33737.1 - 4.6e-21 75.2 0.6 1.7e-06 28.5 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ33737.1 - 1.1e-13 51.4 0.9 0.00019 21.9 0.1 5.5 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ33737.1 - 2.5e-11 42.7 1.4 0.029 14.9 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EEQ33737.1 - 5.6e-11 42.5 0.6 0.13 12.7 0.0 5.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EEQ33737.1 - 7.5e-10 38.8 2.1 0.24 11.9 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat SPX PF03105.19 EEQ33737.1 - 0.0002 21.4 0.6 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 SPX domain Corona_nucleoca PF00937.18 EEQ33737.1 - 0.11 11.6 3.8 0.53 9.3 0.0 2.1 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Ank_2 PF12796.7 EEQ33738.1 - 1.4e-23 83.3 0.0 6.9e-09 36.2 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ33738.1 - 5.3e-20 71.5 0.4 0.00012 22.5 0.0 5.8 3 3 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ33738.1 - 1e-17 62.4 1.5 0.07 13.7 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EEQ33738.1 - 4.1e-17 61.8 2.5 0.00069 19.9 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EEQ33738.1 - 5.5e-14 52.0 1.2 0.0001 22.5 0.0 6.2 4 3 3 8 8 8 2 Ankyrin repeats (many copies) Helo_like_N PF17111.5 EEQ33738.1 - 2.4e-05 23.8 3.1 5.2e-05 22.7 3.1 1.6 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Fungal_trans PF04082.18 EEQ33739.1 - 1.4e-18 66.9 0.0 3.1e-17 62.5 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Kdo_hydroxy PF11004.8 EEQ33741.1 - 0.058 12.6 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase MFS_1 PF07690.16 EEQ33742.1 - 1.7e-44 152.2 34.1 1.7e-44 152.2 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ33742.1 - 6.6e-16 58.2 5.5 1.3e-15 57.2 5.5 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EEQ33742.1 - 4.4e-06 26.2 5.1 4.4e-06 26.2 5.1 3.0 1 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EEQ33742.1 - 8.3e-06 24.5 1.4 8.3e-06 24.5 1.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.18 EEQ33742.1 - 0.00064 18.6 3.9 0.052 12.3 0.3 3.1 3 1 0 3 3 3 2 Reduced folate carrier Alpha-amylase PF00128.24 EEQ33744.1 - 6.4e-26 91.7 0.0 1.7e-25 90.3 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EEQ33744.1 - 0.0004 18.7 0.9 0.64 8.1 0.0 3.0 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 DUF1939 PF09154.10 EEQ33744.1 - 0.061 13.5 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) DEAD PF00270.29 EEQ33745.1 - 4.1e-26 91.8 0.0 9.7e-26 90.6 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ33745.1 - 1.3e-22 80.3 0.0 3.6e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ33745.1 - 1.3e-06 28.5 0.0 3.8e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Aminopep PF10023.9 EEQ33745.1 - 0.16 11.3 0.4 0.31 10.4 0.4 1.4 1 0 0 1 1 1 0 Putative aminopeptidase Ribonuc_L-PSP PF01042.21 EEQ33746.1 - 2.5e-38 130.8 0.0 2.8e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GFA PF04828.14 EEQ33748.1 - 0.041 14.2 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme HLH PF00010.26 EEQ33749.1 - 6.9e-09 35.5 0.1 1.8e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HNH_2 PF13391.6 EEQ33750.1 - 7.9e-15 54.8 0.3 5.1e-14 52.1 0.2 2.4 2 0 0 2 2 2 1 HNH endonuclease Maf PF02545.14 EEQ33751.1 - 1.1e-38 132.6 0.0 2.6e-38 131.5 0.0 1.6 1 1 0 1 1 1 1 Maf-like protein Ebola_NP PF05505.12 EEQ33751.1 - 0.76 8.0 2.6 1.1 7.5 2.6 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein CybS PF05328.12 EEQ33752.1 - 5.8e-51 171.7 0.0 7.1e-51 171.4 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit ADH_zinc_N PF00107.26 EEQ33753.1 - 1.7e-22 79.8 0.0 2.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EEQ33753.1 - 1.1e-18 67.0 0.0 2.3e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EEQ33753.1 - 1.3e-10 42.4 0.0 2.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NPM1-C PF16276.5 EEQ33753.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain Peptidase_M16 PF00675.20 EEQ33754.1 - 8.6e-55 184.8 0.0 3.1e-54 183.0 0.1 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEQ33754.1 - 4.5e-40 137.6 0.0 9e-39 133.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain MFS_1 PF07690.16 EEQ33755.1 - 1.2e-28 100.1 53.7 7.8e-26 90.8 41.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nitroreductase PF00881.24 EEQ33756.1 - 4.3e-17 62.7 0.0 5.3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Epimerase PF01370.21 EEQ33757.1 - 2.4e-18 66.5 0.0 3.1e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EEQ33757.1 - 6e-12 45.6 0.0 1.2e-11 44.6 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EEQ33757.1 - 2.4e-09 36.6 0.0 3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EEQ33757.1 - 0.00029 20.1 0.1 0.35 10.0 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EEQ33757.1 - 0.00061 19.0 0.0 0.00093 18.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EEQ33757.1 - 0.0046 16.9 0.0 0.0073 16.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EEQ33757.1 - 0.0053 16.2 0.0 0.026 14.0 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 EEQ33757.1 - 0.016 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 KR domain Fibrillarin PF01269.17 EEQ33758.1 - 3e-104 347.1 0.0 3.6e-104 346.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EEQ33758.1 - 5.8e-06 26.2 0.0 9.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 EEQ33758.1 - 0.029 14.0 0.0 0.069 12.8 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EEQ33758.1 - 0.043 13.6 0.1 0.072 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3455 PF11937.8 EEQ33759.1 - 3.4e-44 151.0 0.0 4.4e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EEQ33759.1 - 9.9e-05 22.4 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) CASP_C PF08172.12 EEQ33760.1 - 2.3e-91 305.6 0.4 2.3e-91 305.6 0.4 3.1 3 1 0 3 3 3 1 CASP C terminal Vps39_2 PF10367.9 EEQ33761.1 - 2.4e-07 31.2 0.0 6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EEQ33761.1 - 0.09 12.4 0.0 9.4 5.7 0.0 2.3 2 0 0 2 2 2 0 CNH domain STAS_2 PF13466.6 EEQ33761.1 - 0.13 12.6 0.1 0.34 11.3 0.1 1.8 1 0 0 1 1 1 0 STAS domain PALP PF00291.25 EEQ33762.1 - 1.1e-60 205.6 0.2 1.7e-60 204.9 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 EEQ33762.1 - 4.5e-24 85.3 0.1 1.5e-23 83.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEQ33762.1 - 4e-18 65.3 0.0 1.2e-17 63.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EEQ33762.1 - 0.00032 20.4 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EEQ33762.1 - 0.0061 15.6 0.0 2 7.3 0.0 2.7 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase UBA_4 PF14555.6 EEQ33763.1 - 5.5e-11 42.1 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EEQ33763.1 - 6.5e-09 35.9 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain RR_TM4-6 PF06459.12 EEQ33763.1 - 0.19 11.5 2.5 0.3 10.9 2.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.14 EEQ33763.1 - 0.29 10.3 8.6 0.52 9.5 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Atg14 PF10186.9 EEQ33763.1 - 0.47 9.5 5.4 0.67 9.0 5.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pan3_PK PF18101.1 EEQ33764.1 - 2.3e-62 209.0 0.4 3.4e-62 208.5 0.4 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain LSM PF01423.22 EEQ33765.1 - 3.3e-20 71.6 1.0 4.2e-20 71.2 1.0 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EEQ33765.1 - 0.02 15.0 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain SM-ATX PF14438.6 EEQ33765.1 - 0.023 14.8 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain baeRF_family7 PF18849.1 EEQ33765.1 - 0.13 12.5 1.4 0.19 11.9 1.4 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 DUF4175 PF13779.6 EEQ33765.1 - 1.6 6.5 7.8 1.8 6.4 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Zn_clus PF00172.18 EEQ33767.1 - 0.49 10.6 11.6 1.4 9.1 11.6 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FKBP_N PF01346.18 EEQ33767.1 - 3.7 8.6 11.9 3.5 8.7 8.9 2.4 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Dioxygenase_C PF00775.21 EEQ33768.1 - 2e-43 147.9 0.0 2.7e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EEQ33768.1 - 4.2e-29 100.2 0.0 8e-29 99.3 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus DUF4198 PF10670.9 EEQ33768.1 - 0.12 12.8 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Ribosomal_L22 PF00237.19 EEQ33769.1 - 2.8e-40 136.7 0.1 3.7e-40 136.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e 2-Hacid_dh_C PF02826.19 EEQ33770.1 - 5.8e-57 191.9 0.0 8.7e-57 191.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ33770.1 - 9.1e-20 70.7 0.0 1.1e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EEQ33770.1 - 0.00038 20.7 0.1 0.0012 19.1 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EEQ33770.1 - 0.0051 16.9 0.0 0.0098 16.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_N PF08240.12 EEQ33771.1 - 4.9e-23 81.1 0.0 7.9e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EEQ33771.1 - 0.0031 17.1 0.3 0.0089 15.5 0.3 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus adh_short_C2 PF13561.6 EEQ33772.1 - 1.1e-40 139.6 0.4 1.5e-40 139.2 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ33772.1 - 1.4e-38 132.3 0.5 2.2e-38 131.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 EEQ33772.1 - 5.7e-09 35.4 0.0 1.1e-07 31.1 0.0 2.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.10 EEQ33772.1 - 7.6e-06 26.0 0.3 1.5e-05 25.0 0.3 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EEQ33773.1 - 3.3e-56 190.5 0.6 4.1e-56 190.1 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ33773.1 - 1.4e-53 181.3 0.2 1.7e-53 181.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ33773.1 - 1.5e-13 51.0 0.7 2.5e-13 50.3 0.7 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ33773.1 - 9.5e-06 25.2 0.4 1.4e-05 24.7 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EEQ33773.1 - 2.3e-05 24.0 0.1 3.6e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_trans_4_4 PF13579.6 EEQ33773.1 - 0.00085 19.8 0.4 0.87 10.0 0.0 3.0 2 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EEQ33773.1 - 0.0093 15.7 0.0 0.021 14.5 0.0 1.6 2 0 0 2 2 2 1 Starch synthase catalytic domain THF_DHG_CYH_C PF02882.19 EEQ33773.1 - 0.011 15.1 0.2 0.023 14.0 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 EEQ33773.1 - 0.049 13.3 0.2 0.23 11.1 0.1 1.8 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Ferric_reduct PF01794.19 EEQ33774.1 - 1.4e-25 89.8 8.6 1.4e-25 89.8 8.6 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EEQ33774.1 - 3.7e-16 59.6 0.0 1.5e-13 51.1 0.0 2.8 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EEQ33774.1 - 3.2e-10 40.0 0.0 1.7e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 EEQ33774.1 - 0.13 13.0 0.0 0.46 11.1 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain GAT PF03127.14 EEQ33775.1 - 1.6e-16 60.4 2.1 7.4e-16 58.2 0.1 2.9 3 0 0 3 3 3 1 GAT domain VHS PF00790.19 EEQ33775.1 - 0.034 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 VHS domain Pyr_redox_2 PF07992.14 EEQ33776.1 - 5.1e-38 131.0 0.0 1e-35 123.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ33776.1 - 9.8e-11 42.1 0.0 6.8e-09 36.2 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ33776.1 - 0.035 14.1 0.1 0.28 11.2 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EEQ33776.1 - 0.096 12.9 0.0 28 5.0 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain p450 PF00067.22 EEQ33778.1 - 6e-71 239.6 0.0 7e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.6 EEQ33779.1 - 0.017 14.8 0.7 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MPS-4 PF17523.2 EEQ33779.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Zn_clus PF00172.18 EEQ33780.1 - 0.00081 19.5 9.0 0.0017 18.4 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EEQ33780.1 - 0.0071 15.2 0.1 0.09 11.6 0.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Plug_translocon PF10559.9 EEQ33781.1 - 0.079 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Plug domain of Sec61p Aminotran_1_2 PF00155.21 EEQ33784.1 - 1.1e-17 64.3 0.0 2.7e-14 53.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II PS_Dcarbxylase PF02666.15 EEQ33785.1 - 1.3e-54 184.8 0.0 2e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EEQ33785.1 - 1.6e-37 127.9 0.0 1.9e-17 63.4 0.1 2.8 2 0 0 2 2 2 2 C2 domain EF-hand_5 PF13202.6 EEQ33785.1 - 0.0075 15.7 0.0 0.021 14.3 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EEQ33785.1 - 0.036 13.6 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 EF hand AhpC-TSA_2 PF13911.6 EEQ33785.1 - 0.079 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme ThrE PF06738.12 EEQ33786.1 - 7.3e-66 222.0 15.9 3.9e-63 213.1 0.5 2.5 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EEQ33786.1 - 7.2e-09 35.9 11.5 7.2e-09 35.9 11.5 3.1 3 1 0 3 3 3 2 Threonine/Serine exporter, ThrE EBV-NA3 PF05009.12 EEQ33786.1 - 0.062 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Hydrolase_3 PF08282.12 EEQ33787.1 - 1.8e-11 44.3 0.0 2.3e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PMM PF03332.13 EEQ33787.1 - 4.1e-09 36.5 0.0 8.4e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.13 EEQ33787.1 - 0.00045 19.8 0.0 0.004 16.7 0.0 2.2 2 1 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EEQ33787.1 - 0.021 15.1 0.4 0.3 11.4 0.1 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ33787.1 - 0.11 12.6 0.0 1.8 8.6 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ank_4 PF13637.6 EEQ33789.1 - 4.5e-13 49.4 0.2 4.6e-07 30.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ33789.1 - 2.5e-10 40.8 0.1 7.9e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEQ33789.1 - 2.8e-08 33.4 0.2 1.1e-05 25.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EEQ33789.1 - 4.6e-07 30.0 0.7 8.4e-06 26.0 0.0 3.1 3 1 1 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EEQ33789.1 - 7.1e-07 29.4 0.1 1.3e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) HALZ PF02183.18 EEQ33789.1 - 0.55 10.5 4.5 2.3 8.5 1.5 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper NDUF_B7 PF05676.13 EEQ33791.1 - 9.3e-30 102.2 6.2 1.2e-29 101.9 6.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCS PF03074.16 EEQ33792.1 - 7.4e-175 581.6 0.0 1e-174 581.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.11 EEQ33792.1 - 0.038 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) CBS PF00571.28 EEQ33793.1 - 1.2e-21 76.8 0.8 4e-07 30.4 0.0 5.4 5 0 0 5 5 5 5 CBS domain Kdo PF06293.14 EEQ33795.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3435 PF11917.8 EEQ33796.1 - 7.1e-11 41.7 5.3 9.3e-11 41.3 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) MLD PF11647.8 EEQ33796.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 Membrane Localization Domain FliJ PF02050.16 EEQ33796.1 - 0.011 16.0 2.2 0.015 15.5 2.2 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein HEPN_AbiU2 PF18734.1 EEQ33796.1 - 0.1 12.1 0.6 0.14 11.6 0.6 1.2 1 0 0 1 1 1 0 AbiU2 DUF1682 PF07946.14 EEQ33796.1 - 0.27 10.4 4.1 0.36 10.0 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pkinase PF00069.25 EEQ33797.1 - 1.2e-22 80.5 0.0 1.2e-20 74.0 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain BST2 PF16716.5 EEQ33799.1 - 1.2 9.8 9.1 7.5 7.2 0.6 2.8 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 SlyX PF04102.12 EEQ33799.1 - 2.5 8.8 6.8 4.3 8.0 2.9 2.8 1 1 1 2 2 2 0 SlyX DUF2183 PF09949.9 EEQ33800.1 - 4.2e-33 113.6 0.0 1.7e-32 111.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EEQ33800.1 - 0.005 16.3 0.0 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) ADH_zinc_N_2 PF13602.6 EEQ33801.1 - 3.1e-19 70.3 0.0 5.2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EEQ33801.1 - 3.2e-05 23.9 0.0 5.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ33801.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain GPP34 PF05719.11 EEQ33802.1 - 6.4e-68 228.8 0.1 8e-68 228.5 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.25 EEQ33803.1 - 2.1e-11 44.0 0.1 3.1e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EEQ33803.1 - 0.00011 22.3 0.3 0.00018 21.7 0.3 1.3 1 1 0 1 1 1 1 Acyl-carrier AGP PF06376.12 EEQ33803.1 - 0.13 12.1 0.6 0.31 10.9 0.6 1.6 1 0 0 1 1 1 0 Arabinogalactan peptide Fer4 PF00037.27 EEQ33804.1 - 1.7e-13 49.7 16.5 6.2e-08 32.1 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EEQ33804.1 - 1.6e-12 47.8 10.0 2.5e-12 47.2 10.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EEQ33804.1 - 9.1e-10 39.3 9.9 0.00012 23.0 0.9 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EEQ33804.1 - 1.6e-09 37.7 31.3 6.1e-06 26.3 12.2 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 EEQ33804.1 - 1.7e-08 34.7 2.5 0.00037 20.9 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EEQ33804.1 - 2.3e-08 34.0 21.0 4.2e-06 26.8 12.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EEQ33804.1 - 3.4e-08 33.5 9.6 7.1e-08 32.5 9.7 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EEQ33804.1 - 1.6e-06 27.9 17.1 0.0004 20.3 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EEQ33804.1 - 5e-06 26.3 11.8 0.01 15.9 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EEQ33804.1 - 9.4e-06 25.7 11.4 0.0003 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EEQ33804.1 - 0.00041 20.8 11.7 0.044 14.3 12.6 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EEQ33804.1 - 0.01 16.0 5.6 0.49 10.7 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 EEQ33804.1 - 0.06 13.9 14.8 0.76 10.4 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EEQ33804.1 - 0.093 12.9 9.0 1.2 9.3 1.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EEQ33804.1 - 0.16 12.1 5.9 0.58 10.3 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 EEQ33804.1 - 0.25 12.4 15.5 0.43 11.6 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EEQ33804.1 - 1.1 10.2 12.1 2.3 9.1 1.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain SURF6 PF04935.12 EEQ33805.1 - 1e-50 172.3 29.1 1e-50 172.3 29.1 3.8 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 EEQ33805.1 - 5.4e-18 65.3 0.5 5.4e-18 65.3 0.5 8.3 8 2 0 8 8 8 2 60S ribosome biogenesis protein Rrp14 Rick_17kDa_Anti PF05433.15 EEQ33806.1 - 0.0041 17.0 17.6 0.0041 17.0 17.6 2.1 3 0 0 3 3 3 1 Glycine zipper 2TM domain DUF456 PF04306.13 EEQ33806.1 - 0.99 9.7 5.9 1.3 9.3 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Acyl_transf_3 PF01757.22 EEQ33808.1 - 1.6e-39 135.9 30.6 1.9e-39 135.7 30.6 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.15 EEQ33809.1 - 7e-13 49.0 0.2 1.4e-12 48.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ribosomal_S2 PF00318.20 EEQ33810.1 - 3.7e-66 222.5 0.0 3e-65 219.5 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S2 Mito_carr PF00153.27 EEQ33812.1 - 1.4e-51 172.3 0.4 1.8e-19 69.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.27 EEQ33813.1 - 2.3e-32 112.1 5.3 9.9e-31 106.8 5.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EEQ33813.1 - 8.2e-28 96.6 3.5 9.1e-28 96.5 1.3 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EEQ33813.1 - 8.8e-11 41.9 0.1 2.1e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 EEQ33813.1 - 7.6e-09 35.3 0.0 2.2e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.21 EEQ33813.1 - 0.00016 21.2 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EEQ33813.1 - 0.0002 20.8 0.1 0.00046 19.7 0.1 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 EEQ33813.1 - 0.00036 20.9 0.6 0.35 11.3 0.1 3.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EEQ33813.1 - 0.00054 19.9 3.3 0.023 14.6 0.2 2.5 1 1 1 2 2 2 1 RsgA GTPase Roc PF08477.13 EEQ33813.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EEQ33813.1 - 0.017 15.2 0.2 5.9 6.9 0.0 3.3 2 1 1 3 3 3 0 Dynamin family FeoB_N PF02421.18 EEQ33813.1 - 0.021 14.4 0.3 0.065 12.8 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Ras PF00071.22 EEQ33813.1 - 0.022 14.4 0.2 0.039 13.5 0.2 1.4 1 0 0 1 1 1 0 Ras family PduV-EutP PF10662.9 EEQ33813.1 - 0.038 13.7 0.3 0.1 12.3 0.3 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation zinc-ribbons_6 PF07191.12 EEQ33813.1 - 0.059 13.4 1.6 0.13 12.3 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbons GTP_EFTU_D4 PF14578.6 EEQ33813.1 - 0.093 12.6 2.0 0.28 11.1 0.1 2.8 3 1 0 3 3 2 0 Elongation factor Tu domain 4 DZR PF12773.7 EEQ33813.1 - 0.14 12.3 0.6 0.34 11.0 0.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon HNH PF01844.23 EEQ33815.1 - 0.012 15.8 2.8 0.028 14.6 2.8 1.7 1 1 0 1 1 1 0 HNH endonuclease HNH_5 PF14279.6 EEQ33815.1 - 0.059 13.2 0.8 0.54 10.2 0.8 2.1 1 1 0 1 1 1 0 HNH endonuclease EI24 PF07264.11 EEQ33816.1 - 7.2e-09 36.1 13.3 2.1e-08 34.6 13.3 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) COA2 PF17051.5 EEQ33816.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 Ceramidase_alk PF04734.13 EEQ33818.1 - 2.9e-203 676.1 0.0 3.4e-203 675.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EEQ33818.1 - 8.7e-60 201.4 0.0 1.3e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal BCAS2 PF05700.11 EEQ33819.1 - 2.1e-64 217.0 1.6 2.4e-64 216.8 1.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Kelch_5 PF13854.6 EEQ33820.1 - 2.5e-16 59.2 13.2 3e-08 33.5 0.1 5.0 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EEQ33820.1 - 2e-12 46.9 6.9 0.013 15.5 0.0 6.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EEQ33820.1 - 1.7e-10 40.8 9.1 0.075 13.3 0.2 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 EEQ33820.1 - 1.3e-09 38.1 7.2 0.00035 20.8 0.1 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EEQ33820.1 - 1.5e-05 24.5 8.4 0.058 13.0 0.4 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 EEQ33820.1 - 9.5e-05 22.2 2.7 0.32 11.0 0.2 4.3 4 0 0 4 4 4 1 Kelch motif Ten1 PF12658.7 EEQ33821.1 - 2.6e-41 140.4 0.0 3.1e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 EEQ33821.1 - 0.00037 20.2 0.0 0.0011 18.7 0.0 1.7 1 1 0 2 2 2 1 Telomere-capping, CST complex subunit Snf7 PF03357.21 EEQ33823.1 - 5.2e-33 114.1 16.2 5.2e-33 114.1 16.2 2.0 1 1 1 2 2 2 1 Snf7 Pecanex_C PF05041.15 EEQ33823.1 - 0.0046 16.6 0.5 0.0066 16.1 0.5 1.2 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Allexi_40kDa PF05549.11 EEQ33823.1 - 0.51 9.8 7.1 0.54 9.7 6.2 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein HTH_WhiA PF02650.14 EEQ33823.1 - 0.84 10.0 7.3 0.19 12.1 0.7 2.6 2 1 0 2 2 2 0 WhiA C-terminal HTH domain DUF3138 PF11336.8 EEQ33823.1 - 2.3 6.8 6.5 2.6 6.5 5.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) ARA70 PF12489.8 EEQ33823.1 - 3.4 7.9 7.8 2.1 8.6 4.9 2.0 1 1 1 2 2 2 0 Nuclear coactivator Forkhead PF00250.18 EEQ33824.1 - 3.6e-18 65.6 0.0 6.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EEQ33824.1 - 0.00013 22.3 0.0 0.00024 21.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_3 PF13640.6 EEQ33825.1 - 5.1e-10 40.1 0.0 7.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily cNMP_binding PF00027.29 EEQ33826.1 - 7.2e-40 135.0 0.0 3e-20 72.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain AMPK1_CBM PF16561.5 EEQ33827.1 - 1.6e-17 63.5 0.0 3.8e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EEQ33827.1 - 0.015 15.7 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) YjzC PF14168.6 EEQ33827.1 - 0.11 12.9 2.6 18 5.7 0.1 3.4 3 0 0 3 3 3 0 YjzC-like protein Ferric_reduct PF01794.19 EEQ33828.1 - 1.6e-14 54.1 8.3 1.6e-14 54.1 8.3 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EEQ33828.1 - 9.2e-13 48.2 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EEQ33828.1 - 9e-12 45.4 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Mito_carr PF00153.27 EEQ33829.1 - 1.7e-40 136.8 8.4 4.3e-16 58.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.12 EEQ33830.1 - 5.4e-25 87.4 5.7 8.6e-25 86.7 5.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ33830.1 - 5.8e-13 49.0 0.0 9.4e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EEQ33830.1 - 0.00075 18.9 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EEQ33830.1 - 0.0033 17.2 0.1 0.0053 16.5 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 EEQ33830.1 - 0.015 14.6 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EEQ33830.1 - 0.049 14.7 0.0 0.088 13.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ephrin_rec_like PF07699.13 EEQ33830.1 - 0.4 10.5 2.3 0.87 9.4 0.3 2.3 3 0 0 3 3 3 0 Putative ephrin-receptor like Abhydrolase_1 PF00561.20 EEQ33831.1 - 2.9e-25 89.4 0.1 6.7e-25 88.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ33831.1 - 1.2e-17 65.3 0.9 1.9e-17 64.6 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ33831.1 - 3.2e-06 26.6 0.0 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 EEQ33831.1 - 0.049 12.3 0.0 0.17 10.6 0.0 1.7 2 0 0 2 2 2 0 Ndr family Sugar_tr PF00083.24 EEQ33832.1 - 3.1e-73 247.2 21.5 1.7e-37 129.3 5.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EEQ33832.1 - 2.9e-23 82.4 45.8 2.4e-17 62.9 21.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EEQ33832.1 - 0.0064 14.8 4.4 0.54 8.5 0.2 2.7 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2306 PF10067.9 EEQ33833.1 - 9.3e-16 58.4 2.5 9.3e-16 58.4 2.5 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 EEQ33833.1 - 0.00039 20.7 5.6 0.0094 16.2 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF420) APH PF01636.23 EEQ33834.1 - 7.7e-11 42.4 0.0 1.1e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ33834.1 - 4.6e-05 22.5 0.3 0.0059 15.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 EEQ33834.1 - 0.01 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase RLL PF10036.9 EEQ33836.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein GST_C PF00043.25 EEQ33837.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF5568 PF17724.1 EEQ33838.1 - 0.12 12.2 0.2 0.15 11.9 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5568) EIIBC-GUT_N PF03612.14 EEQ33838.1 - 0.15 11.8 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SOG2 PF10428.9 EEQ33839.1 - 4.2 6.4 7.2 5.3 6.1 7.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein NADHdh_A3 PF14987.6 EEQ33840.1 - 0.0066 16.7 0.2 0.0085 16.4 0.2 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 DDOST_48kD PF03345.14 EEQ33841.1 - 4.1e-159 529.9 0.0 4.7e-159 529.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta MalF_P2 PF14785.6 EEQ33841.1 - 0.12 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Pet191_N PF10203.9 EEQ33842.1 - 1.5e-27 95.7 6.8 1.9e-27 95.4 6.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 EEQ33842.1 - 0.0084 16.1 4.5 1.4 9.0 0.5 2.3 2 0 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EEQ33842.1 - 0.0088 16.0 10.8 0.23 11.5 2.0 2.7 1 1 2 3 3 3 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COBRA PF04833.15 EEQ33842.1 - 0.016 15.2 0.6 0.02 14.8 0.6 1.2 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 EEQ33842.1 - 0.022 14.5 0.3 0.044 13.6 0.3 1.5 1 0 0 1 1 1 0 PAN-like domain Abhydrolase_1 PF00561.20 EEQ33843.1 - 5.9e-24 85.1 0.2 4.8e-23 82.1 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EEQ33843.1 - 2.7e-23 81.3 0.0 5.3e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.13 EEQ33843.1 - 9.7e-05 22.1 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EEQ33843.1 - 0.00022 20.6 0.0 0.012 14.9 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EEQ33843.1 - 0.18 11.6 0.3 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ras PF00071.22 EEQ33845.1 - 4.3e-29 101.2 0.3 1.2e-28 99.8 0.3 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EEQ33845.1 - 1.9e-05 24.8 0.4 0.00018 21.7 0.4 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ33845.1 - 4.5e-05 23.0 0.0 0.0002 20.9 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EEQ33845.1 - 0.0011 18.9 1.3 1.1 9.1 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EEQ33845.1 - 0.061 12.8 0.1 2.2 7.8 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Carboxyl_trans PF01039.22 EEQ33846.1 - 1.5e-139 465.9 0.0 1.9e-139 465.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EEQ33846.1 - 0.037 13.5 0.0 8.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 EEQ33846.1 - 0.049 12.9 0.9 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Acyl-CoA_dh_1 PF00441.24 EEQ33847.1 - 2.3e-39 135.0 0.2 5e-39 133.9 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EEQ33847.1 - 4.5e-35 120.7 0.1 1e-34 119.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EEQ33847.1 - 5.4e-27 93.8 0.1 1e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EEQ33847.1 - 1.1e-14 54.9 0.3 2.2e-14 53.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EEQ33847.1 - 0.00035 20.3 0.3 0.00087 19.0 0.3 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CPSase_L_D2 PF02786.17 EEQ33849.1 - 1.8e-73 246.6 0.0 2.6e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EEQ33849.1 - 2.3e-36 124.2 0.0 5.1e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EEQ33849.1 - 3.4e-35 120.9 0.0 7.4e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EEQ33849.1 - 6.9e-15 54.6 3.5 7.7e-15 54.5 2.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EEQ33849.1 - 1.4e-09 37.8 0.0 3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EEQ33849.1 - 4.2e-08 32.9 0.0 8.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EEQ33849.1 - 1.3e-05 24.9 0.3 0.12 12.2 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EEQ33849.1 - 0.00025 21.1 0.0 0.00055 20.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EEQ33849.1 - 0.0017 19.1 0.2 0.82 10.4 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 EEQ33849.1 - 0.005 16.6 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 EEQ33849.1 - 0.0053 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 EEQ33849.1 - 0.0084 16.0 0.2 0.024 14.5 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein ATP-grasp_4 PF13535.6 EEQ33849.1 - 0.045 13.4 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain HlyD_D23 PF16576.5 EEQ33849.1 - 0.093 11.9 0.1 4.7 6.4 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion adh_short_C2 PF13561.6 EEQ33850.1 - 9.6e-52 175.9 0.0 1.2e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ33850.1 - 3.1e-35 121.4 0.0 4.8e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ33850.1 - 2.3e-11 43.9 0.1 3.4e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EEQ33850.1 - 0.027 13.9 0.0 3.5 6.9 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Coatomer_E PF04733.14 EEQ33850.1 - 0.094 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit DUF1752 PF08550.10 EEQ33852.1 - 1.8e-10 40.5 3.5 3.7e-10 39.4 3.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SSP160 PF06933.11 EEQ33852.1 - 1.6 6.9 9.4 2.2 6.4 9.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF5327 PF17261.2 EEQ33852.1 - 8 7.3 7.0 1.9 9.3 1.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5327) MARVEL PF01284.23 EEQ33853.1 - 1.4e-09 38.1 3.6 2.3e-09 37.4 3.6 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF2339 PF10101.9 EEQ33853.1 - 0.016 13.8 0.5 0.018 13.7 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) TFIIA PF03153.13 EEQ33854.1 - 0.028 14.4 18.4 0.048 13.7 18.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRIMA1 PF16101.5 EEQ33854.1 - 4.5 7.3 8.8 9 6.4 3.4 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 ANAPC15 PF15243.6 EEQ33855.1 - 7.5 7.0 7.4 13 6.2 7.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 PHD PF00628.29 EEQ33856.1 - 2.8e-10 39.9 1.1 6.4e-10 38.8 1.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEQ33856.1 - 0.00034 20.1 2.3 0.00054 19.5 2.3 1.3 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EEQ33856.1 - 0.25 11.4 1.6 0.66 10.0 1.6 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger UIM PF02809.20 EEQ33856.1 - 0.39 10.8 3.3 0.94 9.5 3.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Glyco_hydro_18 PF00704.28 EEQ33860.1 - 1.4e-50 172.9 0.0 1.9e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EEQ33860.1 - 4e-08 33.6 30.1 4.9e-06 26.9 8.1 4.2 5 0 0 5 5 5 2 Chitin recognition protein Peptidase_M26_C PF07580.14 EEQ33860.1 - 0.17 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region MFS_1 PF07690.16 EEQ33861.1 - 5.6e-21 74.8 44.8 5.6e-15 55.1 37.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily P22_Cro PF14549.6 EEQ33861.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro NAD_binding_10 PF13460.6 EEQ33862.1 - 0.053 13.4 0.2 5 7.0 0.0 2.8 3 0 0 3 3 3 0 NAD(P)H-binding Epimerase PF01370.21 EEQ33862.1 - 0.058 12.8 0.0 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family LpxI_N PF17930.1 EEQ33862.1 - 0.063 13.2 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 LpxI N-terminal domain RmlD_sub_bind PF04321.17 EEQ33862.1 - 0.13 11.3 0.0 0.5 9.4 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 EEQ33863.1 - 1.4e-37 129.3 0.0 3.7e-37 128.0 0.0 1.8 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EEQ33863.1 - 1.5e-33 116.1 0.0 1.5e-32 112.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EEQ33863.1 - 0.00065 19.2 0.0 0.0021 17.6 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EEQ33863.1 - 0.00077 19.8 0.3 0.002 18.5 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EEQ33863.1 - 0.044 13.2 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase F-box-like_2 PF13013.6 EEQ33864.1 - 0.0015 18.5 0.0 0.003 17.5 0.0 1.6 1 1 0 1 1 1 1 F-box-like domain DUF5382 PF17354.2 EEQ33864.1 - 0.094 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5382) eIF-5a PF01287.20 EEQ33865.1 - 7.8e-05 22.7 0.1 0.00017 21.6 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.8 EEQ33865.1 - 1.6 9.4 7.7 0.2 12.3 0.4 2.4 1 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red MFS_1 PF07690.16 EEQ33866.1 - 8.8e-31 107.1 16.8 8.8e-31 107.1 16.8 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ33866.1 - 0.00018 20.5 5.7 0.00018 20.5 5.7 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EEQ33866.1 - 0.3 9.3 4.4 0.17 10.1 1.2 1.9 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CPP1-like PF11833.8 EEQ33866.1 - 0.68 9.6 6.4 0.15 11.7 2.0 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MFS_1_like PF12832.7 EEQ33866.1 - 0.96 8.2 12.1 0.84 8.4 0.4 2.4 2 1 1 3 3 3 0 MFS_1 like family YhhN PF07947.14 EEQ33867.1 - 9.8e-44 149.2 3.4 1.4e-43 148.7 3.4 1.2 1 0 0 1 1 1 1 YhhN family TMEM213 PF15192.6 EEQ33867.1 - 0.16 12.0 0.5 0.46 10.5 0.5 1.8 1 0 0 1 1 1 0 TMEM213 family Abhydrolase_1 PF00561.20 EEQ33869.1 - 1.5e-19 70.7 0.0 8.3e-19 68.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ33869.1 - 1.2e-17 65.2 6.5 6.2e-17 62.9 6.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ33869.1 - 3.1e-09 36.4 0.1 8.4e-09 35.0 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EEQ33869.1 - 0.009 15.5 0.0 0.048 13.1 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 EEQ33869.1 - 0.024 14.3 0.1 0.11 12.2 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 EEQ33869.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme 3-alpha PF03475.14 EEQ33869.1 - 0.084 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 3-alpha domain SRR1 PF07985.12 EEQ33872.1 - 2.9e-17 62.4 0.1 6e-17 61.4 0.1 1.6 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.7 EEQ33872.1 - 0.082 13.0 0.4 0.17 12.0 0.4 1.5 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF4050 PF13259.6 EEQ33873.1 - 0.029 14.7 0.1 0.045 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) TFIIA PF03153.13 EEQ33874.1 - 0.015 15.3 45.1 0.098 12.6 11.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_17 PF00332.18 EEQ33875.1 - 2.3e-09 37.3 3.5 2.9e-06 27.1 1.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Scytalone_dh PF02982.14 EEQ33876.1 - 8.4e-63 210.9 1.1 1.5e-62 210.1 1.1 1.4 1 1 0 1 1 1 1 Scytalone dehydratase NAD_binding_10 PF13460.6 EEQ33877.1 - 4e-18 66.0 0.0 5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ33877.1 - 5.7e-06 26.0 0.2 1.1e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 EEQ33877.1 - 0.001 18.1 0.1 0.0017 17.4 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EEQ33877.1 - 0.025 13.8 0.0 0.064 12.4 0.0 1.7 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 EEQ33877.1 - 0.031 13.4 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EEQ33877.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Questin_oxidase PF14027.6 EEQ33878.1 - 6.4e-95 318.6 0.4 7.5e-95 318.3 0.4 1.0 1 0 0 1 1 1 1 Questin oxidase-like EthD PF07110.11 EEQ33879.1 - 5.2e-18 66.0 0.1 6.9e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EEQ33879.1 - 0.004 17.6 0.0 0.0069 16.8 0.0 1.4 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Imm9 PF15587.6 EEQ33879.1 - 0.0074 16.0 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Immunity protein 9 Ribosomal_L26 PF16906.5 EEQ33879.1 - 0.071 13.6 0.0 0.088 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal DUF4879 PF16219.5 EEQ33879.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4879) MFS_1 PF07690.16 EEQ33880.1 - 1.1e-42 146.2 50.6 1.1e-42 146.2 50.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Neurensin PF14927.6 EEQ33880.1 - 0.12 12.1 3.5 1.1 9.0 0.0 3.9 4 1 0 4 4 4 0 Neurensin DUF5337 PF17272.2 EEQ33880.1 - 0.93 9.4 3.9 2 8.3 2.2 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5337) p450 PF00067.22 EEQ33881.1 - 1.5e-18 66.8 0.0 2.1e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AflR PF08493.10 EEQ33882.1 - 1.3e-15 57.7 16.5 9.3e-15 54.9 16.5 2.3 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 EEQ33882.1 - 5.7e-05 23.2 10.5 0.00011 22.2 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_11 PF08241.12 EEQ33883.1 - 4.2e-10 40.1 0.0 7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ33883.1 - 4.9e-07 30.4 0.1 9.3e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ33883.1 - 1.6e-06 28.0 0.0 2.7e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ33883.1 - 1.1e-05 26.1 0.0 2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EEQ33883.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_23 PF13489.6 EEQ33883.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EEQ33883.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SnoaL_2 PF12680.7 EEQ33885.1 - 0.0018 18.9 0.0 0.0025 18.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 EEQ33886.1 - 1.2e-56 191.9 3.2 1.6e-56 191.5 3.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ33886.1 - 1.9e-51 174.3 3.6 2.3e-51 174.0 3.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ33886.1 - 1.1e-15 58.0 1.8 1.4e-15 57.7 1.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ33886.1 - 3.6e-05 23.3 0.2 6.8e-05 22.4 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EEQ33886.1 - 0.0033 16.8 0.0 0.005 16.2 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF460 PF04312.13 EEQ33886.1 - 0.022 14.5 0.2 0.056 13.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF460) 2-Hacid_dh_C PF02826.19 EEQ33886.1 - 0.12 11.7 0.4 0.3 10.4 0.2 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ketoacyl-synt PF00109.26 EEQ33887.1 - 1.6e-15 57.4 0.1 6.4e-09 35.8 0.0 2.2 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EEQ33887.1 - 1.5e-08 34.7 0.0 3.9e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain DHHC PF01529.20 EEQ33890.1 - 3.9e-26 91.7 4.6 3.9e-26 91.7 4.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase HemY_N PF07219.13 EEQ33890.1 - 0.27 11.5 0.0 0.27 11.5 0.0 2.4 3 0 0 3 3 3 0 HemY protein N-terminus DUF4834 PF16118.5 EEQ33890.1 - 2.1 9.3 0.0 2.1 9.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Fungal_trans PF04082.18 EEQ33891.1 - 2.2e-07 30.2 0.1 4.3e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ33891.1 - 2.1e-06 27.8 12.2 3.9e-06 26.9 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 EEQ33892.1 - 1.3e-28 96.8 14.8 0.001 19.0 0.3 11.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ33892.1 - 6.8e-25 85.8 13.2 0.00037 20.2 0.8 10.4 11 0 0 11 11 11 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ33892.1 - 2.4e-22 78.9 24.8 3.3e-21 75.3 1.9 6.1 6 1 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EEQ33892.1 - 7.2e-16 57.0 12.8 0.013 15.7 0.1 9.7 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ33892.1 - 1.3e-15 57.6 16.7 0.0025 18.3 0.0 7.9 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ33892.1 - 1.4e-14 54.1 28.1 5.3e-08 33.0 0.5 10.1 7 3 3 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ33892.1 - 1.4e-10 41.1 16.8 1.8 9.6 0.5 8.6 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ33892.1 - 2.9e-10 40.6 15.4 0.19 12.4 0.8 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ33892.1 - 3.2e-08 33.1 6.5 0.38 10.5 0.1 7.4 6 2 2 8 8 8 1 TPR repeat TPR_10 PF13374.6 EEQ33892.1 - 1.7e-07 30.8 22.7 0.0058 16.5 0.1 7.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ33892.1 - 1e-06 28.9 8.4 3.1 8.6 0.1 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ33892.1 - 4.2e-05 23.3 24.8 1.5 9.0 0.2 10.1 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ33892.1 - 0.00042 20.5 12.2 8.7 7.0 0.0 8.5 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_21 PF09976.9 EEQ33892.1 - 0.0028 17.4 1.6 5.6 6.6 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EEQ33892.1 - 0.0073 15.7 7.4 0.26 10.6 2.5 3.9 4 1 0 4 4 4 1 MalT-like TPR region SRP_TPR_like PF17004.5 EEQ33892.1 - 0.019 15.0 0.6 0.65 10.0 0.0 3.1 3 0 0 3 3 2 0 Putative TPR-like repeat TPR_4 PF07721.14 EEQ33892.1 - 0.037 14.6 11.3 1.6 9.6 1.1 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Ank_5 PF13857.6 EEQ33892.1 - 0.051 13.9 0.1 4.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF572 PF04502.13 EEQ33893.1 - 2.8e-68 231.0 11.7 3.3e-68 230.8 11.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF951 PF06107.11 EEQ33893.1 - 0.049 13.5 0.1 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) HypA PF01155.19 EEQ33893.1 - 0.072 13.1 0.5 2 8.4 0.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 EEQ33893.1 - 0.1 12.3 2.4 7.8 6.3 0.4 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-FCS PF06467.14 EEQ33893.1 - 0.12 12.4 3.6 0.75 9.8 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.13 EEQ33893.1 - 0.14 12.1 3.6 0.14 12.0 1.6 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF866) TF_Zn_Ribbon PF08271.12 EEQ33893.1 - 0.55 9.8 6.0 0.89 9.1 1.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 EEQ33893.1 - 0.76 9.6 3.6 1.2 9.0 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-3CxxC PF13695.6 EEQ33893.1 - 0.79 10.2 3.3 2.5 8.6 3.3 1.9 1 1 0 1 1 1 0 Zinc-binding domain zf-ACC PF17848.1 EEQ33893.1 - 2.4 8.3 5.5 3.4 7.8 0.8 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Zn_ribbon_SprT PF17283.2 EEQ33893.1 - 3.6 7.6 6.0 5.4 7.0 0.5 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain FAT PF02259.23 EEQ33894.1 - 1.9e-70 237.8 12.9 4.1e-70 236.7 12.9 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EEQ33894.1 - 1.3e-33 116.9 0.1 3.2e-33 115.6 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EEQ33894.1 - 1.4e-06 28.0 0.1 3.9e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 EEQ33894.1 - 0.18 12.2 0.2 43 4.7 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat B56 PF01603.20 EEQ33895.1 - 4.5e-153 510.1 7.1 2.1e-120 402.5 2.4 2.1 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Tau95 PF09734.9 EEQ33896.1 - 4.2e-37 128.1 0.2 9.1e-37 127.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EEQ33896.1 - 1.1e-34 119.4 1.3 1.1e-34 119.3 0.0 1.7 2 0 0 2 2 2 1 Tau95 Triple barrel domain VIR_N PF15912.5 EEQ33896.1 - 0.011 15.4 0.2 0.022 14.4 0.2 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Soyouz_module PF14313.6 EEQ33897.1 - 0.068 13.0 1.6 0.25 11.2 0.2 2.8 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) ATP-grasp_4 PF13535.6 EEQ33898.1 - 2.3e-12 46.8 0.0 1.4e-11 44.2 0.0 2.2 2 1 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EEQ33898.1 - 1.1e-08 34.9 0.0 3.8e-08 33.1 0.0 2.0 3 0 0 3 3 3 1 D-ala D-ala ligase C-terminus ATPgrasp_N PF18130.1 EEQ33898.1 - 1.9e-07 31.5 0.0 4.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_3 PF02655.14 EEQ33898.1 - 6.2e-05 23.1 0.0 0.00082 19.5 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EEQ33898.1 - 0.00016 21.3 0.0 0.00038 20.0 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 EEQ33898.1 - 0.006 16.4 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EEQ33898.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain PfkB PF00294.24 EEQ33899.1 - 8.1e-40 137.0 0.0 2.1e-39 135.7 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase p6 PF17548.2 EEQ33899.1 - 0.095 12.7 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Histone-like Protein p6 ECH_1 PF00378.20 EEQ33900.1 - 3.4e-37 128.1 0.1 7e-36 123.8 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EEQ33900.1 - 1.3e-18 67.6 0.0 2.2e-18 66.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MCM PF00493.23 EEQ33901.1 - 5.3e-104 346.2 0.1 1.1e-103 345.2 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EEQ33901.1 - 2.7e-36 124.2 0.9 5.3e-36 123.2 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEQ33901.1 - 7.8e-29 99.9 1.3 2e-28 98.6 1.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ33901.1 - 2.3e-16 60.2 0.4 5.6e-16 59.0 0.4 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ33901.1 - 8.9e-07 28.5 0.0 0.00014 21.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ33901.1 - 2.2e-05 24.5 0.0 4.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEQ33901.1 - 0.00088 19.1 0.1 0.0033 17.3 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 EEQ33901.1 - 0.0013 18.9 0.1 0.0055 16.9 0.1 2.0 1 0 0 1 1 1 1 Midasin AAA lid domain Sigma54_activat PF00158.26 EEQ33901.1 - 0.024 14.4 0.1 0.26 11.0 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Vps54 PF07928.12 EEQ33904.1 - 9.6e-51 171.7 0.2 3.8e-50 169.8 0.0 2.2 2 0 0 2 2 2 1 Vps54-like protein DUF2451 PF10474.9 EEQ33904.1 - 7.7e-08 32.4 0.1 5.4e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 EEQ33904.1 - 9e-06 25.2 0.4 2.8e-05 23.5 0.2 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Cytochrom_B562 PF07361.11 EEQ33904.1 - 0.02 15.6 0.2 0.059 14.0 0.2 1.8 1 0 0 1 1 1 0 Cytochrome b562 DUF4363 PF14276.6 EEQ33904.1 - 0.24 11.6 0.5 1.7 8.8 0.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) COG2 PF06148.11 EEQ33904.1 - 0.28 11.3 2.1 0.51 10.4 1.3 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Hid1 PF12722.7 EEQ33907.1 - 0 1043.1 0.0 0 1039.2 0.0 1.9 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EEQ33907.1 - 1.2e-87 294.9 0.0 1.3e-61 208.9 0.0 2.0 2 0 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein BC10 PF06726.12 EEQ33907.1 - 0.068 13.4 0.1 0.23 11.7 0.1 2.0 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 GDPD_2 PF13653.6 EEQ33908.1 - 0.59 10.7 0.2 0.59 10.7 0.2 2.5 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family Cupin_2 PF07883.11 EEQ33909.1 - 3.4e-06 26.7 0.0 5.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HAT_KAT11 PF08214.11 EEQ33910.1 - 3.1e-95 319.5 0.0 4e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein DUF2255 PF10012.9 EEQ33910.1 - 0.032 14.4 0.1 0.054 13.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) Cation_ATPase_C PF00689.21 EEQ33911.1 - 2.1e-38 131.9 17.0 1.2e-37 129.4 6.1 3.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EEQ33911.1 - 1.1e-35 122.7 1.2 1.1e-35 122.7 1.2 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EEQ33911.1 - 6.2e-22 78.9 0.3 1.9e-18 67.5 0.3 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ33911.1 - 4.4e-18 65.2 0.0 9.5e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EEQ33911.1 - 2.9e-11 42.9 0.0 6.8e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEQ33911.1 - 1.7e-06 27.9 0.4 4.8e-05 23.2 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EEQ33911.1 - 2.3e-05 24.2 9.3 0.0011 18.7 0.1 3.3 3 1 0 3 3 3 2 Predicted membrane protein (DUF2157) TMEM43 PF07787.12 EEQ33911.1 - 0.0049 16.3 3.8 1.7 8.0 0.2 3.1 3 0 0 3 3 3 2 Transmembrane protein 43 MgtE PF01769.16 EEQ33911.1 - 0.013 15.8 12.7 0.22 11.9 0.1 3.8 3 1 1 4 4 4 0 Divalent cation transporter Rnf-Nqr PF02508.14 EEQ33911.1 - 0.12 12.3 6.5 0.11 12.4 1.1 2.9 2 0 0 2 2 2 0 Rnf-Nqr subunit, membrane protein DUF3262 PF11660.8 EEQ33911.1 - 8.4 6.9 9.2 35 4.9 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) Glyco_transf_21 PF13506.6 EEQ33913.1 - 5.4e-13 48.8 0.0 4.5e-06 26.3 0.0 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EEQ33913.1 - 3.4e-06 27.1 0.0 7.6e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF2621 PF11084.8 EEQ33913.1 - 0.25 11.3 1.7 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) Ank_2 PF12796.7 EEQ33914.1 - 1e-13 51.7 0.2 3.7e-12 46.6 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EEQ33914.1 - 1.5e-11 44.2 0.3 7.9e-07 29.3 0.3 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EEQ33914.1 - 9e-10 38.6 1.0 3.4e-07 30.4 0.3 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ33914.1 - 1.3e-09 38.4 0.3 7.5e-09 36.0 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ33914.1 - 1.5e-09 37.3 0.1 1.2e-05 25.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat WW PF00397.26 EEQ33915.1 - 1.7e-09 37.6 1.0 1.7e-09 37.6 1.0 2.1 2 0 0 2 2 2 1 WW domain WRW PF10206.9 EEQ33915.1 - 0.085 13.2 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Hydrophobin PF01185.18 EEQ33916.1 - 1.4e-08 35.3 11.5 1.8e-08 34.9 11.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin PepSY_2 PF13670.6 EEQ33916.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain SRI PF08236.11 EEQ33916.1 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain SCP1201-deam PF14428.6 EEQ33917.1 - 0.045 13.6 1.5 1.3 8.9 0.3 2.4 2 0 0 2 2 2 0 SCP1.201-like deaminase NMO PF03060.15 EEQ33918.1 - 1.6e-57 195.4 0.3 8.9e-57 192.9 0.3 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EEQ33918.1 - 4.3e-14 52.3 0.0 4.9e-12 45.5 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EEQ33918.1 - 0.0011 18.1 0.7 0.002 17.2 0.7 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 EEQ33918.1 - 0.0099 15.1 0.1 0.022 13.9 0.1 1.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Sdh_cyt PF01127.22 EEQ33919.1 - 9.6e-24 83.7 4.1 1.6e-23 83.0 4.1 1.4 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribonucleas_3_3 PF14622.6 EEQ33920.1 - 2.9e-23 82.4 0.0 4.4e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EEQ33920.1 - 0.0082 16.7 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Adap_comp_sub PF00928.21 EEQ33921.1 - 7.8e-91 304.1 0.0 9.9e-91 303.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EEQ33921.1 - 3.5e-09 36.7 0.1 5.8e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EEQ33921.1 - 0.11 12.0 0.0 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain ABC2_membrane PF01061.24 EEQ33924.1 - 8.2e-77 257.4 46.2 3.4e-40 137.7 11.9 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EEQ33924.1 - 5.7e-34 117.6 0.0 2.2e-17 63.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EEQ33924.1 - 4.5e-22 77.8 5.3 1.2e-19 70.0 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EEQ33924.1 - 6.8e-12 45.8 0.0 6.4e-11 42.7 0.0 2.6 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EEQ33924.1 - 2.8e-06 26.7 37.0 0.0025 17.0 4.4 2.9 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 EEQ33924.1 - 1.5e-05 25.0 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EEQ33924.1 - 3.5e-05 24.3 0.0 0.0053 17.2 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EEQ33924.1 - 0.00048 20.3 0.0 0.012 15.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ33924.1 - 0.00087 19.8 0.0 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EEQ33924.1 - 0.001 18.8 0.4 0.015 15.1 0.1 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ33924.1 - 0.0014 18.6 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EEQ33924.1 - 0.0055 16.3 0.8 0.017 14.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EEQ33924.1 - 0.0076 16.5 0.1 0.13 12.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EEQ33924.1 - 0.0088 15.5 0.0 0.2 11.1 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ATP-grasp_5 PF13549.6 EEQ33924.1 - 0.08 12.4 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain CysA_C_terminal PF17850.1 EEQ33924.1 - 0.097 13.3 0.1 0.28 11.8 0.1 1.8 1 0 0 1 1 1 0 CysA C-terminal regulatory domain AAA_22 PF13401.6 EEQ33924.1 - 0.11 12.8 0.2 0.33 11.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EEQ33924.1 - 0.36 11.3 0.0 0.36 11.3 0.0 2.9 4 0 0 4 4 2 0 AAA domain MFS_1 PF07690.16 EEQ33925.1 - 1.3e-37 129.6 23.5 4.8e-37 127.7 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EEQ33925.1 - 1e-07 31.6 1.6 1e-07 31.6 1.6 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ABC_tran PF00005.27 EEQ33926.1 - 5.1e-50 169.5 0.0 8e-25 88.0 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 EEQ33926.1 - 2.1e-23 83.0 50.0 4.1e-14 52.5 26.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EEQ33926.1 - 9e-23 81.5 1.4 0.00014 21.8 0.0 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ33926.1 - 1.1e-09 38.1 0.9 0.00037 20.0 0.2 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ33926.1 - 7.5e-09 35.2 3.6 7.5e-05 22.4 0.4 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EEQ33926.1 - 1.6e-08 35.3 1.7 0.0022 18.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EEQ33926.1 - 4.8e-06 26.3 0.3 0.087 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EEQ33926.1 - 1.4e-05 25.0 0.1 0.044 13.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF4162 PF13732.6 EEQ33926.1 - 3.9e-05 24.3 0.1 0.0018 18.9 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 EEQ33926.1 - 4.1e-05 23.5 0.0 0.0092 15.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 EEQ33926.1 - 0.00056 19.7 0.7 0.35 10.5 0.1 2.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EEQ33926.1 - 0.00092 19.6 0.1 1.9 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 EEQ33926.1 - 0.015 15.6 0.1 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EEQ33926.1 - 0.025 14.6 0.3 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 EEQ33926.1 - 0.042 14.1 0.2 31 4.9 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 EEQ33926.1 - 0.053 13.2 0.6 8.4 6.0 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EEQ33926.1 - 0.096 11.9 0.7 12 5.1 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 EEQ33926.1 - 0.12 11.9 2.9 3.9 7.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EEQ33926.1 - 0.19 12.0 0.4 25 5.1 0.1 2.9 3 0 0 3 3 2 0 AAA domain Peptidase_M18 PF02127.15 EEQ33927.1 - 9.6e-134 446.4 0.0 1.2e-133 446.1 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EEQ33927.1 - 0.00049 19.2 0.0 0.18 10.8 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase PIN_6 PF17146.4 EEQ33928.1 - 3.2e-30 104.5 0.8 8.8e-30 103.1 0.0 2.2 3 0 0 3 3 3 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EEQ33928.1 - 3.6e-27 94.3 5.4 7.6e-27 93.3 3.8 2.0 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 EEQ33928.1 - 0.0059 16.2 0.6 0.0059 16.2 0.6 2.3 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 EEQ33928.1 - 0.012 15.6 1.9 1.1 9.4 0.3 3.2 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EEQ33928.1 - 0.83 9.8 5.0 0.64 10.2 1.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Nop10p PF04135.12 EEQ33929.1 - 3.6e-22 78.1 0.6 4.2e-22 77.9 0.6 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family tRNA_int_endo PF01974.17 EEQ33930.1 - 5.8e-18 64.7 0.2 1.6e-17 63.3 0.2 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EEQ33930.1 - 0.00011 21.7 0.0 0.026 14.2 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Rad9_Rad53_bind PF08605.10 EEQ33931.1 - 7.9e-16 58.4 0.0 1.4e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 EEQ33931.1 - 5.7e-14 51.7 0.0 1.1e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT PF00533.26 EEQ33931.1 - 5.6e-08 33.1 0.0 1e-06 29.0 0.0 2.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EEQ33931.1 - 4.7e-05 23.2 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EEQ33931.1 - 5.1e-05 23.6 0.0 0.00016 22.0 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 EEQ33931.1 - 0.073 13.2 0.1 0.56 10.3 0.0 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ribosomal_L27 PF01016.19 EEQ33932.1 - 9.4e-32 108.9 1.1 1.6e-31 108.1 1.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein RRN9 PF10680.9 EEQ33932.1 - 3 8.2 6.9 2.5 8.4 3.8 2.3 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor Scramblase PF03803.15 EEQ33934.1 - 1.2e-56 191.5 0.0 6.2e-55 185.9 0.0 2.7 1 1 0 1 1 1 1 Scramblase UQ_con PF00179.26 EEQ33935.1 - 2.1e-49 166.8 0.0 2.3e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TP6A_N PF04406.14 EEQ33936.1 - 9.2e-16 57.6 0.0 1.7e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Methyltransf_23 PF13489.6 EEQ33937.1 - 3.2e-10 40.1 0.0 7.8e-10 38.8 0.0 1.7 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ33937.1 - 1.6e-06 28.7 0.0 4.2e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ33937.1 - 0.00014 21.6 0.0 0.00085 19.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ33937.1 - 0.00019 22.1 0.0 0.0027 18.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EEQ33937.1 - 0.011 15.2 0.0 0.033 13.7 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 EEQ33937.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 EEQ33937.1 - 0.016 15.3 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 EEQ33937.1 - 0.02 14.4 0.0 0.089 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain DUF938 PF06080.12 EEQ33937.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_11 PF08241.12 EEQ33937.1 - 0.092 13.4 0.0 0.22 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain NADHdh-2_N PF12155.8 EEQ33937.1 - 0.094 13.1 0.5 0.16 12.3 0.1 1.6 2 0 0 2 2 1 0 NADH dehydrogenase subunit 2 N-terminal LAGLIDADG_2 PF03161.13 EEQ33938.1 - 0.088 12.8 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family DUF2263 PF10021.9 EEQ33939.1 - 1.6e-19 70.7 0.1 3.2e-19 69.8 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 EEQ33939.1 - 0.16 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Macro domain Pept_tRNA_hydro PF01195.19 EEQ33940.1 - 1.7e-23 83.4 0.0 7.9e-12 45.5 0.1 2.8 2 1 0 2 2 2 2 Peptidyl-tRNA hydrolase T3SS_ExsE PF18286.1 EEQ33940.1 - 0.066 13.2 0.1 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system ExsE Pkinase PF00069.25 EEQ33941.1 - 2.9e-55 187.5 0.0 1.5e-49 168.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ33941.1 - 1.3e-34 119.7 0.0 9.4e-33 113.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEQ33941.1 - 1.1e-08 34.7 0.0 2e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EEQ33941.1 - 0.0022 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEQ33941.1 - 0.0023 16.8 0.1 0.0098 14.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Sybindin PF04099.12 EEQ33942.1 - 2.8e-24 85.7 0.0 3.7e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EEQ33942.1 - 0.0078 16.3 0.8 0.013 15.7 0.7 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.25 EEQ33943.1 - 8e-50 169.7 0.0 1.3e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ33943.1 - 3.8e-27 95.2 0.0 5.5e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ33943.1 - 0.0078 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ33943.1 - 0.017 14.5 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like BAR PF03114.18 EEQ33944.1 - 1.1e-65 221.7 4.8 1.3e-65 221.4 4.8 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 EEQ33944.1 - 0.016 16.0 0.6 0.063 14.0 0.0 2.4 3 2 0 3 3 3 0 CP12 domain DUF2884 PF11101.8 EEQ33944.1 - 0.21 11.1 4.0 1.5 8.3 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2884) FliD_N PF02465.18 EEQ33944.1 - 2.7 8.8 6.0 25 5.6 0.2 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SRI PF08236.11 EEQ33947.1 - 2.4e-20 72.5 14.9 2.4e-20 72.5 14.9 2.3 1 1 1 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EEQ33947.1 - 1.1e-17 65.0 0.4 1.1e-17 65.0 0.4 3.3 3 1 0 3 3 3 1 SET domain AWS PF17907.1 EEQ33947.1 - 6.4e-10 38.9 13.5 6.4e-10 38.9 13.5 2.7 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 EEQ33947.1 - 1.3e-06 28.4 0.2 3.7e-06 26.8 0.2 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 EEQ33947.1 - 0.03 14.4 0.3 0.089 12.9 0.3 1.9 1 0 0 1 1 1 0 WW domain Pox_H7 PF04787.12 EEQ33947.1 - 0.42 11.1 3.9 0.83 10.2 3.9 1.4 1 0 0 1 1 1 0 Late protein H7 Brix PF04427.18 EEQ33949.1 - 9.3e-24 84.6 0.5 1.4e-23 84.0 0.1 1.5 2 0 0 2 2 2 1 Brix domain Na_trans_assoc PF06512.13 EEQ33949.1 - 0.5 10.6 7.7 0.77 10.0 7.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Hid1 PF12722.7 EEQ33949.1 - 2 6.4 6.9 2.7 6.0 6.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HGTP_anticodon PF03129.20 EEQ33950.1 - 3.6e-19 68.7 0.0 3.6e-19 68.7 0.0 2.8 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EEQ33950.1 - 4e-09 36.7 0.0 1.9e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.25 EEQ33952.1 - 5.2e-61 206.3 0.2 5.9e-60 202.9 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ33952.1 - 8.3e-48 162.9 0.1 1.7e-47 161.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EEQ33952.1 - 5.1e-24 84.4 0.0 5.1e-24 84.4 0.0 2.6 3 0 0 3 3 2 1 P21-Rho-binding domain PH_11 PF15413.6 EEQ33952.1 - 4.5e-15 56.0 0.1 1.2e-14 54.6 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 EEQ33952.1 - 2e-05 24.0 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ33952.1 - 2.8e-05 23.1 0.0 2.8e-05 23.1 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 EEQ33952.1 - 4.8e-05 22.5 0.1 0.00011 21.3 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain PH PF00169.29 EEQ33952.1 - 0.00013 22.4 0.1 0.00033 21.1 0.1 1.8 1 0 0 1 1 1 1 PH domain KIND PF16474.5 EEQ33952.1 - 0.027 14.4 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Seadorna_VP7 PF07387.11 EEQ33952.1 - 0.04 13.0 0.1 0.063 12.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EEQ33952.1 - 2 8.3 5.6 0.94 9.3 0.3 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DDRGK PF09756.9 EEQ33952.1 - 3.3 7.3 12.2 7 6.2 12.2 1.4 1 0 0 1 1 1 0 DDRGK domain NAD_kinase PF01513.21 EEQ33953.1 - 6.3e-48 163.5 0.0 1.1e-47 162.7 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EEQ33953.1 - 0.0061 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Acyltransferase PF01553.21 EEQ33954.1 - 1.1e-26 93.0 0.0 2.5e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase TPR_2 PF07719.17 EEQ33954.1 - 4.6e-23 79.4 17.8 0.0087 16.1 0.2 11.4 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ33954.1 - 3.9e-21 73.9 18.9 0.0013 18.5 0.2 11.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ33954.1 - 1.7e-18 66.9 24.4 0.00012 22.6 0.0 9.1 9 1 1 10 10 9 4 Tetratricopeptide repeat Acyltransf_C PF16076.5 EEQ33954.1 - 1.7e-13 50.5 0.7 4.4e-13 49.1 0.0 2.1 2 0 0 2 2 1 1 Acyltransferase C-terminus TPR_8 PF13181.6 EEQ33954.1 - 2e-12 46.3 20.3 0.22 11.8 0.1 11.3 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ33954.1 - 4.3e-12 45.8 23.1 0.049 14.5 0.0 11.3 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ33954.1 - 2e-09 37.6 21.3 0.009 16.3 0.9 8.3 7 2 1 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ33954.1 - 3.5e-06 27.6 21.5 0.091 13.4 0.5 8.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ33954.1 - 6.7e-06 25.8 6.7 3 8.1 0.0 8.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ33954.1 - 1.2e-05 25.7 23.0 0.13 12.9 0.1 11.1 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ33954.1 - 8.5e-05 22.2 23.8 0.052 13.2 0.2 8.4 9 0 0 9 9 9 2 TPR repeat TPR_17 PF13431.6 EEQ33954.1 - 0.00036 20.7 19.8 0.2 12.1 0.1 9.5 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ33954.1 - 0.013 15.3 0.3 0.013 15.3 0.3 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TOM20_plant PF06552.12 EEQ33954.1 - 0.079 12.7 0.7 1.9 8.2 0.0 3.0 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_3 PF07720.12 EEQ33954.1 - 1.7 8.7 9.1 46 4.1 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat SGL PF08450.12 EEQ33955.1 - 2.7e-28 99.2 1.6 8e-26 91.1 1.6 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EEQ33955.1 - 0.0005 20.1 0.0 0.011 15.9 0.0 3.0 3 1 0 3 3 3 1 Strictosidine synthase Arylesterase PF01731.20 EEQ33955.1 - 0.083 13.1 0.1 0.74 10.1 0.0 2.5 3 0 0 3 3 3 0 Arylesterase Zn_clus PF00172.18 EEQ33956.1 - 0.073 13.2 3.1 0.14 12.3 3.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Es2 PF09751.9 EEQ33960.1 - 1.7e-141 472.9 10.6 2.1e-141 472.6 10.6 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Anophelin PF10731.9 EEQ33960.1 - 0.054 13.3 1.6 0.13 12.1 1.6 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Mid1 PF12929.7 EEQ33961.1 - 5.3e-155 516.8 4.6 6.2e-155 516.6 4.6 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EEQ33961.1 - 0.00012 22.7 6.6 0.0076 16.9 2.7 2.4 2 0 0 2 2 2 2 Fz domain Colicin_E5 PF12106.8 EEQ33961.1 - 0.27 11.6 0.9 1.8 9.0 0.2 2.4 2 1 1 3 3 3 0 Colicin E5 ribonuclease domain CorA PF01544.18 EEQ33962.1 - 2.5e-41 141.9 0.0 3.5e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4597 PF15366.6 EEQ33962.1 - 0.077 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) YqcI_YcgG PF08892.11 EEQ33963.1 - 3.3e-65 219.9 0.1 4.4e-65 219.4 0.1 1.2 1 0 0 1 1 1 1 YqcI/YcgG family MFS_1 PF07690.16 EEQ33964.1 - 2.5e-30 105.6 44.8 2.7e-30 105.5 38.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ33964.1 - 8.1e-11 41.4 14.7 8.1e-11 41.4 14.7 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4267 PF14087.6 EEQ33964.1 - 0.13 12.3 3.5 0.19 11.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) TRI12 PF06609.13 EEQ33964.1 - 0.56 8.5 13.8 0.0083 14.6 6.1 1.8 3 0 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) SPC12 PF06645.13 EEQ33965.1 - 2e-18 66.2 3.2 8.2e-17 61.1 3.2 2.0 1 1 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) zf-rbx1 PF12678.7 EEQ33966.1 - 5.4e-25 87.4 12.5 7.7e-25 86.9 12.5 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EEQ33966.1 - 6.3e-17 61.4 9.8 8.2e-17 61.0 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EEQ33966.1 - 2.3e-06 27.8 14.7 8e-05 22.9 14.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ33966.1 - 5e-05 23.1 3.3 5e-05 23.1 3.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ33966.1 - 0.0026 17.6 11.7 0.045 13.6 11.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EEQ33966.1 - 0.11 12.6 8.9 0.56 10.4 9.0 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EEQ33966.1 - 0.41 10.5 10.8 0.83 9.6 4.4 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ33966.1 - 0.6 10.2 8.2 2.2 8.4 8.2 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EEQ33966.1 - 0.69 9.6 14.3 1e+02 2.6 14.3 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EEQ33966.1 - 1.1 9.0 17.1 1e+02 2.8 17.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger PNRC PF15365.6 EEQ33967.1 - 9.5e-09 34.8 7.7 9.5e-09 34.8 7.7 4.2 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif SMI1_KNR4 PF09346.10 EEQ33968.1 - 4.9e-33 114.3 0.0 8.3e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Thioredoxin PF00085.20 EEQ33969.1 - 0.00031 20.7 0.0 0.00088 19.2 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin DUF3496 PF12001.8 EEQ33969.1 - 0.064 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) Peptidase_M14 PF00246.24 EEQ33970.1 - 2.1e-80 270.7 0.0 9.5e-80 268.5 0.0 1.8 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EEQ33970.1 - 1.6e-09 38.0 0.4 7.8e-09 35.8 0.0 2.3 3 0 0 3 3 3 1 Carboxypeptidase activation peptide AstE_AspA PF04952.14 EEQ33970.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Methyltransf_25 PF13649.6 EEQ33971.1 - 3.7e-07 30.8 0.0 9e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ33971.1 - 2.2e-05 25.0 0.0 4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ33971.1 - 6.6e-05 22.8 0.0 9.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ33971.1 - 0.015 16.1 0.1 0.055 14.2 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 EEQ33971.1 - 0.015 15.1 0.0 0.048 13.4 0.0 1.8 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_31 PF13847.6 EEQ33971.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF4974 PF16344.5 EEQ33971.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) FSH1 PF03959.13 EEQ33972.1 - 8e-30 104.1 0.0 1.1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EEQ33972.1 - 0.023 14.5 0.2 1.2 8.8 0.3 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase ApoLp-III PF07464.11 EEQ33973.1 - 7.2e-05 22.9 6.7 7.2e-05 22.9 6.7 4.6 1 1 3 4 4 4 2 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 EEQ33973.1 - 0.0019 18.1 31.9 0.023 14.6 2.6 4.3 3 1 2 5 5 5 3 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 EEQ33973.1 - 0.0031 17.6 33.5 0.48 10.5 0.5 6.3 2 1 4 6 6 6 3 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EEQ33973.1 - 0.0096 16.0 39.8 0.2 11.7 4.1 6.5 2 1 6 8 8 8 3 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 EEQ33973.1 - 0.016 15.1 0.0 0.016 15.1 0.0 4.5 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Filament PF00038.21 EEQ33973.1 - 0.02 14.5 44.9 0.31 10.6 15.4 4.9 1 1 2 3 3 3 0 Intermediate filament protein DUF5082 PF16888.5 EEQ33973.1 - 0.098 12.9 36.9 5.3 7.4 0.1 7.0 4 3 2 6 6 6 0 Domain of unknown function (DUF5082) PIN_10 PF18478.1 EEQ33973.1 - 0.12 12.7 0.1 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 PIN like domain GIY-YIG PF01541.24 EEQ33973.1 - 0.31 11.3 1.3 25 5.3 0.0 3.4 4 0 0 4 4 3 0 GIY-YIG catalytic domain ETRAMP PF09716.10 EEQ33973.1 - 0.62 10.2 2.4 3 8.0 0.1 2.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Phasin_2 PF09361.10 EEQ33973.1 - 0.99 9.7 11.6 0.91 9.8 2.5 4.2 1 1 2 4 4 4 0 Phasin protein Syntaxin-6_N PF09177.11 EEQ33973.1 - 3.1 8.4 32.5 3.8 8.1 6.8 6.7 2 2 1 3 3 3 0 Syntaxin 6, N-terminal GrpE PF01025.19 EEQ33973.1 - 4 7.1 28.5 0.058 13.1 6.7 4.5 2 1 2 4 4 4 0 GrpE TipAS PF07739.13 EEQ33973.1 - 7.1 7.2 14.8 4.1 8.0 0.1 4.8 1 1 3 4 4 4 0 TipAS antibiotic-recognition domain TIP49 PF06068.13 EEQ33974.1 - 8.1e-154 512.0 1.7 1.2e-153 511.5 1.7 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EEQ33974.1 - 1.7e-21 76.1 0.8 7.6e-21 74.0 0.2 2.5 3 0 0 3 3 3 1 TIP49 AAA-lid domain AAA PF00004.29 EEQ33974.1 - 4.3e-08 33.6 0.2 5.8e-05 23.5 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEQ33974.1 - 1.8e-07 31.0 0.5 0.00018 21.3 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EEQ33974.1 - 1.5e-06 27.7 0.9 2.8e-06 26.9 0.9 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EEQ33974.1 - 1.6e-05 25.3 0.0 4.3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EEQ33974.1 - 0.0013 18.1 1.0 0.017 14.5 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ33974.1 - 0.0079 16.2 0.3 1.2 9.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ33974.1 - 0.016 15.5 0.0 0.96 9.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EEQ33974.1 - 0.025 14.3 0.0 8.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 EEQ33974.1 - 0.04 14.2 1.2 1 9.7 1.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EEQ33974.1 - 0.049 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEQ33974.1 - 0.05 13.2 0.1 0.093 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EEQ33974.1 - 0.092 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EEQ33974.1 - 0.095 12.5 0.5 0.32 10.7 0.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEQ33974.1 - 0.11 12.0 0.3 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region GYF PF02213.16 EEQ33975.1 - 2.2e-08 33.6 1.0 5.1e-08 32.5 1.0 1.6 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.14 EEQ33976.1 - 1.8e-74 248.9 0.0 2.4e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EEQ33976.1 - 0.12 12.2 0.0 1.8 8.4 0.0 2.2 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 DUF829 PF05705.14 EEQ33977.1 - 2.4e-51 175.0 0.0 2.8e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Neogenin_C PF06583.12 EEQ33980.1 - 0.05 13.4 0.2 0.061 13.1 0.2 1.1 1 0 0 1 1 1 0 Neogenin C-terminus DUF4366 PF14283.6 EEQ33981.1 - 0.034 14.2 0.5 0.18 11.8 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1477 PF07346.11 EEQ33981.1 - 0.12 12.7 0.3 0.18 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) Presenilin PF01080.17 EEQ33981.1 - 0.19 10.4 0.3 0.25 10.1 0.3 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 EEQ33981.1 - 0.23 10.3 6.0 0.27 10.1 6.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain MGC-24 PF05283.11 EEQ33981.1 - 1.3 9.5 18.3 12 6.4 18.3 2.1 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pex14_N PF04695.13 EEQ33981.1 - 1.4 9.6 8.6 0.048 14.3 2.7 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM199X PF15814.5 EEQ33981.1 - 4.2 6.3 12.9 6.5 5.7 12.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X Mucin PF01456.17 EEQ33981.1 - 9.7 6.2 23.5 16 5.5 23.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RR_TM4-6 PF06459.12 EEQ33984.1 - 0.4 10.5 8.4 0.46 10.3 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ORC6 PF05460.13 EEQ33985.1 - 0.024 13.9 5.3 0.029 13.7 5.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CENP-U PF13097.6 EEQ33985.1 - 0.28 11.1 4.2 0.39 10.7 4.2 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Abp2 PF09441.10 EEQ33986.1 - 8.3e-84 279.9 0.1 1.3e-83 279.3 0.1 1.3 1 0 0 1 1 1 1 ARS binding protein 2 LRR_4 PF12799.7 EEQ33987.1 - 1.1 9.8 4.1 81 3.8 0.1 4.2 4 1 3 7 7 7 0 Leucine Rich repeats (2 copies) WW PF00397.26 EEQ33988.1 - 3.2e-10 39.9 2.5 7.3e-10 38.8 2.5 1.7 1 0 0 1 1 1 1 WW domain Brix PF04427.18 EEQ33989.1 - 1.9e-32 113.0 0.0 2.5e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.12 EEQ33989.1 - 0.53 8.4 9.4 0.95 7.6 9.4 1.4 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EEQ33989.1 - 2.8 6.4 4.5 4.1 5.8 4.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 EEQ33989.1 - 7.3 5.8 18.0 2.7 7.2 12.8 2.1 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 EEQ33989.1 - 9.8 4.3 9.7 0.35 9.1 4.1 1.4 2 0 0 2 2 2 0 CDC45-like protein F-box-like PF12937.7 EEQ33990.1 - 1e-07 31.7 0.2 7e-07 29.0 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EEQ33990.1 - 0.0016 18.3 0.2 0.0052 16.6 0.2 1.9 1 0 0 1 1 1 1 F-box domain Ribosomal_L14e PF01929.17 EEQ33990.1 - 0.075 13.5 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L14 DUF3630 PF12305.8 EEQ33990.1 - 0.14 12.3 0.5 0.9 9.7 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3630) Ras PF00071.22 EEQ33991.1 - 4.8e-62 208.3 0.2 5.8e-62 208.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ33991.1 - 2e-34 118.4 0.2 2.9e-34 117.9 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ33991.1 - 9.2e-13 48.0 0.1 1.2e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEQ33991.1 - 2.1e-07 31.0 0.1 3.3e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ33991.1 - 0.00019 21.4 1.2 0.012 15.5 0.1 2.2 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EEQ33991.1 - 0.00026 20.6 0.2 0.0015 18.1 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EEQ33991.1 - 0.0011 19.2 0.1 0.0074 16.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 EEQ33991.1 - 0.0025 17.2 0.1 0.004 16.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EEQ33991.1 - 0.0041 16.6 0.0 0.0053 16.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EEQ33991.1 - 0.0058 17.0 0.1 0.0093 16.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EEQ33991.1 - 0.0077 16.3 0.1 0.026 14.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EEQ33991.1 - 0.0096 16.4 0.1 0.013 16.1 0.1 1.5 1 1 0 1 1 1 1 ABC transporter TniB PF05621.11 EEQ33991.1 - 0.031 13.7 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SpoIIID PF12116.8 EEQ33991.1 - 0.043 13.9 0.1 0.88 9.7 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D MCM PF00493.23 EEQ33991.1 - 0.05 12.7 0.0 0.12 11.5 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 EEQ33991.1 - 0.063 13.0 0.1 0.15 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEQ33991.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF790 PF05626.11 EEQ33991.1 - 0.096 11.4 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) AAA_21 PF13304.6 EEQ33991.1 - 0.1 12.4 0.9 0.22 11.3 0.5 1.6 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 EEQ33992.1 - 1.3e-08 34.7 0.2 3.1e-08 33.4 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EEQ33992.1 - 0.0047 17.1 0.0 0.0095 16.1 0.0 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 AAA_2 PF07724.14 EEQ33993.1 - 4.5e-38 131.1 0.0 3.5e-37 128.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EEQ33993.1 - 1.1e-14 54.9 0.0 2.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EEQ33993.1 - 2.8e-09 36.9 0.3 9e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EEQ33993.1 - 1.6e-06 28.1 0.0 3.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EEQ33993.1 - 0.00015 21.2 0.1 0.0076 15.7 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EEQ33993.1 - 0.00026 20.8 0.0 0.094 12.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 EEQ33993.1 - 0.0024 17.0 0.5 0.0064 15.6 0.1 1.8 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 EEQ33993.1 - 0.0029 18.0 0.1 0.014 15.8 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EEQ33993.1 - 0.0037 17.0 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEQ33993.1 - 0.0037 17.5 0.3 0.032 14.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EEQ33993.1 - 0.005 16.6 0.2 0.075 12.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EEQ33993.1 - 0.0052 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 EEQ33993.1 - 0.042 13.4 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EEQ33993.1 - 0.054 14.0 0.2 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EEQ33993.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EEQ33993.1 - 0.064 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.11 EEQ33993.1 - 0.094 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EEQ33993.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EEQ33993.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FAD_binding_4 PF01565.23 EEQ33996.1 - 3.3e-19 69.0 0.4 5.5e-19 68.3 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EEQ33996.1 - 9.1e-11 41.7 0.1 2.2e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like ATP-synt_ab PF00006.25 EEQ33997.1 - 5.7e-62 209.1 0.0 9.2e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EEQ33997.1 - 9.3e-22 77.3 2.6 2.8e-21 75.8 2.2 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 EEQ33997.1 - 0.0074 16.2 0.5 0.031 14.2 0.0 2.1 3 0 0 3 3 3 1 RsgA GTPase AAA PF00004.29 EEQ33997.1 - 0.0091 16.4 0.0 0.59 10.6 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EEQ33997.1 - 0.019 14.1 0.3 0.097 11.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EEQ33997.1 - 0.026 14.4 0.0 0.079 12.9 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EEQ33997.1 - 0.035 14.4 1.0 0.48 10.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EEQ33997.1 - 0.047 13.0 0.2 0.085 12.2 0.2 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EEQ33997.1 - 0.047 13.6 0.2 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain T3SS_ATPase_C PF18269.1 EEQ33997.1 - 0.057 13.3 0.8 0.28 11.1 0.8 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 EEQ33997.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EEQ33997.1 - 0.094 13.1 0.1 0.36 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Alpha-amylase_C PF02806.18 EEQ33998.1 - 5.8e-26 90.8 0.0 1.6e-25 89.4 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EEQ33998.1 - 7.7e-19 67.8 0.0 2.2e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EEQ33998.1 - 4.9e-17 62.5 0.0 1.6e-11 44.4 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain COX4 PF02936.14 EEQ33999.1 - 1e-43 148.6 0.3 1.4e-43 148.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.11 EEQ33999.1 - 0.17 12.2 1.1 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Cofilin_ADF PF00241.20 EEQ34000.1 - 5.7e-34 116.5 0.0 6.8e-34 116.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoVR PF04293.13 EEQ34000.1 - 0.1 11.2 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 SpoVR like protein Cpn60_TCP1 PF00118.24 EEQ34001.1 - 1.5e-85 287.7 10.0 2.2e-85 287.1 10.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CHASE6_C PF17150.4 EEQ34001.1 - 0.045 14.4 0.0 22 5.8 0.0 2.7 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain Myb_DNA-binding PF00249.31 EEQ34002.1 - 0.00043 20.4 0.0 0.00083 19.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ATP-synt_Eps PF04627.13 EEQ34003.1 - 2.5e-22 78.6 0.9 3.4e-22 78.1 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.13 EEQ34004.1 - 1.2e-60 203.8 0.0 3.5e-60 202.3 0.0 1.8 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase SpecificRecomb PF10136.9 EEQ34004.1 - 0.00047 18.6 0.3 0.00068 18.1 0.3 1.1 1 0 0 1 1 1 1 Site-specific recombinase ORC5_C PF14630.6 EEQ34005.1 - 8.1e-79 265.1 0.0 1.1e-78 264.7 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EEQ34005.1 - 4.7e-24 85.7 0.0 8e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ34005.1 - 0.00018 21.8 0.0 0.00053 20.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EEQ34005.1 - 0.0006 19.8 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 EEQ34005.1 - 0.0013 18.2 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.6 EEQ34005.1 - 0.0014 19.2 0.0 0.0022 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ34005.1 - 0.0075 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEQ34005.1 - 0.015 15.1 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EEQ34005.1 - 0.016 14.5 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 EEQ34005.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EEQ34005.1 - 0.019 15.4 0.0 0.11 12.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EEQ34005.1 - 0.021 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_27 PF13514.6 EEQ34005.1 - 0.04 13.5 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EEQ34005.1 - 0.044 14.3 0.0 0.078 13.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EEQ34005.1 - 0.058 14.0 0.0 0.092 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEQ34005.1 - 0.072 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EEQ34005.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEQ34005.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EEQ34005.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 EEQ34005.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EEQ34005.1 - 0.19 11.6 0.0 0.46 10.4 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 EEQ34005.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EEQ34005.1 - 0.21 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 EEQ34005.1 - 0.26 10.4 0.0 0.46 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 EEQ34005.1 - 0.26 11.2 0.0 0.41 10.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain PUF PF00806.19 EEQ34006.1 - 2.6e-55 181.1 9.6 1.8e-07 30.5 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat RNA_pol_Rpb2_6 PF00562.28 EEQ34008.1 - 3.3e-124 414.9 0.0 5.5e-124 414.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EEQ34008.1 - 4.8e-56 189.5 0.4 7.1e-56 188.9 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EEQ34008.1 - 1.1e-30 105.9 0.3 2.6e-30 104.7 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EEQ34008.1 - 2.2e-29 102.5 1.7 5.8e-29 101.1 1.5 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EEQ34008.1 - 3.2e-25 88.2 0.5 9.1e-25 86.7 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EEQ34008.1 - 3.2e-18 65.7 0.0 7.7e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EEQ34008.1 - 2.1e-11 44.2 0.5 7e-11 42.5 0.5 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L22e PF01776.17 EEQ34008.1 - 0.052 13.9 0.7 0.69 10.3 0.0 2.5 2 0 0 2 2 2 0 Ribosomal L22e protein family DUF3632 PF12311.8 EEQ34009.1 - 3.7e-36 125.2 3.0 5.9e-36 124.5 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Glycos_transf_1 PF00534.20 EEQ34013.1 - 5e-19 68.5 0.0 9.5e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEQ34013.1 - 2.1e-13 50.8 0.0 3.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EEQ34013.1 - 0.0017 18.7 0.0 0.0043 17.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 CUTL PF16557.5 EEQ34013.1 - 0.013 15.6 0.6 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 CUT1-like DNA-binding domain of SATB E1-E2_ATPase PF00122.20 EEQ34014.1 - 1.1e-36 126.1 4.2 1.1e-36 126.1 4.2 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EEQ34014.1 - 1.7e-17 64.4 0.0 4.8e-17 62.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEQ34014.1 - 1.4e-11 43.9 0.0 3.2e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EEQ34014.1 - 0.0013 18.8 0.5 0.003 17.6 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEQ34014.1 - 0.0048 16.7 0.1 0.0048 16.7 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 EEQ34014.1 - 0.038 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) O-antigen_lig PF13425.6 EEQ34014.1 - 0.12 11.1 5.5 0.33 9.7 5.5 1.7 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RRM_1 PF00076.22 EEQ34017.1 - 1.3e-06 28.2 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EEQ34017.1 - 9.9e-05 23.1 0.0 0.00021 22.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. TFIIA PF03153.13 EEQ34017.1 - 6.3 6.7 22.0 9 6.2 22.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Citrate_synt PF00285.21 EEQ34018.1 - 1.2e-100 337.1 0.0 1.6e-100 336.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EEQ34018.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 EEQ34020.1 - 1.2e-25 89.3 3.9 3.3e-11 43.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M16 PF00675.20 EEQ34021.1 - 2.5e-18 66.5 0.0 4.7e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEQ34021.1 - 9.7e-13 48.5 0.0 1.8e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 EEQ34022.1 - 4.6e-39 134.7 0.0 8.7e-35 120.7 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EEQ34022.1 - 1.7e-16 60.1 3.8 1.3e-09 38.0 0.2 4.0 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EEQ34022.1 - 1.1e-06 28.4 0.1 8.4e-06 25.6 0.1 2.3 2 0 0 2 2 2 1 TFIIE alpha subunit CENP-B_dimeris PF09026.10 EEQ34022.1 - 0.16 12.3 0.2 0.16 12.3 0.2 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EEQ34022.1 - 1.4 9.3 5.6 6.4 7.2 0.9 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GCIP PF13324.6 EEQ34022.1 - 5.3 6.6 7.1 11 5.5 0.8 2.9 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting Sec8_exocyst PF04048.14 EEQ34023.1 - 6e-23 81.3 6.0 1.8e-17 63.6 0.0 3.4 4 0 0 4 4 4 2 Sec8 exocyst complex component specific domain Tannase PF07519.11 EEQ34025.1 - 2.8e-96 323.3 0.0 3.4e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EEQ34025.1 - 0.002 17.7 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EEQ34025.1 - 0.0039 16.5 0.0 0.055 12.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Aldo_ket_red PF00248.21 EEQ34026.1 - 1.4e-37 129.5 0.0 1e-27 97.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Rit1_C PF17184.4 EEQ34027.1 - 2.5e-77 260.0 0.0 2.4e-45 155.1 0.0 2.2 1 1 1 2 2 2 2 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EEQ34027.1 - 4.8e-36 123.4 0.0 1e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain HAD_2 PF13419.6 EEQ34028.1 - 3.8e-19 69.5 0.0 5.4e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ34028.1 - 7.7e-07 29.6 0.1 8.2e-06 26.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EEQ34028.1 - 3.1e-06 27.0 0.0 7.6e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 EEQ34028.1 - 0.00034 20.6 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NUDIX PF00293.28 EEQ34029.1 - 5.7e-16 58.8 0.0 1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Gln-synt_N_2 PF16952.5 EEQ34029.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain Cnd1_N PF12922.7 EEQ34029.1 - 0.097 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term NUDIX PF00293.28 EEQ34030.1 - 9.2e-10 38.7 0.0 1.6e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Bacteroid_pep PF14406.6 EEQ34031.1 - 0.58 10.6 2.6 1.6 9.2 2.6 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes EST1_DNA_bind PF10373.9 EEQ34032.1 - 6.4e-11 42.2 0.3 1.5e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain TFIIB PF00382.19 EEQ34033.1 - 0.0051 16.8 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Autophagy_N PF03986.13 EEQ34034.1 - 9.8e-45 151.9 0.0 9.8e-45 151.9 0.0 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 EEQ34034.1 - 1.3e-15 56.5 0.5 2.4e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 EEQ34034.1 - 1.4e-13 51.1 0.1 2.5e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Nop25 PF09805.9 EEQ34034.1 - 0.19 12.2 6.7 1.3 9.5 2.2 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Fez1 PF06818.15 EEQ34035.1 - 0.027 14.9 0.1 0.044 14.2 0.1 1.2 1 0 0 1 1 1 0 Fez1 Dicty_CAR PF05462.11 EEQ34036.1 - 0.00032 20.0 3.4 0.00032 20.0 3.4 3.0 2 1 0 3 3 3 2 Slime mold cyclic AMP receptor Git3 PF11710.8 EEQ34036.1 - 0.006 16.4 4.1 0.006 16.4 4.1 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EEQ34036.1 - 0.018 15.1 0.5 0.065 13.3 0.5 2.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term Glycos_transf_2 PF00535.26 EEQ34037.1 - 3.1e-23 82.4 0.1 6.3e-21 74.9 0.1 3.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EEQ34037.1 - 8.8e-07 29.0 0.1 0.042 13.7 0.1 3.0 1 1 2 3 3 3 2 Glycosyltransferase like family 2 HOOK PF05622.12 EEQ34038.1 - 0.0042 15.3 5.5 0.39 8.8 4.2 2.3 2 0 0 2 2 2 2 HOOK protein SKA1 PF07160.12 EEQ34038.1 - 0.013 15.3 0.4 0.033 14.1 0.4 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 T3SSipB PF16535.5 EEQ34038.1 - 0.017 15.6 4.6 0.033 14.7 4.6 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB Sec8_exocyst PF04048.14 EEQ34038.1 - 0.081 12.8 0.7 0.18 11.7 0.7 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain ASXH PF13919.6 EEQ34038.1 - 0.082 12.9 1.5 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Asx homology domain Pox_A_type_inc PF04508.12 EEQ34038.1 - 0.082 12.8 3.9 1.1 9.2 0.6 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Phage_GPO PF05929.11 EEQ34038.1 - 0.18 11.4 5.8 0.39 10.3 5.0 1.9 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 EEQ34038.1 - 0.21 11.8 1.1 1.9 8.7 0.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cauli_AT PF03233.13 EEQ34038.1 - 0.32 10.9 2.7 0.43 10.5 1.3 1.9 2 0 0 2 2 2 0 Aphid transmission protein DUF16 PF01519.16 EEQ34038.1 - 0.35 11.4 2.5 0.85 10.1 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 GvpL_GvpF PF06386.11 EEQ34038.1 - 0.5 10.3 4.8 1.1 9.2 2.7 2.3 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF4407 PF14362.6 EEQ34038.1 - 0.68 9.2 4.7 1.3 8.4 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 EEQ34038.1 - 1.2 10.0 12.1 16 6.5 5.6 3.3 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF2570 PF10828.8 EEQ34038.1 - 3 7.7 9.7 0.16 11.8 3.4 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Cnn_1N PF07989.11 EEQ34038.1 - 3.6 7.8 7.6 3.7 7.8 2.7 2.7 3 0 0 3 3 2 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 EEQ34038.1 - 4.2 6.2 11.7 1.6 7.6 9.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Swi5 PF07061.11 EEQ34039.1 - 2.5e-29 101.2 0.4 3.5e-29 100.7 0.4 1.2 1 0 0 1 1 1 1 Swi5 Prefoldin_2 PF01920.20 EEQ34039.1 - 0.025 14.5 0.9 0.048 13.6 0.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF812 PF05667.11 EEQ34039.1 - 0.028 13.3 0.3 0.032 13.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tropomyosin_1 PF12718.7 EEQ34039.1 - 0.033 14.4 0.6 0.039 14.1 0.6 1.1 1 0 0 1 1 1 0 Tropomyosin like LemA PF04011.12 EEQ34039.1 - 0.064 13.1 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 LemA family DUF1366 PF07104.11 EEQ34039.1 - 0.072 12.8 0.4 0.099 12.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) XhlA PF10779.9 EEQ34039.1 - 0.077 13.2 1.4 0.14 12.4 1.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA DivIC PF04977.15 EEQ34039.1 - 0.27 11.0 1.8 3.5 7.5 1.8 2.0 1 1 1 2 2 2 0 Septum formation initiator Ytp1 PF10355.9 EEQ34040.1 - 1.9e-69 233.9 17.7 1.9e-69 233.9 17.7 2.2 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EEQ34040.1 - 1.8e-31 108.0 4.3 1.8e-31 108.0 4.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) ExoD PF06055.12 EEQ34040.1 - 0.027 13.8 0.1 0.027 13.8 0.1 2.8 3 0 0 3 3 3 0 Exopolysaccharide synthesis, ExoD DUF973 PF06157.11 EEQ34040.1 - 0.11 11.5 6.4 0.23 10.5 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3180 PF11377.8 EEQ34040.1 - 0.14 12.3 7.7 0.69 10.1 4.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) ThiF PF00899.21 EEQ34041.1 - 3.5e-34 118.3 0.0 4.5e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 ThiF family MFS_1 PF07690.16 EEQ34043.1 - 1.2e-34 119.9 24.4 1.6e-34 119.4 24.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.22 EEQ34043.1 - 0.91 8.5 35.2 0.49 9.4 17.2 3.1 2 1 1 3 3 3 0 Acyltransferase family Na_H_Exchanger PF00999.21 EEQ34044.1 - 8.5e-60 202.5 44.5 1.2e-59 202.0 44.5 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peroxin-3 PF04882.12 EEQ34045.1 - 4.4e-165 550.2 0.1 5.2e-165 550.0 0.1 1.0 1 0 0 1 1 1 1 Peroxin-3 ATG101 PF07855.12 EEQ34046.1 - 1.9e-54 183.8 0.1 2.2e-54 183.6 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 DUF2922 PF11148.8 EEQ34046.1 - 0.00017 21.2 0.1 0.00067 19.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2922) TB2_DP1_HVA22 PF03134.19 EEQ34047.1 - 8.5e-24 83.3 8.0 1.6e-23 82.4 8.0 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.15 EEQ34048.1 - 5.9e-27 94.1 0.1 1.4e-26 92.9 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain PIG-X PF08320.12 EEQ34049.1 - 1.3e-68 231.1 0.1 1.8e-68 230.6 0.1 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 DnaJ_C PF01556.18 EEQ34050.1 - 9.6e-36 123.1 0.4 1.3e-35 122.7 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEQ34050.1 - 1.1e-27 95.9 2.8 2e-27 95.1 2.8 1.5 1 0 0 1 1 1 1 DnaJ domain MMR_HSR1_Xtn PF16897.5 EEQ34051.1 - 1.2e-34 118.6 1.3 6.7e-34 116.1 0.4 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EEQ34051.1 - 1.9e-20 73.0 0.0 4.3e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EEQ34051.1 - 1.1e-19 70.2 0.4 2.2e-19 69.2 0.1 1.7 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 EEQ34051.1 - 1.2e-12 47.6 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EEQ34051.1 - 5.1e-05 23.4 0.3 0.045 13.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 EEQ34051.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 EEQ34051.1 - 0.088 11.8 0.1 0.17 10.8 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EEQ34051.1 - 0.1 12.8 0.1 3.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Torus PF16131.5 EEQ34052.1 - 9.2e-46 155.0 1.7 4.6e-45 152.8 0.0 2.6 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 EEQ34052.1 - 1.6e-08 34.2 0.0 4.4e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EEQ34052.1 - 0.00026 20.9 1.0 0.00047 20.1 1.0 1.5 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 EEQ34052.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EEQ34052.1 - 0.026 14.4 1.7 0.047 13.6 1.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EEQ34052.1 - 1.1 9.1 3.8 1.9 8.4 3.8 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger HGTP_anticodon2 PF12745.7 EEQ34053.1 - 2.4e-84 282.9 0.1 2.4e-84 282.9 0.1 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EEQ34053.1 - 1.4e-67 227.9 0.0 8.5e-36 123.7 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34053.1 - 2e-34 119.1 0.0 4.1e-18 65.6 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EEQ34053.1 - 7e-19 68.2 1.8 1.4e-18 67.2 0.4 2.3 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 EEQ34053.1 - 2e-11 43.7 0.6 9.8e-11 41.5 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 EEQ34053.1 - 0.0051 16.8 0.1 0.0051 16.8 0.1 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 EEQ34053.1 - 0.081 12.5 0.0 0.82 9.2 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EEQ34053.1 - 0.25 10.1 2.1 0.34 9.6 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Cut12 PF11500.8 EEQ34054.1 - 1.4e-46 158.0 15.6 1.4e-46 158.0 15.6 4.7 4 1 3 7 7 7 1 Spindle pole body formation-associated protein DUF2730 PF10805.8 EEQ34054.1 - 1 9.5 7.9 0.18 11.9 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Glutaredoxin2_C PF04399.13 EEQ34054.1 - 1.3 8.9 6.2 3.5 7.5 0.5 2.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain HGD-D PF06050.13 EEQ34054.1 - 2.1 8.0 4.9 0.52 10.0 1.4 1.6 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF89 PF01937.19 EEQ34055.1 - 8.6e-135 449.2 0.0 9.8e-135 449.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CENP-F_leu_zip PF10473.9 EEQ34055.1 - 0.062 13.3 0.3 0.15 12.1 0.3 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PPP5 PF08321.12 EEQ34056.1 - 2.1e-33 114.5 0.1 4.8e-33 113.3 0.1 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 EEQ34056.1 - 1.2e-30 107.6 0.0 1.7e-30 107.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EEQ34056.1 - 1.7e-10 40.2 1.5 0.00093 18.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ34056.1 - 4.1e-08 32.8 2.4 0.031 14.4 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ34056.1 - 6.8e-08 32.1 0.6 0.0073 16.0 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 EEQ34056.1 - 1.1e-06 28.7 0.1 0.0019 18.3 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ34056.1 - 0.0006 20.4 3.0 0.35 11.5 0.0 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ34056.1 - 0.0018 18.5 0.5 3.2 8.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ34056.1 - 0.0038 17.7 0.2 0.33 11.5 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ34056.1 - 0.053 13.8 0.1 0.16 12.3 0.1 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ34056.1 - 0.056 14.1 0.4 12 6.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ34056.1 - 0.063 14.1 1.3 19 6.4 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ34056.1 - 0.17 12.2 0.3 2 8.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Spt4 PF06093.13 EEQ34057.1 - 1.3e-32 111.7 0.2 1.6e-32 111.4 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 EEQ34057.1 - 0.058 13.4 0.2 0.1 12.6 0.2 1.5 1 1 0 1 1 1 0 Coronavirus gene 5 protein Aminotran_3 PF00202.21 EEQ34058.1 - 4.4e-125 417.5 0.0 5.1e-125 417.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EEQ34058.1 - 0.048 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II NAD_binding_4 PF07993.12 EEQ34059.1 - 6.2e-30 104.2 0.0 4.2e-28 98.2 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 EEQ34059.1 - 8e-27 93.9 0.0 1.6e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EEQ34059.1 - 1.6e-05 25.1 0.0 4.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EEQ34059.1 - 0.00022 20.7 0.0 0.00069 19.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.13 EEQ34060.1 - 1.7e-34 119.5 0.0 2.9e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ34060.1 - 0.00013 21.3 0.0 0.0041 16.4 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EEQ34060.1 - 0.0033 16.9 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EEQ34060.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF5131 PF07505.11 EEQ34060.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) GMC_oxred_C PF05199.13 EEQ34061.1 - 2.4e-16 60.6 0.0 2.8e-15 57.1 0.0 2.2 1 1 1 2 2 2 1 GMC oxidoreductase Zn_clus PF00172.18 EEQ34061.1 - 1.7e-07 31.2 10.7 4e-07 30.0 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ34061.1 - 0.0062 15.6 0.4 0.012 14.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bestrophin PF01062.21 EEQ34062.1 - 4e-35 121.6 0.0 7.2e-35 120.8 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel AOX PF01786.17 EEQ34065.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Alternative oxidase GSH_synth_ATP PF03917.17 EEQ34066.1 - 2.8e-129 431.1 0.0 3.2e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EEQ34066.1 - 3.9e-27 94.7 0.0 6.2e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 EEQ34067.1 - 2.7e-47 161.2 0.2 5.6e-47 160.1 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ34067.1 - 1.1e-16 61.2 0.0 2.7e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ34067.1 - 2.1e-08 34.3 0.1 1.2e-06 28.6 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EEQ34067.1 - 1.4e-05 24.4 0.0 3.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EEQ34067.1 - 5.5e-05 23.0 0.1 0.21 11.2 0.0 3.6 4 0 0 4 4 4 2 SWI2/SNF2 ATPase SAM_1 PF00536.30 EEQ34067.1 - 0.0049 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EEQ34067.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SNF2_N PF00176.23 EEQ34068.1 - 1e-68 231.7 0.0 1.5e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EEQ34068.1 - 1.3e-15 57.1 0.0 3.3e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EEQ34068.1 - 1.9e-14 53.9 0.0 7.2e-14 52.1 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EEQ34068.1 - 2.4e-10 40.1 7.2 6.7e-10 38.6 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ34068.1 - 9e-09 35.5 7.3 9e-09 35.5 7.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EEQ34068.1 - 4.4e-08 32.9 8.7 4.4e-08 32.9 8.7 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ34068.1 - 1e-06 28.5 8.6 2.3e-06 27.4 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ34068.1 - 2.9e-06 27.5 3.9 7.4e-06 26.2 3.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEQ34068.1 - 1.2e-05 25.2 8.4 1.2e-05 25.2 8.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ34068.1 - 2e-05 24.4 5.5 4.7e-05 23.3 5.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EEQ34068.1 - 3e-05 23.7 2.9 3e-05 23.7 2.9 2.7 3 0 0 3 3 3 1 RING-like zinc finger Prok-RING_4 PF14447.6 EEQ34068.1 - 0.00019 21.3 9.3 0.00046 20.0 9.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EEQ34068.1 - 0.00036 20.6 9.4 0.00069 19.7 9.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.29 EEQ34068.1 - 0.00073 19.4 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-Nse PF11789.8 EEQ34068.1 - 0.0013 18.6 7.6 0.0053 16.5 5.0 2.8 3 0 0 3 3 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EEQ34068.1 - 0.0089 16.2 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 U-box domain SCAN PF02023.17 EEQ34068.1 - 0.17 11.7 1.3 0.44 10.4 0.4 2.1 2 0 0 2 2 2 0 SCAN domain zf-ANAPC11 PF12861.7 EEQ34068.1 - 0.22 11.6 1.8 0.7 10.0 1.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SIT PF15330.6 EEQ34068.1 - 0.58 10.6 3.7 0.37 11.2 0.8 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT zf-RING_4 PF14570.6 EEQ34068.1 - 2 8.2 4.1 4.3 7.2 4.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MBOAT_2 PF13813.6 EEQ34069.1 - 6.7e-20 71.2 2.5 1.7e-19 69.9 2.5 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RIX1 PF08167.12 EEQ34070.1 - 5.5e-62 208.9 3.4 1.6e-61 207.4 3.4 1.8 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Terminase_6C PF17289.2 EEQ34070.1 - 0.04 14.0 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 Terminase RNaseH-like domain UPF0149 PF03695.13 EEQ34070.1 - 0.15 12.4 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) TPR_14 PF13428.6 EEQ34071.1 - 4.7e-10 39.4 15.4 0.015 16.1 0.0 7.8 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ34071.1 - 2.9e-09 36.3 0.7 0.2 11.8 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ34071.1 - 5.8e-08 33.1 7.3 0.0098 16.4 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ34071.1 - 3e-07 30.1 0.1 0.067 13.4 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ34071.1 - 9.9e-06 26.1 5.9 0.23 12.1 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ34071.1 - 1.3e-05 25.2 0.2 4.5 7.9 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ34071.1 - 1.9e-05 24.3 1.3 0.013 15.3 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ34071.1 - 0.023 15.0 4.3 5 7.5 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 EEQ34071.1 - 0.19 12.1 1.1 11 6.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ34071.1 - 0.2 12.4 3.8 8.5 7.3 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NDUFA12 PF05071.16 EEQ34072.1 - 1.9e-32 112.0 3.4 2.3e-32 111.7 3.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 EEQ34073.1 - 9.3e-16 57.9 0.0 8.8e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EEQ34073.1 - 2.6e-10 40.0 0.2 0.00012 22.1 0.0 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif LTV PF04180.14 EEQ34074.1 - 3.3e-117 392.5 14.7 3.7e-117 392.3 14.7 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.23 EEQ34075.1 - 2.1e-16 60.0 0.3 2.4e-14 53.4 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ34075.1 - 6.2e-07 29.1 0.3 1.7e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEQ34075.1 - 8e-05 22.6 0.1 0.028 14.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EEQ34075.1 - 0.0017 18.4 0.9 0.28 11.2 0.3 3.1 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.16 EEQ34075.1 - 0.0028 17.0 0.1 0.0054 16.1 0.1 1.4 1 0 0 1 1 1 1 AIG1 family zf-C2H2_11 PF16622.5 EEQ34076.1 - 0.0056 16.4 0.1 0.02 14.7 0.1 2.0 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 EEQ34076.1 - 0.0075 16.7 10.2 0.066 13.7 0.4 3.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ34076.1 - 0.011 16.5 8.4 0.088 13.7 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ34076.1 - 0.12 12.7 0.5 0.6 10.5 0.0 2.4 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding Fungal_trans PF04082.18 EEQ34077.1 - 5.7e-16 58.4 0.8 2.8e-15 56.1 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EEQ34077.1 - 5.4e-11 42.3 9.8 6.2e-05 23.2 3.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ34077.1 - 3.7e-08 33.5 9.3 0.0012 19.5 2.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEQ34077.1 - 3.1e-07 30.5 3.7 3.1e-07 30.5 3.7 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EEQ34077.1 - 0.0003 21.0 1.1 0.098 13.0 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ34077.1 - 0.049 14.0 2.3 0.86 10.1 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 EEQ34077.1 - 1.5 8.9 4.0 5.3 7.1 1.4 2.5 1 1 1 2 2 2 0 BED zinc finger Pkinase PF00069.25 EEQ34078.1 - 2.2e-69 233.8 0.0 1.1e-68 231.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34078.1 - 1.9e-47 161.7 0.0 4.5e-47 160.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EEQ34078.1 - 4.2e-28 97.6 0.0 8e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 EEQ34078.1 - 7.1e-16 58.4 0.1 1.6e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EEQ34078.1 - 9.8e-14 51.2 0.0 2.2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 EEQ34078.1 - 5e-08 32.6 0.0 0.00026 20.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 EEQ34078.1 - 8.1e-05 23.2 0.0 0.00016 22.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 EEQ34078.1 - 0.0025 16.7 0.8 0.0046 15.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EEQ34078.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_4 PF18017.1 EEQ34078.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pneumo_M2 PF07380.11 EEQ34078.1 - 0.1 12.9 0.1 0.61 10.4 0.0 2.3 3 0 0 3 3 3 0 Pneumovirus M2 protein Seadorna_VP7 PF07387.11 EEQ34078.1 - 0.18 10.9 0.1 0.88 8.6 0.0 2.2 3 0 0 3 3 3 0 Seadornavirus VP7 Ribosomal_L5_C PF00673.21 EEQ34079.1 - 2.1e-28 98.4 0.0 3.5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EEQ34079.1 - 5.9e-05 23.3 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 CoA_binding PF02629.19 EEQ34080.1 - 5.6e-27 94.3 4.2 7.3e-27 93.9 2.0 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EEQ34080.1 - 2.5e-22 79.3 0.2 4.6e-22 78.5 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EEQ34080.1 - 1.9e-08 34.2 0.1 4.4e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EEQ34080.1 - 1.4e-05 25.5 0.1 3.1e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Radical_SAM_C PF16199.5 EEQ34081.1 - 1.8e-32 111.2 0.1 4.6e-32 109.9 0.0 1.7 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EEQ34081.1 - 4.2e-19 69.5 0.1 3e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EEQ34081.1 - 2.7e-09 37.3 0.0 5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ34081.1 - 7.1e-06 26.0 0.2 7.4e-05 22.7 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ34081.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4064 PF13273.6 EEQ34082.1 - 0.0017 18.6 0.6 0.0022 18.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) LMBR1 PF04791.16 EEQ34082.1 - 0.13 11.1 3.0 0.15 10.9 3.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Insulin_TMD PF17870.1 EEQ34082.1 - 0.23 11.6 1.7 13 5.9 1.0 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF2207 PF09972.9 EEQ34082.1 - 0.54 9.0 1.5 0.61 8.8 1.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pox_EPC_I2-L1 PF12575.8 EEQ34082.1 - 1.1 9.6 3.6 5.1 7.4 1.4 2.1 1 1 1 2 2 2 0 Poxvirus entry protein complex L1 and I2 His_biosynth PF00977.21 EEQ34083.1 - 3.1e-31 108.6 0.0 3.7e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EEQ34083.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.6 EEQ34084.1 - 1.4e-11 44.8 5.3 1.4e-11 44.8 5.3 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4602) S1FA PF04689.13 EEQ34084.1 - 0.083 13.0 0.3 0.24 11.6 0.3 1.7 1 0 0 1 1 1 0 DNA binding protein S1FA STE PF02200.16 EEQ34085.1 - 1.1e-46 157.7 0.0 2.4e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EEQ34085.1 - 0.0021 18.4 3.4 0.0065 16.9 3.4 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ34085.1 - 0.087 13.7 2.3 0.3 12.0 2.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger MFS_2 PF13347.6 EEQ34086.1 - 1.5e-08 33.7 5.7 1.5e-08 33.7 5.7 2.0 2 1 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 EEQ34086.1 - 0.00025 20.2 0.8 0.00046 19.3 0.8 1.3 1 0 0 1 1 1 1 PUCC protein MFS_1 PF07690.16 EEQ34086.1 - 0.00087 18.3 37.1 0.053 12.4 31.5 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Na_H_Exchanger PF00999.21 EEQ34088.1 - 3.5e-72 243.3 35.5 4.3e-72 243.0 35.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Kelch_6 PF13964.6 EEQ34088.1 - 0.15 12.4 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 Kelch motif SNF2_N PF00176.23 EEQ34089.1 - 1e-64 218.5 2.0 1e-64 218.5 2.0 2.0 2 1 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 EEQ34089.1 - 1.4e-47 161.4 20.6 1.4e-47 161.4 20.6 4.8 4 1 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 EEQ34089.1 - 4.9e-19 68.7 0.0 1.3e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ34089.1 - 2.1e-06 27.9 3.6 3.3e-06 27.2 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEQ34089.1 - 0.00019 21.2 0.0 0.00052 19.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase YgaB PF14182.6 EEQ34089.1 - 0.0021 18.4 5.0 0.0099 16.3 2.0 3.0 2 0 0 2 2 2 1 YgaB-like protein HDA2-3 PF11496.8 EEQ34089.1 - 0.011 15.0 2.6 0.057 12.6 0.0 3.0 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 baeRF_family12 PF18856.1 EEQ34089.1 - 0.015 15.9 0.2 0.015 15.9 0.2 4.7 5 1 0 5 5 5 0 Bacterial archaeo-eukaryotic release factor family 12 PET PF06297.14 EEQ34089.1 - 0.69 10.3 7.0 0.26 11.6 3.0 2.5 2 0 0 2 2 2 0 PET Domain Pep3_Vps18 PF05131.14 EEQ34091.1 - 3.7e-46 156.6 0.0 8.8e-46 155.4 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EEQ34091.1 - 1.4e-09 38.0 1.6 1.6e-05 24.8 0.0 3.1 3 0 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EEQ34091.1 - 0.00018 21.1 0.2 0.00038 20.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EEQ34091.1 - 0.0009 19.0 1.0 0.0025 17.6 1.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ34091.1 - 0.001 19.0 0.7 0.0023 17.8 0.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.9 EEQ34091.1 - 0.0019 18.4 0.6 0.0081 16.4 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_11 PF17123.5 EEQ34091.1 - 0.002 17.9 4.3 0.002 17.9 4.3 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EEQ34091.1 - 0.005 17.1 0.8 0.013 15.8 0.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EEQ34091.1 - 0.036 14.1 0.9 0.092 12.8 0.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.9 EEQ34091.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 EEQ34091.1 - 0.058 13.7 0.3 0.29 11.4 0.6 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EEQ34091.1 - 0.19 11.6 2.3 0.13 12.1 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 EEQ34093.1 - 5.4e-46 157.1 0.0 8e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34093.1 - 1.2e-28 100.1 0.0 1.7e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ34093.1 - 8.5e-09 35.1 0.0 2.5e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EEQ34093.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.13 EEQ34094.1 - 8.9e-31 106.6 0.0 1.5e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal KRAP_IP3R_bind PF14722.6 EEQ34094.1 - 0.012 15.3 0.1 0.037 13.8 0.1 1.8 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain DUF3391 PF11871.8 EEQ34094.1 - 0.1 13.2 4.1 0.39 11.3 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Mito_fiss_reg PF05308.11 EEQ34094.1 - 0.79 9.8 11.5 1.8 8.6 2.1 2.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Spo12 PF05032.12 EEQ34095.1 - 8.5e-15 54.4 0.8 1.8e-14 53.3 0.8 1.6 1 0 0 1 1 1 1 Spo12 family IGPD PF00475.18 EEQ34096.1 - 2.5e-58 196.5 1.4 3.8e-58 195.9 1.4 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Acyl-CoA_dh_1 PF00441.24 EEQ34097.1 - 1e-30 107.0 2.6 1e-30 107.0 2.6 1.7 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EEQ34097.1 - 2.7e-18 65.9 0.0 5e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EEQ34097.1 - 4e-14 53.2 0.3 9.5e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EEQ34097.1 - 4e-14 53.0 5.7 8.4e-14 52.0 5.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain EST1_DNA_bind PF10373.9 EEQ34098.1 - 1.7e-62 211.5 5.3 2.6e-62 210.8 5.3 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EEQ34098.1 - 1.3e-22 80.9 0.7 1.3e-22 80.9 0.7 2.4 3 0 0 3 3 3 1 Telomerase activating protein Est1 PfkB PF00294.24 EEQ34099.1 - 3.2e-67 227.0 0.0 3.9e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EEQ34099.1 - 3.6e-05 23.3 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PS_pyruv_trans PF04230.13 EEQ34099.1 - 0.0044 17.0 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase DUF1770 PF08589.10 EEQ34100.1 - 8.1e-17 62.0 0.2 1.2e-16 61.4 0.2 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 EEQ34101.1 - 2.3e-06 27.0 0.0 5.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ribosomal_L2_C PF03947.18 EEQ34102.1 - 3.5e-41 140.3 6.1 3.5e-41 140.3 6.1 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EEQ34102.1 - 1.1e-12 47.7 0.1 2.9e-12 46.4 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ada_Zn_binding PF02805.16 EEQ34103.1 - 3.4e-30 103.8 4.9 6.2e-30 103.0 4.9 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 EEQ34103.1 - 3.1e-07 30.3 0.0 6.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EEQ34103.1 - 0.00038 20.7 0.0 0.0008 19.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain SUIM_assoc PF16619.5 EEQ34103.1 - 0.00055 19.9 0.9 0.00055 19.9 0.9 2.1 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 EEQ34103.1 - 0.2 11.6 8.4 0.29 11.1 8.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 EEQ34103.1 - 0.66 8.5 2.2 0.87 8.1 2.2 1.1 1 0 0 1 1 1 0 Macoilin family BAR PF03114.18 EEQ34104.1 - 3e-43 148.2 6.6 3.7e-43 147.9 6.6 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EEQ34104.1 - 5.7e-07 28.9 3.1 6.5e-07 28.8 3.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking HSA PF07529.13 EEQ34105.1 - 3.5e-20 72.1 10.1 3.5e-20 72.1 10.1 3.3 3 1 1 4 4 4 1 HSA QLQ PF08880.11 EEQ34105.1 - 6.1e-13 48.3 3.8 6.1e-13 48.3 3.8 3.3 4 0 0 4 4 4 1 QLQ Bromodomain PF00439.25 EEQ34106.1 - 4e-27 94.1 1.1 6e-26 90.3 0.9 2.4 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.6 EEQ34106.1 - 1.6e-13 51.1 0.1 1.6e-13 51.1 0.1 3.4 3 2 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Pro_dh PF01619.18 EEQ34106.1 - 1.4 8.4 6.6 0.17 11.4 2.3 1.7 2 1 0 2 2 2 0 Proline dehydrogenase DinB PF05163.12 EEQ34106.1 - 2.9 7.8 8.1 3.1 7.7 0.7 3.0 3 0 0 3 3 3 0 DinB family Aminotran_1_2 PF00155.21 EEQ34109.1 - 7.6e-85 285.2 0.0 9.9e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEQ34109.1 - 2.1e-06 26.5 0.0 3.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EEQ34109.1 - 1.4e-05 24.6 0.1 2.3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EEQ34109.1 - 0.00089 18.3 0.0 0.0019 17.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EEQ34109.1 - 0.021 14.1 0.6 0.057 12.7 0.7 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase RNA_pol_I_A49 PF06870.12 EEQ34110.1 - 2.4e-70 237.4 0.1 2.8e-70 237.2 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Ribosomal_S2 PF00318.20 EEQ34110.1 - 0.066 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 Ribosomal_L41 PF05162.13 EEQ34111.1 - 4.9e-09 36.1 26.3 8e-09 35.4 26.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L41 GATase PF00117.28 EEQ34112.1 - 7.4e-47 159.6 0.0 1.2e-46 158.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EEQ34112.1 - 8e-45 151.8 0.0 3.6e-44 149.7 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EEQ34112.1 - 6.4e-05 22.8 0.5 0.0011 18.7 0.2 2.4 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 EEQ34112.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family MscS_TM PF12794.7 EEQ34113.1 - 0.026 13.4 0.8 0.03 13.2 0.8 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Peptidase_S10 PF00450.22 EEQ34114.1 - 4.9e-90 302.9 9.1 9.2e-90 302.0 9.1 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_3 PF13302.7 EEQ34115.1 - 1.6e-10 41.8 0.0 2.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ34115.1 - 0.00015 22.0 0.0 0.0021 18.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family PARP PF00644.20 EEQ34116.1 - 1.4e-61 207.5 0.0 1.4e-61 207.5 0.0 2.7 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EEQ34116.1 - 2e-45 154.2 0.4 3.2e-45 153.6 0.4 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EEQ34116.1 - 8e-24 83.5 0.1 3.4e-23 81.5 0.1 2.2 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 EEQ34116.1 - 7.5e-10 39.1 0.0 2.1e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EEQ34116.1 - 9.5e-08 31.9 0.1 1.9e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EEQ34116.1 - 2.3e-05 24.7 0.0 6.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain SOG2 PF10428.9 EEQ34116.1 - 0.66 9.1 7.4 1.1 8.4 7.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ysc84 PF04366.12 EEQ34117.1 - 3.2e-46 156.2 0.0 5.2e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Antimicrobial10 PF08105.11 EEQ34117.1 - 0.02 14.9 0.2 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 Metchnikowin family ETF PF01012.21 EEQ34118.1 - 6e-40 137.1 1.0 7.6e-40 136.7 1.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Flavodoxin_1 PF00258.25 EEQ34119.1 - 2.7e-32 111.9 0.0 2.1e-31 109.1 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 EEQ34119.1 - 3.3e-29 102.1 0.0 5.3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EEQ34119.1 - 1.1e-13 51.8 0.0 2.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EEQ34119.1 - 0.00016 21.9 0.0 0.25 11.6 0.0 2.9 2 1 1 3 3 3 2 Flavodoxin domain Flavodoxin_3 PF12641.7 EEQ34119.1 - 0.018 14.7 0.0 0.092 12.4 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.8 EEQ34121.1 - 1.9e-54 185.3 12.8 2.3e-54 185.1 12.8 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 MitMem_reg PF13012.6 EEQ34123.1 - 2.7e-11 43.9 1.0 9e-11 42.2 1.0 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EEQ34123.1 - 1.5e-10 41.0 0.0 3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease KAsynt_C_assoc PF16197.5 EEQ34123.1 - 0.0092 16.4 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension RSB_motif PF16294.5 EEQ34124.1 - 1.6e-08 34.7 0.0 1.6e-08 34.7 0.0 3.7 2 1 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 EEQ34124.1 - 3.9e-08 32.9 0.2 8.8e-08 31.7 0.2 1.6 1 0 0 1 1 1 1 SAP domain Pinin_SDK_memA PF04696.13 EEQ34124.1 - 0.095 12.8 0.0 0.095 12.8 0.0 3.4 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region SCIMP PF15050.6 EEQ34124.1 - 6.5 7.2 6.0 22 5.5 6.0 1.9 1 0 0 1 1 1 0 SCIMP protein DUF1772 PF08592.11 EEQ34125.1 - 0.0019 18.5 1.1 0.0069 16.7 1.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF401 PF04165.12 EEQ34125.1 - 0.095 12.0 2.5 0.13 11.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) adh_short_C2 PF13561.6 EEQ34126.1 - 5e-34 117.9 5.3 2.1e-33 115.9 5.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ34126.1 - 6e-28 97.6 1.9 1e-27 96.9 1.9 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ34126.1 - 1.1e-06 28.7 0.9 2.2e-06 27.7 0.2 1.7 2 0 0 2 2 2 1 KR domain HMMR_N PF15905.5 EEQ34127.1 - 0.0021 17.6 10.9 0.0021 17.6 10.9 2.0 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal DUF4200 PF13863.6 EEQ34127.1 - 0.0029 18.0 4.2 0.0029 18.0 4.2 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) APC_N_CC PF16689.5 EEQ34127.1 - 0.01 15.9 1.1 0.027 14.5 1.1 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain DUF3584 PF12128.8 EEQ34127.1 - 0.019 12.5 12.8 0.033 11.7 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1192 PF06698.11 EEQ34127.1 - 0.082 13.0 4.1 4 7.6 3.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Cast PF10174.9 EEQ34127.1 - 0.093 10.9 16.5 0.032 12.5 13.3 1.7 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone CENP-Q PF13094.6 EEQ34127.1 - 0.19 11.9 16.9 0.6 10.3 16.9 1.8 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.8 EEQ34127.1 - 0.22 11.6 15.9 0.11 12.6 5.0 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding XkdW PF09636.10 EEQ34127.1 - 0.23 11.6 2.4 1.3 9.1 0.3 3.2 3 0 0 3 3 3 0 XkdW protein AAA_13 PF13166.6 EEQ34127.1 - 0.24 10.0 12.4 0.27 9.8 6.0 1.9 1 1 1 2 2 2 0 AAA domain Fez1 PF06818.15 EEQ34127.1 - 0.28 11.6 24.4 0.033 14.6 13.8 2.9 2 1 1 3 3 3 0 Fez1 CREPT PF16566.5 EEQ34127.1 - 0.67 10.1 11.9 0.04 14.1 3.8 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HMMR_C PF15908.5 EEQ34127.1 - 0.75 10.0 11.8 3.5 7.9 7.1 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal FmiP_Thoc5 PF09766.9 EEQ34127.1 - 0.76 9.0 14.4 0.18 11.1 8.2 2.8 2 1 1 3 3 3 0 Fms-interacting protein/Thoc5 Metal_resist PF13801.6 EEQ34127.1 - 1.2 9.3 10.6 1.6 8.9 6.3 3.2 2 0 0 2 2 2 0 Heavy-metal resistance YabA PF06156.13 EEQ34127.1 - 2 9.1 10.8 3.3 8.4 2.7 3.3 1 1 2 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 EEQ34127.1 - 4.8 7.2 26.4 0.13 12.3 3.5 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 EEQ34127.1 - 5.1 6.1 15.2 7.8 5.5 14.0 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SOGA PF11365.8 EEQ34127.1 - 5.7 8.1 15.3 0.29 12.3 1.4 3.7 1 1 2 3 3 3 0 Protein SOGA DUF1515 PF07439.11 EEQ34127.1 - 7.3 6.7 7.1 1.2 9.2 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) RabGAP-TBC PF00566.18 EEQ34129.1 - 2.3e-46 158.2 0.0 3.6e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EEQ34129.1 - 5.9e-07 28.9 2.7 0.0068 16.3 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EEQ34129.1 - 9.1e-07 28.0 1.4 0.012 15.1 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EEQ34129.1 - 0.00074 19.9 0.4 0.0044 17.4 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair GRAM PF02893.20 EEQ34129.1 - 0.0019 18.0 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_5 PF13202.6 EEQ34129.1 - 0.063 12.8 1.4 4.1 7.1 0.5 2.8 2 0 0 2 2 2 0 EF hand DUF4611 PF15387.6 EEQ34129.1 - 1.6 9.0 10.9 3.8 7.8 1.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CNH PF00780.22 EEQ34130.1 - 2.9e-65 220.6 0.0 4.6e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EEQ34130.1 - 9.7e-34 117.2 1.4 1.9e-33 116.2 1.4 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EEQ34130.1 - 1.9e-14 53.9 0.0 6.8e-14 52.1 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EEQ34130.1 - 0.0031 18.0 0.0 0.014 15.9 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 EEQ34130.1 - 0.0049 16.7 0.1 3.5 7.5 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_13 PF16652.5 EEQ34130.1 - 0.11 12.3 0.4 1.8 8.4 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain 2OG-FeII_Oxy_2 PF13532.6 EEQ34131.1 - 2.4e-21 76.8 0.0 8.1e-21 75.1 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 EEQ34132.1 - 5.5e-76 255.8 0.0 7.4e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ34132.1 - 2.1e-13 51.0 0.1 4.5e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 EEQ34133.1 - 2.2e-18 66.3 10.5 0.0037 18.1 0.0 8.3 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ34133.1 - 2.7e-07 30.8 0.0 0.00035 20.8 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ34133.1 - 0.093 11.7 0.3 0.73 8.7 0.1 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 EEQ34133.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus NDUF_B12 PF08122.12 EEQ34134.1 - 7.4e-27 93.2 1.5 1e-26 92.7 1.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.20 EEQ34135.1 - 8.9e-25 87.5 0.1 2e-11 43.7 0.0 2.8 3 0 0 3 3 3 2 CAF1 family ribonuclease DUF2722 PF10846.8 EEQ34135.1 - 1.1 8.1 8.6 0.11 11.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) ANAPC_CDC26 PF10471.9 EEQ34135.1 - 1.3 9.9 16.3 2.3 9.1 0.8 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Asp PF00026.23 EEQ34136.1 - 2e-49 168.7 0.0 7.6e-26 91.3 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEQ34136.1 - 0.0015 18.8 0.3 0.29 11.4 0.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EEQ34136.1 - 0.023 15.3 0.1 2.8 8.7 0.1 3.2 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 EEQ34136.1 - 0.037 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal TPR_2 PF07719.17 EEQ34137.1 - 4.6e-06 26.3 5.1 0.023 14.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ34137.1 - 0.00087 19.0 2.4 1.4 8.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ34137.1 - 0.018 15.4 7.2 0.15 12.4 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ34137.1 - 0.028 14.9 1.4 0.59 10.7 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ34137.1 - 0.56 10.6 2.7 15 6.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ34137.1 - 1.7 8.9 4.0 95 3.4 0.9 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat VASt PF16016.5 EEQ34138.1 - 2e-36 125.7 0.0 3.8e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EEQ34138.1 - 3e-21 75.4 0.0 5.4e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DAO_C PF16901.5 EEQ34139.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase BMFP PF04380.13 EEQ34139.1 - 0.098 13.2 0.8 0.38 11.3 0.5 2.2 2 0 0 2 2 2 0 Membrane fusogenic activity DUF812 PF05667.11 EEQ34139.1 - 0.11 11.3 3.5 0.11 11.4 2.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) bZIP_1 PF00170.21 EEQ34139.1 - 0.45 10.7 7.6 2.2 8.4 3.7 2.7 2 0 0 2 2 2 0 bZIP transcription factor DHR10 PF18595.1 EEQ34139.1 - 0.46 10.5 11.6 0.028 14.5 5.2 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 EEQ34139.1 - 0.48 10.5 4.7 4.3 7.4 1.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 EEQ34139.1 - 0.53 10.9 3.7 4.3 8.0 0.4 2.7 2 0 0 2 2 2 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 EEQ34139.1 - 0.63 10.3 6.0 0.62 10.4 3.6 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 EEQ34139.1 - 2.5 7.9 9.5 0.95 9.3 6.1 2.1 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 EEQ34139.1 - 4.5 7.7 8.1 0.82 10.1 2.8 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 EEQ34139.1 - 5.2 6.7 12.3 2.3 7.8 1.9 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 EEQ34139.1 - 9.2 5.6 8.6 2.9 7.2 4.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mg_trans_NIPA PF05653.14 EEQ34140.1 - 1e-63 215.2 13.3 2.2e-61 207.6 10.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA SLC35F PF06027.12 EEQ34140.1 - 0.00024 20.7 0.3 0.00024 20.7 0.3 1.8 1 1 1 2 2 2 1 Solute carrier family 35 EamA PF00892.20 EEQ34140.1 - 0.001 19.2 0.7 0.001 19.2 0.7 3.7 3 1 0 3 3 3 1 EamA-like transporter family RNA_capsid PF03035.14 EEQ34140.1 - 0.052 13.6 0.7 0.12 12.4 0.7 1.6 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein DUF2198 PF09964.9 EEQ34140.1 - 3.3 7.8 7.3 0.28 11.3 1.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) TssN PF17555.2 EEQ34140.1 - 4.3 6.6 9.7 7.3 5.9 9.7 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN DoxX_2 PF13564.6 EEQ34140.1 - 5.2 7.2 11.5 1.4 9.1 0.6 3.1 4 0 0 4 4 4 0 DoxX-like family WD40 PF00400.32 EEQ34141.1 - 1.6e-07 31.9 5.3 0.0043 17.9 0.3 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat AAA PF00004.29 EEQ34142.1 - 8.5e-41 139.5 0.0 1.6e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ34142.1 - 1.2e-09 37.9 0.5 2.5e-09 36.8 0.5 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EEQ34142.1 - 1.5e-09 37.7 0.1 2.8e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EEQ34142.1 - 8.1e-06 26.2 0.4 0.068 13.4 0.2 2.6 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 EEQ34142.1 - 1.3e-05 25.4 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EEQ34142.1 - 5.4e-05 22.5 0.0 9.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EEQ34142.1 - 0.0001 22.3 0.0 0.00029 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEQ34142.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEQ34142.1 - 0.0013 19.2 0.5 0.032 14.6 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EEQ34142.1 - 0.0022 18.3 0.4 0.0065 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EEQ34142.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EEQ34142.1 - 0.023 14.0 0.4 0.35 10.2 0.2 2.2 1 1 0 2 2 2 0 KaiC TIP49 PF06068.13 EEQ34142.1 - 0.025 13.8 1.4 0.042 13.1 0.1 2.0 2 1 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 EEQ34142.1 - 0.031 14.8 0.0 0.07 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EEQ34142.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EEQ34142.1 - 0.049 13.5 0.7 1.4 8.8 0.2 2.8 2 1 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 EEQ34142.1 - 0.059 12.6 0.0 0.19 11.0 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EEQ34142.1 - 0.073 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EEQ34142.1 - 0.091 12.2 1.1 0.94 8.9 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 EEQ34142.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EEQ34142.1 - 0.096 12.4 3.8 0.41 10.3 0.5 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EEQ34142.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EEQ34142.1 - 0.12 12.7 0.4 0.37 11.1 0.4 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EEQ34142.1 - 0.13 11.5 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 EEQ34142.1 - 0.14 11.5 0.1 0.29 10.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_pol_Rpb1_5 PF04998.17 EEQ34142.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Prot_ATP_OB_N PF17758.1 EEQ34142.1 - 0.16 11.7 0.7 0.84 9.3 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain ABC_tran PF00005.27 EEQ34142.1 - 0.19 12.2 0.6 1.4 9.5 0.6 2.4 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 EEQ34142.1 - 2.9 7.5 4.7 0.51 10.0 0.5 2.0 2 1 0 2 2 1 0 AAA domain APH PF01636.23 EEQ34143.1 - 5e-12 46.3 0.0 3.8e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family UQ_con PF00179.26 EEQ34144.1 - 2e-44 150.7 0.0 2.5e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ34144.1 - 1.7e-05 24.5 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_3 PF09288.10 EEQ34144.1 - 3.1e-05 23.7 0.0 6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.22 EEQ34144.1 - 0.043 14.1 0.0 0.068 13.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EEQ34144.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Cyclin_C_2 PF16899.5 EEQ34145.1 - 3.1e-35 120.7 0.4 8.3e-32 109.7 0.0 2.7 3 0 0 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EEQ34145.1 - 2e-05 24.4 0.0 7.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain ABC_tran PF00005.27 EEQ34146.1 - 2e-48 164.4 0.0 1.7e-23 83.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EEQ34146.1 - 3.6e-21 75.0 2.4 3.6e-21 75.0 2.4 2.7 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 EEQ34146.1 - 2.5e-19 70.2 0.2 0.00063 19.6 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ34146.1 - 3e-11 43.2 0.3 0.00056 19.4 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ34146.1 - 1.3e-08 34.4 0.4 0.0027 17.4 0.1 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EEQ34146.1 - 7.4e-07 29.2 0.1 0.018 14.8 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ34146.1 - 1.1e-06 28.7 0.1 0.0043 17.0 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_28 PF13521.6 EEQ34146.1 - 2.3e-06 28.0 0.0 0.0012 19.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ34146.1 - 2.6e-06 27.9 0.0 0.018 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EEQ34146.1 - 6e-06 26.3 0.0 0.02 15.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EEQ34146.1 - 1.3e-05 25.9 12.5 0.019 15.4 0.1 4.1 5 0 0 5 5 3 2 AAA domain AAA_18 PF13238.6 EEQ34146.1 - 1.6e-05 25.4 0.1 0.073 13.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EEQ34146.1 - 2e-05 24.8 0.0 0.17 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EEQ34146.1 - 2.3e-05 24.1 0.0 0.029 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EEQ34146.1 - 4.9e-05 23.8 0.0 0.68 10.4 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EEQ34146.1 - 0.00015 21.7 0.1 0.26 11.2 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_5 PF07728.14 EEQ34146.1 - 0.00022 21.2 0.1 0.77 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EEQ34146.1 - 0.00023 21.5 0.4 1.5 9.2 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_33 PF13671.6 EEQ34146.1 - 0.00026 21.2 1.0 0.24 11.5 0.1 3.3 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 EEQ34146.1 - 0.00031 20.9 1.6 0.69 10.0 0.0 3.8 3 1 1 4 4 4 1 Dynamin family NB-ARC PF00931.22 EEQ34146.1 - 0.00086 18.6 0.3 2.1 7.5 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain Roc PF08477.13 EEQ34146.1 - 0.0014 18.8 0.1 2.6 8.3 0.1 3.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EEQ34146.1 - 0.0038 17.0 1.5 2.5 7.8 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 EEQ34146.1 - 0.0042 17.1 0.0 4.4 7.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EEQ34146.1 - 0.0043 16.3 0.0 0.4 9.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 EEQ34146.1 - 0.0082 15.7 0.0 1.3 8.5 0.0 3.2 3 1 1 4 4 4 1 AAA domain AAA_7 PF12775.7 EEQ34146.1 - 0.01 15.4 0.4 1.4 8.4 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF2813 PF11398.8 EEQ34146.1 - 0.016 14.5 1.0 2 7.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) NTPase_1 PF03266.15 EEQ34146.1 - 0.023 14.6 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 NTPase MCM PF00493.23 EEQ34146.1 - 0.027 13.6 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain ATPase_2 PF01637.18 EEQ34146.1 - 0.033 14.1 0.1 5.9 6.7 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea GST_C_3 PF14497.6 EEQ34146.1 - 0.037 14.2 0.1 0.089 13.0 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_17 PF13207.6 EEQ34146.1 - 0.043 14.2 0.3 28 5.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 EEQ34146.1 - 0.063 13.2 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain DAP3 PF10236.9 EEQ34146.1 - 0.063 12.4 0.7 3.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TsaE PF02367.17 EEQ34146.1 - 0.065 13.2 0.5 14 5.7 0.0 3.1 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EEQ34146.1 - 0.12 12.1 2.5 3.2 7.4 0.1 3.1 3 1 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 EEQ34146.1 - 0.14 11.9 1.2 7.7 6.3 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation HPP PF04982.13 EEQ34147.1 - 1.6e-39 134.8 6.7 3e-39 133.9 6.7 1.4 1 0 0 1 1 1 1 HPP family DUF599 PF04654.12 EEQ34147.1 - 0.11 11.9 1.0 11 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF599 Yip1 PF04893.17 EEQ34147.1 - 0.32 10.7 9.9 1.6 8.4 4.1 2.6 1 1 2 3 3 3 0 Yip1 domain GFO_IDH_MocA PF01408.22 EEQ34149.1 - 2.9e-24 86.2 0.1 5.3e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EEQ34149.1 - 6.3e-14 52.0 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EEQ34149.1 - 7.7e-07 29.8 0.2 1.5e-06 28.9 0.2 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EEQ34149.1 - 0.00035 20.7 0.0 0.00058 20.0 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 EEQ34149.1 - 0.00088 19.9 0.2 0.0029 18.3 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain OCD_Mu_crystall PF02423.15 EEQ34149.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family CBP_BcsQ PF06564.12 EEQ34149.1 - 0.015 14.8 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Semialdhyde_dh PF01118.24 EEQ34149.1 - 0.036 14.5 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 EEQ34149.1 - 0.062 13.8 0.2 0.15 12.6 0.2 1.6 2 0 0 2 2 2 0 CoA binding domain MARVEL PF01284.23 EEQ34150.1 - 0.00012 22.1 2.4 0.00021 21.3 2.4 1.4 1 0 0 1 1 1 1 Membrane-associating domain SR-25 PF10500.9 EEQ34151.1 - 0.0027 17.4 5.2 0.0053 16.4 5.2 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein NAM-associated PF14303.6 EEQ34151.1 - 6.8 7.4 12.3 0.25 12.1 5.8 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain RRM_1 PF00076.22 EEQ34153.1 - 2.7e-15 55.9 0.1 4.5e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.6 EEQ34155.1 - 3.2e-07 30.5 8.1 1.6e-05 25.1 1.4 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 EEQ34155.1 - 0.00014 22.0 4.6 0.00029 21.1 4.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EEQ34155.1 - 0.0002 21.9 15.0 0.018 15.9 5.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ34155.1 - 0.0015 18.8 4.8 0.08 13.3 1.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EEQ34155.1 - 0.029 14.8 14.5 0.12 12.9 7.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 EEQ34155.1 - 0.73 10.3 5.0 4.3 7.9 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type QCR10 PF09796.9 EEQ34156.1 - 2.2e-23 82.1 0.1 3e-23 81.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) APG5 PF04106.12 EEQ34157.1 - 2.3e-67 226.9 0.0 2.8e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SelP_N PF04592.14 EEQ34158.1 - 0.42 10.0 11.7 0.57 9.5 11.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 EEQ34158.1 - 3.8 5.9 12.6 4.7 5.7 12.6 1.1 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 EEQ34159.1 - 6.3e-18 64.8 57.4 6.3e-18 64.8 57.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Arrestin_N PF00339.29 EEQ34161.1 - 7.2e-15 55.3 3.6 2.5e-14 53.6 0.0 3.3 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain HRXXH PF13933.6 EEQ34162.1 - 4.5e-05 23.1 0.2 0.00015 21.4 0.2 1.8 1 1 0 1 1 1 1 Putative peptidase family CLZ PF16526.5 EEQ34163.1 - 2.3 8.6 7.4 0.54 10.7 0.8 3.1 2 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SHR3_chaperone PF08229.11 EEQ34164.1 - 9.1e-81 269.3 0.0 1.1e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 Phage_holin_2_4 PF16082.5 EEQ34164.1 - 0.12 12.2 1.9 0.2 11.4 0.6 2.1 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like ArfGap PF01412.18 EEQ34166.1 - 1.5e-31 108.8 0.0 1.6e-30 105.5 0.1 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.27 EEQ34167.1 - 2.9e-55 186.9 0.0 4.7e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EEQ34167.1 - 2.8e-24 85.0 0.0 6.2e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EEQ34167.1 - 4e-17 62.0 0.1 6.3e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEQ34167.1 - 5.2e-07 30.0 0.0 3.4e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EEQ34167.1 - 8.4e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 EEQ34167.1 - 0.0011 18.8 0.1 0.91 9.3 0.0 2.7 1 1 0 2 2 2 2 Elongation factor G, domain IV Vps5 PF09325.10 EEQ34168.1 - 4.1e-11 42.9 3.0 7.4e-11 42.0 3.0 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EEQ34168.1 - 8.6e-09 35.4 0.0 1.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 PX domain GFA PF04828.14 EEQ34169.1 - 9.4e-16 57.9 0.1 1.6e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme THOC2_N PF16134.5 EEQ34170.1 - 3.7e-173 577.5 0.1 1e-147 493.5 0.0 2.8 3 0 0 3 3 3 2 THO complex subunit 2 N-terminus Tho2 PF11262.8 EEQ34170.1 - 4.2e-107 357.8 0.0 6.5e-107 357.2 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EEQ34170.1 - 5.7e-30 103.2 0.3 1.6e-29 101.8 0.0 1.9 2 0 0 2 2 2 1 Transcription- and export-related complex subunit MFS_1 PF07690.16 EEQ34172.1 - 7.6e-35 120.5 26.0 1.2e-34 119.8 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ34172.1 - 3.3e-10 39.4 15.6 5.5e-10 38.7 15.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Gly_transf_sug PF04488.15 EEQ34173.1 - 2.4e-18 66.6 0.1 1.2e-17 64.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EEQ34173.1 - 0.0018 17.7 0.2 0.0066 15.9 0.1 1.8 2 0 0 2 2 2 1 Capsular polysaccharide synthesis protein BPD_transp_1 PF00528.22 EEQ34173.1 - 0.0034 17.1 4.7 0.11 12.2 0.3 2.3 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component Abhydrolase_1 PF00561.20 EEQ34174.1 - 2.2e-47 161.9 0.0 4.4e-47 160.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ34174.1 - 0.00034 21.3 4.4 0.002 18.8 4.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family MIOX PF05153.15 EEQ34178.1 - 1.8e-123 411.0 2.4 2.1e-123 410.7 2.4 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase NOG1_N PF17835.1 EEQ34178.1 - 0.023 14.6 2.6 0.19 11.7 0.1 2.6 2 1 1 3 3 3 0 NOG1 N-terminal helical domain DUF1796 PF08795.10 EEQ34178.1 - 0.04 13.9 0.3 0.068 13.1 0.3 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) HD PF01966.22 EEQ34178.1 - 0.086 13.1 0.9 0.98 9.6 0.0 2.6 3 0 0 3 3 3 0 HD domain Exo_endo_phos PF03372.23 EEQ34179.1 - 0.00062 19.3 0.0 0.0013 18.3 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RTC PF01137.21 EEQ34180.1 - 1e-41 142.6 0.0 4.5e-41 140.5 0.0 1.8 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase BAR PF03114.18 EEQ34183.1 - 2.7e-13 50.1 0.2 3.8e-13 49.6 0.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EEQ34183.1 - 2.1e-12 46.4 0.1 3.8e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ34183.1 - 4.9e-12 45.5 0.1 9.6e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ34183.1 - 3e-09 36.4 0.1 9.8e-09 34.8 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain U1snRNP70_N PF12220.8 EEQ34183.1 - 2.6 8.8 11.5 1.6 9.4 3.5 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2439 PF10382.9 EEQ34184.1 - 3.9e-25 88.0 0.0 7.3e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Methyltransf_23 PF13489.6 EEQ34185.1 - 5.5e-14 52.3 0.0 8.5e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ34185.1 - 1.1e-06 29.3 0.0 1.7e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ34185.1 - 1.1e-06 29.2 0.0 4.2e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ34185.1 - 3.9e-06 26.7 0.0 7.4e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ34185.1 - 0.0006 20.5 0.0 0.0069 17.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain GH101_N PF17995.1 EEQ34185.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal Mcp5_PH PF12814.7 EEQ34186.1 - 1.9e-44 150.7 0.4 3.5e-44 149.8 0.4 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EEQ34186.1 - 9.9e-05 22.8 0.0 0.00022 21.7 0.0 1.6 1 0 0 1 1 1 1 PH domain TetR_C_21 PF17926.1 EEQ34186.1 - 1.6 8.9 7.5 0.34 11.1 0.9 3.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1664 PF07889.12 EEQ34186.1 - 6.5 6.8 15.6 4.9 7.2 2.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) zf-C3HC4_3 PF13920.6 EEQ34187.1 - 3.2e-08 33.3 5.4 5.5e-08 32.6 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 EEQ34187.1 - 6.7e-08 32.3 2.3 1.3e-07 31.4 2.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 EEQ34187.1 - 1e-06 28.5 7.7 1.8e-06 27.7 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ34187.1 - 3.1e-06 27.1 8.4 5.2e-06 26.3 8.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEQ34187.1 - 3.2e-06 27.1 7.9 6.2e-06 26.1 7.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EEQ34187.1 - 3.6e-06 26.7 10.0 6.4e-06 25.9 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ34187.1 - 1.5e-05 25.2 6.6 2.9e-05 24.3 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 EEQ34187.1 - 2.8e-05 24.2 3.6 2.8e-05 24.2 3.6 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf_CCCH_4 PF18345.1 EEQ34187.1 - 3e-05 23.9 5.6 7e-05 22.7 5.6 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EEQ34187.1 - 0.002 17.9 1.9 0.002 17.9 1.9 1.7 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 EEQ34187.1 - 0.0077 16.1 6.5 0.014 15.2 6.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EEQ34187.1 - 0.016 15.3 8.1 0.037 14.2 8.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EEQ34187.1 - 0.097 13.0 4.2 0.21 11.9 4.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain SH3-RhoG_link PF16609.5 EEQ34187.1 - 0.12 12.0 3.4 0.25 11.1 3.4 1.5 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region zf-Nse PF11789.8 EEQ34187.1 - 0.46 10.3 2.6 0.83 9.5 2.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3431 PF11913.8 EEQ34188.1 - 7.7e-81 271.0 0.4 9.6e-81 270.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Myb_DNA-bind_6 PF13921.6 EEQ34189.1 - 0.00091 19.4 0.1 0.0052 17.0 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase PF00069.25 EEQ34190.1 - 2e-57 194.6 0.0 3e-53 180.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34190.1 - 4.8e-28 98.1 0.1 2.4e-26 92.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 EEQ34190.1 - 1.1e-07 32.1 0.0 2.9e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EEQ34190.1 - 2.4e-05 23.3 0.0 6.7e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EEQ34190.1 - 0.00063 19.2 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ34190.1 - 0.00088 18.7 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ34190.1 - 0.0015 18.5 0.0 0.0033 17.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EEQ34190.1 - 0.0047 15.9 0.2 0.009 15.0 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain p450 PF00067.22 EEQ34191.1 - 1.4e-66 225.2 0.0 1.7e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 P2X_receptor PF00864.19 EEQ34192.1 - 0.016 14.3 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 ATP P2X receptor bVLRF1 PF18826.1 EEQ34193.1 - 4.4e-62 208.4 0.2 1e-61 207.2 0.2 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EEQ34193.1 - 3.4e-05 24.1 0.0 7.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EEQ34193.1 - 0.00061 20.1 0.2 0.0016 18.8 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EEQ34193.1 - 0.0024 18.2 0.0 0.0082 16.6 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EEQ34193.1 - 0.0064 17.1 0.0 0.02 15.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ34193.1 - 0.06 14.0 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) ABC_membrane PF00664.23 EEQ34194.1 - 3.5e-86 289.2 31.4 9.8e-47 159.9 12.3 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ34194.1 - 3.7e-51 173.2 0.0 1.5e-30 106.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ34194.1 - 4.6e-09 36.0 3.6 0.00047 19.7 0.1 4.1 2 2 2 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EEQ34194.1 - 1.1e-06 28.6 0.5 0.052 13.6 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ34194.1 - 4.4e-06 26.7 0.4 0.0036 17.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EEQ34194.1 - 1.2e-05 25.7 1.4 0.014 15.8 0.8 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EEQ34194.1 - 0.0011 18.6 0.2 1.6 8.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 EEQ34194.1 - 0.0016 18.2 0.3 2.1 8.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EEQ34194.1 - 0.0024 17.7 0.9 0.67 9.7 0.1 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 EEQ34194.1 - 0.005 16.9 0.5 0.7 9.9 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 EEQ34194.1 - 0.0059 17.1 1.3 0.54 10.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 EEQ34194.1 - 0.0095 16.1 4.5 22 5.3 0.0 4.3 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EEQ34194.1 - 0.021 14.9 2.9 3.1 7.8 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain DUF720 PF05302.11 EEQ34194.1 - 0.049 13.5 0.3 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF720) IstB_IS21 PF01695.17 EEQ34194.1 - 0.063 13.0 1.9 4.5 7.0 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein DUP PF00674.18 EEQ34194.1 - 0.071 13.3 0.5 0.36 11.0 0.5 2.3 1 0 0 1 1 1 0 DUP family RNA_helicase PF00910.22 EEQ34194.1 - 0.084 13.3 0.0 5.8 7.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EEQ34194.1 - 0.13 12.5 4.9 4.4 7.6 0.3 3.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EEQ34194.1 - 2.4 8.6 4.4 2.9 8.3 0.2 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EEQ34194.1 - 4.2 7.3 6.4 6.6 6.6 0.1 3.2 3 0 0 3 3 3 0 NACHT domain DUF2841 PF11001.8 EEQ34196.1 - 3.8e-53 178.8 0.1 6.3e-53 178.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) CorA PF01544.18 EEQ34196.1 - 0.1 11.9 0.2 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mpt_N PF09176.11 EEQ34197.1 - 0.22 11.7 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Zip PF02535.22 EEQ34198.1 - 4.2e-49 167.6 4.3 6.6e-49 166.9 4.3 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter SAC3_GANP PF03399.16 EEQ34199.1 - 1.6e-104 349.4 4.9 1.6e-104 349.4 4.9 2.2 3 0 0 3 3 3 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EEQ34199.1 - 5.2e-05 23.3 0.4 0.00014 21.8 0.4 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family CN_hydrolase PF00795.22 EEQ34200.1 - 2.6e-12 46.7 0.0 7.2e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase HLH PF00010.26 EEQ34201.1 - 5.7e-12 45.4 1.2 1.1e-11 44.5 1.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DASH_Dad4 PF08650.10 EEQ34201.1 - 0.034 14.1 0.6 0.14 12.1 0.6 2.2 1 1 0 1 1 1 0 DASH complex subunit Dad4 Mobilization_B PF17511.2 EEQ34201.1 - 0.9 9.9 6.8 0.08 13.3 0.9 2.1 1 1 1 2 2 2 0 Mobilization protein B DUF2681 PF10883.8 EEQ34201.1 - 5.7 7.4 7.1 3.4 8.1 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Peptidase_S64 PF08192.11 EEQ34202.1 - 0.00037 19.1 2.7 0.00095 17.8 2.7 1.7 1 1 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.6 EEQ34202.1 - 0.0062 17.4 0.0 0.037 14.9 0.0 2.2 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 EEQ34202.1 - 0.0099 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 DUF5043 PF16446.5 EEQ34202.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5043) Peptidase_S7 PF00949.21 EEQ34202.1 - 0.12 12.2 0.1 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease BTB_2 PF02214.22 EEQ34203.1 - 2.1e-07 31.2 0.0 4.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EEQ34203.1 - 1.1e-05 25.6 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain polyprenyl_synt PF00348.17 EEQ34204.1 - 2.6e-66 223.3 0.0 3.2e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1771 PF08590.10 EEQ34205.1 - 2.2e-24 85.6 4.6 2.2e-24 85.6 4.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EEQ34205.1 - 4.2e-11 43.1 0.4 1.2e-10 41.6 0.4 1.8 1 0 0 1 1 1 1 Smr domain Connexin43 PF03508.13 EEQ34205.1 - 0.6 9.7 3.3 0.45 10.1 0.8 2.0 2 0 0 2 2 2 0 Gap junction alpha-1 protein (Cx43) Pyrid_oxidase_2 PF13883.6 EEQ34206.1 - 7.2e-35 120.5 0.0 1e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ipi1_N PF12333.8 EEQ34208.1 - 2.8e-27 95.3 0.0 2.8e-27 95.3 0.0 2.6 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.17 EEQ34209.1 - 6.2e-05 22.7 0.1 0.12 12.2 0.0 2.9 3 0 0 3 3 3 2 Roadblock/LC7 domain CEND1 PF15677.5 EEQ34209.1 - 0.62 10.6 6.5 0.81 10.2 6.5 1.2 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 YtxH PF12732.7 EEQ34210.1 - 0.019 15.5 1.8 0.025 15.1 1.8 1.3 1 0 0 1 1 1 0 YtxH-like protein ISG65-75 PF11727.8 EEQ34210.1 - 0.06 12.6 0.9 0.068 12.4 0.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Aa_trans PF01490.18 EEQ34212.1 - 1.9e-37 129.0 37.4 2.5e-37 128.6 37.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 EEQ34212.1 - 0.019 14.8 2.6 0.019 14.8 2.6 3.3 3 1 1 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Tubulin PF00091.25 EEQ34213.1 - 1.1e-70 237.9 0.0 1.7e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EEQ34213.1 - 8.2e-43 145.6 0.6 1.7e-42 144.5 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EEQ34213.1 - 2.5e-07 31.0 0.0 5.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EEQ34213.1 - 0.032 13.9 0.0 0.082 12.6 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Tubulin_2 PF13809.6 EEQ34213.1 - 0.08 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Hrs_helical PF12210.8 EEQ34213.1 - 0.1 13.2 0.4 0.29 11.7 0.0 1.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DEAD_2 PF06733.15 EEQ34213.1 - 0.2 11.3 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 PfkB PF00294.24 EEQ34214.1 - 0.076 12.3 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Aldo_ket_red PF00248.21 EEQ34215.1 - 1.3e-53 182.1 0.0 1.5e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 EEQ34216.1 - 8.6e-06 26.0 1.3 8.6e-06 26.0 1.3 2.0 3 0 0 3 3 3 1 EamA-like transporter family DUF2892 PF11127.8 EEQ34216.1 - 8.5 6.5 9.3 0.097 12.7 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) Actin PF00022.19 EEQ34217.1 - 1.2e-86 290.9 0.0 8e-86 288.2 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEQ34217.1 - 0.24 10.2 0.0 0.84 8.4 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein DUF3425 PF11905.8 EEQ34218.1 - 4.6e-23 81.5 1.5 7.9e-23 80.8 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) BMFP PF04380.13 EEQ34218.1 - 0.04 14.4 0.4 0.087 13.3 0.4 1.6 1 0 0 1 1 1 0 Membrane fusogenic activity bZIP_1 PF00170.21 EEQ34218.1 - 0.1 12.7 11.3 0.07 13.2 8.2 2.0 1 1 1 2 2 2 0 bZIP transcription factor Zn_clus PF00172.18 EEQ34219.1 - 4.8e-08 33.0 7.6 4.8e-08 33.0 7.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ34219.1 - 9.3e-07 28.1 0.0 1.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 EEQ34220.1 - 1.3e-13 51.1 0.0 1.8e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ34220.1 - 3.6e-13 49.6 0.0 5.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ34220.1 - 9.7e-13 48.6 0.0 1.9e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ34220.1 - 4.1e-12 46.6 0.0 8.6e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ34220.1 - 3.1e-11 43.9 0.0 5.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ34220.1 - 2e-06 27.3 0.0 6.6e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EEQ34220.1 - 0.00024 21.1 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EEQ34220.1 - 0.0065 15.6 0.0 0.032 13.3 0.0 1.9 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 EEQ34220.1 - 0.043 13.4 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_19 PF04672.12 EEQ34220.1 - 0.052 13.0 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase GTP_cyclohydro2 PF00925.20 EEQ34221.1 - 9.5e-59 197.6 0.0 1.3e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF1325 PF07039.11 EEQ34222.1 - 4.3e-35 120.7 0.0 8.2e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 EEQ34222.1 - 0.0069 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain PMI_typeI PF01238.21 EEQ34223.1 - 8.8e-148 492.5 0.0 1e-147 492.2 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Say1_Mug180 PF10340.9 EEQ34224.1 - 1.5e-22 80.0 0.0 2.1e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EEQ34224.1 - 1.7e-21 77.0 0.0 2.7e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ34224.1 - 0.0019 17.7 0.0 0.042 13.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.8 EEQ34224.1 - 0.044 13.3 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Coatomer_E PF04733.14 EEQ34225.1 - 3.5e-61 207.2 8.9 4e-61 207.0 8.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EEQ34225.1 - 2.1e-08 34.5 21.4 0.00032 21.1 2.7 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ34225.1 - 1.4e-06 28.9 21.1 0.0037 17.9 0.2 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ34225.1 - 5.9e-06 26.7 18.8 0.015 16.1 0.0 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ34225.1 - 3.6e-05 23.9 8.0 0.078 13.2 2.1 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EEQ34225.1 - 7.9e-05 23.1 3.0 0.1 13.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ34225.1 - 0.00029 21.0 11.7 0.67 10.3 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF627 PF04781.12 EEQ34225.1 - 0.0061 16.5 1.2 0.016 15.2 1.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF627) TPR_4 PF07721.14 EEQ34225.1 - 0.013 16.1 22.8 0.26 12.0 0.7 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Peptidase_S11 PF00768.20 EEQ34225.1 - 0.022 14.2 0.6 0.032 13.7 0.6 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase NTP_transferase PF00483.23 EEQ34225.1 - 0.065 12.8 0.8 0.11 12.0 0.8 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase TPR_2 PF07719.17 EEQ34225.1 - 0.096 12.8 0.0 0.096 12.8 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ34225.1 - 0.16 11.8 5.6 0.71 9.8 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ34225.1 - 0.25 11.5 0.0 0.25 11.5 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ34225.1 - 1.2 9.2 10.0 16 5.5 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ34225.1 - 3.1 7.6 6.7 2.6 7.8 0.1 3.6 4 0 0 4 4 4 0 TPR repeat Fungal_trans PF04082.18 EEQ34226.1 - 6.6e-07 28.6 0.3 1.1e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cep3 PF16846.5 EEQ34226.1 - 0.074 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B MFS_1 PF07690.16 EEQ34227.1 - 3.5e-35 121.6 77.2 5.7e-28 97.9 44.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ34227.1 - 2.4e-05 23.4 33.4 8e-05 21.7 5.8 3.5 1 1 1 3 3 3 3 Sugar (and other) transporter AA_permease PF00324.21 EEQ34229.1 - 1.7e-124 416.0 38.5 2.1e-124 415.7 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ34229.1 - 2.6e-34 118.8 43.0 3.6e-34 118.3 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM213 PF15192.6 EEQ34229.1 - 0.099 12.6 0.4 0.099 12.6 0.4 1.9 2 0 0 2 2 2 0 TMEM213 family APH PF01636.23 EEQ34230.1 - 8.4e-15 55.3 0.1 9.2e-14 51.9 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EEQ34230.1 - 0.1 11.9 0.0 3.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain FTA4 PF13093.6 EEQ34231.1 - 2.9e-62 210.1 0.2 3.5e-62 209.9 0.2 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spc29 PF17082.5 EEQ34231.1 - 0.0047 16.8 0.9 0.013 15.4 0.8 1.7 1 1 1 2 2 2 1 Spindle Pole Component 29 SlyX PF04102.12 EEQ34232.1 - 0.054 14.1 0.7 0.38 11.4 0.3 2.4 2 0 0 2 2 2 0 SlyX SIKE PF05769.11 EEQ34232.1 - 0.45 10.4 5.4 0.6 10.0 5.4 1.2 1 0 0 1 1 1 0 SIKE family HAD_2 PF13419.6 EEQ34233.1 - 3.4e-06 27.3 0.0 5.4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ34233.1 - 0.00098 19.5 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ34233.1 - 0.013 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Ribosomal_L5e PF17144.4 EEQ34234.1 - 1.8e-80 268.6 0.4 2.7e-80 268.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EEQ34234.1 - 1.7e-33 115.4 5.6 1.7e-33 115.4 5.6 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_6 PF13516.6 EEQ34235.1 - 0.00031 20.6 0.7 14 6.1 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich repeat DUF3135 PF11333.8 EEQ34235.1 - 0.0013 18.9 0.2 0.077 13.3 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3135) ABC_membrane_2 PF06472.15 EEQ34236.1 - 2.6e-96 322.2 0.8 3.6e-96 321.7 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EEQ34236.1 - 2e-18 67.2 0.0 3.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EEQ34236.1 - 4.4e-05 23.5 0.1 0.00017 21.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EEQ34236.1 - 0.0048 17.4 0.1 0.012 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EEQ34236.1 - 0.0092 15.7 0.1 0.041 13.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 EEQ34236.1 - 0.032 13.7 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EEQ34236.1 - 0.055 13.9 0.4 0.42 11.0 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 EEQ34236.1 - 0.073 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EEQ34236.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 EEQ34236.1 - 0.18 11.5 0.1 0.49 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain p450 PF00067.22 EEQ34237.1 - 2.2e-41 142.1 0.3 2.7e-23 82.4 0.0 2.8 2 1 1 3 3 3 3 Cytochrome P450 APH PF01636.23 EEQ34238.1 - 3.1e-13 50.2 0.0 5.1e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EEQ34238.1 - 0.00048 19.6 0.0 0.034 13.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.20 EEQ34238.1 - 0.012 15.2 0.2 0.019 14.6 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EEQ34239.1 - 9.3e-22 78.1 0.0 1.3e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ34239.1 - 3.8e-05 23.4 0.0 6.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Phosphorylase PF00343.20 EEQ34241.1 - 0 1055.5 0.0 0 1055.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.20 EEQ34242.1 - 1.5e-115 386.2 0.6 1.7e-115 386.0 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EEQ34242.1 - 8.9e-16 57.8 1.6 2.8e-10 39.9 0.3 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ34242.1 - 4.2e-05 23.0 0.3 0.064 12.6 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EEQ34242.1 - 0.0038 17.4 0.2 0.81 9.9 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 EEQ34242.1 - 0.016 15.1 0.3 0.033 14.1 0.1 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 EEQ34242.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 EEQ34243.1 - 2.1e-67 227.3 0.0 2.5e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34243.1 - 1.7e-32 112.7 0.0 2.5e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ34243.1 - 1.2e-05 24.4 0.1 1.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEQ34243.1 - 9.8e-05 21.8 0.1 0.00031 20.2 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ34243.1 - 0.0008 19.4 0.0 0.0026 17.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ34243.1 - 0.00087 18.7 0.0 0.025 13.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EEQ34243.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EEQ34243.1 - 0.042 13.4 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.9 EEQ34244.1 - 2.5e-142 474.1 0.0 3.5e-142 473.6 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EEQ34244.1 - 1.8e-08 34.3 3.6 4.5e-06 26.5 0.2 3.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EEQ34244.1 - 6.2e-08 32.6 0.0 0.00048 20.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis BRD4_CDT PF17105.5 EEQ34244.1 - 1.5 8.5 4.8 3.9 7.2 4.8 1.7 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Afi1 PF07792.12 EEQ34244.1 - 1.9 8.9 0.0 1.9 8.9 0.0 2.9 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Cullin PF00888.22 EEQ34245.1 - 6.2e-178 593.3 4.8 9e-178 592.7 4.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EEQ34245.1 - 5.8e-27 93.5 2.7 5.8e-27 93.5 2.7 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain KcnmB2_inactiv PF09303.10 EEQ34246.1 - 0.00032 20.4 0.5 0.0008 19.1 0.5 1.6 1 0 0 1 1 1 1 KCNMB2, ball and chain domain MARVEL PF01284.23 EEQ34246.1 - 0.0024 17.9 2.9 0.0036 17.3 2.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF1418 PF07214.12 EEQ34246.1 - 0.059 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DUF2052 PF09747.9 EEQ34246.1 - 0.068 13.3 1.8 0.099 12.8 1.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Mit_KHE1 PF10173.9 EEQ34247.1 - 8.8e-65 218.4 0.6 1.3e-64 217.8 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related ABC2_membrane_4 PF12730.7 EEQ34247.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein APH PF01636.23 EEQ34248.1 - 5.9e-19 68.9 0.0 3.3e-18 66.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ34248.1 - 3.9e-05 22.7 0.2 0.075 11.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 EEQ34248.1 - 0.00022 20.7 0.0 0.0004 19.8 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 EEQ34248.1 - 0.025 13.8 0.0 0.48 9.6 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase IRF-2BP1_2 PF11261.8 EEQ34248.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Glyco_tran_28_C PF04101.16 EEQ34248.1 - 0.16 11.9 0.0 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain End3 PF12761.7 EEQ34249.1 - 7.8e-73 244.9 2.3 1.1e-72 244.5 2.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EEQ34249.1 - 7e-52 173.8 0.2 1.2e-49 166.5 0.1 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EEQ34249.1 - 8.8e-08 31.2 0.2 2.6e-07 29.7 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EEQ34249.1 - 1.3e-06 28.7 0.6 7.2e-06 26.4 0.1 2.5 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EEQ34249.1 - 9.7e-05 22.0 0.5 0.00043 20.0 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EEQ34249.1 - 0.0016 18.2 0.2 0.0053 16.6 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EEQ34249.1 - 0.0028 17.1 1.0 0.0094 15.4 0.2 2.2 2 0 0 2 2 2 1 EF hand SKA1 PF07160.12 EEQ34249.1 - 0.022 14.6 0.2 0.022 14.6 0.2 1.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 NPV_P10 PF05531.12 EEQ34249.1 - 0.056 13.9 0.6 0.27 11.7 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MDMPI_N PF11716.8 EEQ34249.1 - 0.067 13.9 2.1 0.3 11.8 0.0 2.7 2 1 1 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF4407 PF14362.6 EEQ34249.1 - 0.073 12.4 6.1 0.11 11.9 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med9 PF07544.13 EEQ34249.1 - 0.098 12.8 3.1 0.38 10.9 0.2 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.12 EEQ34249.1 - 0.57 10.2 5.6 0.71 9.9 0.5 2.3 1 1 1 2 2 2 0 Laminin Domain II COG2 PF06148.11 EEQ34249.1 - 0.96 9.5 4.5 2.6 8.2 0.6 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 EEQ34249.1 - 2.3 7.0 11.9 0.25 10.2 4.6 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 EEQ34249.1 - 8.6 7.1 6.1 36 5.1 0.1 2.9 2 1 1 3 3 3 0 SlyX SNF2_N PF00176.23 EEQ34250.1 - 6.4e-49 166.5 0.2 6.6e-48 163.2 0.2 2.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ34250.1 - 1.3e-21 77.0 0.5 1.3e-20 73.7 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EEQ34250.1 - 5.7e-05 22.4 1.0 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 EEQ34250.1 - 0.0007 18.9 6.6 0.019 14.1 0.0 4.1 4 2 0 4 4 4 2 Class II histone deacetylase complex subunits 2 and 3 PDE6_gamma PF04868.12 EEQ34250.1 - 1.5 9.1 7.8 0.63 10.3 0.3 2.6 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit Ribosomal_L5e PF17144.4 EEQ34251.1 - 0.082 12.9 0.1 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Ribosomal large subunit proteins 60S L5, and 50S L18 DSPc PF00782.20 EEQ34252.1 - 1.4e-09 37.9 0.1 2.7e-09 37.0 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EEQ34252.1 - 0.0018 18.5 0.1 0.0032 17.8 0.1 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Peptidase_M15_2 PF05951.13 EEQ34252.1 - 0.054 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Mst1_SARAH PF11629.8 EEQ34252.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 zf-C2H2 PF00096.26 EEQ34253.1 - 4.6e-09 36.2 10.1 0.00047 20.5 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EEQ34253.1 - 6.5e-05 23.1 0.1 0.00011 22.4 0.1 1.3 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EEQ34253.1 - 0.0036 18.0 6.2 6.5 7.9 0.1 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger Transpos_assoc PF13963.6 EEQ34253.1 - 0.097 13.0 0.7 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Transposase-associated domain WD40 PF00400.32 EEQ34255.1 - 9.7e-49 162.3 21.9 4.4e-09 36.8 0.3 8.7 7 2 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ34255.1 - 1.1e-10 41.7 0.0 0.00051 20.3 0.0 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ34255.1 - 1.2e-07 30.8 2.2 0.0019 16.9 0.1 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EEQ34255.1 - 2.1e-05 23.5 0.1 0.016 14.0 0.0 3.3 2 1 1 3 3 3 2 Nup133 N terminal like Pox_A_type_inc PF04508.12 EEQ34255.1 - 0.083 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF4094 PF13334.6 EEQ34255.1 - 0.17 12.3 0.9 0.39 11.2 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) p450 PF00067.22 EEQ34256.1 - 1.5e-73 248.2 0.0 1.7e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 A_deaminase PF00962.22 EEQ34257.1 - 5.2e-26 91.8 0.0 6.5e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Urb2 PF10441.9 EEQ34258.1 - 1.1e-62 211.6 0.8 2.4e-62 210.5 0.1 2.0 2 0 0 2 2 2 1 Urb2/Npa2 family DUF543 PF04418.12 EEQ34259.1 - 6.5e-28 96.5 0.0 8e-28 96.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Metallothio_2 PF01439.18 EEQ34260.1 - 0.7 10.8 26.0 0.094 13.6 6.8 3.8 4 0 0 4 4 4 0 Metallothionein GST_N_4 PF17172.4 EEQ34261.1 - 6e-23 81.5 0.0 1.9e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EEQ34261.1 - 2.3e-19 68.9 0.3 5.3e-19 67.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EEQ34261.1 - 3.1e-13 50.1 0.0 6.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 EEQ34261.1 - 4e-06 27.1 0.1 9.5e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 EEQ34261.1 - 0.048 13.7 0.2 0.091 12.8 0.2 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.6 EEQ34262.1 - 8e-17 61.7 0.0 1.6e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ34262.1 - 1.1e-16 61.2 0.0 2.3e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ34262.1 - 5.1e-14 52.3 0.0 8.2e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ34262.1 - 3.5e-13 50.1 0.0 7.4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ34262.1 - 7.9e-12 45.3 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ34262.1 - 1.7e-07 30.8 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EEQ34262.1 - 2e-06 27.5 0.0 7.7e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.26 EEQ34262.1 - 6.1e-06 26.2 0.1 0.00093 19.2 0.1 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase CMAS PF02353.20 EEQ34262.1 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EEQ34262.1 - 0.00038 20.0 0.0 0.0011 18.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 EEQ34262.1 - 0.00056 19.4 0.0 0.00096 18.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 EEQ34262.1 - 0.00092 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EEQ34262.1 - 0.0013 18.1 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EEQ34262.1 - 0.003 17.6 0.0 0.0058 16.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EEQ34262.1 - 0.011 15.2 0.0 0.34 10.4 0.0 2.1 1 1 1 2 2 2 0 MraW methylase family Pox_MCEL PF03291.16 EEQ34262.1 - 0.031 13.4 0.0 0.92 8.6 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme NodS PF05401.11 EEQ34262.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DOT1 PF08123.13 EEQ34262.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 EEQ34262.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_7 PF03492.15 EEQ34262.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase GidB PF02527.15 EEQ34262.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G CDC14 PF08045.11 EEQ34263.1 - 3.8e-130 433.1 0.0 4.2e-130 432.9 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Sugar_tr PF00083.24 EEQ34266.1 - 7.6e-85 285.4 19.9 8.9e-85 285.2 19.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ34266.1 - 1.4e-13 50.5 42.2 2.4e-12 46.5 35.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_4 PF01063.19 EEQ34267.1 - 8.4e-23 81.4 0.0 1e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Cyclin PF08613.11 EEQ34268.1 - 9.2e-06 26.1 0.0 9.2e-06 26.1 0.0 3.1 4 0 0 4 4 4 1 Cyclin Cyclin_N PF00134.23 EEQ34268.1 - 0.0031 17.3 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cation_efflux PF01545.21 EEQ34269.1 - 6.3e-28 97.9 12.9 3.7e-27 95.4 12.9 2.0 1 1 0 1 1 1 1 Cation efflux family EphA2_TM PF14575.6 EEQ34269.1 - 0.15 12.9 0.5 3.4 8.6 0.0 2.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Epiglycanin_C PF14654.6 EEQ34269.1 - 0.17 12.0 2.3 0.37 10.9 2.3 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Aldedh PF00171.22 EEQ34270.1 - 7.5e-144 479.7 0.0 9e-144 479.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LysM PF01476.20 EEQ34272.1 - 4.4e-12 45.9 0.0 2.2e-05 24.4 0.0 2.9 3 0 0 3 3 3 2 LysM domain Cytochrom_B558a PF05038.13 EEQ34272.1 - 0.063 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit CybS PF05328.12 EEQ34272.1 - 0.072 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit Macoilin PF09726.9 EEQ34273.1 - 2.7 6.5 5.9 4.3 5.8 5.9 1.4 1 0 0 1 1 1 0 Macoilin family Ribosomal_S13 PF00416.22 EEQ34274.1 - 6.1e-56 188.3 4.0 7e-56 188.1 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EEQ34274.1 - 0.015 14.0 0.1 0.021 13.6 0.0 1.2 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 EEQ34274.1 - 0.046 14.0 0.1 0.22 11.8 0.0 2.1 1 1 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_S10 PF00450.22 EEQ34275.1 - 2.2e-130 435.8 0.1 2.9e-130 435.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EEQ34275.1 - 7.2e-05 23.3 2.0 0.00063 20.3 2.0 2.3 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide LtuB PF17455.2 EEQ34275.1 - 0.054 14.1 0.0 0.19 12.4 0.0 1.9 2 0 0 2 2 2 0 Late transcription unit B SBDS_C PF09377.10 EEQ34276.1 - 6.7e-43 145.4 0.0 9.5e-43 144.9 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EEQ34276.1 - 4.8e-28 97.1 0.0 9e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein AP3D1 PF06375.11 EEQ34276.1 - 0.022 15.0 3.6 0.041 14.1 0.2 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Presenilin PF01080.17 EEQ34276.1 - 0.083 11.6 1.0 0.12 11.1 1.0 1.2 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 EEQ34276.1 - 0.68 9.6 5.7 12 5.5 0.3 3.0 3 0 0 3 3 3 0 FAM176 family FGF-BP1 PF06473.12 EEQ34276.1 - 1.4 8.7 6.4 1.9 8.2 0.6 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) TFIIE-A_C PF11521.8 EEQ34276.1 - 2.9 8.3 10.0 6 7.2 1.5 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Coilin_N PF15862.5 EEQ34276.1 - 4.4 7.1 7.1 1 9.2 0.3 2.2 2 0 0 2 2 2 0 Coilin N-terminus RseA_N PF03872.13 EEQ34277.1 - 0.0092 16.4 1.9 0.08 13.4 0.1 2.3 2 0 0 2 2 2 1 Anti sigma-E protein RseA, N-terminal domain MCU PF04678.13 EEQ34277.1 - 0.41 10.7 2.3 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF3043 PF11241.8 EEQ34278.1 - 0.6 10.1 9.2 2.6 8.1 9.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Pyridoxal_deC PF00282.19 EEQ34279.1 - 7.9e-79 265.1 0.0 1e-78 264.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EEQ34279.1 - 0.00021 20.4 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EEQ34279.1 - 0.032 13.0 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 EEQ34279.1 - 0.046 13.0 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans_2 PF11951.8 EEQ34280.1 - 5.6e-07 28.7 1.0 9e-07 28.0 0.9 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ34280.1 - 1.2e-06 28.6 11.6 2.5e-06 27.5 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UL73_N PF12522.8 EEQ34280.1 - 9 6.1 10.3 25 4.7 10.3 1.7 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal COesterase PF00135.28 EEQ34281.1 - 7.5e-61 206.6 0.0 8.6e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EEQ34281.1 - 0.00091 19.1 0.2 0.0064 16.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ34281.1 - 0.12 11.9 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family peroxidase PF00141.23 EEQ34283.1 - 6.6e-46 156.8 0.0 9.3e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.6 EEQ34283.1 - 0.16 11.3 0.0 0.34 10.3 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) Spidroin_N PF16763.5 EEQ34284.1 - 0.62 10.1 6.9 2.9 7.9 0.5 2.1 1 1 1 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term TPR_2 PF07719.17 EEQ34285.1 - 0.017 15.2 6.6 0.66 10.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ34285.1 - 0.08 12.8 10.7 0.18 11.7 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ34285.1 - 0.31 11.6 5.0 0.11 13.0 1.3 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.18 EEQ34286.1 - 7.5e-06 26.0 10.3 1.6e-05 24.9 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 EEQ34287.1 - 8.5e-45 153.3 0.0 1.1e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SSXT PF05030.12 EEQ34290.1 - 0.00025 20.6 0.0 0.0099 15.5 0.0 3.2 4 0 0 4 4 4 2 SSXT protein (N-terminal region) PDZ_1 PF12812.7 EEQ34291.1 - 8.8e-53 176.3 0.0 1.5e-34 117.8 0.0 3.1 3 0 0 3 3 3 2 PDZ-like domain PDZ_6 PF17820.1 EEQ34291.1 - 1.1e-14 53.9 0.7 4.6e-05 23.2 0.4 4.7 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.6 EEQ34291.1 - 3.6e-14 53.9 0.2 5.8e-13 50.0 0.0 2.4 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 EEQ34291.1 - 5e-13 49.2 0.0 0.00027 21.2 0.0 4.2 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 EEQ34291.1 - 2e-08 34.5 0.0 0.00052 20.3 0.0 3.6 3 0 0 3 3 3 1 PDZ domain Tricorn_PDZ PF14685.6 EEQ34291.1 - 0.00075 19.4 0.1 3.8 7.6 0.1 4.1 4 0 0 4 4 4 1 Tricorn protease PDZ domain Trypsin PF00089.26 EEQ34291.1 - 0.03 14.2 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Trypsin 4HPAD_g_N PF18671.1 EEQ34291.1 - 0.066 12.9 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal DUF31 PF01732.16 EEQ34291.1 - 0.15 11.6 0.3 0.22 11.0 0.3 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 EEQ34291.1 - 0.21 10.2 0.1 0.33 9.6 0.1 1.1 1 0 0 1 1 1 0 Peptidase S46 INCENP_ARK-bind PF03941.15 EEQ34292.1 - 2.7e-16 59.2 0.9 2.7e-16 59.2 0.9 2.3 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region FAM199X PF15814.5 EEQ34292.1 - 0.21 10.6 26.4 1.2 8.2 3.7 2.5 2 0 0 2 2 2 0 Protein family FAM199X DNA_topoisoIV PF00521.20 EEQ34293.1 - 1.4e-133 445.9 0.3 3e-133 444.8 0.1 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EEQ34293.1 - 3.5e-52 176.0 7.5 3.5e-52 176.0 7.5 2.2 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EEQ34293.1 - 1.9e-27 95.9 2.2 6.5e-27 94.1 2.2 1.9 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EEQ34293.1 - 9.5e-15 55.1 0.0 3.3e-14 53.3 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EEQ34293.1 - 5.6e-07 29.7 0.0 3.6e-06 27.1 0.0 2.5 1 0 0 1 1 1 1 Toprim domain Reticulon PF02453.17 EEQ34295.1 - 6.1e-26 91.3 4.5 1e-25 90.5 4.5 1.3 1 0 0 1 1 1 1 Reticulon Tmemb_185A PF10269.9 EEQ34295.1 - 0.0059 16.3 0.7 0.0086 15.8 0.7 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein CDC27 PF09507.10 EEQ34295.1 - 0.028 13.8 4.0 0.034 13.5 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Met_asp_mut_E PF06368.11 EEQ34295.1 - 0.069 11.6 0.4 0.089 11.2 0.4 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) PP2C_C PF07830.13 EEQ34295.1 - 0.97 9.9 5.7 0.21 12.1 2.1 1.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Pex24p PF06398.11 EEQ34295.1 - 1.6 7.6 5.6 4.5 6.2 0.8 2.0 1 1 0 2 2 2 0 Integral peroxisomal membrane peroxin CCDC53 PF10152.9 EEQ34295.1 - 5.7 7.4 9.2 13 6.1 9.2 1.5 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Acyl-CoA_dh_1 PF00441.24 EEQ34296.1 - 7.2e-26 91.2 2.4 1.2e-25 90.4 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EEQ34296.1 - 6.9e-20 71.8 0.3 5.7e-11 43.1 0.1 2.6 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EEQ34296.1 - 2.4e-13 50.5 0.7 4.8e-13 49.5 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EEQ34296.1 - 2.9e-07 30.6 0.0 5.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain RabGAP-TBC PF00566.18 EEQ34297.1 - 2.5e-49 167.9 0.1 3.5e-48 164.1 0.0 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EzrA PF06160.12 EEQ34297.1 - 1.7 6.7 16.4 0.7 8.0 0.1 3.0 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA ADIP PF11559.8 EEQ34297.1 - 3 7.9 28.3 0.41 10.7 11.5 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 EEQ34297.1 - 5.3 7.1 14.2 0.057 13.5 3.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) USP8_interact PF08941.10 EEQ34297.1 - 7.9 6.2 9.4 0.59 9.9 0.8 2.9 3 0 0 3 3 3 0 USP8 interacting MFS_1 PF07690.16 EEQ34298.1 - 2.2e-27 95.9 37.1 6.8e-27 94.3 35.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ34298.1 - 0.00042 18.9 1.8 0.00054 18.5 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Med4 PF10018.9 EEQ34299.1 - 1.9e-34 119.1 1.7 5.8e-34 117.5 1.7 1.8 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Rac1 PF09632.10 EEQ34299.1 - 0.032 13.4 1.2 0.049 12.8 0.3 1.7 2 0 0 2 2 2 0 Rac1-binding domain EF-hand_1 PF00036.32 EEQ34300.1 - 2.3e-26 89.3 9.6 2.7e-08 32.8 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EEQ34300.1 - 1.5e-25 86.9 2.7 3e-06 26.7 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 EEQ34300.1 - 1.7e-24 86.0 6.0 8.6e-16 58.2 0.6 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EEQ34300.1 - 1.1e-17 62.6 14.6 1.9e-05 24.0 0.0 4.8 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 EEQ34300.1 - 3.2e-16 58.9 9.9 3.2e-06 26.9 0.9 4.2 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EEQ34300.1 - 4.2e-09 36.3 4.6 0.001 19.0 0.1 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EEQ34300.1 - 8.7e-05 22.8 0.4 0.14 12.5 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EEQ34300.1 - 0.0033 17.7 0.9 0.52 10.7 0.2 3.1 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 EEQ34300.1 - 0.016 14.1 0.5 1.2 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 EEQ34300.1 - 0.033 14.1 2.3 1.3 9.0 0.1 3.6 4 1 0 4 4 4 0 EF hand EMP70 PF02990.16 EEQ34301.1 - 1.1e-194 648.0 5.4 1.4e-194 647.6 5.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 FmrO PF07091.11 EEQ34302.1 - 0.085 12.4 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) FKBP_C PF00254.28 EEQ34303.1 - 1.2e-06 28.7 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF953 PF06110.11 EEQ34303.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) zf-C2H2_jaz PF12171.8 EEQ34303.1 - 0.34 11.3 6.6 3.9 7.9 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EEQ34303.1 - 1.2 9.9 5.1 1.4 9.6 0.3 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EEQ34303.1 - 2 9.5 9.0 8.3 7.6 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Trm5_N PF18093.1 EEQ34304.1 - 0.19 11.6 0.2 0.39 10.6 0.2 1.5 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain DUF2112 PF09885.9 EEQ34305.1 - 0.063 13.3 0.0 1.4 8.9 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2112) FMO-like PF00743.19 EEQ34310.1 - 2.3e-15 56.0 0.0 9.2e-15 54.0 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EEQ34310.1 - 5.9e-14 52.0 0.0 5.9e-11 42.2 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ34310.1 - 4.7e-13 49.0 0.0 2.4e-12 46.7 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ34310.1 - 1e-10 41.3 0.0 1.2e-08 34.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EEQ34310.1 - 4.1e-07 30.1 0.6 1.6e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ34310.1 - 2.7e-06 27.8 4.6 0.0093 16.5 0.1 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EEQ34310.1 - 2.8e-06 26.8 0.3 0.008 15.5 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EEQ34310.1 - 6.2e-05 22.7 0.7 0.016 14.8 0.2 3.2 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EEQ34310.1 - 0.00035 20.6 2.1 0.052 13.5 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EEQ34310.1 - 0.0038 17.6 0.0 0.068 13.6 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 EEQ34310.1 - 0.0079 16.1 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EEQ34310.1 - 0.033 13.3 0.2 0.033 13.3 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 EEQ34310.1 - 0.043 13.9 0.1 4.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 EEQ34310.1 - 0.14 11.4 0.7 0.67 9.2 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EEQ34310.1 - 0.16 10.7 2.2 2.5 6.7 0.2 2.8 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 EEQ34310.1 - 0.2 11.0 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 EEQ34310.1 - 0.21 10.8 0.0 3.9 6.6 0.0 2.1 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EEQ34310.1 - 0.24 10.6 0.1 0.39 9.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EEQ34310.1 - 4 6.4 4.4 1.5 7.8 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Sas10_Utp3 PF04000.15 EEQ34312.1 - 3.1e-17 63.0 0.8 3.1e-17 63.0 0.8 2.3 2 1 0 2 2 2 1 Sas10/Utp3/C1D family PBP_sp32 PF07222.12 EEQ34312.1 - 6.8 6.1 8.5 2.3 7.6 5.0 2.0 2 1 0 2 2 2 0 Proacrosin binding protein sp32 MFS_1 PF07690.16 EEQ34313.1 - 2.7e-12 46.3 36.5 3.8e-12 45.8 35.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EEQ34313.1 - 7.3e-08 32.3 6.3 7.3e-08 32.3 6.3 3.1 5 1 1 6 6 6 1 Ion channel regulatory protein UNC-93 CFEM PF05730.11 EEQ34314.1 - 1.2e-12 47.7 3.1 1.9e-12 47.1 3.1 1.3 1 0 0 1 1 1 1 CFEM domain UQ_con PF00179.26 EEQ34315.1 - 1.5e-39 134.8 0.0 1.7e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pox_A14 PF05767.12 EEQ34316.1 - 2.1 8.5 7.9 6.4 7.0 0.4 3.0 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 DUF872 PF05915.12 EEQ34316.1 - 3.8 7.7 6.7 1.6 8.9 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) AA_permease PF00324.21 EEQ34317.1 - 2.7e-32 112.0 6.9 2.2e-31 109.0 6.9 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ34317.1 - 2.5e-11 43.0 1.7 3.9e-11 42.4 1.6 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ34318.1 - 3.5e-22 78.7 8.9 4.1e-22 78.4 8.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ34318.1 - 6.6e-10 38.4 7.9 7.9e-10 38.1 7.9 1.0 1 0 0 1 1 1 1 Amino acid permease LtrA PF06772.11 EEQ34321.1 - 5.8e-14 52.1 40.5 7.6e-13 48.4 22.4 3.3 2 1 1 3 3 3 3 Bacterial low temperature requirement A protein (LtrA) DUF2976 PF11190.8 EEQ34321.1 - 1.3 8.9 12.5 0.15 11.9 0.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Mito_carr PF00153.27 EEQ34322.1 - 9e-59 195.4 3.0 3e-19 68.7 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIIC_delta PF12657.7 EEQ34323.1 - 8.1e-46 156.3 1.3 2.2e-45 154.9 1.3 1.8 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EEQ34323.1 - 4.2e-08 33.1 0.1 9.4e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex MFS_1 PF07690.16 EEQ34324.1 - 2.6e-34 118.7 40.8 2.6e-34 118.7 40.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ34324.1 - 1.5e-15 56.7 22.2 2e-15 56.3 22.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ34324.1 - 1.7e-11 43.6 8.4 1.7e-11 43.6 8.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter PS-DH PF14765.6 EEQ34325.1 - 7.5e-66 222.4 0.1 1.1e-65 221.8 0.1 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EEQ34325.1 - 3.2e-10 40.0 0.0 6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EEQ34325.1 - 5.8e-10 39.2 0.0 3.1e-09 36.8 0.0 2.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Glyco_trans_1_4 PF13692.6 EEQ34326.1 - 2.1e-06 28.2 0.0 2.1e-05 24.9 0.0 2.4 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EEQ34326.1 - 3.9e-06 27.4 3.4 6.8e-06 26.6 3.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 EEQ34326.1 - 0.00013 21.6 0.0 0.0009 18.8 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EEQ34326.1 - 0.00014 22.2 0.0 0.00028 21.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEQ34326.1 - 0.0056 16.7 2.6 0.0095 15.9 2.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Cation_efflux PF01545.21 EEQ34327.1 - 2.8e-46 157.8 15.5 2.8e-46 157.8 15.5 2.3 3 0 0 3 3 3 1 Cation efflux family UQ_con PF00179.26 EEQ34328.1 - 1.3e-51 173.9 0.0 1.5e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ34328.1 - 0.0007 19.3 0.0 0.00078 19.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EEQ34328.1 - 0.083 13.2 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.23 EEQ34329.1 - 1.1e-91 306.8 1.1 1.5e-91 306.4 1.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EEQ34329.1 - 1.3e-37 128.2 0.6 1.3e-37 128.2 0.6 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EEQ34329.1 - 6.1e-05 22.7 0.2 0.00015 21.4 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EEQ34329.1 - 0.016 15.1 2.8 2.4 8.0 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Kinesin PF00225.23 EEQ34330.1 - 2e-112 375.4 0.4 5.4e-112 374.0 0.4 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ34330.1 - 3.8e-26 91.8 0.1 1.6e-25 89.8 0.1 2.1 1 0 0 1 1 1 1 Microtubule binding DUF1398 PF07166.11 EEQ34330.1 - 0.062 13.4 0.2 0.2 11.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) POTRA_2 PF08479.11 EEQ34330.1 - 0.12 12.2 0.3 3.6 7.5 0.0 2.9 2 0 0 2 2 2 0 POTRA domain, ShlB-type Nbl1_Borealin_N PF10444.9 EEQ34330.1 - 0.74 9.5 9.5 0.57 9.9 0.6 4.5 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal HAP1_N PF04849.13 EEQ34330.1 - 1.8 7.7 48.3 0.017 14.3 16.8 4.1 2 1 1 3 3 3 0 HAP1 N-terminal conserved region ERM PF00769.19 EEQ34330.1 - 2.7 7.7 58.0 0.33 10.7 9.8 4.2 3 1 1 4 4 4 0 Ezrin/radixin/moesin family DUF2048 PF09752.9 EEQ34330.1 - 6.5 5.7 6.8 0.23 10.5 0.3 1.8 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Peptidase_C1_2 PF03051.15 EEQ34331.1 - 2.1e-161 537.6 0.0 2.4e-161 537.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EEQ34331.1 - 9.4e-10 38.9 0.1 5e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 Papain family cysteine protease UPF0160 PF03690.13 EEQ34332.1 - 3.1e-122 408.2 0.0 3.5e-122 408.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Rib PF08428.10 EEQ34332.1 - 0.16 12.0 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Rib/alpha-like repeat 5_nucleotid_C PF02872.18 EEQ34333.1 - 2.6e-37 128.5 0.0 7e-37 127.1 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EEQ34333.1 - 2.3e-05 25.0 0.0 4.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 EEQ34334.1 - 7.6e-06 25.5 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EEQ34334.1 - 0.00029 20.3 0.1 0.00065 19.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ34334.1 - 0.00037 20.5 0.0 0.00037 20.5 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Lzipper-MIP1 PF14389.6 EEQ34334.1 - 0.055 13.8 1.0 0.16 12.3 1.0 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_trans_1_2 PF13524.6 EEQ34334.1 - 0.1 13.0 3.1 0.11 13.0 1.2 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 RIO1 PF01163.22 EEQ34334.1 - 0.19 11.3 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Peptidase_M35 PF02102.15 EEQ34336.1 - 9.5e-94 314.2 10.4 1.5e-93 313.6 10.4 1.3 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EEQ34336.1 - 4.1e-45 153.9 3.2 8.5e-45 152.9 3.2 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EEQ34336.1 - 2.1e-05 24.2 3.8 0.00022 20.9 3.8 2.0 1 1 0 1 1 1 1 Putative peptidase family His_Phos_1 PF00300.22 EEQ34337.1 - 0.00077 19.2 3.8 10 5.7 0.6 4.1 3 1 1 4 4 4 4 Histidine phosphatase superfamily (branch 1) CorA PF01544.18 EEQ34338.1 - 0.003 16.9 0.4 0.004 16.5 0.4 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Rib_hydrolayse PF02267.17 EEQ34341.1 - 0.032 13.7 0.0 0.041 13.3 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosyl cyclase Ank_2 PF12796.7 EEQ34342.1 - 1.2e-15 57.8 0.4 2.3e-07 31.3 0.0 3.3 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ34342.1 - 3.9e-15 56.0 0.1 7.2e-05 23.3 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ34342.1 - 3.1e-14 52.9 4.6 0.0004 20.6 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ34342.1 - 1.6e-12 46.4 2.1 0.0022 18.3 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EEQ34342.1 - 4.8e-08 33.1 3.8 0.0041 17.5 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat DUF1843 PF08898.10 EEQ34342.1 - 0.048 14.2 0.0 1.6 9.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) TPR_12 PF13424.6 EEQ34343.1 - 5.6e-18 65.0 3.0 1.3e-06 28.5 0.7 5.2 3 1 3 6 6 6 5 Tetratricopeptide repeat NB-ARC PF00931.22 EEQ34343.1 - 6.3e-09 35.4 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 EEQ34343.1 - 1.9e-06 27.6 0.3 0.00095 19.0 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ34343.1 - 6.9e-06 25.8 7.2 0.1 12.7 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ34343.1 - 0.00019 21.1 4.2 0.34 10.8 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.6 EEQ34343.1 - 0.0029 17.9 0.0 0.044 14.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain TPR_8 PF13181.6 EEQ34343.1 - 0.0046 17.1 0.9 60 4.2 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF676 PF05057.14 EEQ34343.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_16 PF13191.6 EEQ34343.1 - 0.013 15.9 0.3 0.058 13.8 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Ser_hydrolase PF06821.13 EEQ34343.1 - 0.12 12.3 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF1771 PF08590.10 EEQ34343.1 - 0.14 12.5 0.8 37 4.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) TPR_11 PF13414.6 EEQ34343.1 - 0.15 11.8 0.6 23 4.8 0.0 4.1 5 0 0 5 5 5 0 TPR repeat TPR_16 PF13432.6 EEQ34343.1 - 0.35 11.5 3.9 1.2e+02 3.4 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat CorA PF01544.18 EEQ34344.1 - 5.3e-09 35.8 1.4 9.7e-09 35.0 1.4 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Amidase PF01425.21 EEQ34345.1 - 3.7e-23 82.2 0.0 5.2e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Amidase ECSCR PF15820.5 EEQ34349.1 - 0.7 9.8 8.4 5.5 6.9 0.1 3.2 2 1 1 3 3 3 0 Endothelial cell-specific chemotaxis regulator Ribosomal_S13 PF00416.22 EEQ34350.1 - 5.8e-17 62.3 0.3 7.1e-15 55.5 0.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 WD40 PF00400.32 EEQ34351.1 - 1.8e-18 66.5 19.0 2e-07 31.6 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 EEQ34351.1 - 1.9e-17 63.6 0.1 3.8e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EEQ34351.1 - 0.0071 15.1 0.9 0.2 10.3 0.8 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 ALAD PF00490.21 EEQ34353.1 - 2.8e-104 348.7 0.0 3.2e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Methyltransf_12 PF08242.12 EEQ34354.1 - 7.8e-05 23.4 0.0 0.0002 22.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ34354.1 - 0.00024 20.9 0.0 0.0012 18.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ34354.1 - 0.00029 21.5 0.0 0.0007 20.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ34354.1 - 0.0003 20.6 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ34354.1 - 0.0006 20.4 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding PF00501.28 EEQ34355.1 - 5.5e-73 246.0 0.0 6.6e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ34355.1 - 0.00053 20.9 0.0 0.0014 19.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zw10 PF06248.13 EEQ34356.1 - 7.2e-12 44.7 1.3 4.3e-11 42.1 1.3 2.2 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EEQ34356.1 - 8.1e-06 25.7 0.1 1.8e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Peptidase_M16_C PF05193.21 EEQ34357.1 - 2.1e-15 57.2 0.0 2.5e-13 50.4 0.0 3.1 3 1 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EEQ34357.1 - 0.00015 21.8 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) TFIIA PF03153.13 EEQ34357.1 - 0.75 9.7 19.8 1.2 9.0 19.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vfa1 PF08432.10 EEQ34357.1 - 0.9 9.8 10.1 0.38 11.1 7.1 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.13 EEQ34357.1 - 1.7 8.5 17.9 5.1 6.9 17.9 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region Ank_2 PF12796.7 EEQ34358.1 - 3.7e-37 126.8 0.0 1.7e-11 44.5 0.0 5.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ34358.1 - 4.3e-33 113.3 0.2 2.2e-07 31.3 0.0 7.5 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ34358.1 - 4.9e-22 75.6 0.0 0.021 15.3 0.0 10.3 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 EEQ34358.1 - 4.8e-17 61.6 1.7 0.015 15.8 0.0 8.1 7 2 2 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 EEQ34358.1 - 1.9e-16 59.9 2.9 0.00053 20.2 0.0 7.5 5 2 4 9 9 9 4 Ankyrin repeats (many copies) NACHT PF05729.12 EEQ34358.1 - 0.032 14.1 0.0 0.095 12.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Peptidase_M48_N PF16491.5 EEQ34359.1 - 2.5e-65 219.8 8.3 2.5e-65 219.8 8.3 1.6 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EEQ34359.1 - 3.8e-45 154.1 0.5 5.5e-45 153.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 EEQ34359.1 - 0.0068 15.6 0.5 0.033 13.4 0.2 2.0 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.6 EEQ34359.1 - 0.011 15.5 1.1 0.03 14.1 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Ribosomal_L34 PF00468.17 EEQ34361.1 - 1e-15 57.4 10.2 1.7e-15 56.7 10.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 eIF2_C PF09173.11 EEQ34362.1 - 4.6e-34 116.5 0.2 1.1e-33 115.3 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EEQ34362.1 - 6.2e-23 81.3 0.2 4.3e-22 78.6 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EEQ34362.1 - 8.6e-12 45.3 0.2 1.9e-11 44.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ34362.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ34362.1 - 0.0059 16.5 0.1 0.063 13.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase WD40 PF00400.32 EEQ34363.1 - 6.4e-10 39.5 0.0 0.82 10.6 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EEQ34363.1 - 0.007 15.2 0.0 2.5 6.8 0.0 2.6 2 1 0 3 3 3 2 Nup133 N terminal like CW_7 PF08230.11 EEQ34363.1 - 0.017 14.9 0.2 0.035 13.9 0.2 1.4 1 0 0 1 1 1 0 CW_7 repeat Myb_DNA-bind_6 PF13921.6 EEQ34364.1 - 3.6e-16 59.2 0.1 3.6e-16 59.2 0.1 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain HSA PF07529.13 EEQ34364.1 - 2e-12 47.3 0.8 2e-12 47.3 0.8 3.3 3 0 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 EEQ34364.1 - 0.001 19.2 0.4 0.0029 17.7 0.4 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EEQ34364.1 - 0.083 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Condensation PF00668.20 EEQ34365.1 - 2.6e-27 95.6 6.1 3.3e-15 55.7 0.4 3.1 2 1 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 EEQ34365.1 - 5.2e-26 91.2 0.2 1.7e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 EEQ34365.1 - 4.5e-08 33.3 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ABC_tran PF00005.27 EEQ34366.1 - 1.6e-46 158.2 0.0 7.2e-27 94.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ34366.1 - 3.5e-28 99.0 16.5 3.5e-28 99.0 16.5 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 EEQ34366.1 - 2e-16 60.7 1.7 4.6e-05 23.4 0.0 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ34366.1 - 8.6e-12 45.0 1.2 4.3e-05 23.1 0.1 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ34366.1 - 8.9e-06 25.4 0.3 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ34366.1 - 0.00012 22.3 0.3 0.67 10.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEQ34366.1 - 0.00013 22.4 0.3 0.86 10.0 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ34366.1 - 0.00024 21.1 0.4 0.86 9.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EEQ34366.1 - 0.00033 20.7 0.1 0.83 9.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_ATPase PF09818.9 EEQ34366.1 - 0.0044 15.9 1.1 0.31 9.8 0.1 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.6 EEQ34366.1 - 0.0057 17.2 0.5 5.1 7.7 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EEQ34366.1 - 0.018 15.6 0.3 6.8 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EEQ34366.1 - 0.021 14.1 0.0 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EEQ34366.1 - 0.028 14.3 0.2 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 NTPase DUF389 PF04087.14 EEQ34366.1 - 0.042 13.9 3.9 0.043 13.8 1.0 2.7 2 0 0 2 2 1 0 Domain of unknown function (DUF389) AAA_33 PF13671.6 EEQ34366.1 - 0.047 13.8 0.5 3.3 7.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EEQ34366.1 - 0.049 13.7 1.8 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family T2SSE PF00437.20 EEQ34366.1 - 0.05 12.7 0.1 0.57 9.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 EEQ34366.1 - 0.055 13.2 0.4 8.1 6.0 0.1 2.6 2 1 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.17 EEQ34366.1 - 0.1 12.4 0.6 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 EEQ34366.1 - 0.16 11.0 0.2 0.5 9.3 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB COX2-transmemb PF09125.10 EEQ34366.1 - 0.35 10.7 2.1 1.2 8.9 2.1 2.0 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane AAA_5 PF07728.14 EEQ34366.1 - 0.71 9.9 2.6 8.3 6.4 0.8 3.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) SNF2_N PF00176.23 EEQ34367.1 - 9.3e-07 27.9 0.0 5.3e-06 25.4 0.0 2.1 1 1 1 2 2 2 1 SNF2 family N-terminal domain DNA_pol_phi PF04931.13 EEQ34367.1 - 0.17 10.0 6.2 0.33 9.0 6.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi Helicase_C PF00271.31 EEQ34367.1 - 0.2 12.0 0.1 1.2 9.5 0.0 2.3 2 1 1 3 3 3 0 Helicase conserved C-terminal domain RNase_H2_suC PF08615.11 EEQ34367.1 - 0.21 11.7 2.3 0.45 10.7 2.3 1.5 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TFB6 PF17110.5 EEQ34367.1 - 3.9 7.2 6.1 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 EEQ34367.1 - 5.2 6.7 8.0 7.8 6.2 7.0 1.7 1 1 0 1 1 1 0 FAM176 family G-patch_2 PF12656.7 EEQ34368.1 - 1.9e-23 82.3 0.1 8.5e-23 80.2 0.1 2.3 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 EEQ34368.1 - 0.00045 20.0 0.5 0.0015 18.4 0.5 1.9 1 0 0 1 1 1 1 G-patch domain WD40 PF00400.32 EEQ34369.1 - 2.3e-54 180.2 17.7 1.3e-05 25.8 0.0 13.5 13 2 0 13 13 13 11 WD domain, G-beta repeat Utp13 PF08625.11 EEQ34369.1 - 1.9e-47 160.7 0.1 3e-47 160.1 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EEQ34369.1 - 4.7e-13 49.2 0.5 6.2 7.2 0.0 8.3 7 1 0 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ34369.1 - 7e-07 28.3 7.9 0.041 12.5 0.5 5.1 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ34369.1 - 0.00037 19.6 1.5 3.3 6.6 0.0 5.2 3 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EEQ34369.1 - 0.026 13.3 3.5 5.1 5.7 0.1 4.2 4 2 2 6 6 6 0 Nup133 N terminal like EMP70 PF02990.16 EEQ34369.1 - 0.21 10.2 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 UCH PF00443.29 EEQ34371.1 - 9.9e-23 80.9 0.2 2.8e-22 79.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EEQ34371.1 - 4.5e-12 46.1 0.3 7.8e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EEQ34371.1 - 0.0036 17.0 0.3 0.015 14.9 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TLD PF07534.16 EEQ34372.1 - 1.1e-09 38.6 0.2 1.9e-09 37.8 0.2 1.4 1 0 0 1 1 1 1 TLD MF_alpha_N PF05436.11 EEQ34373.1 - 0.058 13.3 0.6 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus LRRC37AB_C PF14914.6 EEQ34373.1 - 0.68 9.8 2.8 1.4 8.8 2.8 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Proteasome PF00227.26 EEQ34374.1 - 6.8e-30 104.0 0.0 8.3e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 EEQ34375.1 - 2e-17 63.2 15.2 1.1e-05 26.0 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 EEQ34375.1 - 0.00058 18.6 4.3 2.1 6.9 0.1 3.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EEQ34375.1 - 0.0015 18.8 0.0 0.016 15.5 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EEQ34375.1 - 0.0089 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain zf-C3HC4_3 PF13920.6 EEQ34376.1 - 8.2e-09 35.2 5.1 8.2e-09 35.2 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ34376.1 - 8.5e-09 35.6 7.5 8.5e-09 35.6 7.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EEQ34376.1 - 1.4e-08 34.4 7.4 1.4e-08 34.4 7.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ34376.1 - 2e-08 33.9 7.9 2e-08 33.9 7.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEQ34376.1 - 7.8e-07 29.2 10.6 7.8e-07 29.2 10.6 2.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EEQ34376.1 - 1.1e-06 28.6 8.2 1.1e-06 28.6 8.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ34376.1 - 2.1e-06 27.6 7.6 2.1e-06 27.6 7.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ34376.1 - 0.0016 18.3 6.7 0.0016 18.3 6.7 2.6 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 DZR PF12773.7 EEQ34376.1 - 0.0028 17.6 13.2 0.73 9.9 0.9 3.3 2 1 1 3 3 3 3 Double zinc ribbon zf-RING_4 PF14570.6 EEQ34376.1 - 0.014 15.2 2.9 0.014 15.2 2.9 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EEQ34376.1 - 0.031 14.5 7.2 0.031 14.5 7.2 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EEQ34376.1 - 0.035 14.1 2.8 0.035 14.1 2.8 1.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EEQ34376.1 - 1.1 9.4 5.3 2.3 8.4 5.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 EEQ34376.1 - 7.2 6.7 7.3 2.2 8.3 2.0 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-RING_6 PF14835.6 EEQ34376.1 - 9.5 6.2 9.7 0.39 10.6 3.9 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF2527 PF10736.9 EEQ34377.1 - 0.047 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) CHCH PF06747.13 EEQ34378.1 - 2e-05 24.6 4.8 2e-05 24.6 4.8 1.8 2 0 0 2 2 2 1 CHCH domain MTCP1 PF08991.10 EEQ34378.1 - 0.00083 19.5 1.8 0.0013 18.9 1.8 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 EEQ34378.1 - 0.049 13.9 6.1 0.14 12.4 4.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 EEQ34378.1 - 0.19 12.1 3.8 0.97 9.8 2.6 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NatB_MDM20 PF09797.9 EEQ34379.1 - 1.6e-104 349.9 0.3 2.5e-104 349.3 0.3 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EEQ34379.1 - 4.9e-05 23.8 9.7 0.0037 17.7 0.2 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ34379.1 - 0.0086 16.8 5.3 59 4.9 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat PIN PF01850.21 EEQ34379.1 - 0.052 14.1 0.3 2.1 8.9 0.3 2.7 2 0 0 2 2 2 0 PIN domain FANCI_S3 PF14677.6 EEQ34379.1 - 0.065 12.9 0.3 0.14 11.8 0.3 1.5 1 0 0 1 1 1 0 FANCI solenoid 3 TPR_6 PF13174.6 EEQ34379.1 - 0.39 11.4 1.3 37 5.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Proteasome PF00227.26 EEQ34380.1 - 2.7e-41 141.2 0.0 3.1e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 EEQ34381.1 - 2e-24 85.6 0.8 4.9e-24 84.3 0.1 2.1 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EEQ34381.1 - 5.1e-06 26.6 0.1 2.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 UBX domain RBD PF02196.15 EEQ34381.1 - 0.0042 17.1 0.1 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Raf-like Ras-binding domain Ribosomal_L36e PF01158.18 EEQ34382.1 - 3e-38 130.0 7.0 3.3e-38 129.8 7.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 EEQ34382.1 - 0.038 14.0 0.4 0.043 13.9 0.4 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF4239 PF14023.6 EEQ34382.1 - 0.1 12.3 0.1 0.13 12.0 0.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) TetR_C_9 PF14514.6 EEQ34382.1 - 0.12 12.5 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MRP-L28 PF09812.9 EEQ34382.1 - 0.14 12.3 2.8 0.17 12.0 2.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF2207 PF09972.9 EEQ34382.1 - 0.16 10.7 0.1 0.17 10.6 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PRTase_3 PF15610.6 EEQ34383.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like HATPase_c PF02518.26 EEQ34384.1 - 4.2e-19 69.1 0.0 7.5e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EEQ34384.1 - 1.7e-15 57.2 0.5 2e-09 37.6 0.1 3.4 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 EEQ34384.1 - 9e-05 22.4 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EEQ34384.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase M20_dimer PF07687.14 EEQ34385.1 - 1e-19 70.5 0.0 2.2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EEQ34385.1 - 2e-15 57.0 0.2 9.2e-12 45.1 0.1 2.3 2 1 0 2 2 2 2 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EEQ34385.1 - 0.00044 19.4 0.0 0.0083 15.2 0.0 2.3 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF373 PF04123.13 EEQ34385.1 - 0.0068 15.9 0.3 0.0068 15.9 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF373) Peptidase_M28 PF04389.17 EEQ34385.1 - 0.04 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Glyco_hydro_47 PF01532.20 EEQ34386.1 - 8.8e-165 549.0 0.0 1.2e-164 548.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.29 EEQ34387.1 - 7.2e-43 146.2 0.0 1.2e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EEQ34387.1 - 3.4e-11 42.9 0.0 9.5e-11 41.5 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EEQ34387.1 - 1.6e-10 40.6 0.1 3e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EEQ34387.1 - 2.8e-07 31.1 0.0 0.00012 22.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EEQ34387.1 - 1.8e-06 28.0 0.0 4.3e-05 23.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ34387.1 - 2.4e-06 27.8 0.0 8e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EEQ34387.1 - 6.9e-06 25.9 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ34387.1 - 0.00018 21.8 0.0 0.0031 17.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EEQ34387.1 - 0.00046 19.4 0.0 0.00096 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EEQ34387.1 - 0.0005 20.6 0.1 0.0033 18.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EEQ34387.1 - 0.00056 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EEQ34387.1 - 0.0019 17.5 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 EEQ34387.1 - 0.0041 16.7 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 EEQ34387.1 - 0.0041 17.3 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EEQ34387.1 - 0.0048 16.3 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EEQ34387.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EEQ34387.1 - 0.0074 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EEQ34387.1 - 0.0074 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 EEQ34387.1 - 0.0091 15.7 0.0 0.03 14.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EEQ34387.1 - 0.0093 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EEQ34387.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EEQ34387.1 - 0.032 13.6 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EEQ34387.1 - 0.034 13.9 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ34387.1 - 0.074 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EEQ34387.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 EEQ34387.1 - 0.097 12.4 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EEQ34387.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EEQ34387.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EEQ34387.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 EEQ34387.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EEQ34387.1 - 0.13 12.0 0.2 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cation_ATPase_C PF00689.21 EEQ34388.1 - 4e-44 150.5 3.2 4e-44 150.5 3.2 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EEQ34388.1 - 2.5e-39 134.7 2.6 2.5e-39 134.7 2.6 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EEQ34388.1 - 3.9e-21 76.3 0.0 6e-09 36.5 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ34388.1 - 1.1e-19 70.3 0.0 2.1e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EEQ34388.1 - 4.8e-10 39.0 0.0 1.1e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEQ34388.1 - 0.00016 21.5 0.3 0.0004 20.2 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEQ34388.1 - 0.002 18.5 0.0 0.26 11.7 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EEQ34388.1 - 0.77 9.5 6.8 1.3 8.8 0.9 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Wzy_C PF04932.15 EEQ34388.1 - 1.3 8.6 5.6 12 5.5 0.1 3.3 3 0 0 3 3 3 0 O-Antigen ligase Enolase_C PF00113.22 EEQ34389.1 - 4.2e-154 512.1 0.0 5.9e-154 511.6 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EEQ34389.1 - 4.4e-57 191.9 0.3 7.7e-57 191.1 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EEQ34389.1 - 1.2e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like eIF3_subunit PF08597.10 EEQ34390.1 - 1.5e-46 159.3 24.2 2e-45 155.6 14.6 2.0 1 1 1 2 2 2 2 Translation initiation factor eIF3 subunit HMG_box PF00505.19 EEQ34390.1 - 0.13 12.7 1.8 0.36 11.3 1.8 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box GREB1 PF15782.5 EEQ34390.1 - 5.6 3.9 6.4 6.8 3.7 6.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer 14-3-3 PF00244.20 EEQ34391.1 - 2.8e-106 354.0 3.4 3.7e-106 353.6 3.4 1.2 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 EEQ34391.1 - 0.0083 14.6 1.0 0.015 13.7 1.0 1.3 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP5 adh_short PF00106.25 EEQ34392.1 - 4.4e-20 72.0 0.0 6.2e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ34392.1 - 9.7e-08 31.8 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ34392.1 - 2.4e-05 24.3 0.1 3.9e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 KR domain E1-E2_ATPase PF00122.20 EEQ34393.1 - 1.9e-51 174.2 5.7 6.5e-50 169.2 2.1 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EEQ34393.1 - 1.3e-45 155.4 6.4 1.3e-45 155.4 6.4 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EEQ34393.1 - 1.6e-22 80.8 0.9 1.1e-21 78.1 0.9 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEQ34393.1 - 1.2e-18 66.6 0.1 3.8e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EEQ34393.1 - 4.8e-17 61.8 0.0 9.3e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEQ34393.1 - 4.7e-08 33.1 1.1 6.7e-06 26.0 1.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEQ34393.1 - 1.8e-06 28.5 0.0 7e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Proteasome_A_N PF10584.9 EEQ34393.1 - 0.022 14.4 0.2 0.19 11.4 0.0 2.4 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Peptidase_S8 PF00082.22 EEQ34394.1 - 1.1e-29 103.7 18.6 2.6e-29 102.5 18.6 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ34394.1 - 1.9e-15 57.3 0.3 3.3e-15 56.5 0.3 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 MBOAT_2 PF13813.6 EEQ34396.1 - 4.2e-21 75.0 3.9 9e-21 73.9 3.9 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Apt1 PF10351.9 EEQ34397.1 - 2 7.2 5.2 2.2 7.0 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM76 PF16046.5 EEQ34397.1 - 2.9 7.2 4.3 3.6 6.9 4.3 1.1 1 0 0 1 1 1 0 FAM76 protein Macoilin PF09726.9 EEQ34397.1 - 4.4 5.8 8.7 5.3 5.5 8.7 1.0 1 0 0 1 1 1 0 Macoilin family DnaJ PF00226.31 EEQ34398.1 - 1.5e-09 37.9 0.4 2.6e-09 37.1 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EEQ34398.1 - 0.0035 17.6 0.9 0.0068 16.7 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF456) MFS_1 PF07690.16 EEQ34399.1 - 3.5e-39 134.7 52.1 4e-38 131.3 52.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ34399.1 - 4e-08 32.1 22.9 4e-08 32.1 22.9 1.8 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PMM PF03332.13 EEQ34400.1 - 3.3e-80 269.0 1.4 1.1e-44 152.8 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EEQ34400.1 - 0.0097 15.7 0.0 3.9 7.1 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1640 PF07798.11 EEQ34401.1 - 3.9e-57 193.1 7.0 5.1e-57 192.7 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4476 PF14771.6 EEQ34401.1 - 0.065 13.6 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) VitD-bind_III PF09164.10 EEQ34401.1 - 0.14 12.1 0.1 0.37 10.8 0.1 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Trypsin_2 PF13365.6 EEQ34402.1 - 9.2e-25 88.3 0.0 1.3e-24 87.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EEQ34402.1 - 0.0005 19.9 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Trypsin Peptidase_S32 PF05579.13 EEQ34402.1 - 0.18 11.0 0.0 0.97 8.6 0.0 1.9 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Eisosome1 PF12757.7 EEQ34403.1 - 1e-28 100.1 2.6 1e-28 100.1 2.6 2.7 3 0 0 3 3 3 1 Eisosome protein 1 CAP PF00188.26 EEQ34403.1 - 0.061 14.2 0.5 0.23 12.3 0.4 2.1 2 0 0 2 2 2 0 Cysteine-rich secretory protein family MFS_1 PF07690.16 EEQ34404.1 - 2.7e-16 59.4 35.3 4.4e-16 58.7 35.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily HlyIII PF03006.20 EEQ34404.1 - 4.3e-05 23.3 6.9 0.0021 17.8 0.1 3.4 2 1 0 3 3 3 2 Haemolysin-III related Sugar_tr PF00083.24 EEQ34404.1 - 9.6e-05 21.4 10.2 9.6e-05 21.4 10.2 2.5 2 1 0 3 3 3 1 Sugar (and other) transporter TRIQK PF15168.6 EEQ34404.1 - 2.4 8.1 3.8 2.4 8.1 0.1 2.6 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Pkinase PF00069.25 EEQ34405.1 - 1.3e-47 162.4 0.0 2e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34405.1 - 5.9e-26 91.3 0.0 9.5e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ34405.1 - 1.6e-08 34.3 0.0 2.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEQ34405.1 - 1.2e-05 24.5 0.0 1.2e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain PRKG1_interact PF15898.5 EEQ34405.1 - 0.0096 16.8 3.1 0.029 15.3 3.1 1.8 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain Kdo PF06293.14 EEQ34405.1 - 0.023 14.1 0.1 0.023 14.1 0.1 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ferlin_C PF16165.5 EEQ34405.1 - 0.24 11.3 0.5 0.42 10.5 0.5 1.3 1 0 0 1 1 1 0 Ferlin C-terminus APH PF01636.23 EEQ34405.1 - 0.24 11.3 3.0 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Nop53 PF07767.11 EEQ34405.1 - 1.2 8.4 11.1 2.3 7.5 11.1 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4778 PF16008.5 EEQ34405.1 - 5.6 6.9 8.7 0.69 9.9 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Prenyltrans PF00432.21 EEQ34406.1 - 6.4e-31 105.8 9.9 2.3e-07 30.4 0.0 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EEQ34406.1 - 0.00058 19.0 0.0 0.0078 15.3 0.0 2.4 1 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Ilm1 PF10311.9 EEQ34407.1 - 1.6e-56 190.5 0.2 2e-56 190.2 0.2 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 AbLIM_anchor PF16182.5 EEQ34407.1 - 0.15 11.9 6.1 0.21 11.4 6.1 1.1 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM CFEM PF05730.11 EEQ34409.1 - 3.1e-13 49.6 12.2 5e-13 48.9 12.2 1.3 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.9 EEQ34409.1 - 3.4 6.7 9.3 4 6.5 9.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Corona_nucleoca PF00937.18 EEQ34409.1 - 3.6 6.5 8.9 1.7 7.6 6.5 1.6 1 1 1 2 2 2 0 Coronavirus nucleocapsid protein MFS_1 PF07690.16 EEQ34410.1 - 7.4e-35 120.5 27.1 7.4e-35 120.5 27.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ34410.1 - 6.1e-08 32.0 11.9 6.1e-08 32.0 11.9 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter Gly-zipper_Omp PF13488.6 EEQ34410.1 - 0.77 9.8 3.8 0.77 9.8 0.4 2.7 2 0 0 2 2 2 0 Glycine zipper MFS_1 PF07690.16 EEQ34411.1 - 1.5e-12 47.2 40.8 1.5e-12 47.2 40.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EEQ34411.1 - 3.6e-10 39.8 7.0 3.6e-10 39.8 7.0 3.0 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 MacB_PCD PF12704.7 EEQ34411.1 - 1.6 9.1 5.1 16 5.8 0.0 2.6 2 0 0 2 2 2 0 MacB-like periplasmic core domain BcrAD_BadFG PF01869.20 EEQ34413.1 - 2.1e-07 30.7 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 EEQ34413.1 - 4.1e-06 26.9 0.0 1.3e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 SIS domain SIS PF01380.22 EEQ34413.1 - 0.006 16.4 0.2 0.028 14.3 0.0 2.0 2 0 0 2 2 2 1 SIS domain ADP_ribosyl_GH PF03747.14 EEQ34414.1 - 8.7e-41 140.5 0.0 5.6e-39 134.6 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylglycohydrolase Carb_anhydrase PF00194.21 EEQ34415.1 - 2.5e-26 92.8 3.0 1.1e-14 54.6 0.2 2.1 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase IFS PF16718.5 EEQ34416.1 - 0.074 13.2 0.2 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 Immunity factor for SPN Ndc1_Nup PF09531.10 EEQ34417.1 - 0.11 11.1 11.1 0.16 10.7 11.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup F-box-like PF12937.7 EEQ34418.1 - 0.076 12.9 0.2 0.22 11.5 0.2 1.8 1 0 0 1 1 1 0 F-box-like DUF1980 PF09323.10 EEQ34419.1 - 2.9 7.8 13.1 10 6.0 2.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) DnaJ PF00226.31 EEQ34420.1 - 5.1e-08 32.9 0.1 4.5e-07 29.9 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain Acetyltransf_10 PF13673.7 EEQ34421.1 - 2.9e-12 46.6 0.0 1.2e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ34421.1 - 7.1e-10 39.2 0.0 2.3e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ34421.1 - 1.2e-09 38.4 0.0 2.3e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EEQ34421.1 - 2.5e-06 27.6 0.0 5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ34421.1 - 0.00011 22.1 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 EEQ34421.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PRA1 PF03208.19 EEQ34422.1 - 7.6e-28 96.9 3.8 1.3e-27 96.1 3.6 1.5 2 0 0 2 2 2 1 PRA1 family protein APH PF01636.23 EEQ34423.1 - 0.00028 20.9 0.0 0.002 18.1 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Frag1 PF10277.9 EEQ34424.1 - 3.6e-32 111.7 11.3 4.1e-32 111.5 11.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family HNF-1A_C PF04813.12 EEQ34424.1 - 0.017 15.9 1.0 5 8.0 0.8 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus DUF373 PF04123.13 EEQ34424.1 - 0.029 13.8 4.8 0.038 13.4 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Patched PF02460.18 EEQ34424.1 - 0.095 10.8 2.3 0.15 10.1 2.3 1.2 1 0 0 1 1 1 0 Patched family GWT1 PF06423.12 EEQ34424.1 - 0.16 12.0 4.8 0.72 10.0 4.8 2.0 1 1 0 1 1 1 0 GWT1 DUF2070 PF09843.9 EEQ34424.1 - 0.17 10.1 13.5 0.26 9.6 13.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Arteri_Gl PF00951.18 EEQ34424.1 - 0.39 10.5 8.0 0.13 12.1 4.3 1.9 1 1 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF3995 PF13160.6 EEQ34424.1 - 0.72 10.2 7.7 0.23 11.8 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3995) MFS_Mycoplasma PF07672.13 EEQ34424.1 - 1.4 8.1 11.2 4.3 6.5 9.9 2.2 1 1 0 1 1 1 0 Mycoplasma MFS transporter DUF2569 PF10754.9 EEQ34424.1 - 2.5 8.5 13.8 6 7.3 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) MFS_1 PF07690.16 EEQ34425.1 - 4.1e-41 141.1 28.1 6.6e-41 140.4 28.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ34425.1 - 1.7e-11 43.6 12.3 1.7e-11 43.6 12.3 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter SNF2_N PF00176.23 EEQ34426.1 - 2.1e-57 194.4 0.0 3.9e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 EEQ34426.1 - 6e-10 38.8 8.7 1.5e-09 37.5 8.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ34426.1 - 2.6e-09 36.8 8.5 7.1e-09 35.4 8.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ34426.1 - 2.5e-08 33.7 7.7 6.2e-08 32.4 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ34426.1 - 1.7e-07 31.4 11.5 4.5e-07 30.1 11.5 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EEQ34426.1 - 4.4e-07 29.7 8.9 9.5e-07 28.6 8.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EEQ34426.1 - 2.5e-05 24.5 7.8 7.9e-05 22.9 7.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEQ34426.1 - 3.3e-05 23.8 5.4 3.6e-05 23.7 3.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Helicase_C PF00271.31 EEQ34426.1 - 4.4e-05 23.8 0.0 9.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EEQ34426.1 - 0.00042 20.2 8.3 0.00097 19.1 8.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EEQ34426.1 - 0.00062 19.9 8.4 0.0015 18.6 8.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 EEQ34426.1 - 0.0071 16.4 0.0 0.07 13.1 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Baculo_IE-1 PF05290.11 EEQ34426.1 - 0.0078 16.2 0.5 0.019 14.9 0.5 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 EEQ34426.1 - 0.052 13.7 1.7 0.19 11.9 1.7 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 EEQ34426.1 - 0.11 12.3 5.4 0.34 10.7 5.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EEQ34426.1 - 0.13 12.4 5.2 0.34 11.1 5.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EEQ34426.1 - 0.28 11.3 3.3 0.66 10.1 3.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 EEQ34426.1 - 0.69 9.6 5.5 1.8 8.3 5.5 1.7 1 0 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 EEQ34426.1 - 1.1 8.9 7.7 2.6 7.7 7.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EEQ34426.1 - 8.8 6.7 10.1 21 5.5 10.1 1.7 1 0 0 1 1 1 0 RING-like domain Mito_carr PF00153.27 EEQ34427.1 - 5e-64 212.3 0.1 4.9e-21 74.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Bacteriocin_IIc PF10439.9 EEQ34427.1 - 0.043 14.0 6.0 6.5 6.9 0.1 3.3 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide PT-VENN PF04829.13 EEQ34427.1 - 0.15 12.2 0.6 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Ecm29 PF13001.7 EEQ34428.1 - 9.4e-151 502.9 1.1 4.2e-146 487.5 0.0 4.2 3 1 1 4 4 4 3 Proteasome stabiliser HEAT_EZ PF13513.6 EEQ34428.1 - 3.3e-05 24.3 5.5 1.9 9.1 0.0 6.8 8 0 0 8 8 8 2 HEAT-like repeat HEAT PF02985.22 EEQ34428.1 - 4e-05 23.5 5.1 13 6.4 0.0 9.1 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.6 EEQ34428.1 - 0.0042 17.4 8.0 2.4 8.6 0.7 6.5 5 2 2 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EEQ34428.1 - 0.048 14.3 1.7 0.6 10.7 0.1 4.0 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region Fungal_trans_2 PF11951.8 EEQ34430.1 - 5.7e-16 58.3 3.5 3.5e-11 42.6 0.0 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain Stm1_N PF09598.10 EEQ34430.1 - 2 9.3 5.0 4.9 8.1 5.0 1.6 1 0 0 1 1 1 0 Stm1 Peptidase_C14 PF00656.22 EEQ34431.1 - 0.00046 20.2 0.0 0.00065 19.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EEQ34431.1 - 0.016 15.2 0.2 0.12 12.3 0.2 2.3 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain Peptidase_C13 PF01650.18 EEQ34431.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family DUF3176 PF11374.8 EEQ34432.1 - 1.2e-35 122.0 1.2 2.8e-35 120.8 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) WW PF00397.26 EEQ34433.1 - 1.1e-11 44.6 0.6 2.5e-11 43.5 0.6 1.7 1 0 0 1 1 1 1 WW domain DUF4585 PF15232.6 EEQ34433.1 - 0.007 16.4 0.0 0.035 14.1 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4585) PhoD PF09423.10 EEQ34433.1 - 0.086 11.8 0.2 0.15 11.1 0.2 1.3 1 0 0 1 1 1 0 PhoD-like phosphatase Lipase_3 PF01764.25 EEQ34434.1 - 2.4e-31 108.5 0.0 3.7e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 EEQ34434.1 - 0.0045 16.8 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EEQ34434.1 - 0.0051 17.4 0.1 0.0072 17.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family GHMP_kinases_C PF08544.13 EEQ34434.1 - 0.018 15.4 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 GHMP kinases C terminal DUF4006 PF13179.6 EEQ34434.1 - 0.039 13.9 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Hydrolase_4 PF12146.8 EEQ34434.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 EEQ34434.1 - 0.083 12.4 0.0 0.84 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Esterase PF00756.20 EEQ34434.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase WD40 PF00400.32 EEQ34435.1 - 8.6e-13 48.6 14.0 0.0087 16.9 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ34435.1 - 2.3e-06 27.8 0.0 0.0033 17.7 0.0 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ34435.1 - 0.1 11.6 0.0 6.4 5.6 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RRM_1 PF00076.22 EEQ34436.1 - 1.1e-07 31.6 0.0 2.7e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ34436.1 - 0.00017 21.2 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ34436.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EEQ34436.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Autophagy_act_C PF03987.15 EEQ34437.1 - 3.5e-15 56.3 0.1 7.6e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Sulfatase PF00884.23 EEQ34438.1 - 8.1e-79 265.2 0.0 1e-78 264.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EEQ34438.1 - 1.2e-05 24.2 0.0 3.2e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Herpes_pp38 PF04846.13 EEQ34439.1 - 0.65 10.0 5.5 7.2 6.6 0.3 3.2 3 0 0 3 3 3 0 Herpesvirus pp38 phosphoprotein MFS_1 PF07690.16 EEQ34440.1 - 5e-11 42.1 54.9 4.3e-07 29.2 19.6 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Bac_rhodopsin PF01036.18 EEQ34442.1 - 1.4e-24 86.9 12.7 1.7e-24 86.6 12.7 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HSP20 PF00011.21 EEQ34445.1 - 2.4e-19 69.3 0.2 4.4e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EEQ34445.1 - 4.1e-06 26.2 0.0 4.2e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FAA_hydrolase PF01557.18 EEQ34446.1 - 5.2e-65 219.2 0.0 6.8e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 EEQ34446.1 - 0.028 14.9 0.3 0.046 14.1 0.3 1.3 1 0 0 1 1 1 0 Type II transport protein GspH Proteasome PF00227.26 EEQ34447.1 - 5e-27 94.6 0.0 6.1e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.13 EEQ34448.1 - 3e-29 101.5 0.2 5e-29 100.8 0.2 1.3 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 EEQ34449.1 - 1.2e-31 109.7 0.1 2.9e-31 108.5 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit KH_8 PF17903.1 EEQ34450.1 - 5.1e-06 26.5 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EEQ34450.1 - 0.089 12.6 1.9 0.098 12.5 0.6 1.7 2 0 0 2 2 2 0 KH domain MDM31_MDM32 PF08118.11 EEQ34451.1 - 6.6e-249 826.9 2.6 3.9e-248 824.4 2.6 1.8 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins RhoGAP PF00620.27 EEQ34452.1 - 1e-40 139.1 0.0 2.2e-40 138.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EEQ34452.1 - 5.3e-14 52.6 0.0 1.3e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4763 PF15960.5 EEQ34452.1 - 0.0022 17.3 0.3 0.0058 16.0 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) PH_8 PF15409.6 EEQ34452.1 - 0.02 15.1 0.1 0.063 13.6 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DDE_Tnp_IS66 PF03050.14 EEQ34452.1 - 0.17 11.3 1.0 0.36 10.3 1.0 1.4 1 0 0 1 1 1 0 Transposase IS66 family PRTP PF01366.18 EEQ34452.1 - 8.2 4.3 8.4 0.28 9.2 0.6 2.1 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Erv26 PF04148.13 EEQ34453.1 - 2.9e-65 219.9 0.1 4.1e-57 193.3 0.0 2.1 1 1 1 2 2 2 2 Transmembrane adaptor Erv26 WBS_methylT PF12589.8 EEQ34454.1 - 2e-14 54.1 3.9 3.4e-14 53.4 3.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EEQ34454.1 - 3.2e-10 40.5 0.0 6.6e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ34454.1 - 5.5e-10 39.8 0.0 2.3e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ34454.1 - 0.00024 20.9 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ34454.1 - 0.00034 21.3 0.0 0.00086 20.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EEQ34454.1 - 0.00065 19.5 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EEQ34454.1 - 0.0027 17.1 0.0 0.033 13.5 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EEQ34454.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 EEQ34454.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Iso_dh PF00180.20 EEQ34455.1 - 9.1e-84 281.6 0.0 1.1e-83 281.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Vps36-NZF-N PF16988.5 EEQ34458.1 - 0.11 11.9 0.1 0.34 10.3 0.1 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Proteasome PF00227.26 EEQ34459.1 - 8.8e-46 155.8 0.2 4.1e-32 111.2 0.0 2.8 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 EEQ34459.1 - 5.6e-12 45.1 1.0 6.8e-12 44.8 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DMRL_synthase PF00885.19 EEQ34460.1 - 5e-58 194.9 0.0 5.9e-58 194.7 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SIS PF01380.22 EEQ34461.1 - 4e-56 188.4 0.0 3.9e-31 107.6 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EEQ34461.1 - 1.4e-17 64.1 0.0 2.8e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EEQ34461.1 - 3e-11 43.3 0.0 6.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EEQ34461.1 - 7.2e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 EEQ34461.1 - 0.041 13.9 0.0 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 SIS domain N-SET PF11764.8 EEQ34462.1 - 1.2e-57 194.8 0.7 1.2e-57 194.8 0.7 2.5 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EEQ34462.1 - 2.2e-27 94.5 0.3 6e-27 93.1 0.3 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 EEQ34462.1 - 9e-20 71.7 0.2 9e-20 71.7 0.2 3.9 4 1 0 4 4 4 1 SET domain RRM_1 PF00076.22 EEQ34462.1 - 1.2e-05 25.1 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEQ34462.1 - 0.19 11.7 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Trm112p PF03966.16 EEQ34463.1 - 1e-14 54.8 0.1 1.3e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Rad60-SLD PF11976.8 EEQ34464.1 - 2.2e-21 75.5 0.2 3.1e-20 71.8 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EEQ34464.1 - 0.0098 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family YL1 PF05764.13 EEQ34464.1 - 0.46 10.6 18.5 0.031 14.4 1.9 2.4 3 0 0 3 3 3 0 YL1 nuclear protein PBP1_TM PF14812.6 EEQ34464.1 - 3.7 8.0 9.1 17 5.9 0.6 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LSM PF01423.22 EEQ34465.1 - 9.1e-20 70.1 0.0 1e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEQ34465.1 - 0.0022 18.1 0.1 0.0026 17.9 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EEQ34465.1 - 0.032 14.3 0.1 0.037 14.1 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain Hfq PF17209.3 EEQ34465.1 - 0.091 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Hfq protein DUF1106 PF06523.11 EEQ34465.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) IF-2B PF01008.17 EEQ34466.1 - 2.6e-70 236.9 1.0 3e-70 236.6 1.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family KxDL PF10241.9 EEQ34467.1 - 0.011 16.0 0.1 0.014 15.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF4446 PF14584.6 EEQ34467.1 - 0.093 12.7 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Exonuc_VII_S PF02609.16 EEQ34467.1 - 0.25 11.4 4.0 0.35 11.0 0.3 2.5 3 0 0 3 3 3 0 Exonuclease VII small subunit GST_N PF02798.20 EEQ34469.1 - 2.8e-13 50.0 0.0 5.4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEQ34469.1 - 1.9e-12 47.2 0.1 2.7e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EEQ34469.1 - 3.4e-12 46.6 0.0 5.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ34469.1 - 1.1e-07 31.8 0.2 2e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EEQ34469.1 - 1.2e-07 31.9 0.1 5.1e-07 29.9 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EEQ34469.1 - 1.2e-07 31.8 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RAMP4 PF06624.12 EEQ34471.1 - 0.0032 17.5 0.7 0.0089 16.1 0.7 1.8 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Adaptin_N PF01602.20 EEQ34472.1 - 7.2e-59 199.7 0.0 2.5e-58 197.9 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 EEQ34472.1 - 0.069 13.4 0.1 20 5.8 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 EEQ34472.1 - 0.1 13.1 2.7 25 5.5 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat TFIIF_alpha PF05793.12 EEQ34472.1 - 2.2 6.7 19.4 0.039 12.6 11.7 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPR_14 PF13428.6 EEQ34473.1 - 4.1e-08 33.4 4.8 0.028 15.2 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ34473.1 - 7.5e-07 29.6 1.1 0.012 16.1 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ34473.1 - 8.5e-05 22.5 0.0 0.011 15.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ34473.1 - 0.00031 20.6 0.4 0.04 14.0 0.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ34473.1 - 0.00064 19.9 0.1 0.16 12.4 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ34473.1 - 0.00087 19.9 1.4 0.25 12.0 0.0 3.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ34473.1 - 0.0053 16.4 0.0 2.1 8.1 0.2 3.4 2 1 1 3 3 3 2 TPR repeat Wzy_C_2 PF11846.8 EEQ34473.1 - 0.057 13.3 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_1 PF00515.28 EEQ34473.1 - 0.09 12.6 0.0 1.9 8.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Get5_C PF18514.1 EEQ34473.1 - 0.14 11.9 0.1 7.5 6.4 0.0 2.9 3 0 0 3 3 3 0 Get5 C-terminal domain RNA_pol_3_Rpc31 PF11705.8 EEQ34475.1 - 0.00018 21.8 1.6 0.00018 21.8 1.6 2.9 2 1 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 BAF1_ABF1 PF04684.13 EEQ34475.1 - 0.044 12.9 5.6 0.0084 15.2 1.0 1.9 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Spem1 PF15670.5 EEQ34475.1 - 6.2 6.3 9.3 15 5.1 9.3 1.6 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF2052 PF09747.9 EEQ34475.1 - 6.5 6.8 23.7 0.21 11.7 2.6 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Kinesin PF00225.23 EEQ34477.1 - 1.3e-96 323.4 0.1 2.8e-96 322.3 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ34477.1 - 2.3e-23 82.8 0.2 3.2e-21 75.8 0.0 2.7 3 0 0 3 3 3 1 Microtubule binding MPS2 PF17060.5 EEQ34477.1 - 0.024 13.9 0.1 0.024 13.9 0.1 1.7 2 0 0 2 2 2 0 Monopolar spindle protein 2 FlxA PF14282.6 EEQ34477.1 - 0.094 12.7 7.8 0.16 11.9 2.6 3.8 3 0 0 3 3 3 0 FlxA-like protein MoCF_biosynth PF00994.24 EEQ34477.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Probable molybdopterin binding domain BBP1_C PF15272.6 EEQ34477.1 - 0.26 11.1 8.0 4.5 7.0 1.3 3.1 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Tho2 PF11262.8 EEQ34477.1 - 0.62 9.2 3.9 1.1 8.3 3.9 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4746 PF15928.5 EEQ34477.1 - 7.4 5.9 5.9 40 3.5 2.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4746) Ank_2 PF12796.7 EEQ34478.1 - 4.8e-81 267.4 7.6 5.5e-16 58.9 0.0 7.0 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ34478.1 - 2.2e-54 181.1 1.4 7e-10 39.3 0.0 9.4 3 3 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ34478.1 - 3.8e-54 174.3 0.3 0.0012 19.1 0.0 12.4 12 0 0 12 12 12 10 Ankyrin repeat Ank PF00023.30 EEQ34478.1 - 7.8e-50 165.2 0.5 0.0003 21.1 0.1 12.0 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 EEQ34478.1 - 4.2e-46 154.4 6.0 1.5e-08 34.7 0.1 8.2 2 2 6 9 9 9 8 Ankyrin repeats (many copies) PEGA PF08308.11 EEQ34478.1 - 0.0032 17.3 0.0 4.5 7.2 0.0 4.6 6 0 0 6 6 6 1 PEGA domain VWA_3_C PF18571.1 EEQ34478.1 - 0.42 10.5 0.0 0.42 10.5 0.0 4.2 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain NOGCT PF08155.11 EEQ34480.1 - 0.11 12.5 0.2 0.3 11.1 0.2 1.7 1 0 0 1 1 1 0 NOGCT (NUC087) domain DAGAT PF03982.13 EEQ34481.1 - 2e-90 302.7 0.0 2.4e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 EEQ34481.1 - 0.013 15.2 1.4 0.025 14.3 1.4 1.4 1 0 0 1 1 1 0 Rer1 family G-patch PF01585.23 EEQ34483.1 - 0.00095 19.0 0.1 0.014 15.3 0.1 2.7 1 1 0 1 1 1 1 G-patch domain DUF5521 PF17659.1 EEQ34483.1 - 0.13 10.0 8.2 0.17 9.7 8.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Coilin_N PF15862.5 EEQ34483.1 - 0.39 10.5 27.9 0.046 13.5 8.8 2.3 2 0 0 2 2 2 0 Coilin N-terminus Baculo_PP31 PF05311.11 EEQ34483.1 - 0.99 8.8 19.2 0.035 13.6 3.7 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Hid1 PF12722.7 EEQ34483.1 - 1.4 7.0 14.8 1.7 6.7 14.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1168 PF06658.12 EEQ34483.1 - 1.6 8.5 39.7 0.54 10.1 18.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) U1snRNP70_N PF12220.8 EEQ34483.1 - 2.3 8.9 20.1 8.1 7.2 0.8 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal GREB1 PF15782.5 EEQ34483.1 - 4.3 4.3 15.1 5.3 4.0 15.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 EEQ34483.1 - 5.6 5.7 20.2 7.6 5.3 20.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLC12 PF03522.15 EEQ34483.1 - 6.7 5.6 15.1 9.3 5.1 15.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF3450 PF11932.8 EEQ34484.1 - 0.038 13.3 5.3 0.055 12.8 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2852 PF11014.8 EEQ34484.1 - 0.043 14.0 1.2 0.052 13.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF4661 PF15576.6 EEQ34484.1 - 0.17 11.8 2.4 0.19 11.6 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Syja_N PF02383.18 EEQ34485.1 - 2.8e-72 243.8 0.0 4.5e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EEQ34485.1 - 1.5e-08 34.4 0.0 2.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 EEQ34486.1 - 1e-56 192.3 0.0 1.3e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34486.1 - 5.7e-30 104.5 0.0 8.5e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ34486.1 - 0.13 11.1 0.2 1.9 7.3 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 EEQ34486.1 - 0.19 11.0 0.0 0.42 9.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like IGR PF09597.10 EEQ34487.1 - 7e-21 74.1 2.4 1.2e-20 73.3 2.4 1.4 1 0 0 1 1 1 1 IGR protein motif p450 PF00067.22 EEQ34488.1 - 3.6e-70 237.0 0.0 4.5e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3045 PF11243.8 EEQ34488.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) Pkinase PF00069.25 EEQ34489.1 - 3.9e-67 226.4 0.0 5.1e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34489.1 - 1.9e-34 119.2 0.0 2.6e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EEQ34489.1 - 4.2e-16 59.1 0.5 8e-16 58.1 0.5 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EEQ34489.1 - 4e-06 26.4 0.0 0.00067 19.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Yop-YscD_cpl PF16697.5 EEQ34489.1 - 4.7e-05 23.6 0.0 9.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 EEQ34489.1 - 0.001 17.9 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EEQ34489.1 - 0.015 14.3 0.1 0.021 13.8 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EEQ34489.1 - 0.036 13.4 0.1 0.059 12.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EEQ34489.1 - 0.076 12.0 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2961 PF11175.8 EEQ34489.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) PI3_PI4_kinase PF00454.27 EEQ34490.1 - 6.7e-37 127.6 0.0 1.6e-34 119.8 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EEQ34490.1 - 1.3e-24 86.7 0.2 2.8e-24 85.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EEQ34490.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CorA PF01544.18 EEQ34492.1 - 0.45 9.8 5.1 1.2 8.4 5.0 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein ArfGap PF01412.18 EEQ34494.1 - 1.6e-32 112.1 0.0 1.6e-32 112.1 0.0 2.6 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EEQ34494.1 - 2.9e-20 73.0 9.1 5.1e-20 72.2 9.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EEQ34494.1 - 5.4e-13 49.4 0.2 1.9e-12 47.6 0.2 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EEQ34494.1 - 0.005 17.2 0.2 0.016 15.6 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EEQ34494.1 - 0.17 12.2 0.6 1.1 9.6 0.6 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain LSM PF01423.22 EEQ34495.1 - 2.6e-21 75.1 0.1 2.9e-21 74.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEQ34495.1 - 0.024 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Ank_2 PF12796.7 EEQ34496.1 - 1.4e-50 169.8 0.9 1.8e-12 47.6 0.0 5.6 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ34496.1 - 4.5e-44 148.3 9.1 6.7e-07 29.7 0.7 10.7 3 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 EEQ34496.1 - 7.8e-35 117.8 12.2 8.6e-07 29.1 0.0 10.8 11 0 0 11 11 11 6 Ankyrin repeat Ank_3 PF13606.6 EEQ34496.1 - 7.8e-33 108.8 4.6 0.0023 18.3 0.1 11.8 11 1 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 EEQ34496.1 - 8.2e-28 96.1 11.1 2.3e-06 27.8 0.0 7.9 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Asp_protease_2 PF13650.6 EEQ34496.1 - 0.14 12.8 0.1 13 6.5 0.0 3.7 3 1 1 4 4 4 0 Aspartyl protease RVP PF00077.20 EEQ34496.1 - 0.18 12.1 0.0 7.7 6.9 0.0 3.2 4 0 0 4 4 4 0 Retroviral aspartyl protease AA_permease PF00324.21 EEQ34497.1 - 1.1e-132 443.0 35.2 1.4e-132 442.7 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ34497.1 - 5.1e-32 111.3 36.3 6.5e-32 110.9 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease APH PF01636.23 EEQ34498.1 - 0.00031 20.8 0.0 0.0036 17.3 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family RhoGAP PF00620.27 EEQ34499.1 - 8.1e-13 48.5 0.0 8.1e-13 48.5 0.0 2.5 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.23 EEQ34499.1 - 7.6e-11 42.1 0.4 1e-09 38.5 0.0 3.0 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 EEQ34499.1 - 1.8e-10 40.7 0.0 3.8e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CorA PF01544.18 EEQ34499.1 - 0.09 12.1 0.1 0.24 10.7 0.1 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cor1 PF04803.12 EEQ34499.1 - 8 6.7 11.3 4 7.7 6.2 2.5 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region RTA1 PF04479.13 EEQ34500.1 - 3.9e-33 114.8 3.0 5.5e-33 114.3 3.0 1.2 1 0 0 1 1 1 1 RTA1 like protein Asp-Al_Ex PF06826.12 EEQ34500.1 - 0.0083 16.0 0.6 0.015 15.1 0.6 1.4 1 0 0 1 1 1 1 Predicted Permease Membrane Region AAA PF00004.29 EEQ34501.1 - 4.7e-15 56.2 0.0 1.2e-14 54.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ34501.1 - 1.4e-13 51.3 0.0 3.5e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEQ34501.1 - 2.8e-11 44.1 1.0 6.7e-10 39.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Cdc6_C PF09079.11 EEQ34501.1 - 1.2e-07 31.6 0.0 3.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain TIP49 PF06068.13 EEQ34501.1 - 6.6e-06 25.6 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TniB PF05621.11 EEQ34501.1 - 1.1e-05 24.9 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_19 PF13245.6 EEQ34501.1 - 0.00038 20.8 0.0 0.00094 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 EEQ34501.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain KAP_NTPase PF07693.14 EEQ34501.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_7 PF12775.7 EEQ34501.1 - 0.0014 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EEQ34501.1 - 0.0041 17.7 0.0 0.0079 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EEQ34501.1 - 0.0044 16.3 0.0 0.01 15.1 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain T2SSE PF00437.20 EEQ34501.1 - 0.0061 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.14 EEQ34501.1 - 0.0087 16.1 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PIF1 PF05970.14 EEQ34501.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Rad17 PF03215.15 EEQ34501.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 EEQ34501.1 - 0.037 14.4 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EEQ34501.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 1 0 NTPase RuvB_N PF05496.12 EEQ34501.1 - 0.054 13.2 0.0 0.18 11.6 0.0 1.8 1 1 1 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EEQ34501.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EEQ34501.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EEQ34501.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EEQ34501.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 EEQ34501.1 - 0.089 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_28 PF13521.6 EEQ34501.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.9 EEQ34501.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein Thioredoxin_7 PF13899.6 EEQ34502.1 - 3.1e-16 59.3 0.0 7.1e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 EEQ34502.1 - 5.3e-14 51.8 0.0 1.1e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EEQ34502.1 - 2.2e-06 27.8 0.0 6.9e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 UBX domain CBP_CCPA PF17040.5 EEQ34502.1 - 0.065 13.8 0.2 0.83 10.3 0.0 2.5 2 0 0 2 2 2 0 Cellulose-complementing protein A Thioredoxin_2 PF13098.6 EEQ34502.1 - 0.072 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Pkinase PF00069.25 EEQ34504.1 - 1.1e-68 231.5 0.0 1.6e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34504.1 - 1.5e-49 168.6 0.0 2.2e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ34504.1 - 1.1e-05 24.4 0.2 4.7e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EEQ34504.1 - 0.019 14.3 0.0 0.45 9.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Fungal_trans PF04082.18 EEQ34505.1 - 5.3e-21 74.8 0.2 9.6e-21 74.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ34505.1 - 0.23 11.6 2.8 0.42 10.8 2.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.6 EEQ34506.1 - 8.8e-41 139.9 0.0 1.3e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EEQ34506.1 - 1.1e-08 35.3 0.0 1.8e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.6 EEQ34507.1 - 3e-51 174.3 0.0 9.9e-51 172.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ34507.1 - 2.5e-38 131.5 0.1 2e-37 128.6 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ34507.1 - 1.8e-06 28.0 0.2 5e-06 26.5 0.2 1.6 1 1 0 1 1 1 1 KR domain DUF3431 PF11913.8 EEQ34508.1 - 3.3e-85 285.2 0.0 4.3e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) YkyA PF10368.9 EEQ34508.1 - 0.092 12.4 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein MRP_L53 PF10780.9 EEQ34509.1 - 0.3 11.3 1.2 0.74 10.0 0.4 2.1 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 APH PF01636.23 EEQ34510.1 - 2.4e-10 40.8 0.0 3.6e-10 40.2 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ34510.1 - 0.00082 19.0 0.0 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EEQ34510.1 - 0.0038 16.5 0.0 0.0073 15.5 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase Amidohydro_2 PF04909.14 EEQ34511.1 - 1.2e-18 68.0 0.0 1.3e-17 64.5 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase ADH_N PF08240.12 EEQ34512.1 - 1.3e-25 89.4 0.4 2.4e-25 88.5 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ34512.1 - 5.9e-23 81.3 0.1 8.7e-23 80.7 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ34512.1 - 0.00011 23.3 0.0 0.00017 22.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EEQ34512.1 - 0.041 13.4 0.1 0.059 12.8 0.1 1.4 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus Peripla_BP_6 PF13458.6 EEQ34512.1 - 0.086 12.5 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein SWIM PF04434.17 EEQ34513.1 - 2.2e-06 27.2 0.1 4.1e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger RecC_C PF17946.1 EEQ34513.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 RecC C-terminal domain SpecificRecomb PF10136.9 EEQ34513.1 - 0.16 10.3 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase SET PF00856.28 EEQ34515.1 - 5.8e-08 33.3 0.1 0.00034 21.0 0.0 3.5 3 0 0 3 3 3 2 SET domain LolB PF03550.14 EEQ34515.1 - 0.051 13.6 0.2 0.69 9.9 0.0 2.4 1 1 0 2 2 2 0 Outer membrane lipoprotein LolB TPR_1 PF00515.28 EEQ34515.1 - 0.054 13.3 0.1 0.82 9.6 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ34515.1 - 0.1 12.7 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Allexi_40kDa PF05549.11 EEQ34516.1 - 0.00028 20.5 0.1 0.002 17.7 0.0 2.4 2 0 0 2 2 2 1 Allexivirus 40kDa protein Thioredoxin_4 PF13462.6 EEQ34516.1 - 4.2 7.5 7.1 1.2 9.2 0.1 2.9 2 1 1 3 3 3 0 Thioredoxin zf-H2C2_2 PF13465.6 EEQ34517.1 - 4.4e-10 39.5 16.2 9.4e-05 22.7 1.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EEQ34517.1 - 2.4e-07 30.8 23.9 0.024 15.1 7.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ34517.1 - 0.00021 21.9 20.9 0.15 12.9 5.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 EEQ34517.1 - 0.013 15.7 6.3 0.025 14.9 6.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 EEQ34517.1 - 0.02 14.9 19.2 0.14 12.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 EEQ34517.1 - 0.076 12.9 0.4 0.18 11.7 0.4 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 EEQ34517.1 - 0.13 12.6 7.4 1.7 9.0 2.4 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 EEQ34517.1 - 0.27 11.6 1.1 0.47 10.8 1.1 1.4 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2HE PF16278.5 EEQ34517.1 - 0.34 11.4 15.2 0.42 11.1 1.1 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 EEQ34517.1 - 0.53 10.2 2.0 2.4 8.0 0.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 EEQ34517.1 - 0.74 9.9 6.5 6.7 6.8 6.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon CCDC106 PF15794.5 EEQ34517.1 - 1.7 8.3 0.0 1.7 8.3 0.0 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 zf-BED PF02892.15 EEQ34517.1 - 2.1 8.4 9.9 6.5 6.9 5.5 2.7 1 1 1 2 2 2 0 BED zinc finger zf_C2H2_ZHX PF18387.1 EEQ34517.1 - 3.6 7.3 8.6 8.8 6.1 0.0 3.2 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 EEQ34517.1 - 3.8 7.9 11.0 3.8 7.9 1.7 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 EEQ34517.1 - 8.1 6.7 10.7 1.5 9.0 1.9 2.4 1 1 1 2 2 2 0 FYVE zinc finger DUF3074 PF11274.8 EEQ34518.1 - 2.2e-15 57.1 0.3 6e-07 29.6 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) Stk19 PF10494.9 EEQ34519.1 - 2e-84 283.2 0.0 2.6e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.21 EEQ34520.1 - 7.2e-105 351.4 2.9 6.7e-65 219.6 0.0 2.5 2 1 1 3 3 3 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EEQ34520.1 - 9.6e-37 126.3 0.0 3.6e-36 124.5 0.0 1.9 1 1 0 1 1 1 1 Trehalose-phosphatase DUF4795 PF16043.5 EEQ34520.1 - 0.029 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Glyco_trans_1_4 PF13692.6 EEQ34520.1 - 0.091 13.2 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 zf-C2H2_10 PF16588.5 EEQ34521.1 - 0.048 13.4 2.6 0.11 12.3 2.6 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger 4HBT_3 PF13622.6 EEQ34523.1 - 2.7e-49 168.7 0.1 3.1e-49 168.5 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EEQ34524.1 - 2.1e-07 31.2 0.0 3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Auts2 PF15336.6 EEQ34524.1 - 0.021 15.0 1.3 0.028 14.5 1.3 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein eIF3m_C_helix PF18005.1 EEQ34526.1 - 7.7e-12 44.7 3.5 1.5e-11 43.8 3.5 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 EEQ34526.1 - 1.4e-09 38.4 0.0 3.3e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain K_channel_TID PF07941.11 EEQ34526.1 - 0.2 12.1 7.5 0.49 10.9 7.5 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ribosomal_S14 PF00253.21 EEQ34527.1 - 1.3e-13 50.4 4.4 1.7e-13 50.1 4.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e ADK PF00406.22 EEQ34528.1 - 6e-40 136.8 0.0 9.2e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EEQ34528.1 - 1.1e-33 116.5 0.0 1.9e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEQ34528.1 - 1.5e-07 32.1 0.0 2.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ34528.1 - 0.00033 20.8 0.0 0.0033 17.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EEQ34528.1 - 0.013 15.1 0.0 0.21 11.2 0.0 2.1 1 1 0 1 1 1 0 Thymidylate kinase Ploopntkinase3 PF18751.1 EEQ34528.1 - 0.05 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MFS_1 PF07690.16 EEQ34529.1 - 1.3e-26 93.4 34.4 1.3e-26 93.4 34.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Glt_symporter PF03616.14 EEQ34529.1 - 0.095 11.4 8.6 0.023 13.4 1.1 2.2 2 0 0 2 2 2 0 Sodium/glutamate symporter Acyl_transf_3 PF01757.22 EEQ34529.1 - 6.8 5.6 33.6 0.99 8.4 12.0 2.4 2 1 0 2 2 2 0 Acyltransferase family Cnd2 PF05786.14 EEQ34531.1 - 0 1035.1 2.6 0 1034.8 2.6 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EEQ34531.1 - 0.014 15.6 0.0 0.046 13.9 0.0 1.9 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal SMN PF06003.12 EEQ34531.1 - 0.016 14.5 0.2 0.036 13.3 0.2 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Na_Ca_ex PF01699.24 EEQ34532.1 - 1.7e-48 164.4 48.4 2.4e-27 95.8 15.6 3.1 4 0 0 4 4 4 2 Sodium/calcium exchanger protein EF-hand_4 PF12763.7 EEQ34533.1 - 1e-24 86.5 0.0 1.6e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 EEQ34533.1 - 2.2e-10 40.0 0.2 6.2e-10 38.6 0.2 1.8 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.11 EEQ34533.1 - 2.8e-06 27.6 62.3 2.7e-05 24.5 34.0 7.0 5 2 2 7 7 7 2 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 EEQ34533.1 - 7.3e-05 22.0 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EEQ34533.1 - 0.0012 19.3 3.1 0.14 12.7 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EEQ34533.1 - 0.026 14.4 0.0 4.2 7.3 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair RNA_pol_L_2 PF13656.6 EEQ34534.1 - 2.6e-26 91.2 0.0 4.5e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EEQ34534.1 - 1.9e-09 36.8 0.0 3.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CorA PF01544.18 EEQ34534.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein NMO PF03060.15 EEQ34536.1 - 3e-29 102.5 3.3 1e-25 90.9 1.2 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EEQ34536.1 - 1.7e-07 30.6 5.2 2.8e-07 29.9 5.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EEQ34536.1 - 0.00019 20.7 0.8 0.00027 20.2 0.8 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EEQ34536.1 - 0.00019 20.5 1.1 0.0025 16.9 1.2 2.0 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain dbPDZ_assoc PF16610.5 EEQ34537.1 - 0.32 11.2 11.7 3.2 8.0 1.7 3.6 3 0 0 3 3 3 0 Unstructured region between two PDZ domains on Dlg5 Gar1 PF04410.14 EEQ34537.1 - 0.34 10.7 2.3 0.66 9.7 2.3 1.4 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region DNA_pol_phi PF04931.13 EEQ34537.1 - 6.3 4.8 7.8 9.3 4.2 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 EEQ34537.1 - 7 5.3 6.5 12 4.5 6.5 1.4 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 EEQ34538.1 - 1.3 8.7 8.5 0.023 14.4 2.0 1.5 2 0 0 2 2 2 0 FAM176 family AIM3 PF17096.5 EEQ34538.1 - 2.7 9.0 5.1 4.2 8.4 5.1 1.2 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Mur_ligase_M PF08245.12 EEQ34539.1 - 3.7e-05 23.8 0.0 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EEQ34539.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain LRR_4 PF12799.7 EEQ34540.1 - 0.0063 16.9 12.8 1.2 9.6 0.2 5.8 6 1 2 8 8 8 1 Leucine Rich repeats (2 copies) DUF4604 PF15377.6 EEQ34540.1 - 0.024 15.1 16.0 0.038 14.4 16.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) LRR_8 PF13855.6 EEQ34540.1 - 0.086 12.6 5.5 5.5 6.8 0.1 4.1 3 1 0 3 3 3 0 Leucine rich repeat TFIIF_beta_N PF17683.1 EEQ34540.1 - 0.15 12.7 1.1 0.4 11.4 1.1 1.7 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus Red1 PF07964.11 EEQ34540.1 - 0.16 10.2 6.0 0.22 9.7 6.0 1.2 1 0 0 1 1 1 0 Rec10 / Red1 LRR_6 PF13516.6 EEQ34540.1 - 0.17 12.0 9.1 25 5.3 0.1 5.5 7 0 0 7 7 7 0 Leucine Rich repeat CDC45 PF02724.14 EEQ34540.1 - 0.36 9.1 7.0 0.55 8.5 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.18 EEQ34540.1 - 0.87 9.4 7.5 1.5 8.7 7.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Paramyxo_ncap PF00973.19 EEQ34540.1 - 3.1 6.6 10.7 4.2 6.2 10.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SNF2_N PF00176.23 EEQ34541.1 - 2e-48 164.9 0.4 7.8e-48 163.0 0.0 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ34541.1 - 2.8e-16 59.8 0.0 1.4e-15 57.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ34541.1 - 2.9e-05 24.1 0.0 0.00013 22.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EEQ34541.1 - 9.5e-05 22.2 11.3 9.5e-05 22.2 11.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 EEQ34541.1 - 0.00025 20.0 0.0 0.0012 17.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.6 EEQ34541.1 - 0.0098 16.2 11.8 0.0098 16.2 11.8 2.6 2 0 0 2 2 2 1 Ring finger domain PBP_sp32 PF07222.12 EEQ34541.1 - 0.087 12.3 1.3 0.16 11.4 1.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Zn_Tnp_IS91 PF14319.6 EEQ34541.1 - 3.1 7.9 17.8 3.1 7.9 5.8 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain C2 PF00168.30 EEQ34542.1 - 1.6e-11 44.4 0.0 3.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pex2_Pex12 PF04757.14 EEQ34543.1 - 7.9e-42 143.4 2.5 1e-41 143.0 2.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EEQ34543.1 - 2.2e-11 43.4 9.5 3.5e-11 42.7 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ34543.1 - 7.7e-11 42.2 9.9 1.2e-10 41.5 9.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EEQ34543.1 - 1e-10 41.3 7.1 1.6e-10 40.7 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ34543.1 - 2.6e-10 40.0 5.6 4e-10 39.4 5.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ34543.1 - 2.1e-08 34.0 8.6 4.2e-08 33.1 8.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EEQ34543.1 - 4.1e-07 29.7 6.9 6.6e-07 29.1 6.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EEQ34543.1 - 4.2e-07 29.8 6.2 6.8e-07 29.1 6.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EEQ34543.1 - 8.4e-07 29.2 7.7 1.7e-06 28.2 7.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EEQ34543.1 - 6.3e-06 26.3 9.1 1.1e-05 25.5 9.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EEQ34543.1 - 0.0019 18.3 5.1 0.0034 17.5 5.1 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EEQ34543.1 - 0.0073 16.2 3.0 0.013 15.3 3.0 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EEQ34543.1 - 0.0086 16.1 3.1 0.015 15.3 3.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EEQ34543.1 - 0.021 14.7 4.2 0.038 13.8 4.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EEQ34543.1 - 0.19 11.5 7.7 0.4 10.5 7.7 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EEQ34543.1 - 0.22 11.2 4.7 0.4 10.3 4.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EEQ34543.1 - 0.3 10.9 3.9 0.76 9.6 3.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 EEQ34543.1 - 0.42 10.9 3.9 0.99 9.7 3.9 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain EXS PF03124.14 EEQ34544.1 - 1.8e-102 343.1 7.7 2e-102 342.9 7.7 1.0 1 0 0 1 1 1 1 EXS family DUF3431 PF11913.8 EEQ34545.1 - 1.4e-87 293.0 0.5 1.7e-87 292.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF2615 PF11027.8 EEQ34546.1 - 1.5 9.0 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) ATP-synt_S1 PF05827.12 EEQ34547.1 - 3.4e-05 23.7 0.0 7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.9 EEQ34548.1 - 1.1e-17 64.8 11.5 4.5e-13 49.8 1.3 3.7 2 2 2 4 4 4 2 Nucleolar protein 12 (25kDa) DUF4604 PF15377.6 EEQ34548.1 - 0.065 13.6 23.0 0.081 13.4 23.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Tropomyosin_1 PF12718.7 EEQ34549.1 - 2.8e-51 173.4 34.9 3.5e-51 173.1 34.9 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EEQ34549.1 - 1e-10 41.4 36.1 4e-06 26.4 17.8 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.9 EEQ34549.1 - 3.1e-05 24.1 24.0 7e-05 23.0 9.8 3.0 1 1 1 3 3 3 2 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 EEQ34549.1 - 0.00022 20.2 34.0 0.072 12.0 17.9 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EEQ34549.1 - 0.0013 18.8 34.8 0.0023 17.9 6.2 3.1 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 EEQ34549.1 - 0.0016 18.8 34.7 0.21 12.0 15.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EEQ34549.1 - 0.0023 17.9 17.3 0.0072 16.4 4.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) GAS PF13851.6 EEQ34549.1 - 0.0036 16.7 32.3 0.032 13.6 25.4 2.3 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding SlyX PF04102.12 EEQ34549.1 - 0.0099 16.5 26.8 0.017 15.7 8.4 3.2 1 1 2 3 3 3 2 SlyX Laminin_II PF06009.12 EEQ34549.1 - 0.01 15.9 8.1 0.01 15.9 8.1 2.1 1 1 1 2 2 2 0 Laminin Domain II ATG16 PF08614.11 EEQ34549.1 - 0.017 15.3 34.1 0.78 9.9 25.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 EEQ34549.1 - 0.019 15.0 38.8 0.024 14.7 17.8 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain ERM PF00769.19 EEQ34549.1 - 0.034 14.0 40.8 0.17 11.7 19.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family JIP_LZII PF16471.5 EEQ34549.1 - 0.04 14.1 4.4 0.04 14.1 4.4 4.1 2 1 3 5 5 5 0 JNK-interacting protein leucine zipper II MS_channel PF00924.18 EEQ34549.1 - 0.041 13.4 3.3 0.05 13.2 3.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel CEP63 PF17045.5 EEQ34549.1 - 0.042 13.7 29.0 0.29 11.0 29.0 1.9 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa Sipho_Gp157 PF05565.11 EEQ34549.1 - 0.063 13.3 24.8 0.061 13.3 7.4 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 FlaC_arch PF05377.11 EEQ34549.1 - 0.1 13.0 20.3 0.6 10.5 3.9 4.1 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) KELK PF15796.5 EEQ34549.1 - 0.16 12.4 32.3 3.6 8.1 8.1 3.4 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MAD PF05557.13 EEQ34549.1 - 0.16 10.3 33.1 0.47 8.7 33.1 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein ADIP PF11559.8 EEQ34549.1 - 0.17 11.9 33.4 1.9 8.6 1.4 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 EEQ34549.1 - 0.33 11.2 35.5 0.27 11.4 11.7 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Filament PF00038.21 EEQ34549.1 - 0.34 10.5 29.9 0.85 9.1 17.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein Uso1_p115_C PF04871.13 EEQ34549.1 - 0.4 11.1 36.1 0.35 11.3 16.3 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CLZ PF16526.5 EEQ34549.1 - 0.49 10.8 25.6 0.28 11.6 2.7 3.4 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 EEQ34549.1 - 0.49 9.7 30.5 0.13 11.5 9.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 EEQ34549.1 - 0.6 10.5 22.7 1.2 9.5 0.9 3.3 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 EEQ34549.1 - 0.68 9.7 28.8 0.18 11.6 10.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HOOK PF05622.12 EEQ34549.1 - 0.69 8.0 29.5 1.6 6.8 29.6 1.4 1 1 0 1 1 1 0 HOOK protein Fez1 PF06818.15 EEQ34549.1 - 0.91 9.9 29.9 0.58 10.6 24.3 1.9 1 1 1 2 2 2 0 Fez1 AAA_13 PF13166.6 EEQ34549.1 - 0.99 8.0 27.8 3.4 6.2 27.8 2.0 1 1 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.8 EEQ34549.1 - 1 9.4 36.6 0.12 12.4 13.1 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding KxDL PF10241.9 EEQ34549.1 - 1.2 9.5 22.0 0.39 11.0 1.0 3.8 1 1 3 4 4 4 0 Uncharacterized conserved protein DUF5082 PF16888.5 EEQ34549.1 - 1.3 9.4 23.1 3.8 7.8 0.6 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) bZIP_1 PF00170.21 EEQ34549.1 - 1.6 8.9 25.8 2.4 8.3 0.7 3.9 2 1 2 4 4 4 0 bZIP transcription factor HMMR_N PF15905.5 EEQ34549.1 - 1.7 8.1 32.2 17 4.8 32.2 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 EEQ34549.1 - 1.7 8.9 32.7 11 6.2 11.1 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 EEQ34549.1 - 2 6.9 10.0 2.2 6.7 10.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cep57_MT_bd PF06657.13 EEQ34549.1 - 2.2 8.8 21.7 0.08 13.4 4.6 3.7 1 1 2 3 3 2 0 Centrosome microtubule-binding domain of Cep57 BST2 PF16716.5 EEQ34549.1 - 2.2 8.9 29.3 2 9.0 11.4 3.3 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 Med9 PF07544.13 EEQ34549.1 - 2.7 8.2 28.7 0.31 11.1 4.9 3.3 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.9 EEQ34549.1 - 2.9 6.9 28.1 2.7 7.0 11.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Herpes_UL6 PF01763.16 EEQ34549.1 - 4.3 5.7 15.6 1.8 7.0 8.9 2.1 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF3584 PF12128.8 EEQ34549.1 - 4.5 4.7 30.3 13 3.2 13.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4472 PF14739.6 EEQ34549.1 - 4.7 8.0 28.9 28 5.5 10.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DivIC PF04977.15 EEQ34549.1 - 5.5 6.8 34.6 0.8 9.5 1.4 4.5 1 1 3 4 4 4 0 Septum formation initiator UPF0242 PF06785.11 EEQ34549.1 - 5.9 7.0 33.2 8.2 6.5 12.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YjcZ PF13990.6 EEQ34549.1 - 6.3 6.1 12.9 8.3 5.7 12.5 1.4 1 1 0 1 1 1 0 YjcZ-like protein XhlA PF10779.9 EEQ34549.1 - 6.4 7.1 25.6 2.8 8.2 2.0 4.1 1 1 2 4 4 4 0 Haemolysin XhlA DUF16 PF01519.16 EEQ34549.1 - 6.5 7.3 22.2 3.4 8.2 6.7 2.7 1 1 1 2 2 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EEQ34549.1 - 6.9 6.9 21.4 28 4.9 1.8 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PI3K_P85_iSH2 PF16454.5 EEQ34549.1 - 6.9 6.2 28.5 18 4.9 22.2 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5320 PF17253.2 EEQ34549.1 - 6.9 7.8 22.1 11 7.1 4.4 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5320) FapA PF03961.13 EEQ34549.1 - 7.2 5.1 27.2 0.2 10.2 9.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A PRKG1_interact PF15898.5 EEQ34549.1 - 7.4 7.5 32.4 31 5.6 14.6 2.9 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Macoilin PF09726.9 EEQ34549.1 - 7.9 4.9 27.9 11 4.4 27.9 1.1 1 0 0 1 1 1 0 Macoilin family FAD-SLDH PF12318.8 EEQ34549.1 - 8 6.5 8.5 6.8 6.7 3.1 2.2 1 1 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Swi5 PF07061.11 EEQ34549.1 - 9.5 6.4 30.6 2.2 8.4 1.5 4.1 1 1 3 4 4 4 0 Swi5 PspB PF06667.12 EEQ34549.1 - 9.7 6.3 18.0 1.4 9.0 4.4 3.4 1 1 2 3 3 3 0 Phage shock protein B CMAS PF02353.20 EEQ34551.1 - 1.7e-60 204.6 0.0 2.2e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EEQ34551.1 - 6e-10 39.2 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ34551.1 - 3.9e-09 37.1 0.0 7.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ34551.1 - 3e-08 34.2 0.0 7.6e-08 32.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ34551.1 - 0.0011 19.6 0.0 0.0022 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EEQ34551.1 - 0.018 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 N6_N4_Mtase PF01555.18 EEQ34551.1 - 0.035 13.8 0.0 6.5 6.4 0.0 2.4 2 0 0 2 2 2 0 DNA methylase FtsJ PF01728.19 EEQ34551.1 - 0.038 14.1 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 EEQ34551.1 - 0.044 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 EEQ34551.1 - 0.055 13.2 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EEQ34551.1 - 0.091 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2273 PF10031.9 EEQ34551.1 - 1 9.5 3.1 4 7.5 0.9 2.3 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) AMP-binding PF00501.28 EEQ34552.1 - 2.1e-71 240.7 0.0 2.8e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ34552.1 - 1.8e-16 60.9 0.0 4.3e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EEQ34560.1 - 1.6e-25 89.8 34.9 1.4e-14 53.8 11.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 EEQ34560.1 - 0.2 9.9 15.5 0.037 12.3 1.3 3.3 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family APH PF01636.23 EEQ34561.1 - 4.8e-12 46.3 0.0 1.1e-11 45.1 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EGF_CA PF07645.15 EEQ34563.1 - 2.9e-06 27.4 6.1 2.9e-06 27.4 6.1 1.7 2 0 0 2 2 2 1 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 EEQ34563.1 - 0.00093 19.4 1.6 0.00093 19.4 1.6 1.9 2 0 0 2 2 2 1 Pvs28 EGF domain FXa_inhibition PF14670.6 EEQ34563.1 - 0.0028 17.9 3.4 0.0028 17.9 3.4 2.6 2 2 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 EEQ34563.1 - 0.0028 17.8 5.3 0.0028 17.8 5.3 2.3 2 1 0 2 2 2 1 EGF domain cEGF PF12662.7 EEQ34563.1 - 0.0035 17.2 0.1 0.0035 17.2 0.1 2.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.27 EEQ34563.1 - 0.0071 16.6 5.0 0.0071 16.6 5.0 2.0 2 1 0 2 2 2 1 EGF-like domain MCM PF00493.23 EEQ34565.1 - 3.5e-103 343.5 0.0 5.6e-103 342.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEQ34565.1 - 3.6e-31 107.6 0.0 6.8e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEQ34565.1 - 2.6e-21 75.8 0.4 7.1e-21 74.4 0.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ34565.1 - 2.1e-17 63.6 0.8 5.4e-17 62.3 0.8 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ34565.1 - 3.9e-07 29.7 0.0 5.5e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ34565.1 - 2e-05 24.6 0.0 6e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EEQ34565.1 - 0.05 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 EEQ34565.1 - 0.063 13.1 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3053 PF11254.8 EEQ34565.1 - 0.2 11.2 1.6 0.26 10.8 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) AAA PF00004.29 EEQ34566.1 - 1.5e-54 184.0 0.0 3.6e-43 147.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EEQ34566.1 - 2.6e-30 104.6 0.7 7e-30 103.3 0.7 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EEQ34566.1 - 8.1e-15 54.4 0.1 3e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EEQ34566.1 - 9.8e-08 32.6 6.5 0.0023 18.3 0.1 4.2 3 2 1 4 4 3 2 AAA ATPase domain AAA_2 PF07724.14 EEQ34566.1 - 6.9e-07 29.5 0.0 0.032 14.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 EEQ34566.1 - 1.2e-06 28.6 1.1 0.00045 20.2 0.0 3.5 4 0 0 4 4 3 1 NACHT domain RuvB_N PF05496.12 EEQ34566.1 - 1.4e-05 24.9 0.0 0.016 14.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EEQ34566.1 - 5.7e-05 23.1 0.0 0.12 12.4 0.0 2.8 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EEQ34566.1 - 7e-05 23.1 1.0 0.8 10.0 0.1 3.6 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EEQ34566.1 - 9.2e-05 22.2 0.0 0.063 13.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 EEQ34566.1 - 0.00036 20.5 0.1 1 9.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EEQ34566.1 - 0.00096 18.5 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 EEQ34566.1 - 0.00099 19.3 0.0 0.26 11.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EEQ34566.1 - 0.0011 19.0 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EEQ34566.1 - 0.0011 19.5 0.0 1.5 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EEQ34566.1 - 0.0034 16.7 0.0 0.66 9.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 EEQ34566.1 - 0.0038 16.8 0.6 5.9 6.4 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.6 EEQ34566.1 - 0.01 16.1 0.0 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EEQ34566.1 - 0.011 16.1 0.0 8.1 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 EEQ34566.1 - 0.019 14.3 0.1 0.97 8.8 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EEQ34566.1 - 0.02 13.9 0.1 0.055 12.5 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 EEQ34566.1 - 0.026 15.0 0.1 5.7 7.4 0.1 2.7 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 EEQ34566.1 - 0.04 13.4 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 EEQ34566.1 - 0.043 13.1 0.2 0.22 10.7 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain ATPase PF06745.13 EEQ34566.1 - 0.098 12.0 0.1 14 4.9 0.0 2.4 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.18 EEQ34566.1 - 0.1 12.3 0.1 0.59 9.8 0.0 2.3 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 EEQ34566.1 - 0.12 12.3 0.1 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma54_activ_2 PF14532.6 EEQ34566.1 - 0.15 12.2 0.0 7.9 6.6 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 EEQ34566.1 - 0.18 11.5 0.0 7.3 6.3 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 EEQ34566.1 - 0.31 11.5 1.6 3.1 8.2 0.1 2.9 4 0 0 4 4 2 0 AAA domain HisG PF01634.18 EEQ34567.1 - 5e-55 185.8 0.0 7.2e-55 185.3 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EEQ34567.1 - 4.1e-28 97.3 0.1 8.8e-28 96.3 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EEQ34567.1 - 0.00078 19.4 0.1 0.0022 18.0 0.1 1.7 1 1 0 1 1 1 1 NMT1/THI5 like Ribosomal_S28e PF01200.18 EEQ34568.1 - 4.4e-33 113.1 0.4 4.9e-33 112.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.21 EEQ34569.1 - 3.9e-73 245.5 0.1 7.4e-73 244.6 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EEQ34569.1 - 2.2e-34 119.4 0.5 6.4e-34 117.9 0.5 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EEQ34569.1 - 1.3e-27 96.2 0.2 3.7e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 EEQ34569.1 - 5.9e-10 39.6 0.0 2.3e-09 37.6 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EEQ34569.1 - 5.3e-05 23.5 0.4 0.00013 22.2 0.4 1.7 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 EEQ34569.1 - 0.029 14.4 0.0 0.089 12.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Prenyltrans PF00432.21 EEQ34571.1 - 4e-47 157.6 10.6 5.5e-11 42.0 0.0 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EEQ34571.1 - 9.9e-06 24.9 0.0 0.031 13.4 0.0 3.2 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EEQ34571.1 - 0.0018 17.5 0.3 0.17 11.0 0.0 2.8 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain RhoGAP PF00620.27 EEQ34573.1 - 2.3e-16 60.0 0.0 4.1e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.12 EEQ34574.1 - 2.9e-55 186.6 2.4 2.9e-55 186.6 2.4 1.3 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Ribosomal_L41 PF05162.13 EEQ34574.1 - 0.41 10.8 11.0 0.072 13.2 5.7 2.4 2 0 0 2 2 2 0 Ribosomal protein L41 DAP3 PF10236.9 EEQ34575.1 - 1.6e-86 290.3 0.0 2.4e-86 289.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 PrpF PF04303.13 EEQ34578.1 - 1.7e-102 343.2 0.2 2e-102 343.0 0.2 1.0 1 0 0 1 1 1 1 PrpF protein Peptidase_C48 PF02902.19 EEQ34579.1 - 1.2e-15 57.9 1.7 5.7e-15 55.7 0.5 2.6 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 EEQ34579.1 - 0.21 11.7 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) RhoGEF PF00621.20 EEQ34580.1 - 1.1e-35 123.6 0.0 2.4e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain Telomerase_RBD PF12009.8 EEQ34581.1 - 7.5e-48 162.0 0.0 1.6e-47 161.0 0.0 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EEQ34581.1 - 1.1e-11 44.7 0.0 1.5e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Aldo_ket_red PF00248.21 EEQ34582.1 - 9.3e-34 117.0 0.0 1.9e-33 116.0 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Sulfotransfer_4 PF17784.1 EEQ34583.1 - 1.6e-56 191.5 0.0 2e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EEQ34583.1 - 0.027 14.9 0.0 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Sulfotransferase family IDO PF01231.18 EEQ34584.1 - 6.5e-111 371.2 0.0 1.1e-108 363.9 0.0 2.2 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 EEQ34584.1 - 0.0079 15.0 0.0 0.038 12.7 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1864) Pkinase PF00069.25 EEQ34585.1 - 7.2e-20 71.4 0.0 9e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34585.1 - 2.3e-12 46.7 0.0 3.1e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ34585.1 - 0.00059 19.2 0.0 0.00084 18.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ34585.1 - 0.016 14.0 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pox_G9-A16 PF03003.16 EEQ34585.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 Kdo PF06293.14 EEQ34585.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 EEQ34585.1 - 0.22 11.2 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 RabGAP-TBC PF00566.18 EEQ34586.1 - 1.1e-19 71.0 0.0 2.2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EEQ34586.1 - 3.8e-08 32.1 0.2 7.6e-08 31.1 0.2 1.5 1 0 0 1 1 1 1 SBE2, cell-wall formation NINJA_B PF16136.5 EEQ34586.1 - 1.9 8.9 9.3 0.98 9.8 5.0 2.9 3 0 0 3 3 3 0 Putative nuclear localisation signal Proteasome PF00227.26 EEQ34587.1 - 5.2e-44 150.0 0.2 6.6e-44 149.7 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 EEQ34588.1 - 1.4e-36 126.3 1.8 8.8e-24 84.7 0.4 3.7 2 1 2 4 4 4 2 Cyclin SUIM_assoc PF16619.5 EEQ34588.1 - 0.26 11.4 16.4 3.7 7.7 1.8 4.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Hydrolase_4 PF12146.8 EEQ34589.1 - 2.9e-18 66.0 0.0 3e-13 49.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ34589.1 - 3.2e-12 46.6 0.0 8.8e-10 38.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ34589.1 - 2.4e-05 25.0 0.0 3.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EEQ34589.1 - 3.5e-05 23.4 0.0 0.0004 19.9 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EEQ34589.1 - 5.1e-05 22.1 0.3 0.044 12.5 0.1 2.9 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 EEQ34589.1 - 9e-05 22.1 0.0 0.0022 17.6 0.0 2.5 1 1 1 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 EEQ34589.1 - 0.0002 21.4 0.0 0.018 15.0 0.0 2.3 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 EEQ34589.1 - 0.00022 21.0 0.0 0.00067 19.4 0.0 1.7 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EEQ34589.1 - 0.0036 17.2 0.1 0.009 15.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EEQ34589.1 - 0.0043 16.8 0.2 0.024 14.4 0.2 2.0 1 1 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 EEQ34589.1 - 0.015 14.8 0.0 0.044 13.3 0.0 1.6 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 EEQ34589.1 - 0.017 14.9 0.3 1.1 9.0 0.1 2.6 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EEQ34589.1 - 0.024 14.7 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 EEQ34589.1 - 0.025 14.4 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF818 PF05677.12 EEQ34589.1 - 0.059 12.3 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF2974 PF11187.8 EEQ34589.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 EEQ34589.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 EEQ34589.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 EEQ34589.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase ATP11 PF06644.11 EEQ34590.1 - 1.2e-99 333.5 0.0 1.4e-99 333.3 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Scytalone_dh PF02982.14 EEQ34590.1 - 0.052 13.3 0.1 0.084 12.7 0.1 1.2 1 0 0 1 1 1 0 Scytalone dehydratase FAM60A PF15396.6 EEQ34590.1 - 0.15 12.0 1.6 0.2 11.6 1.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Glyco_hydro_3 PF00933.21 EEQ34591.1 - 4.5e-81 272.7 0.0 6.2e-81 272.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 EEQ34591.1 - 1.9e-17 63.5 0.0 6.3e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ34591.1 - 1.4e-16 60.7 0.0 1.9e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ34591.1 - 3e-13 49.8 0.0 3.5e-07 30.2 0.0 3.0 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEQ34591.1 - 4.4e-06 26.8 0.0 0.047 13.8 0.0 3.4 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EEQ34591.1 - 7e-06 26.1 0.1 0.0034 17.5 0.0 3.2 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase Glyco_hydro_3_C PF01915.22 EEQ34591.1 - 1.9e-05 24.7 0.0 0.00014 21.9 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain FR47 PF08445.10 EEQ34591.1 - 0.0017 18.3 0.0 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 FR47-like protein PanZ PF12568.8 EEQ34591.1 - 0.0074 16.0 0.0 0.094 12.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_6 PF13480.7 EEQ34591.1 - 0.078 13.1 0.0 18 5.4 0.0 3.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 EEQ34593.1 - 2.2e-15 56.8 0.0 8.3e-09 35.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34593.1 - 6.9e-05 22.3 0.1 0.16 11.2 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase PAGK PF15284.6 EEQ34593.1 - 0.066 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Phage-encoded virulence factor Aldo_ket_red PF00248.21 EEQ34594.1 - 1.8e-47 162.0 0.0 3.3e-47 161.1 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_M14 PF00246.24 EEQ34595.1 - 2.1e-14 54.0 0.0 3.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EEQ34595.1 - 0.017 14.2 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 EEQ34595.1 - 0.077 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Peptidase_M36 PF02128.15 EEQ34596.1 - 1.4e-147 491.8 4.0 2e-147 491.3 4.0 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EEQ34596.1 - 3.9e-11 42.6 4.0 2.3e-10 40.1 4.0 2.2 1 1 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif adh_short PF00106.25 EEQ34597.1 - 5.2e-11 42.4 0.0 8.8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ34597.1 - 1.4e-07 31.6 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EEQ34597.1 - 1.8e-06 27.7 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Tropomyosin PF00261.20 EEQ34598.1 - 0.0035 16.7 4.4 0.0067 15.8 4.4 1.4 1 0 0 1 1 1 1 Tropomyosin APH PF01636.23 EEQ34598.1 - 0.0045 17.0 0.9 0.015 15.2 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Alanine_zipper PF11839.8 EEQ34598.1 - 0.0061 16.9 1.3 0.012 15.9 1.3 1.4 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein HSDR_N_2 PF13588.6 EEQ34598.1 - 0.025 14.6 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Pkinase PF00069.25 EEQ34598.1 - 0.097 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain XhlA PF10779.9 EEQ34598.1 - 0.15 12.3 1.2 0.33 11.2 1.2 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Sugarporin_N PF11471.8 EEQ34598.1 - 3.1 7.8 7.7 7.7 6.6 7.7 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Beta_elim_lyase PF01212.21 EEQ34599.1 - 8.8e-56 189.3 0.0 1.1e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EEQ34599.1 - 0.053 12.0 0.0 0.11 11.0 0.0 1.4 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GFA PF04828.14 EEQ34600.1 - 4e-16 59.1 0.4 5.2e-16 58.8 0.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme HNH_2 PF13391.6 EEQ34601.1 - 3.3e-14 52.8 0.0 6.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease FAD_binding_7 PF03441.14 EEQ34602.1 - 1e-73 247.1 0.1 2.1e-73 246.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EEQ34602.1 - 8.4e-39 133.2 0.3 1.8e-38 132.1 0.1 1.6 2 0 0 2 2 2 1 DNA photolyase Guanylin PF02058.15 EEQ34602.1 - 0.018 15.5 0.1 3.4 8.2 0.0 2.7 1 1 1 2 2 2 0 Guanylin precursor DUF1653 PF07866.11 EEQ34604.1 - 0.016 15.5 0.7 0.066 13.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1653) Glyco_hydro_18 PF00704.28 EEQ34605.1 - 1.4e-16 61.2 0.3 2.5e-16 60.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EEQ34606.1 - 9.4e-06 25.6 0.1 0.0016 18.5 0.0 2.8 2 0 0 2 2 2 2 LysM domain Ski_Sno PF02437.17 EEQ34606.1 - 0.044 13.5 1.0 0.13 12.0 0.4 2.0 2 0 0 2 2 2 0 SKI/SNO/DAC family UPF0203 PF05254.12 EEQ34606.1 - 0.43 10.9 7.3 0.04 14.2 1.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Bromo_TP PF07524.13 EEQ34607.1 - 1.8e-10 40.6 0.0 3.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EEQ34607.1 - 0.018 15.1 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AstB PF04996.12 EEQ34607.1 - 0.037 12.7 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase TAFII55_N PF04658.13 EEQ34608.1 - 4.5e-52 176.0 0.0 9.4e-52 175.0 0.0 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region NinE PF05322.11 EEQ34608.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 NINE Protein BRO1 PF03097.18 EEQ34609.1 - 5.1e-12 45.3 0.2 7.3e-12 44.8 0.2 1.1 1 0 0 1 1 1 1 BRO1-like domain NDUFB10 PF10249.9 EEQ34610.1 - 0.0068 16.9 0.0 0.0076 16.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Glyco_transf_34 PF05637.12 EEQ34611.1 - 6.8e-64 215.9 0.0 9.7e-64 215.3 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Peptidase_M28 PF04389.17 EEQ34612.1 - 2e-21 76.6 0.0 3.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 EEQ34612.1 - 2.6e-21 76.0 0.0 4.1e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 EEQ34612.1 - 1.3e-09 38.0 0.5 5e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EEQ34612.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EEQ34612.1 - 0.074 12.5 0.0 4 6.8 0.0 2.3 2 0 0 2 2 2 0 Nicastrin Propeptide_C1 PF08127.13 EEQ34612.1 - 0.2 11.5 0.2 7.9 6.5 0.1 2.8 2 0 0 2 2 2 0 Peptidase family C1 propeptide Pkinase PF00069.25 EEQ34613.1 - 1.2e-63 214.9 0.0 3e-63 213.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34613.1 - 9.7e-31 107.0 0.0 1.7e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EEQ34613.1 - 2.4e-09 37.4 0.1 2.7e-08 34.1 0.0 2.7 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 EEQ34613.1 - 0.00011 22.5 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 EEQ34613.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CN_hydrolase PF00795.22 EEQ34614.1 - 5e-44 150.6 0.0 6.3e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Beta_elim_lyase PF01212.21 EEQ34615.1 - 6.1e-65 219.4 0.0 7.5e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EEQ34615.1 - 0.15 10.6 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme KIAA1430 PF13879.6 EEQ34616.1 - 7.9 7.3 10.2 0.094 13.5 0.8 2.6 3 0 0 3 3 3 0 KIAA1430 homologue RNase_T PF00929.24 EEQ34617.1 - 6.5e-08 33.3 0.0 1.6e-07 32.0 0.0 1.7 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EEQ34617.1 - 0.21 11.3 0.0 0.43 10.3 0.0 1.5 1 1 0 1 1 1 0 3'-5' exonuclease OPT PF03169.15 EEQ34618.1 - 1e-162 543.0 48.7 3e-85 287.1 22.0 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Tweety PF04906.13 EEQ34618.1 - 0.38 9.4 2.3 0.61 8.7 2.3 1.2 1 0 0 1 1 1 0 Tweety DUF4191 PF13829.6 EEQ34618.1 - 2 7.7 5.4 0.22 10.8 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Bac_export_3 PF01313.19 EEQ34618.1 - 2.4 8.2 11.2 0.53 10.2 1.8 3.4 3 0 0 3 3 3 0 Bacterial export proteins, family 3 Glutaredoxin PF00462.24 EEQ34619.1 - 4.6e-18 65.2 0.0 1.2e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EEQ34619.1 - 6.4e-12 45.4 0.0 2e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EEQ34619.1 - 0.0078 16.5 0.0 0.36 11.2 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 EEQ34619.1 - 0.07 12.5 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EEQ34619.1 - 0.11 13.0 0.0 0.53 10.8 0.0 2.1 2 2 1 3 3 3 0 Thioredoxin-like domain TauD PF02668.16 EEQ34620.1 - 6.4e-45 154.0 0.0 9.3e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EEQ34620.1 - 4.1e-06 27.3 0.1 4.7e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 EEQ34620.1 - 0.026 13.7 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 CsiD Mito_carr PF00153.27 EEQ34621.1 - 7.2e-65 215.0 1.6 1.9e-20 72.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ34621.1 - 0.077 12.1 2.0 1.4 8.0 0.0 3.1 4 0 0 4 4 4 0 Gammaproteobacterial serine protease HMD PF03201.16 EEQ34621.1 - 0.087 13.1 0.0 1.3 9.3 0.0 2.5 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Tubulin PF00091.25 EEQ34622.1 - 5.2e-65 219.4 0.0 6.7e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EEQ34622.1 - 2.7e-44 150.3 0.0 4.2e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EEQ34622.1 - 0.00037 20.2 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.18 EEQ34623.1 - 6.4e-24 84.6 3.0 1.3e-23 83.6 3.0 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 EEQ34623.1 - 1.1e-05 24.7 0.0 2.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EEQ34623.1 - 0.00027 20.3 0.2 0.00061 19.2 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EEQ34623.1 - 0.00082 19.1 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EEQ34623.1 - 0.0057 17.1 0.3 0.015 15.8 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair DUF3671 PF12420.8 EEQ34623.1 - 2.7 8.1 6.5 2.7 8.1 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function PAG PF15347.6 EEQ34626.1 - 0.012 14.6 0.7 0.013 14.6 0.7 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched RE_AccI PF09545.10 EEQ34626.1 - 0.034 13.1 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease SNF2_N PF00176.23 EEQ34627.1 - 1.7e-24 86.2 0.0 2.8e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EEQ34627.1 - 1e-08 35.4 0.0 2.7e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 EEQ34627.1 - 0.58 9.0 1.7 1.2 7.9 0.1 2.1 2 1 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 PDR_CDR PF06422.12 EEQ34630.1 - 5.8e-37 125.5 0.1 3.7e-32 110.1 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 EEQ34630.1 - 8.7e-37 126.7 0.3 4.5e-17 62.9 0.0 3.1 4 0 0 4 4 3 2 ABC transporter ABC2_membrane PF01061.24 EEQ34630.1 - 1.1e-27 96.8 29.6 1.4e-11 44.2 5.9 4.7 3 2 1 4 4 4 3 ABC-2 type transporter ABC_trans_N PF14510.6 EEQ34630.1 - 8.1e-19 68.0 0.0 1.9e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EEQ34630.1 - 2e-07 31.6 0.0 0.0011 19.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EEQ34630.1 - 2.7e-06 27.6 0.1 0.00028 21.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EEQ34630.1 - 6.5e-06 26.1 0.2 0.0013 18.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EEQ34630.1 - 8.1e-06 25.5 0.1 0.00014 21.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ34630.1 - 3e-05 24.6 0.0 0.009 16.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EEQ34630.1 - 0.00055 19.6 2.3 0.039 13.7 0.1 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EEQ34630.1 - 0.0019 18.1 0.0 1.7 8.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EEQ34630.1 - 0.0028 17.9 0.4 1.4 9.2 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEQ34630.1 - 0.0079 15.9 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EEQ34630.1 - 0.013 15.1 1.1 0.26 10.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EEQ34630.1 - 0.023 14.8 0.2 9.5 6.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 EEQ34630.1 - 0.024 14.1 0.0 1.9 7.9 0.0 3.0 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EEQ34630.1 - 0.058 13.3 2.1 3.5 7.5 0.2 2.9 3 0 0 3 3 3 0 NACHT domain Rad17 PF03215.15 EEQ34630.1 - 0.066 13.1 0.0 8.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 EEQ34630.1 - 0.11 12.7 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EEQ34630.1 - 0.11 12.2 0.0 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EEQ34630.1 - 0.19 12.2 0.1 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EEQ34630.1 - 0.2 11.7 0.5 2.9 7.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) zf-C2H2 PF00096.26 EEQ34633.1 - 0.85 10.2 15.3 4.7 7.9 0.3 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ34633.1 - 0.91 10.5 13.7 0.42 11.6 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger Ribul_P_3_epim PF00834.19 EEQ34634.1 - 4.2e-61 205.8 0.0 3.4e-60 202.9 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Melibiase PF02065.18 EEQ34634.1 - 0.13 11.2 0.0 9.8 5.0 0.0 2.2 2 0 0 2 2 2 0 Melibiase SH3BGR PF04908.15 EEQ34635.1 - 0.00066 19.8 0.4 0.0052 16.9 0.0 2.5 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 EEQ34635.1 - 0.19 12.0 0.0 0.53 10.6 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin zf-BED PF02892.15 EEQ34636.1 - 0.00083 19.3 5.5 0.28 11.2 0.3 2.7 2 0 0 2 2 2 2 BED zinc finger RAP1 PF07218.11 EEQ34636.1 - 4 5.6 6.2 7 4.8 6.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Methyltransf_11 PF08241.12 EEQ34637.1 - 3.1e-06 27.8 0.0 6.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ34637.1 - 0.032 14.9 0.0 0.09 13.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 EEQ34638.1 - 8.9e-18 63.8 1.0 1.1e-17 63.4 1.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EEQ34638.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DUF402 PF04167.13 EEQ34638.1 - 0.085 13.1 0.4 0.12 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF402) DRMBL PF07522.14 EEQ34639.1 - 3.2e-35 120.6 0.0 6.2e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EEQ34639.1 - 4.8e-06 26.2 0.0 9.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EEQ34639.1 - 0.027 14.5 0.2 0.051 13.6 0.2 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily FAD_binding_4 PF01565.23 EEQ34640.1 - 6.6e-19 68.0 0.8 1e-18 67.4 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Nbl1_Borealin_N PF10444.9 EEQ34641.1 - 5.7e-20 70.7 4.6 1.4e-19 69.5 4.6 1.7 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 EEQ34642.1 - 2.6e-18 66.6 0.0 6.4e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EEQ34642.1 - 5.1e-05 23.6 0.0 7.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EEQ34642.1 - 0.0044 16.9 0.0 0.0066 16.3 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like Phage_Gp23 PF10669.9 EEQ34642.1 - 0.035 14.4 2.1 0.081 13.3 2.1 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) UIM PF02809.20 EEQ34642.1 - 0.042 13.8 0.3 0.042 13.8 0.3 2.0 2 0 0 2 2 2 0 Ubiquitin interaction motif Val_tRNA-synt_C PF10458.9 EEQ34642.1 - 0.081 13.2 5.4 0.2 12.0 5.4 1.6 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Casc1_N PF15927.5 EEQ34642.1 - 0.18 11.5 3.1 0.42 10.3 3.1 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus APC_u15 PF16636.5 EEQ34642.1 - 1.3 9.5 7.3 0.74 10.3 5.0 1.7 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Sybindin PF04099.12 EEQ34643.1 - 3.4e-46 156.7 0.0 4.5e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EEQ34643.1 - 1.5e-06 28.4 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region UQ_con PF00179.26 EEQ34644.1 - 4.2e-24 84.8 0.0 2.3e-08 33.8 0.0 3.3 2 1 1 3 3 3 3 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ34644.1 - 2.1e-06 27.5 0.0 0.00022 20.9 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic E2 family B DUF2300 PF10062.9 EEQ34645.1 - 0.045 13.8 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) ketoacyl-synt PF00109.26 EEQ34647.1 - 3.7e-75 252.8 0.2 6.2e-75 252.0 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EEQ34647.1 - 7.7e-38 129.1 0.0 1.7e-37 128.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EEQ34647.1 - 5.6e-27 93.9 7.1 8.8e-14 51.6 0.7 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Acyl_transf_1 PF00698.21 EEQ34647.1 - 3.6e-22 79.3 0.0 7.2e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EEQ34647.1 - 7.2e-17 61.6 0.0 1.5e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_3 PF07859.13 EEQ34647.1 - 1.9e-10 41.0 0.0 8.9e-09 35.5 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold SAT PF16073.5 EEQ34647.1 - 2.5e-09 37.2 1.1 4.2e-07 29.9 0.0 3.2 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Peptidase_S9 PF00326.21 EEQ34647.1 - 5.4e-08 32.6 0.0 5.5e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thiolase_N PF00108.23 EEQ34647.1 - 4.1e-07 29.6 1.1 7.5e-07 28.8 1.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EEQ34647.1 - 3e-05 24.4 0.0 8.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 EEQ34647.1 - 8.5e-05 23.3 0.8 0.00036 21.2 0.3 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 EEQ34647.1 - 0.0042 16.7 0.0 0.055 13.0 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EEQ34647.1 - 0.019 14.3 0.0 0.048 12.9 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EEQ34647.1 - 0.084 12.7 0.0 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 EEQ34647.1 - 0.13 11.9 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 EEQ34647.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family FGE-sulfatase PF03781.16 EEQ34648.1 - 1e-30 107.2 0.1 1.5e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EEQ34648.1 - 9.4e-07 29.4 0.5 2.3e-06 28.2 0.5 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.6 EEQ34648.1 - 2.8e-06 27.9 0.0 0.00011 22.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ34648.1 - 0.0025 18.4 0.0 0.035 14.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ34648.1 - 0.043 13.6 0.0 4.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 EEQ34648.1 - 0.17 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Gln-synt_C PF00120.24 EEQ34649.1 - 2.1e-50 171.7 0.0 1.4e-49 169.0 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain IDO PF01231.18 EEQ34650.1 - 3.8e-34 118.2 0.0 5.4e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase APH PF01636.23 EEQ34651.1 - 1.8e-12 47.7 0.0 7.9e-12 45.6 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family HalX PF08663.10 EEQ34651.1 - 0.086 13.2 2.4 0.19 12.1 2.4 1.5 1 0 0 1 1 1 0 HalX domain KfrA_N PF11740.8 EEQ34651.1 - 2.7 8.7 5.9 5 7.8 5.9 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term 3Beta_HSD PF01073.19 EEQ34652.1 - 2.4e-45 154.7 0.0 1.1e-40 139.5 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EEQ34652.1 - 8.1e-16 58.2 0.3 5.2e-15 55.6 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EEQ34652.1 - 1.6e-10 40.6 0.0 2e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EEQ34652.1 - 2.1e-10 40.6 0.0 4.4e-05 23.0 0.0 3.3 3 0 0 3 3 3 3 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EEQ34652.1 - 0.003 16.7 0.1 0.0082 15.3 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EEQ34652.1 - 0.019 14.9 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding Pkinase PF00069.25 EEQ34653.1 - 1.5e-59 201.6 0.0 3.9e-39 134.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34653.1 - 7.3e-29 100.8 0.0 5.4e-21 75.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EEQ34653.1 - 1.4e-12 47.7 0.0 2.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EEQ34653.1 - 6.7e-08 32.2 0.0 1.2e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EEQ34653.1 - 0.00013 21.9 0.1 0.0055 16.7 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ34653.1 - 0.003 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 EEQ34653.1 - 0.0056 16.9 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 EEQ34653.1 - 0.017 14.1 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain PAS PF00989.25 EEQ34653.1 - 0.034 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold RIO1 PF01163.22 EEQ34653.1 - 0.098 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family PAS_4 PF08448.10 EEQ34653.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 EEQ34653.1 - 0.15 11.1 0.1 0.3 10.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 eIF-3_zeta PF05091.12 EEQ34654.1 - 4.2e-200 666.1 0.0 5e-200 665.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_1 PF00170.21 EEQ34655.1 - 0.018 15.1 14.1 0.19 11.8 14.1 2.4 1 1 0 1 1 1 0 bZIP transcription factor Med9 PF07544.13 EEQ34655.1 - 0.019 15.0 4.5 0.084 13.0 4.4 2.1 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 UPF0242 PF06785.11 EEQ34655.1 - 1.3 9.0 6.9 3.8 7.6 6.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TEX13 PF15186.6 EEQ34655.1 - 1.9 8.2 5.5 3.2 7.4 5.5 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family bZIP_2 PF07716.15 EEQ34655.1 - 2.2 8.5 14.1 0.12 12.5 4.5 2.5 2 0 0 2 2 2 0 Basic region leucine zipper F-box-like PF12937.7 EEQ34656.1 - 0.0043 16.9 0.1 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 EEQ34656.1 - 0.041 13.8 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 F-box DUF3552 PF12072.8 EEQ34658.1 - 0.052 13.0 6.9 0.074 12.5 6.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Attachment_P66 PF11263.8 EEQ34658.1 - 0.25 10.6 0.1 0.34 10.2 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 ESSS PF10183.9 EEQ34658.1 - 0.26 11.5 0.3 0.26 11.5 0.3 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3546 PF12066.8 EEQ34660.1 - 4.2e-29 101.0 0.9 4.2e-29 101.0 0.9 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EEQ34660.1 - 4.9e-12 45.4 0.2 1.1e-11 44.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 EEQ34660.1 - 2.2e-11 44.5 0.2 6.9e-11 42.9 0.2 1.9 1 0 0 1 1 1 1 Arsenite-resistance protein 2 CBFB_NFYA PF02045.15 EEQ34661.1 - 1.2e-28 99.4 4.6 2.5e-28 98.4 4.6 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 EEQ34661.1 - 0.052 12.7 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein Kinesin PF00225.23 EEQ34662.1 - 2.6e-111 371.8 0.0 3.8e-111 371.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 EEQ34662.1 - 1.9e-44 152.0 0.0 5e-44 150.7 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 EEQ34662.1 - 1.1e-40 139.8 0.4 1.6e-31 109.9 0.2 3.0 2 0 0 2 2 2 2 Kinesin-associated Microtub_bd PF16796.5 EEQ34662.1 - 1.2e-24 86.9 0.0 2.9e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 EEQ34662.1 - 1.1e-07 32.1 0.2 4.4e-07 30.2 0.2 2.1 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 EEQ34662.1 - 5.5e-06 26.6 0.2 3.6e-05 24.0 0.1 2.5 2 0 0 2 2 2 1 FHA domain PH PF00169.29 EEQ34662.1 - 6.5e-05 23.4 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Yop-YscD_cpl PF16697.5 EEQ34662.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain 3-dmu-9_3-mt PF06983.13 EEQ34663.1 - 3.8e-39 133.8 0.1 5.8e-39 133.2 0.1 1.3 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DSX_dimer PF08828.10 EEQ34663.1 - 0.038 13.7 0.4 0.08 12.6 0.2 1.7 2 0 0 2 2 2 0 Doublesex dimerisation domain Phosphodiest PF01663.22 EEQ34664.1 - 4.8e-89 299.4 0.1 6e-89 299.1 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EEQ34664.1 - 0.00016 21.2 0.0 0.2 11.0 0.0 2.2 1 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 EEQ34664.1 - 0.0043 16.4 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 EEQ34664.1 - 0.038 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 PglZ domain DUF1043 PF06295.12 EEQ34665.1 - 0.3 11.1 2.1 2.8 7.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF3760 PF12586.8 EEQ34666.1 - 0.08 13.1 0.2 0.28 11.4 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Helicase_IV_N PF12462.8 EEQ34666.1 - 0.17 11.8 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal Zn_clus PF00172.18 EEQ34667.1 - 0.0056 16.8 2.0 0.016 15.3 2.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 EEQ34668.1 - 7.6e-65 219.0 0.1 1.3e-64 218.2 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EEQ34668.1 - 2.3e-57 194.5 0.0 4.7e-57 193.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EEQ34668.1 - 3.4e-56 190.0 0.1 1.1e-55 188.4 0.0 2.0 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.21 EEQ34668.1 - 8.5e-43 147.1 0.0 1.5e-42 146.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ34668.1 - 6.9e-37 126.1 0.3 2.1e-36 124.5 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EEQ34668.1 - 2.6e-21 76.2 0.0 7e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EEQ34668.1 - 1.1e-18 67.8 0.0 4.4e-18 65.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EEQ34668.1 - 3.8e-16 60.3 0.0 5.9e-14 53.3 0.0 4.3 4 1 1 5 5 4 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EEQ34668.1 - 6.4e-12 45.6 0.0 1.7e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ34668.1 - 7.2e-12 45.9 0.0 3.1e-11 43.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EEQ34668.1 - 6.6e-11 42.0 0.0 1.9e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EEQ34668.1 - 1.6e-10 41.1 0.0 1e-09 38.5 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 EEQ34668.1 - 3.9e-09 37.1 0.0 1.7e-08 35.0 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ34668.1 - 2.2e-07 30.5 0.0 5.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 EEQ34668.1 - 2.3e-07 31.1 0.0 7.7e-07 29.4 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EEQ34668.1 - 7.5e-07 29.1 0.0 2.2e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EEQ34668.1 - 6.1e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EEQ34668.1 - 0.00019 20.9 0.1 0.00048 19.6 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_24 PF13578.6 EEQ34668.1 - 0.0033 18.4 0.0 0.022 15.8 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.22 EEQ34669.1 - 6.1e-44 150.5 0.0 3e-25 88.9 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 HlyD PF00529.20 EEQ34669.1 - 0.12 12.2 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS FAD_binding_3 PF01494.19 EEQ34670.1 - 5.5e-21 75.2 0.1 7.9e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EEQ34670.1 - 1.4e-07 31.2 0.5 0.00099 18.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EEQ34670.1 - 4.1e-06 26.2 0.6 0.001 18.4 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ34670.1 - 5.1e-06 26.6 0.3 1.5e-05 25.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ34670.1 - 9.7e-05 22.9 1.0 0.0032 18.0 0.2 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ34670.1 - 0.00038 20.2 0.7 0.0092 15.6 0.4 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EEQ34670.1 - 0.00045 19.6 0.0 0.058 12.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEQ34670.1 - 0.00083 18.5 1.3 0.0013 17.9 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EEQ34670.1 - 0.0012 18.0 1.0 0.02 14.0 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EEQ34670.1 - 0.0034 16.3 0.9 0.017 14.0 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 EEQ34670.1 - 0.058 12.1 0.3 0.29 9.8 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 EEQ34670.1 - 0.082 12.0 0.5 0.17 11.0 0.5 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 EEQ34670.1 - 0.14 11.4 0.2 0.24 10.6 0.2 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EEQ34670.1 - 0.53 9.5 2.1 16 4.7 0.3 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_membrane PF00664.23 EEQ34671.1 - 6.9e-104 347.3 39.7 2e-55 188.4 12.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ34671.1 - 1.8e-67 226.0 0.0 1.5e-32 112.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ34671.1 - 2.8e-14 53.1 0.0 7.8e-05 22.2 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ34671.1 - 6.5e-07 29.0 0.4 0.0039 16.9 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ34671.1 - 2.6e-06 27.4 0.0 0.16 11.9 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 EEQ34671.1 - 7.8e-06 25.8 0.4 0.44 10.2 0.0 3.5 3 1 1 4 4 4 2 AAA ATPase domain AAA_21 PF13304.6 EEQ34671.1 - 1.1e-05 25.4 3.1 0.11 12.3 0.2 4.1 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 EEQ34671.1 - 2.7e-05 23.2 3.4 0.046 12.5 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EEQ34671.1 - 3.2e-05 24.4 5.5 0.046 14.1 0.1 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EEQ34671.1 - 0.00023 21.4 1.4 1.2 9.4 0.0 3.7 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EEQ34671.1 - 0.00024 20.5 0.3 0.15 11.3 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_25 PF13481.6 EEQ34671.1 - 0.00094 18.8 0.0 0.43 10.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EEQ34671.1 - 0.0016 18.2 3.3 1.8 8.2 0.5 4.0 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EEQ34671.1 - 0.0034 17.9 0.0 0.75 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 EEQ34671.1 - 0.007 15.6 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit SbcCD_C PF13558.6 EEQ34671.1 - 0.0076 16.5 3.4 4.2 7.7 0.5 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EEQ34671.1 - 0.0083 15.7 0.0 5.2 6.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EEQ34671.1 - 0.0093 16.2 0.4 1 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EEQ34671.1 - 0.018 15.2 0.2 6.7 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EEQ34671.1 - 0.054 14.1 0.0 17 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EEQ34671.1 - 0.093 12.7 0.4 22 5.0 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EEQ34671.1 - 0.12 12.5 0.1 24 5.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EEQ34671.1 - 0.14 12.6 0.1 10 6.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 EEQ34671.1 - 0.15 11.8 0.1 5.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EEQ34671.1 - 0.18 11.5 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EEQ34671.1 - 0.25 11.4 0.8 5.4 7.0 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Transferase PF02458.15 EEQ34672.1 - 1.1e-10 40.8 0.0 2e-08 33.3 0.0 2.7 3 0 0 3 3 3 2 Transferase family FSH1 PF03959.13 EEQ34673.1 - 2.3e-28 99.3 0.0 1.1e-26 93.8 0.0 2.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EEQ34673.1 - 8.8e-06 26.5 0.0 1.1e-05 26.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EEQ34673.1 - 0.0095 15.8 0.2 0.67 9.7 0.1 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EEQ34673.1 - 0.041 13.1 0.0 0.13 11.5 0.0 1.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 p450 PF00067.22 EEQ34674.1 - 5.8e-34 117.6 0.0 7.2e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Herpes_US9 PF06072.11 EEQ34676.1 - 0.14 12.0 1.1 0.31 11.0 1.1 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Prominin PF05478.11 EEQ34676.1 - 1.3 6.8 9.0 2 6.3 9.0 1.1 1 0 0 1 1 1 0 Prominin SNARE PF05739.19 EEQ34676.1 - 2 8.5 6.3 4.2 7.4 6.3 1.4 1 0 0 1 1 1 0 SNARE domain HLH PF00010.26 EEQ34677.1 - 1.2e-15 57.2 1.1 3.1e-15 55.9 0.6 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4776 PF16003.5 EEQ34677.1 - 1.1 8.2 8.9 0.051 12.6 2.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) YabA PF06156.13 EEQ34677.1 - 1.6 9.4 6.3 0.43 11.2 1.2 2.3 2 0 0 2 2 2 0 Initiation control protein YabA IFT20 PF14931.6 EEQ34677.1 - 3.8 7.7 11.3 0.17 12.1 4.6 2.0 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 APG6_N PF17675.1 EEQ34677.1 - 5.9 7.4 14.3 1 9.9 7.5 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 EEQ34677.1 - 7.9 6.8 20.7 8 6.8 11.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ferlin_C PF16165.5 EEQ34678.1 - 0.59 10.1 2.9 0.89 9.5 2.9 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Ofd1_CTDD PF10637.9 EEQ34680.1 - 4.1e-94 314.7 0.1 3.3e-92 308.5 0.2 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EEQ34680.1 - 6e-25 87.7 0.0 2.3e-24 85.8 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EEQ34680.1 - 9.1e-14 52.1 0.0 2.8e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily APH PF01636.23 EEQ34681.1 - 2.6e-09 37.4 0.0 9.4e-09 35.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Nup88 PF10168.9 EEQ34682.1 - 0.12 10.2 0.1 0.16 9.8 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore component COesterase PF00135.28 EEQ34683.1 - 5e-79 266.5 0.0 6.8e-79 266.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EEQ34683.1 - 5.8e-06 26.3 0.3 0.081 12.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ34683.1 - 0.024 14.1 0.2 0.041 13.4 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Endopep_inhib PF16800.5 EEQ34683.1 - 0.04 13.9 0.3 0.079 12.9 0.2 1.5 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor Fungal_lectin_2 PF18647.1 EEQ34684.1 - 2.8e-05 24.5 2.7 9e-05 22.9 2.7 1.9 1 1 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin DUF4397 PF14344.6 EEQ34687.1 - 0.00037 21.3 0.1 0.0049 17.6 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4397) p450 PF00067.22 EEQ34689.1 - 2.9e-70 237.3 0.0 4e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.22 EEQ34689.1 - 0.0068 16.4 0.4 0.013 15.5 0.4 1.4 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit HNH_2 PF13391.6 EEQ34691.1 - 5.4e-19 68.1 0.0 4e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease HNH_2 PF13391.6 EEQ34692.1 - 1.8e-14 53.6 1.0 2.9e-14 53.0 0.2 1.8 2 0 0 2 2 2 1 HNH endonuclease RhoGAP PF00620.27 EEQ34695.1 - 2e-33 115.4 0.1 3.9e-33 114.4 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EEQ34695.1 - 1.1e-28 99.2 33.8 1.1e-11 44.7 6.1 4.9 5 0 0 5 5 5 4 LIM domain Nudc_N PF14050.6 EEQ34695.1 - 0.18 11.8 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. SPX PF03105.19 EEQ34695.1 - 1.9 8.4 5.9 5.8 6.7 0.1 2.2 2 0 0 2 2 2 0 SPX domain AMP-binding PF00501.28 EEQ34696.1 - 7.4e-70 235.7 0.0 1.4e-69 234.8 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ34696.1 - 7.8e-06 26.8 0.0 1.6e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNA_pol_Rpb4 PF03874.16 EEQ34697.1 - 1.3e-22 80.4 2.9 1.8e-22 80.0 2.9 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 EEQ34697.1 - 0.0036 16.9 0.4 0.0041 16.8 0.4 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Met_10 PF02475.16 EEQ34698.1 - 5.6e-67 225.4 0.0 7.4e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 EEQ34698.1 - 0.037 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Opi1 PF08618.10 EEQ34700.1 - 0.0028 17.0 3.5 0.0048 16.2 3.5 1.6 1 0 0 1 1 1 1 Transcription factor Opi1 zf-GRF PF06839.12 EEQ34701.1 - 4.4e-12 45.9 4.9 8.3e-12 45.0 4.9 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF1192 PF06698.11 EEQ34701.1 - 0.95 9.6 5.5 4.2 7.5 5.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3818 PF12825.7 EEQ34702.1 - 3.6e-122 407.6 10.6 3.2e-80 269.7 2.1 2.6 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EEQ34702.1 - 1.4e-39 135.1 0.2 2.6e-39 134.2 0.2 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EEQ34702.1 - 1.6e-11 44.2 0.1 5e-10 39.4 0.0 3.2 3 1 0 3 3 3 1 PX domain GFD1 PF17331.2 EEQ34702.1 - 0.14 12.3 2.7 0.58 10.4 2.7 2.0 1 0 0 1 1 1 0 GFD1 mRNA transport factor Aldo_ket_red PF00248.21 EEQ34703.1 - 1e-51 175.9 0.0 3.5e-51 174.1 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family TnpV PF14198.6 EEQ34703.1 - 0.039 14.0 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Hydrolase_6 PF13344.6 EEQ34704.1 - 2e-20 72.8 0.0 4.9e-20 71.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ34704.1 - 5.2e-17 61.7 0.0 1.1e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EEQ34704.1 - 0.0069 16.7 0.0 2 8.7 0.0 3.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEQ34704.1 - 0.0071 16.8 0.0 0.22 11.9 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ34704.1 - 0.018 15.1 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Apt1 PF10351.9 EEQ34704.1 - 0.13 11.1 1.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Crystall PF00030.19 EEQ34705.1 - 0.0053 16.9 0.0 0.0062 16.7 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 EEQ34705.1 - 0.029 14.3 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor family I36 MFS_5 PF05631.14 EEQ34706.1 - 2.6e-61 207.5 3.6 3.6e-61 207.0 3.6 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EEQ34706.1 - 5.2e-22 78.2 21.7 1.2e-21 77.0 21.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ34706.1 - 5.6e-07 28.8 8.5 5.6e-07 28.8 8.5 3.4 3 1 1 4 4 4 2 Sugar (and other) transporter UAA PF08449.11 EEQ34707.1 - 7.3e-75 252.0 11.1 1.7e-74 250.7 11.1 1.6 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 EEQ34707.1 - 0.64 9.3 15.8 2.2 7.5 3.3 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.20 EEQ34707.1 - 4.9 7.3 31.6 0.27 11.4 6.1 3.4 3 1 0 3 3 3 0 EamA-like transporter family Rad17 PF03215.15 EEQ34708.1 - 2.9e-27 95.8 0.0 5.4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EEQ34708.1 - 0.00032 21.1 0.0 0.00074 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EEQ34708.1 - 0.003 16.7 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 EEQ34708.1 - 0.011 16.3 1.5 0.19 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EEQ34708.1 - 0.012 15.4 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EEQ34708.1 - 0.018 15.1 0.0 0.053 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ34708.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EEQ34708.1 - 0.073 13.5 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EEQ34708.1 - 0.079 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 EEQ34708.1 - 0.082 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_11 PF13086.6 EEQ34708.1 - 0.17 11.7 2.9 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EEQ34708.1 - 0.17 12.1 0.4 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EEQ34708.1 - 0.25 10.3 0.0 0.42 9.5 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region ELMO_CED12 PF04727.13 EEQ34709.1 - 1.6e-51 174.9 0.1 2.9e-51 174.1 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 EEQ34709.1 - 1.8e-26 93.3 0.2 3.9e-26 92.2 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 EEQ34709.1 - 1.2e-16 61.0 0.0 3.2e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) DUF1752 PF08550.10 EEQ34710.1 - 7.1e-10 38.5 3.9 1.7e-09 37.3 3.9 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUI1 PF01253.22 EEQ34712.1 - 7.3e-24 84.1 0.1 1.6e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 R3H-assoc PF13902.6 EEQ34712.1 - 0.011 16.1 0.8 0.02 15.3 0.8 1.3 1 0 0 1 1 1 0 R3H-associated N-terminal domain Img2 PF05046.14 EEQ34712.1 - 0.027 14.7 0.2 0.067 13.5 0.2 1.7 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) SRP14 PF02290.15 EEQ34712.1 - 0.048 14.0 0.3 0.081 13.3 0.3 1.4 1 0 0 1 1 1 0 Signal recognition particle 14kD protein TnpV PF14198.6 EEQ34712.1 - 0.056 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV BLOC1_2 PF10046.9 EEQ34713.1 - 0.047 14.0 0.2 0.12 12.6 0.2 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cgr1 PF03879.14 EEQ34714.1 - 5.8e-34 116.7 30.9 6.6e-34 116.5 30.9 1.0 1 0 0 1 1 1 1 Cgr1 family Vfa1 PF08432.10 EEQ34714.1 - 0.15 12.4 11.8 0.17 12.2 11.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_11 PF13086.6 EEQ34714.1 - 1.9 8.2 9.2 2 8.1 9.2 1.0 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 EEQ34715.1 - 3.8e-66 219.1 0.5 2.5e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.23 EEQ34717.1 - 4.7e-14 52.1 0.7 5.4e-14 51.9 0.7 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EEQ34717.1 - 1.4e-07 31.8 0.1 1.9e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EEQ34717.1 - 0.00011 21.9 2.3 0.00047 19.8 0.2 2.0 1 1 1 2 2 2 1 A distinct subfamily of CDD/CDA-like deaminases Transp_cyt_pur PF02133.15 EEQ34718.1 - 2.3e-95 319.9 33.7 3.3e-95 319.5 33.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin LapA_dom PF06305.11 EEQ34718.1 - 0.15 11.9 1.2 12 5.8 0.0 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Polysacc_deac_1 PF01522.21 EEQ34719.1 - 8.2e-15 54.8 0.0 1.3e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase SOG2 PF10428.9 EEQ34719.1 - 0.039 13.2 13.8 0.048 12.9 13.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 EEQ34719.1 - 0.15 10.9 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PRCC PF10253.9 EEQ34719.1 - 2.4 8.9 10.0 3.9 8.2 10.0 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Tim54 PF11711.8 EEQ34719.1 - 9.1 4.9 6.4 12 4.5 6.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sortilin-Vps10 PF15902.5 EEQ34720.1 - 3.3e-280 929.2 6.9 1.2e-151 505.6 2.3 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EEQ34720.1 - 3.9e-87 290.9 18.3 2.7e-44 151.5 6.8 2.9 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EEQ34720.1 - 5.8e-11 40.7 24.2 0.22 11.6 0.1 9.9 9 0 0 9 9 9 4 BNR/Asp-box repeat BNR_2 PF13088.6 EEQ34720.1 - 2.7e-06 26.9 0.1 0.45 9.8 0.0 5.0 4 2 1 5 5 5 2 BNR repeat-like domain BNR_6 PF15899.5 EEQ34720.1 - 0.076 13.1 14.0 1.2 9.4 0.3 6.1 7 0 0 7 7 7 0 BNR-Asp box repeat CHB_HEX_C PF03174.13 EEQ34720.1 - 0.13 12.3 0.1 8.5 6.4 0.1 3.0 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain UBM PF14377.6 EEQ34721.1 - 0.11 12.0 0.1 4.2 7.0 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin binding region MREG PF15812.5 EEQ34722.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Melanoregulin TFIIS_M PF07500.14 EEQ34723.1 - 1.4e-30 106.1 1.3 2.2e-30 105.4 0.4 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EEQ34723.1 - 1.9e-18 66.0 4.7 3e-18 65.4 4.7 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EEQ34723.1 - 2.9e-13 49.6 0.5 6.2e-13 48.5 0.5 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 EEQ34723.1 - 0.092 12.4 0.1 0.092 12.4 0.1 2.0 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Flavodoxin_3 PF12641.7 EEQ34723.1 - 0.099 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain zf-LITAF-like PF10601.9 EEQ34723.1 - 0.2 11.9 1.9 0.39 11.0 1.9 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Sec10 PF07393.11 EEQ34726.1 - 7.2e-237 788.3 0.0 8.4e-237 788.1 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MarR_2 PF12802.7 EEQ34726.1 - 0.056 13.3 0.1 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 MarR family MBOAT_2 PF13813.6 EEQ34727.1 - 9.9e-17 61.0 0.3 2.6e-16 59.7 0.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF2585 PF10755.9 EEQ34727.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) LRR_6 PF13516.6 EEQ34728.1 - 1.4e-11 43.4 2.5 0.011 15.7 0.0 7.3 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.7 EEQ34728.1 - 6.1e-09 36.0 3.1 0.026 14.9 0.3 5.6 5 2 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EEQ34728.1 - 0.00027 21.0 2.9 32 5.6 0.1 6.7 7 0 0 7 7 7 1 Leucine Rich Repeat DARPP-32 PF05395.12 EEQ34728.1 - 0.34 11.1 9.4 0.57 10.4 9.4 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 NOA36 PF06524.12 EEQ34728.1 - 5.3 6.3 8.5 7.4 5.8 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein COX17 PF05051.13 EEQ34729.1 - 4.6e-21 74.9 5.9 5.6e-21 74.6 5.9 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EEQ34729.1 - 0.042 13.9 4.9 0.054 13.5 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Alg6_Alg8 PF03155.15 EEQ34730.1 - 5.6e-126 421.3 23.7 3.6e-79 267.0 7.0 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.22 EEQ34731.1 - 2.1e-39 133.2 0.1 6.3e-19 67.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ34731.1 - 0.00013 22.1 0.0 0.71 10.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif ABC2_membrane_5 PF13346.6 EEQ34732.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein NMT1 PF09084.11 EEQ34733.1 - 1.9e-79 266.6 0.0 2.4e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EEQ34733.1 - 9.3e-06 25.5 0.1 0.42 10.2 0.0 3.4 3 1 1 4 4 4 2 NMT1-like family Ribosomal_L37 PF08561.10 EEQ34734.1 - 3.3e-44 150.3 0.9 4.3e-44 149.9 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Stevor PF17410.2 EEQ34735.1 - 0.061 12.9 0.2 0.086 12.4 0.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Gly-zipper_Omp PF13488.6 EEQ34735.1 - 0.13 12.3 1.8 0.21 11.6 1.8 1.3 1 0 0 1 1 1 0 Glycine zipper HGTP_anticodon PF03129.20 EEQ34736.1 - 5.4e-22 77.8 0.0 3.6e-21 75.1 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EEQ34736.1 - 9e-09 35.5 0.0 2.8e-07 30.7 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) MFS_1 PF07690.16 EEQ34737.1 - 1.4e-27 96.6 31.2 1.4e-26 93.2 16.4 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily FPN1 PF06963.12 EEQ34737.1 - 0.0019 16.9 0.2 0.0049 15.5 0.2 1.7 1 0 0 1 1 1 1 Ferroportin1 (FPN1) OATP PF03137.20 EEQ34737.1 - 0.033 12.5 9.2 0.041 12.2 7.1 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EEQ34737.1 - 0.31 9.9 12.0 0.028 13.3 0.9 2.8 2 1 1 3 3 3 0 MFS_1 like family Cpn60_TCP1 PF00118.24 EEQ34738.1 - 7.6e-134 447.0 14.8 9.3e-134 446.7 14.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.6 EEQ34738.1 - 0.066 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) AAA PF00004.29 EEQ34739.1 - 6.1e-41 139.9 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ34739.1 - 3.3e-05 23.6 0.0 7.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EEQ34739.1 - 7.3e-05 23.1 0.0 0.0073 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EEQ34739.1 - 0.00012 22.1 0.0 0.00043 20.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ34739.1 - 0.00029 21.0 0.0 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EEQ34739.1 - 0.00035 21.0 0.3 0.0076 16.7 0.1 2.4 2 1 1 3 3 2 1 AAA ATPase domain DUF815 PF05673.13 EEQ34739.1 - 0.0022 17.2 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EEQ34739.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EEQ34739.1 - 0.019 15.2 0.1 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EEQ34739.1 - 0.039 14.3 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 EEQ34739.1 - 0.049 13.1 0.0 0.16 11.4 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EEQ34739.1 - 0.051 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EEQ34739.1 - 0.069 12.9 0.1 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EEQ34739.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EEQ34739.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ34739.1 - 0.1 13.2 0.0 0.49 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EEQ34739.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EEQ34739.1 - 0.17 11.2 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FAD_binding_2 PF00890.24 EEQ34740.1 - 2.7e-125 418.8 3.7 3.4e-125 418.4 3.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EEQ34740.1 - 3.3e-44 149.9 0.9 5e-44 149.4 0.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EEQ34740.1 - 6.3e-06 25.6 0.2 0.00099 18.4 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EEQ34740.1 - 7.5e-06 25.3 1.1 0.014 14.5 2.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EEQ34740.1 - 7.5e-05 22.1 0.2 0.055 12.7 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EEQ34740.1 - 0.0043 16.4 0.6 0.0085 15.4 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EEQ34740.1 - 0.051 13.2 1.9 0.19 11.3 1.9 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EEQ34740.1 - 0.19 10.4 1.1 0.94 8.1 0.7 2.3 3 0 0 3 3 3 0 HI0933-like protein DPPIV_N PF00930.21 EEQ34741.1 - 1.3e-111 372.8 0.6 1.7e-111 372.4 0.6 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EEQ34741.1 - 3.1e-56 190.2 6.3 4.1e-56 189.8 4.8 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EEQ34741.1 - 5.5e-07 29.4 0.4 2.4e-06 27.3 0.2 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EEQ34741.1 - 0.0052 17.4 0.1 0.19 12.3 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EEQ34741.1 - 0.048 13.5 0.4 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EEQ34741.1 - 0.048 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 EEQ34741.1 - 0.07 11.8 0.0 0.25 10.0 0.0 1.8 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) PI-PLC-X PF00388.19 EEQ34742.1 - 7.8e-51 171.5 3.6 4.3e-37 126.9 0.0 2.7 3 0 0 3 3 3 2 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EEQ34742.1 - 1.7e-41 141.2 0.0 3.3e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain HECT_2 PF09814.9 EEQ34743.1 - 6.3e-43 147.1 0.1 7.7e-43 146.8 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding HECT_2 PF09814.9 EEQ34744.1 - 1.3e-46 159.2 0.0 1.6e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Questin_oxidase PF14027.6 EEQ34746.1 - 7.5e-81 272.3 0.0 8.8e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like TPR_12 PF13424.6 EEQ34747.1 - 3.8e-47 158.5 10.2 1.6e-16 60.4 0.7 5.7 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ34747.1 - 3.8e-46 153.8 14.1 9.9e-10 38.0 0.1 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ34747.1 - 2.7e-12 45.8 15.0 0.025 14.7 0.0 6.5 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ34747.1 - 2.8e-11 42.6 11.6 0.03 14.3 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ34747.1 - 4.6e-09 35.7 13.6 0.0013 18.4 0.2 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ34747.1 - 1.5e-08 35.2 13.4 0.22 12.2 0.0 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ34747.1 - 3.7e-06 26.7 17.5 0.16 12.3 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ34747.1 - 0.00068 19.1 4.9 0.13 11.6 0.8 3.1 2 1 1 3 3 3 2 MalT-like TPR region TPR_14 PF13428.6 EEQ34747.1 - 0.0015 19.1 6.5 26 6.0 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EEQ34747.1 - 0.0099 16.4 4.1 8.5 7.3 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ34747.1 - 0.015 15.8 11.6 3.1 8.4 0.0 4.6 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ34747.1 - 0.03 14.7 10.3 2.1 8.9 0.5 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ34747.1 - 0.032 14.5 5.2 0.15 12.3 0.6 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2989 PF11207.8 EEQ34747.1 - 0.22 11.3 2.3 0.4 10.4 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) TPR_6 PF13174.6 EEQ34747.1 - 0.31 11.8 6.8 15 6.5 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 EEQ34747.1 - 1.9 8.6 12.1 0.45 10.6 0.2 3.6 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain AAA PF00004.29 EEQ34748.1 - 1.6e-48 164.4 0.0 6.1e-43 146.4 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ34748.1 - 5.2e-05 23.7 0.0 0.023 15.1 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 EEQ34748.1 - 6.8e-05 22.6 4.1 0.014 15.2 0.0 3.2 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 EEQ34748.1 - 0.00013 21.7 0.0 0.00042 20.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EEQ34748.1 - 0.00052 19.2 0.0 0.00094 18.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 EEQ34748.1 - 0.00068 20.0 0.1 0.016 15.6 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_2 PF07724.14 EEQ34748.1 - 0.0033 17.6 0.0 0.0082 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EEQ34748.1 - 0.0033 17.7 0.0 0.045 14.0 0.0 3.0 3 1 1 4 4 2 1 AAA domain PhoH PF02562.16 EEQ34748.1 - 0.0042 16.6 0.0 0.2 11.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 EEQ34748.1 - 0.0061 16.2 0.0 0.064 12.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EEQ34748.1 - 0.0065 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EEQ34748.1 - 0.0079 16.4 0.0 0.44 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EEQ34748.1 - 0.0083 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EEQ34748.1 - 0.02 15.5 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EEQ34748.1 - 0.021 14.2 0.1 0.05 13.0 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EEQ34748.1 - 0.022 14.1 0.2 0.08 12.3 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 EEQ34748.1 - 0.033 13.7 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EEQ34748.1 - 0.033 14.2 0.0 0.13 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EEQ34748.1 - 0.034 14.2 0.2 0.16 12.0 0.0 2.1 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vps4_C PF09336.10 EEQ34748.1 - 0.047 13.7 0.4 0.69 10.0 0.1 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 EEQ34748.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EEQ34748.1 - 0.15 11.8 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-C2H2 PF00096.26 EEQ34749.1 - 0.00032 21.0 16.9 0.0029 18.0 5.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type C1_4 PF07975.12 EEQ34749.1 - 0.055 13.7 0.4 0.17 12.2 0.4 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain zf-H2C2_2 PF13465.6 EEQ34749.1 - 2.9 8.5 16.5 15 6.2 2.3 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ34749.1 - 3.5 8.7 19.2 0.081 13.8 4.9 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Dynamin_M PF01031.20 EEQ34750.1 - 1e-110 369.4 0.0 1.8e-110 368.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EEQ34750.1 - 7e-57 192.1 0.7 2.1e-56 190.6 0.0 2.2 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 EEQ34750.1 - 7.3e-32 109.4 0.8 1.9e-31 108.1 0.8 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EEQ34750.1 - 0.00012 22.1 0.5 0.0016 18.5 0.5 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SH3_9 PF14604.6 EEQ34751.1 - 6.1e-30 102.8 3.6 3.8e-14 52.3 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EEQ34751.1 - 1.9e-29 101.0 4.2 1.9e-14 53.0 0.4 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EEQ34751.1 - 6.4e-16 57.8 0.0 2.6e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 EEQ34751.1 - 8e-16 57.9 0.0 1.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein APH PF01636.23 EEQ34752.1 - 3.8e-12 46.6 0.0 1e-11 45.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ34752.1 - 0.0026 17.4 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Brix PF04427.18 EEQ34753.1 - 2e-35 122.7 0.0 2.6e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain PX PF00787.24 EEQ34755.1 - 1e-12 48.1 0.5 3.2e-12 46.4 0.2 1.9 2 1 0 2 2 2 1 PX domain SAS4 PF15460.6 EEQ34756.1 - 4.4e-32 110.1 4.6 1.3e-31 108.6 4.6 1.8 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Pes-10 PF07149.11 EEQ34756.1 - 0.054 12.6 8.8 0.079 12.0 8.8 1.2 1 0 0 1 1 1 0 Pes-10 DUF3090 PF11290.8 EEQ34756.1 - 0.6 9.9 3.4 1.2 8.9 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) TUSC2 PF15000.6 EEQ34756.1 - 3.6 7.9 8.0 0.92 9.8 3.7 2.3 2 0 0 2 2 2 0 Tumour suppressor candidate 2 NOA36 PF06524.12 EEQ34756.1 - 3.8 6.7 8.3 1.9 7.7 6.1 1.6 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 EEQ34756.1 - 6.1 7.3 14.6 14 6.1 14.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EEQ34756.1 - 8 4.4 16.2 13 3.8 16.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EEQ34756.1 - 8.1 4.6 14.9 17 3.5 14.9 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF3807 PF12720.7 EEQ34759.1 - 4.3e-41 141.2 4.6 6.1e-41 140.7 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) HVSL PF09749.9 EEQ34761.1 - 6.7e-80 268.0 0.6 8.4e-80 267.7 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.11 EEQ34763.1 - 1.7e-07 32.1 0.0 3.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein Methyltransf_28 PF02636.17 EEQ34764.1 - 3.9e-40 138.1 0.0 5.2e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pathogen_betaC1 PF09593.10 EEQ34764.1 - 0.092 12.7 0.4 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein PALP PF00291.25 EEQ34765.1 - 1.1e-61 208.9 1.3 2.3e-61 207.8 1.3 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scm3 PF10384.9 EEQ34766.1 - 1.8e-22 78.8 0.1 3.8e-22 77.8 0.1 1.6 1 0 0 1 1 1 1 Centromere protein Scm3 BTB PF00651.31 EEQ34767.1 - 0.024 14.8 0.3 0.08 13.2 0.1 1.8 2 0 0 2 2 2 0 BTB/POZ domain APH PF01636.23 EEQ34768.1 - 1.2e-09 38.5 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ34768.1 - 0.034 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EEQ34768.1 - 0.095 11.5 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.22 EEQ34768.1 - 0.25 10.9 0.0 0.39 10.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APG6 PF04111.12 EEQ34769.1 - 2.8e-72 242.4 0.0 5e-72 241.6 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EEQ34769.1 - 6.9e-40 136.7 7.4 1.4e-39 135.7 7.4 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region YabA PF06156.13 EEQ34769.1 - 0.09 13.4 1.1 0.23 12.1 1.1 1.6 1 0 0 1 1 1 0 Initiation control protein YabA UPF0242 PF06785.11 EEQ34769.1 - 0.1 12.7 3.7 0.26 11.4 3.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Aminotran_5 PF00266.19 EEQ34770.1 - 1.5e-26 93.2 0.0 2.4e-26 92.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Peroxin-13_N PF04088.13 EEQ34771.1 - 9.2e-54 181.7 0.1 1.7e-53 180.8 0.1 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EEQ34771.1 - 2.6e-09 36.6 0.0 4.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEQ34771.1 - 5e-08 32.4 0.0 8.9e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ34771.1 - 1.9e-06 27.6 0.1 3.1e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 EEQ34771.1 - 0.24 11.9 0.0 0.43 11.0 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain GST_C PF00043.25 EEQ34772.1 - 2.3e-09 37.4 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ34772.1 - 1.1e-07 32.0 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EEQ34772.1 - 0.0032 17.8 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ34772.1 - 0.0054 16.7 0.0 0.014 15.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EEQ34772.1 - 0.019 15.3 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1894 PF08979.11 EEQ34772.1 - 0.079 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1894) GST_N_2 PF13409.6 EEQ34772.1 - 0.11 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ERO1 PF04137.15 EEQ34773.1 - 2.1e-134 448.2 0.0 2.6e-134 447.9 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TPP_enzyme_N PF02776.18 EEQ34774.1 - 1.8e-45 154.6 0.1 3.7e-45 153.6 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEQ34774.1 - 7.1e-35 119.7 0.0 1.3e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EEQ34774.1 - 3.2e-18 66.0 0.0 9e-18 64.5 0.0 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 EEQ34774.1 - 0.00053 20.0 0.2 0.0032 17.5 0.3 2.3 2 0 0 2 2 2 1 B12 binding domain CO_dh PF02552.16 EEQ34774.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TPR_1 PF00515.28 EEQ34775.1 - 9.4e-26 88.5 1.8 2.8e-09 36.4 0.0 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ34775.1 - 2.8e-23 80.1 2.9 1.4e-07 31.0 0.0 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ34775.1 - 1.7e-18 66.0 4.1 1.8e-08 33.9 0.0 4.8 4 1 0 4 4 4 3 TPR repeat TPR_16 PF13432.6 EEQ34775.1 - 2e-18 66.8 1.0 1.7e-05 25.3 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ34775.1 - 2.6e-16 58.9 2.9 3.6e-05 24.2 0.0 5.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ34775.1 - 1.4e-15 56.1 2.1 7.3e-07 28.9 0.0 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ34775.1 - 3.6e-14 52.0 1.7 0.0028 17.9 0.1 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ34775.1 - 7.1e-13 48.9 8.8 0.00029 21.3 0.0 4.7 4 1 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ34775.1 - 1.8e-10 40.1 1.1 0.0071 16.3 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ34775.1 - 9.9e-10 38.6 5.2 8.1e-06 26.0 0.3 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 EEQ34775.1 - 1e-09 38.6 0.2 0.0051 17.1 0.0 4.1 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ34775.1 - 2.1e-09 37.4 0.6 0.0041 17.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ34775.1 - 2.8e-06 27.6 2.7 2.4 9.0 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ34775.1 - 6.2e-06 26.4 1.4 0.0025 18.0 0.1 2.7 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EEQ34775.1 - 0.00017 20.9 0.6 0.24 10.6 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 EEQ34775.1 - 0.0026 17.7 0.1 4.3 7.4 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat MIT PF04212.18 EEQ34775.1 - 0.0043 17.1 0.1 10 6.3 0.1 4.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EEQ34775.1 - 0.012 15.4 4.1 0.085 12.8 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1641 PF07849.11 EEQ34775.1 - 0.027 14.3 0.1 0.059 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) NatB_MDM20 PF09797.9 EEQ34775.1 - 0.08 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF4192 PF13830.6 EEQ34775.1 - 0.087 12.9 6.0 0.058 13.5 3.6 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4192) TOM20_plant PF06552.12 EEQ34775.1 - 0.1 12.3 0.1 4.3 7.1 0.0 2.6 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 RRM_1 PF00076.22 EEQ34776.1 - 7.7e-33 112.1 1.2 6.2e-18 64.4 0.1 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ34776.1 - 0.025 14.7 0.1 6.7 6.9 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif RRM_3 PF08777.11 EEQ34776.1 - 0.14 12.2 0.1 0.8 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Fungal_trans PF04082.18 EEQ34777.1 - 1.1e-15 57.5 0.1 2.3e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ34777.1 - 2.6e-06 27.4 12.0 6.1e-06 26.3 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 EEQ34777.1 - 0.018 14.9 0.3 0.039 13.8 0.3 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SnoaL PF07366.12 EEQ34779.1 - 0.032 14.0 0.0 0.25 11.2 0.0 2.4 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EEQ34779.1 - 0.057 14.1 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain APAF1_C PF17908.1 EEQ34779.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 APAF-1 helical domain SHS2_Rpb7-N PF03876.17 EEQ34780.1 - 1.4e-14 54.2 0.1 2.3e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EEQ34780.1 - 1.4e-11 44.6 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EEQ34780.1 - 0.023 14.9 0.0 0.044 14.0 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF962 PF06127.11 EEQ34781.1 - 2.2e-26 91.8 0.1 4e-26 90.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ATP-synt_ab PF00006.25 EEQ34782.1 - 1.5e-73 247.0 0.0 2.2e-73 246.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EEQ34782.1 - 1.2e-47 161.4 0.3 2e-47 160.6 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EEQ34782.1 - 6.3e-15 55.5 2.7 1.5e-14 54.3 2.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain THF_DHG_CYH PF00763.23 EEQ34783.1 - 1.7e-25 89.5 0.0 2.5e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EEQ34783.1 - 3.8e-12 45.8 0.1 6.2e-09 35.4 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fer2_BFD PF04324.15 EEQ34783.1 - 0.11 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain SPC25 PF06703.11 EEQ34784.1 - 3.1e-48 163.6 0.3 3.5e-48 163.5 0.3 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) EMC3_TMCO1 PF01956.16 EEQ34785.1 - 1.2e-53 181.3 0.5 1.5e-53 181.0 0.5 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Fasciclin PF02469.22 EEQ34786.1 - 0.04 14.2 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 Fasciclin domain MMS19_C PF12460.8 EEQ34787.1 - 1.3e-121 406.7 13.4 1.3e-121 406.7 13.4 3.9 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EEQ34787.1 - 7.2e-48 163.4 3.4 1.2e-38 133.2 0.0 5.3 4 2 2 6 6 6 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 EEQ34787.1 - 0.00015 21.7 2.4 26 5.4 0.1 6.5 6 0 0 6 6 6 0 HEAT repeat Cnd1 PF12717.7 EEQ34787.1 - 0.00026 21.1 2.8 0.11 12.6 0.0 4.2 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ34787.1 - 0.00034 20.9 3.1 4.2 7.8 0.2 4.9 4 0 0 4 4 4 2 HEAT repeats NUC173 PF08161.12 EEQ34787.1 - 0.13 11.9 1.6 2.4 7.8 0.1 3.5 4 0 0 4 4 4 0 NUC173 domain M11L PF11099.8 EEQ34787.1 - 0.35 11.1 2.4 18 5.6 0.1 3.0 3 0 0 3 3 3 0 Apoptosis regulator M11L like Ipi1_N PF12333.8 EEQ34787.1 - 0.52 10.9 2.6 20 5.8 0.0 4.3 5 1 1 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation SHE3 PF17078.5 EEQ34789.1 - 3.4e-08 33.5 28.7 2.6e-07 30.6 27.8 2.0 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 EEQ34789.1 - 0.011 15.9 38.6 1.1 9.4 21.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 EEQ34789.1 - 0.15 11.9 32.4 3.5 7.4 6.9 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH SecA_DEAD PF07517.14 EEQ34789.1 - 4.2 6.6 17.0 1.5 8.0 0.6 2.7 2 1 1 3 3 3 0 SecA DEAD-like domain DUF3632 PF12311.8 EEQ34790.1 - 2e-32 113.0 0.6 2e-32 113.0 0.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) FTA2 PF13095.6 EEQ34793.1 - 7.4e-05 22.5 0.8 0.0004 20.1 0.8 2.1 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EEQ34793.1 - 0.0003 20.2 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEQ34793.1 - 0.0006 19.3 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GPI-anchored PF10342.9 EEQ34794.1 - 9.1e-18 64.8 0.2 9.1e-18 64.8 0.2 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PRCC PF10253.9 EEQ34794.1 - 1.5 9.5 6.5 2.1 9.1 6.5 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 EEQ34794.1 - 4.2 6.5 14.9 4.3 6.4 14.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Methyltransf_31 PF13847.6 EEQ34796.1 - 4.1e-29 101.3 0.0 5.5e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ34796.1 - 4.5e-26 91.3 0.0 1.1e-25 90.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ34796.1 - 1.1e-24 86.9 0.0 2.2e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ34796.1 - 3e-17 62.7 0.0 4.2e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EEQ34796.1 - 4.2e-16 59.2 0.0 6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ34796.1 - 1.4e-15 57.9 0.0 3.1e-15 56.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.19 EEQ34796.1 - 1.8e-06 27.8 0.0 3.1e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EEQ34796.1 - 1.8e-06 27.6 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 EEQ34796.1 - 5.3e-06 26.2 0.0 1.1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 EEQ34796.1 - 4.7e-05 22.9 0.0 9.7e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.16 EEQ34796.1 - 0.00031 19.4 0.0 0.0004 19.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 EEQ34796.1 - 0.00051 19.4 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EEQ34796.1 - 0.00054 19.0 0.0 0.0008 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 EEQ34796.1 - 0.00062 19.4 0.0 0.00096 18.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 EEQ34796.1 - 0.0037 16.7 0.0 0.0049 16.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EEQ34796.1 - 0.0047 16.0 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 EEQ34796.1 - 0.024 14.0 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain DREV PF05219.12 EEQ34796.1 - 0.03 13.4 0.0 0.058 12.5 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.7 EEQ34796.1 - 0.032 14.2 0.0 0.11 12.4 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_8 PF05148.15 EEQ34796.1 - 0.032 14.1 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase GCD14 PF08704.10 EEQ34796.1 - 0.055 13.1 0.1 0.079 12.6 0.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PALP PF00291.25 EEQ34797.1 - 9e-35 120.5 0.0 1.1e-34 120.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_S9 PF00326.21 EEQ34798.1 - 8.3e-39 133.3 0.0 1.2e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EEQ34798.1 - 2e-10 40.6 0.0 6.7e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EEQ34798.1 - 1.1e-07 31.8 0.1 7.8e-05 22.4 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EEQ34798.1 - 2.8e-07 30.0 0.1 5.2e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 EEQ34798.1 - 1.7e-06 28.1 0.0 7e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EEQ34798.1 - 8e-06 25.9 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 EEQ34798.1 - 3.2e-05 22.8 0.0 0.00055 18.7 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EEQ34798.1 - 7.8e-05 22.4 0.5 0.019 14.6 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EEQ34798.1 - 0.00037 20.4 0.0 0.48 10.2 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.20 EEQ34798.1 - 0.003 17.2 0.0 0.0064 16.2 0.0 1.6 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 EEQ34798.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 EEQ34798.1 - 0.043 13.9 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein AMP-binding PF00501.28 EEQ34799.1 - 5.8e-148 493.0 0.0 1.6e-77 260.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EEQ34799.1 - 1.7e-88 297.3 0.0 3.7e-38 131.4 0.0 4.7 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.25 EEQ34799.1 - 8.1e-15 54.9 0.0 6.7e-08 32.8 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ34799.1 - 4.6e-06 27.5 0.0 0.16 12.9 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Cys_Met_Meta_PP PF01053.20 EEQ34800.1 - 2.5e-115 385.0 0.0 1.3e-97 326.7 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEQ34800.1 - 8.9e-13 48.1 0.0 1.4e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ34800.1 - 6.8e-10 38.4 0.1 1.2e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ34800.1 - 4.9e-08 32.7 0.0 8.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EEQ34800.1 - 1.7e-06 27.6 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 EEQ34800.1 - 0.002 17.1 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 EEQ34800.1 - 0.03 12.9 1.3 0.39 9.2 1.3 2.1 1 1 0 1 1 1 0 Methionine gamma-lyase PQ-loop PF04193.14 EEQ34801.1 - 1.5e-33 114.3 10.5 9.9e-18 63.7 2.9 2.7 2 0 0 2 2 2 2 PQ loop repeat PTR2 PF00854.21 EEQ34802.1 - 1.8e-63 214.8 6.7 4.2e-63 213.5 6.7 1.5 1 1 0 1 1 1 1 POT family ATPgrasp_N PF18130.1 EEQ34803.1 - 2.6e-14 53.5 0.1 7.6e-14 52.0 0.1 1.9 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EEQ34803.1 - 7.4e-12 45.2 0.0 1.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 EEQ34803.1 - 0.00021 21.4 0.0 0.11 12.6 0.0 2.8 2 0 0 2 2 2 2 L-amino acid ligase C-terminal domain 2 Dala_Dala_lig_C PF07478.13 EEQ34803.1 - 0.0017 17.9 0.0 0.018 14.6 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EEQ34803.1 - 0.017 15.2 0.0 0.09 12.8 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain RNase_Zc3h12a PF11977.8 EEQ34803.1 - 0.02 14.7 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Fungal_trans PF04082.18 EEQ34804.1 - 1.4e-10 40.7 0.0 2.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.7 EEQ34807.1 - 1.7e-24 86.2 3.6 3.7e-14 53.1 0.5 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEQ34807.1 - 2e-15 55.3 3.2 0.00036 20.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EEQ34807.1 - 6.8e-15 55.2 3.1 4.1e-08 33.6 0.3 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ34807.1 - 5e-12 45.8 2.6 5.9e-06 26.5 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EEQ34807.1 - 9.5e-12 44.8 8.4 0.00048 20.5 0.6 3.3 3 0 0 3 3 3 3 Ankyrin repeat Abhydrolase_1 PF00561.20 EEQ34808.1 - 6.4e-31 107.9 0.0 9.9e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ34808.1 - 4.3e-09 37.3 1.6 1.5e-08 35.5 1.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ34808.1 - 0.00043 19.6 0.5 0.013 14.8 0.5 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EEQ34808.1 - 0.0029 17.7 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein PGAP1 PF07819.13 EEQ34808.1 - 0.018 14.8 0.2 0.034 13.9 0.2 1.4 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 EEQ34808.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase VSG_B PF13206.6 EEQ34809.1 - 0.32 10.2 0.7 5.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Trypanosomal VSG domain HisKA_3 PF07730.13 EEQ34809.1 - 0.44 11.1 2.1 7.4 7.2 0.0 3.4 3 2 2 5 5 5 0 Histidine kinase CBF PF03914.17 EEQ34810.1 - 3.2e-36 124.9 0.3 7.7e-36 123.7 0.3 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Fer4_14 PF13394.6 EEQ34810.1 - 0.0014 18.8 0.0 0.045 13.9 0.0 2.8 1 1 1 2 2 2 1 4Fe-4S single cluster domain PRO8NT PF08082.11 EEQ34810.1 - 0.0034 17.3 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain DUF4806 PF16064.5 EEQ34810.1 - 0.1 12.9 0.2 0.55 10.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) LemA PF04011.12 EEQ34810.1 - 0.11 12.4 0.2 0.29 11.0 0.1 1.7 2 0 0 2 2 2 0 LemA family Mt_ATP-synt_B PF05405.14 EEQ34811.1 - 5.7e-49 165.9 8.6 7e-49 165.6 8.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Pkinase PF00069.25 EEQ34812.1 - 4.4e-22 78.7 0.0 1.8e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34812.1 - 1.6e-11 44.0 0.0 1.8e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Sel1 PF08238.12 EEQ34813.1 - 3e-15 56.3 7.5 4.9e-06 27.0 0.9 3.6 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.6 EEQ34813.1 - 0.01 16.4 2.6 0.29 11.8 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat VPS9 PF02204.18 EEQ34814.1 - 2.9e-28 98.1 0.0 5.2e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.25 EEQ34815.1 - 1e-05 25.4 0.1 2.4e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 EEQ34815.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 EEQ34815.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EEQ34815.1 - 0.17 11.5 0.7 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_6 PF12697.7 EEQ34815.1 - 0.67 10.5 3.9 0.46 11.0 2.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAS_3 PF08447.12 EEQ34816.1 - 5.1e-13 49.1 0.0 3.4e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 EEQ34816.1 - 3e-05 24.1 0.0 6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 EEQ34816.1 - 0.00075 19.7 0.0 0.067 13.5 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EEQ34816.1 - 0.0026 17.7 0.0 0.57 10.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold DUF3419 PF11899.8 EEQ34817.1 - 3.8e-150 500.4 0.0 6.1e-150 499.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 EEQ34817.1 - 7.8e-07 29.7 0.0 3.1e-06 27.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ34817.1 - 1.4e-05 25.8 0.0 5.9e-05 23.7 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ34817.1 - 1.7e-05 24.6 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ34817.1 - 0.00011 22.8 0.0 0.00043 20.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ34817.1 - 0.00064 19.1 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Acetyltransf_10 PF13673.7 EEQ34818.1 - 5e-09 36.2 0.0 7.3e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ34818.1 - 8e-09 35.8 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ34818.1 - 1.1e-08 35.4 0.1 1.7e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEQ34818.1 - 0.00023 21.2 0.0 0.0007 19.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain A_deaminase PF00962.22 EEQ34819.1 - 6.2e-27 94.8 0.0 9.9e-27 94.1 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase BTB PF00651.31 EEQ34820.1 - 5.2e-14 52.4 0.1 9.7e-13 48.3 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain Pkinase PF00069.25 EEQ34821.1 - 5e-07 29.3 0.0 1.8e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34821.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Sharpin_PH PF16764.5 EEQ34821.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Sharpin PH domain adh_short PF00106.25 EEQ34822.1 - 1.2e-30 106.5 0.3 1.8e-30 105.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ34822.1 - 4e-27 95.3 0.2 5e-27 95.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ34822.1 - 2.3e-11 43.9 0.2 2.8e-11 43.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ34822.1 - 3.3e-05 23.5 0.0 5.4e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ34822.1 - 0.00023 20.3 0.1 0.00037 19.6 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EEQ34822.1 - 0.00037 20.0 0.2 0.0032 16.9 0.2 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EEQ34822.1 - 0.0068 16.3 0.7 0.012 15.5 0.7 1.5 1 1 0 1 1 1 1 NAD(P)H-binding ECH_1 PF00378.20 EEQ34824.1 - 2e-78 263.2 0.0 2.3e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EEQ34824.1 - 6.2e-37 127.8 0.6 4.5e-34 118.4 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 EEQ34825.1 - 7.2e-79 263.5 4.8 8.3e-79 263.3 4.8 1.0 1 0 0 1 1 1 1 Rer1 family MFS_1 PF07690.16 EEQ34825.1 - 0.0039 16.2 4.1 0.0051 15.8 4.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1538 PF07556.11 EEQ34825.1 - 0.078 12.3 3.8 0.43 9.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) DUF4131 PF13567.6 EEQ34825.1 - 3.5 7.2 8.9 5.9 6.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PolyA_pol PF01743.20 EEQ34826.1 - 5.2e-11 43.1 0.0 6.8e-10 39.5 0.0 2.4 1 1 0 1 1 1 1 Poly A polymerase head domain Catalase PF00199.19 EEQ34827.1 - 2.6e-178 593.0 0.1 5.1e-178 592.0 0.1 1.4 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EEQ34827.1 - 2.8e-12 46.7 0.0 7.4e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Ureidogly_lyase PF04115.12 EEQ34828.1 - 1.3e-50 171.8 0.0 1.7e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase MutS_V PF00488.21 EEQ34829.1 - 6e-72 241.6 0.0 1e-71 240.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EEQ34829.1 - 2.1e-44 152.0 5.6 4.3e-44 151.0 5.6 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EEQ34829.1 - 5e-22 78.3 0.0 1.2e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EEQ34829.1 - 1.4e-07 31.9 0.0 7.8e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 EEQ34829.1 - 9.1e-05 23.1 0.4 0.33 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EEQ34829.1 - 0.037 13.8 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EEQ34829.1 - 0.078 13.0 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EEQ34829.1 - 0.097 12.3 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sec63 PF02889.16 EEQ34830.1 - 3.7e-164 544.1 0.2 3.1e-93 311.6 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EEQ34830.1 - 2.6e-46 157.6 0.0 7.1e-28 97.5 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EEQ34830.1 - 7.4e-30 103.4 0.2 3e-29 101.4 0.2 2.2 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EEQ34830.1 - 1.3e-22 80.6 0.0 7.6e-13 48.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ34830.1 - 2.4e-10 40.8 0.0 1.2e-07 32.1 0.0 3.6 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EEQ34830.1 - 5.4e-06 26.7 0.1 0.0035 17.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 EEQ34830.1 - 0.0015 18.0 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EEQ34830.1 - 0.019 14.0 0.0 1.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 EEQ34830.1 - 0.026 14.9 0.2 19 5.6 0.1 3.5 3 1 0 3 3 3 0 AAA domain Peptidase_S9 PF00326.21 EEQ34831.1 - 2.6e-18 66.3 0.0 6.7e-16 58.4 0.0 2.8 2 1 1 3 3 3 2 Prolyl oligopeptidase family AXE1 PF05448.12 EEQ34831.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HTH_6 PF01418.17 EEQ34832.1 - 0.045 13.7 0.0 0.47 10.5 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_23 PF13384.6 EEQ34832.1 - 0.047 13.5 0.5 0.074 12.9 0.5 1.4 1 0 0 1 1 1 0 Homeodomain-like domain MRP-L28 PF09812.9 EEQ34832.1 - 0.11 12.7 1.5 0.15 12.2 1.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 RTC_insert PF05189.13 EEQ34833.1 - 7.3e-30 103.5 0.0 1.4e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EEQ34833.1 - 5.5e-28 97.7 0.1 6.8e-28 97.4 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase 3-HAO PF06052.12 EEQ34834.1 - 5.8e-56 188.3 0.0 6.8e-56 188.1 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EEQ34834.1 - 6.6e-05 22.5 0.1 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EEQ34834.1 - 0.019 14.9 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain DZR PF12773.7 EEQ34834.1 - 0.026 14.5 0.1 0.071 13.1 0.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.16 EEQ34834.1 - 0.34 10.8 1.9 15 5.6 0.2 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit CAP_GLY PF01302.25 EEQ34835.1 - 8.4e-16 57.7 0.1 2e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 EEQ34835.1 - 6.3e-06 25.9 15.5 4.9e-05 23.1 0.9 3.0 3 0 0 3 3 3 2 CLIP1 zinc knuckle Fez1 PF06818.15 EEQ34835.1 - 0.0012 19.3 22.5 0.08 13.4 14.4 3.0 2 1 1 3 3 3 2 Fez1 HMMR_N PF15905.5 EEQ34835.1 - 0.068 12.6 24.3 1.8 8.0 0.3 2.5 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 EEQ34835.1 - 0.11 11.4 27.4 1.5 7.6 7.1 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 EEQ34835.1 - 0.23 11.5 13.4 0.4 10.7 2.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 EEQ34835.1 - 0.93 8.8 13.4 0.73 9.1 5.7 2.6 2 1 0 2 2 2 0 FAM76 protein DUF745 PF05335.13 EEQ34835.1 - 1.2 8.8 12.9 0.2 11.3 2.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF745) EzrA PF06160.12 EEQ34835.1 - 2.2 6.3 18.9 0.91 7.6 4.0 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA DUF641 PF04859.12 EEQ34835.1 - 3.5 8.0 17.4 0.86 9.9 0.4 3.7 2 2 2 4 4 4 0 Plant protein of unknown function (DUF641) AAA_13 PF13166.6 EEQ34835.1 - 4.9 5.7 15.4 0.5 8.9 7.0 2.1 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.12 EEQ34835.1 - 7.3 7.1 13.4 46 4.6 0.2 4.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 EEQ34835.1 - 7.7 6.4 10.0 1.6 8.6 2.9 2.4 2 0 0 2 2 2 0 Sec34-like family SlyX PF04102.12 EEQ34835.1 - 7.9 7.2 24.8 1.2 9.8 0.4 3.9 3 1 0 3 3 3 0 SlyX CASP_C PF08172.12 EEQ34835.1 - 7.9 5.7 11.1 2.2 7.5 0.1 3.3 2 1 0 3 3 3 0 CASP C terminal Pkinase PF00069.25 EEQ34836.1 - 5.2e-35 121.1 0.0 1.1e-19 70.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34836.1 - 8.3e-12 44.9 0.0 5.6e-09 35.7 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEQ34836.1 - 0.0026 17.1 0.0 0.64 9.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EEQ34836.1 - 0.0081 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3632 PF12311.8 EEQ34837.1 - 1.9e-10 41.5 0.0 3.2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF3632 PF12311.8 EEQ34838.1 - 1.1e-10 42.2 0.0 1.5e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Pkinase_Tyr PF07714.17 EEQ34839.1 - 3.5e-14 52.7 0.0 5.5e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EEQ34839.1 - 9.9e-11 41.5 0.0 8.1e-09 35.2 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 EEQ34839.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ34839.1 - 0.062 13.2 0.1 0.21 11.5 0.1 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ34839.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase OPT PF03169.15 EEQ34840.1 - 4.6e-87 293.1 46.3 5.3e-87 292.9 46.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PetL PF05115.14 EEQ34840.1 - 0.056 13.4 0.1 0.056 13.4 0.1 3.7 4 0 0 4 4 4 0 Cytochrome B6-F complex subunit VI (PetL) PWWP PF00855.17 EEQ34841.1 - 7.4e-16 58.3 8.8 2.5e-14 53.4 8.8 3.3 1 1 0 1 1 1 1 PWWP domain ComA PF02679.15 EEQ34842.1 - 6.8e-59 199.3 0.0 1e-58 198.7 0.0 1.2 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) SpoIIE PF07228.12 EEQ34843.1 - 1.4e-11 44.7 0.1 6e-10 39.3 0.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EEQ34843.1 - 3.6e-07 30.0 0.2 7.5e-07 29.0 0.2 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EEQ34843.1 - 6.1e-06 26.1 0.1 0.0027 17.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C WD40 PF00400.32 EEQ34844.1 - 3.6e-34 116.2 21.9 2e-07 31.6 0.5 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat PRP4 PF08799.11 EEQ34844.1 - 2.3e-14 52.7 0.9 4.3e-14 51.7 0.9 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EEQ34844.1 - 1.4e-11 44.5 0.0 0.014 15.7 0.0 5.6 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EEQ34844.1 - 0.0087 15.4 0.0 0.39 10.0 0.0 2.5 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EEQ34844.1 - 0.019 14.3 0.0 0.31 10.3 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain F-box-like PF12937.7 EEQ34845.1 - 0.00029 20.6 0.6 0.00029 20.6 0.6 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EEQ34845.1 - 0.024 14.5 1.0 0.024 14.5 1.0 1.9 2 0 0 2 2 2 0 F-box domain Ku PF02735.16 EEQ34845.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain ATP-synt_D PF01813.17 EEQ34845.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 ATP synthase subunit D HSCB_C PF07743.13 EEQ34847.1 - 5.9e-20 71.6 0.5 2.5e-19 69.5 0.2 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EEQ34847.1 - 5.3e-06 26.5 0.1 2.3e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain SHD1 PF03983.12 EEQ34849.1 - 8e-33 112.1 0.0 1.5e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 EEQ34849.1 - 4.6e-31 106.2 6.2 8.3e-12 44.5 0.2 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EEQ34849.1 - 6e-29 99.7 6.4 2e-11 43.6 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 EEQ34849.1 - 9.6e-20 70.0 0.3 1.8e-08 33.9 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 EEQ34849.1 - 5.1e-05 23.2 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 EEQ34849.1 - 0.037 14.1 1.3 1.9 8.6 0.0 3.4 4 0 0 4 4 4 0 SH3 domain SH3_3 PF08239.11 EEQ34849.1 - 1.1 9.5 4.0 3.8 7.8 0.6 3.0 3 0 0 3 3 3 0 Bacterial SH3 domain PRKCSH PF07915.13 EEQ34850.1 - 1.1e-17 64.8 0.1 1.1e-17 64.8 0.1 2.8 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein Coilin_N PF15862.5 EEQ34850.1 - 0.00071 19.4 3.7 0.0039 17.0 0.0 3.3 2 1 1 3 3 3 1 Coilin N-terminus STT3 PF02516.14 EEQ34851.1 - 3.4e-146 488.0 35.2 2.1e-140 468.9 34.3 2.4 3 0 0 3 3 3 2 Oligosaccharyl transferase STT3 subunit SNN_transmemb PF09049.10 EEQ34852.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Stannin transmembrane APH PF01636.23 EEQ34853.1 - 3e-18 66.6 0.0 5.6e-18 65.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ34853.1 - 3e-05 23.5 0.0 0.25 10.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEQ34853.1 - 0.002 17.8 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 EEQ34853.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EEQ34853.1 - 0.016 14.8 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 EEQ34853.1 - 0.058 12.7 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pirin PF02678.16 EEQ34854.1 - 1.5e-30 105.3 0.1 3e-30 104.4 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EEQ34854.1 - 1e-25 90.1 0.0 3.1e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EEQ34854.1 - 0.00014 21.5 1.8 0.0031 17.2 1.2 2.4 2 1 0 2 2 2 1 Cupin domain PMT PF02366.18 EEQ34855.1 - 3.3e-85 285.6 14.9 5.4e-85 284.9 14.9 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EEQ34855.1 - 1.9e-70 236.5 1.6 1.9e-70 236.5 1.6 2.8 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EEQ34855.1 - 7.7e-20 71.5 0.4 1.5e-19 70.6 0.4 1.4 1 0 0 1 1 1 1 MIR domain DUF2516 PF10724.9 EEQ34855.1 - 0.33 11.3 2.4 11 6.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) PMT_2 PF13231.6 EEQ34855.1 - 0.66 10.2 15.9 0.021 15.0 7.1 3.0 3 1 1 4 4 4 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Caps_synth_CapC PF14102.6 EEQ34855.1 - 3.2 8.2 9.1 76 3.8 6.5 3.5 2 1 0 2 2 2 0 Capsule biosynthesis CapC WD40 PF00400.32 EEQ34857.1 - 4.2e-05 24.2 8.5 2.2 9.3 0.1 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat NUDE_C PF04880.13 EEQ34857.1 - 0.45 11.0 8.8 0.053 14.0 2.0 2.7 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region ATP-synt_E PF05680.12 EEQ34858.1 - 2.2e-22 79.2 0.4 2.3e-22 79.1 0.4 1.0 1 0 0 1 1 1 1 ATP synthase E chain Tli4_N PF18443.1 EEQ34858.1 - 0.038 14.4 0.1 0.045 14.1 0.1 1.1 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain CSN8_PSD8_EIF3K PF10075.9 EEQ34859.1 - 4.7e-21 75.3 0.0 7.7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 EEQ34859.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 PCI domain DUF3453 PF11935.8 EEQ34860.1 - 4.4e-68 229.3 1.9 4.4e-68 229.3 1.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) DUF4404 PF14357.6 EEQ34860.1 - 0.056 14.1 0.2 0.47 11.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Coiled-coil_56 PF09813.9 EEQ34861.1 - 0.001 19.1 0.0 0.001 19.1 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Sds3 PF08598.11 EEQ34862.1 - 1.2e-12 48.4 0.9 1.2e-12 48.4 0.9 2.1 2 1 0 2 2 2 1 Sds3-like BUD22 PF09073.10 EEQ34863.1 - 0.02 14.3 29.8 0.025 13.9 29.8 1.3 1 0 0 1 1 1 0 BUD22 GREB1 PF15782.5 EEQ34863.1 - 7.4 3.5 14.2 8.5 3.3 14.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GPI-anchored PF10342.9 EEQ34864.1 - 5.2e-07 30.3 0.1 5.2e-07 30.3 0.1 2.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GREB1 PF15782.5 EEQ34864.1 - 4.3 4.3 5.6 4.8 4.2 5.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 EEQ34864.1 - 4.5 6.4 22.2 5.2 6.2 22.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein GCOM2 PF15328.6 EEQ34864.1 - 9 6.6 10.0 12 6.2 10.0 1.1 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 NUFIP1 PF10453.9 EEQ34865.1 - 4e-08 33.0 13.2 4e-08 33.0 13.2 2.7 1 1 1 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 EEQ34865.1 - 5.9e-08 32.4 4.8 9.7e-08 31.7 4.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ34865.1 - 1.5e-05 24.8 4.3 2.5e-05 24.1 4.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EEQ34865.1 - 0.0041 16.9 3.8 0.0065 16.3 3.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger FapA PF03961.13 EEQ34865.1 - 5.2 5.6 10.0 7.3 5.1 10.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A RNA_pol_Rbc25 PF08292.12 EEQ34866.1 - 1.6e-34 118.9 1.9 1.1e-33 116.3 1.9 2.0 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EEQ34866.1 - 3.3e-11 43.4 0.1 9.7e-11 41.9 0.1 1.8 1 1 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 APH PF01636.23 EEQ34867.1 - 1.6e-18 67.5 0.2 8.6e-10 38.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ34867.1 - 6e-10 39.1 0.1 3e-08 33.5 0.2 2.2 1 1 1 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ34867.1 - 5.6e-07 29.2 0.0 5.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Fructosamin_kin PF03881.14 EEQ34867.1 - 1.3e-06 27.8 0.0 2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.22 EEQ34867.1 - 0.0035 16.9 0.2 0.47 10.0 0.0 2.4 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 EEQ34867.1 - 0.014 14.3 0.0 0.28 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase_Tyr PF07714.17 EEQ34867.1 - 0.06 12.6 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Cys_Met_Meta_PP PF01053.20 EEQ34868.1 - 2.5e-136 454.2 0.0 2.9e-136 454.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEQ34868.1 - 1.5e-07 31.0 0.1 2.1e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ34868.1 - 0.0056 15.7 0.1 0.01 14.9 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ34868.1 - 0.0083 15.5 0.4 0.02 14.2 0.4 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EEQ34868.1 - 0.035 13.4 0.0 0.058 12.7 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Crinivirus_P26 PF07416.11 EEQ34868.1 - 0.05 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Crinivirus P26 protein Peptidase_M36 PF02128.15 EEQ34869.1 - 8.2e-153 508.9 2.0 1.1e-152 508.6 2.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EEQ34869.1 - 1.2e-17 63.4 2.7 2.6e-17 62.4 2.7 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EEQ34869.1 - 0.034 14.0 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Methyltransf_16 PF10294.9 EEQ34872.1 - 0.0041 16.9 0.0 0.058 13.1 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase NAD_binding_6 PF08030.12 EEQ34872.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.7 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Methyltransf_31 PF13847.6 EEQ34872.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Wound_ind PF08186.11 EEQ34872.1 - 0.23 11.9 1.3 0.55 10.7 1.3 1.6 1 0 0 1 1 1 0 Wound-inducible basic protein family Filament PF00038.21 EEQ34874.1 - 6.4e-05 22.7 48.8 6.4e-05 22.7 48.8 2.9 2 1 1 3 3 3 2 Intermediate filament protein Muted PF14942.6 EEQ34874.1 - 0.013 15.9 2.0 0.013 15.9 2.0 6.3 6 1 0 7 7 7 0 Organelle biogenesis, Muted-like protein FOXP-CC PF16159.5 EEQ34876.1 - 0.024 15.3 1.3 0.024 15.3 1.3 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 EEQ34876.1 - 0.16 12.4 17.2 0.096 13.2 0.5 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF629 PF04780.12 EEQ34876.1 - 1.5 7.3 6.4 0.8 8.2 4.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Peptidase_S8 PF00082.22 EEQ34877.1 - 4.6e-24 85.2 10.0 9.8e-24 84.1 9.6 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ34877.1 - 6e-12 46.1 0.0 9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 zf-C2H2 PF00096.26 EEQ34879.1 - 6.9e-07 29.4 40.3 0.008 16.6 2.7 6.9 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EEQ34879.1 - 0.0047 17.2 13.7 0.095 13.0 0.4 4.8 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EEQ34879.1 - 0.021 15.7 43.4 0.42 11.6 2.1 7.0 7 0 0 7 7 7 0 C2H2-type zinc finger Carb_kinase PF01256.17 EEQ34880.1 - 2.1e-51 174.7 0.3 5.7e-50 170.1 0.1 2.0 2 0 0 2 2 2 2 Carbohydrate kinase SPT2 PF08243.11 EEQ34881.1 - 6e-11 42.9 13.0 6e-11 42.9 13.0 2.0 2 0 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 EEQ34882.1 - 1.1e-26 93.2 10.1 1.3e-26 93.0 10.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBA_6 PF18039.1 EEQ34882.1 - 0.033 14.1 0.2 0.071 13.0 0.0 1.6 2 0 0 2 2 2 0 UBA-like domain EF-hand_14 PF17959.1 EEQ34882.1 - 0.039 14.3 0.0 0.056 13.8 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain Ribosomal_S19 PF00203.21 EEQ34883.1 - 5.4e-33 112.7 0.3 7.4e-33 112.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SET PF00856.28 EEQ34884.1 - 2.3e-14 54.1 0.0 6.5e-14 52.7 0.0 1.8 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 EEQ34884.1 - 7.3e-09 35.6 5.7 7.3e-09 35.6 5.7 2.2 2 0 0 2 2 2 1 MYND finger CPSase_L_D2 PF02786.17 EEQ34886.1 - 1e-107 358.5 0.0 2.2e-83 278.9 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EEQ34886.1 - 3.7e-41 140.3 0.0 1.1e-40 138.8 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EEQ34886.1 - 4.5e-17 62.1 0.0 2.6e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EEQ34886.1 - 1.8e-15 57.0 0.0 5.7e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EEQ34886.1 - 2.2e-12 46.9 0.0 0.00012 21.8 0.0 3.1 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 EEQ34886.1 - 2.1e-05 24.1 0.0 0.02 14.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EEQ34886.1 - 0.011 15.5 0.0 0.51 10.1 0.0 2.5 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MGS PF02142.22 EEQ34886.1 - 0.017 15.3 0.0 0.081 13.1 0.0 2.2 2 0 0 2 2 2 0 MGS-like domain HNH_2 PF13391.6 EEQ34887.1 - 1.9e-18 66.4 0.0 3.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HC2 PF07382.11 EEQ34888.1 - 0.012 15.8 1.6 0.019 15.1 1.6 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DUF4187 PF13821.6 EEQ34889.1 - 5.3e-22 77.4 2.8 1.4e-21 76.0 2.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EEQ34889.1 - 1.4e-07 31.3 4.7 6.3e-07 29.2 3.5 2.6 2 1 0 2 2 2 1 G-patch domain Phage_tail_L PF05100.12 EEQ34889.1 - 0.095 12.0 0.2 0.19 11.0 0.2 1.5 1 0 0 1 1 1 0 Phage minor tail protein L PALP PF00291.25 EEQ34890.1 - 1.7e-39 136.0 0.1 2.1e-39 135.7 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CDP-OH_P_transf PF01066.21 EEQ34891.1 - 2e-15 57.3 0.1 2e-15 57.3 0.1 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M1_N PF17900.1 EEQ34892.1 - 0.0018 18.5 0.3 0.98 9.6 0.1 2.7 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EEQ34892.1 - 0.0048 16.5 0.0 0.022 14.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M1 domain LSM PF01423.22 EEQ34893.1 - 7.1e-18 64.1 0.7 2.9e-10 39.7 0.2 2.1 2 0 0 2 2 2 2 LSM domain LtrA PF06772.11 EEQ34894.1 - 3.2e-15 56.2 28.8 7.5e-09 35.3 3.1 3.1 2 1 1 3 3 3 3 Bacterial low temperature requirement A protein (LtrA) zf-C4H2 PF10146.9 EEQ34894.1 - 0.12 12.7 0.2 0.12 12.7 0.2 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein Met_asp_mut_E PF06368.11 EEQ34894.1 - 0.2 10.1 0.2 0.31 9.5 0.2 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Spc24 PF08286.11 EEQ34894.1 - 4.6 7.5 8.7 0.39 11.0 1.4 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 adh_short PF00106.25 EEQ34895.1 - 2.1e-28 99.1 0.9 8.4e-19 67.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ34895.1 - 7.8e-22 78.0 0.2 7e-17 61.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ34895.1 - 0.00029 20.8 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EEQ34895.1 - 0.074 12.8 0.3 5.1 6.9 0.3 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 EEQ34895.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ketoacyl-synt PF00109.26 EEQ34896.1 - 2.6e-69 233.6 0.0 6.8e-69 232.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EEQ34896.1 - 8.6e-51 172.9 0.0 1.4e-50 172.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EEQ34896.1 - 1.4e-49 168.4 0.3 3.1e-49 167.3 0.3 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EEQ34896.1 - 1.3e-45 156.3 0.5 2.9e-45 155.2 0.5 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ34896.1 - 5.1e-32 110.4 0.1 1.6e-31 108.7 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EEQ34896.1 - 1.6e-13 51.1 0.0 4.1e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EEQ34896.1 - 1.2e-08 35.1 0.0 6.4e-08 32.8 0.0 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EEQ34896.1 - 6.4e-07 29.0 0.1 1.5e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ34896.1 - 1.1e-05 25.1 0.0 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 EEQ34896.1 - 1.6e-05 24.8 0.0 6.4e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 EEQ34896.1 - 0.0004 19.8 0.0 0.00092 18.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.6 EEQ34896.1 - 0.019 16.0 0.0 0.067 14.2 0.0 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FSH1 PF03959.13 EEQ34897.1 - 1.6e-23 83.5 0.0 6.4e-23 81.5 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EEQ34897.1 - 0.018 14.8 0.8 0.093 12.5 0.2 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 EEQ34897.1 - 0.035 13.7 0.1 0.075 12.6 0.0 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) p450 PF00067.22 EEQ34899.1 - 8.7e-64 216.0 0.0 1.8e-63 215.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Chal_sti_synt_C PF02797.15 EEQ34900.1 - 1.1e-17 64.4 0.0 2.1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EEQ34900.1 - 9.9e-16 57.8 0.0 1.4e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.10 EEQ34900.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EEQ34900.1 - 0.5 10.3 2.3 3.5 7.6 2.3 2.2 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cyt-b5 PF00173.28 EEQ34901.1 - 2.1e-10 40.6 0.0 6.1e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Prok-E2_E PF14462.6 EEQ34901.1 - 0.16 11.8 0.6 0.25 11.1 0.6 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E RPN7 PF10602.9 EEQ34903.1 - 2.5e-47 160.8 0.1 4.3e-47 160.0 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EEQ34903.1 - 5.9e-11 42.8 0.1 3.6e-10 40.3 0.1 2.4 2 0 0 2 2 2 1 PCI domain TMEM237 PF15383.6 EEQ34903.1 - 0.092 11.8 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 zf-C2H2 PF00096.26 EEQ34904.1 - 0.0095 16.4 26.2 0.6 10.7 1.0 5.3 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ34904.1 - 0.15 13.0 22.1 1.1 10.3 0.6 5.5 5 1 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.7 EEQ34904.1 - 0.32 11.4 1.3 6.4 7.3 0.5 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 EEQ34904.1 - 2.4 8.8 5.3 31 5.3 0.5 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain ATP_transf PF09830.9 EEQ34906.1 - 1.7e-24 85.8 0.1 2.9e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 EEQ34906.1 - 0.13 11.6 0.0 0.35 10.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4931) Myb_DNA-bind_4 PF13837.6 EEQ34907.1 - 0.099 13.0 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Auto_anti-p27 PF06677.12 EEQ34907.1 - 0.13 12.5 0.5 0.31 11.2 0.5 1.7 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MFS_1 PF07690.16 EEQ34908.1 - 7.6e-21 74.4 30.7 3.7e-10 39.3 6.8 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 EEQ34908.1 - 2.7e-08 32.9 0.9 0.00035 19.4 0.0 2.9 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 EEQ34908.1 - 8.5e-06 24.9 3.9 0.36 9.6 0.2 3.3 3 0 0 3 3 3 3 MFS_1 like family MFS_2 PF13347.6 EEQ34908.1 - 0.00034 19.3 5.2 0.00034 19.3 5.2 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein LacY_symp PF01306.19 EEQ34908.1 - 1.1 8.0 14.2 0.02 13.7 1.5 3.2 4 0 0 4 4 4 0 LacY proton/sugar symporter zf-rbx1 PF12678.7 EEQ34909.1 - 8.1e-09 35.6 3.7 1.9e-08 34.5 3.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEQ34909.1 - 8e-08 32.5 3.1 8e-08 32.5 3.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EEQ34909.1 - 3.8e-07 29.9 1.7 7.5e-07 28.9 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ34909.1 - 2.3e-06 27.4 4.8 1.6e-05 24.6 1.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ34909.1 - 4.4e-05 23.4 1.7 9.8e-05 22.3 1.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EEQ34909.1 - 8.1e-05 22.4 3.3 8.1e-05 22.4 3.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEQ34909.1 - 0.00029 20.4 0.7 0.0006 19.4 0.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EEQ34909.1 - 0.0012 18.7 4.6 0.016 15.2 5.3 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ34909.1 - 0.002 18.0 0.6 0.002 18.0 0.6 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EEQ34909.1 - 0.0044 17.1 4.9 0.035 14.1 4.9 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger YacG PF03884.14 EEQ34909.1 - 0.031 14.0 0.5 0.079 12.7 0.5 1.7 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG zf-RING_11 PF17123.5 EEQ34909.1 - 0.1 12.4 2.1 0.75 9.6 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger CNDH2_M PF16869.5 EEQ34909.1 - 0.1 13.3 12.8 0.12 13.0 10.2 2.4 2 1 0 2 2 2 0 PF16858 ATP-synt_C PF00137.21 EEQ34909.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 ATP synthase subunit C TarH PF02203.15 EEQ34909.1 - 0.2 11.6 2.0 0.36 10.7 0.1 2.0 2 0 0 2 2 2 0 Tar ligand binding domain homologue CDC27 PF09507.10 EEQ34909.1 - 0.31 10.4 15.2 0.57 9.5 15.2 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C3HC4_4 PF15227.6 EEQ34909.1 - 0.38 11.0 1.4 0.8 9.9 1.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EEQ34909.1 - 0.68 10.3 1.9 1.2 9.5 1.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EEQ34909.1 - 1.5 8.7 3.7 0.73 9.7 1.0 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PPP4R2 PF09184.11 EEQ34909.1 - 2.3 7.7 14.2 4.1 6.9 14.2 1.3 1 0 0 1 1 1 0 PPP4R2 FAM176 PF14851.6 EEQ34909.1 - 9.3 5.9 7.5 28 4.3 7.5 1.8 1 0 0 1 1 1 0 FAM176 family SurE PF01975.17 EEQ34910.1 - 9.1e-37 126.7 0.2 1.2e-36 126.3 0.2 1.2 1 0 0 1 1 1 1 Survival protein SurE DUF3431 PF11913.8 EEQ34911.1 - 6e-89 297.5 0.0 1e-88 296.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) ScsC_N PF18312.1 EEQ34912.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain DnaJ PF00226.31 EEQ34914.1 - 2.3e-21 75.7 1.3 2.3e-21 75.7 1.3 2.4 2 0 0 2 2 2 1 DnaJ domain MLD PF11647.8 EEQ34914.1 - 0.067 13.5 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Membrane Localization Domain RicinB_lectin_2 PF14200.6 EEQ34916.1 - 0.1 13.4 0.0 3.1 8.6 0.0 2.3 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like APH PF01636.23 EEQ34920.1 - 9.6e-06 25.7 8.3 2.2e-05 24.5 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EEQ34920.1 - 0.00012 21.6 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EEQ34920.1 - 0.00056 19.3 0.5 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEQ34920.1 - 0.032 13.0 0.6 0.11 11.2 0.0 2.1 3 0 0 3 3 3 0 Fungal protein kinase HSDR_N_2 PF13588.6 EEQ34920.1 - 0.086 12.8 0.1 8.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) tRNA-synt_1 PF00133.22 EEQ34922.1 - 7.2e-221 734.6 0.3 7.8e-220 731.2 0.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EEQ34922.1 - 6.4e-34 117.1 1.1 6.4e-34 117.1 1.1 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EEQ34922.1 - 3.6e-15 55.6 0.5 5.4e-07 28.7 0.0 4.6 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EEQ34922.1 - 2e-08 34.0 5.5 1.7e-05 24.4 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EEQ34922.1 - 0.0017 17.7 0.0 0.21 10.9 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain PepSY PF03413.19 EEQ34922.1 - 0.077 13.6 1.3 0.15 12.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Pkinase PF00069.25 EEQ34923.1 - 3.2e-64 216.8 0.1 3.8e-64 216.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34923.1 - 5.2e-19 68.5 0.0 7.2e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ34923.1 - 7.8e-09 35.8 0.1 0.00012 22.1 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEQ34923.1 - 0.0035 16.2 0.1 0.0089 14.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EEQ34923.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EEQ34923.1 - 0.033 13.8 0.6 0.071 12.7 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 EEQ34923.1 - 0.049 13.0 0.5 0.099 12.0 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_P_p30 PF01876.16 EEQ34924.1 - 2e-63 213.7 0.0 2.4e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 F-box PF00646.33 EEQ34925.1 - 4.5e-05 23.2 0.0 9.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EEQ34925.1 - 7e-05 22.6 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like DUF4096 PF13340.6 EEQ34925.1 - 0.18 12.1 0.5 0.68 10.2 0.2 2.2 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) A_deaminase PF00962.22 EEQ34927.1 - 1.4e-122 409.2 0.0 1.8e-122 408.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF676 PF05057.14 EEQ34927.1 - 0.059 12.9 0.7 1.9 8.0 0.0 2.4 1 1 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EEQ34929.1 - 2.8e-20 73.9 0.1 3.4e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ34929.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EEQ34929.1 - 0.02 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.13 EEQ34929.1 - 0.029 14.1 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 EEQ34929.1 - 0.051 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 EEQ34929.1 - 0.091 12.4 0.0 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold FGGY_N PF00370.21 EEQ34930.1 - 4.9e-71 239.1 0.0 6.9e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EEQ34930.1 - 6.3e-71 238.2 1.1 9.4e-71 237.6 0.4 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain MIP PF00230.20 EEQ34931.1 - 2.8e-61 207.2 4.7 3.3e-61 206.9 4.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_S10 PF00450.22 EEQ34934.1 - 1.8e-82 278.0 0.0 2.4e-82 277.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3752 PF12572.8 EEQ34935.1 - 2.2e-46 158.2 14.3 2.2e-46 158.2 14.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) JHY PF15261.6 EEQ34935.1 - 7 7.4 14.0 0.85 10.3 9.2 1.9 2 0 0 2 2 2 0 Jhy protein DSBA PF01323.20 EEQ34936.1 - 0.078 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain tRNA-synt_2c PF01411.19 EEQ34937.1 - 7.6e-218 724.5 0.0 7.6e-218 724.5 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EEQ34937.1 - 5.2e-18 64.9 0.6 1.3e-17 63.5 0.6 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EEQ34937.1 - 1.5e-13 51.4 3.0 1.5e-13 51.4 3.0 2.2 2 0 0 2 2 2 1 DHHA1 domain Pro_isomerase PF00160.21 EEQ34938.1 - 2.6e-50 170.8 0.5 3e-50 170.6 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.6 EEQ34940.1 - 9.2e-13 48.3 6.7 1.5e-12 47.6 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ34940.1 - 2e-09 37.1 6.4 3.3e-09 36.4 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEQ34940.1 - 5.2e-09 35.7 1.2 9.5e-09 34.8 1.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EEQ34940.1 - 3e-08 33.4 4.1 5.1e-08 32.7 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ34940.1 - 1.3e-06 28.2 3.6 2.2e-06 27.5 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EEQ34940.1 - 3.3e-06 27.3 9.9 1.8e-05 24.9 9.9 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEQ34940.1 - 0.00039 20.4 0.8 0.00039 20.4 0.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EEQ34940.1 - 0.0011 18.7 2.7 0.0019 18.0 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EEQ34940.1 - 0.0028 17.7 3.4 0.0082 16.2 3.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EEQ34940.1 - 0.02 14.5 4.3 0.042 13.5 4.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EEQ34940.1 - 0.059 13.2 6.2 0.11 12.3 6.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FAM176 PF14851.6 EEQ34940.1 - 0.075 12.7 0.3 6.7 6.4 0.0 2.9 3 0 0 3 3 3 0 FAM176 family PHD PF00628.29 EEQ34940.1 - 0.093 12.6 6.2 0.18 11.7 6.2 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 EEQ34940.1 - 0.11 12.3 4.6 0.27 11.1 4.6 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 OAD_gamma PF04277.13 EEQ34940.1 - 0.12 13.0 0.0 0.4 11.3 0.0 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-C3HC4_4 PF15227.6 EEQ34940.1 - 0.12 12.6 4.8 0.27 11.4 4.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 EEQ34940.1 - 0.13 12.4 1.4 0.41 10.8 1.4 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger RINGv PF12906.7 EEQ34940.1 - 0.37 10.9 3.9 0.92 9.7 3.9 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EEQ34940.1 - 0.47 10.7 3.9 1.4 9.1 3.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EEQ34940.1 - 1 9.5 4.9 2.8 8.1 4.9 1.7 1 1 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 EEQ34940.1 - 1.8 8.5 8.5 0.077 12.9 1.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3844 PF12955.7 EEQ34941.1 - 4.7e-33 113.5 4.1 7.9e-33 112.7 4.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_alliinase PF04863.13 EEQ34941.1 - 0.4 11.1 6.9 0.87 10.0 4.5 2.3 2 0 0 2 2 2 0 Alliinase EGF-like domain Hce2 PF14856.6 EEQ34944.1 - 0.017 15.4 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor Glyco_transf_54 PF04666.13 EEQ34945.1 - 1.3e-16 60.4 0.0 2.4e-12 46.3 0.0 2.8 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Thioredoxin_4 PF13462.6 EEQ34947.1 - 2.8e-06 27.6 0.0 2.1e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin Phage_TAC_6 PF09550.10 EEQ34947.1 - 0.064 13.7 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC CKS PF01111.19 EEQ34948.1 - 7.1e-35 119.1 1.2 9.7e-35 118.7 1.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 EEQ34949.1 - 6.4e-18 64.6 6.5 2.4e-10 40.3 0.0 3.1 3 0 0 3 3 3 2 Bromodomain APH PF01636.23 EEQ34950.1 - 2.7e-15 56.9 0.0 5.6e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ34950.1 - 0.025 13.4 0.1 0.75 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUP PF00674.18 EEQ34950.1 - 0.065 13.4 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 DUP family Tox-ART-HYD1 PF15633.6 EEQ34950.1 - 0.08 13.6 0.0 0.64 10.7 0.0 2.2 2 0 0 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase Fructosamin_kin PF03881.14 EEQ34950.1 - 0.14 11.3 0.1 0.3 10.2 0.0 1.5 2 0 0 2 2 2 0 Fructosamine kinase Ribosomal_S18 PF01084.20 EEQ34951.1 - 0.082 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S18 DUF3693 PF12472.8 EEQ34952.1 - 0.0054 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Phage related protein HSP70 PF00012.20 EEQ34955.1 - 1.6e-227 756.5 9.2 1.7e-227 756.4 9.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ34955.1 - 3e-16 59.2 0.4 2.5e-15 56.1 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EEQ34955.1 - 6.1e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EEQ34955.1 - 0.019 14.0 0.1 0.3 10.0 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain MscS_porin PF12795.7 EEQ34955.1 - 0.28 10.7 2.6 0.22 11.1 0.4 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4845 PF16137.5 EEQ34955.1 - 2.7 8.9 4.6 6.6 7.7 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4845) RRF PF01765.19 EEQ34956.1 - 6.5e-31 107.5 0.8 8.2e-31 107.1 0.0 1.5 2 0 0 2 2 2 1 Ribosome recycling factor DUF1574 PF07611.11 EEQ34957.1 - 0.052 12.9 0.1 0.07 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) ANAPC_CDC26 PF10471.9 EEQ34958.1 - 8.6e-19 68.1 0.8 1e-18 67.9 0.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Fungal_trans PF04082.18 EEQ34959.1 - 5.5e-07 28.9 0.0 5.5e-07 28.9 0.0 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ34959.1 - 3.2e-05 23.9 8.2 5.8e-05 23.1 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gti1_Pac2 PF09729.9 EEQ34959.1 - 0.38 10.8 6.0 0.3 11.1 2.6 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family EPL1 PF10513.9 EEQ34959.1 - 0.87 10.0 9.3 2 8.8 9.3 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like Spt20 PF12090.8 EEQ34959.1 - 1.5 8.3 29.1 3.2 7.3 29.1 1.4 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 EEQ34959.1 - 2 7.3 9.5 3.2 6.6 9.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.22 EEQ34959.1 - 2.6 7.2 4.3 3.7 6.7 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PBP_sp32 PF07222.12 EEQ34959.1 - 3.9 6.9 14.2 8.3 5.8 14.2 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Neur_chan_memb PF02932.16 EEQ34959.1 - 5 7.1 6.9 12 5.9 6.9 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FeS_assembly_P PF01883.19 EEQ34960.1 - 7.2e-10 38.9 0.0 1.8e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Pheromone PF08015.11 EEQ34960.1 - 3 9.0 0.0 3 9.0 0.0 3.4 3 1 0 3 3 3 0 Fungal mating-type pheromone adh_short_C2 PF13561.6 EEQ34961.1 - 1.2e-50 172.2 0.4 3e-44 151.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ34961.1 - 2.7e-39 134.6 0.4 1.8e-28 99.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 EEQ34961.1 - 4.4e-05 23.1 0.2 0.0007 19.1 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EEQ34961.1 - 7.2e-05 22.8 0.7 0.026 14.4 0.5 2.4 2 1 0 2 2 2 2 KR domain GDP_Man_Dehyd PF16363.5 EEQ34961.1 - 9.8e-05 21.9 0.3 0.0013 18.2 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EEQ34961.1 - 0.00017 21.9 0.2 0.00034 20.9 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EEQ34961.1 - 0.0027 18.0 0.1 0.005 17.1 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 EEQ34961.1 - 0.029 14.3 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EEQ34961.1 - 0.047 12.8 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EEQ34961.1 - 0.07 12.1 0.3 0.1 11.6 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.23 EEQ34961.1 - 0.082 13.0 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EEQ34961.1 - 0.13 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF43 PF01861.16 EEQ34961.1 - 0.16 11.2 0.3 0.27 10.4 0.3 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Chromate_transp PF02417.15 EEQ34962.1 - 5.3e-47 159.9 25.5 3.2e-34 118.3 15.2 3.3 2 1 1 3 3 3 3 Chromate transporter GTP_EFTU PF00009.27 EEQ34963.1 - 9.3e-49 165.6 0.0 1.4e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EEQ34963.1 - 3.6e-37 127.6 9.1 6.3e-37 126.9 9.1 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EEQ34963.1 - 9.5e-21 73.8 0.0 2.8e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EEQ34963.1 - 9.3e-20 70.5 0.0 3.3e-19 68.7 0.0 2.0 2 0 0 2 2 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEQ34963.1 - 8.2e-11 42.1 0.1 2e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EEQ34963.1 - 3.4e-07 30.2 0.1 1.2e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EEQ34963.1 - 2.6e-05 24.3 0.1 5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EEQ34963.1 - 0.035 13.7 0.0 0.097 12.3 0.0 1.9 1 0 0 1 1 1 0 Ras family Septin PF00735.18 EEQ34963.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin DUF5505 PF17610.2 EEQ34963.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) G-alpha PF00503.20 EEQ34963.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.10 EEQ34963.1 - 0.16 11.4 0.1 1.2 8.6 0.1 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit LysM PF01476.20 EEQ34964.1 - 2.5e-18 65.9 0.3 0.00033 20.6 0.0 4.7 4 1 1 5 5 5 4 LysM domain UPF0203 PF05254.12 EEQ34964.1 - 0.00052 20.2 6.9 0.61 10.4 0.1 4.2 4 1 0 4 4 4 3 Uncharacterised protein family (UPF0203) DUF4653 PF15546.6 EEQ34964.1 - 0.0086 15.7 2.0 0.0086 15.7 2.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4653) DUF1153 PF06627.11 EEQ34964.1 - 0.036 14.2 0.0 19 5.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) Rab15_effector PF15208.6 EEQ34964.1 - 0.039 13.3 0.0 0.52 9.6 0.0 2.5 3 0 0 3 3 3 0 Rab15 effector FA_desaturase PF00487.24 EEQ34965.1 - 1.3e-16 61.2 20.5 1.3e-16 61.2 20.5 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EEQ34965.1 - 2.2e-11 43.7 0.0 5.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HsbA PF12296.8 EEQ34966.1 - 6.1e-17 62.2 0.0 8.4e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF1627 PF07789.12 EEQ34966.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) ketoacyl-synt PF00109.26 EEQ34967.1 - 7.7e-63 212.4 0.0 1.5e-62 211.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EEQ34967.1 - 1.4e-62 211.6 0.0 2.1e-62 211.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EEQ34967.1 - 6.2e-62 208.7 0.8 1.5e-59 200.9 0.2 2.7 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EEQ34967.1 - 9.3e-56 189.6 0.0 1.5e-55 188.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EEQ34967.1 - 1.1e-54 185.3 0.0 1.8e-54 184.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EEQ34967.1 - 2.8e-29 101.5 0.2 7.4e-29 100.2 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EEQ34967.1 - 6.8e-25 87.7 0.0 2.7e-24 85.8 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EEQ34967.1 - 9.5e-20 71.2 0.0 3.2e-19 69.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EEQ34967.1 - 6.6e-18 66.1 0.0 3.3e-16 60.6 0.0 3.4 4 0 0 4 4 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EEQ34967.1 - 1.2e-15 57.6 0.0 3.3e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EEQ34967.1 - 2.6e-12 46.9 0.0 8.6e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ34967.1 - 4.9e-12 46.4 0.0 1.8e-11 44.6 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ34967.1 - 2.4e-11 43.7 0.0 6.8e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ34967.1 - 9.4e-11 42.2 0.0 2.7e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EEQ34967.1 - 1.6e-08 34.4 0.0 7.3e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EEQ34967.1 - 5.7e-08 32.4 0.4 1.8e-05 24.3 0.1 3.4 3 0 0 3 3 3 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EEQ34967.1 - 1.1e-07 31.2 0.0 0.00027 20.0 0.0 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_N PF08240.12 EEQ34967.1 - 8.7e-05 22.4 0.2 0.00033 20.5 0.1 2.1 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EEQ34967.1 - 0.00022 21.5 0.0 0.00066 20.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EEQ34967.1 - 0.00033 20.1 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 EEQ34967.1 - 0.0012 18.5 0.3 0.003 17.1 0.0 1.8 2 0 0 2 2 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 EEQ34967.1 - 0.0048 16.3 0.0 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EEQ34967.1 - 0.033 13.6 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 EEQ34967.1 - 0.043 13.6 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 Lysine methyltransferase Polysacc_synt_2 PF02719.15 EEQ34967.1 - 0.056 12.6 0.0 0.94 8.5 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 EEQ34968.1 - 1.7e-93 312.8 0.3 2.6e-93 312.2 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EEQ34968.1 - 6.5e-44 148.5 2.0 9.4e-44 148.0 1.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EEQ34968.1 - 1.3e-05 24.9 2.7 3e-05 23.7 1.8 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EEQ34968.1 - 0.069 13.0 1.8 2.4 8.1 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.22 EEQ34969.1 - 1.5e-50 172.3 4.9 8.2e-50 169.9 4.9 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2401 PF10287.9 EEQ34970.1 - 1.4e-75 253.8 0.0 2e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EEQ34970.1 - 3.2e-23 81.9 0.0 8.9e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Atg14 PF10186.9 EEQ34973.1 - 1.1e-84 284.3 0.0 1.4e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 SLATT_1 PF18181.1 EEQ34974.1 - 0.018 14.9 1.5 0.024 14.6 0.8 1.5 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 LMBR1 PF04791.16 EEQ34975.1 - 9.3e-18 64.4 2.9 9.3e-18 64.4 2.9 2.3 1 1 0 2 2 2 2 LMBR1-like membrane protein DUF5367 PF17329.2 EEQ34975.1 - 0.0032 17.6 2.0 0.0032 17.6 2.0 4.5 7 1 1 8 8 8 1 Family of unknown function (DUF5367) DUF3611 PF12263.8 EEQ34975.1 - 0.075 12.9 0.1 0.075 12.9 0.1 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3611) DUF4470 PF14737.6 EEQ34977.1 - 1.9e-25 88.9 0.1 3.9e-25 87.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EEQ34977.1 - 5.3e-11 42.4 10.2 1.1e-10 41.3 10.2 1.6 1 0 0 1 1 1 1 MYND finger FlxA PF14282.6 EEQ34979.1 - 0.21 11.6 2.9 5 7.2 0.7 2.5 2 0 0 2 2 2 0 FlxA-like protein PIG-F PF06699.11 EEQ34980.1 - 2.8e-65 219.9 8.2 3.3e-65 219.6 8.2 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F TMEM65 PF10507.9 EEQ34980.1 - 0.034 14.1 0.0 10 6.1 0.0 2.7 2 0 0 2 2 2 0 Transmembrane protein 65 Na_Pi_cotrans PF02690.15 EEQ34980.1 - 3.7 7.6 5.7 2.2 8.4 0.0 2.8 3 0 0 3 3 3 0 Na+/Pi-cotransporter RDD PF06271.12 EEQ34980.1 - 3.9 7.7 8.7 0.14 12.3 0.5 2.3 2 1 1 3 3 3 0 RDD family Bacteriocin_IIc PF10439.9 EEQ34980.1 - 6.3 7.0 11.6 29 4.9 11.6 2.1 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Amidase PF01425.21 EEQ34981.1 - 6.4e-91 305.6 0.0 1.4e-90 304.5 0.0 1.4 1 1 0 1 1 1 1 Amidase Lipoprotein_7 PF01540.16 EEQ34983.1 - 0.031 13.6 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein ADH_N PF08240.12 EEQ34985.1 - 1.7e-26 92.2 0.7 3.4e-26 91.3 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ34985.1 - 6.5e-19 68.2 0.2 1.5e-18 67.0 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EEQ34985.1 - 0.0079 15.5 0.5 0.014 14.7 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EEQ34985.1 - 0.037 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EEQ34985.1 - 0.091 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-Tim10_DDP PF02953.15 EEQ34986.1 - 3.4e-16 58.6 4.7 4.8e-16 58.1 4.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SLBP_RNA_bind PF15247.6 EEQ34986.1 - 0.15 12.2 0.0 1.2 9.3 0.0 2.1 1 1 1 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Sigma70_r1_2 PF00140.20 EEQ34986.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Pkinase PF00069.25 EEQ34987.1 - 1.1e-26 93.8 0.0 4.5e-26 91.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ34987.1 - 6.1e-12 45.4 0.0 4e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ34987.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GRA6 PF05084.13 EEQ34988.1 - 0.0069 16.4 0.0 0.0069 16.4 0.0 1.1 1 0 0 1 1 1 1 Granule antigen protein (GRA6) CsgE PF10627.9 EEQ34989.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Curli assembly protein CsgE RhoGAP PF00620.27 EEQ34992.1 - 9.5e-39 132.7 0.0 1.6e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Amidase PF01425.21 EEQ34993.1 - 1.7e-74 251.4 2.6 1.1e-70 238.9 1.6 3.1 1 1 0 2 2 2 2 Amidase NAD_binding_5 PF07994.12 EEQ34995.1 - 1.2e-145 484.9 0.0 1.4e-145 484.7 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EEQ34995.1 - 5e-45 152.2 0.6 1.1e-44 151.1 0.6 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Ribonuclease_3 PF00636.26 EEQ34997.1 - 2.5e-07 31.3 0.0 1.3e-06 29.0 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EEQ34997.1 - 5e-06 26.7 0.0 6.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like SmpA_OmlA PF04355.13 EEQ34997.1 - 0.0038 17.0 0.1 3.5 7.5 0.0 2.5 2 1 0 2 2 2 2 SmpA / OmlA family Peptidase_S10 PF00450.22 EEQ34998.1 - 1.5e-74 251.9 0.2 2e-74 251.5 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase LIM PF00412.22 EEQ35000.1 - 2.2e-18 66.2 16.9 2.9e-11 43.4 2.7 3.0 3 0 0 3 3 3 2 LIM domain Glyco_hydro_3 PF00933.21 EEQ35001.1 - 8.6e-56 189.6 0.0 1e-55 189.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain ORMDL PF04061.14 EEQ35002.1 - 5.8 6.7 9.8 0.66 9.8 1.9 2.9 3 1 0 3 3 3 0 ORMDL family COesterase PF00135.28 EEQ35003.1 - 2.7e-80 270.7 0.1 1.9e-70 238.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EEQ35003.1 - 4.7e-09 36.4 0.0 7.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_2 PF00891.18 EEQ35004.1 - 3.1e-24 85.5 0.0 4.6e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EEQ35004.1 - 0.13 12.1 0.0 1.5 8.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF5137 PF17220.3 EEQ35005.1 - 0.11 13.4 0.3 0.21 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF5137) Peptidase_M4_C PF02868.15 EEQ35005.1 - 0.62 9.9 2.4 1.3 8.8 0.8 2.2 2 1 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Pkinase PF00069.25 EEQ35006.1 - 2.2e-10 40.3 0.0 4.1e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35006.1 - 2.7e-07 30.1 0.0 5.7e-07 29.1 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EEQ35006.1 - 1.7e-05 24.8 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ35006.1 - 0.0055 16.0 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EEQ35006.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Lbh PF15317.6 EEQ35009.1 - 0.062 14.2 0.4 0.18 12.7 0.6 1.7 2 1 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein AAA_11 PF13086.6 EEQ35010.1 - 2.3e-64 217.7 0.3 4.6e-64 216.7 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EEQ35010.1 - 2.5e-55 187.2 0.0 6e-55 186.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEQ35010.1 - 3.6e-13 49.7 0.0 6e-12 45.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ35010.1 - 4.8e-11 43.2 0.0 2.1e-10 41.1 0.0 2.2 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 EEQ35010.1 - 1.7e-08 34.5 0.2 0.083 12.6 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EEQ35010.1 - 1.8e-06 27.5 0.3 1e-05 25.0 0.3 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EEQ35010.1 - 4e-06 27.0 0.0 1.3e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EEQ35010.1 - 7.4e-06 25.7 0.1 0.00042 19.9 0.0 2.4 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EEQ35010.1 - 3.1e-05 24.3 0.1 0.00034 20.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EEQ35010.1 - 0.00018 21.4 0.0 0.022 14.6 0.0 3.1 2 1 0 2 2 2 1 Helicase AAA_16 PF13191.6 EEQ35010.1 - 0.00049 20.5 0.2 0.0018 18.7 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EEQ35010.1 - 0.0011 18.1 0.0 0.0027 16.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EEQ35010.1 - 0.003 17.5 0.0 0.0094 15.9 0.0 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain PhoH PF02562.16 EEQ35010.1 - 0.0038 16.7 0.0 0.4 10.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 EEQ35010.1 - 0.011 16.1 0.0 0.058 13.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EEQ35010.1 - 0.013 15.3 0.0 0.041 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EEQ35010.1 - 0.013 15.3 0.0 0.053 13.3 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 EEQ35010.1 - 0.017 14.1 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD_C_2 PF13538.6 EEQ35010.1 - 0.027 14.3 0.0 0.35 10.7 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 EEQ35010.1 - 0.029 14.3 0.2 0.14 12.2 0.0 2.4 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) PIF1 PF05970.14 EEQ35010.1 - 0.032 13.4 0.0 1.6 7.8 0.0 2.5 2 0 0 2 2 2 0 PIF1-like helicase UvrD_C PF13361.6 EEQ35010.1 - 0.034 13.5 0.0 5 6.4 0.0 2.6 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain TK PF00265.18 EEQ35010.1 - 0.066 13.1 0.0 0.9 9.4 0.0 2.3 2 0 0 2 2 2 0 Thymidine kinase AAA_33 PF13671.6 EEQ35010.1 - 0.069 13.3 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 EEQ35010.1 - 0.088 12.7 0.1 0.83 9.5 0.0 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EEQ35010.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SRP54 PF00448.22 EEQ35010.1 - 0.14 11.8 0.0 7.9 6.0 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PCB_OB PF17092.5 EEQ35010.1 - 0.19 12.5 0.7 19 6.1 0.1 3.2 2 1 1 3 3 3 0 Penicillin-binding protein OB-like domain HhH-GPD PF00730.25 EEQ35011.1 - 2.4e-20 73.0 0.0 4.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EEQ35011.1 - 7.7e-06 25.5 0.0 2.6e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif UQ_con PF00179.26 EEQ35012.1 - 2.4e-39 134.2 0.0 2.7e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 EEQ35012.1 - 0.0034 17.0 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 EEQ35012.1 - 0.039 14.2 0.5 0.052 13.8 0.5 1.5 1 1 0 1 1 1 0 RWD domain BRE PF06113.12 EEQ35012.1 - 0.058 12.2 0.1 0.089 11.6 0.1 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Methyltransf_23 PF13489.6 EEQ35013.1 - 1.3e-20 73.9 0.0 1.9e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ35013.1 - 1.5e-10 41.7 0.0 4.2e-10 40.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ35013.1 - 1.7e-07 31.9 0.0 9.7e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ35013.1 - 2.6e-07 30.6 0.0 7.2e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ35013.1 - 5.9e-06 26.8 0.0 1.3e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EEQ35013.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EEQ35013.1 - 0.0047 16.5 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EEQ35013.1 - 0.0069 16.5 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MmlI PF09448.10 EEQ35013.1 - 0.045 14.2 0.1 1.9 9.0 0.0 2.3 2 0 0 2 2 2 0 Methylmuconolactone methyl-isomerase CMAS PF02353.20 EEQ35013.1 - 0.083 12.2 0.0 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EEQ35013.1 - 0.088 12.5 0.0 2.9 7.6 0.0 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 EEQ35013.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 EEQ35013.1 - 0.15 11.3 0.0 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family p450 PF00067.22 EEQ35016.1 - 3.6e-50 171.1 0.0 3.7e-35 121.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HNH_2 PF13391.6 EEQ35017.1 - 3e-11 43.3 0.0 7.3e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 HNH endonuclease AMP-binding_C PF13193.6 EEQ35017.1 - 2.4e-06 28.4 0.0 1e-05 26.4 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Cu_amine_oxid PF01179.20 EEQ35018.1 - 2.4e-154 514.2 2.1 3.9e-152 506.9 2.1 2.0 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EEQ35018.1 - 0.00022 21.6 0.0 0.00052 20.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Tim17 PF02466.19 EEQ35019.1 - 5.2e-10 39.7 1.0 8.2e-10 39.0 1.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 EEQ35019.1 - 0.47 10.6 3.6 3.5 7.8 0.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5518) Cpn60_TCP1 PF00118.24 EEQ35020.1 - 0.0065 15.1 0.0 0.0069 15.1 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PALP PF00291.25 EEQ35021.1 - 1.3e-31 110.1 0.0 4.2e-30 105.2 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 EEQ35021.1 - 1.6e-08 35.0 0.0 1.5e-07 31.9 0.0 2.6 1 1 0 1 1 1 1 Rhodanese-like domain MFS_1 PF07690.16 EEQ35022.1 - 6.4e-39 133.9 41.7 3.2e-36 125.0 40.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EEQ35022.1 - 1.4e-16 60.1 22.4 1.8e-16 59.7 22.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPSF_A PF03178.15 EEQ35023.1 - 1.9e-99 333.0 0.0 6.1e-99 331.4 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 EEQ35023.1 - 2.9e-18 65.8 0.0 5.2e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term AAA PF00004.29 EEQ35025.1 - 2.2e-32 112.2 0.0 3.5e-27 95.4 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ35025.1 - 1e-09 38.0 0.5 2.7e-09 36.7 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain IstB_IS21 PF01695.17 EEQ35025.1 - 1.2e-06 28.4 0.0 2.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 EEQ35025.1 - 5.7e-06 26.8 0.1 6.1e-05 23.5 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EEQ35025.1 - 9e-06 25.9 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.25 EEQ35025.1 - 0.00013 22.0 0.0 0.00039 20.4 0.0 1.8 1 0 0 1 1 1 1 Bromodomain RNA_helicase PF00910.22 EEQ35025.1 - 0.0026 18.1 0.0 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 EEQ35025.1 - 0.0049 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ35025.1 - 0.0077 16.5 0.4 0.085 13.1 0.2 2.9 3 1 0 3 3 2 1 AAA domain AAA_25 PF13481.6 EEQ35025.1 - 0.011 15.3 0.0 0.036 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EEQ35025.1 - 0.013 15.7 0.0 0.049 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EEQ35025.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 EEQ35025.1 - 0.018 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEQ35025.1 - 0.02 15.4 0.0 0.074 13.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 EEQ35025.1 - 0.028 14.5 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 EEQ35025.1 - 0.033 13.6 0.0 0.083 12.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EEQ35025.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EEQ35025.1 - 0.078 12.7 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 EEQ35025.1 - 0.095 12.6 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EEQ35025.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EEQ35025.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 EEQ35025.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EEQ35025.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 EEQ35025.1 - 0.21 11.1 0.0 0.59 9.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EEQ35025.1 - 0.23 12.0 0.0 0.23 12.0 0.0 2.5 3 0 0 3 3 1 0 AAA domain AAA_11 PF13086.6 EEQ35025.1 - 0.74 9.6 0.0 0.74 9.6 0.0 3.4 3 1 0 3 3 2 0 AAA domain Sec66 PF09802.9 EEQ35026.1 - 2.7e-78 261.7 0.7 3.2e-78 261.4 0.7 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 EEQ35026.1 - 0.0002 21.3 0.2 0.00036 20.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3848) DUF1539 PF07560.11 EEQ35026.1 - 0.009 16.1 0.0 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1539) DUF2465 PF10239.9 EEQ35026.1 - 0.025 13.8 0.2 0.034 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) ORC3_N PF07034.11 EEQ35027.1 - 4.2e-33 114.8 0.0 6.1e-19 68.3 0.0 2.6 3 0 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EEQ35027.1 - 7.9e-24 84.3 0.1 9.5e-14 51.7 0.0 2.4 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal Symplekin_C PF12295.8 EEQ35027.1 - 0.0033 17.5 0.4 0.073 13.2 0.0 2.9 3 1 0 3 3 3 1 Symplekin tight junction protein C terminal FliG_C PF01706.16 EEQ35027.1 - 0.089 13.0 0.1 0.52 10.5 0.0 2.4 2 0 0 2 2 2 0 FliG C-terminal domain PPR_2 PF13041.6 EEQ35028.1 - 3e-08 33.7 3.5 1.4 9.2 0.0 6.0 7 0 0 7 7 7 4 PPR repeat family PPR PF01535.20 EEQ35028.1 - 0.0012 19.0 1.6 1.5 9.3 0.1 4.6 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 EEQ35028.1 - 0.007 16.4 0.2 6.5 6.9 0.1 2.9 3 0 0 3 3 3 2 Pentatricopeptide repeat domain DUF2716 PF10898.8 EEQ35028.1 - 0.12 12.7 0.3 1 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) HEAT_2 PF13646.6 EEQ35029.1 - 0.0025 18.2 0.1 0.0052 17.1 0.1 1.6 1 0 0 1 1 1 1 HEAT repeats PaaA_PaaC PF05138.12 EEQ35029.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein Nop14 PF04147.12 EEQ35030.1 - 2.4e-292 972.4 16.3 3.1e-292 972.0 16.3 1.1 1 0 0 1 1 1 1 Nop14-like family COesterase PF00135.28 EEQ35031.1 - 1.4e-86 291.5 0.0 1.8e-86 291.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EEQ35031.1 - 1.2e-06 28.6 0.0 3.5e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ35031.1 - 3.3e-05 23.5 0.0 5.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EEQ35031.1 - 0.00052 20.7 0.1 0.00089 19.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EEQ35031.1 - 0.0075 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF1749 PF08538.10 EEQ35031.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) APH PF01636.23 EEQ35034.1 - 7.1e-14 52.3 0.0 9.2e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ35034.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_M6 PF05547.11 EEQ35035.1 - 8.4e-06 24.4 1.6 0.00041 18.8 0.4 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 RabGAP-TBC PF00566.18 EEQ35036.1 - 5.1e-41 140.7 0.0 3.3e-39 134.8 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Pkinase PF00069.25 EEQ35037.1 - 4.8e-21 75.3 0.0 7.2e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EEQ35037.1 - 2.7e-09 37.5 6.5 2.1e-05 25.2 0.0 5.5 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.22 EEQ35037.1 - 4.8e-07 29.5 9.4 0.3 11.5 0.2 6.3 7 0 0 7 7 7 2 HEAT repeat Pkinase_Tyr PF07714.17 EEQ35037.1 - 1.2e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EEQ35037.1 - 0.00023 21.5 1.2 13 6.3 0.0 4.4 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EEQ35037.1 - 0.006 17.1 0.1 0.37 11.4 0.1 3.5 3 0 0 3 3 3 1 HEAT-like repeat Tti2 PF10521.9 EEQ35037.1 - 0.0065 16.1 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 Tti2 family zf-C2H2 PF00096.26 EEQ35039.1 - 9.9e-10 38.3 19.8 0.00078 19.8 3.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ35039.1 - 1.5e-08 34.8 16.1 0.0056 17.4 1.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEQ35039.1 - 0.015 15.7 17.3 2.7 8.6 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 EEQ35039.1 - 0.038 13.7 14.4 0.51 10.1 0.5 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 EEQ35039.1 - 0.085 13.0 8.3 1.5 9.0 1.4 2.8 2 0 0 2 2 2 0 Zinc ribbon domain DUF2852 PF11014.8 EEQ35039.1 - 0.098 12.8 1.3 0.65 10.2 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) zf-C2H2_8 PF15909.5 EEQ35039.1 - 0.12 12.7 6.9 0.55 10.6 6.4 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon CpXC PF14353.6 EEQ35039.1 - 0.54 10.3 6.4 3.4 7.7 0.5 2.3 1 1 1 2 2 2 0 CpXC protein zf-met PF12874.7 EEQ35039.1 - 0.67 10.4 4.8 12 6.5 2.8 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ35039.1 - 2.1 8.5 13.7 0.98 9.5 1.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger FdhD-NarQ PF02634.15 EEQ35039.1 - 2.1 7.9 5.8 7 6.3 0.5 2.1 1 1 1 2 2 2 0 FdhD/NarQ family zinc-ribbons_6 PF07191.12 EEQ35039.1 - 3.2 7.8 8.4 0.91 9.5 0.9 2.5 2 0 0 2 2 2 0 zinc-ribbons NUDIX PF00293.28 EEQ35040.1 - 6.5e-25 87.7 0.0 9.2e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF202 PF02656.15 EEQ35041.1 - 6.4e-16 58.6 5.4 9.2e-16 58.0 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tetraspanin PF00335.20 EEQ35041.1 - 0.43 10.2 3.8 1.3 8.7 2.9 1.8 2 0 0 2 2 2 0 Tetraspanin family MatE PF01554.18 EEQ35042.1 - 4e-55 185.9 32.9 3e-33 114.7 11.3 2.3 2 0 0 2 2 2 2 MatE DnaJ PF00226.31 EEQ35043.1 - 1.3e-14 54.0 1.3 5.9e-14 52.0 0.4 2.4 2 0 0 2 2 2 1 DnaJ domain Afi1 PF07792.12 EEQ35043.1 - 0.58 10.6 2.7 1.2 9.6 2.7 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DEAD PF00270.29 EEQ35044.1 - 8.7e-47 159.1 0.0 1.8e-46 158.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ35044.1 - 1.5e-23 83.2 0.0 9.8e-23 80.6 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEQ35044.1 - 2.8e-21 75.5 0.0 7.2e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EEQ35044.1 - 6.2e-08 32.8 0.4 1.7e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EEQ35044.1 - 0.011 15.9 0.1 0.06 13.5 0.0 2.2 2 0 0 2 2 2 0 Helicase C-terminal domain AA_permease PF00324.21 EEQ35045.1 - 3.6e-126 421.6 36.4 4.1e-126 421.4 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ35045.1 - 3.8e-38 131.4 42.8 4.7e-38 131.1 42.8 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 EEQ35045.1 - 0.032 14.9 1.3 0.032 14.9 1.3 3.8 4 1 1 5 5 5 0 PrgI family protein Zn_clus PF00172.18 EEQ35046.1 - 0.00025 21.1 10.5 0.00038 20.5 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ALMS_repeat PF18727.1 EEQ35047.1 - 0.034 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Alstrom syndrome repeat DEAD PF00270.29 EEQ35048.1 - 7.2e-36 123.6 0.0 1.9e-35 122.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ35048.1 - 3e-24 85.5 0.1 1.5e-23 83.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EEQ35048.1 - 3.9e-19 68.7 1.7 3.9e-19 68.7 1.7 2.4 2 0 0 2 2 2 1 DBP10CT (NUC160) domain RPA_C PF08784.11 EEQ35049.1 - 6.7e-14 52.4 0.0 1.7e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EEQ35049.1 - 0.0001 22.2 0.0 0.00068 19.6 0.0 2.1 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PAPS_reduct PF01507.19 EEQ35050.1 - 9.9e-28 97.3 0.0 1e-25 90.8 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.22 EEQ35051.1 - 6.7e-20 70.7 1.2 2.8e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEQ35051.1 - 0.04 13.9 0.1 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif FAD_binding_1 PF00667.20 EEQ35052.1 - 2.2e-68 230.2 0.0 3.1e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EEQ35052.1 - 2.6e-35 121.7 0.6 4.8e-35 120.9 0.6 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EEQ35052.1 - 3.7e-19 69.4 0.0 3.6e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EEQ35052.1 - 0.035 14.3 0.1 0.62 10.3 0.0 2.5 2 0 0 2 2 2 0 Flavodoxin domain MOR2-PAG1_N PF14222.6 EEQ35053.1 - 3.3e-212 706.3 0.0 5.3e-212 705.6 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EEQ35053.1 - 3.9e-69 233.3 4.0 1.9e-52 178.6 0.2 3.2 2 1 1 3 3 3 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EEQ35053.1 - 1e-40 139.3 10.2 1.1e-17 63.1 0.0 4.1 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT_EZ PF13513.6 EEQ35053.1 - 0.47 11.0 1.5 36 5.0 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat Git3 PF11710.8 EEQ35054.1 - 7.8e-22 78.0 16.3 2.1e-21 76.7 16.3 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EEQ35054.1 - 9.4e-11 41.6 0.5 5.8e-10 39.1 0.5 2.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term DENN PF02141.21 EEQ35056.1 - 1e-37 129.9 0.1 1.8e-37 129.1 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EEQ35056.1 - 8.7e-06 26.4 0.1 3.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 EEQ35056.1 - 0.065 13.8 6.8 0.073 13.6 4.6 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A ATG16 PF08614.11 EEQ35056.1 - 0.37 11.0 19.3 0.04 14.1 6.6 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 EEQ35056.1 - 1.5 9.1 16.4 0.58 10.4 4.2 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cnn_1N PF07989.11 EEQ35056.1 - 2.1 8.6 12.8 0.22 11.7 2.9 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 adh_short_C2 PF13561.6 EEQ35059.1 - 8.6e-54 182.6 1.2 1e-53 182.3 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ35059.1 - 4.9e-47 159.9 1.0 6.1e-47 159.6 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ35059.1 - 2.5e-10 40.6 0.7 5.6e-10 39.4 0.7 1.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EEQ35059.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sulfotransfer_3 PF13469.6 EEQ35060.1 - 0.008 16.6 0.2 0.079 13.3 0.2 2.3 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EEQ35060.1 - 0.021 14.3 0.0 0.29 10.6 0.0 2.5 1 1 0 1 1 1 0 Sulfotransferase domain DUF664 PF04978.12 EEQ35060.1 - 0.2 12.0 2.5 3.6 8.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF664) Sulfotransfer_3 PF13469.6 EEQ35061.1 - 0.035 14.5 0.0 7.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Sulfotransferase family Fez1 PF06818.15 EEQ35062.1 - 0.0031 18.0 0.9 0.0031 18.0 0.9 2.4 3 0 0 3 3 3 1 Fez1 Spc7 PF08317.11 EEQ35062.1 - 0.026 13.4 1.8 0.043 12.7 1.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 EEQ35062.1 - 0.052 12.6 3.6 0.12 11.4 3.6 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAP1_N PF04849.13 EEQ35062.1 - 0.089 12.0 6.2 0.18 11.0 6.2 1.5 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 EEQ35062.1 - 2.7 8.0 5.1 4 7.5 0.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LPP PF04728.13 EEQ35062.1 - 6.5 7.2 5.4 39 4.7 0.4 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Peptidase_C48 PF02902.19 EEQ35065.1 - 3.9e-25 89.0 0.0 5.7e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PAP2 PF01569.21 EEQ35066.1 - 4.4e-16 58.9 2.7 4.4e-16 58.9 2.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EEQ35066.1 - 0.0021 17.8 6.5 0.006 16.3 6.5 1.8 1 1 0 1 1 1 1 PAP2 superfamily Ras PF00071.22 EEQ35067.1 - 3.3e-47 160.1 0.0 4.2e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ35067.1 - 6.1e-20 71.6 0.0 9.7e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ35067.1 - 0.00018 21.0 0.0 0.0003 20.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EEQ35067.1 - 0.025 14.0 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EEQ35067.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DASH_Dad1 PF08649.10 EEQ35068.1 - 1.1e-22 80.0 2.4 1.4e-22 79.6 2.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EEQ35068.1 - 0.005 16.8 0.1 0.0073 16.3 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad4 GCP_C_terminal PF04130.13 EEQ35070.1 - 0.11 12.0 0.7 0.12 11.8 0.7 1.0 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal SR-25 PF10500.9 EEQ35070.1 - 0.17 11.5 11.0 0.19 11.3 11.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 EEQ35070.1 - 0.24 9.8 6.1 0.27 9.6 6.1 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) IMUP PF15761.5 EEQ35070.1 - 0.66 10.7 7.9 0.76 10.5 7.9 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein LSM PF01423.22 EEQ35071.1 - 2.2e-15 56.1 0.1 2.5e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF866 PF05907.13 EEQ35072.1 - 7e-58 194.9 0.5 7.7e-58 194.8 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) HalOD2 PF18547.1 EEQ35072.1 - 0.19 11.7 4.3 2 8.4 4.3 2.2 1 1 1 2 2 2 0 Halobacterial output domain 2 FAD_binding_3 PF01494.19 EEQ35073.1 - 1.4e-69 235.0 0.0 1.7e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EEQ35073.1 - 1.2e-36 126.2 0.0 2.2e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 EEQ35073.1 - 0.0035 17.0 0.1 0.043 13.4 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ35073.1 - 0.008 15.4 0.0 0.46 9.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEQ35073.1 - 0.2 10.3 0.0 0.41 9.3 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein APH PF01636.23 EEQ35074.1 - 5.4e-15 56.0 0.0 6.5e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ35074.1 - 1.5e-09 37.8 0.0 3.6e-09 36.5 0.0 1.6 1 1 1 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EEQ35074.1 - 0.00041 19.6 0.0 0.00062 19.0 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Pkinase PF00069.25 EEQ35074.1 - 0.011 15.1 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.20 EEQ35074.1 - 0.042 13.1 0.0 0.052 12.9 0.0 1.3 1 1 0 1 1 1 0 Ecdysteroid kinase fn1 PF00039.18 EEQ35074.1 - 0.17 12.1 0.2 0.41 10.9 0.2 1.6 1 0 0 1 1 1 0 Fibronectin type I domain DDHD PF02862.17 EEQ35076.1 - 2.3e-26 93.3 0.0 2e-24 87.0 0.0 2.5 1 1 0 1 1 1 1 DDHD domain CENP-U PF13097.6 EEQ35076.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Abhydrolase_6 PF12697.7 EEQ35076.1 - 0.13 12.9 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family MoCF_biosynth PF00994.24 EEQ35077.1 - 3e-47 159.9 0.1 1.1e-22 80.2 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EEQ35077.1 - 1.7e-38 131.9 2.1 2.8e-38 131.1 2.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EEQ35077.1 - 9.9e-18 64.1 0.1 2.2e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 EEQ35077.1 - 3 7.2 4.9 4.4 6.6 4.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ATP-synt_C PF00137.21 EEQ35078.1 - 4e-23 81.5 35.5 1.8e-16 60.2 10.8 2.6 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 EEQ35078.1 - 0.39 10.0 4.5 0.12 11.7 0.5 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Gram_pos_anchor PF00746.21 EEQ35078.1 - 6.5 6.8 5.4 6.7 6.8 0.5 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Ras PF00071.22 EEQ35079.1 - 7.9e-60 201.1 0.5 1e-59 200.8 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ35079.1 - 1.1e-36 125.7 0.2 1.7e-36 125.1 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ35079.1 - 4.9e-18 65.2 0.4 5.9e-18 64.9 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ35079.1 - 4.7e-06 26.3 0.1 2.9e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEQ35079.1 - 1.4e-05 25.2 0.1 3.6e-05 23.8 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EEQ35079.1 - 1.4e-05 24.6 0.1 1.9e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EEQ35079.1 - 2.4e-05 24.3 0.2 0.026 14.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EEQ35079.1 - 5.7e-05 22.6 0.3 7e-05 22.3 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 EEQ35079.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EEQ35079.1 - 0.084 12.9 0.4 9 6.3 0.0 2.7 2 1 1 3 3 3 0 Dynamin family TetR_C_16 PF17920.1 EEQ35079.1 - 0.21 11.9 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Kei1 PF08552.11 EEQ35080.1 - 1.9e-29 102.9 0.9 5.9e-29 101.3 0.9 1.7 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NIR_SIR PF01077.22 EEQ35081.1 - 9.7e-55 184.4 0.1 8e-47 158.7 0.0 2.8 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EEQ35081.1 - 6.1e-29 99.7 0.0 5.1e-14 51.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EEQ35081.1 - 5.7e-28 97.9 0.0 1.3e-27 96.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EEQ35081.1 - 2.9e-06 27.2 0.4 1.2e-05 25.2 0.1 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Sin_N PF04801.13 EEQ35082.1 - 1.4e-25 90.4 0.9 5.7e-25 88.4 0.9 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region RNA_pol PF00940.19 EEQ35083.1 - 4.4e-183 608.8 0.0 6.4e-183 608.3 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EEQ35083.1 - 2.3e-90 303.4 0.9 3.3e-90 302.9 0.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal YaiA PF16362.5 EEQ35083.1 - 0.13 12.3 1.0 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 YaiA protein Med4 PF10018.9 EEQ35083.1 - 0.3 10.7 2.1 0.27 10.9 0.1 1.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 T2SSI PF02501.17 EEQ35085.1 - 0.046 13.9 3.0 0.078 13.2 3.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I MAGE_N PF12440.8 EEQ35085.1 - 0.22 12.2 5.1 0.43 11.3 5.1 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Radical_SAM PF04055.21 EEQ35086.1 - 3.9e-11 43.6 0.0 5.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EEQ35086.1 - 3.7e-05 24.0 0.0 6.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EEQ35086.1 - 0.05 13.7 0.5 0.11 12.6 0.4 1.7 1 1 0 1 1 1 0 4Fe-4S single cluster domain Frankia_peptide PF14407.6 EEQ35086.1 - 0.19 11.8 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Pkinase PF00069.25 EEQ35087.1 - 1.9e-09 37.3 0.0 2.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EEQ35087.1 - 0.00027 20.9 0.0 0.00049 20.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ35087.1 - 0.00034 20.0 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FGF-BP1 PF06473.12 EEQ35088.1 - 0.074 12.9 6.3 0.13 12.1 6.3 1.5 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Pkinase PF00069.25 EEQ35089.1 - 2.2e-51 174.8 0.0 3.1e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35089.1 - 2.5e-30 105.6 0.0 3.8e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ35089.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FHA PF00498.26 EEQ35089.1 - 0.0066 16.8 0.0 0.022 15.1 0.0 1.9 2 0 0 2 2 2 1 FHA domain Kdo PF06293.14 EEQ35089.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEQ35089.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EEQ35090.1 - 8.9e-05 22.0 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EEQ35091.1 - 1.3e-16 61.3 0.0 4.2e-16 59.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ35091.1 - 0.0021 17.7 0.1 0.0046 16.6 0.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EEQ35091.1 - 0.16 11.1 0.0 0.5 9.5 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase SQHop_cyclase_N PF13249.6 EEQ35091.1 - 0.16 11.0 0.1 0.29 10.2 0.1 1.3 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain HTH_46 PF15977.5 EEQ35091.1 - 0.17 11.9 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding VATC PF18716.1 EEQ35091.1 - 1.1 9.2 3.7 0.25 11.2 0.2 1.7 2 0 0 2 2 2 0 Vms1-associating treble clef domain DUF438 PF04282.13 EEQ35093.1 - 0.089 12.8 1.2 0.58 10.1 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF438) Pkinase PF00069.25 EEQ35096.1 - 8.9e-15 54.8 0.0 1e-13 51.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35096.1 - 1.2e-13 50.9 0.0 7.4e-12 45.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EEQ35098.1 - 1.2e-12 47.8 0.0 1.5e-11 44.2 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35098.1 - 9.2e-07 28.4 0.0 8.3e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Profilin PF00235.19 EEQ35099.1 - 5.1e-23 81.7 0.0 6.4e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Profilin DUF2585 PF10755.9 EEQ35099.1 - 0.085 12.6 0.2 0.16 11.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2585) DUF92 PF01940.16 EEQ35100.1 - 2.1e-82 276.1 3.4 2.5e-82 275.9 3.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 K_oxygenase PF13434.6 EEQ35101.1 - 2.5e-09 36.8 0.1 0.00044 19.5 0.1 3.7 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EEQ35101.1 - 2.8e-07 29.4 0.0 4.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EEQ35101.1 - 1.7e-06 27.5 0.0 0.00036 19.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ35101.1 - 4.6e-06 26.8 0.0 2.1e-05 24.7 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EEQ35101.1 - 2.9e-05 23.5 0.0 0.0014 18.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Clathrin-link PF09268.10 EEQ35101.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Methyltransf_33 PF10017.9 EEQ35104.1 - 9.1e-88 294.4 0.0 1.2e-87 294.0 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EEQ35104.1 - 4.2e-21 75.7 2.1 1.9e-20 73.6 2.1 1.9 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EEQ35104.1 - 1.1e-05 26.0 0.3 9.1e-05 23.0 0.2 2.5 2 0 0 2 2 2 1 DinB superfamily DUF1069 PF06370.11 EEQ35104.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) SesA PF17107.5 EEQ35105.1 - 0.047 13.9 0.4 0.16 12.2 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Aldedh PF00171.22 EEQ35106.1 - 4.3e-130 434.3 0.0 4.8e-130 434.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EEQ35106.1 - 0.00012 21.3 0.0 0.0006 19.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) MFS_1 PF07690.16 EEQ35107.1 - 1.3e-30 106.6 46.4 1.3e-30 106.6 46.4 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ35107.1 - 1.7e-09 37.1 4.9 1.7e-09 37.1 4.9 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter DUF872 PF05915.12 EEQ35107.1 - 7.1 6.8 7.2 1.6 8.9 0.1 3.3 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Fungal_trans PF04082.18 EEQ35108.1 - 5.1e-09 35.6 0.2 8.5e-09 34.8 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ35108.1 - 1.6e-06 28.1 6.5 3.3e-06 27.1 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EEQ35108.1 - 0.0022 18.7 23.4 0.022 15.6 2.1 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EEQ35108.1 - 0.015 15.7 20.8 0.036 14.5 5.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 EEQ35108.1 - 0.25 11.7 12.5 0.12 12.7 9.5 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EEQ35108.1 - 4.6 7.8 22.8 0.31 11.5 2.0 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Lipase_GDSL_2 PF13472.6 EEQ35110.1 - 7.9e-12 45.9 0.4 8.6e-11 42.5 0.4 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EEQ35110.1 - 1.7e-05 24.9 0.1 5.4e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EEQ35110.1 - 0.14 12.2 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family TFIIA_gamma_C PF02751.14 EEQ35111.1 - 1.4e-24 85.9 1.4 1.4e-24 85.9 1.4 1.6 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EEQ35111.1 - 1.7e-24 85.5 0.1 2.4e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Hexokinase_1 PF00349.21 EEQ35114.1 - 8.9e-62 208.5 0.0 1.2e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EEQ35114.1 - 6.1e-43 147.0 0.0 2e-42 145.3 0.0 1.8 1 1 0 1 1 1 1 Hexokinase Phosphoprotein PF00922.17 EEQ35114.1 - 0.061 12.9 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein GILT PF03227.16 EEQ35115.1 - 8.6e-15 54.9 1.0 8e-14 51.8 1.0 2.3 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) MFS_1 PF07690.16 EEQ35117.1 - 2.2e-21 76.2 30.3 2.1e-17 63.1 13.3 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily GCP_N_terminal PF17681.1 EEQ35118.1 - 2.1e-30 106.4 0.0 8e-30 104.5 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EEQ35118.1 - 4.3e-25 88.8 0.0 7.1e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF4290 PF14123.6 EEQ35118.1 - 0.027 14.0 0.1 0.059 12.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4290) CBM_19 PF03427.13 EEQ35119.1 - 0.007 16.3 1.3 0.007 16.3 1.3 2.0 3 0 0 3 3 3 1 Carbohydrate binding domain (family 19) ThiF PF00899.21 EEQ35120.1 - 1e-114 381.9 0.0 3.7e-75 252.4 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EEQ35120.1 - 3.4e-95 318.8 1.1 9.9e-95 317.2 0.6 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EEQ35120.1 - 3.3e-31 107.3 0.1 8e-31 106.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EEQ35120.1 - 3.9e-29 101.2 0.0 7.7e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EEQ35120.1 - 8.5e-25 86.7 1.6 8.5e-25 86.7 1.6 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 EEQ35120.1 - 0.00082 19.8 0.0 0.0068 16.8 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding GST_N_2 PF13409.6 EEQ35122.1 - 7.4e-23 80.6 0.0 2.2e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ35122.1 - 7.1e-10 38.8 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EEQ35122.1 - 2.8e-06 27.6 0.1 0.00013 22.3 0.1 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEQ35122.1 - 0.0028 17.9 0.0 0.0097 16.1 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ35122.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.27 EEQ35123.1 - 4e-47 158.1 9.0 1.1e-22 79.8 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EEQ35123.1 - 1.1e-20 73.9 4.5 4.2e-11 43.1 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EEQ35123.1 - 5.4e-18 63.1 3.8 0.0002 20.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EEQ35123.1 - 8.8e-16 56.4 6.9 2.4e-05 23.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EEQ35123.1 - 9.8e-16 56.5 3.6 0.00018 20.9 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EEQ35123.1 - 8.4e-11 41.5 3.6 1.7e-05 24.5 0.2 3.6 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EEQ35123.1 - 1.2e-09 38.5 0.4 2.1e-05 24.8 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EEQ35123.1 - 0.0038 17.1 4.5 0.25 11.3 0.5 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EEQ35123.1 - 0.0078 16.0 0.2 4 7.4 0.0 2.5 2 0 0 2 2 2 2 EF hand DNA_PPF PF02916.15 EEQ35123.1 - 0.2 12.0 0.0 0.49 10.8 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase processivity factor Cyclin_N PF00134.23 EEQ35124.1 - 2.6e-11 43.3 0.1 4e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EEQ35124.1 - 0.053 13.9 0.1 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 Cyclin C-terminal domain DUF4452 PF14618.6 EEQ35125.1 - 8.6e-48 162.4 9.5 1.5e-47 161.6 9.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4452) Chorion_2 PF03964.15 EEQ35125.1 - 2.5 9.0 8.5 4 8.3 4.4 2.1 2 0 0 2 2 2 0 Chorion family 2 SUIM_assoc PF16619.5 EEQ35125.1 - 3.8 7.6 9.4 9.1 6.4 0.1 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HEPN_SAV_6107 PF18726.1 EEQ35126.1 - 0.0062 17.0 0.2 0.0085 16.6 0.2 1.3 1 0 0 1 1 1 1 SAV_6107-like HEPN F-box-like PF12937.7 EEQ35127.1 - 9.9e-06 25.4 1.4 2.4e-05 24.1 1.4 1.7 1 0 0 1 1 1 1 F-box-like DUF3433 PF11915.8 EEQ35128.1 - 3.3e-34 117.2 19.6 5.7e-21 74.8 5.6 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Pkinase PF00069.25 EEQ35129.1 - 4.8e-12 45.8 0.0 1.5e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35129.1 - 1.6e-11 44.0 0.0 3.1e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EEQ35129.1 - 0.00038 20.1 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EEQ35129.1 - 0.011 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ35129.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cwf_Cwc_15 PF04889.12 EEQ35130.1 - 7.7e-05 22.5 24.5 0.0001 22.2 24.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Mitofilin PF09731.9 EEQ35130.1 - 0.072 11.9 18.1 0.091 11.6 18.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Exonuc_VII_L PF02601.15 EEQ35130.1 - 0.13 11.9 8.5 0.14 11.7 8.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CNDH2_C PF16858.5 EEQ35130.1 - 0.41 10.5 14.6 0.51 10.2 14.6 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Prominin PF05478.11 EEQ35130.1 - 0.44 8.4 6.5 0.54 8.2 6.5 1.0 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 EEQ35130.1 - 0.86 9.7 13.8 1.1 9.3 13.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BUD22 PF09073.10 EEQ35130.1 - 0.86 8.9 20.2 0.98 8.7 20.2 1.1 1 0 0 1 1 1 0 BUD22 FapA PF03961.13 EEQ35130.1 - 1.1 7.8 7.2 1.3 7.5 7.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 EEQ35130.1 - 1.2 7.0 9.4 1.5 6.6 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.13 EEQ35130.1 - 1.4 8.8 18.1 1.8 8.5 18.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4746 PF15928.5 EEQ35130.1 - 2.5 7.5 9.2 3.1 7.1 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TMPIT PF07851.13 EEQ35130.1 - 3.6 6.7 8.6 4.3 6.5 8.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein PPP4R2 PF09184.11 EEQ35130.1 - 4.7 6.7 18.9 6 6.4 18.9 1.1 1 0 0 1 1 1 0 PPP4R2 Spore_III_AB PF09548.10 EEQ35130.1 - 5.8 7.0 10.4 8.3 6.5 10.4 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) LMBR1 PF04791.16 EEQ35130.1 - 7 5.4 8.7 8 5.2 8.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein KASH_CCD PF14662.6 EEQ35131.1 - 0.07 13.0 4.8 0.072 12.9 3.0 1.8 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH bZIP_2 PF07716.15 EEQ35131.1 - 3.5 7.8 7.2 7.6 6.7 1.9 3.1 2 1 1 3 3 3 0 Basic region leucine zipper PTR2 PF00854.21 EEQ35133.1 - 6.2e-86 288.7 3.0 1.2e-85 287.8 3.0 1.4 1 1 0 1 1 1 1 POT family APH PF01636.23 EEQ35134.1 - 0.0019 18.2 0.0 0.15 12.0 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Chordopox_A15 PF05846.12 EEQ35134.1 - 0.027 14.7 0.4 0.058 13.6 0.1 1.8 2 0 0 2 2 2 0 Chordopoxvirus A15 protein APH PF01636.23 EEQ35135.1 - 1.7e-07 31.4 0.1 8.4e-07 29.1 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family HIF-1 PF11413.8 EEQ35135.1 - 0.14 11.6 0.1 0.32 10.4 0.1 1.6 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 NST1 PF13945.6 EEQ35137.1 - 0.19 11.8 1.1 0.24 11.5 1.1 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator AAA_12 PF13087.6 EEQ35140.1 - 9.2e-39 133.1 0.0 1.8e-38 132.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEQ35140.1 - 6.4e-21 75.3 1.7 3.1e-20 73.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EEQ35140.1 - 6.6e-08 32.2 0.2 0.00078 18.8 0.1 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EEQ35140.1 - 1.2e-07 32.2 0.0 6.9e-07 29.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain zf-CCCH_4 PF18044.1 EEQ35140.1 - 7.1e-07 28.9 3.5 7.1e-07 28.9 3.5 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger AAA_30 PF13604.6 EEQ35140.1 - 1.7e-06 27.9 0.2 0.00021 21.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EEQ35140.1 - 0.0085 16.1 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 EEQ35140.1 - 0.083 12.3 1.2 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI zf_CCCH_4 PF18345.1 EEQ35140.1 - 1.5 9.0 12.2 0.071 13.2 4.1 3.0 2 0 0 2 2 2 0 Zinc finger domain APH PF01636.23 EEQ35141.1 - 8.2e-15 55.4 0.0 1.2e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ35141.1 - 6.7e-05 22.6 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ35141.1 - 0.00099 18.5 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain PIP49_C PF12260.8 EEQ35141.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Peptidase_S8 PF00082.22 EEQ35142.1 - 1.8e-23 83.2 14.9 3.1e-23 82.5 14.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ35142.1 - 1.3e-14 54.6 0.2 2.4e-14 53.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 SNARE PF05739.19 EEQ35144.1 - 7.1e-11 41.9 0.7 4.3e-10 39.4 0.2 2.1 2 0 0 2 2 2 1 SNARE domain DUF1676 PF07898.13 EEQ35144.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) TPR_MLP1_2 PF07926.12 EEQ35144.1 - 0.078 13.0 0.5 0.078 13.0 0.5 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.11 EEQ35144.1 - 0.13 12.1 0.3 51 3.6 0.1 3.1 2 2 1 3 3 3 0 Phage minor structural protein GP20 Fzo_mitofusin PF04799.13 EEQ35144.1 - 0.3 10.6 0.7 8.7 5.9 0.1 2.2 2 0 0 2 2 2 0 fzo-like conserved region zf-RING_2 PF13639.6 EEQ35145.1 - 0.00037 20.8 15.0 0.00037 20.8 15.0 3.1 3 1 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 EEQ35145.1 - 0.0015 18.4 13.9 0.0015 18.4 13.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-TRAF PF02176.18 EEQ35145.1 - 0.0017 19.0 0.8 0.0017 19.0 0.8 3.5 3 1 1 4 4 3 2 TRAF-type zinc finger zf-RING_UBOX PF13445.6 EEQ35145.1 - 0.0029 17.6 13.1 0.0029 17.6 13.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EEQ35145.1 - 0.005 17.0 14.8 0.018 15.2 14.8 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EEQ35145.1 - 0.0077 16.1 11.5 0.0077 16.1 11.5 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ35145.1 - 0.0088 15.9 14.8 0.0088 15.9 14.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) TSC22 PF01166.18 EEQ35145.1 - 0.077 13.3 2.3 5.2 7.5 0.3 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 EEQ35145.1 - 0.33 11.0 2.8 0.8 9.7 0.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.8 EEQ35145.1 - 0.33 11.1 4.2 4.3 7.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DivIC PF04977.15 EEQ35145.1 - 0.34 10.7 1.3 3.9 7.3 0.4 2.4 2 0 0 2 2 2 0 Septum formation initiator Prok-RING_4 PF14447.6 EEQ35145.1 - 1.8 8.5 13.8 5.7 6.9 12.4 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Het-C PF07217.11 EEQ35148.1 - 1.1e-278 925.4 0.0 1.4e-278 925.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C FlgN PF05130.12 EEQ35150.1 - 0.021 15.3 2.2 0.037 14.5 1.1 1.9 2 0 0 2 2 2 0 FlgN protein UPF0242 PF06785.11 EEQ35150.1 - 0.12 12.5 1.8 0.35 11.0 2.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4375 PF14300.6 EEQ35150.1 - 2.9 8.2 5.1 2.4 8.4 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Ank_2 PF12796.7 EEQ35151.1 - 1.9e-36 124.5 0.4 5.5e-13 49.3 0.0 8.8 7 2 2 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ35151.1 - 1.2e-32 111.8 2.8 1.9e-08 34.7 0.0 10.7 9 2 2 11 11 11 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ35151.1 - 1.3e-27 95.5 5.4 0.00041 20.6 0.0 9.7 10 0 0 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ35151.1 - 8.1e-25 84.2 7.0 0.0033 17.8 0.0 12.5 12 0 0 12 12 12 4 Ankyrin repeat Ank PF00023.30 EEQ35151.1 - 1.3e-22 79.2 7.0 0.0019 18.6 0.1 9.0 9 1 0 9 9 9 5 Ankyrin repeat IBN_N PF03810.19 EEQ35152.1 - 5.7e-10 39.0 0.9 1.3e-08 34.6 0.1 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Proteasom_PSMB PF10508.9 EEQ35152.1 - 0.00012 20.7 0.4 0.00093 17.8 0.0 2.4 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit Xpo1 PF08389.12 EEQ35152.1 - 0.00029 20.9 0.0 0.017 15.2 0.0 3.3 2 0 0 2 2 2 1 Exportin 1-like protein RIX1 PF08167.12 EEQ35152.1 - 0.00051 19.8 0.4 0.053 13.3 0.0 3.8 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis CAS_CSE1 PF03378.15 EEQ35152.1 - 0.00079 18.0 0.0 0.0021 16.6 0.0 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus UL21a PF17636.2 EEQ35152.1 - 0.16 12.0 0.1 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Viral Unique Long protein 21a HORMA PF02301.18 EEQ35153.1 - 1.1e-09 38.2 0.0 2.6e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 HORMA domain IBR PF01485.21 EEQ35154.1 - 1.1 9.5 20.9 0.9 9.8 0.3 3.8 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Cu-oxidase PF00394.22 EEQ35155.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase Acetyltransf_7 PF13508.7 EEQ35156.1 - 3.6e-05 24.1 0.0 6.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEQ35156.1 - 0.0002 21.4 0.0 0.00045 20.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ35156.1 - 0.0018 18.2 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ35156.1 - 0.0024 17.8 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EEQ35156.1 - 0.014 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Dcc1 PF09724.9 EEQ35157.1 - 2.7e-22 79.5 0.1 3.7e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Anp1 PF03452.14 EEQ35158.1 - 8.3e-112 372.9 2.7 3.8e-111 370.7 0.0 2.2 2 0 0 2 2 2 1 Anp1 Smg8_Smg9 PF10220.9 EEQ35158.1 - 1.1 7.4 13.4 1.9 6.7 12.9 1.5 2 0 0 2 2 2 0 Smg8_Smg9 tRNA_bind PF01588.20 EEQ35159.1 - 6.6e-19 67.8 0.0 3.3e-18 65.6 0.0 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 EEQ35159.1 - 0.00099 19.1 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EEQ35159.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PGP_phosphatase PF09419.10 EEQ35159.1 - 0.085 12.5 0.1 0.24 11.0 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Exonuc_VIII PF06630.11 EEQ35159.1 - 0.091 12.6 0.2 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII Asp PF00026.23 EEQ35160.1 - 9.9e-61 205.9 0.0 1.2e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEQ35160.1 - 2.8e-09 37.5 0.2 0.0025 18.1 0.0 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EEQ35160.1 - 4.6e-06 27.2 0.5 0.04 14.5 0.2 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EEQ35160.1 - 0.00021 21.8 0.1 0.21 12.1 0.1 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease APH PF01636.23 EEQ35161.1 - 5e-12 46.3 0.0 1.5e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.11 EEQ35161.1 - 0.00023 20.2 0.0 0.26 10.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 EEQ35161.1 - 0.0072 15.6 0.0 0.51 9.5 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase EcKinase PF02958.20 EEQ35161.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.23 EEQ35162.1 - 1.4e-15 57.9 0.0 2.6e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ35162.1 - 0.0017 18.0 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EEQ35162.1 - 0.053 12.7 0.1 0.79 8.9 0.0 2.5 3 0 0 3 3 3 0 Fructosamine kinase Pkinase PF00069.25 EEQ35162.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Snapin_Pallidin PF14712.6 EEQ35163.1 - 0.003 17.9 6.2 0.0033 17.8 6.2 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DivIC PF04977.15 EEQ35163.1 - 0.011 15.4 6.2 0.71 9.7 0.3 2.1 1 1 1 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 EEQ35163.1 - 0.021 15.1 3.6 0.035 14.4 2.6 1.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4558 PF15104.6 EEQ35163.1 - 0.025 14.6 1.7 0.025 14.6 1.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4558) VRP1 PF03538.14 EEQ35163.1 - 0.041 13.3 0.6 0.044 13.2 0.6 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein HTH_35 PF13693.6 EEQ35163.1 - 0.09 12.8 0.1 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding ABC_tran_CTD PF16326.5 EEQ35163.1 - 0.1 12.9 10.2 0.25 11.6 7.3 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Prefoldin_2 PF01920.20 EEQ35163.1 - 0.19 11.7 8.5 0.45 10.5 4.6 2.0 1 1 1 2 2 2 0 Prefoldin subunit Fmp27_WPPW PF10359.9 EEQ35163.1 - 0.22 10.3 4.6 0.23 10.2 4.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ParA PF10609.9 EEQ35164.1 - 9.9e-96 319.9 0.0 1.1e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EEQ35164.1 - 6e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EEQ35164.1 - 7.2e-06 25.4 0.7 0.00025 20.4 0.2 2.5 1 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EEQ35164.1 - 7.8e-06 25.9 0.0 2.7e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EEQ35164.1 - 0.0051 16.1 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ CLP1_P PF16575.5 EEQ35164.1 - 0.0067 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_26 PF13500.6 EEQ35164.1 - 0.0092 15.8 0.1 2.2 8.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EEQ35164.1 - 0.024 14.6 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EEQ35164.1 - 0.03 13.9 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEQ35164.1 - 0.14 12.5 0.1 0.32 11.4 0.1 1.6 1 1 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EEQ35164.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ35164.1 - 0.18 12.2 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 EEQ35164.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PEMT PF04191.13 EEQ35165.1 - 1.9e-60 201.8 9.6 9.2e-37 125.7 0.6 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 EEQ35165.1 - 0.016 15.0 0.1 0.061 13.1 0.1 1.9 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 EEQ35165.1 - 0.027 15.0 0.1 1 10.0 0.0 2.4 2 0 0 2 2 2 0 SKICH domain RNase_PH PF01138.21 EEQ35166.1 - 2.5e-26 92.7 0.0 6.6e-26 91.4 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Choline_kinase PF01633.20 EEQ35169.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ProRS-C_1 PF09180.11 EEQ35170.1 - 8.4e-23 80.4 3.5 1.7e-22 79.4 3.5 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EEQ35170.1 - 1.9e-18 67.0 0.0 3.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EEQ35170.1 - 1.3e-12 47.7 0.0 2.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain PDH PF02153.17 EEQ35170.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Cpn60_TCP1 PF00118.24 EEQ35171.1 - 3e-150 501.1 15.6 3.4e-150 500.9 15.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 EEQ35172.1 - 3.4e-12 46.7 8.7 0.00093 20.0 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ35172.1 - 4.3e-07 30.1 0.0 0.0021 18.3 0.0 4.3 3 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3378 PF11858.8 EEQ35172.1 - 0.14 12.3 0.1 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) S1 PF00575.23 EEQ35173.1 - 9.2e-69 227.8 40.4 2.2e-14 53.6 0.2 12.8 12 2 0 12 12 12 10 S1 RNA binding domain Suf PF05843.14 EEQ35173.1 - 2e-06 28.0 7.4 0.003 17.6 0.0 4.2 2 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EEQ35173.1 - 2e-06 28.1 0.0 0.65 11.0 0.1 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 EEQ35173.1 - 3.1e-06 27.0 0.5 4.6 7.3 0.0 5.5 5 1 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain TPR_19 PF14559.6 EEQ35173.1 - 3.3e-06 27.5 0.0 0.01 16.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EEQ35173.1 - 0.0015 17.8 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 EEQ35173.1 - 0.0026 18.4 0.0 3.5 8.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ35173.1 - 0.027 14.5 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Cue1_U7BR PF18499.1 EEQ35173.1 - 0.032 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 TPR_8 PF13181.6 EEQ35173.1 - 0.037 14.2 0.0 0.48 10.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EEQ35173.1 - 0.045 14.0 0.0 12 6.4 0.0 3.1 2 0 0 2 2 2 0 PPR repeat TPR_6 PF13174.6 EEQ35173.1 - 0.048 14.3 0.5 27 5.7 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ35173.1 - 0.079 13.1 2.7 0.64 10.3 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Phage_lysozyme PF00959.19 EEQ35175.1 - 3.1e-14 53.4 0.0 4.2e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme UreD PF01774.17 EEQ35176.1 - 3e-77 259.3 0.0 3.6e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein RcpC PF16976.5 EEQ35176.1 - 0.032 14.3 0.3 0.22 11.5 0.1 2.2 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB STAG PF08514.11 EEQ35177.1 - 7.4e-40 135.4 0.9 7.4e-40 135.4 0.9 3.3 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.6 EEQ35177.1 - 0.00028 21.2 0.1 0.035 14.5 0.3 3.3 2 1 1 3 3 3 1 HEAT repeats eIF3_subunit PF08597.10 EEQ35177.1 - 0.0012 18.8 9.2 0.0012 18.8 9.2 4.7 5 0 0 5 5 5 1 Translation initiation factor eIF3 subunit HEAT PF02985.22 EEQ35177.1 - 0.042 14.1 0.7 2.8 8.4 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat CTD_bind PF04818.13 EEQ35177.1 - 0.19 12.6 0.2 14 6.6 0.0 3.6 3 0 0 3 3 3 0 RNA polymerase II-binding domain. GFA PF04828.14 EEQ35178.1 - 4.9e-14 52.4 3.1 6.8e-14 52.0 3.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Acatn PF13000.7 EEQ35179.1 - 1.2e-155 519.1 13.5 9.1e-82 275.3 8.0 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Pkinase PF00069.25 EEQ35180.1 - 1.9e-11 43.9 0.0 3.6e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35180.1 - 0.0028 17.0 0.0 0.014 14.7 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase MinE PF03776.14 EEQ35180.1 - 0.13 12.3 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE CENP-O PF09496.10 EEQ35181.1 - 3.5e-68 229.8 0.1 1.6e-67 227.6 0.0 1.8 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component VRP1 PF03538.14 EEQ35181.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein DUF4140 PF13600.6 EEQ35181.1 - 0.3 11.6 4.6 1.4 9.4 0.8 2.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.9 EEQ35181.1 - 0.49 10.4 3.0 7.3 6.6 0.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RFC1 PF08519.12 EEQ35183.1 - 0.26 11.4 5.2 5.5 7.1 0.6 2.3 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain DUF4715 PF15835.5 EEQ35183.1 - 1.8 8.6 9.4 0.11 12.5 3.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) Fungal_TACC PF12709.7 EEQ35183.1 - 3.2 8.3 12.9 0.048 14.1 1.7 2.7 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins NAM-associated PF14303.6 EEQ35183.1 - 8.9 7.0 22.5 0.046 14.4 4.4 3.1 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain Atg29_N PF18388.1 EEQ35184.1 - 1.7e-19 69.4 0.7 3e-19 68.6 0.7 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain DFP PF04127.15 EEQ35185.1 - 2.2e-12 47.2 0.0 7.5e-05 22.6 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Polysacc_deac_1 PF01522.21 EEQ35186.1 - 6.6e-12 45.4 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DEAD PF00270.29 EEQ35187.1 - 2.8e-27 95.6 0.0 4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ35187.1 - 3.3e-18 66.0 0.0 1e-15 58.0 0.1 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EEQ35187.1 - 0.00062 18.6 0.0 0.00085 18.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1929 PF09118.11 EEQ35188.1 - 8.6e-25 86.9 0.1 1.4e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Fumble PF03630.14 EEQ35189.1 - 6.6e-143 475.8 0.6 8.3e-143 475.5 0.6 1.1 1 0 0 1 1 1 1 Fumble GPI2 PF06432.11 EEQ35190.1 - 6.1e-77 258.8 9.7 6.9e-77 258.6 9.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Gly-zipper_YMGG PF13441.6 EEQ35190.1 - 0.73 9.6 4.1 0.22 11.3 1.2 1.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper CytochromB561_N PF09786.9 EEQ35190.1 - 2.6 6.9 13.9 4.5 6.2 13.9 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal Glyco_hydro_18 PF00704.28 EEQ35194.1 - 5.2e-20 72.4 0.0 1e-19 71.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Gly-rich_Ago1 PF12764.7 EEQ35194.1 - 2.1 9.2 7.1 0.24 12.2 2.2 1.9 2 0 0 2 2 2 0 Glycine-rich region of argonaut SLATT_5 PF18160.1 EEQ35196.1 - 2.6 7.3 9.4 0.37 10.1 0.7 3.0 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain family 5 Bunya_G2 PF03563.13 EEQ35196.1 - 2.7 7.2 7.7 4.9 6.3 7.7 1.4 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 AA_permease_2 PF13520.6 EEQ35198.1 - 1.1e-47 162.9 57.4 1.4e-47 162.5 57.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ35198.1 - 3.3e-21 75.5 49.6 4.8e-21 74.9 49.6 1.2 1 0 0 1 1 1 1 Amino acid permease HemY_N PF07219.13 EEQ35199.1 - 0.19 11.9 0.6 0.36 11.1 0.6 1.4 1 0 0 1 1 1 0 HemY protein N-terminus YqfD PF06898.11 EEQ35199.1 - 0.21 10.4 0.4 0.31 9.8 0.4 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Dynamin_N PF00350.23 EEQ35200.1 - 1.3e-27 96.9 0.0 3.3e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EEQ35200.1 - 1.2e-24 87.1 1.6 8.8e-20 71.1 0.5 2.6 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.23 EEQ35200.1 - 0.00013 22.1 0.1 0.0011 19.1 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase DNTTIP1_dimer PF18192.1 EEQ35200.1 - 0.0022 18.3 1.2 0.024 15.0 0.2 3.2 3 0 0 3 3 3 1 DNTTIP1 dimerisation domain AAA_27 PF13514.6 EEQ35200.1 - 0.098 12.2 0.0 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain CNDH2_C PF16858.5 EEQ35200.1 - 3.7 7.4 12.9 0.083 12.7 5.4 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term TFIIA PF03153.13 EEQ35200.1 - 7.7 6.4 22.8 0.61 10.0 17.3 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2254 PF10011.9 EEQ35201.1 - 0.042 12.7 0.6 0.056 12.2 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Col_cuticle_N PF01484.17 EEQ35201.1 - 1.6 8.9 6.2 3.7 7.7 6.2 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain 5_nucleotid_C PF02872.18 EEQ35202.1 - 4.3e-37 127.8 0.0 7.5e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain DUF5367 PF17329.2 EEQ35203.1 - 0.02 15.0 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5367) DUF5385 PF17359.2 EEQ35203.1 - 0.023 14.2 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Kinetochor_Ybp2 PF08568.10 EEQ35203.1 - 0.03 12.8 0.0 0.03 12.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin SIT PF15330.6 EEQ35203.1 - 0.04 14.4 0.0 0.054 13.9 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3267 PF11667.8 EEQ35203.1 - 0.066 13.5 0.0 0.085 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative zincin peptidase TMEM51 PF15345.6 EEQ35203.1 - 0.07 13.0 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF5305 PF17231.2 EEQ35203.1 - 0.085 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF5413 PF17434.2 EEQ35203.1 - 0.18 12.1 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5413) Aldedh PF00171.22 EEQ35204.1 - 2e-152 508.0 0.2 2.2e-152 507.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BTB PF00651.31 EEQ35205.1 - 0.038 14.2 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Gln-synt_C PF00120.24 EEQ35209.1 - 2.7e-58 197.6 0.0 9.8e-58 195.8 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 EEQ35209.1 - 2e-14 54.1 0.0 3.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Gln-synt_N_2 PF16952.5 EEQ35209.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain MFS_1 PF07690.16 EEQ35210.1 - 7.3e-37 127.1 21.6 7.3e-37 127.1 21.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ35210.1 - 9.5e-13 47.8 14.4 9.5e-13 47.8 14.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EEQ35210.1 - 0.0026 16.3 4.1 0.0044 15.5 4.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0016 PF01169.19 EEQ35213.1 - 2e-38 130.5 26.4 4e-19 68.7 10.9 2.5 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2070 PF09843.9 EEQ35213.1 - 0.033 12.5 2.1 0.06 11.6 2.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3357 PF11837.8 EEQ35213.1 - 0.17 12.4 6.5 6.8 7.2 0.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3357) Myb_DNA-binding PF00249.31 EEQ35214.1 - 0.00011 22.3 0.3 0.00034 20.8 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain TRF PF08558.10 EEQ35214.1 - 0.036 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) TFIIF_alpha PF05793.12 EEQ35214.1 - 0.49 8.9 6.0 1 7.9 6.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4611 PF15387.6 EEQ35214.1 - 1 9.6 6.0 4 7.7 6.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EEQ35214.1 - 2 7.7 3.6 3.4 6.9 3.6 1.3 1 0 0 1 1 1 0 NOA36 protein Annexin PF00191.20 EEQ35215.1 - 4.8e-14 52.2 1.5 0.0022 18.0 0.1 4.4 4 0 0 4 4 4 4 Annexin Ribosomal_L21e PF01157.18 EEQ35216.1 - 9.9e-47 157.0 3.9 9.9e-47 157.0 3.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e UPF0160 PF03690.13 EEQ35216.1 - 0.032 13.9 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) LRIF1 PF15741.5 EEQ35216.1 - 0.1 11.1 0.1 0.12 10.9 0.1 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF5486 PF17588.2 EEQ35216.1 - 0.39 10.6 3.6 1.7 8.6 0.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5486) S4 PF01479.25 EEQ35217.1 - 3.1e-12 46.0 1.1 3.1e-12 46.0 1.1 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EEQ35217.1 - 2e-06 28.6 0.2 4e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Bacillus_HBL PF05791.11 EEQ35218.1 - 0.0029 17.5 0.3 0.0029 17.5 0.3 1.8 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 EEQ35218.1 - 0.0033 16.4 21.7 0.022 13.7 7.9 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein Kre28 PF17097.5 EEQ35218.1 - 0.0042 16.1 8.2 0.013 14.5 8.2 1.7 1 1 0 1 1 1 1 Spindle pole body component DUF948 PF06103.11 EEQ35218.1 - 0.0059 16.8 3.8 0.043 14.1 0.3 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 EEQ35218.1 - 0.0082 16.4 4.2 0.0082 16.4 4.2 2.7 3 0 0 3 3 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3552 PF12072.8 EEQ35218.1 - 0.012 15.0 20.1 0.026 14.0 7.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Baculo_PEP_C PF04513.12 EEQ35218.1 - 0.022 14.8 3.9 0.056 13.5 0.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CC2-LZ PF16516.5 EEQ35218.1 - 0.035 14.5 10.7 0.93 9.9 2.2 2.7 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MAD PF05557.13 EEQ35218.1 - 0.055 11.8 17.6 0.07 11.5 17.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF1664 PF07889.12 EEQ35218.1 - 0.096 12.7 4.7 0.12 12.4 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 EEQ35218.1 - 0.099 12.2 9.7 0.07 12.7 7.2 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit BST2 PF16716.5 EEQ35218.1 - 0.22 12.1 15.4 0.33 11.6 5.3 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 AAA_13 PF13166.6 EEQ35218.1 - 0.22 10.1 8.6 0.3 9.7 8.6 1.2 1 0 0 1 1 1 0 AAA domain CEP63 PF17045.5 EEQ35218.1 - 0.36 10.7 23.3 0.46 10.3 7.3 2.4 2 1 1 3 3 2 0 Centrosomal protein of 63 kDa GreA_GreB_N PF03449.15 EEQ35218.1 - 0.4 10.9 15.0 2.8 8.2 2.4 2.9 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal HIP1_clath_bdg PF16515.5 EEQ35218.1 - 0.44 11.2 22.8 0.45 11.2 8.5 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3103 PF11301.8 EEQ35218.1 - 0.73 8.6 3.9 0.3 9.8 0.6 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3103) Prefoldin PF02996.17 EEQ35218.1 - 0.73 9.8 15.7 0.07 13.1 2.8 3.7 2 2 2 4 4 4 0 Prefoldin subunit FlaC_arch PF05377.11 EEQ35218.1 - 1 9.8 8.5 4 7.9 3.0 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 EEQ35218.1 - 1 9.8 18.2 2.6 8.5 18.2 1.6 1 1 0 1 1 1 0 Fez1 DUF1043 PF06295.12 EEQ35218.1 - 1.1 9.2 11.9 0.57 10.2 6.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) GAS PF13851.6 EEQ35218.1 - 1.5 8.1 18.4 3 7.2 5.2 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1216 PF06746.11 EEQ35218.1 - 1.7 8.7 7.9 0.53 10.3 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) Cep57_CLD_2 PF14197.6 EEQ35218.1 - 1.8 8.7 15.6 2.3 8.4 1.4 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Fib_alpha PF08702.10 EEQ35218.1 - 1.8 8.7 6.7 1.1 9.5 3.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 EEQ35218.1 - 2.6 6.8 3.9 3.2 6.5 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein STAT_alpha PF01017.20 EEQ35218.1 - 2.9 7.7 10.1 45 3.9 10.1 2.2 1 1 0 1 1 1 0 STAT protein, all-alpha domain GvpK PF05121.12 EEQ35218.1 - 3.4 7.8 9.2 1.7 8.7 0.1 3.3 2 1 1 3 3 3 0 Gas vesicle protein K Spc24 PF08286.11 EEQ35218.1 - 3.4 7.9 17.9 0.28 11.5 2.2 3.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 EEQ35218.1 - 3.5 7.6 17.9 0.82 9.7 4.8 3.5 3 1 0 3 3 3 0 Prefoldin subunit zf-C4H2 PF10146.9 EEQ35218.1 - 3.5 7.9 10.8 1.1 9.5 5.6 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein DUF16 PF01519.16 EEQ35218.1 - 4.9 7.7 11.3 11 6.6 3.8 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 ABC_tran_CTD PF16326.5 EEQ35218.1 - 6.9 7.0 24.4 0.56 10.5 1.9 4.4 1 1 3 4 4 4 0 ABC transporter C-terminal domain APG6_N PF17675.1 EEQ35218.1 - 9.5 6.8 27.0 8.1 7.0 13.1 2.9 2 1 1 3 3 2 0 Apg6 coiled-coil region SlyX PF04102.12 EEQ35218.1 - 9.5 6.9 16.2 7.7 7.2 1.4 3.8 1 1 1 3 3 3 0 SlyX Amidoligase_2 PF12224.8 EEQ35220.1 - 3.4e-07 30.2 0.0 0.017 14.8 0.0 2.8 2 1 0 2 2 2 2 Putative amidoligase enzyme VATC PF18716.1 EEQ35221.1 - 0.016 15.1 0.4 0.028 14.3 0.4 1.4 1 0 0 1 1 1 0 Vms1-associating treble clef domain Vps62 PF06101.11 EEQ35222.1 - 2.8e-05 22.6 0.1 0.0071 14.7 0.0 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 Septin PF00735.18 EEQ35223.1 - 1.6e-32 112.9 0.0 1e-12 48.0 0.0 3.1 3 0 0 3 3 3 3 Septin AAA_23 PF13476.6 EEQ35223.1 - 0.015 15.8 0.1 0.35 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Spem1 PF15670.5 EEQ35223.1 - 1.1 8.8 0.0 1.1 8.8 0.0 2.5 3 0 0 3 3 3 0 Spermatid maturation protein 1 Mito_carr PF00153.27 EEQ35224.1 - 2e-74 245.6 1.8 1e-25 89.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EEQ35224.1 - 0.17 12.1 0.0 11 6.3 0.0 3.0 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Conotoxin PF02950.17 EEQ35225.1 - 6.4 7.9 6.5 2 9.5 0.5 2.6 3 0 0 3 3 3 0 Conotoxin SecE PF00584.20 EEQ35228.1 - 9.8e-14 51.0 0.0 1.2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.22 EEQ35229.1 - 6.3e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EEQ35230.1 - 1.2e-17 64.0 19.2 0.00098 19.9 0.2 7.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ35230.1 - 1.8e-05 24.9 0.1 0.11 12.8 0.0 4.0 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EEQ35230.1 - 2e-05 23.3 2.8 0.15 10.6 0.0 4.2 2 1 0 4 4 4 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 EEQ35230.1 - 0.0026 18.2 1.5 3.4 8.3 0.0 4.5 4 0 0 4 4 4 1 PQQ-like domain PD40 PF07676.12 EEQ35230.1 - 0.02 14.9 1.3 0.31 11.0 0.0 3.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat NOA36 PF06524.12 EEQ35230.1 - 9 5.5 8.1 14 4.9 8.1 1.2 1 0 0 1 1 1 0 NOA36 protein PX PF00787.24 EEQ35231.1 - 3.1e-27 94.8 0.2 3.7e-27 94.6 0.2 1.1 1 0 0 1 1 1 1 PX domain Myb_DNA-bind_6 PF13921.6 EEQ35232.1 - 7.4e-15 55.0 0.0 1.2e-07 31.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EEQ35232.1 - 8.2e-13 48.3 0.1 1.2e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EEQ35232.1 - 0.0037 17.3 0.0 3.7 7.6 0.0 2.4 2 0 0 2 2 2 2 SLIDE RasGEF PF00617.19 EEQ35234.1 - 7.2e-07 29.6 0.0 1.7e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain Spot_14 PF07084.12 EEQ35234.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 DNA_pol_B PF00136.21 EEQ35239.1 - 1.4e-101 340.5 0.0 1.8e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EEQ35239.1 - 7.8e-19 68.0 0.0 2.8e-15 56.3 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EEQ35239.1 - 1.6e-17 63.7 8.0 1.6e-17 63.7 8.0 2.4 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DUF1744 PF08490.12 EEQ35239.1 - 0.013 14.0 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Slu7 PF11708.8 EEQ35240.1 - 3.3e-83 279.5 17.6 3.3e-83 279.5 17.6 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EEQ35240.1 - 0.05 13.3 0.7 0.11 12.2 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L37e PF01907.19 EEQ35241.1 - 3.5e-28 97.5 9.0 5.1e-28 97.0 9.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EEQ35241.1 - 0.013 15.5 0.9 0.021 14.8 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 EEQ35241.1 - 0.18 11.7 2.8 0.33 10.8 2.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ELP6 PF09807.9 EEQ35242.1 - 7e-13 48.6 0.0 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Elongation complex protein 6 ATPase PF06745.13 EEQ35242.1 - 0.16 11.3 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 KaiC RdRP PF05183.12 EEQ35243.1 - 1e-193 645.2 0.0 1.4e-193 644.8 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.21 EEQ35244.1 - 1.5e-136 455.8 43.9 1.9e-136 455.5 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ35244.1 - 2.4e-38 132.1 46.7 3e-38 131.8 46.7 1.1 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.20 EEQ35246.1 - 9e-117 390.0 18.8 1.1e-116 389.7 18.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EEQ35246.1 - 8.9e-08 31.8 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EEQ35246.1 - 3.7e-05 24.1 14.5 3.9e-05 24.0 3.1 2.9 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily FAD-oxidase_C PF02913.19 EEQ35247.1 - 1e-59 202.2 0.0 1.3e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EEQ35247.1 - 1.6e-34 118.6 0.0 5.3e-34 116.9 0.0 2.0 1 0 0 1 1 1 1 FAD binding domain Bacteriocin_IIc PF10439.9 EEQ35247.1 - 0.46 10.6 4.2 2.2 8.4 4.2 2.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Ribosomal_S4e PF00900.20 EEQ35248.1 - 1.5e-36 124.2 0.4 3e-36 123.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EEQ35248.1 - 2.2e-24 84.8 0.1 4.1e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EEQ35248.1 - 1.2e-18 66.9 7.0 2.4e-18 66.0 7.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EEQ35248.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EEQ35248.1 - 0.006 16.5 1.0 0.006 16.5 1.0 3.1 3 0 0 3 3 3 1 KOW motif MATalpha_HMGbox PF04769.12 EEQ35250.1 - 2.1e-33 115.4 0.0 3.4e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box DUF3306 PF11748.8 EEQ35250.1 - 2.7 8.9 8.5 4.5 8.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Exo_endo_phos PF03372.23 EEQ35252.1 - 7.7e-15 55.0 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EEQ35252.1 - 0.0027 17.5 0.0 0.34 10.8 0.0 2.6 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase zf-GRF PF06839.12 EEQ35252.1 - 0.0041 17.2 1.2 0.011 15.8 1.2 1.8 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.15 EEQ35253.1 - 6.6e-43 145.7 1.9 1.3e-42 144.8 1.9 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa ANTH PF07651.16 EEQ35254.1 - 7.2e-76 254.8 0.0 7.2e-76 254.8 0.0 2.8 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 EEQ35254.1 - 1.6e-56 190.8 8.3 1.6e-56 190.8 8.3 6.1 3 2 1 6 6 6 2 I/LWEQ domain MMM1 PF10296.9 EEQ35255.1 - 3.9e-05 22.9 0.0 0.00015 21.0 0.0 1.8 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 EEQ35255.1 - 0.11 13.0 0.1 0.76 10.2 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Tyrosinase PF00264.20 EEQ35255.1 - 0.24 11.7 0.8 0.5 10.6 0.8 1.5 1 0 0 1 1 1 0 Common central domain of tyrosinase SKG6 PF08693.10 EEQ35257.1 - 4.2e-05 22.8 0.5 7.9e-05 22.0 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Trp_oprn_chp PF09534.10 EEQ35257.1 - 0.0018 18.1 1.7 0.0028 17.5 1.7 1.2 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Keratin PF02422.16 EEQ35257.1 - 0.017 14.8 2.2 0.017 14.8 2.2 2.2 1 1 1 2 2 2 0 Keratin TMEM51 PF15345.6 EEQ35257.1 - 0.058 13.2 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3318 PF11780.8 EEQ35257.1 - 0.15 12.0 0.4 0.23 11.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) DUF2298 PF10060.9 EEQ35257.1 - 0.23 10.1 0.1 0.32 9.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) DUF963 PF06131.11 EEQ35257.1 - 1 8.9 6.4 0.17 11.3 1.0 2.1 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Med12 PF09497.10 EEQ35258.1 - 2.4e-28 98.2 0.2 7.8e-28 96.6 0.2 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 EEQ35258.1 - 3.8e-05 22.7 0.0 0.0028 16.6 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain FAM86 PF14904.6 EEQ35258.1 - 0.14 12.2 0.2 0.48 10.6 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function CIA30 PF08547.12 EEQ35259.1 - 9.1e-39 133.0 0.0 1.8e-24 86.5 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.18 EEQ35260.1 - 2.3e-94 315.7 0.0 2.7e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase ANAPC5 PF12862.7 EEQ35261.1 - 2.7e-33 113.9 3.2 3.5e-33 113.5 1.2 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 EEQ35261.1 - 0.00091 19.7 6.9 4.9 7.7 1.4 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ35261.1 - 0.0025 17.2 3.8 0.0025 17.2 3.8 1.8 2 0 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 EEQ35261.1 - 0.0047 17.2 6.8 24 5.3 0.1 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat SUI1 PF01253.22 EEQ35262.1 - 4.3e-28 97.7 3.9 5.6e-28 97.3 3.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 EEQ35262.1 - 0.084 13.1 0.4 0.13 12.5 0.4 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain EOS1 PF12326.8 EEQ35263.1 - 9.7e-13 48.4 14.0 1e-12 48.4 11.8 1.8 1 1 1 2 2 2 1 N-glycosylation protein MBA1 PF07961.11 EEQ35265.1 - 2.4e-11 43.2 0.1 5.2e-11 42.1 0.1 1.5 1 1 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 EEQ35265.1 - 0.00043 20.4 0.1 0.0019 18.3 0.1 1.9 1 1 0 1 1 1 1 Tim44-like domain SSF PF00474.17 EEQ35266.1 - 0.00071 18.5 25.8 0.0035 16.3 25.8 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family RhoGAP PF00620.27 EEQ35267.1 - 1.4e-48 164.5 0.0 3.3e-48 163.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EEQ35267.1 - 2.4e-14 53.3 1.5 2.7e-13 50.0 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 EEQ35267.1 - 0.75 9.1 9.5 1.2 8.4 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4472 PF14739.6 EEQ35267.1 - 3.6 8.4 6.7 24 5.7 6.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) OmpH PF03938.14 EEQ35267.1 - 7.1 7.0 17.7 13 6.2 16.4 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ABM PF03992.16 EEQ35268.1 - 6.5e-14 51.8 0.0 7.7e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SchA_CurD PF04486.12 EEQ35268.1 - 0.15 12.1 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 SchA/CurD like domain Ras PF00071.22 EEQ35269.1 - 2.1e-55 186.8 0.0 2.4e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ35269.1 - 1.6e-21 76.7 0.0 2.4e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ35269.1 - 5e-08 32.6 0.0 6.3e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 EEQ35270.1 - 4.2e-11 42.5 1.6 5.4e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.6 EEQ35271.1 - 1.1e-76 257.5 0.8 1.3e-76 257.3 0.8 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EEQ35271.1 - 7.2e-05 22.6 0.0 8.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-T_C PF15511.6 EEQ35272.1 - 9.9e-30 102.8 0.0 1.7e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EEQ35272.1 - 8.5e-07 29.3 0.1 1.6e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EEQ35272.1 - 7.4e-05 23.1 0.1 7.4e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEQ35272.1 - 0.0037 17.5 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNA_pol_Rpc4 PF05132.14 EEQ35272.1 - 0.0046 17.4 0.7 0.012 16.1 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase III RPC4 SURF1 PF02104.15 EEQ35273.1 - 2e-46 158.4 0.0 2.7e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.20 EEQ35274.1 - 4.1e-10 39.7 0.0 7.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain CDC45 PF02724.14 EEQ35274.1 - 2.6 6.2 8.0 4 5.6 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EEQ35274.1 - 2.7 6.7 3.5 4.5 5.9 3.5 1.3 1 0 0 1 1 1 0 Presenilin MSA-2c PF12238.8 EEQ35274.1 - 3 7.8 14.2 0.021 14.9 5.9 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF2076 PF09849.9 EEQ35275.1 - 1.2e-08 35.3 11.8 1.4e-08 35.1 11.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EEQ35275.1 - 4.7e-06 26.6 2.9 7.4e-06 26.0 2.9 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EEQ35275.1 - 0.05 13.6 0.3 0.082 12.9 0.3 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3275 PF11679.8 EEQ35275.1 - 1.3 9.0 6.2 1.1 9.2 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Totivirus_coat PF05518.11 EEQ35275.1 - 2.9 5.8 11.0 3.4 5.6 11.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein Sas10_Utp3 PF04000.15 EEQ35276.1 - 4.3e-13 49.7 0.6 4.3e-13 49.7 0.6 2.4 2 1 0 2 2 2 1 Sas10/Utp3/C1D family CDC45 PF02724.14 EEQ35276.1 - 0.1 10.9 24.2 0.12 10.7 24.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EEQ35276.1 - 9.5 4.3 33.0 13 3.9 33.0 1.1 1 0 0 1 1 1 0 Nop14-like family ApbA_C PF08546.11 EEQ35277.1 - 2.3e-31 108.6 0.2 3.4e-31 108.0 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EEQ35277.1 - 1.3e-22 80.1 0.0 3.4e-21 75.5 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Coq4 PF05019.13 EEQ35278.1 - 1.8e-96 321.7 0.0 2.1e-96 321.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.20 EEQ35279.1 - 8.4e-36 122.6 10.9 1.1e-35 122.3 10.9 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Sec2p PF06428.11 EEQ35280.1 - 2.2e-10 40.3 5.9 1.1e-09 38.1 4.6 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p BBP1_C PF15272.6 EEQ35280.1 - 0.099 12.5 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal PRP21_like_P PF12230.8 EEQ35281.1 - 3.8e-56 190.4 5.6 2.1e-30 106.2 0.9 2.2 2 0 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EEQ35281.1 - 4e-27 94.0 1.0 1.2e-16 60.4 0.5 2.4 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 EEQ35281.1 - 0.022 14.4 0.6 0.053 13.1 0.6 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-Dof PF02701.15 EEQ35281.1 - 0.27 11.4 1.2 8.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Dof domain, zinc finger UPF0547 PF10571.9 EEQ35281.1 - 0.3 11.2 1.5 0.78 9.9 1.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 PMT PF02366.18 EEQ35282.1 - 8.1e-69 231.9 6.4 8.1e-69 231.9 6.4 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 EEQ35282.1 - 1.6e-47 161.8 0.0 2.9e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 MIR domain PMT_4TMC PF16192.5 EEQ35282.1 - 4.9e-29 101.4 13.0 5.9e-24 84.8 3.8 2.9 2 1 1 3 3 3 2 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 EEQ35282.1 - 2.8 8.1 16.0 0.08 13.1 6.1 3.0 3 1 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DHHC PF01529.20 EEQ35284.1 - 7.3e-36 123.2 5.7 7.3e-36 123.2 5.7 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase SET PF00856.28 EEQ35285.1 - 1.7e-14 54.6 2.8 1.4e-13 51.6 0.2 3.1 2 1 0 2 2 2 1 SET domain AWS PF17907.1 EEQ35285.1 - 5.5e-08 32.7 8.2 5.5e-08 32.7 8.2 2.2 3 0 0 3 3 3 1 AWS domain Complex1_LYR PF05347.15 EEQ35286.1 - 5.3e-16 58.4 4.8 5.3e-16 58.4 4.8 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEQ35286.1 - 0.00099 19.8 4.1 0.0021 18.8 4.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like PMC2NT PF08066.12 EEQ35287.1 - 0.018 15.7 0.2 0.055 14.2 0.0 1.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain ATP-sulfurylase PF01747.17 EEQ35292.1 - 8e-81 270.5 0.0 1.2e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EEQ35292.1 - 6.2e-58 195.2 0.0 9.8e-58 194.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EEQ35292.1 - 1.9e-49 167.4 0.0 3.3e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain PAPS_reduct PF01507.19 EEQ35293.1 - 1.2e-43 149.1 0.0 1.8e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 EEQ35294.1 - 1.2e-23 84.5 0.1 1.8e-23 84.0 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ35294.1 - 5.7e-21 75.8 0.9 7.6e-21 75.4 0.9 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEQ35294.1 - 6.9e-09 35.8 0.1 8.1e-08 32.3 0.1 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ35294.1 - 0.00029 21.0 0.1 0.005 16.9 0.1 2.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EEQ35294.1 - 0.00067 19.1 0.0 0.044 13.2 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase S6PP PF05116.13 EEQ35294.1 - 0.055 13.0 0.2 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DUF705 PF05152.12 EEQ35294.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) LIAS_N PF16881.5 EEQ35295.1 - 6.7e-26 90.8 0.0 1.4e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EEQ35295.1 - 7.2e-14 52.5 0.0 1.7e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.32 EEQ35296.1 - 1e-10 42.0 5.5 1.9e-05 25.3 0.0 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ35296.1 - 0.004 17.4 0.0 11 6.4 0.0 4.5 2 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EEQ35296.1 - 0.021 14.4 0.0 2.5 7.6 0.0 2.3 1 1 1 2 2 2 0 PQQ-like domain Gryzun-like PF12742.7 EEQ35296.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Nefa_Nip30_N PF10187.9 EEQ35296.1 - 1.4 9.3 8.0 1 9.7 5.9 1.7 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 FlxA PF14282.6 EEQ35296.1 - 4.2 7.4 9.0 9.3 6.3 9.0 1.6 1 0 0 1 1 1 0 FlxA-like protein DeoC PF01791.9 EEQ35299.1 - 2.5e-16 60.0 2.9 3.6e-16 59.5 2.9 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 EEQ35299.1 - 0.0002 20.7 1.3 0.00043 19.6 0.9 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ComA PF02679.15 EEQ35299.1 - 0.092 12.2 0.2 0.43 10.0 0.0 2.1 2 2 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) Glyoxalase_4 PF13669.6 EEQ35299.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SelK_SelG PF10961.8 EEQ35300.1 - 1.6e-06 28.6 12.8 0.00031 21.3 12.8 2.1 1 1 0 1 1 1 1 Selenoprotein SelK_SelG GRP PF07172.11 EEQ35300.1 - 0.00026 21.6 1.7 0.00035 21.2 1.7 1.1 1 0 0 1 1 1 1 Glycine rich protein family R3H PF01424.22 EEQ35300.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 R3H domain Pinin_SDK_N PF04697.13 EEQ35300.1 - 2 9.1 4.3 2.6 8.7 4.3 1.2 1 0 0 1 1 1 0 pinin/SDK conserved region TP_methylase PF00590.20 EEQ35301.1 - 9.9e-47 159.6 0.0 1.6e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EEQ35301.1 - 1.3e-12 48.0 0.0 2.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EEQ35301.1 - 2.5e-08 33.4 0.0 5e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EEQ35301.1 - 0.0036 16.7 0.3 0.0036 16.7 0.3 2.1 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central PCI PF01399.27 EEQ35302.1 - 6.4e-23 81.3 0.0 2.5e-22 79.4 0.0 2.0 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 EEQ35302.1 - 2e-16 59.8 1.9 5.3e-16 58.4 1.9 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain FSH1 PF03959.13 EEQ35303.1 - 4.4e-66 222.6 0.0 6.8e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EEQ35303.1 - 1.2e-05 26.0 0.6 1.8e-05 25.5 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EEQ35303.1 - 0.021 14.4 0.0 0.18 11.3 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EEQ35303.1 - 0.11 11.8 0.0 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EEQ35303.1 - 0.21 11.4 0.0 11 5.8 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Acyltransferase PF01553.21 EEQ35304.1 - 0.084 12.5 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Acyltransferase Capsid_NCLDV PF04451.12 EEQ35306.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Ribosomal_S27e PF01667.17 EEQ35307.1 - 1e-28 98.8 6.7 1.3e-28 98.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 EEQ35307.1 - 0.26 11.3 6.1 2 8.4 4.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type PTase_Orf2 PF11468.8 EEQ35308.1 - 0.016 14.6 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 CDP-OH_P_transf PF01066.21 EEQ35309.1 - 2.1e-14 54.0 0.0 2.1e-14 54.0 0.0 3.1 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.13 EEQ35310.1 - 3.4e-41 139.6 0.4 1.3e-29 102.4 0.1 2.3 2 0 0 2 2 2 2 NIPSNAP DUF1180 PF06679.12 EEQ35310.1 - 4 7.8 7.7 6.2 7.2 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MSA-2c PF12238.8 EEQ35310.1 - 9.5 6.2 7.0 16 5.4 7.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Putative_PNPOx PF01243.20 EEQ35311.1 - 4.3e-12 46.1 0.0 8.3e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EEQ35311.1 - 0.051 13.6 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Peptidase_C65 PF10275.9 EEQ35312.1 - 3e-39 135.0 0.3 4.3e-39 134.4 0.3 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain Pentapeptide_3 PF13576.6 EEQ35312.1 - 0.15 12.2 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) DUF5337 PF17272.2 EEQ35313.1 - 1.3 8.9 8.5 1.1 9.2 1.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5337) PCI PF01399.27 EEQ35314.1 - 2.3e-16 60.2 0.2 6.9e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain Ank_2 PF12796.7 EEQ35315.1 - 1e-154 503.5 6.5 3.3e-17 62.8 0.0 11.7 3 2 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ35315.1 - 5.5e-129 419.0 35.3 1.2e-09 38.6 0.0 19.2 3 1 17 21 21 21 21 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ35315.1 - 4.3e-119 373.9 29.5 2.1e-05 24.5 0.0 25.0 25 0 0 25 25 25 23 Ankyrin repeat Ank PF00023.30 EEQ35315.1 - 1.7e-116 376.1 33.7 9.5e-06 25.8 0.0 23.9 24 0 0 24 24 24 21 Ankyrin repeat Ank_5 PF13857.6 EEQ35315.1 - 5.9e-109 354.7 34.7 1.1e-10 41.6 0.1 18.5 3 2 18 21 21 21 21 Ankyrin repeats (many copies) Patatin PF01734.22 EEQ35315.1 - 2.9e-22 79.9 0.0 7.2e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_22 PF13401.6 EEQ35315.1 - 0.0038 17.5 0.0 0.0094 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EEQ35315.1 - 0.018 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Vps23_core PF09454.10 EEQ35315.1 - 0.14 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Vps23 core domain DUF1187 PF06688.11 EEQ35315.1 - 1.8 8.9 19.6 56 4.2 0.1 7.9 8 0 0 8 8 8 0 Protein of unknown function (DUF1187) CWC25 PF12542.8 EEQ35316.1 - 1.4e-25 90.1 0.4 1.4e-25 90.1 0.4 3.9 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EEQ35316.1 - 1.7e-13 50.5 10.0 1.7e-13 50.5 10.0 4.6 4 2 2 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.22 EEQ35317.1 - 9.8e-36 122.8 0.1 8.7e-35 119.7 0.1 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EEQ35317.1 - 4.2e-19 68.9 0.1 1.2e-18 67.4 0.1 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ35317.1 - 9.7e-06 25.1 0.4 0.00039 19.9 0.4 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ35317.1 - 0.00069 19.0 0.0 0.0026 17.1 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ35317.1 - 0.0015 18.6 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ35317.1 - 0.027 14.4 0.0 1.9 8.4 0.0 2.4 1 1 1 2 2 2 0 RsgA GTPase G-alpha PF00503.20 EEQ35317.1 - 0.031 13.4 0.2 0.34 10.0 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 EEQ35317.1 - 0.12 12.8 0.1 0.26 11.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 EEQ35317.1 - 0.13 11.7 0.1 0.3 10.5 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 EEQ35317.1 - 0.14 11.5 0.1 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein BPL_LplA_LipB PF03099.19 EEQ35318.1 - 4.5e-05 23.4 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family APH PF01636.23 EEQ35319.1 - 2.6e-12 47.2 0.3 9.8e-12 45.3 0.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ35319.1 - 4.9e-06 26.3 0.0 1.8e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Ank_2 PF12796.7 EEQ35320.1 - 1.9e-20 73.2 1.7 3.7e-07 30.7 0.3 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ35320.1 - 4.7e-16 58.9 2.0 7.8e-07 29.5 0.6 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EEQ35320.1 - 1.7e-15 56.7 5.6 0.0036 17.7 0.1 4.7 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EEQ35320.1 - 3.9e-13 49.3 3.2 0.0038 17.5 0.3 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ35320.1 - 1.6e-12 46.4 0.4 0.019 15.5 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat polyprenyl_synt PF00348.17 EEQ35321.1 - 9e-67 224.8 0.0 9.9e-66 221.4 0.0 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase Rpn3_C PF08375.11 EEQ35322.1 - 9.9e-26 90.0 0.6 9.9e-26 90.0 0.6 2.4 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EEQ35322.1 - 5.5e-21 75.1 0.5 2e-20 73.3 0.0 2.2 3 0 0 3 3 3 1 PCI domain DASH_Spc34 PF08657.10 EEQ35324.1 - 4.9e-44 151.0 3.5 1.1e-21 77.8 1.3 2.1 1 1 1 2 2 2 2 DASH complex subunit Spc34 Uds1 PF15456.6 EEQ35324.1 - 0.0079 16.4 4.1 0.0079 16.4 4.1 1.8 1 1 0 2 2 2 1 Up-regulated During Septation DASH_Spc19 PF08287.11 EEQ35324.1 - 0.012 15.5 2.1 0.024 14.5 2.1 1.5 1 0 0 1 1 1 0 Spc19 Nsp1_C PF05064.13 EEQ35324.1 - 0.02 14.7 0.8 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF3381 PF11861.8 EEQ35324.1 - 0.06 13.1 2.5 0.26 11.1 2.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Spectrin PF00435.21 EEQ35324.1 - 0.096 13.2 0.9 8.8 6.9 0.1 2.4 2 0 0 2 2 2 0 Spectrin repeat Prefoldin_2 PF01920.20 EEQ35324.1 - 0.27 11.2 3.0 6.3 6.8 0.3 2.5 3 0 0 3 3 3 0 Prefoldin subunit PRKG1_interact PF15898.5 EEQ35324.1 - 0.84 10.6 7.1 0.49 11.3 3.7 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ATG16 PF08614.11 EEQ35324.1 - 1.5 9.0 7.9 9.2 6.4 0.8 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF3287 PF11690.8 EEQ35324.1 - 3.5 7.4 6.0 11 5.8 0.4 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3287) DUF465 PF04325.13 EEQ35324.1 - 7.7 6.6 8.7 0.34 11.0 1.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF465) F-box PF00646.33 EEQ35325.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EEQ35325.1 - 0.0086 16.0 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like TFIID_20kDa PF03847.13 EEQ35326.1 - 1.1e-23 83.5 0.0 1.9e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EEQ35326.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CorA PF01544.18 EEQ35327.1 - 1.7e-13 50.6 1.3 2.9e-13 49.8 1.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UDP-g_GGTase PF06427.11 EEQ35327.1 - 0.089 12.9 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF1203 PF06718.11 EEQ35328.1 - 5e-37 126.7 0.0 6.2e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1203) Kdo PF06293.14 EEQ35329.1 - 8.9e-06 25.2 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEQ35329.1 - 0.0093 15.4 1.3 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EEQ35329.1 - 0.051 13.5 0.0 0.051 13.5 0.0 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pinin_SDK_memA PF04696.13 EEQ35329.1 - 0.11 12.5 24.1 0.27 11.3 24.1 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Choline_kinase PF01633.20 EEQ35329.1 - 0.13 11.8 1.9 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Spt20 PF12090.8 EEQ35329.1 - 0.25 10.9 10.5 0.49 10.0 10.5 1.4 1 0 0 1 1 1 0 Spt20 family DUF2828 PF11443.8 EEQ35329.1 - 0.49 8.4 7.3 0.7 7.9 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 EEQ35329.1 - 4 6.3 6.6 7.8 5.4 6.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Borrelia_P83 PF05262.11 EEQ35329.1 - 4.4 5.7 20.3 6.5 5.1 20.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SpoIIP PF07454.11 EEQ35329.1 - 4.5 6.6 8.7 8.4 5.8 8.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 EEQ35329.1 - 5.6 6.7 15.6 9.4 6.0 15.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.14 EEQ35329.1 - 7.8 6.2 11.4 18 5.1 11.4 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein p450 PF00067.22 EEQ35331.1 - 2.4e-64 217.8 0.0 3e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EEQ35332.1 - 1.3e-70 238.4 0.0 1.7e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SQHop_cyclase_C PF13243.6 EEQ35334.1 - 4.2e-31 108.2 0.0 4.3e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 EEQ35334.1 - 4.6e-12 45.5 9.8 1.9e-05 24.3 0.8 3.4 3 1 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EEQ35334.1 - 0.00011 21.4 0.1 0.027 13.6 0.0 2.9 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 EEQ35334.1 - 0.00022 20.4 0.1 0.0028 16.7 0.0 2.1 1 1 0 1 1 1 1 A-macroglobulin TED domain Pec_lyase PF09492.10 EEQ35334.1 - 0.00022 20.6 0.0 3 7.1 0.0 3.0 2 1 1 3 3 3 3 Pectic acid lyase DMA PF03474.14 EEQ35334.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif adh_short PF00106.25 EEQ35335.1 - 9.2e-39 132.9 3.1 1.3e-38 132.5 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ35335.1 - 3.9e-33 115.0 3.2 5.1e-33 114.6 3.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ35335.1 - 1.6e-07 31.4 0.6 2.9e-07 30.6 0.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ35335.1 - 0.052 13.0 0.6 0.11 11.9 0.2 1.6 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EEQ35335.1 - 0.22 11.4 1.4 0.41 10.5 1.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 EEQ35336.1 - 2.3e-63 214.5 0.0 2.9e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_9 PF12781.7 EEQ35336.1 - 0.045 12.9 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 ATP-binding dynein motor region Transferase PF02458.15 EEQ35337.1 - 4.3e-24 84.9 0.0 6.5e-10 38.2 0.0 3.0 3 0 0 3 3 3 3 Transferase family Epimerase PF01370.21 EEQ35338.1 - 1.5e-18 67.2 0.0 1.9e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ35338.1 - 1.5e-12 47.1 0.0 1.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EEQ35338.1 - 1.9e-08 34.4 0.1 3e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EEQ35338.1 - 1.9e-07 30.8 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EEQ35338.1 - 1.5e-06 27.6 0.0 5.6e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EEQ35338.1 - 0.00013 21.2 0.2 0.00018 20.7 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EEQ35338.1 - 0.0017 17.9 0.2 0.0027 17.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Creatininase PF02633.14 EEQ35338.1 - 0.069 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Creatinine amidohydrolase NmrA PF05368.13 EEQ35338.1 - 0.13 11.8 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.22 EEQ35339.1 - 3.5e-49 167.8 0.0 4.3e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EEQ35341.1 - 1.4e-05 24.3 0.4 0.00092 18.3 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain RsbU_N PF08673.10 EEQ35341.1 - 0.11 12.5 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain MFS_1 PF07690.16 EEQ35342.1 - 2.8e-30 105.4 58.1 1.3e-28 100.0 54.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ35342.1 - 7.1e-07 28.4 9.6 7.1e-07 28.4 9.6 3.4 3 1 0 3 3 3 1 Sugar (and other) transporter PSI_PSAK PF01241.18 EEQ35342.1 - 0.11 12.5 2.4 0.28 11.2 0.0 2.9 4 0 0 4 4 4 0 Photosystem I psaG / psaK FMO-like PF00743.19 EEQ35343.1 - 2.6e-07 29.4 0.0 0.01 14.3 0.0 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EEQ35343.1 - 0.00039 19.8 0.0 0.0053 16.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ35343.1 - 0.053 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Exonuc_VII_L PF02601.15 EEQ35344.1 - 0.012 15.2 18.3 0.022 14.3 8.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EEQ35344.1 - 0.16 11.3 29.0 0.69 9.2 13.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FapA PF03961.13 EEQ35344.1 - 1.7 7.1 22.1 0.14 10.7 2.8 2.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A LMBR1 PF04791.16 EEQ35344.1 - 2.9 6.7 10.9 0.082 11.8 3.3 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein Filament PF00038.21 EEQ35344.1 - 6.9 6.2 37.9 0.54 9.8 12.6 2.9 2 1 0 2 2 2 0 Intermediate filament protein eIF2A PF08662.11 EEQ35345.1 - 5e-84 281.0 0.1 8e-83 277.1 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EEQ35345.1 - 0.012 16.5 0.4 1.7 9.6 0.1 3.9 3 1 1 4 4 4 0 WD domain, G-beta repeat NAD_binding_6 PF08030.12 EEQ35346.1 - 1.8e-33 115.9 0.0 2.9e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EEQ35346.1 - 1.6e-23 82.8 0.1 6.3e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EEQ35346.1 - 8.5e-14 51.8 11.6 8.5e-14 51.8 11.6 2.4 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 EEQ35346.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EEQ35346.1 - 0.052 14.2 0.0 0.17 12.6 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF3742 PF12553.8 EEQ35346.1 - 0.2 11.7 0.3 0.65 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) Polyketide_cyc2 PF10604.9 EEQ35347.1 - 5.6e-05 23.4 0.1 6.9e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FAD_binding_4 PF01565.23 EEQ35348.1 - 1e-21 77.1 1.1 1.8e-21 76.3 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 EEQ35349.1 - 9.1e-31 107.1 0.0 1.6e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EEQ35350.1 - 1.7e-11 44.0 0.0 2.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35350.1 - 3e-08 33.3 0.0 8e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ35350.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ35350.1 - 0.004 17.1 0.1 0.0057 16.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ35350.1 - 0.057 12.7 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EEQ35350.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EEQ35350.1 - 0.072 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EEQ35350.1 - 0.11 11.2 0.0 0.24 10.2 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Pkinase_fungal PF17667.1 EEQ35351.1 - 3.7e-95 319.1 0.0 4.5e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EEQ35351.1 - 2.2e-09 37.1 0.0 2.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EEQ35351.1 - 0.23 11.0 0.0 0.42 10.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Rubis-subs-bind PF09273.11 EEQ35353.1 - 5.2e-21 75.7 0.0 8.5e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EEQ35353.1 - 4.2e-12 46.8 0.0 7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 EEQ35353.1 - 3.6e-09 36.6 13.3 6.5e-09 35.7 13.3 1.5 1 0 0 1 1 1 1 MYND finger DUF1582 PF07621.11 EEQ35353.1 - 0.14 12.1 0.8 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) Ribul_P_3_epim PF00834.19 EEQ35354.1 - 0.062 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family HeLo PF14479.6 EEQ35355.1 - 3.8e-42 144.4 0.1 4.6e-42 144.2 0.1 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.12 EEQ35356.1 - 5.3e-29 101.3 0.0 8.7e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 EEQ35356.1 - 1e-08 35.7 0.7 3.5e-08 34.0 0.7 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat AAA_16 PF13191.6 EEQ35356.1 - 0.00044 20.7 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ35356.1 - 0.00059 20.1 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EEQ35356.1 - 0.0037 16.6 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EEQ35356.1 - 0.0043 17.4 0.0 0.018 15.4 0.0 2.1 1 0 0 1 1 1 1 RNA helicase ANAPC4_WD40 PF12894.7 EEQ35356.1 - 0.0068 16.7 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ResIII PF04851.15 EEQ35356.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEQ35356.1 - 0.037 14.3 0.0 0.078 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EEQ35356.1 - 0.047 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EEQ35356.1 - 0.12 11.6 1.0 2.8 7.1 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain PMBR PF09373.10 EEQ35356.1 - 0.27 11.4 0.7 1 9.7 0.2 2.3 2 0 0 2 2 2 0 Pseudomurein-binding repeat APH PF01636.23 EEQ35357.1 - 2.6e-09 37.4 0.1 3.3e-08 33.8 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Gon7 PF08738.10 EEQ35359.1 - 0.21 11.7 2.1 0.25 11.4 0.0 2.1 2 1 0 2 2 2 0 Gon7 family DUF2841 PF11001.8 EEQ35360.1 - 1.7e-52 176.7 0.1 2.9e-52 175.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) CorA PF01544.18 EEQ35360.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PAH PF02671.21 EEQ35364.1 - 1.4e-11 44.4 0.0 2.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat p450 PF00067.22 EEQ35366.1 - 3.2e-32 111.9 0.0 2.6e-25 89.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EEQ35367.1 - 1.4e-34 119.7 0.0 1.7e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Phage_min_tail PF05939.13 EEQ35367.1 - 0.17 12.3 0.0 2 8.9 0.0 2.2 2 0 0 2 2 2 0 Phage minor tail protein 3Beta_HSD PF01073.19 EEQ35368.1 - 5.2e-49 166.7 0.0 6.1e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EEQ35368.1 - 5.7e-31 107.8 0.1 7.4e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EEQ35368.1 - 6.5e-18 64.8 0.1 2.9e-11 43.0 0.5 2.1 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EEQ35368.1 - 1.9e-17 63.7 0.1 9.3e-17 61.4 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EEQ35368.1 - 1.6e-14 53.7 0.1 2.3e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EEQ35368.1 - 8.3e-12 44.8 0.1 2.1e-11 43.5 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EEQ35368.1 - 6.4e-08 32.7 0.2 1.7e-07 31.4 0.2 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EEQ35368.1 - 5.5e-07 29.7 0.0 7.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EEQ35368.1 - 0.00023 20.7 0.0 0.00042 19.8 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_3 PF03447.16 EEQ35368.1 - 0.00037 21.1 0.0 0.0014 19.3 0.0 1.9 1 1 1 2 2 2 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EEQ35368.1 - 0.091 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Virul_fac_BrkB PF03631.15 EEQ35369.1 - 0.0053 16.4 4.5 0.0053 16.4 4.5 2.1 2 0 0 2 2 2 1 Virulence factor BrkB PMP1_2 PF08114.11 EEQ35369.1 - 0.012 15.4 3.3 0.035 13.9 3.3 1.7 1 0 0 1 1 1 0 ATPase proteolipid family DUF4064 PF13273.6 EEQ35369.1 - 0.35 11.2 6.5 2.9 8.2 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) p450 PF00067.22 EEQ35370.1 - 4.5e-31 108.1 0.0 1.6e-30 106.2 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Pkinase PF00069.25 EEQ35372.1 - 8.4e-15 54.8 0.0 1.2e-13 51.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35372.1 - 2e-09 37.1 0.0 4.7e-08 32.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ35372.1 - 0.0094 15.3 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ35372.1 - 0.055 13.4 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Phage_glycop_gL PF11108.8 EEQ35372.1 - 0.25 11.4 0.0 0.47 10.5 0.0 1.4 1 0 0 1 1 1 0 Viral glycoprotein L AAA PF00004.29 EEQ35373.1 - 2.8e-15 56.9 0.0 5.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEQ35373.1 - 0.001 19.0 0.0 0.0041 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEQ35373.1 - 0.0012 19.3 0.2 0.0035 17.7 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ35373.1 - 0.0017 18.7 0.6 0.11 12.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 EEQ35373.1 - 0.069 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EEQ35377.1 - 9.9e-95 307.9 12.9 5.3e-12 46.1 0.2 10.4 9 1 1 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ35377.1 - 1.8e-44 150.0 0.0 5.6e-05 23.4 0.0 9.3 1 1 8 9 9 9 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ35377.1 - 5.4e-23 81.5 0.2 0.015 14.3 0.0 7.5 3 2 4 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EEQ35377.1 - 1.9e-20 72.2 7.3 0.17 11.9 0.0 8.6 8 0 0 8 8 8 6 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EEQ35377.1 - 4.5e-19 68.2 0.2 0.00016 20.4 0.0 4.7 2 1 3 5 5 5 4 Cytochrome D1 heme domain VID27 PF08553.10 EEQ35377.1 - 1.7e-18 66.8 0.1 0.0066 15.5 0.0 5.7 2 1 2 6 6 6 4 VID27 C-terminal WD40-like domain TruB_C PF09142.11 EEQ35377.1 - 2.5e-15 56.0 12.3 0.066 13.0 0.0 8.2 5 2 2 8 8 8 3 tRNA Pseudouridine synthase II, C terminal Proteasome_A_N PF10584.9 EEQ35377.1 - 2.4e-14 52.7 2.6 1.9 8.3 0.0 7.7 8 0 0 8 8 7 3 Proteasome subunit A N-terminal signature GSDH PF07995.11 EEQ35377.1 - 1.4e-09 37.8 0.1 4.1 6.6 0.0 7.4 3 2 5 9 9 9 2 Glucose / Sorbosone dehydrogenase Nup160 PF11715.8 EEQ35377.1 - 2.3e-09 36.4 0.4 6.4 5.3 0.0 7.5 3 2 5 8 8 8 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EEQ35377.1 - 3.1e-08 33.5 5.9 5.7e-07 29.4 3.4 2.9 2 1 1 3 3 3 1 PQQ-like domain Nbas_N PF15492.6 EEQ35377.1 - 5.8e-08 32.4 4.0 3.6 6.8 0.0 5.9 1 1 6 7 7 7 4 Neuroblastoma-amplified sequence, N terminal Ret2_MD PF18528.1 EEQ35377.1 - 4.1e-07 30.3 0.1 81 3.7 0.0 7.3 7 1 1 8 8 8 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Ank PF00023.30 EEQ35377.1 - 4.4e-07 30.1 0.0 6.1e-06 26.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EEQ35377.1 - 1.5e-06 28.7 0.0 3.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF2415 PF10313.9 EEQ35377.1 - 1.1e-05 25.3 0.2 21 5.1 0.0 7.0 7 0 0 7 7 7 0 Uncharacterised protein domain (DUF2415) Ank_5 PF13857.6 EEQ35377.1 - 3.5e-05 24.0 0.0 0.00015 22.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ35377.1 - 4.2e-05 23.6 0.0 0.00018 21.7 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat WD40_like PF17005.5 EEQ35377.1 - 5.3e-05 22.7 0.0 0.23 10.8 0.0 3.3 3 0 0 3 3 3 1 WD40-like domain Ank_4 PF13637.6 EEQ35377.1 - 0.00026 21.5 0.0 0.0017 18.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF1652 PF07865.11 EEQ35377.1 - 0.00037 20.3 0.0 1e+02 2.8 0.0 6.4 8 0 0 8 8 8 0 Protein of unknown function (DUF1652) Coatomer_WDAD PF04053.14 EEQ35377.1 - 0.0054 15.8 0.0 2.5 7.1 0.0 3.7 2 1 3 5 5 5 2 Coatomer WD associated region RAB3GAP2_N PF14655.6 EEQ35377.1 - 0.016 14.5 3.2 1.7 7.8 0.0 4.4 2 1 3 5 5 5 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 EEQ35377.1 - 0.047 12.0 0.0 7.9 4.7 0.0 2.9 2 1 1 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF5570 PF17731.1 EEQ35377.1 - 0.052 13.6 12.2 36 4.4 0.0 6.3 2 2 5 7 7 7 0 Family of unknown function (DUF5570) IKI3 PF04762.12 EEQ35377.1 - 0.093 10.7 0.0 7.4 4.4 0.0 3.0 1 1 1 3 3 3 0 IKI3 family DUF4585 PF15232.6 EEQ35377.1 - 0.19 11.8 0.0 56 3.9 0.0 3.8 5 0 0 5 5 3 0 Domain of unknown function (DUF4585) AMP-binding PF00501.28 EEQ35378.1 - 5.4e-75 252.6 0.0 8e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ35378.1 - 1e-11 45.6 0.0 3.3e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_13 PF13880.6 EEQ35380.1 - 5e-28 96.9 0.0 1e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EEQ35380.1 - 5.1e-15 55.0 0.8 9.1e-15 54.2 0.8 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acyl-CoA_dh_1 PF00441.24 EEQ35382.1 - 1.4e-25 90.3 0.5 2.1e-25 89.7 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EEQ35382.1 - 1.4e-24 86.9 0.0 3.1e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EEQ35382.1 - 3e-16 59.4 0.0 5.5e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EEQ35382.1 - 4.6e-08 33.4 1.1 8.1e-08 32.6 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 EEQ35383.1 - 5.2e-52 175.2 0.0 5.8e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ35383.1 - 0.00097 18.8 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EEQ35383.1 - 0.033 14.5 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EEQ35383.1 - 0.068 13.0 0.2 0.13 12.1 0.2 1.4 1 1 0 1 1 1 0 UEV domain Rick_17kDa_Anti PF05433.15 EEQ35384.1 - 0.14 12.1 6.0 0.4 10.6 6.0 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain EMG1 PF03587.14 EEQ35385.1 - 1.4e-65 220.6 0.1 1.4e-64 217.4 0.1 1.9 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase Conotoxin PF02950.17 EEQ35386.1 - 0.0093 17.0 0.6 0.016 16.2 0.6 1.5 1 0 0 1 1 1 1 Conotoxin Toxin_18 PF08087.11 EEQ35386.1 - 0.076 13.0 9.0 0.21 11.6 9.1 1.7 1 1 0 1 1 1 0 Conotoxin O-superfamily Conotoxin_I2 PF17557.2 EEQ35386.1 - 1.3 9.2 9.3 2.5 8.3 9.3 1.6 1 0 0 1 1 1 0 I2-superfamily conotoxins Kdo PF06293.14 EEQ35387.1 - 0.01 15.2 0.3 0.023 14.0 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ35387.1 - 0.017 15.0 0.1 0.017 15.0 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EEQ35387.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain eIF3_subunit PF08597.10 EEQ35387.1 - 0.19 11.6 4.8 0.066 13.1 1.1 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit OmpH PF03938.14 EEQ35387.1 - 9.5 6.6 6.3 40 4.5 6.6 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) XPG_I PF00867.18 EEQ35388.1 - 8.9e-31 106.1 1.2 4.1e-30 104.0 0.0 2.4 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EEQ35388.1 - 1e-26 93.3 0.5 2.2e-26 92.2 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EEQ35388.1 - 0.00012 22.7 0.5 0.00055 20.5 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.11 EEQ35388.1 - 0.02 14.5 2.2 0.044 13.4 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) XRN_N PF03159.18 EEQ35388.1 - 0.066 12.6 0.0 0.066 12.6 0.0 2.3 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Linker_histone PF00538.19 EEQ35389.1 - 1.8e-28 98.7 0.3 1.8e-28 98.7 0.3 2.8 1 1 1 3 3 3 1 linker histone H1 and H5 family Ldi PF18566.1 EEQ35389.1 - 0.23 10.9 2.4 0.28 10.6 2.4 1.2 1 0 0 1 1 1 0 Linalool dehydratase/isomerase SAPS PF04499.15 EEQ35389.1 - 2.7 6.7 9.2 3.3 6.4 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pkinase PF00069.25 EEQ35391.1 - 2.3e-17 63.2 0.0 8.7e-07 28.6 0.0 3.7 2 2 1 3 3 3 3 Protein kinase domain Kinase-like PF14531.6 EEQ35391.1 - 2.4e-06 27.1 0.0 0.033 13.5 0.1 2.5 2 1 1 3 3 3 2 Kinase-like Pkinase_Tyr PF07714.17 EEQ35391.1 - 9.9e-05 21.7 0.1 3.8 6.7 0.0 3.8 3 1 1 4 4 4 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ35391.1 - 0.04 12.7 0.1 0.13 11.0 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EEQ35391.1 - 0.068 13.1 0.2 0.23 11.4 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family PIP5K PF01504.18 EEQ35392.1 - 1.3e-101 339.4 0.0 4e-101 337.9 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.25 EEQ35393.1 - 1e-10 41.4 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EEQ35393.1 - 1.5e-06 28.3 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ35393.1 - 7.9e-06 25.4 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EEQ35393.1 - 3.1e-05 23.4 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EEQ35393.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EEQ35393.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EEQ35394.1 - 7.5e-09 35.9 0.0 2.2e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ35394.1 - 0.00084 19.0 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RRM PF10378.9 EEQ35394.1 - 0.12 12.1 0.3 0.24 11.1 0.3 1.5 1 0 0 1 1 1 0 Putative RRM domain Pox_A_type_inc PF04508.12 EEQ35396.1 - 0.5 10.3 4.0 3.2 7.7 1.5 2.4 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat PDDEXK_7 PF04411.12 EEQ35397.1 - 0.047 13.7 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Peptidase_S64 PF08192.11 EEQ35399.1 - 0.0022 16.6 0.0 0.0031 16.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.13 EEQ35399.1 - 0.073 12.2 0.2 0.72 9.0 0.1 2.0 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 HGTP_anticodon2 PF12745.7 EEQ35400.1 - 0.08 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Asp_protease_2 PF13650.6 EEQ35400.1 - 0.11 13.2 0.0 0.24 12.1 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease Spc7 PF08317.11 EEQ35401.1 - 0.44 9.4 5.4 0.77 8.6 5.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 EEQ35401.1 - 0.49 10.3 3.1 0.47 10.4 1.1 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Seryl_tRNA_N PF02403.22 EEQ35401.1 - 0.8 10.0 3.7 1.2 9.4 2.5 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1589 PF07628.11 EEQ35402.1 - 0.034 14.3 0.2 0.071 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1589) ANAPC1 PF12859.7 EEQ35403.1 - 2.6e-32 112.1 0.9 2.6e-32 112.1 0.9 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EEQ35403.1 - 0.0019 18.5 9.4 0.011 16.1 0.1 4.4 4 0 0 4 4 4 2 Proteasome/cyclosome repeat Fungal_trans_2 PF11951.8 EEQ35404.1 - 5.5e-17 61.7 0.0 1.4e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EEQ35405.1 - 8.7e-27 94.0 26.3 8.7e-27 94.0 26.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily HUN PF08729.10 EEQ35406.1 - 4.8e-08 32.9 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.10 EEQ35407.1 - 3.6e-24 84.6 0.0 6.5e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EEQ35407.1 - 3.6e-15 55.5 6.0 6.2e-15 54.7 6.0 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal ABC2_membrane PF01061.24 EEQ35408.1 - 8.2e-51 172.4 43.9 3.3e-39 134.5 23.5 4.0 4 0 0 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.27 EEQ35408.1 - 1e-39 136.2 0.1 1.5e-18 67.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EEQ35408.1 - 6.1e-34 115.8 0.0 4.1e-26 90.7 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EEQ35408.1 - 1.9e-15 57.2 0.0 5.3e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 EEQ35408.1 - 6.9e-07 29.0 0.1 9.1e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EEQ35408.1 - 2e-06 28.1 0.1 0.011 15.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EEQ35408.1 - 4.5e-06 26.3 0.2 0.0029 17.3 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 EEQ35408.1 - 1.2e-05 24.9 0.0 0.37 10.2 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEQ35408.1 - 1.2e-05 25.3 0.1 0.24 11.2 0.1 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EEQ35408.1 - 2.8e-05 24.6 0.2 0.001 19.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ35408.1 - 0.00017 21.5 0.1 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EEQ35408.1 - 0.00023 21.7 0.0 0.0035 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EEQ35408.1 - 0.00098 19.7 0.0 0.039 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EEQ35408.1 - 0.0029 17.7 0.1 3.5 7.7 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 EEQ35408.1 - 0.0043 17.0 0.8 0.63 9.9 0.2 2.6 2 0 0 2 2 2 1 NACHT domain PDR_assoc PF08370.11 EEQ35408.1 - 0.005 16.5 3.9 0.19 11.5 0.0 2.9 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_22 PF13401.6 EEQ35408.1 - 0.0087 16.3 0.8 0.33 11.2 0.2 2.8 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 EEQ35408.1 - 0.011 15.4 0.6 0.064 12.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EEQ35408.1 - 0.022 15.2 0.1 4.6 7.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EEQ35408.1 - 0.022 14.5 0.1 0.62 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EEQ35408.1 - 0.051 14.0 0.5 0.82 10.1 0.0 2.9 4 0 0 4 4 2 0 AAA domain AAA_28 PF13521.6 EEQ35408.1 - 0.15 12.3 0.6 0.43 10.8 0.6 1.7 1 0 0 1 1 1 0 AAA domain APH PF01636.23 EEQ35409.1 - 3e-13 50.2 0.0 2.1e-12 47.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ35409.1 - 0.00019 21.1 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ35409.1 - 0.07 12.5 0.0 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35409.1 - 0.094 12.0 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase DUF4812 PF16071.5 EEQ35409.1 - 0.23 11.3 1.1 0.53 10.1 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4812) FAD_binding_3 PF01494.19 EEQ35410.1 - 4e-15 55.9 0.1 4.4e-14 52.5 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EEQ35410.1 - 1.4e-06 28.1 0.3 0.00015 21.5 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ35410.1 - 8.8e-06 25.1 0.0 0.0081 15.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EEQ35410.1 - 1e-05 24.6 0.0 0.0012 17.8 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EEQ35410.1 - 2.5e-05 24.4 0.1 5.6e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EEQ35410.1 - 0.00045 19.6 0.1 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EEQ35410.1 - 0.00092 19.2 0.0 0.053 13.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding TetR_C_12 PF16914.5 EEQ35410.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor C-terminal SE PF08491.10 EEQ35410.1 - 0.058 12.4 0.0 8.1 5.4 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 EEQ35410.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EEQ35410.1 - 0.15 12.6 0.1 0.56 10.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEQ35410.1 - 0.22 10.6 1.4 0.36 9.9 1.4 1.3 1 0 0 1 1 1 0 FAD binding domain Methyltransf_23 PF13489.6 EEQ35411.1 - 5.5e-11 42.6 0.0 1.5e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ35411.1 - 9.3e-05 22.3 0.0 0.03 14.1 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ35411.1 - 0.0015 19.2 0.1 1.9 9.3 0.1 2.5 1 1 1 2 2 2 2 Methyltransferase domain DUF938 PF06080.12 EEQ35411.1 - 0.08 12.7 0.0 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_11 PF08241.12 EEQ35411.1 - 0.12 13.0 0.0 8.6 7.1 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain IFRD PF05004.13 EEQ35412.1 - 2.3e-83 279.8 10.6 3e-83 279.4 10.6 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) VHS PF00790.19 EEQ35412.1 - 0.071 13.0 0.1 0.51 10.2 0.0 2.3 2 1 0 2 2 2 0 VHS domain ORC6 PF05460.13 EEQ35412.1 - 4.9 6.3 10.4 0.22 10.7 3.5 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Pkinase PF00069.25 EEQ35413.1 - 1.5e-62 211.3 0.0 1.8e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35413.1 - 5.8e-35 120.8 0.0 8e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ35413.1 - 6e-05 22.0 0.0 9e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEQ35413.1 - 0.037 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 EEQ35413.1 - 0.076 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EEQ35413.1 - 0.081 11.8 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EEQ35413.1 - 0.099 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SH2_2 PF14633.6 EEQ35414.1 - 7.9e-87 290.2 0.0 6.8e-86 287.1 0.0 2.6 3 0 0 3 3 3 1 SH2 domain HTH_44 PF14641.6 EEQ35414.1 - 4.6e-38 130.2 5.9 1.9e-36 125.0 0.5 2.8 2 0 0 2 2 2 2 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 EEQ35414.1 - 1.2e-31 109.5 0.0 3.7e-31 107.9 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 EEQ35414.1 - 5.2e-31 107.1 0.0 1.1e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 EEQ35414.1 - 3e-18 66.2 21.7 3e-18 66.2 21.7 5.9 6 1 1 7 7 7 1 Acidic N-terminal SPT6 HHH_3 PF12836.7 EEQ35414.1 - 8.5e-06 25.9 0.0 3.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif SH2 PF00017.24 EEQ35414.1 - 5.9e-05 23.1 0.0 0.00026 21.1 0.0 2.2 2 0 0 2 2 2 1 SH2 domain HHH_9 PF17674.1 EEQ35414.1 - 0.00017 22.4 3.2 0.00017 22.4 3.2 4.1 2 2 1 3 3 3 1 HHH domain DUF445 PF04286.12 EEQ35414.1 - 0.03 14.1 4.5 1.7 8.4 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF445) Tex_N PF09371.10 EEQ35414.1 - 0.43 10.2 0.0 0.43 10.2 0.0 4.0 4 0 0 4 4 4 0 Tex-like protein N-terminal domain zf-CCCH PF00642.24 EEQ35416.1 - 2.3e-12 46.5 9.3 5.3e-07 29.4 1.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ35416.1 - 2.5e-10 40.0 16.4 3e-06 27.1 1.8 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EEQ35416.1 - 3.4e-10 39.5 9.6 1.7e-06 27.7 2.2 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 EEQ35416.1 - 1.6e-07 32.0 4.0 0.00025 21.7 0.2 3.2 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 EEQ35416.1 - 3.8e-05 23.8 0.1 7.2e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EEQ35416.1 - 0.0015 19.0 14.3 0.093 13.2 3.3 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger SUIM_assoc PF16619.5 EEQ35416.1 - 0.0087 16.1 3.1 0.0087 16.1 3.1 2.7 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 TBPIP PF07106.13 EEQ35417.1 - 1.3e-07 31.4 0.1 3.5e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain BLOC1_2 PF10046.9 EEQ35417.1 - 0.094 13.0 2.0 0.23 11.8 1.9 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 EEQ35417.1 - 0.25 11.8 4.2 0.22 12.0 0.8 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sel1 PF08238.12 EEQ35418.1 - 4.6e-15 55.7 21.9 9.5e-06 26.1 0.4 6.9 7 1 0 7 7 7 4 Sel1 repeat TPR_1 PF00515.28 EEQ35418.1 - 0.016 15.0 2.5 0.069 13.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AbfB PF05270.13 EEQ35418.1 - 0.12 12.4 1.5 3.3 7.7 0.0 2.5 3 0 0 3 3 3 0 Alpha-L-arabinofuranosidase B (ABFB) domain TPR_2 PF07719.17 EEQ35418.1 - 0.83 9.9 4.1 4.5 7.6 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.6 EEQ35419.1 - 6.5e-55 185.9 0.0 1.2e-54 185.0 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EEQ35419.1 - 2.2e-44 151.2 0.0 4.1e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 AAA_22 PF13401.6 EEQ35419.1 - 0.028 14.7 0.2 0.21 11.9 0.2 2.6 3 1 0 3 3 3 0 AAA domain HBB PF06777.11 EEQ35419.1 - 0.028 14.1 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Helical and beta-bridge domain Ribosomal_L27A PF00828.19 EEQ35420.1 - 4.5e-22 79.1 0.0 6.4e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CP2 PF04516.15 EEQ35421.1 - 0.069 12.4 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 CP2 transcription factor PLDc PF00614.22 EEQ35422.1 - 1.6e-16 59.7 0.3 1.7e-07 31.1 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EEQ35422.1 - 2.3e-13 50.2 0.0 2.7e-07 30.5 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 EEQ35422.1 - 1.6e-09 37.8 1.2 4.5e-09 36.3 0.4 2.2 2 0 0 2 2 2 1 PX domain AA_permease PF00324.21 EEQ35423.1 - 5.4e-61 206.6 23.8 2.8e-60 204.3 23.8 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ35423.1 - 4.3e-25 88.4 20.4 6.7e-25 87.8 20.4 1.3 1 0 0 1 1 1 1 Amino acid permease MtN3_slv PF03083.16 EEQ35423.1 - 2.4 8.2 8.0 2.1 8.4 0.2 3.8 4 0 0 4 4 4 0 Sugar efflux transporter for intercellular exchange Methyltransf_31 PF13847.6 EEQ35426.1 - 3e-24 85.5 0.0 4.8e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ35426.1 - 6.5e-16 58.8 0.1 1.5e-15 57.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ35426.1 - 3.4e-13 50.1 0.1 1.2e-12 48.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ35426.1 - 2.2e-12 46.8 0.1 3.3e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EEQ35426.1 - 6e-08 32.7 0.0 1.1e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EEQ35426.1 - 3e-06 27.2 0.1 5.6e-06 26.3 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EEQ35426.1 - 2.8e-05 24.8 0.1 5.5e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEQ35426.1 - 5e-05 22.8 0.6 7.8e-05 22.2 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 EEQ35426.1 - 0.015 14.9 0.6 0.03 13.9 0.6 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 CMAS PF02353.20 EEQ35426.1 - 0.019 14.3 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 EEQ35426.1 - 0.024 14.2 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 EEQ35426.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Tmemb_cc2 PF10267.9 EEQ35427.1 - 0.0063 15.7 0.0 0.007 15.6 0.0 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein bZIP_1 PF00170.21 EEQ35427.1 - 0.012 15.7 3.8 0.017 15.2 3.2 1.6 1 1 1 2 2 2 0 bZIP transcription factor Snf7 PF03357.21 EEQ35427.1 - 0.14 11.7 0.9 0.21 11.2 0.9 1.2 1 0 0 1 1 1 0 Snf7 bZIP_2 PF07716.15 EEQ35427.1 - 1.2 9.3 9.9 0.34 11.0 6.2 2.0 2 1 0 2 2 2 0 Basic region leucine zipper Peptidase_S41 PF03572.18 EEQ35428.1 - 1.3e-08 34.6 0.0 2.8e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 Ras PF00071.22 EEQ35429.1 - 3.7e-26 91.7 0.0 1.6e-12 47.3 0.1 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EEQ35429.1 - 0.0069 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Zn_clus PF00172.18 EEQ35430.1 - 5.3e-07 29.7 14.4 9.1e-07 28.9 14.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.14 EEQ35430.1 - 0.32 9.2 7.2 0.44 8.8 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Aldose_epim PF01263.20 EEQ35431.1 - 2.1e-48 165.1 0.0 1.1e-47 162.8 0.0 1.8 1 1 0 1 1 1 1 Aldose 1-epimerase Glyoxalase_6 PF18029.1 EEQ35432.1 - 3.2e-05 24.7 0.0 4.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain QRPTase_C PF01729.19 EEQ35433.1 - 1.9e-45 154.7 0.7 5.8e-25 88.0 0.1 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EEQ35433.1 - 6.2e-15 55.0 0.0 2e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain LysR_substrate PF03466.20 EEQ35433.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 LysR substrate binding domain Mto2_bdg PF12808.7 EEQ35434.1 - 1.1e-35 121.6 33.1 1.6e-19 69.9 20.1 10.1 11 2 2 13 13 13 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Cnn_1N PF07989.11 EEQ35434.1 - 3.8e-22 78.2 9.1 3.8e-22 78.2 9.1 11.5 7 3 5 12 12 12 2 Centrosomin N-terminal motif 1 Fib_alpha PF08702.10 EEQ35434.1 - 0.0062 16.7 7.0 0.0062 16.7 7.0 7.8 4 1 4 8 8 8 3 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 EEQ35434.1 - 0.44 10.8 0.0 0.44 10.8 0.0 10.1 5 2 4 9 9 9 0 Domain of unknown function (DUF5082) PH_9 PF15410.6 EEQ35435.1 - 1.7e-19 70.3 0.1 7e-19 68.3 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Sec7 PF01369.20 EEQ35435.1 - 0.0038 16.9 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 Sec7 domain UNC-50 PF05216.13 EEQ35437.1 - 1.6e-32 112.9 0.8 1.6e-32 112.9 0.8 1.9 2 1 0 2 2 2 1 UNC-50 family FAD_binding_3 PF01494.19 EEQ35439.1 - 1.1e-11 44.6 0.0 1.6e-10 40.7 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EEQ35439.1 - 2.7e-07 30.1 0.0 0.0043 16.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ35439.1 - 2e-06 28.0 0.0 3.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ35439.1 - 2.5e-06 27.9 0.0 0.00022 21.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ35439.1 - 0.00061 19.5 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase PQQ PF01011.21 EEQ35439.1 - 0.0032 17.3 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 PQQ enzyme repeat TrkA_N PF02254.18 EEQ35439.1 - 0.08 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 EEQ35439.1 - 0.19 10.8 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EEQ35439.1 - 0.21 10.8 0.0 0.89 8.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PetG PF02529.15 EEQ35440.1 - 0.13 12.2 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 MFS_1 PF07690.16 EEQ35441.1 - 3.6e-34 118.2 27.0 2.6e-33 115.4 28.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EEQ35441.1 - 0.00083 18.7 2.7 0.00083 18.7 2.7 2.5 1 1 2 3 3 3 2 Uncharacterised MFS-type transporter YbfB Holin_BhlA PF10960.8 EEQ35441.1 - 0.017 15.1 0.2 0.047 13.7 0.0 1.8 2 0 0 2 2 2 0 BhlA holin family Neurensin PF14927.6 EEQ35441.1 - 0.18 11.5 1.6 0.62 9.8 0.9 2.3 2 0 0 2 2 2 0 Neurensin LapA_dom PF06305.11 EEQ35441.1 - 0.99 9.3 0.0 0.99 9.3 0.0 4.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain YqzM PF14141.6 EEQ35441.1 - 4.3 7.5 5.5 3 8.0 0.1 3.1 3 0 0 3 3 3 0 YqzM-like protein PP28 PF10252.9 EEQ35442.1 - 8.4e-30 103.1 15.4 8.4e-30 103.1 15.4 3.6 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 MFS_1 PF07690.16 EEQ35443.1 - 9.6e-20 70.8 45.8 9.6e-20 70.8 45.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EEQ35444.1 - 2.2e-27 96.1 0.0 1.1e-17 64.3 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35444.1 - 1.4e-09 37.6 0.0 5.5e-07 29.1 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase NACHT PF05729.12 EEQ35445.1 - 0.14 12.1 0.1 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Cupredoxin_1 PF13473.6 EEQ35447.1 - 0.15 12.1 0.0 0.62 10.2 0.0 1.9 2 0 0 2 2 2 0 Cupredoxin-like domain Acetyltransf_7 PF13508.7 EEQ35448.1 - 1.7e-05 25.1 0.0 7.6e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ35448.1 - 0.0005 20.3 0.0 0.0062 16.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ35448.1 - 0.033 14.1 0.0 0.34 10.8 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ35448.1 - 0.095 12.7 0.1 19 5.3 0.0 2.4 1 1 1 2 2 2 0 FR47-like protein Glyco_transf_20 PF00982.21 EEQ35449.1 - 4.6e-149 497.1 0.0 1.3e-148 495.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EEQ35449.1 - 3.3e-80 268.6 0.0 8.4e-80 267.2 0.0 1.7 1 0 0 1 1 1 1 Trehalose-phosphatase APH PF01636.23 EEQ35450.1 - 2.4e-14 53.8 0.0 4.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ35450.1 - 2e-06 27.5 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ35450.1 - 0.00036 20.0 0.0 0.6 9.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 EEQ35450.1 - 0.00072 19.0 0.1 0.0026 17.2 0.0 1.9 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EEQ35450.1 - 0.16 11.3 0.1 0.54 9.5 0.1 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase PAP_assoc PF03828.19 EEQ35451.1 - 0.048 13.9 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Cid1 family poly A polymerase LETM1 PF07766.13 EEQ35452.1 - 8.4e-10 38.4 0.7 8.6e-06 25.3 0.1 2.3 1 1 0 2 2 2 2 LETM1-like protein PAP1 PF08601.10 EEQ35452.1 - 1.3 8.7 6.5 1.6 8.4 6.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 N_BRCA1_IG PF16158.5 EEQ35453.1 - 1.5e-34 118.8 0.0 3.2e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EEQ35453.1 - 8.9e-16 57.4 40.5 2.4e-06 27.3 8.0 3.4 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_2 PF03107.16 EEQ35453.1 - 0.2 12.0 38.1 1.2 9.5 7.1 3.7 3 0 0 3 3 3 0 C1 domain Btz PF09405.10 EEQ35454.1 - 1.2e-17 64.4 0.4 1.2e-17 64.4 0.4 2.2 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.22 EEQ35456.1 - 1e-23 82.9 0.1 2.4e-14 52.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ35456.1 - 0.00012 22.1 0.0 0.028 14.5 0.0 2.9 2 0 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 EEQ35456.1 - 0.023 14.5 0.6 1.3 8.8 0.0 2.6 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain CDC45 PF02724.14 EEQ35456.1 - 8.1 4.6 13.2 2.2 6.5 8.4 1.9 2 0 0 2 2 2 0 CDC45-like protein Ino80_Iec3 PF14612.6 EEQ35457.1 - 5.7e-72 243.2 0.4 8.8e-72 242.6 0.4 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling IF2_N PF04760.15 EEQ35457.1 - 0.08 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region FAD_binding_4 PF01565.23 EEQ35458.1 - 1.4e-19 70.2 0.4 2.6e-19 69.3 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EEQ35458.1 - 2e-08 34.2 1.1 3.8e-08 33.3 0.1 2.0 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.16 EEQ35459.1 - 8.6e-07 28.2 14.0 8.6e-07 28.2 14.0 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Dynamin_N PF00350.23 EEQ35460.1 - 4.7e-36 124.4 0.1 9.7e-36 123.4 0.1 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EEQ35460.1 - 1.5e-23 83.5 0.3 1.9e-22 79.8 0.3 2.2 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EEQ35460.1 - 7.3e-06 26.0 0.0 2.6e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ35460.1 - 0.049 14.0 0.5 0.56 10.6 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 EEQ35460.1 - 0.057 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EEQ35460.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EEQ35460.1 - 0.17 12.1 0.0 0.81 9.9 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ECR1_N PF14382.6 EEQ35461.1 - 9.2e-15 54.2 0.4 2.2e-14 52.9 0.4 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EEQ35461.1 - 1.4e-05 25.4 0.2 2.7e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EEQ35461.1 - 0.031 14.9 1.3 0.68 10.6 0.1 2.8 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 Oxysterol_BP PF01237.18 EEQ35462.1 - 2.5e-120 401.8 0.0 5.6e-120 400.6 0.0 1.6 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EEQ35462.1 - 5.6e-38 129.1 1.1 8.6e-38 128.5 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EEQ35462.1 - 4.5e-05 23.9 0.7 0.00025 21.5 0.0 2.3 2 0 0 2 2 2 1 PH domain HGAL PF15666.5 EEQ35462.1 - 0.15 12.2 0.5 0.56 10.3 0.1 2.2 2 0 0 2 2 2 0 Germinal center-associated lymphoma CCDC50_N PF15295.6 EEQ35462.1 - 4.5 7.5 10.7 6.5 6.9 0.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus Plus-3 PF03126.18 EEQ35463.1 - 3.8e-30 104.6 0.0 1.6e-28 99.4 0.0 2.7 3 0 0 3 3 3 1 Plus-3 domain DUF4440 PF14534.6 EEQ35463.1 - 0.069 13.6 0.4 0.17 12.3 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) COQ7 PF03232.13 EEQ35464.1 - 5.7e-67 224.8 0.4 7.8e-67 224.3 0.4 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EEQ35464.1 - 0.0022 18.4 0.1 0.0072 16.7 0.0 1.9 2 1 0 2 2 2 1 Rubrerythrin Crr6 PF08847.11 EEQ35464.1 - 0.084 12.5 0.1 1.7 8.3 0.0 2.1 1 1 1 2 2 2 0 Chlororespiratory reduction 6 DUF4611 PF15387.6 EEQ35464.1 - 0.1 12.8 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) LMWPc PF01451.21 EEQ35465.1 - 7.8e-40 136.5 0.0 8.7e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.17 EEQ35466.1 - 8.3e-74 247.0 0.0 1.3e-73 246.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EEQ35466.1 - 6.2e-29 99.8 0.0 1.1e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EEQ35466.1 - 6.4e-21 74.6 1.4 6.3e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EEQ35466.1 - 1.7e-06 28.1 8.2 1.7e-06 28.1 8.2 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF4199 PF13858.6 EEQ35466.1 - 0.23 11.8 13.6 0.92 9.9 13.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CbtA PF09490.10 EEQ35466.1 - 2.2 8.0 7.1 12 5.6 0.1 2.5 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Lipase_GDSL_2 PF13472.6 EEQ35467.1 - 3.5e-12 47.1 0.1 4.2e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EEQ35467.1 - 3.5e-06 27.1 0.0 5.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TMEM234 PF10639.9 EEQ35468.1 - 3.2e-33 114.2 1.8 2.5e-32 111.3 1.8 2.0 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EEQ35468.1 - 0.0026 17.9 9.3 0.048 13.8 5.0 2.4 2 0 0 2 2 2 2 EamA-like transporter family Pkinase_Tyr PF07714.17 EEQ35469.1 - 7.5e-06 25.4 0.0 0.076 12.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ35470.1 - 6.3e-107 357.9 0.1 3.6e-103 345.5 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EEQ35470.1 - 5.5e-08 32.5 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35470.1 - 0.0042 16.4 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EEQ35470.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EEQ35470.1 - 0.16 11.9 0.1 0.85 9.5 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family UBA2_C PF16195.5 EEQ35470.1 - 0.4 11.4 3.6 0.96 10.2 3.6 1.6 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus MFS_MOT1 PF16983.5 EEQ35471.1 - 1.3e-60 202.7 35.3 1.7e-32 112.1 10.4 3.0 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily DUF2755 PF10954.8 EEQ35471.1 - 2.5 8.1 0.0 2.5 8.1 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2755) PhyH PF05721.13 EEQ35473.1 - 9e-45 153.5 0.0 1.2e-44 153.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EEQ35473.1 - 0.025 15.0 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase UTP15_C PF09384.10 EEQ35474.1 - 1.8e-51 173.7 0.7 3.9e-51 172.6 0.1 1.8 1 1 1 2 2 2 1 UTP15 C terminal WD40 PF00400.32 EEQ35474.1 - 2.5e-17 62.9 4.4 0.00042 21.1 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ35474.1 - 4.7e-08 33.2 0.2 0.037 14.3 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EEQ35474.1 - 0.00051 19.7 1.5 0.0042 16.7 0.2 2.5 1 1 1 2 2 2 1 PQQ-like domain RAB3GAP2_N PF14655.6 EEQ35474.1 - 0.015 14.5 0.1 4.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 EEQ35474.1 - 0.017 13.8 0.5 4.1 5.9 0.1 3.3 2 1 2 4 4 4 0 Nucleoporin Nup120/160 C2 PF00168.30 EEQ35475.1 - 3.9e-15 56.0 0.0 7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain AAA_12 PF13087.6 EEQ35476.1 - 9.3e-29 100.5 0.0 1.6e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEQ35476.1 - 8e-18 65.2 1.4 5.1e-12 46.1 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 EEQ35476.1 - 1.5e-08 35.1 0.0 2.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EEQ35476.1 - 0.00031 20.4 0.0 0.001 18.7 0.0 1.8 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 EEQ35476.1 - 0.00042 20.1 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EEQ35476.1 - 0.0096 15.7 0.0 0.68 9.6 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EEQ35476.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C PF13361.6 EEQ35476.1 - 0.053 12.9 0.0 0.96 8.7 0.0 2.8 3 1 1 4 4 4 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EEQ35476.1 - 0.062 12.5 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Fungal_trans PF04082.18 EEQ35477.1 - 7.3e-11 41.6 0.4 1e-10 41.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ35477.1 - 2.1e-10 40.5 10.4 3.7e-10 39.8 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FANCL_C PF11793.8 EEQ35478.1 - 0.0082 16.3 2.5 0.0082 16.3 2.5 2.5 3 0 0 3 3 3 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EEQ35478.1 - 0.0086 16.4 5.5 0.0086 16.4 5.5 3.7 5 0 0 5 5 5 1 Ring finger domain zf-Di19 PF05605.12 EEQ35478.1 - 0.029 14.7 3.3 1.8 9.0 0.2 3.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 EEQ35478.1 - 1.4 9.3 8.3 7.8 6.9 0.0 4.0 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 EEQ35478.1 - 2.8 8.0 9.1 0.47 10.4 0.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type OTU PF02338.19 EEQ35480.1 - 2.9e-07 31.0 0.0 7.5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 EEQ35480.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Bromodomain PF00439.25 EEQ35481.1 - 3.5e-36 123.1 4.7 4.3e-19 68.4 0.8 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EEQ35481.1 - 2e-16 60.0 0.2 4.7e-16 58.8 0.2 1.7 1 0 0 1 1 1 1 BAH domain HTH_32 PF13565.6 EEQ35481.1 - 0.082 13.5 3.2 0.64 10.7 0.1 3.4 2 1 1 3 3 3 0 Homeodomain-like domain CDC45 PF02724.14 EEQ35481.1 - 1.8 6.8 14.2 0.05 11.9 5.7 2.0 2 0 0 2 2 2 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EEQ35481.1 - 3.7 8.0 9.2 2.2 8.7 0.3 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 EEQ35481.1 - 6.6 4.7 8.7 10 4.1 8.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi MRC1 PF09444.10 EEQ35482.1 - 1.8e-41 142.1 21.4 1.8e-41 142.1 21.4 6.8 6 2 2 8 8 8 1 MRC1-like domain Cwf_Cwc_15 PF04889.12 EEQ35483.1 - 0.0054 16.5 0.9 0.0089 15.8 0.9 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Hydrolase_like PF13242.6 EEQ35484.1 - 2.4e-05 24.3 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PheRS_DBD1 PF18552.1 EEQ35484.1 - 0.0092 15.7 0.1 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 1 HAD_2 PF13419.6 EEQ35484.1 - 0.011 15.8 0.0 0.11 12.6 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ35484.1 - 0.028 14.7 0.0 1 9.6 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase MIF4G PF02854.19 EEQ35485.1 - 1.4e-23 83.7 2.5 1.8e-22 80.0 2.0 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 EEQ35485.1 - 1.3e-18 67.0 0.0 3.7e-18 65.5 0.0 1.9 1 0 0 1 1 1 1 MA3 domain SRP14 PF02290.15 EEQ35486.1 - 6.9e-27 93.6 0.0 1e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Inp1 PF12634.7 EEQ35487.1 - 3.6e-28 98.3 0.0 3.6e-27 95.0 0.0 2.3 1 1 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.11 EEQ35488.1 - 3.3e-08 34.0 7.3 4.1e-06 27.2 7.2 2.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Sugar_tr PF00083.24 EEQ35490.1 - 5.4e-39 134.3 22.7 7.7e-25 87.7 6.1 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 EEQ35490.1 - 5.6e-22 78.1 21.6 2.1e-19 69.7 20.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily NADH-u_ox-rdase PF10785.9 EEQ35490.1 - 0.18 12.5 4.4 0.23 12.1 0.2 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit S36_mt PF10937.8 EEQ35490.1 - 6.7 8.3 7.4 1.6 10.3 4.0 1.7 2 0 0 2 2 2 0 Ribosomal protein S36, mitochondrial Helo_like_N PF17111.5 EEQ35491.1 - 0.092 12.1 0.2 0.53 9.6 0.2 2.0 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins MRNIP PF15749.5 EEQ35491.1 - 0.1 13.4 0.0 0.32 11.7 0.0 1.8 1 0 0 1 1 1 0 MRN-interacting protein MazG-like PF12643.7 EEQ35493.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 MazG-like family TNT PF14021.6 EEQ35495.1 - 2.2e-31 108.3 0.0 3.4e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin FmdA_AmdA PF03069.15 EEQ35496.1 - 5.9e-21 74.7 0.1 4.3e-16 58.7 0.1 2.0 2 0 0 2 2 2 2 Acetamidase/Formamidase family Pro_isomerase PF00160.21 EEQ35497.1 - 2.1e-42 145.1 0.2 3.8e-42 144.2 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EEQ35497.1 - 3.8e-05 23.5 10.6 5.6e-05 22.9 3.9 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ35497.1 - 5.5e-05 22.8 2.0 5.5e-05 22.8 2.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ35497.1 - 0.024 14.8 4.7 0.083 13.0 1.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ35497.1 - 0.03 15.1 2.8 0.03 15.1 2.8 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ35497.1 - 0.29 11.8 12.8 0.79 10.4 9.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin_3 PF13192.6 EEQ35497.1 - 0.29 11.2 0.9 3 8.0 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin domain TPR_8 PF13181.6 EEQ35497.1 - 0.42 10.9 11.1 0.11 12.8 2.5 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ35497.1 - 1.5 9.2 7.1 8.2 6.8 5.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ35497.1 - 4.9 7.8 10.9 6.3 7.4 6.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.16 EEQ35498.1 - 1.2e-51 175.1 0.0 1.3e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 EEQ35499.1 - 9.2e-87 290.3 16.7 1.3e-86 289.8 16.7 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EEQ35499.1 - 3.1e-36 124.3 10.2 6.8e-36 123.2 10.2 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 EEQ35499.1 - 0.08 12.8 4.8 0.17 11.7 4.8 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) CLZ PF16526.5 EEQ35499.1 - 0.32 11.4 5.4 0.1 13.0 0.5 2.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin_2 PF14523.6 EEQ35499.1 - 1.7 9.0 11.0 0.057 13.8 2.9 2.7 3 0 0 3 3 3 0 Syntaxin-like protein CENP-Q PF13094.6 EEQ35499.1 - 3.9 7.6 12.6 1.2 9.4 8.8 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-C2H2 PF00096.26 EEQ35500.1 - 9.2e-05 22.7 6.8 0.079 13.5 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EEQ35500.1 - 0.00024 21.3 1.5 0.00045 20.4 1.5 1.4 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EEQ35500.1 - 0.059 14.2 6.5 0.068 14.0 0.2 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger APH PF01636.23 EEQ35501.1 - 3.6e-13 50.0 0.0 1.6e-12 47.9 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Thx PF17070.5 EEQ35501.1 - 0.11 12.6 0.9 0.24 11.6 0.9 1.5 1 0 0 1 1 1 0 30S ribosomal protein Thx Pkinase_fungal PF17667.1 EEQ35502.1 - 1.1e-94 317.6 0.0 2.3e-53 181.5 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase DUF4539 PF15072.6 EEQ35503.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Pkinase PF00069.25 EEQ35504.1 - 8.3e-11 41.7 0.0 1.4e-09 37.7 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35504.1 - 8.6e-06 25.2 0.0 0.00044 19.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ35504.1 - 0.003 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5423 PF17461.2 EEQ35505.1 - 0.088 11.7 1.7 0.1 11.5 1.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5423) DNA_binding_1 PF01035.20 EEQ35506.1 - 5.3e-25 87.3 0.0 8.2e-25 86.7 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Rubella_Capsid PF05750.11 EEQ35506.1 - 0.0042 16.7 0.7 0.0064 16.1 0.0 1.6 2 0 0 2 2 2 1 Rubella capsid protein DUF3439 PF11921.8 EEQ35506.1 - 0.24 11.4 4.7 0.36 10.8 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sugar_tr PF00083.24 EEQ35507.1 - 3.3e-50 171.3 6.7 4.1e-50 171.0 6.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ35507.1 - 1.2e-18 67.2 10.7 1.4e-18 67.0 10.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ35507.1 - 6.7e-05 21.5 3.9 0.0001 20.9 3.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EEQ35507.1 - 0.00014 21.2 6.4 0.00022 20.6 6.4 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Rick_17kDa_Anti PF05433.15 EEQ35507.1 - 0.019 14.8 10.3 0.05 13.5 10.3 1.8 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 EEQ35507.1 - 0.021 14.6 6.2 0.049 13.4 6.2 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper OATP PF03137.20 EEQ35507.1 - 0.12 10.6 4.7 0.089 11.1 0.1 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PT-VENN PF04829.13 EEQ35507.1 - 0.12 12.4 1.2 0.31 11.1 1.2 1.7 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Gly-zipper_Omp PF13488.6 EEQ35507.1 - 4.4 7.4 10.8 0.17 11.9 2.1 2.1 1 1 1 2 2 2 0 Glycine zipper Pyr_redox_dim PF02852.22 EEQ35508.1 - 2.1e-39 134.2 0.1 4.7e-39 133.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.14 EEQ35508.1 - 4.1e-32 111.6 8.8 2.1e-28 99.4 0.1 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ35508.1 - 1.9e-13 50.7 1.5 7.2e-13 48.9 1.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEQ35508.1 - 0.0012 18.0 4.6 0.0015 17.7 3.5 1.7 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EEQ35508.1 - 0.005 16.2 6.1 0.02 14.3 4.1 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EEQ35508.1 - 0.0063 15.3 1.8 0.015 14.1 0.4 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EEQ35508.1 - 0.0063 15.6 3.2 0.011 14.9 3.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EEQ35508.1 - 0.041 13.2 1.7 0.53 9.5 1.2 2.6 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EEQ35508.1 - 0.044 13.4 6.1 3.2 7.2 3.2 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 EEQ35508.1 - 0.048 12.8 0.1 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) THF_DHG_CYH_C PF02882.19 EEQ35508.1 - 0.078 12.3 0.1 0.2 11.0 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Thi4 PF01946.17 EEQ35508.1 - 0.094 11.9 1.0 0.15 11.3 1.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF1106 PF06523.11 EEQ35508.1 - 0.18 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) NAD_binding_8 PF13450.6 EEQ35508.1 - 0.18 12.0 2.0 0.49 10.7 2.0 1.7 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EEQ35508.1 - 0.3 10.3 2.3 1.6 7.9 2.3 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PGM_PMM_I PF02878.16 EEQ35510.1 - 1e-27 96.5 0.0 1.8e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EEQ35510.1 - 3.4e-24 85.4 0.0 8.3e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EEQ35510.1 - 4.1e-16 59.2 0.0 7.8e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EEQ35510.1 - 3e-07 30.5 0.0 8.5e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FA_desaturase PF00487.24 EEQ35511.1 - 4.4e-26 92.3 25.0 6.7e-26 91.7 25.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EEQ35511.1 - 2.4e-11 43.6 0.0 5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PI-TkoII_IV PF18714.1 EEQ35511.1 - 0.092 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV CUE PF02845.16 EEQ35512.1 - 1.6e-10 40.5 0.1 3.6e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.22 EEQ35513.1 - 2.2e-26 91.9 0.4 2.6e-26 91.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH_4 PF18044.1 EEQ35514.1 - 2.6e-07 30.3 2.2 5.6e-07 29.2 2.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EEQ35514.1 - 1.2e-06 28.3 2.9 2.1e-06 27.5 2.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ35514.1 - 5.4e-06 26.3 6.7 1.1e-05 25.3 6.7 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EEQ35514.1 - 0.018 15.7 1.4 0.035 14.8 1.4 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 EEQ35514.1 - 0.039 14.4 2.4 0.086 13.4 2.4 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger ELYS PF13934.6 EEQ35515.1 - 3.5e-66 223.3 0.1 5.4e-66 222.7 0.1 1.3 1 0 0 1 1 1 1 Nuclear pore complex assembly Pox_I3 PF04661.12 EEQ35515.1 - 0.012 14.7 0.0 0.58 9.2 0.0 2.2 2 1 0 2 2 2 0 Poxvirus I3 ssDNA-binding protein SMC_N PF02463.19 EEQ35516.1 - 1.4e-65 220.8 38.3 6.1e-65 218.7 38.3 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEQ35516.1 - 2e-24 86.2 0.1 8.1e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EEQ35516.1 - 2.1e-12 47.5 0.2 4.4e-05 23.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EEQ35516.1 - 6.2e-07 29.5 22.4 6.2e-07 29.5 22.4 4.2 2 2 1 3 3 3 1 AAA ATPase domain Tektin PF03148.14 EEQ35516.1 - 9.8e-05 21.3 12.6 9.8e-05 21.3 12.6 5.2 3 2 1 4 4 4 1 Tektin family AAA_29 PF13555.6 EEQ35516.1 - 0.00059 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 EEQ35516.1 - 0.0044 17.3 16.1 0.0044 17.3 16.1 8.1 4 2 3 7 7 7 2 Autophagy protein 16 (ATG16) Fungal_trans PF04082.18 EEQ35517.1 - 1.5e-12 47.2 0.6 3.1e-12 46.1 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ35517.1 - 4.2e-08 33.2 5.2 8.4e-08 32.2 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.12 EEQ35518.1 - 2.6e-67 226.5 0.0 3e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Ribonuc_L-PSP PF01042.21 EEQ35519.1 - 9.2e-10 38.6 0.0 1.4e-09 38.0 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.32 EEQ35520.1 - 2.3e-05 25.0 7.2 0.067 14.1 0.4 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat RNA_pol_N PF01194.17 EEQ35521.1 - 5.7e-31 106.6 1.4 6.6e-31 106.4 1.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EEQ35521.1 - 0.082 13.2 1.2 0.16 12.2 1.2 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Sugar_tr PF00083.24 EEQ35523.1 - 4.4e-106 355.4 26.4 5.2e-106 355.2 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ35523.1 - 1.3e-23 83.6 39.8 4.5e-15 55.4 12.4 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ35523.1 - 0.0058 15.2 20.6 0.021 13.4 1.3 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2905 PF11146.8 EEQ35523.1 - 2 8.6 7.8 3.9 7.7 2.7 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2905) DIOX_N PF14226.6 EEQ35524.1 - 8.3e-36 123.3 0.0 4.8e-34 117.6 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EEQ35524.1 - 5.4e-15 55.7 0.0 1.5e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 EEQ35524.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain MFS_1 PF07690.16 EEQ35525.1 - 2.1e-37 128.9 46.4 2.1e-37 128.9 46.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2254 PF10011.9 EEQ35525.1 - 0.00041 19.3 0.0 0.00086 18.2 0.0 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) LacY_symp PF01306.19 EEQ35525.1 - 0.00082 18.2 0.9 0.00082 18.2 0.9 2.5 2 1 0 2 2 2 1 LacY proton/sugar symporter Sigma_reg_N PF13800.6 EEQ35525.1 - 0.24 11.7 0.7 1 9.7 0.2 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DNA_primase_S PF01896.19 EEQ35526.1 - 4.2e-63 212.6 0.1 7.9e-63 211.7 0.1 1.4 1 0 0 1 1 1 1 DNA primase small subunit MAM33 PF02330.16 EEQ35527.1 - 3.4e-74 249.4 0.4 4e-74 249.1 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tma16 PF11176.8 EEQ35529.1 - 4.4e-49 166.1 3.3 5.6e-49 165.8 3.3 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 NlpE_C PF17185.4 EEQ35529.1 - 0.033 14.5 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 NlpE C-terminal OB domain XPG_I PF00867.18 EEQ35530.1 - 5.4e-22 78.0 0.0 1e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EEQ35530.1 - 2.7e-21 75.9 0.0 2.9e-20 72.6 0.0 2.4 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 EEQ35530.1 - 0.0055 16.2 0.0 0.0096 15.4 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 EEQ35530.1 - 0.041 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ35530.1 - 0.073 13.9 0.1 0.21 12.5 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Fig1 PF12351.8 EEQ35532.1 - 2e-58 197.4 3.9 2e-58 197.4 3.9 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EEQ35532.1 - 7.5e-06 25.7 8.9 1.3e-05 24.9 8.9 1.4 1 1 0 1 1 1 1 SUR7/PalI family MLTD_N PF06474.12 EEQ35532.1 - 6.4 7.0 7.1 2.6 8.3 3.0 2.3 2 0 0 2 2 2 0 MltD lipid attachment motif DUF898 PF05987.13 EEQ35532.1 - 7.4 5.5 11.3 0.55 9.2 5.9 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) HAD_SAK_1 PF10307.9 EEQ35533.1 - 1.2e-75 253.8 0.0 5.9e-75 251.5 0.0 1.8 2 0 0 2 2 2 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins zf-RING_2 PF13639.6 EEQ35534.1 - 8.8e-09 35.6 3.7 1.5e-08 34.8 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EEQ35534.1 - 3.2e-07 30.1 1.1 5.2e-07 29.4 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ35534.1 - 1.3e-06 28.1 4.6 2.2e-06 27.4 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ35534.1 - 8.2e-06 26.0 2.2 1.8e-05 24.9 2.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EEQ35534.1 - 1.6e-05 24.7 2.9 2.9e-05 23.8 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEQ35534.1 - 0.002 17.9 2.9 0.0037 17.1 2.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EEQ35534.1 - 0.012 15.3 1.1 0.026 14.3 1.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 EEQ35534.1 - 0.21 11.6 1.7 0.36 10.8 1.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Drc1-Sld2 PF11719.8 EEQ35535.1 - 9.8e-79 266.0 16.5 1.1e-78 265.8 16.5 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein MciZ PF13072.6 EEQ35535.1 - 0.036 13.9 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Edc3_linker PF16598.5 EEQ35535.1 - 0.69 10.6 4.9 1.7 9.3 0.4 3.1 2 1 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 2-oxoacid_dh PF00198.23 EEQ35536.1 - 7.1e-53 179.4 0.6 8.7e-52 175.9 0.6 2.3 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EEQ35536.1 - 1.8e-15 56.5 0.8 3.6e-15 55.5 0.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF1854 PF08909.11 EEQ35536.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) FAM76 PF16046.5 EEQ35536.1 - 0.46 9.8 3.6 4.3 6.6 2.4 2.0 2 0 0 2 2 2 0 FAM76 protein Presenilin PF01080.17 EEQ35536.1 - 0.95 8.2 5.0 1.4 7.6 5.0 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 EEQ35536.1 - 1.1 8.0 4.1 1.5 7.4 4.1 1.1 1 0 0 1 1 1 0 Raftlin Ndc1_Nup PF09531.10 EEQ35536.1 - 1.8 7.1 6.4 2.8 6.5 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3275 PF11679.8 EEQ35536.1 - 2.6 8.0 5.4 4.7 7.1 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF2052 PF09747.9 EEQ35536.1 - 9.1 6.3 8.8 14 5.8 8.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Complex1_LYR PF05347.15 EEQ35537.1 - 1.1e-08 34.9 0.3 1.6e-08 34.5 0.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEQ35537.1 - 0.16 12.8 1.1 0.23 12.3 1.1 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Histone PF00125.24 EEQ35538.1 - 3.2e-16 59.9 0.0 4.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EEQ35538.1 - 1.8e-14 53.2 0.0 3.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EEQ35538.1 - 2.8e-05 24.3 0.0 3.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ35539.1 - 6.3e-19 68.6 2.3 8e-19 68.3 2.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEQ35539.1 - 0.00014 22.0 0.1 0.00014 22.0 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EEQ35539.1 - 0.0036 17.8 0.0 0.0059 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Cytochrome-c551 PF10643.9 EEQ35539.1 - 0.12 11.9 0.3 0.17 11.4 0.3 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Peptidase_C54 PF03416.19 EEQ35540.1 - 5e-97 324.6 0.0 7.7e-97 324.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 R3H PF01424.22 EEQ35541.1 - 1.3e-13 50.8 0.0 2.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EEQ35541.1 - 4.6e-09 36.0 0.4 9.3e-09 35.0 0.4 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EEQ35541.1 - 0.039 14.0 0.4 0.039 14.0 0.4 2.3 3 0 0 3 3 3 0 G-patch domain DnaJ PF00226.31 EEQ35542.1 - 8.1e-25 86.7 1.6 3.6e-24 84.7 0.5 2.5 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.7 EEQ35542.1 - 2.2e-11 43.8 7.7 8.5e-09 35.5 2.7 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEQ35542.1 - 1.9e-10 40.7 11.4 8.6e-10 38.7 6.5 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EEQ35542.1 - 1.8e-08 34.6 8.0 0.0009 19.5 2.5 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EEQ35542.1 - 2.3e-07 30.9 7.0 0.0038 17.6 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ35542.1 - 5.9e-06 26.7 7.3 0.015 16.1 0.4 2.9 3 0 0 3 3 2 2 C2H2-type zinc finger Actin_micro PF17003.5 EEQ35542.1 - 7e-05 22.2 1.1 0.0081 15.4 0.1 2.4 2 1 0 2 2 2 2 Putative actin-like family zf-C2H2_3rep PF18868.1 EEQ35542.1 - 0.0044 17.7 4.0 1.2 9.8 0.1 3.3 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 EEQ35542.1 - 0.0094 15.9 9.0 0.88 9.6 2.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.22 EEQ35542.1 - 0.026 14.7 4.0 1.9 8.8 0.7 2.4 2 0 0 2 2 2 0 LIM domain zf-C2H2_12 PF18658.1 EEQ35542.1 - 0.027 14.1 0.3 9.9 5.8 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger C2H2-type DUF2256 PF10013.9 EEQ35542.1 - 0.062 13.4 0.3 9.8 6.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-BED PF02892.15 EEQ35542.1 - 0.084 12.9 0.1 19 5.4 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 EEQ35542.1 - 0.33 11.4 2.1 5 7.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_11 PF17123.5 EEQ35542.1 - 0.39 10.5 1.6 14 5.5 0.4 2.4 2 0 0 2 2 2 0 RING-like zinc finger DUF3449 PF11931.8 EEQ35542.1 - 0.45 10.3 9.3 0.062 13.1 2.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3449) zf-Di19 PF05605.12 EEQ35542.1 - 0.5 10.7 5.0 3 8.2 0.0 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding YccV-like PF08755.11 EEQ35544.1 - 2e-29 102.0 0.3 4.3e-29 100.9 0.3 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 EEQ35544.1 - 1.8e-14 53.6 0.0 3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 EEQ35544.1 - 7e-06 25.8 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ35544.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain SPX PF03105.19 EEQ35545.1 - 4.6e-43 148.6 2.4 3.5e-41 142.4 2.4 2.3 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EEQ35545.1 - 3.5e-07 30.0 9.4 7.9e-07 28.8 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEQ35545.1 - 1.5e-05 25.0 10.9 1.5e-05 25.0 10.9 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EEQ35545.1 - 5.6e-05 22.9 11.9 5.6e-05 22.9 11.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ35545.1 - 0.00014 21.7 10.6 0.00014 21.7 10.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EEQ35545.1 - 0.0003 21.1 12.3 0.0003 21.1 12.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ35545.1 - 0.00052 19.8 12.1 0.00052 19.8 12.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ35545.1 - 0.0007 19.6 10.9 0.0019 18.2 10.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EEQ35545.1 - 0.0053 16.8 3.4 0.013 15.5 2.8 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY_C PF15616.6 EEQ35545.1 - 0.0056 16.8 0.9 0.01 15.9 0.9 1.4 1 0 0 1 1 1 1 TerY-C metal binding domain Prok-RING_4 PF14447.6 EEQ35545.1 - 0.011 15.6 10.2 0.039 13.8 10.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EEQ35545.1 - 0.014 15.2 3.5 0.014 15.2 3.5 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EEQ35545.1 - 0.27 10.9 8.2 7.3 6.3 8.6 2.3 1 1 1 2 2 2 0 P-11 zinc finger zf-rbx1 PF12678.7 EEQ35545.1 - 0.45 10.8 10.4 2.2 8.6 10.4 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain Auto_anti-p27 PF06677.12 EEQ35545.1 - 7.7 6.8 7.3 21 5.3 3.6 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Peptidase_C12 PF01088.21 EEQ35546.1 - 5e-63 212.7 0.0 7.6e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EEQ35546.1 - 2.4e-06 27.3 0.1 6.3e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases I-set PF07679.16 EEQ35547.1 - 0.00017 21.6 0.1 0.03 14.4 0.0 3.9 4 1 0 4 4 4 1 Immunoglobulin I-set domain DUF1918 PF08940.11 EEQ35547.1 - 0.002 17.7 0.0 10 5.8 0.0 4.0 3 0 0 3 3 3 3 Domain of unknown function (DUF1918) Nrap_D5 PF17406.2 EEQ35548.1 - 5.6e-52 175.8 0.5 1.9e-51 174.0 0.1 2.1 3 0 0 3 3 3 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EEQ35548.1 - 5e-51 172.5 0.0 7.3e-48 162.2 0.0 3.4 4 0 0 4 4 4 2 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 EEQ35548.1 - 1.5e-46 158.4 1.8 2.8e-46 157.6 1.8 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 EEQ35548.1 - 1.9e-41 141.6 0.4 3.8e-41 140.7 0.4 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 EEQ35548.1 - 1.4e-40 139.0 0.0 3.8e-40 137.6 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EEQ35548.1 - 1.2e-29 103.2 0.0 3.5e-29 101.7 0.0 1.9 1 0 0 1 1 1 1 Nrap protein domain 6 TetR_C_13 PF16925.5 EEQ35548.1 - 0.17 11.8 0.1 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Cys_Met_Meta_PP PF01053.20 EEQ35549.1 - 3e-33 114.9 0.0 3.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MRP-L20 PF12824.7 EEQ35551.1 - 7.5e-59 198.6 3.9 8.6e-59 198.4 3.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 EEQ35551.1 - 0.031 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Neugrin Peptidase_M20 PF01546.28 EEQ35552.1 - 1.5e-31 109.7 0.0 2.3e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEQ35552.1 - 1.3e-11 44.4 0.0 2.1e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EEQ35552.1 - 0.021 14.5 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 CobS_N PF12556.8 EEQ35552.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal PRELI PF04707.14 EEQ35553.1 - 2.7e-25 89.0 0.1 6.5e-22 78.0 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family His_Phos_1 PF00300.22 EEQ35554.1 - 2.2e-23 82.9 0.0 3e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 EEQ35555.1 - 7.9e-74 248.3 0.0 1.1e-73 247.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35555.1 - 3.8e-37 128.0 0.0 5.2e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EEQ35555.1 - 9.1e-19 68.0 0.0 9.1e-11 42.2 0.0 2.8 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EEQ35555.1 - 4.4e-15 55.5 0.0 9.9e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EEQ35555.1 - 2e-06 27.3 0.0 3.7e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EEQ35555.1 - 0.00019 21.1 0.2 0.00037 20.1 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EEQ35555.1 - 0.00089 18.3 0.2 0.002 17.1 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 EEQ35555.1 - 0.01 14.7 0.1 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 EEQ35555.1 - 0.026 14.5 1.8 0.059 13.3 0.1 2.3 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 EEQ35555.1 - 0.13 11.6 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EEQ35555.1 - 0.14 11.2 0.5 0.22 10.6 0.5 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MARVEL PF01284.23 EEQ35556.1 - 3.4e-24 85.5 10.4 4.2e-24 85.2 10.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain PPP4R2 PF09184.11 EEQ35558.1 - 3.4 7.2 18.9 1.9 8.0 17.5 1.3 1 1 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 EEQ35558.1 - 3.6 5.7 27.8 4.7 5.3 27.8 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EEQ35558.1 - 4.2 5.4 31.7 0.11 10.6 20.1 2.0 2 0 0 2 2 2 0 DNA polymerase phi His_Phos_1 PF00300.22 EEQ35560.1 - 1.8e-10 40.8 0.0 8.1e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M28 PF04389.17 EEQ35561.1 - 2.7e-29 102.3 0.1 5.4e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EEQ35561.1 - 0.00023 20.9 0.1 0.00045 20.0 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SoxG PF04268.12 EEQ35561.1 - 0.014 15.6 0.1 0.21 11.8 0.1 2.3 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family DUF4317 PF14199.6 EEQ35561.1 - 0.037 13.2 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) Phage_holin_3_6 PF07332.11 EEQ35562.1 - 8.5 6.5 10.9 0.67 10.0 5.2 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RRM_1 PF00076.22 EEQ35563.1 - 1.1e-51 172.5 0.2 3.7e-20 71.5 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ35563.1 - 1.4e-35 121.0 0.0 1.3e-29 101.8 0.0 3.8 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EEQ35563.1 - 1.6e-05 24.8 0.0 0.0027 17.7 0.0 3.6 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 EEQ35563.1 - 0.013 15.5 0.0 0.087 12.8 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.6 EEQ35563.1 - 0.017 15.9 2.8 4.7 8.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_7 PF16367.5 EEQ35563.1 - 0.027 14.6 0.0 5.6 7.2 0.0 3.7 4 0 0 4 4 4 0 RNA recognition motif RNA_bind PF08675.11 EEQ35563.1 - 0.066 13.2 0.0 1 9.4 0.0 2.9 3 0 0 3 3 3 0 RNA binding domain HAP PF03866.13 EEQ35565.1 - 0.32 11.0 8.1 0.059 13.4 1.4 3.0 3 1 0 3 3 3 0 Hydrophobic abundant protein (HAP) DEAD PF00270.29 EEQ35566.1 - 3.4e-45 154.0 0.0 6.5e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ35566.1 - 1e-24 87.0 0.0 7.3e-24 84.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEQ35566.1 - 6.7e-20 71.1 0.2 1.7e-19 69.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EEQ35566.1 - 0.0072 16.3 1.7 0.0076 16.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EEQ35566.1 - 0.033 13.5 3.6 0.14 11.5 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_L22 PF00237.19 EEQ35567.1 - 5.9e-27 93.9 0.0 9.4e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GspH PF12019.8 EEQ35567.1 - 0.1 13.0 0.1 15 6.1 0.0 2.4 2 0 0 2 2 2 0 Type II transport protein GspH SSP160 PF06933.11 EEQ35568.1 - 0.016 13.4 7.8 0.023 12.9 7.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 EEQ35568.1 - 0.84 7.7 5.2 1 7.4 5.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Senescence_reg PF04520.13 EEQ35568.1 - 0.85 10.4 5.6 1.4 9.8 3.9 2.1 1 1 1 2 2 2 0 Senescence regulator Sporozoite_P67 PF05642.11 EEQ35568.1 - 0.86 7.6 11.3 1.2 7.2 11.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Period_C PF12114.8 EEQ35568.1 - 2.5 7.7 7.5 5.5 6.5 7.5 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region NAM-associated PF14303.6 EEQ35568.1 - 5.9 7.6 7.3 0.93 10.2 3.8 1.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Cnd1_N PF12922.7 EEQ35570.1 - 3.6e-48 163.5 0.3 1.1e-47 162.0 0.3 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EEQ35570.1 - 1.2e-44 152.2 3.6 1.4e-39 135.7 0.8 3.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ35570.1 - 4.5e-11 43.0 0.2 0.00045 20.6 0.0 4.6 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 EEQ35570.1 - 2.3e-08 33.6 11.0 0.041 14.1 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat RTP1_C1 PF10363.9 EEQ35570.1 - 2.8e-06 27.5 0.7 0.76 10.0 0.0 4.7 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EEQ35570.1 - 0.00016 22.1 6.3 0.73 10.4 0.1 5.1 5 0 0 5 5 5 1 HEAT-like repeat Cnd3 PF12719.7 EEQ35570.1 - 0.025 13.8 11.9 0.0087 15.3 2.1 3.9 3 2 2 5 5 5 0 Nuclear condensing complex subunits, C-term domain DUF5442 PF17514.2 EEQ35570.1 - 0.15 12.3 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Pkinase PF00069.25 EEQ35571.1 - 6.3e-39 133.9 0.0 9.4e-38 130.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35571.1 - 5.3e-11 42.3 0.0 4.2e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Nop14 PF04147.12 EEQ35571.1 - 1.2 7.3 16.2 1.7 6.8 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.12 EEQ35571.1 - 1.2 8.0 10.6 1.7 7.5 10.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein SDA1 PF05285.12 EEQ35571.1 - 1.5 8.2 15.8 2 7.7 15.8 1.1 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 EEQ35571.1 - 4.5 6.4 5.1 5.9 6.0 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PCMT PF01135.19 EEQ35572.1 - 1.7e-61 207.6 0.0 2.1e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EEQ35572.1 - 1.8e-07 31.1 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ35572.1 - 4.3e-06 27.3 0.0 7.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ35572.1 - 6.5e-05 22.8 0.0 7.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EEQ35572.1 - 0.00028 20.9 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ35572.1 - 0.0012 19.5 0.0 0.002 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EEQ35572.1 - 0.0037 16.9 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EEQ35572.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EEQ35572.1 - 0.012 16.2 0.0 0.021 15.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EEQ35572.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EEQ35572.1 - 0.08 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EEQ35572.1 - 0.12 11.2 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 EEQ35572.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DnaJ PF00226.31 EEQ35573.1 - 4.4e-22 78.0 1.9 1.7e-21 76.1 1.9 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 EEQ35573.1 - 2e-19 68.5 2.7 1.3e-05 24.8 0.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ35573.1 - 3.6e-17 62.3 2.5 0.00041 20.4 0.0 4.6 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ35573.1 - 3.8e-17 60.9 12.2 0.00023 21.1 0.0 7.4 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ35573.1 - 1.3e-14 54.4 7.4 0.012 16.1 0.1 5.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ35573.1 - 1.6e-12 47.1 8.3 0.056 14.3 0.1 7.7 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ35573.1 - 1.6e-12 46.6 7.0 0.0081 16.3 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ35573.1 - 6e-11 42.8 5.0 0.026 15.2 0.2 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ35573.1 - 2e-10 40.2 0.2 0.008 15.8 0.0 4.3 3 1 1 4 4 4 3 TPR repeat TPR_6 PF13174.6 EEQ35573.1 - 5e-10 39.4 8.0 0.71 10.6 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ35573.1 - 9.8e-08 31.9 1.0 0.089 13.2 0.0 5.9 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ35573.1 - 4.1e-06 26.4 2.8 3.9 7.7 0.0 6.4 7 1 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ35573.1 - 1e-05 25.6 12.4 1.3 9.3 0.2 5.7 5 2 1 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 EEQ35573.1 - 3.7e-05 22.6 0.3 0.003 16.3 0.0 2.8 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EEQ35573.1 - 9e-05 22.9 4.0 0.1 13.0 0.2 3.5 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation HrpB1_HrpK PF09613.10 EEQ35573.1 - 0.0009 18.9 0.5 1.8 8.2 0.1 3.6 3 1 0 4 4 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 EEQ35573.1 - 0.016 15.5 3.4 4.2 7.8 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EEQ35573.1 - 0.026 14.6 0.8 36 4.5 0.0 4.5 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat IR1-M PF12185.8 EEQ35573.1 - 0.028 14.3 0.0 0.32 10.9 0.0 2.6 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain TPR_12 PF13424.6 EEQ35573.1 - 0.25 11.6 18.0 0.93 9.8 0.2 5.7 5 2 1 6 6 5 0 Tetratricopeptide repeat DUF1002 PF06207.11 EEQ35573.1 - 0.67 9.4 6.3 0.6 9.6 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) HemY_N PF07219.13 EEQ35573.1 - 0.7 10.1 7.9 0.24 11.6 1.3 3.3 3 1 1 4 4 4 0 HemY protein N-terminus Syntaxin_2 PF14523.6 EEQ35573.1 - 1.6 9.1 6.3 1.4 9.3 0.8 2.7 2 0 0 2 2 2 0 Syntaxin-like protein DUF4363 PF14276.6 EEQ35573.1 - 1.8 8.7 5.9 3 8.0 0.2 3.9 5 1 0 5 5 5 0 Domain of unknown function (DUF4363) YfdX PF10938.8 EEQ35573.1 - 3.4 7.6 16.1 6.9 6.6 0.1 4.8 5 2 0 5 5 4 0 YfdX protein PCRF PF03462.18 EEQ35574.1 - 3.7e-49 167.2 0.4 1.1e-48 165.7 0.0 1.9 3 0 0 3 3 3 1 PCRF domain RF-1 PF00472.20 EEQ35574.1 - 5.5e-34 116.6 1.0 1.3e-33 115.3 1.0 1.6 1 0 0 1 1 1 1 RF-1 domain Abdominal-A PF12407.8 EEQ35574.1 - 0.68 9.6 9.1 1.6 8.4 9.1 1.6 1 0 0 1 1 1 0 Homeobox protein Mito_carr PF00153.27 EEQ35575.1 - 3e-41 139.3 3.7 2.1e-23 82.0 0.1 4.1 4 1 0 4 4 4 3 Mitochondrial carrier protein Helicase_C PF00271.31 EEQ35576.1 - 2.8e-27 95.2 0.9 4.4e-27 94.6 0.4 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ35576.1 - 1.5e-18 67.2 0.2 2.2e-18 66.7 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EEQ35576.1 - 0.053 13.5 0.1 0.075 13.0 0.1 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SMC_N PF02463.19 EEQ35577.1 - 3.4e-21 75.7 6.2 6.2e-20 71.6 6.2 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EEQ35577.1 - 6.2e-15 55.8 3.7 1.3e-13 51.4 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EEQ35577.1 - 5.6e-12 46.6 62.2 6.6e-10 39.8 29.5 5.4 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 EEQ35577.1 - 4.3e-08 33.3 0.4 0.00011 22.1 0.3 3.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ35577.1 - 0.00046 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EEQ35577.1 - 0.027 14.7 0.0 0.027 14.7 0.0 2.9 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit HetR_C PF18460.1 EEQ35577.1 - 0.052 13.5 0.4 0.75 9.8 0.1 2.9 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain ABC_tran PF00005.27 EEQ35577.1 - 0.11 13.0 0.3 0.11 13.0 0.3 5.3 3 2 0 3 3 3 0 ABC transporter DUF5407 PF17401.2 EEQ35577.1 - 0.13 12.5 0.6 4.8 7.5 0.1 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5407) AAA_13 PF13166.6 EEQ35577.1 - 6.6 5.2 68.7 1.2 7.7 6.7 4.6 3 1 1 4 4 4 0 AAA domain NUDIX PF00293.28 EEQ35578.1 - 1.6e-12 47.6 0.4 3.9e-12 46.3 0.4 1.6 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EEQ35578.1 - 0.012 15.6 0.0 0.058 13.4 0.0 2.1 1 1 0 1 1 1 0 NUDIX domain SNARE PF05739.19 EEQ35581.1 - 8.8e-13 48.0 0.1 2.2e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EEQ35581.1 - 1.6e-10 39.9 0.4 4.1e-10 38.6 0.4 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 EEQ35581.1 - 4.3e-05 23.7 1.0 0.38 11.1 0.0 3.5 4 0 0 4 4 4 2 Uncharacterized conserved protein Baculo_PEP_C PF04513.12 EEQ35581.1 - 0.00055 20.0 0.6 0.072 13.1 0.0 2.9 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.25 EEQ35581.1 - 0.0012 18.6 3.9 0.0066 16.2 0.1 2.8 2 1 1 3 3 3 1 Syntaxin NPV_P10 PF05531.12 EEQ35581.1 - 0.013 16.0 1.8 7 7.2 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CdvA PF18822.1 EEQ35581.1 - 0.028 14.3 1.2 0.17 11.7 0.0 2.6 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Syntaxin-18_N PF10496.9 EEQ35581.1 - 0.028 14.7 0.2 0.028 14.7 0.2 2.5 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4988 PF16378.5 EEQ35581.1 - 0.053 13.2 2.8 11 5.6 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function MCPsignal PF00015.21 EEQ35581.1 - 0.074 12.9 5.7 0.31 10.8 0.4 2.9 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Prominin PF05478.11 EEQ35581.1 - 0.088 10.8 0.5 3.8 5.3 0.0 2.3 2 0 0 2 2 2 0 Prominin Adeno_PIX PF03955.14 EEQ35581.1 - 0.2 11.9 2.9 0.49 10.6 2.9 1.6 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) FliT PF05400.13 EEQ35581.1 - 0.9 10.4 8.7 27 5.7 0.1 3.4 2 1 1 3 3 3 0 Flagellar protein FliT SUR7 PF06687.12 EEQ35582.1 - 9.6e-25 87.5 5.5 1.3e-24 87.0 5.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family AAA_22 PF13401.6 EEQ35583.1 - 0.015 15.6 0.1 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EEQ35583.1 - 0.046 14.1 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EEQ35583.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EEQ35583.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Glyco_hydro_18 PF00704.28 EEQ35584.1 - 2.8e-18 66.7 0.7 7.2e-18 65.4 0.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.25 EEQ35585.1 - 9.3e-35 119.9 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ35585.1 - 2.9e-30 105.6 0.0 3.5e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ35585.1 - 9.6e-11 41.9 0.0 1.3e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ35585.1 - 0.00015 21.3 0.0 0.047 13.1 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EEQ35585.1 - 0.00022 20.7 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) APH PF01636.23 EEQ35586.1 - 1.7e-18 67.5 0.0 2.2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ35586.1 - 1.1e-07 31.7 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EEQ35586.1 - 0.00022 20.6 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 2 Fructosamine kinase EcKinase PF02958.20 EEQ35586.1 - 0.0096 15.3 0.1 0.018 14.4 0.0 1.4 2 0 0 2 2 2 1 Ecdysteroid kinase Pkinase PF00069.25 EEQ35586.1 - 0.021 14.2 0.0 0.42 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 EEQ35586.1 - 0.083 11.7 0.0 1.2 7.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Ion_trans_2 PF07885.16 EEQ35588.1 - 1e-23 83.1 25.0 1.1e-14 54.1 8.3 3.1 3 0 0 3 3 3 2 Ion channel GWT1 PF06423.12 EEQ35588.1 - 0.98 9.5 7.9 2.4 8.3 2.0 2.9 2 2 0 2 2 2 0 GWT1 APH PF01636.23 EEQ35590.1 - 4e-12 46.6 0.0 6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EEQ35590.1 - 0.0019 17.6 0.1 0.47 9.8 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Choline_kinase PF01633.20 EEQ35590.1 - 0.007 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4325 PF14213.6 EEQ35590.1 - 0.017 14.8 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) WaaY PF06176.11 EEQ35590.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) RTA1 PF04479.13 EEQ35591.1 - 7.6e-74 247.8 9.2 1e-73 247.4 9.2 1.2 1 0 0 1 1 1 1 RTA1 like protein PGG PF13962.6 EEQ35591.1 - 0.1 12.4 4.3 0.066 13.0 0.7 2.4 2 1 0 2 2 2 0 Domain of unknown function DHHC PF01529.20 EEQ35591.1 - 0.55 10.3 10.6 0.99 9.5 0.9 3.1 3 0 0 3 3 3 0 DHHC palmitoyltransferase Abhydrolase_9_N PF15420.6 EEQ35591.1 - 0.85 9.6 5.8 0.15 12.1 2.1 1.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF3040 PF11239.8 EEQ35591.1 - 7.1 7.0 8.0 24 5.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF3433 PF11915.8 EEQ35592.1 - 1.2e-31 109.0 17.4 2.2e-22 79.3 4.5 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) zf-RanBP PF00641.18 EEQ35593.1 - 2.5e-09 36.3 1.5 4.2e-09 35.6 1.5 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch PF01585.23 EEQ35593.1 - 3.6e-09 36.4 3.2 1e-08 34.9 3.2 1.8 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EEQ35593.1 - 1.8e-05 24.4 0.0 5.2e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 EEQ35593.1 - 0.0011 19.0 2.2 0.0011 19.0 2.2 2.2 2 0 0 2 2 2 1 G-patch domain Rad50_zn_hook PF04423.14 EEQ35593.1 - 0.031 14.1 0.4 0.12 12.2 0.2 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif NCD3G PF07562.14 EEQ35593.1 - 3.1 7.8 6.2 6.8 6.8 1.0 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR RPN2_C PF18004.1 EEQ35595.1 - 0.08 12.9 3.2 0.11 12.4 3.2 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 EEQ35595.1 - 0.11 12.2 1.9 0.14 11.8 1.9 1.2 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.11 EEQ35595.1 - 0.15 10.9 2.0 0.15 10.9 2.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SLAC1 PF03595.17 EEQ35596.1 - 1.6e-94 316.8 58.4 1.9e-94 316.5 58.4 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel T4SS_CagC PF16943.5 EEQ35596.1 - 4.8 7.4 6.9 1.4 9.1 0.3 2.6 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system Pkinase PF00069.25 EEQ35597.1 - 6.3e-20 71.6 0.0 5.3e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35597.1 - 3.7e-06 26.4 0.0 0.28 10.4 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 EEQ35597.1 - 0.017 15.1 0.3 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ35597.1 - 0.024 14.0 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Kinase-like MoaE PF02391.17 EEQ35598.1 - 1.4e-36 125.2 0.1 1.6e-36 125.0 0.1 1.1 1 0 0 1 1 1 1 MoaE protein Ntox25 PF15530.6 EEQ35598.1 - 0.18 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 25 SCO1-SenC PF02630.14 EEQ35599.1 - 1.9e-47 160.6 0.0 2.7e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EEQ35599.1 - 0.0021 18.0 0.0 0.005 16.7 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EEQ35599.1 - 0.027 14.8 0.0 0.057 13.7 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like Yae1_N PF09811.9 EEQ35602.1 - 5.6e-12 45.1 0.4 8.6e-12 44.6 0.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Kdo PF06293.14 EEQ35603.1 - 1.2e-05 24.7 0.1 2.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ35603.1 - 0.00015 21.7 0.1 0.00015 21.7 0.1 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EEQ35603.1 - 0.00072 19.2 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EEQ35603.1 - 0.058 13.0 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 EEQ35603.1 - 0.11 11.8 0.1 0.11 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 EEQ35603.1 - 0.21 10.4 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Spem1 PF15670.5 EEQ35603.1 - 2.5 7.6 11.4 0.52 9.8 2.5 2.4 2 0 0 2 2 2 0 Spermatid maturation protein 1 MFS_1 PF07690.16 EEQ35604.1 - 2.4e-31 109.0 27.2 2.4e-31 109.0 27.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EEQ35604.1 - 3.6e-09 36.4 1.5 3.6e-09 36.4 1.5 2.9 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB AMP-binding PF00501.28 EEQ35605.1 - 3e-157 523.6 0.0 3.4e-68 230.2 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EEQ35605.1 - 1.4e-103 347.0 0.0 7.9e-32 110.5 0.0 5.5 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 EEQ35605.1 - 3.5e-27 94.5 0.4 1.1e-13 51.4 0.1 3.9 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ35605.1 - 0.0045 17.9 0.2 3.3 8.7 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 EEQ35606.1 - 5.8e-44 149.9 0.0 9.2e-22 78.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ35606.1 - 3.8e-24 85.8 26.3 7.3e-23 81.6 12.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EEQ35606.1 - 1.2e-08 34.7 0.0 0.0016 17.9 0.0 3.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEQ35606.1 - 0.00069 19.5 0.4 0.062 13.1 0.2 3.4 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ35606.1 - 0.0012 18.5 0.3 0.0069 16.1 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ35606.1 - 0.0067 16.7 0.2 0.038 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ35606.1 - 0.0092 16.4 0.1 1.2 9.5 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ35606.1 - 0.015 15.2 0.1 0.055 13.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase SNARE PF05739.19 EEQ35606.1 - 0.026 14.5 0.0 0.2 11.6 0.0 2.7 1 0 0 1 1 1 0 SNARE domain MMR_HSR1 PF01926.23 EEQ35606.1 - 0.033 14.3 0.1 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EEQ35606.1 - 0.035 13.7 0.4 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EEQ35606.1 - 0.062 13.5 0.2 19 5.6 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EEQ35606.1 - 0.085 13.3 2.1 0.099 13.1 0.3 2.0 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 EEQ35606.1 - 0.12 12.5 0.1 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 EEQ35606.1 - 0.15 11.8 0.0 2.3 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EEQ35606.1 - 0.18 11.4 0.2 0.61 9.7 0.2 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3040 PF11239.8 EEQ35606.1 - 1.1 9.5 0.0 1.1 9.5 0.0 6.3 7 1 0 7 7 7 0 Protein of unknown function (DUF3040) Abhydrolase_4 PF08386.10 EEQ35609.1 - 5.7e-15 55.3 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EEQ35609.1 - 1.1e-12 48.1 0.0 3.1e-11 43.4 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Beta-lactamase PF00144.24 EEQ35612.1 - 6.7e-48 163.6 0.0 1.3e-46 159.4 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 EEQ35612.1 - 5.6e-10 39.6 0.1 9.2e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Ank_2 PF12796.7 EEQ35613.1 - 3.7e-53 178.1 0.1 8.3e-18 64.8 0.1 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ35613.1 - 1.5e-46 156.2 2.8 1.9e-10 41.1 0.0 6.1 3 1 5 8 8 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EEQ35613.1 - 8.8e-41 136.6 0.4 4.1e-09 36.5 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EEQ35613.1 - 1.2e-39 133.8 1.8 5.7e-09 36.1 0.0 6.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ35613.1 - 1e-35 117.6 0.1 1.3e-06 28.3 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat NACHT PF05729.12 EEQ35613.1 - 2.8e-13 50.1 0.0 6.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EEQ35613.1 - 6.9e-06 26.5 0.0 2.6e-05 24.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ35613.1 - 0.00074 19.8 0.0 0.0027 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EEQ35613.1 - 0.00091 18.5 0.0 0.0024 17.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 EEQ35613.1 - 0.0094 15.2 0.0 0.53 9.5 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain AAA_33 PF13671.6 EEQ35613.1 - 0.026 14.7 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEQ35613.1 - 0.027 14.9 0.0 0.1 13.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA PF00004.29 EEQ35613.1 - 0.037 14.5 0.0 0.13 12.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EEQ35613.1 - 0.2 10.9 0.0 0.45 9.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Fas_alpha_ACP PF18325.1 EEQ35614.1 - 3.7e-65 219.2 0.0 7.1e-65 218.3 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 EEQ35614.1 - 3.2e-39 134.7 0.0 6.1e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 EEQ35614.1 - 8e-21 74.7 0.0 1.9e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EEQ35614.1 - 1.3e-11 44.6 0.0 3.4e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EEQ35614.1 - 0.026 14.4 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 KR domain Aminotran_4 PF01063.19 EEQ35615.1 - 1.9e-29 103.1 0.0 2.5e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV ABC_tran PF00005.27 EEQ35617.1 - 1.3e-47 161.8 0.0 2.5e-28 99.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEQ35617.1 - 4e-35 121.8 25.0 1.5e-24 87.1 12.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EEQ35617.1 - 5.3e-10 39.1 5.2 0.00077 19.0 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEQ35617.1 - 3e-06 27.3 2.2 0.74 9.6 0.1 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ35617.1 - 5.3e-06 26.1 0.5 0.0048 16.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ35617.1 - 2.7e-05 24.1 0.2 0.062 13.2 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 EEQ35617.1 - 2.9e-05 24.5 0.0 0.16 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EEQ35617.1 - 9.2e-05 23.0 2.3 0.18 12.3 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EEQ35617.1 - 0.00012 21.9 0.9 0.22 11.2 0.2 2.2 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EEQ35617.1 - 0.00017 21.6 0.0 0.083 13.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 EEQ35617.1 - 0.0011 19.4 0.1 2 8.9 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ35617.1 - 0.0011 19.2 0.2 1.7 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EEQ35617.1 - 0.0016 18.0 0.1 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 EEQ35617.1 - 0.0029 16.9 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 EEQ35617.1 - 0.0051 17.4 0.0 0.17 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EEQ35617.1 - 0.02 15.1 0.3 3.5 7.8 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EEQ35617.1 - 0.024 14.8 0.1 9.9 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EEQ35617.1 - 0.029 14.4 0.2 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 EEQ35617.1 - 0.036 14.0 0.4 0.21 11.5 0.0 2.3 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EEQ35617.1 - 0.036 13.2 1.7 1.6 7.9 0.1 3.0 2 2 0 2 2 2 0 NB-ARC domain T2SSE PF00437.20 EEQ35617.1 - 0.047 12.7 0.4 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 EEQ35617.1 - 0.069 12.9 0.1 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EEQ35617.1 - 0.071 13.0 0.4 10 6.0 0.1 2.5 2 0 0 2 2 2 0 NTPase IIGP PF05049.13 EEQ35617.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.9 EEQ35617.1 - 0.12 12.1 0.2 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 EEQ35617.1 - 0.16 11.8 0.3 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.25 EEQ35617.1 - 0.18 11.4 0.1 12 5.5 0.1 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 EEQ35617.1 - 0.19 11.5 1.2 3 7.5 0.0 3.0 4 0 0 4 4 3 0 IstB-like ATP binding protein RTA1 PF04479.13 EEQ35618.1 - 2e-53 181.1 6.4 3.4e-53 180.3 6.4 1.4 1 0 0 1 1 1 1 RTA1 like protein DUF4407 PF14362.6 EEQ35618.1 - 0.76 9.1 2.5 1.3 8.3 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) 4HBT_2 PF13279.6 EEQ35619.1 - 6.3e-07 29.9 0.0 9.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CI-B14_5a PF07347.12 EEQ35619.1 - 0.17 11.8 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF1729 PF08354.10 EEQ35620.1 - 6.7e-142 472.6 0.0 9.4e-142 472.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EEQ35620.1 - 2.6e-63 214.5 0.0 4.8e-61 207.0 0.0 2.4 2 0 0 2 2 2 2 Acyl transferase domain FAS_meander PF17951.1 EEQ35620.1 - 7e-35 120.0 0.0 1.3e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 EEQ35620.1 - 5e-28 98.5 0.0 2.9e-27 96.0 0.0 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EEQ35620.1 - 2.9e-22 78.5 0.2 1.8e-21 76.0 0.0 2.2 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EEQ35620.1 - 2.5e-20 73.0 0.0 2.5e-19 69.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FAS_N PF17828.1 EEQ35620.1 - 4.1e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta p450 PF00067.22 EEQ35621.1 - 1.4e-54 185.6 0.0 5.3e-54 183.7 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 AMP-binding PF00501.28 EEQ35622.1 - 0 1201.9 0.0 4.7e-75 252.8 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 EEQ35622.1 - 7.6e-277 918.2 0.0 1.3e-52 179.0 0.0 8.8 8 1 0 8 8 8 7 Condensation domain PP-binding PF00550.25 EEQ35622.1 - 2.9e-55 184.5 6.2 1.4e-10 41.4 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ35622.1 - 1.4e-14 54.8 0.0 0.0089 17.0 0.0 6.1 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain ASC PF00858.24 EEQ35622.1 - 0.16 10.9 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Fis1_TPR_N PF14852.6 EEQ35622.1 - 0.19 11.4 0.1 29 4.5 0.0 2.8 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat DUF5122 PF17164.4 EEQ35622.1 - 0.47 10.8 3.4 34 4.8 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller F-box-like PF12937.7 EEQ35623.1 - 0.0002 21.2 4.2 0.0026 17.6 4.2 2.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ35623.1 - 0.027 14.4 2.1 0.61 10.0 1.8 3.1 2 1 0 2 2 2 0 F-box domain Glyco_hydro_18 PF00704.28 EEQ35624.1 - 9e-50 170.2 0.0 1.6e-26 93.8 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EEQ35624.1 - 0.0001 22.7 1.2 0.0001 22.7 1.2 3.7 4 0 0 4 4 4 2 Chitin recognition protein HAMP_N3 PF18575.1 EEQ35624.1 - 0.023 14.2 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 HAMP N-terminal domain 3 DNase_NucA_NucB PF14040.6 EEQ35624.1 - 0.096 13.1 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB FLYWCH_u PF16662.5 EEQ35625.1 - 0.19 11.8 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein 1 LysM PF01476.20 EEQ35626.1 - 6.8e-27 93.3 0.1 3.6e-08 33.3 0.1 4.3 4 0 0 4 4 4 4 LysM domain Kazal_3 PF18434.1 EEQ35626.1 - 0.35 10.7 1.5 8.6 6.2 0.1 2.6 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain Fungal_trans PF04082.18 EEQ35627.1 - 1.1e-11 44.3 0.9 1.3e-11 44.1 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 EEQ35628.1 - 2.4e-35 122.2 0.0 3.1e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ35628.1 - 5.3e-16 58.9 0.1 2.4e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ35628.1 - 7.4e-06 25.3 0.0 0.00051 19.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EEQ35628.1 - 0.0029 16.9 0.0 0.043 13.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase COX3 PF00510.18 EEQ35628.1 - 0.005 16.7 0.0 0.007 16.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III TrkA_N PF02254.18 EEQ35628.1 - 0.011 16.0 0.0 1.9 8.8 0.0 3.0 3 0 0 3 3 3 0 TrkA-N domain Trp_halogenase PF04820.14 EEQ35628.1 - 0.016 14.1 0.1 1.5 7.6 0.0 2.9 2 1 1 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EEQ35628.1 - 0.025 13.6 0.0 4.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EEQ35628.1 - 0.061 13.6 0.0 8.2 6.7 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Methyltransf_2 PF00891.18 EEQ35629.1 - 0.00019 20.8 0.0 0.00079 18.8 0.0 2.1 2 1 0 2 2 2 1 O-methyltransferase domain HTH_AsnC-type PF13404.6 EEQ35629.1 - 0.078 12.8 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PheRS_DBD3 PF18553.1 EEQ35629.1 - 0.12 12.6 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 PheRS DNA binding domain 3 adh_short PF00106.25 EEQ35630.1 - 1.6e-19 70.1 0.2 2.4e-19 69.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ35630.1 - 3.8e-15 56.1 0.1 5.9e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 EEQ35631.1 - 2e-45 155.3 38.7 2e-45 155.3 38.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ35631.1 - 7.8e-14 51.4 10.7 7.8e-14 51.4 10.7 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EEQ35631.1 - 2.2e-06 26.4 6.0 3.7e-06 25.7 6.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EEQ35631.1 - 5.3e-06 25.0 8.2 5.3e-06 25.0 8.2 2.4 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EEQ35631.1 - 0.0027 16.2 7.1 0.0039 15.7 7.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector ketoacyl-synt PF00109.26 EEQ35632.1 - 1.4e-71 241.1 0.0 2.8e-71 240.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 EEQ35632.1 - 2.7e-69 233.8 0.0 5.1e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EEQ35632.1 - 7.9e-66 222.6 0.0 1.3e-65 221.9 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 EEQ35632.1 - 3.2e-45 154.6 0.0 5.6e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EEQ35632.1 - 1.2e-44 152.4 0.1 8.6e-44 149.6 0.0 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EEQ35632.1 - 1.4e-44 152.9 0.0 3.5e-44 151.6 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ35632.1 - 4.7e-30 104.0 0.2 1.9e-29 102.0 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EEQ35632.1 - 4.6e-21 75.1 0.0 1.6e-20 73.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 EEQ35632.1 - 7.2e-19 68.4 0.0 2.2e-18 66.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EEQ35632.1 - 5.8e-18 65.0 4.8 4.4e-10 39.8 0.1 4.1 4 0 0 4 4 3 2 Phosphopantetheine attachment site Epimerase PF01370.21 EEQ35632.1 - 5e-15 55.6 0.0 1.5e-12 47.5 0.0 2.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 EEQ35632.1 - 3.1e-14 53.4 0.0 9.7e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EEQ35632.1 - 1.2e-13 51.5 0.0 5.8e-13 49.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ35632.1 - 3.3e-12 46.6 0.0 7.4e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ35632.1 - 8.9e-10 39.1 0.0 2.4e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ35632.1 - 9.6e-08 32.0 0.0 2.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EEQ35632.1 - 1.6e-06 27.7 0.1 6e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Ubie_methyltran PF01209.18 EEQ35632.1 - 1e-05 25.0 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 EEQ35632.1 - 2.9e-05 23.6 0.1 6.3e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 EEQ35632.1 - 0.011 14.7 0.0 2.6 7.0 0.0 2.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_33 PF10017.9 EEQ35632.1 - 0.012 14.8 0.1 0.049 12.8 0.0 1.9 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent SAT PF16073.5 EEQ35632.1 - 0.024 14.4 0.5 0.25 11.1 0.5 2.3 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis RrnaAD PF00398.20 EEQ35632.1 - 0.026 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.15 EEQ35632.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase GDP_Man_Dehyd PF16363.5 EEQ35632.1 - 0.2 11.0 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ADH_N PF08240.12 EEQ35633.1 - 5.2e-07 29.5 0.3 3.9e-06 26.7 0.2 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ35633.1 - 0.00037 20.5 0.0 0.00068 19.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.22 EEQ35634.1 - 1e-16 60.8 0.0 4.8e-14 52.0 0.0 2.8 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 EEQ35635.1 - 2.2e-44 152.0 0.0 2.6e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 EEQ35636.1 - 2.3e-07 30.8 8.4 4.2e-07 30.0 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRX_assoc PF16627.5 EEQ35636.1 - 0.028 14.6 1.8 0.054 13.6 0.0 2.4 3 0 0 3 3 3 0 Unstructured region between BRX_N and BRX domain HNH_2 PF13391.6 EEQ35637.1 - 2.9e-12 46.6 0.2 5.4e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.25 EEQ35638.1 - 1.4e-23 83.6 0.0 2.6e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35638.1 - 2.3e-09 36.9 0.0 1.5e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEQ35638.1 - 0.0029 17.0 0.1 0.46 9.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EEQ35638.1 - 0.0062 16.5 1.2 0.093 12.6 0.4 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family ASFV_p27 PF06556.11 EEQ35638.1 - 0.023 14.8 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus Kdo PF06293.14 EEQ35638.1 - 0.37 10.1 2.2 0.42 9.9 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.31 EEQ35639.1 - 2.5e-05 24.4 0.4 4.9e-05 23.4 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ35639.1 - 0.00067 19.9 0.3 0.0013 18.9 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EEQ35639.1 - 0.021 14.9 1.6 0.087 12.9 1.5 1.9 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EEQ35639.1 - 0.095 12.9 0.2 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 MFS_1 PF07690.16 EEQ35640.1 - 2e-29 102.7 55.1 5.3e-28 98.0 55.1 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Lip_prot_lig_C PF10437.9 EEQ35640.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus AMP-binding PF00501.28 EEQ35641.1 - 3e-34 118.3 0.0 5.4e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EEQ35641.1 - 2.5e-32 112.1 0.0 4.5e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EEQ35641.1 - 4.5e-09 36.5 0.0 9.1e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EEQ35641.1 - 7.3e-08 32.2 0.0 2.7e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ35641.1 - 0.031 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EEQ35641.1 - 0.038 13.1 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EEQ35641.1 - 0.12 12.3 0.0 0.41 10.5 0.0 2.0 1 1 0 1 1 1 0 KR domain Aldo_ket_red PF00248.21 EEQ35642.1 - 1e-64 218.6 0.0 5.6e-64 216.2 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4443 PF14544.6 EEQ35642.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) Methyltransf_3 PF01596.17 EEQ35643.1 - 1.9e-31 108.9 0.0 2.2e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EEQ35643.1 - 1.8e-13 51.4 0.0 2.7e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ35643.1 - 5.1e-09 36.1 0.0 6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EEQ35643.1 - 1.3e-07 31.6 0.0 1.6e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EEQ35643.1 - 5e-07 30.3 0.0 7.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EEQ35643.1 - 1.8e-06 27.7 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EEQ35643.1 - 4.6e-05 24.0 0.0 7.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ35643.1 - 7.8e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ35643.1 - 0.0011 19.7 0.0 0.0017 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EEQ35643.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EEQ35643.1 - 0.021 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EEQ35643.1 - 0.031 14.2 0.0 0.057 13.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EEQ35643.1 - 0.093 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EEQ35643.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 NAD_binding_4 PF07993.12 EEQ35644.1 - 3e-29 102.0 0.0 4.5e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EEQ35644.1 - 9.6e-19 67.3 0.0 2e-18 66.2 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EEQ35644.1 - 3.2e-11 43.2 0.0 7.1e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EEQ35644.1 - 3.2e-08 33.8 0.3 2e-07 31.3 0.3 2.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 EEQ35644.1 - 0.00022 21.2 0.1 0.0017 18.3 0.1 2.1 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EEQ35644.1 - 0.00054 19.5 0.0 0.00091 18.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EEQ35644.1 - 0.16 11.1 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein IPT PF01745.16 EEQ35644.1 - 0.21 11.0 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase ADH_N PF08240.12 EEQ35645.1 - 2.5e-23 82.0 6.0 4.2e-23 81.3 6.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ35645.1 - 1.4e-16 60.6 0.0 2.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EEQ35645.1 - 0.00033 20.1 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EEQ35645.1 - 0.0012 18.2 0.8 0.0038 16.5 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 EEQ35645.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.6 EEQ35645.1 - 0.038 13.9 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding zf-C2HCIx2C PF10782.9 EEQ35645.1 - 0.092 12.7 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger DUF1450 PF07293.11 EEQ35645.1 - 0.26 11.1 3.1 4.6 7.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Fungal_trans PF04082.18 EEQ35646.1 - 4.8e-21 75.0 2.2 7.7e-21 74.3 2.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.19 EEQ35647.1 - 8.7e-49 166.5 0.0 1.3e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EEQ35647.1 - 1.3e-37 129.6 0.0 2.1e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EEQ35647.1 - 1.3e-06 27.8 0.8 0.0024 17.0 1.0 2.3 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EEQ35647.1 - 4e-05 23.0 0.4 0.069 12.4 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ35647.1 - 6.5e-05 22.7 1.3 0.00089 18.9 0.8 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ35647.1 - 0.00097 19.3 0.3 0.0032 17.7 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EEQ35647.1 - 0.002 17.2 0.2 0.0037 16.4 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EEQ35647.1 - 0.0035 16.6 0.5 0.0072 15.6 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EEQ35647.1 - 0.004 16.1 0.9 0.0058 15.5 0.9 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 EEQ35647.1 - 0.014 14.6 0.0 0.064 12.5 0.1 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EEQ35647.1 - 0.082 11.6 0.2 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EEQ35647.1 - 0.14 12.1 0.3 0.32 11.0 0.3 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF2738 PF10927.8 EEQ35648.1 - 0.14 11.3 0.1 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2738) Glyco_hydro_18 PF00704.28 EEQ35652.1 - 1.6e-47 162.7 1.7 2.6e-47 162.1 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EEQ35652.1 - 2.4e-13 49.9 0.0 0.014 15.5 0.0 3.8 4 0 0 4 4 4 3 LysM domain Chitin_bind_1 PF00187.19 EEQ35652.1 - 5.9e-06 26.7 3.9 5.9e-06 26.7 3.9 4.5 4 0 0 4 4 4 1 Chitin recognition protein DUF4470 PF14737.6 EEQ35655.1 - 7.7e-30 103.0 0.1 1.4e-29 102.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Suv3_C_1 PF18147.1 EEQ35655.1 - 0.052 13.4 0.2 0.7 9.8 0.1 2.3 2 0 0 2 2 2 0 Suv3 C-terminal domain 1 Abhydrolase_6 PF12697.7 EEQ35656.1 - 0.012 16.3 0.0 0.012 16.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ank_2 PF12796.7 EEQ35657.1 - 6.7e-35 119.5 3.7 1.2e-17 64.2 0.2 4.1 3 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ35657.1 - 4.6e-30 103.6 3.3 1.2e-13 51.2 0.1 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EEQ35657.1 - 6.8e-24 83.2 8.9 0.00023 21.5 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EEQ35657.1 - 8.2e-24 83.4 4.0 3.8e-06 27.1 0.1 5.0 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ35657.1 - 2.1e-23 79.8 2.5 9.7e-05 22.5 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat NACHT PF05729.12 EEQ35657.1 - 3.4e-06 27.1 0.0 7.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EEQ35657.1 - 1.5e-05 25.5 0.0 5.4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EEQ35657.1 - 0.00016 22.0 0.0 0.005 17.1 0.0 3.1 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 EEQ35657.1 - 0.08 13.0 0.0 0.29 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EEQ35657.1 - 0.2 12.1 0.0 0.82 10.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cauli_VI PF01693.16 EEQ35658.1 - 2e-27 95.2 2.8 2.9e-14 53.1 1.3 2.2 2 0 0 2 2 2 2 Caulimovirus viroplasmin CorA PF01544.18 EEQ35659.1 - 0.024 14.0 2.4 0.049 12.9 2.3 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PEMT PF04191.13 EEQ35663.1 - 3e-33 114.4 2.8 3.8e-33 114.1 1.6 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase BRAP2 PF07576.12 EEQ35663.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 RXT2_N PF08595.11 EEQ35664.1 - 3.9e-32 111.4 0.2 3.9e-32 111.4 0.2 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal Ribosomal_L6 PF00347.23 EEQ35665.1 - 4.9e-24 84.8 5.9 1.2e-11 45.1 0.8 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Glutaredoxin PF00462.24 EEQ35666.1 - 6.3e-12 45.5 0.0 1.4e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Abhydrolase_1 PF00561.20 EEQ35667.1 - 2.5e-08 33.9 0.0 5.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ35667.1 - 0.00022 20.6 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DivIC PF04977.15 EEQ35667.1 - 2 8.2 3.4 3.6 7.4 3.4 1.3 1 0 0 1 1 1 0 Septum formation initiator Gryzun PF07919.12 EEQ35668.1 - 7.3e-224 744.9 0.0 8.7e-224 744.7 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 EEQ35668.1 - 1.1e-94 316.8 0.2 2.1e-84 283.2 0.3 2.7 3 0 0 3 3 3 2 Foie gras liver health family 1 Gryzun-like PF12742.7 EEQ35668.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking PhoD PF09423.10 EEQ35669.1 - 3.3e-08 32.9 0.5 0.00025 20.2 0.1 2.7 3 0 0 3 3 3 2 PhoD-like phosphatase DUF3220 PF11516.8 EEQ35669.1 - 0.17 12.1 0.0 0.61 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) Rhomboid PF01694.22 EEQ35670.1 - 2.8e-13 50.1 5.0 4.2e-13 49.6 5.0 1.2 1 0 0 1 1 1 1 Rhomboid family DUF2157 PF09925.9 EEQ35670.1 - 0.071 12.9 0.5 0.21 11.4 0.1 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) CEP63 PF17045.5 EEQ35671.1 - 0.021 14.7 0.1 0.026 14.4 0.1 1.0 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Shugoshin_N PF07558.11 EEQ35671.1 - 0.033 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region NIF PF03031.18 EEQ35672.1 - 3.1e-57 192.7 0.0 4.5e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aminotran_5 PF00266.19 EEQ35673.1 - 2.3e-26 92.6 0.0 2.8e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 EEQ35673.1 - 0.025 14.6 0.1 0.063 13.3 0.1 1.7 1 0 0 1 1 1 0 B12 binding domain DASH_Dad3 PF08656.10 EEQ35674.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad3 HECT PF00632.25 EEQ35675.1 - 1.1e-98 330.5 0.0 1.5e-98 330.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EEQ35675.1 - 2.3e-33 114.0 29.1 4.7e-13 49.0 3.3 4.6 5 0 0 5 5 5 3 WW domain C2 PF00168.30 EEQ35675.1 - 5.8e-18 65.1 0.0 1.5e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain Rrn6 PF10214.9 EEQ35675.1 - 3.7 5.9 15.4 5.1 5.5 15.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RRM_1 PF00076.22 EEQ35676.1 - 3.2e-15 55.7 0.0 5.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 EEQ35676.1 - 0.018 13.9 2.0 0.022 13.7 2.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Med9 PF07544.13 EEQ35676.1 - 0.019 15.0 0.6 0.033 14.3 0.6 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Nup35_RRM_2 PF14605.6 EEQ35676.1 - 0.049 13.7 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif EMP24_GP25L PF01105.24 EEQ35676.1 - 0.063 13.2 1.0 0.09 12.7 1.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD COG6 PF06419.11 EEQ35676.1 - 0.13 10.5 0.3 0.15 10.2 0.3 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 V_ATPase_I PF01496.19 EEQ35676.1 - 0.29 9.0 0.8 0.32 8.9 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 EEQ35676.1 - 1.6 8.5 4.5 2.6 7.9 4.5 1.3 1 0 0 1 1 1 0 Septum formation initiator SUZ PF12752.7 EEQ35677.1 - 2e-14 54.1 13.0 2e-14 54.1 13.0 4.0 3 1 0 3 3 3 1 SUZ domain R3H PF01424.22 EEQ35677.1 - 4.6e-08 32.9 0.0 9.1e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.6 EEQ35678.1 - 0.027 14.5 0.1 0.057 13.4 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Antimicrobial18 PF08130.11 EEQ35678.1 - 0.36 11.0 3.6 8.8 6.5 0.3 2.8 2 0 0 2 2 2 0 Type A lantibiotic family cwf18 PF08315.12 EEQ35679.1 - 1.1e-41 142.7 8.4 1.7e-41 142.0 8.4 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor RR_TM4-6 PF06459.12 EEQ35679.1 - 6.2 6.6 8.2 0.99 9.2 4.1 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PPR_2 PF13041.6 EEQ35680.1 - 1.5e-23 82.7 0.2 2e-07 31.1 0.0 4.7 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.20 EEQ35680.1 - 1.9e-16 59.0 0.0 1.7e-05 24.7 0.0 5.3 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.7 EEQ35680.1 - 5.1e-12 45.3 0.0 2.7e-05 23.8 0.0 4.3 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 EEQ35680.1 - 2.9e-11 43.3 0.1 0.00035 20.6 0.0 3.4 2 1 2 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 EEQ35680.1 - 1.8e-09 37.3 0.0 1.8e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP CTNNB1_binding PF08347.11 EEQ35680.1 - 2.5 8.2 6.4 6.1 7.0 1.4 2.3 2 0 0 2 2 2 0 N-terminal CTNNB1 binding DUF1242 PF06842.12 EEQ35681.1 - 8.7e-14 51.0 1.1 3.9e-13 49.0 1.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.16 EEQ35682.1 - 8e-23 80.3 0.1 1.3e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 EEQ35682.1 - 0.012 16.0 0.4 0.042 14.2 0.0 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 EEQ35682.1 - 0.022 15.3 0.1 0.046 14.2 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-S PF15630.6 EEQ35682.1 - 0.084 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 CENP-S protein CBFD_NFYB_HMF PF00808.23 EEQ35682.1 - 0.086 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone JAB PF01398.21 EEQ35683.1 - 4.7e-20 71.7 0.0 8.2e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EEQ35683.1 - 1e-18 67.8 0.2 1.9e-18 66.9 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 EEQ35683.1 - 8.1e-05 22.7 0.0 0.00019 21.6 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) UTP25 PF06862.12 EEQ35684.1 - 4.7e-189 629.1 0.0 5.6e-189 628.8 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EEQ35684.1 - 0.00048 19.9 0.0 0.021 14.6 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase TPR_20 PF14561.6 EEQ35684.1 - 0.15 12.4 0.0 25 5.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat EamA PF00892.20 EEQ35685.1 - 1.1e-22 80.7 27.4 1.5e-14 54.3 6.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3341 PF11821.8 EEQ35685.1 - 0.079 12.6 0.8 11 5.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) S_2TMBeta PF18153.1 EEQ35685.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain CTP_transf_like PF01467.26 EEQ35686.1 - 9.9e-30 103.6 0.0 2e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 EEQ35686.1 - 0.099 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase PP2C PF00481.21 EEQ35687.1 - 2.2e-81 273.3 0.0 3.5e-81 272.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Roughex PF06020.11 EEQ35687.1 - 0.053 12.6 4.8 0.076 12.1 4.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Acetyltransf_1 PF00583.25 EEQ35688.1 - 8e-13 48.7 0.2 1e-12 48.3 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ35688.1 - 3.6e-10 39.9 0.1 4.3e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ35688.1 - 1.1e-09 38.5 0.4 1.6e-09 38.0 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ35688.1 - 1.1e-06 28.5 0.1 1.8e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EEQ35688.1 - 9e-06 25.8 0.3 1.2e-05 25.4 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EEQ35688.1 - 0.00085 19.4 0.3 0.0015 18.6 0.3 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EEQ35688.1 - 0.0095 16.1 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EEQ35688.1 - 0.017 14.8 0.3 0.028 14.1 0.3 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ MOZART1 PF12554.8 EEQ35689.1 - 4.5e-22 77.6 2.2 7.4e-22 76.9 2.2 1.4 1 1 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated CUE PF02845.16 EEQ35690.1 - 2.3e-10 40.0 0.0 3.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain HA2 PF04408.23 EEQ35691.1 - 3.3e-17 62.7 0.0 7.9e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EEQ35691.1 - 9.6e-14 51.5 0.0 2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EEQ35691.1 - 7.2e-12 45.6 0.0 1.8e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ35691.1 - 1.5e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEQ35691.1 - 8.8e-05 22.8 0.1 0.00026 21.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEQ35691.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ35691.1 - 0.00023 21.5 0.0 0.00055 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEQ35691.1 - 0.0064 15.6 0.0 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.19 EEQ35691.1 - 0.009 15.6 0.1 0.099 12.2 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EEQ35691.1 - 0.025 14.7 0.1 0.18 12.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ35691.1 - 0.084 13.3 0.1 0.2 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EEQ35691.1 - 0.12 12.8 0.0 0.38 11.3 0.0 1.9 2 0 0 2 2 1 0 ABC transporter PITH PF06201.13 EEQ35692.1 - 9.4e-42 142.8 0.0 1.1e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain DUF1970 PF09301.10 EEQ35692.1 - 0.16 12.2 0.1 0.42 10.9 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) Snf7 PF03357.21 EEQ35693.1 - 1.1e-29 103.2 9.4 1.3e-29 103.0 9.4 1.0 1 0 0 1 1 1 1 Snf7 Parathyroid PF01279.17 EEQ35693.1 - 0.021 15.4 0.1 0.061 13.9 0.1 1.8 1 0 0 1 1 1 0 Parathyroid hormone family DHDPS PF00701.22 EEQ35693.1 - 0.033 12.9 0.1 0.05 12.3 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family HSCB_C PF07743.13 EEQ35693.1 - 1.1 9.8 10.1 0.92 10.0 2.0 2.6 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain AAA PF00004.29 EEQ35694.1 - 8.4e-91 301.3 0.0 1.6e-45 154.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ35694.1 - 1.2e-18 66.7 2.1 5e-09 35.8 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EEQ35694.1 - 1.2e-13 51.8 1.3 0.0002 21.8 0.0 4.6 3 2 0 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 EEQ35694.1 - 3.3e-13 49.7 0.0 5.8e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ35694.1 - 1.3e-11 45.0 0.3 0.0075 16.5 0.0 5.3 2 2 2 4 4 4 2 AAA domain AAA_2 PF07724.14 EEQ35694.1 - 9.8e-11 42.1 0.0 0.00032 20.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EEQ35694.1 - 1.3e-10 41.6 0.0 4.3e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EEQ35694.1 - 3.1e-10 40.2 0.2 0.00086 19.3 0.0 4.3 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EEQ35694.1 - 4.3e-09 36.0 0.0 0.00015 21.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 EEQ35694.1 - 5.8e-08 33.1 0.0 0.0064 16.9 0.0 2.9 2 1 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EEQ35694.1 - 2e-07 31.1 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EEQ35694.1 - 2.7e-07 31.2 0.0 0.01 16.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EEQ35694.1 - 4.2e-07 29.5 0.5 0.022 14.1 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EEQ35694.1 - 4.5e-07 30.3 0.0 0.0073 16.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EEQ35694.1 - 8.4e-07 28.9 0.1 0.062 13.0 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 EEQ35694.1 - 9.4e-07 28.3 0.0 0.033 13.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.11 EEQ35694.1 - 1.2e-06 28.5 0.0 0.004 17.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EEQ35694.1 - 1.1e-05 25.5 0.0 0.14 12.1 0.0 3.3 3 0 0 3 3 3 2 NACHT domain TsaE PF02367.17 EEQ35694.1 - 1.1e-05 25.5 0.0 0.08 13.0 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EEQ35694.1 - 1.5e-05 25.1 0.0 0.081 12.8 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 EEQ35694.1 - 2.9e-05 23.7 0.0 0.091 12.3 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 EEQ35694.1 - 3.7e-05 24.3 0.0 0.18 12.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Cytidylate_kin2 PF13189.6 EEQ35694.1 - 5.2e-05 23.5 0.0 0.017 15.3 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family ATPase PF06745.13 EEQ35694.1 - 5.7e-05 22.6 0.2 0.46 9.8 0.0 3.4 3 1 1 4 4 4 2 KaiC AAA_25 PF13481.6 EEQ35694.1 - 7.2e-05 22.4 0.6 1.3 8.6 0.0 3.9 3 1 1 4 4 4 2 AAA domain AAA_17 PF13207.6 EEQ35694.1 - 8.1e-05 23.1 0.0 0.19 12.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EEQ35694.1 - 0.00011 22.0 0.0 0.38 10.4 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 EEQ35694.1 - 0.00038 19.7 0.0 0.99 8.5 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain AFG1_ATPase PF03969.16 EEQ35694.1 - 0.0004 19.4 0.0 0.082 11.8 0.0 2.5 2 0 0 2 2 2 1 AFG1-like ATPase TniB PF05621.11 EEQ35694.1 - 0.00041 19.8 0.0 0.13 11.6 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein PhoH PF02562.16 EEQ35694.1 - 0.00045 19.7 0.0 0.61 9.5 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 EEQ35694.1 - 0.00056 19.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain SKI PF01202.22 EEQ35694.1 - 0.00067 19.8 0.0 0.8 9.8 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase AAA_24 PF13479.6 EEQ35694.1 - 0.001 18.8 0.0 0.88 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EEQ35694.1 - 0.0011 18.9 0.0 1.8 8.4 0.0 3.3 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 EEQ35694.1 - 0.0013 17.9 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.18 EEQ35694.1 - 0.0013 18.5 0.0 0.89 9.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 EEQ35694.1 - 0.0015 17.8 0.0 0.051 12.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 EEQ35694.1 - 0.0015 18.6 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 EEQ35694.1 - 0.012 15.9 1.5 5.8 7.2 0.4 3.1 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 EEQ35694.1 - 0.019 14.8 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 EEQ35694.1 - 0.022 14.8 0.0 8.1 6.4 0.0 2.9 2 1 0 3 3 2 0 Type III restriction enzyme, res subunit Vps4_C PF09336.10 EEQ35694.1 - 0.048 13.7 0.1 1.7 8.7 0.1 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain IPT PF01745.16 EEQ35694.1 - 0.057 12.8 0.1 7.6 5.8 0.0 2.6 3 0 0 3 3 2 0 Isopentenyl transferase DUF2075 PF09848.9 EEQ35694.1 - 0.072 12.3 0.0 4.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EEQ35694.1 - 0.11 12.4 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 EEQ35694.1 - 0.14 11.9 0.3 18 5.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 EEQ35694.1 - 0.15 12.5 0.0 4.8 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain BOP1NT PF08145.12 EEQ35695.1 - 4.1e-104 348.1 5.4 7.5e-104 347.2 5.4 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EEQ35695.1 - 4.5e-20 71.6 8.1 1.1e-09 38.7 0.2 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ35695.1 - 4e-05 23.8 0.1 0.015 15.5 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EEQ35695.1 - 0.01 16.3 2.2 8.1 7.1 0.0 4.5 4 0 0 4 4 4 0 PQQ-like domain Zn_clus PF00172.18 EEQ35696.1 - 3.1e-08 33.6 8.1 7.1e-08 32.5 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leo1 PF04004.13 EEQ35697.1 - 4e-30 104.9 0.5 2.2e-29 102.4 0.5 2.2 1 1 0 1 1 1 1 Leo1-like protein DTHCT PF08070.11 EEQ35697.1 - 5.7 7.7 26.6 3.2 8.5 3.0 4.2 3 1 1 4 4 4 0 DTHCT (NUC029) region Mob1_phocein PF03637.17 EEQ35698.1 - 7.8e-39 133.4 0.1 3.7e-32 111.7 0.0 2.5 1 1 1 2 2 2 2 Mob1/phocein family IF-2B PF01008.17 EEQ35699.1 - 1.8e-55 188.2 8.0 2.1e-47 161.7 3.4 3.0 2 1 0 2 2 2 2 Initiation factor 2 subunit family SUIM_assoc PF16619.5 EEQ35699.1 - 0.0029 17.6 3.9 0.0062 16.6 3.9 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF4834 PF16118.5 EEQ35699.1 - 0.14 13.2 0.8 0.28 12.1 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) 3HCDH_N PF02737.18 EEQ35699.1 - 0.33 10.8 2.2 0.41 10.5 0.3 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosom_S12_S23 PF00164.25 EEQ35700.1 - 3.2e-50 168.5 1.0 4e-50 168.2 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 EEQ35701.1 - 2.4e-19 68.9 0.4 9.3e-19 67.0 0.1 2.2 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Tcp11 PF05794.13 EEQ35701.1 - 0.038 13.1 0.1 5.9 5.9 0.0 2.1 1 1 1 2 2 2 0 T-complex protein 11 AIM5 PF17050.5 EEQ35702.1 - 5.8e-10 39.8 0.1 9.5e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 PulG PF11773.8 EEQ35702.1 - 0.1 12.4 0.4 0.26 11.1 0.3 1.6 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Ribosomal_L17 PF01196.19 EEQ35703.1 - 4.5e-33 114.0 0.0 7.3e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Metallophos_2 PF12850.7 EEQ35704.1 - 1.6e-12 47.9 0.0 1.9e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF202 PF02656.15 EEQ35708.1 - 4.5e-14 52.7 5.1 4.5e-14 52.7 5.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 EEQ35708.1 - 0.74 9.7 11.9 0.089 12.6 6.7 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5337) DUF4131 PF13567.6 EEQ35708.1 - 4.1 7.0 7.7 8.1 6.1 6.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Tctex-1 PF03645.13 EEQ35709.1 - 1.2e-30 105.8 0.0 1.7e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family Self-incomp_S1 PF05938.11 EEQ35709.1 - 0.073 13.6 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 WD40 PF00400.32 EEQ35710.1 - 7.9e-34 115.1 17.6 1.2e-09 38.6 0.2 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ35710.1 - 5e-08 33.1 0.8 0.017 15.4 0.0 4.5 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ35710.1 - 3.2e-06 26.1 3.3 0.074 11.7 0.1 4.5 2 1 1 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EEQ35710.1 - 5.9e-06 25.4 1.1 1.9e-05 23.8 0.1 2.2 2 1 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 EEQ35710.1 - 0.001 18.1 0.1 1.5 7.7 0.0 3.8 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 EEQ35710.1 - 0.017 14.8 1.5 0.79 9.4 0.1 3.3 2 1 1 3 3 3 0 TUP1-like enhancer of split HPS3_N PF14761.6 EEQ35710.1 - 0.07 12.7 0.0 0.52 9.8 0.0 2.3 1 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Nucleoporin_N PF08801.11 EEQ35710.1 - 0.073 11.8 0.0 1.4 7.6 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like Frtz PF11768.8 EEQ35710.1 - 0.12 10.6 0.0 0.21 9.8 0.0 1.3 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1854 PF08909.11 EEQ35710.1 - 0.21 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) Filament PF00038.21 EEQ35711.1 - 0.031 13.9 1.6 0.05 13.2 1.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein FadA PF09403.10 EEQ35711.1 - 0.83 10.2 2.8 1.5 9.4 0.7 2.1 1 1 1 2 2 2 0 Adhesion protein FadA p450 PF00067.22 EEQ35713.1 - 1e-66 225.6 0.0 1.3e-66 225.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.6 EEQ35713.1 - 0.2 11.9 0.4 5 7.4 0.2 2.5 2 0 0 2 2 2 0 Stirrup p450 PF00067.22 EEQ35714.1 - 1.2e-29 103.4 0.2 1.5e-29 103.0 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 HNH_2 PF13391.6 EEQ35715.1 - 3e-13 49.7 0.7 6.2e-13 48.7 0.7 1.6 1 0 0 1 1 1 1 HNH endonuclease TFIIF_alpha PF05793.12 EEQ35715.1 - 1.1 7.7 3.4 1.6 7.2 3.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ketoacyl-synt PF00109.26 EEQ35716.1 - 2.3e-75 253.4 0.0 4e-75 252.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EEQ35716.1 - 5.1e-74 249.0 0.0 1.3e-73 247.6 0.0 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EEQ35716.1 - 8.8e-34 117.4 0.0 1.6e-33 116.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ35716.1 - 1.6e-31 108.8 0.5 3.3e-31 107.7 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EEQ35716.1 - 7e-26 91.8 0.0 2.8e-25 89.8 0.0 2.1 2 1 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 EEQ35716.1 - 6.7e-14 51.8 0.1 1.4e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 EEQ35716.1 - 1.9e-13 50.5 7.6 7.6e-07 29.4 0.6 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EEQ35716.1 - 3.3e-07 30.7 0.1 8.1e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 EEQ35716.1 - 0.00061 20.5 0.4 0.0048 17.5 0.1 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EEQ35716.1 - 0.046 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 alpha/beta hydrolase fold FMO-like PF00743.19 EEQ35717.1 - 2.9e-50 171.2 0.0 8.2e-42 143.3 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EEQ35717.1 - 3.4e-13 49.5 0.0 6.6e-11 42.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ35717.1 - 7.3e-09 35.3 0.0 2.4e-05 23.7 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ35717.1 - 7.1e-07 28.7 0.1 2.2e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EEQ35717.1 - 0.0017 18.4 0.0 0.33 10.9 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EEQ35717.1 - 0.046 14.3 0.6 0.18 12.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EEQ35717.1 - 0.053 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EEQ35717.1 - 0.092 12.3 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Inp1 PF12634.7 EEQ35717.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 adh_short PF00106.25 EEQ35718.1 - 1.6e-35 122.3 0.3 1.5e-34 119.2 0.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ35718.1 - 8e-33 113.9 0.3 2e-30 106.1 0.3 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ35718.1 - 1.1e-08 35.2 0.1 2.3e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EEQ35718.1 - 0.022 15.0 0.1 0.039 14.2 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EEQ35718.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 EEQ35718.1 - 0.25 11.9 0.7 0.5 11.0 0.7 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fasciclin PF02469.22 EEQ35719.1 - 4.9e-34 117.3 0.0 1.4e-20 73.8 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Cu-oxidase_3 PF07732.15 EEQ35720.1 - 6.5e-37 126.2 1.4 1.2e-36 125.3 0.4 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EEQ35720.1 - 1.4e-23 83.2 13.7 1.4e-20 73.5 1.4 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EEQ35720.1 - 2e-18 67.0 0.0 6e-18 65.5 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase DUF4087 PF13316.6 EEQ35720.1 - 0.13 12.7 0.1 0.8 10.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4087) Methyltransf_2 PF00891.18 EEQ35721.1 - 9.9e-24 83.8 0.0 1.8e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 EEQ35721.1 - 0.053 14.3 0.0 0.35 11.6 0.0 2.4 3 1 0 3 3 3 0 Methyltransferase domain MFS_1 PF07690.16 EEQ35722.1 - 1.2e-35 123.1 46.3 5.5e-35 120.9 46.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ35722.1 - 4.8e-12 45.5 1.5 4.8e-12 45.5 1.5 3.5 2 1 1 3 3 3 2 Sugar (and other) transporter TFIIE-A_C PF11521.8 EEQ35722.1 - 0.043 14.1 1.7 0.075 13.3 1.7 1.3 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Gram_pos_anchor PF00746.21 EEQ35722.1 - 0.4 10.7 0.1 0.4 10.7 0.1 3.3 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Fungal_trans PF04082.18 EEQ35723.1 - 9.3e-15 54.4 0.8 1.5e-14 53.7 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ35723.1 - 7.2e-09 35.6 12.0 1.6e-08 34.5 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 EEQ35724.1 - 2.8e-18 66.0 1.5 4.4e-18 65.4 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EEQ35724.1 - 1.5e-06 28.2 0.0 4e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like p450 PF00067.22 EEQ35726.1 - 2.5e-21 76.0 0.1 2.1e-19 69.7 0.0 2.4 3 0 0 3 3 3 2 Cytochrome P450 TcpE PF12648.7 EEQ35727.1 - 4.9 7.7 9.4 0.55 10.8 2.0 2.5 2 1 0 2 2 2 0 TcpE family 3Beta_HSD PF01073.19 EEQ35728.1 - 2.1e-50 171.3 0.0 2.6e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EEQ35728.1 - 2.1e-27 96.2 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EEQ35728.1 - 9.3e-16 58.1 0.0 1e-13 51.4 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EEQ35728.1 - 8.4e-09 35.0 0.7 2.6e-07 30.1 0.0 2.1 1 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EEQ35728.1 - 4.2e-06 26.1 0.0 7.1e-06 25.3 0.0 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EEQ35728.1 - 0.00012 21.3 0.1 0.00083 18.6 0.1 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EEQ35728.1 - 0.0014 18.6 0.4 0.011 15.6 0.4 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EEQ35728.1 - 0.0087 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EEQ35728.1 - 0.029 13.8 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 EEQ35728.1 - 0.095 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EEQ35728.1 - 0.15 12.3 0.2 0.27 11.5 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MASE1 PF05231.14 EEQ35728.1 - 0.17 11.0 0.6 0.26 10.4 0.6 1.2 1 0 0 1 1 1 0 MASE1 PglD_N PF17836.1 EEQ35728.1 - 0.17 12.5 0.3 0.42 11.3 0.2 1.7 2 0 0 2 2 1 0 PglD N-terminal domain Transket_pyr PF02779.24 EEQ35729.1 - 6.9e-40 136.6 0.0 1.3e-39 135.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EEQ35729.1 - 8.2e-31 106.5 0.1 1.8e-30 105.4 0.1 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain BMC PF00936.19 EEQ35729.1 - 0.13 12.2 0.4 14 5.8 0.0 2.7 1 1 1 2 2 2 0 BMC domain MPS2 PF17060.5 EEQ35731.1 - 0.0056 16.0 2.9 0.0056 16.0 2.9 3.1 1 1 2 3 3 3 1 Monopolar spindle protein 2 UPF0242 PF06785.11 EEQ35731.1 - 0.04 14.0 30.8 0.13 12.4 5.3 3.2 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 EEQ35731.1 - 0.35 9.9 23.0 0.026 13.6 5.3 2.5 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 XLF PF09302.11 EEQ35731.1 - 1.1 9.3 11.4 0.63 10.2 0.2 3.6 3 2 0 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF3972 PF13118.6 EEQ35731.1 - 1.2 9.6 13.0 1.7 9.1 1.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3972) CRR7 PF12095.8 EEQ35731.1 - 2.5 8.6 17.3 0.19 12.2 2.7 3.4 3 2 1 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF641 PF04859.12 EEQ35731.1 - 8.3 6.8 27.4 0.071 13.4 3.4 4.3 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) DUF21 PF01595.20 EEQ35732.1 - 8.8e-24 84.2 0.0 6.5e-23 81.3 0.0 2.0 1 1 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EEQ35732.1 - 0.0014 19.1 0.1 0.51 10.8 0.0 3.1 2 0 0 2 2 2 2 CBS domain CCDC106 PF15794.5 EEQ35732.1 - 3.6 7.3 9.8 9.6 5.8 9.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 His_Phos_1 PF00300.22 EEQ35733.1 - 3e-16 59.7 0.0 5.4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HECT PF00632.25 EEQ35734.1 - 3.4e-69 233.7 0.0 2.5e-68 230.8 0.0 2.1 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EEQ35734.1 - 2.4e-22 78.9 2.3 6.1e-22 77.6 2.3 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Tis11B_N PF04553.12 EEQ35734.1 - 5.8 7.5 6.3 7.9 7.1 0.6 3.2 3 0 0 3 3 3 0 Tis11B like protein, N terminus zf-C2H2_2 PF12756.7 EEQ35735.1 - 4.1e-36 123.3 12.2 1.9e-29 102.0 2.2 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EEQ35735.1 - 2.3e-11 43.7 9.5 1.8e-05 24.9 2.5 4.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ35735.1 - 9.2e-08 32.2 8.5 7.9e-06 26.1 2.7 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Cytochrome-c551 PF10643.9 EEQ35735.1 - 0.024 14.2 0.3 4.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 zf-C2H2_6 PF13912.6 EEQ35735.1 - 0.031 14.3 0.2 0.031 14.3 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EEQ35735.1 - 0.11 13.0 0.3 0.11 13.0 0.3 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF2024 PF09630.10 EEQ35735.1 - 0.13 12.1 0.2 0.13 12.1 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) Cytochrome_CBB3 PF13442.6 EEQ35735.1 - 0.39 11.1 3.2 19 5.7 0.2 3.0 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Abhydrolase_3 PF07859.13 EEQ35737.1 - 0.00018 21.5 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EEQ35737.1 - 0.0023 17.6 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EEQ35737.1 - 0.0029 17.1 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pkinase PF00069.25 EEQ35738.1 - 1.2e-69 234.6 0.0 1.6e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35738.1 - 8.4e-31 107.2 0.0 1.1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ35738.1 - 9.4e-05 21.9 0.0 0.00022 20.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEQ35738.1 - 0.00061 18.8 0.0 0.014 14.4 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EEQ35738.1 - 0.008 16.1 0.1 0.018 15.0 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EEQ35738.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.6 EEQ35739.1 - 6.2e-31 108.1 0.0 5.9e-30 104.9 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2HC_2 PF13913.6 EEQ35740.1 - 0.0017 18.2 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 EEQ35740.1 - 0.0081 16.9 0.4 0.02 15.7 0.4 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.12 EEQ35740.1 - 0.016 15.5 0.1 0.033 14.5 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 EEQ35740.1 - 0.096 13.2 0.4 0.21 12.1 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3671 PF12420.8 EEQ35741.1 - 0.00083 19.4 0.2 0.00083 19.4 0.2 2.2 2 1 0 2 2 2 1 Protein of unknown function DUF1129 PF06570.11 EEQ35741.1 - 0.0032 17.0 0.1 0.0062 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Sigma_reg_N PF13800.6 EEQ35741.1 - 0.01 16.1 1.1 0.01 16.1 1.1 1.7 2 0 0 2 2 1 0 Sigma factor regulator N-terminal CrgA PF06781.12 EEQ35741.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Cell division protein CrgA DUF4079 PF13301.6 EEQ35741.1 - 0.02 15.1 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF5305 PF17231.2 EEQ35741.1 - 0.042 13.2 0.1 0.057 12.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Orf78 PF06024.12 EEQ35741.1 - 0.075 13.3 0.0 0.075 13.3 0.0 1.6 2 0 0 2 2 1 0 Orf78 (ac78) EphA2_TM PF14575.6 EEQ35741.1 - 0.082 13.8 0.1 0.23 12.4 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Synaptobrevin PF00957.21 EEQ35741.1 - 0.14 12.0 1.4 0.32 10.8 1.4 1.6 1 0 0 1 1 1 0 Synaptobrevin Insulin_TMD PF17870.1 EEQ35741.1 - 0.15 12.2 4.1 0.68 10.1 4.1 2.1 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment LapA_dom PF06305.11 EEQ35741.1 - 0.21 11.5 0.2 0.21 11.5 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PspB PF06667.12 EEQ35741.1 - 0.61 10.2 0.1 0.61 10.2 0.1 2.4 2 1 0 2 2 2 0 Phage shock protein B FAD_binding_3 PF01494.19 EEQ35743.1 - 2.8e-11 43.3 0.2 1.1e-06 28.1 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain Imm_superinfect PF14373.6 EEQ35743.1 - 0.00075 19.4 2.5 0.00075 19.4 2.5 2.0 2 0 0 2 2 2 1 Superinfection immunity protein FAD_binding_2 PF00890.24 EEQ35743.1 - 0.016 14.3 0.1 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EEQ35743.1 - 0.09 12.0 0.0 0.24 10.6 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EEQ35745.1 - 8.6e-43 146.6 42.6 8.6e-43 146.6 42.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ35745.1 - 0.0012 17.4 6.8 0.0012 17.4 6.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 EEQ35746.1 - 4.2e-09 35.8 0.0 7.5e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ35746.1 - 3.3e-08 33.5 9.3 3.3e-08 33.5 9.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 EEQ35747.1 - 1.5e-68 231.1 0.0 3.3e-68 230.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EEQ35747.1 - 7.6e-48 162.8 0.0 1.8e-47 161.6 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EEQ35747.1 - 1.5e-45 155.7 0.0 2.5e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EEQ35747.1 - 2.9e-41 142.0 0.1 5.3e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ35747.1 - 1.3e-29 102.6 0.2 4.2e-29 100.9 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EEQ35747.1 - 1.4e-18 67.4 0.0 3.4e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EEQ35747.1 - 1.5e-15 57.6 0.0 3.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EEQ35747.1 - 1.6e-14 54.3 0.0 5.7e-14 52.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ35747.1 - 1.2e-12 48.3 0.0 3.7e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ35747.1 - 1.7e-10 41.0 0.0 4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ35747.1 - 7.5e-09 35.6 0.0 3.1e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 EEQ35747.1 - 2.9e-08 33.4 0.0 6.6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ubie_methyltran PF01209.18 EEQ35747.1 - 1.6e-05 24.4 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 EEQ35747.1 - 2.4e-05 24.6 0.2 6.7e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EEQ35747.1 - 0.00021 20.7 0.0 0.00047 19.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 EEQ35747.1 - 0.0059 16.4 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 EEQ35747.1 - 0.021 14.5 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 EEQ35747.1 - 0.025 15.6 0.0 0.077 14.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 EEQ35747.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AA_permease_2 PF13520.6 EEQ35748.1 - 2.6e-57 194.6 40.9 3.4e-57 194.2 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ35748.1 - 9.3e-22 77.2 37.7 1.2e-21 76.9 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease Plasmod_dom_1 PF09715.10 EEQ35748.1 - 0.91 9.6 3.4 0.9 9.6 0.4 2.5 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF2569 PF10754.9 EEQ35749.1 - 0.025 15.0 5.1 0.076 13.5 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) Na_Ca_ex PF01699.24 EEQ35749.1 - 0.082 12.9 6.0 0.28 11.2 5.9 1.9 1 1 0 1 1 1 0 Sodium/calcium exchanger protein DUF3237 PF11578.8 EEQ35750.1 - 5.9e-07 29.4 0.1 7.9e-07 29.0 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) DLH PF01738.18 EEQ35751.1 - 5.9e-09 35.8 0.0 8.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Cu-oxidase_3 PF07732.15 EEQ35752.1 - 8.5e-45 151.6 0.3 5.4e-44 149.0 0.3 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EEQ35752.1 - 8.4e-40 135.7 5.1 7.4e-38 129.4 0.1 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EEQ35752.1 - 9.8e-34 116.8 0.0 3e-33 115.2 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase LysM PF01476.20 EEQ35754.1 - 1.2e-10 41.3 0.1 6.9e-06 26.0 0.0 3.5 4 0 0 4 4 4 3 LysM domain MFS_1 PF07690.16 EEQ35755.1 - 5.5e-26 91.3 50.3 3.2e-17 62.5 18.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ35755.1 - 0.00024 20.1 21.3 0.015 14.2 5.6 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter DUF373 PF04123.13 EEQ35755.1 - 1.2 8.5 6.1 8 5.8 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Cutinase PF01083.22 EEQ35756.1 - 7.7e-43 146.5 0.6 1.1e-42 146.0 0.6 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EEQ35756.1 - 6.4e-06 25.9 0.1 1.2e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 PE-PPE domain VirJ PF06057.11 EEQ35756.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) RED_N PF07808.13 EEQ35758.1 - 3.1e-08 33.5 4.9 3.1e-08 33.5 4.9 2.7 2 1 0 2 2 2 1 RED-like protein N-terminal region PspA_IM30 PF04012.12 EEQ35758.1 - 0.0039 16.8 0.3 0.01 15.4 0.3 1.6 1 0 0 1 1 1 1 PspA/IM30 family Lsm_interact PF05391.11 EEQ35758.1 - 0.0074 15.7 1.3 0.032 13.7 1.3 2.2 1 0 0 1 1 1 1 Lsm interaction motif CD24 PF14984.6 EEQ35758.1 - 3.3 8.0 5.4 7.8 6.8 5.4 1.6 1 0 0 1 1 1 0 CD24 protein Glyco_hydro_cc PF11790.8 EEQ35760.1 - 1.1e-58 198.7 0.2 1.4e-58 198.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Peptidase_S8 PF00082.22 EEQ35761.1 - 0.0096 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DUF1230 PF06799.11 EEQ35761.1 - 0.028 14.5 0.5 0.043 13.9 0.5 1.4 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 Myb_DNA-binding PF00249.31 EEQ35762.1 - 7.7e-28 96.4 8.3 3.5e-13 49.5 0.2 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ35762.1 - 1.1e-23 83.2 1.6 1.9e-13 50.5 0.0 3.4 1 1 2 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EEQ35762.1 - 0.0068 16.5 0.0 0.98 9.6 0.0 2.8 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EEQ35762.1 - 0.0082 16.5 3.8 2 8.8 0.1 3.3 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain FAD_binding_4 PF01565.23 EEQ35764.1 - 6.6e-06 25.9 0.0 1.8e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EEQ35764.1 - 0.0063 16.6 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like PsbT PF01405.17 EEQ35764.1 - 0.04 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein YycH PF07435.11 EEQ35764.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 YycH protein adh_short PF00106.25 EEQ35765.1 - 3e-32 111.6 0.1 5.9e-32 110.7 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ35765.1 - 4.8e-20 72.1 0.2 1e-19 71.0 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ35765.1 - 2.8e-08 33.9 0.1 4e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 KR domain AA_permease PF00324.21 EEQ35766.1 - 4e-120 401.6 33.5 4.5e-120 401.5 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ35766.1 - 2.3e-31 109.1 37.1 2.8e-31 108.8 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease HTH_38 PF13936.6 EEQ35767.1 - 6.1e-06 25.9 0.8 3.5e-05 23.5 0.4 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EEQ35767.1 - 7.1e-06 25.7 0.1 1.8e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 EEQ35767.1 - 1.6e-05 25.4 2.0 0.00016 22.2 0.1 2.4 1 1 1 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EEQ35767.1 - 0.00025 20.7 0.1 0.0016 18.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_7 PF02796.15 EEQ35767.1 - 0.0012 18.9 0.2 1.2 9.3 0.1 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase Sigma70_r4 PF04545.16 EEQ35767.1 - 0.0015 18.0 0.3 0.15 11.6 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Tnp_Tc3_2 PF01498.18 EEQ35767.1 - 0.0056 16.9 0.1 0.03 14.6 0.0 2.2 2 0 0 2 2 2 1 Transposase GerE PF00196.19 EEQ35767.1 - 0.0078 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 EEQ35767.1 - 0.016 15.3 2.0 0.029 14.5 0.2 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_31 PF13560.6 EEQ35767.1 - 0.02 15.2 3.1 0.023 15.1 0.4 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 EEQ35767.1 - 0.072 13.2 0.3 0.2 11.7 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix HTH_Mga PF08280.11 EEQ35767.1 - 0.091 12.8 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain DUF433 PF04255.14 EEQ35767.1 - 0.099 12.5 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF433) KGG PF10685.9 EEQ35768.1 - 4.6e-22 77.6 16.4 1.5e-10 41.0 0.7 3.5 4 0 0 4 4 4 3 Stress-induced bacterial acidophilic repeat motif Aminotran_5 PF00266.19 EEQ35769.1 - 8.2e-17 61.2 0.0 1.1e-15 57.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EEQ35769.1 - 0.019 14.2 0.0 0.042 13.0 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II UNC-93 PF05978.16 EEQ35770.1 - 0.0001 22.0 3.0 0.0001 22.0 3.0 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 WD40 PF00400.32 EEQ35771.1 - 7.9e-57 187.9 13.5 1.2e-10 41.8 0.5 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ35771.1 - 1.1e-22 80.1 0.0 0.00086 19.6 0.0 5.9 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ35771.1 - 3.3e-09 36.0 1.1 0.19 10.3 0.0 5.1 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ35771.1 - 1.1e-08 34.5 0.3 0.047 12.6 0.0 4.7 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EEQ35771.1 - 4.9e-05 22.8 0.0 0.00049 19.5 0.0 2.4 2 1 1 3 3 3 1 WD40-like domain PD40 PF07676.12 EEQ35771.1 - 0.0004 20.2 3.3 0.77 9.8 0.0 5.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 EEQ35771.1 - 0.0047 16.1 0.2 0.33 10.0 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF1513) Nbas_N PF15492.6 EEQ35771.1 - 0.058 12.7 0.2 10 5.3 0.0 3.1 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 EEQ35771.1 - 0.073 11.4 0.0 0.15 10.4 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 EEQ35771.1 - 0.11 11.4 0.3 11 4.9 0.1 3.0 3 2 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Exo_endo_phos PF03372.23 EEQ35772.1 - 1.2e-12 47.9 0.1 1.8e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thi4 PF01946.17 EEQ35773.1 - 2.1e-108 361.0 0.0 2.5e-108 360.7 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EEQ35773.1 - 6.4e-07 29.3 0.0 8.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ35773.1 - 1.4e-05 25.2 0.3 8.4e-05 22.7 0.2 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EEQ35773.1 - 0.00018 20.7 0.3 0.00033 19.8 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EEQ35773.1 - 0.0017 17.6 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ35773.1 - 0.0034 17.4 0.1 0.015 15.3 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EEQ35773.1 - 0.076 11.9 0.2 0.11 11.4 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EEQ35773.1 - 0.086 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EEQ35773.1 - 0.12 11.4 0.3 0.3 10.1 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 EEQ35773.1 - 0.19 11.0 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ppx-GppA PF02541.16 EEQ35775.1 - 1.9e-40 139.1 0.0 3.2e-40 138.4 0.0 1.4 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Proteasome PF00227.26 EEQ35777.1 - 1.5e-46 158.3 0.2 1.8e-46 158.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.25 EEQ35778.1 - 1.7e-31 109.6 0.0 1.4e-29 103.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35778.1 - 1.3e-06 27.9 0.0 0.04 13.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EEQ35778.1 - 0.013 15.4 0.3 0.12 12.3 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pil1 PF13805.6 EEQ35779.1 - 3.5e-83 279.1 4.1 3.9e-83 279.0 4.1 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 SWI-SNF_Ssr4 PF08549.10 EEQ35781.1 - 3.2e-222 740.1 17.8 1.9e-220 734.3 17.8 2.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) GATase PF00117.28 EEQ35782.1 - 8.1e-09 35.5 0.0 6.2e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EEQ35782.1 - 0.02 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 HTS PF04204.16 EEQ35782.1 - 0.02 13.9 0.0 0.4 9.6 0.0 2.0 1 1 0 2 2 2 0 Homoserine O-succinyltransferase AMP-binding PF00501.28 EEQ35783.1 - 4.4e-137 457.1 0.0 2.7e-69 233.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EEQ35783.1 - 4.7e-73 246.4 0.0 1.1e-38 133.1 0.0 3.2 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 EEQ35783.1 - 1.3e-23 83.2 0.2 2.9e-11 43.5 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ35783.1 - 3.5e-09 37.5 0.0 0.00033 21.6 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Asn_synthase PF00733.21 EEQ35784.1 - 6.1e-66 223.5 0.0 8.5e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EEQ35784.1 - 3.1e-36 124.0 0.0 6.4e-36 123.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EEQ35784.1 - 1.3e-30 106.3 0.0 3.8e-30 104.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EEQ35784.1 - 0.00034 20.2 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.16 EEQ35784.1 - 0.003 16.4 0.0 0.0046 15.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EEQ35784.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD synthase AIRS_C PF02769.22 EEQ35785.1 - 0.19 11.9 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain adh_short PF00106.25 EEQ35786.1 - 2.7e-21 75.9 0.0 5.7e-20 71.6 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ35786.1 - 1.3e-11 44.5 0.0 2.1e-10 40.6 0.0 2.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EEQ35786.1 - 3.1e-06 27.2 0.0 5.5e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EEQ35786.1 - 0.00025 20.6 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EEQ35786.1 - 0.0042 17.0 0.1 0.0087 16.0 0.1 1.5 1 0 0 1 1 1 1 KR domain FAD_binding_4 PF01565.23 EEQ35787.1 - 2e-17 63.2 2.8 2.9e-17 62.7 2.1 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EEQ35787.1 - 9.7e-07 28.8 0.1 1.8e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like RNA_pol_Rpb2_6 PF00562.28 EEQ35788.1 - 9.8e-117 390.3 0.0 1.3e-116 389.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EEQ35788.1 - 1.5e-38 132.4 0.0 2.2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EEQ35788.1 - 1.5e-27 95.6 0.0 3.1e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EEQ35788.1 - 1.9e-26 92.9 0.0 3.6e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EEQ35788.1 - 2.4e-25 88.3 0.0 5.4e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EEQ35788.1 - 9.7e-16 58.0 0.0 1.3e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 ketoacyl-synt PF00109.26 EEQ35789.1 - 2.1e-59 201.2 0.0 7.5e-59 199.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EEQ35789.1 - 2.3e-58 197.1 0.0 1.2e-57 194.8 0.0 2.3 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EEQ35789.1 - 5.1e-56 190.1 0.0 7.5e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EEQ35789.1 - 2.7e-52 178.3 0.0 6e-52 177.1 0.0 1.6 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EEQ35789.1 - 4e-27 94.6 0.1 2.4e-26 92.1 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EEQ35789.1 - 8.6e-27 93.8 0.0 2e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EEQ35789.1 - 9.7e-19 68.0 0.0 7e-18 65.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EEQ35789.1 - 8.3e-17 62.5 0.0 1.1e-14 55.6 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EEQ35789.1 - 2e-16 60.1 0.0 7.1e-16 58.4 0.0 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EEQ35789.1 - 6.8e-13 48.5 0.1 1.1e-11 44.6 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 EEQ35789.1 - 9.9e-13 48.3 0.1 8e-12 45.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ35789.1 - 3.3e-11 43.2 0.0 8.1e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ35789.1 - 3.2e-09 37.3 0.1 4.1e-08 33.8 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ35789.1 - 3.4e-09 37.3 0.0 1.3e-08 35.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EEQ35789.1 - 0.00059 19.6 0.0 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase Ubie_methyltran PF01209.18 EEQ35789.1 - 0.0068 15.8 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 EEQ35789.1 - 0.046 14.1 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site ADH_N PF08240.12 EEQ35789.1 - 0.056 13.3 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DREV PF05219.12 EEQ35789.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Thiolase_N PF00108.23 EEQ35789.1 - 0.1 11.9 0.2 0.23 10.8 0.2 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_24 PF13578.6 EEQ35789.1 - 0.11 13.5 0.0 0.84 10.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Arf PF00025.21 EEQ35790.1 - 2e-38 131.6 0.0 1.5e-35 122.2 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 EEQ35790.1 - 5e-16 58.7 0.0 6.7e-14 51.8 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EEQ35790.1 - 6.6e-12 45.7 0.0 2.3e-10 40.7 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EEQ35790.1 - 7e-06 26.1 0.0 2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEQ35790.1 - 6.7e-05 22.4 0.0 0.00036 19.9 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EEQ35790.1 - 8.2e-05 21.9 0.0 0.00023 20.4 0.0 1.6 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 EEQ35790.1 - 0.0002 20.9 0.0 0.0015 18.0 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 EEQ35790.1 - 0.00071 19.6 0.1 0.0012 18.8 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 EEQ35790.1 - 0.014 15.4 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Dynamin family RCR PF12273.8 EEQ35791.1 - 3.3e-17 63.2 17.5 3.3e-17 63.2 17.5 2.3 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red CYYR1 PF10873.8 EEQ35791.1 - 0.0024 18.3 0.2 0.0042 17.5 0.2 1.3 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 WBP-1 PF11669.8 EEQ35791.1 - 0.0032 18.1 0.1 0.0052 17.4 0.1 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 DUF4381 PF14316.6 EEQ35791.1 - 0.029 14.6 0.1 0.043 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ion_trans_2 PF07885.16 EEQ35791.1 - 0.034 14.1 0.2 0.053 13.5 0.2 1.3 1 0 0 1 1 1 0 Ion channel SARAF PF06682.12 EEQ35791.1 - 0.069 12.8 7.2 0.15 11.7 7.2 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Corona_S2 PF01601.16 EEQ35792.1 - 3 6.2 19.1 4.1 5.8 19.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein MFS_1 PF07690.16 EEQ35793.1 - 5e-15 55.3 28.3 5e-15 55.3 28.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ35793.1 - 5.6e-06 25.5 2.5 5.6e-06 25.5 2.5 4.2 2 2 2 4 4 4 4 Sugar (and other) transporter CwfJ_C_1 PF04677.15 EEQ35795.1 - 3.2e-24 85.1 0.0 9.3e-24 83.6 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EEQ35795.1 - 2.9e-16 60.1 0.5 7.5e-16 58.8 0.5 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 EEQ35796.1 - 1e-188 628.6 5.8 2.4e-187 624.1 0.0 3.5 4 0 0 4 4 4 2 Down-regulated in metastasis Sec7_N PF12783.7 EEQ35796.1 - 0.12 12.3 6.3 5.4 6.9 0.0 5.2 5 1 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 EEQ35796.1 - 1.1 9.8 6.7 12 6.5 0.0 6.0 8 0 0 8 8 8 0 HEAT repeat zf-DNL PF05180.12 EEQ35797.1 - 4.7e-28 96.9 0.4 7.4e-28 96.3 0.4 1.3 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.18 EEQ35797.1 - 0.0082 16.0 1.3 1.1 9.2 0.2 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) zf-CSL PF05207.13 EEQ35797.1 - 0.011 15.4 0.2 0.021 14.6 0.2 1.4 1 0 0 1 1 1 0 CSL zinc finger Elf1 PF05129.13 EEQ35797.1 - 0.044 13.8 0.2 0.08 13.0 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 EEQ35797.1 - 0.43 10.5 3.2 0.55 10.2 0.1 2.4 3 0 0 3 3 3 0 zinc-ribbon domain Cullin PF00888.22 EEQ35798.1 - 6.2e-201 669.2 7.7 8.7e-201 668.7 7.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EEQ35798.1 - 1.8e-28 98.3 1.2 3e-27 94.4 0.5 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain HWE_HK PF07536.14 EEQ35798.1 - 0.024 15.4 0.3 0.18 12.5 0.0 2.6 3 0 0 3 3 3 0 HWE histidine kinase Rrf2 PF02082.20 EEQ35798.1 - 0.11 12.9 0.2 0.52 10.7 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator DUF1737 PF08410.10 EEQ35798.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) SLD5_C PF16922.5 EEQ35799.1 - 3.6e-09 36.7 0.1 6.5e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EEQ35799.1 - 0.0015 19.0 0.6 0.0034 17.8 0.5 1.5 1 1 0 1 1 1 1 GINS complex protein Rhodanese PF00581.20 EEQ35800.1 - 9.5e-14 51.8 0.1 2.1e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Iso_dh PF00180.20 EEQ35802.1 - 3.4e-86 289.5 0.0 4e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4875 PF16175.5 EEQ35802.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4875) PTS_EIIC_2 PF13303.6 EEQ35802.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DNA_pol_phi PF04931.13 EEQ35803.1 - 7.4e-213 708.9 45.9 1.9e-210 700.9 45.9 2.1 1 1 0 1 1 1 1 DNA polymerase phi TPT PF03151.16 EEQ35804.1 - 1.2e-22 80.6 20.3 1.7e-22 80.2 20.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EEQ35804.1 - 7.6e-07 29.4 39.1 3e-05 24.2 17.5 2.4 2 1 0 2 2 2 2 EamA-like transporter family AD PF09793.9 EEQ35805.1 - 7.4e-24 83.7 0.0 1.4e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain RRM_1 PF00076.22 EEQ35806.1 - 3.9e-18 65.0 0.0 6.6e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 EEQ35806.1 - 7.7 6.0 20.4 16 5.0 20.4 1.5 1 0 0 1 1 1 0 Spt20 family 6PGD PF00393.19 EEQ35807.1 - 1.9e-127 424.6 0.0 2.4e-127 424.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EEQ35807.1 - 2.7e-49 167.4 0.0 3.9e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EEQ35807.1 - 0.055 13.7 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EEQ35807.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_C15 PF01470.17 EEQ35808.1 - 1.7e-12 48.0 0.0 2.4e-06 27.9 0.0 2.5 2 1 0 2 2 2 2 Pyroglutamyl peptidase FLYWCH_u PF16662.5 EEQ35809.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein 1 Porphobil_deam PF01379.20 EEQ35812.1 - 3.8e-08 33.1 0.0 6.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EEQ35812.1 - 5.3e-06 26.7 0.0 8.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Spidroin_N PF16763.5 EEQ35812.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term AA_permease PF00324.21 EEQ35813.1 - 7.3e-112 374.4 38.0 8.9e-112 374.1 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ35813.1 - 4e-27 95.1 40.2 4.8e-27 94.9 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease SPC12 PF06645.13 EEQ35813.1 - 0.09 12.9 0.5 0.09 12.9 0.5 3.3 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) UPF0261 PF06792.11 EEQ35813.1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) HET PF06985.11 EEQ35814.1 - 1e-28 100.5 0.2 2.1e-23 83.3 0.1 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) TIP_N PF12457.8 EEQ35814.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal AP_endonuc_2 PF01261.24 EEQ35816.1 - 3.1e-26 92.1 0.0 4.5e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.12 EEQ35817.1 - 1.1e-43 148.1 0.0 2.3e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 EEQ35817.1 - 1.4e-15 57.2 0.0 9.5e-15 54.5 0.0 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 EEQ35817.1 - 7.4e-11 41.9 0.0 1.5e-09 37.6 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35817.1 - 9.8e-05 21.7 0.0 0.00036 19.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 EEQ35817.1 - 0.001 19.2 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein PAN_4 PF14295.6 EEQ35817.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 PAN domain Pox_Ag35 PF03286.14 EEQ35818.1 - 6.6 6.5 12.1 2.2 8.1 3.3 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Hexokinase_1 PF00349.21 EEQ35819.1 - 3e-57 193.7 0.0 4e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EEQ35819.1 - 1.3e-46 159.0 0.0 2.2e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Hexokinase DUF3237 PF11578.8 EEQ35821.1 - 3.9e-10 39.7 0.0 4.4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ADH_N PF08240.12 EEQ35822.1 - 1.7e-12 47.2 1.8 8.3e-12 45.0 1.8 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ35822.1 - 1.7e-07 31.2 0.0 4.5e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 EEQ35823.1 - 1.5e-11 43.8 0.3 2.9e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ35823.1 - 9e-10 38.5 8.6 1.7e-09 37.6 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 EEQ35824.1 - 4.8e-09 36.4 1.9 0.0039 17.4 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ35824.1 - 1.9e-07 31.5 0.2 3.5 8.2 0.0 6.3 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ35824.1 - 7.5e-05 22.5 0.0 0.36 11.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ35824.1 - 8.9e-05 22.3 0.9 1.2 9.4 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ35824.1 - 0.00062 19.5 0.1 7.5 6.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ35824.1 - 0.0014 18.1 0.2 0.19 11.1 0.0 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 EEQ35824.1 - 0.0018 19.0 1.9 18 6.4 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ35824.1 - 0.0078 15.9 0.0 0.024 14.3 0.0 1.9 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 EEQ35824.1 - 0.0079 16.0 0.0 5.9 6.9 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ35824.1 - 0.018 15.7 0.0 31 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EEQ35824.1 - 1.1 10.1 3.9 12 6.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-UBR PF02207.20 EEQ35825.1 - 8.8e-16 57.8 19.4 8.8e-16 57.8 19.4 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EEQ35825.1 - 4.1e-05 23.3 0.0 0.00012 21.7 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 EEQ35825.1 - 0.018 15.4 1.0 0.018 15.4 1.0 4.1 3 0 0 3 3 3 0 Ring finger domain ELL PF10390.9 EEQ35825.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Mago-bind PF09282.10 EEQ35826.1 - 3.4e-14 52.4 2.6 5.6e-14 51.7 2.6 1.4 1 0 0 1 1 1 1 Mago binding Ndc1_Nup PF09531.10 EEQ35826.1 - 2.2 6.9 4.2 2.2 6.9 4.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Amino_oxidase PF01593.24 EEQ35827.1 - 7.2e-31 108.0 0.0 8.5e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EEQ35827.1 - 2e-14 53.6 0.0 5.4e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ35827.1 - 2.9e-09 37.0 0.1 7.5e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ35827.1 - 5.9e-05 22.4 0.0 0.00093 18.5 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ35827.1 - 0.00034 20.6 0.1 0.0023 17.9 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EEQ35827.1 - 0.0011 17.7 0.1 0.0028 16.4 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EEQ35827.1 - 0.0015 18.0 0.1 0.0023 17.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 EEQ35827.1 - 0.0023 16.8 0.0 0.0041 16.0 0.0 1.4 1 0 0 1 1 1 1 MCRA family FAD_binding_2 PF00890.24 EEQ35827.1 - 0.0076 15.4 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EEQ35827.1 - 0.012 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Glucokinase PF02685.16 EEQ35827.1 - 0.033 13.2 0.2 0.16 10.9 0.0 1.9 2 0 0 2 2 2 0 Glucokinase FMO-like PF00743.19 EEQ35827.1 - 0.04 12.4 0.0 0.056 11.9 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 EEQ35827.1 - 0.067 13.8 0.0 0.26 11.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EEQ35827.1 - 0.17 10.9 0.3 0.38 9.8 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.6 EEQ35827.1 - 0.2 10.8 0.2 0.44 9.6 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EEQ35827.1 - 0.21 10.8 0.0 0.4 9.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-CCCH_2 PF14608.6 EEQ35828.1 - 2.1e-11 43.8 53.7 4.2e-06 27.0 10.1 5.5 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 EEQ35828.1 - 0.019 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) p450 PF00067.22 EEQ35829.1 - 1.3e-61 208.8 0.0 7.3e-44 150.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 CSTF_C PF14304.6 EEQ35829.1 - 0.14 11.7 0.3 0.3 10.7 0.3 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal LEDGF PF11467.8 EEQ35830.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) 2-Hacid_dh_C PF02826.19 EEQ35831.1 - 9.6e-54 181.4 0.0 1.5e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ35831.1 - 2.6e-36 124.3 0.1 4.3e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EEQ35831.1 - 0.0012 18.2 2.9 0.0071 15.7 2.9 2.1 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 EEQ35831.1 - 0.0026 18.3 0.0 0.013 16.0 0.0 2.1 2 1 0 2 2 2 1 XdhC Rossmann domain ACT PF01842.25 EEQ35831.1 - 0.011 15.5 0.6 0.031 14.0 0.0 2.2 2 0 0 2 2 2 0 ACT domain AdoHcyase_NAD PF00670.21 EEQ35831.1 - 0.013 15.6 0.2 0.052 13.6 0.0 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 EEQ35831.1 - 0.032 14.8 0.2 7.4 7.2 0.0 2.8 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fe-ADH PF00465.19 EEQ35832.1 - 1.5e-102 343.1 0.0 1.9e-102 342.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EEQ35832.1 - 9.2e-16 58.3 0.0 1.7e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 EEQ35832.1 - 0.0022 17.7 0.1 0.0041 16.8 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Ank_2 PF12796.7 EEQ35833.1 - 5.1e-64 212.9 11.9 7.6e-14 52.1 0.4 6.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ35833.1 - 9.1e-60 198.3 15.4 2.3e-12 47.1 0.2 8.4 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ35833.1 - 3.9e-54 174.3 9.0 9.9e-06 25.5 0.0 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_5 PF13857.6 EEQ35833.1 - 1.9e-45 152.3 17.6 1.4e-05 25.2 0.0 10.2 3 1 8 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 EEQ35833.1 - 2.4e-44 147.9 13.5 1.7e-05 25.0 0.0 11.9 12 0 0 12 12 12 8 Ankyrin repeat DUF4265 PF14085.6 EEQ35833.1 - 0.035 14.1 0.1 0.63 10.0 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4265) La_HTH_kDCL PF18177.1 EEQ35833.1 - 0.13 12.6 1.0 14 6.1 0.0 3.4 2 1 1 3 3 3 0 La HTH in kinetoplastid DICER domain Ig_GlcNase PF18368.1 EEQ35834.1 - 7.7e-34 116.0 0.1 2.3e-33 114.5 0.1 1.9 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 EEQ35834.1 - 3.1e-12 47.1 0.0 9.8e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EEQ35834.1 - 3.3e-06 27.1 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Mannosidase_ig PF17786.1 EEQ35834.1 - 0.00042 20.9 0.0 0.0017 18.9 0.0 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_C PF02836.17 EEQ35834.1 - 0.086 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Kin17_mid PF10357.9 EEQ35835.1 - 2.4e-47 160.0 1.3 2.4e-47 160.0 1.3 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EEQ35835.1 - 2.4e-05 24.5 0.9 5.8e-05 23.3 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEQ35835.1 - 0.00048 20.3 0.3 0.00048 20.3 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EEQ35835.1 - 0.013 15.8 3.6 0.014 15.7 0.4 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Glyoxalase PF00903.25 EEQ35836.1 - 1.2e-38 132.2 0.1 9.8e-19 67.8 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EEQ35836.1 - 1e-17 64.4 0.0 3.8e-06 27.1 0.0 4.0 1 1 3 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EEQ35836.1 - 4e-08 34.0 0.0 0.00057 20.6 0.0 3.1 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EEQ35836.1 - 1.9e-07 31.4 0.0 0.0084 16.2 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EEQ35836.1 - 0.021 14.8 0.3 4.5 7.2 0.0 3.5 4 0 0 4 4 4 0 Glyoxalase-like domain CppA_N PF14506.6 EEQ35836.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 CppA N-terminal Exonuc_VII_L PF02601.15 EEQ35838.1 - 0.0056 16.3 0.8 0.0093 15.6 0.4 1.4 1 1 0 1 1 1 1 Exonuclease VII, large subunit Apolipoprotein PF01442.18 EEQ35838.1 - 0.028 14.3 0.5 0.049 13.5 0.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1759 PF03564.15 EEQ35838.1 - 0.16 11.9 0.6 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Arrestin_C PF02752.22 EEQ35839.1 - 3e-15 56.8 0.0 7.4e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EEQ35839.1 - 2.5e-09 37.4 0.0 1.5e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Hexapep PF00132.24 EEQ35840.1 - 1.8e-06 27.4 11.2 4.9e-05 22.9 2.9 4.6 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EEQ35840.1 - 0.0063 16.2 0.4 0.0063 16.2 0.4 2.7 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase An_peroxidase PF03098.15 EEQ35841.1 - 1.4e-40 139.4 0.0 2.4e-22 79.2 0.0 3.2 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 EEQ35841.1 - 7.8e-09 34.8 0.0 7.4e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.9 EEQ35843.1 - 3.3e-99 331.9 0.2 4.3e-99 331.5 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_61 PF03443.14 EEQ35844.1 - 0.006 16.5 0.0 0.014 15.3 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 61 MARVEL PF01284.23 EEQ35845.1 - 4.1e-07 30.1 3.0 5.9e-07 29.6 3.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Patched PF02460.18 EEQ35845.1 - 1.1 7.3 4.5 1.5 6.8 4.5 1.1 1 0 0 1 1 1 0 Patched family PGA2 PF07543.12 EEQ35846.1 - 9.1e-46 155.3 1.3 1.1e-45 155.1 1.3 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 Remorin_C PF03763.13 EEQ35846.1 - 0.45 10.4 6.9 0.23 11.3 1.4 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region DUF3245 PF11595.8 EEQ35846.1 - 9.9 6.6 12.8 0.33 11.4 5.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) CENP-S PF15630.6 EEQ35847.1 - 1.4e-30 105.5 0.0 1.8e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EEQ35847.1 - 1.3e-10 41.3 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EEQ35847.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated MMS1_N PF10433.9 EEQ35848.1 - 9.6e-120 400.5 0.0 2e-119 399.5 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EEQ35848.1 - 8.5e-64 215.9 0.0 9.3e-63 212.5 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region Plug_translocon PF10559.9 EEQ35848.1 - 0.048 13.5 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 Plug domain of Sec61p PQQ_3 PF13570.6 EEQ35848.1 - 0.32 11.5 5.9 0.44 11.1 0.1 4.3 5 0 0 5 5 5 0 PQQ-like domain NAD_binding_2 PF03446.15 EEQ35849.1 - 2.9e-35 121.8 0.1 5.1e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EEQ35849.1 - 1.8e-27 96.0 0.0 3e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EEQ35849.1 - 2.3e-06 28.1 0.0 7.3e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EEQ35849.1 - 0.0016 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EEQ35849.1 - 0.0085 16.9 0.0 0.018 15.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ABC_membrane PF00664.23 EEQ35850.1 - 5.1e-63 213.3 36.1 9.3e-38 130.4 11.1 3.7 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ35850.1 - 2.7e-44 151.0 0.1 2.3e-25 89.7 0.0 4.4 2 2 1 3 3 3 3 ABC transporter SMC_N PF02463.19 EEQ35850.1 - 7.2e-15 55.0 0.0 6.6e-06 25.7 1.6 3.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EEQ35850.1 - 0.00061 20.0 1.1 0.39 11.0 0.2 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EEQ35850.1 - 0.00073 19.8 2.2 0.0087 16.3 0.0 3.3 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 EEQ35850.1 - 0.0035 17.3 0.0 0.0082 16.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EEQ35850.1 - 0.0038 17.0 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 EEQ35850.1 - 0.0061 17.0 0.1 0.072 13.5 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 EEQ35850.1 - 0.0084 15.9 0.1 0.047 13.5 0.0 2.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ35850.1 - 0.009 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EEQ35850.1 - 0.013 15.9 0.1 7.9 6.9 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEQ35850.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EEQ35850.1 - 0.023 14.3 0.2 0.094 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EEQ35850.1 - 0.032 14.7 0.7 0.12 12.9 0.8 1.8 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 EEQ35850.1 - 0.052 13.3 0.1 1.9 8.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EEQ35850.1 - 0.16 12.5 0.1 0.33 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain FAD_binding_4 PF01565.23 EEQ35851.1 - 1.8e-23 82.8 6.0 3.3e-23 81.9 6.0 1.5 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 EEQ35852.1 - 5.1e-36 124.4 0.0 2.9e-22 79.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 EEQ35853.1 - 1.5e-24 86.7 50.4 2.5e-24 85.8 46.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 EEQ35854.1 - 4.4e-07 29.9 11.4 4.4e-07 29.9 11.4 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ35855.1 - 7.1e-16 58.0 0.0 2e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ35855.1 - 1.7e-09 37.6 8.9 3.3e-09 36.7 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 EEQ35855.1 - 0.18 10.2 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Trp_DMAT PF11991.8 EEQ35856.1 - 4.4e-108 361.9 0.0 1.2e-107 360.5 0.0 1.6 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.28 EEQ35857.1 - 4.2e-141 470.4 0.0 3.3e-74 250.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EEQ35857.1 - 2.1e-86 290.4 0.0 8.7e-49 166.4 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EEQ35857.1 - 2.2e-27 95.2 0.3 2.1e-09 37.6 0.0 3.6 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEQ35857.1 - 4e-05 24.5 0.0 0.00018 22.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EEQ35857.1 - 0.027 13.1 0.0 0.059 12.0 0.0 1.5 1 0 0 1 1 1 0 Transferase family Methyltransf_2 PF00891.18 EEQ35858.1 - 1.3e-29 103.0 0.0 1.9e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EEQ35858.1 - 0.00085 19.3 0.1 0.03 14.3 0.0 2.3 1 1 1 2 2 2 1 Dimerisation domain Methyltransf_12 PF08242.12 EEQ35858.1 - 0.065 14.0 0.0 0.18 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DIT1_PvcA PF05141.12 EEQ35859.1 - 5.6e-67 226.1 0.0 9.5e-67 225.4 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Transferase PF02458.15 EEQ35859.1 - 1e-14 54.1 0.0 1.2e-09 37.3 0.0 2.9 2 1 0 2 2 2 2 Transferase family PP-binding PF00550.25 EEQ35859.1 - 2.6e-07 30.9 0.0 6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 EEQ35859.1 - 3.5e-06 25.9 0.0 0.013 14.1 0.0 3.1 1 1 2 3 3 3 2 AMP-binding enzyme MFS_1 PF07690.16 EEQ35860.1 - 5.8e-18 64.9 59.2 1.6e-14 53.6 28.4 2.7 2 1 0 3 3 3 2 Major Facilitator Superfamily MVL PF12151.8 EEQ35861.1 - 4.1 7.3 6.7 1.7 8.6 2.4 2.2 2 0 0 2 2 2 0 Mannan-binding protein MFS_1 PF07690.16 EEQ35862.1 - 6.1e-13 48.4 70.5 2.1e-12 46.7 62.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ35862.1 - 0.00076 18.0 25.2 0.00099 17.6 25.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WSC PF01822.19 EEQ35863.1 - 2.1e-47 159.2 44.8 1e-17 64.1 11.4 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.11 EEQ35863.1 - 1.5e-27 96.4 0.0 1.9e-26 92.7 0.0 2.5 2 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EEQ35863.1 - 2.7e-22 78.9 0.9 1.1e-21 77.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 EEQ35863.1 - 0.048 13.7 0.2 0.55 10.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Glyco_hydro_16 PF00722.21 EEQ35864.1 - 2.2e-16 59.8 0.8 1.9e-15 56.8 0.0 2.4 1 1 2 3 3 3 1 Glycosyl hydrolases family 16 Cortexin PF11057.8 EEQ35864.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Cortexin of kidney Glyco_trans_2_3 PF13632.6 EEQ35865.1 - 2.4e-53 181.0 2.4 2.4e-53 181.0 2.4 3.0 2 1 1 3 3 3 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EEQ35865.1 - 0.0039 17.0 0.0 0.044 13.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 WSC PF01822.19 EEQ35866.1 - 1.9e-37 127.3 31.1 1.7e-18 66.6 11.4 2.5 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.23 EEQ35866.1 - 1.1e-20 74.3 0.2 2.4e-20 73.2 0.2 1.5 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.18 EEQ35866.1 - 0.02 14.9 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Photosystem I psaG / psaK Flg_new PF09479.10 EEQ35866.1 - 0.17 12.1 2.5 1.5 9.1 0.2 3.2 3 0 0 3 3 3 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Pterin_4a PF01329.19 EEQ35867.1 - 7.5e-21 74.1 0.1 1e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Baculo_ME53 PF06061.11 EEQ35867.1 - 0.031 13.5 0.1 0.039 13.2 0.1 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 FR47 PF08445.10 EEQ35869.1 - 0.0071 16.3 0.1 0.83 9.7 0.0 2.3 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.25 EEQ35869.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Peptidase_S8 PF00082.22 EEQ35871.1 - 2.2e-34 119.1 5.6 4e-34 118.2 5.6 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ35871.1 - 5.7e-19 68.6 0.1 9.6e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 p450 PF00067.22 EEQ35873.1 - 1.2e-19 70.4 0.0 3.9e-16 58.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Zn_clus PF00172.18 EEQ35875.1 - 5.5e-06 26.4 8.6 1e-05 25.6 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EEQ35876.1 - 0.0065 15.4 5.9 0.015 14.2 5.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF202 PF02656.15 EEQ35876.1 - 0.092 13.2 4.1 1.9 9.0 1.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF202) TRI12 PF06609.13 EEQ35877.1 - 1.6e-06 26.8 9.6 3.7e-06 25.7 9.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EEQ35877.1 - 6.2e-06 25.4 19.1 0.00019 20.5 19.1 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ35877.1 - 0.0022 16.9 4.5 0.0022 16.9 4.5 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3522 PF12036.8 EEQ35877.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3522) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Arthroderma_otae_CBS113480-ASM15114v1/GCA_000151145.1_ASM15114v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Arthroderma_otae_CBS113480-ASM15114v1/GCA_000151145.1_ASM15114v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Arthroderma_otae_CBS113480-ASM15114v1/GCA_000151145.1_ASM15114v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Arthroderma_otae_CBS113480-ASM15114v1/GCA_000151145.1_ASM15114v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 13:48:07 2019 # [ok]