# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- APH PF01636.18 EEQ27113.1 - 9.9e-14 51.6 0.0 2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_3 PF13302.1 EEQ27114.1 - 1.3e-29 103.2 0.0 1.5e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ27114.1 - 0.00022 21.1 0.0 0.0047 16.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ27114.1 - 0.0074 16.2 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family BCNT PF07572.7 EEQ27115.1 - 5.2e-29 100.0 1.7 1.3e-28 98.7 1.2 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development Mis12 PF05859.7 EEQ27118.1 - 2e-36 124.9 0.0 3.3e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein APH PF01636.18 EEQ27119.1 - 4.2e-05 23.3 0.2 0.00013 21.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ27119.1 - 0.00023 20.7 0.1 0.00067 19.2 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase HSDR_N_2 PF13588.1 EEQ27119.1 - 0.00087 19.0 0.0 0.75 9.6 0.0 2.6 1 1 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Pkinase PF00069.20 EEQ27119.1 - 0.0024 17.0 0.1 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CENP-X PF09415.5 EEQ27120.1 - 3.4e-20 71.6 1.5 1e-19 70.1 1.0 1.8 1 1 0 1 1 1 1 CENP-S associating Centromere protein X DUF1373 PF07117.6 EEQ27120.1 - 0.047 13.4 1.0 0.061 13.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Ebola_NP PF05505.7 EEQ27120.1 - 0.069 11.2 6.3 0.068 11.2 4.4 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein DUF1525 PF07511.6 EEQ27120.1 - 0.26 11.2 3.3 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) CBFD_NFYB_HMF PF00808.18 EEQ27120.1 - 0.83 9.7 3.7 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pneumo_att_G PF05539.6 EEQ27120.1 - 1.4 8.1 9.1 1.6 8.0 6.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MRI PF15325.1 EEQ27120.1 - 4.1 8.4 8.2 10 7.1 5.7 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection Mnd1 PF03962.10 EEQ27120.1 - 4.9 6.7 9.1 7.8 6.1 6.2 1.5 1 1 0 1 1 1 0 Mnd1 family BRCA-2_helical PF09169.5 EEQ27120.1 - 7.6 6.0 7.0 22 4.5 1.5 2.1 1 1 1 2 2 2 0 BRCA2, helical Macro PF01661.16 EEQ27121.1 - 0.037 13.9 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Macro domain MIF PF01187.13 EEQ27122.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Telomere_Sde2_2 PF13297.1 EEQ27122.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal Dus PF01207.12 EEQ27123.1 - 1.3e-34 119.4 0.0 1e-30 106.6 0.0 2.6 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) Asn_synthase PF00733.16 EEQ27123.1 - 0.039 13.4 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Imm20 PF15568.1 EEQ27123.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 20 bZIP_1 PF00170.16 EEQ27124.1 - 6.9e-11 41.9 7.8 6.9e-11 41.9 5.4 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ27124.1 - 1.3e-05 24.9 9.7 1.3e-05 24.9 6.7 2.9 3 0 0 3 3 3 1 Basic region leucine zipper Methyltransf_18 PF12847.2 EEQ27125.1 - 6.4e-19 68.5 0.0 4.5e-17 62.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27125.1 - 9.6e-19 67.6 0.0 6.3e-15 55.4 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ27125.1 - 1.9e-18 66.6 0.0 2.2e-15 56.7 0.0 2.8 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ27125.1 - 3.6e-16 59.1 0.0 7.2e-14 51.6 0.0 2.9 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ27125.1 - 9.9e-16 57.9 0.0 1e-14 54.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ27125.1 - 9.4e-14 51.6 0.0 1.3e-09 38.4 0.0 2.7 3 0 0 3 3 2 2 Methyltransferase domain CMAS PF02353.15 EEQ27125.1 - 1.4e-10 40.7 0.0 2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EEQ27125.1 - 1.5e-09 37.9 0.1 5.4e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 EEQ27125.1 - 3.1e-05 23.2 0.0 5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 EEQ27125.1 - 0.00025 20.4 0.0 0.0066 15.8 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Pox_MCEL PF03291.11 EEQ27125.1 - 0.0013 17.7 0.0 0.068 12.0 0.0 2.2 1 1 0 1 1 1 1 mRNA capping enzyme MTS PF05175.9 EEQ27125.1 - 0.0014 17.9 0.0 0.0043 16.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EEQ27125.1 - 0.0034 16.5 0.0 0.0087 15.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 EEQ27125.1 - 0.0036 16.5 0.2 0.37 10.0 0.0 2.4 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain TPMT PF05724.6 EEQ27125.1 - 0.0092 15.4 0.0 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) UPF0146 PF03686.8 EEQ27125.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_2 PF00891.13 EEQ27125.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase PCMT PF01135.14 EEQ27125.1 - 0.017 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.7 EEQ27125.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase 3HCDH_N PF02737.13 EEQ27125.1 - 0.027 14.1 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RrnaAD PF00398.15 EEQ27125.1 - 0.068 12.1 0.0 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EEQ27125.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 EEQ27125.1 - 0.15 12.0 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 1 0 TrkA-N domain NAD_binding_10 PF13460.1 EEQ27126.1 - 4.6e-19 69.1 0.2 6.6e-19 68.6 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ27126.1 - 0.0057 16.1 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEQ27126.1 - 0.043 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Lactamase_B_2 PF12706.2 EEQ27127.1 - 1.8e-30 105.9 0.4 3.7e-30 104.9 0.3 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EEQ27127.1 - 3.1e-26 90.6 0.1 4.4e-25 86.9 0.0 2.8 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B PF00753.22 EEQ27127.1 - 1.7e-07 31.1 0.3 3.5e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily His_Phos_2 PF00328.17 EEQ27128.1 - 5.8e-21 75.1 0.0 8.9e-20 71.3 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Gtr1_RagA PF04670.7 EEQ27129.1 - 6.1e-53 179.3 1.2 8.9e-53 178.8 0.4 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EEQ27129.1 - 0.031 13.7 0.1 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.16 EEQ27129.1 - 0.036 13.3 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family Cyt-b5 PF00173.23 EEQ27130.1 - 4.9e-08 32.6 0.0 8.5e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S25 PF03297.10 EEQ27131.1 - 9.7e-40 134.8 4.9 1.1e-39 134.7 3.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 EEQ27131.1 - 0.0069 15.8 0.1 0.0095 15.4 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.2 EEQ27131.1 - 0.011 15.4 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.7 EEQ27131.1 - 0.022 14.3 0.1 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 HTH domain Rrf2 PF02082.15 EEQ27131.1 - 0.044 13.8 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.14 EEQ27131.1 - 0.062 13.0 0.3 0.082 12.6 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB GntR PF00392.16 EEQ27131.1 - 0.071 12.5 0.1 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family FeoC PF09012.5 EEQ27131.1 - 0.072 12.8 0.2 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 FeoC like transcriptional regulator WD40 PF00400.27 EEQ27132.1 - 1.2e-09 37.6 0.9 0.0071 16.2 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat IKI3 PF04762.7 EEQ27132.1 - 0.00011 20.2 0.0 0.00022 19.2 0.0 1.5 1 0 0 1 1 1 1 IKI3 family Apc4_WD40 PF12894.2 EEQ27132.1 - 0.09 12.2 0.0 3.1 7.3 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 EEQ27132.1 - 0.15 11.7 1.2 6.6 6.5 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat 2OG-FeII_Oxy_3 PF13640.1 EEQ27133.1 - 0.00061 20.2 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.22 EEQ27134.1 - 7.1e-08 32.8 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEQ27134.1 - 0.00028 20.9 0.0 0.00036 20.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEQ27134.1 - 0.00032 20.1 0.1 0.00032 20.1 0.0 1.6 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ27134.1 - 0.013 16.3 0.0 0.021 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEQ27134.1 - 0.013 15.1 0.0 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 EEQ27134.1 - 0.015 15.5 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EEQ27134.1 - 0.027 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EEQ27134.1 - 0.037 13.7 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EEQ27134.1 - 0.054 13.4 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEQ27134.1 - 0.066 12.6 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EEQ27134.1 - 0.066 12.1 0.1 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 EEQ27134.1 - 0.07 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEQ27134.1 - 0.074 13.0 0.1 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EEQ27134.1 - 0.083 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEQ27134.1 - 0.084 12.3 0.1 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EEQ27134.1 - 0.1 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA PF00004.24 EEQ27134.1 - 0.13 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EEQ27134.1 - 0.13 12.0 0.2 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 SMC_N PF02463.14 EEQ27134.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 EEQ27135.1 - 4e-24 85.4 0.0 6.8e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEQ27135.1 - 1e-07 32.2 1.3 0.0013 18.7 0.1 2.1 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EEQ27135.1 - 3.4e-05 23.1 0.1 0.023 13.9 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 EEQ27135.1 - 0.019 15.4 0.0 0.055 13.9 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EEQ27135.1 - 0.027 13.6 0.1 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EEQ27135.1 - 0.032 14.1 0.0 0.71 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EEQ27135.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EEQ27135.1 - 0.12 12.3 1.4 0.4 10.6 1.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AA_permease PF00324.16 EEQ27136.1 - 1.5e-138 462.1 39.5 1.8e-138 461.8 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ27136.1 - 1.3e-35 122.7 39.6 1.7e-35 122.4 27.4 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EEQ27136.1 - 0.06 11.8 0.1 0.095 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) MoaC PF01967.16 EEQ27137.1 - 5.2e-41 139.4 0.1 1.1e-40 138.4 0.0 1.5 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EEQ27137.1 - 1.9e-35 121.3 0.0 1.2e-34 118.7 0.0 2.1 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EEQ27137.1 - 8.5e-23 81.3 0.1 1.7e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EEQ27137.1 - 0.00033 20.7 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EEQ27137.1 - 0.00094 19.2 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Piwi PF02171.12 EEQ27138.1 - 7.8e-19 67.7 0.2 5.1e-10 38.8 0.0 2.3 1 1 1 2 2 2 2 Piwi domain PAZ PF02170.17 EEQ27138.1 - 2e-07 30.3 0.0 4.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 PAZ domain VPS28 PF03997.7 EEQ27140.1 - 2.8e-60 203.1 0.3 3.2e-60 202.9 0.2 1.0 1 0 0 1 1 1 1 VPS28 protein SPOB_a PF14689.1 EEQ27140.1 - 0.04 13.4 0.7 0.1 12.1 0.1 1.9 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain Imm3 PF14425.1 EEQ27140.1 - 0.097 12.6 0.7 3.2 7.7 0.1 2.4 2 1 0 2 2 2 0 Immunity protein Imm3 Methyltransf_16 PF10294.4 EEQ27141.1 - 6.5e-21 74.5 0.0 1.5e-20 73.3 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase APH PF01636.18 EEQ27142.1 - 7e-16 58.6 0.0 9.7e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Repressor_Mnt PF11423.3 EEQ27142.1 - 0.021 14.1 1.9 0.031 13.5 0.2 2.1 2 0 0 2 2 2 0 Regulatory protein Mnt Choline_kinase PF01633.15 EEQ27142.1 - 0.064 12.8 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PRTase_1 PF11202.3 EEQ27142.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) MFS_1 PF07690.11 EEQ27144.1 - 3e-30 105.1 93.2 6.9e-29 100.6 42.0 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ27144.1 - 2.8e-15 55.5 13.2 2.8e-15 55.5 9.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ27144.1 - 7.1e-10 38.0 7.8 7.1e-10 38.0 5.4 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter YrhK PF14145.1 EEQ27144.1 - 0.97 9.1 12.4 0.73 9.5 0.8 3.6 3 1 1 4 4 4 0 YrhK-like protein Pkinase PF00069.20 EEQ27145.1 - 4.2e-15 55.6 0.0 1.7e-07 30.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27145.1 - 1.9e-09 36.9 0.0 0.00012 21.3 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Tannase PF07519.6 EEQ27147.1 - 3e-76 257.0 0.2 2.7e-71 240.6 0.0 2.2 1 1 1 2 2 2 2 Tannase and feruloyl esterase Zn_clus PF00172.13 EEQ27147.1 - 1.2e-08 34.7 8.4 2.2e-08 33.8 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.15 EEQ27147.1 - 0.0036 16.8 0.0 0.0082 15.7 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ27147.1 - 0.0079 16.0 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family VWA PF00092.23 EEQ27148.1 - 1.6e-08 34.5 0.0 2.9e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EEQ27148.1 - 3.3e-07 30.5 0.1 5.4e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Apc4 PF12896.2 EEQ27150.1 - 2.7e-63 213.0 0.9 4.1e-63 212.4 0.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EEQ27150.1 - 3.2e-16 58.5 0.0 6.7e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT PF02985.17 EEQ27151.1 - 1.3e-16 59.1 10.2 0.00019 21.2 0.0 9.1 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.1 EEQ27151.1 - 2.6e-14 53.2 8.6 0.00016 21.8 0.0 6.2 4 1 2 6 6 6 4 HEAT repeats CLASP_N PF12348.3 EEQ27151.1 - 1.8e-08 34.0 2.9 0.002 17.5 0.0 4.5 4 2 1 5 5 5 2 CLASP N terminal HEAT_EZ PF13513.1 EEQ27151.1 - 3.8e-08 33.5 20.3 1.3e-05 25.5 0.0 8.4 8 2 3 11 11 11 2 HEAT-like repeat IBN_N PF03810.14 EEQ27151.1 - 1.8e-07 30.9 0.6 5.9e-05 22.9 0.0 3.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3535 PF12054.3 EEQ27151.1 - 0.00037 19.2 0.8 0.00084 18.0 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) Arm PF00514.18 EEQ27151.1 - 0.0011 18.7 2.9 22 5.0 0.1 5.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MMS19_N PF14500.1 EEQ27151.1 - 0.0017 17.6 0.1 1.2 8.3 0.2 2.8 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II Ribosomal_S8 PF00410.14 EEQ27152.1 - 4.2e-25 88.0 0.1 5.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DUF1995 PF09353.5 EEQ27152.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1995) His_Phos_1 PF00300.17 EEQ27153.1 - 3.3e-16 59.7 0.0 5.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PINIT PF14324.1 EEQ27153.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 PINIT domain ubiquitin PF00240.18 EEQ27154.1 - 1.3e-10 40.5 0.0 2.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EEQ27154.1 - 0.00047 20.3 0.8 0.00091 19.3 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EEQ27154.1 - 0.0061 16.4 0.0 0.031 14.1 0.0 2.2 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 EEQ27154.1 - 0.035 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PS_Dcarbxylase PF02666.10 EEQ27155.1 - 3e-81 271.5 0.0 5.9e-81 270.6 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase E1-E2_ATPase PF00122.15 EEQ27156.1 - 5.7e-52 176.0 1.5 9.5e-52 175.3 1.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ27156.1 - 1.8e-36 125.3 9.1 1.6e-35 122.2 4.2 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ27156.1 - 8.8e-32 111.2 0.0 5.1e-29 102.2 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ27156.1 - 2.5e-16 59.4 0.0 5e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ27156.1 - 1.2e-12 48.3 0.0 5.2e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ27156.1 - 5.1e-12 45.0 0.0 1.2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEQ27156.1 - 2.3e-05 24.1 0.1 0.004 16.7 0.2 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 EEQ27156.1 - 0.017 14.7 0.6 0.03 13.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) APC10 PF03256.11 EEQ27157.1 - 3.8e-42 144.0 0.0 6.5e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) RNA_pol_Rpc4 PF05132.9 EEQ27157.1 - 0.39 10.6 2.0 0.38 10.7 0.5 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Iso_dh PF00180.15 EEQ27158.1 - 4.7e-130 433.5 0.0 5.4e-130 433.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.20 EEQ27159.1 - 1e-27 96.9 0.0 2.4e-27 95.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27159.1 - 7.4e-14 51.4 0.2 1.7e-13 50.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PrgH PF09480.5 EEQ27159.1 - 0.0074 15.1 0.3 0.0098 14.7 0.2 1.1 1 0 0 1 1 1 1 Type III secretion system protein PrgH-EprH (PrgH) Methyltransf_23 PF13489.1 EEQ27161.1 - 9.4e-11 41.6 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27161.1 - 0.018 15.5 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ27161.1 - 0.091 13.2 0.0 0.43 11.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ27161.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CDP-OH_P_transf PF01066.16 EEQ27162.1 - 3.5e-17 62.5 6.9 6.8e-17 61.6 4.7 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.16 EEQ27163.1 - 2.1e-32 112.5 0.0 4.3e-26 91.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EEQ27163.1 - 0.0042 16.4 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C MscS_porin PF12795.2 EEQ27164.1 - 0.034 13.4 8.3 0.053 12.8 5.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4559 PF15112.1 EEQ27164.1 - 0.042 13.0 2.3 0.084 12.0 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Serglycin PF04360.7 EEQ27164.1 - 0.67 9.6 3.2 1.3 8.7 2.0 1.6 1 1 0 1 1 1 0 Serglycin RRM_1 PF00076.17 EEQ27165.1 - 1.4e-40 136.7 0.4 2e-18 65.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ27165.1 - 2.1e-32 110.9 0.1 1.5e-17 63.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EEQ27165.1 - 3.2e-30 104.1 1.0 8.1e-30 102.9 0.2 2.1 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EEQ27165.1 - 3.2e-22 78.1 0.0 4.3e-09 36.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEQ27165.1 - 0.028 14.2 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif MFS_1 PF07690.11 EEQ27166.1 - 2.9e-34 118.3 42.5 1.1e-32 113.1 28.6 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ27166.1 - 3.7e-11 42.2 14.6 3.7e-11 42.2 10.1 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter Cyt-b5 PF00173.23 EEQ27168.1 - 1.1e-18 66.7 0.6 1.5e-17 63.1 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EEQ27168.1 - 2e-07 31.4 20.7 2.7e-07 30.9 12.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EEQ27168.1 - 0.012 15.6 0.2 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region OMPdecase PF00215.19 EEQ27169.1 - 1.6e-07 30.9 0.0 8.3e-06 25.3 0.0 2.4 2 0 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Cu-oxidase_2 PF07731.9 EEQ27170.1 - 4.5e-46 155.7 6.4 3.3e-41 140.0 0.4 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EEQ27170.1 - 4.2e-42 142.5 5.0 1.6e-39 134.2 0.6 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EEQ27170.1 - 5.7e-36 123.8 0.2 3.1e-31 108.4 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EEQ27170.1 - 0.00092 19.0 0.0 3.7 7.4 0.0 3.4 2 1 0 2 2 2 2 Cupredoxin-like domain FTR1 PF03239.9 EEQ27171.1 - 4e-67 226.3 5.7 5.3e-67 225.9 4.0 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family PsaL PF02605.10 EEQ27171.1 - 0.033 13.7 0.8 0.19 11.2 0.0 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI ABC2_membrane_3 PF12698.2 EEQ27171.1 - 0.11 11.5 9.3 0.033 13.2 0.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF3353 PF11833.3 EEQ27171.1 - 0.66 9.4 6.8 0.074 12.4 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Adap_comp_sub PF00928.16 EEQ27173.1 - 2.3e-20 72.7 0.0 3.4e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEQ27173.1 - 1.1e-07 31.7 0.1 1.7e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EEQ27173.1 - 0.012 15.6 0.2 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.4 EEQ27174.1 - 0.00045 19.7 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.9 EEQ27175.1 - 2.3e-104 348.5 10.5 2.7e-104 348.3 7.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EEQ27175.1 - 2.8e-06 27.5 2.3 2.8e-06 27.5 1.6 3.2 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 EEQ27175.1 - 5.6e-05 23.1 29.6 9.4e-05 22.4 6.4 3.1 2 1 1 3 3 3 2 EamA-like transporter family DUF2937 PF11157.3 EEQ27175.1 - 0.26 10.5 1.0 0.75 9.1 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Syja_N PF02383.13 EEQ27176.1 - 9.4e-81 271.0 0.0 3.7e-62 209.9 0.0 2.4 1 1 1 2 2 2 2 SacI homology domain hSac2 PF12456.3 EEQ27176.1 - 6.5e-39 131.8 0.0 1.1e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase HEAT_EZ PF13513.1 EEQ27177.1 - 3.2e-29 100.6 7.0 4.9e-13 49.1 0.0 10.7 7 2 4 11 11 11 4 HEAT-like repeat HEAT PF02985.17 EEQ27177.1 - 1.5e-26 90.0 12.1 6.4e-05 22.6 0.0 10.9 12 0 0 12 12 11 4 HEAT repeat HEAT_2 PF13646.1 EEQ27177.1 - 5.1e-25 87.5 2.0 3.6e-09 36.7 0.0 8.7 3 3 5 8 8 8 5 HEAT repeats Cnd1 PF12717.2 EEQ27177.1 - 1e-10 41.7 0.0 0.00049 20.0 0.0 6.0 4 3 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EEQ27177.1 - 6.2e-10 39.3 0.0 0.0053 17.1 0.0 4.8 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EEQ27177.1 - 3.6e-08 33.0 1.3 0.0032 16.8 0.1 6.0 3 3 1 4 4 4 1 CLASP N terminal RIX1 PF08167.7 EEQ27177.1 - 2.3e-06 27.3 2.2 0.07 12.7 0.0 5.7 4 2 2 6 6 6 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EEQ27177.1 - 3e-06 26.2 2.4 1.2 7.8 0.0 4.8 4 2 1 5 5 5 2 RNAPII transcription regulator C-terminal Arm PF00514.18 EEQ27177.1 - 2.1e-05 24.1 0.3 1.7 8.5 0.0 6.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Xpo1 PF08389.7 EEQ27177.1 - 6.6e-05 22.8 1.7 0.0036 17.2 0.0 4.4 5 1 0 5 5 4 1 Exportin 1-like protein TIP120 PF08623.5 EEQ27177.1 - 0.00083 18.9 0.0 3.1 7.3 0.0 3.8 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) Sec7_N PF12783.2 EEQ27177.1 - 0.0049 16.3 0.2 0.016 14.6 0.1 1.9 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal IBN_N PF03810.14 EEQ27177.1 - 0.0077 16.1 0.7 0.21 11.5 0.1 3.6 3 1 0 3 3 3 1 Importin-beta N-terminal domain Dopey_N PF04118.9 EEQ27177.1 - 0.044 12.5 0.4 0.18 10.5 0.0 2.2 2 0 0 2 2 2 0 Dopey, N-terminal DUF3437 PF11919.3 EEQ27177.1 - 0.083 12.6 0.0 0.97 9.1 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF3437) ANAPC15 PF15243.1 EEQ27177.1 - 0.3 11.1 6.2 5.9 7.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 HEAT_PBS PF03130.11 EEQ27177.1 - 0.66 10.5 5.8 22 5.8 0.0 5.0 7 0 0 7 7 3 0 PBS lyase HEAT-like repeat Fungal_trans_2 PF11951.3 EEQ27179.1 - 1.5e-09 36.9 1.1 2.5e-09 36.2 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ27179.1 - 3.2e-07 30.1 15.5 5.9e-07 29.2 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C12 PF01088.16 EEQ27180.1 - 2.2e-70 236.1 0.0 3e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MFS_1 PF07690.11 EEQ27183.1 - 3.4e-30 104.9 29.3 5.1e-30 104.3 20.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2650 PF10853.3 EEQ27184.1 - 1.7 8.1 5.3 3.1 7.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Amidohydro_2 PF04909.9 EEQ27185.1 - 2.5e-09 37.1 0.4 1.7e-08 34.3 0.3 2.0 1 1 0 1 1 1 1 Amidohydrolase CitT PF12431.3 EEQ27185.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Fungal_trans PF04082.13 EEQ27186.1 - 2.4e-27 95.4 0.1 9.9e-27 93.4 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ27186.1 - 1.8e-09 37.3 9.4 3.5e-09 36.4 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4591 PF15261.1 EEQ27186.1 - 0.06 13.5 0.3 0.16 12.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) tRNA-synt_2b PF00587.20 EEQ27187.1 - 1.2e-47 161.7 0.0 1.6e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ27187.1 - 1.1e-05 25.2 0.0 8e-05 22.5 0.0 2.3 3 0 0 3 3 3 1 Anticodon binding domain ECH PF00378.15 EEQ27188.1 - 4.6e-35 120.9 0.0 5.5e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pyr_redox_2 PF07992.9 EEQ27189.1 - 2.7e-37 128.6 0.5 3.6e-37 128.1 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EEQ27189.1 - 6.3e-32 109.8 0.1 1.3e-31 108.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EEQ27189.1 - 6.3e-13 48.9 0.1 6.3e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ27189.1 - 0.00033 20.7 0.0 0.0025 17.8 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEQ27189.1 - 0.037 13.6 0.1 0.085 12.5 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EEQ27189.1 - 0.53 9.0 3.6 0.61 8.8 0.3 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Ank_2 PF12796.2 EEQ27191.1 - 2.1e-06 28.0 0.0 3.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ27191.1 - 3.8e-05 24.0 0.0 8.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EEQ27191.1 - 0.00031 20.3 0.1 0.018 14.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EEQ27191.1 - 0.0013 18.9 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ27191.1 - 0.0035 17.4 0.0 0.45 10.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat CDC45 PF02724.9 EEQ27191.1 - 0.0095 14.0 2.2 0.011 13.7 1.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 EEQ27191.1 - 0.017 13.0 8.0 0.02 12.8 5.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EEQ27191.1 - 0.12 11.6 10.7 0.17 11.1 7.4 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.8 EEQ27191.1 - 0.24 10.9 9.8 0.37 10.3 6.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF2457 PF10446.4 EEQ27191.1 - 0.99 8.0 17.9 1.5 7.4 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EEQ27191.1 - 10 5.7 11.0 18 4.8 7.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region MFS_1 PF07690.11 EEQ27192.1 - 3.7e-46 157.4 39.2 6.9e-46 156.5 27.2 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ27192.1 - 7.9e-17 60.9 24.4 1.8e-16 59.7 9.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EEQ27192.1 - 8e-16 57.3 14.7 8e-16 57.3 10.2 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Peptidase_C37 PF05416.7 EEQ27192.1 - 0.21 9.8 0.4 0.47 8.6 0.0 1.6 2 0 0 2 2 2 0 Southampton virus-type processing peptidase DUF3419 PF11899.3 EEQ27194.1 - 9.9e-151 501.7 0.4 1.4e-150 501.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EEQ27194.1 - 7e-11 42.0 0.0 3.3e-09 36.6 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ27194.1 - 2.1e-08 34.6 0.0 8.3e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ27194.1 - 8.5e-08 31.9 0.0 3.7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ27194.1 - 3.5e-06 27.0 0.0 0.00019 21.4 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ27194.1 - 5.1e-06 26.8 0.0 1.9e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ27194.1 - 1.8e-05 24.9 0.0 6.3e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27194.1 - 2.7e-05 24.5 0.0 0.0015 18.9 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ27194.1 - 9.9e-05 21.4 0.1 0.0014 17.7 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EEQ27194.1 - 0.00039 20.0 0.0 0.00088 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EEQ27194.1 - 0.00097 18.3 0.0 0.0025 16.9 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EEQ27194.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 EEQ27194.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Vps54 PF07928.7 EEQ27196.1 - 7.2e-25 87.6 0.1 2.7e-24 85.8 0.1 2.0 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EEQ27196.1 - 0.0015 17.4 0.2 0.0015 17.4 0.1 2.0 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EEQ27196.1 - 0.052 13.4 0.3 0.41 10.5 0.1 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Solute_trans_a PF03619.11 EEQ27197.1 - 5.7e-43 147.1 7.1 8.5e-43 146.6 5.0 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha YycC PF14174.1 EEQ27197.1 - 0.034 13.8 0.9 0.1 12.2 0.1 2.0 2 0 0 2 2 2 0 YycC-like protein Peptidase_M15_3 PF08291.6 EEQ27198.1 - 0.023 14.4 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase M15 Pkinase PF00069.20 EEQ27199.1 - 2.6e-49 167.7 0.0 4.4e-47 160.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27199.1 - 6.8e-32 110.5 0.0 9.1e-31 106.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ27199.1 - 0.00027 19.9 0.0 0.00045 19.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EEQ27199.1 - 0.0013 17.6 0.1 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EEQ27199.1 - 0.035 12.9 0.0 0.052 12.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EEQ27200.1 - 6.3e-10 39.1 0.0 1.5e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Mem_trans PF03547.13 EEQ27201.1 - 1.5e-53 181.4 2.2 1.8e-53 181.2 1.5 1.1 1 0 0 1 1 1 1 Membrane transport protein Choline_kinase PF01633.15 EEQ27202.1 - 5.3e-35 120.9 0.0 9.8e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EEQ27202.1 - 2.7e-15 55.5 0.0 8.4e-15 53.9 0.0 1.9 1 0 0 1 1 1 1 Choline kinase N terminus Abhydrolase_2 PF02230.11 EEQ27203.1 - 2e-25 89.4 0.0 2.3e-17 63.1 0.0 2.1 1 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEQ27203.1 - 4.3e-08 33.3 0.5 2.5e-07 30.8 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ27203.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ27203.1 - 0.0014 17.8 0.2 0.0036 16.5 0.1 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 EEQ27203.1 - 0.0044 16.4 0.0 0.0089 15.4 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.9 EEQ27203.1 - 0.2 10.8 0.4 0.3 10.2 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase Glyco_hydro_31 PF01055.21 EEQ27204.1 - 3.8e-183 609.3 1.0 4.6e-183 609.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEQ27204.1 - 2.1e-11 43.5 0.3 7.3e-11 41.7 0.2 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like ANAPC15 PF15243.1 EEQ27205.1 - 0.015 15.3 2.6 0.041 13.9 1.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Nucleoplasmin PF03066.10 EEQ27205.1 - 0.047 13.1 1.3 0.069 12.6 0.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EEQ27205.1 - 0.11 11.6 2.5 0.16 11.1 1.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Asp PF00026.18 EEQ27206.1 - 6.7e-07 28.8 1.1 8.6e-06 25.2 0.7 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease IncA PF04156.9 EEQ27206.1 - 0.042 13.4 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 IncA protein SKG6 PF08693.5 EEQ27206.1 - 0.056 12.7 0.1 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EEQ27206.1 - 0.077 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MFS_1 PF07690.11 EEQ27207.1 - 1.3e-17 63.6 40.3 1.8e-12 46.6 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ27207.1 - 2.9e-16 59.1 22.8 5.9e-16 58.0 15.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_92 PF07971.7 EEQ27208.1 - 7e-144 480.1 0.4 6e-93 312.1 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 M157 PF11624.3 EEQ27208.1 - 0.068 12.2 0.2 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 ATP-synt_G PF04718.10 EEQ27210.1 - 7.1e-29 100.4 0.0 3e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_zinc_N PF00107.21 EEQ27211.1 - 6.2e-18 64.5 0.0 1.3e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ27211.1 - 1.4e-13 51.8 0.0 4.5e-13 50.2 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ27211.1 - 1.5e-08 34.3 0.2 7.3e-08 32.1 0.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain TraI_2 PF07514.6 EEQ27211.1 - 0.048 12.4 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative helicase APH PF01636.18 EEQ27212.1 - 7.6e-12 45.4 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ27212.1 - 2.3e-06 27.3 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ27212.1 - 0.01 15.2 0.1 0.02 14.2 0.0 1.6 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 EEQ27212.1 - 0.037 13.1 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HECA PF15353.1 EEQ27212.1 - 0.078 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Headcase protein family homologue EcKinase PF02958.15 EEQ27212.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Abhydrolase_1 PF00561.15 EEQ27213.1 - 1.3e-14 54.3 0.0 2.9e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ27213.1 - 1.8e-11 44.3 0.0 3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAP_central PF04928.12 EEQ27214.1 - 3.7e-102 340.4 0.0 5.2e-102 339.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EEQ27214.1 - 3.2e-46 156.7 0.0 6.4e-46 155.7 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EEQ27214.1 - 0.00019 21.6 0.5 0.015 15.6 0.3 2.5 1 1 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EEQ27214.1 - 0.1 10.1 0.0 0.17 9.4 0.0 1.2 1 0 0 1 1 1 0 Nrap protein Glyco_transf_20 PF00982.16 EEQ27215.1 - 5.3e-153 509.9 0.0 7.1e-152 506.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EEQ27215.1 - 0.00038 19.9 0.1 0.0036 16.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEQ27215.1 - 0.00041 20.5 0.1 0.0011 19.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EEQ27215.1 - 0.0088 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain adh_short PF00106.20 EEQ27216.1 - 2e-26 92.8 3.1 3.1e-26 92.2 2.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ27216.1 - 6.3e-23 81.7 1.5 1.1e-22 81.0 1.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ27216.1 - 2.4e-12 46.8 1.2 4e-12 46.1 0.8 1.3 1 0 0 1 1 1 1 KR domain Poxvirus_B22R_C PF13168.1 EEQ27216.1 - 0.042 13.1 0.0 0.086 12.0 0.0 1.6 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal ACC_epsilon PF13822.1 EEQ27216.1 - 0.1 12.9 0.2 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Amidase PF01425.16 EEQ27217.1 - 1.3e-80 271.4 0.0 1.6e-80 271.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Cation_efflux PF01545.16 EEQ27218.1 - 1.3e-29 103.1 3.7 1.7e-29 102.8 2.5 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2834 PF11196.3 EEQ27218.1 - 0.0049 17.0 0.5 0.0049 17.0 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2834) DUF1772 PF08592.6 EEQ27218.1 - 0.064 12.9 0.1 0.19 11.4 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) MnhB PF04039.8 EEQ27218.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.6 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter FlgN PF05130.7 EEQ27218.1 - 0.21 11.8 2.2 0.48 10.6 1.5 1.5 1 0 0 1 1 1 0 FlgN protein Sulfotransfer_3 PF13469.1 EEQ27219.1 - 0.002 19.0 0.2 0.0029 18.5 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase family 2_5_RNA_ligase2 PF13563.1 EEQ27220.1 - 2.5e-30 105.2 0.0 5.3e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EEQ27220.1 - 8.3e-25 87.0 0.0 1.4e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain DUF504 PF04457.7 EEQ27220.1 - 1.1e-12 47.8 0.5 2.2e-12 46.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF504) Exo_endo_phos PF03372.18 EEQ27220.1 - 1.2e-12 48.3 0.1 2.2e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.18 EEQ27220.1 - 4.7e-05 23.6 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EEQ27220.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase LigT_PEase PF02834.11 EEQ27220.1 - 0.005 16.7 0.0 0.031 14.2 0.0 2.3 2 0 0 2 2 2 1 LigT like Phosphoesterase GATA PF00320.22 EEQ27224.1 - 7.7e-15 53.9 5.2 1.7e-14 52.8 3.6 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EEQ27224.1 - 0.21 11.5 1.9 0.53 10.3 1.3 1.7 1 0 0 1 1 1 0 zinc-finger Macro PF01661.16 EEQ27225.1 - 1.6e-34 118.3 0.0 3.4e-34 117.2 0.0 1.6 2 0 0 2 2 2 1 Macro domain Ank_2 PF12796.2 EEQ27226.1 - 4.2e-09 36.6 0.0 5.1e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ27226.1 - 3.6e-08 32.8 0.3 0.001 18.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EEQ27226.1 - 3.4e-06 27.1 1.2 0.0006 19.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ27226.1 - 5.7e-06 26.6 0.2 1.5e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ27226.1 - 3.7e-05 23.5 0.2 0.26 11.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat HTH_7 PF02796.10 EEQ27226.1 - 0.046 13.5 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Peptidase_S24 PF00717.18 EEQ27227.1 - 0.00014 21.4 0.1 0.00067 19.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EEQ27227.1 - 0.015 14.8 0.0 0.74 9.3 0.0 2.5 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 GLTP PF08718.6 EEQ27229.1 - 2.6e-38 131.3 0.1 3.6e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) AA_permease_2 PF13520.1 EEQ27230.1 - 1.9e-59 201.2 50.8 2.4e-59 200.9 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ27230.1 - 4.1e-22 78.1 38.0 6.1e-22 77.6 26.4 1.2 1 0 0 1 1 1 1 Amino acid permease Tmemb_18A PF09771.4 EEQ27230.1 - 3.6 7.5 7.1 11 5.9 0.1 3.4 3 0 0 3 3 3 0 Transmembrane protein 188 E1-E2_ATPase PF00122.15 EEQ27232.1 - 5.3e-23 81.2 0.0 4.7e-22 78.1 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ27232.1 - 3.5e-22 79.8 0.0 1.4e-21 77.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ27232.1 - 1.9e-18 67.3 0.0 3.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ27232.1 - 0.00039 20.3 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ27232.1 - 0.00048 19.7 0.2 0.0041 16.7 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EEQ27232.1 - 0.0067 15.7 0.4 0.22 10.8 0.0 2.6 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Cation_ATPase_N PF00690.21 EEQ27232.1 - 0.035 13.5 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus FYVE PF01363.16 EEQ27233.1 - 8.1e-23 80.1 23.8 8.7e-17 60.7 3.6 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 EEQ27233.1 - 0.0041 17.2 9.9 0.077 13.1 0.0 3.1 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Seryl_tRNA_N PF02403.17 EEQ27233.1 - 0.033 14.2 1.4 0.097 12.6 1.0 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IBR PF01485.16 EEQ27233.1 - 0.092 12.6 14.3 0.039 13.8 1.6 3.6 3 0 0 3 3 3 0 IBR domain zf-AN1 PF01428.11 EEQ27233.1 - 0.35 10.7 23.5 0.047 13.5 4.6 3.5 3 1 1 4 4 4 0 AN1-like Zinc finger FYVE_2 PF02318.11 EEQ27233.1 - 2.9 7.8 14.9 0.3 10.9 0.8 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger PKD_channel PF08016.7 EEQ27234.1 - 0.05 12.0 15.2 0.053 11.9 7.0 2.7 2 1 0 2 2 2 0 Polycystin cation channel CAML PF14963.1 EEQ27234.1 - 0.67 9.2 5.4 0.17 11.2 1.5 1.6 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand EIF_2_alpha PF07541.7 EEQ27235.1 - 2.2e-37 127.2 0.1 4.8e-37 126.1 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EEQ27235.1 - 2.5e-13 49.8 0.9 4.8e-13 48.9 0.6 1.4 1 0 0 1 1 1 1 S1 RNA binding domain SPOC PF07744.8 EEQ27235.1 - 0.13 12.7 0.0 0.66 10.4 0.0 2.0 2 0 0 2 2 2 0 SPOC domain Sulfate_transp PF00916.15 EEQ27236.1 - 5.8e-47 160.0 6.0 5.8e-47 160.0 4.2 1.6 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EEQ27236.1 - 8e-28 95.9 2.9 3.7e-27 93.8 2.0 2.3 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EEQ27236.1 - 2.5e-15 55.9 0.0 4.1e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EEQ27236.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 STAS domain CENP-L PF13092.1 EEQ27237.1 - 2.3e-60 203.0 0.0 2.9e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 DUF1470 PF07336.6 EEQ27237.1 - 0.11 12.7 0.0 0.86 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) DUF3638 PF12340.3 EEQ27238.1 - 2e-89 298.5 0.0 3.4e-89 297.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EEQ27238.1 - 2.5e-14 52.0 0.0 6.5e-14 50.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) ThiW PF09512.5 EEQ27238.1 - 1.5 8.6 0.0 2.9 7.7 0.0 1.3 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) Acetyltransf_1 PF00583.19 EEQ27239.1 - 5.1e-09 36.0 0.0 9.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ27239.1 - 1.7e-06 28.0 0.1 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ27239.1 - 0.0028 17.7 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EEQ27239.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Palm_thioest PF02089.10 EEQ27240.1 - 8.4e-65 218.4 0.0 1.1e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 EEQ27240.1 - 0.003 17.4 0.0 0.0036 17.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EEQ27240.1 - 0.016 14.5 0.0 0.059 12.6 0.0 2.1 1 1 0 1 1 1 0 Lipase (class 2) DUF915 PF06028.6 EEQ27240.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 EEQ27240.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold HTH_18 PF12833.2 EEQ27240.1 - 0.059 13.4 0.0 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain EF-hand_like PF09279.6 EEQ27240.1 - 0.066 13.2 1.8 0.33 10.9 0.2 2.4 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Trypan_PARP PF05887.6 EEQ27242.1 - 6.3 6.6 21.0 13 5.6 14.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DEC-1_N PF04625.8 EEQ27242.1 - 7.2 5.1 8.2 10 4.6 5.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF3328 PF11807.3 EEQ27243.1 - 6.3e-45 153.5 0.2 8.8e-45 153.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) zf-C2H2 PF00096.21 EEQ27244.1 - 0.47 10.9 6.4 3.3 8.2 0.1 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.5 EEQ27245.1 - 5e-64 216.1 0.0 2.2e-63 214.0 0.0 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EEQ27245.1 - 0.013 15.3 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain Atg8 PF02991.11 EEQ27246.1 - 3.3e-37 126.6 0.0 3.8e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EEQ27246.1 - 0.0015 18.6 0.0 0.0019 18.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Peptidase_S10 PF00450.17 EEQ27247.1 - 5.2e-90 302.5 0.1 6.4e-90 302.2 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Methyltransf_16 PF10294.4 EEQ27248.1 - 2.9e-15 56.1 0.0 4.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EEQ27248.1 - 5.1e-05 23.0 0.0 8.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ27248.1 - 0.0095 16.5 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EEQ27248.1 - 0.019 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family GidB PF02527.10 EEQ27248.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Antimicrobial_1 PF08018.6 EEQ27248.1 - 0.17 11.7 0.9 0.71 9.8 0.3 2.1 2 0 0 2 2 2 0 Frog antimicrobial peptide CASP_C PF08172.7 EEQ27249.1 - 0.048 12.6 2.2 0.071 12.1 1.5 1.3 1 1 0 1 1 1 0 CASP C terminal MFS_1 PF07690.11 EEQ27250.1 - 2.6e-39 134.9 35.8 7.2e-37 126.9 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ27250.1 - 9.5e-07 27.7 12.2 9.5e-07 27.7 8.4 3.1 2 2 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EEQ27250.1 - 0.0025 16.0 2.4 0.0025 16.0 1.7 2.3 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.1 EEQ27250.1 - 0.0028 16.1 1.6 0.0028 16.1 1.1 3.1 4 0 0 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.2 EEQ27250.1 - 0.014 15.1 3.6 0.034 13.9 0.2 3.3 4 0 0 4 4 4 0 MFS_1 like family F-box PF00646.28 EEQ27252.1 - 3.9e-05 23.1 0.1 0.00014 21.4 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EEQ27252.1 - 0.0053 16.4 0.2 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 F-box-like AlaDh_PNT_N PF05222.10 EEQ27253.1 - 3.9e-27 94.8 0.0 6.2e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EEQ27253.1 - 7.9e-07 28.7 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAR PF03114.13 EEQ27254.1 - 5.4e-64 215.8 7.3 6.7e-64 215.5 5.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EEQ27254.1 - 6.9e-13 47.7 0.0 1.4e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ27254.1 - 2.6e-12 46.1 0.0 4.5e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ27254.1 - 1.4e-08 34.0 0.0 3.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EEQ27254.1 - 0.037 13.2 7.1 0.48 9.6 0.0 2.2 2 0 0 2 2 2 0 Vps5 C terminal like TMPIT PF07851.8 EEQ27254.1 - 2.8 6.9 6.2 0.39 9.7 0.5 1.9 1 1 1 2 2 2 0 TMPIT-like protein Asp PF00026.18 EEQ27256.1 - 4.1e-55 187.2 7.2 2.5e-54 184.6 5.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEQ27256.1 - 3.1e-05 23.5 0.0 6.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EEQ27256.1 - 0.00067 20.1 0.8 0.36 11.3 0.2 2.8 2 0 0 2 2 2 2 Aspartyl protease AvrPphF-ORF-2 PF09143.5 EEQ27256.1 - 0.038 13.7 0.1 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 AvrPphF-ORF-2 APH PF01636.18 EEQ27257.1 - 1.7e-14 54.1 0.3 6.3e-14 52.2 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEQ27257.1 - 0.0012 17.8 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase GST_N_3 PF13417.1 EEQ27258.1 - 7e-18 64.6 0.0 1.3e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEQ27258.1 - 1.9e-16 59.9 0.1 5.3e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ27258.1 - 3.1e-12 46.3 0.0 4.2e-12 45.8 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEQ27258.1 - 7.3e-12 45.1 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ27258.1 - 0.00023 21.0 0.0 0.00052 19.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ27258.1 - 0.00033 21.0 0.0 0.00049 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ERG4_ERG24 PF01222.12 EEQ27259.1 - 2.3e-73 247.2 14.6 2.6e-46 158.0 4.9 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EEQ27259.1 - 0.012 14.9 1.9 0.014 14.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Pyridoxal_deC PF00282.14 EEQ27259.1 - 0.1 10.9 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain NB-ARC PF00931.17 EEQ27260.1 - 8.8e-12 44.4 0.0 1.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EEQ27260.1 - 4.1e-05 23.7 0.0 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ27260.1 - 0.00069 19.6 0.0 0.0025 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EEQ27260.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase ATP_transf PF09830.4 EEQ27261.1 - 3.7e-13 49.0 0.0 8.1e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase LEA_6 PF10714.4 EEQ27262.1 - 0.0004 20.1 3.8 0.00066 19.4 2.6 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein 18 MGC-24 PF05283.6 EEQ27262.1 - 0.00041 20.1 2.8 0.00058 19.7 2.0 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Copper-bind PF00127.15 EEQ27262.1 - 0.0011 19.1 0.1 0.0022 18.2 0.1 1.5 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family DX PF01666.12 EEQ27262.1 - 0.025 15.0 0.1 0.044 14.2 0.1 1.4 1 0 0 1 1 1 0 DX module Cupredoxin_1 PF13473.1 EEQ27262.1 - 0.046 13.6 0.3 0.27 11.1 0.2 2.0 1 1 0 1 1 1 0 Cupredoxin-like domain CDK2AP PF09806.4 EEQ27262.1 - 0.11 12.6 0.7 0.15 12.2 0.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Aminotran_5 PF00266.14 EEQ27263.1 - 7.1e-96 321.1 0.0 8.5e-96 320.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEQ27263.1 - 2.4e-08 33.5 0.0 3.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEQ27263.1 - 5.8e-06 25.5 0.0 1.9e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EEQ27263.1 - 0.018 13.4 0.0 0.026 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EEQ27263.1 - 0.08 11.2 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.13 EEQ27264.1 - 3.2e-155 516.7 0.0 3.7e-155 516.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Med2 PF11214.3 EEQ27264.1 - 0.11 12.5 0.1 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 2 UEV PF05743.8 EEQ27265.1 - 1.4e-36 124.8 0.0 2.3e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EEQ27265.1 - 1.9e-20 72.2 0.4 1.5e-19 69.3 0.0 2.3 2 0 0 2 2 2 1 Vps23 core domain CENP-Q PF13094.1 EEQ27265.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EEQ27265.1 - 0.0025 17.7 2.0 0.0042 16.9 1.4 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Halo_GVPC PF05465.8 EEQ27265.1 - 0.036 13.9 0.4 0.081 12.8 0.3 1.6 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat UQ_con PF00179.21 EEQ27265.1 - 0.045 13.1 0.8 0.12 11.7 0.1 2.1 3 0 0 3 3 3 0 Ubiquitin-conjugating enzyme Snapin_Pallidin PF14712.1 EEQ27265.1 - 0.065 13.5 0.8 0.1 12.8 0.6 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Reo_sigmaC PF04582.7 EEQ27265.1 - 0.097 11.8 5.6 0.15 11.2 3.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ACOX PF01756.14 EEQ27265.1 - 0.38 10.1 1.8 4.9 6.4 0.9 2.2 2 0 0 2 2 2 0 Acyl-CoA oxidase STE2 PF02116.10 EEQ27266.1 - 3.6e-84 282.1 24.2 4.4e-84 281.8 16.8 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Kdo PF06293.9 EEQ27267.1 - 1e-08 34.5 0.0 0.00016 20.8 0.0 3.0 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEQ27267.1 - 1.9e-08 33.7 0.0 2.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ27267.1 - 4.2e-07 29.9 0.0 0.00061 19.5 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EEQ27267.1 - 0.0026 16.8 0.0 0.0054 15.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ27267.1 - 0.0036 16.6 0.0 0.069 12.4 0.0 2.5 3 0 0 3 3 3 1 RIO1 family Choline_kinase PF01633.15 EEQ27267.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase SRP9-21 PF05486.7 EEQ27267.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) DUF1679 PF07914.6 EEQ27267.1 - 0.035 12.7 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEQ27267.1 - 0.085 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Aldo_ket_red PF00248.16 EEQ27268.1 - 3.3e-15 55.6 0.0 4.5e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 EEQ27269.1 - 6.7e-53 178.2 1.9 8.1e-53 177.9 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.6 EEQ27269.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Maf1 PF09174.5 EEQ27270.1 - 1.3e-62 210.8 0.0 1.9e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator Filament PF00038.16 EEQ27271.1 - 0.00046 19.7 18.5 0.00046 19.7 12.8 3.9 1 1 2 3 3 3 1 Intermediate filament protein IncA PF04156.9 EEQ27271.1 - 0.0013 18.4 19.3 0.0013 18.4 13.4 4.2 2 1 2 4 4 4 2 IncA protein Tropomyosin_1 PF12718.2 EEQ27271.1 - 0.0062 16.3 25.5 0.0062 16.3 17.7 4.6 3 1 1 4 4 4 2 Tropomyosin like NPV_P10 PF05531.7 EEQ27271.1 - 0.074 13.3 12.6 0.4 10.9 0.9 4.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Trypan_PARP PF05887.6 EEQ27271.1 - 0.17 11.6 24.3 0.6 9.9 16.8 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TSC22 PF01166.13 EEQ27271.1 - 0.22 11.5 0.1 0.22 11.5 0.1 4.8 4 1 1 5 5 5 0 TSC-22/dip/bun family Reo_sigmaC PF04582.7 EEQ27271.1 - 0.86 8.7 18.8 0.36 9.9 4.2 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EEQ27271.1 - 1.1 9.1 23.7 10 6.1 0.2 6.0 4 1 0 5 5 5 0 Flagella accessory protein C (FlaC) N2227 PF07942.7 EEQ27272.1 - 1.8e-64 217.3 0.0 2.7e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EEQ27272.1 - 0.0023 17.6 0.0 0.0058 16.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EEQ27274.1 - 1.2e-26 94.0 0.0 1.5e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ27274.1 - 1.9e-08 34.1 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEQ27274.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EEQ27274.1 - 0.025 13.4 0.0 0.16 10.7 0.0 2.1 1 1 1 2 2 2 0 Chlorophyllase PGAP1 PF07819.8 EEQ27274.1 - 0.044 13.3 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.2 EEQ27274.1 - 0.087 11.6 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme COPIIcoated_ERV PF07970.7 EEQ27275.1 - 1.7e-32 112.8 0.1 3.5e-31 108.5 0.1 2.3 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EEQ27275.1 - 8.4e-24 83.3 0.0 1.5e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.20 EEQ27276.1 - 3.3e-56 190.3 0.0 5.9e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27276.1 - 2.1e-19 69.6 0.0 4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ27276.1 - 0.29 10.4 0.1 0.53 9.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pex24p PF06398.6 EEQ27277.1 - 4.9e-84 282.1 0.3 5.9e-84 281.9 0.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 EEQ27277.1 - 0.0057 14.5 0.1 0.0083 14.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) FMO-like PF00743.14 EEQ27278.1 - 0.13 10.4 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Nop16 PF09420.5 EEQ27280.1 - 9.6e-58 194.8 13.0 1.1e-57 194.6 9.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.17 EEQ27281.1 - 1.5e-60 204.8 10.9 4.6e-60 203.2 7.6 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.9 EEQ27282.1 - 9.1e-101 336.5 0.0 1.5e-100 335.8 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EEQ27282.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mito_carr PF00153.22 EEQ27283.1 - 2.8e-49 164.7 0.2 5.8e-16 57.9 0.0 3.3 4 0 0 4 4 4 3 Mitochondrial carrier protein DUF3645 PF12359.3 EEQ27283.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) Ank_2 PF12796.2 EEQ27286.1 - 6.1e-83 273.2 16.5 1.9e-17 63.3 0.1 7.2 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ27286.1 - 1.2e-61 203.2 21.0 2e-13 50.1 0.0 12.4 3 2 10 13 13 13 13 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ27286.1 - 2.1e-58 193.7 23.6 9.5e-10 38.7 0.2 13.5 2 2 13 15 15 15 14 Ankyrin repeats (many copies) Ank PF00023.25 EEQ27286.1 - 1.6e-56 185.4 24.8 3.6e-09 35.9 0.0 14.7 14 0 0 14 14 14 13 Ankyrin repeat Ank_3 PF13606.1 EEQ27286.1 - 1.6e-44 145.4 14.6 2.5e-05 24.0 0.0 14.5 14 0 0 14 14 14 11 Ankyrin repeat F-box PF00646.28 EEQ27286.1 - 0.0026 17.3 0.5 0.02 14.5 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EEQ27286.1 - 0.11 12.2 0.7 0.26 11.0 0.5 1.7 1 0 0 1 1 1 0 F-box-like p450 PF00067.17 EEQ27287.1 - 3e-07 29.3 1.3 7.2e-07 28.0 0.4 1.9 2 1 0 2 2 2 1 Cytochrome P450 Chorismate_bind PF00425.13 EEQ27288.1 - 1.2e-83 280.3 0.0 2.2e-83 279.5 0.0 1.4 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 EEQ27288.1 - 6.5e-36 123.5 0.0 9.7e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EEQ27288.1 - 3.5e-11 43.3 0.0 8.5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EEQ27288.1 - 8.2e-08 31.9 0.1 2.2e-07 30.5 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 MFS_1 PF07690.11 EEQ27289.1 - 5.6e-32 110.8 26.8 9.4e-32 110.0 18.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MTBP_C PF14920.1 EEQ27290.1 - 0.039 13.4 0.2 0.083 12.3 0.2 1.4 1 0 0 1 1 1 0 MDM2-binding DUF1771 PF08590.5 EEQ27290.1 - 0.12 12.3 6.5 0.43 10.6 2.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1771) FH2 PF02181.18 EEQ27290.1 - 0.48 9.2 2.4 0.87 8.4 1.7 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain DHDPS PF00701.17 EEQ27291.1 - 4.3e-45 153.5 0.0 5.2e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2014 PF09427.5 EEQ27292.1 - 4.4e-102 340.6 0.2 6.5e-102 340.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EEQ27292.1 - 2.7e-18 65.3 1.4 6.9e-18 64.0 1.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain E1-E2_ATPase PF00122.15 EEQ27293.1 - 3.1e-64 216.1 6.6 6.3e-64 215.1 4.6 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ27293.1 - 3.6e-31 108.0 4.4 3.6e-31 108.0 3.1 2.5 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ27293.1 - 4.4e-26 92.6 0.1 1.6e-24 87.5 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ27293.1 - 1.9e-17 62.4 0.1 1.7e-16 59.4 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEQ27293.1 - 3e-12 47.1 0.0 1.3e-11 45.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ27293.1 - 9.4e-12 44.7 0.0 1.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ27293.1 - 1.5e-05 24.7 1.7 1.5e-05 24.7 1.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNase_PH_C PF03725.10 EEQ27295.1 - 0.018 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 RNase_PH PF01138.16 EEQ27295.1 - 0.049 13.9 0.2 0.14 12.5 0.1 1.8 2 1 0 2 2 2 0 3' exoribonuclease family, domain 1 Pro-kuma_activ PF09286.6 EEQ27296.1 - 2.6e-35 121.5 0.0 4.4e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEQ27296.1 - 1.8e-10 40.4 0.2 3e-10 39.7 0.2 1.4 1 1 0 1 1 1 1 Subtilase family NAD_kinase PF01513.16 EEQ27297.1 - 5e-66 222.3 0.0 2e-65 220.4 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase DAO PF01266.19 EEQ27298.1 - 1.4e-45 155.7 0.0 2.1e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEQ27298.1 - 0.0014 18.7 0.0 0.17 11.9 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ27298.1 - 0.0064 15.4 0.0 0.32 9.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEQ27298.1 - 0.026 14.3 0.0 1.6 8.4 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEQ27298.1 - 0.031 14.3 0.4 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GAF_2 PF13185.1 EEQ27299.1 - 1.7e-07 31.8 0.0 2e-07 31.6 0.0 1.0 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EEQ27299.1 - 1.8e-06 28.1 0.0 2.3e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EEQ27299.1 - 0.00033 20.7 0.0 0.00037 20.6 0.0 1.1 1 0 0 1 1 1 1 GAF domain DEAD PF00270.24 EEQ27300.1 - 2e-33 115.2 0.4 5.1e-32 110.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ27300.1 - 4.1e-22 77.8 0.2 9.6e-22 76.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEQ27300.1 - 0.14 12.3 0.5 0.62 10.1 0.2 2.2 2 1 0 2 2 2 0 AAA domain SH3_9 PF14604.1 EEQ27301.1 - 3.3e-26 90.6 0.6 3e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EEQ27301.1 - 6.7e-19 67.0 0.2 3.5e-09 35.9 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EEQ27301.1 - 5.1e-15 54.9 5.2 8.1e-15 54.2 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.18 EEQ27301.1 - 1.4e-10 41.2 0.0 1.4e-10 41.2 0.0 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 EEQ27301.1 - 5.2e-07 29.0 0.1 0.00029 20.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 EEQ27301.1 - 1.5e-05 25.0 1.6 0.00013 22.1 0.2 2.8 2 0 0 2 2 2 1 Bacterial SH3 domain DUF342 PF03961.8 EEQ27301.1 - 1.1 7.6 8.9 0.12 10.7 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Glyco_hydro_72 PF03198.9 EEQ27302.1 - 8e-127 422.5 3.2 9.6e-127 422.2 2.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EEQ27302.1 - 1.9e-06 27.3 0.6 1.7e-05 24.1 0.4 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 EEQ27303.1 - 2.2e-20 72.9 0.0 2.8e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27303.1 - 4.8e-09 35.6 0.0 7.1e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Arf PF00025.16 EEQ27304.1 - 8.5e-74 246.5 0.1 1e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ27304.1 - 1.1e-11 44.2 0.0 1.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEQ27304.1 - 1.2e-10 40.9 0.0 1.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEQ27304.1 - 2.5e-10 39.6 0.7 1.3e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEQ27304.1 - 9.9e-09 34.6 0.0 1.2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEQ27304.1 - 2.8e-08 34.2 0.0 3.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ27304.1 - 3.7e-06 26.8 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ27304.1 - 1.3e-05 24.6 0.0 0.0019 17.6 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEQ27304.1 - 0.007 15.6 0.5 0.034 13.4 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 EEQ27304.1 - 0.11 12.9 0.2 0.26 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Actin PF00022.14 EEQ27305.1 - 4.5e-26 91.1 0.0 8.5e-16 57.3 0.0 2.7 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EEQ27305.1 - 1.7e-05 23.6 0.0 0.009 14.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Paf1 PF03985.8 EEQ27306.1 - 2.7e-40 138.4 3.9 1.1e-25 90.3 0.0 3.0 2 1 0 2 2 2 2 Paf1 LON PF02190.11 EEQ27307.1 - 1.2e-20 74.1 0.0 2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EEQ27307.1 - 5.2e-09 35.9 9.6 1.3e-08 34.7 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ27307.1 - 4.1e-08 32.7 8.2 1.1e-07 31.4 5.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ27307.1 - 1.1e-07 31.5 9.5 2.3e-07 30.4 6.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ27307.1 - 3.5e-07 29.8 7.2 8.3e-07 28.6 5.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ27307.1 - 3.8e-07 29.6 7.3 7.3e-07 28.7 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEQ27307.1 - 7.5e-05 22.5 10.2 0.00016 21.4 7.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ27307.1 - 8e-05 22.2 1.0 8e-05 22.2 0.7 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EEQ27307.1 - 0.00071 19.1 3.9 0.0024 17.4 2.7 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EEQ27307.1 - 0.0013 18.1 7.5 0.0033 16.8 5.2 1.7 1 0 0 1 1 1 1 P-11 zinc finger U-box PF04564.10 EEQ27307.1 - 0.004 17.0 0.1 0.009 15.9 0.1 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 EEQ27307.1 - 0.0078 15.7 4.3 0.017 14.6 2.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EEQ27307.1 - 0.0099 15.9 4.7 0.029 14.4 3.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger DUF1272 PF06906.6 EEQ27307.1 - 0.15 11.9 4.4 0.35 10.7 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) RICTOR_N PF14664.1 EEQ27308.1 - 9.5e-134 445.6 0.7 2e-133 444.5 0.5 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EEQ27308.1 - 3.2e-91 304.3 0.8 4.5e-88 294.0 0.2 4.2 5 0 0 5 5 5 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EEQ27308.1 - 2.1e-43 146.9 0.0 7.8e-43 145.0 0.0 2.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EEQ27308.1 - 2.4e-25 88.2 1.8 1e-23 83.0 0.1 4.0 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EEQ27308.1 - 1.2e-09 37.7 11.2 1.2e-09 37.7 7.7 2.3 2 0 0 2 2 2 1 Hr1 repeat Uricase PF01014.13 EEQ27309.1 - 3.4e-77 257.1 1.2 4.6e-44 149.8 1.2 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 EEQ27309.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.13 EEQ27310.1 - 3.5e-40 137.0 0.0 4.4e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.14 EEQ27311.1 - 4.6e-38 130.1 0.3 5.2e-38 130.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EEQ27311.1 - 0.055 10.9 0.0 0.061 10.8 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein AAR2 PF05282.6 EEQ27312.1 - 5e-85 285.5 0.0 6.3e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.14 EEQ27313.1 - 1e-40 138.2 0.4 1.3e-40 138.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.12 EEQ27314.1 - 3.8e-13 48.9 0.0 6e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EEQ27314.1 - 5.8e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EEQ27314.1 - 7e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EEQ27314.1 - 0.0009 18.4 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EEQ27314.1 - 0.0073 15.7 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EEQ27314.1 - 0.017 14.7 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EEQ27314.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.4 EEQ27314.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Cytochrom_B561 PF03188.11 EEQ27315.1 - 3e-11 43.3 10.6 6.7e-11 42.1 7.4 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EEQ27315.1 - 0.029 14.2 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 DOMON domain zf-CW PF07496.10 EEQ27315.1 - 0.072 12.8 1.1 0.13 12.0 0.8 1.3 1 0 0 1 1 1 0 CW-type Zinc Finger RRM_6 PF14259.1 EEQ27316.1 - 0.00064 19.6 0.1 0.064 13.2 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Paf67 PF10255.4 EEQ27317.1 - 1.1e-155 518.5 0.0 1.2e-155 518.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EEQ27317.1 - 0.019 14.8 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fe-S_biosyn PF01521.15 EEQ27318.1 - 1.2e-09 38.1 0.0 4e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hemerythrin PF01814.18 EEQ27319.1 - 2.1e-13 50.5 0.8 3.3e-13 49.9 0.5 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MurB_C PF02873.11 EEQ27319.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Lactamase_B PF00753.22 EEQ27320.1 - 3.3e-10 39.9 0.9 6.5e-09 35.7 0.7 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEQ27320.1 - 6.3e-05 22.5 0.0 0.00016 21.2 0.0 1.7 1 1 0 2 2 2 1 Beta-lactamase superfamily domain MR_MLE PF01188.16 EEQ27320.1 - 0.055 14.0 0.1 14 6.3 0.0 3.3 3 0 0 3 3 3 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Aminotran_5 PF00266.14 EEQ27321.1 - 2.2e-09 36.5 0.0 3.6e-09 35.8 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ27321.1 - 0.0002 20.5 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EEQ27321.1 - 0.072 11.3 0.0 0.13 10.5 0.0 1.3 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF1077 PF06417.7 EEQ27322.1 - 2.6e-53 178.6 1.4 3.1e-53 178.4 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TMEM171 PF15471.1 EEQ27322.1 - 0.81 8.4 8.8 1.5 7.5 6.1 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 Adaptin_N PF01602.15 EEQ27324.1 - 5.4e-125 417.6 9.1 6.9e-125 417.3 6.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EEQ27324.1 - 9.1e-17 61.4 4.3 4.6e-16 59.1 0.4 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEQ27324.1 - 8.2e-16 58.0 4.2 8.2e-10 38.8 0.4 4.4 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EEQ27324.1 - 1.8e-10 39.9 4.5 0.034 14.2 0.0 5.4 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.4 EEQ27324.1 - 2.3e-05 24.0 0.1 0.7 9.6 0.0 4.2 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EEQ27324.1 - 8.7e-05 22.2 2.6 2.7 7.9 0.0 5.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EEQ27324.1 - 0.0017 17.7 2.1 2.1 7.6 0.0 3.2 2 1 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 EEQ27324.1 - 0.0019 18.6 8.6 6.5 7.3 0.1 6.1 6 1 1 7 7 7 1 HEAT-like repeat T_hemolysin PF12261.3 EEQ27324.1 - 0.12 11.9 0.1 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Thermostable hemolysin SH3_1 PF00018.23 EEQ27325.1 - 2.6e-10 39.4 0.2 5.3e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEQ27325.1 - 3.5e-10 39.2 0.0 7.4e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EEQ27325.1 - 5.5e-09 35.4 0.1 1.6e-08 33.9 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 EEQ27326.1 - 1.2e-18 67.0 0.1 2.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.13 EEQ27327.1 - 8.1e-58 193.4 0.6 9.6e-58 193.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EEQ27327.1 - 0.038 14.6 0.0 0.051 14.2 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 EEQ27328.1 - 6.5e-89 298.2 0.0 7.5e-89 298.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit FAT PF02259.18 EEQ27329.1 - 2.2e-126 421.5 0.5 2.2e-126 421.5 0.3 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 EEQ27329.1 - 4.2e-60 202.2 4.3 1.8e-57 193.7 0.6 3.7 3 1 0 3 3 3 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EEQ27329.1 - 2.5e-55 187.5 0.6 4.4e-55 186.7 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EEQ27329.1 - 6e-40 135.3 1.7 4.7e-39 132.5 0.1 3.5 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EEQ27329.1 - 9.7e-21 73.8 6.5 0.00014 22.1 0.0 8.2 8 2 1 9 9 9 6 HEAT repeats FATC PF02260.15 EEQ27329.1 - 6.8e-15 54.2 0.2 1.6e-14 53.0 0.2 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 EEQ27329.1 - 1.6e-14 53.8 7.9 0.0015 18.9 0.0 11.8 10 1 3 13 13 13 3 HEAT-like repeat HEAT PF02985.17 EEQ27329.1 - 5.6e-13 47.7 22.9 0.16 12.1 0.0 12.2 13 0 0 13 13 13 4 HEAT repeat UME PF08064.8 EEQ27329.1 - 3e-05 23.9 2.7 7.8 6.5 0.0 6.7 5 2 1 6 6 6 2 UME (NUC010) domain Methyltransf_18 PF12847.2 EEQ27332.1 - 6.6e-09 36.3 0.0 1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ27332.1 - 6e-08 32.5 0.0 9.8e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ27332.1 - 1.7e-06 27.6 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ27332.1 - 2.3e-06 27.9 0.0 5.1e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27332.1 - 1.7e-05 25.2 0.0 3.4e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ27332.1 - 0.0081 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EEQ27332.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EEQ27332.1 - 0.016 15.2 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EEQ27332.1 - 0.033 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase DUF706 PF05153.10 EEQ27333.1 - 6.4e-127 422.0 2.5 8e-127 421.7 1.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) Exonuc_X-T_C PF08411.5 EEQ27333.1 - 0.004 16.2 2.9 0.024 13.6 0.7 2.1 2 0 0 2 2 2 2 Exonuclease C-terminal Pam16 PF03656.8 EEQ27334.1 - 1.6e-36 124.8 0.2 2e-36 124.6 0.1 1.0 1 0 0 1 1 1 1 Pam16 AflR PF08493.5 EEQ27334.1 - 0.14 11.1 0.1 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Pex24p PF06398.6 EEQ27335.1 - 1.3e-95 320.2 0.2 1.8e-95 319.8 0.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DAHP_synth_1 PF00793.15 EEQ27339.1 - 4.5e-96 320.6 0.0 5.6e-96 320.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2458 PF10454.4 EEQ27340.1 - 2.5e-44 150.7 1.3 4.8e-44 149.8 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Ribosomal_L50 PF10501.4 EEQ27342.1 - 7.3e-19 67.7 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S SAP PF02037.22 EEQ27342.1 - 0.085 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 SAP domain Rtf2 PF04641.7 EEQ27343.1 - 4.8e-70 235.7 1.5 6e-70 235.4 1.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EEQ27343.1 - 4.6e-08 32.4 0.1 0.0083 15.6 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EEQ27343.1 - 3e-06 26.8 2.5 3.4e-06 26.6 0.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EEQ27343.1 - 0.0028 17.3 0.2 0.0052 16.4 0.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEQ27343.1 - 0.0057 16.4 0.3 0.035 13.9 0.0 2.2 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ27343.1 - 0.012 15.2 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Plasmodium_Vir PF05795.6 EEQ27343.1 - 0.1 11.7 3.6 0.14 11.3 2.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PRKCSH-like PF12999.2 EEQ27344.1 - 2.2e-45 154.3 6.3 9.4e-27 93.7 1.2 2.7 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EEQ27344.1 - 1e-33 116.0 0.4 2.8e-33 114.5 0.3 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EEQ27344.1 - 1.8e-09 38.2 1.2 6.5e-09 36.4 0.8 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein eIF3_N PF09440.5 EEQ27344.1 - 0.95 9.6 7.1 4.9 7.3 0.0 3.5 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain PAP_assoc PF03828.14 EEQ27345.1 - 7.2e-11 41.8 0.0 1.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEQ27345.1 - 1.9e-08 34.5 0.0 4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Aldo_ket_red PF00248.16 EEQ27346.1 - 1.5e-67 227.3 0.0 1.9e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.8 EEQ27347.1 - 5.6e-16 58.9 26.3 6.5e-16 58.7 16.1 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 EEQ27348.1 - 5.9e-18 64.2 0.0 5.9e-18 64.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PVL_ORF50 PF07768.6 EEQ27348.1 - 0.022 14.7 0.3 0.043 13.8 0.2 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family CENP-Q PF13094.1 EEQ27348.1 - 2.2 8.3 6.9 0.68 9.9 2.5 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Methyltransf_23 PF13489.1 EEQ27349.1 - 2.4e-17 63.1 0.1 3.9e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ27349.1 - 1.1e-05 25.9 0.0 0.025 15.1 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27349.1 - 0.00024 21.5 0.0 0.0023 18.4 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ27349.1 - 0.00098 18.7 0.0 0.52 9.8 0.0 2.7 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ27349.1 - 0.011 16.1 0.0 0.047 14.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ27349.1 - 0.015 15.7 0.0 0.11 12.9 0.0 2.3 2 1 1 3 3 3 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ27349.1 - 0.026 13.6 0.0 0.68 9.0 0.0 2.5 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EEQ27349.1 - 0.095 12.2 0.0 0.46 9.9 0.0 1.9 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EEQ27349.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HAD_2 PF13419.1 EEQ27350.1 - 2e-22 80.2 0.0 2.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ27350.1 - 2e-14 54.5 0.1 6.1e-09 36.5 0.1 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ27350.1 - 7.8e-12 45.7 0.0 1e-11 45.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ27350.1 - 6.3e-09 35.4 0.4 1.6e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EEQ27350.1 - 9.8e-07 28.6 0.0 0.00052 19.8 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EEQ27350.1 - 0.007 16.0 0.1 0.68 9.5 0.0 2.2 2 0 0 2 2 2 1 Acid Phosphatase Hydrolase_3 PF08282.7 EEQ27350.1 - 0.039 13.5 0.7 0.58 9.6 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase MTD PF01993.13 EEQ27350.1 - 0.049 12.6 0.0 0.09 11.7 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Peptidase_M35 PF02102.10 EEQ27351.1 - 8.1e-99 330.6 3.8 9.9e-99 330.3 2.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.1 EEQ27351.1 - 2e-05 24.1 1.9 4.5e-05 23.0 1.3 1.6 1 1 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 EEQ27351.1 - 0.0001 22.8 0.4 0.00021 21.8 0.2 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HC2 PF07382.6 EEQ27352.1 - 0.0053 16.6 14.8 0.0098 15.7 10.2 1.4 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF3906 PF13046.1 EEQ27352.1 - 0.063 12.8 0.1 0.24 11.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) HTH_22 PF13309.1 EEQ27352.1 - 0.091 12.5 3.7 1.7 8.4 0.1 3.1 2 0 0 2 2 2 0 HTH domain Actin PF00022.14 EEQ27353.1 - 2.9e-139 463.8 0.0 3.3e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Actin ATG22 PF11700.3 EEQ27354.1 - 1.5e-202 673.2 18.0 1.7e-202 673.1 12.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EEQ27354.1 - 2.7e-05 23.0 50.7 0.037 12.7 18.8 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Mpp10 PF04006.7 EEQ27355.1 - 9.4e-93 311.5 56.9 2.8e-92 310.0 39.4 2.0 1 1 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.4 EEQ27356.1 - 1.2e-47 161.5 0.0 1.6e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EEQ27356.1 - 0.0036 16.6 0.0 0.0073 15.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EEQ27356.1 - 0.022 13.8 0.1 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EEQ27356.1 - 0.034 14.7 0.0 0.054 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AhpC-TSA PF00578.16 EEQ27358.1 - 1.9e-22 79.2 0.0 2.7e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEQ27358.1 - 3.7e-12 46.0 0.0 5.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EEQ27358.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme NARP1 PF12569.3 EEQ27358.1 - 1.6 7.3 6.2 2.1 6.9 4.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAP PF07174.6 EEQ27358.1 - 3.6 6.8 10.1 5 6.3 7.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CH PF00307.26 EEQ27359.1 - 3.2e-64 213.7 0.0 2.5e-19 69.3 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EEQ27359.1 - 2.4e-07 30.7 0.9 1.9e-05 24.6 0.2 3.0 3 0 0 3 3 3 1 EF-hand domain pair CAMSAP_CH PF11971.3 EEQ27359.1 - 3.4e-05 23.4 0.0 2.6 7.7 0.0 4.2 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.27 EEQ27359.1 - 0.00049 19.1 1.1 0.32 10.4 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EEQ27359.1 - 0.001 18.7 0.8 0.046 13.6 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain Hydantoinase_B PF02538.9 EEQ27360.1 - 2.6e-203 676.0 0.0 3.5e-203 675.6 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EEQ27360.1 - 2.2e-94 315.8 0.5 4.5e-94 314.7 0.4 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEQ27360.1 - 9.1e-57 191.3 0.7 2.9e-55 186.4 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF3237 PF11578.3 EEQ27360.1 - 0.028 13.7 0.2 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) HSBP1 PF06825.7 EEQ27360.1 - 0.19 11.3 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 PC4 PF02229.11 EEQ27361.1 - 7.2e-22 76.3 0.1 1.2e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF4638 PF15472.1 EEQ27361.1 - 0.21 11.1 1.6 0.22 11.0 0.7 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4638) MIT PF04212.13 EEQ27362.1 - 1.8e-10 40.5 0.4 3.7e-10 39.5 0.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PAT1 PF09770.4 EEQ27362.1 - 0.92 7.6 5.9 1.2 7.2 4.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ubiq_cyt_C_chap PF03981.7 EEQ27363.1 - 1.2e-33 115.9 0.8 1.8e-33 115.3 0.1 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone BTB PF00651.26 EEQ27364.1 - 0.0061 16.5 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Fungal_trans_2 PF11951.3 EEQ27365.1 - 1e-33 116.5 1.7 1.4e-33 116.0 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EEQ27366.1 - 2.7e-30 105.2 48.2 1e-29 103.3 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.19 EEQ27367.1 - 1.9e-56 190.9 0.0 2.4e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EEQ27367.1 - 1.5e-22 79.4 0.0 2.9e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TIP41 PF04176.8 EEQ27369.1 - 4.5e-78 260.6 0.0 5.4e-78 260.4 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 EEQ27370.1 - 3.2e-69 232.9 0.0 4.1e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27370.1 - 8.9e-43 146.2 0.0 1.2e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ27370.1 - 1.9e-07 30.3 0.0 1.1e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEQ27370.1 - 9.1e-05 21.6 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEQ27370.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EEQ27370.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 EEQ27371.1 - 1.9e-67 226.0 3.4 2.7e-67 225.5 2.4 1.2 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EEQ27371.1 - 0.0012 18.5 2.1 0.0013 18.3 0.8 1.8 1 1 1 2 2 2 1 SprT-like family Tox-MPTase2 PF15638.1 EEQ27371.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 PALP PF00291.20 EEQ27372.1 - 5.5e-57 193.3 0.1 6.7e-57 193.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EEQ27372.1 - 7e-07 28.9 0.0 6.1e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 CBS domain SRPRB PF09439.5 EEQ27373.1 - 1.2e-28 99.6 0.1 4.7e-27 94.3 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EEQ27373.1 - 2.7e-06 26.7 0.0 0.00029 20.1 0.0 2.8 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEQ27373.1 - 5.2e-05 23.1 0.0 7.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EEQ27373.1 - 0.00042 20.3 0.5 0.0011 18.9 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EEQ27373.1 - 0.00046 19.3 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EEQ27373.1 - 0.0031 17.6 0.0 0.0069 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EEQ27373.1 - 0.0096 16.4 0.2 0.4 11.2 0.1 2.5 1 1 0 1 1 1 1 Miro-like protein Zeta_toxin PF06414.7 EEQ27373.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 EEQ27373.1 - 0.045 13.4 0.0 0.091 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EEQ27373.1 - 0.053 13.7 0.6 0.38 10.9 0.4 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EEQ27373.1 - 0.065 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EEQ27373.1 - 0.066 12.6 0.0 6.5 6.1 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EEQ27373.1 - 0.08 12.4 0.1 8.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EEQ27373.1 - 0.1 12.9 0.1 0.32 11.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 EEQ27373.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EEQ27373.1 - 0.12 11.7 0.2 1.2 8.5 0.2 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 EEQ27373.1 - 0.15 11.5 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation KRE9 PF05390.6 EEQ27374.1 - 5.2e-10 39.6 1.3 5.2e-10 39.6 0.9 1.9 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 EEQ27374.1 - 1.6e-09 38.1 0.0 3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AA_kinase PF00696.23 EEQ27375.1 - 9.3e-35 120.3 1.4 1.5e-34 119.6 1.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EEQ27375.1 - 9.4e-10 38.0 0.1 9.3e-09 34.8 0.0 2.4 2 0 0 2 2 2 1 PUA domain Pkinase PF00069.20 EEQ27376.1 - 5.4e-42 143.7 0.0 3.1e-41 141.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27376.1 - 9.3e-24 83.8 0.0 1.5e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ27376.1 - 0.0092 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ27376.1 - 0.099 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EEQ27376.1 - 0.58 8.8 0.1 0.84 8.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AMP-binding PF00501.23 EEQ27377.1 - 1.4e-243 807.6 0.0 1.4e-88 297.1 0.0 4.2 3 1 1 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EEQ27377.1 - 6.7e-177 586.6 0.0 4.7e-37 127.4 0.0 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EEQ27377.1 - 2.9e-51 171.6 17.5 1.1e-09 38.3 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ27377.1 - 6.7e-23 81.4 0.0 1.4e-07 32.3 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EEQ27377.1 - 5.2e-07 29.8 3.0 0.029 14.6 0.0 4.3 4 0 0 4 4 4 2 HxxPF-repeated domain WES_acyltransf PF03007.11 EEQ27377.1 - 0.013 15.1 0.5 71 2.8 0.0 4.4 4 0 0 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1524 PF07510.6 EEQ27377.1 - 0.068 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) RPM2 PF08579.6 EEQ27377.1 - 0.083 13.0 0.0 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) AATase PF07247.7 EEQ27377.1 - 0.45 8.9 0.0 6 5.2 0.0 2.6 3 0 0 3 3 3 0 Alcohol acetyltransferase K_oxygenase PF13434.1 EEQ27378.1 - 8.4e-109 363.5 0.0 1e-108 363.3 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EEQ27378.1 - 1.6e-10 41.4 0.0 3.7e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ27378.1 - 1.3e-07 31.5 0.0 1.4e-05 24.8 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEQ27378.1 - 1.6e-06 28.1 0.0 0.005 16.7 0.0 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 EEQ27380.1 - 2.5e-42 143.0 0.0 1.4e-18 67.0 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ27380.1 - 2.9e-34 115.1 0.2 3.6e-10 39.1 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EEQ27380.1 - 2.3e-26 91.1 4.2 4.2e-08 33.1 0.0 4.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ27380.1 - 6.1e-25 87.1 3.9 3.5e-08 33.7 0.0 5.2 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ27380.1 - 2.9e-22 76.5 0.5 1.4e-08 34.1 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat zf-DHHC PF01529.15 EEQ27380.1 - 5.6e-07 29.1 5.6 5.6e-07 29.1 3.9 3.1 2 1 1 3 3 3 2 DHHC palmitoyltransferase YfhO PF09586.5 EEQ27380.1 - 0.011 13.7 5.1 0.02 12.9 3.5 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO OB_NTP_bind PF07717.11 EEQ27381.1 - 7.1e-29 99.9 0.0 2.1e-28 98.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEQ27381.1 - 1.1e-24 86.3 0.0 1.1e-24 86.3 0.0 2.9 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ27381.1 - 1.4e-12 47.2 0.0 3.6e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ27381.1 - 2.7e-05 23.7 0.0 6.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEQ27381.1 - 7.8e-05 22.8 0.0 0.00034 20.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain PWI PF01480.12 EEQ27381.1 - 0.00036 20.5 0.0 0.00084 19.3 0.0 1.6 1 0 0 1 1 1 1 PWI domain T2SE PF00437.15 EEQ27381.1 - 0.00041 19.3 0.0 0.00083 18.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EEQ27381.1 - 0.0076 16.3 0.0 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 EEQ27381.1 - 0.038 13.7 0.4 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain SRP54 PF00448.17 EEQ27381.1 - 0.044 13.2 0.0 0.098 12.0 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 EEQ27381.1 - 0.087 12.3 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EEQ27381.1 - 0.19 12.0 0.0 0.19 12.0 0.0 3.5 1 1 1 2 2 1 0 AAA domain ABC_tran PF00005.22 EEQ27381.1 - 1.4 9.2 5.4 0.45 10.8 0.1 2.8 2 1 1 3 3 3 0 ABC transporter Lipase_2 PF01674.13 EEQ27383.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) APH PF01636.18 EEQ27383.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family CTK3_C PF12350.3 EEQ27383.1 - 0.15 12.1 0.6 0.31 11.0 0.4 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus Cyt-b5 PF00173.23 EEQ27385.1 - 6.9e-17 61.0 0.1 7.7e-17 60.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4291 PF14124.1 EEQ27386.1 - 2e-75 252.4 0.2 2.3e-75 252.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Mcp5_PH PF12814.2 EEQ27387.1 - 4.7e-31 107.2 0.2 2e-20 72.9 0.0 2.4 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology DUF3584 PF12128.3 EEQ27387.1 - 0.11 9.8 11.1 0.16 9.2 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EEQ27387.1 - 3.1 7.5 18.4 80 2.9 12.3 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EEQ27387.1 - 6.6 5.5 14.1 2.2 7.1 7.8 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fez1 PF06818.10 EEQ27387.1 - 6.8 6.6 20.6 0.66 9.9 10.8 1.8 2 0 0 2 2 2 0 Fez1 GHMP_kinases_N PF00288.21 EEQ27389.1 - 1.1e-17 63.8 0.1 5.7e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEQ27389.1 - 2.9e-10 40.1 0.2 6.9e-10 38.9 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EEQ27389.1 - 0.017 14.4 0.1 0.04 13.1 0.0 1.6 1 0 0 1 1 1 0 Galactokinase galactose-binding signature LigT_PEase PF02834.11 EEQ27389.1 - 0.019 14.9 0.0 0.075 13.0 0.0 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase AMP-binding PF00501.23 EEQ27390.1 - 8.6e-78 261.5 0.0 1e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ27390.1 - 9.6e-14 52.0 0.0 2.9e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ras PF00071.17 EEQ27391.1 - 4.2e-50 169.2 0.5 8.4e-49 165.0 0.3 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEQ27391.1 - 1.3e-16 61.2 0.1 8.3e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEQ27391.1 - 0.00018 20.7 0.0 0.0014 17.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEQ27391.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEQ27391.1 - 0.048 12.7 0.1 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EEQ27391.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EEQ27391.1 - 0.15 11.3 0.2 2 7.6 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B Septin PF00735.13 EEQ27391.1 - 0.16 10.9 0.7 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 Septin MFS_1 PF07690.11 EEQ27392.1 - 5.4e-31 107.5 34.9 8.1e-31 106.9 24.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SHMT PF00464.14 EEQ27394.1 - 2.8e-196 651.6 0.0 3.3e-196 651.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Mor PF08765.6 EEQ27394.1 - 0.1 12.4 0.1 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Mor transcription activator family MOSC PF03473.12 EEQ27395.1 - 8.5e-15 54.4 0.0 1.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EEQ27395.1 - 5.5e-12 45.4 0.0 2.7e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain AF1Q PF15017.1 EEQ27395.1 - 0.059 13.2 1.0 0.15 11.9 0.4 1.8 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Ribosomal_60s PF00428.14 EEQ27395.1 - 8.1 6.9 7.6 16 6.0 5.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2235 PF09994.4 EEQ27396.1 - 3e-90 302.3 0.0 3.8e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Patatin PF01734.17 EEQ27397.1 - 8.5e-28 97.6 0.0 1.9e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Mg_trans_NIPA PF05653.9 EEQ27398.1 - 1.8e-86 289.8 25.5 2.5e-86 289.3 17.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EEQ27398.1 - 4.5e-07 30.0 2.8 4.5e-07 30.0 2.0 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EEQ27398.1 - 9.3e-06 25.7 5.5 9.3e-06 25.7 3.8 3.1 2 1 1 3 3 3 1 EamA-like transporter family PTCB-BRCT PF12738.2 EEQ27399.1 - 0.00051 19.8 0.5 0.001 18.9 0.0 1.7 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EEQ27399.1 - 0.0079 16.3 0.0 0.04 14.0 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HA2 PF04408.18 EEQ27401.1 - 7.8e-21 74.0 0.1 2.2e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ27401.1 - 1.3e-11 44.1 0.2 3.6e-11 42.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ27401.1 - 5e-09 35.8 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEQ27401.1 - 1.4e-08 34.9 0.2 2.3e-07 31.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ27401.1 - 0.0031 16.9 0.0 0.0089 15.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EEQ27401.1 - 0.0076 15.1 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.1 EEQ27401.1 - 0.0097 16.2 1.1 4.6 7.5 0.0 4.0 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ27401.1 - 0.018 14.4 0.0 0.051 13.0 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EEQ27401.1 - 0.03 13.1 0.3 0.16 10.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EEQ27401.1 - 0.039 13.6 0.0 0.89 9.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 EEQ27401.1 - 0.049 13.9 0.0 0.049 13.9 0.0 3.0 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.22 EEQ27401.1 - 0.049 13.9 0.3 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter DUF3554 PF12074.3 EEQ27402.1 - 5.9e-73 246.2 1.5 1.1e-71 242.0 0.4 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3554) HEAT PF02985.17 EEQ27402.1 - 1.2e-33 112.0 31.4 0.051 13.6 0.0 21.7 25 0 0 25 25 25 9 HEAT repeat HEAT_2 PF13646.1 EEQ27402.1 - 2.3e-31 107.9 39.8 9e-11 41.9 0.0 15.3 9 4 6 15 15 15 6 HEAT repeats HEAT_EZ PF13513.1 EEQ27402.1 - 1.7e-25 88.7 41.0 6.6e-06 26.4 0.0 21.1 15 6 8 23 23 23 7 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ27402.1 - 1.1e-12 48.1 0.0 0.34 11.3 0.0 8.3 7 1 2 9 9 9 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EEQ27402.1 - 6.4e-07 29.3 0.8 0.54 10.0 0.0 6.9 8 1 2 10 10 10 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EEQ27402.1 - 2.4e-06 27.5 5.9 0.22 11.3 0.0 6.5 6 1 1 7 7 7 2 Parkin co-regulated protein Cohesin_HEAT PF12765.2 EEQ27402.1 - 0.0037 17.1 7.3 3.4 7.7 0.1 6.3 7 0 0 7 7 7 2 HEAT repeat associated with sister chromatid cohesion FANCI_S2 PF14676.1 EEQ27402.1 - 0.013 15.3 2.4 5.4 6.9 0.0 4.2 5 0 0 5 5 5 0 FANCI solenoid 2 TIP120 PF08623.5 EEQ27402.1 - 0.047 13.2 0.6 5.3 6.5 0.0 4.2 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Ribosomal_L19e PF01280.15 EEQ27403.1 - 4.5e-61 204.9 7.7 4.5e-61 204.9 5.3 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EEQ27403.1 - 0.025 13.7 1.3 0.029 13.5 0.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4239 PF14023.1 EEQ27403.1 - 0.03 13.6 1.5 0.043 13.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF349 PF03993.7 EEQ27403.1 - 4.7 7.4 13.3 17 5.6 0.0 3.2 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) Zn_clus PF00172.13 EEQ27409.1 - 1.3e-09 37.8 11.0 2.1e-09 37.1 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 EEQ27409.1 - 0.91 9.0 4.5 1.7 8.2 3.2 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 adh_short PF00106.20 EEQ27411.1 - 6.6e-22 78.1 7.4 2.5e-21 76.3 5.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ27411.1 - 1.3e-09 38.1 0.0 1.9e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ27411.1 - 2.5e-09 37.0 5.7 1.2e-06 28.3 5.1 2.9 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EEQ27411.1 - 0.00015 21.8 0.1 0.00047 20.2 0.0 1.7 1 1 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EEQ27411.1 - 0.0034 16.3 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EEQ27411.1 - 0.0088 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fib_alpha PF08702.5 EEQ27412.1 - 0.078 13.0 15.7 0.049 13.7 2.7 3.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 EEQ27412.1 - 0.92 8.6 5.8 0.61 9.2 1.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Trp_oprn_chp PF09534.5 EEQ27412.1 - 1.4 8.4 0.3 30 4.1 0.2 2.9 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Herpes_U30 PF04523.8 EEQ27412.1 - 5.2 4.3 0.3 9.5 3.5 0.2 1.3 1 0 0 1 1 1 0 Herpes virus tegument protein U30 CorA PF01544.13 EEQ27413.1 - 8.3e-41 139.9 0.8 2e-40 138.6 0.5 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.2 EEQ27414.1 - 2.5e-151 503.9 2.1 2.5e-151 503.9 1.5 2.0 3 0 0 3 3 3 1 Vacuolar segregation subunit 7 RNA_pol_Rpc4 PF05132.9 EEQ27414.1 - 0.1 12.5 6.9 0.3 11.0 4.8 1.8 1 0 0 1 1 1 0 RNA polymerase III RPC4 EIIBC-GUT_N PF03612.9 EEQ27414.1 - 0.11 12.1 1.1 0.2 11.2 0.8 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Beta-lactamase PF00144.19 EEQ27415.1 - 5.3e-31 107.8 0.0 9.2e-31 107.0 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase DUF2613 PF11021.3 EEQ27417.1 - 0.044 13.4 0.2 0.2 11.3 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Amidohydro_1 PF01979.15 EEQ27418.1 - 6.1e-10 39.2 3.1 1.2e-09 38.2 2.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EEQ27418.1 - 5.4e-08 32.5 0.3 2.9e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EEQ27418.1 - 1.8e-05 24.1 2.3 9.1e-05 21.8 0.2 2.3 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EEQ27418.1 - 0.00032 20.8 3.4 0.0061 16.6 2.4 2.8 1 1 0 1 1 1 1 Amidohydrolase Abhydrolase_6 PF12697.2 EEQ27420.1 - 2e-32 112.9 0.0 2.3e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ27420.1 - 1.1e-17 64.0 0.0 6e-17 61.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ27420.1 - 1.1e-14 54.5 0.0 3.1e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEQ27420.1 - 6.5e-08 32.3 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EEQ27420.1 - 0.00011 20.7 0.0 0.00013 20.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.15 EEQ27420.1 - 0.047 13.9 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EEQ27420.1 - 0.053 13.1 0.1 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.13 EEQ27421.1 - 1.2e-17 63.6 0.1 1.2e-17 63.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Spore_YpjB PF09577.5 EEQ27421.1 - 0.03 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Striatin PF08232.7 EEQ27421.1 - 0.13 12.6 1.1 0.25 11.6 0.7 1.4 1 0 0 1 1 1 0 Striatin family Ribosomal_L44 PF00935.14 EEQ27422.1 - 9.3e-35 118.4 11.5 1.4e-34 117.9 8.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 ubiquitin PF00240.18 EEQ27423.1 - 2.6e-23 81.1 0.0 2.9e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEQ27423.1 - 1.1e-14 53.8 0.0 1.2e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEQ27423.1 - 7e-05 22.9 0.0 0.00022 21.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Ferritin_2 PF13668.1 EEQ27424.1 - 9.9e-19 67.6 0.1 1.5e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain PilN PF05137.8 EEQ27424.1 - 0.0086 15.8 0.2 3.2 7.6 0.0 2.4 2 0 0 2 2 2 2 Fimbrial assembly protein (PilN) Rav1p_C PF12234.3 EEQ27425.1 - 8e-271 899.7 0.5 1e-270 899.3 0.4 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EEQ27425.1 - 7.2e-05 22.5 5.7 0.61 10.0 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat OPT PF03169.10 EEQ27426.1 - 9.2e-159 529.7 15.5 1.1e-158 529.5 10.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 EEQ27426.1 - 0.025 14.5 9.2 0.53 10.3 0.3 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) SH3_9 PF14604.1 EEQ27427.1 - 3.3e-09 36.1 0.0 5.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ27427.1 - 5.1e-07 28.9 0.0 7.9e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEQ27427.1 - 2e-06 27.1 0.0 3.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4366 PF14283.1 EEQ27427.1 - 0.28 10.5 8.3 0.066 12.6 0.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) IncA PF04156.9 EEQ27427.1 - 0.63 9.5 0.0 0.63 9.5 0.0 1.7 2 0 0 2 2 2 0 IncA protein ABC_tran PF00005.22 EEQ27428.1 - 2.1e-40 138.1 0.0 2.4e-19 70.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ27428.1 - 1.5e-31 109.8 34.3 6.6e-20 71.6 12.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EEQ27428.1 - 5.6e-11 42.1 0.0 0.00074 18.8 0.0 3.3 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ27428.1 - 2.7e-09 37.4 0.1 0.55 10.1 0.0 4.2 3 1 1 4 4 4 3 AAA domain AAA_16 PF13191.1 EEQ27428.1 - 3.8e-07 30.2 0.9 0.0021 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EEQ27428.1 - 0.00032 20.8 0.1 0.02 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEQ27428.1 - 0.00052 20.2 1.4 0.027 14.6 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EEQ27428.1 - 0.00085 19.0 0.0 0.045 13.4 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase SbcCD_C PF13558.1 EEQ27428.1 - 0.0034 17.2 0.8 3.7 7.5 0.0 3.9 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EEQ27428.1 - 0.0038 17.1 0.0 0.18 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EEQ27428.1 - 0.0096 14.8 0.0 0.04 12.8 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 EEQ27428.1 - 0.016 14.9 0.2 0.098 12.4 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 EEQ27428.1 - 0.018 14.5 0.1 1 8.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EEQ27428.1 - 0.025 13.6 0.0 0.79 8.7 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.14 EEQ27428.1 - 0.033 13.6 0.5 0.087 12.2 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 EEQ27428.1 - 0.056 12.9 0.1 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EEQ27428.1 - 0.061 12.8 0.3 5 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EEQ27428.1 - 0.081 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EEQ27428.1 - 0.084 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EEQ27428.1 - 0.12 12.3 0.2 12 5.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EEQ27428.1 - 0.16 11.8 0.0 0.96 9.3 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.1 EEQ27428.1 - 0.22 11.0 0.0 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EEQ27428.1 - 0.35 9.4 3.1 6.9 5.1 0.0 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Pkinase PF00069.20 EEQ27429.1 - 1.8e-41 141.9 0.0 2.5e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27429.1 - 2.9e-14 52.7 0.0 4.4e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ27429.1 - 0.0036 17.0 0.1 0.022 14.4 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family PA28_alpha PF02251.13 EEQ27429.1 - 0.039 14.1 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Kdo PF06293.9 EEQ27429.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ27429.1 - 0.073 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like muHD PF10291.4 EEQ27430.1 - 4.4e-69 232.5 0.0 7e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EEQ27430.1 - 1.1e-05 25.5 0.5 3.6e-05 23.8 0.0 2.1 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Ndc1_Nup PF09531.5 EEQ27430.1 - 0.028 12.8 0.2 0.061 11.7 0.1 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Laminin_II PF06009.7 EEQ27430.1 - 0.091 12.5 5.0 0.12 12.0 2.6 1.9 2 0 0 2 2 2 0 Laminin Domain II Spc7 PF08317.6 EEQ27430.1 - 0.4 9.2 5.5 0.64 8.6 3.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_M20 PF01546.23 EEQ27431.1 - 3.5e-29 101.6 0.0 5.3e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEQ27431.1 - 1.1e-15 57.2 0.0 3.1e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain MAD PF05557.8 EEQ27432.1 - 4.9e-51 173.7 75.8 3e-41 141.3 52.6 2.3 2 0 0 2 2 2 2 Mitotic checkpoint protein Bacillus_HBL PF05791.6 EEQ27432.1 - 0.00042 19.7 5.8 0.00042 19.7 4.0 6.4 5 2 2 7 7 7 1 Bacillus haemolytic enterotoxin (HBL) Mto2_bdg PF12808.2 EEQ27432.1 - 0.0062 16.6 4.2 0.0062 16.6 2.9 7.7 7 1 1 8 8 8 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Arginosuc_synth PF00764.14 EEQ27433.1 - 8e-127 423.4 0.0 1.6e-126 422.4 0.0 1.4 1 1 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EEQ27433.1 - 0.00047 19.7 0.0 0.00064 19.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EEQ27433.1 - 0.0021 17.3 0.0 0.0032 16.7 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EEQ27433.1 - 0.027 13.0 0.0 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase DNA_pol3_gamma3 PF12169.3 EEQ27433.1 - 0.12 12.1 0.1 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III RasGEF PF00617.14 EEQ27434.1 - 3.5e-44 150.7 0.1 5.5e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEQ27434.1 - 6.3e-14 51.9 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif Ank_2 PF12796.2 EEQ27435.1 - 3.2e-17 62.6 0.1 3.1e-16 59.4 0.0 2.7 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) DIL PF01843.14 EEQ27435.1 - 3.7e-16 58.9 9.6 3.9e-11 42.7 0.1 3.0 4 0 0 4 4 4 2 DIL domain Ank PF00023.25 EEQ27435.1 - 6.6e-15 54.0 0.1 1.1e-05 24.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEQ27435.1 - 3.8e-11 42.8 0.0 5.7e-06 26.4 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ27435.1 - 4.4e-09 36.6 0.3 0.0021 18.4 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ27435.1 - 2e-06 27.4 2.2 0.016 15.4 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat BTB PF00651.26 EEQ27437.1 - 6.4e-13 48.6 0.3 1.7e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Bacteriocin_IIi PF11758.3 EEQ27437.1 - 0.06 12.9 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin SKG6 PF08693.5 EEQ27438.1 - 0.00027 20.1 0.0 0.00059 19.1 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RabGAP-TBC PF00566.13 EEQ27439.1 - 2.1e-34 118.8 0.0 3.5e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TPP_enzyme_N PF02776.13 EEQ27440.1 - 4.9e-42 143.3 0.0 1.1e-41 142.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEQ27440.1 - 1.4e-19 70.2 0.1 2e-18 66.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEQ27440.1 - 1.7e-16 60.2 0.0 3.6e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain S-AdoMet_synt_C PF02773.11 EEQ27440.1 - 0.036 13.7 0.2 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, C-terminal domain Mo25 PF08569.6 EEQ27441.1 - 3.2e-119 397.9 0.0 9.8e-112 373.2 0.0 2.0 2 0 0 2 2 2 2 Mo25-like Methyltransf_31 PF13847.1 EEQ27442.1 - 9.8e-12 44.7 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEQ27442.1 - 6.8e-09 35.2 0.0 1.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EEQ27442.1 - 1.8e-08 34.7 0.0 3.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ27442.1 - 7.6e-08 32.9 0.1 3.1e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ27442.1 - 6.3e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ27442.1 - 4.4e-06 26.1 0.1 7.9e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EEQ27442.1 - 1.4e-05 24.8 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ27442.1 - 0.00028 21.1 0.1 0.00096 19.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EEQ27442.1 - 0.00044 19.0 0.0 0.00062 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 EEQ27442.1 - 0.0058 17.0 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EEQ27442.1 - 0.0064 15.4 0.0 0.0088 14.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TehB PF03848.9 EEQ27442.1 - 0.026 13.7 0.1 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 EEQ27442.1 - 0.03 14.3 0.1 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Met_10 PF02475.11 EEQ27442.1 - 0.043 13.4 0.1 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.14 EEQ27442.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EEQ27442.1 - 0.049 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EEQ27442.1 - 0.072 12.1 0.0 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EEQ27442.1 - 0.099 13.4 0.0 0.4 11.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain ADH_zinc_N PF00107.21 EEQ27442.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Cir_N PF10197.4 EEQ27443.1 - 0.0035 17.3 8.1 0.0035 17.3 5.6 3.7 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR SRP1_TIP1 PF00660.12 EEQ27443.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Seripauperin and TIP1 family PPV_E1_N PF00524.13 EEQ27443.1 - 2.8 8.1 13.5 0.065 13.4 2.7 2.4 2 0 0 2 2 2 0 E1 Protein, N terminal domain Rsc14 PF08586.5 EEQ27443.1 - 5.2 7.6 6.6 7 7.1 0.4 2.9 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit AAA PF00004.24 EEQ27444.1 - 9.6e-54 181.1 0.0 1.4e-38 132.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EEQ27444.1 - 5e-13 48.8 0.0 1.2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EEQ27444.1 - 1.6e-10 40.4 0.1 3.2e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EEQ27444.1 - 1.9e-09 37.7 0.2 0.00095 19.3 0.0 3.8 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 EEQ27444.1 - 5.3e-09 36.9 0.1 0.0041 17.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ27444.1 - 1.2e-08 35.1 0.1 0.0021 18.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EEQ27444.1 - 1.7e-08 34.4 0.0 0.0054 16.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EEQ27444.1 - 1.7e-08 34.0 1.9 0.0048 16.6 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA_5 PF07728.9 EEQ27444.1 - 2.5e-08 33.7 0.0 0.0013 18.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EEQ27444.1 - 9e-08 31.4 0.0 0.0062 15.6 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EEQ27444.1 - 9.2e-08 31.1 0.0 0.007 15.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 EEQ27444.1 - 1e-07 32.3 0.0 0.0059 16.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EEQ27444.1 - 2.5e-07 30.0 0.1 0.0046 16.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EEQ27444.1 - 2.8e-07 30.6 0.0 6.1e-05 22.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EEQ27444.1 - 4.8e-07 29.7 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EEQ27444.1 - 8.8e-07 29.0 0.0 0.059 13.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EEQ27444.1 - 3e-06 26.7 0.1 0.039 13.3 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_24 PF13479.1 EEQ27444.1 - 1.5e-05 24.6 0.4 0.12 11.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EEQ27444.1 - 1.6e-05 24.1 0.0 0.089 11.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 EEQ27444.1 - 2.1e-05 24.2 0.1 0.031 13.9 0.0 3.0 2 1 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 EEQ27444.1 - 4.5e-05 22.9 1.8 0.45 9.8 0.0 3.4 2 2 2 4 4 4 2 AAA domain KaiC PF06745.8 EEQ27444.1 - 6.2e-05 22.2 0.8 0.019 14.1 0.1 2.8 2 1 1 3 3 3 1 KaiC AAA_28 PF13521.1 EEQ27444.1 - 7.2e-05 22.8 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EEQ27444.1 - 0.00012 21.0 0.2 0.23 10.2 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.11 EEQ27444.1 - 0.00024 20.4 0.2 0.66 9.1 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein AAA_3 PF07726.6 EEQ27444.1 - 0.00032 20.3 0.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EEQ27444.1 - 0.00032 21.0 0.3 0.047 14.0 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 EEQ27444.1 - 0.00069 19.1 0.0 0.57 9.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.4 EEQ27444.1 - 0.0015 17.5 0.0 0.47 9.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EEQ27444.1 - 0.0016 18.0 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EEQ27444.1 - 0.0021 17.8 0.3 3.8 7.1 0.2 3.3 2 1 1 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 EEQ27444.1 - 0.0031 17.1 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EEQ27444.1 - 0.0031 16.7 0.1 0.59 9.2 0.0 2.6 3 0 0 3 3 2 1 Chromatin associated protein KTI12 Parvo_NS1 PF01057.12 EEQ27444.1 - 0.0039 16.0 0.0 0.4 9.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EEQ27444.1 - 0.01 15.3 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EEQ27444.1 - 0.014 15.4 0.1 9.1 6.3 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EEQ27444.1 - 0.017 14.8 0.1 13 5.4 0.0 3.3 3 0 0 3 3 3 0 NTPase DEAD PF00270.24 EEQ27444.1 - 0.019 14.4 0.3 20 4.6 0.0 4.0 2 2 0 4 4 4 0 DEAD/DEAH box helicase ResIII PF04851.10 EEQ27444.1 - 0.035 13.9 0.1 10 5.9 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 EEQ27444.1 - 0.052 12.9 0.2 4.7 6.5 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain KAP_NTPase PF07693.9 EEQ27444.1 - 0.072 12.0 0.0 4.8 6.0 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain T2SE PF00437.15 EEQ27444.1 - 0.074 11.9 0.0 6.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EEQ27444.1 - 0.085 12.3 0.2 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.11 EEQ27444.1 - 0.099 11.8 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KxDL PF10241.4 EEQ27446.1 - 0.024 14.5 0.3 0.26 11.2 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein HATPase_c PF02518.21 EEQ27447.1 - 7.8e-22 77.0 0.3 2.1e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEQ27447.1 - 3.8e-21 75.1 0.1 8e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EEQ27447.1 - 2e-16 59.7 0.0 5.7e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EEQ27447.1 - 2.5e-07 30.7 3.1 0.61 10.2 0.0 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 EEQ27447.1 - 5.8e-06 26.6 0.2 0.021 15.2 0.0 4.0 3 1 0 3 3 3 1 PAS domain PAS_4 PF08448.5 EEQ27447.1 - 0.0044 17.0 0.3 0.02 14.9 0.1 2.2 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.1 EEQ27447.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c PF02518.21 EEQ27448.1 - 3.9e-29 100.6 0.1 1.2e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EEQ27448.1 - 2e-20 72.5 0.0 8.5e-20 70.5 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EEQ27448.1 - 7e-20 71.1 0.1 1.8e-19 69.7 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain GAF_2 PF13185.1 EEQ27448.1 - 7e-11 42.8 0.0 1.7e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 EEQ27448.1 - 2.8e-10 40.4 0.1 2.5e-09 37.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain GAF PF01590.21 EEQ27448.1 - 6.2e-08 32.9 0.0 2.5e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.20 EEQ27448.1 - 2.7e-07 30.0 0.0 1.3e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 EEQ27448.1 - 1.3e-06 28.5 0.0 3.4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 EEQ27448.1 - 9.8e-05 22.0 0.0 0.00023 20.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 EEQ27448.1 - 0.00057 20.0 0.0 0.065 13.3 0.0 3.3 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.12 EEQ27448.1 - 0.001 18.7 2.6 0.81 9.7 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat ArgK PF03308.11 EEQ27448.1 - 0.0016 17.2 0.0 0.0038 16.0 0.0 1.5 1 0 0 1 1 1 1 ArgK protein TPR_11 PF13414.1 EEQ27448.1 - 0.0051 16.4 1.4 0.056 13.0 0.2 3.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EEQ27448.1 - 0.011 15.3 0.8 3.7 7.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Allantoicase PF03561.10 EEQ27449.1 - 7.5e-94 311.2 0.0 2.2e-49 166.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.11 EEQ27450.1 - 2.3e-16 59.8 2.0 2.3e-16 59.8 1.4 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 Cytochrom_B_N PF00033.14 EEQ27450.1 - 0.0024 17.2 9.9 0.0074 15.6 1.0 2.9 1 1 2 3 3 3 2 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 EEQ27450.1 - 0.02 14.2 10.2 2.8 7.2 7.1 2.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4271 PF14093.1 EEQ27450.1 - 0.025 14.2 4.9 0.037 13.7 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) PepSY_TM_1 PF13172.1 EEQ27450.1 - 0.078 12.7 1.1 0.5 10.1 0.0 2.7 2 0 0 2 2 2 0 PepSY-associated TM helix DUF2306 PF10067.4 EEQ27450.1 - 0.22 11.6 13.7 0.092 12.8 0.6 3.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Bax1-I PF01027.15 EEQ27450.1 - 1 8.8 14.5 2.6 7.5 10.0 1.7 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2427 PF10348.4 EEQ27450.1 - 1.4 8.5 7.4 0.16 11.5 0.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) PepSY_TM_2 PF13703.1 EEQ27450.1 - 2.4 8.4 12.6 5.3 7.2 0.3 3.9 2 1 2 4 4 4 0 PepSY-associated TM helix DUF1129 PF06570.6 EEQ27450.1 - 2.8 7.2 8.0 3.1 7.0 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) tRNA-synt_2b PF00587.20 EEQ27451.1 - 8.2e-22 77.6 0.0 1.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EEQ27451.1 - 1.5e-05 24.9 7.2 0.0064 16.4 0.3 2.2 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DUF2205 PF10224.4 EEQ27451.1 - 0.076 12.5 5.1 0.41 10.2 0.1 2.5 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF2656 PF10847.3 EEQ27451.1 - 0.09 12.7 0.3 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) tRNA-synt_2d PF01409.15 EEQ27451.1 - 0.1 11.7 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) V_ATPase_I PF01496.14 EEQ27451.1 - 0.3 8.8 0.6 0.41 8.4 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIF_alpha PF05793.7 EEQ27452.1 - 0.011 14.1 4.1 0.043 12.2 3.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SNARE PF05739.14 EEQ27452.1 - 0.061 13.0 0.6 3 7.6 0.1 2.3 2 0 0 2 2 2 0 SNARE domain DUF4360 PF14273.1 EEQ27453.1 - 4.8e-37 127.4 0.1 5.7e-37 127.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NHS PF15273.1 EEQ27453.1 - 0.056 12.0 0.2 0.063 11.8 0.2 1.1 1 0 0 1 1 1 0 NHS-like Pkinase PF00069.20 EEQ27454.1 - 1.2e-64 217.9 0.0 1.6e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27454.1 - 3.9e-31 108.0 0.0 6.8e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ27454.1 - 3.8e-05 22.8 0.0 6.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ27454.1 - 0.00046 19.2 0.1 0.0021 17.0 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ27454.1 - 0.0053 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family NAD_binding_8 PF13450.1 EEQ27457.1 - 6.2e-09 35.7 0.0 1.5e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EEQ27457.1 - 2.5e-06 26.8 0.0 0.00019 20.6 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EEQ27457.1 - 0.00022 21.3 0.2 0.00046 20.3 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ27457.1 - 0.0051 16.7 0.0 0.048 13.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ27457.1 - 0.049 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EEQ27457.1 - 0.054 12.5 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEQ27457.1 - 0.056 12.4 0.1 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EEQ27457.1 - 0.066 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EEQ27457.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 EEQ27457.1 - 0.19 11.4 0.6 0.9 9.2 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding HNH_2 PF13391.1 EEQ27458.1 - 1.9e-06 27.5 0.1 3.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HTH_41 PF14502.1 EEQ27460.1 - 0.0023 17.4 0.6 0.5 10.0 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain Reo_sigmaC PF04582.7 EEQ27460.1 - 0.0097 15.1 0.3 0.017 14.3 0.2 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Fmp27_WPPW PF10359.4 EEQ27460.1 - 0.011 14.2 0.2 0.016 13.6 0.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4404 PF14357.1 EEQ27460.1 - 0.011 16.1 0.4 0.029 14.7 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) DUF1664 PF07889.7 EEQ27460.1 - 0.022 14.5 1.2 1.3 8.8 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_27 PF13514.1 EEQ27460.1 - 0.036 11.7 0.9 0.063 10.9 0.5 1.4 1 1 0 1 1 1 0 AAA domain VirB8 PF04335.8 EEQ27460.1 - 0.041 13.4 0.1 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 VirB8 protein DUF948 PF06103.6 EEQ27460.1 - 0.059 13.2 0.4 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PspB PF06667.7 EEQ27460.1 - 0.067 13.1 0.1 0.59 10.0 0.0 2.4 3 0 0 3 3 3 0 Phage shock protein B HlyD PF00529.15 EEQ27460.1 - 0.092 12.0 1.3 0.14 11.3 0.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Syntaxin-6_N PF09177.6 EEQ27460.1 - 0.11 12.8 0.8 0.96 9.8 0.2 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DASH_Dad1 PF08649.5 EEQ27460.1 - 0.15 11.7 0.1 0.84 9.3 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad1 Vac_Fusion PF02346.11 EEQ27460.1 - 0.16 11.4 0.4 25 4.3 0.0 2.7 3 0 0 3 3 3 0 Chordopoxvirus fusion protein HisKA_2 PF07568.7 EEQ27460.1 - 0.18 11.7 0.5 6.1 6.7 0.1 2.3 1 1 1 2 2 2 0 Histidine kinase Mnd1 PF03962.10 EEQ27460.1 - 0.18 11.4 0.2 0.44 10.1 0.1 1.5 2 0 0 2 2 2 0 Mnd1 family TPT PF03151.11 EEQ27461.1 - 5.5e-27 94.2 11.8 5.5e-27 94.2 8.2 3.0 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EEQ27461.1 - 8.1e-07 28.2 21.6 1.6e-05 23.9 15.0 2.2 1 1 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 EEQ27461.1 - 0.015 14.1 15.3 0.027 13.3 10.6 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EEQ27461.1 - 0.048 13.7 28.2 0.23 11.5 5.3 3.1 3 1 0 3 3 3 0 EamA-like transporter family TFIIB PF00382.14 EEQ27463.1 - 1.1e-30 105.2 0.5 2.7e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EEQ27463.1 - 3.2e-24 84.9 0.0 3.2e-24 84.9 0.0 3.6 5 0 0 5 5 5 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EEQ27463.1 - 0.00038 19.7 2.6 0.00093 18.4 1.8 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EEQ27463.1 - 0.00099 18.6 0.1 0.53 9.8 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain RRN7 PF11781.3 EEQ27463.1 - 0.032 13.7 0.1 0.069 12.6 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 EEQ27463.1 - 0.34 10.8 3.0 0.65 9.9 2.1 1.4 1 0 0 1 1 1 0 IBR domain E1-E2_ATPase PF00122.15 EEQ27465.1 - 2.1e-53 180.7 0.0 1.4e-52 178.0 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ27465.1 - 1.8e-36 126.5 0.1 3.4e-36 125.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EEQ27465.1 - 1.9e-34 117.6 5.2 3.5e-09 36.6 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EEQ27465.1 - 4.6e-18 66.0 0.0 9.1e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ27465.1 - 0.0001 21.9 1.4 0.0011 18.6 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Acylphosphatase PF00708.13 EEQ27465.1 - 0.11 12.6 0.6 0.79 9.8 0.0 2.7 3 0 0 3 3 3 0 Acylphosphatase ERCC4 PF02732.10 EEQ27466.1 - 2.2e-30 105.2 0.1 4.2e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EEQ27466.1 - 8.7e-05 22.6 0.0 0.0037 17.4 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain Fungal_trans PF04082.13 EEQ27467.1 - 1e-07 31.1 0.8 3.9e-07 29.2 0.6 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ27467.1 - 1.3e-06 28.2 10.5 1.9e-06 27.6 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP3 PF08572.5 EEQ27468.1 - 4.2e-72 242.1 3.8 7e-72 241.4 2.6 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EEQ27468.1 - 5.9e-40 135.9 0.5 5.9e-40 135.9 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 EEQ27469.1 - 9.3e-86 287.5 0.0 5e-85 285.1 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EEQ27469.1 - 1.3e-62 210.6 0.0 3.5e-62 209.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EEQ27469.1 - 4.5e-35 120.7 0.0 7e-34 116.8 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EEQ27469.1 - 8.9e-24 84.3 0.8 2.1e-18 66.6 0.0 3.1 3 1 1 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EEQ27469.1 - 1.4e-17 63.3 0.0 7.1e-17 61.1 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF1227 PF06777.6 EEQ27470.1 - 9.1e-62 207.0 0.8 2.5e-61 205.6 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EEQ27470.1 - 1.3e-50 171.2 0.3 2.7e-50 170.1 0.2 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EEQ27470.1 - 4.6e-45 153.5 0.0 1.3e-44 152.1 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 EEQ27470.1 - 2.4e-05 23.2 0.0 0.00011 21.1 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EEQ27470.1 - 0.00011 21.7 0.0 0.047 13.1 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EEQ27470.1 - 0.00053 19.8 0.8 0.0038 17.0 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EEQ27470.1 - 0.0032 17.0 0.3 0.0032 17.0 0.2 2.0 2 1 0 2 2 2 1 AAA domain OmpH PF03938.9 EEQ27470.1 - 0.0078 16.1 2.1 0.31 10.9 0.0 2.3 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) AAA_19 PF13245.1 EEQ27470.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EEQ27470.1 - 0.089 12.0 0.1 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein zf-RING_2 PF13639.1 EEQ27471.1 - 4e-07 29.7 10.3 8.6e-07 28.6 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEQ27471.1 - 4e-06 26.8 3.1 9.3e-06 25.6 2.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEQ27471.1 - 6.4e-05 22.7 3.8 0.00013 21.6 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EEQ27471.1 - 0.0018 18.1 7.2 0.0041 17.0 5.0 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EEQ27471.1 - 0.0027 17.3 13.4 0.0056 16.3 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ27471.1 - 0.084 12.9 13.0 0.19 11.7 9.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EEQ27471.1 - 0.3 11.1 10.6 0.65 10.0 7.3 1.6 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EEQ27471.1 - 0.43 10.3 8.4 0.13 12.0 3.6 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EEQ27471.1 - 1.2 9.1 9.8 2.7 8.0 6.8 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.1 EEQ27471.1 - 2 8.1 8.0 4.7 6.9 5.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EEQ27471.1 - 2.2 7.9 8.0 4.3 7.0 5.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LCM PF04072.9 EEQ27472.1 - 3.4e-23 82.1 0.0 5.2e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase SUN PF03856.8 EEQ27473.1 - 3.9e-79 265.4 13.9 6.6e-79 264.7 9.6 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) zf-C3HC4_3 PF13920.1 EEQ27474.1 - 0.015 14.9 4.0 0.13 11.9 2.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ27474.1 - 0.05 13.2 2.3 0.39 10.4 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ist1 PF03398.9 EEQ27475.1 - 2e-30 105.3 0.5 2.4e-14 53.0 1.0 2.2 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway DUF2910 PF11139.3 EEQ27476.1 - 0.014 14.5 0.7 0.014 14.5 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2910) Peptidase_S28 PF05577.7 EEQ27478.1 - 3.7e-52 177.3 1.0 6.3e-52 176.6 0.7 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DAHP_synth_2 PF01474.11 EEQ27479.1 - 2.1e-143 477.8 0.0 2.9e-85 286.2 0.0 2.0 1 1 0 2 2 2 2 Class-II DAHP synthetase family Zn_clus PF00172.13 EEQ27480.1 - 4.6e-05 23.2 13.0 4.6e-05 23.2 9.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EEQ27480.1 - 0.08 13.3 9.9 0.25 11.7 6.9 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type AMP-binding PF00501.23 EEQ27481.1 - 4.4e-64 216.4 0.0 5.6e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ27481.1 - 3.3e-05 24.7 0.0 7.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IFT20 PF14931.1 EEQ27481.1 - 0.06 13.2 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Clat_adaptor_s PF01217.15 EEQ27482.1 - 1.7e-54 183.4 2.3 2e-54 183.1 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.15 EEQ27484.1 - 4.4e-17 62.4 0.3 7.4e-17 61.7 0.2 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.11 EEQ27485.1 - 1.7e-30 104.6 0.4 1.9e-29 101.2 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Aminotran_1_2 PF00155.16 EEQ27486.1 - 4e-64 216.8 0.0 4.7e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEQ27486.1 - 0.004 15.4 0.0 0.007 14.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EEQ27486.1 - 0.043 12.5 0.0 0.083 11.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Mmp37 PF09139.6 EEQ27488.1 - 1.2e-136 455.0 0.0 1.5e-136 454.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 BIR PF00653.16 EEQ27489.1 - 3e-24 85.1 0.8 1.8e-21 76.3 0.0 3.3 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.3 EEQ27490.1 - 1.9e-07 31.0 0.3 3.5e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ27490.1 - 2.9e-06 27.2 0.5 7.5e-06 25.9 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EEQ27490.1 - 0.0023 18.1 0.4 0.0046 17.2 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EEQ27490.1 - 0.095 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) EVC2_like PF12297.3 EEQ27490.1 - 0.22 10.0 5.9 0.34 9.4 4.1 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein RNA_polI_A34 PF08208.6 EEQ27490.1 - 6.5 6.3 15.6 0.12 12.0 3.8 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3381 PF11861.3 EEQ27490.1 - 7.5 6.0 15.1 1.3 8.5 6.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) F-box-like PF12937.2 EEQ27491.1 - 4.6e-05 23.0 0.3 8.5e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ27491.1 - 0.00063 19.3 0.1 0.0013 18.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain AMP-binding PF00501.23 EEQ27492.1 - 1.3e-46 158.8 0.0 1.9e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ27492.1 - 0.00019 22.2 0.0 0.00054 20.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 EEQ27494.1 - 3.1e-24 85.5 0.0 4.2e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27494.1 - 7.7e-06 25.1 0.1 0.00021 20.4 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Tox-MPTase5 PF15641.1 EEQ27495.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Metallopeptidase toxin 5 RNA_pol_Rpb5_C PF01191.14 EEQ27497.1 - 5.5e-35 118.8 0.2 8.8e-35 118.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EEQ27497.1 - 7.1e-30 103.2 0.0 1.2e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EEQ27497.1 - 0.00075 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease DUF2968 PF11180.3 EEQ27498.1 - 0.0021 17.5 11.3 0.0021 17.5 7.8 4.6 2 1 3 5 5 5 2 Protein of unknown function (DUF2968) APG6 PF04111.7 EEQ27498.1 - 0.0037 16.3 19.5 0.0037 16.3 13.5 3.2 2 1 1 3 3 3 2 Autophagy protein Apg6 IncA PF04156.9 EEQ27498.1 - 0.083 12.4 51.3 0.073 12.6 11.9 4.1 2 1 0 3 3 3 0 IncA protein Helicase_IV_N PF12462.3 EEQ27498.1 - 0.1 12.2 0.1 0.1 12.2 0.1 3.5 3 0 0 3 3 3 0 DNA helicase IV / RNA helicase N terminal KxDL PF10241.4 EEQ27498.1 - 0.26 11.2 15.0 0.45 10.4 0.1 4.3 2 1 2 4 4 4 0 Uncharacterized conserved protein Spectrin PF00435.16 EEQ27498.1 - 1.6 9.0 36.9 0.082 13.1 5.8 3.9 3 2 0 3 3 3 0 Spectrin repeat Occludin_ELL PF07303.8 EEQ27498.1 - 1.6 9.5 37.5 0.39 11.4 8.1 4.4 2 1 3 5 5 5 0 Occludin homology domain Baculo_PEP_C PF04513.7 EEQ27498.1 - 3.1 7.6 18.2 1.1 9.1 2.4 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4140 PF13600.1 EEQ27498.1 - 3.5 8.1 44.5 1.1 9.7 0.3 6.6 2 1 4 7 7 7 0 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.4 EEQ27498.1 - 5.2 6.9 45.5 0.47 10.2 14.1 3.9 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EEQ27498.1 - 7 6.4 22.7 1.8 8.3 2.6 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) MscS_porin PF12795.2 EEQ27498.1 - 7.1 5.8 51.1 0.37 10.0 10.9 3.7 3 1 0 3 3 3 0 Mechanosensitive ion channel porin domain CYSTM PF12734.2 EEQ27499.1 - 1.3e-10 41.1 14.6 1.3e-10 41.1 10.1 4.2 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Nol1_Nop2_Fmu PF01189.12 EEQ27500.1 - 0.0032 16.8 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Hex_IIIa PF02455.11 EEQ27500.1 - 0.15 10.7 1.6 1.6 7.3 1.0 2.0 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) Abhydrolase_3 PF07859.8 EEQ27501.1 - 7.7e-35 120.3 0.0 1.3e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Nol1_Nop2_Fmu PF01189.12 EEQ27501.1 - 8e-12 45.1 0.0 2.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family Thioesterase PF00975.15 EEQ27501.1 - 0.0019 18.4 0.0 0.0042 17.3 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EEQ27501.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 EEQ27501.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2974 PF11187.3 EEQ27501.1 - 0.18 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PLAC8 PF04749.12 EEQ27502.1 - 2.4e-14 53.7 4.0 2.7e-07 31.0 0.2 2.1 1 1 1 2 2 2 2 PLAC8 family Aldolase_II PF00596.16 EEQ27503.1 - 3.7e-44 150.5 0.1 4.8e-44 150.1 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DEAD PF00270.24 EEQ27504.1 - 2.3e-40 137.8 0.1 3.3e-40 137.3 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ27504.1 - 3e-19 68.6 0.4 6.1e-19 67.6 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ27504.1 - 0.0081 16.0 0.2 0.016 15.0 0.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EEQ27504.1 - 0.039 13.2 0.2 0.084 12.1 0.1 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain Ank_2 PF12796.2 EEQ27505.1 - 1.4e-47 159.9 31.9 8.9e-10 38.7 0.0 11.9 5 4 6 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ27505.1 - 9.3e-34 113.5 39.8 0.0024 17.5 0.0 18.5 18 2 0 18 18 18 11 Ankyrin repeat Ank_4 PF13637.1 EEQ27505.1 - 1.3e-20 73.3 19.5 0.0039 17.6 0.0 13.6 13 3 1 14 14 14 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ27505.1 - 2.1e-15 56.3 17.9 0.089 13.0 0.0 11.7 12 2 2 14 14 14 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ27505.1 - 2.4e-14 52.0 18.2 6.8 7.2 0.0 17.5 20 1 1 21 21 21 4 Ankyrin repeat Adenylsucc_synt PF00709.16 EEQ27506.1 - 3.5e-156 520.1 0.0 3.9e-156 519.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.26 EEQ27507.1 - 1.2e-21 76.2 1.4 2.3e-21 75.2 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 EEQ27508.1 - 8.1e-30 103.5 0.0 2.6e-29 101.8 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ27508.1 - 3.1e-08 33.3 13.3 4.9e-08 32.7 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EEQ27508.1 - 0.26 10.6 29.7 0.13 11.6 15.2 2.4 2 0 0 2 2 2 0 Vta1 like Homeobox_KN PF05920.6 EEQ27510.1 - 1.7e-14 53.2 0.3 4.8e-14 51.7 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.21 EEQ27510.1 - 5.5e-05 23.2 25.3 0.012 15.8 1.1 5.0 3 1 1 4 4 4 3 Zinc finger, C2H2 type HTH_Tnp_Tc5 PF03221.11 EEQ27510.1 - 6.4e-05 22.6 0.0 0.00022 20.9 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.1 EEQ27510.1 - 7.5e-05 22.7 29.6 0.0011 19.1 1.1 5.3 5 0 0 5 5 5 2 C2H2-type zinc finger Homeobox PF00046.24 EEQ27510.1 - 0.0015 18.1 0.0 0.0042 16.6 0.0 1.8 1 0 0 1 1 1 1 Homeobox domain HA PF03457.9 EEQ27510.1 - 0.011 15.7 0.6 0.049 13.7 0.0 2.4 3 0 0 3 3 3 0 Helicase associated domain Elf1 PF05129.8 EEQ27510.1 - 1 9.0 5.0 2.3 7.9 1.8 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Cupin_8 PF13621.1 EEQ27512.1 - 2.3e-34 119.0 0.0 6.4e-34 117.5 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EEQ27512.1 - 3e-06 26.7 0.0 0.001 18.3 0.0 2.5 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.17 EEQ27512.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase PLA2_B PF01735.13 EEQ27512.1 - 0.056 11.6 0.0 0.089 10.9 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain 2OG-FeII_Oxy_2 PF13532.1 EEQ27513.1 - 1.9e-34 119.2 0.1 2.5e-34 118.8 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 EEQ27513.1 - 1.7e-05 24.1 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain zf-GRF PF06839.7 EEQ27513.1 - 0.0017 18.2 8.5 0.0035 17.2 5.9 1.5 1 0 0 1 1 1 1 GRF zinc finger Lipoprotein_15 PF03640.10 EEQ27513.1 - 0.091 12.2 0.1 2.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Secreted repeat of unknown function UQ_con PF00179.21 EEQ27515.1 - 3.7e-10 39.3 0.1 6.4e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEQ27515.1 - 0.018 14.9 0.1 0.036 13.9 0.1 1.6 1 0 0 1 1 1 0 RWD domain GTP1_OBG PF01018.17 EEQ27516.1 - 1.3e-34 119.0 2.1 4.4e-25 88.1 1.9 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EEQ27516.1 - 9.7e-22 77.1 0.0 2.4e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ27516.1 - 8.2e-08 31.6 0.0 1.7e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEQ27516.1 - 0.016 15.0 0.0 6.9 6.4 0.0 2.4 1 1 1 2 2 2 0 Dynamin family ArgK PF03308.11 EEQ27516.1 - 0.023 13.5 0.0 0.25 10.1 0.0 2.1 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 EEQ27516.1 - 0.052 13.8 1.4 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter YXWGXW PF12779.2 EEQ27518.1 - 0.46 10.4 2.3 0.79 9.6 1.6 1.4 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) MFS_1 PF07690.11 EEQ27519.1 - 2e-34 118.9 13.5 4.9e-32 111.0 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ27519.1 - 4.1e-11 42.1 2.2 4.1e-11 42.1 1.5 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter Nuc_H_symport PF03825.11 EEQ27519.1 - 0.00058 18.7 1.1 0.00058 18.7 0.7 1.8 2 0 0 2 2 2 1 Nucleoside H+ symporter Abhydrolase_6 PF12697.2 EEQ27520.1 - 3.1e-30 105.7 0.4 4e-30 105.3 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ27520.1 - 8.3e-08 32.0 0.1 1.4e-07 31.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FLYWCH_N PF15423.1 EEQ27520.1 - 0.1 12.7 0.0 17 5.6 0.0 2.3 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein WD40 PF00400.27 EEQ27521.1 - 4.2e-25 86.6 19.1 5.7e-08 32.3 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EEQ27521.1 - 0.0043 16.7 0.0 0.047 13.3 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF1518 PF07469.7 EEQ27521.1 - 0.28 11.3 4.0 0.26 11.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) DUF1014 PF06244.7 EEQ27522.1 - 9.9e-25 87.1 13.1 3.9e-24 85.2 9.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) F-box-like PF12937.2 EEQ27523.1 - 3.3e-07 29.9 0.2 7e-07 28.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ27523.1 - 5.9e-07 28.9 2.3 1.1e-06 28.1 0.4 2.5 2 0 0 2 2 2 1 F-box domain Peptidase_C13 PF01650.13 EEQ27524.1 - 4.7e-41 140.7 0.0 6.5e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family CDC45 PF02724.9 EEQ27525.1 - 1e-233 776.9 0.0 1.8e-233 776.1 0.0 1.7 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.5 EEQ27525.1 - 0.11 11.5 33.5 0.066 12.2 5.3 2.1 2 0 0 2 2 2 0 BUD22 Trypan_PARP PF05887.6 EEQ27525.1 - 0.24 11.2 4.7 0.86 9.4 2.4 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DDRGK PF09756.4 EEQ27525.1 - 0.47 9.8 14.7 0.88 8.9 10.2 1.3 1 0 0 1 1 1 0 DDRGK domain DUF1510 PF07423.6 EEQ27525.1 - 4.2 6.6 14.8 0.17 11.2 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FAM60A PF15396.1 EEQ27525.1 - 9.9 5.8 10.1 0.15 11.8 1.3 1.9 2 0 0 2 2 2 0 Protein Family FAM60A Ank_2 PF12796.2 EEQ27526.1 - 1.7e-144 470.5 2.9 1.7e-22 79.5 0.0 9.9 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ27526.1 - 3.5e-139 446.2 17.3 1.5e-09 37.1 0.0 19.5 19 0 0 19 19 19 18 Ankyrin repeat Ank_3 PF13606.1 EEQ27526.1 - 6.4e-96 304.5 4.8 1.2e-05 25.0 0.0 19.0 18 0 0 18 18 18 17 Ankyrin repeat Ank_5 PF13857.1 EEQ27526.1 - 8.9e-96 311.7 25.5 7.2e-10 38.7 0.0 15.9 3 3 13 16 16 16 16 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ27526.1 - 1.5e-91 299.3 10.9 6.8e-12 45.5 0.0 12.6 6 3 4 12 12 12 11 Ankyrin repeats (many copies) NACHT PF05729.7 EEQ27526.1 - 1.2e-08 34.8 0.0 3.2e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEQ27526.1 - 2.3e-08 34.2 0.0 5.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ27526.1 - 8.3e-06 25.9 0.0 3.8e-05 23.8 0.0 2.2 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 EEQ27526.1 - 1.9e-05 24.5 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EEQ27526.1 - 0.00043 20.4 0.0 0.0022 18.2 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEQ27526.1 - 0.0016 18.1 0.0 0.005 16.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EEQ27526.1 - 0.021 15.0 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter cobW PF02492.14 EEQ27526.1 - 0.03 13.7 0.0 0.094 12.1 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EEQ27526.1 - 0.055 13.6 0.1 0.16 12.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.1 EEQ27526.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ27526.1 - 0.08 13.7 0.3 0.66 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EEQ27526.1 - 0.084 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GATase_7 PF13537.1 EEQ27526.1 - 0.093 12.4 0.0 7.6 6.2 0.0 3.5 3 1 1 4 4 3 0 Glutamine amidotransferase domain UPF0079 PF02367.12 EEQ27526.1 - 0.094 12.3 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EEQ27526.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 NTPase PIF1 PF05970.9 EEQ27526.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.17 EEQ27526.1 - 0.14 10.9 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.13 EEQ27526.1 - 0.22 11.0 0.2 0.56 9.6 0.0 1.7 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase HeLo PF14479.1 EEQ27527.1 - 7.7e-54 182.6 3.6 1.1e-53 182.0 2.5 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Syntaxin-6_N PF09177.6 EEQ27527.1 - 0.0015 18.8 1.6 0.0051 17.1 0.2 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF848 PF05852.6 EEQ27527.1 - 0.02 14.7 2.8 2.7 7.8 0.1 2.4 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FliJ PF02050.11 EEQ27527.1 - 0.24 11.4 4.4 0.077 13.0 0.7 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein TPR_10 PF13374.1 EEQ27528.1 - 1.9e-16 59.3 0.5 3.9e-07 29.7 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ27528.1 - 2.4e-16 59.4 1.3 1.9e-07 30.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 EEQ27528.1 - 1e-07 31.1 0.0 2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EEQ27528.1 - 9.8e-07 28.5 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EEQ27528.1 - 0.0002 21.5 0.0 0.00072 19.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain TPR_16 PF13432.1 EEQ27528.1 - 0.0017 18.9 0.1 0.061 14.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ27528.1 - 0.0032 17.9 0.9 0.53 11.0 0.0 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ27528.1 - 0.0035 17.6 1.7 4.4 7.7 0.3 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat AAA_25 PF13481.1 EEQ27528.1 - 0.006 16.0 0.0 0.024 14.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain TPR_17 PF13431.1 EEQ27528.1 - 0.02 15.0 1.2 4.2 7.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ27528.1 - 0.025 14.9 3.5 6.9 7.4 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ27528.1 - 0.055 13.2 0.3 7.2 6.6 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ27528.1 - 0.061 13.1 2.5 1.1 9.2 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 EEQ27528.1 - 0.075 12.7 0.0 1.1 8.8 0.0 2.4 1 1 0 1 1 1 0 Archaeal ATPase TPR_1 PF00515.23 EEQ27528.1 - 0.1 12.2 1.3 7.6 6.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ27528.1 - 0.11 12.4 1.2 11 6.1 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_16 PF13191.1 EEQ27528.1 - 0.14 12.1 2.4 8.9 6.2 0.4 3.3 2 1 0 2 2 2 0 AAA ATPase domain DUF3366 PF11846.3 EEQ27528.1 - 0.32 10.8 2.0 19 5.0 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3366) DUF2508 PF10704.4 EEQ27528.1 - 0.74 10.0 4.0 80 3.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) TPR_3 PF07720.7 EEQ27528.1 - 1.2 9.0 5.2 1.7 8.5 1.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 EEQ27529.1 - 3.9e-08 33.2 0.0 6.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ27529.1 - 5.8e-06 26.3 0.0 9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ27529.1 - 6.4e-05 23.0 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ27529.1 - 0.0029 17.3 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EEQ27529.1 - 0.03 14.1 0.1 8 6.3 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Ndufs5 PF10200.4 EEQ27531.1 - 0.016 15.1 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa AA_permease_2 PF13520.1 EEQ27532.1 - 7.3e-40 136.7 45.4 1e-39 136.3 31.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ27532.1 - 6.8e-22 77.4 40.2 1.3e-21 76.5 27.8 1.3 1 1 0 1 1 1 1 Amino acid permease YlaH PF14036.1 EEQ27532.1 - 0.0044 17.0 5.3 0.005 16.9 2.0 2.4 2 0 0 2 2 2 1 YlaH-like protein CBM_19 PF03427.8 EEQ27532.1 - 0.066 12.9 0.6 0.21 11.3 0.4 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) DUF1129 PF06570.6 EEQ27532.1 - 6.5 5.9 16.0 0.64 9.2 2.4 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) Acetyltransf_3 PF13302.1 EEQ27533.1 - 9.6e-18 64.7 0.0 2.1e-17 63.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ27533.1 - 1.1e-09 38.1 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EEQ27533.1 - 5.1e-05 23.2 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ27533.1 - 9.3e-05 22.3 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ27533.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Glyco_hydro_47 PF01532.15 EEQ27535.1 - 1.6e-136 455.6 0.0 1.8e-136 455.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Histidinol_dh PF00815.15 EEQ27537.1 - 9.2e-179 594.3 5.0 1.5e-178 593.6 3.5 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EEQ27537.1 - 3.1e-25 87.5 0.1 6.8e-25 86.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EEQ27537.1 - 1e-10 41.7 0.4 5.1e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EEQ27537.1 - 0.051 13.5 1.0 0.12 12.3 0.2 2.0 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain RHH_3 PF12651.2 EEQ27537.1 - 0.95 9.2 3.0 0.72 9.6 0.1 2.3 3 0 0 3 3 3 0 Ribbon-helix-helix domain Utp11 PF03998.8 EEQ27538.1 - 2.7e-54 184.5 24.0 3.1e-54 184.3 16.7 1.0 1 0 0 1 1 1 1 Utp11 protein AAA PF00004.24 EEQ27538.1 - 0.081 13.1 0.2 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cmc1 PF08583.5 EEQ27539.1 - 1e-14 54.0 5.1 1.7e-14 53.2 3.3 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like TFIID-31kDa PF02291.10 EEQ27540.1 - 1.9e-29 102.0 0.0 5.3e-23 81.2 0.0 2.9 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Sorb PF02208.11 EEQ27540.1 - 0.061 12.7 0.5 0.14 11.5 0.4 1.5 1 0 0 1 1 1 0 Sorbin homologous domain LNS2 PF08235.8 EEQ27541.1 - 1.3e-70 236.0 0.0 2.2e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EEQ27541.1 - 3.9e-40 135.9 0.0 1.2e-39 134.3 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EEQ27541.1 - 0.015 14.7 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.16 EEQ27543.1 - 0.002 18.1 0.0 0.0054 16.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Thg1C PF14413.1 EEQ27544.1 - 4.5e-52 174.8 4.6 6.1e-52 174.4 3.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EEQ27544.1 - 1.7e-47 160.4 0.1 2.9e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase AAA_21 PF13304.1 EEQ27545.1 - 0.27 11.1 2.4 0.26 11.2 0.8 1.4 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpb1_1 PF04997.7 EEQ27546.1 - 2e-117 392.2 0.0 3.2e-117 391.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EEQ27546.1 - 6.5e-106 353.6 0.0 1.3e-105 352.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EEQ27546.1 - 1.1e-68 230.4 0.0 2.5e-68 229.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EEQ27546.1 - 8e-65 218.0 0.9 1.7e-64 217.0 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EEQ27546.1 - 2.5e-47 160.5 0.0 6.1e-47 159.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EEQ27546.1 - 3.4e-42 143.3 6.1 3.4e-42 143.3 4.3 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EEQ27546.1 - 5.7e-38 128.9 0.2 1.2e-37 127.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EEQ27546.1 - 4.9e-09 35.5 201.9 0.031 14.3 7.1 15.1 12 2 2 15 15 15 12 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 EEQ27547.1 - 1.4e-05 24.7 0.3 0.29 11.0 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Methyltransf_23 PF13489.1 EEQ27548.1 - 2.2e-17 63.2 0.0 3.3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ27548.1 - 3.1e-06 27.7 0.0 8.3e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27548.1 - 1.8e-05 25.1 0.0 5.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ27548.1 - 2.5e-05 24.6 0.0 7.9e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ27548.1 - 4.6e-05 23.0 0.0 0.00012 21.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ27548.1 - 0.00017 20.7 0.0 0.0004 19.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EEQ27548.1 - 0.00082 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EEQ27548.1 - 0.0024 17.0 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EEQ27548.1 - 0.0026 17.7 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EEQ27548.1 - 0.0046 17.3 0.0 0.021 15.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EEQ27548.1 - 0.0046 16.1 0.0 0.024 13.8 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_16 PF10294.4 EEQ27548.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EEQ27548.1 - 0.02 14.9 0.0 0.029 14.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ27548.1 - 0.051 12.6 0.0 0.59 9.1 0.0 2.3 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EEQ27548.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glycos_transf_1 PF00534.15 EEQ27549.1 - 1.8e-15 56.8 0.0 1.7e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEQ27549.1 - 1.8e-05 24.8 0.0 0.0001 22.4 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEQ27549.1 - 0.0011 18.6 0.0 0.0032 17.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 60KD_IMP PF02096.15 EEQ27550.1 - 3.3e-18 66.0 1.5 4.3e-18 65.6 1.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein FA_desaturase PF00487.19 EEQ27550.1 - 0.21 10.9 3.6 0.13 11.6 0.4 1.9 2 0 0 2 2 2 0 Fatty acid desaturase PP2C PF00481.16 EEQ27551.1 - 8.1e-40 136.8 0.0 1.3e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEQ27551.1 - 0.00015 21.2 0.0 0.00035 20.0 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EEQ27551.1 - 0.0075 15.9 0.0 0.43 10.2 0.0 2.8 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.9 EEQ27552.1 - 2.9e-89 299.5 0.1 4.8e-89 298.8 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_11 PF13414.1 EEQ27552.1 - 0.0023 17.5 0.1 0.46 10.1 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EEQ27552.1 - 0.0024 17.6 0.0 0.1 12.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ27552.1 - 0.019 15.5 0.0 11 6.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ27552.1 - 0.021 15.4 0.0 29 5.6 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Nop53 PF07767.6 EEQ27552.1 - 0.03 13.3 9.9 0.051 12.5 6.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TPR_1 PF00515.23 EEQ27552.1 - 0.067 12.8 0.0 0.22 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Cut8_N PF14482.1 EEQ27552.1 - 0.11 12.5 6.7 0.33 10.9 4.6 1.8 1 0 0 1 1 1 0 Cut8 proteasome-binding domain NST1 PF13945.1 EEQ27552.1 - 0.79 9.7 7.2 1.6 8.7 5.0 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Herpes_DNAp_acc PF04929.7 EEQ27552.1 - 9.4 5.0 10.1 17 4.2 7.0 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PQ-loop PF04193.9 EEQ27553.1 - 1e-39 133.8 6.0 1.3e-20 72.6 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat Ribosomal_60s PF00428.14 EEQ27554.1 - 4.2e-25 87.9 6.7 5.2e-25 87.6 4.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 EEQ27555.1 - 8.3e-54 181.3 0.0 2.9e-32 111.5 0.0 4.6 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.7 EEQ27555.1 - 0.059 13.2 0.5 0.23 11.2 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 EEQ27555.1 - 0.21 12.0 1.2 1 9.8 0.1 2.7 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Aconitase PF00330.15 EEQ27556.1 - 4.9e-156 519.8 0.0 2.2e-155 517.6 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEQ27556.1 - 5.9e-41 139.6 0.0 9.5e-41 138.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain HEAT_2 PF13646.1 EEQ27557.1 - 7.4e-23 80.6 10.3 2.2e-05 24.6 0.0 9.0 6 2 3 9 9 9 6 HEAT repeats HEAT PF02985.17 EEQ27557.1 - 2.7e-19 67.4 13.2 0.001 18.9 0.0 11.0 13 0 0 13 13 11 5 HEAT repeat HEAT_EZ PF13513.1 EEQ27557.1 - 7.1e-18 64.5 18.0 1.3e-06 28.6 0.2 9.9 8 2 2 10 10 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ27557.1 - 6.9e-10 39.1 0.0 0.023 15.0 0.0 6.0 3 2 2 5 5 5 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EEQ27557.1 - 8e-07 28.6 0.1 0.12 11.6 0.0 5.4 4 1 1 5 5 5 1 CLASP N terminal RIX1 PF08167.7 EEQ27557.1 - 3.5e-06 26.8 0.0 0.047 13.3 0.0 4.4 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EEQ27557.1 - 1.7e-05 23.7 0.3 0.037 12.7 0.0 4.6 4 2 1 5 5 5 1 RNAPII transcription regulator C-terminal Arm PF00514.18 EEQ27557.1 - 5.5e-05 22.8 2.8 2.6 7.9 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EEQ27557.1 - 0.00025 19.4 1.8 0.0041 15.4 0.1 3.3 3 1 0 4 4 4 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 EEQ27557.1 - 0.00045 18.6 0.6 0.0022 16.3 0.0 2.4 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit DUF3385 PF11865.3 EEQ27557.1 - 0.00057 19.8 2.2 17 5.2 0.0 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) IBN_N PF03810.14 EEQ27557.1 - 0.00067 19.5 0.5 0.006 16.4 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.2 EEQ27557.1 - 0.0012 18.6 0.4 0.28 11.0 0.0 4.4 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.1 EEQ27557.1 - 0.014 14.8 3.2 12 5.2 0.0 5.1 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) V-ATPase_H_N PF03224.9 EEQ27557.1 - 0.019 14.0 1.9 0.2 10.7 0.0 3.2 3 1 0 3 3 3 0 V-ATPase subunit H CBS PF00571.23 EEQ27558.1 - 1.1e-41 140.3 7.5 1.1e-10 41.0 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EEQ27558.1 - 2e-09 36.9 0.0 8e-09 35.0 0.0 2.1 2 0 0 2 2 2 1 PB1 domain DUF3235 PF11574.3 EEQ27558.1 - 0.16 12.1 1.2 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Ribosomal_S26e PF01283.14 EEQ27559.1 - 4.9e-50 168.5 8.2 5.9e-50 168.2 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 EEQ27559.1 - 0.038 14.3 0.2 8.7 6.7 0.0 2.4 1 1 1 2 2 2 0 Putative zinc ribbon domain F-box-like PF12937.2 EEQ27560.1 - 0.00013 21.6 0.2 0.0004 20.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EEQ27560.1 - 0.00023 20.9 0.5 6.2 7.2 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 EEQ27560.1 - 0.00085 18.8 2.6 12 5.6 0.0 5.3 4 2 1 5 5 5 1 Leucine Rich repeats (2 copies) F-box PF00646.28 EEQ27560.1 - 0.12 12.1 2.0 0.15 11.7 0.3 2.1 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.28 EEQ27560.1 - 1.7 8.9 6.9 18 5.8 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Sulfotransfer_3 PF13469.1 EEQ27561.1 - 1.9e-05 25.6 0.3 2.8e-05 25.0 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase family Peptidase_C14 PF00656.17 EEQ27562.1 - 6.3e-69 232.4 0.0 8.6e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EEQ27562.1 - 1.2 8.9 0.0 1.2 8.9 0.0 2.8 4 0 0 4 4 4 0 Raptor N-terminal CASPase like domain Cpn60_TCP1 PF00118.19 EEQ27563.1 - 4.1e-143 477.5 4.5 4.8e-143 477.3 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 EEQ27563.1 - 0.12 12.1 0.3 0.46 10.3 0.1 2.0 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) zf-H2C2 PF09337.5 EEQ27564.1 - 1.2e-21 75.7 4.3 1.2e-21 75.7 3.0 1.9 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger DUF367 PF04034.8 EEQ27565.1 - 1.8e-46 156.8 0.0 2.7e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EEQ27565.1 - 2.7e-09 36.4 0.4 4.2e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF1293 PF06950.6 EEQ27565.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) VHS PF00790.14 EEQ27567.1 - 1.2e-44 151.3 0.0 5.8e-44 149.1 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EEQ27567.1 - 5e-25 87.4 0.8 5e-25 87.4 0.5 2.2 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EEQ27567.1 - 4.4e-18 65.6 0.4 1.2e-17 64.3 0.3 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain MCM PF00493.18 EEQ27569.1 - 7.3e-135 449.0 0.0 1.1e-134 448.4 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EEQ27569.1 - 1.8e-30 106.0 31.1 1.8e-30 106.0 21.6 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EEQ27569.1 - 4.8e-18 65.7 0.1 1.2e-17 64.5 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ27569.1 - 1.6e-07 30.6 0.1 9.8e-06 24.8 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ27569.1 - 8.5e-06 25.5 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEQ27569.1 - 0.00076 19.0 0.0 0.0062 16.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEQ27569.1 - 0.006 16.0 0.2 0.099 12.1 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-UBR PF02207.15 EEQ27570.1 - 8.3e-16 57.4 6.2 8.3e-16 57.4 4.3 4.0 4 0 0 4 4 4 3 Putative zinc finger in N-recognin (UBR box) Na_H_Exchanger PF00999.16 EEQ27571.1 - 5.9e-08 31.6 14.4 5.4e-07 28.4 3.8 3.6 3 1 0 3 3 3 2 Sodium/hydrogen exchanger family YtpI PF14007.1 EEQ27571.1 - 0.044 13.6 0.3 0.21 11.5 0.1 2.2 2 0 0 2 2 2 0 YtpI-like protein Pkinase PF00069.20 EEQ27572.1 - 9.2e-65 218.3 0.0 1.1e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27572.1 - 7.4e-31 107.1 0.0 1.1e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ27572.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EEQ27572.1 - 0.084 12.5 0.0 0.66 9.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Zn_clus PF00172.13 EEQ27573.1 - 0.00033 20.4 7.4 0.0006 19.6 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2639 PF11121.3 EEQ27573.1 - 0.088 12.3 0.0 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2639) ADH_zinc_N PF00107.21 EEQ27574.1 - 1.4e-11 44.0 0.0 2.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ27574.1 - 1.2e-06 28.2 1.8 3.4e-06 26.7 1.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain UvdE PF03851.9 EEQ27576.1 - 1.1e-30 106.5 0.0 4.5e-21 75.0 0.0 2.1 2 0 0 2 2 2 2 UV-endonuclease UvdE AMP-binding PF00501.23 EEQ27577.1 - 3.9e-81 272.5 0.0 5.8e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EEQ27577.1 - 1.2e-72 244.4 0.0 2.7e-72 243.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEQ27577.1 - 2.9e-51 173.7 0.0 6.8e-50 169.2 0.0 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EEQ27577.1 - 1.7e-46 159.0 0.0 3.6e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EEQ27577.1 - 1.3e-44 152.5 0.0 1.9e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EEQ27577.1 - 5e-41 140.3 0.0 4.3e-38 130.8 0.0 3.0 3 0 0 3 3 2 1 short chain dehydrogenase Condensation PF00668.15 EEQ27577.1 - 6.9e-40 136.7 0.0 1.1e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 EEQ27577.1 - 3.2e-32 110.8 0.0 8.4e-32 109.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EEQ27577.1 - 9.6e-30 103.3 0.0 2.2e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EEQ27577.1 - 3.1e-19 69.3 0.0 3e-18 66.1 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EEQ27577.1 - 1.6e-14 53.8 0.5 4.2e-07 30.1 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EEQ27577.1 - 6.1e-12 45.6 0.0 1.6e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_23 PF13489.1 EEQ27577.1 - 2.3e-11 43.7 0.0 1.1e-10 41.4 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ27577.1 - 9.2e-11 42.3 0.0 1.3e-09 38.6 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27577.1 - 4.6e-10 39.8 0.0 1.8e-09 37.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EEQ27577.1 - 3.8e-09 36.3 0.0 3.6e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EEQ27577.1 - 1.3e-07 31.2 0.0 7.2e-07 28.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 EEQ27577.1 - 9.9e-07 27.9 0.1 2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EEQ27577.1 - 1.2e-05 24.5 0.0 3.3e-05 23.1 0.0 1.7 2 0 0 2 2 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EEQ27577.1 - 5.5e-05 23.4 0.0 0.00026 21.3 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ27577.1 - 0.00092 18.7 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase AMP-binding_C PF13193.1 EEQ27577.1 - 0.017 16.0 0.0 0.18 12.7 0.0 2.9 3 0 0 3 3 1 0 AMP-binding enzyme C-terminal domain RrnaAD PF00398.15 EEQ27577.1 - 0.1 11.5 0.0 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Shikimate_DH PF01488.15 EEQ27577.1 - 0.11 12.6 0.0 5.1 7.2 0.0 2.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AATase PF07247.7 EEQ27577.1 - 0.13 10.8 0.0 0.29 9.6 0.0 1.5 1 0 0 1 1 1 0 Alcohol acetyltransferase Post_transc_reg PF13797.1 EEQ27577.1 - 0.24 11.0 0.0 0.55 9.8 0.0 1.5 1 0 0 1 1 1 0 Post-transcriptional regulator Sugar_tr PF00083.19 EEQ27578.1 - 4.9e-86 289.0 21.1 8.2e-86 288.3 14.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ27578.1 - 1.1e-37 129.6 70.5 2.9e-31 108.4 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MIS13 PF08202.6 EEQ27579.1 - 3.6e-15 55.8 24.5 2e-11 43.5 2.3 3.7 2 1 1 3 3 3 2 Mis12-Mtw1 protein family TSNR_N PF04705.7 EEQ27579.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Thiostrepton-resistance methylase, N terminus DivIC PF04977.10 EEQ27579.1 - 0.11 11.9 0.2 0.34 10.4 0.1 1.8 1 0 0 1 1 1 0 Septum formation initiator TMEM237 PF15383.1 EEQ27579.1 - 2.9 6.9 4.1 5 6.1 2.8 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 RPN7 PF10602.4 EEQ27580.1 - 6.6e-54 181.9 0.3 1e-53 181.3 0.2 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EEQ27580.1 - 1.9e-12 47.4 0.0 3.6e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EEQ27580.1 - 0.12 12.2 2.5 0.23 11.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 EEQ27581.1 - 4.5e-40 137.7 0.0 6.2e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PEPCK_ATP PF01293.15 EEQ27583.1 - 1.4e-217 722.8 0.0 1.7e-217 722.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EEQ27583.1 - 0.049 13.9 0.0 13 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEQ27583.1 - 0.063 13.1 0.1 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EEQ27583.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Sugar_tr PF00083.19 EEQ27585.1 - 1.8e-30 105.9 26.7 9.8e-28 96.9 18.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ27585.1 - 1e-19 70.4 61.0 6.3e-19 67.9 25.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PEX11 PF05648.9 EEQ27586.1 - 2.8e-69 232.7 0.1 3.2e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Amidase PF01425.16 EEQ27587.1 - 1.7e-68 231.4 0.2 3.6e-67 227.1 0.1 2.0 1 1 0 1 1 1 1 Amidase ARID PF01388.16 EEQ27588.1 - 2.4e-09 36.9 0.0 4.2e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF4066 PF13278.1 EEQ27589.1 - 5.9e-12 45.1 0.0 7.2e-12 44.8 0.0 1.3 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEQ27589.1 - 4.1e-09 36.0 0.1 5.6e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GPI-anchored PF10342.4 EEQ27590.1 - 2.1e-12 47.3 0.7 3.9e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ArfGap PF01412.13 EEQ27591.1 - 9.3e-40 135.0 2.4 1.5e-39 134.3 1.7 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 EEQ27592.1 - 4.1e-49 165.4 0.1 5.3e-49 165.0 0.1 1.1 1 0 0 1 1 1 1 SelR domain NinF PF05810.7 EEQ27592.1 - 0.0027 17.4 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 1 NinF protein DZR PF12773.2 EEQ27592.1 - 0.13 12.0 3.3 5.9 6.8 2.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.9 EEQ27592.1 - 0.21 11.6 1.3 1.8 8.6 0.8 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1771 PF08590.5 EEQ27593.1 - 3.8e-11 42.8 4.9 1.1e-10 41.3 3.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EEQ27593.1 - 1.8e-10 40.8 0.1 5.1e-10 39.3 0.1 1.8 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 EEQ27593.1 - 2.9e-09 36.2 1.1 2.6e-08 33.1 0.1 2.9 3 0 0 3 3 3 1 CUE domain UBA PF00627.26 EEQ27593.1 - 0.0041 16.9 1.2 0.059 13.2 0.0 2.9 3 0 0 3 3 3 1 UBA/TS-N domain CENP-Q PF13094.1 EEQ27593.1 - 0.54 10.2 5.7 0.62 10.0 0.2 2.8 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Synaptobrevin PF00957.16 EEQ27594.1 - 0.39 10.3 3.6 4.2 7.0 0.3 2.1 1 1 1 2 2 2 0 Synaptobrevin Miro PF08477.8 EEQ27595.1 - 2e-37 128.3 0.0 2.6e-19 69.8 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EEQ27595.1 - 2.9e-34 116.6 0.0 5.5e-34 115.7 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EEQ27595.1 - 2e-31 107.0 0.2 3.3e-31 106.3 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EEQ27595.1 - 1.2e-23 83.3 0.0 4.4e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EEQ27595.1 - 7.7e-11 41.9 0.0 5.6e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EEQ27595.1 - 1.6e-08 34.5 0.1 0.0014 18.7 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEQ27595.1 - 1.2e-07 30.9 0.7 0.019 14.8 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EEQ27595.1 - 1.6e-06 27.0 3.9 0.011 14.9 0.1 3.1 3 0 0 3 3 2 2 EF hand AAA_16 PF13191.1 EEQ27595.1 - 2.1e-06 27.8 0.7 0.013 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 EEQ27595.1 - 5e-06 26.4 0.6 0.14 11.9 0.0 3.7 3 1 1 4 4 4 2 Dynamin family AAA_29 PF13555.1 EEQ27595.1 - 6.8e-06 25.5 0.1 0.005 16.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEQ27595.1 - 7.2e-05 22.9 0.0 0.52 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EEQ27595.1 - 0.00028 20.6 0.0 0.22 11.1 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_10 PF14788.1 EEQ27595.1 - 0.00032 20.3 1.6 0.057 13.0 0.1 2.4 2 0 0 2 2 2 1 EF hand AAA_28 PF13521.1 EEQ27595.1 - 0.0013 18.7 0.0 0.6 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.1 EEQ27595.1 - 0.0016 17.6 5.7 0.14 11.5 0.2 3.0 3 0 0 3 3 2 2 EF hand AAA_25 PF13481.1 EEQ27595.1 - 0.0017 17.7 0.1 1.6 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEQ27595.1 - 0.0019 18.1 0.0 0.68 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEQ27595.1 - 0.0021 18.3 0.1 3.8 7.8 0.0 2.9 2 2 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EEQ27595.1 - 0.0023 17.4 0.1 0.077 12.5 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 EEQ27595.1 - 0.003 18.3 0.0 2.1 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EEQ27595.1 - 0.0031 17.8 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 EEQ27595.1 - 0.0037 16.8 0.2 0.19 11.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EEQ27595.1 - 0.0042 16.5 0.0 5.2 6.4 0.0 3.2 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain NACHT PF05729.7 EEQ27595.1 - 0.0055 16.3 0.1 5 6.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EEQ27595.1 - 0.0058 16.7 0.0 0.89 9.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 EEQ27595.1 - 0.007 15.8 0.0 1.1 8.5 0.0 2.5 3 0 0 3 3 2 1 AAA-like domain DUF258 PF03193.11 EEQ27595.1 - 0.011 14.9 0.1 1.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EEQ27595.1 - 0.012 15.1 2.1 4.3 6.7 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EEQ27595.1 - 0.016 14.7 0.2 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family EF-hand_8 PF13833.1 EEQ27595.1 - 0.016 14.8 1.0 4.5 6.9 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair DUF815 PF05673.8 EEQ27595.1 - 0.016 14.1 0.2 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 EEQ27595.1 - 0.016 15.5 0.1 2.8 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EEQ27595.1 - 0.021 13.8 0.0 0.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Septin SMC_N PF02463.14 EEQ27595.1 - 0.022 14.0 0.4 0.65 9.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.9 EEQ27595.1 - 0.057 13.1 0.3 21 4.8 0.0 3.0 2 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EEQ27595.1 - 0.083 12.8 0.1 0.72 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EEQ27595.1 - 0.093 12.9 0.3 9.7 6.4 0.0 2.9 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 EEQ27595.1 - 0.098 11.4 0.6 2.7 6.6 0.0 2.2 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 EEQ27595.1 - 0.11 11.8 1.2 1.9 7.8 0.0 3.1 4 1 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EEQ27595.1 - 0.12 11.4 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin MCM PF00493.18 EEQ27595.1 - 0.13 11.0 0.0 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family IIGP PF05049.8 EEQ27595.1 - 0.28 9.9 0.6 2.2 6.9 0.1 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF500 PF04366.7 EEQ27599.1 - 1.4e-45 153.8 0.2 3.8e-44 149.1 0.2 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EEQ27599.1 - 2.8e-13 49.0 0.1 1.2e-12 46.9 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EEQ27599.1 - 5.6e-13 48.1 0.0 1.3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EEQ27599.1 - 7.4e-13 47.8 0.1 2.3e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Zds_C PF08632.5 EEQ27600.1 - 1.9e-30 103.9 1.7 1.9e-30 103.9 1.2 2.0 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2422 PF10337.4 EEQ27602.1 - 4.4e-40 137.8 0.2 4.4e-40 137.8 0.1 3.1 2 2 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EEQ27602.1 - 5.8e-08 32.6 0.1 4.6e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EEQ27602.1 - 1.3e-05 25.1 8.7 1.3e-05 25.1 6.0 4.0 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 EEQ27602.1 - 2.1 6.8 11.8 0.94 8.0 2.3 3.3 3 1 1 4 4 4 0 Aluminium activated malate transporter DUF939 PF06081.6 EEQ27602.1 - 9.4 6.0 14.3 0.13 12.1 2.4 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF939) WD40 PF00400.27 EEQ27603.1 - 2.2e-20 71.7 14.1 3.1e-06 26.8 0.4 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EEQ27603.1 - 0.00037 20.2 0.0 0.0096 15.6 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EEQ27603.1 - 0.00074 17.4 0.0 0.0013 16.6 0.0 1.4 1 1 0 1 1 1 1 IKI3 family Cytochrom_D1 PF02239.11 EEQ27603.1 - 0.066 11.4 0.0 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Arf PF00025.16 EEQ27604.1 - 1.7e-73 245.5 0.1 2e-73 245.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEQ27604.1 - 7.3e-12 44.9 0.0 8.2e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EEQ27604.1 - 1.3e-11 44.0 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEQ27604.1 - 2.2e-11 43.3 0.0 2.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EEQ27604.1 - 5.3e-11 41.8 1.8 1.7e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EEQ27604.1 - 1.6e-06 28.5 0.0 2.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ27604.1 - 7.4e-05 22.6 0.1 0.00031 20.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EEQ27604.1 - 0.027 13.5 0.3 0.042 12.9 0.0 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Pyr_redox_3 PF13738.1 EEQ27605.1 - 2.8e-20 73.2 0.0 5.7e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ27605.1 - 9.4e-13 47.2 0.0 3.9e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEQ27605.1 - 5.6e-09 35.3 0.0 1.4e-06 27.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEQ27605.1 - 3.2e-07 30.4 0.0 0.00065 19.6 0.0 2.9 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ27605.1 - 4.3e-06 25.9 0.0 5.4e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EEQ27605.1 - 1e-05 25.4 0.6 8.9e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEQ27605.1 - 1.2e-05 25.5 0.6 0.044 14.1 0.2 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEQ27605.1 - 4.2e-05 22.7 0.1 0.055 12.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEQ27605.1 - 0.00012 21.0 0.3 0.013 14.4 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EEQ27605.1 - 0.00018 21.3 0.0 0.085 12.6 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EEQ27605.1 - 0.0013 17.7 0.4 0.059 12.2 0.0 3.1 5 0 0 5 5 5 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ27605.1 - 0.015 14.1 2.7 0.73 8.6 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EEQ27605.1 - 0.02 13.3 2.2 0.063 11.7 0.1 2.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 EEQ27605.1 - 0.024 14.8 0.0 0.88 9.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EEQ27605.1 - 0.091 11.6 2.6 0.36 9.6 0.2 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A F-box-like PF12937.2 EEQ27606.1 - 0.009 15.7 0.2 0.047 13.4 0.1 2.3 1 1 0 1 1 1 1 F-box-like Zn_clus PF00172.13 EEQ27607.1 - 2.2e-10 40.2 9.6 3.3e-10 39.6 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.13 EEQ27608.1 - 1.4e-22 78.6 1.5 1.4e-22 78.6 1.0 2.5 2 1 1 3 3 3 1 Copper fist DNA binding domain Meiotic_rec114 PF03525.9 EEQ27610.1 - 0.00045 18.8 0.0 0.0013 17.3 0.0 1.7 2 0 0 2 2 2 1 Meiotic recombination protein rec114 Mito_carr PF00153.22 EEQ27611.1 - 6.3e-55 182.8 3.8 4.2e-19 68.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.6 EEQ27611.1 - 0.002 17.8 1.3 0.0034 17.0 0.9 1.3 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus DUF3611 PF12263.3 EEQ27611.1 - 0.051 12.9 0.2 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Jun PF03957.8 EEQ27611.1 - 6.3 6.4 7.4 0.72 9.5 1.4 2.1 3 0 0 3 3 3 0 Jun-like transcription factor zf-Nse PF11789.3 EEQ27612.1 - 4.1e-21 74.2 0.6 7.3e-21 73.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EEQ27612.1 - 9.7e-05 22.0 0.4 0.00024 20.7 0.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EEQ27612.1 - 0.00042 20.0 0.2 0.00069 19.4 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain U-box PF04564.10 EEQ27612.1 - 0.0032 17.3 0.1 0.0086 16.0 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-MIZ PF02891.15 EEQ27612.1 - 0.042 13.3 0.8 0.59 9.6 0.1 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 EEQ27612.1 - 0.07 12.8 0.4 0.35 10.5 0.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_I PF01496.14 EEQ27612.1 - 1.8 6.3 7.6 3.7 5.2 5.3 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EEQ27612.1 - 7.2 5.4 15.4 0.045 12.7 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pox_MCEL PF03291.11 EEQ27613.1 - 4.8e-53 180.1 0.0 5.3e-45 153.7 0.0 4.8 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EEQ27613.1 - 4.4e-09 36.7 0.1 6.3e-08 33.0 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27613.1 - 7.9e-08 32.6 0.1 0.018 15.5 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ27613.1 - 3.4e-07 30.8 0.0 8.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ27613.1 - 1.5e-05 24.5 0.0 0.06 12.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ27613.1 - 1.7e-05 24.5 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ27613.1 - 0.0001 22.5 0.0 0.00049 20.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EEQ27613.1 - 0.00012 21.1 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family zf-C3HC PF07967.8 EEQ27614.1 - 8.4e-36 122.6 0.2 1.4e-35 121.9 0.1 1.4 1 0 0 1 1 1 1 C3HC zinc finger-like Rsm1 PF08600.5 EEQ27614.1 - 0.14 12.0 5.1 3.1 7.7 0.0 3.0 3 0 0 3 3 3 0 Rsm1-like MRI PF15325.1 EEQ27614.1 - 0.3 12.0 4.0 3.2 8.7 0.3 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection zf-CHY PF05495.7 EEQ27616.1 - 8.4e-09 35.4 11.3 4.2e-07 30.0 0.5 3.6 3 0 0 3 3 3 2 CHY zinc finger zf-DNA_Pol PF08996.5 EEQ27616.1 - 0.1 11.9 3.1 5.3 6.3 0.2 2.3 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Rep_Org_C PF06926.6 EEQ27616.1 - 0.1 12.7 0.1 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus Polysacc_deac_1 PF01522.16 EEQ27617.1 - 1.9e-20 72.7 0.0 3.2e-19 68.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF3295 PF11702.3 EEQ27619.1 - 3.2e-123 412.4 36.0 3.8e-123 412.1 24.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EEQ27619.1 - 8.2e-12 44.4 2.3 1.7e-11 43.4 1.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cpn60_TCP1 PF00118.19 EEQ27621.1 - 5.4e-147 490.3 3.0 6.2e-147 490.1 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EEQ27621.1 - 0.012 15.5 1.6 3.5 7.5 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Chromo_shadow PF01393.14 EEQ27622.1 - 2.4e-11 43.3 0.0 1.4e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 EEQ27622.1 - 4.4e-11 42.2 0.2 1.8e-10 40.3 0.1 2.1 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Myc_N PF01056.13 EEQ27622.1 - 0.00094 18.4 2.1 0.0016 17.6 1.5 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Rap1_C PF11626.3 EEQ27623.1 - 8.9e-25 86.4 0.1 8.9e-24 83.1 0.1 2.3 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EEQ27623.1 - 5.9e-21 74.0 3.4 1.4e-20 72.8 0.1 2.8 3 0 0 3 3 3 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EEQ27623.1 - 1.1e-09 38.7 0.3 2e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 Rap1, DNA-binding zf-DHHC PF01529.15 EEQ27624.1 - 1.8e-30 105.5 8.9 1.8e-30 105.5 6.2 1.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase LRV_FeS PF05484.6 EEQ27624.1 - 0.28 10.7 4.1 0.51 9.9 2.9 1.4 1 0 0 1 1 1 0 LRV protein FeS4 cluster Atx10homo_assoc PF09759.4 EEQ27625.1 - 1.9e-31 107.8 1.0 6e-31 106.1 0.2 2.2 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain IBR PF01485.16 EEQ27626.1 - 5.1e-07 29.4 22.7 6.1e-07 29.2 4.6 3.5 3 0 0 3 3 3 1 IBR domain zf-RING_UBOX PF13445.1 EEQ27626.1 - 4.9e-05 22.9 2.3 0.0002 20.9 1.6 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EEQ27626.1 - 0.00085 19.1 9.5 0.00085 19.1 6.6 3.4 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ27626.1 - 0.0018 17.9 6.8 0.0018 17.9 4.7 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ27626.1 - 0.0059 16.6 10.3 0.0059 16.6 7.1 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ27626.1 - 0.02 14.6 9.8 0.02 14.6 6.8 3.9 4 1 0 4 4 4 0 zinc-RING finger domain zf-RING_3 PF14369.1 EEQ27626.1 - 0.51 10.3 10.4 0.083 12.8 0.5 3.2 3 0 0 3 3 3 0 zinc-finger zf-RING_2 PF13639.1 EEQ27627.1 - 6.9e-09 35.4 3.6 1.1e-08 34.7 2.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEQ27627.1 - 2e-05 24.6 1.0 4.7e-05 23.4 0.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEQ27627.1 - 0.0014 18.4 0.6 0.0023 17.7 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EEQ27627.1 - 0.0054 16.7 2.4 0.0098 15.9 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EEQ27627.1 - 0.043 13.8 0.2 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 zinc-finger BDHCT PF08072.6 EEQ27627.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 BDHCT (NUC031) domain zf-C3HC4_3 PF13920.1 EEQ27627.1 - 0.14 11.8 1.8 0.87 9.3 1.1 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ27627.1 - 0.2 11.3 1.2 0.39 10.4 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pyridox_oxidase PF01243.15 EEQ27628.1 - 8.2e-09 35.3 0.0 7.1e-05 22.7 0.0 2.9 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EEQ27628.1 - 1.6e-06 28.1 0.0 0.00021 21.3 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Bys1 PF04681.7 EEQ27630.1 - 7.4e-11 41.9 0.1 8.8e-11 41.7 0.1 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NTP_transferase PF00483.18 EEQ27631.1 - 1.2e-28 100.0 0.0 1.5e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EEQ27631.1 - 2.6e-09 36.1 8.7 1.1e-06 27.8 0.1 3.9 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEQ27631.1 - 4.7e-08 33.2 0.0 7.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EEQ27631.1 - 0.0081 15.6 0.0 0.027 13.9 0.0 1.7 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glycos_transf_2 PF00535.21 EEQ27631.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Hexapep_2 PF14602.1 EEQ27631.1 - 0.25 10.9 0.0 0.25 10.9 0.0 3.1 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.18 EEQ27632.1 - 3.6e-25 88.7 0.0 1.8e-24 86.4 0.0 2.2 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ27632.1 - 4.5e-15 55.2 0.0 1e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EEQ27632.1 - 0.00035 20.4 0.0 0.0094 15.8 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ27632.1 - 0.00066 20.1 0.0 0.0038 17.7 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein GED PF02212.13 EEQ27632.1 - 0.00082 19.2 1.2 0.0015 18.3 0.1 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain EBV-NA3 PF05009.7 EEQ27632.1 - 0.092 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Ras PF00071.17 EEQ27632.1 - 0.13 11.6 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 Ras family tRNA-synt_2 PF00152.15 EEQ27633.1 - 5.4e-90 301.5 0.6 7.7e-90 301.0 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ27633.1 - 2.3e-12 46.6 0.1 6e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEQ27633.1 - 3.4e-06 26.4 0.0 0.0066 15.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-RanBP PF00641.13 EEQ27634.1 - 0.012 14.6 3.1 0.012 14.6 2.2 1.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Prok-RING_2 PF14445.1 EEQ27634.1 - 0.026 14.4 4.7 0.049 13.5 3.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-RING_4 PF14570.1 EEQ27634.1 - 0.048 13.2 4.1 0.096 12.2 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 EEQ27634.1 - 0.084 12.6 0.3 0.084 12.6 0.2 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger COX15-CtaA PF02628.10 EEQ27635.1 - 2.5e-94 315.5 8.1 3e-94 315.2 5.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Glyoxalase PF00903.20 EEQ27636.1 - 1e-24 86.9 1.3 6.3e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EEQ27636.1 - 9.9e-15 54.4 0.6 5.1e-07 29.6 0.3 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEQ27636.1 - 1.3e-12 48.2 0.1 1.7e-05 25.4 0.1 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EEQ27636.1 - 1.5e-07 31.4 0.1 0.0013 18.6 0.1 2.9 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EEQ27636.1 - 0.00026 20.9 0.3 0.007 16.2 0.2 2.5 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TPR_11 PF13414.1 EEQ27637.1 - 0.0012 18.4 0.2 0.01 15.4 0.1 2.2 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 EEQ27637.1 - 0.0016 18.5 0.3 0.026 14.7 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ27637.1 - 0.023 15.0 0.4 0.074 13.3 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ27637.1 - 0.12 13.0 1.3 0.17 12.5 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HgmA PF04209.8 EEQ27638.1 - 4.5e-191 634.8 0.0 5.1e-191 634.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 EEQ27639.1 - 3.4e-48 163.9 0.0 4.7e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EEQ27639.1 - 1.1e-24 86.5 0.0 2.2e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_2 PF13409.1 EEQ27640.1 - 2.1e-11 43.6 0.0 4.5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEQ27640.1 - 7.6e-11 42.0 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEQ27640.1 - 3.2e-09 36.8 0.0 5.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ27640.1 - 5.5e-08 32.6 0.1 1.7e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ27640.1 - 0.00052 19.8 0.1 0.0011 18.8 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ27640.1 - 0.001 19.5 0.0 0.0026 18.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF2300 PF10062.4 EEQ27642.1 - 0.079 12.7 0.1 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) Oxidored_FMN PF00724.15 EEQ27643.1 - 1.5e-63 214.8 0.0 2e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family BATS PF06968.8 EEQ27644.1 - 4.1e-28 97.0 0.0 1.3e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EEQ27644.1 - 8.1e-16 58.6 0.0 1.5e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_3 PF00202.16 EEQ27645.1 - 9.3e-43 146.3 0.0 3.5e-23 82.0 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EEQ27645.1 - 1.2e-32 113.1 0.0 2.1e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.16 EEQ27646.1 - 3.2e-38 131.6 0.0 4e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ27646.1 - 0.0052 15.5 0.0 1.5 7.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EEQ27646.1 - 0.094 10.9 0.0 0.14 10.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GTP_EFTU PF00009.22 EEQ27647.1 - 3.5e-42 143.9 0.0 5.3e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEQ27647.1 - 2.7e-20 72.3 0.1 5.5e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEQ27647.1 - 1e-08 35.1 0.1 2.6e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ27647.1 - 0.0018 18.2 0.0 0.0044 16.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EEQ27647.1 - 0.052 12.2 1.0 0.13 10.8 0.7 1.7 1 1 0 1 1 1 0 G-protein alpha subunit Med15 PF09606.5 EEQ27647.1 - 6.4 4.8 47.8 9.9 4.2 33.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CTP_transf_2 PF01467.21 EEQ27648.1 - 1.1e-25 90.5 0.0 1.5e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Ran-binding PF05508.6 EEQ27649.1 - 2.6e-88 295.8 4.2 1.1e-38 132.8 2.0 3.1 1 1 2 3 3 3 3 RanGTP-binding protein UCH PF00443.24 EEQ27650.1 - 6.8e-40 136.8 0.4 1.1e-39 136.2 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EEQ27650.1 - 3.7e-37 127.8 0.0 6.5e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 EEQ27650.1 - 4e-15 56.0 0.0 6.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EEQ27650.1 - 1.2e-06 28.7 0.0 2.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 MATH domain BSD PF03909.12 EEQ27651.1 - 4.4e-16 58.3 0.2 1.2e-15 56.9 0.2 1.8 1 0 0 1 1 1 1 BSD domain Rad4 PF03835.10 EEQ27653.1 - 1.8e-34 118.2 0.0 3.9e-34 117.1 0.0 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EEQ27653.1 - 2.9e-27 94.1 0.0 7.3e-27 92.8 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EEQ27653.1 - 3.1e-20 71.4 0.0 6.3e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EEQ27653.1 - 1.1e-14 54.4 0.1 3.1e-14 53.0 0.1 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Filament PF00038.16 EEQ27654.1 - 9.3e-05 22.0 163.8 0.0059 16.1 36.3 6.5 2 1 4 6 6 6 4 Intermediate filament protein AAA_13 PF13166.1 EEQ27654.1 - 0.00013 20.6 34.4 0.00013 20.6 23.8 5.9 1 1 5 6 6 6 2 AAA domain DUF3584 PF12128.3 EEQ27654.1 - 0.00053 17.4 36.3 0.00053 17.4 25.2 4.8 1 1 2 4 4 4 2 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.2 EEQ27654.1 - 0.0011 18.8 43.6 0.0016 18.2 13.9 9.3 2 1 5 9 9 9 4 Tropomyosin like CENP-F_leu_zip PF10473.4 EEQ27654.1 - 0.0027 17.5 22.7 0.0027 17.5 15.7 10.2 2 1 7 10 10 10 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1202 PF06717.6 EEQ27654.1 - 0.0044 16.3 11.2 0.0044 16.3 7.8 6.2 2 2 3 6 6 6 1 Protein of unknown function (DUF1202) Myb_DNA-binding PF00249.26 EEQ27655.1 - 0.007 16.3 0.1 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain PTPA PF03095.10 EEQ27656.1 - 4.6e-101 337.9 0.0 5.4e-101 337.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ribosomal_S7 PF00177.16 EEQ27656.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e Glyco_hydro_3 PF00933.16 EEQ27657.1 - 5.9e-65 219.1 0.0 2.6e-48 164.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEQ27657.1 - 1.5e-52 178.4 0.0 4.1e-52 176.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain DUF572 PF04502.8 EEQ27657.1 - 2e-49 168.5 0.1 3e-49 168.0 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Fn3-like PF14310.1 EEQ27657.1 - 1.1e-15 57.3 0.0 2.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PNP_UDP_1 PF01048.15 EEQ27658.1 - 6.7e-37 126.6 0.0 8.3e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2757 PF10955.3 EEQ27658.1 - 0.028 14.6 0.1 0.066 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) BUD22 PF09073.5 EEQ27659.1 - 1.2e-90 304.6 20.0 1.7e-90 304.2 13.9 1.2 1 0 0 1 1 1 1 BUD22 SIS PF01380.17 EEQ27660.1 - 7.7e-13 48.1 0.0 1.9e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EEQ27660.1 - 1.7e-05 24.5 0.0 3.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 SIS domain Ubie_methyltran PF01209.13 EEQ27662.1 - 3e-78 262.1 0.0 7.6e-78 260.8 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EEQ27662.1 - 3e-14 52.8 0.0 3.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27662.1 - 5.2e-13 49.3 0.0 1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ27662.1 - 6.8e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ27662.1 - 1.2e-09 38.0 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ27662.1 - 2.8e-09 37.2 0.0 6.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ27662.1 - 7.5e-09 36.1 0.0 1.3e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ27662.1 - 2.1e-05 24.5 0.0 4.5e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EEQ27662.1 - 0.027 14.0 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Sororin PF09666.5 EEQ27662.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Sororin protein Methyltransf_24 PF13578.1 EEQ27662.1 - 0.13 13.1 0.0 0.25 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain E1_dh PF00676.15 EEQ27663.1 - 3.4e-90 301.8 0.1 4.1e-90 301.5 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EEQ27663.1 - 0.00084 18.9 0.1 0.0025 17.3 0.1 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EEQ27663.1 - 0.012 14.5 0.0 0.023 13.6 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 EEQ27663.1 - 0.044 12.3 0.0 0.14 10.6 0.0 1.7 2 0 0 2 2 2 0 XFP N-terminal domain zf-RING_4 PF14570.1 EEQ27664.1 - 5.5e-19 67.4 13.4 1.1e-18 66.5 9.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EEQ27664.1 - 5.4e-05 22.7 7.2 9.2e-05 22.0 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EEQ27664.1 - 0.0002 20.9 0.0 0.00046 19.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 EEQ27664.1 - 0.0017 18.0 5.0 0.0035 17.0 3.5 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 EEQ27664.1 - 0.0033 17.2 0.0 0.0087 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EEQ27664.1 - 0.19 11.4 12.7 0.37 10.4 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ27664.1 - 1.2 9.2 11.9 2.3 8.2 8.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.14 EEQ27665.1 - 8.9e-36 122.2 0.1 1.5e-35 121.5 0.1 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Myb_DNA-binding PF00249.26 EEQ27667.1 - 0.00024 21.0 2.1 0.00042 20.3 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ27667.1 - 0.0038 17.2 2.3 0.018 15.1 0.4 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain TSGP1 PF07771.6 EEQ27667.1 - 0.043 13.7 0.5 0.09 12.6 0.4 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 Rz1 PF06085.6 EEQ27668.1 - 0.66 9.4 5.9 0.081 12.3 0.8 2.0 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor AA_permease_2 PF13520.1 EEQ27669.1 - 1.4e-92 310.4 32.2 1.7e-92 310.1 22.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ27669.1 - 3.4e-19 68.5 28.5 5.9e-19 67.7 19.8 1.4 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 EEQ27670.1 - 6.5e-44 150.2 0.0 3.9e-33 114.6 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 BolA PF01722.13 EEQ27670.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 BolA-like protein FMO-like PF00743.14 EEQ27671.1 - 2.4e-90 303.2 0.0 3.1e-89 299.5 0.0 1.9 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEQ27671.1 - 2.2e-23 83.3 0.0 4e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ27671.1 - 4.1e-10 39.0 0.0 2.1e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEQ27671.1 - 2.1e-07 30.8 0.1 0.00019 21.2 0.0 3.0 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEQ27671.1 - 5.4e-07 29.5 0.0 1.5e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEQ27671.1 - 0.00015 22.0 0.8 0.12 12.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ27671.1 - 0.00054 19.8 0.0 0.0025 17.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ27671.1 - 0.003 16.5 0.4 0.013 14.3 0.1 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EEQ27671.1 - 0.2 11.7 0.4 10 6.2 0.1 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_3 PF07859.8 EEQ27672.1 - 1.2e-61 207.9 0.4 1.8e-61 207.4 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ27672.1 - 1.1e-06 28.0 0.0 0.00074 18.7 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 EEQ27672.1 - 0.0001 21.2 0.7 0.00029 19.7 0.5 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EEQ27672.1 - 0.028 14.1 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.4 EEQ27672.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Lyase_1 PF00206.15 EEQ27673.1 - 6.3e-112 373.8 0.0 8.6e-112 373.3 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EEQ27673.1 - 1.3e-22 79.5 0.0 3.7e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 EEQ27673.1 - 0.11 12.2 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Acetyltransf_7 PF13508.1 EEQ27675.1 - 3.9e-11 42.9 0.1 5.9e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ27675.1 - 4.3e-10 39.4 0.1 9.7e-10 38.3 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EEQ27675.1 - 0.0025 17.6 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Thiolase_C PF02803.13 EEQ27675.1 - 0.061 12.7 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Thiolase, C-terminal domain Acetyltransf_10 PF13673.1 EEQ27675.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L24e PF01246.15 EEQ27676.1 - 3.9e-31 106.7 0.3 3.9e-31 106.7 0.2 2.0 2 1 0 2 2 2 1 Ribosomal protein L24e UQ_con PF00179.21 EEQ27677.1 - 3.7e-47 159.2 0.0 4.1e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ27677.1 - 0.00022 21.0 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ27677.1 - 0.0084 16.0 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EEQ27677.1 - 0.0093 15.6 0.1 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 UEV domain WD40 PF00400.27 EEQ27678.1 - 1.2e-13 50.3 14.6 5.5e-05 22.8 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 EEQ27678.1 - 0.049 13.6 11.2 0.13 12.3 7.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ27678.1 - 0.13 12.1 10.2 0.41 10.5 7.1 1.9 1 0 0 1 1 1 0 Ring finger domain RdgC PF04381.7 EEQ27678.1 - 0.31 9.9 0.4 0.57 9.0 0.3 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC SseB_C PF14581.1 EEQ27679.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 SseB protein C-terminal domain 4HBT PF03061.17 EEQ27680.1 - 4.5e-09 36.2 0.0 8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EEQ27680.1 - 0.00082 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) UCH PF00443.24 EEQ27681.1 - 5.4e-54 183.1 0.8 6.8e-54 182.7 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ27681.1 - 1.6e-15 57.3 7.4 8.2e-15 55.0 5.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EEQ27681.1 - 1.6e-11 43.4 0.0 4.1e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family IMD PF08397.6 EEQ27681.1 - 0.022 14.0 0.1 0.022 14.0 0.0 2.5 3 0 0 3 3 3 0 IRSp53/MIM homology domain Ubiquitin_2 PF14560.1 EEQ27681.1 - 0.039 14.2 0.1 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain ARPC4 PF05856.7 EEQ27682.1 - 5.2e-75 250.5 3.4 5.8e-75 250.3 2.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_6 PF14259.1 EEQ27683.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 EEQ27683.1 - 9.1 4.0 7.7 15 3.3 5.4 1.3 1 0 0 1 1 1 0 Nop14-like family TYW3 PF02676.9 EEQ27684.1 - 6.7e-65 218.0 0.0 8.4e-65 217.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2461 PF09365.5 EEQ27685.1 - 4e-61 206.1 0.2 7.3e-61 205.2 0.2 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) DUF2763 PF10961.3 EEQ27687.1 - 1.2 9.5 5.4 1.3 9.4 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Zn_clus PF00172.13 EEQ27688.1 - 7.5e-09 35.3 7.3 1.1e-08 34.8 5.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EEQ27689.1 - 5.9e-69 232.1 0.0 1.1e-68 231.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27689.1 - 1.7e-30 105.9 0.0 7e-29 100.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ27689.1 - 0.00086 18.3 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ27689.1 - 0.0088 15.1 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ27689.1 - 0.036 13.8 0.6 0.15 11.7 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF1690 PF07956.6 EEQ27690.1 - 9.1e-30 103.4 2.3 4.9e-14 52.5 0.3 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.1 EEQ27690.1 - 0.014 15.3 3.6 0.14 12.1 0.2 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Phasin PF05597.6 EEQ27690.1 - 0.19 11.5 2.1 0.26 11.0 0.2 2.0 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) POP1 PF06978.6 EEQ27691.1 - 1.4e-63 213.9 14.5 1.4e-63 213.9 10.0 2.4 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EEQ27691.1 - 2.5e-30 104.1 2.4 2.5e-30 104.1 1.6 2.4 2 0 0 2 2 2 1 POPLD (NUC188) domain Maf PF02545.9 EEQ27691.1 - 0.074 12.1 0.0 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Maf-like protein Redoxin PF08534.5 EEQ27692.1 - 1.9e-38 131.2 0.1 2.1e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EEQ27692.1 - 7.2e-15 54.7 0.0 8.8e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Hexokinase_2 PF03727.11 EEQ27693.1 - 6.1e-66 222.0 0.0 8.3e-66 221.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EEQ27693.1 - 1.5e-63 213.8 0.0 3e-63 212.8 0.0 1.5 1 1 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 EEQ27693.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain zf-C2HC5 PF06221.8 EEQ27694.1 - 4.7e-20 71.0 5.5 7.5e-20 70.4 3.8 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Phospholip_A2_3 PF09056.6 EEQ27695.1 - 1.8e-38 131.1 4.7 2.2e-38 130.9 3.3 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 DUF604 PF04646.7 EEQ27696.1 - 5.1e-07 29.1 0.0 8.1e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EEQ27696.1 - 0.001 18.3 0.0 0.0024 17.1 0.0 1.5 1 1 0 1 1 1 1 Fringe-like GDI PF00996.13 EEQ27697.1 - 4.4e-40 137.3 0.0 5.9e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor DAO PF01266.19 EEQ27697.1 - 0.051 12.4 0.0 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pro_isomerase PF00160.16 EEQ27698.1 - 4.6e-44 150.3 0.0 5.5e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.8 EEQ27699.1 - 1.4e-53 182.3 0.0 4e-53 180.8 0.0 1.7 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EEQ27699.1 - 0.00076 18.6 6.6 0.00076 18.6 4.5 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) DUF4231 PF14015.1 EEQ27699.1 - 0.57 10.1 1.9 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2955 PF11168.3 EEQ27699.1 - 0.72 9.5 13.3 0.94 9.1 4.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2955) RNase_PH PF01138.16 EEQ27700.1 - 1.1e-17 64.5 1.3 4.4e-16 59.4 0.9 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_binding_6 PF08030.7 EEQ27701.1 - 6.8e-21 74.7 0.0 3.1e-20 72.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ27701.1 - 2.3e-16 59.5 0.0 6.5e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EEQ27701.1 - 7.3e-16 58.3 8.7 7.3e-16 58.3 6.0 1.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EEQ27701.1 - 0.0021 18.5 0.0 3.4 8.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EEQ27701.1 - 0.18 11.9 9.0 0.17 12.0 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Acetyltransf_1 PF00583.19 EEQ27702.1 - 2.3e-06 27.5 0.0 0.0039 17.2 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Sgf11 PF08209.6 EEQ27703.1 - 2.6e-07 29.8 1.6 1.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) YjgP_YjgQ PF03739.9 EEQ27704.1 - 0.081 11.6 1.5 0.14 10.8 1.1 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family PGPGW PF09656.5 EEQ27704.1 - 1.8 7.9 6.5 0.39 10.0 0.3 2.3 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) SRF-TF PF00319.13 EEQ27705.1 - 1.4e-23 81.8 0.2 2e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Fungal_trans_2 PF11951.3 EEQ27706.1 - 8.6e-06 24.5 0.5 1.1e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain CDC37_M PF08565.6 EEQ27706.1 - 0.21 11.0 0.2 0.8 9.1 0.1 1.8 2 0 0 2 2 2 0 Cdc37 Hsp90 binding domain Lactonase PF10282.4 EEQ27707.1 - 7.6e-85 285.0 0.0 9.3e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 EEQ27707.1 - 0.063 13.1 0.0 0.3 11.0 0.0 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat Mg_trans_NIPA PF05653.9 EEQ27708.1 - 3.4e-14 52.4 9.0 1e-08 34.4 0.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EEQ27708.1 - 1.8e-06 27.9 13.0 8.8e-06 25.7 0.6 2.8 2 0 0 2 2 2 2 EamA-like transporter family TMEM61 PF15105.1 EEQ27708.1 - 0.01 15.3 0.1 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 TMEM61 protein family Multi_Drug_Res PF00893.14 EEQ27708.1 - 0.026 14.9 5.2 0.1 13.0 0.1 2.7 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF2306 PF10067.4 EEQ27708.1 - 0.8 9.8 9.3 52 4.0 1.0 3.7 4 0 0 4 4 4 0 Predicted membrane protein (DUF2306) vATP-synt_E PF01991.13 EEQ27709.1 - 1.4e-57 194.1 11.6 1.6e-57 193.9 8.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.1 EEQ27709.1 - 0.038 14.1 5.0 22 5.2 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) Scaffolding_pro PF11418.3 EEQ27709.1 - 0.55 10.5 5.4 0.18 12.1 1.2 2.0 2 0 0 2 2 2 0 Phi29 scaffolding protein E1-E2_ATPase PF00122.15 EEQ27712.1 - 2.6e-12 46.2 0.0 5.9e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EEQ27712.1 - 4.1e-12 45.9 0.0 1.1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ27712.1 - 9.2e-12 45.5 0.1 2.4e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ27712.1 - 1.1e-10 42.3 3.1 3.1e-07 31.0 1.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ27712.1 - 0.028 13.9 0.2 0.069 12.7 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1828 PF08861.5 EEQ27712.1 - 0.11 12.1 0.2 0.62 9.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF1828 SEN1_N PF12726.2 EEQ27713.1 - 2.2e-103 346.7 0.1 2.6e-103 346.4 0.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EEQ27714.1 - 3e-68 229.9 1.9 3e-68 229.9 1.3 2.2 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EEQ27714.1 - 6.1e-60 202.0 0.0 1.1e-59 201.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.2 EEQ27714.1 - 1.2e-50 172.3 2.7 1.7e-50 171.8 1.9 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.1 EEQ27714.1 - 2.3e-11 43.2 0.0 7e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ27714.1 - 6.4e-09 35.6 0.0 8.1e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EEQ27714.1 - 4.1e-08 33.0 0.0 0.0077 15.7 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EEQ27714.1 - 1.2e-07 31.3 0.1 1.7e-05 24.3 0.1 2.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain zf-CCHC PF00098.18 EEQ27714.1 - 3.7e-05 23.4 9.8 0.00062 19.5 0.3 3.1 3 0 0 3 3 3 2 Zinc knuckle ResIII PF04851.10 EEQ27714.1 - 0.0061 16.3 0.0 0.03 14.1 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EEQ27714.1 - 0.013 14.3 0.0 0.051 12.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.1 EEQ27714.1 - 0.044 13.1 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2464 PF10240.4 EEQ27714.1 - 0.08 12.2 3.3 0.036 13.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2464) AAA_23 PF13476.1 EEQ27714.1 - 0.089 13.1 3.8 0.036 14.3 0.3 2.0 2 0 0 2 2 2 0 AAA domain zf-CCHC_5 PF14787.1 EEQ27714.1 - 0.38 10.2 6.2 3.9 7.0 2.5 2.7 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger CAP59_mtransfer PF11735.3 EEQ27716.1 - 1.2e-67 227.6 0.0 1.7e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CorA PF01544.13 EEQ27718.1 - 1.1e-08 34.4 0.0 1.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0104 PF03706.8 EEQ27718.1 - 0.11 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Pkinase PF00069.20 EEQ27719.1 - 1.2e-20 73.7 0.0 2.6e-20 72.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27719.1 - 1.9e-06 27.1 0.0 0.00024 20.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEQ27719.1 - 0.11 12.1 0.2 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family WH1 PF00568.18 EEQ27720.1 - 1e-28 99.2 0.0 1.5e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EEQ27720.1 - 0.0058 16.1 0.1 0.016 14.7 0.1 1.8 1 0 0 1 1 1 1 WH2 motif eIF-1a PF01176.14 EEQ27722.1 - 1.3e-28 98.2 0.1 1.8e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.10 EEQ27723.1 - 1.8e-24 86.1 0.0 2.6e-23 82.3 0.0 2.7 3 0 0 3 3 3 1 ERCC4 domain PTCB-BRCT PF12738.2 EEQ27724.1 - 9.7e-13 47.7 0.0 1.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EEQ27724.1 - 4.8e-07 29.8 0.0 8.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 EEQ27724.1 - 0.00083 19.0 0.0 0.0025 17.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 EEQ27724.1 - 0.0017 18.4 0.0 0.0044 17.1 0.0 1.7 1 1 0 1 1 1 1 Fibronectin type III domain Peptidase_S10 PF00450.17 EEQ27725.1 - 1.2e-84 284.9 0.0 1.6e-84 284.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_1 PF00583.19 EEQ27726.1 - 0.00032 20.6 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ27726.1 - 0.00052 20.1 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ27726.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ27726.1 - 0.0041 17.2 0.0 0.0075 16.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ27726.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SRPRB PF09439.5 EEQ27726.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Acetyltransf_7 PF13508.1 EEQ27727.1 - 1.4e-06 28.3 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ27727.1 - 9.2e-06 25.6 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEQ27727.1 - 0.00018 21.5 0.0 0.0019 18.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ27727.1 - 0.00067 19.5 0.0 0.0088 15.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ27727.1 - 0.14 11.8 0.0 0.84 9.4 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Porphobil_deam PF01379.15 EEQ27728.1 - 1.6e-75 252.7 0.0 2.3e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EEQ27728.1 - 2e-19 69.4 0.1 3.9e-19 68.5 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GFA PF04828.9 EEQ27729.1 - 1.7e-10 40.6 2.4 2.3e-05 24.2 0.1 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 EEQ27729.1 - 0.012 15.4 1.1 0.033 14.0 0.7 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 EEQ27729.1 - 0.038 13.4 0.6 0.17 11.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 EEQ27729.1 - 10 5.7 8.2 1.4 8.5 0.7 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain MFS_1 PF07690.11 EEQ27730.1 - 1e-44 152.7 37.5 1e-44 152.7 26.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ27730.1 - 6e-10 38.2 9.9 6e-10 38.2 6.9 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ27731.1 - 4.8e-18 65.0 50.2 5.7e-16 58.1 20.6 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Bromo_coat PF01318.13 EEQ27731.1 - 0.045 13.4 0.2 0.083 12.5 0.2 1.3 1 0 0 1 1 1 0 Bromovirus coat protein Evr1_Alr PF04777.8 EEQ27732.1 - 6.4e-26 90.1 0.0 9.7e-26 89.5 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family R3H PF01424.17 EEQ27734.1 - 5e-12 45.3 0.0 4.7e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.12 EEQ27734.1 - 7.3e-05 22.6 57.7 0.00098 19.0 9.1 13.8 12 2 2 14 14 14 7 NF-X1 type zinc finger Pkinase PF00069.20 EEQ27735.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain ARID PF01388.16 EEQ27737.1 - 1.3e-17 63.4 1.0 2.4e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Neur_chan_memb PF02932.11 EEQ27737.1 - 1.8 8.3 10.3 4.3 7.1 7.2 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Img2 PF05046.9 EEQ27738.1 - 1e-27 96.1 0.0 1.6e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.5 EEQ27739.1 - 1.4e-47 161.1 2.8 3.3e-47 159.9 1.9 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EEQ27739.1 - 9.1e-14 51.6 0.2 3e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 PCI domain DUF2564 PF10819.3 EEQ27739.1 - 0.0045 17.0 0.1 2.7 8.1 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2564) PCI_Csn8 PF10075.4 EEQ27739.1 - 0.0061 16.3 0.1 0.021 14.5 0.0 1.9 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 HD_3 PF13023.1 EEQ27739.1 - 0.042 13.5 0.8 0.089 12.5 0.6 1.5 1 0 0 1 1 1 0 HD domain DUF445 PF04286.7 EEQ27739.1 - 2 7.8 6.3 0.36 10.3 1.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF445) ArsA_ATPase PF02374.10 EEQ27742.1 - 3.8e-113 377.5 0.0 4.4e-113 377.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EEQ27742.1 - 1.5e-16 60.3 0.1 2.4e-16 59.7 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEQ27742.1 - 4.7e-08 33.1 0.0 1.9e-05 24.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain Fer4_NifH PF00142.13 EEQ27742.1 - 5.8e-06 25.6 0.1 1.3e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EEQ27742.1 - 2.1e-05 24.0 0.3 0.00051 19.5 0.0 2.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MipZ PF09140.6 EEQ27742.1 - 0.016 14.3 0.1 0.054 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ YhjQ PF06564.7 EEQ27742.1 - 0.025 13.9 0.0 0.063 12.6 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein NB-ARC PF00931.17 EEQ27742.1 - 0.034 13.0 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 EEQ27742.1 - 0.038 13.3 0.2 0.1 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EEQ27742.1 - 0.041 13.0 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.12 EEQ27742.1 - 0.068 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EEQ27742.1 - 0.099 12.4 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain Ferric_reduct PF01794.14 EEQ27743.1 - 1e-17 64.3 14.0 1e-17 64.3 9.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EEQ27743.1 - 4.1e-15 56.0 0.0 8.1e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ27743.1 - 2.2e-07 30.6 0.0 0.0076 16.1 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EEQ27743.1 - 0.022 15.3 0.0 4.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Transthyretin PF00576.16 EEQ27744.1 - 2.9e-19 68.9 0.0 3.7e-11 42.9 0.0 2.6 2 1 0 2 2 2 2 HIUase/Transthyretin family Aft1_HRA PF11786.3 EEQ27745.1 - 4e-26 91.0 12.0 4e-26 91.0 8.4 3.9 4 0 0 4 4 4 1 Aft1 HRA domain Aft1_HRR PF11787.3 EEQ27745.1 - 4.9e-18 65.9 4.3 4.9e-18 65.9 3.0 4.0 4 0 0 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.3 EEQ27745.1 - 5.2e-12 46.0 5.3 5.2e-12 46.0 3.7 3.1 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EEQ27745.1 - 1e-08 35.0 9.2 1.7e-08 34.2 6.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ27745.1 - 0.00036 20.2 7.6 0.00063 19.5 5.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEQ27745.1 - 0.031 14.5 3.0 0.06 13.6 2.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor HeLo PF14479.1 EEQ27745.1 - 0.076 12.7 1.1 0.13 11.9 0.7 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation PARP PF00644.15 EEQ27746.1 - 3.5e-11 42.9 0.1 6.9e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EEQ27746.1 - 2e-07 30.5 0.0 4.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEQ27746.1 - 0.089 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 RWD domain COG7 PF10191.4 EEQ27747.1 - 0.0068 14.3 0.0 0.026 12.4 0.0 1.8 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) RNA_pol_Rpb4 PF03874.11 EEQ27748.1 - 1.1e-07 31.8 0.6 0.0034 17.3 0.0 2.5 2 1 0 2 2 2 2 RNA polymerase Rpb4 GST_N PF02798.15 EEQ27749.1 - 2.4e-19 69.2 0.0 2.1e-18 66.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEQ27749.1 - 1.9e-16 60.0 0.0 3.5e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ27749.1 - 6.9e-16 58.0 0.0 1.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ27749.1 - 2.1e-12 46.8 0.4 3.7e-12 46.0 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ27749.1 - 7.6e-09 35.3 1.2 1.3e-08 34.5 0.8 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ27749.1 - 1e-07 32.3 0.1 1.4e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Nop PF01798.13 EEQ27750.1 - 3.6e-55 185.3 0.6 9.7e-55 183.9 0.4 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOP5NT PF08156.8 EEQ27750.1 - 6.7e-22 77.4 1.3 6.7e-22 77.4 0.9 2.7 3 0 0 3 3 3 1 NOP5NT (NUC127) domain NOSIC PF08060.8 EEQ27750.1 - 6e-10 38.7 1.0 4.7e-08 32.7 0.7 2.4 1 1 0 1 1 1 1 NOSIC (NUC001) domain vATP-synt_AC39 PF01992.11 EEQ27751.1 - 5.1e-109 364.4 0.0 5.7e-109 364.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.1 EEQ27752.1 - 1.4e-41 142.2 1.8 8.8e-36 123.3 0.5 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EEQ27752.1 - 9.7e-33 112.3 0.0 3.1e-32 110.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EEQ27752.1 - 9.8e-12 44.6 0.2 2.6e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEQ27752.1 - 0.00067 18.9 0.1 0.0012 18.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SbcCD_C PF13558.1 EEQ27753.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ubiquitin PF00240.18 EEQ27754.1 - 0.00052 19.3 0.0 0.00084 18.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EEQ27754.1 - 0.054 14.0 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PIG-H PF10181.4 EEQ27755.1 - 1.6e-26 91.7 0.1 1.6e-26 91.7 0.0 1.9 3 0 0 3 3 3 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.15 EEQ27756.1 - 3.9e-30 104.3 0.0 1.1e-22 80.4 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase Striatin PF08232.7 EEQ27756.1 - 0.53 10.6 7.3 1 9.7 5.1 1.3 1 0 0 1 1 1 0 Striatin family Amidoligase_2 PF12224.3 EEQ27757.1 - 2e-09 37.4 0.0 3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Ribosomal_S2 PF00318.15 EEQ27758.1 - 1.5e-42 145.1 0.0 1.6e-21 76.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 EEQ27759.1 - 3.6e-15 55.4 1.7 5e-15 55.0 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 DEAD PF00270.24 EEQ27761.1 - 8.3e-34 116.5 0.0 1.3e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEQ27761.1 - 8.2e-20 70.1 0.0 1.6e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EEQ27761.1 - 5.3e-18 64.6 0.0 1.1e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ27761.1 - 0.08 12.7 0.0 0.25 11.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RC-P840_PscD PF10657.4 EEQ27761.1 - 0.11 12.3 0.3 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD SRP_SPB PF02978.14 EEQ27761.1 - 0.16 12.2 4.7 0.37 11.0 2.8 1.9 2 0 0 2 2 2 0 Signal peptide binding domain CTP_transf_1 PF01148.15 EEQ27762.1 - 2.3e-15 56.9 6.6 3.2e-15 56.4 4.6 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family XPG_I PF00867.13 EEQ27763.1 - 9.9e-22 76.8 0.1 2.2e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EEQ27763.1 - 3.3e-06 27.2 0.0 8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 EEQ27764.1 - 2.5e-23 82.1 0.0 1.3e-19 69.8 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EEQ27764.1 - 0.072 11.6 0.0 0.19 10.2 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein Aldose_epim PF01263.15 EEQ27766.1 - 7.4e-51 173.0 0.3 9.4e-51 172.6 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.20 EEQ27768.1 - 4.4e-11 42.4 0.0 7e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27768.1 - 3e-09 36.3 0.0 4.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Trypsin_2 PF13365.1 EEQ27769.1 - 0.0064 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Carb_anhydrase PF00194.16 EEQ27770.1 - 0.022 13.7 0.0 0.048 12.6 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic-type carbonic anhydrase HECT PF00632.20 EEQ27770.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) APH PF01636.18 EEQ27771.1 - 4.3e-06 26.6 0.6 7.7e-06 25.8 0.3 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ27771.1 - 0.0041 16.7 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4130 PF13566.1 EEQ27771.1 - 0.029 13.9 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 Sec34 PF04136.10 EEQ27772.1 - 3.9e-29 101.3 1.3 7.7e-29 100.4 0.2 2.0 2 0 0 2 2 2 1 Sec34-like family SYCE1 PF15233.1 EEQ27772.1 - 0.0039 17.1 0.1 0.021 14.7 0.1 2.2 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 CR6_interact PF10147.4 EEQ27773.1 - 0.0031 16.8 2.3 0.0031 16.8 1.6 2.2 3 0 0 3 3 3 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Neur_chan_memb PF02932.11 EEQ27773.1 - 0.13 12.1 1.4 0.17 11.7 0.1 1.8 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Mannitol_dh_C PF08125.8 EEQ27774.1 - 8.3e-45 152.8 0.0 1.4e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EEQ27774.1 - 1.5e-19 70.4 0.4 4e-19 69.0 0.1 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain NAD_Gly3P_dh_N PF01210.18 EEQ27774.1 - 0.0068 16.1 0.1 0.017 14.8 0.0 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EEQ27774.1 - 0.044 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EEQ27774.1 - 0.045 13.1 0.2 0.086 12.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_synt_2 PF02719.10 EEQ27774.1 - 0.07 12.0 0.5 0.45 9.3 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pyr_redox PF00070.22 EEQ27774.1 - 0.099 13.0 0.4 0.52 10.7 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RCC1 PF00415.13 EEQ27775.1 - 3.1e-33 113.7 5.0 2.4e-08 34.0 0.1 6.6 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEQ27775.1 - 7.5e-18 63.6 20.8 8.8e-07 28.3 0.1 6.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.1 EEQ27775.1 - 1.8 8.3 6.9 31 4.4 0.1 4.3 4 0 0 4 4 4 0 Galactose oxidase, central domain Rad9 PF04139.8 EEQ27776.1 - 9.5e-61 205.0 0.1 1.2e-60 204.7 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EEQ27776.1 - 6e-06 25.2 0.0 4.7e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Pkinase PF00069.20 EEQ27777.1 - 9.3e-64 215.0 0.0 1.4e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27777.1 - 1.3e-43 148.9 0.0 2e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ27777.1 - 1.7e-09 37.1 0.0 1e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EEQ27777.1 - 0.0031 16.5 0.0 0.006 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RepL PF05732.6 EEQ27777.1 - 0.05 12.8 0.1 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Spc97_Spc98 PF04130.8 EEQ27780.1 - 7.5e-118 394.1 0.0 1.1e-117 393.6 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family FSA_C PF10479.4 EEQ27780.1 - 0.18 9.8 0.0 0.27 9.2 0.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2373 PF10180.4 EEQ27781.1 - 1.5e-20 72.4 0.0 2.9e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 EEQ27782.1 - 4.7e-49 166.2 0.0 6.2e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEQ27782.1 - 5e-13 48.1 0.3 9.5e-13 47.2 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.12 EEQ27782.1 - 0.005 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family DUF3619 PF12279.3 EEQ27784.1 - 0.059 13.4 0.6 0.096 12.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) PTR2 PF00854.16 EEQ27787.1 - 3.5e-49 167.5 18.5 4.5e-47 160.6 12.8 2.3 1 1 0 1 1 1 1 POT family Glyco_hydro_18 PF00704.23 EEQ27788.1 - 1.1e-100 337.5 4.4 1.2e-100 337.2 3.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 EEQ27789.1 - 1.7e-34 117.0 1.1 2.8e-34 116.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EEQ27789.1 - 7.5e-28 96.1 1.9 1.6e-27 95.0 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EEQ27789.1 - 7.9e-20 70.3 0.8 1.4e-19 69.5 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEQ27789.1 - 9.6e-06 25.7 0.2 4.3e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEQ27789.1 - 0.00016 21.4 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEQ27789.1 - 0.00077 19.3 0.5 0.0017 18.2 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEQ27789.1 - 0.0035 17.4 0.5 0.0048 17.0 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EEQ27789.1 - 0.0091 15.8 0.5 0.015 15.1 0.4 1.3 1 0 0 1 1 1 1 IBR domain DUF2207 PF09972.4 EEQ27789.1 - 0.038 12.5 0.3 0.041 12.4 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2870 PF11069.3 EEQ27789.1 - 0.064 13.2 0.2 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EEQ27789.1 - 0.13 10.5 2.3 2.3 6.4 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain zf-H2C2_2 PF13465.1 EEQ27790.1 - 2.3e-10 40.2 10.9 1.9e-05 24.6 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ27790.1 - 1.3e-06 28.4 19.0 0.0036 17.5 3.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ27790.1 - 0.00011 22.2 13.4 0.067 13.5 1.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ27790.1 - 0.013 15.4 8.3 0.24 11.3 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EEQ27790.1 - 0.26 11.0 7.3 0.24 11.1 3.6 2.1 1 1 1 2 2 2 0 BED zinc finger DUF155 PF02582.9 EEQ27791.1 - 3.1e-44 150.9 0.0 5.8e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.15 EEQ27792.1 - 2.9e-18 65.8 0.1 8.9e-18 64.2 0.0 1.8 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EEQ27792.1 - 1.7e-07 30.8 2.9 0.039 13.8 0.3 4.3 4 1 0 4 4 4 2 WD domain, G-beta repeat zf-RING_5 PF14634.1 EEQ27792.1 - 0.022 14.4 0.4 0.022 14.4 0.3 2.1 3 0 0 3 3 3 0 zinc-RING finger domain Afi1 PF07792.7 EEQ27792.1 - 0.043 13.8 0.1 0.09 12.7 0.1 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RXT2_N PF08595.6 EEQ27792.1 - 0.073 12.8 6.5 0.17 11.6 4.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Vps39_1 PF10366.4 EEQ27792.1 - 0.13 12.2 0.0 0.44 10.5 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 RPN7 PF10602.4 EEQ27792.1 - 0.13 11.5 0.0 0.39 10.0 0.0 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Coatomer_WDAD PF04053.9 EEQ27792.1 - 0.24 10.1 0.1 2.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region zf-RING_2 PF13639.1 EEQ27792.1 - 0.66 9.8 4.3 0.62 9.9 0.9 2.4 2 0 0 2 2 2 0 Ring finger domain Nop14 PF04147.7 EEQ27792.1 - 7.4 4.3 7.4 13 3.5 5.1 1.3 1 0 0 1 1 1 0 Nop14-like family MTBP_C PF14920.1 EEQ27793.1 - 0.22 10.9 7.3 0.29 10.5 5.0 1.1 1 0 0 1 1 1 0 MDM2-binding Herpes_BLLF1 PF05109.8 EEQ27793.1 - 0.39 8.6 29.4 0.42 8.5 20.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Pex14_N PF04695.8 EEQ27793.1 - 2.1 8.3 6.2 1.2 9.1 2.7 1.6 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4106 PF13388.1 EEQ27793.1 - 5.5 5.8 9.1 7.4 5.4 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Golgin_A5 PF09787.4 EEQ27793.1 - 5.7 5.3 6.6 7.2 5.0 4.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF605 PF04652.11 EEQ27793.1 - 7.4 5.8 10.4 8.7 5.6 7.2 1.0 1 0 0 1 1 1 0 Vta1 like CP2 PF04516.10 EEQ27794.1 - 1.7e-81 272.7 0.1 2.7e-81 272.1 0.1 1.3 1 0 0 1 1 1 1 CP2 transcription factor Metallopep PF12044.3 EEQ27795.1 - 7.8e-120 400.1 0.0 4.5e-60 203.2 0.0 2.2 1 1 0 2 2 2 2 Putative peptidase family BAF1_ABF1 PF04684.8 EEQ27795.1 - 0.38 9.5 0.1 42 2.8 0.1 2.8 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor GST_N_3 PF13417.1 EEQ27797.1 - 4.5e-10 39.6 0.1 8.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ27797.1 - 3.7e-09 36.4 0.1 9.7e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ27797.1 - 9.1e-09 35.0 0.1 2.5e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEQ27797.1 - 0.00069 19.7 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ27797.1 - 0.0032 17.3 0.1 0.006 16.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4589 PF15252.1 EEQ27797.1 - 0.086 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) DJ-1_PfpI PF01965.19 EEQ27798.1 - 1.6e-20 73.0 0.0 2.8e-20 72.2 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EEQ27798.1 - 0.00018 20.9 0.0 0.00086 18.7 0.0 2.2 2 1 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family DNA_ligase_A_M PF01068.16 EEQ27799.1 - 4.7e-51 173.0 0.0 2.2e-48 164.2 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEQ27799.1 - 1.3e-42 145.5 0.0 2.5e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEQ27799.1 - 1.7e-18 66.7 0.0 6.5e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RINT1_TIP1 PF04437.8 EEQ27800.1 - 1e-163 545.4 0.3 2.8e-163 544.0 0.0 1.8 2 0 0 2 2 2 1 RINT-1 / TIP-1 family WEMBL PF05701.6 EEQ27800.1 - 0.01 14.3 7.8 0.01 14.3 4.7 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF883 PF05957.8 EEQ27800.1 - 0.18 12.2 3.1 1.2 9.5 1.0 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Tweety PF04906.8 EEQ27800.1 - 0.66 8.3 2.7 0.72 8.2 0.0 2.0 1 1 1 2 2 2 0 Tweety ApoLp-III PF07464.6 EEQ27800.1 - 2 8.4 9.3 1.2 9.2 3.8 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Pyridoxal_deC PF00282.14 EEQ27801.1 - 5.8e-76 255.3 0.0 1.1e-75 254.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PUF PF00806.14 EEQ27801.1 - 1.8e-14 52.3 0.0 1.1 8.9 0.0 8.4 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat Aminotran_5 PF00266.14 EEQ27801.1 - 3.1e-05 22.8 0.0 5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEQ27801.1 - 4.2e-05 22.8 0.0 8.1e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Glyoxalase_2 PF12681.2 EEQ27802.1 - 3.2e-15 56.6 0.0 4.2e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EEQ27802.1 - 2.5e-07 30.7 0.1 4.1e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.20 EEQ27803.1 - 4.8e-22 78.6 0.3 6.9e-22 78.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ27803.1 - 3.9e-15 56.2 0.0 5.5e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ27803.1 - 4.2e-06 26.5 0.3 8.7e-06 25.5 0.2 1.4 1 1 0 1 1 1 1 KR domain Bacteriocin_IId PF09221.5 EEQ27803.1 - 6.5 6.7 9.3 0.29 11.0 0.7 2.9 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like WD40 PF00400.27 EEQ27804.1 - 9.2e-34 114.1 8.8 1.8e-08 33.9 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 EEQ27804.1 - 6.2e-29 99.8 13.2 1.1e-28 99.1 9.2 1.4 1 0 0 1 1 1 1 Sof1-like domain Cytochrom_D1 PF02239.11 EEQ27804.1 - 0.022 13.0 0.1 0.13 10.5 0.1 2.1 2 1 0 2 2 2 0 Cytochrome D1 heme domain PCI PF01399.22 EEQ27805.1 - 7.2e-19 68.0 1.1 1.3e-18 67.1 0.1 2.0 2 1 0 2 2 2 1 PCI domain TPR_14 PF13428.1 EEQ27805.1 - 0.00011 22.5 7.1 0.14 12.9 0.2 5.4 5 2 1 6 6 6 1 Tetratricopeptide repeat DDRGK PF09756.4 EEQ27805.1 - 0.00013 21.4 0.1 0.00032 20.1 0.1 1.6 1 0 0 1 1 1 1 DDRGK domain TPR_8 PF13181.1 EEQ27805.1 - 0.00048 19.7 5.6 24 4.9 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ27805.1 - 0.0005 19.9 12.5 0.45 10.4 0.4 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ27805.1 - 0.0008 18.9 1.9 4.3 7.1 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ27805.1 - 0.0017 18.1 5.1 46 4.2 0.2 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ27805.1 - 0.007 16.0 6.7 1.4 8.9 0.0 5.1 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ27805.1 - 0.02 15.5 14.6 0.17 12.5 0.7 5.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ27805.1 - 0.034 14.5 3.2 1.6 9.3 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ27805.1 - 0.048 14.1 11.1 0.33 11.5 0.1 5.5 6 1 0 6 6 5 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EEQ27805.1 - 0.058 13.1 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 Prefoldin_2 PF01920.15 EEQ27805.1 - 0.11 12.2 1.2 0.58 9.9 0.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit TPR_19 PF14559.1 EEQ27805.1 - 0.36 11.1 10.4 0.35 11.2 0.5 4.7 4 2 0 4 4 3 0 Tetratricopeptide repeat SWIB PF02201.13 EEQ27806.1 - 2.5e-17 62.3 0.0 4.8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain TRAM_LAG1_CLN8 PF03798.11 EEQ27807.1 - 1.3e-46 158.6 17.0 1.9e-46 158.1 11.8 1.2 1 0 0 1 1 1 1 TLC domain LPP PF04728.8 EEQ27808.1 - 1.7e-07 30.9 2.6 0.052 13.3 0.2 4.7 1 1 3 4 4 4 4 Lipoprotein leucine-zipper DUF2229 PF09989.4 EEQ27808.1 - 0.17 11.3 0.0 0.17 11.3 0.0 5.4 6 1 0 6 6 6 0 CoA enzyme activase uncharacterised domain (DUF2229) Ribosomal_L27e PF01777.13 EEQ27809.1 - 5.1e-38 129.0 3.1 6.6e-38 128.7 2.2 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EEQ27809.1 - 0.00029 20.4 0.6 0.00029 20.4 0.4 2.0 2 1 0 2 2 2 1 KOW motif SMAP PF15477.1 EEQ27809.1 - 0.035 14.3 2.3 0.078 13.2 1.6 1.6 1 1 0 1 1 1 0 Small acidic protein family Band_7 PF01145.20 EEQ27811.1 - 5.7e-27 94.7 1.8 9.5e-27 94.0 1.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PHD PF00628.24 EEQ27812.1 - 6.2e-07 29.0 9.7 1.2e-06 28.1 6.7 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EEQ27812.1 - 0.11 12.2 7.9 0.28 10.9 5.5 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_3 PF13922.1 EEQ27812.1 - 0.13 12.4 3.5 0.63 10.3 2.4 2.2 1 1 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 EEQ27812.1 - 0.33 10.2 10.4 0.061 12.6 3.9 2.2 2 1 0 2 2 2 0 PHD-finger CoA_transf_3 PF02515.12 EEQ27813.1 - 7e-60 201.5 0.0 1.3e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.12 EEQ27814.1 - 2.2e-38 130.0 0.1 2e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Brix PF04427.13 EEQ27815.1 - 6.7e-57 192.2 0.7 9.1e-57 191.8 0.5 1.1 1 0 0 1 1 1 1 Brix domain DEAD PF00270.24 EEQ27816.1 - 8.4e-47 158.8 0.0 1.2e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ27816.1 - 3.6e-26 90.8 0.0 7.7e-26 89.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ27816.1 - 0.00093 19.0 0.0 0.003 17.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EEQ27816.1 - 0.028 14.1 0.3 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain PGM_PMM_I PF02878.11 EEQ27817.1 - 4e-17 61.9 0.4 6.9e-08 32.0 0.0 3.1 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EEQ27817.1 - 2.7e-15 56.5 0.4 1.3e-14 54.3 0.1 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEQ27817.1 - 2.5e-10 40.1 0.3 8.2e-10 38.5 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EEQ27817.1 - 0.00072 19.5 0.4 0.0023 17.9 0.3 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Per1 PF04080.8 EEQ27818.1 - 2.3e-108 361.6 10.5 3.6e-108 361.0 7.3 1.3 1 0 0 1 1 1 1 Per1-like Orai-1 PF07856.7 EEQ27818.1 - 5.3 6.5 7.2 1.1 8.8 1.5 2.2 3 0 0 3 3 3 0 Mediator of CRAC channel activity Methyltransf_31 PF13847.1 EEQ27819.1 - 1.2e-12 47.7 0.0 1.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEQ27819.1 - 6.2e-11 41.9 0.0 9.3e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EEQ27819.1 - 2.1e-10 41.1 0.0 4.6e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ27819.1 - 2.8e-09 37.0 0.0 6.5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EEQ27819.1 - 1.4e-07 30.7 0.0 3e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EEQ27819.1 - 1.6e-07 31.7 0.0 3.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EEQ27819.1 - 3.1e-06 26.1 0.0 4.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 EEQ27819.1 - 3.2e-06 26.9 0.0 7.6e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ27819.1 - 1.3e-05 25.4 0.0 4.6e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEQ27819.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EEQ27819.1 - 1.5e-05 24.4 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EEQ27819.1 - 0.00021 21.6 0.0 0.00043 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEQ27819.1 - 0.00035 20.6 0.0 0.00068 19.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EEQ27819.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EEQ27819.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ27819.1 - 0.022 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 EEQ27819.1 - 0.039 13.4 0.2 0.065 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 EEQ27819.1 - 0.061 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.13 EEQ27819.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TehB PF03848.9 EEQ27819.1 - 0.067 12.3 0.1 0.45 9.6 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TehB MaoC_dehydratas PF01575.14 EEQ27820.1 - 4.5e-26 90.6 0.0 7.4e-26 89.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EEQ27820.1 - 1.4e-09 37.8 0.0 2.7e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase TauD PF02668.11 EEQ27821.1 - 1e-38 133.5 0.0 1.4e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EEQ27821.1 - 0.073 13.5 0.0 2.2 8.8 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily AAA PF00004.24 EEQ27822.1 - 1.4e-40 138.5 0.0 3.2e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ27822.1 - 0.00012 22.1 0.2 0.0081 16.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EEQ27822.1 - 0.00014 21.0 0.0 0.00052 19.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EEQ27822.1 - 0.00029 20.5 2.1 0.00079 19.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ27822.1 - 0.00087 19.4 1.3 0.022 14.9 0.0 2.8 2 1 0 3 3 2 1 AAA domain PhoH PF02562.11 EEQ27822.1 - 0.0013 17.9 0.3 0.041 13.1 0.1 2.5 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 EEQ27822.1 - 0.0016 17.4 1.7 0.03 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EEQ27822.1 - 0.0029 17.5 3.4 0.0049 16.7 0.0 3.0 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EEQ27822.1 - 0.0064 15.6 0.1 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EEQ27822.1 - 0.0086 15.9 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ27822.1 - 0.013 15.2 0.3 0.032 13.9 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EEQ27822.1 - 0.019 14.3 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EEQ27822.1 - 0.037 13.4 1.3 0.44 9.9 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EEQ27822.1 - 0.16 12.7 0.1 0.16 12.7 0.1 3.2 2 2 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EEQ27822.1 - 0.51 9.8 0.0 0.51 9.8 0.0 2.8 2 2 0 2 2 1 0 AAA domain F-box-like PF12937.2 EEQ27823.1 - 0.0078 15.9 1.8 0.032 13.9 1.3 2.1 1 1 0 1 1 1 1 F-box-like Pkinase PF00069.20 EEQ27824.1 - 1.3e-70 237.5 0.0 1.8e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27824.1 - 1.8e-31 109.1 0.0 4e-31 108.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEQ27824.1 - 1.6e-11 44.5 1.8 2.9e-11 43.7 0.1 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEQ27824.1 - 3e-10 39.5 0.0 5.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ27824.1 - 0.0066 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEQ27824.1 - 0.051 12.9 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EEQ27824.1 - 0.23 10.4 0.1 0.4 9.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CRC_subunit PF08624.5 EEQ27825.1 - 2.5e-57 192.6 0.1 3.7e-57 192.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Cyclin PF08613.6 EEQ27826.1 - 5.7e-12 46.2 0.0 9.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Caps_synth_GfcC PF06251.6 EEQ27826.1 - 0.045 12.9 8.4 0.075 12.1 5.8 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC DUF4557 PF15101.1 EEQ27826.1 - 0.51 10.1 7.7 0.84 9.4 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SseC PF04888.7 EEQ27826.1 - 6.8 5.9 14.8 10 5.3 10.3 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DAG1 PF05454.6 EEQ27826.1 - 9.3 5.3 6.8 16 4.5 4.7 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4366 PF14283.1 EEQ27827.1 - 0.029 13.7 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Abhydrolase_6 PF12697.2 EEQ27828.1 - 1.9e-12 47.6 0.0 3.7e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ27828.1 - 1.4e-07 31.3 0.0 3e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ27828.1 - 0.0051 16.0 0.1 2.8 7.1 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EEQ27828.1 - 0.015 14.8 0.1 0.13 11.8 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EEQ27828.1 - 0.095 11.9 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EEQ27828.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF2305 PF10230.4 EEQ27828.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Fungal_trans_2 PF11951.3 EEQ27829.1 - 1.7e-07 30.2 1.7 2.9e-07 29.4 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ27829.1 - 2.6e-07 30.4 6.8 6.3e-07 29.1 4.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.17 EEQ27830.1 - 1.6e-33 116.0 0.0 3e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EEQ27830.1 - 9.8e-06 25.1 0.1 2.9e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PBP1_TM PF14812.1 EEQ27830.1 - 0.9 9.8 14.3 1.3 9.3 1.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dor1 PF04124.7 EEQ27831.1 - 1.1e-46 158.8 5.5 1.6e-36 125.4 2.1 2.5 1 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 EEQ27831.1 - 0.0069 16.1 0.3 0.024 14.4 0.2 2.0 1 0 0 1 1 1 1 Vps51/Vps67 RIC1 PF07064.8 EEQ27831.1 - 0.012 15.0 1.2 0.023 14.1 0.1 1.9 2 0 0 2 2 2 0 RIC1 Sec8_exocyst PF04048.9 EEQ27831.1 - 1.8 8.1 7.9 0.17 11.5 0.2 3.0 5 0 0 5 5 5 0 Sec8 exocyst complex component specific domain EAF PF09816.4 EEQ27832.1 - 5.2e-20 71.4 0.0 1.1e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.18 EEQ27833.1 - 1.5e-15 56.8 0.1 2.9e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEQ27833.1 - 4.3e-07 29.8 0.1 3.9e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EEQ27833.1 - 0.0026 17.5 1.3 0.081 12.7 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat BSP_II PF05432.6 EEQ27833.1 - 1 8.5 10.2 1.5 8.0 7.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PK PF00224.16 EEQ27834.1 - 0.11 11.1 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Methyltransf_23 PF13489.1 EEQ27835.1 - 1.3e-20 73.6 0.0 2e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ27835.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ27835.1 - 0.0019 18.6 0.0 0.0037 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27835.1 - 0.0045 17.4 0.0 0.022 15.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DAO PF01266.19 EEQ27836.1 - 1.9e-53 181.6 0.2 2.6e-53 181.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ27836.1 - 2.3e-06 27.6 0.1 0.00083 19.2 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ27836.1 - 4.5e-06 26.5 0.1 0.12 12.1 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.17 EEQ27836.1 - 1.1e-05 24.4 0.1 0.00014 20.8 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EEQ27836.1 - 2.9e-05 23.0 1.6 0.11 11.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEQ27836.1 - 3.1e-05 23.9 0.0 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEQ27836.1 - 0.0013 17.4 0.2 0.23 10.0 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EEQ27836.1 - 0.0044 15.9 0.0 0.038 12.9 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EEQ27836.1 - 0.037 14.4 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EEQ27836.1 - 0.068 12.3 0.0 1.3 8.1 0.0 2.4 3 0 0 3 3 3 0 GMC oxidoreductase FAD_binding_3 PF01494.14 EEQ27836.1 - 0.11 11.5 0.1 0.28 10.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 EEQ27836.1 - 0.11 12.5 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TBP PF00352.16 EEQ27837.1 - 4.4e-70 231.0 0.1 4.1e-35 119.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EEQ27837.1 - 7.5e-05 22.7 0.1 0.44 10.6 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) ETF_QO PF05187.8 EEQ27838.1 - 6.4e-45 151.6 0.0 1e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EEQ27838.1 - 4.3e-05 22.5 0.0 0.032 13.1 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ27838.1 - 0.0038 17.2 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain RRM_1 PF00076.17 EEQ27839.1 - 2.4e-15 55.8 1.4 1.1e-07 31.4 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ27839.1 - 4.8e-11 42.4 0.2 0.00014 21.7 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ27839.1 - 7.1e-11 41.7 0.1 6.4e-05 22.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FolB PF02152.13 EEQ27840.1 - 2.8e-22 78.9 0.2 8.7e-18 64.5 0.1 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase Pkinase PF00069.20 EEQ27841.1 - 1.7e-65 220.7 0.0 2.1e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27841.1 - 5.9e-29 100.9 0.0 7.9e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ27841.1 - 0.066 12.9 0.8 2.2 7.9 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.19 EEQ27841.1 - 0.083 13.4 0.6 0.23 11.9 0.4 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Ndc80_HEC PF03801.8 EEQ27843.1 - 7.5e-63 210.7 0.2 1.8e-62 209.5 0.1 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family HSBP1 PF06825.7 EEQ27843.1 - 0.0036 16.8 4.9 0.12 12.0 1.0 3.7 3 1 0 3 3 3 1 Heat shock factor binding protein 1 NPV_P10 PF05531.7 EEQ27843.1 - 0.5 10.6 14.6 22 5.3 1.6 4.6 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EEQ27843.1 - 1.9 8.2 45.3 0.016 14.9 5.7 3.9 2 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein Pex14_N PF04695.8 EEQ27844.1 - 8.7e-42 142.3 0.1 8.7e-42 142.3 0.0 2.8 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.3 EEQ27844.1 - 0.0071 13.7 2.3 0.01 13.2 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) zf-C4H2 PF10146.4 EEQ27844.1 - 0.015 15.3 0.9 0.029 14.4 0.6 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein IncA PF04156.9 EEQ27844.1 - 0.032 13.8 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 IncA protein UreF PF01730.11 EEQ27844.1 - 1.7 8.7 5.9 10 6.2 0.8 2.9 3 0 0 3 3 3 0 UreF ABC_tran PF00005.22 EEQ27846.1 - 2.4e-33 115.3 0.0 5.5e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EEQ27846.1 - 4.7e-16 59.0 0.8 4.7e-16 59.0 0.6 2.4 2 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EEQ27846.1 - 8.6e-05 21.8 0.3 0.0068 15.6 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ27846.1 - 0.00038 20.5 0.5 0.14 12.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EEQ27846.1 - 0.0086 16.4 2.3 0.043 14.1 0.7 2.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EEQ27846.1 - 0.013 15.0 0.4 0.033 13.7 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 EEQ27846.1 - 0.027 14.3 0.4 0.21 11.5 0.0 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EEQ27846.1 - 0.046 12.9 0.0 0.088 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEQ27846.1 - 0.051 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EEQ27846.1 - 0.062 13.4 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain TTL PF03133.10 EEQ27848.1 - 2.2e-53 181.1 0.0 3.1e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EEQ27848.1 - 2.6e-43 147.6 0.0 3.7e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 EEQ27848.1 - 0.0067 16.1 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EEQ27848.1 - 0.095 11.4 0.0 0.24 10.1 0.0 1.6 2 0 0 2 2 2 0 YheC/D like ATP-grasp Seipin PF06775.9 EEQ27849.1 - 3.7e-57 193.0 0.1 5.5e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Aph-1 PF06105.7 EEQ27849.1 - 0.0015 17.8 6.4 0.0026 17.0 4.5 1.3 1 0 0 1 1 1 1 Aph-1 protein DUF2303 PF10065.4 EEQ27849.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) Not1 PF04054.10 EEQ27850.1 - 4.2e-139 463.6 0.3 4.2e-139 463.6 0.2 2.4 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EEQ27850.1 - 2.1e-50 170.2 1.2 4.6e-50 169.1 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) SH3_1 PF00018.23 EEQ27851.1 - 7.9e-13 47.5 0.2 1.6e-12 46.5 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EEQ27851.1 - 3.5e-10 39.1 0.0 7.8e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EEQ27851.1 - 6.1e-10 38.5 0.0 1.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 EEQ27851.1 - 0.00027 21.0 0.2 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Tic20 PF09685.5 EEQ27852.1 - 4e-07 29.9 1.6 5.3e-07 29.5 1.1 1.2 1 0 0 1 1 1 1 Tic20-like protein DASH_Duo1 PF08651.5 EEQ27853.1 - 1.1e-29 101.8 0.2 1.7e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 PEARLI-4 PF05278.7 EEQ27853.1 - 0.0035 16.7 4.2 0.007 15.7 2.9 1.4 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) DUF745 PF05335.8 EEQ27853.1 - 0.0088 15.5 10.7 0.015 14.8 7.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Macoilin PF09726.4 EEQ27853.1 - 2.7 6.1 12.3 3.4 5.8 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein U79_P34 PF03064.11 EEQ27853.1 - 7.3 6.0 12.1 1.7 8.1 6.0 1.6 2 0 0 2 2 2 0 HSV U79 / HCMV P34 ATP-synt_E PF05680.7 EEQ27853.1 - 9.8 6.2 9.2 2.4 8.1 3.8 1.9 2 0 0 2 2 2 0 ATP synthase E chain MAGUK_N_PEST PF10608.4 EEQ27854.1 - 0.22 11.9 5.2 0.87 10.0 0.1 3.4 3 1 0 3 3 3 0 Polyubiquitination (PEST) N-terminal domain of MAGUK zf-primase PF09329.6 EEQ27855.1 - 4.2e-20 71.0 0.4 7.4e-20 70.2 0.3 1.4 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.5 EEQ27856.1 - 3.3e-89 299.0 5.5 4.4e-89 298.6 3.8 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Iron_permease PF04120.7 EEQ27856.1 - 0.013 15.0 0.9 0.12 11.9 0.0 2.4 2 0 0 2 2 2 0 Low affinity iron permease Selenoprotein_S PF06936.6 EEQ27856.1 - 4.7 6.6 9.2 0.39 10.2 2.7 1.8 2 0 0 2 2 2 0 Selenoprotein S (SelS) OAD_gamma PF04277.8 EEQ27856.1 - 7.4 7.0 10.0 13 6.2 1.1 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain GalKase_gal_bdg PF10509.4 EEQ27857.1 - 2.6e-19 68.2 0.0 5.2e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EEQ27857.1 - 9.2e-15 54.6 0.0 2.6e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EEQ27857.1 - 2.8e-12 46.4 1.2 7.5e-12 45.1 0.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain TPP_enzyme_N PF02776.13 EEQ27858.1 - 1.6e-56 190.4 0.1 6.8e-56 188.4 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEQ27858.1 - 1.2e-48 164.5 0.5 3.4e-46 156.6 0.0 3.1 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEQ27858.1 - 1.5e-38 131.6 0.3 5.1e-38 129.9 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EEQ27858.1 - 0.018 14.5 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PhnA_Zn_Ribbon PF08274.7 EEQ27859.1 - 0.0033 17.1 0.7 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 PhnA Zinc-Ribbon RINGv PF12906.2 EEQ27859.1 - 0.036 14.1 1.4 0.089 12.8 1.0 1.7 1 0 0 1 1 1 0 RING-variant domain PsbK PF02533.10 EEQ27859.1 - 0.96 9.4 4.6 0.91 9.5 0.4 2.5 2 0 0 2 2 2 0 Photosystem II 4 kDa reaction centre component MRP-L28 PF09812.4 EEQ27860.1 - 2.9e-07 30.4 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PriCT_2 PF08707.6 EEQ27860.1 - 0.084 12.7 0.3 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) Ras PF00071.17 EEQ27861.1 - 3.7e-47 159.7 0.0 4.3e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ27861.1 - 2.3e-16 60.3 0.0 3.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ27861.1 - 2.4e-06 26.9 0.0 3.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ27861.1 - 0.0033 16.6 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEQ27861.1 - 0.017 14.2 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EEQ27861.1 - 0.018 14.5 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NST1 PF13945.1 EEQ27862.1 - 6e-73 244.9 3.1 6e-73 244.9 2.1 4.8 3 2 2 5 5 5 1 Salt tolerance down-regulator Vps35 PF03635.12 EEQ27863.1 - 1.6e-79 267.9 0.3 1.9e-79 267.7 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Vps35 PF03635.12 EEQ27864.1 - 3.2e-170 567.9 4.5 3.9e-170 567.6 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 WD40 PF00400.27 EEQ27866.1 - 0.00045 19.9 3.0 9.2 6.3 0.2 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1749 PF08538.5 EEQ27867.1 - 2.7e-96 322.0 0.0 3.1e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EEQ27867.1 - 1.1e-06 28.6 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ27867.1 - 1.5e-06 27.9 0.0 4e-06 26.6 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EEQ27867.1 - 0.00052 19.6 0.0 0.022 14.3 0.0 2.7 3 0 0 3 3 3 1 Serine hydrolase Abhydrolase_3 PF07859.8 EEQ27867.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.23 EEQ27867.1 - 0.094 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF900 PF05990.7 EEQ27867.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glycos_transf_2 PF00535.21 EEQ27868.1 - 4.6e-34 117.5 0.0 5.6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEQ27868.1 - 1.6e-16 60.7 0.0 2.2e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EEQ27868.1 - 1.1e-10 41.0 0.0 2.1e-10 40.1 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEQ27868.1 - 0.00037 19.8 0.0 0.00052 19.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 TPR_19 PF14559.1 EEQ27869.1 - 2.1e-09 37.5 0.0 0.0009 19.5 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ27869.1 - 0.00053 20.3 0.3 22 6.0 0.0 4.7 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ27869.1 - 0.0014 18.9 0.0 2.9 8.5 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ27869.1 - 0.0015 19.1 0.0 2.6 8.8 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ27869.1 - 0.0051 16.7 0.5 3.8 7.5 0.0 3.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ27869.1 - 0.045 13.6 0.2 33 4.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ27869.1 - 0.056 13.0 0.6 1.1 8.9 0.0 3.0 4 1 1 5 5 5 0 TPR repeat TPR_4 PF07721.9 EEQ27869.1 - 0.066 13.6 0.5 12 6.7 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 EEQ27870.1 - 2e-06 27.5 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEQ27870.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 HlyIII PF03006.15 EEQ27871.1 - 1.5e-59 201.1 13.1 1.7e-59 200.8 9.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related 60KD_IMP PF02096.15 EEQ27871.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.3 1 1 0 1 1 1 0 60Kd inner membrane protein adh_short PF00106.20 EEQ27872.1 - 5.3e-35 120.7 2.4 5.3e-35 120.7 1.7 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ27872.1 - 4e-26 92.2 0.5 7.2e-26 91.4 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ27872.1 - 7.9e-18 64.7 0.6 1.1e-17 64.3 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EEQ27872.1 - 0.0032 17.1 0.6 0.0051 16.4 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 EEQ27872.1 - 0.0098 15.9 0.1 0.02 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AdoHcyase_NAD PF00670.16 EEQ27872.1 - 0.039 13.7 0.8 0.08 12.7 0.5 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_25 PF13649.1 EEQ27872.1 - 0.055 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 EEQ27872.1 - 0.061 13.3 0.2 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Methyltrans_RNA PF04452.9 EEQ27872.1 - 0.066 12.3 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase Polysacc_synt_2 PF02719.10 EEQ27872.1 - 0.093 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase PF00069.20 EEQ27874.1 - 5.6e-61 205.9 0.0 7.3e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27874.1 - 1.8e-33 115.6 0.0 2.2e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ27874.1 - 0.0011 17.9 0.0 0.0024 16.8 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EEQ27874.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EEQ27874.1 - 0.082 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DisA_N PF02457.11 EEQ27875.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding Pkinase PF00069.20 EEQ27877.1 - 2.5e-54 184.1 0.0 3.8e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27877.1 - 6.6e-23 81.1 0.0 4.1e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ27877.1 - 0.012 14.4 0.2 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EEQ27877.1 - 0.076 11.9 0.0 2 7.3 0.0 2.7 2 1 0 2 2 2 0 Kinase-like TMA7 PF09072.5 EEQ27878.1 - 2.5e-24 85.5 21.3 2.8e-24 85.3 14.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Fib_alpha PF08702.5 EEQ27879.1 - 0.0087 16.1 0.8 0.017 15.2 0.6 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Nup54 PF13874.1 EEQ27879.1 - 0.087 12.4 0.6 0.17 11.5 0.4 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.7 EEQ27879.1 - 0.35 10.6 2.1 1.4 8.7 1.7 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EEQ27879.1 - 8.8 5.3 7.5 0.33 10.0 0.8 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF1948 PF09185.5 EEQ27882.1 - 0.052 13.2 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Cyt-b5 PF00173.23 EEQ27885.1 - 7.3e-15 54.5 0.0 1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ish1 PF10281.4 EEQ27886.1 - 2.2e-75 248.2 15.1 3.5e-14 52.5 0.0 7.6 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EEQ27886.1 - 1.1e-07 31.1 0.0 0.37 10.3 0.0 4.8 4 1 0 4 4 4 3 SAP domain HeH PF12949.2 EEQ27886.1 - 4e-07 29.4 0.1 4.7 6.8 0.0 5.2 5 0 0 5 5 5 3 HeH/LEM domain Slx4 PF09494.5 EEQ27886.1 - 6.3e-05 22.6 0.3 13 5.5 0.0 5.4 6 0 0 6 6 6 2 Slx4 endonuclease APC2 PF08672.6 EEQ27886.1 - 0.00046 20.3 2.8 30 4.9 0.0 5.8 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 GFO_IDH_MocA PF01408.17 EEQ27886.1 - 0.047 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PQ-loop PF04193.9 EEQ27887.1 - 8.1e-19 66.9 25.3 5.4e-12 45.0 2.2 3.6 4 0 0 4 4 4 2 PQ loop repeat TrbC PF04956.8 EEQ27887.1 - 0.028 14.4 3.0 0.064 13.2 1.7 1.9 1 1 0 1 1 1 0 TrbC/VIRB2 family Arteri_GP4 PF02497.10 EEQ27887.1 - 0.03 14.2 0.1 0.063 13.1 0.1 1.5 1 1 0 1 1 1 0 Arterivirus glycoprotein ATP-synt_8 PF00895.15 EEQ27887.1 - 0.18 12.0 0.7 4 7.7 0.0 2.7 2 0 0 2 2 2 0 ATP synthase protein 8 Syndecan PF01034.15 EEQ27887.1 - 3 7.5 7.6 0.48 10.1 1.6 2.2 2 0 0 2 2 2 0 Syndecan domain Gly-zipper_Omp PF13488.1 EEQ27889.1 - 0.065 12.8 3.1 0.11 12.0 2.1 1.3 1 0 0 1 1 1 0 Glycine zipper DUF2951 PF11166.3 EEQ27889.1 - 0.22 11.3 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) FAD_binding_4 PF01565.18 EEQ27891.1 - 4.7e-22 77.9 1.7 7.6e-22 77.2 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ27891.1 - 9.6e-07 28.6 0.1 1.7e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3210 PF11489.3 EEQ27892.1 - 1.5e-151 506.5 72.4 1.5e-151 506.5 50.2 2.5 2 1 0 3 3 3 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 EEQ27893.1 - 1.3e-26 92.7 13.5 8.8e-25 86.8 9.3 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Polysacc_synt PF01943.12 EEQ27893.1 - 0.038 13.2 6.9 0.05 12.8 4.8 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Cytochrom_B558a PF05038.8 EEQ27893.1 - 0.19 11.3 0.9 0.26 10.8 0.1 1.5 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit NTF2 PF02136.15 EEQ27894.1 - 2.7e-31 108.3 0.1 3e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 EEQ27894.1 - 0.082 11.9 0.1 0.12 11.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Mtr2 PF10429.4 EEQ27894.1 - 0.1 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Surp PF01805.15 EEQ27895.1 - 8.7e-17 60.5 0.0 1.9e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Surp module DUF1765 PF08578.5 EEQ27896.1 - 2.3e-40 137.5 0.1 4.6e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.4 EEQ27898.1 - 1.4e-24 85.5 2.0 1.9e-24 85.1 1.4 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EEQ27898.1 - 0.0017 18.2 0.1 0.0024 17.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.14 EEQ27899.1 - 4.2e-38 128.9 0.0 8.3e-20 70.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EEQ27899.1 - 3.1e-10 39.2 1.0 3.1e-10 39.2 0.7 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.2 EEQ27899.1 - 0.095 12.5 1.5 0.37 10.6 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon RB_B PF01857.15 EEQ27899.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Rubredoxin PF00301.15 EEQ27899.1 - 0.38 10.6 4.5 2.4 8.1 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin TFR_dimer PF04253.10 EEQ27900.1 - 1.9e-23 82.3 0.0 3.8e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EEQ27900.1 - 1.4e-11 44.4 0.0 6.6e-11 42.2 0.0 1.9 1 1 1 2 2 2 1 Peptidase family M28 PA PF02225.17 EEQ27900.1 - 2.1e-08 33.7 0.1 4.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 PA domain APH PF01636.18 EEQ27903.1 - 1.9e-08 34.3 0.8 0.001 18.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEQ27903.1 - 7e-06 25.2 1.8 8.3e-05 21.7 0.2 2.1 1 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEQ27903.1 - 2.3e-05 23.8 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.6 EEQ27903.1 - 0.0014 17.9 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 EEQ27903.1 - 0.0091 15.5 0.1 1.1 8.7 0.1 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ27903.1 - 0.048 12.8 0.3 0.079 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein kinase domain HMG_CoA_synt_C PF08540.5 EEQ27904.1 - 7.5e-102 340.6 0.1 9.3e-102 340.2 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EEQ27904.1 - 4.6e-94 312.8 0.1 7.3e-94 312.1 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 EEQ27904.1 - 0.053 12.7 0.3 0.34 10.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) GFO_IDH_MocA PF01408.17 EEQ27906.1 - 1.6e-11 44.7 0.0 3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEQ27906.1 - 0.0063 16.2 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.11 EEQ27907.1 - 9e-34 115.9 0.1 1.3e-33 115.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EEQ27907.1 - 4.2e-24 84.7 0.0 7.6e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EEQ27907.1 - 9.5e-16 58.0 0.0 2.2e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEQ27907.1 - 1.4e-10 41.0 0.0 3.2e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 EEQ27908.1 - 2.9e-25 89.4 0.0 3.3e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF2721 PF11026.3 EEQ27909.1 - 4.5 6.9 12.5 0.049 13.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Sugar_tr PF00083.19 EEQ27911.1 - 3.2e-87 292.9 22.5 3.2e-87 292.9 15.6 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ27911.1 - 4.2e-12 45.4 43.5 2.2e-06 26.6 16.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily UAA PF08449.6 EEQ27911.1 - 0.0023 16.8 0.6 0.0055 15.6 0.4 1.6 1 0 0 1 1 1 1 UAA transporter family Piwi PF02171.12 EEQ27912.1 - 8.9e-68 228.4 0.0 1.7e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EEQ27912.1 - 2.5e-14 52.7 1.3 4.3e-14 51.9 0.9 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EEQ27912.1 - 3.4e-14 51.9 1.0 5.3e-14 51.3 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) DUF3611 PF12263.3 EEQ27914.1 - 0.074 12.4 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Y_phosphatase PF00102.22 EEQ27915.1 - 1.2e-54 185.1 0.0 2.5e-54 184.1 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EEQ27915.1 - 0.00082 19.4 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EEQ27915.1 - 0.0052 17.0 0.0 0.0099 16.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EEQ27915.1 - 0.009 15.6 0.2 0.027 14.0 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TFIIA PF03153.8 EEQ27915.1 - 0.055 13.3 15.9 0.085 12.7 11.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.6 EEQ27915.1 - 8.7 5.7 24.2 14 5.0 16.8 1.3 1 0 0 1 1 1 0 PPP4R2 VanZ PF04892.7 EEQ27916.1 - 2.7e-10 40.2 0.3 3.6e-10 39.8 0.2 1.2 1 0 0 1 1 1 1 VanZ like family DUF4383 PF14325.1 EEQ27916.1 - 0.031 14.3 1.5 0.12 12.3 1.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) Bromodomain PF00439.20 EEQ27917.1 - 1.1e-19 70.1 2.4 2.2e-19 69.1 0.2 2.6 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.8 EEQ27917.1 - 1.8e-08 33.9 0.0 4.6e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated NADH_Oxid_Nqo15 PF11497.3 EEQ27917.1 - 0.063 13.0 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 DUF883 PF05957.8 EEQ27917.1 - 4.6 7.7 7.1 45 4.5 0.3 3.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TPP_enzyme_N PF02776.13 EEQ27918.1 - 2.4e-33 115.0 0.0 3.4e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEQ27918.1 - 2.9e-24 85.3 0.0 3e-23 82.0 0.0 2.3 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEQ27918.1 - 1.1e-14 54.2 0.0 2.7e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EEQ27918.1 - 0.0037 16.0 0.0 0.0071 15.1 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component THUMP PF02926.12 EEQ27919.1 - 8.3e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 THUMP domain Lgl_C PF08596.5 EEQ27920.1 - 4.3e-91 305.3 0.0 5.4e-57 193.0 0.0 2.7 1 1 1 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EEQ27920.1 - 0.039 13.8 0.8 38 4.3 0.0 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat bZIP_1 PF00170.16 EEQ27923.1 - 3.4e-06 26.9 6.8 5.7e-06 26.1 4.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ27923.1 - 0.0062 16.3 6.7 0.015 15.0 4.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper DUF4407 PF14362.1 EEQ27923.1 - 0.29 10.0 2.1 0.55 9.1 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Stm1_N PF09598.5 EEQ27924.1 - 1.8e-13 50.9 10.9 1.8e-13 50.9 7.5 4.6 3 1 0 3 3 3 1 Stm1 DUF1793 PF08760.6 EEQ27926.1 - 7.6e-72 240.7 0.0 1.3e-71 239.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) tRNA-synt_1c PF00749.16 EEQ27927.1 - 2e-97 325.6 0.0 2.8e-97 325.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEQ27927.1 - 2.4e-40 138.0 0.2 3.9e-40 137.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EEQ27927.1 - 1.9e-08 34.6 0.1 6.2e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEQ27927.1 - 0.0029 17.5 0.0 0.0075 16.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ27927.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DEAD PF00270.24 EEQ27931.1 - 1.6e-39 135.1 0.0 3.7e-39 133.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ27931.1 - 6.5e-26 90.0 0.1 1.2e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ27931.1 - 0.00023 20.0 0.0 0.00045 19.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EEQ27931.1 - 0.0072 16.1 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HCO3_cotransp PF00955.16 EEQ27932.1 - 8.5e-61 206.1 18.7 2.2e-29 102.5 1.5 3.0 2 1 1 3 3 3 3 HCO3- transporter family zf-CCHC PF00098.18 EEQ27933.1 - 3e-11 42.6 10.0 3.7e-05 23.4 2.1 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EEQ27933.1 - 1.1e-08 34.6 0.2 2.1e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EEQ27933.1 - 2.2e-06 27.2 6.5 0.00058 19.5 1.9 2.7 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EEQ27933.1 - 1.4e-05 24.6 0.2 3.1e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EEQ27933.1 - 0.00037 20.0 6.2 0.15 11.7 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EEQ27933.1 - 0.0093 15.6 9.7 0.41 10.3 0.5 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.1 EEQ27933.1 - 0.036 13.5 6.5 0.056 12.9 0.2 2.9 1 1 1 2 2 2 0 Zinc knuckle GST_N_3 PF13417.1 EEQ27934.1 - 2e-14 53.5 0.0 3.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ27934.1 - 4.7e-11 42.5 0.0 8.8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEQ27934.1 - 8.3e-11 41.9 0.0 1.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ27934.1 - 1.9e-10 40.5 0.0 3.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ27934.1 - 3.2e-10 39.7 0.0 6.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ27934.1 - 5.1e-08 33.2 0.0 9.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ferric_reduct PF01794.14 EEQ27935.1 - 9.1e-19 67.7 10.8 9.1e-19 67.7 7.5 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EEQ27935.1 - 7.6e-18 64.8 0.0 2.3e-15 56.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ27935.1 - 6.1e-15 54.9 0.0 2.5e-14 53.0 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain CLU PF13236.1 EEQ27938.1 - 2.2e-79 265.9 0.0 3.8e-79 265.1 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EEQ27938.1 - 4.1e-53 179.7 0.0 1.2e-52 178.2 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EEQ27938.1 - 2.3e-26 91.7 0.5 1.1e-25 89.5 0.2 2.3 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EEQ27938.1 - 2.4e-26 91.4 1.8 1.2e-10 41.1 0.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ27938.1 - 9.9e-15 53.9 0.0 0.0021 17.9 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ27938.1 - 2.1e-06 27.2 1.5 0.099 12.3 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EEQ27938.1 - 6.5e-05 22.5 4.0 0.29 11.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ27938.1 - 0.001 18.6 1.1 0.59 10.0 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ27938.1 - 0.0068 17.0 0.0 5.1 7.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat FHIPEP PF00771.15 EEQ27938.1 - 0.086 11.1 0.7 1.5 7.0 0.0 2.1 2 0 0 2 2 2 0 FHIPEP family AAA_16 PF13191.1 EEQ27940.1 - 0.0002 21.4 2.3 0.012 15.6 1.6 2.7 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EEQ27940.1 - 0.0011 18.7 0.1 0.0034 17.1 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EEQ27940.1 - 0.0027 17.8 0.0 0.093 12.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EEQ27940.1 - 0.019 13.8 0.0 0.042 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EEQ27940.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEQ27940.1 - 0.077 12.7 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EEQ27940.1 - 0.13 12.7 0.0 0.44 11.0 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_25 PF13481.1 EEQ27940.1 - 0.13 11.6 0.0 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EEQ27940.1 - 0.14 11.6 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HTH_Tnp_Tc3_2 PF01498.13 EEQ27941.1 - 0.054 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Transposase Med10 PF09748.4 EEQ27942.1 - 1.7e-35 121.6 0.1 4.5e-35 120.2 0.1 1.7 1 1 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 EEQ27942.1 - 0.022 14.3 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Peptidase_M28 PF04389.12 EEQ27944.1 - 1.3e-32 112.9 0.1 2.1e-32 112.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.15 EEQ27944.1 - 0.028 14.6 0.1 0.028 14.6 0.1 4.3 4 1 1 5 5 5 0 ATP synthase protein 8 Peptidase_M20 PF01546.23 EEQ27944.1 - 0.092 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 LRR_4 PF12799.2 EEQ27945.1 - 4.2e-13 48.5 4.2 0.1 12.2 0.0 7.3 3 2 4 8 8 8 4 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EEQ27945.1 - 3.1e-12 46.0 2.1 4.9e-10 38.9 0.5 3.0 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EEQ27945.1 - 3.6e-11 42.6 10.3 0.032 14.0 0.5 6.5 3 1 2 6 6 6 4 Leucine rich repeat LRR_6 PF13516.1 EEQ27945.1 - 4.2e-11 41.7 16.1 3.5 7.9 0.0 11.0 13 0 0 13 13 13 4 Leucine Rich repeat LRR_1 PF00560.28 EEQ27945.1 - 2.2e-07 29.9 18.3 3.6 7.9 0.0 10.5 8 4 0 8 8 8 1 Leucine Rich Repeat F-box PF00646.28 EEQ27945.1 - 6.9e-05 22.3 3.6 0.0014 18.2 0.1 3.7 3 0 0 3 3 3 1 F-box domain DUF1699 PF08004.6 EEQ27945.1 - 0.021 14.3 0.7 2.1 7.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) Recep_L_domain PF01030.19 EEQ27945.1 - 0.072 13.0 1.3 25 4.8 0.0 3.8 1 1 2 4 4 4 0 Receptor L domain Adeno_E4_34 PF04528.8 EEQ27945.1 - 2.2 7.8 11.2 0.97 9.0 1.9 3.1 2 1 1 3 3 3 0 Adenovirus early E4 34 kDa protein conserved region AMP-binding PF00501.23 EEQ27946.1 - 2.7e-67 227.0 0.0 3.2e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ27946.1 - 9.3e-16 58.5 0.0 1.8e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L13 PF00572.13 EEQ27947.1 - 1.3e-27 96.3 0.0 2.4e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Metallophos PF00149.23 EEQ27948.1 - 8.5e-11 41.6 2.0 2.9e-08 33.3 0.0 2.5 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ27948.1 - 5.3e-08 32.8 0.1 1e-07 31.9 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.1 EEQ27948.1 - 0.052 11.8 0.0 0.079 11.2 0.0 1.1 1 0 0 1 1 1 0 MutL protein Pyr_redox PF00070.22 EEQ27949.1 - 6.4e-16 58.5 0.0 5.4e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ27949.1 - 1.3e-13 51.2 0.0 6.7e-13 48.9 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ27949.1 - 1.2e-08 35.2 0.0 1.1e-05 25.6 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ27949.1 - 1.2e-07 31.0 0.2 6.9e-05 21.9 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EEQ27949.1 - 0.00094 18.1 0.0 0.55 9.0 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEQ27949.1 - 0.0017 18.1 0.2 5.6 6.7 0.0 3.5 2 1 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EEQ27949.1 - 0.0018 16.9 0.1 0.4 9.2 0.0 2.9 2 1 1 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EEQ27949.1 - 0.015 14.2 0.0 0.89 8.3 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 EEQ27949.1 - 0.074 13.0 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain DnaJ PF00226.26 EEQ27951.1 - 4e-21 74.4 0.5 7.3e-21 73.6 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Adaptin_N PF01602.15 EEQ27952.1 - 1.1e-131 439.7 0.0 2.1e-131 438.8 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EEQ27952.1 - 1.9e-20 73.3 0.0 3.4e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EEQ27952.1 - 9.9e-08 32.1 0.2 0.023 14.9 0.0 4.0 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EEQ27952.1 - 0.00026 20.7 1.1 13 6.1 0.0 4.8 4 1 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EEQ27952.1 - 0.004 17.6 0.2 6.9 7.2 0.0 4.4 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 EEQ27952.1 - 0.013 15.3 3.6 0.017 14.9 0.2 2.9 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 EEQ27952.1 - 0.02 14.4 0.2 0.07 12.7 0.0 1.9 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 EEQ27952.1 - 0.045 13.5 0.1 60 3.6 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat G-patch_2 PF12656.2 EEQ27952.1 - 0.093 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 DExH-box splicing factor binding site MBOAT PF03062.14 EEQ27953.1 - 9e-24 84.1 24.4 3.9e-23 82.0 16.9 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Nuc_sug_transp PF04142.10 EEQ27954.1 - 1.7e-08 33.8 1.1 2.8e-08 33.1 0.7 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EEQ27954.1 - 7.1e-07 29.3 25.7 0.00045 20.2 3.7 3.3 2 1 1 3 3 3 3 EamA-like transporter family UAA PF08449.6 EEQ27954.1 - 2.3e-06 26.7 11.5 5.5e-06 25.5 8.0 1.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEQ27954.1 - 2.4e-06 27.2 15.8 0.0016 18.0 0.2 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EEQ27954.1 - 0.00071 19.7 2.2 0.00071 19.7 1.5 3.6 2 1 2 4 4 4 1 Multidrug resistance efflux transporter DUF3353 PF11833.3 EEQ27954.1 - 0.02 14.3 0.0 0.055 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF2975 PF11188.3 EEQ27954.1 - 2.2 7.9 9.0 0.43 10.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Med15_fungi PF05397.7 EEQ27955.1 - 2.8e-12 46.6 5.3 2.8e-12 46.6 3.6 5.1 5 1 0 5 5 5 1 Mediator complex subunit 15 LMBR1 PF04791.11 EEQ27956.1 - 2.8e-37 128.4 1.1 3.6e-37 128.0 0.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein BAG PF02179.11 EEQ27957.1 - 3.8e-06 26.8 0.2 8.9e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 BAG domain DUF2407 PF10302.4 EEQ27957.1 - 0.0081 16.3 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EEQ27957.1 - 0.085 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Nop14 PF04147.7 EEQ27957.1 - 0.09 10.6 2.2 0.12 10.2 1.5 1.1 1 0 0 1 1 1 0 Nop14-like family Maff2 PF12750.2 EEQ27957.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Maff2 family Sigma70_ner PF04546.8 EEQ27957.1 - 1.8 8.0 8.0 1.1 8.7 3.7 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region F-box PF00646.28 EEQ27958.1 - 0.0015 18.0 0.4 0.0037 16.8 0.3 1.7 1 0 0 1 1 1 1 F-box domain ING PF12998.2 EEQ27959.1 - 9.5e-07 29.0 0.3 2.6e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-C2H2_4 PF13894.1 EEQ27960.1 - 0.025 14.8 1.7 0.025 14.8 1.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ27960.1 - 0.34 11.3 9.5 0.073 13.4 2.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type GHMP_kinases_N PF00288.21 EEQ27960.1 - 1.4 9.0 9.5 0.66 10.0 2.3 3.0 3 0 0 3 3 3 0 GHMP kinases N terminal domain Methyltransf_16 PF10294.4 EEQ27961.1 - 2.6e-09 36.7 0.0 2.8e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EEQ27962.1 - 1.2e-16 61.2 0.0 2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ27962.1 - 2.1e-13 50.1 0.0 1.8e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ27962.1 - 8.5e-06 25.7 0.0 2.5e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ27962.1 - 3.7e-05 24.1 0.0 9.7e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ27962.1 - 0.00014 21.5 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ27962.1 - 0.0016 18.8 0.0 0.003 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ27962.1 - 0.0022 18.4 0.0 0.0047 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EEQ27962.1 - 0.0092 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EEQ27962.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain AMP-binding PF00501.23 EEQ27963.1 - 2.7e-157 523.4 0.0 5.2e-80 268.8 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEQ27963.1 - 1.8e-112 375.0 0.0 1.9e-39 135.2 0.0 4.3 4 2 0 4 4 4 3 Condensation domain PP-binding PF00550.20 EEQ27963.1 - 2.1e-28 98.3 0.2 4.3e-11 42.9 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site Transferase PF02458.10 EEQ27963.1 - 0.19 10.1 0.0 0.39 9.0 0.0 1.4 1 0 0 1 1 1 0 Transferase family GH3 PF03321.8 EEQ27963.1 - 2.7 6.4 4.4 3.1 6.2 0.0 2.7 4 0 0 4 4 4 0 GH3 auxin-responsive promoter ABC_membrane PF00664.18 EEQ27964.1 - 3.1e-85 285.9 46.3 8.4e-47 159.8 14.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ27964.1 - 1.9e-70 235.4 0.1 1.5e-34 119.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ27964.1 - 1.6e-15 56.9 5.1 4.9e-06 25.9 0.6 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ27964.1 - 1.7e-13 51.1 0.9 0.00023 21.2 0.1 4.3 2 2 1 4 4 4 3 AAA domain AAA_16 PF13191.1 EEQ27964.1 - 5.7e-10 39.4 2.0 1.8e-05 24.8 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEQ27964.1 - 4.8e-08 32.4 0.1 0.0037 16.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EEQ27964.1 - 6.8e-08 31.8 0.0 0.012 14.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EEQ27964.1 - 5.7e-07 28.4 1.2 0.0041 15.7 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EEQ27964.1 - 6.8e-07 30.1 0.0 0.00063 20.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEQ27964.1 - 1.1e-05 25.5 1.6 0.035 14.2 0.0 4.0 3 2 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EEQ27964.1 - 6e-05 22.8 0.7 0.28 10.8 0.0 3.9 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EEQ27964.1 - 6.4e-05 22.6 1.0 0.56 9.7 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EEQ27964.1 - 0.00013 22.2 0.0 0.015 15.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 EEQ27964.1 - 0.00024 20.9 0.8 1.6 8.7 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EEQ27964.1 - 0.00043 20.4 0.3 24 5.1 0.0 4.5 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEQ27964.1 - 0.00068 18.7 0.0 0.16 11.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EEQ27964.1 - 0.00082 19.2 0.0 0.099 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEQ27964.1 - 0.0011 18.8 0.1 1.2 9.0 0.0 4.0 4 0 0 4 4 4 1 AAA domain G-alpha PF00503.15 EEQ27964.1 - 0.0056 15.4 0.0 0.15 10.7 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_25 PF13481.1 EEQ27964.1 - 0.007 15.7 0.1 0.95 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EEQ27964.1 - 0.0094 16.2 0.0 4.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EEQ27964.1 - 0.01 14.7 0.0 1.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF3987 PF13148.1 EEQ27964.1 - 0.011 14.3 0.0 0.3 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.18 EEQ27964.1 - 0.012 15.5 0.7 1.2 9.0 0.1 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.13 EEQ27964.1 - 0.013 15.0 0.0 0.71 9.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 EEQ27964.1 - 0.016 14.8 0.0 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EEQ27964.1 - 0.022 14.7 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEQ27964.1 - 0.027 13.9 1.5 1.3 8.4 0.0 3.4 4 0 0 4 4 4 0 AAA-like domain AAA_15 PF13175.1 EEQ27964.1 - 0.035 13.1 0.0 4.6 6.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain APS_kinase PF01583.15 EEQ27964.1 - 0.042 13.5 0.0 4.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EEQ27964.1 - 0.054 13.6 0.1 8.4 6.6 0.0 3.2 4 0 0 4 4 2 0 RNA helicase Rad17 PF03215.10 EEQ27964.1 - 0.081 11.5 0.0 0.99 8.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 EEQ27964.1 - 0.098 11.4 0.0 3.3 6.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Cache_3 PF14827.1 EEQ27964.1 - 0.19 11.6 2.6 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Sensory domain of two-component sensor kinase Dynamin_N PF00350.18 EEQ27964.1 - 0.21 11.3 2.6 14 5.4 0.0 4.4 5 1 0 5 5 5 0 Dynamin family Beta-lactamase PF00144.19 EEQ27965.1 - 1.2e-46 159.2 0.0 1.7e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EEQ27965.1 - 2.3e-07 30.5 0.0 4.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DSPc PF00782.15 EEQ27966.1 - 5.6e-23 80.9 0.0 1.3e-20 73.2 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEQ27966.1 - 0.025 13.9 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2537 PF10801.3 EEQ27968.1 - 6.4 6.9 7.6 0.53 10.4 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Epimerase PF01370.16 EEQ27970.1 - 4e-15 55.9 0.1 3.4e-14 52.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ27970.1 - 8.2e-12 44.4 0.0 2.2e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEQ27970.1 - 3.5e-08 33.6 0.1 1.5e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EEQ27970.1 - 5.1e-08 33.0 0.0 8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ27970.1 - 2.3e-07 30.6 0.0 3.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EEQ27970.1 - 3.8e-07 29.2 0.0 6.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EEQ27970.1 - 0.00095 18.1 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EEQ27970.1 - 0.0037 16.5 0.2 0.037 13.2 0.1 2.2 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EEQ27970.1 - 0.047 12.5 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DSBA PF01323.15 EEQ27971.1 - 2.7e-35 121.6 0.0 3.1e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EEQ27971.1 - 0.003 17.6 0.1 0.0078 16.2 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EEQ27971.1 - 0.016 15.3 0.0 0.62 10.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Pkinase PF00069.20 EEQ27972.1 - 3.8e-27 95.0 0.0 5.2e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27972.1 - 2.4e-10 39.9 0.0 3.7e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ27972.1 - 0.0076 15.2 0.1 1.2 8.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RMP PF14996.1 EEQ27973.1 - 0.016 15.0 4.1 0.032 14.1 2.9 1.7 1 1 0 1 1 1 0 Retinal Maintenance KH_1 PF00013.24 EEQ27974.1 - 7.3e-39 131.2 9.8 1.7e-15 56.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EEQ27974.1 - 2.2e-29 100.5 11.1 1.3e-11 43.8 0.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EEQ27974.1 - 2.7e-10 39.6 8.3 0.00045 19.7 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EEQ27974.1 - 1.6e-08 34.0 3.6 0.054 13.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EEQ27974.1 - 0.0011 18.7 4.1 0.89 9.4 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EEQ27974.1 - 0.016 14.6 0.3 3.3 7.1 0.0 3.1 3 0 0 3 3 3 0 dUTPase Dehydratase_hem PF13816.1 EEQ27975.1 - 3.2e-118 394.3 0.0 3.6e-118 394.1 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EEQ27975.1 - 1.3e-07 31.6 0.0 0.017 15.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) ADH_N PF08240.7 EEQ27976.1 - 9.4e-29 99.3 0.8 1.7e-28 98.5 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ27976.1 - 1.1e-20 73.5 0.0 1.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Yippee-Mis18 PF03226.9 EEQ27977.1 - 6.7e-24 83.7 0.7 7.6e-24 83.5 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 EEQ27977.1 - 0.0028 17.6 1.8 0.024 14.6 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Evr1_Alr PF04777.8 EEQ27977.1 - 0.0078 16.0 2.4 0.39 10.6 0.1 2.1 1 1 1 2 2 2 2 Erv1 / Alr family RIG-I_C-RD PF11648.3 EEQ27977.1 - 0.02 14.7 2.4 0.043 13.6 1.7 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I DUF4451 PF14616.1 EEQ27977.1 - 0.038 13.7 1.7 0.052 13.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Elf1 PF05129.8 EEQ27977.1 - 0.098 12.3 0.7 2.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DiS_P_DiS PF06750.8 EEQ27977.1 - 0.1 12.4 0.4 2.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain HNH_5 PF14279.1 EEQ27977.1 - 0.11 12.5 1.6 2.4 8.2 0.1 2.2 1 1 1 2 2 2 0 HNH endonuclease DZR PF12773.2 EEQ27977.1 - 0.11 12.3 0.6 0.25 11.2 0.4 1.5 1 1 0 1 1 1 0 Double zinc ribbon RabGAP-TBC PF00566.13 EEQ27979.1 - 8.7e-25 87.4 5.4 8.7e-25 87.4 3.7 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain HemY_N PF07219.8 EEQ27979.1 - 0.17 11.4 0.3 14 5.2 0.0 2.4 2 0 0 2 2 2 0 HemY protein N-terminus COesterase PF00135.23 EEQ27981.1 - 2.2e-83 280.8 0.0 2.9e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ27981.1 - 7.5e-07 28.9 0.0 0.00016 21.2 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ27981.1 - 0.041 13.1 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.20 EEQ27982.1 - 1.9e-57 194.3 0.0 2.8e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ27982.1 - 7.8e-20 71.0 0.0 1.4e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ27982.1 - 9.8e-06 24.7 0.0 1.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ27982.1 - 0.00017 20.7 0.0 0.00032 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ27982.1 - 0.00022 21.0 0.1 0.00062 19.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ27982.1 - 0.0021 17.4 0.1 0.0042 16.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 EEQ27982.1 - 0.031 14.6 0.2 2.8 8.3 0.0 3.8 5 1 0 5 5 5 0 PAS domain Choline_kinase PF01633.15 EEQ27982.1 - 0.034 13.7 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase LRR_6 PF13516.1 EEQ27983.1 - 9.8e-13 46.7 14.4 0.026 14.5 0.1 8.4 9 0 0 9 9 9 4 Leucine Rich repeat F-box-like PF12937.2 EEQ27983.1 - 1.9e-11 43.5 0.0 7.7e-11 41.5 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ27983.1 - 3.8e-10 39.1 0.0 1.2e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EEQ27983.1 - 2.1e-08 33.6 9.3 0.0016 18.0 0.1 6.2 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEQ27983.1 - 2.7e-05 23.6 14.2 0.85 9.8 0.1 8.1 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 EEQ27983.1 - 7.8e-05 22.3 7.8 0.64 9.8 0.3 4.6 3 1 2 5 5 5 3 Leucine rich repeat PRANC PF09372.5 EEQ27983.1 - 0.0069 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 PRANC domain LRR_7 PF13504.1 EEQ27983.1 - 0.051 13.7 21.8 0.93 9.9 0.3 7.6 9 0 0 9 9 9 0 Leucine rich repeat DUF2361 PF10153.4 EEQ27984.1 - 4.6e-33 113.7 8.2 4.6e-33 113.7 5.7 2.4 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF573 PF04504.9 EEQ27984.1 - 0.015 15.5 0.2 0.015 15.5 0.2 2.9 2 1 2 4 4 4 0 Protein of unknown function, DUF573 APH PF01636.18 EEQ27986.1 - 3e-09 36.9 0.0 5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ27986.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ27986.1 - 0.084 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF4058 PF13267.1 EEQ27987.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) PTS_2-RNA PF01885.11 EEQ27988.1 - 1.4e-64 216.8 0.0 1.7e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family APH PF01636.18 EEQ27989.1 - 1.4e-14 54.4 0.0 9.9e-13 48.3 0.0 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Alkyl_sulf_dimr PF14863.1 EEQ27990.1 - 6.8e-56 188.4 0.4 2.6e-55 186.5 0.1 2.0 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 EEQ27990.1 - 4.1e-33 114.0 0.1 8.3e-33 113.0 0.1 1.6 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 EEQ27990.1 - 2.6e-23 82.6 0.1 5.3e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEQ27990.1 - 3.3e-06 26.7 0.0 7.5e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain PDEase_II PF02112.10 EEQ27990.1 - 0.023 13.6 0.1 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II TT_ORF1 PF02956.9 EEQ27991.1 - 7.3 4.9 7.0 8.4 4.7 4.8 1.1 1 0 0 1 1 1 0 TT viral orf 1 Stb3 PF10330.4 EEQ27992.1 - 6e-35 118.8 0.0 1e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF605 PF04652.11 EEQ27993.1 - 5.7 6.2 29.5 8.6 5.6 20.4 1.2 1 0 0 1 1 1 0 Vta1 like Mito_carr PF00153.22 EEQ27994.1 - 5.9e-67 221.4 5.4 1.4e-23 82.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kri1 PF05178.7 EEQ27995.1 - 8.1e-30 103.0 21.1 8.1e-30 103.0 14.6 5.3 5 1 1 6 6 6 1 KRI1-like family Kri1_C PF12936.2 EEQ27995.1 - 4.1e-28 97.1 0.2 4.1e-28 97.1 0.2 4.3 2 2 2 4 4 4 1 KRI1-like family C-terminal PH PF00169.24 EEQ27996.1 - 2.1e-07 31.0 0.0 5.3e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 EEQ27996.1 - 0.0071 15.8 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 EEQ27996.1 - 0.0089 16.2 4.8 1.3 9.3 0.1 3.5 2 1 0 2 2 2 2 Pleckstrin homology domain Sen15 PF09631.5 EEQ27997.1 - 8.4e-16 58.0 0.0 1.8e-15 56.9 0.0 1.5 1 1 0 1 1 1 1 Sen15 protein UAA PF08449.6 EEQ27998.1 - 2.9e-70 236.6 8.4 8.1e-70 235.1 5.8 1.6 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EEQ27998.1 - 1.4e-07 30.9 0.2 0.0021 17.2 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 EEQ27998.1 - 5.7e-06 26.3 7.8 5.7e-06 26.3 5.4 3.7 4 1 0 4 4 4 2 EamA-like transporter family EmrE PF13536.1 EEQ27998.1 - 0.0046 17.1 15.6 0.0046 17.1 1.1 2.9 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EEQ27998.1 - 0.98 9.0 22.4 0.19 11.3 5.8 3.2 2 2 0 2 2 2 0 Triose-phosphate Transporter family Rotamase_3 PF13616.1 EEQ27999.1 - 2.5e-16 59.9 0.0 3.8e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EEQ27999.1 - 4.5e-16 59.3 0.0 6.6e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EEQ27999.1 - 0.00039 21.0 0.0 0.00048 20.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF3883 PF13020.1 EEQ27999.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3883) DUF3580 PF12117.3 EEQ28000.1 - 0.11 12.4 1.9 0.24 11.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) DAO PF01266.19 EEQ28002.1 - 9.4e-48 162.9 2.1 1.2e-47 162.5 1.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEQ28002.1 - 3.9e-06 27.0 0.4 0.00056 20.0 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ28002.1 - 5.8e-06 26.2 1.1 1.8e-05 24.6 0.8 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEQ28002.1 - 5.9e-06 26.1 0.3 0.014 15.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEQ28002.1 - 0.00091 19.1 0.1 0.0085 15.9 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEQ28002.1 - 0.0021 17.0 0.2 0.0035 16.3 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EEQ28002.1 - 0.0034 16.4 0.0 0.0064 15.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EEQ28002.1 - 0.035 12.9 6.7 0.082 11.7 4.6 1.5 1 1 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.1 EEQ28002.1 - 0.16 10.8 0.1 0.44 9.4 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF2884 PF11101.3 EEQ28003.1 - 0.037 13.4 2.2 0.059 12.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF972 PF06156.8 EEQ28003.1 - 0.59 10.5 3.3 1.2 9.4 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EEQ28003.1 - 5.7 6.4 7.9 11 5.4 5.4 1.4 1 1 0 1 1 1 0 IncA protein 2OG-FeII_Oxy_2 PF13532.1 EEQ28005.1 - 1.3e-12 47.9 0.0 4e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EEQ28005.1 - 8.3e-05 22.8 0.0 0.00016 21.9 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.11 EEQ28006.1 - 1.2e-08 34.8 0.6 1.2e-08 34.8 0.4 2.1 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ank_2 PF12796.2 EEQ28007.1 - 1.2e-27 96.0 0.3 2.3e-18 66.3 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ28007.1 - 3.1e-26 90.7 0.3 1.5e-10 40.9 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EEQ28007.1 - 8.9e-22 75.7 0.5 2e-07 30.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EEQ28007.1 - 7.2e-17 59.8 0.0 7.9e-06 25.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EEQ28007.1 - 1.7e-15 57.0 0.1 5.2e-08 33.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) His_Phos_1 PF00300.17 EEQ28008.1 - 5.9e-26 91.4 0.0 7.4e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L7Ae PF01248.21 EEQ28009.1 - 1.4e-26 91.8 0.6 1.7e-26 91.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EEQ28009.1 - 0.039 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Vac_ImportDeg PF09783.4 EEQ28010.1 - 1.9e-21 76.3 0.2 1.5e-20 73.4 0.0 2.1 2 0 0 2 2 2 1 Vacuolar import and degradation protein Lipid_bd PF12888.2 EEQ28010.1 - 0.14 11.9 0.4 0.25 11.1 0.3 1.3 1 0 0 1 1 1 0 Lipid-binding putative hydrolase MR_MLE_C PF13378.1 EEQ28011.1 - 8e-15 54.7 0.0 1.5e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like IU_nuc_hydro PF01156.14 EEQ28012.1 - 3.2e-73 246.6 0.0 4.5e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PXA PF02194.10 EEQ28013.1 - 7.5e-40 136.4 0.0 1.4e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 PXA domain HTH_Tnp_Tc5 PF03221.11 EEQ28015.1 - 1.3e-14 53.7 0.1 2.5e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EEQ28015.1 - 5.5e-06 25.7 0.0 1.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 EEQ28015.1 - 0.0016 18.0 0.1 0.0067 16.0 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain MarR PF01047.17 EEQ28015.1 - 0.0057 16.3 0.0 0.018 14.7 0.0 1.9 1 0 0 1 1 1 1 MarR family Sigma70_r4 PF04545.11 EEQ28015.1 - 0.0062 15.8 0.1 0.014 14.6 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.1 EEQ28015.1 - 0.03 13.8 0.1 0.077 12.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 EEQ28015.1 - 0.032 14.0 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.1 EEQ28015.1 - 0.051 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EEQ28015.1 - 0.074 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 MarR family TGS PF02824.16 EEQ28016.1 - 2.5e-22 78.4 0.0 5.1e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EEQ28016.1 - 7.1e-17 61.4 0.0 1.5e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ28016.1 - 9.5e-06 24.9 0.0 6.2e-05 22.3 0.0 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EEQ28016.1 - 0.00022 20.7 0.7 1.1 8.6 0.0 3.6 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EEQ28016.1 - 0.00036 20.3 0.2 0.061 13.1 0.0 2.4 1 1 0 2 2 2 2 Dynamin family ArgK PF03308.11 EEQ28016.1 - 0.007 15.1 0.3 0.02 13.7 0.1 1.8 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EEQ28016.1 - 0.047 14.1 0.0 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein CDO_I PF05995.7 EEQ28017.1 - 7.4e-41 139.2 0.0 8.8e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EEQ28017.1 - 2.8e-08 33.3 0.0 3.7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Cupin_7 PF12973.2 EEQ28017.1 - 0.018 14.8 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain TSSC4 PF15264.1 EEQ28017.1 - 0.097 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Glyco_transf_90 PF05686.7 EEQ28019.1 - 6.2e-14 51.4 10.7 3.1e-11 42.6 5.7 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_6 PF12697.2 EEQ28020.1 - 1.5e-20 74.0 0.0 3.1e-20 73.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ28020.1 - 4.8e-08 32.8 0.0 1.5e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ28020.1 - 2.1e-05 24.3 0.0 5.2e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EEQ28020.1 - 0.0073 16.2 0.6 0.019 14.8 0.4 1.8 1 1 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_2 PF02230.11 EEQ28020.1 - 0.0088 15.5 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EEQ28020.1 - 0.14 11.7 0.0 0.37 10.3 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein Glyco_transf_8 PF01501.15 EEQ28021.1 - 7.4e-36 123.7 0.0 1.3e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 HEAT PF02985.17 EEQ28022.1 - 5.4e-47 153.6 15.3 0.0029 17.5 0.1 13.0 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 EEQ28022.1 - 3.4e-35 120.2 0.4 1.5e-08 34.7 0.0 7.6 2 2 3 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 EEQ28022.1 - 3.7e-13 49.5 9.9 0.0024 18.2 0.0 9.9 7 3 4 11 11 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ28022.1 - 1.3e-11 44.7 3.4 0.00042 20.6 0.1 7.2 6 2 4 10 10 10 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EEQ28022.1 - 1.1e-08 33.9 6.0 2.4e-07 29.4 1.1 3.7 2 1 1 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.3 EEQ28022.1 - 0.0051 16.1 2.6 3.1 7.0 0.1 4.6 4 2 2 6 6 6 1 CLASP N terminal Arm PF00514.18 EEQ28022.1 - 0.0075 16.0 3.2 1.5 8.7 0.0 5.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 EEQ28022.1 - 0.013 14.5 0.6 0.073 12.0 0.2 2.3 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 EEQ28022.1 - 0.013 15.3 2.5 1.9 8.4 0.1 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2435) RIX1 PF08167.7 EEQ28022.1 - 0.076 12.6 0.1 4 7.0 0.0 3.4 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Trp_Tyr_perm PF03222.8 EEQ28022.1 - 0.16 10.7 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family B3_4 PF03483.12 EEQ28023.1 - 1.2e-24 86.7 0.1 2.2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EEQ28023.1 - 3.9e-17 61.8 0.0 1.7e-15 56.5 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 EEQ28023.1 - 0.059 12.5 0.0 0.43 9.7 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) HTH_33 PF13592.1 EEQ28023.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix DUF2740 PF10872.3 EEQ28023.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Ribosomal_S3_C PF00189.15 EEQ28024.1 - 1.1e-16 60.7 0.0 2.3e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EEQ28024.1 - 2.7e-12 46.0 0.1 4.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EEQ28024.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.9 EEQ28025.1 - 1.1e-123 412.5 0.0 1.4e-123 412.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EEQ28025.1 - 0.00051 20.3 0.4 0.0027 17.9 0.0 2.1 2 1 0 3 3 3 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EEQ28025.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SLS PF14611.1 EEQ28026.1 - 7e-55 185.7 0.1 1.2e-54 184.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Pkinase PF00069.20 EEQ28027.1 - 6.1e-30 104.2 0.0 7.5e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28027.1 - 5.7e-25 87.8 0.0 9.9e-25 87.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ28027.1 - 2.4e-05 23.5 0.1 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ28027.1 - 3.5e-05 22.9 0.0 5.6e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EEQ28027.1 - 0.00033 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family PIP49_C PF12260.3 EEQ28027.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Seadorna_VP7 PF07387.6 EEQ28027.1 - 0.0031 16.3 1.1 0.088 11.6 0.2 2.3 2 1 0 2 2 2 1 Seadornavirus VP7 YukC PF10140.4 EEQ28027.1 - 0.0033 16.0 0.0 0.0049 15.4 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EEQ28027.1 - 0.0047 16.6 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ28027.1 - 0.029 13.9 1.7 0.15 11.6 1.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase NT-C2 PF10358.4 EEQ28028.1 - 5.3e-29 100.5 0.0 7.6e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins CAF-1_p150 PF11600.3 EEQ28029.1 - 0.0065 15.8 15.5 0.0095 15.3 10.7 1.2 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3584 PF12128.3 EEQ28029.1 - 0.0077 13.6 8.3 0.0088 13.4 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Filament PF00038.16 EEQ28029.1 - 0.012 15.0 11.8 0.015 14.8 8.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein Oxysterol_BP PF01237.13 EEQ28029.1 - 0.035 12.5 6.1 0.041 12.3 4.2 1.0 1 0 0 1 1 1 0 Oxysterol-binding protein Atg14 PF10186.4 EEQ28029.1 - 0.053 12.4 10.8 0.066 12.1 7.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RolB_RolC PF02027.12 EEQ28029.1 - 0.15 11.2 0.7 0.19 10.8 0.5 1.1 1 0 0 1 1 1 0 RolB/RolC glucosidase family Dynamin_N PF00350.18 EEQ28029.1 - 0.16 11.8 1.9 0.19 11.5 1.3 1.2 1 0 0 1 1 1 0 Dynamin family Seryl_tRNA_N PF02403.17 EEQ28029.1 - 0.6 10.1 12.8 0.39 10.7 7.8 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cas_Csy4 PF09618.5 EEQ28029.1 - 2.2 8.0 7.2 3 7.6 5.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) IncA PF04156.9 EEQ28029.1 - 2.2 7.8 11.3 2.9 7.4 7.8 1.2 1 0 0 1 1 1 0 IncA protein Peptidase_S49_N PF08496.5 EEQ28029.1 - 2.7 7.7 9.8 4.3 7.1 6.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal APG6 PF04111.7 EEQ28029.1 - 5.1 6.0 13.7 6.6 5.6 9.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SF3b10 PF07189.6 EEQ28032.1 - 3.4e-35 119.7 0.0 3.8e-35 119.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) A_deamin PF02137.13 EEQ28034.1 - 3.4e-46 158.1 0.0 2.3e-45 155.4 0.0 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain ERG4_ERG24 PF01222.12 EEQ28035.1 - 9.4e-134 446.1 2.3 1.1e-133 445.8 1.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EEQ28035.1 - 0.00013 21.3 0.8 0.00034 19.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.10 EEQ28036.1 - 3e-09 36.2 0.1 4.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EEQ28036.1 - 1.3e-08 34.6 0.1 0.00018 21.2 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Herpes_LMP1 PF05297.6 EEQ28036.1 - 0.053 12.4 1.3 0.068 12.0 0.9 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ATG27 PF09451.5 EEQ28036.1 - 0.061 12.5 0.0 0.061 12.5 0.0 2.5 1 1 1 2 2 2 0 Autophagy-related protein 27 CDC45 PF02724.9 EEQ28036.1 - 0.062 11.3 4.1 0.081 10.9 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RNase_H2_suC PF08615.6 EEQ28036.1 - 0.066 13.0 0.5 0.19 11.5 0.5 1.5 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nop14 PF04147.7 EEQ28036.1 - 0.13 10.1 4.5 0.15 9.9 3.1 1.1 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.13 EEQ28037.1 - 9.5e-24 83.6 0.0 1.7e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ28037.1 - 2.4e-06 27.3 8.8 5.1e-06 26.3 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FimP PF09766.4 EEQ28037.1 - 0.42 9.6 12.9 0.86 8.6 8.9 1.4 1 0 0 1 1 1 0 Fms-interacting protein TFIIA PF03153.8 EEQ28037.1 - 3.3 7.5 33.8 0.45 10.3 8.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SKG6 PF08693.5 EEQ28038.1 - 9.3e-07 28.0 0.1 9.3e-07 28.0 0.1 2.0 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.8 EEQ28038.1 - 1.1 9.5 5.8 5 7.4 0.0 2.2 1 1 1 2 2 2 0 Alphavirus glycoprotein J Glyco_hydro_47 PF01532.15 EEQ28039.1 - 1.2e-171 571.3 0.0 1.4e-171 571.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EEQ28039.1 - 0.06 11.6 0.0 1.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_3 PF00933.16 EEQ28040.1 - 5e-93 311.3 0.0 7.5e-93 310.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEQ28040.1 - 9e-57 192.1 0.8 3.3e-56 190.3 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEQ28040.1 - 1.2e-12 47.5 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase PF00069.20 EEQ28042.1 - 1.4e-31 109.5 0.0 2.7e-31 108.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28042.1 - 0.0015 17.6 0.0 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase tRNA-synt_1e PF01406.14 EEQ28043.1 - 6.9e-21 74.6 0.2 3.5e-16 59.2 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain EBP PF05241.7 EEQ28044.1 - 0.00019 20.5 5.6 0.00055 18.9 3.9 1.8 1 1 0 1 1 1 1 Emopamil binding protein Zn_clus PF00172.13 EEQ28045.1 - 0.0051 16.6 12.3 0.01 15.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Scs3p PF10261.4 EEQ28046.1 - 1.2e-59 201.2 3.9 1.6e-59 200.8 2.7 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Erythro_esteras PF05139.9 EEQ28048.1 - 5.6e-139 463.1 0.6 6.6e-139 462.9 0.4 1.0 1 0 0 1 1 1 1 Erythromycin esterase DUF399 PF04187.8 EEQ28048.1 - 0.0012 18.3 0.4 0.63 9.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF399 Mannitol_dh PF01232.18 EEQ28048.1 - 0.16 11.9 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain HrpF PF06266.7 EEQ28048.1 - 0.19 11.8 0.7 0.4 10.8 0.5 1.5 1 0 0 1 1 1 0 HrpF protein DUF3629 PF12302.3 EEQ28049.1 - 0.00037 19.9 3.7 0.00037 19.9 2.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3629) DUF3535 PF12054.3 EEQ28050.1 - 4.6e-150 500.0 0.0 5.9e-149 496.4 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EEQ28050.1 - 1.7e-72 243.7 0.0 9e-72 241.3 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain HEAT PF02985.17 EEQ28050.1 - 1.3e-17 62.2 10.6 0.0051 16.7 0.1 10.0 11 0 0 11 11 11 4 HEAT repeat Helicase_C PF00271.26 EEQ28050.1 - 2.1e-14 53.1 0.0 6.4e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 EEQ28050.1 - 5.2e-06 26.7 0.2 0.13 12.6 0.0 4.1 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EEQ28050.1 - 5.4e-06 26.5 15.7 0.0066 16.7 0.1 8.1 6 2 2 8 8 8 1 HEAT repeats CLASP_N PF12348.3 EEQ28050.1 - 6.5e-05 22.3 0.0 0.021 14.1 0.0 3.7 3 1 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.1 EEQ28050.1 - 0.00014 22.2 12.8 1.5 9.4 0.0 8.3 9 0 0 9 9 9 1 HEAT-like repeat Sec39 PF08314.6 EEQ28051.1 - 5.1e-195 649.4 0.0 7.4e-195 648.9 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Pkinase PF00069.20 EEQ28052.1 - 2.9e-61 206.9 0.0 3.5e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28052.1 - 3.1e-35 121.4 0.0 4.3e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ28052.1 - 5.6e-09 35.3 0.0 8.4e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ28052.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CN_hydrolase PF00795.17 EEQ28053.1 - 7e-25 87.4 0.0 1.2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EEQ28053.1 - 1.8e-24 85.9 0.0 4.9e-24 84.5 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Protoglobin PF11563.3 EEQ28054.1 - 9.8e-42 142.2 0.0 1.3e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protoglobin DUF1499 PF07386.6 EEQ28054.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) AAA PF00004.24 EEQ28063.1 - 2.8e-18 66.3 0.0 5.8e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ28063.1 - 3.5e-06 27.1 0.2 2.9e-05 24.1 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EEQ28063.1 - 0.00036 20.6 0.1 0.0085 16.2 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EEQ28063.1 - 0.00096 18.8 0.0 0.0032 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EEQ28063.1 - 0.0034 17.6 0.0 0.0098 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ28063.1 - 0.0045 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ28063.1 - 0.0046 17.7 0.0 0.021 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ28063.1 - 0.005 16.5 0.3 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 EEQ28063.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 EEQ28063.1 - 0.039 13.9 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EEQ28063.1 - 0.063 12.3 0.0 1.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 EEQ28063.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EEQ28063.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EEQ28063.1 - 0.19 10.4 0.0 0.35 9.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PRY PF13765.1 EEQ28064.1 - 0.11 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 SPRY-associated domain Pkinase PF00069.20 EEQ28065.1 - 0.0002 20.5 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain AAA_35 PF14516.1 EEQ28065.1 - 0.21 10.2 0.0 0.39 9.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain PI3_PI4_kinase PF00454.22 EEQ28067.1 - 0.0046 16.4 0.1 0.0085 15.5 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase APH PF01636.18 EEQ28067.1 - 0.0091 15.7 0.1 3.6 7.2 0.0 2.5 2 1 0 2 2 2 2 Phosphotransferase enzyme family Aspzincin_M35 PF14521.1 EEQ28069.1 - 8.9e-05 23.0 0.0 0.00029 21.3 0.0 1.9 2 1 1 3 3 3 1 Lysine-specific metallo-endopeptidase TPR_11 PF13414.1 EEQ28070.1 - 1.5e-34 117.4 14.7 4.4e-17 61.4 0.2 5.7 4 2 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 EEQ28070.1 - 4.9e-29 97.8 4.8 9.6e-07 28.2 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ28070.1 - 2.3e-28 96.5 9.0 6e-07 28.7 0.1 7.1 7 1 1 8 8 8 4 Tetratricopeptide repeat DnaJ PF00226.26 EEQ28070.1 - 2.2e-27 94.5 3.8 4.3e-27 93.6 0.7 2.8 3 0 0 3 3 3 1 DnaJ domain TPR_16 PF13432.1 EEQ28070.1 - 1.5e-20 73.2 15.1 6.2e-06 26.7 0.6 5.4 5 1 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ28070.1 - 5.7e-20 71.4 6.8 0.0001 22.5 0.0 5.1 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ28070.1 - 3.5e-18 64.2 2.6 0.0031 17.5 0.0 6.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ28070.1 - 1.5e-17 62.5 18.0 0.00035 20.9 0.0 8.5 5 3 5 10 10 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ28070.1 - 1.8e-15 56.6 6.5 7.1e-05 22.6 0.2 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat Apc3 PF12895.2 EEQ28070.1 - 3.2e-15 56.0 0.3 1.5e-06 28.2 0.1 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EEQ28070.1 - 1.4e-14 52.6 7.3 0.0088 15.7 0.0 6.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ28070.1 - 4.3e-13 48.0 2.1 0.0037 16.9 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ28070.1 - 1.8e-10 40.4 3.8 0.0027 17.5 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ28070.1 - 4.3e-10 39.3 13.2 0.00016 21.9 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ28070.1 - 7e-06 25.2 1.3 0.078 12.0 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 EEQ28070.1 - 0.00053 20.3 2.4 0.24 11.6 0.4 3.6 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_20 PF14561.1 EEQ28070.1 - 0.0057 16.7 5.4 3.2 7.9 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ28070.1 - 0.01 15.7 9.8 1.5 8.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 EEQ28070.1 - 0.011 15.7 3.0 2.4 8.0 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ28070.1 - 0.058 13.8 15.4 0.37 11.3 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEQ28070.1 - 0.093 12.6 3.2 11 6.0 0.0 3.8 3 2 2 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 EEQ28070.1 - 0.28 11.0 3.6 2.5 8.0 0.0 3.8 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain DUF4451 PF14616.1 EEQ28071.1 - 1.5e-32 112.0 0.7 1.5e-32 112.0 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) APH PF01636.18 EEQ28072.1 - 6.7e-11 42.3 0.0 1.4e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ28072.1 - 0.00053 19.2 0.0 0.00095 18.3 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EEQ28072.1 - 0.0087 14.7 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EEQ28072.1 - 0.024 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box PF00646.28 EEQ28073.1 - 4.8e-06 26.0 5.1 5.4e-06 25.9 1.1 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EEQ28073.1 - 1.5e-05 24.6 0.5 4.8e-05 22.9 0.4 2.0 1 0 0 1 1 1 1 F-box-like Kdo PF06293.9 EEQ28074.1 - 9.9e-05 21.4 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ28074.1 - 0.00036 20.3 0.5 0.00056 19.7 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ28074.1 - 0.0053 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EEQ28074.1 - 0.0072 15.9 0.1 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ28074.1 - 0.025 13.7 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.6 EEQ28074.1 - 0.028 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.1 EEQ28074.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EEQ28075.1 - 3.3e-16 59.7 0.0 6.3e-16 58.8 0.0 1.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ28075.1 - 2.6e-05 23.5 0.0 0.021 13.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.15 EEQ28075.1 - 8.1e-05 22.2 0.2 0.0017 17.9 0.2 2.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EEQ28075.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Sugar_tr PF00083.19 EEQ28076.1 - 3.1e-82 276.5 29.2 3.6e-82 276.3 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ28076.1 - 1.4e-14 53.5 36.4 5.5e-11 41.7 10.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EEQ28076.1 - 0.0012 18.7 3.5 0.17 11.9 0.3 3.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1228) DUF4098 PF13345.1 EEQ28077.1 - 0.17 11.8 4.0 9.8 6.2 0.4 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF4098) ERM PF00769.14 EEQ28078.1 - 0.97 8.9 39.9 1.4 8.3 27.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Pkinase PF00069.20 EEQ28079.1 - 9.7e-39 133.0 0.0 1.5e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28079.1 - 7.5e-27 94.0 0.0 1.1e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ28079.1 - 0.00022 20.2 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ28079.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.17 EEQ28080.1 - 2.9e-55 186.0 0.0 3.7e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ28080.1 - 3.4e-20 72.7 0.0 4.8e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ28080.1 - 3.7e-13 49.0 0.0 6.1e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ28080.1 - 8.2e-06 25.1 0.0 9.4e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEQ28080.1 - 4.9e-05 22.8 0.0 0.00013 21.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ28080.1 - 0.00021 21.1 0.0 0.00053 19.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EEQ28080.1 - 0.016 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Acetate_kinase PF00871.12 EEQ28084.1 - 2.7e-89 299.4 0.2 3.2e-89 299.2 0.1 1.0 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.5 EEQ28085.1 - 2.8e-153 509.9 0.0 3.8e-153 509.5 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EEQ28085.1 - 2.1e-67 226.5 0.0 3.3e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EEQ28085.1 - 1.2e-54 184.6 0.1 1.2e-33 116.2 0.0 2.3 1 1 1 2 2 2 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Ribosomal_S7e PF01251.13 EEQ28086.1 - 7e-80 266.9 0.2 7.7e-80 266.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.8 EEQ28087.1 - 3.3e-178 593.3 0.2 3.9e-178 593.1 0.1 1.0 1 0 0 1 1 1 1 Dynactin p62 family Methyltransf_11 PF08241.7 EEQ28088.1 - 4.1e-09 36.7 0.0 8.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ28088.1 - 2.2e-08 33.9 0.0 3.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ28088.1 - 3.2e-06 27.5 0.0 6.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ28088.1 - 4.6e-06 26.2 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ28088.1 - 0.00067 18.8 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EEQ28088.1 - 0.085 13.4 0.0 0.37 11.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain P16-Arc PF04699.9 EEQ28089.1 - 6.1e-59 198.3 0.0 7.4e-59 198.1 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) E1-E2_ATPase PF00122.15 EEQ28090.1 - 1.4e-54 184.5 0.1 3.4e-54 183.2 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ28090.1 - 1.1e-45 155.4 11.5 1.1e-45 155.4 8.0 2.3 3 1 1 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ28090.1 - 7.5e-21 75.5 0.0 1.8e-20 74.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ28090.1 - 8.5e-17 60.9 0.0 1.6e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ28090.1 - 2.7e-09 37.4 0.0 7.1e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ28090.1 - 1.3e-08 34.1 0.1 7.1e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEQ28090.1 - 0.0003 20.4 0.1 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EEQ28090.1 - 0.031 14.1 0.1 0.031 14.1 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3325) SF3b1 PF08920.5 EEQ28090.1 - 0.075 13.0 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 GFO_IDH_MocA PF01408.17 EEQ28092.1 - 7e-08 33.0 0.3 2.3e-07 31.3 0.2 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.17 EEQ28093.1 - 9.5e-34 116.3 0.0 7.5e-33 113.3 0.0 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family WD40 PF00400.27 EEQ28094.1 - 8.5e-42 139.5 7.3 1e-09 37.8 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.2 EEQ28094.1 - 2.2e-06 27.2 0.2 4.3e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.1 EEQ28094.1 - 0.00016 21.2 0.7 0.004 16.6 0.2 2.6 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.16 EEQ28094.1 - 0.0002 20.7 0.1 3.4 7.3 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat Nup160 PF11715.3 EEQ28094.1 - 0.04 12.0 0.3 2.3 6.2 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 F-box PF00646.28 EEQ28094.1 - 0.067 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 F-box domain ADH_zinc_N_2 PF13602.1 EEQ28095.1 - 7.9e-13 49.4 0.0 1.3e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEQ28095.1 - 2.7e-09 36.6 0.0 4.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EB1 PF03271.12 EEQ28097.1 - 1.6e-17 63.2 0.7 2.8e-17 62.4 0.5 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EEQ28097.1 - 4.7e-08 33.0 0.6 8e-08 32.2 0.4 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 EEQ28097.1 - 0.011 13.9 0.0 0.016 13.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Syndecan PF01034.15 EEQ28099.1 - 0.5 10.0 1.2 1.1 8.9 0.8 1.5 1 0 0 1 1 1 0 Syndecan domain Glutaredoxin PF00462.19 EEQ28102.1 - 1.5e-19 69.7 0.0 2.1e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 EEQ28102.1 - 0.025 14.8 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.1 EEQ28102.1 - 0.037 13.5 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.15 EEQ28102.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Chalcone PF02431.10 EEQ28103.1 - 4.2e-62 209.0 0.0 5.4e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase GTP_EFTU PF00009.22 EEQ28104.1 - 8.8e-57 191.5 0.0 1.5e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEQ28104.1 - 7.4e-37 125.5 0.1 2e-36 124.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEQ28104.1 - 1.2e-16 60.5 2.2 3.9e-16 58.9 1.5 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EEQ28104.1 - 3.1e-05 23.5 0.6 0.00011 21.7 0.5 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EEQ28104.1 - 0.0039 17.1 0.1 0.011 15.6 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIS_C PF01096.13 EEQ28105.1 - 2.5e-19 68.5 2.0 2.5e-19 68.5 1.4 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEQ28105.1 - 2e-05 24.1 7.1 3.7e-05 23.3 2.1 3.0 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EEQ28105.1 - 0.0081 15.9 5.6 0.26 11.1 0.5 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain IBR PF01485.16 EEQ28105.1 - 0.092 12.6 7.3 1.8 8.5 0.2 2.8 2 1 0 2 2 2 0 IBR domain Zn_ribbon_recom PF13408.1 EEQ28105.1 - 0.13 12.5 3.0 0.57 10.4 0.5 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain C1_4 PF07975.7 EEQ28105.1 - 0.14 12.1 4.1 1.7 8.7 0.1 2.7 2 2 0 2 2 2 0 TFIIH C1-like domain DZR PF12773.2 EEQ28105.1 - 0.21 11.4 6.1 0.31 10.8 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon Baculo_LEF5_C PF11792.3 EEQ28105.1 - 0.38 10.1 0.0 0.38 10.1 0.0 1.9 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-Mss51 PF13824.1 EEQ28105.1 - 0.44 10.4 3.4 1.5 8.7 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 NOB1_Zn_bind PF08772.6 EEQ28105.1 - 0.46 10.3 3.3 0.26 11.1 0.4 2.1 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Rubredoxin PF00301.15 EEQ28105.1 - 0.64 9.9 9.0 4.6 7.2 0.3 3.4 3 0 0 3 3 3 0 Rubredoxin TF_Zn_Ribbon PF08271.7 EEQ28105.1 - 0.64 9.3 4.9 3.8 6.9 0.1 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 EEQ28105.1 - 1.3 8.7 13.6 3.4 7.4 0.5 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EEQ28105.1 - 1.7 8.2 13.0 3 7.4 0.4 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 EEQ28105.1 - 2.6 7.6 7.4 0.48 9.9 1.1 2.7 2 1 0 2 2 2 0 InsA N-terminal domain zinc_ribbon_2 PF13240.1 EEQ28105.1 - 3.8 7.1 8.7 5.4 6.6 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain GFA PF04828.9 EEQ28105.1 - 3.8 7.5 7.5 10 6.1 0.1 3.0 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-H2C2_2 PF13465.1 EEQ28105.1 - 4.2 7.8 11.7 5.3 7.5 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger double domain FdhE PF04216.7 EEQ28105.1 - 5.8 6.5 7.6 14 5.2 0.9 2.1 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation Nudix_N_2 PF14803.1 EEQ28105.1 - 6.9 6.4 8.6 29 4.4 2.5 3.1 2 1 0 2 2 2 0 Nudix N-terminal NAD_binding_10 PF13460.1 EEQ28106.1 - 4.3e-06 26.8 0.0 6.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEQ28106.1 - 1.3e-05 24.5 0.0 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.12 EEQ28106.1 - 0.072 13.5 0.0 2.5 8.5 0.0 2.6 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AMP-binding PF00501.23 EEQ28107.1 - 8.8e-95 317.5 0.0 1.6e-94 316.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EEQ28107.1 - 5.9e-77 258.5 0.2 8.9e-76 254.7 0.2 2.2 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ28107.1 - 1.7e-67 227.9 0.1 2.9e-67 227.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EEQ28107.1 - 6.2e-57 192.1 0.0 2.8e-56 190.0 0.1 2.1 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EEQ28107.1 - 2.8e-50 170.5 0.0 9.2e-49 165.5 0.1 2.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EEQ28107.1 - 4.7e-46 156.7 0.0 1.4e-44 151.9 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EEQ28107.1 - 4.1e-41 139.5 0.4 9.8e-41 138.3 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EEQ28107.1 - 4.2e-21 74.9 2.2 5.6e-12 45.7 0.0 4.1 4 0 0 4 4 4 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ28107.1 - 9.5e-11 42.5 0.0 3.4e-10 40.7 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EEQ28107.1 - 1.1e-10 41.3 0.0 7e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ28107.1 - 2.7e-06 26.3 0.0 0.0027 16.4 0.0 2.6 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EEQ28107.1 - 2.1e-05 23.5 0.0 0.014 14.2 0.0 2.8 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 EEQ28107.1 - 0.00016 20.7 0.0 0.00032 19.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.1 EEQ28107.1 - 0.0019 18.2 0.0 0.48 10.4 0.0 2.8 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EEQ28107.1 - 0.002 17.4 0.3 0.47 9.6 0.0 2.5 2 0 0 2 2 2 1 NmrA-like family ACP_syn_III PF08545.5 EEQ28107.1 - 0.028 14.0 1.3 0.099 12.3 0.9 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PTS-HPr PF00381.14 EEQ28107.1 - 0.052 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 PTS HPr component phosphorylation site Ribosomal_L30 PF00327.15 EEQ28107.1 - 0.14 11.7 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e PhyH PF05721.8 EEQ28108.1 - 1.4e-16 61.1 0.0 2.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_1_2 PF00155.16 EEQ28109.1 - 1.6e-18 66.7 0.0 2.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ28109.1 - 0.0092 14.7 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ28109.1 - 0.058 12.4 0.1 0.89 8.5 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family NmrA PF05368.8 EEQ28110.1 - 2.3e-14 53.2 0.0 3.6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ28110.1 - 6.7e-10 39.2 0.5 2.1e-09 37.6 0.4 1.9 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EEQ28110.1 - 6.2e-05 22.7 0.5 9.5e-05 22.1 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ28110.1 - 0.00012 21.6 0.1 0.00031 20.2 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEQ28110.1 - 0.00089 19.2 2.1 0.0014 18.5 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EEQ28110.1 - 0.0026 16.7 0.5 0.0035 16.3 0.3 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase CbiJ PF02571.9 EEQ28110.1 - 0.024 13.9 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Shikimate_DH PF01488.15 EEQ28110.1 - 0.049 13.7 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 EEQ28110.1 - 0.078 11.8 0.4 0.12 11.2 0.3 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain AA_permease_2 PF13520.1 EEQ28111.1 - 2.3e-34 118.6 51.1 2.8e-34 118.4 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ28111.1 - 4.7e-07 28.5 44.0 8.8e-07 27.6 30.5 1.4 1 1 0 1 1 1 1 Amino acid permease DUF3671 PF12420.3 EEQ28111.1 - 6.3 6.8 7.6 12 5.9 1.9 3.0 3 1 0 3 3 3 0 Protein of unknown function PhyH PF05721.8 EEQ28112.1 - 2.4e-22 79.9 0.0 3.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EEQ28112.1 - 0.039 12.4 0.0 0.055 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Ank PF00023.25 EEQ28113.1 - 4e-11 42.1 0.2 7.7e-08 31.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EEQ28113.1 - 6e-09 36.1 0.0 0.023 15.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ28113.1 - 1.3e-07 31.1 0.3 2.7e-05 23.9 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.2 EEQ28113.1 - 3.5e-07 30.4 0.0 0.00022 21.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ28113.1 - 2.9e-06 27.3 0.2 0.49 10.7 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) MAGE PF01454.14 EEQ28114.1 - 5e-42 143.4 0.0 6.5e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 MAGE family DUF1147 PF06615.6 EEQ28114.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) APH PF01636.18 EEQ28115.1 - 3e-13 50.0 0.0 1.2e-12 48.1 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ28115.1 - 0.12 11.0 0.0 1.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) ATP-grasp_4 PF13535.1 EEQ28116.1 - 1.2e-19 70.7 0.0 1.8e-18 66.9 0.0 2.6 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEQ28116.1 - 9.8e-08 31.6 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EEQ28116.1 - 0.00012 21.3 0.0 0.00034 19.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EEQ28116.1 - 0.00018 21.3 0.0 0.00066 19.5 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEQ28116.1 - 0.00059 18.6 0.0 0.0016 17.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.14 EEQ28116.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_TupA PF14305.1 EEQ28116.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 TupA-like ATPgrasp Pal1 PF08316.6 EEQ28117.1 - 3.6e-49 166.8 1.1 9.1e-49 165.5 0.7 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein Med31 PF05669.7 EEQ28119.1 - 4.7e-25 87.2 0.1 1.2e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 SOH1 PHD PF00628.24 EEQ28121.1 - 1.4e-10 40.6 8.1 1.4e-10 40.6 5.6 2.2 2 0 0 2 2 2 1 PHD-finger Choline_kinase PF01633.15 EEQ28121.1 - 0.091 12.3 0.7 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Fungal_trans PF04082.13 EEQ28123.1 - 2.7e-31 108.3 0.0 4.8e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ28123.1 - 5e-11 42.3 13.4 1.1e-10 41.2 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EEQ28123.1 - 0.16 11.8 0.1 0.53 10.2 0.1 1.8 1 0 0 1 1 1 0 Gal4-like dimerisation domain zf-C2H2 PF00096.21 EEQ28124.1 - 9.4e-06 25.6 18.8 3.3e-05 23.9 1.9 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ28124.1 - 2.2e-05 24.5 3.3 2.2e-05 24.5 2.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EEQ28124.1 - 0.00084 19.4 0.7 0.0039 17.3 0.5 2.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EEQ28124.1 - 0.0017 18.5 0.7 0.0017 18.5 0.5 3.6 4 0 0 4 4 4 1 C2H2-type zinc finger Fork_head PF00250.13 EEQ28125.1 - 2.3e-36 123.6 2.5 5.2e-36 122.5 1.7 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EEQ28125.1 - 1.1e-09 38.2 0.0 9.6e-09 35.2 0.0 2.4 2 0 0 2 2 2 1 FHA domain Protocadherin PF08374.6 EEQ28127.1 - 0.069 12.7 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 Protocadherin Ribosomal_L24e PF01246.15 EEQ28128.1 - 4.1e-28 97.0 2.1 9.3e-28 95.9 1.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DnaJ PF00226.26 EEQ28129.1 - 4.4e-07 29.5 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EEQ28129.1 - 1.9e-06 27.6 0.2 4.1e-06 26.5 0.2 1.6 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EEQ28129.1 - 0.008 15.4 0.9 0.008 15.4 0.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) Pkinase PF00069.20 EEQ28130.1 - 8.2e-69 231.6 0.0 1e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28130.1 - 3.1e-30 105.1 0.0 4.5e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ28130.1 - 0.07 12.8 0.1 0.07 12.8 0.1 2.6 2 2 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EEQ28130.1 - 0.088 11.8 0.0 0.25 10.3 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family G_glu_transpept PF01019.16 EEQ28131.1 - 1.2e-136 456.2 0.0 1.4e-136 456.0 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase p450 PF00067.17 EEQ28132.1 - 1.9e-25 89.3 0.0 3.1e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Clusterin PF01093.12 EEQ28133.1 - 0.7 8.6 3.9 1.1 7.9 2.7 1.2 1 0 0 1 1 1 0 Clusterin ICL PF00463.16 EEQ28135.1 - 4.1e-286 949.2 0.7 4.6e-286 949.0 0.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EEQ28135.1 - 4.5e-12 45.6 0.0 9.2e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.13 EEQ28137.1 - 1.6e-193 644.0 0.0 1.9e-193 643.8 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EEQ28137.1 - 3.5e-17 61.4 0.1 5.6e-17 60.7 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF4024 PF13216.1 EEQ28137.1 - 0.03 14.1 0.3 0.055 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) RHH_4 PF13467.1 EEQ28137.1 - 0.095 12.6 0.0 5 7.0 0.0 2.8 3 0 0 3 3 3 0 Ribbon-helix-helix domain adh_short_C2 PF13561.1 EEQ28138.1 - 1.1e-26 94.1 0.0 1.3e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ28138.1 - 3.4e-26 92.1 0.0 4.9e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ28138.1 - 1.6e-07 31.1 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 KR domain OTU PF02338.14 EEQ28139.1 - 4.8e-16 59.4 0.2 2.7e-15 57.0 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EEQ28139.1 - 8.4e-06 25.3 0.1 0.01 15.1 0.0 2.6 3 0 0 3 3 3 2 Peptidase C65 Otubain Cep57_MT_bd PF06657.8 EEQ28139.1 - 0.49 10.3 4.4 1.1 9.2 3.1 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 OmpH PF03938.9 EEQ28139.1 - 5.1 7.0 11.3 2.8 7.8 2.7 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TPMT PF05724.6 EEQ28140.1 - 1.7e-26 93.0 0.0 8.2e-26 90.7 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EEQ28140.1 - 0.00025 20.6 0.0 0.00077 19.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ28140.1 - 0.0005 20.0 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ28140.1 - 0.00067 20.1 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ28140.1 - 0.0039 17.5 0.0 0.0062 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.7 EEQ28140.1 - 0.014 14.3 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein AdoMet_MTase PF07757.8 EEQ28140.1 - 0.084 13.0 0.1 0.19 11.8 0.1 1.5 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MFS_1 PF07690.11 EEQ28141.1 - 8.2e-51 172.7 67.0 2.6e-43 148.1 28.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ28141.1 - 2.9e-07 29.4 33.6 7.5e-07 28.0 10.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EEQ28141.1 - 0.54 8.2 13.3 0.85 7.5 0.2 3.4 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.20 EEQ28143.1 - 5.5e-20 71.6 0.0 1e-19 70.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28143.1 - 0.0048 16.0 0.0 0.032 13.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Fer4_2 PF12797.2 EEQ28145.1 - 0.15 12.0 0.2 0.15 12.0 0.1 1.9 3 0 0 3 3 3 0 4Fe-4S binding domain Aldedh PF00171.17 EEQ28147.1 - 3.1e-84 282.9 0.0 3.9e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adap_comp_sub PF00928.16 EEQ28148.1 - 4.9e-52 176.6 0.0 7.2e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEQ28148.1 - 0.00048 19.8 0.0 0.00079 19.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4588 PF15251.1 EEQ28149.1 - 0.00048 20.1 11.4 0.0022 18.0 7.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.18 EEQ28150.1 - 3.3e-81 272.3 0.3 5.5e-81 271.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EEQ28150.1 - 8.2e-45 151.3 1.3 8.2e-45 151.3 0.9 2.4 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EEQ28150.1 - 5.5e-28 97.6 3.9 5.5e-28 97.6 2.7 4.6 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 EEQ28150.1 - 1.2e-14 53.8 0.0 3.8e-14 52.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ28150.1 - 1.2e-08 35.0 0.1 2.8e-07 30.5 0.0 3.5 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ28150.1 - 4.5e-06 26.2 0.0 1.3e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EEQ28150.1 - 0.012 15.4 0.4 0.072 12.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.10 EEQ28150.1 - 0.019 14.3 0.1 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 SpoU_methylase PF00588.14 EEQ28151.1 - 4.1e-24 85.0 0.0 8.3e-24 84.0 0.0 1.5 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EEQ28151.1 - 0.0011 19.1 0.0 0.0025 17.9 0.0 1.7 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 EEQ28152.1 - 1.1e-68 229.9 11.0 2.5e-68 228.7 7.6 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EEQ28152.1 - 3.9e-34 117.8 5.5 6.7e-18 64.5 0.2 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ28152.1 - 9.9e-14 50.9 0.1 3.1e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EEQ28152.1 - 2.1e-09 36.6 3.0 7.3e-09 34.8 2.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EEQ28152.1 - 2.4e-07 30.3 1.9 0.0077 15.8 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EEQ28152.1 - 0.00015 21.3 3.7 0.00015 21.3 2.6 3.8 2 2 0 2 2 2 1 PHD-finger ResIII PF04851.10 EEQ28152.1 - 0.035 13.9 1.0 0.18 11.6 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit SnAC PF14619.1 EEQ28152.1 - 0.33 11.1 6.0 0.098 12.8 1.1 2.5 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex MRP-S28 PF10213.4 EEQ28154.1 - 2.3e-39 134.3 0.0 4e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein XH PF03469.9 EEQ28154.1 - 0.067 12.8 0.2 9.3 5.9 0.0 2.7 3 0 0 3 3 3 0 XH domain SPT2 PF08243.6 EEQ28154.1 - 0.15 12.4 7.2 0.12 12.6 2.8 2.1 2 0 0 2 2 2 0 SPT2 chromatin protein Glyco_tran_28_C PF04101.11 EEQ28155.1 - 1.4e-18 67.1 0.2 7.8e-18 64.6 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EEQ28155.1 - 0.0044 16.2 0.1 0.0072 15.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 Actin PF00022.14 EEQ28156.1 - 7.8e-131 436.1 0.0 8.8e-131 435.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEQ28156.1 - 0.12 10.9 0.0 5.1 5.5 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein DUF3602 PF12223.3 EEQ28157.1 - 4.3e-17 62.2 1.3 1.5e-10 41.3 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 EEQ28157.1 - 0.26 10.9 1.7 19 4.9 0.2 2.9 2 1 1 3 3 3 0 GTP1/OBG HsbA PF12296.3 EEQ28160.1 - 7.8e-18 64.5 0.0 1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Ribosomal_S5_C PF03719.10 EEQ28160.1 - 0.027 13.7 0.1 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain PAH PF02671.16 EEQ28160.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat PsbK PF02533.10 EEQ28160.1 - 0.17 11.8 0.6 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Photosystem II 4 kDa reaction centre component p450 PF00067.17 EEQ28161.1 - 2.9e-54 184.3 0.0 3.6e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRP PF06011.7 EEQ28163.1 - 1.5e-137 458.7 32.2 9.6e-136 452.8 22.3 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEQ28163.1 - 2.2e-36 124.9 0.1 3.6e-36 124.3 0.1 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EEQ28163.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 ML domain IncA PF04156.9 EEQ28163.1 - 5 6.6 8.3 1.8 8.1 0.0 3.3 3 0 0 3 3 3 0 IncA protein APH PF01636.18 EEQ28167.1 - 5.1e-13 49.3 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ28167.1 - 0.0018 17.4 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EEQ28167.1 - 0.048 13.2 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ28167.1 - 0.05 12.2 0.0 0.088 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Hydrolase PF00702.21 EEQ28168.1 - 8.7e-13 49.1 0.0 1.2e-11 45.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEQ28168.1 - 9.8e-13 48.6 0.1 1.8e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ28168.1 - 8.6e-09 34.9 0.1 1.4e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EEQ28168.1 - 2.9e-06 27.5 0.0 4.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EEQ28168.1 - 0.058 13.2 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase zf-ribbon_3 PF13248.1 EEQ28169.1 - 0.076 12.2 7.4 0.074 12.2 0.9 3.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 EEQ28169.1 - 5.8 6.7 10.6 1.2 8.9 1.5 2.8 2 0 0 2 2 2 0 Zinc-ribbon ORMDL PF04061.9 EEQ28170.1 - 2.1e-61 205.4 4.1 2.4e-61 205.2 2.9 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 EEQ28170.1 - 0.46 10.1 4.6 0.41 10.2 0.9 1.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) PGA2 PF07543.7 EEQ28171.1 - 0.2 11.4 3.1 0.31 10.8 1.0 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 CH PF00307.26 EEQ28172.1 - 2.1e-10 40.5 0.0 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EEQ28172.1 - 0.19 11.4 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain NDUFA12 PF05071.11 EEQ28173.1 - 1.1e-12 48.3 0.8 1.1e-12 48.3 0.6 2.1 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Daxx PF03344.10 EEQ28175.1 - 0.019 13.4 14.6 0.023 13.2 10.1 1.2 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 EEQ28175.1 - 0.033 13.9 10.8 0.055 13.1 7.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Spore_coat_CotO PF14153.1 EEQ28175.1 - 0.25 10.7 1.9 0.39 10.1 1.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RRN3 PF05327.6 EEQ28175.1 - 0.83 7.6 7.5 1.2 7.1 5.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.9 EEQ28175.1 - 1.2 8.5 8.0 2.4 7.6 5.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 EEQ28175.1 - 1.9 6.4 12.8 2.9 5.8 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EEQ28175.1 - 5.1 4.8 26.6 8.2 4.2 18.4 1.3 1 0 0 1 1 1 0 Nop14-like family EMP24_GP25L PF01105.19 EEQ28179.1 - 1.6e-40 138.7 0.0 1.8e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RE_SacI PF09566.5 EEQ28179.1 - 0.071 12.0 0.1 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 SacI restriction endonuclease Sdh5 PF03937.11 EEQ28180.1 - 3.1e-23 81.2 0.2 6.6e-23 80.1 0.1 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase WD40 PF00400.27 EEQ28181.1 - 3e-60 198.0 27.4 9.5e-12 44.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEQ28181.1 - 0.00019 19.7 8.6 0.54 8.3 0.3 4.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EEQ28181.1 - 0.0059 14.9 0.0 0.51 8.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EEQ28181.1 - 0.046 13.4 0.1 41 3.9 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TPR_12 PF13424.1 EEQ28182.1 - 3.6e-10 39.6 11.4 0.0046 16.8 0.3 5.2 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ28182.1 - 7.7e-06 25.2 6.5 0.13 11.9 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ28182.1 - 0.00086 19.0 10.7 0.15 12.0 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ28182.1 - 0.0011 18.5 7.6 2.2 8.0 0.1 4.4 4 1 0 4 4 4 3 TPR repeat TPR_8 PF13181.1 EEQ28182.1 - 0.0049 16.5 12.6 2.7 7.9 0.0 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ28182.1 - 0.026 15.1 7.8 46 5.0 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF627 PF04781.7 EEQ28182.1 - 0.035 13.7 0.1 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_7 PF13176.1 EEQ28182.1 - 0.056 13.2 13.6 4.6 7.2 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ28182.1 - 0.094 13.2 9.3 11 6.7 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ28182.1 - 0.25 12.0 8.2 0.94 10.2 0.1 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 EEQ28182.1 - 0.6 10.8 5.0 39 5.0 0.1 4.2 4 0 0 4 4 4 0 Sel1 repeat TPR_19 PF14559.1 EEQ28182.1 - 1 9.7 5.1 1.9 8.9 0.1 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF159 PF02586.9 EEQ28183.1 - 1.5e-57 194.5 0.0 2e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 MAAL_C PF07476.6 EEQ28183.1 - 0.096 11.6 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Med1 PF10744.4 EEQ28185.1 - 1.8e-59 201.5 0.0 2.5e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Gln-synt_C PF00120.19 EEQ28186.1 - 1.1e-59 201.7 0.0 1.3e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EEQ28186.1 - 3.3e-20 71.4 0.0 5.5e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.11 EEQ28187.1 - 2.1e-28 99.0 39.2 2.1e-28 99.0 27.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEQ28187.1 - 0.0038 16.7 3.7 0.0097 15.4 2.5 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 AMP-binding PF00501.23 EEQ28188.1 - 8.5e-48 162.7 0.0 1.3e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ28188.1 - 0.012 16.5 0.0 0.039 14.8 0.0 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 EEQ28189.1 - 9e-101 337.6 22.8 1.1e-100 337.3 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ28189.1 - 2.2e-17 62.8 37.6 3.5e-14 52.2 5.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily zf-CCHC PF00098.18 EEQ28190.1 - 1.7e-48 160.3 92.6 1.2e-07 31.2 1.5 12.2 12 0 0 12 12 12 10 Zinc knuckle zf-CCHC_4 PF14392.1 EEQ28190.1 - 4.3e-08 32.6 66.0 0.16 11.6 0.6 10.4 10 0 0 10 10 10 9 Zinc knuckle zf-CCHC_3 PF13917.1 EEQ28190.1 - 3.2e-07 29.9 68.4 0.019 14.6 0.6 9.9 3 2 7 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.1 EEQ28190.1 - 0.032 13.7 45.5 0.12 11.9 0.4 10.2 8 3 3 11 11 11 0 Zinc knuckle DUF1700 PF08006.6 EEQ28191.1 - 1.5 8.1 4.0 2.1 7.6 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Pkinase PF00069.20 EEQ28192.1 - 1.3e-27 96.5 0.0 2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28192.1 - 0.0001 21.5 0.1 0.036 13.1 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ28192.1 - 0.023 13.5 0.3 0.032 13.0 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Saf-Nte_pilin PF09460.5 EEQ28193.1 - 0.12 12.1 0.0 1.5 8.5 0.0 2.0 2 0 0 2 2 2 0 Saf-pilin pilus formation protein DUF846 PF05832.7 EEQ28194.1 - 1.3e-44 151.3 7.5 1.6e-44 151.0 5.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Acyl-CoA_dh_1 PF00441.19 EEQ28195.1 - 4.6e-31 107.9 0.1 6.3e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ28195.1 - 4.8e-20 70.8 0.9 4.4e-19 67.7 0.4 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEQ28195.1 - 7.2e-19 68.4 0.0 1.1e-17 64.5 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEQ28195.1 - 0.0015 18.7 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ECH PF00378.15 EEQ28196.1 - 5.6e-30 104.2 0.2 1.8e-26 92.7 0.2 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family HpcH_HpaI PF03328.9 EEQ28197.1 - 3.4e-42 143.8 0.0 4.6e-41 140.1 0.0 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EEQ28197.1 - 2.7e-14 52.7 0.0 5.7e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Smr PF01713.16 EEQ28198.1 - 1.4e-11 44.4 0.1 4.1e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 EEQ28198.1 - 5.7e-08 32.6 2.7 1.5e-07 31.2 1.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 EEQ28198.1 - 2.4e-07 30.2 1.0 0.0026 17.4 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 EEQ28198.1 - 0.11 12.6 0.3 0.59 10.2 0.0 2.2 2 0 0 2 2 2 0 HBS1 N-terminus Glyco_transf_90 PF05686.7 EEQ28199.1 - 2e-13 49.8 3.9 2.2e-11 43.0 1.4 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 CAP59_mtransfer PF11735.3 EEQ28200.1 - 5.3e-82 274.6 0.0 7.4e-82 274.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 LTP_2 PF14368.1 EEQ28201.1 - 0.0095 16.0 5.6 0.017 15.2 4.0 1.3 1 1 0 1 1 1 1 Probable lipid transfer Tetraspannin PF00335.15 EEQ28201.1 - 0.016 14.4 2.3 0.018 14.3 1.6 1.0 1 0 0 1 1 1 0 Tetraspanin family UCR_hinge PF02320.11 EEQ28201.1 - 0.097 12.6 0.7 0.15 12.0 0.1 1.6 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Toxin_5 PF05294.8 EEQ28201.1 - 4.9 7.4 10.2 1.6 8.9 0.3 2.4 2 0 0 2 2 2 0 Scorpion short toxin DUF346 PF03984.8 EEQ28202.1 - 1.1e-19 69.6 57.9 0.00077 18.8 1.3 7.2 7 0 0 7 7 7 6 Repeat of unknown function (DUF346) Toxin_42 PF15522.1 EEQ28202.1 - 0.00016 20.9 0.0 34 3.5 0.0 5.7 7 0 0 7 7 7 1 Putative toxin 42 DUF1724 PF08350.5 EEQ28202.1 - 0.0031 16.9 7.7 0.47 10.0 0.0 4.8 5 0 0 5 5 5 2 Domain of unknown function (DUF1724) DUF2510 PF10708.4 EEQ28202.1 - 0.17 11.3 52.4 0.34 10.3 2.7 6.4 6 0 0 6 6 6 0 Protein of unknown function (DUF2510) Pkinase PF00069.20 EEQ28203.1 - 1.2e-13 50.8 0.0 3e-08 33.1 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain SNARE_assoc PF09335.6 EEQ28204.1 - 7.9e-06 26.0 9.4 7.9e-06 26.0 6.5 3.5 2 1 1 3 3 3 1 SNARE associated Golgi protein HAMP PF00672.20 EEQ28204.1 - 0.25 11.5 2.7 0.48 10.6 0.0 2.7 3 0 0 3 3 3 0 HAMP domain NfeD PF01957.13 EEQ28204.1 - 2.4 8.2 0.0 2.4 8.2 0.0 3.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Amino_oxidase PF01593.19 EEQ28205.1 - 1.9e-91 307.4 0.0 4.3e-91 306.2 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EEQ28205.1 - 1.2e-10 41.3 0.0 2.6e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EEQ28205.1 - 3.5e-08 33.3 0.0 7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EEQ28205.1 - 2.1e-05 24.6 1.1 0.00026 21.1 0.7 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box DAO PF01266.19 EEQ28205.1 - 0.00013 20.9 0.0 0.015 14.1 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEQ28205.1 - 0.003 17.6 0.0 0.032 14.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ28205.1 - 0.012 15.3 0.3 0.89 9.3 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEQ28205.1 - 0.051 13.4 0.3 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ28206.1 - 8.9e-28 97.5 0.2 1.2e-27 97.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ28206.1 - 9.3e-16 58.0 0.3 8.4e-13 48.5 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ28206.1 - 5e-10 39.7 0.1 1.1e-05 25.6 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ28206.1 - 4.7e-05 22.5 1.0 9.1e-05 21.6 0.1 1.9 2 1 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EEQ28206.1 - 6.6e-05 23.1 0.1 0.011 16.0 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EEQ28206.1 - 0.00023 21.0 0.1 0.15 12.1 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEQ28206.1 - 0.00081 18.3 0.0 0.28 10.0 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EEQ28206.1 - 0.0024 16.8 2.9 1.9 7.3 0.2 3.7 2 2 1 4 4 4 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EEQ28206.1 - 0.012 15.7 0.1 2.8 8.0 0.0 2.5 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EEQ28206.1 - 0.02 13.9 0.4 3.2 6.7 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 EEQ28206.1 - 0.026 13.3 4.1 0.3 9.8 0.3 2.8 2 1 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EEQ28206.1 - 0.11 11.3 7.6 2.2 7.0 0.2 3.9 3 1 0 4 4 4 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EEQ28206.1 - 0.14 10.7 0.1 0.38 9.3 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pkinase PF00069.20 EEQ28209.1 - 2.1e-25 89.3 0.0 1e-24 87.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28209.1 - 3.4e-16 59.0 0.1 2.1e-07 30.3 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Sulfolobus_pRN PF05584.6 EEQ28209.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein APH PF01636.18 EEQ28210.1 - 1.1e-11 44.9 0.0 1.7e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ28210.1 - 3.3e-09 36.6 0.2 1.4e-08 34.5 0.1 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ28210.1 - 9.6e-07 28.1 0.0 0.0002 20.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.6 EEQ28210.1 - 0.098 11.2 0.1 0.25 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF2116 PF09889.4 EEQ28211.1 - 0.03 14.1 0.2 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Sulfotransfer_3 PF13469.1 EEQ28211.1 - 0.22 12.4 4.4 0.37 11.6 3.1 1.4 1 1 0 1 1 1 0 Sulfotransferase family Peptidase_S8 PF00082.17 EEQ28212.1 - 1.5e-49 168.6 2.2 2.2e-49 168.1 1.5 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EEQ28212.1 - 6.4e-30 102.7 0.4 1.4e-29 101.6 0.3 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain FixQ PF05545.6 EEQ28212.1 - 0.09 12.4 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Metallophos PF00149.23 EEQ28213.1 - 9.8e-07 28.3 3.1 0.012 15.0 0.2 2.9 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ28213.1 - 4.3e-06 26.6 0.0 7.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PX PF00787.19 EEQ28214.1 - 1.8e-18 66.4 0.5 4.3e-18 65.1 0.3 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EEQ28214.1 - 6.6e-14 51.7 7.0 2.6e-07 30.1 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF1664 PF07889.7 EEQ28214.1 - 0.062 13.1 1.5 3.4 7.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BAR PF03114.13 EEQ28214.1 - 0.08 12.4 8.3 0.78 9.1 5.8 2.3 1 1 0 1 1 1 0 BAR domain Occludin_ELL PF07303.8 EEQ28214.1 - 0.33 11.6 4.2 1.7 9.4 0.0 2.9 3 0 0 3 3 3 0 Occludin homology domain DUF724 PF05266.9 EEQ28214.1 - 0.51 9.9 3.9 6.5 6.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FAD_binding_3 PF01494.14 EEQ28215.1 - 6.1e-22 78.1 0.0 9.3e-20 70.9 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EEQ28215.1 - 0.0016 17.4 0.1 0.0056 15.6 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein SE PF08491.5 EEQ28215.1 - 0.0019 17.1 0.0 0.0029 16.4 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EEQ28215.1 - 0.0035 16.2 0.0 0.018 13.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEQ28215.1 - 0.0042 16.8 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEQ28215.1 - 0.014 15.3 0.0 0.038 14.0 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEQ28215.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEQ28215.1 - 0.04 13.8 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ28215.1 - 0.049 13.6 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEQ28215.1 - 0.076 11.6 0.1 0.17 10.5 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase tRNA-synt_His PF13393.1 EEQ28216.1 - 7.9e-37 126.9 0.0 1e-30 106.9 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EEQ28216.1 - 1.6e-17 63.6 0.0 2.8e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ28216.1 - 2.1e-12 46.7 0.0 4.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EEQ28216.1 - 0.0005 18.9 0.0 0.02 13.6 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) dUTPase PF00692.14 EEQ28217.1 - 5e-10 38.9 0.0 7.1e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 dUTPase DDE_Tnp_2 PF04693.7 EEQ28217.1 - 0.081 11.9 0.0 0.099 11.6 0.0 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 UCH PF00443.24 EEQ28218.1 - 3.7e-53 180.3 0.5 3.7e-53 180.3 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ28218.1 - 2.7e-22 79.5 0.9 5.1e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EEQ28218.1 - 0.011 14.9 4.9 0.092 12.0 2.5 2.6 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ycf1 PF05758.7 EEQ28218.1 - 0.051 11.2 6.3 0.094 10.4 4.4 1.3 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 EEQ28218.1 - 0.67 8.3 29.6 0.18 10.2 17.8 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Borrelia_P83 PF05262.6 EEQ28218.1 - 6.4 4.9 22.8 12 4.0 15.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.14 EEQ28218.1 - 9 4.0 6.1 16 3.1 4.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Yos1 PF08571.5 EEQ28219.1 - 7.1e-06 26.0 0.0 9.6e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Yos1-like HNH_2 PF13391.1 EEQ28220.1 - 1.8e-11 43.6 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.20 EEQ28221.1 - 2.7e-16 59.5 0.0 2e-07 30.4 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28221.1 - 0.0039 16.3 0.0 1.2 8.1 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Glyco_transf_22 PF03901.12 EEQ28222.1 - 6.3e-35 120.9 20.4 8e-35 120.6 14.2 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamitin PF04912.9 EEQ28223.1 - 2e-31 109.1 2.6 5.1e-15 55.1 0.2 2.2 2 0 0 2 2 2 2 Dynamitin Tropomyosin_1 PF12718.2 EEQ28223.1 - 0.0074 16.1 13.8 0.085 12.6 0.7 3.4 3 0 0 3 3 3 1 Tropomyosin like DivIC PF04977.10 EEQ28223.1 - 0.0098 15.3 13.9 0.74 9.3 0.9 3.5 3 0 0 3 3 3 1 Septum formation initiator GAS PF13851.1 EEQ28223.1 - 0.01 15.0 3.8 0.5 9.5 0.3 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EEQ28223.1 - 0.012 15.2 12.6 0.027 14.2 0.7 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein NUDE_C PF04880.8 EEQ28223.1 - 0.014 15.7 0.2 0.014 15.7 0.1 2.8 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DUF3166 PF11365.3 EEQ28223.1 - 0.023 15.1 0.9 0.023 15.1 0.6 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF3166) DUF4446 PF14584.1 EEQ28223.1 - 0.045 13.5 2.4 4.5 7.1 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF4446) Reo_sigmaC PF04582.7 EEQ28223.1 - 0.074 12.2 4.9 1.5 7.9 1.5 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF4254 PF14063.1 EEQ28223.1 - 0.095 12.3 4.7 2 8.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4254) Filament PF00038.16 EEQ28223.1 - 0.29 10.5 7.9 1.3 8.4 0.3 2.9 3 0 0 3 3 3 0 Intermediate filament protein IncA PF04156.9 EEQ28223.1 - 0.29 10.6 8.7 1.4 8.4 0.6 3.1 2 1 1 3 3 3 0 IncA protein DUF972 PF06156.8 EEQ28223.1 - 0.3 11.4 6.6 3.1 8.1 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 EEQ28223.1 - 0.35 10.5 8.1 0.5 10.0 0.4 2.9 3 0 0 3 3 3 0 Mnd1 family Cep57_CLD_2 PF14197.1 EEQ28223.1 - 0.43 10.5 8.3 1.1 9.2 2.9 3.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Prefoldin PF02996.12 EEQ28223.1 - 0.44 10.2 10.7 2.1 8.0 1.0 3.6 3 0 0 3 3 3 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.4 EEQ28223.1 - 0.53 10.2 6.4 1.4 8.8 0.2 2.6 3 0 0 3 3 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.7 EEQ28223.1 - 0.55 10.6 9.5 2.4 8.6 0.3 4.2 4 0 0 4 4 4 0 SlyX CENP-F_leu_zip PF10473.4 EEQ28223.1 - 0.56 10.0 14.6 0.84 9.4 2.3 3.3 4 0 0 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FH2 PF02181.18 EEQ28223.1 - 0.63 8.8 4.8 0.41 9.4 0.2 2.5 3 0 0 3 3 3 0 Formin Homology 2 Domain Spc24 PF08286.6 EEQ28223.1 - 0.74 9.5 12.9 0.67 9.6 1.7 3.2 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 GrpE PF01025.14 EEQ28223.1 - 0.83 9.1 5.6 3.1 7.3 0.1 3.1 3 0 0 3 3 3 0 GrpE Spectrin PF00435.16 EEQ28223.1 - 0.94 9.7 10.8 6.3 7.1 0.4 3.7 3 1 0 3 3 3 0 Spectrin repeat Fib_alpha PF08702.5 EEQ28223.1 - 0.98 9.5 3.3 4.9 7.2 0.1 3.1 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EEQ28223.1 - 1.2 8.1 9.2 2.3 7.2 0.5 2.6 3 0 0 3 3 3 0 Autophagy protein Apg6 DUF4140 PF13600.1 EEQ28223.1 - 1.3 9.5 16.4 0.5 10.8 1.0 4.3 3 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 EEQ28223.1 - 1.3 8.8 13.4 3.3 7.5 0.2 3.4 3 1 1 4 4 4 0 Prefoldin subunit THOC7 PF05615.8 EEQ28223.1 - 1.4 9.1 9.7 0.22 11.7 1.4 2.9 3 0 0 3 3 3 0 Tho complex subunit 7 COG2 PF06148.6 EEQ28223.1 - 3.1 7.6 5.1 7.2 6.4 0.2 3.1 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.7 EEQ28223.1 - 4.2 7.1 10.1 0.41 10.4 0.3 3.5 3 2 0 3 3 3 0 Laminin Domain II DUF904 PF06005.7 EEQ28223.1 - 4.4 7.6 10.1 25 5.2 3.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Ax_dynein_light PF10211.4 EEQ28223.1 - 4.6 7.0 9.4 8.2 6.2 0.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain GvpK PF05121.7 EEQ28223.1 - 8.1 6.3 9.3 1.1 9.1 1.0 3.1 4 1 0 4 4 2 0 Gas vesicle protein K Peptidase_M24 PF00557.19 EEQ28225.1 - 3.1e-39 134.6 0.3 4.4e-39 134.2 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4557 PF15101.1 EEQ28225.1 - 0.039 13.7 0.1 0.062 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Nop53 PF07767.6 EEQ28225.1 - 0.3 10.0 7.4 0.47 9.3 5.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Spt5_N PF11942.3 EEQ28225.1 - 2.3 8.8 8.7 0.61 10.7 2.6 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Aldedh PF00171.17 EEQ28226.1 - 5.5e-136 453.5 0.8 6.7e-136 453.2 0.6 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase_C PF00433.19 EEQ28226.1 - 0.031 14.8 0.0 0.085 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Calreticulin PF00262.13 EEQ28227.1 - 1.2e-165 550.5 17.7 1.2e-165 550.5 12.3 1.7 2 0 0 2 2 2 1 Calreticulin family DUF2273 PF10031.4 EEQ28227.1 - 0.58 9.8 4.2 1 9.0 2.9 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Aldolase_II PF00596.16 EEQ28228.1 - 1.4e-30 106.2 0.0 2e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.5 EEQ28229.1 - 1.2e-72 243.9 7.8 2e-72 243.2 5.4 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EEQ28229.1 - 5.2e-25 87.4 0.0 1.3e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 PX domain Tissue_fac PF01108.12 EEQ28230.1 - 0.05 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Tissue factor Flavin_Reduct PF01613.13 EEQ28231.1 - 5e-25 88.1 3.6 2.2e-24 86.0 2.5 2.0 1 1 0 1 1 1 1 Flavin reductase like domain TBPIP PF07106.8 EEQ28232.1 - 0.25 10.8 12.8 0.032 13.7 4.6 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fmp27_WPPW PF10359.4 EEQ28232.1 - 6.4 5.0 14.3 0.2 10.0 1.8 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Exonuc_VII_L PF02601.10 EEQ28232.1 - 8.9 5.3 21.6 91 2.0 15.2 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit 4HBT_2 PF13279.1 EEQ28233.1 - 6.7e-05 23.3 0.0 0.00017 22.0 0.0 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily Complex1_LYR_2 PF13233.1 EEQ28234.1 - 6.8e-09 36.1 0.0 7.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EEQ28234.1 - 1.8e-05 24.8 0.1 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEQ28234.1 - 4.3e-05 23.2 0.1 8.2e-05 22.3 0.1 1.5 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Methyltransf_25 PF13649.1 EEQ28235.1 - 9.8e-08 32.2 0.0 1.9e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ28235.1 - 5.8e-07 29.9 0.0 1.2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ28235.1 - 0.00017 21.3 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ28235.1 - 0.00026 20.6 0.0 0.00047 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ28235.1 - 0.00029 20.0 0.0 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEQ28235.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ28235.1 - 0.0017 18.9 0.0 0.0033 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ28235.1 - 0.005 17.2 0.3 0.011 16.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEQ28235.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pex14_N PF04695.8 EEQ28235.1 - 0.42 10.6 3.6 0.58 10.2 0.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Exo_endo_phos PF03372.18 EEQ28236.1 - 1.3e-20 74.4 0.0 1.9e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EEQ28236.1 - 1.1e-12 47.2 9.2 5.2e-08 32.3 1.5 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ28236.1 - 3.1e-09 36.4 14.0 4.5e-07 29.5 3.5 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EEQ28236.1 - 7.2e-06 25.3 5.4 0.029 14.3 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EEQ28236.1 - 0.00074 19.3 11.2 0.12 12.6 0.0 4.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EEQ28236.1 - 0.37 11.0 0.0 0.37 11.0 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeat MFS_1 PF07690.11 EEQ28237.1 - 3.1e-44 151.1 46.0 4.5e-44 150.6 31.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ28237.1 - 6.4e-21 74.1 17.1 4.3e-20 71.4 11.3 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ28237.1 - 2.1e-18 66.1 0.2 2.1e-18 66.1 0.1 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter DUF3357 PF11837.3 EEQ28237.1 - 0.17 11.7 0.7 0.7 9.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) 2TM PF13239.1 EEQ28237.1 - 5.5 7.1 10.8 17 5.5 3.7 3.8 3 0 0 3 3 3 0 2TM domain GCD14 PF08704.5 EEQ28238.1 - 5.6e-07 29.3 0.1 0.0015 18.1 0.0 2.6 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EEQ28238.1 - 0.013 15.1 0.0 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.23 EEQ28239.1 - 3.3e-13 49.5 0.6 5.8e-13 48.6 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ28239.1 - 5.5e-05 23.0 0.2 9.6e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_1 PF00175.16 EEQ28240.1 - 4.3e-05 24.0 0.0 0.26 11.8 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EEQ28240.1 - 0.00029 20.7 0.2 0.022 14.6 0.0 2.5 2 1 0 2 2 2 1 Ferric reductase NAD binding domain G6PD_N PF00479.17 EEQ28240.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain COesterase PF00135.23 EEQ28242.1 - 2.7e-64 217.7 0.1 6.1e-64 216.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ28242.1 - 7.9e-06 25.5 0.0 2.2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold E1-E2_ATPase PF00122.15 EEQ28244.1 - 1e-52 178.4 0.7 1e-52 178.4 0.5 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 EEQ28244.1 - 6.4e-44 147.9 0.0 2.9e-11 43.3 0.1 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 EEQ28244.1 - 2.8e-39 135.7 2.5 2.8e-39 135.7 0.1 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ28244.1 - 5.7e-14 52.7 0.0 1.4e-13 51.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ28244.1 - 1e-05 25.2 0.1 0.0037 16.8 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase B12-binding PF02310.14 EEQ28244.1 - 0.024 14.5 0.0 24 4.8 0.0 4.5 5 0 0 5 5 5 0 B12 binding domain DUF2089 PF09862.4 EEQ28244.1 - 0.33 10.7 0.5 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) PCI PF01399.22 EEQ28245.1 - 0.00031 21.0 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 EEQ28246.1 - 2.6e-12 46.8 0.0 1.6e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.20 EEQ28247.1 - 7.4e-26 89.8 0.8 1.4e-25 89.0 0.6 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EEQ28247.1 - 2.5e-08 33.9 0.1 5.4e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ28247.1 - 5.6e-08 32.6 0.1 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Rad1 PF02144.11 EEQ28248.1 - 1.2e-87 293.1 0.0 1.4e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 SbcCD_C PF13558.1 EEQ28249.1 - 9.1e-12 44.7 0.0 2.6e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EEQ28249.1 - 1e-08 35.7 10.5 4.9e-07 30.2 0.1 8.9 2 1 2 4 4 4 2 AAA domain SMC_N PF02463.14 EEQ28249.1 - 0.00041 19.6 0.0 0.00041 19.6 0.0 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ28249.1 - 0.0029 17.6 1.7 0.0029 17.6 1.2 4.4 3 2 1 4 4 4 1 AAA domain AAA_13 PF13166.1 EEQ28249.1 - 0.47 8.8 120.5 0.2 10.0 12.8 7.2 2 1 3 6 6 6 0 AAA domain PPP4R2 PF09184.6 EEQ28250.1 - 6.3e-10 39.0 0.3 6.3e-10 39.0 0.2 2.3 2 1 0 2 2 2 1 PPP4R2 zf-H2C2_2 PF13465.1 EEQ28252.1 - 4.4e-13 48.8 7.4 2e-07 30.9 0.1 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ28252.1 - 6.4e-12 45.0 13.4 1.4e-05 25.1 1.6 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ28252.1 - 1.7e-10 40.5 13.9 4e-05 23.6 1.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ28252.1 - 8.1e-07 29.0 1.3 0.092 12.9 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ28252.1 - 0.00014 21.9 1.7 0.011 15.9 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EEQ28252.1 - 0.022 14.9 0.6 0.063 13.5 0.4 1.8 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Elf1 PF05129.8 EEQ28252.1 - 0.063 12.9 0.5 0.12 12.0 0.4 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 EEQ28252.1 - 0.098 12.7 1.6 0.19 11.8 1.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EEQ28252.1 - 1.8 8.3 12.4 1.7 8.3 0.4 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Pkinase PF00069.20 EEQ28254.1 - 2.9e-53 180.6 0.1 1.7e-36 125.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28254.1 - 1.5e-25 89.7 0.0 4e-24 85.0 0.0 3.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ28254.1 - 4.6e-05 22.5 0.0 0.00013 21.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ28254.1 - 0.00065 19.4 0.0 0.0033 17.2 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kelch_5 PF13854.1 EEQ28255.1 - 0.00036 20.3 0.0 0.064 13.2 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 EEQ28255.1 - 0.0031 17.2 14.3 0.0085 15.8 0.1 5.2 5 1 0 5 5 5 2 Galactose oxidase, central domain DUF3246 PF11596.3 EEQ28255.1 - 0.0039 16.5 3.2 0.0094 15.2 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Kelch_2 PF07646.10 EEQ28255.1 - 0.0043 16.7 1.2 0.93 9.3 0.0 3.6 3 0 0 3 3 3 1 Kelch motif SKG6 PF08693.5 EEQ28255.1 - 0.058 12.7 2.4 0.13 11.5 1.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain BPL_LplA_LipB PF03099.14 EEQ28256.1 - 8.6e-12 45.1 0.0 2.4e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 EEQ28257.1 - 6.8e-130 432.5 0.0 8.7e-130 432.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ima1_N PF09779.4 EEQ28258.1 - 5.9e-42 143.2 9.5 1.5e-41 141.9 6.6 1.8 1 0 0 1 1 1 1 Ima1 N-terminal domain C1_1 PF00130.17 EEQ28258.1 - 0.84 9.4 8.8 0.2 11.3 1.6 2.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Alg14 PF08660.6 EEQ28259.1 - 2.2e-48 164.4 0.0 2.9e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PNK3P PF08645.6 EEQ28261.1 - 1.8e-47 160.7 0.0 3.8e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EEQ28261.1 - 1.4e-30 106.0 0.0 5.4e-30 104.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEQ28261.1 - 7e-11 41.8 2.1 1.2e-07 31.1 0.0 2.7 2 1 1 3 3 3 2 Chromatin associated protein KTI12 AAA_22 PF13401.1 EEQ28261.1 - 0.0028 17.7 0.0 0.0096 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ28261.1 - 0.0042 16.2 0.0 0.014 14.5 0.0 1.7 1 1 1 2 2 2 1 Zeta toxin HAD_2 PF13419.1 EEQ28261.1 - 0.0079 16.4 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase AAA_29 PF13555.1 EEQ28261.1 - 0.033 13.7 0.1 0.21 11.1 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EEQ28261.1 - 0.063 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EEQ28261.1 - 0.1 12.8 2.0 3.1 8.1 0.2 2.7 2 1 1 3 3 3 0 AAA domain Med18 PF09637.5 EEQ28262.1 - 7.3e-44 150.1 0.0 8.2e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 EEQ28263.1 - 2.2e-39 134.9 0.2 2.5e-39 134.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 EEQ28264.1 - 2.5e-82 275.8 2.8 7.6e-79 264.4 1.9 2.6 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RGS PF00615.14 EEQ28266.1 - 2.2e-10 40.6 0.0 3.6e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 EEQ28269.1 - 8e-36 123.5 0.0 9.9e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28269.1 - 2.5e-14 53.0 0.0 3.1e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ28269.1 - 0.0025 17.5 0.1 0.13 11.9 0.0 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Rtt106 PF08512.7 EEQ28270.1 - 1.2e-27 95.7 0.1 2.1e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like KOW PF00467.24 EEQ28271.1 - 2.8e-08 33.1 0.6 7.1e-08 31.8 0.4 1.7 1 0 0 1 1 1 1 KOW motif Ras PF00071.17 EEQ28272.1 - 1.9e-55 186.6 0.0 2.2e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ28272.1 - 4.8e-15 56.1 0.0 7.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ28272.1 - 8.6e-07 28.3 0.0 1.5e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ28272.1 - 0.002 17.3 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEQ28272.1 - 0.019 14.0 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EEQ28272.1 - 0.11 12.0 0.0 11 5.5 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Podoplanin PF05808.6 EEQ28273.1 - 0.00071 19.1 0.3 0.0013 18.3 0.2 1.4 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.6 EEQ28273.1 - 0.0044 16.8 2.6 0.0087 15.8 1.8 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) TMEM154 PF15102.1 EEQ28273.1 - 0.035 13.8 0.2 0.055 13.1 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family VSP PF03302.8 EEQ28273.1 - 0.074 11.6 0.3 0.11 11.1 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4124 PF13511.1 EEQ28273.1 - 0.094 12.7 1.5 0.2 11.6 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4124) Amnionless PF14828.1 EEQ28273.1 - 0.14 10.6 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless CytB6-F_Fe-S PF08802.5 EEQ28273.1 - 1.1 9.3 5.5 0.17 11.9 0.6 2.1 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Aldedh PF00171.17 EEQ28274.1 - 1e-143 479.0 0.0 1.2e-143 478.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1712 PF08217.6 EEQ28275.1 - 1.4e-18 66.5 0.0 2.8e-18 65.5 0.0 1.4 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 EEQ28276.1 - 1.2e-16 60.8 0.1 2.3e-16 59.8 0.1 1.6 1 1 0 1 1 1 1 Formyl transferase adh_short PF00106.20 EEQ28277.1 - 3e-15 56.5 7.0 7.1e-12 45.5 0.6 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ28277.1 - 9.5e-14 51.7 2.4 1.2e-07 31.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEQ28277.1 - 1.1e-05 24.9 0.2 3.8e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EEQ28277.1 - 0.00018 21.2 0.6 0.00026 20.7 0.2 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEQ28277.1 - 0.024 14.4 0.3 0.084 12.6 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 EEQ28278.1 - 8.3e-24 83.9 0.0 1.3e-18 66.8 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EEQ28279.1 - 2.3e-26 92.3 0.0 5e-26 91.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEQ28280.1 - 1.2e-48 165.8 0.0 3.2e-28 98.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 EMP24_GP25L PF01105.19 EEQ28281.1 - 6.2e-53 179.2 0.0 8.6e-53 178.7 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PspB PF06667.7 EEQ28281.1 - 0.061 13.2 0.6 0.13 12.1 0.4 1.6 1 0 0 1 1 1 0 Phage shock protein B Peptidase_S46 PF10459.4 EEQ28281.1 - 0.063 11.7 0.8 0.11 10.8 0.2 1.5 1 1 1 2 2 2 0 Peptidase S46 Myb_DNA-bind_6 PF13921.1 EEQ28282.1 - 0.026 14.6 0.6 0.19 11.8 0.0 2.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ28282.1 - 0.084 12.9 0.1 1.3 9.1 0.0 2.7 2 1 0 2 2 2 0 Myb-like DNA-binding domain V_ATPase_I PF01496.14 EEQ28282.1 - 4.1 5.1 10.0 0.39 8.5 3.2 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Meth_synt_2 PF01717.13 EEQ28284.1 - 7e-143 475.4 0.0 1e-138 461.7 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EEQ28284.1 - 2.5e-121 404.7 0.0 8.6e-110 366.8 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EEQ28284.1 - 0.0006 18.8 0.0 0.2 10.5 0.0 2.9 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) LYTB PF02401.13 EEQ28284.1 - 0.14 11.0 0.7 5.8 5.7 0.0 2.2 2 0 0 2 2 2 0 LytB protein Steroid_dh PF02544.11 EEQ28285.1 - 5.8e-09 35.8 7.9 0.0024 17.6 0.3 3.9 3 2 1 4 4 4 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EEQ28285.1 - 0.049 12.9 0.2 0.26 10.5 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ufd2P_core PF10408.4 EEQ28286.1 - 5.1e-184 613.0 13.2 6.1e-184 612.7 9.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EEQ28286.1 - 1.4e-23 82.6 2.2 6.9e-23 80.3 0.1 2.8 3 0 0 3 3 3 1 U-box domain Pex14_N PF04695.8 EEQ28286.1 - 0.33 11.0 8.9 7.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1977 PF09320.6 EEQ28287.1 - 9.1e-29 99.8 0.1 1.5e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EEQ28287.1 - 5.3e-23 80.5 0.4 9e-23 79.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 EEQ28287.1 - 0.17 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF2416 PF10315.4 EEQ28288.1 - 1.6e-06 28.3 0.2 6.8e-06 26.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2416) CTP_transf_2 PF01467.21 EEQ28289.1 - 0.00022 21.3 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Ydc2-catalyt PF09159.5 EEQ28291.1 - 8.9e-96 320.5 0.0 1.1e-95 320.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EEQ28291.1 - 2.2e-06 27.5 0.0 0.26 11.1 0.0 3.3 3 0 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.22 EEQ28291.1 - 0.00011 21.5 0.4 0.00025 20.4 0.3 1.6 1 0 0 1 1 1 1 SAP domain Tcp11 PF05794.8 EEQ28292.1 - 1.2e-78 264.8 0.0 1.9e-78 264.1 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 Mito_fiss_reg PF05308.6 EEQ28292.1 - 2.7 7.2 10.4 23 4.2 5.9 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Peptidase_S10 PF00450.17 EEQ28293.1 - 2.1e-80 270.9 0.0 5.4e-80 269.5 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEQ28293.1 - 0.067 13.0 0.0 1 9.1 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family SOG2 PF10428.4 EEQ28294.1 - 5.3e-100 335.1 0.7 5.3e-100 335.1 0.5 3.3 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 EEQ28294.1 - 2.9e-16 58.6 5.0 2.1e-07 30.3 1.1 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ28294.1 - 1.1e-12 47.5 2.1 8e-07 28.7 0.9 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EEQ28294.1 - 7.4e-08 31.4 9.1 0.023 14.6 0.1 6.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EEQ28294.1 - 5.8e-05 22.6 3.7 3.4 8.2 0.1 5.9 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EEQ28294.1 - 0.016 15.1 4.4 0.88 9.8 0.1 4.8 4 1 1 5 5 5 0 Leucine Rich repeat ARID PF01388.16 EEQ28294.1 - 0.069 13.0 0.1 0.51 10.2 0.0 2.5 3 0 0 3 3 3 0 ARID/BRIGHT DNA binding domain MRP-S25 PF13741.1 EEQ28295.1 - 3.2e-88 295.1 4.6 3.8e-88 294.8 3.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EEQ28295.1 - 0.018 14.9 1.3 5.4 6.9 0.0 2.6 2 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 PPR_3 PF13812.1 EEQ28296.1 - 4e-11 42.2 0.8 0.031 14.5 0.0 5.9 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEQ28296.1 - 1.1e-10 41.3 0.5 0.00079 19.3 0.0 4.6 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 EEQ28296.1 - 1.4e-07 30.9 0.9 0.098 12.6 0.1 4.4 4 0 0 4 4 4 2 PPR repeat ERp29 PF07749.7 EEQ28296.1 - 0.12 13.0 0.9 47 4.7 0.0 3.4 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Helicase_C PF00271.26 EEQ28297.1 - 1.3e-17 63.4 0.0 1.4e-14 53.6 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ28297.1 - 1.5e-16 60.3 0.0 8e-16 57.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.24 EEQ28298.1 - 1.3e-08 34.3 0.0 5.5e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EEQ28298.1 - 3.6e-05 23.2 0.4 0.00027 20.5 0.1 2.4 3 0 0 3 3 3 1 KH domain SF3b1 PF08920.5 EEQ28298.1 - 1.1 9.3 5.8 2.8 7.9 3.9 2.0 1 1 0 1 1 1 0 Splicing factor 3B subunit 1 GRP PF07172.6 EEQ28298.1 - 3.9 8.0 19.8 0.09 13.2 8.6 2.0 2 0 0 2 2 2 0 Glycine rich protein family ALS_ss_C PF10369.4 EEQ28299.1 - 2.8e-19 68.5 0.0 7e-18 64.1 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EEQ28299.1 - 4.9e-11 41.8 0.1 9e-11 41.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EEQ28299.1 - 5.2e-09 35.7 0.2 1.1e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 EEQ28299.1 - 0.017 14.8 0.1 6.5 6.5 0.0 2.6 2 0 0 2 2 2 0 ACT domain Cu-oxidase_3 PF07732.10 EEQ28303.1 - 2.6e-38 130.3 0.1 9.1e-37 125.3 0.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEQ28303.1 - 5.4e-38 129.6 4.4 9.4e-36 122.3 1.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EEQ28303.1 - 6.2e-25 87.9 0.0 1.9e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase DUF3712 PF12505.3 EEQ28304.1 - 4.1e-07 30.0 0.3 0.0025 17.8 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EEQ28304.1 - 0.011 16.0 2.9 1.4 9.3 0.1 3.7 4 0 0 4 4 4 0 Late embryogenesis abundant protein CD34_antigen PF06365.7 EEQ28304.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family OTCace_N PF02729.16 EEQ28305.1 - 3.2e-41 140.2 0.0 4.6e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EEQ28305.1 - 1.6e-40 138.5 0.0 3.2e-40 137.6 0.0 1.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3984 PF13136.1 EEQ28306.1 - 5.2e-104 347.9 18.8 8.5e-104 347.2 13.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Ndc1_Nup PF09531.5 EEQ28307.1 - 9.6e-152 506.4 0.1 1.1e-151 506.3 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EEQ28308.1 - 6.5e-22 77.4 2.5 6.5e-22 77.4 1.7 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EEQ28308.1 - 4.3e-17 61.5 2.8 4.3e-17 61.5 1.9 2.4 3 1 1 4 4 4 1 SNARE domain Synaptobrevin PF00957.16 EEQ28308.1 - 0.00011 21.7 1.0 0.00038 19.9 0.2 2.2 2 0 0 2 2 2 1 Synaptobrevin Syntaxin PF00804.20 EEQ28308.1 - 0.00099 19.2 0.2 0.00099 19.2 0.2 2.6 1 1 0 2 2 2 1 Syntaxin DUF883 PF05957.8 EEQ28308.1 - 0.0012 19.1 7.8 0.26 11.7 0.0 3.2 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF883) DUF2951 PF11166.3 EEQ28308.1 - 0.023 14.5 5.4 0.66 9.8 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) AAA_13 PF13166.1 EEQ28308.1 - 0.043 12.2 6.0 0.068 11.6 4.1 1.3 1 1 0 1 1 1 0 AAA domain Herpes_US9 PF06072.6 EEQ28308.1 - 0.06 13.1 0.8 0.12 12.1 0.6 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF912 PF06024.7 EEQ28308.1 - 0.077 13.0 0.2 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF552 PF04472.7 EEQ28308.1 - 0.09 12.7 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF552) DUF2077 PF09850.4 EEQ28308.1 - 0.13 11.6 1.7 8 5.8 0.0 3.0 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Fib_alpha PF08702.5 EEQ28308.1 - 0.34 11.0 4.2 4.1 7.5 0.1 3.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family TarH PF02203.10 EEQ28308.1 - 0.37 10.6 5.3 3.3 7.5 1.2 3.0 2 1 1 3 3 3 0 Tar ligand binding domain homologue Rifin_STEVOR PF02009.11 EEQ28308.1 - 2.2 7.8 5.6 12 5.4 2.2 2.7 2 1 1 3 3 3 0 Rifin/stevor family Cyto_heme_lyase PF01265.12 EEQ28309.1 - 1.3e-75 254.3 0.0 6.4e-74 248.8 0.0 1.9 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 EEQ28310.1 - 1.2e-10 41.2 1.2 2.8e-10 40.1 0.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain PDGLE PF13190.1 EEQ28310.1 - 0.045 13.4 0.2 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 PDGLE domain IKI3 PF04762.7 EEQ28311.1 - 0 1060.0 0.0 0 1059.5 0.0 1.2 1 0 0 1 1 1 1 IKI3 family COX7C PF02935.11 EEQ28312.1 - 2.9e-13 49.3 2.4 3.9e-13 48.9 1.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.1 EEQ28313.1 - 1.2e-101 339.3 0.1 1.9e-101 338.7 0.1 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EEQ28313.1 - 5.4e-65 217.9 1.7 1.4e-64 216.6 1.2 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EEQ28313.1 - 1.3e-21 76.8 0.1 4.4e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ28313.1 - 1.3e-06 28.1 0.0 3.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ28313.1 - 0.0035 17.2 0.0 0.031 14.1 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EEQ28313.1 - 0.063 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EEQ28313.1 - 0.19 11.5 0.0 0.47 10.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain BPD_transp_1 PF00528.17 EEQ28314.1 - 0.033 13.7 0.5 0.042 13.3 0.3 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Pkinase PF00069.20 EEQ28315.1 - 2.9e-14 52.8 0.1 1.1e-13 50.9 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28315.1 - 5.3e-10 38.8 0.0 8.5e-10 38.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EEQ28315.1 - 0.00012 21.7 0.1 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EEQ28315.1 - 0.011 15.5 0.1 0.026 14.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cut8_C PF08559.5 EEQ28316.1 - 1.8e-33 115.3 0.0 2.9e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EEQ28316.1 - 2.1e-17 62.6 1.0 6.3e-17 61.0 0.7 1.9 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EEQ28316.1 - 5.7e-10 39.0 3.7 1.4e-09 37.7 2.5 1.7 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Motile_Sperm PF00635.21 EEQ28317.1 - 1.4e-05 24.6 0.1 0.13 11.9 0.0 2.5 2 1 0 2 2 2 2 MSP (Major sperm protein) domain DUF2077 PF09850.4 EEQ28317.1 - 0.091 12.1 0.2 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) UBA PF00627.26 EEQ28318.1 - 0.00049 19.8 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.21 EEQ28318.1 - 0.015 15.5 0.2 0.029 14.7 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3595 PF12166.3 EEQ28318.1 - 0.017 13.9 3.1 0.021 13.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) zf-C2H2_jaz PF12171.3 EEQ28318.1 - 0.027 14.6 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding GspL_C PF12693.2 EEQ28318.1 - 0.038 13.7 1.2 0.038 13.7 0.9 2.3 2 1 0 2 2 2 0 GspL periplasmic domain zf-C2H2_2 PF12756.2 EEQ28318.1 - 0.12 12.4 0.2 0.12 12.4 0.1 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF342 PF03961.8 EEQ28318.1 - 2 6.7 18.7 3.1 6.0 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CRT10 PF08728.5 EEQ28318.1 - 2.9 5.7 7.9 3.4 5.5 5.5 1.1 1 0 0 1 1 1 0 CRT10 Rad52_Rad22 PF04098.10 EEQ28319.1 - 2.3e-39 134.5 0.7 7.5e-22 77.7 0.5 2.2 1 1 1 2 2 2 2 Rad52/22 family double-strand break repair protein Aa_trans PF01490.13 EEQ28321.1 - 2.5e-79 266.6 31.6 3e-79 266.4 21.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein BNIP3 PF06553.7 EEQ28321.1 - 0.1 11.9 2.3 0.2 11.0 1.6 1.4 1 0 0 1 1 1 0 BNIP3 Y_phosphatase2 PF03162.8 EEQ28323.1 - 8.7e-30 103.2 0.1 7.6e-28 96.9 0.0 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EEQ28323.1 - 0.0035 16.9 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEQ28323.1 - 0.004 16.5 0.0 0.013 14.8 0.0 1.7 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEQ28323.1 - 0.013 15.7 0.0 0.04 14.1 0.0 1.7 1 1 1 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.7 EEQ28323.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TatD_DNase PF01026.16 EEQ28324.1 - 2e-48 164.8 0.0 2.4e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.13 EEQ28325.1 - 5.5e-112 374.1 0.0 6.7e-112 373.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEQ28325.1 - 3.2e-15 55.6 0.0 5.9e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EEQ28325.1 - 0.00037 19.5 0.0 0.00058 18.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EEQ28325.1 - 0.00064 18.8 0.0 0.045 12.8 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.10 EEQ28325.1 - 0.0017 17.6 0.1 0.0074 15.4 0.0 1.8 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.20 EEQ28325.1 - 0.038 12.8 0.2 0.038 12.8 0.1 2.1 3 1 1 4 4 4 0 IMP dehydrogenase / GMP reductase domain BtpA PF03437.10 EEQ28325.1 - 0.11 11.6 0.0 0.66 9.1 0.0 2.0 2 0 0 2 2 2 0 BtpA family SAP PF02037.22 EEQ28326.1 - 2e-10 39.9 0.0 3.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 SAP domain PCMT PF01135.14 EEQ28326.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_Rpb1_5 PF04998.12 EEQ28327.1 - 6.6e-88 294.5 0.0 1.9e-87 293.0 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EEQ28327.1 - 5.1e-84 282.4 0.0 8.3e-84 281.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EEQ28327.1 - 6.2e-67 224.6 0.0 1.2e-66 223.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EEQ28327.1 - 2e-34 118.6 0.0 3.9e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EEQ28327.1 - 7.6e-26 89.9 0.3 2.4e-25 88.3 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Asp PF00026.18 EEQ28328.1 - 4.5e-46 157.5 0.1 5.6e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEQ28328.1 - 0.042 13.3 0.0 0.83 9.1 0.0 2.2 1 1 0 2 2 2 0 Xylanase inhibitor C-terminal Herpes_BLLF1 PF05109.8 EEQ28328.1 - 0.68 7.8 12.2 0.96 7.3 8.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) CarboxypepD_reg PF13620.1 EEQ28329.1 - 0.062 13.3 1.9 0.21 11.6 0.5 2.2 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Vfa1 PF08432.5 EEQ28330.1 - 1.9e-63 213.7 27.5 2.7e-63 213.2 19.1 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 EEQ28330.1 - 0.022 13.7 10.0 0.029 13.3 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Herpes_Helicase PF02689.9 EEQ28330.1 - 0.079 10.6 4.9 0.099 10.3 3.4 1.0 1 0 0 1 1 1 0 Helicase GAGA_bind PF06217.7 EEQ28330.1 - 0.087 12.7 14.2 0.1 12.5 9.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family MIP-T3 PF10243.4 EEQ28330.1 - 0.1 11.0 38.0 0.13 10.7 26.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EEQ28330.1 - 0.12 10.8 22.5 0.14 10.5 15.6 1.1 1 0 0 1 1 1 0 Daxx Family Mnd1 PF03962.10 EEQ28330.1 - 0.14 11.8 21.9 0.2 11.2 15.2 1.2 1 0 0 1 1 1 0 Mnd1 family SET PF00856.23 EEQ28330.1 - 0.18 12.1 5.3 0.25 11.6 3.6 1.2 1 0 0 1 1 1 0 SET domain NPR3 PF03666.8 EEQ28330.1 - 0.2 10.1 15.2 0.25 9.8 10.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.12 EEQ28330.1 - 0.25 11.1 9.7 0.33 10.7 6.7 1.4 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 EEQ28330.1 - 0.3 8.7 21.0 0.35 8.5 14.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF262 PF03235.9 EEQ28330.1 - 0.36 10.7 10.1 0.43 10.5 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 CDC45 PF02724.9 EEQ28330.1 - 0.37 8.7 25.3 0.45 8.4 17.6 1.0 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 EEQ28330.1 - 0.43 9.3 19.5 0.54 9.0 13.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Zip PF02535.17 EEQ28330.1 - 0.89 8.4 4.6 1 8.2 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2201_N PF13203.1 EEQ28330.1 - 1.3 8.1 11.2 1.6 7.8 7.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Cupin_8 PF13621.1 EEQ28330.1 - 2.1 7.7 8.8 2.6 7.4 6.1 1.3 1 0 0 1 1 1 0 Cupin-like domain U79_P34 PF03064.11 EEQ28330.1 - 2.2 7.7 24.1 3.9 6.9 16.7 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GCD14 PF08704.5 EEQ28330.1 - 2.6 7.4 10.7 4 6.8 7.4 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF2413 PF10310.4 EEQ28330.1 - 4.5 5.9 24.2 5.9 5.5 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Paramyxo_ncap PF00973.14 EEQ28330.1 - 4.8 5.7 13.1 5.8 5.4 9.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Neur_chan_memb PF02932.11 EEQ28330.1 - 5.4 6.8 12.0 6.8 6.5 8.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATP11 PF06644.6 EEQ28330.1 - 7.9 5.8 20.8 11 5.4 14.4 1.2 1 0 0 1 1 1 0 ATP11 protein RP-C_C PF11800.3 EEQ28330.1 - 9.2 5.9 11.2 12 5.5 7.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region RNA_pol_Rpb1_5 PF04998.12 EEQ28330.1 - 9.3 5.4 11.9 12 5.0 8.3 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DSPc PF00782.15 EEQ28331.1 - 1.2e-22 79.9 0.0 1.5e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EEQ28331.1 - 0.0031 16.4 0.0 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EEQ28331.1 - 0.0097 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEQ28331.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-C2H2_4 PF13894.1 EEQ28333.1 - 0.00071 19.7 22.6 0.048 13.9 3.0 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ28333.1 - 0.0044 17.2 0.9 0.0044 17.2 0.6 3.5 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EEQ28333.1 - 0.0045 17.1 4.8 0.013 15.6 3.3 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding NosL PF05573.7 EEQ28333.1 - 0.0096 15.6 0.0 0.0096 15.6 0.0 1.9 2 0 0 2 2 2 1 NosL DUF2614 PF11023.3 EEQ28333.1 - 0.26 11.0 0.6 0.45 10.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) zf-C2H2 PF00096.21 EEQ28333.1 - 3 8.3 26.0 0.037 14.3 3.2 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EEQ28333.1 - 3.1 7.8 9.1 9.5 6.2 0.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.7 EEQ28333.1 - 9.8 6.0 10.7 12 5.7 0.8 2.5 1 1 1 2 2 2 0 zinc-ribbons FA_desaturase PF00487.19 EEQ28334.1 - 1e-27 97.1 11.1 2.1e-27 96.1 7.7 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EEQ28334.1 - 8.6e-19 66.4 0.4 1.7e-18 65.5 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ABC1 PF03109.11 EEQ28335.1 - 4.1e-33 113.8 0.2 8.6e-33 112.8 0.0 1.6 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.17 EEQ28335.1 - 0.013 14.8 0.0 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Anp1 PF03452.9 EEQ28336.1 - 8.8e-95 316.9 2.1 1.7e-93 312.6 1.5 2.0 1 1 0 1 1 1 1 Anp1 Ecm33 PF12454.3 EEQ28337.1 - 1.7e-16 59.8 3.2 5.3e-16 58.2 0.2 2.7 1 1 1 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EEQ28337.1 - 3.3e-10 39.9 1.1 0.84 9.6 0.0 5.4 1 1 4 5 5 5 5 Receptor L domain HhH-GPD PF00730.20 EEQ28338.1 - 3.4e-15 56.2 0.0 6.7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UCR_14kD PF02271.11 EEQ28339.1 - 4.5e-43 145.2 0.2 5.2e-43 145.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 EEQ28340.1 - 1.8e-66 219.9 0.0 9e-22 76.6 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein CHD5 PF04420.9 EEQ28341.1 - 6.9e-57 191.6 2.2 8.3e-57 191.3 1.6 1.1 1 0 0 1 1 1 1 CHD5-like protein SUI1 PF01253.17 EEQ28342.1 - 1.6e-14 53.4 0.0 4.2e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Trypsin PF00089.21 EEQ28343.1 - 1.9e-07 30.9 0.3 4.7e-07 29.6 0.2 1.6 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EEQ28343.1 - 0.0052 16.7 0.0 0.018 15.0 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Ank PF00023.25 EEQ28345.1 - 6.9e-13 47.7 4.8 5e-06 26.0 1.4 2.7 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EEQ28345.1 - 7.6e-11 41.8 0.2 7.6e-11 41.8 0.1 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.2 EEQ28345.1 - 1.8e-10 41.0 0.0 3.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ28345.1 - 1.4e-08 34.6 4.7 4.4e-05 23.5 0.7 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ28345.1 - 7.8e-08 31.8 1.2 0.0031 17.6 0.5 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EEQ28345.1 - 1.1e-06 28.9 0.9 3.4e-06 27.4 0.3 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Bap31 PF05529.7 EEQ28345.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TRAPPC10 PF12584.3 EEQ28346.1 - 5.2e-38 129.8 0.0 1e-37 128.8 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Ribosomal_60s PF00428.14 EEQ28346.1 - 0.02 15.2 11.1 0.14 12.5 5.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Foie-gras_1 PF11817.3 EEQ28346.1 - 0.03 13.8 0.2 0.055 12.9 0.1 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 DUF2151 PF10221.4 EEQ28346.1 - 0.08 11.1 0.7 0.13 10.4 0.5 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator NARP1 PF12569.3 EEQ28346.1 - 0.084 11.6 0.3 0.14 10.8 0.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sigma70_ner PF04546.8 EEQ28346.1 - 0.13 11.8 4.9 0.31 10.6 3.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.3 EEQ28346.1 - 1.4 8.8 13.9 2.9 7.7 9.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 EEQ28346.1 - 6.8 4.4 11.0 11 3.8 7.6 1.2 1 0 0 1 1 1 0 Nop14-like family FA_desaturase PF00487.19 EEQ28347.1 - 6.6e-23 81.4 13.1 1e-22 80.8 9.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EEQ28347.1 - 3.1e-08 33.7 0.0 6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Rad51 PF08423.6 EEQ28348.1 - 1.2e-20 73.4 0.0 1.9e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEQ28348.1 - 8.1e-11 41.6 0.0 1.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEQ28348.1 - 2e-05 23.8 0.0 6.6e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 KaiC ISG65-75 PF11727.3 EEQ28348.1 - 0.021 13.8 0.4 0.039 13.0 0.3 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein AAA_22 PF13401.1 EEQ28348.1 - 0.035 14.2 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RecA PF00154.16 EEQ28348.1 - 0.064 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DAO PF01266.19 EEQ28349.1 - 6e-47 160.2 0.1 7.3e-47 159.9 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ28349.1 - 7e-06 25.9 0.1 1.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEQ28349.1 - 0.00039 19.4 0.0 0.0017 17.3 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EEQ28349.1 - 0.00041 19.5 0.0 0.00063 18.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EEQ28349.1 - 0.0017 18.4 0.0 0.79 9.7 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEQ28349.1 - 0.0062 15.4 0.1 0.012 14.5 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EEQ28349.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EEQ28349.1 - 0.042 12.6 0.7 0.071 11.9 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain La PF05383.12 EEQ28350.1 - 3.7e-18 65.0 0.0 7.2e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EEQ28350.1 - 1.2e-05 24.8 0.0 4.2e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ28350.1 - 0.00014 21.7 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Chitin_synth_2 PF03142.10 EEQ28351.1 - 2.7e-23 82.1 5.3 5e-23 81.2 0.9 2.4 2 1 0 2 2 2 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EEQ28351.1 - 2.5e-17 63.4 0.0 4.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EEQ28351.1 - 5e-17 62.2 8.7 5e-17 62.2 6.1 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EEQ28351.1 - 0.0048 16.5 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 HSP70 PF00012.15 EEQ28352.1 - 8e-157 522.7 0.7 4.3e-139 464.1 0.1 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EEQ28352.1 - 2.5e-10 39.4 0.3 5.1e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EEQ28352.1 - 0.00028 20.7 0.7 0.12 12.1 0.1 3.4 3 1 0 3 3 3 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 EEQ28352.1 - 0.12 12.2 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EEQ28353.1 - 6.2e-74 248.2 0.7 1.1e-73 247.4 0.5 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEQ28353.1 - 2.2e-41 140.1 0.6 4.8e-41 139.0 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EEQ28353.1 - 0.002 17.7 0.1 0.26 10.9 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WLM PF08325.5 EEQ28354.1 - 4.4e-47 160.3 0.0 6.2e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EEQ28354.1 - 6.9e-05 22.7 0.1 0.0005 19.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 EEQ28354.1 - 0.0096 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Telomere_Sde2 PF13019.1 EEQ28354.1 - 0.082 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Telomere stability and silencing USP7_C2 PF14533.1 EEQ28354.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal PB1 PF00564.19 EEQ28354.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 PB1 domain Rad60-SLD PF11976.3 EEQ28354.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like LicD PF04991.8 EEQ28355.1 - 2.1e-36 125.9 3.2 4.8e-35 121.5 2.2 2.1 1 1 0 1 1 1 1 LicD family AcetylCoA_hyd_C PF13336.1 EEQ28355.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain zf-C4H2 PF10146.4 EEQ28356.1 - 0.039 13.9 0.8 0.064 13.2 0.6 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DASH_Ask1 PF08655.5 EEQ28357.1 - 2.7e-24 84.7 0.3 5.3e-24 83.8 0.2 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 RhoGAP PF00620.22 EEQ28358.1 - 1e-45 155.0 0.2 3.3e-45 153.4 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EEQ28358.1 - 3.9e-14 52.4 18.7 1.8e-09 37.4 2.0 2.4 2 0 0 2 2 2 2 LIM domain zinc_ribbon_2 PF13240.1 EEQ28358.1 - 0.89 9.1 0.0 0.89 9.1 0.0 4.1 3 1 2 5 5 5 0 zinc-ribbon domain APH PF01636.18 EEQ28360.1 - 0.00025 20.8 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family 4HBT PF03061.17 EEQ28362.1 - 1.6e-07 31.3 0.1 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EEQ28362.1 - 0.064 12.9 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Carn_acyltransf PF00755.15 EEQ28363.1 - 9.5e-167 555.6 0.0 9.1e-166 552.4 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase JmjC PF02373.17 EEQ28364.1 - 9.1e-38 129.0 1.3 1.7e-37 128.1 0.3 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 EEQ28364.1 - 7.7e-19 67.6 2.7 1.4e-18 66.7 1.9 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EEQ28364.1 - 1.8e-18 66.5 2.1 3e-18 65.8 1.5 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.12 EEQ28364.1 - 1.1e-14 53.6 0.4 2.7e-14 52.3 0.3 1.8 1 0 0 1 1 1 1 jmjN domain PhyH PF05721.8 EEQ28367.1 - 0.0014 18.7 0.0 0.0029 17.6 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Arteri_Gl PF00951.13 EEQ28371.1 - 0.16 11.5 2.0 0.28 10.7 1.4 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein LysM PF01476.15 EEQ28372.1 - 5.4e-08 32.6 0.0 0.00077 19.3 0.0 2.7 2 0 0 2 2 2 2 LysM domain AA_permease_2 PF13520.1 EEQ28373.1 - 2.1e-61 207.7 52.7 2.5e-61 207.5 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ28373.1 - 2.7e-31 108.4 47.8 3.5e-31 108.0 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease Cyclase PF04199.8 EEQ28374.1 - 1.3e-14 54.2 0.9 2.7e-14 53.2 0.5 1.6 1 1 0 1 1 1 1 Putative cyclase PEP_mutase PF13714.1 EEQ28375.1 - 8.4e-62 208.4 0.0 1e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MinE PF03776.9 EEQ28375.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE DHDPS PF00701.17 EEQ28377.1 - 2.2e-36 124.9 0.0 9.7e-35 119.5 0.0 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Ribonuc_L-PSP PF01042.16 EEQ28378.1 - 4e-39 133.1 0.1 4.5e-39 132.9 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP QRPTase_C PF01729.14 EEQ28378.1 - 0.023 14.2 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain D-ser_dehydrat PF14031.1 EEQ28379.1 - 7.4e-28 96.5 0.0 1.3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EEQ28379.1 - 1.9e-12 47.2 0.0 2.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Velvet PF11754.3 EEQ28381.1 - 2e-62 210.4 0.0 3.9e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 Velvet factor Hamartin PF04388.7 EEQ28381.1 - 4.9 5.7 7.1 6.9 5.2 4.9 1.2 1 0 0 1 1 1 0 Hamartin protein NP1-WLL PF11733.3 EEQ28382.1 - 0.12 12.6 2.8 0.2 11.9 1.9 1.4 1 1 0 1 1 1 0 Non-capsid protein NP1 PPTA PF01239.17 EEQ28383.1 - 0.0058 15.9 4.9 0.82 9.1 1.1 3.1 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat CDK2AP PF09806.4 EEQ28383.1 - 0.06 13.5 2.9 0.098 12.8 2.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Chorion_2 PF03964.10 EEQ28383.1 - 0.61 10.6 5.1 1.4 9.4 3.2 1.9 2 0 0 2 2 2 0 Chorion family 2 AA_permease_2 PF13520.1 EEQ28385.1 - 4.2e-40 137.5 53.8 5.4e-40 137.2 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ28385.1 - 6.9e-25 87.3 49.2 2.2e-24 85.6 34.1 1.6 1 1 0 1 1 1 1 Amino acid permease TRAM_LAG1_CLN8 PF03798.11 EEQ28386.1 - 7.1e-38 130.1 22.7 7.1e-38 130.1 15.7 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EEQ28386.1 - 5.4e-14 51.4 0.1 5.4e-14 51.4 0.1 2.0 2 0 0 2 2 2 1 TRAM1-like protein RRM_1 PF00076.17 EEQ28387.1 - 3e-15 55.5 0.0 6.9e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ28387.1 - 8.6e-11 41.6 0.0 1.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ28387.1 - 1.1e-07 31.5 0.1 2.3e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN PF06003.7 EEQ28388.1 - 1.6e-05 24.1 8.1 0.00015 20.9 2.3 2.7 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) APH PF01636.18 EEQ28389.1 - 4.1e-10 39.8 3.1 2.6e-09 37.1 0.3 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ28389.1 - 0.039 13.0 0.0 0.08 12.0 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase Thiolase_C PF02803.13 EEQ28390.1 - 1.4e-11 43.8 2.7 1.6e-10 40.4 0.0 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EEQ28390.1 - 4.4e-08 32.6 0.0 3.5e-06 26.5 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EEQ28390.1 - 6.3e-06 25.3 0.1 1.7e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EEQ28390.1 - 0.0075 15.7 0.1 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 EEQ28390.1 - 0.013 13.9 0.5 0.034 12.6 0.1 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) DUF3208 PF11482.3 EEQ28390.1 - 0.074 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) Mito_carr PF00153.22 EEQ28391.1 - 1.2e-38 130.7 5.9 3.8e-16 58.5 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein BRO1 PF03097.13 EEQ28392.1 - 5.4e-106 354.5 3.6 9.2e-106 353.7 0.0 2.7 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EEQ28392.1 - 8.6e-86 287.5 15.6 8.6e-86 287.5 10.8 2.3 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV zf-C4H2 PF10146.4 EEQ28392.1 - 1 9.3 13.0 0.03 14.3 2.3 3.0 1 1 2 3 3 3 0 Zinc finger-containing protein bZIP_2 PF07716.10 EEQ28393.1 - 4e-12 45.7 12.7 4e-12 45.7 8.8 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EEQ28393.1 - 1.5e-07 31.2 11.8 1.5e-07 31.2 8.2 1.6 2 0 0 2 2 2 1 bZIP transcription factor PRESAN PF09687.5 EEQ28393.1 - 0.059 13.4 0.1 0.096 12.7 0.1 1.3 1 0 0 1 1 1 0 Plasmodium RESA N-terminal V_ATPase_I PF01496.14 EEQ28393.1 - 0.089 10.6 1.6 0.12 10.2 1.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.4 EEQ28393.1 - 0.11 10.7 21.7 0.13 10.5 15.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EEQ28393.1 - 0.18 11.1 21.7 0.23 10.8 15.1 1.3 1 0 0 1 1 1 0 Vta1 like vMSA PF00695.14 EEQ28393.1 - 1.4 8.0 5.5 1.8 7.6 3.8 1.4 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus ORC6 PF05460.8 EEQ28394.1 - 1.6 7.7 5.2 2.2 7.2 3.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AICARFT_IMPCHas PF01808.13 EEQ28395.1 - 1.6e-109 365.8 0.0 2.3e-109 365.3 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EEQ28395.1 - 3.3e-24 84.6 0.0 6e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain FKBP_C PF00254.23 EEQ28399.1 - 5.1e-12 45.6 0.0 9.5e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-C2H2_4 PF13894.1 EEQ28399.1 - 0.091 13.1 12.5 0.79 10.2 0.5 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger DUF3580 PF12117.3 EEQ28400.1 - 0.0094 15.8 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3580) PAH PF02671.16 EEQ28402.1 - 1.2e-08 34.4 0.0 2.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat CENP-N PF05238.8 EEQ28403.1 - 5.7e-115 384.5 0.1 6.8e-115 384.3 0.1 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF1082 PF06449.6 EEQ28403.1 - 0.58 10.0 2.5 23 4.9 0.1 3.2 4 0 0 4 4 4 0 Mitochondrial domain of unknown function (DUF1082) zf-RING_2 PF13639.1 EEQ28404.1 - 9.5e-08 31.7 5.5 9.5e-08 31.7 3.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EEQ28404.1 - 1.1e-06 28.3 5.2 2.9e-06 27.0 1.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SWIM PF04434.12 EEQ28404.1 - 6.3e-05 22.3 0.4 0.00012 21.4 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.2 EEQ28404.1 - 0.0014 18.6 3.0 0.0014 18.6 2.1 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEQ28404.1 - 0.005 16.5 6.0 0.005 16.5 4.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 EEQ28404.1 - 0.0063 16.0 6.0 0.0063 16.0 4.1 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EEQ28404.1 - 0.011 15.6 10.5 0.022 14.7 4.8 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 EEQ28404.1 - 0.027 14.4 7.3 0.027 14.4 5.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EEQ28404.1 - 0.049 13.6 7.5 0.12 12.4 5.2 1.7 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EEQ28404.1 - 0.054 13.1 6.5 0.12 12.1 4.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 EEQ28404.1 - 0.22 11.2 7.3 0.052 13.2 2.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EEQ28404.1 - 0.42 10.3 6.9 0.23 11.2 1.8 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SCRL PF06876.7 EEQ28404.1 - 1.1 9.3 8.4 0.17 11.8 0.8 2.3 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein zf-RING-like PF08746.6 EEQ28404.1 - 1.3 9.1 7.0 0.6 10.1 2.6 2.1 2 0 0 2 2 2 0 RING-like domain zf-RING_UBOX PF13445.1 EEQ28404.1 - 3.4 7.4 6.0 0.93 9.2 1.7 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEQ28404.1 - 5 7.0 7.4 34 4.4 5.1 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF974 PF06159.8 EEQ28405.1 - 2.5e-69 233.4 0.0 3.1e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.16 EEQ28407.1 - 9.1e-57 191.7 0.1 2e-56 190.6 0.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EEQ28407.1 - 5.7e-20 71.1 0.2 1.2e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EEQ28407.1 - 3.4e-18 65.3 0.0 9.2e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 EEQ28407.1 - 0.00056 19.5 4.9 0.001 18.7 3.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EEQ28407.1 - 0.0024 17.8 4.9 0.0024 17.8 3.4 1.7 2 0 0 2 2 2 1 C1-like domain Vps39_2 PF10367.4 EEQ28407.1 - 0.072 13.2 1.0 0.15 12.2 0.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 C1_2 PF03107.11 EEQ28407.1 - 1.1 9.4 6.4 2.2 8.4 4.4 1.6 1 0 0 1 1 1 0 C1 domain PHD PF00628.24 EEQ28407.1 - 1.4 8.6 8.1 0.98 9.1 4.2 1.8 1 1 1 2 2 2 0 PHD-finger RTA1 PF04479.8 EEQ28408.1 - 1e-53 182.1 13.9 1e-53 182.1 9.6 1.7 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.3 EEQ28409.1 - 0.017 13.7 0.7 0.027 13.0 0.2 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain Ninjurin PF04923.7 EEQ28410.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Ninjurin Ank PF00023.25 EEQ28412.1 - 2.8e-06 26.8 0.0 0.0083 15.8 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EEQ28412.1 - 1.1e-05 25.7 0.0 0.00035 20.8 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ28412.1 - 0.001 19.2 0.2 0.019 15.2 0.2 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ28412.1 - 0.0027 17.8 0.0 0.56 10.6 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EEQ28412.1 - 0.14 12.6 0.1 7.7 7.1 0.1 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) HATPase_c_3 PF13589.1 EEQ28413.1 - 5.7e-20 71.3 0.0 1.1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EEQ28413.1 - 1.7e-12 47.1 0.1 7.3e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EEQ28413.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RasGEF PF00617.14 EEQ28414.1 - 5.5e-56 189.2 0.6 1.1e-55 188.3 0.4 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEQ28414.1 - 5e-17 61.9 0.0 1.7e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EEQ28414.1 - 1.5e-06 27.6 0.0 3.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ28414.1 - 3.5e-05 23.1 0.0 7.8e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain GHMP_kinases_N PF00288.21 EEQ28416.1 - 5e-14 52.1 0.0 1.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEQ28416.1 - 0.00016 21.7 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Med5 PF08689.5 EEQ28417.1 - 9.3e-279 927.3 0.0 1.3e-278 926.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 ELFV_dehydrog PF00208.16 EEQ28420.1 - 2.6e-80 269.5 1.4 3.2e-80 269.2 1.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EEQ28420.1 - 1.4e-37 128.2 0.0 3.8e-37 126.7 0.0 1.8 1 1 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DPBB_1 PF03330.13 EEQ28421.1 - 0.00065 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel MFS_1 PF07690.11 EEQ28423.1 - 1.9e-09 36.7 33.8 1.9e-09 36.7 23.4 3.7 2 2 1 3 3 3 2 Major Facilitator Superfamily Chloroa_b-bind PF00504.16 EEQ28423.1 - 0.12 12.5 0.9 0.37 11.0 0.1 2.3 2 0 0 2 2 2 0 Chlorophyll A-B binding protein Ribonuc_red_lgC PF02867.10 EEQ28424.1 - 3.7e-214 712.2 0.0 6e-214 711.5 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EEQ28424.1 - 2.6e-25 88.0 0.0 5.8e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EEQ28424.1 - 7.8e-17 61.4 0.2 3.3e-16 59.4 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain Sporozoite_P67 PF05642.6 EEQ28425.1 - 0.17 9.7 7.9 0.15 9.8 5.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF515 PF04415.7 EEQ28425.1 - 1.5 7.0 9.5 1.8 6.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AAA_17 PF13207.1 EEQ28426.1 - 2.1e-06 28.5 0.4 2e-05 25.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EEQ28426.1 - 0.00014 21.4 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EEQ28426.1 - 0.0002 21.6 0.2 0.0078 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EEQ28426.1 - 0.00027 19.8 0.0 0.0004 19.3 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 EEQ28426.1 - 0.0011 18.1 0.6 0.0088 15.1 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EEQ28426.1 - 0.0011 18.8 0.2 0.035 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ28426.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EEQ28426.1 - 0.0015 18.7 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEQ28426.1 - 0.004 16.8 0.1 0.0081 15.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EEQ28426.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EEQ28426.1 - 0.028 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Thymidylate_kin PF02223.12 EEQ28426.1 - 0.035 13.4 0.0 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase APS_kinase PF01583.15 EEQ28426.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase cobW PF02492.14 EEQ28426.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 EEQ28426.1 - 0.1 11.5 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain DUF2075 PF09848.4 EEQ28426.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EEQ28426.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EEQ28426.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.13 EEQ28426.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Adhesin_P1 PF03257.8 EEQ28427.1 - 0.054 13.7 4.0 0.072 13.4 2.8 1.2 1 0 0 1 1 1 0 Mycoplasma adhesin P1 APC_CDC26 PF10471.4 EEQ28427.1 - 0.093 13.4 6.1 0.16 12.7 4.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Apc15p PF05841.6 EEQ28427.1 - 0.31 11.7 6.1 0.4 11.4 4.2 1.2 1 0 0 1 1 1 0 Apc15p protein Mur_ligase_M PF08245.7 EEQ28428.1 - 4.2e-08 33.4 3.5 2.1e-06 27.9 0.9 2.6 2 1 0 2 2 2 2 Mur ligase middle domain Pkinase PF00069.20 EEQ28429.1 - 3.6e-62 209.8 0.0 1.1e-61 208.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28429.1 - 6.8e-44 149.8 0.0 1.8e-43 148.5 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ28429.1 - 0.0048 15.8 0.0 0.015 14.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like HEAT PF02985.17 EEQ28429.1 - 0.053 13.6 0.5 1.1e+02 3.2 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat Peptidase_M24 PF00557.19 EEQ28430.1 - 1.6e-46 158.4 0.1 2e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 FAA_hydrolase PF01557.13 EEQ28430.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NST1 PF13945.1 EEQ28430.1 - 0.059 13.4 4.1 0.091 12.8 2.9 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator TATR PF03430.8 EEQ28430.1 - 0.11 11.0 3.9 0.15 10.6 2.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator CDC45 PF02724.9 EEQ28430.1 - 1 7.2 5.8 1.4 6.8 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 EEQ28430.1 - 9.6 6.5 9.3 23 5.3 6.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DnaJ PF00226.26 EEQ28431.1 - 2.1e-23 81.8 0.5 3.6e-23 81.0 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 EEQ28432.1 - 4.9e-70 235.9 2.9 5.5e-70 235.7 2.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin KdpC PF02669.10 EEQ28432.1 - 0.042 13.5 0.6 0.073 12.7 0.4 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Asn_synthase PF00733.16 EEQ28433.1 - 7.7e-66 222.1 0.0 1e-65 221.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EEQ28433.1 - 6.7e-33 113.0 0.0 1.2e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EEQ28433.1 - 9e-21 74.2 0.0 1.7e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EEQ28433.1 - 6.1e-08 32.1 0.1 1.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EEQ28433.1 - 0.0008 18.3 0.0 0.0033 16.3 0.0 1.8 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EEQ28433.1 - 0.0072 15.0 0.0 1 8.0 0.0 2.6 1 1 2 3 3 3 2 Glutamine amidotransferases class-II UQ_con PF00179.21 EEQ28434.1 - 5.7e-42 142.4 0.0 1.2e-41 141.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme G-patch PF01585.18 EEQ28435.1 - 1.8e-11 43.6 0.7 4e-11 42.4 0.5 1.6 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EEQ28435.1 - 4.5e-06 26.4 0.1 9e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ28435.1 - 7.3e-05 22.3 0.1 0.00021 20.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ28435.1 - 0.0022 17.9 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 EEQ28436.1 - 1.6e-86 290.3 0.0 1.8e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ28436.1 - 4e-12 46.8 0.1 1.1e-11 45.4 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EEQ28436.1 - 0.0074 14.8 0.0 0.071 11.6 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Fungal_trans PF04082.13 EEQ28437.1 - 3.7e-20 71.9 1.7 6.7e-20 71.0 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 EEQ28438.1 - 1e-17 63.8 0.0 3.5e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Rad10 PF03834.9 EEQ28439.1 - 4.5e-31 106.3 0.0 7e-31 105.7 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EEQ28439.1 - 9.1e-06 25.7 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EEQ28439.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.17 EEQ28440.1 - 1.6e-60 200.6 0.0 4.7e-19 67.7 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ28440.1 - 1.8e-42 143.1 0.0 4e-13 49.1 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ28440.1 - 7.6e-22 76.9 0.0 1.1e-06 28.3 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEQ28440.1 - 0.00025 20.7 0.4 0.075 12.7 0.0 4.4 4 0 0 4 4 4 1 Limkain b1 CSD PF00313.17 EEQ28440.1 - 0.098 12.4 1.7 6.8 6.5 0.1 3.3 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain Cyt-b5 PF00173.23 EEQ28441.1 - 1.7e-08 34.1 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.16 EEQ28442.1 - 5.8e-99 331.5 34.2 7.1e-99 331.3 23.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ28442.1 - 2.2e-15 56.1 39.0 3.1e-15 55.6 27.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EEQ28442.1 - 0.028 14.1 1.1 0.028 14.1 0.8 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) Orai-1 PF07856.7 EEQ28442.1 - 0.095 12.2 12.7 0.028 13.9 4.5 2.3 2 0 0 2 2 2 0 Mediator of CRAC channel activity Cupin_8 PF13621.1 EEQ28443.1 - 1.8e-23 83.3 0.0 2.5e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EEQ28443.1 - 0.0011 18.2 0.0 0.0031 16.8 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 EEQ28443.1 - 0.013 15.6 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.6 EEQ28443.1 - 0.067 12.6 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Fungal_trans PF04082.13 EEQ28444.1 - 1.7e-18 66.4 0.0 3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PsbT PF01405.12 EEQ28444.1 - 0.37 10.4 3.2 0.87 9.2 2.2 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre T protein CK_II_beta PF01214.13 EEQ28445.1 - 1.1e-75 253.2 0.0 6e-75 250.8 0.0 1.9 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EEQ28445.1 - 0.0073 16.9 9.2 0.014 16.0 4.1 2.4 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Myc_N PF01056.13 EEQ28445.1 - 0.21 10.7 8.5 1.4 8.0 1.1 2.1 2 0 0 2 2 2 0 Myc amino-terminal region ATP-synt_E PF05680.7 EEQ28445.1 - 0.25 11.2 1.8 29 4.6 0.0 3.1 3 0 0 3 3 3 0 ATP synthase E chain Nucleoplasmin PF03066.10 EEQ28445.1 - 1.6 8.2 9.3 0.34 10.4 3.3 1.9 2 0 0 2 2 2 0 Nucleoplasmin bZIP_1 PF00170.16 EEQ28446.1 - 0.0066 16.3 6.3 0.01 15.7 4.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EEQ28446.1 - 0.038 14.2 1.4 0.058 13.6 0.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EEQ28446.1 - 0.055 13.3 5.8 0.087 12.6 4.0 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Aminotran_4 PF01063.14 EEQ28448.1 - 4.8e-30 104.7 0.0 7.6e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EEQ28449.1 - 1.6e-17 63.5 0.0 3.9e-17 62.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28449.1 - 7.4e-08 31.7 0.0 2.6e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase ParcG PF10274.4 EEQ28449.1 - 0.027 14.3 0.6 5.9 6.7 0.1 2.4 2 0 0 2 2 2 0 Parkin co-regulated protein Peptidase_M49 PF03571.10 EEQ28450.1 - 3.4e-232 771.4 0.0 4.3e-232 771.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF533 PF04391.7 EEQ28451.1 - 0.034 13.5 0.3 0.062 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) SNF5 PF04855.7 EEQ28453.1 - 1.2e-80 270.5 0.0 1.6e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EEQ28453.1 - 0.028 13.7 6.0 0.081 12.2 4.2 1.8 1 0 0 1 1 1 0 GATA zinc finger BHD_1 PF10403.4 EEQ28455.1 - 0.091 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 WD40 PF00400.27 EEQ28456.1 - 2.1e-48 160.5 27.1 3.6e-13 48.8 0.5 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EEQ28456.1 - 6.8e-06 25.8 13.8 0.011 15.5 2.1 3.8 2 2 3 5 5 5 2 Transcription factor IIIC subunit delta N-term Ank_2 PF12796.2 EEQ28457.1 - 1.4e-37 127.8 9.5 3e-11 43.5 0.0 4.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ28457.1 - 2.3e-26 91.6 7.1 1.3e-10 41.5 0.0 5.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EEQ28457.1 - 2.6e-22 77.4 10.4 0.00086 19.0 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat SPX PF03105.14 EEQ28457.1 - 2.7e-18 66.7 0.7 5.1e-18 65.8 0.5 1.5 1 0 0 1 1 1 1 SPX domain Ank_3 PF13606.1 EEQ28457.1 - 7.2e-16 56.7 9.5 0.0016 18.4 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat GDPD PF03009.12 EEQ28457.1 - 2.4e-13 50.1 0.0 5.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.1 EEQ28457.1 - 2e-11 43.7 11.4 0.009 16.2 0.0 6.6 2 1 4 7 7 7 6 Ankyrin repeats (many copies) MFS_1 PF07690.11 EEQ28460.1 - 8e-41 139.9 39.8 8e-41 139.9 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ28461.1 - 2e-102 343.1 21.6 1.1e-101 340.6 15.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ28461.1 - 6.5e-27 94.1 22.8 6.5e-27 94.1 15.8 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ28461.1 - 3.3e-06 25.5 5.0 5.9e-06 24.7 3.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PspC PF04024.7 EEQ28461.1 - 0.021 14.2 1.3 0.076 12.5 0.0 2.6 2 0 0 2 2 2 0 PspC domain Nucleos_tra2_N PF01773.15 EEQ28461.1 - 0.64 10.3 9.8 4.1 7.8 0.1 3.7 4 0 0 4 4 4 0 Na+ dependent nucleoside transporter N-terminus ABC_tran PF00005.22 EEQ28462.1 - 7.1e-47 159.1 0.6 6.6e-23 81.5 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EEQ28462.1 - 1.4e-21 76.1 7.2 1.4e-21 76.1 5.0 3.2 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 EEQ28462.1 - 2e-16 60.8 2.0 0.0007 19.6 0.0 5.1 6 0 0 6 6 6 3 AAA domain SMC_N PF02463.14 EEQ28462.1 - 2.4e-11 43.3 0.2 0.0055 15.9 0.0 4.5 4 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEQ28462.1 - 1.4e-08 35.6 0.2 0.01 16.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ28462.1 - 4.2e-06 26.6 0.0 0.065 13.1 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EEQ28462.1 - 5.1e-06 26.6 0.7 0.02 14.9 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EEQ28462.1 - 5.9e-06 26.4 0.0 0.037 14.1 0.0 3.0 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 EEQ28462.1 - 7.6e-06 25.2 0.1 0.051 12.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EEQ28462.1 - 1.1e-05 25.8 0.2 0.057 13.9 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_29 PF13555.1 EEQ28462.1 - 1.3e-05 24.6 0.2 0.16 11.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 EEQ28462.1 - 5.2e-05 23.1 0.1 0.49 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEQ28462.1 - 7.1e-05 23.1 5.5 0.25 11.6 0.0 4.0 5 0 0 5 5 3 2 AAA domain AAA_15 PF13175.1 EEQ28462.1 - 0.00011 21.4 11.4 0.81 8.6 0.0 5.3 4 2 1 5 5 5 2 AAA ATPase domain MobB PF03205.9 EEQ28462.1 - 0.00014 21.6 0.1 0.63 9.7 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EEQ28462.1 - 0.00025 21.0 1.8 0.37 10.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.18 EEQ28462.1 - 0.00025 20.9 3.7 0.48 10.2 0.0 3.9 4 0 0 4 4 4 1 Dynamin family AAA_23 PF13476.1 EEQ28462.1 - 0.00034 20.9 18.9 0.021 15.1 0.0 4.9 5 0 0 5 5 5 2 AAA domain AAA_10 PF12846.2 EEQ28462.1 - 0.00041 19.8 0.1 1.3 8.3 0.0 3.5 3 0 0 3 3 3 1 AAA-like domain AAA_30 PF13604.1 EEQ28462.1 - 0.00072 19.1 0.0 0.03 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEQ28462.1 - 0.0014 18.2 0.2 1.1 8.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 EEQ28462.1 - 0.0023 18.1 0.1 1 9.5 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEQ28462.1 - 0.0043 16.1 1.6 0.33 10.0 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin ArgK PF03308.11 EEQ28462.1 - 0.0048 15.7 3.6 1.1 8.0 0.1 2.9 3 0 0 3 3 3 2 ArgK protein SbcCD_C PF13558.1 EEQ28462.1 - 0.0071 16.2 0.2 5 7.1 0.1 3.5 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EEQ28462.1 - 0.012 15.5 0.7 6.3 6.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.17 EEQ28462.1 - 0.013 15.7 0.0 6.4 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 EEQ28462.1 - 0.019 14.6 0.1 2.1 8.0 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 EEQ28462.1 - 0.019 14.5 0.1 4.5 6.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EEQ28462.1 - 0.031 13.7 0.5 2.6 7.4 0.3 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EEQ28462.1 - 0.044 13.2 0.1 9.3 5.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EEQ28462.1 - 0.059 13.1 0.3 14 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Arf PF00025.16 EEQ28462.1 - 0.061 12.5 0.1 1.6 7.9 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family ATP-synt_ab PF00006.20 EEQ28462.1 - 0.071 12.5 0.0 4.4 6.7 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.16 EEQ28462.1 - 0.11 11.7 0.5 43 3.1 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF2346 PF09803.4 EEQ28462.1 - 7.6 6.4 9.2 0.36 10.7 1.5 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) DUF1279 PF06916.8 EEQ28465.1 - 5.2e-28 97.1 0.0 7.2e-28 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L3 PF00297.17 EEQ28466.1 - 6.3e-37 127.4 2.2 5.5e-36 124.3 1.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 EEQ28467.1 - 2.8e-42 142.9 0.0 3.4e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4064 PF13273.1 EEQ28468.1 - 0.11 12.6 0.3 1.8 8.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.1 EEQ28468.1 - 1.8 7.9 4.6 17 4.7 3.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) JmjC PF02373.17 EEQ28469.1 - 2.3e-08 34.2 1.1 4.8e-07 30.0 0.8 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EEQ28469.1 - 5e-05 23.3 6.9 0.00013 22.0 4.8 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EEQ28469.1 - 0.0084 15.5 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Flavoprotein PF02441.14 EEQ28470.1 - 4.4e-38 129.8 0.1 6e-38 129.4 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.19 EEQ28471.1 - 5.2e-15 55.1 0.0 8.3e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Fib_alpha PF08702.5 EEQ28472.1 - 0.41 10.7 11.3 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CTP_transf_2 PF01467.21 EEQ28473.1 - 2.4e-18 66.6 0.2 6e-16 58.8 0.0 3.0 3 1 0 3 3 3 2 Cytidylyltransferase PRELI PF04707.9 EEQ28475.1 - 2.7e-44 150.4 0.4 3.2e-44 150.2 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family PXA PF02194.10 EEQ28476.1 - 4.8e-35 120.8 0.0 3e-34 118.2 0.0 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EEQ28476.1 - 2.4e-18 66.2 0.0 6.4e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EEQ28476.1 - 8e-10 38.5 0.0 2.1e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.22 EEQ28477.1 - 7.5e-74 243.5 0.9 1.4e-24 85.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EEQ28479.1 - 3e-12 45.9 0.0 4.1e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ28479.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ28479.1 - 3e-07 30.3 0.0 4.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ28479.1 - 0.0019 17.9 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sedlin_N PF04628.8 EEQ28480.1 - 6.6e-27 93.9 0.0 8.2e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EEQ28480.1 - 0.016 14.9 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Sybindin-like family MLIP PF15274.1 EEQ28480.1 - 0.076 12.5 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Muscular LMNA-interacting protein Ribosomal_L18e PF00828.14 EEQ28481.1 - 2.4e-18 66.7 0.1 3.4e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aldedh PF00171.17 EEQ28482.1 - 1.2e-09 37.0 7.1 4.7e-09 35.1 3.1 2.5 1 1 1 2 2 2 2 Aldehyde dehydrogenase family PCI PF01399.22 EEQ28483.1 - 0.0003 21.0 0.0 0.00074 19.8 0.0 1.7 1 0 0 1 1 1 1 PCI domain NifU_N PF01592.11 EEQ28484.1 - 2.2e-39 134.2 0.0 3.1e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain Oxidored_q6 PF01058.17 EEQ28485.1 - 3e-22 78.6 0.0 4.4e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit UDG PF03167.14 EEQ28486.1 - 9.5e-26 90.0 0.1 1.6e-25 89.3 0.1 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ELL PF10390.4 EEQ28487.1 - 5.8 6.0 10.4 5.9 6.0 7.2 1.0 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL COX16 PF14138.1 EEQ28487.1 - 7.7 6.7 10.0 9.8 6.4 6.9 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 UCH PF00443.24 EEQ28489.1 - 8.6e-44 149.6 0.0 1.7e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEQ28489.1 - 4.7e-24 84.2 15.5 1.4e-19 69.9 0.9 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EEQ28489.1 - 1.5e-17 63.9 0.0 4.2e-12 46.1 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EEQ28489.1 - 3.4e-13 48.9 0.0 3.6e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 EEQ28489.1 - 0.025 14.0 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain FtsJ PF01728.14 EEQ28490.1 - 1.3e-59 201.2 0.0 1.5e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EEQ28490.1 - 0.00013 21.6 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ28490.1 - 0.00054 19.7 0.0 0.001 18.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ28490.1 - 0.0098 16.4 0.0 0.02 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ThiF PF00899.16 EEQ28491.1 - 1.6e-26 92.7 0.0 2.8e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EEQ28491.1 - 0.0038 17.3 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EEQ28491.1 - 0.18 11.2 0.0 0.55 9.6 0.0 1.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA dCMP_cyt_deam_1 PF00383.17 EEQ28492.1 - 4e-26 90.6 2.4 6.6e-26 89.9 1.7 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region CoaE PF01121.15 EEQ28492.1 - 0.043 13.1 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_17 PF13207.1 EEQ28492.1 - 0.052 14.3 0.0 0.13 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ28492.1 - 0.17 12.2 0.0 0.59 10.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain His_biosynth PF00977.16 EEQ28493.1 - 1.5e-45 155.2 0.3 6.1e-45 153.2 0.2 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EEQ28493.1 - 5.7e-31 107.4 0.0 8.9e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EEQ28493.1 - 1.3e-09 37.9 0.0 3.3e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EEQ28493.1 - 2.1e-09 37.1 0.0 5.1e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.12 EEQ28493.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 DNA_pol_E_B PF04042.11 EEQ28494.1 - 1.2e-47 161.9 0.1 1.7e-47 161.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.4 EEQ28495.1 - 3.5e-18 64.5 2.6 7.6e-16 57.0 0.3 2.8 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.1 EEQ28495.1 - 2.3e-09 37.0 1.6 0.0013 18.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ28495.1 - 4e-07 29.5 5.9 0.00011 21.7 0.3 3.0 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 EEQ28495.1 - 0.001 19.6 0.4 0.001 19.6 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EEQ28495.1 - 0.047 13.5 3.3 0.31 10.9 0.8 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 EEQ28495.1 - 2.4 7.9 4.8 2.3 7.9 1.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Yippee-Mis18 PF03226.9 EEQ28496.1 - 6.1e-22 77.4 0.1 8.6e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly BNIP3 PF06553.7 EEQ28496.1 - 0.013 14.9 0.3 0.018 14.4 0.2 1.2 1 0 0 1 1 1 0 BNIP3 RIG-I_C-RD PF11648.3 EEQ28496.1 - 0.031 14.1 0.6 0.21 11.4 0.4 2.0 1 1 0 1 1 1 0 C-terminal domain of RIG-I Thioredoxin PF00085.15 EEQ28497.1 - 2.9e-66 219.6 7.5 2.6e-31 107.3 0.1 4.5 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 EEQ28497.1 - 3.6e-53 180.1 5.4 1.5e-40 139.0 0.6 3.6 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EEQ28497.1 - 4.1e-11 42.7 0.1 8e-05 22.5 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EEQ28497.1 - 8.3e-11 42.0 4.7 0.0001 22.5 0.1 4.4 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEQ28497.1 - 5.1e-10 39.3 0.2 0.0018 18.3 0.0 4.2 4 1 1 5 5 5 2 Thioredoxin-like Calsequestrin PF01216.12 EEQ28497.1 - 4.2e-08 32.3 4.4 2.1e-07 30.0 3.1 2.1 1 1 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.16 EEQ28497.1 - 2.3e-06 27.3 0.4 0.015 14.9 0.1 3.0 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 EEQ28497.1 - 1.8e-05 24.6 0.6 1.4 8.8 0.0 4.5 4 0 0 4 4 4 1 ERp29, N-terminal domain Redoxin PF08534.5 EEQ28497.1 - 9e-05 22.0 1.0 0.2 11.1 0.0 3.1 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.1 EEQ28497.1 - 0.19 11.7 5.3 3.6 7.5 0.0 3.8 4 0 0 4 4 4 0 Thioredoxin Med14 PF08638.6 EEQ28498.1 - 2.8e-51 173.5 0.0 6e-51 172.4 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 DWNN PF08783.6 EEQ28499.1 - 4.5e-33 113.0 0.1 9.2e-33 112.0 0.1 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EEQ28499.1 - 1.9e-05 24.0 7.0 6e-05 22.4 4.8 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EEQ28499.1 - 0.0012 18.6 1.5 0.0012 18.6 1.0 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 EEQ28499.1 - 0.023 14.4 0.2 0.066 12.9 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF1272 PF06906.6 EEQ28499.1 - 0.049 13.4 3.6 0.13 12.0 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FYVE_2 PF02318.11 EEQ28499.1 - 0.17 11.8 1.7 0.4 10.6 1.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.1 EEQ28499.1 - 0.8 9.6 6.9 2.3 8.1 4.8 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EEQ28499.1 - 1.7 8.4 8.0 3.8 7.2 5.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ28499.1 - 3 7.6 9.8 0.21 11.3 3.0 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ28499.1 - 4.8 7.3 13.1 0.44 10.6 4.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Nucleoporin_C PF03177.9 EEQ28500.1 - 9.1e-110 367.8 1.3 1.2e-109 367.5 0.9 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EEQ28500.1 - 3.3e-49 167.7 0.3 4.7e-49 167.2 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like HABP4_PAI-RBP1 PF04774.10 EEQ28501.1 - 0.00017 22.0 1.5 0.00028 21.3 1.0 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family OST3_OST6 PF04756.8 EEQ28502.1 - 2.3e-23 82.5 1.4 3.3e-23 82.0 1.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EEQ28502.1 - 0.00065 19.3 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin GAS PF13851.1 EEQ28503.1 - 0.017 14.3 15.0 0.051 12.7 10.4 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Filament PF00038.16 EEQ28503.1 - 0.08 12.3 18.4 0.075 12.4 6.7 2.4 1 1 0 2 2 2 0 Intermediate filament protein HALZ PF02183.13 EEQ28503.1 - 1.8 8.3 7.3 9.8 5.9 0.1 3.7 1 1 2 3 3 3 0 Homeobox associated leucine zipper KLRAQ PF10205.4 EEQ28503.1 - 2 8.4 20.0 1.9 8.5 2.3 3.5 2 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein IncA PF04156.9 EEQ28503.1 - 8.6 5.8 25.2 11 5.6 7.0 2.3 1 1 1 2 2 2 0 IncA protein Complex1_LYR PF05347.10 EEQ28504.1 - 1.5e-06 27.9 0.1 2.4e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ28504.1 - 0.00044 20.3 0.5 0.00073 19.7 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_6 PF14599.1 EEQ28505.1 - 2.8e-25 87.8 0.6 2.8e-25 87.8 0.4 3.6 3 1 2 5 5 5 1 Zinc-ribbon zf-CHY PF05495.7 EEQ28505.1 - 7.5e-15 54.8 16.6 7.5e-15 54.8 11.5 4.7 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EEQ28505.1 - 2.1e-08 33.8 8.2 2.1e-08 33.8 5.7 4.6 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ28505.1 - 2.2e-07 30.7 6.1 2.2e-07 30.7 4.2 5.1 3 3 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ28505.1 - 2.9e-07 30.0 9.2 2.9e-07 30.0 6.4 5.6 3 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ28505.1 - 6.8e-06 25.7 8.6 6.8e-06 25.7 5.9 6.9 4 3 1 5 5 5 1 zinc-RING finger domain Prok-RING_1 PF14446.1 EEQ28505.1 - 0.0011 18.6 1.5 0.0011 18.6 1.0 6.5 5 2 1 6 6 6 1 Prokaryotic RING finger family 1 Rrn6 PF10214.4 EEQ28506.1 - 7.9e-108 361.5 0.0 9.8e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Big_3_2 PF12245.3 EEQ28506.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Spindle_Spc25 PF08234.7 EEQ28507.1 - 5.4e-23 80.7 0.1 3e-22 78.4 0.0 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Bacillus_HBL PF05791.6 EEQ28507.1 - 0.053 12.8 7.5 0.077 12.3 5.2 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2450 PF10475.4 EEQ28507.1 - 0.11 11.4 9.5 0.15 10.9 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DUF3523 PF12037.3 EEQ28507.1 - 0.21 10.5 15.9 0.28 10.1 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF334 PF03904.8 EEQ28507.1 - 0.32 10.2 8.6 0.45 9.8 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Atg14 PF10186.4 EEQ28507.1 - 1.5 7.6 15.5 2.1 7.1 10.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 EEQ28507.1 - 2.7 6.3 7.9 3.1 6.1 5.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cortex-I_coil PF09304.5 EEQ28507.1 - 4 7.5 18.5 6.3 6.8 4.3 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 EEQ28507.1 - 5.2 4.8 8.4 14 3.4 5.9 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 EEQ28508.1 - 2e-20 71.8 8.3 0.0034 17.1 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Ribosomal_L32p PF01783.18 EEQ28508.1 - 4.3e-12 46.0 5.9 6.9e-12 45.3 4.1 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.1 EEQ28508.1 - 0.0059 15.7 0.8 0.012 14.7 0.6 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EEQ28508.1 - 0.039 13.7 0.5 0.08 12.7 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 EEQ28508.1 - 0.065 13.0 0.3 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbons Septin PF00735.13 EEQ28509.1 - 8.1e-112 372.8 0.4 9.6e-112 372.5 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EEQ28509.1 - 5.9e-07 29.4 0.0 9.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EEQ28509.1 - 3.9e-06 26.1 0.0 6.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EEQ28509.1 - 3.4e-05 23.0 0.0 6.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EEQ28509.1 - 0.00033 20.5 0.5 0.77 9.5 0.1 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EEQ28509.1 - 0.00093 18.6 0.4 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EEQ28509.1 - 0.0046 16.4 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 EEQ28509.1 - 0.0076 16.5 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEQ28509.1 - 0.0088 16.3 0.2 0.02 15.2 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EEQ28509.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EEQ28509.1 - 0.015 14.1 0.1 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EEQ28509.1 - 0.021 13.7 0.1 0.067 12.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.1 EEQ28509.1 - 0.045 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EEQ28509.1 - 0.052 13.0 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 EEQ28509.1 - 0.052 12.6 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.2 EEQ28509.1 - 0.1 11.6 0.0 13 4.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 AAA_29 PF13555.1 EEQ28509.1 - 0.13 11.8 0.1 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 EEQ28510.1 - 8e-60 201.4 0.0 2.3e-47 160.8 0.0 2.0 1 1 1 2 2 2 2 Guanylate kinase AAA_16 PF13191.1 EEQ28510.1 - 3.2e-06 27.2 0.2 1.5e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EEQ28510.1 - 6.1e-06 27.0 0.3 5.2e-05 24.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ28510.1 - 1.1e-05 25.6 0.6 0.0002 21.6 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ28510.1 - 1.2e-05 25.4 0.1 5.8e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEQ28510.1 - 3.4e-05 23.7 0.5 0.00067 19.5 0.4 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EEQ28510.1 - 0.00014 21.7 0.0 0.00029 20.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEQ28510.1 - 0.00031 19.9 0.0 0.00073 18.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_30 PF13604.1 EEQ28510.1 - 0.00091 18.8 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEQ28510.1 - 0.00096 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 EEQ28510.1 - 0.0011 18.9 0.1 0.0038 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ28510.1 - 0.0015 18.2 0.2 0.0042 16.8 0.0 1.9 2 1 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EEQ28510.1 - 0.0024 17.7 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEQ28510.1 - 0.0056 16.3 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 EEQ28510.1 - 0.0063 16.0 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2075 PF09848.4 EEQ28510.1 - 0.0079 15.2 0.1 0.059 12.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EEQ28510.1 - 0.0087 16.2 0.1 0.096 12.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EEQ28510.1 - 0.0096 16.0 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Miro PF08477.8 EEQ28510.1 - 0.012 16.0 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 EEQ28510.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 EEQ28510.1 - 0.019 13.8 0.0 0.043 12.6 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.9 EEQ28510.1 - 0.022 14.5 0.1 0.12 12.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EEQ28510.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EEQ28510.1 - 0.034 13.5 0.2 0.22 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EEQ28510.1 - 0.038 14.3 0.1 0.099 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EEQ28510.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EEQ28510.1 - 0.048 13.1 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1895 PF08988.5 EEQ28510.1 - 0.067 13.2 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) AAA_24 PF13479.1 EEQ28510.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EEQ28510.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.1 EEQ28510.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain GRAB PF10375.4 EEQ28511.1 - 2e-07 30.3 0.3 4.4e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EEQ28511.1 - 0.00054 19.2 15.0 0.0044 16.2 3.9 2.5 1 1 2 3 3 3 3 Reovirus sigma C capsid protein DUF3921 PF13060.1 EEQ28511.1 - 0.02 14.7 0.1 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) DUF4055 PF13264.1 EEQ28511.1 - 2.1 8.4 18.4 1.1 9.3 2.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4055) FliJ PF02050.11 EEQ28511.1 - 4.4 7.3 45.5 1.4 8.9 12.1 3.7 1 1 1 3 3 3 0 Flagellar FliJ protein DUF2576 PF10845.3 EEQ28511.1 - 4.8 6.4 5.9 8.3 5.6 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) DUF3390 PF11870.3 EEQ28513.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) DAO PF01266.19 EEQ28515.1 - 1.3e-47 162.4 0.0 1.8e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EEQ28515.1 - 8.3e-09 35.0 0.1 1.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ28515.1 - 5.5e-08 32.0 0.1 1.3e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEQ28515.1 - 0.00049 20.0 0.1 0.0014 18.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEQ28515.1 - 0.0012 18.5 0.2 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EEQ28515.1 - 0.0029 16.5 0.2 0.023 13.5 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EEQ28515.1 - 0.012 15.6 0.1 0.037 14.0 0.1 1.9 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEQ28515.1 - 0.016 14.1 0.0 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EEQ28515.1 - 0.031 14.6 0.2 0.11 12.8 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ28515.1 - 0.034 12.6 0.5 0.056 11.9 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EEQ28515.1 - 0.056 12.4 0.1 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_10 PF13460.1 EEQ28515.1 - 0.09 12.7 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 EEQ28515.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus p450 PF00067.17 EEQ28516.1 - 1e-64 218.8 0.0 1.1e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DASH_Dad2 PF08654.5 EEQ28517.1 - 2.5e-12 46.6 5.4 4.3e-11 42.7 1.0 2.1 1 1 1 2 2 2 2 DASH complex subunit Dad2 Herpes_UL25 PF01499.11 EEQ28517.1 - 0.0013 17.1 0.9 0.0014 17.0 0.6 1.0 1 0 0 1 1 1 1 Herpesvirus UL25 family Herpes_UL6 PF01763.11 EEQ28517.1 - 0.037 12.2 0.3 0.044 11.9 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Seryl_tRNA_N PF02403.17 EEQ28517.1 - 0.063 13.2 0.2 0.063 13.2 0.1 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FliD_N PF02465.13 EEQ28517.1 - 0.088 13.1 4.3 0.13 12.6 3.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus APG6 PF04111.7 EEQ28517.1 - 0.11 11.5 0.2 0.12 11.4 0.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 NPV_P10 PF05531.7 EEQ28517.1 - 0.11 12.7 0.6 0.15 12.2 0.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3138 PF11336.3 EEQ28517.1 - 0.16 10.0 2.6 0.2 9.8 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ADIP PF11559.3 EEQ28517.1 - 0.23 11.3 2.9 0.31 10.9 2.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EEQ28517.1 - 0.87 9.4 5.7 0.42 10.4 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2570 PF10828.3 EEQ28517.1 - 1.5 8.4 5.0 7.4 6.2 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Shugoshin_N PF07558.6 EEQ28518.1 - 7.8e-16 57.5 1.4 1.7e-15 56.4 1.0 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EEQ28518.1 - 1.6e-09 37.0 6.8 1.6e-09 37.0 4.7 3.0 3 0 0 3 3 3 1 Shugoshin C terminus DUF4362 PF14275.1 EEQ28518.1 - 0.0068 16.4 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4362) PPI_Ypi1 PF07491.6 EEQ28519.1 - 4.3e-23 80.7 8.5 2.6e-22 78.2 5.9 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor RNA_pol_3_Rpc31 PF11705.3 EEQ28519.1 - 0.029 14.3 0.9 0.036 14.0 0.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.7 EEQ28519.1 - 0.13 11.9 2.7 0.17 11.5 1.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ALAD PF00490.16 EEQ28520.1 - 1.1e-118 395.8 0.0 1.2e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Hexapep PF00132.19 EEQ28521.1 - 3.7e-14 51.5 5.2 4e-08 32.3 0.5 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EEQ28521.1 - 2.3e-12 46.7 0.0 5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 EEQ28521.1 - 3.3e-10 39.6 8.6 5.9e-10 38.8 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.1 EEQ28521.1 - 5.3e-09 35.4 4.5 2e-06 27.2 0.4 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase FAD_binding_3 PF01494.14 EEQ28523.1 - 8.3e-20 71.1 0.0 1.3e-18 67.2 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEQ28523.1 - 9.9e-09 34.5 1.6 2.2e-05 23.5 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ28523.1 - 1.4e-06 28.2 1.9 4e-06 26.7 1.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ28523.1 - 8.2e-06 25.8 0.3 0.00028 20.8 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ28523.1 - 1.4e-05 24.1 5.7 2.5e-05 23.3 4.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EEQ28523.1 - 0.00015 20.3 0.8 0.0052 15.3 1.6 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EEQ28523.1 - 0.00032 19.6 1.6 0.00043 19.2 1.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EEQ28523.1 - 0.00045 20.5 2.1 0.018 15.4 1.6 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEQ28523.1 - 0.0014 17.7 4.3 0.0022 17.1 2.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEQ28523.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ28523.1 - 0.0017 17.4 0.8 0.0029 16.7 0.6 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EEQ28523.1 - 0.0055 15.3 1.2 0.95 8.0 1.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EEQ28523.1 - 0.02 13.8 0.8 2.8 6.7 1.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EEQ28523.1 - 0.033 13.8 3.0 0.058 13.0 2.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EEQ28523.1 - 0.15 11.7 1.0 0.25 11.0 0.7 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EEQ28523.1 - 0.18 11.1 1.0 0.3 10.4 0.7 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CRM1_C PF08767.6 EEQ28524.1 - 4.5e-120 400.3 5.0 4.5e-120 400.3 3.5 3.5 3 2 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 EEQ28524.1 - 7.1e-42 142.8 6.7 7.1e-42 142.8 4.6 3.1 3 1 0 3 3 3 1 Exportin 1-like protein CIAPIN1 PF05093.8 EEQ28525.1 - 9.3e-36 121.9 3.9 1.4e-35 121.3 2.7 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Rft-1 PF04506.8 EEQ28526.1 - 2.4e-83 280.4 12.5 2.8e-83 280.1 8.6 1.0 1 0 0 1 1 1 1 Rft protein Rep_fac-A_C PF08646.5 EEQ28527.1 - 7.2e-47 158.7 5.9 6e-45 152.5 2.4 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EEQ28527.1 - 7.5e-21 73.8 0.0 1.6e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EEQ28527.1 - 3.4e-13 49.2 0.3 1.2e-08 34.6 0.0 4.2 3 1 1 4 4 4 3 OB-fold nucleic acid binding domain DUF223 PF02721.9 EEQ28527.1 - 0.032 14.3 0.5 0.27 11.3 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF223 DUF2293 PF10056.4 EEQ28528.1 - 1.9e-27 95.0 0.2 5.6e-27 93.5 0.1 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) MHYT PF03707.11 EEQ28529.1 - 1.3e-08 34.7 19.2 2.7e-06 27.4 1.4 3.9 4 0 0 4 4 4 2 Bacterial signalling protein N terminal repeat HMA PF00403.21 EEQ28530.1 - 5.4e-15 55.2 0.9 6.5e-15 55.0 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF1280 PF06918.9 EEQ28530.1 - 0.017 14.3 0.2 0.019 14.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) FAD_binding_4 PF01565.18 EEQ28530.1 - 0.055 12.9 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Tcp11 PF05794.8 EEQ28531.1 - 3.5e-49 167.7 0.2 2e-48 165.2 0.1 2.0 1 1 0 1 1 1 1 T-complex protein 11 PXA PF02194.10 EEQ28532.1 - 3.9e-47 160.2 0.8 1.1e-46 158.6 0.0 2.1 3 0 0 3 3 3 1 PXA domain DUF1670 PF07900.6 EEQ28532.1 - 0.018 14.2 0.0 0.062 12.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1670) AP_endonuc_2 PF01261.19 EEQ28532.1 - 0.058 12.6 0.2 0.68 9.1 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Nexin_C PF08628.7 EEQ28533.1 - 4.8e-29 100.7 0.5 1e-28 99.7 0.0 1.8 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EEQ28533.1 - 3.5e-20 71.8 0.1 6.7e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 PX domain DUF3770 PF12603.3 EEQ28533.1 - 0.002 17.2 0.2 0.0036 16.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3770) WD40 PF00400.27 EEQ28535.1 - 4.8e-27 92.8 5.1 2.9e-07 30.1 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat tRNA-synt_1g PF09334.6 EEQ28536.1 - 1.5e-141 471.6 0.0 2e-141 471.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEQ28536.1 - 2.4e-08 32.4 0.1 2.7e-05 22.3 0.0 3.6 3 1 1 4 4 4 2 tRNA synthetases class I (I, L, M and V) BRF1 PF07741.8 EEQ28536.1 - 0.063 13.5 6.7 0.13 12.5 4.6 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain TPR_8 PF13181.1 EEQ28536.1 - 0.088 12.6 1.3 0.33 10.8 0.9 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Elongin_A PF06881.6 EEQ28536.1 - 0.09 13.1 4.7 0.24 11.8 3.3 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Yae1_N PF09811.4 EEQ28537.1 - 0.00079 18.9 1.3 0.002 17.6 0.9 1.6 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Spt20 PF12090.3 EEQ28538.1 - 3e-48 163.5 0.0 4.6e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Spt20 family LysM PF01476.15 EEQ28540.1 - 1.1e-09 37.9 0.0 1.9e-05 24.4 0.0 3.3 3 0 0 3 3 3 3 LysM domain Synaphin PF05835.7 EEQ28542.1 - 0.032 14.3 0.3 0.057 13.5 0.2 1.3 1 0 0 1 1 1 0 Synaphin protein CD99L2 PF12301.3 EEQ28542.1 - 0.42 10.2 4.1 6.9 6.3 0.0 2.3 1 1 1 2 2 2 0 CD99 antigen like protein 2 Hexapep PF00132.19 EEQ28543.1 - 1.4e-06 27.5 3.0 0.00098 18.5 0.2 3.4 1 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EEQ28543.1 - 0.0062 15.8 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EEQ28543.1 - 0.045 13.8 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain HS1_rep PF02218.10 EEQ28544.1 - 0.013 15.3 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Repeat in HS1/Cortactin CHAP PF05257.11 EEQ28546.1 - 0.12 12.0 0.1 0.76 9.4 0.0 2.0 2 0 0 2 2 2 0 CHAP domain ELO PF01151.13 EEQ28548.1 - 1.4e-58 198.1 5.0 2e-45 155.0 1.1 2.1 2 0 0 2 2 2 2 GNS1/SUR4 family Siah-Interact_N PF09032.6 EEQ28548.1 - 0.097 12.7 0.8 0.17 11.9 0.6 1.3 1 0 0 1 1 1 0 Siah interacting protein, N terminal DUF4222 PF13973.1 EEQ28550.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4222) Fungal_trans_2 PF11951.3 EEQ28551.1 - 0.00036 19.2 2.4 0.00063 18.4 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ28551.1 - 0.0029 17.4 2.1 0.0075 16.1 1.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1500 PF07389.7 EEQ28551.1 - 0.093 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) DUF372 PF04036.7 EEQ28552.1 - 0.63 9.5 2.3 0.87 9.1 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF372) APH PF01636.18 EEQ28553.1 - 1.1e-15 58.0 0.0 3e-15 56.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ28553.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ28553.1 - 0.16 10.5 0.1 0.56 8.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Chitin_bind_3 PF03067.10 EEQ28554.1 - 0.0024 18.1 0.1 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 Chitin binding domain BNR PF02012.15 EEQ28554.1 - 0.21 11.5 0.2 0.21 11.5 0.1 2.9 3 0 0 3 3 3 0 BNR/Asp-box repeat TruD PF01142.13 EEQ28555.1 - 8.3e-50 169.5 0.0 7.1e-47 159.8 0.0 3.3 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) RPE65 PF03055.10 EEQ28557.1 - 6.9e-119 397.5 0.0 7.8e-119 397.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Dynamin_N PF00350.18 EEQ28557.1 - 0.095 12.5 0.0 24 4.7 0.0 2.8 3 0 0 3 3 3 0 Dynamin family SRPRB PF09439.5 EEQ28557.1 - 0.15 11.2 0.0 1.7 7.8 0.0 2.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF2293 PF10056.4 EEQ28558.1 - 6e-29 99.8 0.8 1.1e-28 99.0 0.1 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) DUF3887 PF13026.1 EEQ28558.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) APH PF01636.18 EEQ28559.1 - 2.3e-13 50.4 0.0 3.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ28559.1 - 0.029 13.0 0.0 0.081 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EEQ28559.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mtc PF03820.12 EEQ28561.1 - 3.1e-104 347.9 0.0 6.2e-104 346.9 0.0 1.4 1 1 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.20 EEQ28563.1 - 3.2e-56 190.3 0.0 5.5e-56 189.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28563.1 - 5.3e-20 71.5 0.0 2.3e-19 69.4 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Barwin PF00967.12 EEQ28564.1 - 0.0041 16.7 1.4 0.0054 16.3 0.9 1.4 1 1 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 EEQ28564.1 - 0.01 15.8 1.0 0.031 14.2 0.7 1.8 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel FAD_binding_4 PF01565.18 EEQ28565.1 - 5e-25 87.5 1.4 9.3e-25 86.7 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ28565.1 - 8.1e-15 54.4 0.0 2.4e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like CPSF73-100_C PF11718.3 EEQ28566.1 - 2.7e-68 229.5 0.0 3.6e-66 222.6 0.0 2.3 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EEQ28566.1 - 5.6e-33 113.5 0.0 1.3e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EEQ28566.1 - 6.1e-19 68.4 0.1 1e-18 67.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEQ28566.1 - 1.2e-10 41.3 0.5 2.1e-10 40.4 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EEQ28566.1 - 7.5e-07 28.8 0.2 1.6e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EEQ28566.1 - 0.00012 21.8 0.1 0.00054 19.7 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.9 EEQ28567.1 - 1.3e-13 50.8 4.0 7.3e-08 32.0 2.0 3.1 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Aminotran_3 PF00202.16 EEQ28568.1 - 2.7e-81 273.0 0.0 3.4e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.13 EEQ28569.1 - 6.6e-17 61.2 0.0 1.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ28569.1 - 4.7e-11 42.4 3.6 9.1e-11 41.4 2.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP19 PF01922.12 EEQ28570.1 - 5e-29 100.7 0.0 1.1e-28 99.6 0.0 1.6 2 0 0 2 2 2 1 SRP19 protein PG_binding_1 PF01471.13 EEQ28570.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain TCTP PF00838.12 EEQ28571.1 - 2.2e-58 196.8 2.8 2.5e-58 196.7 1.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Put_Phosphatase PF06888.7 EEQ28571.1 - 0.053 12.6 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative Phosphatase ISG65-75 PF11727.3 EEQ28571.1 - 0.055 12.5 0.7 0.073 12.1 0.5 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein GMC_oxred_N PF00732.14 EEQ28573.1 - 1.8e-46 158.6 0.5 2.8e-46 158.0 0.4 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ28573.1 - 1.6e-28 99.8 0.1 5.3e-28 98.1 0.1 1.9 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EEQ28573.1 - 5.1e-07 28.8 0.2 2.8e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EEQ28573.1 - 6.5e-05 22.0 7.3 0.0013 17.7 5.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ28573.1 - 0.00015 21.7 0.6 0.00058 19.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ28573.1 - 0.00018 20.6 0.1 0.0013 17.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EEQ28573.1 - 0.0038 16.3 0.1 0.0056 15.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EEQ28573.1 - 0.012 15.5 0.5 0.012 15.5 0.4 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EEQ28573.1 - 0.067 12.2 0.5 0.1 11.6 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TIM-br_sig_trns PF09370.5 EEQ28573.1 - 0.071 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 TIM-barrel signal transduction protein Trypan_PARP PF05887.6 EEQ28574.1 - 0.041 13.6 2.8 0.064 13.0 1.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FA_hydroxylase PF04116.8 EEQ28575.1 - 1.3e-10 41.6 7.8 1.3e-10 41.6 5.4 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily UNC-79 PF14776.1 EEQ28575.1 - 0.044 12.1 0.1 0.068 11.5 0.1 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Aldo_ket_red PF00248.16 EEQ28576.1 - 5.4e-59 199.3 0.0 6.1e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MF_alpha_N PF05436.6 EEQ28576.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Kelch_5 PF13854.1 EEQ28577.1 - 1.9e-13 49.9 1.0 6.3e-12 45.1 0.6 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 EEQ28577.1 - 3.3e-06 26.5 1.2 0.02 14.4 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 EEQ28577.1 - 4.8e-06 26.2 0.8 0.00076 19.2 0.1 3.8 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 EEQ28577.1 - 0.00017 21.6 0.3 0.0067 16.5 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EEQ28577.1 - 0.0005 20.1 4.0 0.028 14.6 0.3 4.3 4 1 0 4 4 4 1 Kelch motif BatA PF07584.6 EEQ28577.1 - 0.084 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Pyr_redox_3 PF13738.1 EEQ28582.1 - 4.3e-06 26.9 0.0 8.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Arf PF00025.16 EEQ28583.1 - 7.6e-41 139.2 0.0 1e-26 93.2 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EEQ28583.1 - 2.8e-11 42.7 0.0 4.3e-05 22.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 EEQ28583.1 - 4.3e-08 32.8 0.0 2.1e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 EEQ28583.1 - 1.4e-07 31.0 0.0 0.00098 18.5 0.0 2.4 2 1 0 2 2 2 2 Ras family Miro PF08477.8 EEQ28583.1 - 9.4e-07 29.3 0.0 1.2e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ28583.1 - 1.6e-06 28.0 0.0 2.8e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEQ28583.1 - 1.6e-06 27.4 0.0 2.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEQ28583.1 - 9.2e-06 24.9 0.0 9.1e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EEQ28583.1 - 0.012 15.1 0.0 0.058 12.8 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EEQ28583.1 - 0.029 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4630 PF15443.1 EEQ28583.1 - 0.053 13.3 0.1 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) FeoB_N PF02421.13 EEQ28583.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B PIGA PF08288.7 EEQ28584.1 - 4.8e-46 155.0 1.5 4.8e-46 155.0 1.0 1.8 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EEQ28584.1 - 6.3e-29 100.5 0.0 9.9e-29 99.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEQ28584.1 - 2.9e-16 59.6 0.7 6.1e-16 58.6 0.5 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EEQ28584.1 - 1.1e-13 51.4 0.0 1.8e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEQ28584.1 - 2.5e-13 50.4 0.0 4.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EEQ28584.1 - 2.6e-06 27.3 0.2 4.9e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EEQ28584.1 - 0.00069 19.8 0.0 0.0019 18.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 DEAD PF00270.24 EEQ28585.1 - 5.9e-33 113.7 0.0 1.6e-15 57.0 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ28585.1 - 1.2e-16 60.2 0.3 3.5e-16 58.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ28585.1 - 9.1e-07 28.8 0.0 5.6e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Prp18 PF02840.10 EEQ28586.1 - 1.5e-52 177.3 1.4 1.6e-52 177.1 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EEQ28586.1 - 3.2e-11 42.2 2.5 3.2e-11 42.2 1.7 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CAF-1_p150 PF11600.3 EEQ28586.1 - 0.23 10.8 34.6 0.38 10.1 24.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 EEQ28586.1 - 0.87 7.2 6.2 0.9 7.1 4.3 1.1 1 0 0 1 1 1 0 Ycf1 CDC27 PF09507.5 EEQ28586.1 - 2.8 7.0 27.5 1 8.5 17.3 1.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SAP18 PF06487.7 EEQ28587.1 - 1.5e-44 150.6 0.0 2.1e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) NDUF_B4 PF07225.7 EEQ28588.1 - 0.0001 22.1 0.0 0.00011 22.0 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Nol1_Nop2_Fmu PF01189.12 EEQ28589.1 - 1.7e-15 57.1 0.0 3.2e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_3 PF01596.12 EEQ28589.1 - 0.043 12.8 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Acetyltransf_1 PF00583.19 EEQ28590.1 - 1.5e-10 40.9 2.0 4.6e-10 39.3 1.4 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ28590.1 - 2.7e-08 33.8 0.0 4.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EEQ28590.1 - 4.3e-08 33.6 0.0 7.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ28590.1 - 7.5e-05 22.8 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ28590.1 - 0.00013 21.6 0.0 0.00029 20.5 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EEQ28590.1 - 0.00023 21.0 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EEQ28590.1 - 0.0022 18.1 0.0 0.0039 17.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ28590.1 - 0.022 14.6 0.1 0.052 13.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FYVE PF01363.16 EEQ28591.1 - 1.6e-14 53.5 5.5 2.3e-14 53.0 3.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EEQ28591.1 - 0.047 13.5 1.9 0.11 12.4 1.3 1.5 1 0 0 1 1 1 0 IBR domain zf-AN1 PF01428.11 EEQ28591.1 - 0.052 13.4 9.3 0.1 12.5 6.4 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger BTB_2 PF02214.17 EEQ28592.1 - 3e-08 33.7 0.0 5.2e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 EEQ28592.1 - 0.017 15.0 0.0 0.077 12.9 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Peptidase_S8 PF00082.17 EEQ28594.1 - 3.4e-48 164.2 11.8 5.3e-48 163.5 8.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ28594.1 - 1.5e-15 57.4 0.0 3.7e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 ketoacyl-synt PF00109.21 EEQ28595.1 - 4.2e-07 29.7 0.0 2.8e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Peptidase_M4_C PF02868.10 EEQ28595.1 - 0.022 14.5 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Vps26 PF03643.10 EEQ28595.1 - 0.032 13.0 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Pkinase PF00069.20 EEQ28596.1 - 1.4e-08 34.2 0.0 2.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28596.1 - 0.00013 21.1 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_26 PF13443.1 EEQ28598.1 - 0.053 13.7 0.2 0.078 13.1 0.2 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Methyltransf_23 PF13489.1 EEQ28599.1 - 1.5e-05 24.7 0.0 1.9e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ28599.1 - 2.4e-05 24.6 0.2 9.9e-05 22.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ28599.1 - 0.015 14.9 0.1 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ28599.1 - 0.016 14.6 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_11 PF08241.7 EEQ28599.1 - 0.019 15.4 0.0 0.029 14.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EEQ28601.1 - 4.6e-20 71.6 45.9 6.3e-11 41.5 13.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ28601.1 - 0.032 14.0 4.7 0.058 13.1 1.9 2.4 2 0 0 2 2 2 0 MFS_1 like family VCBS PF13517.1 EEQ28605.1 - 1.4e-28 98.9 40.5 5.1e-09 36.3 3.5 4.7 1 1 4 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EEQ28605.1 - 1.4e-18 65.9 18.1 0.0017 17.9 0.0 6.2 6 0 0 6 6 6 5 FG-GAP repeat Lipase_GDSL_2 PF13472.1 EEQ28605.1 - 2.9e-16 60.1 0.1 5.2e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ28605.1 - 1.7e-13 50.9 0.3 2.8e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 EEQ28605.1 - 1.2e-08 34.5 4.8 0.49 9.8 0.0 5.3 4 1 1 5 5 5 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 EEQ28605.1 - 1.9e-05 24.5 0.0 3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SUR7 PF06687.7 EEQ28609.1 - 2.9e-36 125.0 8.6 3.4e-36 124.8 6.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Acetyltransf_1 PF00583.19 EEQ28611.1 - 2.6e-14 53.0 0.0 3.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEQ28611.1 - 2.1e-07 30.5 0.0 3.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ28611.1 - 0.00035 20.6 0.0 0.00051 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ28611.1 - 0.0038 17.0 0.1 0.0061 16.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ28611.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Macoilin PF09726.4 EEQ28612.1 - 1.4e-06 26.9 20.5 1.9e-06 26.4 14.2 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF4646 PF15496.1 EEQ28612.1 - 0.035 14.1 2.2 0.26 11.3 1.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) Pkinase PF00069.20 EEQ28613.1 - 0.0092 15.1 0.0 0.061 12.4 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain HEAT_EZ PF13513.1 EEQ28613.1 - 0.047 14.1 0.8 0.19 12.2 0.1 2.4 2 0 0 2 2 2 0 HEAT-like repeat LsmAD PF06741.8 EEQ28614.1 - 9.5e-28 96.1 5.1 2.4e-27 94.8 3.6 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 EEQ28614.1 - 7.4e-13 48.2 0.0 1.9e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.8 EEQ28615.1 - 3.1e-151 504.0 4.4 4.2e-151 503.6 3.1 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 EEQ28615.1 - 0.0016 17.8 0.1 0.0057 16.0 0.1 2.0 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain DUF1664 PF07889.7 EEQ28615.1 - 0.22 11.3 3.6 0.4 10.4 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3138 PF11336.3 EEQ28615.1 - 0.29 9.2 2.2 0.47 8.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) COG2 PF06148.6 EEQ28615.1 - 0.43 10.4 4.9 10 6.0 0.0 3.8 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 EEQ28615.1 - 0.95 9.7 4.6 0.7 10.1 0.1 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Granulin PF00396.13 EEQ28616.1 - 0.0058 16.7 4.7 0.0058 16.7 3.3 6.4 3 3 2 5 5 5 2 Granulin DUF3761 PF12587.3 EEQ28616.1 - 1.9 8.6 9.2 0.2 11.8 2.7 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3761) ACOX PF01756.14 EEQ28617.1 - 1.6e-35 122.1 0.0 3e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EEQ28617.1 - 6.4e-31 107.2 0.7 1.3e-30 106.2 0.5 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EEQ28617.1 - 1.1e-12 47.2 0.2 3.5e-12 45.6 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EEQ28617.1 - 2.7e-07 30.8 0.1 0.002 18.2 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain ESSS PF10183.4 EEQ28618.1 - 3.1e-27 95.0 0.0 3.6e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RNB PF00773.14 EEQ28619.1 - 6.2e-94 314.9 0.1 1.4e-93 313.7 0.0 1.6 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EEQ28619.1 - 3e-08 33.8 1.1 8.1e-08 32.4 0.3 2.1 2 0 0 2 2 2 1 PIN domain MFS_1 PF07690.11 EEQ28620.1 - 1.3e-26 93.2 73.0 1.3e-21 76.7 29.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily LIM PF00412.17 EEQ28621.1 - 6.2e-27 93.4 23.6 1.1e-10 41.3 0.8 4.0 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.1 EEQ28621.1 - 0.036 14.3 3.0 0.05 13.8 0.0 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Methyltransf_4 PF02390.12 EEQ28622.1 - 6.1e-49 165.7 0.0 1.4e-47 161.2 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EEQ28622.1 - 4.4e-06 27.2 0.0 7.3e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ28622.1 - 0.00043 20.3 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ28622.1 - 0.00088 19.6 0.0 0.0034 17.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EEQ28622.1 - 0.0017 17.7 0.0 0.023 14.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EEQ28622.1 - 0.002 17.6 0.0 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ28622.1 - 0.0021 18.5 0.0 0.31 11.5 0.0 3.5 4 0 0 4 4 4 1 Methyltransferase domain FmrO PF07091.6 EEQ28622.1 - 0.0041 16.1 0.0 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_12 PF08242.7 EEQ28622.1 - 0.0047 17.3 0.0 0.015 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain ESCRT-II PF05871.7 EEQ28623.1 - 1.2e-51 174.2 1.6 1.5e-51 173.9 1.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit BRCT PF00533.21 EEQ28624.1 - 2.7e-33 113.9 0.2 2.5e-08 33.9 0.0 6.6 6 1 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEQ28624.1 - 4e-27 93.8 2.7 9.9e-18 63.7 0.2 5.7 6 1 0 6 6 6 3 twin BRCT domain Abhydrolase_6 PF12697.2 EEQ28625.1 - 5.5e-12 46.0 0.0 3.6e-11 43.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ceramidase PF05875.7 EEQ28626.1 - 2.5e-90 302.1 6.8 3.6e-90 301.6 4.7 1.2 1 0 0 1 1 1 1 Ceramidase Prefoldin_2 PF01920.15 EEQ28628.1 - 4.4e-07 29.6 0.3 7e-07 28.9 0.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF4140 PF13600.1 EEQ28628.1 - 0.024 15.1 1.0 0.03 14.7 0.7 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GatB_Yqey PF02637.13 EEQ28628.1 - 0.043 13.5 0.4 0.052 13.2 0.3 1.1 1 0 0 1 1 1 0 GatB domain Mito_carr PF00153.22 EEQ28630.1 - 6.6e-56 186.0 2.4 1.1e-19 69.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Synaphin PF05835.7 EEQ28632.1 - 5.6 7.1 10.2 9.4 6.3 7.1 1.4 1 1 0 1 1 1 0 Synaphin protein Pkinase PF00069.20 EEQ28633.1 - 1.4e-32 112.8 0.0 3.1e-32 111.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28633.1 - 1.3e-14 53.9 0.0 8.1e-14 51.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ28633.1 - 0.0094 15.7 0.6 0.085 12.5 0.2 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Myc_target_1 PF15179.1 EEQ28634.1 - 0.38 10.3 5.3 0.24 10.9 0.2 2.3 1 1 1 2 2 2 0 Myc target protein 1 Rcd1 PF04078.8 EEQ28635.1 - 8.3e-131 434.5 2.9 1.1e-130 434.2 2.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Ycf1 PF05758.7 EEQ28635.1 - 0.0037 15.0 0.4 0.0063 14.3 0.6 1.3 2 0 0 2 2 2 1 Ycf1 Macoilin PF09726.4 EEQ28635.1 - 0.28 9.4 11.5 0.35 9.1 8.0 1.1 1 0 0 1 1 1 0 Transmembrane protein PAT1 PF09770.4 EEQ28635.1 - 1 7.4 39.0 1.3 7.2 27.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EEQ28635.1 - 1.4 7.0 50.7 1.6 6.8 35.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DNA_pol_viral_N PF00242.12 EEQ28635.1 - 2.3 7.1 17.3 3.1 6.7 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PHD PF00628.24 EEQ28636.1 - 8.3e-09 35.0 9.1 1.9e-08 33.8 6.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEQ28636.1 - 0.0014 17.9 4.6 0.0014 17.9 3.2 2.2 2 0 0 2 2 2 1 PHD-finger GARS_C PF02843.11 EEQ28637.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain AXE1 PF05448.7 EEQ28638.1 - 0.11 11.0 0.0 0.12 10.8 0.0 1.0 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HMG_box PF00505.14 EEQ28640.1 - 5e-10 39.5 0.9 5e-10 39.5 0.6 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box Sld5 PF05916.6 EEQ28641.1 - 8.3e-12 45.3 2.6 1e-11 45.0 1.0 1.7 1 1 1 2 2 2 1 GINS complex protein INT_SG_DDX_CT_C PF15300.1 EEQ28641.1 - 0.066 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus DUF3016 PF11454.3 EEQ28641.1 - 0.071 12.6 0.1 0.32 10.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3016) Sulfate_transp PF00916.15 EEQ28642.1 - 1.1e-39 136.0 7.7 1.1e-39 136.0 5.3 1.9 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EEQ28642.1 - 3.4e-14 52.4 0.0 6.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EEQ28642.1 - 2.9e-13 49.2 0.1 5.4e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain PH_6 PF15406.1 EEQ28643.1 - 1.6e-34 118.2 1.4 1.6e-34 118.2 1.0 3.5 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EEQ28643.1 - 2.7e-06 27.5 0.0 9.8e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 PH domain PNTB PF02233.11 EEQ28645.1 - 1.2e-171 571.6 25.0 1.2e-171 571.6 17.3 1.6 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EEQ28645.1 - 6.9e-50 168.8 0.1 1.5e-49 167.7 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EEQ28645.1 - 6.7e-44 149.1 0.0 1.7e-43 147.8 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EEQ28645.1 - 2.1e-23 82.2 5.3 1.4e-12 47.6 0.2 6.0 4 3 2 7 7 7 2 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EEQ28645.1 - 0.0048 16.0 0.1 0.82 8.7 0.0 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EEQ28645.1 - 0.026 14.0 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_2 PF07992.9 EEQ28645.1 - 0.055 13.3 0.9 0.13 12.1 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.17 EEQ28645.1 - 0.075 12.7 0.6 0.7 9.6 0.2 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain GIDA PF01134.17 EEQ28645.1 - 0.083 11.7 0.8 0.15 10.9 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_18 PF12847.2 EEQ28645.1 - 0.085 13.4 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 EEQ28645.1 - 0.085 12.8 1.6 0.77 9.8 1.1 2.8 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EEQ28645.1 - 2.3 8.3 6.4 41 4.2 0.0 4.2 5 1 0 5 5 4 0 Shikimate / quinate 5-dehydrogenase DUF3938 PF13074.1 EEQ28645.1 - 4.5 7.1 6.6 7.9 6.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) bZIP_1 PF00170.16 EEQ28646.1 - 3.9e-12 45.9 3.7 6.2e-12 45.2 2.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ28646.1 - 5.4e-09 35.7 6.8 1.1e-08 34.7 4.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEQ28646.1 - 0.073 13.3 5.9 0.14 12.4 4.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Sugarporin_N PF11471.3 EEQ28646.1 - 0.21 11.2 4.3 0.37 10.4 3.0 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Asn_synthase PF00733.16 EEQ28647.1 - 4.1e-54 183.7 0.0 5.5e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EEQ28647.1 - 2.9e-05 23.8 0.0 0.00027 20.6 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain VPS9 PF02204.13 EEQ28648.1 - 3.4e-29 100.9 0.0 6.2e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain VIT1 PF01988.14 EEQ28650.1 - 5.5e-59 199.2 3.8 6.4e-59 199.0 2.7 1.0 1 0 0 1 1 1 1 VIT family Abi PF02517.11 EEQ28650.1 - 0.14 12.2 1.8 0.22 11.6 1.2 1.5 1 1 0 1 1 1 0 CAAX protease self-immunity DUF4282 PF14110.1 EEQ28650.1 - 9.3 6.5 9.7 23 5.2 4.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF4202 PF13875.1 EEQ28651.1 - 2.8e-81 271.6 1.4 3.1e-81 271.4 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) AAA PF00004.24 EEQ28651.1 - 0.0026 17.9 0.1 0.16 12.1 0.0 2.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Thr_synth_N PF14821.1 EEQ28652.1 - 1.5e-28 98.6 0.0 3.5e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EEQ28652.1 - 6.8e-20 71.5 0.0 2.3e-19 69.7 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HAD_2 PF13419.1 EEQ28653.1 - 1e-32 113.7 0.0 1.4e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF387 PF04079.11 EEQ28653.1 - 0.017 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) HALZ PF02183.13 EEQ28653.1 - 0.14 11.9 0.2 0.29 10.8 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Hydrolase PF00702.21 EEQ28653.1 - 0.16 12.3 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rox3 PF08633.5 EEQ28654.1 - 4.7e-51 173.8 0.4 7.8e-51 173.1 0.0 1.5 2 0 0 2 2 2 1 Rox3 mediator complex subunit Fungal_trans PF04082.13 EEQ28655.1 - 2.2e-16 59.5 0.5 5.1e-15 55.0 0.4 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ28655.1 - 7.3e-08 32.2 13.4 1.5e-07 31.2 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.10 EEQ28655.1 - 0.073 12.5 0.2 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Peptidase_M14 PF00246.19 EEQ28656.1 - 2.9e-78 263.3 0.1 1e-77 261.5 0.0 1.7 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EEQ28656.1 - 9.4e-12 44.4 0.0 2.3e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide AstE_AspA PF04952.9 EEQ28656.1 - 0.022 13.6 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_S8 PF00082.17 EEQ28657.1 - 4.3e-41 140.9 9.5 6.4e-41 140.3 6.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ28657.1 - 2e-14 53.8 0.0 4.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Endothelin PF00322.12 EEQ28659.1 - 8.9 5.6 6.8 0.43 9.8 0.3 2.1 3 0 0 3 3 3 0 Endothelin family p450 PF00067.17 EEQ28660.1 - 2.3e-62 211.0 0.0 3.5e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PYNP_C PF07831.8 EEQ28660.1 - 0.18 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Arylsulfotran_2 PF14269.1 EEQ28661.1 - 1.9e-109 365.4 1.0 2.6e-109 364.9 0.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) FA_hydroxylase PF04116.8 EEQ28662.1 - 3.2e-11 43.6 15.1 3.2e-11 43.6 10.5 2.7 2 2 1 3 3 3 1 Fatty acid hydroxylase superfamily p450 PF00067.17 EEQ28663.1 - 9.3e-16 57.3 0.0 1.3e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EEQ28664.1 - 6.9e-17 61.1 0.1 1e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ28664.1 - 4.2e-08 32.9 9.2 9.2e-08 31.8 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IU_nuc_hydro PF01156.14 EEQ28666.1 - 1.5e-29 103.2 0.0 2.5e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.15 EEQ28666.1 - 0.11 12.4 0.1 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain HLH PF00010.21 EEQ28667.1 - 5.4e-15 54.8 0.7 1.2e-14 53.7 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain LELP1 PF15042.1 EEQ28667.1 - 0.016 15.3 2.9 0.034 14.3 2.0 1.7 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Glycos_transf_1 PF00534.15 EEQ28669.1 - 9.1e-14 51.2 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEQ28669.1 - 0.00088 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EEQ28669.1 - 0.037 14.3 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Amidase PF01425.16 EEQ28671.1 - 6.9e-91 305.3 0.0 8e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 Amidase SURF4 PF02077.10 EEQ28674.1 - 5.8e-95 317.6 6.1 6.6e-95 317.5 4.2 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 EEQ28674.1 - 0.096 12.2 0.2 0.22 11.0 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) DoxX PF07681.7 EEQ28674.1 - 0.19 12.1 20.9 0.11 12.8 3.3 3.0 3 2 0 3 3 3 0 DoxX LSM PF01423.17 EEQ28677.1 - 5.5e-17 61.0 0.1 7.5e-17 60.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain WH2 PF02205.15 EEQ28678.1 - 1.3e-10 40.5 0.5 1.3e-10 40.5 0.3 1.9 2 0 0 2 2 2 1 WH2 motif Ribosomal_L1 PF00687.16 EEQ28680.1 - 1.2e-52 178.4 0.3 1.5e-52 178.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Acetyltransf_1 PF00583.19 EEQ28681.1 - 2.7e-10 40.1 0.0 8e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEQ28681.1 - 6e-07 29.1 0.0 4.6e-06 26.3 0.0 2.2 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ28681.1 - 9.8e-06 25.6 0.0 0.0002 21.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ28681.1 - 3.2e-05 24.0 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEQ28681.1 - 0.0001 22.5 0.0 0.0002 21.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ28681.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Arf PF00025.16 EEQ28682.1 - 2.5e-79 264.5 0.2 2.8e-79 264.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ28682.1 - 1.7e-15 56.6 0.0 2.1e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEQ28682.1 - 2.1e-13 49.9 0.0 2.3e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEQ28682.1 - 2.2e-12 46.3 1.9 2.1e-09 36.5 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEQ28682.1 - 3.4e-11 42.7 0.0 4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEQ28682.1 - 3e-08 34.1 0.0 4.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ28682.1 - 3.6e-06 26.9 0.0 4.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ28682.1 - 0.006 16.0 0.1 0.049 13.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EEQ28682.1 - 0.0078 15.3 0.4 0.023 13.8 0.1 1.6 1 1 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EEQ28682.1 - 0.042 13.7 0.3 0.13 12.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain APH PF01636.18 EEQ28685.1 - 1.3e-15 57.7 0.0 3.4e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ28685.1 - 0.00071 18.3 0.0 0.038 12.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) PP28 PF10252.4 EEQ28685.1 - 0.24 11.4 2.0 0.29 11.1 0.2 1.9 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 DUF92 PF01940.11 EEQ28687.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 DUF3357 PF11837.3 EEQ28687.1 - 0.016 15.0 0.0 0.05 13.4 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Plasmodium_Vir PF05795.6 EEQ28687.1 - 0.045 12.9 0.1 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3405 PF11885.3 EEQ28688.1 - 3.5e-220 731.4 0.9 4.1e-220 731.1 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Sod_Cu PF00080.15 EEQ28690.1 - 9.1e-17 61.5 0.2 1.5e-16 60.8 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 EEQ28690.1 - 0.00085 19.9 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 CHRD domain Collagen PF01391.13 EEQ28691.1 - 0.0013 18.2 3.4 0.0013 18.2 2.4 1.7 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) CDC45 PF02724.9 EEQ28691.1 - 0.25 9.3 10.7 0.33 8.9 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 EEQ28691.1 - 2.4 6.7 13.5 3.3 6.3 9.4 1.3 1 0 0 1 1 1 0 Paf1 Prog_receptor PF02161.10 EEQ28691.1 - 2.7 6.6 6.4 3.6 6.3 4.4 1.2 1 0 0 1 1 1 0 Progesterone receptor Daxx PF03344.10 EEQ28691.1 - 4.2 5.7 16.9 5.3 5.4 11.7 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EEQ28691.1 - 4.7 5.0 18.7 5.9 4.6 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family Choline_kinase PF01633.15 EEQ28692.1 - 4.7e-48 163.5 0.0 5.5e-47 160.0 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EEQ28692.1 - 2.8e-10 40.3 0.4 8.9e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ28692.1 - 0.016 14.3 0.0 0.074 12.1 0.0 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase CHORD PF04968.7 EEQ28693.1 - 8.4e-53 176.4 16.2 5.9e-27 93.7 2.6 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EEQ28693.1 - 2.8e-13 50.1 0.1 4.3e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.9 EEQ28694.1 - 3.9e-14 52.6 0.0 4.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EEQ28694.1 - 0.0041 17.0 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin HpcH_HpaI PF03328.9 EEQ28695.1 - 6.4e-33 113.5 0.0 7.9e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PagL PF09411.5 EEQ28695.1 - 0.071 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipid A 3-O-deacylase (PagL) HNH_2 PF13391.1 EEQ28696.1 - 1.4e-12 47.1 0.0 2.9e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Fungal_trans PF04082.13 EEQ28697.1 - 1.1e-19 70.3 0.0 1.6e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ28697.1 - 1.1e-12 47.6 27.7 7.4e-07 28.9 5.4 2.4 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 EEQ28698.1 - 2.1e-30 105.8 0.2 3e-30 105.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ28698.1 - 6.4e-21 73.6 1.0 1.1e-20 72.8 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEQ28698.1 - 5.2e-11 43.1 0.3 2.2e-10 41.1 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEQ28698.1 - 0.00012 22.2 0.1 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 14-3-3 PF00244.15 EEQ28699.1 - 1.5e-10 40.5 0.1 2.7e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein tRNA-synt_1b PF00579.20 EEQ28700.1 - 1.9e-17 63.3 0.0 1.8e-16 60.1 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Metallophos PF00149.23 EEQ28702.1 - 1.5e-08 34.2 2.3 3.4e-08 33.1 1.6 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_S64 PF08192.6 EEQ28703.1 - 0.19 9.9 0.0 0.31 9.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF3237 PF11578.3 EEQ28704.1 - 5.5e-31 106.8 0.1 1.3e-29 102.4 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) GRP PF07172.6 EEQ28705.1 - 0.00041 20.7 7.8 0.0006 20.2 5.4 1.3 1 0 0 1 1 1 1 Glycine rich protein family DUF2681 PF10883.3 EEQ28705.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Trp_oprn_chp PF09534.5 EEQ28705.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EMP24_GP25L PF01105.19 EEQ28706.1 - 6.6e-47 159.5 0.0 8e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Myb_DNA-bind_6 PF13921.1 EEQ28707.1 - 0.0054 16.8 5.3 0.025 14.6 0.7 2.9 3 1 0 3 3 3 1 Myb-like DNA-binding domain HEPPP_synt_1 PF07307.6 EEQ28707.1 - 0.12 11.8 0.2 0.12 11.8 0.1 1.6 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Myb_DNA-bind_3 PF12776.2 EEQ28707.1 - 0.14 12.7 6.5 0.6 10.7 0.0 3.2 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Glyco_hydro_17 PF00332.13 EEQ28708.1 - 2.1e-21 76.2 0.0 7.2e-20 71.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PAM2 PF07145.10 EEQ28709.1 - 0.0048 16.3 9.4 0.57 9.8 0.0 4.3 3 0 0 3 3 3 3 Ataxin-2 C-terminal region DUF3425 PF11905.3 EEQ28710.1 - 1.4e-15 57.4 0.7 3.6e-15 56.0 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EEQ28710.1 - 0.0022 17.9 18.6 0.036 14.0 12.9 2.2 1 1 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.6 EEQ28710.1 - 0.021 14.5 2.3 0.039 13.6 1.6 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF1556 PF07590.6 EEQ28710.1 - 0.12 12.6 3.3 0.089 13.0 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1556) DUF2937 PF11157.3 EEQ28710.1 - 0.41 9.9 1.8 0.65 9.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) GBP_C PF02841.9 EEQ28710.1 - 2.3 7.3 11.5 3.2 6.8 7.9 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain bZIP_2 PF07716.10 EEQ28710.1 - 6.6 6.6 23.6 3.9e+02 0.9 16.3 2.2 1 1 0 1 1 1 0 Basic region leucine zipper GLE1 PF07817.8 EEQ28711.1 - 3.5e-13 49.0 3.3 4.1e-13 48.8 0.0 2.5 1 1 1 2 2 2 1 GLE1-like protein MIP-T3 PF10243.4 EEQ28711.1 - 0.068 11.6 46.0 0.096 11.1 31.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RNB PF00773.14 EEQ28712.1 - 1.4e-81 274.3 0.0 1.4e-81 274.3 0.0 2.0 3 0 0 3 3 3 1 RNB domain UQ_con PF00179.21 EEQ28713.1 - 5.7e-35 119.7 0.3 1.2e-34 118.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ28713.1 - 0.00018 21.2 0.0 0.00051 19.8 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic E2 family B Hid1 PF12722.2 EEQ28713.1 - 0.44 8.1 3.1 0.66 7.5 2.2 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleoplasmin PF03066.10 EEQ28713.1 - 6.4 6.2 8.9 1 8.9 2.3 2.4 3 0 0 3 3 3 0 Nucleoplasmin SOG2 PF10428.4 EEQ28714.1 - 3.9 6.0 5.3 4.2 5.9 3.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SSP160 PF06933.6 EEQ28714.1 - 6.4 4.6 15.3 6.8 4.5 10.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MMgT PF10270.4 EEQ28715.1 - 2.3e-28 98.7 0.0 2.7e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.14 EEQ28716.1 - 4.3e-31 106.4 2.5 7.4e-31 105.7 1.7 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EEQ28716.1 - 2.6e-08 33.8 0.1 2.6e-08 33.8 0.1 2.7 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region AAA_2 PF07724.9 EEQ28717.1 - 5e-46 156.7 0.0 4.3e-44 150.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EEQ28717.1 - 1.1e-25 89.3 0.1 1.1e-25 89.3 0.1 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EEQ28717.1 - 1.8e-18 67.0 0.0 2e-09 37.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ28717.1 - 1.2e-12 47.7 0.0 1.6e-07 31.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEQ28717.1 - 1.4e-09 38.1 13.5 0.00025 21.1 0.0 5.6 4 2 1 6 6 6 3 AAA ATPase domain AAA_22 PF13401.1 EEQ28717.1 - 2.4e-09 37.3 0.5 0.00097 19.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EEQ28717.1 - 5.6e-08 32.4 0.2 0.00022 20.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EEQ28717.1 - 3.7e-06 26.8 0.1 0.083 12.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EEQ28717.1 - 1.5e-05 24.7 0.4 0.1 12.2 0.0 2.8 3 0 0 3 3 2 2 NACHT domain IstB_IS21 PF01695.12 EEQ28717.1 - 2.1e-05 24.0 0.0 0.071 12.5 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 EEQ28717.1 - 4.6e-05 23.7 2.9 0.044 14.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EEQ28717.1 - 0.00016 22.4 4.9 0.53 11.1 0.0 3.9 4 1 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EEQ28717.1 - 0.00017 21.2 0.0 0.015 15.0 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 EEQ28717.1 - 0.00023 20.9 8.3 0.11 12.2 0.1 4.6 3 2 0 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 EEQ28717.1 - 0.00024 21.1 1.2 0.056 13.4 0.0 3.5 3 1 0 4 4 3 1 AAA domain AAA_25 PF13481.1 EEQ28717.1 - 0.0004 19.8 0.4 0.16 11.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EEQ28717.1 - 0.00043 19.9 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 EEQ28717.1 - 0.00084 18.0 0.1 0.14 10.7 0.0 2.6 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 EEQ28717.1 - 0.0011 18.4 0.0 0.14 11.6 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EEQ28717.1 - 0.0025 18.0 1.2 0.34 11.2 0.0 3.0 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 EEQ28717.1 - 0.0027 16.8 0.2 1.6 7.8 0.1 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEQ28717.1 - 0.0038 17.3 0.1 1.6 8.9 0.0 2.9 2 1 0 2 2 2 1 RNA helicase ResIII PF04851.10 EEQ28717.1 - 0.0044 16.8 2.6 3 7.6 0.1 3.5 3 2 1 4 4 4 1 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 EEQ28717.1 - 0.0099 15.3 0.0 0.67 9.4 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EEQ28717.1 - 0.017 15.6 0.1 1.4 9.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 EEQ28717.1 - 0.02 14.4 2.1 0.29 10.6 0.0 3.6 5 0 0 5 5 4 0 AAA domain DUF258 PF03193.11 EEQ28717.1 - 0.021 14.0 0.1 5 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EEQ28717.1 - 0.023 14.5 0.1 7.1 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EEQ28717.1 - 0.027 13.5 0.0 0.72 8.9 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin ERM PF00769.14 EEQ28717.1 - 0.033 13.7 12.0 0.059 12.9 8.3 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF815 PF05673.8 EEQ28717.1 - 0.035 13.0 0.3 0.49 9.2 0.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EEQ28717.1 - 0.047 13.2 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EEQ28717.1 - 0.067 12.8 0.1 16 5.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 EEQ28717.1 - 0.07 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.12 EEQ28717.1 - 0.075 12.5 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EEQ28717.1 - 0.11 12.0 0.1 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain UvrD-helicase PF00580.16 EEQ28717.1 - 0.14 11.3 3.8 0.6 9.3 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain V_ATPase_I PF01496.14 EEQ28717.1 - 4.3 5.0 4.9 6.1 4.5 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MutS_III PF05192.13 EEQ28718.1 - 3.5e-24 85.7 0.0 5.4e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.16 EEQ28718.1 - 5e-20 71.9 0.0 1.3e-15 57.4 0.0 2.3 2 0 0 2 2 2 2 MutS domain V MutS_IV PF05190.13 EEQ28718.1 - 0.0039 17.3 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 MutS family domain IV DUF3885 PF13021.1 EEQ28718.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) Sas10 PF09368.5 EEQ28719.1 - 1.5e-29 101.9 7.1 1.5e-29 101.9 4.9 2.8 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EEQ28719.1 - 1.5e-13 50.6 0.0 7.7e-13 48.4 0.0 2.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family adh_short PF00106.20 EEQ28720.1 - 1.3e-23 83.7 0.0 1.8e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ28720.1 - 7.3e-12 45.3 0.0 2e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ28720.1 - 6.7e-06 26.0 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEQ28720.1 - 8.1e-05 22.7 0.6 0.00064 19.7 0.1 2.5 2 2 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EEQ28720.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EEQ28720.1 - 0.0014 18.6 0.2 0.005 16.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EEQ28720.1 - 0.0016 18.1 1.6 0.0023 17.6 0.3 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_transf_4 PF13439.1 EEQ28720.1 - 0.0032 17.2 0.0 0.0078 15.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 NAD_binding_7 PF13241.1 EEQ28720.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 EEQ28720.1 - 0.011 14.7 0.1 0.022 13.8 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EEQ28720.1 - 0.031 13.9 0.1 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EEQ28720.1 - 0.072 11.9 0.0 0.41 9.5 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FA_hydroxylase PF04116.8 EEQ28721.1 - 1.9e-12 47.5 9.8 1.9e-12 47.5 6.8 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.14 EEQ28722.1 - 5.4e-35 119.9 0.1 8e-35 119.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.8 EEQ28723.1 - 1.7e-28 98.5 0.0 2.5e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ion_trans PF00520.26 EEQ28724.1 - 5.9e-106 352.1 82.0 4.2e-33 114.2 4.2 5.1 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.27 EEQ28724.1 - 0.01 15.1 0.0 0.026 13.8 0.0 1.8 1 0 0 1 1 1 1 EF hand SET PF00856.23 EEQ28726.1 - 1.2e-19 71.2 0.2 5.4e-19 69.0 0.2 2.2 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EEQ28726.1 - 9.6e-11 41.8 3.5 9.6e-11 41.8 2.4 2.2 2 0 0 2 2 2 1 Pre-SET motif HNH_2 PF13391.1 EEQ28727.1 - 0.015 15.0 0.0 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 HNH endonuclease Nop52 PF05997.7 EEQ28728.1 - 2.9e-49 167.4 0.2 5.2e-40 137.1 0.3 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TAN PF11640.3 EEQ28728.1 - 0.027 14.1 0.1 0.053 13.2 0.1 1.5 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Secretin_N_2 PF07655.8 EEQ28728.1 - 0.055 13.8 1.1 0.055 13.8 0.8 1.6 2 0 0 2 2 2 0 Secretin N-terminal domain NOT2_3_5 PF04153.13 EEQ28728.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family ubiquitin PF00240.18 EEQ28729.1 - 0.0046 16.3 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEQ28729.1 - 0.0053 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PaREP1 PF05942.6 EEQ28729.1 - 0.06 13.2 0.2 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family DUF1604 PF07713.8 EEQ28730.1 - 4.7e-41 138.4 3.1 2.3e-39 133.0 1.8 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EEQ28730.1 - 1.1e-07 31.4 1.2 3.6e-07 29.8 0.5 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EEQ28730.1 - 0.04 13.7 0.1 0.04 13.7 0.1 3.3 3 0 0 3 3 3 0 DExH-box splicing factor binding site SLT_2 PF13406.1 EEQ28730.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain Pkinase PF00069.20 EEQ28731.1 - 5.6e-77 258.4 0.0 1.1e-76 257.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28731.1 - 5.2e-41 140.4 0.0 1.5e-40 138.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EEQ28731.1 - 9.4e-17 60.1 0.2 1.6e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EEQ28731.1 - 1.7e-06 27.2 0.0 3.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ28731.1 - 2.1e-05 23.6 0.0 0.00011 21.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ28731.1 - 0.0017 18.1 0.1 0.033 13.9 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EEQ28731.1 - 0.0054 15.9 0.1 0.009 15.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 EEQ28731.1 - 0.0087 15.4 0.5 0.023 14.0 0.4 1.7 1 1 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EEQ28731.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DAGK_cat PF00781.19 EEQ28732.1 - 8.2e-25 86.7 0.1 1.4e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.15 EEQ28735.1 - 2.1e-93 313.4 11.7 2.1e-93 313.4 8.1 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EEQ28735.1 - 1.6e-61 205.7 0.0 7.4e-61 203.6 0.0 2.2 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EEQ28735.1 - 2.3e-61 205.5 0.6 5.1e-61 204.4 0.4 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EEQ28735.1 - 3.3e-12 46.5 7.6 2.2e-07 31.0 0.0 4.4 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 EEQ28735.1 - 2.1e-06 28.0 3.1 0.00049 20.5 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 EEQ28735.1 - 1.9e-05 24.5 10.8 0.028 14.2 0.1 4.1 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EEQ28735.1 - 0.00032 20.5 0.3 0.96 9.7 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat RE_Alw26IDE PF09665.5 EEQ28735.1 - 0.026 13.2 2.3 1.5 7.4 0.2 2.9 2 1 0 2 2 2 0 Type II restriction endonuclease (RE_Alw26IDE) AP4E_app_platf PF14807.1 EEQ28735.1 - 0.056 13.6 0.1 0.26 11.5 0.1 2.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Arm PF00514.18 EEQ28735.1 - 0.35 10.7 2.0 8.8 6.3 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Mago_nashi PF02792.9 EEQ28736.1 - 6.9e-52 174.9 7.6 1.6e-45 154.3 0.2 2.0 1 1 1 2 2 2 2 Mago nashi protein Vac_ImportDeg PF09783.4 EEQ28737.1 - 5.5e-64 214.9 1.7 7e-64 214.5 1.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Methyltransf_12 PF08242.7 EEQ28738.1 - 2.5e-06 27.8 0.0 5.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ28738.1 - 2.6e-05 24.7 0.0 0.00013 22.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ28738.1 - 5.8e-05 22.8 0.0 8.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ28738.1 - 0.069 13.5 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ28738.1 - 0.072 13.1 0.3 1 9.4 0.0 2.7 2 2 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ28738.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pro-kuma_activ PF09286.6 EEQ28740.1 - 7.7e-39 132.9 0.8 1.8e-38 131.8 0.2 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEQ28740.1 - 4.5e-07 29.3 0.3 1.1e-06 27.9 0.2 1.6 1 1 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 EEQ28742.1 - 5e-74 244.7 0.1 4.8e-19 68.4 0.0 7.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ28742.1 - 2.7e-47 156.2 0.4 0.0003 20.4 0.0 12.5 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.1 EEQ28742.1 - 2.3e-46 155.3 0.2 1.1e-07 32.1 0.0 10.0 8 3 5 13 13 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ28742.1 - 2e-40 135.8 3.3 2e-07 31.0 0.0 9.9 4 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ28742.1 - 2.1e-38 126.4 0.0 0.0089 16.1 0.0 13.3 13 0 0 13 13 13 8 Ankyrin repeat Aa_trans PF01490.13 EEQ28743.1 - 2.2e-26 92.2 34.4 4.2e-26 91.3 23.8 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein GCV_T PF01571.16 EEQ28744.1 - 2.5e-55 187.0 0.0 4.4e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EEQ28744.1 - 1.4e-19 69.8 0.2 2.5e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain APS_kinase PF01583.15 EEQ28745.1 - 3.9e-59 198.7 0.2 5.8e-58 194.9 0.0 2.4 2 1 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.1 EEQ28745.1 - 1.3e-05 25.0 0.2 0.00016 21.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEQ28745.1 - 0.00011 22.4 0.1 0.00047 20.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEQ28745.1 - 0.00082 20.1 0.0 0.002 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEQ28745.1 - 0.005 16.3 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain PhoH PF02562.11 EEQ28745.1 - 0.0097 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein ABC_tran PF00005.22 EEQ28745.1 - 0.011 15.9 0.1 0.11 12.7 0.0 2.2 2 1 0 2 2 2 0 ABC transporter CbiA PF01656.18 EEQ28745.1 - 0.048 13.0 0.9 0.09 12.1 0.6 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EEQ28745.1 - 0.05 13.5 6.4 0.064 13.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.5 EEQ28745.1 - 0.12 11.6 0.2 0.5 9.5 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 V-ATPase_C PF03223.10 EEQ28746.1 - 1.7e-120 402.3 0.0 1.9e-120 402.2 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 EEQ28746.1 - 0.082 13.2 0.5 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain 4HBT PF03061.17 EEQ28747.1 - 2e-11 43.8 0.0 3.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Ligase_CoA PF00549.14 EEQ28748.1 - 2.2e-34 118.2 2.1 4.6e-17 62.0 0.1 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EEQ28748.1 - 8.7e-17 61.4 1.1 2.8e-16 59.8 0.1 2.2 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EEQ28748.1 - 1.6e-09 37.5 0.1 1e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EEQ28748.1 - 0.0093 16.1 0.1 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain E1-E2_ATPase PF00122.15 EEQ28750.1 - 2e-60 203.7 2.0 3.1e-60 203.0 1.4 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EEQ28750.1 - 2.3e-21 75.5 0.0 4.3e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEQ28750.1 - 3.3e-06 26.4 0.2 1.3e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus YjgP_YjgQ PF03739.9 EEQ28750.1 - 0.001 17.9 2.4 0.017 13.9 2.7 1.9 2 0 0 2 2 2 1 Predicted permease YjgP/YjgQ family Hydrolase PF00702.21 EEQ28750.1 - 0.0016 18.8 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2976 PF11190.3 EEQ28750.1 - 0.8 9.2 11.6 0.51 9.9 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Nup84_Nup100 PF04121.8 EEQ28751.1 - 8.1e-62 208.9 0.2 9.4e-61 205.3 0.2 2.4 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nop14 PF04147.7 EEQ28751.1 - 0.2 9.5 17.1 0.33 8.8 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EEQ28751.1 - 6.3 5.1 16.2 12 4.2 11.3 1.4 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 EEQ28751.1 - 9.6 4.4 25.6 15 3.8 17.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1903 PF08991.5 EEQ28752.1 - 3.4e-17 62.3 11.3 3.3e-15 55.9 2.4 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1903) CHCH PF06747.8 EEQ28752.1 - 0.021 14.7 2.0 0.041 13.8 1.4 1.5 1 0 0 1 1 1 0 CHCH domain Rad60-SLD PF11976.3 EEQ28753.1 - 7.5e-21 73.6 0.3 9.2e-21 73.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EEQ28753.1 - 5.5e-09 35.3 0.2 6.8e-09 35.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EEQ28753.1 - 0.072 12.8 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Abhydrolase_6 PF12697.2 EEQ28755.1 - 1.8e-11 44.3 0.1 2.3e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ28755.1 - 8.5e-07 28.8 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EEQ28755.1 - 0.055 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Methyltransf_25 PF13649.1 EEQ28756.1 - 7.6e-12 45.4 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ28756.1 - 7.5e-08 32.2 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ28756.1 - 5.4e-06 26.8 0.0 8.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ28756.1 - 7.6e-06 25.5 0.0 9.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ28756.1 - 2e-05 24.9 0.0 3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ28756.1 - 0.00071 20.1 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ28756.1 - 0.0036 16.4 0.0 0.0049 16.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEQ28756.1 - 0.084 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Isochorismatase PF00857.15 EEQ28757.1 - 1.9e-35 122.3 0.0 5.1e-35 120.9 0.0 1.7 2 0 0 2 2 2 1 Isochorismatase family Iso_dh PF00180.15 EEQ28757.1 - 2.4e-10 39.9 0.0 7.2e-07 28.4 0.0 2.3 2 1 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Methyltransf_31 PF13847.1 EEQ28759.1 - 5e-12 45.6 0.0 6.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ28759.1 - 9.1e-11 41.7 0.0 1.2e-10 41.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ28759.1 - 2.2e-10 40.8 0.0 4.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ28759.1 - 1.1e-08 35.5 0.0 3.2e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ28759.1 - 5.8e-07 29.9 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ28759.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ28759.1 - 0.022 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ28759.1 - 0.081 12.0 0.0 0.23 10.5 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.13 EEQ28759.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain AGT PF11440.3 EEQ28760.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Aldedh PF00171.17 EEQ28761.1 - 6e-108 361.1 0.0 7.4e-108 360.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tubulin PF00091.20 EEQ28762.1 - 4.5e-70 235.8 0.0 7.2e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEQ28762.1 - 1.8e-49 166.9 0.2 3.1e-49 166.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EEQ28762.1 - 1e-06 28.7 0.0 2.7e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EEQ28762.1 - 0.006 16.0 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 EEQ28763.1 - 2.6e-16 59.0 0.1 2.1e-07 30.4 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ28763.1 - 1.7e-14 53.5 0.0 4.7e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ28763.1 - 4.2e-12 45.7 0.1 2.5e-08 33.6 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.5 EEQ28763.1 - 0.32 10.7 1.8 2.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Pkinase PF00069.20 EEQ28764.1 - 1.7e-65 220.7 0.0 3e-65 219.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28764.1 - 7.2e-35 120.2 0.0 1.4e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ28764.1 - 2.2e-08 33.4 0.0 7.2e-08 31.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ28764.1 - 0.00028 20.6 2.1 0.0035 17.1 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEQ28764.1 - 0.0086 14.9 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EEQ28764.1 - 0.087 12.1 0.3 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 RIO1 family adh_short PF00106.20 EEQ28765.1 - 2.6e-14 53.4 0.3 4.3e-14 52.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase TPR_6 PF13174.1 EEQ28766.1 - 0.00039 20.7 0.7 1.3 9.6 0.1 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ28766.1 - 0.032 14.5 2.0 0.49 10.7 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-UBR PF02207.15 EEQ28766.1 - 0.51 10.0 3.8 1 9.1 2.7 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) VWA_3 PF13768.1 EEQ28768.1 - 3.8e-24 85.1 0.0 6.6e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EEQ28768.1 - 1.1e-20 73.4 0.0 2.1e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EEQ28768.1 - 2.6e-09 37.4 0.0 5.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EEQ28768.1 - 7.8e-07 28.9 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EEQ28768.1 - 3.5e-06 26.3 0.0 8.9e-06 25.0 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EEQ28768.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.4 EEQ28768.1 - 0.0062 16.5 0.0 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 VWA-like domain (DUF2201) MU117 PF15474.1 EEQ28769.1 - 3.8e-18 65.7 11.0 4.9e-18 65.4 7.6 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family Kp4 PF09044.5 EEQ28769.1 - 0.23 11.2 9.5 0.47 10.2 6.6 1.5 1 1 0 1 1 1 0 Kp4 CAP59_mtransfer PF11735.3 EEQ28770.1 - 8.5e-71 237.9 0.0 1.2e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 LANC_like PF05147.8 EEQ28771.1 - 1.1e-20 73.4 0.0 1.8e-17 62.9 0.0 3.2 2 1 0 2 2 2 2 Lanthionine synthetase C-like protein CBF PF03914.12 EEQ28772.1 - 1.2e-49 167.9 1.6 2.5e-49 166.8 0.1 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Prok-E2_C PF14459.1 EEQ28772.1 - 0.036 14.1 0.0 0.097 12.7 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family C tRNA-synt_2b PF00587.20 EEQ28773.1 - 1.1e-32 112.9 0.0 1.7e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ28773.1 - 3.4e-10 39.7 0.0 8.9e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Prefoldin PF02996.12 EEQ28774.1 - 2e-22 79.1 0.0 2.7e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit YscO PF07321.7 EEQ28774.1 - 0.13 12.0 0.1 11 5.8 0.0 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO KH_3 PF13014.1 EEQ28775.1 - 0.0089 15.6 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 EEQ28775.1 - 0.072 12.7 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 KH domain CHCH PF06747.8 EEQ28776.1 - 1.1e-05 25.2 16.3 0.00027 20.7 7.2 2.4 2 0 0 2 2 2 2 CHCH domain Pet191_N PF10203.4 EEQ28776.1 - 0.016 15.2 8.9 0.074 13.1 1.1 2.9 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EEQ28776.1 - 0.31 11.0 11.8 2.8 8.0 4.4 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EEQ28776.1 - 1.7 8.4 14.3 7.7 6.3 0.5 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CAP PF00188.21 EEQ28777.1 - 2.2e-20 73.3 8.4 2.8e-20 73.0 5.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FAP PF07174.6 EEQ28777.1 - 2.2 7.5 38.2 3.2 6.9 26.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Thioredox_DsbH PF03190.10 EEQ28778.1 - 3.6e-68 228.3 0.0 1.1e-67 226.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EEQ28778.1 - 1.4e-05 25.0 0.0 6.1e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like Glyco_hydro_9 PF00759.14 EEQ28778.1 - 0.017 14.0 0.1 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Glyco_hydro_76 PF03663.9 EEQ28778.1 - 0.097 12.0 0.2 0.86 8.9 0.1 2.0 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 WD40 PF00400.27 EEQ28779.1 - 4.3e-25 86.6 14.1 8.4e-06 25.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Reg_prop PF07494.6 EEQ28779.1 - 0.005 16.7 0.1 0.87 9.8 0.0 3.4 3 0 0 3 3 3 1 Two component regulator propeller Nup160 PF11715.3 EEQ28779.1 - 0.022 12.9 0.0 0.18 9.8 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEQ28779.1 - 0.025 13.3 0.1 0.12 11.0 0.0 2.1 1 1 0 1 1 1 0 Nup133 N terminal like DUF1902 PF08972.6 EEQ28779.1 - 0.071 12.6 1.2 0.99 9.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) PQQ_3 PF13570.1 EEQ28779.1 - 0.12 12.7 0.4 1.5 9.1 0.0 3.0 3 1 0 3 3 3 0 PQQ-like domain LSM14 PF12701.2 EEQ28780.1 - 1.5e-31 108.0 0.0 3.4e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EEQ28780.1 - 2.1e-17 63.5 5.8 2.1e-17 63.5 4.0 3.1 3 1 0 3 3 3 1 FDF domain SM-ATX PF14438.1 EEQ28780.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 2 0 Ataxin 2 SM domain GRP PF07172.6 EEQ28780.1 - 3.9 8.0 26.0 16 6.0 12.5 2.7 2 0 0 2 2 2 0 Glycine rich protein family ACBP PF00887.14 EEQ28781.1 - 2.4e-28 97.6 0.4 1.1e-27 95.5 0.0 2.3 3 0 0 3 3 2 1 Acyl CoA binding protein PPP4R2 PF09184.6 EEQ28781.1 - 0.012 15.1 7.5 0.019 14.5 5.2 1.3 1 0 0 1 1 1 0 PPP4R2 GP41 PF00517.12 EEQ28781.1 - 0.015 14.8 1.6 0.015 14.8 1.1 1.5 2 0 0 2 2 2 0 Retroviral envelope protein Nucleoplasmin PF03066.10 EEQ28781.1 - 0.024 14.1 7.2 0.035 13.6 5.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2628 PF10947.3 EEQ28781.1 - 0.026 14.3 0.1 0.045 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) CDC45 PF02724.9 EEQ28781.1 - 0.038 12.0 3.2 0.046 11.7 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TraP PF07296.6 EEQ28781.1 - 0.11 11.3 0.8 0.2 10.5 0.6 1.3 1 0 0 1 1 1 0 TraP protein Sigma70_ner PF04546.8 EEQ28781.1 - 0.48 10.0 9.6 0.36 10.4 5.3 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Daxx PF03344.10 EEQ28781.1 - 0.72 8.2 12.7 0.94 7.8 8.8 1.2 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 EEQ28781.1 - 1.1 7.0 4.2 1.4 6.6 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LZ_Tnp_IS66 PF13007.2 EEQ28781.1 - 1.4 9.6 10.5 0.11 13.2 3.7 1.9 2 0 0 2 2 1 0 Transposase C of IS166 homeodomain Pox_Ag35 PF03286.9 EEQ28781.1 - 1.8 8.0 5.7 3 7.3 4.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2890 PF11081.3 EEQ28781.1 - 2 8.4 19.8 0.081 12.9 8.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) RXT2_N PF08595.6 EEQ28781.1 - 2.7 7.7 6.5 5 6.9 4.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Glyco_transf_15 PF01793.11 EEQ28782.1 - 6.7e-139 462.4 8.4 8.1e-139 462.1 5.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 EEQ28783.1 - 1.2e-65 221.9 11.6 1.5e-65 221.5 8.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GATase_5 PF13507.1 EEQ28784.1 - 3.4e-95 317.8 0.0 5.8e-95 317.0 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EEQ28784.1 - 6.1e-45 152.9 0.3 2.5e-21 76.3 0.1 2.6 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EEQ28784.1 - 2.8e-26 91.5 0.0 5e-25 87.5 0.0 2.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain MFS_1 PF07690.11 EEQ28785.1 - 1.2e-38 132.7 26.6 1.2e-38 132.7 18.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ28785.1 - 5.9e-07 28.0 3.9 8.5e-07 27.5 1.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EEQ28785.1 - 0.057 11.4 5.1 0.86 7.5 0.1 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family zf-C3H1 PF10650.4 EEQ28786.1 - 4.2e-06 26.1 0.1 7.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Myosin_head PF00063.16 EEQ28787.1 - 1.2e-239 796.9 0.0 1.2e-239 796.9 0.0 2.4 2 1 1 3 3 3 1 Myosin head (motor domain) Isy1 PF06246.7 EEQ28787.1 - 4.2e-83 278.6 0.1 4.2e-83 278.6 0.1 8.8 4 2 2 7 7 7 1 Isy1-like splicing family Myosin_tail_1 PF01576.14 EEQ28787.1 - 1.2e-32 112.6 271.4 1.3e-23 82.6 53.4 6.0 3 2 2 5 5 5 4 Myosin tail Myosin_N PF02736.14 EEQ28787.1 - 0.00031 20.3 0.2 0.00083 18.9 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ADIP PF11559.3 EEQ28787.1 - 0.0039 17.0 13.1 0.0039 17.0 9.1 17.5 5 3 12 18 18 18 2 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EEQ28787.1 - 0.041 13.0 82.5 0.12 11.5 3.9 9.7 4 3 4 10 10 10 0 Reovirus sigma C capsid protein AAA_19 PF13245.1 EEQ28787.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 EEQ28788.1 - 1e-12 48.0 0.1 1.7e-12 47.3 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEQ28788.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EEQ28788.1 - 0.00034 19.9 0.2 0.00097 18.4 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 EEQ28788.1 - 0.0023 17.6 0.1 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EEQ28788.1 - 0.0099 15.3 0.0 0.04 13.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EEQ28788.1 - 0.0099 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ28788.1 - 0.02 15.7 0.0 0.044 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEQ28788.1 - 0.029 14.5 0.0 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EEQ28788.1 - 0.037 12.8 0.1 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 EEQ28788.1 - 0.039 14.4 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 EEQ28788.1 - 0.058 12.4 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.18 EEQ28788.1 - 0.1 12.4 0.1 2.3 8.0 0.0 2.3 1 1 1 2 2 2 0 Dynamin family AAA_15 PF13175.1 EEQ28788.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.16 EEQ28788.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family NTPase_1 PF03266.10 EEQ28788.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 NTPase HCO3_cotransp PF00955.16 EEQ28789.1 - 2e-48 165.3 15.3 3.9e-26 91.8 0.8 2.1 1 1 1 2 2 2 2 HCO3- transporter family PI3Ka PF00613.15 EEQ28790.1 - 2e-59 199.9 0.2 3.2e-59 199.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EEQ28790.1 - 2e-43 148.5 0.0 1.4e-41 142.5 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EEQ28790.1 - 5.2e-29 100.8 0.0 8.2e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 EEQ28791.1 - 1.9e-33 114.3 0.0 7.9e-33 112.3 0.0 2.1 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EEQ28791.1 - 4e-17 61.7 0.1 1.5e-16 59.9 0.0 2.0 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Aida_N PF08910.5 EEQ28791.1 - 0.27 11.5 1.7 1.1 9.4 0.0 2.5 3 0 0 3 3 3 0 Aida N-terminus DUF4336 PF14234.1 EEQ28792.1 - 3.1e-17 62.6 0.2 4.8e-14 52.2 0.0 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF4336) MARVEL PF01284.18 EEQ28794.1 - 1.7e-17 63.5 10.0 2.1e-17 63.2 6.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.1 EEQ28794.1 - 0.22 10.8 2.6 0.47 9.7 1.9 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Metallophos PF00149.23 EEQ28795.1 - 4.9e-12 45.6 0.0 7.7e-11 41.7 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ28795.1 - 2.5e-09 37.1 0.0 4.8e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EEQ28795.1 - 0.046 12.8 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily ThiF PF00899.16 EEQ28796.1 - 1.9e-36 124.8 0.0 3.5e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 EEQ28796.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_17 PF00332.13 EEQ28796.1 - 0.023 13.7 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 ApbA PF02558.11 EEQ28796.1 - 0.024 14.0 0.0 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EEQ28796.1 - 0.079 11.9 1.4 0.56 9.1 1.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EEQ28796.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.15 EEQ28797.1 - 1.8e-18 66.9 0.0 9e-18 64.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ28797.1 - 2.9e-09 37.1 0.0 1.8e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EEQ28797.1 - 0.0007 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Gly_transf_sug PF04488.10 EEQ28799.1 - 1.2e-12 48.1 0.0 2.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Trypan_PARP PF05887.6 EEQ28799.1 - 0.00089 19.0 7.3 0.0014 18.4 5.0 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 EEQ28799.1 - 0.6 9.1 5.7 0.82 8.7 3.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pkinase PF00069.20 EEQ28800.1 - 3.4e-62 209.9 0.0 4e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28800.1 - 5.5e-34 117.4 0.0 7e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ28800.1 - 0.00015 20.8 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EEQ28800.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EEQ28800.1 - 0.017 14.2 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ28800.1 - 0.036 13.8 0.1 0.071 12.8 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family ATP-synt_C PF00137.16 EEQ28801.1 - 1.9e-17 62.9 30.4 1.5e-15 56.7 7.0 2.9 2 1 0 2 2 2 2 ATP synthase subunit C CNH PF00780.17 EEQ28802.1 - 6e-71 239.0 0.0 1.6e-51 175.3 0.0 2.9 2 1 1 3 3 3 2 CNH domain PH_5 PF15405.1 EEQ28802.1 - 8.8e-39 132.5 0.0 2.1e-38 131.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EEQ28802.1 - 2.4e-38 131.8 0.0 4.2e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EEQ28802.1 - 4.9e-13 48.6 0.0 1.1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Septin PF00735.13 EEQ28803.1 - 3.5e-100 334.6 0.3 6.3e-100 333.8 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EEQ28803.1 - 0.0025 17.7 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEQ28803.1 - 0.014 15.1 2.7 0.47 10.2 0.0 3.0 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.22 EEQ28803.1 - 0.025 13.9 0.0 0.5 9.7 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF390 PF04094.9 EEQ28803.1 - 0.036 12.1 6.3 0.11 10.5 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF390) FMN_bind PF04205.9 EEQ28803.1 - 0.24 11.5 0.8 0.69 10.1 0.0 2.0 2 0 0 2 2 2 0 FMN-binding domain DUF3653 PF12375.3 EEQ28803.1 - 0.32 11.2 2.3 7.4 6.8 0.8 2.8 2 1 0 2 2 2 0 Phage protein WD40 PF00400.27 EEQ28804.1 - 5.9e-08 32.3 0.1 0.00074 19.3 0.1 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Nbas_N PF15492.1 EEQ28804.1 - 0.14 11.2 0.0 1.8 7.6 0.0 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.17 EEQ28805.1 - 6e-20 70.6 0.5 2.2e-19 68.8 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ28805.1 - 5.4e-14 51.9 0.0 1.2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ28805.1 - 3.5e-06 26.7 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3006 PF11213.3 EEQ28805.1 - 0.027 14.1 0.0 3 7.6 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3006) DLIC PF05783.6 EEQ28806.1 - 7.9e-31 107.2 1.6 2.5e-19 69.3 0.0 3.9 4 0 0 4 4 4 3 Dynein light intermediate chain (DLIC) Myb_CC_LHEQLE PF14379.1 EEQ28806.1 - 0.056 13.0 4.8 0.13 11.8 3.3 1.5 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif Peptidase_S9 PF00326.16 EEQ28807.1 - 1.5e-48 164.8 0.3 3.1e-48 163.8 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ28807.1 - 2.3e-07 30.6 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EEQ28807.1 - 5.6e-07 29.0 0.1 0.4 10.4 0.0 4.1 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat APH PF01636.18 EEQ28808.1 - 6.5e-15 55.5 0.0 1.2e-14 54.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ28808.1 - 0.00096 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ28808.1 - 0.046 12.8 0.0 3.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 EEQ28808.1 - 0.052 12.1 0.0 0.42 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Peptidase_C12 PF01088.16 EEQ28809.1 - 5e-55 185.9 0.0 6e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EEQ28809.1 - 0.025 15.1 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Y_phosphatase3 PF13350.1 EEQ28810.1 - 9.4e-48 162.5 0.0 1.2e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EEQ28810.1 - 0.00024 21.1 0.2 0.008 16.2 0.0 2.5 2 1 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EEQ28810.1 - 0.0055 16.0 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EEQ28810.1 - 0.006 15.9 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EEQ28810.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Spermine_synth PF01564.12 EEQ28811.1 - 0.07 12.0 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase Methyltransf_30 PF05430.6 EEQ28811.1 - 0.098 12.3 0.0 0.37 10.4 0.0 1.8 1 1 1 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase DUF2052 PF09747.4 EEQ28812.1 - 2.8e-31 108.8 13.1 1.2e-30 106.8 9.1 1.8 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) tRNA-synt_1d PF00750.14 EEQ28813.1 - 3.7e-50 170.7 0.0 1e-49 169.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EEQ28813.1 - 5.5e-30 103.7 1.0 8.1e-30 103.2 0.1 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain GST_N PF02798.15 EEQ28814.1 - 1.6e-09 37.7 0.0 2.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEQ28814.1 - 4e-09 36.5 0.1 7.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ28814.1 - 2.3e-07 30.7 0.0 4.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ28814.1 - 4.7e-07 29.6 0.0 7.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ28814.1 - 2e-05 24.9 0.0 3.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ28814.1 - 5e-05 23.0 0.0 9.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Response_reg PF00072.19 EEQ28815.1 - 2.2e-21 75.9 0.0 9.2e-14 51.4 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain SH3_1 PF00018.23 EEQ28817.1 - 2.5e-09 36.3 1.0 2.9e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEQ28817.1 - 2.3e-07 30.2 0.0 4.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ28817.1 - 5.4e-07 29.0 0.0 1.5e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TMEM220 PF15071.1 EEQ28817.1 - 5.4 7.5 7.4 7.3 7.0 2.7 2.5 1 1 1 2 2 2 0 Transmembrane family 220, helix UBA_4 PF14555.1 EEQ28819.1 - 5.7e-13 48.1 0.2 1.1e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain DUF2051 PF09738.4 EEQ28819.1 - 0.0015 17.8 0.8 0.013 14.8 0.1 2.1 2 0 0 2 2 2 1 Double stranded RNA binding protein (DUF2051) FlgN PF05130.7 EEQ28819.1 - 0.057 13.6 2.0 0.073 13.3 0.0 2.1 3 0 0 3 3 3 0 FlgN protein AMP-binding PF00501.23 EEQ28820.1 - 9e-58 195.6 0.0 1.6e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ28820.1 - 7.3e-11 42.8 0.3 2.3e-10 41.2 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 EEQ28821.1 - 3e-57 193.7 0.0 4.3e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28821.1 - 4.8e-26 91.3 0.0 1.4e-25 89.9 0.0 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ28821.1 - 0.0019 17.2 0.0 0.0037 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Bot1p PF12298.3 EEQ28823.1 - 2.2e-57 193.7 0.3 2.2e-57 193.7 0.2 1.6 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein DUF2361 PF10153.4 EEQ28823.1 - 0.84 9.8 5.8 0.89 9.7 0.8 2.7 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2361) RRM_1 PF00076.17 EEQ28824.1 - 1.7e-17 62.7 0.0 3e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ28824.1 - 4.2e-13 49.0 0.0 6.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EEQ28824.1 - 6.8e-08 32.8 3.9 6.8e-08 32.8 2.7 4.1 4 0 0 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EEQ28824.1 - 2.9e-07 30.2 0.0 4.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EEQ28825.1 - 2.2e-28 97.0 7.4 1.8e-09 37.0 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Cap_synth_GfcB PF11102.3 EEQ28825.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Group 4 capsule polysaccharide formation lipoprotein gfcB PUL PF08324.6 EEQ28826.1 - 2.6e-55 187.1 0.0 3.6e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EEQ28826.1 - 1.4e-43 147.6 0.3 1.1e-42 144.6 0.1 2.3 1 1 1 2 2 2 2 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EEQ28826.1 - 7.2e-40 133.4 20.0 9.4e-09 34.8 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat Rotamase_2 PF13145.1 EEQ28826.1 - 0.095 13.3 1.3 0.43 11.2 0.0 2.4 2 1 0 2 2 2 0 PPIC-type PPIASE domain YjeF_N PF03853.10 EEQ28827.1 - 4.5e-38 130.4 0.0 5.4e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 EEQ28828.1 - 5.7e-24 83.6 0.1 8.7e-24 83.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 DUF1950 PF09187.5 EEQ28829.1 - 0.026 14.6 0.1 0.065 13.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function(DUF1950) Pox_RNA_pol PF03293.9 EEQ28829.1 - 0.17 11.3 1.9 0.37 10.2 1.3 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit CarbpepA_inh PF02977.10 EEQ28829.1 - 2.9 7.5 10.0 2.9 7.5 0.1 2.6 2 1 0 2 2 2 0 Carboxypeptidase A inhibitor RRM_1 PF00076.17 EEQ28830.1 - 4.1e-15 55.1 0.0 3.6e-13 48.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ28830.1 - 2.2e-08 33.9 0.0 1.5e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ28830.1 - 0.14 12.0 0.1 5 7.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CH PF00307.26 EEQ28831.1 - 9.8e-33 112.4 0.2 1.3e-19 70.1 0.0 3.3 2 1 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EEQ28831.1 - 6.5e-27 93.3 0.2 1.7e-26 91.9 0.1 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EEQ28831.1 - 1.7e-09 37.1 0.6 7.2e-08 31.9 0.0 3.0 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_8 PF13833.1 EEQ28831.1 - 0.0025 17.3 0.1 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ28831.1 - 0.0027 17.4 0.0 0.018 14.8 0.0 2.5 1 0 0 1 1 1 1 EF-hand domain Spectrin PF00435.16 EEQ28831.1 - 0.016 15.4 10.0 0.88 9.8 0.0 2.9 3 0 0 3 3 3 0 Spectrin repeat EF-hand_1 PF00036.27 EEQ28831.1 - 0.02 14.1 0.1 0.18 11.1 0.0 2.5 2 0 0 2 2 2 0 EF hand G-alpha PF00503.15 EEQ28833.1 - 4e-129 430.7 1.6 4.9e-129 430.4 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEQ28833.1 - 1.4e-15 57.0 1.1 2e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EEQ28833.1 - 7.3e-05 22.2 0.0 0.00031 20.2 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EEQ28833.1 - 0.00099 19.5 0.1 1.8 9.1 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EEQ28833.1 - 0.0043 16.2 3.4 0.13 11.3 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EEQ28833.1 - 0.012 15.1 0.1 0.036 13.6 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EEQ28833.1 - 0.014 14.8 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ28833.1 - 0.096 12.6 0.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mog1 PF04603.7 EEQ28833.1 - 0.11 12.3 0.2 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Ran-interacting Mog1 protein FtsK_SpoIIIE PF01580.13 EEQ28833.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Use1 PF09753.4 EEQ28834.1 - 2.9e-09 36.7 1.8 1.2e-08 34.7 1.2 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF3692 PF12469.3 EEQ28834.1 - 0.12 12.6 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 CRISPR-associated protein DUF892 PF05974.7 EEQ28834.1 - 0.28 10.9 2.1 0.46 10.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Acetyltransf_1 PF00583.19 EEQ28835.1 - 7.3e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ28835.1 - 5.1e-06 26.5 0.0 1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ28835.1 - 5.5e-05 23.2 0.0 0.00013 22.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MIP-T3 PF10243.4 EEQ28836.1 - 0.059 11.8 5.8 0.064 11.7 4.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AMP-binding PF00501.23 EEQ28839.1 - 9.3e-87 291.0 0.0 1.2e-86 290.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ28839.1 - 1.2e-12 48.6 0.0 2.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nup188 PF10487.4 EEQ28840.1 - 7.7e-54 182.9 1.2 2.6e-52 177.9 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF465 PF04325.8 EEQ28840.1 - 0.095 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) SymE_toxin PF08845.5 EEQ28840.1 - 0.16 11.8 0.1 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 Toxin SymE, type I toxin-antitoxin system IGPS PF00218.16 EEQ28841.1 - 1.3e-96 322.5 0.0 7.9e-96 319.9 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EEQ28841.1 - 1.3e-52 178.2 0.6 3.3e-49 167.1 0.1 2.4 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EEQ28841.1 - 6.1e-51 172.6 0.0 1e-50 171.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEQ28841.1 - 0.00029 20.3 0.0 0.00072 19.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 His_biosynth PF00977.16 EEQ28841.1 - 0.0036 16.6 0.2 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein QRPTase_C PF01729.14 EEQ28841.1 - 0.0057 16.2 1.3 0.084 12.4 0.0 2.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 EEQ28841.1 - 0.0064 15.4 0.2 0.04 12.8 0.0 2.3 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase BRCT PF00533.21 EEQ28842.1 - 8.1e-08 32.3 0.1 1.5e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEQ28842.1 - 1.2e-07 31.4 0.1 2.6e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain WGR PF05406.10 EEQ28842.1 - 0.046 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 WGR domain UPF1_Zn_bind PF09416.5 EEQ28843.1 - 1.7e-66 222.4 4.5 4e-66 221.3 0.7 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EEQ28843.1 - 8.1e-59 198.3 0.0 1.3e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ28843.1 - 3.8e-56 190.3 2.8 5.9e-56 189.6 2.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ28843.1 - 2.3e-13 49.6 0.4 6.3e-13 48.2 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ28843.1 - 1.1e-10 41.4 0.3 1.9e-09 37.4 0.2 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EEQ28843.1 - 1.3e-08 34.9 0.0 2.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EEQ28843.1 - 0.00016 21.3 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 EEQ28843.1 - 0.0023 16.9 1.7 0.0076 15.2 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EEQ28843.1 - 0.014 14.8 0.3 0.033 13.6 0.2 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase PIF1 PF05970.9 EEQ28843.1 - 0.022 13.7 0.0 4.8 6.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase UvrD-helicase PF00580.16 EEQ28843.1 - 0.022 14.0 0.0 0.24 10.6 0.0 2.2 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain Ribosomal_S13_N PF08069.7 EEQ28843.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.1 EEQ28843.1 - 0.037 14.1 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EEQ28843.1 - 0.053 12.7 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 EEQ28843.1 - 0.078 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TFIIF_alpha PF05793.7 EEQ28843.1 - 0.08 11.2 2.4 0.16 10.3 1.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UvrD_C_2 PF13538.1 EEQ28843.1 - 0.14 12.2 0.0 0.52 10.4 0.0 2.0 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain T2SE PF00437.15 EEQ28843.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EEQ28843.1 - 0.21 10.6 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 KaiC zf-BED PF02892.10 EEQ28843.1 - 0.25 11.1 3.5 0.33 10.7 1.3 2.0 2 0 0 2 2 1 0 BED zinc finger PBP1_TM PF14812.1 EEQ28843.1 - 0.27 11.5 4.2 0.63 10.3 2.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Brix PF04427.13 EEQ28844.1 - 7.8e-47 159.4 0.1 9.7e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain AhpC-TSA_2 PF13911.1 EEQ28845.1 - 7.6e-12 45.1 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EEQ28845.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family PI-PLC-X PF00388.14 EEQ28846.1 - 9.6e-57 190.4 0.0 3e-56 188.8 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EEQ28846.1 - 4.1e-40 136.4 0.1 8.4e-40 135.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EEQ28846.1 - 3.7e-06 26.7 0.0 8.8e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 EEQ28846.1 - 7.8e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 EEQ28846.1 - 0.025 14.1 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair GDPD PF03009.12 EEQ28846.1 - 0.054 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_7 PF13499.1 EEQ28846.1 - 0.055 13.6 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair Mo-co_dimer PF03404.11 EEQ28849.1 - 3.1e-54 182.1 0.3 6e-54 181.1 0.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EEQ28849.1 - 1.5e-48 164.4 0.0 2.4e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.16 EEQ28849.1 - 1.3e-23 83.6 0.0 1e-22 80.7 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EEQ28849.1 - 1.2e-21 76.3 0.0 2.3e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 EEQ28849.1 - 1.3e-15 57.3 0.0 2.4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEQ28849.1 - 0.00058 19.7 0.0 0.0089 15.9 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Sec5 PF15469.1 EEQ28850.1 - 1.4e-34 119.4 0.1 1.1e-33 116.5 0.0 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EEQ28850.1 - 7.4e-05 22.5 0.3 0.00023 20.9 0.2 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Iso_dh PF00180.15 EEQ28851.1 - 7.7e-101 337.5 0.0 9.4e-101 337.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Eaf7 PF07904.8 EEQ28852.1 - 1.3e-24 85.9 0.0 2.3e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Spc97_Spc98 PF04130.8 EEQ28853.1 - 1.4e-63 215.0 0.1 1.7e-63 214.7 0.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family PGA_cap PF09587.5 EEQ28854.1 - 0.23 10.8 2.4 0.33 10.2 1.7 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF4210 PF13915.1 EEQ28855.1 - 2.1e-28 98.4 0.2 6.2e-27 93.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EEQ28855.1 - 5.4e-21 74.2 0.2 1.5e-20 72.8 0.1 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis CAP_N PF01213.14 EEQ28856.1 - 2e-79 267.1 0.0 3.4e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EEQ28856.1 - 5.2e-53 178.6 2.3 7.2e-53 178.1 1.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EEQ28856.1 - 0.016 14.5 3.7 0.3 10.5 2.1 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C DUF4041 PF13250.1 EEQ28856.1 - 0.08 12.5 0.2 4.5 6.9 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) PfkB PF00294.19 EEQ28857.1 - 3.3e-12 46.1 0.0 5.5e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribonucleas_3_3 PF14622.1 EEQ28859.1 - 6.4e-08 32.6 0.0 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EEQ28859.1 - 1.4e-06 28.6 0.0 2.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 EEQ28859.1 - 3.9e-05 24.1 0.0 7.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif ATP12 PF07542.6 EEQ28859.1 - 0.022 14.6 0.0 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 ATP12 chaperone protein WaaY PF06176.6 EEQ28860.1 - 0.027 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) 7kD_coat PF02495.12 EEQ28860.1 - 0.089 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 7kD viral coat protein BSP PF04450.7 EEQ28863.1 - 6.3e-64 215.2 0.0 7.3e-64 214.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EEQ28863.1 - 8.2e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EEQ28863.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 2 0 0 2 2 2 0 SprT-like family CLASP_N PF12348.3 EEQ28864.1 - 2.7e-150 498.0 3.5 5e-90 300.8 0.0 3.0 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EEQ28864.1 - 9.4e-07 28.4 0.3 2.3 8.5 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 EEQ28864.1 - 0.00021 21.1 0.1 0.01 15.6 0.0 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEQ28864.1 - 0.00042 20.5 2.8 0.012 15.8 0.1 4.4 5 1 1 6 6 6 1 HEAT repeats Acetyltransf_8 PF13523.1 EEQ28865.1 - 4.9e-43 146.6 1.9 7.3e-43 146.0 1.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEQ28865.1 - 0.03 14.4 0.1 0.049 13.7 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 EEQ28866.1 - 2.3e-75 253.5 34.3 5.1e-39 134.3 9.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ28866.1 - 5.4e-66 221.0 0.0 1.2e-32 113.0 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ28866.1 - 8e-17 61.2 1.9 4.9e-06 25.9 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EEQ28866.1 - 2.9e-11 42.6 0.8 0.00038 19.1 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EEQ28866.1 - 3.3e-10 39.3 0.1 0.00026 20.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EEQ28866.1 - 4.5e-10 39.9 0.7 0.0058 16.6 0.1 4.2 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EEQ28866.1 - 2e-09 38.3 0.0 0.00016 22.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ28866.1 - 1.1e-08 35.2 4.6 9.6e-05 22.4 0.5 3.1 2 1 1 3 3 3 2 AAA ATPase domain DUF87 PF01935.12 EEQ28866.1 - 3.6e-07 30.2 0.2 0.00089 19.1 0.0 2.9 3 0 0 3 3 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 EEQ28866.1 - 2.4e-06 27.7 1.4 0.16 12.1 0.2 4.0 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EEQ28866.1 - 8.7e-06 25.0 0.0 0.09 11.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEQ28866.1 - 1.5e-05 24.5 2.7 0.097 12.0 0.0 3.7 3 1 0 3 3 3 2 AAA-like domain AAA_25 PF13481.1 EEQ28866.1 - 2.6e-05 23.6 0.1 0.13 11.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EEQ28866.1 - 5.2e-05 23.5 0.1 0.089 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EEQ28866.1 - 0.0003 20.3 0.0 0.0073 15.8 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EEQ28866.1 - 0.00058 19.0 0.0 0.16 11.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 EEQ28866.1 - 0.00071 19.2 0.5 1.7 8.1 0.0 4.0 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 EEQ28866.1 - 0.001 18.9 2.8 1.2 9.1 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EEQ28866.1 - 0.001 18.9 0.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.4 EEQ28866.1 - 0.0011 17.6 0.2 0.91 8.0 0.0 2.8 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.1 EEQ28866.1 - 0.0014 19.0 3.7 1.2 9.4 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 EEQ28866.1 - 0.005 16.5 0.0 5 6.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EEQ28866.1 - 0.0069 15.8 0.1 0.71 9.2 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.9 EEQ28866.1 - 0.0077 15.9 0.0 4.3 7.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF3987 PF13148.1 EEQ28866.1 - 0.012 14.2 5.5 0.71 8.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_28 PF13521.1 EEQ28866.1 - 0.016 15.2 0.3 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EEQ28866.1 - 0.03 13.0 0.0 1.6 7.3 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 EEQ28866.1 - 0.044 13.7 0.1 13 5.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase COX5A PF02284.11 EEQ28867.1 - 9.1e-39 131.7 1.1 1.2e-38 131.3 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va CK2S PF15011.1 EEQ28867.1 - 0.081 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate ELO PF01151.13 EEQ28868.1 - 7e-63 212.2 18.9 8.4e-63 211.9 13.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family AA_permease_2 PF13520.1 EEQ28870.1 - 1.9e-18 66.2 37.7 2.3e-14 52.8 18.8 2.2 2 0 0 2 2 2 2 Amino acid permease adh_short_C2 PF13561.1 EEQ28871.1 - 3.2e-34 118.7 0.0 4.1e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ28871.1 - 9.7e-30 103.6 0.0 1.2e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ28871.1 - 2.4e-06 27.3 0.1 5.5e-06 26.1 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ28871.1 - 0.0035 16.7 0.2 0.0087 15.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HI0933_like PF03486.9 EEQ28871.1 - 0.085 11.3 0.5 0.11 10.8 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein Eno-Rase_NADH_b PF12242.3 EEQ28871.1 - 0.15 11.9 0.8 0.28 11.0 0.6 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1996 PF09362.5 EEQ28872.1 - 6.7e-79 264.8 0.0 9.1e-79 264.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.8 EEQ28872.1 - 0.026 14.6 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase 7tm_4 PF13853.1 EEQ28873.1 - 0.22 11.3 1.3 0.3 10.8 0.8 1.3 1 1 0 1 1 1 0 Olfactory receptor Y_phosphatase3 PF13350.1 EEQ28874.1 - 1.3e-31 110.0 0.0 9e-31 107.3 0.0 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EEQ28874.1 - 6.6e-07 29.3 0.0 2e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EEQ28874.1 - 4.7e-05 22.8 0.0 7.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EEQ28874.1 - 0.0038 16.5 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EEQ28874.1 - 0.04 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EEQ28874.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain ABC_tran PF00005.22 EEQ28875.1 - 6.7e-67 224.0 0.1 2.1e-33 115.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ28875.1 - 1e-44 153.0 28.8 5.4e-40 137.5 11.6 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEQ28875.1 - 1e-13 51.8 0.0 0.00095 19.2 0.0 4.4 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EEQ28875.1 - 3.1e-13 49.4 7.6 0.00012 21.4 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EEQ28875.1 - 1.9e-09 36.9 0.0 0.00089 18.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ28875.1 - 1.9e-09 37.7 0.4 0.0026 17.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEQ28875.1 - 1.5e-08 34.0 1.8 0.00043 19.7 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EEQ28875.1 - 3.5e-08 32.4 1.6 0.011 14.3 0.0 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EEQ28875.1 - 7e-07 30.0 0.0 0.034 14.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEQ28875.1 - 8.8e-07 29.1 2.3 0.11 12.6 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ28875.1 - 1.7e-06 27.6 0.0 0.043 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEQ28875.1 - 6e-05 22.9 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EEQ28875.1 - 0.0001 22.0 0.1 1.1 9.0 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA PF00004.24 EEQ28875.1 - 0.00018 21.7 1.1 0.8 9.9 0.1 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EEQ28875.1 - 0.00021 21.1 2.7 1.3 8.9 0.2 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EEQ28875.1 - 0.00047 20.0 0.2 0.061 13.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EEQ28875.1 - 0.0006 19.7 0.0 0.091 12.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.1 EEQ28875.1 - 0.00098 18.7 1.5 5.1 6.6 0.0 4.2 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EEQ28875.1 - 0.001 18.9 0.0 4.3 7.2 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EEQ28875.1 - 0.0014 18.9 0.0 1.6 9.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.8 EEQ28875.1 - 0.0017 17.3 0.0 0.7 8.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EEQ28875.1 - 0.0022 17.9 0.6 2.3 8.1 0.0 3.1 3 1 0 3 3 2 1 AAA domain MobB PF03205.9 EEQ28875.1 - 0.0023 17.6 0.1 0.57 9.8 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EEQ28875.1 - 0.003 18.0 0.0 0.29 11.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 EEQ28875.1 - 0.0046 17.1 0.0 0.4 10.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 EEQ28875.1 - 0.02 14.3 4.5 3.2 7.0 0.1 3.4 4 0 0 4 4 4 0 AAA-like domain G-alpha PF00503.15 EEQ28875.1 - 0.022 13.4 0.0 4.9 5.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.18 EEQ28875.1 - 0.046 13.5 0.8 0.45 10.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family CbiA PF01656.18 EEQ28875.1 - 0.046 13.1 0.0 12 5.2 0.0 3.3 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Septin PF00735.13 EEQ28875.1 - 0.051 12.5 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_23 PF13476.1 EEQ28875.1 - 0.26 11.6 5.5 7.6 6.7 0.4 2.5 2 0 0 2 2 2 0 AAA domain DUF3632 PF12311.3 EEQ28876.1 - 1.7e-37 129.0 0.0 2.1e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) KAR9 PF08580.5 EEQ28877.1 - 1.4 7.1 5.8 1.8 6.7 4.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 APH PF01636.18 EEQ28878.1 - 0.017 14.8 0.0 0.082 12.6 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family APH PF01636.18 EEQ28879.1 - 0.00013 21.8 0.0 0.16 11.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ28879.1 - 0.051 13.1 0.1 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Peptidase_S8 PF00082.17 EEQ28880.1 - 4e-43 147.5 0.8 5.9e-43 147.0 0.5 1.2 1 0 0 1 1 1 1 Subtilase family DUF796 PF05638.7 EEQ28880.1 - 0.14 12.2 0.2 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF796) 2-Hacid_dh_C PF02826.14 EEQ28881.1 - 7.7e-49 165.2 0.0 6.5e-48 162.2 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ28881.1 - 3.6e-14 52.3 0.0 4.7e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEQ28881.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEQ28881.1 - 0.00083 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 EEQ28881.1 - 0.15 12.3 0.0 1 9.6 0.0 2.2 2 1 0 2 2 2 0 XdhC Rossmann domain Asparaginase PF00710.15 EEQ28882.1 - 5.5e-105 350.6 0.0 6.8e-105 350.3 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EEQ28882.1 - 1.6e-11 44.3 0.0 3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ28882.1 - 9.3e-11 40.9 1.0 5.8e-05 22.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EEQ28882.1 - 2.1e-09 37.6 0.4 0.00023 21.6 0.0 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ28882.1 - 1.6e-08 34.5 0.1 1.8e-07 31.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ28882.1 - 2.6e-05 24.0 0.3 0.35 11.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat MTTB PF06253.6 EEQ28882.1 - 0.019 12.7 0.3 0.028 12.1 0.2 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) NmrA PF05368.8 EEQ28884.1 - 4.8e-07 29.2 0.2 5.5e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAP PF00956.13 EEQ28885.1 - 8.6e-30 103.6 7.2 8.6e-30 103.6 5.0 2.0 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) Syntaxin-6_N PF09177.6 EEQ28886.1 - 5.9e-23 81.1 1.5 5.6e-22 77.9 0.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EEQ28886.1 - 3.8e-12 45.7 3.9 3.8e-12 45.7 2.7 2.8 3 0 0 3 3 3 1 SNARE domain THOC7 PF05615.8 EEQ28886.1 - 0.013 15.7 3.9 0.066 13.4 0.1 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Vps51 PF08700.6 EEQ28886.1 - 0.021 14.6 5.0 3.2 7.6 0.1 3.2 3 0 0 3 3 3 0 Vps51/Vps67 PilJ PF13675.1 EEQ28886.1 - 0.033 14.5 1.5 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Reo_sigmaC PF04582.7 EEQ28886.1 - 0.046 12.8 0.3 0.73 8.9 0.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Syntaxin_2 PF14523.1 EEQ28886.1 - 0.08 12.9 0.5 0.91 9.5 0.0 2.5 2 1 0 2 2 2 0 Syntaxin-like protein DUF883 PF05957.8 EEQ28886.1 - 0.11 12.9 3.4 13 6.2 0.0 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Laminin_II PF06009.7 EEQ28886.1 - 0.12 12.1 0.9 2.9 7.6 0.1 2.5 2 1 0 2 2 2 0 Laminin Domain II AKNA PF12443.3 EEQ28886.1 - 0.18 11.8 1.8 1.1 9.3 0.0 2.6 2 1 0 2 2 2 0 AT-hook-containing transcription factor Snapin_Pallidin PF14712.1 EEQ28886.1 - 0.24 11.7 5.7 2.3 8.6 0.1 2.6 2 1 0 2 2 2 0 Snapin/Pallidin HTH_25 PF13413.1 EEQ28886.1 - 0.27 10.9 2.4 0.64 9.6 0.1 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain NPV_P10 PF05531.7 EEQ28886.1 - 0.56 10.4 8.2 1 9.6 0.6 3.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3618 PF12277.3 EEQ28886.1 - 0.67 10.0 11.8 1.3 9.1 1.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) TBPIP PF07106.8 EEQ28886.1 - 0.9 9.0 5.3 1.9 8.0 0.0 2.7 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4200 PF13863.1 EEQ28886.1 - 4.2 7.3 10.6 14 5.6 0.4 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) Microtub_assoc PF07989.6 EEQ28886.1 - 4.7 7.1 5.9 3 7.7 0.7 2.7 3 0 0 3 3 3 0 Microtubule associated TMF_DNA_bd PF12329.3 EEQ28886.1 - 5.9 6.7 8.5 11 5.8 0.1 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DegS PF05384.6 EEQ28886.1 - 8.9 5.5 9.4 2.5 7.2 0.9 2.8 2 1 0 2 2 2 0 Sensor protein DegS Methyltransf_32 PF13679.1 EEQ28887.1 - 7.1e-21 74.3 1.0 1.9e-20 72.9 0.7 1.7 1 1 0 1 1 1 1 Methyltransferase domain PTR2 PF00854.16 EEQ28888.1 - 7.4e-39 133.5 13.7 7.9e-24 84.1 5.1 2.1 2 0 0 2 2 2 2 POT family Amb_V_allergen PF03913.8 EEQ28888.1 - 0.46 10.2 4.4 0.15 11.7 0.9 1.7 2 0 0 2 2 2 0 Amb V Allergen LCCL PF03815.14 EEQ28889.1 - 2.7e-19 68.9 0.3 4.3e-19 68.2 0.2 1.3 1 0 0 1 1 1 1 LCCL domain Pkinase PF00069.20 EEQ28890.1 - 0.00057 19.1 0.0 0.00081 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28890.1 - 0.0059 15.7 0.0 0.0079 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2012 PF09430.5 EEQ28891.1 - 6.5e-24 84.1 0.0 9.3e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) AMP-binding PF00501.23 EEQ28892.1 - 6.8e-71 238.8 0.0 8.9e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Cys_Met_Meta_PP PF01053.15 EEQ28893.1 - 1e-140 468.4 0.0 1.6e-140 467.8 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEQ28893.1 - 9.8e-15 54.4 0.2 1.7e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EEQ28893.1 - 2.5e-09 36.5 0.1 3.6e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ28893.1 - 6.6e-08 31.6 0.0 1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEQ28893.1 - 1.7e-06 27.4 0.1 2.9e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EEQ28893.1 - 0.0096 14.4 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 EEQ28893.1 - 0.036 12.7 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Sulfotransfer_3 PF13469.1 EEQ28894.1 - 1.3e-08 35.9 0.1 1.8e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family AAA_17 PF13207.1 EEQ28894.1 - 0.067 14.0 0.0 0.11 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain MARVEL PF01284.18 EEQ28895.1 - 1.7e-17 63.5 18.3 2.1e-17 63.2 12.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain EF-hand_4 PF12763.2 EEQ28896.1 - 2e-38 130.2 0.0 8.1e-16 57.6 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EEQ28896.1 - 2.3e-11 43.6 0.1 7.2e-06 26.0 0.2 3.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EEQ28896.1 - 1.4e-06 27.1 0.1 0.018 14.2 0.0 5.2 5 0 0 5 5 5 1 EF hand UBA PF00627.26 EEQ28896.1 - 1.7e-06 27.7 0.1 3.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 EEQ28896.1 - 5.1e-05 22.8 2.3 15 5.7 0.0 6.1 6 0 0 6 6 6 0 EF-hand domain DUF812 PF05667.6 EEQ28896.1 - 0.00073 18.1 14.1 0.0013 17.3 9.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ERM PF00769.14 EEQ28896.1 - 0.0042 16.6 18.2 0.0042 16.6 12.6 1.9 2 0 0 2 2 2 1 Ezrin/radixin/moesin family EF-hand_8 PF13833.1 EEQ28896.1 - 0.0046 16.5 0.9 0.031 13.8 0.0 2.8 3 0 0 3 3 2 1 EF-hand domain pair Fib_alpha PF08702.5 EEQ28896.1 - 0.01 15.9 6.1 0.01 15.9 4.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Myosin_tail_1 PF01576.14 EEQ28896.1 - 0.018 12.7 30.4 0.19 9.3 8.4 2.1 1 1 1 2 2 2 0 Myosin tail CENP-F_leu_zip PF10473.4 EEQ28896.1 - 0.051 13.4 28.6 0.056 13.2 7.4 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 EEQ28896.1 - 0.081 12.6 28.4 0.027 14.2 7.1 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein BicD PF09730.4 EEQ28896.1 - 0.12 10.7 25.2 0.33 9.2 17.2 1.6 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF3584 PF12128.3 EEQ28896.1 - 0.29 8.4 27.5 0.41 7.9 19.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 EEQ28896.1 - 0.32 10.5 30.1 0.0074 15.9 13.1 2.2 1 1 2 3 3 3 0 IncA protein GAS PF13851.1 EEQ28896.1 - 0.37 9.9 27.9 0.86 8.7 13.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EEQ28896.1 - 0.48 9.4 26.5 0.011 14.7 11.7 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 EEQ28896.1 - 2.1 6.8 24.8 0.32 9.6 5.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein MbeD_MobD PF04899.7 EEQ28896.1 - 3.6 7.5 15.0 4.7 7.1 0.8 4.3 2 1 2 4 4 4 0 MbeD/MobD like Seryl_tRNA_N PF02403.17 EEQ28896.1 - 5.3 7.1 26.3 0.32 11.0 4.5 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3166 PF11365.3 EEQ28896.1 - 6.5 7.2 12.5 0.32 11.4 1.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3166) DUF1664 PF07889.7 EEQ28896.1 - 7 6.4 9.4 2.3 8.0 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) 4HB_MCP_1 PF12729.2 EEQ28896.1 - 9.5 5.5 13.4 6.7 6.0 6.3 2.4 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction Tubulin PF00091.20 EEQ28897.1 - 6e-66 222.3 0.0 9e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEQ28897.1 - 9.9e-47 158.1 0.1 1.9e-46 157.1 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EEQ28897.1 - 0.0077 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EEQ28897.1 - 0.02 14.5 0.0 0.07 12.7 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Pga1 PF10333.4 EEQ28898.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Peptidase_M24 PF00557.19 EEQ28899.1 - 1.1e-39 136.2 0.0 1.6e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EEQ28899.1 - 4.2e-22 79.0 0.0 4.2e-21 75.8 0.0 2.4 2 1 1 3 3 3 1 Creatinase/Prolidase N-terminal domain MEF2_binding PF09047.5 EEQ28900.1 - 0.17 11.5 0.7 0.77 9.4 0.2 2.3 2 0 0 2 2 2 0 MEF2 binding SOR_SNZ PF01680.12 EEQ28902.1 - 9.1e-110 365.1 5.4 9.1e-110 365.1 3.7 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EEQ28902.1 - 2.2e-09 36.7 7.3 1.3e-07 30.9 0.0 2.7 3 1 1 4 4 4 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EEQ28902.1 - 0.00063 19.0 0.4 0.01 15.1 0.0 2.6 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 EEQ28902.1 - 0.0033 16.3 0.4 0.35 9.6 0.0 2.4 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) IGPS PF00218.16 EEQ28902.1 - 0.0039 16.2 0.0 0.055 12.5 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EEQ28902.1 - 0.02 13.8 0.8 0.21 10.5 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.19 EEQ28902.1 - 0.032 13.6 0.1 0.36 10.1 0.0 2.2 1 1 2 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.12 EEQ28902.1 - 0.037 13.1 0.4 0.85 8.7 0.0 2.9 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI NMO PF03060.10 EEQ28902.1 - 0.23 10.5 5.2 0.17 10.9 0.2 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase Peptidase_S64 PF08192.6 EEQ28903.1 - 3.1e-06 25.8 0.0 4.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.1 EEQ28903.1 - 0.00055 19.9 0.0 0.002 18.1 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.16 EEQ28903.1 - 0.0021 17.4 0.2 0.0042 16.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S32 PF05579.8 EEQ28903.1 - 0.0028 16.6 0.1 0.0054 15.7 0.1 1.4 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin PF00089.21 EEQ28903.1 - 0.077 12.5 0.0 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Trypsin FUN14 PF04930.10 EEQ28904.1 - 1.9e-08 34.4 0.6 1e-07 32.1 0.4 1.9 1 1 0 1 1 1 1 FUN14 family ORC2 PF04084.9 EEQ28905.1 - 1.3e-79 267.4 0.0 7.2e-77 258.3 0.0 2.1 1 1 0 1 1 1 1 Origin recognition complex subunit 2 ArgJ PF01960.13 EEQ28906.1 - 1.9e-146 487.4 0.0 2.2e-146 487.2 0.0 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.15 EEQ28907.1 - 4.9e-97 324.9 8.6 6.2e-97 324.6 6.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EEQ28907.1 - 2.5e-18 65.2 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Phage_GP20 PF06810.6 EEQ28908.1 - 0.00027 20.3 12.9 0.00027 20.3 9.0 3.3 2 1 1 3 3 3 1 Phage minor structural protein GP20 DUF3287 PF11690.3 EEQ28908.1 - 0.22 11.6 4.5 0.42 10.7 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) DUF2422 PF10337.4 EEQ28908.1 - 0.24 10.1 5.0 0.05 12.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2422) Spc42p PF11544.3 EEQ28908.1 - 0.7 9.8 14.8 0.025 14.4 4.7 2.9 3 0 0 3 3 3 0 Spindle pole body component Spc42p PBP1_TM PF14812.1 EEQ28908.1 - 0.98 9.7 15.9 0.069 13.4 6.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF972 PF06156.8 EEQ28908.1 - 1.1 9.5 26.5 6.2 7.2 4.5 4.9 1 1 2 4 4 4 0 Protein of unknown function (DUF972) SlyX PF04102.7 EEQ28908.1 - 7.1 7.0 11.4 0.83 10.0 3.0 3.2 2 0 0 2 2 2 0 SlyX DUF1700 PF08006.6 EEQ28909.1 - 1.3 8.2 9.1 2.3 7.4 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) GFA PF04828.9 EEQ28910.1 - 7.1e-16 57.9 2.2 7.1e-16 57.9 1.5 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DNA_RNApol_7kD PF03604.8 EEQ28910.1 - 0.27 10.7 0.3 0.27 10.7 0.2 2.8 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.1 EEQ28910.1 - 0.4 9.9 3.4 0.2 10.9 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Cys_rich_CWC PF14375.1 EEQ28910.1 - 0.76 9.7 9.2 0.1 12.5 1.9 2.5 3 0 0 3 3 3 0 Cysteine-rich CWC NOB1_Zn_bind PF08772.6 EEQ28910.1 - 4.7 7.1 6.2 5.9 6.8 0.8 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like MUG113 PF13455.1 EEQ28911.1 - 1.3e-26 92.8 0.9 2.6e-26 91.8 0.6 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EEQ28911.1 - 3.2e-18 65.9 0.2 7.6e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain tRNA-synt_2c PF01411.14 EEQ28912.1 - 1.6e-08 33.3 0.0 2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EEQ28912.1 - 1.1e-05 25.1 0.4 1.9e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.11 EEQ28913.1 - 1.5e-49 168.5 31.9 7.5e-41 140.0 18.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EEQ28913.1 - 0.076 11.7 4.3 0.14 10.8 0.0 2.6 1 1 1 3 3 3 0 BT1 family OATP PF03137.15 EEQ28913.1 - 0.079 11.0 1.5 0.25 9.3 0.0 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4481 PF14800.1 EEQ28913.1 - 0.21 10.4 0.0 0.38 9.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) MFS_3 PF05977.8 EEQ28913.1 - 3.8 5.4 25.1 45 1.9 17.4 2.2 1 1 0 1 1 1 0 Transmembrane secretion effector Trypsin_2 PF13365.1 EEQ28914.1 - 0.0047 16.9 0.0 0.02 14.8 0.0 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S3 PF00944.14 EEQ28914.1 - 0.02 14.3 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Alphavirus core protein MFS_1 PF07690.11 EEQ28915.1 - 3.7e-41 141.0 50.2 2.8e-29 101.9 17.5 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ28915.1 - 4.9e-12 44.8 17.1 6.9e-12 44.3 11.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EEQ28915.1 - 0.0031 15.6 3.5 0.0031 15.6 2.4 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector Cellulase-like PF12876.2 EEQ28916.1 - 0.011 16.1 0.1 4.5 7.8 0.0 3.1 4 0 0 4 4 4 0 Sugar-binding cellulase-like FtsJ PF01728.14 EEQ28917.1 - 3.3e-14 53.2 0.0 4.8e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EEQ28917.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.13 EEQ28918.1 - 4.3e-08 32.9 10.2 1.2e-07 31.5 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EEQ28919.1 - 2.7e-11 43.6 0.1 9.1e-11 41.9 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEQ28919.1 - 0.00044 19.9 0.2 0.0021 17.7 0.1 1.9 1 1 0 1 1 1 1 KR domain DFP PF04127.10 EEQ28919.1 - 0.00073 19.2 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 EEQ28919.1 - 0.0024 17.6 0.1 0.005 16.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EEQ28919.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 EEQ28920.1 - 1.2e-39 136.1 0.0 1.2e-27 96.5 0.0 2.1 1 1 0 2 2 2 2 Cytochrome P450 DUF924 PF06041.6 EEQ28920.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF924) p450 PF00067.17 EEQ28921.1 - 6.3e-31 107.3 0.1 7.8e-31 107.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EEQ28922.1 - 8.8e-70 235.1 0.0 1.4e-40 138.9 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEQ28922.1 - 6.3e-34 117.1 0.0 9.5e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EEQ28922.1 - 2e-07 31.1 0.0 5.1e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 2OG-FeII_Oxy PF03171.15 EEQ28923.1 - 2.4e-14 53.4 0.0 1.5e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EEQ28923.1 - 2.3e-09 37.8 0.0 3.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ABC_membrane PF00664.18 EEQ28924.1 - 6.1e-81 271.8 34.0 2.6e-43 148.4 5.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ28924.1 - 2.3e-68 228.7 0.2 4.9e-34 117.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EEQ28924.1 - 6.5e-12 46.0 0.6 0.021 14.7 0.0 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EEQ28924.1 - 1.1e-11 44.3 2.8 0.0022 17.2 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEQ28924.1 - 1.1e-07 32.0 2.0 0.0042 17.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EEQ28924.1 - 4.2e-07 30.8 0.0 0.071 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ28924.1 - 2.2e-06 27.0 1.1 0.031 13.8 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EEQ28924.1 - 4.6e-06 26.8 1.4 0.1 12.7 0.0 3.6 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 EEQ28924.1 - 1.1e-05 24.6 0.0 0.19 10.8 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EEQ28924.1 - 3.4e-05 24.1 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ28924.1 - 3.7e-05 23.2 0.1 0.28 10.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 EEQ28924.1 - 8e-05 22.3 0.3 5.7 6.4 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.1 EEQ28924.1 - 0.00012 22.0 0.0 2.2 8.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EEQ28924.1 - 0.00018 20.2 3.5 0.0029 16.2 0.1 3.0 3 0 0 3 3 3 1 Predicted ATPase of the ABC class PRK PF00485.13 EEQ28924.1 - 0.00019 21.0 0.0 0.17 11.4 0.0 2.6 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.1 EEQ28924.1 - 0.00076 19.3 2.7 0.94 9.4 0.2 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EEQ28924.1 - 0.00086 19.0 0.1 2.4 7.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EEQ28924.1 - 0.00099 19.4 1.9 0.088 13.1 0.0 3.1 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.12 EEQ28924.1 - 0.0016 18.3 0.0 0.34 10.6 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_28 PF13521.1 EEQ28924.1 - 0.0037 17.2 0.1 2.8 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EEQ28924.1 - 0.0037 16.3 0.3 3.9 6.4 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 EEQ28924.1 - 0.0055 16.8 2.2 5.6 7.1 0.0 4.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 EEQ28924.1 - 0.011 15.2 4.1 1.1 8.6 0.1 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.16 EEQ28924.1 - 0.016 14.3 0.0 1.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EEQ28924.1 - 0.02 14.7 0.0 8.7 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEQ28924.1 - 0.022 13.5 1.2 4 6.2 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EEQ28924.1 - 0.024 14.7 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EEQ28924.1 - 0.036 13.1 0.1 1.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.15 EEQ28924.1 - 0.04 13.5 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 EEQ28924.1 - 0.047 13.6 0.0 4.2 7.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EEQ28924.1 - 0.059 12.7 3.5 12 5.2 0.1 4.3 4 1 0 4 4 4 0 AAA-like domain G-alpha PF00503.15 EEQ28924.1 - 0.14 10.8 0.1 4.7 5.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.10 EEQ28924.1 - 0.23 10.1 0.2 2.3 6.8 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Cys_Met_Meta_PP PF01053.15 EEQ28925.1 - 3.4e-109 364.6 0.0 2.7e-106 355.1 0.0 2.1 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEQ28925.1 - 1.5e-10 40.6 0.0 2.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ28925.1 - 4e-08 32.4 0.1 6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ28925.1 - 4.5e-07 29.2 0.0 7.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EEQ28925.1 - 0.0037 16.4 0.0 0.016 14.3 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase ABC_membrane PF00664.18 EEQ28926.1 - 1.5e-90 303.3 37.7 1.8e-46 158.7 8.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ28926.1 - 8.7e-69 230.1 0.0 2e-33 115.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ28926.1 - 1.2e-14 54.0 0.1 0.00021 20.5 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ28926.1 - 6e-12 46.1 0.0 0.00095 19.2 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EEQ28926.1 - 2.3e-08 33.4 1.5 0.0004 19.8 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ28926.1 - 3.2e-08 33.7 1.8 0.00059 19.8 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EEQ28926.1 - 6.6e-08 31.5 3.0 0.005 15.4 0.1 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EEQ28926.1 - 7.5e-08 33.2 0.0 0.023 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEQ28926.1 - 9.2e-07 28.1 0.1 0.016 14.3 0.0 2.7 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEQ28926.1 - 2.5e-06 27.6 0.8 0.082 13.0 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ28926.1 - 3.8e-06 26.4 2.3 0.057 12.8 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 EEQ28926.1 - 3e-05 24.2 3.6 0.18 12.0 0.2 4.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EEQ28926.1 - 3.2e-05 23.6 0.9 1.4 8.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.9 EEQ28926.1 - 0.00015 21.5 0.2 0.34 10.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EEQ28926.1 - 0.00017 21.4 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEQ28926.1 - 0.00062 20.0 0.5 1.2 9.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EEQ28926.1 - 0.0014 18.1 3.2 2.5 7.4 0.2 4.3 4 0 0 4 4 4 1 AAA-like domain SbcCD_C PF13558.1 EEQ28926.1 - 0.0016 18.3 3.1 1.7 8.6 0.3 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EEQ28926.1 - 0.003 17.4 0.1 1.6 8.6 0.0 3.7 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 EEQ28926.1 - 0.0049 16.5 0.2 5 6.8 0.0 3.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 EEQ28926.1 - 0.0055 15.4 0.1 0.25 10.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 EEQ28926.1 - 0.0056 15.7 0.1 1.8 7.6 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 EEQ28926.1 - 0.0063 16.2 0.9 3.3 7.5 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_23 PF13476.1 EEQ28926.1 - 0.0072 16.6 2.2 2.3 8.4 0.0 3.4 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EEQ28926.1 - 0.013 15.6 0.0 3.4 7.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.17 EEQ28926.1 - 0.014 14.8 0.2 6.6 6.1 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 EEQ28926.1 - 0.015 15.1 0.3 0.61 9.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_28 PF13521.1 EEQ28926.1 - 0.019 14.9 0.4 5.7 6.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EEQ28926.1 - 0.073 12.7 0.1 1.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Katanin_con80 PF13925.1 EEQ28926.1 - 0.14 11.9 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 con80 domain of Katanin Ribosomal_L39 PF00832.15 EEQ28928.1 - 5.5e-22 76.9 9.0 8.2e-22 76.3 6.3 1.3 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.14 EEQ28929.1 - 1.2e-39 134.1 2.0 1.9e-39 133.5 1.4 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EEQ28929.1 - 3.6e-24 84.6 0.1 7.7e-24 83.5 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Glyco_transf_22 PF03901.12 EEQ28930.1 - 3.8e-59 200.7 24.2 5.5e-59 200.2 16.8 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XPC-binding PF09280.6 EEQ28931.1 - 2.8e-23 81.1 15.6 5.2e-23 80.2 10.8 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EEQ28931.1 - 9.1e-21 73.0 0.1 1.6e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEQ28931.1 - 9.2e-18 63.5 1.3 1.4e-08 34.3 0.1 3.1 3 0 0 3 3 3 2 UBA/TS-N domain Rad60-SLD PF11976.3 EEQ28931.1 - 3.5e-08 33.0 0.1 6.5e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EEQ28931.1 - 0.0009 18.7 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain MCM_N PF14551.1 EEQ28931.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 MCM N-terminal domain Rap1_C PF11626.3 EEQ28931.1 - 0.024 14.5 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rad60-SLD_2 PF13881.1 EEQ28931.1 - 0.046 13.6 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Serglycin PF04360.7 EEQ28931.1 - 0.21 11.3 3.1 0.68 9.6 2.1 1.9 1 0 0 1 1 1 0 Serglycin DUF3431 PF11913.3 EEQ28932.1 - 2.8e-74 249.3 1.2 3.5e-74 249.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) Aminotran_1_2 PF00155.16 EEQ28933.1 - 5.8e-35 120.9 0.0 3.2e-21 75.7 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ28933.1 - 1.5e-05 23.9 0.0 0.0024 16.7 0.0 2.5 3 0 0 3 3 3 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EEQ28933.1 - 2.5e-05 22.7 0.0 0.0011 17.3 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EEQ28933.1 - 0.0033 16.5 0.0 0.0084 15.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEQ28933.1 - 0.019 14.0 0.0 0.058 12.4 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family EnY2 PF10163.4 EEQ28933.1 - 0.097 12.6 0.1 9.7 6.1 0.0 2.8 3 0 0 3 3 3 0 Transcription factor e(y)2 PHO4 PF01384.15 EEQ28934.1 - 4.6e-121 403.4 17.0 5.3e-121 403.2 11.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family Pkinase PF00069.20 EEQ28936.1 - 1.2e-29 103.2 0.0 2e-29 102.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ28936.1 - 6.1e-15 54.9 0.0 1.8e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EEQ28936.1 - 0.048 13.3 0.1 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ28936.1 - 0.08 12.2 0.3 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 RIO1 family adh_short PF00106.20 EEQ28937.1 - 1.8e-23 83.2 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ28937.1 - 9.4e-15 55.0 0.0 1.2e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ28937.1 - 3.1e-07 30.2 0.0 6.6e-07 29.1 0.0 1.5 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 EEQ28937.1 - 2.5e-06 26.8 0.0 3.2e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EEQ28937.1 - 0.00068 19.6 0.0 0.004 17.1 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding DASH_Duo1 PF08651.5 EEQ28937.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 PQ-loop PF04193.9 EEQ28938.1 - 4.6e-40 134.9 10.6 2.6e-20 71.6 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF566 PF04484.7 EEQ28938.1 - 0.15 11.5 4.3 0.23 10.9 3.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) SGS PF05002.10 EEQ28939.1 - 9.8e-26 89.3 3.5 3.2e-25 87.6 2.4 2.0 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EEQ28939.1 - 1.2e-19 70.6 0.0 3.2e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EEQ28939.1 - 6.9e-09 35.2 0.5 6.9e-09 35.2 0.4 1.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EEQ28939.1 - 0.00086 19.0 1.4 0.095 12.6 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ28939.1 - 0.0023 17.4 0.3 0.0023 17.4 0.2 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ28939.1 - 0.011 16.3 3.4 0.018 15.6 0.4 2.3 1 1 2 3 3 3 0 Tetratricopeptide repeat Prenyltrans PF00432.16 EEQ28940.1 - 9.5e-32 108.2 4.1 5.2e-10 38.7 0.0 5.3 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EEQ28940.1 - 5e-29 100.4 0.0 4.2e-12 46.0 0.0 6.0 5 1 1 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 EEQ28940.1 - 1.3e-26 93.1 0.3 2.8e-15 56.6 0.1 4.5 4 2 0 4 4 4 3 Prenyltransferase-like Pec_lyase PF09492.5 EEQ28940.1 - 3.6e-08 32.9 3.7 0.098 11.8 0.0 4.8 4 1 2 6 6 6 4 Pectic acid lyase A2M_comp PF07678.9 EEQ28940.1 - 0.043 13.0 0.0 0.61 9.2 0.0 2.6 2 1 1 3 3 3 0 A-macroglobulin complement component Ank_2 PF12796.2 EEQ28942.1 - 1.1e-39 134.6 3.4 6.6e-16 58.4 0.1 3.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEQ28942.1 - 2.8e-25 85.8 3.9 7.5e-07 28.7 0.0 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.25 EEQ28942.1 - 5.1e-25 85.9 3.6 1.7e-09 37.0 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EEQ28942.1 - 2.3e-21 75.7 0.8 2.2e-07 31.1 0.0 5.0 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ28942.1 - 3.8e-17 61.9 0.5 2.2e-08 34.1 0.0 5.7 5 2 2 7 7 7 4 Ankyrin repeats (many copies) DUF421 PF04239.7 EEQ28942.1 - 0.081 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF421) eIF-6 PF01912.13 EEQ28943.1 - 5.3e-82 273.7 0.9 8e-82 273.1 0.6 1.3 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 EEQ28943.1 - 0.13 11.9 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 Phage holin family 6 SRR1 PF07985.7 EEQ28944.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 SRR1 TPR_11 PF13414.1 EEQ28945.1 - 7.3e-12 44.7 0.0 3.2e-10 39.4 0.0 2.7 2 0 0 2 2 2 1 TPR repeat UBA PF00627.26 EEQ28945.1 - 2.4e-07 30.3 0.0 8.8e-07 28.5 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 EEQ28945.1 - 2.8e-07 29.9 0.0 0.069 13.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ28945.1 - 0.00082 18.8 0.0 3.3 7.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ28945.1 - 0.0023 18.5 0.0 0.78 10.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ28945.1 - 0.011 15.6 0.9 0.33 10.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.2 EEQ28946.1 - 1.3e-28 99.1 6.1 3e-16 59.5 0.7 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ28946.1 - 1.2e-18 66.6 2.3 2.4e-08 33.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EEQ28946.1 - 1.2e-16 59.6 2.3 8.2e-07 28.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EEQ28946.1 - 2.4e-14 53.3 0.1 4.1e-07 30.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ28946.1 - 3.1e-11 42.3 0.4 0.0083 16.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 EEQ28946.1 - 0.015 15.2 6.4 0.032 14.1 4.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor RILP PF11461.3 EEQ28946.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein AMP-binding PF00501.23 EEQ28947.1 - 2.4e-82 276.5 0.0 3.2e-82 276.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EEQ28947.1 - 7.1e-19 67.7 0.0 1.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EEQ28947.1 - 1.1e-10 41.5 0.0 8.9e-10 38.6 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site DegT_DnrJ_EryC1 PF01041.12 EEQ28948.1 - 2.5e-57 194.5 0.0 5.5e-57 193.4 0.0 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.17 EEQ28948.1 - 7.2e-20 71.7 0.0 1.9e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEQ28948.1 - 0.00063 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EEQ28948.1 - 0.002 18.3 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Peroxin-22 PF12827.2 EEQ28948.1 - 0.11 12.2 0.1 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family 5_nucleotid_C PF02872.13 EEQ28952.1 - 2.8e-35 121.5 0.0 4.9e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EEQ28952.1 - 0.0038 16.6 0.1 0.14 11.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase tRNA-synt_1e PF01406.14 EEQ28953.1 - 1.5e-113 378.9 0.0 2.4e-113 378.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EEQ28953.1 - 6.9e-05 21.6 4.2 0.074 11.6 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EEQ28953.1 - 0.0018 18.4 0.0 0.007 16.5 0.0 2.1 1 0 0 1 1 1 1 DALR domain GCD14 PF08704.5 EEQ28954.1 - 8.5e-64 215.3 0.0 7.3e-63 212.3 0.0 2.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EEQ28954.1 - 0.00035 20.5 0.0 0.00093 19.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ28954.1 - 0.0095 16.5 0.1 0.024 15.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ28954.1 - 0.027 14.0 0.0 0.07 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ABC_membrane PF00664.18 EEQ28955.1 - 8.4e-72 241.8 40.4 1.8e-38 132.5 10.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ28955.1 - 5.2e-70 234.0 0.0 1.5e-34 119.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ28955.1 - 3.3e-15 55.9 0.1 8.1e-05 21.9 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ28955.1 - 5.6e-10 39.6 0.4 0.11 12.4 0.0 4.3 2 2 0 4 4 4 2 AAA domain ABC_ATPase PF09818.4 EEQ28955.1 - 3.1e-09 35.9 0.2 0.0029 16.2 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EEQ28955.1 - 1.4e-08 34.9 0.4 0.008 16.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEQ28955.1 - 2.2e-08 33.5 2.7 0.0028 17.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ28955.1 - 7.4e-07 30.0 0.0 0.074 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain DEAD PF00270.24 EEQ28955.1 - 2.2e-06 27.2 0.1 0.0031 17.0 0.0 3.0 3 1 0 3 3 2 2 DEAD/DEAH box helicase SbcCD_C PF13558.1 EEQ28955.1 - 4.2e-06 26.5 1.5 0.041 13.8 0.1 3.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EEQ28955.1 - 5.4e-06 25.6 0.0 0.013 14.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEQ28955.1 - 1.8e-05 25.2 1.2 0.19 12.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EEQ28955.1 - 3.5e-05 23.3 2.5 2.1 7.7 0.0 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 EEQ28955.1 - 6.4e-05 23.1 0.3 0.36 10.9 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EEQ28955.1 - 0.00013 21.4 0.1 1.8 7.9 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 EEQ28955.1 - 0.00037 20.6 0.1 1.9 8.6 0.0 4.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EEQ28955.1 - 0.00061 19.3 0.1 0.23 10.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EEQ28955.1 - 0.00064 19.6 0.4 1.8 8.5 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EEQ28955.1 - 0.0012 19.1 0.0 1.3 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EEQ28955.1 - 0.0016 18.3 0.6 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 MobB PF03205.9 EEQ28955.1 - 0.0025 17.5 0.1 1.3 8.7 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEQ28955.1 - 0.0028 17.5 0.0 2 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEQ28955.1 - 0.016 14.3 0.0 2.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 EEQ28955.1 - 0.016 14.9 0.1 20 4.8 0.0 4.0 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EEQ28955.1 - 0.055 12.8 2.4 25 4.2 0.0 4.2 5 0 0 5 5 5 0 IstB-like ATP binding protein ResIII PF04851.10 EEQ28955.1 - 0.062 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Dynamin_N PF00350.18 EEQ28955.1 - 0.11 12.3 2.4 16 5.2 0.1 3.6 4 0 0 4 4 4 0 Dynamin family ATP-synt_ab PF00006.20 EEQ28955.1 - 0.41 10.1 5.1 4.5 6.7 2.9 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 EEQ28955.1 - 0.48 9.4 0.0 13 4.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF1688 PF07958.6 EEQ28956.1 - 1.6e-161 537.5 0.0 1.9e-161 537.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) LRR_4 PF12799.2 EEQ28957.1 - 0.2 11.3 2.7 6.6 6.4 0.7 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) TrkH PF02386.11 EEQ28959.1 - 1.2e-117 392.5 9.8 4.1e-115 384.1 4.0 2.1 2 0 0 2 2 2 2 Cation transport protein COesterase PF00135.23 EEQ28962.1 - 1.4e-101 340.8 1.0 1.2e-92 311.3 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ28962.1 - 9.9e-13 48.1 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ28962.1 - 0.00045 20.0 0.0 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEQ28962.1 - 0.0076 15.7 0.0 0.025 14.0 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF2424 PF10340.4 EEQ28962.1 - 0.016 13.9 0.1 0.053 12.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Dynamin_M PF01031.15 EEQ28963.1 - 1.2e-104 349.3 0.0 2.3e-104 348.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EEQ28963.1 - 7.8e-46 155.9 0.5 1.9e-45 154.6 0.3 1.7 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 EEQ28963.1 - 9.7e-28 95.9 2.7 2.6e-27 94.5 1.8 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEQ28963.1 - 0.00027 20.8 0.8 0.0027 17.6 0.6 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EEQ28964.1 - 5.2e-114 379.0 0.0 9.2e-114 378.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEQ28964.1 - 1.2e-18 67.5 1.3 2.7e-18 66.4 0.7 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEQ28964.1 - 6.8e-15 55.0 2.5 1.6e-14 53.8 1.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HSBP1 PF06825.7 EEQ28964.1 - 0.078 12.5 0.1 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 WD40 PF00400.27 EEQ28965.1 - 3.8e-37 124.8 6.5 4e-07 29.6 0.0 7.0 7 1 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EEQ28965.1 - 0.00029 20.6 0.2 0.028 14.1 0.1 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EEQ28965.1 - 0.0012 18.4 0.0 15 5.3 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat CLTH PF10607.4 EEQ28965.1 - 0.0022 17.6 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DEAD PF00270.24 EEQ28966.1 - 5.4e-40 136.6 0.3 1.2e-39 135.4 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ28966.1 - 2.6e-29 100.8 0.2 5.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EEQ28966.1 - 0.0013 18.4 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ28966.1 - 0.011 15.3 0.3 0.027 14.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EEQ28966.1 - 0.024 14.4 0.1 0.051 13.4 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EEQ28966.1 - 0.031 14.0 0.3 0.12 12.1 0.1 2.2 1 1 1 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 EEQ28966.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.20 EEQ28966.1 - 0.1 11.7 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_11 PF13086.1 EEQ28966.1 - 0.1 12.1 0.2 0.14 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEQ28966.1 - 0.17 11.9 0.9 0.89 9.7 0.7 2.1 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 EEQ28967.1 - 1e-68 230.7 1.1 2.4e-68 229.5 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EEQ28967.1 - 5.6e-10 38.5 0.1 1.1e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EEQ28967.1 - 8.5e-10 38.5 1.2 5.4e-08 32.7 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ28967.1 - 2.8e-08 33.6 0.3 2.8e-08 33.6 0.2 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEQ28967.1 - 0.00072 19.6 0.1 0.018 15.1 0.0 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EEQ28967.1 - 0.004 17.3 3.5 0.11 12.9 0.2 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ28967.1 - 0.081 13.3 4.5 0.39 11.1 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF951 PF06107.6 EEQ28967.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-DBF PF07535.7 EEQ28967.1 - 0.62 9.7 3.2 1.1 9.0 0.1 3.0 3 0 0 3 3 3 0 DBF zinc finger DNA_ligase_A_M PF01068.16 EEQ28969.1 - 1.4e-19 70.2 0.0 2.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEQ28969.1 - 1.1e-13 51.4 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus APC8 PF04049.8 EEQ28970.1 - 6.2e-51 171.8 0.2 3.3e-50 169.5 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EEQ28970.1 - 6.4e-25 85.6 5.9 0.00014 21.2 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ28970.1 - 6e-22 77.0 13.4 3.3e-07 29.8 0.1 6.4 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 EEQ28970.1 - 4.8e-20 69.7 18.7 0.052 13.4 0.0 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ28970.1 - 9.9e-19 67.5 17.0 4.9e-05 23.8 0.0 6.9 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ28970.1 - 1.2e-15 55.9 9.8 0.00029 20.3 0.0 7.8 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ28970.1 - 5.6e-13 48.2 11.5 0.0053 17.2 0.0 8.3 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ28970.1 - 3e-11 43.0 17.7 0.0009 19.1 0.2 7.2 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ28970.1 - 3.9e-11 43.1 7.1 0.045 14.0 0.2 6.7 6 1 0 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EEQ28970.1 - 2.3e-09 37.2 14.7 0.25 11.4 0.1 5.9 5 1 2 7 7 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EEQ28970.1 - 3.3e-08 33.0 3.2 0.92 9.8 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ28970.1 - 9.2e-08 31.8 12.1 0.00017 21.3 0.3 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ28970.1 - 2.5e-06 27.5 19.6 7.3 7.2 0.1 9.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ28970.1 - 1e-05 24.9 8.4 0.72 9.7 0.0 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ28970.1 - 0.00031 19.8 9.9 0.00055 19.0 2.2 3.7 1 1 1 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.4 EEQ28970.1 - 0.012 14.1 0.1 0.026 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) polyprenyl_synt PF00348.12 EEQ28971.1 - 2.4e-69 233.1 0.0 2.8e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase LIX1 PF14954.1 EEQ28971.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 2 0 0 2 2 2 0 Limb expression 1 Glycogen_syn PF05693.8 EEQ28972.1 - 8.3e-300 995.6 0.0 1.4e-299 994.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EEQ28972.1 - 3.3e-06 26.6 0.0 0.0041 16.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEQ28972.1 - 4.3e-06 26.9 0.2 9.2e-06 25.8 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EEQ28972.1 - 4.9e-05 22.9 0.0 9.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain NPCC PF08058.6 EEQ28973.1 - 3.7e-31 107.9 0.1 2.9e-30 105.0 0.1 1.9 1 1 0 1 1 1 1 Nuclear pore complex component AMP-binding PF00501.23 EEQ28974.1 - 5.8e-14 51.3 0.0 5.4e-13 48.1 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Xpo1 PF08389.7 EEQ28975.1 - 0.22 11.4 1.2 6.7 6.6 0.5 2.2 2 0 0 2 2 2 0 Exportin 1-like protein Ribosomal_L19 PF01245.15 EEQ28976.1 - 5.5e-16 58.3 0.0 1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Methyltransf_24 PF13578.1 EEQ28977.1 - 8.2e-15 55.5 0.0 1.3e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EEQ28977.1 - 9.9e-07 28.0 0.0 5.6e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEQ28977.1 - 0.0017 18.9 0.0 0.0046 17.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF365 PF04033.7 EEQ28977.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Hap4_Hap_bind PF10297.4 EEQ28978.1 - 1.6e-08 34.1 8.1 3.4e-08 33.0 5.6 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EEQ28978.1 - 8.9e-07 28.7 16.5 2.3e-06 27.4 10.3 2.2 1 1 1 2 2 2 1 bZIP transcription factor Phage_int_SAM_5 PF13102.1 EEQ28978.1 - 0.0041 17.1 1.7 0.0074 16.2 1.2 1.3 1 0 0 1 1 1 1 Phage integrase SAM-like domain Fmp27_WPPW PF10359.4 EEQ28978.1 - 0.15 10.4 6.9 0.2 10.0 4.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain bZIP_2 PF07716.10 EEQ28978.1 - 0.16 11.8 18.1 3.9 7.3 12.5 2.4 1 1 0 1 1 1 0 Basic region leucine zipper V_ATPase_I PF01496.14 EEQ28978.1 - 0.69 7.6 2.7 0.93 7.2 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cauli_AT PF03233.8 EEQ28978.1 - 1.2 8.8 5.7 8.6 6.0 3.8 2.1 1 1 1 2 2 2 0 Aphid transmission protein IncA PF04156.9 EEQ28978.1 - 8.3 5.9 9.3 15 5.1 6.4 1.4 1 0 0 1 1 1 0 IncA protein Mito_carr PF00153.22 EEQ28979.1 - 1.1e-09 37.8 0.4 0.98 9.1 0.0 5.5 4 1 0 4 4 4 4 Mitochondrial carrier protein Fer2 PF00111.22 EEQ28980.1 - 7.3e-14 51.2 0.6 1.1e-13 50.7 0.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.7 EEQ28981.1 - 1.3e-36 125.4 7.4 1.3e-36 125.4 5.1 2.1 2 1 0 2 2 2 1 Rrp15p Astro_capsid PF03115.9 EEQ28981.1 - 1.1 7.4 12.3 1.5 7.0 8.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SRP54 PF00448.17 EEQ28982.1 - 1.5e-74 249.7 2.2 2.8e-74 248.8 1.5 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EEQ28982.1 - 1.7e-23 82.8 0.2 1.7e-23 82.8 0.1 4.7 2 1 4 6 6 4 1 Signal peptide binding domain SRP54_N PF02881.14 EEQ28982.1 - 4.5e-16 58.7 0.2 9.9e-16 57.6 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EEQ28982.1 - 1.9e-08 33.9 0.2 5.5e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EEQ28982.1 - 2.6e-07 30.6 0.0 6.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ28982.1 - 4.1e-05 22.7 0.1 7.9e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EEQ28982.1 - 6.8e-05 23.6 0.0 0.0002 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EEQ28982.1 - 0.00017 21.3 0.2 0.00055 19.6 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EEQ28982.1 - 0.00051 19.6 0.8 0.021 14.3 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EEQ28982.1 - 0.00054 19.4 0.5 0.0021 17.4 0.3 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEQ28982.1 - 0.00075 19.4 0.1 1.5 8.7 0.0 2.6 1 1 1 2 2 2 2 AAA domain 6PF2K PF01591.13 EEQ28982.1 - 0.0015 17.6 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase APS_kinase PF01583.15 EEQ28982.1 - 0.0017 18.0 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ArgK PF03308.11 EEQ28982.1 - 0.0042 15.9 0.0 0.0042 15.9 0.0 2.7 3 1 1 4 4 4 1 ArgK protein AAA_16 PF13191.1 EEQ28982.1 - 0.0055 16.7 0.1 0.018 15.0 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain Thymidylate_kin PF02223.12 EEQ28982.1 - 0.0062 15.9 0.2 0.022 14.1 0.1 1.9 1 0 0 1 1 1 1 Thymidylate kinase SRPRB PF09439.5 EEQ28982.1 - 0.0079 15.4 1.8 1.4 8.1 0.1 3.2 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EEQ28982.1 - 0.01 15.9 0.0 0.033 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ28982.1 - 0.031 14.5 0.1 0.085 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 EEQ28982.1 - 0.036 13.2 0.0 0.092 11.9 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family VirE PF05272.6 EEQ28982.1 - 0.038 13.4 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E TrwB_AAD_bind PF10412.4 EEQ28982.1 - 0.05 12.2 0.1 0.16 10.5 0.0 1.8 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 EEQ28982.1 - 0.062 13.6 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.1 EEQ28982.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EEQ28982.1 - 0.36 9.7 2.1 0.21 10.5 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoD PF09423.5 EEQ28983.1 - 2.5e-58 197.7 0.0 3.8e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_18 PF00704.23 EEQ28984.1 - 1.6e-09 37.6 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF496 PF04363.7 EEQ28984.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF496) adh_short_C2 PF13561.1 EEQ28988.1 - 8.4e-30 104.2 0.0 9.9e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ28988.1 - 1.3e-26 93.4 1.2 1.8e-26 93.0 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ28988.1 - 7.6e-13 48.5 1.0 1e-12 48.1 0.7 1.1 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EEQ28988.1 - 0.028 13.1 0.1 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FNIP_C PF14638.1 EEQ28988.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus YtkA PF13115.1 EEQ28989.1 - 0.77 10.1 4.7 0.54 10.6 0.1 3.1 3 0 0 3 3 3 0 YtkA-like CoA_transf_3 PF02515.12 EEQ28990.1 - 5e-45 153.0 0.0 7.2e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III BAF1_ABF1 PF04684.8 EEQ28991.1 - 0.0018 17.2 18.9 0.0031 16.4 13.1 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Methyltransf_23 PF13489.1 EEQ28992.1 - 6.1e-13 48.7 0.0 1.6e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ28992.1 - 0.00012 21.6 0.0 0.03 13.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ28992.1 - 0.0041 17.5 0.0 0.0086 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ28992.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ28992.1 - 0.074 13.6 0.1 17 6.0 0.0 3.0 1 1 1 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ28992.1 - 0.076 13.3 0.1 1 9.7 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain CAF1A PF12253.3 EEQ28994.1 - 3.9e-25 87.7 4.9 3.9e-25 87.7 3.4 3.6 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EEQ28994.1 - 1.9e-15 56.8 58.4 1.9e-15 56.8 40.5 2.3 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Daxx PF03344.10 EEQ28994.1 - 0.014 13.9 31.7 0.0036 15.8 16.3 2.2 2 0 0 2 2 2 0 Daxx Family Mem_trans PF03547.13 EEQ28994.1 - 0.5 8.6 3.9 0.77 7.9 2.7 1.3 1 0 0 1 1 1 0 Membrane transport protein SAPS PF04499.10 EEQ28994.1 - 1.9 7.0 18.0 0.092 11.3 8.8 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 EEQ28994.1 - 2 6.2 40.6 1.5 6.6 1.1 2.1 2 0 0 2 2 2 0 Nop14-like family Raftlin PF15250.1 EEQ28994.1 - 4.2 5.8 21.7 8.1 4.8 15.1 1.4 1 0 0 1 1 1 0 Raftlin CDC27 PF09507.5 EEQ28994.1 - 5.4 6.1 53.1 0.18 11.0 29.5 2.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 IPP-2 PF04979.9 EEQ28998.1 - 1.9e-08 34.6 18.9 2.7e-06 27.6 0.9 2.9 1 1 2 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) Carb_anhydrase PF00194.16 EEQ28998.1 - 0.03 13.2 0.1 0.041 12.8 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase CRAL_TRIO PF00650.15 EEQ28999.1 - 3.8e-13 49.2 0.0 5.7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEQ28999.1 - 0.00035 20.6 0.2 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF1546 PF07571.8 EEQ29000.1 - 1.8e-32 111.2 0.0 4.9e-32 109.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EEQ29000.1 - 3.2e-25 87.8 0.2 1.2e-24 85.9 0.0 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EEQ29000.1 - 0.00028 20.9 0.0 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EEQ29000.1 - 0.0088 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated TAF4 PF05236.9 EEQ29000.1 - 0.034 13.4 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CBFD_NFYB_HMF PF00808.18 EEQ29000.1 - 0.079 13.0 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAM_decarbox PF01536.11 EEQ29002.1 - 3.6e-87 292.1 0.0 1.5e-86 290.1 0.0 1.9 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1024 PF06260.7 EEQ29002.1 - 0.22 11.6 0.9 0.45 10.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) TAFII28 PF04719.9 EEQ29003.1 - 4.9e-21 74.3 0.1 2.1e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Ribosomal_60s PF00428.14 EEQ29003.1 - 0.0065 16.8 1.6 0.0065 16.8 1.1 3.0 2 1 0 2 2 2 1 60s Acidic ribosomal protein Daxx PF03344.10 EEQ29003.1 - 0.34 9.3 6.3 0.51 8.7 4.4 1.3 1 1 0 1 1 1 0 Daxx Family 60KD_IMP PF02096.15 EEQ29004.1 - 1.8e-29 102.8 0.0 3.7e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.6 EEQ29005.1 - 1.9e-29 101.2 0.0 2.3e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 EEQ29006.1 - 4.8e-25 87.6 0.1 8.5e-25 86.8 0.1 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EEQ29006.1 - 5.7e-15 55.1 0.0 9.2e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EEQ29006.1 - 2.6e-14 52.4 0.0 4.2e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain ParA PF10609.4 EEQ29007.1 - 3.2e-35 119.8 0.1 6.3e-35 118.9 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEQ29007.1 - 9.4e-15 54.5 0.0 2.5e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EEQ29007.1 - 1.1e-06 27.8 0.0 2.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EEQ29007.1 - 9.7e-06 24.8 0.4 0.00015 20.9 0.5 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EEQ29007.1 - 1.4e-05 25.0 0.1 5.7e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEQ29007.1 - 0.00062 19.2 0.2 0.0012 18.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain YhjQ PF06564.7 EEQ29007.1 - 0.0053 16.1 0.3 0.015 14.6 0.2 1.7 2 0 0 2 2 2 1 YhjQ protein ArgK PF03308.11 EEQ29007.1 - 0.012 14.4 0.1 0.012 14.4 0.1 1.5 2 0 0 2 2 2 0 ArgK protein AAA_26 PF13500.1 EEQ29007.1 - 0.018 14.6 0.6 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EEQ29007.1 - 0.023 14.3 0.1 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_10 PF12846.2 EEQ29007.1 - 0.054 12.9 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain OrfB_Zn_ribbon PF07282.6 EEQ29007.1 - 0.059 13.0 0.5 0.13 11.9 0.1 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF258 PF03193.11 EEQ29007.1 - 0.09 11.9 1.1 0.16 11.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Desulfoferrod_N PF06397.7 EEQ29007.1 - 0.91 8.9 5.3 0.13 11.6 0.6 1.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain COG2 PF06148.6 EEQ29009.1 - 2.1e-32 111.7 1.9 4e-32 110.8 1.3 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EEQ29009.1 - 1.6e-06 27.8 1.7 2.6e-06 27.1 0.1 2.2 1 1 1 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 EEQ29009.1 - 0.0027 16.2 2.8 0.0039 15.6 2.0 1.2 1 0 0 1 1 1 1 Dor1-like family DUF2450 PF10475.4 EEQ29009.1 - 0.0058 15.5 0.9 0.0075 15.2 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG5 PF10392.4 EEQ29009.1 - 0.011 15.6 0.8 0.011 15.6 0.5 2.1 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 EEQ29009.1 - 0.017 14.7 2.6 0.069 12.7 1.8 2.0 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 EEQ29009.1 - 0.08 11.5 3.1 0.13 10.9 2.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Sigma70_ner PF04546.8 EEQ29009.1 - 0.1 12.2 3.3 0.064 12.8 0.7 1.8 1 1 0 1 1 1 0 Sigma-70, non-essential region ISG65-75 PF11727.3 EEQ29009.1 - 0.26 10.2 3.0 0.55 9.2 2.0 1.6 1 1 0 1 1 1 0 Invariant surface glycoprotein Nop25 PF09805.4 EEQ29009.1 - 1.3 9.0 7.4 0.13 12.3 2.1 1.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) KLRAQ PF10205.4 EEQ29009.1 - 3.6 7.6 7.2 0.75 9.8 1.2 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein TBPIP PF07106.8 EEQ29009.1 - 4.7 6.7 9.7 9 5.8 0.7 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prothymosin PF03247.9 EEQ29009.1 - 5 7.3 13.8 12 6.0 9.6 1.7 1 1 0 1 1 1 0 Prothymosin/parathymosin family Ribosomal_L1 PF00687.16 EEQ29010.1 - 1.3e-34 119.5 0.0 1.9e-34 118.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family APH PF01636.18 EEQ29011.1 - 0.039 13.6 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EEQ29012.1 - 5.7e-32 110.7 44.7 1.2e-31 109.7 31.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ29012.1 - 1.1e-09 37.0 19.3 2.1e-09 36.1 13.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_16 PF00722.16 EEQ29013.1 - 1.3e-05 24.5 0.5 2.9e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 FAD_binding_3 PF01494.14 EEQ29014.1 - 4.8e-61 206.7 0.0 3.6e-60 203.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEQ29014.1 - 2.2e-20 72.9 0.0 7.5e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EEQ29014.1 - 0.032 14.1 0.0 0.091 12.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NMT1 PF09084.6 EEQ29015.1 - 0.028 14.0 0.0 0.56 9.7 0.0 2.2 1 1 1 2 2 2 0 NMT1/THI5 like p450 PF00067.17 EEQ29016.1 - 1.5e-57 195.1 0.0 2e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PQ-loop PF04193.9 EEQ29018.1 - 6.3e-22 76.8 5.4 1.1e-14 53.6 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat Glyco_hydro_31 PF01055.21 EEQ29019.1 - 4.5e-146 487.1 7.7 5.8e-146 486.7 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEQ29019.1 - 3.3e-25 87.7 0.2 8.3e-25 86.4 0.1 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like NDK PF00334.14 EEQ29020.1 - 1.1e-55 187.1 0.0 1.3e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.4 EEQ29021.1 - 1.8e-25 88.7 0.0 3.1e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EEQ29021.1 - 0.0024 18.1 0.4 0.0032 17.7 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) MTHFR PF02219.12 EEQ29022.1 - 2.5e-101 338.5 0.0 3.7e-101 338.0 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MFS_1 PF07690.11 EEQ29023.1 - 1.5e-29 102.8 26.4 1.5e-29 102.8 18.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Oxidored_q5_N PF01059.12 EEQ29023.1 - 0.046 13.5 1.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus TGT PF01702.13 EEQ29024.1 - 4.9e-41 140.5 0.0 6.6e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.12 EEQ29025.1 - 4.7e-43 146.7 0.0 5.5e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EEQ29025.1 - 0.007 16.3 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEQ29025.1 - 0.013 14.7 0.0 0.032 13.4 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 EEQ29025.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EEQ29025.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein GIY-YIG PF01541.19 EEQ29026.1 - 1.8e-06 28.2 0.0 4.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EEQ29026.1 - 7e-05 22.7 5.6 0.00013 21.8 3.9 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.1 EEQ29026.1 - 0.079 12.6 8.4 0.68 9.7 4.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 EEQ29026.1 - 0.15 11.8 7.9 0.28 10.9 5.5 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 EEQ29026.1 - 2.2 8.3 8.9 5.2 7.1 6.2 1.7 1 0 0 1 1 1 0 RING-variant domain PLU-1 PF08429.6 EEQ29027.1 - 3.2e-96 322.1 19.8 7.1e-96 321.0 11.3 2.2 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 EEQ29027.1 - 1.8e-42 144.1 0.3 5.5e-42 142.6 0.2 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EEQ29027.1 - 3.4e-27 94.1 0.1 1.3e-26 92.2 0.0 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EEQ29027.1 - 1.1e-18 66.6 27.4 7.4e-10 38.3 4.6 3.6 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 EEQ29027.1 - 1.1e-18 66.3 2.4 2.4e-18 65.3 1.7 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EEQ29027.1 - 1.2e-12 47.7 8.9 3.3e-12 46.2 6.2 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger PHD_2 PF13831.1 EEQ29027.1 - 0.0047 16.2 1.4 0.0047 16.2 1.0 2.8 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.1 EEQ29027.1 - 0.0056 15.9 10.6 0.016 14.4 1.3 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EEQ29027.1 - 6.2 6.6 22.8 0.44 10.3 2.1 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4219 PF13961.1 EEQ29028.1 - 0.00018 20.8 0.3 0.00026 20.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) FAM53 PF15242.1 EEQ29028.1 - 0.036 13.6 0.6 0.045 13.3 0.4 1.1 1 0 0 1 1 1 0 Family of FAM53 DHHA2 PF02833.9 EEQ29029.1 - 6.6e-13 48.9 0.0 1.2e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EEQ29029.1 - 7.3e-06 25.6 0.0 4.1e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 DHH family Transglut_core PF01841.14 EEQ29030.1 - 2.5e-11 43.7 0.2 1.2e-10 41.5 0.1 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EEQ29030.1 - 1.8e-08 33.7 0.2 4.1e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ29030.1 - 4.3e-06 26.0 2.0 6.2e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEQ29030.1 - 2.9e-05 23.5 0.1 0.00014 21.3 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain Transglut_core2 PF13369.1 EEQ29030.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Transglutaminase-like superfamily MIP PF00230.15 EEQ29031.1 - 8e-48 162.8 14.0 1e-47 162.5 9.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein HDA2-3 PF11496.3 EEQ29032.1 - 2.5e-28 98.7 4.2 1.6e-15 56.7 0.0 2.9 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 Bcr-Abl_Oligo PF09036.5 EEQ29032.1 - 0.27 11.1 3.6 0.37 10.7 0.1 3.0 1 1 2 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Laminin_II PF06009.7 EEQ29032.1 - 0.77 9.5 18.6 0.064 13.0 5.6 2.9 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.2 EEQ29032.1 - 0.8 9.5 34.4 0.065 13.0 13.7 3.3 1 1 2 3 3 3 0 Tropomyosin like Spc7 PF08317.6 EEQ29032.1 - 0.95 8.0 22.4 3.1 6.3 11.5 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 EEQ29032.1 - 5.1 6.6 27.8 0.32 10.5 13.5 2.9 1 1 1 2 2 2 0 IncA protein FMO-like PF00743.14 EEQ29033.1 - 4.3e-40 137.4 0.0 4.4e-19 68.0 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEQ29033.1 - 3e-14 53.5 0.0 2e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ29033.1 - 1.5e-08 34.7 0.0 6.9e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ29033.1 - 1.7e-07 31.1 0.0 9.5e-07 28.7 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEQ29033.1 - 2.8e-07 30.4 0.1 8.9e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEQ29033.1 - 3.6e-07 29.4 0.0 3.5e-05 22.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EEQ29033.1 - 7e-05 22.0 0.0 0.0026 16.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EEQ29033.1 - 0.039 14.3 0.1 0.77 10.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ29033.1 - 0.05 12.0 0.0 0.11 10.9 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Semialdhyde_dh PF01118.19 EEQ29033.1 - 0.084 13.1 0.0 5.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ThiF PF00899.16 EEQ29033.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 ThiF family Amino_oxidase PF01593.19 EEQ29033.1 - 0.13 11.3 0.1 0.46 9.4 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DAO PF01266.19 EEQ29033.1 - 0.13 11.0 0.0 0.45 9.3 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Strep_67kDa_ant PF06100.6 EEQ29033.1 - 0.17 10.2 0.1 1.9 6.7 0.0 2.0 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family POT1 PF02765.12 EEQ29034.1 - 7.2e-14 51.9 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Aminotran_1_2 PF00155.16 EEQ29036.1 - 3e-26 92.2 0.0 3.7e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 EEQ29036.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III IF4E PF01652.13 EEQ29037.1 - 3.6e-52 176.2 0.1 5.9e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Zip PF02535.17 EEQ29037.1 - 0.089 11.7 0.1 0.079 11.9 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_C48 PF02902.14 EEQ29038.1 - 1.3e-27 96.8 0.5 1.4e-13 51.0 0.3 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain SPC22 PF04573.7 EEQ29039.1 - 1.4e-32 112.3 0.3 3.9e-24 84.8 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase subunit Pmp3 PF01679.12 EEQ29040.1 - 3.4e-18 65.0 9.5 4.9e-18 64.5 6.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BCDHK_Adom3 PF10436.4 EEQ29042.1 - 8.7e-45 152.1 0.1 1.7e-44 151.2 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EEQ29042.1 - 6.3e-11 41.9 0.0 8.5e-10 38.3 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EEQ29042.1 - 0.0053 16.5 0.0 0.85 9.4 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 EEQ29042.1 - 0.019 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.3 EEQ29043.1 - 3e-87 291.9 0.0 4.1e-85 284.9 0.0 2.5 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EEQ29043.1 - 4.3e-70 235.4 1.2 2.5e-68 229.7 0.7 2.6 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EEQ29043.1 - 5.7e-51 173.2 0.1 1.1e-50 172.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ29043.1 - 1.4e-30 106.7 0.0 2.7e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EEQ29043.1 - 1.1e-10 41.8 0.1 6.9e-09 35.9 0.0 3.1 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 EEQ29043.1 - 0.0071 16.0 0.3 2.8 7.6 0.0 3.9 5 0 0 5 5 5 1 Ubiquitin-2 like Rad60 SUMO-like EMP24_GP25L PF01105.19 EEQ29044.1 - 1.2e-45 155.5 0.1 1.4e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CTD_bind PF04818.8 EEQ29045.1 - 0.019 15.1 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. FRG2 PF15315.1 EEQ29045.1 - 0.42 10.5 16.7 0.86 9.5 11.6 1.5 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Toprim_Crpt PF13342.1 EEQ29047.1 - 0.044 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase Helicase_C_3 PF13625.1 EEQ29048.1 - 1.7e-26 92.4 0.0 2.1e-25 88.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ29048.1 - 5.5e-14 52.4 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ29048.1 - 7.8e-13 48.0 0.0 1.8e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ29048.1 - 3.2e-11 42.5 0.3 5.2e-11 41.8 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_34 PF13872.1 EEQ29048.1 - 0.0064 15.3 0.1 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 SH3BGR PF04908.10 EEQ29048.1 - 0.047 13.6 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Dynamin_N PF00350.18 EEQ29049.1 - 9e-20 71.1 0.0 2.2e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ29049.1 - 4e-06 25.8 0.0 1.6e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region FeoB_N PF02421.13 EEQ29049.1 - 0.00016 20.9 0.2 0.033 13.4 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EEQ29049.1 - 0.0019 18.1 0.0 0.013 15.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ29049.1 - 0.01 16.3 0.1 0.64 10.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NUDIX PF00293.23 EEQ29051.1 - 1.8e-17 63.2 0.1 3.2e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EEQ29051.1 - 4.1e-15 55.9 0.0 4.5e-14 52.5 0.0 2.4 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EEQ29051.1 - 2e-06 27.1 0.5 3.4e-06 26.4 0.3 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Pkinase PF00069.20 EEQ29052.1 - 2.6e-70 236.5 0.0 4.4e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29052.1 - 5.4e-33 114.1 0.0 9.1e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ29052.1 - 0.00013 21.1 0.3 0.00028 20.0 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ29052.1 - 0.0012 17.8 0.4 0.0059 15.5 0.0 2.0 1 1 1 2 2 2 1 Kinase-like DUF4243 PF14027.1 EEQ29053.1 - 2.3e-101 339.5 0.9 2.9e-101 339.1 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) GTP_cyclohydroI PF01227.17 EEQ29055.1 - 6.5e-56 188.4 0.8 8.5e-54 181.5 0.6 2.2 1 1 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EEQ29055.1 - 0.0025 17.7 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein MbeB_N PF04837.7 EEQ29055.1 - 1.1 9.4 4.5 38 4.4 0.1 3.1 3 0 0 3 3 3 0 MbeB-like, N-term conserved region WD40 PF00400.27 EEQ29056.1 - 8.2e-43 142.8 5.2 6e-09 35.4 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEQ29056.1 - 1.7e-30 104.7 0.7 3.9e-30 103.5 0.5 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EEQ29056.1 - 0.19 9.7 4.2 3.3 5.7 0.1 3.2 2 1 0 4 4 4 0 Nucleoporin Nup120/160 XRN_N PF03159.13 EEQ29057.1 - 5.7e-89 297.5 0.1 9.8e-89 296.8 0.1 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus ACT_7 PF13840.1 EEQ29058.1 - 1.8e-22 78.6 0.3 8.7e-15 53.9 0.0 2.7 2 1 0 2 2 2 2 ACT domain WD40 PF00400.27 EEQ29059.1 - 4.4e-30 102.4 20.6 8.7e-08 31.7 0.4 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat PQQ PF01011.16 EEQ29059.1 - 0.0023 17.3 0.3 1.1 8.9 0.0 3.5 5 0 0 5 5 5 2 PQQ enzyme repeat FLgD_tudor PF13861.1 EEQ29059.1 - 2.6 8.1 8.8 23 5.0 0.1 4.1 3 2 2 5 5 5 0 FlgD Tudor-like domain Septin PF00735.13 EEQ29060.1 - 2.3e-114 381.1 0.3 3.7e-114 380.5 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EEQ29060.1 - 1.7e-07 31.2 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ29060.1 - 6.5e-06 25.7 0.3 0.00012 21.5 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEQ29060.1 - 1.7e-05 24.0 0.0 4.9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EEQ29060.1 - 0.0034 17.8 0.1 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EEQ29060.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 EEQ29060.1 - 0.0049 15.9 0.0 0.0095 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.1 EEQ29060.1 - 0.006 16.7 0.8 0.013 15.5 0.0 2.1 2 2 0 2 2 2 1 AAA domain IIGP PF05049.8 EEQ29060.1 - 0.0068 15.2 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 EEQ29060.1 - 0.013 14.7 0.1 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EEQ29060.1 - 0.014 14.8 1.6 0.015 14.7 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EEQ29060.1 - 0.03 13.2 0.4 0.07 12.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 EEQ29060.1 - 0.037 13.4 0.2 0.1 12.0 0.2 1.8 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.18 EEQ29060.1 - 0.04 13.7 5.4 1.2 8.9 0.0 3.1 2 1 1 3 3 3 0 Dynamin family NACHT PF05729.7 EEQ29060.1 - 0.04 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EEQ29060.1 - 0.05 13.9 0.1 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EEQ29060.1 - 0.06 13.3 0.9 0.48 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.4 EEQ29060.1 - 0.076 12.4 0.3 2.9 7.3 0.2 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EEQ29060.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EEQ29060.1 - 0.1 11.5 2.0 0.23 10.4 1.4 1.8 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 EEQ29060.1 - 0.17 11.4 0.6 10 5.5 0.1 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EEQ29060.1 - 0.28 9.9 2.9 0.97 8.1 0.0 2.6 3 0 0 3 3 3 0 ArgK protein Myc-LZ PF02344.10 EEQ29060.1 - 0.63 9.7 5.0 0.83 9.3 0.2 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.27 EEQ29061.1 - 2.4e-46 154.0 38.9 1.7e-11 43.5 0.5 12.6 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 EEQ29061.1 - 1.5e-28 98.8 0.0 2.4e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EEQ29061.1 - 1.2e-07 31.6 1.3 0.024 14.3 0.0 5.6 6 1 1 8 8 8 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEQ29061.1 - 6.4e-07 27.8 8.4 0.11 10.5 0.0 4.9 3 1 0 4 4 4 3 Nucleoporin Nup120/160 IKI3 PF04762.7 EEQ29061.1 - 0.0048 14.7 0.0 1.7 6.3 0.0 2.8 2 1 1 3 3 3 2 IKI3 family Coatomer_WDAD PF04053.9 EEQ29061.1 - 0.054 12.2 0.0 2.5 6.7 0.0 3.2 4 0 0 4 4 4 0 Coatomer WD associated region Cytochrom_D1 PF02239.11 EEQ29061.1 - 0.062 11.5 0.1 1.4 7.1 0.0 3.1 3 1 0 3 3 3 0 Cytochrome D1 heme domain Hemagglutinin PF00509.13 EEQ29061.1 - 0.18 9.9 0.0 0.27 9.3 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin SKIP_SNW PF02731.10 EEQ29062.1 - 3.7e-68 227.9 5.8 3.7e-68 227.9 4.0 2.6 3 0 0 3 3 3 1 SKIP/SNW domain Mito_fiss_reg PF05308.6 EEQ29063.1 - 0.59 9.4 9.2 0.84 8.9 6.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EEQ29063.1 - 2.6 7.2 9.4 3.6 6.7 6.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3395 PF11875.3 EEQ29064.1 - 2.3e-37 127.9 0.0 2.3e-37 127.9 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EEQ29064.1 - 2.5e-15 55.9 0.3 5.2e-15 54.9 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain NAAA-beta PF15508.1 EEQ29065.1 - 3.6e-20 72.1 0.0 4.4e-19 68.6 0.0 2.3 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase BCS1_N PF08740.6 EEQ29066.1 - 6.4e-36 123.7 1.2 1.2e-35 122.8 0.8 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEQ29066.1 - 1.1e-15 58.0 0.0 8.2e-13 48.7 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ29066.1 - 0.0014 19.4 0.0 0.0068 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEQ29066.1 - 0.014 14.7 0.0 0.05 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EEQ29066.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 EEQ29066.1 - 0.058 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 EEQ29066.1 - 0.15 12.0 0.3 0.84 9.6 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain DSPc PF00782.15 EEQ29067.1 - 1.3e-16 60.3 0.0 1.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Glyco_hydro_61 PF03443.9 EEQ29070.1 - 0.00062 19.6 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Chitin_bind_3 PF03067.10 EEQ29070.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Chitin binding domain UPF0029 PF01205.14 EEQ29072.1 - 3.4e-32 110.3 0.3 8.8e-32 109.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EEQ29072.1 - 6.2e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain Pkinase PF00069.20 EEQ29073.1 - 1.6e-12 47.1 0.0 2.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29073.1 - 0.095 11.7 0.0 0.29 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Dynamin_N PF00350.18 EEQ29074.1 - 8.3e-30 103.8 0.1 1.6e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ29074.1 - 4.5e-12 45.3 0.0 9.8e-12 44.2 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 EEQ29074.1 - 1.1e-05 25.1 1.9 0.00057 19.7 0.1 3.0 2 1 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEQ29074.1 - 0.00071 19.5 0.0 0.0032 17.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ29074.1 - 0.0079 16.6 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EEQ29074.1 - 0.22 10.5 1.5 1.5 7.8 0.1 2.5 3 0 0 3 3 3 0 AIG1 family WD40 PF00400.27 EEQ29075.1 - 2.7e-09 36.5 21.3 5.6e-05 22.8 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Mito_carr PF00153.22 EEQ29076.1 - 9.6e-56 185.5 2.6 6.6e-19 67.4 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EEQ29076.1 - 0.00061 19.5 0.2 0.0016 18.2 0.1 1.7 1 0 0 1 1 1 1 UcrQ family Head-tail_con PF12236.3 EEQ29076.1 - 0.02 13.3 0.0 0.029 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein TnpW PF14202.1 EEQ29076.1 - 0.055 13.0 0.2 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpW HMD PF03201.11 EEQ29076.1 - 0.11 12.3 0.0 10 6.1 0.0 3.0 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase SH3_7 PF12914.2 EEQ29077.1 - 0.087 12.6 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 SH3 domain of SH3b2 type Homeobox PF00046.24 EEQ29080.1 - 0.00012 21.5 0.7 0.4 10.3 0.0 3.0 3 0 0 3 3 3 2 Homeobox domain Y_phosphatase3 PF13350.1 EEQ29080.1 - 0.22 11.7 1.2 0.79 9.9 0.0 2.3 3 0 0 3 3 3 0 Tyrosine phosphatase family ERM PF00769.14 EEQ29080.1 - 0.42 10.0 4.1 5.6 6.4 0.1 2.3 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Beta-lactamase PF00144.19 EEQ29082.1 - 3.5e-32 111.7 0.0 5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Ras PF00071.17 EEQ29083.1 - 9e-66 220.2 0.6 1.1e-65 220.0 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ29083.1 - 1.1e-21 77.4 0.0 1.8e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ29083.1 - 1.3e-16 60.3 0.1 1.5e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ29083.1 - 1.7e-05 24.0 0.1 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEQ29083.1 - 5.5e-05 22.6 0.2 0.00012 21.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ29083.1 - 6.5e-05 22.8 0.0 9.5e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EEQ29083.1 - 0.00026 21.1 0.1 0.1 12.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EEQ29083.1 - 0.00073 18.8 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EEQ29083.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EEQ29083.1 - 0.003 16.8 0.1 0.019 14.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EEQ29083.1 - 0.0081 15.3 0.0 0.022 13.9 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ29083.1 - 0.019 14.9 0.1 0.064 13.2 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EEQ29083.1 - 0.027 14.3 0.1 0.082 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EEQ29083.1 - 0.029 13.3 0.1 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EEQ29083.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EEQ29083.1 - 0.053 13.8 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EEQ29083.1 - 0.057 13.1 0.1 0.13 12.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EEQ29083.1 - 0.084 12.3 0.1 0.93 8.9 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M1 PF01433.15 EEQ29084.1 - 1.6e-126 422.5 0.3 2.5e-126 421.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EEQ29084.1 - 5.1e-80 269.1 0.0 7.5e-80 268.5 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EEQ29084.1 - 4.6e-22 78.4 1.8 9e-22 77.4 1.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Ssl1 PF04056.9 EEQ29085.1 - 8.1e-73 244.1 0.0 1.1e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EEQ29085.1 - 1.3e-15 57.1 14.2 1.3e-15 57.1 9.8 2.8 1 1 1 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EEQ29085.1 - 4.7e-09 36.5 0.0 6.8e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EEQ29085.1 - 0.0012 18.1 4.3 0.0012 18.1 3.0 2.2 2 0 0 2 2 2 1 Transcription factor Tfb4 Integrase_Zn PF02022.14 EEQ29085.1 - 0.034 13.5 0.6 0.21 11.0 0.0 2.3 2 0 0 2 2 2 0 Integrase Zinc binding domain NUDIX PF00293.23 EEQ29086.1 - 3.2e-06 26.8 0.1 4.1e-06 26.4 0.1 1.3 1 1 0 1 1 1 1 NUDIX domain DUF1918 PF08940.6 EEQ29086.1 - 0.025 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) PUF PF00806.14 EEQ29088.1 - 5.6e-36 120.0 1.1 4.8e-06 25.7 0.0 8.7 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat RraB PF06877.6 EEQ29088.1 - 0.073 13.7 0.1 0.26 11.9 0.0 1.9 2 0 0 2 2 2 0 Regulator of ribonuclease activity B FliJ PF02050.11 EEQ29088.1 - 1.8 8.5 9.3 0.97 9.4 0.9 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Peptidase_S9 PF00326.16 EEQ29089.1 - 3.9e-05 22.9 0.2 6.9e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family TPT PF03151.11 EEQ29090.1 - 1.4e-38 131.9 4.4 1.4e-38 131.9 3.0 2.2 2 1 1 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EEQ29090.1 - 4.4e-07 29.1 19.3 7.2e-06 25.1 13.4 2.1 1 1 0 1 1 1 1 UAA transporter family PSII PF00421.14 EEQ29090.1 - 0.001 17.7 1.9 0.0018 16.9 1.3 1.3 1 0 0 1 1 1 1 Photosystem II protein EamA PF00892.15 EEQ29090.1 - 0.035 14.1 37.3 0.018 15.0 7.9 3.3 3 2 0 3 3 3 0 EamA-like transporter family DUF1352 PF07086.7 EEQ29090.1 - 2.4 7.7 5.8 0.45 10.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1352) Molybdopterin PF00384.17 EEQ29091.1 - 2.4e-70 237.4 0.0 7.1e-68 229.3 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EEQ29091.1 - 4.3e-19 67.4 0.1 1.3e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 EEQ29091.1 - 1.7e-18 66.1 0.1 5.1e-18 64.6 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 EEQ29091.1 - 4.4e-14 52.3 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EEQ29091.1 - 4.3e-08 32.7 0.6 4.3e-08 32.7 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_19 PF06902.6 EEQ29091.1 - 0.075 12.8 1.6 1.1 9.1 1.1 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster TPP_enzyme_M PF00205.17 EEQ29091.1 - 0.094 12.4 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EEQ29091.1 - 0.11 12.1 1.1 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain XRCC4 PF06632.7 EEQ29092.1 - 2.1e-10 40.0 9.8 3.5e-10 39.2 6.8 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 EEQ29092.1 - 0.0043 16.8 2.9 0.011 15.6 2.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) CVNH PF08881.5 EEQ29092.1 - 0.043 14.0 0.9 0.088 13.0 0.1 1.8 2 0 0 2 2 2 0 CVNH domain tRNA-synt_1g PF09334.6 EEQ29092.1 - 0.061 11.9 0.4 0.082 11.5 0.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) HSCB_C PF07743.8 EEQ29092.1 - 2.6 8.5 9.8 0.68 10.4 0.6 2.7 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4407 PF14362.1 EEQ29092.1 - 5.6 5.8 9.1 9.8 5.0 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF904 PF06005.7 EEQ29092.1 - 7.9 6.8 10.4 1.6 9.1 4.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF904) zf-H2C2 PF09337.5 EEQ29096.1 - 0.014 14.7 0.4 0.032 13.6 0.3 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger ER_lumen_recept PF00810.13 EEQ29097.1 - 9.2e-47 159.2 6.3 1.5e-46 158.5 4.4 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EEQ29097.1 - 2.4 7.7 9.3 0.93 9.0 0.1 3.5 4 1 0 4 4 4 0 PQ loop repeat DUF485 PF04341.7 EEQ29097.1 - 5.9 6.6 7.2 0.8 9.4 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF485 DUF382 PF04037.8 EEQ29099.1 - 1.1e-61 206.3 1.2 1.1e-61 206.3 0.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EEQ29099.1 - 4.5e-21 73.9 6.2 1.1e-20 72.7 4.3 1.7 1 0 0 1 1 1 1 PSP MRP-S33 PF08293.6 EEQ29100.1 - 7.1e-33 112.4 0.2 8.9e-33 112.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF4070 PF13282.1 EEQ29100.1 - 0.045 13.2 0.2 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) Ribonuclease_3 PF00636.21 EEQ29101.1 - 5.5e-14 52.5 0.0 1.8e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEQ29101.1 - 2.6e-11 43.6 0.0 3.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EEQ29101.1 - 0.32 11.6 0.0 0.32 11.6 0.0 2.3 2 0 0 2 2 2 0 Double-stranded RNA binding motif RTA1 PF04479.8 EEQ29102.1 - 1.3e-38 132.7 1.6 1.9e-38 132.1 1.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.3 EEQ29103.1 - 6e-08 31.6 0.1 9.2e-08 31.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IRS PF02174.12 EEQ29103.1 - 0.045 13.3 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Abhydrolase_6 PF12697.2 EEQ29104.1 - 5.1e-32 111.5 0.0 6.3e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ29104.1 - 1.1e-20 74.1 0.0 1.6e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ29104.1 - 6.1e-16 58.4 0.0 1.5e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ29104.1 - 1.2e-08 34.8 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EEQ29104.1 - 8.3e-05 22.9 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.9 EEQ29104.1 - 0.00013 20.5 0.0 0.00035 19.1 0.0 1.6 2 0 0 2 2 2 1 Ndr family Esterase PF00756.15 EEQ29104.1 - 0.00015 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 EEQ29104.1 - 0.00067 19.2 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.3 EEQ29104.1 - 0.0021 17.8 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 EEQ29104.1 - 0.0096 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EEQ29104.1 - 0.028 13.8 0.0 0.6 9.5 0.0 2.2 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.7 EEQ29104.1 - 0.046 13.4 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.6 EEQ29104.1 - 0.05 12.3 0.0 0.076 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF3089 PF11288.3 EEQ29104.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF915 PF06028.6 EEQ29104.1 - 0.063 12.3 0.0 3.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 EEQ29104.1 - 0.08 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_S3Ae PF01015.13 EEQ29105.1 - 3.4e-77 258.1 7.1 4.2e-77 257.8 4.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family GTP_CH_N PF12471.3 EEQ29106.1 - 3.3e-65 219.3 0.1 3.5e-50 170.3 0.0 2.3 1 1 1 2 2 2 2 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EEQ29106.1 - 1.6e-17 63.2 0.0 2.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.8 EEQ29107.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like UPRTase PF14681.1 EEQ29108.1 - 5.6e-79 264.1 0.0 7e-79 263.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEQ29108.1 - 0.0028 17.3 0.0 0.0038 16.9 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EEQ29108.1 - 0.15 11.7 0.5 0.31 10.7 0.4 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.8 EEQ29109.1 - 2.5e-34 118.5 3.5 2.9e-34 118.3 1.6 1.6 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin Baculo_PEP_C PF04513.7 EEQ29110.1 - 0.0066 16.2 8.0 0.0066 16.2 5.5 2.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EEQ29110.1 - 0.025 14.4 5.3 0.29 10.9 0.1 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlxA PF14282.1 EEQ29110.1 - 0.8 9.6 9.9 3.2 7.7 0.7 3.0 2 1 0 2 2 2 0 FlxA-like protein Laminin_II PF06009.7 EEQ29110.1 - 6.4 6.5 10.4 5 6.8 0.6 3.1 1 1 2 3 3 3 0 Laminin Domain II Ras PF00071.17 EEQ29111.1 - 3.8e-46 156.4 0.2 4.3e-46 156.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ29111.1 - 6.3e-16 58.9 0.1 8.9e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ29111.1 - 5.4e-07 29.0 0.0 6.6e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEQ29111.1 - 3.5e-06 26.9 0.0 4.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ29111.1 - 1.2e-05 24.8 0.2 0.00037 19.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EEQ29111.1 - 0.00079 18.6 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EEQ29111.1 - 0.084 12.1 0.1 0.37 10.0 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B tRNA-synt_2b PF00587.20 EEQ29112.1 - 2.8e-24 85.6 0.0 4.3e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EEQ29112.1 - 1.9e-18 66.4 4.5 1.9e-18 66.4 3.1 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 EEQ29112.1 - 0.034 13.8 2.5 0.078 12.6 1.7 1.6 1 0 0 1 1 1 0 Mnd1 family 2-Hacid_dh_C PF02826.14 EEQ29113.1 - 7.7e-50 168.5 0.0 1.2e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ29113.1 - 1.3e-33 115.2 0.0 1.9e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEQ29113.1 - 5.9e-05 22.9 0.3 0.00014 21.7 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EEQ29113.1 - 0.00014 21.2 0.2 0.00039 19.8 0.0 1.8 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.16 EEQ29113.1 - 0.0018 18.1 0.1 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EEQ29113.1 - 0.0033 16.8 0.1 0.0095 15.3 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EEQ29113.1 - 0.13 11.8 1.5 1.2 8.7 0.4 2.5 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 EEQ29114.1 - 4.6e-67 225.9 0.0 5.5e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29114.1 - 3.5e-31 108.2 0.0 4.8e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ29114.1 - 0.053 12.4 0.0 0.087 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like G_glu_transpept PF01019.16 EEQ29115.1 - 3.5e-85 286.4 0.0 4.8e-53 180.4 0.0 2.1 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase NADH_B2 PF14813.1 EEQ29117.1 - 0.00069 19.2 0.2 0.00073 19.1 0.1 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 HAD PF12710.2 EEQ29118.1 - 7.8e-34 117.5 0.0 1.7e-33 116.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEQ29118.1 - 1.7e-28 99.2 0.0 3.4e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ29118.1 - 7.2e-19 69.0 0.0 8.3e-18 65.5 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EEQ29118.1 - 1.1e-18 67.1 1.0 9.2e-14 51.3 0.6 2.6 1 1 1 2 2 2 2 P5-type ATPase cation transporter Cation_ATPase_N PF00690.21 EEQ29118.1 - 0.0014 18.0 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EEQ29118.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ29118.1 - 0.0038 16.8 0.0 0.51 9.8 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase NAP PF00956.13 EEQ29119.1 - 2.6e-85 285.4 5.8 2.6e-85 285.4 4.0 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 EEQ29119.1 - 0.57 10.0 27.6 0.032 14.1 9.4 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 EEQ29119.1 - 4.6 5.8 35.4 0.39 9.4 19.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Myosin_head PF00063.16 EEQ29120.1 - 1.7e-245 816.3 1.7 2.4e-245 815.8 1.2 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EEQ29120.1 - 9.5e-35 118.6 3.2 2.9e-34 117.0 2.2 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EEQ29120.1 - 1.6e-12 45.8 30.8 6.1e-05 22.3 0.4 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_22 PF13401.1 EEQ29120.1 - 0.00027 21.1 0.1 0.0023 18.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain GAS PF13851.1 EEQ29120.1 - 0.003 16.8 14.8 0.003 16.8 10.2 2.7 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding AAA_16 PF13191.1 EEQ29120.1 - 0.0034 17.3 0.4 0.15 12.0 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EEQ29120.1 - 0.0057 15.5 0.0 0.014 14.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Myosin_N PF02736.14 EEQ29120.1 - 0.0069 16.0 2.4 0.016 14.8 1.7 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EEQ29120.1 - 0.022 14.5 0.0 0.062 13.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EEQ29120.1 - 0.034 13.5 1.5 0.14 11.5 0.0 2.7 3 1 0 3 3 3 0 AAA-like domain DUF258 PF03193.11 EEQ29120.1 - 0.065 12.4 0.0 0.18 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2422 PF10337.4 EEQ29120.1 - 0.15 10.8 3.4 0.25 10.0 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) FlaC_arch PF05377.6 EEQ29120.1 - 0.35 10.7 7.7 0.62 10.0 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DegQ PF08181.6 EEQ29120.1 - 1.6 8.4 11.2 0.029 14.1 0.8 3.1 3 0 0 3 3 3 0 DegQ (SacQ) family IncA PF04156.9 EEQ29120.1 - 4.6 6.7 27.7 0.51 9.9 5.4 2.6 1 1 1 2 2 2 0 IncA protein Ham1p_like PF01725.11 EEQ29121.1 - 1.4e-51 174.5 0.0 1.6e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EEQ29122.1 - 2.8e-27 95.5 0.3 4.9e-27 94.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEQ29122.1 - 1.6e-12 48.3 0.6 3.2e-12 47.3 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEQ29122.1 - 0.00073 19.5 0.5 0.0011 18.9 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EEQ29122.1 - 0.00076 19.6 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEQ29122.1 - 0.0018 18.1 0.0 0.0053 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEQ29122.1 - 0.0026 17.9 0.0 0.0053 16.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EEQ29122.1 - 0.0027 16.9 0.0 0.0076 15.4 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NTPase_1 PF03266.10 EEQ29122.1 - 0.0055 16.4 0.1 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.1 EEQ29122.1 - 0.006 16.4 0.0 0.065 13.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ29122.1 - 0.0065 16.4 0.1 0.017 15.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain ADK PF00406.17 EEQ29122.1 - 0.019 14.8 0.1 0.19 11.5 0.0 2.1 2 1 0 2 2 2 0 Adenylate kinase RNA_helicase PF00910.17 EEQ29122.1 - 0.045 13.9 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EEQ29122.1 - 0.048 13.1 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EEQ29122.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Cytidylate_kin2 PF13189.1 EEQ29122.1 - 0.077 12.9 0.1 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_3 PF07726.6 EEQ29122.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EEQ29122.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family KaiC PF06745.8 EEQ29122.1 - 0.15 11.1 0.1 0.41 9.7 0.0 1.7 2 0 0 2 2 2 0 KaiC Peptidase_C78 PF07910.8 EEQ29123.1 - 1.3e-65 220.6 0.0 1.6e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 EEQ29123.1 - 0.0029 17.6 5.7 0.069 13.2 1.8 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DUF4542 PF15075.1 EEQ29123.1 - 0.083 12.8 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) zf-C2H2 PF00096.21 EEQ29123.1 - 0.17 12.2 3.6 8.1 7.0 1.8 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type AA_kinase PF00696.23 EEQ29124.1 - 7.5e-42 143.5 0.1 1.4e-41 142.6 0.0 1.5 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 EEQ29124.1 - 1.1e-13 50.4 1.2 1e-11 44.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EEQ29124.1 - 9e-13 47.4 0.3 1.2e-10 40.5 0.1 2.9 2 0 0 2 2 2 2 ACT domain zf-Tim10_DDP PF02953.10 EEQ29125.1 - 6.4e-23 79.8 1.0 8.2e-23 79.4 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Arif-1 PF06770.6 EEQ29125.1 - 0.15 11.4 0.8 0.19 11.1 0.5 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) G10 PF01125.12 EEQ29126.1 - 7e-66 220.2 4.2 7.8e-66 220.0 2.9 1.0 1 0 0 1 1 1 1 G10 protein Fork_head PF00250.13 EEQ29127.1 - 3.9e-34 116.5 0.0 7.3e-34 115.6 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Ribosomal_L23eN PF03939.8 EEQ29128.1 - 8.6e-23 80.1 9.1 1.7e-22 79.1 6.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EEQ29128.1 - 5.7e-14 51.8 1.9 8.3e-14 51.3 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 DUF3321 PF11968.3 EEQ29129.1 - 4.9e-86 287.8 0.0 5.9e-86 287.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) 5-nucleotidase PF06189.7 EEQ29129.1 - 0.097 11.4 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 5'-nucleotidase Pkinase PF00069.20 EEQ29130.1 - 9.8e-25 87.1 0.0 1.3e-23 83.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29130.1 - 0.0022 17.0 0.0 0.07 12.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase eRF1_2 PF03464.10 EEQ29131.1 - 4e-46 156.6 0.1 6.7e-46 155.9 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EEQ29131.1 - 3.1e-39 133.7 0.2 6.3e-39 132.7 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EEQ29131.1 - 1.9e-28 98.6 0.0 3.2e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 PDT PF00800.13 EEQ29132.1 - 2.4e-62 209.7 0.1 3.3e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EEQ29132.1 - 4.9e-05 22.7 0.0 0.00018 20.9 0.0 2.0 1 1 0 1 1 1 1 ACT domain MaoC_dehydratas PF01575.14 EEQ29133.1 - 0.00035 19.9 0.0 0.00067 19.0 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain Abhydrolase_3 PF07859.8 EEQ29134.1 - 9.5e-43 146.2 0.0 2.2e-31 109.0 0.0 2.4 2 1 0 3 3 3 2 alpha/beta hydrolase fold COesterase PF00135.23 EEQ29134.1 - 0.00037 19.3 0.6 0.0028 16.4 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.4 EEQ29134.1 - 0.079 12.1 0.2 1.8 7.7 0.1 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase DER1 PF04511.10 EEQ29135.1 - 2.3e-31 108.8 2.0 2.7e-31 108.6 1.4 1.0 1 0 0 1 1 1 1 Der1-like family Urm1 PF09138.6 EEQ29137.1 - 0.013 15.6 0.0 0.066 13.3 0.0 2.0 1 1 1 2 2 2 0 Urm1 (Ubiquitin related modifier) GMAP PF06540.6 EEQ29137.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Galanin message associated peptide (GMAP) TruB_N PF01509.13 EEQ29138.1 - 1.4e-21 77.1 5.2 3.6e-19 69.3 0.2 4.2 2 2 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EEQ29138.1 - 3.4e-21 74.7 1.4 7.3e-21 73.6 1.0 1.6 1 0 0 1 1 1 1 PUA domain DUF4407 PF14362.1 EEQ29138.1 - 0.92 8.4 12.7 1.5 7.7 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_polI_A34 PF08208.6 EEQ29138.1 - 7.2 6.2 32.6 11 5.6 22.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EEQ29138.1 - 7.9 5.5 19.0 12 4.9 13.2 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Spc7 PF08317.6 EEQ29140.1 - 0.00049 18.8 8.1 0.00049 18.8 5.6 2.3 2 0 0 2 2 2 1 Spc7 kinetochore protein GPAT_N PF14829.1 EEQ29140.1 - 0.026 14.2 0.2 1.1 8.9 0.0 3.0 2 1 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal FliJ PF02050.11 EEQ29140.1 - 0.026 14.5 1.8 0.026 14.5 1.2 4.1 3 2 1 4 4 4 0 Flagellar FliJ protein DUF812 PF05667.6 EEQ29140.1 - 0.03 12.8 15.4 0.049 12.1 9.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF16 PF01519.11 EEQ29140.1 - 0.66 10.2 7.9 4 7.7 5.3 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 COG2 PF06148.6 EEQ29140.1 - 0.78 9.6 10.3 2.6 7.9 0.5 3.5 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 RmuC PF02646.11 EEQ29140.1 - 0.89 8.3 10.6 0.47 9.2 3.3 2.6 2 1 1 3 3 3 0 RmuC family Helicase_IV_N PF12462.3 EEQ29140.1 - 1.7 8.2 9.3 0.1 12.2 0.9 2.9 3 1 1 4 4 4 0 DNA helicase IV / RNA helicase N terminal FlaC_arch PF05377.6 EEQ29140.1 - 4.2 7.3 6.6 8.3 6.3 0.3 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EEQ29140.1 - 5 6.9 11.7 3.6 7.4 2.0 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.13 EEQ29140.1 - 6.2 6.2 14.8 1.8 8.0 5.5 2.9 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.7 EEQ29140.1 - 8.6 6.6 17.9 0.78 10.0 2.5 4.5 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein HET PF06985.6 EEQ29141.1 - 3e-09 37.1 0.2 7.3e-09 35.9 0.2 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CLTH PF10607.4 EEQ29142.1 - 8.4e-33 113.0 0.7 1.3e-32 112.5 0.1 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DUF2431 PF10354.4 EEQ29143.1 - 2e-45 154.7 0.0 5.4e-29 101.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) p47_phox_C PF08944.6 EEQ29143.1 - 0.011 15.9 0.3 0.038 14.1 0.2 2.0 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain UAA PF08449.6 EEQ29144.1 - 8.5e-13 47.8 21.2 1.1e-12 47.5 14.7 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEQ29144.1 - 8.7e-11 41.6 6.6 8.7e-11 41.6 4.6 2.9 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EEQ29144.1 - 0.0019 18.2 5.7 0.0019 18.2 4.0 2.4 2 0 0 2 2 2 1 EamA-like transporter family Nol1_Nop2_Fmu PF01189.12 EEQ29145.1 - 2.3e-95 319.2 0.0 3.8e-95 318.5 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EEQ29145.1 - 0.0032 17.4 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Blt1 PF12754.2 EEQ29146.1 - 1e-37 130.4 1.0 4e-31 108.7 0.0 2.0 1 1 1 2 2 2 2 Cell-cycle control medial ring component DUF2340 PF10209.4 EEQ29146.1 - 0.018 15.1 0.1 0.05 13.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) Pyridox_ox_2 PF12900.2 EEQ29146.1 - 0.038 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Striatin PF08232.7 EEQ29147.1 - 5.3e-43 146.5 4.4 5.3e-43 146.5 3.0 2.7 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 EEQ29147.1 - 1.4e-32 110.3 17.0 3.1e-06 26.8 0.0 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEQ29147.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEQ29147.1 - 0.14 10.4 0.2 0.28 9.4 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain PAT1 PF09770.4 EEQ29147.1 - 4.4 5.4 29.1 6 4.9 20.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 XPA_C PF05181.7 EEQ29148.1 - 1.3e-29 101.5 2.5 3.5e-29 100.1 1.7 1.8 1 0 0 1 1 1 1 XPA protein C-terminus YhfH PF14149.1 EEQ29148.1 - 0.0023 17.6 3.2 0.26 11.1 0.1 2.5 2 0 0 2 2 2 2 YhfH-like protein DUF2406 PF10295.4 EEQ29148.1 - 0.0098 16.3 0.2 0.034 14.6 0.1 2.0 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) ArfGap PF01412.13 EEQ29148.1 - 0.38 10.5 3.7 1.7 8.4 1.0 2.6 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Fer4_17 PF13534.1 EEQ29148.1 - 1.6 9.1 5.2 76 3.7 2.9 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain OrfB_Zn_ribbon PF07282.6 EEQ29148.1 - 6 6.6 6.4 59 3.4 2.5 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain XPA_N PF01286.13 EEQ29148.1 - 6.7 6.4 10.9 0.77 9.4 3.9 1.9 2 0 0 2 2 2 0 XPA protein N-terminal PIG-P PF08510.7 EEQ29149.1 - 6.4e-44 148.6 0.1 6.4e-44 148.6 0.1 2.5 3 1 0 3 3 3 1 PIG-P CDC45 PF02724.9 EEQ29149.1 - 0.0033 15.5 0.2 0.0046 15.0 0.2 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.5 EEQ29149.1 - 0.36 9.8 8.0 0.45 9.5 5.5 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EEQ29149.1 - 0.45 8.3 11.1 0.53 8.1 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 EEQ29149.1 - 0.45 9.6 7.6 0.75 8.9 5.3 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DPM2 PF07297.7 EEQ29149.1 - 2.6 8.4 8.8 5.6 7.3 6.1 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) HsbA PF12296.3 EEQ29150.1 - 1.3e-32 112.2 5.4 1.3e-32 112.2 3.8 2.1 2 1 1 3 3 3 1 Hydrophobic surface binding protein A Phage_Coat_B PF05356.6 EEQ29150.1 - 0.09 12.4 1.5 0.21 11.3 0.8 1.8 2 0 0 2 2 2 0 Phage Coat protein B DUF3216 PF11505.3 EEQ29150.1 - 0.15 11.9 0.3 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) Abhydrolase_6 PF12697.2 EEQ29152.1 - 6.2e-14 52.4 0.5 8.3e-14 52.0 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ29152.1 - 9.3e-07 28.6 0.0 1.5e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ29152.1 - 1e-05 25.3 0.0 1.7e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EEQ29152.1 - 0.062 13.2 0.1 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus UCH PF00443.24 EEQ29153.1 - 2.5e-12 46.4 0.0 5.5e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.1 EEQ29153.1 - 8.3e-11 41.3 11.4 1.5e-10 40.6 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.15 EEQ29153.1 - 3e-06 26.6 23.0 0.023 14.3 3.3 4.5 4 0 0 4 4 4 3 MORN repeat zf-C3HC4_2 PF13923.1 EEQ29153.1 - 0.00058 19.8 11.4 0.00073 19.5 6.4 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ29153.1 - 0.13 11.9 12.1 0.27 10.9 8.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.20 EEQ29154.1 - 1.7e-10 40.5 0.0 2.2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29154.1 - 6.4e-07 28.7 0.0 1.5e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ29154.1 - 8.7e-05 22.3 0.5 0.00031 20.5 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ29154.1 - 0.00013 21.3 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EEQ29154.1 - 0.0006 19.4 0.0 0.0018 17.9 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 EEQ29154.1 - 0.00066 18.8 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ29154.1 - 0.0024 16.9 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EEQ29154.1 - 0.0091 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 DUF2066 PF09839.4 EEQ29154.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) GH3 PF03321.8 EEQ29155.1 - 1.8e-05 23.4 0.0 0.0063 15.0 0.0 2.1 2 0 0 2 2 2 2 GH3 auxin-responsive promoter Beta_elim_lyase PF01212.16 EEQ29156.1 - 1.7e-57 194.8 0.0 2.1e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEQ29156.1 - 0.0057 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EEQ29156.1 - 0.015 14.2 0.0 0.019 13.9 0.0 1.3 1 1 0 1 1 1 0 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEQ29156.1 - 0.024 12.9 0.0 0.046 12.0 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.11 EEQ29157.1 - 5e-39 134.0 26.1 5e-39 134.0 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ29157.1 - 1.3e-15 57.0 1.4 1.3e-15 57.0 1.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Methyltransf_2 PF00891.13 EEQ29158.1 - 1.6e-30 106.1 0.0 1.9e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase p450 PF00067.17 EEQ29159.1 - 4.1e-48 164.0 0.0 5.9e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyt-b5 PF00173.23 EEQ29160.1 - 1.6e-15 56.6 0.0 3.1e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA_8 PF12780.2 EEQ29160.1 - 0.095 11.6 0.2 0.21 10.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 ABC2_membrane PF01061.19 EEQ29161.1 - 2.6e-88 294.6 61.1 1.2e-46 158.5 17.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EEQ29161.1 - 1.5e-30 104.8 13.0 1.1e-28 98.8 0.2 3.0 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EEQ29161.1 - 9.6e-23 81.0 0.0 2.4e-14 53.8 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EEQ29161.1 - 4.8e-17 61.8 0.1 1e-16 60.8 0.1 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EEQ29161.1 - 0.00021 20.4 41.8 0.042 12.8 8.9 2.9 2 2 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.14 EEQ29161.1 - 0.032 13.4 0.0 2.4 7.3 0.0 2.9 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Fungal_trans PF04082.13 EEQ29162.1 - 3.7e-06 25.9 0.3 7.5e-06 25.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain HSBP1 PF06825.7 EEQ29162.1 - 0.068 12.7 0.4 0.068 12.7 0.3 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DS PF01916.12 EEQ29163.1 - 1.9e-142 473.7 0.0 2.2e-142 473.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EEQ29163.1 - 0.1 11.7 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Carbamoyltransferase Myb_DNA-binding PF00249.26 EEQ29164.1 - 2.9e-16 59.2 0.0 2.8e-09 36.8 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ29164.1 - 9e-06 25.7 0.0 0.056 13.5 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain HeLo PF14479.1 EEQ29166.1 - 3.2e-54 183.9 0.5 3.2e-54 183.9 0.3 1.8 2 0 0 2 2 2 1 Prion-inhibition and propagation TPR_10 PF13374.1 EEQ29166.1 - 7e-47 156.0 8.2 2.5e-07 30.4 0.1 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ29166.1 - 1.1e-42 143.8 11.8 1.2e-10 41.1 0.0 5.4 2 1 1 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ29166.1 - 1.1e-09 37.4 13.4 0.24 11.3 0.8 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ29166.1 - 4.1e-09 35.5 11.3 0.41 10.5 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EEQ29166.1 - 6.9e-07 29.3 0.4 0.025 14.6 0.1 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.17 EEQ29166.1 - 1.7e-06 27.1 0.0 3.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 EEQ29166.1 - 9.4e-06 25.1 10.1 0.043 13.4 0.3 5.1 2 2 3 5 5 5 3 TPR repeat TPR_16 PF13432.1 EEQ29166.1 - 6.3e-05 23.5 2.9 0.56 10.9 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ29166.1 - 0.00044 19.7 11.2 3 7.5 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ29166.1 - 0.0023 18.2 14.4 0.037 14.3 0.8 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ29166.1 - 0.0024 18.3 13.2 19 6.2 0.1 7.3 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ29166.1 - 0.0044 17.0 2.2 1.3e+02 3.1 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ29166.1 - 0.01 16.1 12.5 0.54 10.8 0.5 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ29166.1 - 0.052 13.3 5.0 59 3.7 0.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat NmrA PF05368.8 EEQ29167.1 - 2.1e-54 184.2 0.1 2.7e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ29167.1 - 5e-16 59.2 0.1 8.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEQ29167.1 - 3.9e-07 29.0 0.3 5.5e-07 28.5 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EEQ29167.1 - 0.0077 16.2 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain AIG1 PF04548.11 EEQ29167.1 - 0.053 12.6 0.2 0.082 12.0 0.1 1.2 1 0 0 1 1 1 0 AIG1 family Saccharop_dh PF03435.13 EEQ29167.1 - 0.055 12.4 0.3 0.098 11.6 0.2 1.5 1 1 1 2 2 2 0 Saccharopine dehydrogenase Ank_2 PF12796.2 EEQ29171.1 - 9.3e-74 243.8 0.3 1.5e-18 66.9 0.4 6.6 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ29171.1 - 1.5e-65 213.9 17.3 3.7e-10 39.0 0.2 12.7 13 0 0 13 13 13 9 Ankyrin repeat Ank_3 PF13606.1 EEQ29171.1 - 3e-51 166.2 8.4 1.3e-05 24.9 0.1 14.0 14 0 0 14 14 14 8 Ankyrin repeat Ank_4 PF13637.1 EEQ29171.1 - 1.8e-50 168.4 3.8 2.3e-08 34.3 0.0 10.0 3 1 7 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ29171.1 - 4.1e-44 147.6 9.8 9.2e-11 41.6 0.0 9.5 5 2 6 11 11 11 8 Ankyrin repeats (many copies) NACHT PF05729.7 EEQ29171.1 - 7.6e-09 35.4 0.1 1.8e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEQ29171.1 - 5.8e-07 29.6 0.0 1.7e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ29171.1 - 0.00028 21.0 0.0 0.00072 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEQ29171.1 - 0.00065 19.2 0.1 0.0018 17.7 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EEQ29171.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 EEQ29171.1 - 0.024 13.5 0.0 0.062 12.1 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 EEQ29171.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 EEQ29171.1 - 0.13 11.9 0.1 0.36 10.5 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_M35 PF02102.10 EEQ29172.1 - 4.5e-105 351.2 16.5 5e-105 351.0 11.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EEQ29172.1 - 1.9e-06 28.4 1.4 3.3e-06 27.6 0.4 1.8 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase DsrD PF08679.6 EEQ29172.1 - 0.079 12.9 0.3 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) DUF544 PF04424.8 EEQ29173.1 - 3.6e-09 36.4 0.0 6.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Gcd10p PF04189.8 EEQ29174.1 - 5.4e-88 294.9 0.0 8.3e-88 294.3 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family APH PF01636.18 EEQ29177.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.2 EEQ29178.1 - 1.4e-26 92.6 0.0 2.2e-10 40.7 0.0 3.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ29178.1 - 2.9e-24 84.9 0.8 5.7e-06 26.6 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EEQ29178.1 - 1.1e-20 72.3 0.4 0.002 17.8 0.0 6.9 7 1 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EEQ29178.1 - 2.2e-15 56.3 3.7 0.0021 18.2 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ29178.1 - 3.4e-13 48.4 0.6 2.4 8.6 0.0 7.2 8 0 0 8 8 8 5 Ankyrin repeat Pectate_lyase_3 PF12708.2 EEQ29179.1 - 9.8e-83 277.6 13.1 2.2e-67 227.4 4.1 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EEQ29179.1 - 2.4e-06 26.9 1.1 0.048 13.1 0.0 3.4 4 0 0 4 4 4 2 N terminal extension of bacteriophage endosialidase LysM PF01476.15 EEQ29179.1 - 9.6e-06 25.3 0.1 0.4 10.6 0.0 3.7 3 0 0 3 3 3 2 LysM domain Glyco_hydro_18 PF00704.23 EEQ29180.1 - 7.2e-61 206.5 0.1 1.1e-60 205.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 EST1_DNA_bind PF10373.4 EEQ29180.1 - 0.19 10.8 0.0 0.37 9.9 0.0 1.4 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain DUF4131 PF13567.1 EEQ29181.1 - 3.7 6.9 7.8 0.45 9.9 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) CMAS PF02353.15 EEQ29182.1 - 1.2e-18 67.1 0.0 1.6e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EEQ29182.1 - 1.9e-18 66.7 0.1 2.7e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ29182.1 - 2.9e-18 66.1 0.2 5e-18 65.3 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ29182.1 - 1.8e-15 56.8 0.0 2.3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ29182.1 - 7.5e-15 55.4 0.0 1.1e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ29182.1 - 9.7e-14 51.6 0.1 1.4e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ29182.1 - 5.9e-13 48.8 0.0 9.5e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ29182.1 - 5.1e-09 35.5 0.0 1.2e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EEQ29182.1 - 2.7e-08 34.0 0.0 4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ29182.1 - 5.4e-07 29.3 0.0 7.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EEQ29182.1 - 1.4e-06 27.7 0.1 2.1e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EEQ29182.1 - 5.6e-06 26.0 0.2 7.6e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 EEQ29182.1 - 5.6e-06 25.6 0.0 7.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EEQ29182.1 - 1.4e-05 24.7 0.1 1.9e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TehB PF03848.9 EEQ29182.1 - 2e-05 23.8 0.0 2.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 EEQ29182.1 - 0.00019 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.6 EEQ29182.1 - 0.0004 19.9 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) UPF0020 PF01170.13 EEQ29182.1 - 0.00042 19.9 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 EEQ29182.1 - 0.0011 18.0 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase N2227 PF07942.7 EEQ29182.1 - 0.0012 17.8 0.1 0.081 11.8 0.0 2.1 1 1 1 2 2 2 1 N2227-like protein Methyltransf_9 PF08003.6 EEQ29182.1 - 0.0019 16.9 0.0 0.0025 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) GCD14 PF08704.5 EEQ29182.1 - 0.0028 17.1 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_29 PF03141.11 EEQ29182.1 - 0.011 14.0 0.0 0.014 13.7 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 EEQ29182.1 - 0.013 16.2 0.2 0.037 14.8 0.1 1.8 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 EEQ29182.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EEQ29182.1 - 0.13 11.5 0.1 0.42 9.8 0.1 1.7 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.4 EEQ29182.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase NmrA PF05368.8 EEQ29183.1 - 3.3e-18 65.8 0.1 5.1e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ29183.1 - 1.1e-15 58.0 0.1 1.8e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EEQ29183.1 - 3.5e-09 36.1 0.3 5e-09 35.6 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EEQ29183.1 - 9e-07 28.8 0.2 1.6e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EEQ29183.1 - 1.2e-05 25.5 0.1 2.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EEQ29183.1 - 6.4e-05 22.4 0.1 0.00011 21.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ29183.1 - 0.00013 20.7 0.1 0.00021 20.0 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EEQ29183.1 - 0.00063 19.7 0.8 0.0013 18.7 0.6 1.5 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.12 EEQ29183.1 - 0.0044 15.9 0.3 0.007 15.2 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 EEQ29183.1 - 0.0075 16.6 0.4 0.015 15.7 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 EEQ29183.1 - 0.0088 14.9 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EEQ29183.1 - 0.012 14.5 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Gp_dh_N PF00044.19 EEQ29183.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain adh_short PF00106.20 EEQ29183.1 - 0.029 14.2 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GFO_IDH_MocA PF01408.17 EEQ29183.1 - 0.05 14.1 0.2 0.086 13.3 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.5 EEQ29183.1 - 0.068 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.15 EEQ29183.1 - 0.14 12.2 0.2 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CoA_binding_2 PF13380.1 EEQ29183.1 - 0.18 11.9 0.6 0.77 9.9 0.4 1.9 1 1 0 1 1 1 0 CoA binding domain P21-Arc PF04062.9 EEQ29184.1 - 3.9e-79 264.4 0.0 4.6e-79 264.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Rep_fac_C PF08542.6 EEQ29185.1 - 5.4e-17 61.5 0.0 1.8e-16 59.8 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 EEQ29185.1 - 1.9e-16 60.4 0.3 4.3e-16 59.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EEQ29185.1 - 1.3e-13 50.9 0.0 3.6e-13 49.5 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EEQ29185.1 - 1.2e-11 44.0 0.0 9.8e-08 31.1 0.0 2.4 2 1 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EEQ29185.1 - 1.9e-07 31.3 0.4 2.2e-05 24.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 EEQ29185.1 - 2.5e-07 30.3 0.3 5.4e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EEQ29185.1 - 6.5e-07 29.5 0.1 0.00014 21.9 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 EEQ29185.1 - 1.6e-06 27.1 0.0 0.007 15.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EEQ29185.1 - 1.6e-06 27.7 0.0 4.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EEQ29185.1 - 2.5e-06 26.7 0.1 4.3e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 EEQ29185.1 - 1.3e-05 24.9 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ29185.1 - 1.4e-05 24.8 0.1 5.4e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EEQ29185.1 - 2.1e-05 24.2 0.1 5.3e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ29185.1 - 6e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EEQ29185.1 - 7.6e-05 21.7 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EEQ29185.1 - 0.00026 20.6 0.0 0.00071 19.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EEQ29185.1 - 0.00069 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EEQ29185.1 - 0.0021 17.3 0.1 0.53 9.4 0.0 2.3 1 1 1 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.21 EEQ29185.1 - 0.0024 17.3 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EEQ29185.1 - 0.0026 17.2 0.0 0.47 9.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.24 EEQ29185.1 - 0.0037 16.7 0.0 0.072 12.5 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EEQ29185.1 - 0.0062 15.5 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EEQ29185.1 - 0.0074 15.7 0.0 0.029 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEQ29185.1 - 0.0077 15.7 0.2 3.7 6.8 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain Arch_ATPase PF01637.13 EEQ29185.1 - 0.0085 15.8 0.0 0.015 15.0 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 EEQ29185.1 - 0.0086 16.3 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEQ29185.1 - 0.009 15.9 0.0 0.027 14.4 0.0 1.8 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 EEQ29185.1 - 0.021 14.6 0.0 0.41 10.4 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit MiaE PF06175.6 EEQ29185.1 - 0.029 13.7 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) TAFII28 PF04719.9 EEQ29185.1 - 0.03 14.1 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region IstB_IS21 PF01695.12 EEQ29185.1 - 0.03 13.7 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EEQ29185.1 - 0.031 15.0 0.0 0.063 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEQ29185.1 - 0.041 13.0 0.2 0.21 10.7 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEQ29185.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 EEQ29185.1 - 0.08 11.7 0.0 2.5 6.8 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain Peptidase_M19 PF01244.16 EEQ29186.1 - 2.6e-107 358.4 0.0 3e-107 358.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Synaptobrevin PF00957.16 EEQ29186.1 - 0.11 12.0 0.1 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Synaptobrevin His_Phos_2 PF00328.17 EEQ29187.1 - 3.6e-13 49.5 0.0 1.6e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.1 EEQ29187.1 - 0.043 13.5 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 PDGLE domain EST1 PF10374.4 EEQ29187.1 - 0.078 12.9 0.3 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 Telomerase activating protein Est1 Pkinase PF00069.20 EEQ29189.1 - 2.9e-12 46.2 0.0 4.2e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29189.1 - 3.7e-10 39.3 0.0 5.3e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EEQ29189.1 - 0.002 17.7 0.1 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pro_isomerase PF00160.16 EEQ29190.1 - 1.4e-38 132.4 0.0 3.7e-38 131.1 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD XAP5 PF04921.9 EEQ29190.1 - 0.18 11.3 4.5 0.42 10.1 3.1 1.7 1 0 0 1 1 1 0 XAP5, circadian clock regulator R3H PF01424.17 EEQ29191.1 - 3.3e-10 39.5 0.0 7.6e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EEQ29191.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ29191.1 - 1.8e-05 24.2 0.1 3.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ29191.1 - 0.026 14.3 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.18 EEQ29192.1 - 4e-11 43.1 0.0 1.1e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family HSF_DNA-bind PF00447.12 EEQ29193.1 - 8.9e-30 102.9 0.6 2e-29 101.7 0.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.17 EEQ29193.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Ets-domain DUF972 PF06156.8 EEQ29193.1 - 5.4 7.4 6.9 1.8 8.9 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Histone PF00125.19 EEQ29195.1 - 1.3e-17 63.7 0.4 4e-16 58.8 0.3 2.1 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pho88 PF10032.4 EEQ29196.1 - 2.4e-77 258.5 0.8 2.7e-77 258.3 0.6 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF2576 PF10845.3 EEQ29196.1 - 0.06 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) F-box-like PF12937.2 EEQ29197.1 - 2.3e-05 24.0 0.0 9.6e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like Gp_dh_C PF02800.15 EEQ29198.1 - 1.1e-73 245.9 0.0 1.5e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EEQ29198.1 - 1.7e-60 203.3 0.1 3.2e-60 202.4 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EEQ29198.1 - 0.00095 19.0 0.0 0.0049 16.7 0.0 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EEQ29198.1 - 0.01 16.3 0.1 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 EEQ29198.1 - 0.11 11.6 0.0 0.3 10.2 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hist_deacetyl PF00850.14 EEQ29199.1 - 9.7e-88 294.4 0.0 2.5e-87 293.0 0.0 1.7 1 1 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EEQ29199.1 - 4.8e-45 153.1 0.2 8e-45 152.4 0.1 1.4 1 0 0 1 1 1 1 Arb2 domain Sugar_tr PF00083.19 EEQ29200.1 - 2.9e-122 408.5 27.5 3.3e-122 408.3 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ29200.1 - 4.9e-22 78.1 37.9 3e-16 59.0 11.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ29200.1 - 0.0064 14.7 5.1 0.016 13.4 0.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.1 EEQ29200.1 - 0.17 12.2 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.11 EEQ29201.1 - 8e-30 103.7 40.1 8e-30 103.7 27.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.4 EEQ29201.1 - 0.96 7.9 6.5 7 5.0 0.3 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Peptidase_M16 PF00675.15 EEQ29202.1 - 5.4e-32 110.5 2.9 2.3e-21 76.0 0.3 3.7 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEQ29202.1 - 1.2e-29 103.2 0.2 2.3e-19 69.7 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain NUDIX_2 PF13869.1 EEQ29203.1 - 5.2e-82 273.7 0.0 6.1e-82 273.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4316 PF14195.1 EEQ29203.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) CoaE PF01121.15 EEQ29204.1 - 1.4e-42 145.1 0.0 1.9e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EEQ29204.1 - 0.00019 22.2 0.0 0.00053 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain 2TM PF13239.1 EEQ29204.1 - 0.078 13.0 0.2 0.078 13.0 0.2 1.8 2 0 0 2 2 2 0 2TM domain AAA_18 PF13238.1 EEQ29204.1 - 0.089 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain MPP6 PF10175.4 EEQ29205.1 - 0.032 14.6 0.1 2.3 8.6 0.1 3.0 3 0 0 3 3 3 0 M-phase phosphoprotein 6 OAD_gamma PF04277.8 EEQ29205.1 - 0.61 10.4 4.7 1.6 9.1 0.2 2.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain zf-CHCC PF10276.4 EEQ29206.1 - 7.7e-16 57.6 1.7 1.2e-15 56.9 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain ECH PF00378.15 EEQ29207.1 - 3.6e-46 157.2 0.0 4.5e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EEQ29207.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 GFA PF04828.9 EEQ29208.1 - 3.4e-08 33.3 1.7 9.8e-08 31.8 1.2 1.9 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme UPF0047 PF01894.12 EEQ29209.1 - 4.4e-42 142.6 0.0 5e-42 142.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Transcrip_act PF04949.8 EEQ29210.1 - 0.0026 17.3 0.1 0.0033 17.0 0.1 1.2 1 0 0 1 1 1 1 Transcriptional activator HEAT_2 PF13646.1 EEQ29210.1 - 0.029 14.6 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 HEAT repeats APH PF01636.18 EEQ29211.1 - 1.9e-19 70.3 0.0 2.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ29211.1 - 6.2e-05 22.6 0.0 8.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ29211.1 - 0.0002 20.6 0.0 0.16 11.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 EEQ29211.1 - 0.013 14.8 0.0 0.53 9.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.9 EEQ29211.1 - 0.036 13.0 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Pyr_redox_3 PF13738.1 EEQ29212.1 - 1.1e-20 74.6 0.0 3e-20 73.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ29212.1 - 1.1e-20 73.3 0.3 1.4e-18 66.4 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEQ29212.1 - 2.1e-07 30.1 0.0 7.1e-06 25.1 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEQ29212.1 - 0.0033 17.2 0.1 0.18 11.5 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEQ29212.1 - 0.0034 17.3 0.4 0.01 15.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ29212.1 - 0.015 15.2 0.0 0.47 10.2 0.0 2.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Exo_endo_phos PF03372.18 EEQ29213.1 - 2.9e-24 86.3 0.0 5.5e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EEQ29213.1 - 2.6 8.0 4.9 4.7 7.2 0.8 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat ERG4_ERG24 PF01222.12 EEQ29214.1 - 2.1e-146 487.8 9.0 2.4e-146 487.6 6.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EEQ29214.1 - 2.6e-05 23.6 0.1 7.9e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) UPF0197 PF05251.7 EEQ29214.1 - 0.043 14.1 1.8 0.18 12.0 1.3 2.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) zf-CHY PF05495.7 EEQ29215.1 - 1.9e-12 47.1 12.6 2.8e-12 46.5 8.8 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-3CxxC PF13695.1 EEQ29215.1 - 0.046 13.9 3.7 0.069 13.3 2.5 1.4 1 0 0 1 1 1 0 Zinc-binding domain zf-RING_3 PF14369.1 EEQ29215.1 - 0.14 12.1 1.1 0.14 12.1 0.7 2.4 2 0 0 2 2 2 0 zinc-finger Cytochrome_C7 PF14522.1 EEQ29215.1 - 1.1 8.9 12.6 1.8 8.2 8.6 1.5 1 1 0 1 1 1 0 Cytochrome c7 zinc_ribbon_5 PF13719.1 EEQ29215.1 - 2.2 7.9 12.6 2.6 7.7 0.1 3.2 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EEQ29215.1 - 3.6 7.3 13.8 2.6 7.8 0.1 3.2 3 1 0 3 3 3 0 zinc-ribbon domain Proteasome PF00227.21 EEQ29216.1 - 5.9e-54 182.2 0.1 7.4e-54 181.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEQ29216.1 - 1.2e-07 30.9 1.5 1.4e-07 30.6 0.0 2.0 2 1 0 2 2 2 1 Proteasome subunit A N-terminal signature Aldo_ket_red PF00248.16 EEQ29217.1 - 2.2e-61 207.1 0.0 2.7e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PH_2 PF08458.5 EEQ29217.1 - 0.12 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region APH PF01636.18 EEQ29218.1 - 1.3e-07 31.6 0.0 1.6e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ29219.1 - 6.1e-56 189.4 0.0 1.4e-47 162.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain FAD_binding_4 PF01565.18 EEQ29219.1 - 9.8e-37 125.5 0.2 2e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pkinase_Tyr PF07714.12 EEQ29219.1 - 2.2e-36 125.2 0.0 7e-32 110.5 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase FAD-oxidase_C PF02913.14 EEQ29219.1 - 2.4e-33 115.4 0.1 4.6e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Kinase-like PF14531.1 EEQ29219.1 - 5e-05 22.4 0.0 0.00012 21.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like ABC1 PF03109.11 EEQ29219.1 - 0.0035 17.2 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family CAP59_mtransfer PF11735.3 EEQ29222.1 - 9.9e-73 244.3 0.0 1.3e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF4048 PF13257.1 EEQ29223.1 - 2.9e-83 279.3 15.1 2.9e-83 279.3 10.4 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4048) DUF1626 PF07788.6 EEQ29223.1 - 0.12 12.1 0.6 0.23 11.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1626) TMEM247 PF15444.1 EEQ29223.1 - 0.13 12.0 1.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 247 Tim17 PF02466.14 EEQ29224.1 - 1.6e-50 170.4 6.3 2.3e-50 169.9 4.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 EEQ29224.1 - 0.013 15.1 5.3 0.97 9.1 2.1 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EEQ29224.1 - 0.019 14.6 4.9 0.019 14.6 3.4 2.6 3 0 0 3 3 3 0 Glycine zipper Bacteriocin_IIc PF10439.4 EEQ29224.1 - 6.5 6.9 17.9 17 5.6 8.9 2.8 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Oxidored_molyb PF00174.14 EEQ29225.1 - 1.4e-54 184.0 0.0 2e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EEQ29225.1 - 2.4e-28 98.3 0.4 5.7e-28 97.1 0.3 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain PALP PF00291.20 EEQ29226.1 - 1.7e-61 208.1 0.1 2.1e-61 207.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.2 EEQ29227.1 - 2.6e-95 318.8 0.0 1.2e-94 316.7 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EEQ29227.1 - 1.7e-10 41.0 3.5 6.8e-07 29.4 0.2 4.4 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.17 EEQ29227.1 - 1.1e-05 25.1 4.5 0.1 12.7 0.0 5.9 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EEQ29227.1 - 1.4e-05 25.4 5.4 0.018 15.5 0.2 5.1 5 1 0 5 5 5 2 HEAT-like repeat MMS19_N PF14500.1 EEQ29227.1 - 0.0077 15.5 0.1 0.045 13.0 0.0 2.3 2 1 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II zf-RanBP PF00641.13 EEQ29228.1 - 1.6e-19 68.6 8.4 5.9e-10 38.0 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.19 EEQ29228.1 - 1.8e-07 31.6 0.0 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.17 EEQ29228.1 - 2.6e-07 30.1 0.0 6.3e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ29228.1 - 4e-05 23.5 0.0 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HasA PF06438.7 EEQ29228.1 - 0.051 12.9 1.2 0.088 12.1 0.8 1.2 1 0 0 1 1 1 0 Heme-binding protein A (HasA) DZR PF12773.2 EEQ29228.1 - 3 7.7 9.5 0.82 9.5 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon Gtr1_RagA PF04670.7 EEQ29231.1 - 3.8e-91 304.3 0.1 4.6e-91 304.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EEQ29231.1 - 1.4e-07 31.0 0.0 2.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EEQ29231.1 - 1.6e-07 30.7 0.0 2.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEQ29231.1 - 4.2e-06 26.7 0.0 1.8e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ29231.1 - 6.7e-06 26.5 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 EEQ29231.1 - 0.0017 17.8 0.5 0.0053 16.2 0.2 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EEQ29231.1 - 0.0044 16.4 0.0 0.024 14.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.8 EEQ29231.1 - 0.012 14.5 0.1 0.021 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EEQ29231.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NikR_C PF08753.6 EEQ29231.1 - 0.053 13.4 0.1 6.9 6.6 0.0 2.6 2 0 0 2 2 2 0 NikR C terminal nickel binding domain DUF258 PF03193.11 EEQ29231.1 - 0.063 12.4 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEQ29231.1 - 0.12 11.7 0.2 0.34 10.3 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain AIG1 PF04548.11 EEQ29231.1 - 0.16 11.0 0.2 0.43 9.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family G-alpha PF00503.15 EEQ29231.1 - 0.58 8.7 3.4 1.8 7.1 1.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AA_permease PF00324.16 EEQ29232.1 - 2e-119 399.0 43.4 2.5e-119 398.7 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ29232.1 - 1.2e-33 116.3 45.9 1.5e-33 116.0 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease RdRP PF05183.7 EEQ29233.1 - 4.5e-118 395.4 0.0 1.2e-116 390.7 0.0 2.1 1 1 0 1 1 1 1 RNA dependent RNA polymerase Opi1 PF08618.5 EEQ29234.1 - 1.1e-94 317.8 1.2 3.2e-55 187.8 3.4 3.2 1 1 2 3 3 3 3 Transcription factor Opi1 LIP PF03583.9 EEQ29237.1 - 1.3e-74 251.0 0.0 1.9e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EEQ29237.1 - 0.0062 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LAT PF15234.1 EEQ29238.1 - 0.00064 19.2 0.2 0.00076 19.0 0.1 1.1 1 0 0 1 1 1 1 Linker for activation of T-cells Voldacs PF03517.8 EEQ29239.1 - 3.5e-32 111.0 1.1 3.5e-32 111.0 0.7 1.5 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Metallophos PF00149.23 EEQ29241.1 - 5.9e-41 140.0 1.1 1e-40 139.3 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3199 PF11436.3 EEQ29242.1 - 0.014 15.2 0.1 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) Abhydrolase_2 PF02230.11 EEQ29243.1 - 1.7e-17 63.6 0.0 2.2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEQ29243.1 - 8e-08 32.4 0.3 9.9e-08 32.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ29243.1 - 0.00039 20.1 0.0 0.0006 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EEQ29244.1 - 0.00013 21.8 3.4 0.00021 21.1 2.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEQ29244.1 - 0.00054 18.6 0.6 0.00079 18.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.18 EEQ29245.1 - 0.00072 19.3 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ29245.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Abhydrolase_5 PF12695.2 EEQ29246.1 - 6.6e-13 48.6 0.0 2.1e-11 43.7 0.0 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ29246.1 - 5.6e-11 42.7 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EEQ29246.1 - 2.5e-05 23.0 0.0 8.1e-05 21.3 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 EEQ29246.1 - 4e-05 23.0 0.0 0.0098 15.1 0.0 2.5 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EEQ29246.1 - 0.00053 19.2 0.0 0.0015 17.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EEQ29246.1 - 0.0016 18.0 0.7 0.21 11.0 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EEQ29246.1 - 0.0018 18.0 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.9 EEQ29246.1 - 0.0051 16.0 0.2 3 6.9 0.0 2.6 1 1 1 2 2 2 2 Secretory lipase AXE1 PF05448.7 EEQ29246.1 - 0.047 12.1 0.0 0.13 10.7 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) CorA PF01544.13 EEQ29247.1 - 9.8e-11 41.2 0.1 2.6e-10 39.8 0.1 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein 2HCT PF03390.10 EEQ29247.1 - 0.057 11.7 0.1 0.26 9.6 0.1 1.8 2 0 0 2 2 2 0 2-hydroxycarboxylate transporter family TPR_12 PF13424.1 EEQ29248.1 - 9.3e-14 51.1 11.1 4.2e-09 36.2 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 EEQ29248.1 - 1e-06 27.8 0.0 1.1e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TPR_11 PF13414.1 EEQ29248.1 - 7e-05 22.3 1.8 0.053 13.1 0.0 4.0 4 0 0 4 4 4 1 TPR repeat PGAP1 PF07819.8 EEQ29248.1 - 0.00014 21.5 0.0 0.00048 19.7 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EEQ29248.1 - 0.0013 18.7 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_2 PF07719.12 EEQ29248.1 - 0.0013 18.4 4.4 16 5.6 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Cutinase PF01083.17 EEQ29248.1 - 0.0058 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Cutinase TPR_1 PF00515.23 EEQ29248.1 - 0.012 15.2 0.2 24 4.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ29248.1 - 0.012 16.2 2.4 0.84 10.3 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ29248.1 - 0.018 14.7 0.3 6.3 6.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF676 PF05057.9 EEQ29248.1 - 0.028 13.7 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_22 PF13401.1 EEQ29248.1 - 0.031 14.4 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain TPR_14 PF13428.1 EEQ29248.1 - 0.064 13.9 0.2 1.7 9.5 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ29248.1 - 2.1 8.3 11.9 9.6 6.2 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat HAD_2 PF13419.1 EEQ29249.1 - 6.5e-10 39.5 0.0 1.8e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ29249.1 - 4.6e-08 32.6 0.0 8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEQ29249.1 - 4.6e-08 33.7 0.0 1.2e-06 29.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase EXS PF03124.9 EEQ29250.1 - 2.4e-66 224.1 18.0 4.1e-57 193.7 8.4 2.1 1 1 1 2 2 2 2 EXS family SPX PF03105.14 EEQ29250.1 - 3.9e-48 164.6 10.1 2.8e-40 138.8 0.0 2.9 3 0 0 3 3 3 2 SPX domain PBP1_TM PF14812.1 EEQ29250.1 - 5.9 7.2 7.9 18 5.7 5.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Astro_capsid PF03115.9 EEQ29250.1 - 9 4.4 6.1 0.71 8.0 0.9 1.5 2 0 0 2 2 2 0 Astrovirus capsid protein precursor Peptidase_S8 PF00082.17 EEQ29251.1 - 1.4e-53 181.8 9.3 2.2e-53 181.2 6.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ29251.1 - 2.3e-20 72.9 0.2 5.4e-20 71.7 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 HNH_2 PF13391.1 EEQ29252.1 - 0.00021 21.0 0.0 0.00045 19.9 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Mito_carr PF00153.22 EEQ29253.1 - 1.1e-33 114.7 10.2 3.7e-15 55.4 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Beach PF02138.13 EEQ29254.1 - 3.3e-108 361.2 0.0 5.6e-108 360.4 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EEQ29254.1 - 2.1e-11 43.5 1.5 8e-11 41.7 0.0 2.5 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EEQ29254.1 - 3.5e-11 42.5 2.1 4e-05 23.3 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EEQ29254.1 - 4.8e-07 30.1 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TerB-C PF15615.1 EEQ29254.1 - 0.088 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 TerB-C domain LysM PF01476.15 EEQ29255.1 - 4e-12 45.8 0.7 3.7e-05 23.5 0.2 2.3 2 0 0 2 2 2 2 LysM domain UPF0203 PF05254.7 EEQ29255.1 - 0.045 13.5 0.4 7.5 6.4 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) LRRNT_2 PF08263.7 EEQ29255.1 - 0.075 13.0 3.8 0.64 10.0 0.4 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain APH PF01636.18 EEQ29256.1 - 9.2e-12 45.1 0.0 2.5e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Transaldolase PF00923.14 EEQ29257.1 - 1.3e-94 316.6 0.1 1.4e-94 316.4 0.1 1.0 1 0 0 1 1 1 1 Transaldolase Sod_Cu PF00080.15 EEQ29258.1 - 3.4e-45 153.6 5.8 4e-45 153.4 4.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Fungal_trans PF04082.13 EEQ29259.1 - 9.9e-16 57.3 0.4 1.9e-15 56.4 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ29259.1 - 8.3e-06 25.6 8.4 1.9e-05 24.4 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNase PF00565.12 EEQ29261.1 - 1.7e-79 263.1 0.6 8.2e-26 90.3 0.0 5.6 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EEQ29261.1 - 1.4e-24 86.2 0.0 6e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EEQ29261.1 - 5.2e-05 22.4 0.0 9.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF3297 PF11730.3 EEQ29261.1 - 0.031 13.9 0.0 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) CRAL_TRIO PF00650.15 EEQ29262.1 - 4.7e-25 87.9 0.0 6.4e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEQ29262.1 - 9e-09 35.3 0.0 2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AT_hook PF02178.14 EEQ29263.1 - 0.11 12.2 85.1 0.052 13.2 1.9 7.1 8 0 0 8 8 8 0 AT hook motif DUF1620 PF07774.8 EEQ29264.1 - 1.5e-73 246.6 0.0 8.1e-73 244.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EEQ29264.1 - 4e-16 59.2 10.6 1.2e-14 54.4 0.5 2.9 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EEQ29264.1 - 1.2e-06 27.7 0.7 0.22 11.1 0.0 4.4 4 0 0 4 4 4 3 PQQ enzyme repeat adh_short PF00106.20 EEQ29265.1 - 1.4e-19 70.6 0.1 7.9e-19 68.1 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ29265.1 - 1.2e-08 34.8 0.0 5.7e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EEQ29265.1 - 2.4e-06 27.5 0.0 7e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Aa_trans PF01490.13 EEQ29266.1 - 4.7e-93 311.8 18.5 7.1e-93 311.3 12.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.5 EEQ29266.1 - 0.019 12.9 5.1 0.035 12.1 3.5 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO HEV_ORF1 PF02444.11 EEQ29266.1 - 2.9 8.1 6.7 5 7.3 0.2 3.5 2 1 1 3 3 3 0 Hepatitis E virus ORF-2 (Putative capsid protein) Bax1-I PF01027.15 EEQ29267.1 - 6e-53 179.5 28.8 7e-53 179.2 20.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.2 EEQ29267.1 - 0.00074 18.7 12.4 0.0011 18.1 8.6 1.4 1 1 0 1 1 1 1 Bax inhibitor 1 like Lysis_S PF04971.7 EEQ29267.1 - 0.12 12.0 1.8 0.44 10.2 1.3 2.0 1 0 0 1 1 1 0 Lysis protein S Spore_YhaL PF14147.1 EEQ29267.1 - 0.14 11.5 0.1 0.52 9.7 0.1 2.0 1 0 0 1 1 1 0 Sporulation protein YhaL 7TMR-DISM_7TM PF07695.6 EEQ29267.1 - 0.28 10.8 26.9 1.4 8.5 3.2 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Myc_target_1 PF15179.1 EEQ29267.1 - 0.3 10.6 0.1 0.3 10.6 0.1 1.7 2 0 0 2 2 2 0 Myc target protein 1 Orbi_NS3 PF01616.11 EEQ29267.1 - 0.38 9.7 2.0 1.2 8.0 0.3 2.1 2 0 0 2 2 2 0 Orbivirus NS3 UQ_con PF00179.21 EEQ29268.1 - 3.8e-40 136.5 0.0 4.8e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ29268.1 - 0.0038 16.9 0.0 0.017 14.9 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ29268.1 - 0.0057 16.5 0.3 0.016 15.0 0.2 1.8 1 1 1 2 2 2 1 RWD domain Peptidase_M36 PF02128.10 EEQ29269.1 - 1.7e-150 501.0 0.9 2.2e-150 500.6 0.7 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EEQ29269.1 - 1.5e-12 46.7 3.9 2.3e-12 46.1 1.7 2.1 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EEQ29269.1 - 0.086 12.5 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain ABC_tran PF00005.22 EEQ29270.1 - 4.5e-56 188.9 0.2 6.2e-31 107.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ29270.1 - 1.4e-45 155.8 29.1 1.7e-25 90.0 9.6 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_25 PF13481.1 EEQ29270.1 - 2.7e-08 33.4 0.1 0.0079 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EEQ29270.1 - 1.2e-07 32.3 0.7 0.00014 22.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EEQ29270.1 - 2.3e-07 31.0 7.8 0.037 13.9 0.0 4.3 4 1 0 5 5 5 2 AAA domain SMC_N PF02463.14 EEQ29270.1 - 4.2e-07 29.4 8.1 0.015 14.5 1.3 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EEQ29270.1 - 3.2e-06 26.7 0.6 0.25 10.7 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain AAA_29 PF13555.1 EEQ29270.1 - 4.6e-05 22.8 0.4 0.33 10.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEQ29270.1 - 5.9e-05 23.0 0.2 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EEQ29270.1 - 6.2e-05 22.2 0.4 0.18 10.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ29270.1 - 9.1e-05 22.5 0.9 0.33 10.8 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain DUF87 PF01935.12 EEQ29270.1 - 0.00022 21.1 0.4 0.013 15.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EEQ29270.1 - 0.00041 19.5 0.9 0.11 11.5 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 EEQ29270.1 - 0.00053 18.9 0.2 0.016 14.1 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 EEQ29270.1 - 0.001 19.1 0.9 5.2 7.2 0.0 3.6 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EEQ29270.1 - 0.0011 18.5 0.1 0.61 9.5 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EEQ29270.1 - 0.0015 18.9 0.5 2.8 8.4 0.1 2.8 2 1 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EEQ29270.1 - 0.0017 19.1 0.0 3.7 8.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEQ29270.1 - 0.0023 18.2 0.1 2.5 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEQ29270.1 - 0.008 15.8 0.2 8.3 6.1 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EEQ29270.1 - 0.011 15.1 1.1 2.6 7.4 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.24 EEQ29270.1 - 0.013 15.7 0.3 2.5 8.2 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EEQ29270.1 - 0.04 13.7 0.4 3.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 EEQ29270.1 - 0.061 12.9 0.4 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EEQ29270.1 - 0.14 12.0 0.0 11 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEQ29270.1 - 0.16 11.5 0.1 10 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EEQ29270.1 - 0.24 9.9 1.1 8.5 4.8 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain UPF0079 PF02367.12 EEQ29270.1 - 0.33 10.5 1.7 10 5.7 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 EEQ29270.1 - 0.38 9.7 0.0 0.81 8.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 EEQ29270.1 - 0.41 9.5 0.9 15 4.4 0.0 2.5 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EEQ29270.1 - 0.99 8.8 2.9 1.9 7.8 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_12 PF13087.1 EEQ29271.1 - 3.3e-35 121.2 0.0 6.3e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ29271.1 - 1.7e-23 83.4 0.0 5.7e-23 81.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ29271.1 - 2e-09 37.0 0.0 5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ29271.1 - 9.7e-09 35.0 0.0 8.3e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EEQ29271.1 - 2.3e-05 24.0 0.0 0.0047 16.4 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EEQ29271.1 - 0.0025 16.8 0.0 0.15 10.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EEQ29271.1 - 0.0031 16.7 0.0 0.0069 15.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.10 EEQ29271.1 - 0.008 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ29271.1 - 0.036 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase WD40 PF00400.27 EEQ29272.1 - 5.2e-21 73.6 6.6 0.00094 18.9 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat Helitron_like_N PF14214.1 EEQ29272.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Trypan_PARP PF05887.6 EEQ29272.1 - 1.8 8.3 12.4 0.12 12.1 2.5 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PRP38 PF03371.10 EEQ29274.1 - 6.3e-53 178.9 0.0 8.1e-53 178.5 0.0 1.1 1 0 0 1 1 1 1 PRP38 family DUF848 PF05852.6 EEQ29274.1 - 0.1 12.4 1.0 0.16 11.8 0.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Transp_cyt_pur PF02133.10 EEQ29277.1 - 3.3e-29 101.7 22.9 3.3e-29 101.7 15.9 1.8 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.20 EEQ29278.1 - 2.8e-18 66.3 0.3 5e-18 65.5 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ29278.1 - 8.3e-10 38.6 0.1 1.4e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEQ29278.1 - 0.0045 15.9 0.0 0.006 15.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EEQ29278.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF473 PF04322.7 EEQ29278.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF473) WSC PF01822.14 EEQ29279.1 - 2.6e-10 40.0 9.6 2.6e-10 40.0 6.7 2.8 2 1 0 2 2 2 1 WSC domain MIP-T3 PF10243.4 EEQ29279.1 - 0.0028 16.2 3.7 0.0032 16.0 2.6 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF2668 PF10873.3 EEQ29279.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2668) MFS_1 PF07690.11 EEQ29282.1 - 2.1e-36 125.3 67.7 5.1e-27 94.5 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEQ29282.1 - 6.4e-10 37.9 13.0 6.4e-10 37.9 9.0 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EEQ29282.1 - 0.00017 20.3 11.2 0.00017 20.3 7.8 3.2 2 2 1 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.13 EEQ29283.1 - 1.5e-18 66.6 0.1 2.5e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ29283.1 - 2.8e-11 43.1 12.4 7.4e-11 41.7 8.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IMS PF00817.15 EEQ29285.1 - 6.8e-38 129.7 0.0 8.3e-37 126.2 0.0 2.3 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EEQ29285.1 - 1.3e-11 44.4 0.0 2.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain ABC1 PF03109.11 EEQ29286.1 - 4.7e-21 74.9 0.1 1.3e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EEQ29286.1 - 0.0045 16.7 0.2 0.034 13.8 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family SAM_2 PF07647.12 EEQ29287.1 - 6e-11 42.0 0.1 1.1e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EEQ29287.1 - 1.1e-07 31.9 0.2 2.7e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EEQ29287.1 - 2.9e-05 24.2 0.1 6.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 PH domain Ste50p-SAM PF09235.5 EEQ29287.1 - 0.0016 18.3 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.11 EEQ29287.1 - 0.0088 15.7 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PH_6 PF15406.1 EEQ29287.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Fungal_trans_2 PF11951.3 EEQ29289.1 - 1.4e-83 280.6 0.1 1.9e-83 280.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ29289.1 - 1.2e-06 28.3 8.8 2.3e-06 27.3 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EEQ29290.1 - 9.6e-26 88.6 12.8 1.8e-07 30.7 0.1 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat UAF_Rrn10 PF05234.6 EEQ29291.1 - 0.00028 20.9 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Mnd1 PF03962.10 EEQ29292.1 - 1.4e-43 148.7 10.0 3e-43 147.6 6.9 1.4 1 1 0 1 1 1 1 Mnd1 family HTH_20 PF12840.2 EEQ29292.1 - 0.0021 17.8 0.1 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain TBPIP PF07106.8 EEQ29292.1 - 0.033 13.7 6.3 0.027 13.9 3.3 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EEQ29292.1 - 0.037 11.8 1.8 0.037 11.8 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EEQ29292.1 - 0.099 11.0 6.4 0.11 10.8 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EEQ29292.1 - 0.41 10.1 18.3 0.11 12.0 3.3 3.4 2 1 2 4 4 4 0 Septum formation initiator SpoVR PF04293.8 EEQ29292.1 - 0.54 8.5 5.5 0.8 7.9 3.8 1.2 1 0 0 1 1 1 0 SpoVR like protein SlyX PF04102.7 EEQ29292.1 - 0.82 10.0 8.6 0.44 10.9 2.6 2.7 2 0 0 2 2 2 0 SlyX DUF1192 PF06698.6 EEQ29292.1 - 1 9.2 9.2 2.5 7.9 2.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Fib_alpha PF08702.5 EEQ29292.1 - 1.4 9.0 9.8 0.57 10.2 4.4 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EEQ29292.1 - 2.1 7.3 13.4 3.2 6.6 9.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EEQ29292.1 - 6.1 6.3 14.3 7.3 6.1 9.6 1.4 1 1 0 1 1 1 0 IncA protein DHO_dh PF01180.16 EEQ29293.1 - 2.3e-63 213.9 0.6 5.2e-55 186.4 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EEQ29293.1 - 0.00024 20.4 0.2 0.33 10.1 0.0 2.4 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 EEQ29293.1 - 0.011 14.5 1.7 0.044 12.6 1.2 2.0 1 1 0 1 1 1 0 FMN-dependent dehydrogenase IMPDH PF00478.20 EEQ29293.1 - 0.058 12.2 0.4 0.55 9.0 0.1 2.4 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain APH PF01636.18 EEQ29294.1 - 3.3e-20 72.8 0.0 1.5e-19 70.7 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ29294.1 - 0.0046 15.6 0.0 0.053 12.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEQ29294.1 - 0.053 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase LacAB_rpiB PF02502.13 EEQ29295.1 - 4.8e-42 142.9 0.2 5.6e-42 142.7 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.3 EEQ29295.1 - 0.023 14.7 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2620 TIM PF00121.13 EEQ29296.1 - 2.4e-43 147.9 0.0 7.4e-43 146.3 0.0 1.7 1 1 0 1 1 1 1 Triosephosphate isomerase Pkinase PF00069.20 EEQ29298.1 - 1.6e-11 43.8 0.0 4.1e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29298.1 - 1.4e-09 37.4 0.0 2.7e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EEQ29298.1 - 3.4e-05 23.5 0.0 8.7e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EEQ29298.1 - 7.8e-05 22.5 0.2 0.00075 19.2 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF4303 PF14136.1 EEQ29299.1 - 0.14 11.7 0.2 0.25 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) U-box PF04564.10 EEQ29300.1 - 1.6e-23 82.4 0.8 9e-23 80.0 0.1 2.2 2 0 0 2 2 2 1 U-box domain TPR_11 PF13414.1 EEQ29300.1 - 1.9e-15 56.2 5.8 1.9e-15 56.2 0.5 2.4 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 EEQ29300.1 - 1.3e-07 30.9 7.4 0.00016 21.3 0.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ29300.1 - 1.5e-07 31.8 5.8 5.2e-05 23.7 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ29300.1 - 8.6e-06 25.1 5.9 7.7e-05 22.1 1.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ29300.1 - 1.2e-05 25.5 1.0 0.00026 21.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ29300.1 - 0.00074 19.9 2.2 0.18 12.4 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat zf-Nse PF11789.3 EEQ29300.1 - 0.0021 17.5 0.1 0.011 15.2 0.0 2.0 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TPR_17 PF13431.1 EEQ29300.1 - 0.0041 17.2 3.6 0.015 15.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ29300.1 - 0.005 16.7 4.2 0.38 10.7 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EEQ29300.1 - 0.041 14.0 0.3 0.086 12.9 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Spore_GerAC PF05504.6 EEQ29300.1 - 0.06 13.1 0.3 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal zf-RING_UBOX PF13445.1 EEQ29300.1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger ACBP PF00887.14 EEQ29301.1 - 8.6e-23 79.8 0.2 9.7e-23 79.6 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.7 EEQ29302.1 - 7.7e-149 496.0 0.0 9e-149 495.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EEQ29302.1 - 0.0024 17.6 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain Glyco_hydro_18 PF00704.23 EEQ29303.1 - 0.00063 19.3 0.0 0.0013 18.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEQ29303.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 LysM domain F-box PF00646.28 EEQ29305.1 - 0.076 12.6 0.5 0.22 11.2 0.4 1.8 1 0 0 1 1 1 0 F-box domain Aldolase PF01081.14 EEQ29305.1 - 0.087 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase AA_permease_2 PF13520.1 EEQ29306.1 - 5.4e-57 193.2 51.7 6.6e-57 192.9 35.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ29306.1 - 9.9e-15 53.8 41.8 1.4e-14 53.2 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease ABC_tran PF00005.22 EEQ29307.1 - 2.5e-47 160.6 0.8 4.3e-27 95.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EEQ29307.1 - 3.8e-47 161.0 24.6 4.7e-20 72.1 0.6 4.1 3 1 1 4 4 4 4 ABC transporter transmembrane region AAA_21 PF13304.1 EEQ29307.1 - 2.8e-09 37.3 0.2 0.01 15.8 0.0 4.4 4 1 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 EEQ29307.1 - 3.9e-06 26.8 0.1 0.055 13.4 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EEQ29307.1 - 1e-05 26.0 0.9 0.22 12.0 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EEQ29307.1 - 1e-05 25.5 0.9 0.06 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EEQ29307.1 - 3e-05 24.8 0.0 0.47 11.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ29307.1 - 6.7e-05 22.3 0.6 0.16 11.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ArgK PF03308.11 EEQ29307.1 - 0.00016 20.5 1.6 0.19 10.4 0.1 2.4 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 EEQ29307.1 - 0.00055 19.4 0.8 1.4 8.2 0.2 3.3 3 0 0 3 3 3 2 AAA-like domain SMC_N PF02463.14 EEQ29307.1 - 0.00058 19.1 11.6 0.011 14.9 1.1 4.4 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EEQ29307.1 - 0.00069 18.8 0.4 0.51 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEQ29307.1 - 0.00075 19.8 3.0 0.37 11.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 EEQ29307.1 - 0.0021 17.9 2.2 0.23 11.2 0.1 2.8 3 0 0 3 3 2 1 Dynamin family Zeta_toxin PF06414.7 EEQ29307.1 - 0.0047 16.0 0.1 2.2 7.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 EEQ29307.1 - 0.0059 16.4 1.2 0.099 12.4 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 EEQ29307.1 - 0.0067 15.8 0.1 1.5 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEQ29307.1 - 0.0071 16.6 0.0 5.1 7.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEQ29307.1 - 0.012 15.8 0.6 5.5 7.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 EEQ29307.1 - 0.072 12.1 0.0 12 4.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EEQ29307.1 - 0.11 12.5 3.4 0.22 11.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 EEQ29307.1 - 0.12 11.8 0.0 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EEQ29307.1 - 0.64 9.5 6.3 2.2 7.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain Terpene_synth_C PF03936.11 EEQ29308.1 - 6.5e-17 61.6 0.0 8e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Aminotran_3 PF00202.16 EEQ29310.1 - 2.1e-102 342.4 0.0 2.5e-102 342.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EEQ29310.1 - 0.0042 16.2 0.0 0.0094 15.1 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_22 PF03901.12 EEQ29311.1 - 3.2e-73 247.1 15.3 1.2e-41 143.1 4.3 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family ArfGap PF01412.13 EEQ29312.1 - 1.4e-37 128.0 0.0 3.1e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Radial_spoke_3 PF06098.6 EEQ29313.1 - 2.7 6.9 16.5 0.57 9.1 9.4 1.4 1 1 0 1 1 1 0 Radial spoke protein 3 PHD PF00628.24 EEQ29314.1 - 1.6e-06 27.6 9.6 4e-06 26.4 6.7 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EEQ29314.1 - 5.2e-06 26.8 0.1 5.2e-06 26.8 0.1 2.9 3 2 0 3 3 3 1 SET domain PHD_2 PF13831.1 EEQ29314.1 - 0.29 10.5 5.7 0.58 9.5 4.0 1.5 1 0 0 1 1 1 0 PHD-finger ORC4_C PF14629.1 EEQ29315.1 - 1.6e-52 177.9 0.0 2.8e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EEQ29315.1 - 3.7e-17 62.9 2.0 3.9e-16 59.5 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ29315.1 - 2e-06 27.9 0.1 1.4e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEQ29315.1 - 0.00014 22.0 0.2 0.00095 19.3 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EEQ29315.1 - 0.00018 20.5 0.0 0.00034 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EEQ29315.1 - 0.0022 17.0 0.0 0.0052 15.8 0.0 1.6 1 0 0 1 1 1 1 KAP family P-loop domain Arch_ATPase PF01637.13 EEQ29315.1 - 0.0028 17.3 1.1 0.017 14.8 0.0 2.5 2 2 0 2 2 2 1 Archaeal ATPase AAA_29 PF13555.1 EEQ29315.1 - 0.0042 16.5 0.3 0.014 14.9 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EEQ29315.1 - 0.0084 15.7 0.2 0.043 13.4 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EEQ29315.1 - 0.05 13.5 0.1 0.89 9.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain Med3 PF11593.3 EEQ29315.1 - 0.55 9.4 13.1 1.2 8.3 9.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Red1 PF07964.6 EEQ29315.1 - 1.8 6.6 13.2 2.6 6.0 9.1 1.1 1 0 0 1 1 1 0 Rec10 / Red1 RGS PF00615.14 EEQ29316.1 - 5.4e-29 100.7 0.0 1.5e-28 99.2 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EEQ29316.1 - 5.5e-25 86.9 0.1 6.1e-18 64.3 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF480 PF04337.7 EEQ29316.1 - 0.098 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF480 CDC73 PF05179.9 EEQ29317.1 - 2.8e-39 135.1 0.2 2.6e-38 131.9 0.1 2.3 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family 4HBT PF03061.17 EEQ29318.1 - 3.5e-13 49.4 0.0 5.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EEQ29318.1 - 7.1e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily NOT2_3_5 PF04153.13 EEQ29319.1 - 3.1e-33 114.5 0.1 3.1e-33 114.5 0.1 2.3 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.8 EEQ29320.1 - 3e-19 68.7 0.2 4.7e-19 68.0 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.13 EEQ29321.1 - 6.1e-170 565.2 0.0 7.8e-170 564.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SMC_N PF02463.14 EEQ29322.1 - 4.2e-70 235.4 0.0 1.3e-69 233.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEQ29322.1 - 1.8e-22 79.5 1.0 3e-21 75.6 0.2 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EEQ29322.1 - 1.2e-12 48.5 5.7 1.2e-12 48.5 4.0 6.4 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EEQ29322.1 - 2.5e-11 44.0 13.6 1.5e-05 25.1 0.1 4.0 4 0 0 4 4 4 2 AAA domain MscS_porin PF12795.2 EEQ29322.1 - 0.00031 20.1 16.7 0.00031 20.1 11.6 6.2 4 2 2 6 6 6 1 Mechanosensitive ion channel porin domain AAA_29 PF13555.1 EEQ29322.1 - 0.00088 18.7 0.1 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EEQ29322.1 - 0.85 8.7 33.8 0.33 10.0 3.0 5.6 3 2 4 7 7 7 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EEQ29322.1 - 3.8 7.8 26.2 1.6 8.9 0.0 5.6 3 2 0 3 3 3 0 ABC transporter CUE PF02845.11 EEQ29323.1 - 1.7e-10 40.2 0.0 2.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain Sld5 PF05916.6 EEQ29324.1 - 4.6e-26 91.2 0.0 1.4e-25 89.6 0.0 1.7 1 1 0 1 1 1 1 GINS complex protein DIE2_ALG10 PF04922.7 EEQ29325.1 - 1.9e-72 244.4 13.3 1.7e-71 241.2 9.2 2.5 1 1 0 1 1 1 1 DIE2/ALG10 family FimP PF09766.4 EEQ29326.1 - 4.3e-23 81.9 8.9 6e-23 81.4 6.2 1.2 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 EEQ29326.1 - 0.00043 20.2 15.4 0.039 13.8 1.6 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) K-box PF01486.12 EEQ29326.1 - 0.015 15.0 0.7 0.015 15.0 0.5 3.0 2 2 1 3 3 3 0 K-box region DUF948 PF06103.6 EEQ29326.1 - 0.11 12.3 3.5 10 6.0 0.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Bestrophin PF01062.16 EEQ29326.1 - 0.17 10.8 0.1 0.17 10.8 0.1 1.5 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Pinin_SDK_memA PF04696.8 EEQ29326.1 - 0.27 10.8 7.1 0.3 10.6 1.8 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region HAUS-augmin3 PF14932.1 EEQ29326.1 - 0.29 10.2 14.9 0.041 13.0 1.7 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Mnd1 PF03962.10 EEQ29326.1 - 0.87 9.2 9.5 4.4 6.9 2.7 2.1 2 0 0 2 2 2 0 Mnd1 family DUF972 PF06156.8 EEQ29326.1 - 1.2 9.5 10.2 1.5 9.2 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF349 PF03993.7 EEQ29326.1 - 1.5 9.0 10.2 0.23 11.6 3.7 2.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) V-SNARE PF05008.10 EEQ29326.1 - 1.8 8.8 12.8 6.4 7.0 0.5 3.4 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DivIC PF04977.10 EEQ29326.1 - 2.6 7.6 13.1 0.42 10.1 0.2 2.7 2 1 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EEQ29326.1 - 2.6 8.4 11.0 12 6.3 3.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) BBS2_C PF14782.1 EEQ29326.1 - 2.9 6.3 10.0 5.4 5.4 0.2 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal FUSC PF04632.7 EEQ29326.1 - 3.9 5.7 5.1 4.6 5.5 3.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family p450 PF00067.17 EEQ29327.1 - 3.2e-47 161.1 0.0 4.2e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HlyIII PF03006.15 EEQ29328.1 - 1.2e-58 198.1 23.1 1.4e-58 197.8 16.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related GlnD_UR_UTase PF08335.6 EEQ29328.1 - 0.19 11.5 5.5 0.32 10.8 0.4 2.2 1 1 1 2 2 2 0 GlnD PII-uridylyltransferase Planc_extracel PF07595.7 EEQ29328.1 - 1.2 8.9 9.3 3.8 7.3 0.2 2.8 2 0 0 2 2 2 0 Planctomycete extracellular Sugar_tr PF00083.19 EEQ29329.1 - 1.1e-118 396.6 22.4 2e-118 395.8 15.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ29329.1 - 2.1e-24 85.9 44.8 4.4e-15 55.2 11.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3915 PF13054.1 EEQ29329.1 - 0.3 11.0 0.8 0.66 9.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Methyltransf_11 PF08241.7 EEQ29330.1 - 2.4e-14 53.5 0.0 5.3e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ29330.1 - 2.8e-14 53.3 0.0 1.3e-13 51.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ29330.1 - 2.1e-10 40.5 0.0 3.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ29330.1 - 6.9e-09 35.7 0.1 2.3e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ29330.1 - 1.1e-08 35.5 0.0 3.3e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ29330.1 - 1.3e-08 35.0 0.0 2.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ29330.1 - 4.6e-08 32.7 0.0 7.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EEQ29330.1 - 8.2e-06 25.1 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 EEQ29330.1 - 1.2e-05 24.5 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EEQ29330.1 - 5e-05 22.7 0.0 7.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 EEQ29330.1 - 0.0002 20.4 0.0 0.092 11.6 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family FmrO PF07091.6 EEQ29330.1 - 0.0062 15.5 0.0 0.0094 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 EEQ29330.1 - 0.0065 15.5 0.1 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EEQ29330.1 - 0.0078 15.8 0.0 0.021 14.4 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase DUF3419 PF11899.3 EEQ29330.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 EEQ29330.1 - 0.031 15.1 0.0 0.073 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.5 EEQ29330.1 - 0.052 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_16 PF10294.4 EEQ29330.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.6 EEQ29330.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) GMC_oxred_N PF00732.14 EEQ29331.1 - 9.5e-51 172.6 0.0 1.2e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ29331.1 - 3e-35 121.6 0.0 4.6e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EEQ29331.1 - 0.0047 15.8 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEQ29331.1 - 0.023 14.7 0.1 0.066 13.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ29331.1 - 0.026 13.4 0.1 0.11 11.3 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ29331.1 - 0.05 12.4 1.5 0.5 9.1 0.6 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 EEQ29331.1 - 0.13 12.3 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEQ29331.1 - 0.14 10.7 0.3 0.2 10.2 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Catalase PF00199.14 EEQ29332.1 - 5.2e-173 575.1 0.4 6.2e-173 574.8 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEQ29332.1 - 2.5e-05 24.0 0.0 6.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive TFIIA PF03153.8 EEQ29334.1 - 0.0018 18.2 0.9 0.0028 17.6 0.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Diphthamide_syn PF01866.12 EEQ29335.1 - 2.8e-42 145.0 0.0 8.8e-42 143.3 0.0 1.8 2 1 0 2 2 2 1 Putative diphthamide synthesis protein Fe-ADH PF00465.14 EEQ29337.1 - 1.6e-73 247.4 1.3 1.8e-73 247.3 0.9 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEQ29337.1 - 2.9e-15 56.2 0.1 4.1e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PQQ_2 PF13360.1 EEQ29338.1 - 0.00016 21.1 0.4 0.015 14.7 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain WD40 PF00400.27 EEQ29338.1 - 0.0026 17.5 4.5 0.29 11.1 0.0 4.3 4 1 0 4 4 4 1 WD domain, G-beta repeat TLP-20 PF06088.6 EEQ29338.1 - 0.0056 16.3 0.8 0.0088 15.7 0.6 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nucleoplasmin PF03066.10 EEQ29338.1 - 0.015 14.8 1.0 0.026 14.0 0.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin U79_P34 PF03064.11 EEQ29338.1 - 0.16 11.4 7.2 0.25 10.8 5.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.9 EEQ29338.1 - 0.17 9.8 2.9 0.23 9.4 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PIG-S PF10510.4 EEQ29339.1 - 1.3e-173 578.4 3.2 1.6e-173 578.1 2.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Lustrin_cystein PF14625.1 EEQ29340.1 - 2.1 8.4 17.2 0.15 12.1 4.0 2.8 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Haemadin PF09065.5 EEQ29340.1 - 2.2 7.9 9.6 1.6 8.3 4.0 2.7 2 0 0 2 2 2 0 Haemadin Sod_Fe_C PF02777.13 EEQ29341.1 - 3.2e-09 36.5 0.0 1.3e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Polyketide_cyc PF03364.15 EEQ29342.1 - 1.1e-19 70.6 0.0 2e-19 69.8 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport RdRP_2 PF00978.16 EEQ29342.1 - 0.035 12.8 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase JmjC PF02373.17 EEQ29344.1 - 4.2e-09 36.6 0.0 9.9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ZZ PF00569.12 EEQ29344.1 - 1.5e-05 24.3 8.7 1.5e-05 24.3 6.0 2.7 2 1 0 2 2 2 1 Zinc finger, ZZ type zf-4CXXC_R1 PF10497.4 EEQ29344.1 - 0.0012 18.9 10.6 0.0012 18.9 7.3 2.3 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EEQ29344.1 - 0.026 13.9 0.1 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Baculo_IE-1 PF05290.6 EEQ29344.1 - 0.09 12.5 6.6 0.027 14.2 0.9 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Sulfatase PF00884.18 EEQ29345.1 - 2.7e-17 62.9 0.1 5.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EEQ29345.1 - 3.5e-05 23.2 0.0 6.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EEQ29345.1 - 0.023 13.1 0.0 0.032 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4100 PF13352.1 EEQ29346.1 - 0.083 12.3 0.1 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) Lyase_1 PF00206.15 EEQ29347.1 - 1.9e-84 283.5 0.0 2.8e-84 282.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EEQ29347.1 - 3e-26 91.2 0.0 8e-26 89.9 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal AMP-binding PF00501.23 EEQ29348.1 - 8.3e-72 241.8 0.0 1.2e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ29348.1 - 3.7e-10 40.6 0.0 7.8e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M36 PF02128.10 EEQ29349.1 - 7.7e-160 531.8 9.4 7.7e-160 531.8 6.5 1.5 2 0 0 2 2 2 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EEQ29349.1 - 4.4e-11 42.0 2.4 5.1e-10 38.6 1.8 2.3 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Aminotran_1_2 PF00155.16 EEQ29350.1 - 4.2e-43 147.6 0.0 5.1e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEQ29350.1 - 2.6e-10 39.9 0.0 5.9e-10 38.7 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEQ29350.1 - 4.1e-07 29.0 0.0 6.3e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EEQ29350.1 - 5.9e-07 28.0 0.0 9e-07 27.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEQ29350.1 - 9.4e-07 28.1 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.2 EEQ29350.1 - 0.04 12.4 0.0 0.047 12.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.8 EEQ29350.1 - 0.13 10.8 0.0 0.34 9.5 0.0 1.9 1 1 0 1 1 1 0 Allinase ABC2_membrane PF01061.19 EEQ29351.1 - 1.3e-35 122.4 21.5 2.3e-35 121.7 14.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EEQ29351.1 - 2e-27 96.1 0.0 4e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEQ29351.1 - 8e-07 29.2 0.3 7.6e-06 26.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain hEGF PF12661.2 EEQ29351.1 - 8.2e-06 25.5 15.1 0.007 16.3 1.2 2.9 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_2 PF07974.8 EEQ29351.1 - 0.00034 20.7 12.0 0.00034 20.7 8.3 3.6 4 0 0 4 4 3 2 EGF-like domain AAA_29 PF13555.1 EEQ29351.1 - 0.0024 17.3 0.1 0.005 16.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EEQ29351.1 - 0.0054 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ29351.1 - 0.0075 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEQ29351.1 - 0.0091 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ29351.1 - 0.011 16.6 0.0 0.023 15.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EEQ29351.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EEQ29351.1 - 0.023 14.1 0.0 0.054 12.9 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EEQ29351.1 - 0.029 14.2 0.1 0.094 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EEQ29351.1 - 0.029 14.6 0.1 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ29351.1 - 0.04 14.2 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1212 PF06738.7 EEQ29351.1 - 0.061 12.7 1.9 0.15 11.4 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) AAA_16 PF13191.1 EEQ29351.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EEQ29351.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glycophorin_A PF01102.13 EEQ29351.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.4 3 0 0 3 3 2 0 Glycophorin A ABC2_membrane_3 PF12698.2 EEQ29351.1 - 0.41 9.6 40.4 0.5 9.3 25.8 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein Laminin_EGF PF00053.19 EEQ29351.1 - 1.4 8.9 29.0 0.53 10.2 6.0 3.1 2 1 1 3 3 2 0 Laminin EGF-like (Domains III and V) EGF PF00008.22 EEQ29351.1 - 4.7 7.2 23.2 0.89 9.5 6.1 3.1 3 0 0 3 3 2 0 EGF-like domain MFS_1 PF07690.11 EEQ29352.1 - 2.8e-18 65.7 42.9 2.3e-15 56.1 8.3 2.6 2 1 0 3 3 3 2 Major Facilitator Superfamily TerC PF03741.11 EEQ29352.1 - 0.014 14.8 0.1 0.014 14.8 0.1 2.8 2 1 0 2 2 2 0 Integral membrane protein TerC family Pkinase PF00069.20 EEQ29353.1 - 4.7e-12 45.6 0.0 1.2e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29353.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Cornichon PF03311.9 EEQ29354.1 - 3.6e-54 182.3 12.1 4.1e-54 182.1 8.4 1.0 1 0 0 1 1 1 1 Cornichon protein PSP1 PF04468.7 EEQ29355.1 - 3.9e-31 106.8 1.5 6.6e-31 106.1 1.0 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 EEQ29355.1 - 0.3 8.9 0.4 0.46 8.3 0.3 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Tis11B_N PF04553.7 EEQ29355.1 - 0.47 10.6 6.9 9.5 6.4 0.7 2.8 2 0 0 2 2 2 0 Tis11B like protein, N terminus Nfu_N PF08712.6 EEQ29356.1 - 1.1e-26 92.2 0.0 3e-26 90.8 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EEQ29356.1 - 5.5e-23 80.5 0.1 1.1e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 NifU-like domain RasGEF PF00617.14 EEQ29357.1 - 4.4e-45 153.7 0.1 7.4e-45 152.9 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEQ29357.1 - 3.7e-12 46.2 0.0 8.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EEQ29357.1 - 3.9e-10 40.2 0.0 9.8e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 EEQ29357.1 - 0.02 14.3 0.5 2.4 7.5 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain Ras PF00071.17 EEQ29357.1 - 0.021 14.2 0.0 0.08 12.3 0.0 1.9 1 1 0 1 1 1 0 Ras family AAA_16 PF13191.1 EEQ29357.1 - 0.027 14.4 0.3 0.61 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain CotJB PF12652.2 EEQ29357.1 - 0.042 13.9 1.4 8.7 6.4 0.1 2.8 2 0 0 2 2 2 0 CotJB protein AAA_33 PF13671.1 EEQ29357.1 - 0.075 12.9 0.1 0.38 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EEQ29357.1 - 0.16 11.5 0.1 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein API5 PF05918.6 EEQ29358.1 - 0.89 7.9 4.0 1.1 7.7 2.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Complex1_LYR_2 PF13233.1 EEQ29359.1 - 4e-20 72.2 0.3 4.9e-20 71.9 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like ABC_tran PF00005.22 EEQ29360.1 - 1.2e-47 161.6 0.0 6.6e-28 97.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ29360.1 - 1.6e-17 63.8 20.7 1.6e-13 50.6 4.3 4.4 3 1 2 5 5 4 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEQ29360.1 - 4.2e-09 36.7 0.0 0.033 14.1 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EEQ29360.1 - 5.6e-09 36.6 0.0 7.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ29360.1 - 2e-06 27.2 0.1 0.043 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EEQ29360.1 - 2.3e-06 26.8 0.0 0.02 14.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ29360.1 - 7.1e-06 26.1 0.1 0.045 13.7 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EEQ29360.1 - 1.1e-05 24.9 0.0 0.053 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EEQ29360.1 - 2.2e-05 23.8 0.0 0.15 11.2 0.0 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EEQ29360.1 - 3.1e-05 23.5 0.0 0.073 12.5 0.0 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_17 PF13207.1 EEQ29360.1 - 4.1e-05 24.3 0.2 0.2 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEQ29360.1 - 0.00015 21.8 0.3 0.47 10.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEQ29360.1 - 0.00016 20.7 0.2 0.3 10.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 EEQ29360.1 - 0.00022 21.1 0.0 0.035 14.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 EEQ29360.1 - 0.00025 20.7 0.0 0.37 10.4 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EEQ29360.1 - 0.00034 21.1 0.1 1.1 9.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 EEQ29360.1 - 0.00049 19.7 0.0 0.42 10.1 0.1 3.1 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EEQ29360.1 - 0.00054 18.9 0.0 0.61 8.9 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EEQ29360.1 - 0.0007 19.1 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain ArgK PF03308.11 EEQ29360.1 - 0.0008 18.2 0.1 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 EEQ29360.1 - 0.0029 17.9 0.3 2.6 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEQ29360.1 - 0.0062 16.4 0.0 0.75 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EEQ29360.1 - 0.0063 16.3 1.4 0.011 15.5 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 EEQ29360.1 - 0.0097 16.0 0.0 2.2 8.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.20 EEQ29360.1 - 0.013 15.0 0.6 0.039 13.4 0.1 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 EEQ29360.1 - 0.015 14.6 0.1 7.4 5.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EEQ29360.1 - 0.037 13.7 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase SbcCD_C PF13558.1 EEQ29360.1 - 0.049 13.5 0.0 12 5.9 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EEQ29360.1 - 0.075 12.6 1.7 9.5 5.8 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 EEQ29360.1 - 0.12 12.1 0.3 5.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.4 EEQ29360.1 - 0.13 10.8 0.4 1.5 7.3 0.2 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.4 EEQ29360.1 - 0.13 11.7 0.1 21 4.5 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EEQ29360.1 - 0.15 11.4 3.3 3.4 7.0 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EEQ29360.1 - 0.15 12.2 0.2 6 7.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EEQ29360.1 - 0.3 10.0 0.0 0.57 9.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 EEQ29360.1 - 0.43 10.2 0.7 4.9 6.8 0.2 2.2 2 0 0 2 2 2 0 NTPase Cyclin PF08613.6 EEQ29361.1 - 1.9e-06 28.3 0.0 3.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEQ29361.1 - 1.8e-05 24.3 0.0 3.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1522 PF07482.6 EEQ29361.1 - 0.22 11.6 1.0 0.44 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) CCT_2 PF09425.5 EEQ29361.1 - 0.5 9.9 4.9 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Divergent CCT motif RAP1 PF07218.6 EEQ29361.1 - 1.9 6.4 3.3 2.7 5.9 2.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SBF PF01758.11 EEQ29362.1 - 5.4e-49 166.1 12.5 5.4e-49 166.1 8.7 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family Nop14 PF04147.7 EEQ29364.1 - 2.8 5.7 10.0 4 5.2 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family ATP_bind_3 PF01171.15 EEQ29367.1 - 3.7e-19 68.9 0.0 6.1e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EEQ29367.1 - 0.0018 18.6 0.0 0.0041 17.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EEQ29367.1 - 0.0096 14.5 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 EEQ29367.1 - 0.024 14.0 0.8 0.024 14.0 0.6 2.6 3 0 0 3 3 3 0 RecR protein zf-UBR PF02207.15 EEQ29367.1 - 0.039 13.6 6.4 0.57 9.9 0.5 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Acetyltransf_8 PF13523.1 EEQ29368.1 - 4.8e-29 101.2 0.0 7e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EEQ29369.1 - 9.2e-26 90.5 0.0 1.3e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29369.1 - 8.2e-06 25.0 0.0 1.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ29369.1 - 0.0072 15.4 0.1 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ29369.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like GNVR PF13807.1 EEQ29372.1 - 0.23 11.2 0.9 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase DUF3951 PF13131.1 EEQ29373.1 - 0.018 14.8 1.7 0.073 12.8 0.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3951) zf-LITAF-like PF10601.4 EEQ29373.1 - 0.091 12.6 7.0 3 7.7 1.3 2.6 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain DUF373 PF04123.8 EEQ29373.1 - 1.3 7.9 5.3 4.4 6.2 4.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF1992 PF09350.5 EEQ29374.1 - 7.1e-22 77.0 0.2 2.8e-21 75.1 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) p450 PF00067.17 EEQ29376.1 - 9.9e-51 172.6 0.0 1.6e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EEQ29377.1 - 5.2e-05 22.8 0.5 0.00018 21.1 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEQ29377.1 - 0.012 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 F-box domain Lactonase PF10282.4 EEQ29377.1 - 0.07 12.2 0.1 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller SRP40_C PF05022.7 EEQ29378.1 - 1e-22 80.4 0.1 2.9e-22 78.9 0.1 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain Sec3-PIP2_bind PF15277.1 EEQ29379.1 - 5.8e-31 106.1 0.2 1.1e-30 105.3 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.4 EEQ29379.1 - 2.6e-24 85.4 0.3 2.6e-24 85.4 0.2 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec3 Vps52 PF04129.7 EEQ29379.1 - 0.44 9.0 0.2 0.61 8.5 0.1 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family DOCK-C2 PF14429.1 EEQ29380.1 - 1.3e-38 132.5 0.0 3.7e-38 131.0 0.0 1.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EEQ29380.1 - 2.3e-13 49.8 0.0 5.8e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EEQ29380.1 - 8.7e-05 21.8 0.0 0.00024 20.4 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEQ29380.1 - 0.0014 18.1 0.2 0.017 14.6 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain Glyco_hydro_20 PF00728.17 EEQ29381.1 - 3.6e-98 328.9 0.2 4.5e-98 328.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EEQ29381.1 - 1.7e-23 83.6 0.1 3.8e-22 79.3 0.0 2.3 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EEQ29381.1 - 1.5e-05 25.5 0.0 2.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 NmrA PF05368.8 EEQ29382.1 - 4.8e-18 65.2 0.0 1.2e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EEQ29382.1 - 0.03 14.3 0.4 0.11 12.4 0.3 1.8 1 1 0 1 1 1 0 NADH(P)-binding Ribosomal_S8e PF01201.17 EEQ29384.1 - 1.8e-48 164.0 1.2 2e-48 163.8 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Ribonuclease_T2 PF00445.13 EEQ29385.1 - 1.6e-45 155.0 0.3 1.6e-45 155.0 0.2 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family DUF1792 PF08759.6 EEQ29385.1 - 0.011 15.3 0.2 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) Tissue_fac PF01108.12 EEQ29385.1 - 1.3 8.7 3.5 8.8 6.1 0.0 2.4 1 1 1 2 2 2 0 Tissue factor Na_sulph_symp PF00939.14 EEQ29386.1 - 5e-15 55.3 25.8 8.5e-15 54.5 17.9 1.4 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region DUF3290 PF11694.3 EEQ29386.1 - 0.027 14.2 0.5 0.089 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) FxsA PF04186.8 EEQ29386.1 - 0.21 11.2 9.1 0.12 11.9 3.7 2.6 1 1 1 2 2 2 0 FxsA cytoplasmic membrane protein SPX PF03105.14 EEQ29387.1 - 1.4e-46 159.5 0.7 6e-46 157.4 0.5 2.0 1 1 0 1 1 1 1 SPX domain Peptidase_S28 PF05577.7 EEQ29388.1 - 1.7e-53 181.7 0.2 8.8e-53 179.4 0.2 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EEQ29388.1 - 0.013 14.7 0.1 0.036 13.2 0.0 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_S7 PF00177.16 EEQ29389.1 - 1e-29 103.0 0.0 3.3e-29 101.3 0.0 1.8 3 0 0 3 3 3 1 Ribosomal protein S7p/S5e DUF1013 PF06242.6 EEQ29389.1 - 0.044 13.7 0.5 0.32 10.9 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1013) Na_Ca_ex PF01699.19 EEQ29390.1 - 2.1e-38 131.0 36.8 1.1e-22 80.1 7.2 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cytochrom_B_N PF00033.14 EEQ29390.1 - 0.78 9.0 10.2 2.1 7.6 0.0 3.4 3 1 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB MFS_1 PF07690.11 EEQ29391.1 - 8e-28 97.1 31.3 8e-28 97.1 21.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DAO PF01266.19 EEQ29392.1 - 9.5e-45 153.0 0.1 1.3e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 EEQ29392.1 - 0.0004 20.2 0.0 0.0033 17.2 0.0 2.2 2 0 0 2 2 2 1 ThiF family GIDA PF01134.17 EEQ29392.1 - 0.00058 18.8 0.0 0.79 8.5 0.0 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EEQ29392.1 - 0.0007 19.5 0.0 0.0019 18.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ29392.1 - 0.0028 17.5 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ29392.1 - 0.0039 16.9 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EEQ29392.1 - 0.02 13.7 0.5 0.067 12.0 0.3 1.8 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EEQ29392.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEQ29392.1 - 0.047 12.7 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EEQ29392.1 - 0.048 13.4 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EEQ29392.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thioredoxin PF00085.15 EEQ29393.1 - 4.9e-33 112.9 0.0 5.9e-25 86.9 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EEQ29393.1 - 6e-13 48.9 0.0 3.3e-06 27.0 0.0 4.1 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EEQ29393.1 - 1.5e-05 25.1 0.0 0.046 13.9 0.0 4.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEQ29393.1 - 0.00046 20.2 0.0 0.011 15.8 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 EEQ29393.1 - 0.00077 19.3 0.0 0.38 10.6 0.0 2.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EEQ29393.1 - 0.002 18.0 0.2 0.029 14.3 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EEQ29393.1 - 0.15 11.8 0.0 0.53 10.1 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin domain DUF3827 PF12877.2 EEQ29393.1 - 4.9 5.1 8.6 7.3 4.5 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ETC_C1_NDUFA5 PF04716.9 EEQ29394.1 - 2.3e-22 78.2 0.3 2.3e-22 78.2 0.2 2.6 3 0 0 3 3 3 1 ETC complex I subunit conserved region Ku_PK_bind PF08785.6 EEQ29394.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Ku C terminal domain like Coatomer_WDAD PF04053.9 EEQ29395.1 - 3.1e-171 570.0 0.0 6.3e-171 569.0 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EEQ29395.1 - 1.2e-46 154.9 7.6 2.2e-10 39.9 0.2 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EEQ29395.1 - 0.0021 16.2 3.0 0.056 11.5 0.1 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EEQ29395.1 - 0.005 16.5 0.0 2.9 7.7 0.0 3.2 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 EEQ29396.1 - 1.2e-70 237.6 0.0 1.5e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29396.1 - 5.4e-33 114.1 0.0 7.3e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEQ29396.1 - 5.6e-08 33.1 0.1 5.6e-08 33.1 0.1 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEQ29396.1 - 0.00041 19.3 0.0 0.00062 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SWIRM PF04433.12 EEQ29397.1 - 2.1e-16 59.7 0.0 5.5e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EEQ29397.1 - 3.7e-10 39.1 4.9 6.6e-10 38.3 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EEQ29397.1 - 4.4e-08 33.0 0.0 1.2e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PG_binding_1 PF01471.13 EEQ29397.1 - 0.016 15.1 0.0 0.06 13.3 0.0 2.0 1 0 0 1 1 1 0 Putative peptidoglycan binding domain WD40 PF00400.27 EEQ29399.1 - 6.7e-26 89.1 8.3 4.8e-06 26.2 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.16 EEQ29400.1 - 1e-32 113.1 10.4 1e-32 113.1 7.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 Aconitase PF00330.15 EEQ29401.1 - 3.9e-184 612.4 0.0 4.7e-184 612.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEQ29401.1 - 3.1e-43 147.0 0.0 5.9e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Pribosyltran PF00156.22 EEQ29402.1 - 8.3e-17 61.0 0.1 1.5e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GTP_cyclohydro2 PF00925.15 EEQ29402.1 - 0.053 12.7 0.0 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 GTP cyclohydrolase II MTHFR PF02219.12 EEQ29403.1 - 1.6e-116 388.3 0.0 2.3e-116 387.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.6 EEQ29403.1 - 0.11 12.2 0.1 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Galanin PF01296.13 EEQ29404.1 - 0.14 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Galanin DUF2418 PF10332.4 EEQ29405.1 - 8.4e-34 115.8 0.5 1.4e-33 115.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Adeno_E3_CR2 PF02439.10 EEQ29405.1 - 0.085 12.4 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TcdA_TcdB_pore PF12920.2 EEQ29405.1 - 0.15 9.9 0.1 0.21 9.4 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain ATP-synt_F PF01990.12 EEQ29406.1 - 9.2e-31 106.0 0.0 1.1e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 EEQ29406.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 E1_DerP2_DerF2 PF02221.10 EEQ29407.1 - 1.8e-24 86.5 0.4 2.2e-24 86.2 0.3 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EEQ29407.1 - 3.1e-05 24.0 0.1 0.00029 20.8 0.1 2.0 1 1 0 1 1 1 1 ML-like domain NPCBM_assoc PF10633.4 EEQ29407.1 - 0.13 12.3 0.3 0.47 10.5 0.0 2.1 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase NOGCT PF08155.6 EEQ29408.1 - 3.5e-29 100.2 1.5 7.1e-29 99.2 1.0 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EEQ29408.1 - 2.1e-26 91.5 0.8 5.4e-26 90.2 0.6 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EEQ29408.1 - 1e-14 54.4 0.0 2.3e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ29408.1 - 1.3e-07 31.0 0.0 3.6e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EEQ29408.1 - 0.00015 22.2 0.0 0.00047 20.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EEQ29408.1 - 0.0014 18.4 0.0 0.6 9.9 0.0 2.7 1 1 1 2 2 2 2 Dynamin family DUF506 PF04720.7 EEQ29408.1 - 0.065 12.8 3.3 0.62 9.6 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Acetyltransf_1 PF00583.19 EEQ29409.1 - 5.6e-09 35.9 0.0 9.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ29409.1 - 9.2e-09 35.3 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ29409.1 - 2.3e-05 24.0 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ29409.1 - 0.0022 18.0 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ29409.1 - 0.027 14.3 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nucleoplasmin PF03066.10 EEQ29409.1 - 0.042 13.3 1.6 0.065 12.7 1.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Acetyltransf_4 PF13420.1 EEQ29409.1 - 0.049 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ29409.1 - 0.076 12.8 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2457 PF10446.4 EEQ29409.1 - 1.3 7.6 8.4 2.1 6.9 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 EEQ29409.1 - 3.3 8.0 8.0 3.9 7.8 4.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp_protease PF09668.5 EEQ29410.1 - 6.8e-61 203.3 0.2 1e-60 202.7 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EEQ29410.1 - 1.6e-11 44.5 0.0 5.1e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.18 EEQ29410.1 - 3.3e-09 36.0 0.0 5.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEQ29410.1 - 1.4e-07 31.1 0.0 2.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain gag-asp_proteas PF13975.1 EEQ29410.1 - 2.8e-06 27.0 0.0 6.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EEQ29410.1 - 4.6e-06 26.5 0.0 8.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EEQ29410.1 - 0.00017 21.4 0.0 0.00044 20.1 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 EEQ29410.1 - 0.00062 19.4 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 EEQ29410.1 - 0.0045 16.4 0.0 0.0088 15.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UN_NPL4 PF11543.3 EEQ29410.1 - 0.0085 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 NAD_binding_7 PF13241.1 EEQ29410.1 - 0.045 13.9 0.0 0.31 11.3 0.0 2.2 3 0 0 3 3 2 0 Putative NAD(P)-binding Fungal_trans_2 PF11951.3 EEQ29411.1 - 1.9e-19 69.5 0.3 1.6e-14 53.3 0.9 3.0 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ29411.1 - 4.5e-07 29.6 11.9 7.6e-07 28.9 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ29411.1 - 0.011 14.5 5.1 0.026 13.4 0.9 2.7 2 1 0 2 2 2 0 Fungal specific transcription factor domain GalP_UDP_transf PF01087.17 EEQ29413.1 - 7.4e-69 231.4 0.1 3.3e-67 226.0 0.0 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EEQ29413.1 - 1.4e-55 187.3 0.1 3.8e-55 185.9 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain Erg28 PF03694.8 EEQ29414.1 - 5.7e-40 135.7 2.4 7e-40 135.5 1.7 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF2417 PF10329.4 EEQ29414.1 - 0.048 13.0 3.4 0.22 10.9 0.3 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) adh_short PF00106.20 EEQ29415.1 - 1e-23 84.1 0.0 1.4e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ29415.1 - 1.5e-11 44.5 0.0 2.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ29415.1 - 8.2e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEQ29415.1 - 0.00056 19.9 0.0 0.00092 19.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEQ29415.1 - 0.0031 16.4 0.0 0.0046 15.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EEQ29415.1 - 0.0046 16.4 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEQ29415.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.13 EEQ29415.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 EEQ29416.1 - 8.9e-10 38.5 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ29416.1 - 1.5e-07 31.7 0.0 3.5e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ29416.1 - 4.3e-06 26.4 0.0 0.00026 20.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ29416.1 - 1e-05 26.0 0.0 2.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ29416.1 - 3.2e-05 24.3 0.0 0.0001 22.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ29416.1 - 0.00017 20.6 0.0 0.00029 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EEQ29416.1 - 0.00062 19.7 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEQ29416.1 - 0.0053 16.7 0.1 0.021 14.8 0.0 1.9 2 1 0 3 3 3 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EEQ29416.1 - 0.026 13.7 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DUF1923 PF09083.5 EEQ29417.1 - 0.14 11.6 1.9 2 7.9 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1923) Spc97_Spc98 PF04130.8 EEQ29419.1 - 3.4e-134 448.1 0.5 4.5e-134 447.7 0.3 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 EEQ29420.1 - 4.2e-53 179.4 0.1 6e-53 178.9 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEQ29420.1 - 8.9e-14 50.4 0.2 2.3e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EEQ29420.1 - 0.021 14.5 0.1 0.71 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Methyltransf_8 PF05148.10 EEQ29421.1 - 3.8e-59 199.9 0.3 7.4e-56 189.2 0.0 2.8 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EEQ29421.1 - 2.7e-06 27.7 0.0 1e-05 25.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ29421.1 - 0.065 12.8 0.0 1.4 8.4 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ29421.1 - 0.084 13.2 0.0 4.2 7.7 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EEQ29421.1 - 0.12 12.0 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FabA PF07977.8 EEQ29421.1 - 0.14 11.6 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 FabA-like domain Abhydrolase_6 PF12697.2 EEQ29423.1 - 3e-25 89.4 0.6 4.7e-25 88.8 0.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ29423.1 - 2.9e-14 53.2 0.2 1.2e-10 41.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ29423.1 - 4.5e-09 36.2 0.4 9.7e-09 35.1 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ29423.1 - 0.00027 20.5 0.1 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EEQ29423.1 - 0.0015 18.8 0.0 0.0026 18.0 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Peptidase_S28 PF05577.7 EEQ29423.1 - 0.012 14.1 0.0 0.021 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_8 PF06259.7 EEQ29423.1 - 0.03 13.8 0.1 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase F-box-like PF12937.2 EEQ29424.1 - 3.6e-05 23.4 1.1 8.9e-05 22.1 0.8 1.7 1 0 0 1 1 1 1 F-box-like NAD_binding_2 PF03446.10 EEQ29425.1 - 6.9e-33 113.7 0.1 6.9e-33 113.7 0.1 2.2 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEQ29425.1 - 4.1e-13 49.5 0.3 1.7e-12 47.6 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EEQ29425.1 - 3e-10 40.2 3.8 1.4e-09 38.0 2.6 2.0 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EEQ29425.1 - 6.7e-10 39.1 0.1 1.4e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EEQ29425.1 - 0.00016 21.1 0.1 0.00031 20.1 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EEQ29425.1 - 0.00057 19.8 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain OCD_Mu_crystall PF02423.10 EEQ29425.1 - 0.0014 17.5 0.3 0.0028 16.4 0.1 1.6 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_3 PF03447.11 EEQ29425.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EEQ29425.1 - 0.016 15.7 0.0 0.053 14.0 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EEQ29425.1 - 0.033 14.4 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_72 PF03198.9 EEQ29426.1 - 9.2e-120 399.3 2.5 1.3e-119 398.8 1.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EEQ29426.1 - 3.5e-23 81.8 1.1 7.9e-23 80.7 0.8 1.6 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EEQ29426.1 - 4.9e-05 22.3 0.3 0.00015 20.8 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EEQ29426.1 - 0.079 12.1 0.6 4.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) BAR_2 PF10455.4 EEQ29428.1 - 1.4e-61 207.9 0.2 2.1e-61 207.3 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EEQ29428.1 - 3.2e-19 69.3 4.7 5.2e-18 65.4 3.3 2.0 1 1 0 1 1 1 1 BAR domain Mod_r PF07200.8 EEQ29428.1 - 0.17 11.8 2.4 0.33 10.8 0.2 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 EEQ29428.1 - 0.19 10.8 4.5 2 7.5 0.5 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATP-synt_B PF00430.13 EEQ29428.1 - 0.47 10.2 4.3 0.57 9.9 0.5 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Dabb PF07876.7 EEQ29430.1 - 2.3e-16 60.0 0.0 2.5e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4123 PF13503.1 EEQ29430.1 - 0.13 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) Pyrid_oxidase_2 PF13883.1 EEQ29430.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Arv1 PF04161.8 EEQ29431.1 - 8.8e-40 136.8 0.2 4.2e-34 118.2 0.0 2.3 2 0 0 2 2 2 2 Arv1-like family DUF619 PF04768.8 EEQ29432.1 - 4.2e-52 176.0 0.0 1.3e-51 174.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) DUF2781 PF10914.3 EEQ29433.1 - 1.2e-30 106.3 11.5 1.7e-30 105.8 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Nucleoporin_C PF03177.9 EEQ29434.1 - 6.4e-120 401.4 2.3 7.8e-120 401.1 1.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EEQ29434.1 - 8.3e-84 281.7 0.0 1.1e-83 281.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like YqeY PF09424.5 EEQ29435.1 - 5.4e-21 74.9 2.7 6.3e-21 74.7 1.9 1.0 1 0 0 1 1 1 1 Yqey-like protein Rot1 PF10681.4 EEQ29436.1 - 3.6e-88 294.4 0.1 4.1e-88 294.2 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.15 EEQ29437.1 - 1.1e-28 100.3 0.0 1.7e-28 99.6 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 EEQ29438.1 - 4.3e-14 51.8 0.1 5.2e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 EEQ29438.1 - 0.14 11.6 0.0 0.81 9.1 0.0 2.1 2 0 0 2 2 2 0 PhnA protein Xpo1 PF08389.7 EEQ29439.1 - 5.3e-28 97.7 0.1 1.1e-26 93.5 0.0 3.1 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.1 EEQ29439.1 - 0.0042 17.3 0.0 0.06 13.6 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EEQ29439.1 - 0.01 15.8 0.0 6.8 7.0 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 EEQ29439.1 - 0.015 15.7 0.0 0.32 11.5 0.0 3.5 2 1 1 3 3 3 0 HEAT-like repeat Glyco_transf_90 PF05686.7 EEQ29440.1 - 6.8e-15 54.6 0.2 3.2e-12 45.8 0.3 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Fungal_trans PF04082.13 EEQ29441.1 - 2.4e-59 200.3 0.4 3.7e-59 199.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EEQ29441.1 - 0.00058 20.0 13.9 0.0062 16.7 1.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ29441.1 - 0.0013 18.9 15.1 0.0083 16.4 2.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ29441.1 - 1.4 9.3 11.0 0.17 12.2 2.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain EF-hand_7 PF13499.1 EEQ29443.1 - 1.1e-07 31.9 0.0 3.1e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ29443.1 - 2.9e-06 26.7 0.0 0.0013 18.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.1 EEQ29443.1 - 2e-05 24.3 0.0 0.00011 22.0 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EEQ29443.1 - 0.00011 21.2 0.2 0.049 12.9 0.0 2.8 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EEQ29443.1 - 0.00011 21.7 0.2 0.0049 16.4 0.0 2.9 3 1 0 3 3 3 1 EF-hand domain pair Yippee-Mis18 PF03226.9 EEQ29444.1 - 0.028 14.4 0.2 11 6.0 0.0 2.5 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2197 PF09963.4 EEQ29444.1 - 0.036 14.0 0.1 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) Mu-like_Com PF10122.4 EEQ29444.1 - 0.12 11.4 0.5 2.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com CD52 PF15116.1 EEQ29444.1 - 0.12 12.1 0.9 0.35 10.7 0.6 1.7 1 0 0 1 1 1 0 CAMPATH-1 antigen zf-DHHC PF01529.15 EEQ29444.1 - 0.92 8.8 6.0 0.15 11.4 1.0 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF4637 PF15470.1 EEQ29444.1 - 1 8.9 5.0 0.42 10.2 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) CENP-B_dimeris PF09026.5 EEQ29444.1 - 3.7 7.8 7.2 7.2 6.9 5.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_M3 PF01432.15 EEQ29445.1 - 1.3e-166 555.1 0.2 1.8e-166 554.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 FA_desaturase PF00487.19 EEQ29446.1 - 1.6e-18 67.1 10.3 1.6e-18 67.1 7.1 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EEQ29446.1 - 4.4e-17 61.6 0.1 1.1e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Amidase PF01425.16 EEQ29449.1 - 4e-76 256.6 0.0 5.6e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Penicillinase_R PF03965.11 EEQ29449.1 - 0.21 11.6 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor MOSC PF03473.12 EEQ29450.1 - 1.4e-12 47.2 0.0 2.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EEQ29450.1 - 6.9e-11 41.9 0.0 1.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain APH PF01636.18 EEQ29453.1 - 1.8e-07 31.1 0.2 2.9e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ29453.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain SAP30_Sin3_bdg PF13867.1 EEQ29454.1 - 3.3e-16 58.8 0.3 8.5e-16 57.5 0.0 1.8 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF4466 PF14725.1 EEQ29454.1 - 0.0063 15.8 0.3 0.088 12.0 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4466) TFIIA PF03153.8 EEQ29454.1 - 3.7 7.3 9.7 5 6.9 6.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BRO1 PF03097.13 EEQ29455.1 - 2.8e-124 414.7 0.3 2.8e-124 414.7 0.2 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EEQ29455.1 - 2.2e-97 325.5 15.0 3.6e-97 324.9 10.4 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CTDII PF01556.13 EEQ29456.1 - 9.5e-28 95.9 1.5 3.1e-21 75.0 0.1 3.4 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EEQ29456.1 - 2.2e-23 81.7 1.2 4.5e-23 80.7 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEQ29456.1 - 1.2e-10 41.2 19.9 3e-10 39.9 13.8 1.7 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EEQ29456.1 - 0.15 11.7 10.1 0.15 11.7 0.6 2.5 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Lon_C PF05362.8 EEQ29457.1 - 1.6e-62 210.4 0.0 3.5e-62 209.3 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EEQ29457.1 - 2.8e-39 134.9 1.6 3e-39 134.8 0.1 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EEQ29457.1 - 3.4e-22 79.0 0.0 8.4e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ29457.1 - 1.1e-06 28.4 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ29457.1 - 1.3e-06 28.4 0.0 3.3e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 EEQ29457.1 - 3.2e-06 26.6 0.0 7.6e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 EEQ29457.1 - 1.1e-05 25.5 0.2 0.00022 21.3 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_PrkA PF08298.6 EEQ29457.1 - 2.6e-05 23.0 0.1 8.4e-05 21.4 0.0 1.8 2 0 0 2 2 2 1 PrkA AAA domain AAA_17 PF13207.1 EEQ29457.1 - 4.4e-05 24.2 0.0 0.00025 21.8 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ29457.1 - 0.0001 22.3 0.5 0.00079 19.4 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EEQ29457.1 - 0.00012 21.2 0.0 0.00095 18.2 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EEQ29457.1 - 0.0022 18.2 1.8 0.028 14.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEQ29457.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EEQ29457.1 - 0.018 14.7 0.3 1 9.0 0.0 3.1 2 1 1 3 3 3 0 NTPase SKI PF01202.17 EEQ29457.1 - 0.02 14.7 0.1 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 EEQ29457.1 - 0.025 14.2 0.0 0.064 12.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EEQ29457.1 - 0.031 13.6 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EEQ29457.1 - 0.04 14.0 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.11 EEQ29457.1 - 0.04 13.1 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EEQ29457.1 - 0.048 13.1 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EEQ29457.1 - 0.069 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEQ29457.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEQ29457.1 - 1 9.6 4.9 0.69 10.2 0.0 2.8 3 0 0 3 3 3 0 ABC transporter Pkinase PF00069.20 EEQ29460.1 - 2.2e-11 43.3 0.1 4.4e-10 39.1 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29460.1 - 7.9e-10 38.2 0.0 5.9e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Mob1_phocein PF03637.12 EEQ29461.1 - 1.4e-23 83.4 0.3 2.8e-23 82.4 0.0 1.5 2 0 0 2 2 2 1 Mob1/phocein family cobW PF02492.14 EEQ29462.1 - 2.2e-45 154.3 0.6 2.9e-45 153.8 0.4 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EEQ29462.1 - 1.1e-06 28.2 0.0 1.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain ATP_bind_1 PF03029.12 EEQ29462.1 - 6.9e-05 22.5 0.1 0.00016 21.3 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EEQ29462.1 - 0.001 19.4 0.3 0.014 15.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ29462.1 - 0.0023 17.9 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EEQ29462.1 - 0.0031 17.4 0.5 0.013 15.4 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.1 EEQ29462.1 - 0.0051 16.4 0.1 1.2 8.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 EEQ29462.1 - 0.0056 16.3 0.2 0.072 12.7 0.0 2.5 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EEQ29462.1 - 0.0069 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase GTP_EFTU PF00009.22 EEQ29462.1 - 0.0098 15.3 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EEQ29462.1 - 0.015 15.4 0.3 0.051 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EEQ29462.1 - 0.016 14.0 0.2 0.44 9.2 0.0 2.5 3 0 0 3 3 3 0 ArgK protein ABC_tran PF00005.22 EEQ29462.1 - 0.018 15.3 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 EEQ29462.1 - 0.18 11.0 2.0 5.9 6.1 0.1 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B HAUS6_N PF14661.1 EEQ29463.1 - 1.3e-64 217.9 0.1 2.4e-64 217.0 0.1 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.1 EEQ29464.1 - 6.3e-47 159.3 0.1 7.8e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EEQ29464.1 - 0.002 18.1 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 HD domain BHD_3 PF10405.4 EEQ29465.1 - 3.9e-28 96.9 0.1 6.8e-28 96.1 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EEQ29465.1 - 2.6e-27 95.0 1.4 3.5e-27 94.5 0.1 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_2 PF10404.4 EEQ29465.1 - 1.6e-17 63.5 0.0 4.6e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EEQ29465.1 - 8e-17 60.5 0.1 1.8e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 EEQ29465.1 - 0.0041 17.3 0.0 0.016 15.3 0.0 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF1774 PF08611.5 EEQ29466.1 - 9e-23 80.2 7.6 9e-23 80.2 5.3 2.1 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Glyco_transf_54 PF04666.8 EEQ29466.1 - 0.01 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MIG-14_Wnt-bd PF06664.7 EEQ29466.1 - 0.014 14.2 6.2 0.024 13.4 0.1 2.2 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Peptidase_M28 PF04389.12 EEQ29467.1 - 5.8e-29 101.0 0.0 1.1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 EEQ29467.1 - 0.0013 18.0 0.2 0.1 11.8 0.0 2.2 2 0 0 2 2 2 2 Nicastrin Peptidase_M20 PF01546.23 EEQ29467.1 - 0.016 14.6 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 DUF2891 PF11199.3 EEQ29467.1 - 0.058 11.9 0.0 0.089 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) R3H-assoc PF13902.1 EEQ29468.1 - 1.7e-32 112.1 15.1 3.1e-32 111.2 10.4 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EEQ29468.1 - 0.0047 16.5 0.0 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 R3H domain DUF1945 PF09178.5 EEQ29468.1 - 0.049 13.5 0.3 1.6 8.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1945) SpoVR PF04293.8 EEQ29468.1 - 5.5 5.2 6.9 8 4.7 4.8 1.1 1 0 0 1 1 1 0 SpoVR like protein Hist_deacetyl PF00850.14 EEQ29469.1 - 2.3e-59 201.2 0.1 5.2e-59 200.0 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain zf-AN1 PF01428.11 EEQ29470.1 - 2e-24 85.1 22.0 3.1e-13 49.3 5.4 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EEQ29470.1 - 0.0006 19.9 12.9 0.045 13.9 1.7 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.16 EEQ29470.1 - 0.0018 18.0 4.7 0.0018 18.0 3.3 3.1 2 1 0 2 2 2 1 IBR domain Thymidylat_synt PF00303.14 EEQ29471.1 - 1.3e-110 368.6 0.0 1.5e-110 368.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Toxin_27 PF08099.6 EEQ29472.1 - 0.0058 16.5 7.5 0.0058 16.5 5.2 6.3 6 2 0 6 6 6 1 Scorpion calcine family Toxin_29 PF08116.6 EEQ29472.1 - 0.039 13.7 4.4 0.039 13.7 3.1 6.3 6 2 1 7 7 7 0 PhTx neurotoxin family TGT PF01702.13 EEQ29473.1 - 2.2e-91 305.3 0.0 2.9e-91 304.9 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Fungal_trans PF04082.13 EEQ29475.1 - 2.8e-21 75.5 0.5 7.5e-21 74.1 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ29475.1 - 3.8e-10 39.5 10.4 8.4e-10 38.3 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAS20 PF02064.10 EEQ29475.1 - 0.18 11.7 0.5 0.5 10.2 0.1 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor DND1_DSRM PF14709.1 EEQ29476.1 - 0.00025 21.2 0.0 0.00041 20.5 0.0 1.3 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EEQ29476.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.4 1 1 0 1 1 1 0 Double-stranded RNA binding motif APH PF01636.18 EEQ29480.1 - 1.9e-10 40.9 0.0 4.2e-05 23.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ29480.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.4 1 1 0 1 1 1 0 Protein kinase domain Glyco_hydro_18 PF00704.23 EEQ29481.1 - 1.5e-61 208.7 1.0 3.1e-30 105.7 0.0 2.6 2 1 1 3 3 3 2 Glycosyl hydrolases family 18 Tmemb_cc2 PF10267.4 EEQ29481.1 - 0.54 8.8 0.2 0.84 8.1 0.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Aspzincin_M35 PF14521.1 EEQ29482.1 - 3.6e-06 27.5 0.1 7.5e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Ala_racemase_N PF01168.15 EEQ29483.1 - 1.4e-35 122.8 0.0 1.8e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Inp1 PF12634.2 EEQ29483.1 - 0.046 13.4 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 Adaptin_N PF01602.15 EEQ29484.1 - 1.3e-122 409.8 4.5 1.7e-122 409.4 3.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EEQ29484.1 - 8.2e-41 138.5 0.0 2e-40 137.2 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EEQ29484.1 - 2.4e-18 66.5 0.0 7.7e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain efThoc1 PF11957.3 EEQ29488.1 - 1.5e-166 554.7 1.6 2.8e-166 553.8 1.1 1.4 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_12 PF13087.1 EEQ29489.1 - 7e-26 90.8 0.0 1.3e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ29489.1 - 8.9e-24 84.3 0.0 1.9e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ29489.1 - 1.2e-09 37.7 0.1 7.1e-09 35.2 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEQ29489.1 - 3.2e-06 26.8 0.0 0.00048 19.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EEQ29489.1 - 0.00012 21.7 0.1 0.098 12.1 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EEQ29489.1 - 0.00039 20.3 0.0 0.00079 19.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EEQ29489.1 - 0.0015 17.8 0.1 0.0047 16.2 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 EEQ29489.1 - 0.0022 17.4 0.0 0.0052 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ29489.1 - 0.0065 16.6 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEQ29489.1 - 0.0069 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EEQ29489.1 - 0.0078 15.0 0.0 0.16 10.7 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.9 EEQ29489.1 - 0.0085 15.8 0.0 0.22 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 EEQ29489.1 - 0.009 15.5 0.1 0.029 13.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.1 EEQ29489.1 - 0.0091 16.0 0.2 0.032 14.2 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EEQ29489.1 - 0.016 14.9 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EEQ29489.1 - 0.02 14.0 0.0 0.05 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EEQ29489.1 - 0.039 12.9 0.6 0.089 11.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 EEQ29489.1 - 0.041 12.7 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PIF1 PF05970.9 EEQ29489.1 - 0.062 12.2 0.0 5 5.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase UvrD_C_2 PF13538.1 EEQ29489.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Strep_SA_rep PF06696.6 EEQ29489.1 - 0.16 11.7 0.2 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Streptococcal surface antigen repeat cobW PF02492.14 EEQ29489.1 - 0.24 10.8 0.0 0.49 9.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain 4HBT PF03061.17 EEQ29490.1 - 7.4e-14 51.6 0.2 1.1e-13 51.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EEQ29490.1 - 0.04 13.6 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Transp_cyt_pur PF02133.10 EEQ29491.1 - 1.9e-91 306.8 35.6 1.9e-91 306.8 24.7 1.4 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Tfb2 PF03849.9 EEQ29492.1 - 2.6e-137 457.3 0.0 4.6e-137 456.5 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EEQ29492.1 - 2e-05 24.3 0.0 6.6e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 EEQ29492.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Anti-repressor SinI TRAM PF01938.15 EEQ29493.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 TRAM domain PhzC-PhzF PF02567.11 EEQ29494.1 - 2.2e-44 151.7 0.1 5.4e-44 150.4 0.1 1.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein TIMELESS PF04821.9 EEQ29495.1 - 1.8e-91 306.0 0.0 5.9e-91 304.4 0.0 1.9 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 EEQ29495.1 - 1.2e-44 153.2 23.5 2.4e-43 148.9 8.4 4.1 2 1 0 2 2 2 1 Timeless protein C terminal region 3HCDH_N PF02737.13 EEQ29496.1 - 9e-52 175.3 0.6 1.2e-51 174.9 0.4 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EEQ29496.1 - 1.9e-34 117.9 0.0 4.4e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EEQ29496.1 - 0.0002 21.2 0.7 0.0004 20.2 0.2 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EEQ29496.1 - 0.00057 19.3 0.1 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EEQ29496.1 - 0.0016 18.1 0.1 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 EEQ29496.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEQ29496.1 - 0.022 15.1 0.2 0.054 13.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EEQ29496.1 - 0.043 12.9 0.8 0.37 9.9 0.5 2.1 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EEQ29496.1 - 0.13 12.3 0.5 0.28 11.2 0.3 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IBR PF01485.16 EEQ29497.1 - 9.1e-07 28.6 8.9 9.1e-07 28.6 6.2 3.2 3 0 0 3 3 3 1 IBR domain zf-RING_2 PF13639.1 EEQ29497.1 - 0.043 13.6 17.6 0.039 13.7 3.4 2.7 2 0 0 2 2 2 0 Ring finger domain Actin PF00022.14 EEQ29500.1 - 1.5e-104 349.5 0.0 1.9e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEQ29500.1 - 0.15 10.6 0.0 1.4 7.3 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein ADH_N PF08240.7 EEQ29501.1 - 2.9e-29 101.0 1.0 4.8e-29 100.3 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ29501.1 - 1.6e-25 89.1 0.9 1.8e-25 88.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ29501.1 - 0.017 16.0 0.0 0.038 14.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEQ29501.1 - 0.08 12.0 0.2 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GCIP PF13324.1 EEQ29502.1 - 3.9e-09 36.1 0.7 5.1e-09 35.7 0.5 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.8 EEQ29502.1 - 0.034 13.7 2.5 0.06 12.9 1.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region LRR_4 PF12799.2 EEQ29503.1 - 2.6e-32 109.8 48.9 3.1e-09 36.2 1.4 10.9 7 3 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ29503.1 - 2.7e-29 100.6 42.9 2.5e-09 36.7 1.6 8.9 6 3 2 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 EEQ29503.1 - 2e-17 60.5 36.9 0.18 11.9 0.0 16.5 17 1 1 18 18 18 5 Leucine Rich Repeat LRR_7 PF13504.1 EEQ29503.1 - 6.5e-14 49.6 42.1 0.14 12.4 0.1 15.9 18 0 0 18 18 18 5 Leucine rich repeat LRR_6 PF13516.1 EEQ29503.1 - 5.5e-06 25.9 33.5 6.5 7.1 0.0 12.9 15 0 0 15 15 15 2 Leucine Rich repeat TMF_TATA_bd PF12325.3 EEQ29504.1 - 0.017 14.8 9.3 0.031 13.9 6.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mto2_bdg PF12808.2 EEQ29504.1 - 0.19 11.8 6.0 0.2 11.7 1.2 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PspB PF06667.7 EEQ29504.1 - 0.42 10.5 1.5 26 4.8 0.0 2.8 2 1 1 3 3 3 0 Phage shock protein B IncA PF04156.9 EEQ29504.1 - 0.44 10.1 9.5 0.98 8.9 6.6 1.5 1 0 0 1 1 1 0 IncA protein GrpE PF01025.14 EEQ29504.1 - 0.64 9.5 6.8 5.8 6.4 1.2 2.3 2 0 0 2 2 2 0 GrpE Atg14 PF10186.4 EEQ29504.1 - 0.68 8.8 12.3 1.3 7.9 8.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L13e PF01294.13 EEQ29505.1 - 4.4e-64 215.2 3.0 5.9e-64 214.8 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF501 PF04417.7 EEQ29506.1 - 0.0029 17.4 0.3 0.0083 15.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF501) DUF4635 PF15466.1 EEQ29506.1 - 1.1 8.5 4.2 3.4 6.9 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Oxidored-like PF09791.4 EEQ29507.1 - 8.8e-26 89.1 4.9 8.8e-26 89.1 3.4 2.2 3 0 0 3 3 3 1 Oxidoreductase-like protein, N-terminal vMSA PF00695.14 EEQ29507.1 - 6.8 5.7 5.6 9.7 5.2 3.9 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus KAP PF05804.7 EEQ29508.1 - 0.00019 19.5 0.0 0.0011 16.9 0.0 1.9 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Arm PF00514.18 EEQ29508.1 - 0.18 11.6 2.5 27 4.7 0.1 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat F-box-like PF12937.2 EEQ29509.1 - 0.00021 20.9 2.1 0.00049 19.7 1.5 1.7 1 0 0 1 1 1 1 F-box-like DPM3 PF08285.6 EEQ29512.1 - 2.2e-29 101.1 0.4 2.4e-29 100.9 0.3 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Yip1 PF04893.12 EEQ29512.1 - 0.064 12.7 2.2 0.082 12.4 1.5 1.1 1 0 0 1 1 1 0 Yip1 domain Pribosyltran PF00156.22 EEQ29513.1 - 4.5e-09 36.0 0.1 1.5e-08 34.3 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain HSF_DNA-bind PF00447.12 EEQ29515.1 - 4.2e-10 39.7 0.0 2.1e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding DUF3245 PF11595.3 EEQ29516.1 - 2.5e-40 138.2 7.1 3.4e-40 137.7 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) ATP-grasp_2 PF08442.5 EEQ29517.1 - 1.5e-78 262.8 0.2 2.4e-78 262.1 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EEQ29517.1 - 5e-25 87.8 0.6 1.6e-24 86.2 0.2 1.9 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EEQ29517.1 - 1.1e-08 34.6 0.2 2.4e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EEQ29517.1 - 0.00022 20.8 1.3 0.046 13.2 0.1 2.6 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.1 EEQ29517.1 - 0.0028 17.2 0.3 0.86 9.2 0.0 2.6 1 1 1 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 EEQ29517.1 - 0.038 13.7 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EEQ29517.1 - 0.059 12.8 0.0 0.72 9.2 0.0 2.5 2 1 1 3 3 3 0 RimK-like ATP-grasp domain adh_short PF00106.20 EEQ29518.1 - 3.7e-18 66.0 0.0 5.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ29518.1 - 1.6e-10 41.2 0.0 1.9e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEQ29518.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Antitoxin-MazE PF04014.13 EEQ29519.1 - 0.13 11.9 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Antidote-toxin recognition MazE DUF2841 PF11001.3 EEQ29520.1 - 3.1e-45 153.0 0.2 4.4e-45 152.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Dicty_REP PF05086.7 EEQ29524.1 - 0.38 8.4 3.1 0.52 7.9 2.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Beta-lactamase PF00144.19 EEQ29525.1 - 3.9e-40 137.8 0.0 5.5e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EEQ29525.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Peptidase_S8 PF00082.17 EEQ29526.1 - 2.5e-42 144.9 13.5 3.3e-42 144.5 9.4 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ29526.1 - 2.7e-18 66.3 0.1 4.6e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 GARS_C PF02843.11 EEQ29526.1 - 0.055 13.6 0.8 2.8 8.1 0.0 2.7 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain DUF4090 PF13319.1 EEQ29526.1 - 0.074 13.0 0.4 0.38 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) SLAC1 PF03595.12 EEQ29528.1 - 2.7e-75 253.0 52.5 3.1e-75 252.8 36.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TraP PF07296.6 EEQ29528.1 - 8 5.3 5.7 0.52 9.2 0.2 1.6 2 0 0 2 2 2 0 TraP protein ABC1 PF03109.11 EEQ29529.1 - 9e-23 80.5 0.0 2.5e-13 50.0 0.0 2.5 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.17 EEQ29529.1 - 0.012 14.9 0.0 0.03 13.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DUF2238 PF09997.4 EEQ29529.1 - 0.096 12.0 0.3 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) HA2 PF04408.18 EEQ29530.1 - 1.7e-15 56.8 0.0 1.5e-14 53.8 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ29530.1 - 1.8e-06 27.7 0.0 6e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ29530.1 - 0.0012 18.3 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEQ29530.1 - 0.017 15.2 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EEQ29530.1 - 0.028 13.3 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 EEQ29530.1 - 0.029 14.8 0.1 0.13 12.7 0.0 2.1 2 0 0 2 2 1 0 Miro-like protein AAA_19 PF13245.1 EEQ29530.1 - 0.033 13.9 0.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain PhoH PF02562.11 EEQ29530.1 - 0.037 13.2 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF258 PF03193.11 EEQ29530.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EEQ29530.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase OAR PF03826.12 EEQ29530.1 - 1.5 8.4 5.8 17 5.0 1.0 2.7 2 0 0 2 2 2 0 OAR domain SSB PF00436.20 EEQ29531.1 - 3.1e-14 52.7 0.0 4.6e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.10 EEQ29532.1 - 3e-73 246.3 25.0 8.8e-56 189.0 7.7 3.1 2 1 1 3 3 3 3 Pheromone A receptor Pex24p PF06398.6 EEQ29532.1 - 0.01 14.6 0.6 0.018 13.8 0.4 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Exo_endo_phos PF03372.18 EEQ29535.1 - 1.9e-19 70.6 0.1 2.9e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.8 EEQ29536.1 - 1.7e-17 63.6 0.0 9.8e-17 61.1 0.0 1.9 1 1 0 1 1 1 1 Dcp1-like decapping family DUF2305 PF10230.4 EEQ29537.1 - 3.5e-71 239.7 0.0 4.3e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EEQ29537.1 - 2.1e-06 27.8 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ29537.1 - 2.5e-05 24.0 0.0 8.7e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EEQ29537.1 - 5.9e-05 23.4 1.4 0.0003 21.1 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_3 PF07859.8 EEQ29537.1 - 0.003 17.1 0.0 0.0072 15.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EEQ29537.1 - 0.0057 16.2 0.0 0.092 12.3 0.0 2.3 1 1 1 2 2 2 1 Lipase (class 3) DUF3089 PF11288.3 EEQ29537.1 - 0.019 14.1 0.1 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DLH PF01738.13 EEQ29537.1 - 0.022 14.0 0.0 6.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF1910 PF08928.5 EEQ29537.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) PGAP1 PF07819.8 EEQ29537.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein ATP_synt_I PF03899.10 EEQ29537.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 ATP synthase I chain FSH1 PF03959.8 EEQ29537.1 - 0.12 11.8 0.0 6.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Ebola_NP PF05505.7 EEQ29538.1 - 2.6 5.9 12.9 8.3 4.3 8.7 1.8 2 0 0 2 2 2 0 Ebola nucleoprotein SMK-1 PF04802.10 EEQ29539.1 - 3.4e-34 118.0 0.1 4.5e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF914 PF06027.7 EEQ29541.1 - 7.6e-103 343.8 22.7 9.6e-103 343.5 15.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EEQ29541.1 - 0.0013 18.7 12.3 0.0013 18.7 8.6 2.6 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 EEQ29541.1 - 0.078 12.6 28.2 0.37 10.4 3.0 2.9 2 1 0 3 3 3 0 Triose-phosphate Transporter family PAP_assoc PF03828.14 EEQ29544.1 - 5.2e-17 61.5 0.1 1.3e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEQ29544.1 - 1.7e-05 25.0 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain SE PF08491.5 EEQ29546.1 - 1.5e-77 260.1 0.0 2.1e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EEQ29546.1 - 1.9e-09 37.0 0.0 2.2e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EEQ29546.1 - 2.8e-09 36.3 0.3 7.6e-07 28.3 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ29546.1 - 4.1e-07 29.2 1.1 3e-06 26.3 0.5 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EEQ29546.1 - 1.9e-05 24.6 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ29546.1 - 0.00023 21.1 0.4 0.00055 19.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EEQ29546.1 - 0.00025 19.6 0.5 0.00049 18.6 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EEQ29546.1 - 0.00026 20.1 0.2 0.00029 20.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EEQ29546.1 - 0.00071 18.5 0.1 0.001 17.9 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EEQ29546.1 - 0.00075 19.8 0.1 0.0035 17.7 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ29546.1 - 0.0024 17.0 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEQ29546.1 - 0.0028 16.6 0.2 0.0051 15.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EEQ29546.1 - 0.011 14.4 0.2 0.017 13.7 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GDI PF00996.13 EEQ29546.1 - 0.66 8.2 2.0 0.37 9.0 0.0 1.5 2 0 0 2 2 2 0 GDP dissociation inhibitor PPR PF01535.15 EEQ29547.1 - 1.4e-05 24.7 1.2 0.17 11.9 0.0 5.7 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.1 EEQ29547.1 - 1.5e-05 24.8 1.4 0.0027 17.8 0.0 5.2 6 0 0 6 6 6 1 Pentatricopeptide repeat domain TPR_19 PF14559.1 EEQ29547.1 - 0.00039 20.6 0.5 0.75 10.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_2 PF13041.1 EEQ29547.1 - 0.0017 18.2 1.0 1.3 9.0 0.0 4.6 5 0 0 5 5 5 1 PPR repeat family PPR_1 PF12854.2 EEQ29547.1 - 0.13 11.7 0.0 22 4.6 0.0 3.1 3 0 0 3 3 3 0 PPR repeat MFS_1 PF07690.11 EEQ29548.1 - 5.5e-25 87.8 14.4 8.3e-25 87.2 9.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 EEQ29548.1 - 0.008 14.7 16.4 0.0039 15.7 4.4 2.8 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like Ferrochelatase PF00762.14 EEQ29549.1 - 3e-91 305.6 0.0 3.5e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku_N PF03731.10 EEQ29550.1 - 1.7e-29 102.8 0.0 2.3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EEQ29550.1 - 2.9e-20 72.5 0.0 3.5e-17 62.4 0.0 2.8 2 1 1 3 3 3 2 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 EEQ29550.1 - 9.5e-15 54.9 0.3 2.8e-14 53.4 0.2 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Adap_comp_sub PF00928.16 EEQ29551.1 - 3.7e-83 278.6 0.0 4.8e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEQ29551.1 - 0.00032 20.4 0.2 0.00054 19.7 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain p450 PF00067.17 EEQ29552.1 - 4.6e-51 173.7 0.0 6.5e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Erf4 PF10256.4 EEQ29553.1 - 3.3e-34 117.2 0.0 4.9e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Abhydrolase_6 PF12697.2 EEQ29554.1 - 0.0023 17.8 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EEQ29554.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.3 EEQ29554.1 - 0.093 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.8 EEQ29554.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.6 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 EEQ29554.1 - 0.12 12.0 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 EEQ29554.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) zf-C2H2 PF00096.21 EEQ29555.1 - 1.1e-17 63.1 47.7 0.0025 18.0 0.5 7.3 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-met PF12874.2 EEQ29555.1 - 3.8e-17 61.8 42.8 1.8e-07 31.1 1.4 6.7 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ29555.1 - 1.3e-16 60.2 40.0 2.1e-07 30.8 1.6 7.1 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EEQ29555.1 - 9.9e-15 53.7 42.9 0.003 17.7 1.1 7.4 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EEQ29555.1 - 2.4e-13 50.0 37.0 0.0027 17.7 0.4 7.1 2 2 5 7 7 7 5 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EEQ29555.1 - 9.8e-08 31.9 29.2 0.17 12.2 0.7 7.4 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 EEQ29555.1 - 0.014 15.2 5.3 0.06 13.2 1.0 7.1 8 0 0 8 8 8 0 C2H2-type zinc finger zf-Di19 PF05605.7 EEQ29555.1 - 0.1 12.7 0.2 0.1 12.7 0.1 5.3 4 2 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Cyto_heme_lyase PF01265.12 EEQ29556.1 - 2.3e-79 266.6 0.0 2.7e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase UQ_con PF00179.21 EEQ29558.1 - 5e-25 87.5 0.1 6.8e-25 87.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 EEQ29559.1 - 4.3e-38 131.5 0.0 6.1e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.12 EEQ29560.1 - 7.3e-07 28.8 12.7 8.5e-05 22.1 5.2 2.3 2 0 0 2 2 2 2 Yip1 domain UFD1 PF03152.9 EEQ29563.1 - 3.3e-28 98.0 0.0 1.6e-24 86.0 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 UBA PF00627.26 EEQ29563.1 - 0.043 13.6 1.1 0.091 12.6 0.0 2.1 3 0 0 3 3 3 0 UBA/TS-N domain zf-DNA_Pol PF08996.5 EEQ29563.1 - 0.14 11.4 6.3 1.2 8.4 0.3 2.9 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Zn-ribbon_8 PF09723.5 EEQ29563.1 - 0.27 11.2 8.2 1 9.3 0.3 4.1 4 0 0 4 4 4 0 Zinc ribbon domain DPPIV_N PF00930.16 EEQ29564.1 - 5.7e-110 367.2 5.0 9.2e-110 366.5 3.5 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EEQ29564.1 - 1.4e-35 122.4 2.4 2.4e-35 121.7 1.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ29564.1 - 5.8e-06 26.1 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ29564.1 - 0.0039 17.1 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family MAPEG PF01124.13 EEQ29565.1 - 1.6e-08 34.2 4.3 2.8e-08 33.4 2.9 1.5 1 1 0 1 1 1 1 MAPEG family MARVEL PF01284.18 EEQ29566.1 - 9.4e-07 28.7 12.2 1.3e-06 28.3 8.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain CytB6-F_Fe-S PF08802.5 EEQ29566.1 - 0.087 12.8 0.9 0.087 12.8 0.7 1.9 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit DUF2189 PF09955.4 EEQ29566.1 - 0.39 10.6 11.7 1.4 8.9 0.0 2.5 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) DUF2975 PF11188.3 EEQ29566.1 - 8 6.1 9.9 3.8 7.2 3.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF829 PF05705.9 EEQ29567.1 - 1.1e-50 172.6 0.0 1.3e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Roughex PF06020.6 EEQ29567.1 - 0.084 11.5 0.0 3.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Drosophila roughex protein RNB PF00773.14 EEQ29569.1 - 1.7e-53 182.0 0.0 9.7e-52 176.2 0.0 2.7 2 1 0 2 2 2 1 RNB domain zf-CGNR PF11706.3 EEQ29569.1 - 0.049 13.1 0.6 0.12 11.9 0.4 1.6 1 0 0 1 1 1 0 CGNR zinc finger CTNNBL PF08216.6 EEQ29570.1 - 8.9e-34 115.3 3.6 1.1e-33 115.0 0.2 2.8 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Drf_GBD PF06371.8 EEQ29570.1 - 0.0054 16.1 0.4 0.11 11.8 0.0 2.9 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain DUF4020 PF13212.1 EEQ29570.1 - 0.044 13.3 0.2 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) HEAT_2 PF13646.1 EEQ29570.1 - 0.1 12.8 2.1 1.1 9.5 0.0 3.0 2 1 1 3 3 3 0 HEAT repeats RNA_pol_Rpb2_6 PF00562.23 EEQ29571.1 - 1.4e-123 412.5 0.2 2.8e-123 411.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEQ29571.1 - 1.4e-60 203.6 0.0 2.2e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EEQ29571.1 - 3.1e-47 160.4 0.0 5.2e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EEQ29571.1 - 2.7e-30 104.4 0.0 5.8e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EEQ29571.1 - 3e-24 84.5 0.4 7e-24 83.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EEQ29571.1 - 9.6e-24 83.1 0.3 2.6e-23 81.7 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EEQ29571.1 - 1.1e-22 79.5 0.8 1.8e-22 78.8 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 Nucleopor_Nup85 PF07575.8 EEQ29574.1 - 2e-16 59.3 5.3 3.8e-09 35.3 0.0 3.5 4 0 0 4 4 4 3 Nup85 Nucleoporin PE-PPE PF08237.6 EEQ29574.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain ADH_N PF08240.7 EEQ29576.1 - 1.7e-22 79.2 0.9 2.7e-22 78.5 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ29576.1 - 7.4e-13 48.1 0.1 1.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ29576.1 - 4.2e-07 30.9 0.0 6.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEQ29576.1 - 0.0055 15.8 0.1 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EEQ29576.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TPR_11 PF13414.1 EEQ29577.1 - 1.7e-19 69.2 28.1 1.2e-05 24.8 1.2 7.4 5 1 2 7 7 7 5 TPR repeat TPR_17 PF13431.1 EEQ29577.1 - 7.6e-14 50.6 14.0 0.011 15.9 0.1 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ29577.1 - 2.7e-12 46.8 21.9 0.0008 19.6 0.1 7.4 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ29577.1 - 2.1e-09 37.8 23.6 0.00025 21.6 0.1 8.3 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ29577.1 - 1.4e-07 30.7 29.1 0.26 11.1 0.0 9.6 10 1 1 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ29577.1 - 3.6e-07 30.0 20.8 0.0019 18.1 0.8 7.4 6 2 2 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 EEQ29577.1 - 4.4e-07 29.9 19.0 0.0046 17.0 3.0 5.3 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EEQ29577.1 - 6.7e-07 29.3 23.4 0.16 12.6 0.0 9.3 8 3 3 11 11 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ29577.1 - 8.4e-05 22.2 44.1 0.45 10.5 0.1 10.6 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ29577.1 - 0.00015 21.2 29.7 0.78 9.4 0.1 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_20 PF14561.1 EEQ29577.1 - 0.0045 17.0 1.1 3.8 7.6 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ29577.1 - 0.0048 16.7 4.1 0.31 10.9 0.1 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.4 EEQ29577.1 - 0.019 14.3 3.2 18 4.6 0.2 4.5 3 2 1 4 4 4 0 26S proteasome subunit RPN7 TPR_7 PF13176.1 EEQ29577.1 - 0.029 14.1 17.5 0.34 10.8 0.1 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ29577.1 - 0.053 13.9 4.3 40 5.0 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EEQ29577.1 - 0.056 12.2 0.0 0.097 11.4 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Alkyl_sulf_dimr PF14863.1 EEQ29577.1 - 0.13 12.5 2.6 0.56 10.4 0.0 2.7 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation BTAD PF03704.12 EEQ29577.1 - 0.33 11.2 5.2 0.35 11.1 0.3 2.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain DUF3336 PF11815.3 EEQ29578.1 - 9.5e-47 158.1 0.7 1.5e-46 157.5 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEQ29578.1 - 6.9e-20 71.8 0.4 2e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase LRR_4 PF12799.2 EEQ29579.1 - 2e-19 68.7 6.3 3.3e-06 26.5 0.7 5.8 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEQ29579.1 - 6.7e-12 43.6 9.4 1.2 9.3 0.0 7.5 6 1 1 7 7 7 5 Leucine Rich Repeat LRR_8 PF13855.1 EEQ29579.1 - 9.5e-11 41.2 13.5 1e-06 28.3 1.9 4.4 3 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EEQ29579.1 - 4.4e-06 26.2 9.0 5 7.5 0.0 6.3 6 1 1 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 EEQ29579.1 - 0.00064 19.5 12.5 12 6.6 0.1 6.7 6 1 0 6 6 6 1 Leucine rich repeat Metallophos PF00149.23 EEQ29580.1 - 6.7e-45 152.9 0.2 8.2e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.16 EEQ29581.1 - 5e-64 214.7 0.0 5.6e-64 214.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EEQ29581.1 - 2.6e-09 36.2 0.1 9.4e-06 24.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EEQ29581.1 - 1.3e-08 34.2 0.0 1.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EEQ29581.1 - 3.7e-07 30.6 0.0 4.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ29581.1 - 1.5e-06 28.1 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EEQ29581.1 - 0.00017 21.0 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EEQ29581.1 - 0.0011 18.1 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EEQ29581.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EEQ29581.1 - 0.1 12.0 0.1 4.5 6.6 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF2457 PF10446.4 EEQ29582.1 - 1.3e-134 449.4 31.5 1.3e-134 449.4 21.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 EEQ29582.1 - 0.14 10.2 21.8 0.11 10.5 10.8 2.2 2 0 0 2 2 2 0 CDC45-like protein SAPS PF04499.10 EEQ29582.1 - 1.8 7.1 6.2 2.7 6.5 4.3 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 EEQ29582.1 - 4.4 5.0 38.9 0.13 10.1 20.8 2.1 2 0 0 2 2 2 0 Nop14-like family CH PF00307.26 EEQ29583.1 - 2.2e-07 30.8 0.0 0.0024 17.9 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EEQ29583.1 - 0.00067 19.2 0.0 0.4 10.3 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain Peptidase_M3 PF01432.15 EEQ29583.1 - 0.032 13.2 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M3 Fungal_trans_2 PF11951.3 EEQ29584.1 - 1.5e-08 33.6 0.1 2.8e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ29584.1 - 0.0099 15.7 6.7 0.024 14.5 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PCNA_C PF02747.10 EEQ29585.1 - 5.5e-51 171.8 0.0 1.3e-50 170.5 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EEQ29585.1 - 3.4e-32 110.6 0.7 7.2e-32 109.5 0.5 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 EEQ29585.1 - 0.00027 19.8 0.1 0.00045 19.0 0.1 1.4 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EEQ29585.1 - 0.00052 19.2 0.0 0.00081 18.5 0.0 1.2 1 0 0 1 1 1 1 Rad9 Vezatin PF12632.2 EEQ29585.1 - 0.00095 18.3 0.0 0.0027 16.8 0.0 1.7 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF720 PF05302.6 EEQ29585.1 - 0.071 12.8 0.4 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF720) DUF1129 PF06570.6 EEQ29586.1 - 0.83 8.9 11.7 0.13 11.5 5.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) HemY_N PF07219.8 EEQ29586.1 - 2.4 7.7 5.8 24 4.5 0.0 2.6 2 1 0 2 2 2 0 HemY protein N-terminus Sec61_beta PF03911.11 EEQ29587.1 - 1.1e-19 69.9 0.9 1.4e-19 69.5 0.6 1.2 1 0 0 1 1 1 1 Sec61beta family RecR PF02132.10 EEQ29589.1 - 0.06 12.7 1.0 0.84 9.1 0.1 2.2 2 0 0 2 2 2 0 RecR protein Dynein_light PF01221.13 EEQ29590.1 - 7.4e-39 131.6 2.2 9e-39 131.3 1.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 PFU PF09070.6 EEQ29590.1 - 0.025 14.6 0.2 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Imm28 PF15574.1 EEQ29590.1 - 0.04 13.4 0.2 0.062 12.8 0.1 1.3 1 1 0 1 1 1 0 Immunity protein 28 RRM_1 PF00076.17 EEQ29591.1 - 1.9e-73 242.0 0.2 9.4e-19 66.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ29591.1 - 4.2e-58 193.2 0.1 1.2e-11 44.4 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ29591.1 - 3e-32 110.2 0.0 2.1e-07 30.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEQ29591.1 - 8.4e-09 35.0 0.3 0.6 9.8 0.0 5.5 5 0 0 5 5 5 3 Limkain b1 Nup35_RRM_2 PF14605.1 EEQ29591.1 - 2.9e-05 23.7 0.0 0.23 11.2 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.7 EEQ29591.1 - 0.015 15.2 0.0 3.9 7.5 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif 2 Rota_NS53 PF00981.12 EEQ29591.1 - 0.15 10.6 0.1 0.23 10.0 0.1 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Aldo_ket_red PF00248.16 EEQ29592.1 - 1.4e-50 171.7 0.0 1.7e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_6 PF14259.1 EEQ29593.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ29593.1 - 0.035 13.7 0.1 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GHMP_kinases_C PF08544.8 EEQ29593.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal APH PF01636.18 EEQ29594.1 - 8.1e-12 45.3 0.0 1.2e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ29594.1 - 0.19 10.3 0.1 9.3 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) NIF PF03031.13 EEQ29597.1 - 9.7e-49 165.0 0.6 1.6e-48 164.3 0.4 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.2 EEQ29598.1 - 6.5e-38 127.7 42.1 8.9e-10 37.9 1.4 7.2 5 1 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ29598.1 - 9.9e-30 102.0 83.4 9.9e-08 31.6 4.4 5.5 2 1 7 9 9 9 7 Leucine rich repeat LRR_1 PF00560.28 EEQ29598.1 - 2.2e-12 45.2 36.3 0.36 11.0 0.8 10.8 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_9 PF14580.1 EEQ29598.1 - 6e-12 45.4 14.1 0.00021 20.9 1.0 3.7 1 1 3 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 EEQ29598.1 - 2.1e-11 42.0 18.7 3.1 8.3 0.0 10.0 9 1 0 9 9 9 4 Leucine rich repeat LRR_6 PF13516.1 EEQ29598.1 - 6.4e-11 41.1 28.5 0.29 11.3 0.7 10.0 4 3 5 9 9 9 4 Leucine Rich repeat WHIM3 PF15614.1 EEQ29598.1 - 1.4 8.7 3.9 8.2 6.3 1.1 2.8 2 1 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 ABC_membrane_2 PF06472.10 EEQ29599.1 - 2.8e-94 315.3 0.1 2.8e-94 315.3 0.1 1.7 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EEQ29599.1 - 1.3e-17 64.3 0.0 2.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EEQ29599.1 - 0.00076 18.9 0.0 0.074 12.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EEQ29599.1 - 0.0027 17.7 0.0 0.0074 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ALIX_LYPXL_bnd PF13949.1 EEQ29599.1 - 0.017 14.1 0.2 0.027 13.4 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA_23 PF13476.1 EEQ29599.1 - 0.024 14.9 3.3 0.24 11.7 2.3 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEQ29599.1 - 0.033 14.1 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.16 EEQ29599.1 - 0.04 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EEQ29599.1 - 0.05 13.7 0.8 0.42 10.8 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEQ29599.1 - 0.073 12.8 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain SMC_N PF02463.14 EEQ29599.1 - 0.075 12.2 0.0 3.1 6.9 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Clr2 PF10383.4 EEQ29600.1 - 9e-26 90.5 0.0 1.7e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 2OG-FeII_Oxy PF03171.15 EEQ29601.1 - 0.0019 18.4 0.0 0.004 17.4 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SAD_SRA PF02182.12 EEQ29602.1 - 3.8e-18 65.2 0.0 1.2e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 SAD/SRA domain SLY PF12485.3 EEQ29602.1 - 0.33 11.1 6.7 0.91 9.7 2.8 2.3 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein CLTH PF10607.4 EEQ29603.1 - 7.1e-30 103.6 0.0 1.4e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EEQ29603.1 - 1.2e-15 56.9 1.3 4.9e-15 54.9 0.9 2.2 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EEQ29603.1 - 6.7e-05 22.2 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EEQ29603.1 - 0.0013 18.5 0.6 0.0023 17.7 0.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ29603.1 - 0.0037 17.2 1.1 0.0071 16.3 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ29603.1 - 0.0038 16.8 0.6 0.0067 16.0 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ29603.1 - 0.0055 16.4 0.3 0.011 15.4 0.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEQ29603.1 - 0.2 11.3 0.8 0.43 10.2 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEQ29603.1 - 0.47 10.3 2.5 0.78 9.6 0.8 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PG_binding_1 PF01471.13 EEQ29604.1 - 0.003 17.5 0.8 1 9.4 0.0 3.4 3 0 0 3 3 3 2 Putative peptidoglycan binding domain zf-Tim10_DDP PF02953.10 EEQ29605.1 - 2.5e-23 81.1 2.6 3.2e-23 80.7 1.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF779 PF05610.6 EEQ29605.1 - 0.13 12.3 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF779) Tom5 PF10642.4 EEQ29605.1 - 0.57 9.8 0.1 0.57 9.8 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase tRNA-synt_2 PF00152.15 EEQ29606.1 - 4.5e-81 272.2 0.0 5.4e-81 271.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ29606.1 - 6.2e-09 35.5 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEQ29606.1 - 2.9e-05 23.4 0.0 0.013 14.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EEQ29606.1 - 0.015 14.8 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) BTB PF00651.26 EEQ29607.1 - 1.2e-06 28.4 0.0 5.1e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF2475 PF10629.4 EEQ29607.1 - 0.093 12.9 0.1 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) PCI PF01399.22 EEQ29608.1 - 1.9e-09 37.7 0.0 4.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.9 EEQ29608.1 - 0.02 14.2 0.0 0.051 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Ribosomal_L18ae PF01775.12 EEQ29609.1 - 8.2e-59 196.9 2.6 1.1e-58 196.4 1.8 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DUF1796 PF08795.5 EEQ29609.1 - 0.12 11.9 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) NAD_binding_1 PF00175.16 EEQ29610.1 - 4e-31 107.7 0.0 6.4e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEQ29610.1 - 1.7e-21 76.1 0.0 3.7e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEQ29610.1 - 7.2e-09 35.7 0.0 4.2e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EEQ29610.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain HMG_box PF00505.14 EEQ29611.1 - 2.4e-13 50.1 3.5 5.5e-13 48.9 2.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEQ29611.1 - 8.2e-08 32.5 3.5 2.2e-07 31.1 2.4 1.8 1 0 0 1 1 1 1 HMG-box domain Amidohydro_1 PF01979.15 EEQ29612.1 - 5.3e-65 220.2 0.8 8.3e-65 219.6 0.5 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EEQ29612.1 - 8.4e-54 180.8 1.4 2.1e-53 179.5 1.0 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EEQ29612.1 - 1.2e-40 137.3 0.5 1.4e-39 133.9 0.1 2.2 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EEQ29612.1 - 5.2e-37 125.8 0.1 1e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.6 EEQ29612.1 - 2.7e-05 23.5 0.2 0.0016 17.7 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EEQ29612.1 - 5.6e-05 22.8 4.8 0.00017 21.3 3.3 1.9 1 0 0 1 1 1 1 Amidohydrolase Lactamase_B_2 PF12706.2 EEQ29613.1 - 7e-09 35.5 0.0 2.5e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EEQ29613.1 - 9.1e-06 25.6 0.0 4.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 EEQ29613.1 - 0.00088 18.9 0.2 0.0036 16.9 0.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF1799 PF08809.6 EEQ29614.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) NPR2 PF06218.6 EEQ29615.1 - 4.7e-130 434.1 0.0 8.2e-130 433.3 0.0 1.3 2 0 0 2 2 2 1 Nitrogen permease regulator 2 NPR3 PF03666.8 EEQ29615.1 - 0.008 14.7 0.0 2.5 6.5 0.0 2.2 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 Ada3 PF10198.4 EEQ29616.1 - 3.2e-43 146.6 0.6 6e-43 145.7 0.0 1.8 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.1 EEQ29618.1 - 4.1e-12 45.7 8.2 7.7e-12 44.8 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ29618.1 - 1.9e-06 27.5 3.2 3.2e-06 26.7 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ29618.1 - 2.2e-06 27.5 5.0 4.3e-06 26.6 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ29618.1 - 4.8e-06 26.1 3.8 8.5e-06 25.3 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ29618.1 - 1.2e-05 25.3 2.3 2.5e-05 24.2 1.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EEQ29618.1 - 0.00012 21.6 5.1 0.00022 20.8 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ29618.1 - 0.006 16.3 2.3 0.016 15.0 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EEQ29618.1 - 0.02 14.5 1.3 0.042 13.5 0.2 2.1 1 1 1 2 2 2 0 RING-type zinc-finger DUF1049 PF06305.6 EEQ29618.1 - 0.064 12.7 1.8 0.14 11.6 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) zf-P11 PF03854.9 EEQ29618.1 - 8.4 5.9 7.3 0.48 9.9 1.0 1.9 2 0 0 2 2 2 0 P-11 zinc finger HemY_N PF07219.8 EEQ29618.1 - 9.5 5.8 7.2 5.3 6.6 1.3 2.2 2 0 0 2 2 2 0 HemY protein N-terminus FRG1 PF06229.7 EEQ29619.1 - 4.7e-59 199.0 0.0 6.5e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EEQ29619.1 - 0.042 13.9 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Fascin domain ADH_N PF08240.7 EEQ29620.1 - 1.3e-35 121.3 3.7 2.7e-35 120.4 2.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ29620.1 - 3.1e-15 55.8 0.0 4.8e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ29620.1 - 6.9e-05 23.7 0.0 0.00012 22.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EEQ29620.1 - 0.0057 16.8 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Methyltransf_18 PF12847.2 EEQ29620.1 - 0.0063 17.0 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Gp_dh_N PF00044.19 EEQ29620.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EEQ29620.1 - 0.035 13.1 0.2 0.056 12.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Saccharop_dh PF03435.13 EEQ29620.1 - 0.044 12.7 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADH_4Fe-4S PF10589.4 EEQ29620.1 - 0.14 11.3 1.1 0.47 9.6 0.8 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ThiF PF00899.16 EEQ29620.1 - 0.16 11.8 0.5 14 5.4 0.0 2.3 1 1 1 2 2 2 0 ThiF family HECT PF00632.20 EEQ29621.1 - 7.5e-72 242.1 0.0 1.1e-71 241.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L15e PF00827.12 EEQ29622.1 - 5.1e-88 293.6 7.8 9.5e-88 292.7 5.4 1.4 1 1 0 1 1 1 1 Ribosomal L15 Cep57_CLD PF14073.1 EEQ29623.1 - 0.048 13.4 6.3 1.1 9.1 1.4 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 WD40 PF00400.27 EEQ29624.1 - 4.5e-38 127.7 8.6 1.9e-09 37.0 0.3 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EEQ29624.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain EF-hand_1 PF00036.27 EEQ29625.1 - 1.3e-12 46.0 8.6 1.3e-06 27.2 0.3 3.7 4 0 0 4 4 4 2 EF hand ZZ PF00569.12 EEQ29625.1 - 1.5e-11 43.6 4.4 3.6e-11 42.4 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.1 EEQ29625.1 - 4.4e-11 42.7 2.5 2.1e-10 40.5 1.3 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ29625.1 - 1.5e-08 33.8 7.3 0.00082 19.0 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EEQ29625.1 - 7.7e-07 28.6 3.8 0.0014 18.2 0.3 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EEQ29625.1 - 3.3e-06 26.1 6.9 0.005 16.1 0.2 3.6 3 0 0 3 3 3 2 EF hand Nop25 PF09805.4 EEQ29625.1 - 5.1 7.1 14.6 7.5 6.6 3.3 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) HTH_29 PF13551.1 EEQ29626.1 - 3.5e-08 33.5 0.0 6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EEQ29626.1 - 2.1e-05 24.0 0.0 4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EEQ29626.1 - 0.00012 21.9 0.0 0.00033 20.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.10 EEQ29626.1 - 0.00013 21.7 0.1 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DUF2774 PF11242.3 EEQ29626.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEQ29626.1 - 0.0012 18.2 0.0 0.088 12.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.1 EEQ29626.1 - 0.0018 17.7 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EEQ29626.1 - 0.0034 17.3 0.0 0.12 12.4 0.0 2.6 3 0 0 3 3 3 1 Transposase HTH_32 PF13565.1 EEQ29626.1 - 0.017 15.9 0.0 0.073 13.8 0.0 1.9 1 1 1 2 2 2 0 Homeodomain-like domain Reo_sigmaC PF04582.7 EEQ29628.1 - 0.43 9.7 18.2 0.031 13.4 2.5 3.3 1 1 1 3 3 3 0 Reovirus sigma C capsid protein TPP1 PF10341.4 EEQ29629.1 - 2.6e-16 59.5 0.0 5.4e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD PIP5K PF01504.13 EEQ29630.1 - 5.1e-62 209.2 0.6 9.6e-62 208.3 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EEQ29630.1 - 7e-29 100.7 0.0 1.1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EEQ29630.1 - 5e-15 55.1 4.3 5e-15 55.1 3.0 2.0 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.17 EEQ29630.1 - 0.0077 15.9 2.5 0.021 14.5 1.7 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3391 PF11871.3 EEQ29630.1 - 0.026 14.7 0.5 0.78 9.9 0.1 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Ribosomal_S8 PF00410.14 EEQ29632.1 - 8.5e-25 87.0 0.0 1.5e-24 86.2 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 Sugar_tr PF00083.19 EEQ29633.1 - 4.6e-79 266.0 25.2 5.5e-79 265.8 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ29633.1 - 4.3e-15 55.2 31.0 3.6e-11 42.3 7.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EEQ29635.1 - 1.6e-14 53.7 0.2 8.4e-13 48.0 0.1 3.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEQ29635.1 - 0.00056 19.8 0.0 0.0051 16.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ29635.1 - 0.00065 18.7 0.1 0.0016 17.3 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EEQ29635.1 - 0.001 18.2 0.8 0.045 12.8 0.2 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ29635.1 - 0.0014 18.6 0.1 0.0064 16.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EEQ29635.1 - 0.0025 16.3 0.0 0.0042 15.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EEQ29635.1 - 0.0045 17.3 0.0 0.074 13.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEQ29635.1 - 0.014 14.2 0.0 0.035 12.9 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A SE PF08491.5 EEQ29635.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Diacid_rec PF05651.8 EEQ29635.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative sugar diacid recognition Sdh_cyt PF01127.17 EEQ29636.1 - 1.5e-23 82.8 3.7 2.6e-23 82.1 2.5 1.4 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Peptidase_M24 PF00557.19 EEQ29637.1 - 3.8e-45 154.0 0.0 4.6e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EEQ29637.1 - 0.023 14.5 9.4 0.023 14.5 6.5 2.2 2 0 0 2 2 2 0 MYND finger MFS_1 PF07690.11 EEQ29638.1 - 2.9e-42 144.6 46.0 2.9e-42 144.6 31.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ29638.1 - 1.1e-11 44.0 8.5 1.1e-11 44.0 5.9 3.5 1 1 2 4 4 4 2 Sugar (and other) transporter Acyl_transf_3 PF01757.17 EEQ29638.1 - 0.018 13.8 25.7 0.085 11.6 6.6 2.5 1 1 1 2 2 2 0 Acyltransferase family Zn_clus PF00172.13 EEQ29639.1 - 3.1e-07 30.1 10.3 5.3e-07 29.4 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG-CoA_red PF00368.13 EEQ29640.1 - 7e-152 505.4 3.8 8.7e-152 505.1 2.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase polyprenyl_synt PF00348.12 EEQ29641.1 - 3.5e-49 167.0 0.0 4.4e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HMG_CoA_synt_C PF08540.5 EEQ29642.1 - 4.1e-90 302.0 0.3 5.5e-90 301.6 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EEQ29642.1 - 1.4e-88 295.0 0.0 1.9e-88 294.5 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal GST_C PF00043.20 EEQ29643.1 - 3.3e-12 46.2 0.0 6.9e-12 45.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ29643.1 - 3.5e-11 43.1 0.0 5.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEQ29643.1 - 1.5e-10 41.1 0.0 3.5e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ29643.1 - 6.7e-10 38.7 0.3 1.6e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ29643.1 - 0.0001 22.7 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEQ29643.1 - 0.0049 16.8 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AHSP PF09236.5 EEQ29643.1 - 0.097 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein Prenyltrans_2 PF13249.1 EEQ29644.1 - 2.2e-09 37.7 0.0 0.088 13.2 0.0 4.4 3 1 0 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEQ29644.1 - 0.00074 19.4 0.0 0.14 12.2 0.0 3.5 4 0 0 4 4 4 1 Prenyltransferase-like Prenyltrans PF00432.16 EEQ29644.1 - 0.031 13.8 0.6 3.2 7.3 0.0 3.1 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat adh_short PF00106.20 EEQ29645.1 - 5e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEQ29645.1 - 6.7e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EEQ29645.1 - 0.036 13.0 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase zf-C2H2 PF00096.21 EEQ29647.1 - 0.00052 20.1 8.6 0.07 13.4 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 EEQ29647.1 - 0.0014 18.7 3.0 0.0089 16.2 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EEQ29647.1 - 0.0029 17.8 7.7 0.11 12.8 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ29647.1 - 0.0056 16.7 3.3 0.48 10.6 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EEQ29647.1 - 0.081 13.2 0.1 0.081 13.2 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double domain Spore-coat_CotD PF11122.3 EEQ29647.1 - 0.081 13.2 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Inner spore coat protein D PyrI_C PF02748.10 EEQ29647.1 - 0.12 11.8 1.2 0.2 11.1 0.9 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 EEQ29647.1 - 0.12 12.2 3.4 2.8 7.9 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger p450 PF00067.17 EEQ29648.1 - 1e-42 146.2 0.0 1.3e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1769 PF08588.5 EEQ29649.1 - 1.1e-26 92.4 0.2 2.5e-26 91.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.15 EEQ29650.1 - 3.9e-96 322.0 0.0 2.2e-95 319.5 0.0 1.8 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.9 EEQ29650.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PK PF00224.16 EEQ29652.1 - 1.7e-172 572.8 4.4 2.2e-172 572.4 3.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EEQ29652.1 - 3.3e-31 107.2 0.0 9.4e-31 105.7 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EEQ29652.1 - 0.00014 20.8 0.8 0.00039 19.3 0.5 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EEQ29652.1 - 0.0029 16.5 0.1 0.05 12.4 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.5 EEQ29653.1 - 1.1e-16 60.2 0.0 1.2e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) SUR7 PF06687.7 EEQ29654.1 - 1.3e-40 139.2 4.1 1.5e-40 138.9 2.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Ribosomal_S17 PF00366.15 EEQ29656.1 - 4e-30 103.6 0.9 5.8e-30 103.1 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 EEQ29657.1 - 3.4e-301 1001.6 33.8 5.3e-301 1001.0 23.4 1.3 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EEQ29657.1 - 2.7e-107 358.2 3.0 2.7e-107 358.2 2.1 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EEQ29657.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Spc7_C2 Pil1 PF13805.1 EEQ29658.1 - 3.2e-154 511.8 0.2 4e-154 511.5 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EEQ29658.1 - 0.04 13.2 1.4 0.077 12.3 0.6 1.6 1 1 0 1 1 1 0 FAM92 protein XPG_N PF00752.12 EEQ29659.1 - 2.7e-35 120.6 0.0 1.5e-34 118.2 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EEQ29659.1 - 1.9e-24 85.5 0.0 5.1e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EEQ29659.1 - 9e-05 22.6 0.0 0.00032 20.8 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 EEQ29659.1 - 0.033 14.3 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Transposase_20 PF02371.11 EEQ29659.1 - 0.035 14.2 0.0 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family WD40 PF00400.27 EEQ29660.1 - 7.6e-14 50.9 11.3 1.9e-10 40.1 0.2 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ORC4_C PF14629.1 EEQ29660.1 - 0.035 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus WD40 PF00400.27 EEQ29661.1 - 5.3e-08 32.4 0.3 0.14 12.1 0.0 4.1 3 1 0 3 3 3 3 WD domain, G-beta repeat LSM PF01423.17 EEQ29662.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.6 1 1 0 1 1 1 0 LSM domain Metallophos PF00149.23 EEQ29663.1 - 3e-40 137.7 0.3 3.9e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_fiss_reg PF05308.6 EEQ29663.1 - 0.1 11.9 4.5 0.16 11.3 3.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator WD40 PF00400.27 EEQ29664.1 - 9.1e-25 85.6 8.2 3.5e-06 26.6 0.0 7.4 7 1 1 8 8 8 4 WD domain, G-beta repeat HIRA_B PF09453.5 EEQ29664.1 - 0.00023 20.6 0.5 0.0009 18.7 0.4 2.1 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.6 EEQ29664.1 - 0.0036 17.0 0.1 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EEQ29664.1 - 0.022 14.4 2.1 6.4 6.5 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat F-box-like PF12937.2 EEQ29667.1 - 0.037 13.7 0.1 0.074 12.7 0.1 1.5 1 0 0 1 1 1 0 F-box-like Grp1_Fun34_YaaH PF01184.14 EEQ29668.1 - 1.5e-72 243.2 15.1 1.9e-72 242.9 10.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family HXXEE PF13787.1 EEQ29668.1 - 0.31 11.4 6.4 0.15 12.4 2.8 1.7 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif ANTH PF07651.11 EEQ29669.1 - 1.5e-57 194.4 0.1 2.2e-57 193.9 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EEQ29669.1 - 2.9e-10 40.0 0.0 2e-09 37.3 0.0 2.4 2 1 0 2 2 2 1 ENTH domain TMEM237 PF15383.1 EEQ29669.1 - 1.3 8.0 5.1 2.6 7.0 3.6 1.5 1 0 0 1 1 1 0 Transmembrane protein 237 Memo PF01875.12 EEQ29671.1 - 2.5e-62 210.2 0.0 3e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Rad4 PF03835.10 EEQ29672.1 - 5.3e-16 58.3 5.3 9.2e-16 57.5 3.6 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EEQ29672.1 - 2.2e-13 50.4 0.7 4.9e-13 49.2 0.5 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF3772 PF12607.3 EEQ29672.1 - 7.4 6.3 8.4 0.71 9.5 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) F-box PF00646.28 EEQ29673.1 - 0.16 11.6 0.8 0.54 9.9 0.2 2.1 2 0 0 2 2 2 0 F-box domain WD40 PF00400.27 EEQ29674.1 - 1.6e-17 62.6 8.2 0.0025 17.6 0.0 8.7 9 0 0 9 9 9 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EEQ29674.1 - 2.1e-06 27.4 2.3 1e-05 25.1 0.8 2.6 2 1 0 2 2 2 1 PQQ-like domain Lactonase PF10282.4 EEQ29674.1 - 0.0026 16.9 0.0 0.027 13.5 0.0 2.2 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.1 EEQ29674.1 - 0.32 11.3 2.0 2e+02 2.4 0.1 4.8 5 0 0 5 5 5 0 PQQ-like domain Cyclin_N PF00134.18 EEQ29678.1 - 2.2e-24 85.4 0.1 9.3e-24 83.4 0.1 2.1 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEQ29678.1 - 4.1e-11 42.8 1.8 1.9e-10 40.6 1.3 2.1 1 1 0 1 1 1 1 Cyclin, C-terminal domain Acyl_transf_3 PF01757.17 EEQ29679.1 - 9.8e-26 90.3 24.7 1.5e-25 89.7 17.1 1.3 1 1 0 1 1 1 1 Acyltransferase family Pyr_redox_2 PF07992.9 EEQ29680.1 - 4.1e-15 56.1 0.0 5.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ29680.1 - 0.00099 18.9 0.3 0.53 10.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEQ29680.1 - 0.0032 17.5 0.6 0.81 9.7 0.1 3.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ29680.1 - 0.014 14.3 0.0 0.3 9.9 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEQ29680.1 - 0.063 13.3 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EEQ29680.1 - 0.068 12.2 0.5 0.2 10.6 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 EEQ29680.1 - 0.069 12.0 1.4 1.4 7.6 0.2 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Tub PF01167.13 EEQ29680.1 - 0.076 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Tub family HI0933_like PF03486.9 EEQ29680.1 - 0.11 10.9 0.0 0.31 9.4 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Peptidase_C42 PF05533.7 EEQ29682.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 FKBP_C PF00254.23 EEQ29683.1 - 3e-31 107.3 0.0 3.7e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.23 EEQ29684.1 - 5.3e-16 58.1 0.0 7.8e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zip PF02535.17 EEQ29685.1 - 2.1e-56 191.2 9.6 2.4e-56 191.0 6.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Antimicrobial10 PF08105.6 EEQ29685.1 - 0.55 9.8 4.6 2.2 7.9 0.1 2.9 2 0 0 2 2 2 0 Metchnikowin family Tom37_C PF11801.3 EEQ29686.1 - 2e-35 122.1 0.0 4.7e-35 120.9 0.0 1.6 2 0 0 2 2 2 1 Tom37 C-terminal domain Tom37 PF10568.4 EEQ29686.1 - 3.5e-25 88.0 0.1 1.3e-24 86.1 0.0 2.0 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein DUF2317 PF10079.4 EEQ29690.1 - 0.11 11.0 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) NAPRTase PF04095.11 EEQ29691.1 - 1.1e-51 175.5 0.1 3.5e-27 95.2 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family SNARE PF05739.14 EEQ29693.1 - 6.8e-12 44.8 3.4 6.8e-12 44.8 2.4 2.4 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EEQ29693.1 - 1.3e-08 34.8 8.5 2.9e-06 27.3 5.9 2.9 1 1 0 1 1 1 1 Syntaxin Use1 PF09753.4 EEQ29693.1 - 5.7e-06 25.9 4.7 7.9e-06 25.4 3.2 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Syntaxin_2 PF14523.1 EEQ29693.1 - 6.1e-06 26.2 0.6 6.1e-06 26.2 0.4 3.0 1 1 1 2 2 2 1 Syntaxin-like protein Spectrin PF00435.16 EEQ29693.1 - 0.0011 19.2 7.9 0.087 13.1 0.0 3.3 3 1 0 3 3 3 1 Spectrin repeat COG2 PF06148.6 EEQ29693.1 - 0.0025 17.7 4.0 0.0052 16.6 0.1 2.7 1 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Rifin_STEVOR PF02009.11 EEQ29693.1 - 0.0037 16.9 3.3 0.0058 16.3 2.2 1.4 1 1 0 1 1 1 1 Rifin/stevor family TBPIP PF07106.8 EEQ29693.1 - 0.023 14.2 7.1 0.99 8.9 0.1 2.3 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Gp-FAR-1 PF05823.7 EEQ29693.1 - 0.029 14.3 2.4 0.075 12.9 0.1 2.2 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PTA_PTB PF01515.14 EEQ29693.1 - 0.035 13.1 1.7 0.056 12.4 1.2 1.3 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase ISG65-75 PF11727.3 EEQ29693.1 - 0.057 12.4 11.6 0.055 12.5 1.2 2.5 2 1 1 3 3 3 0 Invariant surface glycoprotein MCPsignal PF00015.16 EEQ29693.1 - 0.06 12.8 11.2 0.17 11.4 4.7 2.6 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF912 PF06024.7 EEQ29693.1 - 0.072 13.1 0.4 0.072 13.1 0.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1664 PF07889.7 EEQ29693.1 - 0.082 12.7 6.9 2.1 8.1 0.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) PBP1_TM PF14812.1 EEQ29693.1 - 0.088 13.1 2.6 0.11 12.7 0.2 2.5 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3753 PF12575.3 EEQ29693.1 - 0.11 12.3 2.8 0.25 11.1 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) MT0933_antitox PF14013.1 EEQ29693.1 - 0.12 12.4 0.6 0.59 10.2 0.1 2.4 2 1 0 2 2 2 0 MT0933-like antitoxin protein NEP PF10167.4 EEQ29693.1 - 0.12 12.0 4.1 0.066 12.9 0.5 2.2 2 1 0 2 2 2 0 Uncharacterised conserved protein Baculo_PEP_C PF04513.7 EEQ29693.1 - 0.17 11.6 1.1 16 5.3 0.0 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tweety PF04906.8 EEQ29693.1 - 0.26 9.6 3.4 0.22 9.8 1.0 1.8 2 0 0 2 2 2 0 Tweety LMBR1 PF04791.11 EEQ29693.1 - 0.33 9.4 5.6 0.76 8.2 3.9 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF607 PF04678.8 EEQ29693.1 - 0.33 10.8 6.2 0.13 12.1 0.6 2.3 1 1 0 2 2 2 0 Protein of unknown function, DUF607 MitMem_reg PF13012.1 EEQ29693.1 - 0.37 10.8 4.4 2.8 8.0 2.0 2.6 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function DUF805 PF05656.9 EEQ29693.1 - 0.37 10.6 1.8 0.63 9.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF3904 PF13044.1 EEQ29693.1 - 0.43 8.9 3.6 0.29 9.5 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3904) Baculo_11_kDa PF06143.6 EEQ29693.1 - 0.48 9.8 5.4 1.8 7.9 3.7 2.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family 7tm_7 PF08395.7 EEQ29693.1 - 0.59 9.1 9.5 0.88 8.5 0.4 2.6 3 0 0 3 3 3 0 7tm Chemosensory receptor SP_C-Propep PF08999.5 EEQ29693.1 - 1.8 8.1 5.2 3.2 7.3 3.6 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Fib_alpha PF08702.5 EEQ29693.1 - 2.6 8.1 13.2 4.7 7.3 0.7 3.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 EEQ29693.1 - 4.9 7.6 11.7 1.5 9.2 0.5 3.6 1 1 3 4 4 4 0 Syntaxin 6, N-terminal SPX PF03105.14 EEQ29693.1 - 6.8 6.3 9.0 2.5 7.7 4.1 1.7 1 1 1 2 2 2 0 SPX domain HisKA_3 PF07730.8 EEQ29693.1 - 9.2 6.7 10.2 3.6 8.0 0.1 4.1 3 2 2 5 5 5 0 Histidine kinase DUF972 PF06156.8 EEQ29693.1 - 10 6.5 8.3 11 6.4 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) BolA PF01722.13 EEQ29694.1 - 1.6e-29 101.6 0.4 2e-29 101.3 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.6 EEQ29694.1 - 0.014 15.7 0.1 0.017 15.5 0.0 1.4 1 1 0 1 1 1 0 Replication protein A C terminal AMP-binding PF00501.23 EEQ29695.1 - 5.4e-64 216.1 0.0 6.7e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ29695.1 - 4.7e-11 43.4 0.0 8.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.13 EEQ29696.1 - 1.2e-57 194.0 1.8 1.5e-57 193.6 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.7 EEQ29697.1 - 8.1e-24 83.0 0.4 1.3e-23 82.3 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.15 EEQ29698.1 - 5.7e-29 99.6 3.7 2.4e-28 97.6 1.4 2.6 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EEQ29698.1 - 3e-21 74.4 0.0 5.2e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Bac_rhodopsin PF01036.13 EEQ29700.1 - 5.4e-40 137.0 20.6 6.5e-40 136.8 14.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3810 PF12725.2 EEQ29700.1 - 0.8 8.5 11.5 1.3 7.8 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) Wzy_C PF04932.10 EEQ29700.1 - 1.4 8.7 14.2 0.51 10.1 3.9 2.7 2 1 0 2 2 2 0 O-Antigen ligase NfeD PF01957.13 EEQ29700.1 - 3.9 7.6 11.4 1.2 9.3 1.2 3.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Glycos_transf_4 PF00953.16 EEQ29700.1 - 4 7.2 14.8 0.93 9.2 6.3 2.5 2 1 0 2 2 2 0 Glycosyl transferase family 4 DUF3278 PF11683.3 EEQ29700.1 - 4.8 7.1 10.7 0.58 10.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) tRNA-synt_1 PF00133.17 EEQ29701.1 - 2.1e-162 541.2 0.0 2.8e-162 540.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) UPF0183 PF03676.9 EEQ29701.1 - 3.1e-40 137.9 0.0 5e-30 104.3 0.0 3.1 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) Anticodon_1 PF08264.8 EEQ29701.1 - 1.2e-22 80.3 1.8 2.3e-22 79.3 1.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEQ29701.1 - 9.3e-21 73.9 0.0 3.7e-12 45.6 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EEQ29701.1 - 0.059 12.4 0.0 3.4 6.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EEQ29701.1 - 0.17 11.1 0.0 0.4 9.9 0.0 1.5 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 EEQ29701.1 - 0.23 11.1 7.1 0.87 9.2 4.9 2.0 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Kinesin PF00225.18 EEQ29702.1 - 5.8e-107 357.2 0.3 1.7e-106 355.7 0.2 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EEQ29702.1 - 1.1e-05 25.6 1.2 1.1e-05 25.6 0.8 5.2 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding zf-Apc11 PF12861.2 EEQ29704.1 - 6.4e-47 157.3 11.1 7.2e-47 157.1 7.7 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EEQ29704.1 - 7.8e-33 112.4 9.1 9e-33 112.2 6.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEQ29704.1 - 7.6e-09 35.2 16.5 3.6e-08 33.0 11.2 2.3 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ29704.1 - 6.1e-06 25.8 11.2 0.00027 20.5 7.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ29704.1 - 0.00014 21.8 13.6 0.0012 18.7 9.4 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ29704.1 - 0.00022 20.7 13.0 0.00088 18.8 9.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EEQ29704.1 - 0.00051 19.5 10.8 0.024 14.1 5.4 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EEQ29704.1 - 0.0011 18.6 14.5 0.011 15.4 10.2 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEQ29704.1 - 0.0027 17.5 3.5 0.0027 17.5 2.4 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EEQ29704.1 - 0.0047 16.8 16.0 0.11 12.5 11.1 3.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-DBF PF07535.7 EEQ29704.1 - 0.055 13.1 2.9 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 DBF zinc finger zf-RING_3 PF14369.1 EEQ29704.1 - 0.075 13.0 5.3 3.8 7.5 0.1 3.2 3 0 0 3 3 3 0 zinc-finger DUF2256 PF10013.4 EEQ29704.1 - 0.18 11.5 0.6 0.18 11.5 0.4 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Nse PF11789.3 EEQ29704.1 - 0.21 11.1 5.0 0.4 10.2 3.5 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 EEQ29704.1 - 0.26 11.1 10.6 3.9 7.3 0.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon Opy2 PF09463.5 EEQ29704.1 - 0.43 10.7 10.3 1.6 8.8 4.1 2.2 2 0 0 2 2 2 0 Opy2 protein PHD PF00628.24 EEQ29704.1 - 0.51 10.0 13.0 2 8.1 9.0 2.0 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EEQ29704.1 - 0.62 10.1 11.4 3 7.9 7.9 2.1 1 1 0 1 1 1 0 RING-like domain RecR PF02132.10 EEQ29704.1 - 1.5 8.3 5.0 5.5 6.5 0.1 3.0 3 0 0 3 3 3 0 RecR protein zf-RING_UBOX PF13445.1 EEQ29704.1 - 1.6 8.5 9.4 3.7 7.3 4.3 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 EEQ29704.1 - 2.2 8.4 9.6 14 5.9 6.8 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain DUF329 PF03884.9 EEQ29704.1 - 3.7 7.1 9.1 0.97 9.0 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF329) zf-HC5HC2H_2 PF13832.1 EEQ29704.1 - 3.9 7.5 8.9 1.1 9.3 3.4 2.0 1 1 1 2 2 2 0 PHD-zinc-finger like domain RINGv PF12906.2 EEQ29704.1 - 5.8 7.0 13.0 17 5.5 8.5 2.2 1 1 1 2 2 2 0 RING-variant domain zf-HIT PF04438.11 EEQ29704.1 - 6.1 6.5 10.3 2.2 8.0 3.1 2.4 2 1 0 2 2 2 0 HIT zinc finger Rhodanese PF00581.15 EEQ29705.1 - 2.2e-20 73.1 0.0 1e-09 38.7 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain PIN_4 PF13638.1 EEQ29706.1 - 0.00041 20.4 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 2 PIN domain UAE_UbL PF14732.1 EEQ29706.1 - 0.03 14.4 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DUF2007 PF09413.5 EEQ29707.1 - 0.051 13.4 0.0 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) Metallophos_2 PF12850.2 EEQ29708.1 - 4.1e-06 26.7 0.8 1.7e-05 24.7 0.5 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEQ29708.1 - 0.00029 20.2 5.2 0.001 18.4 3.6 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase RPEL PF02755.10 EEQ29709.1 - 4e-21 73.6 5.4 8.8e-07 28.0 0.2 3.4 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.1 EEQ29709.1 - 0.12 12.6 0.6 1 9.6 0.2 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Translin PF01997.11 EEQ29710.1 - 8.6e-62 208.2 0.0 1.1e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Translin family DUF3375 PF11855.3 EEQ29710.1 - 0.0062 15.3 1.1 0.035 12.8 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3375) SF-assemblin PF06705.6 EEQ29710.1 - 0.011 14.9 1.3 0.018 14.2 0.2 1.8 2 0 0 2 2 2 0 SF-assemblin/beta giardin NPV_P10 PF05531.7 EEQ29710.1 - 0.37 11.0 1.7 26 5.1 0.0 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans PF05007.8 EEQ29711.1 - 7.6e-79 264.9 12.7 1.3e-78 264.2 8.8 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EEQ29711.1 - 3.7e-13 49.1 4.2 3.7e-13 49.1 2.9 2.2 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EEQ29711.1 - 1.6e-06 27.8 5.5 1.6e-06 27.8 3.8 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) F-box-like PF12937.2 EEQ29712.1 - 0.0019 17.9 0.0 0.0064 16.1 0.0 2.0 1 1 0 1 1 1 1 F-box-like Menin PF05053.8 EEQ29713.1 - 0.66 8.0 7.2 1.1 7.3 5.0 1.3 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 EEQ29713.1 - 0.89 8.8 13.8 1.4 8.2 9.5 1.2 1 0 0 1 1 1 0 Vta1 like SQS_PSY PF00494.14 EEQ29714.1 - 4.7e-42 144.1 0.0 1.5e-41 142.4 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase Amidohydro_2 PF04909.9 EEQ29715.1 - 7.8e-12 45.3 0.3 4.5e-11 42.8 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EEQ29715.1 - 8.2e-08 32.6 0.6 1.1e-07 32.2 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EEQ29715.1 - 1.4e-07 31.5 0.2 2.3e-07 30.8 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.1 EEQ29715.1 - 0.0082 16.3 0.1 0.036 14.2 0.1 2.0 2 1 0 2 2 2 1 CoA binding domain DnaJ-X PF14308.1 EEQ29716.1 - 2.7e-74 248.8 5.1 2.7e-74 248.8 3.5 3.1 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EEQ29716.1 - 7.5e-26 89.6 0.1 2.4e-25 88.0 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain OrfB_IS605 PF01385.14 EEQ29716.1 - 0.034 13.5 2.5 0.073 12.4 1.7 1.5 1 0 0 1 1 1 0 Probable transposase IMS PF00817.15 EEQ29718.1 - 4.5e-42 143.3 0.7 1e-41 142.2 0.5 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EEQ29718.1 - 2.4e-14 53.3 0.1 5.8e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EEQ29718.1 - 6.1e-06 25.9 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Moricin PF06451.6 EEQ29718.1 - 0.00058 19.3 0.5 1.4 8.4 0.0 2.9 3 0 0 3 3 3 2 Moricin FHA PF00498.21 EEQ29719.1 - 3.8e-05 23.7 0.2 8.2e-05 22.6 0.2 1.6 1 0 0 1 1 1 1 FHA domain Ferritin_2 PF13668.1 EEQ29721.1 - 2.1e-15 56.8 0.2 3.3e-15 56.2 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.19 EEQ29722.1 - 3.3e-18 65.5 24.6 3e-11 42.5 5.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Unstab_antitox PF09720.5 EEQ29723.1 - 0.068 12.8 0.6 0.15 11.8 0.5 1.5 1 0 0 1 1 1 0 Putative addiction module component Pkinase PF00069.20 EEQ29724.1 - 2.7e-27 95.5 0.0 1.2e-26 93.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29724.1 - 7.8e-12 44.8 0.0 5.3e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase AMP-binding PF00501.23 EEQ29725.1 - 2e-75 253.7 0.0 2.4e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ29725.1 - 2e-10 41.4 0.3 4.5e-10 40.3 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EEQ29726.1 - 5.1e-27 94.5 22.1 4.5e-22 78.2 10.0 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sensor PF13796.1 EEQ29726.1 - 0.00014 21.5 3.8 0.00014 21.5 2.7 3.4 3 1 0 3 3 3 1 Putative sensor MerE PF05052.7 EEQ29726.1 - 0.15 12.0 7.6 0.031 14.2 2.3 2.1 2 0 0 2 2 2 0 MerE protein VGCC_beta4Aa_N PF12052.3 EEQ29727.1 - 0.043 13.6 0.5 0.12 12.2 0.4 1.8 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal CoA_binding_2 PF13380.1 EEQ29728.1 - 7.7e-27 93.7 0.0 9.7e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.7 EEQ29730.1 - 1.9e-23 82.7 0.0 4.5e-23 81.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ29730.1 - 3.9e-15 56.4 0.0 7.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ29730.1 - 6.4e-15 55.2 0.0 9.1e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ29730.1 - 1.3e-14 54.0 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ29730.1 - 5.3e-14 52.3 0.0 1.2e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ29730.1 - 7.7e-12 45.5 0.0 1.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ29730.1 - 2.9e-09 36.3 0.0 9e-09 34.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEQ29730.1 - 1.6e-07 31.3 0.0 4.2e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ29730.1 - 8.7e-05 21.9 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EEQ29730.1 - 0.0004 19.5 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 EEQ29730.1 - 0.00092 18.1 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase tRNA_U5-meth_tr PF05958.6 EEQ29730.1 - 0.0058 15.3 0.0 0.0089 14.7 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase CMAS PF02353.15 EEQ29730.1 - 0.0074 15.3 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EEQ29730.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_32 PF13679.1 EEQ29730.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EEQ29730.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.9 EEQ29730.1 - 0.026 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.7 EEQ29730.1 - 0.035 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NodS PF05401.6 EEQ29730.1 - 0.036 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 EEQ29730.1 - 0.037 13.0 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 EEQ29730.1 - 0.078 13.8 0.0 0.19 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HIT PF01230.18 EEQ29731.1 - 1.3e-24 86.5 0.6 4.3e-24 84.8 0.1 1.9 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EEQ29731.1 - 7.2e-09 35.8 0.1 1.4e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EEQ29731.1 - 0.0032 17.1 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.12 EEQ29731.1 - 0.029 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain dCMP_cyt_deam_1 PF00383.17 EEQ29732.1 - 3e-07 30.0 0.0 3.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Chitin_synth_1 PF01644.12 EEQ29733.1 - 3.8e-83 277.1 0.2 7.7e-83 276.1 0.0 1.6 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 EEQ29733.1 - 4.7e-34 115.9 0.1 1e-33 114.8 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEQ29733.1 - 3.3e-22 78.5 0.3 1.3e-19 69.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EEQ29733.1 - 1.1e-07 31.8 0.5 3.1e-07 30.2 0.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ29733.1 - 4.5e-05 23.3 0.0 8.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 AFG1_ATPase PF03969.11 EEQ29734.1 - 4.6e-88 295.4 0.0 2.3e-83 280.0 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EEQ29734.1 - 0.0017 18.3 0.5 0.56 10.1 0.0 3.1 2 2 0 3 3 3 2 AAA ATPase domain AAA PF00004.24 EEQ29734.1 - 0.0093 16.1 0.0 0.041 14.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ29734.1 - 0.14 12.2 0.0 0.56 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain SH3_1 PF00018.23 EEQ29735.1 - 1.3e-24 85.2 1.4 3.7e-11 42.2 0.0 3.3 3 0 0 3 3 3 2 SH3 domain PX PF00787.19 EEQ29735.1 - 3.6e-14 52.5 0.0 7.7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 EEQ29735.1 - 7e-14 51.1 2.4 5.2e-06 25.9 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 EEQ29735.1 - 7.2e-11 41.4 0.4 5.3e-06 25.8 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.19 EEQ29735.1 - 1.7e-08 33.9 0.5 3.6e-08 32.9 0.4 1.5 1 0 0 1 1 1 1 PB1 domain zf-XS PF03470.9 EEQ29735.1 - 0.23 11.5 3.0 0.62 10.1 2.1 1.8 1 0 0 1 1 1 0 XS zinc finger domain SAC3_GANP PF03399.11 EEQ29736.1 - 4e-68 229.0 0.2 8.2e-68 227.9 0.1 1.5 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEQ29736.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 ODAM PF15424.1 EEQ29736.1 - 0.044 13.2 0.2 0.074 12.5 0.1 1.3 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family EAP30 PF04157.11 EEQ29737.1 - 1.8e-46 158.0 0.0 2.3e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EEQ29737.1 - 6.9e-17 61.0 0.0 1.2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 EEQ29737.1 - 0.00018 20.9 0.2 0.00038 19.9 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zf-MIZ PF02891.15 EEQ29737.1 - 0.024 14.1 0.1 0.063 12.7 0.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RanBP PF00641.13 EEQ29737.1 - 4.7 6.4 4.9 0.47 9.5 0.3 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others F-box PF00646.28 EEQ29739.1 - 0.00012 21.6 0.8 0.00044 19.8 0.5 2.0 1 0 0 1 1 1 1 F-box domain AA_permease PF00324.16 EEQ29740.1 - 4.4e-131 437.5 46.9 4.9e-131 437.3 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ29740.1 - 3e-26 91.9 54.6 3.8e-26 91.6 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.11 EEQ29740.1 - 0.35 11.1 0.1 0.35 11.1 0.0 3.9 4 1 1 5 5 5 0 Divalent cation transporter PHP PF02811.14 EEQ29741.1 - 2.5e-07 30.6 0.0 5.2e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 PHP domain AAT PF03417.11 EEQ29743.1 - 7e-32 110.6 0.0 8.7e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EEQ29743.1 - 3.6e-06 27.2 0.0 6.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase MTP18 PF10558.4 EEQ29744.1 - 1.1e-66 223.3 0.2 1.6e-66 222.7 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2964 PF11177.3 EEQ29744.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) MFS_1 PF07690.11 EEQ29746.1 - 3.9e-37 127.7 34.8 1e-25 90.2 12.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ29746.1 - 0.042 13.6 0.1 0.042 13.6 0.1 2.5 3 0 0 3 3 3 0 MFS_1 like family Cys_Met_Meta_PP PF01053.15 EEQ29747.1 - 1.7e-139 464.4 0.0 1.9e-139 464.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEQ29747.1 - 1.6e-06 27.3 0.0 2.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EEQ29747.1 - 0.00014 21.0 0.0 0.0005 19.2 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family SelA PF03841.8 EEQ29747.1 - 0.00092 18.0 0.1 0.0021 16.8 0.0 1.5 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.16 EEQ29747.1 - 0.0014 17.8 0.0 0.0036 16.4 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase AAA PF00004.24 EEQ29748.1 - 1.8e-37 128.4 0.0 5.3e-37 126.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEQ29748.1 - 4.6e-06 26.5 0.0 1.6e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEQ29748.1 - 1.3e-05 25.9 0.2 6.5e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EEQ29748.1 - 1.9e-05 24.3 0.1 0.00021 21.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ29748.1 - 2.1e-05 24.6 0.3 0.00091 19.3 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.1 EEQ29748.1 - 2.2e-05 24.5 0.2 0.00058 19.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EEQ29748.1 - 3.6e-05 22.9 0.0 6.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EEQ29748.1 - 0.00015 21.7 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EEQ29748.1 - 0.0002 20.7 0.1 0.028 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EEQ29748.1 - 0.00022 20.6 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EEQ29748.1 - 0.00034 20.4 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EEQ29748.1 - 0.00084 19.3 0.0 0.003 17.5 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EEQ29748.1 - 0.00087 18.5 0.1 0.0018 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEQ29748.1 - 0.0013 18.9 0.0 0.0044 17.1 0.0 2.1 2 1 0 2 2 1 1 RNA helicase Parvo_NS1 PF01057.12 EEQ29748.1 - 0.0017 17.2 0.0 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 EEQ29748.1 - 0.0017 18.0 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EEQ29748.1 - 0.003 17.2 0.1 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 EEQ29748.1 - 0.0035 16.4 0.3 0.0058 15.7 0.0 1.6 2 0 0 2 2 1 1 Zeta toxin AAA_28 PF13521.1 EEQ29748.1 - 0.0036 17.2 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ29748.1 - 0.0059 16.9 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EEQ29748.1 - 0.0064 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EEQ29748.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EEQ29748.1 - 0.022 15.0 0.3 0.075 13.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 EEQ29748.1 - 0.054 12.3 0.1 0.2 10.4 0.0 1.9 3 0 0 3 3 3 0 NB-ARC domain CPT PF07931.7 EEQ29748.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.8 EEQ29748.1 - 0.061 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 EEQ29748.1 - 0.063 12.8 0.3 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EEQ29748.1 - 0.068 12.8 0.0 0.25 10.9 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 EEQ29748.1 - 0.075 11.6 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 EEQ29748.1 - 0.11 11.2 0.0 0.3 9.7 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus Viral_helicase1 PF01443.13 EEQ29748.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Csm1 PF12539.3 EEQ29749.1 - 3.4e-28 97.9 0.1 1.7e-27 95.7 0.1 2.2 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 V_ATPase_I PF01496.14 EEQ29749.1 - 0.00036 18.5 3.9 0.00052 18.0 2.7 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MscS_porin PF12795.2 EEQ29749.1 - 0.00038 19.8 13.2 0.00076 18.8 9.2 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain IFT57 PF10498.4 EEQ29749.1 - 0.0035 16.1 13.4 0.0035 16.1 9.3 2.6 2 1 1 3 3 3 1 Intra-flagellar transport protein 57 Spc42p PF11544.3 EEQ29749.1 - 0.004 17.0 6.8 0.004 17.0 4.7 3.0 2 1 1 3 3 2 1 Spindle pole body component Spc42p Filament PF00038.16 EEQ29749.1 - 0.0046 16.4 12.3 0.0093 15.4 8.5 1.5 1 0 0 1 1 1 1 Intermediate filament protein DUF2968 PF11180.3 EEQ29749.1 - 0.0053 16.1 11.8 0.011 15.0 8.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) TPR_MLP1_2 PF07926.7 EEQ29749.1 - 0.0057 16.3 18.0 0.017 14.8 12.5 1.9 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein OmpH PF03938.9 EEQ29749.1 - 0.0073 16.2 9.6 0.017 15.0 6.7 1.6 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Spc7 PF08317.6 EEQ29749.1 - 0.01 14.5 13.7 0.017 13.8 9.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EEQ29749.1 - 0.011 14.9 2.5 0.02 14.0 1.7 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 EEQ29749.1 - 0.028 13.9 11.3 0.061 12.8 7.9 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 EEQ29749.1 - 0.032 13.1 12.4 0.077 11.9 8.6 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 COG6 PF06419.6 EEQ29749.1 - 0.037 12.1 13.6 0.051 11.7 9.4 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 COG5 PF10392.4 EEQ29749.1 - 0.068 13.1 7.7 0.13 12.1 5.3 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 IncA PF04156.9 EEQ29749.1 - 0.077 12.5 17.7 0.016 14.7 9.8 1.7 2 0 0 2 2 1 0 IncA protein DUF3450 PF11932.3 EEQ29749.1 - 0.086 12.0 11.8 0.17 11.1 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Allexi_40kDa PF05549.6 EEQ29749.1 - 0.11 11.7 7.9 0.042 13.1 3.6 1.6 2 0 0 2 2 1 0 Allexivirus 40kDa protein DUF4618 PF15397.1 EEQ29749.1 - 0.2 10.9 12.3 0.37 10.0 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Pox_A_type_inc PF04508.7 EEQ29749.1 - 0.22 11.3 3.0 1.7 8.6 0.1 3.4 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Lge1 PF11488.3 EEQ29749.1 - 0.55 10.4 9.5 1.7 8.8 6.2 2.2 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Med9 PF07544.8 EEQ29749.1 - 0.57 9.9 15.0 2.4 7.9 8.3 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.7 EEQ29749.1 - 0.66 9.7 9.7 0.44 10.3 5.2 1.7 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EEQ29749.1 - 0.71 9.6 5.4 1.6 8.5 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tweety PF04906.8 EEQ29749.1 - 0.99 7.7 4.3 1.5 7.1 3.0 1.1 1 0 0 1 1 1 0 Tweety GLE1 PF07817.8 EEQ29749.1 - 1.2 8.0 8.1 2 7.2 5.6 1.3 1 0 0 1 1 1 0 GLE1-like protein GAS PF13851.1 EEQ29749.1 - 1.5 8.0 17.9 2.1 7.4 11.7 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prominin PF05478.6 EEQ29749.1 - 1.9 5.8 7.1 2.8 5.3 4.9 1.2 1 0 0 1 1 1 0 Prominin Macoilin PF09726.4 EEQ29749.1 - 3 6.0 27.8 4.3 5.5 19.2 1.1 1 0 0 1 1 1 0 Transmembrane protein CorA PF01544.13 EEQ29749.1 - 3.4 6.6 4.9 6.2 5.7 3.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.5 EEQ29749.1 - 3.8 7.6 14.1 9.9 6.2 9.3 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.8 EEQ29749.1 - 4.4 6.2 10.9 6.6 5.7 7.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein TEX13 PF15186.1 EEQ29749.1 - 5.9 6.4 11.5 30 4.1 7.2 2.2 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family THOC7 PF05615.8 EEQ29749.1 - 6.2 7.0 19.3 35 4.6 12.1 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 DUF3340 PF11818.3 EEQ29749.1 - 7.3 6.5 17.7 0.14 12.0 5.6 2.3 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF4446 PF14584.1 EEQ29749.1 - 7.4 6.3 12.8 3.9 7.2 1.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Mnd1 PF03962.10 EEQ29749.1 - 8.8 5.9 18.3 0.32 10.6 7.1 2.4 2 0 0 2 2 2 0 Mnd1 family AAA_13 PF13166.1 EEQ29749.1 - 10 4.4 20.5 0.061 11.7 8.1 1.6 2 0 0 2 2 2 0 AAA domain PigN PF04987.9 EEQ29750.1 - 2e-161 537.5 31.5 2.7e-161 537.1 21.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EEQ29750.1 - 2.5e-12 46.8 0.7 1.4e-10 41.0 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEQ29750.1 - 1.9e-09 37.1 0.1 3.3e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EEQ29750.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily APH PF01636.18 EEQ29751.1 - 1.2e-11 44.8 0.1 6.8e-08 32.5 0.0 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ29751.1 - 1.2e-07 31.5 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ29751.1 - 0.085 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fungal_trans PF04082.13 EEQ29752.1 - 8.6e-18 64.1 0.1 3.9e-11 42.3 0.0 3.5 2 1 1 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ29752.1 - 0.0031 17.3 1.2 0.006 16.4 0.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.15 EEQ29753.1 - 0.0043 16.9 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 LysM domain UPF0079 PF02367.12 EEQ29754.1 - 0.035 13.7 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 GSCFA PF08885.6 EEQ29754.1 - 0.11 12.0 0.1 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 GSCFA family KAP_NTPase PF07693.9 EEQ29754.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain adh_short PF00106.20 EEQ29756.1 - 5.3e-58 195.6 4.6 3.6e-29 101.8 0.7 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EEQ29756.1 - 2.9e-31 107.4 0.0 5.1e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EEQ29756.1 - 2.2e-26 92.6 1.1 1.9e-12 47.2 0.2 2.4 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EEQ29756.1 - 1.6e-15 57.5 0.5 3.4e-08 33.5 0.0 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EEQ29756.1 - 7.6e-05 21.8 0.5 0.0095 15.0 0.4 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EEQ29756.1 - 0.56 9.8 4.7 12 5.5 0.8 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HTH_Tnp_Tc3_2 PF01498.13 EEQ29757.1 - 0.085 12.9 0.2 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Transposase Yip1 PF04893.12 EEQ29758.1 - 3.4e-09 36.4 8.4 6.8e-09 35.4 5.5 1.7 2 0 0 2 2 2 1 Yip1 domain DUF1282 PF06930.7 EEQ29758.1 - 0.02 14.5 3.4 0.035 13.7 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Cu-oxidase_3 PF07732.10 EEQ29759.1 - 5.3e-44 148.7 0.2 4.4e-42 142.5 0.4 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEQ29759.1 - 9.2e-41 138.5 6.9 1.5e-36 124.9 0.1 4.2 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.17 EEQ29759.1 - 6.4e-25 87.9 0.0 6.5e-24 84.6 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase MMR_HSR1 PF01926.18 EEQ29760.1 - 2.5e-08 33.8 0.2 3.2e-07 30.3 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EEQ29760.1 - 1.2e-07 31.0 0.0 3.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EEQ29760.1 - 0.00012 21.3 0.0 0.0003 20.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EEQ29760.1 - 0.0013 19.2 0.4 0.0051 17.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EEQ29760.1 - 0.0031 16.7 0.3 0.0082 15.4 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.13 EEQ29760.1 - 0.0038 16.2 0.0 0.0038 16.2 0.0 2.3 2 1 0 2 2 2 1 Septin IIGP PF05049.8 EEQ29760.1 - 0.0053 15.6 0.1 0.016 14.0 0.0 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) SRPRB PF09439.5 EEQ29760.1 - 0.0087 15.2 0.0 0.0087 15.2 0.0 2.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EEQ29760.1 - 0.015 15.4 1.7 0.025 14.7 0.0 2.3 2 2 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EEQ29760.1 - 0.022 14.5 14.4 0.036 13.8 0.0 3.8 2 2 1 3 3 3 0 Dynamin family NB-ARC PF00931.17 EEQ29760.1 - 0.027 13.3 1.9 0.035 12.9 0.1 2.1 3 1 0 3 3 3 0 NB-ARC domain Viral_helicase1 PF01443.13 EEQ29760.1 - 0.033 13.6 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 EEQ29760.1 - 0.066 12.7 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4407 PF14362.1 EEQ29760.1 - 0.075 11.9 15.8 0.048 12.6 9.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATP_bind_1 PF03029.12 EEQ29760.1 - 0.079 12.4 3.1 0.52 9.8 0.2 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EEQ29760.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.6 2 1 0 2 2 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 EEQ29760.1 - 0.26 10.7 0.1 0.26 10.7 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EEQ29760.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain FUSC PF04632.7 EEQ29760.1 - 0.34 9.2 2.7 0.46 8.8 1.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Gp58 PF07902.6 EEQ29760.1 - 0.43 8.7 6.6 0.6 8.2 4.6 1.1 1 0 0 1 1 1 0 gp58-like protein AAA_16 PF13191.1 EEQ29760.1 - 0.62 10.0 3.0 4.8 7.1 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain SRP54 PF00448.17 EEQ29760.1 - 0.78 9.1 5.1 7.1 6.0 0.0 3.2 2 2 2 4 4 4 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 EEQ29760.1 - 1 8.7 7.5 0.26 10.7 1.3 2.6 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EEQ29760.1 - 1.2 9.9 0.0 1.2 9.9 0.0 2.7 2 1 0 2 2 1 0 AAA domain ADIP PF11559.3 EEQ29761.1 - 0.0021 17.9 2.8 0.004 17.0 1.9 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EEQ29761.1 - 0.01 16.2 0.3 0.032 14.5 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EEQ29761.1 - 0.19 11.5 6.8 2 8.2 0.1 2.5 1 1 1 2 2 2 0 Basic region leucine zipper HSP70 PF00012.15 EEQ29762.1 - 4.6e-11 41.3 0.0 5.9e-10 37.6 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EEQ29762.1 - 0.032 12.8 0.0 0.052 12.1 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein Ran_BP1 PF00638.13 EEQ29763.1 - 7.5e-08 32.4 0.3 1.7e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 RanBP1 domain DUF572 PF04502.8 EEQ29763.1 - 1.4 8.0 29.9 0.12 11.6 13.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DEAD PF00270.24 EEQ29764.1 - 1.2e-22 80.2 0.0 2.1e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ29764.1 - 5.9e-11 42.0 0.1 2.4e-10 40.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EEQ29764.1 - 4.5e-10 39.9 0.2 3.2e-07 30.8 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1998) ResIII PF04851.10 EEQ29764.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CDT1 PF08839.6 EEQ29764.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor CDT1 like Fungal_trans_2 PF11951.3 EEQ29765.1 - 7.6e-15 54.3 6.3 4.5e-14 51.8 4.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ29765.1 - 2.7e-05 23.9 11.5 5.8e-05 22.9 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 EEQ29767.1 - 1.9e-65 220.8 0.0 2.9e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 EEQ29767.1 - 1e-13 50.0 2.1 1.2e-06 27.7 0.1 6.6 7 0 0 7 7 7 3 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 EEQ29767.1 - 2.8e-12 46.6 0.1 8.5e-12 45.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.1 EEQ29767.1 - 6.4e-06 25.6 18.3 0.029 13.9 0.3 5.7 5 1 1 6 6 6 4 Hexapeptide repeat of succinyl-transferase AMP-binding_C PF13193.1 EEQ29767.1 - 0.0034 18.2 0.0 0.01 16.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EEQ29767.1 - 0.4 9.1 0.6 15 3.9 0.1 2.4 3 0 0 3 3 3 0 GH3 auxin-responsive promoter zf-RING_2 PF13639.1 EEQ29768.1 - 9.2e-15 54.2 8.0 1.5e-14 53.5 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEQ29768.1 - 1.2e-08 34.9 4.9 2.2e-08 34.0 3.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EEQ29768.1 - 2.8e-06 27.2 7.9 4.6e-06 26.5 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ29768.1 - 5.6e-06 25.9 7.6 8.9e-06 25.2 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ29768.1 - 3.8e-05 23.4 1.8 8.2e-05 22.3 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EEQ29768.1 - 7.7e-05 22.3 5.9 0.00012 21.7 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ29768.1 - 0.00047 19.7 5.5 0.00074 19.1 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EEQ29768.1 - 0.011 15.7 8.9 0.018 15.0 6.1 1.3 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EEQ29768.1 - 0.044 13.4 2.2 0.095 12.4 1.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EEQ29768.1 - 0.099 12.6 6.1 0.18 11.7 4.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 EEQ29768.1 - 0.1 12.0 3.7 0.19 11.2 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 EEQ29768.1 - 0.45 10.5 3.5 0.88 9.6 2.4 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 EEQ29768.1 - 2.4 7.9 9.4 1.6 8.5 5.3 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EEQ29768.1 - 8.4 6.0 7.0 16 5.1 4.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ECM11 PF15463.1 EEQ29769.1 - 3.5e-35 121.2 0.1 1.3e-34 119.4 0.0 2.1 2 0 0 2 2 2 1 Extracellular mutant protein 11 RNA_pol_I_TF PF04090.7 EEQ29770.1 - 2.4e-05 23.7 0.0 0.014 14.6 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor Tom37_C PF11801.3 EEQ29770.1 - 0.9 9.3 3.6 0.91 9.3 0.6 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain bZIP_Maf PF03131.12 EEQ29771.1 - 9.3e-06 25.8 14.6 9.3e-06 25.8 10.1 3.7 3 1 1 4 4 4 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EEQ29771.1 - 0.00013 21.6 12.3 0.00013 21.6 8.6 3.5 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EEQ29771.1 - 0.0019 18.0 14.7 0.0019 18.0 10.2 3.4 1 1 3 4 4 4 1 bZIP transcription factor DUF2205 PF10224.4 EEQ29771.1 - 0.14 11.7 13.0 0.2 11.2 7.9 2.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) AAA_23 PF13476.1 EEQ29771.1 - 1.6 9.0 10.3 3.5 7.9 7.2 1.6 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EEQ29771.1 - 8.8 5.2 20.0 21 4.0 13.8 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-CCCH PF00642.19 EEQ29773.1 - 5.6e-12 45.0 27.1 0.00089 18.8 1.3 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIF_beta PF02270.10 EEQ29774.1 - 7.2e-88 294.9 8.1 8.5e-88 294.7 5.6 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit PCI PF01399.22 EEQ29775.1 - 5.9e-10 39.4 0.0 1.7e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EEQ29775.1 - 6.7e-08 32.1 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 NAD_binding_4 PF07993.7 EEQ29776.1 - 7.3e-32 110.2 0.0 1.5e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EEQ29776.1 - 1.6e-30 105.8 0.0 7.8e-29 100.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 EEQ29776.1 - 4.9e-12 45.7 0.0 8.6e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EEQ29776.1 - 1.4e-08 34.8 0.1 1.3e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EEQ29776.1 - 0.0016 17.4 0.0 0.032 13.1 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.8 EEQ29776.1 - 0.027 13.7 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.17 EEQ29777.1 - 9.1e-79 265.1 0.0 1.1e-78 264.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Octopine_DH PF02317.12 EEQ29777.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain adh_short PF00106.20 EEQ29778.1 - 3e-14 53.2 0.2 5.6e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ29778.1 - 3.4e-08 33.3 0.1 5.3e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF2322 PF10084.4 EEQ29778.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) adh_short_C2 PF13561.1 EEQ29779.1 - 1.9e-29 103.1 0.1 2.3e-29 102.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ29779.1 - 2.9e-25 89.1 2.2 1e-24 87.3 1.5 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ29779.1 - 1.2e-10 41.2 0.6 3e-10 40.0 0.4 1.7 1 1 0 1 1 1 1 KR domain PD-C2-AF1 PF09310.5 EEQ29779.1 - 0.0065 15.6 0.3 1.4 8.0 0.0 2.2 2 0 0 2 2 2 2 POU domain, class 2, associating factor 1 Zn_clus PF00172.13 EEQ29780.1 - 1.7e-06 27.8 7.0 1.7e-06 27.8 4.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ29780.1 - 1.9e-05 23.6 0.3 8.7e-05 21.5 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acyl_transf_1 PF00698.16 EEQ29781.1 - 9e-91 304.5 0.0 1.5e-90 303.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EEQ29781.1 - 1.2e-77 260.8 1.1 3e-77 259.5 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEQ29781.1 - 1e-60 204.5 0.5 3.6e-60 202.7 0.0 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EEQ29781.1 - 4.9e-50 169.7 0.1 1.7e-49 167.9 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEQ29781.1 - 4.9e-42 142.5 0.5 1.5e-41 140.9 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EEQ29781.1 - 3.2e-15 56.0 0.3 6.8e-15 54.9 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EEQ29781.1 - 2.6e-11 43.6 0.0 6.1e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EEQ29781.1 - 0.00011 21.2 0.7 0.00011 21.2 0.5 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain FbpA PF05833.6 EEQ29781.1 - 0.059 11.9 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Epimerase PF01370.16 EEQ29781.1 - 0.099 12.0 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 EEQ29782.1 - 3.6e-23 81.8 45.6 3.6e-23 81.8 31.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 EEQ29783.1 - 2e-14 52.7 1.0 0.029 14.2 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat FAD_binding_2 PF00890.19 EEQ29785.1 - 5.8e-82 275.7 0.5 7.5e-82 275.3 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EEQ29785.1 - 4.2e-18 64.9 0.7 1.4e-16 59.9 0.1 3.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EEQ29785.1 - 2e-11 43.4 2.1 4.9e-10 38.8 1.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EEQ29785.1 - 1.6e-10 40.7 0.3 3.9e-10 39.3 0.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ29785.1 - 2.5e-09 37.0 0.3 2.2e-08 34.0 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ29785.1 - 1.1e-07 31.9 0.0 4.5e-05 23.4 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ29785.1 - 3.8e-06 25.6 3.8 0.00011 20.7 0.7 3.1 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EEQ29785.1 - 7.6e-05 21.7 1.4 0.022 13.6 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EEQ29785.1 - 0.0001 21.5 0.3 0.02 13.9 0.1 2.5 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 EEQ29785.1 - 0.0026 16.9 0.3 1.1 8.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EEQ29785.1 - 0.0046 16.0 0.9 0.0093 15.0 0.6 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EEQ29785.1 - 0.0074 16.3 1.3 0.025 14.6 0.5 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase P_proprotein PF01483.15 EEQ29785.1 - 0.078 12.7 0.3 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Proprotein convertase P-domain Pyr_redox PF00070.22 EEQ29785.1 - 0.12 12.7 0.8 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAH PF02671.16 EEQ29786.1 - 3.6e-46 154.5 0.5 1e-17 63.4 0.2 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EEQ29786.1 - 4.4e-41 138.7 0.1 4.4e-41 138.7 0.1 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor PRCC PF10253.4 EEQ29786.1 - 0.0035 18.0 11.5 0.0035 18.0 7.9 5.1 4 1 0 4 4 4 2 Mitotic checkpoint regulator, MAD2B-interacting Glyco_hydro_17 PF00332.13 EEQ29788.1 - 0.0099 14.9 0.1 0.66 8.9 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 MFS_1 PF07690.11 EEQ29789.1 - 1.8e-42 145.3 68.7 1e-40 139.5 47.5 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ29789.1 - 1.5e-15 56.7 12.6 1.5e-15 56.7 8.7 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EEQ29789.1 - 1e-14 53.7 29.5 2.2e-14 52.6 20.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3357 PF11837.3 EEQ29789.1 - 0.19 11.6 0.7 6.5 6.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Sel1 PF08238.7 EEQ29790.1 - 5.4e-31 106.3 40.0 6.4e-05 23.4 0.1 7.9 8 0 0 8 8 8 7 Sel1 repeat TPR_11 PF13414.1 EEQ29790.1 - 0.18 11.4 5.5 0.69 9.5 0.1 3.5 2 1 1 3 3 3 0 TPR repeat Chitin_synth_2 PF03142.10 EEQ29791.1 - 9.4e-296 981.2 0.1 9.4e-296 981.2 0.1 1.3 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EEQ29791.1 - 7.3e-18 64.9 1.9 2.9e-17 63.0 1.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ29791.1 - 1.8e-14 54.1 0.0 2.9e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEQ29791.1 - 1.7e-05 24.2 0.1 0.00019 20.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.23 EEQ29791.1 - 3e-05 23.7 0.0 8.7e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EEQ29791.1 - 0.0089 15.7 0.0 0.089 12.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 OrfB_IS605 PF01385.14 EEQ29791.1 - 6.9 5.9 7.8 4.2 6.6 3.6 1.8 2 0 0 2 2 2 0 Probable transposase WD40 PF00400.27 EEQ29792.1 - 1.6e-08 34.0 0.6 1.8e-07 30.7 0.1 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF123 PF01986.11 EEQ29792.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF123 UPF0146 PF03686.8 EEQ29792.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) ATG22 PF11700.3 EEQ29794.1 - 3.4e-116 388.5 23.1 5.4e-116 387.9 16.0 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Ras PF00071.17 EEQ29795.1 - 6e-51 172.0 0.5 7.3e-51 171.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ29795.1 - 3.2e-13 50.2 0.1 5.9e-13 49.3 0.1 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEQ29795.1 - 1.2e-10 40.8 0.1 1.4e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ29795.1 - 3.1e-08 33.2 0.0 3.7e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEQ29795.1 - 0.00019 20.6 0.0 0.00023 20.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region CTP_transf_3 PF02348.14 EEQ29795.1 - 0.027 14.1 0.2 0.1 12.2 0.1 1.7 1 1 1 2 2 2 0 Cytidylyltransferase Mitofilin PF09731.4 EEQ29796.1 - 1.2e-140 469.9 14.0 2e-140 469.2 9.7 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4363 PF14276.1 EEQ29796.1 - 0.49 10.1 4.8 0.76 9.4 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) Exonuc_VII_L PF02601.10 EEQ29796.1 - 0.6 9.2 9.3 0.93 8.6 6.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 EEQ29796.1 - 2.5 8.0 11.1 5.9 6.8 7.7 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DSBA PF01323.15 EEQ29801.1 - 9.9e-18 64.3 0.0 1.2e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Methyltransf_16 PF10294.4 EEQ29803.1 - 8.5e-42 142.5 0.0 3.4e-41 140.5 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EEQ29803.1 - 0.0014 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ29803.1 - 0.0032 17.4 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ29803.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEQ29803.1 - 0.007 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ29803.1 - 0.011 16.2 0.0 0.03 14.7 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ29803.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ29803.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Orn_Arg_deC_N PF02784.11 EEQ29804.1 - 1.7e-76 256.7 0.0 2.7e-76 256.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EEQ29804.1 - 3.3e-29 100.9 0.1 5.4e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EEQ29804.1 - 0.0027 17.0 0.0 0.0057 15.9 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Phage_fiber_2 PF03406.8 EEQ29804.1 - 0.55 9.9 3.1 1.3 8.6 2.1 1.7 1 0 0 1 1 1 0 Phage tail fibre repeat cobW PF02492.14 EEQ29805.1 - 1.1e-37 129.1 0.0 2.7e-37 127.9 0.0 1.6 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EEQ29805.1 - 0.0018 17.9 0.0 0.0041 16.7 0.0 1.8 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_19 PF13245.1 EEQ29805.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EEQ29805.1 - 0.016 14.7 0.2 0.47 10.0 0.0 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain MobB PF03205.9 EEQ29805.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EEQ29805.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ29805.1 - 0.077 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain SET PF00856.23 EEQ29806.1 - 0.0091 16.3 0.1 0.13 12.5 0.1 2.4 3 0 0 3 3 3 1 SET domain MFS_1 PF07690.11 EEQ29807.1 - 5e-33 114.2 27.9 5e-33 114.2 19.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_U4 PF03419.8 EEQ29807.1 - 3 6.8 7.4 0.19 10.7 0.9 2.0 2 1 0 2 2 2 0 Sporulation factor SpoIIGA zf-DHHC PF01529.15 EEQ29808.1 - 1.4e-36 125.5 0.0 2.2e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 EEQ29808.1 - 0.11 12.2 1.6 0.25 11.1 1.1 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF2254 PF10011.4 EEQ29808.1 - 0.12 10.7 0.1 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Acetyltransf_3 PF13302.1 EEQ29809.1 - 1e-31 110.0 0.0 1.7e-31 109.2 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ29809.1 - 2.9e-05 24.0 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EEQ29809.1 - 0.00061 19.7 0.0 0.0014 18.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EEQ29810.1 - 2.1e-71 240.1 0.0 4.5e-71 239.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29810.1 - 3.2e-44 150.9 0.0 5.4e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ29810.1 - 5.6e-06 25.5 0.0 1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 EEQ29810.1 - 3.1e-05 23.8 0.0 0.066 13.1 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region CAF1A PF12253.3 EEQ29810.1 - 0.019 15.0 0.6 0.059 13.4 0.5 1.8 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Kdo PF06293.9 EEQ29810.1 - 0.073 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 EEQ29811.1 - 3.5e-33 114.2 0.8 6.7e-33 113.3 0.5 1.5 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.4 EEQ29811.1 - 0.59 10.1 6.2 0.12 12.4 1.8 1.6 2 0 0 2 2 2 0 Mediator complex protein Macoilin PF09726.4 EEQ29811.1 - 6.4 4.9 7.5 0.22 9.7 0.5 1.7 2 0 0 2 2 2 0 Transmembrane protein Myosin_head PF00063.16 EEQ29812.1 - 1.9e-233 776.4 4.1 2.8e-233 775.9 2.8 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EEQ29812.1 - 2.9e-44 150.7 0.0 5.7e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EEQ29812.1 - 1.2e-11 43.7 0.0 2.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ29812.1 - 1.7e-08 33.8 0.0 8.3e-08 31.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EEQ29812.1 - 5.3e-08 32.2 0.0 1.4e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EEQ29812.1 - 0.0017 18.4 0.0 0.0077 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Hpr_kinase_C PF07475.7 EEQ29812.1 - 0.01 15.1 0.5 1.7 7.9 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain IQ PF00612.22 EEQ29812.1 - 0.013 15.0 8.4 0.48 10.2 0.7 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Zeta_toxin PF06414.7 EEQ29812.1 - 0.023 13.8 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EEQ29812.1 - 0.031 15.1 0.0 0.097 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 EEQ29812.1 - 0.039 12.5 0.1 0.097 11.2 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EEQ29812.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEQ29812.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain HycI PF01750.13 EEQ29812.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase maturation protease NACHT PF05729.7 EEQ29812.1 - 0.13 11.8 0.0 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain YebO PF13974.1 EEQ29813.1 - 1 9.1 3.0 2.8 7.8 2.1 1.7 1 0 0 1 1 1 0 YebO-like protein RSN1_TM PF13967.1 EEQ29813.1 - 2.6 7.5 4.8 0.31 10.5 0.4 1.5 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport p450 PF00067.17 EEQ29815.1 - 9.3e-56 189.2 0.0 2.9e-46 157.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 ABC_membrane PF00664.18 EEQ29817.1 - 1.7e-80 270.3 30.0 1.3e-40 139.5 8.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ29817.1 - 5.9e-60 201.5 0.0 1.7e-28 99.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ29817.1 - 3.9e-15 55.6 6.1 1.5e-05 24.3 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ29817.1 - 1.3e-09 38.4 2.4 0.011 15.6 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ29817.1 - 1.7e-09 37.0 0.8 0.0013 18.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ29817.1 - 6.4e-09 36.6 0.0 0.004 17.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ29817.1 - 1.3e-07 31.2 0.1 0.031 13.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EEQ29817.1 - 1.9e-07 31.3 0.8 0.0033 17.5 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ29817.1 - 6.4e-07 29.5 0.1 0.0035 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 EEQ29817.1 - 8.8e-07 29.2 0.0 0.05 13.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EEQ29817.1 - 9.6e-07 28.1 0.0 0.063 12.4 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEQ29817.1 - 6.2e-06 26.6 0.1 0.0028 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEQ29817.1 - 9.3e-05 21.9 4.0 0.19 11.1 0.1 3.7 4 0 0 4 4 4 2 AAA-like domain ABC_ATPase PF09818.4 EEQ29817.1 - 0.00026 19.7 1.2 0.066 11.7 0.3 3.3 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.1 EEQ29817.1 - 0.00037 20.3 0.0 0.64 9.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EEQ29817.1 - 0.0014 18.0 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF3987 PF13148.1 EEQ29817.1 - 0.0021 16.6 0.1 1.4 7.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA PF00004.24 EEQ29817.1 - 0.0036 17.5 0.0 0.16 12.1 0.0 3.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ29817.1 - 0.0054 16.4 0.0 0.88 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EEQ29817.1 - 0.0055 16.1 1.2 0.5 9.7 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein MobB PF03205.9 EEQ29817.1 - 0.0076 15.9 1.0 2.5 7.8 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EEQ29817.1 - 0.013 15.3 1.9 0.54 10.0 0.1 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 EEQ29817.1 - 0.016 15.1 0.1 7.3 6.5 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EEQ29817.1 - 0.017 15.2 0.2 11 6.2 0.0 2.8 3 0 0 3 3 2 0 RNA helicase MMR_HSR1 PF01926.18 EEQ29817.1 - 0.025 14.5 1.3 5 7.1 0.2 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.15 EEQ29817.1 - 0.026 14.1 0.1 8.6 5.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_13 PF13166.1 EEQ29817.1 - 0.078 11.4 1.1 18 3.6 0.1 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EEQ29817.1 - 0.091 12.4 0.1 23 4.6 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Adhesin_P1 PF03257.8 EEQ29817.1 - 0.092 13.0 0.1 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Mycoplasma adhesin P1 Guanylate_kin PF00625.16 EEQ29817.1 - 0.12 11.7 0.0 5.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase KaiC PF06745.8 EEQ29817.1 - 0.13 11.3 5.0 6.3 5.8 0.0 3.5 3 0 0 3 3 3 0 KaiC Mg_chelatase PF01078.16 EEQ29817.1 - 0.15 11.1 0.1 2.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.15 EEQ29817.1 - 0.22 10.1 0.0 1.6 7.3 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.20 EEQ29817.1 - 0.23 10.9 3.2 18 4.7 0.0 3.3 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EEQ29817.1 - 0.29 10.6 2.9 28 4.1 1.0 3.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEQ29817.1 - 1.2 8.7 2.8 9.6 5.7 0.1 2.9 3 1 0 3 3 3 0 AAA domain MFS_1 PF07690.11 EEQ29818.1 - 1.5e-28 99.5 43.0 1.5e-28 99.5 29.8 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EEQ29819.1 - 5.1e-46 157.1 0.0 6.1e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Bacteroid_pep PF14406.1 EEQ29819.1 - 0.097 12.8 0.2 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes Ric8 PF10165.4 EEQ29821.1 - 2.1e-125 419.0 0.0 3.4e-125 418.3 0.0 1.3 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Polysacc_synt_4 PF04669.8 EEQ29822.1 - 5.1e-20 71.6 0.7 2.8e-19 69.2 0.5 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis Sugar_tr PF00083.19 EEQ29823.1 - 3.2e-138 461.1 21.0 3.6e-138 460.9 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ29823.1 - 3.9e-25 88.3 34.9 7.9e-23 80.7 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EEQ29823.1 - 0.0046 15.7 1.7 0.28 9.8 1.2 2.2 1 1 0 1 1 1 1 BT1 family Pox_A14 PF05767.7 EEQ29823.1 - 0.075 12.9 0.0 0.075 12.9 0.0 3.0 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Pkinase PF00069.20 EEQ29824.1 - 9.8e-11 41.2 0.0 1.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ29824.1 - 8.8e-06 25.6 1.1 0.00015 21.6 0.5 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEQ29824.1 - 2.3e-05 23.5 0.0 3.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EEQ29824.1 - 0.0008 18.5 0.0 0.0011 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EEQ29824.1 - 0.0032 16.8 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 EEQ29824.1 - 0.047 13.0 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 EEQ29824.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Glyco_hydro_25 PF01183.15 EEQ29826.1 - 1.9e-40 138.6 0.7 2.2e-40 138.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 PsbR PF04725.7 EEQ29826.1 - 0.05 13.6 0.6 0.12 12.3 0.2 1.9 2 1 0 2 2 2 0 Photosystem II 10 kDa polypeptide PsbR Rif1_N PF12231.3 EEQ29827.1 - 4.5e-129 430.6 0.2 8.4e-129 429.7 0.1 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Aldose_epim PF01263.15 EEQ29828.1 - 2.3e-42 145.1 0.0 2.7e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase MFS_1 PF07690.11 EEQ29829.1 - 1e-25 90.1 24.7 1e-25 90.1 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sigma70_ner PF04546.8 EEQ29830.1 - 0.54 9.8 2.9 0.7 9.4 2.0 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region DAHP_synth_2 PF01474.11 EEQ29831.1 - 6.8e-197 654.1 0.0 7.7e-197 653.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family PLA2_B PF01735.13 EEQ29833.1 - 3.8e-193 642.1 1.1 4.4e-193 641.9 0.7 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Choline_transpo PF04515.7 EEQ29834.1 - 9.6e-104 346.7 16.2 9.6e-104 346.7 11.3 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter NAD_binding_1 PF00175.16 EEQ29836.1 - 6.5e-10 39.5 0.0 1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEQ29836.1 - 4.8e-09 36.2 0.0 7.9e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEQ29836.1 - 0.0044 16.9 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain p450 PF00067.17 EEQ29837.1 - 0.0092 14.5 0.1 0.035 12.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 adh_short PF00106.20 EEQ29839.1 - 2.9e-25 89.1 3.6 4.3e-23 82.0 1.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ29839.1 - 7.5e-25 88.0 0.0 1.9e-13 50.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ29839.1 - 1.6e-15 57.2 0.8 2.6e-15 56.5 0.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EEQ29839.1 - 0.00067 19.3 0.0 0.0072 15.9 0.0 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AIG2 PF06094.7 EEQ29840.1 - 2.6e-10 40.7 0.2 3.8e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 AIG2-like family CactinC_cactus PF09732.4 EEQ29840.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Piwi PF02171.12 EEQ29841.1 - 3.5e-74 249.5 0.0 5.1e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EEQ29841.1 - 8.5e-13 47.4 0.1 2.1e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EEQ29841.1 - 2.8e-12 46.0 0.0 8.6e-12 44.5 0.0 1.7 2 0 0 2 2 2 1 PAZ domain DUF663 PF04950.7 EEQ29841.1 - 0.025 13.5 0.2 0.04 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF663) Ribophorin_II PF05817.9 EEQ29843.1 - 2.4e-20 72.3 0.1 2.8e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Neisseria_TspB PF05616.8 EEQ29844.1 - 8.7 4.5 8.5 13 4.0 5.9 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein EVE PF01878.13 EEQ29846.1 - 2.5e-52 176.6 0.1 5.3e-52 175.6 0.1 1.5 1 0 0 1 1 1 1 EVE domain DUF2020 PF09449.5 EEQ29846.1 - 0.019 14.6 0.3 0.14 11.8 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2020) Methyltransf_PK PF05891.7 EEQ29847.1 - 2.3e-52 177.4 0.0 4.7e-52 176.4 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 EEQ29847.1 - 1.1e-05 24.7 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEQ29847.1 - 0.0062 17.1 0.0 0.025 15.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Aldedh PF00171.17 EEQ29848.1 - 1.1e-164 548.2 6.3 1.4e-107 359.8 0.3 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF4627 PF15425.1 EEQ29848.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4627) bZIP_2 PF07716.10 EEQ29850.1 - 6.9e-05 22.5 7.4 0.00012 21.8 5.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EEQ29850.1 - 0.0075 16.2 7.3 0.019 14.9 5.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2188 PF09954.4 EEQ29850.1 - 0.18 11.7 1.2 0.4 10.6 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) His_Phos_2 PF00328.17 EEQ29851.1 - 3.5e-51 174.5 0.0 4e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AhpC-TSA PF00578.16 EEQ29852.1 - 2.6e-32 111.1 0.0 3.7e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEQ29852.1 - 2.8e-15 56.1 0.0 4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EEQ29852.1 - 5.8e-08 32.2 0.1 1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_3 PF13415.1 EEQ29853.1 - 1.1e-18 66.8 13.0 1.4e-10 41.0 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EEQ29853.1 - 1.1e-18 66.6 0.9 1.1e-07 31.5 0.0 5.4 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EEQ29853.1 - 4.1e-10 39.0 0.0 0.013 15.0 0.0 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EEQ29853.1 - 3.4e-09 36.4 2.7 0.12 12.6 0.3 5.4 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EEQ29853.1 - 5.8e-07 29.3 7.1 0.0091 15.9 0.0 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EEQ29853.1 - 2.3e-06 27.1 4.7 0.0023 17.6 0.0 5.0 5 0 0 5 5 5 1 Kelch motif BTB PF00651.26 EEQ29853.1 - 0.15 12.0 0.0 0.54 10.2 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain mRNA_triPase PF02940.10 EEQ29854.1 - 4.7e-51 173.5 0.0 8.2e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain WD40 PF00400.27 EEQ29855.1 - 1e-23 82.3 8.9 2.3e-08 33.6 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat TFIIA PF03153.8 EEQ29855.1 - 1 9.2 20.3 2 8.1 14.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 EEQ29855.1 - 8.5 4.5 6.7 12 4.0 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein CTP_transf_2 PF01467.21 EEQ29856.1 - 0.00013 22.0 0.6 0.0016 18.5 0.4 2.3 1 1 0 1 1 1 1 Cytidylyltransferase F-box PF00646.28 EEQ29857.1 - 0.24 11.0 0.1 0.24 11.0 0.1 3.1 3 0 0 3 3 3 0 F-box domain Fungal_trans_2 PF11951.3 EEQ29858.1 - 0.00017 20.3 0.2 0.00028 19.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain UbiA PF01040.13 EEQ29859.1 - 1.4e-29 103.0 19.1 1.4e-29 103.0 13.3 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family PQ-loop PF04193.9 EEQ29860.1 - 8.5e-20 70.0 7.0 2.2e-12 46.3 1.0 2.9 2 0 0 2 2 2 2 PQ loop repeat UPF0239 PF06783.6 EEQ29860.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF3464 PF11947.3 EEQ29860.1 - 5 6.5 6.2 2.6 7.5 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Med8 PF10232.4 EEQ29861.1 - 4e-38 131.1 2.5 7.1e-38 130.3 1.7 1.5 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 TMEM154 PF15102.1 EEQ29862.1 - 0.0026 17.4 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 EEQ29862.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 EEQ29862.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2849 PF11011.3 EEQ29866.1 - 0.12 12.6 0.4 0.35 11.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) Abhydrolase_5 PF12695.2 EEQ29867.1 - 3.7e-07 29.9 0.0 7.4e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ29867.1 - 6.2e-05 22.9 0.0 0.0014 18.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ29867.1 - 0.00049 19.3 0.0 0.03 13.5 0.0 2.8 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EEQ29867.1 - 0.019 14.5 0.0 0.91 9.0 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EEQ29867.1 - 0.049 13.0 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TMF_TATA_bd PF12325.3 EEQ29868.1 - 0.0021 17.7 1.9 0.0021 17.7 1.3 3.8 3 2 1 4 4 4 1 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 EEQ29868.1 - 0.01 15.0 3.4 0.018 14.2 0.4 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Phlebovirus_NSM PF07246.6 EEQ29868.1 - 0.029 13.5 6.2 0.12 11.4 1.4 2.3 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Med21 PF11221.3 EEQ29868.1 - 0.076 12.9 10.3 0.13 12.1 0.0 4.0 3 2 0 3 3 3 0 Subunit 21 of Mediator complex PA26 PF04636.8 EEQ29868.1 - 0.086 11.5 0.7 0.13 10.8 0.5 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Spc7 PF08317.6 EEQ29868.1 - 0.39 9.3 14.4 0.28 9.8 3.8 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4600 PF15372.1 EEQ29868.1 - 0.41 10.8 8.7 0.064 13.4 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Phage_GP20 PF06810.6 EEQ29868.1 - 0.51 9.7 8.7 0.49 9.8 1.2 3.1 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF4140 PF13600.1 EEQ29868.1 - 0.65 10.4 10.0 1.4 9.4 0.2 4.0 4 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Nup54 PF13874.1 EEQ29868.1 - 0.78 9.3 9.0 2 8.0 0.5 2.9 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 TMPIT PF07851.8 EEQ29868.1 - 0.91 8.5 2.6 26 3.7 1.0 2.4 2 0 0 2 2 2 0 TMPIT-like protein ADIP PF11559.3 EEQ29868.1 - 0.93 9.3 18.4 2.5 7.9 0.4 3.9 3 2 0 3 3 3 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EEQ29868.1 - 3.7 6.5 13.4 1.2 8.1 3.4 2.6 1 1 1 2 2 2 0 Autophagy protein Apg6 EzrA PF06160.7 EEQ29868.1 - 4.7 5.2 12.5 0.31 9.1 3.9 2.3 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.2 EEQ29868.1 - 7 6.5 20.0 0.2 11.5 2.8 3.0 3 1 0 3 3 3 0 Tropomyosin like Pkinase PF00069.20 EEQ29869.1 - 2.2e-23 82.7 0.0 6e-23 81.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29869.1 - 5.5e-10 38.7 0.2 2.4e-09 36.6 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PC_rep PF01851.17 EEQ29870.1 - 5.4e-36 120.8 21.4 2.4e-09 36.9 0.0 9.9 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EEQ29870.1 - 3.8e-19 68.7 0.6 8.7e-14 51.5 0.0 3.7 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EEQ29870.1 - 2.8e-09 37.1 1.8 5.7e-06 26.6 0.0 4.5 4 1 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EEQ29870.1 - 2.2e-08 33.5 0.1 1.1 9.4 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 EEQ29870.1 - 0.0064 16.8 2.0 0.88 10.2 0.0 3.8 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Acyl-CoA_dh_1 PF00441.19 EEQ29871.1 - 1e-40 139.2 0.2 1.7e-40 138.6 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ29871.1 - 6.3e-20 70.4 0.1 1.1e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEQ29871.1 - 1.5e-18 67.4 0.0 3.4e-18 66.2 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 EEQ29871.1 - 2.1e-14 53.0 0.9 4.2e-14 52.1 0.6 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 EEQ29871.1 - 1e-07 32.2 0.1 1.7e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TALPID3 PF15324.1 EEQ29871.1 - 0.37 8.0 1.3 0.51 7.6 0.9 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Spt5-NGN PF03439.8 EEQ29872.1 - 2e-23 81.9 0.0 3.5e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 EEQ29872.1 - 3.5e-23 82.3 48.3 3.3e-22 79.2 21.7 3.5 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 EEQ29872.1 - 1.6e-16 60.6 12.5 1.6e-16 60.6 8.6 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EEQ29872.1 - 1.1e-08 34.4 15.6 0.0026 17.4 0.0 4.7 4 0 0 4 4 4 3 KOW motif DUF1506 PF07405.6 EEQ29872.1 - 0.1 12.5 0.2 1 9.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1506) CS PF04969.11 EEQ29873.1 - 1.6e-16 60.5 0.0 3.3e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 CS domain DUF4404 PF14357.1 EEQ29873.1 - 0.82 10.1 4.1 0.87 10.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) GET2 PF08690.5 EEQ29873.1 - 8.9 5.4 8.5 0.064 12.4 0.5 1.4 2 0 0 2 2 2 0 GET complex subunit GET2 Pkinase PF00069.20 EEQ29874.1 - 3.9e-20 72.0 0.1 3e-10 39.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29874.1 - 2.5e-05 23.4 0.6 0.072 12.1 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Anoctamin PF04547.7 EEQ29875.1 - 1.2e-117 393.3 3.0 1.6e-117 392.9 2.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Clathrin-link PF09268.5 EEQ29875.1 - 1.1 8.3 2.8 17 4.5 0.0 3.5 4 0 0 4 4 4 0 Clathrin, heavy-chain linker bZIP_1 PF00170.16 EEQ29876.1 - 5.5e-07 29.4 10.2 2.7e-06 27.2 7.1 2.1 1 1 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 EEQ29876.1 - 0.011 15.4 0.4 0.023 14.4 0.3 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF501 PF04417.7 EEQ29876.1 - 0.019 14.8 0.8 0.046 13.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) bZIP_2 PF07716.10 EEQ29876.1 - 0.23 11.3 11.0 11 5.9 7.6 3.1 2 1 0 2 2 2 0 Basic region leucine zipper Suf PF05843.9 EEQ29876.1 - 0.7 9.5 5.7 1.1 8.9 4.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Actin PF00022.14 EEQ29877.1 - 1.2e-45 155.6 0.0 1.5e-22 79.5 0.0 3.1 2 1 0 2 2 2 2 Actin DASH_Dad4 PF08650.5 EEQ29878.1 - 1.6e-13 50.3 3.1 1.6e-13 50.3 2.1 1.4 2 0 0 2 2 2 1 DASH complex subunit Dad4 DUF368 PF04018.8 EEQ29878.1 - 0.067 12.3 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF368) GM_CSF PF01109.12 EEQ29878.1 - 0.1 12.5 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor YL1_C PF08265.6 EEQ29879.1 - 3.8e-16 58.3 0.1 6e-16 57.6 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain TFIIA PF03153.8 EEQ29879.1 - 0.69 9.7 4.2 0.72 9.6 2.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Got1 PF04178.7 EEQ29880.1 - 1.7e-16 60.3 6.1 2.1e-16 60.0 4.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1616 PF07760.6 EEQ29880.1 - 0.035 13.2 2.2 0.04 13.0 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Profilin PF00235.14 EEQ29881.1 - 7.6e-35 119.6 0.0 9.5e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 Profilin CHASE4 PF05228.8 EEQ29881.1 - 0.027 14.0 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 CHASE4 domain SSP160 PF06933.6 EEQ29882.1 - 1.2 7.0 11.8 2.3 6.0 8.2 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 EEQ29882.1 - 7.4 4.1 6.0 13 3.3 4.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sec63 PF02889.11 EEQ29883.1 - 2.1e-150 500.2 0.0 1.5e-92 310.2 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EEQ29883.1 - 5.6e-55 185.4 1.1 2.1e-28 98.9 0.6 3.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EEQ29883.1 - 9e-17 61.4 0.0 8.8e-08 32.1 0.1 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ29883.1 - 8.8e-16 57.5 0.0 3.7e-07 29.9 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEQ29883.1 - 8.6e-08 32.3 0.1 0.016 15.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain SNF2_N PF00176.18 EEQ29883.1 - 0.00035 19.4 0.6 0.24 10.1 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_19 PF13245.1 EEQ29883.1 - 0.00039 20.1 0.1 1 9.1 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain PhoH PF02562.11 EEQ29883.1 - 0.0013 17.9 0.0 0.39 9.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein FtsK_SpoIIIE PF01580.13 EEQ29883.1 - 0.0027 17.2 0.2 0.048 13.1 0.1 2.7 2 1 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EEQ29883.1 - 0.013 14.9 0.0 5.6 6.3 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_10 PF12846.2 EEQ29883.1 - 0.041 13.3 0.0 7.7 5.8 0.0 3.7 4 0 0 4 4 4 0 AAA-like domain Cupin_1 PF00190.17 EEQ29886.1 - 8.7e-26 90.0 0.0 1e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EEQ29886.1 - 8.2e-21 73.2 0.9 4.7e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EEQ29886.1 - 1.5e-06 27.4 0.3 0.0021 17.4 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EEQ29886.1 - 2e-05 24.3 0.8 0.015 14.9 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EEQ29886.1 - 0.029 13.9 0.0 0.69 9.4 0.0 2.5 1 1 1 2 2 2 0 Cupin A2L_zn_ribbon PF08792.5 EEQ29888.1 - 0.72 9.3 3.2 0.99 8.9 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-RanBP PF00641.13 EEQ29888.1 - 3.3 6.8 6.1 1.3 8.2 1.0 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Synaptobrevin PF00957.16 EEQ29889.1 - 7.3e-14 51.1 0.2 1.1e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EEQ29889.1 - 1.7e-13 49.9 0.0 2.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tbf5 PF06331.7 EEQ29889.1 - 0.067 12.9 0.3 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 MFS_1 PF07690.11 EEQ29890.1 - 5.4e-19 68.1 52.2 7.7e-11 41.2 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EEQ29890.1 - 3.3e-05 23.8 15.3 0.1 12.6 2.2 3.8 4 0 0 4 4 4 3 Protein of unknown function (DUF1228) Ras PF00071.17 EEQ29891.1 - 6.2e-29 100.4 0.0 9.9e-28 96.5 0.0 2.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEQ29891.1 - 2.2e-12 47.4 0.0 5.5e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ29891.1 - 1.8e-08 33.8 0.0 3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.1 EEQ29891.1 - 0.0018 18.3 0.5 0.036 14.0 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EEQ29891.1 - 0.0073 16.2 0.8 0.056 13.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain Gtr1_RagA PF04670.7 EEQ29891.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ29891.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 EEQ29891.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EEQ29891.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EEQ29891.1 - 0.02 14.1 0.1 0.042 13.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EEQ29891.1 - 0.04 13.4 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EEQ29891.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain FMN_dh PF01070.13 EEQ29892.1 - 1.9e-120 401.9 0.1 2.4e-120 401.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEQ29892.1 - 4e-20 71.3 0.0 8.7e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EEQ29892.1 - 4.1e-07 29.2 0.0 6.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EEQ29892.1 - 1.8e-06 27.3 0.0 2.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEQ29892.1 - 0.0004 19.3 0.8 0.0012 17.8 0.1 2.1 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EEQ29892.1 - 0.011 15.0 0.8 0.58 9.3 0.1 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 EEQ29892.1 - 0.068 12.2 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Metallophos PF00149.23 EEQ29893.1 - 3.1e-12 46.3 5.7 6.4e-12 45.2 3.9 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ29893.1 - 2.3e-09 37.2 0.0 6.3e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.1 EEQ29893.1 - 0.021 13.1 0.0 0.026 12.8 0.0 1.1 1 0 0 1 1 1 0 MutL protein Pkinase PF00069.20 EEQ29894.1 - 6.6e-40 136.8 0.1 4.3e-25 88.3 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29894.1 - 1.8e-13 50.2 0.1 4.5e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Bud13 PF09736.4 EEQ29895.1 - 5.5e-44 149.9 0.3 5.5e-44 149.9 0.2 3.1 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex PEP-utilisers_N PF05524.8 EEQ29896.1 - 0.0035 17.1 0.1 0.0064 16.2 0.1 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Bap31 PF05529.7 EEQ29896.1 - 0.072 12.5 1.4 0.1 12.0 1.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Prefoldin_2 PF01920.15 EEQ29896.1 - 0.3 10.8 3.0 0.6 9.8 2.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit FlaC_arch PF05377.6 EEQ29896.1 - 0.44 10.4 3.8 0.16 11.8 0.3 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DNA_binding_1 PF01035.15 EEQ29897.1 - 2.7e-22 78.3 0.0 3.6e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Fungal_trans_2 PF11951.3 EEQ29899.1 - 2.2e-102 342.5 6.3 2.5e-102 342.3 4.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Brr6_like_C_C PF10104.4 EEQ29900.1 - 2.5e-44 150.0 0.7 3.3e-44 149.6 0.5 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ninjurin PF04923.7 EEQ29900.1 - 0.14 11.8 0.7 0.33 10.7 0.5 1.6 1 1 0 1 1 1 0 Ninjurin AA_permease PF00324.16 EEQ29901.1 - 6.6e-118 394.0 46.3 7.5e-118 393.8 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ29901.1 - 7.2e-27 93.9 51.7 9.1e-27 93.6 35.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ29902.1 - 1.7e-44 152.0 44.1 4e-44 150.8 30.6 1.5 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 EEQ29903.1 - 2.8e-18 66.0 0.0 3.8e-12 45.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29903.1 - 0.00079 18.5 0.0 0.0032 16.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase polyprenyl_synt PF00348.12 EEQ29904.1 - 4e-34 117.6 0.0 6.7e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EEQ29904.1 - 4.3e-06 26.1 0.2 0.013 14.7 0.0 2.4 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain ANTAR PF03861.9 EEQ29904.1 - 0.00045 19.7 0.0 0.00083 18.8 0.0 1.4 1 0 0 1 1 1 1 ANTAR domain DUF713 PF05218.9 EEQ29904.1 - 0.02 14.6 0.1 0.38 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF713) Peptidase_M20 PF01546.23 EEQ29905.1 - 0.00012 21.6 0.1 0.0002 20.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEQ29905.1 - 0.038 13.7 0.1 0.13 12.0 0.1 1.9 1 1 0 1 1 1 0 Peptidase dimerisation domain HNH_2 PF13391.1 EEQ29906.1 - 5.6e-15 54.8 0.0 1.1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease GRIP PF01465.15 EEQ29908.1 - 1.6e-15 56.3 0.6 3.9e-15 55.0 0.4 1.6 1 0 0 1 1 1 1 GRIP domain Acetyltransf_1 PF00583.19 EEQ29908.1 - 3e-15 55.9 0.0 6.5e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EEQ29908.1 - 7.4e-08 32.6 0.0 2.8e-07 30.8 0.0 2.1 2 0 0 2 2 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ29908.1 - 4.8e-07 29.8 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ29908.1 - 6.6e-07 28.9 0.0 2.3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Reo_sigmaC PF04582.7 EEQ29908.1 - 0.00011 21.5 51.1 0.13 11.4 0.2 6.5 3 2 3 6 6 6 5 Reovirus sigma C capsid protein DUF869 PF05911.6 EEQ29908.1 - 0.00017 19.9 119.2 0.00019 19.8 13.5 5.4 2 1 1 4 4 4 2 Plant protein of unknown function (DUF869) Acetyltransf_10 PF13673.1 EEQ29908.1 - 0.0006 19.9 0.0 0.0017 18.4 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_13 PF13166.1 EEQ29908.1 - 0.0018 16.8 15.0 0.0018 16.8 10.4 5.6 3 1 3 6 6 6 4 AAA domain TPR_MLP1_2 PF07926.7 EEQ29908.1 - 0.0062 16.2 120.2 0.029 14.1 0.0 10.7 4 2 4 8 8 7 1 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 EEQ29908.1 - 0.0076 16.1 32.9 0.0076 16.1 22.8 9.4 4 2 8 12 12 12 1 Tropomyosin like Filament PF00038.16 EEQ29908.1 - 0.032 13.6 120.5 0.19 11.1 34.2 6.3 3 2 1 5 5 5 0 Intermediate filament protein Acetyltransf_CG PF14542.1 EEQ29908.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase IncA PF04156.9 EEQ29908.1 - 0.12 12.0 149.7 0.034 13.7 17.6 8.7 4 2 5 9 9 8 0 IncA protein CENP-F_leu_zip PF10473.4 EEQ29908.1 - 0.12 12.2 150.6 0.022 14.6 3.3 9.3 4 2 6 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EEQ29908.1 - 0.25 10.5 122.6 0.086 12.0 11.9 7.6 4 2 3 7 7 7 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 EEQ29908.1 - 0.94 9.9 0.0 0.94 9.9 0.0 14.4 5 2 9 14 14 12 0 N-terminal domain of unknown function (DUF4140) Myosin_tail_1 PF01576.14 EEQ29908.1 - 6.6 4.3 147.4 0.16 9.6 22.3 5.0 2 1 2 4 4 4 0 Myosin tail DUF2296 PF10058.4 EEQ29909.1 - 1.7e-18 66.0 0.1 2.8e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) cNMP_binding PF00027.24 EEQ29910.1 - 3.5e-42 142.1 0.2 8.1e-23 80.0 0.0 4.9 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EEQ29910.1 - 1.9e-17 63.8 11.5 3.3e-17 63.0 4.9 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase DAO PF01266.19 EEQ29911.1 - 1.8e-33 115.9 0.0 2.2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ29911.1 - 5.6e-05 23.1 0.0 0.033 14.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ29911.1 - 0.00011 22.0 0.0 0.0037 17.0 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEQ29911.1 - 0.00022 21.2 0.0 0.00064 19.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EEQ29911.1 - 0.004 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Saccharop_dh PF03435.13 EEQ29911.1 - 0.0079 15.2 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase K_oxygenase PF13434.1 EEQ29911.1 - 0.0091 14.9 0.0 0.028 13.3 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.16 EEQ29911.1 - 0.03 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 ThiF family Abhydrolase_6 PF12697.2 EEQ29911.1 - 0.078 12.8 0.1 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Pyr_redox_3 PF13738.1 EEQ29911.1 - 0.094 12.7 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ29911.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_33 PF10017.4 EEQ29912.1 - 1.7e-14 53.7 0.0 2.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_32 PF13679.1 EEQ29912.1 - 0.031 13.9 0.0 0.18 11.4 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ29912.1 - 0.096 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ29912.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.3 EEQ29913.1 - 3.1e-19 68.8 0.0 7.2e-18 64.3 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EEQ29915.1 - 0.00019 21.5 1.8 0.21 11.9 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ29915.1 - 1.3 9.4 10.5 5.7 7.4 0.3 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type DUF2737 PF10930.3 EEQ29916.1 - 0.13 11.8 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) ATP-synt_Eps PF04627.8 EEQ29917.1 - 0.012 15.1 0.2 0.032 13.7 0.0 2.0 2 1 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain p450 PF00067.17 EEQ29918.1 - 1.3e-56 192.0 0.0 1.1e-45 156.0 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 ISN1 PF06437.6 EEQ29919.1 - 1.6e-172 573.8 0.2 8.6e-167 554.9 0.0 2.0 1 1 0 2 2 2 2 IMP-specific 5'-nucleotidase RasGEF_N_2 PF14663.1 EEQ29919.1 - 0.037 13.9 0.3 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Med17 PF10156.4 EEQ29920.1 - 4.3e-113 378.0 0.3 5.3e-113 377.7 0.2 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.15 EEQ29921.1 - 4.8e-170 563.8 0.2 4.6e-123 409.6 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 EEQ29921.1 - 0.093 11.4 0.1 0.49 9.1 0.1 2.0 2 0 0 2 2 2 0 ATP-NAD kinase Glyco_hydro_76 PF03663.9 EEQ29922.1 - 1.7e-152 508.1 6.9 2.2e-152 507.7 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EEQ29922.1 - 0.57 9.1 6.8 1 8.3 0.1 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 MARVEL PF01284.18 EEQ29923.1 - 0.00017 21.4 2.1 0.28 10.9 0.1 2.1 2 0 0 2 2 2 2 Membrane-associating domain DnaJ PF00226.26 EEQ29924.1 - 1.5e-19 69.5 1.8 3.3e-19 68.3 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain Complex1_LYR PF05347.10 EEQ29925.1 - 1.2e-06 28.2 0.1 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ29925.1 - 2.2e-06 27.7 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like RRM_5 PF13893.1 EEQ29926.1 - 2e-10 40.3 0.0 5.5e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ29926.1 - 6.8e-10 38.4 0.0 1.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ29926.1 - 4.7e-06 26.4 0.0 8.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ29926.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.5 EEQ29927.1 - 2.8e-28 97.6 0.1 4.2e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EEQ29927.1 - 6.5e-18 65.0 0.0 1.2e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ29927.1 - 5.9e-16 58.4 0.0 8.9e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ29927.1 - 9.1e-14 51.4 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ29927.1 - 1.6e-12 47.6 0.0 3.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEQ29927.1 - 3.1e-11 42.8 0.0 4.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EEQ29927.1 - 8.6e-11 42.1 0.0 2.1e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ29927.1 - 1.7e-10 41.4 0.0 3.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ29927.1 - 2.9e-09 36.4 0.0 4.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEQ29927.1 - 5e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EEQ29927.1 - 1.4e-05 24.6 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EEQ29927.1 - 0.00024 20.5 0.0 0.0008 18.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EEQ29927.1 - 0.00093 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EEQ29927.1 - 0.002 17.7 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EEQ29927.1 - 0.014 15.0 0.4 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ29927.1 - 0.02 13.9 0.0 0.056 12.4 0.0 1.8 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EEQ29927.1 - 0.025 13.5 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 EEQ29927.1 - 0.092 13.5 0.0 0.31 11.8 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EEQ29927.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase zf-MYND PF01753.13 EEQ29928.1 - 3.6e-08 33.1 12.6 3.6e-08 33.1 8.7 2.7 2 1 0 2 2 2 1 MYND finger Peptidase_S8 PF00082.17 EEQ29929.1 - 1.1e-31 110.0 6.2 1.4e-31 109.7 4.3 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ29929.1 - 0.0041 17.6 0.0 0.029 14.9 0.0 2.1 1 1 1 2 2 2 1 Peptidase inhibitor I9 MFS_1 PF07690.11 EEQ29930.1 - 1.9e-42 145.2 49.4 5e-42 143.8 34.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily WTF PF03303.8 EEQ29930.1 - 0.37 10.1 5.4 0.76 9.1 3.7 1.5 1 0 0 1 1 1 0 WTF protein Fungal_trans PF04082.13 EEQ29931.1 - 6.3e-16 58.0 0.0 9.9e-16 57.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ29931.1 - 2.2e-08 33.8 9.4 3.7e-08 33.1 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.18 EEQ29932.1 - 1.3e-58 198.5 0.0 1.9e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EEQ29932.1 - 9.5e-21 73.3 0.2 3.9e-20 71.4 0.0 2.0 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EEQ29932.1 - 9.8e-08 31.7 2.5 1.5e-05 24.4 1.7 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EEQ29932.1 - 0.021 15.0 0.5 0.065 13.5 0.1 1.9 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Amidohydro_1 PF01979.15 EEQ29933.1 - 3.6e-36 125.4 0.0 4.6e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EEQ29933.1 - 2e-07 30.5 0.1 5.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.17 EEQ29933.1 - 1.9e-06 27.0 0.0 3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 EEQ29933.1 - 9e-05 22.6 0.2 0.0015 18.6 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EEQ29933.1 - 0.0047 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Toxin_29 PF08116.6 EEQ29933.1 - 0.067 12.9 3.0 0.11 12.2 0.4 2.3 2 0 0 2 2 2 0 PhTx neurotoxin family Pkinase PF00069.20 EEQ29934.1 - 5.7e-06 25.6 0.0 1.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ29934.1 - 0.098 12.3 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family GDC-P PF02347.11 EEQ29935.1 - 2.8e-170 566.6 0.0 3.8e-157 523.3 0.0 2.4 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EEQ29935.1 - 1.1e-08 34.5 0.1 2.1e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEQ29935.1 - 0.0011 17.7 0.2 0.0033 16.2 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ29935.1 - 0.0021 17.1 0.0 0.0039 16.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.16 EEQ29935.1 - 0.0059 15.4 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III SLA_LP_auto_ag PF05889.8 EEQ29935.1 - 0.13 10.7 0.0 4.4 5.6 0.0 2.1 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Pyridoxal_deC PF00282.14 EEQ29936.1 - 1e-107 359.8 0.0 4.1e-107 357.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EEQ29936.1 - 0.012 14.7 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Abhydrolase_6 PF12697.2 EEQ29937.1 - 2.1e-19 70.3 0.0 2.8e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ29937.1 - 1.6e-11 44.1 0.1 2e-11 43.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ29937.1 - 0.00059 19.4 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEQ29937.1 - 0.047 13.5 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Thioesterase PF00975.15 EEQ29937.1 - 0.17 12.1 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain MBOAT_2 PF13813.1 EEQ29938.1 - 3.2e-16 59.1 0.2 8.1e-16 57.8 0.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glyco_hydro_65m PF03632.10 EEQ29939.1 - 1.1e-79 267.8 0.8 6.2e-79 265.3 0.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EEQ29939.1 - 1.8e-45 155.2 0.1 2.7e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EEQ29939.1 - 0.00022 21.2 0.9 0.00049 20.1 0.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain APH PF01636.18 EEQ29940.1 - 1.6e-09 37.8 0.1 2.9e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ29940.1 - 9.2e-05 22.1 0.1 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ29940.1 - 0.12 11.4 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain SMC_Nse1 PF07574.8 EEQ29941.1 - 2.1e-39 135.2 0.1 2.7e-39 134.8 0.1 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EEQ29941.1 - 3.4e-11 42.9 9.1 6.5e-11 42.0 6.3 1.5 1 0 0 1 1 1 1 RING-like domain HTH_27 PF13463.1 EEQ29941.1 - 0.012 15.8 0.1 0.22 11.8 0.0 2.8 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf-rbx1 PF12678.2 EEQ29941.1 - 0.013 15.5 2.4 0.024 14.7 1.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger PaaX PF07848.7 EEQ29941.1 - 0.017 15.0 0.2 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 PaaX-like protein Baculo_IE-1 PF05290.6 EEQ29941.1 - 0.029 14.0 4.9 0.049 13.3 2.0 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.1 EEQ29941.1 - 0.061 13.1 7.7 0.11 12.3 5.3 1.4 1 0 0 1 1 1 0 Ring finger domain RQC PF09382.5 EEQ29941.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 RQC domain zf-Apc11 PF12861.2 EEQ29941.1 - 0.1 12.4 3.1 0.18 11.6 2.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 EEQ29941.1 - 0.23 11.4 5.1 0.64 10.0 3.6 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 EEQ29941.1 - 0.25 11.3 5.1 0.78 9.7 3.3 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EEQ29941.1 - 1.4 8.6 8.2 3.4 7.4 5.7 1.7 1 1 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.17 EEQ29941.1 - 1.9 8.2 9.4 0.14 11.8 2.5 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 EEQ29941.1 - 2.5 8.3 8.2 6.8 6.9 5.0 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-C3HC4_3 PF13920.1 EEQ29941.1 - 4.4 7.0 8.2 46 3.7 5.7 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ29941.1 - 7.9 6.2 8.3 27 4.5 5.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DAO PF01266.19 EEQ29942.1 - 4.4e-36 124.5 0.2 5.6e-36 124.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ29942.1 - 0.0021 18.0 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ29942.1 - 0.0033 17.3 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ29942.1 - 0.016 15.6 0.1 0.057 13.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ29942.1 - 0.028 14.2 0.1 0.075 12.8 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4066 PF13278.1 EEQ29943.1 - 3.9e-27 94.5 0.0 4.3e-26 91.1 0.0 2.0 1 1 1 2 2 2 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEQ29943.1 - 1.4e-15 57.0 0.0 1.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EEQ29943.1 - 0.025 14.0 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Imm11 PF15563.1 EEQ29944.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 11 AA_permease_2 PF13520.1 EEQ29946.1 - 1.1e-67 228.5 36.1 1.3e-67 228.2 25.0 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM51 PF15345.1 EEQ29946.1 - 0.15 11.7 0.3 0.3 10.7 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 adh_short PF00106.20 EEQ29947.1 - 1e-30 106.8 0.2 1.4e-30 106.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ29947.1 - 3.2e-12 46.7 0.0 4.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ29947.1 - 5.3e-11 42.4 0.1 8.3e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ29947.1 - 0.0034 16.8 0.0 0.008 15.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEQ29947.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding TrkA_N PF02254.13 EEQ29947.1 - 0.026 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 EEQ29947.1 - 0.077 11.6 0.0 0.11 11.1 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CBFD_NFYB_HMF PF00808.18 EEQ29948.1 - 1.5e-18 66.5 0.5 1.5e-18 66.5 0.4 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ29948.1 - 0.00073 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EEQ29948.1 - 0.095 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated YolD PF08863.5 EEQ29948.1 - 0.66 9.8 3.1 0.41 10.5 0.8 1.6 2 0 0 2 2 2 0 YolD-like protein Actin PF00022.14 EEQ29949.1 - 8.7e-10 37.5 0.0 1.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Actin SPRY PF00622.23 EEQ29950.1 - 0.00056 19.9 0.0 0.0036 17.3 0.0 2.3 3 0 0 3 3 3 1 SPRY domain Amidase PF01425.16 EEQ29951.1 - 1.8e-105 353.3 0.2 2.6e-105 352.8 0.1 1.2 1 0 0 1 1 1 1 Amidase Snf7 PF03357.16 EEQ29952.1 - 0.0012 18.3 8.1 0.0014 18.0 5.6 1.1 1 0 0 1 1 1 1 Snf7 DUF3829 PF12889.2 EEQ29952.1 - 0.012 14.8 4.7 0.016 14.4 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF4515 PF14988.1 EEQ29952.1 - 2.1 7.9 7.1 0.43 10.2 2.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) bZIP_2 PF07716.10 EEQ29954.1 - 3.9e-08 32.9 15.3 3.9e-08 32.9 10.6 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EEQ29954.1 - 1.2e-05 25.1 17.0 2.9e-05 23.9 11.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor DUF869 PF05911.6 EEQ29954.1 - 0.00028 19.2 4.3 0.00038 18.8 2.9 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Striatin PF08232.7 EEQ29954.1 - 0.00082 19.6 7.7 0.00082 19.6 5.3 1.7 1 1 0 1 1 1 1 Striatin family bZIP_Maf PF03131.12 EEQ29954.1 - 0.0041 17.3 12.6 0.0088 16.3 8.7 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor CENP-H PF05837.7 EEQ29954.1 - 0.0094 16.1 3.1 0.0094 16.1 2.1 2.2 1 1 1 2 2 2 1 Centromere protein H (CENP-H) DUF972 PF06156.8 EEQ29954.1 - 0.057 13.7 1.7 0.12 12.6 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 EEQ29954.1 - 0.066 12.2 8.9 0.096 11.7 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 EEQ29954.1 - 0.58 9.2 8.2 1 8.5 5.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF724 PF05266.9 EEQ29954.1 - 0.86 9.1 7.1 1.4 8.5 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Metallophos PF00149.23 EEQ29956.1 - 4.4e-10 39.2 0.1 7.9e-10 38.4 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EEQ29956.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain TetM_leader PF08076.6 EEQ29956.1 - 0.13 11.8 2.2 0.41 10.2 1.5 1.8 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide Transket_pyr PF02779.19 EEQ29957.1 - 5.9e-47 159.4 0.0 8.7e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEQ29957.1 - 1.9e-34 118.2 0.0 5.1e-34 116.8 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Glyco_hydro_43 PF04616.9 EEQ29958.1 - 4.7e-50 170.2 4.9 1.9e-49 168.2 3.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 zf-met PF12874.2 EEQ29959.1 - 0.0046 17.1 0.4 0.0082 16.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EEQ29959.1 - 0.0058 16.8 1.2 0.011 15.9 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ29959.1 - 0.01 16.0 0.3 0.021 15.1 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ29959.1 - 0.045 13.6 0.3 0.045 13.6 0.2 1.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ29959.1 - 0.22 11.6 3.4 0.37 11.0 2.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF1691 PF07950.6 EEQ29960.1 - 2.9e-47 159.1 5.6 5.1e-32 110.0 2.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF1469 PF07332.6 EEQ29960.1 - 0.036 13.8 0.9 0.036 13.8 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) TRM PF02005.11 EEQ29961.1 - 1.6e-108 363.0 0.0 4.1e-93 312.3 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.1 EEQ29961.1 - 0.0029 17.2 0.0 0.008 15.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EEQ29961.1 - 0.0052 16.3 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF2067 PF09840.4 EEQ29961.1 - 0.016 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Methyltransf_26 PF13659.1 EEQ29961.1 - 0.017 15.1 0.1 0.042 13.8 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ29961.1 - 0.052 14.1 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.1 EEQ29962.1 - 1.4e-20 74.1 0.0 3.4e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EEQ29962.1 - 2.7e-19 69.6 0.0 5.8e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EEQ29962.1 - 1.5e-17 63.4 0.1 2.9e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EEQ29962.1 - 2.1e-11 43.7 0.0 4.9e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EEQ29962.1 - 2.4e-05 24.3 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ29962.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1031 PF06275.6 EEQ29962.1 - 0.095 12.7 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Acyl_transf_1 PF00698.16 EEQ29963.1 - 5.2e-88 295.4 0.0 2.2e-84 283.4 0.0 3.8 3 1 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EEQ29963.1 - 5.8e-40 135.4 0.1 2e-39 133.7 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EEQ29963.1 - 1.4e-31 108.0 0.7 3.5e-31 106.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EEQ29963.1 - 3e-20 72.3 0.0 1e-19 70.6 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EEQ29963.1 - 0.00054 19.2 1.6 0.0083 15.3 1.1 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase DUF3586 PF12131.3 EEQ29964.1 - 0.01 15.8 0.4 0.015 15.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Gamma-thionin PF00304.15 EEQ29964.1 - 0.048 13.6 1.7 0.069 13.1 1.2 1.2 1 0 0 1 1 1 0 Gamma-thionin family SLR1-BP PF07333.7 EEQ29964.1 - 0.11 12.8 1.3 0.15 12.3 0.9 1.2 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) His_Phos_2 PF00328.17 EEQ29965.1 - 1.3e-114 383.1 0.1 1.6e-114 382.8 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EEQ29965.1 - 7.6e-06 25.5 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EEQ29966.1 - 5.4e-83 277.7 0.6 7.8e-83 277.2 0.4 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EEQ29966.1 - 5.3e-18 64.1 21.8 0.00033 20.4 0.2 9.4 10 0 0 10 10 10 5 WD domain, G-beta repeat RCR PF12273.3 EEQ29967.1 - 0.0025 18.3 1.3 0.0056 17.2 0.8 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red ATG27 PF09451.5 EEQ29967.1 - 0.13 11.4 2.1 0.18 11.0 1.5 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 P12 PF12669.2 EEQ29967.1 - 0.18 12.0 1.7 0.3 11.2 1.2 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF4307 PF14155.1 EEQ29967.1 - 0.53 10.1 2.3 0.81 9.4 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) TMEMspv1-c74-12 PF11044.3 EEQ29967.1 - 0.67 9.5 2.9 1.1 8.8 2.0 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PTR2 PF00854.16 EEQ29969.1 - 6.3e-33 114.0 8.5 9.4e-33 113.4 5.9 1.3 1 0 0 1 1 1 1 POT family ATP-grasp_4 PF13535.1 EEQ29970.1 - 7.4e-21 74.7 0.0 2.3e-19 69.8 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEQ29970.1 - 1.3e-08 34.5 0.0 2.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EEQ29970.1 - 6.4e-06 25.1 0.0 0.00094 18.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EEQ29970.1 - 0.0049 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EEQ29970.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EEQ29970.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATPgrasp_TupA PF14305.1 EEQ29970.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 TupA-like ATPgrasp XPG_I_2 PF12813.2 EEQ29971.1 - 8.6e-80 267.7 0.0 1.4e-79 267.0 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EEQ29971.1 - 0.093 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 XPG I-region IBR PF01485.16 EEQ29972.1 - 1.4e-10 40.8 40.3 1.4e-07 31.3 4.5 3.6 3 1 0 3 3 3 2 IBR domain AUX_IAA PF02309.11 EEQ29972.1 - 1.2 8.8 5.1 1.9 8.1 3.5 1.2 1 0 0 1 1 1 0 AUX/IAA family TFIIF_alpha PF05793.7 EEQ29973.1 - 4.6e-06 25.2 63.8 4.6e-06 25.2 44.2 3.2 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.14 EEQ29974.1 - 4.4e-10 39.3 0.0 8.2e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEQ29974.1 - 0.0049 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 EEQ29974.1 - 0.047 12.4 0.1 0.76 8.5 0.0 2.2 2 0 0 2 2 2 0 Poly(A) polymerase central domain Rep-A_N PF04057.7 EEQ29975.1 - 0.00034 20.3 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain AA_permease_2 PF13520.1 EEQ29976.1 - 2.6e-43 148.1 45.5 3.3e-43 147.8 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ29976.1 - 3.5e-23 81.6 36.5 5e-23 81.1 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF383 PF04063.9 EEQ29977.1 - 2.1e-68 229.6 0.0 1.4e-67 226.9 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EEQ29977.1 - 3.9e-21 74.3 0.7 1.6e-20 72.3 0.5 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Inositol_P PF00459.20 EEQ29978.1 - 1.8e-51 175.0 0.1 5e-51 173.5 0.1 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.20 EEQ29979.1 - 3.7e-28 98.3 0.0 1.3e-27 96.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29979.1 - 1.3e-07 30.9 0.2 0.015 14.3 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ29979.1 - 0.037 12.8 0.1 0.083 11.6 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF676 PF05057.9 EEQ29980.1 - 9.3e-38 129.7 0.0 3.8e-27 95.0 0.0 3.0 2 1 0 2 2 2 2 Putative serine esterase (DUF676) DAGK_cat PF00781.19 EEQ29980.1 - 2.8e-08 33.2 0.0 6.5e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Lipase_3 PF01764.20 EEQ29980.1 - 0.0031 17.1 0.0 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEQ29980.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ29980.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 EEQ29980.1 - 0.19 10.7 0.1 0.34 9.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Fcf1 PF04900.7 EEQ29981.1 - 3.9e-40 136.0 0.3 3.9e-40 136.0 0.2 1.7 2 0 0 2 2 2 1 Fcf1 Ras PF00071.17 EEQ29984.1 - 5.4e-65 217.7 0.1 6.5e-65 217.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ29984.1 - 5.1e-19 68.9 0.0 1.1e-18 67.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEQ29984.1 - 1.5e-13 50.3 0.1 1.9e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ29984.1 - 2.5e-07 30.0 0.0 3.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEQ29984.1 - 1.2e-06 28.0 0.1 2.1e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ29984.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ29984.1 - 0.0049 16.1 0.1 0.026 13.7 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EEQ29984.1 - 0.0054 15.9 0.1 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EEQ29984.1 - 0.089 12.9 0.0 4.5 7.4 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ29984.1 - 0.097 12.8 0.0 0.27 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEQ29984.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NCA2 PF08637.5 EEQ29985.1 - 1.7e-80 270.0 0.0 3.2e-80 269.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 RecO_N PF11967.3 EEQ29985.1 - 0.049 13.5 0.3 0.66 9.8 0.1 2.4 2 0 0 2 2 2 0 Recombination protein O N terminal FA_hydroxylase PF04116.8 EEQ29986.1 - 5.1e-16 59.0 18.9 5.1e-16 59.0 13.1 1.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily AAA PF00004.24 EEQ29987.1 - 1.1e-50 171.2 0.0 2e-34 118.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ29987.1 - 0.0005 20.1 1.5 0.043 13.7 0.2 3.2 2 1 1 3 3 3 1 AAA ATPase domain CDC48_N PF02359.13 EEQ29987.1 - 0.00057 19.7 0.0 0.0058 16.5 0.0 2.5 3 0 0 3 3 3 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 EEQ29987.1 - 0.00063 19.8 0.3 0.16 12.1 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEQ29987.1 - 0.00071 19.0 0.0 2.6 7.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain Bac_DnaA PF00308.13 EEQ29987.1 - 0.0011 18.6 0.0 0.021 14.4 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_5 PF07728.9 EEQ29987.1 - 0.0016 18.1 0.2 1.7 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EEQ29987.1 - 0.0083 15.8 0.1 0.76 9.4 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase Vps4_C PF09336.5 EEQ29987.1 - 0.012 15.5 0.0 3.3 7.6 0.1 2.9 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 EEQ29987.1 - 0.028 14.3 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.1 EEQ29987.1 - 0.047 13.2 0.6 0.095 12.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EEQ29987.1 - 0.081 12.8 0.1 14 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEQ29987.1 - 0.11 12.1 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 EEQ29987.1 - 0.12 11.2 0.0 0.36 9.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 EEQ29987.1 - 1.4 9.7 4.4 5 7.9 0.1 3.1 3 1 0 3 3 3 0 AAA domain RRM_1 PF00076.17 EEQ29988.1 - 1.4e-14 53.4 0.0 2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ29988.1 - 2.7e-11 43.2 0.0 4.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ29988.1 - 6.5e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.22 EEQ29989.1 - 3.3e-40 138.0 0.0 6.2e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EEQ29989.1 - 3.3e-37 128.2 0.0 6.1e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EEQ29989.1 - 1.6e-35 121.2 0.1 1e-34 118.7 0.0 2.6 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EEQ29989.1 - 5.8e-05 22.4 0.0 0.00014 21.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.1 EEQ29989.1 - 0.0065 16.9 0.9 8.6 7.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.17 EEQ29990.1 - 5.8e-27 93.3 0.1 7.6e-27 92.9 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EEQ29990.1 - 0.0026 17.6 0.4 0.02 14.7 0.3 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase NADH_u_ox_C PF12853.2 EEQ29991.1 - 1.7e-34 117.3 0.1 2.7e-34 116.7 0.1 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EEQ29991.1 - 8.8e-11 41.9 1.8 4.6e-10 39.6 1.2 2.2 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Swi3 PF07962.7 EEQ29992.1 - 4.2e-29 99.9 0.7 7.5e-29 99.1 0.2 1.7 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 RCC1 PF00415.13 EEQ29993.1 - 2.2e-60 200.6 17.2 6.3e-12 45.5 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEQ29993.1 - 2.9e-41 138.2 36.5 3.9e-08 32.6 0.7 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RibD_C PF01872.12 EEQ29994.1 - 5.5e-29 101.2 0.0 9e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 RibD C-terminal domain DUF2890 PF11081.3 EEQ29994.1 - 1.7 8.6 5.9 2.8 7.9 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nic96 PF04097.9 EEQ29995.1 - 6.1e-201 668.7 0.0 8.5e-201 668.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Pkinase PF00069.20 EEQ29995.1 - 1.1e-19 70.6 0.0 2.6e-19 69.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ29995.1 - 0.22 10.5 0.1 2.3 7.2 0.1 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase COX16 PF14138.1 EEQ29996.1 - 1.4e-30 105.2 0.1 2e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Y_phosphatase PF00102.22 EEQ29998.1 - 7.4e-66 221.8 0.3 1.3e-65 221.0 0.2 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EEQ29998.1 - 1.3e-09 38.3 0.0 6.9e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EEQ29998.1 - 0.0025 17.4 0.1 0.0059 16.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EEQ29998.1 - 0.04 14.1 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family TFIIA PF03153.8 EEQ29999.1 - 0.00041 20.3 21.5 0.00057 19.8 14.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit F-box-like_2 PF13013.1 EEQ29999.1 - 0.00051 19.7 0.1 0.00097 18.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain CENP-T PF15511.1 EEQ29999.1 - 0.016 14.4 11.0 0.021 14.1 7.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T F-box PF00646.28 EEQ29999.1 - 0.043 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 F-box domain CDC45 PF02724.9 EEQ29999.1 - 2 6.3 23.7 2.9 5.8 16.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EEQ29999.1 - 3.5 6.9 17.8 5.4 6.3 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FGGY_C PF02782.11 EEQ30002.1 - 5.2e-51 173.0 0.2 9.2e-51 172.2 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEQ30002.1 - 3.6e-23 82.1 0.1 9.8e-21 74.1 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain F-box-like PF12937.2 EEQ30003.1 - 0.046 13.4 0.2 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 F-box-like AAA PF00004.24 EEQ30004.1 - 1.1e-43 148.6 0.0 1.7e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ30004.1 - 4.1e-08 33.0 0.0 9.8e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ30004.1 - 8.2e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEQ30004.1 - 3.5e-06 27.1 0.1 7.8e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ30004.1 - 4.8e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ30004.1 - 6.9e-05 23.6 0.0 0.00015 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ30004.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEQ30004.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EEQ30004.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EEQ30004.1 - 0.00088 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEQ30004.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ30004.1 - 0.0017 18.2 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ30004.1 - 0.0024 16.9 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EEQ30004.1 - 0.0026 17.3 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEQ30004.1 - 0.0039 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEQ30004.1 - 0.0066 15.5 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 EEQ30004.1 - 0.0066 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEQ30004.1 - 0.0071 16.6 0.0 0.029 14.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 EEQ30004.1 - 0.018 14.5 0.0 0.085 12.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 EEQ30004.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EEQ30004.1 - 0.02 14.2 0.1 0.079 12.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 EEQ30004.1 - 0.022 14.0 0.0 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 EEQ30004.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEQ30004.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EEQ30004.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EEQ30004.1 - 0.052 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EEQ30004.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 EEQ30004.1 - 0.088 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NACHT PF05729.7 EEQ30004.1 - 0.1 12.2 0.0 0.5 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF2072 PF09845.4 EEQ30004.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Na_Ca_ex PF01699.19 EEQ30005.1 - 5.9e-31 106.9 25.8 5.9e-18 64.8 7.4 4.2 6 0 0 6 6 6 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EEQ30005.1 - 8.7e-14 51.7 10.6 8.7e-14 51.7 7.4 4.6 7 0 0 7 7 7 1 Domain of unknown function (DUF307) Peptidase_S10 PF00450.17 EEQ30006.1 - 6.2e-88 295.7 0.1 1e-87 295.0 0.1 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase DUF3674 PF12426.3 EEQ30006.1 - 0.14 11.5 0.6 0.36 10.2 0.4 1.7 1 0 0 1 1 1 0 RNA dependent RNA polymerase APH PF01636.18 EEQ30007.1 - 3.6e-14 53.0 0.0 1.7e-13 50.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ30007.1 - 0.00034 20.2 0.0 0.00063 19.3 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ30007.1 - 0.017 14.3 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.17 EEQ30007.1 - 0.045 13.0 0.1 0.61 9.3 0.0 2.5 2 2 0 2 2 2 0 RIO1 family Kdo PF06293.9 EEQ30007.1 - 0.097 11.7 0.0 4.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNase_NucA_NucB PF14040.1 EEQ30008.1 - 0.00016 21.7 0.1 0.0002 21.4 0.1 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Pro_isomerase PF00160.16 EEQ30008.1 - 0.027 14.6 0.1 0.054 13.7 0.1 1.6 1 1 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CAP_N PF01213.14 EEQ30008.1 - 0.056 12.7 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DEAD PF00270.24 EEQ30010.1 - 3.4e-17 62.4 0.0 6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EEQ30010.1 - 2.7e-07 30.6 0.4 3.8e-06 26.8 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EEQ30010.1 - 0.039 13.1 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Pkinase PF00069.20 EEQ30011.1 - 2.2e-09 36.8 0.0 4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ30011.1 - 0.0054 16.4 0.3 0.015 15.0 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EEQ30011.1 - 0.017 14.1 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase MFS_1 PF07690.11 EEQ30012.1 - 4.3e-33 114.4 40.9 1.4e-31 109.5 25.9 3.2 2 1 2 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.8 EEQ30012.1 - 2.7e-07 29.2 18.2 2.7e-07 29.2 12.6 1.7 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ30012.1 - 2.5e-06 26.3 7.4 2.5e-06 26.3 5.1 3.2 2 1 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.13 EEQ30013.1 - 3.1e-07 30.1 7.8 5.1e-07 29.4 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EEQ30014.1 - 1.5e-11 44.5 0.0 2.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ30014.1 - 3.7e-05 23.4 0.0 5.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ30014.1 - 0.0025 17.3 0.0 0.012 15.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEQ30014.1 - 0.022 14.7 0.2 0.83 9.6 0.0 2.4 2 0 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 EEQ30014.1 - 0.056 12.1 0.0 0.077 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEQ30014.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein ADH_N PF08240.7 EEQ30015.1 - 3.5e-11 42.8 0.4 1.3e-08 34.5 0.0 3.3 2 2 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ30015.1 - 4.4e-09 35.9 0.0 9.9e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding PF00501.23 EEQ30016.1 - 3.2e-76 256.3 0.0 6.4e-76 255.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EEQ30016.1 - 5.8e-76 255.3 0.1 2.4e-75 253.3 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EEQ30016.1 - 1.3e-46 159.1 0.0 2.1e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EEQ30016.1 - 2.3e-45 154.7 0.0 3.9e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 EEQ30016.1 - 2e-44 152.2 0.0 4.4e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EEQ30016.1 - 1.1e-36 126.0 0.1 1.4e-35 122.4 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein KR PF08659.5 EEQ30016.1 - 7.4e-33 113.7 4.7 7.9e-30 103.8 0.0 3.8 3 1 1 4 4 3 2 KR domain Ketoacyl-synt_C PF02801.17 EEQ30016.1 - 1.4e-28 99.0 0.0 3.5e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EEQ30016.1 - 2.5e-26 92.5 3.8 1e-22 80.8 0.1 3.8 2 1 1 3 3 3 2 short chain dehydrogenase Methyltransf_12 PF08242.7 EEQ30016.1 - 1.8e-20 73.2 0.0 4.6e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ30016.1 - 9.3e-18 64.2 0.0 2.6e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ30016.1 - 1.5e-15 57.2 0.0 6.9e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ30016.1 - 3e-13 50.0 0.0 8e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EEQ30016.1 - 4.6e-13 49.2 0.0 1.1e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 HxxPF-repeated domain PP-binding PF00550.20 EEQ30016.1 - 1.7e-12 47.3 0.2 6.7e-07 29.4 0.0 3.3 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EEQ30016.1 - 4.1e-11 43.4 0.0 4.8e-10 40.0 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ30016.1 - 1.1e-10 41.0 0.0 2.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.16 EEQ30016.1 - 1.3e-08 34.5 0.1 4.4e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.1 EEQ30016.1 - 1.2e-07 32.0 0.0 3.5e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ30016.1 - 3.1e-05 23.9 0.0 0.00028 20.8 0.0 2.7 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ30016.1 - 3.3e-05 23.3 0.0 7.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NAD_binding_10 PF13460.1 EEQ30016.1 - 3.4e-05 23.9 0.1 9.1e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEQ30016.1 - 4.4e-05 22.3 0.0 0.0033 16.1 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 EEQ30016.1 - 7e-05 21.9 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 EEQ30016.1 - 0.0033 16.4 0.0 0.0064 15.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 EEQ30016.1 - 0.017 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.12 EEQ30016.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Sec3_C_2 PF15278.1 EEQ30016.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Methyltransf_8 PF05148.10 EEQ30016.1 - 0.35 10.4 0.0 0.74 9.3 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase DHC_N2 PF08393.8 EEQ30016.1 - 2.5 6.5 0.0 11 4.3 0.0 1.8 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 APH PF01636.18 EEQ30019.1 - 3.9e-07 30.0 0.1 5.3e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Copine PF07002.11 EEQ30019.1 - 0.037 13.7 0.0 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 Copine Pkinase PF00069.20 EEQ30021.1 - 0.0026 16.9 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ30021.1 - 0.058 13.1 0.3 0.08 12.6 0.2 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C2H2 PF00096.21 EEQ30023.1 - 8.9e-09 35.1 5.7 0.00016 21.8 1.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ30023.1 - 7.6e-05 22.7 6.6 0.015 15.6 1.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ30023.1 - 1.9 8.9 5.9 26 5.3 2.0 2.7 2 0 0 2 2 2 0 Zinc-finger double domain EF1G PF00647.14 EEQ30029.1 - 0.017 14.8 0.1 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Homez PF11569.3 EEQ30029.1 - 0.096 11.7 0.1 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Ferritin PF00210.19 EEQ30029.1 - 0.11 12.2 0.4 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 Ferritin-like domain MFS_1 PF07690.11 EEQ30030.1 - 5e-42 143.8 45.4 5e-42 143.8 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ30030.1 - 0.0023 16.6 31.3 0.012 14.2 21.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TMEM169 PF15052.1 EEQ30030.1 - 0.093 12.6 2.6 0.12 12.2 0.8 2.0 2 0 0 2 2 2 0 TMEM169 protein family Radical_SAM PF04055.16 EEQ30031.1 - 2.1e-23 83.3 0.1 4.6e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EEQ30031.1 - 4.2e-22 78.0 0.0 1.2e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EEQ30031.1 - 1e-09 38.5 0.1 4.9e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 Flavodoxin Ald_Xan_dh_C PF01315.17 EEQ30031.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Pro_dh PF01619.13 EEQ30032.1 - 5.3e-41 140.6 0.8 6.9e-41 140.2 0.5 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Aldedh PF00171.17 EEQ30033.1 - 7.6e-103 344.3 0.1 9.3e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OCD_Mu_crystall PF02423.10 EEQ30034.1 - 4.5e-12 45.3 0.0 2.6e-07 29.7 0.0 3.2 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EEQ30034.1 - 0.0018 18.3 0.0 0.0074 16.3 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.13 EEQ30035.1 - 1.7e-05 24.6 10.0 2.5e-05 24.0 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ30035.1 - 0.1 11.4 1.5 3.5 6.4 0.1 2.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain USP8_interact PF08941.5 EEQ30035.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 USP8 interacting Amino_oxidase PF01593.19 EEQ30036.1 - 1.5e-42 146.2 0.1 1.7e-27 96.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEQ30036.1 - 2.6e-08 33.7 0.0 9e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEQ30036.1 - 4.4e-06 26.9 0.0 2.6e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ30036.1 - 1.1e-05 24.4 0.2 3.6e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEQ30036.1 - 8e-05 22.7 0.0 0.00053 20.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ30036.1 - 0.00039 20.3 0.1 0.03 14.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ30036.1 - 0.00068 18.5 0.0 0.00091 18.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EEQ30036.1 - 0.0082 15.2 1.5 0.013 14.5 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EEQ30036.1 - 0.0097 14.4 0.1 0.014 13.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EEQ30036.1 - 0.034 13.0 0.1 0.048 12.5 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EEQ30036.1 - 0.052 13.1 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EEQ30036.1 - 0.074 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EEQ30036.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zip PF02535.17 EEQ30037.1 - 0.73 8.7 3.3 1.2 8.1 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Metallophos_2 PF12850.2 EEQ30038.1 - 3.7e-07 30.1 0.1 1.3e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEQ30038.1 - 0.2 11.0 1.0 2.1 7.7 0.7 2.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase DUF2183 PF09949.4 EEQ30039.1 - 1.4e-32 111.5 0.0 4.5e-32 109.9 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 EEQ30039.1 - 0.024 14.6 0.1 0.26 11.3 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain DnaJ-X PF14308.1 EEQ30039.1 - 0.35 10.1 4.2 0.59 9.3 2.9 1.3 1 0 0 1 1 1 0 X-domain of DnaJ-containing DUF2232 PF09991.4 EEQ30039.1 - 2.8 6.8 6.0 4 6.3 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) APH PF01636.18 EEQ30040.1 - 0.017 14.8 0.2 0.041 13.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family PI31_Prot_C PF08577.6 EEQ30041.1 - 4.7e-19 68.7 12.8 4.7e-19 68.7 8.9 3.9 4 0 0 4 4 4 1 PI31 proteasome regulator PI31_Prot_N PF11566.3 EEQ30041.1 - 3.2e-14 52.7 0.0 7.5e-13 48.3 0.0 2.0 1 1 1 2 2 2 2 PI31 proteasome regulator N-terminal Metallophos PF00149.23 EEQ30042.1 - 2.9e-44 150.8 0.8 3.7e-44 150.5 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.1 EEQ30043.1 - 2.3e-17 63.5 0.0 2.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ30043.1 - 6e-10 39.2 0.3 1.3e-09 38.1 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase DUF3112 PF11309.3 EEQ30044.1 - 4.1e-48 163.1 15.3 1.2e-45 155.2 2.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) TPR_11 PF13414.1 EEQ30045.1 - 9.2e-14 50.8 2.3 6.8e-13 48.0 0.5 2.2 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EEQ30045.1 - 9.8e-08 31.2 0.2 0.01 15.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ30045.1 - 9.2e-07 28.3 0.6 0.065 13.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ30045.1 - 0.0001 22.1 1.7 0.00014 21.6 0.4 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ30045.1 - 0.00076 19.0 0.3 0.72 9.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ30045.1 - 0.0037 17.3 1.0 0.0087 16.1 0.4 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEQ30045.1 - 0.075 12.8 0.5 3.5 7.5 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EEQ30046.1 - 1.8e-28 99.3 0.0 4.1e-28 98.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30046.1 - 3.2e-12 46.0 0.0 1.1e-10 41.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Scramblase PF03803.10 EEQ30046.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Scramblase Pox_ser-thr_kin PF05445.6 EEQ30046.1 - 0.12 11.1 0.6 0.17 10.6 0.4 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HAD_2 PF13419.1 EEQ30047.1 - 1.2e-14 54.9 0.0 1.6e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ30047.1 - 4.3e-05 23.1 0.0 0.00021 20.9 0.0 2.2 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 EEQ30047.1 - 8.6e-05 23.0 0.0 0.00032 21.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PAXIP1_C PF15364.1 EEQ30048.1 - 0.026 14.4 0.6 0.055 13.3 0.4 1.5 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein WD40 PF00400.27 EEQ30050.1 - 5.4e-09 35.5 10.5 0.19 11.6 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Lactonase PF10282.4 EEQ30050.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Nucleoporin_FG PF13634.1 EEQ30051.1 - 9.9e-09 35.4 88.5 0.0016 18.6 14.2 3.4 1 1 2 3 3 3 3 Nucleoporin FG repeat region Cpn10 PF00166.16 EEQ30053.1 - 2.3e-20 72.3 0.0 2.9e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Fip1 PF05182.8 EEQ30054.1 - 5.6e-22 76.7 1.6 9.9e-22 75.9 1.1 1.4 1 0 0 1 1 1 1 Fip1 motif XAP5 PF04921.9 EEQ30055.1 - 7.5e-79 264.6 0.0 4.8e-78 262.0 0.0 1.8 2 0 0 2 2 2 1 XAP5, circadian clock regulator Menin PF05053.8 EEQ30055.1 - 1.2 7.1 3.7 1.8 6.6 2.5 1.2 1 0 0 1 1 1 0 Menin zf-RING_5 PF14634.1 EEQ30056.1 - 1.3e-08 34.4 7.9 3.2e-08 33.1 5.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ30056.1 - 4.6e-05 23.3 5.5 0.00013 21.8 3.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ30056.1 - 0.00015 21.4 8.6 0.00038 20.2 5.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ30056.1 - 0.0023 17.5 9.5 0.0061 16.1 6.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEQ30056.1 - 0.011 15.6 5.5 0.011 15.6 3.8 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF2130 PF09903.4 EEQ30056.1 - 0.018 13.7 1.8 0.026 13.2 1.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Prefoldin PF02996.12 EEQ30056.1 - 0.029 14.0 1.4 0.071 12.7 0.6 1.9 1 1 1 2 2 2 0 Prefoldin subunit zf-RING_6 PF14835.1 EEQ30056.1 - 0.033 13.9 4.7 0.074 12.8 3.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1664 PF07889.7 EEQ30056.1 - 0.048 13.4 1.8 0.086 12.6 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Lge1 PF11488.3 EEQ30056.1 - 0.061 13.5 0.7 0.13 12.4 0.5 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF1732 PF08340.6 EEQ30056.1 - 0.083 12.7 0.7 0.22 11.3 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) Sec23_helical PF04815.10 EEQ30056.1 - 0.087 12.2 0.6 1.1 8.7 0.3 2.6 1 1 0 1 1 1 0 Sec23/Sec24 helical domain AhpC-TSA PF00578.16 EEQ30056.1 - 0.33 10.6 0.0 0.33 10.6 0.0 2.5 3 0 0 3 3 3 0 AhpC/TSA family zf-rbx1 PF12678.2 EEQ30056.1 - 0.36 10.9 5.4 1.1 9.4 3.8 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EEQ30056.1 - 0.43 10.2 4.5 1.1 8.8 3.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF904 PF06005.7 EEQ30056.1 - 0.66 10.3 4.3 0.98 9.7 2.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) zf-P11 PF03854.9 EEQ30056.1 - 3 7.4 8.1 3.6 7.1 4.0 2.4 1 1 1 2 2 2 0 P-11 zinc finger zf-MIZ PF02891.15 EEQ30056.1 - 3.7 7.1 7.7 8.5 5.9 5.3 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_3 PF13920.1 EEQ30057.1 - 4.6e-09 35.7 12.4 7.7e-09 35.0 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Asp PF00026.18 EEQ30058.1 - 1.9e-18 66.7 0.3 2.8e-18 66.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease ThiF PF00899.16 EEQ30060.1 - 1.8e-09 37.5 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 ThiF family Rib_5-P_isom_A PF06026.9 EEQ30061.1 - 1.9e-36 125.0 0.0 7.9e-35 119.7 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) WD40 PF00400.27 EEQ30062.1 - 1.1e-18 66.2 2.6 0.005 16.6 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat FHA PF00498.21 EEQ30062.1 - 0.15 12.1 0.2 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 FHA domain ATP_bind_1 PF03029.12 EEQ30063.1 - 2.7e-76 256.2 0.0 3.3e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EEQ30063.1 - 0.00037 20.0 0.0 0.00056 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 EEQ30063.1 - 0.00043 21.1 1.8 0.0015 19.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EEQ30063.1 - 0.0011 17.8 0.2 0.0023 16.7 0.0 1.5 2 0 0 2 2 2 1 ArgK protein CbiA PF01656.18 EEQ30063.1 - 0.0029 17.0 0.0 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 EEQ30063.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EEQ30063.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.5 EEQ30063.1 - 0.022 13.9 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EEQ30063.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEQ30063.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Polysacc_deac_2 PF04748.8 EEQ30063.1 - 0.052 12.5 0.1 0.098 11.6 0.1 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase RNA_helicase PF00910.17 EEQ30063.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EEQ30063.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Fer4_NifH PF00142.13 EEQ30063.1 - 0.089 11.9 0.2 0.21 10.7 0.0 1.6 1 1 1 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Zeta_toxin PF06414.7 EEQ30063.1 - 0.1 11.7 0.0 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 EEQ30063.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNase_P_Rpp14 PF01900.14 EEQ30064.1 - 1.1e-35 121.8 0.0 1.3e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family CoA_binding PF02629.14 EEQ30065.1 - 5.3e-18 65.3 0.1 2e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Citrate_synt PF00285.16 EEQ30065.1 - 5.8e-18 64.7 0.0 2e-15 56.4 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EEQ30065.1 - 2.5e-13 49.8 0.1 4.3e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EEQ30065.1 - 7.9e-05 22.2 0.0 0.00083 18.9 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EEQ30066.1 - 1.1e-07 31.4 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ank_2 PF12796.2 EEQ30067.1 - 3.6e-11 43.2 0.6 2.5e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ30067.1 - 2.7e-06 27.4 5.6 0.0028 17.8 0.6 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EEQ30067.1 - 9.4e-05 22.0 3.3 0.41 10.5 0.0 4.7 4 1 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 EEQ30067.1 - 0.00059 19.8 6.6 7.3 7.1 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EEQ30067.1 - 0.0019 18.6 1.7 1.1 9.8 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) CFEM PF05730.6 EEQ30068.1 - 1e-16 60.5 9.1 1.5e-16 59.9 6.3 1.3 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.6 EEQ30068.1 - 0.29 10.8 14.8 0.41 10.3 10.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DNA_pol_delta_4 PF04081.8 EEQ30069.1 - 1.8e-27 96.0 0.5 2.7e-27 95.5 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Amidase PF01425.16 EEQ30070.1 - 8.7e-90 301.6 0.0 1e-89 301.4 0.0 1.1 1 0 0 1 1 1 1 Amidase APH PF01636.18 EEQ30072.1 - 8.3e-19 68.2 0.0 2.2e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEQ30072.1 - 0.0086 15.0 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase Pkinase_Tyr PF07714.12 EEQ30072.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.15 EEQ30072.1 - 0.021 14.3 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ30072.1 - 0.031 13.6 0.1 0.21 10.9 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EEQ30072.1 - 0.033 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF1679 PF07914.6 EEQ30072.1 - 0.052 12.1 0.0 2.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) UBN2_2 PF14227.1 EEQ30072.1 - 0.11 12.0 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type ORC6 PF05460.8 EEQ30073.1 - 3.6e-48 164.4 2.0 5.3e-48 163.9 1.4 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF1016 PF06250.6 EEQ30073.1 - 0.065 12.1 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) DUF2419 PF10343.4 EEQ30074.1 - 3.4e-136 453.1 0.0 4e-136 452.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ThiF PF00899.16 EEQ30075.1 - 3.2e-42 143.5 0.0 6.5e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EEQ30075.1 - 3.9e-28 96.8 1.0 7.4e-28 95.9 0.7 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EEQ30075.1 - 3.8e-22 78.1 0.2 8.1e-22 77.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EEQ30075.1 - 8.4e-22 76.2 2.4 8.4e-22 76.2 1.7 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EEQ30075.1 - 9.1e-05 22.6 0.0 0.00038 20.6 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EEQ30075.1 - 0.022 14.8 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EEQ30075.1 - 0.067 13.6 0.1 3.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EEQ30076.1 - 1.5e-23 83.5 2.7 1.7e-22 80.0 1.8 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ30076.1 - 1.3e-11 44.6 0.0 2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ30076.1 - 5.8e-08 32.6 2.9 7.7e-07 28.9 2.0 2.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ30076.1 - 5.4e-06 26.0 0.1 1.3e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EEQ30076.1 - 0.011 15.8 0.2 0.14 12.2 0.1 2.5 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 EEQ30076.1 - 0.012 14.5 0.1 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.10 EEQ30076.1 - 0.027 13.3 0.0 0.049 12.5 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Skp1_POZ PF03931.10 EEQ30077.1 - 4e-10 39.6 0.0 5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain tRNA_int_end_N2 PF12928.2 EEQ30078.1 - 4.1e-34 115.8 0.0 6.2e-34 115.2 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EEQ30078.1 - 0.0043 16.5 0.0 0.0083 15.6 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.17 EEQ30079.1 - 1.1e-15 57.9 0.0 3.9e-15 56.1 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 EEQ30080.1 - 3.5e-35 121.5 0.0 4.3e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-ZPR1 PF03367.8 EEQ30081.1 - 1.6e-99 329.7 0.1 1.4e-49 167.3 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain SF-assemblin PF06705.6 EEQ30081.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 SF-assemblin/beta giardin HypA PF01155.14 EEQ30081.1 - 0.2 11.3 1.8 5.1 6.8 0.0 2.6 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family DUF824 PF05688.6 EEQ30081.1 - 0.27 10.8 0.8 0.81 9.3 0.0 2.2 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) zf-ISL3 PF14690.1 EEQ30081.1 - 1.8 8.6 7.7 46 4.1 0.0 3.5 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rpr2 PF04032.11 EEQ30082.1 - 8.6e-08 31.9 0.2 1.9e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.5 EEQ30082.1 - 0.057 13.3 2.0 3.9 7.5 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DBR1 PF05011.8 EEQ30083.1 - 1.4e-45 154.7 0.0 3.8e-45 153.3 0.0 1.8 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EEQ30083.1 - 0.00011 21.6 1.8 0.00022 20.7 1.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2435 PF10363.4 EEQ30084.1 - 2.3e-25 88.3 0.1 8e-25 86.5 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EEQ30084.1 - 2e-07 30.3 0.0 4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DUF948 PF06103.6 EEQ30084.1 - 0.11 12.4 0.4 1.3 8.9 0.3 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Polysacc_deac_1 PF01522.16 EEQ30086.1 - 6.4e-27 93.6 0.0 1.4e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EEQ30086.1 - 1.4e-06 28.1 39.9 2.8e-05 24.0 9.4 2.5 2 0 0 2 2 2 2 Chitin recognition protein CBM_19 PF03427.8 EEQ30088.1 - 6.7 6.5 8.5 2.9 7.7 4.1 2.0 1 1 0 1 1 1 0 Carbohydrate binding domain (family 19) FAD_binding_3 PF01494.14 EEQ30089.1 - 3.6e-15 55.8 0.1 2.2e-14 53.3 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEQ30089.1 - 7.8e-09 34.9 0.7 9.4e-05 21.4 0.5 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEQ30089.1 - 1.5e-05 25.2 0.1 0.0025 18.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ30089.1 - 0.0042 15.9 0.5 0.0066 15.3 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EEQ30089.1 - 0.011 15.7 0.2 0.033 14.2 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ30089.1 - 0.03 14.2 0.1 0.13 12.0 0.1 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Clathrin PF00637.15 EEQ30090.1 - 4.3e-18 65.3 0.3 1.9e-15 56.7 0.7 3.1 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 EEQ30090.1 - 1.1e-17 63.6 0.1 2.5e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 EEQ30090.1 - 0.00072 19.2 6.9 0.0015 18.2 4.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEQ30090.1 - 0.0018 18.0 6.9 0.0035 17.1 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ30090.1 - 0.0036 17.3 6.6 0.0068 16.4 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EEQ30090.1 - 0.014 14.9 0.0 0.053 13.1 0.0 2.0 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.1 EEQ30090.1 - 0.019 15.5 0.1 2.6 8.8 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.2 EEQ30090.1 - 0.026 14.6 2.8 0.05 13.7 2.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEQ30090.1 - 0.026 14.1 6.4 0.049 13.2 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 EEQ30090.1 - 0.05 13.5 5.3 0.66 9.9 0.1 3.6 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ30090.1 - 0.053 13.3 1.2 0.31 10.9 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-RING_6 PF14835.1 EEQ30090.1 - 0.12 12.1 1.4 0.26 11.0 1.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EEQ30090.1 - 0.13 12.1 2.7 0.32 10.8 1.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_2 PF07719.12 EEQ30090.1 - 0.6 10.1 3.3 0.48 10.4 0.1 2.6 3 0 0 3 3 1 0 Tetratricopeptide repeat PHD PF00628.24 EEQ30090.1 - 2.7 7.7 5.9 5.7 6.7 4.1 1.6 1 0 0 1 1 1 0 PHD-finger adh_short_C2 PF13561.1 EEQ30091.1 - 6.4e-29 101.4 0.0 7.2e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ30091.1 - 4.1e-28 98.3 0.1 5.2e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ30091.1 - 7.7e-15 55.0 0.0 1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Mrr_cat PF04471.7 EEQ30091.1 - 0.044 13.5 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Restriction endonuclease YjeF_N PF03853.10 EEQ30091.1 - 0.071 12.7 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus LRR_4 PF12799.2 EEQ30093.1 - 1.4e-24 85.2 36.2 4.3e-08 32.5 0.4 9.0 5 2 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ30093.1 - 1.6e-17 62.9 40.6 9.2e-06 25.3 3.5 6.9 5 2 2 8 8 8 5 Leucine rich repeat LRR_1 PF00560.28 EEQ30093.1 - 6.3e-12 43.7 32.9 0.39 10.9 0.3 12.6 11 2 1 12 12 12 5 Leucine Rich Repeat LRR_6 PF13516.1 EEQ30093.1 - 2.4e-05 23.9 32.7 1.1 9.5 0.6 9.6 8 2 1 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 EEQ30093.1 - 0.0017 18.1 43.4 3 8.4 0.2 11.9 12 0 0 12 12 12 2 Leucine rich repeat LRR_9 PF14580.1 EEQ30093.1 - 0.0061 16.1 4.5 8.8 5.8 0.3 3.8 2 1 2 4 4 4 3 Leucine-rich repeat IPK PF03770.11 EEQ30094.1 - 2.3e-57 193.8 0.0 3.7e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 EEQ30094.1 - 0.033 13.8 0.1 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.11 EEQ30096.1 - 1.2e-11 43.9 8.4 1.7e-11 43.4 5.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EEQ30096.1 - 0.016 14.4 1.3 0.016 14.4 0.9 2.6 3 0 0 3 3 3 0 Nodulin-like ERCC4 PF02732.10 EEQ30097.1 - 1.4e-17 63.7 0.0 3e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain DUF3043 PF11241.3 EEQ30097.1 - 0.11 12.0 5.7 0.27 10.7 4.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DDHD PF02862.12 EEQ30097.1 - 1.5 8.5 8.0 16 5.2 5.8 2.3 2 0 0 2 2 2 0 DDHD domain WD40 PF00400.27 EEQ30098.1 - 1.7e-63 208.3 12.8 9.6e-10 37.9 0.0 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EEQ30098.1 - 7.2e-12 44.8 1.2 1.9e-11 43.4 0.8 1.8 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EEQ30098.1 - 3e-10 38.8 9.7 0.00029 19.1 0.2 5.5 3 1 2 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 EEQ30098.1 - 1e-09 37.7 1.7 1.2e-09 37.5 0.1 2.1 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 EEQ30098.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Elongin_A PF06881.6 EEQ30098.1 - 0.06 13.7 0.1 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Peptidase_M19 PF01244.16 EEQ30099.1 - 1.2e-108 362.9 0.0 1.4e-108 362.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Glycos_transf_1 PF00534.15 EEQ30100.1 - 2.3e-29 101.9 0.0 3.6e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEQ30100.1 - 7.7e-10 38.7 0.0 0.0003 20.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EEQ30100.1 - 1.8e-07 31.3 0.0 4.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEQ30100.1 - 3.7e-07 30.4 0.1 6.7e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EEQ30100.1 - 4.1e-05 23.7 0.0 8.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2184 PF09950.4 EEQ30100.1 - 0.076 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) Kinesin PF00225.18 EEQ30101.1 - 4.4e-92 308.3 0.1 3.6e-91 305.3 0.0 2.7 2 0 0 2 2 2 1 Kinesin motor domain DUF1980 PF09323.5 EEQ30101.1 - 1.1 8.9 4.7 9.1 5.9 3.3 2.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Sad1_UNC PF07738.8 EEQ30102.1 - 3.2e-14 52.8 0.0 8.2e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal WD40 PF00400.27 EEQ30103.1 - 2.4e-35 119.1 8.3 3.3e-10 39.4 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EEQ30103.1 - 1.7e-07 29.7 9.5 0.052 11.6 0.1 5.7 4 2 2 6 6 6 4 Nucleoporin Nup120/160 Seryl_tRNA_N PF02403.17 EEQ30103.1 - 0.0076 16.2 0.3 0.017 15.1 0.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain BBS2_Mid PF14783.1 EEQ30103.1 - 0.019 14.7 0.3 0.55 10.0 0.0 3.4 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF1664 PF07889.7 EEQ30103.1 - 0.021 14.5 1.2 0.19 11.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PQQ_2 PF13360.1 EEQ30103.1 - 0.037 13.5 0.1 0.26 10.7 0.0 2.2 1 1 0 2 2 2 0 PQQ-like domain Leu_zip PF15294.1 EEQ30103.1 - 0.099 11.7 0.4 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Leucine zipper ADH_zinc_N PF00107.21 EEQ30103.1 - 0.11 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase V_ATPase_I PF01496.14 EEQ30103.1 - 0.24 9.2 0.0 0.33 8.7 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CM_2 PF01817.16 EEQ30104.1 - 1.7e-08 34.3 0.4 3.1e-06 27.1 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II BCIP PF13862.1 EEQ30105.1 - 2.4e-72 242.5 0.1 2.9e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein GMP_synt_C PF00958.17 EEQ30106.1 - 2.4e-38 129.7 0.0 4.8e-38 128.7 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EEQ30106.1 - 2.5e-38 131.4 0.0 4.2e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EEQ30106.1 - 3e-10 39.4 0.1 6.1e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EEQ30106.1 - 1.8e-08 34.1 0.0 3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EEQ30106.1 - 0.0028 16.9 0.0 0.015 14.5 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EEQ30106.1 - 0.0045 15.5 0.0 0.0099 14.4 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 EEQ30106.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EEQ30106.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Arginosuc_synth PF00764.14 EEQ30106.1 - 0.017 14.2 0.1 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.14 EEQ30106.1 - 0.045 13.5 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 EEQ30106.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 PP-loop family AMP-binding PF00501.23 EEQ30108.1 - 0 1395.2 0.0 3.5e-89 299.0 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 EEQ30108.1 - 0 1298.0 0.0 2.7e-53 180.7 0.0 10.7 10 0 0 10 10 10 10 Condensation domain PP-binding PF00550.20 EEQ30108.1 - 2.1e-75 248.9 5.0 6e-11 42.4 0.2 8.1 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ30108.1 - 1.1e-25 90.3 1.5 4.2e-06 27.6 0.0 5.8 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EEQ30108.1 - 2.3e-09 36.2 0.2 0.033 12.6 0.0 5.6 6 0 0 6 6 6 3 Transferase family HxxPF_rpt PF13745.1 EEQ30108.1 - 0.0023 18.1 0.0 3.5 7.9 0.0 4.2 4 0 0 4 4 4 1 HxxPF-repeated domain UPF0128 PF03673.8 EEQ30108.1 - 1.3 8.2 0.0 9.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) ABC_tran PF00005.22 EEQ30109.1 - 1.1e-47 161.7 0.4 1.8e-26 93.0 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ30109.1 - 3.8e-31 108.5 41.1 4.1e-26 92.0 11.9 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEQ30109.1 - 1.1e-12 48.5 3.6 0.0021 18.0 0.0 4.4 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 EEQ30109.1 - 1.5e-09 37.4 4.6 0.0024 17.1 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EEQ30109.1 - 3.7e-07 29.8 0.1 0.0049 16.3 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_29 PF13555.1 EEQ30109.1 - 8e-07 28.5 0.6 0.005 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EEQ30109.1 - 4.8e-06 25.8 0.2 0.0012 18.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ30109.1 - 1e-05 25.6 0.2 0.038 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EEQ30109.1 - 2e-05 25.0 1.5 0.0042 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEQ30109.1 - 2.5e-05 23.7 0.6 0.046 13.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ30109.1 - 4.7e-05 23.3 0.1 0.077 12.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EEQ30109.1 - 0.00031 20.5 0.0 0.031 13.9 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase Miro PF08477.8 EEQ30109.1 - 0.00043 20.7 0.5 0.98 9.9 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 EEQ30109.1 - 0.00045 20.4 1.0 0.07 13.3 0.0 3.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EEQ30109.1 - 0.0013 18.3 0.2 0.16 11.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EEQ30109.1 - 0.0016 18.6 3.5 0.45 10.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EEQ30109.1 - 0.0019 17.1 0.3 0.055 12.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein ArgK PF03308.11 EEQ30109.1 - 0.0046 15.7 1.6 1.6 7.4 0.2 2.4 2 0 0 2 2 2 2 ArgK protein Zeta_toxin PF06414.7 EEQ30109.1 - 0.006 15.7 0.4 0.85 8.6 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EEQ30109.1 - 0.009 16.1 0.4 1.3 9.2 0.1 3.1 2 1 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 EEQ30109.1 - 0.01 15.3 0.2 0.66 9.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EEQ30109.1 - 0.011 15.4 1.7 3.7 7.2 0.3 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EEQ30109.1 - 0.011 16.5 2.0 0.61 10.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EEQ30109.1 - 0.011 15.5 0.3 0.22 11.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 EEQ30109.1 - 0.012 15.1 0.1 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EEQ30109.1 - 0.016 15.0 1.6 0.22 11.3 0.1 2.5 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.17 EEQ30109.1 - 0.016 14.0 3.7 0.066 12.0 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Adeno_IVa2 PF02456.10 EEQ30109.1 - 0.019 13.6 0.1 0.096 11.3 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.1 EEQ30109.1 - 0.019 15.2 0.3 1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EEQ30109.1 - 0.025 13.4 0.1 1.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.7 EEQ30109.1 - 0.027 14.1 4.0 0.07 12.7 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.1 EEQ30109.1 - 0.039 13.5 0.7 7.2 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EEQ30109.1 - 0.042 13.7 0.1 2.5 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEQ30109.1 - 0.044 13.5 0.6 0.43 10.3 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 EEQ30109.1 - 0.15 11.4 5.9 0.36 10.2 0.4 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EEQ30109.1 - 0.16 11.6 2.8 9.5 5.8 0.1 2.5 2 0 0 2 2 2 0 NTPase ABC_ATPase PF09818.4 EEQ30109.1 - 0.2 10.1 2.4 3.2 6.2 0.1 3.1 4 0 0 4 4 4 0 Predicted ATPase of the ABC class DUF87 PF01935.12 EEQ30109.1 - 0.8 9.4 5.4 0.39 10.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Fungal_trans_2 PF11951.3 EEQ30110.1 - 1.5e-42 145.5 0.0 4.1e-40 137.5 0.0 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain SelP_N PF04592.9 EEQ30111.1 - 0.31 10.3 9.7 0.45 9.8 6.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EEQ30111.1 - 0.56 9.1 4.9 0.75 8.7 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-C4H2 PF10146.4 EEQ30111.1 - 6.9 6.6 7.6 13 5.6 5.3 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein MFS_1 PF07690.11 EEQ30112.1 - 4.5e-33 114.4 21.4 4.5e-33 114.4 14.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 EEQ30113.1 - 5e-10 39.5 0.3 3.9e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ30113.1 - 0.00027 20.8 0.0 0.072 12.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ30113.1 - 0.00043 20.0 0.0 0.0027 17.3 0.0 1.9 2 0 0 2 2 2 1 KR domain Permease PF02405.11 EEQ30113.1 - 0.015 14.8 0.1 0.043 13.2 0.0 1.7 2 0 0 2 2 2 0 Permease DUF460 PF04312.8 EEQ30113.1 - 0.03 13.8 0.1 0.053 13.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF460) Amino_oxidase PF01593.19 EEQ30114.1 - 1.5e-66 225.3 0.2 2.6e-66 224.5 0.1 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEQ30114.1 - 2.2e-09 37.2 0.1 5.3e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEQ30114.1 - 0.0004 20.4 0.3 0.0018 18.3 0.1 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ30114.1 - 0.0015 18.8 0.4 0.082 13.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ30114.1 - 0.003 16.5 0.4 0.073 11.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ30114.1 - 0.01 15.7 0.0 0.029 14.2 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ30114.1 - 0.016 14.2 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EEQ30114.1 - 0.016 14.9 1.8 4.7 6.9 0.2 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EEQ30114.1 - 0.06 13.4 0.1 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EEQ30114.1 - 0.11 11.5 0.0 0.25 10.3 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 EEQ30114.1 - 0.13 12.2 0.6 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Rick_17kDa_Anti PF05433.10 EEQ30115.1 - 9.4 5.9 6.7 3.9 7.2 1.1 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain RRM_1 PF00076.17 EEQ30122.1 - 1.5e-08 34.1 0.0 5.7e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EEQ30122.1 - 3.7e-06 27.2 1.1 8.2e-06 26.1 0.8 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_6 PF14259.1 EEQ30122.1 - 4.8e-06 26.4 0.0 8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ30122.1 - 0.00077 19.2 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IER PF05760.7 EEQ30122.1 - 0.018 14.9 0.5 0.021 14.7 0.4 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF3628 PF12300.3 EEQ30122.1 - 0.045 13.8 8.4 0.066 13.2 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) HSP33 PF01430.14 EEQ30122.1 - 0.05 12.7 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein HTH_32 PF13565.1 EEQ30122.1 - 0.14 12.9 1.0 0.26 12.1 0.1 1.8 2 1 0 2 2 2 0 Homeodomain-like domain HeLo PF14479.1 EEQ30124.1 - 2.3e-09 37.3 0.0 2e-07 30.9 0.0 2.1 1 1 1 2 2 2 2 Prion-inhibition and propagation Glyco_hydro_72 PF03198.9 EEQ30125.1 - 1.5e-117 392.1 0.1 2.1e-117 391.6 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EEQ30125.1 - 6.4e-05 22.3 0.0 0.016 14.3 0.0 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MAS20 PF02064.10 EEQ30126.1 - 2.7e-18 66.0 0.2 4.9e-18 65.1 0.1 1.4 1 1 0 1 1 1 1 MAS20 protein import receptor Vps51 PF08700.6 EEQ30127.1 - 4.4e-16 58.4 2.1 4.4e-16 58.4 1.4 2.2 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EEQ30127.1 - 3.1e-05 23.8 2.0 9e-05 22.3 0.1 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2443 PF10398.4 EEQ30127.1 - 0.34 10.7 1.6 40 4.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2443) IncA PF04156.9 EEQ30127.1 - 0.44 10.1 3.4 0.6 9.6 0.1 2.4 2 0 0 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 EEQ30127.1 - 4.4 7.1 6.7 0.67 9.7 0.8 2.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.22 EEQ30128.1 - 2.1e-20 73.4 0.0 8.9e-09 35.7 0.0 3.3 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EEQ30128.1 - 1.1e-08 35.4 1.4 0.00029 20.9 0.1 3.2 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EEQ30128.1 - 0.00012 21.9 0.0 0.039 13.8 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EEQ30128.1 - 0.25 10.1 0.1 17 4.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF3584 PF12128.3 EEQ30128.1 - 0.25 8.6 0.0 0.36 8.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_23 PF13476.1 EEQ30128.1 - 0.29 11.4 0.8 0.56 10.5 0.6 1.4 1 0 0 1 1 1 0 AAA domain CPSase_L_D2 PF02786.12 EEQ30129.1 - 5.8e-115 381.8 0.3 1.8e-83 279.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EEQ30129.1 - 1.3e-47 160.6 0.0 2.6e-47 159.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EEQ30129.1 - 7.5e-45 152.7 0.0 3.6e-44 150.5 0.0 2.2 3 0 0 3 3 3 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EEQ30129.1 - 9.8e-42 141.9 0.0 1.9e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EEQ30129.1 - 9.4e-41 138.4 0.1 3.1e-40 136.7 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EEQ30129.1 - 1.9e-40 137.3 0.0 1.9e-19 69.7 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EEQ30129.1 - 2.2e-37 128.6 0.2 2.6e-22 79.4 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 EEQ30129.1 - 2.1e-35 121.9 0.0 5.6e-35 120.5 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 EEQ30129.1 - 4.7e-23 80.9 0.0 3.9e-22 77.9 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.1 EEQ30129.1 - 2.2e-22 79.2 0.1 2.7e-10 39.4 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEQ30129.1 - 1.9e-16 60.1 0.4 3.8e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EEQ30129.1 - 3.1e-16 59.2 0.1 2.6e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EEQ30129.1 - 2.2e-06 27.6 0.4 0.02 14.7 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EEQ30129.1 - 5.3e-06 26.0 0.1 0.00013 21.5 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.14 EEQ30129.1 - 0.00074 19.1 0.1 1 8.8 0.0 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 EEQ30129.1 - 0.098 12.1 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family TrkA_N PF02254.13 EEQ30129.1 - 0.12 12.3 0.1 1.8 8.5 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain NfeD PF01957.13 EEQ30130.1 - 0.3 11.2 2.7 0.35 10.9 0.1 2.3 1 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding Ion_trans PF00520.26 EEQ30131.1 - 5.5e-06 25.7 24.2 2.3e-05 23.7 16.7 1.9 1 1 0 1 1 1 1 Ion transport protein Synaptobrevin PF00957.16 EEQ30132.1 - 1.2e-31 108.1 0.0 1.5e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EEQ30132.1 - 1.2e-25 88.8 0.0 2e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2628 PF10947.3 EEQ30132.1 - 0.15 11.8 1.5 0.29 10.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) KOW PF00467.24 EEQ30133.1 - 2.1e-08 33.5 2.1 2.1e-08 33.5 1.5 1.9 3 0 0 3 3 3 1 KOW motif zf-CCCH PF00642.19 EEQ30135.1 - 0.00012 21.7 1.2 0.00012 21.7 0.8 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CS PF04969.11 EEQ30136.1 - 0.042 14.3 0.6 0.075 13.5 0.1 1.7 2 0 0 2 2 2 0 CS domain Snf7 PF03357.16 EEQ30137.1 - 4.8e-20 71.6 14.2 5.9e-20 71.3 8.0 1.9 1 1 1 2 2 2 1 Snf7 DUF826 PF05696.6 EEQ30137.1 - 0.016 15.3 0.7 0.04 14.0 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF826) DUF1704 PF08014.6 EEQ30137.1 - 0.037 13.0 1.2 0.053 12.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) BMFP PF04380.8 EEQ30137.1 - 1.6 8.9 9.4 1.1 9.4 0.2 4.1 3 1 2 5 5 5 0 Membrane fusogenic activity MerR-DNA-bind PF09278.6 EEQ30137.1 - 4.3 7.8 15.6 5.9 7.3 1.2 3.9 4 0 0 4 4 4 0 MerR, DNA binding F-box-like PF12937.2 EEQ30138.1 - 5.7e-09 35.5 0.1 1.3e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ30138.1 - 4e-08 32.7 0.2 8.1e-08 31.7 0.2 1.5 1 0 0 1 1 1 1 F-box domain Mre11_DNA_bind PF04152.9 EEQ30139.1 - 1.2e-56 191.3 0.1 2.3e-56 190.3 0.1 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EEQ30139.1 - 1e-24 87.0 2.1 1.5e-24 86.5 1.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EEQ30139.1 - 0.027 13.6 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily FAM220 PF15487.1 EEQ30139.1 - 0.85 8.9 5.2 2 7.6 3.6 1.6 1 0 0 1 1 1 0 FAM220 family DUF1446 PF07287.6 EEQ30140.1 - 1.2e-122 408.8 0.1 1.5e-122 408.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) GST_C PF00043.20 EEQ30141.1 - 6.3e-17 61.3 0.0 1.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEQ30141.1 - 2.3e-11 43.7 0.0 4.5e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEQ30141.1 - 2.8e-11 43.4 0.0 5.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ30141.1 - 1.3e-10 40.9 0.3 3e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEQ30141.1 - 2.1e-08 34.0 0.0 3.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEQ30141.1 - 0.0025 18.2 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldedh PF00171.17 EEQ30142.1 - 1.5e-185 616.9 0.1 1.7e-185 616.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Metallophos PF00149.23 EEQ30143.1 - 1.4e-36 125.8 0.0 4.8e-36 124.0 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase 2OG-FeII_Oxy PF03171.15 EEQ30144.1 - 1.9e-09 37.6 0.0 1.2e-08 35.1 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EEQ30144.1 - 3.3e-08 34.0 0.0 7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ctr PF04145.10 EEQ30145.1 - 2.4e-35 121.6 0.0 3.4e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 EEQ30145.1 - 0.055 13.0 0.4 0.11 12.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF2946 PF11162.3 EEQ30145.1 - 2.7 8.2 6.5 7.5 6.7 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Smg4_UPF3 PF03467.10 EEQ30146.1 - 1.5e-23 83.7 0.0 1.5e-21 77.1 0.0 2.5 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 EEQ30146.1 - 3.2e-08 33.0 0.6 1.4e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ30146.1 - 3.6e-07 30.0 0.0 1.3e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ30146.1 - 2.1e-06 27.4 0.0 5.9e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EEQ30146.1 - 2.1 6.7 39.2 3.6 5.9 27.1 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CrtC PF07143.6 EEQ30147.1 - 1e-19 71.0 1.1 1.4e-18 67.2 0.8 2.0 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Tocopherol_cycl PF14249.1 EEQ30147.1 - 0.0017 17.1 0.3 0.0026 16.5 0.2 1.2 1 0 0 1 1 1 1 Tocopherol cyclase zf-C2H2 PF00096.21 EEQ30148.1 - 6.7e-11 41.8 13.7 7.9e-06 25.9 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ30148.1 - 5.2e-08 32.6 8.9 3.9e-05 23.6 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ30148.1 - 5.4e-08 32.7 8.6 2.2e-06 27.6 1.6 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EEQ30148.1 - 0.00034 20.6 5.4 0.38 11.0 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ30148.1 - 0.0018 18.3 9.0 0.015 15.4 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ30148.1 - 0.0019 18.0 4.9 0.54 10.2 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EEQ30148.1 - 0.0051 16.5 3.8 0.031 14.0 0.3 2.3 2 0 0 2 2 2 1 BED zinc finger SprT-like PF10263.4 EEQ30148.1 - 0.017 14.7 0.2 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 SprT-like family zf-C2HC_2 PF13913.1 EEQ30148.1 - 5.2 6.8 10.1 0.49 10.1 1.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 EEQ30148.1 - 6.5 7.1 20.0 0.091 13.0 1.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain p450 PF00067.17 EEQ30150.1 - 1.4e-60 205.1 0.0 1.9e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GATA PF00320.22 EEQ30152.1 - 1e-15 56.7 1.1 2e-15 55.8 0.8 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EEQ30152.1 - 0.13 11.6 0.2 0.36 10.1 0.1 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding F-box PF00646.28 EEQ30154.1 - 1.3e-06 27.8 0.1 3.9e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ30154.1 - 0.00055 19.6 0.3 0.0016 18.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EEQ30154.1 - 0.027 14.4 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 PRANC domain Cys_rich_CPCC PF14206.1 EEQ30154.1 - 0.047 13.2 0.6 0.047 13.2 0.4 2.1 2 0 0 2 2 2 0 Cysteine-rich CPCC Zn_clus PF00172.13 EEQ30156.1 - 7.2e-08 32.2 6.8 1e-07 31.7 4.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.13 EEQ30157.1 - 1.6e-09 37.3 0.0 1.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEQ30157.1 - 0.00043 20.0 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family KRE9 PF05390.6 EEQ30157.1 - 0.067 13.5 0.9 0.1 12.9 0.2 1.6 2 0 0 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 zf-AN1 PF01428.11 EEQ30159.1 - 8.7e-12 44.7 11.2 1.2e-11 44.2 7.8 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4187 PF13821.1 EEQ30159.1 - 0.13 11.8 2.4 0.22 11.1 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Haemolytic PF01809.13 EEQ30159.1 - 0.17 11.5 1.9 0.22 11.1 1.3 1.2 1 0 0 1 1 1 0 Haemolytic domain Transp_Tc5_C PF04236.10 EEQ30159.1 - 0.42 10.8 5.2 0.22 11.7 2.4 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF1754 PF08555.5 EEQ30160.1 - 4e-16 59.3 21.3 4e-16 59.3 14.8 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF2984 PF11203.3 EEQ30160.1 - 0.21 11.7 2.1 0.25 11.4 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2984) SPX PF03105.14 EEQ30160.1 - 0.27 11.0 10.2 0.32 10.7 7.1 1.0 1 0 0 1 1 1 0 SPX domain CMV_1a PF12467.3 EEQ30160.1 - 0.74 10.1 9.2 0.94 9.8 6.4 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF3827 PF12877.2 EEQ30160.1 - 1.2 7.1 8.6 1.4 6.8 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Adaptin_binding PF10199.4 EEQ30160.1 - 1.4 9.1 13.8 2 8.6 9.5 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Daxx PF03344.10 EEQ30160.1 - 1.5 7.1 15.4 1.7 7.0 10.7 1.0 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 EEQ30160.1 - 2.9 7.2 15.8 3.7 6.9 10.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO NAM-associated PF14303.1 EEQ30160.1 - 3.4 7.9 21.1 4.2 7.6 14.6 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF1510 PF07423.6 EEQ30160.1 - 5.7 6.2 17.1 9 5.5 11.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EEQ30160.1 - 6.5 4.6 20.5 7.8 4.3 14.2 1.0 1 0 0 1 1 1 0 CDC45-like protein HSP70 PF00012.15 EEQ30160.1 - 6.6 4.5 13.5 7.4 4.3 9.3 1.0 1 0 0 1 1 1 0 Hsp70 protein PTPA PF03095.10 EEQ30161.1 - 1.1e-97 326.8 0.1 1.4e-94 316.7 0.1 2.0 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF202 PF02656.10 EEQ30162.1 - 7.4e-09 35.7 0.1 7.4e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SAGA-Tad1 PF12767.2 EEQ30162.1 - 0.44 10.1 3.7 1 8.9 2.6 1.7 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Dicty_REP PF05086.7 EEQ30165.1 - 1.8 6.2 9.6 3.1 5.4 6.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3115 PF11312.3 EEQ30167.1 - 3.6e-86 288.8 0.0 4.8e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Ndr PF03096.9 EEQ30167.1 - 0.062 11.7 0.1 5.6 5.3 0.0 2.2 2 0 0 2 2 2 0 Ndr family CSTF_C PF14304.1 EEQ30167.1 - 0.2 10.9 0.5 3.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Band_7 PF01145.20 EEQ30168.1 - 4.5e-24 85.3 7.5 6.5e-24 84.8 4.9 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family GatB_Yqey PF02637.13 EEQ30168.1 - 0.024 14.3 0.4 0.042 13.5 0.3 1.4 1 0 0 1 1 1 0 GatB domain DUF2884 PF11101.3 EEQ30168.1 - 0.028 13.8 0.4 0.049 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) UcrQ PF02939.11 EEQ30169.1 - 8.5e-27 92.8 0.2 9.8e-27 92.6 0.1 1.0 1 0 0 1 1 1 1 UcrQ family Ribosomal_L7Ae PF01248.21 EEQ30170.1 - 3.1e-15 55.4 0.1 7.2e-15 54.2 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3455 PF11937.3 EEQ30170.1 - 0.014 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Avirulence PF03377.8 EEQ30170.1 - 0.016 13.9 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA MMR_HSR1_C PF08438.5 EEQ30172.1 - 3.5e-32 110.8 0.0 7.3e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EEQ30172.1 - 1e-14 54.4 0.0 2.5e-14 53.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ30172.1 - 8.8e-06 25.0 0.0 0.00035 19.8 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EEQ30172.1 - 0.0022 17.4 0.2 0.56 9.6 0.0 2.8 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EEQ30172.1 - 0.011 15.5 2.7 0.24 11.2 0.4 2.8 3 0 0 3 3 3 0 Dynamin family ABC_tran PF00005.22 EEQ30172.1 - 0.043 14.1 0.2 0.65 10.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 EEQ30172.1 - 0.055 12.2 0.5 0.23 10.2 0.1 2.1 2 0 0 2 2 2 0 ArgK protein VirB8 PF04335.8 EEQ30172.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein AAA_30 PF13604.1 EEQ30172.1 - 0.079 12.5 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EEQ30172.1 - 0.092 11.9 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.12 EEQ30172.1 - 0.095 12.2 0.3 8.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SET PF00856.23 EEQ30174.1 - 0.074 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 SET domain Big_3_4 PF13754.1 EEQ30175.1 - 0.06 13.6 2.0 0.1 12.9 1.4 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) zf-C4 PF00105.13 EEQ30175.1 - 0.072 13.3 0.1 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Fungal_trans PF04082.13 EEQ30176.1 - 1.4e-32 112.5 0.4 2.7e-32 111.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ30176.1 - 1e-09 38.0 11.7 1.8e-09 37.3 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 EEQ30176.1 - 3.1 5.9 4.9 8.4 4.5 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein Transketolase_N PF00456.16 EEQ30177.1 - 5.7e-148 492.1 0.0 7.7e-148 491.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EEQ30177.1 - 7.6e-46 155.8 0.0 1.2e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEQ30177.1 - 2.3e-14 53.3 0.0 4.7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EEQ30177.1 - 8.1e-07 28.2 0.0 0.00043 19.3 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EEQ30177.1 - 0.012 14.3 0.1 0.021 13.5 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Spermine_synth PF01564.12 EEQ30178.1 - 1.5e-93 312.2 0.0 1.9e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EEQ30178.1 - 0.00056 19.5 0.0 0.00082 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EEQ30178.1 - 0.0015 17.5 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 EEQ30178.1 - 0.0016 18.9 0.2 0.0075 16.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ30178.1 - 0.0026 18.2 0.0 0.0046 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ30178.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EEQ30178.1 - 0.055 13.1 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain bZIP_1 PF00170.16 EEQ30179.1 - 4.8e-08 32.8 9.7 7.8e-08 32.1 6.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor TMF_TATA_bd PF12325.3 EEQ30179.1 - 8.8e-05 22.2 1.5 0.00013 21.6 1.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.10 EEQ30179.1 - 0.00094 18.9 11.3 0.0019 18.0 5.9 2.2 1 1 1 2 2 2 1 Basic region leucine zipper ASD2 PF08687.6 EEQ30179.1 - 0.0036 16.6 1.4 0.0046 16.3 1.0 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 EAP30 PF04157.11 EEQ30179.1 - 0.022 13.9 3.9 0.03 13.4 2.7 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family TMF_DNA_bd PF12329.3 EEQ30179.1 - 0.033 13.9 2.2 0.053 13.3 1.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_Maf PF03131.12 EEQ30179.1 - 0.04 14.2 15.0 0.099 12.9 10.4 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF948 PF06103.6 EEQ30179.1 - 0.051 13.4 0.1 0.077 12.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4254 PF14063.1 EEQ30179.1 - 0.071 12.7 2.6 0.11 12.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Macoilin PF09726.4 EEQ30179.1 - 0.075 11.3 6.1 0.098 10.9 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein TBPIP PF07106.8 EEQ30179.1 - 0.083 12.4 1.7 0.13 11.7 1.2 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2400 PF09674.5 EEQ30179.1 - 0.09 12.4 0.5 0.13 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) IncA PF04156.9 EEQ30179.1 - 0.15 11.6 4.9 0.19 11.2 3.4 1.1 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 EEQ30179.1 - 0.29 10.7 3.9 0.42 10.2 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CcmH PF03918.9 EEQ30179.1 - 0.67 8.9 4.0 0.27 10.2 1.1 1.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein G-alpha PF00503.15 EEQ30184.1 - 8.5e-113 376.9 0.0 1e-112 376.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEQ30184.1 - 1.2e-13 50.6 1.2 4.5e-09 35.7 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ30184.1 - 1.1e-06 27.9 0.0 0.0018 17.4 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EEQ30184.1 - 0.0035 17.8 0.1 0.28 11.7 0.0 2.9 2 2 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EEQ30184.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEQ30184.1 - 0.054 13.4 0.0 7.9 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ30184.1 - 0.081 12.3 0.0 4 6.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pet20 PF08692.5 EEQ30185.1 - 0.24 11.3 0.0 0.24 11.3 0.0 1.9 3 0 0 3 3 3 0 Mitochondrial protein Pet20 ATP-synt_C PF00137.16 EEQ30186.1 - 2e-33 114.1 29.2 3.8e-19 68.3 8.9 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EEQ30186.1 - 0.18 11.3 2.9 0.11 12.0 0.4 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A ABA_GPCR PF12430.3 EEQ30186.1 - 0.21 10.6 1.1 3.3 6.7 0.1 2.1 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor Transferase PF02458.10 EEQ30188.1 - 5.3e-30 104.2 0.0 2.4e-16 59.2 0.0 3.4 4 0 0 4 4 4 3 Transferase family GSHPx PF00255.14 EEQ30192.1 - 5.4e-40 135.1 0.0 7e-40 134.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EEQ30192.1 - 0.0076 15.9 0.0 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEQ30192.1 - 0.015 14.8 0.2 0.098 12.2 0.2 2.3 1 1 0 1 1 1 0 Redoxin SCO1-SenC PF02630.9 EEQ30192.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 SCO1/SenC DUF4545 PF15078.1 EEQ30193.1 - 0.028 13.3 1.4 0.031 13.1 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) Striatin PF08232.7 EEQ30193.1 - 0.14 12.4 2.4 0.18 12.1 1.6 1.3 1 0 0 1 1 1 0 Striatin family Hydrolase_6 PF13344.1 EEQ30194.1 - 1.2e-23 82.8 0.0 2.6e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ30194.1 - 2.5e-10 39.9 0.0 1.7e-09 37.2 0.0 2.5 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 EEQ30194.1 - 0.039 14.3 0.0 0.72 10.2 0.0 2.5 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEQ30194.1 - 0.1 12.7 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF676 PF05057.9 EEQ30195.1 - 8.1e-49 165.8 0.0 1.3e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EEQ30195.1 - 3.3e-05 23.6 0.0 7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EEQ30195.1 - 4.3e-05 23.1 0.0 8.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EEQ30195.1 - 0.00018 21.5 0.2 0.00051 19.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EEQ30195.1 - 0.0054 16.1 0.0 0.039 13.3 0.0 2.0 2 0 0 2 2 2 1 PE-PPE domain PGAP1 PF07819.8 EEQ30195.1 - 0.0082 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF3951 PF13131.1 EEQ30195.1 - 0.31 10.8 3.8 0.78 9.5 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) RNase_T PF00929.19 EEQ30196.1 - 6e-10 39.6 0.0 1.9e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Exonuclease BTK PF00779.14 EEQ30196.1 - 0.085 12.4 0.6 0.16 11.5 0.4 1.4 1 0 0 1 1 1 0 BTK motif Ribosomal_L22e PF01776.12 EEQ30197.1 - 7.6e-49 164.3 0.9 9.3e-49 164.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF1160 PF06648.6 EEQ30197.1 - 0.1 12.3 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Translin PF01997.11 EEQ30198.1 - 4.3e-53 179.9 0.0 4.9e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Translin family Herpes_UL25 PF01499.11 EEQ30198.1 - 0.006 14.9 0.0 0.0081 14.5 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL25 family GMP_synt_C PF00958.17 EEQ30198.1 - 0.032 13.9 0.0 0.1 12.3 0.0 2.0 1 1 1 2 2 2 0 GMP synthase C terminal domain HR1 PF02185.11 EEQ30198.1 - 0.052 13.2 0.4 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Hr1 repeat Syntaxin-6_N PF09177.6 EEQ30198.1 - 0.054 13.8 0.2 0.18 12.2 0.1 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DisA-linker PF10635.4 EEQ30198.1 - 0.075 12.5 0.1 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region DUF1938 PF09153.5 EEQ30198.1 - 0.11 12.3 0.1 0.54 10.1 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1938) Syntaxin PF00804.20 EEQ30198.1 - 0.13 12.4 0.8 2.5 8.2 0.3 2.4 2 1 0 2 2 2 0 Syntaxin Pcc1 PF09341.5 EEQ30199.1 - 7e-23 80.4 3.9 2.2e-22 78.8 2.7 1.7 1 1 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 EEQ30201.1 - 7.9e-41 139.3 0.0 8.1e-38 129.5 0.0 3.1 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EEQ30201.1 - 7.3e-16 57.9 0.0 1.9e-15 56.6 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEQ30201.1 - 2.1e-05 24.0 0.0 3.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EEQ30201.1 - 0.2 11.0 0.0 0.7 9.2 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Pyridoxal_deC PF00282.14 EEQ30203.1 - 4.7e-58 196.4 0.0 6.9e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EEQ30203.1 - 0.16 10.6 0.0 0.37 9.4 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-V DUF917 PF06032.7 EEQ30204.1 - 3.3e-104 348.2 0.1 7.7e-104 347.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EEQ30204.1 - 2.1e-51 174.7 5.2 9e-50 169.3 1.6 2.6 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEQ30204.1 - 3.4e-27 95.0 0.2 6.6e-26 90.8 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EEQ30204.1 - 0.00042 18.7 1.1 0.074 11.3 0.1 3.1 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.15 EEQ30204.1 - 0.026 13.8 4.4 0.036 13.3 0.0 3.1 3 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DUF1624 PF07786.7 EEQ30204.1 - 0.37 10.0 0.0 0.61 9.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Homeobox PF00046.24 EEQ30205.1 - 1.5e-12 46.9 0.0 3.9e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain MFS_1 PF07690.11 EEQ30206.1 - 1.5e-34 119.3 20.9 6.3e-29 100.7 11.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EEQ30206.1 - 0.00022 19.4 1.8 0.0044 15.1 0.2 2.4 1 1 1 2 2 2 2 Transmembrane secretion effector OATP PF03137.15 EEQ30206.1 - 0.26 9.3 6.9 3.6 5.5 1.9 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF443 PF04276.7 EEQ30206.1 - 9.1 5.6 10.8 0.061 12.7 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF443) Fungal_trans_2 PF11951.3 EEQ30207.1 - 6.6e-57 192.8 0.0 8.5e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ30207.1 - 2.3e-07 30.5 12.0 4.4e-07 29.7 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 EEQ30208.1 - 2.6e-41 141.5 0.0 3.7e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.20 EEQ30209.1 - 3.3e-56 190.3 0.1 3.6e-55 186.9 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30209.1 - 6.5e-29 100.7 0.4 1.8e-20 73.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EEQ30209.1 - 5.5e-06 26.7 0.3 1.2e-05 25.6 0.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEQ30209.1 - 5.4e-05 22.2 0.1 0.00051 19.0 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ30209.1 - 0.00085 19.1 5.2 0.24 11.1 0.0 3.5 1 1 2 3 3 3 2 Phosphotransferase enzyme family DUF1687 PF07955.6 EEQ30210.1 - 1.8e-14 53.8 0.1 7.2e-14 51.9 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Abhydrolase_2 PF02230.11 EEQ30211.1 - 6.6e-57 192.4 0.0 7.7e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEQ30211.1 - 2e-08 34.1 0.0 3.4e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ30211.1 - 2e-07 30.4 0.0 2e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EEQ30211.1 - 1.6e-05 24.3 0.0 2.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EEQ30211.1 - 5.1e-05 22.9 0.0 0.0045 16.5 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ30211.1 - 0.00017 21.5 0.1 0.5 10.1 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EEQ30211.1 - 0.0084 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.8 EEQ30211.1 - 0.012 15.0 0.0 0.033 13.6 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.9 EEQ30211.1 - 0.039 13.1 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 Secretory lipase Esterase_phd PF10503.4 EEQ30211.1 - 0.049 12.8 0.0 0.67 9.1 0.0 2.4 3 0 0 3 3 3 0 Esterase PHB depolymerase Lipase_3 PF01764.20 EEQ30211.1 - 0.094 12.3 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ctr PF04145.10 EEQ30213.1 - 4.5e-30 104.5 0.1 5.5e-30 104.3 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FAD_binding_8 PF08022.7 EEQ30214.1 - 3.5e-20 71.8 0.0 8.4e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EEQ30214.1 - 1.5e-16 60.6 0.0 4.6e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EEQ30214.1 - 6.9e-14 52.0 11.4 2e-13 50.5 7.9 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EEQ30214.1 - 1.6e-05 24.9 0.0 4.9e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_3 PF01494.14 EEQ30215.1 - 1.6e-67 228.0 0.0 1.7e-38 132.6 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 EEQ30215.1 - 3.5e-05 23.4 0.0 0.00012 21.6 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EEQ30215.1 - 0.032 13.0 0.0 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Nup35_RRM PF05172.8 EEQ30216.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif EF-1_beta_acid PF10587.4 EEQ30217.1 - 0.02 15.0 3.1 0.02 15.0 2.1 2.2 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Snf7 PF03357.16 EEQ30218.1 - 0.01 15.2 0.8 0.021 14.2 0.5 1.6 1 1 0 1 1 1 0 Snf7 DUF2365 PF10157.4 EEQ30218.1 - 0.017 15.0 0.4 0.02 14.7 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) BLOC1_2 PF10046.4 EEQ30218.1 - 0.021 14.9 0.8 0.086 12.9 0.4 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1741 PF08427.5 EEQ30218.1 - 0.03 13.7 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) IncA PF04156.9 EEQ30218.1 - 0.072 12.6 5.8 0.1 12.1 4.0 1.4 1 1 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 EEQ30218.1 - 0.089 12.8 0.5 0.15 12.0 0.2 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.1 EEQ30218.1 - 0.11 12.8 3.7 2.6 8.4 0.4 2.4 1 1 1 2 2 2 0 Snapin/Pallidin Wbp11 PF09429.5 EEQ30220.1 - 1.2e-23 82.8 16.5 1.2e-23 82.8 11.4 1.8 2 0 0 2 2 2 1 WW domain binding protein 11 SynMuv_product PF06047.6 EEQ30220.1 - 0.092 12.4 0.3 0.092 12.4 0.2 2.4 2 1 0 2 2 2 0 Ras-induced vulval development antagonist Pkinase PF00069.20 EEQ30221.1 - 2.8e-59 200.3 0.0 4.9e-59 199.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30221.1 - 2.1e-36 125.3 0.0 2.2e-35 121.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Reo_sigmaC PF04582.7 EEQ30221.1 - 0.024 13.8 0.5 0.037 13.2 0.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PIN_2 PF10130.4 EEQ30221.1 - 0.13 12.2 2.6 0.35 10.9 1.8 1.8 1 1 0 1 1 1 0 PIN domain DUF607 PF04678.8 EEQ30221.1 - 0.27 11.1 5.1 0.21 11.5 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF607 BTB PF00651.26 EEQ30222.1 - 1.4e-27 95.8 0.0 3e-14 52.9 0.1 2.8 2 0 0 2 2 2 2 BTB/POZ domain DUF2633 PF11119.3 EEQ30222.1 - 0.16 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) TRP PF06011.7 EEQ30223.1 - 5.4e-64 216.3 24.3 7.2e-63 212.6 16.9 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEQ30223.1 - 4.3e-27 94.8 0.0 7.6e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 ML-like domain PhoQ_Sensor PF08918.5 EEQ30223.1 - 0.068 12.6 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoQ Sensor Pkinase PF00069.20 EEQ30224.1 - 1.3e-25 90.0 0.0 3.3e-25 88.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30224.1 - 1.2e-05 24.5 0.0 0.0063 15.6 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Wound_ind PF08186.6 EEQ30227.1 - 0.055 13.3 2.4 0.25 11.2 0.2 2.2 2 0 0 2 2 2 0 Wound-inducible basic protein family zf-C2H2 PF00096.21 EEQ30229.1 - 5.3e-09 35.8 11.3 0.00038 20.6 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ30229.1 - 5.2e-06 26.4 10.6 6.2e-06 26.2 0.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ30229.1 - 0.00013 22.0 9.8 0.0083 16.3 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EEQ30229.1 - 0.011 15.8 2.9 0.025 14.7 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EEQ30229.1 - 0.14 12.1 1.7 3.7 7.5 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 EEQ30229.1 - 0.36 11.0 5.2 0.65 10.2 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EEQ30229.1 - 0.86 9.4 8.3 1.7 8.4 1.0 2.5 2 1 0 2 2 2 0 BED zinc finger PAT1 PF09770.4 EEQ30229.1 - 1.4 7.1 10.4 1.6 6.8 7.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 adh_short PF00106.20 EEQ30230.1 - 9.2e-17 61.4 0.0 1.8e-14 54.0 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ30230.1 - 1.3e-08 34.6 0.0 2.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEQ30230.1 - 0.037 12.9 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEQ30230.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAC PF01849.13 EEQ30231.1 - 1.3e-23 82.2 1.1 6e-23 80.1 0.5 2.1 2 0 0 2 2 2 1 NAC domain Rpr2 PF04032.11 EEQ30232.1 - 1.3e-19 69.8 6.6 4.5e-19 68.1 4.5 1.8 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.24 EEQ30233.1 - 5.1e-34 117.2 0.0 8.5e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ30233.1 - 6.8e-25 86.7 0.1 2.8e-23 81.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ30233.1 - 1.4e-07 31.5 0.0 3.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEQ30233.1 - 0.00058 19.0 0.1 0.0043 16.1 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 EEQ30233.1 - 0.019 14.3 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain BNR_2 PF13088.1 EEQ30233.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain Ank_2 PF12796.2 EEQ30234.1 - 6.4e-50 167.4 4.5 2.6e-10 40.4 0.0 7.1 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ30234.1 - 4e-42 141.8 9.6 8.1e-09 35.7 0.0 10.3 6 2 3 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.25 EEQ30234.1 - 5e-36 120.7 15.7 6.1e-05 22.6 0.0 11.9 10 1 1 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 EEQ30234.1 - 7.2e-32 108.7 11.6 5.2e-07 29.6 0.0 8.1 4 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ30234.1 - 5.1e-25 85.0 9.0 0.049 13.8 0.0 12.3 11 1 1 12 12 12 7 Ankyrin repeat ApbA PF02558.11 EEQ30236.1 - 3.7e-24 84.8 0.0 5.8e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EEQ30236.1 - 4e-21 75.2 0.1 6.7e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 EEQ30237.1 - 3.8e-20 71.7 4.1 5.2e-20 71.3 2.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like H-kinase_dim PF02895.9 EEQ30238.1 - 0.0076 16.5 0.9 0.013 15.7 0.6 1.4 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain BBS2_C PF14782.1 EEQ30238.1 - 0.0087 14.6 3.7 0.01 14.4 2.6 1.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal Fzo_mitofusin PF04799.8 EEQ30238.1 - 0.36 10.2 5.5 0.49 9.7 3.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region Lipase_3 PF01764.20 EEQ30239.1 - 1.2e-15 57.4 0.0 7.4e-15 54.8 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEQ30239.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family RGS PF00615.14 EEQ30240.1 - 1.6e-07 31.4 0.0 0.00039 20.5 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF2892 PF11127.3 EEQ30240.1 - 0.5 10.2 3.1 1.6 8.6 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) SMC_N PF02463.14 EEQ30241.1 - 1.8e-21 76.3 0.1 2.7e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEQ30241.1 - 1.1e-19 71.5 0.0 1.1e-19 71.5 0.0 5.1 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.1 EEQ30241.1 - 1.4e-05 25.2 0.0 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ30241.1 - 0.0024 17.3 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EEQ30241.1 - 0.21 10.9 0.0 0.21 10.9 0.0 2.8 3 1 1 4 4 4 0 AAA domain Baculo_PEP_C PF04513.7 EEQ30241.1 - 0.46 10.2 15.8 3.2 7.5 0.2 5.1 3 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EEQ30241.1 - 2.1 8.6 13.5 5.9 7.2 0.2 5.1 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Adeno_E4_34 PF04528.8 EEQ30241.1 - 2.8 7.5 6.9 9.5 5.7 0.3 3.0 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region AdoMet_MTase PF07757.8 EEQ30242.1 - 3e-36 123.9 0.3 9.9e-34 115.8 0.2 2.3 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase DUF3237 PF11578.3 EEQ30243.1 - 2.2e-33 114.6 0.0 3.1e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 EEQ30243.1 - 0.011 15.5 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 BED zinc finger Gln-synt_C PF00120.19 EEQ30244.1 - 3.6e-45 154.1 0.0 2.6e-37 128.3 0.0 2.5 2 1 0 2 2 2 2 Glutamine synthetase, catalytic domain adh_short PF00106.20 EEQ30245.1 - 2.6e-28 99.0 1.9 3.6e-28 98.5 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ30245.1 - 1.5e-15 57.6 0.0 1.9e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ30245.1 - 7.9e-12 45.2 1.1 1.4e-11 44.4 0.8 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EEQ30245.1 - 0.00023 20.8 0.3 0.00042 20.0 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EEQ30245.1 - 0.001 18.5 0.1 0.0016 17.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EEQ30245.1 - 0.012 16.1 0.0 0.05 14.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_10 PF13460.1 EEQ30245.1 - 0.012 15.5 1.2 0.03 14.3 0.7 1.7 1 1 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 EEQ30245.1 - 0.025 13.5 0.2 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EEQ30245.1 - 0.06 13.1 2.6 0.37 10.6 0.4 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ldh_1_N PF00056.18 EEQ30245.1 - 0.067 13.0 0.9 0.31 10.8 0.5 2.0 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EEQ30245.1 - 0.11 11.5 0.8 0.19 10.7 0.2 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain gag_pre-integrs PF13976.1 EEQ30247.1 - 3.6e-05 23.3 0.0 6.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain CBP4 PF07960.6 EEQ30248.1 - 2.6e-35 120.8 3.3 3e-35 120.6 2.3 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 EEQ30248.1 - 0.0072 16.0 1.1 0.015 14.9 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4574) Trp_oprn_chp PF09534.5 EEQ30248.1 - 0.068 12.7 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3683 PF12447.3 EEQ30248.1 - 0.16 11.8 1.9 0.23 11.2 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) COX6A PF02046.10 EEQ30248.1 - 1.1 9.2 5.1 0.26 11.2 1.1 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIa Glyco_hydro_76 PF03663.9 EEQ30249.1 - 3.4e-152 507.1 17.5 4.4e-152 506.7 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EEQ30249.1 - 0.0023 17.0 10.2 0.015 14.3 0.2 3.2 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Rad21_Rec8_N PF04825.8 EEQ30250.1 - 4.6e-30 103.8 0.0 7.8e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EEQ30250.1 - 0.0047 16.0 0.0 0.0094 15.1 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF4006 PF13179.1 EEQ30250.1 - 0.019 14.5 0.3 0.039 13.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF619 PF04768.8 EEQ30251.1 - 1e-50 171.4 0.0 2.4e-50 170.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EEQ30251.1 - 3.8e-30 104.6 0.0 1.1e-29 103.1 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EEQ30251.1 - 1.3e-24 87.1 0.0 2.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EEQ30251.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 EEQ30252.1 - 8.3e-33 111.8 1.5 9.5e-33 111.6 1.0 1.0 1 0 0 1 1 1 1 Synaptobrevin CDP-OH_P_transf PF01066.16 EEQ30252.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.3 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase EMP24_GP25L PF01105.19 EEQ30252.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1035 PF06281.7 EEQ30252.1 - 0.18 11.6 2.3 0.28 10.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) Sel1 PF08238.7 EEQ30254.1 - 7.9e-46 153.4 24.2 7.1e-08 32.8 0.1 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.1 EEQ30254.1 - 0.13 12.7 4.3 0.73 10.4 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat LigB PF02900.13 EEQ30255.1 - 1.2e-46 158.9 0.0 1.5e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.11 EEQ30256.1 - 1.3e-10 40.7 0.1 1.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 EEQ30257.1 - 1.3e-44 151.0 0.2 1.9e-44 150.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) FAD_binding_3 PF01494.14 EEQ30258.1 - 3.7e-22 78.8 0.9 1.3e-13 50.7 0.5 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEQ30258.1 - 0.00015 21.6 0.0 0.00059 19.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ30258.1 - 0.00016 20.7 0.0 0.01 14.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEQ30258.1 - 0.00043 20.6 0.0 0.022 15.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ30258.1 - 0.0026 16.6 0.3 0.0073 15.2 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EEQ30258.1 - 0.0066 15.3 0.0 0.012 14.5 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EEQ30258.1 - 0.011 15.3 0.0 0.047 13.3 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EEQ30258.1 - 0.039 13.0 0.0 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EEQ30258.1 - 0.057 11.8 0.2 0.44 8.9 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EEQ30258.1 - 0.093 11.6 0.3 0.42 9.4 0.1 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EEQ30258.1 - 0.098 12.2 0.4 0.19 11.3 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_23 PF13489.1 EEQ30259.1 - 2.6e-23 82.4 0.2 5.6e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ30259.1 - 4.5e-12 46.2 0.0 9.2e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ30259.1 - 4e-11 42.7 0.0 2.3e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ30259.1 - 1.2e-09 38.5 0.0 5.7e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ30259.1 - 3.7e-09 37.1 0.0 6.6e-08 33.1 0.0 2.6 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ30259.1 - 9.9e-05 22.6 0.0 0.00036 20.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ30259.1 - 0.00013 22.0 0.0 0.00032 20.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEQ30259.1 - 0.00014 21.0 0.0 0.00022 20.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EEQ30259.1 - 0.00022 20.4 0.0 0.004 16.2 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EEQ30259.1 - 0.0015 17.7 0.0 0.0071 15.5 0.0 2.1 3 0 0 3 3 3 1 O-methyltransferase MTS PF05175.9 EEQ30259.1 - 0.0034 16.7 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EEQ30259.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EEQ30259.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EEQ30259.1 - 0.027 13.4 0.0 0.076 12.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.4 EEQ30259.1 - 0.03 13.7 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Mid2 PF04478.7 EEQ30260.1 - 0.00028 20.3 0.9 0.00042 19.7 0.6 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Podoplanin PF05808.6 EEQ30260.1 - 0.0033 17.0 1.7 0.0064 16.0 1.2 1.4 1 0 0 1 1 1 1 Podoplanin DUF575 PF04746.7 EEQ30260.1 - 0.0037 17.2 0.5 0.0063 16.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF575) gpUL132 PF11359.3 EEQ30260.1 - 0.012 14.9 1.0 0.018 14.4 0.7 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DUF1517 PF07466.6 EEQ30260.1 - 0.013 14.5 3.5 0.017 14.1 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) TrbC PF04956.8 EEQ30260.1 - 0.017 15.1 0.6 0.027 14.4 0.4 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family CD99L2 PF12301.3 EEQ30260.1 - 0.11 12.1 2.1 0.27 10.9 1.4 1.6 2 0 0 2 2 2 0 CD99 antigen like protein 2 RAP1 PF07218.6 EEQ30260.1 - 2.5 6.0 13.0 3.5 5.6 9.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Malate_synthase PF01274.17 EEQ30261.1 - 6.9e-231 766.7 0.0 7.8e-231 766.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase PsbH PF00737.15 EEQ30262.1 - 0.015 14.8 0.9 0.034 13.7 0.0 2.0 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Pyr_redox_3 PF13738.1 EEQ30263.1 - 2.5e-18 66.8 0.0 5.4e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ30263.1 - 5.4e-16 57.8 0.1 1.9e-12 46.1 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EEQ30263.1 - 1.8e-11 43.8 0.1 7.3e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEQ30263.1 - 6.5e-05 22.0 0.1 0.0049 15.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EEQ30263.1 - 0.0047 15.8 0.0 0.17 10.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEQ30263.1 - 0.0098 15.6 0.1 0.049 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EEQ30263.1 - 0.032 13.3 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EEQ30263.1 - 0.072 13.5 0.2 2 8.8 0.0 3.2 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ30263.1 - 0.11 10.8 0.1 0.25 9.7 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_3 PF00933.16 EEQ30264.1 - 6.8e-88 294.4 0.0 9.7e-88 293.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEQ30264.1 - 1.3e-51 175.3 0.1 3.4e-50 170.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEQ30264.1 - 4.2e-19 68.2 0.0 8.3e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Serpin PF00079.15 EEQ30266.1 - 1.1e-56 192.6 0.0 1.2e-56 192.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) AA_permease_2 PF13520.1 EEQ30267.1 - 8.8e-49 166.1 56.0 1e-48 165.9 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ30267.1 - 3.7e-20 71.7 41.8 5.1e-20 71.2 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_18 PF00704.23 EEQ30269.1 - 4e-70 236.9 0.3 5.6e-70 236.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EEQ30269.1 - 2.4e-08 33.8 7.3 2.4e-08 33.8 5.1 3.2 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.15 EEQ30269.1 - 4.3e-05 23.3 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 LysM domain Aspzincin_M35 PF14521.1 EEQ30270.1 - 0.00029 21.3 0.0 0.00089 19.7 0.0 1.9 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EEQ30270.1 - 0.073 12.4 0.0 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative peptidase family Peptidase_M35 PF02102.10 EEQ30270.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family F-box PF00646.28 EEQ30271.1 - 0.00028 20.4 1.2 0.00082 18.9 0.9 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ30271.1 - 0.084 12.6 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like GST_N_3 PF13417.1 EEQ30272.1 - 1.7e-09 37.7 0.0 4.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ30272.1 - 5.3e-08 32.7 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ30272.1 - 1.9e-07 30.8 0.3 4.9e-07 29.5 0.1 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEQ30272.1 - 0.00018 21.4 0.0 0.00036 20.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ30272.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.22 EEQ30273.1 - 2.4e-45 154.1 0.1 1.9e-24 86.5 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEQ30273.1 - 9.3e-15 55.3 2.3 0.013 15.5 0.0 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 EEQ30273.1 - 1.1e-10 41.1 0.3 0.0031 16.7 0.0 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EEQ30273.1 - 3.8e-07 30.0 0.0 0.047 13.6 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase Chromo PF00385.19 EEQ30273.1 - 6.4e-07 28.9 0.2 2.1e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF258 PF03193.11 EEQ30273.1 - 1.1e-06 27.9 0.0 0.02 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EEQ30273.1 - 1.4e-06 27.6 0.0 0.11 11.5 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EEQ30273.1 - 2.2e-06 27.0 1.8 0.04 13.4 0.6 2.8 2 1 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ30273.1 - 4.6e-06 27.4 0.0 0.1 13.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EEQ30273.1 - 8.2e-06 26.3 0.1 0.029 14.8 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein AAA_23 PF13476.1 EEQ30273.1 - 1e-05 25.9 0.7 0.02 15.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EEQ30273.1 - 1.2e-05 25.0 0.0 0.39 10.6 0.0 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EEQ30273.1 - 4.1e-05 23.7 0.9 0.14 12.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EEQ30273.1 - 6.2e-05 22.5 4.2 0.3 10.5 0.2 4.1 5 0 0 5 5 5 2 AAA-like domain NACHT PF05729.7 EEQ30273.1 - 7.7e-05 22.4 0.3 0.043 13.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.12 EEQ30273.1 - 0.00022 21.1 3.4 0.057 13.2 0.1 3.9 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_28 PF13521.1 EEQ30273.1 - 0.00035 20.5 0.1 0.016 15.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 EEQ30273.1 - 0.0012 18.5 0.1 1 9.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EEQ30273.1 - 0.0015 18.6 0.1 1.5 9.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 EEQ30273.1 - 0.0035 17.6 0.3 2.2 8.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 EEQ30273.1 - 0.012 15.1 0.0 5.4 6.4 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT PF02985.17 EEQ30273.1 - 0.013 15.4 0.7 61 4.0 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat AAA_25 PF13481.1 EEQ30273.1 - 0.015 14.6 0.0 5.9 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EEQ30273.1 - 0.016 15.0 0.0 5.9 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EEQ30273.1 - 0.02 13.6 0.3 5.2 5.7 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA PF00004.24 EEQ30273.1 - 0.022 14.9 0.4 2.1 8.5 0.0 3.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Adaptin_N PF01602.15 EEQ30273.1 - 0.023 13.0 0.5 0.13 10.5 0.2 1.9 2 0 0 2 2 2 0 Adaptin N terminal region PduV-EutP PF10662.4 EEQ30273.1 - 0.024 14.1 0.1 0.96 8.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EEQ30273.1 - 0.048 13.4 0.3 0.76 9.5 0.0 3.0 4 0 0 4 4 3 0 Dynamin family DUF3584 PF12128.3 EEQ30273.1 - 0.055 10.8 2.8 0.82 6.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EEQ30273.1 - 0.072 11.5 0.7 3.9 5.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EEQ30273.1 - 0.087 12.7 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEQ30273.1 - 0.13 11.8 2.8 3.1 7.3 0.2 3.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 EEQ30273.1 - 0.18 10.6 1.6 1.9 7.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Glyco_hydro_92 PF07971.7 EEQ30274.1 - 6.3e-168 559.5 0.0 7.9e-168 559.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Citrate_synt PF00285.16 EEQ30275.1 - 3.8e-79 266.0 0.0 7.2e-63 212.4 0.0 2.1 1 1 1 2 2 2 2 Citrate synthase ICL PF00463.16 EEQ30276.1 - 1.1e-197 657.4 0.0 1.3e-197 657.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EEQ30276.1 - 3.2e-12 46.1 0.0 3.2e-10 39.6 0.0 2.1 1 1 0 2 2 2 2 Phosphoenolpyruvate phosphomutase AMP-binding PF00501.23 EEQ30277.1 - 4.1e-70 236.2 0.0 5e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ30277.1 - 5.1e-10 40.1 0.2 1.3e-09 38.8 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.6 EEQ30277.1 - 0.12 11.8 0.4 0.28 10.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) MmgE_PrpD PF03972.9 EEQ30278.1 - 1.4e-149 498.0 0.0 1.6e-149 497.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DNA_methylase PF00145.12 EEQ30279.1 - 2.6e-36 125.4 0.0 1.4e-24 86.8 0.0 3.3 2 1 1 3 3 3 2 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 EEQ30279.1 - 0.022 14.8 0.0 0.077 13.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain GATase_2 PF00310.16 EEQ30280.1 - 4.5e-20 71.6 0.1 1.1e-15 57.2 0.0 2.9 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEQ30280.1 - 4.7e-14 52.4 0.0 1.1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EEQ30280.1 - 2.5e-13 49.8 0.0 6.8e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EEQ30280.1 - 3.2e-13 49.4 0.1 6.3e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EEQ30280.1 - 6e-06 25.1 0.0 1.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HhH-GPD PF00730.20 EEQ30281.1 - 5.3e-09 36.3 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Aldedh PF00171.17 EEQ30282.1 - 2e-119 399.0 0.0 2.4e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_6 PF12697.2 EEQ30283.1 - 1.9e-11 44.3 1.8 5.2e-11 42.8 1.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ30283.1 - 2.1e-10 40.5 0.1 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ30283.1 - 2.1e-07 30.7 0.1 6.8e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EEQ30283.1 - 0.00013 21.5 0.1 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ30283.1 - 0.00085 18.6 0.1 0.17 11.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EEQ30283.1 - 0.036 13.8 0.2 0.086 12.6 0.1 1.7 1 1 0 1 1 1 0 Putative lysophospholipase Pkinase PF00069.20 EEQ30285.1 - 8e-36 123.5 0.0 1.3e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30285.1 - 5.8e-23 81.2 0.0 8.3e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ30285.1 - 0.0032 16.4 0.0 0.011 14.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEQ30285.1 - 0.0048 15.9 0.1 0.008 15.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ30285.1 - 0.0086 15.8 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEQ30285.1 - 0.02 14.2 0.0 0.058 12.7 0.0 1.8 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 5_nucleotid PF05761.9 EEQ30285.1 - 0.068 11.6 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family F-box-like_2 PF13013.1 EEQ30286.1 - 0.0017 18.0 0.7 0.0046 16.6 0.5 1.9 1 1 0 1 1 1 1 F-box-like domain Mt_ATP-synt_D PF05873.7 EEQ30288.1 - 4.3e-18 65.4 1.8 5.2e-18 65.1 1.3 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SM_b PF10741.4 EEQ30288.1 - 0.017 14.7 0.9 0.06 12.9 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b EzrA PF06160.7 EEQ30288.1 - 0.024 12.8 2.2 0.044 11.9 1.5 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Tropomyosin PF00261.15 EEQ30288.1 - 0.051 12.6 2.4 0.32 10.0 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin FlaC_arch PF05377.6 EEQ30288.1 - 0.12 12.2 1.0 31 4.5 0.5 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 EEQ30288.1 - 0.94 9.3 6.8 3.4 7.4 1.3 2.5 1 1 0 2 2 2 0 Tropomyosin like NAC PF01849.13 EEQ30289.1 - 9.6e-24 82.6 0.0 9.1e-23 79.5 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EEQ30289.1 - 0.00029 20.5 0.5 0.00057 19.6 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Myc_N PF01056.13 EEQ30289.1 - 4.8 6.2 8.3 1.8 7.6 3.2 1.8 2 0 0 2 2 2 0 Myc amino-terminal region Ribosomal_L14e PF01929.12 EEQ30290.1 - 4.5e-26 91.0 2.7 6.3e-26 90.5 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EEQ30290.1 - 3.7e-07 29.5 0.3 7.1e-07 28.7 0.2 1.5 1 0 0 1 1 1 1 KOW motif MFS_1 PF07690.11 EEQ30292.1 - 2.8e-33 115.1 32.1 5.9e-22 77.8 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ30292.1 - 3.7e-13 48.8 11.7 8.8e-13 47.6 1.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EEQ30292.1 - 1.2e-12 46.9 0.0 4.1e-07 28.7 0.3 3.6 1 1 3 4 4 4 4 MFS/sugar transport protein Folate_carrier PF01770.13 EEQ30292.1 - 1.6e-05 23.6 0.0 2.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier MFS_1_like PF12832.2 EEQ30292.1 - 0.00013 21.6 4.5 0.03 14.1 0.1 3.2 2 1 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.8 EEQ30292.1 - 0.023 12.8 6.2 0.022 12.8 0.3 3.0 2 2 0 4 4 4 0 Transmembrane secretion effector SRP-alpha_N PF04086.8 EEQ30293.1 - 1.6e-68 231.1 0.0 2.3e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EEQ30293.1 - 8.8e-51 172.1 0.0 1.5e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EEQ30293.1 - 5.1e-07 29.7 0.1 2.8e-06 27.3 0.0 2.4 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EEQ30293.1 - 6.2e-07 28.4 0.0 1.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EEQ30293.1 - 1e-06 28.2 0.1 2.6e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EEQ30293.1 - 0.0002 21.4 0.1 0.0039 17.2 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 EEQ30293.1 - 0.0028 17.2 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EEQ30293.1 - 0.0042 16.7 0.1 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GSK-3_bind PF05350.7 EEQ30293.1 - 0.019 14.4 2.1 0.043 13.2 1.5 1.5 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding MMR_HSR1 PF01926.18 EEQ30293.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Fer4_NifH PF00142.13 EEQ30293.1 - 0.044 12.9 0.0 0.089 11.9 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YIF1 PF03878.10 EEQ30295.1 - 8.5e-72 241.1 4.3 1.1e-71 240.8 3.0 1.1 1 0 0 1 1 1 1 YIF1 BAF1_ABF1 PF04684.8 EEQ30295.1 - 9.7 4.9 6.4 17 4.1 4.4 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Catalase PF00199.14 EEQ30296.1 - 3.3e-165 549.4 0.8 4.1e-165 549.1 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEQ30296.1 - 1.6e-16 59.8 0.0 3.1e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EEQ30296.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family RabGAP-TBC PF00566.13 EEQ30298.1 - 6.2e-34 117.3 4.0 1.1e-33 116.5 2.8 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EEQ30298.1 - 1e-10 41.2 0.0 9.2e-08 31.6 0.0 3.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3548) DUF2360 PF10152.4 EEQ30298.1 - 0.2 11.9 6.6 0.056 13.7 1.7 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) GAS2 PF02187.12 EEQ30299.1 - 0.00018 21.2 0.1 0.00037 20.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.7 EEQ30300.1 - 1.4e-91 306.4 0.0 2.6e-72 243.2 0.0 2.0 1 1 1 2 2 2 2 Hus1-like protein Sec16_C PF12931.2 EEQ30301.1 - 1.1e-107 360.0 0.0 1.6e-107 359.5 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 EEQ30301.1 - 1.2e-53 182.6 17.3 1.2e-53 182.6 12.0 4.0 4 0 0 4 4 4 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 EEQ30301.1 - 6.8e-31 106.6 0.0 1.7e-30 105.3 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region TPR_19 PF14559.1 EEQ30301.1 - 0.64 10.4 3.8 13 6.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 EEQ30302.1 - 3.9e-17 62.0 0.0 9.3e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ30302.1 - 2.5e-13 50.9 0.0 2.4e-12 47.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ30302.1 - 4.3e-11 43.3 0.0 1e-10 42.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ30302.1 - 2.2e-08 33.9 0.1 1.5e-07 31.2 0.0 2.5 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ30302.1 - 0.0074 15.9 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mso1_Sec1_bdg PF14475.1 EEQ30303.1 - 3.3e-08 32.7 0.0 6.6e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 EEQ30304.1 - 4.7e-32 110.8 0.6 8.1e-32 110.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EEQ30304.1 - 9.9e-24 83.3 14.6 9.9e-24 83.3 10.1 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 EEQ30304.1 - 1.7e-05 24.1 12.8 2.2e-05 23.7 8.9 1.2 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.8 EEQ30304.1 - 0.02 14.7 9.6 0.026 14.4 6.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EEQ30304.1 - 0.025 12.5 28.1 0.034 12.0 19.5 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.8 EEQ30304.1 - 0.055 13.4 7.6 0.083 12.8 5.3 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Ribosomal_L24e PF01246.15 EEQ30304.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L24e CENP-T PF15511.1 EEQ30304.1 - 0.38 9.9 15.2 0.51 9.5 10.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIIF_alpha PF05793.7 EEQ30304.1 - 0.41 8.9 23.4 0.5 8.6 16.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C2H2 PF00096.21 EEQ30305.1 - 0.0012 19.0 34.9 0.096 13.0 2.3 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ30305.1 - 0.11 12.9 1.4 0.11 12.9 1.0 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EEQ30305.1 - 5.6 7.1 23.0 1.9 8.6 4.3 4.2 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) ECH PF00378.15 EEQ30306.1 - 3.7e-25 88.4 0.0 4.5e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family D123 PF07065.9 EEQ30307.1 - 1.7e-91 306.4 0.0 8.9e-91 304.0 0.0 1.8 1 1 1 2 2 2 1 D123 Vps51 PF08700.6 EEQ30308.1 - 3.3e-13 49.2 2.3 9.9e-13 47.7 0.0 3.0 3 0 0 3 3 3 1 Vps51/Vps67 DUF1640 PF07798.6 EEQ30308.1 - 1.5e-10 41.3 8.4 2.7e-10 40.5 2.5 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) ALMT PF11744.3 EEQ30308.1 - 8.9 4.8 10.0 0.3 9.7 2.1 2.0 3 0 0 3 3 3 0 Aluminium activated malate transporter HEAT_2 PF13646.1 EEQ30309.1 - 1.3e-10 41.4 0.8 0.0071 16.5 0.0 7.1 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 EEQ30309.1 - 1.5e-06 27.7 12.7 1.1 9.4 0.0 10.1 12 0 0 12 12 12 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EEQ30309.1 - 0.0039 17.5 0.0 0.085 13.2 0.0 3.3 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Transcrip_reg PF01709.15 EEQ30310.1 - 2.7e-63 213.2 0.0 3.1e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF416 PF04222.7 EEQ30310.1 - 0.13 11.4 0.1 0.41 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF416) CENP-I PF07778.6 EEQ30311.1 - 3.4e-91 305.9 0.5 5e-91 305.4 0.4 1.2 1 0 0 1 1 1 1 Mis6 EF-hand_2 PF09068.6 EEQ30311.1 - 0.1 12.6 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 EF hand DUF4360 PF14273.1 EEQ30312.1 - 1.8e-63 213.5 1.2 2.1e-63 213.3 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CLPTM1 PF05602.7 EEQ30313.1 - 1.8e-141 471.8 0.1 2.4e-141 471.4 0.1 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) MtN3_slv PF03083.11 EEQ30313.1 - 1.2 9.0 6.7 0.091 12.6 0.3 2.3 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange 2TM PF13239.1 EEQ30313.1 - 4.6 7.3 9.4 0.74 9.9 1.7 3.1 2 1 1 3 3 3 0 2TM domain adh_short PF00106.20 EEQ30314.1 - 2.9e-07 30.5 0.0 4.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ30314.1 - 2.6e-06 27.4 0.0 4.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ASXH PF13919.1 EEQ30315.1 - 1.4e-41 141.5 0.1 4e-41 140.0 0.1 1.8 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.1 EEQ30316.1 - 8.5e-29 98.9 1.4 1.5e-28 98.1 1.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EEQ30316.1 - 5.5e-14 51.5 1.7 7.5e-14 51.1 0.0 1.9 2 0 0 2 2 2 1 Synaptobrevin DUF3510 PF12022.3 EEQ30316.1 - 0.036 14.1 2.5 0.27 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DUF1664 PF07889.7 EEQ30316.1 - 0.098 12.4 1.8 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PilJ PF13675.1 EEQ30316.1 - 0.28 11.5 2.6 3.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term EMP24_GP25L PF01105.19 EEQ30316.1 - 5.7 6.6 7.2 4 7.1 0.5 2.2 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Elong_Iki1 PF10483.4 EEQ30317.1 - 1.1e-85 287.4 0.0 1.3e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF1777 PF08648.7 EEQ30318.1 - 1.8e-24 86.4 71.2 1e-23 84.0 45.1 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) DAO PF01266.19 EEQ30319.1 - 2.4e-61 207.6 0.5 2.9e-61 207.3 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ30319.1 - 1.1e-07 31.7 0.6 4e-07 29.9 0.1 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEQ30319.1 - 0.001 17.8 0.1 0.07 11.7 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EEQ30319.1 - 0.0017 17.3 0.1 0.005 15.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EEQ30319.1 - 0.0025 18.1 0.2 0.014 15.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ30319.1 - 0.0035 16.4 0.1 0.0068 15.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EEQ30319.1 - 0.0074 16.1 0.3 2.3 8.0 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 EEQ30319.1 - 0.022 13.1 0.1 0.032 12.6 0.1 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_9 PF13454.1 EEQ30319.1 - 0.024 14.3 0.3 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEQ30319.1 - 0.052 13.6 0.0 16 5.4 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEQ30319.1 - 0.052 12.3 0.2 3.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_63 PF03200.11 EEQ30320.1 - 5.5e-246 818.3 0.0 4.3e-245 815.3 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EEQ30320.1 - 0.0056 15.3 0.5 0.0099 14.5 0.3 1.3 1 0 0 1 1 1 1 Trehalase MMtag PF10159.4 EEQ30321.1 - 1.8e-32 111.2 3.2 2.7e-32 110.6 2.2 1.3 1 0 0 1 1 1 1 Kinase phosphorylation protein CRT10 PF08728.5 EEQ30322.1 - 2.8e-13 48.7 0.0 5.2e-08 31.3 0.0 2.2 2 0 0 2 2 2 2 CRT10 DUF3402 PF11882.3 EEQ30323.1 - 3.6e-141 470.9 0.0 4.7e-141 470.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EEQ30323.1 - 1.7e-80 270.0 0.0 2.3e-80 269.5 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein RWD PF05773.17 EEQ30324.1 - 2.6e-21 75.6 0.1 5.1e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EEQ30324.1 - 7.2e-18 64.2 39.6 6.4e-15 54.7 1.7 4.0 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EEQ30324.1 - 0.0026 17.5 10.8 0.0026 17.5 7.5 3.6 2 1 1 3 3 3 2 Ring finger domain PAP2 PF01569.16 EEQ30325.1 - 3.7e-18 65.4 0.8 6.5e-18 64.6 0.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 EEQ30325.1 - 0.031 13.9 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family Ldh_2 PF02615.9 EEQ30326.1 - 7.7e-104 347.0 0.0 8.8e-104 346.8 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF2346 PF09803.4 EEQ30327.1 - 4.4e-06 26.4 0.0 6.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) DUF3317 PF11779.3 EEQ30328.1 - 2.9e-22 77.8 5.7 3.6e-22 77.5 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Tenui_PVC2 PF06656.6 EEQ30328.1 - 0.12 10.1 0.4 0.12 10.0 0.3 1.0 1 0 0 1 1 1 0 Tenuivirus PVC2 protein RF-1 PF00472.15 EEQ30329.1 - 3.8e-19 68.5 11.0 1.7e-13 50.3 7.4 2.2 2 0 0 2 2 2 2 RF-1 domain Selenoprotein_S PF06936.6 EEQ30329.1 - 0.84 9.1 7.1 1.6 8.2 5.0 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) DOR PF14839.1 EEQ30329.1 - 3 7.5 7.7 5.9 6.5 5.3 1.4 1 0 0 1 1 1 0 DOR family CAS_CSE1 PF03378.10 EEQ30330.1 - 4.1e-158 526.2 0.0 1.1e-157 524.8 0.0 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EEQ30330.1 - 4.5e-154 512.4 1.7 7e-154 511.8 1.2 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EEQ30330.1 - 1.2e-15 57.1 0.1 5.2e-15 55.1 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EEQ30330.1 - 0.011 15.7 1.6 1 9.2 0.0 4.0 3 1 0 3 3 3 0 Exportin 1-like protein APH PF01636.18 EEQ30332.1 - 7.7e-05 22.5 0.3 0.0003 20.6 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ30332.1 - 0.032 13.8 0.2 0.045 13.3 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3642 PF12182.3 EEQ30332.1 - 0.099 13.0 2.9 0.16 12.3 2.0 1.3 1 0 0 1 1 1 0 Bacterial lipoprotein DUF3384 PF11864.3 EEQ30333.1 - 1.3e-61 208.5 0.0 3e-56 190.8 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EEQ30333.1 - 1.8e-49 167.7 0.0 2.8e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EEQ30333.1 - 4.5e-28 98.3 3.4 4.4e-26 91.7 0.0 3.1 3 0 0 3 3 3 2 Tuberin PUF PF00806.14 EEQ30334.1 - 3e-58 190.1 5.8 1.6e-07 30.4 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat PepSY_TM_2 PF13703.1 EEQ30336.1 - 0.015 15.4 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix Herpes_gE PF02480.11 EEQ30336.1 - 0.015 13.6 0.0 0.018 13.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PgaD PF13994.1 EEQ30336.1 - 0.042 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein Phosphodiest PF01663.17 EEQ30337.1 - 2.4e-16 60.0 0.7 4.7e-16 59.0 0.5 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EEQ30337.1 - 1.9e-05 24.2 1.3 3.2e-05 23.4 0.9 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EEQ30337.1 - 0.00029 20.1 0.1 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 Sulfatase cwf21 PF08312.7 EEQ30338.1 - 4e-17 61.7 19.3 4e-17 61.7 13.4 2.1 2 1 0 2 2 2 1 cwf21 domain Staphylokinase PF02821.11 EEQ30338.1 - 0.066 13.0 3.0 0.048 13.4 0.7 1.7 2 0 0 2 2 2 0 Staphylokinase/Streptokinase family DUF4011 PF13195.1 EEQ30338.1 - 2.7 7.9 11.8 0.91 9.5 6.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) RRN3 PF05327.6 EEQ30338.1 - 2.8 5.9 4.5 3.8 5.5 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3650 PF12368.3 EEQ30338.1 - 3.1 7.3 8.1 0.13 11.7 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) HA2 PF04408.18 EEQ30339.1 - 7.9e-20 70.7 0.1 2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ30339.1 - 3.7e-15 55.5 0.0 1.1e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EEQ30339.1 - 8e-11 41.7 0.0 2.1e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EEQ30339.1 - 5.7e-09 35.6 0.0 4e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EEQ30339.1 - 3.1e-05 23.8 0.0 0.28 11.0 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEQ30339.1 - 0.0068 16.5 0.0 0.028 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ30339.1 - 0.038 13.4 0.0 0.091 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EEQ30339.1 - 0.058 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EEQ30339.1 - 0.3 11.3 0.0 0.3 11.3 0.0 3.5 4 0 0 4 4 4 0 AAA domain DUF2372 PF10178.4 EEQ30340.1 - 0.0003 20.8 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) Cohesin_load PF10345.4 EEQ30342.1 - 3e-161 537.6 11.5 3.7e-161 537.4 8.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor Lactamase_B_4 PF13691.1 EEQ30342.1 - 0.075 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 tRNase Z endonuclease Histone PF00125.19 EEQ30343.1 - 2.8e-28 97.8 0.1 4.2e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEQ30343.1 - 0.00028 20.9 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEQ30343.1 - 0.0085 16.1 0.4 0.017 15.1 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EEQ30343.1 - 0.019 14.2 0.9 0.031 13.5 0.6 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DER1 PF04511.10 EEQ30344.1 - 2.4e-47 161.0 4.0 2.8e-47 160.8 2.8 1.0 1 0 0 1 1 1 1 Der1-like family EMP70 PF02990.11 EEQ30345.1 - 8.1e-148 493.1 0.2 2.7e-147 491.3 0.1 1.8 1 1 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.18 EEQ30346.1 - 1.7e-16 59.3 0.0 3.1e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEQ30346.1 - 3.6e-09 36.2 0.0 8e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EEQ30346.1 - 3.4e-06 26.6 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEQ30346.1 - 6.9e-05 22.9 0.1 0.00018 21.6 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EEQ30346.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CPSF_A PF03178.10 EEQ30347.1 - 3.9e-104 348.1 0.0 4.2e-102 341.5 0.0 3.0 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EEQ30347.1 - 8e-68 228.8 0.0 1.2e-67 228.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 EEQ30347.1 - 0.034 13.7 0.1 1.1 8.8 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.27 EEQ30347.1 - 0.26 11.2 1.0 0.88 9.5 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat PRESAN PF09687.5 EEQ30348.1 - 0.023 14.7 0.4 0.051 13.6 0.3 1.5 1 0 0 1 1 1 0 Plasmodium RESA N-terminal CN_hydrolase PF00795.17 EEQ30349.1 - 5.9e-22 77.9 0.0 7.9e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BP28CT PF08146.7 EEQ30350.1 - 2.2e-44 150.8 1.2 1.1e-43 148.5 0.8 2.4 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EEQ30350.1 - 7.5e-28 96.9 2.6 7.5e-28 96.9 1.8 6.9 8 0 0 8 8 8 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EEQ30350.1 - 1.5e-05 25.1 5.9 0.87 9.9 0.0 5.4 5 0 0 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EEQ30350.1 - 0.19 12.2 13.4 1 9.9 0.2 5.7 6 0 0 6 6 6 0 HEAT-like repeat HEAT PF02985.17 EEQ30350.1 - 0.2 11.8 9.7 0.28 11.3 0.0 5.3 7 0 0 7 7 7 0 HEAT repeat NRDE-2 PF08424.5 EEQ30351.1 - 1.9e-90 303.0 0.1 3.8e-88 295.4 0.0 3.1 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 EEQ30351.1 - 0.0023 18.5 0.1 1.1 10.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.9 EEQ30351.1 - 0.061 13.0 0.0 0.061 13.0 0.0 2.4 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) UDG PF03167.14 EEQ30352.1 - 4.4e-19 68.4 0.0 6.4e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily 7TMR-DISM_7TM PF07695.6 EEQ30353.1 - 0.42 10.2 8.4 1 8.9 5.8 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling NAD_binding_6 PF08030.7 EEQ30356.1 - 1.1e-23 83.8 0.0 2e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ30356.1 - 6.2e-23 80.6 0.0 1.3e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EEQ30356.1 - 8e-18 64.7 10.4 1.7e-17 63.6 7.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EEQ30356.1 - 5.8e-05 23.1 0.0 0.00015 21.8 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEQ30356.1 - 0.01 16.3 0.0 3.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SBDS PF01172.13 EEQ30357.1 - 1.2e-28 98.6 0.2 1.5e-28 98.4 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EEQ30357.1 - 0.016 14.9 0.1 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Phage XkdN-like protein NB-ARC PF00931.17 EEQ30357.1 - 0.074 11.9 0.1 0.11 11.3 0.1 1.3 1 1 0 1 1 1 0 NB-ARC domain DUF3340 PF11818.3 EEQ30357.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) RhoGEF PF00621.15 EEQ30358.1 - 5.1e-20 72.0 0.1 6.8e-18 65.1 0.0 2.5 1 1 1 2 2 2 2 RhoGEF domain GRASP55_65 PF04495.9 EEQ30359.1 - 5.6e-07 29.6 0.0 9.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EEQ30359.1 - 8.1e-07 28.8 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EEQ30359.1 - 1.3e-05 25.2 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 EEQ30360.1 - 8.4e-50 168.3 0.0 1e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ30360.1 - 4.2e-16 59.5 0.0 8.4e-16 58.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEQ30360.1 - 2.5e-11 43.1 0.0 3.8e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EEQ30360.1 - 0.00023 21.3 0.1 0.0011 19.1 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EEQ30360.1 - 0.00037 19.6 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EEQ30360.1 - 0.0067 15.1 2.0 1.2 7.7 0.1 2.9 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.7 EEQ30360.1 - 0.029 13.6 0.1 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EEQ30360.1 - 0.045 13.9 0.1 0.15 12.2 0.0 1.8 1 1 0 2 2 2 0 AAA domain SRPRB PF09439.5 EEQ30360.1 - 0.072 12.3 0.0 0.12 11.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EEQ30360.1 - 0.08 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EEQ30361.1 - 2.3e-69 233.4 0.7 3.3e-69 232.9 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ30361.1 - 1.8e-10 40.5 0.0 4.6e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EEQ30361.1 - 1.9e-09 37.0 3.2 3.5e-09 36.1 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ30361.1 - 2e-07 30.8 4.9 4.9e-07 29.6 3.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ30361.1 - 4.9e-06 26.2 3.8 9.8e-06 25.3 2.6 1.5 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 EEQ30361.1 - 1.5e-05 24.5 0.0 4.3e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EEQ30361.1 - 1.7e-05 24.3 3.5 4.4e-05 23.0 2.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ30361.1 - 0.00035 20.2 3.6 0.00079 19.0 2.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EEQ30361.1 - 0.0013 18.2 2.7 0.0037 16.8 1.9 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EEQ30361.1 - 0.0015 18.2 1.1 0.0034 17.0 0.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEQ30361.1 - 0.0063 16.3 5.5 0.014 15.2 3.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Fes1 PF08609.5 EEQ30361.1 - 0.11 12.9 0.6 2.1 8.9 0.1 2.6 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 F-box-like PF12937.2 EEQ30362.1 - 0.01 15.5 0.0 5.2 6.8 0.0 2.5 2 0 0 2 2 2 0 F-box-like SCP2 PF02036.12 EEQ30363.1 - 8.6e-24 83.7 0.1 1.1e-23 83.4 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EEQ30363.1 - 3.3e-05 23.8 0.0 4.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Ran_BP1 PF00638.13 EEQ30364.1 - 8.1e-13 48.4 0.0 1.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EEQ30364.1 - 1.8e-05 24.9 32.2 1.8e-05 24.9 22.3 10.0 3 2 6 9 9 9 5 Nucleoporin FG repeat region Ribosomal_L31e PF01198.14 EEQ30365.1 - 1.3e-38 130.5 1.5 1.6e-38 130.2 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.13 EEQ30365.1 - 0.037 13.3 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel CN_hydrolase PF00795.17 EEQ30366.1 - 2.8e-32 111.5 0.0 4.4e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 EEQ30367.1 - 4.3e-10 38.9 2.9 7.2e-10 38.1 2.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ30367.1 - 3e-06 27.0 8.0 5.5e-06 26.1 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EEQ30368.1 - 9.6e-25 87.3 0.0 3.2e-18 65.8 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EEQ30368.1 - 7.1e-08 31.5 1.6 2e-05 23.4 0.1 2.4 1 1 1 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EEQ30368.1 - 5.7e-05 22.2 0.0 9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EEQ30368.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ30368.1 - 0.0012 17.8 0.2 0.22 10.3 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ30368.1 - 0.0032 17.4 0.5 0.0095 15.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEQ30368.1 - 0.0053 17.1 0.0 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ30368.1 - 0.06 13.2 0.6 0.13 12.1 0.4 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EEQ30368.1 - 0.1 12.1 0.1 0.28 10.7 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thioesterase PF00975.15 EEQ30369.1 - 6.2e-21 75.6 0.3 1.1e-20 74.8 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EEQ30369.1 - 1.5e-08 34.8 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ30369.1 - 1.9e-06 27.6 0.0 5e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ30369.1 - 0.00016 21.3 0.0 0.00031 20.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EEQ30369.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Pyr_redox PF00070.22 EEQ30369.1 - 0.11 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.8 EEQ30369.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.3 EEQ30369.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Asp PF00026.18 EEQ30370.1 - 3.4e-10 39.6 0.1 7.1e-09 35.3 0.0 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEQ30370.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Crl PF07417.7 EEQ30370.1 - 0.078 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Crl p450 PF00067.17 EEQ30371.1 - 8.2e-50 169.6 0.0 1.4e-49 168.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EEQ30372.1 - 1.7e-84 283.6 0.0 3.1e-84 282.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EEQ30372.1 - 9e-74 248.1 0.0 1.9e-73 247.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ30372.1 - 3.9e-64 216.9 0.0 6.7e-64 216.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EEQ30372.1 - 9.4e-59 198.1 0.0 1.3e-57 194.3 0.0 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EEQ30372.1 - 4.9e-55 186.7 0.0 8e-55 186.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EEQ30372.1 - 9.9e-53 178.9 0.0 1.6e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EEQ30372.1 - 1.1e-45 155.4 0.5 4.1e-45 153.7 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEQ30372.1 - 9.2e-40 135.2 1.0 4.3e-39 133.0 0.2 2.5 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EEQ30372.1 - 2.4e-36 124.9 0.0 8.2e-36 123.1 0.0 2.0 1 0 0 1 1 1 1 Male sterility protein ADH_zinc_N PF00107.21 EEQ30372.1 - 2e-20 72.6 0.0 6.4e-20 71.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EEQ30372.1 - 3.5e-20 72.0 0.1 1.7e-09 37.7 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 EEQ30372.1 - 4.1e-12 47.0 0.0 3.8e-10 40.7 0.0 4.0 5 0 0 5 5 4 1 Zinc-binding dehydrogenase HxxPF_rpt PF13745.1 EEQ30372.1 - 8e-11 42.1 0.0 2.7e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain Thiolase_N PF00108.18 EEQ30372.1 - 0.0068 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GP120 PF00516.13 EEQ30372.1 - 7.3 4.6 0.0 13 3.9 0.0 1.2 1 0 0 1 1 1 0 Envelope glycoprotein GP120 ATG2_CAD PF13329.1 EEQ30376.1 - 3e-48 163.3 0.2 8.4e-48 161.9 0.1 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EEQ30376.1 - 1.4e-25 89.3 0.1 3.4e-25 88.0 0.1 1.8 1 0 0 1 1 1 1 ATG C terminal domain A_deaminase PF00962.17 EEQ30377.1 - 1.2e-37 129.5 0.0 1.2e-36 126.3 0.0 2.0 2 0 0 2 2 2 1 Adenosine/AMP deaminase Ank_2 PF12796.2 EEQ30380.1 - 3.2e-39 133.1 8.1 1.9e-14 53.7 0.1 4.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ30380.1 - 5.7e-27 92.1 9.2 2.3e-06 27.1 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EEQ30380.1 - 9.9e-22 76.4 2.6 7.2e-06 26.0 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ30380.1 - 3.7e-21 75.0 4.0 2.2e-06 28.0 0.0 5.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ30380.1 - 5e-20 69.5 8.8 0.00014 21.7 0.0 7.5 8 0 0 8 8 8 3 Ankyrin repeat NACHT PF05729.7 EEQ30380.1 - 1.4e-09 37.7 0.2 5.8e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EEQ30380.1 - 1.5e-07 31.5 0.8 3.4e-06 27.1 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ30380.1 - 0.0019 18.3 0.1 0.016 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEQ30380.1 - 0.045 13.9 0.1 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase APH PF01636.18 EEQ30381.1 - 1.8e-10 41.0 0.0 4.8e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEQ30381.1 - 0.0096 14.9 0.4 1.7 7.5 0.0 2.5 3 0 0 3 3 3 2 Fructosamine kinase DUF1679 PF07914.6 EEQ30381.1 - 0.047 12.3 0.3 0.12 11.0 0.0 1.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) Ribosomal_S17 PF00366.15 EEQ30383.1 - 0.00011 22.1 0.7 0.00018 21.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 AAA PF00004.24 EEQ30384.1 - 8.6e-37 126.2 0.0 1.4e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EEQ30384.1 - 3.8e-09 36.3 0.1 1.9e-06 27.6 0.0 3.1 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EEQ30384.1 - 8.4e-06 25.9 0.6 9.9e-05 22.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EEQ30384.1 - 7.6e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EEQ30384.1 - 9.3e-05 21.5 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEQ30384.1 - 0.00048 20.1 1.5 0.0051 16.8 0.2 2.7 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EEQ30384.1 - 0.0016 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EEQ30384.1 - 0.0021 17.7 0.0 0.0068 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EEQ30384.1 - 0.0031 16.2 0.0 0.0057 15.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EEQ30384.1 - 0.0038 16.4 0.1 0.0077 15.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EEQ30384.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ30384.1 - 0.0069 16.1 0.2 0.028 14.1 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_25 PF13481.1 EEQ30384.1 - 0.013 14.8 0.3 0.22 10.9 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EEQ30384.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EEQ30384.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EEQ30384.1 - 0.033 14.1 0.4 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EEQ30384.1 - 0.035 14.9 1.1 0.08 13.7 0.0 2.3 3 1 0 3 3 1 0 AAA domain NACHT PF05729.7 EEQ30384.1 - 0.075 12.6 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EEQ30384.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEQ30384.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EEQ30384.1 - 0.16 11.1 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein MMR_HSR1 PF01926.18 EEQ30385.1 - 8.6e-05 22.4 0.1 0.00073 19.4 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Telomere_Sde2 PF13019.1 EEQ30386.1 - 2e-64 216.1 0.1 2e-64 216.1 0.0 1.4 2 0 0 2 2 2 1 Telomere stability and silencing S10_plectin PF03501.10 EEQ30387.1 - 7.6e-40 134.6 0.2 9.9e-40 134.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M20 PF01546.23 EEQ30388.1 - 2.7e-21 75.9 0.2 3.8e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEQ30388.1 - 1.2e-06 28.2 0.0 3.2e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EEQ30388.1 - 0.0017 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 HIT PF01230.18 EEQ30389.1 - 1.4e-17 63.9 0.0 1.9e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EEQ30389.1 - 3.2e-09 37.0 0.0 3.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CRAL_TRIO PF00650.15 EEQ30390.1 - 5.9e-41 139.6 0.0 1.8e-40 138.0 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEQ30390.1 - 6.1e-15 55.1 1.2 1.1e-14 54.2 0.1 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEQ30390.1 - 3.1e-10 40.1 0.0 6.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.5 EEQ30391.1 - 1.6e-29 101.4 1.7 2.3e-29 100.9 1.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF2265 PF10023.4 EEQ30391.1 - 0.061 12.4 0.3 0.081 12.0 0.2 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) CytochromB561_N PF09786.4 EEQ30391.1 - 0.67 8.3 8.0 0.84 8.0 5.6 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal CENP-B_dimeris PF09026.5 EEQ30392.1 - 0.00015 21.9 2.0 0.00017 21.7 1.4 1.1 1 0 0 1 1 1 1 Centromere protein B dimerisation domain FAM176 PF14851.1 EEQ30392.1 - 0.018 14.7 0.4 0.021 14.4 0.3 1.1 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.8 EEQ30392.1 - 0.049 11.4 10.2 0.064 11.0 7.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.7 EEQ30392.1 - 0.052 12.7 3.8 0.06 12.5 2.6 1.1 1 0 0 1 1 1 0 NOA36 protein Nro1 PF12753.2 EEQ30392.1 - 0.052 12.4 1.9 0.064 12.2 1.3 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF4484 PF14831.1 EEQ30392.1 - 0.13 12.3 2.0 0.16 12.0 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Nucleoplasmin PF03066.10 EEQ30392.1 - 0.15 11.6 6.7 0.2 11.1 4.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EEQ30392.1 - 0.27 11.0 1.6 0.35 10.6 1.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 EEQ30392.1 - 0.71 8.5 7.0 0.82 8.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 EEQ30392.1 - 0.79 10.0 4.9 1.2 9.5 3.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mak16 PF04874.9 EEQ30392.1 - 3 7.9 9.9 4.5 7.4 6.7 1.4 1 1 0 1 1 1 0 Mak16 protein C-terminal region UCH PF00443.24 EEQ30393.1 - 3.7e-61 206.5 0.0 6.8e-61 205.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ30393.1 - 1.6e-24 86.8 1.8 2.2e-23 83.1 1.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEQ30393.1 - 5.9e-05 23.1 2.2 8.4e-05 22.6 0.2 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DUF3435 PF11917.3 EEQ30394.1 - 4e-08 32.3 0.3 5.1e-08 32.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) adh_short PF00106.20 EEQ30395.1 - 9.2e-18 64.7 0.0 1.5e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ30395.1 - 1.7e-06 27.7 0.0 2.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Rhomboid PF01694.17 EEQ30396.1 - 2.8e-09 37.1 8.0 2.8e-09 37.1 5.6 1.8 2 0 0 2 2 2 1 Rhomboid family Ytp1 PF10355.4 EEQ30397.1 - 5.2e-112 373.4 8.3 5.2e-112 373.4 5.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EEQ30397.1 - 1.3e-30 105.0 6.0 1.3e-30 105.0 4.2 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) Metallophos PF00149.23 EEQ30401.1 - 0.02 14.2 2.5 0.11 11.9 1.7 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase RTA1 PF04479.8 EEQ30402.1 - 8.6e-47 159.5 1.3 1.4e-46 158.7 0.9 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF3040 PF11239.3 EEQ30402.1 - 9.1 6.4 8.1 3.9 7.5 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Gaa1 PF04114.9 EEQ30404.1 - 4.3e-98 329.2 6.5 5.5e-98 328.8 4.5 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 EEQ30405.1 - 1.3e-09 38.2 0.1 3.1e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain Methyltransf_31 PF13847.1 EEQ30406.1 - 1.1e-15 57.4 0.0 1.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ30406.1 - 4.6e-13 49.1 0.0 5.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ30406.1 - 1.1e-12 48.2 0.0 2.2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ30406.1 - 3.6e-12 46.6 0.0 7.3e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ30406.1 - 1.5e-11 44.8 0.0 2.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ30406.1 - 6.6e-09 35.2 0.0 1.6e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EEQ30406.1 - 1.3e-08 35.0 0.0 2.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ30406.1 - 6.9e-05 22.8 0.0 0.00017 21.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEQ30406.1 - 0.00035 20.2 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ30406.1 - 0.0019 17.6 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 EEQ30406.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.14 EEQ30406.1 - 0.025 14.1 0.0 0.045 13.2 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EEQ30406.1 - 0.032 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GMC_oxred_N PF00732.14 EEQ30407.1 - 6.1e-60 202.8 0.0 8.4e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ30407.1 - 1.9e-37 128.7 0.0 2.9e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EEQ30407.1 - 7.8e-07 28.3 0.0 6.2e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ30407.1 - 0.00019 21.3 0.0 0.00081 19.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEQ30407.1 - 0.00032 19.6 0.0 0.028 13.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EEQ30407.1 - 0.00068 18.6 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EEQ30407.1 - 0.004 17.5 0.1 3 8.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ30407.1 - 0.03 13.4 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EEQ30407.1 - 0.083 12.7 0.0 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ30407.1 - 0.18 10.2 0.0 0.32 9.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_10 PF13460.1 EEQ30410.1 - 4.8e-17 62.5 0.0 7.8e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ30410.1 - 5.8e-15 55.3 0.0 1.4e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ30410.1 - 5.2e-12 45.0 0.0 8.5e-12 44.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EEQ30410.1 - 1.7e-11 43.8 0.0 3.4e-11 42.8 0.0 1.4 1 1 1 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 EEQ30410.1 - 4.4e-06 25.8 0.2 0.00054 18.9 0.1 2.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EEQ30410.1 - 1.1e-05 24.5 0.0 0.029 13.2 0.0 2.4 2 1 0 2 2 2 2 RmlD substrate binding domain Saccharop_dh PF03435.13 EEQ30410.1 - 0.0023 16.9 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EEQ30410.1 - 0.006 16.5 0.0 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase DDE_Tnp_1_3 PF13612.1 EEQ30410.1 - 0.0078 15.9 0.0 0.038 13.7 0.0 1.9 2 0 0 2 2 2 1 Transposase DDE domain HIM1 PF08732.5 EEQ30410.1 - 0.0084 14.6 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 HIM1 KR PF08659.5 EEQ30410.1 - 0.06 13.0 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 KR domain HEM4 PF02602.10 EEQ30411.1 - 1.2e-30 106.5 0.0 1.3e-29 103.0 0.0 2.0 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.20 EEQ30412.1 - 3.7e-73 245.8 0.0 4.4e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30412.1 - 1.1e-31 109.9 0.0 1.4e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ30412.1 - 0.00041 19.4 0.0 0.0015 17.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEQ30412.1 - 0.0038 16.3 0.4 0.0066 15.5 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ30412.1 - 0.011 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEQ30412.1 - 0.066 12.0 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF812 PF05667.6 EEQ30414.1 - 1.2 7.5 4.4 1.5 7.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Sec23_trunk PF04811.10 EEQ30415.1 - 1.2e-71 240.8 0.0 2e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEQ30415.1 - 1e-22 79.5 0.0 2.3e-21 75.1 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EEQ30415.1 - 6.9e-18 63.9 4.3 1.3e-17 63.0 3.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EEQ30415.1 - 9.9e-17 61.2 0.0 2.4e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EEQ30415.1 - 1.2e-06 28.1 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat TEX12 PF15219.1 EEQ30415.1 - 0.29 11.1 1.0 0.74 9.8 0.7 1.7 1 0 0 1 1 1 0 Testis-expressed 12 Kinesin PF00225.18 EEQ30416.1 - 4e-75 252.6 0.9 1.1e-74 251.2 0.6 1.7 1 1 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EEQ30416.1 - 0.0003 20.3 0.1 0.082 12.6 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif TPR_12 PF13424.1 EEQ30416.1 - 0.016 15.0 0.2 0.11 12.3 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH_3 PF12836.2 EEQ30416.1 - 0.045 13.6 0.0 7.2 6.6 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif TPR_11 PF13414.1 EEQ30416.1 - 0.17 11.5 0.2 0.41 10.3 0.2 1.6 1 0 0 1 1 1 0 TPR repeat MFS_1 PF07690.11 EEQ30417.1 - 2.6e-25 88.9 71.5 1.6e-20 73.1 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEQ30417.1 - 1.7e-09 36.6 17.3 1.7e-09 36.6 12.0 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein OapA_N PF08525.6 EEQ30417.1 - 0.095 12.4 2.7 0.39 10.5 1.9 2.2 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Peptidase_M43 PF05572.8 EEQ30419.1 - 6.6e-16 58.2 4.5 9.9e-13 47.9 0.8 2.2 1 1 1 2 2 2 2 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EEQ30419.1 - 1.9e-05 24.7 0.5 3.3e-05 24.0 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EEQ30419.1 - 0.00022 21.1 0.1 0.00035 20.5 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 EEQ30419.1 - 0.0045 16.3 0.6 0.0082 15.4 0.4 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.1 EEQ30419.1 - 0.013 16.0 0.4 0.022 15.2 0.3 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EEQ30419.1 - 0.014 14.3 0.4 0.016 14.0 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.19 EEQ30419.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.1 EEQ30419.1 - 0.11 11.9 0.4 0.19 11.2 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like AIM24 PF01987.12 EEQ30420.1 - 3.6e-43 147.5 0.0 4.5e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 EEQ30420.1 - 0.02 15.3 0.5 0.088 13.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) ABC_membrane PF00664.18 EEQ30421.1 - 2e-37 129.1 12.6 2.6e-37 128.7 8.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ30421.1 - 7.7e-34 116.9 0.0 1.4e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEQ30421.1 - 4.4e-07 30.1 0.0 0.0027 17.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EEQ30421.1 - 9.6e-06 24.9 0.0 0.00019 20.7 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEQ30421.1 - 0.00022 22.0 0.0 0.0005 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ30421.1 - 0.00051 20.0 0.1 0.0017 18.4 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ30421.1 - 0.00059 19.9 0.0 0.0035 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ30421.1 - 0.0015 18.4 0.0 0.027 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ30421.1 - 0.0035 16.8 0.1 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EEQ30421.1 - 0.0037 17.5 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEQ30421.1 - 0.0052 15.9 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EEQ30421.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2847 PF11009.3 EEQ30421.1 - 0.019 14.5 0.1 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AAA_28 PF13521.1 EEQ30421.1 - 0.033 14.1 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EEQ30421.1 - 0.035 12.7 0.2 0.14 10.7 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EEQ30421.1 - 0.036 13.5 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EEQ30421.1 - 0.038 14.2 0.3 0.085 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EEQ30421.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 EEQ30421.1 - 0.049 12.2 0.0 0.45 9.0 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.24 EEQ30421.1 - 0.051 13.7 0.0 0.45 10.7 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEQ30421.1 - 0.083 11.9 0.0 0.44 9.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 EEQ30421.1 - 0.091 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2013 PF09431.5 EEQ30422.1 - 1.2e-49 167.7 1.3 1.2e-49 167.7 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Glyco_hydro_17 PF00332.13 EEQ30423.1 - 2.9e-06 26.5 1.5 7.7e-06 25.1 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.16 EEQ30424.1 - 8.2e-36 123.6 0.0 1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II bcl-2I13 PF12201.3 EEQ30424.1 - 0.02 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing Baculo_PEP_N PF04512.7 EEQ30424.1 - 0.075 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Glucan_synthase PF02364.10 EEQ30425.1 - 0 1460.4 0.0 0 1460.0 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EEQ30425.1 - 2.5e-39 133.8 0.2 7e-39 132.3 0.1 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 EEQ30427.1 - 2.3e-132 440.7 8.5 2.9e-132 440.4 5.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EEQ30427.1 - 6.2e-26 90.7 2.1 2.1e-25 88.9 1.4 2.0 1 0 0 1 1 1 1 X8 domain SprT-like PF10263.4 EEQ30428.1 - 2.2e-48 163.8 0.2 3.8e-48 163.1 0.2 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M30 PF10460.4 EEQ30428.1 - 0.011 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase M30 Peptidase_MA_2 PF13485.1 EEQ30428.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily DUF4379 PF14311.1 EEQ30428.1 - 0.15 11.9 3.1 0.6 9.9 2.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Mog1 PF04603.7 EEQ30429.1 - 1.5e-16 60.6 0.0 4.9e-12 45.9 0.0 3.1 1 1 0 1 1 1 1 Ran-interacting Mog1 protein NYN PF01936.13 EEQ30430.1 - 0.00082 19.6 0.0 0.0046 17.2 0.0 2.1 1 1 0 1 1 1 1 NYN domain HSP9_HSP12 PF04119.7 EEQ30431.1 - 1.2e-25 89.3 3.3 2.2e-25 88.5 2.3 1.4 1 0 0 1 1 1 1 Heat shock protein 9/12 COG6 PF06419.6 EEQ30432.1 - 6.6e-228 757.8 2.3 7.5e-228 757.6 1.6 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 NIF3 PF01784.13 EEQ30433.1 - 7.1e-46 156.7 0.0 6e-45 153.7 0.0 1.9 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 EEQ30434.1 - 1.9e-22 78.9 0.0 2.5e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Redoxin PF08534.5 EEQ30435.1 - 3.3e-29 101.3 0.0 4.1e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EEQ30435.1 - 9.4e-08 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Response_reg PF00072.19 EEQ30436.1 - 1.2e-22 80.0 0.0 2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HSF_DNA-bind PF00447.12 EEQ30436.1 - 1.3e-11 44.5 0.1 2e-05 24.6 0.0 2.9 1 1 1 2 2 2 2 HSF-type DNA-binding UPF0506 PF11703.3 EEQ30437.1 - 0.0097 15.8 4.0 0.0097 15.8 2.8 3.3 2 1 0 2 2 2 1 UPF0506 Tme5_EGF_like PF09064.5 EEQ30437.1 - 0.012 15.1 0.2 0.012 15.1 0.1 2.4 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like W2 PF02020.13 EEQ30438.1 - 4.6e-16 58.5 3.0 4.6e-16 58.5 2.1 3.6 4 0 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EEQ30438.1 - 9.1e-11 40.7 10.8 1.2e-05 24.5 2.3 3.9 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEQ30438.1 - 2.8e-05 23.5 8.3 0.0046 16.4 2.6 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EEQ30438.1 - 0.13 10.8 0.2 0.21 10.1 0.1 1.3 1 0 0 1 1 1 0 L-fucokinase IBR PF01485.16 EEQ30439.1 - 1.9e-22 78.8 46.6 7.1e-12 45.0 3.5 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 EEQ30439.1 - 8e-06 25.7 7.9 8e-06 25.7 5.5 4.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ30439.1 - 0.00043 20.0 8.0 0.00043 20.0 5.6 3.5 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EEQ30439.1 - 0.00046 19.7 5.9 0.00046 19.7 4.1 4.4 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 EEQ30439.1 - 0.00061 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_5 PF14634.1 EEQ30439.1 - 0.0018 17.9 9.7 0.0018 17.9 6.7 3.1 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEQ30439.1 - 0.013 15.1 2.3 0.013 15.1 1.6 3.5 3 0 0 3 3 3 0 RING-type zinc-finger AceK PF06315.6 EEQ30439.1 - 0.055 11.7 0.1 0.073 11.3 0.1 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Mito_carr PF00153.22 EEQ30440.1 - 5.3e-71 234.3 6.0 1.3e-24 85.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1 PF00133.17 EEQ30441.1 - 2.4e-37 128.2 0.0 2e-26 92.1 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EEQ30441.1 - 3.4e-17 62.2 0.0 3.1e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEQ30441.1 - 1.4e-10 41.0 0.1 3.9e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EEQ30441.1 - 2.7e-07 30.0 0.0 5.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EEQ30441.1 - 0.019 13.6 0.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) L51_S25_CI-B8 PF05047.11 EEQ30442.1 - 1.1e-15 57.0 0.0 1.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1675 PF07897.6 EEQ30442.1 - 0.0088 15.9 2.4 0.011 15.5 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) DUF1751 PF08551.5 EEQ30443.1 - 3.2e-28 97.9 0.7 6.5e-28 96.9 0.5 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EEQ30443.1 - 2.3e-06 27.6 11.6 4.5e-06 26.7 8.1 1.4 1 0 0 1 1 1 1 Rhomboid family WD40 PF00400.27 EEQ30445.1 - 1.3e-06 28.0 6.4 0.0031 17.3 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.6 EEQ30445.1 - 0.0043 16.7 0.0 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF605 PF04652.11 EEQ30445.1 - 6.8 5.9 7.2 11 5.2 5.0 1.3 1 0 0 1 1 1 0 Vta1 like WD40_alt PF14077.1 EEQ30446.1 - 0.0039 16.8 0.1 0.0093 15.5 0.1 1.6 1 0 0 1 1 1 1 Alternative WD40 repeat motif Uds1 PF15456.1 EEQ30446.1 - 0.0082 16.1 1.5 0.015 15.2 1.0 1.5 1 0 0 1 1 1 1 Up-regulated During Septation Troponin PF00992.15 EEQ30446.1 - 0.0085 16.1 0.5 0.025 14.6 0.3 1.7 1 1 0 1 1 1 1 Troponin FlaC_arch PF05377.6 EEQ30446.1 - 0.019 14.8 0.2 0.055 13.3 0.0 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ATG16 PF08614.6 EEQ30446.1 - 0.019 14.7 2.8 0.019 14.7 1.2 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) EBP50_C-term PF09007.6 EEQ30446.1 - 0.073 12.9 1.1 0.6 10.0 0.0 2.5 2 0 0 2 2 2 0 EBP50, C-terminal Suppressor_APC PF11414.3 EEQ30446.1 - 0.12 12.1 3.9 0.22 11.3 0.1 2.4 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein bZIP_1 PF00170.16 EEQ30446.1 - 1.2 9.1 6.5 3.3 7.7 3.2 2.5 2 1 0 2 2 2 0 bZIP transcription factor Chorismate_bind PF00425.13 EEQ30447.1 - 4.7e-89 298.1 0.0 6.5e-89 297.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EEQ30447.1 - 3.5e-28 98.3 0.0 3.8e-25 88.5 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region ENTH PF01417.15 EEQ30448.1 - 2.6e-49 166.2 0.0 3.8e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EEQ30448.1 - 6.4e-06 25.0 0.0 1.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 EEQ30448.1 - 0.09 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Herpes_gE PF02480.11 EEQ30448.1 - 0.14 10.3 0.6 0.24 9.6 0.4 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E UIM PF02809.15 EEQ30448.1 - 0.39 10.4 5.9 0.48 10.1 0.7 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif Pkinase PF00069.20 EEQ30449.1 - 3.3e-22 78.8 0.0 1.4e-21 76.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30449.1 - 8.9e-09 34.7 0.0 0.00078 18.5 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase EABR PF12180.3 EEQ30449.1 - 0.014 14.7 0.2 0.029 13.6 0.1 1.5 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 HEAT_2 PF13646.1 EEQ30450.1 - 3.9e-07 30.2 0.1 0.016 15.4 0.2 3.9 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 EEQ30450.1 - 9.1e-07 28.4 0.6 1.2 9.3 0.0 5.4 6 0 0 6 6 5 2 HEAT repeat Adaptin_N PF01602.15 EEQ30450.1 - 2e-05 23.1 0.5 6.9e-05 21.3 0.4 2.1 1 1 0 1 1 1 1 Adaptin N terminal region TAN PF11640.3 EEQ30450.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair V_ATPase_I PF01496.14 EEQ30450.1 - 0.078 10.8 2.3 0.12 10.2 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 EEQ30450.1 - 0.09 11.4 7.3 0.16 10.6 5.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EEQ30450.1 - 0.14 11.1 10.7 0.3 10.0 7.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EEQ30450.1 - 0.48 9.9 14.8 0.064 12.8 7.2 1.7 2 0 0 2 2 2 0 IncA protein COG5 PF10392.4 EEQ30450.1 - 1.5 8.7 6.4 1.3 8.9 3.2 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 HsbA PF12296.3 EEQ30450.1 - 1.7 8.5 4.7 4.3 7.2 0.1 3.6 3 1 1 4 4 4 0 Hydrophobic surface binding protein A Atg14 PF10186.4 EEQ30450.1 - 6.1 5.6 9.3 14 4.4 6.5 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 EEQ30450.1 - 7.2 6.4 15.7 18 5.2 10.9 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ribosomal_L7Ae PF01248.21 EEQ30451.1 - 3.9e-21 74.3 0.4 6.2e-21 73.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2841 PF11001.3 EEQ30452.1 - 2.2e-43 147.0 0.0 4.4e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) HGTP_anticodon2 PF12745.2 EEQ30455.1 - 0.071 12.2 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Clat_adaptor_s PF01217.15 EEQ30457.1 - 4.8e-31 107.3 0.0 1e-30 106.3 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.18 EEQ30458.1 - 8.4e-19 67.6 0.0 1.3e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EEQ30458.1 - 2.9e-07 29.8 0.0 4.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EEQ30458.1 - 4.7e-06 26.5 0.0 0.00024 20.9 0.1 2.2 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 EEQ30458.1 - 6.4e-05 22.4 0.0 0.00048 19.6 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEQ30458.1 - 0.00013 21.1 0.0 0.00025 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EEQ30458.1 - 0.00028 20.1 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EEQ30458.1 - 0.0013 18.0 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 EEQ30458.1 - 0.0072 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.4 EEQ30458.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.27 EEQ30459.1 - 2.7e-54 179.2 14.6 3e-09 36.4 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EEQ30459.1 - 2.4e-10 39.9 0.1 5.9e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ30459.1 - 2.8e-10 39.5 0.2 5.6e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EEQ30459.1 - 0.00021 19.6 9.8 0.34 8.9 0.5 5.1 3 3 3 6 6 6 4 Nucleoporin Nup120/160 SRP9-21 PF05486.7 EEQ30459.1 - 0.064 12.9 0.2 5.5 6.8 0.1 3.7 3 1 1 4 4 4 0 Signal recognition particle 9 kDa protein (SRP9) PRANC PF09372.5 EEQ30459.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 PRANC domain HORMA PF02301.13 EEQ30460.1 - 3.2e-39 134.5 0.0 5.1e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 EEQ30460.1 - 0.00095 18.8 10.5 0.0023 17.5 7.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEQ30460.1 - 0.0031 16.7 1.7 0.0097 15.2 1.2 1.9 1 0 0 1 1 1 1 PHD-finger Nuc_sug_transp PF04142.10 EEQ30462.1 - 1.1e-67 227.7 8.2 1.1e-67 227.7 5.7 1.6 1 1 1 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 EEQ30462.1 - 0.00019 21.4 9.7 0.00019 21.4 6.7 2.7 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EEQ30462.1 - 0.0038 17.4 7.1 0.0038 17.4 5.0 3.1 3 1 1 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 EEQ30462.1 - 4.1 7.0 16.9 0.32 10.6 3.2 2.7 2 2 0 2 2 2 0 Triose-phosphate Transporter family Sec63 PF02889.11 EEQ30463.1 - 4.3e-50 170.7 0.0 7.4e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EEQ30463.1 - 3.6e-28 98.1 0.2 7.2e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ30463.1 - 1e-09 38.1 0.0 2.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ30463.1 - 4.7e-09 36.3 0.0 9.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EEQ30463.1 - 1.7e-05 23.7 0.4 5.5e-05 22.1 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EEQ30463.1 - 0.0022 18.1 0.1 0.0065 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEQ30463.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EEQ30463.1 - 0.092 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EEQ30463.1 - 0.18 11.6 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain LRR_6 PF13516.1 EEQ30464.1 - 0.0084 16.0 2.7 27 5.2 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 EEQ30464.1 - 0.09 12.8 2.8 36 4.9 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 EEQ30464.1 - 0.29 10.9 2.3 3.5 7.4 0.5 2.9 2 1 2 4 4 4 0 Leucine rich repeat Acid_PPase PF12689.2 EEQ30465.1 - 1e-68 230.2 0.0 1.2e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.13 EEQ30465.1 - 0.0012 18.5 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EEQ30465.1 - 0.048 13.8 0.7 0.8 9.9 0.0 2.8 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Hexapep PF00132.19 EEQ30466.1 - 4.4e-10 38.6 9.7 0.0011 18.3 2.9 4.3 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEQ30466.1 - 4.3e-05 22.9 6.2 0.011 15.3 1.4 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase TPR_MLP1_2 PF07926.7 EEQ30467.1 - 1.9e-31 108.5 26.9 1.9e-31 108.5 18.7 16.4 5 5 8 14 14 14 5 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EEQ30467.1 - 0.00078 19.1 16.5 0.00078 19.1 11.4 22.0 13 8 13 26 26 26 7 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EEQ30467.1 - 0.0041 16.9 14.4 0.0041 16.9 10.0 15.2 5 5 8 14 14 14 1 Tropomyosin like T2SF PF00482.18 EEQ30467.1 - 0.24 11.3 8.7 8.5 6.3 0.5 5.1 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F TFIIE_beta PF02186.10 EEQ30468.1 - 1.8e-06 27.8 0.0 6.1e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 TFIIE beta subunit core domain DHBP_synthase PF00926.14 EEQ30469.1 - 2e-73 245.8 0.0 5.1e-73 244.4 0.0 1.6 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase F-box-like PF12937.2 EEQ30470.1 - 2.7e-08 33.3 1.0 8.8e-08 31.7 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEQ30470.1 - 1.1e-07 31.3 0.2 1.1e-07 31.3 0.1 2.0 2 0 0 2 2 2 1 F-box domain Pkinase PF00069.20 EEQ30471.1 - 2.6e-60 203.7 0.0 8.8e-60 202.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30471.1 - 1e-24 87.0 0.0 1.4e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ30471.1 - 1.1e-09 37.6 0.0 1.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ30471.1 - 0.0098 14.9 0.0 0.073 12.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 EEQ30472.1 - 1.6e-48 163.6 0.0 2e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEQ30472.1 - 0.00027 20.8 0.8 0.0011 18.8 0.5 1.8 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EEQ30472.1 - 0.0016 18.2 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EEQ30472.1 - 0.0039 16.8 0.1 0.0081 15.8 0.1 1.5 1 1 0 1 1 1 1 UEV domain UFC1 PF08694.6 EEQ30472.1 - 0.16 11.4 0.0 0.7 9.3 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Nucleos_tra2_C PF07662.8 EEQ30474.1 - 3.3e-58 196.6 1.2 3.3e-58 196.6 0.8 3.2 3 2 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EEQ30474.1 - 1.5e-23 82.8 3.1 1.5e-23 82.8 2.1 2.9 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 EEQ30474.1 - 0.84 9.5 21.0 0.079 12.8 7.1 3.6 3 1 0 3 3 3 0 Nucleoside recognition Prenyltransf PF01255.14 EEQ30476.1 - 3.8e-20 71.9 0.1 1.3e-19 70.2 0.0 1.8 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase UbiA PF01040.13 EEQ30477.1 - 4.7e-15 55.5 7.9 5.8e-15 55.2 5.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Glyco_transf_20 PF00982.16 EEQ30478.1 - 3.3e-199 662.2 0.0 3.8e-199 662.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EEQ30478.1 - 0.013 14.9 0.5 0.034 13.6 0.1 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain Lactamase_B PF00753.22 EEQ30479.1 - 1.7e-17 63.6 3.1 2.8e-17 63.0 2.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEQ30479.1 - 5.1e-05 22.9 0.3 6.8e-05 22.5 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Aconitase PF00330.15 EEQ30480.1 - 1e-175 584.7 0.0 1.8e-175 583.8 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEQ30480.1 - 3e-44 150.3 0.0 5.2e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Abhydrolase_2 PF02230.11 EEQ30481.1 - 1.6e-26 93.0 0.0 1e-17 64.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EEQ30481.1 - 0.00052 19.2 0.0 0.00072 18.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEQ30481.1 - 0.0019 18.1 0.0 0.0041 17.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ30481.1 - 0.018 14.8 0.0 0.034 13.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-C2H2_jaz PF12171.3 EEQ30482.1 - 2.8e-09 36.8 3.7 2.8e-09 36.8 2.6 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEQ30482.1 - 0.017 15.2 1.7 0.026 14.6 1.2 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EEQ30482.1 - 0.076 13.2 1.8 0.076 13.2 1.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-U1 PF06220.7 EEQ30482.1 - 0.11 12.0 1.5 0.12 11.9 0.3 1.6 2 0 0 2 2 2 0 U1 zinc finger zf-C2H2_4 PF13894.1 EEQ30482.1 - 3.3 8.2 4.6 0.72 10.3 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Mito_carr PF00153.22 EEQ30483.1 - 5.9e-41 138.1 3.5 3.1e-15 55.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.18 EEQ30484.1 - 4.1e-66 222.8 0.0 5.6e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EEQ30484.1 - 2.8e-59 200.2 0.3 6.7e-59 198.9 0.2 1.6 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EEQ30484.1 - 1.6e-12 47.0 0.0 4.9e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EEQ30484.1 - 2.2e-06 26.6 0.0 1.1e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EEQ30484.1 - 0.00087 19.1 0.0 0.0031 17.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Vac14_Fig4_bd PF11916.3 EEQ30485.1 - 4.2e-84 280.2 6.4 4.2e-84 280.2 4.4 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EEQ30485.1 - 3.9e-46 155.3 0.1 3.3e-42 142.8 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EEQ30485.1 - 7.3e-08 31.8 1.8 0.12 12.5 0.0 7.3 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 EEQ30485.1 - 8.8e-07 29.2 5.7 0.02 15.3 0.0 5.9 4 1 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.1 EEQ30485.1 - 2.7e-06 27.5 3.8 0.036 14.3 0.0 4.6 5 0 0 5 5 5 2 HEAT repeats Arm PF00514.18 EEQ30485.1 - 0.043 13.6 0.1 46 4.0 0.0 4.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Glyco_hydro_47 PF01532.15 EEQ30486.1 - 4.1e-169 563.0 0.0 5.3e-169 562.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APG9 PF04109.11 EEQ30487.1 - 1.5e-113 379.4 12.3 3.2e-104 348.7 3.3 2.1 1 1 1 2 2 2 2 Autophagy protein Apg9 RasGAP PF00616.14 EEQ30489.1 - 7.4e-46 156.3 0.0 3e-45 154.3 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EEQ30489.1 - 3.4e-07 30.0 0.1 8.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain DNA_methylase PF00145.12 EEQ30490.1 - 3.7e-30 105.1 0.0 9e-30 103.9 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EEQ30490.1 - 1.5e-06 27.9 0.0 0.0042 16.8 0.0 2.9 2 0 0 2 2 2 2 BAH domain WD40 PF00400.27 EEQ30491.1 - 1.5e-10 40.5 3.2 0.00047 19.9 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EEQ30491.1 - 0.01 14.0 0.1 0.023 12.8 0.0 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 COQ9 PF08511.6 EEQ30493.1 - 2.2e-23 81.5 0.1 4.2e-23 80.6 0.1 1.5 1 0 0 1 1 1 1 COQ9 AA_permease_2 PF13520.1 EEQ30495.1 - 6.6e-50 169.8 52.3 8.1e-50 169.5 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ30495.1 - 6.7e-23 80.7 44.5 9.5e-23 80.2 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease FmdA_AmdA PF03069.10 EEQ30496.1 - 1.6e-57 194.8 0.0 1.1e-29 103.2 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family LeuA_dimer PF08502.5 EEQ30496.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain RRM_1 PF00076.17 EEQ30498.1 - 9.2e-14 50.8 0.0 0.00075 19.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ30498.1 - 4e-09 36.3 0.0 8.1e-05 22.5 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ30498.1 - 2.8e-05 23.8 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prominin PF05478.6 EEQ30499.1 - 0.23 8.9 0.2 0.32 8.4 0.2 1.1 1 0 0 1 1 1 0 Prominin RPT PF13446.1 EEQ30501.1 - 2.8e-50 167.5 0.3 1.8e-21 75.3 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.24 EEQ30501.1 - 1.1e-47 162.3 0.0 2.4e-47 161.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ30501.1 - 2.5e-10 40.2 0.3 4.7e-07 29.5 0.2 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 EEQ30501.1 - 3e-05 23.7 0.0 7.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 PUB domain AAA_14 PF13173.1 EEQ30501.1 - 0.12 12.3 0.7 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain CoA_trans PF01144.18 EEQ30502.1 - 7.7e-105 348.8 2.5 2.8e-64 216.2 0.5 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2370 PF10176.4 EEQ30504.1 - 8.3e-85 283.8 0.0 1.2e-84 283.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 EEQ30504.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Rb_C PF08934.5 EEQ30505.1 - 0.0037 16.9 0.4 0.008 15.8 0.3 1.5 1 0 0 1 1 1 1 Rb C-terminal domain WSC PF01822.14 EEQ30506.1 - 4.1e-09 36.2 6.3 7.8e-09 35.3 4.3 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 EEQ30506.1 - 5.1e-09 35.3 0.4 1.1e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 EEQ30506.1 - 0.016 14.6 0.1 0.034 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4366 PF14283.1 EEQ30506.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CDP-OH_P_transf PF01066.16 EEQ30508.1 - 2.9e-12 46.7 1.2 5.8e-12 45.8 0.8 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.9 EEQ30509.1 - 7e-42 142.4 2.3 8.1e-42 142.2 0.0 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EEQ30510.1 - 4e-43 146.9 0.1 6.7e-43 146.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ30510.1 - 2.4e-16 59.4 0.1 4.6e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EEQ30510.1 - 9.2e-13 47.8 0.0 1.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EEQ30510.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain Fungal_trans PF04082.13 EEQ30511.1 - 1.5e-23 82.9 0.2 4.6e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ30511.1 - 9.1e-10 38.2 13.3 1.7e-09 37.4 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CytochromB561_N PF09786.4 EEQ30511.1 - 0.25 9.7 10.5 0.063 11.7 1.2 2.2 2 0 0 2 2 2 0 Cytochrome B561, N terminal Peptidase_M41 PF01434.13 EEQ30512.1 - 2.6e-75 252.5 0.1 5.2e-75 251.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EEQ30512.1 - 6.3e-42 142.8 0.0 1.8e-41 141.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EEQ30512.1 - 4.7e-09 36.4 0.1 4.7e-09 36.4 0.0 2.3 3 0 0 3 3 2 1 FtsH Extracellular AAA_22 PF13401.1 EEQ30512.1 - 0.00042 20.4 1.4 0.2 11.7 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 EEQ30512.1 - 0.0014 18.3 0.1 0.0075 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EEQ30512.1 - 0.0034 17.1 0.2 0.011 15.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EEQ30512.1 - 0.0035 16.7 0.3 0.031 13.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EEQ30512.1 - 0.0082 15.5 0.0 0.019 14.3 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EEQ30512.1 - 0.015 14.0 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus RuvB_N PF05496.7 EEQ30512.1 - 0.022 13.8 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EEQ30512.1 - 0.026 15.3 0.0 0.15 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EEQ30512.1 - 0.028 14.3 1.9 0.12 12.3 0.1 2.6 2 1 1 3 3 3 0 AAA ATPase domain Pex14_N PF04695.8 EEQ30512.1 - 0.034 14.2 0.7 0.034 14.2 0.5 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_14 PF13173.1 EEQ30512.1 - 0.074 12.9 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEQ30512.1 - 0.13 12.1 0.5 0.84 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain RNase_H2-Ydr279 PF09468.5 EEQ30512.1 - 2.5 7.2 13.8 4.5 6.3 9.6 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1295 PF06966.7 EEQ30513.1 - 9.1e-40 136.4 7.9 1.2e-39 135.9 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EEQ30513.1 - 0.13 12.4 4.4 0.29 11.3 0.0 3.3 3 1 1 4 4 4 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4181 PF13789.1 EEQ30513.1 - 8 6.4 14.8 0.076 12.9 0.6 3.5 3 2 0 3 3 3 0 Domain of unknown function (DUF4181) Topoisom_bac PF01131.15 EEQ30514.1 - 1.9e-80 270.7 0.0 2.3e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EEQ30514.1 - 2.1e-13 50.1 0.0 4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Baculo_PEP_C PF04513.7 EEQ30515.1 - 0.0017 18.1 20.9 0.38 10.5 0.1 5.1 2 1 2 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Endonuc-PvuII PF09225.5 EEQ30515.1 - 0.09 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease PvuII Matrilin_ccoil PF10393.4 EEQ30515.1 - 0.24 10.8 4.6 1.8 8.0 0.1 3.7 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Vac_Fusion PF02346.11 EEQ30515.1 - 0.31 10.4 8.7 0.64 9.4 0.1 4.8 5 1 0 5 5 5 0 Chordopoxvirus fusion protein Kdo PF06293.9 EEQ30518.1 - 4.4e-05 22.6 1.2 7.6e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEQ30518.1 - 0.007 15.5 0.0 0.007 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.15 EEQ30518.1 - 0.045 13.3 2.8 0.16 11.4 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 EEQ30518.1 - 0.12 12.0 0.1 0.12 12.0 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Borrelia_P83 PF05262.6 EEQ30518.1 - 1.4 7.1 16.3 2.1 6.5 11.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4149 PF13664.1 EEQ30519.1 - 4.5e-26 90.8 1.9 6.7e-26 90.2 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku PF02735.11 EEQ30520.1 - 4.3e-25 88.2 0.0 7.9e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EEQ30520.1 - 1.9e-15 56.8 0.4 4.3e-15 55.6 0.2 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 EEQ30520.1 - 2.3e-14 53.3 0.0 7.8e-14 51.6 0.0 1.9 2 1 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain PX PF00787.19 EEQ30521.1 - 7.3e-17 61.1 0.0 1.8e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EEQ30521.1 - 0.00028 20.4 0.8 0.00076 19.1 0.5 1.8 1 0 0 1 1 1 1 SNARE domain tRNA-synt_2 PF00152.15 EEQ30522.1 - 1.1e-69 234.7 0.4 1.1e-69 234.7 0.3 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ30522.1 - 3e-07 30.2 0.0 6.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Sin_N PF04801.8 EEQ30522.1 - 0.042 12.7 5.2 0.066 12.0 3.6 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Hydrolase_6 PF13344.1 EEQ30523.1 - 7.5e-24 83.5 0.0 2.2e-23 82.0 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ30523.1 - 1.6e-13 50.1 0.0 2.2e-12 46.5 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EEQ30523.1 - 0.00088 19.5 0.1 0.23 11.6 0.0 3.1 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ30523.1 - 0.068 13.5 0.0 1.6 9.0 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase F-box-like PF12937.2 EEQ30524.1 - 2.4e-10 39.9 0.3 7.7e-10 38.3 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EEQ30524.1 - 0.0033 17.0 0.0 0.56 9.8 0.0 3.4 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) Adaptin_N PF01602.15 EEQ30525.1 - 2.2e-113 379.3 0.4 2.9e-113 378.9 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EEQ30525.1 - 8.2e-61 204.2 1.9 1.9e-60 203.0 1.3 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EEQ30525.1 - 3.6e-14 52.8 4.7 3.5e-05 23.9 0.0 5.8 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 EEQ30525.1 - 0.00024 20.9 6.7 0.55 10.4 0.3 5.7 5 0 0 5 5 5 2 HEAT repeat Alpha_adaptin_C PF02296.11 EEQ30525.1 - 0.0028 17.5 0.0 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.1 EEQ30525.1 - 0.0052 17.2 3.5 0.019 15.4 0.6 3.0 3 0 0 3 3 3 1 HEAT-like repeat HEAT_PBS PF03130.11 EEQ30525.1 - 0.016 15.6 4.7 3.2 8.4 0.1 4.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Phosducin PF02114.11 EEQ30526.1 - 9.9e-15 53.9 0.0 1.2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Phosducin DUF3503 PF12011.3 EEQ30526.1 - 0.031 14.0 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3503) Pup PF05639.6 EEQ30526.1 - 0.91 10.0 5.7 0.17 12.3 1.0 1.9 2 0 0 2 2 2 0 Pup-like protein bZIP_1 PF00170.16 EEQ30527.1 - 1e-05 25.4 13.6 1.7e-05 24.7 9.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor TMF_TATA_bd PF12325.3 EEQ30527.1 - 0.018 14.7 3.9 0.031 14.0 2.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_Maf PF03131.12 EEQ30527.1 - 0.019 15.2 11.0 0.03 14.6 7.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor GAS PF13851.1 EEQ30527.1 - 0.053 12.7 5.1 0.076 12.2 3.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Glutaredoxin2_C PF04399.8 EEQ30527.1 - 0.084 12.4 1.4 0.14 11.7 1.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_2 PF07716.10 EEQ30527.1 - 0.12 12.2 16.7 0.15 11.9 11.0 1.6 1 1 1 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 EEQ30527.1 - 0.21 11.9 2.3 0.35 11.2 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) PAP1 PF08601.5 EEQ30527.1 - 5.1 6.6 11.8 1.4e+02 1.9 8.1 2.5 1 1 0 1 1 1 0 Transcription factor PAP1 Bap31 PF05529.7 EEQ30527.1 - 5.7 6.3 6.0 8.2 5.8 4.2 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Pkinase PF00069.20 EEQ30528.1 - 2.4e-38 131.7 0.0 3e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30528.1 - 7.5e-14 51.4 0.0 1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ30528.1 - 2e-05 24.4 0.0 0.0015 18.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EEQ30528.1 - 0.053 12.3 0.1 0.082 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 EEQ30529.1 - 6.4e-23 81.0 62.5 3.3e-17 62.2 27.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kelch_5 PF13854.1 EEQ30530.1 - 4.2e-33 112.7 3.5 9.2e-09 35.0 0.1 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 EEQ30530.1 - 1.4e-29 101.3 1.3 9.5e-12 44.2 0.3 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EEQ30530.1 - 1.8e-29 101.1 21.1 3.5e-08 33.3 0.4 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EEQ30530.1 - 2e-28 97.9 12.5 7.4e-08 32.0 1.1 5.9 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EEQ30530.1 - 5.6e-23 80.1 5.6 4.5e-11 42.4 0.7 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EEQ30530.1 - 1.2e-22 78.6 5.1 3.1e-08 33.0 0.3 5.6 5 0 0 5 5 5 4 Kelch motif zf-DHHC PF01529.15 EEQ30530.1 - 0.44 9.9 2.2 0.95 8.8 1.6 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase BAF1_ABF1 PF04684.8 EEQ30530.1 - 3.6 6.3 47.5 3.4 6.4 23.6 2.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF4396 PF14342.1 EEQ30531.1 - 9.2e-45 152.1 4.2 1.1e-44 151.8 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Raptor_N PF14538.1 EEQ30532.1 - 6.5e-65 217.6 0.0 1.1e-64 216.9 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EEQ30532.1 - 1.2e-06 28.1 3.2 0.3 11.0 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.1 EEQ30532.1 - 0.00093 19.4 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.17 EEQ30532.1 - 0.0011 18.8 4.4 0.073 13.1 0.0 3.6 4 0 0 4 4 4 2 HEAT repeat Peptidase_C14 PF00656.17 EEQ30532.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Atx10homo_assoc PF09759.4 EEQ30532.1 - 0.021 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain DUF1546 PF07571.8 EEQ30532.1 - 0.073 13.1 0.0 0.44 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) zf-RING_2 PF13639.1 EEQ30535.1 - 2.6e-14 52.7 5.7 4.1e-14 52.1 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EEQ30535.1 - 6.6e-11 41.7 0.3 1.6e-10 40.5 0.0 1.8 2 0 0 2 2 1 1 PA domain zf-C3HC4_2 PF13923.1 EEQ30535.1 - 1.6e-09 37.6 5.3 2.5e-09 37.0 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ30535.1 - 3.5e-09 36.6 1.8 6.4e-09 35.7 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEQ30535.1 - 1.5e-08 34.1 4.0 2.4e-08 33.4 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ30535.1 - 3.3e-08 33.0 3.3 4.9e-08 32.5 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ30535.1 - 9.3e-08 31.6 3.1 1.4e-07 31.0 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEQ30535.1 - 0.00043 20.0 0.5 0.00079 19.2 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EEQ30535.1 - 0.013 15.1 3.4 0.028 14.1 2.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEQ30535.1 - 0.038 13.8 3.3 0.099 12.5 2.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EEQ30535.1 - 0.049 13.5 2.7 0.12 12.3 1.9 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2029 PF09594.5 EEQ30535.1 - 0.055 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) RINGv PF12906.2 EEQ30535.1 - 0.056 13.5 4.4 0.1 12.6 3.0 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EEQ30535.1 - 0.3 10.7 3.1 0.51 9.9 2.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EEQ30535.1 - 0.89 9.2 3.4 1.6 8.5 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EEQ30535.1 - 2.2 8.3 3.8 4.2 7.4 2.7 1.5 1 0 0 1 1 1 0 RING-like domain EI24 PF07264.6 EEQ30536.1 - 4.8e-05 22.8 10.3 0.00024 20.6 7.2 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LysM PF01476.15 EEQ30537.1 - 8.5e-08 31.9 0.0 2.7e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 LysM domain FAD_binding_3 PF01494.14 EEQ30538.1 - 2.2e-11 43.3 0.0 4e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEQ30538.1 - 1e-06 27.9 0.2 5.9e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ30538.1 - 4.5e-05 23.3 0.1 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEQ30538.1 - 0.0024 16.5 0.4 0.004 15.8 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EEQ30538.1 - 0.023 14.5 0.1 0.054 13.3 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ30538.1 - 0.063 13.0 0.1 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF1967 PF09269.6 EEQ30538.1 - 0.12 12.0 1.4 0.4 10.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) FHA PF00498.21 EEQ30539.1 - 4.9e-16 58.6 0.0 9.3e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain ERM PF00769.14 EEQ30539.1 - 0.2 11.1 26.6 1.4 8.3 10.0 2.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF2664 PF10867.3 EEQ30539.1 - 0.93 10.1 5.6 14 6.3 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) GrpE PF01025.14 EEQ30539.1 - 1.2 8.6 16.1 0.049 13.1 2.6 2.4 2 0 0 2 2 2 0 GrpE CENP-Q PF13094.1 EEQ30539.1 - 2.1 8.3 33.2 0.27 11.2 6.7 3.0 2 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Romo1 PF10247.4 EEQ30540.1 - 1.7e-21 76.2 9.9 2.4e-21 75.6 6.8 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Iron_permease PF04120.7 EEQ30542.1 - 1.5e-38 131.3 6.2 2.7e-20 72.3 0.0 4.2 4 0 0 4 4 4 4 Low affinity iron permease DUF4006 PF13179.1 EEQ30542.1 - 1.1 8.8 3.6 0.86 9.2 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF4006) LRR_8 PF13855.1 EEQ30543.1 - 2.6e-13 49.4 11.9 1.1e-07 31.4 0.4 2.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EEQ30543.1 - 3.9e-08 32.7 0.5 3.9e-08 32.7 0.3 2.6 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEQ30543.1 - 0.00014 21.4 4.2 1 9.6 0.1 4.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EEQ30543.1 - 0.024 14.7 6.1 4.3 7.9 0.0 4.4 5 0 0 5 5 5 0 Leucine rich repeat Arb2 PF09757.4 EEQ30544.1 - 4e-32 111.0 0.0 6e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Ribosomal_S14 PF00253.16 EEQ30545.1 - 8.5e-18 63.4 0.2 5e-16 57.8 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e Bot1p PF12298.3 EEQ30545.1 - 0.1 12.5 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein DASH_Spc19 PF08287.6 EEQ30546.1 - 1.2e-50 171.0 0.2 1.6e-50 170.6 0.1 1.2 1 0 0 1 1 1 1 Spc19 COG2 PF06148.6 EEQ30546.1 - 0.01 15.6 1.6 0.04 13.7 0.1 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.6 EEQ30546.1 - 0.12 12.2 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) WBS28 PF15164.1 EEQ30546.1 - 0.13 11.2 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue Rsm22 PF09243.5 EEQ30547.1 - 1.7e-29 102.7 0.0 1e-28 100.2 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Nucleo_P87 PF07267.6 EEQ30547.1 - 0.078 11.6 2.4 0.13 10.9 1.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2416 PF10315.4 EEQ30547.1 - 0.18 12.0 0.8 0.36 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2416) BNR_2 PF13088.1 EEQ30548.1 - 3.1e-27 95.5 0.1 3.9e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.1 EEQ30548.1 - 7.6e-10 38.3 0.0 1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain Rogdi_lz PF10259.4 EEQ30549.1 - 1.3e-75 254.0 0.0 1.4e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Mito_fiss_reg PF05308.6 EEQ30549.1 - 0.097 12.0 0.1 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator HSP70 PF00012.15 EEQ30550.1 - 2.4e-75 253.6 1.6 2.4e-75 253.6 1.1 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ30550.1 - 5.1e-12 45.0 1.5 7.8e-12 44.4 1.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.1 EEQ30550.1 - 0.015 14.6 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein CENP-B_dimeris PF09026.5 EEQ30550.1 - 0.015 15.4 1.7 0.034 14.3 1.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BRAP2 PF07576.7 EEQ30550.1 - 0.07 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 Nucleoplasmin PF03066.10 EEQ30550.1 - 0.12 11.8 6.2 0.049 13.1 2.4 1.7 2 0 0 2 2 2 0 Nucleoplasmin FAM176 PF14851.1 EEQ30550.1 - 8.6 6.0 9.7 0.25 11.0 1.0 2.5 3 0 0 3 3 3 0 FAM176 family Phtf-FEM1B_bdg PF12129.3 EEQ30551.1 - 0.075 12.3 2.1 0.15 11.4 1.4 1.4 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor MpPF26 PF07666.6 EEQ30551.1 - 0.38 10.6 6.0 0.16 11.9 1.6 2.3 2 1 0 2 2 2 0 M penetrans paralogue family 26 DUF1290 PF06947.7 EEQ30551.1 - 1.6 8.7 5.6 3.6 7.5 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1290) p450 PF00067.17 EEQ30552.1 - 8e-20 70.7 0.0 1e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynamin_M PF01031.15 EEQ30552.1 - 0.076 11.7 0.0 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 Dynamin central region DUF4116 PF13475.1 EEQ30552.1 - 0.14 11.6 0.0 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF4267 PF14087.1 EEQ30555.1 - 2.8e-26 91.3 5.6 3.2e-26 91.1 3.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) MFS_1 PF07690.11 EEQ30556.1 - 7.8e-39 133.3 55.4 1.3e-38 132.6 36.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ30556.1 - 3.7e-17 62.0 11.5 3.7e-17 62.0 7.9 3.6 2 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 EEQ30556.1 - 1.6e-12 46.4 14.7 1.6e-12 46.4 10.2 1.6 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HNH_2 PF13391.1 EEQ30557.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease Rpp20 PF12328.3 EEQ30558.1 - 2.4e-47 160.1 1.3 3.4e-47 159.7 0.9 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EEQ30558.1 - 9.1e-18 63.6 0.6 1.9e-17 62.6 0.4 1.6 1 0 0 1 1 1 1 Alba PhzC-PhzF PF02567.11 EEQ30561.1 - 0.00049 19.4 0.2 0.0097 15.1 0.1 2.1 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein DUF305 PF03713.8 EEQ30561.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF305) UDP-g_GGTase PF06427.6 EEQ30563.1 - 4.9e-68 228.5 0.0 9.5e-68 227.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EEQ30563.1 - 0.00018 20.9 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1416 PF07210.7 EEQ30563.1 - 0.22 11.1 0.0 0.98 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) Amidohydro_1 PF01979.15 EEQ30564.1 - 1.7e-20 73.9 0.0 2.2e-19 70.3 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EEQ30564.1 - 2.7e-16 60.4 0.0 2.8e-15 57.1 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EEQ30564.1 - 4.2e-09 36.1 0.0 9.6e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EEQ30564.1 - 1.8e-05 24.1 0.0 0.036 13.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_26 PF02156.10 EEQ30564.1 - 0.034 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Vma12 PF11712.3 EEQ30565.1 - 2.1e-35 121.5 0.0 3e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase MARVEL PF01284.18 EEQ30565.1 - 0.086 12.6 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Membrane-associating domain Prefoldin PF02996.12 EEQ30566.1 - 1.3e-29 102.2 0.2 2.2e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EEQ30566.1 - 0.0054 16.4 0.4 0.055 13.2 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit DUF4559 PF15112.1 EEQ30566.1 - 0.039 13.1 1.0 0.089 11.9 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) DMPK_coil PF08826.5 EEQ30566.1 - 0.067 13.0 2.2 2.1 8.2 0.3 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Glyco_transf_28 PF03033.15 EEQ30567.1 - 5.2e-25 87.8 0.0 9.9e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EEQ30567.1 - 0.0017 17.0 0.1 0.0025 16.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Prenylcys_lyase PF07156.9 EEQ30568.1 - 4.1e-45 154.2 0.0 1.9e-44 152.0 0.0 2.0 1 1 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.19 EEQ30568.1 - 2.3e-11 43.4 0.0 2.6e-10 39.9 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEQ30568.1 - 6.7e-11 42.0 0.0 1.7e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEQ30568.1 - 0.00051 19.8 0.0 0.0099 15.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEQ30568.1 - 0.0029 17.5 0.1 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ30568.1 - 0.0075 15.2 0.1 0.18 10.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEQ30568.1 - 0.042 12.9 0.1 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PDCD2_C PF04194.8 EEQ30569.1 - 1.5e-50 170.9 0.2 4.1e-50 169.5 0.0 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain PCI_Csn8 PF10075.4 EEQ30570.1 - 3.7e-43 146.7 0.0 5.1e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EEQ30570.1 - 1.4e-22 80.2 0.0 1.8e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Folliculin PF11704.3 EEQ30571.1 - 5.1e-43 146.5 0.0 7.4e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Clp1 PF06807.9 EEQ30572.1 - 0.00099 18.9 0.0 0.084 12.6 0.0 2.3 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 AAA_33 PF13671.1 EEQ30572.1 - 0.002 17.9 0.2 0.078 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEQ30572.1 - 0.018 14.7 0.0 0.051 13.2 0.0 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EEQ30572.1 - 0.02 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EEQ30572.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RNA_polI_A34 PF08208.6 EEQ30573.1 - 5.9e-34 117.4 7.0 5.9e-34 117.4 4.9 3.3 2 2 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 SHMT PF00464.14 EEQ30574.1 - 1.2e-206 685.7 0.0 1.4e-206 685.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EEQ30574.1 - 8.5e-06 24.9 0.0 2.8e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ30574.1 - 6.6e-05 21.8 0.0 9.9e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V IL3 PF02059.10 EEQ30574.1 - 0.02 14.8 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 Interleukin-3 Beta_elim_lyase PF01212.16 EEQ30574.1 - 0.026 13.6 0.0 0.058 12.5 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase DUF3040 PF11239.3 EEQ30574.1 - 0.036 14.1 0.2 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) AHH PF14412.1 EEQ30574.1 - 0.085 12.8 0.7 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Med9 PF07544.8 EEQ30575.1 - 1.7e-22 78.9 0.3 3.2e-22 78.0 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EEQ30575.1 - 0.016 14.8 0.1 0.016 14.7 0.1 1.1 1 0 0 1 1 1 0 IncA protein Med21 PF11221.3 EEQ30575.1 - 0.026 14.4 0.7 0.026 14.4 0.5 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex SlyX PF04102.7 EEQ30575.1 - 0.03 14.7 0.5 0.071 13.4 0.4 1.6 1 0 0 1 1 1 0 SlyX DASH_Spc34 PF08657.5 EEQ30575.1 - 0.043 13.4 1.5 0.066 12.8 1.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 DivIC PF04977.10 EEQ30575.1 - 0.072 12.5 1.0 0.11 12.0 0.7 1.3 1 0 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.4 EEQ30575.1 - 0.081 12.7 0.4 0.12 12.2 0.3 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4140 PF13600.1 EEQ30575.1 - 0.13 12.6 0.8 0.2 12.0 0.5 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) AKNA PF12443.3 EEQ30575.1 - 0.15 12.1 0.5 0.38 10.8 0.3 1.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor Metalloenzyme PF01676.13 EEQ30576.1 - 5.3e-73 245.4 0.0 6.1e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EEQ30576.1 - 3.9e-71 238.9 0.0 5.2e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EEQ30576.1 - 2.6e-06 27.0 0.0 4.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEQ30576.1 - 0.0003 20.0 0.0 0.0044 16.2 0.0 2.5 2 1 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.15 EEQ30576.1 - 0.0045 15.7 0.0 0.054 12.1 0.0 2.1 2 0 0 2 2 2 1 Alkaline phosphatase Prefoldin_2 PF01920.15 EEQ30577.1 - 8.1e-22 76.9 17.3 1.1e-21 76.5 12.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EEQ30577.1 - 3.4e-06 26.7 7.7 5e-06 26.2 5.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EEQ30577.1 - 0.0016 18.0 18.8 0.083 12.4 13.1 2.0 1 1 0 1 1 1 1 IncA protein Prefoldin PF02996.12 EEQ30577.1 - 0.0017 18.0 13.6 0.0017 17.9 0.5 2.4 2 1 0 2 2 2 1 Prefoldin subunit DUF972 PF06156.8 EEQ30577.1 - 0.0039 17.5 9.9 0.15 12.3 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF972) Spc24 PF08286.6 EEQ30577.1 - 0.012 15.3 16.1 0.02 14.5 5.0 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Osmo_CC PF08946.5 EEQ30577.1 - 0.013 15.5 3.0 0.013 15.5 2.1 2.6 2 1 0 2 2 2 0 Osmosensory transporter coiled coil NPV_P10 PF05531.7 EEQ30577.1 - 0.014 15.6 8.7 0.51 10.6 1.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spore_YpjB PF09577.5 EEQ30577.1 - 0.014 14.9 3.2 0.018 14.6 2.2 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Tropomyosin_1 PF12718.2 EEQ30577.1 - 0.015 15.1 17.6 0.075 12.8 6.1 2.1 2 0 0 2 2 2 0 Tropomyosin like Lzipper-MIP1 PF14389.1 EEQ30577.1 - 0.028 14.5 3.4 0.028 14.5 2.4 2.8 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4349 PF14257.1 EEQ30577.1 - 0.054 12.7 0.2 0.054 12.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Spc7 PF08317.6 EEQ30577.1 - 0.079 11.6 12.6 0.1 11.2 8.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GrpE PF01025.14 EEQ30577.1 - 0.09 12.3 10.8 0.86 9.1 2.7 2.1 2 0 0 2 2 2 0 GrpE AAA_27 PF13514.1 EEQ30577.1 - 0.11 10.1 12.1 0.12 9.9 8.4 1.0 1 0 0 1 1 1 0 AAA domain DivIC PF04977.10 EEQ30577.1 - 0.12 11.8 20.7 0.73 9.3 0.8 3.1 2 1 1 3 3 3 0 Septum formation initiator CALCOCO1 PF07888.6 EEQ30577.1 - 0.16 10.2 10.2 0.19 9.9 7.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DegS PF05384.6 EEQ30577.1 - 0.19 10.9 9.1 0.44 9.7 2.2 2.1 2 0 0 2 2 2 0 Sensor protein DegS TMF_DNA_bd PF12329.3 EEQ30577.1 - 0.2 11.4 17.0 0.88 9.4 0.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HDV_ag PF01517.13 EEQ30577.1 - 0.21 11.2 2.6 0.69 9.5 1.8 1.8 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen COG2 PF06148.6 EEQ30577.1 - 0.21 11.4 8.2 0.83 9.5 1.7 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin PF00261.15 EEQ30577.1 - 0.27 10.2 15.2 0.63 9.0 1.1 2.0 2 0 0 2 2 2 0 Tropomyosin DUF4201 PF13870.1 EEQ30577.1 - 0.27 10.6 10.8 0.27 10.6 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3166 PF11365.3 EEQ30577.1 - 0.29 11.6 7.3 0.44 11.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) DUF3727 PF12527.3 EEQ30577.1 - 0.31 11.1 4.8 2.4 8.3 2.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3727) FliJ PF02050.11 EEQ30577.1 - 0.33 11.0 16.8 1.6 8.7 0.3 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein CENP-H PF05837.7 EEQ30577.1 - 0.34 11.1 7.8 1.2 9.3 0.3 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ATG16 PF08614.6 EEQ30577.1 - 0.34 10.7 12.7 1.3 8.7 2.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 EEQ30577.1 - 0.35 10.5 16.8 0.18 11.4 4.8 2.0 1 1 0 2 2 2 0 Mnd1 family Ded_cyto PF06920.8 EEQ30577.1 - 0.36 10.1 8.9 2.8 7.2 1.9 2.0 2 0 0 2 2 2 0 Dedicator of cytokinesis Laminin_II PF06009.7 EEQ30577.1 - 0.41 10.3 9.9 2.1 8.1 0.2 2.0 1 1 0 2 2 2 0 Laminin Domain II SlyX PF04102.7 EEQ30577.1 - 0.49 10.8 12.7 1.7 9.0 0.2 2.9 2 1 0 2 2 2 0 SlyX DUF4463 PF14703.1 EEQ30577.1 - 0.52 10.8 3.3 0.86 10.1 2.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) Rab5-bind PF09311.6 EEQ30577.1 - 0.59 10.0 13.0 4.1 7.2 0.3 2.1 2 0 0 2 2 2 0 Rabaptin-like protein CENP-F_leu_zip PF10473.4 EEQ30577.1 - 0.62 9.9 14.8 1 9.2 3.7 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.4 EEQ30577.1 - 0.62 9.0 15.2 3.7 6.5 10.5 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DUF3584 PF12128.3 EEQ30577.1 - 0.64 7.2 11.9 0.82 6.9 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlxA PF14282.1 EEQ30577.1 - 0.68 9.9 21.5 0.58 10.1 3.1 2.5 2 0 0 2 2 2 0 FlxA-like protein DUF4164 PF13747.1 EEQ30577.1 - 0.69 10.0 12.5 0.38 10.9 4.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) COG5 PF10392.4 EEQ30577.1 - 0.71 9.8 4.6 2.8 7.9 0.6 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 YgaB PF14182.1 EEQ30577.1 - 0.75 10.0 17.2 0.074 13.2 2.7 2.2 2 0 0 2 2 2 0 YgaB-like protein T2SM PF04612.7 EEQ30577.1 - 0.78 9.5 5.6 0.62 9.8 1.5 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Seryl_tRNA_N PF02403.17 EEQ30577.1 - 0.85 9.6 13.0 2.5 8.1 3.3 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FemAB PF02388.11 EEQ30577.1 - 0.94 8.0 14.3 0.25 10.0 4.1 2.0 1 1 1 2 2 2 0 FemAB family Uds1 PF15456.1 EEQ30577.1 - 0.96 9.4 8.9 2.5 8.1 6.2 1.8 1 1 0 1 1 1 0 Up-regulated During Septation Occludin_ELL PF07303.8 EEQ30577.1 - 0.99 10.1 9.2 1.8 9.3 2.6 2.2 1 1 1 2 2 2 0 Occludin homology domain DUF4140 PF13600.1 EEQ30577.1 - 1.1 9.6 13.8 2.4 8.6 0.3 2.3 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mto2_bdg PF12808.2 EEQ30577.1 - 1.1 9.3 5.1 9.4 6.4 0.4 2.6 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Peptidase_S49_N PF08496.5 EEQ30577.1 - 1.2 8.9 10.0 1.9 8.2 6.8 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal MtrG PF04210.8 EEQ30577.1 - 1.2 8.9 4.5 0.76 9.4 0.8 2.3 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G BLOC1_2 PF10046.4 EEQ30577.1 - 1.3 9.1 12.7 3.6 7.8 3.4 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 EEQ30577.1 - 1.8 8.9 15.4 0.76 10.1 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF3571 PF12095.3 EEQ30577.1 - 1.9 8.7 7.1 9.4 6.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) LLC1 PF14945.1 EEQ30577.1 - 1.9 8.8 4.5 17 5.7 0.8 2.1 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF948 PF06103.6 EEQ30577.1 - 2.1 8.2 6.8 5.2 7.0 0.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.8 EEQ30577.1 - 2.2 7.2 9.2 2.7 6.9 6.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Kinetocho_Slk19 PF12709.2 EEQ30577.1 - 2.4 8.3 13.5 7.3 6.7 0.2 3.1 2 1 1 3 3 3 0 Central kinetochore-associated Tektin PF03148.9 EEQ30577.1 - 2.7 6.4 12.4 1.2 7.5 1.1 2.1 2 0 0 2 2 2 0 Tektin family MutS_IV PF05190.13 EEQ30577.1 - 2.8 8.1 7.3 6.1 7.0 0.2 2.3 2 0 0 2 2 2 0 MutS family domain IV Siah-Interact_N PF09032.6 EEQ30577.1 - 2.8 8.0 14.2 4.1 7.5 0.7 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal Rootletin PF15035.1 EEQ30577.1 - 2.8 7.8 14.9 4.4 7.2 5.5 2.7 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion APG6 PF04111.7 EEQ30577.1 - 2.9 6.8 18.3 0.63 9.0 2.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Pox_F11 PF04943.7 EEQ30577.1 - 3.3 6.4 5.3 5.1 5.8 3.7 1.3 1 1 0 1 1 1 0 Poxvirus F11 protein TMF_TATA_bd PF12325.3 EEQ30577.1 - 3.6 7.3 17.9 1.4 8.7 6.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.1 EEQ30577.1 - 3.8 7.5 17.0 13 5.8 11.8 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ERp29 PF07749.7 EEQ30577.1 - 4.1 8.0 7.1 16 6.2 4.9 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain TBPIP PF07106.8 EEQ30577.1 - 4.3 6.8 16.3 5.6 6.4 1.6 2.1 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 EEQ30577.1 - 4.4 7.5 11.5 4.6 7.4 0.5 2.2 2 0 0 2 2 2 0 Syntaxin TPR_MLP1_2 PF07926.7 EEQ30577.1 - 4.5 7.0 19.4 9.5 5.9 1.0 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.1 EEQ30577.1 - 4.7 6.8 11.3 1.5 8.4 0.5 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 GAS PF13851.1 EEQ30577.1 - 5 6.2 18.0 0.96 8.6 5.3 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EEQ30577.1 - 5.8 6.7 11.1 7.5 6.3 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) End3 PF12761.2 EEQ30577.1 - 5.9 6.4 11.4 9.1 5.8 7.9 1.3 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 ADIP PF11559.3 EEQ30577.1 - 6.3 6.6 16.1 3.1 7.6 1.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CCDC155 PF14662.1 EEQ30577.1 - 6.5 6.2 17.9 20 4.7 12.4 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Ax_dynein_light PF10211.4 EEQ30577.1 - 7.4 6.3 15.5 6.2 6.6 4.5 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF848 PF05852.6 EEQ30577.1 - 8.3 6.2 10.3 2.8 7.7 2.6 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2968 PF11180.3 EEQ30577.1 - 9.4 5.5 16.0 6.9 6.0 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) AAA PF00004.24 EEQ30578.1 - 7e-43 145.9 0.0 1.2e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EEQ30578.1 - 9.5e-26 89.4 0.1 4.3e-25 87.3 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EEQ30578.1 - 9.7e-22 76.6 1.5 3.1e-21 75.0 0.8 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EEQ30578.1 - 9.3e-07 29.6 0.0 1.8e-05 25.5 0.0 2.7 2 1 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EEQ30578.1 - 1.4e-05 24.2 0.0 2.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EEQ30578.1 - 1.7e-05 24.9 0.1 0.0015 18.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ30578.1 - 2.3e-05 24.1 0.0 0.00012 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ30578.1 - 2.4e-05 24.3 0.0 0.00028 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EEQ30578.1 - 2.6e-05 24.1 0.0 7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ30578.1 - 2.8e-05 23.6 0.0 5.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EEQ30578.1 - 0.00018 20.3 0.0 0.00026 19.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EEQ30578.1 - 0.00018 20.9 0.2 0.19 11.0 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EEQ30578.1 - 0.00034 20.6 0.0 0.0025 17.8 0.0 2.2 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 EEQ30578.1 - 0.00053 19.0 0.0 0.0037 16.2 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EEQ30578.1 - 0.00055 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEQ30578.1 - 0.0022 18.1 0.0 0.0083 16.2 0.0 2.0 2 0 0 2 2 1 1 RNA helicase KaiC PF06745.8 EEQ30578.1 - 0.003 16.7 0.0 3.3 6.7 0.0 2.9 1 1 2 3 3 3 1 KaiC AAA_24 PF13479.1 EEQ30578.1 - 0.0031 17.1 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEQ30578.1 - 0.0043 17.3 0.1 0.02 15.2 0.0 2.2 3 0 0 3 3 1 1 AAA domain Arch_ATPase PF01637.13 EEQ30578.1 - 0.02 14.5 0.1 0.46 10.1 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 EEQ30578.1 - 0.027 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EEQ30578.1 - 0.03 13.4 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EEQ30578.1 - 0.032 13.8 0.0 0.47 10.1 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 EEQ30578.1 - 0.036 13.1 0.1 0.17 10.9 0.0 2.0 1 1 0 1 1 1 0 Zeta toxin ResIII PF04851.10 EEQ30578.1 - 0.04 13.7 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EEQ30578.1 - 0.042 13.0 0.0 0.09 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 EEQ30578.1 - 0.052 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Torsin Peptidase_M28 PF04389.12 EEQ30578.1 - 0.074 12.7 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M28 Parvo_NS1 PF01057.12 EEQ30578.1 - 0.079 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EEQ30578.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEQ30578.1 - 0.13 11.7 0.0 0.43 10.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.7 EEQ30578.1 - 0.14 11.7 0.0 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 EEQ30578.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Microtub_assoc PF07989.6 EEQ30579.1 - 9.4e-26 89.4 6.2 9.4e-26 89.4 4.3 11.6 8 4 4 13 13 13 2 Microtubule associated TMF_DNA_bd PF12329.3 EEQ30579.1 - 8.1e-10 38.3 17.6 8.1e-10 38.3 12.2 16.0 6 4 9 15 15 15 3 TATA element modulatory factor 1 DNA binding PACT_coil_coil PF10495.4 EEQ30579.1 - 1.9e-09 37.2 1.8 7.8e-09 35.3 1.3 2.2 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 EEQ30579.1 - 0.0014 18.4 16.2 0.0014 18.4 11.3 11.3 2 2 7 10 10 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UXS1_N PF11803.3 EEQ30579.1 - 0.57 9.9 5.2 7.5 6.3 0.5 4.6 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal Viral_Rep PF02407.11 EEQ30579.1 - 1.9 8.5 14.6 0.23 11.4 0.1 4.5 4 0 0 4 4 4 0 Putative viral replication protein SGT1 PF07093.6 EEQ30580.1 - 2.4e-137 458.8 29.2 1.6e-135 452.8 20.3 2.0 1 1 0 1 1 1 1 SGT1 protein Minor_tail_Z PF06763.6 EEQ30580.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) DUF1007 PF06226.8 EEQ30580.1 - 0.38 10.4 1.7 0.74 9.5 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1007) AMP-binding PF00501.23 EEQ30581.1 - 2.1e-39 135.1 0.0 2.5e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ30581.1 - 1.4e-06 29.1 0.0 3.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EEQ30582.1 - 1.9e-42 145.1 0.0 2.7e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ30582.1 - 0.13 13.2 0.0 0.3 12.0 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Gly-zipper_Omp PF13488.1 EEQ30583.1 - 0.24 11.0 1.8 0.47 10.1 1.3 1.4 1 0 0 1 1 1 0 Glycine zipper AMMECR1 PF01871.12 EEQ30584.1 - 8.5e-39 132.4 0.0 2.1e-38 131.1 0.0 1.7 2 0 0 2 2 2 1 AMMECR1 Mucin PF01456.12 EEQ30584.1 - 0.011 15.5 2.8 0.017 14.9 1.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_S64 PF08192.6 EEQ30584.1 - 0.92 7.7 3.6 1.2 7.3 2.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF605 PF04652.11 EEQ30584.1 - 6.2 6.1 12.6 8.6 5.6 8.7 1.1 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EEQ30586.1 - 1.5e-69 234.0 0.0 2.6e-69 233.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30586.1 - 1.7e-28 99.3 0.0 2.4e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ30586.1 - 5e-07 28.9 0.0 9.9e-07 27.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ30586.1 - 0.00026 20.8 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ30586.1 - 0.0011 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEQ30586.1 - 0.041 13.2 0.0 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF1744 PF08490.7 EEQ30587.1 - 2.3e-141 470.9 0.2 3.4e-141 470.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EEQ30587.1 - 3.4e-67 226.6 1.1 3.4e-67 226.6 0.7 2.6 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EEQ30587.1 - 4.9e-24 84.9 0.0 4.1e-23 81.8 0.1 2.1 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EEQ30587.1 - 2.5e-10 40.2 0.1 7.6e-10 38.6 0.1 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EEQ30587.1 - 1e-05 25.3 0.1 4.3e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.3 EEQ30588.1 - 2.9e-35 120.4 0.1 6.5e-35 119.3 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) Nop PF01798.13 EEQ30590.1 - 8.1e-60 200.4 0.0 1.6e-59 199.4 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEQ30590.1 - 1.1e-25 89.1 0.2 2.5e-25 88.0 0.2 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EEQ30590.1 - 9.1e-21 73.7 0.1 9.1e-21 73.7 0.1 3.3 3 1 0 3 3 3 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 EEQ30590.1 - 0.33 10.8 14.8 0.62 9.9 10.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 EEQ30590.1 - 0.49 10.1 7.3 0.85 9.3 5.0 1.5 1 0 0 1 1 1 0 DDHD domain RP-C_C PF11800.3 EEQ30590.1 - 2 8.0 11.1 33 4.1 0.0 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region RR_TM4-6 PF06459.7 EEQ30590.1 - 5.3 6.8 20.4 9.7 5.9 14.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cpn60_TCP1 PF00118.19 EEQ30591.1 - 4e-149 497.3 1.3 4.6e-149 497.1 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.13 EEQ30592.1 - 1.6e-55 187.2 0.9 6.5e-54 182.0 0.6 2.1 1 1 0 1 1 1 1 MOZ/SAS family RRM_1 PF00076.17 EEQ30593.1 - 7.3e-15 54.3 0.0 1.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ30593.1 - 1.9e-10 40.5 0.0 3.6e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IER PF05760.7 EEQ30593.1 - 0.00044 20.2 0.2 0.00044 20.2 0.2 2.5 2 1 0 2 2 2 1 Immediate early response protein (IER) RRM_5 PF13893.1 EEQ30593.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) His_Phos_1 PF00300.17 EEQ30593.1 - 0.051 13.6 1.1 0.14 12.2 0.7 1.8 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) AA_permease_2 PF13520.1 EEQ30594.1 - 5.3e-45 153.7 37.8 5e-32 110.9 11.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EEQ30594.1 - 2e-12 46.2 33.5 1.7e-07 29.9 13.9 2.1 1 1 1 2 2 2 2 Amino acid permease Sec23_trunk PF04811.10 EEQ30595.1 - 2.9e-40 138.1 0.0 3.4e-39 134.6 0.0 2.1 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEQ30595.1 - 1.1e-23 82.6 0.0 1.9e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EEQ30595.1 - 3.7e-18 65.8 0.0 2.9e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEQ30595.1 - 5.6e-16 57.8 5.9 1.1e-15 56.8 4.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEQ30595.1 - 8.9e-08 31.7 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Fe-ADH PF00465.14 EEQ30595.1 - 0.12 11.0 0.1 0.22 10.1 0.1 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Bys1 PF04681.7 EEQ30596.1 - 8.9e-07 28.7 0.3 1.1e-06 28.4 0.2 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thaumatin PF00314.12 EEQ30596.1 - 3.1e-05 23.5 0.8 0.04 13.3 0.0 2.2 1 1 1 2 2 2 2 Thaumatin family ABC_tran PF00005.22 EEQ30597.1 - 1.6e-49 167.6 0.1 1.3e-25 90.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EEQ30597.1 - 8.2e-47 159.0 34.9 3.9e-27 94.7 9.6 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 EEQ30597.1 - 4.1e-17 63.0 0.6 2.3e-05 24.5 0.1 4.3 3 1 1 4 4 4 3 AAA domain AAA_15 PF13175.1 EEQ30597.1 - 2.8e-10 39.8 0.0 0.051 12.6 0.0 4.1 4 0 0 4 4 4 3 AAA ATPase domain SMC_N PF02463.14 EEQ30597.1 - 1.2e-08 34.4 0.7 0.026 13.7 0.1 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EEQ30597.1 - 4.1e-08 32.5 0.6 0.003 16.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEQ30597.1 - 1.1e-07 32.3 2.0 0.00081 19.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ30597.1 - 7.2e-07 28.7 2.2 0.039 13.3 0.1 3.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EEQ30597.1 - 1.3e-06 28.5 0.2 0.04 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 EEQ30597.1 - 5.4e-06 26.0 1.6 0.065 13.0 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_17 PF13207.1 EEQ30597.1 - 5.5e-06 27.1 0.1 0.088 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ30597.1 - 6.5e-06 25.5 2.5 0.068 12.7 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EEQ30597.1 - 7.9e-06 26.0 0.8 0.13 12.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EEQ30597.1 - 1.2e-05 25.1 0.3 0.0046 16.6 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 EEQ30597.1 - 1.9e-05 24.3 1.3 0.017 14.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 EEQ30597.1 - 0.00074 19.7 0.6 1.6 8.9 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEQ30597.1 - 0.0011 18.9 2.0 0.68 9.8 0.6 2.3 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EEQ30597.1 - 0.0018 18.0 0.7 0.6 9.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EEQ30597.1 - 0.0018 17.7 3.6 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EEQ30597.1 - 0.0019 17.9 0.0 2.8 7.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EEQ30597.1 - 0.0023 17.0 0.9 0.076 12.0 0.1 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EEQ30597.1 - 0.003 16.4 0.5 1 8.2 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein SbcCD_C PF13558.1 EEQ30597.1 - 0.0032 17.3 0.2 4.2 7.3 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EEQ30597.1 - 0.0036 17.7 1.1 1.4 9.3 0.1 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EEQ30597.1 - 0.0048 16.3 6.4 0.53 9.6 1.2 2.4 2 0 0 2 2 2 2 AAA-like domain UPF0079 PF02367.12 EEQ30597.1 - 0.0059 16.2 1.5 0.73 9.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EEQ30597.1 - 0.0067 16.7 0.7 2.5 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EEQ30597.1 - 0.0075 15.8 0.6 3.2 7.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEQ30597.1 - 0.011 14.8 0.9 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.20 EEQ30597.1 - 0.014 14.8 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EEQ30597.1 - 0.023 14.8 0.3 2 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.7 EEQ30597.1 - 0.028 13.7 1.3 4.2 6.5 0.3 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_24 PF13479.1 EEQ30597.1 - 0.032 13.8 0.5 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEQ30597.1 - 0.033 14.0 1.4 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEQ30597.1 - 0.039 13.3 0.5 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.4 EEQ30597.1 - 0.043 13.3 0.8 6.2 6.3 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PDR_assoc PF08370.6 EEQ30597.1 - 0.062 12.8 0.1 0.21 11.1 0.1 1.9 1 0 0 1 1 1 0 Plant PDR ABC transporter associated FtsK_SpoIIIE PF01580.13 EEQ30597.1 - 0.18 11.2 1.8 2.9 7.3 0.3 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_35 PF14516.1 EEQ30597.1 - 0.22 10.1 0.1 4.4 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 EEQ30597.1 - 0.28 10.8 2.0 26 4.4 0.0 2.8 3 0 0 3 3 3 0 NTPase PRK PF00485.13 EEQ30597.1 - 0.29 10.6 1.4 11 5.5 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 EEQ30597.1 - 0.36 10.7 3.1 2.4 8.1 0.3 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EEQ30597.1 - 0.39 10.2 0.9 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.4 EEQ30597.1 - 1.3 7.9 1.4 11 4.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Phosphoprotein PF00922.12 EEQ30598.1 - 0.14 11.3 0.2 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Fungal_trans_2 PF11951.3 EEQ30599.1 - 2.3e-68 230.5 0.1 3.1e-68 230.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ30599.1 - 1.2e-09 37.9 10.0 2.1e-09 37.1 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EEQ30599.1 - 1.5 8.7 9.9 5.9 6.9 6.9 2.1 1 0 0 1 1 1 0 AT hook motif ESR1_C PF12743.2 EEQ30601.1 - 0.0034 16.8 0.4 0.0056 16.2 0.3 1.3 1 0 0 1 1 1 1 Oestrogen-type nuclear receptor final C-terminal DUF2434 PF10361.4 EEQ30602.1 - 2.8e-123 410.7 7.9 3.6e-123 410.3 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF202 PF02656.10 EEQ30602.1 - 7.2 6.9 7.8 2 8.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Gti1_Pac2 PF09729.4 EEQ30603.1 - 1.3e-50 171.5 1.2 1.4e-49 168.2 0.8 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family tRNA-synt_2 PF00152.15 EEQ30604.1 - 1.7e-48 165.1 0.0 6.7e-48 163.1 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ30604.1 - 8.8e-08 31.9 0.0 2.1e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 EEQ30604.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like CPSF100_C PF13299.1 EEQ30606.1 - 2.9e-42 144.6 0.1 2.9e-42 144.6 0.1 2.5 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EEQ30606.1 - 4.9e-28 97.5 0.0 1.5e-27 96.0 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EEQ30606.1 - 0.0036 17.0 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EEQ30606.1 - 0.043 13.4 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF1664 PF07889.7 EEQ30608.1 - 0.0036 17.0 1.4 0.07 12.9 0.4 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) MIS13 PF08202.6 EEQ30608.1 - 0.033 13.2 0.2 0.039 13.0 0.2 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Apolipoprotein PF01442.13 EEQ30608.1 - 0.045 13.2 0.3 0.06 12.8 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EEQ30608.1 - 0.16 12.3 6.0 0.18 12.2 2.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Cytochrom_B562 PF07361.6 EEQ30608.1 - 2.6 8.5 6.3 2.6 8.4 2.0 2.0 1 1 1 2 2 2 0 Cytochrome b562 Frag1 PF10277.4 EEQ30609.1 - 4.3e-42 144.0 7.3 4.3e-42 144.0 5.0 2.3 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.6 EEQ30610.1 - 6.6e-20 70.6 2.7 5.7e-19 67.6 0.9 2.8 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EEQ30610.1 - 3.1e-05 24.2 4.1 0.15 12.7 0.3 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ30610.1 - 0.0014 17.7 0.6 0.0025 16.9 0.4 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EEQ30610.1 - 0.0034 16.3 0.1 0.0056 15.6 0.1 1.5 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 EEQ30610.1 - 0.075 12.6 0.4 0.44 10.2 0.1 2.2 1 1 1 2 2 2 0 TPR repeat RF-1 PF00472.15 EEQ30611.1 - 3.9e-15 55.6 0.4 5.8e-15 55.0 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 EEQ30611.1 - 0.002 18.1 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein RRM_1 PF00076.17 EEQ30612.1 - 1.1e-09 37.7 0.0 2.5e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ30612.1 - 2e-07 30.8 0.0 3.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ30612.1 - 0.0039 17.0 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.12 EEQ30613.1 - 4.3e-24 84.3 2.1 5.5e-24 83.9 1.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 EEQ30613.1 - 0.032 14.3 0.2 0.043 13.9 0.2 1.3 1 0 0 1 1 1 0 Prolamin-like Pet191_N PF10203.4 EEQ30613.1 - 0.14 12.1 0.7 0.36 10.9 0.5 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EEQ30613.1 - 0.47 10.4 2.2 3.7 7.5 1.4 2.3 1 1 0 1 1 1 0 CHCH domain SYS1 PF09801.4 EEQ30614.1 - 2.7e-52 176.6 7.6 3.1e-52 176.4 5.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 EEQ30614.1 - 0.0074 15.9 2.9 0.0074 15.9 2.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF485 COG5 PF10392.4 EEQ30616.1 - 6.2e-38 129.7 1.5 2.9e-37 127.5 0.0 2.6 3 0 0 3 3 3 1 Golgi transport complex subunit 5 MutS_V PF00488.16 EEQ30620.1 - 5.9e-95 317.1 0.0 9.5e-95 316.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEQ30620.1 - 2.4e-38 131.9 0.3 4.7e-38 131.0 0.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EEQ30620.1 - 1.4e-22 80.2 0.1 5.3e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EEQ30620.1 - 4.4e-19 68.4 0.5 1.4e-18 66.7 0.4 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 EEQ30620.1 - 6.9e-16 58.2 0.0 4e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 MutS domain I Gpi1 PF05024.10 EEQ30621.1 - 3.2e-62 209.5 9.2 5.4e-62 208.8 6.4 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DNA_pol_A_exo1 PF01612.15 EEQ30623.1 - 1.9e-41 141.4 0.4 3.1e-41 140.7 0.3 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EEQ30623.1 - 4.2e-22 78.2 1.7 4.2e-22 78.2 1.1 2.7 3 1 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.18 EEQ30623.1 - 2.2e-11 43.3 0.6 6.2e-11 41.8 0.1 2.1 2 0 0 2 2 2 1 HRDC domain RasGAP PF00616.14 EEQ30624.1 - 1e-53 181.9 0.3 3.3e-53 180.2 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EEQ30624.1 - 2.6e-32 111.4 5.8 2.6e-32 111.4 4.0 2.7 3 0 0 3 3 3 1 RasGAP C-terminus DUF1647 PF07801.6 EEQ30624.1 - 0.073 12.5 1.7 0.13 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) CRAL_TRIO PF00650.15 EEQ30625.1 - 8.3e-38 129.3 0.0 1.1e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEQ30625.1 - 3.2e-08 33.5 0.4 3.2e-08 33.5 0.3 2.6 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEQ30625.1 - 1.7e-05 24.7 0.0 3.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 EEQ30626.1 - 7.5e-23 81.1 7.1 3e-22 79.1 5.0 1.9 1 1 0 1 1 1 1 Kinetochore protein Mis14 like Acetyltransf_1 PF00583.19 EEQ30629.1 - 1.2e-18 66.9 0.0 1.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ30629.1 - 5.3e-12 45.7 0.0 9.7e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ30629.1 - 9.8e-12 44.4 0.0 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ30629.1 - 3.8e-11 43.1 0.0 4.8e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEQ30629.1 - 2.3e-09 37.5 0.0 3.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ30629.1 - 1.3e-08 34.8 0.0 2.8e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ30629.1 - 3.1e-06 27.0 0.1 8.3e-06 25.6 0.0 1.8 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEQ30629.1 - 0.00012 22.0 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ30629.1 - 0.00094 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 EEQ30629.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase LCAT PF02450.10 EEQ30630.1 - 8.2e-93 311.4 0.0 1e-92 311.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EEQ30630.1 - 0.0032 17.3 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ30630.1 - 0.0049 16.6 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EEQ30630.1 - 0.0071 15.6 0.1 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) PAP2 PF01569.16 EEQ30631.1 - 1.1e-06 28.3 4.8 1.1e-06 28.3 3.3 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EEQ30631.1 - 1.3 8.4 13.2 0.72 9.3 1.1 2.7 2 1 1 3 3 3 0 PAP2 superfamily Sugar_tr PF00083.19 EEQ30632.1 - 3.6e-32 111.5 24.1 1.4e-31 109.5 16.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ30632.1 - 2.5e-30 105.3 28.4 2.5e-30 105.3 19.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.20 EEQ30633.1 - 1.7e-21 76.5 0.0 2.7e-21 75.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30633.1 - 2.1e-07 30.2 0.0 3.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ30633.1 - 0.0034 16.4 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1768 PF08719.6 EEQ30635.1 - 3.3e-49 166.6 0.0 3.7e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1628 PF07790.6 EEQ30636.1 - 0.01 16.5 1.5 0.018 15.7 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) Cut8_N PF14482.1 EEQ30636.1 - 0.015 15.2 0.5 0.022 14.7 0.4 1.4 1 1 0 1 1 1 0 Cut8 proteasome-binding domain Bacteriocin_IId PF09221.5 EEQ30636.1 - 0.024 14.5 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 Bacteriocin class IId cyclical uberolysin-like TMEMspv1-c74-12 PF11044.3 EEQ30636.1 - 0.051 13.1 0.3 0.12 11.9 0.2 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Ibs_toxin PF13956.1 EEQ30636.1 - 0.065 13.0 2.5 0.065 13.0 1.7 1.7 2 0 0 2 2 2 0 Toxin Ibs, type I toxin-antitoxin system PhoQ_Sensor PF08918.5 EEQ30636.1 - 0.12 11.9 1.5 0.33 10.4 1.0 1.6 1 1 0 1 1 1 0 PhoQ Sensor DUF4307 PF14155.1 EEQ30636.1 - 0.16 11.7 3.0 6.3 6.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) Peptidase_M28 PF04389.12 EEQ30640.1 - 1.5e-28 99.7 0.0 2.2e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 EEQ30640.1 - 0.0077 15.4 0.0 0.036 13.2 0.0 2.1 2 0 0 2 2 2 1 Nicastrin Peptidase_M20 PF01546.23 EEQ30640.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Glyco_hydro_81 PF03639.8 EEQ30641.1 - 5.8e-192 639.3 1.4 7.3e-192 639.0 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 CsbD PF05532.7 EEQ30641.1 - 0.031 13.9 0.5 0.25 11.0 0.1 2.3 2 0 0 2 2 2 0 CsbD-like Utp14 PF04615.8 EEQ30642.1 - 1.1e-210 701.6 60.3 1.1e-210 701.6 41.8 2.1 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 EEQ30643.1 - 1.6e-11 43.7 0.2 2.1e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Cauli_VI PF01693.11 EEQ30643.1 - 0.071 13.1 0.3 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 Caulimovirus viroplasmin HECT PF00632.20 EEQ30644.1 - 3.8e-78 262.8 0.0 8.9e-78 261.6 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EEQ30644.1 - 0.0094 15.5 0.6 0.0094 15.5 0.4 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif RRM_1 PF00076.17 EEQ30645.1 - 4.1e-75 247.3 5.4 1.2e-22 79.2 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ30645.1 - 9.1e-50 166.5 0.5 1e-14 54.2 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ30645.1 - 2.1e-41 139.5 0.1 1.9e-10 40.4 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EEQ30645.1 - 3.7e-28 97.0 1.1 1.2e-27 95.3 0.2 2.4 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EEQ30645.1 - 6.6e-05 22.5 1.9 2.5 7.8 0.0 3.7 3 0 0 3 3 3 2 Limkain b1 Nup35_RRM_2 PF14605.1 EEQ30645.1 - 0.00014 21.5 0.1 16 5.3 0.0 4.9 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EEQ30645.1 - 0.00041 20.5 0.0 2.7 8.2 0.0 3.6 3 0 0 3 3 3 2 Cobalamin biosynthesis central region RRM_3 PF08777.6 EEQ30645.1 - 0.014 15.2 15.7 0.096 12.5 0.6 4.8 4 1 1 5 5 5 0 RNA binding motif TC1 PF15063.1 EEQ30645.1 - 0.03 13.8 0.3 12 5.5 0.0 3.3 3 0 0 3 3 3 0 Thyroid cancer protein 1 OB_RNB PF08206.6 EEQ30645.1 - 0.064 12.7 2.1 10 5.7 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Fe-ADH PF00465.14 EEQ30646.1 - 1.8e-69 234.1 2.0 2.2e-69 233.8 1.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEQ30646.1 - 1.3e-22 80.3 0.4 1.9e-22 79.8 0.3 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EEQ30646.1 - 0.00011 21.2 0.1 0.26 10.1 0.0 2.2 2 0 0 2 2 2 2 3-dehydroquinate synthase Peripla_BP_6 PF13458.1 EEQ30646.1 - 0.0021 17.4 0.1 0.0038 16.6 0.1 1.5 2 0 0 2 2 2 1 Periplasmic binding protein DAO PF01266.19 EEQ30647.1 - 1.7e-53 181.8 0.0 1.9e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ30647.1 - 1.3e-05 25.0 0.5 2.8e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EEQ30647.1 - 3e-05 23.3 0.1 4.2e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEQ30647.1 - 0.00017 21.7 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ30647.1 - 0.0043 16.9 0.0 0.0085 15.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEQ30647.1 - 0.0069 15.4 0.2 0.015 14.3 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EEQ30647.1 - 0.029 14.7 0.4 0.063 13.6 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ30647.1 - 0.03 13.3 0.3 0.1 11.6 0.1 1.8 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 EEQ30647.1 - 0.035 13.7 0.4 0.059 13.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EEQ30647.1 - 0.037 13.9 0.6 0.09 12.6 0.4 1.7 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_9 PF13454.1 EEQ30647.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EEQ30647.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EEQ30647.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EEQ30647.1 - 0.16 11.4 0.4 0.25 10.7 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 EEQ30647.1 - 0.26 10.0 3.0 0.41 9.4 2.1 1.2 1 0 0 1 1 1 0 FAD binding domain Vps52 PF04129.7 EEQ30648.1 - 2.4e-119 399.2 0.5 3.2e-119 398.7 0.3 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EEQ30648.1 - 3.6e-05 22.1 1.0 5.2e-05 21.6 0.7 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 eIF-5a PF01287.15 EEQ30649.1 - 1.6e-25 88.8 2.0 2.3e-25 88.3 1.4 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EEQ30649.1 - 3.1e-05 23.5 0.7 3.1e-05 23.5 0.5 1.9 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 EEQ30649.1 - 0.0074 16.1 0.2 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain RRN7 PF11781.3 EEQ30650.1 - 3.4e-07 29.6 4.3 6e-07 28.8 3.0 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Ribosomal_L40e PF01020.12 EEQ30651.1 - 1.3e-30 104.6 10.6 1.9e-30 104.2 7.4 1.2 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 EEQ30651.1 - 3.6e-19 67.9 0.0 4.8e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEQ30651.1 - 3.3e-10 39.4 0.0 4.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EEQ30651.1 - 0.02 14.5 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Telomere stability and silencing Glu_cyclase_2 PF05096.7 EEQ30651.1 - 0.076 12.0 0.0 0.085 11.8 0.0 1.0 1 0 0 1 1 1 0 Glutamine cyclotransferase Yip1 PF04893.12 EEQ30652.1 - 1e-14 54.4 16.4 1.8e-14 53.5 11.3 1.5 1 1 0 1 1 1 1 Yip1 domain TMEM154 PF15102.1 EEQ30652.1 - 0.043 13.5 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family RabGAP-TBC PF00566.13 EEQ30653.1 - 2.5e-27 95.7 0.1 3.6e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ICAT PF06384.6 EEQ30653.1 - 0.079 12.7 0.1 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT MMS1_N PF10433.4 EEQ30654.1 - 4.3e-110 368.2 0.0 8.5e-108 360.6 0.0 3.4 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EEQ30654.1 - 2.2e-07 30.3 0.0 1.1e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 CPSF A subunit region GTP_EFTU PF00009.22 EEQ30655.1 - 9.3e-33 113.2 0.0 6.7e-32 110.4 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EEQ30655.1 - 6.2e-20 71.1 0.1 1.7e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EEQ30655.1 - 2e-11 43.8 0.7 1.2e-09 38.0 0.0 3.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ30655.1 - 2.7e-06 27.3 0.0 1.1e-05 25.3 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EEQ30655.1 - 0.00075 19.0 0.0 0.0028 17.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EEQ30655.1 - 0.0026 18.2 0.9 0.0093 16.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 EEQ30655.1 - 0.0055 16.2 0.0 0.016 14.7 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Rhodanese PF00581.15 EEQ30656.1 - 4.7e-12 46.2 0.0 8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF4267 PF14087.1 EEQ30656.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) p450 PF00067.17 EEQ30657.1 - 6.7e-53 179.8 0.0 1.1e-52 179.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EEQ30659.1 - 9e-26 90.7 0.4 1.2e-25 90.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ30659.1 - 4.6e-14 52.7 0.1 5.8e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ30659.1 - 1e-11 44.8 0.1 1.5e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EEQ30659.1 - 2.1e-06 27.1 0.0 3.9e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EEQ30659.1 - 0.00028 20.9 0.2 0.00058 19.9 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EEQ30659.1 - 0.0016 18.1 0.1 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EEQ30659.1 - 0.0032 16.9 0.1 0.0053 16.2 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEQ30659.1 - 0.0032 16.4 0.1 0.0045 15.9 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DASH_Duo1 PF08651.5 EEQ30659.1 - 0.014 14.9 0.5 2.4 7.8 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Duo1 RmlD_sub_bind PF04321.12 EEQ30659.1 - 0.095 11.5 0.1 0.21 10.4 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_2 PF00891.13 EEQ30660.1 - 8.9e-09 34.8 0.0 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase adh_short PF00106.20 EEQ30661.1 - 4.7e-21 75.4 0.0 6.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ30661.1 - 5.9e-14 52.4 0.0 8.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ30661.1 - 8.2e-08 32.1 0.0 2.1e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEQ30661.1 - 1.9e-05 24.7 0.0 4.7e-05 23.4 0.0 1.8 1 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EEQ30661.1 - 2.7e-05 23.7 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEQ30661.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EEQ30661.1 - 0.0067 16.1 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyoxalase_2 PF12681.2 EEQ30662.1 - 3.6e-11 43.6 0.0 4.4e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EEQ30662.1 - 0.00025 21.0 0.0 0.0012 18.8 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Radial_spoke PF04712.7 EEQ30662.1 - 0.13 10.9 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein PPR PF01535.15 EEQ30664.1 - 6.3e-20 69.6 2.9 0.00022 20.9 0.0 8.6 8 0 0 8 8 8 4 PPR repeat PPR_2 PF13041.1 EEQ30664.1 - 9.4e-20 70.3 2.3 1.1e-07 31.6 0.0 7.2 3 2 5 8 8 8 5 PPR repeat family PPR_3 PF13812.1 EEQ30664.1 - 1.5e-18 65.4 0.9 0.0014 18.7 0.0 9.2 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EEQ30664.1 - 6.5e-07 28.7 0.0 3.3 7.2 0.0 5.7 6 0 0 6 6 6 3 PPR repeat TPR_15 PF13429.1 EEQ30664.1 - 0.019 14.0 1.8 2.7 6.9 0.1 4.0 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ30664.1 - 0.039 14.6 0.0 20 6.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MCM PF00493.18 EEQ30665.1 - 1.9e-129 431.2 0.2 2.7e-129 430.7 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEQ30665.1 - 7.9e-17 61.8 0.0 2.4e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ30665.1 - 9.5e-07 28.1 0.0 1.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEQ30665.1 - 0.0032 17.0 0.0 0.0087 15.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEQ30665.1 - 0.075 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Spo7 PF03907.8 EEQ30666.1 - 2.1e-63 213.7 2.0 6.1e-63 212.2 1.4 1.6 1 1 0 1 1 1 1 Spo7-like protein YL1 PF05764.8 EEQ30666.1 - 0.36 10.4 5.9 0.68 9.5 4.1 1.4 1 1 0 1 1 1 0 YL1 nuclear protein Abhydrolase_6 PF12697.2 EEQ30667.1 - 1.2e-28 100.5 4.2 7.8e-28 97.8 2.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ30667.1 - 1.6e-15 57.3 0.0 6.3e-13 48.8 0.0 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ30667.1 - 1.9e-14 53.6 0.0 2e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EEQ30667.1 - 6.7e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 EEQ30667.1 - 0.00054 19.1 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EEQ30667.1 - 0.00058 18.8 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.15 EEQ30667.1 - 0.00078 19.7 0.3 0.016 15.4 0.3 2.7 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_3 PF07859.8 EEQ30667.1 - 0.002 17.7 0.0 0.0072 15.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EEQ30667.1 - 0.0023 17.3 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 EEQ30667.1 - 0.0039 16.8 0.0 0.07 12.7 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.3 EEQ30667.1 - 0.0071 16.1 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EEQ30667.1 - 0.0082 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Lipase_3 PF01764.20 EEQ30667.1 - 0.0083 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 EEQ30667.1 - 0.017 14.5 0.0 2.8 7.3 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EEQ30667.1 - 0.068 12.3 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family TatD_DNase PF01026.16 EEQ30668.1 - 1.9e-37 128.8 0.0 2.8e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase TPP_enzyme_N PF02776.13 EEQ30669.1 - 1.5e-30 105.9 0.4 5.2e-27 94.4 0.1 3.4 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEQ30669.1 - 2.2e-20 72.7 0.0 4.1e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEQ30669.1 - 4e-19 68.7 0.0 1.5e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF4248 PF14053.1 EEQ30669.1 - 0.066 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Chitin_synth_2 PF03142.10 EEQ30670.1 - 2.1e-230 765.6 0.0 3.1e-230 765.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EEQ30670.1 - 2.9e-67 227.2 0.0 1.4e-66 225.0 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EEQ30670.1 - 2.8e-22 78.3 0.0 1.3e-12 47.3 0.0 2.5 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EEQ30670.1 - 7.9e-16 58.3 4.7 7.9e-16 58.3 3.3 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ30670.1 - 1.5e-15 57.6 0.0 1.9e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 EEQ30670.1 - 2.8e-15 55.8 0.6 7.4e-15 54.4 0.3 1.8 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 EEQ30670.1 - 7e-07 28.6 0.0 5.5e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEQ30670.1 - 0.00086 19.0 0.0 0.088 12.4 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 EEQ30672.1 - 4.1e-254 843.8 0.4 6e-254 843.3 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EEQ30672.1 - 2e-178 594.6 0.0 2.7e-178 594.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EEQ30672.1 - 1.6e-20 72.6 0.0 2e-13 49.9 0.0 3.3 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EEQ30672.1 - 8.8e-17 60.6 2.0 2.8e-16 59.0 1.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EEQ30672.1 - 1.7e-15 57.2 6.0 4.4e-15 55.9 4.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ30672.1 - 2.7e-14 53.5 0.1 3.9e-11 43.1 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EEQ30672.1 - 0.00013 21.6 0.0 0.0084 15.8 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EEQ30672.1 - 0.0011 18.2 0.3 0.012 14.9 0.2 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 21 AAA_16 PF13191.1 EEQ30672.1 - 0.0046 16.9 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EEQ30672.1 - 0.077 12.1 0.0 0.41 9.8 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEQ30672.1 - 0.1 12.7 0.1 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain KH_1 PF00013.24 EEQ30673.1 - 4e-25 87.2 0.0 1.3e-06 27.9 0.1 6.1 6 0 0 6 6 6 5 KH domain KH_3 PF13014.1 EEQ30673.1 - 8.1e-21 73.2 2.1 0.00064 19.3 0.0 6.4 6 0 0 6 6 6 4 KH domain HATPase_c_5 PF14501.1 EEQ30673.1 - 0.069 12.8 0.3 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 GHKL domain SelP_N PF04592.9 EEQ30673.1 - 0.25 10.7 15.8 0.42 9.9 10.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EEQ30673.1 - 0.55 9.1 5.5 0.95 8.4 3.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 EEQ30673.1 - 1.2 7.2 22.8 1.7 6.7 15.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 EEQ30673.1 - 5.4 4.5 13.6 8.1 4.0 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HAD_2 PF13419.1 EEQ30674.1 - 1.2e-29 103.7 0.3 1.5e-29 103.4 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ30674.1 - 6.3e-05 22.6 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEQ30674.1 - 0.0012 19.3 0.0 0.0018 18.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Dynactin PF12455.3 EEQ30676.1 - 4.1e-98 327.6 2.0 4.1e-98 327.6 1.4 3.3 2 1 1 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 EEQ30676.1 - 2.4e-19 68.7 0.1 4.4e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Beta_elim_lyase PF01212.16 EEQ30677.1 - 7e-42 143.5 0.1 4.1e-30 104.9 0.0 2.1 2 0 0 2 2 2 2 Beta-eliminating lyase Corona_NS2A PF05213.7 EEQ30677.1 - 0.062 12.6 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein Sulf_transp PF04143.9 EEQ30677.1 - 0.32 11.0 2.9 0.97 9.5 2.0 1.8 1 0 0 1 1 1 0 Sulphur transport Solute_trans_a PF03619.11 EEQ30679.1 - 9.1e-68 228.5 0.3 9.1e-68 228.5 0.2 1.5 2 0 0 2 2 2 1 Organic solute transporter Ostalpha PAS_11 PF14598.1 EEQ30680.1 - 0.021 14.8 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain GTP_EFTU PF00009.22 EEQ30681.1 - 3.4e-62 209.2 0.1 4.7e-62 208.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEQ30681.1 - 1.5e-34 118.1 0.0 6.6e-34 116.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EEQ30681.1 - 4.2e-21 74.6 0.0 1.2e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEQ30681.1 - 3.2e-13 49.5 0.0 3.7e-12 46.1 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EEQ30681.1 - 3.9e-12 45.8 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EEQ30681.1 - 1.5e-05 24.9 0.0 3.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_6 PF14259.1 EEQ30682.1 - 4.2e-10 39.4 0.0 3.9e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ30682.1 - 2.1e-08 33.6 0.1 7.6e-06 25.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EEQ30682.1 - 3.4e-08 33.4 0.3 6.8e-08 32.5 0.2 1.5 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 EEQ30682.1 - 1.8e-06 27.7 0.0 3.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ30682.1 - 1.6e-05 24.5 0.0 8.8e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EEQ30682.1 - 9.7e-05 21.9 0.9 0.00016 21.2 0.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF737 PF05300.6 EEQ30682.1 - 0.11 12.4 12.8 0.26 11.2 8.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Borrelia_P83 PF05262.6 EEQ30682.1 - 0.29 9.3 6.8 0.4 8.9 4.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ribosomal_L6e PF01159.14 EEQ30682.1 - 2 8.7 5.7 5.2 7.3 4.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L6e HNH_2 PF13391.1 EEQ30683.1 - 2.9e-17 62.1 0.0 5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.11 EEQ30684.1 - 2.5e-37 128.4 15.7 5.3e-37 127.3 10.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ30684.1 - 1.1e-10 40.7 15.7 3.2e-10 39.1 10.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EEQ30684.1 - 5.1e-08 31.7 5.9 5.1e-08 31.7 4.1 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein NfeD PF01957.13 EEQ30684.1 - 0.0089 16.1 7.0 0.2 11.7 0.3 3.4 3 0 0 3 3 3 2 NfeD-like C-terminal, partner-binding DUF663 PF04950.7 EEQ30686.1 - 6.4e-91 304.3 0.0 6.4e-91 304.3 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EEQ30686.1 - 7.3e-27 92.7 0.0 1.6e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EEQ30686.1 - 1.3e-07 31.2 0.0 1.3e-05 24.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EEQ30686.1 - 2.8e-05 24.2 0.0 7.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ30686.1 - 0.00012 22.1 0.0 0.00038 20.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EEQ30686.1 - 0.00014 22.0 0.0 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EEQ30686.1 - 0.0006 19.5 0.3 0.0014 18.3 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EEQ30686.1 - 0.00074 19.4 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EEQ30686.1 - 0.00089 18.7 0.0 0.0038 16.7 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EEQ30686.1 - 0.0011 19.7 0.0 0.0011 19.7 0.0 4.4 4 1 1 5 5 2 1 AAA domain Miro PF08477.8 EEQ30686.1 - 0.0014 19.0 0.0 0.0048 17.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein NTPase_1 PF03266.10 EEQ30686.1 - 0.0025 17.5 0.3 0.0053 16.4 0.2 1.5 1 0 0 1 1 1 1 NTPase AAA_24 PF13479.1 EEQ30686.1 - 0.0043 16.6 0.2 0.011 15.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EEQ30686.1 - 0.0045 15.8 0.0 0.0087 14.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 EEQ30686.1 - 0.0068 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase cobW PF02492.14 EEQ30686.1 - 0.0075 15.7 0.1 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EEQ30686.1 - 0.0084 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EEQ30686.1 - 0.0088 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEQ30686.1 - 0.01 15.2 0.0 0.058 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EEQ30686.1 - 0.014 15.6 0.0 0.014 15.6 0.0 3.3 4 0 0 4 4 2 0 AAA domain AAA_33 PF13671.1 EEQ30686.1 - 0.019 14.8 0.1 0.019 14.8 0.1 2.4 3 0 0 3 3 1 0 AAA domain ABC_tran PF00005.22 EEQ30686.1 - 0.025 14.8 2.1 0.027 14.7 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_5 PF07728.9 EEQ30686.1 - 0.039 13.6 0.2 0.15 11.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EEQ30686.1 - 0.04 13.6 0.7 0.079 12.7 0.1 1.8 2 0 0 2 2 1 0 Part of AAA domain DUF258 PF03193.11 EEQ30686.1 - 0.054 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 EEQ30686.1 - 0.11 12.0 4.2 0.78 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EEQ30686.1 - 0.13 11.7 0.1 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.12 EEQ30686.1 - 0.14 11.6 0.1 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Aminotran_1_2 PF00155.16 EEQ30687.1 - 7.3e-41 140.3 0.0 8.8e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEQ30687.1 - 0.085 11.9 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Dendrin PF15498.1 EEQ30688.1 - 0.0009 17.8 4.2 0.0017 16.9 2.9 1.4 1 0 0 1 1 1 1 Nephrin and CD2AP-binding protein, Dendrin Med3 PF11593.3 EEQ30688.1 - 0.16 11.1 4.3 0.24 10.5 3.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2051 PF09738.4 EEQ30688.1 - 0.33 10.2 4.3 0.59 9.3 2.9 1.4 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) MSP1_C PF07462.6 EEQ30688.1 - 0.77 8.0 5.2 1.2 7.4 3.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Dicty_REP PF05086.7 EEQ30688.1 - 0.78 7.4 4.8 0.99 7.0 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF515 PF04415.7 EEQ30688.1 - 1.1 7.4 8.4 1.6 6.8 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SSP160 PF06933.6 EEQ30688.1 - 1.4 6.7 18.4 2 6.2 12.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EEQ30688.1 - 1.6 8.4 20.2 0.34 10.6 11.2 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF1989 PF09347.5 EEQ30690.1 - 6.2e-55 185.1 0.0 7.6e-55 184.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Abhydrolase_6 PF12697.2 EEQ30691.1 - 5.2e-25 88.6 0.0 6.6e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ30691.1 - 7.9e-09 35.4 0.2 2.9e-08 33.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ30691.1 - 8.9e-09 35.2 0.0 4.1e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEQ30691.1 - 0.00022 20.7 0.0 0.33 10.3 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EEQ30691.1 - 0.014 15.2 0.0 0.053 13.3 0.0 2.0 1 0 0 1 1 1 0 Putative lysophospholipase NADH_Oxid_Nqo15 PF11497.3 EEQ30691.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 EHN PF06441.7 EEQ30691.1 - 0.085 12.7 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Epoxide hydrolase N terminus DUF3425 PF11905.3 EEQ30692.1 - 1.4e-22 80.0 1.1 1.5e-22 79.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EEQ30692.1 - 0.0018 18.1 9.2 0.003 17.4 6.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor HCR PF07111.7 EEQ30692.1 - 0.02 12.8 2.3 0.028 12.4 1.6 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) Peptidase_S31 PF05578.7 EEQ30693.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 BCDHK_Adom3 PF10436.4 EEQ30694.1 - 3.3e-43 147.0 0.0 4.4e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EEQ30694.1 - 5.4e-15 55.0 0.0 3e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EEQ30694.1 - 0.0045 16.7 0.0 0.018 14.8 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain MFS_1 PF07690.11 EEQ30695.1 - 7e-21 74.3 39.8 4e-19 68.5 27.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ30695.1 - 0.017 13.3 21.2 0.04 12.1 14.5 1.7 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 EEQ30695.1 - 2.7 7.9 8.4 0.13 12.2 0.2 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF1349 PF07081.6 EEQ30696.1 - 2e-25 89.2 0.0 2.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Ras PF00071.17 EEQ30697.1 - 1.3e-52 177.4 0.0 1.5e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ30697.1 - 1.5e-16 60.9 0.0 2.4e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ30697.1 - 4.3e-06 26.0 0.0 6.1e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.16 EEQ30698.1 - 1.4e-84 283.6 0.1 1.8e-84 283.3 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EEQ30698.1 - 0.00077 19.7 0.1 0.0017 18.5 0.1 1.6 1 0 0 1 1 1 1 UPF0489 domain ketoacyl-synt PF00109.21 EEQ30699.1 - 1.2e-57 195.3 0.8 4.4e-57 193.4 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEQ30699.1 - 1.5e-34 118.3 0.7 2.7e-34 117.5 0.5 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EEQ30699.1 - 3.6e-05 22.8 0.5 0.0003 19.8 0.1 2.4 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEQ30699.1 - 0.065 12.6 5.5 0.12 11.8 0.3 3.1 3 1 0 3 3 3 0 Thiolase, C-terminal domain Lactamase_B_2 PF12706.2 EEQ30700.1 - 3.4e-14 52.8 4.4 3.1e-13 49.6 3.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EEQ30700.1 - 0.0008 19.1 2.4 0.0083 15.8 1.6 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain JSRP PF15312.1 EEQ30701.1 - 0.13 12.2 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein CorA PF01544.13 EEQ30701.1 - 0.16 10.9 2.0 0.28 10.1 1.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein p450 PF00067.17 EEQ30702.1 - 1.4e-46 158.9 0.0 2.5e-46 158.2 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Vint PF14623.1 EEQ30703.1 - 2.4e-57 192.9 0.0 7e-57 191.4 0.0 1.8 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.1 EEQ30703.1 - 5.1e-31 106.6 0.0 8.7e-31 105.8 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 EEQ30703.1 - 1.1e-17 64.6 0.0 2.2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EEQ30703.1 - 5.3e-16 58.8 0.0 2.5e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.1 EEQ30703.1 - 9.4e-13 48.1 0.0 1.5e-10 41.0 0.0 3.0 3 0 0 3 3 3 1 von Willebrand factor type A domain Hint_2 PF13403.1 EEQ30703.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Hint domain ABC_membrane PF00664.18 EEQ30704.1 - 7e-94 314.2 26.2 2.5e-48 164.9 4.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ30704.1 - 1.4e-67 226.2 0.0 9.5e-34 116.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ30704.1 - 2.6e-13 49.7 0.8 0.00018 20.7 0.2 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ30704.1 - 3.3e-12 46.9 0.0 0.069 13.1 0.0 4.4 3 1 1 4 4 4 3 AAA domain AAA_16 PF13191.1 EEQ30704.1 - 2.6e-08 34.0 2.8 0.00011 22.2 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EEQ30704.1 - 1.5e-07 32.2 0.0 0.0037 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EEQ30704.1 - 1.8e-07 30.1 0.3 0.024 13.2 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EEQ30704.1 - 2.6e-07 30.0 4.1 0.00035 20.0 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EEQ30704.1 - 1.2e-06 28.6 0.4 0.037 14.1 0.0 3.5 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEQ30704.1 - 1.7e-06 27.3 0.0 0.046 12.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EEQ30704.1 - 8.1e-05 22.9 0.1 0.37 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EEQ30704.1 - 9e-05 22.1 0.5 1 8.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EEQ30704.1 - 0.00011 21.3 0.2 0.049 12.7 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_25 PF13481.1 EEQ30704.1 - 0.00026 20.4 0.4 0.94 8.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEQ30704.1 - 0.00044 20.1 0.0 1.5 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EEQ30704.1 - 0.00063 19.4 0.4 0.41 10.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EEQ30704.1 - 0.00074 19.7 0.9 0.15 12.2 0.1 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEQ30704.1 - 0.0011 18.7 0.1 2.9 7.7 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain SRP54 PF00448.17 EEQ30704.1 - 0.0022 17.4 0.1 2.2 7.6 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EEQ30704.1 - 0.0023 17.8 0.0 5.4 6.9 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 EEQ30704.1 - 0.0048 17.2 0.7 0.65 10.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEQ30704.1 - 0.0068 15.8 0.2 5.7 6.2 0.0 3.2 3 0 0 3 3 3 0 AAA-like domain AAA_28 PF13521.1 EEQ30704.1 - 0.0079 16.1 1.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 EEQ30704.1 - 0.0079 14.9 0.0 1.6 7.3 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit MobB PF03205.9 EEQ30704.1 - 0.012 15.3 0.0 7.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EEQ30704.1 - 0.022 14.6 7.3 0.32 10.9 0.4 3.7 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 EEQ30704.1 - 0.025 13.2 0.1 0.23 10.1 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ACR_tran PF00873.14 EEQ30704.1 - 0.03 11.7 0.3 0.052 10.9 0.2 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family PRK PF00485.13 EEQ30704.1 - 0.036 13.6 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 EEQ30704.1 - 0.043 13.7 0.1 17 5.4 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 EEQ30704.1 - 0.064 12.6 0.0 0.49 9.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_2 PF07724.9 EEQ30704.1 - 0.064 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATP-synt_ab PF00006.20 EEQ30704.1 - 0.1 12.0 0.7 1 8.8 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EEQ30704.1 - 0.11 12.6 0.1 6.8 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 EEQ30704.1 - 0.12 11.4 0.0 5.1 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 EEQ30704.1 - 0.16 10.8 1.1 6.8 5.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EEQ30704.1 - 0.23 10.5 1.4 9.4 5.2 0.1 2.3 2 0 0 2 2 2 0 KaiC CAP59_mtransfer PF11735.3 EEQ30705.1 - 3.7e-76 255.5 0.0 5.4e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 BAF1_ABF1 PF04684.8 EEQ30710.1 - 0.28 9.9 6.3 0.39 9.5 4.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GST_N PF02798.15 EEQ30711.1 - 1.6e-13 50.6 0.0 4.7e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEQ30711.1 - 4.9e-12 45.8 0.0 8.9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ30711.1 - 3.6e-10 39.6 0.0 7.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ30711.1 - 1.7e-09 37.4 0.0 3.7e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ30711.1 - 5.8e-06 26.6 0.0 9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ30711.1 - 0.00018 21.3 0.0 0.00044 20.0 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain APH PF01636.18 EEQ30712.1 - 4.2e-05 23.4 0.3 0.0002 21.1 0.3 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ30712.1 - 0.0014 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEQ30712.1 - 0.024 14.0 0.0 0.051 12.9 0.0 1.5 2 0 0 2 2 2 0 RIO1 family DUF1762 PF08574.5 EEQ30714.1 - 4.9e-14 52.5 12.2 6.3e-14 52.1 7.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1762) RRM_1 PF00076.17 EEQ30715.1 - 4.3e-39 131.9 0.0 7.8e-12 44.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ30715.1 - 1e-37 127.9 0.0 1.3e-09 37.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ30715.1 - 4.6e-17 61.6 0.0 0.00024 20.8 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EEQ30715.1 - 7.3e-12 44.6 8.0 7.3e-12 44.6 5.6 2.9 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 EEQ30715.1 - 2.7e-05 23.9 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 EEQ30715.1 - 0.033 14.1 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain Nup35_RRM_2 PF14605.1 EEQ30715.1 - 0.19 11.5 0.0 54 3.6 0.0 3.3 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif YL1 PF05764.8 EEQ30716.1 - 2.5e-58 197.5 25.4 2.5e-58 197.5 17.6 1.7 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EEQ30716.1 - 1.1e-11 44.0 0.2 1.9e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain ATP-synt_E PF05680.7 EEQ30716.1 - 8.2 6.4 14.0 0.51 10.3 0.7 3.0 2 0 0 2 2 2 0 ATP synthase E chain PCNA_C PF02747.10 EEQ30717.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain tRNA-synt_2 PF00152.15 EEQ30718.1 - 1.9e-74 250.4 0.2 3.8e-74 249.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ30718.1 - 2.8e-07 30.2 0.0 5.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF818 PF05677.7 EEQ30719.1 - 0.54 8.9 3.6 0.48 9.0 1.6 1.5 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) PUF PF00806.14 EEQ30720.1 - 1.2e-28 96.9 0.0 1.2e-05 24.4 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EEQ30720.1 - 1e-10 41.1 0.0 2.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ30720.1 - 2.7e-07 30.3 0.0 5.9e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ30720.1 - 5.6e-06 26.2 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MT-A70 PF05063.9 EEQ30722.1 - 1.3e-23 83.4 0.0 1.8e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Peptidase_C12 PF01088.16 EEQ30723.1 - 4.5e-64 215.5 0.0 5.4e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DcpS_C PF11969.3 EEQ30724.1 - 1.7e-30 105.6 0.2 2.6e-30 105.0 0.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EEQ30724.1 - 6.2e-27 94.1 0.0 1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Alk_phosphatase PF00245.15 EEQ30725.1 - 1.6e-69 234.6 1.4 2.7e-69 233.8 1.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EEQ30725.1 - 2.9e-07 29.9 2.9 2.1e-06 27.1 1.9 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EEQ30725.1 - 4.8e-06 26.1 0.5 8.6e-06 25.2 0.3 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EEQ30725.1 - 0.0044 15.4 0.1 0.0085 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) RNase_H2_suC PF08615.6 EEQ30726.1 - 1.5e-26 92.8 0.0 2.4e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.19 EEQ30727.1 - 9.1e-28 97.6 0.0 1.3e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EEQ30727.1 - 0.022 14.2 0.0 0.056 12.9 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease Nop53 PF07767.6 EEQ30728.1 - 2e-106 356.2 36.7 2.9e-106 355.7 25.4 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Pal1 PF08316.6 EEQ30728.1 - 0.22 11.9 1.9 0.77 10.2 1.3 1.9 1 0 0 1 1 1 0 Pal1 cell morphology protein Myb_Cef PF11831.3 EEQ30729.1 - 1.7e-58 197.6 4.7 1.7e-58 197.6 3.2 3.4 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EEQ30729.1 - 6.5e-20 70.9 3.8 4.2e-09 36.3 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ30729.1 - 2.1e-19 69.3 6.0 7.9e-13 48.3 1.1 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain MOZ_SAS PF01853.13 EEQ30730.1 - 9e-80 266.3 0.0 1.4e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EEQ30730.1 - 6.3e-24 83.4 0.0 1.2e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF1918 PF08940.6 EEQ30730.1 - 0.0046 16.2 0.0 0.021 14.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1918) F1F0-ATPsyn_F PF10791.4 EEQ30732.1 - 6.6e-38 128.8 0.2 7.4e-38 128.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EEQ30732.1 - 0.00051 20.0 0.0 0.0006 19.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 EEQ30733.1 - 7.9e-32 109.1 1.0 1.3e-31 108.4 0.7 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Nipped-B_C PF12830.2 EEQ30734.1 - 2.8e-53 180.3 8.1 4.7e-52 176.3 0.8 4.0 3 1 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EEQ30734.1 - 8.2e-11 41.6 2.1 8.2e-11 41.6 1.5 3.1 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EEQ30734.1 - 0.00063 19.6 3.4 0.44 10.7 0.1 5.5 5 0 0 5 5 5 1 HEAT repeat Methyltransf_11 PF08241.7 EEQ30735.1 - 1.3e-16 60.8 0.1 7.8e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ30735.1 - 7.5e-15 55.0 0.1 7.8e-09 35.4 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ30735.1 - 6.3e-12 45.7 0.0 9.8e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ30735.1 - 6.5e-11 42.0 0.0 2.6e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ30735.1 - 2.9e-09 37.2 0.0 2.6e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ30735.1 - 6.3e-09 35.8 0.0 0.00015 21.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ30735.1 - 2.3e-08 33.4 0.0 0.003 16.7 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EEQ30735.1 - 3e-08 34.2 0.0 1.1e-06 29.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 EEQ30735.1 - 0.00035 19.9 0.0 0.0012 18.3 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW TehB PF03848.9 EEQ30735.1 - 0.00076 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 EEQ30735.1 - 0.0016 17.8 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain UPF0146 PF03686.8 EEQ30735.1 - 0.0033 17.2 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) FmrO PF07091.6 EEQ30735.1 - 0.0056 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.6 EEQ30735.1 - 0.0081 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 EEQ30735.1 - 0.0085 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EEQ30735.1 - 0.034 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 3HCDH_N PF02737.13 EEQ30735.1 - 0.046 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_2 PF00891.13 EEQ30735.1 - 0.12 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase TFIIS_C PF01096.13 EEQ30736.1 - 3e-15 55.5 2.2 3e-15 55.5 1.5 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEQ30736.1 - 1.2e-05 24.8 2.1 1.2e-05 24.8 1.4 2.6 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Ribosomal_S27e PF01667.12 EEQ30736.1 - 0.008 15.6 3.7 3 7.4 0.0 3.7 3 1 1 4 4 4 1 Ribosomal protein S27 NMD3 PF04981.8 EEQ30736.1 - 0.035 13.2 2.8 0.077 12.0 1.9 1.6 1 1 0 1 1 1 0 NMD3 family Zn-ribbon_8 PF09723.5 EEQ30736.1 - 0.13 12.2 6.7 1.2 9.1 0.1 3.2 3 1 0 3 3 3 0 Zinc ribbon domain DUF2072 PF09845.4 EEQ30736.1 - 0.19 11.6 3.8 2 8.3 0.0 2.3 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) OrfB_Zn_ribbon PF07282.6 EEQ30736.1 - 0.2 11.3 9.7 1.8 8.2 1.7 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain RRN7 PF11781.3 EEQ30736.1 - 0.47 9.9 9.6 1.3 8.6 0.3 3.9 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 Lar_restr_allev PF14354.1 EEQ30736.1 - 0.59 10.4 9.0 1.1e+02 3.1 6.3 3.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 EEQ30736.1 - 0.86 8.8 12.6 1.1 8.5 0.0 3.8 3 1 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EEQ30736.1 - 0.89 9.4 10.9 8.7 6.2 4.8 3.0 1 1 1 2 2 2 0 Double zinc ribbon RecR PF02132.10 EEQ30736.1 - 0.9 9.0 5.7 0.16 11.3 0.5 2.2 2 0 0 2 2 2 0 RecR protein ArfGap PF01412.13 EEQ30736.1 - 0.94 9.2 5.4 4.6 7.0 0.1 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf NOB1_Zn_bind PF08772.6 EEQ30736.1 - 1.7 8.5 4.9 11 5.9 0.2 2.8 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Zn_ribbon_recom PF13408.1 EEQ30736.1 - 1.8 8.8 11.0 4.5 7.6 0.8 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-CSL PF05207.8 EEQ30736.1 - 2.8 7.4 8.8 3.4 7.2 0.2 3.2 2 1 0 3 3 3 0 CSL zinc finger zinc_ribbon_2 PF13240.1 EEQ30736.1 - 3 7.4 11.9 5.7 6.5 0.7 3.8 3 1 0 3 3 3 0 zinc-ribbon domain zf-C4_Topoisom PF01396.14 EEQ30736.1 - 3.5 7.2 7.0 2.8 7.5 0.6 3.2 2 2 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Zn_Tnp_IS1595 PF12760.2 EEQ30736.1 - 4.6 7.1 8.3 1.5 8.6 1.2 2.8 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zf-RING_4 PF14570.1 EEQ30736.1 - 5.2 6.7 6.5 6.2 6.4 0.0 3.0 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain TF_Zn_Ribbon PF08271.7 EEQ30736.1 - 7 6.0 15.9 6.2 6.2 0.2 3.7 2 2 0 3 3 3 0 TFIIB zinc-binding HEAT_2 PF13646.1 EEQ30737.1 - 2.9e-38 130.0 7.0 1.1e-15 57.7 0.1 3.8 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 EEQ30737.1 - 3.7e-22 76.5 0.9 0.0027 18.0 0.0 6.4 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EEQ30737.1 - 5.3e-11 42.6 8.9 0.0033 17.8 0.0 5.8 3 2 3 6 6 6 4 HEAT-like repeat HEAT PF02985.17 EEQ30737.1 - 7.2e-08 31.8 2.1 0.42 10.8 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.18 EEQ30737.1 - 0.0059 16.3 0.0 4 7.4 0.0 3.2 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Imm16 PF15565.1 EEQ30737.1 - 0.037 13.8 0.8 0.68 9.8 0.3 2.7 4 0 0 4 4 4 0 Immunity protein 16 RuvA_C PF07499.8 EEQ30737.1 - 0.12 12.5 0.9 5 7.3 0.0 3.5 3 0 0 3 3 3 0 RuvA, C-terminal domain Pyr_redox_2 PF07992.9 EEQ30738.1 - 1.4e-17 64.2 0.0 2.5e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ30738.1 - 8.8e-11 42.0 0.0 1.4e-09 38.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EEQ30738.1 - 1.5e-05 23.9 0.1 5.2e-05 22.2 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EEQ30738.1 - 0.00018 20.7 0.1 0.00046 19.3 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EEQ30738.1 - 0.00022 20.8 0.2 0.0007 19.2 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EEQ30738.1 - 0.0016 18.5 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Myc_N PF01056.13 EEQ30738.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region EF-hand_4 PF12763.2 EEQ30738.1 - 0.23 11.2 1.1 2.8 7.7 0.0 2.9 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand CLTH PF10607.4 EEQ30739.1 - 1.5e-34 118.7 0.5 2.1e-34 118.3 0.4 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EEQ30739.1 - 5.1e-10 38.7 0.0 1.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 LisH PRK PF00485.13 EEQ30740.1 - 4.7e-52 176.3 0.0 6.2e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EEQ30740.1 - 4.6e-07 30.6 0.1 1.8e-06 28.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EEQ30740.1 - 2.3e-05 24.6 0.0 4.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ30740.1 - 0.00015 20.9 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.12 EEQ30740.1 - 0.0053 16.5 0.1 0.0099 15.7 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF87 CPT PF07931.7 EEQ30740.1 - 0.0064 16.1 0.0 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 EEQ30740.1 - 0.051 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EEQ30740.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EEQ30740.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EEQ30740.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NUC153 PF08159.7 EEQ30741.1 - 1.8e-13 49.8 7.7 8.6e-13 47.6 0.1 3.6 3 0 0 3 3 3 1 NUC153 domain DUF4148 PF13663.1 EEQ30741.1 - 0.041 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Npa1 PF11707.3 EEQ30742.1 - 3.5e-95 318.7 0.1 8.2e-95 317.5 0.1 1.7 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal MutS_III PF05192.13 EEQ30742.1 - 0.32 10.7 4.4 0.23 11.1 0.8 2.4 2 1 0 2 2 2 0 MutS domain III HA2 PF04408.18 EEQ30744.1 - 3.1e-29 101.0 0.1 5.9e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEQ30744.1 - 3.4e-24 84.8 0.0 5.2e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EEQ30745.1 - 3.6e-05 23.3 0.0 7.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EEQ30745.1 - 0.00015 20.7 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EEQ30745.1 - 0.0043 17.1 0.1 0.011 15.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ30745.1 - 0.0045 16.6 0.3 0.036 13.8 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EEQ30745.1 - 0.12 12.3 0.3 1.1 9.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EEQ30745.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EEQ30745.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC UPF0079 PF02367.12 EEQ30745.1 - 0.14 11.8 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EEQ30745.1 - 0.23 11.4 2.1 0.48 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain SUV3_C PF12513.3 EEQ30746.1 - 1e-15 56.8 0.0 2.1e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EEQ30746.1 - 8.9e-10 38.3 0.0 9.6e-09 34.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain TK PF00265.13 EEQ30746.1 - 0.16 11.5 0.0 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 Thymidine kinase Sec1 PF00995.18 EEQ30747.1 - 2.8e-128 429.0 0.0 3.2e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.18 EEQ30748.1 - 1.3e-06 28.1 0.2 2.7e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.20 EEQ30749.1 - 1.2e-13 51.2 0.0 1.7e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEQ30749.1 - 9.9e-08 31.8 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ30749.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEQ30749.1 - 0.0018 17.7 0.1 0.0049 16.3 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEQ30749.1 - 0.0026 17.8 0.1 0.0062 16.5 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding DUF4235 PF14019.1 EEQ30749.1 - 0.017 14.9 1.1 0.048 13.5 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) NmrA PF05368.8 EEQ30749.1 - 0.047 12.9 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 EEQ30749.1 - 0.099 12.4 0.6 0.35 10.6 0.4 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EEQ30750.1 - 8.4e-47 159.5 0.0 1e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EEQ30750.1 - 1.1e-26 92.5 0.2 1.9e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EEQ30750.1 - 4.6e-15 55.0 0.0 6.6e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EEQ30750.1 - 2.3e-12 47.1 0.0 3.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EEQ30750.1 - 9.9e-12 44.3 0.0 1.5e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EEQ30750.1 - 1.1e-11 44.1 0.0 1.3e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EEQ30750.1 - 3.1e-08 33.5 0.0 5.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEQ30750.1 - 6e-08 32.8 0.0 9.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEQ30750.1 - 4.4e-07 29.0 0.0 1.2e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein DAO PF01266.19 EEQ30750.1 - 0.00061 18.7 0.2 0.0022 16.9 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase adh_short_C2 PF13561.1 EEQ30750.1 - 0.0013 18.5 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EEQ30750.1 - 0.0017 17.6 0.0 0.0065 15.7 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EEQ30750.1 - 0.0024 17.3 0.1 0.0043 16.4 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 EEQ30750.1 - 0.0026 18.3 0.0 2.3 8.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain 3HCDH_N PF02737.13 EEQ30750.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EEQ30750.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EEQ30750.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 EEQ30751.1 - 5.3e-24 85.2 0.0 6.2e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEQ30751.1 - 2.3e-10 40.1 0.0 3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EEQ30751.1 - 2e-06 27.4 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ30751.1 - 0.0022 16.7 0.0 0.0029 16.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EEQ30751.1 - 0.0085 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase PAT1 PF09770.4 EEQ30752.1 - 1e-202 675.6 43.6 7e-101 338.8 0.0 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 AIG2 PF06094.7 EEQ30753.1 - 2e-11 44.2 0.0 2.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 AIG2-like family Glyco_transf_15 PF01793.11 EEQ30754.1 - 6.8e-143 475.5 4.5 8.3e-143 475.2 3.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.20 EEQ30755.1 - 2.8e-41 139.7 3.2 3.7e-41 139.3 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UMP1 PF05348.6 EEQ30756.1 - 1.9e-22 79.6 0.0 2.2e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF3608 PF12257.3 EEQ30758.1 - 4.5e-75 252.1 0.0 1.2e-74 250.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EEQ30758.1 - 2e-30 104.3 1.1 4e-30 103.3 0.8 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FNIP_N PF14636.1 EEQ30759.1 - 2.1e-27 96.1 0.1 2.1e-27 96.1 0.0 4.7 4 1 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EEQ30759.1 - 0.012 15.1 0.4 0.083 12.4 0.0 2.1 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain SNF2_N PF00176.18 EEQ30761.1 - 1.7e-43 148.5 0.0 2.9e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ30761.1 - 5.6e-08 32.5 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EEQ30761.1 - 0.0018 17.9 11.5 0.0046 16.6 8.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ30761.1 - 0.0064 16.1 13.4 0.016 14.8 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ30761.1 - 0.018 15.0 13.7 0.059 13.4 9.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ30761.1 - 0.58 9.8 13.1 1.7 8.3 9.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EEQ30762.1 - 1.8e-12 46.7 11.1 2.6e-07 30.1 0.0 4.6 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 EEQ30762.1 - 3.6e-11 43.4 21.2 0.0013 19.3 0.0 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ30762.1 - 7.9e-10 37.9 25.7 2e-05 24.1 0.0 6.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ30762.1 - 3.2e-09 36.5 16.3 0.012 15.5 2.0 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ30762.1 - 2.4e-07 30.0 6.7 0.022 14.5 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ30762.1 - 9e-07 28.2 17.9 1e-05 24.8 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ30762.1 - 8.3e-06 26.0 13.3 0.97 9.8 1.2 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ30762.1 - 4.2e-05 23.8 22.1 0.036 14.7 0.1 8.0 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ30762.1 - 4.7e-05 22.8 7.9 0.21 11.4 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ30762.1 - 0.0011 19.2 12.6 2.5 8.7 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ30762.1 - 0.0053 16.8 5.4 67 4.0 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ30762.1 - 0.17 11.7 16.8 0.18 11.6 0.0 5.6 6 2 0 6 6 6 0 Tetratricopeptide repeat Pmp3 PF01679.12 EEQ30763.1 - 1.9e-19 69.1 7.0 2.5e-19 68.7 4.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pneumo_att_G PF05539.6 EEQ30763.1 - 0.51 9.6 2.4 0.6 9.4 1.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Totivirus_coat PF05518.6 EEQ30763.1 - 2.2 5.9 5.3 2.5 5.8 3.7 1.0 1 0 0 1 1 1 0 Totivirus coat protein SH3_9 PF14604.1 EEQ30764.1 - 4.2e-08 32.6 0.2 9.8e-08 31.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ30764.1 - 0.00044 19.5 0.1 0.00081 18.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 EEQ30764.1 - 0.0069 15.6 1.8 0.012 14.9 1.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Cytomega_TRL10 PF06084.6 EEQ30764.1 - 0.062 13.0 0.0 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Rax2 PF12768.2 EEQ30764.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Fungal_trans PF04082.13 EEQ30768.1 - 2e-22 79.3 0.1 4.9e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ30768.1 - 4.3e-05 23.3 7.4 9.6e-05 22.2 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_Ca_ex PF01699.19 EEQ30769.1 - 4.1e-40 136.6 24.6 1.9e-21 76.1 9.3 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Bestrophin PF01062.16 EEQ30769.1 - 0.13 11.2 3.6 2.5 6.9 0.1 2.2 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel GHMP_kinases_N PF00288.21 EEQ30770.1 - 3.4e-15 55.8 0.5 9.3e-15 54.4 0.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEQ30770.1 - 2.5e-08 34.0 0.0 6.7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal MCM PF00493.18 EEQ30771.1 - 4.3e-132 439.9 0.1 7e-132 439.2 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEQ30771.1 - 8.3e-17 61.8 2.5 8.9e-17 61.7 0.0 2.3 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ30771.1 - 7.7e-05 21.9 0.0 0.00037 19.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ30771.1 - 0.0043 16.7 0.0 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEQ30771.1 - 0.0083 15.7 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEQ30771.1 - 0.014 14.8 0.0 0.036 13.5 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain RRN3 PF05327.6 EEQ30771.1 - 2.8 5.9 7.2 4.6 5.2 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EamA PF00892.15 EEQ30772.1 - 1.2e-07 31.7 4.9 1.5e-07 31.5 3.4 1.1 1 0 0 1 1 1 1 EamA-like transporter family DUF914 PF06027.7 EEQ30772.1 - 0.00018 20.4 0.0 0.00021 20.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EEQ30772.1 - 0.0035 17.5 4.9 0.0062 16.7 3.4 1.4 1 1 0 1 1 1 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 EEQ30772.1 - 0.026 14.3 4.9 0.031 14.1 3.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 Glyco_hydro_59 PF02057.10 EEQ30772.1 - 0.11 10.5 0.5 0.12 10.3 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 TPT PF03151.11 EEQ30772.1 - 0.75 9.4 6.1 1 9.0 4.2 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family Voltage_CLC PF00654.15 EEQ30773.1 - 1.4e-88 297.2 23.9 1.4e-88 297.2 16.6 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EEQ30773.1 - 4.1e-12 45.6 0.0 0.0001 22.0 0.0 2.4 2 0 0 2 2 2 2 CBS domain VPEP PF07589.6 EEQ30773.1 - 5.9 6.9 7.5 0.93 9.4 0.9 3.1 2 0 0 2 2 2 0 PEP-CTERM motif CBFD_NFYB_HMF PF00808.18 EEQ30774.1 - 2.2e-12 46.8 0.0 4.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Rieske PF00355.21 EEQ30775.1 - 5.2e-17 61.1 0.0 9.1e-17 60.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EEQ30775.1 - 1.3e-11 44.5 7.2 2.7e-10 40.3 1.3 2.4 2 0 0 2 2 2 2 Ubiquinol cytochrome reductase transmembrane region She9_MDM33 PF05546.6 EEQ30776.1 - 9e-88 293.2 7.4 1.2e-87 292.8 5.1 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family MBD_C PF14048.1 EEQ30776.1 - 0.01 16.3 0.1 0.026 15.0 0.1 1.8 1 0 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 PsbH PF00737.15 EEQ30776.1 - 0.015 14.8 0.9 0.027 14.0 0.6 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein E2_bind PF08825.5 EEQ30776.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 E2 binding domain DUF1110 PF06533.7 EEQ30776.1 - 0.72 9.6 6.5 4.4 7.0 2.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1110) TMF_DNA_bd PF12329.3 EEQ30776.1 - 1.8 8.4 7.9 2.6 7.9 0.5 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Aminotran_1_2 PF00155.16 EEQ30777.1 - 2e-33 115.8 0.0 2.9e-23 82.4 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEQ30777.1 - 0.009 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.13 EEQ30778.1 - 2.8e-13 49.3 1.0 6.3e-13 48.2 0.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ30778.1 - 1.2e-08 34.7 11.3 1.2e-08 34.7 7.8 3.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EEQ30779.1 - 5.3e-75 252.1 0.1 1.3e-74 250.9 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ30779.1 - 3e-42 145.0 0.8 5.1e-42 144.3 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEQ30779.1 - 1.6e-32 111.8 0.7 1.6e-32 111.8 0.5 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EEQ30779.1 - 6.8e-13 48.6 0.1 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EEQ30779.1 - 1.1e-05 24.5 0.0 2.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EEQ30779.1 - 0.021 14.5 0.2 0.41 10.3 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Trp_DMAT PF11991.3 EEQ30780.1 - 4.4e-82 276.1 0.0 5.3e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Orexin PF02072.10 EEQ30780.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Prepro-orexin DUF4060 PF13269.1 EEQ30780.1 - 0.027 14.4 0.1 6.4 6.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4060) FAD_binding_3 PF01494.14 EEQ30781.1 - 1.9e-14 53.4 3.3 3.2e-08 33.0 0.5 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEQ30781.1 - 0.00053 18.9 0.4 0.011 14.6 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ30781.1 - 0.0062 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DDE_Tnp_1_6 PF13751.1 EEQ30781.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Thi4 PF01946.12 EEQ30781.1 - 0.039 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lactamase_B PF00753.22 EEQ30782.1 - 1.2e-19 70.7 0.4 1.9e-19 70.1 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEQ30782.1 - 0.0009 18.8 0.1 0.0013 18.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Peptidase_M10_C PF08548.6 EEQ30782.1 - 0.12 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal Fungal_trans PF04082.13 EEQ30783.1 - 1.6e-08 33.7 0.1 2.5e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ30783.1 - 7e-08 32.2 6.9 1.4e-07 31.3 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_75 PF07335.6 EEQ30784.1 - 4.9e-41 140.2 0.1 6.4e-41 139.8 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 PNPOx_C PF10590.4 EEQ30785.1 - 2.6e-21 74.8 4.1 1.5e-20 72.3 2.0 2.5 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EEQ30785.1 - 1.4e-10 41.0 0.0 8e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EEQ30785.1 - 0.011 16.0 0.0 0.044 14.0 0.0 1.9 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.1 EEQ30786.1 - 2.9e-40 136.0 11.3 2.2e-09 37.1 0.0 13.7 11 3 4 15 15 15 9 PPR repeat family PPR_3 PF13812.1 EEQ30786.1 - 2.5e-31 105.2 21.2 9.9e-05 22.3 0.0 14.1 15 0 0 15 15 15 6 Pentatricopeptide repeat domain PPR PF01535.15 EEQ30786.1 - 7.4e-27 91.4 10.9 0.00041 20.1 0.0 13.2 13 0 0 13 13 13 6 PPR repeat PPR_1 PF12854.2 EEQ30786.1 - 1.4e-19 69.2 0.4 7.2e-07 28.5 0.0 9.7 10 0 0 10 10 10 3 PPR repeat RPM2 PF08579.6 EEQ30786.1 - 4e-07 30.1 0.1 4.8e-05 23.4 0.0 3.6 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 EEQ30786.1 - 0.0011 17.9 0.1 1.2 7.9 0.0 3.5 3 0 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway RecX PF02631.11 EEQ30786.1 - 0.049 13.8 1.2 22 5.2 0.3 3.2 3 0 0 3 3 3 0 RecX family DUF2972 PF11186.3 EEQ30786.1 - 0.099 12.5 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Peptidase_S64 PF08192.6 EEQ30788.1 - 8.4e-06 24.4 0.1 0.00014 20.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S64 Trypsin_2 PF13365.1 EEQ30788.1 - 0.019 14.9 0.0 0.089 12.7 0.0 2.1 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S46 PF10459.4 EEQ30788.1 - 0.24 9.7 0.0 0.4 9.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase S46 Pkinase PF00069.20 EEQ30789.1 - 8.2e-26 90.6 0.0 4.4e-25 88.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30789.1 - 1e-07 31.2 0.2 0.022 13.8 0.0 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ30789.1 - 0.046 12.6 0.0 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EEQ30789.1 - 0.067 12.2 0.1 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box PF00646.28 EEQ30790.1 - 3.5e-05 23.3 0.4 0.00011 21.7 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ30790.1 - 0.00052 19.6 0.0 0.0018 17.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like Peptidase_S41 PF03572.13 EEQ30791.1 - 1.7e-08 34.0 0.0 4.5e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Ribosomal_L7Ae PF01248.21 EEQ30792.1 - 3.1e-25 87.4 0.0 3.7e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EEQ30792.1 - 0.00018 21.4 0.1 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF221 PF02714.10 EEQ30793.1 - 1e-113 379.5 23.1 2.8e-111 371.4 11.6 3.0 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEQ30793.1 - 1.3e-44 151.5 0.8 6.3e-44 149.3 0.6 2.3 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EEQ30793.1 - 2.3e-32 110.7 0.1 4.5e-32 109.7 0.1 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EEQ30793.1 - 1.5e-21 76.6 0.2 4.6e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) DUF3323 PF11796.3 EEQ30794.1 - 0.083 12.1 1.2 0.22 10.8 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function N-terminus (DUF3323) EHN PF06441.7 EEQ30796.1 - 1.2e-37 128.2 1.2 1.4e-36 124.7 0.1 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EEQ30796.1 - 1.2e-14 54.7 1.5 1e-13 51.6 1.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ30796.1 - 2.6e-12 46.7 0.1 1.6e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ank_2 PF12796.2 EEQ30798.1 - 1.5e-62 207.9 8.2 4.3e-16 59.0 0.1 5.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ30798.1 - 9.5e-45 148.2 10.1 1.5e-08 34.0 0.0 8.9 8 1 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 EEQ30798.1 - 8.9e-38 127.4 7.8 1.6e-07 31.3 0.0 7.1 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ30798.1 - 5.4e-34 115.9 7.1 2.4e-06 27.9 0.0 7.7 4 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ30798.1 - 3.5e-31 104.1 8.5 1.8e-06 27.5 0.0 7.8 8 1 0 8 8 8 6 Ankyrin repeat Shigella_OspC PF06128.6 EEQ30798.1 - 0.015 14.8 0.0 2.1 7.7 0.0 3.2 3 1 0 3 3 3 0 Shigella flexneri OspC protein ASXH PF13919.1 EEQ30798.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Asx homology domain Pyridox_oxase_2 PF12766.2 EEQ30801.1 - 1.2e-24 86.5 0.0 2e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LRR_9 PF14580.1 EEQ30802.1 - 4.5e-52 176.1 0.0 6.3e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EEQ30802.1 - 1.3e-10 40.6 8.5 1.4e-05 24.5 0.6 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ30802.1 - 3.5e-09 36.2 13.8 2.7e-06 27.0 2.4 3.2 1 1 3 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EEQ30802.1 - 0.00044 19.9 5.7 5.6 7.4 0.0 5.3 6 0 0 6 6 6 1 Leucine Rich Repeat HTH_38 PF13936.1 EEQ30802.1 - 0.011 15.2 0.2 0.026 14.0 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain LRR_7 PF13504.1 EEQ30802.1 - 0.49 10.8 5.4 1.1e+02 3.7 0.0 4.4 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EEQ30802.1 - 0.53 10.5 2.7 32 5.0 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat GDA1_CD39 PF01150.12 EEQ30803.1 - 4.5e-108 361.5 0.0 6e-108 361.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.16 EEQ30804.1 - 2e-17 62.8 0.0 4.4e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.10 EEQ30805.1 - 1.5e-82 276.4 0.0 4.3e-82 275.0 0.0 1.6 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.24 EEQ30806.1 - 3e-37 127.7 0.0 5.9e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ30806.1 - 9.5e-20 70.2 0.0 2.7e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EEQ30806.1 - 3.6e-19 68.0 0.0 7.4e-19 67.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EEQ30806.1 - 0.0039 17.0 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.27 EEQ30807.1 - 1.7e-24 84.7 6.2 3.9e-05 23.3 0.1 7.3 7 2 0 7 7 7 5 WD domain, G-beta repeat DUF3423 PF11903.3 EEQ30807.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3423) Fungal_trans_2 PF11951.3 EEQ30808.1 - 5.9e-09 34.9 3.4 1.8e-07 30.1 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF305 PF03713.8 EEQ30808.1 - 0.53 10.1 14.8 1.3 8.8 5.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF305) MFS_1 PF07690.11 EEQ30809.1 - 2e-42 145.2 44.0 2e-42 145.2 30.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ30809.1 - 2.4e-06 26.0 15.8 3.5e-06 25.5 10.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.23 EEQ30810.1 - 5.9e-09 35.6 0.0 7.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EEQ30810.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EEQ30810.1 - 0.11 11.9 0.2 1.7 8.0 0.1 2.6 1 1 0 1 1 1 0 Peptidase C26 DUF775 PF05603.7 EEQ30811.1 - 3e-66 222.8 0.1 3.3e-66 222.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EEQ30812.1 - 1.1e-07 31.5 0.1 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 EEQ30813.1 - 1.9e-36 125.2 0.0 2.1e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 EEQ30814.1 - 4.7e-121 404.0 0.0 5.2e-121 403.8 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 EEQ30815.1 - 1.8e-15 56.4 0.0 5.1e-15 55.0 0.0 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain MAT1 PF06391.8 EEQ30815.1 - 0.015 14.9 4.9 0.02 14.4 3.4 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 NMU PF02070.10 EEQ30815.1 - 0.06 12.8 0.8 0.95 9.0 0.0 2.5 2 0 0 2 2 2 0 Neuromedin U UPF0086 PF01868.11 EEQ30816.1 - 1.1e-26 92.3 0.0 1.8e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Copper-bind PF00127.15 EEQ30818.1 - 0.0015 18.7 0.2 0.0036 17.5 0.2 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EEQ30818.1 - 0.032 14.1 0.0 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Cupredoxin-like domain DUF1325 PF07039.6 EEQ30818.1 - 0.061 12.9 0.2 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 SGF29 tudor-like domain DUF605 PF04652.11 EEQ30818.1 - 0.34 10.2 3.6 0.45 9.8 2.5 1.1 1 0 0 1 1 1 0 Vta1 like Tmemb_cc2 PF10267.4 EEQ30818.1 - 2.7 6.4 5.1 3.3 6.1 3.6 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ank_2 PF12796.2 EEQ30819.1 - 2.5e-58 194.3 16.2 1.1e-13 51.3 0.1 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ30819.1 - 6.4e-44 147.5 11.0 2.1e-09 37.6 0.0 8.2 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ30819.1 - 2e-42 142.2 6.2 4.9e-11 42.5 0.0 6.4 5 1 0 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EEQ30819.1 - 1e-39 132.3 8.7 7.1e-05 22.4 0.0 10.4 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.1 EEQ30819.1 - 2.9e-27 92.0 1.1 0.0023 18.0 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat Trehalase_Ca-bi PF07492.6 EEQ30819.1 - 0.02 14.1 1.1 46 3.4 0.1 4.6 5 0 0 5 5 5 0 Neutral trehalase Ca2+ binding domain MFS_1 PF07690.11 EEQ30820.1 - 8.5e-25 87.2 23.7 8.5e-25 87.2 16.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phos_pyr_kin PF08543.7 EEQ30820.1 - 0.04 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase NfeD PF01957.13 EEQ30820.1 - 4.8 7.3 14.0 1.2 9.2 0.0 4.0 2 2 2 4 4 4 0 NfeD-like C-terminal, partner-binding FYVE_2 PF02318.11 EEQ30822.1 - 0.0024 17.7 22.5 0.17 11.7 1.9 3.3 3 0 0 3 3 3 3 FYVE-type zinc finger zf-C3HC4 PF00097.20 EEQ30822.1 - 0.0071 15.9 38.3 0.22 11.1 4.5 3.4 3 0 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) YadA_stalk PF05662.9 EEQ30822.1 - 0.23 11.2 1.3 0.39 10.5 0.9 1.4 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin zf-C3HC4_2 PF13923.1 EEQ30822.1 - 0.65 10.0 38.3 0.68 10.0 5.2 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Siva PF05458.7 EEQ30822.1 - 1.3 8.6 21.5 0.31 10.5 1.1 3.2 3 0 0 3 3 3 0 Cd27 binding protein (Siva) zf-RING_5 PF14634.1 EEQ30822.1 - 8.2 6.2 38.2 6.1 6.6 4.6 3.6 3 0 0 3 3 3 0 zinc-RING finger domain Ank_2 PF12796.2 EEQ30823.1 - 4.1e-47 158.4 3.2 6.9e-16 58.3 0.0 4.4 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ30823.1 - 1.5e-39 131.8 7.9 4.5e-09 35.6 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EEQ30823.1 - 9.9e-38 127.8 2.4 1.8e-10 40.9 0.0 6.5 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ30823.1 - 1.9e-27 94.6 8.6 9.7e-09 35.2 0.0 7.3 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ30823.1 - 1.3e-26 90.0 6.1 3.2e-06 26.8 0.0 8.1 9 0 0 9 9 9 5 Ankyrin repeat Ank_2 PF12796.2 EEQ30824.1 - 4.2e-14 52.6 0.1 1.9e-12 47.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) NACHT PF05729.7 EEQ30824.1 - 6.2e-11 42.2 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Ank PF00023.25 EEQ30824.1 - 9.7e-11 40.9 0.0 4.2e-05 23.1 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEQ30824.1 - 2.8e-09 36.8 0.2 2.6e-05 24.3 0.1 3.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ30824.1 - 4.2e-07 30.3 0.0 5.5e-06 26.7 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ30824.1 - 2.1e-06 27.4 0.0 0.1 12.9 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat AAA_19 PF13245.1 EEQ30824.1 - 0.0048 16.6 0.1 0.026 14.2 0.0 2.3 3 0 0 3 3 3 1 Part of AAA domain KAP_NTPase PF07693.9 EEQ30824.1 - 0.0052 15.8 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Mg_chelatase PF01078.16 EEQ30824.1 - 0.0074 15.4 0.0 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EEQ30824.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein HlyIII PF03006.15 EEQ30825.1 - 6.1e-45 153.3 16.5 7.5e-45 153.0 11.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_S8 PF00082.17 EEQ30826.1 - 1.7e-18 66.8 0.0 2.8e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Cofilin_ADF PF00241.15 EEQ30828.1 - 2.6e-08 33.8 0.0 3.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 EEQ30829.1 - 3.1e-31 107.7 0.0 5.4e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EEQ30830.1 - 1.4e-59 200.0 0.2 1.7e-59 199.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ30830.1 - 7.6e-19 68.3 0.0 1.1e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ30830.1 - 1.5e-07 30.8 0.0 1.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ30830.1 - 1.2e-06 28.0 0.1 6.7e-06 25.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEQ30830.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EEQ30830.1 - 0.0022 17.9 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2075 PF09848.4 EEQ30830.1 - 0.049 12.5 0.1 1.3 7.9 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 EEQ30830.1 - 0.05 12.7 0.0 0.089 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EEQ30830.1 - 0.055 12.5 0.1 0.076 12.1 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 EEQ30830.1 - 0.11 11.9 0.9 1.2 8.5 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF4630 PF15443.1 EEQ30831.1 - 0.029 14.2 0.5 0.034 13.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) adh_short PF00106.20 EEQ30832.1 - 1.2e-34 119.6 0.0 1.5e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ30832.1 - 1.5e-15 57.6 0.0 1.9e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ30832.1 - 8.9e-13 48.2 0.0 1.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEQ30832.1 - 1.3e-05 24.8 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EEQ30832.1 - 0.0023 17.4 0.1 0.0075 15.7 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEQ30832.1 - 0.0047 15.8 0.1 0.01 14.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Lin0512_fam PF09585.5 EEQ30832.1 - 0.07 12.6 0.2 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) CENP-B_dimeris PF09026.5 EEQ30833.1 - 0.23 11.7 3.6 0.32 11.2 2.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GATA PF00320.22 EEQ30835.1 - 4.5e-30 102.7 18.1 5e-16 57.7 3.5 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EEQ30835.1 - 1.3e-07 30.8 3.0 0.0034 16.6 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EEQ30835.1 - 0.0032 17.3 1.6 0.51 10.3 0.1 2.9 2 0 0 2 2 2 1 Zinc ribbon domain DZR PF12773.2 EEQ30835.1 - 0.012 15.4 11.1 0.16 11.7 0.3 3.1 2 1 0 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 EEQ30835.1 - 0.096 12.2 0.3 0.096 12.2 0.2 2.7 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 EEQ30835.1 - 0.37 10.0 10.6 1.1 8.5 1.6 3.0 2 2 0 2 2 2 0 zinc-ribbon domain ArfGap PF01412.13 EEQ30835.1 - 0.52 10.1 10.5 2 8.1 0.5 3.1 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.7 EEQ30835.1 - 1 9.1 6.8 2.1 8.1 0.4 2.6 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) COPI_assoc PF08507.5 EEQ30836.1 - 1.3e-43 148.0 4.6 1.3e-43 147.9 3.2 1.0 1 0 0 1 1 1 1 COPI associated protein SPC12 PF06645.8 EEQ30836.1 - 0.64 9.8 3.5 0.25 11.1 0.6 1.7 1 1 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) ExoD PF06055.7 EEQ30836.1 - 2.7 7.0 7.0 0.22 10.5 1.1 1.7 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD DAO PF01266.19 EEQ30837.1 - 1.4e-24 86.6 0.1 3.9e-24 85.2 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ30837.1 - 0.0013 18.6 0.1 0.0032 17.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEQ30837.1 - 0.002 18.4 0.1 0.0058 16.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EEQ30837.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF1188 PF06690.6 EEQ30837.1 - 0.049 12.7 0.0 0.79 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Saccharop_dh PF03435.13 EEQ30837.1 - 0.053 12.4 0.1 0.083 11.8 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 EEQ30837.1 - 0.069 12.5 0.1 0.99 8.8 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EEQ30837.1 - 0.18 10.8 0.1 0.18 10.8 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 EEQ30837.1 - 0.19 11.8 0.3 0.42 10.7 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.17 EEQ30838.1 - 2.2e-31 108.9 0.0 2e-30 105.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Amidinotransf PF02274.12 EEQ30839.1 - 2.9e-11 42.9 0.0 0.00019 20.5 0.0 2.6 2 1 0 2 2 2 2 Amidinotransferase PSDC PF12588.3 EEQ30840.1 - 2.2e-30 105.0 0.0 1.4e-14 53.8 0.0 2.2 1 1 1 2 2 2 2 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EEQ30840.1 - 2.3e-21 76.0 0.0 3.4e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase TauD PF02668.11 EEQ30841.1 - 3.3e-16 59.7 0.2 1.6e-15 57.5 0.1 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EEQ30841.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 CsiD CP_ATPgrasp_2 PF14403.1 EEQ30842.1 - 1.6e-05 23.7 0.0 0.004 15.8 0.0 2.2 2 0 0 2 2 2 2 Circularly permuted ATP-grasp type 2 Glyco_transf_54 PF04666.8 EEQ30844.1 - 7.2e-08 31.5 0.0 6.8e-05 21.7 0.0 3.0 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.12 EEQ30844.1 - 0.0057 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) CUE PF02845.11 EEQ30845.1 - 2.3e-06 26.9 0.1 4.8e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 CUE domain ComX PF05952.7 EEQ30845.1 - 0.11 11.9 0.1 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Thioredoxin PF00085.15 EEQ30846.1 - 6.5e-30 102.8 0.1 7e-30 102.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EEQ30846.1 - 2.7e-09 37.1 0.2 1.5e-08 34.8 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEQ30846.1 - 4.2e-08 33.1 0.0 3.4e-06 27.0 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EEQ30846.1 - 7.3e-05 22.3 0.0 7.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EEQ30846.1 - 0.0001 22.2 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EEQ30846.1 - 0.0004 19.9 0.1 0.0031 17.0 0.1 1.9 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EEQ30846.1 - 0.00048 19.8 0.2 0.0011 18.6 0.1 1.4 1 1 1 2 2 2 1 AhpC/TSA family HyaE PF07449.6 EEQ30846.1 - 0.0028 17.5 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EEQ30846.1 - 0.009 15.8 0.1 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 EEQ30846.1 - 0.033 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_5 PF13743.1 EEQ30846.1 - 0.041 13.4 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.1 EEQ30846.1 - 0.073 13.0 0.0 0.091 12.7 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.19 EEQ30846.1 - 0.088 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF1681 PF07933.9 EEQ30848.1 - 4e-52 175.9 0.0 5.1e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF605 PF04652.11 EEQ30848.1 - 0.22 10.9 3.7 0.24 10.7 2.6 1.2 1 0 0 1 1 1 0 Vta1 like IF-2B PF01008.12 EEQ30849.1 - 1.1e-49 168.9 0.0 1.7e-49 168.3 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family TPR_5 PF12688.2 EEQ30849.1 - 0.064 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat Nuf2 PF03800.9 EEQ30850.1 - 1.8e-43 148.0 1.8 2.3e-43 147.6 0.1 2.0 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 EEQ30850.1 - 0.051 12.7 9.5 1.6 7.8 2.4 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein WPP PF13943.1 EEQ30851.1 - 0.04 14.1 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 WPP domain Adaptin_N PF01602.15 EEQ30852.1 - 1.8e-96 323.5 0.0 2.3e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EEQ30852.1 - 4.3e-11 42.9 2.4 0.00031 20.9 0.0 4.9 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EEQ30852.1 - 1.4e-07 31.0 1.1 0.16 12.0 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EEQ30852.1 - 0.00037 20.8 8.4 0.58 10.7 0.0 5.9 5 2 1 6 6 6 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EEQ30852.1 - 0.018 14.9 0.1 2 8.4 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion VHS PF00790.14 EEQ30852.1 - 0.068 12.8 0.8 42 3.7 0.0 3.9 5 0 0 5 5 5 0 VHS domain Arm PF00514.18 EEQ30852.1 - 0.081 12.7 5.3 1.3 8.9 0.1 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Paf1 PF03985.8 EEQ30852.1 - 3.1 6.4 22.7 6.5 5.3 0.0 2.1 2 0 0 2 2 2 0 Paf1 zf-CCHC_4 PF14392.1 EEQ30853.1 - 0.014 15.0 1.0 0.032 13.8 0.5 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EEQ30853.1 - 0.022 14.6 1.8 0.035 14.0 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF445 PF04286.7 EEQ30853.1 - 0.024 14.1 1.4 0.031 13.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SseC PF04888.7 EEQ30853.1 - 0.11 11.8 0.4 0.16 11.3 0.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Prominin PF05478.6 EEQ30853.1 - 0.41 8.1 0.3 0.53 7.7 0.2 1.0 1 0 0 1 1 1 0 Prominin CT47 PF15623.1 EEQ30853.1 - 0.41 10.3 28.1 0.68 9.6 19.5 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Mor PF08765.6 EEQ30853.1 - 0.84 9.4 2.7 2 8.2 1.2 1.9 1 1 1 2 2 2 0 Mor transcription activator family HK97-gp10_like PF04883.7 EEQ30853.1 - 1.9 9.5 4.4 3 8.8 1.4 2.2 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component IFT57 PF10498.4 EEQ30853.1 - 2.4 6.7 10.1 3.7 6.1 7.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CBFD_NFYB_HMF PF00808.18 EEQ30853.1 - 3.7 7.6 13.0 7.3 6.7 6.4 2.4 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Metallophos PF00149.23 EEQ30854.1 - 2.8e-42 144.3 0.5 3.7e-42 143.9 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 EEQ30855.1 - 6.2e-61 205.3 0.1 6.8e-61 205.1 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor GFA PF04828.9 EEQ30856.1 - 5e-08 32.7 1.4 5e-08 32.7 0.9 1.9 1 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.8 EEQ30856.1 - 0.0005 19.5 3.1 0.00061 19.2 0.6 2.0 2 0 0 2 2 2 1 CSL zinc finger zf-NADH-PPase PF09297.6 EEQ30856.1 - 0.0036 16.7 0.5 0.0036 16.7 0.4 2.3 2 1 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 EEQ30856.1 - 0.015 14.9 0.1 0.015 14.9 0.0 2.4 2 1 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.1 EEQ30856.1 - 0.029 13.5 0.5 0.029 13.5 0.4 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Cys_rich_CWC PF14375.1 EEQ30856.1 - 0.038 13.9 0.5 0.038 13.9 0.3 1.8 2 0 0 2 2 2 0 Cysteine-rich CWC AAA_24 PF13479.1 EEQ30856.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4610 PF15384.1 EEQ30857.1 - 0.025 14.1 0.8 0.025 14.1 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4610) KilA-N PF04383.8 EEQ30857.1 - 0.039 13.5 0.1 1.5 8.4 0.0 2.8 2 1 0 2 2 2 0 KilA-N domain Clp1 PF06807.9 EEQ30858.1 - 2e-17 63.6 0.0 7e-10 38.9 0.0 2.7 2 1 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EEQ30858.1 - 2.4e-08 33.7 0.0 4.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EEQ30858.1 - 8.1e-05 22.2 0.0 0.0026 17.3 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EEQ30858.1 - 0.00054 19.9 0.0 0.0026 17.6 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEQ30858.1 - 0.058 12.6 0.1 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EEQ30858.1 - 0.058 12.8 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EEQ30858.1 - 0.089 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EEQ30858.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_35 PF14516.1 EEQ30858.1 - 0.23 10.0 0.0 0.35 9.4 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Sgf11 PF08209.6 EEQ30859.1 - 0.056 12.7 0.1 0.056 12.7 0.1 2.7 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) ADH_zinc_N PF00107.21 EEQ30860.1 - 8.6e-31 106.1 0.0 1.4e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ30860.1 - 4.1e-20 72.9 0.0 8.1e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ30860.1 - 2.4e-09 36.9 0.0 7.9e-09 35.2 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NCU-G1 PF15065.1 EEQ30861.1 - 0.038 12.6 1.1 1.9 7.0 0.1 2.1 1 1 1 2 2 2 0 Lysosomal transcription factor, NCU-G1 Fringe PF02434.11 EEQ30862.1 - 2.3e-06 26.9 0.5 7.3e-05 22.1 0.1 2.5 2 1 0 2 2 2 1 Fringe-like PAN_1 PF00024.21 EEQ30862.1 - 0.00054 19.6 1.0 0.00094 18.8 0.7 1.3 1 0 0 1 1 1 1 PAN domain Glyco_tranf_2_3 PF13641.1 EEQ30862.1 - 0.014 15.2 0.0 0.83 9.4 0.0 2.3 1 1 1 2 2 2 0 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EEQ30862.1 - 0.028 14.1 0.4 0.29 10.8 0.3 2.1 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Galactosyl_T PF01762.16 EEQ30862.1 - 0.074 12.6 0.0 1.5 8.4 0.0 2.2 1 1 1 2 2 2 0 Galactosyltransferase PAN_4 PF14295.1 EEQ30862.1 - 0.2 11.4 1.7 0.38 10.4 1.2 1.4 1 0 0 1 1 1 0 PAN domain Arb1 PF09692.5 EEQ30863.1 - 6.1e-131 436.9 5.0 4.5e-129 430.7 3.4 2.1 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 EEQ30864.1 - 2.6e-60 203.4 0.0 3.2e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_S19 PF00203.16 EEQ30865.1 - 6e-21 73.8 0.0 6.7e-21 73.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 EEQ30866.1 - 2.4e-23 81.6 0.1 4e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 EEQ30866.1 - 0.12 12.7 2.7 0.35 11.3 1.9 1.8 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 CDC27 PF09507.5 EEQ30866.1 - 4.7 6.3 13.4 6.5 5.8 9.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TRF PF08558.5 EEQ30868.1 - 1.2e-79 267.0 0.1 2.2e-79 266.1 0.1 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EEQ30868.1 - 1.6e-05 24.8 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ30868.1 - 0.081 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4578 PF15147.1 EEQ30868.1 - 0.68 10.3 5.2 0.45 10.8 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) His_Phos_2 PF00328.17 EEQ30869.1 - 1.6e-09 37.6 0.0 1.2e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) DUF3804 PF12707.2 EEQ30870.1 - 0.077 12.5 0.1 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3804) MFS_1 PF07690.11 EEQ30871.1 - 1.8e-30 105.8 45.4 7.9e-27 93.8 33.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EEQ30871.1 - 0.014 15.3 0.3 0.014 15.3 0.2 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF4006 PF13179.1 EEQ30871.1 - 0.16 11.5 3.8 0.16 11.5 0.3 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF4267 PF14087.1 EEQ30872.1 - 2.6e-27 94.6 5.9 3.1e-27 94.3 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF998 PF06197.8 EEQ30872.1 - 0.26 10.5 11.5 0.77 9.0 8.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF2892 PF11127.3 EEQ30872.1 - 1.5 8.6 11.0 0.16 11.7 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) DUF308 PF03729.8 EEQ30872.1 - 4.4 7.3 11.1 30 4.6 5.1 2.6 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) Pkinase PF00069.20 EEQ30873.1 - 4.6e-71 239.0 0.0 8.7e-71 238.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30873.1 - 3.2e-31 108.3 0.0 1.4e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ30873.1 - 1e-05 24.6 0.0 0.36 9.7 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EEQ30873.1 - 0.035 13.1 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DASH_Dad3 PF08656.5 EEQ30874.1 - 1.1e-26 92.2 0.9 1.7e-26 91.6 0.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad3 RINT1_TIP1 PF04437.8 EEQ30874.1 - 0.025 13.1 0.3 0.024 13.2 0.2 1.1 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Ribosomal_S5_C PF03719.10 EEQ30875.1 - 3.7e-18 64.5 0.0 9.1e-18 63.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EEQ30875.1 - 5.1e-11 42.1 0.1 1.1e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Nbs1_C PF08599.5 EEQ30875.1 - 0.2 11.6 1.5 0.29 11.0 0.2 1.9 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 APH PF01636.18 EEQ30877.1 - 5.3e-10 39.4 0.0 1.6e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ30877.1 - 8.7e-05 22.1 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ30877.1 - 0.00029 20.0 0.0 0.0014 17.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain CRAL_TRIO PF00650.15 EEQ30877.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO domain Fructosamin_kin PF03881.9 EEQ30877.1 - 0.2 10.5 0.1 1.5 7.7 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase COX2-transmemb PF09125.5 EEQ30878.1 - 0.075 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane APH PF01636.18 EEQ30879.1 - 3.2e-14 53.2 0.1 5.9e-13 49.1 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.2 EEQ30880.1 - 3.9e-99 325.1 5.8 4.5e-18 65.3 0.0 11.2 3 3 9 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ30880.1 - 4.3e-80 259.8 25.5 4.1e-08 32.6 0.1 19.5 21 0 0 21 21 21 16 Ankyrin repeat Ank_4 PF13637.1 EEQ30880.1 - 1.2e-74 245.4 25.3 4.4e-08 33.4 0.1 16.0 8 3 8 17 17 17 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ30880.1 - 5.6e-56 185.2 21.1 5.1e-08 32.9 0.1 16.2 11 5 7 19 19 19 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ30880.1 - 1.5e-52 170.3 25.4 0.00016 21.5 0.0 19.2 20 0 0 20 20 20 11 Ankyrin repeat DUF3447 PF11929.3 EEQ30880.1 - 0.00033 20.3 0.0 0.074 12.8 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) DUF4158 PF13700.1 EEQ30880.1 - 0.11 12.0 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) tRNA_U5-meth_tr PF05958.6 EEQ30881.1 - 4.5e-17 61.7 0.1 1e-14 54.0 0.0 3.3 2 2 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EEQ30881.1 - 2.8e-07 30.2 0.0 7.1e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EEQ30881.1 - 0.00021 20.9 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EEQ30881.1 - 0.00042 20.8 0.0 0.00084 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EEQ30881.1 - 0.0011 18.7 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 TRAM domain Methyltransf_11 PF08241.7 EEQ30881.1 - 0.0033 17.8 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ30881.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EEQ30881.1 - 0.022 13.9 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEQ30881.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Actin PF00022.14 EEQ30882.1 - 5.9e-90 301.5 0.0 9.6e-90 300.8 0.0 1.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEQ30882.1 - 0.00012 20.8 0.1 0.0038 15.8 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Asparaginase_2 PF01112.13 EEQ30883.1 - 4.5e-38 130.7 2.9 4.5e-22 78.1 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 EEQ30884.1 - 2.7e-112 374.5 0.0 3.5e-112 374.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.8 EEQ30884.1 - 0.29 10.9 5.2 0.55 10.0 3.6 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF1180 PF06679.7 EEQ30884.1 - 1.6 8.5 9.6 0.52 10.1 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) UNC45-central PF11701.3 EEQ30885.1 - 8.4e-37 126.2 0.0 2.2e-34 118.4 0.0 3.4 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Arm PF00514.18 EEQ30885.1 - 0.00098 18.8 3.5 16 5.5 0.0 5.4 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Stig1 PF04885.8 EEQ30886.1 - 1.4e-05 25.2 73.7 0.017 15.2 19.9 3.5 1 1 2 3 3 3 3 Stigma-specific protein, Stig1 TM231 PF10149.4 EEQ30886.1 - 0.11 11.5 0.0 0.21 10.5 0.0 1.4 1 1 0 1 1 1 0 Transmembrane protein 231 APH PF01636.18 EEQ30887.1 - 1.6e-09 37.8 0.2 2e-08 34.2 0.1 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family GDPD PF03009.12 EEQ30888.1 - 3.8e-55 187.1 0.0 7e-55 186.2 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EEQ30888.1 - 9.2e-31 106.0 2.5 8.6e-13 48.4 0.7 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.14 EEQ30888.1 - 7.3e-30 104.6 8.1 9.8e-18 64.9 1.4 3.6 2 1 1 3 3 3 2 SPX domain Ank_4 PF13637.1 EEQ30888.1 - 6.1e-27 93.4 2.7 8.7e-09 35.6 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EEQ30888.1 - 1.6e-25 87.6 3.5 5.1e-07 29.1 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EEQ30888.1 - 1.8e-20 72.4 1.3 0.0001 22.3 0.0 4.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ30888.1 - 2e-15 55.3 2.2 0.003 17.6 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat TAT_signal PF10518.4 EEQ30888.1 - 0.11 12.5 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PRMT5 PF05185.11 EEQ30889.1 - 4.9e-166 553.1 0.0 6e-166 552.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CX PF01705.14 EEQ30889.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 CX module Hamartin PF04388.7 EEQ30889.1 - 8.8 4.8 8.1 25 3.3 5.3 1.7 1 1 1 2 2 2 0 Hamartin protein OB_NTP_bind PF07717.11 EEQ30890.1 - 7.7e-25 86.9 0.0 1.7e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEQ30890.1 - 4.9e-24 84.2 0.1 2.1e-23 82.2 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ30890.1 - 3.2e-10 39.7 0.0 7.7e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ30890.1 - 1.2e-06 28.0 0.2 2.4e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEQ30890.1 - 1.8e-05 24.8 0.1 9.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EEQ30890.1 - 0.00053 19.4 0.1 0.0014 18.1 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EEQ30890.1 - 0.0017 18.2 0.0 0.72 9.6 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EEQ30890.1 - 0.0027 17.4 0.1 0.0052 16.5 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EEQ30890.1 - 0.017 14.0 0.0 0.037 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EEQ30890.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain EF-hand_6 PF13405.1 EEQ30892.1 - 2.9e-09 36.0 0.2 0.0002 20.9 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EEQ30892.1 - 0.00077 19.5 1.5 0.0015 18.6 0.1 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EEQ30892.1 - 0.018 14.2 0.0 0.51 9.7 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 EEQ30892.1 - 0.13 11.9 0.0 1 9.0 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain pair Met_10 PF02475.11 EEQ30893.1 - 0.00012 21.7 0.0 0.00028 20.5 0.0 1.7 1 1 0 1 1 1 1 Met-10+ like-protein DUF1083 PF06452.6 EEQ30894.1 - 6.1e-05 22.9 0.0 7.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1083) CBM_20 PF00686.14 EEQ30895.1 - 0.15 11.6 0.4 0.25 10.9 0.3 1.3 1 0 0 1 1 1 0 Starch binding domain MFS_1 PF07690.11 EEQ30896.1 - 4.1e-26 91.5 67.5 3.9e-23 81.7 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_1 PF00515.23 EEQ30897.1 - 0.12 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.27 EEQ30898.1 - 1.5e-08 34.2 0.3 7.7e-05 22.4 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EEQ30898.1 - 0.00035 19.5 0.0 0.014 14.2 0.0 2.2 2 0 0 2 2 2 1 Coatomer WD associated region CPSF_A PF03178.10 EEQ30898.1 - 0.011 14.7 0.1 0.42 9.6 0.0 2.5 2 1 0 2 2 2 0 CPSF A subunit region Hira PF07569.6 EEQ30898.1 - 0.014 14.6 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split CNH PF00780.17 EEQ30898.1 - 0.027 13.8 0.1 1.8 7.8 0.1 2.8 2 1 0 2 2 2 0 CNH domain Apc4_WD40 PF12894.2 EEQ30898.1 - 0.061 12.8 0.0 2.4 7.7 0.0 2.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Kelch_4 PF13418.1 EEQ30899.1 - 4.8e-19 67.8 14.8 1.9e-08 33.9 0.1 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain LCM PF04072.9 EEQ30899.1 - 7.5e-19 67.9 0.0 1.2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_3 PF13415.1 EEQ30899.1 - 1.7e-10 40.7 14.7 0.00028 20.9 0.1 6.1 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EEQ30899.1 - 6.1e-05 22.8 2.2 0.057 13.4 0.0 4.3 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 EEQ30899.1 - 0.0025 17.3 0.5 3.1 7.3 0.0 4.9 6 1 0 6 6 6 1 Kelch motif Kelch_2 PF07646.10 EEQ30899.1 - 0.0042 16.7 3.9 17 5.4 0.0 4.9 5 0 0 5 5 5 1 Kelch motif FmrO PF07091.6 EEQ30899.1 - 0.03 13.3 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ADH_zinc_N PF00107.21 EEQ30900.1 - 4.1e-11 42.5 0.0 9.9e-11 41.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.5 EEQ30900.1 - 0.0097 15.5 0.2 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EEQ30900.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 EEQ30900.1 - 0.041 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_N PF08240.7 EEQ30900.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DSPc PF00782.15 EEQ30901.1 - 8.5e-27 93.3 0.0 3e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEQ30901.1 - 0.00023 20.5 0.0 0.00091 18.6 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DNA_mis_repair PF01119.14 EEQ30903.1 - 7.5e-32 109.2 0.0 2.2e-31 107.7 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EEQ30903.1 - 0.00024 20.7 0.4 0.045 13.4 0.0 2.7 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase APH PF01636.18 EEQ30904.1 - 1.5e-06 28.1 0.1 0.00022 21.0 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ30904.1 - 0.0018 17.9 0.1 0.0026 17.3 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ30904.1 - 0.031 13.6 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Exosortase_EpsH PF09721.5 EEQ30905.1 - 0.028 13.6 0.1 0.033 13.4 0.1 1.0 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) PC_rep PF01851.17 EEQ30908.1 - 1.1e-20 72.6 12.7 7.5e-05 22.7 0.1 8.8 9 0 0 9 9 9 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EEQ30908.1 - 0.00036 20.7 0.9 1.1 9.6 0.0 3.8 4 0 0 4 4 4 2 HEAT repeats TPR_5 PF12688.2 EEQ30908.1 - 0.035 14.1 0.6 4.3 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratrico peptide repeat DUF1987 PF09345.5 EEQ30908.1 - 0.06 13.1 0.2 6.3 6.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1987) BTK PF00779.14 EEQ30909.1 - 0.033 13.8 2.0 0.082 12.5 1.4 1.7 1 0 0 1 1 1 0 BTK motif Cyclin PF08613.6 EEQ30911.1 - 6.4e-16 59.0 0.0 1.2e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEQ30911.1 - 0.0021 17.6 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TMEM141 PF15110.1 EEQ30912.1 - 0.057 13.7 0.1 0.09 13.0 0.1 1.3 1 0 0 1 1 1 0 TMEM141 protein family Pyr_redox_2 PF07992.9 EEQ30913.1 - 6.2e-19 68.6 0.0 8.7e-18 64.9 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ30913.1 - 1.2e-12 48.0 0.0 3.9e-11 43.1 0.0 2.7 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ30913.1 - 0.0033 17.5 0.8 1.8 8.5 0.1 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HemY_N PF07219.8 EEQ30914.1 - 0.12 11.9 0.5 0.21 11.1 0.3 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Acetyltransf_7 PF13508.1 EEQ30915.1 - 5.6e-09 36.0 0.1 9.6e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ30915.1 - 1.9e-08 34.2 0.0 2.8e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EEQ30915.1 - 1.1e-06 28.4 0.0 0.0012 18.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ30915.1 - 1.9e-06 28.0 0.0 1.5e-05 25.1 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ30915.1 - 3.4e-05 23.4 0.0 9.6e-05 22.0 0.0 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 EEQ30915.1 - 0.00023 20.9 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Arrestin_C PF02752.17 EEQ30916.1 - 8.5e-17 61.5 0.0 4.6e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEQ30916.1 - 6.6e-10 38.9 0.0 6.2e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DUF1076 PF06416.7 EEQ30916.1 - 0.095 12.4 0.2 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1076) Vps23_core PF09454.5 EEQ30917.1 - 0.14 11.7 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Vps23 core domain RRM_1 PF00076.17 EEQ30918.1 - 1.9e-59 197.1 0.0 4.2e-21 74.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ30918.1 - 3.4e-44 148.6 0.0 3.6e-14 52.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ30918.1 - 4.4e-30 103.3 0.0 8.7e-10 38.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ30918.1 - 1.1e-06 28.3 0.0 0.096 12.4 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EEQ30918.1 - 0.0022 17.6 0.0 9.5 6.0 0.0 3.3 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EEQ30918.1 - 0.0062 16.4 0.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) DUF2956 PF11169.3 EEQ30919.1 - 0.43 10.5 4.4 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) PIG-Y PF15159.1 EEQ30919.1 - 7 6.9 9.1 36 4.6 6.3 2.2 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y GATase_4 PF13230.1 EEQ30920.1 - 8.8e-15 54.1 0.0 1.2e-13 50.4 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEQ30920.1 - 1e-08 35.2 0.0 2.8e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EEQ30920.1 - 3.1e-06 26.1 0.2 0.00021 20.1 0.3 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Kazal_2 PF07648.10 EEQ30921.1 - 1.6e-07 31.1 0.9 2.3e-07 30.6 0.6 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EEQ30921.1 - 1e-05 25.4 1.1 1.4e-05 25.0 0.8 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Dynamin_N PF00350.18 EEQ30922.1 - 1.5e-43 148.4 0.0 3.5e-43 147.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ30922.1 - 1.2e-10 40.6 0.4 3.4e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EEQ30922.1 - 0.00087 19.2 0.0 0.0025 17.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ30922.1 - 0.005 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EEQ30922.1 - 0.036 14.0 0.9 0.43 10.5 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Ribosomal_S6 PF01250.12 EEQ30923.1 - 1.5e-08 34.3 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.14 EEQ30924.1 - 6.7e-42 142.0 2.2 8e-42 141.7 1.6 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EEQ30924.1 - 0.0026 17.4 0.2 0.0036 16.9 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EEQ30924.1 - 0.0046 16.5 0.7 0.008 15.7 0.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme zf-rbx1 PF12678.2 EEQ30925.1 - 4.6e-10 39.4 0.7 8.2e-10 38.6 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEQ30925.1 - 1.6e-08 34.2 10.8 3e-07 30.1 7.5 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ30925.1 - 3.4e-07 29.8 2.8 9.9e-07 28.3 2.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ30925.1 - 1.5e-06 27.7 4.8 7.2e-06 25.5 3.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ30925.1 - 1.9e-06 27.3 1.0 3.3e-06 26.6 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ30925.1 - 1.2e-05 25.1 3.1 1.2e-05 25.1 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ30925.1 - 0.0034 17.1 1.2 0.0086 15.8 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 EEQ30925.1 - 0.047 11.4 0.7 0.07 10.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-RING_UBOX PF13445.1 EEQ30925.1 - 0.097 12.4 3.1 0.15 11.8 0.8 2.4 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EEQ30925.1 - 3.7 7.5 6.1 4.2 7.4 2.4 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 EEQ30925.1 - 4.3 7.4 6.4 0.73 9.9 1.5 1.9 2 0 0 2 2 2 0 RING-variant domain Cation_efflux PF01545.16 EEQ30926.1 - 1.4e-35 122.7 8.2 1.8e-35 122.4 5.7 1.1 1 0 0 1 1 1 1 Cation efflux family COMPASS-Shg1 PF05205.7 EEQ30929.1 - 5e-29 100.7 0.1 5e-29 100.7 0.0 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.13 EEQ30930.1 - 1.8e-33 115.4 0.3 2.1e-33 115.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.1 EEQ30931.1 - 1.9e-25 89.3 1.3 1.9e-25 89.3 0.9 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) AF-4 PF05110.8 EEQ30931.1 - 0.018 12.9 17.7 0.02 12.7 12.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF605 PF04652.11 EEQ30931.1 - 0.65 9.3 12.3 0.84 8.9 8.5 1.2 1 0 0 1 1 1 0 Vta1 like CENP-B_dimeris PF09026.5 EEQ30931.1 - 5.1 7.3 9.3 0.12 12.6 0.5 2.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain GDA1_CD39 PF01150.12 EEQ30932.1 - 1.7e-98 329.9 0.0 2.2e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family IF3_C PF00707.17 EEQ30933.1 - 1e-13 50.8 0.8 1.6e-13 50.2 0.6 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 EEQ30933.1 - 5e-07 29.5 0.7 8.2e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.1 EEQ30933.1 - 1.7e-06 27.4 0.2 2.7e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor GTP_EFTU PF00009.22 EEQ30934.1 - 9.5e-61 204.5 0.0 1.3e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEQ30934.1 - 3.2e-22 78.5 0.0 7.8e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEQ30934.1 - 9.5e-18 64.0 1.6 2.5e-17 62.7 1.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ30934.1 - 3.8e-05 23.5 0.0 7.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EEQ30934.1 - 0.00072 19.1 0.2 0.0019 17.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EEQ30934.1 - 0.0011 19.4 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EEQ30934.1 - 0.031 13.7 0.2 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Hepatitis_core PF00906.15 EEQ30934.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Hepatitis core antigen cobW PF02492.14 EEQ30934.1 - 0.11 11.9 0.3 0.55 9.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Radical_SAM PF04055.16 EEQ30935.1 - 3.2e-14 53.4 0.0 1.5e-13 51.2 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EEQ30935.1 - 1.4e-08 34.7 0.0 3.2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EEQ30935.1 - 1.5e-08 34.8 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain ABM PF03992.11 EEQ30938.1 - 3.9e-05 23.6 1.0 0.062 13.3 0.0 3.0 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.11 EEQ30939.1 - 1.4e-40 139.1 55.1 1.4e-40 139.1 38.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ30939.1 - 5.2e-15 54.6 27.0 7.3e-15 54.1 18.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 EEQ30940.1 - 4.9e-05 23.1 8.8 0.00014 21.7 6.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LpxB PF02684.10 EEQ30940.1 - 0.019 13.6 2.6 0.059 11.9 1.3 1.9 2 0 0 2 2 2 0 Lipid-A-disaccharide synthetase Cytochrome_C7 PF14522.1 EEQ30940.1 - 0.25 11.0 9.9 5.7 6.6 0.1 2.7 2 0 0 2 2 2 0 Cytochrome c7 Paired_CXXCH_1 PF09699.5 EEQ30940.1 - 1.1 8.8 8.6 2.9 7.4 0.3 3.3 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) PAT1 PF09770.4 EEQ30940.1 - 3 5.9 25.3 4.5 5.3 17.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DivIC PF04977.10 EEQ30940.1 - 4.7 6.7 11.6 30 4.1 6.8 2.4 2 0 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.11 EEQ30942.1 - 1.6e-23 83.0 41.6 1.6e-23 83.0 28.8 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ30942.1 - 4.4e-09 35.4 8.1 4.4e-09 35.4 5.6 3.5 4 1 1 5 5 5 2 Sugar (and other) transporter DUF879 PF05947.7 EEQ30942.1 - 0.032 12.5 0.0 0.045 12.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) NAGLU PF05089.7 EEQ30942.1 - 0.046 12.4 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain RHD3 PF05879.7 EEQ30943.1 - 0 1046.2 0.0 0 1046.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EEQ30943.1 - 1.3e-08 34.1 0.2 2.4e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EEQ30943.1 - 2.7e-06 27.2 0.1 5.5e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EEQ30943.1 - 0.0001 22.1 0.1 0.00023 21.0 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EEQ30943.1 - 0.00012 22.0 0.1 0.00073 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Septin PF00735.13 EEQ30943.1 - 0.00059 18.9 0.1 0.0012 17.8 0.1 1.5 1 0 0 1 1 1 1 Septin Miro PF08477.8 EEQ30943.1 - 0.00094 19.6 0.1 0.0021 18.5 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein Transp_cyt_pur PF02133.10 EEQ30944.1 - 5.8e-83 278.8 28.9 6.8e-82 275.3 20.0 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin McyA_C PF12593.3 EEQ30944.1 - 0.038 13.7 0.1 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Microcystin synthetase C terminal APH PF01636.18 EEQ30945.1 - 8.7e-06 25.6 0.0 4.5e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DIM1 PF02966.11 EEQ30946.1 - 3.1e-70 233.8 0.3 3.5e-70 233.7 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EEQ30946.1 - 0.014 15.5 0.4 0.024 14.7 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.15 EEQ30946.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin 4HBT_2 PF13279.1 EEQ30947.1 - 1.8e-10 41.3 0.0 2.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.8 EEQ30948.1 - 1.2e-07 31.3 0.2 1.2e-07 31.3 0.2 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF3425 PF11905.3 EEQ30949.1 - 6.6e-35 119.9 0.3 1.3e-34 118.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EEQ30949.1 - 0.0038 17.1 4.9 0.0072 16.2 3.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ30949.1 - 0.058 13.2 5.7 0.1 12.4 4.0 1.3 1 0 0 1 1 1 0 Basic region leucine zipper adh_short PF00106.20 EEQ30950.1 - 3.4e-08 33.5 0.0 5.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ30950.1 - 4.4e-06 26.4 0.0 7.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Med26 PF08711.6 EEQ30951.1 - 2.1e-11 43.1 0.0 3.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nup54 PF13874.1 EEQ30952.1 - 4.8e-46 155.9 0.6 4.8e-46 155.9 0.4 2.5 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EEQ30952.1 - 3.4e-07 30.4 70.5 5.4e-06 26.6 13.5 3.2 1 1 1 2 2 2 2 Nucleoporin FG repeat region Uds1 PF15456.1 EEQ30952.1 - 7.2 6.6 10.3 25 4.8 1.4 2.8 1 1 1 2 2 2 0 Up-regulated During Septation AAA PF00004.24 EEQ30953.1 - 4e-15 56.1 0.0 2.5e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ30953.1 - 5.3e-11 42.8 0.2 1.7e-09 37.9 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ30953.1 - 1.6e-08 34.7 0.0 1.6e-07 31.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ30953.1 - 9.7e-06 25.2 0.1 4.4e-05 23.1 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EEQ30953.1 - 0.00042 21.1 0.0 0.0063 17.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain Pol_alpha_B_N PF08418.5 EEQ30953.1 - 0.00056 19.5 4.3 0.079 12.4 0.4 2.3 2 0 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal AAA_11 PF13086.1 EEQ30953.1 - 0.00099 18.7 0.0 0.0021 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEQ30953.1 - 0.001 19.0 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEQ30953.1 - 0.0026 17.4 0.0 0.0098 15.5 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EEQ30953.1 - 0.0072 16.0 0.0 0.065 12.9 0.0 2.4 1 1 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EEQ30953.1 - 0.0075 16.4 0.0 0.081 13.1 0.0 2.8 4 0 0 4 4 3 1 RNA helicase KAP_NTPase PF07693.9 EEQ30953.1 - 0.0093 14.9 0.0 0.051 12.5 0.0 2.0 2 0 0 2 2 2 1 KAP family P-loop domain AAA_33 PF13671.1 EEQ30953.1 - 0.0094 15.8 0.0 0.24 11.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.4 EEQ30953.1 - 0.035 13.0 0.0 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) BAH PF01426.13 EEQ30953.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 BAH domain PIF1 PF05970.9 EEQ30953.1 - 0.048 12.6 0.0 0.099 11.5 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase UvrD-helicase PF00580.16 EEQ30953.1 - 0.063 12.5 0.0 0.59 9.3 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Zot PF05707.7 EEQ30953.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_32 PF13654.1 EEQ30953.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EEQ30953.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 NTPase WD40 PF00400.27 EEQ30954.1 - 1.1e-49 164.5 12.2 2.6e-10 39.7 0.1 6.4 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EEQ30954.1 - 0.0037 15.4 3.2 5.2 5.0 0.1 3.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Ank_2 PF12796.2 EEQ30955.1 - 2.4e-37 127.1 2.2 6.4e-17 61.6 0.3 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ30955.1 - 1.5e-30 104.4 4.5 9.4e-10 38.4 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ30955.1 - 3e-30 104.0 9.8 1.1e-07 32.1 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EEQ30955.1 - 2e-28 96.7 1.5 1.6e-05 24.4 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EEQ30955.1 - 7.6e-26 87.6 1.4 0.0012 18.8 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.3 EEQ30955.1 - 0.019 14.4 0.3 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels DUF484 PF04340.7 EEQ30955.1 - 0.069 12.6 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF484 TMF_TATA_bd PF12325.3 EEQ30956.1 - 2.8e-42 143.2 10.2 2.8e-42 143.2 7.1 6.8 3 2 3 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EEQ30956.1 - 1.4e-20 72.8 12.5 1.4e-20 72.8 8.7 9.2 6 4 3 10 10 10 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EEQ30956.1 - 0.00018 21.3 1.4 0.00018 21.3 1.0 6.7 2 1 5 7 7 7 1 Autophagy protein 16 (ATG16) UBA_e1_C PF09358.5 EEQ30956.1 - 0.39 10.8 2.4 1.2 9.3 0.0 2.8 2 0 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain NPV_P10 PF05531.7 EEQ30956.1 - 8.2 6.7 18.5 1.9 8.8 0.3 5.8 7 0 0 7 7 7 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.20 EEQ30957.1 - 3.3e-14 52.6 0.0 4.5e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ30957.1 - 3.2e-13 49.3 0.0 1.3e-12 47.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PemK PF02452.12 EEQ30957.1 - 0.043 14.0 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 PemK-like protein DUF479 PF04336.7 EEQ30957.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF479 V-ATPase_H_N PF03224.9 EEQ30958.1 - 2.1e-80 270.1 0.0 2.9e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EEQ30958.1 - 4.5e-40 136.2 0.0 1.2e-39 134.8 0.0 1.8 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.1 EEQ30958.1 - 0.53 10.6 3.6 1 9.6 0.1 3.1 3 1 0 3 3 3 0 HEAT repeats EFP PF01132.15 EEQ30959.1 - 0.034 13.8 0.1 0.085 12.5 0.1 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain Filament PF00038.16 EEQ30959.1 - 8.7 5.7 63.1 0.056 12.9 11.6 5.8 6 0 0 6 6 6 0 Intermediate filament protein MFS_1 PF07690.11 EEQ30960.1 - 6.6e-16 57.9 43.2 2.9e-15 55.8 29.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily CUE PF02845.11 EEQ30960.1 - 0.06 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 CUE domain Apq12 PF12716.2 EEQ30962.1 - 6.7e-22 76.9 13.6 9.3e-22 76.4 9.4 1.2 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.12 EEQ30963.1 - 1.2e-74 250.8 0.0 1.5e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EEQ30963.1 - 3.2e-06 27.9 0.0 1.2e-05 26.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ30963.1 - 0.00014 22.0 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ30963.1 - 0.00015 21.6 0.0 0.00046 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ30963.1 - 0.00089 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 EEQ30963.1 - 0.00096 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EEQ30963.1 - 0.0012 18.8 0.0 0.0044 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EEQ30963.1 - 0.0018 18.4 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEQ30963.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EEQ30963.1 - 0.0035 16.7 0.1 2.4 7.5 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain T2SE PF00437.15 EEQ30963.1 - 0.0037 16.2 0.0 0.007 15.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_31 PF13614.1 EEQ30963.1 - 0.0038 17.1 0.0 0.016 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEQ30963.1 - 0.004 17.2 0.0 0.0089 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase SRP54 PF00448.17 EEQ30963.1 - 0.0058 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 EEQ30963.1 - 0.0069 15.8 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain UPF0079 PF02367.12 EEQ30963.1 - 0.0089 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EEQ30963.1 - 0.0094 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 EEQ30963.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EEQ30963.1 - 0.024 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEQ30963.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 EEQ30963.1 - 0.035 14.4 0.0 0.064 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEQ30963.1 - 0.039 13.4 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain cobW PF02492.14 EEQ30963.1 - 0.04 13.3 0.1 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EEQ30963.1 - 0.043 13.5 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 EEQ30963.1 - 0.052 13.0 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EEQ30963.1 - 0.054 13.1 0.0 0.64 9.6 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase KaiC PF06745.8 EEQ30963.1 - 0.057 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 EEQ30963.1 - 0.058 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEQ30963.1 - 0.062 12.7 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.4 EEQ30963.1 - 0.071 12.5 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EEQ30963.1 - 0.096 11.6 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_10 PF12846.2 EEQ30963.1 - 0.099 12.0 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.21 EEQ30963.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EEQ30963.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.9 EEQ30963.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EEQ30963.1 - 0.13 12.1 0.0 0.49 10.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase KTI12 PF08433.5 EEQ30963.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EEQ30963.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin S-AdoMet_synt_C PF02773.11 EEQ30964.1 - 2.8e-67 224.6 0.3 5.8e-67 223.6 0.1 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.15 EEQ30964.1 - 1.1e-39 134.6 0.6 5.3e-39 132.4 0.4 2.0 1 1 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.11 EEQ30964.1 - 3.5e-14 52.7 0.0 9.2e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain SLD3 PF08639.5 EEQ30965.1 - 9.2e-119 397.2 3.8 1.8e-118 396.3 2.6 1.4 1 0 0 1 1 1 1 DNA replication regulator SLD3 HNH_2 PF13391.1 EEQ30966.1 - 7.4e-17 60.8 0.1 1.6e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease CRC_subunit PF08624.5 EEQ30967.1 - 5.7e-55 185.0 0.2 9e-55 184.3 0.1 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Homeobox PF00046.24 EEQ30968.1 - 4.8e-16 58.1 2.8 1.6e-15 56.4 1.9 1.9 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EEQ30968.1 - 0.00028 20.5 0.5 0.00028 20.5 0.3 2.0 2 0 0 2 2 2 1 Homeobox KN domain MRP-L46 PF11788.3 EEQ30968.1 - 0.67 10.6 11.4 0.39 11.3 6.2 1.9 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Dicty_REP PF05086.7 EEQ30968.1 - 3.1 5.4 6.7 4.2 5.0 4.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HAD_2 PF13419.1 EEQ30969.1 - 4.8e-17 62.7 0.0 6.7e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ30969.1 - 3.4e-10 40.6 0.1 4.6e-08 33.7 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ30969.1 - 5.6e-09 35.5 0.1 1.4e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EEQ30969.1 - 0.0024 18.0 0.1 0.0057 16.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EEQ30969.1 - 0.0025 17.6 0.2 0.044 13.6 0.1 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.6 EEQ30970.1 - 6e-25 86.9 15.0 1.5e-24 85.6 10.4 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EEQ30970.1 - 3.2e-22 78.6 0.3 1.6e-15 57.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ30970.1 - 6.4e-06 25.5 0.2 4.2e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEQ30970.1 - 7.9e-06 25.7 3.6 0.44 10.3 0.0 3.7 3 1 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.22 EEQ30970.1 - 6.5e-05 22.4 0.0 0.12 11.7 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEQ30970.1 - 0.0001 21.4 0.2 0.00018 20.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EEQ30970.1 - 0.0013 19.1 0.2 1.3 9.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AIG1 PF04548.11 EEQ30970.1 - 0.0054 15.8 0.2 0.02 14.0 0.1 1.9 2 0 0 2 2 2 1 AIG1 family cobW PF02492.14 EEQ30970.1 - 0.007 15.8 1.7 0.96 8.8 0.0 3.5 3 1 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EEQ30970.1 - 0.013 15.8 0.8 0.04 14.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 EEQ30970.1 - 0.014 14.1 0.1 0.039 12.7 0.1 1.7 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 EEQ30970.1 - 0.088 12.5 0.1 0.26 11.0 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EEQ30970.1 - 0.19 11.7 2.8 0.75 9.7 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain CBFD_NFYB_HMF PF00808.18 EEQ30971.1 - 5.1e-06 26.4 0.2 1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.5 EEQ30971.1 - 0.81 8.6 25.2 1.1 8.2 17.4 1.2 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EEQ30971.1 - 2.4 6.5 28.0 3.3 6.0 19.4 1.2 1 0 0 1 1 1 0 Daxx Family SIR2 PF02146.12 EEQ30972.1 - 1.2e-26 93.5 0.0 4.1e-26 91.8 0.0 1.9 2 1 0 2 2 2 1 Sir2 family FAD_binding_4 PF01565.18 EEQ30972.1 - 0.0077 15.7 0.0 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Peptidase_U49 PF10463.4 EEQ30972.1 - 0.13 11.9 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase U49 Med16 PF11635.3 EEQ30973.1 - 2.9e-160 534.7 0.0 3.5e-160 534.5 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ribosomal_L29 PF00831.18 EEQ30974.1 - 6.8e-18 64.1 0.2 6.8e-18 64.1 0.1 1.9 2 1 0 2 2 2 1 Ribosomal L29 protein SPATA24 PF15175.1 EEQ30974.1 - 0.063 12.9 1.4 0.084 12.5 1.0 1.3 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 Cortex-I_coil PF09304.5 EEQ30974.1 - 0.2 11.7 5.6 0.083 12.9 1.5 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil FliT PF05400.8 EEQ30974.1 - 0.5 10.8 4.2 2.2 8.7 0.1 2.3 2 1 0 2 2 2 0 Flagellar protein FliT V-SNARE_C PF12352.3 EEQ30975.1 - 6.7e-14 51.7 8.1 1.1e-13 51.0 0.2 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.1 EEQ30975.1 - 0.0071 14.8 6.4 0.0097 14.4 4.5 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Sec20 PF03908.8 EEQ30975.1 - 0.014 15.1 2.5 4.5 7.0 0.0 3.3 2 1 2 4 4 4 0 Sec20 AAA_13 PF13166.1 EEQ30975.1 - 0.061 11.7 1.0 0.063 11.7 0.7 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 EEQ30975.1 - 0.064 11.9 3.1 0.11 11.1 2.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Het-C PF07217.6 EEQ30975.1 - 0.077 11.1 0.3 0.95 7.5 0.0 1.9 1 1 1 2 2 2 0 Heterokaryon incompatibility protein Het-C Dor1 PF04124.7 EEQ30975.1 - 0.14 10.5 6.5 0.22 9.9 4.5 1.3 1 0 0 1 1 1 0 Dor1-like family MtrG PF04210.8 EEQ30975.1 - 0.2 11.3 0.5 0.46 10.1 0.3 1.7 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G TBPIP PF07106.8 EEQ30975.1 - 0.25 10.8 5.1 0.36 10.3 3.1 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4570 PF15134.1 EEQ30975.1 - 0.32 10.8 4.5 0.66 9.8 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) IncA PF04156.9 EEQ30975.1 - 0.32 10.5 9.8 0.76 9.3 6.8 1.7 1 0 0 1 1 1 0 IncA protein Syntaxin-6_N PF09177.6 EEQ30975.1 - 0.33 11.3 6.3 0.58 10.5 2.5 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DivIC PF04977.10 EEQ30975.1 - 0.37 10.3 7.2 3.9 7.0 0.7 3.3 3 1 1 4 4 4 0 Septum formation initiator APG6 PF04111.7 EEQ30975.1 - 0.37 9.7 4.7 0.56 9.2 3.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EEQ30975.1 - 0.37 9.9 6.0 0.6 9.2 4.1 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATP-synt_10 PF05176.9 EEQ30976.1 - 1.2e-81 273.7 0.0 1.5e-81 273.3 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.1 EEQ30977.1 - 6.1e-31 106.7 0.0 1.3e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EEQ30977.1 - 1.2e-19 69.7 0.0 2.6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EEQ30977.1 - 1.4e-17 62.9 1.1 1.4e-17 62.9 0.8 2.4 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EEQ30977.1 - 1.7e-16 60.1 0.1 8e-16 57.9 0.1 2.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain BRCT PF00533.21 EEQ30977.1 - 0.042 13.9 0.1 1.6 8.9 0.0 3.0 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 EEQ30977.1 - 0.092 13.0 0.5 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 Nucleotidyltransferase domain Zn_clus PF00172.13 EEQ30978.1 - 0.011 15.5 8.8 0.027 14.3 6.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.10 EEQ30978.1 - 0.034 13.9 0.3 0.081 12.6 0.2 1.7 1 0 0 1 1 1 0 BED zinc finger CPL PF08144.6 EEQ30980.1 - 1.4e-15 57.4 0.0 7.5e-15 55.0 0.0 2.4 2 0 0 2 2 2 1 CPL (NUC119) domain DUF2890 PF11081.3 EEQ30980.1 - 0.0051 16.8 12.3 0.013 15.5 8.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) Nop14 PF04147.7 EEQ30980.1 - 1.4 6.7 25.2 2 6.2 17.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EEQ30980.1 - 7.7 4.4 16.5 13 3.6 11.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Rad51 PF08423.6 EEQ30983.1 - 2.5e-138 459.1 0.0 3.2e-138 458.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEQ30983.1 - 6.9e-13 48.4 0.0 9.9e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EEQ30983.1 - 3e-07 30.4 0.2 1.1e-06 28.7 0.2 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EEQ30983.1 - 6.9e-07 28.6 0.0 9.2e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EEQ30983.1 - 2.4e-05 23.5 0.1 6e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 KaiC HHH PF00633.18 EEQ30983.1 - 0.017 14.8 0.5 6.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif DnaB_C PF03796.10 EEQ30983.1 - 0.038 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EEQ30983.1 - 0.045 12.5 0.1 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.3 EEQ30984.1 - 7.6e-131 436.9 7.4 1.1e-130 436.4 5.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_12 PF13424.1 EEQ30984.1 - 0.036 14.0 0.8 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ30984.1 - 0.072 12.9 0.2 0.44 10.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ30984.1 - 0.2 12.3 1.7 0.47 11.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.4 EEQ30985.1 - 8.1e-123 410.4 0.0 3.8e-120 401.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.8 EEQ30986.1 - 2.8e-23 81.4 12.1 3.6e-23 81.1 8.4 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.14 EEQ30987.1 - 4.7e-148 492.8 0.3 5.3e-148 492.6 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase zf-H2C2_2 PF13465.1 EEQ30988.1 - 1.2e-08 34.8 8.5 2.8e-07 30.5 0.4 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ30988.1 - 1.4e-07 31.4 6.2 4.6e-05 23.4 0.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ30988.1 - 6.6e-05 22.9 7.4 0.00042 20.4 0.2 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ30988.1 - 0.0027 17.5 0.2 1.2 9.1 0.0 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ30988.1 - 0.36 11.0 6.1 1.2 9.4 0.3 3.5 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SNF2_N PF00176.18 EEQ30989.1 - 3.6e-64 216.4 0.0 6.7e-64 215.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EEQ30989.1 - 2.3e-23 81.5 0.3 2.9e-13 49.2 0.0 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EEQ30989.1 - 3.8e-18 65.5 0.0 3.2e-17 62.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EEQ30989.1 - 1.1e-11 44.3 0.0 3.3e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ30989.1 - 2.6e-06 27.3 0.0 6.3e-05 22.8 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEQ30989.1 - 0.0041 17.2 0.0 0.02 15.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain DUF3972 PF13118.1 EEQ30989.1 - 0.016 15.2 0.7 0.044 13.8 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) ABC_tran PF00005.22 EEQ30990.1 - 5.9e-34 117.2 0.0 1.4e-15 57.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EEQ30990.1 - 1.8e-14 53.0 5.6 1.8e-14 53.0 3.8 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EEQ30990.1 - 8.8e-13 48.8 2.7 0.064 13.2 0.0 4.6 3 2 2 5 5 4 4 AAA domain SMC_N PF02463.14 EEQ30990.1 - 1.6e-11 43.8 2.7 0.0024 17.1 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EEQ30990.1 - 1.5e-06 27.5 0.1 1.5 7.7 0.0 4.4 4 1 0 5 5 5 1 AAA ATPase domain AAA PF00004.24 EEQ30990.1 - 2.3e-05 24.6 0.1 0.042 14.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EEQ30990.1 - 4.1e-05 23.0 0.5 0.056 12.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ30990.1 - 4.1e-05 24.3 0.8 0.55 11.0 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEQ30990.1 - 4.9e-05 23.4 0.0 0.022 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EEQ30990.1 - 6.1e-05 21.8 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Fer4 PF00037.22 EEQ30990.1 - 6.5e-05 22.3 2.5 6.5e-05 22.3 1.7 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_18 PF13238.1 EEQ30990.1 - 0.00049 20.3 0.2 0.33 11.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EEQ30990.1 - 0.00049 19.8 1.7 0.079 12.6 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EEQ30990.1 - 0.00059 19.0 3.1 0.72 9.0 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 VirE PF05272.6 EEQ30990.1 - 0.00077 18.9 0.2 0.97 8.8 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E SRP54 PF00448.17 EEQ30990.1 - 0.0011 18.4 3.1 0.024 14.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EEQ30990.1 - 0.0014 18.2 0.5 0.013 15.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EEQ30990.1 - 0.0014 18.7 0.6 0.61 10.2 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.1 EEQ30990.1 - 0.0015 18.3 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 EEQ30990.1 - 0.0027 17.5 11.7 0.0051 16.6 8.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EEQ30990.1 - 0.0033 17.2 11.0 0.0082 15.9 1.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_25 PF13481.1 EEQ30990.1 - 0.0036 16.7 0.1 1.7 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEQ30990.1 - 0.0037 16.9 1.8 0.4 10.3 0.0 2.6 3 0 0 3 3 2 1 NACHT domain AAA_23 PF13476.1 EEQ30990.1 - 0.0049 17.2 0.7 0.26 11.5 0.2 2.4 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EEQ30990.1 - 0.0049 16.2 0.2 2.6 7.3 0.0 2.9 3 0 0 3 3 3 1 Thymidylate kinase Miro PF08477.8 EEQ30990.1 - 0.0084 16.6 0.1 0.63 10.5 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein Fer4_10 PF13237.1 EEQ30990.1 - 0.014 15.2 1.5 0.014 15.2 1.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_16 PF13191.1 EEQ30990.1 - 0.025 14.5 0.4 5.6 6.9 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 EEQ30990.1 - 0.031 13.1 0.5 9.2 5.0 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain Fer4_7 PF12838.2 EEQ30990.1 - 0.033 14.5 1.8 0.033 14.5 1.3 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain AAA_5 PF07728.9 EEQ30990.1 - 0.036 13.7 0.2 2 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EEQ30990.1 - 0.046 13.6 0.1 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 EEQ30990.1 - 0.047 14.4 0.1 0.047 14.4 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain SbcCD_C PF13558.1 EEQ30990.1 - 0.051 13.4 0.1 9.4 6.2 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EEQ30990.1 - 0.058 11.8 0.5 0.12 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEQ30990.1 - 0.063 12.8 0.4 0.89 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 EEQ30990.1 - 0.068 13.2 8.1 0.22 11.5 5.7 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_24 PF13479.1 EEQ30990.1 - 0.092 12.3 1.7 0.85 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EEQ30990.1 - 0.11 11.5 0.2 0.25 10.4 0.1 1.5 1 0 0 1 1 1 0 KaiC Fer4_17 PF13534.1 EEQ30990.1 - 0.13 12.5 0.2 0.13 12.5 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain T2SE PF00437.15 EEQ30990.1 - 0.17 10.7 0.6 0.98 8.2 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein PduV-EutP PF10662.4 EEQ30990.1 - 0.18 11.2 2.9 0.18 11.2 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EEQ30990.1 - 0.23 11.1 2.6 7 6.3 0.1 2.7 2 0 0 2 2 2 0 NTPase Fer4_9 PF13187.1 EEQ30990.1 - 0.74 10.1 13.8 0.043 14.0 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EEQ30990.1 - 1 9.4 12.8 0.47 10.4 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.14 EEQ30991.1 - 3.8e-56 186.8 16.7 9.4e-14 51.1 0.0 7.0 6 1 0 6 6 6 5 FF domain WW PF00397.21 EEQ30991.1 - 8.5e-19 67.0 10.4 1.3e-09 37.6 0.4 2.6 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 EEQ30992.1 - 8.9e-84 281.3 0.4 1.3e-83 280.8 0.3 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 RuvB_N PF05496.7 EEQ30992.1 - 0.05 12.6 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mpv17_PMP22 PF04117.7 EEQ30993.1 - 1.2e-21 76.0 0.1 3.1e-21 74.7 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 EEQ30994.1 - 2.1e-23 82.6 27.1 1.4e-22 79.9 16.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.4 EEQ30994.1 - 0.15 12.0 2.3 0.43 10.5 1.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) p450 PF00067.17 EEQ30995.1 - 7.8e-61 205.9 0.0 8.8e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.16 EEQ30996.1 - 4.9e-97 325.5 0.0 6.2e-97 325.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Arm PF00514.18 EEQ30997.1 - 8.5e-93 301.4 8.4 7.1e-14 51.0 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEQ30997.1 - 2.6e-26 91.7 0.0 5.3e-10 39.4 0.0 5.5 1 1 6 7 7 7 5 HEAT repeats IBB PF01749.15 EEQ30997.1 - 2.7e-22 78.7 1.0 4.9e-22 77.8 0.7 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EEQ30997.1 - 9.9e-20 68.8 0.1 7.4e-06 25.6 0.0 6.7 7 0 0 7 7 6 4 HEAT repeat HEAT_EZ PF13513.1 EEQ30997.1 - 1.5e-19 69.8 6.8 5.9e-09 36.1 0.0 6.1 4 1 3 7 7 7 3 HEAT-like repeat Arm_2 PF04826.8 EEQ30997.1 - 1.4e-09 37.4 0.0 0.0027 16.8 0.0 3.7 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EEQ30997.1 - 9.7e-06 24.1 0.0 0.0023 16.3 0.0 2.9 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EEQ30997.1 - 0.00012 22.0 0.0 4.8 7.1 0.0 4.5 3 2 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.11 EEQ30997.1 - 0.00044 20.4 0.6 0.8 10.3 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 EEQ30997.1 - 0.0057 16.5 0.3 2.4 8.1 0.0 4.0 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 EEQ30997.1 - 0.0062 14.8 0.1 0.19 9.9 0.0 2.6 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit Atx10homo_assoc PF09759.4 EEQ30997.1 - 0.096 12.4 0.0 13 5.5 0.0 3.3 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain POT1 PF02765.12 EEQ30998.1 - 1.1e-13 51.2 0.0 1.4e-11 44.4 0.0 2.5 2 1 0 2 2 2 2 Telomeric single stranded DNA binding POT1/CDC13 YaaC PF14175.1 EEQ30999.1 - 0.0068 15.4 0.2 0.01 14.7 0.2 1.2 1 0 0 1 1 1 1 YaaC-like Protein Pneumo_att_G PF05539.6 EEQ30999.1 - 0.048 13.0 7.4 0.068 12.5 5.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G TRAP_alpha PF03896.11 EEQ31000.1 - 1.1e-13 50.9 0.0 4.5e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit HA2 PF04408.18 EEQ31001.1 - 5.1e-19 68.1 0.1 5.1e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEQ31001.1 - 2.8e-16 59.3 0.0 5.7e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEQ31001.1 - 1.5e-11 43.9 0.0 3.9e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ31001.1 - 1.6e-11 44.0 0.1 3.2e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.17 EEQ31001.1 - 1.7e-11 43.9 0.1 3.7e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.1 EEQ31001.1 - 0.00044 20.3 0.1 0.0015 18.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain UBA PF00627.26 EEQ31001.1 - 0.0092 15.7 0.2 2.1 8.3 0.0 3.2 3 0 0 3 3 3 1 UBA/TS-N domain DND1_DSRM PF14709.1 EEQ31001.1 - 0.012 15.8 0.0 0.04 14.1 0.0 2.0 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 T2SE PF00437.15 EEQ31001.1 - 0.013 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EEQ31001.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 EEQ31001.1 - 0.016 14.7 0.0 0.083 12.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EEQ31001.1 - 0.028 13.8 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rap1_C PF11626.3 EEQ31001.1 - 0.044 13.6 0.0 0.56 10.1 0.0 2.6 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Tox-WTIP PF15654.1 EEQ31002.1 - 3.8 7.2 5.8 27 4.4 0.1 3.2 3 0 0 3 3 3 0 Toxin with a conserved tryptophan and TIP tripeptide motif Arylsulfotran_2 PF14269.1 EEQ31003.1 - 4.9e-119 396.9 0.1 6.6e-119 396.4 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EEQ31003.1 - 1.4e-15 56.8 0.0 2.1e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Tub_2 PF04525.7 EEQ31003.1 - 0.027 13.8 0.0 0.087 12.2 0.0 1.8 1 0 0 1 1 1 0 Tubby C 2 RasGEF PF00617.14 EEQ31004.1 - 1.3e-63 214.1 0.1 2.3e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEQ31004.1 - 6.8e-25 87.1 0.1 1.4e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EEQ31004.1 - 1.6e-13 49.8 0.1 2.9e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ31004.1 - 4.2e-11 42.2 0.2 8.7e-11 41.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ31004.1 - 5.2e-10 38.6 0.1 1.2e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EEQ31004.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 WW domain RHH_1 PF01402.16 EEQ31004.1 - 0.14 12.0 2.1 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HGTP_anticodon PF03129.15 EEQ31005.1 - 0.058 13.3 0.3 0.09 12.7 0.2 1.2 1 0 0 1 1 1 0 Anticodon binding domain Fungal_trans PF04082.13 EEQ31006.1 - 7.7e-20 70.8 3.8 1.2e-19 70.1 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EEQ31006.1 - 4.3e-07 29.9 14.3 9.7e-05 22.4 4.0 3.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ31006.1 - 0.00041 20.4 15.2 0.037 14.3 4.9 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ31006.1 - 0.00068 19.8 16.7 0.18 12.2 5.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-CHY PF05495.7 EEQ31006.1 - 0.55 10.4 6.3 0.11 12.7 1.6 1.8 2 0 0 2 2 2 0 CHY zinc finger UPRTase PF14681.1 EEQ31007.1 - 1.4e-70 236.7 0.0 1.6e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEQ31007.1 - 4.3e-07 29.6 0.0 1.3e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.10 EEQ31008.1 - 2.9e-24 85.1 19.7 7.2e-13 48.4 0.5 4.0 4 1 0 4 4 4 3 CrcB-like protein JAB PF01398.16 EEQ31009.1 - 9.6e-27 92.9 0.1 1.7e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EEQ31009.1 - 2.9e-05 23.5 0.0 7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.20 EEQ31010.1 - 6.8e-21 74.5 0.0 1e-20 73.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31010.1 - 8.9e-17 60.9 0.0 1.7e-16 60.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ31010.1 - 0.0041 16.1 0.1 0.0073 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEQ31010.1 - 0.024 14.2 0.0 0.053 13.0 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EEQ31010.1 - 0.028 13.7 0.1 2.3 7.5 0.1 2.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EEQ31010.1 - 0.14 11.0 0.0 0.51 9.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like MAP65_ASE1 PF03999.7 EEQ31011.1 - 2.4e-71 241.1 16.5 4.5e-70 236.9 11.0 2.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF1140 PF06600.6 EEQ31011.1 - 0.042 13.9 1.5 0.057 13.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) Spectrin PF00435.16 EEQ31011.1 - 0.044 14.0 12.3 0.33 11.2 0.5 4.0 2 1 1 3 3 3 0 Spectrin repeat TMF_TATA_bd PF12325.3 EEQ31011.1 - 0.39 10.4 24.3 0.34 10.6 5.1 4.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding tRNA-synt_1c PF00749.16 EEQ31012.1 - 1.1e-94 316.6 0.0 1.5e-94 316.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain CTDII PF01556.13 EEQ31013.1 - 4.2e-25 87.4 0.5 6e-20 70.9 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EEQ31013.1 - 2.2e-23 81.7 3.4 4e-23 80.9 2.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEQ31013.1 - 1.2e-12 47.7 17.6 2.1e-12 46.8 12.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EEQ31013.1 - 0.064 12.9 5.2 0.78 9.4 0.4 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EEQ31013.1 - 0.47 10.8 4.4 1 9.7 3.0 1.6 1 0 0 1 1 1 0 Cytochrome c3 Stc1 PF12898.2 EEQ31013.1 - 1.5 8.9 11.0 1.2e+03 -0.4 7.6 2.4 1 1 0 1 1 1 0 Stc1 domain GCC2_GCC3 PF07699.8 EEQ31013.1 - 4.1 7.0 12.1 6.8 6.3 1.6 2.5 2 0 0 2 2 2 0 GCC2 and GCC3 4HBT PF03061.17 EEQ31014.1 - 1.9e-11 43.8 0.0 3.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EEQ31014.1 - 0.00012 22.5 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 EEQ31014.1 - 0.00048 19.1 0.2 0.0006 18.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase PseudoU_synth_2 PF00849.17 EEQ31015.1 - 2.5e-26 92.4 0.0 4e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.7 EEQ31015.1 - 0.0019 17.8 0.1 0.005 16.5 0.0 1.7 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_L32e PF01655.13 EEQ31016.1 - 8.3e-35 119.1 0.6 8.3e-35 119.1 0.4 2.0 1 1 1 2 2 2 1 Ribosomal protein L32 Sec2p PF06428.6 EEQ31016.1 - 1.3e-10 40.9 11.9 1.3e-10 40.9 8.3 1.7 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.3 EEQ31016.1 - 0.0024 15.3 6.8 0.0024 15.3 4.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) CAF-1_p150 PF11600.3 EEQ31016.1 - 0.007 15.7 16.3 0.007 15.7 11.3 2.3 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mo25 PF08569.6 EEQ31016.1 - 0.044 12.8 1.9 3.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Mo25-like HSBP1 PF06825.7 EEQ31016.1 - 0.05 13.1 1.9 0.63 9.6 0.3 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Atg14 PF10186.4 EEQ31016.1 - 0.099 11.5 18.7 0.25 10.2 4.7 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2072 PF09845.4 EEQ31016.1 - 0.19 11.6 0.0 0.19 11.6 0.0 2.5 2 1 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Macoilin PF09726.4 EEQ31016.1 - 0.22 9.7 17.8 0.3 9.3 12.3 1.1 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 EEQ31016.1 - 0.94 9.8 13.8 0.93 9.9 0.8 3.6 2 1 1 3 3 3 0 SlyX RAP1 PF07218.6 EEQ31016.1 - 1.3 7.0 5.4 1.7 6.6 3.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF342 PF03961.8 EEQ31016.1 - 1.3 7.3 6.7 0.36 9.1 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) RRM_1 PF00076.17 EEQ31017.1 - 3.7e-15 55.3 0.0 6.8e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31017.1 - 5.9e-14 51.7 0.0 9.5e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ31017.1 - 4.9e-06 26.2 0.0 8.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XH PF03469.9 EEQ31018.1 - 0.14 11.7 0.3 0.26 10.9 0.2 1.4 1 1 0 1 1 1 0 XH domain Tim17 PF02466.14 EEQ31018.1 - 0.32 11.0 6.7 4.3 7.4 0.3 2.2 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family 2-Hacid_dh_C PF02826.14 EEQ31019.1 - 5.7e-56 188.4 0.0 7.5e-56 188.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ31019.1 - 8e-15 54.4 0.0 1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEQ31019.1 - 8.2e-07 28.9 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EEQ31019.1 - 0.0053 17.2 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EEQ31019.1 - 0.016 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DcpS_C PF11969.3 EEQ31020.1 - 5.4e-15 55.6 0.7 5.5e-14 52.3 0.5 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EEQ31020.1 - 4.6e-12 46.3 0.3 1.4e-11 44.7 0.2 1.8 1 1 0 1 1 1 1 HIT domain Cyclin_N PF00134.18 EEQ31021.1 - 8e-43 145.0 0.7 1.7e-42 144.0 0.5 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEQ31021.1 - 7.6e-32 109.7 0.0 2.3e-31 108.1 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF433 PF04255.9 EEQ31021.1 - 0.11 11.9 0.1 0.33 10.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Zn_clus PF00172.13 EEQ31022.1 - 0.00065 19.5 12.6 0.0014 18.5 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EEQ31022.1 - 0.045 12.9 0.5 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Histone chaperone domain CHZ RNA_pol_Rpc4 PF05132.9 EEQ31023.1 - 2.9e-30 104.9 0.0 2.9e-30 104.9 0.0 2.6 3 1 0 3 3 3 1 RNA polymerase III RPC4 Fmp27 PF10344.4 EEQ31025.1 - 2.7e-178 594.4 0.0 5.6e-178 593.4 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EEQ31025.1 - 8.6e-159 529.2 0.2 1.7e-158 528.2 0.1 1.5 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EEQ31025.1 - 8.9e-142 472.8 0.0 1.8e-141 471.8 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EEQ31025.1 - 1.4e-52 177.6 0.0 3.5e-52 176.4 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EEQ31025.1 - 2.3e-51 173.6 0.2 9.9e-51 171.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EEQ31025.1 - 1.7e-26 92.6 0.0 6.3e-26 90.7 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain PH_7 PF15408.1 EEQ31025.1 - 0.025 14.4 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Corona_M PF01635.13 EEQ31026.1 - 0.92 8.4 6.6 0.32 9.9 2.6 1.6 1 1 0 1 1 1 0 Coronavirus M matrix/glycoprotein B-block_TFIIIC PF04182.7 EEQ31027.1 - 1.5e-20 72.8 0.1 3.1e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EEQ31027.1 - 0.0074 15.9 1.4 0.021 14.5 0.0 2.4 3 0 0 3 3 3 1 MarR family UQ_con PF00179.21 EEQ31028.1 - 7.5e-22 77.2 0.0 1.2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rubredoxin PF00301.15 EEQ31028.1 - 0.04 13.8 0.1 0.082 12.7 0.1 1.5 1 0 0 1 1 1 0 Rubredoxin Prok-E2_B PF14461.1 EEQ31028.1 - 0.041 13.6 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family B RWD PF05773.17 EEQ31028.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain zf-DHHC PF01529.15 EEQ31029.1 - 1.4e-39 135.3 10.8 1.4e-39 135.3 7.5 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Rhomboid PF01694.17 EEQ31030.1 - 1.6e-35 122.3 9.6 1.6e-35 122.3 6.7 2.2 3 0 0 3 3 3 1 Rhomboid family TFIIE-A_C-term PF11521.3 EEQ31030.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha DUF4231 PF14015.1 EEQ31030.1 - 0.18 11.8 1.7 3.7 7.5 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) GST_C_3 PF14497.1 EEQ31031.1 - 0.0001 22.6 0.0 0.00017 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ31031.1 - 0.00053 19.8 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ31031.1 - 0.00061 19.9 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ31031.1 - 0.056 13.4 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Kinetochor_Ybp2 PF08568.5 EEQ31032.1 - 2.3e-124 415.9 0.1 2.7e-124 415.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DUF3317 PF11779.3 EEQ31033.1 - 0.0017 17.7 2.3 0.0026 17.1 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) PLDc_2 PF13091.1 EEQ31035.1 - 1.1e-14 54.2 0.0 3.1e-06 26.9 0.0 3.5 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EEQ31035.1 - 3.2e-12 45.8 0.9 1.2e-05 24.9 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EEQ31035.1 - 0.091 11.7 0.1 0.58 9.0 0.0 2.1 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB GFA PF04828.9 EEQ31036.1 - 2e-19 69.2 1.7 3.3e-19 68.5 1.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cyanate_lyase PF02560.9 EEQ31037.1 - 4.4e-32 109.4 0.0 7.1e-32 108.7 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 EEQ31037.1 - 6.8e-05 22.9 0.0 9.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 EEQ31037.1 - 0.00029 20.9 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.17 EEQ31037.1 - 0.0026 17.5 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix DUF3521 PF12035.3 EEQ31037.1 - 0.065 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3521) zf-C2H2_4 PF13894.1 EEQ31038.1 - 3.4e-09 36.3 12.9 0.48 10.8 0.1 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ31038.1 - 7.6e-08 32.2 20.1 0.053 13.8 0.1 6.2 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.2 EEQ31038.1 - 0.0001 22.3 16.6 0.02 15.1 0.1 5.1 6 0 0 6 6 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ31038.1 - 0.00025 21.0 10.6 0.04 14.0 0.1 4.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ31038.1 - 0.0069 16.2 9.5 0.21 11.5 0.0 4.5 5 0 0 5 5 5 2 C2H2-type zinc finger Rad50_zn_hook PF04423.9 EEQ31038.1 - 0.015 14.7 2.3 1.5 8.3 0.1 3.3 3 1 1 4 4 4 0 Rad50 zinc hook motif zinc_ribbon_4 PF13717.1 EEQ31038.1 - 0.26 11.0 9.0 14 5.4 0.5 4.0 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 EEQ31038.1 - 0.27 11.3 19.0 1.3 9.2 2.0 4.2 2 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_5 PF13719.1 EEQ31038.1 - 0.5 9.9 9.3 19 4.9 0.1 4.0 3 1 0 3 3 3 0 zinc-ribbon domain zf-CSL PF05207.8 EEQ31038.1 - 4.6 6.8 11.3 3.2 7.3 0.2 2.7 2 1 0 2 2 2 0 CSL zinc finger zf-Di19 PF05605.7 EEQ31038.1 - 8.3 6.6 21.9 5.6 7.1 0.2 4.9 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding M16C_assoc PF08367.6 EEQ31040.1 - 0.00025 19.9 2.3 0.11 11.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16C associated DUF2390 PF09523.5 EEQ31040.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2390) MFS_1 PF07690.11 EEQ31041.1 - 3.3e-41 141.1 47.7 7.5e-40 136.7 28.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EEQ31042.1 - 1.4e-17 63.8 0.0 6e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EEQ31042.1 - 1.6e-06 27.4 0.2 0.00023 20.3 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.19 EEQ31042.1 - 2.7e-06 26.5 0.2 1.5e-05 24.0 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ31042.1 - 2.8e-05 24.0 0.0 7.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ31042.1 - 0.00015 21.7 0.1 0.00037 20.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEQ31042.1 - 0.00016 20.7 0.0 0.00032 19.6 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EEQ31042.1 - 0.00032 19.2 0.0 0.00065 18.2 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EEQ31042.1 - 0.00037 20.8 0.0 0.00077 19.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEQ31042.1 - 0.0057 15.3 0.0 0.29 9.7 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase DUF1517 PF07466.6 EEQ31042.1 - 0.0059 15.6 0.0 0.0092 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) 3HCDH_N PF02737.13 EEQ31042.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 EEQ31042.1 - 0.025 13.4 0.0 0.069 11.9 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.19 EEQ31042.1 - 0.051 12.4 0.1 0.16 10.8 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain DNA_pol_B PF00136.16 EEQ31043.1 - 2.6e-145 484.7 4.7 3.6e-145 484.3 3.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EEQ31043.1 - 1.2e-83 280.7 0.2 2.6e-83 279.6 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EEQ31043.1 - 1.1e-24 86.2 2.7 2.7e-24 84.9 1.9 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EEQ31043.1 - 3.1e-05 23.8 0.1 0.00011 22.0 0.1 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EEQ31043.1 - 0.00073 19.1 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 EEQ31043.1 - 0.018 14.7 6.4 0.084 12.6 0.6 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_hydro_31 PF01055.21 EEQ31043.1 - 0.022 13.6 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Fungal_trans_2 PF11951.3 EEQ31044.1 - 1.4e-10 40.3 1.8 1.4e-10 40.3 1.2 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ31044.1 - 4e-08 33.0 9.6 7.2e-08 32.2 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EEQ31045.1 - 1.1e-33 116.5 0.0 5.3e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31045.1 - 1.9e-13 50.1 0.0 1.9e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ31045.1 - 0.24 10.3 0.0 5.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Glyco_hydro_47 PF01532.15 EEQ31046.1 - 2e-175 583.8 0.0 2.3e-175 583.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 LIP PF03583.9 EEQ31047.1 - 4e-76 256.0 0.1 4.9e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EEQ31047.1 - 0.0032 17.3 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Syja_N PF02383.13 EEQ31048.1 - 1.9e-90 302.8 0.1 3.3e-90 302.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Nudix_N PF12535.3 EEQ31048.1 - 0.044 13.2 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF2454 PF10521.4 EEQ31049.1 - 1e-82 277.3 1.6 1.5e-82 276.8 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EEQ31050.1 - 2e-23 82.9 0.1 4.2e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EEQ31050.1 - 3e-06 26.7 0.0 6.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EEQ31050.1 - 0.0035 17.1 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Glyco_transf_8C PF08437.5 EEQ31050.1 - 0.11 12.4 0.1 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal TRAPPC-Trs85 PF12739.2 EEQ31051.1 - 3.9e-121 404.5 0.3 9.8e-119 396.6 0.0 2.1 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF3503 PF12011.3 EEQ31051.1 - 0.14 11.9 0.1 0.65 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3503) Snf7 PF03357.16 EEQ31054.1 - 1e-17 64.0 11.9 1e-17 64.0 8.2 1.7 1 1 1 2 2 2 1 Snf7 DUF1729 PF08354.5 EEQ31054.1 - 0.13 12.0 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Prefoldin_2 PF01920.15 EEQ31054.1 - 1 9.1 14.5 5.8 6.7 0.1 2.8 2 1 0 2 2 2 0 Prefoldin subunit DUF948 PF06103.6 EEQ31054.1 - 6.3 6.7 7.2 8 6.4 0.6 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 EEQ31054.1 - 9.8 6.6 11.0 0.69 10.3 0.1 3.7 2 1 2 4 4 4 0 SlyX zf-C3HC4_2 PF13923.1 EEQ31055.1 - 2.1e-07 30.8 17.6 2.1e-07 30.8 12.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EEQ31055.1 - 1.3e-06 28.0 7.8 1.3e-06 28.0 5.4 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 EEQ31055.1 - 2.4e-06 27.0 16.7 2.4e-06 27.0 11.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ31055.1 - 4.3e-06 26.3 16.4 4.3e-06 26.3 11.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ31055.1 - 4.8e-06 26.1 13.8 4.8e-06 26.1 9.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ31055.1 - 4.9e-06 26.2 21.2 8.4e-06 25.5 11.1 2.3 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.22 EEQ31055.1 - 2.3e-05 23.7 0.0 4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 EEQ31055.1 - 0.00068 19.4 16.7 0.00068 19.4 11.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ31055.1 - 0.0031 17.1 8.6 0.0031 17.1 6.0 2.6 2 1 0 2 2 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.9 EEQ31055.1 - 0.018 14.5 9.9 0.26 10.7 0.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif Mob_synth_C PF06463.8 EEQ31055.1 - 0.039 13.6 5.5 0.092 12.4 3.8 1.6 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-Apc11 PF12861.2 EEQ31055.1 - 0.068 13.0 3.7 0.16 11.8 2.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 EEQ31055.1 - 0.072 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.2 EEQ31055.1 - 0.31 11.1 9.7 0.18 11.9 5.1 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger zf-Nse PF11789.3 EEQ31055.1 - 5.6 6.5 13.6 0.7 9.4 6.0 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit CDC27 PF09507.5 EEQ31056.1 - 2.2e-86 290.7 28.3 3.2e-86 290.2 19.6 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 EEQ31057.1 - 1.9e-180 600.0 0.0 2.2e-180 599.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) TaqI_C PF12950.2 EEQ31057.1 - 0.03 14.0 0.0 0.096 12.4 0.0 1.8 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain RRM_1 PF00076.17 EEQ31058.1 - 0.0037 16.8 0.0 0.61 9.7 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31058.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NMD3 PF04981.8 EEQ31059.1 - 5.5e-74 248.2 3.8 7.6e-74 247.7 2.6 1.2 1 0 0 1 1 1 1 NMD3 family FYVE PF01363.16 EEQ31059.1 - 1.2 9.1 9.2 5 7.1 4.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger HypA PF01155.14 EEQ31059.1 - 2.5 7.8 10.2 2.8 7.6 0.9 3.0 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EEQ31059.1 - 9.6 6.1 11.6 1.5e+02 2.3 0.0 2.8 2 1 0 2 2 2 0 Double zinc ribbon Oligomerisation PF02410.10 EEQ31060.1 - 0.00039 20.3 0.0 0.38 10.8 0.1 2.9 2 0 0 2 2 2 2 Oligomerisation domain Pex2_Pex12 PF04757.9 EEQ31061.1 - 9.7e-55 185.4 1.7 1.4e-54 184.9 1.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EEQ31061.1 - 3.3e-07 30.0 2.9 5.8e-07 29.2 2.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EEQ31061.1 - 6.4e-07 29.2 3.5 1.1e-06 28.5 1.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ31061.1 - 0.0042 16.7 2.1 0.0079 15.8 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ31061.1 - 0.0044 16.8 3.2 0.0095 15.7 2.2 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ31061.1 - 0.14 11.8 0.7 0.27 10.9 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.22 EEQ31062.1 - 8.5e-60 198.4 0.2 1.3e-20 72.8 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein WAC_Acf1_DNA_bd PF10537.4 EEQ31063.1 - 1.6e-41 140.6 0.5 5.6e-41 138.8 0.4 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EEQ31063.1 - 2.1e-19 69.0 2.2 4e-19 68.1 1.5 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EEQ31063.1 - 6.4e-12 44.8 0.4 1.6e-11 43.6 0.3 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EEQ31063.1 - 4.7e-05 23.0 0.2 0.00012 21.8 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 EEQ31063.1 - 0.00033 20.4 0.1 0.0011 18.7 0.0 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Alg6_Alg8 PF03155.10 EEQ31064.1 - 6.8e-139 463.7 28.4 8.8e-139 463.3 19.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 EEQ31065.1 - 7.5e-21 74.3 0.0 1.1e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family WXG100 PF06013.7 EEQ31065.1 - 0.0025 17.7 0.2 0.1 12.6 0.0 2.4 2 0 0 2 2 2 1 Proteins of 100 residues with WXG TBPIP PF07106.8 EEQ31065.1 - 0.0069 15.9 3.3 0.011 15.3 2.3 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 EEQ31065.1 - 0.015 15.0 3.8 0.023 14.3 2.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ALMT PF11744.3 EEQ31065.1 - 0.059 12.0 0.4 0.083 11.5 0.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1759 PF03564.10 EEQ31065.1 - 0.075 12.8 0.4 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) FAM196 PF15265.1 EEQ31065.1 - 0.11 11.7 3.9 0.14 11.3 2.7 1.1 1 0 0 1 1 1 0 FAM196 family APG6 PF04111.7 EEQ31065.1 - 0.18 10.8 1.9 0.26 10.3 1.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin PF00804.20 EEQ31065.1 - 0.3 11.2 6.7 0.94 9.6 4.6 1.8 1 1 0 1 1 1 0 Syntaxin IncA PF04156.9 EEQ31065.1 - 0.47 10.0 4.3 0.89 9.1 3.0 1.4 1 0 0 1 1 1 0 IncA protein Syntaxin-6_N PF09177.6 EEQ31065.1 - 0.67 10.3 4.1 11 6.5 0.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Snapin_Pallidin PF14712.1 EEQ31065.1 - 0.74 10.1 5.4 1.4 9.2 3.8 1.5 1 0 0 1 1 1 0 Snapin/Pallidin TMF_DNA_bd PF12329.3 EEQ31065.1 - 1.1 9.1 4.7 7.9 6.3 3.2 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 EEQ31065.1 - 1.4 9.1 4.5 9.1 6.6 0.4 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.19 EEQ31065.1 - 1.5 8.4 8.0 5.6 6.6 1.0 2.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD PHD PF00628.24 EEQ31066.1 - 5.9e-18 64.2 17.1 1.1e-11 44.2 5.5 2.5 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 EEQ31066.1 - 0.0015 17.8 5.5 0.41 9.9 1.6 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.1 EEQ31066.1 - 0.4 10.8 4.5 1.3 9.1 1.1 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD_2 PF13831.1 EEQ31066.1 - 3.2 7.1 10.3 8.7 5.7 1.1 3.5 3 0 0 3 3 3 0 PHD-finger Peptidase_M24 PF00557.19 EEQ31067.1 - 1.7e-13 50.6 0.0 2.1e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PBP1_TM PF14812.1 EEQ31067.1 - 5.4 7.4 10.4 13 6.1 7.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Exo_endo_phos PF03372.18 EEQ31068.1 - 4.1e-11 43.2 0.1 5.3e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.7 EEQ31069.1 - 3.1e-75 252.8 0.0 5.7e-75 251.9 0.0 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.1 EEQ31070.1 - 4.7e-08 33.1 7.5 1.2e-05 25.5 0.5 4.4 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EEQ31070.1 - 1.1e-06 28.2 2.5 0.06 13.4 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.3 EEQ31070.1 - 0.00015 21.2 0.0 0.15 11.4 0.0 2.7 1 1 1 2 2 2 2 CLASP N terminal HEAT_EZ PF13513.1 EEQ31070.1 - 0.0031 17.9 12.5 0.013 15.9 0.3 5.4 6 0 0 6 6 6 1 HEAT-like repeat DUF3734 PF12536.3 EEQ31070.1 - 0.26 11.4 4.2 1.3 9.1 0.0 3.9 4 0 0 4 4 4 0 Patatin phospholipase MFS_1 PF07690.11 EEQ31071.1 - 2.3e-39 135.0 39.7 2.3e-39 135.0 27.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PHD PF00628.24 EEQ31072.1 - 2.7e-10 39.7 5.0 2.7e-10 39.7 3.5 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EEQ31072.1 - 4e-09 36.1 1.7 4e-09 36.1 1.2 3.7 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EEQ31072.1 - 6.5e-07 29.3 0.7 6.5e-07 29.3 0.5 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EEQ31072.1 - 1.7e-06 27.6 0.5 1.7e-06 27.6 0.4 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ31072.1 - 3.1e-06 26.7 1.2 3.1e-06 26.7 0.8 3.1 2 2 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ31072.1 - 5.6e-06 26.2 1.2 5.6e-06 26.2 0.8 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ31072.1 - 1.3e-05 24.7 2.9 1.3e-05 24.7 2.0 2.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EEQ31072.1 - 1.7e-05 23.9 3.3 1.7e-05 23.9 2.3 1.7 2 0 0 2 2 1 1 PHD-finger zf-Apc11 PF12861.2 EEQ31072.1 - 0.00036 20.3 0.2 0.00036 20.3 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EEQ31072.1 - 0.018 14.5 5.9 0.029 13.8 0.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-PHD-like PF15446.1 EEQ31072.1 - 0.018 14.3 0.7 0.018 14.3 0.5 2.3 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain NMD3 PF04981.8 EEQ31072.1 - 0.098 11.7 0.8 0.19 10.8 0.5 1.5 1 0 0 1 1 1 0 NMD3 family zf-RING_4 PF14570.1 EEQ31072.1 - 0.14 11.7 6.1 0.039 13.5 0.6 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EEQ31072.1 - 0.28 11.0 7.0 1.5 8.7 1.9 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.1 EEQ31072.1 - 0.38 10.5 0.1 0.38 10.5 0.0 3.8 4 0 0 4 4 4 0 RING-type zinc-finger zf-RING-like PF08746.6 EEQ31072.1 - 1.8 8.6 10.9 3.7 7.6 1.4 2.5 2 0 0 2 2 2 0 RING-like domain FANCL_C PF11793.3 EEQ31072.1 - 6 6.9 7.8 0.66 9.9 0.1 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain Ribosomal_L37ae PF01780.14 EEQ31073.1 - 8.3e-40 134.5 11.0 9.2e-40 134.4 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EEQ31073.1 - 0.0009 19.0 2.4 0.0013 18.4 1.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 EEQ31073.1 - 0.012 15.3 3.0 0.52 10.1 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger NMDAR2_C PF10565.4 EEQ31073.1 - 0.14 10.8 0.7 0.15 10.7 0.5 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus A2L_zn_ribbon PF08792.5 EEQ31073.1 - 0.16 11.4 1.9 0.73 9.3 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Sec23_Sec24 PF04810.10 EEQ31073.1 - 0.22 11.1 1.8 2 8.0 0.1 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Elf1 PF05129.8 EEQ31073.1 - 0.26 11.0 2.5 0.46 10.2 1.7 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like NOB1_Zn_bind PF08772.6 EEQ31073.1 - 0.29 10.9 3.0 2.1 8.2 2.1 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Saccharop_dh PF03435.13 EEQ31074.1 - 5.7e-20 71.6 0.0 7.6e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EEQ31074.1 - 0.0056 16.9 0.0 0.015 15.6 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EEQ31074.1 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Abhydrolase_6 PF12697.2 EEQ31075.1 - 1.9e-24 86.8 0.0 2.9e-24 86.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ31075.1 - 1.8e-14 53.8 0.0 1.1e-13 51.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ31075.1 - 2.7e-12 46.6 0.0 1.2e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEQ31075.1 - 0.0015 18.3 0.1 0.0059 16.4 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Pinin_SDK_memA PF04696.8 EEQ31076.1 - 9.4e-27 93.1 6.0 9.4e-27 93.1 4.2 2.2 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region potato_inhibit PF00280.13 EEQ31076.1 - 0.13 12.4 0.3 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 Potato inhibitor I family Lipase_GDSL_3 PF14606.1 EEQ31076.1 - 4.5 6.9 6.8 0.28 10.9 0.7 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DIOX_N PF14226.1 EEQ31077.1 - 1e-27 96.9 0.0 1.6e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEQ31077.1 - 9.9e-10 38.6 0.0 1.9e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Myb_DNA-bind_6 PF13921.1 EEQ31078.1 - 7.3e-24 83.6 12.7 9e-14 51.3 0.4 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ31078.1 - 1.4e-19 69.8 13.2 2.8e-07 30.4 0.7 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EEQ31078.1 - 0.045 13.9 0.4 0.045 13.9 0.3 2.7 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 EEQ31078.1 - 0.38 10.6 11.5 4.9 7.1 0.9 3.7 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 EEQ31078.1 - 0.59 10.0 10.0 0.11 12.4 1.8 3.4 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain MFS_1 PF07690.11 EEQ31079.1 - 9.8e-38 129.7 47.5 1.8e-37 128.8 32.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ31079.1 - 3.4e-12 45.3 12.1 5.2e-12 44.7 8.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EEQ31080.1 - 3.3e-55 187.4 0.0 4.2e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 EEQ31081.1 - 4.7e-70 235.9 0.0 8.3e-70 235.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEQ31081.1 - 3.2e-30 104.4 0.0 6.7e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EEQ31081.1 - 1.2e-27 97.1 0.0 5e-27 95.0 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 EEQ31081.1 - 5.4e-23 81.2 0.0 8.6e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EEQ31081.1 - 4.9e-14 52.5 0.0 1.2e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ31081.1 - 3.6e-11 42.8 0.0 9.7e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ31081.1 - 7e-10 38.8 0.0 7e-09 35.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EEQ31081.1 - 1.7e-09 37.7 0.3 3.9e-09 36.6 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EEQ31081.1 - 8.9e-09 35.7 0.0 2.9e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EEQ31081.1 - 3.6e-07 29.8 0.0 1.4e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EEQ31081.1 - 2.1e-06 28.2 0.0 6.4e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EEQ31081.1 - 1.2e-05 24.4 0.1 1.2e-05 24.4 0.1 1.8 3 0 0 3 3 3 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 EEQ31081.1 - 1.3e-05 25.5 0.0 3.6e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ31081.1 - 2.2e-05 24.4 0.0 5.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EEQ31081.1 - 3.3e-05 23.8 0.1 6.5e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Ubie_methyltran PF01209.13 EEQ31081.1 - 5.9e-05 22.3 0.0 0.00014 21.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EEQ31081.1 - 7e-05 21.9 0.1 0.0002 20.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Polysacc_synt_2 PF02719.10 EEQ31081.1 - 0.003 16.5 0.0 0.017 14.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NodS PF05401.6 EEQ31081.1 - 0.0057 16.0 0.0 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) RmlD_sub_bind PF04321.12 EEQ31081.1 - 0.0066 15.3 0.0 2.8 6.7 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain DXP_reductoisom PF02670.11 EEQ31081.1 - 0.0078 16.7 0.3 0.029 14.9 0.0 2.1 2 0 0 2 2 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase KR PF08659.5 EEQ31081.1 - 0.015 14.9 0.2 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 KR domain Abhydrolase_5 PF12695.2 EEQ31081.1 - 0.024 14.3 0.0 0.92 9.2 0.0 2.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family PCMT PF01135.14 EEQ31081.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EEQ31081.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.14 EEQ31081.1 - 0.19 10.3 0.6 0.44 9.1 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1399 PF07173.7 EEQ31084.1 - 1.2e-23 83.8 0.4 9.1e-19 68.0 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Lipase_3 PF01764.20 EEQ31085.1 - 6.3e-18 64.7 0.0 9.9e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEQ31085.1 - 0.031 14.0 0.1 0.12 12.0 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.9 EEQ31085.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PHF5 PF03660.9 EEQ31086.1 - 2.8e-51 172.0 9.7 3.2e-51 171.8 6.7 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EEQ31086.1 - 0.55 10.0 15.1 0.09 12.6 5.1 2.7 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EEQ31086.1 - 2.8 7.7 16.6 6.9 6.4 0.5 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EEQ31086.1 - 3.5 5.1 5.3 3.6 5.1 3.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cofilin_ADF PF00241.15 EEQ31087.1 - 4e-19 68.7 0.0 8e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.22 EEQ31088.1 - 5.2e-68 224.8 1.5 2.5e-22 78.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CAF1 PF04857.15 EEQ31090.1 - 2.3e-40 138.5 0.0 2.7e-39 135.0 0.0 2.0 1 1 0 1 1 1 1 CAF1 family ribonuclease TFIIF_alpha PF05793.7 EEQ31091.1 - 0.0024 16.2 13.5 0.0036 15.7 9.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.8 EEQ31091.1 - 0.35 10.0 17.5 0.9 8.6 12.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 EEQ31091.1 - 0.46 8.1 9.1 0.6 7.7 6.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1682 PF07946.9 EEQ31091.1 - 0.48 9.2 14.9 0.94 8.2 10.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) OmpH PF03938.9 EEQ31091.1 - 0.78 9.6 14.8 1.6 8.6 10.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RtcB PF01139.12 EEQ31091.1 - 0.88 8.4 5.4 1.5 7.7 3.7 1.3 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB DUF1266 PF06889.6 EEQ31091.1 - 1.1 8.9 8.9 2.2 8.0 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) CCDC66 PF15236.1 EEQ31091.1 - 3.3 7.3 32.2 0.35 10.4 18.7 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 Ycf1 PF05758.7 EEQ31091.1 - 3.5 5.2 11.0 4.6 4.8 7.6 1.1 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 EEQ31091.1 - 4.2 5.5 15.2 5.9 5.0 10.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein APG6 PF04111.7 EEQ31091.1 - 4.8 6.1 18.3 8.7 5.2 12.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 MRP-L46 PF11788.3 EEQ31092.1 - 2.8e-35 121.3 0.3 4.5e-35 120.6 0.2 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Cript PF10235.4 EEQ31093.1 - 4.4e-33 113.4 8.8 4.4e-33 113.4 6.1 1.7 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 EEQ31093.1 - 0.0004 20.1 12.2 0.0097 15.7 5.9 2.9 2 1 1 3 3 3 2 Double zinc ribbon zf-ribbon_3 PF13248.1 EEQ31093.1 - 0.001 18.2 8.9 0.045 12.9 1.1 3.3 3 0 0 3 3 3 1 zinc-ribbon domain Yippee-Mis18 PF03226.9 EEQ31093.1 - 0.0081 16.1 2.4 0.083 12.9 0.0 2.2 1 1 1 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PolC_DP2 PF03833.8 EEQ31093.1 - 0.03 11.9 2.0 0.033 11.8 1.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-nanos PF05741.8 EEQ31093.1 - 0.23 11.4 6.9 0.15 12.0 2.5 2.1 2 0 0 2 2 2 0 Nanos RNA binding domain zf-C4pol PF14260.1 EEQ31093.1 - 0.58 10.1 11.9 1.8 8.6 5.5 2.5 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta FYVE PF01363.16 EEQ31093.1 - 1 9.3 13.5 1.7 8.5 5.6 2.4 1 1 1 2 2 2 0 FYVE zinc finger DUF1272 PF06906.6 EEQ31093.1 - 1.7 8.5 8.2 0.54 10.1 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF2039 PF10217.4 EEQ31093.1 - 9.4 6.3 19.3 3.4 7.7 8.4 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1349 PF07081.6 EEQ31094.1 - 5.9e-21 74.6 0.0 2.3e-09 36.8 0.0 3.3 3 1 0 3 3 3 2 Protein of unknown function (DUF1349) NOC3p PF07540.6 EEQ31097.1 - 8.5e-33 112.5 0.4 2.4e-32 111.0 0.3 1.8 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 EEQ31097.1 - 1.5e-31 109.1 0.1 4.1e-30 104.4 0.0 2.3 1 1 1 2 2 2 1 CBF/Mak21 family UPF0113 PF03657.8 EEQ31098.1 - 4.1e-07 29.8 0.0 6.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Cullin_binding PF03556.10 EEQ31099.1 - 2.8e-29 101.5 5.0 4.3e-29 101.0 3.5 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EEQ31099.1 - 2.1e-14 52.7 0.0 5.1e-14 51.5 0.0 1.7 2 0 0 2 2 2 1 UBA-like domain SprT-like PF10263.4 EEQ31100.1 - 4.7e-08 32.8 0.7 8e-08 32.0 0.5 1.3 1 0 0 1 1 1 1 SprT-like family Mpv17_PMP22 PF04117.7 EEQ31101.1 - 5.6e-13 48.3 1.2 5.8e-11 41.8 0.3 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family SSFA2_C PF14723.1 EEQ31102.1 - 0.11 12.1 3.4 0.16 11.6 2.4 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF1570 PF07607.6 EEQ31103.1 - 0.021 14.8 0.1 0.18 11.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1570) PEX11 PF05648.9 EEQ31104.1 - 1.1e-17 64.1 1.0 2.7e-15 56.2 0.7 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) AIG2 PF06094.7 EEQ31107.1 - 2.3e-07 31.2 0.0 5.2e-07 30.1 0.0 1.5 2 0 0 2 2 2 1 AIG2-like family AAA PF00004.24 EEQ31108.1 - 5.5e-97 321.0 0.0 1.1e-47 161.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EEQ31108.1 - 7.7e-20 70.6 1.0 2.1e-19 69.2 0.4 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EEQ31108.1 - 2.4e-14 53.6 0.0 9.1e-08 32.2 0.0 3.0 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EEQ31108.1 - 3.9e-13 49.0 0.0 1.7e-05 24.0 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEQ31108.1 - 5.7e-13 48.9 0.0 8.8e-06 25.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EEQ31108.1 - 3.8e-11 43.2 0.3 0.0035 17.4 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEQ31108.1 - 3.9e-11 43.8 0.0 0.00069 20.4 0.0 3.3 2 1 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EEQ31108.1 - 6.1e-11 42.2 0.8 1.3e-05 24.9 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEQ31108.1 - 3.5e-10 40.1 0.2 0.0006 19.8 0.0 3.8 3 2 0 3 3 2 2 AAA ATPase domain TIP49 PF06068.8 EEQ31108.1 - 6.7e-09 34.9 0.1 0.001 17.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EEQ31108.1 - 3.5e-08 33.0 5.7 0.019 14.3 0.0 4.8 3 2 2 5 5 4 2 AAA domain IstB_IS21 PF01695.12 EEQ31108.1 - 3.6e-08 33.0 0.0 0.0048 16.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EEQ31108.1 - 1.7e-07 30.8 1.6 0.0047 16.6 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 EEQ31108.1 - 1.8e-07 31.1 0.0 0.007 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EEQ31108.1 - 1.8e-07 30.6 0.0 4.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 EEQ31108.1 - 2.5e-07 30.0 0.0 0.0061 15.6 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin Mg_chelatase PF01078.16 EEQ31108.1 - 3.6e-07 29.5 0.4 0.028 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EEQ31108.1 - 1.2e-06 27.8 1.2 0.54 9.3 0.0 3.5 2 1 1 3 3 3 2 KaiC RNA_helicase PF00910.17 EEQ31108.1 - 1.5e-06 28.2 0.0 0.023 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EEQ31108.1 - 3.3e-06 27.4 0.0 0.066 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EEQ31108.1 - 3.4e-06 27.0 0.0 0.0047 16.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EEQ31108.1 - 8.7e-06 25.7 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EEQ31108.1 - 1.6e-05 23.9 0.0 0.0058 15.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EEQ31108.1 - 4.1e-05 23.9 0.0 0.22 11.8 0.0 3.3 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 EEQ31108.1 - 4.3e-05 22.8 0.4 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 EEQ31108.1 - 5.3e-05 22.9 0.4 0.14 11.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EEQ31108.1 - 5.9e-05 22.6 0.1 0.59 9.5 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EEQ31108.1 - 6.9e-05 22.9 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EEQ31108.1 - 8.8e-05 21.5 0.1 0.084 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EEQ31108.1 - 0.00013 21.7 0.1 5.8 6.5 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase Bac_DnaA PF00308.13 EEQ31108.1 - 0.00035 20.2 0.0 1.3 8.5 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein Vps4_C PF09336.5 EEQ31108.1 - 0.00053 19.8 0.2 0.0026 17.6 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EEQ31108.1 - 0.00054 19.5 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EEQ31108.1 - 0.00064 19.4 0.1 0.85 9.2 0.0 3.5 3 1 1 4 4 3 1 NACHT domain AAA_11 PF13086.1 EEQ31108.1 - 0.00064 19.3 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EEQ31108.1 - 0.0013 17.8 0.0 0.57 9.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EEQ31108.1 - 0.0014 18.2 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EEQ31108.1 - 0.0022 17.7 1.1 1 9.0 0.0 4.1 5 0 0 5 5 4 1 NTPase NB-ARC PF00931.17 EEQ31108.1 - 0.004 16.0 0.1 0.59 8.9 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 EEQ31108.1 - 0.0066 16.0 0.0 0.55 9.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EEQ31108.1 - 0.017 14.1 0.0 0.81 8.6 0.0 2.7 2 1 0 3 3 3 0 KAP family P-loop domain T2SE PF00437.15 EEQ31108.1 - 0.019 13.9 0.0 1.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.11 EEQ31108.1 - 0.024 13.8 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 EEQ31108.1 - 0.055 12.9 0.3 25 4.2 0.0 4.0 4 1 0 4 4 3 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 EEQ31108.1 - 0.059 12.8 1.1 10 5.4 0.0 3.6 3 1 0 4 4 4 0 AAA-like domain SKI PF01202.17 EEQ31108.1 - 0.089 12.6 0.0 9.1 6.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase eIF-1a PF01176.14 EEQ31108.1 - 0.12 11.8 0.5 1.4 8.4 0.1 2.6 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 KTI12 PF08433.5 EEQ31108.1 - 0.12 11.5 0.0 19 4.3 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EEQ31108.1 - 0.14 11.8 0.1 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 EnY2 PF10163.4 EEQ31109.1 - 0.00024 20.9 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.12 EEQ31110.1 - 2e-15 56.3 0.0 3.3e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EEQ31110.1 - 4.1e-15 56.0 0.0 8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EEQ31110.1 - 9.4e-12 44.9 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Nha1_C PF08619.5 EEQ31111.1 - 1.1e-70 239.1 19.7 1.4e-70 238.7 13.6 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EEQ31111.1 - 1.9e-63 214.3 17.3 2.2e-63 214.0 12.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EEQ31111.1 - 0.088 12.7 2.4 0.21 11.5 0.2 2.6 2 0 0 2 2 2 0 YrhC-like protein DUF21 PF01595.15 EEQ31111.1 - 0.32 10.2 3.2 1.1 8.5 2.2 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF21 PX PF00787.19 EEQ31112.1 - 7.7e-17 61.1 0.2 1.5e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.4 EEQ31112.1 - 0.038 12.5 0.9 0.072 11.6 0.6 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Blo-t-5 PF11642.3 EEQ31112.1 - 0.098 12.4 1.4 11 5.8 0.0 2.3 1 1 0 2 2 2 0 Mite allergen Blo t 5 AAA PF00004.24 EEQ31113.1 - 6.2e-08 32.9 0.1 6e-07 29.7 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EEQ31113.1 - 1.6e-05 23.7 0.3 0.00024 19.9 0.0 2.8 3 1 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EEQ31113.1 - 0.00025 21.8 0.0 0.00087 20.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EEQ31113.1 - 0.0026 17.9 0.0 0.0083 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ31113.1 - 0.0027 17.7 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EEQ31113.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EEQ31113.1 - 0.026 14.2 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EEQ31113.1 - 0.042 13.5 0.1 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 EEQ31113.1 - 0.064 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus DUF815 PF05673.8 EEQ31113.1 - 0.069 12.0 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EEQ31113.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 EEQ31115.1 - 1.3e-20 73.3 0.9 2.3e-20 72.5 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEQ31115.1 - 1.2e-09 37.9 14.8 4.6e-05 23.5 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ31115.1 - 5.5e-06 26.4 6.9 5.5e-06 26.4 4.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ31115.1 - 0.00054 20.1 15.1 0.1 12.9 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger WD40 PF00400.27 EEQ31118.1 - 2.8e-27 93.5 5.1 7.7e-10 38.2 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEQ31118.1 - 6e-19 67.7 0.0 1.3e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 EEQ31118.1 - 0.00034 19.4 0.1 0.41 9.3 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EEQ31118.1 - 0.0008 17.6 1.4 0.0018 16.5 0.1 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ras PF00071.17 EEQ31119.1 - 3e-27 95.0 0.1 5.3e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ31119.1 - 4.5e-20 72.3 0.0 1e-19 71.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ31119.1 - 1.6e-06 27.5 0.1 2.6e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ31119.1 - 0.00011 21.4 0.1 0.00021 20.5 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Bac_transf PF02397.11 EEQ31119.1 - 0.1 11.7 0.3 0.17 10.9 0.2 1.3 1 0 0 1 1 1 0 Bacterial sugar transferase BaxI_1 PF12811.2 EEQ31119.1 - 0.15 11.1 0.2 0.27 10.3 0.2 1.4 1 0 0 1 1 1 0 Bax inhibitor 1 like G-alpha PF00503.15 EEQ31119.1 - 0.93 8.1 13.0 0.17 10.5 0.1 2.5 1 1 0 2 2 2 0 G-protein alpha subunit DUF605 PF04652.11 EEQ31119.1 - 1.1 8.5 28.9 1.7 7.9 20.0 1.2 1 0 0 1 1 1 0 Vta1 like Transglut_core PF01841.14 EEQ31120.1 - 1e-11 45.0 0.0 1.9e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sugar_tr PF00083.19 EEQ31121.1 - 8.1e-86 288.3 24.0 1.6e-81 274.1 9.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ31121.1 - 3.4e-22 78.6 20.5 3.4e-22 78.6 14.2 2.6 1 1 1 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.1 EEQ31121.1 - 6.7e-07 28.0 1.0 6.7e-07 28.0 0.7 3.4 3 1 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 EEQ31121.1 - 3.7e-05 22.5 0.6 7.3e-05 21.6 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRI12 PF06609.8 EEQ31121.1 - 0.0031 15.7 1.4 0.0054 14.9 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TRAM_LAG1_CLN8 PF03798.11 EEQ31122.1 - 3.2e-36 124.7 19.4 5.3e-36 124.0 13.4 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EEQ31122.1 - 3.5e-22 77.6 0.1 1e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein vMSA PF00695.14 EEQ31123.1 - 3.1 6.9 7.4 3.8 6.6 5.1 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus MIP-T3 PF10243.4 EEQ31123.1 - 3.8 5.8 40.7 4.5 5.6 28.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MSP1_C PF07462.6 EEQ31123.1 - 5.5 5.2 10.1 7 4.9 7.0 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1510 PF07423.6 EEQ31123.1 - 5.6 6.2 22.0 7.8 5.8 15.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 EEQ31123.1 - 8.6 6.2 12.2 12 5.7 8.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family TIP120 PF08623.5 EEQ31124.1 - 8.7e-63 210.9 0.1 3.9e-61 205.5 0.0 3.3 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EEQ31124.1 - 1.2e-11 43.6 3.5 0.32 11.2 0.0 8.9 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 EEQ31124.1 - 7.3e-11 42.2 11.1 0.17 12.2 0.1 7.7 6 2 2 8 8 8 5 HEAT repeats Vac14_Fab1_bd PF12755.2 EEQ31124.1 - 0.00015 22.0 0.0 1.1 9.6 0.0 5.7 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EEQ31124.1 - 0.003 17.9 14.4 17 6.0 0.0 10.3 9 2 3 12 12 12 0 HEAT-like repeat Cnd1 PF12717.2 EEQ31124.1 - 0.017 14.9 0.1 0.32 10.8 0.0 3.4 3 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF3295 PF11702.3 EEQ31124.1 - 0.039 12.9 0.1 0.063 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DRIM PF07539.7 EEQ31124.1 - 0.045 13.1 0.0 0.57 9.5 0.0 2.8 2 0 0 2 2 2 0 Down-regulated in metastasis HEAT_PBS PF03130.11 EEQ31124.1 - 2.5 8.8 7.2 0.94 10.1 0.1 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat PalH PF08733.5 EEQ31127.1 - 2.4e-99 332.4 0.1 1.3e-98 330.0 0.0 1.8 1 1 0 1 1 1 1 PalH/RIM21 MFS_1 PF07690.11 EEQ31129.1 - 1.2e-38 132.7 45.9 4.2e-38 130.9 31.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ31129.1 - 1.6e-11 43.1 9.0 2.4e-11 42.5 6.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trep_Strep PF09605.5 EEQ31129.1 - 0.0016 18.1 0.7 0.0016 18.1 0.5 4.3 5 2 0 5 5 5 1 Hypothetical bacterial integral membrane protein (Trep_Strep) Atg14 PF10186.4 EEQ31132.1 - 5.3e-19 68.2 0.1 1e-18 67.3 0.1 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Mhr1 PF12829.2 EEQ31133.1 - 1.9e-29 101.3 0.0 5.2e-29 99.9 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Amidase PF01425.16 EEQ31133.1 - 0.21 10.4 0.8 0.3 9.8 0.6 1.2 1 0 0 1 1 1 0 Amidase PP2C PF00481.16 EEQ31134.1 - 7.4e-64 215.5 0.0 3.3e-50 170.8 0.0 3.4 2 1 0 2 2 2 2 Protein phosphatase 2C Snf7 PF03357.16 EEQ31135.1 - 5.3e-35 120.3 16.5 5.3e-35 120.3 11.5 2.4 3 0 0 3 3 3 1 Snf7 V_ATPase_I PF01496.14 EEQ31135.1 - 0.0041 15.0 6.1 0.0051 14.7 4.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Complex1_LYR_2 PF13233.1 EEQ31135.1 - 1.4 9.4 7.2 0.22 12.0 0.2 2.5 1 1 1 2 2 2 0 Complex1_LYR-like TPR_MLP1_2 PF07926.7 EEQ31135.1 - 7.1 6.3 12.5 21 4.8 8.6 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Dynamin_N PF00350.18 EEQ31136.1 - 8e-17 61.5 2.3 2e-16 60.2 0.0 2.8 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EEQ31136.1 - 9.6e-11 41.6 0.1 1.9e-08 34.2 0.0 3.8 2 2 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ31136.1 - 1.4e-06 27.9 0.2 2.1e-05 24.0 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.4 EEQ31136.1 - 0.0058 16.1 0.2 0.018 14.5 0.1 1.8 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Miro PF08477.8 EEQ31136.1 - 0.015 15.8 0.1 0.8 10.2 0.1 2.6 1 1 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 EEQ31136.1 - 0.017 14.3 0.6 16 4.7 0.0 4.0 5 0 0 5 5 5 0 Ferrous iron transport protein B AAA_29 PF13555.1 EEQ31136.1 - 0.038 13.5 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EEQ31136.1 - 0.11 12.8 0.9 0.36 11.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain PPV_E1_C PF00519.12 EEQ31136.1 - 0.15 10.6 0.0 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase TMF_TATA_bd PF12325.3 EEQ31136.1 - 0.8 9.4 5.9 0.21 11.3 1.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PTCB-BRCT PF12738.2 EEQ31137.1 - 1.9e-43 146.1 1.0 3.7e-22 77.9 0.1 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EEQ31137.1 - 4.5e-29 100.4 2.2 1.9e-12 47.1 0.1 4.4 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain PIF1 PF05970.9 EEQ31138.1 - 4.7e-61 206.7 0.1 7.1e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EEQ31138.1 - 6.8e-19 68.2 0.0 1.6e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ31138.1 - 9.8e-08 32.2 0.3 3.8e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 EEQ31138.1 - 1.5e-05 25.0 0.1 0.00025 21.1 0.1 2.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EEQ31138.1 - 1.9e-05 22.7 0.1 0.00021 19.2 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA PF00004.24 EEQ31138.1 - 4.6e-05 23.6 0.2 0.00013 22.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEQ31138.1 - 0.0011 18.7 0.2 0.0029 17.3 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EEQ31138.1 - 0.0014 18.1 0.0 0.4 10.1 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EEQ31138.1 - 0.0053 16.7 2.1 0.031 14.2 0.1 3.0 3 1 0 3 3 3 1 AAA ATPase domain DUF2075 PF09848.4 EEQ31138.1 - 0.014 14.4 1.5 0.029 13.3 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EEQ31138.1 - 0.017 14.3 0.0 0.047 12.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 EEQ31138.1 - 0.024 13.5 0.0 0.049 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EEQ31138.1 - 0.046 13.9 0.0 0.44 10.7 0.0 2.7 3 0 0 3 3 3 0 RNA helicase AAA_5 PF07728.9 EEQ31138.1 - 0.049 13.3 1.2 0.13 11.9 0.2 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EEQ31138.1 - 0.075 12.1 0.0 0.19 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 Arch_ATPase PF01637.13 EEQ31138.1 - 2.1 8.0 5.9 0.74 9.4 0.9 2.4 2 1 0 2 2 2 0 Archaeal ATPase SICA_C PF12879.2 EEQ31139.1 - 0.32 10.8 9.3 5.9 6.7 0.3 3.3 2 1 1 3 3 3 0 SICA C-terminal inner membrane domain Peptidase_S32 PF05579.8 EEQ31140.1 - 0.02 13.8 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Pro_isomerase PF00160.16 EEQ31141.1 - 2.4e-39 135.0 0.0 4.4e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EEQ31141.1 - 1.2e-06 27.9 0.5 4.2e-06 26.1 0.4 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 EEQ31141.1 - 0.00043 20.2 0.0 0.0018 18.2 0.0 2.0 1 1 0 1 1 1 1 U-box domain Polysacc_syn_2C PF08485.5 EEQ31141.1 - 0.1 12.1 0.3 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal Pkinase PF00069.20 EEQ31142.1 - 3.5e-18 65.7 0.1 1.1e-16 60.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31142.1 - 2.2e-09 36.7 0.7 1.8e-07 30.5 0.3 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ31142.1 - 7.8e-07 28.6 0.0 1.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family YjeF_N PF03853.10 EEQ31143.1 - 8.6e-32 110.0 0.1 1.5e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EEQ31143.1 - 1.6e-09 38.2 0.9 1.6e-09 38.2 0.7 2.2 1 1 1 2 2 2 1 FDF domain DUF3722 PF12519.3 EEQ31144.1 - 5.7e-87 291.2 2.9 7.4e-87 290.8 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) TIM PF00121.13 EEQ31145.1 - 9.7e-90 299.8 0.7 1.1e-89 299.7 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF3837 PF12939.2 EEQ31145.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) DUF924 PF06041.6 EEQ31146.1 - 2.8e-49 167.4 0.4 3.3e-49 167.2 0.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Methyltransf_2 PF00891.13 EEQ31147.1 - 2.4e-42 144.7 0.0 3e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEQ31147.1 - 4.7e-06 27.1 0.0 1.7e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ31147.1 - 0.0033 17.0 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ31147.1 - 0.052 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ31147.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EEQ31147.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AMP-binding PF00501.23 EEQ31148.1 - 3.7e-52 177.1 0.0 5.4e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EEQ31148.1 - 5.6e-26 92.1 0.2 1e-25 91.3 0.2 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EEQ31148.1 - 3e-12 46.6 0.2 7.3e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EEQ31148.1 - 3.6e-05 23.7 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ31148.1 - 0.00075 19.2 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EEQ31148.1 - 0.024 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Methyltransf_2 PF00891.13 EEQ31149.1 - 5.5e-28 97.7 0.0 8.6e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EEQ31149.1 - 0.0045 16.7 0.0 0.019 14.7 0.0 2.2 1 0 0 1 1 1 1 Dimerisation domain Cep57_MT_bd PF06657.8 EEQ31149.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 p450 PF00067.17 EEQ31150.1 - 2.4e-44 151.6 0.0 4.2e-36 124.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 SOG2 PF10428.4 EEQ31150.1 - 0.032 12.9 0.2 0.044 12.4 0.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.11 EEQ31152.1 - 3e-33 115.0 67.5 9.2e-32 110.1 28.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ31152.1 - 5.6e-11 41.6 10.0 5.6e-11 41.6 6.9 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter NmrA PF05368.8 EEQ31153.1 - 1.8e-32 112.4 0.0 4e-32 111.3 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ31153.1 - 1.7e-17 64.0 0.1 2.4e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEQ31153.1 - 0.0012 18.8 0.2 0.0033 17.3 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase p450 PF00067.17 EEQ31154.1 - 3.8e-23 81.7 0.0 1.1e-22 80.2 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L10 PF00466.15 EEQ31155.1 - 2.6e-17 62.5 0.0 4.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.3 EEQ31156.1 - 4.6e-33 113.4 0.6 9e-33 112.4 0.4 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EEQ31156.1 - 1.3e-16 59.9 0.0 2.7e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31156.1 - 1.1e-11 44.4 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ31156.1 - 2.6e-07 30.3 0.0 5.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 EEQ31157.1 - 2.4e-16 59.1 0.3 3.7e-16 58.5 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain FYVE PF01363.16 EEQ31158.1 - 0.0019 18.0 6.8 0.0033 17.2 4.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUF2296 PF10058.4 EEQ31158.1 - 0.0075 15.9 0.2 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) zf-RING_5 PF14634.1 EEQ31158.1 - 0.0084 15.8 5.7 0.017 14.8 4.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Zn_Tnp_IS1595 PF12760.2 EEQ31158.1 - 0.027 14.2 0.4 0.069 12.9 0.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-UBP PF02148.14 EEQ31158.1 - 0.037 14.1 6.3 0.1 12.7 4.3 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C3HC4_2 PF13923.1 EEQ31158.1 - 0.038 14.0 9.2 0.18 11.8 6.6 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 EEQ31158.1 - 0.038 13.6 2.3 0.09 12.4 1.6 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PhnA_Zn_Ribbon PF08274.7 EEQ31158.1 - 0.046 13.4 0.5 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon IBR PF01485.16 EEQ31158.1 - 0.13 12.1 8.5 0.093 12.6 3.3 2.2 1 1 1 2 2 2 0 IBR domain Ribosomal_L37ae PF01780.14 EEQ31158.1 - 0.15 11.9 0.9 1 9.2 0.5 2.1 2 0 0 2 2 2 0 Ribosomal L37ae protein family UPF0547 PF10571.4 EEQ31158.1 - 0.17 11.5 5.0 0.051 13.2 1.4 1.7 2 0 0 2 2 1 0 Uncharacterised protein family UPF0547 zf-B_box PF00643.19 EEQ31158.1 - 0.29 11.0 5.8 0.77 9.6 4.0 1.7 1 1 0 1 1 1 0 B-box zinc finger zf-RING_2 PF13639.1 EEQ31158.1 - 0.35 10.7 8.6 1.5 8.7 5.5 2.2 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 EEQ31158.1 - 0.61 9.7 6.7 8.7 6.0 5.4 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EEQ31158.1 - 1 9.1 7.7 0.88 9.3 2.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.1 EEQ31158.1 - 1.3 8.7 7.7 3.3 7.4 5.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prp19 PF08606.6 EEQ31159.1 - 4.8e-33 112.7 0.8 9.5e-33 111.7 0.5 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EEQ31159.1 - 4.3e-14 51.7 10.8 4.6e-07 29.4 0.0 6.6 8 0 0 8 8 8 4 WD domain, G-beta repeat eIF2A PF08662.6 EEQ31159.1 - 1.7e-07 31.1 0.1 0.0086 15.8 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EEQ31159.1 - 3.5e-07 29.3 0.4 0.0044 15.8 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 EEQ31159.1 - 0.0045 15.3 0.3 0.34 9.1 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain zf-Nse PF11789.3 EEQ31159.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Lactonase PF10282.4 EEQ31159.1 - 0.057 12.4 0.1 0.26 10.3 0.0 1.9 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF3312 PF11768.3 EEQ31159.1 - 0.058 11.6 0.0 0.1 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF4604 PF15377.1 EEQ31160.1 - 5.1e-28 98.2 13.0 6e-28 98.0 9.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) SPT6_acidic PF14632.1 EEQ31160.1 - 4.8 7.4 8.6 0.85 9.8 2.1 2.3 2 1 0 2 2 2 0 Acidic N-terminal SPT6 GTP_EFTU PF00009.22 EEQ31161.1 - 6.2e-53 179.0 0.0 1.1e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EEQ31161.1 - 3.1e-15 55.8 0.0 7.3e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EEQ31161.1 - 1.7e-07 30.9 0.0 3.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EEQ31161.1 - 1.9e-07 31.0 0.0 7.1e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EEQ31161.1 - 1e-05 25.0 0.0 0.001 18.5 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G, domain IV SET PF00856.23 EEQ31161.1 - 0.0023 18.2 0.1 0.039 14.2 0.0 2.3 2 0 0 2 2 2 1 SET domain MMR_HSR1 PF01926.18 EEQ31161.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EXOSC1 PF10447.4 EEQ31162.1 - 9.3e-28 96.0 2.9 9.3e-28 96.0 2.0 1.7 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EEQ31162.1 - 2.9e-14 52.0 0.1 4.6e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PixA PF12306.3 EEQ31162.1 - 0.025 14.4 0.5 0.74 9.6 0.0 2.3 1 1 0 2 2 2 0 Inclusion body protein Arm PF00514.18 EEQ31163.1 - 5.3e-65 213.2 27.6 3.3e-11 42.5 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEQ31163.1 - 5.6e-23 81.0 14.5 3.5e-07 30.4 0.4 7.7 2 1 4 7 7 7 6 HEAT repeats HEAT PF02985.17 EEQ31163.1 - 9.1e-19 65.8 13.8 0.032 14.3 0.0 9.7 10 0 0 10 10 10 5 HEAT repeat Adaptin_N PF01602.15 EEQ31163.1 - 1.9e-14 52.8 6.1 1.3e-08 33.6 0.1 2.8 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 EEQ31163.1 - 1.2e-13 51.0 19.3 0.0054 17.1 0.1 8.5 8 3 3 11 11 11 5 HEAT-like repeat KAP PF05804.7 EEQ31163.1 - 3.6e-09 35.1 0.4 1.3e-08 33.2 0.1 1.8 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EEQ31163.1 - 3.5e-08 32.9 0.6 0.0013 17.8 0.3 3.0 2 1 1 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.8 EEQ31163.1 - 4.5e-08 32.5 6.7 0.00025 20.2 2.7 3.1 1 1 0 2 2 2 2 Armadillo-like HEAT_PBS PF03130.11 EEQ31163.1 - 0.00069 19.8 7.9 1 10.0 0.4 6.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ31163.1 - 0.013 15.8 0.1 0.42 11.0 0.0 3.1 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Pkinase PF00069.20 EEQ31164.1 - 6.3e-25 87.7 0.0 2.8e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31164.1 - 6.5e-07 28.6 0.0 0.00019 20.5 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase FHA PF00498.21 EEQ31165.1 - 1.7e-14 53.6 0.0 3.9e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EEQ31165.1 - 1.2e-05 24.9 9.5 2.4e-05 24.0 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ31165.1 - 0.013 15.1 6.5 0.026 14.2 4.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 EEQ31165.1 - 0.014 15.5 6.0 0.034 14.2 4.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEQ31165.1 - 0.021 14.4 7.7 0.041 13.5 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ31165.1 - 0.052 13.3 2.5 0.13 12.1 1.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-H2C2_2 PF13465.1 EEQ31165.1 - 0.15 12.4 2.0 0.34 11.2 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C3HC4_2 PF13923.1 EEQ31165.1 - 0.2 11.7 9.7 0.38 10.8 6.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EEQ31165.1 - 0.22 11.2 5.9 0.44 10.2 4.1 1.6 1 0 0 1 1 1 0 PHD-finger DUF605 PF04652.11 EEQ31165.1 - 0.47 9.7 55.2 0.02 14.3 21.0 2.4 2 0 0 2 2 2 0 Vta1 like zf-RING-like PF08746.6 EEQ31165.1 - 2.4 8.2 9.2 5.8 6.9 6.4 1.7 1 0 0 1 1 1 0 RING-like domain Bestrophin PF01062.16 EEQ31166.1 - 6.5e-45 153.3 0.0 2.7e-44 151.2 0.0 1.7 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel AAA_22 PF13401.1 EEQ31168.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Lipase_GDSL_2 PF13472.1 EEQ31169.1 - 3.4e-11 43.5 0.1 1.9e-09 37.9 0.0 2.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ31169.1 - 5.2e-07 29.7 0.6 3e-05 23.9 0.4 3.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_18 PF00704.23 EEQ31171.1 - 4.4e-74 249.9 0.2 5.4e-74 249.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EEQ31171.1 - 7.2e-08 32.2 9.5 7.2e-08 32.2 6.6 2.7 2 1 0 2 2 2 2 Chitin recognition protein LysM PF01476.15 EEQ31172.1 - 8.7e-31 105.5 2.7 5.6e-08 32.5 0.0 6.3 6 0 0 6 6 6 6 LysM domain Vps16_N PF04841.8 EEQ31174.1 - 2.1e-97 326.2 0.0 5.2e-97 324.9 0.0 1.6 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.7 EEQ31174.1 - 6.5e-84 281.5 0.1 1.2e-83 280.7 0.0 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region Alb1 PF09135.6 EEQ31175.1 - 5.3e-27 94.6 10.1 7.7e-27 94.1 7.0 1.3 1 0 0 1 1 1 1 Alb1 UCH PF00443.24 EEQ31176.1 - 4.1e-31 108.0 0.0 6.6e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ31176.1 - 2.5e-12 46.8 0.0 4.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_9 PF14658.1 EEQ31177.1 - 0.00068 19.5 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.1 EEQ31177.1 - 0.013 15.3 0.1 1.2 9.1 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 EEQ31177.1 - 0.034 13.4 0.0 9.9 5.7 0.0 3.3 3 0 0 3 3 3 0 EF hand T2SG PF08334.6 EEQ31177.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein G Peptidase_C97 PF05903.9 EEQ31178.1 - 2.4e-39 134.5 0.0 3.3e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EEQ31178.1 - 3.8e-16 58.6 0.0 5.7e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF2847 PF11009.3 EEQ31178.1 - 2.9e-05 23.6 0.0 6.5e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2847) Thioredoxin_2 PF13098.1 EEQ31178.1 - 6.8e-05 23.0 0.1 0.00045 20.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 EEQ31178.1 - 0.0032 17.0 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 EEQ31178.1 - 0.0076 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain Redoxin PF08534.5 EEQ31178.1 - 0.012 15.1 0.1 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 Redoxin AhpC-TSA PF00578.16 EEQ31178.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family T4_deiodinase PF00837.12 EEQ31178.1 - 0.019 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase Thioredoxin_4 PF13462.1 EEQ31178.1 - 0.031 14.2 0.5 0.093 12.7 0.1 1.7 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_8 PF13905.1 EEQ31178.1 - 0.059 13.4 0.0 0.28 11.3 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like IBR PF01485.16 EEQ31179.1 - 7.1e-07 29.0 9.5 7.1e-07 29.0 6.6 2.3 3 0 0 3 3 3 1 IBR domain Cluap1 PF10234.4 EEQ31179.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 AMP-binding PF00501.23 EEQ31180.1 - 1.1e-71 241.4 0.3 2.1e-71 240.5 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme HxxPF_rpt PF13745.1 EEQ31180.1 - 3.5e-21 75.3 1.3 5.6e-21 74.6 0.2 2.0 2 0 0 2 2 2 1 HxxPF-repeated domain Thioesterase PF00975.15 EEQ31180.1 - 5.1e-17 62.8 0.0 1.6e-16 61.2 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain Condensation PF00668.15 EEQ31180.1 - 1.8e-16 59.8 0.0 3e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Abhydrolase_6 PF12697.2 EEQ31180.1 - 1.4e-10 41.4 0.1 4.1e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding_C PF13193.1 EEQ31180.1 - 2e-09 38.2 0.1 6.5e-09 36.6 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EEQ31180.1 - 4e-09 36.5 0.0 9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EEQ31180.1 - 1.9e-07 30.9 0.0 4.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEQ31180.1 - 0.00032 20.3 0.0 0.00074 19.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PTR2 PF00854.16 EEQ31181.1 - 3.3e-44 151.1 12.1 1.8e-22 79.6 0.1 3.0 1 1 0 2 2 2 2 POT family MFS_1 PF07690.11 EEQ31183.1 - 4.3e-28 98.0 31.5 1.4e-15 56.8 6.2 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ31183.1 - 1.1e-09 37.3 8.4 1.1e-09 37.3 5.8 3.0 1 1 0 2 2 2 1 Sugar (and other) transporter SNF2_N PF00176.18 EEQ31186.1 - 1.2e-29 103.0 0.1 6.9e-29 100.5 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 EEQ31186.1 - 9.4e-12 45.1 0.0 1.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ31186.1 - 4.2e-07 29.7 0.0 1.1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PIF1 PF05970.9 EEQ31187.1 - 7.6e-29 100.7 0.0 4.3e-25 88.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 EEQ31187.1 - 9.9e-25 87.3 0.6 1.9e-24 86.3 0.4 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EEQ31187.1 - 2.9e-08 33.5 0.0 2.2e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ31187.1 - 0.00048 19.8 0.0 0.002 17.8 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain Herpes_Helicase PF02689.9 EEQ31187.1 - 0.00055 17.8 0.0 0.001 16.9 0.0 1.3 1 0 0 1 1 1 1 Helicase KAP_NTPase PF07693.9 EEQ31187.1 - 0.00088 18.3 0.0 0.0025 16.8 0.0 1.7 2 0 0 2 2 2 1 KAP family P-loop domain UvrD_C_2 PF13538.1 EEQ31187.1 - 0.0032 17.5 0.0 0.0085 16.2 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Torsin PF06309.6 EEQ31187.1 - 0.018 14.9 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Torsin Fungal_trans PF04082.13 EEQ31188.1 - 4.1e-07 29.1 1.8 6.6e-07 28.4 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain NAAA-beta PF15508.1 EEQ31189.1 - 0.033 14.5 0.1 0.081 13.2 0.0 1.7 1 1 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HET PF06985.6 EEQ31190.1 - 7.8e-18 64.9 2.8 2.5e-14 53.6 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 EEQ31190.1 - 0.00059 19.3 14.0 0.00093 18.6 5.6 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type PADR1 PF08063.7 EEQ31190.1 - 0.89 9.0 7.8 0.46 9.9 2.6 2.3 2 0 0 2 2 2 0 PADR1 (NUC008) domain Phosphoesterase PF04185.9 EEQ31191.1 - 8.3e-62 209.5 0.2 3.5e-61 207.4 0.2 1.9 1 1 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.10 EEQ31192.1 - 3.2e-17 62.3 0.0 1.4e-15 57.0 0.0 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EEQ31192.1 - 2.5e-13 50.2 0.0 1.2e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase WW PF00397.21 EEQ31193.1 - 0.00021 21.0 0.7 0.00047 19.9 0.5 1.6 1 0 0 1 1 1 1 WW domain Methyltransf_23 PF13489.1 EEQ31194.1 - 1.1e-05 25.2 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ31194.1 - 0.00072 19.9 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ31194.1 - 0.004 16.7 0.0 0.042 13.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ31194.1 - 0.0068 16.7 0.0 0.02 15.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ31194.1 - 0.02 15.3 0.0 0.082 13.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EEQ31194.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.9 EEQ31194.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Opy2 PF09463.5 EEQ31195.1 - 5.4e-06 26.3 19.5 5.4e-06 26.3 13.5 2.0 2 0 0 2 2 2 1 Opy2 protein Herpes_gE PF02480.11 EEQ31195.1 - 0.0078 14.5 0.6 0.017 13.4 0.0 1.8 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EEQ31195.1 - 0.069 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AMP-binding PF00501.23 EEQ31196.1 - 3.5e-46 157.4 0.0 5.2e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ31196.1 - 0.02 15.8 0.0 0.047 14.6 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Chitin_synth_1 PF01644.12 EEQ31197.1 - 1.3e-68 229.9 0.0 1.9e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EEQ31197.1 - 6.5e-28 96.2 0.0 1.2e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEQ31197.1 - 7.6e-25 87.2 0.0 1.5e-19 69.8 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EEQ31197.1 - 3.6e-12 46.4 0.2 3.6e-12 46.4 0.1 2.6 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ31197.1 - 9.1e-08 32.1 0.0 3.5e-07 30.2 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 UQ_con PF00179.21 EEQ31198.1 - 5.8e-35 119.7 0.0 7.4e-35 119.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ31198.1 - 0.041 13.6 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B TAF8_C PF10406.4 EEQ31199.1 - 8.9e-19 67.2 0.9 2e-18 66.1 0.6 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EEQ31199.1 - 7.8e-07 28.7 0.0 1.9e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated Mitochondr_Som1 PF11093.3 EEQ31200.1 - 1.1e-07 31.5 0.0 1.1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Rad51 PF08423.6 EEQ31201.1 - 0.0076 15.1 0.1 0.035 13.0 0.0 1.9 2 0 0 2 2 2 1 Rad51 DUF2317 PF10079.4 EEQ31201.1 - 0.18 10.3 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) PALP PF00291.20 EEQ31202.1 - 1.1e-70 238.3 0.0 1.3e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEQ31202.1 - 0.0017 17.5 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family IlvN PF07991.7 EEQ31203.1 - 9e-46 155.2 0.0 1.4e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EEQ31203.1 - 2.5e-45 153.9 0.0 4.2e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EEQ31203.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEQ31203.1 - 0.11 12.9 0.2 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2OG-FeII_Oxy_2 PF13532.1 EEQ31204.1 - 1.7e-24 86.7 0.0 3.2e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EEQ31204.1 - 6.1e-21 75.1 0.0 1.4e-14 54.4 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family 2OG-FeII_Oxy PF03171.15 EEQ31204.1 - 0.0044 17.2 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_N_3 PF13417.1 EEQ31204.1 - 0.04 14.1 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ31204.1 - 0.047 13.7 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain ECH PF00378.15 EEQ31205.1 - 7.9e-40 136.5 0.0 1.1e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Tbf5 PF06331.7 EEQ31206.1 - 8.9e-21 73.4 0.1 9.8e-21 73.3 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Trypsin_2 PF13365.1 EEQ31207.1 - 4.6e-05 23.4 0.0 9.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.4 EEQ31207.1 - 0.023 13.1 0.0 0.036 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S32 PF05579.8 EEQ31207.1 - 0.045 12.7 0.0 0.085 11.8 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S7 PF00949.16 EEQ31207.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease FAD_binding_4 PF01565.18 EEQ31208.1 - 1.3e-24 86.2 6.1 2.1e-24 85.5 4.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ31208.1 - 2e-07 30.8 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EEQ31209.1 - 0.00063 18.3 0.0 0.00083 17.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.7 EEQ31210.1 - 3.9e-09 36.8 0.0 6.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ31210.1 - 1.6e-08 34.8 0.0 3.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ31210.1 - 1.7e-08 34.8 0.0 2.2e-07 31.2 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ31210.1 - 4.3e-08 33.7 0.0 1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ31210.1 - 1e-06 28.3 0.0 2.1e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ31210.1 - 6.4e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ31210.1 - 0.0029 17.3 0.0 0.0048 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ31210.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EEQ31210.1 - 0.0078 15.2 0.0 0.02 13.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 EEQ31210.1 - 0.029 13.2 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase APH PF01636.18 EEQ31211.1 - 9.1e-13 48.4 0.0 1.7e-12 47.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ31211.1 - 4e-05 23.3 0.0 5.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ31211.1 - 0.014 14.7 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EEQ31211.1 - 0.086 11.9 0.0 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Gmx_para_CXXCG PF09535.5 EEQ31211.1 - 0.1 11.5 0.0 0.19 10.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) GTP_EFTU PF00009.22 EEQ31212.1 - 2e-49 167.5 0.0 3.3e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EEQ31212.1 - 1.9e-35 121.0 3.0 3.3e-35 120.2 2.1 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EEQ31212.1 - 1.5e-19 69.6 0.0 2.7e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 EEQ31212.1 - 1.4e-05 24.4 0.0 8.9e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EEQ31212.1 - 4.2e-05 23.4 0.1 0.00014 21.7 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EEQ31212.1 - 0.00015 21.8 0.5 0.00033 20.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EEQ31212.1 - 0.00074 19.3 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EEQ31212.1 - 0.012 14.8 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit HORMA PF02301.13 EEQ31213.1 - 1.8e-35 122.3 0.7 7.3e-34 117.0 0.5 2.0 1 1 0 1 1 1 1 HORMA domain PAT1 PF09770.4 EEQ31214.1 - 0.00036 18.9 27.6 0.00036 18.9 19.2 4.1 3 1 1 4 4 4 1 Topoisomerase II-associated protein PAT1 Sec1 PF00995.18 EEQ31215.1 - 1.6e-153 512.3 0.0 1.9e-153 512.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FHA PF00498.21 EEQ31217.1 - 6e-12 45.5 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain TPR_11 PF13414.1 EEQ31218.1 - 5e-47 157.4 28.9 7.1e-14 51.2 0.6 6.8 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 EEQ31218.1 - 4.5e-37 124.1 33.3 4.4e-06 26.0 0.1 10.7 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ31218.1 - 2.2e-35 117.7 32.3 5.4e-05 22.8 0.1 11.2 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ31218.1 - 2.2e-24 85.1 27.2 3.7e-07 29.9 0.0 6.7 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ31218.1 - 6.3e-23 80.8 24.8 2e-05 25.1 0.5 6.8 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ31218.1 - 2.4e-15 55.3 17.0 0.31 11.3 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ31218.1 - 6.4e-15 53.6 15.6 0.0097 15.6 0.5 9.1 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ31218.1 - 1.1e-13 49.9 26.6 0.011 15.4 0.0 10.1 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ31218.1 - 2e-11 43.6 14.0 0.018 14.8 1.3 6.5 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ31218.1 - 2.2e-11 43.9 20.6 2.2e-06 27.8 1.3 6.7 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ31218.1 - 3.2e-11 42.8 21.3 0.018 15.6 0.8 9.8 4 4 6 10 10 10 3 Tetratricopeptide repeat Apc3 PF12895.2 EEQ31218.1 - 4.8e-10 39.4 19.7 0.0045 17.1 0.8 5.3 3 1 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EEQ31218.1 - 8.6e-05 22.3 12.4 0.17 11.8 0.5 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF1510 PF07423.6 EEQ31218.1 - 0.0016 17.8 2.4 0.003 16.9 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF3856 PF12968.2 EEQ31218.1 - 0.0044 16.8 5.8 3.6 7.4 0.0 4.9 3 1 2 5 5 5 1 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.4 EEQ31218.1 - 0.074 12.3 16.8 0.89 8.8 0.0 6.9 8 0 0 8 8 8 0 SHNi-TPR TPR_6 PF13174.1 EEQ31218.1 - 0.12 12.8 24.8 4 8.1 0.6 8.5 10 0 0 10 10 8 0 Tetratricopeptide repeat Sel1 PF08238.7 EEQ31218.1 - 0.42 11.3 8.5 0.75 10.5 0.2 4.2 4 0 0 4 4 3 0 Sel1 repeat TPR_3 PF07720.7 EEQ31218.1 - 4.7 7.1 14.9 8.2 6.3 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Aminotran_4 PF01063.14 EEQ31219.1 - 2.3e-32 112.3 0.0 2.7e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV YpjP PF14005.1 EEQ31219.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 YpjP-like protein Nramp PF01566.13 EEQ31220.1 - 4.8e-89 298.6 22.4 7.8e-89 297.9 15.5 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein CAML PF14963.1 EEQ31220.1 - 0.2 11.0 0.2 0.53 9.6 0.1 1.7 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Peptidase_S8 PF00082.17 EEQ31221.1 - 1.1e-44 152.6 15.5 2e-44 151.8 10.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ31221.1 - 2.2e-14 53.7 0.4 3.9e-14 52.9 0.3 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Hydrolase_3 PF08282.7 EEQ31221.1 - 0.063 12.8 0.2 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.19 EEQ31223.1 - 2.6e-82 276.8 23.1 3.2e-82 276.5 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ31223.1 - 1.7e-15 56.6 31.8 5.2e-15 55.0 16.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.18 EEQ31224.1 - 6.7e-99 330.7 1.2 6.7e-99 330.7 0.8 2.5 3 0 0 3 3 3 1 Kinesin motor domain DUF1900 PF08954.6 EEQ31225.1 - 1.2e-50 170.5 0.0 1e-49 167.5 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EEQ31225.1 - 7.5e-33 111.9 0.0 1.5e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EEQ31225.1 - 1.8e-20 71.9 0.7 3.1e-06 26.8 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EEQ31225.1 - 0.048 11.8 0.2 0.095 10.8 0.1 1.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 zf-C3HC4_3 PF13920.1 EEQ31226.1 - 0.0027 17.3 9.5 0.0047 16.5 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EEQ31226.1 - 0.57 10.0 5.8 1 9.2 4.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EEQ31226.1 - 3.9 7.2 10.8 6.3 6.6 7.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ31226.1 - 9.1 6.4 12.1 14 5.7 8.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CBFD_NFYB_HMF PF00808.18 EEQ31228.1 - 3.8e-14 52.4 1.0 5.9e-14 51.8 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ31228.1 - 3.4e-06 27.0 0.2 5.4e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TSKS PF15358.1 EEQ31228.1 - 0.056 11.5 6.1 0.078 11.1 4.2 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate PAT1 PF09770.4 EEQ31228.1 - 0.1 10.8 42.7 0.12 10.5 29.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OmpH PF03938.9 EEQ31228.1 - 0.16 11.8 20.1 0.26 11.2 14.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med15 PF09606.5 EEQ31228.1 - 2.5 6.2 49.8 4 5.5 34.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BTB PF00651.26 EEQ31229.1 - 0.00028 20.8 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RAI16-like PF10257.4 EEQ31230.1 - 7.1e-75 252.1 0.0 1.2e-74 251.3 0.0 1.4 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein Lipase_3 PF01764.20 EEQ31231.1 - 4.6e-18 65.1 0.0 1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEQ31231.1 - 0.026 14.2 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zip PF02535.17 EEQ31231.1 - 0.17 10.8 5.3 0.29 10.0 3.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Inhibitor_I9 PF05922.11 EEQ31231.1 - 2 9.0 6.7 5.1 7.7 2.5 2.4 2 0 0 2 2 2 0 Peptidase inhibitor I9 ILVD_EDD PF00920.16 EEQ31232.1 - 5.4e-203 675.1 0.2 6.3e-203 674.9 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family APH PF01636.18 EEQ31236.1 - 1.3e-13 51.2 0.0 6.5e-13 48.9 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ31237.1 - 6.5e-49 166.4 0.0 8.5e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31237.1 - 1e-28 100.1 0.0 1.4e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ31237.1 - 0.0014 17.6 0.0 0.0084 15.1 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Tim17 PF02466.14 EEQ31239.1 - 6.8e-28 97.2 3.5 8.2e-28 97.0 2.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NPBW PF15180.1 EEQ31239.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.5 1 1 0 1 1 1 0 Neuropeptides B and W DUF2428 PF10350.4 EEQ31240.1 - 7.6e-65 218.4 0.5 1.5e-64 217.5 0.3 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_EZ PF13513.1 EEQ31240.1 - 0.012 16.1 0.4 0.44 11.1 0.1 3.7 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.17 EEQ31240.1 - 0.012 15.6 2.5 1.7 8.9 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat Ctr PF04145.10 EEQ31241.1 - 0.02 14.9 2.2 0.08 12.9 1.5 2.0 1 1 0 1 1 1 0 Ctr copper transporter family DUF1191 PF06697.7 EEQ31241.1 - 0.16 10.7 0.0 0.16 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) FixQ PF05545.6 EEQ31241.1 - 0.27 10.8 0.2 0.27 10.8 0.1 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PX PF00787.19 EEQ31242.1 - 3.7e-19 68.5 0.0 1.2e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EEQ31242.1 - 3.6e-11 42.7 5.4 2.1e-05 23.9 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like UCH PF00443.24 EEQ31243.1 - 1.5e-73 247.1 0.0 4.4e-73 245.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ31243.1 - 3.4e-15 56.2 0.0 1.3e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EEQ31243.1 - 4.7e-14 52.5 0.0 1.3e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 EEQ31243.1 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal ubiquitin PF00240.18 EEQ31243.1 - 0.044 13.1 0.1 0.1 11.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin family USP7_ICP0_bdg PF12436.3 EEQ31243.1 - 0.098 11.8 0.1 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 zf-FPG_IleRS PF06827.9 EEQ31243.1 - 2.3 7.9 4.6 14 5.4 0.1 3.0 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS ABC_tran PF00005.22 EEQ31245.1 - 3.1e-47 160.3 0.1 3.6e-23 82.3 0.0 3.8 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ31245.1 - 1e-16 60.8 0.1 1.1e-06 28.0 0.0 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ31245.1 - 4.5e-16 59.6 2.4 0.0016 18.4 0.1 4.3 3 1 0 4 4 4 3 AAA domain AAA_29 PF13555.1 EEQ31245.1 - 4e-10 39.0 0.0 0.0011 18.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EEQ31245.1 - 2.7e-09 37.6 2.1 0.00031 21.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EEQ31245.1 - 4.4e-08 32.4 0.1 0.00013 21.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ31245.1 - 1.7e-07 32.0 0.0 0.0023 18.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EEQ31245.1 - 7.9e-07 29.1 0.0 0.011 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EEQ31245.1 - 1.3e-06 28.5 0.2 0.14 12.3 0.0 5.1 6 0 0 6 6 4 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EEQ31245.1 - 1.7e-06 28.0 0.0 0.017 15.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EEQ31245.1 - 2.6e-06 27.5 0.0 0.037 14.1 0.0 3.5 4 0 0 4 4 2 2 AAA domain SbcCD_C PF13558.1 EEQ31245.1 - 2.8e-06 27.1 0.0 0.037 13.9 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EEQ31245.1 - 7.2e-06 25.6 0.1 0.21 11.0 0.0 3.3 4 1 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 EEQ31245.1 - 1e-05 25.4 0.0 0.21 11.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EEQ31245.1 - 1.1e-05 25.9 0.0 0.023 15.1 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EEQ31245.1 - 1.4e-05 25.1 2.6 0.44 10.5 0.0 4.4 4 1 0 4 4 4 2 AAA ATPase domain AAA_15 PF13175.1 EEQ31245.1 - 1.9e-05 23.8 2.1 0.5 9.3 0.0 4.0 3 2 2 5 5 5 2 AAA ATPase domain AAA_18 PF13238.1 EEQ31245.1 - 2.2e-05 24.7 0.2 0.34 11.2 0.0 3.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEQ31245.1 - 2.4e-05 24.0 0.0 0.03 13.9 0.0 2.9 2 1 0 2 2 2 1 NACHT domain ArgK PF03308.11 EEQ31245.1 - 2.9e-05 22.9 1.3 0.09 11.5 0.0 2.8 3 0 0 3 3 3 2 ArgK protein PduV-EutP PF10662.4 EEQ31245.1 - 4.8e-05 22.8 0.0 0.13 11.7 0.0 3.0 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EEQ31245.1 - 5.5e-05 23.0 0.3 0.23 11.2 0.0 3.2 3 0 0 3 3 2 2 Domain of unknown function DUF87 Dynamin_N PF00350.18 EEQ31245.1 - 7.1e-05 22.6 0.0 0.0083 15.9 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_13 PF13166.1 EEQ31245.1 - 0.00011 20.7 0.6 1.4 7.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.17 EEQ31245.1 - 0.00014 22.0 0.0 0.62 10.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EEQ31245.1 - 0.00033 20.3 0.0 0.99 9.1 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EEQ31245.1 - 0.00045 20.1 0.0 2.3 8.1 0.0 3.5 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EEQ31245.1 - 0.00066 19.4 0.0 0.56 9.8 0.0 3.1 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EEQ31245.1 - 0.0018 17.7 0.1 1.7 8.0 0.0 3.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EEQ31245.1 - 0.002 17.5 0.0 3 7.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EEQ31245.1 - 0.0027 17.2 0.0 2.9 7.3 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_PrkA PF08298.6 EEQ31245.1 - 0.0097 14.6 0.0 15 4.1 0.0 3.1 3 0 0 3 3 3 0 PrkA AAA domain ATP_bind_1 PF03029.12 EEQ31245.1 - 0.011 15.2 0.0 4.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3385 PF11865.3 EEQ31245.1 - 0.013 15.4 0.2 0.11 12.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) FtsK_SpoIIIE PF01580.13 EEQ31245.1 - 0.014 14.8 0.1 2.5 7.5 0.0 3.3 3 1 0 3 3 3 0 FtsK/SpoIIIE family MutS_V PF00488.16 EEQ31245.1 - 0.019 14.3 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 MutS domain V HEAT_2 PF13646.1 EEQ31245.1 - 0.023 14.9 7.5 1.3 9.3 0.0 3.4 1 1 2 3 3 3 0 HEAT repeats AAA_5 PF07728.9 EEQ31245.1 - 0.023 14.3 0.0 14 5.4 0.0 3.5 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EEQ31245.1 - 0.027 13.6 0.5 2.3 7.3 0.0 3.2 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI Septin PF00735.13 EEQ31245.1 - 0.031 13.2 0.4 1.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Septin AAA_19 PF13245.1 EEQ31245.1 - 0.034 13.9 0.1 5.8 6.7 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 EEQ31245.1 - 0.05 12.4 0.1 0.55 9.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain HEAT PF02985.17 EEQ31245.1 - 1 9.6 3.8 27 5.2 0.0 4.1 4 0 0 4 4 2 0 HEAT repeat HEAT_EZ PF13513.1 EEQ31245.1 - 2.6 8.6 9.8 21 5.7 0.0 5.2 4 2 3 7 7 6 0 HEAT-like repeat Mu-like_Pro PF10123.4 EEQ31245.1 - 7.7 5.8 15.0 2.5 7.4 8.0 1.9 2 0 0 2 2 1 0 Mu-like prophage I protein TPR_11 PF13414.1 EEQ31246.1 - 3.1e-11 42.7 0.1 3.9e-07 29.6 0.0 4.3 4 1 2 6 6 6 3 TPR repeat TPR_17 PF13431.1 EEQ31246.1 - 0.0003 20.7 0.2 0.88 9.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ31246.1 - 0.00089 18.7 7.9 0.026 14.1 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ31246.1 - 0.0024 17.7 6.1 2.7 7.9 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ31246.1 - 0.0053 16.4 6.4 0.33 10.8 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ31246.1 - 0.034 14.7 18.1 0.12 13.0 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ31246.1 - 0.045 13.6 0.0 0.045 13.6 0.0 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ31246.1 - 0.43 10.4 8.1 3.7 7.4 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ31246.1 - 0.66 10.7 0.0 0.66 10.7 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Oxidored_q6 PF01058.17 EEQ31247.1 - 2.4e-23 82.1 0.0 3.1e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF1275 PF06912.6 EEQ31248.1 - 3.5e-22 78.6 9.1 3.5e-22 78.6 6.3 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1275) Rick_17kDa_Anti PF05433.10 EEQ31249.1 - 0.02 14.5 25.7 0.045 13.4 17.8 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain SR-25 PF10500.4 EEQ31249.1 - 0.082 12.3 12.2 0.13 11.6 8.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gly-zipper_Omp PF13488.1 EEQ31249.1 - 0.34 10.5 22.5 1 9.0 15.6 1.9 1 0 0 1 1 1 0 Glycine zipper TraT PF05818.7 EEQ31249.1 - 4.1 6.7 9.0 0.035 13.5 1.0 1.4 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein BLVR PF06375.6 EEQ31249.1 - 5.3 6.8 17.8 0.34 10.7 8.8 1.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Ank_4 PF13637.1 EEQ31250.1 - 1.2e-12 48.0 0.9 2.1e-10 40.8 0.3 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ31250.1 - 2.5e-07 30.9 0.1 0.0012 19.1 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ31250.1 - 1.3e-05 25.2 4.8 0.00072 19.7 0.2 3.8 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ31250.1 - 0.0013 18.8 3.6 0.042 14.0 0.1 4.3 4 1 0 4 4 4 1 Ankyrin repeat KilA-N PF04383.8 EEQ31250.1 - 0.0063 16.1 0.2 0.0063 16.1 0.1 2.7 2 1 0 2 2 2 1 KilA-N domain Ank PF00023.25 EEQ31250.1 - 0.074 12.9 7.3 0.32 10.8 0.2 4.4 4 1 0 4 4 4 0 Ankyrin repeat Baculo_PEP_C PF04513.7 EEQ31250.1 - 0.18 11.6 2.9 0.35 10.6 1.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Complex1_LYR_1 PF13232.1 EEQ31251.1 - 4e-08 33.3 1.1 1e-07 32.0 0.8 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEQ31251.1 - 8.8e-08 31.8 0.7 2.2e-07 30.5 0.5 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_10 PF05971.7 EEQ31252.1 - 3.1e-40 138.2 0.8 1.3e-28 100.0 0.0 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF890) Isochorismatase PF00857.15 EEQ31253.1 - 1.7e-20 73.7 0.1 2e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Pribosyltran_N PF13793.1 EEQ31254.1 - 3.7e-37 126.5 0.0 1.6e-34 118.1 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEQ31254.1 - 2.7e-35 121.8 0.4 1.9e-30 106.0 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEQ31254.1 - 2.5e-07 30.4 0.7 5.3e-05 22.9 0.1 2.7 3 0 0 3 3 3 2 Phosphoribosyl transferase domain CbiJ PF02571.9 EEQ31254.1 - 0.06 12.6 0.1 0.18 11.0 0.0 1.8 3 0 0 3 3 3 0 Precorrin-6x reductase CbiJ/CobK NAD_binding_7 PF13241.1 EEQ31255.1 - 6.6e-33 113.0 0.2 1.5e-32 111.9 0.2 1.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EEQ31255.1 - 5e-30 102.6 0.0 8.3e-30 101.9 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EEQ31255.1 - 1.1e-15 56.3 0.1 2e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 EEQ31255.1 - 0.07 12.9 1.2 0.13 12.1 0.1 1.9 1 1 1 2 2 2 0 ThiF family Shikimate_DH PF01488.15 EEQ31255.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sec7 PF01369.15 EEQ31256.1 - 4.1e-63 212.5 0.1 1.4e-62 210.7 0.1 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EEQ31256.1 - 1e-51 174.6 7.0 1e-51 174.6 4.9 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EEQ31256.1 - 5.3e-31 105.9 0.1 5.3e-31 105.9 0.1 5.1 8 0 0 8 8 8 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 EEQ31257.1 - 8.5e-75 250.9 0.0 1.1e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEQ31257.1 - 3.6e-17 61.7 2.4 3.7e-17 61.7 0.3 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EEQ31257.1 - 3.1e-14 52.3 1.0 8.7e-14 50.8 0.7 1.9 1 0 0 1 1 1 1 e3 binding domain Rotamase PF00639.16 EEQ31258.1 - 0.00054 20.6 0.7 0.00079 20.1 0.5 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain GOLGA2L5 PF15070.1 EEQ31258.1 - 0.0023 16.5 1.7 0.0025 16.3 1.2 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 SR-25 PF10500.4 EEQ31258.1 - 0.0064 15.9 7.2 0.008 15.6 5.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 EEQ31258.1 - 0.0076 15.6 11.9 0.0096 15.3 8.3 1.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal AD PF09793.4 EEQ31258.1 - 0.039 13.8 1.2 0.064 13.0 0.8 1.4 1 0 0 1 1 1 0 Anticodon-binding domain DUF883 PF05957.8 EEQ31258.1 - 0.16 12.3 3.0 0.33 11.3 2.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.3 EEQ31258.1 - 0.24 10.4 5.5 0.32 10.0 3.8 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3337 PF11816.3 EEQ31258.1 - 0.37 10.1 6.3 0.45 9.8 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) YtxH PF12732.2 EEQ31258.1 - 1.1 9.6 9.8 0.12 12.8 3.3 2.0 2 1 0 2 2 2 0 YtxH-like protein Pkinase PF00069.20 EEQ31259.1 - 3.6e-23 82.0 0.0 5.2e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31259.1 - 9.9e-19 67.4 0.0 2.1e-18 66.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ31259.1 - 0.035 13.0 0.0 0.097 11.6 0.0 1.7 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 EEQ31261.1 - 1.2e-17 64.4 0.0 1.5e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ31261.1 - 5.7e-05 22.7 0.0 9.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ31261.1 - 0.14 11.2 0.0 0.5 9.4 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain 6PF2K PF01591.13 EEQ31263.1 - 3.3e-79 265.0 0.2 5.9e-79 264.2 0.0 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEQ31263.1 - 2e-33 115.7 0.0 4.8e-33 114.4 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Vps39_1 PF10366.4 EEQ31263.1 - 5.1e-29 100.4 0.0 2.1e-28 98.4 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 EEQ31263.1 - 7e-19 68.2 0.0 1.5e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 EEQ31263.1 - 1.5e-12 47.6 0.0 8.1e-12 45.2 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 AAA_33 PF13671.1 EEQ31263.1 - 4.9e-08 32.9 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.23 EEQ31263.1 - 0.025 14.1 0.7 40 4.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Gon7 PF08738.5 EEQ31264.1 - 3.7e-14 52.5 1.6 1.7e-13 50.4 1.1 1.8 1 1 0 1 1 1 1 Gon7 family Ank_2 PF12796.2 EEQ31265.1 - 7.9e-100 327.3 19.1 1.2e-16 60.8 0.2 6.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ31265.1 - 1.3e-84 274.0 12.6 7.7e-06 25.4 0.0 14.4 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 EEQ31265.1 - 8.1e-68 223.7 5.6 5e-13 49.1 0.1 9.8 6 2 5 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ31265.1 - 3.5e-59 195.4 12.0 2e-10 40.5 0.0 12.5 1 1 10 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ31265.1 - 5.5e-57 184.0 7.7 0.00059 19.8 0.0 13.6 13 0 0 13 13 13 12 Ankyrin repeat HbrB PF08539.6 EEQ31266.1 - 5.7e-54 182.2 0.0 9.1e-54 181.5 0.0 1.3 1 0 0 1 1 1 1 HbrB-like ROK PF00480.15 EEQ31267.1 - 0.065 13.0 0.5 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 ROK family Peptidase_S64 PF08192.6 EEQ31269.1 - 2.1e-06 26.3 0.0 0.0017 16.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S64 Trypsin_2 PF13365.1 EEQ31269.1 - 0.0019 18.1 0.0 0.076 13.0 0.0 3.0 1 1 1 2 2 2 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.16 EEQ31269.1 - 0.0056 16.0 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S32 PF05579.8 EEQ31269.1 - 0.0097 14.9 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.4 EEQ31269.1 - 0.28 9.5 0.4 0.42 8.9 0.3 1.1 1 0 0 1 1 1 0 Peptidase S46 Raptor_N PF14538.1 EEQ31270.1 - 0.056 13.2 0.6 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain V-SNARE_C PF12352.3 EEQ31271.1 - 1.1e-15 57.4 1.0 2.2e-15 56.4 0.7 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EEQ31271.1 - 8.3e-06 25.4 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Sec20 BAR_2 PF10455.4 EEQ31271.1 - 0.0052 15.7 0.1 0.0072 15.2 0.1 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Sigma70_r4 PF04545.11 EEQ31271.1 - 0.027 13.7 0.1 0.053 12.8 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF607 PF04678.8 EEQ31271.1 - 0.056 13.3 0.3 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Antimicrobial10 PF08105.6 EEQ31271.1 - 0.098 12.2 0.5 0.21 11.2 0.3 1.5 1 0 0 1 1 1 0 Metchnikowin family CoA_binding_3 PF13727.1 EEQ31272.1 - 0.23 11.2 7.8 0.042 13.6 0.8 2.8 4 0 0 4 4 4 0 CoA-binding domain Ldh_1_C PF02866.13 EEQ31273.1 - 3e-44 150.8 0.0 4.6e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EEQ31273.1 - 2.5e-43 147.2 0.0 3.7e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EEQ31273.1 - 0.00047 18.9 0.0 0.00068 18.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EEQ31273.1 - 0.054 12.8 0.2 0.28 10.4 0.2 2.1 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.19 EEQ31273.1 - 0.065 13.5 0.4 0.56 10.5 0.0 2.6 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.24 EEQ31274.1 - 1.8e-16 60.5 0.8 6.5e-16 58.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEQ31274.1 - 1.6e-05 24.5 0.1 6.4e-05 22.6 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EEQ31274.1 - 0.0002 21.1 0.0 0.00058 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ31274.1 - 0.00023 21.2 0.5 0.0053 16.8 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ31274.1 - 0.0046 16.9 2.1 0.0094 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EEQ31274.1 - 0.032 14.0 0.1 0.032 14.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain CDC27 PF09507.5 EEQ31274.1 - 0.25 10.5 65.9 0.44 9.7 45.7 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Myb_DNA-bind_3 PF12776.2 EEQ31275.1 - 0.0004 20.9 0.1 1.1 9.8 0.0 2.3 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EEQ31275.1 - 0.015 15.2 1.2 5.2 7.0 0.3 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EEQ31275.1 - 0.13 12.4 1.7 0.8 9.8 1.2 2.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.20 EEQ31276.1 - 7.2e-15 54.8 0.0 1.9e-14 53.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31276.1 - 1.8e-12 46.9 0.0 1.2e-11 44.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ31276.1 - 0.02 13.8 0.0 0.14 11.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like MFS_1 PF07690.11 EEQ31277.1 - 1.5e-13 50.1 12.0 1.5e-13 50.1 8.3 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily LSM PF01423.17 EEQ31280.1 - 3.4e-17 61.7 0.0 4.5e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEQ31280.1 - 0.082 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DSPc PF00782.15 EEQ31281.1 - 9.9e-11 41.3 0.0 1.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEQ31281.1 - 1.5e-05 24.4 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEQ31281.1 - 0.017 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.7 EEQ31281.1 - 0.06 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EEQ31281.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate PPR_3 PF13812.1 EEQ31282.1 - 5.1e-18 63.7 2.8 0.02 15.1 0.0 9.3 10 0 0 10 10 10 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEQ31282.1 - 6.6e-15 54.8 0.0 0.042 13.8 0.0 6.8 4 2 3 7 7 7 5 PPR repeat family PPR PF01535.15 EEQ31282.1 - 1.7e-10 40.1 3.4 0.22 11.5 0.0 7.2 8 0 0 8 8 8 2 PPR repeat TPR_14 PF13428.1 EEQ31282.1 - 0.0032 17.9 0.0 80 4.2 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ31282.1 - 0.019 14.8 0.1 4.3 7.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ31282.1 - 0.085 12.8 0.4 51 3.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NB-ARC PF00931.17 EEQ31282.1 - 0.086 11.6 0.1 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain F-box-like PF12937.2 EEQ31283.1 - 2.7e-05 23.8 1.5 0.0001 21.9 0.3 2.4 2 0 0 2 2 2 1 F-box-like LysM PF01476.15 EEQ31284.1 - 1.6e-27 95.0 3.2 2.5e-07 30.4 0.0 5.9 5 1 0 5 5 5 4 LysM domain UPF0203 PF05254.7 EEQ31284.1 - 0.011 15.5 12.1 0.38 10.6 0.4 4.7 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0203) Aspzincin_M35 PF14521.1 EEQ31285.1 - 0.00017 22.1 0.0 0.00026 21.5 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.10 EEQ31285.1 - 0.0019 16.9 0.0 0.0033 16.1 0.0 1.3 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Glyco_hydro_18 PF00704.23 EEQ31286.1 - 4.6e-72 243.3 3.5 7.4e-72 242.6 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PLA2_B PF01735.13 EEQ31287.1 - 3.2e-27 94.8 0.0 5.2e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.10 EEQ31288.1 - 9.9e-76 254.9 0.0 1.7e-75 254.1 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Laminin_II PF06009.7 EEQ31288.1 - 0.021 14.5 2.6 2.5 7.8 0.2 2.6 2 0 0 2 2 2 0 Laminin Domain II Glycophorin_A PF01102.13 EEQ31289.1 - 0.016 14.9 1.8 0.021 14.5 0.0 2.2 2 0 0 2 2 2 0 Glycophorin A BCDHK_Adom3 PF10436.4 EEQ31290.1 - 2e-67 225.7 0.0 2.7e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EEQ31290.1 - 1.1e-17 63.6 0.0 7.7e-17 61.0 0.0 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EEQ31290.1 - 0.0023 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 EEQ31290.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family SKN1 PF03935.10 EEQ31293.1 - 2e-192 639.8 0.2 2.3e-168 560.4 0.9 2.0 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Neurensin PF14927.1 EEQ31293.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Neurensin NuiA PF07924.6 EEQ31294.1 - 0.11 12.4 0.0 0.75 9.7 0.0 2.1 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein Ribosomal_L3 PF00297.17 EEQ31295.1 - 5.8e-114 379.9 7.8 7.4e-114 379.5 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 zf-C2HC PF01530.13 EEQ31295.1 - 0.081 12.6 0.8 0.19 11.4 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2HC type PGAP1 PF07819.8 EEQ31296.1 - 4e-08 33.1 0.1 1e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 EEQ31296.1 - 1.6e-05 24.2 0.3 6e-05 22.4 0.1 1.8 1 1 1 2 2 2 1 Putative serine esterase (DUF676) LCAT PF02450.10 EEQ31296.1 - 0.00093 18.2 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EEQ31296.1 - 0.003 17.4 0.6 0.02 14.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family TPR_1 PF00515.23 EEQ31297.1 - 1.2e-41 138.6 32.9 4.4e-08 32.4 0.0 11.2 10 2 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ31297.1 - 2.1e-38 127.1 23.0 6.9e-06 25.5 0.0 10.8 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ31297.1 - 2.8e-38 129.4 22.0 1.1e-10 40.9 0.4 6.4 3 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 EEQ31297.1 - 2.5e-30 101.9 24.7 2.7e-05 23.6 0.6 9.2 8 1 2 10 10 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ31297.1 - 4.9e-24 84.0 22.9 3.8e-08 33.1 0.6 7.5 2 2 5 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ31297.1 - 8.1e-24 81.7 14.6 0.00021 21.2 0.1 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ31297.1 - 9.1e-23 80.3 34.3 1.5e-06 28.7 0.1 7.4 5 2 3 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ31297.1 - 1.4e-18 65.7 30.5 0.00012 22.4 0.1 9.8 5 3 6 11 11 10 7 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ31297.1 - 2.3e-17 62.1 27.1 0.0017 18.7 0.0 10.1 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ31297.1 - 2.9e-17 61.0 19.0 0.008 15.8 0.1 8.9 8 2 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ31297.1 - 2.7e-12 46.8 34.4 0.0022 18.2 0.1 6.8 5 2 3 8 8 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EEQ31297.1 - 1.1e-10 41.4 11.3 1.9e-08 34.2 1.7 4.1 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEQ31297.1 - 1.7e-09 37.3 19.4 0.0029 17.4 0.2 7.3 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ31297.1 - 2.3e-07 30.1 10.3 0.0011 18.1 1.5 5.1 1 1 3 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.4 EEQ31297.1 - 0.0021 17.5 4.1 1.1 8.6 1.5 3.1 2 2 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 EEQ31297.1 - 0.084 12.8 13.8 19 5.3 0.1 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EEQ31297.1 - 7.9 6.6 17.6 1.4 9.0 0.1 4.9 4 1 2 6 6 4 0 Tetratricopeptide repeat NUC173 PF08161.7 EEQ31299.1 - 7e-76 253.9 0.1 4.6e-74 248.0 0.1 2.7 2 0 0 2 2 2 2 NUC173 domain RasGAP PF00616.14 EEQ31299.1 - 0.019 14.6 1.2 0.7 9.5 0.0 2.4 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase LSM PF01423.17 EEQ31300.1 - 0.0048 16.4 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 LSM domain MDM1 PF15501.1 EEQ31300.1 - 0.033 13.1 3.3 0.17 10.7 0.0 1.9 2 0 0 2 2 2 0 Nuclear protein MDM1 PAT1 PF09770.4 EEQ31300.1 - 0.038 12.2 8.8 0.038 12.2 6.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF334 PF03904.8 EEQ31300.1 - 0.064 12.5 0.3 0.19 11.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF334) Pex14_N PF04695.8 EEQ31300.1 - 4.7 7.2 7.9 0.88 9.6 3.1 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zn_clus PF00172.13 EEQ31301.1 - 4.3e-08 32.9 10.8 6.9e-08 32.2 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEQ31301.1 - 4.3e-05 22.2 0.0 7.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EEQ31302.1 - 2.7e-46 157.8 1.6 3.6e-46 157.4 1.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DoxX PF07681.7 EEQ31302.1 - 0.026 14.9 2.3 0.026 14.9 1.6 2.8 4 1 0 4 4 4 0 DoxX DUF3040 PF11239.3 EEQ31302.1 - 2.5 8.2 7.5 14 5.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) 6PGD PF00393.14 EEQ31303.1 - 1.8e-53 181.6 0.0 3.3e-53 180.7 0.0 1.4 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EEQ31303.1 - 4.3e-33 114.4 0.1 7.3e-33 113.7 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EEQ31303.1 - 1.5e-07 31.2 0.1 2.8e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EEQ31303.1 - 5.5e-07 29.4 0.1 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EEQ31303.1 - 0.00013 22.1 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EEQ31303.1 - 0.00057 19.3 0.5 0.0024 17.2 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EEQ31303.1 - 0.00082 19.7 0.1 0.0026 18.1 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EEQ31303.1 - 0.0031 16.9 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EEQ31303.1 - 0.026 13.7 1.1 0.032 13.3 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 EEQ31303.1 - 0.058 12.2 0.3 0.1 11.4 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ31303.1 - 0.074 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-C2H2_jaz PF12171.3 EEQ31304.1 - 0.023 14.8 0.9 0.082 13.0 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.9 EEQ31304.1 - 0.062 12.9 0.8 0.13 11.9 0.3 1.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 EEQ31304.1 - 0.075 13.3 6.3 0.12 12.6 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ31304.1 - 0.51 10.8 5.6 0.84 10.1 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type ArsC PF03960.10 EEQ31306.1 - 0.11 12.5 0.0 14 5.8 0.0 2.4 1 1 1 2 2 2 0 ArsC family DUF3125 PF11323.3 EEQ31306.1 - 0.47 10.2 2.3 8.2 6.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3125) FAD_binding_4 PF01565.18 EEQ31308.1 - 3.9e-18 65.2 3.8 7.7e-18 64.3 2.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ31308.1 - 4e-08 33.0 0.0 9.9e-08 31.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like DUF3579 PF12112.3 EEQ31308.1 - 0.038 13.8 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) Cytokin-bind PF09265.5 EEQ31308.1 - 0.14 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Ribonuclease_3 PF00636.21 EEQ31309.1 - 1.4e-39 135.0 0.0 1.1e-18 67.7 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.9 EEQ31309.1 - 2.2e-21 75.4 0.1 5.1e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 EEQ31309.1 - 2.4e-19 69.4 0.0 5.2e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribonucleas_3_3 PF14622.1 EEQ31309.1 - 2.6e-19 69.4 0.4 1.6e-09 37.7 0.1 4.0 4 1 0 4 4 4 2 Ribonuclease-III-like Helicase_C PF00271.26 EEQ31309.1 - 3.9e-14 52.2 0.0 1.1e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ31309.1 - 2.1e-11 43.9 0.0 4.4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 EEQ31309.1 - 0.0045 17.5 0.0 0.058 13.9 0.0 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Proteasome PF00227.21 EEQ31310.1 - 2.6e-56 189.9 0.0 1.8e-31 108.9 0.0 2.2 1 1 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EEQ31310.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_2 PF00891.13 EEQ31310.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RINGv PF12906.2 EEQ31311.1 - 1.5e-09 37.7 2.6 9.8e-09 35.1 0.5 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EEQ31311.1 - 0.0038 17.0 3.1 0.022 14.5 0.5 2.2 2 0 0 2 2 2 1 Ring finger domain DUF4379 PF14311.1 EEQ31311.1 - 0.026 14.3 0.1 0.079 12.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) PHD PF00628.24 EEQ31311.1 - 0.96 9.1 5.6 0.34 10.6 1.7 1.8 2 0 0 2 2 2 0 PHD-finger YiaAB PF05360.9 EEQ31311.1 - 7.5 6.1 7.5 0.44 10.1 1.1 1.9 2 0 0 2 2 2 0 yiaA/B two helix domain Fungal_trans PF04082.13 EEQ31314.1 - 4.1e-09 35.7 1.5 4.1e-09 35.7 1.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ31314.1 - 0.00087 19.1 12.7 0.0019 18.0 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EEQ31316.1 - 2.5e-85 286.7 29.4 3.2e-85 286.3 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ31316.1 - 7.4e-12 44.6 48.0 4.2e-11 42.1 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 EEQ31319.1 - 2.4e-51 169.8 22.1 4.4e-09 35.8 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EEQ31319.1 - 1.6e-10 40.5 0.6 3.1e-10 39.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EEQ31319.1 - 1.2e-09 36.9 7.9 0.0027 15.9 0.9 4.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 EEQ31319.1 - 0.00059 19.4 0.6 0.0017 17.9 0.4 1.9 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EEQ31319.1 - 0.011 14.5 0.9 0.16 10.6 0.0 2.8 1 1 0 2 2 2 0 Nup133 N terminal like PQQ_3 PF13570.1 EEQ31319.1 - 0.02 15.1 0.5 44 4.5 0.0 4.6 4 1 1 5 5 5 0 PQQ-like domain PQQ_2 PF13360.1 EEQ31319.1 - 0.034 13.6 2.6 0.31 10.4 0.3 2.9 1 1 1 2 2 2 0 PQQ-like domain PyrBI_leader PF08052.6 EEQ31319.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 PyrBI operon leader peptide Zip PF02535.17 EEQ31320.1 - 5.9e-39 133.9 13.2 8.4e-30 103.8 2.7 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter DUF1183 PF06682.7 EEQ31320.1 - 2 7.9 4.2 4.1 6.9 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Transp_cyt_pur PF02133.10 EEQ31321.1 - 3.5e-93 312.5 36.5 3.9e-91 305.7 25.3 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.7 EEQ31322.1 - 2.9e-123 410.9 0.6 1.1e-122 408.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EEQ31322.1 - 5.2e-50 170.1 11.2 4.4e-49 167.1 3.5 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEQ31322.1 - 4.6e-26 91.3 12.5 1.4e-17 63.8 0.8 5.2 3 2 1 4 4 4 3 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EEQ31322.1 - 0.00035 19.0 3.4 0.064 11.5 0.2 2.7 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.15 EEQ31322.1 - 0.00081 18.7 0.3 0.00081 18.7 0.2 2.7 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EEQ31322.1 - 0.029 13.2 0.5 2.6 6.9 0.0 2.8 3 0 0 3 3 3 0 StbA protein Hat1_N PF10394.4 EEQ31323.1 - 9e-47 159.1 0.1 2.1e-46 157.9 0.0 1.7 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus ENT PF03735.9 EEQ31323.1 - 0.0091 15.7 0.4 1.6 8.5 0.1 3.2 3 0 0 3 3 3 1 ENT domain CtIP_N PF10482.4 EEQ31324.1 - 0.012 15.4 1.6 0.019 14.7 1.1 1.2 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain adh_short PF00106.20 EEQ31326.1 - 3.3e-18 66.1 0.0 5.3e-18 65.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ31326.1 - 1.9e-06 27.6 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ31326.1 - 3.9e-05 23.5 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EEQ31326.1 - 0.0062 16.6 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EEQ31326.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 EEQ31326.1 - 0.057 12.5 0.0 0.98 8.4 0.0 2.2 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EEQ31326.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Terpene_synth_C PF03936.11 EEQ31327.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain p450 PF00067.17 EEQ31328.1 - 9.6e-55 185.9 0.0 1.3e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEQ31329.1 - 2.8e-74 250.3 0.0 3.6e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trypsin_2 PF13365.1 EEQ31332.1 - 7.4e-05 22.7 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.6 EEQ31332.1 - 0.00018 20.0 0.1 0.06 11.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S32 PF05579.8 EEQ31332.1 - 0.077 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.4 EEQ31332.1 - 0.21 9.9 0.1 0.29 9.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF155 PF02582.9 EEQ31334.1 - 9.9e-52 175.3 0.2 1.5e-51 174.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 U3_snoRNA_assoc PF08297.6 EEQ31335.1 - 2.7e-11 43.5 0.0 2.7e-11 43.5 0.0 4.0 3 2 0 3 3 3 1 U3 snoRNA associated Borrelia_P83 PF05262.6 EEQ31335.1 - 0.28 9.3 18.0 0.45 8.7 12.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Nop53 PF07767.6 EEQ31335.1 - 1.1 8.2 31.0 0.041 12.8 16.6 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CTK3 PF12243.3 EEQ31336.1 - 3.8e-55 185.3 0.1 6e-55 184.6 0.1 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EEQ31336.1 - 1.1e-20 73.4 10.6 2.3e-20 72.3 7.3 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus P5CR_dimer PF14748.1 EEQ31337.1 - 5.8e-30 103.4 2.1 9.2e-30 102.8 1.5 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EEQ31337.1 - 9.5e-10 38.7 0.1 3.6e-07 30.5 0.0 3.0 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Voltage_CLC PF00654.15 EEQ31338.1 - 5.1e-90 302.0 23.4 5.1e-90 302.0 16.3 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EEQ31338.1 - 1.4e-09 37.5 0.0 6.7e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain AAA_5 PF07728.9 EEQ31339.1 - 2.4e-135 445.2 0.0 1.9e-23 82.7 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EEQ31339.1 - 5.2e-31 107.5 0.0 0.0001 22.4 0.0 6.9 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EEQ31339.1 - 2.6e-30 104.6 0.0 2.3e-11 43.4 0.0 7.3 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ31339.1 - 6.9e-22 78.3 18.2 0.00016 21.7 0.1 8.7 8 0 0 8 8 7 6 AAA ATPase domain AAA_17 PF13207.1 EEQ31339.1 - 1.8e-20 73.9 0.0 0.015 16.1 0.0 7.2 6 0 0 6 6 6 4 AAA domain AAA_33 PF13671.1 EEQ31339.1 - 3.6e-20 72.3 0.0 0.014 15.2 0.0 7.8 6 2 0 6 6 6 4 AAA domain AAA_22 PF13401.1 EEQ31339.1 - 4.8e-20 72.0 4.2 0.077 13.1 0.0 9.0 9 2 0 9 9 7 5 AAA domain Sigma54_activat PF00158.21 EEQ31339.1 - 4.2e-18 65.3 0.0 0.014 14.9 0.0 6.5 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_14 PF13173.1 EEQ31339.1 - 1.8e-17 63.4 0.0 8.5e-05 22.4 0.0 7.5 7 0 0 7 7 7 2 AAA domain AAA_18 PF13238.1 EEQ31339.1 - 5.7e-17 62.2 0.8 0.13 12.5 0.0 7.6 6 0 0 6 6 6 3 AAA domain Sigma54_activ_2 PF14532.1 EEQ31339.1 - 2.5e-15 56.7 1.6 0.0057 16.6 0.0 7.1 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_19 PF13245.1 EEQ31339.1 - 1.6e-14 53.3 2.3 0.11 12.2 0.0 6.5 6 0 0 6 6 6 3 Part of AAA domain Mg_chelatase PF01078.16 EEQ31339.1 - 3.1e-14 52.6 2.3 0.52 9.4 0.0 9.4 9 1 0 9 9 9 2 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 EEQ31339.1 - 4.3e-14 52.1 5.1 0.058 13.0 0.0 7.0 7 0 0 7 7 7 4 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EEQ31339.1 - 9.1e-14 51.0 7.8 0.0052 15.8 0.0 7.6 8 0 0 8 8 7 4 Zeta toxin ABC_tran PF00005.22 EEQ31339.1 - 5.4e-13 49.4 7.2 0.041 14.1 0.0 7.3 7 0 0 7 7 6 3 ABC transporter RNA_helicase PF00910.17 EEQ31339.1 - 1.6e-11 44.3 0.7 2.3 8.4 0.0 6.7 6 0 0 6 6 6 2 RNA helicase NACHT PF05729.7 EEQ31339.1 - 6e-11 42.2 7.2 0.26 10.9 0.0 7.1 7 0 0 7 7 6 3 NACHT domain RuvB_N PF05496.7 EEQ31339.1 - 7.2e-11 41.5 3.2 0.13 11.3 0.0 6.3 6 1 0 6 6 6 3 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EEQ31339.1 - 7.6e-11 41.3 2.3 0.17 10.7 0.0 6.4 6 0 0 6 6 6 3 Protein of unknown function (DUF815) Miro PF08477.8 EEQ31339.1 - 1.6e-10 41.5 3.5 3 8.3 0.0 6.7 6 0 0 6 6 6 1 Miro-like protein AAA_25 PF13481.1 EEQ31339.1 - 3.5e-10 39.6 0.4 0.84 9.0 0.0 5.8 6 0 0 6 6 5 3 AAA domain T2SE PF00437.15 EEQ31339.1 - 8.6e-10 37.9 2.6 0.09 11.6 0.0 5.3 5 0 0 5 5 5 3 Type II/IV secretion system protein AAA_29 PF13555.1 EEQ31339.1 - 1.2e-09 37.5 0.3 0.65 9.5 0.0 6.5 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EEQ31339.1 - 1.9e-09 37.6 5.6 0.16 11.9 0.0 6.5 6 0 0 6 6 6 3 AAA domain SRP54 PF00448.17 EEQ31339.1 - 4.9e-09 35.9 1.1 0.95 8.8 0.0 5.9 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 EEQ31339.1 - 7e-09 35.3 0.9 0.23 10.9 0.0 6.3 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 EEQ31339.1 - 7.3e-08 32.0 0.2 1.4 8.3 0.0 6.1 6 0 0 6 6 6 1 IstB-like ATP binding protein DUF258 PF03193.11 EEQ31339.1 - 3.7e-07 29.4 6.5 1.6 7.8 0.1 5.9 6 0 0 6 6 6 2 Protein of unknown function, DUF258 MobB PF03205.9 EEQ31339.1 - 1.5e-06 27.9 0.5 17 5.0 0.0 6.2 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B TIP49 PF06068.8 EEQ31339.1 - 1.1e-05 24.4 2.7 2.4 6.7 0.0 5.0 5 0 0 5 5 5 1 TIP49 C-terminus NTPase_1 PF03266.10 EEQ31339.1 - 2.6e-05 24.0 2.3 0.66 9.6 0.0 5.2 6 0 0 6 6 4 1 NTPase AAA_7 PF12775.2 EEQ31339.1 - 0.0001 21.5 1.0 1.7 7.6 0.0 4.9 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 MMR_HSR1 PF01926.18 EEQ31339.1 - 0.00015 21.7 1.1 23 4.9 0.0 6.0 6 0 0 6 6 6 0 50S ribosome-binding GTPase ResIII PF04851.10 EEQ31339.1 - 0.00046 20.0 7.6 0.29 10.9 0.0 5.5 6 0 0 6 6 5 1 Type III restriction enzyme, res subunit KaiC PF06745.8 EEQ31339.1 - 0.00064 18.9 0.3 17 4.4 0.0 4.9 5 0 0 5 5 4 0 KaiC PhoH PF02562.11 EEQ31339.1 - 0.0018 17.5 0.7 4.9 6.3 0.0 4.6 5 0 0 5 5 5 0 PhoH-like protein AAA_6 PF12774.2 EEQ31339.1 - 0.0022 17.5 0.0 1.4e+02 1.8 0.0 6.5 7 1 0 7 7 6 0 Hydrolytic ATP binding site of dynein motor region D1 cobW PF02492.14 EEQ31339.1 - 0.0054 16.1 5.9 7.3 5.9 0.0 5.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EEQ31339.1 - 0.018 14.5 6.4 13 5.1 0.0 5.4 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 EEQ31339.1 - 0.024 14.1 0.1 10 5.5 0.0 4.0 5 0 0 5 5 5 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 EEQ31339.1 - 0.041 13.4 4.5 1.3 8.6 0.0 4.7 6 1 0 6 6 4 0 Chloramphenicol phosphotransferase-like protein Ras PF00071.17 EEQ31339.1 - 0.55 9.6 2.5 58 3.0 0.0 4.3 5 0 0 5 5 5 0 Ras family ATP-grasp_4 PF13535.1 EEQ31340.1 - 1.9e-15 57.0 0.0 3.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EEQ31340.1 - 2.1e-09 37.4 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEQ31340.1 - 0.0031 16.3 0.0 0.025 13.3 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EEQ31340.1 - 0.085 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DevR PF01905.11 EEQ31340.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 APH PF01636.18 EEQ31341.1 - 1.3e-15 57.8 0.0 1.8e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ31341.1 - 0.00012 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ31341.1 - 0.00023 19.9 0.2 0.00043 19.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEQ31341.1 - 0.0025 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EEQ31341.1 - 0.081 12.2 0.2 0.25 10.6 0.1 1.7 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EEQ31341.1 - 0.13 11.4 0.0 0.86 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain DUF3716 PF12511.3 EEQ31342.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) PRCC PF10253.4 EEQ31343.1 - 5.5e-34 118.4 6.4 5.5e-34 118.4 4.4 2.7 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting BRF1 PF07741.8 EEQ31344.1 - 0.00072 19.7 18.2 0.0021 18.2 6.1 3.1 2 1 0 2 2 2 2 Brf1-like TBP-binding domain DUF1777 PF08648.7 EEQ31344.1 - 6.6 6.4 33.3 1.8 8.2 5.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Lectin_leg-like PF03388.8 EEQ31345.1 - 1.9e-61 207.1 0.0 2.7e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EEQ31345.1 - 0.027 13.8 0.0 0.69 9.2 0.0 2.2 2 0 0 2 2 2 0 Legume lectin domain PBP1_TM PF14812.1 EEQ31345.1 - 0.051 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-Tim10_DDP PF02953.10 EEQ31346.1 - 1.3e-21 75.6 2.1 2e-21 75.0 1.5 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.20 EEQ31347.1 - 2.9e-70 236.4 0.0 3.9e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31347.1 - 7.9e-37 126.7 0.0 1.1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ31347.1 - 5.8e-07 28.7 0.0 1.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EEQ31347.1 - 0.045 12.5 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EEQ31347.1 - 0.061 13.0 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEQ31347.1 - 0.099 11.9 0.2 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SIN1 PF05422.7 EEQ31348.1 - 1.2e-29 103.2 0.0 1.7e-16 59.8 0.0 2.3 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EEQ31348.1 - 0.0011 18.8 0.1 0.0023 17.8 0.1 1.4 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Mito_carr PF00153.22 EEQ31350.1 - 2e-13 49.8 0.1 4.2e-07 29.5 0.1 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Peptidase_M28 PF04389.12 EEQ31351.1 - 7.9e-33 113.6 0.7 1.1e-32 113.1 0.5 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EEQ31351.1 - 0.00081 18.9 0.2 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EEQ31351.1 - 0.044 13.0 0.1 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Nicastrin Histone PF00125.19 EEQ31352.1 - 2e-15 56.6 0.2 2.4e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEQ31352.1 - 6.4e-05 23.0 0.1 9.1e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EEQ31352.1 - 9e-05 22.3 0.1 0.00013 21.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EEQ31352.1 - 0.00016 21.6 0.1 0.00034 20.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEQ31352.1 - 0.007 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EEQ31352.1 - 0.035 13.3 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 EEQ31352.1 - 0.043 14.0 0.1 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 EEQ31352.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBM_21 PF03370.8 EEQ31353.1 - 8.1e-31 106.3 0.0 2.7e-30 104.6 0.0 1.9 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit DUF4095 PF13338.1 EEQ31354.1 - 0.022 14.8 0.3 0.03 14.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) SH3_9 PF14604.1 EEQ31355.1 - 5.7e-05 22.6 0.2 5.7e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EEQ31355.1 - 0.072 12.4 0.1 0.2 11.0 0.1 1.7 1 0 0 1 1 1 0 SH3 domain HEAT_2 PF13646.1 EEQ31356.1 - 4.4e-52 174.3 63.3 2.3e-11 43.8 1.2 7.4 1 1 8 9 9 9 9 HEAT repeats HEAT PF02985.17 EEQ31356.1 - 7.9e-36 118.9 18.8 0.0011 18.8 0.1 13.6 14 0 0 14 14 14 9 HEAT repeat HEAT_EZ PF13513.1 EEQ31356.1 - 3.9e-27 93.9 44.5 0.00012 22.4 1.2 10.4 8 2 2 10 10 10 8 HEAT-like repeat Arm PF00514.18 EEQ31356.1 - 7.3e-14 50.9 16.9 0.18 11.7 0.1 8.7 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat NACHT PF05729.7 EEQ31356.1 - 3e-13 49.7 0.0 6.9e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EEQ31356.1 - 4.4e-05 22.4 0.0 0.00021 20.2 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 EEQ31356.1 - 0.00011 23.0 0.3 0.00064 20.5 0.0 2.6 2 0 0 2 2 1 1 AAA domain G-alpha PF00503.15 EEQ31356.1 - 0.0049 15.5 0.0 0.044 12.4 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 EEQ31356.1 - 0.0069 16.5 0.0 0.082 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain DNA_alkylation PF08713.6 EEQ31356.1 - 0.0077 15.7 6.3 0.33 10.4 0.2 4.3 5 0 0 5 5 5 1 DNA alkylation repair enzyme AAA_18 PF13238.1 EEQ31356.1 - 0.015 15.5 0.0 0.072 13.3 0.0 2.2 2 0 0 2 2 1 0 AAA domain Cnd1 PF12717.2 EEQ31356.1 - 0.023 14.5 5.2 78 3.0 0.0 6.4 6 1 2 8 8 8 0 non-SMC mitotic condensation complex subunit 1 ABC_tran PF00005.22 EEQ31356.1 - 0.041 14.1 0.4 0.42 10.9 0.0 2.8 3 0 0 3 3 3 0 ABC transporter AAA_14 PF13173.1 EEQ31356.1 - 0.046 13.6 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Adaptin_N PF01602.15 EEQ31356.1 - 0.084 11.1 3.4 1.4 7.1 0.0 3.6 4 1 1 5 5 5 0 Adaptin N terminal region MobB PF03205.9 EEQ31356.1 - 0.099 12.3 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EEQ31356.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase zf-3CxxC PF13695.1 EEQ31357.1 - 6e-30 103.3 0.2 7.7e-30 103.0 0.2 1.1 1 0 0 1 1 1 1 Zinc-binding domain HNH_2 PF13391.1 EEQ31358.1 - 2.9e-17 62.1 0.0 5.2e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease EBP PF05241.7 EEQ31360.1 - 2.6e-61 206.0 4.6 3e-61 205.8 3.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein Annexin PF00191.15 EEQ31361.1 - 1.2e-56 188.4 0.5 4.4e-15 55.3 0.0 4.2 4 0 0 4 4 4 4 Annexin PsbL PF02419.12 EEQ31363.1 - 1 8.8 4.2 2.2 7.7 2.9 1.5 1 0 0 1 1 1 0 PsbL protein L31 PF09784.4 EEQ31364.1 - 4.7e-46 155.0 1.0 5.2e-46 154.9 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Acyltransferase PF01553.16 EEQ31365.1 - 0.00044 19.6 0.0 0.0067 15.8 0.0 2.2 2 0 0 2 2 2 1 Acyltransferase UPF0154 PF03672.8 EEQ31365.1 - 0.12 12.0 0.1 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DEAD PF00270.24 EEQ31366.1 - 7.8e-41 139.3 1.3 1.4e-40 138.5 0.6 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ31366.1 - 1.5e-22 79.2 0.1 1.3e-11 44.2 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ31366.1 - 3.9e-05 23.5 0.9 0.00014 21.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit F-box-like PF12937.2 EEQ31367.1 - 2.2e-07 30.4 2.0 3.8e-07 29.7 0.4 2.1 2 0 0 2 2 2 1 F-box-like Dabb PF07876.7 EEQ31368.1 - 1.6e-15 57.2 1.4 2e-12 47.3 0.3 2.1 1 1 1 2 2 2 2 Stress responsive A/B Barrel Domain NB-ARC PF00931.17 EEQ31369.1 - 1e-14 54.1 0.0 2.3e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 EEQ31369.1 - 2.8e-11 43.1 6.4 5.7e-11 42.2 1.3 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 EEQ31369.1 - 1.4e-06 28.5 0.0 3.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_11 PF13414.1 EEQ31369.1 - 1.7e-06 27.6 8.7 3.8e-05 23.2 1.3 2.9 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EEQ31369.1 - 2.8e-06 26.7 4.6 0.0057 16.2 0.6 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ31369.1 - 0.00044 19.8 3.2 0.19 11.5 0.7 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ31369.1 - 0.0033 17.9 5.5 0.17 12.6 0.1 4.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ31369.1 - 0.0089 15.8 5.4 0.018 14.9 0.3 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_16 PF13191.1 EEQ31369.1 - 0.016 15.2 0.0 0.2 11.6 0.0 2.7 1 1 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EEQ31369.1 - 0.023 14.3 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase TPR_16 PF13432.1 EEQ31369.1 - 0.031 14.9 11.2 0.28 11.9 0.7 3.4 2 1 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EEQ31369.1 - 0.035 14.2 0.6 0.23 11.6 0.1 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EEQ31369.1 - 0.046 14.0 1.0 0.27 11.5 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ31369.1 - 0.057 13.3 3.1 3.2 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 EEQ31369.1 - 0.14 11.5 0.1 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) PemK PF02452.12 EEQ31370.1 - 0.054 13.6 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 PemK-like protein Kinesin-related PF06548.6 EEQ31371.1 - 0.68 8.4 10.1 0.069 11.7 0.5 2.2 2 0 0 2 2 2 0 Kinesin-related DUF4658 PF15555.1 EEQ31373.1 - 1.8 8.4 13.2 1.1 9.1 5.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) tRNA-synt_1d PF00750.14 EEQ31374.1 - 1.2e-78 264.4 6.4 9.1e-42 143.1 3.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EEQ31374.1 - 3e-28 98.1 0.0 7.6e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EEQ31374.1 - 3.8e-05 24.1 1.2 0.00012 22.4 0.0 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Med9 PF07544.8 EEQ31374.1 - 0.067 12.9 0.8 0.19 11.4 0.5 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 WD40 PF00400.27 EEQ31375.1 - 4.6e-13 48.5 27.6 1.3e-06 28.0 0.6 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat FAD_binding_6 PF00970.19 EEQ31376.1 - 4.4e-29 100.5 0.0 7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEQ31376.1 - 7.9e-28 97.2 0.0 1.3e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EEQ31376.1 - 7.5e-06 25.9 0.0 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EEQ31376.1 - 0.0028 17.5 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4176 PF13780.1 EEQ31376.1 - 0.071 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) DUF3605 PF12239.3 EEQ31377.1 - 1.1e-55 187.8 0.1 1.3e-55 187.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) SMC_N PF02463.14 EEQ31378.1 - 6e-64 215.2 26.9 1.3e-63 214.1 18.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEQ31378.1 - 1.2e-32 112.3 0.5 3.4e-31 107.7 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEQ31378.1 - 5.9e-18 65.8 2.1 2.4e-09 37.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EEQ31378.1 - 3.5e-07 29.6 12.4 3.5e-07 29.6 8.6 3.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EEQ31378.1 - 2e-06 28.2 50.6 2e-06 28.2 35.0 6.6 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EEQ31378.1 - 0.0003 20.2 0.0 0.00073 19.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EEQ31378.1 - 0.25 10.4 28.3 0.99 8.5 2.8 4.8 2 2 3 6 6 6 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EEQ31378.1 - 0.27 9.6 0.0 0.013 14.0 17.9 5.9 3 2 2 5 5 5 0 AAA domain ABC_tran PF00005.22 EEQ31378.1 - 0.4 10.9 0.0 0.4 10.9 0.0 6.0 3 2 1 5 5 5 0 ABC transporter Barstar PF01337.13 EEQ31378.1 - 9.8 6.0 9.8 1.7 8.5 0.0 4.2 4 0 0 4 4 4 0 Barstar (barnase inhibitor) RIO1 PF01163.17 EEQ31379.1 - 6e-72 240.9 0.1 6e-72 240.9 0.1 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EEQ31379.1 - 3.6e-07 30.1 1.4 6.9e-05 22.6 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EEQ31379.1 - 8.7e-05 21.6 0.3 0.00087 18.4 0.2 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEQ31379.1 - 0.073 12.6 0.5 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF3464 PF11947.3 EEQ31379.1 - 0.089 12.2 0.5 0.23 10.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Mlf1IP PF10248.4 EEQ31380.1 - 0.082 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein TraG_N PF07916.6 EEQ31382.1 - 0.17 10.3 0.3 1.3 7.4 0.0 2.0 2 0 0 2 2 2 0 TraG-like protein, N-terminal region WD40 PF00400.27 EEQ31384.1 - 5.2e-64 210.0 25.1 4.1e-11 42.3 0.3 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EEQ31384.1 - 1.9e-15 56.2 0.3 4.3e-15 55.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ31384.1 - 7.4e-12 44.6 0.3 2.1e-11 43.1 0.1 1.9 1 1 0 1 1 1 1 F-box domain Nup160 PF11715.3 EEQ31384.1 - 3.9e-10 38.5 11.9 0.00014 20.2 0.7 5.0 2 2 2 4 4 4 4 Nucleoporin Nup120/160 PRANC PF09372.5 EEQ31384.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Nucleoporin_N PF08801.6 EEQ31384.1 - 0.41 9.3 7.8 2.7 6.6 0.1 2.9 2 1 1 4 4 4 0 Nup133 N terminal like APG17 PF04108.7 EEQ31385.1 - 2.7e-120 401.9 0.0 3.2e-120 401.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF1542 PF07564.6 EEQ31385.1 - 0.02 14.9 0.8 0.02 14.9 0.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Tweety PF04906.8 EEQ31385.1 - 0.052 11.9 0.2 2.8 6.2 0.0 2.6 2 0 0 2 2 2 0 Tweety DinB_2 PF12867.2 EEQ31385.1 - 3.9 7.8 7.0 1.2 9.5 0.2 3.3 2 1 0 2 2 2 0 DinB superfamily CHAT PF12770.2 EEQ31389.1 - 1.1e-31 110.0 0.0 1.9e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EEQ31389.1 - 3.4e-22 78.1 9.5 0.002 18.0 0.0 9.9 4 2 6 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ31389.1 - 1e-17 63.4 11.2 0.0028 17.2 0.1 9.3 3 2 8 11 11 11 6 TPR repeat TPR_10 PF13374.1 EEQ31389.1 - 6e-14 51.4 21.9 0.00014 21.6 0.2 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ31389.1 - 3.1e-07 30.0 5.9 1.8 8.9 0.0 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ31389.1 - 2.4e-06 27.0 0.7 4.9 7.3 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ31389.1 - 7.3e-06 26.1 15.9 21 6.1 0.0 11.2 10 2 4 14 14 13 0 Tetratricopeptide repeat DUF4404 PF14357.1 EEQ31389.1 - 0.0001 22.6 4.0 2.6 8.5 0.0 4.5 4 0 0 4 4 3 1 Domain of unknown function (DUF4404) TPR_16 PF13432.1 EEQ31389.1 - 0.0011 19.6 7.4 0.56 10.9 0.2 6.1 6 1 2 8 8 7 1 Tetratricopeptide repeat Peptidase_C25 PF01364.13 EEQ31389.1 - 0.0018 17.2 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C25 ATP-synt_ab PF00006.20 EEQ31389.1 - 0.07 12.6 0.0 57 3.1 0.0 4.1 4 1 2 6 6 6 0 ATP synthase alpha/beta family, nucleotide-binding domain TPR_19 PF14559.1 EEQ31389.1 - 0.42 10.9 7.8 20 5.6 0.0 6.4 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ31390.1 - 5.3e-57 188.2 7.4 2.1e-11 43.3 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ31390.1 - 8e-54 179.5 4.4 1.6e-20 72.8 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ31390.1 - 7.4e-32 108.8 11.8 1.1e-09 37.7 0.1 4.8 1 1 4 6 6 6 6 TPR repeat TPR_7 PF13176.1 EEQ31390.1 - 1.2e-18 65.3 4.7 0.00054 19.5 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ31390.1 - 1.9e-12 47.4 2.2 0.0032 18.1 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ31390.1 - 2.7e-12 45.5 15.5 0.068 13.1 0.0 5.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ31390.1 - 6.3e-12 44.7 0.2 0.055 13.6 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ31390.1 - 6.3e-11 41.4 14.5 0.01 15.3 0.0 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EEQ31390.1 - 1.8e-07 31.1 0.3 0.048 13.8 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EEQ31390.1 - 3e-07 30.4 4.5 8.7 7.2 0.1 5.4 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ31390.1 - 1.1e-06 28.4 0.0 14 6.4 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ31390.1 - 3.4e-05 24.1 7.7 0.076 13.3 0.1 4.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ31390.1 - 0.00012 21.2 0.0 0.14 11.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 EEQ31390.1 - 0.0015 18.2 8.9 0.75 9.6 0.1 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ31390.1 - 0.031 14.0 8.9 17 5.4 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ31390.1 - 0.19 12.2 4.5 19 6.0 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat NAD_binding_10 PF13460.1 EEQ31391.1 - 3.2e-10 40.2 0.0 7.8e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEQ31391.1 - 0.00015 21.1 0.1 0.00029 20.1 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family MFS_1 PF07690.11 EEQ31392.1 - 1.2e-49 168.8 36.0 1.2e-49 168.8 25.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ31392.1 - 7.4e-09 34.6 27.4 3.9e-08 32.3 19.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EEQ31392.1 - 3.4e-06 25.5 5.7 6.2e-06 24.6 3.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EEQ31392.1 - 0.015 15.2 0.8 0.015 15.2 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) OATP PF03137.15 EEQ31392.1 - 5.1 5.0 19.7 1.5 6.8 5.2 3.5 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF202 PF02656.10 EEQ31392.1 - 8.6 6.6 9.7 6 7.1 0.0 4.7 5 2 0 5 5 5 0 Domain of unknown function (DUF202) Peptidase_M28 PF04389.12 EEQ31398.1 - 1.3e-26 93.4 0.1 3.6e-26 92.0 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EEQ31398.1 - 1.7e-05 24.4 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EEQ31398.1 - 0.0016 17.2 0.0 0.0048 15.7 0.0 1.8 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Nicastrin PF05450.10 EEQ31398.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Nicastrin fn3 PF00041.16 EEQ31398.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain PGAP1 PF07819.8 EEQ31399.1 - 9.5e-79 264.1 0.0 1.6e-78 263.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EEQ31399.1 - 3.1e-06 26.9 0.1 1.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ31399.1 - 2.1e-05 24.4 0.3 5.8e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ31399.1 - 5.7e-05 22.7 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EEQ31399.1 - 0.002 17.5 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase LCAT PF02450.10 EEQ31399.1 - 0.0091 15.0 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EEQ31399.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.6 EEQ31399.1 - 0.32 10.0 0.0 0.63 9.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF3040 PF11239.3 EEQ31399.1 - 7.6 6.6 11.3 2.8 8.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) ResIII PF04851.10 EEQ31401.1 - 1.9e-24 86.5 0.0 5.1e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ31401.1 - 7.8e-13 48.2 0.0 1.7e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ31401.1 - 6.7e-12 45.1 0.0 1.5e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 EEQ31401.1 - 3.3e-06 26.3 0.0 5.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 EEQ31401.1 - 0.04 12.7 0.0 0.063 12.0 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain UvrD-helicase PF00580.16 EEQ31401.1 - 0.18 11.0 1.9 2.2 7.4 0.0 2.6 3 1 1 4 4 4 0 UvrD/REP helicase N-terminal domain Myb_DNA-binding PF00249.26 EEQ31402.1 - 0.038 14.0 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain SWIRM PF04433.12 EEQ31403.1 - 1.7e-33 114.5 0.0 4.4e-33 113.2 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EEQ31403.1 - 1.1e-06 28.6 0.1 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ31403.1 - 1.6e-05 24.8 0.1 4.6e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EEQ31403.1 - 0.08 12.5 3.9 0.33 10.5 2.7 1.9 1 1 0 1 1 1 0 Zinc finger, ZZ type Vfa1 PF08432.5 EEQ31403.1 - 1.3 9.0 19.9 0.29 11.1 4.4 3.3 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 AAA PF00004.24 EEQ31404.1 - 1.1e-11 45.0 0.0 2.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ31404.1 - 3e-06 26.9 0.1 9.4e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ31404.1 - 9e-06 25.8 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ31404.1 - 1.6e-05 24.0 0.0 3.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EEQ31404.1 - 8.2e-05 21.4 0.0 0.00015 20.6 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EEQ31404.1 - 9.1e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ31404.1 - 9.9e-05 22.0 0.2 0.00036 20.2 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EEQ31404.1 - 0.00071 20.3 0.3 0.0031 18.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEQ31404.1 - 0.0033 16.5 0.0 0.0076 15.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EEQ31404.1 - 0.0052 16.7 0.0 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EEQ31404.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ31404.1 - 0.041 14.1 0.1 0.092 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EEQ31404.1 - 0.048 12.8 0.1 0.14 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EEQ31404.1 - 0.05 13.3 0.3 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 NTPase DUF1776 PF08643.5 EEQ31404.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) LysM PF01476.15 EEQ31407.1 - 1.1e-17 63.6 0.0 0.00012 21.8 0.0 4.2 4 0 0 4 4 4 3 LysM domain HTH_Tnp_1 PF01527.15 EEQ31407.1 - 0.0021 17.9 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 2 Transposase LRRNT_2 PF08263.7 EEQ31407.1 - 0.25 11.3 4.7 19 5.3 0.2 4.1 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain APH PF01636.18 EEQ31409.1 - 2.7e-13 50.2 0.0 6.2e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ31409.1 - 0.0018 17.8 0.1 0.0046 16.5 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF3760 PF12586.3 EEQ31410.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) ETF PF01012.16 EEQ31411.1 - 8.5e-38 129.6 0.5 1.7e-37 128.6 0.3 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EEQ31411.1 - 1.5e-34 117.4 0.1 2.9e-34 116.5 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L1 PF00687.16 EEQ31412.1 - 6.3e-51 172.8 0.1 6.3e-51 172.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family SUN PF03856.8 EEQ31413.1 - 1.8e-64 217.4 4.9 2.4e-64 217.0 3.4 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) APH PF01636.18 EEQ31415.1 - 1.4e-16 60.9 0.0 8.5e-16 58.4 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ31416.1 - 4.5e-22 78.4 0.0 1.5e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31416.1 - 5.3e-12 45.3 0.0 1.1e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EEQ31416.1 - 0.0038 17.0 0.6 0.039 13.6 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ31416.1 - 0.014 14.4 0.0 0.041 12.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_8 PF01501.15 EEQ31417.1 - 9.2e-28 97.2 0.0 1.1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EEQ31417.1 - 0.029 13.7 0.1 0.69 9.2 0.0 2.1 2 0 0 2 2 2 0 Mannosyltransferase putative Glyco_hydro_18 PF00704.23 EEQ31419.1 - 2.3e-87 293.6 0.4 2.9e-87 293.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEQ31419.1 - 1e-11 44.5 0.0 2.2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 LysM domain Pyr_redox_3 PF13738.1 EEQ31420.1 - 1.9e-18 67.3 0.6 7.1e-11 42.5 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ31420.1 - 1.9e-12 46.1 0.6 2.9e-09 35.6 0.0 3.0 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEQ31420.1 - 1.7e-06 27.2 0.0 0.00038 19.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEQ31420.1 - 2.5e-05 24.1 0.1 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ31420.1 - 2.9e-05 24.0 0.0 0.43 10.4 0.0 3.2 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ31420.1 - 8.3e-05 21.6 0.0 0.00031 19.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEQ31420.1 - 0.0025 17.5 0.0 0.03 14.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EEQ31420.1 - 0.0041 17.2 0.1 0.39 10.8 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EEQ31420.1 - 0.0079 15.3 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EEQ31420.1 - 0.23 10.2 0.6 0.34 9.7 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Upf2 PF04050.9 EEQ31421.1 - 3.4e-57 192.9 20.8 3.4e-57 192.9 14.4 2.9 3 0 0 3 3 3 1 Up-frameshift suppressor 2 MIF4G PF02854.14 EEQ31421.1 - 5.6e-48 163.1 0.0 7e-25 87.6 0.0 4.1 3 1 1 4 4 4 3 MIF4G domain TPK_catalytic PF04263.11 EEQ31422.1 - 8.3e-22 77.0 0.0 7.1e-21 74.0 0.0 2.0 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EEQ31422.1 - 4e-17 61.6 0.1 6.9e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.8 EEQ31423.1 - 1.1e-06 28.3 5.3 1.8e-06 27.7 3.6 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EEQ31423.1 - 0.026 14.6 1.5 0.05 13.7 1.1 1.5 1 0 0 1 1 1 0 GCK domain MCPVI PF02993.9 EEQ31424.1 - 0.12 12.4 2.8 0.21 11.7 1.9 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Mito_carr PF00153.22 EEQ31425.1 - 1.8e-61 203.8 4.7 2.1e-19 69.0 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein ER-remodelling PF14755.1 EEQ31425.1 - 0.0025 17.9 1.0 0.0041 17.1 0.7 1.3 1 0 0 1 1 1 1 Intracellular membrane remodeller UPF0121 PF03661.8 EEQ31426.1 - 1.7e-11 43.7 2.2 2.5e-11 43.2 1.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) MOFRL PF05161.8 EEQ31427.1 - 0.034 14.2 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 MOFRL family Septin PF00735.13 EEQ31428.1 - 1.3e-117 391.7 0.2 1.3e-117 391.7 0.2 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EEQ31428.1 - 7.1e-07 29.1 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEQ31428.1 - 6.2e-05 22.2 0.3 0.00055 19.1 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEQ31428.1 - 0.00019 20.9 1.0 0.002 17.5 0.1 2.3 2 1 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 EEQ31428.1 - 0.00048 20.4 4.9 0.022 15.0 0.0 2.7 2 1 1 3 3 3 1 ABC transporter GTP_EFTU PF00009.22 EEQ31428.1 - 0.0018 17.7 1.9 0.023 14.1 0.0 3.0 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EEQ31428.1 - 0.0019 18.2 0.2 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.17 EEQ31428.1 - 0.0037 16.6 0.0 0.016 14.6 0.0 2.1 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.1 EEQ31428.1 - 0.004 17.3 0.2 0.037 14.1 0.0 2.4 2 2 0 2 2 2 1 AAA domain AIG1 PF04548.11 EEQ31428.1 - 0.0041 16.2 0.0 0.0041 16.2 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 EEQ31428.1 - 0.0049 17.3 0.4 0.023 15.2 0.0 2.3 3 0 0 3 3 2 1 Miro-like protein AAA_29 PF13555.1 EEQ31428.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EEQ31428.1 - 0.022 14.2 1.4 0.025 14.0 0.0 1.9 2 0 0 2 2 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EEQ31428.1 - 0.023 14.5 7.9 0.48 10.2 0.0 3.7 4 1 0 4 4 4 0 Dynamin family ATP_bind_1 PF03029.12 EEQ31428.1 - 0.026 14.0 0.2 2.6 7.5 0.0 2.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EEQ31428.1 - 0.068 13.3 1.3 0.84 9.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 EEQ31428.1 - 0.073 12.6 0.5 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2937 PF11157.3 EEQ31428.1 - 0.11 11.8 3.7 0.24 10.7 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) MobB PF03205.9 EEQ31428.1 - 0.16 11.6 1.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_32 PF13654.1 EEQ31428.1 - 0.23 10.0 13.6 0.57 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain YlqD PF11068.3 EEQ31428.1 - 0.3 11.1 11.7 0.67 9.9 8.1 1.6 1 0 0 1 1 1 0 YlqD protein Phage_GPO PF05929.6 EEQ31428.1 - 0.4 9.8 8.1 0.63 9.2 5.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.10 EEQ31428.1 - 0.56 9.3 12.6 0.62 9.2 8.0 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.12 EEQ31428.1 - 1 9.1 5.9 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 APG6 PF04111.7 EEQ31428.1 - 8.1 5.3 15.6 13 4.7 10.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EEQ31428.1 - 8.9 5.1 10.6 15 4.4 7.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NAD_binding_8 PF13450.1 EEQ31429.1 - 2.3e-10 40.3 0.0 7.4e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EEQ31429.1 - 2.9e-07 29.9 0.0 0.00012 21.2 0.0 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EEQ31429.1 - 0.0022 17.7 0.0 0.092 12.5 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EEQ31429.1 - 0.014 14.3 0.0 0.05 12.4 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EEQ31429.1 - 0.046 12.3 0.0 0.096 11.2 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase RFC1 PF08519.7 EEQ31430.1 - 2.8e-56 189.5 0.3 1.9e-55 186.8 0.1 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EEQ31430.1 - 7.1e-13 48.5 0.0 2.2e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EEQ31430.1 - 2.8e-09 37.2 1.0 4.7e-09 36.5 0.1 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ31430.1 - 1.3e-05 25.3 0.0 4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ31430.1 - 3.9e-05 24.4 0.0 0.00016 22.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ31430.1 - 0.0015 18.2 0.1 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 EEQ31430.1 - 0.0015 17.2 0.0 0.0049 15.6 0.0 1.7 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EEQ31430.1 - 0.0025 16.9 0.0 0.0048 15.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EEQ31430.1 - 0.0045 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ31430.1 - 0.0076 16.2 0.0 0.033 14.1 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EEQ31430.1 - 0.0093 16.2 0.1 0.052 13.8 0.1 2.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ31430.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEQ31430.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EEQ31430.1 - 0.064 12.9 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 EEQ31430.1 - 0.098 12.3 0.0 0.33 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_L16 PF00252.13 EEQ31431.1 - 6.3e-28 97.1 0.2 8.5e-28 96.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.1 EEQ31432.1 - 1.4e-11 44.3 0.1 2.5e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EEQ31432.1 - 2.7e-10 40.0 0.5 2.6e-08 33.7 0.0 2.8 2 1 1 3 3 3 1 Replication factor C C-terminal domain AAA PF00004.24 EEQ31432.1 - 7.1e-07 29.4 0.1 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ31432.1 - 1.1e-05 25.6 0.5 7.3e-05 22.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ31432.1 - 0.00077 19.4 2.0 0.02 14.9 0.6 2.7 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EEQ31432.1 - 0.011 16.0 0.1 0.021 15.1 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 EEQ31432.1 - 0.013 15.5 0.4 0.35 10.9 0.3 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 EEQ31432.1 - 0.014 14.8 0.1 0.89 8.9 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EEQ31432.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EEQ31432.1 - 0.033 12.9 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain T4SS-DNA_transf PF02534.9 EEQ31432.1 - 0.063 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Arch_ATPase PF01637.13 EEQ31432.1 - 0.066 12.9 0.2 0.22 11.1 0.1 1.8 1 1 0 1 1 1 0 Archaeal ATPase Methyltransf_31 PF13847.1 EEQ31432.1 - 0.082 12.4 0.1 0.72 9.4 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain TK PF00265.13 EEQ31432.1 - 0.11 11.9 0.7 0.53 9.8 0.5 1.9 1 1 0 1 1 1 0 Thymidine kinase AAA_24 PF13479.1 EEQ31432.1 - 0.33 10.4 1.5 1.6 8.2 1.0 2.0 1 1 0 1 1 1 0 AAA domain CtaG_Cox11 PF04442.9 EEQ31433.1 - 4.7e-60 201.7 0.1 6.1e-60 201.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Bd3614_N PF14442.1 EEQ31433.1 - 0.012 15.6 0.1 2.3 8.2 0.1 2.2 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal BRCA2 PF00634.13 EEQ31433.1 - 0.11 11.7 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 BRCA2 repeat Polysacc_deac_1 PF01522.16 EEQ31434.1 - 3.4e-30 104.2 0.0 5e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase PT PF04886.7 EEQ31434.1 - 0.84 9.0 39.7 47 3.4 18.4 2.7 1 1 1 2 2 2 0 PT repeat Pkinase PF00069.20 EEQ31436.1 - 4.3e-10 39.1 0.0 9e-10 38.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31436.1 - 0.013 14.6 0.0 0.025 13.6 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase Peptidase_M35 PF02102.10 EEQ31438.1 - 2e-107 359.0 6.0 2.3e-107 358.7 4.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.1 EEQ31438.1 - 3.8e-05 23.2 0.6 8.7e-05 22.0 0.4 1.5 1 1 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 EEQ31438.1 - 0.00031 21.2 0.2 0.00073 20.0 0.0 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase IceA2 PF05862.6 EEQ31438.1 - 0.03 14.0 1.1 0.076 12.7 0.8 1.7 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein Semialdhyde_dhC PF02774.13 EEQ31439.1 - 2.2e-37 128.7 0.0 3e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EEQ31439.1 - 2.5e-29 102.0 0.0 7.5e-29 100.4 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EEQ31439.1 - 0.00072 20.0 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EEQ31439.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cation_ATPase_C PF00689.16 EEQ31440.1 - 0.036 13.5 0.7 0.066 12.7 0.1 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus HLH PF00010.21 EEQ31441.1 - 7.8e-08 31.8 0.0 3e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Gon7 PF08738.5 EEQ31441.1 - 0.68 9.9 5.5 8.1 6.4 1.9 2.7 2 0 0 2 2 2 0 Gon7 family Ser_hydrolase PF06821.8 EEQ31443.1 - 0.055 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase CENP-Q PF13094.1 EEQ31445.1 - 3.4e-53 179.9 2.5 5.9e-53 179.1 1.8 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin PF00261.15 EEQ31445.1 - 0.16 10.9 15.0 0.021 13.9 6.9 2.0 2 1 1 3 3 3 0 Tropomyosin Cep57_CLD_2 PF14197.1 EEQ31445.1 - 0.19 11.6 11.2 16 5.5 0.0 3.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 BRE1 PF08647.6 EEQ31445.1 - 0.27 11.2 9.8 0.2 11.6 5.3 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_TATA_bd PF12325.3 EEQ31445.1 - 0.29 10.8 10.7 0.062 13.0 4.3 2.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 EEQ31445.1 - 0.3 10.1 5.1 0.43 9.5 3.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4337 PF14235.1 EEQ31445.1 - 0.65 9.8 4.6 1.4 8.7 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) IncA PF04156.9 EEQ31445.1 - 0.69 9.4 7.2 1.4 8.4 5.0 1.5 1 0 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 EEQ31445.1 - 1.1 9.0 15.8 1.3 8.9 7.9 2.4 2 0 0 2 2 2 0 Tropomyosin like DUF904 PF06005.7 EEQ31445.1 - 9.8 6.5 13.2 1.4e+02 2.8 8.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Zn_clus PF00172.13 EEQ31446.1 - 0.012 15.4 3.8 0.024 14.5 2.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_2 PF12680.2 EEQ31446.1 - 0.013 15.9 0.0 0.036 14.4 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like domain SPO22 PF08631.5 EEQ31447.1 - 4.7e-18 65.2 0.2 7.4e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like DUF4351 PF14261.1 EEQ31448.1 - 0.08 12.8 0.1 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) WD40 PF00400.27 EEQ31449.1 - 7.5e-24 82.6 13.8 8.7e-06 25.4 0.0 9.0 9 0 0 9 9 9 7 WD domain, G-beta repeat FTA2 PF13095.1 EEQ31450.1 - 5.1e-63 212.4 0.0 6.7e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Nucleoplasmin PF03066.10 EEQ31451.1 - 0.024 14.1 5.1 0.041 13.4 3.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Radial_spoke PF04712.7 EEQ31451.1 - 0.053 12.2 0.6 0.083 11.6 0.4 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein NOA36 PF06524.7 EEQ31451.1 - 0.32 10.2 2.9 0.52 9.5 2.0 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.1 EEQ31451.1 - 0.67 10.1 6.8 1.9 8.6 4.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 EEQ31451.1 - 0.81 9.9 12.4 1.6 9.0 8.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EEQ31451.1 - 0.92 9.0 5.6 1.6 8.2 3.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4366 PF14283.1 EEQ31451.1 - 1.1 8.6 5.0 1.8 7.9 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PBP1_TM PF14812.1 EEQ31451.1 - 1.3 9.3 7.5 3 8.2 5.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 EEQ31451.1 - 1.4 8.5 3.2 4.4 6.9 2.2 1.8 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.6 EEQ31451.1 - 2.1 6.9 3.4 3.7 6.1 2.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_60s PF00428.14 EEQ31451.1 - 2.2 8.7 8.5 0.35 11.2 3.0 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nop14 PF04147.7 EEQ31451.1 - 6.3 4.5 7.6 9.2 4.0 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 EEQ31452.1 - 7e-37 126.9 20.5 7e-37 126.9 14.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ31452.1 - 2.1e-08 33.2 8.7 2.1e-08 33.2 6.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Sugar_tr PF00083.19 EEQ31453.1 - 4.1e-81 272.8 27.1 4.6e-81 272.6 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ31453.1 - 6.1e-24 84.3 23.3 6.1e-24 84.3 16.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily GCN5L1 PF06320.8 EEQ31454.1 - 2.3e-10 40.3 3.3 2.9e-10 40.0 2.3 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Nsp1_C PF05064.8 EEQ31454.1 - 0.015 14.9 4.6 0.023 14.3 3.1 1.4 1 1 0 1 1 1 0 Nsp1-like C-terminal region Paramyxo_C PF01692.13 EEQ31454.1 - 0.018 14.6 0.6 0.021 14.4 0.5 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c CagE_TrbE_VirB PF03135.9 EEQ31454.1 - 0.027 14.2 0.1 0.028 14.1 0.1 1.1 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system SCP-1 PF05483.7 EEQ31454.1 - 0.053 11.3 5.6 0.063 11.0 3.9 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) DivIC PF04977.10 EEQ31454.1 - 0.057 12.9 4.3 0.11 12.0 3.0 1.4 1 0 0 1 1 1 0 Septum formation initiator PilJ PF13675.1 EEQ31454.1 - 0.068 13.4 2.1 0.1 12.9 1.5 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Gasdermin PF04598.7 EEQ31454.1 - 0.071 11.8 2.5 0.077 11.7 1.8 1.1 1 0 0 1 1 1 0 Gasdermin family zf-C4H2 PF10146.4 EEQ31454.1 - 0.1 12.6 0.6 0.12 12.4 0.4 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF3552 PF12072.3 EEQ31454.1 - 0.1 11.7 6.6 0.053 12.7 3.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1492 PF07374.6 EEQ31454.1 - 0.12 12.4 0.4 0.2 11.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Prominin PF05478.6 EEQ31454.1 - 0.19 9.2 1.1 0.2 9.1 0.7 1.1 1 0 0 1 1 1 0 Prominin DUF848 PF05852.6 EEQ31454.1 - 0.35 10.7 6.0 0.42 10.4 3.6 1.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) APG6 PF04111.7 EEQ31454.1 - 1.2 8.0 6.6 1.3 7.9 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SPT2 PF08243.6 EEQ31454.1 - 1.8 8.8 8.5 0.035 14.4 1.5 1.5 2 0 0 2 2 1 0 SPT2 chromatin protein Syntaxin-6_N PF09177.6 EEQ31454.1 - 2.7 8.4 6.5 39 4.7 4.5 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Rabaptin PF03528.10 EEQ31454.1 - 9.4 6.2 10.6 4.5 7.2 1.3 2.2 1 1 1 2 2 2 0 Rabaptin DNA_mis_repair PF01119.14 EEQ31455.1 - 1.1e-20 73.2 0.1 3.4e-19 68.4 0.0 3.0 4 0 0 4 4 4 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EEQ31455.1 - 1e-18 67.3 2.3 2e-15 56.6 1.3 3.0 2 1 0 2 2 2 2 MutL C terminal dimerisation domain NOA36 PF06524.7 EEQ31455.1 - 2.4 7.3 7.9 5.4 6.1 5.5 1.5 1 0 0 1 1 1 0 NOA36 protein Serinc PF03348.10 EEQ31456.1 - 4.7e-175 582.4 11.9 5.4e-175 582.2 8.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ATG27 PF09451.5 EEQ31456.1 - 0.98 8.5 3.1 0.49 9.5 0.1 1.9 2 1 0 2 2 2 0 Autophagy-related protein 27 ABC2_membrane_3 PF12698.2 EEQ31456.1 - 4.4 6.2 26.7 4.9 6.0 9.0 3.6 1 1 2 3 3 3 0 ABC-2 family transporter protein Nodulin-like PF06813.8 EEQ31457.1 - 2.2e-20 73.0 3.8 4.6e-20 71.9 2.6 1.5 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 EEQ31457.1 - 1.2e-09 37.4 32.0 4.3e-07 28.9 22.2 3.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ31457.1 - 0.2 10.1 17.2 0.025 13.1 7.2 2.6 2 1 1 3 3 3 0 Sugar (and other) transporter BTP PF05232.7 EEQ31457.1 - 4.1 7.2 7.8 0.59 9.9 0.1 3.1 3 0 0 3 3 3 0 Bacterial Transmembrane Pair family DivIVA PF05103.8 EEQ31458.1 - 0.00093 19.2 1.9 0.00093 19.2 1.3 1.8 2 0 0 2 2 2 1 DivIVA protein DUF3461 PF11944.3 EEQ31458.1 - 0.037 13.8 0.6 0.059 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) IncA PF04156.9 EEQ31458.1 - 0.1 12.1 4.9 0.16 11.5 3.4 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EEQ31458.1 - 0.24 10.3 4.9 0.39 9.7 3.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4164 PF13747.1 EEQ31458.1 - 0.26 11.4 5.3 0.53 10.4 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF904 PF06005.7 EEQ31458.1 - 0.28 11.5 5.9 0.48 10.7 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) SlyX PF04102.7 EEQ31458.1 - 0.48 10.8 3.9 1.1 9.6 2.7 1.6 1 0 0 1 1 1 0 SlyX Pox_A_type_inc PF04508.7 EEQ31458.1 - 0.59 10.0 5.2 0.94 9.4 1.5 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PI3_PI4_kinase PF00454.22 EEQ31459.1 - 2.2e-39 135.3 0.0 3.2e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.18 EEQ31460.1 - 4e-67 226.1 0.1 5.8e-67 225.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ31460.1 - 1.1e-08 34.7 0.0 2.9e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ31460.1 - 5e-07 29.3 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HIRAN PF08797.6 EEQ31460.1 - 0.035 14.0 0.0 0.093 12.6 0.0 1.9 1 0 0 1 1 1 0 HIRAN domain zf-RING_5 PF14634.1 EEQ31460.1 - 0.53 10.0 1.5 0.96 9.2 1.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PyrI_C PF02748.10 EEQ31460.1 - 1.9 8.0 4.4 2.3 7.7 0.0 2.6 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Med21 PF11221.3 EEQ31461.1 - 1.3e-48 164.6 18.8 5.6e-48 162.5 13.0 1.7 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 EEQ31461.1 - 0.005 16.5 1.5 0.005 16.5 1.1 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Spore_III_AB PF09548.5 EEQ31461.1 - 0.058 13.1 1.3 0.064 13.0 0.2 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PAT1 PF09770.4 EEQ31461.1 - 0.52 8.4 16.5 0.58 8.3 11.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2034 PF10356.4 EEQ31462.1 - 3e-37 127.5 0.0 9.7e-21 73.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EEQ31462.1 - 6.2e-08 32.4 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease DUF3431 PF11913.3 EEQ31463.1 - 2.3e-67 226.7 0.0 2.6e-64 216.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Spc24 PF08286.6 EEQ31464.1 - 5.8e-41 138.8 3.1 1.3e-39 134.5 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 EEQ31464.1 - 0.0024 17.8 2.8 0.0061 16.5 0.3 2.1 1 1 1 2 2 2 1 Lantibiotic streptin immunity protein APG6 PF04111.7 EEQ31464.1 - 0.0059 15.7 5.5 0.0074 15.3 3.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 EEQ31464.1 - 0.009 13.9 3.5 0.01 13.7 2.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family WXG100 PF06013.7 EEQ31464.1 - 0.011 15.7 1.5 0.17 11.9 0.0 2.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG MAP65_ASE1 PF03999.7 EEQ31464.1 - 0.019 13.6 4.7 0.025 13.2 3.3 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) FlaC_arch PF05377.6 EEQ31464.1 - 0.052 13.4 2.4 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.15 EEQ31464.1 - 0.11 12.2 7.5 0.59 9.9 0.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF342 PF03961.8 EEQ31464.1 - 0.12 10.8 2.1 0.14 10.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Viral_P18 PF04521.8 EEQ31464.1 - 0.13 11.7 6.9 0.36 10.2 0.6 2.4 1 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF972 PF06156.8 EEQ31464.1 - 0.33 11.3 5.8 2.3 8.5 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Syntaxin PF00804.20 EEQ31464.1 - 0.35 11.0 10.1 0.3 11.2 4.1 2.3 1 1 1 2 2 2 0 Syntaxin DUF4613 PF15390.1 EEQ31464.1 - 0.37 8.9 3.8 0.45 8.6 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF2408 PF10303.4 EEQ31464.1 - 0.5 10.4 4.3 1.5 8.9 3.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TMF_DNA_bd PF12329.3 EEQ31464.1 - 0.54 10.1 10.9 0.3 10.8 2.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding YjcZ PF13990.1 EEQ31464.1 - 0.63 9.1 4.1 0.35 9.9 0.5 1.8 1 1 1 2 2 2 0 YjcZ-like protein DUF3774 PF12609.3 EEQ31464.1 - 0.68 10.8 2.6 0.61 10.9 0.6 1.7 1 1 1 2 2 2 0 Wound-induced protein Occludin_ELL PF07303.8 EEQ31464.1 - 0.75 10.5 3.6 8.2 7.2 1.7 2.3 1 1 1 2 2 2 0 Occludin homology domain GAS PF13851.1 EEQ31464.1 - 1 8.4 8.0 1.1 8.3 0.8 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DASH_Dad3 PF08656.5 EEQ31464.1 - 1.1 9.0 5.3 2 8.1 0.8 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad3 TBPIP PF07106.8 EEQ31464.1 - 1.7 8.1 7.3 1.1 8.7 1.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 EEQ31464.1 - 1.9 8.9 9.5 7.8 7.0 1.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ribosomal_L29 PF00831.18 EEQ31464.1 - 3.9 7.2 8.0 10 5.8 0.6 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein Mnd1 PF03962.10 EEQ31464.1 - 4.1 7.0 7.4 4.5 6.8 4.2 1.6 1 1 1 2 2 2 0 Mnd1 family PCRF PF03462.13 EEQ31464.1 - 4.3 7.0 5.7 5.2 6.8 0.3 2.2 2 0 0 2 2 2 0 PCRF domain Cep57_MT_bd PF06657.8 EEQ31464.1 - 5.3 7.0 9.0 11 6.0 0.5 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Fis1_TPR_C PF14853.1 EEQ31465.1 - 2.1e-25 88.3 0.4 3.4e-25 87.6 0.3 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EEQ31465.1 - 6.1e-17 60.6 0.0 9.5e-17 60.0 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EEQ31465.1 - 0.00079 19.1 1.6 0.002 17.8 1.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ31465.1 - 0.02 15.5 0.1 0.046 14.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ31465.1 - 0.096 12.3 2.3 0.22 11.1 1.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 EEQ31466.1 - 3.4e-15 55.5 21.0 9.5e-15 54.1 5.9 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ31466.1 - 1.3e-10 40.7 10.6 7.4e-09 35.1 2.7 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ31466.1 - 1.2e-07 31.7 3.9 1.2e-07 31.7 2.7 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEQ31466.1 - 2.9e-07 30.0 17.3 6.3e-07 28.9 5.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ31466.1 - 3.4e-07 30.1 16.6 4.2e-07 29.8 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ31466.1 - 6.5e-07 28.9 14.8 1.2e-06 28.0 3.9 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_3 PF14369.1 EEQ31466.1 - 9.6e-07 28.7 11.4 0.0001 22.2 4.2 2.6 2 0 0 2 2 2 2 zinc-finger HypA PF01155.14 EEQ31466.1 - 0.00021 20.9 0.7 0.00021 20.9 0.5 2.2 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-Apc11 PF12861.2 EEQ31466.1 - 0.00046 19.9 2.8 0.00046 19.9 2.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 EEQ31466.1 - 0.0089 15.8 0.7 0.0089 15.8 0.5 2.7 2 1 1 3 3 3 1 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 EEQ31466.1 - 0.2 11.5 13.2 2.3 8.1 0.7 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.2 EEQ31466.1 - 0.32 10.8 9.0 0.17 11.7 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 EEQ31466.1 - 0.39 10.3 14.0 0.21 11.1 2.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.1 EEQ31466.1 - 0.82 8.9 4.7 46 3.3 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain FANCL_C PF11793.3 EEQ31466.1 - 4.4 7.3 10.5 2.5 8.1 4.6 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain UPF0547 PF10571.4 EEQ31466.1 - 9.6 6.0 9.7 15 5.3 0.2 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Aminotran_5 PF00266.14 EEQ31467.1 - 3.7e-22 78.5 0.0 4.8e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EEQ31467.1 - 3.4e-05 22.9 0.0 4.7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEQ31467.1 - 0.032 12.5 0.0 0.046 11.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_trans_1_2 PF13524.1 EEQ31469.1 - 0.099 12.9 0.8 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 APH PF01636.18 EEQ31471.1 - 2.5e-16 60.1 0.0 4.9e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ31471.1 - 6.4e-06 25.3 0.0 0.55 9.2 0.0 3.3 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEQ31471.1 - 0.017 14.4 0.0 0.79 9.0 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF1679 PF07914.6 EEQ31471.1 - 0.096 11.3 0.0 1 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) ADH_zinc_N PF00107.21 EEQ31472.1 - 1.6e-22 79.4 0.5 2.4e-22 78.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ31472.1 - 1.2e-07 32.7 0.2 3.7e-07 31.0 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ31472.1 - 0.0014 18.3 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EEQ31472.1 - 0.0091 16.0 0.6 0.02 14.8 0.2 1.9 2 1 0 2 2 2 1 NADH(P)-binding GAD PF02938.9 EEQ31472.1 - 0.03 14.4 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 GAD domain Sars6 PF12133.3 EEQ31474.1 - 0.039 13.6 0.1 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus Trp_syntA PF00290.15 EEQ31476.1 - 1e-90 302.7 0.0 1.9e-90 301.9 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EEQ31476.1 - 1.2e-43 149.4 1.1 2.2e-43 148.6 0.7 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Adeno_E3_CR2 PF02439.10 EEQ31477.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1517 PF07466.6 EEQ31477.1 - 0.14 11.0 0.8 0.22 10.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) EphA2_TM PF14575.1 EEQ31477.1 - 0.16 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ATP-synt_ab PF00006.20 EEQ31478.1 - 1.5e-61 207.6 0.0 2e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEQ31478.1 - 1.9e-17 63.7 0.0 3.6e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEQ31478.1 - 8.5e-11 41.9 0.8 1.8e-10 40.8 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEQ31478.1 - 0.00012 21.8 0.3 0.00025 20.8 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Peptidase_S10 PF00450.17 EEQ31479.1 - 1.8e-68 231.6 0.0 5.5e-68 230.0 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEQ31479.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family FYVE PF01363.16 EEQ31480.1 - 0.1 12.5 0.8 0.13 12.1 0.6 1.5 1 1 0 1 1 1 0 FYVE zinc finger DUF2180 PF09947.4 EEQ31480.1 - 0.2 11.4 3.0 0.23 11.2 1.0 1.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) IBR PF01485.16 EEQ31482.1 - 3.9e-07 29.8 5.3 3.9e-07 29.8 3.6 3.6 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 EEQ31482.1 - 0.001 18.7 2.7 0.001 18.7 1.9 3.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEQ31482.1 - 0.0012 18.5 1.6 0.0037 16.9 1.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EEQ31482.1 - 0.0046 16.9 5.9 0.0046 16.9 4.1 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Dynamin_M PF01031.15 EEQ31483.1 - 2.9e-18 65.6 0.2 4.2e-16 58.5 0.0 3.2 1 1 2 3 3 3 2 Dynamin central region Dynamin_N PF00350.18 EEQ31483.1 - 3.8e-15 56.1 0.1 8.7e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EEQ31483.1 - 0.032 14.2 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Usp PF00582.21 EEQ31486.1 - 1.7e-07 31.4 2.0 0.0032 17.6 0.0 2.9 3 0 0 3 3 3 2 Universal stress protein family DnaJ PF00226.26 EEQ31487.1 - 6.4e-24 83.4 3.3 9.3e-24 82.9 1.6 1.9 2 0 0 2 2 2 1 DnaJ domain DUF4463 PF14703.1 EEQ31487.1 - 9.7 6.7 10.4 1.2 9.6 1.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4463) HAD_2 PF13419.1 EEQ31488.1 - 1.4e-22 80.7 0.0 1.7e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ31488.1 - 1.9e-11 44.8 0.3 9.8e-10 39.1 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ31488.1 - 3e-11 42.8 0.0 8.9e-11 41.3 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EEQ31488.1 - 3.7e-08 33.7 0.0 5.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EEQ31488.1 - 7.3e-05 22.5 0.0 0.024 14.5 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ31488.1 - 0.042 13.4 0.1 1.6 8.2 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PNK3P PF08645.6 EEQ31488.1 - 0.11 11.9 0.2 17 4.8 0.0 2.7 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Pterin_4a PF01329.14 EEQ31489.1 - 7.6e-22 76.8 0.1 8e-20 70.4 0.1 2.4 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase UPRTase PF14681.1 EEQ31489.1 - 3.6e-16 58.9 0.0 5.4e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEQ31489.1 - 1.8e-05 24.4 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MFS_1 PF07690.11 EEQ31490.1 - 2.5e-38 131.6 72.4 8.2e-28 97.1 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ31490.1 - 1.4e-07 30.4 35.3 0.00015 20.5 11.7 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter Anoctamin PF04547.7 EEQ31490.1 - 0.26 9.8 3.9 3.4 6.2 0.5 2.6 2 0 0 2 2 2 0 Calcium-activated chloride channel Pkinase PF00069.20 EEQ31495.1 - 9.6e-60 201.9 0.0 3e-59 200.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31495.1 - 3.7e-28 98.3 0.0 2.5e-27 95.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ31495.1 - 0.056 12.2 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.2 EEQ31497.1 - 1.3e-20 73.1 3.9 2.6e-20 72.2 2.7 1.5 1 0 0 1 1 1 1 Stc1 domain zf-met PF12874.2 EEQ31497.1 - 6.5 7.1 7.9 24 5.3 1.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type APH PF01636.18 EEQ31498.1 - 1.9e-13 50.6 0.0 1.4e-12 47.9 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family TPR_12 PF13424.1 EEQ31500.1 - 1.2e-18 66.8 2.0 3.7e-07 29.9 0.1 4.2 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ31500.1 - 6e-05 22.8 1.4 0.48 10.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ31500.1 - 0.00016 21.9 0.1 0.38 11.1 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ31500.1 - 0.0002 20.9 0.4 9.8 6.3 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ31500.1 - 0.0015 18.0 0.8 3 7.5 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ31500.1 - 0.0015 18.1 0.3 1.1 9.2 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ31500.1 - 0.0019 18.2 2.8 0.2 11.8 0.6 3.1 1 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EEQ31500.1 - 0.0051 16.7 2.7 15 5.7 0.0 3.7 3 0 0 3 3 3 0 PPR repeat TPR_11 PF13414.1 EEQ31500.1 - 0.006 16.1 0.9 1.6 8.4 0.1 3.5 2 1 2 4 4 4 1 TPR repeat TPR_14 PF13428.1 EEQ31500.1 - 0.054 14.1 0.1 1.1e+02 3.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.1 EEQ31500.1 - 0.071 13.4 1.2 2.7 8.5 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Abhydrolase_6 PF12697.2 EEQ31504.1 - 2e-14 54.0 0.2 3.1e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ31504.1 - 0.065 12.7 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ31504.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Golgin_A5 PF09787.4 EEQ31507.1 - 2.3 6.6 3.9 3.9 5.8 2.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Zip PF02535.17 EEQ31507.1 - 5.4 5.9 10.3 10 5.0 7.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Stn1 PF10451.4 EEQ31508.1 - 3.8e-14 52.1 0.6 2.1e-12 46.4 0.4 2.1 1 1 0 1 1 1 1 Telomere regulation protein Stn1 DUF1757 PF08560.5 EEQ31508.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1757) DUF2175 PF09943.4 EEQ31508.1 - 0.093 12.7 0.2 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF2956 PF11169.3 EEQ31508.1 - 0.9 9.5 6.2 1.6 8.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Toxin_57 PF15535.1 EEQ31509.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 57 dCMP_cyt_deam_1 PF00383.17 EEQ31510.1 - 8.9e-10 38.1 0.0 8.1e-09 35.0 0.0 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EEQ31510.1 - 1.6e-06 27.8 0.2 3e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Metallophos PF00149.23 EEQ31511.1 - 0.00024 20.5 1.4 0.0022 17.4 1.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ31511.1 - 0.0025 17.6 0.0 0.0064 16.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1814 PF08843.6 EEQ31512.1 - 4.4e-07 29.9 0.0 5.8e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) NTP_transf_2 PF01909.18 EEQ31512.1 - 0.012 15.8 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase domain RNase_PH PF01138.16 EEQ31514.1 - 4.8e-13 49.5 0.0 1.3e-12 48.1 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Orbi_NS3 PF01616.11 EEQ31515.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Orbivirus NS3 Baculo_PEP_C PF04513.7 EEQ31518.1 - 0.23 11.2 6.5 0.68 9.7 0.5 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_A_bac PF01000.21 EEQ31519.1 - 8.2e-31 106.4 0.0 1.3e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEQ31519.1 - 1.4e-11 43.3 0.0 2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.20 EEQ31520.1 - 3.1e-19 69.1 0.0 6e-19 68.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain IER PF05760.7 EEQ31521.1 - 0.32 10.8 3.8 0.31 10.9 1.7 1.4 1 1 0 1 1 1 0 Immediate early response protein (IER) Pkinase PF00069.20 EEQ31522.1 - 8.1e-30 103.8 0.0 1.1e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31522.1 - 1.6e-14 53.6 0.0 4e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ31522.1 - 0.027 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family NUDIX PF00293.23 EEQ31523.1 - 1.1e-18 67.1 0.3 1.3e-18 66.9 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain TraI_2 PF07514.6 EEQ31523.1 - 0.12 11.1 1.4 0.25 10.0 1.0 1.5 1 1 0 1 1 1 0 Putative helicase ATE_C PF04377.10 EEQ31524.1 - 2.7e-39 134.1 1.8 4.7e-39 133.3 1.2 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EEQ31524.1 - 1.3e-21 76.1 5.9 2.6e-21 75.2 4.1 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Transp_cyt_pur PF02133.10 EEQ31525.1 - 2.8e-30 105.2 36.4 3.1e-29 101.8 25.2 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin WD40 PF00400.27 EEQ31526.1 - 1e-14 53.7 5.4 2.9e-05 23.7 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EEQ31526.1 - 7.5e-13 48.4 0.2 3.4e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EEQ31526.1 - 0.00032 20.5 0.3 0.0013 18.5 0.2 1.8 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 EEQ31526.1 - 0.022 14.5 1.7 0.2 11.4 0.0 3.0 3 0 0 3 3 3 0 Prp18 domain RRM_1 PF00076.17 EEQ31527.1 - 1.5e-16 59.7 0.0 2.1e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31527.1 - 1.5e-10 40.9 0.0 2.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ31527.1 - 5.4e-09 35.7 0.0 7.9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ31527.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif COX6B PF02297.12 EEQ31528.1 - 3e-19 68.8 7.3 3.5e-19 68.5 5.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EEQ31528.1 - 0.0043 16.4 1.2 0.0078 15.5 0.8 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 EEQ31528.1 - 0.019 14.4 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UCR_hinge PF02320.11 EEQ31528.1 - 0.079 12.9 0.2 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Mito_carr PF00153.22 EEQ31529.1 - 3.7e-55 183.6 0.2 1.1e-18 66.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.15 EEQ31530.1 - 2.9e-47 160.9 0.0 4.4e-26 91.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EEQ31530.1 - 6e-27 93.6 0.0 1.6e-26 92.2 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.14 EEQ31531.1 - 3e-44 150.4 3.6 4.4e-44 149.9 2.5 1.2 1 0 0 1 1 1 1 GrpE PEARLI-4 PF05278.7 EEQ31531.1 - 0.027 13.8 1.3 0.046 13.0 0.9 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) TPD52 PF04201.10 EEQ31531.1 - 0.036 13.8 2.4 0.05 13.3 1.7 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Focal_AT PF03623.8 EEQ31531.1 - 0.057 12.8 0.1 0.14 11.6 0.1 1.7 1 1 0 1 1 1 0 Focal adhesion targeting region Phage_GP20 PF06810.6 EEQ31531.1 - 0.18 11.2 6.9 0.48 9.8 4.8 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 EEQ31531.1 - 0.19 11.3 3.2 0.29 10.7 2.2 1.3 1 0 0 1 1 1 0 IncA protein Erythro-docking PF09277.6 EEQ31531.1 - 0.21 11.3 0.2 0.21 11.3 0.1 2.4 3 0 0 3 3 3 0 Erythronolide synthase, docking Bap31 PF05529.7 EEQ31531.1 - 1.2 8.5 5.4 0.62 9.4 2.3 1.6 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EEQ31531.1 - 1.6 8.6 7.3 0.28 11.0 1.9 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Uds1 PF15456.1 EEQ31532.1 - 3.6e-31 107.7 6.7 4e-31 107.5 2.9 2.1 2 0 0 2 2 2 1 Up-regulated During Septation Spc7 PF08317.6 EEQ31532.1 - 0.034 12.8 0.3 0.051 12.2 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EEQ31532.1 - 0.21 11.5 1.7 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Calcipressin PF04847.7 EEQ31536.1 - 1.1e-32 113.1 0.5 2.7e-32 111.8 0.3 1.5 1 1 0 1 1 1 1 Calcipressin Pex14_N PF04695.8 EEQ31537.1 - 2.3e-31 108.6 0.9 2.3e-31 108.6 0.6 2.7 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sigma70_ECF PF07638.6 EEQ31537.1 - 0.1 12.2 0.1 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 ECF sigma factor PAPA-1 PF04795.7 EEQ31538.1 - 3.3e-24 85.3 6.9 3.3e-24 85.3 4.8 2.6 3 1 0 3 3 3 1 PAPA-1-like conserved region Mus7 PF09462.5 EEQ31539.1 - 1.6e-150 502.8 0.8 3.3e-150 501.8 0.5 1.5 1 0 0 1 1 1 1 Mus7/MMS22 family DUF4050 PF13259.1 EEQ31540.1 - 1e-37 128.7 0.1 1.8e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) CorA PF01544.13 EEQ31541.1 - 1.4e-10 40.6 3.0 3e-09 36.3 0.6 2.2 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Ank_2 PF12796.2 EEQ31542.1 - 1.7e-32 111.5 0.0 3.4e-20 72.1 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ31542.1 - 1.3e-27 94.1 0.5 3.6e-10 39.1 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 EEQ31542.1 - 4.6e-23 79.0 0.1 8.7e-07 28.5 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EEQ31542.1 - 6.3e-22 77.5 0.4 3.5e-13 49.6 0.1 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ31542.1 - 2.4e-19 68.8 2.7 3.7e-08 33.3 0.1 5.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EEQ31542.1 - 1.6e-14 53.5 0.0 2.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EEQ31542.1 - 3.9e-09 36.3 0.0 1.1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EEQ31542.1 - 0.0017 18.4 0.0 0.011 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEQ31542.1 - 0.041 14.0 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 EEQ31542.1 - 0.042 12.8 0.0 0.099 11.6 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 EEQ31542.1 - 0.078 12.7 0.0 0.28 10.9 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain DUF454 PF04304.8 EEQ31542.1 - 1.9 8.5 8.0 0.53 10.3 0.1 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF454) HlyIII PF03006.15 EEQ31543.1 - 9e-38 129.8 14.2 1.1e-37 129.5 9.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related APH PF01636.18 EEQ31544.1 - 3.7e-14 53.0 0.0 1.1e-13 51.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 EEQ31547.1 - 0.00011 22.0 0.0 0.00048 19.9 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ31547.1 - 0.1 11.2 0.0 0.25 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) PYC_OADA PF02436.13 EEQ31547.1 - 0.16 11.4 0.1 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain Pkinase PF00069.20 EEQ31548.1 - 1e-19 70.7 0.0 4.8e-19 68.5 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31548.1 - 2.8e-11 42.9 0.0 9.9e-11 41.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ31548.1 - 0.0058 15.4 0.2 0.1 11.3 0.1 2.2 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase AAA PF00004.24 EEQ31549.1 - 6e-39 133.2 0.0 7.4e-38 129.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ31549.1 - 4.5e-05 23.6 0.1 0.0017 18.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ31549.1 - 0.00012 22.1 0.0 0.013 15.4 0.0 3.0 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EEQ31549.1 - 0.00013 21.0 0.0 0.0003 19.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEQ31549.1 - 0.00026 20.9 0.0 0.0044 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EEQ31549.1 - 0.00034 19.4 0.0 0.00072 18.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EEQ31549.1 - 0.00061 20.6 0.1 0.0034 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ31549.1 - 0.0007 19.3 0.0 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EEQ31549.1 - 0.0031 17.2 0.2 0.0096 15.6 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EEQ31549.1 - 0.0036 16.4 0.1 0.0079 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EEQ31549.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ31549.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EEQ31549.1 - 0.0071 16.3 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ31549.1 - 0.016 14.3 0.5 0.38 9.8 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.17 EEQ31549.1 - 0.019 15.1 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EEQ31549.1 - 0.031 13.8 0.1 0.083 12.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEQ31549.1 - 0.049 13.0 0.2 8.3 5.7 0.0 2.5 1 1 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EEQ31549.1 - 0.064 12.6 0.2 0.3 10.4 0.1 2.0 1 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EEQ31549.1 - 0.083 12.5 0.1 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 EEQ31549.1 - 0.096 12.1 0.1 2.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.11 EEQ31549.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase SHQ1 PF04925.10 EEQ31549.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 SHQ1 protein AAA_18 PF13238.1 EEQ31549.1 - 0.28 11.4 0.1 0.28 11.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain LIM_bind PF01803.11 EEQ31550.1 - 1.4e-55 188.0 0.0 1.4e-55 188.0 0.0 3.8 3 1 0 3 3 3 1 LIM-domain binding protein cobW PF02492.14 EEQ31551.1 - 4e-34 117.5 0.0 4.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EEQ31551.1 - 3.2e-06 26.1 0.0 0.02 13.7 0.1 2.1 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EEQ31551.1 - 0.0067 16.3 0.0 0.017 15.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EEQ31551.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EEQ31551.1 - 0.023 15.0 0.0 0.037 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ31551.1 - 0.028 15.2 0.0 0.051 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEQ31551.1 - 0.034 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 EEQ31551.1 - 0.038 13.4 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.18 EEQ31551.1 - 0.053 12.9 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 EEQ31551.1 - 0.092 12.1 0.0 2.3 7.5 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_21 PF13304.1 EEQ31551.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEQ31551.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) BING4CT PF08149.6 EEQ31552.1 - 5e-41 138.0 0.0 8.9e-38 127.6 0.0 2.9 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EEQ31552.1 - 1.5e-05 24.6 0.0 0.027 14.3 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF4427 PF14468.1 EEQ31552.1 - 0.023 14.4 3.0 0.061 13.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4427) CHASE3 PF05227.8 EEQ31552.1 - 3.3 7.3 11.5 0.21 11.2 4.1 1.9 2 0 0 2 2 2 0 CHASE3 domain DUF663 PF04950.7 EEQ31553.1 - 1.2e-92 310.0 0.0 2.7e-92 308.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EEQ31553.1 - 3.1e-13 49.0 0.0 7.5e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain HlyIII PF03006.15 EEQ31554.1 - 4.3e-54 183.2 17.9 5.2e-54 182.9 12.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3397 PF11877.3 EEQ31554.1 - 0.037 14.0 4.3 0.3 11.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3397) ESSS PF10183.4 EEQ31554.1 - 1.5 9.2 5.7 27 5.1 0.2 3.1 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF726 PF05277.7 EEQ31555.1 - 1.5e-114 382.4 0.3 2.1e-114 382.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glu-tRNAGln PF02686.10 EEQ31555.1 - 0.00011 21.9 0.4 0.00032 20.4 0.3 1.8 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Abhydrolase_6 PF12697.2 EEQ31555.1 - 0.00014 21.8 0.1 0.00014 21.8 0.1 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EEQ31555.1 - 0.0018 18.5 0.1 0.0089 16.2 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.2 EEQ31555.1 - 0.012 15.3 0.5 0.039 13.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ31555.1 - 0.016 14.7 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 EEQ31555.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 EEQ31555.1 - 0.08 12.5 0.1 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) SNAP PF14938.1 EEQ31556.1 - 5.5e-105 350.5 18.7 6.9e-105 350.2 13.0 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EEQ31556.1 - 6.9e-08 32.3 10.2 0.0012 18.7 0.4 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ31556.1 - 0.001 18.8 12.1 9.1 6.4 0.5 6.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ31556.1 - 0.02 14.5 12.0 2.8 7.6 2.6 3.6 1 1 1 2 2 2 0 TPR repeat TPR_6 PF13174.1 EEQ31556.1 - 0.083 13.3 10.5 16 6.2 0.1 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ31556.1 - 0.14 11.9 9.1 16 5.5 0.6 5.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ31556.1 - 0.17 12.6 10.1 9.7 7.1 0.8 4.7 1 1 5 6 6 6 0 Tetratricopeptide repeat NSF PF02071.15 EEQ31556.1 - 3.3 8.6 20.3 1.6 9.6 0.1 6.3 7 0 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.1 EEQ31556.1 - 4.6 7.2 12.0 15 5.6 0.2 5.4 3 2 3 6 6 6 0 Tetratricopeptide repeat Ank_2 PF12796.2 EEQ31557.1 - 4.7e-05 23.6 1.1 0.0011 19.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) AAA PF00004.24 EEQ31557.1 - 0.0013 18.9 0.0 0.0034 17.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ31557.1 - 0.002 18.9 0.0 0.0069 17.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Ank PF00023.25 EEQ31557.1 - 0.0027 17.4 1.4 4.3 7.3 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 EEQ31557.1 - 0.0038 17.6 0.1 0.36 11.4 0.0 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ31557.1 - 0.011 15.8 0.6 6.8 7.2 0.0 4.1 4 0 0 4 4 3 0 Ankyrin repeat ClpB_D2-small PF10431.4 EEQ31557.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_18 PF13238.1 EEQ31557.1 - 0.016 15.5 0.1 0.11 12.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EEQ31557.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEQ31557.1 - 0.03 14.2 0.0 0.098 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 EEQ31557.1 - 0.035 12.9 0.1 0.062 12.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.8 EEQ31557.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EEQ31557.1 - 0.091 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase EcsB PF05975.7 EEQ31558.1 - 0.6 8.5 5.1 0.94 7.8 3.5 1.3 1 1 0 1 1 1 0 Bacterial ABC transporter protein EcsB Antimicrobial12 PF08107.6 EEQ31559.1 - 0.28 10.7 3.5 0.15 11.6 0.6 1.8 2 0 0 2 2 2 0 Pleurocidin family zf-dskA_traR PF01258.12 EEQ31559.1 - 2.5 7.8 10.4 2.4 7.9 0.4 2.6 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Cupin_1 PF00190.17 EEQ31560.1 - 2.9e-25 88.3 0.0 3.7e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EEQ31560.1 - 2.5e-18 65.3 0.8 4.9e-10 38.7 0.1 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EEQ31560.1 - 5.4e-05 22.4 0.1 0.048 13.0 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EEQ31560.1 - 0.0012 18.5 0.0 2 7.9 0.0 3.1 1 1 2 3 3 3 2 Cupin DUF760 PF05542.6 EEQ31561.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF760) Sec62 PF03839.11 EEQ31564.1 - 2.7e-51 174.1 0.2 2.7e-51 174.1 0.1 2.1 2 0 0 2 2 2 1 Translocation protein Sec62 Zip PF02535.17 EEQ31564.1 - 0.0019 17.2 1.3 0.98 8.3 2.2 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter SinI PF08671.5 EEQ31564.1 - 0.15 11.4 0.5 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Anti-repressor SinI Shisa PF13908.1 EEQ31564.1 - 0.58 10.3 18.6 5.5 7.1 0.1 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Suf PF05843.9 EEQ31564.1 - 0.63 9.7 14.5 10 5.7 8.2 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.8 EEQ31564.1 - 8.6 5.0 27.1 16 4.1 18.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.8 EEQ31564.1 - 9.6 6.2 26.8 0.27 11.3 5.5 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lectin_C PF00059.16 EEQ31565.1 - 0.00011 22.7 1.6 0.00015 22.3 0.4 1.8 2 0 0 2 2 2 1 Lectin C-type domain Pyr_redox_2 PF07992.9 EEQ31566.1 - 8.6e-05 22.4 0.0 0.0018 18.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ31566.1 - 0.00013 22.0 0.0 0.46 10.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ31566.1 - 0.016 15.2 0.0 0.054 13.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEQ31566.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EEQ31566.1 - 0.14 10.5 0.0 0.22 9.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EEQ31566.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain priB_priC PF07445.7 EEQ31567.1 - 0.003 17.0 0.4 0.003 17.0 0.3 1.6 2 0 0 2 2 2 1 Primosomal replication protein priB and priC bZIP_1 PF00170.16 EEQ31567.1 - 0.021 14.7 1.6 0.026 14.4 0.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF2968 PF11180.3 EEQ31567.1 - 0.093 12.0 0.1 0.093 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) SPX PF03105.14 EEQ31567.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.2 1 1 0 2 2 2 0 SPX domain DUF2046 PF09755.4 EEQ31567.1 - 0.26 10.1 8.5 0.045 12.6 3.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DASH_Spc34 PF08657.5 EEQ31567.1 - 1.3 8.5 7.6 3.3 7.3 0.8 2.5 3 0 0 3 3 3 0 DASH complex subunit Spc34 FlaC_arch PF05377.6 EEQ31567.1 - 1.8 8.4 4.3 4.1 7.3 1.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Carn_acyltransf PF00755.15 EEQ31568.1 - 2.8e-181 603.6 0.0 3.2e-181 603.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.5 EEQ31569.1 - 1.5e-26 92.8 0.0 1.8e-25 89.4 0.0 2.5 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EEQ31569.1 - 0.00023 21.0 0.0 0.0028 17.5 0.0 2.3 2 0 0 2 2 2 1 LCCL domain Adenyl_cycl_N PF12633.2 EEQ31570.1 - 0.032 13.7 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase NT domain Hum_adeno_E3A PF05393.6 EEQ31570.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein CLN3 PF02487.12 EEQ31572.1 - 4.5e-96 322.0 22.1 2.2e-93 313.2 15.3 2.8 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 EEQ31572.1 - 2.5e-06 26.4 3.2 2.5e-06 26.4 2.2 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 EEQ31573.1 - 6.1e-35 120.7 0.0 1.9e-24 86.4 0.0 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 EEQ31573.1 - 0.061 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) Aminotran_3 PF00202.16 EEQ31574.1 - 3.8e-90 302.1 0.0 6.6e-90 301.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEQ31574.1 - 5.5e-05 22.2 0.0 0.00016 20.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DUF1674 PF07896.7 EEQ31575.1 - 1.6e-16 60.2 5.2 2.6e-16 59.5 3.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) MSA_2 PF00985.12 EEQ31575.1 - 0.3 11.2 1.3 0.33 11.0 0.9 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family HMGL-like PF00682.14 EEQ31576.1 - 1e-37 130.0 0.0 4.2e-37 128.0 0.0 1.8 1 1 0 1 1 1 1 HMGL-like Diphthamide_syn PF01866.12 EEQ31577.1 - 4e-115 384.2 0.0 4.7e-115 384.0 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Bromodomain PF00439.20 EEQ31578.1 - 5.1e-14 51.9 0.0 1.4e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Bromodomain DUF2201_N PF13203.1 EEQ31578.1 - 0.027 13.6 0.9 0.064 12.4 0.6 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain CAP-ZIP_m PF15255.1 EEQ31579.1 - 0.039 13.8 0.6 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region OSCP PF00213.13 EEQ31580.1 - 1.3e-42 145.6 2.1 1.8e-42 145.1 1.5 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Mob1_phocein PF03637.12 EEQ31581.1 - 4.8e-71 238.0 0.1 6e-71 237.7 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Rgp1 PF08737.5 EEQ31582.1 - 1.2e-105 353.9 0.0 2.6e-105 352.8 0.0 1.6 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 EEQ31582.1 - 0.00075 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EEQ31582.1 - 0.028 14.5 1.5 0.61 10.1 0.0 3.4 4 1 0 4 4 4 0 Arrestin (or S-antigen), C-terminal domain Neugrin PF06413.6 EEQ31583.1 - 4.5e-10 39.7 1.1 7.8e-10 38.9 0.8 1.5 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EEQ31583.1 - 1.6e-06 28.1 13.4 7.4e-06 26.0 9.3 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_7 PF02796.10 EEQ31583.1 - 0.03 14.2 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_DeoR PF08220.7 EEQ31583.1 - 0.036 13.5 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_23 PF13384.1 EEQ31583.1 - 0.06 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EEQ31583.1 - 0.061 12.5 0.0 0.14 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Pdase_C33_assoc PF14756.1 EEQ31584.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C33-associated domain KR PF08659.5 EEQ31585.1 - 4.6e-62 208.9 0.5 8.5e-62 208.0 0.3 1.5 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.21 EEQ31585.1 - 1e-54 185.7 0.6 4.1e-44 150.9 0.0 2.9 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EEQ31585.1 - 1.7e-50 171.8 0.0 3.2e-50 170.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EEQ31585.1 - 2.2e-50 171.7 0.2 9.3e-50 169.7 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 EEQ31585.1 - 8.8e-45 152.6 0.5 1.9e-44 151.5 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEQ31585.1 - 1.8e-38 131.0 0.1 5.5e-38 129.4 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.1 EEQ31585.1 - 2.5e-10 41.3 0.0 1.1e-09 39.2 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEQ31585.1 - 6.1e-10 38.7 0.1 3.7e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ31585.1 - 0.00024 20.8 0.3 0.00055 19.6 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EEQ31585.1 - 0.014 15.6 0.0 0.056 13.7 0.0 2.1 1 0 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EEQ31585.1 - 0.033 14.6 0.0 0.094 13.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.1 EEQ31585.1 - 0.036 13.8 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EEQ31585.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EEQ31586.1 - 1.6e-19 70.2 0.0 5e-19 68.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EEQ31586.1 - 0.0014 19.0 0.7 0.0079 16.5 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EEQ31586.1 - 0.0052 15.6 0.0 0.57 8.9 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase DAO PF01266.19 EEQ31586.1 - 0.015 14.1 1.6 0.036 12.9 0.8 1.7 1 1 0 2 2 2 0 FAD dependent oxidoreductase ketoacyl-synt PF00109.21 EEQ31587.1 - 1.7e-64 217.7 0.0 3.4e-64 216.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEQ31587.1 - 5.3e-34 116.6 0.0 1.1e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EEQ31587.1 - 1e-28 100.5 0.0 2.7e-28 99.2 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 EEQ31587.1 - 3.4e-28 98.2 0.0 5.4e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EEQ31587.1 - 1.7e-08 34.5 0.8 4.2e-08 33.3 0.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EEQ31587.1 - 2.5e-06 27.1 0.0 9.4e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 EEQ31587.1 - 0.00011 21.3 0.0 0.00038 19.5 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short PF00106.20 EEQ31587.1 - 0.00041 20.3 0.1 0.0013 18.6 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ31587.1 - 0.0055 16.3 0.5 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 EEQ31587.1 - 0.03 13.0 0.0 4.8 5.8 0.0 2.7 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family ICMT PF04140.9 EEQ31588.1 - 5e-29 100.3 0.2 5e-29 100.3 0.1 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EEQ31588.1 - 2.4e-14 53.3 1.2 2.4e-14 53.3 0.9 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EEQ31588.1 - 1.2e-05 24.7 0.2 1.9e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Herpes_UL43 PF05072.8 EEQ31590.1 - 0.00086 18.1 0.1 0.00093 18.0 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL43 protein Tmemb_170 PF10190.4 EEQ31590.1 - 0.087 12.8 4.7 0.11 12.5 3.3 1.1 1 0 0 1 1 1 0 Putative transmembrane protein 170 APH PF01636.18 EEQ31591.1 - 1.2e-07 31.7 0.0 2.9e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ31592.1 - 1.8e-32 112.5 0.0 2.3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31592.1 - 1.7e-12 46.9 0.1 5.2e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Cwf_Cwc_15 PF04889.7 EEQ31594.1 - 2.8e-87 292.4 13.1 3.1e-87 292.3 9.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EEQ31594.1 - 1.9e-05 24.2 3.8 2.6e-05 23.7 2.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2890 PF11081.3 EEQ31594.1 - 0.0068 16.4 13.5 0.0077 16.3 8.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2890) Nop53 PF07767.6 EEQ31594.1 - 0.04 12.9 14.0 0.05 12.5 9.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.7 EEQ31594.1 - 0.26 10.5 18.3 0.32 10.2 12.7 1.1 1 0 0 1 1 1 0 SDA1 APG6 PF04111.7 EEQ31594.1 - 2.5 7.0 9.5 3.2 6.7 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CDC45 PF02724.9 EEQ31594.1 - 3 5.7 15.8 3.6 5.4 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein EMP24_GP25L PF01105.19 EEQ31594.1 - 6.6 6.4 6.7 10 5.7 4.6 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Mac PF12464.3 EEQ31597.1 - 0.076 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Maltose acetyltransferase APH PF01636.18 EEQ31598.1 - 9.4e-12 45.1 0.0 1.1e-10 41.6 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Med22 PF06179.7 EEQ31599.1 - 2.7e-22 78.8 2.0 3.3e-22 78.5 1.4 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex GPW_gp25 PF04965.9 EEQ31599.1 - 0.034 13.6 1.9 0.053 13.0 0.2 1.9 2 0 0 2 2 2 0 Gene 25-like lysozyme DHFR_1 PF00186.14 EEQ31600.1 - 4.5e-18 65.3 0.2 7.5e-12 45.1 0.1 3.9 1 1 1 2 2 2 2 Dihydrofolate reductase Voltage_CLC PF00654.15 EEQ31601.1 - 2.2e-94 316.3 23.6 3.5e-94 315.7 13.7 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel Btz PF09405.5 EEQ31601.1 - 0.091 12.8 1.2 0.15 12.0 0.8 1.2 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF3848 PF12959.2 EEQ31601.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Lipase_GDSL_2 PF13472.1 EEQ31603.1 - 8.7e-17 61.8 0.0 1.3e-14 54.7 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ31603.1 - 3e-14 53.4 0.0 8.4e-08 32.3 0.0 2.1 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase APH PF01636.18 EEQ31606.1 - 2.7e-13 50.2 0.0 4.2e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ31606.1 - 0.021 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box-like PF12937.2 EEQ31607.1 - 2.2e-05 24.0 0.2 2.2e-05 24.0 0.1 2.3 3 0 0 3 3 3 1 F-box-like FAM91_N PF14647.1 EEQ31607.1 - 0.095 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus Isochorismatase PF00857.15 EEQ31611.1 - 1.8e-25 89.8 0.0 2.2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family HK PF02110.10 EEQ31612.1 - 1.5e-71 240.4 2.7 1e-69 234.4 0.3 2.7 2 1 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EEQ31612.1 - 4.8e-59 198.4 4.1 7.7e-59 197.8 2.8 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI QRPTase_C PF01729.14 EEQ31612.1 - 0.046 13.2 0.1 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain eIF-5_eIF-2B PF01873.12 EEQ31613.1 - 4.7e-39 132.8 0.0 7.3e-39 132.2 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EEQ31613.1 - 1.2e-24 86.0 1.9 1.6e-24 85.6 0.3 2.1 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Dicer_dimer PF03368.9 EEQ31614.1 - 0.0096 15.6 0.0 0.036 13.8 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain PT PF04886.7 EEQ31615.1 - 6.7 6.1 21.3 0.036 13.3 4.0 3.7 3 1 0 3 3 3 0 PT repeat DNA_ligase_A_M PF01068.16 EEQ31616.1 - 2.9e-57 193.3 0.2 2.6e-45 154.2 0.1 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEQ31616.1 - 1.9e-54 184.1 0.2 3.6e-54 183.2 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEQ31616.1 - 1.3e-27 96.0 0.6 6.5e-27 93.7 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Synaptonemal_3 PF15191.1 EEQ31616.1 - 0.032 13.9 0.2 0.48 10.2 0.0 2.7 2 1 1 3 3 3 0 Synaptonemal complex central element protein 3 mRNA_cap_enzyme PF01331.14 EEQ31617.1 - 6.9e-52 175.9 1.0 9.4e-52 175.5 0.7 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EEQ31617.1 - 1.4e-24 86.4 0.0 2.8e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EEQ31617.1 - 1.3e-08 34.4 1.2 4.2e-07 29.5 0.8 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain SCA7 PF08313.7 EEQ31618.1 - 6.7e-34 115.3 0.6 6.7e-34 115.3 0.4 2.7 3 0 0 3 3 3 1 SCA7, zinc-binding domain Neugrin PF06413.6 EEQ31618.1 - 0.37 10.5 9.7 0.67 9.7 6.7 1.4 1 0 0 1 1 1 0 Neugrin CDC45 PF02724.9 EEQ31618.1 - 2.9 5.8 6.8 4.3 5.2 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein AIRC PF00731.15 EEQ31619.1 - 3.5e-59 198.4 2.1 6.2e-59 197.5 1.5 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EEQ31619.1 - 3.2e-52 176.3 0.0 6.7e-52 175.3 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EEQ31619.1 - 3.2e-09 36.7 0.0 1.9e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EEQ31619.1 - 3.7e-06 26.3 0.3 1.3e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PrpR_N PF06506.6 EEQ31619.1 - 0.0013 18.1 0.6 0.02 14.3 0.1 2.5 2 0 0 2 2 2 1 Propionate catabolism activator Dala_Dala_lig_C PF07478.8 EEQ31619.1 - 0.0032 16.8 0.0 0.09 12.1 0.0 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CoA_binding_2 PF13380.1 EEQ31619.1 - 0.02 15.0 1.6 9.3 6.4 0.1 3.3 2 1 1 3 3 3 0 CoA binding domain 2-Hacid_dh_C PF02826.14 EEQ31619.1 - 0.066 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EIN3 PF04873.8 EEQ31619.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Ethylene insensitive 3 Ank_2 PF12796.2 EEQ31620.1 - 4.6e-52 174.3 4.9 1.5e-15 57.2 0.0 4.9 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ31620.1 - 2.2e-50 166.0 13.6 1.2e-08 34.2 0.0 10.3 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.1 EEQ31620.1 - 6.2e-41 137.5 11.2 2.1e-12 46.8 0.1 6.8 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ31620.1 - 1.4e-38 130.6 8.0 1.8e-13 50.5 0.1 6.8 4 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ31620.1 - 2.4e-38 126.3 8.3 4e-06 26.5 0.1 9.4 10 0 0 10 10 10 5 Ankyrin repeat Mac PF12464.3 EEQ31621.1 - 1.4e-15 56.9 0.1 2.4e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 EEQ31621.1 - 1.4e-14 52.8 9.8 5e-11 41.5 3.6 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEQ31621.1 - 9.4e-11 41.0 10.3 3.4e-10 39.3 2.8 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase RNase_P_pop3 PF08228.6 EEQ31622.1 - 0.0023 17.8 0.0 0.0048 16.7 0.0 1.6 1 1 0 1 1 1 1 RNase P subunit Pop3 ketoacyl-synt PF00109.21 EEQ31623.1 - 2.1e-72 243.6 0.1 4.8e-72 242.4 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ31623.1 - 1e-41 143.3 0.0 1.9e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEQ31623.1 - 2.4e-32 111.2 0.9 7.5e-32 109.6 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EEQ31623.1 - 4.1e-11 42.9 0.9 1e-10 41.7 0.7 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EEQ31623.1 - 9.8e-05 21.4 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EEQ31623.1 - 0.022 14.4 0.0 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1772 PF08592.6 EEQ31624.1 - 1.9e-08 34.1 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) NicO PF03824.11 EEQ31624.1 - 0.021 14.1 0.2 0.18 11.0 0.1 2.0 2 0 0 2 2 2 0 High-affinity nickel-transport protein Lactamase_B PF00753.22 EEQ31625.1 - 1.4e-16 60.7 5.0 2.8e-16 59.7 3.1 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEQ31625.1 - 0.0005 19.6 0.1 0.00081 18.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_2 PF00891.13 EEQ31626.1 - 3.1e-06 26.5 0.7 0.0013 18.0 0.5 2.9 1 1 0 1 1 1 1 O-methyltransferase Zn_clus PF00172.13 EEQ31628.1 - 9.8e-09 34.9 10.2 2.3e-08 33.8 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_1 PF00175.16 EEQ31629.1 - 1.3e-20 73.9 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEQ31629.1 - 3.1e-14 52.8 0.0 5.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEQ31629.1 - 3.1e-06 27.1 0.0 0.0024 17.7 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EEQ31629.1 - 0.043 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Epimerase PF01370.16 EEQ31630.1 - 7.6e-14 51.7 0.6 3.9e-13 49.3 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEQ31630.1 - 1.7e-13 51.0 2.9 1.8e-12 47.6 0.2 2.4 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEQ31630.1 - 2.4e-08 33.0 0.0 3.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EEQ31630.1 - 2.8e-06 26.7 0.1 4.7e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EEQ31630.1 - 1.7e-05 23.8 0.0 6.9e-05 21.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EEQ31630.1 - 5.3e-05 22.2 0.0 7.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EEQ31630.1 - 5.6e-05 23.1 0.5 0.00014 21.8 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Methyltransf_2 PF00891.13 EEQ31631.1 - 4.4e-26 91.5 0.0 7.3e-26 90.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase DUF3517 PF12030.3 EEQ31633.1 - 3e-114 381.0 0.9 9.8e-114 379.3 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.24 EEQ31633.1 - 4.5e-44 150.5 0.0 8.5e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ31633.1 - 5.8e-19 68.6 0.0 1.4e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TrkH PF02386.11 EEQ31634.1 - 4.1e-93 311.7 17.7 9.1e-91 304.0 5.4 3.3 2 2 0 2 2 2 2 Cation transport protein TFIIE_alpha PF02002.12 EEQ31635.1 - 2.5e-18 65.4 0.0 4.6e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_Crp_2 PF13545.1 EEQ31635.1 - 0.013 15.2 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain zf-FPG_IleRS PF06827.9 EEQ31635.1 - 0.041 13.5 1.2 4 7.1 0.0 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS PseudoU_synth_1 PF01416.15 EEQ31636.1 - 8.2e-24 84.0 0.0 6.5e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase ATP_bind_2 PF03668.10 EEQ31636.1 - 0.07 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family Anillin PF08174.6 EEQ31637.1 - 9.6e-32 109.9 0.2 3.1e-31 108.3 0.2 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EEQ31637.1 - 1.2e-08 35.0 0.0 5.1e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 PH domain DEAD PF00270.24 EEQ31638.1 - 1.3e-31 109.3 0.1 3.1e-31 108.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ31638.1 - 5.9e-17 61.3 0.0 1.8e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ31638.1 - 3e-05 22.9 0.0 4.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EEQ31638.1 - 0.002 18.0 0.1 0.0081 16.0 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Cucumo_2B PF03263.8 EEQ31639.1 - 0.62 10.3 7.3 2.5 8.4 0.5 2.2 1 1 1 2 2 2 0 Cucumovirus protein 2B SET PF00856.23 EEQ31641.1 - 6.3e-10 39.5 0.0 1.7e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 SET domain HypA PF01155.14 EEQ31641.1 - 0.096 12.3 0.3 0.28 10.8 0.2 1.7 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family APH PF01636.18 EEQ31642.1 - 1.2e-08 35.0 0.0 2.4e-07 30.7 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ31642.1 - 0.039 13.5 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ31642.1 - 0.086 11.9 0.1 0.33 10.0 0.0 1.9 1 1 1 2 2 2 0 Protein kinase domain Ribosomal_L14 PF00238.14 EEQ31643.1 - 6.6e-46 155.0 1.7 7.4e-46 154.8 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_POL_M_15KD PF02150.11 EEQ31644.1 - 1.9e-11 43.4 0.8 1.9e-11 43.4 0.6 2.8 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit FYVE PF01363.16 EEQ31644.1 - 0.15 11.9 7.8 1.4 8.8 0.8 2.3 2 0 0 2 2 2 0 FYVE zinc finger GFA PF04828.9 EEQ31644.1 - 0.17 11.8 5.9 0.15 12.0 1.4 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Rotamase PF00639.16 EEQ31646.1 - 8.2e-22 77.7 0.1 1.2e-21 77.2 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EEQ31646.1 - 5.1e-15 55.7 0.0 7.1e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EEQ31646.1 - 4.5e-06 27.2 0.0 6.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WD40 PF00400.27 EEQ31648.1 - 0.0033 17.2 0.4 0.07 13.0 0.2 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat RRM_1 PF00076.17 EEQ31649.1 - 1.6e-15 56.5 0.0 2.4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31649.1 - 4.9e-12 45.6 0.0 8.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ31649.1 - 1.3e-08 34.5 0.0 2.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNO PF01174.14 EEQ31650.1 - 1.2e-53 181.5 0.0 4e-43 147.2 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EEQ31650.1 - 3.3e-09 36.5 0.0 2.8e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EEQ31650.1 - 4.4e-05 23.0 0.0 0.00039 19.9 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EEQ31650.1 - 8.1e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EEQ31650.1 - 0.00017 20.8 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 EEQ31650.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S51 ACPS PF01648.15 EEQ31652.1 - 3.3e-12 46.2 0.0 5.6e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.16 EEQ31653.1 - 4.8e-31 106.9 0.0 8.1e-31 106.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TPR_1 PF00515.23 EEQ31654.1 - 1.5e-42 141.5 6.3 9.8e-09 34.4 0.0 7.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ31654.1 - 4.1e-40 135.2 20.7 1.4e-13 50.2 0.9 7.6 6 2 2 8 8 7 7 TPR repeat TPR_2 PF07719.12 EEQ31654.1 - 4.5e-37 122.9 12.8 3.2e-06 26.6 0.0 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat Apc3 PF12895.2 EEQ31654.1 - 1.2e-30 105.4 15.4 1.3e-21 76.4 0.1 5.2 3 1 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EEQ31654.1 - 3.5e-28 97.6 11.3 1.5e-09 38.2 0.2 8.1 6 2 2 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ31654.1 - 6.4e-28 94.4 1.6 0.00026 20.5 0.2 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ31654.1 - 2.5e-26 91.7 8.6 9.6e-08 32.2 0.6 7.0 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ31654.1 - 7.3e-23 80.3 15.4 2.8e-05 23.9 0.1 7.6 3 2 4 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ31654.1 - 1.5e-21 74.9 4.8 0.043 14.4 0.0 9.4 6 1 2 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ31654.1 - 3.4e-16 58.0 12.3 0.002 18.1 0.0 9.4 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ31654.1 - 2.9e-14 51.6 3.0 0.0026 17.4 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ31654.1 - 2.5e-10 40.1 5.0 0.71 10.4 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ31654.1 - 5.8e-07 29.2 1.1 0.017 14.9 0.0 4.9 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ31654.1 - 0.00028 20.0 3.7 2.3 7.2 0.0 4.1 2 2 2 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 EEQ31654.1 - 0.00074 18.3 0.1 0.2 10.3 0.0 2.6 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.18 EEQ31654.1 - 0.0013 17.8 1.7 0.024 13.6 0.0 3.0 2 1 1 3 3 3 1 FAT domain MIT PF04212.13 EEQ31654.1 - 0.0086 15.9 2.2 0.35 10.7 0.1 4.0 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 EEQ31654.1 - 0.13 12.1 3.4 6.1 6.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 EEQ31654.1 - 1.2 8.5 6.1 18 4.7 0.3 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF788 PF05620.6 EEQ31655.1 - 3.9e-43 147.2 0.0 4.4e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF1441 PF07278.6 EEQ31656.1 - 0.015 14.9 0.0 5.2 6.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1441) PEP-utilisers_N PF05524.8 EEQ31656.1 - 0.26 11.0 5.5 0.96 9.2 0.0 4.0 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal ABC_tran PF00005.22 EEQ31657.1 - 9e-42 142.6 0.0 1.9e-20 73.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ31657.1 - 1.9e-24 86.5 25.9 6.1e-22 78.3 7.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEQ31657.1 - 6.2e-14 52.6 0.4 5.2e-06 26.6 0.0 4.9 3 2 0 4 4 4 2 AAA domain SMC_N PF02463.14 EEQ31657.1 - 6.3e-10 38.6 3.9 0.0046 16.2 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEQ31657.1 - 3.1e-08 33.8 0.2 0.0065 16.4 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EEQ31657.1 - 9.6e-08 31.4 0.1 0.017 14.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EEQ31657.1 - 4.6e-07 30.0 0.0 0.037 14.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEQ31657.1 - 5.2e-07 30.5 0.0 0.014 16.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEQ31657.1 - 1.4e-06 28.6 0.0 0.048 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EEQ31657.1 - 2.4e-05 24.0 0.1 0.089 12.5 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEQ31657.1 - 2.9e-05 23.9 0.0 0.029 14.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EEQ31657.1 - 4.4e-05 22.7 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 EEQ31657.1 - 6.6e-05 21.9 0.0 0.026 13.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 EEQ31657.1 - 6.8e-05 23.2 0.3 0.26 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ31657.1 - 7.3e-05 22.7 0.4 0.31 10.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 EEQ31657.1 - 0.0001 22.1 1.1 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 EEQ31657.1 - 0.00014 21.6 0.8 1.7 8.6 0.1 3.9 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EEQ31657.1 - 0.00017 22.0 0.1 0.03 14.8 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EEQ31657.1 - 0.00039 20.2 0.1 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.1 EEQ31657.1 - 0.00054 19.4 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEQ31657.1 - 0.0006 20.0 0.0 0.41 10.8 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.10 EEQ31657.1 - 0.00065 18.4 0.0 0.49 8.9 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein AAA_10 PF12846.2 EEQ31657.1 - 0.00089 18.7 1.3 0.25 10.7 0.2 2.4 2 0 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EEQ31657.1 - 0.0041 16.6 0.0 0.64 9.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EEQ31657.1 - 0.0042 16.1 0.0 2 7.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin ATP_bind_1 PF03029.12 EEQ31657.1 - 0.0077 15.8 0.1 0.14 11.6 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.14 EEQ31657.1 - 0.012 15.0 0.2 0.95 8.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EEQ31657.1 - 0.016 14.9 0.0 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 EEQ31657.1 - 0.022 14.4 0.2 1 9.1 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 EEQ31657.1 - 0.024 13.8 0.2 7 5.7 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEQ31657.1 - 0.025 14.7 0.0 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 EEQ31657.1 - 0.041 13.5 0.0 4 7.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 EEQ31657.1 - 0.06 13.0 0.9 15 5.3 0.0 3.4 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EEQ31657.1 - 0.1 12.0 0.6 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 EEQ31657.1 - 0.11 11.3 0.0 18 4.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.16 EEQ31657.1 - 0.17 11.2 0.1 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase GTP_EFTU PF00009.22 EEQ31657.1 - 0.17 11.2 0.0 4.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EEQ31657.1 - 0.33 10.4 0.2 22 4.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain RINGv PF12906.2 EEQ31659.1 - 1.5e-15 56.9 10.9 2.5e-15 56.2 7.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EEQ31659.1 - 0.098 12.4 8.5 0.18 11.6 5.9 1.4 1 0 0 1 1 1 0 Ring finger domain S1FA PF04689.8 EEQ31659.1 - 0.26 11.1 0.4 0.89 9.4 0.3 1.9 1 0 0 1 1 1 0 DNA binding protein S1FA zf-C3HC4_3 PF13920.1 EEQ31659.1 - 0.33 10.6 6.0 0.55 9.9 4.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ31659.1 - 0.43 10.4 3.3 0.91 9.3 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEQ31659.1 - 0.93 9.1 6.8 1.6 8.3 4.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EEQ31659.1 - 5.1 7.1 6.9 11 6.0 4.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain HeLo PF14479.1 EEQ31660.1 - 0.15 11.7 0.1 0.87 9.2 0.1 2.1 1 1 0 1 1 1 0 Prion-inhibition and propagation ACC_central PF08326.7 EEQ31661.1 - 6.3e-261 867.5 0.0 8.2e-261 867.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EEQ31661.1 - 6.3e-167 555.8 0.0 1.5e-165 551.3 0.0 2.4 2 1 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EEQ31661.1 - 3.1e-54 183.4 0.0 5.9e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EEQ31661.1 - 1.1e-24 86.6 0.1 2.1e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EEQ31661.1 - 2e-23 82.4 0.0 1.2e-19 70.2 0.0 3.6 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EEQ31661.1 - 2.2e-15 56.0 0.2 6.4e-15 54.5 0.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EEQ31661.1 - 2.9e-11 43.4 0.0 7.4e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEQ31661.1 - 2.4e-09 36.4 0.0 1.7e-07 30.3 0.0 3.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEQ31661.1 - 1.2e-05 24.8 0.0 2.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EEQ31661.1 - 0.00044 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EEQ31661.1 - 0.007 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Gryzun PF07919.7 EEQ31661.1 - 0.19 9.9 0.0 0.33 9.2 0.0 1.2 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi NUDE_C PF04880.8 EEQ31662.1 - 2e-22 80.3 8.3 2e-22 80.3 5.8 4.7 3 2 0 3 3 3 1 NUDE protein, C-terminal conserved region DMPK_coil PF08826.5 EEQ31662.1 - 0.011 15.6 1.2 0.011 15.6 0.8 4.4 2 1 3 5 5 5 0 DMPK coiled coil domain like V_ATPase_I PF01496.14 EEQ31662.1 - 0.015 13.1 9.1 0.023 12.5 6.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 EEQ31662.1 - 0.019 15.2 7.7 0.019 15.2 5.3 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF904) WEMBL PF05701.6 EEQ31662.1 - 0.067 11.6 25.7 0.11 10.9 17.8 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light ADIP PF11559.3 EEQ31662.1 - 0.42 10.5 24.7 1.1 9.1 3.6 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.9 EEQ31662.1 - 0.64 9.4 4.8 0.3 10.4 0.4 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.7 EEQ31662.1 - 0.82 9.4 3.6 0.27 11.0 0.4 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 EEQ31662.1 - 8.9 6.1 33.4 1.9 8.3 12.5 3.4 2 1 1 3 3 3 0 Tropomyosin like Hexokinase_2 PF03727.11 EEQ31663.1 - 3e-25 88.8 0.0 8.1e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EEQ31663.1 - 8.8e-22 77.4 0.0 6.6e-21 74.5 0.0 2.2 1 1 0 1 1 1 1 Hexokinase Isochorismatase PF00857.15 EEQ31664.1 - 3.7e-37 127.9 0.0 1.7e-36 125.7 0.0 1.9 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.10 EEQ31664.1 - 2.9e-07 30.9 0.0 6.7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EEQ31664.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.8 EEQ31665.1 - 2.1e-39 134.4 0.0 2.5e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EEQ31665.1 - 0.0049 16.5 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family NLBH PF05211.7 EEQ31665.1 - 0.025 13.8 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) DUF2040 PF09745.4 EEQ31666.1 - 4.5e-41 139.6 13.7 4.5e-41 139.6 9.5 3.8 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Zip PF02535.17 EEQ31667.1 - 1.2e-25 90.2 11.7 3.6e-24 85.3 8.1 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter Endonuclease_NS PF01223.18 EEQ31668.1 - 2.8e-60 203.4 0.0 4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease BTB PF00651.26 EEQ31669.1 - 0.043 13.8 0.2 0.53 10.2 0.0 2.5 3 0 0 3 3 3 0 BTB/POZ domain Sec7 PF01369.15 EEQ31670.1 - 6e-38 130.4 0.1 1e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EEQ31670.1 - 3.6e-07 30.3 0.1 9.6e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEQ31670.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 PH domain SET PF00856.23 EEQ31671.1 - 0.0067 16.7 0.1 0.24 11.7 0.0 2.4 2 1 1 3 3 3 2 SET domain zf-C3HC4_2 PF13923.1 EEQ31672.1 - 3.3e-10 39.8 8.3 1.9e-05 24.6 0.6 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ31672.1 - 7.1e-06 25.7 10.1 0.00052 19.7 2.7 2.8 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 EEQ31672.1 - 5.6e-05 22.7 4.1 5.6e-05 22.7 2.9 2.7 2 1 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.7 EEQ31672.1 - 0.00013 21.3 1.5 0.00013 21.3 1.0 3.2 2 1 1 3 3 2 2 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EEQ31672.1 - 0.00022 20.9 3.5 0.00023 20.8 0.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger FYVE PF01363.16 EEQ31672.1 - 0.0014 18.4 13.4 0.031 14.1 4.0 4.0 2 2 1 3 3 3 2 FYVE zinc finger zf-C3HC4 PF00097.20 EEQ31672.1 - 0.0022 17.5 8.7 0.0027 17.3 0.9 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ31672.1 - 0.011 15.3 15.2 0.019 14.6 4.8 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1195 PF06708.6 EEQ31672.1 - 0.048 13.0 0.1 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) IBR PF01485.16 EEQ31672.1 - 0.052 13.4 7.7 2.3 8.1 0.3 3.7 3 0 0 3 3 3 0 IBR domain Prok-RING_4 PF14447.1 EEQ31672.1 - 0.08 12.4 3.3 0.21 11.1 1.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 UPF1_Zn_bind PF09416.5 EEQ31672.1 - 0.26 10.8 4.0 5.1 6.6 0.2 2.4 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) zf-C3HC4_4 PF15227.1 EEQ31672.1 - 0.35 10.7 12.1 0.23 11.3 3.4 3.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Atg14 PF10186.4 EEQ31672.1 - 1.7 7.5 12.2 2.5 6.9 8.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SET PF00856.23 EEQ31673.1 - 4.5e-15 56.3 0.2 3.1e-14 53.5 0.1 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EEQ31673.1 - 0.12 12.7 0.0 11 6.5 0.0 2.3 2 0 0 2 2 2 0 SAF domain Peptidase_M14 PF00246.19 EEQ31674.1 - 9.8e-67 225.4 0.0 1.4e-66 224.9 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase NicO PF03824.11 EEQ31675.1 - 1.4e-41 142.6 10.9 2.3e-38 132.1 1.8 2.4 3 0 0 3 3 3 2 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 EEQ31675.1 - 0.053 12.3 5.1 0.014 14.2 1.1 1.7 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Herpes_gE PF02480.11 EEQ31675.1 - 0.17 10.1 0.0 11 4.1 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Peptidase_S8 PF00082.17 EEQ31676.1 - 7e-49 166.4 13.7 1.1e-48 165.7 9.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ31676.1 - 2.1e-16 60.2 0.0 4e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DNA_pol_lambd_f PF10391.4 EEQ31677.1 - 4.1e-20 71.0 0.8 6.9e-20 70.3 0.6 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EEQ31677.1 - 6.7e-19 67.3 0.0 4.7e-18 64.6 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EEQ31677.1 - 7.7e-17 61.3 0.0 3.3e-15 56.1 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.1 EEQ31677.1 - 2.6e-07 30.7 0.0 6.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HAD PF12710.2 EEQ31678.1 - 6.5e-21 75.3 0.0 1.6e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEQ31678.1 - 1.8e-19 69.7 0.1 3.4e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ31678.1 - 3e-14 53.9 0.0 2.3e-13 51.0 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ31678.1 - 7.2e-13 48.3 0.0 2e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ31678.1 - 0.0016 18.1 0.4 0.017 14.7 0.1 2.3 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEQ31678.1 - 0.022 14.9 0.1 0.073 13.2 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 EEQ31679.1 - 5.1e-18 65.6 0.0 9.6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EEQ31679.1 - 4.5e-06 26.5 0.1 1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 WD40 PF00400.27 EEQ31680.1 - 7.2e-49 162.0 29.3 2.8e-09 36.5 1.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EEQ31680.1 - 0.001 18.8 0.3 0.47 10.1 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A HTH_Tnp_Tc3_2 PF01498.13 EEQ31681.1 - 1.5e-07 31.3 0.6 2e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.1 EEQ31681.1 - 2.8e-07 29.9 1.4 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.1 EEQ31681.1 - 6.6e-07 28.7 0.2 0.0006 19.3 0.0 2.2 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 EEQ31681.1 - 1.6e-06 28.2 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EEQ31681.1 - 1.4e-05 25.8 0.0 2.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.1 EEQ31681.1 - 0.00014 21.1 1.2 0.53 9.7 0.0 3.0 2 1 0 2 2 2 2 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.7 EEQ31681.1 - 0.00018 20.9 0.3 0.018 14.5 0.0 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_28 PF13518.1 EEQ31681.1 - 0.00019 21.3 0.2 0.04 13.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.2 EEQ31681.1 - 0.00067 19.4 0.0 0.95 9.3 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain CENP-B_N PF04218.8 EEQ31681.1 - 0.0017 17.6 0.3 0.091 12.1 0.1 2.2 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_IS630 PF01710.11 EEQ31681.1 - 0.0024 17.5 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Transposase HTH_11 PF08279.7 EEQ31681.1 - 0.0048 16.4 0.3 3.6 7.2 0.0 2.5 2 1 0 2 2 2 2 HTH domain TrmB PF01978.14 EEQ31681.1 - 0.0064 16.1 0.3 1.8 8.3 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.1 EEQ31681.1 - 0.012 15.7 0.1 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.10 EEQ31681.1 - 0.017 14.9 3.2 0.31 10.9 1.0 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_WhiA PF02650.9 EEQ31681.1 - 0.051 13.9 0.1 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 WhiA C-terminal HTH domain Sigma70_r1_1 PF03979.9 EEQ31681.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 HTH_10 PF04967.7 EEQ31681.1 - 0.093 12.3 0.2 7 6.3 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain HTH_17 PF12728.2 EEQ31681.1 - 0.11 12.7 0.1 3.9 7.8 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain Fe_dep_repress PF01325.14 EEQ31681.1 - 0.11 12.4 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Sigma70_r4 PF04545.11 EEQ31681.1 - 0.11 11.7 0.1 0.6 9.4 0.0 2.0 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_IS1 PF12759.2 EEQ31681.1 - 0.14 11.5 0.2 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 InsA C-terminal domain MBOAT PF03062.14 EEQ31683.1 - 7e-24 84.5 15.9 8.6e-24 84.2 10.4 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EEQ31683.1 - 0.0031 17.5 2.8 0.009 16.0 1.9 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MAPEG PF01124.13 EEQ31684.1 - 1e-23 83.3 4.5 1.3e-23 82.9 3.1 1.0 1 0 0 1 1 1 1 MAPEG family FTR1 PF03239.9 EEQ31684.1 - 0.053 12.4 0.1 0.073 12.0 0.1 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family OMPdecase PF00215.19 EEQ31685.1 - 5e-74 248.4 0.1 5.8e-74 248.2 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family HEM4 PF02602.10 EEQ31685.1 - 0.049 12.8 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD OTT_1508_deam PF14441.1 EEQ31687.1 - 9.5e-10 38.4 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase AA_permease_2 PF13520.1 EEQ31688.1 - 2.6e-42 144.8 47.2 3.7e-42 144.3 32.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ31688.1 - 1e-17 63.6 41.6 3.2e-17 62.0 28.8 1.7 1 1 0 1 1 1 1 Amino acid permease YlaH PF14036.1 EEQ31688.1 - 0.00079 19.4 1.7 0.00079 19.4 1.2 4.1 4 0 0 4 4 4 1 YlaH-like protein DUF3153 PF11353.3 EEQ31688.1 - 0.029 13.7 0.1 0.081 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Pox_A14 PF05767.7 EEQ31688.1 - 0.075 13.0 0.4 0.075 13.0 0.3 3.7 3 2 2 5 5 5 0 Poxvirus virion envelope protein A14 APH PF01636.18 EEQ31689.1 - 9.8e-10 38.5 0.1 4.5e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ31689.1 - 0.0014 17.7 0.0 0.0066 15.6 0.0 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 EEQ31689.1 - 0.0037 16.8 0.1 0.009 15.6 0.1 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ31689.1 - 0.019 13.6 0.1 0.072 11.7 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1679) Aminotran_1_2 PF00155.16 EEQ31691.1 - 1.4e-69 234.7 0.0 1.8e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4246 PF14033.1 EEQ31692.1 - 3e-198 659.5 0.0 3.5e-198 659.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EEQ31692.1 - 0.0018 18.5 0.0 0.0051 17.0 0.0 1.8 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 EEQ31692.1 - 0.06 13.8 0.9 0.19 12.2 0.1 2.3 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily AAA_assoc PF14363.1 EEQ31692.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA DUF4066 PF13278.1 EEQ31693.1 - 5.1e-28 97.4 0.0 6.3e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEQ31693.1 - 3.1e-15 55.8 0.0 4e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EEQ31693.1 - 0.034 13.5 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I IMS PF00817.15 EEQ31694.1 - 5.3e-39 133.3 0.0 1.1e-38 132.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EEQ31694.1 - 6.7e-21 74.5 0.0 1.7e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EEQ31694.1 - 2.9e-12 46.4 5.3 4.7e-06 26.4 0.6 3.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EEQ31694.1 - 1.3e-06 28.4 0.0 1.3e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EEQ31694.1 - 0.00014 21.6 0.2 0.00063 19.6 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif HHH_5 PF14520.1 EEQ31694.1 - 0.00074 19.6 0.0 0.0028 17.8 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain PTCB-BRCT PF12738.2 EEQ31694.1 - 0.0019 18.0 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain F420_ligase PF01996.11 EEQ31694.1 - 0.067 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase Y2_Tnp PF04986.8 EEQ31694.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Putative transposase FKBP_C PF00254.23 EEQ31695.1 - 2.9e-30 104.1 0.1 1.1e-29 102.2 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Daxx PF03344.10 EEQ31695.1 - 8.3 4.7 45.1 0.95 7.8 14.1 2.1 2 0 0 2 2 2 0 Daxx Family Pkinase PF00069.20 EEQ31696.1 - 4.5e-48 163.6 0.3 5.6e-28 97.8 0.2 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31696.1 - 1.6e-19 69.9 0.0 2.8e-13 49.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEQ31696.1 - 0.026 14.2 0.1 0.026 14.2 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3591 PF12157.3 EEQ31697.1 - 3.3e-176 586.1 4.1 1.2e-90 304.1 0.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EEQ31697.1 - 0.0032 17.1 1.0 0.0073 15.9 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EEQ31697.1 - 0.014 15.3 0.9 0.025 14.4 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_15 PF09445.5 EEQ31698.1 - 2.2e-48 163.9 0.0 2.8e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EEQ31698.1 - 2.2e-10 40.4 0.0 2.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EEQ31698.1 - 2.7e-09 37.0 0.0 3.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EEQ31698.1 - 5.6e-08 32.5 0.0 7.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 EEQ31698.1 - 1.4e-07 32.0 0.0 2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EEQ31698.1 - 6.1e-07 29.0 0.0 8.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EEQ31698.1 - 0.0002 21.0 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ31698.1 - 0.0021 18.3 0.0 0.0036 17.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.14 EEQ31698.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family MTS PF05175.9 EEQ31698.1 - 0.035 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EEQ31698.1 - 0.037 13.1 0.0 0.049 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 EEQ31698.1 - 0.041 12.9 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DNA_methylase PF00145.12 EEQ31698.1 - 0.061 12.4 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase GRASP55_65 PF04495.9 EEQ31699.1 - 6.9e-43 145.9 0.0 3.6e-41 140.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain ApoO PF09769.4 EEQ31700.1 - 7.3e-49 165.5 0.3 1.8e-48 164.2 0.1 1.6 2 0 0 2 2 2 1 Apolipoprotein O zf-C4H2 PF10146.4 EEQ31700.1 - 0.046 13.7 0.9 0.079 12.9 0.6 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Peptidase_M3 PF01432.15 EEQ31701.1 - 2.3e-121 406.0 0.0 3.3e-121 405.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF1886 PF09171.5 EEQ31701.1 - 0.025 13.6 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) Methyltransf_23 PF13489.1 EEQ31702.1 - 3.3e-23 82.1 0.0 4.8e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ31702.1 - 2e-05 24.2 0.0 0.00022 20.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ31702.1 - 0.0067 17.0 0.0 0.21 12.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain HAT PF02184.11 EEQ31702.1 - 0.017 14.8 2.0 5.2 6.9 0.0 3.5 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat Methyltransf_12 PF08242.7 EEQ31702.1 - 0.03 14.7 0.0 0.15 12.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ31702.1 - 0.053 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3846 PF12957.2 EEQ31702.1 - 0.13 11.9 0.0 8 6.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3846) Proteasome PF00227.21 EEQ31705.1 - 1.2e-46 158.3 0.0 1.5e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EEQ31705.1 - 2.1e-14 52.4 0.1 4.1e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal WD40 PF00400.27 EEQ31706.1 - 0.01 15.6 0.6 1.1 9.1 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Microtub_assoc PF07989.6 EEQ31706.1 - 0.049 13.4 0.1 3.1 7.6 0.0 2.5 1 1 1 2 2 2 0 Microtubule associated Syntaxin-6_N PF09177.6 EEQ31706.1 - 0.097 13.0 1.4 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TACC PF05010.9 EEQ31706.1 - 3.2 7.4 4.7 16 5.2 1.0 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) HMG_CoA_synt_N PF01154.12 EEQ31707.1 - 4.9e-72 241.0 0.0 7.4e-72 240.5 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 EEQ31707.1 - 3.7e-62 210.3 0.0 2.4e-61 207.7 0.0 1.9 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF3197 PF11432.3 EEQ31707.1 - 0.044 13.7 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Fungal_trans PF04082.13 EEQ31708.1 - 3.2e-14 52.4 0.1 6e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ31708.1 - 1.5e-07 31.1 9.4 2.8e-07 30.3 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Orthopox_F8 PF05886.6 EEQ31708.1 - 0.2 11.4 4.5 0.51 10.2 3.1 1.6 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Thiol-ester_cl PF10569.4 EEQ31709.1 - 0.021 14.0 0.2 0.054 12.7 0.1 1.7 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region Methyltransf_25 PF13649.1 EEQ31709.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Acetyltransf_1 PF00583.19 EEQ31710.1 - 1.5e-09 37.7 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ31710.1 - 1.3e-07 31.6 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ31710.1 - 2.2e-06 27.5 0.0 2.9e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ31710.1 - 2.4e-05 24.4 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EEQ31710.1 - 0.0021 17.3 0.0 0.019 14.1 0.0 2.0 2 0 0 2 2 2 1 MOZ/SAS family FR47 PF08445.5 EEQ31710.1 - 0.003 17.2 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Tropomodulin PF03250.9 EEQ31712.1 - 0.049 13.1 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Tropomodulin ADH_N PF08240.7 EEQ31713.1 - 0.00027 20.6 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3488 PF11992.3 EEQ31714.1 - 4.8 5.7 6.1 7.5 5.0 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) AA_permease_2 PF13520.1 EEQ31715.1 - 1.3e-52 178.8 40.2 1.5e-52 178.5 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ31715.1 - 3.1e-29 101.6 30.6 4.2e-29 101.2 21.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1072 PF06380.6 EEQ31715.1 - 1.7 8.3 5.6 5.3 6.7 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) RE_EcoO109I PF14511.1 EEQ31717.1 - 0.075 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I KH_1 PF00013.24 EEQ31718.1 - 2.9e-37 126.0 2.1 2.7e-16 58.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EEQ31718.1 - 1.5e-29 101.1 8.3 2.2e-11 43.1 1.3 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EEQ31718.1 - 9.3e-12 44.3 1.9 0.012 15.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EEQ31718.1 - 0.00022 20.8 0.2 1.8 8.2 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EEQ31718.1 - 0.0092 15.7 6.1 1.2 8.9 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain CENP-K PF11802.3 EEQ31719.1 - 0.0045 16.2 5.3 0.16 11.1 0.0 2.6 2 1 0 2 2 2 1 Centromere-associated protein K TMPIT PF07851.8 EEQ31719.1 - 0.047 12.7 4.5 0.071 12.1 0.0 2.3 2 1 0 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.5 EEQ31719.1 - 0.15 12.1 7.9 4.4 7.4 2.3 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FliD_C PF07195.7 EEQ31719.1 - 0.45 9.7 0.1 0.45 9.7 0.0 3.0 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus Abhydrolase_6 PF12697.2 EEQ31720.1 - 2.3e-13 50.5 0.0 5.7e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ31720.1 - 6.8e-11 42.1 0.0 1.8e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ31720.1 - 1.1e-09 38.2 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ31720.1 - 0.0012 18.1 0.0 0.0069 15.6 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EEQ31720.1 - 0.0048 16.3 0.0 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.3 EEQ31720.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S15 PF02129.13 EEQ31720.1 - 0.094 12.1 0.0 0.7 9.2 0.0 2.0 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MFS_1 PF07690.11 EEQ31723.1 - 6.5e-37 127.0 53.9 9.9e-24 83.7 12.9 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ31723.1 - 8.6e-08 31.1 17.5 8.6e-08 31.1 12.1 3.4 2 1 2 4 4 4 2 Sugar (and other) transporter p450 PF00067.17 EEQ31724.1 - 8.4e-62 209.1 0.0 1.1e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 EEQ31725.1 - 1.1e-24 87.0 0.0 2.1e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FSH1 PF03959.8 EEQ31725.1 - 6.2e-22 78.0 0.0 9e-21 74.2 0.0 2.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) FAD_binding_6 PF00970.19 EEQ31725.1 - 1.8e-18 66.4 0.0 3.9e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EEQ31725.1 - 8.7e-14 51.0 0.0 1.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EEQ31725.1 - 2.8e-06 27.3 0.0 0.001 18.9 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Abhydrolase_6 PF12697.2 EEQ31725.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEQ31725.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase ketoacyl-synt PF00109.21 EEQ31726.1 - 4.6e-76 255.6 0.2 8.5e-76 254.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEQ31726.1 - 2.2e-59 200.1 1.1 2.4e-58 196.7 0.1 3.0 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 EEQ31726.1 - 1.2e-57 195.6 0.0 2.2e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EEQ31726.1 - 1.3e-46 158.5 0.1 6.4e-45 153.0 0.0 3.4 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 EEQ31726.1 - 2e-45 155.2 0.0 3.4e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EEQ31726.1 - 1.9e-38 130.9 0.0 4.8e-38 129.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EEQ31726.1 - 6.5e-05 23.1 0.1 0.00022 21.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 EEQ31726.1 - 0.00059 19.4 0.1 0.0021 17.6 0.1 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EEQ31726.1 - 0.0028 16.6 0.0 0.0066 15.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Zn_clus PF00172.13 EEQ31727.1 - 1.5e-07 31.1 11.2 3.2e-07 30.1 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_11 PF08241.7 EEQ31728.1 - 2.3e-07 31.2 0.0 1.4e-05 25.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ31728.1 - 4e-07 29.7 0.0 8.1e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ31728.1 - 3.6e-05 22.9 0.0 6.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EEQ31728.1 - 5.1e-05 23.8 0.0 0.00046 20.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ31728.1 - 5.3e-05 23.2 0.0 0.001 19.1 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ31728.1 - 7.5e-05 23.0 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ31728.1 - 7.6e-05 23.1 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ31728.1 - 0.00044 20.0 0.0 0.0073 16.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ31728.1 - 0.00059 19.2 0.0 0.0023 17.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EEQ31728.1 - 0.044 13.4 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SnoaL_2 PF12680.2 EEQ31729.1 - 3.3e-05 24.2 0.1 6.2e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EEQ31729.1 - 0.085 12.4 0.1 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase AMP-binding PF00501.23 EEQ31730.1 - 5.1e-165 548.9 0.0 6.6e-83 278.4 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEQ31730.1 - 4.1e-72 242.5 0.0 6.5e-35 120.4 0.0 2.5 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EEQ31730.1 - 1.3e-23 83.0 0.0 5.7e-13 48.9 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ31730.1 - 8.9e-12 45.7 0.0 2.1e-05 25.3 0.0 3.4 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EEQ31730.1 - 0.013 14.0 0.0 0.034 12.5 0.0 1.6 2 0 0 2 2 2 0 Transferase family Beta-lactamase PF00144.19 EEQ31731.1 - 2.4e-46 158.2 0.0 3.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EEQ31731.1 - 0.00077 19.2 0.0 0.0055 16.5 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) GCR1_C PF12550.3 EEQ31732.1 - 3.7e-10 39.5 0.6 6.9e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes F-box PF00646.28 EEQ31733.1 - 5.9e-05 22.6 0.5 0.0046 16.5 0.0 3.4 3 0 0 3 3 3 1 F-box domain fn3 PF00041.16 EEQ31735.1 - 4.3e-11 42.8 1.0 6.1e-08 32.6 0.1 3.0 2 1 0 2 2 2 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 EEQ31735.1 - 1.7e-06 28.3 0.1 4.3e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ31735.1 - 0.0012 18.7 0.3 0.0045 16.8 0.2 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Methyltransf_16 PF10294.4 EEQ31736.1 - 1.3e-10 40.9 0.0 2.9e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase LVIVD PF08309.6 EEQ31737.1 - 3e-06 26.1 0.6 0.019 13.9 0.0 4.3 4 0 0 4 4 4 1 LVIVD repeat Beta_propel PF09826.4 EEQ31737.1 - 0.0083 14.5 0.2 2.1 6.5 0.0 2.6 1 1 0 1 1 1 1 Beta propeller domain PQQ_3 PF13570.1 EEQ31737.1 - 0.05 13.8 0.1 0.32 11.3 0.0 2.4 3 0 0 3 3 3 0 PQQ-like domain AMP-binding PF00501.23 EEQ31740.1 - 3.2e-81 272.8 0.0 4.6e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ31740.1 - 0.0025 18.7 0.1 0.0053 17.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NDT80_PhoG PF05224.7 EEQ31742.1 - 1.6e-40 139.1 0.1 2.4e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family eIF3g PF12353.3 EEQ31743.1 - 1.3e-47 160.9 1.8 2.2e-47 160.1 1.3 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EEQ31743.1 - 2.8e-16 58.8 0.0 4.6e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31743.1 - 2.3e-12 46.7 0.1 4e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ31743.1 - 2.6e-07 30.3 0.0 5.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NMO PF03060.10 EEQ31744.1 - 4.4e-72 243.0 0.9 5.2e-72 242.7 0.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEQ31744.1 - 7.2e-08 31.6 0.0 6.8e-07 28.4 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEQ31744.1 - 3e-07 29.6 1.8 5e-07 28.8 1.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EEQ31744.1 - 0.0019 17.2 0.2 0.0031 16.5 0.2 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EEQ31744.1 - 0.013 14.4 0.2 0.02 13.8 0.1 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase TipAS PF07739.8 EEQ31744.1 - 0.17 12.2 0.2 0.28 11.4 0.1 1.3 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Pterin_bind PF00809.17 EEQ31745.1 - 3.8e-65 219.1 0.0 6.3e-65 218.4 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EEQ31745.1 - 4.7e-39 133.0 0.0 7.7e-39 132.3 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ArfGap PF01412.13 EEQ31746.1 - 9.2e-36 122.1 0.6 1.6e-35 121.3 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.6 EEQ31747.1 - 1.1e-40 138.6 0.0 1.4e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EEQ31747.1 - 6.8e-08 32.0 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 GHL1-3 PF11308.3 EEQ31747.1 - 0.065 12.5 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 NP1-WLL PF11733.3 EEQ31747.1 - 0.096 12.9 1.5 8.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Non-capsid protein NP1 MR_MLE_C PF13378.1 EEQ31748.1 - 1.9e-18 66.4 0.0 5.8e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EEQ31748.1 - 4.9e-15 55.7 0.2 4.2e-13 49.6 0.0 2.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EEQ31748.1 - 9.4e-08 32.0 0.1 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EEQ31748.1 - 0.046 12.6 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus PepSY PF03413.14 EEQ31748.1 - 0.13 12.9 0.1 0.44 11.2 0.1 1.9 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Aminotran_5 PF00266.14 EEQ31749.1 - 4.7e-30 104.5 0.0 6.7e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PWI PF01480.12 EEQ31750.1 - 1.5e-11 44.2 0.3 4.3e-11 42.7 0.2 1.8 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EEQ31750.1 - 0.03 13.9 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1929 PF09118.6 EEQ31751.1 - 0.057 13.5 0.3 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) NPCBM_assoc PF10633.4 EEQ31751.1 - 0.057 13.4 0.5 0.29 11.1 0.4 2.1 1 1 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Herpes_capsid PF06112.6 EEQ31752.1 - 3.2 7.7 8.1 21 5.1 5.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein PGI PF00342.14 EEQ31753.1 - 9.5e-218 723.4 1.5 1.1e-217 723.2 1.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_S21 PF01165.15 EEQ31754.1 - 2.8e-10 39.4 3.1 5e-10 38.6 2.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Leu_Phe_trans PF03588.9 EEQ31754.1 - 0.017 14.3 0.3 0.026 13.6 0.2 1.4 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase Rhodanese PF00581.15 EEQ31755.1 - 9.5e-11 42.0 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_28 PF02636.12 EEQ31756.1 - 5.7e-79 265.0 0.0 7.1e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RRM_1 PF00076.17 EEQ31759.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31759.1 - 0.0041 17.0 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ31759.1 - 0.0054 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gypsy PF07253.6 EEQ31760.1 - 0.019 13.3 0.0 0.031 12.6 0.0 1.3 1 0 0 1 1 1 0 Gypsy protein HSP70 PF00012.15 EEQ31761.1 - 9.6e-262 869.2 15.1 1.1e-261 869.0 10.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ31761.1 - 5.6e-15 54.7 6.6 3.8e-13 48.7 1.7 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EEQ31761.1 - 0.00021 20.9 0.1 0.00055 19.5 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EEQ31761.1 - 0.00046 20.0 6.3 2.5 7.9 2.0 4.6 1 1 1 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 EEQ31761.1 - 0.071 12.2 3.9 1.9 7.5 0.3 3.3 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase DUF2415 PF10313.4 EEQ31762.1 - 4e-16 58.4 0.0 1e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EEQ31762.1 - 0.031 14.1 0.8 6.7 6.7 0.3 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat CAP_N PF01213.14 EEQ31762.1 - 3 7.0 7.4 5.6 6.1 5.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DctQ PF04290.7 EEQ31763.1 - 2.7 7.7 16.0 0.92 9.2 4.1 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DSHCT PF08148.7 EEQ31764.1 - 1.1e-60 204.0 0.6 2.2e-60 202.9 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EEQ31764.1 - 8.9e-19 67.6 0.0 2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ31764.1 - 2.8e-06 27.0 0.0 6.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ31764.1 - 0.12 12.1 0.0 2.2 8.0 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit IBN_N PF03810.14 EEQ31765.1 - 8.2e-14 51.2 0.3 2.7e-11 43.2 0.0 4.4 6 0 0 6 6 6 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EEQ31765.1 - 1.5e-07 31.5 0.1 0.0061 16.8 0.0 2.9 2 0 0 2 2 2 2 HEAT repeats Cse1 PF08506.5 EEQ31765.1 - 9e-07 27.7 0.0 1.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 EEQ31765.1 - 0.00013 21.8 1.8 0.007 16.2 0.0 3.7 3 1 0 3 3 3 1 Exportin 1-like protein DUF2435 PF10363.4 EEQ31765.1 - 0.0018 18.1 0.2 0.0095 15.8 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) GRIP PF01465.15 EEQ31765.1 - 0.051 13.0 0.1 0.73 9.3 0.0 3.1 1 1 1 2 2 2 0 GRIP domain HEAT PF02985.17 EEQ31765.1 - 0.13 12.4 0.6 2.8 8.2 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 EEQ31765.1 - 0.16 12.5 2.8 3.1 8.4 0.0 4.5 5 0 0 5 5 5 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ31765.1 - 0.16 12.3 1.1 1.6 9.1 0.0 3.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RRM_1 PF00076.17 EEQ31767.1 - 1.4e-08 34.2 0.0 3.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31767.1 - 7.1e-07 29.1 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ31767.1 - 0.0035 17.0 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CENP-F_N PF10481.4 EEQ31768.1 - 0.12 11.6 4.0 0.21 10.9 2.8 1.7 1 1 0 1 1 1 0 Cenp-F N-terminal domain Phage_lysis PF03245.8 EEQ31768.1 - 0.22 11.5 2.6 0.28 11.1 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein PV-1 PF06637.6 EEQ31768.1 - 0.22 10.0 5.4 0.19 10.2 2.1 1.8 2 0 0 2 2 2 0 PV-1 protein (PLVAP) DivIC PF04977.10 EEQ31768.1 - 0.3 10.6 3.0 0.28 10.6 0.3 1.9 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 EEQ31768.1 - 0.33 11.3 3.5 13 6.2 0.2 2.6 2 0 0 2 2 2 0 SlyX ATG16 PF08614.6 EEQ31768.1 - 0.87 9.3 8.1 0.1 12.4 0.4 2.4 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) FAM176 PF14851.1 EEQ31769.1 - 0.87 9.2 6.5 3.3 7.3 0.4 3.2 2 0 0 2 2 2 0 FAM176 family Peptidase_S49_N PF08496.5 EEQ31769.1 - 7.3 6.3 9.9 4.5 7.0 2.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DbpA PF03880.10 EEQ31770.1 - 0.0012 18.4 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain MIP-T3 PF10243.4 EEQ31770.1 - 1.4 7.2 23.6 2.1 6.6 16.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MFS_1 PF07690.11 EEQ31771.1 - 1.2e-22 80.1 29.4 4.5e-21 74.9 8.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ31771.1 - 2.4e-10 39.5 2.8 2.4e-10 39.5 1.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Kinetocho_Slk19 PF12709.2 EEQ31772.1 - 1.2e-21 76.5 31.1 1.1e-20 73.5 4.9 5.0 3 1 2 5 5 5 2 Central kinetochore-associated MscS_porin PF12795.2 EEQ31772.1 - 0.016 14.5 28.9 0.039 13.2 3.6 2.6 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain WEMBL PF05701.6 EEQ31772.1 - 0.017 13.6 45.6 0.078 11.4 31.6 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Fib_alpha PF08702.5 EEQ31772.1 - 0.042 13.9 14.6 1.1 9.3 1.1 4.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 EEQ31772.1 - 0.08 11.3 25.1 0.16 10.3 5.8 2.4 1 1 1 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 EEQ31772.1 - 0.082 12.7 44.6 0.041 13.7 9.7 3.4 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EEQ31772.1 - 0.88 8.6 12.0 8 5.5 0.1 3.5 1 1 3 4 4 4 0 Reovirus sigma C capsid protein DUF4200 PF13863.1 EEQ31772.1 - 0.95 9.4 37.5 0.17 11.8 11.3 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) IncA PF04156.9 EEQ31772.1 - 1.1 8.8 37.8 0.61 9.6 10.8 2.9 1 1 0 2 2 2 0 IncA protein DUF1664 PF07889.7 EEQ31772.1 - 1.3 8.8 18.6 0.68 9.7 2.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.3 EEQ31772.1 - 2.5 7.2 29.7 0.67 9.1 2.5 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Filament PF00038.16 EEQ31772.1 - 3.1 7.1 42.3 0.61 9.4 23.8 3.2 2 1 0 2 2 2 0 Intermediate filament protein DUF745 PF05335.8 EEQ31772.1 - 3.1 7.2 32.2 0.066 12.7 10.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Tropomyosin PF00261.15 EEQ31772.1 - 5 6.1 47.8 17 4.4 33.2 2.0 1 1 0 1 1 1 0 Tropomyosin Lectin_N PF03954.9 EEQ31772.1 - 6 6.2 9.8 7.5 5.9 0.3 3.1 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF4201 PF13870.1 EEQ31772.1 - 6.5 6.1 27.9 4.6 6.6 5.9 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) CALCOCO1 PF07888.6 EEQ31772.1 - 8.4 4.5 35.7 2.8 6.1 8.7 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FAD_binding_3 PF01494.14 EEQ31773.1 - 6.7e-07 28.6 0.2 7.6e-06 25.2 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EEQ31773.1 - 9e-05 22.4 1.2 0.0026 17.7 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ31773.1 - 0.00015 20.7 0.1 0.00044 19.2 0.1 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEQ31773.1 - 0.053 13.2 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding TUDOR PF00567.19 EEQ31774.1 - 0.00091 19.0 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Tudor domain Fungal_trans PF04082.13 EEQ31775.1 - 2.1e-36 125.1 0.4 4.7e-36 123.9 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ31775.1 - 0.0038 17.1 18.0 0.0067 16.3 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sof1 PF04158.9 EEQ31775.1 - 0.027 14.5 0.7 0.077 13.0 0.5 1.7 1 0 0 1 1 1 0 Sof1-like domain MFS_1 PF07690.11 EEQ31776.1 - 6.1e-14 51.4 32.3 6.1e-14 51.4 22.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEQ31776.1 - 1.3e-10 40.9 4.1 1.3e-10 40.9 2.8 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Amidohydro_4 PF13147.1 EEQ31777.1 - 4e-15 56.6 0.2 1.5e-13 51.4 0.1 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EEQ31777.1 - 5.8e-13 49.1 0.0 8.3e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EEQ31777.1 - 9.7e-07 28.3 0.1 5.6e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EEQ31777.1 - 3.6e-06 26.6 0.1 1.3e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase GMC_oxred_N PF00732.14 EEQ31778.1 - 1.1e-51 175.7 0.0 1.4e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ31778.1 - 5.2e-37 127.3 0.0 7.9e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EEQ31778.1 - 4.9e-07 28.9 0.0 0.00018 20.5 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ31778.1 - 2.6e-05 23.2 0.0 0.082 11.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEQ31778.1 - 9e-05 22.4 0.1 0.00029 20.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEQ31778.1 - 9.1e-05 21.5 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EEQ31778.1 - 0.01 14.5 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 EEQ31778.1 - 0.011 14.8 0.1 0.16 10.9 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ31778.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ31778.1 - 0.091 13.1 0.2 0.92 9.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.17 EEQ31779.1 - 6.9e-161 535.6 0.3 8.2e-161 535.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4538 PF15061.1 EEQ31779.1 - 0.13 11.6 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Glucosamine_iso PF01182.15 EEQ31780.1 - 5.7e-14 52.3 0.0 8.4e-13 48.4 0.0 2.1 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.16 EEQ31781.1 - 4.1e-60 203.2 0.0 6e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EEQ31781.1 - 5e-05 23.2 0.0 0.00018 21.4 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ31781.1 - 0.00083 19.4 0.0 0.0024 18.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 EEQ31781.1 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_10 PF13673.1 EEQ31781.1 - 0.016 15.3 0.0 0.047 13.7 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.7 EEQ31782.1 - 3e-40 138.2 0.0 3e-40 138.2 0.0 1.8 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family MalF_P2 PF14785.1 EEQ31782.1 - 0.015 15.2 0.9 0.038 13.8 0.7 1.6 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Hexokinase_2 PF03727.11 EEQ31783.1 - 2.9e-30 105.2 0.0 1e-24 87.0 0.0 2.3 1 1 1 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EEQ31783.1 - 8.2e-30 103.6 0.0 1.6e-29 102.7 0.0 1.4 1 1 0 1 1 1 1 Hexokinase HNH_2 PF13391.1 EEQ31784.1 - 2.9e-10 39.7 0.0 9.9e-10 38.0 0.0 2.0 1 1 0 1 1 1 1 HNH endonuclease BNIP2 PF12496.3 EEQ31784.1 - 0.27 11.3 3.5 0.088 12.9 0.2 1.9 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 p450 PF00067.17 EEQ31785.1 - 1.8e-43 148.7 0.0 2.7e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Hep_59 PF07052.6 EEQ31786.1 - 6.4e-20 71.4 0.1 6.4e-20 71.4 0.0 2.6 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 TRP PF06011.7 EEQ31787.1 - 6.5e-132 440.2 9.8 8.4e-132 439.8 6.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEQ31787.1 - 6.3e-35 120.2 0.1 1e-34 119.5 0.1 1.4 1 0 0 1 1 1 1 ML-like domain TFIIIC_sub6 PF10419.4 EEQ31788.1 - 1.5e-16 59.5 0.1 2.4e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 TFIIIC subunit ELFV_dehydrog PF00208.16 EEQ31789.1 - 5.4e-56 189.8 0.0 8.6e-56 189.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EEQ31789.1 - 1.9e-22 78.6 0.1 2.3e-15 55.2 0.0 2.5 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EEQ31789.1 - 0.075 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain MFS_1 PF07690.11 EEQ31790.1 - 1.5e-23 83.0 30.6 1e-10 40.8 5.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Fun_ATP-synt_8 PF05933.8 EEQ31790.1 - 0.79 9.7 3.8 14 5.8 0.1 3.5 3 0 0 3 3 3 0 Fungal ATP synthase protein 8 (A6L) DUF2919 PF11143.3 EEQ31790.1 - 1.2 8.9 7.1 1.1 9.0 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) Myb_DNA-bind_6 PF13921.1 EEQ31794.1 - 4.2e-30 103.6 5.0 2.1e-14 53.3 1.2 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ31794.1 - 1.8e-27 95.1 7.6 1.4e-09 37.8 0.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EEQ31794.1 - 0.17 11.7 4.1 4.3 7.2 0.2 2.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PPR_3 PF13812.1 EEQ31795.1 - 2.3e-13 49.2 1.5 0.0012 18.9 0.0 7.6 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEQ31795.1 - 1.1e-10 41.3 1.6 0.015 15.2 0.0 6.6 5 2 2 7 7 7 3 PPR repeat family PPR PF01535.15 EEQ31795.1 - 5.3e-05 22.9 2.7 26 5.0 0.0 6.5 6 0 0 6 6 6 1 PPR repeat Terminase_4 PF05119.7 EEQ31795.1 - 0.052 13.7 0.0 0.25 11.5 0.0 2.1 1 0 0 1 1 1 0 Phage terminase, small subunit Ribosomal_S18 PF01084.15 EEQ31796.1 - 1.2e-15 57.0 0.0 2.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 VIT1 PF01988.14 EEQ31796.1 - 0.055 12.9 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 VIT family WD40 PF00400.27 EEQ31797.1 - 1.9e-50 167.0 27.7 1.1e-07 31.4 0.1 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat IRF PF00605.12 EEQ31797.1 - 0.018 14.8 0.5 5.7 6.7 0.1 2.6 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Peptidase_M36 PF02128.10 EEQ31801.1 - 1.7e-158 527.3 8.5 2.1e-158 527.0 5.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EEQ31801.1 - 2.9e-13 49.0 2.2 6.4e-13 47.9 1.5 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EEQ31801.1 - 0.00023 20.9 0.2 0.0009 19.0 0.0 2.1 3 0 0 3 3 3 1 Thermolysin metallopeptidase, alpha-helical domain IclR PF01614.13 EEQ31803.1 - 0.029 14.0 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial transcriptional regulator Methyltransf_25 PF13649.1 EEQ31804.1 - 2.5e-10 40.6 0.0 4.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ31804.1 - 8.2e-09 36.0 0.2 2e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ31804.1 - 2.2e-08 33.8 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ31804.1 - 1.3e-06 28.7 0.0 2.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ31804.1 - 2.8e-05 23.8 0.1 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ31804.1 - 0.00024 21.5 0.0 0.00049 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ31804.1 - 0.00031 20.7 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ31804.1 - 0.049 12.6 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Alk_phosphatase PF00245.15 EEQ31806.1 - 6.3e-108 361.1 0.0 7.4e-108 360.9 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EEQ31806.1 - 4.8e-06 26.1 0.1 8.9e-05 21.9 0.0 2.5 3 0 0 3 3 3 1 Metalloenzyme superfamily FUSC_2 PF13515.1 EEQ31807.1 - 3e-29 101.5 9.2 3e-29 101.5 6.4 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 EEQ31807.1 - 2.2e-05 23.3 14.0 0.0021 16.7 0.0 3.8 3 1 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 EEQ31807.1 - 0.07 11.5 17.2 0.22 9.9 9.7 3.1 2 1 0 2 2 2 0 Fusaric acid resistance protein family DUF2421 PF10334.4 EEQ31807.1 - 0.1 12.1 0.4 0.21 11.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) APH PF01636.18 EEQ31808.1 - 6.5e-17 62.0 0.8 1.2e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEQ31808.1 - 0.0049 15.8 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.15 EEQ31808.1 - 0.03 13.8 0.2 0.085 12.4 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EEQ31808.1 - 0.047 12.7 0.0 0.098 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Oxidored_molyb PF00174.14 EEQ31809.1 - 4e-41 140.2 0.0 7.8e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EEQ31809.1 - 1.5e-38 131.3 0.2 3e-38 130.4 0.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 EEQ31809.1 - 6.2e-25 87.8 0.0 7.7e-24 84.3 0.0 2.9 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EEQ31809.1 - 4.7e-17 61.5 0.5 1.4e-16 59.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 EEQ31809.1 - 1.2e-15 57.4 0.0 2.5e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEQ31809.1 - 0.00043 20.2 0.2 0.035 13.9 0.0 3.3 3 1 1 4 4 4 1 Ferric reductase NAD binding domain UPF0270 PF06794.7 EEQ31809.1 - 0.042 13.6 0.2 0.099 12.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) HTH_38 PF13936.1 EEQ31809.1 - 0.061 12.8 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Beta-lactamase PF00144.19 EEQ31810.1 - 5.8e-23 81.4 1.7 1.1e-22 80.5 1.2 1.3 1 1 0 1 1 1 1 Beta-lactamase HNH_2 PF13391.1 EEQ31811.1 - 5.8e-11 42.0 0.0 1.5e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease zf-rbx1 PF12678.2 EEQ31812.1 - 2.5e-07 30.6 5.2 5.2e-07 29.6 3.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEQ31812.1 - 1.2e-05 25.0 14.3 0.00011 21.9 10.0 2.2 1 1 1 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EEQ31812.1 - 6.6e-05 22.6 4.5 6.6e-05 22.6 3.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EEQ31812.1 - 0.15 11.7 5.1 0.4 10.3 3.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EEQ31812.1 - 0.15 12.0 5.9 0.46 10.4 4.1 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 EEQ31812.1 - 0.25 11.3 11.8 3.9 7.5 8.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ31812.1 - 2.3 7.9 11.7 12 5.6 7.9 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ31812.1 - 8.5 6.1 9.6 34 4.2 0.3 2.1 1 1 1 2 2 2 0 zinc-RING finger domain E1-E2_ATPase PF00122.15 EEQ31813.1 - 4.1e-12 45.6 0.0 9.9e-12 44.3 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EEQ31813.1 - 7e-12 45.1 0.0 2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ31813.1 - 1.9e-11 44.4 0.1 6.4e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ31813.1 - 1.1e-09 39.0 6.1 2e-08 34.9 4.2 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ31813.1 - 0.036 13.6 0.4 0.1 12.1 0.3 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PuR_N PF09182.5 EEQ31814.1 - 0.067 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Ank_2 PF12796.2 EEQ31815.1 - 3.3e-18 65.8 0.3 9.7e-05 22.6 0.0 6.1 4 3 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ31815.1 - 2.8e-16 59.5 3.2 0.0066 16.9 0.0 7.4 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ31815.1 - 1.5e-15 56.8 4.8 0.0077 16.4 0.0 7.5 7 1 0 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 EEQ31815.1 - 9.8e-14 50.3 6.1 0.45 10.4 0.0 7.0 6 2 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EEQ31815.1 - 4.6e-12 44.9 3.5 0.057 13.6 0.0 7.5 7 0 0 7 7 7 3 Ankyrin repeat LysM PF01476.15 EEQ31816.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 LysM domain HSDR_N_2 PF13588.1 EEQ31817.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) RicinB_lectin_2 PF14200.1 EEQ31820.1 - 1.1e-05 25.7 0.2 0.0016 18.8 0.1 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like BA14K PF07886.6 EEQ31820.1 - 0.26 10.9 0.3 0.26 10.9 0.2 2.3 3 0 0 3 3 3 0 BA14K-like protein Ank_4 PF13637.1 EEQ31822.1 - 1.5e-12 47.6 0.1 9.8e-09 35.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ31822.1 - 7.1e-12 45.5 0.0 1.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ31822.1 - 5.4e-10 38.5 0.0 0.0056 16.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EEQ31822.1 - 1.4e-07 31.0 0.0 0.038 14.2 0.0 3.2 3 0 0 3 3 2 2 Ankyrin repeat AAA_16 PF13191.1 EEQ31822.1 - 8.2e-07 29.1 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EEQ31822.1 - 6.2e-06 25.9 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EEQ31822.1 - 9.1e-06 25.8 0.0 2.6e-05 24.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain Ank_5 PF13857.1 EEQ31822.1 - 1.6e-05 24.9 0.1 0.0067 16.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NB-ARC PF00931.17 EEQ31822.1 - 0.023 13.5 0.0 0.42 9.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 EEQ31822.1 - 0.026 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ31822.1 - 0.042 14.6 0.0 0.19 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EEQ31822.1 - 0.052 13.0 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EEQ31822.1 - 0.085 13.1 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEQ31822.1 - 0.092 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 EEQ31822.1 - 0.12 11.3 0.0 0.54 9.1 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.13 EEQ31822.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 EEQ31822.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SE PF00437.15 EEQ31822.1 - 0.25 10.1 0.0 0.41 9.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein GPAT_N PF14829.1 EEQ31823.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 1 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Glyco_hydro_18 PF00704.23 EEQ31825.1 - 1e-46 160.0 0.9 1.4e-46 159.5 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 EEQ31825.1 - 5.2e-30 103.2 0.9 1.6e-29 101.6 0.6 1.9 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 EEQ31825.1 - 2.8e-06 27.0 0.6 0.096 12.5 0.1 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EEQ31825.1 - 0.00034 20.5 3.9 0.00034 20.5 2.7 3.9 3 0 0 3 3 3 1 Chitin recognition protein LysM PF01476.15 EEQ31827.1 - 4.5e-19 68.0 0.9 9.9e-05 22.1 0.0 3.2 3 0 0 3 3 3 3 LysM domain MGC-24 PF05283.6 EEQ31827.1 - 0.45 10.2 7.2 0.85 9.3 5.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Rubella_E2 PF05749.6 EEQ31827.1 - 1.3 8.2 7.2 0.5 9.5 2.1 2.3 2 1 1 3 3 3 0 Rubella membrane glycoprotein E2 SAGA-Tad1 PF12767.2 EEQ31828.1 - 3.5e-61 207.0 0.0 5e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.7 EEQ31829.1 - 4.9e-53 179.0 6.2 4.9e-53 179.0 4.3 2.0 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EEQ31829.1 - 1.2e-24 84.4 17.2 0.034 14.7 0.0 12.3 7 4 7 14 14 12 7 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ31829.1 - 8e-19 67.7 2.9 0.0063 16.8 0.1 8.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ31829.1 - 3.3e-13 49.9 9.7 0.044 14.4 0.1 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ31829.1 - 1.3e-12 47.1 3.3 0.003 17.1 0.1 7.5 5 2 2 7 7 7 2 TPR repeat TPR_2 PF07719.12 EEQ31829.1 - 7.3e-12 44.2 2.3 0.1 12.5 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat NARP1 PF12569.3 EEQ31829.1 - 2.7e-05 23.1 5.4 0.025 13.3 0.0 4.7 3 1 1 5 5 5 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.1 EEQ31829.1 - 2.9e-05 23.5 0.3 0.74 9.7 0.2 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ31829.1 - 9.3e-05 21.8 2.0 0.43 10.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ31829.1 - 0.00014 21.7 1.4 5.6 6.9 0.0 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ31829.1 - 0.00045 20.1 0.4 4.3 7.7 0.0 6.3 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ31829.1 - 0.024 14.4 1.3 24 5.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RrnaAD PF00398.15 EEQ31830.1 - 6.5e-59 199.0 0.0 8.8e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EEQ31830.1 - 2.3e-10 40.5 0.0 4.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ31830.1 - 7.2e-07 29.7 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ31830.1 - 3.8e-05 23.1 0.0 6.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EEQ31830.1 - 4.5e-05 23.8 0.0 9.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ31830.1 - 7e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EEQ31830.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEQ31830.1 - 0.00023 20.3 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EEQ31830.1 - 0.0005 19.3 0.0 0.00097 18.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EEQ31830.1 - 0.00052 19.7 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ31830.1 - 0.0021 18.5 0.0 0.0067 16.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Met_10 PF02475.11 EEQ31830.1 - 0.0052 16.4 0.3 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein PrmA PF06325.8 EEQ31830.1 - 0.01 15.0 0.7 0.035 13.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EEQ31830.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EEQ31830.1 - 0.03 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 EEQ31830.1 - 0.038 12.8 0.0 0.069 12.0 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_25 PF13649.1 EEQ31830.1 - 0.049 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.13 EEQ31831.1 - 3.9e-48 163.7 0.0 9.5e-48 162.4 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 EEQ31833.1 - 2.9e-35 119.7 0.4 2.7e-16 58.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31833.1 - 1.1e-26 92.5 0.1 2.3e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ31833.1 - 2.6e-10 40.0 0.1 0.00066 19.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEQ31833.1 - 0.0022 17.8 0.1 3.1 7.6 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif MCRS_N PF13325.1 EEQ31833.1 - 0.15 11.5 1.7 0.29 10.5 1.2 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Med15 PF09606.5 EEQ31833.1 - 0.5 8.5 83.6 0.72 7.9 58.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cupin_8 PF13621.1 EEQ31834.1 - 2.3e-09 37.1 0.0 4.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EEQ31834.1 - 4.6e-09 36.5 0.0 4.9e-08 33.1 0.0 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EEQ31834.1 - 1.1e-07 31.3 9.0 1.1e-07 31.3 6.3 2.5 3 0 0 3 3 3 1 PHD-finger Zn_clus PF00172.13 EEQ31834.1 - 1.9 8.4 28.1 0.042 13.7 3.2 3.2 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EEQ31834.1 - 2 8.6 13.7 0.58 10.3 1.3 3.1 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region PHD_2 PF13831.1 EEQ31834.1 - 4.2 6.7 10.9 4.3 6.7 6.0 2.3 2 0 0 2 2 2 0 PHD-finger COG4 PF08318.7 EEQ31836.1 - 1.7e-100 336.0 0.0 2.2e-100 335.6 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein Prominin PF05478.6 EEQ31836.1 - 0.11 10.0 0.8 0.2 9.1 0.6 1.3 1 0 0 1 1 1 0 Prominin SIR2 PF02146.12 EEQ31837.1 - 1.5e-57 194.2 0.0 2.6e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Hexokinase_2 PF03727.11 EEQ31838.1 - 6.1e-86 287.5 0.0 8.5e-86 287.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EEQ31838.1 - 1.1e-75 253.5 0.0 1.5e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase WD40 PF00400.27 EEQ31839.1 - 0.00017 21.2 1.4 3.1 7.8 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEQ31839.1 - 0.15 10.7 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like DUF3661 PF12400.3 EEQ31840.1 - 7.9e-39 132.6 6.0 1.1e-38 132.2 4.1 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein RRM_1 PF00076.17 EEQ31841.1 - 5.8e-08 32.2 0.4 2.5e-07 30.2 0.2 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ31841.1 - 6.9e-06 25.8 0.1 1.1e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31841.1 - 9e-06 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ammonium_transp PF00909.16 EEQ31842.1 - 1.2e-114 382.9 27.7 1.4e-114 382.6 19.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.15 EEQ31843.1 - 2.4e-79 265.5 0.1 4.4e-79 264.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ31843.1 - 3.8e-39 134.0 0.5 3.8e-39 134.0 0.4 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ31843.1 - 1.4e-30 107.3 0.1 2.6e-29 103.1 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ31843.1 - 1.5e-21 75.5 0.0 3.6e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEQ31843.1 - 1.3e-16 61.3 0.0 4.1e-16 59.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ31843.1 - 1.4e-13 50.6 0.0 3.8e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ31843.1 - 4.3e-06 26.5 1.4 0.00018 21.2 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Man-6-P_recep PF02157.10 EEQ31843.1 - 0.065 12.2 0.3 0.36 9.7 0.2 2.0 2 0 0 2 2 2 0 Mannose-6-phosphate receptor Rad21_Rec8_N PF04825.8 EEQ31844.1 - 3e-39 133.4 0.0 5.2e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EEQ31844.1 - 7.8e-07 28.1 0.2 1.8e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EEQ31844.1 - 0.0038 16.8 0.1 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 ScpA/B protein Neur_chan_memb PF02932.11 EEQ31845.1 - 0.14 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cbl_N3 PF02762.9 EEQ31845.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Ank_2 PF12796.2 EEQ31846.1 - 8.4e-83 272.8 19.0 7.5e-18 64.6 0.2 6.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ31846.1 - 3.9e-65 212.6 18.4 1.3e-09 37.3 0.2 11.3 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 EEQ31846.1 - 4e-57 188.9 6.5 3.5e-10 39.7 0.1 8.8 3 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ31846.1 - 1.4e-50 168.8 7.3 2.6e-08 34.1 0.0 9.1 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ31846.1 - 4.8e-45 147.0 10.2 3.6e-05 23.5 0.0 11.6 11 0 0 11 11 11 9 Ankyrin repeat zf-C2H2_4 PF13894.1 EEQ31846.1 - 2.7 8.5 10.0 36 5.0 1.2 4.2 3 1 1 4 4 4 0 C2H2-type zinc finger DUF3442 PF11924.3 EEQ31847.1 - 0.14 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3442) APH PF01636.18 EEQ31848.1 - 2.3e-09 37.3 0.5 4.6e-08 33.0 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ31848.1 - 0.034 12.7 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Nterm_IS4 PF13006.2 EEQ31849.1 - 0.06 13.3 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Peptidase_S8 PF00082.17 EEQ31850.1 - 6.7e-19 68.1 0.0 1.6e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Subtilase family AAA_12 PF13087.1 EEQ31851.1 - 1.2e-42 145.5 0.1 2.6e-42 144.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EEQ31851.1 - 2.9e-23 82.6 0.0 6.2e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ31851.1 - 1.9e-05 24.2 0.0 5.7e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ31851.1 - 2.4e-05 23.9 0.0 0.0053 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EEQ31851.1 - 0.00029 19.9 0.0 0.0056 15.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EEQ31851.1 - 0.0018 17.7 0.0 0.005 16.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EEQ31851.1 - 0.0037 17.1 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EEQ31851.1 - 0.017 14.8 0.0 0.059 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEQ31851.1 - 0.018 15.8 0.1 0.7 10.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 EEQ31851.1 - 0.059 13.0 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 Helicase Mg_chelatase PF01078.16 EEQ31851.1 - 0.071 12.2 0.6 0.17 11.0 0.0 1.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATP-grasp_4 PF13535.1 EEQ31852.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Zn_clus PF00172.13 EEQ31855.1 - 0.003 17.4 9.0 0.003 17.4 6.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EEQ31855.1 - 0.024 14.4 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.12 EEQ31856.1 - 5.5e-33 113.5 0.0 7.5e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase DUF221 PF02714.10 EEQ31857.1 - 4.4e-108 360.9 29.1 4.4e-108 360.9 20.2 1.8 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEQ31857.1 - 5.5e-46 155.9 1.7 5.5e-46 155.9 1.2 3.2 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EEQ31857.1 - 4.3e-14 52.1 0.9 1.2e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EEQ31857.1 - 2.1e-10 40.9 5.2 0.00043 20.7 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) AAA_13 PF13166.1 EEQ31857.1 - 0.16 10.3 4.8 0.028 12.8 0.6 1.6 2 0 0 2 2 2 0 AAA domain SnoaL_2 PF12680.2 EEQ31858.1 - 3.8e-07 30.4 0.0 7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EEQ31858.1 - 1.7e-05 24.4 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.13 EEQ31858.1 - 0.049 12.9 0.1 0.99 8.6 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Indigoidine_A PF04227.7 EEQ31859.1 - 1.2e-100 336.5 1.7 8.2e-100 333.8 1.2 2.0 1 1 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EEQ31859.1 - 2e-12 46.8 0.2 9.7e-06 24.9 0.0 3.2 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.9 EEQ31860.1 - 3.7e-140 467.2 0.0 4.2e-140 467.0 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I VTC PF09359.5 EEQ31861.1 - 1.3e-101 339.3 0.4 2.3e-101 338.5 0.3 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EEQ31861.1 - 1.2e-25 90.9 4.1 8.6e-23 81.4 2.9 3.0 1 1 0 1 1 1 1 SPX domain DUF202 PF02656.10 EEQ31861.1 - 9.9e-11 41.7 3.3 9.9e-11 41.7 2.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MCM PF00493.18 EEQ31862.1 - 1e-139 464.9 0.0 1.4e-139 464.5 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEQ31862.1 - 1.7e-25 89.8 0.0 8.8e-25 87.5 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ31862.1 - 7.3e-06 25.2 0.0 0.00025 20.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ31862.1 - 3e-05 23.7 0.2 0.00012 21.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEQ31862.1 - 0.0023 17.5 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 EEQ31862.1 - 0.2 10.2 4.2 0.038 12.6 0.3 1.6 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EEQ31863.1 - 2.9e-09 37.1 0.1 0.0013 18.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ31863.1 - 0.014 15.1 0.0 0.043 13.6 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 EEQ31863.1 - 0.017 15.6 0.0 11 6.7 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF3632 PF12311.3 EEQ31865.1 - 8.3e-06 25.7 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Band_7 PF01145.20 EEQ31867.1 - 3.9e-24 85.5 3.3 5.6e-24 85.0 2.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 EEQ31867.1 - 0.13 11.5 2.6 0.18 11.0 1.8 1.3 1 1 0 1 1 1 0 MraW methylase family CSTF2_hinge PF14327.1 EEQ31868.1 - 5.5e-30 103.2 2.5 5.5e-30 103.2 1.8 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EEQ31868.1 - 1.3e-19 69.6 0.0 2.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ31868.1 - 3.6e-16 58.9 0.0 6.2e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EEQ31868.1 - 5.5e-14 51.1 3.9 5.5e-14 51.1 2.7 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 EEQ31868.1 - 2.6e-07 30.3 0.0 4.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EEQ31868.1 - 0.02 14.3 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 SWI-SNF_Ssr4 PF08549.5 EEQ31868.1 - 1.3 7.2 10.0 1.8 6.7 7.0 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DNA_methylase PF00145.12 EEQ31869.1 - 6.1e-17 61.7 0.0 1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase SNF2_N PF00176.18 EEQ31869.1 - 1e-15 57.3 0.0 5.2e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ31869.1 - 0.0014 18.4 0.0 0.0057 16.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain IFT57 PF10498.4 EEQ31869.1 - 0.015 14.0 0.9 0.027 13.2 0.6 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 zf-piccolo PF05715.8 EEQ31869.1 - 0.024 14.6 2.1 0.078 13.0 1.5 1.8 1 0 0 1 1 1 0 Piccolo Zn-finger DUF4617 PF15395.1 EEQ31869.1 - 1.2 7.0 3.7 1.8 6.5 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) 2Fe-2S_thioredx PF01257.14 EEQ31870.1 - 7.6e-55 184.4 0.0 9.7e-55 184.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF4139 PF13598.1 EEQ31871.1 - 9.7e-49 166.3 8.3 4e-35 121.6 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EEQ31871.1 - 1.9e-11 44.3 7.6 3.4e-11 43.5 0.0 3.0 2 2 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF869 PF05911.6 EEQ31871.1 - 0.034 12.3 8.9 0.049 11.8 6.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Peptidase_C57 PF03290.8 EEQ31871.1 - 0.054 12.0 0.3 0.079 11.4 0.2 1.1 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase DUF724 PF05266.9 EEQ31871.1 - 0.097 12.2 7.5 0.076 12.6 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Nucleoplasmin PF03066.10 EEQ31871.1 - 0.29 10.6 12.4 2.6 7.5 4.4 3.2 2 1 0 2 2 2 0 Nucleoplasmin OmpH PF03938.9 EEQ31871.1 - 0.53 10.2 11.2 0.99 9.3 7.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sec34 PF04136.10 EEQ31871.1 - 1.1 8.9 6.1 4.7 6.9 1.7 2.3 1 1 1 2 2 2 0 Sec34-like family TPR_MLP1_2 PF07926.7 EEQ31871.1 - 1.3 8.7 12.1 3.6 7.3 8.4 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Abhydrolase_2 PF02230.11 EEQ31872.1 - 9.9e-20 70.9 0.0 7.9e-14 51.6 0.0 3.6 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Sua5_yciO_yrdC PF01300.13 EEQ31873.1 - 8.8e-55 184.7 0.2 1.8e-54 183.7 0.0 1.5 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 EEQ31873.1 - 2.8e-25 88.8 0.0 6.8e-25 87.5 0.0 1.7 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding FbpA PF05833.6 EEQ31874.1 - 1.5e-37 129.2 4.9 1.5e-37 129.2 3.4 1.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 EEQ31874.1 - 1.1e-33 115.1 1.7 1.9e-33 114.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 EEQ31874.1 - 9.5e-16 57.4 0.0 3e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Clat_adaptor_s PF01217.15 EEQ31875.1 - 1.8e-13 50.4 0.0 3.6e-12 46.2 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain TSC22 PF01166.13 EEQ31876.1 - 0.097 12.6 2.5 0.25 11.3 1.7 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.7 EEQ31877.1 - 0.00067 19.4 15.8 0.00067 19.4 10.9 3.1 3 0 0 3 3 3 2 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 EEQ31877.1 - 0.26 11.1 4.6 0.066 13.0 0.7 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1515 PF07439.6 EEQ31877.1 - 0.28 11.0 9.0 0.095 12.5 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) HAUS6_N PF14661.1 EEQ31877.1 - 1.2 8.4 13.2 3.7 6.8 9.0 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF3573 PF12097.3 EEQ31877.1 - 1.7 7.2 4.4 1.1 7.7 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) IncA PF04156.9 EEQ31877.1 - 2.1 7.9 31.9 0.038 13.5 11.2 3.1 3 0 0 3 3 3 0 IncA protein ERM PF00769.14 EEQ31877.1 - 9 5.7 31.8 2.4 7.5 2.3 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family UPF0731 PF14982.1 EEQ31878.1 - 0.00017 21.4 0.3 0.0011 18.8 0.1 2.2 2 1 1 3 3 3 1 UPF0731 family Ribosomal_L16 PF00252.13 EEQ31880.1 - 1e-30 106.1 0.1 1.4e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e BPL_N PF09825.4 EEQ31882.1 - 1.5e-09 37.1 0.1 3e-08 32.8 0.0 2.0 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal FAD_binding_2 PF00890.19 EEQ31883.1 - 2.9e-81 273.4 0.1 3.4e-81 273.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EEQ31883.1 - 2.6e-09 36.6 2.4 1.2e-08 34.4 0.9 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EEQ31883.1 - 6.4e-09 35.1 0.2 1.7e-06 27.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ31883.1 - 1.2e-07 31.6 2.8 3.8e-07 30.0 1.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EEQ31883.1 - 4.3e-07 28.7 0.3 8.2e-07 27.8 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EEQ31883.1 - 1.7e-06 27.3 0.1 3.2e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EEQ31883.1 - 7.2e-06 26.0 0.0 4.6e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ31883.1 - 0.00021 21.3 0.2 0.00062 19.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEQ31883.1 - 0.00054 19.1 0.2 0.0028 16.7 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EEQ31883.1 - 0.065 12.1 0.4 0.1 11.4 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HAD_2 PF13419.1 EEQ31883.1 - 0.099 12.8 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GIDA PF01134.17 EEQ31883.1 - 0.12 11.1 2.0 0.19 10.5 1.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ABC_tran PF00005.22 EEQ31884.1 - 1.1e-06 28.9 0.1 2.1e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EEQ31884.1 - 0.0065 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EEQ31884.1 - 0.0076 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EEQ31884.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EEQ31884.1 - 0.039 13.4 0.1 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EEQ31884.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Methyltransf_2 PF00891.13 EEQ31885.1 - 1.7e-18 66.7 0.0 2.5e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF1341 PF07071.6 EEQ31885.1 - 0.0031 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1341) Dimerisation PF08100.6 EEQ31885.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_11 PF08241.7 EEQ31886.1 - 2.2e-28 98.6 0.0 7.5e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ31886.1 - 4.5e-21 75.2 0.0 5.2e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ31886.1 - 2.4e-20 72.6 0.0 1.6e-11 44.0 0.0 3.4 2 1 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ31886.1 - 6.1e-20 71.8 0.0 1.4e-11 44.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ31886.1 - 1.7e-18 66.7 0.0 2.2e-10 40.8 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ31886.1 - 5.5e-15 55.6 0.0 2.2e-08 34.4 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain MetW PF07021.7 EEQ31886.1 - 6.8e-11 41.8 0.0 5.7e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW CMAS PF02353.15 EEQ31886.1 - 1.2e-10 40.9 0.0 1.9e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EEQ31886.1 - 1.2e-10 41.4 0.1 8e-05 22.6 0.0 3.2 4 0 0 4 4 3 2 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ31886.1 - 4.4e-09 35.7 0.0 5.1e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family NodS PF05401.6 EEQ31886.1 - 5.5e-08 32.4 0.0 1.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.9 EEQ31886.1 - 1.9e-07 30.6 0.0 0.0001 21.7 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase small domain PrmA PF06325.8 EEQ31886.1 - 2.4e-05 23.6 0.0 0.011 14.8 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EEQ31886.1 - 2.8e-05 23.3 0.1 0.00018 20.7 0.0 2.3 3 0 0 3 3 3 1 Tellurite resistance protein TehB GidB PF02527.10 EEQ31886.1 - 0.00027 20.1 0.0 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.12 EEQ31886.1 - 0.00052 19.0 0.0 0.0089 15.0 0.0 2.6 3 0 0 3 3 3 1 NNMT/PNMT/TEMT family Methyltransf_15 PF09445.5 EEQ31886.1 - 0.0011 18.5 0.1 0.0023 17.5 0.0 1.6 2 0 0 2 2 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.15 EEQ31886.1 - 0.002 17.2 0.0 0.14 11.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 EEQ31886.1 - 0.0034 16.4 0.0 0.2 10.6 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EEQ31886.1 - 0.0094 15.4 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 EEQ31886.1 - 0.01 14.7 0.0 0.33 9.7 0.0 2.5 2 1 0 2 2 2 0 DREV methyltransferase FtsJ PF01728.14 EEQ31886.1 - 0.021 14.8 0.0 0.094 12.6 0.0 2.0 2 1 0 2 2 2 0 FtsJ-like methyltransferase Pox_MCEL PF03291.11 EEQ31886.1 - 0.03 13.1 0.0 0.15 10.9 0.0 2.1 2 1 1 3 3 3 0 mRNA capping enzyme Spermine_synth PF01564.12 EEQ31886.1 - 0.048 12.5 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Spermine/spermidine synthase FmrO PF07091.6 EEQ31886.1 - 0.058 12.3 0.0 0.37 9.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EEQ31886.1 - 0.059 13.0 0.0 0.64 9.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain TetR_N PF00440.18 EEQ31886.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family p450 PF00067.17 EEQ31887.1 - 8.7e-38 130.0 0.0 1.2e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.24 EEQ31888.1 - 3.2e-19 69.4 0.0 1.5e-18 67.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEQ31888.1 - 3.3e-05 24.1 0.0 0.00058 20.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EEQ31888.1 - 6.3e-05 22.4 0.0 0.00018 21.0 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 EEQ31888.1 - 0.00025 21.8 0.1 0.0015 19.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EEQ31888.1 - 0.00034 20.2 0.0 0.00079 19.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EEQ31888.1 - 0.0007 19.6 0.1 0.0027 17.7 0.0 2.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 EEQ31888.1 - 0.00081 19.1 0.0 0.0022 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ31888.1 - 0.0017 18.5 0.1 0.013 15.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain Zot PF05707.7 EEQ31888.1 - 0.005 16.3 0.1 0.11 11.9 0.0 2.5 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_28 PF13521.1 EEQ31888.1 - 0.031 14.2 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EEQ31888.1 - 0.043 13.7 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EEQ31888.1 - 0.044 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EEQ31888.1 - 0.045 13.3 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEQ31888.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain HNF-1_N PF04814.8 EEQ31888.1 - 0.064 13.3 0.2 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus AAA_14 PF13173.1 EEQ31888.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EEQ31888.1 - 0.14 11.2 0.0 0.58 9.2 0.0 1.9 2 0 0 2 2 2 0 KaiC T2SE PF00437.15 EEQ31888.1 - 0.16 10.8 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FA_hydroxylase PF04116.8 EEQ31889.1 - 4e-17 62.6 13.3 4e-17 62.6 9.2 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HA2 PF04408.18 EEQ31890.1 - 5.2e-17 61.7 0.1 5.2e-17 61.7 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEQ31890.1 - 5.7e-16 58.3 0.0 1.8e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEQ31890.1 - 7.3e-13 48.1 0.3 3.2e-12 46.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ31890.1 - 0.00056 19.4 0.0 0.0015 18.0 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EEQ31890.1 - 0.002 17.6 0.0 0.0052 16.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEQ31890.1 - 0.012 15.8 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEQ31890.1 - 0.08 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Zn_clus PF00172.13 EEQ31891.1 - 3.6e-09 36.3 12.2 6.5e-09 35.5 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EEQ31892.1 - 7.9e-19 68.0 2.2 1.5e-18 67.1 1.5 1.3 1 1 0 1 1 1 1 RTA1 like protein DUF3112 PF11309.3 EEQ31892.1 - 1.3 8.8 7.2 4.4 7.0 5.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) MerC PF03203.9 EEQ31892.1 - 2.2 8.6 8.4 0.87 9.9 0.2 2.4 2 1 0 2 2 2 0 MerC mercury resistance protein Fungal_lectin PF07938.7 EEQ31893.1 - 1.3e-52 178.9 2.3 5.4e-39 134.3 0.3 2.0 1 1 1 2 2 2 2 Fungal fucose-specific lectin TauD PF02668.11 EEQ31894.1 - 6.3e-25 88.3 0.0 7.9e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Complex1_LYR PF05347.10 EEQ31896.1 - 4.6e-09 35.9 0.2 6.8e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ31896.1 - 8.6e-07 29.0 0.1 1.6e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EEQ31896.1 - 3.7e-05 24.1 0.0 5.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_26 PF13659.1 EEQ31897.1 - 1.6e-12 47.4 0.0 2.3e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ31897.1 - 0.002 17.4 1.9 0.47 9.8 0.2 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 EEQ31897.1 - 0.075 12.6 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain LSM PF01423.17 EEQ31898.1 - 9.8e-16 57.0 0.0 1.3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEQ31898.1 - 0.00014 21.6 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Gar1 PF04410.9 EEQ31898.1 - 0.061 12.7 0.1 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region API5 PF05918.6 EEQ31898.1 - 0.52 8.7 13.0 0.66 8.4 9.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2763 PF10961.3 EEQ31898.1 - 3.5 8.0 9.4 5.8 7.3 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) F-box-like PF12937.2 EEQ31899.1 - 0.00025 20.6 0.0 0.0035 17.0 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEQ31899.1 - 0.00035 20.1 0.0 0.0071 15.9 0.0 2.7 1 1 1 2 2 2 1 F-box domain DUF3568 PF12092.3 EEQ31899.1 - 0.05 13.3 0.0 0.96 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Pkinase PF00069.20 EEQ31900.1 - 1.8e-17 63.3 0.0 1.8e-12 46.9 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31900.1 - 1.4e-07 30.8 0.0 0.0015 17.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase zf-C2H2 PF00096.21 EEQ31902.1 - 3.4e-05 23.9 4.6 0.046 14.0 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ31902.1 - 4.7e-05 23.4 3.4 0.034 14.4 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ31902.1 - 0.045 14.0 0.2 0.16 12.3 0.1 2.0 1 1 0 1 1 1 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EEQ31902.1 - 0.13 12.1 1.4 11 6.0 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.1 EEQ31902.1 - 0.15 12.3 0.4 0.36 11.1 0.3 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Ank_2 PF12796.2 EEQ31904.1 - 7e-35 119.2 0.0 2.3e-11 43.8 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ31904.1 - 1.1e-28 97.5 9.9 6.2e-09 35.2 0.4 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 EEQ31904.1 - 2.5e-26 91.5 0.9 3.4e-08 33.7 0.0 6.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ31904.1 - 7.7e-25 84.4 4.6 7.2e-06 25.7 0.1 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EEQ31904.1 - 4.7e-23 80.6 0.3 0.00023 21.3 0.2 8.2 5 3 3 8 8 8 5 Ankyrin repeats (many copies) DUF3447 PF11929.3 EEQ31904.1 - 0.028 14.2 0.1 0.36 10.6 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3447) GTP_EFTU PF00009.22 EEQ31907.1 - 1.1e-09 38.0 0.0 4.8e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EEQ31907.1 - 0.0058 16.9 0.2 0.013 15.7 0.1 1.6 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EEQ31907.1 - 0.015 14.4 0.2 0.029 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEQ31907.1 - 0.036 13.5 0.1 0.091 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EEQ31907.1 - 0.16 11.4 0.1 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EEQ31907.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cullin PF00888.17 EEQ31908.1 - 7.9e-46 156.7 0.1 1.2e-45 156.1 0.1 1.2 1 0 0 1 1 1 1 Cullin family Pkr1 PF08636.5 EEQ31908.1 - 3.1e-30 104.0 4.8 9.5e-30 102.4 3.3 1.9 1 0 0 1 1 1 1 ER protein Pkr1 APC2 PF08672.6 EEQ31908.1 - 1.2e-21 76.7 0.1 2.9e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 DUF2360 PF10152.4 EEQ31908.1 - 0.31 11.3 1.9 0.55 10.5 0.1 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SNF2_N PF00176.18 EEQ31909.1 - 1.1e-30 106.4 0.0 3.9e-29 101.3 0.0 2.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 EEQ31909.1 - 8.8e-05 22.4 0.0 0.00037 20.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ31909.1 - 0.032 13.7 0.0 0.25 10.8 0.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase RasGAP_C PF03836.10 EEQ31909.1 - 0.071 12.7 0.1 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 RasGAP C-terminus Thioredoxin PF00085.15 EEQ31910.1 - 4.6e-29 100.1 0.0 5.3e-29 99.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EEQ31910.1 - 2.6e-08 34.0 0.0 3.1e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EEQ31910.1 - 1.6e-06 27.7 0.2 0.00019 20.9 0.0 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_8 PF13905.1 EEQ31910.1 - 2e-06 27.8 0.1 0.001 19.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EEQ31910.1 - 0.0001 21.9 0.3 0.0015 18.1 0.1 1.9 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EEQ31910.1 - 0.00075 19.0 0.0 0.00083 18.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EEQ31910.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like HyaE PF07449.6 EEQ31910.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 EEQ31910.1 - 0.016 15.0 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain DUF2847 PF11009.3 EEQ31910.1 - 0.054 13.0 0.0 0.08 12.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2847) Glutaredoxin PF00462.19 EEQ31910.1 - 0.06 13.3 0.1 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_4 PF13462.1 EEQ31910.1 - 0.12 12.3 0.3 0.25 11.3 0.0 1.6 1 1 1 2 2 2 0 Thioredoxin APH PF01636.18 EEQ31911.1 - 0.0021 17.8 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.2 EEQ31912.1 - 4.2e-10 39.1 1.4 1e-09 37.9 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ31912.1 - 7.1e-06 25.5 0.6 1.9e-05 24.1 0.4 1.7 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.12 EEQ31912.1 - 0.0049 16.6 0.2 0.77 9.8 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ31912.1 - 0.01 15.4 0.5 0.14 11.8 0.3 2.4 1 1 1 2 2 2 0 TPR repeat TPR_1 PF00515.23 EEQ31912.1 - 0.047 13.3 0.1 0.53 9.9 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EEQ31912.1 - 0.082 13.0 0.3 0.4 10.8 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Mito_carr PF00153.22 EEQ31913.1 - 1.8e-62 207.0 2.0 6.8e-22 76.9 0.2 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein KAR9 PF08580.5 EEQ31915.1 - 3.8e-121 405.5 0.3 3.8e-121 405.5 0.2 2.3 2 1 0 2 2 2 1 Yeast cortical protein KAR9 Tim17 PF02466.14 EEQ31915.1 - 0.041 13.9 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Alb1 PF09135.6 EEQ31916.1 - 0.0054 17.3 4.1 0.011 16.2 2.9 1.5 1 0 0 1 1 1 1 Alb1 Med25_SD1 PF11235.3 EEQ31916.1 - 0.31 11.3 5.1 0.14 12.4 1.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 DivIVA PF05103.8 EEQ31916.1 - 1.1 9.3 12.1 1.9 8.5 8.4 1.4 1 0 0 1 1 1 0 DivIVA protein polyprenyl_synt PF00348.12 EEQ31917.1 - 8.5e-51 172.2 0.0 1e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CRAL_TRIO PF00650.15 EEQ31919.1 - 7.6e-36 123.0 0.0 1.3e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EEQ31919.1 - 0.0027 17.6 0.0 0.02 14.7 0.0 2.0 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Bowman-Birk_leg PF00228.15 EEQ31920.1 - 0.098 12.4 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Bowman-Birk serine protease inhibitor family Ank_2 PF12796.2 EEQ31921.1 - 2.7e-59 197.4 1.4 9.7e-11 41.8 0.0 7.5 4 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ31921.1 - 7.1e-50 164.4 17.1 8.6e-09 34.7 0.0 13.8 14 1 0 14 14 14 10 Ankyrin repeat Ank_4 PF13637.1 EEQ31921.1 - 7.3e-46 153.7 5.7 1.2e-08 35.2 0.0 9.0 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ31921.1 - 1.3e-44 149.1 12.6 5.8e-11 42.2 0.0 9.4 7 2 3 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ31921.1 - 3e-41 135.2 10.4 3.7e-07 29.7 0.0 12.7 13 0 0 13 13 13 8 Ankyrin repeat Clathrin-link PF09268.5 EEQ31921.1 - 0.00088 18.2 0.1 0.0015 17.4 0.1 1.4 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Arg_repressor PF01316.16 EEQ31921.1 - 0.12 11.9 0.3 1.3 8.6 0.0 2.9 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain RVP PF00077.15 EEQ31921.1 - 0.27 11.1 1.0 28 4.6 0.0 3.4 3 1 0 3 3 3 0 Retroviral aspartyl protease Glyco_hydro_18 PF00704.23 EEQ31922.1 - 3.7e-59 200.9 1.8 6.2e-59 200.1 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EEQ31922.1 - 2.6e-09 36.9 30.5 1.3e-08 34.6 4.8 4.5 5 0 0 5 5 5 2 Chitin recognition protein Glyco_hydro_85 PF03644.8 EEQ31922.1 - 6.2e-05 22.2 0.1 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 LysM PF01476.15 EEQ31923.1 - 9.6e-15 54.2 0.0 8.6e-06 25.5 0.0 3.3 3 0 0 3 3 3 2 LysM domain LysM PF01476.15 EEQ31924.1 - 2.8e-15 55.9 0.0 0.0014 18.4 0.0 4.3 4 0 0 4 4 4 4 LysM domain CarbpepA_inh PF02977.10 EEQ31924.1 - 0.082 12.5 3.9 9.3 5.9 0.0 4.2 4 0 0 4 4 4 0 Carboxypeptidase A inhibitor Como_LCP PF02247.11 EEQ31924.1 - 0.11 10.8 5.4 9 4.5 0.1 3.7 4 0 0 4 4 4 0 Large coat protein UPF0203 PF05254.7 EEQ31924.1 - 0.17 11.7 8.8 7.5 6.4 0.5 3.9 3 2 0 3 3 3 0 Uncharacterised protein family (UPF0203) Acylphosphatase PF00708.13 EEQ31925.1 - 9.1e-17 60.9 0.0 1e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.12 EEQ31926.1 - 2.9e-92 307.7 0.0 3.5e-92 307.4 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase adh_short_C2 PF13561.1 EEQ31927.1 - 5.4e-25 88.5 0.0 6.8e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ31927.1 - 2.7e-24 85.9 0.0 3.5e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ31927.1 - 1.8e-06 27.7 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEQ31927.1 - 0.075 12.8 0.0 0.26 11.1 0.0 2.0 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EEQ31927.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MBOAT PF03062.14 EEQ31928.1 - 1.5e-46 158.9 12.1 2.8e-46 158.1 8.4 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family FA_desaturase PF00487.19 EEQ31929.1 - 1.1e-32 113.4 22.2 2e-32 112.6 15.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EEQ31929.1 - 1.7e-10 40.5 0.0 3.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain APH PF01636.18 EEQ31930.1 - 1.7e-05 24.6 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family STAT2_C PF12188.3 EEQ31930.1 - 0.1 12.4 0.1 2.2 8.1 0.0 2.8 3 0 0 3 3 3 0 Signal transducer and activator of transcription 2 C terminal Choline_kinase PF01633.15 EEQ31930.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA PF00004.24 EEQ31931.1 - 5e-15 55.8 0.0 8.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EEQ31931.1 - 1.8e-06 27.7 0.5 2.8e-06 27.0 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA_17 PF13207.1 EEQ31931.1 - 0.00021 22.0 0.0 0.00049 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ31931.1 - 0.00026 20.1 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEQ31931.1 - 0.0019 17.9 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EEQ31931.1 - 0.0078 15.9 0.0 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EEQ31931.1 - 0.0082 16.4 0.0 0.031 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ31931.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EEQ31931.1 - 0.027 13.8 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1841 PF08897.6 EEQ31931.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) AphA_like PF14557.1 EEQ31931.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator TIP49 PF06068.8 EEQ31931.1 - 0.11 11.1 0.1 0.28 9.8 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus AAA_11 PF13086.1 EEQ31931.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Engrail_1_C_sig PF10525.4 EEQ31933.1 - 8.9 5.5 6.9 1.1e+02 2.0 0.1 4.0 4 0 0 4 4 4 0 Engrailed homeobox C-terminal signature domain zf-HIT PF04438.11 EEQ31936.1 - 2.2e-10 39.9 7.1 3.3e-10 39.4 4.9 1.3 1 0 0 1 1 1 1 HIT zinc finger Dopey_N PF04118.9 EEQ31937.1 - 2.4e-121 404.2 0.0 7.3e-121 402.6 0.0 1.9 1 0 0 1 1 1 1 Dopey, N-terminal Mon1 PF03164.9 EEQ31938.1 - 7.7e-118 393.6 0.0 9.1e-118 393.4 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DEAD PF00270.24 EEQ31939.1 - 6.9e-23 80.9 0.1 1.6e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ31939.1 - 7.6e-21 73.7 0.2 1.4e-17 63.3 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 EEQ31939.1 - 2.4e-14 52.9 0.0 5.4e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EEQ31939.1 - 8.4e-08 31.8 0.0 2.4e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 HRDC domain FlgN PF05130.7 EEQ31939.1 - 0.031 14.5 1.1 0.082 13.1 0.8 1.7 1 0 0 1 1 1 0 FlgN protein DUF4110 PF13422.1 EEQ31940.1 - 2.2e-29 101.1 0.1 2.2e-29 101.1 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 EEQ31940.1 - 1.8e-23 81.9 13.2 2.3e-09 36.8 0.0 7.0 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EEQ31940.1 - 3.7e-22 77.8 12.1 2e-09 37.3 0.0 7.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EEQ31940.1 - 1e-16 60.2 3.2 0.0016 18.5 0.1 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 EEQ31940.1 - 1.7e-12 47.0 5.9 0.0016 18.3 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EEQ31940.1 - 1.6e-10 40.3 3.9 0.35 10.7 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EEQ31940.1 - 2.2e-09 36.7 0.9 0.014 14.9 0.0 4.8 4 0 0 4 4 4 2 Kelch motif CENP-B_dimeris PF09026.5 EEQ31940.1 - 3 8.1 21.3 0.26 11.5 9.1 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Pyridoxal_deC PF00282.14 EEQ31941.1 - 7.8e-31 106.8 0.0 1.1e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EEQ31941.1 - 0.0087 15.2 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EEQ31941.1 - 0.025 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_hydro_61 PF03443.9 EEQ31942.1 - 0.021 14.6 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 61 Chitin_bind_3 PF03067.10 EEQ31942.1 - 0.07 13.3 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 Chitin binding domain MIF4G PF02854.14 EEQ31944.1 - 1.2e-52 178.4 0.0 1.8e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EEQ31944.1 - 4.4e-23 80.9 2.0 1.3e-22 79.4 1.4 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 TB2_DP1_HVA22 PF03134.14 EEQ31945.1 - 5.8e-22 77.2 7.0 1.9e-21 75.6 4.8 1.8 1 1 0 1 1 1 1 TB2/DP1, HVA22 family F-box-like PF12937.2 EEQ31946.1 - 3e-05 23.6 0.3 8.2e-05 22.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EEQ31946.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 PRANC domain F-box PF00646.28 EEQ31946.1 - 0.0048 16.5 0.4 0.014 15.0 0.3 1.8 1 0 0 1 1 1 1 F-box domain APH PF01636.18 EEQ31948.1 - 0.0099 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 EEQ31949.1 - 4.3e-14 51.9 51.9 9.1e-09 34.4 12.3 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ31949.1 - 8.3e-05 21.3 12.3 8.3e-05 21.3 8.5 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4407 PF14362.1 EEQ31949.1 - 6.8 5.5 6.4 16 4.3 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NRDE PF05742.7 EEQ31950.1 - 2e-35 122.4 0.0 3.3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 NRDE protein BPL_N PF09825.4 EEQ31951.1 - 6.8e-126 419.9 0.1 1.4e-125 418.9 0.0 1.5 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EEQ31951.1 - 2.7e-20 72.6 0.0 4.8e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EEQ31951.1 - 6.1e-05 22.6 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Mgm101p PF06420.7 EEQ31953.1 - 4.4e-78 260.4 0.9 9.5e-77 256.1 0.6 2.1 1 1 0 1 1 1 1 Mitochondrial genome maintenance MGM101 eIF-1a PF01176.14 EEQ31953.1 - 0.15 11.4 0.2 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 MAP65_ASE1 PF03999.7 EEQ31953.1 - 6.3 5.2 6.0 8.1 4.9 4.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) zf-RING_2 PF13639.1 EEQ31954.1 - 5.7e-13 48.4 3.2 9.6e-13 47.7 2.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ31954.1 - 5.2e-07 29.5 1.8 8.4e-07 28.9 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ31954.1 - 6.9e-07 28.8 0.5 1.1e-06 28.1 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ31954.1 - 1.1e-05 25.4 0.2 2.1e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEQ31954.1 - 0.00015 21.4 0.6 0.00026 20.6 0.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ31954.1 - 0.00039 20.0 0.7 0.00062 19.3 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ31954.1 - 0.028 14.2 1.0 0.057 13.2 0.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EEQ31954.1 - 0.12 12.4 0.4 0.32 10.9 0.3 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain Phage_lysozyme PF00959.14 EEQ31956.1 - 8.2e-14 51.8 0.0 1.1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme Stanniocalcin PF03298.8 EEQ31957.1 - 0.00037 19.5 0.1 0.00048 19.2 0.1 1.1 1 0 0 1 1 1 1 Stanniocalcin family MS_channel PF00924.13 EEQ31958.1 - 3.5e-18 65.6 0.6 3.5e-18 65.6 0.4 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EEQ31958.1 - 0.041 13.2 0.3 0.11 11.8 0.2 1.8 1 0 0 1 1 1 0 EF hand FA_desaturase PF00487.19 EEQ31958.1 - 0.67 9.3 7.8 4.2 6.7 2.3 2.4 2 0 0 2 2 2 0 Fatty acid desaturase Aminotran_1_2 PF00155.16 EEQ31960.1 - 1.5e-79 267.5 0.0 1.8e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cut8_N PF14482.1 EEQ31961.1 - 0.74 9.8 6.6 1.6 8.7 4.6 1.8 1 1 0 1 1 1 0 Cut8 proteasome-binding domain DUF3464 PF11947.3 EEQ31961.1 - 2.6 7.4 6.2 1.1 8.7 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3464) Syntaxin-18_N PF10496.4 EEQ31962.1 - 1.5e-13 50.3 0.0 3.9e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus TPR_1 PF00515.23 EEQ31963.1 - 1.9e-14 52.5 4.0 6.1e-07 28.7 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ31963.1 - 1.2e-13 49.8 3.7 7.4e-05 22.3 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ31963.1 - 1.2e-12 47.2 4.2 1.1e-09 37.7 0.1 3.4 3 0 0 3 3 3 2 TPR repeat PB1 PF00564.19 EEQ31963.1 - 8.5e-09 34.9 0.1 1.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.1 EEQ31963.1 - 1.4e-07 31.3 0.3 0.00026 20.8 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ31963.1 - 3.6e-07 29.5 0.7 0.028 14.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ31963.1 - 2.1e-06 27.0 0.5 0.00014 21.4 0.1 3.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ31963.1 - 2.1e-05 24.3 0.9 0.0025 17.8 0.1 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ31963.1 - 4.7e-05 23.5 0.1 11 6.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ31963.1 - 0.00021 21.8 1.1 0.045 14.4 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ31963.1 - 0.0023 17.7 0.1 1.2 9.0 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ31963.1 - 0.0043 17.5 2.2 0.32 11.7 0.0 3.6 2 1 2 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ31963.1 - 0.21 11.7 2.4 0.82 9.8 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sod_Cu PF00080.15 EEQ31964.1 - 5.8e-14 52.4 0.0 8.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EEQ31964.1 - 3.2e-11 43.1 0.0 6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Chordopox_RPO7 PF05864.7 EEQ31964.1 - 0.054 13.5 0.1 6 7.0 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Pkinase PF00069.20 EEQ31965.1 - 2.5e-62 210.3 0.0 3.8e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31965.1 - 1.2e-26 93.3 0.0 2e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ31965.1 - 0.00039 19.4 0.0 0.0024 16.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EEQ31965.1 - 0.0093 15.3 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DMAP1 PF05499.7 EEQ31965.1 - 0.075 12.5 6.0 9 5.8 4.9 2.2 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) APH PF01636.18 EEQ31965.1 - 0.14 11.8 2.9 0.35 10.5 2.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Imm5 PF14423.1 EEQ31967.1 - 0.058 13.0 0.4 0.091 12.3 0.3 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 AMP-binding PF00501.23 EEQ31968.1 - 1.6e-239 794.3 0.0 8e-81 271.5 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EEQ31968.1 - 5.9e-133 442.3 0.1 5.2e-44 150.3 0.0 4.4 4 0 0 4 4 4 4 Condensation domain NAD_binding_4 PF07993.7 EEQ31968.1 - 2.2e-38 131.5 0.0 4.3e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EEQ31968.1 - 3.4e-36 123.3 1.9 4.2e-11 42.9 0.0 4.1 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ31968.1 - 1.6e-18 67.3 0.3 1.9e-05 25.5 0.0 4.4 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EEQ31968.1 - 4.1e-11 42.7 0.0 7.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ31968.1 - 0.00056 18.6 0.0 0.001 17.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2844 PF11005.3 EEQ31968.1 - 0.023 14.5 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) AATase PF07247.7 EEQ31968.1 - 0.03 12.8 0.0 7 5.0 0.0 4.0 3 2 0 3 3 3 0 Alcohol acetyltransferase Transferase PF02458.10 EEQ31968.1 - 0.15 10.5 0.0 0.46 8.8 0.0 1.7 2 0 0 2 2 2 0 Transferase family Usp PF00582.21 EEQ31969.1 - 1.6e-20 73.7 1.6 3.2e-20 72.7 0.0 2.2 2 0 0 2 2 2 1 Universal stress protein family MAD PF05557.8 EEQ31970.1 - 0.0058 14.7 0.5 0.0072 14.4 0.4 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Transposase_mut PF00872.13 EEQ31970.1 - 0.11 11.0 0.1 0.18 10.2 0.0 1.3 1 1 0 1 1 1 0 Transposase, Mutator family DUF3357 PF11837.3 EEQ31971.1 - 0.0094 15.7 3.7 0.01 15.6 1.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3357) SpoIIIAH PF12685.2 EEQ31971.1 - 0.06 12.8 1.3 0.096 12.1 0.9 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF3827 PF12877.2 EEQ31971.1 - 4.9 5.1 5.7 6.7 4.6 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SNF2_N PF00176.18 EEQ31972.1 - 1.2e-70 237.6 0.0 2.2e-70 236.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ31972.1 - 6e-14 51.6 0.0 1.7e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 EEQ31973.1 - 1.2e-26 93.4 3.6 9.5e-25 87.2 0.6 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ31973.1 - 1.8e-13 50.1 1.0 1.8e-13 50.1 0.7 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ31973.1 - 0.0049 15.7 0.1 0.0094 14.7 0.0 1.4 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EEQ31973.1 - 0.019 14.3 0.2 0.069 12.4 0.1 1.8 1 1 0 1 1 1 0 RIO1 family APH PF01636.18 EEQ31973.1 - 0.034 13.8 0.1 0.034 13.8 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Foie-gras_1 PF11817.3 EEQ31973.1 - 0.11 11.9 2.0 0.22 10.9 1.4 1.5 1 0 0 1 1 1 0 Foie gras liver health family 1 DUF4430 PF14478.1 EEQ31973.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) eIF-3c_N PF05470.7 EEQ31974.1 - 1.3e-147 492.5 46.6 1.1e-66 225.2 0.2 4.2 1 1 2 4 4 4 3 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EEQ31974.1 - 8.9e-12 45.2 0.1 8.9e-12 45.2 0.1 3.6 3 2 2 5 5 5 1 PCI domain Daxx PF03344.10 EEQ31974.1 - 7.1 4.9 24.6 12 4.2 17.1 1.2 1 0 0 1 1 1 0 Daxx Family EAP30 PF04157.11 EEQ31975.1 - 2.3e-57 193.6 0.0 2.8e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_L30_N PF08079.7 EEQ31976.1 - 7.1e-25 86.8 15.3 1.2e-24 86.0 10.6 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EEQ31976.1 - 2e-18 65.7 3.1 2.8e-18 65.2 1.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_B PF00136.16 EEQ31977.1 - 3.4e-114 382.2 2.9 3.4e-114 382.2 2.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EEQ31977.1 - 2.4e-66 222.7 1.7 3.4e-66 222.2 0.3 2.0 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EEQ31977.1 - 8.6e-43 146.4 0.0 2e-42 145.2 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EEQ31977.1 - 2.3e-25 88.2 11.0 2.3e-25 88.2 7.6 3.2 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal PPR_2 PF13041.1 EEQ31979.1 - 2.1e-16 59.5 0.0 3.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.15 EEQ31979.1 - 2.9e-06 26.8 0.3 9.4e-05 22.1 0.2 2.5 2 0 0 2 2 2 1 PPR repeat PPR_1 PF12854.2 EEQ31979.1 - 7.7e-06 25.2 0.0 0.091 12.2 0.0 2.3 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.1 EEQ31979.1 - 8e-06 25.7 0.0 0.00011 22.1 0.0 2.7 2 0 0 2 2 2 1 Pentatricopeptide repeat domain Terminase_6 PF03237.10 EEQ31979.1 - 0.078 11.7 1.7 0.065 11.9 0.2 1.5 1 1 1 2 2 2 0 Terminase-like family Ring_hydroxyl_B PF00866.13 EEQ31979.1 - 0.094 12.4 6.7 0.99 9.0 0.1 3.0 3 0 0 3 3 3 0 Ring hydroxylating beta subunit DEAD PF00270.24 EEQ31981.1 - 4e-46 156.5 0.0 7.4e-44 149.2 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ31981.1 - 6.4e-27 93.2 0.0 1.6e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ31981.1 - 0.00011 22.1 0.0 0.00036 20.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EEQ31981.1 - 0.00081 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2443 PF10398.4 EEQ31981.1 - 0.033 13.9 0.4 0.071 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA_19 PF13245.1 EEQ31981.1 - 0.045 13.5 1.0 2.1 8.1 0.2 3.0 3 1 0 3 3 3 0 Part of AAA domain CMS1 PF14617.1 EEQ31981.1 - 0.061 12.3 0.9 0.99 8.4 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EEQ31981.1 - 0.062 11.6 0.0 1.8 6.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EEQ31981.1 - 0.33 11.1 1.3 6.4 6.9 0.2 3.0 1 1 0 2 2 2 0 AAA domain Phos_pyr_kin PF08543.7 EEQ31982.1 - 5e-71 238.7 0.6 7.9e-71 238.1 0.4 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EEQ31982.1 - 1.1e-42 146.1 1.6 3.4e-29 102.1 0.0 2.3 1 1 1 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.19 EEQ31982.1 - 1.4e-08 34.2 0.1 2.4e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EEQ31982.1 - 0.006 15.7 1.1 0.028 13.5 0.1 2.1 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TroA PF01297.12 EEQ31982.1 - 0.024 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Periplasmic solute binding protein family APH PF01636.18 EEQ31987.1 - 1e-12 48.3 0.1 9.3e-12 45.1 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ31987.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ31987.1 - 0.0036 16.0 0.0 1.6 7.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.20 EEQ31987.1 - 0.013 14.6 0.0 0.66 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.9 EEQ31987.1 - 0.046 12.7 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EEQ31987.1 - 0.066 12.2 0.1 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Sds3 PF08598.6 EEQ31988.1 - 1.1e-46 159.0 11.6 6.1e-46 156.5 8.1 1.9 1 1 0 1 1 1 1 Sds3-like CFEM PF05730.6 EEQ31991.1 - 0.00017 21.3 4.6 0.00017 21.3 3.2 2.2 2 0 0 2 2 2 1 CFEM domain APH PF01636.18 EEQ31992.1 - 3.9e-10 39.8 0.1 5.8e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ31992.1 - 0.00027 20.5 0.0 0.00047 19.7 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1590 PF07629.6 EEQ31992.1 - 0.00087 18.8 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1590) Pkinase PF00069.20 EEQ31992.1 - 0.12 11.4 0.0 10 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Nucleoplasmin PF03066.10 EEQ31993.1 - 0.023 14.2 0.7 0.023 14.2 0.5 4.4 5 1 0 5 5 5 0 Nucleoplasmin eIF-3c_N PF05470.7 EEQ31993.1 - 0.51 8.3 5.1 0.87 7.5 3.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PilO PF04350.8 EEQ31994.1 - 0.0047 16.8 0.4 0.0047 16.8 0.3 2.2 1 1 1 2 2 2 1 Pilus assembly protein, PilO Baculo_PEP_C PF04513.7 EEQ31994.1 - 0.0061 16.3 1.9 0.011 15.5 0.5 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2752 PF10825.3 EEQ31994.1 - 0.072 13.1 1.6 0.12 12.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Dfp1_Him1_M PF08630.5 EEQ31994.1 - 0.33 10.7 6.4 3.1 7.6 0.3 2.8 1 1 2 3 3 3 0 Dfp1/Him1, central region DUF4109 PF13397.1 EEQ31994.1 - 1 9.7 9.6 0.8 10.1 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4109) Sterol_MT_C PF08498.5 EEQ31996.1 - 1.1e-22 79.7 0.3 1.8e-22 79.0 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EEQ31996.1 - 4.1e-19 68.8 0.0 7.4e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ31996.1 - 5.8e-17 61.6 0.0 8e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ31996.1 - 2.6e-13 50.5 0.0 5.6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ31996.1 - 1.2e-12 47.8 0.0 1.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEQ31996.1 - 1.3e-12 47.3 0.0 1.7e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EEQ31996.1 - 9.1e-12 45.3 0.0 1.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ31996.1 - 4e-11 42.4 0.0 8.1e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EEQ31996.1 - 1.9e-10 41.0 0.0 3.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ31996.1 - 8.3e-07 29.0 0.0 2.3e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ31996.1 - 0.00028 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EEQ31996.1 - 0.00036 19.9 0.0 0.00075 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EEQ31996.1 - 0.0055 16.2 0.1 0.0078 15.7 0.1 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EEQ31996.1 - 0.0089 15.1 0.0 0.018 14.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.1 EEQ31996.1 - 0.12 13.2 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EEQ31996.1 - 0.18 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase BTB PF00651.26 EEQ31997.1 - 2.1e-06 27.7 0.0 8e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Peptidase_S24 PF00717.18 EEQ31998.1 - 3.6e-08 32.9 0.0 6.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.21 EEQ32001.1 - 4.6e-42 142.7 0.0 5.1e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ32001.1 - 6.1e-08 32.4 0.0 7.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EEQ32001.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EEQ32001.1 - 0.025 14.4 0.2 0.029 14.2 0.1 1.6 1 1 0 1 1 1 0 RWD domain Acyl_transf_3 PF01757.17 EEQ32002.1 - 4.2e-14 52.1 27.9 1.1e-13 50.7 19.2 1.9 1 1 0 1 1 1 1 Acyltransferase family Trp_leader2 PF08056.6 EEQ32003.1 - 0.63 10.0 4.0 0.6 10.1 1.5 1.9 2 0 0 2 2 2 0 Tryptophan operon leader peptide RabGAP-TBC PF00566.13 EEQ32004.1 - 2e-36 125.4 0.1 9.4e-36 123.2 0.0 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain BCS1_N PF08740.6 EEQ32006.1 - 6.8e-54 182.3 0.2 9.2e-54 181.9 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEQ32006.1 - 7.4e-19 68.2 0.0 1.5e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEQ32006.1 - 1.9e-05 24.9 0.0 0.003 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEQ32006.1 - 5.7e-05 23.9 0.0 0.00014 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ32006.1 - 0.00025 21.0 0.1 0.0013 18.7 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EEQ32006.1 - 0.00048 19.1 0.0 0.00096 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EEQ32006.1 - 0.00084 19.2 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ32006.1 - 0.0037 17.4 0.0 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EEQ32006.1 - 0.01 15.5 0.0 0.04 13.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EEQ32006.1 - 0.011 15.1 0.1 0.046 13.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEQ32006.1 - 0.019 14.7 0.1 0.078 12.7 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 EEQ32006.1 - 0.021 14.3 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EEQ32006.1 - 0.029 14.5 0.0 0.093 12.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.22 EEQ32006.1 - 0.032 14.5 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.1 EEQ32006.1 - 0.055 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EEQ32006.1 - 0.06 12.5 0.0 0.29 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 KaiC PF06745.8 EEQ32006.1 - 0.066 12.3 0.0 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 KaiC DUF2735 PF10931.3 EEQ32006.1 - 0.096 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) Zeta_toxin PF06414.7 EEQ32006.1 - 0.11 11.6 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 EEQ32006.1 - 0.15 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Methyltransf_25 PF13649.1 EEQ32008.1 - 1.8e-14 53.9 0.0 4.7e-14 52.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ32008.1 - 6.6e-05 23.3 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ32008.1 - 0.00011 22.7 0.0 0.00037 21.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ32008.1 - 0.00019 21.2 0.0 0.0015 18.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ32008.1 - 0.00072 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ32008.1 - 0.004 16.7 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ32008.1 - 0.0081 16.6 0.0 0.022 15.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ric8 PF10165.4 EEQ32008.1 - 0.16 10.7 0.0 0.36 9.5 0.0 1.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Cpn60_TCP1 PF00118.19 EEQ32009.1 - 3.1e-163 543.8 0.5 3.5e-163 543.7 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 EEQ32010.1 - 1.4e-43 147.7 11.6 1.9e-43 147.3 8.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) eIF-3_zeta PF05091.7 EEQ32010.1 - 0.04 12.5 2.0 0.045 12.3 1.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S49_N PF08496.5 EEQ32010.1 - 0.68 9.7 3.3 0.97 9.2 2.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNA_polI_A34 PF08208.6 EEQ32010.1 - 1.3 8.6 15.0 1.8 8.2 10.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EEQ32010.1 - 2.3 7.3 6.5 2.5 7.2 4.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) NARP1 PF12569.3 EEQ32010.1 - 6.7 5.3 10.5 8.9 4.9 7.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-PARP PF00645.13 EEQ32011.1 - 1.7e-21 76.2 0.3 1.7e-21 76.2 0.2 2.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF936 PF06075.7 EEQ32011.1 - 0.17 10.7 34.2 0.21 10.4 23.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Kinesin PF00225.18 EEQ32012.1 - 5.7e-55 186.3 0.0 1.4e-54 185.0 0.0 1.7 1 1 0 1 1 1 1 Kinesin motor domain DUF4140 PF13600.1 EEQ32012.1 - 5.6 7.4 8.3 2.9 8.3 0.1 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) TPR_11 PF13414.1 EEQ32013.1 - 0.065 12.8 3.8 4.1 7.1 0.1 3.7 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.1 EEQ32013.1 - 0.49 11.1 3.6 9.5 7.1 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 EEQ32014.1 - 3e-155 516.8 0.0 4e-155 516.4 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EEQ32014.1 - 7e-05 22.3 0.2 0.023 14.3 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EEQ32014.1 - 0.00011 21.6 0.1 6.2 6.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ32014.1 - 0.00013 22.3 1.2 4.7 8.1 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ32014.1 - 0.00015 21.4 0.1 0.86 9.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ32014.1 - 0.00086 19.3 0.0 0.15 12.2 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEQ32014.1 - 0.0016 18.2 0.2 1 9.2 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ32014.1 - 0.003 17.2 0.0 2.9 7.9 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ32014.1 - 0.011 15.7 0.6 0.73 9.8 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ32014.1 - 0.024 14.4 0.9 31 4.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ32014.1 - 0.034 14.4 0.0 5.5 7.3 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat YejG PF13989.1 EEQ32014.1 - 0.14 12.2 0.2 0.65 10.0 0.0 2.1 2 0 0 2 2 2 0 YejG-like protein Exo5 PF09810.4 EEQ32016.1 - 2.3e-97 326.1 0.0 5e-97 325.0 0.0 1.5 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EEQ32016.1 - 5.3e-05 22.7 0.4 0.0059 16.0 0.0 3.3 3 1 0 3 3 3 1 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.7 EEQ32017.1 - 3.6e-16 58.5 0.3 3.6e-16 58.5 0.2 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family Histone PF00125.19 EEQ32018.1 - 3.3e-30 103.9 0.5 5.4e-30 103.3 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEQ32018.1 - 2.7e-06 27.4 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EEQ32018.1 - 0.0059 16.3 0.1 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 EEQ32018.1 - 0.0081 16.2 0.2 0.026 14.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ32019.1 - 2e-15 56.6 0.2 2.4e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEQ32019.1 - 6.4e-05 23.0 0.1 9.1e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EEQ32019.1 - 9e-05 22.3 0.1 0.00013 21.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EEQ32019.1 - 0.00016 21.6 0.1 0.00034 20.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEQ32019.1 - 0.007 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EEQ32019.1 - 0.035 13.3 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 EEQ32019.1 - 0.043 14.0 0.1 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 EEQ32019.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TGT PF01702.13 EEQ32020.1 - 0.26 10.5 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase zf-C2H2 PF00096.21 EEQ32022.1 - 4.7e-07 29.7 24.3 0.00038 20.6 0.9 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ32022.1 - 0.00037 20.6 26.8 0.003 17.7 0.9 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger Macoilin PF09726.4 EEQ32022.1 - 7.5 4.7 8.5 19 3.3 5.9 1.6 1 0 0 1 1 1 0 Transmembrane protein Glyco_transf_22 PF03901.12 EEQ32023.1 - 5.5e-88 295.7 19.9 6.3e-88 295.5 13.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HET PF06985.6 EEQ32024.1 - 2.8e-24 85.8 0.0 5.8e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gar1 PF04410.9 EEQ32025.1 - 4e-39 133.5 0.1 4e-39 133.5 0.1 2.6 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region EPSP_synthase PF00275.15 EEQ32026.1 - 1.1e-130 435.8 0.0 1.7e-130 435.2 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EEQ32026.1 - 7.6e-98 326.5 0.0 1.7e-97 325.4 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EEQ32026.1 - 1.9e-63 214.1 0.0 3.5e-63 213.2 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EEQ32026.1 - 8e-38 129.7 0.2 1.8e-37 128.6 0.0 1.8 2 0 0 2 2 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 EEQ32026.1 - 6e-24 83.9 0.0 1.7e-23 82.4 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EEQ32026.1 - 7.2e-13 48.8 0.0 2e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EEQ32026.1 - 7.3e-09 35.2 0.0 3.9e-08 32.9 0.0 2.2 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EEQ32026.1 - 1.8e-06 26.8 0.7 5.2e-06 25.3 0.5 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EEQ32026.1 - 2.7e-05 24.9 0.1 0.00018 22.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain NurA PF09376.5 EEQ32026.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 NurA domain TPR_1 PF00515.23 EEQ32026.1 - 0.17 11.5 0.4 24 4.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat XRN_N PF03159.13 EEQ32027.1 - 1e-99 332.7 0.0 1e-99 332.7 0.0 2.3 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Uso1_p115_head PF04869.9 EEQ32028.1 - 5.3e-110 367.0 0.0 2.4e-109 364.8 0.0 2.2 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EEQ32028.1 - 8.2e-07 29.0 28.8 8.2e-07 29.0 19.9 3.5 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region IncA PF04156.9 EEQ32028.1 - 0.17 11.4 58.8 0.089 12.3 16.1 3.4 1 1 1 2 2 2 0 IncA protein DUF3584 PF12128.3 EEQ32028.1 - 0.42 7.8 49.0 0.66 7.2 34.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 EEQ32028.1 - 0.51 9.7 49.6 0.56 9.6 32.1 2.4 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.6 EEQ32028.1 - 0.51 8.9 43.6 0.053 12.1 4.7 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.1 EEQ32028.1 - 1.2 8.2 41.9 0.037 13.2 18.5 2.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2570 PF10828.3 EEQ32028.1 - 8.7 5.9 33.3 0.074 12.6 6.9 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF2570) tRNA-synt_1 PF00133.17 EEQ32029.1 - 5.4e-207 688.5 0.0 2.5e-113 379.1 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEQ32029.1 - 1.7e-24 86.3 0.0 4.7e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEQ32029.1 - 1.3e-17 63.5 0.1 1.2e-07 30.7 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EEQ32029.1 - 0.11 11.5 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain NDUF_B7 PF05676.8 EEQ32030.1 - 0.0077 15.6 0.8 2 7.9 0.0 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 EEQ32030.1 - 0.029 14.2 2.4 0.35 10.8 1.5 2.0 1 1 1 2 2 2 0 CHCH domain Cmc1 PF08583.5 EEQ32030.1 - 0.07 12.9 3.3 0.13 12.0 2.3 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 EEQ32030.1 - 0.18 11.6 1.4 3.1 7.7 0.9 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) p450 PF00067.17 EEQ32031.1 - 2.3e-74 250.5 0.0 3.6e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EEQ32031.1 - 4.2e-34 117.8 0.0 7.8e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EEQ32031.1 - 5.3e-20 71.8 0.0 1.1e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EEQ32031.1 - 1.3e-14 54.6 0.0 2.9e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EEQ32031.1 - 0.00042 20.3 0.0 0.00096 19.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 EEQ32031.1 - 0.17 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 NrdI Flavodoxin like Sfi1 PF08457.5 EEQ32032.1 - 3.5e-140 468.1 82.4 2.8e-139 465.1 51.4 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein DUF454 PF04304.8 EEQ32032.1 - 0.068 13.1 0.2 17 5.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Elongin_A PF06881.6 EEQ32033.1 - 2.7e-23 82.4 1.5 4.7e-23 81.6 1.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A FAM220 PF15487.1 EEQ32033.1 - 1 8.6 5.0 1.7 7.9 3.5 1.4 1 0 0 1 1 1 0 FAM220 family F-box-like PF12937.2 EEQ32034.1 - 0.013 15.2 0.3 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EEQ32034.1 - 0.043 13.4 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 F-box domain DUF1183 PF06682.7 EEQ32035.1 - 2 7.9 7.5 1.7 8.1 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Sugar_tr PF00083.19 EEQ32036.1 - 3e-71 240.3 20.3 5.3e-70 236.2 14.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ32036.1 - 3.2e-10 39.2 30.2 8.4e-05 21.4 10.3 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily EBP PF05241.7 EEQ32036.1 - 0.076 12.0 8.9 0.012 14.5 2.0 2.2 2 0 0 2 2 2 0 Emopamil binding protein Band_7 PF01145.20 EEQ32037.1 - 2e-15 57.1 0.1 2e-15 57.1 0.1 2.1 2 1 0 2 2 2 1 SPFH domain / Band 7 family APC_CDC26 PF10471.4 EEQ32038.1 - 1.9 9.3 13.5 7.2 7.4 0.5 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 TBCA PF02970.11 EEQ32039.1 - 7.8e-24 83.5 9.9 9.3e-24 83.3 6.9 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF2972 PF11186.3 EEQ32039.1 - 0.016 15.0 1.1 0.019 14.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) D123 PF07065.9 EEQ32039.1 - 0.041 12.9 1.2 0.043 12.8 0.8 1.0 1 0 0 1 1 1 0 D123 IncA PF04156.9 EEQ32039.1 - 0.11 12.0 8.9 0.13 11.8 6.1 1.1 1 0 0 1 1 1 0 IncA protein DUF2570 PF10828.3 EEQ32039.1 - 0.18 11.3 5.6 0.23 11.0 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Fib_alpha PF08702.5 EEQ32039.1 - 0.21 11.6 2.8 0.24 11.4 1.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HSP70 PF00012.15 EEQ32039.1 - 0.25 9.2 7.7 0.28 9.0 5.3 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF342 PF03961.8 EEQ32039.1 - 0.45 8.8 6.0 0.5 8.7 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_23 PF13476.1 EEQ32039.1 - 0.57 10.4 8.6 0.74 10.1 6.0 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EEQ32039.1 - 0.91 7.3 4.3 0.98 7.1 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EEQ32039.1 - 1 9.0 12.8 1.9 8.1 8.8 1.6 1 1 0 1 1 1 0 Mnd1 family TMF_DNA_bd PF12329.3 EEQ32039.1 - 1.1 9.1 15.4 1.7 8.5 2.4 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.11 EEQ32039.1 - 1.2 9.3 6.1 1.9 8.7 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Atg14 PF10186.4 EEQ32039.1 - 1.7 7.5 6.3 1.9 7.3 4.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 THOC7 PF05615.8 EEQ32040.1 - 2.2e-39 134.8 11.9 2.2e-39 134.8 8.3 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 CCDC92 PF14916.1 EEQ32040.1 - 0.02 14.4 2.1 0.021 14.4 0.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function CDC37_N PF03234.9 EEQ32040.1 - 0.082 13.2 8.2 0.18 12.0 5.7 1.6 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1843 PF08898.5 EEQ32040.1 - 0.089 12.8 0.5 0.089 12.8 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) FUSC PF04632.7 EEQ32040.1 - 0.1 10.9 5.0 0.15 10.4 3.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family SSFA2_C PF14723.1 EEQ32040.1 - 0.17 11.6 2.9 0.32 10.7 2.0 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus zf-C4H2 PF10146.4 EEQ32040.1 - 0.8 9.6 15.1 0.076 13.0 4.7 2.5 1 1 2 3 3 3 0 Zinc finger-containing protein SseC PF04888.7 EEQ32040.1 - 1 8.5 6.1 5.1 6.3 1.6 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family PTR2 PF00854.16 EEQ32041.1 - 2.7e-55 187.6 14.1 9e-55 185.9 9.8 1.8 1 1 0 1 1 1 1 POT family Malic_M PF03949.10 EEQ32042.1 - 4e-87 292.0 0.0 5.2e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EEQ32042.1 - 3.1e-62 209.4 0.0 5.3e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Kinesin PF00225.18 EEQ32044.1 - 3.9e-48 163.8 0.0 2.1e-33 115.4 0.1 2.2 2 0 0 2 2 2 2 Kinesin motor domain DUF4449 PF14613.1 EEQ32045.1 - 0.00031 20.7 1.2 0.00088 19.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) NAAA-beta PF15508.1 EEQ32045.1 - 0.022 15.1 1.0 3.1 8.2 0.0 4.0 4 0 0 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1338 PF07063.8 EEQ32045.1 - 0.045 12.8 0.6 0.098 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) DUF1367 PF07105.6 EEQ32045.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) DUF4208 PF13907.1 EEQ32045.1 - 0.071 13.3 0.2 0.53 10.5 0.0 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) DnaJ PF00226.26 EEQ32046.1 - 1.7e-23 82.1 2.2 2.6e-23 81.5 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEQ32046.1 - 1.1e-14 54.2 16.7 1.8e-14 53.5 11.6 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EEQ32046.1 - 8.7e-10 38.3 0.0 3.6e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EEQ32046.1 - 0.13 12.0 6.9 1.1 8.9 0.4 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EEQ32046.1 - 5.6 6.8 12.8 16 5.4 1.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon SKG6 PF08693.5 EEQ32048.1 - 0.0097 15.2 0.5 0.019 14.2 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DIPSY PF11763.3 EEQ32049.1 - 0.095 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal ADH_N PF08240.7 EEQ32050.1 - 0.00024 20.8 0.2 0.00049 19.8 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain S4 PF01479.20 EEQ32051.1 - 7.3e-10 38.1 0.0 1.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EEQ32051.1 - 8e-05 22.9 2.5 0.00012 22.4 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain PilP PF04351.8 EEQ32051.1 - 0.014 15.3 0.1 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilP YopR_core PF09025.5 EEQ32051.1 - 0.063 13.2 0.1 0.17 11.8 0.1 1.9 1 1 0 1 1 1 0 YopR Core MFS_1 PF07690.11 EEQ32054.1 - 7.2e-28 97.2 28.8 7.2e-28 97.2 20.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.16 EEQ32055.1 - 2e-41 141.3 0.7 3.3e-41 140.6 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.1 EEQ32055.1 - 0.00066 19.9 1.1 0.00066 19.9 0.8 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily tRNA-synt_1b PF00579.20 EEQ32058.1 - 4e-64 216.5 0.0 4.9e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) LRR_4 PF12799.2 EEQ32059.1 - 7.8e-56 184.9 63.1 5e-09 35.5 1.4 12.8 8 3 5 13 13 13 11 Leucine Rich repeats (2 copies) PP2C PF00481.16 EEQ32059.1 - 2.2e-53 181.2 0.0 3.3e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 EEQ32059.1 - 2.9e-43 145.4 65.8 3.3e-11 42.7 5.0 10.4 5 3 6 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 EEQ32059.1 - 1.1e-23 79.6 59.9 0.035 14.1 0.1 18.7 18 1 0 18 18 18 8 Leucine Rich Repeat Guanylate_cyc PF00211.15 EEQ32059.1 - 2.3e-21 76.0 0.0 8.2e-21 74.1 0.0 1.9 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_7 PF13504.1 EEQ32059.1 - 1.5e-11 42.5 59.0 0.57 10.6 0.2 16.4 17 0 0 17 17 16 5 Leucine rich repeat RA PF00788.18 EEQ32059.1 - 3.1e-08 33.9 0.0 8.5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ad_cyc_g-alpha PF08509.6 EEQ32059.1 - 6.9e-07 28.5 0.1 6.9e-07 28.5 0.1 2.8 3 0 0 3 3 2 1 Adenylate cyclase G-alpha binding domain LRR_5 PF13306.1 EEQ32059.1 - 6.7e-06 25.8 3.5 0.074 12.7 0.1 3.9 3 1 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EEQ32059.1 - 8.1e-06 25.3 54.3 1.6 9.0 0.0 15.6 17 2 2 19 19 17 3 Leucine Rich repeat LRR_9 PF14580.1 EEQ32059.1 - 1.3e-05 24.8 9.9 0.22 11.0 0.0 4.3 2 1 1 4 4 4 3 Leucine-rich repeat MSC PF09402.5 EEQ32060.1 - 9.2e-76 254.7 0.0 1.6e-74 250.5 0.0 2.1 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EEQ32060.1 - 2.6e-16 58.8 0.2 4.8e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain RseC_MucC PF04246.7 EEQ32060.1 - 0.2 11.2 0.7 0.82 9.2 0.1 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF3632 PF12311.3 EEQ32061.1 - 3.8e-20 72.4 0.3 8.3e-15 55.0 0.3 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF3632) UCH_1 PF13423.1 EEQ32062.1 - 8.8e-77 258.4 1.3 1.2e-76 258.0 0.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EEQ32062.1 - 7.5e-19 68.6 0.0 5.2e-17 62.6 0.0 2.6 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 EEQ32062.1 - 4.7e-05 22.6 0.0 0.00028 20.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase APH PF01636.18 EEQ32064.1 - 5.8e-11 42.5 0.0 2e-10 40.8 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ32064.1 - 0.021 14.3 0.0 0.068 12.7 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase NIF PF03031.13 EEQ32064.1 - 0.029 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase KH_1 PF00013.24 EEQ32065.1 - 1.5e-92 303.1 9.8 2.7e-12 46.1 0.0 13.2 13 1 0 13 13 13 9 KH domain KH_3 PF13014.1 EEQ32065.1 - 7.1e-65 213.8 17.1 2.5e-08 33.3 0.5 12.2 13 0 0 13 13 13 9 KH domain SLS PF14611.1 EEQ32065.1 - 7.8e-10 38.5 0.7 0.0072 15.7 0.0 6.2 5 1 1 6 6 6 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EEQ32065.1 - 9.8e-10 37.8 19.6 0.0036 16.8 0.4 7.8 6 1 1 7 7 7 4 KH domain BMC PF00936.14 EEQ32065.1 - 0.00016 21.2 1.5 0.046 13.4 0.1 4.5 4 0 0 4 4 4 1 BMC domain Pkinase PF00069.20 EEQ32066.1 - 2.8e-64 216.7 0.0 4.4e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32066.1 - 2e-41 141.7 0.0 3.4e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EEQ32066.1 - 1.7e-20 73.1 0.2 6.6e-20 71.2 0.1 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EEQ32066.1 - 6.6e-06 25.2 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ32066.1 - 0.022 14.4 0.1 0.2 11.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEQ32066.1 - 0.061 12.1 0.2 0.092 11.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EEQ32066.1 - 0.065 12.2 0.1 0.13 11.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VHS PF00790.14 EEQ32067.1 - 3.7e-32 110.8 1.0 6.7e-32 110.0 0.7 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EEQ32067.1 - 1.7e-17 62.5 0.1 1e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEQ32067.1 - 2.5e-16 58.9 0.2 6e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ32067.1 - 9.9e-14 50.5 0.1 2.7e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.15 EEQ32067.1 - 0.022 14.3 1.1 0.057 13.0 0.7 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif K_trans PF02705.11 EEQ32068.1 - 1.4e-181 604.5 21.3 1.6e-181 604.3 14.8 1.0 1 0 0 1 1 1 1 K+ potassium transporter WHIM3 PF15614.1 EEQ32068.1 - 0.18 11.6 0.0 0.57 10.0 0.0 1.7 1 1 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 Cyt-b5 PF00173.23 EEQ32069.1 - 1.3e-25 88.9 0.0 1.7e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ATPase_gene1 PF09527.5 EEQ32069.1 - 0.065 13.0 0.8 0.089 12.6 0.5 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) GTP_EFTU PF00009.22 EEQ32070.1 - 9.1e-49 165.4 0.0 1.5e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EEQ32070.1 - 8.2e-20 70.7 7.4 1.6e-19 69.8 5.1 1.4 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EEQ32070.1 - 7.7e-09 35.6 0.0 1.9e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEQ32070.1 - 1.7e-07 31.2 0.1 4.6e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ32070.1 - 6.8e-06 26.0 0.0 2.3e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEQ32070.1 - 0.006 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EEQ32070.1 - 0.0087 15.3 0.0 0.026 13.7 0.0 1.7 1 1 1 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.13 EEQ32070.1 - 0.032 13.5 0.1 0.36 10.1 0.1 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B HSP70 PF00012.15 EEQ32071.1 - 1.3e-263 875.4 11.7 1.5e-263 875.2 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ32071.1 - 2e-18 66.0 1.3 2.9e-17 62.2 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EEQ32071.1 - 0.0001 21.5 2.6 0.16 10.9 0.1 3.3 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase DDR PF08841.5 EEQ32071.1 - 0.0029 16.4 0.2 0.025 13.4 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EEQ32071.1 - 0.044 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EEQ32071.1 - 5.9 6.7 9.4 4.9 7.0 0.1 4.0 4 1 0 4 4 4 0 Cell division protein FtsA UCH PF00443.24 EEQ32072.1 - 3.1e-59 200.2 0.1 5e-59 199.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ32072.1 - 1.2e-24 87.2 0.1 2.3e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EEQ32072.1 - 0.0034 17.6 0.0 0.0084 16.4 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain VHS PF00790.14 EEQ32073.1 - 1.8e-42 144.3 3.3 6.4e-42 142.5 0.2 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EEQ32073.1 - 1.7e-16 59.8 1.4 2.9e-16 59.0 1.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EEQ32073.1 - 2.2e-06 26.7 6.0 0.0043 16.4 0.8 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 EEQ32073.1 - 0.02 14.2 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 EEQ32073.1 - 0.049 13.5 0.3 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger TCO89 PF10452.4 EEQ32075.1 - 0.015 14.2 0.3 0.015 14.2 0.2 4.1 2 2 2 4 4 4 0 TORC1 subunit TCO89 RCC1 PF00415.13 EEQ32076.1 - 4.3e-23 81.2 0.2 1.3e-07 31.7 0.0 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEQ32076.1 - 2.2e-12 46.2 4.4 6.2e-08 32.0 0.1 4.3 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EEQ32076.1 - 1.4e-10 41.1 0.1 1.2e-06 28.5 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 EEQ32076.1 - 1.6e-06 28.4 1.2 0.00075 19.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ32076.1 - 0.00037 20.4 0.1 0.026 14.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EEQ32076.1 - 0.0037 17.5 0.1 1.3 9.3 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ32076.1 - 0.072 12.9 0.2 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat ATG13 PF10033.4 EEQ32077.1 - 3.4e-35 121.5 0.0 1.2e-25 90.3 0.0 2.3 1 1 1 2 2 2 2 Autophagy-related protein 13 adh_short PF00106.20 EEQ32080.1 - 7e-17 61.8 0.0 9.8e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ32080.1 - 8.9e-10 38.5 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ32080.1 - 4.7e-08 32.7 0.0 6.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEQ32080.1 - 0.00013 20.9 0.1 0.00018 20.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EEQ32080.1 - 0.0013 18.8 0.1 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 EEQ32080.1 - 0.017 14.0 0.1 0.04 12.8 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein NUMOD1 PF07453.8 EEQ32080.1 - 0.022 14.5 0.1 0.24 11.3 0.1 2.5 2 0 0 2 2 2 0 NUMOD1 domain DUF2236 PF09995.4 EEQ32082.1 - 8.4e-10 38.3 0.0 1.7e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Methyltransf_26 PF13659.1 EEQ32083.1 - 1.5e-07 31.4 0.0 5e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ32083.1 - 1.7e-05 25.3 0.1 0.00011 22.7 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain AMP-binding_C PF13193.1 EEQ32083.1 - 3.8e-05 24.5 0.1 0.0037 18.1 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.1 EEQ32083.1 - 0.00023 21.4 0.0 0.00068 19.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ32083.1 - 0.00023 20.8 0.0 0.00054 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ32083.1 - 0.0004 20.1 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ32083.1 - 0.0033 17.8 0.0 0.0093 16.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ32083.1 - 0.0077 16.7 0.0 0.031 14.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ32083.1 - 0.014 14.8 0.1 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FA_hydroxylase PF04116.8 EEQ32084.1 - 5.7e-15 55.7 18.9 5.7e-15 55.7 13.1 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1993 PF09351.5 EEQ32085.1 - 3.8e-07 30.1 0.0 5.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) CFC PF09443.5 EEQ32086.1 - 0.27 10.8 4.5 0.31 10.6 1.7 2.0 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Trp_DMAT PF11991.3 EEQ32087.1 - 1.9e-92 310.2 0.0 1.1e-91 307.7 0.0 1.8 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase Condensation PF00668.15 EEQ32088.1 - 3.1e-90 302.0 0.0 1.6e-31 109.2 0.0 3.4 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 EEQ32088.1 - 2e-81 273.5 0.0 6.3e-81 271.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EEQ32088.1 - 1.1e-66 224.8 2.8 2.1e-66 224.0 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ32088.1 - 2.8e-53 181.3 1.5 5.1e-53 180.4 1.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EEQ32088.1 - 6.7e-50 169.2 0.1 2.2e-49 167.5 0.0 2.0 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EEQ32088.1 - 8.7e-43 146.5 0.3 8.7e-43 146.5 0.2 2.8 3 0 0 3 3 3 1 Polyketide synthase dehydratase adh_short PF00106.20 EEQ32088.1 - 4.5e-42 143.7 0.2 1.9e-41 141.7 0.0 2.3 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEQ32088.1 - 2.6e-32 111.1 0.0 1.4e-31 108.8 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EEQ32088.1 - 3.9e-24 84.6 0.8 4.4e-11 42.8 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EEQ32088.1 - 1.4e-18 67.2 0.0 6.9e-18 64.9 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EEQ32088.1 - 3.5e-15 55.7 0.0 1.4e-14 53.7 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EEQ32088.1 - 1e-12 48.0 0.0 4.7e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ32088.1 - 2.3e-09 37.6 0.0 9.7e-09 35.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EEQ32088.1 - 1.6e-08 34.2 0.2 3.4e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 EEQ32088.1 - 2.4e-08 33.7 0.0 6.2e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EEQ32088.1 - 2.9e-06 28.1 0.2 5e-05 24.2 0.0 3.2 3 0 0 3 3 2 1 Zinc-binding dehydrogenase AMP-binding_C PF13193.1 EEQ32088.1 - 1.9e-05 25.5 0.0 0.00013 22.8 0.0 2.6 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Ubie_methyltran PF01209.13 EEQ32088.1 - 5.5e-05 22.4 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EEQ32088.1 - 6.2e-05 23.5 0.0 0.00034 21.1 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EEQ32088.1 - 0.0025 17.2 0.0 0.0052 16.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 EEQ32088.1 - 0.004 16.1 0.1 0.0086 15.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 EEQ32088.1 - 0.019 13.8 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HNH_2 PF13391.1 EEQ32089.1 - 1.9e-06 27.5 0.0 4.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease FAD_binding_4 PF01565.18 EEQ32090.1 - 2e-24 85.6 0.2 3.9e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ32090.1 - 3.8e-05 23.5 0.0 8.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like SET PF00856.23 EEQ32091.1 - 5.2e-14 52.8 0.0 6.9e-13 49.2 0.0 2.7 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 EEQ32091.1 - 2e-12 46.5 2.1 2e-07 30.5 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EEQ32091.1 - 2.4e-05 23.8 2.2 0.042 13.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ32091.1 - 2.6e-05 24.7 0.8 0.024 15.2 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ32091.1 - 0.002 17.6 1.8 0.48 10.1 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ32091.1 - 0.0026 17.4 0.3 0.31 10.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ32091.1 - 0.0034 17.2 1.2 0.0094 15.8 0.8 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Sulfotransfer_3 PF13469.1 EEQ32092.1 - 0.023 15.6 0.0 0.063 14.2 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase family Herpes_ori_bp PF02399.10 EEQ32092.1 - 0.068 11.1 0.0 0.079 10.8 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein NUC153 PF08159.7 EEQ32093.1 - 3e-10 39.4 0.3 6.5e-10 38.4 0.2 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EEQ32093.1 - 2.8e-05 23.8 0.1 0.23 11.4 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Med13_C PF06333.7 EEQ32096.1 - 6.2e-81 272.0 0.6 1.1e-80 271.3 0.4 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EEQ32096.1 - 6.7e-30 104.0 0.0 6.7e-30 104.0 0.0 2.1 2 1 0 2 2 2 1 Mediator complex subunit 13 N-terminal NPIP PF06409.6 EEQ32096.1 - 0.014 14.1 0.2 0.024 13.3 0.1 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) p450 PF00067.17 EEQ32097.1 - 4.9e-66 223.1 0.0 6.2e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEQ32098.1 - 4.2e-34 117.8 0.0 5.8e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L33 PF00471.15 EEQ32099.1 - 3.7e-05 23.8 0.0 4.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 SecY PF00344.15 EEQ32101.1 - 0.74 8.6 7.1 0.64 8.8 2.6 2.0 2 0 0 2 2 2 0 SecY translocase Shisa PF13908.1 EEQ32102.1 - 0.018 15.2 0.1 0.025 14.7 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Cellulase PF00150.13 EEQ32103.1 - 4e-08 32.8 4.2 4.8e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 EEQ32103.1 - 0.072 13.4 2.2 3.4 8.1 0.0 3.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 EEQ32104.1 - 8.5e-53 179.1 0.0 1.3e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32104.1 - 3.4e-28 98.4 0.0 5e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ32104.1 - 2e-05 23.7 0.0 3.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ32104.1 - 0.007 16.1 1.5 0.013 15.2 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ32104.1 - 0.026 13.5 0.1 0.043 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EEQ32104.1 - 0.23 10.2 0.1 0.34 9.7 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Retinal PF15449.1 EEQ32104.1 - 0.81 7.2 22.8 1 6.9 15.8 1.0 1 0 0 1 1 1 0 Retinal protein Macoilin PF09726.4 EEQ32104.1 - 5.1 5.2 6.1 6.8 4.8 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein SNF2_N PF00176.18 EEQ32105.1 - 1.6e-73 247.1 0.0 6.7e-73 245.0 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ32105.1 - 7.8e-11 41.6 0.0 2.7e-10 39.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 EEQ32105.1 - 0.0014 18.0 1.7 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 DEAD_2 Senescence_reg PF04520.8 EEQ32105.1 - 0.055 13.9 15.0 0.037 14.5 1.3 4.2 3 1 0 3 3 3 0 Senescence regulator PALP PF00291.20 EEQ32107.1 - 7.9e-52 176.3 0.2 9.7e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 EEQ32108.1 - 4.5e-22 78.2 74.5 1.2e-21 76.8 35.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EEQ32109.1 - 3.8e-32 111.3 26.9 5.1e-17 61.6 7.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ32109.1 - 3.7e-07 29.0 22.0 4.5e-06 25.5 15.3 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EEQ32109.1 - 9.3e-06 24.2 24.4 0.0041 15.5 5.2 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EEQ32109.1 - 0.0051 16.5 7.2 0.014 15.1 0.6 2.9 3 0 0 3 3 3 1 MFS_1 like family OATP PF03137.15 EEQ32109.1 - 0.017 13.2 7.1 0.4 8.6 0.1 3.7 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EEQ32109.1 - 0.12 10.4 15.6 0.0085 14.2 2.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector SIR2 PF02146.12 EEQ32110.1 - 8.3e-38 129.8 0.0 1.3e-36 125.9 0.0 2.0 1 1 0 1 1 1 1 Sir2 family PhnA_Zn_Ribbon PF08274.7 EEQ32110.1 - 1.6 8.6 5.2 1.2 8.9 0.8 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Pyridox_ox_2 PF12900.2 EEQ32111.1 - 1.7e-37 128.4 0.0 2.6e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.20 EEQ32112.1 - 1.3e-18 67.0 0.5 1.8e-18 66.6 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32112.1 - 3e-16 59.2 0.1 3.9e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ32112.1 - 9.5e-05 21.4 0.0 0.0002 20.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EEQ32112.1 - 0.00085 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EEQ32112.1 - 0.0019 17.3 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ32112.1 - 0.062 13.0 0.6 0.16 11.7 0.4 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family ADH_zinc_N PF00107.21 EEQ32114.1 - 5.7e-23 80.8 0.0 1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ32114.1 - 4.7e-11 43.6 0.0 3e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ32114.1 - 5.6e-08 32.5 0.0 1.8e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FR47 PF08445.5 EEQ32115.1 - 7.5e-09 35.2 0.0 0.00019 21.1 0.0 2.9 2 1 1 3 3 3 2 FR47-like protein Acetyltransf_3 PF13302.1 EEQ32115.1 - 3.5e-07 30.4 0.0 1.2e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ32115.1 - 2.2e-05 24.3 0.1 0.00015 21.7 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEQ32115.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ32115.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_M24 PF00557.19 EEQ32116.1 - 7.3e-42 143.2 0.0 1.8e-41 142.0 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 EEQ32116.1 - 4e-35 120.1 0.0 7.4e-35 119.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 EEQ32117.1 - 9.2e-36 122.3 0.0 1.7e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EEQ32117.1 - 2e-21 75.4 1.5 3.6e-21 74.5 1.0 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EEQ32117.1 - 0.0002 21.4 0.0 0.00057 19.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEQ32117.1 - 0.0087 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain Pantoate_transf PF02548.10 EEQ32118.1 - 1.6e-105 351.9 2.4 1.9e-105 351.6 1.7 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EEQ32118.1 - 1.2e-10 41.0 2.0 2.8e-10 39.8 1.4 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Peptidase_M20 PF01546.23 EEQ32118.1 - 0.15 11.5 1.0 8.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 APG12 PF04110.8 EEQ32119.1 - 2.4e-27 94.9 0.0 3.6e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EEQ32119.1 - 0.033 14.1 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like HNH_2 PF13391.1 EEQ32120.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease DUF4267 PF14087.1 EEQ32121.1 - 5.2e-22 77.5 3.2 6e-22 77.3 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DPM2 PF07297.7 EEQ32121.1 - 0.23 11.7 1.9 1.8 8.9 0.4 2.5 2 1 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Pkinase PF00069.20 EEQ32122.1 - 2.4e-06 26.8 0.0 3.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ32122.1 - 0.0022 17.7 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EEQ32122.1 - 0.003 16.6 0.0 0.0064 15.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ32122.1 - 0.15 11.1 0.1 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SBP_bac_8 PF13416.1 EEQ32122.1 - 0.23 11.1 0.0 0.33 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Phtf-FEM1B_bdg PF12129.3 EEQ32123.1 - 0.17 11.2 0.4 0.28 10.5 0.3 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor UQ_con PF00179.21 EEQ32124.1 - 1.5e-35 121.6 0.1 1.9e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.1 EEQ32126.1 - 1.4e-18 66.9 0.9 2.5e-18 66.1 0.0 1.8 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2011 PF09428.5 EEQ32127.1 - 7.3e-43 145.5 5.3 7.3e-43 145.5 3.7 1.5 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) DDHD PF02862.12 EEQ32127.1 - 10 5.8 9.8 3.1 7.5 0.9 2.1 2 0 0 2 2 2 0 DDHD domain D123 PF07065.9 EEQ32129.1 - 1.2e-05 24.5 0.0 6.8e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 D123 DUF4343 PF14243.1 EEQ32129.1 - 0.0023 17.7 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) Sulfotransfer_3 PF13469.1 EEQ32130.1 - 0.057 14.3 0.1 0.31 11.9 0.1 1.9 1 1 0 1 1 1 0 Sulfotransferase family 3Beta_HSD PF01073.14 EEQ32131.1 - 5.8e-48 163.0 0.0 7.4e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEQ32131.1 - 3e-29 102.1 0.0 4e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEQ32131.1 - 3.5e-12 45.7 0.5 9.3e-11 41.1 0.0 2.0 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EEQ32131.1 - 1.9e-08 33.5 0.0 2.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEQ32131.1 - 3.4e-07 30.4 0.0 5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EEQ32131.1 - 0.0046 16.6 0.4 0.04 13.5 0.3 2.2 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEQ32131.1 - 0.005 15.7 0.4 0.067 12.0 0.3 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EEQ32131.1 - 0.0056 16.6 0.4 0.06 13.2 0.2 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Cerato-platanin PF07249.7 EEQ32132.1 - 2.4e-43 146.9 0.3 2.9e-43 146.6 0.2 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EEQ32132.1 - 0.015 14.9 0.1 0.021 14.4 0.1 1.5 1 1 0 1 1 1 0 Barwin family Choline_kinase PF01633.15 EEQ32133.1 - 8.5e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EEQ32133.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ32133.1 - 0.04 12.5 0.0 0.057 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEQ32133.1 - 0.08 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase MFS_1 PF07690.11 EEQ32134.1 - 1.9e-46 158.4 45.9 1.9e-46 158.4 31.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ32134.1 - 3.7e-15 55.4 15.4 3.7e-15 55.4 10.7 3.5 3 2 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EEQ32134.1 - 3.8e-08 32.0 22.3 2e-07 29.6 15.4 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Flavoprotein PF02441.14 EEQ32135.1 - 1.4e-10 40.8 0.0 2.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Ank_2 PF12796.2 EEQ32135.1 - 0.086 13.1 0.0 2.5 8.5 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ32135.1 - 0.11 13.0 0.3 39 4.9 0.0 3.9 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Peptidase_S8 PF00082.17 EEQ32136.1 - 4.6e-44 150.6 11.7 6.3e-44 150.2 8.1 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ32136.1 - 4.6e-11 43.1 0.0 9.8e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 p450 PF00067.17 EEQ32137.1 - 1.3e-64 218.4 0.0 1.6e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_11 PF13720.1 EEQ32137.1 - 0.023 14.9 0.1 8.5 6.6 0.0 2.5 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Asparaginase_2 PF01112.13 EEQ32138.1 - 3e-38 131.3 0.0 2.4e-37 128.3 0.0 2.4 1 1 0 1 1 1 1 Asparaginase Tim17 PF02466.14 EEQ32139.1 - 1.2e-28 99.6 5.7 1.6e-28 99.3 3.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TraQ PF09679.5 EEQ32140.1 - 0.036 13.9 0.4 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Dsh_C PF12316.3 EEQ32140.1 - 3.3 7.7 18.5 0.78 9.8 5.5 2.3 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Peptidase_M20 PF01546.23 EEQ32141.1 - 1.1e-22 80.5 0.0 2.4e-22 79.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EEQ32141.1 - 3.3e-20 71.1 5.3 3.5e-05 23.5 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.9 EEQ32141.1 - 7.2e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF747 PF05346.6 EEQ32142.1 - 4.2e-85 285.7 0.0 2.7e-50 171.3 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic membrane protein family TMEM154 PF15102.1 EEQ32142.1 - 0.25 11.0 0.0 0.25 11.0 0.0 2.5 3 0 0 3 3 3 0 TMEM154 protein family APH PF01636.18 EEQ32146.1 - 3.6e-22 79.2 0.1 1.3e-21 77.4 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ32146.1 - 0.11 11.5 0.1 11 5.0 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M43 PF05572.8 EEQ32147.1 - 6.2e-17 61.6 0.2 8.9e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EEQ32147.1 - 2.3e-06 28.1 1.0 1.3e-05 25.7 0.7 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EEQ32147.1 - 7.9e-06 25.9 1.1 1.7e-05 24.8 0.8 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EEQ32147.1 - 0.00012 22.1 1.9 0.00013 22.0 0.7 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EEQ32147.1 - 0.00024 20.7 0.7 0.002 17.6 0.2 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EEQ32147.1 - 0.0062 16.2 0.0 0.0083 15.8 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EEQ32147.1 - 0.015 14.1 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.19 EEQ32147.1 - 0.11 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M7 PF02031.11 EEQ32147.1 - 0.14 11.8 3.6 0.089 12.5 0.9 1.8 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family ERG4_ERG24 PF01222.12 EEQ32148.1 - 2e-150 501.1 16.1 2.2e-150 500.9 11.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EEQ32148.1 - 0.00063 19.8 0.6 0.0093 16.0 0.0 3.2 2 0 0 2 2 2 1 Phospholipid methyltransferase FAD_binding_4 PF01565.18 EEQ32149.1 - 1.6e-18 66.5 0.6 3.1e-18 65.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ32149.1 - 0.00013 21.7 0.1 0.00027 20.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DHquinase_I PF01487.10 EEQ32149.1 - 0.04 13.5 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Type I 3-dehydroquinase Ank_2 PF12796.2 EEQ32152.1 - 3.5e-70 232.3 15.3 9.5e-19 67.5 0.2 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ32152.1 - 1.8e-47 156.8 6.0 1.5e-07 30.8 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.1 EEQ32152.1 - 2.9e-43 141.5 2.4 2.1e-05 24.3 0.0 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 EEQ32152.1 - 1.2e-41 140.3 3.3 1.8e-10 40.9 0.0 6.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ32152.1 - 3.1e-34 116.2 11.4 6.1e-09 35.8 0.0 6.8 3 2 3 7 7 7 6 Ankyrin repeats (many copies) GATase_7 PF13537.1 EEQ32152.1 - 0.0033 17.1 0.0 23 4.7 0.0 4.2 4 1 1 5 5 5 0 Glutamine amidotransferase domain DUF3868 PF12984.2 EEQ32152.1 - 0.025 14.0 0.0 12 5.4 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3868) Pkinase PF00069.20 EEQ32153.1 - 2.6e-05 23.5 0.1 5.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ32153.1 - 0.0001 22.1 0.0 0.0001 22.1 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 EEQ32153.1 - 0.001 18.8 0.0 1.2 9.0 0.0 2.5 1 1 1 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.15 EEQ32153.1 - 0.0039 16.7 1.2 0.0051 16.3 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase CDC45 PF02724.9 EEQ32153.1 - 4.2 5.2 11.9 6.4 4.6 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 EEQ32153.1 - 5.9 4.4 7.9 8.3 3.9 5.5 1.1 1 0 0 1 1 1 0 Ycf1 DUF3584 PF12128.3 EEQ32153.1 - 9.3 3.4 19.5 13 2.9 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2094 PF09867.4 EEQ32154.1 - 0.12 12.2 0.6 0.28 11.0 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2094) AIF_C PF14721.1 EEQ32154.1 - 1.8 8.8 5.5 3.9 7.7 3.8 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term F-box-like PF12937.2 EEQ32156.1 - 1.5e-07 30.9 0.9 2e-07 30.6 0.1 1.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEQ32156.1 - 0.0026 17.3 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain VMA21 PF09446.5 EEQ32157.1 - 7.5e-11 41.7 2.9 9.7e-11 41.4 2.0 1.2 1 0 0 1 1 1 1 VMA21-like domain Ribosomal_L35Ae PF01247.13 EEQ32159.1 - 8e-42 140.9 1.1 8.9e-42 140.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EEQ32159.1 - 0.0024 17.7 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain SRF-TF PF00319.13 EEQ32160.1 - 1.2e-23 82.0 0.2 2e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3602 PF12223.3 EEQ32162.1 - 4.2e-10 39.8 3.9 1.5e-06 28.5 0.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) CBM_14 PF01607.19 EEQ32164.1 - 7.1e-08 32.2 0.2 1e-07 31.7 0.2 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Peptidase_S64 PF08192.6 EEQ32165.1 - 0.00017 20.0 0.0 0.0037 15.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S64 DUF2839 PF10999.3 EEQ32166.1 - 2.7 8.0 5.7 6.6 6.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) COesterase PF00135.23 EEQ32167.1 - 2.2e-101 340.1 0.0 3e-101 339.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ32167.1 - 1.7e-08 34.3 0.0 5.8e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ32167.1 - 0.0032 17.2 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ32167.1 - 0.12 11.5 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-actin_cap_A PF01267.12 EEQ32168.1 - 4.3e-87 291.6 0.1 1.9e-82 276.3 0.0 2.0 2 0 0 2 2 2 2 F-actin capping protein alpha subunit Macoilin PF09726.4 EEQ32170.1 - 1.8 6.7 7.0 2.2 6.4 4.8 1.2 1 0 0 1 1 1 0 Transmembrane protein PAP2 PF01569.16 EEQ32171.1 - 7.1e-25 87.1 0.2 7.1e-25 87.1 0.1 1.8 1 1 1 2 2 2 1 PAP2 superfamily DUF2418 PF10332.4 EEQ32171.1 - 0.18 12.1 3.4 0.31 11.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) Sec62 PF03839.11 EEQ32171.1 - 0.2 11.0 3.2 0.29 10.5 2.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Med7 PF05983.6 EEQ32172.1 - 5.9e-49 165.9 0.0 7.1e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 MED7 protein TT_ORF2 PF02957.10 EEQ32172.1 - 0.22 12.2 2.3 0.48 11.1 0.5 2.0 2 0 0 2 2 2 0 TT viral ORF2 HEAT PF02985.17 EEQ32174.1 - 3.3e-21 73.4 6.2 8.3e-06 25.4 0.1 9.5 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 EEQ32174.1 - 2.4e-20 72.6 8.9 2.4e-05 24.5 0.0 8.5 5 3 3 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 EEQ32174.1 - 6.7e-18 64.6 9.1 0.00023 21.5 0.0 11.8 11 3 3 14 14 13 5 HEAT-like repeat Cnd1 PF12717.2 EEQ32174.1 - 2.8e-08 33.8 1.5 0.31 10.8 0.3 4.6 4 2 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EEQ32174.1 - 6.7e-08 32.8 0.0 3 8.2 0.0 6.5 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EEQ32174.1 - 1.4e-07 30.6 4.2 0.00037 19.3 0.0 4.0 3 2 3 6 6 6 2 RNAPII transcription regulator C-terminal UME PF08064.8 EEQ32174.1 - 1.6e-07 31.2 0.1 0.32 10.9 0.0 5.7 5 1 1 6 6 6 2 UME (NUC010) domain CLASP_N PF12348.3 EEQ32174.1 - 3.8e-06 26.4 0.0 0.018 14.4 0.0 4.0 4 0 0 4 4 4 2 CLASP N terminal IBN_N PF03810.14 EEQ32174.1 - 3e-05 23.8 0.5 3e-05 23.8 0.3 3.6 5 0 0 5 5 5 1 Importin-beta N-terminal domain Arm PF00514.18 EEQ32174.1 - 0.00042 20.0 0.0 33 4.5 0.0 5.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EEQ32174.1 - 0.00047 18.6 0.7 0.39 8.9 0.0 3.2 3 1 0 3 3 3 2 Adaptin N terminal region Cohesin_HEAT PF12765.2 EEQ32174.1 - 0.0083 16.0 0.0 0.31 11.0 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF1839 PF08893.5 EEQ32174.1 - 0.074 12.0 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Patched PF02460.13 EEQ32175.1 - 8.5e-76 255.5 10.6 7.1e-75 252.4 7.4 2.0 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EEQ32175.1 - 3.4e-52 175.9 6.0 3.4e-52 175.9 4.2 2.9 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EEQ32175.1 - 5.9e-07 28.5 9.8 5.9e-07 28.5 6.8 3.4 3 1 0 3 3 3 1 MMPL family Folate_rec PF03024.9 EEQ32175.1 - 0.0051 16.4 4.2 0.011 15.4 2.9 1.4 1 0 0 1 1 1 1 Folate receptor family DUF2433 PF10360.4 EEQ32176.1 - 1.9e-53 180.2 0.0 3.1e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EEQ32176.1 - 0.001 18.9 0.0 0.0033 17.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEQ32176.1 - 0.0013 18.1 0.0 0.0033 16.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAP1 PF08601.5 EEQ32177.1 - 2e-57 195.4 34.3 2.3e-55 188.7 19.1 3.6 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EEQ32177.1 - 4.8e-08 32.8 9.0 1.1e-07 31.7 6.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF16 PF01519.11 EEQ32177.1 - 0.065 13.4 2.9 0.13 12.4 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 IncA PF04156.9 EEQ32177.1 - 0.29 10.6 6.8 0.49 9.9 4.7 1.3 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 EEQ32177.1 - 0.34 11.3 2.6 0.83 10.0 1.8 1.7 1 0 0 1 1 1 0 SlyX bZIP_Maf PF03131.12 EEQ32177.1 - 4.3 7.6 17.0 0.19 12.0 7.3 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Adeno_PIX PF03955.9 EEQ32177.1 - 9.6 6.7 8.7 0.59 10.6 0.9 2.5 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF4537 PF15057.1 EEQ32178.1 - 0.0032 17.2 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.6 EEQ32178.1 - 0.02 14.5 0.5 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 SGF29 tudor-like domain PWWP PF00855.12 EEQ32178.1 - 0.051 13.7 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 PWWP domain Fis1_TPR_C PF14853.1 EEQ32178.1 - 0.17 11.7 0.2 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TRAUB PF08164.7 EEQ32179.1 - 8.6e-33 112.3 0.1 2.7e-32 110.7 0.0 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EEQ32179.1 - 4.9e-31 107.5 1.3 4.9e-31 107.5 0.9 2.2 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor RRN3 PF05327.6 EEQ32179.1 - 2.7 5.9 8.6 4.6 5.2 6.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ParA PF10609.4 EEQ32180.1 - 7e-33 112.3 0.4 1.7e-32 111.1 0.0 1.8 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EEQ32180.1 - 3.5e-17 62.4 0.0 5.3e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEQ32180.1 - 1.9e-09 37.6 0.1 1.4e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EEQ32180.1 - 4.4e-06 25.9 0.1 6.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EEQ32180.1 - 0.00016 20.8 0.4 0.0013 17.8 0.2 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 EEQ32180.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EEQ32180.1 - 0.073 12.2 0.0 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 EEQ32180.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein Abhydrolase_3 PF07859.8 EEQ32181.1 - 2.6e-15 56.5 0.1 2.1e-05 24.2 0.0 3.4 3 0 0 3 3 3 3 alpha/beta hydrolase fold DUF2424 PF10340.4 EEQ32181.1 - 0.00057 18.6 0.0 0.79 8.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Pkinase PF00069.20 EEQ32182.1 - 3.4e-12 46.0 0.0 7.5e-12 44.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32182.1 - 0.0041 16.2 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WGG PF10273.4 EEQ32183.1 - 1.8e-29 101.6 0.1 3.7e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 EEQ32183.1 - 0.026 14.5 0.2 0.052 13.5 0.2 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Herpes_UL49_2 PF04823.7 EEQ32183.1 - 0.048 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Nucleoplasmin PF03066.10 EEQ32183.1 - 0.68 9.4 4.8 1.1 8.7 3.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EEQ32183.1 - 3.2 6.9 5.5 4 6.6 3.8 1.1 1 0 0 1 1 1 0 NOA36 protein Tht1 PF04163.7 EEQ32184.1 - 5.5e-07 28.3 9.1 8.4e-07 27.7 6.3 1.2 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein Surfac_D-trimer PF09006.6 EEQ32184.1 - 0.065 12.9 0.2 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Scaffolding_pro PF11418.3 EEQ32184.1 - 0.59 10.4 4.2 13 6.1 0.0 3.6 1 1 3 4 4 4 0 Phi29 scaffolding protein Ribosomal_L6 PF00347.18 EEQ32185.1 - 1.5e-23 83.0 0.0 2.1e-12 47.3 0.0 2.7 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 EEQ32186.1 - 1.2e-52 178.8 0.4 2.3e-52 177.9 0.3 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.14 EEQ32187.1 - 7.1e-27 93.7 0.0 1.2e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 VHS domain ENTH PF01417.15 EEQ32187.1 - 0.00066 19.5 0.0 0.0019 18.0 0.0 1.7 2 0 0 2 2 2 1 ENTH domain GAT PF03127.9 EEQ32187.1 - 0.00072 19.4 0.3 0.0014 18.5 0.2 1.5 1 0 0 1 1 1 1 GAT domain APH PF01636.18 EEQ32188.1 - 2.3e-08 34.0 0.0 3.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ32188.1 - 0.013 14.1 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF3082 PF11282.3 EEQ32188.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) Csm1 PF12539.3 EEQ32188.1 - 0.022 15.2 0.1 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Chromosome segregation protein Csm1/Pcs1 Choline_kinase PF01633.15 EEQ32188.1 - 0.093 12.2 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF2945 PF11160.3 EEQ32189.1 - 2.1e-22 78.6 0.1 2.7e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) CP2 PF04516.10 EEQ32191.1 - 4.3e-69 232.1 0.0 6.4e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Pkinase PF00069.20 EEQ32192.1 - 1.7e-31 109.3 0.0 2.9e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EEQ32192.1 - 1.6e-21 76.4 0.0 1.5e-10 41.3 0.0 3.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.12 EEQ32192.1 - 2e-14 53.2 0.0 3.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.25 EEQ32192.1 - 4e-14 51.6 4.3 0.0044 16.7 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EEQ32192.1 - 6.6e-13 47.5 0.9 0.12 12.7 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EEQ32192.1 - 2.2e-11 43.9 0.9 0.077 13.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ32192.1 - 5.6e-11 42.3 0.5 0.16 12.2 0.0 5.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Kinase-like PF14531.1 EEQ32192.1 - 0.08 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_18 PF00704.23 EEQ32193.1 - 1.8e-43 149.3 0.8 2.9e-43 148.6 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEQ32193.1 - 5.5e-11 42.1 0.0 0.00011 22.0 0.0 2.9 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EEQ32193.1 - 0.00037 20.4 6.7 0.00037 20.4 4.6 2.8 2 0 0 2 2 2 1 Chitin recognition protein DUF3142 PF11340.3 EEQ32193.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) Aspzincin_M35 PF14521.1 EEQ32194.1 - 0.083 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Amb_V_allergen PF03913.8 EEQ32194.1 - 0.36 10.6 1.8 0.54 10.0 0.0 2.1 3 0 0 3 3 3 0 Amb V Allergen LysM PF01476.15 EEQ32195.1 - 2.8e-17 62.3 2.4 2e-06 27.6 0.0 4.9 3 2 2 5 5 5 3 LysM domain DEAD PF00270.24 EEQ32196.1 - 1.1e-43 148.7 0.0 3.1e-43 147.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ32196.1 - 5e-22 77.5 0.0 1.1e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ32196.1 - 0.00063 18.6 0.0 0.0019 17.0 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EEQ32196.1 - 0.0038 17.3 0.5 0.09 12.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 EEQ32196.1 - 0.0064 16.3 0.5 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AhpC-TSA PF00578.16 EEQ32196.1 - 0.063 12.9 0.1 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 AhpC/TSA family Senescence_reg PF04520.8 EEQ32196.1 - 1 9.8 8.6 0.035 14.6 0.9 2.3 2 1 0 2 2 2 0 Senescence regulator FAD_binding_1 PF00667.15 EEQ32197.1 - 1.8e-54 184.4 0.0 2.7e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEQ32197.1 - 5.1e-12 46.3 0.0 1.6e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Bunya_G1 PF03557.10 EEQ32197.1 - 0.5 8.0 0.0 0.73 7.5 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 Cast PF10174.4 EEQ32199.1 - 0.0041 15.2 3.7 0.0041 15.2 2.6 1.3 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone GAS PF13851.1 EEQ32199.1 - 0.0048 16.1 3.7 0.0062 15.7 2.6 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Fmp27_WPPW PF10359.4 EEQ32199.1 - 0.025 13.0 2.2 0.029 12.7 1.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.17 EEQ32199.1 - 0.047 13.7 2.6 0.058 13.4 1.8 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spc97_Spc98 PF04130.8 EEQ32199.1 - 0.081 11.2 0.1 0.087 11.1 0.1 1.0 1 0 0 1 1 1 0 Spc97 / Spc98 family DUF641 PF04859.7 EEQ32199.1 - 0.4 10.4 3.9 0.68 9.6 2.7 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) HNH_2 PF13391.1 EEQ32200.1 - 1.5e-17 63.1 0.1 3e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Peptidase_C1 PF00112.18 EEQ32200.1 - 0.042 13.7 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Papain family cysteine protease Proteasome PF00227.21 EEQ32201.1 - 1.5e-60 203.7 0.1 1.8e-60 203.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEQ32201.1 - 2.9e-14 52.0 0.4 6.9e-14 50.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EEQ32201.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.14 EEQ32202.1 - 1.5e-10 40.8 4.9 3.4e-09 36.4 0.1 3.4 3 0 0 3 3 3 2 FF domain WW PF00397.21 EEQ32202.1 - 3.5e-08 33.1 8.0 6.6e-08 32.2 2.6 2.6 2 0 0 2 2 2 1 WW domain Seryl_tRNA_N PF02403.17 EEQ32203.1 - 0.042 13.8 3.4 0.11 12.5 2.3 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TFIIA PF03153.8 EEQ32203.1 - 0.081 12.8 10.9 0.12 12.2 7.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4047 PF13256.1 EEQ32203.1 - 0.1 12.5 0.5 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DASH_Dam1 PF08653.5 EEQ32203.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF3188 PF11384.3 EEQ32204.1 - 4.1 7.0 4.8 0.74 9.4 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Pkinase PF00069.20 EEQ32205.1 - 1.6e-30 106.1 0.0 2.3e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32205.1 - 1.5e-19 70.1 0.0 2.1e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EEQ32205.1 - 9.4e-07 28.8 0.5 8.2e-06 25.8 0.1 2.5 3 0 0 3 3 3 1 FHA domain Kinase-like PF14531.1 EEQ32205.1 - 0.015 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TFIIS_M PF07500.9 EEQ32206.1 - 1.8e-20 73.1 0.0 3.7e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EEQ32206.1 - 5.1e-19 68.9 0.0 1e-18 67.9 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EEQ32206.1 - 2.9e-10 39.6 11.5 5.1e-10 38.8 7.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEQ32206.1 - 0.023 14.0 4.5 0.043 13.1 3.1 1.5 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.1 EEQ32206.1 - 0.031 14.5 4.5 0.11 12.6 3.1 2.0 1 1 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Terminase_GpA PF05876.7 EEQ32206.1 - 0.093 11.0 5.0 0.15 10.3 3.5 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) LUC7 PF03194.10 EEQ32207.1 - 3.5e-71 239.7 0.1 4.3e-71 239.4 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.6 EEQ32207.1 - 0.06 12.0 0.3 0.087 11.5 0.2 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DASH_Duo1 PF08651.5 EEQ32207.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 AAA_13 PF13166.1 EEQ32207.1 - 0.12 10.8 0.5 0.15 10.4 0.3 1.1 1 0 0 1 1 1 0 AAA domain Gpi16 PF04113.9 EEQ32208.1 - 8.8e-236 783.3 0.0 1.1e-235 782.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component TFIIA PF03153.8 EEQ32209.1 - 0.16 11.8 13.0 0.22 11.3 9.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HECT PF00632.20 EEQ32210.1 - 3.5e-81 272.8 0.0 7.8e-81 271.6 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.15 EEQ32210.1 - 0.0027 16.1 0.3 0.0062 14.9 0.0 1.7 2 0 0 2 2 2 1 Adaptin N terminal region Arm PF00514.18 EEQ32210.1 - 0.0066 16.2 5.8 8.8 6.3 0.1 5.5 5 1 1 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EEQ32210.1 - 0.019 14.9 0.9 0.83 9.9 0.1 3.6 4 0 0 4 4 4 0 HEAT repeat HAD PF12710.2 EEQ32211.1 - 1e-12 48.6 0.0 1.3e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEQ32211.1 - 0.0001 22.5 0.0 0.00043 20.5 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EEQ32211.1 - 0.00015 21.1 0.0 0.00066 19.0 0.0 1.9 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 EEQ32211.1 - 0.0016 17.6 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase BTB PF00651.26 EEQ32212.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RTA1 PF04479.8 EEQ32214.1 - 1e-14 54.5 10.6 4.5e-14 52.4 7.3 1.8 1 1 0 1 1 1 1 RTA1 like protein Pkinase PF00069.20 EEQ32215.1 - 3.1e-13 49.4 0.5 5.3e-06 25.7 0.0 2.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32215.1 - 0.0034 16.4 0.6 0.038 13.0 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.18 EEQ32215.1 - 0.0043 16.8 0.1 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family tRNA-synt_1g PF09334.6 EEQ32216.1 - 5e-131 436.9 0.0 8e-131 436.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEQ32216.1 - 4e-06 25.1 0.2 0.0028 15.7 0.0 3.3 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEQ32216.1 - 0.00023 20.9 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA YgbA_NO PF11756.3 EEQ32216.1 - 0.016 15.2 0.4 0.029 14.3 0.2 1.4 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter DUF1703 PF08011.6 EEQ32217.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1703) MbeB_N PF04837.7 EEQ32217.1 - 0.091 12.8 0.2 0.52 10.4 0.7 1.7 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Sulfatase PF00884.18 EEQ32219.1 - 1.3e-65 221.5 0.0 9.6e-50 169.4 0.0 2.1 1 1 1 2 2 2 2 Sulfatase DUF229 PF02995.12 EEQ32219.1 - 0.00066 18.2 0.0 0.00092 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 EEQ32219.1 - 0.015 15.5 0.2 0.76 10.0 0.2 2.6 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.19 EEQ32220.1 - 2.6e-69 233.9 9.5 3e-69 233.7 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ32220.1 - 1.5e-13 50.2 22.4 3.2e-13 49.1 12.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EEQ32220.1 - 0.0052 16.7 3.6 0.088 12.8 0.5 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) Zn_clus PF00172.13 EEQ32221.1 - 7.4e-10 38.5 7.1 2e-09 37.1 4.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1150 PF06620.6 EEQ32222.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) Abhydrolase_3 PF07859.8 EEQ32224.1 - 7.9e-49 166.0 0.1 9.9e-49 165.7 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEQ32224.1 - 7.2e-11 41.4 0.2 2.2e-10 39.8 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family AATase PF07247.7 EEQ32225.1 - 7.9e-19 67.5 0.0 7.5e-18 64.3 0.0 2.1 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EEQ32225.1 - 0.0029 16.5 0.0 0.0052 15.6 0.0 1.4 1 0 0 1 1 1 1 Condensation domain APH PF01636.18 EEQ32226.1 - 4.3e-13 49.5 0.1 6.2e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ32226.1 - 0.0026 17.1 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Fungal_trans PF04082.13 EEQ32227.1 - 5.6e-11 41.8 0.6 9.2e-11 41.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EEQ32228.1 - 6.3e-32 110.6 83.8 1.3e-21 76.7 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ32228.1 - 1.1e-06 28.2 2.0 6e-05 22.7 1.6 2.9 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 EEQ32228.1 - 0.0013 17.4 49.6 0.014 14.0 7.3 3.1 1 1 2 3 3 3 2 Sugar (and other) transporter DUF1435 PF07256.7 EEQ32228.1 - 5 7.1 10.7 6 6.9 2.5 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1435) CRPA PF05745.6 EEQ32228.1 - 8.9 6.1 7.1 0.97 9.2 1.3 2.0 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) AMP-binding PF00501.23 EEQ32229.1 - 1.4e-75 254.2 0.1 2.7e-75 253.3 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEQ32229.1 - 2e-15 56.3 0.0 2.9e-11 42.7 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein PP-binding PF00550.20 EEQ32229.1 - 3.1e-09 36.9 0.0 1.2e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 EEQ32229.1 - 0.00021 20.8 0.0 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EEQ32229.1 - 0.0016 19.3 0.7 0.027 15.4 0.1 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.12 EEQ32229.1 - 0.025 13.4 0.0 0.053 12.4 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4637 PF15470.1 EEQ32230.1 - 1.4 8.5 7.2 2.8 7.5 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF763 PF05559.6 EEQ32230.1 - 2.8 6.7 6.5 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF763) APG6 PF04111.7 EEQ32230.1 - 4.6 6.1 13.7 7.9 5.4 9.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 FG-GAP PF01839.18 EEQ32232.1 - 1.4e-21 75.5 2.2 0.00043 19.8 0.1 4.8 4 0 0 4 4 4 4 FG-GAP repeat VCBS PF13517.1 EEQ32232.1 - 4.3e-20 71.8 13.7 1.3e-09 38.2 1.0 4.1 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 EEQ32232.1 - 1.6e-10 40.7 0.3 0.16 11.3 0.0 4.1 4 0 0 4 4 4 4 Insecticide toxin TcdB middle/N-terminal region DUF1918 PF08940.6 EEQ32232.1 - 0.0031 16.8 0.1 0.56 9.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1918) GHL13 PF14883.1 EEQ32232.1 - 0.026 13.7 1.3 0.28 10.3 0.0 2.8 4 0 0 4 4 4 0 Hypothetical glycosyl hydrolase family 13 Lipase_GDSL PF00657.17 EEQ32232.1 - 0.055 13.2 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase EF-hand_5 PF13202.1 EEQ32232.1 - 2.6 7.5 15.6 23 4.5 0.1 4.5 4 0 0 4 4 4 0 EF hand FAD_binding_3 PF01494.14 EEQ32233.1 - 4.7e-14 52.2 1.1 6.3e-05 22.1 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EEQ32233.1 - 0.0021 18.0 0.0 0.0056 16.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ32233.1 - 0.0023 16.9 0.1 0.0038 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ32233.1 - 0.028 13.2 0.0 0.063 12.1 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain EthD PF07110.6 EEQ32234.1 - 5.5e-22 78.5 0.1 6.7e-22 78.2 0.1 1.1 1 0 0 1 1 1 1 EthD domain ketoacyl-synt PF00109.21 EEQ32235.1 - 1.2e-75 254.3 0.0 2.8e-75 253.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ32235.1 - 3e-46 158.2 0.0 5e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEQ32235.1 - 6e-31 106.7 0.6 1.3e-30 105.6 0.2 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EEQ32235.1 - 4.7e-26 92.4 0.0 1.9e-25 90.4 0.0 2.1 2 0 0 2 2 1 1 Thioesterase domain PP-binding PF00550.20 EEQ32235.1 - 5.1e-21 74.7 2.4 3.2e-10 40.1 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EEQ32235.1 - 1.4e-14 53.9 0.0 2.6e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 EEQ32235.1 - 8.2e-08 32.3 1.3 3.1e-05 23.9 0.0 3.0 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ32235.1 - 2.4e-06 27.3 0.1 0.026 14.2 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EEQ32235.1 - 2.9e-05 23.1 0.0 9.5e-05 21.4 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF2974 PF11187.3 EEQ32235.1 - 0.015 14.6 0.0 0.05 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) TAFH PF07531.9 EEQ32235.1 - 0.075 12.6 0.0 4.7 6.9 0.0 2.5 2 0 0 2 2 2 0 NHR1 homology to TAF Vps16_C PF04840.7 EEQ32235.1 - 0.71 8.7 0.0 1.3 7.9 0.0 1.3 1 0 0 1 1 1 0 Vps16, C-terminal region MFS_1 PF07690.11 EEQ32236.1 - 9.7e-40 136.3 36.4 1.5e-39 135.7 25.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Imm_superinfect PF14373.1 EEQ32236.1 - 0.069 12.7 5.2 0.29 10.7 1.4 2.7 2 0 0 2 2 2 0 Superinfection immunity protein Nitroreductase PF00881.19 EEQ32237.1 - 2.1e-11 43.9 0.0 2.4e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family AflR PF08493.5 EEQ32238.1 - 0.0095 15.0 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Aflatoxin regulatory protein Thioesterase PF00975.15 EEQ32239.1 - 8.8e-23 81.7 0.0 7.8e-21 75.3 0.0 2.1 1 1 1 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.2 EEQ32239.1 - 9.6e-07 28.9 0.0 6.7e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EEQ32239.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EEQ32239.1 - 0.042 13.6 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ32239.1 - 0.049 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Beta-lactamase PF00144.19 EEQ32240.1 - 3.4e-19 69.0 0.1 3.2e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase PTase_Orf2 PF11468.3 EEQ32241.1 - 5.9e-69 232.5 0.0 7.2e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Aromatic prenyltransferase Orf2 Cu-oxidase_3 PF07732.10 EEQ32242.1 - 1.5e-19 69.8 0.1 2.5e-19 69.1 0.0 1.3 1 1 0 1 1 1 1 Multicopper oxidase Kinesin PF00225.18 EEQ32243.1 - 1.1e-89 300.4 0.0 1.1e-89 300.4 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Bacillus_HBL PF05791.6 EEQ32243.1 - 0.0071 15.7 2.8 0.04 13.2 0.0 2.4 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF1460 PF07313.7 EEQ32243.1 - 0.42 9.7 6.6 0.036 13.2 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) V_ATPase_I PF01496.14 EEQ32243.1 - 1.2 6.8 7.1 2.1 6.1 4.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IF-2B PF01008.12 EEQ32244.1 - 7.3e-71 238.4 0.1 9.4e-71 238.0 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family TFIIA PF03153.8 EEQ32244.1 - 4.9 6.9 12.5 9.7 5.9 8.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apc13p PF05839.6 EEQ32245.1 - 8.8e-19 67.2 0.8 2.3e-15 56.3 0.0 2.2 1 1 0 2 2 2 2 Apc13p protein Pol_alpha_B_N PF08418.5 EEQ32246.1 - 6.1e-61 206.1 0.0 7.8e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EEQ32246.1 - 2.1e-33 115.3 0.0 2.9e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.15 EEQ32247.1 - 7.4e-35 119.7 0.0 1.1e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEQ32247.1 - 5.4e-12 45.6 0.1 1.8e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEQ32247.1 - 0.00076 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HrpB_C PF08482.5 EEQ32247.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal CBS PF00571.23 EEQ32248.1 - 8.2e-20 70.3 6.5 3.3e-10 39.5 0.3 4.1 4 0 0 4 4 4 3 CBS domain RhoGAP PF00620.22 EEQ32249.1 - 0.043 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain Jiraiya PF15038.1 EEQ32249.1 - 0.11 11.8 0.3 1.2 8.5 0.1 2.1 2 0 0 2 2 2 0 Jiraiya WASH-7_C PF14746.1 EEQ32250.1 - 0.088 12.4 1.0 0.12 11.9 0.7 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal PAT1 PF09770.4 EEQ32250.1 - 0.16 10.1 11.4 0.18 10.0 7.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2721 PF11026.3 EEQ32250.1 - 3.6 7.2 6.1 5.5 6.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) bZIP_Maf PF03131.12 EEQ32250.1 - 7.1 6.9 17.6 15 5.9 11.4 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor ECH_C PF13766.1 EEQ32251.1 - 4.1e-38 130.1 0.1 1.1e-37 128.8 0.0 1.7 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EEQ32251.1 - 5.4e-27 94.4 0.0 1.6e-26 92.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ELF PF03317.8 EEQ32251.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 ELF protein Ribosomal_L4 PF00573.17 EEQ32252.1 - 1.8e-45 154.7 0.0 3.1e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 EEQ32253.1 - 6.1e-10 39.1 0.0 9.3e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran_2 PF12848.2 EEQ32253.1 - 0.62 9.9 6.3 1.3 8.9 4.4 1.5 1 0 0 1 1 1 0 ABC transporter Peptidase_S24 PF00717.18 EEQ32254.1 - 1.5e-08 34.1 0.0 2.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EEQ32254.1 - 0.00044 19.7 0.0 0.0041 16.6 0.0 2.1 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Lactamase_B PF00753.22 EEQ32255.1 - 1.9e-28 99.4 5.9 2.5e-28 99.0 4.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEQ32255.1 - 4.1e-07 29.7 0.6 5.9e-07 29.2 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EEQ32255.1 - 0.033 13.4 0.0 0.07 12.4 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Las1 PF04031.8 EEQ32256.1 - 2e-46 157.4 0.1 3.3e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Las1-like NAD_kinase PF01513.16 EEQ32259.1 - 2.9e-71 239.5 0.0 3.6e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase TRAPP PF04051.11 EEQ32260.1 - 3.1e-35 120.9 0.0 4.1e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Prp19_bind PF06991.6 EEQ32261.1 - 5.6e-45 153.7 23.0 5.6e-45 153.7 16.0 2.2 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain Glyco_hydro_16 PF00722.16 EEQ32262.1 - 1.6e-43 148.1 1.8 2.7e-43 147.4 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Rep_fac-A_3 PF08661.6 EEQ32263.1 - 1.5e-17 63.5 0.0 1.7e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA_anti-codon PF01336.20 EEQ32263.1 - 0.089 12.6 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain GATA PF00320.22 EEQ32264.1 - 3.7e-05 22.9 5.9 0.00087 18.5 0.8 2.5 2 0 0 2 2 2 2 GATA zinc finger LSM PF01423.17 EEQ32265.1 - 7.7e-19 67.0 0.1 1.1e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain CAV_VP3 PF04771.7 EEQ32265.1 - 0.029 14.3 0.1 4.7 7.2 0.0 2.0 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein Dak1 PF02733.12 EEQ32266.1 - 1.1e-113 379.0 1.4 1.6e-113 378.6 0.9 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EEQ32266.1 - 1.1e-48 165.2 0.1 9.3e-48 162.1 0.1 2.3 2 0 0 2 2 2 1 DAK2 domain Cullin PF00888.17 EEQ32267.1 - 3e-123 412.4 3.3 3.7e-123 412.1 2.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEQ32267.1 - 4e-25 87.4 2.1 9.9e-25 86.1 1.4 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 EEQ32267.1 - 0.00043 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 HbrB-like DUF3414 PF11894.3 EEQ32268.1 - 0 1294.7 26.9 0 1140.7 10.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 EEQ32269.1 - 2.8e-45 154.6 0.2 5.9e-45 153.5 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EEQ32269.1 - 3e-41 140.7 0.2 9.9e-41 139.0 0.1 2.0 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EEQ32269.1 - 1.2e-07 31.0 0.3 3e-07 29.7 0.2 1.7 1 0 0 1 1 1 1 FATC domain DUF1353 PF07087.6 EEQ32269.1 - 0.026 14.0 0.1 0.67 9.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) UPF0052 PF01933.13 EEQ32270.1 - 1.8e-50 171.9 0.0 2.5e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Rad50_zn_hook PF04423.9 EEQ32271.1 - 0.0073 15.7 0.4 0.8 9.2 0.0 2.5 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 EEQ32271.1 - 0.052 13.4 1.8 0.48 10.3 1.5 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EEQ32271.1 - 0.084 12.7 4.7 0.66 9.8 3.3 2.1 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ32271.1 - 0.12 12.0 5.5 1.1 8.9 3.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 EEQ32271.1 - 0.14 12.2 0.5 17 5.6 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_2 PF13923.1 EEQ32271.1 - 0.33 11.0 2.3 2.9 7.9 1.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EEQ32271.1 - 0.52 10.0 2.3 9 6.1 0.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DNA_pol_A PF00476.15 EEQ32272.1 - 5.9e-100 334.5 0.0 8.1e-100 334.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EEQ32272.1 - 0.005 16.3 0.1 0.2 11.1 0.0 2.4 1 1 0 1 1 1 1 3'-5' exonuclease Mad3_BUB1_I PF08311.7 EEQ32272.1 - 0.072 12.8 0.2 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 CorA PF01544.13 EEQ32273.1 - 4.4e-24 85.0 2.5 1.1e-14 54.2 0.2 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Brr6_like_C_C PF10104.4 EEQ32273.1 - 0.16 11.4 0.2 0.33 10.4 0.1 1.5 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain SQS_PSY PF00494.14 EEQ32274.1 - 1.3e-45 155.8 0.0 2.2e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Soyouz_module PF14313.1 EEQ32274.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) SNF2_N PF00176.18 EEQ32275.1 - 2.8e-70 236.4 0.0 3.9e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EEQ32275.1 - 8.8e-23 80.2 0.0 1.7e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EEQ32275.1 - 4.4e-13 48.8 0.0 1.1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EEQ32275.1 - 2.9e-06 27.1 13.2 5.8e-06 26.2 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ32275.1 - 8.7e-05 22.1 9.9 0.00016 21.3 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ32275.1 - 0.0012 18.6 11.5 0.0027 17.4 7.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ32275.1 - 0.0027 17.3 13.5 0.0057 16.2 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ32275.1 - 0.015 14.9 11.7 0.031 13.9 8.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEQ32275.1 - 0.27 11.1 12.5 0.55 10.1 8.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ32275.1 - 1.3 8.7 9.3 3.3 7.5 6.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Lyase_1 PF00206.15 EEQ32276.1 - 1.2e-21 77.2 0.1 2e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EEQ32276.1 - 2.2e-15 56.4 0.0 6.5e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus GTP_EFTU PF00009.22 EEQ32278.1 - 8.7e-23 80.7 0.1 3.3e-22 78.8 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEQ32278.1 - 9.3e-16 57.8 0.0 2e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEQ32278.1 - 1.8e-06 27.9 1.0 1.8e-06 27.9 0.7 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EEQ32278.1 - 0.00036 20.0 0.4 0.8 9.1 0.1 3.5 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EEQ32278.1 - 0.0017 18.8 0.3 0.013 16.0 0.2 2.5 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ32278.1 - 0.0028 17.5 0.0 0.0072 16.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEQ32278.1 - 0.053 13.3 1.3 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 EEQ32278.1 - 0.067 12.9 0.2 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EEQ32278.1 - 0.082 12.3 0.2 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain LSM PF01423.17 EEQ32279.1 - 3.5e-13 48.8 0.4 5.6e-13 48.2 0.3 1.3 1 1 0 1 1 1 1 LSM domain ATP13 PF12921.2 EEQ32280.1 - 1.1e-28 99.1 0.0 2.4e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EEQ32280.1 - 2.8e-05 23.9 0.1 0.04 13.9 0.1 3.1 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 EEQ32280.1 - 6.3e-05 22.9 0.1 0.0017 18.4 0.0 3.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 EEQ32280.1 - 0.052 13.5 0.2 5.3 7.2 0.0 3.4 3 0 0 3 3 3 0 PPR repeat PIG-L PF02585.12 EEQ32281.1 - 1.5e-26 93.3 0.0 2.6e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Pkinase_Tyr PF07714.12 EEQ32282.1 - 9.9e-11 41.1 0.0 1.7e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EEQ32282.1 - 1.9e-09 37.0 0.0 1.4e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ32282.1 - 0.025 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ32282.1 - 0.039 13.5 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EEQ32282.1 - 0.074 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.26 EEQ32284.1 - 4.3e-19 68.0 0.5 1.2e-18 66.5 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EEQ32284.1 - 0.0054 16.3 0.2 0.02 14.4 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1843 PF08898.5 EEQ32284.1 - 0.36 10.9 3.9 0.75 9.8 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DDE_Tnp_ISL3 PF01610.12 EEQ32284.1 - 8.9 5.8 7.5 0.59 9.6 0.1 2.3 3 0 0 3 3 3 0 Transposase Mei4 PF13971.1 EEQ32285.1 - 7.6e-06 25.1 0.0 2.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 GCV_T PF01571.16 EEQ32286.1 - 1.9e-14 53.5 0.0 6.1e-14 51.8 0.0 1.8 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EEQ32286.1 - 7.2e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DCP2 PF05026.8 EEQ32287.1 - 8.1e-37 124.9 1.7 1.5e-36 124.1 1.1 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EEQ32287.1 - 6.1e-15 55.0 0.0 1.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain LysM PF01476.15 EEQ32288.1 - 4.6e-05 23.2 0.0 8.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 LysM domain Mucin PF01456.12 EEQ32288.1 - 0.15 11.7 36.4 0.025 14.3 22.4 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Med3 PF11593.3 EEQ32288.1 - 7.2 5.7 19.7 8.4 5.5 13.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4112 PF13430.1 EEQ32289.1 - 1.1e-34 118.5 0.2 1.5e-34 118.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2392 PF10288.4 EEQ32290.1 - 3.6e-24 85.1 0.0 5.8e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Lung_7-TM_R PF06814.8 EEQ32291.1 - 3.9e-73 245.9 19.7 4.8e-73 245.6 13.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4131 PF13567.1 EEQ32291.1 - 2.6 7.4 13.0 2 7.7 1.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1308 PF07000.6 EEQ32292.1 - 2.8e-77 259.7 0.0 4.9e-77 259.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) WD40 PF00400.27 EEQ32293.1 - 1.6e-11 43.6 7.3 1e-07 31.5 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat MRG PF05712.8 EEQ32293.1 - 0.038 12.8 0.2 0.066 12.0 0.1 1.3 1 1 0 1 1 1 0 MRG DUF4263 PF14082.1 EEQ32293.1 - 0.059 13.3 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) Mito_carr PF00153.22 EEQ32294.1 - 7.5e-57 189.0 4.2 1.9e-18 65.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_red_sm PF00268.16 EEQ32296.1 - 3.2e-116 387.2 0.8 3.8e-116 387.0 0.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain WD40 PF00400.27 EEQ32297.1 - 4.7e-30 102.3 4.6 7.9e-06 25.5 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat SRP9-21 PF05486.7 EEQ32297.1 - 2.6e-28 97.5 1.6 6.4e-28 96.3 1.1 1.7 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Nup160 PF11715.3 EEQ32297.1 - 0.045 11.8 1.2 2.8 5.9 0.4 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EEQ32297.1 - 0.16 11.7 0.0 15 5.3 0.0 3.7 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EEQ32297.1 - 0.2 12.0 1.0 6.5 7.1 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain APH PF01636.18 EEQ32298.1 - 1.5e-12 47.8 1.0 1.9e-11 44.1 0.1 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ32298.1 - 0.015 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase OHCU_decarbox PF09349.5 EEQ32299.1 - 6.2e-36 124.1 0.0 7.5e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase TruB_N PF01509.13 EEQ32301.1 - 2e-44 151.3 0.0 9.2e-44 149.1 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Hid1 PF12722.2 EEQ32301.1 - 0.37 8.4 2.9 0.48 8.0 2.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Drc1-Sld2 PF11719.3 EEQ32302.1 - 0.0008 18.6 7.0 0.0012 18.0 4.9 1.3 1 0 0 1 1 1 1 DNA replication and checkpoint protein Myc_N PF01056.13 EEQ32302.1 - 0.022 13.9 9.2 0.069 12.3 6.4 1.8 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 EEQ32302.1 - 0.11 10.4 6.0 0.17 9.7 4.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNMT1-RFD PF12047.3 EEQ32302.1 - 0.27 10.9 3.9 0.35 10.5 0.0 2.9 4 0 0 4 4 4 0 Cytosine specific DNA methyltransferase replication foci domain PGA2 PF07543.7 EEQ32302.1 - 0.4 10.4 12.5 1.1 9.0 8.6 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 IBR PF01485.16 EEQ32302.1 - 0.89 9.4 4.3 9.3 6.2 0.1 2.9 2 1 0 2 2 2 0 IBR domain YqfQ PF14181.1 EEQ32302.1 - 2.7 7.9 9.6 6.3 6.8 6.7 1.6 1 0 0 1 1 1 0 YqfQ-like protein LLC1 PF14945.1 EEQ32302.1 - 7.3 6.9 9.4 0.83 9.9 0.3 2.6 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein CDC45 PF02724.9 EEQ32302.1 - 9.2 4.1 17.2 4.1 5.3 10.6 1.4 1 1 0 1 1 1 0 CDC45-like protein Ebp2 PF05890.7 EEQ32303.1 - 1e-89 300.4 16.0 1e-89 300.4 11.1 2.4 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 Thioredoxin PF00085.15 EEQ32304.1 - 2.3e-58 194.2 0.0 5.6e-29 99.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EEQ32304.1 - 3.2e-23 82.1 1.2 5.6e-23 81.3 0.3 1.8 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EEQ32304.1 - 2.4e-14 53.4 0.1 9.4e-06 25.8 0.0 3.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EEQ32304.1 - 9e-12 44.8 0.0 3.7e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EEQ32304.1 - 7e-10 38.8 0.0 0.0029 17.6 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EEQ32304.1 - 2.2e-05 24.1 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.1 EEQ32304.1 - 7.4e-05 22.6 0.1 0.066 13.0 0.0 2.7 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EEQ32304.1 - 0.00015 21.3 0.0 0.12 11.9 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Redoxin PF08534.5 EEQ32304.1 - 0.0044 16.5 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 EEQ32304.1 - 0.0049 16.8 1.6 8.5 6.3 0.1 3.7 3 2 0 3 3 3 2 Thioredoxin Glutaredoxin PF00462.19 EEQ32304.1 - 0.046 13.7 0.1 11 6.1 0.1 2.9 2 1 0 2 2 2 0 Glutaredoxin MKT1_C PF12246.3 EEQ32305.1 - 7.9e-78 260.7 0.0 1.1e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EEQ32305.1 - 3.2e-30 104.3 0.1 8.1e-30 102.9 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EEQ32305.1 - 3.1e-13 49.5 0.0 5.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EEQ32305.1 - 0.046 13.9 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 XPG N-terminal domain 2OG-FeII_Oxy PF03171.15 EEQ32306.1 - 3.4e-14 52.9 0.0 1.1e-13 51.2 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EEQ32306.1 - 5e-11 43.1 0.1 7.5e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WD40 PF00400.27 EEQ32308.1 - 6.5e-45 149.4 20.3 1.5e-09 37.3 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat CFEM PF05730.6 EEQ32309.1 - 4.1e-12 45.7 12.3 8.2e-12 44.7 8.5 1.5 1 0 0 1 1 1 1 CFEM domain Phosducin PF02114.11 EEQ32311.1 - 3.6e-10 39.0 0.0 8.6e-08 31.2 0.0 2.7 2 1 0 2 2 2 2 Phosducin Sox_N PF12444.3 EEQ32311.1 - 0.45 11.6 5.3 0.89 10.7 0.1 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal Pox_RNA_Pol_19 PF05320.7 EEQ32311.1 - 1.3 8.7 6.4 14 5.4 0.9 2.8 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit YEATS PF03366.11 EEQ32312.1 - 1.9e-20 72.3 0.0 3.3e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 YEATS family Ran_BP1 PF00638.13 EEQ32313.1 - 1.3e-35 122.0 8.2 1.3e-35 122.0 5.7 2.4 2 1 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 EEQ32313.1 - 0.016 14.9 0.3 0.077 12.7 0.2 1.9 1 1 0 1 1 1 0 WH1 domain CDC27 PF09507.5 EEQ32313.1 - 0.28 10.3 23.4 0.35 10.0 16.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Glyco_transf_15 PF01793.11 EEQ32316.1 - 1.9e-132 441.2 5.8 2.4e-132 440.8 4.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Peptidase_S58 PF03576.9 EEQ32317.1 - 1.3e-106 356.5 1.7 1.5e-106 356.3 1.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 APH PF01636.18 EEQ32320.1 - 1.1e-08 35.1 0.0 3.1e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 EEQ32320.1 - 0.00083 19.1 6.5 0.0016 18.2 4.5 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Imm10 PF15562.1 EEQ32320.1 - 0.14 11.9 0.2 0.3 10.8 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 10 PH PF00169.24 EEQ32321.1 - 3.5e-27 94.6 1.5 1.4e-14 54.1 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 EEQ32321.1 - 6.3e-13 48.9 4.2 9e-08 32.2 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EEQ32321.1 - 1.1e-10 41.7 5.8 4.9e-05 23.5 0.1 4.0 3 2 0 3 3 3 2 Pleckstrin homology domain PH_6 PF15406.1 EEQ32321.1 - 6.7e-05 22.9 0.1 0.0058 16.6 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain UIM PF02809.15 EEQ32321.1 - 0.025 14.0 1.0 0.062 12.9 0.7 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DOT1 PF08123.8 EEQ32322.1 - 2e-75 252.6 0.0 3.1e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EEQ32322.1 - 2.6e-07 30.6 0.1 2e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ32322.1 - 0.00072 20.1 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ32322.1 - 0.00076 19.0 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 EEQ32322.1 - 0.016 15.2 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 EEQ32322.1 - 0.019 14.2 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family ATG16 PF08614.6 EEQ32323.1 - 8.1e-40 136.7 14.2 9.7e-40 136.4 9.8 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TTKRSYEDQ PF10212.4 EEQ32323.1 - 0.0061 15.5 3.4 0.0071 15.3 2.4 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DUF4591 PF15261.1 EEQ32323.1 - 0.013 15.7 1.7 0.013 15.7 1.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4591) DUF4463 PF14703.1 EEQ32323.1 - 0.018 15.5 2.1 0.1 13.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) GvpG PF05120.7 EEQ32323.1 - 0.035 13.9 0.5 0.035 13.9 0.4 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Cep57_MT_bd PF06657.8 EEQ32323.1 - 0.045 13.7 4.3 4.3 7.3 0.2 2.7 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SecD-TM1 PF13721.1 EEQ32323.1 - 0.35 11.1 1.9 0.66 10.2 0.9 1.8 1 1 0 1 1 1 0 SecD export protein N-terminal TM region Ras PF00071.17 EEQ32324.1 - 6.9e-56 188.0 0.2 8.3e-56 187.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ32324.1 - 3.9e-20 72.5 0.0 7e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ32324.1 - 9e-14 51.0 0.0 1.1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ32324.1 - 4.5e-08 32.5 0.0 5.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEQ32324.1 - 9.5e-08 31.6 0.0 2.1e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ32324.1 - 2.8e-07 30.5 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEQ32324.1 - 0.00037 20.6 0.0 0.00066 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEQ32324.1 - 0.00082 18.5 0.1 0.0017 17.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EEQ32324.1 - 0.003 17.0 0.0 0.07 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EEQ32324.1 - 0.0034 17.1 0.5 0.0098 15.6 0.1 1.8 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EEQ32324.1 - 0.005 16.2 0.0 0.024 14.0 0.0 1.8 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EEQ32324.1 - 0.0054 16.4 0.1 0.015 14.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EEQ32324.1 - 0.006 16.1 0.2 0.01 15.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EEQ32324.1 - 0.0061 16.2 0.0 0.0096 15.6 0.0 1.3 1 0 0 1 1 1 1 NTPase Septin PF00735.13 EEQ32324.1 - 0.0082 15.1 0.2 0.032 13.2 0.0 2.0 3 0 0 3 3 3 1 Septin ATP_bind_1 PF03029.12 EEQ32324.1 - 0.0088 15.6 0.2 0.27 10.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EEQ32324.1 - 0.0095 15.1 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EEQ32324.1 - 0.011 15.2 0.2 0.027 13.9 0.1 1.6 1 1 1 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EEQ32324.1 - 0.014 15.4 0.0 0.051 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EEQ32324.1 - 0.015 15.0 0.1 0.033 13.8 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EEQ32324.1 - 0.075 12.9 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEQ32324.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EEQ32324.1 - 0.15 12.3 0.1 0.33 11.2 0.0 1.6 2 0 0 2 2 2 0 ABC transporter TPT PF03151.11 EEQ32325.1 - 0.0019 17.8 11.0 0.0019 17.8 7.6 2.9 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 EEQ32325.1 - 0.0089 16.0 28.7 0.11 12.5 0.7 3.0 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EEQ32325.1 - 0.11 11.3 9.0 0.043 12.6 3.9 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) Spb1_C PF07780.7 EEQ32326.1 - 6.2e-75 251.3 23.3 6.2e-75 251.3 16.1 3.1 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EEQ32326.1 - 8.9e-56 187.7 9.8 8.9e-56 187.7 6.8 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EEQ32326.1 - 3.4e-53 180.2 0.0 7.2e-53 179.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Zn_clus PF00172.13 EEQ32328.1 - 3.4e-07 30.0 10.5 6.7e-07 29.1 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ32328.1 - 0.0022 16.8 0.0 0.0048 15.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_4 PF12763.2 EEQ32329.1 - 0.0035 17.0 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF3632 PF12311.3 EEQ32330.1 - 2.2e-35 122.1 0.4 2.7e-35 121.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Pkinase PF00069.20 EEQ32331.1 - 3.1e-71 239.5 0.0 3.9e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32331.1 - 6.2e-33 113.9 0.0 8.4e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEQ32331.1 - 1.2e-08 35.3 2.6 4e-08 33.6 1.8 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEQ32331.1 - 0.0035 16.3 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Herpes_BLLF1 PF05109.8 EEQ32331.1 - 2.5 5.9 11.1 3.2 5.5 7.7 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DNA_ligase_A_M PF01068.16 EEQ32332.1 - 1.1e-47 162.0 0.1 6.3e-47 159.5 0.0 2.3 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEQ32332.1 - 4.8e-37 127.4 0.0 2.8e-36 124.9 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEQ32332.1 - 7.2e-17 61.5 0.0 2e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EEQ32332.1 - 1.7e-09 37.6 0.1 5.8e-06 26.3 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEQ32332.1 - 7e-06 25.8 0.1 0.038 13.8 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain mRNA_cap_enzyme PF01331.14 EEQ32332.1 - 0.012 15.2 0.0 0.56 9.8 0.0 3.0 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain DNA_ligase_IV PF11411.3 EEQ32332.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA ligase IV Fungal_trans PF04082.13 EEQ32333.1 - 1.2e-46 158.6 0.1 2.3e-46 157.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Metallophos PF00149.23 EEQ32334.1 - 7.6e-36 123.3 0.4 1.2e-28 99.9 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Peptidase_A21 PF03566.8 EEQ32335.1 - 0.095 10.7 0.1 0.097 10.7 0.0 1.0 1 0 0 1 1 1 0 Peptidase family A21 PsbM PF05151.7 EEQ32335.1 - 0.13 11.8 1.1 0.23 11.0 0.8 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) DUF4646 PF15496.1 EEQ32336.1 - 3e-07 30.5 0.0 4.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) ALG3 PF05208.8 EEQ32337.1 - 3.1e-125 418.2 21.7 3.7e-125 418.0 15.0 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 EEQ32337.1 - 0.0034 16.3 17.5 0.0068 15.3 12.1 1.5 1 1 0 1 1 1 1 EpsG family eIF-1a PF01176.14 EEQ32338.1 - 4.4e-18 64.4 0.0 7.5e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 SNN_linker PF09050.5 EEQ32338.1 - 0.048 13.2 0.8 0.12 11.9 0.6 1.6 1 0 0 1 1 1 0 Stannin unstructured linker Pkinase PF00069.20 EEQ32339.1 - 8.3e-63 211.9 0.0 1.7e-62 210.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32339.1 - 2e-35 122.1 0.0 3.6e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EEQ32339.1 - 3.3e-33 113.2 12.8 7.6e-19 67.2 3.3 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EEQ32339.1 - 1e-15 57.1 22.1 2.6e-11 43.0 6.2 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EEQ32339.1 - 2.6e-14 53.4 2.2 8.9e-14 51.7 1.5 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Prok-RING_1 PF14446.1 EEQ32339.1 - 0.00096 18.8 7.5 0.00096 18.8 5.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Kinase-like PF14531.1 EEQ32339.1 - 0.018 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C2 PF00168.25 EEQ32339.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 C2 domain Uds1 PF15456.1 EEQ32339.1 - 3.2 7.7 5.7 0.68 9.9 0.7 2.1 2 0 0 2 2 2 0 Up-regulated During Septation PAT1 PF09770.4 EEQ32339.1 - 6.2 4.9 29.1 14 3.7 20.2 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD_2 PF13831.1 EEQ32339.1 - 8.7 5.7 15.2 7 6.0 2.0 2.4 2 0 0 2 2 2 0 PHD-finger TFCD_C PF12612.3 EEQ32341.1 - 2.4e-44 151.1 0.7 2.5e-43 147.7 0.1 2.5 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.1 EEQ32341.1 - 7.5e-05 23.0 1.0 1.2 9.6 0.0 4.8 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EEQ32341.1 - 0.00013 21.7 0.0 2 8.7 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EEQ32341.1 - 0.00041 20.5 0.2 2 8.7 0.2 3.5 2 0 0 2 2 2 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EEQ32341.1 - 0.024 14.9 0.0 2.1 8.7 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region APH PF01636.18 EEQ32342.1 - 3.1e-11 43.4 0.0 2.2e-10 40.6 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ32342.1 - 0.043 12.4 0.0 0.51 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) RRM_1 PF00076.17 EEQ32343.1 - 1.2e-25 88.8 3.6 4.1e-12 45.5 0.2 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ32343.1 - 1.2e-15 57.2 1.2 1.9e-06 27.7 0.0 2.8 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ32343.1 - 2.2e-15 56.2 0.0 2.6e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.12 EEQ32344.1 - 6.8e-65 218.3 2.3 8.9e-65 217.9 1.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.1 EEQ32344.1 - 0.019 14.9 2.6 0.019 14.9 1.8 2.1 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Nup54 PF13874.1 EEQ32344.1 - 1.7 8.2 5.7 1.9 8.1 0.2 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Viral_P18 PF04521.8 EEQ32344.1 - 2 7.8 5.7 15 5.0 0.1 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Prefoldin PF02996.12 EEQ32344.1 - 2.8 7.6 6.8 1.9 8.1 0.0 3.2 2 1 1 3 3 3 0 Prefoldin subunit TPR_12 PF13424.1 EEQ32345.1 - 5.9e-12 45.3 0.3 1 9.3 0.0 7.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ32345.1 - 1.6e-11 43.7 9.8 2.9 8.7 0.0 10.4 11 2 2 13 13 12 2 Tetratricopeptide repeat Suf PF05843.9 EEQ32345.1 - 4.4e-09 36.4 12.0 0.0078 15.9 0.2 5.7 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EEQ32345.1 - 2.8e-08 33.9 0.0 0.38 11.1 0.0 6.2 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ32345.1 - 9e-07 28.4 2.5 5.9 6.6 0.0 7.0 7 1 1 8 8 8 1 TPR repeat TPR_2 PF07719.12 EEQ32345.1 - 3.9e-06 26.3 11.5 1.1 9.3 0.0 7.3 7 0 0 7 7 6 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EEQ32345.1 - 2.1e-05 24.3 9.6 3.3 7.5 0.1 7.0 6 2 0 6 6 6 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 EEQ32345.1 - 4.4e-05 22.9 5.9 1.9 8.4 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ32345.1 - 0.00027 20.8 2.9 0.33 11.2 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ32345.1 - 0.0011 18.5 0.0 2.9 7.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ32345.1 - 0.0045 16.6 5.4 11 6.1 0.0 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat HAT PF02184.11 EEQ32345.1 - 0.0052 16.4 3.1 1.7 8.4 0.1 5.4 5 0 0 5 5 4 1 HAT (Half-A-TPR) repeat RGS PF00615.14 EEQ32345.1 - 0.036 14.1 0.6 0.51 10.4 0.2 2.9 2 0 0 2 2 2 0 Regulator of G protein signaling domain NRDE-2 PF08424.5 EEQ32345.1 - 0.051 12.4 11.2 0.028 13.3 1.6 4.8 3 2 1 4 4 4 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.1 EEQ32345.1 - 0.33 11.4 6.3 42 4.9 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Sec7 PF01369.15 EEQ32346.1 - 4e-57 192.9 0.0 6.8e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EEQ32346.1 - 1.1e-21 77.0 0.0 1e-14 54.3 0.0 2.9 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RhoGEF PF00621.15 EEQ32349.1 - 3.7e-21 75.8 0.0 1.3e-20 74.0 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 EEQ32349.1 - 2.6e-05 23.7 0.0 5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) HAUS6_N PF14661.1 EEQ32349.1 - 1.1 8.5 6.1 8.4 5.6 3.5 2.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus ATP_bind_3 PF01171.15 EEQ32350.1 - 1.7e-40 138.4 0.0 7.1e-39 133.1 0.0 2.3 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 EEQ32350.1 - 0.13 11.1 0.0 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 NAD synthase DUF3337 PF11816.3 EEQ32351.1 - 7e-53 180.1 7.0 5.5e-47 160.7 0.2 3.5 3 1 1 4 4 4 3 Domain of unknown function (DUF3337) Mito_carr PF00153.22 EEQ32351.1 - 8e-45 150.4 1.6 1.1e-17 63.4 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EEQ32351.1 - 9.6e-29 98.2 15.3 5e-08 32.5 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Pkinase PF00069.20 EEQ32352.1 - 1.3e-57 194.9 0.0 2.6e-57 193.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32352.1 - 1.2e-20 73.7 0.0 1.9e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ32352.1 - 0.0051 15.8 0.0 0.0092 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ32352.1 - 0.006 16.3 0.9 0.0098 15.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 EEQ32353.1 - 1.5e-26 91.6 0.1 4e-26 90.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EEQ32353.1 - 8.9e-23 80.2 0.1 1.5e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 EEQ32354.1 - 1.2e-106 356.3 0.0 1.3e-87 293.8 0.0 2.1 1 1 1 2 2 2 2 Svf1-like Acetyltransf_1 PF00583.19 EEQ32356.1 - 1.7e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ32356.1 - 0.0024 18.0 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CoA_binding_3 PF13727.1 EEQ32356.1 - 0.025 14.4 0.3 0.036 13.8 0.2 1.3 1 0 0 1 1 1 0 CoA-binding domain DHC_N1 PF08385.7 EEQ32358.1 - 7.3e-182 605.7 7.9 7.3e-182 605.7 5.5 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EEQ32358.1 - 5.8e-123 410.3 2.3 5.8e-123 410.3 1.6 3.9 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EEQ32358.1 - 8.2e-104 348.0 0.0 2.3e-103 346.5 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EEQ32358.1 - 7.6e-77 257.9 0.0 1.9e-76 256.6 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EEQ32358.1 - 1e-43 148.8 0.1 3.2e-43 147.1 0.1 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 EEQ32358.1 - 1.1e-32 113.2 0.8 2e-32 112.3 0.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EEQ32358.1 - 1.8e-28 98.9 0.0 5.3e-11 42.4 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 EEQ32358.1 - 9.5e-26 90.3 1.9 2.1e-21 76.0 0.0 3.7 2 1 1 3 3 3 2 P-loop containing dynein motor region D4 AAA_7 PF12775.2 EEQ32358.1 - 1.5e-19 70.1 0.0 8.7e-19 67.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EEQ32358.1 - 9.4e-16 58.1 0.9 0.0091 16.1 0.0 6.8 6 0 0 6 6 5 4 AAA domain AAA PF00004.24 EEQ32358.1 - 2.7e-14 53.5 0.0 0.0004 20.5 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEQ32358.1 - 1e-10 41.6 0.2 0.095 12.5 0.0 5.3 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EEQ32358.1 - 2.6e-09 37.9 0.1 0.043 14.6 0.0 5.6 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EEQ32358.1 - 4.4e-09 36.7 0.1 0.065 13.5 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EEQ32358.1 - 5.5e-07 29.7 7.6 0.12 12.3 0.1 7.4 6 1 1 7 7 7 1 AAA ATPase domain T2SE PF00437.15 EEQ32358.1 - 9.7e-07 27.9 0.0 0.075 11.9 0.0 3.7 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_14 PF13173.1 EEQ32358.1 - 3.2e-06 27.0 0.0 0.21 11.5 0.0 5.2 5 0 0 5 5 5 1 AAA domain AAA_19 PF13245.1 EEQ32358.1 - 1.6e-05 24.5 0.2 0.87 9.3 0.0 4.8 4 0 0 4 4 4 1 Part of AAA domain AAA_29 PF13555.1 EEQ32358.1 - 2.5e-05 23.6 0.0 2 8.0 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EEQ32358.1 - 3.1e-05 23.2 0.7 0.49 9.5 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EEQ32358.1 - 4.2e-05 23.8 0.1 2.7 8.2 0.0 4.7 3 0 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.7 EEQ32358.1 - 0.00013 21.1 0.3 0.91 8.5 0.0 4.2 4 0 0 4 4 4 2 Zeta toxin FtsK_SpoIIIE PF01580.13 EEQ32358.1 - 0.0004 19.9 0.0 5.4 6.4 0.0 3.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EEQ32358.1 - 0.0016 17.8 0.4 0.31 10.4 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF258 PF03193.11 EEQ32358.1 - 0.0054 15.9 0.1 14 4.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEQ32358.1 - 0.0055 16.1 1.4 0.43 9.9 0.0 4.1 5 0 0 5 5 4 1 AAA domain 3-alpha PF03475.9 EEQ32358.1 - 0.0067 16.1 0.2 0.023 14.4 0.1 1.9 1 0 0 1 1 1 1 3-alpha domain RNA_helicase PF00910.17 EEQ32358.1 - 0.013 15.6 0.8 18 5.5 0.0 4.5 5 0 0 5 5 4 0 RNA helicase MobB PF03205.9 EEQ32358.1 - 0.054 13.1 0.5 12 5.6 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EEQ32358.1 - 0.13 11.6 0.4 7 6.1 0.1 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ribonuclease_3 PF00636.21 EEQ32359.1 - 1.5e-38 131.7 0.0 2.3e-18 66.7 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEQ32359.1 - 5.4e-22 78.1 0.0 5.6e-12 45.7 0.0 3.3 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EEQ32359.1 - 3.5e-20 71.5 0.1 1.2e-18 66.6 0.0 2.9 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.10 EEQ32359.1 - 2.2e-13 50.4 0.1 4.8e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ32359.1 - 5.1e-13 48.6 0.1 1.3e-12 47.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ32359.1 - 5.1e-11 42.3 0.0 1.4e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 EEQ32359.1 - 0.012 16.2 0.3 1.8 9.2 0.0 2.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif T2SE PF00437.15 EEQ32359.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 EEQ32359.1 - 0.032 13.2 0.0 0.079 11.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TAP42 PF04177.7 EEQ32360.1 - 2.7e-108 361.9 1.0 3.1e-108 361.7 0.7 1.0 1 0 0 1 1 1 1 TAP42-like family CDC37_C PF08564.5 EEQ32360.1 - 0.12 12.2 1.7 10 6.0 0.0 3.3 3 2 0 3 3 3 0 Cdc37 C terminal domain DUF725 PF05267.7 EEQ32360.1 - 0.12 12.2 0.5 0.23 11.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) PilJ PF13675.1 EEQ32360.1 - 0.14 12.4 3.6 3.9 7.8 0.6 2.7 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Lipase_GDSL_2 PF13472.1 EEQ32361.1 - 5.1e-07 29.9 0.0 4.4e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ32361.1 - 2e-06 27.7 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Porphobil_deam PF01379.15 EEQ32362.1 - 5.5e-77 257.5 0.0 7.1e-77 257.1 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EEQ32362.1 - 2.5e-18 65.9 0.3 4.6e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.8 EEQ32363.1 - 6.1e-69 231.4 0.2 1.2e-68 230.4 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EEQ32363.1 - 1.7e-24 86.4 0.0 1.6e-23 83.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EEQ32363.1 - 1e-23 84.1 0.2 1e-23 84.1 0.1 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 EEQ32363.1 - 1e-08 34.6 0.0 2.7e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EEQ32363.1 - 1e-07 31.7 0.0 2.7e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EEQ32363.1 - 4.1e-06 25.7 0.1 3.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_16 PF13191.1 EEQ32363.1 - 4.2e-06 26.8 0.4 1.8e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EEQ32363.1 - 1.2e-05 24.7 0.0 3.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 EEQ32363.1 - 1.4e-05 24.7 0.0 4.9e-05 22.9 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ32363.1 - 3.1e-05 24.7 0.0 0.00013 22.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ32363.1 - 0.00013 21.6 0.1 0.00039 20.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 EEQ32363.1 - 0.00024 21.0 0.0 0.00075 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EEQ32363.1 - 0.00037 19.6 0.1 0.0014 17.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EEQ32363.1 - 0.00043 20.4 0.0 0.0045 17.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EEQ32363.1 - 0.0008 19.3 0.0 0.0023 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ32363.1 - 0.0014 18.5 0.1 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ32363.1 - 0.0028 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EEQ32363.1 - 0.0043 16.4 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EEQ32363.1 - 0.015 14.9 0.1 0.044 13.4 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EEQ32363.1 - 0.015 15.6 0.1 0.055 13.7 0.1 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEQ32363.1 - 0.018 15.1 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EEQ32363.1 - 0.019 14.0 0.2 0.046 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EEQ32363.1 - 0.02 14.6 0.3 1.2 8.7 0.0 3.1 2 1 0 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 EEQ32363.1 - 0.024 14.2 0.2 0.06 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEQ32363.1 - 0.024 14.2 0.0 0.068 12.8 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 EEQ32363.1 - 0.029 13.7 0.5 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 EEQ32363.1 - 0.032 13.4 0.0 0.077 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 EEQ32363.1 - 0.037 14.3 0.1 0.037 14.3 0.0 2.9 1 1 1 2 2 2 0 AAA domain AAA_PrkA PF08298.6 EEQ32363.1 - 0.042 12.5 0.1 0.19 10.3 0.1 1.9 1 1 1 2 2 2 0 PrkA AAA domain MobB PF03205.9 EEQ32363.1 - 0.058 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EEQ32363.1 - 0.058 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.1 EEQ32363.1 - 0.099 12.1 3.6 0.11 12.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.1 EEQ32363.1 - 0.11 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEQ32363.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.7 1 1 1 2 2 2 0 ABC transporter Ribosomal_L23 PF00276.15 EEQ32364.1 - 4.2e-15 55.4 0.0 7.2e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.17 EEQ32365.1 - 2.3e-41 141.2 0.4 6.7e-29 100.5 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EEQ32365.1 - 1.8e-31 108.0 0.0 4.2e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EEQ32365.1 - 3.9e-06 26.7 0.0 0.011 15.4 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEQ32365.1 - 3.9e-05 22.8 0.0 0.00094 18.2 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Chs3p PF12271.3 EEQ32366.1 - 4.4e-139 462.4 13.8 5.1e-139 462.2 9.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Ribosomal_L18e PF00828.14 EEQ32367.1 - 2.3e-17 63.5 0.1 4.3e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 EEQ32369.1 - 2.1e-49 168.0 0.0 2.9e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32369.1 - 1.6e-28 99.4 0.0 1.3e-27 96.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.23 EEQ32370.1 - 8.3e-06 25.0 0.0 1.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ32370.1 - 0.00043 19.8 0.0 0.0031 17.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain RCC1_2 PF13540.1 EEQ32371.1 - 1.8e-12 46.4 1.0 4.7e-06 26.0 0.0 4.3 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EEQ32371.1 - 2.7e-07 30.1 0.1 5.5e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ32371.1 - 0.014 15.0 0.1 0.035 13.7 0.1 1.7 1 0 0 1 1 1 0 F-box domain RCC1 PF00415.13 EEQ32371.1 - 0.018 15.2 0.0 1.5 9.0 0.0 3.8 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat PQ-loop PF04193.9 EEQ32372.1 - 4.7e-37 125.3 17.6 1.1e-19 69.7 1.4 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EEQ32372.1 - 0.003 17.3 6.7 0.018 14.8 0.1 2.7 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange 7TM_GPCR_Srsx PF10320.4 EEQ32372.1 - 0.0082 15.3 1.2 0.015 14.4 0.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Aminotran_1_2 PF00155.16 EEQ32375.1 - 3.9e-42 144.4 0.0 1e-35 123.3 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II AMP-binding PF00501.23 EEQ32376.1 - 1.4e-38 132.3 0.0 2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ32376.1 - 0.00037 21.4 0.0 0.0009 20.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M16_C PF05193.16 EEQ32377.1 - 2e-46 157.9 0.0 5.8e-45 153.2 0.0 2.5 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEQ32377.1 - 2.6e-40 137.5 0.0 3.5e-39 133.9 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Abhydrolase_2 PF02230.11 EEQ32378.1 - 5.2e-26 91.4 0.0 3e-17 62.7 0.0 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEQ32378.1 - 1.7e-07 31.3 0.4 4.5e-07 29.9 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ32378.1 - 4.8e-07 29.6 0.0 1e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ32378.1 - 0.00087 18.5 0.0 0.0023 17.2 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 EEQ32378.1 - 0.0067 15.8 0.0 0.016 14.6 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Tom22 PF04281.8 EEQ32379.1 - 6.2e-54 181.2 0.7 7.2e-54 181.0 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Rsbr_N PF08678.5 EEQ32379.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Rsbr N terminal DUF4211 PF13926.1 EEQ32380.1 - 1.7e-37 128.1 0.0 3.3e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DUF4449 PF14613.1 EEQ32381.1 - 4.5e-67 225.0 1.5 4.5e-67 225.0 1.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Ribosomal_L36e PF01158.13 EEQ32381.1 - 0.35 10.8 5.4 0.092 12.7 0.7 2.4 2 0 0 2 2 2 0 Ribosomal protein L36e Peptidase_M35 PF02102.10 EEQ32382.1 - 8.2e-94 314.1 7.0 1e-93 313.8 4.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EEQ32382.1 - 4.7e-08 33.6 0.1 8.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EEQ32382.1 - 0.00013 21.4 0.4 0.00029 20.3 0.3 1.6 1 1 0 1 1 1 1 Putative peptidase family Lipoprotein_9 PF03180.9 EEQ32382.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 NLPA lipoprotein vWA-TerF-like PF10138.4 EEQ32385.1 - 1.2e-07 31.7 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EEQ32385.1 - 0.012 15.7 0.1 0.037 14.1 0.1 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain E1-E2_ATPase PF00122.15 EEQ32386.1 - 1.6e-20 73.1 1.5 6.1e-20 71.2 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ32386.1 - 1.6e-17 64.6 0.0 8.4e-16 59.0 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ32386.1 - 1.1e-14 55.0 0.0 7.2e-14 52.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ32386.1 - 4.5e-12 45.7 0.0 3e-11 43.1 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ32386.1 - 0.0018 17.8 0.1 0.0055 16.3 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Homeobox PF00046.24 EEQ32387.1 - 3.3e-20 71.4 3.3 7.4e-20 70.3 2.3 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EEQ32387.1 - 0.00017 21.1 0.4 0.00055 19.5 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain PGP_phosphatase PF09419.5 EEQ32388.1 - 7.1e-48 162.1 0.0 8.4e-48 161.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EEQ32388.1 - 7.8e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEQ32388.1 - 0.016 15.5 0.2 4.7 7.5 0.2 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase LSM PF01423.17 EEQ32389.1 - 1.8e-13 49.8 0.3 2.3e-13 49.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain Adaptin_binding PF10199.4 EEQ32390.1 - 2.8e-16 60.0 1.6 2.8e-16 60.0 1.1 1.8 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 PTPLA PF04387.9 EEQ32391.1 - 3.9e-26 91.4 0.1 1.2e-25 89.8 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SRP72 PF08492.7 EEQ32392.1 - 2.1e-11 44.0 2.6 2.1e-11 44.0 1.8 2.0 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 EEQ32392.1 - 3.3e-08 33.7 0.2 0.67 10.3 0.1 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ32392.1 - 0.00023 20.8 8.5 0.25 11.3 0.3 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ32392.1 - 0.002 18.1 4.9 9 6.5 0.0 4.7 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EEQ32392.1 - 0.038 14.1 0.1 13 5.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ32392.1 - 0.057 13.8 0.0 76 4.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ32392.1 - 0.066 13.1 2.8 0.89 9.5 0.5 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ32392.1 - 0.15 12.7 1.0 1.2e+02 3.4 0.1 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Homeobox_KN PF05920.6 EEQ32393.1 - 4.4e-19 67.9 1.1 1.2e-18 66.5 0.7 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EEQ32393.1 - 0.00016 21.1 0.2 0.0003 20.3 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain gerPA PF10676.4 EEQ32394.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF FAD_binding_1 PF00667.15 EEQ32396.1 - 1.1e-39 136.0 0.0 1.7e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEQ32396.1 - 1.5e-09 38.3 0.0 4e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain ABC_membrane PF00664.18 EEQ32397.1 - 3.2e-80 269.5 37.0 1.2e-43 149.4 7.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ32397.1 - 1.8e-53 180.5 0.0 2.9e-33 115.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ32397.1 - 1.1e-11 44.4 1.2 1.5e-05 24.3 0.0 3.7 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ32397.1 - 4.1e-10 40.0 0.0 0.00074 19.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ32397.1 - 2e-08 34.4 3.9 0.0013 18.7 0.0 3.5 3 1 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 EEQ32397.1 - 1.4e-07 30.9 0.3 0.0099 15.3 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ32397.1 - 3.7e-07 30.9 0.1 0.013 16.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EEQ32397.1 - 2.2e-06 26.9 0.0 0.024 13.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEQ32397.1 - 6.4e-06 26.3 0.2 0.17 12.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EEQ32397.1 - 7.2e-06 25.7 0.1 1.4 8.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EEQ32397.1 - 1.9e-05 25.0 0.3 0.064 13.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EEQ32397.1 - 7.3e-05 22.9 0.1 2.3 8.4 0.1 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EEQ32397.1 - 7.7e-05 22.1 0.3 0.12 11.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EEQ32397.1 - 0.00024 21.0 0.0 0.41 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EEQ32397.1 - 0.0011 17.6 0.1 0.0045 15.6 0.1 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.1 EEQ32397.1 - 0.0014 18.9 0.0 0.65 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EEQ32397.1 - 0.0028 17.4 0.0 3 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEQ32397.1 - 0.0031 16.6 0.1 7.5 5.5 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin MobB PF03205.9 EEQ32397.1 - 0.0061 16.2 0.2 2.4 7.8 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EEQ32397.1 - 0.0075 15.7 2.4 1.8 7.8 0.1 3.2 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 EEQ32397.1 - 0.015 15.1 0.0 8.8 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.15 EEQ32397.1 - 0.019 14.5 0.0 3.7 7.1 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.12 EEQ32397.1 - 0.022 14.5 1.9 0.097 12.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 NB-ARC PF00931.17 EEQ32397.1 - 0.045 12.6 0.0 6.2 5.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 EEQ32397.1 - 0.05 12.2 0.1 0.1 11.2 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Dynamin_N PF00350.18 EEQ32397.1 - 0.085 12.6 0.1 92 2.7 0.0 3.9 4 0 0 4 4 4 0 Dynamin family RNA_helicase PF00910.17 EEQ32397.1 - 0.094 12.8 0.0 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 EEQ32397.1 - 0.095 12.6 0.5 9.2 6.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EEQ32397.1 - 0.1 12.5 0.3 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhyH PF05721.8 EEQ32398.1 - 8.6e-20 71.6 0.4 1.2e-19 71.2 0.3 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Med20 PF08612.6 EEQ32399.1 - 2.8e-59 199.9 0.0 3.6e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_8 PF13833.1 EEQ32400.1 - 3.9e-28 96.8 5.2 1.6e-11 43.6 0.2 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EEQ32400.1 - 8.1e-27 90.4 6.4 1.7e-09 36.2 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EEQ32400.1 - 3e-24 84.9 2.1 1.9e-15 56.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEQ32400.1 - 5.3e-17 60.1 3.9 5.5e-09 35.1 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EEQ32400.1 - 5e-16 57.2 4.8 3.4e-06 26.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EEQ32400.1 - 8e-09 35.2 0.2 0.00066 19.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 EEQ32400.1 - 2.8e-07 30.0 0.1 0.053 13.1 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 EEQ32400.1 - 0.00015 21.4 0.7 0.29 10.8 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EEQ32400.1 - 0.00029 20.7 0.1 0.0011 18.8 0.0 1.9 2 1 0 2 2 2 1 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.4 EEQ32400.1 - 0.0016 18.4 0.1 0.21 11.6 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region RNA_pol_Rpb4 PF03874.11 EEQ32400.1 - 0.0016 18.3 0.3 0.57 10.1 0.0 2.5 3 0 0 3 3 3 2 RNA polymerase Rpb4 Tenui_NCP PF04876.7 EEQ32400.1 - 0.06 12.8 0.0 0.099 12.1 0.0 1.5 1 1 0 1 1 1 0 Tenuivirus major non-capsid protein PB1 PF00564.19 EEQ32400.1 - 0.4 10.3 3.1 24 4.6 0.0 3.0 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 EEQ32401.1 - 1.5e-17 63.0 2.4 1.5e-17 63.0 1.7 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EEQ32401.1 - 1.2e-10 41.4 3.6 3.8e-10 39.8 0.2 2.3 2 0 0 2 2 2 1 Syntaxin DUF3357 PF11837.3 EEQ32401.1 - 0.0076 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) MCPsignal PF00015.16 EEQ32401.1 - 0.31 10.5 5.8 0.27 10.7 0.7 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CTD_bind PF04818.8 EEQ32402.1 - 8.5e-07 29.1 2.0 4.8e-06 26.7 0.1 2.5 1 1 1 2 2 2 1 RNA polymerase II-binding domain. DnaG_DnaB_bind PF08278.6 EEQ32402.1 - 0.92 9.7 5.2 0.69 10.1 0.2 2.5 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding MSP1_C PF07462.6 EEQ32402.1 - 1.9 6.7 4.6 0.3 9.4 0.0 1.8 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Clathrin_lg_ch PF01086.12 EEQ32403.1 - 3.2e-69 233.2 4.6 3.6e-69 233.1 3.2 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF4140 PF13600.1 EEQ32403.1 - 0.17 12.3 3.3 0.12 12.8 0.6 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Acyl_transf_3 PF01757.17 EEQ32404.1 - 1.1e-24 86.9 36.3 1.7e-24 86.3 25.2 1.3 1 1 0 1 1 1 1 Acyltransferase family Mannosyl_trans3 PF11051.3 EEQ32405.1 - 2.2e-69 233.8 0.0 8.8e-69 231.8 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative CDC37_N PF03234.9 EEQ32407.1 - 1.7e-60 204.3 4.7 1.7e-60 204.3 3.2 2.2 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EEQ32407.1 - 4.4e-43 146.7 0.0 1.1e-42 145.4 0.0 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EEQ32407.1 - 1.2e-25 89.1 0.5 1.2e-25 89.1 0.3 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain MecA_N PF05223.6 EEQ32407.1 - 0.0029 17.6 1.1 0.019 14.9 0.2 2.5 2 0 0 2 2 2 1 NTF2-like N-terminal transpeptidase domain DUF77 PF01910.12 EEQ32407.1 - 0.11 12.1 0.2 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF77 DUF3552 PF12072.3 EEQ32407.1 - 0.34 10.0 5.7 0.12 11.5 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF3287 PF11690.3 EEQ32407.1 - 0.68 10.0 3.8 11 6.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) ABC_membrane PF00664.18 EEQ32408.1 - 1.3e-45 155.9 12.5 1.7e-45 155.5 8.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ32408.1 - 3.1e-35 121.4 0.1 9.7e-35 119.8 0.0 1.9 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EEQ32408.1 - 4.1e-07 29.4 0.1 3.4e-05 23.1 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEQ32408.1 - 0.00024 21.1 0.2 0.00024 21.1 0.2 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 EEQ32408.1 - 0.00028 20.9 0.3 0.74 9.7 0.1 2.5 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEQ32408.1 - 0.00085 19.4 0.1 0.005 16.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEQ32408.1 - 0.0013 18.2 0.3 0.0036 16.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ32408.1 - 0.0047 17.7 0.0 0.011 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEQ32408.1 - 0.0093 15.3 0.5 0.11 11.9 0.4 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ32408.1 - 0.01 15.2 0.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 EEQ32408.1 - 0.012 15.1 1.2 0.073 12.4 0.2 2.2 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 EEQ32408.1 - 0.021 15.0 0.0 0.11 12.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEQ32408.1 - 0.027 14.7 0.2 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EEQ32408.1 - 0.038 12.5 0.7 0.12 10.9 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF258 PF03193.11 EEQ32408.1 - 0.072 12.2 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EEQ32408.1 - 0.092 12.4 0.1 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EEQ32408.1 - 0.14 12.0 2.8 0.36 10.7 0.3 2.9 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EEQ32408.1 - 0.21 11.8 0.1 0.21 11.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain Nucleoside_tran PF01733.13 EEQ32409.1 - 1.8e-41 142.2 11.6 3e-39 135.0 8.0 2.3 1 1 0 1 1 1 1 Nucleoside transporter YfhO PF09586.5 EEQ32409.1 - 0.13 10.2 5.0 0.28 9.1 3.4 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO zf-C2H2 PF00096.21 EEQ32410.1 - 2.6e-06 27.4 6.0 0.0058 16.9 0.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ32410.1 - 0.00029 20.9 8.4 0.051 13.9 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.7 EEQ32410.1 - 0.062 13.3 0.6 0.42 10.6 0.1 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_2 PF12756.2 EEQ32410.1 - 0.07 13.2 1.2 10 6.3 0.0 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EEQ32410.1 - 0.09 12.7 4.9 2.5 8.1 0.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 EEQ32410.1 - 0.094 12.8 1.5 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Metallophos_2 PF12850.2 EEQ32411.1 - 1.4e-10 41.2 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEQ32411.1 - 3.6e-07 29.7 0.2 8.3e-07 28.5 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3635 PF12330.3 EEQ32412.1 - 2.4e-07 30.7 0.0 5.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) APH PF01636.18 EEQ32412.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2404 PF10296.4 EEQ32413.1 - 0.00011 22.2 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF1682 PF07946.9 EEQ32414.1 - 3.4e-105 351.4 0.2 4e-105 351.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) KaiA PF07688.7 EEQ32414.1 - 0.057 12.6 0.4 0.083 12.1 0.3 1.2 1 0 0 1 1 1 0 KaiA domain Gluconate_2-dh3 PF13618.1 EEQ32414.1 - 0.059 13.5 1.6 0.12 12.5 1.1 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 PBP_sp32 PF07222.7 EEQ32414.1 - 1.1 8.3 7.0 1.5 7.8 4.9 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF2992 PF11208.3 EEQ32414.1 - 6 6.7 15.8 10 6.0 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) SYF2 PF08231.7 EEQ32417.1 - 1e-52 178.3 16.3 1e-52 178.3 11.3 2.1 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.9 EEQ32417.1 - 0.075 12.9 0.5 0.075 12.9 0.3 3.5 1 1 1 3 3 3 0 ARD/ARD' family NAD_binding_10 PF13460.1 EEQ32418.1 - 1.8e-10 41.1 0.0 1e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ32418.1 - 1.5e-07 31.1 0.0 5.1e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ32418.1 - 2.1e-05 23.3 0.0 8.1e-05 21.4 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EEQ32418.1 - 9.9e-05 22.3 0.1 0.00051 19.9 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EEQ32418.1 - 0.0034 16.3 0.4 0.15 10.9 0.3 3.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EEQ32418.1 - 0.033 13.0 0.0 0.15 10.9 0.0 2.0 3 0 0 3 3 3 0 RmlD substrate binding domain NmrA PF05368.8 EEQ32418.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Pox_RNA_Pol_19 PF05320.7 EEQ32418.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit YEATS PF03366.11 EEQ32419.1 - 1.8e-35 120.4 0.5 2.7e-35 119.9 0.3 1.3 1 0 0 1 1 1 1 YEATS family Cid2 PF09774.4 EEQ32419.1 - 0.029 14.4 0.3 0.041 13.9 0.2 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 Cgr1 PF03879.9 EEQ32419.1 - 0.088 12.9 2.7 0.16 12.1 1.9 1.4 1 0 0 1 1 1 0 Cgr1 family Rep_fac_C PF08542.6 EEQ32420.1 - 6.4e-22 77.3 0.1 1.5e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EEQ32420.1 - 3.3e-11 43.1 0.0 2.7e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EEQ32420.1 - 4.4e-11 43.1 0.0 7.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEQ32420.1 - 7.2e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ32420.1 - 7.2e-06 26.1 0.0 0.00017 21.6 0.0 2.4 1 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EEQ32420.1 - 1e-05 24.7 0.0 2.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EEQ32420.1 - 1.5e-05 23.9 0.0 0.051 12.2 0.0 2.5 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EEQ32420.1 - 2.2e-05 24.5 0.1 0.036 14.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EEQ32420.1 - 2.3e-05 24.0 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EEQ32420.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EEQ32420.1 - 0.00059 19.3 0.0 0.085 12.2 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 EEQ32420.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DEAD PF00270.24 EEQ32420.1 - 0.0018 17.8 0.1 0.19 11.2 0.0 2.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.1 EEQ32420.1 - 0.0019 17.8 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EEQ32420.1 - 0.002 17.5 0.1 0.1 12.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EEQ32420.1 - 0.0024 17.0 0.0 0.027 13.6 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EEQ32420.1 - 0.0047 16.6 0.2 0.033 13.8 0.1 2.2 1 1 1 2 2 2 1 NTPase ArgK PF03308.11 EEQ32420.1 - 0.0087 14.8 0.1 0.022 13.5 0.0 1.5 1 1 1 2 2 2 1 ArgK protein AAA_11 PF13086.1 EEQ32420.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ32420.1 - 0.022 15.0 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEQ32420.1 - 0.027 13.9 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 EEQ32420.1 - 0.045 12.9 0.0 0.093 11.9 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_31 PF13614.1 EEQ32420.1 - 0.084 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.17 EEQ32421.1 - 1.6e-10 40.8 0.0 2.3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1338 PF07063.8 EEQ32422.1 - 3.5e-85 285.7 0.0 4.1e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) RimM PF01782.13 EEQ32422.1 - 0.13 12.2 0.1 23 5.0 0.0 2.4 2 0 0 2 2 2 0 RimM N-terminal domain DUF410 PF04190.8 EEQ32424.1 - 2e-40 138.9 0.0 2.6e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.6 EEQ32425.1 - 7.6e-28 96.0 0.0 1.4e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.12 EEQ32426.1 - 5.4e-51 173.0 3.7 1.2e-48 165.3 2.6 3.0 1 1 0 1 1 1 1 IPP transferase AAA_33 PF13671.1 EEQ32426.1 - 8.6e-06 25.6 0.1 0.042 13.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EEQ32426.1 - 8.5e-05 23.3 0.8 0.00034 21.4 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ32426.1 - 0.00014 22.1 0.7 0.29 11.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain IPT PF01745.11 EEQ32426.1 - 0.00024 20.3 0.0 0.00056 19.1 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase zf-met PF12874.2 EEQ32426.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_25 PF13481.1 EEQ32426.1 - 0.0041 16.5 0.0 0.079 12.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain zf-C2H2_2 PF12756.2 EEQ32426.1 - 0.0093 16.0 0.4 0.05 13.7 0.0 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EEQ32426.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding VASP_tetra PF08776.6 EEQ32426.1 - 0.083 12.2 1.9 0.18 11.1 0.0 2.6 3 0 0 3 3 3 0 VASP tetramerisation domain PhoH PF02562.11 EEQ32426.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 EEQ32426.1 - 5.6 7.2 8.2 15 5.8 0.1 2.8 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EEQ32427.1 - 1.1e-17 64.5 0.2 6.2e-17 62.1 0.1 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEQ32427.1 - 2.4e-10 40.8 1.8 0.00026 21.0 0.5 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EEQ32427.1 - 2e-05 23.8 0.0 0.12 11.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEQ32427.1 - 3.3e-05 23.3 0.3 8.3e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 EEQ32427.1 - 4.6e-05 22.7 0.1 0.11 11.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EEQ32427.1 - 0.0014 18.1 0.0 0.0054 16.2 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EEQ32427.1 - 0.0024 18.2 0.1 0.0037 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEQ32427.1 - 0.0042 16.5 0.1 0.0057 16.1 0.1 1.3 1 1 0 1 1 1 1 AAA-like domain DUF258 PF03193.11 EEQ32427.1 - 0.01 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ32427.1 - 0.012 16.4 0.7 0.032 15.0 0.4 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EEQ32427.1 - 0.019 14.7 0.3 0.032 14.0 0.2 1.3 1 0 0 1 1 1 0 Dynamin family AAA_25 PF13481.1 EEQ32427.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EEQ32427.1 - 0.024 14.4 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF3584 PF12128.3 EEQ32427.1 - 0.024 11.9 0.1 0.032 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_16 PF13191.1 EEQ32427.1 - 0.034 14.1 0.8 0.065 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EEQ32427.1 - 0.063 13.1 0.1 1 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 EEQ32427.1 - 0.066 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein PduV-EutP PF10662.4 EEQ32427.1 - 0.077 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EEQ32427.1 - 0.1 12.5 0.3 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEQ32427.1 - 0.12 12.5 0.2 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2813 PF11398.3 EEQ32427.1 - 0.14 11.2 0.2 0.22 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) MMR_HSR1 PF01926.18 EEQ32427.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EEQ32427.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin WD40 PF00400.27 EEQ32428.1 - 1.6e-60 198.9 29.3 1e-09 37.8 0.0 13.9 15 0 0 15 15 15 10 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEQ32428.1 - 0.02 14.6 0.0 41 3.9 0.0 4.7 4 2 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Urm1 PF09138.6 EEQ32429.1 - 8e-34 115.6 0.0 9.3e-34 115.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EEQ32429.1 - 0.037 14.4 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.13 EEQ32430.1 - 1.5e-61 207.3 0.0 2.4e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEQ32430.1 - 7.4e-21 74.8 0.4 1.1e-20 74.3 0.3 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EEQ32430.1 - 0.00016 22.4 0.1 0.00052 20.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ32430.1 - 0.0072 16.2 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EEQ32430.1 - 0.066 12.8 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.5 EEQ32430.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Porin_3 PF01459.17 EEQ32431.1 - 3.1e-79 266.1 0.0 3.5e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 EEQ32431.1 - 0.013 14.8 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.20 EEQ32432.1 - 2.5e-62 210.3 0.0 3.4e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32432.1 - 3.5e-24 85.2 0.0 4.4e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ32432.1 - 8.7e-07 28.1 0.0 2e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ32432.1 - 0.0023 17.7 0.2 0.019 14.6 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ32432.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 EEQ32433.1 - 4.8e-81 270.7 0.2 1.9e-80 268.8 0.0 2.0 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 EEQ32433.1 - 1.2e-53 181.9 0.5 2.5e-53 180.8 0.0 1.7 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.14 EEQ32433.1 - 0.0015 18.0 1.1 0.0055 16.1 0.0 2.4 4 0 0 4 4 4 1 MIF4G domain MscS_TM PF12794.2 EEQ32433.1 - 0.038 12.6 0.0 0.35 9.4 0.0 2.4 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 FA_hydroxylase PF04116.8 EEQ32434.1 - 1.5e-13 51.1 17.3 1.5e-13 51.1 12.0 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily WD40 PF00400.27 EEQ32435.1 - 1.9e-72 236.7 12.8 6.4e-12 44.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EEQ32435.1 - 3.4e-26 91.2 10.1 5.1e-26 90.6 7.0 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EEQ32435.1 - 3.8e-06 25.4 2.1 0.00024 19.5 0.2 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EEQ32435.1 - 0.00065 19.4 0.0 0.063 12.9 0.0 2.7 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEQ32435.1 - 0.0066 14.6 0.1 0.15 10.1 0.1 2.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 EEQ32435.1 - 0.014 14.5 0.0 5.4 6.0 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EEQ32435.1 - 0.021 13.5 0.1 1.6 7.4 0.1 3.2 2 1 1 3 3 3 0 Nup133 N terminal like MMS1_N PF10433.4 EEQ32435.1 - 0.21 9.6 0.0 8.1 4.4 0.0 2.4 1 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term zf-C2H2 PF00096.21 EEQ32437.1 - 5e-18 64.2 23.0 7.9e-05 22.7 0.7 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ32437.1 - 9.4e-18 63.5 22.9 1.1e-07 31.7 1.6 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ32437.1 - 7e-14 51.0 19.1 0.0024 18.0 0.6 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EEQ32437.1 - 0.00038 20.5 7.0 0.5 10.6 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Mito_carr PF00153.22 EEQ32438.1 - 1.8e-62 207.0 1.0 1.7e-20 72.5 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EEQ32439.1 - 1e-34 117.9 0.0 2.2e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ32439.1 - 8.3e-18 64.1 0.0 1.1e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ32439.1 - 7.2e-15 54.5 0.0 5.3e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEQ32439.1 - 0.0071 16.0 0.3 0.51 10.1 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 DUF3720 PF12517.3 EEQ32439.1 - 0.042 14.5 4.8 0.15 12.7 3.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Cas_Cas2CT1978 PF09707.5 EEQ32439.1 - 0.058 13.3 0.0 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.6 EEQ32439.1 - 0.13 11.8 0.1 9.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain CMV_1a_C PF12503.3 EEQ32439.1 - 0.13 12.0 0.2 17 5.2 0.0 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein C terminal DUF605 PF04652.11 EEQ32439.1 - 3.8 6.7 11.8 4.7 6.5 8.2 1.2 1 0 0 1 1 1 0 Vta1 like DUF2015 PF09435.5 EEQ32440.1 - 1.1e-42 144.8 0.0 1.2e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EEQ32441.1 - 3e-37 127.6 0.1 4.1e-37 127.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.18 EEQ32442.1 - 1.4e-40 138.3 0.0 2.8e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EEQ32442.1 - 1.7e-37 128.7 0.0 2.3e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 EEQ32442.1 - 0.097 11.9 0.0 0.25 10.6 0.0 1.6 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 EEQ32443.1 - 4.2e-25 88.0 3.6 4.2e-12 45.8 1.9 3.0 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component PorB PF11565.3 EEQ32443.1 - 0.06 13.5 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha helical Porin B Glyco_transf_90 PF05686.7 EEQ32444.1 - 5.4e-20 71.4 6.2 1.1e-14 53.9 4.2 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 PINIT PF14324.1 EEQ32445.1 - 3.7e-42 143.8 0.5 7.2e-42 142.8 0.3 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EEQ32445.1 - 1.2e-21 75.9 7.0 2.6e-21 74.8 4.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EEQ32445.1 - 7.6e-08 31.6 0.2 1.9e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 EEQ32445.1 - 4.2e-05 22.9 2.7 9.1e-05 21.9 1.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 EEQ32445.1 - 0.023 14.2 0.1 0.072 12.6 0.0 1.8 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF2423 PF10338.4 EEQ32446.1 - 2.3e-18 65.8 2.3 2.3e-18 65.8 1.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Hypoth_Ymh PF09509.5 EEQ32446.1 - 0.031 13.9 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) HeLo PF14479.1 EEQ32446.1 - 0.11 12.2 1.1 0.13 11.9 0.8 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation Phosphodiest PF01663.17 EEQ32447.1 - 3.8e-17 62.6 0.8 1.5e-15 57.4 0.6 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EEQ32447.1 - 0.15 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily YqzE PF14038.1 EEQ32448.1 - 0.0093 15.6 0.7 0.025 14.3 0.5 1.7 1 0 0 1 1 1 1 YqzE-like protein Mlp PF03304.8 EEQ32448.1 - 0.81 9.6 5.9 3.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Mlp lipoprotein family RRM_2 PF04059.7 EEQ32450.1 - 9e-35 118.5 0.6 1.7e-34 117.7 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EEQ32450.1 - 3.9e-09 36.0 0.2 0.0011 18.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ32450.1 - 0.0028 17.4 0.1 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ32450.1 - 0.037 14.0 0.2 0.57 10.2 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ins_P5_2-kin PF06090.7 EEQ32451.1 - 1.1e-59 202.0 0.0 1.4e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4444 PF14563.1 EEQ32451.1 - 0.02 14.3 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Creb_binding PF09030.5 EEQ32451.1 - 0.085 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Creb binding Sec15 PF04091.7 EEQ32452.1 - 7.8e-113 376.8 0.3 7.8e-113 376.8 0.2 2.7 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like COG2 PF06148.6 EEQ32452.1 - 0.00087 19.1 5.0 0.00087 19.1 3.4 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 EEQ32452.1 - 0.0047 15.8 5.3 0.012 14.5 3.7 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EEQ32452.1 - 0.071 12.8 5.5 0.13 11.9 1.4 2.8 3 0 0 3 3 3 0 Exocyst complex component Sec5 PMEI PF04043.10 EEQ32452.1 - 0.13 12.1 1.7 0.19 11.6 0.4 1.8 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Sec8_exocyst PF04048.9 EEQ32452.1 - 0.6 9.7 11.3 0.039 13.5 3.1 2.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain CBFD_NFYB_HMF PF00808.18 EEQ32453.1 - 5.4e-19 68.0 0.5 9.3e-19 67.2 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ32453.1 - 2.1e-12 46.9 0.1 3.2e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EEQ32453.1 - 0.029 14.1 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.6 EEQ32454.1 - 1.8e-14 53.5 0.2 5.4e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing DUF1938 PF09153.5 EEQ32454.1 - 0.079 12.7 0.1 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) DUF89 PF01937.14 EEQ32454.1 - 0.11 11.3 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF89 tRNA-synt_1b PF00579.20 EEQ32455.1 - 3.9e-66 223.1 0.0 7.6e-66 222.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.17 EEQ32455.1 - 4.7e-25 87.2 0.0 1.6e-24 85.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e TRL PF13146.1 EEQ32455.1 - 0.19 11.7 0.1 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 TRL-like protein family SWIRM PF04433.12 EEQ32457.1 - 4.2e-15 55.6 0.0 1.4e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain MSA-2c PF12238.3 EEQ32457.1 - 4 7.0 6.9 7.6 6.1 4.8 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c CDC50 PF03381.10 EEQ32458.1 - 2.1e-101 338.7 0.1 2.7e-101 338.3 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.6 EEQ32459.1 - 2.7e-59 199.3 0.1 7.1e-59 198.0 0.1 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EEQ32459.1 - 1.7e-55 187.0 0.1 4.8e-55 185.5 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EEQ32459.1 - 2.1e-24 86.2 0.0 3.4e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EEQ32459.1 - 3.1e-19 68.7 0.0 8.8e-19 67.2 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Mito_carr PF00153.22 EEQ32460.1 - 1.8e-19 69.2 0.1 8.7e-13 47.8 0.0 2.8 2 0 0 2 2 2 2 Mitochondrial carrier protein GST_N_3 PF13417.1 EEQ32462.1 - 6.4e-08 32.7 0.0 1.5e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ32462.1 - 1.6e-07 31.2 0.1 3.8e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ32462.1 - 1.7e-05 24.6 0.1 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ32462.1 - 7.3e-05 23.1 0.1 0.00013 22.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEQ32462.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain VitK2_biosynth PF02621.9 EEQ32462.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Menaquinone biosynthesis Sugar_tr PF00083.19 EEQ32463.1 - 2.3e-103 346.1 17.1 2.7e-103 345.9 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ32463.1 - 1.6e-32 112.6 46.1 3.8e-30 104.8 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEQ32463.1 - 4.1e-11 41.9 15.6 5.2e-07 28.4 1.0 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EEQ32463.1 - 0.14 10.2 4.9 0.86 7.6 0.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector PMT PF02366.13 EEQ32464.1 - 4.7e-86 288.1 15.9 4.7e-86 288.1 11.0 2.8 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEQ32464.1 - 1.2e-38 132.6 0.2 1.6e-38 132.1 0.1 1.2 1 0 0 1 1 1 1 MIR domain HECA PF15353.1 EEQ32465.1 - 0.049 13.3 0.9 0.32 10.7 0.1 2.5 2 1 0 2 2 2 0 Headcase protein family homologue Ras PF00071.17 EEQ32467.1 - 1.5e-47 160.9 0.1 1.7e-36 125.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EEQ32467.1 - 1.2e-16 61.2 0.0 1.6e-10 41.5 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 EEQ32467.1 - 1.7e-08 33.9 0.1 2.1e-07 30.3 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ32467.1 - 4.4e-08 32.7 0.0 1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEQ32467.1 - 9.8e-06 24.8 0.1 6.3e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ32467.1 - 0.0005 20.0 0.0 0.0035 17.2 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2201_N PF13203.1 EEQ32467.1 - 0.025 13.7 0.1 0.035 13.2 0.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain AAA_22 PF13401.1 EEQ32467.1 - 0.043 13.9 0.1 0.3 11.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EEQ32467.1 - 0.07 12.3 0.1 0.2 10.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ32467.1 - 0.23 11.4 1.9 0.51 10.2 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 EEQ32468.1 - 2.9e-24 85.6 0.0 7.9e-24 84.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32468.1 - 1.5e-12 47.1 0.0 4.8e-07 29.1 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EEQ32468.1 - 0.0082 15.9 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Dsh_C PF12316.3 EEQ32469.1 - 0.09 12.8 0.5 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Choline_transpo PF04515.7 EEQ32470.1 - 2.6e-12 46.1 16.4 2.6e-12 46.1 11.4 3.0 3 0 0 3 3 3 1 Plasma-membrane choline transporter Aldo_ket_red PF00248.16 EEQ32472.1 - 5e-45 153.4 0.0 6.3e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 EEQ32473.1 - 4.9e-100 335.1 0.0 5e-99 331.8 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family V_ATPase_I PF01496.14 EEQ32474.1 - 2.3 5.9 4.2 3.2 5.5 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF3_subunit PF08597.5 EEQ32474.1 - 7.5 6.0 19.2 1.3 8.5 9.6 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit zf-CCHC PF00098.18 EEQ32475.1 - 1.2e-43 145.0 54.9 2.8e-07 30.1 1.5 7.2 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EEQ32475.1 - 7.5e-12 44.7 39.7 0.018 14.7 0.6 7.0 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EEQ32475.1 - 0.00079 19.1 45.1 0.074 12.8 0.2 6.6 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 EEQ32475.1 - 0.053 13.2 42.3 0.19 11.4 0.3 6.8 4 2 3 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 EEQ32475.1 - 2.6 7.6 35.6 2 7.9 0.2 7.0 3 2 4 7 7 7 0 Zinc knuckle F-box PF00646.28 EEQ32476.1 - 0.00038 20.0 0.5 0.00085 18.9 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ32476.1 - 0.00058 19.5 0.2 0.0013 18.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EEQ32476.1 - 0.0056 16.5 0.1 6.3 6.8 0.1 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat SAE2 PF08573.5 EEQ32477.1 - 8.2e-22 77.7 1.8 1.7e-20 73.4 0.0 3.1 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Microtub_assoc PF07989.6 EEQ32477.1 - 0.023 14.5 4.6 1.5 8.6 0.7 3.0 2 1 1 3 3 3 0 Microtubule associated AF1Q PF15017.1 EEQ32477.1 - 0.027 14.3 3.8 3.5 7.5 0.0 3.9 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator DUF2855 PF11017.3 EEQ32477.1 - 0.044 12.9 0.2 0.072 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) APG6 PF04111.7 EEQ32477.1 - 0.16 11.0 8.0 0.29 10.1 5.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Pex16 PF08610.5 EEQ32478.1 - 4.1e-114 381.0 0.2 4.7e-114 380.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 EEQ32479.1 - 7.9e-39 133.3 0.0 1e-34 119.9 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII Mif2_N PF15624.1 EEQ32480.1 - 3.8e-42 144.1 2.9 3.8e-42 144.1 2.0 3.8 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EEQ32480.1 - 4.7e-33 113.0 1.5 4.7e-33 113.0 1.1 1.9 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.6 EEQ32480.1 - 2.9e-05 23.4 0.0 6.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain CAP_GLY PF01302.20 EEQ32481.1 - 2.3e-27 94.4 0.0 3.8e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EEQ32481.1 - 1e-16 60.9 0.0 1.9e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EEQ32481.1 - 4e-06 26.1 0.0 8.1e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.7 EEQ32482.1 - 9.3e-12 45.2 0.0 1.6e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ32482.1 - 1e-07 31.8 0.0 2.3e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ32482.1 - 7e-06 26.4 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ32482.1 - 2.6e-05 23.8 0.0 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ32482.1 - 3.6e-05 24.0 0.0 6.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ32482.1 - 0.003 18.1 0.0 0.0066 17.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EEQ32482.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Myb_DNA-binding PF00249.26 EEQ32483.1 - 1.7e-10 40.7 2.4 1.1e-07 31.8 0.1 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ32483.1 - 8.8e-08 32.1 5.1 0.00012 22.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Ribosomal_S30 PF04758.9 EEQ32485.1 - 0.065 12.9 0.3 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein S30 UCH PF00443.24 EEQ32486.1 - 3.5e-36 124.6 0.9 5.3e-36 124.1 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ32486.1 - 5.9e-24 85.0 0.3 1.1e-23 84.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EEQ32486.1 - 3.5e-05 23.2 6.0 0.013 14.7 0.3 3.2 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase GFA PF04828.9 EEQ32486.1 - 0.02 14.8 0.8 0.043 13.7 0.6 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme SWIM PF04434.12 EEQ32487.1 - 0.087 12.3 8.4 0.089 12.2 0.2 2.6 2 0 0 2 2 2 0 SWIM zinc finger MitMem_reg PF13012.1 EEQ32488.1 - 2.4e-39 133.9 0.1 2.4e-39 133.9 0.0 2.0 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EEQ32488.1 - 5e-28 97.1 0.0 1.1e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PGA2 PF07543.7 EEQ32488.1 - 0.045 13.5 3.1 0.078 12.7 2.2 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 ADK PF00406.17 EEQ32489.1 - 8.1e-55 184.8 0.1 1e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EEQ32489.1 - 1.9e-14 52.9 0.0 4.4e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EEQ32489.1 - 0.00052 19.9 0.0 0.00088 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EEQ32489.1 - 0.0025 17.1 0.1 0.005 16.2 0.1 1.4 1 0 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.1 EEQ32489.1 - 0.012 16.4 0.0 0.02 15.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEQ32489.1 - 0.015 14.4 0.2 0.028 13.4 0.1 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EEQ32489.1 - 0.024 14.9 0.1 0.063 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain CFIA_Pcf11 PF11526.3 EEQ32491.1 - 3.5e-05 23.8 1.8 3.5e-05 23.8 1.3 2.0 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.8 EEQ32491.1 - 0.00064 19.9 0.0 0.0023 18.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.14 EEQ32491.1 - 0.0026 17.3 0.0 0.0075 15.9 0.0 1.7 1 0 0 1 1 1 1 VHS domain RRN7 PF11781.3 EEQ32491.1 - 0.0033 16.8 2.4 0.033 13.7 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 MULE PF10551.4 EEQ32491.1 - 0.069 13.3 0.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 MULE transposase domain zf-ISL3 PF14690.1 EEQ32491.1 - 0.41 10.7 3.1 0.37 10.8 0.5 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_4 PF13894.1 EEQ32491.1 - 1.9 8.9 3.8 15 6.1 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EEQ32491.1 - 5.2 6.8 7.0 13 5.5 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EEQ32491.1 - 6.1 6.8 5.3 23 5.0 1.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger HOOK PF05622.7 EEQ32492.1 - 3.6e-21 74.6 37.4 3.6e-21 74.6 25.9 2.5 1 1 1 2 2 2 1 HOOK protein Coprogen_oxidas PF01218.13 EEQ32493.1 - 1.7e-58 197.5 0.1 7.6e-35 119.8 0.0 2.3 1 1 1 2 2 2 2 Coproporphyrinogen III oxidase Med26 PF08711.6 EEQ32494.1 - 0.034 13.6 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Mnd1 PF03962.10 EEQ32494.1 - 0.083 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Mnd1 family Mito_carr PF00153.22 EEQ32495.1 - 1.8e-27 94.8 1.9 2.9e-15 55.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Apc15p PF05841.6 EEQ32497.1 - 3.6e-25 89.1 0.1 3.6e-25 89.1 0.1 2.1 2 1 1 3 3 3 1 Apc15p protein SGT1 PF07093.6 EEQ32497.1 - 0.14 10.5 16.4 0.14 10.5 11.4 1.1 1 0 0 1 1 1 0 SGT1 protein SNARE PF05739.14 EEQ32498.1 - 2.3e-08 33.5 0.9 3e-08 33.2 0.7 1.1 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EEQ32498.1 - 0.034 13.5 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF3454 PF11936.3 EEQ32498.1 - 2.2 8.5 8.7 11 6.3 3.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3454) CHZ PF09649.5 EEQ32499.1 - 3.1e-13 48.7 0.3 3.1e-13 48.7 0.2 2.7 2 1 1 3 3 3 1 Histone chaperone domain CHZ HSP70 PF00012.15 EEQ32500.1 - 1.6e-271 901.5 8.0 1.9e-271 901.3 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ32500.1 - 1.5e-16 59.9 0.1 1.2e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EEQ32500.1 - 0.0016 17.5 0.1 0.023 13.7 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EEQ32500.1 - 0.0032 17.1 0.0 0.0077 15.8 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EEQ32500.1 - 0.013 15.2 3.3 1.2 8.9 0.3 3.6 2 2 0 2 2 2 0 Cell division protein FtsA DUF1843 PF08898.5 EEQ32500.1 - 2.5 8.2 5.4 1.2 9.2 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Fungal_trans PF04082.13 EEQ32501.1 - 8.2e-29 100.2 0.7 1.3e-28 99.6 0.0 1.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ32501.1 - 0.071 13.0 15.1 0.13 12.1 10.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 EEQ32502.1 - 5.9e-29 100.9 0.3 3.1e-28 98.6 0.1 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEQ32502.1 - 1.2e-19 70.4 0.0 2.2e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 EEQ32503.1 - 2.2e-89 300.0 32.0 2.5e-89 299.8 22.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin McyA_C PF12593.3 EEQ32503.1 - 0.037 13.7 0.1 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 Microcystin synthetase C terminal Glu_synthase PF01645.12 EEQ32505.1 - 3.5e-158 526.3 0.0 5.1e-158 525.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EEQ32505.1 - 4.1e-137 456.6 0.0 6.5e-137 456.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EEQ32505.1 - 9.6e-119 395.8 0.0 1.6e-118 395.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EEQ32505.1 - 6.7e-50 168.9 2.0 5.8e-48 162.5 1.4 2.4 1 1 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EEQ32505.1 - 1.9e-22 79.0 0.0 4.9e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EEQ32505.1 - 2.8e-17 63.2 0.3 6.9e-17 61.9 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ32505.1 - 6e-10 39.5 0.6 0.00024 21.2 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ32505.1 - 1.1e-08 34.9 0.0 4.4e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEQ32505.1 - 9.6e-08 32.3 0.0 5.1e-05 23.6 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEQ32505.1 - 3.8e-06 26.2 0.2 7.9e-06 25.1 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EEQ32505.1 - 7.6e-06 25.0 1.0 0.00021 20.3 0.2 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEQ32505.1 - 6.3e-05 21.6 0.1 6.3e-05 21.6 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EEQ32505.1 - 8.1e-05 21.6 1.6 0.00051 19.0 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 EEQ32505.1 - 0.00011 21.4 0.1 0.00022 20.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEQ32505.1 - 0.0011 18.0 0.0 0.0025 16.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EEQ32505.1 - 0.0029 17.1 0.1 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DJ-1_PfpI PF01965.19 EEQ32505.1 - 0.005 16.3 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family Thi4 PF01946.12 EEQ32505.1 - 0.0084 15.2 0.1 0.0084 15.2 0.1 2.2 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.1 EEQ32505.1 - 0.015 15.5 2.0 1.1 9.5 0.1 3.0 3 0 0 3 3 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EEQ32505.1 - 0.026 14.2 0.3 0.062 13.0 0.0 1.8 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 EEQ32505.1 - 0.035 12.9 1.9 0.086 11.6 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.14 EEQ32505.1 - 0.036 12.2 0.1 1.3 7.1 0.0 2.5 2 1 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EEQ32505.1 - 0.057 13.2 0.0 0.24 11.1 0.0 2.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EEQ32505.1 - 0.18 11.8 0.1 36 4.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3128 PF11326.3 EEQ32506.1 - 5.9e-30 103.2 3.4 5.9e-30 103.2 2.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) RNA12 PF10443.4 EEQ32507.1 - 2.3e-146 487.7 0.1 3.6e-146 487.0 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EEQ32507.1 - 0.0002 21.1 0.1 0.0013 18.4 0.1 2.1 1 1 0 1 1 1 1 Archaeal ATPase DUF2487 PF10673.4 EEQ32507.1 - 0.002 17.9 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) RRM_1 PF00076.17 EEQ32507.1 - 0.0081 15.7 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ32507.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 EEQ32508.1 - 0.41 8.8 23.1 0.52 8.4 16.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 p450 PF00067.17 EEQ32509.1 - 6.1e-07 28.3 0.0 0.003 16.1 0.0 2.5 2 0 0 2 2 2 2 Cytochrome P450 Doppel PF11466.3 EEQ32509.1 - 0.053 13.0 0.6 0.15 11.6 0.4 1.8 1 0 0 1 1 1 0 Prion-like protein Doppel WD40 PF00400.27 EEQ32510.1 - 7.2e-23 79.5 8.1 2.4e-10 39.8 0.0 7.8 7 1 1 8 8 8 4 WD domain, G-beta repeat DUF3639 PF12341.3 EEQ32510.1 - 3.2e-11 43.0 1.4 3.2e-11 43.0 0.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EEQ32510.1 - 1.4e-08 34.0 0.0 2e-07 30.1 0.0 2.2 1 1 1 2 2 2 1 Coatomer WD associated region DUF3312 PF11768.3 EEQ32510.1 - 1.5e-05 23.4 0.0 0.019 13.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) eIF2A PF08662.6 EEQ32510.1 - 0.00012 21.7 0.2 0.00079 19.1 0.0 2.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EEQ32510.1 - 0.0021 15.9 0.1 0.0049 14.7 0.1 1.5 1 1 0 1 1 1 1 IKI3 family DNA_pol_alpha_N PF12254.3 EEQ32510.1 - 0.01 15.6 1.6 0.035 13.9 1.1 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal MFS_1 PF07690.11 EEQ32512.1 - 4.7e-37 127.5 14.9 4.7e-37 127.5 10.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ32512.1 - 6.9e-09 34.7 7.5 1.1e-07 30.8 5.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF791 PF05631.9 EEQ32512.1 - 0.0012 17.6 0.6 0.0022 16.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) LacY_symp PF01306.14 EEQ32512.1 - 0.015 13.9 0.4 0.028 12.9 0.3 1.4 1 0 0 1 1 1 0 LacY proton/sugar symporter MFS_2 PF13347.1 EEQ32512.1 - 0.12 10.7 13.8 0.0041 15.5 3.1 2.2 2 0 0 2 2 2 0 MFS/sugar transport protein DUF1129 PF06570.6 EEQ32512.1 - 0.53 9.5 3.2 5.2 6.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) APH PF01636.18 EEQ32513.1 - 7.9e-10 38.8 0.0 2.1e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ32513.1 - 0.0005 19.2 0.2 0.1 11.7 0.0 2.4 2 0 0 2 2 2 2 Ecdysteroid kinase DUF2347 PF09804.4 EEQ32514.1 - 0.094 11.9 3.3 0.18 11.0 2.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4298 PF14131.1 EEQ32514.1 - 0.12 12.2 5.3 0.055 13.3 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DASH_Hsk3 PF08227.6 EEQ32514.1 - 0.23 11.7 4.4 0.27 11.4 0.3 2.7 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like GRP PF07172.6 EEQ32514.1 - 0.53 10.7 25.0 2.3 8.7 17.3 2.2 1 0 0 1 1 1 0 Glycine rich protein family FlxA PF14282.1 EEQ32514.1 - 0.91 9.5 18.7 32 4.5 10.4 3.4 2 1 0 2 2 2 0 FlxA-like protein CTNNB1_binding PF08347.6 EEQ32514.1 - 3.7 7.7 8.2 6.6 6.9 5.7 1.8 1 1 0 1 1 1 0 N-terminal CTNNB1 binding CBFD_NFYB_HMF PF00808.18 EEQ32515.1 - 9.6e-05 22.3 0.1 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone VTC PF09359.5 EEQ32516.1 - 4.2e-86 288.4 0.0 6.7e-86 287.8 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EEQ32516.1 - 6.5e-24 85.1 4.3 4.8e-17 62.6 0.8 3.0 1 1 1 2 2 2 2 SPX domain 6PF2K PF01591.13 EEQ32517.1 - 9.8e-68 227.5 0.0 1.1e-45 155.4 0.0 2.1 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEQ32517.1 - 1.3e-15 57.8 0.0 1.1e-14 54.8 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EEQ32517.1 - 1e-05 25.4 0.0 0.042 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEQ32517.1 - 0.0058 17.4 0.0 0.019 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF202 PF02656.10 EEQ32518.1 - 0.0018 18.4 3.0 0.0079 16.3 2.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF202) FMN_dh PF01070.13 EEQ32519.1 - 2.3e-101 339.2 0.1 3e-101 338.8 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEQ32519.1 - 3.1e-22 78.1 0.0 1.4e-21 76.0 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EEQ32519.1 - 1.1e-06 27.8 0.1 2.1e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EEQ32519.1 - 2.1e-06 26.8 0.3 0.0015 17.5 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EEQ32519.1 - 0.023 13.9 0.1 0.099 11.8 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.10 EEQ32519.1 - 0.028 13.5 4.4 0.079 12.0 0.6 2.6 1 1 1 2 2 2 0 Nitronate monooxygenase Na_H_Exchanger PF00999.16 EEQ32521.1 - 3.1e-37 128.0 15.1 4.3e-37 127.5 10.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GFO_IDH_MocA PF01408.17 EEQ32522.1 - 2e-22 79.9 0.0 3.6e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_23 PF13489.1 EEQ32523.1 - 1.3e-13 51.0 0.1 2.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ32523.1 - 1.3e-05 24.8 0.2 0.012 15.2 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ32523.1 - 0.027 15.0 0.2 10 6.7 0.1 2.4 1 1 1 2 2 2 0 Methyltransferase domain ERG4_ERG24 PF01222.12 EEQ32524.1 - 1.5e-143 478.4 22.4 1.8e-143 478.2 15.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4 PF00097.20 EEQ32525.1 - 4e-06 26.3 9.7 7.5e-06 25.5 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ32525.1 - 5.7e-06 26.2 11.7 9.8e-06 25.5 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ32525.1 - 0.00011 21.8 8.0 0.00017 21.1 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ32525.1 - 0.00011 21.9 10.5 0.00022 20.9 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ32525.1 - 0.0006 19.4 7.0 0.0013 18.4 4.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEQ32525.1 - 0.00081 19.2 9.8 0.0049 16.7 6.9 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ32525.1 - 0.5 10.1 9.4 1.2 8.8 6.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger GAGA PF09237.6 EEQ32525.1 - 4.3 7.0 6.6 1.1 8.9 1.4 2.3 2 0 0 2 2 2 0 GAGA factor UCH PF00443.24 EEQ32526.1 - 6.7e-46 156.5 0.0 1.3e-45 155.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ32526.1 - 8.2e-24 84.5 0.0 2.1e-23 83.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HNOBA PF07701.9 EEQ32526.1 - 0.099 11.8 0.0 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 Heme NO binding associated DLH PF01738.13 EEQ32528.1 - 4e-05 23.0 0.0 4.5e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family CFIA_Pcf11 PF11526.3 EEQ32529.1 - 2.2 8.4 5.6 0.52 10.4 1.0 2.1 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Chs3p PF12271.3 EEQ32530.1 - 2.8e-95 318.7 7.1 3.4e-95 318.4 4.9 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Cytochrom_B_N PF00033.14 EEQ32530.1 - 0.32 10.3 8.5 1 8.6 5.9 2.0 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF202 PF02656.10 EEQ32530.1 - 0.45 10.7 0.0 0.45 10.7 0.0 4.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF1129 PF06570.6 EEQ32530.1 - 1.7 7.8 7.0 0.55 9.5 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) MpPF26 PF07666.6 EEQ32530.1 - 7.7 6.4 16.7 0.04 13.8 2.6 3.1 2 2 1 3 3 3 0 M penetrans paralogue family 26 Glyoxalase_2 PF12681.2 EEQ32531.1 - 7.1e-10 39.4 0.0 8.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EEQ32531.1 - 0.00023 21.1 0.1 0.00065 19.6 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BC10 PF06726.7 EEQ32532.1 - 3.9e-17 62.0 9.9 7.5e-17 61.1 6.9 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 dCMP_cyt_deam_1 PF00383.17 EEQ32534.1 - 6e-06 25.8 0.0 1.5e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.6 EEQ32535.1 - 4e-28 98.6 0.0 1e-27 97.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EEQ32535.1 - 0.00029 20.3 0.0 0.00029 20.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Macoilin PF09726.4 EEQ32535.1 - 0.58 8.3 9.2 0.76 7.9 6.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Arm PF00514.18 EEQ32536.1 - 1.3e-16 59.6 9.1 0.0077 16.0 0.7 8.6 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEQ32536.1 - 4.1e-05 23.7 7.2 0.089 13.0 0.0 5.6 6 0 0 6 6 6 2 HEAT repeats Ric8 PF10165.4 EEQ32536.1 - 0.004 16.0 0.3 0.044 12.6 0.0 2.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor synembryn HEAT PF02985.17 EEQ32536.1 - 0.017 15.1 12.5 2.2 8.5 0.0 6.5 7 0 0 7 7 7 0 HEAT repeat adh_short PF00106.20 EEQ32537.1 - 0.018 14.9 0.0 0.085 12.7 0.0 2.0 2 1 0 2 2 2 0 short chain dehydrogenase Fructosamin_kin PF03881.9 EEQ32538.1 - 8.2e-61 205.4 0.0 2.1e-60 204.1 0.0 1.6 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EEQ32538.1 - 0.028 14.1 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GST_N_3 PF13417.1 EEQ32539.1 - 1.4e-20 73.2 0.3 4e-20 71.8 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ32539.1 - 5.4e-14 51.9 0.0 1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-C2H2 PF00096.21 EEQ32540.1 - 4e-14 52.0 26.6 0.00045 20.4 0.1 8.4 7 1 1 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEQ32540.1 - 3e-09 36.7 39.9 0.0015 18.6 0.3 7.2 8 1 1 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ32540.1 - 7.1e-08 32.3 30.7 0.037 14.2 0.1 7.4 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEQ32540.1 - 0.00031 20.5 22.5 0.0048 16.7 0.0 6.7 6 1 1 7 7 7 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EEQ32540.1 - 0.0088 16.2 1.2 0.0088 16.2 0.8 7.2 8 0 0 8 8 8 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EEQ32540.1 - 0.087 13.1 42.1 2.8 8.4 5.1 8.4 8 1 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EEQ32540.1 - 0.097 12.7 42.2 1.2 9.2 3.6 5.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF3133 PF11331.3 EEQ32540.1 - 0.58 9.7 15.4 0.045 13.3 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) Cyclin_N PF00134.18 EEQ32541.1 - 2.2e-10 40.1 0.2 3.4e-09 36.3 0.0 2.5 3 0 0 3 3 3 1 Cyclin, N-terminal domain CTP_transf_1 PF01148.15 EEQ32542.1 - 5.1e-82 275.4 26.4 6.1e-82 275.1 18.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.3 EEQ32543.1 - 2.9e-55 185.9 0.0 7.9e-55 184.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Atg14 PF10186.4 EEQ32543.1 - 0.017 14.0 1.7 0.039 12.8 1.2 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4164 PF13747.1 EEQ32543.1 - 0.024 14.7 1.7 0.024 14.7 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF1192 PF06698.6 EEQ32543.1 - 0.03 14.1 3.2 0.087 12.6 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Takusan PF04822.8 EEQ32543.1 - 0.033 13.9 1.8 0.086 12.6 1.3 1.8 1 0 0 1 1 1 0 Takusan DUF4140 PF13600.1 EEQ32543.1 - 0.43 11.0 9.1 0.12 12.8 2.2 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 EEQ32543.1 - 0.81 8.6 10.4 1.6 7.7 7.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 FA_desaturase PF00487.19 EEQ32544.1 - 5.9e-09 35.7 18.1 5.9e-09 35.7 12.6 2.2 1 1 1 2 2 2 1 Fatty acid desaturase EI24 PF07264.6 EEQ32544.1 - 2.3e-05 23.9 0.5 2.3e-05 23.9 0.3 1.9 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) GDPD PF03009.12 EEQ32545.1 - 1.1e-17 64.4 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MFS_1 PF07690.11 EEQ32546.1 - 1.1e-17 63.7 18.7 5.7e-16 58.1 5.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Fst_toxin PF13955.1 EEQ32546.1 - 0.22 11.2 2.6 0.68 9.6 1.8 1.9 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system Sterol_MT_C PF08498.5 EEQ32547.1 - 4.7e-24 84.1 0.3 7.3e-24 83.4 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 EEQ32547.1 - 2.8e-19 69.2 0.0 4.1e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ32547.1 - 4e-18 65.7 0.0 9.1e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEQ32547.1 - 1.9e-13 50.1 0.0 2.7e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EEQ32547.1 - 2e-13 50.3 0.0 3.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ32547.1 - 1.3e-12 48.2 0.0 3.9e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ32547.1 - 1.9e-12 47.4 0.0 4.4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ32547.1 - 4.5e-10 39.8 0.1 1.2e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ32547.1 - 8.1e-10 38.2 0.0 1.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEQ32547.1 - 3.4e-08 33.5 0.0 1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ32547.1 - 1.8e-06 27.6 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EEQ32547.1 - 3.8e-05 23.3 0.1 5.6e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EEQ32547.1 - 0.00033 20.0 0.0 0.00066 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain B PF02216.11 EEQ32547.1 - 0.0058 16.3 0.1 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 B domain PrmA PF06325.8 EEQ32547.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EEQ32547.1 - 0.02 13.9 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EEQ32547.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EEQ32547.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 adh_short PF00106.20 EEQ32548.1 - 1.3e-11 44.7 0.0 4.2e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EEQ32548.1 - 3.9e-05 22.7 0.0 7.9e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 EEQ32548.1 - 0.001 18.7 0.0 0.0026 17.4 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EEQ32548.1 - 0.0089 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ32548.1 - 0.017 14.5 0.0 0.52 9.7 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEQ32548.1 - 0.043 12.7 0.0 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EEQ32548.1 - 0.061 13.6 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 EEQ32550.1 - 4.5e-31 107.8 28.4 4.5e-31 107.8 19.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PDGLE PF13190.1 EEQ32550.1 - 0.36 10.5 0.0 0.36 10.5 0.0 3.0 3 0 0 3 3 3 0 PDGLE domain Prominin PF05478.6 EEQ32550.1 - 0.5 7.8 0.7 0.74 7.2 0.5 1.1 1 0 0 1 1 1 0 Prominin Methyltransf_26 PF13659.1 EEQ32552.1 - 8.3e-14 51.6 0.0 2.7e-12 46.7 0.0 2.8 2 2 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ32552.1 - 1.5e-09 38.3 0.0 3.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ32552.1 - 2.7e-09 36.8 0.0 4.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ32552.1 - 2.7e-06 27.6 0.0 4.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.7 EEQ32552.1 - 3.7e-06 26.3 0.0 4.7e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF890) MTS PF05175.9 EEQ32552.1 - 1.8e-05 24.1 0.0 0.00053 19.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EEQ32552.1 - 0.00026 20.1 0.0 0.00039 19.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.11 EEQ32552.1 - 0.0018 17.4 0.0 0.0044 16.1 0.0 1.6 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.7 EEQ32552.1 - 0.0042 17.5 0.0 0.0082 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ32552.1 - 0.0052 15.9 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EEQ32552.1 - 0.021 15.3 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.3 EEQ32552.1 - 0.065 12.2 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa UPF0020 PF01170.13 EEQ32552.1 - 0.091 12.3 0.0 3.1 7.3 0.0 2.5 3 0 0 3 3 3 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EEQ32552.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.18 EEQ32553.1 - 1e-61 208.9 0.1 1.5e-61 208.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEQ32553.1 - 3.5e-07 30.3 0.1 1.4e-05 25.1 0.0 2.8 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEQ32553.1 - 9.6e-07 29.2 1.5 0.002 18.5 0.2 4.1 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EEQ32553.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EEQ32553.1 - 0.054 13.3 0.2 5 7.0 0.0 2.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease zf-C2H2_jaz PF12171.3 EEQ32556.1 - 0.0098 16.0 1.0 0.63 10.2 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ32556.1 - 0.75 10.0 9.3 8.9 6.6 0.8 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF77 PF01910.12 EEQ32557.1 - 8.6e-29 99.0 0.5 1e-28 98.7 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 TPR_8 PF13181.1 EEQ32558.1 - 7.3e-05 22.2 5.1 0.47 10.3 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ32558.1 - 0.0013 19.2 3.1 6.7 7.6 0.3 4.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ32558.1 - 0.0059 16.2 6.4 2.1 8.0 0.0 3.6 4 0 0 4 4 4 1 TPR repeat TPR_16 PF13432.1 EEQ32558.1 - 0.0093 16.6 4.1 13 6.6 0.9 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 EEQ32558.1 - 0.0096 15.7 0.1 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_21 PF09976.4 EEQ32558.1 - 0.025 14.5 1.9 8.4 6.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ32558.1 - 0.048 13.5 9.4 6.8 6.6 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ32558.1 - 0.071 13.0 8.7 2.5 8.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ32558.1 - 0.21 11.4 3.6 17 5.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 EEQ32558.1 - 0.64 10.7 4.9 11 6.8 0.0 3.6 3 0 0 3 3 3 0 Sel1 repeat TPR_19 PF14559.1 EEQ32558.1 - 0.82 10.0 4.0 9.9 6.5 0.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat PH_10 PF15411.1 EEQ32560.1 - 1e-24 86.9 0.2 1.7e-24 86.2 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EEQ32560.1 - 3.7e-08 33.2 0.0 2.1e-07 30.7 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EEQ32560.1 - 2.1e-07 30.8 0.0 4.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EEQ32560.1 - 2e-06 27.5 5.7 3.9e-06 26.5 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ32560.1 - 0.00035 20.2 4.1 0.00061 19.4 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ32560.1 - 0.00065 19.3 1.8 0.0011 18.5 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ32560.1 - 0.0051 16.8 5.1 0.0093 15.9 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ32560.1 - 0.012 15.7 1.8 0.023 14.8 1.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEQ32560.1 - 0.045 13.4 4.4 0.083 12.5 3.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.24 EEQ32560.1 - 0.079 13.1 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 PH domain PH_5 PF15405.1 EEQ32560.1 - 0.1 12.5 0.1 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain zf-RING-like PF08746.6 EEQ32560.1 - 0.54 10.3 4.2 1 9.3 2.9 1.5 1 0 0 1 1 1 0 RING-like domain Ribosomal_L12 PF00542.14 EEQ32561.1 - 5.3e-20 71.1 8.9 1e-18 67.0 4.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EEQ32561.1 - 0.0032 17.8 5.4 0.0032 17.8 3.7 2.2 2 1 0 2 2 2 1 60s Acidic ribosomal protein DFP PF04127.10 EEQ32561.1 - 0.032 13.8 0.4 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein YejG PF13989.1 EEQ32561.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein Cpn60_TCP1 PF00118.19 EEQ32562.1 - 3.8e-131 438.0 2.3 4.5e-131 437.8 1.6 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2052 PF09747.4 EEQ32562.1 - 0.0028 17.6 0.6 0.0048 16.8 0.4 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) BSP_II PF05432.6 EEQ32562.1 - 0.013 14.8 4.4 0.021 14.1 3.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 EEQ32562.1 - 0.035 13.6 7.1 0.07 12.6 5.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EEQ32562.1 - 0.094 12.5 2.7 0.26 11.1 1.9 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 EEQ32562.1 - 0.12 11.6 1.2 0.18 11.0 0.8 1.2 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 EEQ32562.1 - 0.15 11.1 6.5 0.35 9.9 4.0 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 EEQ32562.1 - 0.5 9.9 6.9 1.2 8.7 4.8 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EEQ32562.1 - 1.1 7.9 9.9 1.8 7.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Dicty_REP PF05086.7 EEQ32562.1 - 2.9 5.5 4.2 4 5.0 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop14 PF04147.7 EEQ32562.1 - 3 5.6 7.3 4.8 4.9 5.0 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 EEQ32562.1 - 3.4 7.9 10.3 7.5 6.8 7.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain E1_dh PF00676.15 EEQ32563.1 - 8.5e-113 376.0 0.4 1e-112 375.7 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EEQ32563.1 - 3.7e-05 22.8 0.1 6.9e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 EEQ32563.1 - 4.4 8.0 7.9 4.9 7.8 0.5 2.7 2 1 0 2 2 2 0 KRTAP type 7 family S4 PF01479.20 EEQ32565.1 - 5.5e-16 57.7 0.0 1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EEQ32565.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 S4 domain SSP160 PF06933.6 EEQ32565.1 - 0.33 8.8 10.3 0.45 8.4 7.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Hid1 PF12722.2 EEQ32565.1 - 0.42 8.2 8.3 0.59 7.7 5.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPV_P10 PF05531.7 EEQ32565.1 - 0.43 10.8 2.4 2.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3439 PF11921.3 EEQ32565.1 - 0.64 9.7 7.8 0.68 9.6 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dak2 PF02734.12 EEQ32565.1 - 1.1 8.9 9.1 0.82 9.3 5.0 1.8 1 1 0 1 1 1 0 DAK2 domain Pex14_N PF04695.8 EEQ32565.1 - 1.6 8.7 11.5 2 8.4 6.6 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3138 PF11336.3 EEQ32565.1 - 2.7 6.0 8.6 3.9 5.5 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Abhydrolase_6 PF12697.2 EEQ32566.1 - 2.3e-31 109.4 0.2 2.9e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ32566.1 - 1.2e-14 54.4 0.1 2.2e-13 50.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ32566.1 - 1.4e-12 47.5 0.0 3.2e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ32566.1 - 1.5e-05 24.6 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EEQ32566.1 - 0.0053 16.2 0.2 0.012 15.0 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EEQ32566.1 - 0.014 15.6 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydro_lipase PF04083.11 EEQ32566.1 - 0.023 14.0 0.0 0.06 12.7 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_2 PF02230.11 EEQ32566.1 - 0.028 13.8 0.0 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EEQ32566.1 - 0.039 13.5 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.7 EEQ32566.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.3 EEQ32566.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase AA_permease_2 PF13520.1 EEQ32567.1 - 2.4e-64 217.4 44.6 3.3e-64 217.0 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ32567.1 - 2.5e-28 98.6 31.3 2.5e-28 98.6 21.7 2.1 2 0 0 2 2 2 2 Amino acid permease NAD_binding_1 PF00175.16 EEQ32568.1 - 3.8e-06 27.4 0.0 0.001 19.5 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEQ32568.1 - 5.1e-06 26.5 0.0 1.6e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEQ32568.1 - 0.028 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Aminotran_5 PF00266.14 EEQ32569.1 - 3.3e-24 85.3 0.0 1.3e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.15 EEQ32570.1 - 5.6e-71 239.4 0.4 5.3e-45 153.7 0.1 2.8 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEQ32570.1 - 3.9e-23 81.9 0.0 9.6e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Peptidase_M22 PF00814.20 EEQ32571.1 - 8e-84 281.2 0.0 1e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family SET PF00856.23 EEQ32572.1 - 3.9e-13 50.0 0.0 1.7e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EEQ32572.1 - 1.2e-07 31.7 0.1 2.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding EPL1 PF10513.4 EEQ32573.1 - 4.1e-31 108.3 0.8 4.1e-31 108.3 0.6 3.1 2 1 1 3 3 3 1 Enhancer of polycomb-like DUF2535 PF10751.4 EEQ32573.1 - 0.065 13.3 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2535) EF-hand_1 PF00036.27 EEQ32574.1 - 1.2e-26 89.9 12.3 1.4e-07 30.2 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEQ32574.1 - 2.9e-22 78.5 3.0 8.4e-12 45.0 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEQ32574.1 - 2.1e-20 70.7 5.3 5.5e-05 22.7 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEQ32574.1 - 3.3e-18 64.1 12.7 1.5e-06 27.2 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EEQ32574.1 - 1.2e-14 53.6 14.6 1.3e-05 24.7 0.5 4.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EEQ32574.1 - 4.7e-06 26.6 0.0 0.0029 17.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EEQ32574.1 - 8e-05 22.3 9.0 0.014 15.0 0.2 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EEQ32574.1 - 0.021 14.6 0.1 0.55 10.1 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain Ribosomal_S9 PF00380.14 EEQ32577.1 - 1.2e-35 122.3 0.9 1.8e-35 121.8 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 EEQ32578.1 - 1.4e-46 156.6 0.2 2.2e-46 155.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EEQ32578.1 - 2.3e-12 46.7 0.0 6.6e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ32578.1 - 1.6e-08 34.6 0.0 3.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEQ32578.1 - 2.6e-08 33.9 0.0 7.6e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ32578.1 - 4.3e-08 32.9 0.0 9.9e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ32578.1 - 3.8e-06 27.3 0.0 7.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEQ32578.1 - 2.4e-05 24.2 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2360 PF10152.4 EEQ32578.1 - 0.039 14.2 2.2 0.055 13.7 1.5 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) NIF PF03031.13 EEQ32579.1 - 3.5e-24 85.2 1.6 1.1e-23 83.7 1.1 1.8 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 EEQ32580.1 - 5.6e-42 143.4 26.9 5.6e-42 143.4 18.7 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF947) Cut8_N PF14482.1 EEQ32582.1 - 0.12 12.3 2.3 0.38 10.7 0.1 2.1 2 0 0 2 2 2 0 Cut8 proteasome-binding domain DUF1757 PF08560.5 EEQ32583.1 - 1.3e-05 24.9 0.0 1.5e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) LGT PF01790.13 EEQ32583.1 - 0.0069 15.3 0.8 0.034 13.0 0.5 1.8 1 1 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase AMPKBI PF04739.10 EEQ32584.1 - 9.5e-22 76.7 0.1 3.1e-21 75.1 0.0 1.9 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4399 PF14347.1 EEQ32584.1 - 0.078 13.0 0.2 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) Mannosyl_trans3 PF11051.3 EEQ32586.1 - 1.7e-73 247.3 0.0 4.5e-73 245.9 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative ABC1 PF03109.11 EEQ32587.1 - 1.2e-32 112.3 0.0 3.1e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 ABC1 family UreF PF01730.11 EEQ32588.1 - 4.5e-06 26.8 3.0 1.5e-05 25.1 2.0 1.9 1 1 0 1 1 1 1 UreF DUF1138 PF06592.8 EEQ32588.1 - 0.014 15.3 0.0 2.3 8.3 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1138) DUF4145 PF13643.1 EEQ32588.1 - 0.099 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) BRE1 PF08647.6 EEQ32589.1 - 2.9e-24 84.8 14.5 2.9e-24 84.8 10.0 6.4 5 1 1 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EEQ32589.1 - 1.4e-09 37.8 10.7 2.4e-09 37.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ32589.1 - 6e-09 35.4 8.4 1.1e-08 34.6 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ32589.1 - 7.8e-08 31.8 10.8 1.5e-07 30.9 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ32589.1 - 2.3e-07 30.5 8.3 4.5e-07 29.5 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ32589.1 - 2.8e-06 26.9 11.4 5.1e-06 26.1 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Reo_sigmaC PF04582.7 EEQ32589.1 - 7.2e-06 25.4 38.8 0.00032 20.0 2.4 4.6 2 1 3 5 5 5 3 Reovirus sigma C capsid protein zf-RING_UBOX PF13445.1 EEQ32589.1 - 8.8e-06 25.3 6.5 3.5e-05 23.4 4.5 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEQ32589.1 - 0.0018 18.1 7.2 0.0034 17.2 5.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EEQ32589.1 - 0.0038 17.2 3.3 0.011 15.7 2.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EEQ32589.1 - 0.035 13.7 7.7 0.13 11.8 5.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EEQ32589.1 - 0.04 13.7 5.6 0.092 12.6 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 EEQ32589.1 - 0.048 13.2 3.6 0.1 12.1 2.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EEQ32589.1 - 0.13 12.0 4.0 0.26 11.1 2.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 EEQ32589.1 - 0.14 11.7 6.2 0.38 10.3 4.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pox_A_type_inc PF04508.7 EEQ32589.1 - 0.93 9.4 12.9 18 5.4 0.0 7.3 6 0 0 6 6 5 0 Viral A-type inclusion protein repeat DZR PF12773.2 EEQ32589.1 - 0.97 9.2 6.1 2.4 8.0 4.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 EEQ32589.1 - 1.3 9.0 12.9 24 4.8 8.4 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2 PF00096.21 EEQ32589.1 - 6.3 7.3 8.3 1.5 9.3 0.3 3.2 3 0 0 3 3 2 0 Zinc finger, C2H2 type Myb_DNA-binding PF00249.26 EEQ32590.1 - 0.00018 21.5 0.0 0.0019 18.1 0.0 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF1183 PF06682.7 EEQ32591.1 - 9.9e-78 261.9 10.3 2.5e-77 260.6 7.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) DUF2404 PF10296.4 EEQ32592.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ARD PF03079.9 EEQ32593.1 - 3.6e-47 160.2 0.3 4.2e-47 159.9 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EEQ32593.1 - 5e-09 35.5 0.2 7.8e-09 34.9 0.1 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EEQ32593.1 - 1.3e-05 24.8 0.1 2.1e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EEQ32593.1 - 0.00053 19.4 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EEQ32593.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GIDA PF01134.17 EEQ32594.1 - 9.9e-155 515.2 0.0 1.3e-154 514.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EEQ32594.1 - 6.3e-18 64.6 0.0 1.7e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EEQ32594.1 - 1.9e-09 37.6 0.2 3.7e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEQ32594.1 - 5.5e-06 25.7 0.3 7.7e-06 25.2 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EEQ32594.1 - 1.5e-05 24.0 1.4 0.031 13.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ32594.1 - 0.00037 19.4 0.8 0.00072 18.5 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EEQ32594.1 - 0.013 14.1 0.1 0.67 8.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EEQ32594.1 - 0.016 13.6 1.4 0.088 11.2 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EEQ32594.1 - 0.09 12.3 0.5 0.19 11.2 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EEQ32594.1 - 0.13 12.0 0.1 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3605 PF12239.3 EEQ32595.1 - 1.4e-44 151.7 3.6 2.6e-44 150.8 2.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) APH PF01636.18 EEQ32596.1 - 1e-16 61.3 0.1 1.9e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Neuromodulin_N PF10580.4 EEQ32596.1 - 0.3 10.7 1.5 3.1 7.5 0.1 2.7 3 0 0 3 3 3 0 Gap junction protein N-terminal region Sec1 PF00995.18 EEQ32597.1 - 9.2e-151 503.2 0.0 1.1e-150 503.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family adh_short PF00106.20 EEQ32598.1 - 3.4e-22 79.1 0.0 4.7e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ32598.1 - 6.9e-12 45.3 0.0 1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ32598.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEQ32598.1 - 0.00013 21.0 0.0 0.00028 19.8 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEQ32598.1 - 0.00023 21.2 0.0 0.00048 20.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEQ32598.1 - 0.00027 19.9 0.0 0.00034 19.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EEQ32598.1 - 0.0015 17.3 0.0 0.002 16.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EEQ32598.1 - 0.0063 15.7 0.0 0.014 14.6 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 EEQ32598.1 - 0.043 12.7 0.0 14 4.4 0.0 2.9 2 1 1 3 3 3 0 Male sterility protein Synaptonemal_3 PF15191.1 EEQ32598.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 NAD_binding_8 PF13450.1 EEQ32599.1 - 2.3e-12 46.7 0.1 8.3e-12 44.9 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ32599.1 - 8.4e-09 34.7 0.0 4.2e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ32599.1 - 3.2e-07 30.4 0.1 0.0015 18.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ32599.1 - 4e-06 25.9 0.1 2.2e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EEQ32599.1 - 5.2e-06 26.6 0.1 0.00012 22.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ32599.1 - 3.4e-05 23.0 0.0 6.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EEQ32599.1 - 3.5e-05 22.4 0.3 0.00057 18.4 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EEQ32599.1 - 5.1e-05 23.6 0.2 0.045 14.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEQ32599.1 - 8.7e-05 21.7 0.1 0.00084 18.5 0.0 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EEQ32599.1 - 0.0011 17.7 0.6 0.016 13.8 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 EEQ32599.1 - 0.0027 16.8 0.0 0.0096 15.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEQ32599.1 - 0.0036 16.2 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EEQ32599.1 - 0.01 14.9 0.0 0.043 12.8 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EEQ32599.1 - 0.01 15.5 0.4 0.047 13.4 0.0 2.3 3 0 0 3 3 2 0 FAD-NAD(P)-binding ApbA PF02558.11 EEQ32599.1 - 0.03 13.7 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EEQ32599.1 - 0.063 12.1 0.1 0.093 11.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.16 EEQ32599.1 - 0.11 12.2 0.2 0.24 11.2 0.0 1.7 2 0 0 2 2 1 0 ThiF family Malic_M PF03949.10 EEQ32599.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Tyr-DNA_phospho PF06087.7 EEQ32600.1 - 6.2e-46 156.9 0.0 1e-45 156.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 EEQ32600.1 - 3 7.6 17.1 0.47 10.1 2.4 3.2 3 0 0 3 3 3 0 Ubiquitin interaction motif Gti1_Pac2 PF09729.4 EEQ32601.1 - 4.1e-63 212.2 0.6 5e-62 208.6 0.0 2.3 2 1 0 2 2 2 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.16 EEQ32602.1 - 7.3e-18 64.7 5.2 1.3e-17 63.9 3.6 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase LysR_substrate PF03466.15 EEQ32602.1 - 0.12 11.5 0.1 0.64 9.0 0.0 1.9 2 0 0 2 2 2 0 LysR substrate binding domain MBOAT PF03062.14 EEQ32603.1 - 1.1e-47 162.6 4.5 2e-47 161.9 3.1 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_60s PF00428.14 EEQ32603.1 - 1.9 8.9 9.5 4.3 7.7 6.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Abi PF02517.11 EEQ32605.1 - 4.3e-14 52.4 4.4 4.3e-14 52.4 3.0 2.6 3 1 0 3 3 3 1 CAAX protease self-immunity Suc_Fer-like PF06999.7 EEQ32606.1 - 3.6e-48 164.6 0.0 4.1e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF2531 PF10748.4 EEQ32606.1 - 0.005 16.0 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2531) zf-C2H2_2 PF12756.2 EEQ32607.1 - 1.3e-20 73.4 4.1 1e-19 70.4 2.4 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EEQ32607.1 - 0.0097 16.0 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type tRNA-synt_1 PF00133.17 EEQ32608.1 - 1.5e-57 194.9 0.0 3.1e-36 124.5 0.0 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EEQ32608.1 - 1.2e-37 129.0 0.0 1.9e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EEQ32608.1 - 7.6e-33 113.7 0.1 1.7e-25 89.5 0.0 4.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEQ32608.1 - 1.5e-13 50.7 0.0 3.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EEQ32608.1 - 1.3e-06 27.7 0.0 7.1e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EEQ32608.1 - 0.0013 17.6 0.0 0.0021 16.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 EEQ32608.1 - 0.01 14.5 0.2 2.8 6.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Cation_ATPase_C PF00689.16 EEQ32609.1 - 0.0099 15.4 0.8 0.015 14.8 0.5 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus 2-Hacid_dh_C PF02826.14 EEQ32611.1 - 6e-50 168.8 0.0 9.1e-50 168.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ32611.1 - 2.9e-16 59.1 0.0 4.3e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEQ32611.1 - 0.00043 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase FH2 PF02181.18 EEQ32614.1 - 4.2e-81 272.6 5.0 4.2e-81 272.6 3.4 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EEQ32614.1 - 1.7e-67 226.4 0.0 1.7e-67 226.4 0.0 2.3 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EEQ32614.1 - 7e-28 97.3 0.5 5.6e-21 74.8 0.0 3.8 1 1 2 3 3 3 3 Diaphanous FH3 Domain TrmE_N PF10396.4 EEQ32616.1 - 1.9e-35 121.3 0.0 4.2e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EEQ32616.1 - 1.1e-20 73.8 0.5 4.2e-20 71.9 0.1 2.2 2 1 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EEQ32616.1 - 1e-15 57.6 0.0 1.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEQ32616.1 - 1.1e-05 25.2 0.1 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 EEQ32616.1 - 1.6e-05 24.4 0.0 0.0014 18.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEQ32616.1 - 7.2e-05 22.1 0.2 0.00037 19.7 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EEQ32616.1 - 0.00015 22.2 0.0 0.00047 20.6 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Glyco_hydro_3_C PF01915.17 EEQ32616.1 - 0.023 14.2 0.1 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain ABC_tran PF00005.22 EEQ32616.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter RNA_pol_L_2 PF13656.1 EEQ32617.1 - 4.7e-31 106.0 0.0 6.6e-31 105.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEQ32617.1 - 1.3e-12 46.6 0.0 1.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.1 EEQ32618.1 - 1.1e-06 29.0 0.4 1.4e-06 28.7 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEQ32618.1 - 0.00015 21.4 0.4 0.00036 20.2 0.3 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ32618.1 - 0.00084 19.5 0.3 0.0012 18.9 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Abhydrolase_6 PF12697.2 EEQ32620.1 - 1.5e-15 57.7 0.0 2.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ32620.1 - 1.2e-10 41.3 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ32620.1 - 2.2e-09 37.2 0.0 4.7e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EEQ32620.1 - 0.0098 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DLH PF01738.13 EEQ32620.1 - 0.02 14.1 0.0 1.2 8.3 0.0 2.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.17 EEQ32620.1 - 0.038 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase Zn_clus PF00172.13 EEQ32621.1 - 0.00034 20.4 9.0 0.0013 18.6 6.3 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CEP170_C PF15308.1 EEQ32621.1 - 0.096 10.9 0.2 0.71 8.0 0.0 1.9 2 0 0 2 2 2 0 CEP170 C-terminus MFS_1 PF07690.11 EEQ32622.1 - 1.2e-33 116.3 26.1 1.2e-33 116.3 18.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ32622.1 - 2.3e-11 42.9 4.6 2.3e-11 42.9 3.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter RseC_MucC PF04246.7 EEQ32622.1 - 8.8 5.9 10.7 2.7 7.5 1.1 3.3 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Beta_elim_lyase PF01212.16 EEQ32623.1 - 2.4e-55 187.7 0.1 2.9e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EEQ32623.1 - 0.0023 16.2 0.0 0.0033 15.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEQ32623.1 - 0.029 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Trp_DMAT PF11991.3 EEQ32624.1 - 9.3e-121 403.4 0.0 2.4e-120 402.0 0.0 1.6 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase TRAPPC9-Trs120 PF08626.6 EEQ32625.1 - 1e-145 486.8 0.0 4.3e-145 484.7 0.0 1.8 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CARDB PF07705.6 EEQ32625.1 - 0.046 13.7 0.0 12 5.9 0.0 3.0 3 0 0 3 3 3 0 CARDB DUF3684 PF12449.3 EEQ32626.1 - 0 1545.0 0.0 0 1544.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EEQ32626.1 - 3.1e-05 23.6 0.0 8.6e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEQ32626.1 - 0.0065 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.5 EEQ32626.1 - 0.19 11.6 8.7 0.14 11.9 0.1 2.9 3 0 0 3 3 3 0 WLM domain Pro-kuma_activ PF09286.6 EEQ32627.1 - 7.3e-39 133.0 1.3 1.3e-38 132.2 0.9 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEQ32627.1 - 3.5e-07 29.6 0.0 5.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Subtilase family RdRP PF05183.7 EEQ32630.1 - 2.1e-163 545.1 0.0 2.9e-163 544.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Med6 PF04934.9 EEQ32631.1 - 8.8e-42 141.9 0.0 3.5e-41 140.0 0.0 1.8 2 0 0 2 2 2 1 MED6 mediator sub complex component Lysine_decarbox PF03641.9 EEQ32632.1 - 4.2e-30 104.2 0.0 6.6e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase Mito_carr PF00153.22 EEQ32632.1 - 0.09 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial carrier protein DAGK_acc PF00609.14 EEQ32632.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase accessory domain Proteasome PF00227.21 EEQ32633.1 - 1.9e-49 167.5 0.3 2.7e-49 167.0 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEQ32633.1 - 9.7e-12 43.9 1.5 1.3e-11 43.5 0.2 2.0 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 EEQ32634.1 - 1.8e-45 153.5 7.4 2e-45 153.4 5.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2798 PF11391.3 EEQ32634.1 - 0.29 10.9 0.2 0.29 10.9 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2798) UPF0220 PF05255.6 EEQ32636.1 - 9.9e-66 220.0 5.6 1.1e-65 219.9 3.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) G3P_antiterm PF04309.7 EEQ32636.1 - 0.079 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Fes1 PF08609.5 EEQ32637.1 - 1.1e-31 109.1 4.7 4.8e-31 107.1 1.9 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EEQ32637.1 - 2.3e-16 59.8 4.9 6.6e-09 35.9 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EEQ32637.1 - 4.7e-09 36.4 0.2 4.2e-06 27.0 0.0 3.1 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EEQ32637.1 - 2.2e-08 33.4 0.1 0.0006 19.6 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat Arm PF00514.18 EEQ32637.1 - 1.4e-06 27.8 0.0 0.016 15.0 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EEQ32637.1 - 0.0005 18.5 0.1 0.00098 17.5 0.0 1.4 2 0 0 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.1 EEQ32637.1 - 0.00053 19.8 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 FliT PF05400.8 EEQ32637.1 - 0.0084 16.4 1.1 0.28 11.6 0.0 3.1 3 1 0 3 3 3 1 Flagellar protein FliT V-ATPase_H_N PF03224.9 EEQ32637.1 - 0.043 12.9 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H DUF1856 PF08983.5 EEQ32637.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) Actin PF00022.14 EEQ32638.1 - 6.3e-159 528.6 0.0 7.1e-159 528.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EEQ32638.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_18 PF00704.23 EEQ32639.1 - 1.7e-76 257.9 12.0 2.1e-76 257.6 8.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GARS_A PF01071.14 EEQ32640.1 - 2.4e-84 281.7 0.0 3.9e-84 281.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EEQ32640.1 - 5e-35 119.9 0.1 5.8e-34 116.5 0.0 2.9 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EEQ32640.1 - 2.1e-30 105.7 0.0 4.3e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EEQ32640.1 - 2.5e-26 91.6 0.5 5.7e-26 90.5 0.4 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EEQ32640.1 - 2e-16 59.9 2.8 6.7e-16 58.3 1.2 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EEQ32640.1 - 2.2e-09 37.3 0.0 8.6e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEQ32640.1 - 6.1e-08 31.7 0.0 1.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EEQ32640.1 - 2.9e-05 23.4 0.0 6.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EEQ32640.1 - 5.6e-05 23.0 0.0 0.0003 20.6 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EEQ32640.1 - 0.00084 18.6 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EEQ32640.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Pet127 PF08634.5 EEQ32641.1 - 1.9e-115 384.7 0.2 2.6e-115 384.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 SOR PF07682.6 EEQ32641.1 - 0.039 12.5 0.0 0.064 11.8 0.0 1.2 1 0 0 1 1 1 0 Sulphur oxygenase reductase LRR_6 PF13516.1 EEQ32643.1 - 0.0048 16.8 3.2 81 3.7 0.0 6.7 6 0 0 6 6 6 2 Leucine Rich repeat Gly_transf_sug PF04488.10 EEQ32645.1 - 2.7e-18 66.2 0.0 4.9e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EEQ32645.1 - 0.19 10.1 2.0 0.87 7.9 0.4 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Abhydrolase_6 PF12697.2 EEQ32646.1 - 6.6e-07 29.4 2.8 1e-06 28.8 2.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family GSHPx PF00255.14 EEQ32647.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione peroxidase Bul1_N PF04425.7 EEQ32648.1 - 5.1e-09 35.1 2.3 2.6e-07 29.5 1.6 2.1 1 1 0 1 1 1 1 Bul1 N terminus Arrestin_N PF00339.24 EEQ32648.1 - 0.0003 20.6 0.0 0.00099 18.9 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EEQ32648.1 - 0.0037 16.5 0.0 0.0091 15.2 0.0 1.6 2 0 0 2 2 2 1 Bul1 C terminus Abhydrolase_5 PF12695.2 EEQ32649.1 - 7.4e-10 38.7 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ32649.1 - 2.9e-08 33.8 0.3 7.8e-08 32.4 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ32649.1 - 0.0011 18.6 0.1 0.57 9.6 0.0 2.4 2 1 1 3 3 3 2 alpha/beta hydrolase fold DLH PF01738.13 EEQ32649.1 - 0.015 14.5 0.0 0.035 13.3 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EEQ32649.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EEQ32649.1 - 0.025 13.7 0.0 0.089 12.0 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EEQ32649.1 - 0.053 13.0 0.0 0.095 12.2 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 EEQ32649.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Cutinase AA_permease PF00324.16 EEQ32650.1 - 7.3e-137 456.5 47.3 9e-137 456.2 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ32650.1 - 2.5e-38 131.7 50.0 3.1e-38 131.4 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EEQ32651.1 - 5.5e-20 71.3 26.8 6.9e-20 71.0 18.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Bacillus_PapR PF05968.6 EEQ32651.1 - 0.032 14.2 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Bacillus PapR protein p450 PF00067.17 EEQ32653.1 - 1e-59 202.3 0.0 1.3e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.15 EEQ32654.1 - 6.2e-19 69.1 0.0 1.7e-18 67.7 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EEQ32654.1 - 2.5e-09 37.3 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ32654.1 - 3.3e-05 23.6 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEQ32654.1 - 0.0058 16.0 0.0 0.008 15.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EEQ32654.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cytokin_check_N PF10407.4 EEQ32655.1 - 0.00032 20.2 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Pkinase PF00069.20 EEQ32656.1 - 2.7e-43 148.0 0.0 4.8e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EEQ32656.1 - 5.7e-42 142.6 0.0 1.2e-41 141.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EEQ32656.1 - 2e-21 76.2 0.0 1.4e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.16 EEQ32656.1 - 0.00056 19.3 0.0 0.077 12.5 0.0 3.0 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.9 EEQ32656.1 - 0.0013 17.8 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEQ32656.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pro_isomerase PF00160.16 EEQ32657.1 - 7e-50 169.2 0.1 1.5e-49 168.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EEQ32657.1 - 5.2e-12 45.1 2.0 0.0032 17.2 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 EEQ32658.1 - 8.9e-129 430.2 9.5 1.1e-128 429.9 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Csm1 PF12539.3 EEQ32659.1 - 0.085 13.3 0.1 1.6 9.2 0.0 2.6 3 0 0 3 3 3 0 Chromosome segregation protein Csm1/Pcs1 Pam17 PF08566.5 EEQ32661.1 - 4.4e-71 238.1 0.1 5.8e-71 237.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2076 PF09849.4 EEQ32661.1 - 0.02 14.9 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TMEM52 PF14979.1 EEQ32661.1 - 0.03 14.2 1.6 0.049 13.5 1.1 1.3 1 0 0 1 1 1 0 Transmembrane 52 Beta_elim_lyase PF01212.16 EEQ32661.1 - 0.041 13.0 0.0 0.056 12.5 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Fungal_trans_2 PF11951.3 EEQ32662.1 - 2.2e-51 174.6 0.0 3.4e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ32662.1 - 6.1e-06 26.0 5.9 9.9e-06 25.3 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIB PF02201.13 EEQ32663.1 - 1.3e-21 76.0 0.0 2.6e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EEQ32663.1 - 4.5e-14 51.9 0.2 1.1e-13 50.7 0.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain eIF2A PF08662.6 EEQ32664.1 - 5.9e-39 133.7 5.8 7.8e-37 126.8 0.8 4.2 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 EEQ32664.1 - 8.4e-08 31.9 0.0 2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ32664.1 - 4.7e-07 29.3 0.0 1.3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ32664.1 - 2.8e-06 27.2 0.0 9.6e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EEQ32664.1 - 0.00042 20.0 0.3 0.21 11.5 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat DLH PF01738.13 EEQ32665.1 - 3.2e-28 98.5 0.0 4.8e-27 94.6 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEQ32665.1 - 0.0045 16.7 0.0 0.036 13.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ32665.1 - 0.016 15.0 0.0 0.049 13.4 0.0 1.5 1 1 1 2 2 2 0 Alpha/beta hydrolase family NmrA PF05368.8 EEQ32666.1 - 2.2e-13 50.0 0.0 2.8e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ32666.1 - 6.6e-06 26.2 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEQ32666.1 - 0.0082 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Peptidase_S10 PF00450.17 EEQ32667.1 - 3.9e-124 414.9 0.3 4.8e-124 414.6 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEQ32667.1 - 0.0012 18.8 0.0 0.0028 17.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ32668.1 - 6e-22 78.3 0.0 1.6e-19 70.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ32668.1 - 3.1e-20 73.0 0.2 6.6e-20 71.9 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ32668.1 - 1.2e-08 34.8 0.0 2.8e-07 30.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEQ32668.1 - 0.00024 20.8 0.0 0.00058 19.6 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EEQ32668.1 - 0.0069 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.9 EEQ32668.1 - 0.11 10.9 0.0 0.19 10.1 0.0 1.3 1 1 0 1 1 1 0 Ndr family zf-C2H2 PF00096.21 EEQ32669.1 - 0.43 11.0 5.7 0.87 10.0 0.6 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF221 PF02714.10 EEQ32670.1 - 1.8e-103 345.8 22.5 1.8e-103 345.8 15.6 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEQ32670.1 - 1.4e-43 148.1 2.0 1.4e-43 148.1 1.4 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EEQ32670.1 - 4.3e-29 100.2 0.1 1.1e-28 98.9 0.1 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EEQ32670.1 - 1.2e-13 51.3 0.2 2.5e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3593 PF12159.3 EEQ32670.1 - 0.022 14.5 2.3 1.1 9.0 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) Acyl_transf_1 PF00698.16 EEQ32671.1 - 3e-15 56.3 0.0 4.5e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Choline_kinase PF01633.15 EEQ32672.1 - 0.00014 21.5 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EEQ32672.1 - 0.00095 18.9 0.0 0.00095 18.9 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ32672.1 - 0.018 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.9 EEQ32672.1 - 0.024 13.7 0.1 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_3 PF13920.1 EEQ32673.1 - 3e-05 23.6 9.4 3e-05 23.6 6.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.3 EEQ32673.1 - 0.13 11.9 0.2 0.34 10.6 0.1 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain MutS_V PF00488.16 EEQ32674.1 - 1.5e-73 247.0 0.8 2.3e-73 246.4 0.6 1.2 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.13 EEQ32674.1 - 1.5e-11 44.3 0.1 5.4e-11 42.5 0.1 2.1 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.13 EEQ32674.1 - 4.2e-11 43.0 0.6 7.8e-05 22.5 0.0 3.0 2 1 1 3 3 3 2 MutS domain III MutS_II PF05188.12 EEQ32674.1 - 1.9e-10 40.9 2.0 1.4e-09 38.0 0.1 2.5 2 0 0 2 2 2 1 MutS domain II WD40 PF00400.27 EEQ32675.1 - 3.9e-75 245.2 21.9 1.6e-15 56.3 0.4 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EEQ32675.1 - 5.7e-07 28.0 6.2 0.21 9.7 0.0 5.4 1 1 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EEQ32675.1 - 9.5e-07 28.7 0.1 0.2 11.3 0.0 3.8 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 EEQ32675.1 - 1.7e-05 24.7 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 EEQ32675.1 - 0.035 14.0 0.6 18 5.2 0.0 4.0 3 2 1 4 4 4 0 Siderophore-interacting FAD-binding domain TFIIIC_delta PF12657.2 EEQ32675.1 - 0.98 9.1 9.4 1.3 8.6 0.1 4.0 2 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Sec10 PF07393.6 EEQ32676.1 - 7.5e-152 507.0 0.0 9.5e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EEQ32676.1 - 4.7e-07 29.4 0.0 9.6e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ32676.1 - 1.8e-05 24.2 0.1 3.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain AAA PF00004.24 EEQ32677.1 - 3.9e-30 104.7 0.0 6.4e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ32677.1 - 2.3e-06 28.4 0.0 7e-06 26.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EEQ32677.1 - 3e-06 27.3 0.0 9.9e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ32677.1 - 5.1e-06 26.5 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EEQ32677.1 - 1.1e-05 24.9 0.1 0.0018 17.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 EEQ32677.1 - 3.4e-05 23.5 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ32677.1 - 7.1e-05 23.1 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ32677.1 - 0.00015 21.6 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ32677.1 - 0.00017 20.7 0.1 0.016 14.2 0.0 2.2 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EEQ32677.1 - 0.0002 21.0 0.0 0.00052 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 EEQ32677.1 - 0.00021 21.0 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EEQ32677.1 - 0.00038 20.5 0.0 0.00089 19.4 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.1 EEQ32677.1 - 0.0006 19.7 0.0 0.0017 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EEQ32677.1 - 0.00083 19.1 0.0 0.018 14.7 0.0 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 EEQ32677.1 - 0.0022 17.7 0.0 0.0058 16.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain UPF0079 PF02367.12 EEQ32677.1 - 0.0029 17.2 0.0 0.0081 15.7 0.0 1.7 2 0 0 2 2 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_2 PF07724.9 EEQ32677.1 - 0.0041 17.0 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 EEQ32677.1 - 0.0071 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ32677.1 - 0.0073 15.7 0.0 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEQ32677.1 - 0.018 14.2 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EEQ32677.1 - 0.027 13.4 0.0 0.058 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MobB PF03205.9 EEQ32677.1 - 0.047 13.3 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TIP49 PF06068.8 EEQ32677.1 - 0.05 12.3 0.0 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus UPF0552 PF10574.4 EEQ32677.1 - 0.054 12.9 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0552 AAA_3 PF07726.6 EEQ32677.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEQ32677.1 - 0.062 12.3 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 EEQ32677.1 - 0.072 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.21 EEQ32677.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EEQ32677.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EEQ32677.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EEQ32677.1 - 0.15 11.2 0.0 0.77 8.9 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_13 PF13166.1 EEQ32677.1 - 0.23 9.8 0.0 0.32 9.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Cytochrom_C1 PF02167.10 EEQ32678.1 - 5.6e-81 271.3 0.0 7.7e-81 270.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family SbcCD_C PF13558.1 EEQ32678.1 - 0.0013 18.5 0.2 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Cytochrome_CBB3 PF13442.1 EEQ32678.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AIG2_2 PF13772.1 EEQ32679.1 - 1e-05 25.5 0.1 3.8e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 AIG2-like family RFamide_26RFa PF11109.3 EEQ32681.1 - 0.052 13.4 0.1 0.58 10.0 0.1 2.4 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 DAHP_synth_1 PF00793.15 EEQ32682.1 - 4.2e-100 333.9 0.0 5.1e-100 333.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MFS_1 PF07690.11 EEQ32683.1 - 9.3e-10 37.7 33.3 9.3e-10 37.7 23.1 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF221 PF02714.10 EEQ32684.1 - 1.2e-96 323.3 20.0 2.2e-96 322.5 13.9 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEQ32684.1 - 5.5e-39 133.2 0.6 5.5e-39 133.2 0.5 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EEQ32684.1 - 2.9e-24 85.3 0.4 5.1e-24 84.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EEQ32684.1 - 0.0012 17.6 1.7 0.0012 17.6 1.2 2.0 3 0 0 3 3 3 1 Calcium-activated chloride channel hDGE_amylase PF14701.1 EEQ32685.1 - 1.4e-169 564.5 0.0 1.8e-169 564.1 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EEQ32685.1 - 2.1e-114 382.0 0.3 3.9e-114 381.2 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EEQ32685.1 - 4.7e-82 275.0 0.0 7.9e-82 274.3 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EEQ32685.1 - 2.5e-26 91.3 0.0 6.1e-26 90.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EEQ32685.1 - 1.3e-06 28.0 0.0 0.0024 17.3 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain RIX1 PF08167.7 EEQ32685.1 - 0.37 10.4 0.1 0.8 9.3 0.0 1.6 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis NAD_Gly3P_dh_N PF01210.18 EEQ32686.1 - 4.3e-46 156.5 0.0 6.9e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EEQ32686.1 - 4.7e-41 139.9 0.1 7.5e-41 139.3 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Slp PF03843.8 EEQ32686.1 - 0.14 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family SLX9 PF15341.1 EEQ32687.1 - 3.3e-36 124.3 1.9 5.4e-36 123.6 1.3 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 ThiF PF00899.16 EEQ32688.1 - 2.9e-40 137.2 0.0 5.7e-40 136.2 0.0 1.5 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EEQ32688.1 - 1e-24 85.9 0.2 2.4e-24 84.7 0.2 1.7 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EEQ32688.1 - 1.9e-09 37.8 0.0 3.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EEQ32688.1 - 0.0039 17.3 0.1 0.032 14.3 0.0 2.1 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EEQ32688.1 - 0.018 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.19 EEQ32688.1 - 0.024 13.5 0.1 0.05 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 EEQ32688.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EEQ32688.1 - 0.13 11.2 0.8 0.21 10.5 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain FlxA PF14282.1 EEQ32688.1 - 0.26 11.2 3.5 0.49 10.3 2.4 1.4 1 0 0 1 1 1 0 FlxA-like protein NAD_binding_11 PF14833.1 EEQ32690.1 - 9.2e-44 148.4 0.6 2.6e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EEQ32690.1 - 5.1e-37 127.2 0.0 9e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEQ32690.1 - 0.0016 18.7 0.0 0.0043 17.4 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EEQ32690.1 - 0.0027 17.3 0.1 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EEQ32690.1 - 0.038 13.4 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EEQ32690.1 - 0.14 11.5 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F_bP_aldolase PF01116.15 EEQ32691.1 - 5.1e-78 262.0 0.0 5.7e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Fer2_3 PF13085.1 EEQ32692.1 - 4.8e-32 110.0 0.0 8.6e-32 109.2 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EEQ32692.1 - 1.1e-09 38.5 5.9 1.1e-09 38.5 4.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EEQ32692.1 - 1e-08 35.0 4.2 1e-08 35.0 2.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EEQ32692.1 - 0.00014 22.2 1.0 0.00014 22.2 0.7 2.9 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEQ32692.1 - 0.00035 20.3 6.0 0.00039 20.1 2.1 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EEQ32692.1 - 0.00067 19.8 4.1 0.041 14.1 0.3 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EEQ32692.1 - 0.001 19.4 3.2 0.001 19.4 2.2 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EEQ32692.1 - 0.0025 17.5 0.3 0.0025 17.5 0.2 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EEQ32692.1 - 6.7 7.3 7.4 1.3 9.6 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain RTA1 PF04479.8 EEQ32693.1 - 6.2e-51 173.0 4.6 8e-51 172.6 3.2 1.1 1 0 0 1 1 1 1 RTA1 like protein MBOAT_2 PF13813.1 EEQ32693.1 - 0.1 12.6 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Velvet PF11754.3 EEQ32696.1 - 1.4e-43 148.8 9.4 3.3e-42 144.4 0.0 3.1 3 0 0 3 3 3 2 Velvet factor AUX_IAA PF02309.11 EEQ32696.1 - 0.041 13.6 9.3 0.077 12.7 6.4 1.4 1 0 0 1 1 1 0 AUX/IAA family Neur_chan_memb PF02932.11 EEQ32696.1 - 0.49 10.2 10.2 0.73 9.6 7.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3306 PF11748.3 EEQ32696.1 - 0.49 11.0 7.2 1 10.0 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FAM60A PF15396.1 EEQ32696.1 - 0.69 9.6 6.5 1 9.0 4.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2126 PF09899.4 EEQ32696.1 - 0.99 7.3 8.4 1.4 6.9 5.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Tim54 PF11711.3 EEQ32696.1 - 1.3 7.5 7.3 2.2 6.7 5.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.17 EEQ32696.1 - 2 7.3 22.5 2.8 6.8 15.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 EEQ32696.1 - 2.8 6.1 13.5 3.7 5.7 9.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 EEQ32696.1 - 4.7 4.7 10.5 6 4.4 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.10 EEQ32696.1 - 8.8 5.5 15.7 13 4.9 10.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Git3 PF11710.3 EEQ32697.1 - 6.5e-26 91.1 9.6 1.1e-25 90.3 6.6 1.4 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EEQ32697.1 - 1.1e-09 37.8 0.1 5.8e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EEQ32697.1 - 3.9e-08 32.7 6.2 7.1e-08 31.9 4.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EEQ32697.1 - 0.00054 18.9 6.9 0.00077 18.4 4.8 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPDPase_memb PF10110.4 EEQ32697.1 - 1.6 8.1 7.3 0.28 10.5 0.3 2.7 3 0 0 3 3 3 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Podoplanin PF05808.6 EEQ32700.1 - 0.56 9.7 0.0 0.56 9.7 0.0 3.5 3 1 0 3 3 3 0 Podoplanin UPF0370 PF13980.1 EEQ32701.1 - 0.061 13.1 0.5 3.5 7.5 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) U6-snRNA_bdg PF10596.4 EEQ32701.1 - 0.17 11.2 0.4 0.76 9.1 0.1 1.9 2 0 0 2 2 2 0 U6-snRNA interacting domain of PrP8 Herpes_UL49_5 PF05702.6 EEQ32701.1 - 0.72 9.7 4.5 0.17 11.7 0.2 2.1 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein HhH-GPD PF00730.20 EEQ32703.1 - 1.4e-10 41.3 0.0 1.8e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEQ32703.1 - 0.008 15.8 0.1 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif DUF494 PF04361.8 EEQ32703.1 - 0.037 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF494) DUF410 PF04190.8 EEQ32703.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF410) HHH_5 PF14520.1 EEQ32703.1 - 0.097 12.8 0.0 1.2 9.4 0.0 2.2 1 1 0 1 1 1 0 Helix-hairpin-helix domain Fasciclin PF02469.17 EEQ32704.1 - 5.5e-26 91.0 0.4 6.1e-13 48.8 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain G_glu_transpept PF01019.16 EEQ32705.1 - 2.6e-164 547.4 0.0 3e-164 547.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AAA PF00004.24 EEQ32707.1 - 1.6e-45 154.5 0.1 6.1e-45 152.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ32707.1 - 3.3e-09 36.5 0.1 1.1e-08 34.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ32707.1 - 4.4e-08 33.2 0.0 8.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEQ32707.1 - 4.3e-07 30.1 0.0 1.4e-06 28.4 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ32707.1 - 8.5e-07 29.1 0.6 0.00099 19.2 0.0 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EEQ32707.1 - 3.1e-06 26.2 0.0 5.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EEQ32707.1 - 0.00024 21.0 0.0 0.00055 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ32707.1 - 0.00033 19.7 0.0 0.00077 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EEQ32707.1 - 0.00048 20.1 0.0 0.00083 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEQ32707.1 - 0.00061 19.4 0.2 0.054 13.1 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EEQ32707.1 - 0.00061 20.5 0.0 0.0018 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ32707.1 - 0.00093 18.3 0.1 0.0036 16.4 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EEQ32707.1 - 0.001 19.2 0.0 0.0031 17.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_19 PF13245.1 EEQ32707.1 - 0.0014 18.3 0.2 0.0033 17.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EEQ32707.1 - 0.0019 16.9 0.0 0.0033 16.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 EEQ32707.1 - 0.0028 17.3 0.0 0.0087 15.7 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 EEQ32707.1 - 0.0036 16.9 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EEQ32707.1 - 0.0043 16.6 0.0 0.036 13.6 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EEQ32707.1 - 0.0046 16.8 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EEQ32707.1 - 0.006 15.7 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EEQ32707.1 - 0.0071 15.9 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEQ32707.1 - 0.0082 15.8 0.1 0.057 13.1 0.0 2.2 1 1 1 2 2 2 1 Archaeal ATPase AAA_30 PF13604.1 EEQ32707.1 - 0.0084 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ32707.1 - 0.0099 15.3 0.0 0.023 14.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EEQ32707.1 - 0.012 15.0 2.0 0.071 12.5 0.1 2.5 2 1 0 3 3 2 0 AAA domain AAA_24 PF13479.1 EEQ32707.1 - 0.012 15.1 0.1 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ32707.1 - 0.016 15.4 0.0 0.092 13.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 EEQ32707.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 EEQ32707.1 - 0.019 14.0 0.1 0.43 9.6 0.0 2.4 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.21 EEQ32707.1 - 0.042 13.3 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 EEQ32707.1 - 0.076 11.8 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activ_2 PF14532.1 EEQ32707.1 - 0.08 12.9 0.0 0.29 11.1 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EEQ32707.1 - 0.093 11.5 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 EEQ32707.1 - 0.13 12.6 0.0 0.77 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EEQ32707.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.18 EEQ32708.1 - 1.1e-102 343.5 0.9 1.3e-102 343.2 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEQ32708.1 - 1.5e-10 41.2 0.6 5.6e-10 39.4 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEQ32708.1 - 1.6e-06 28.5 0.3 0.0035 17.8 0.0 3.4 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EEQ32708.1 - 0.00033 20.2 0.0 0.0069 15.9 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal NIF PF03031.13 EEQ32709.1 - 1e-27 96.7 0.1 2e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EEQ32709.1 - 5.1e-12 45.4 0.2 1e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EEQ32709.1 - 8.2e-09 35.5 0.0 3.3e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain MARVEL PF01284.18 EEQ32710.1 - 0.00052 19.8 18.4 0.0012 18.6 12.6 1.8 1 1 0 1 1 1 1 Membrane-associating domain Arginase PF00491.16 EEQ32711.1 - 1.4e-76 257.4 0.9 1.7e-76 257.1 0.6 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.10 EEQ32712.1 - 6.8e-98 327.0 0.0 8.9e-98 326.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EEQ32712.1 - 1e-22 80.4 0.0 1.7e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 GatB domain Sds3 PF08598.6 EEQ32713.1 - 0.0012 18.4 1.9 0.0065 16.0 0.1 2.1 2 0 0 2 2 2 1 Sds3-like APH PF01636.18 EEQ32713.1 - 0.26 10.9 4.2 0.48 10.1 2.9 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ECH PF00378.15 EEQ32716.1 - 1.4e-49 168.4 0.1 1.7e-49 168.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pox_P21 PF05313.7 EEQ32716.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein PGAP1 PF07819.8 EEQ32718.1 - 1.8e-07 30.9 0.1 3.8e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EEQ32718.1 - 4.6e-05 22.8 0.5 0.00026 20.3 0.1 2.1 1 1 1 2 2 2 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 EEQ32718.1 - 5.3e-05 23.2 0.0 0.00016 21.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.2 EEQ32718.1 - 0.00043 20.2 0.9 0.0013 18.6 0.0 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family AAA_22 PF13401.1 EEQ32718.1 - 0.019 15.0 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEQ32718.1 - 0.028 13.5 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin YcxB PF14317.1 EEQ32718.1 - 0.039 13.2 0.1 0.093 11.9 0.0 1.6 1 0 0 1 1 1 0 YcxB-like protein DUF883 PF05957.8 EEQ32719.1 - 0.11 12.9 6.8 0.16 12.3 4.7 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Borrelia_P83 PF05262.6 EEQ32719.1 - 0.59 8.3 7.4 0.67 8.1 5.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein FHA PF00498.21 EEQ32720.1 - 1.1e-11 44.6 0.0 2.4e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain DnaJ PF00226.26 EEQ32721.1 - 1.1e-07 31.5 0.3 2e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 EEQ32722.1 - 1.8e-25 89.5 0.0 3.4e-25 88.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32722.1 - 6.7e-15 54.8 0.0 1.4e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEQ32722.1 - 0.017 14.8 0.6 0.046 13.4 0.4 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family APH PF01636.18 EEQ32723.1 - 7.2e-11 42.2 0.0 2e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family VCX_VCY PF15231.1 EEQ32723.1 - 0.18 12.1 0.1 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 Variable charge X/Y family Abhydrolase_3 PF07859.8 EEQ32725.1 - 1.8e-36 125.7 0.0 4.1e-35 121.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EEQ32725.1 - 0.0019 16.9 0.4 0.0094 14.6 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Mito_fiss_reg PF05308.6 EEQ32728.1 - 2.5 7.3 21.7 23 4.2 15.1 2.1 1 1 0 1 1 1 0 Mitochondrial fission regulator MCPVI PF02993.9 EEQ32728.1 - 4.9 7.2 11.8 8.2 6.5 8.2 1.3 1 0 0 1 1 1 0 Minor capsid protein VI HMG_box PF00505.14 EEQ32729.1 - 1.1e-24 86.4 0.5 1.9e-24 85.7 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEQ32729.1 - 2.3e-19 69.5 0.9 3.7e-19 68.8 0.6 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EEQ32729.1 - 0.00076 19.2 0.7 0.00076 19.2 0.5 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EEQ32729.1 - 0.0024 18.0 2.1 0.005 17.0 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) p450 PF00067.17 EEQ32730.1 - 2.5e-40 138.4 0.0 3.5e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Med27 PF11571.3 EEQ32730.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 27 Homoserine_dh PF00742.14 EEQ32731.1 - 4.2e-51 173.1 0.0 5.5e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EEQ32731.1 - 1.5e-11 44.7 0.0 2.9e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 EEQ32732.1 - 7e-32 109.4 10.7 7e-32 109.4 7.5 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) ATG11 PF10377.4 EEQ32733.1 - 1.4e-40 138.1 0.0 1.4e-40 138.1 0.0 3.3 2 1 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.7 EEQ32733.1 - 6.8e-10 38.3 0.1 6.8e-10 38.3 0.1 4.2 2 2 1 3 3 3 2 Autophagy protein Apg17 DUF2570 PF10828.3 EEQ32733.1 - 0.0015 18.0 4.6 0.0015 18.0 3.2 4.9 4 2 1 5 5 5 1 Protein of unknown function (DUF2570) DUF1409 PF07197.7 EEQ32733.1 - 0.014 15.4 2.9 0.1 12.6 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1409) IncA PF04156.9 EEQ32733.1 - 7.5 6.0 85.8 0.026 14.1 13.5 6.8 3 2 0 4 4 4 0 IncA protein CENP-H PF05837.7 EEQ32734.1 - 1.5e-22 79.7 7.2 1.5e-22 79.7 5.0 2.2 2 1 0 2 2 2 1 Centromere protein H (CENP-H) zf-H2C2 PF09337.5 EEQ32734.1 - 0.068 12.6 0.4 0.12 11.8 0.3 1.3 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger TPR_MLP1_2 PF07926.7 EEQ32734.1 - 2.8 7.7 11.6 0.65 9.7 3.5 2.7 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4591 PF15261.1 EEQ32735.1 - 0.045 14.0 0.6 0.07 13.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) Pex19 PF04614.7 EEQ32736.1 - 6.7e-64 215.8 17.9 6.7e-64 215.8 12.4 1.5 1 1 0 1 1 1 1 Pex19 protein family Gluconate_2-dh3 PF13618.1 EEQ32736.1 - 0.0029 17.7 5.9 2.3 8.3 0.0 3.6 1 1 2 4 4 4 2 Gluconate 2-dehydrogenase subunit 3 DUF4327 PF14217.1 EEQ32736.1 - 0.004 16.9 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4327) Radial_spoke_3 PF06098.6 EEQ32736.1 - 0.091 11.7 0.1 0.091 11.7 0.1 2.1 2 1 0 3 3 3 0 Radial spoke protein 3 FliE PF02049.13 EEQ32736.1 - 1.9 8.5 8.1 0.23 11.5 1.9 2.2 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE ASF1_hist_chap PF04729.8 EEQ32737.1 - 6.3e-68 227.2 0.0 1e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 EEQ32737.1 - 7.5 4.3 25.1 10 3.9 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.9 EEQ32738.1 - 5.1e-89 298.7 0.0 5.1e-89 298.7 0.0 3.6 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EEQ32738.1 - 0.00012 22.3 0.0 0.055 14.1 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat HAT PF02184.11 EEQ32738.1 - 0.00057 19.5 0.1 0.0026 17.4 0.0 2.2 1 0 0 1 1 1 1 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 EEQ32738.1 - 0.00073 20.1 0.0 0.044 14.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Oxysterol_BP PF01237.13 EEQ32739.1 - 1.9e-87 293.0 0.1 2.3e-87 292.7 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 EEQ32739.1 - 0.0034 17.7 0.1 0.024 15.0 0.0 2.2 2 1 1 3 3 3 1 Kinesin motor RTA1 PF04479.8 EEQ32740.1 - 1.1e-28 100.3 3.3 1.1e-28 100.3 2.3 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF1145 PF06611.7 EEQ32740.1 - 0.003 17.1 1.9 0.0038 16.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1145) CUE PF02845.11 EEQ32741.1 - 2.4e-10 39.6 0.0 3.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain Nitr_red_assoc PF09655.5 EEQ32741.1 - 0.22 11.8 0.5 0.46 10.8 0.3 1.5 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) YABBY PF04690.8 EEQ32744.1 - 2.3 8.4 5.3 3.4 7.8 3.7 1.4 1 0 0 1 1 1 0 YABBY protein SOBP PF15279.1 EEQ32744.1 - 7.2 6.8 13.1 8.1 6.7 9.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein UCH PF00443.24 EEQ32745.1 - 1.5e-41 142.3 0.2 1.1e-34 119.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ32745.1 - 2.7e-13 50.0 0.0 1.1e-12 47.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MmgE_PrpD PF03972.9 EEQ32745.1 - 0.023 12.9 0.0 0.034 12.3 0.0 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Kinesin-relat_1 PF12711.2 EEQ32745.1 - 0.036 14.4 0.1 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Kinesin motor zinc_ribbon_4 PF13717.1 EEQ32745.1 - 1.2 8.8 8.1 4 7.2 1.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EEQ32745.1 - 1.7 8.2 7.9 3.6 7.2 1.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain F_bP_aldolase PF01116.15 EEQ32747.1 - 9.2e-97 323.5 0.0 1e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Mucin PF01456.12 EEQ32749.1 - 1.9 8.2 10.9 2.3 8.0 7.5 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF221 PF02714.10 EEQ32751.1 - 6.8e-90 301.2 18.0 1.2e-89 300.4 12.5 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEQ32751.1 - 2.2e-40 137.7 0.8 2.2e-40 137.7 0.6 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EEQ32751.1 - 1.7e-16 60.4 0.1 3.7e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3445 PF11927.3 EEQ32754.1 - 3.5e-61 206.7 0.0 4.4e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Mid2 PF04478.7 EEQ32755.1 - 9.1e-05 21.9 0.2 0.00024 20.5 0.1 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4366 PF14283.1 EEQ32755.1 - 0.0024 17.3 0.0 0.016 14.5 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) EphA2_TM PF14575.1 EEQ32755.1 - 0.047 14.0 0.0 0.6 10.5 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF605 PF04652.11 EEQ32755.1 - 1.4 8.1 41.4 2.4 7.4 28.7 1.3 1 0 0 1 1 1 0 Vta1 like peroxidase PF00141.18 EEQ32756.1 - 6.6e-51 173.0 0.0 1e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4366 PF14283.1 EEQ32756.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ERG2_Sigma1R PF04622.7 EEQ32757.1 - 2.2e-62 210.1 0.4 2.5e-62 209.9 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein zf-CSL PF05207.8 EEQ32758.1 - 1.6e-15 56.3 0.2 2.3e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EEQ32758.1 - 9.4e-15 54.1 0.1 1.6e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain PITH PF06201.8 EEQ32759.1 - 1.5e-38 131.9 0.0 2.5e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EEQ32759.1 - 1.1e-10 41.1 0.1 2.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EEQ32759.1 - 0.001 17.8 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.1 EEQ32759.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain zf-C2H2 PF00096.21 EEQ32762.1 - 4.3e-12 45.6 13.3 1.2e-06 28.4 0.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ32762.1 - 3.2e-09 36.4 11.0 0.00031 20.8 3.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ32762.1 - 2e-06 27.7 4.7 0.0028 17.7 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EEQ32762.1 - 3.4e-06 27.0 14.4 7.9e-06 25.9 2.6 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 EEQ32762.1 - 0.0017 18.5 11.0 0.0039 17.3 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEQ32762.1 - 0.0034 17.2 0.6 0.0034 17.2 0.4 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger zf-LYAR PF08790.6 EEQ32762.1 - 0.96 9.2 3.2 2.4 7.9 0.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-trcl PF13451.1 EEQ32762.1 - 1.1 8.9 4.3 0.61 9.7 0.5 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain ATP_bind_4 PF01902.12 EEQ32763.1 - 6.6e-19 68.1 0.0 7.3e-05 22.2 0.0 4.1 3 1 1 4 4 4 4 ATP-binding region Ribonuc_L-PSP PF01042.16 EEQ32763.1 - 2.1e-09 37.1 0.0 7.6e-05 22.4 0.0 3.3 3 0 0 3 3 3 2 Endoribonuclease L-PSP Pkinase PF00069.20 EEQ32764.1 - 2.9e-11 43.0 0.0 4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32764.1 - 8e-10 38.2 0.0 2.6e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EEQ32764.1 - 4.3e-08 33.1 2.9 0.00014 21.6 0.6 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EEQ32764.1 - 0.0041 16.2 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEQ32764.1 - 0.015 14.8 0.2 0.24 10.9 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase CTP_transf_1 PF01148.15 EEQ32765.1 - 7.8e-06 25.7 13.4 7.8e-06 25.7 9.3 3.4 4 1 0 4 4 4 1 Cytidylyltransferase family zf-DHHC PF01529.15 EEQ32765.1 - 0.12 11.7 0.9 0.39 10.1 0.6 1.8 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3543 PF12063.3 EEQ32766.1 - 5.2e-93 310.6 0.4 8.4e-93 309.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EEQ32766.1 - 1.1e-63 214.8 0.0 4.9e-63 212.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32766.1 - 6.8e-42 143.3 0.0 2e-41 141.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ32766.1 - 0.017 14.0 0.0 1.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Kinase-like PAZ PF02170.17 EEQ32766.1 - 0.039 13.2 0.1 0.079 12.2 0.0 1.5 1 0 0 1 1 1 0 PAZ domain APH PF01636.18 EEQ32766.1 - 0.072 12.8 0.1 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family NSs PF11073.3 EEQ32766.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like AA_permease_2 PF13520.1 EEQ32767.1 - 1.5e-89 300.4 32.3 1.8e-89 300.1 22.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ32767.1 - 6.7e-19 67.5 30.4 9.5e-19 67.0 21.1 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M1 PF01433.15 EEQ32768.1 - 2.4e-141 471.3 2.5 3.3e-141 470.9 1.7 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EEQ32768.1 - 2.4e-91 306.3 0.3 1.6e-90 303.6 0.0 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EEQ32768.1 - 4.7e-20 71.9 0.5 8.6e-20 71.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF807 PF05660.6 EEQ32768.1 - 0.062 12.9 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Coxiella burnetii protein of unknown function (DUF807) DEAD PF00270.24 EEQ32769.1 - 2.4e-40 137.8 0.0 1.9e-39 134.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ32769.1 - 2.7e-14 52.7 2.1 8.7e-11 41.5 0.0 2.7 1 1 1 2 2 2 2 Helicase conserved C-terminal domain PRAI PF00697.17 EEQ32769.1 - 0.046 13.2 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2984 PF11203.3 EEQ32769.1 - 0.12 12.4 2.1 0.21 11.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) DUF2986 PF11661.3 EEQ32769.1 - 0.59 10.5 9.6 0.1 12.9 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) p450 PF00067.17 EEQ32771.1 - 1.1e-21 76.8 0.1 2.8e-21 75.6 0.0 1.7 1 1 1 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.18 EEQ32772.1 - 2e-09 37.0 0.2 9.3e-08 31.6 0.1 3.0 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.7 EEQ32772.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like TPR_14 PF13428.1 EEQ32773.1 - 0.00093 19.6 4.7 2.3 9.0 0.0 6.0 5 2 2 7 7 7 1 Tetratricopeptide repeat FAT PF02259.18 EEQ32773.1 - 0.0025 16.8 0.2 0.018 14.0 0.0 2.2 2 0 0 2 2 2 1 FAT domain TPR_19 PF14559.1 EEQ32773.1 - 0.025 14.9 0.2 47 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Fe_hyd_SSU PF02256.12 EEQ32773.1 - 0.21 11.6 0.8 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Iron hydrogenase small subunit Aminotran_5 PF00266.14 EEQ32775.1 - 1.7e-25 89.5 0.0 2.6e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EEQ32775.1 - 1.9e-18 66.2 0.0 3.8e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EEQ32775.1 - 2.8e-18 65.6 0.0 5.7e-17 61.4 0.0 2.4 2 0 0 2 2 2 1 MOSC domain Kei1 PF08552.6 EEQ32776.1 - 0.0066 16.1 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 MARVEL PF01284.18 EEQ32776.1 - 0.0068 16.2 9.7 0.0089 15.8 6.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4282 PF14110.1 EEQ32776.1 - 0.058 13.5 4.2 1.8 8.8 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF106 PF01956.11 EEQ32776.1 - 0.3 10.5 2.9 6 6.3 0.0 2.4 2 1 0 2 2 2 0 Integral membrane protein DUF106 DUF3413 PF11893.3 EEQ32776.1 - 0.33 9.7 3.3 0.29 9.9 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) RR_TM4-6 PF06459.7 EEQ32777.1 - 0.082 12.7 1.8 0.081 12.8 1.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GcrA PF07750.6 EEQ32777.1 - 0.09 12.9 2.2 0.11 12.6 1.5 1.1 1 0 0 1 1 1 0 GcrA cell cycle regulator PAP2 PF01569.16 EEQ32778.1 - 1.6e-26 92.4 0.9 2.5e-26 91.8 0.1 1.7 2 0 0 2 2 2 1 PAP2 superfamily But2 PF09792.4 EEQ32780.1 - 9e-52 174.6 0.3 1.2e-51 174.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain NGP1NT PF08153.7 EEQ32782.1 - 5.3e-49 165.4 0.1 8.2e-49 164.8 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EEQ32782.1 - 1.1e-17 64.0 0.0 2e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ32782.1 - 4e-05 22.9 0.0 0.00012 21.3 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EEQ32782.1 - 0.0016 17.6 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EEQ32782.1 - 0.0033 17.2 0.4 0.3 10.8 0.0 3.5 3 1 1 4 4 4 1 Dynamin family Arf PF00025.16 EEQ32782.1 - 0.0093 15.2 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family SusD-like_3 PF14322.1 EEQ32782.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Grp1_Fun34_YaaH PF01184.14 EEQ32783.1 - 1.7e-53 181.0 8.4 2.4e-53 180.5 5.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF202 PF02656.10 EEQ32783.1 - 0.68 10.1 11.0 4.6 7.5 0.3 3.5 1 1 0 2 2 2 0 Domain of unknown function (DUF202) Methyltransf_23 PF13489.1 EEQ32784.1 - 1.7e-22 79.8 0.0 2.6e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ32784.1 - 3.1e-10 40.5 0.0 3.2e-09 37.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ32784.1 - 2.6e-07 31.0 0.0 1.7e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ32784.1 - 6.3e-07 29.0 0.0 4.4e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ32784.1 - 6.8e-06 26.4 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ32784.1 - 0.00045 19.7 0.0 0.00085 18.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 EEQ32784.1 - 0.005 15.9 0.0 0.096 11.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EEQ32784.1 - 0.0077 15.6 0.0 0.019 14.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EEQ32784.1 - 0.023 13.9 0.0 0.092 11.9 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_25 PF13649.1 EEQ32784.1 - 0.047 14.0 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 EEQ32785.1 - 1.2e-67 228.4 0.0 1.5e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEQ32786.1 - 3.3e-44 151.1 0.0 4.1e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Docking PF08990.6 EEQ32786.1 - 1.1 8.6 3.7 1.3 8.3 0.2 2.3 2 0 0 2 2 2 0 Erythronolide synthase docking Pkinase PF00069.20 EEQ32787.1 - 3.5e-40 137.7 0.0 1.6e-39 135.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32787.1 - 4e-28 98.1 0.0 5.7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ32787.1 - 0.0049 15.8 0.0 0.067 12.1 0.0 2.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EEQ32787.1 - 0.0055 16.4 0.2 0.024 14.4 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ32787.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EEQ32787.1 - 0.39 9.4 0.0 0.59 8.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Prefoldin_3 PF13758.1 EEQ32788.1 - 6.2e-34 115.7 1.6 1e-33 115.0 0.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 EEQ32788.1 - 3.5e-23 82.3 0.3 3.5e-23 82.3 0.2 4.2 5 0 0 5 5 5 2 Domain of unknown function (DUF3835) Zip PF02535.17 EEQ32789.1 - 1.5e-33 116.1 16.0 1.5e-33 116.1 11.1 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter MAT1 PF06391.8 EEQ32790.1 - 1.8e-37 128.8 17.1 2.4e-37 128.4 11.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EEQ32790.1 - 0.00016 21.2 4.0 0.00044 19.8 2.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ32790.1 - 0.00036 20.1 5.2 0.0007 19.2 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ32790.1 - 0.0038 17.2 5.6 0.0084 16.1 3.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ32790.1 - 0.013 15.2 7.7 0.083 12.6 5.6 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 EEQ32790.1 - 0.016 14.7 5.2 0.085 12.4 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EEQ32790.1 - 0.017 14.9 5.9 0.033 14.0 4.1 1.5 1 0 0 1 1 1 0 Ring finger domain IncA PF04156.9 EEQ32791.1 - 0.0054 16.3 1.2 0.0091 15.6 0.8 1.3 1 0 0 1 1 1 1 IncA protein Mod_r PF07200.8 EEQ32791.1 - 0.027 14.3 0.4 0.075 12.9 0.3 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Shugoshin_N PF07558.6 EEQ32791.1 - 0.094 12.4 0.2 0.34 10.6 0.1 2.1 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Rab5-bind PF09311.6 EEQ32791.1 - 0.16 11.8 3.3 0.3 10.9 1.2 2.0 1 1 1 2 2 2 0 Rabaptin-like protein DDE_Tnp_IS1 PF03400.8 EEQ32791.1 - 0.28 11.2 0.0 0.57 10.2 0.0 1.4 1 0 0 1 1 1 0 IS1 transposase bZIP_1 PF00170.16 EEQ32791.1 - 3.2 7.7 5.7 8.3 6.4 0.0 2.9 2 1 1 3 3 3 0 bZIP transcription factor DUF765 PF05570.6 EEQ32791.1 - 5.1 7.1 16.5 3.7 7.5 2.4 3.5 2 1 0 2 2 2 0 Circovirus protein of unknown function (DUF765) adh_short PF00106.20 EEQ32792.1 - 3.1e-13 50.0 0.0 4.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ32792.1 - 0.0024 17.5 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEQ32792.1 - 0.0045 17.0 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EEQ32792.1 - 0.039 13.1 0.0 0.26 10.3 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ldh_1_N PF00056.18 EEQ32792.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain PEX11 PF05648.9 EEQ32794.1 - 2.2e-24 85.9 0.2 2.6e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FA_desaturase PF00487.19 EEQ32794.1 - 0.0076 15.7 0.0 0.013 14.9 0.0 1.3 1 1 0 1 1 1 1 Fatty acid desaturase DUF4131 PF13567.1 EEQ32794.1 - 0.02 14.3 2.3 0.023 14.1 0.1 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) ABC2_membrane_2 PF12679.2 EEQ32794.1 - 0.055 12.3 0.7 0.083 11.7 0.1 1.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Flavodoxin_1 PF00258.20 EEQ32795.1 - 9.4e-10 38.6 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EEQ32795.1 - 4.3e-09 36.0 0.0 6.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EEQ32795.1 - 4e-08 33.0 0.0 6.9e-08 32.2 0.0 1.4 2 0 0 2 2 2 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EEQ32795.1 - 0.00096 19.1 0.0 0.0036 17.3 0.0 1.9 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_4 PF12682.2 EEQ32795.1 - 0.0043 16.4 0.4 0.025 13.9 0.3 2.0 1 1 0 1 1 1 1 Flavodoxin Bacteriocin_IIc PF10439.4 EEQ32795.1 - 4.6 7.4 7.0 8.4 6.6 1.9 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide NPL4 PF05021.10 EEQ32796.1 - 2.2e-129 431.0 0.0 2.8e-129 430.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EEQ32796.1 - 1.4e-69 232.3 0.1 2.2e-69 231.7 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EEQ32796.1 - 0.004 17.4 0.0 0.017 15.4 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Kinesin PF00225.18 EEQ32797.1 - 7.5e-116 386.4 0.1 1.2e-115 385.8 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain TSC22 PF01166.13 EEQ32797.1 - 0.56 10.2 4.2 0.18 11.8 0.4 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Topoisom_bac PF01131.15 EEQ32798.1 - 2.7e-74 250.4 0.0 1.5e-67 228.1 0.0 3.0 2 1 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EEQ32798.1 - 1.9e-09 37.3 0.0 4.2e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF3431 PF11913.3 EEQ32800.1 - 3.5e-89 298.0 0.4 4.2e-89 297.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Gly-zipper_Omp PF13488.1 EEQ32801.1 - 0.0049 16.4 2.7 0.0079 15.8 1.9 1.3 1 0 0 1 1 1 1 Glycine zipper Herpes_gE PF02480.11 EEQ32801.1 - 0.008 14.4 0.0 0.0091 14.3 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Gemini_mov PF01708.11 EEQ32801.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein Tim17 PF02466.14 EEQ32802.1 - 0.00021 21.3 5.2 0.00048 20.1 3.6 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family cNMP_binding PF00027.24 EEQ32804.1 - 3.8e-36 122.7 0.0 3.5e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EEQ32804.1 - 2.6e-16 57.8 3.4 0.068 13.2 0.0 9.3 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.28 EEQ32804.1 - 1.1e-06 27.8 9.9 7.8 6.9 0.0 8.9 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 EEQ32804.1 - 5.3e-06 26.1 0.9 0.016 14.9 0.4 4.9 4 1 1 5 5 5 1 Leucine rich repeat F-box-like PF12937.2 EEQ32804.1 - 9.2e-06 25.2 0.7 9.2e-06 25.2 0.5 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EEQ32804.1 - 8.3e-05 22.1 1.3 8.3e-05 22.1 0.9 3.9 4 0 0 4 4 4 1 F-box domain LRR_4 PF12799.2 EEQ32804.1 - 0.0018 17.8 1.1 0.59 9.8 0.0 4.6 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EEQ32804.1 - 0.038 14.1 16.6 43 4.9 0.0 8.2 8 0 0 8 8 8 0 Leucine rich repeat Ste50p-SAM PF09235.5 EEQ32804.1 - 0.066 13.2 3.5 7.7 6.6 0.4 4.2 4 1 0 4 4 4 0 Ste50p, sterile alpha motif Cupin_3 PF05899.7 EEQ32804.1 - 0.2 11.0 0.0 5.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Zn_clus PF00172.13 EEQ32805.1 - 6.7e-08 32.3 7.7 1.1e-07 31.6 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 EEQ32805.1 - 0.00035 20.2 0.4 0.00085 18.9 0.2 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper RasGAP_C PF03836.10 EEQ32805.1 - 0.0033 17.1 0.1 0.0073 16.0 0.1 1.6 1 0 0 1 1 1 1 RasGAP C-terminus DUF2205 PF10224.4 EEQ32805.1 - 0.0038 16.7 0.2 0.014 14.9 0.2 1.9 1 1 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EEQ32805.1 - 0.015 15.5 0.2 0.047 14.0 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF1875 PF08961.5 EEQ32805.1 - 0.018 14.3 0.1 0.018 14.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) DUF904 PF06005.7 EEQ32805.1 - 0.036 14.3 0.8 0.11 12.8 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EEQ32805.1 - 0.32 10.4 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator Slx4 PF09494.5 EEQ32806.1 - 1.5e-26 91.8 0.3 2.7e-26 91.0 0.2 1.4 1 0 0 1 1 1 1 Slx4 endonuclease CGI-121 PF08617.5 EEQ32807.1 - 1.3e-54 184.2 0.7 1.6e-54 183.9 0.5 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.15 EEQ32808.1 - 1.1e-29 103.5 11.7 1.1e-29 103.5 8.1 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 DUF2537 PF10801.3 EEQ32808.1 - 0.14 12.2 5.3 4.7 7.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Cutinase PF01083.17 EEQ32810.1 - 7.9e-37 126.7 0.0 1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.11 EEQ32810.1 - 3.6e-05 23.2 0.0 0.0017 17.8 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEQ32810.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ32810.1 - 0.0013 18.3 0.0 0.0041 16.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold LIP PF03583.9 EEQ32810.1 - 0.0014 17.9 0.1 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EEQ32810.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EEQ32810.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain RRM_1 PF00076.17 EEQ32811.1 - 2.1e-15 56.0 0.0 3.1e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ32811.1 - 6.3e-12 45.3 0.0 9.2e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ32811.1 - 1.5e-10 40.7 0.0 2.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.9 EEQ32812.1 - 2.5e-21 76.4 4.1 4.9e-15 55.7 0.1 3.1 3 1 1 4 4 4 2 Glycosyl hydrolase family 76 DUF2205 PF10224.4 EEQ32815.1 - 1.8e-27 94.6 0.5 2.9e-27 94.0 0.4 1.3 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 EEQ32815.1 - 0.0012 17.2 8.0 0.0014 17.0 5.6 1.0 1 0 0 1 1 1 1 Transmembrane protein Myosin_tail_1 PF01576.14 EEQ32815.1 - 0.0035 15.1 1.7 0.0046 14.7 1.2 1.1 1 0 0 1 1 1 1 Myosin tail Tektin PF03148.9 EEQ32815.1 - 0.0078 14.8 0.6 0.012 14.2 0.4 1.2 1 0 0 1 1 1 1 Tektin family DUF4140 PF13600.1 EEQ32815.1 - 0.0099 16.3 0.7 0.019 15.3 0.5 1.5 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EEQ32815.1 - 0.011 16.1 1.1 0.02 15.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 EEQ32815.1 - 0.014 14.8 0.8 0.02 14.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Prefoldin PF02996.12 EEQ32815.1 - 0.026 14.1 0.6 0.068 12.8 0.2 1.6 1 1 0 1 1 1 0 Prefoldin subunit DivIC PF04977.10 EEQ32815.1 - 0.026 13.9 0.6 0.041 13.3 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator Spectrin PF00435.16 EEQ32815.1 - 0.031 14.5 0.3 0.047 13.9 0.2 1.3 1 0 0 1 1 1 0 Spectrin repeat DUF812 PF05667.6 EEQ32815.1 - 0.07 11.6 3.3 0.072 11.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 EEQ32815.1 - 0.17 9.7 0.5 0.2 9.4 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 EEQ32815.1 - 0.31 10.7 2.7 1.6 8.5 0.1 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper TFIIA PF03153.8 EEQ32815.1 - 0.53 10.1 7.2 0.63 9.8 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CASP_C PF08172.7 EEQ32815.1 - 0.76 8.7 10.3 0.028 13.4 0.8 2.1 2 0 0 2 2 2 0 CASP C terminal Tmemb_cc2 PF10267.4 EEQ32815.1 - 1.9 6.9 8.0 4.1 5.8 5.5 1.7 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein 14-3-3 PF00244.15 EEQ32816.1 - 8.3e-115 381.8 6.8 1e-114 381.5 4.7 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EEQ32816.1 - 0.017 14.6 2.8 0.95 8.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF3461 PF11944.3 EEQ32816.1 - 0.05 13.4 1.7 0.52 10.1 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) IATP PF04568.7 EEQ32817.1 - 7.4e-21 74.0 0.1 8.5e-21 73.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP 2Fe-2S_Ferredox PF11591.3 EEQ32817.1 - 0.062 12.9 2.3 0.1 12.2 1.6 1.3 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide Nsp1_C PF05064.8 EEQ32818.1 - 8.7e-30 102.7 4.9 8.7e-30 102.7 3.4 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EEQ32818.1 - 4e-11 43.1 138.1 0.00013 22.1 30.4 4.6 1 1 3 4 4 4 3 Nucleoporin FG repeat region Spc7 PF08317.6 EEQ32818.1 - 0.006 15.2 8.7 0.26 9.9 1.1 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein APG6 PF04111.7 EEQ32818.1 - 0.012 14.7 6.4 0.024 13.7 4.5 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 ATG16 PF08614.6 EEQ32818.1 - 0.028 14.2 8.5 0.023 14.5 1.6 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ParB PF08775.5 EEQ32818.1 - 0.046 14.0 0.2 0.046 14.0 0.1 2.0 2 0 0 2 2 2 0 ParB family DUF4407 PF14362.1 EEQ32818.1 - 0.093 11.6 6.0 0.15 11.0 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.2 EEQ32818.1 - 0.13 12.0 8.0 0.051 13.4 3.5 1.6 1 1 0 1 1 1 0 Tropomyosin like ArsC PF03960.10 EEQ32818.1 - 0.17 11.9 5.3 11 6.0 0.1 3.1 1 1 2 3 3 3 0 ArsC family Baculo_PEP_C PF04513.7 EEQ32818.1 - 0.39 10.5 6.0 1.2 8.9 4.2 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 EEQ32818.1 - 0.41 10.5 3.7 5.2 7.0 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.1 EEQ32818.1 - 0.6 10.0 10.6 0.036 14.0 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 EEQ32818.1 - 0.6 8.4 8.5 1.7 7.0 5.9 1.5 1 1 0 1 1 1 0 AAA domain DUF342 PF03961.8 EEQ32818.1 - 0.85 7.9 4.6 1.1 7.5 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Macoilin PF09726.4 EEQ32818.1 - 1.1 7.5 6.0 1.5 6.9 4.2 1.4 1 0 0 1 1 1 0 Transmembrane protein Syntaxin PF00804.20 EEQ32818.1 - 1.5 9.0 6.1 38 4.5 4.2 2.3 1 1 0 1 1 1 0 Syntaxin V-SNARE PF05008.10 EEQ32818.1 - 1.9 8.7 6.9 0.83 9.8 0.5 2.9 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus MCPsignal PF00015.16 EEQ32818.1 - 2.8 7.4 8.6 3.9 6.9 3.4 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MscS_porin PF12795.2 EEQ32818.1 - 2.8 7.1 17.9 0.23 10.7 4.8 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain EzrA PF06160.7 EEQ32818.1 - 3 5.9 10.6 5.4 5.0 0.6 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA CENP-Q PF13094.1 EEQ32818.1 - 4 7.4 10.8 7.6 6.5 6.8 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.14 EEQ32818.1 - 4.9 4.8 5.7 3.8 5.2 2.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 EEQ32818.1 - 8.7 6.1 11.5 5.1 6.8 1.7 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF4543 PF15076.1 EEQ32819.1 - 0.015 15.2 0.0 0.047 13.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) zf-MIZ PF02891.15 EEQ32820.1 - 5.9e-11 41.7 0.2 1.3e-10 40.5 0.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SH3_1 PF00018.23 EEQ32822.1 - 1.5e-09 37.0 0.0 3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EEQ32822.1 - 2.9e-09 37.0 0.0 1e-08 35.3 0.0 2.0 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 EEQ32822.1 - 4e-09 35.9 0.1 8.2e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EEQ32822.1 - 1.5e-08 34.3 0.1 2.9e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EEQ32822.1 - 9e-07 29.1 0.1 3e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.12 EEQ32822.1 - 0.00012 21.5 0.1 0.00023 20.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EEQ32822.1 - 0.0019 18.3 0.1 0.0035 17.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Gastrin PF00918.12 EEQ32822.1 - 0.017 15.9 0.1 0.1 13.4 0.1 2.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family PH_8 PF15409.1 EEQ32822.1 - 0.043 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Metallophos PF00149.23 EEQ32823.1 - 1.7e-12 47.2 1.9 2.9e-12 46.3 1.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L14 PF00238.14 EEQ32824.1 - 4.2e-33 113.7 0.0 4.7e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 EEQ32825.1 - 7.5e-74 248.8 0.0 1.2e-73 248.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 EEQ32826.1 - 1.4e-35 121.4 0.0 3.4e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEQ32826.1 - 7.5e-28 96.9 1.8 1.7e-27 95.8 1.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EEQ32826.1 - 2.4e-08 33.5 0.0 9.4e-08 31.5 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Swi5 PF07061.6 EEQ32826.1 - 0.029 14.1 0.8 0.079 12.7 0.3 2.0 2 1 0 2 2 2 0 Swi5 UCR_14kD PF02271.11 EEQ32826.1 - 0.034 13.9 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF3760 PF12586.3 EEQ32827.1 - 0.16 11.8 3.5 5.5 6.9 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) NIF PF03031.13 EEQ32828.1 - 2.8e-39 134.3 0.0 4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EEQ32828.1 - 0.073 13.2 0.3 0.25 11.5 0.0 2.0 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Beta_elim_lyase PF01212.16 EEQ32829.1 - 5.6e-56 189.8 0.0 7.5e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EEQ32829.1 - 0.032 12.5 0.0 0.048 11.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.13 EEQ32830.1 - 4.5e-20 71.6 0.1 3.3e-19 68.7 0.0 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ32830.1 - 1.9e-06 27.6 6.3 3.9e-06 26.6 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EEQ32831.1 - 1.9e-05 24.2 1.2 4e-05 23.2 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ32831.1 - 0.00031 20.2 0.9 0.0007 19.1 0.6 1.6 1 0 0 1 1 1 1 F-box domain Rotavirus_VP1 PF12289.3 EEQ32831.1 - 0.11 12.1 0.1 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Rotavirus VP1 structural protein DUF1399 PF07173.7 EEQ32832.1 - 7.6e-19 68.3 0.8 3e-15 56.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Fungal_trans PF04082.13 EEQ32833.1 - 2.1e-12 46.4 0.7 4.2e-12 45.5 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EEQ32835.1 - 8.2e-72 241.4 0.0 1.2e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32835.1 - 2.4e-38 131.6 0.0 5.9e-38 130.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ32835.1 - 0.00095 18.2 0.2 0.53 9.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.6 EEQ32835.1 - 0.025 13.3 0.1 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 EEQ32836.1 - 6.6e-30 104.0 32.3 9.2e-19 67.3 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ32836.1 - 5.9e-24 84.4 13.2 1.4e-23 83.2 9.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ32838.1 - 1.1e-29 103.2 58.9 9.6e-29 100.1 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ32838.1 - 2.1e-12 46.4 37.9 2.4e-08 32.9 10.3 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EEQ32838.1 - 0.015 15.1 0.2 0.015 15.1 0.1 2.1 2 0 0 2 2 2 0 MFS_1 like family zf-ISL3 PF14690.1 EEQ32839.1 - 0.15 12.0 2.3 7.2 6.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 RecR PF02132.10 EEQ32839.1 - 2.8 7.4 4.6 11 5.5 0.3 2.3 2 0 0 2 2 2 0 RecR protein HAMP PF00672.20 EEQ32840.1 - 8.1e-44 147.6 16.9 1.4e-09 37.9 0.4 6.8 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EEQ32840.1 - 9.5e-31 105.7 0.2 4.7e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEQ32840.1 - 1.1e-26 93.0 1.0 3.3e-24 85.0 0.2 3.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EEQ32840.1 - 4.9e-17 61.6 5.8 2.9e-16 59.2 0.0 4.5 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain NOD PF06816.8 EEQ32840.1 - 0.029 13.4 0.1 0.85 8.7 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein Vps52 PF04129.7 EEQ32840.1 - 0.03 12.8 3.8 3.1 6.1 0.1 3.8 4 0 0 4 4 4 0 Vps52 / Sac2 family Pox_A_type_inc PF04508.7 EEQ32840.1 - 0.054 13.3 0.9 0.78 9.6 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Gp-FAR-1 PF05823.7 EEQ32840.1 - 0.076 12.9 3.9 4.1 7.3 0.0 4.1 3 2 1 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) NAAA-beta PF15508.1 EEQ32840.1 - 0.091 13.1 4.8 9.7 6.6 0.1 5.8 5 3 1 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAA_13 PF13166.1 EEQ32840.1 - 0.17 10.3 25.0 0.62 8.4 0.8 4.1 1 1 2 4 4 4 0 AAA domain DUF948 PF06103.6 EEQ32840.1 - 1.2 9.0 33.4 7.5 6.4 0.6 7.9 4 3 4 8 8 8 0 Bacterial protein of unknown function (DUF948) tRNA-synt_2d PF01409.15 EEQ32841.1 - 3e-88 295.2 0.0 3.9e-88 294.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EEQ32841.1 - 6.1e-06 25.2 0.5 0.00032 19.5 0.0 3.0 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EEQ32841.1 - 0.00059 19.4 0.0 0.0051 16.4 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_S21e PF01249.13 EEQ32842.1 - 2.9e-41 139.3 0.0 3.2e-41 139.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.23 EEQ32843.1 - 7.6e-14 51.5 0.0 7.4e-13 48.3 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.20 EEQ32844.1 - 1.6e-133 445.0 4.1 1.9e-133 444.7 2.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EEQ32844.1 - 3.1e-20 71.6 0.1 8.2e-10 38.3 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EEQ32844.1 - 1.1e-07 31.0 1.1 2.5e-07 29.8 0.7 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EEQ32844.1 - 3.8e-06 26.2 12.1 0.0033 16.6 6.2 2.6 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 EEQ32844.1 - 2.3e-05 23.8 1.3 4.5e-05 22.8 0.9 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.16 EEQ32844.1 - 0.0022 16.6 0.0 0.0047 15.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain EAL PF00563.15 EEQ32844.1 - 0.0036 16.8 0.2 0.59 9.5 0.0 2.3 2 0 0 2 2 2 2 EAL domain Aldolase PF01081.14 EEQ32844.1 - 0.025 13.7 1.7 0.11 11.6 0.2 2.4 2 0 0 2 2 2 0 KDPG and KHG aldolase ThiG PF05690.9 EEQ32844.1 - 0.032 13.3 0.5 0.032 13.3 0.3 1.8 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Pkinase PF00069.20 EEQ32845.1 - 0.047 12.8 0.1 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RasGAP_C PF03836.10 EEQ32846.1 - 4.6e-48 162.5 5.7 1.4e-47 160.9 4.0 1.9 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EEQ32846.1 - 3.2e-42 144.4 0.0 9.2e-42 142.9 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EEQ32846.1 - 3.4e-12 46.3 0.0 1.3e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.22 EEQ32846.1 - 2.6e-09 35.8 41.7 0.48 10.2 0.0 14.9 17 0 0 17 17 17 5 IQ calmodulin-binding motif ENTH PF01417.15 EEQ32847.1 - 4.1e-45 152.6 0.1 7.3e-45 151.8 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EEQ32847.1 - 0.0043 15.8 0.0 0.0068 15.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain SH3_1 PF00018.23 EEQ32848.1 - 4.7e-11 41.9 0.0 8.7e-11 41.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ32848.1 - 1.4e-10 40.5 0.0 2.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ32848.1 - 1.6e-07 30.7 0.0 2.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 EEQ32849.1 - 1.8e-23 82.8 50.1 6.7e-13 48.0 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEQ32849.1 - 6.6e-10 37.9 13.4 6.6e-10 37.9 9.3 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein 7TM_GPCR_Srh PF10318.4 EEQ32849.1 - 2.2e-05 23.4 0.9 2.2e-05 23.4 0.6 2.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh MFS_1_like PF12832.2 EEQ32849.1 - 0.38 10.5 14.4 0.95 9.3 1.3 3.4 4 0 0 4 4 4 0 MFS_1 like family DUF4011 PF13195.1 EEQ32851.1 - 0.063 13.3 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) HMG-CoA_red PF00368.13 EEQ32852.1 - 1.4e-153 511.0 9.3 1.8e-153 510.6 6.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EEQ32852.1 - 3.1e-47 160.1 0.0 6.2e-47 159.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EEQ32852.1 - 2.3e-11 43.3 6.7 3.3e-10 39.6 4.7 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EEQ32852.1 - 2.7e-05 22.3 1.0 2.7e-05 22.3 0.7 1.3 2 0 0 2 2 2 1 Patched family CVNH PF08881.5 EEQ32853.1 - 1.3e-26 92.7 0.1 1.5e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 CVNH domain GIT_SHD PF08518.6 EEQ32854.1 - 2.4e-22 77.9 6.7 8.2e-13 47.4 0.6 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT APG6 PF04111.7 EEQ32854.1 - 0.005 15.9 7.1 0.005 15.9 4.9 2.6 1 1 1 2 2 2 1 Autophagy protein Apg6 Rhabdo_glycop PF00974.13 EEQ32854.1 - 0.016 13.4 0.2 0.026 12.7 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Xylo_C PF12529.3 EEQ32854.1 - 0.088 12.1 5.2 0.19 11.1 3.6 1.5 1 0 0 1 1 1 0 Xylosyltransferase C terminal TPR_MLP1_2 PF07926.7 EEQ32854.1 - 1.4 8.6 31.8 0.06 13.0 11.1 3.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Viral_P18 PF04521.8 EEQ32854.1 - 9.3 5.7 10.8 9.4 5.7 2.2 3.6 3 1 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Pro_isomerase PF00160.16 EEQ32855.1 - 7.8e-43 146.3 0.2 8.9e-43 146.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_PH PF01138.16 EEQ32856.1 - 3e-34 118.1 0.2 4.4e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 EEQ32856.1 - 0.0048 17.3 4.0 0.0048 17.3 2.8 1.9 2 0 0 2 2 2 1 Coiled coil SNF2_N PF00176.18 EEQ32857.1 - 1.4e-54 184.9 0.0 2.2e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EEQ32857.1 - 6.8e-28 96.3 0.6 1.7e-27 95.1 0.4 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EEQ32857.1 - 7.4e-14 51.3 0.0 2.7e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ32857.1 - 0.00018 21.0 0.0 0.00042 19.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EEQ32857.1 - 0.00042 20.1 0.8 0.0025 17.6 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1215 PF06744.7 EEQ32857.1 - 0.0014 18.2 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1215) HDA2-3 PF11496.3 EEQ32857.1 - 0.028 13.2 0.0 0.052 12.3 0.0 1.5 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Ssu72 PF04722.8 EEQ32858.1 - 1.2e-83 279.3 0.0 1.4e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.6 EEQ32858.1 - 0.85 8.9 9.1 1.4 8.2 6.3 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2946 PF11162.3 EEQ32859.1 - 0.0028 17.8 5.4 0.025 14.8 0.2 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF2946) Trypan_PARP PF05887.6 EEQ32859.1 - 0.44 10.3 9.4 0.039 13.7 2.4 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) EST1 PF10374.4 EEQ32859.1 - 0.99 9.4 5.5 0.91 9.5 2.1 2.3 2 1 0 2 2 2 0 Telomerase activating protein Est1 Acyl-CoA_dh_1 PF00441.19 EEQ32860.1 - 1.8e-18 67.0 0.4 1.6e-17 64.0 0.3 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ32860.1 - 1.9e-05 24.0 0.5 0.00016 21.0 0.3 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Oxysterol_BP PF01237.13 EEQ32861.1 - 3.5e-72 242.8 0.3 7.5e-65 218.7 0.1 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein APH PF01636.18 EEQ32862.1 - 1.9e-06 27.7 0.1 2.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3605 PF12239.3 EEQ32863.1 - 3.8e-60 202.3 2.2 4.7e-60 202.0 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.15 EEQ32864.1 - 1.4e-26 93.4 0.0 2.3e-21 76.5 0.0 2.0 2 0 0 2 2 2 2 Isochorismatase family Hist_deacetyl PF00850.14 EEQ32865.1 - 5.5e-76 255.8 0.2 7.3e-76 255.4 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain BSP_II PF05432.6 EEQ32865.1 - 1 8.5 7.3 1.5 8.0 5.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ING PF12998.2 EEQ32866.1 - 1.4e-23 83.1 4.8 2.4e-23 82.3 3.3 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EEQ32866.1 - 2.2e-08 33.6 9.9 3.9e-08 32.8 6.8 1.5 1 0 0 1 1 1 1 PHD-finger DUF4200 PF13863.1 EEQ32866.1 - 0.35 10.8 3.0 3.8 7.4 2.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TFIIA PF03153.8 EEQ32866.1 - 1.7 8.4 17.9 1.3 8.8 11.6 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpc34 PF05158.7 EEQ32867.1 - 5.4e-107 357.7 0.0 6.6e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit PadR PF03551.9 EEQ32867.1 - 0.084 12.6 0.1 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Rrf2 PF02082.15 EEQ32867.1 - 0.09 12.9 0.1 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator TPR_11 PF13414.1 EEQ32868.1 - 2.5e-52 174.4 24.1 1e-15 57.1 0.6 6.4 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EEQ32868.1 - 4e-39 130.6 21.7 1.7e-05 24.1 0.0 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ32868.1 - 6.5e-31 103.7 21.1 0.00019 21.0 0.1 9.8 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ32868.1 - 3.5e-17 62.0 13.7 1.2e-08 34.7 0.1 5.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ32868.1 - 1.4e-15 57.5 14.3 0.0026 18.4 0.0 6.8 3 3 4 7 7 7 7 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ32868.1 - 3.8e-14 52.7 18.2 0.00071 19.8 0.1 6.4 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ32868.1 - 6.4e-13 48.0 17.0 0.31 11.7 0.2 9.8 5 3 4 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ32868.1 - 9.4e-13 46.9 13.2 0.049 13.4 0.0 7.9 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ32868.1 - 1.3e-10 40.6 10.3 0.019 15.1 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ32868.1 - 9.7e-08 31.7 7.8 0.0071 16.1 0.3 5.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ32868.1 - 2.7e-07 29.8 12.3 0.045 13.5 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 EEQ32868.1 - 0.00014 21.9 13.2 0.05 13.7 0.7 3.8 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Inhibitor_I9 PF05922.11 EEQ32868.1 - 0.0013 19.2 0.6 0.0062 17.0 0.0 2.5 3 0 0 3 3 1 1 Peptidase inhibitor I9 TPR_6 PF13174.1 EEQ32868.1 - 0.062 13.7 20.5 7 7.3 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EEQ32868.1 - 1.7 7.9 9.6 12 5.2 0.1 5.9 7 0 0 7 7 7 0 SHNi-TPR C2 PF00168.25 EEQ32869.1 - 4e-63 209.2 3.0 3.7e-17 61.9 0.0 5.5 5 0 0 5 5 5 5 C2 domain RRM_1 PF00076.17 EEQ32870.1 - 2.2e-17 62.4 0.0 6.7e-12 44.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ32870.1 - 8.5e-16 57.6 0.0 6.1e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ32870.1 - 2.3e-14 52.9 0.0 4.7e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEQ32870.1 - 0.0017 18.0 0.0 0.19 11.5 0.0 3.2 2 1 0 2 2 2 1 Limkain b1 UDPGP PF01704.13 EEQ32871.1 - 6.7e-181 601.3 0.1 7.8e-181 601.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.8 EEQ32871.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilO zf-CCCH PF00642.19 EEQ32873.1 - 8.1e-09 34.9 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EEQ32873.1 - 5.1e-06 26.2 0.0 9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ32873.1 - 0.00029 20.3 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ32873.1 - 0.043 13.7 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4185 PF13810.1 EEQ32874.1 - 0.00025 20.0 0.2 0.00064 18.7 0.2 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4185) Kelch_6 PF13964.1 EEQ32874.1 - 0.092 12.9 0.1 0.37 11.0 0.0 2.0 1 0 0 1 1 1 0 Kelch motif Amidase PF01425.16 EEQ32875.1 - 1.8e-84 284.1 0.0 3e-84 283.4 0.0 1.3 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.11 EEQ32876.1 - 1.5e-16 60.0 42.6 3.8e-16 58.7 15.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.8 EEQ32877.1 - 1.8e-28 100.0 0.0 2.3e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Epimerase PF01370.16 EEQ32878.1 - 4.4e-06 26.2 0.0 6.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 EEQ32879.1 - 7.2e-06 25.8 12.6 1.2e-05 25.0 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ32879.1 - 0.00022 20.1 0.1 0.00045 19.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FYVE PF01363.16 EEQ32880.1 - 3.9e-19 68.3 6.7 3.9e-19 68.3 4.7 2.9 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EEQ32880.1 - 6.4e-09 35.5 4.8 6.4e-09 35.5 3.3 3.7 4 0 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 EEQ32880.1 - 0.0016 18.4 2.3 0.0016 18.4 1.6 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEQ32880.1 - 0.0025 17.4 2.9 0.0025 17.4 2.0 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ32880.1 - 0.02 14.9 4.1 0.02 14.9 2.8 3.9 4 2 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EEQ32880.1 - 0.054 13.3 0.5 0.054 13.3 0.3 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger RINGv PF12906.2 EEQ32880.1 - 0.13 12.3 8.5 0.23 11.5 3.3 2.8 2 0 0 2 2 2 0 RING-variant domain Elf1 PF05129.8 EEQ32880.1 - 1.2 8.8 5.5 1.1 9.0 1.0 2.7 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like TRP PF06011.7 EEQ32881.1 - 8e-61 205.9 18.4 4e-41 140.9 9.7 3.0 2 1 1 3 3 3 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEQ32881.1 - 3.6e-16 59.4 0.3 5.7e-16 58.8 0.2 1.3 1 0 0 1 1 1 1 ML-like domain Lig_chan PF00060.21 EEQ32881.1 - 1.4 8.5 5.5 3.9 7.1 3.8 1.7 1 0 0 1 1 1 0 Ligand-gated ion channel Strabismus PF06638.6 EEQ32881.1 - 7.7 4.6 6.3 14 3.8 4.4 1.3 1 0 0 1 1 1 0 Strabismus protein Cys_Met_Meta_PP PF01053.15 EEQ32883.1 - 5.5e-63 212.5 0.0 2.4e-62 210.4 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EEQ32883.1 - 0.0012 17.6 0.0 0.0021 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EEQ32883.1 - 0.002 17.1 0.0 0.0083 15.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EEQ32883.1 - 0.0095 15.0 0.0 0.096 11.7 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2073 PF09846.4 EEQ32883.1 - 0.12 11.9 0.0 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) Pkinase PF00069.20 EEQ32884.1 - 1.3e-20 73.6 0.0 2.2e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32884.1 - 2.2e-06 26.9 0.0 3.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ32884.1 - 0.11 11.2 0.2 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EEQ32884.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EEQ32884.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 ThiS PF02597.15 EEQ32885.1 - 0.00016 22.0 0.0 0.0016 18.7 0.0 1.9 1 1 0 1 1 1 1 ThiS family GFA PF04828.9 EEQ32886.1 - 2.5e-20 72.2 1.0 2.5e-20 72.2 0.7 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-Mss51 PF13824.1 EEQ32886.1 - 3.7 7.4 9.1 7.3 6.5 5.0 2.6 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Fungal_trans PF04082.13 EEQ32887.1 - 6.4e-11 41.6 0.1 1.5e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ32887.1 - 9.8e-09 34.9 5.0 1.8e-08 34.1 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 EEQ32888.1 - 8e-26 90.9 0.2 2.2e-25 89.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.19 EEQ32888.1 - 1e-22 80.3 26.3 4.4e-22 78.2 18.2 1.9 1 1 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 EEQ32888.1 - 7.1e-10 39.3 0.1 2.8e-07 30.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEQ32888.1 - 2.4e-05 23.8 0.1 0.00058 19.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EEQ32888.1 - 2.4e-05 23.5 0.1 4.3e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ32888.1 - 7.9e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EEQ32888.1 - 9.9e-05 21.6 0.4 0.00048 19.4 0.0 2.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EEQ32888.1 - 0.0003 19.9 0.0 0.021 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EEQ32888.1 - 0.0008 19.1 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EEQ32888.1 - 0.0019 18.3 0.1 0.014 15.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EEQ32888.1 - 0.003 17.0 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EEQ32888.1 - 0.0041 16.6 0.2 0.083 12.3 0.1 2.4 2 1 1 3 3 3 1 AAA-like domain AAA_29 PF13555.1 EEQ32888.1 - 0.0042 16.5 0.3 0.0096 15.4 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EEQ32888.1 - 0.0048 17.0 0.0 0.069 13.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ32888.1 - 0.0049 17.6 0.0 0.012 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEQ32888.1 - 0.0051 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 EEQ32888.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 EEQ32888.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ32888.1 - 0.019 15.2 0.0 0.058 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEQ32888.1 - 0.021 14.6 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EEQ32888.1 - 0.022 14.6 0.1 0.13 12.1 0.0 2.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.12 EEQ32888.1 - 0.025 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EEQ32888.1 - 0.037 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 EEQ32888.1 - 0.043 12.5 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 EEQ32888.1 - 0.047 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EEQ32888.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 EEQ32888.1 - 0.079 12.5 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EEQ32888.1 - 0.26 11.5 0.9 0.52 10.6 0.1 1.8 2 0 0 2 2 1 0 AAA domain AAA_13 PF13166.1 EEQ32888.1 - 0.74 8.1 5.6 0.4 9.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain tRNA-synt_2 PF00152.15 EEQ32889.1 - 6e-101 337.5 0.0 7.7e-101 337.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ32889.1 - 4.8e-06 26.3 0.0 1.1e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EEQ32889.1 - 0.0042 16.6 0.4 0.015 14.8 0.2 1.8 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) PUD PF03714.9 EEQ32890.1 - 0.25 11.5 2.0 0.4 10.8 1.4 1.5 1 1 0 1 1 1 0 Bacterial pullanase-associated domain PEP_mutase PF13714.1 EEQ32891.1 - 3.5e-65 219.5 0.7 4e-65 219.3 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase AP_endonuc_2 PF01261.19 EEQ32891.1 - 0.014 14.6 0.6 0.36 10.0 0.1 2.2 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Aminotran_MocR PF12897.2 EEQ32891.1 - 0.017 13.7 0.1 0.079 11.5 0.1 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase ABC_tran PF00005.22 EEQ32892.1 - 1.1e-47 161.7 0.0 1.4e-29 103.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ32892.1 - 6.2e-35 120.9 29.4 5.2e-19 68.7 9.7 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EEQ32892.1 - 2.2e-11 43.4 0.0 0.0066 15.6 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEQ32892.1 - 9.8e-06 26.0 0.8 0.00043 20.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ32892.1 - 3.8e-05 23.7 1.8 0.03 14.3 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EEQ32892.1 - 4.7e-05 22.8 1.0 0.073 12.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EEQ32892.1 - 0.00011 21.2 0.0 0.034 13.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 EEQ32892.1 - 0.00014 22.0 0.0 2.1 8.5 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 EEQ32892.1 - 0.00023 20.6 0.1 0.74 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ32892.1 - 0.00057 19.8 0.1 0.4 10.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEQ32892.1 - 0.00073 18.7 0.1 0.9 8.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 EEQ32892.1 - 0.0009 19.2 1.8 8.3 6.2 0.0 4.0 3 1 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EEQ32892.1 - 0.0025 17.2 0.0 3.6 6.9 0.0 3.0 2 1 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 EEQ32892.1 - 0.0034 17.2 1.8 0.81 9.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 EEQ32892.1 - 0.0035 17.8 0.1 5 7.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Zeta_toxin PF06414.7 EEQ32892.1 - 0.02 14.0 0.1 4.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EEQ32892.1 - 0.051 13.0 0.0 10 5.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EEQ32892.1 - 0.058 12.9 0.7 22 4.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.12 EEQ32892.1 - 0.064 12.6 0.0 3.8 6.9 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 EEQ32892.1 - 0.078 11.9 0.1 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EEQ32892.1 - 0.1 11.7 0.3 35 3.5 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein AAA_17 PF13207.1 EEQ32892.1 - 0.19 12.5 0.1 20 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoD PF09423.5 EEQ32893.1 - 1.7e-158 527.9 1.8 1.9e-158 527.7 1.3 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase LigD_N PF13298.1 EEQ32895.1 - 3e-10 40.1 0.0 5.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Sulf_transp PF04143.9 EEQ32896.1 - 6.4e-14 51.6 25.3 3.5e-10 39.7 4.8 4.0 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 EEQ32896.1 - 1.6e-09 37.3 0.7 1.6e-09 37.3 0.5 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4341) Peptidase_M28 PF04389.12 EEQ32897.1 - 1.1e-33 116.4 0.0 1.6e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Rhodanese PF00581.15 EEQ32900.1 - 6.9e-10 39.2 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain HTH_17 PF12728.2 EEQ32900.1 - 0.0017 18.5 0.1 2.3 8.5 0.0 2.8 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.1 EEQ32900.1 - 0.067 12.8 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain MutS_V PF00488.16 EEQ32901.1 - 1.3e-79 266.9 0.0 2.1e-79 266.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEQ32901.1 - 5e-53 179.9 0.0 9.5e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEQ32901.1 - 2.3e-33 114.5 0.1 1.3e-32 112.2 0.1 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EEQ32901.1 - 4.6e-16 58.7 1.5 9.3e-16 57.7 1.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EEQ32901.1 - 6.7e-13 48.8 0.0 2.1e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 EEQ32901.1 - 0.00071 19.9 1.8 0.006 16.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ32901.1 - 0.026 14.0 0.1 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EEQ32901.1 - 0.053 13.4 1.3 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.20 EEQ32902.1 - 4.4e-62 209.8 0.0 1.1e-47 162.5 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) Raffinose_syn PF05691.7 EEQ32903.1 - 1.8e-50 171.2 5.3 9.8e-41 139.1 1.3 3.0 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EEQ32903.1 - 0.016 13.9 0.4 0.041 12.5 0.3 1.6 1 1 0 1 1 1 0 Melibiase Hen1_L PF12623.2 EEQ32903.1 - 0.041 12.6 0.1 1.8 7.2 0.0 2.2 2 0 0 2 2 2 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Aldedh PF00171.17 EEQ32904.1 - 1.3e-158 528.1 0.8 1.6e-158 527.8 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRN9 PF10680.4 EEQ32905.1 - 1.3e-17 63.2 0.1 4.6e-17 61.5 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 EEQ32905.1 - 0.015 15.5 1.5 0.031 14.5 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ32905.1 - 0.15 12.4 0.2 0.48 10.8 0.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pescadillo_N PF06732.6 EEQ32906.1 - 7.2e-115 383.0 0.1 7.2e-115 383.0 0.1 2.4 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EEQ32906.1 - 3.4e-06 27.1 0.0 0.00013 22.0 0.0 3.1 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 EEQ32907.1 - 6.6e-121 403.7 27.2 7.6e-121 403.5 18.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Acetyltransf_1 PF00583.19 EEQ32908.1 - 7.3e-15 54.7 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEQ32908.1 - 9.9e-05 22.0 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EEQ32908.1 - 0.00015 21.8 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEQ32908.1 - 0.00066 19.6 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ32908.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEQ32908.1 - 0.0051 16.9 0.0 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.10 EEQ32909.1 - 1.1e-12 47.5 0.0 2.8e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ32909.1 - 4.6e-12 45.9 0.1 1.1e-11 44.7 0.0 1.6 1 1 0 1 1 1 1 Complex1_LYR-like HIG_1_N PF04588.8 EEQ32910.1 - 2.1e-22 78.6 0.2 3.5e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region OPA3 PF07047.7 EEQ32910.1 - 0.083 12.6 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF2681 PF10883.3 EEQ32910.1 - 0.11 12.6 1.4 0.2 11.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PALP PF00291.20 EEQ32911.1 - 5.3e-65 219.6 1.3 7e-65 219.2 0.9 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EEQ32911.1 - 5.9e-46 153.9 0.0 5.6e-23 80.3 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.13 EEQ32912.1 - 3.9e-20 71.5 9.8 8.1e-20 70.5 6.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 EEQ32912.1 - 0.1 11.9 0.4 0.19 11.0 0.3 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family GTP_EFTU PF00009.22 EEQ32913.1 - 5.3e-56 189.0 0.0 1.1e-55 188.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EEQ32913.1 - 4.1e-32 109.8 0.0 8.4e-32 108.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EEQ32913.1 - 2.1e-30 104.7 0.0 4.3e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEQ32913.1 - 6.8e-24 83.5 0.0 2.1e-23 81.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEQ32913.1 - 1.2e-11 44.5 0.0 4.9e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 EEQ32913.1 - 0.018 14.6 0.1 0.071 12.6 0.0 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF442 PF04273.8 EEQ32913.1 - 0.074 12.9 0.1 2.8 7.8 0.0 2.8 3 0 0 3 3 3 0 Putative phosphatase (DUF442) Abhydrolase_5 PF12695.2 EEQ32914.1 - 6.7e-14 51.8 0.0 1.5e-13 50.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ32914.1 - 8.4e-12 45.4 0.0 1.2e-11 44.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEQ32914.1 - 5.6e-05 22.8 0.0 8.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EEQ32914.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 EEQ32914.1 - 0.002 16.9 0.0 0.0034 16.1 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 EEQ32914.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 1 1 0 1 1 1 0 Putative lysophospholipase DUF3221 PF11518.3 EEQ32914.1 - 0.059 13.0 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) Peptidase_S9 PF00326.16 EEQ32914.1 - 0.14 11.3 0.0 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Gag_p24 PF00607.15 EEQ32915.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) TLD PF07534.11 EEQ32916.1 - 8.7e-18 64.6 0.0 2.2e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 TLD NMT PF01233.14 EEQ32917.1 - 6.4e-77 256.7 0.0 1.2e-76 255.8 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EEQ32917.1 - 9.4e-76 253.4 0.1 1.4e-75 252.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EEQ32917.1 - 1.4e-05 24.9 0.0 3.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEQ32917.1 - 0.0063 16.6 0.0 0.02 15.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain BHD_2 PF10404.4 EEQ32917.1 - 0.082 13.2 0.1 0.38 11.0 0.1 2.1 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 2 Mur_ligase_M PF08245.7 EEQ32918.1 - 3.9e-07 30.3 0.5 5e-06 26.6 0.3 2.5 1 1 0 1 1 1 1 Mur ligase middle domain Syja_N PF02383.13 EEQ32919.1 - 7.3e-91 304.2 0.0 9.2e-91 303.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain adh_short PF00106.20 EEQ32920.1 - 2.7e-12 46.9 0.0 6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ32920.1 - 1.1e-09 38.4 0.0 8.1e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ32920.1 - 2.3e-05 24.1 0.9 0.00012 21.8 0.1 2.2 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EEQ32920.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EEQ32920.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-CCCH PF00642.19 EEQ32921.1 - 2.2e-18 65.4 29.8 9.1e-07 28.4 0.5 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EEQ32921.1 - 0.79 9.2 5.7 2 7.9 0.3 3.2 2 0 0 2 2 2 0 Putative zinc-finger domain CC PF04942.9 EEQ32921.1 - 2.4 8.1 6.1 2.9 7.8 0.0 3.0 3 0 0 3 3 3 0 CC domain Glyco_hydro_18 PF00704.23 EEQ32922.1 - 5.7e-63 213.4 0.0 1.1e-62 212.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.20 EEQ32923.1 - 1.8e-16 60.0 0.0 4.4e-15 55.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32923.1 - 1.6e-05 24.1 0.0 3.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ32923.1 - 0.01 15.5 0.1 0.033 13.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EEQ32923.1 - 0.056 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3712 PF12505.3 EEQ32924.1 - 1.9e-32 111.8 4.0 7.9e-32 109.9 1.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EEQ32924.1 - 0.068 13.5 0.2 0.38 11.1 0.0 2.3 2 1 0 2 2 2 0 Late embryogenesis abundant protein Ion_trans_N PF08412.5 EEQ32924.1 - 0.16 11.3 0.4 0.39 10.0 0.3 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal DUF4307 PF14155.1 EEQ32924.1 - 0.18 11.6 0.2 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF4320 PF14208.1 EEQ32924.1 - 2.2 8.2 4.1 25 4.8 0.4 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4320) Sel1 PF08238.7 EEQ32925.1 - 1.8e-14 53.8 9.9 1.3e-05 25.6 2.4 4.4 4 0 0 4 4 4 3 Sel1 repeat Glyco_hydro_18 PF00704.23 EEQ32926.1 - 6e-22 78.5 0.0 1.5e-20 73.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_11 PF08241.7 EEQ32927.1 - 2e-28 98.7 0.3 5.3e-14 52.4 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ32927.1 - 1.2e-17 63.8 0.1 9.1e-10 38.3 0.0 3.4 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ32927.1 - 7.1e-16 58.3 0.1 5.9e-11 42.3 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ32927.1 - 2.1e-15 56.9 0.1 3.3e-08 33.8 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ32927.1 - 1.3e-14 54.6 0.0 2.6e-09 37.6 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ32927.1 - 2.4e-14 53.5 0.0 2.1e-08 34.5 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ32927.1 - 9.2e-10 38.0 0.0 3.3e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEQ32927.1 - 5e-09 36.1 0.1 3.1e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain MetW PF07021.7 EEQ32927.1 - 1.3e-07 31.2 0.0 0.012 14.9 0.0 2.5 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW CMAS PF02353.15 EEQ32927.1 - 3e-07 29.8 0.0 8.1e-07 28.3 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase TPMT PF05724.6 EEQ32927.1 - 1.5e-05 24.5 0.0 3.6e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 EEQ32927.1 - 6.3e-05 22.2 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.13 EEQ32927.1 - 0.00028 20.2 0.1 0.21 10.8 0.0 2.6 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain PCMT PF01135.14 EEQ32927.1 - 0.00031 20.3 0.0 0.00073 19.1 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0146 PF03686.8 EEQ32927.1 - 0.00056 19.7 0.1 0.003 17.3 0.0 2.3 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0146) FmrO PF07091.6 EEQ32927.1 - 0.0012 17.9 0.0 0.0025 16.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) NodS PF05401.6 EEQ32927.1 - 0.0016 17.8 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.9 EEQ32927.1 - 0.0038 16.6 0.0 0.01 15.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EEQ32927.1 - 0.016 14.5 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_9 PF08003.6 EEQ32927.1 - 0.04 12.6 0.0 4.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) 3HCDH_N PF02737.13 EEQ32927.1 - 0.062 12.9 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PrmA PF06325.8 EEQ32927.1 - 0.099 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Fer4_5 PF12801.2 EEQ32927.1 - 0.19 11.5 0.5 0.45 10.3 0.4 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain EphA2_TM PF14575.1 EEQ32928.1 - 0.021 15.2 1.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4131 PF13567.1 EEQ32928.1 - 0.04 13.3 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Myc_target_1 PF15179.1 EEQ32928.1 - 0.23 11.0 6.0 0.72 9.4 4.2 1.7 1 1 0 1 1 1 0 Myc target protein 1 F-box PF00646.28 EEQ32929.1 - 0.0015 18.1 0.0 0.0015 18.1 0.0 2.9 3 1 0 3 3 3 1 F-box domain F-box-like PF12937.2 EEQ32929.1 - 0.0041 16.8 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EEQ32929.1 - 0.29 10.8 5.1 3.1 7.5 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ32929.1 - 1.6 8.5 6.1 3.6 7.4 0.1 3.1 3 1 0 3 3 3 0 Leucine rich repeat Yip1 PF04893.12 EEQ32930.1 - 0.00012 21.6 19.0 0.0032 16.9 6.4 2.1 2 0 0 2 2 2 2 Yip1 domain PgaD PF13994.1 EEQ32930.1 - 0.013 15.0 2.8 0.013 15.0 1.9 2.8 2 2 1 3 3 3 0 PgaD-like protein 7tm_7 PF08395.7 EEQ32930.1 - 0.04 12.9 20.7 0.09 11.7 14.4 1.4 1 1 0 1 1 1 0 7tm Chemosensory receptor tRNA-synt_1g PF09334.6 EEQ32931.1 - 0.063 11.9 0.0 2.3 6.7 0.0 2.1 1 1 1 2 2 2 0 tRNA synthetases class I (M) DUF1776 PF08643.5 EEQ32932.1 - 5.8e-89 298.1 0.0 7e-89 297.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WLM PF08325.5 EEQ32933.1 - 8.7e-60 201.7 0.0 1.3e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EEQ32933.1 - 0.00077 18.5 3.4 0.00077 18.5 2.4 3.2 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others SprT-like PF10263.4 EEQ32933.1 - 0.00082 19.0 0.5 0.0068 16.0 0.0 2.4 2 0 0 2 2 2 1 SprT-like family DUF45 PF01863.12 EEQ32933.1 - 0.0009 19.0 1.8 0.0022 17.8 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_M54 PF07998.6 EEQ32933.1 - 0.016 14.9 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DUF955 PF06114.8 EEQ32933.1 - 0.083 12.6 0.9 0.17 11.5 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF955) Trp_DMAT PF11991.3 EEQ32934.1 - 2e-106 356.2 0.0 2.3e-106 356.0 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_3 PF01494.14 EEQ32935.1 - 7.8e-14 51.4 1.7 2e-09 36.9 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEQ32935.1 - 3.4e-09 36.0 3.3 0.00012 21.0 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ32935.1 - 1.2e-06 27.6 1.4 1.8e-06 27.0 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EEQ32935.1 - 1.7e-06 28.0 0.5 3.9e-06 26.8 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ32935.1 - 2.9e-06 25.9 0.2 0.00035 19.1 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EEQ32935.1 - 0.00045 20.1 0.5 0.045 13.7 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EEQ32935.1 - 0.0063 15.6 0.2 0.01 14.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EEQ32935.1 - 0.017 14.0 1.9 0.03 13.1 1.3 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EEQ32935.1 - 0.032 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EEQ32935.1 - 0.076 13.4 0.4 23 5.4 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEQ32935.1 - 0.095 11.6 0.0 22 3.8 0.1 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.12 EEQ32935.1 - 0.096 11.7 0.7 0.39 9.7 0.1 1.9 2 0 0 2 2 2 0 Thi4 family AMP-binding PF00501.23 EEQ32937.1 - 9.7e-86 287.7 0.0 1.4e-85 287.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EEQ32937.1 - 1.6e-45 155.2 0.1 4.9e-16 58.4 0.1 6.1 4 1 1 5 5 5 5 Condensation domain PP-binding PF00550.20 EEQ32937.1 - 5.5e-29 100.2 0.5 8.8e-14 51.5 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ32937.1 - 1.7e-05 25.6 0.0 8.5e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribonuclease PF00545.15 EEQ32938.1 - 7.6e-19 67.5 0.3 9.9e-19 67.2 0.2 1.1 1 0 0 1 1 1 1 ribonuclease WD40 PF00400.27 EEQ32939.1 - 1.7e-66 217.8 20.3 1.1e-07 31.4 0.1 11.5 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EEQ32939.1 - 9.7e-22 76.9 0.0 1.6e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EEQ32939.1 - 2.1e-05 22.9 1.5 0.036 12.2 0.0 4.3 5 0 0 5 5 5 2 Nucleoporin Nup120/160 Utp13 PF08625.6 EEQ32939.1 - 0.021 14.4 0.6 0.045 13.4 0.0 1.8 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain DUF3312 PF11768.3 EEQ32939.1 - 0.029 12.6 0.0 0.21 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 EEQ32939.1 - 0.095 11.4 3.8 24 3.5 0.0 4.9 2 2 1 4 4 4 0 Nup133 N terminal like P34-Arc PF04045.9 EEQ32940.1 - 8.9e-100 332.9 0.0 1.1e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EEQ32940.1 - 0.029 13.7 0.1 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Hemerythrin PF01814.18 EEQ32940.1 - 0.099 12.8 2.3 5.9 7.0 0.3 2.2 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain PP2C PF00481.16 EEQ32942.1 - 3.6e-05 23.2 0.0 0.072 12.4 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EEQ32942.1 - 0.0003 20.2 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EEQ32942.1 - 0.0017 18.0 0.1 0.0093 15.6 0.1 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Fcf1 PF04900.7 EEQ32943.1 - 2.1e-12 47.0 3.6 1.4e-05 25.1 0.1 3.6 3 1 0 3 3 3 2 Fcf1 Cmc1 PF08583.5 EEQ32944.1 - 4.9e-18 64.6 6.4 5.7e-18 64.4 4.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Gemini_AL2 PF01440.11 EEQ32944.1 - 0.089 12.8 0.2 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Geminivirus AL2 protein Prolamin_like PF05617.6 EEQ32944.1 - 0.15 12.2 1.0 0.19 11.8 0.7 1.4 1 1 0 1 1 1 0 Prolamin-like GCK PF07802.6 EEQ32944.1 - 0.26 11.4 3.0 0.38 10.8 1.5 1.7 1 1 0 1 1 1 0 GCK domain HECA PF15353.1 EEQ32944.1 - 0.74 9.5 4.6 1.1 9.0 3.2 1.3 1 1 0 1 1 1 0 Headcase protein family homologue WD40 PF00400.27 EEQ32945.1 - 1.8e-22 78.3 16.0 1.6e-07 30.9 0.3 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Astro_capsid PF03115.9 EEQ32945.1 - 2.8 6.0 6.1 4.4 5.4 4.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor APH PF01636.18 EEQ32946.1 - 3e-12 46.7 0.0 1.3e-11 44.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEQ32946.1 - 0.0062 15.5 0.1 0.019 13.9 0.0 1.7 2 0 0 2 2 2 1 Fructosamine kinase Choline_kinase PF01633.15 EEQ32946.1 - 0.0095 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RRN3 PF05327.6 EEQ32949.1 - 4.1e-142 474.1 0.0 1.6e-137 459.0 0.0 2.9 1 1 2 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_3 PF07859.8 EEQ32950.1 - 4.4e-40 137.5 0.2 6.3e-31 107.5 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 EEQ32950.1 - 3.4e-10 39.2 0.1 7.1e-10 38.2 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EEQ32950.1 - 0.0039 16.9 0.1 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3439 PF11921.3 EEQ32950.1 - 0.021 14.5 2.4 0.2 11.4 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF2974 PF11187.3 EEQ32950.1 - 0.028 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Mucin PF01456.12 EEQ32950.1 - 0.028 14.1 4.6 0.044 13.5 3.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Esterase PF00756.15 EEQ32950.1 - 0.032 13.6 0.3 0.062 12.7 0.2 1.6 1 1 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 EEQ32950.1 - 0.078 11.8 0.0 0.13 11.1 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme tRNA-synt_2 PF00152.15 EEQ32951.1 - 5.3e-77 258.8 0.0 7.4e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EEQ32951.1 - 7.6e-20 70.9 0.0 1.1e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 EEQ32951.1 - 0.00032 19.9 0.1 0.6 9.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EEQ32951.1 - 0.00049 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Fer4_12 PF13353.1 EEQ32951.1 - 0.12 12.4 0.0 55 3.8 0.0 3.1 2 1 1 3 3 3 0 4Fe-4S single cluster domain Fer4_14 PF13394.1 EEQ32951.1 - 0.13 12.3 0.0 2.7 8.0 0.0 2.5 1 1 1 2 2 2 0 4Fe-4S single cluster domain Ank_2 PF12796.2 EEQ32953.1 - 7.8e-45 151.1 13.7 5.6e-14 52.2 0.2 5.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ32953.1 - 3.2e-27 92.9 10.7 9.6e-06 25.1 0.1 7.9 6 1 1 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 EEQ32953.1 - 7.9e-25 86.7 6.7 1e-06 29.0 0.0 7.1 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ32953.1 - 2.4e-20 70.5 4.7 0.0005 20.0 0.0 8.5 8 1 1 9 9 9 4 Ankyrin repeat Ank_5 PF13857.1 EEQ32953.1 - 6e-14 51.7 9.6 0.42 10.9 0.0 8.1 2 2 5 8 8 8 5 Ankyrin repeats (many copies) DUF3447 PF11929.3 EEQ32953.1 - 0.0014 18.3 0.0 0.76 9.6 0.0 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Shigella_OspC PF06128.6 EEQ32953.1 - 0.15 11.4 0.0 12 5.3 0.0 2.8 2 1 1 3 3 3 0 Shigella flexneri OspC protein HLH PF00010.21 EEQ32954.1 - 6.8e-14 51.3 1.7 7.6e-14 51.1 0.1 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain XRCC4 PF06632.7 EEQ32955.1 - 0.073 11.9 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Septin PF00735.13 EEQ32957.1 - 8.4e-08 31.5 0.4 2.2e-07 30.1 0.0 1.8 3 0 0 3 3 3 1 Septin HSP90 PF00183.13 EEQ32958.1 - 9.5e-253 839.4 34.6 1.1e-252 839.1 24.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EEQ32958.1 - 1.9e-11 43.6 0.1 3.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EEQ32958.1 - 3.3e-10 39.7 0.3 3.3e-10 39.7 0.2 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EEQ32958.1 - 0.036 13.8 0.2 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Tumour suppressor protein NTF2 PF02136.15 EEQ32959.1 - 3.2e-22 79.1 0.4 5.5e-22 78.3 0.3 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EEQ32959.1 - 1.3e-08 34.3 0.1 2.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ32959.1 - 1.8e-06 27.7 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ32959.1 - 6.3e-06 25.9 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEQ32959.1 - 0.0084 15.9 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif DUF3275 PF11679.3 EEQ32959.1 - 0.0097 15.5 1.3 0.0097 15.5 0.9 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF3275) BssS PF13991.1 EEQ32960.1 - 0.073 12.8 0.1 0.23 11.2 0.0 1.9 2 1 1 3 3 3 0 BssS protein family TPR_11 PF13414.1 EEQ32961.1 - 4.5e-06 26.2 2.1 0.019 14.5 0.1 4.2 4 1 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 EEQ32961.1 - 0.00095 19.7 5.5 3.5 8.4 0.0 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ32961.1 - 0.0016 18.4 0.2 2 8.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ32961.1 - 0.0053 17.2 4.9 39 5.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ32961.1 - 0.038 13.9 0.8 1.6 8.8 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ32961.1 - 0.071 13.4 2.0 7.1 7.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DALR_2 PF09190.6 EEQ32961.1 - 0.087 13.0 0.5 2.3 8.5 0.2 2.7 2 0 0 2 2 2 0 DALR domain TPR_1 PF00515.23 EEQ32961.1 - 0.093 12.3 0.5 4.1 7.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ32961.1 - 0.88 9.5 6.3 6.2 6.8 0.2 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Nnf1 PF03980.9 EEQ32962.1 - 7.8e-27 93.4 0.2 2e-26 92.1 0.1 1.7 1 0 0 1 1 1 1 Nnf1 HAUS4 PF14735.1 EEQ32962.1 - 0.013 14.8 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Microtub_assoc PF07989.6 EEQ32962.1 - 0.036 13.8 1.4 0.093 12.5 1.0 1.7 1 0 0 1 1 1 0 Microtubule associated THOC7 PF05615.8 EEQ32962.1 - 0.05 13.8 1.0 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 bZIP_1 PF00170.16 EEQ32962.1 - 2.2 8.2 5.5 1.3 9.0 1.9 2.1 3 0 0 3 3 3 0 bZIP transcription factor Pkinase PF00069.20 EEQ32963.1 - 1.7e-69 233.8 0.0 2.7e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32963.1 - 1.7e-32 112.4 0.2 3.1e-32 111.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ32963.1 - 0.00048 19.1 0.6 0.0032 16.4 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EEQ32963.1 - 0.028 14.1 2.9 0.042 13.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ32963.1 - 0.13 11.8 0.1 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 EEQ32963.1 - 0.55 9.2 5.9 0.058 12.4 0.2 2.1 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIR2 PF02146.12 EEQ32964.1 - 2.7e-35 121.7 0.0 4.8e-35 120.8 0.0 1.4 1 1 0 1 1 1 1 Sir2 family AATase PF07247.7 EEQ32965.1 - 3.2e-24 85.3 0.0 5e-24 84.7 0.0 1.3 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EEQ32965.1 - 3.4e-10 39.2 0.0 5.5e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 Condensation domain Cation_efflux PF01545.16 EEQ32966.1 - 2e-56 191.2 0.4 2.4e-56 190.8 0.3 1.1 1 0 0 1 1 1 1 Cation efflux family Herpes_TK PF00693.13 EEQ32966.1 - 0.036 13.2 0.5 0.059 12.5 0.3 1.2 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus TrkH PF02386.11 EEQ32966.1 - 0.059 11.9 0.2 0.091 11.3 0.1 1.2 1 0 0 1 1 1 0 Cation transport protein FGGY_C PF02782.11 EEQ32967.1 - 7e-31 107.3 0.0 1.3e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEQ32967.1 - 1.9e-14 53.5 0.0 3.8e-06 26.4 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.7 EEQ32968.1 - 1.8e-38 131.7 0.3 1.8e-38 131.7 0.2 2.7 3 0 0 3 3 3 1 Exportin 1-like protein SEO_N PF14576.1 EEQ32968.1 - 0.0059 15.9 0.1 0.02 14.1 0.1 1.9 1 0 0 1 1 1 1 Sieve element occlusion N-terminus HEAT PF02985.17 EEQ32968.1 - 0.024 14.6 0.0 41 4.6 0.0 4.6 3 0 0 3 3 3 0 HEAT repeat Nop14 PF04147.7 EEQ32968.1 - 0.27 9.1 0.0 1.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Nop14-like family TipAS PF07739.8 EEQ32968.1 - 0.84 9.9 3.2 23 5.3 0.0 4.2 5 0 0 5 5 5 0 TipAS antibiotic-recognition domain Esterase PF00756.15 EEQ32969.1 - 9.8e-53 179.1 0.0 1.2e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EEQ32969.1 - 8.7e-06 25.5 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ32969.1 - 2.5e-05 24.2 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EEQ32969.1 - 0.00066 18.9 0.0 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EEQ32969.1 - 0.00084 18.6 0.0 0.0013 17.9 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EEQ32969.1 - 0.0066 16.0 0.1 0.27 10.7 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EEQ32969.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.2 EEQ32969.1 - 0.028 13.3 0.0 0.05 12.4 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 EEQ32969.1 - 0.032 13.7 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 EEQ32969.1 - 0.043 13.1 0.1 0.14 11.4 0.1 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EEQ32969.1 - 0.12 11.9 0.0 0.53 9.8 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_C50 PF03568.12 EEQ32970.1 - 2.8e-118 394.9 0.0 1.6e-117 392.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.1 EEQ32970.1 - 0.0018 18.1 12.0 1.2 9.1 0.0 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ32970.1 - 0.0038 17.0 1.8 4.1 7.5 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3835 PF12927.2 EEQ32971.1 - 0.01 16.7 0.9 0.022 15.6 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3835) RHD3 PF05879.7 EEQ32971.1 - 0.012 13.5 0.0 0.015 13.2 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Fungal_trans PF04082.13 EEQ32975.1 - 1.7e-22 79.5 1.7 2.2e-22 79.1 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ32975.1 - 5.3e-09 35.8 11.9 1.1e-08 34.8 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EEQ32976.1 - 5.7e-62 209.7 0.0 7.3e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EEQ32978.1 - 1.1e-13 51.0 0.0 2.8e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 EEQ32979.1 - 9.3e-31 106.8 0.1 2e-16 59.5 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 DUF1387 PF07139.6 EEQ32980.1 - 0.14 11.7 1.9 2.1 7.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) MFS_1 PF07690.11 EEQ32982.1 - 1e-37 129.7 46.2 4.2e-35 121.1 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ32982.1 - 4.4e-08 32.1 6.9 4.4e-08 32.1 4.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EEQ32982.1 - 0.0012 17.2 3.9 0.0012 17.2 2.7 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 EEQ32982.1 - 0.002 16.3 0.9 0.002 16.3 0.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EEQ32982.1 - 0.056 13.2 3.9 0.062 13.1 0.0 2.9 2 1 0 2 2 2 0 MFS_1 like family TFR_dimer PF04253.10 EEQ32983.1 - 2.9e-17 62.4 0.0 4.8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EEQ32983.1 - 5e-16 58.9 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EEQ32983.1 - 1.6e-06 27.7 0.0 3.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 PA domain Seadorna_Vp10 PF07322.6 EEQ32983.1 - 0.051 12.8 0.1 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Seadornavirus Vp10 Nicastrin PF05450.10 EEQ32983.1 - 0.053 12.7 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Nicastrin DUF3827 PF12877.2 EEQ32984.1 - 0.012 13.7 1.5 0.023 12.8 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Axin_b-cat_bind PF08833.5 EEQ32984.1 - 0.092 12.4 0.0 0.092 12.4 0.0 3.0 3 0 0 3 3 3 0 Axin beta-catenin binding domain zf-C2H2_4 PF13894.1 EEQ32985.1 - 0.043 14.1 1.4 0.76 10.2 0.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger CMD PF02627.15 EEQ32986.1 - 3.2e-08 33.2 0.1 1e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF1203 PF06718.6 EEQ32986.1 - 0.12 12.2 0.1 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) CBFD_NFYB_HMF PF00808.18 EEQ32987.1 - 4.1e-23 81.2 1.5 7.6e-23 80.3 1.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ32987.1 - 8.9e-05 22.5 0.1 0.00027 21.0 0.1 1.8 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EEQ32987.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.11 EEQ32987.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Prefoldin_2 PF01920.15 EEQ32988.1 - 2.4e-24 85.1 6.3 2.7e-24 84.9 4.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EEQ32988.1 - 0.006 16.2 4.3 0.02 14.5 0.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit DASH_Dad3 PF08656.5 EEQ32988.1 - 0.0063 16.1 1.9 0.019 14.6 0.2 2.0 2 0 0 2 2 2 1 DASH complex subunit Dad3 Borrelia_lipo_1 PF05714.6 EEQ32988.1 - 0.037 13.1 3.7 0.064 12.3 2.5 1.6 1 1 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein FH2 PF02181.18 EEQ32988.1 - 0.059 12.2 2.8 2.7 6.7 0.1 2.0 1 1 0 2 2 2 0 Formin Homology 2 Domain Tho2 PF11262.3 EEQ32988.1 - 0.087 11.8 1.5 0.88 8.5 1.0 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GAS PF13851.1 EEQ32988.1 - 0.09 11.9 6.5 0.22 10.6 4.5 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding p25-alpha PF05517.7 EEQ32988.1 - 0.092 12.9 0.8 1.3 9.2 0.0 2.0 2 0 0 2 2 2 0 p25-alpha DUF2205 PF10224.4 EEQ32988.1 - 0.1 12.1 5.9 0.32 10.5 0.4 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) PMC2NT PF08066.7 EEQ32988.1 - 0.18 12.1 1.6 0.92 9.8 0.1 2.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain TroA PF01297.12 EEQ32988.1 - 0.2 10.9 1.3 2 7.6 0.1 2.0 2 0 0 2 2 2 0 Periplasmic solute binding protein family GrpE PF01025.14 EEQ32988.1 - 0.24 10.9 3.4 0.56 9.7 0.1 2.0 2 0 0 2 2 2 0 GrpE DUF342 PF03961.8 EEQ32988.1 - 0.42 8.9 3.1 0.59 8.4 2.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 EEQ32988.1 - 0.6 10.2 4.1 0.96 9.5 2.8 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc24 PF08286.6 EEQ32988.1 - 0.88 9.2 7.4 2.3 7.9 0.6 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 bZIP_1 PF00170.16 EEQ32988.1 - 1 9.3 4.7 8.9 6.3 0.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 EEQ32988.1 - 2.8 7.5 5.3 13 5.3 3.7 1.8 1 1 0 1 1 1 0 IncA protein Fungal_trans PF04082.13 EEQ32989.1 - 7.3e-16 57.8 0.0 2.7e-15 55.9 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ32989.1 - 1.6e-09 37.5 11.0 2.7e-09 36.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TF_Zn_Ribbon PF08271.7 EEQ32989.1 - 3.6 6.9 7.3 0.16 11.2 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Aminotran_1_2 PF00155.16 EEQ32990.1 - 6.6e-18 64.7 0.0 1.1e-17 64.0 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EEQ32990.1 - 0.023 13.2 0.0 0.11 11.0 0.0 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 EEQ32990.1 - 0.046 12.8 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEQ32990.1 - 0.13 11.2 0.1 0.44 9.5 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.20 EEQ32991.1 - 1e-41 142.8 0.0 1.6e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32991.1 - 1.8e-30 105.8 0.0 3e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EEQ32993.1 - 1.1e-62 211.5 0.0 1.8e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ32993.1 - 6.4e-28 97.5 0.0 1.3e-27 96.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ32993.1 - 0.00019 20.5 0.0 0.00029 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EEQ32993.1 - 0.0037 16.6 0.0 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EEQ32993.1 - 0.0044 16.1 0.0 0.0095 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ32993.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family UQ_con PF00179.21 EEQ32994.1 - 2.5e-25 88.5 0.0 3e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ32994.1 - 1.5e-05 24.7 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ32994.1 - 8e-05 22.5 0.1 9.9e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 RWD domain Complex1_49kDa PF00346.14 EEQ32995.1 - 3e-133 442.9 0.0 3.9e-133 442.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 EEQ32996.1 - 1.6e-25 89.3 0.0 3.1e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEQ32996.1 - 3.1e-13 48.6 0.0 4.1e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 EEQ32997.1 - 1.6e-36 125.1 0.1 4.3e-36 123.7 0.0 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EEQ32997.1 - 1.3e-29 101.7 0.1 2.4e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EEQ32997.1 - 4.4e-24 83.8 0.2 1.3e-23 82.3 0.2 1.8 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EEQ32997.1 - 7.4e-14 50.8 1.5 7.4e-14 50.8 1.0 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EEQ32997.1 - 0.00062 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 EEQ32997.1 - 0.0074 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 EEQ32997.1 - 0.071 13.0 1.5 0.16 11.8 1.0 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Pro_dh PF01619.13 EEQ32997.1 - 0.12 11.3 0.1 0.25 10.2 0.0 1.5 2 0 0 2 2 2 0 Proline dehydrogenase Telomere_reg-2 PF10193.4 EEQ32998.1 - 2.4e-31 108.3 0.0 6.2e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Ebola_NP PF05505.7 EEQ32998.1 - 0.53 8.2 3.2 0.79 7.7 2.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Fungal_trans PF04082.13 EEQ32999.1 - 2.2e-25 89.0 0.2 3.6e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ32999.1 - 5.3e-09 35.8 11.8 1.1e-08 34.8 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_2 PF00890.19 EEQ33000.1 - 8.3e-08 31.4 0.0 0.0064 15.3 0.0 2.2 1 1 0 2 2 2 2 FAD binding domain zf-H2C2_2 PF13465.1 EEQ33005.1 - 6e-12 45.2 14.5 4.1e-06 26.7 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ33005.1 - 2.3e-10 40.1 11.2 9.7e-06 25.6 3.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ33005.1 - 1.3e-07 31.4 8.0 0.00011 22.3 1.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EEQ33005.1 - 1.7e-06 27.9 2.4 1.9e-05 24.6 0.9 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ33005.1 - 1.5e-05 24.9 6.0 0.0001 22.3 1.5 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ33005.1 - 0.00034 20.4 7.3 0.0071 16.2 1.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EEQ33005.1 - 0.11 12.1 4.0 5.6 6.7 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EEQ33005.1 - 0.32 10.8 5.5 0.093 12.5 0.6 2.1 2 0 0 2 2 2 0 BED zinc finger V-SNARE_C PF12352.3 EEQ33006.1 - 1.1 9.3 6.9 0.083 12.9 0.6 2.2 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Sec1 PF00995.18 EEQ33007.1 - 3.4e-132 441.9 0.0 4.2e-132 441.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SF3b1 PF08920.5 EEQ33008.1 - 5.1e-41 140.1 0.2 5.1e-41 140.1 0.1 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EEQ33008.1 - 9.2e-14 51.4 4.8 0.011 16.0 0.0 7.2 5 3 2 7 7 7 4 HEAT repeats HEAT PF02985.17 EEQ33008.1 - 2.8e-10 39.3 9.9 1 9.6 0.0 9.3 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EEQ33008.1 - 1.3e-08 35.0 5.7 0.54 10.8 0.0 7.1 5 2 2 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ33008.1 - 1.5e-05 25.3 0.2 1.1 9.6 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.7 EEQ33008.1 - 0.0055 16.0 0.1 4.4 6.6 0.0 3.7 3 0 0 3 3 3 1 NUC173 domain CLASP_N PF12348.3 EEQ33008.1 - 0.0097 15.2 0.2 1.1 8.6 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal CRM1_C PF08767.6 EEQ33008.1 - 0.16 10.8 0.8 0.64 8.8 0.0 2.3 3 0 0 3 3 3 0 CRM1 C terminal DUF3455 PF11937.3 EEQ33009.1 - 3.4e-29 102.0 0.0 4.6e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Methyltransf_11 PF08241.7 EEQ33010.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EEQ33010.1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family SAP PF02037.22 EEQ33011.1 - 4.8e-12 45.0 0.1 1.2e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 SAP domain CCT_2 PF09425.5 EEQ33011.1 - 0.073 12.6 5.5 2.7 7.6 0.8 2.8 2 0 0 2 2 2 0 Divergent CCT motif IER PF05760.7 EEQ33011.1 - 0.2 11.5 12.4 0.27 11.1 8.6 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) CDC27 PF09507.5 EEQ33011.1 - 1.1 8.4 17.0 1.2 8.2 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SSrecog PF03531.9 EEQ33012.1 - 6.6e-70 234.9 1.7 1e-68 231.0 1.2 2.6 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EEQ33012.1 - 1e-27 95.9 0.2 4.1e-27 94.0 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Rax2 PF12768.2 EEQ33013.1 - 6.2e-101 337.2 3.9 7.7e-93 310.7 0.0 4.8 5 0 0 5 5 5 4 Cortical protein marker for cell polarity Reg_prop PF07494.6 EEQ33013.1 - 0.89 9.7 6.9 15 6.0 0.0 5.8 7 0 0 7 7 7 0 Two component regulator propeller Zn_clus PF00172.13 EEQ33014.1 - 6.4e-09 35.5 11.1 1.3e-08 34.6 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEQ33014.1 - 1.3e-07 30.5 0.0 1.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 EEQ33015.1 - 5e-24 85.4 0.0 2.9e-22 79.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ33015.1 - 5.8e-10 37.9 1.3 5.3e-09 34.8 0.3 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.19 EEQ33015.1 - 6e-10 38.5 0.0 0.00049 19.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EEQ33015.1 - 1.6e-09 37.1 0.9 4.8e-05 22.4 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEQ33015.1 - 5.5e-09 35.9 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ33015.1 - 4.3e-08 33.2 0.0 0.00022 21.1 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ33015.1 - 7.1e-05 22.6 0.0 0.07 12.8 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 EEQ33015.1 - 8.2e-05 21.8 0.0 0.0017 17.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.10 EEQ33015.1 - 0.0072 14.5 0.0 1.5 6.9 0.0 2.4 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.9 EEQ33015.1 - 0.011 14.1 0.2 0.95 7.8 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.7 EEQ33015.1 - 0.012 14.5 0.0 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 EEQ33015.1 - 0.021 13.7 0.0 0.55 9.0 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EEQ33015.1 - 0.037 12.8 0.0 0.082 11.7 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain OGG_N PF07934.7 EEQ33016.1 - 4e-26 91.2 0.1 9.3e-26 90.0 0.1 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EEQ33016.1 - 1.1e-15 57.7 0.0 1.9e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEQ33016.1 - 0.00061 19.3 0.0 0.0018 17.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 EEQ33017.1 - 8.6e-30 102.1 0.2 1.4e-12 47.0 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ33017.1 - 1.5e-21 76.1 0.0 2e-05 24.4 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ33017.1 - 3.1e-17 62.1 0.0 5.8e-08 32.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_2 PF00002.19 EEQ33018.1 - 0.00074 18.6 8.9 0.0019 17.3 6.2 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) DUF1751 PF08551.5 EEQ33018.1 - 0.015 15.6 0.9 0.015 15.6 0.6 2.2 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) DUF3082 PF11282.3 EEQ33018.1 - 0.027 14.5 1.5 0.072 13.1 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3082) Chromate_transp PF02417.10 EEQ33019.1 - 1.5e-46 158.0 33.7 2.7e-24 85.6 8.7 2.4 3 0 0 3 3 3 2 Chromate transporter Ribosomal_S13_N PF08069.7 EEQ33020.1 - 6.9e-30 102.6 0.2 1.4e-29 101.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EEQ33020.1 - 7.3e-22 76.9 0.1 1.3e-21 76.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S15 PAX PF00292.13 EEQ33020.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain VRR_NUC PF08774.6 EEQ33021.1 - 4.3e-17 61.9 0.0 1.1e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.8 EEQ33022.1 - 1.3e-13 50.1 0.0 1.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Drf_FH1 PF06346.7 EEQ33022.1 - 0.019 14.4 5.6 0.034 13.6 3.9 1.4 1 0 0 1 1 1 0 Formin Homology Region 1 RRM_1 PF00076.17 EEQ33023.1 - 1.8e-19 69.0 0.0 3.1e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ33023.1 - 9.7e-18 63.9 0.0 1.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ33023.1 - 1.4e-12 47.2 0.0 2.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EEQ33023.1 - 0.00012 21.8 1.0 0.00017 21.3 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) GlyL_C PF12524.3 EEQ33023.1 - 0.15 11.9 4.7 0.31 10.9 3.2 1.5 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal zf-HC5HC2H_2 PF13832.1 EEQ33024.1 - 7.2e-33 112.8 3.0 7.2e-33 112.8 2.1 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEQ33024.1 - 8.5e-28 96.3 0.9 8.5e-28 96.3 0.6 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EEQ33024.1 - 5.1e-25 88.5 0.0 5.1e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EEQ33024.1 - 5.3e-14 51.2 3.2 5.3e-14 51.2 2.2 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EEQ33024.1 - 1.9e-08 33.8 23.7 7.4e-08 31.9 6.9 2.6 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.20 EEQ33024.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Bromodomain zf-PHD-like PF15446.1 EEQ33024.1 - 6.2 6.0 13.4 0.034 13.4 2.3 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Myb_DNA-bind_6 PF13921.1 EEQ33026.1 - 1.5e-09 37.7 0.9 1.2e-08 34.9 0.2 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ33026.1 - 0.00055 19.9 0.1 0.0025 17.8 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Peptidase_M22 PF00814.20 EEQ33027.1 - 9.6e-45 153.1 0.0 9.8e-40 136.7 0.0 3.7 2 1 0 2 2 2 2 Glycoprotease family Glyco_transf_25 PF01755.12 EEQ33029.1 - 3.2e-08 33.4 0.0 2.1e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Mid2 PF04478.7 EEQ33030.1 - 0.0039 16.6 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4448 PF14610.1 EEQ33030.1 - 0.016 14.7 0.6 0.046 13.2 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.5 EEQ33030.1 - 0.024 13.9 0.5 0.051 12.9 0.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pyr_redox_3 PF13738.1 EEQ33031.1 - 2.1e-23 83.4 0.0 3.2e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ33031.1 - 4.3e-12 45.0 0.4 1.2e-10 40.3 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EEQ33031.1 - 5e-12 45.6 0.0 3.8e-08 33.2 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ33031.1 - 1.2e-06 27.7 0.2 0.027 13.3 0.0 3.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EEQ33031.1 - 3.3e-06 26.2 0.0 1.6e-05 23.9 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEQ33031.1 - 3.5e-06 27.0 0.0 0.011 15.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ33031.1 - 1.6e-05 25.2 0.1 0.043 14.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ33031.1 - 0.00053 19.7 1.9 2 8.1 0.2 4.0 3 2 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EEQ33031.1 - 0.013 14.6 0.1 0.21 10.6 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EEQ33031.1 - 0.018 13.9 0.0 0.3 9.8 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 EEQ33031.1 - 0.034 14.3 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EEQ33031.1 - 0.036 14.1 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EEQ33031.1 - 0.063 12.1 0.2 1.8 7.3 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EEQ33031.1 - 0.12 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EEQ33031.1 - 0.13 10.6 0.2 6.9 5.0 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_2 PF03446.10 EEQ33031.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pkinase PF00069.20 EEQ33033.1 - 4e-15 55.6 0.0 3.4e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33033.1 - 1.3e-05 24.4 0.1 0.18 10.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Mito_carr PF00153.22 EEQ33035.1 - 3.8e-75 247.6 0.7 1e-25 89.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EEQ33035.1 - 1.6e-12 46.1 4.4 2.8e-07 29.8 0.1 5.7 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 EEQ33035.1 - 2.8e-12 46.6 6.0 3.8e-08 33.3 1.0 4.1 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EEQ33035.1 - 1.8e-11 42.4 9.9 3.9e-07 28.9 0.1 5.5 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 EEQ33035.1 - 3.5e-10 39.3 2.0 0.1 12.2 0.0 4.9 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EEQ33035.1 - 4.1e-08 32.1 8.0 3.3e-05 23.0 0.1 4.9 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.1 EEQ33035.1 - 0.08 12.8 0.0 9.1 6.2 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain DUF726 PF05277.7 EEQ33037.1 - 1.6e-93 313.3 0.0 2e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) RTC4 PF14474.1 EEQ33038.1 - 1.7e-37 128.1 0.1 2.5e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain Tmemb_14 PF03647.8 EEQ33039.1 - 3.4e-22 78.6 8.2 4e-22 78.4 5.7 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DAD PF02109.11 EEQ33040.1 - 2.8e-40 136.8 3.6 3.5e-39 133.3 2.5 1.9 1 1 0 1 1 1 1 DAD family HA2 PF04408.18 EEQ33041.1 - 3.3e-24 84.8 0.0 1.8e-23 82.5 0.0 2.3 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEQ33041.1 - 2.3e-14 53.1 0.1 6.8e-08 32.3 0.0 3.4 2 1 1 3 3 3 2 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEQ33041.1 - 5.3e-14 51.8 0.0 1.8e-13 50.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ33041.1 - 1.6e-06 27.7 0.1 3.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EEQ33041.1 - 0.00028 19.8 0.0 0.0014 17.5 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 EEQ33041.1 - 0.00059 19.9 0.1 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EEQ33041.1 - 0.0014 18.5 0.0 0.68 9.7 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EEQ33041.1 - 0.0059 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EEQ33041.1 - 0.0066 15.5 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC SRP54 PF00448.17 EEQ33041.1 - 0.011 15.2 0.2 0.032 13.6 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EEQ33041.1 - 0.011 15.5 0.2 0.072 12.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EEQ33041.1 - 0.033 12.8 0.2 0.074 11.7 0.1 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Flavi_DEAD PF07652.9 EEQ33041.1 - 0.048 13.4 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain NACHT PF05729.7 EEQ33041.1 - 0.073 12.7 1.5 0.72 9.4 0.1 2.5 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.1 EEQ33041.1 - 0.074 13.3 0.6 0.68 10.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain Glug PF07581.7 EEQ33041.1 - 0.086 13.0 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 The GLUG motif DUF2413 PF10310.4 EEQ33043.1 - 1.2e-132 442.9 0.0 1.4e-132 442.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DUF605 PF04652.11 EEQ33043.1 - 2.5 7.4 11.7 4 6.7 8.1 1.3 1 0 0 1 1 1 0 Vta1 like DUF2462 PF09495.5 EEQ33044.1 - 2.5e-19 69.7 17.0 3.1e-19 69.4 11.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Gly_transf_sug PF04488.10 EEQ33045.1 - 1e-09 38.6 0.9 2e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EEQ33045.1 - 0.022 13.9 0.1 0.022 13.9 0.0 2.0 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein Borrelia_P83 PF05262.6 EEQ33045.1 - 0.036 12.3 15.7 0.049 11.8 10.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.7 EEQ33045.1 - 0.94 9.3 14.9 1.7 8.4 10.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 EEQ33045.1 - 1.3 7.0 13.8 1.5 6.7 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP_sp32 PF07222.7 EEQ33045.1 - 2.1 7.4 10.6 3.7 6.6 7.3 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Vfa1 PF08432.5 EEQ33045.1 - 3.7 7.5 25.1 6.3 6.7 17.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 EEQ33045.1 - 3.9 6.9 20.6 5.9 6.3 14.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pro_CA PF00484.14 EEQ33045.1 - 4.4 7.2 5.4 8.7 6.3 3.8 1.4 1 0 0 1 1 1 0 Carbonic anhydrase DUF16 PF01519.11 EEQ33046.1 - 0.0022 18.1 3.8 0.0039 17.3 2.6 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 DUF641 PF04859.7 EEQ33046.1 - 0.092 12.5 5.6 0.23 11.2 3.9 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) NPV_P10 PF05531.7 EEQ33046.1 - 0.12 12.6 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EEQ33046.1 - 0.19 10.8 10.9 0.47 9.6 7.5 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4618 PF15397.1 EEQ33046.1 - 0.26 10.5 6.4 0.46 9.7 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) End3 PF12761.2 EEQ33046.1 - 0.48 10.0 6.9 0.9 9.1 4.8 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Tropomyosin_1 PF12718.2 EEQ33046.1 - 0.48 10.2 19.7 0.2 11.4 9.2 2.3 1 1 1 2 2 2 0 Tropomyosin like Prefoldin_2 PF01920.15 EEQ33046.1 - 2.9 7.7 11.8 11 5.8 3.7 2.6 1 1 1 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.5 EEQ33046.1 - 2.9 8.0 4.3 9.3 6.3 2.9 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Peptidase_S8 PF00082.17 EEQ33048.1 - 5e-20 71.8 0.0 7.9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Subtilase family WD40 PF00400.27 EEQ33048.1 - 2.1e-14 52.7 13.0 0.0016 18.2 0.0 7.2 9 0 0 9 9 9 4 WD domain, G-beta repeat NACHT PF05729.7 EEQ33048.1 - 2.4e-10 40.3 0.2 5.4e-09 35.9 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EEQ33048.1 - 1.1e-06 28.7 0.2 9.6e-06 25.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ33048.1 - 0.00049 20.2 0.1 0.0019 18.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain TruB_C PF09142.6 EEQ33048.1 - 0.00054 19.5 0.1 1.2 8.8 0.0 4.0 4 0 0 4 4 4 1 tRNA Pseudouridine synthase II, C terminal Nbas_N PF15492.1 EEQ33048.1 - 0.01 14.9 0.0 8.4 5.4 0.0 4.2 5 0 0 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Arch_ATPase PF01637.13 EEQ33048.1 - 0.017 14.8 0.1 0.063 12.9 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 EEQ33048.1 - 0.017 14.5 0.0 0.13 11.6 0.0 2.5 1 1 0 1 1 1 0 AAA-like domain AAA PF00004.24 EEQ33048.1 - 0.036 14.2 0.0 0.29 11.3 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 EEQ33048.1 - 0.068 12.1 0.1 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain DPPIV_N PF00930.16 EEQ33048.1 - 0.092 11.3 0.0 1.5 7.2 0.0 2.7 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region UCR_Fe-S_N PF10399.4 EEQ33049.1 - 0.0057 15.8 5.1 0.012 14.7 3.5 1.5 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal RskA PF10099.4 EEQ33049.1 - 0.037 13.7 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Epiglycanin_C PF14654.1 EEQ33049.1 - 0.24 11.3 3.4 0.74 9.8 1.5 2.3 2 1 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Glyco_transf_90 PF05686.7 EEQ33050.1 - 8.5e-37 126.7 6.2 1.7e-36 125.7 4.3 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 OapA_N PF08525.6 EEQ33050.1 - 0.0047 16.6 0.6 0.0082 15.8 0.4 1.3 1 0 0 1 1 1 1 Opacity-associated protein A N-terminal motif Glyco_trans_1_2 PF13524.1 EEQ33050.1 - 0.023 14.9 0.2 0.07 13.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 GPI-anchored PF10342.4 EEQ33052.1 - 3.4e-25 88.3 0.2 3.4e-25 88.3 0.2 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EEQ33052.1 - 0.0042 16.6 0.3 0.0064 15.9 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) fn3 PF00041.16 EEQ33052.1 - 0.0071 16.4 0.5 0.035 14.2 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III domain Tachystatin_B PF11478.3 EEQ33053.1 - 0.058 13.1 0.4 0.13 11.9 0.1 1.7 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B GST_C_2 PF13410.1 EEQ33054.1 - 5.6e-05 22.9 1.0 0.00011 22.0 0.7 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ33054.1 - 0.0014 18.7 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ33054.1 - 0.017 15.1 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEQ33054.1 - 0.023 14.7 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Cellulase PF00150.13 EEQ33055.1 - 8.2e-16 58.0 0.0 7.9e-14 51.5 0.0 2.3 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) IBN_N PF03810.14 EEQ33056.1 - 1.1e-12 47.7 0.0 4.9e-12 45.5 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EEQ33056.1 - 0.00029 20.7 0.8 0.039 13.8 0.0 3.7 3 1 0 3 3 3 1 Exportin 1-like protein Pex2_Pex12 PF04757.9 EEQ33057.1 - 7.9e-32 110.5 0.2 7.9e-32 110.5 0.1 1.4 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EEQ33057.1 - 0.0063 16.3 4.2 0.0063 16.3 2.9 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EEQ33057.1 - 0.022 14.4 1.4 0.058 13.0 1.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ33057.1 - 0.046 13.7 6.8 0.39 10.7 3.0 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEQ33057.1 - 0.14 11.9 3.6 1.1 9.0 0.2 2.4 2 0 0 2 2 2 0 RING-type zinc-finger DUF1772 PF08592.6 EEQ33058.1 - 7.4e-25 87.3 0.2 1.4e-24 86.3 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF3070 PF11270.3 EEQ33058.1 - 0.14 11.9 1.4 0.17 11.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3070) ILVD_EDD PF00920.16 EEQ33059.1 - 9.4e-201 667.7 2.5 1.1e-200 667.5 1.8 1.0 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 EEQ33059.1 - 0.2 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Abhydrolase_6 PF12697.2 EEQ33060.1 - 4.8e-22 78.9 0.3 9.5e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ33060.1 - 6.1e-13 48.7 0.0 1.2e-11 44.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 EEQ33060.1 - 9.7e-11 41.3 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 EEQ33060.1 - 3e-09 36.7 0.0 1.1e-07 31.6 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold PTPlike_phytase PF14566.1 EEQ33060.1 - 0.0002 21.4 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Ser_hydrolase PF06821.8 EEQ33060.1 - 0.0013 18.3 0.0 0.0086 15.6 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.8 EEQ33060.1 - 0.0014 18.2 0.2 0.019 14.5 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Y_phosphatase PF00102.22 EEQ33060.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LCAT PF02450.10 EEQ33060.1 - 0.0065 15.4 0.0 0.017 14.1 0.0 1.6 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 EEQ33060.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 EEQ33060.1 - 0.033 14.0 0.0 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 EEQ33060.1 - 0.033 14.3 0.1 0.064 13.4 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2239 PF09998.4 EEQ33060.1 - 0.058 13.0 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF900 PF05990.7 EEQ33060.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ribosomal_S19e PF01090.14 EEQ33061.1 - 4.4e-57 191.4 0.3 5e-57 191.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Aldo_ket_red PF00248.16 EEQ33063.1 - 5.9e-41 140.1 0.0 1.4e-40 138.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family eRF1_1 PF03463.10 EEQ33064.1 - 1.1e-41 141.5 0.0 3.9e-41 139.7 0.0 1.9 1 1 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EEQ33064.1 - 3.6e-18 65.8 0.0 6.2e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EEQ33064.1 - 6.3e-18 65.3 0.0 3.1e-16 59.8 0.0 2.3 1 1 0 1 1 1 1 eRF1 domain 2 Myb_DNA-bind_4 PF13837.1 EEQ33065.1 - 0.00023 21.2 4.4 0.0022 18.0 0.8 2.6 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain PXPV PF12778.2 EEQ33065.1 - 0.021 14.4 0.1 0.043 13.5 0.1 1.4 1 0 0 1 1 1 0 PXPV repeat (3 copies) Myb_DNA-bind_3 PF12776.2 EEQ33065.1 - 0.81 10.3 6.1 2 9.1 0.4 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ33066.1 - 0.0013 18.7 0.2 0.0023 17.9 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ33066.1 - 0.0027 17.7 0.1 0.0049 16.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ33068.1 - 7.2e-13 48.3 4.6 1.4e-07 31.4 1.8 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ33068.1 - 3.5e-11 43.0 2.0 1.2e-06 28.4 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain PAT1 PF09770.4 EEQ33068.1 - 0.88 7.7 36.3 1.1 7.3 25.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 COX5B PF01215.14 EEQ33069.1 - 7.2e-40 135.8 0.0 9.5e-40 135.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EEQ33069.1 - 0.043 13.3 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Myb_DNA-bind_6 PF13921.1 EEQ33070.1 - 1.3e-13 50.8 0.0 2.4e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ33070.1 - 7.1e-10 38.7 0.0 0.00025 21.0 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain CTP_synth_N PF06418.9 EEQ33072.1 - 2.1e-103 345.2 0.0 3.1e-103 344.6 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EEQ33072.1 - 6.4e-54 182.3 0.0 9.9e-54 181.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEQ33072.1 - 5.2e-07 29.3 0.0 1.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 APH PF01636.18 EEQ33073.1 - 0.0014 18.4 0.0 0.0031 17.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family PROCN PF08083.6 EEQ33074.1 - 2.9e-205 681.4 9.1 1.3e-203 676.0 6.3 2.4 1 1 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EEQ33074.1 - 7.4e-126 418.1 2.9 1.2e-125 417.3 2.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EEQ33074.1 - 5.7e-100 331.3 0.4 2.2e-62 209.1 0.1 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EEQ33074.1 - 8e-78 259.3 3.2 1.1e-77 258.9 1.1 2.2 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EEQ33074.1 - 1.8e-66 221.8 0.2 4e-66 220.7 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 EEQ33074.1 - 3.4e-60 203.4 0.0 1.4e-33 116.4 0.0 3.3 2 1 1 3 3 3 2 Hom_end-associated Hint PROCT PF08084.6 EEQ33074.1 - 2.1e-46 156.6 0.9 3.8e-46 155.8 0.1 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EEQ33074.1 - 5.1e-45 151.2 0.2 1.4e-44 149.8 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end PF05204.9 EEQ33074.1 - 0.00039 20.3 0.0 0.018 15.0 0.0 2.8 2 0 0 2 2 2 1 Homing endonuclease DUF3753 PF12575.3 EEQ33074.1 - 0.16 11.8 0.0 0.45 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 EEQ33074.1 - 0.2 10.4 0.2 0.66 8.6 0.5 1.6 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_L34e PF01199.13 EEQ33075.1 - 1.9e-36 124.1 4.0 2.8e-36 123.6 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EEQ33075.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 EEQ33075.1 - 0.45 10.2 2.9 6.1 6.5 0.2 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain XLF PF09302.6 EEQ33076.1 - 7e-29 100.7 0.1 1.4e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Cactin_mid PF10312.4 EEQ33077.1 - 1.6e-66 223.2 5.3 2.9e-66 222.3 3.7 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EEQ33077.1 - 1.1e-54 183.3 5.7 2.1e-54 182.4 3.9 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Fork_head PF00250.13 EEQ33078.1 - 1.1e-14 54.1 0.2 2.1e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Fork head domain WD40 PF00400.27 EEQ33080.1 - 2.5e-25 87.3 9.7 5.3e-10 38.7 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EEQ33080.1 - 0.0033 17.1 0.0 0.22 11.2 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EEQ33080.1 - 0.0076 15.0 2.4 0.61 8.7 0.2 2.4 1 1 1 2 2 2 2 Nup133 N terminal like THEG PF14912.1 EEQ33081.1 - 1.4 9.5 9.8 4.4 7.9 6.7 2.0 1 1 0 1 1 1 0 Testicular haploid expressed repeat ABC_tran PF00005.22 EEQ33082.1 - 9.3e-33 113.4 0.0 2.2e-32 112.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EEQ33082.1 - 2.2e-17 63.3 16.0 1.5e-10 40.9 0.2 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EEQ33082.1 - 3.2e-07 29.7 0.2 1.1e-05 24.8 0.0 2.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ33082.1 - 0.00019 21.5 0.0 0.22 11.4 0.1 2.2 1 1 1 2 2 2 2 AAA domain SbcCD_C PF13558.1 EEQ33082.1 - 0.0031 17.3 0.4 0.029 14.2 0.3 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EEQ33082.1 - 0.0091 15.5 0.2 0.02 14.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEQ33082.1 - 0.019 15.0 0.2 0.14 12.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEQ33082.1 - 0.02 14.9 0.6 0.094 12.6 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EEQ33082.1 - 0.025 13.7 0.0 0.053 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF498 PF04430.9 EEQ33083.1 - 2.5e-28 97.8 0.0 4.1e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.15 EEQ33084.1 - 5.7e-111 371.1 0.0 6.9e-111 370.9 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EEQ33084.1 - 0.00011 21.6 0.1 0.00029 20.3 0.0 1.6 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EEQ33084.1 - 0.063 13.0 0.1 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Glyco_hydro_16 PF00722.16 EEQ33085.1 - 3.7e-42 143.6 3.1 6.1e-42 143.0 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Desmo_N PF06771.6 EEQ33085.1 - 0.031 14.2 0.2 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus GFA PF04828.9 EEQ33086.1 - 0.0003 20.6 0.1 0.00058 19.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pro_dh PF01619.13 EEQ33088.1 - 4.3e-33 114.6 1.0 6.1e-21 74.7 0.1 2.2 2 0 0 2 2 2 2 Proline dehydrogenase AP-5_subunit_s1 PF15001.1 EEQ33088.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 PMSR PF01625.16 EEQ33089.1 - 1.9e-55 187.0 0.1 2.2e-55 186.7 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF2417 PF10329.4 EEQ33090.1 - 1.5e-79 266.6 0.4 2.3e-79 266.0 0.3 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EEQ33090.1 - 8.7e-08 32.3 0.4 1.4e-07 31.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Scs3p PF10261.4 EEQ33090.1 - 0.084 11.9 0.5 2.8 6.8 0.6 2.2 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Abhydrolase_6 PF12697.2 EEQ33091.1 - 1e-21 77.9 0.1 1.4e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ33091.1 - 1.1e-07 31.6 0.0 2.3e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ33091.1 - 2.2e-07 30.7 0.0 4.6e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ33091.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 EEQ33091.1 - 0.075 13.2 0.0 1.3 9.1 0.0 2.4 1 1 0 1 1 1 0 Thioesterase domain WD40 PF00400.27 EEQ33092.1 - 2e-58 192.3 24.9 7.8e-11 41.4 1.4 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EEQ33092.1 - 3e-42 144.0 0.1 4.5e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EEQ33092.1 - 2.6e-08 32.4 0.8 0.00016 19.9 0.1 3.3 3 0 0 3 3 3 3 Nucleoporin Nup120/160 LisH PF08513.6 EEQ33092.1 - 0.00071 19.2 0.0 0.0023 17.6 0.0 1.9 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 EEQ33092.1 - 0.00092 18.0 0.4 4 6.0 0.0 3.9 3 1 1 4 4 4 2 Nup133 N terminal like Med11 PF10280.4 EEQ33093.1 - 9.4e-32 109.5 0.0 1.6e-31 108.7 0.0 1.4 1 1 0 1 1 1 1 Mediator complex protein F_actin_cap_B PF01115.12 EEQ33094.1 - 1.8e-105 351.4 0.0 2.1e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Helicase_C PF00271.26 EEQ33095.1 - 4.3e-20 71.3 0.0 1.8e-19 69.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ33095.1 - 7.3e-19 67.8 0.0 2.1e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EEQ33095.1 - 2.2e-18 66.7 0.0 6.8e-18 65.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EEQ33095.1 - 0.07 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) V-ATPase_G PF03179.10 EEQ33097.1 - 1.3e-22 80.0 10.9 1.5e-22 79.8 7.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Eno-Rase_FAD_bd PF07055.7 EEQ33097.1 - 0.033 14.1 0.6 0.056 13.3 0.4 1.3 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain U79_P34 PF03064.11 EEQ33097.1 - 0.088 12.3 8.2 0.096 12.2 5.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Borrelia_P83 PF05262.6 EEQ33097.1 - 0.47 8.6 12.9 0.51 8.5 8.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein TRAP_alpha PF03896.11 EEQ33097.1 - 2.6 6.9 6.0 3.2 6.6 4.2 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ATP-synt_B PF00430.13 EEQ33097.1 - 3.9 7.2 11.6 28 4.5 8.4 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DivIVA PF05103.8 EEQ33099.1 - 0.0038 17.2 23.0 0.27 11.2 0.1 3.8 2 1 0 2 2 2 1 DivIVA protein HAP1_N PF04849.8 EEQ33099.1 - 1.3 7.9 31.6 0.86 8.4 0.1 2.6 2 1 0 2 2 2 0 HAP1 N-terminal conserved region DUF972 PF06156.8 EEQ33099.1 - 2.3 8.5 20.9 0.94 9.8 4.3 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) HR1 PF02185.11 EEQ33099.1 - 5 6.9 28.7 2.5 7.8 0.6 4.5 2 1 2 4 4 4 0 Hr1 repeat TBCC PF07986.7 EEQ33100.1 - 9.3e-29 99.2 1.5 1.4e-28 98.6 1.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF1431 PF07248.7 EEQ33100.1 - 0.019 14.9 0.3 0.66 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1431) DUF4325 PF14213.1 EEQ33100.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) JAB PF01398.16 EEQ33101.1 - 2.5e-15 56.1 0.0 4.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EEQ33101.1 - 3e-06 26.7 0.0 8e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 EEQ33101.1 - 4.6e-05 23.3 0.0 9.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain PAT1 PF09770.4 EEQ33101.1 - 0.53 8.4 2.7 0.71 8.0 1.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3439 PF11921.3 EEQ33101.1 - 1.5 8.6 11.4 0.18 11.5 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) BMF PF15185.1 EEQ33103.1 - 0.032 13.5 5.6 0.055 12.7 3.9 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Vps8 PF12816.2 EEQ33104.1 - 7.8e-72 240.6 0.3 2.7e-71 238.8 0.0 2.0 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EEQ33104.1 - 1.2e-09 37.8 1.4 0.00033 20.2 0.1 2.9 2 1 0 2 2 2 2 Region in Clathrin and VPS Pox_D3 PF04580.8 EEQ33104.1 - 0.0047 16.1 0.1 0.012 14.8 0.0 1.6 1 1 0 1 1 1 1 Chordopoxvirinae D3 protein YqzH PF14164.1 EEQ33104.1 - 0.016 15.0 0.1 5.1 7.0 0.0 2.8 2 0 0 2 2 2 0 YqzH-like protein WD40 PF00400.27 EEQ33104.1 - 0.026 14.4 0.1 0.077 12.9 0.1 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-RING_2 PF13639.1 EEQ33104.1 - 0.12 12.1 0.9 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ33104.1 - 0.18 11.8 0.0 0.52 10.3 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HNH_2 PF13391.1 EEQ33105.1 - 6.6e-09 35.4 0.0 1.5e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_16 PF00722.16 EEQ33106.1 - 3.1e-10 39.6 0.1 7.3e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_transf_90 PF05686.7 EEQ33107.1 - 4.4e-14 51.9 0.1 5.5e-07 28.6 0.0 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF3301 PF11743.3 EEQ33107.1 - 0.047 13.2 0.1 0.15 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) GNAT_acetyltr_2 PF13718.1 EEQ33108.1 - 1.4e-80 269.2 0.0 2.3e-80 268.5 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EEQ33108.1 - 3.8e-65 218.8 0.0 8.9e-65 217.6 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EEQ33108.1 - 1.2e-40 137.0 0.1 3.1e-40 135.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EEQ33108.1 - 3.5e-36 123.3 0.3 9.3e-36 121.9 0.2 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 EEQ33108.1 - 0.022 14.8 0.0 0.074 13.0 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ33108.1 - 0.023 14.8 0.0 0.07 13.3 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1741 PF08427.5 EEQ33108.1 - 0.069 12.6 0.1 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) Thioredoxin PF00085.15 EEQ33109.1 - 1.3e-28 98.7 0.0 1.4e-22 79.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EEQ33109.1 - 6.4e-09 35.9 0.3 0.00014 21.9 0.1 3.0 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEQ33109.1 - 7e-07 29.2 0.0 0.00083 19.4 0.0 3.9 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EEQ33109.1 - 0.002 17.8 0.1 0.019 14.6 0.0 2.3 2 1 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EEQ33109.1 - 0.0043 16.5 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EEQ33109.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like FancD2 PF14631.1 EEQ33109.1 - 1.2 6.1 7.4 1.6 5.6 5.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease CDC45 PF02724.9 EEQ33109.1 - 4.3 5.2 6.2 8.8 4.2 4.3 1.4 1 0 0 1 1 1 0 CDC45-like protein ATP-synt PF00231.14 EEQ33110.1 - 5.6e-70 235.9 5.1 6.5e-70 235.7 3.5 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.10 EEQ33111.1 - 1.2e-96 322.1 2.0 1.2e-96 322.1 1.4 3.9 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EEQ33111.1 - 6.6e-86 287.2 3.8 6.6e-86 287.2 2.7 3.3 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EEQ33111.1 - 1e-31 108.4 0.6 1e-31 108.4 0.4 2.3 2 0 0 2 2 2 1 C-terminal topoisomerase domain Epimerase PF01370.16 EEQ33112.1 - 9.6e-19 67.7 0.0 1.5e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ33112.1 - 1.1e-06 27.5 0.0 5.3e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEQ33112.1 - 1.2e-06 27.6 0.0 1.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EEQ33112.1 - 5.5e-06 26.3 0.0 1.2e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEQ33112.1 - 0.00092 19.2 0.0 0.0039 17.2 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EEQ33112.1 - 0.0065 15.4 0.0 0.0098 14.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EEQ33112.1 - 0.028 14.0 0.0 0.081 12.5 0.0 1.9 1 1 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 EEQ33112.1 - 0.082 11.8 0.0 1.5 7.6 0.0 2.3 1 1 0 1 1 1 0 Male sterility protein Ldh_1_N PF00056.18 EEQ33112.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF605 PF04652.11 EEQ33114.1 - 3.2e-98 329.6 13.1 3.7e-98 329.4 9.1 1.0 1 0 0 1 1 1 1 Vta1 like DUF812 PF05667.6 EEQ33114.1 - 0.051 12.0 3.4 0.086 11.3 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NAD_binding_3 PF03447.11 EEQ33114.1 - 0.093 13.1 0.1 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Peptidase_C2 PF00648.16 EEQ33115.1 - 2.7e-24 85.7 0.0 4.3e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EEQ33115.1 - 5.9e-15 55.1 0.0 5.4e-12 45.5 0.0 3.1 2 1 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 EEQ33115.1 - 2e-05 24.3 2.1 4.2e-05 23.3 1.5 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 EEQ33116.1 - 4.6e-58 192.9 1.0 6.5e-22 77.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SNase PF00565.12 EEQ33117.1 - 8.9e-23 80.6 0.0 1.3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ADK PF00406.17 EEQ33118.1 - 8e-35 119.9 0.0 2.2e-19 69.8 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EEQ33118.1 - 1e-15 57.0 0.0 1.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EEQ33118.1 - 2.5e-05 24.5 0.0 0.00023 21.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ33118.1 - 4.3e-05 24.3 0.0 8.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ33118.1 - 0.00034 20.4 0.0 0.0022 17.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EEQ33118.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEQ33118.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEQ33118.1 - 0.13 11.3 0.1 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DNA_primase_lrg PF04104.9 EEQ33119.1 - 2.2e-81 272.9 0.0 3e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sec23_trunk PF04811.10 EEQ33120.1 - 4.4e-78 261.9 0.0 6.5e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEQ33120.1 - 2.4e-33 113.6 0.3 5e-33 112.6 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EEQ33120.1 - 1e-28 99.6 0.0 2.1e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEQ33120.1 - 6e-16 57.7 4.9 1.2e-15 56.7 3.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEQ33120.1 - 2.6e-11 43.0 0.0 6.5e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 EEQ33121.1 - 5.8e-16 57.6 0.2 1.1e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EEQ33121.1 - 8e-10 38.7 0.1 1.3e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain MIP-T3 PF10243.4 EEQ33123.1 - 2 6.7 14.9 2.3 6.5 10.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glyco_transf_41 PF13844.1 EEQ33124.1 - 1.6e-97 326.4 0.3 1.3e-50 171.8 0.0 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_11 PF13414.1 EEQ33124.1 - 1.2e-20 72.9 17.1 3.3e-07 29.8 0.3 4.7 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 EEQ33124.1 - 1.5e-15 56.0 12.9 0.0036 16.8 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ33124.1 - 7.3e-15 53.6 14.6 0.0044 16.8 0.2 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ33124.1 - 7.6e-12 45.5 14.7 5.1e-05 23.8 0.9 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ33124.1 - 1e-11 44.6 10.6 2.2e-05 24.2 0.2 4.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ33124.1 - 4.5e-11 42.3 10.1 0.0038 17.7 0.1 5.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ33124.1 - 9.7e-11 41.0 4.3 0.5 10.6 0.0 5.8 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33124.1 - 8.4e-07 29.2 7.8 0.0029 17.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ33124.1 - 2e-05 24.0 7.4 1 9.3 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EEQ33124.1 - 9.5e-05 22.4 0.5 0.046 13.8 0.0 3.0 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EEQ33124.1 - 0.00011 21.9 15.3 0.15 12.0 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ33124.1 - 0.00023 20.6 10.3 0.0071 16.0 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ33124.1 - 0.0064 16.8 8.8 8.8 7.0 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat BTAD PF03704.12 EEQ33124.1 - 0.0065 16.7 3.6 2.7 8.2 0.0 3.0 3 0 0 3 3 2 2 Bacterial transcriptional activator domain TPR_9 PF13371.1 EEQ33124.1 - 0.93 9.3 6.4 2.2 8.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 EEQ33126.1 - 3.2e-24 84.7 0.6 3.4e-12 46.2 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ33126.1 - 2.2e-19 69.3 6.2 1.9e-13 50.2 0.0 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_23 PF13384.1 EEQ33126.1 - 0.064 12.9 0.2 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF2774 PF11242.3 EEQ33126.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.1 EEQ33126.1 - 0.12 12.4 3.3 0.14 12.2 0.0 2.7 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain ABC_tran PF00005.22 EEQ33128.1 - 1.3e-47 161.5 0.0 7.2e-29 100.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ33128.1 - 1.4e-26 93.4 28.6 3.5e-18 66.0 6.4 3.6 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EEQ33128.1 - 2.2e-10 40.1 2.6 0.00016 20.9 0.2 4.7 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEQ33128.1 - 8.6e-06 25.2 1.1 0.019 14.4 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EEQ33128.1 - 1.7e-05 24.9 1.1 0.01 15.8 0.0 4.0 2 2 1 3 3 3 1 AAA domain AAA_23 PF13476.1 EEQ33128.1 - 3.9e-05 24.0 0.3 0.099 12.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ33128.1 - 6.9e-05 22.3 0.1 0.12 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EEQ33128.1 - 8.4e-05 22.1 0.3 0.55 9.6 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 EEQ33128.1 - 0.00013 21.9 1.8 0.028 14.4 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EEQ33128.1 - 0.00063 18.7 0.2 0.4 9.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 EEQ33128.1 - 0.00068 19.7 0.2 1.6 8.8 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 EEQ33128.1 - 0.00082 20.1 1.6 0.11 13.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ33128.1 - 0.0019 17.6 0.0 0.35 10.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 EEQ33128.1 - 0.0026 17.6 0.1 11 6.0 0.0 4.1 4 0 0 4 4 4 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EEQ33128.1 - 0.0061 16.4 4.7 0.057 13.2 0.2 2.7 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EEQ33128.1 - 0.013 15.8 0.1 0.59 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEQ33128.1 - 0.016 15.0 0.0 6 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EEQ33128.1 - 0.02 14.8 0.4 0.34 10.8 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 EEQ33128.1 - 0.021 13.9 0.0 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MobB PF03205.9 EEQ33128.1 - 0.03 14.0 0.3 0.94 9.1 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EEQ33128.1 - 0.045 13.1 0.0 8.9 5.6 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EEQ33128.1 - 0.092 12.9 0.4 40 4.4 0.0 3.5 3 0 0 3 3 3 0 RNA helicase Miro PF08477.8 EEQ33128.1 - 0.14 12.6 0.1 12 6.4 0.1 2.9 2 0 0 2 2 2 0 Miro-like protein Pox_A32 PF04665.7 EEQ33128.1 - 0.15 11.3 0.4 2.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein Adeno_IVa2 PF02456.10 EEQ33128.1 - 0.15 10.6 0.1 0.82 8.2 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein CbiA PF01656.18 EEQ33128.1 - 0.17 11.3 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 EEQ33128.1 - 0.29 10.7 2.7 17 5.0 0.0 3.3 3 0 0 3 3 3 0 NACHT domain Cu-oxidase_3 PF07732.10 EEQ33129.1 - 2.3e-11 43.4 1.0 1.2e-07 31.4 0.1 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEQ33129.1 - 3.8e-08 32.9 0.0 0.0053 16.2 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EEQ33129.1 - 0.00082 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Copper-bind PF00127.15 EEQ33129.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF2414 PF10309.4 EEQ33130.1 - 3.5e-26 90.6 0.1 5.5e-26 90.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Ribosomal_L29e PF01779.12 EEQ33131.1 - 5.4e-23 80.5 12.5 8.4e-23 79.9 8.7 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family ATP-synt_DE_N PF02823.11 EEQ33132.1 - 5.6e-18 64.4 0.0 7.9e-18 64.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain APH PF01636.18 EEQ33134.1 - 2.5e-40 138.6 0.0 5.8e-40 137.5 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ33134.1 - 2.3e-05 23.7 0.1 4.9e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.9 EEQ33134.1 - 8.9e-05 21.6 0.0 0.00038 19.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEQ33134.1 - 0.0037 16.6 0.0 0.07 12.4 0.0 2.3 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.6 EEQ33134.1 - 0.14 10.7 0.0 0.26 9.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) zf-C2H2_4 PF13894.1 EEQ33136.1 - 3.7e-08 33.1 10.8 0.00084 19.5 2.2 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ33136.1 - 1.9e-06 27.8 9.9 0.0059 16.8 1.4 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ33136.1 - 4.2e-05 23.6 8.0 0.086 13.1 0.1 3.9 3 0 0 3 3 3 3 Zinc-finger double domain PQ-loop PF04193.9 EEQ33137.1 - 3.6e-29 100.0 15.8 1.9e-17 62.5 0.9 2.9 3 0 0 3 3 3 2 PQ loop repeat dUTPase PF00692.14 EEQ33138.1 - 1.7e-44 150.4 0.0 2.1e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 EEQ33138.1 - 0.011 14.1 0.0 0.014 13.7 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Colicin_C PF12106.3 EEQ33138.1 - 0.73 9.4 0.1 0.73 9.4 0.0 2.2 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain Phos_pyr_kin PF08543.7 EEQ33139.1 - 3.7e-11 42.6 0.0 7.2e-11 41.7 0.0 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EEQ33139.1 - 1e-07 31.3 0.0 8.5e-07 28.3 0.0 2.3 2 0 0 2 2 2 1 pfkB family carbohydrate kinase BON PF04972.12 EEQ33139.1 - 0.025 14.3 0.6 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 BON domain Formyl_trans_N PF00551.14 EEQ33140.1 - 5.7e-38 130.2 0.0 6.7e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase 2-ph_phosp PF04029.9 EEQ33140.1 - 0.051 12.5 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 2-phosphosulpholactate phosphatase Erf4 PF10256.4 EEQ33140.1 - 0.057 13.2 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Flagellin_IN PF07196.8 EEQ33140.1 - 0.088 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Flagellin hook IN motif ADIP PF11559.3 EEQ33141.1 - 3.5e-38 130.8 10.1 3.5e-38 130.8 7.0 2.5 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding EcsC PF12787.2 EEQ33141.1 - 0.074 12.4 1.8 0.073 12.4 0.2 1.7 2 0 0 2 2 2 0 EcsC protein family AAA_13 PF13166.1 EEQ33141.1 - 0.23 9.8 10.3 0.036 12.5 2.6 2.0 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.6 EEQ33141.1 - 0.35 9.4 13.8 0.042 12.5 5.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIVA PF05103.8 EEQ33141.1 - 0.62 10.1 11.7 0.088 12.8 3.6 2.8 2 1 1 3 3 3 0 DivIVA protein BLOC1_2 PF10046.4 EEQ33141.1 - 0.89 9.7 12.1 11 6.2 0.4 3.6 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EEQ33141.1 - 1.6 8.8 17.8 0.18 11.9 7.0 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EEQ33141.1 - 2.8 6.9 15.8 0.75 8.7 5.4 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF724 PF05266.9 EEQ33141.1 - 4.7 6.7 12.0 0.34 10.4 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.6 EEQ33141.1 - 4.9 7.6 9.8 0.73 10.2 2.6 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Mod_r PF07200.8 EEQ33141.1 - 7 6.5 16.6 0.26 11.2 2.7 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SAM_2 PF07647.12 EEQ33142.1 - 2.4e-08 33.7 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EEQ33142.1 - 0.00012 22.1 0.5 0.00024 21.2 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DHC_N1 PF08385.7 EEQ33142.1 - 0.37 9.1 6.4 3 6.0 4.5 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 Pyr_redox_2 PF07992.9 EEQ33143.1 - 5.7e-29 101.4 0.0 1.6e-28 99.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ33143.1 - 3.2e-17 62.7 0.7 1.3e-14 54.3 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EEQ33143.1 - 6.6e-14 51.2 0.0 1.9e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EEQ33143.1 - 9.2e-14 51.9 0.0 4e-06 27.0 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ33143.1 - 2e-06 26.9 0.0 0.067 12.0 0.0 2.9 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.1 EEQ33143.1 - 2.1e-05 24.6 0.0 5.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.1 EEQ33143.1 - 6e-05 22.8 0.4 0.24 11.1 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EEQ33143.1 - 0.00056 20.1 0.3 0.36 11.0 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.9 EEQ33143.1 - 0.0064 15.0 0.9 0.61 8.5 0.0 2.7 3 0 0 3 3 3 2 HI0933-like protein DUF1188 PF06690.6 EEQ33143.1 - 0.01 14.9 0.1 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) APH PF01636.18 EEQ33144.1 - 1.5e-05 24.8 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_S3 PF00944.14 EEQ33145.1 - 0.0006 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Alphavirus core protein Trypsin_2 PF13365.1 EEQ33145.1 - 0.003 17.5 0.0 0.01 15.8 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.6 EEQ33145.1 - 0.0037 15.6 0.1 0.0079 14.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family S64 Peptidase_S32 PF05579.8 EEQ33145.1 - 0.025 13.5 0.1 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Arrestin_N PF00339.24 EEQ33147.1 - 0.0021 17.8 0.1 0.0058 16.4 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EEQ33147.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus ACPS PF01648.15 EEQ33149.1 - 3.4e-18 65.5 0.0 4.1e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APH PF01636.18 EEQ33150.1 - 1.2e-15 57.9 0.0 2.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ33150.1 - 0.036 13.6 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ33150.1 - 0.047 12.3 0.0 0.11 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Use1 PF09753.4 EEQ33150.1 - 0.073 12.5 0.1 0.32 10.4 0.0 1.9 1 1 1 2 2 2 0 Membrane fusion protein Use1 EcKinase PF02958.15 EEQ33150.1 - 0.087 11.9 0.0 0.35 9.9 0.0 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.17 EEQ33150.1 - 0.12 11.7 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 RIO1 family HD PF01966.17 EEQ33151.1 - 0.00099 19.1 0.6 0.02 14.8 0.0 2.6 2 1 0 2 2 2 1 HD domain HflK_N PF12221.3 EEQ33151.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Coatomer_WDAD PF04053.9 EEQ33152.1 - 0.058 12.1 0.1 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region MIF4G PF02854.14 EEQ33153.1 - 1.4e-26 93.2 0.1 2.8e-26 92.2 0.1 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EEQ33153.1 - 1.2e-24 86.2 0.1 4.1e-24 84.4 0.0 2.0 2 0 0 2 2 2 1 MA3 domain NOA36 PF06524.7 EEQ33153.1 - 6.5 5.9 8.7 10 5.2 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.17 EEQ33155.1 - 2.6e-17 62.1 0.0 2.3e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ33155.1 - 6.5e-12 45.2 0.0 1.9e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEQ33155.1 - 9.4e-05 22.0 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 RRM_5 PF13893.1 EEQ33155.1 - 0.00054 19.7 0.0 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L7Ae PF01248.21 EEQ33158.1 - 1.1e-25 88.9 0.0 1.3e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family COesterase PF00135.23 EEQ33159.1 - 5.8e-66 223.3 0.0 7.1e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ33159.1 - 3.3e-07 30.0 0.0 5.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ33159.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ33159.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Afi1 PF07792.7 EEQ33160.1 - 6.3e-45 152.7 0.3 2.4e-44 150.8 0.2 2.0 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EEQ33160.1 - 4.3e-37 126.2 0.0 6.9e-37 125.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EEQ33160.1 - 1.2e-07 30.5 0.0 0.061 11.8 0.0 3.5 2 1 1 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.4 EEQ33160.1 - 0.072 12.3 0.0 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) GSAP-16 PF14959.1 EEQ33160.1 - 0.073 12.8 0.3 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term EF-hand_6 PF13405.1 EEQ33161.1 - 2.1e-13 48.9 2.2 1.2e-05 24.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EEQ33161.1 - 2e-12 45.4 1.7 4.5e-05 22.4 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EEQ33161.1 - 8.8e-12 44.9 5.5 5e-09 36.1 0.7 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EEQ33161.1 - 5e-08 31.9 4.9 0.00061 19.0 0.5 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EEQ33161.1 - 2.6e-06 26.9 0.4 0.053 13.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EEQ33161.1 - 0.0028 17.5 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain RabGAP-TBC PF00566.13 EEQ33162.1 - 8.3e-31 107.1 0.0 7.3e-30 104.0 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 EEQ33164.1 - 3.9e-26 89.9 8.1 6e-08 32.2 0.1 6.2 5 0 0 5 5 5 5 WD domain, G-beta repeat SET PF00856.23 EEQ33164.1 - 9.2e-06 26.0 6.0 0.019 15.2 0.0 4.8 5 0 0 5 5 5 2 SET domain zf-MYND PF01753.13 EEQ33164.1 - 0.3 10.9 5.1 0.73 9.7 3.6 1.7 1 0 0 1 1 1 0 MYND finger DUF605 PF04652.11 EEQ33164.1 - 2.5 7.3 6.2 7.3 5.8 4.3 1.7 1 0 0 1 1 1 0 Vta1 like Glucosamine_iso PF01182.15 EEQ33166.1 - 1e-57 195.1 0.0 1.2e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DNA_mis_repair PF01119.14 EEQ33168.1 - 1.7e-11 43.6 0.0 4.9e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EEQ33168.1 - 3.5e-10 39.5 0.0 6.9e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EEQ33168.1 - 3.9e-09 36.2 0.4 7.7e-09 35.3 0.3 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NT5C PF06941.7 EEQ33168.1 - 0.1 12.0 0.1 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) APH PF01636.18 EEQ33169.1 - 1.6e-14 54.2 0.0 6.2e-14 52.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ33169.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA-synt_1c PF00749.16 EEQ33170.1 - 2e-93 312.5 0.0 2.9e-93 311.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEQ33170.1 - 3.2e-36 124.6 0.5 4.9e-36 124.0 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EEQ33170.1 - 2.2e-07 31.2 0.0 5.7e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ33170.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEQ33170.1 - 0.025 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1682 PF07946.9 EEQ33171.1 - 0.14 10.9 12.2 0.2 10.4 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) F-box PF00646.28 EEQ33172.1 - 1.6e-07 30.7 0.0 4.8e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ33172.1 - 7.5e-06 25.5 0.1 1.8e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.12 EEQ33172.1 - 0.043 13.7 5.0 2.4 8.2 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.1 EEQ33172.1 - 1.1 9.5 4.5 26 5.2 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat IDO PF01231.13 EEQ33173.1 - 6.4e-42 143.4 0.0 1e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Glyco_hydro_16 PF00722.16 EEQ33174.1 - 2.7e-07 30.0 0.4 4.1e-07 29.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF4328 PF14219.1 EEQ33174.1 - 0.048 12.9 0.5 0.097 11.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) CLTH PF10607.4 EEQ33175.1 - 7.1e-31 106.8 0.0 1.5e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EEQ33175.1 - 1.9e-08 34.4 0.0 3.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EEQ33175.1 - 0.0012 18.4 0.5 0.0041 16.8 0.1 2.2 2 0 0 2 2 2 1 LisH INO80_Ies4 PF08193.6 EEQ33176.1 - 1.2e-52 179.0 25.1 1.6e-52 178.6 17.4 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 RNA_pol_Rpc4 PF05132.9 EEQ33176.1 - 8.9 6.3 8.0 1.9 8.4 1.9 2.2 2 1 0 2 2 2 0 RNA polymerase III RPC4 DnaJ PF00226.26 EEQ33177.1 - 8e-13 47.9 0.0 1.7e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Rab5ip PF07019.7 EEQ33179.1 - 9.3e-09 35.3 9.0 1.7e-07 31.2 6.2 2.1 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DSBA PF01323.15 EEQ33180.1 - 2.7e-31 108.6 0.0 3.2e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EEQ33180.1 - 0.0022 18.0 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EEQ33180.1 - 0.025 14.7 0.0 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain MFS_1 PF07690.11 EEQ33181.1 - 7e-25 87.4 64.3 3.1e-23 82.0 11.8 3.7 1 1 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 EEQ33181.1 - 7.9e-09 34.2 13.9 1.3e-08 33.5 9.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sulfate_transp PF00916.15 EEQ33182.1 - 2.1e-71 240.1 11.1 4.4e-71 239.1 7.7 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EEQ33182.1 - 2.2e-31 107.3 3.3 2.2e-31 107.3 2.3 3.3 3 1 1 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EEQ33182.1 - 3e-05 23.4 0.0 5.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain DnaJ PF00226.26 EEQ33184.1 - 2.6e-25 87.9 2.6 4.3e-25 87.2 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EEQ33184.1 - 1.1e-22 79.7 0.1 3.3e-20 71.7 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EEQ33184.1 - 5.6e-13 48.7 17.9 1e-12 47.9 12.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EEQ33184.1 - 0.15 11.7 9.5 0.25 11.0 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family URO-D PF01208.12 EEQ33185.1 - 1.8e-122 408.5 0.0 2.1e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) WD40 PF00400.27 EEQ33186.1 - 6e-09 35.4 0.6 0.00034 20.3 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Ribosomal_L10 PF00466.15 EEQ33187.1 - 2.1e-26 91.7 0.0 4.3e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EEQ33187.1 - 1.3e-10 41.5 0.1 8.3e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein PDEase_I PF00233.14 EEQ33188.1 - 6e-29 101.4 0.5 1.3e-26 93.8 0.5 3.0 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Rdx PF10262.4 EEQ33189.1 - 3.7e-28 97.3 0.0 5.1e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.17 EEQ33190.1 - 1.9e-21 75.5 0.0 2.2e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.22 EEQ33191.1 - 4.1e-12 46.3 0.4 1.8e-10 41.0 0.0 3.0 2 0 0 2 2 2 1 PCI domain CENP-Q PF13094.1 EEQ33192.1 - 7.9 6.4 13.4 7.6 6.5 6.7 2.4 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Acetyltransf_1 PF00583.19 EEQ33193.1 - 1.3e-13 50.7 0.1 1.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEQ33193.1 - 6.4e-06 25.8 0.0 9.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ33193.1 - 9.4e-06 25.7 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ33193.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ33193.1 - 0.00057 19.7 0.1 0.00077 19.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ33193.1 - 0.0013 18.5 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EEQ33194.1 - 5.8e-23 81.1 55.0 1e-17 63.8 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APOC4 PF15119.1 EEQ33194.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein C4 Pkinase PF00069.20 EEQ33195.1 - 9.7e-21 74.0 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33195.1 - 1.8e-14 53.4 0.0 2.5e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ33195.1 - 7.4e-05 21.8 0.0 0.0001 21.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ33195.1 - 0.00052 19.8 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ33195.1 - 0.027 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family RNA_pol_Rpb6 PF01192.17 EEQ33196.1 - 5.6e-24 83.6 0.2 8e-24 83.1 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2_4 PF13894.1 EEQ33197.1 - 1.3e-23 81.4 48.9 0.0019 18.3 0.0 10.7 10 1 1 11 11 11 7 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ33197.1 - 1.1e-22 78.9 59.3 0.00025 21.2 0.4 11.5 11 1 1 12 12 12 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ33197.1 - 9.8e-15 54.0 54.0 0.0015 18.6 0.3 11.1 11 0 0 11 11 11 8 Zinc-finger double domain GAGA PF09237.6 EEQ33197.1 - 0.00013 21.4 0.4 0.00013 21.4 0.3 2.1 2 0 0 2 2 2 1 GAGA factor zf-C2H2_jaz PF12171.3 EEQ33197.1 - 0.25 11.5 20.8 6.4 7.0 0.0 7.5 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.7 EEQ33197.1 - 0.44 10.8 14.4 1.3 9.2 0.3 4.7 3 1 1 4 4 4 0 CHORD ANATO PF01821.13 EEQ33197.1 - 1.2 9.2 10.3 7.2 6.8 0.1 4.9 5 0 0 5 5 5 0 Anaphylotoxin-like domain DUF4557 PF15101.1 EEQ33198.1 - 1.7 8.4 10.3 4.9 6.9 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) COPIIcoated_ERV PF07970.7 EEQ33199.1 - 4.4e-67 225.9 0.0 1.1e-44 152.7 0.0 2.7 2 1 1 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EEQ33199.1 - 2.2e-34 117.2 0.0 4.6e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) LRR_4 PF12799.2 EEQ33200.1 - 8.8e-10 37.9 6.2 2.9e-06 26.7 0.4 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) TAP_C PF03943.8 EEQ33200.1 - 2.3e-07 30.1 0.4 5.1e-07 28.9 0.3 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_8 PF13855.1 EEQ33200.1 - 7.5e-05 22.4 0.3 0.00015 21.3 0.2 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.1 EEQ33200.1 - 0.00046 19.8 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.15 EEQ33200.1 - 0.00075 19.8 0.0 0.0024 18.2 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_1 PF00560.28 EEQ33200.1 - 0.0022 17.7 0.5 0.95 9.7 0.1 3.7 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.1 EEQ33200.1 - 0.15 12.2 0.5 3.5 7.9 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 EEQ33200.1 - 0.17 12.2 0.8 11 6.7 0.0 3.7 3 0 0 3 3 3 0 Leucine rich repeat Vps53_N PF04100.7 EEQ33201.1 - 6e-104 347.8 8.0 6e-104 347.8 5.5 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 EEQ33201.1 - 5.1e-07 28.8 8.2 5.1e-07 28.8 5.7 2.0 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EEQ33201.1 - 0.00035 20.4 1.9 0.0018 18.1 1.3 2.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 EEQ33201.1 - 0.011 14.4 9.1 0.02 13.6 5.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Cbl_N PF02262.11 EEQ33201.1 - 0.039 13.6 2.0 4.7 6.9 0.0 3.3 3 1 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 Snapin_Pallidin PF14712.1 EEQ33201.1 - 5.9 7.2 14.7 0.36 11.1 1.6 4.4 3 1 0 4 4 4 0 Snapin/Pallidin DEAD PF00270.24 EEQ33202.1 - 9.8e-19 67.4 0.2 6.8e-18 64.7 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EEQ33202.1 - 2.6e-07 30.6 0.0 1.7e-06 28.0 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ33202.1 - 1.2e-05 25.0 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EEQ33202.1 - 0.00014 21.9 0.0 0.00041 20.4 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF1524 PF07510.6 EEQ33205.1 - 1.2e-13 51.0 0.0 1.6e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EEQ33205.1 - 0.0055 16.3 0.2 0.018 14.6 0.1 1.9 1 1 0 1 1 1 1 HNH endonuclease RPW8 PF05659.6 EEQ33206.1 - 0.047 13.2 0.2 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Pkinase PF00069.20 EEQ33208.1 - 9.7e-14 51.1 0.0 2.1e-13 50.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33208.1 - 3e-06 26.5 0.0 1.5e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ33208.1 - 0.038 13.7 0.1 0.3 10.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.27 EEQ33209.1 - 1.1e-27 94.7 3.1 9.2e-07 28.5 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Gmad1 PF10647.4 EEQ33209.1 - 0.0014 18.0 0.0 0.0054 16.1 0.0 1.8 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EEQ33209.1 - 0.014 13.5 0.4 0.33 9.0 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EEQ33209.1 - 0.016 14.6 0.2 0.075 12.4 0.1 1.9 1 1 1 2 2 2 0 PQQ-like domain FTHFS PF01268.14 EEQ33210.1 - 9.7e-252 835.8 0.0 1.5e-251 835.2 0.0 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EEQ33210.1 - 2.4e-66 221.7 1.3 2.4e-66 221.7 0.9 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EEQ33210.1 - 3.3e-34 117.4 0.1 8.4e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 EEQ33210.1 - 0.12 12.1 0.8 2.9 7.7 0.6 2.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Iso_dh PF00180.15 EEQ33211.1 - 1.5e-55 188.5 0.0 5.8e-49 166.8 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase MBF1 PF08523.5 EEQ33212.1 - 2.6e-28 97.8 0.6 4.8e-28 96.9 0.4 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EEQ33212.1 - 7.5e-12 44.9 0.1 1.5e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EEQ33212.1 - 6.8e-08 32.6 0.1 1.5e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EEQ33212.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MFS_1 PF07690.11 EEQ33213.1 - 0.0082 14.8 35.5 0.11 11.1 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SH3_1 PF00018.23 EEQ33214.1 - 1.8e-14 52.8 0.0 2.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ33214.1 - 6.7e-13 47.9 0.0 3e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EEQ33214.1 - 8.9e-09 34.7 0.0 1.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Glyco_tranf_2_3 PF13641.1 EEQ33215.1 - 4.8e-25 88.6 0.0 6.7e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EEQ33215.1 - 6.1e-08 32.5 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EEQ33215.1 - 3.3e-07 29.7 0.0 0.00044 19.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EEQ33215.1 - 0.004 16.8 14.3 0.074 12.7 9.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 ATP12 PF07542.6 EEQ33218.1 - 2.2e-33 114.7 0.2 3.6e-33 114.1 0.1 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Oxysterol_BP PF01237.13 EEQ33219.1 - 2.6e-133 443.9 0.0 6.4e-133 442.6 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EEQ33219.1 - 1.8e-22 79.4 0.1 1.2e-12 48.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ33219.1 - 3.7e-19 68.3 0.2 1.9e-11 43.7 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EEQ33219.1 - 7.6e-17 60.1 0.2 1e-06 28.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EEQ33219.1 - 6.3e-14 50.7 0.0 1e-05 25.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EEQ33219.1 - 2.3e-11 43.8 0.1 5e-05 23.7 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PH PF00169.24 EEQ33219.1 - 4e-10 39.8 0.1 9.9e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EEQ33219.1 - 1.8e-09 37.8 0.3 9.2e-09 35.5 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EEQ33219.1 - 4.4e-07 29.8 0.8 1.1e-06 28.5 0.5 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain LLC1 PF14945.1 EEQ33219.1 - 0.0014 18.9 0.6 0.0014 18.9 0.5 3.3 4 0 0 4 4 4 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Shigella_OspC PF06128.6 EEQ33219.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Shigella flexneri OspC protein zf-Mss51 PF13824.1 EEQ33220.1 - 1.2e-28 98.7 6.5 1.2e-28 98.7 4.5 2.1 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EEQ33220.1 - 0.0057 16.4 2.4 0.0057 16.4 1.6 2.0 2 0 0 2 2 2 1 MYND finger GFA PF04828.9 EEQ33220.1 - 0.093 12.6 1.7 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme ADH_zinc_N PF00107.21 EEQ33221.1 - 2.5e-30 104.7 0.5 4.1e-30 103.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ33221.1 - 5.8e-09 36.9 0.0 1.3e-08 35.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ33221.1 - 2.9e-08 33.4 0.0 1.3e-07 31.2 0.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EEQ33221.1 - 0.049 13.6 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pep_deformylase PF01327.16 EEQ33221.1 - 0.12 11.8 0.1 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase Clr5 PF14420.1 EEQ33222.1 - 1.3e-06 28.2 0.2 2.2e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Clr5 domain ISG65-75 PF11727.3 EEQ33222.1 - 1.6 7.6 6.3 10 5.0 1.3 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF99 PF01949.11 EEQ33223.1 - 0.09 11.8 0.3 0.11 11.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF99 Pro-MCH PF05824.7 EEQ33224.1 - 0.085 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) DIM1 PF02966.11 EEQ33224.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 SNF2_N PF00176.18 EEQ33226.1 - 9.3e-73 244.6 1.2 1.5e-72 243.9 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ33226.1 - 5.8e-15 54.9 0.0 1.5e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ33226.1 - 5.4e-07 29.6 0.0 1.7e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ33226.1 - 1.7e-05 24.3 0.1 7.3e-05 22.3 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase HSA PF07529.8 EEQ33226.1 - 3.7e-05 23.4 7.0 0.0002 21.1 4.8 2.2 1 0 0 1 1 1 1 HSA TM231 PF10149.4 EEQ33226.1 - 0.014 14.3 0.1 0.029 13.3 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 231 NDUF_B8 PF05821.6 EEQ33227.1 - 8.1e-05 22.3 0.0 8.9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.4 EEQ33228.1 - 2e-25 89.1 0.0 6.6e-25 87.4 0.0 2.0 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EEQ33228.1 - 1.3e-13 50.5 0.0 3.1e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain Ribonuc_L-PSP PF01042.16 EEQ33229.1 - 7.9e-41 138.6 0.1 8.8e-41 138.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP BID PF06393.6 EEQ33229.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 BH3 interacting domain (BID) NmrA PF05368.8 EEQ33230.1 - 7.4e-12 45.0 0.0 9.4e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ33230.1 - 5.8e-08 32.9 0.0 8.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ33230.1 - 0.00016 21.1 0.0 0.007 15.8 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EEQ33230.1 - 0.00047 19.2 0.1 0.00071 18.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EEQ33230.1 - 0.00078 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain CoA_binding_3 PF13727.1 EEQ33230.1 - 0.011 15.5 0.1 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain Macro_2 PF14519.1 EEQ33230.1 - 0.023 13.8 0.4 0.56 9.2 0.0 2.2 2 0 0 2 2 2 0 Macro-like domain GARS_N PF02844.10 EEQ33230.1 - 0.025 15.0 0.1 0.042 14.3 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain NAD_binding_4 PF07993.7 EEQ33230.1 - 0.036 13.0 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 EEQ33230.1 - 0.039 13.8 0.2 0.23 11.3 0.1 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EEQ33230.1 - 0.067 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lumazine_bd_2 PF12893.2 EEQ33231.1 - 8.2e-25 87.6 0.0 9.4e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Putative lumazine-binding Lumazine_bd PF12870.2 EEQ33231.1 - 0.002 18.1 0.0 0.017 15.1 0.0 2.1 1 1 0 1 1 1 1 Lumazine-binding domain Catalase PF00199.14 EEQ33232.1 - 6.4e-134 446.4 0.0 8.5e-134 446.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEQ33232.1 - 1.7e-07 30.9 0.2 5.2e-07 29.4 0.1 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive adh_short PF00106.20 EEQ33233.1 - 1.1e-23 84.0 0.3 1.7e-23 83.3 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ33233.1 - 9.6e-18 64.8 0.0 1.2e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ33233.1 - 1.5e-12 47.5 0.5 2.7e-12 46.7 0.3 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ33233.1 - 2.4e-05 23.9 0.0 6.3e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEQ33233.1 - 0.002 17.0 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4332 PF14229.1 EEQ33233.1 - 0.0026 17.7 0.0 0.0088 16.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4332) NAD_binding_10 PF13460.1 EEQ33233.1 - 0.043 13.8 0.4 4.8 7.1 0.2 2.4 2 1 0 2 2 2 0 NADH(P)-binding Methyltransf_33 PF10017.4 EEQ33234.1 - 8.2e-28 96.8 0.0 1.4e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EEQ33234.1 - 0.045 14.1 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_4 PF01565.18 EEQ33235.1 - 3.1e-19 68.8 1.0 6.6e-19 67.7 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ33235.1 - 3.6e-10 39.6 0.2 9e-10 38.3 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Trp_DMAT PF11991.3 EEQ33236.1 - 3e-124 414.8 0.0 3.6e-124 414.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Tax PF02959.11 EEQ33236.1 - 0.063 12.7 0.0 1.9 7.8 0.0 2.4 3 0 0 3 3 3 0 HTLV Tax ApbE PF02424.10 EEQ33238.1 - 0.036 13.3 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 ApbE family HD PF01966.17 EEQ33239.1 - 0.042 13.8 0.0 0.081 12.9 0.0 1.5 1 1 0 1 1 1 0 HD domain Pribosyltran PF00156.22 EEQ33241.1 - 7.4e-16 58.0 0.0 1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEQ33241.1 - 0.0044 16.2 0.0 0.0059 15.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.15 EEQ33242.1 - 1.1e-132 442.9 0.0 1.4e-132 442.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MiaE PF06175.6 EEQ33242.1 - 0.29 10.4 0.0 0.47 9.7 0.0 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) WD40 PF00400.27 EEQ33244.1 - 2.9e-45 150.5 15.4 1.1e-07 31.4 0.1 7.3 6 1 1 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 EEQ33244.1 - 0.016 14.7 0.6 4.5 6.6 0.0 3.0 3 1 0 3 3 3 0 PQQ-like domain TRAPP PF04051.11 EEQ33245.1 - 5.5e-37 126.6 0.0 6.7e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LisH PF08513.6 EEQ33247.1 - 0.0001 21.9 0.1 0.00019 21.0 0.1 1.5 1 0 0 1 1 1 1 LisH RRP7 PF12923.2 EEQ33250.1 - 9.7e-29 100.0 10.3 9.7e-29 100.0 7.1 2.6 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EEQ33250.1 - 0.034 13.7 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3377 PF11857.3 EEQ33250.1 - 2.9 7.5 7.4 1.4 8.6 0.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Rad51 PF08423.6 EEQ33251.1 - 4.7e-126 418.9 0.0 6.2e-126 418.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EEQ33251.1 - 1.6e-13 50.4 0.1 2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EEQ33251.1 - 7.9e-10 38.4 0.0 1.1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEQ33251.1 - 1.4e-08 34.1 0.0 2.6e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 EEQ33251.1 - 1.3e-05 25.2 2.5 1.7e-05 24.8 0.2 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain zf-CCHC PF00098.18 EEQ33252.1 - 1.4e-32 110.0 28.6 1.8e-07 30.7 0.6 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 EEQ33252.1 - 2.7e-06 27.0 16.7 0.04 13.6 0.3 4.2 3 1 1 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EEQ33252.1 - 1.9e-05 24.2 20.8 0.25 11.0 0.2 5.0 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.1 EEQ33252.1 - 0.0011 18.4 23.4 0.046 13.2 0.3 5.3 4 1 1 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.1 EEQ33252.1 - 2.8 7.7 22.3 0.17 11.5 1.0 4.3 5 0 0 5 5 5 0 Zinc knuckle UDPGP PF01704.13 EEQ33253.1 - 1.8e-56 191.4 0.0 2.5e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EEQ33253.1 - 0.012 15.7 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fer4_20 PF14691.1 EEQ33253.1 - 0.044 13.4 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pro_isomerase PF00160.16 EEQ33254.1 - 2e-32 112.5 0.0 3.2e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EEQ33254.1 - 9.4e-16 57.2 0.6 1.9e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ33254.1 - 1.8e-12 47.0 0.0 5.2e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ33254.1 - 4.7e-10 39.1 0.7 1.5e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ33254.1 - 0.17 11.6 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif VGCC_beta4Aa_N PF12052.3 EEQ33254.1 - 2.8 7.8 6.7 7 6.6 4.7 1.7 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Zn_clus PF00172.13 EEQ33255.1 - 9.6e-09 35.0 6.9 2.3e-08 33.7 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.14 EEQ33256.1 - 7.3e-32 109.0 0.1 1.1e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.4 EEQ33257.1 - 1.8e-20 73.1 0.0 2.7e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EEQ33257.1 - 1.3e-05 25.7 0.0 2.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEQ33257.1 - 6e-05 22.3 0.0 8.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEQ33257.1 - 0.00014 21.3 0.1 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 EEQ33257.1 - 0.0041 16.6 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_23 PF13489.1 EEQ33257.1 - 0.0062 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ33257.1 - 0.0066 16.0 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EEQ33257.1 - 0.015 15.7 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ33257.1 - 0.018 15.4 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EEQ33257.1 - 0.022 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.9 EEQ33257.1 - 0.023 13.8 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_31 PF13847.1 EEQ33257.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EEQ33257.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_26 PF13659.1 EEQ33257.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pro-kuma_activ PF09286.6 EEQ33258.1 - 6.9e-38 129.9 0.0 2.4e-37 128.1 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEQ33258.1 - 3.3e-10 39.6 0.1 1.7e-09 37.2 0.0 2.0 2 1 0 2 2 2 1 Subtilase family DUF2306 PF10067.4 EEQ33259.1 - 1.7e-09 37.7 8.7 1.7e-09 37.7 6.0 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) SAC3_GANP PF03399.11 EEQ33261.1 - 2.8e-25 89.0 0.0 4e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEQ33261.1 - 1.8e-21 76.4 0.0 3.3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 WD40 PF00400.27 EEQ33262.1 - 0.0016 18.2 0.0 0.084 12.7 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEQ33262.1 - 0.17 11.3 0.3 22 4.6 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Vps51 PF08700.6 EEQ33263.1 - 7.9e-25 86.5 0.0 1.3e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EEQ33263.1 - 0.0013 18.6 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 EEQ33263.1 - 0.0095 14.4 0.1 0.014 13.9 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Fes1 PF08609.5 EEQ33263.1 - 0.033 14.6 0.0 0.39 11.2 0.0 2.2 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 GAF PF01590.21 EEQ33263.1 - 0.092 12.8 0.4 0.2 11.7 0.1 1.6 2 0 0 2 2 2 0 GAF domain DUF1767 PF08585.7 EEQ33264.1 - 2.5e-17 62.9 0.1 3.8e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 EEQ33265.1 - 1.1e-41 140.2 46.0 1e-06 28.2 0.0 13.4 11 2 4 15 15 15 9 TPR repeat TPR_16 PF13432.1 EEQ33265.1 - 6.3e-25 87.2 45.4 0.0002 21.9 0.6 13.5 12 2 2 14 14 14 8 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ33265.1 - 1.7e-24 83.9 15.3 0.019 15.1 0.0 13.8 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33265.1 - 1.2e-22 79.9 27.3 3.2e-08 33.7 0.9 10.9 9 2 2 11 11 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ33265.1 - 1.8e-21 74.2 58.0 0.0063 16.3 0.2 16.2 18 0 0 18 18 17 8 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ33265.1 - 3.1e-20 70.8 43.2 0.014 15.0 0.1 13.7 16 0 0 16 16 13 7 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ33265.1 - 1.8e-19 68.4 36.4 0.042 14.4 0.0 16.7 14 5 6 20 20 17 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ33265.1 - 2e-16 59.7 47.4 5e-06 26.3 0.6 12.1 8 1 4 12 12 12 5 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ33265.1 - 1e-14 53.0 33.5 0.0019 17.8 0.3 12.2 13 1 1 14 14 13 6 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ33265.1 - 1e-06 28.0 27.2 8.9e-05 22.0 0.0 11.0 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ33265.1 - 5.2e-05 23.4 36.2 0.059 13.8 0.3 13.1 15 0 0 15 15 13 2 Tetratricopeptide repeat TPR_5 PF12688.2 EEQ33265.1 - 9.1e-05 22.4 0.8 0.074 13.0 0.1 3.3 2 0 0 2 2 2 1 Tetratrico peptide repeat Apc3 PF12895.2 EEQ33265.1 - 0.0037 17.3 31.3 0.012 15.7 0.3 7.6 7 1 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.5 EEQ33265.1 - 0.0074 15.1 2.3 15 4.2 0.0 4.5 4 1 1 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.4 EEQ33265.1 - 0.0075 15.7 4.2 0.16 11.4 0.2 2.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.1 EEQ33265.1 - 0.014 15.2 10.4 12 5.8 0.2 6.5 8 1 0 8 8 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ33265.1 - 0.077 12.9 0.0 0.077 12.9 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.12 EEQ33265.1 - 1.4 9.1 16.7 0.82 9.9 0.1 5.2 4 2 1 6 6 5 0 Bacterial transcriptional activator domain Apc5 PF12862.2 EEQ33265.1 - 5.7 6.8 15.9 1.3 8.9 0.1 6.2 6 2 1 7 7 7 0 Anaphase-promoting complex subunit 5 Cellulase PF00150.13 EEQ33266.1 - 3.9e-08 32.8 4.2 1.5e-06 27.6 0.8 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Xpo1 PF08389.7 EEQ33267.1 - 8.5e-13 48.4 5.5 3.2e-10 40.0 1.4 4.0 3 1 0 3 3 3 1 Exportin 1-like protein Drf_GBD PF06371.8 EEQ33267.1 - 0.007 15.7 0.2 0.014 14.7 0.1 1.5 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain IBN_N PF03810.14 EEQ33267.1 - 0.014 15.2 1.3 0.23 11.4 0.0 3.3 3 0 0 3 3 3 0 Importin-beta N-terminal domain GRIM-19 PF06212.7 EEQ33268.1 - 3.8e-22 78.3 0.1 8e-22 77.3 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 EEQ33269.1 - 5e-33 114.2 0.1 8.3e-32 110.2 0.1 2.1 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VID27 PF08553.5 EEQ33270.1 - 0 1136.4 0.1 0 1136.3 0.1 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Usp PF00582.21 EEQ33270.1 - 0.72 10.0 7.6 19 5.4 0.0 2.7 2 0 0 2 2 2 0 Universal stress protein family PBP_sp32 PF07222.7 EEQ33270.1 - 3 6.9 8.5 6.3 5.9 5.9 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.9 EEQ33270.1 - 5.5 4.9 10.5 8.4 4.2 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein TLD PF07534.11 EEQ33271.1 - 1.5e-21 76.8 0.0 1.8e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 TLD Adaptin_N PF01602.15 EEQ33272.1 - 1.3e-126 422.9 8.4 2.6e-105 352.7 6.6 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.2 EEQ33272.1 - 1.2e-29 103.4 4.7 3.2e-27 95.5 0.1 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEQ33272.1 - 1.9e-17 63.3 2.7 2.7e-06 27.5 0.0 5.4 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.17 EEQ33272.1 - 2.7e-11 42.5 0.1 0.016 15.2 0.0 5.1 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EEQ33272.1 - 0.0031 17.9 6.1 1.1 9.8 0.0 5.7 6 1 0 6 6 6 1 HEAT-like repeat CLASP_N PF12348.3 EEQ33272.1 - 0.0062 15.9 0.8 1.6 8.0 0.0 4.0 2 1 2 4 4 4 1 CLASP N terminal Cohesin_HEAT PF12765.2 EEQ33272.1 - 0.077 12.9 0.1 12 5.9 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_60s PF00428.14 EEQ33272.1 - 3.1 8.2 9.3 2.3 8.6 4.0 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DEK_C PF08766.6 EEQ33273.1 - 0.00017 21.2 0.4 0.00044 19.9 0.3 1.7 1 0 0 1 1 1 1 DEK C terminal domain POPLD PF08170.7 EEQ33273.1 - 0.31 10.9 0.1 0.31 10.9 0.1 2.0 2 1 0 2 2 2 0 POPLD (NUC188) domain Evr1_Alr PF04777.8 EEQ33274.1 - 8.5e-27 92.9 3.4 9.7e-27 92.7 1.4 1.7 2 0 0 2 2 2 1 Erv1 / Alr family Sporozoite_P67 PF05642.6 EEQ33274.1 - 0.36 8.6 4.2 0.37 8.5 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Coatomer_WDAD PF04053.9 EEQ33275.1 - 5.8e-145 483.4 0.1 8.8e-145 482.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EEQ33275.1 - 4.7e-96 321.9 0.0 7e-96 321.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EEQ33275.1 - 2e-48 160.5 16.2 9.8e-09 34.7 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EEQ33275.1 - 0.0015 16.7 5.2 0.24 9.4 0.0 3.6 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EEQ33275.1 - 0.0016 18.0 0.2 0.093 12.3 0.0 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Phytase-like PF13449.1 EEQ33277.1 - 5.6e-29 101.4 0.3 1.2e-28 100.4 0.0 1.6 2 1 0 2 2 2 1 Esterase-like activity of phytase MMPL PF03176.10 EEQ33277.1 - 0.22 10.1 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 MMPL family Clr5 PF14420.1 EEQ33279.1 - 1.3e-20 73.0 2.2 1.3e-20 73.0 1.5 2.2 2 0 0 2 2 2 1 Clr5 domain TAXi_C PF14541.1 EEQ33279.1 - 0.18 11.3 0.0 0.46 10.0 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Sensor PF13796.1 EEQ33279.1 - 0.92 9.0 3.8 0.67 9.5 1.3 1.7 2 0 0 2 2 2 0 Putative sensor Het-C PF07217.6 EEQ33280.1 - 7.4e-267 886.4 0.0 9.6e-267 886.0 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Gly-zipper_OmpA PF13436.1 EEQ33280.1 - 2.7 7.6 10.6 0.75 9.4 3.1 2.6 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF2828 PF11443.3 EEQ33281.1 - 6.9e-166 552.5 0.1 8.1e-166 552.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) FAD-oxidase_C PF02913.14 EEQ33282.1 - 2.9e-57 193.8 0.1 5.5e-57 192.9 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EEQ33282.1 - 4.2e-36 123.4 0.0 6.8e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_2 PF00703.16 EEQ33283.1 - 1.8e-09 38.0 0.0 3.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EEQ33283.1 - 2.4e-09 36.9 0.0 6.6e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EEQ33283.1 - 5.5e-07 28.7 0.0 1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain ADH_N PF08240.7 EEQ33284.1 - 8e-33 112.4 1.8 3.7e-32 110.3 0.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ33284.1 - 7.6e-25 86.9 0.1 1.5e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EEQ33284.1 - 0.0012 19.3 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EEQ33284.1 - 0.0025 18.6 0.1 0.0043 17.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EEQ33284.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 EEQ33284.1 - 0.064 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ras PF00071.17 EEQ33285.1 - 1e-41 142.0 0.0 1.4e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ33285.1 - 5.4e-15 55.9 0.0 8.7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ33285.1 - 4.7e-12 45.4 0.0 2.5e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ33285.1 - 2.1e-05 24.0 0.0 8.3e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEQ33285.1 - 6.4e-05 22.2 0.0 9.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ33285.1 - 0.00075 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EEQ33285.1 - 0.002 17.6 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EEQ33285.1 - 0.0031 17.6 0.0 0.0079 16.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EEQ33285.1 - 0.0045 16.8 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEQ33285.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EEQ33285.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EEQ33285.1 - 0.027 14.1 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain SRPRB PF09439.5 EEQ33285.1 - 0.029 13.5 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EEQ33285.1 - 0.059 13.0 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 EEQ33285.1 - 0.061 13.3 0.0 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EEQ33285.1 - 0.077 12.5 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 EEQ33285.1 - 0.15 11.5 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain bZIP_1 PF00170.16 EEQ33286.1 - 1.3e-06 28.2 6.8 2.9e-06 27.1 4.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor SF-assemblin PF06705.6 EEQ33286.1 - 0.0057 15.8 0.4 0.0092 15.1 0.3 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin bZIP_2 PF07716.10 EEQ33286.1 - 2.5 7.9 8.6 4.6 7.1 6.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper AIM24 PF01987.12 EEQ33289.1 - 5.5e-57 192.6 0.3 6.5e-57 192.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.12 EEQ33290.1 - 2.6e-44 149.9 0.1 4e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EEQ33290.1 - 0.076 13.3 0.7 0.25 11.6 0.5 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 EEQ33290.1 - 1.1 9.4 7.0 0.96 9.6 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain RR_TM4-6 PF06459.7 EEQ33290.1 - 2.9 7.6 11.4 4 7.2 7.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2201_N PF13203.1 EEQ33290.1 - 3.8 6.6 8.0 5.5 6.0 5.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain bZIP_1 PF00170.16 EEQ33295.1 - 1.5e-06 28.0 13.4 1.2e-05 25.2 9.4 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ33295.1 - 0.00069 19.3 14.2 0.00069 19.3 9.9 1.8 1 1 1 2 2 2 1 Basic region leucine zipper DUF1635 PF07795.6 EEQ33295.1 - 1.3 8.3 7.1 0.63 9.3 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) Auts2 PF15336.1 EEQ33295.1 - 3.1 7.7 17.9 5.7 6.8 1.1 3.1 2 1 1 3 3 3 0 Autism susceptibility gene 2 protein RRM_1 PF00076.17 EEQ33296.1 - 7.6e-25 86.3 0.1 1e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ33296.1 - 1.2e-17 63.6 0.0 1.5e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ33296.1 - 1.2e-11 44.2 0.0 1.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEQ33296.1 - 0.04 13.7 0.1 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif ChaC PF04752.7 EEQ33297.1 - 6.1e-31 107.7 0.0 9e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.27 EEQ33298.1 - 8e-20 68.5 7.6 6.9e-07 28.1 0.1 4.7 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EEQ33298.1 - 2e-18 65.7 8.4 4.2e-10 39.0 0.0 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EEQ33298.1 - 2.5e-17 61.1 5.6 0.00085 19.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EEQ33298.1 - 6.8e-17 61.3 4.8 7.8e-07 29.1 2.9 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EEQ33298.1 - 1.3e-12 46.4 9.0 0.00013 21.1 0.3 4.7 4 1 0 4 4 4 3 EF hand G6PD_C PF02781.11 EEQ33299.1 - 9.1e-135 448.1 0.0 1.3e-134 447.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EEQ33299.1 - 1.6e-64 217.5 0.0 3e-64 216.6 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.11 EEQ33300.1 - 1.5e-30 106.1 53.6 5.9e-29 100.8 37.0 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ33300.1 - 2.8e-09 35.7 15.8 6.1e-07 28.0 5.7 2.7 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ33300.1 - 8.7e-09 34.4 8.9 8.7e-09 34.4 6.1 4.1 1 1 3 5 5 5 1 Sugar (and other) transporter CBS PF00571.23 EEQ33301.1 - 0.0002 21.0 0.0 0.25 11.1 0.0 3.2 1 1 1 2 2 2 1 CBS domain ADH_zinc_N_2 PF13602.1 EEQ33302.1 - 0.0062 17.4 0.0 0.11 13.4 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase SnoaL_2 PF12680.2 EEQ33303.1 - 0.083 13.2 0.1 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like domain Mito_carr PF00153.22 EEQ33304.1 - 1.1e-50 169.2 9.5 9.4e-21 73.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EEQ33305.1 - 5.1e-48 159.3 28.6 5.6e-12 45.0 0.1 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEQ33305.1 - 0.00015 21.2 0.1 0.3 10.6 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EEQ33305.1 - 0.079 11.7 0.2 0.14 10.9 0.2 1.3 1 0 0 1 1 1 0 Coatomer WD associated region FAD_binding_4 PF01565.18 EEQ33306.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ICE2 PF08426.5 EEQ33307.1 - 3.1e-119 398.2 15.2 3.8e-119 397.9 10.6 1.0 1 0 0 1 1 1 1 ICE2 DUF1440 PF07274.7 EEQ33307.1 - 2.2 8.3 7.8 0.13 12.2 0.4 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1440) Endosulfine PF04667.12 EEQ33308.1 - 6.8e-10 38.7 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.8 EEQ33309.1 - 9.6e-44 149.1 0.0 1.1e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.17 EEQ33310.1 - 4.8e-113 378.4 0.0 6.6e-113 378.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 EEQ33310.1 - 0.02 14.6 0.0 0.064 13.0 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ33310.1 - 0.033 14.0 0.0 0.17 11.7 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1772 PF08592.6 EEQ33310.1 - 0.1 12.3 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Pro_isomerase PF00160.16 EEQ33311.1 - 3.1e-44 150.9 0.4 3.9e-44 150.5 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD COesterase PF00135.23 EEQ33312.1 - 3.4e-104 349.4 0.0 4.6e-104 349.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ33312.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ33312.1 - 0.0014 17.8 0.0 0.0032 16.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Fungal_trans_2 PF11951.3 EEQ33313.1 - 7.8e-06 24.7 0.6 6.5e-05 21.7 0.4 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.24 EEQ33314.1 - 2.4e-46 157.3 0.0 7.7e-45 152.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ33314.1 - 4e-28 97.0 0.1 7.5e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ33314.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEQ33314.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EEQ33314.1 - 0.33 9.2 0.0 0.57 8.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) INSIG PF07281.7 EEQ33316.1 - 4e-47 160.0 5.5 9.2e-47 158.8 3.8 1.5 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Clathrin PF00637.15 EEQ33317.1 - 8.2e-199 651.1 34.1 1.3e-34 118.8 1.1 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EEQ33317.1 - 7.3e-30 101.1 8.8 5.4e-05 23.2 0.0 7.8 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 EEQ33317.1 - 1.6e-29 101.6 0.2 6.1e-29 99.7 0.1 2.1 1 0 0 1 1 1 1 Clathrin-H-link TPR_14 PF13428.1 EEQ33317.1 - 9.9e-05 22.6 8.1 3.2 8.6 0.2 8.3 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33317.1 - 0.00043 20.5 0.8 40 4.6 0.0 5.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ33317.1 - 0.0078 15.9 6.6 30 4.7 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Clathrin-link PF09268.5 EEQ33317.1 - 0.01 14.8 0.2 0.023 13.7 0.1 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Ank_3 PF13606.1 EEQ33317.1 - 0.067 13.4 0.0 1.7 9.1 0.0 3.5 2 0 0 2 2 2 0 Ankyrin repeat CPSase_L_D2 PF02786.12 EEQ33318.1 - 2.8e-80 268.5 0.1 4.9e-80 267.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EEQ33318.1 - 3.6e-66 222.3 0.0 6e-66 221.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EEQ33318.1 - 5.8e-36 122.9 0.0 1.2e-35 121.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EEQ33318.1 - 4.7e-31 106.9 0.0 1.6e-30 105.2 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EEQ33318.1 - 6.4e-25 88.1 0.0 1.4e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 EEQ33318.1 - 3.2e-17 61.9 4.5 3.5e-17 61.7 2.0 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EEQ33318.1 - 5.8e-17 62.0 0.1 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEQ33318.1 - 3.4e-16 58.9 0.0 1.3e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EEQ33318.1 - 2.6e-10 39.7 2.8 3.7e-06 26.4 0.1 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EEQ33318.1 - 1.8e-09 37.3 0.0 3.5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EEQ33318.1 - 8.8e-07 28.5 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EEQ33318.1 - 3.3e-06 26.5 0.0 7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EEQ33318.1 - 0.00013 21.9 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EEQ33318.1 - 0.0017 17.5 0.0 1.3 8.0 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EEQ33318.1 - 0.0037 17.5 0.2 0.066 13.5 0.1 3.0 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 EEQ33318.1 - 0.014 14.7 0.0 0.065 12.5 0.1 2.0 2 0 0 2 2 2 0 HlyD family secretion protein DUF2118 PF09891.4 EEQ33318.1 - 0.035 13.8 0.1 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Rieske PF00355.21 EEQ33318.1 - 0.095 12.2 0.1 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain DLIC PF05783.6 EEQ33319.1 - 1 7.9 3.8 1.2 7.6 2.6 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ribosomal_L5_C PF00673.16 EEQ33320.1 - 1.4e-22 79.2 0.0 1.9e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EEQ33320.1 - 2e-21 75.5 0.1 7.2e-21 73.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 EEQ33321.1 - 1.7e-18 65.8 0.0 2.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 EEQ33322.1 - 2e-26 92.2 0.1 4.2e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0041) Aa_trans PF01490.13 EEQ33323.1 - 2.4e-86 289.8 34.4 2.8e-86 289.5 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 EEQ33324.1 - 3e-48 164.3 32.8 4.1e-48 163.9 22.7 1.2 1 0 0 1 1 1 1 Amino acid permease Nop14 PF04147.7 EEQ33324.1 - 1.2 6.9 3.9 1.6 6.5 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family GHMP_kinases_N PF00288.21 EEQ33325.1 - 1.7e-18 66.4 0.1 9.2e-18 64.0 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEQ33325.1 - 3.7e-08 33.4 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EEQ33325.1 - 0.0097 15.1 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.17 EEQ33326.1 - 1.9e-36 121.8 13.9 1.6e-09 36.6 0.3 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.1 EEQ33326.1 - 8.1e-06 26.3 4.6 0.0012 19.4 0.8 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33326.1 - 0.079 13.3 4.3 3.8 7.9 1.8 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ33326.1 - 0.1 13.2 3.0 0.22 12.2 0.4 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ33326.1 - 0.11 12.1 1.4 0.44 10.2 0.5 2.4 2 1 0 2 2 2 0 TPR repeat PALP PF00291.20 EEQ33327.1 - 1.1e-52 179.1 0.1 2.4e-52 178.0 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PEP_mutase PF13714.1 EEQ33327.1 - 0.077 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Sporozoite_P67 PF05642.6 EEQ33328.1 - 0.079 10.8 0.0 0.084 10.7 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen tRNA-synt_1g PF09334.6 EEQ33329.1 - 1.9e-116 388.9 0.1 2.9e-116 388.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEQ33329.1 - 7.8e-23 80.3 0.3 7.1e-12 44.1 0.0 3.8 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EEQ33329.1 - 2.2e-09 36.8 0.1 5.2e-05 22.5 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EEQ33329.1 - 0.011 15.4 0.0 0.029 14.1 0.0 1.6 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA NTF2 PF02136.15 EEQ33330.1 - 9.6e-10 38.8 0.5 2.6e-08 34.2 0.3 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EEQ33330.1 - 0.00016 21.5 0.1 0.0003 20.5 0.1 1.4 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Ribosomal_L38e PF01781.13 EEQ33331.1 - 6.8e-32 109.0 1.5 8.1e-32 108.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF1470 PF07336.6 EEQ33332.1 - 0.084 13.2 0.3 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) Ish1 PF10281.4 EEQ33332.1 - 0.12 12.4 0.1 0.46 10.6 0.0 1.9 1 1 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Acetyltransf_3 PF13302.1 EEQ33333.1 - 3.9e-31 108.1 0.0 7.4e-31 107.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ33333.1 - 2.3e-06 27.5 0.4 0.065 13.1 0.0 3.0 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ33333.1 - 0.00058 19.5 0.2 0.017 14.8 0.0 2.2 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 EEQ33333.1 - 0.0028 17.6 0.0 0.0097 15.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Serglycin PF04360.7 EEQ33333.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Serglycin Acetyltransf_1 PF00583.19 EEQ33333.1 - 0.029 14.3 0.1 0.91 9.5 0.1 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family DNA_pol_E_B PF04042.11 EEQ33334.1 - 9.2e-49 165.5 0.0 2.2e-48 164.2 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B NMO PF03060.10 EEQ33335.1 - 5.3e-73 246.0 0.4 6.1e-73 245.8 0.3 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEQ33335.1 - 4.5e-05 22.4 0.0 0.022 13.6 0.1 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEQ33335.1 - 0.0033 16.3 2.1 0.0049 15.7 1.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ATP_synt_I PF03899.10 EEQ33335.1 - 0.11 12.6 0.3 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 ATP synthase I chain DUF627 PF04781.7 EEQ33335.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Taxilin PF09728.4 EEQ33336.1 - 5.7e-91 304.8 44.1 6.8e-91 304.5 30.6 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Fic_N PF13784.1 EEQ33336.1 - 0.25 11.2 0.0 0.25 11.2 0.0 2.8 3 0 0 3 3 3 0 Fic/DOC family N-terminal DUF4201 PF13870.1 EEQ33336.1 - 0.38 10.1 36.3 0.12 11.8 12.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) DUF3675 PF12428.3 EEQ33336.1 - 0.6 10.3 5.0 5.2 7.3 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) DUF725 PF05267.7 EEQ33336.1 - 0.82 9.5 8.1 0.047 13.5 1.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF725) COG2 PF06148.6 EEQ33336.1 - 1.1 9.1 14.6 4.3 7.2 0.4 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.3 EEQ33336.1 - 3.4 6.8 27.1 3.3 6.9 1.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.3 EEQ33336.1 - 3.4 7.4 41.0 0.48 10.1 7.8 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FliD_N PF02465.13 EEQ33336.1 - 3.7 7.9 16.8 2.5 8.5 0.8 3.4 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CENP-F_leu_zip PF10473.4 EEQ33336.1 - 5.3 6.8 42.9 12 5.7 7.9 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 EEQ33336.1 - 7 6.4 22.2 0.38 10.4 2.7 3.1 1 1 2 4 4 4 0 Laminin Domain II G10 PF01125.12 EEQ33336.1 - 7.1 6.1 9.3 0.69 9.4 1.8 2.4 2 0 0 2 2 2 0 G10 protein M16C_assoc PF08367.6 EEQ33337.1 - 6.1e-56 189.0 0.4 1.3e-55 187.9 0.3 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EEQ33337.1 - 1.5e-25 89.9 0.0 4.3e-14 52.6 0.0 2.8 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEQ33337.1 - 4.7e-10 39.3 0.1 5.1e-09 36.0 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Methyltransf_11 PF08241.7 EEQ33338.1 - 6.2e-16 58.6 0.1 9.7e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ33338.1 - 1.4e-12 47.5 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ33338.1 - 2.6e-12 46.5 0.0 3.4e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ33338.1 - 3e-12 46.8 0.0 4.7e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ33338.1 - 1.8e-11 44.6 0.0 2.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ33338.1 - 1.2e-09 38.4 0.1 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEQ33338.1 - 1.5e-08 34.0 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EEQ33338.1 - 3.3e-08 33.5 0.1 6.9e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ33338.1 - 4.1e-08 32.7 0.0 6e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EEQ33338.1 - 2.3e-07 29.8 0.0 3.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 EEQ33338.1 - 4.7e-07 29.1 0.0 6.9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EEQ33338.1 - 1.2e-06 27.7 0.0 1.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EEQ33338.1 - 2.1e-05 24.1 0.0 3.1e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 EEQ33338.1 - 3.9e-05 23.1 0.0 5.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EEQ33338.1 - 0.0057 16.3 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EEQ33338.1 - 0.011 14.5 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.8 EEQ33338.1 - 0.017 14.2 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EEQ33338.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.7 EEQ33338.1 - 0.034 13.5 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.6 EEQ33338.1 - 0.076 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Pox_MCEL PF03291.11 EEQ33338.1 - 0.21 10.4 0.0 0.39 9.5 0.0 1.4 1 1 1 2 2 2 0 mRNA capping enzyme DUF202 PF02656.10 EEQ33339.1 - 3.7e-19 68.7 4.1 3.9e-19 68.6 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DJ-1_PfpI PF01965.19 EEQ33339.1 - 0.12 11.8 0.2 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Cation_efflux PF01545.16 EEQ33340.1 - 5.8e-82 274.9 2.0 1.3e-81 273.8 1.4 1.5 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 EEQ33340.1 - 0.0045 16.0 9.4 0.011 14.7 6.5 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Pkinase PF00069.20 EEQ33341.1 - 1.1e-22 80.3 0.0 3.7e-22 78.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33341.1 - 7.1e-08 31.8 0.0 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ33341.1 - 0.15 10.9 0.0 0.44 9.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Metallophos PF00149.23 EEQ33342.1 - 1.1e-08 34.6 4.4 1.8e-06 27.4 3.1 3.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Tyrosinase PF00264.15 EEQ33343.1 - 7.8e-51 173.3 5.7 7.8e-51 173.3 4.0 1.9 2 0 0 2 2 2 1 Common central domain of tyrosinase Fungal_trans PF04082.13 EEQ33344.1 - 1.1e-17 63.8 1.8 1.8e-16 59.8 1.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain RGCC PF15151.1 EEQ33344.1 - 1.2 9.5 3.2 0.63 10.4 0.2 2.0 2 0 0 2 2 2 0 Response gene to complement 32 protein family Zn_clus PF00172.13 EEQ33344.1 - 1.9 8.4 10.8 4.5 7.2 7.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S8e PF01201.17 EEQ33345.1 - 5.4e-28 97.7 1.1 1e-27 96.9 0.8 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Pkinase PF00069.20 EEQ33347.1 - 1.4e-48 165.3 0.0 2.1e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33347.1 - 5.1e-18 65.0 0.0 7.9e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ33347.1 - 9.7e-05 21.7 0.2 0.00028 20.3 0.1 1.8 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.1 EEQ33347.1 - 0.00036 19.6 0.0 0.00057 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ33347.1 - 0.00099 18.8 0.0 0.44 10.2 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEQ33347.1 - 0.076 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PWI PF01480.12 EEQ33348.1 - 4.8e-29 100.2 0.1 7.3e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 PWI domain FAA_hydrolase PF01557.13 EEQ33351.1 - 5.9e-52 176.2 0.0 7.1e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Apolipoprotein PF01442.13 EEQ33352.1 - 0.035 13.6 3.4 0.063 12.7 2.3 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EEQ33352.1 - 0.046 13.5 1.5 0.098 12.4 1.0 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 EEQ33352.1 - 0.11 12.7 2.5 0.23 11.8 1.3 1.8 1 1 0 1 1 1 0 Snapin/Pallidin DUF883 PF05957.8 EEQ33352.1 - 0.21 12.0 4.3 0.49 10.8 2.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HTH_1 PF00126.22 EEQ33352.1 - 0.23 11.2 2.6 0.17 11.6 0.3 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family OmpH PF03938.9 EEQ33352.1 - 1.1 9.2 5.3 1.8 8.4 3.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cortex-I_coil PF09304.5 EEQ33352.1 - 2.4 8.2 8.7 5.4 7.0 5.7 1.9 1 1 0 1 1 1 0 Cortexillin I, coiled coil DEAD PF00270.24 EEQ33353.1 - 1.9e-43 147.8 1.4 3.7e-43 146.9 0.7 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ33353.1 - 1.3e-27 95.4 0.2 3.7e-27 93.9 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ33353.1 - 0.00078 19.3 0.1 0.002 17.9 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EEQ33353.1 - 0.0011 18.6 0.2 0.0031 17.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.1 EEQ33353.1 - 0.0097 15.0 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EEQ33353.1 - 0.013 15.2 0.1 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EEQ33353.1 - 0.017 15.2 0.1 0.059 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EEQ33353.1 - 0.046 12.5 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain tRNA-synt_1b PF00579.20 EEQ33353.1 - 0.083 12.0 0.0 0.46 9.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.9 EEQ33353.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.9 EEQ33353.1 - 0.11 12.2 0.1 0.66 9.7 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Cupin_8 PF13621.1 EEQ33354.1 - 2.8e-17 63.0 0.0 2.6e-16 59.8 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EEQ33354.1 - 3e-09 37.1 0.5 4.4e-08 33.3 0.1 2.8 2 1 0 2 2 2 1 JmjC domain, hydroxylase F-box-like PF12937.2 EEQ33354.1 - 0.00018 21.1 0.1 0.00041 20.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ33354.1 - 0.069 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 F-box domain Cupin_4 PF08007.7 EEQ33354.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Ctr PF04145.10 EEQ33355.1 - 2e-26 92.7 9.0 8.4e-26 90.7 6.2 1.7 1 1 0 1 1 1 1 Ctr copper transporter family NuA4 PF09340.5 EEQ33356.1 - 2.8e-27 94.1 0.1 4.9e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Glyco_hydro_38 PF01074.17 EEQ33357.1 - 1.5e-90 303.2 0.6 3.4e-90 302.0 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EEQ33357.1 - 8.6e-68 229.1 0.0 2.2e-67 227.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EEQ33357.1 - 2.4e-24 85.3 0.0 4.6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain NUDIX PF00293.23 EEQ33359.1 - 7.3e-11 41.8 0.0 3.8e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain LETM1 PF07766.8 EEQ33360.1 - 1.4e-91 306.2 0.1 5.8e-90 300.9 0.1 2.4 1 1 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EEQ33360.1 - 7.9e-05 22.0 0.0 0.3 10.6 0.0 3.3 3 0 0 3 3 3 2 SAP domain DUF2838 PF10998.3 EEQ33361.1 - 3.5e-41 139.5 10.8 3.5e-41 139.5 7.5 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) NFRKB_winged PF14465.1 EEQ33361.1 - 0.011 15.5 0.1 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 NFRKB Winged Helix-like OmpH PF03938.9 EEQ33361.1 - 3.3 7.6 6.6 0.75 9.7 1.6 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF349 PF03993.7 EEQ33361.1 - 5.3 7.2 8.4 2.2 8.5 2.9 2.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) SMC_N PF02463.14 EEQ33362.1 - 1.4e-59 200.9 0.1 3.8e-37 127.6 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEQ33362.1 - 1.2e-30 105.9 2.4 2.2e-30 105.0 0.0 2.8 3 1 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEQ33362.1 - 1.1e-11 45.2 12.7 1.6e-06 28.2 0.2 4.3 3 1 1 5 5 5 2 AAA domain AAA_23 PF13476.1 EEQ33362.1 - 1.2e-11 45.2 15.4 1.2e-11 45.2 10.7 6.5 2 2 2 5 5 3 1 AAA domain AAA_29 PF13555.1 EEQ33362.1 - 2.6e-08 33.2 0.0 5.8e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EEQ33362.1 - 0.0011 18.8 0.0 0.0065 16.3 0.0 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF4200 PF13863.1 EEQ33362.1 - 0.0018 18.2 6.3 0.0018 18.2 4.4 9.0 4 3 6 10 10 7 3 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 EEQ33362.1 - 0.0058 16.3 0.6 0.0058 16.3 0.4 8.2 4 3 2 7 7 7 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EEQ33362.1 - 0.068 12.3 33.6 0.47 9.5 3.5 4.8 3 2 0 5 5 5 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EEQ33362.1 - 1.6 8.5 55.7 0.14 11.9 3.4 8.3 4 2 4 9 9 9 0 Protein of unknown function (DUF1664) YqjK PF13997.1 EEQ33362.1 - 2.4 8.4 4.8 45 4.3 0.2 3.3 2 0 0 2 2 2 0 YqjK-like protein Tropomyosin PF00261.15 EEQ33362.1 - 9.4 5.2 117.6 0.64 9.0 23.1 6.5 4 2 2 6 6 6 0 Tropomyosin E3_binding PF02817.12 EEQ33364.1 - 9e-09 34.8 0.0 1.4e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 e3 binding domain ABC_tran PF00005.22 EEQ33365.1 - 3.8e-72 240.9 0.0 4.3e-35 121.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ33365.1 - 3.7e-70 236.4 39.0 3.7e-36 124.9 9.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EEQ33365.1 - 2.3e-13 49.9 1.7 0.0028 16.9 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ33365.1 - 1.7e-11 44.6 0.0 0.029 14.3 0.0 4.5 2 2 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EEQ33365.1 - 5.5e-11 41.7 0.8 0.00025 19.7 0.1 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EEQ33365.1 - 2.5e-10 39.7 1.9 0.00032 20.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ33365.1 - 2.3e-09 37.5 3.2 1.3e-05 25.3 0.1 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EEQ33365.1 - 3.3e-09 37.6 0.0 0.00048 20.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEQ33365.1 - 2.9e-07 29.7 0.1 0.0043 16.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEQ33365.1 - 1.4e-06 28.4 0.2 0.1 12.7 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EEQ33365.1 - 1.8e-05 24.3 1.3 0.16 11.7 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain AAA_18 PF13238.1 EEQ33365.1 - 1.9e-05 24.9 0.0 0.063 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ33365.1 - 0.00014 21.3 0.0 0.41 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EEQ33365.1 - 0.00016 21.3 0.0 0.26 10.9 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EEQ33365.1 - 0.00018 21.0 0.3 0.51 9.7 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_23 PF13476.1 EEQ33365.1 - 0.00019 21.8 1.0 0.38 11.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EEQ33365.1 - 0.0002 21.2 0.3 0.22 11.2 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_33 PF13671.1 EEQ33365.1 - 0.0002 21.2 0.0 0.74 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EEQ33365.1 - 0.0004 20.0 0.1 1.8 8.1 0.0 3.3 4 0 0 4 4 3 2 AAA domain Zeta_toxin PF06414.7 EEQ33365.1 - 0.00087 18.4 0.2 1.7 7.6 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin G-alpha PF00503.15 EEQ33365.1 - 0.0013 17.5 0.0 0.15 10.7 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit MobB PF03205.9 EEQ33365.1 - 0.0013 18.4 0.1 2.1 8.0 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 EEQ33365.1 - 0.0014 18.2 0.0 1.3 8.6 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA PF00004.24 EEQ33365.1 - 0.0015 18.7 0.6 0.85 9.8 0.0 4.2 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 EEQ33365.1 - 0.0019 17.8 0.0 1.9 7.9 0.0 2.7 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein SbcCD_C PF13558.1 EEQ33365.1 - 0.0019 18.0 1.6 2.9 7.8 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EEQ33365.1 - 0.0074 16.2 0.3 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EEQ33365.1 - 0.0076 15.7 0.0 4.2 6.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 EEQ33365.1 - 0.012 15.5 0.0 4.5 7.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EEQ33365.1 - 0.013 14.9 0.6 3 7.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EEQ33365.1 - 0.016 15.1 0.4 3.8 7.4 0.1 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 EEQ33365.1 - 0.02 14.2 0.2 0.58 9.5 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EEQ33365.1 - 0.025 14.3 0.7 25 4.5 0.0 3.3 3 0 0 3 3 3 0 NTPase RNA_helicase PF00910.17 EEQ33365.1 - 0.051 13.7 0.0 11 6.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 EEQ33365.1 - 0.065 13.7 0.2 11 6.5 0.0 3.3 3 0 0 3 3 2 0 Miro-like protein AAA_24 PF13479.1 EEQ33365.1 - 0.1 12.1 0.0 18 4.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AMP-binding PF00501.23 EEQ33366.1 - 6e-240 795.7 0.0 1.6e-84 283.7 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EEQ33366.1 - 1.1e-143 477.5 0.0 1.9e-37 128.7 0.0 7.0 5 1 1 6 6 6 6 Condensation domain PP-binding PF00550.20 EEQ33366.1 - 2.4e-25 88.5 0.1 2.9e-11 43.4 0.0 4.1 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ33366.1 - 1.5e-14 54.7 0.0 1.5e-06 29.0 0.0 3.7 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EEQ33366.1 - 0.0049 17.1 0.3 0.082 13.2 0.0 3.0 4 0 0 4 4 4 1 HxxPF-repeated domain Transferase PF02458.10 EEQ33366.1 - 0.0082 14.6 0.0 0.18 10.1 0.0 2.7 3 0 0 3 3 3 1 Transferase family DUF1324 PF07038.6 EEQ33366.1 - 0.048 13.6 2.1 0.12 12.3 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) WD40 PF00400.27 EEQ33367.1 - 3.4e-37 124.9 4.7 1.1e-07 31.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEQ33367.1 - 2.4e-08 33.8 0.1 0.0038 16.9 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A ATPgrasp_ST PF14397.1 EEQ33367.1 - 0.065 12.3 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Peptidase_M18 PF02127.10 EEQ33368.1 - 1.8e-161 537.4 0.0 2.1e-161 537.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) MFS_1 PF07690.11 EEQ33369.1 - 1.4e-46 158.8 47.9 1.8e-36 125.5 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ33369.1 - 5.4e-44 150.5 13.7 6.8e-44 150.1 9.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EEQ33369.1 - 0.00048 18.3 0.0 0.0011 17.1 0.0 1.5 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.3 EEQ33369.1 - 0.0006 18.4 22.8 0.00087 17.8 4.8 2.4 1 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EEQ33369.1 - 0.01 15.6 0.7 2.8 7.8 0.0 2.8 2 0 0 2 2 2 0 MFS_1 like family Sigma70_r4 PF04545.11 EEQ33369.1 - 0.013 14.7 0.8 6.5 6.1 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_38 PF13936.1 EEQ33369.1 - 0.028 13.9 0.7 0.54 9.8 0.7 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain PsbH PF00737.15 EEQ33369.1 - 1.3 8.6 6.4 0.5 9.9 1.5 2.6 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Hydrolase_6 PF13344.1 EEQ33370.1 - 1.8e-29 101.6 0.0 3.5e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ33370.1 - 6.7e-13 49.5 0.0 1.1e-12 48.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ33370.1 - 2.2e-12 46.5 0.1 5.1e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EEQ33370.1 - 2e-06 28.1 0.0 0.00019 21.7 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EEQ33370.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.2 EEQ33370.1 - 0.18 11.9 1.0 4.5 7.3 0.7 2.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1746 PF08508.5 EEQ33372.1 - 2e-42 143.7 1.1 3e-42 143.2 0.8 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.18 EEQ33373.1 - 3.7e-75 251.5 0.0 4.6e-75 251.2 0.0 1.0 1 0 0 1 1 1 1 Clp protease DHDPS PF00701.17 EEQ33373.1 - 0.013 14.0 0.0 0.022 13.3 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family AAA PF00004.24 EEQ33374.1 - 4e-12 46.4 0.0 1.8e-11 44.3 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EEQ33374.1 - 8.6e-12 45.0 0.0 1.2e-06 28.3 0.0 2.8 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.10 EEQ33374.1 - 5.6e-11 41.8 0.1 1.1e-07 30.9 0.0 2.3 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EEQ33374.1 - 2.9e-10 40.0 0.0 6.6e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_11 PF13086.1 EEQ33374.1 - 2e-05 24.3 0.0 3.6e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ33374.1 - 6.7e-05 22.0 0.0 0.00014 21.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EEQ33374.1 - 0.0005 20.2 0.1 0.021 14.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ33374.1 - 0.00077 19.4 0.2 0.042 13.8 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 EEQ33374.1 - 0.0021 17.2 0.0 0.067 12.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EEQ33374.1 - 0.0025 16.8 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EEQ33374.1 - 0.0061 16.0 0.2 0.02 14.3 0.1 1.9 1 1 0 1 1 1 1 FtsK/SpoIIIE family DUF2075 PF09848.4 EEQ33374.1 - 0.0062 15.5 0.0 0.018 14.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EEQ33374.1 - 0.0067 16.1 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 EEQ33374.1 - 0.0094 15.5 1.6 0.027 14.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain Rsbr_N PF08678.5 EEQ33374.1 - 0.017 14.9 0.2 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 Rsbr N terminal MFS_1 PF07690.11 EEQ33375.1 - 9.8e-43 146.2 50.7 9.8e-43 146.2 35.2 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ33375.1 - 2.4e-15 55.7 15.9 4.3e-15 54.9 11.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ33375.1 - 9.4e-12 44.2 33.2 1.8e-11 43.2 10.3 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3925 PF13063.1 EEQ33375.1 - 0.26 11.3 3.8 3.9 7.5 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3925) Sec20 PF03908.8 EEQ33376.1 - 3.2e-16 58.7 2.8 4e-16 58.5 1.2 1.7 2 0 0 2 2 2 1 Sec20 MRP_L53 PF10780.4 EEQ33377.1 - 2.7e-14 52.8 0.2 3.8e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.14 EEQ33378.1 - 1.7e-13 50.2 0.4 1.4e-09 37.5 0.0 2.2 1 1 1 2 2 2 2 Inorganic pyrophosphatase Dus PF01207.12 EEQ33379.1 - 1.1e-42 146.0 0.0 2e-42 145.1 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_M28 PF04389.12 EEQ33380.1 - 7.9e-34 116.9 0.0 1.2e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EEQ33380.1 - 8.6e-17 60.6 0.2 8.6e-17 60.6 0.1 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M42 PF05343.9 EEQ33380.1 - 0.018 13.8 0.0 0.1 11.3 0.0 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase SNF2_N PF00176.18 EEQ33382.1 - 1.4e-58 198.0 0.1 2.1e-58 197.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ33382.1 - 1.5e-15 56.7 0.0 4.7e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ33382.1 - 6.5e-08 32.6 0.1 1.9e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ33382.1 - 8.7e-07 28.5 0.0 2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_2 PF12796.2 EEQ33384.1 - 6e-135 439.9 16.1 2.2e-21 75.9 0.1 10.4 3 2 5 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ33384.1 - 3.2e-117 376.9 43.5 1e-07 31.4 0.0 23.3 22 1 1 23 23 23 20 Ankyrin repeat Ank_3 PF13606.1 EEQ33384.1 - 6.2e-104 329.3 22.2 1.8e-05 24.5 0.0 23.1 23 0 0 23 23 23 18 Ankyrin repeat Ank_4 PF13637.1 EEQ33384.1 - 5.4e-90 294.3 19.9 3.9e-11 43.1 0.0 17.4 9 3 8 18 18 18 15 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ33384.1 - 2.5e-65 215.0 39.4 3.9e-05 23.7 0.1 19.6 10 5 10 20 20 20 16 Ankyrin repeats (many copies) Clr5 PF14420.1 EEQ33384.1 - 1.1e-12 47.6 1.5 2.4e-12 46.5 1.0 1.6 1 0 0 1 1 1 1 Clr5 domain DUF3447 PF11929.3 EEQ33384.1 - 2.4e-05 24.0 0.0 4.9 7.0 0.0 6.2 5 2 2 7 7 7 1 Domain of unknown function (DUF3447) Shigella_OspC PF06128.6 EEQ33384.1 - 3.3e-05 23.5 8.0 12 5.3 0.2 7.9 5 3 5 11 11 11 2 Shigella flexneri OspC protein Reductase_C PF14759.1 EEQ33384.1 - 0.16 12.2 4.4 12 6.2 0.0 5.7 7 0 0 7 7 7 0 Reductase C-terminal DUF1656 PF07869.7 EEQ33386.1 - 0.025 14.3 4.1 0.16 11.7 0.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1656) Glyco_hydro_18 PF00704.23 EEQ33387.1 - 2.1e-36 126.1 6.3 1e-35 123.8 4.4 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEQ33387.1 - 5.6e-10 38.9 1.1 2.2e-05 24.2 0.0 3.5 4 0 0 4 4 4 2 LysM domain Chitin_bind_1 PF00187.14 EEQ33387.1 - 4.8e-05 23.2 3.7 4.8e-05 23.2 2.5 3.0 2 0 0 2 2 2 1 Chitin recognition protein DUF3142 PF11340.3 EEQ33387.1 - 0.025 14.2 0.0 0.062 12.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3142) LysM PF01476.15 EEQ33389.1 - 1.5e-09 37.5 0.3 2.9e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 LysM domain TetR_C_8 PF14278.1 EEQ33389.1 - 0.22 11.9 4.6 0.61 10.5 3.2 1.7 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region GSu_C4xC__C2xCH PF09698.5 EEQ33389.1 - 6.6 7.0 8.0 5.5 7.2 3.5 2.3 2 1 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) APH PF01636.18 EEQ33390.1 - 2.2e-05 24.3 0.0 0.00013 21.7 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Lipoprotein_7 PF01540.11 EEQ33391.1 - 0.0083 15.2 0.1 0.01 14.9 0.1 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein GreA_GreB_N PF03449.10 EEQ33391.1 - 1.8 8.6 4.5 4 7.5 0.0 2.7 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal TRAM_LAG1_CLN8 PF03798.11 EEQ33392.1 - 1.2e-32 113.1 14.9 2.4e-32 112.0 10.3 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EEQ33392.1 - 2e-23 81.6 0.2 2e-23 81.6 0.1 2.2 2 1 0 2 2 2 1 TRAM1-like protein YkuD PF03734.9 EEQ33392.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Hira PF07569.6 EEQ33393.1 - 6.1e-78 260.9 0.0 1.4e-77 259.7 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 EEQ33393.1 - 8.5e-42 139.5 17.7 1.5e-07 31.0 0.0 8.9 8 0 0 8 8 8 8 WD domain, G-beta repeat HIRA_B PF09453.5 EEQ33393.1 - 1.8e-09 36.9 0.1 4.9e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EEQ33393.1 - 6.6e-06 25.6 1.1 1.6 8.4 0.0 4.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EEQ33393.1 - 0.013 13.3 0.0 0.034 11.9 0.0 1.7 1 0 0 1 1 1 0 IKI3 family TFIIIC_delta PF12657.2 EEQ33393.1 - 0.021 14.5 0.3 3.1 7.4 0.0 3.2 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term YchF-GTPase_C PF06071.8 EEQ33394.1 - 2.1e-32 110.7 0.2 4.1e-32 109.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EEQ33394.1 - 2e-13 50.2 0.0 5e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ33394.1 - 0.00089 18.5 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EEQ33394.1 - 0.0027 17.4 0.0 0.0095 15.7 0.0 1.9 1 1 0 1 1 1 1 TGS domain MobB PF03205.9 EEQ33394.1 - 0.12 12.0 0.6 3.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PUA PF01472.15 EEQ33395.1 - 4e-13 48.8 0.2 5.9e-13 48.3 0.2 1.3 1 0 0 1 1 1 1 PUA domain RIC1 PF07064.8 EEQ33396.1 - 9.1e-80 267.8 0.0 1.3e-79 267.3 0.0 1.2 1 0 0 1 1 1 1 RIC1 TPR_11 PF13414.1 EEQ33397.1 - 1.6e-19 69.3 7.3 2.5e-16 59.0 2.2 2.5 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EEQ33397.1 - 3.2e-13 48.4 7.5 0.00034 20.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ33397.1 - 8.2e-13 47.3 5.7 3.8e-05 23.1 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ33397.1 - 2.3e-10 40.8 16.3 9.5e-08 32.5 2.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ33397.1 - 1.5e-07 31.0 1.2 0.0063 16.6 0.3 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ33397.1 - 2.8e-06 27.1 1.9 2.5e-05 24.0 0.3 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ33397.1 - 1e-05 25.7 5.6 0.032 14.8 0.3 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ33397.1 - 1.2e-05 25.1 3.1 0.0011 18.8 0.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ33397.1 - 1.8e-05 24.1 0.2 1.8 8.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33397.1 - 0.00084 19.6 1.4 0.0034 17.6 0.4 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ33397.1 - 0.0014 18.2 3.0 0.97 9.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat XPC-binding PF09280.6 EEQ33397.1 - 0.0064 15.9 4.7 0.0064 15.9 3.3 1.8 2 0 0 2 2 2 1 XPC-binding domain BTAD PF03704.12 EEQ33397.1 - 0.1 12.9 0.5 2.2 8.5 0.2 2.5 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 EEQ33397.1 - 0.7 10.4 5.3 11 6.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim44 PF04280.10 EEQ33398.1 - 1.5e-34 119.1 0.5 3.8e-34 117.7 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain CutA1 PF03091.10 EEQ33398.1 - 0.029 14.0 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein Ribosomal_S11 PF00411.14 EEQ33399.1 - 2.6e-08 34.0 0.0 9.9e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S11 Ank_5 PF13857.1 EEQ33400.1 - 2.7e-17 62.3 0.3 1.3e-11 44.3 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) VPS9 PF02204.13 EEQ33400.1 - 5e-17 61.8 0.0 1.4e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EEQ33400.1 - 5.2e-11 42.7 0.0 4.8e-07 30.0 0.0 3.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEQ33400.1 - 3.8e-08 32.8 0.2 0.74 10.2 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EEQ33400.1 - 4.3e-08 33.4 0.1 0.0098 16.3 0.0 4.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EEQ33400.1 - 9.5e-07 28.3 0.5 0.043 13.6 0.0 5.1 6 0 0 6 6 6 2 Ankyrin repeat PX PF00787.19 EEQ33400.1 - 6.9e-06 25.8 0.1 1.7e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 PX domain Ca_chan_IQ PF08763.6 EEQ33401.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Inhibitor_I78 PF11720.3 EEQ33402.1 - 2.1e-13 49.7 0.0 1.1e-10 41.1 0.0 2.1 1 1 1 2 2 2 2 Peptidase inhibitor I78 family Nefa_Nip30_N PF10187.4 EEQ33403.1 - 1.4e-27 95.8 9.5 3.4e-27 94.6 6.6 1.7 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 EEQ33403.1 - 0.021 13.8 1.5 0.025 13.5 1.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2570 PF10828.3 EEQ33403.1 - 0.072 12.6 3.5 0.086 12.4 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) CK_II_beta PF01214.13 EEQ33405.1 - 9.1e-73 243.6 0.1 9.1e-73 243.6 0.0 1.5 2 0 0 2 2 2 1 Casein kinase II regulatory subunit Myc_N PF01056.13 EEQ33405.1 - 0.079 12.1 2.1 0.13 11.3 1.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EEQ33405.1 - 0.11 12.0 8.2 0.2 11.1 5.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin PI3K_1B_p101 PF10486.4 EEQ33405.1 - 0.43 8.1 4.1 0.57 7.6 2.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3306 PF11748.3 EEQ33405.1 - 0.66 10.6 4.7 0.12 13.0 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) CENP-B_dimeris PF09026.5 EEQ33405.1 - 2.6 8.3 13.1 6.1 7.1 9.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain E1-E2_ATPase PF00122.15 EEQ33406.1 - 2.5e-47 160.8 3.4 2.5e-47 160.8 2.3 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ33406.1 - 1.2e-27 97.7 0.5 2.3e-27 96.8 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ33406.1 - 1.8e-11 44.5 0.0 1.9e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EEQ33406.1 - 4.2e-09 36.4 0.0 1.3e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EEQ33406.1 - 2.4e-05 24.0 0.2 0.028 14.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.3 EEQ33407.1 - 1.5e-32 112.6 0.2 5.7e-30 104.1 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ33407.1 - 9.7e-07 28.5 12.8 1.9e-06 27.6 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PucR PF07905.6 EEQ33407.1 - 0.13 11.8 0.0 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family Abhydrolase_3 PF07859.8 EEQ33408.1 - 3.7e-09 36.4 0.1 3.4e-08 33.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ33408.1 - 4.9e-05 23.1 0.1 8.1e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ33408.1 - 0.00064 19.6 1.9 0.001 18.9 1.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EEQ33408.1 - 0.0029 16.8 0.1 0.0089 15.2 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3089) DUF915 PF06028.6 EEQ33408.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 EEQ33408.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 EEQ33408.1 - 0.043 13.4 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EEQ33408.1 - 0.054 13.7 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EEQ33408.1 - 0.056 13.0 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.8 EEQ33408.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.15 EEQ33408.1 - 0.14 11.6 0.3 0.17 11.3 0.2 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold EB PF01683.13 EEQ33409.1 - 0.018 15.1 10.1 0.018 15.1 7.0 5.2 3 2 3 6 6 6 0 EB module JAB PF01398.16 EEQ33410.1 - 7.8e-07 28.8 0.1 3.4e-05 23.5 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Trypan_PARP PF05887.6 EEQ33412.1 - 0.00029 20.6 30.4 0.00029 20.6 21.1 14.3 6 3 9 16 16 16 1 Procyclic acidic repetitive protein (PARP) HMG_box PF00505.14 EEQ33413.1 - 1e-06 28.9 3.1 1e-06 28.9 2.1 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEQ33413.1 - 0.00011 22.4 5.5 0.00011 22.4 3.8 2.7 2 0 0 2 2 2 1 HMG-box domain XFP_N PF09364.5 EEQ33413.1 - 0.041 12.4 0.2 0.056 11.9 0.1 1.2 1 0 0 1 1 1 0 XFP N-terminal domain DUF1985 PF09331.6 EEQ33413.1 - 0.27 11.0 2.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) vMSA PF00695.14 EEQ33413.1 - 0.39 9.8 7.1 0.031 13.4 1.9 1.5 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus DEAD PF00270.24 EEQ33414.1 - 6.3e-45 152.6 0.0 1.2e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ33414.1 - 4.2e-24 84.2 0.0 1.2e-23 82.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ33414.1 - 0.00033 19.5 0.0 0.00058 18.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EEQ33414.1 - 0.025 14.3 1.7 0.14 11.9 0.0 3.1 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit zf-C2H2 PF00096.21 EEQ33416.1 - 2.2e-16 59.1 44.3 1.2e-06 28.4 0.3 7.6 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ33416.1 - 7.5e-15 54.3 46.2 9.2e-08 32.0 0.6 6.2 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ33416.1 - 1.8e-14 52.8 32.3 0.00017 21.7 0.6 7.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ33416.1 - 4.4e-12 45.7 1.1 0.0025 17.8 0.3 4.7 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ33416.1 - 6.9e-10 38.7 9.7 0.00025 21.1 0.2 5.2 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEQ33416.1 - 3.1e-06 26.8 13.7 0.017 14.9 0.8 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EEQ33416.1 - 0.0054 16.3 9.9 0.016 14.9 0.2 4.4 4 0 0 4 4 4 1 zinc-finger of a C2HC-type BolA PF01722.13 EEQ33416.1 - 0.016 15.1 0.1 0.97 9.4 0.0 2.4 1 1 1 2 2 2 0 BolA-like protein EB_dh PF09459.5 EEQ33416.1 - 0.065 12.6 0.7 2.8 7.3 0.3 2.1 2 0 0 2 2 2 0 Ethylbenzene dehydrogenase DUF533 PF04391.7 EEQ33418.1 - 0.012 14.9 0.5 0.022 14.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) zf-C2H2_4 PF13894.1 EEQ33419.1 - 1.3e-06 28.3 14.8 2.2e-05 24.4 1.6 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ33419.1 - 3.9e-06 26.8 13.3 2.6e-05 24.2 2.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ33419.1 - 7.5e-06 25.9 3.1 7.5e-06 25.9 2.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EEQ33419.1 - 0.00027 21.0 7.2 0.0016 18.5 0.7 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF2225 PF09986.4 EEQ33419.1 - 0.0041 16.6 0.1 0.0063 16.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 EEQ33419.1 - 0.027 14.6 1.3 0.027 14.6 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ33419.1 - 0.18 11.7 1.3 0.51 10.3 0.9 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger GnHR_trans PF12369.3 EEQ33419.1 - 0.7 10.3 3.2 1.1 9.7 0.1 2.8 2 1 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region zf-Di19 PF05605.7 EEQ33419.1 - 1 9.5 6.4 2.5 8.2 4.4 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Prok-JAB PF14464.1 EEQ33420.1 - 0.053 13.0 0.3 0.066 12.7 0.2 1.2 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Mid2 PF04478.7 EEQ33422.1 - 0.034 13.5 0.2 0.07 12.5 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.5 EEQ33422.1 - 0.074 12.3 1.2 0.14 11.5 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HAT PF02184.11 EEQ33423.1 - 1.5e-26 91.8 74.8 1.6e-16 59.7 1.8 13.3 14 0 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EEQ33423.1 - 6e-20 69.9 13.9 0.026 15.1 0.0 11.1 5 2 7 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33423.1 - 2.4e-16 59.8 0.0 0.006 16.8 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ33423.1 - 2.2e-14 53.6 6.9 0.41 11.3 0.6 8.1 8 1 2 10 10 10 3 Tetratricopeptide repeat Suf PF05843.9 EEQ33423.1 - 1.2e-11 44.8 28.5 0.00025 20.8 1.5 6.4 2 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EEQ33423.1 - 2.4e-09 36.7 0.5 0.14 11.8 0.0 5.6 5 0 0 5 5 5 3 TPR repeat TPR_17 PF13431.1 EEQ33423.1 - 3.7e-06 26.6 0.1 1.7 9.0 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ33423.1 - 8.4e-06 25.3 8.8 2.4 8.2 0.0 7.6 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ33423.1 - 0.00026 21.2 19.0 0.6 10.6 0.0 8.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ33423.1 - 0.00053 19.8 16.1 7.9 6.5 0.0 8.3 8 2 4 12 12 11 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EEQ33423.1 - 0.00088 18.9 28.7 0.018 14.7 1.9 6.8 5 3 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 EEQ33423.1 - 0.0066 15.3 2.2 0.0066 15.3 1.5 6.3 3 3 3 6 6 6 1 NRDE-2, necessary for RNA interference TPR_1 PF00515.23 EEQ33423.1 - 0.0071 15.9 1.1 39 4.0 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ33423.1 - 0.009 15.7 12.3 10 6.2 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEQ33423.1 - 1.1 9.2 8.9 3.9 7.4 0.3 4.9 7 0 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat Prp31_C PF09785.4 EEQ33424.1 - 2.7e-45 153.7 0.7 4.9e-45 152.9 0.5 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EEQ33424.1 - 2.6e-40 137.1 0.0 5e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEQ33424.1 - 7.4e-22 76.9 0.1 1.3e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain AdoHcyase PF05221.12 EEQ33425.1 - 3.4e-137 455.7 0.1 3.9e-137 455.5 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EEQ33425.1 - 7.6e-85 282.7 2.3 1.5e-84 281.7 1.6 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEQ33425.1 - 1.8e-07 30.4 0.1 3.7e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EEQ33425.1 - 0.00011 21.5 0.2 0.0002 20.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EEQ33425.1 - 0.00097 19.1 0.1 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EEQ33425.1 - 0.013 15.0 0.8 0.026 14.0 0.5 1.6 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 EEQ33425.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3759 PF12585.3 EEQ33427.1 - 2.1e-39 133.3 7.2 2.4e-39 133.1 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Phe_ZIP PF08916.6 EEQ33427.1 - 0.063 13.5 0.3 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Phenylalanine zipper Peptidase_C13 PF01650.13 EEQ33428.1 - 0.0091 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Band_7 PF01145.20 EEQ33429.1 - 2.9e-30 105.4 0.7 2.9e-30 105.4 0.5 1.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family RecX PF02631.11 EEQ33429.1 - 0.011 15.9 1.8 0.023 14.8 0.4 2.1 1 1 1 2 2 2 0 RecX family Band_7_1 PF13421.1 EEQ33429.1 - 0.022 14.2 0.0 0.054 13.0 0.0 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family Mod_r PF07200.8 EEQ33431.1 - 2.2e-13 50.3 2.1 3e-13 49.9 1.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PAP2 PF01569.16 EEQ33432.1 - 5.9e-18 64.7 0.9 1.6e-17 63.3 0.6 1.7 1 0 0 1 1 1 1 PAP2 superfamily Aldo_ket_red PF00248.16 EEQ33433.1 - 1.1e-52 178.6 0.0 1.2e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Reo_sigmaC PF04582.7 EEQ33434.1 - 0.0036 16.5 0.4 0.0042 16.2 0.3 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein GFA PF04828.9 EEQ33435.1 - 2.2e-12 46.7 0.1 3.3e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.8 EEQ33436.1 - 2.4e-05 24.1 0.4 3.7e-05 23.5 0.3 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EEQ33436.1 - 0.02 14.9 1.1 0.044 13.8 0.4 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EEQ33436.1 - 0.069 13.1 1.8 1.3 9.0 0.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NPR3 PF03666.8 EEQ33437.1 - 2.5e-144 481.2 0.4 2.3e-143 478.0 0.0 2.2 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EEQ33437.1 - 0.00091 18.0 0.0 0.0021 16.8 0.0 1.5 1 0 0 1 1 1 1 Nitrogen permease regulator 2 La PF05383.12 EEQ33438.1 - 3.4e-18 65.1 0.4 6.8e-18 64.2 0.3 1.5 1 0 0 1 1 1 1 La domain Ank_5 PF13857.1 EEQ33440.1 - 1e-10 41.5 0.0 5.7e-09 35.9 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ33440.1 - 4.7e-10 39.7 0.0 6.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ33440.1 - 1.4e-06 28.5 0.1 2.2e-05 24.7 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ33440.1 - 5.5e-06 25.9 0.1 0.0006 19.4 0.1 2.9 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EEQ33440.1 - 1.6e-05 24.6 0.0 0.004 17.2 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat YejG PF13989.1 EEQ33440.1 - 0.066 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 YejG-like protein F-box PF00646.28 EEQ33441.1 - 0.0034 17.0 0.0 0.0034 17.0 0.0 3.5 5 0 0 5 5 5 1 F-box domain F-box-like PF12937.2 EEQ33441.1 - 0.092 12.4 0.2 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 F-box-like RNA_lig_T4_1 PF09511.5 EEQ33442.1 - 1.2e-81 273.4 0.1 4.6e-81 271.5 0.0 2.0 2 0 0 2 2 2 1 RNA ligase tRNA_lig_CPD PF08302.6 EEQ33442.1 - 8.3e-78 261.1 0.0 1.3e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EEQ33442.1 - 2.2e-45 154.5 0.9 7.9e-45 152.7 0.3 2.2 2 1 0 2 2 2 1 tRNA ligase kinase domain AAA_17 PF13207.1 EEQ33442.1 - 0.015 16.0 0.0 0.053 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4150 PF13665.1 EEQ33442.1 - 0.026 14.4 0.5 0.051 13.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) HLH PF00010.21 EEQ33443.1 - 5.7e-11 41.9 0.1 1.3e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_carr PF00153.22 EEQ33444.1 - 4e-46 154.6 3.8 1.4e-20 72.7 0.0 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein Dna2 PF08696.6 EEQ33445.1 - 4e-71 238.6 0.1 6.8e-71 237.8 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EEQ33445.1 - 8e-54 182.0 0.0 1.3e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ33445.1 - 4.7e-42 144.1 0.1 2.8e-39 135.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EEQ33445.1 - 9.5e-13 48.1 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ33445.1 - 1.4e-10 40.7 0.1 3.9e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 EEQ33445.1 - 6.6e-10 38.7 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 EEQ33445.1 - 4.8e-07 29.5 0.4 0.18 11.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.12 EEQ33445.1 - 5.4e-07 29.6 0.0 0.56 10.0 0.0 3.4 2 1 1 3 3 3 2 Domain of unknown function DUF83 Helicase_RecD PF05127.9 EEQ33445.1 - 0.0001 21.9 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EEQ33445.1 - 0.00029 20.2 0.8 0.00076 18.8 0.1 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 EEQ33445.1 - 0.00079 18.9 0.1 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 EEQ33445.1 - 0.0019 17.8 0.0 0.0045 16.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EEQ33445.1 - 0.0025 17.2 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.9 EEQ33445.1 - 0.0025 16.8 0.0 0.0055 15.6 0.0 1.6 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 EEQ33445.1 - 0.0038 17.2 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EEQ33445.1 - 0.004 16.5 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EEQ33445.1 - 0.0071 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 EEQ33445.1 - 0.01 16.2 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EEQ33445.1 - 0.011 15.1 0.1 0.13 11.6 0.0 2.4 3 0 0 3 3 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 EEQ33445.1 - 0.048 13.4 0.2 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA PF00004.24 EEQ33445.1 - 0.06 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ33445.1 - 0.06 13.4 0.0 0.24 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEQ33445.1 - 0.063 13.1 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 EEQ33445.1 - 0.086 12.5 0.2 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase ArgK PF03308.11 EEQ33445.1 - 0.13 11.0 0.1 0.29 9.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein Arch_ATPase PF01637.13 EEQ33445.1 - 0.19 11.4 0.0 0.51 9.9 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 EEQ33445.1 - 0.25 10.1 0.8 1.4 7.6 0.1 2.3 3 0 0 3 3 3 0 NB-ARC domain Ribonuc_P_40 PF08584.6 EEQ33446.1 - 1.9e-83 279.7 0.0 2.3e-83 279.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 EEQ33447.1 - 8e-37 123.8 13.1 7.3e-09 35.1 0.0 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EEQ33447.1 - 2.3e-06 26.1 0.0 0.0042 15.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EEQ33447.1 - 0.00016 21.4 0.1 0.91 9.2 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEQ33447.1 - 0.045 11.8 0.1 2.1 6.4 0.0 2.1 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Fungal_trans PF04082.13 EEQ33448.1 - 1.5e-17 63.3 0.4 2.7e-17 62.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ33448.1 - 2.7e-10 39.9 9.3 5.7e-10 38.9 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.13 EEQ33449.1 - 1.2e-44 151.2 2.4 1.9e-33 115.0 0.9 2.4 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEQ33449.1 - 1.1e-26 92.5 0.4 2e-26 91.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 EEQ33450.1 - 4.1e-46 155.6 0.1 4.1e-44 149.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEQ33450.1 - 3.4e-31 107.6 0.0 6.6e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.18 EEQ33451.1 - 6.8e-17 61.8 0.1 2.1e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EEQ33451.1 - 1.5e-06 28.4 0.0 3e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EEQ33451.1 - 0.023 14.3 0.2 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.13 EEQ33452.1 - 1.4e-12 47.5 0.0 2.7e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EEQ33452.1 - 8.9e-10 38.6 0.0 2.2e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.11 EEQ33452.1 - 6.8e-06 25.3 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 EEQ33452.1 - 0.12 11.8 0.1 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.10 EEQ33452.1 - 0.16 11.3 0.0 0.82 9.0 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical protein 95 DUF2985 PF11204.3 EEQ33454.1 - 2.6e-29 100.7 5.8 6.2e-29 99.5 4.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) SIR2 PF02146.12 EEQ33455.1 - 3e-59 199.7 0.0 4.4e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EEQ33455.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EEQ33455.1 - 0.00017 21.3 0.4 0.93 9.2 0.0 2.9 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain TPR_11 PF13414.1 EEQ33456.1 - 1.5e-13 50.1 0.0 4.1e-08 32.7 0.0 3.7 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EEQ33456.1 - 6.8e-13 47.4 0.0 5.4e-05 22.7 0.0 5.5 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ33456.1 - 6.8e-13 48.3 0.0 1e-08 34.9 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33456.1 - 1.2e-11 44.7 1.9 1.3e-05 25.4 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ33456.1 - 4e-10 40.0 0.0 2.8e-05 24.6 0.0 4.6 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ33456.1 - 5.1e-09 35.9 2.3 0.15 12.7 0.0 5.4 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ33456.1 - 8.2e-09 34.7 0.0 0.0018 17.8 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ33456.1 - 4.2e-08 32.9 0.5 3.3 7.6 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ33456.1 - 8.6e-07 28.3 0.0 0.0026 17.4 0.0 3.6 5 0 0 5 5 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ33456.1 - 2.8e-06 26.7 0.0 0.0061 16.2 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ33456.1 - 3.2e-06 26.9 0.0 14 6.1 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EEQ33456.1 - 3.4e-06 27.1 0.0 0.0029 17.7 0.0 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EEQ33456.1 - 4.9e-05 23.1 0.2 0.035 14.0 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 EEQ33456.1 - 0.00032 20.6 0.0 0.02 14.8 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ33456.1 - 0.0011 19.3 0.5 10 6.8 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ33456.1 - 0.0011 18.0 0.1 0.067 12.2 0.0 3.1 2 2 1 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EEQ33456.1 - 0.002 17.4 0.0 0.12 11.4 0.0 2.4 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_4 PF07721.9 EEQ33456.1 - 0.0025 18.0 3.9 0.031 14.6 0.0 3.4 4 0 0 4 4 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EEQ33456.1 - 0.0036 16.5 0.5 0.12 11.5 0.0 2.6 2 0 0 2 2 2 1 SHNi-TPR Peptidase_C50 PF03568.12 EEQ33456.1 - 0.025 13.2 0.1 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C50 TPR_5 PF12688.2 EEQ33456.1 - 0.028 14.4 0.0 0.089 12.8 0.0 1.9 1 0 0 1 1 1 0 Tetratrico peptide repeat RWD PF05773.17 EEQ33457.1 - 1.2e-23 83.1 0.4 1.2e-23 83.1 0.3 1.6 2 0 0 2 2 2 1 RWD domain DUF1485 PF07364.7 EEQ33457.1 - 0.002 17.3 0.0 0.02 14.1 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1485) RNase_H2-Ydr279 PF09468.5 EEQ33457.1 - 0.0079 15.4 1.8 0.0087 15.2 1.2 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 EEQ33457.1 - 0.85 9.4 4.4 1.3 8.7 3.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal APG6 PF04111.7 EEQ33457.1 - 2.5 7.0 9.4 3.8 6.4 6.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Pyridox_oxidase PF01243.15 EEQ33458.1 - 0.00038 20.4 0.0 0.00098 19.0 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GST_C PF00043.20 EEQ33459.1 - 8.5e-18 64.1 0.3 2e-17 62.9 0.1 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEQ33459.1 - 1.7e-13 50.5 0.0 3.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ33459.1 - 4.8e-12 45.7 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEQ33459.1 - 2.4e-11 43.6 0.0 4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ33459.1 - 3.8e-10 39.5 0.2 2.4e-09 36.9 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ33459.1 - 0.00024 21.5 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Complex1_LYR_1 PF13232.1 EEQ33460.1 - 1.5e-14 53.9 0.0 3.9e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEQ33460.1 - 2.9e-10 39.7 0.0 6e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Use1 PF09753.4 EEQ33460.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 UQ_con PF00179.21 EEQ33461.1 - 2.9e-10 39.7 0.0 3.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEQ33461.1 - 0.011 15.6 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.2 EEQ33462.1 - 2.5e-35 121.3 3.4 2.5e-35 121.3 2.4 4.2 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EEQ33462.1 - 0.00098 18.5 6.3 0.015 14.8 0.0 5.2 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Antimicrobial19 PF08225.6 EEQ33462.1 - 0.15 11.4 0.0 0.46 9.9 0.0 1.8 1 0 0 1 1 1 0 Pseudin antimicrobial peptide Vps26 PF03643.10 EEQ33463.1 - 4.9e-129 428.9 0.1 5.8e-129 428.7 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EEQ33463.1 - 0.0023 17.7 0.2 3.3 7.5 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 EEQ33463.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) AAA_33 PF13671.1 EEQ33466.1 - 5e-13 49.1 0.0 1.5e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ33466.1 - 1.1e-11 45.0 0.0 2.1e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EEQ33466.1 - 3.9e-11 43.0 0.0 1.3e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EEQ33466.1 - 1.3e-10 42.1 0.0 1.8e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EEQ33466.1 - 9.6e-07 27.8 0.0 1.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EEQ33466.1 - 7e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEQ33466.1 - 0.00012 21.9 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EEQ33466.1 - 0.00014 21.8 0.0 0.007 16.2 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_22 PF13401.1 EEQ33466.1 - 0.00022 21.3 0.0 0.00055 20.0 0.0 1.7 1 1 0 2 2 1 1 AAA domain NACHT PF05729.7 EEQ33466.1 - 0.00047 19.8 0.0 0.0009 18.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EEQ33466.1 - 0.00066 19.3 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EEQ33466.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEQ33466.1 - 0.0016 18.6 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Herpes_Helicase PF02689.9 EEQ33466.1 - 0.0025 15.6 0.0 0.0033 15.2 0.0 1.1 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.1 EEQ33466.1 - 0.0034 17.3 0.0 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.15 EEQ33466.1 - 0.006 16.2 0.0 0.024 14.3 0.0 1.9 1 1 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 EEQ33466.1 - 0.013 14.6 0.1 0.027 13.5 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin tRNA_lig_kinase PF08303.6 EEQ33466.1 - 0.014 15.3 0.0 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 tRNA ligase kinase domain PRK PF00485.13 EEQ33466.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.4 EEQ33466.1 - 0.02 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EEQ33466.1 - 0.023 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase RuvB_N PF05496.7 EEQ33466.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EEQ33466.1 - 0.033 13.6 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EEQ33466.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 NTPase CoaE PF01121.15 EEQ33466.1 - 0.037 13.4 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_25 PF13481.1 EEQ33466.1 - 0.039 13.3 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEQ33466.1 - 0.041 14.1 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EEQ33466.1 - 0.049 13.3 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EEQ33466.1 - 0.05 12.7 0.0 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEQ33466.1 - 0.063 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EEQ33466.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EEQ33466.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ADK PF00406.17 EEQ33466.1 - 0.081 12.7 0.1 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase PduV-EutP PF10662.4 EEQ33466.1 - 0.087 12.3 0.0 0.51 9.8 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KTI12 PF08433.5 EEQ33466.1 - 0.098 11.8 0.1 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PhoH PF02562.11 EEQ33466.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 EEQ33466.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Acetyltransf_3 PF13302.1 EEQ33467.1 - 6.2e-19 68.5 0.0 8.2e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C14 PF00656.17 EEQ33468.1 - 2.9e-44 151.6 0.0 2.2e-24 86.4 0.0 2.1 1 1 1 2 2 2 2 Caspase domain 2-oxoacid_dh PF00198.18 EEQ33469.1 - 1.6e-78 263.1 0.4 2.2e-78 262.7 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 EEQ33469.1 - 1.7e-14 53.1 0.0 3.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 EEQ33469.1 - 1.4e-12 47.0 0.0 5.4e-12 45.1 0.0 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme PI-PLC-X PF00388.14 EEQ33470.1 - 4.7e-13 48.7 0.0 8.6e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain HrpB2 PF09487.5 EEQ33470.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Auxin_repressed PF05564.7 EEQ33471.1 - 0.085 13.4 0.3 0.16 12.5 0.2 1.5 1 0 0 1 1 1 0 Dormancy/auxin associated protein Ribosomal_L10 PF00466.15 EEQ33471.1 - 0.12 12.3 0.1 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L10 F-box PF00646.28 EEQ33472.1 - 0.3 10.7 3.1 0.13 11.9 0.2 1.9 2 0 0 2 2 2 0 F-box domain Glycos_transf_3 PF00591.16 EEQ33473.1 - 7.3e-57 192.6 0.0 5.5e-54 183.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EEQ33473.1 - 2.2e-05 23.9 0.2 4.6e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.8 EEQ33474.1 - 3.7e-17 61.4 7.1 4.8e-17 61.1 4.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2318 PF10080.4 EEQ33474.1 - 0.00095 18.8 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) HypA PF01155.14 EEQ33474.1 - 0.0013 18.4 0.4 0.0014 18.2 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DUF2197 PF09963.4 EEQ33474.1 - 0.0034 17.3 2.8 0.24 11.3 0.1 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.2 EEQ33474.1 - 0.0046 16.7 0.2 0.0064 16.2 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 EEQ33474.1 - 0.0068 15.8 2.4 0.084 12.3 0.2 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EEQ33474.1 - 0.0092 15.9 1.5 0.016 15.1 1.0 1.4 1 0 0 1 1 1 1 Zinc ribbon domain GFA PF04828.9 EEQ33474.1 - 0.0096 15.8 0.7 2.4 8.1 0.1 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF2082 PF09855.4 EEQ33474.1 - 0.11 12.3 1.6 0.2 11.5 1.1 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) UPF0547 PF10571.4 EEQ33474.1 - 0.2 11.3 1.8 0.42 10.3 1.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS1595 PF12760.2 EEQ33474.1 - 0.27 11.0 3.2 0.7 9.7 2.2 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain RRN7 PF11781.3 EEQ33474.1 - 0.28 10.7 3.4 0.99 8.9 0.1 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF951 PF06107.6 EEQ33474.1 - 0.29 10.6 3.2 1.4 8.5 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) TFIIS_C PF01096.13 EEQ33474.1 - 0.57 9.8 4.9 4.9 6.8 0.6 2.4 1 1 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.1 EEQ33474.1 - 0.93 9.8 6.0 2.4 8.4 0.7 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF3133 PF11331.3 EEQ33474.1 - 7 6.3 6.4 1.8e+02 1.7 4.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) fn3 PF00041.16 EEQ33475.1 - 3.4e-13 49.5 5.0 4.1e-08 33.2 0.0 3.8 3 1 0 3 3 3 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 EEQ33475.1 - 1.2e-08 35.3 0.1 4.3e-08 33.4 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ33475.1 - 1.5e-07 31.5 0.0 5.5e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fe_hyd_lg_C PF02906.9 EEQ33477.1 - 4.2e-60 203.4 0.0 7.1e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain HTH_18 PF12833.2 EEQ33477.1 - 0.1 12.7 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain UbiA PF01040.13 EEQ33478.1 - 2.5e-16 59.6 15.5 3.5e-16 59.1 10.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4401 PF14351.1 EEQ33478.1 - 0.052 12.5 9.7 1.6 7.6 6.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) DUF2427 PF10348.4 EEQ33478.1 - 6.7 6.3 6.6 14 5.3 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) DUF2263 PF10021.4 EEQ33479.1 - 2.5e-28 98.9 0.0 6.6e-28 97.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Fapy_DNA_glyco PF01149.19 EEQ33480.1 - 1.4e-25 89.8 0.0 2.8e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EEQ33480.1 - 5.8e-21 74.0 0.0 1e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EEQ33480.1 - 0.0039 15.7 0.0 0.016 13.8 0.0 1.8 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1510 PF07423.6 EEQ33480.1 - 0.024 14.0 4.2 0.052 12.9 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cid2 PF09774.4 EEQ33481.1 - 1.2e-51 174.7 0.0 1.4e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.3 EEQ33482.1 - 3.1e-211 702.6 8.2 1.2e-210 700.7 1.3 2.3 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 EEQ33482.1 - 7.4e-25 85.1 14.7 0.00065 20.1 0.5 10.8 7 3 4 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ33482.1 - 4.2e-21 74.3 32.6 0.00017 21.1 0.4 7.9 7 1 1 8 8 7 5 TPR repeat TPR_16 PF13432.1 EEQ33482.1 - 2.7e-20 72.4 19.5 0.0034 18.0 0.8 8.7 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ33482.1 - 1.6e-19 68.1 37.0 8.1e-05 22.2 0.4 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33482.1 - 2.6e-17 62.8 32.6 0.00091 19.5 0.0 7.3 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ33482.1 - 8.1e-12 44.2 36.4 1.2e-05 24.7 0.4 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ33482.1 - 4.4e-11 42.4 16.1 0.0071 16.1 1.4 7.3 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ33482.1 - 8.1e-10 38.1 19.0 0.16 12.2 0.0 8.2 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ33482.1 - 7.7e-09 34.7 17.7 0.0014 18.2 0.1 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ33482.1 - 9.5e-08 31.8 31.4 0.0011 18.8 0.2 7.5 6 2 2 8 8 7 4 Tetratricopeptide repeat Apc3 PF12895.2 EEQ33482.1 - 1e-05 25.5 17.0 0.076 13.1 2.3 5.6 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EEQ33482.1 - 1.3e-05 24.6 10.1 0.48 10.3 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_3 PF07720.7 EEQ33482.1 - 1.9e-05 24.3 0.5 0.013 15.2 0.1 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ33482.1 - 6.4e-05 23.1 22.9 0.046 14.1 0.1 8.0 9 0 0 9 9 7 2 Tetratricopeptide repeat BTAD PF03704.12 EEQ33482.1 - 8.8e-05 22.8 2.5 0.0029 17.9 0.1 3.2 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 EEQ33482.1 - 0.00021 20.4 13.6 0.051 12.6 2.2 3.9 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEQ33482.1 - 0.0027 17.5 11.7 9.9 6.1 0.0 5.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 EEQ33482.1 - 0.0032 17.7 7.0 5.6 7.7 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 EEQ33482.1 - 0.0084 15.8 0.0 0.054 13.3 0.0 2.5 1 0 0 1 1 1 1 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.1 EEQ33482.1 - 0.29 11.1 16.0 7.3 6.6 0.9 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Tim54 PF11711.3 EEQ33483.1 - 3.2e-130 434.1 0.1 3.8e-130 433.8 0.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 EEQ33484.1 - 9.1e-54 182.3 0.1 1.6e-37 129.0 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33484.1 - 2.6e-24 85.6 0.4 7.5e-19 67.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ33484.1 - 0.0001 21.3 0.0 0.0002 20.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ33484.1 - 0.0015 17.5 0.0 0.0033 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ33484.1 - 0.0028 17.4 3.2 0.017 14.8 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 EEQ33484.1 - 0.013 15.9 0.0 0.038 14.5 0.0 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain PepX_N PF09168.5 EEQ33484.1 - 0.025 14.8 0.5 0.055 13.7 0.4 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Seadorna_VP7 PF07387.6 EEQ33484.1 - 0.039 12.8 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EEQ33484.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3441 PF11923.3 EEQ33484.1 - 0.14 11.7 0.2 0.27 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) RIO1 PF01163.17 EEQ33484.1 - 0.18 11.1 2.6 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family SpoIIIAH PF12685.2 EEQ33484.1 - 0.21 11.0 2.3 0.38 10.2 1.6 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIA PF03153.8 EEQ33484.1 - 7.2 6.4 18.9 11 5.8 13.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-met PF12874.2 EEQ33485.1 - 2.1e-05 24.5 0.6 3.8e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EEQ33485.1 - 0.047 12.9 0.9 0.095 11.9 0.6 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like p450 PF00067.17 EEQ33486.1 - 5.1e-63 213.1 0.0 6.7e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RRN9 PF10680.4 EEQ33486.1 - 0.035 13.8 0.0 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor TPR_12 PF13424.1 EEQ33487.1 - 6.4e-37 125.3 18.1 1.9e-12 46.9 0.4 5.7 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ33487.1 - 3.2e-29 99.9 8.8 0.00015 21.5 0.0 8.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ33487.1 - 2.1e-08 34.6 12.3 0.049 14.3 0.5 6.4 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ33487.1 - 2.3e-08 33.5 5.4 0.04 13.5 0.1 5.0 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 EEQ33487.1 - 5.8e-06 25.6 0.8 0.29 10.8 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33487.1 - 6.3e-06 26.4 8.6 0.26 11.6 0.2 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ33487.1 - 2.9e-05 24.1 0.1 1.1 9.3 0.0 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EEQ33487.1 - 3.5e-05 23.3 13.1 2.4 8.3 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ33487.1 - 5.9e-05 22.5 7.5 7.2 6.6 0.0 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.17 EEQ33487.1 - 0.00018 20.5 0.0 0.00046 19.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EEQ33487.1 - 0.00034 20.7 0.0 0.002 18.2 0.0 2.4 1 0 0 1 1 1 1 AAA domain TPR_4 PF07721.9 EEQ33487.1 - 0.0023 18.2 19.9 0.15 12.5 0.4 5.9 6 0 0 6 6 4 2 Tetratricopeptide repeat AAA_24 PF13479.1 EEQ33487.1 - 0.023 14.2 0.1 0.48 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain TPR_8 PF13181.1 EEQ33487.1 - 0.045 13.5 2.2 28 4.8 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4477 PF14780.1 EEQ33487.1 - 0.05 12.9 0.2 0.16 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) TPR_17 PF13431.1 EEQ33487.1 - 0.05 13.8 8.2 5.8 7.3 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ33487.1 - 0.12 13.0 18.6 2.5 8.9 0.2 7.3 5 2 3 8 8 8 0 Tetratricopeptide repeat DUF1664 PF07889.7 EEQ33487.1 - 0.15 11.8 10.5 0.66 9.7 0.2 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) TPR_5 PF12688.2 EEQ33487.1 - 0.22 11.5 2.1 3.9 7.5 0.1 3.5 4 0 0 4 4 4 0 Tetratrico peptide repeat TPR_6 PF13174.1 EEQ33487.1 - 0.98 10.0 11.7 23 5.7 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Ank_2 PF12796.2 EEQ33488.1 - 1.7e-108 355.1 15.9 1.4e-18 66.9 0.2 10.7 2 2 9 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ33488.1 - 6e-82 265.6 23.6 1.6e-07 30.7 0.0 20.0 20 0 0 20 20 20 15 Ankyrin repeat Ank_4 PF13637.1 EEQ33488.1 - 2.2e-74 244.6 24.1 9.1e-09 35.6 0.1 16.4 9 5 6 17 17 17 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ33488.1 - 1.3e-62 201.4 20.9 0.00039 20.3 0.0 20.4 20 1 0 20 20 20 15 Ankyrin repeat Ank_5 PF13857.1 EEQ33488.1 - 1.4e-62 206.2 17.1 5.1e-07 29.7 0.0 15.8 11 3 4 16 16 16 13 Ankyrin repeats (many copies) F-box-like PF12937.2 EEQ33488.1 - 0.036 13.7 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 F-box-like Stc1 PF12898.2 EEQ33489.1 - 0.00059 19.8 0.1 0.00098 19.1 0.1 1.3 1 0 0 1 1 1 1 Stc1 domain A2L_zn_ribbon PF08792.5 EEQ33489.1 - 0.01 15.2 1.1 0.41 10.1 0.2 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-dskA_traR PF01258.12 EEQ33489.1 - 0.63 9.8 4.2 16 5.3 0.7 3.1 2 1 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger GFA PF04828.9 EEQ33489.1 - 0.97 9.4 3.9 7.6 6.5 2.4 2.3 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme LRR_4 PF12799.2 EEQ33490.1 - 1.2e-12 47.1 7.0 0.00024 20.6 0.2 4.5 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EEQ33490.1 - 0.0003 20.5 8.8 1 9.6 0.4 4.7 4 1 1 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 EEQ33490.1 - 0.00036 20.1 10.2 0.77 10.0 0.1 5.0 4 1 1 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EEQ33490.1 - 0.0026 17.6 4.6 11 6.7 0.1 4.9 4 0 0 4 4 4 1 Leucine rich repeat LRR_8 PF13855.1 EEQ33490.1 - 0.62 9.8 17.2 0.32 10.7 1.1 4.5 3 1 2 6 6 6 0 Leucine rich repeat Zn_clus PF00172.13 EEQ33491.1 - 1.2e-08 34.7 10.4 2e-08 34.0 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 EEQ33492.1 - 2.5e-56 189.6 0.0 3.4e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ33492.1 - 1.6e-13 50.2 0.0 1.9e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEQ33492.1 - 4.1e-05 23.4 0.2 6.8e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EEQ33492.1 - 0.086 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain CwfJ_C_1 PF04677.10 EEQ33493.1 - 1.2e-30 105.6 0.0 3.2e-30 104.2 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EEQ33493.1 - 3.7e-23 81.8 0.0 1.5e-22 79.9 0.0 2.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.4 EEQ33493.1 - 0.083 12.9 0.7 13 5.9 0.0 2.8 2 0 0 2 2 2 0 Fumarase C C-terminus REF PF05755.7 EEQ33493.1 - 0.088 12.5 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) ATP_bind_1 PF03029.12 EEQ33494.1 - 2.7e-75 252.9 0.0 3.5e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EEQ33494.1 - 6.3e-05 22.4 0.0 0.0018 17.7 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EEQ33494.1 - 0.00012 20.9 0.0 0.015 14.1 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 EEQ33494.1 - 0.00022 21.3 0.0 0.00067 19.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EEQ33494.1 - 0.00029 20.7 0.0 0.00089 19.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EEQ33494.1 - 0.00076 19.0 0.2 0.0011 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain SRP54 PF00448.17 EEQ33494.1 - 0.0017 17.7 0.0 0.021 14.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Miro PF08477.8 EEQ33494.1 - 0.0018 18.7 0.0 2.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein FeoB_N PF02421.13 EEQ33494.1 - 0.0027 17.0 0.0 0.068 12.4 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B PRK PF00485.13 EEQ33494.1 - 0.0034 16.9 0.0 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EEQ33494.1 - 0.0035 17.0 0.0 0.0094 15.6 0.0 1.6 2 0 0 2 2 1 1 NACHT domain CbiA PF01656.18 EEQ33494.1 - 0.0079 15.6 0.0 0.029 13.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EEQ33494.1 - 0.0082 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEQ33494.1 - 0.0084 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arf PF00025.16 EEQ33494.1 - 0.01 15.1 0.0 1.9 7.6 0.0 3.0 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_17 PF13207.1 EEQ33494.1 - 0.015 16.1 0.1 0.12 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EEQ33494.1 - 0.017 14.5 0.0 1.5 8.2 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EEQ33494.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EEQ33494.1 - 0.03 13.1 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EEQ33494.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 EEQ33494.1 - 0.069 12.6 0.1 0.73 9.3 0.0 2.6 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 EEQ33494.1 - 0.14 10.8 2.9 1.7 7.2 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit DUF3537 PF12056.3 EEQ33495.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF872 PF05915.7 EEQ33495.1 - 0.15 11.9 0.4 0.99 9.2 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) GST_N_3 PF13417.1 EEQ33496.1 - 8.1e-23 80.4 0.0 1.6e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ33496.1 - 6.5e-13 48.4 0.0 1.6e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ33496.1 - 5.9e-06 26.0 0.1 1.3e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EEQ33496.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin SUZ PF12752.2 EEQ33497.1 - 0.0041 17.6 5.8 0.0041 17.6 4.0 4.1 4 1 0 4 4 4 1 SUZ domain EGL-1 PF11430.3 EEQ33498.1 - 0.52 9.9 4.7 1 9.0 3.3 1.5 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 AAA_12 PF13087.1 EEQ33500.1 - 3.1e-41 140.9 1.8 6.1e-41 140.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEQ33500.1 - 3.1e-41 140.6 0.0 2.3e-12 47.2 0.0 5.3 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EEQ33500.1 - 1.1e-24 87.3 0.0 1.1e-24 87.3 0.0 7.2 5 2 0 6 6 4 2 AAA domain AAA_19 PF13245.1 EEQ33500.1 - 1.4e-20 72.8 0.3 2.3e-07 30.4 0.0 4.9 4 0 0 4 4 4 4 Part of AAA domain AAA_22 PF13401.1 EEQ33500.1 - 2.6e-14 53.4 8.0 0.0046 17.0 0.0 8.0 5 3 0 5 5 5 3 AAA domain AAA_5 PF07728.9 EEQ33500.1 - 4.5e-14 52.3 0.3 0.0058 16.3 0.0 4.9 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EEQ33500.1 - 6.1e-13 48.8 9.3 0.0015 18.1 0.0 7.3 6 2 0 6 6 5 3 AAA domain AAA_17 PF13207.1 EEQ33500.1 - 1.8e-12 48.1 14.6 0.018 15.8 0.0 6.2 6 0 0 6 6 4 4 AAA domain Mg_chelatase PF01078.16 EEQ33500.1 - 1.6e-10 40.5 0.5 0.076 12.1 0.0 4.8 5 0 0 5 5 5 4 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EEQ33500.1 - 1.1e-09 38.0 0.1 0.036 13.4 0.0 5.0 4 0 0 4 4 4 3 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EEQ33500.1 - 1.9e-09 37.4 0.1 0.024 14.1 0.0 6.0 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EEQ33500.1 - 6.2e-08 32.7 0.2 2.6 8.2 0.0 5.0 4 0 0 4 4 4 1 RNA helicase AAA_18 PF13238.1 EEQ33500.1 - 2e-06 28.1 23.6 0.21 11.8 0.0 7.1 7 0 0 7 7 5 4 AAA domain AAA_24 PF13479.1 EEQ33500.1 - 3.1e-05 23.6 7.0 1.6 8.2 0.1 4.6 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 EEQ33500.1 - 7.7e-05 22.7 20.6 0.44 10.4 0.0 5.8 6 0 0 6 6 4 4 AAA ATPase domain Sigma54_activat PF00158.21 EEQ33500.1 - 0.00013 21.4 0.3 9.4 5.6 0.0 4.8 5 0 0 5 5 5 0 Sigma-54 interaction domain AAA_33 PF13671.1 EEQ33500.1 - 0.00013 21.8 16.3 0.29 11.0 0.0 5.9 6 0 0 6 6 4 3 AAA domain KaiC PF06745.8 EEQ33500.1 - 0.00014 21.0 0.4 3.4 6.7 0.0 4.4 4 0 0 4 4 4 1 KaiC Torsin PF06309.6 EEQ33500.1 - 0.00018 21.3 0.0 15 5.4 0.0 4.3 4 0 0 4 4 4 0 Torsin AAA_25 PF13481.1 EEQ33500.1 - 0.0015 17.9 6.0 5.8 6.2 0.0 4.9 5 0 0 5 5 4 1 AAA domain NACHT PF05729.7 EEQ33500.1 - 0.0016 18.1 2.5 10 5.7 0.0 4.3 4 0 0 4 4 4 0 NACHT domain DUF2075 PF09848.4 EEQ33500.1 - 0.005 15.8 0.0 0.005 15.8 0.0 7.2 9 2 0 9 9 6 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EEQ33500.1 - 8.4 6.0 11.8 4.6 6.9 0.0 4.7 6 0 0 6 6 4 0 NTPase LRR_4 PF12799.2 EEQ33503.1 - 1.1e-06 28.0 13.4 0.0031 17.0 0.3 5.2 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EEQ33503.1 - 7.5e-06 25.5 0.2 2.3e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 EEQ33503.1 - 3.5e-05 23.2 5.9 9.8 6.6 0.0 6.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.1 EEQ33503.1 - 0.0026 17.6 11.6 1.8 8.8 0.1 6.6 7 0 0 7 7 7 1 Leucine Rich repeat LRR_7 PF13504.1 EEQ33503.1 - 0.017 15.2 12.0 15 6.3 0.0 6.8 7 0 0 7 7 7 0 Leucine rich repeat LRR_8 PF13855.1 EEQ33503.1 - 0.031 14.0 15.3 0.032 13.9 0.6 4.7 4 0 0 4 4 4 0 Leucine rich repeat F-box PF00646.28 EEQ33503.1 - 0.041 13.5 1.5 0.4 10.3 0.8 2.8 2 1 0 2 2 2 0 F-box domain AA_permease_2 PF13520.1 EEQ33505.1 - 7.6e-57 192.7 50.2 9.8e-57 192.3 34.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ33505.1 - 1e-26 93.3 43.2 1.3e-26 92.9 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 EEQ33506.1 - 1.1e-47 162.6 0.0 4.9e-47 160.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 TFIIS_C PF01096.13 EEQ33508.1 - 2.9e-18 65.1 9.6 4.8e-18 64.5 1.7 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 EEQ33508.1 - 0.00029 20.7 6.9 0.9 9.5 0.2 3.5 3 1 0 3 3 3 2 Zinc ribbon domain Baculo_LEF5_C PF11792.3 EEQ33508.1 - 0.00073 18.8 9.1 0.00076 18.8 1.1 3.3 3 1 0 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.2 EEQ33508.1 - 0.001 18.8 9.0 0.0062 16.3 0.2 2.9 2 1 0 2 2 2 1 Double zinc ribbon C1_1 PF00130.17 EEQ33508.1 - 0.0021 17.7 0.3 0.0021 17.7 0.2 2.7 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_5 PF13719.1 EEQ33508.1 - 0.0031 17.0 12.0 0.026 14.1 0.6 4.0 4 0 0 4 4 4 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EEQ33508.1 - 0.0041 16.7 11.7 0.051 13.2 0.4 4.0 4 0 0 4 4 4 1 zinc-ribbon domain Terminase_GpA PF05876.7 EEQ33508.1 - 0.0051 15.2 3.0 0.0051 15.2 2.1 1.3 1 1 0 1 1 1 1 Phage terminase large subunit (GpA) RNA_POL_M_15KD PF02150.11 EEQ33508.1 - 0.011 15.4 8.1 1.1 9.0 0.6 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 EEQ33508.1 - 0.016 14.8 6.0 0.3 10.8 1.0 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 EEQ33508.1 - 0.037 13.6 9.9 0.16 11.6 0.1 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain tRNA-synt_1f PF01921.13 EEQ33508.1 - 0.052 12.2 0.1 0.056 12.1 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) zf-ribbon_3 PF13248.1 EEQ33508.1 - 0.2 10.8 6.5 11 5.3 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain DUF2296 PF10058.4 EEQ33508.1 - 0.31 10.8 5.7 1.3 8.8 1.0 2.8 2 1 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 EEQ33508.1 - 0.33 10.2 7.9 1.5 8.1 0.1 3.6 2 2 0 2 2 2 0 TFIIB zinc-binding RRN7 PF11781.3 EEQ33508.1 - 0.36 10.3 7.2 7.3 6.1 0.0 3.7 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF3797 PF12677.2 EEQ33508.1 - 0.43 10.2 4.3 0.7 9.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) Ribosomal_S27e PF01667.12 EEQ33508.1 - 0.65 9.5 11.4 5.3 6.6 1.4 3.6 2 2 0 2 2 2 0 Ribosomal protein S27 HypA PF01155.14 EEQ33508.1 - 0.77 9.4 9.7 2.4 7.8 1.8 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family RNHCP PF12647.2 EEQ33508.1 - 0.84 9.5 9.9 7.8 6.4 0.1 3.4 1 1 0 2 2 2 0 RNHCP domain RPA_interact_C PF14768.1 EEQ33508.1 - 1.1 9.7 7.7 9.6 6.6 5.3 2.2 1 1 0 1 1 1 0 Replication protein A interacting C-terminal Ribosomal_L44 PF00935.14 EEQ33508.1 - 1.1 9.2 3.8 18 5.4 0.1 3.2 3 0 0 3 3 3 0 Ribosomal protein L44 Rpr2 PF04032.11 EEQ33508.1 - 1.5 8.7 9.0 90 3.0 6.3 2.6 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1610 PF07754.6 EEQ33508.1 - 1.6 8.9 7.8 3.1 7.9 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1610) zinc_ribbon_2 PF13240.1 EEQ33508.1 - 1.8 8.1 9.4 1.4 8.5 0.1 3.6 3 1 0 3 3 3 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EEQ33508.1 - 1.9 8.0 11.8 3.6 7.1 0.2 3.3 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Lar_restr_allev PF14354.1 EEQ33508.1 - 1.9 8.8 10.9 9.1 6.6 1.7 3.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-LITAF-like PF10601.4 EEQ33508.1 - 2.7 7.8 10.0 2.5 8.0 0.1 3.7 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain eIF-5_eIF-2B PF01873.12 EEQ33508.1 - 3.3 7.3 7.5 17 5.0 0.2 3.1 2 1 0 3 3 3 0 Domain found in IF2B/IF5 Nudix_N_2 PF14803.1 EEQ33508.1 - 4.9 6.9 10.3 10 5.8 0.1 3.7 4 0 0 4 4 4 0 Nudix N-terminal Desulfoferrod_N PF06397.7 EEQ33508.1 - 4.9 6.6 6.1 16 4.9 0.2 3.1 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain Tnp_zf-ribbon_2 PF13842.1 EEQ33508.1 - 5.3 7.5 7.1 3.8 8.0 0.0 3.4 4 0 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.11 EEQ33508.1 - 6.3 6.9 11.4 2.1 8.5 0.1 3.6 4 0 0 4 4 4 0 C1 domain DUF4379 PF14311.1 EEQ33508.1 - 7.8 6.3 8.5 2.3 8.1 2.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4379) C1_4 PF07975.7 EEQ33508.1 - 8.3 6.5 10.7 8.1 6.5 0.1 3.2 2 1 1 3 3 3 0 TFIIH C1-like domain UPF0547 PF10571.4 EEQ33508.1 - 9.6 6.0 14.6 0.8 9.4 0.5 3.7 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 BSD PF03909.12 EEQ33509.1 - 1e-24 86.0 5.0 1.7e-13 50.0 0.6 3.0 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EEQ33509.1 - 4.6e-18 64.6 0.0 1e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain TetR PF13972.1 EEQ33509.1 - 0.013 14.9 0.1 0.12 11.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial transcriptional repressor DUF1751 PF08551.5 EEQ33510.1 - 0.0014 18.9 1.9 0.002 18.4 0.4 2.0 1 1 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) PHD PF00628.24 EEQ33511.1 - 1e-09 37.9 7.0 1.6e-09 37.2 4.8 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EEQ33511.1 - 1.1e-08 35.2 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.1 EEQ33511.1 - 0.14 11.4 2.8 0.24 10.7 1.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.1 EEQ33511.1 - 0.38 10.9 2.1 0.79 9.9 1.5 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Transket_pyr PF02779.19 EEQ33512.1 - 7.9e-66 220.9 0.0 1.4e-65 220.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EEQ33512.1 - 5.3e-55 186.2 0.0 7.3e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2247 PF10004.4 EEQ33512.1 - 0.036 13.7 0.1 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF1162 PF06650.7 EEQ33513.1 - 9.7e-86 287.4 0.1 7.6e-84 281.1 0.0 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EEQ33513.1 - 9.8e-42 141.2 0.0 3.3e-41 139.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EEQ33513.1 - 1.5e-05 25.0 0.0 6.3e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 ATG C terminal domain DUF3429 PF11911.3 EEQ33515.1 - 3.3e-41 140.5 10.8 4.8e-41 140.0 7.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.11 EEQ33516.1 - 7.4e-71 237.8 0.3 1.7e-70 236.6 0.2 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEQ33516.1 - 3.1e-57 193.7 0.0 4.3e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Peptidase_M41 PF01434.13 EEQ33519.1 - 1.2e-63 214.4 0.1 2.1e-63 213.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EEQ33519.1 - 8.6e-43 145.6 0.0 1.9e-42 144.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ33519.1 - 3.2e-06 27.2 0.1 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 EEQ33519.1 - 5.2e-06 27.2 0.0 1.7e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ33519.1 - 3.4e-05 23.6 0.0 9.7e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EEQ33519.1 - 4.2e-05 22.4 0.2 9.3e-05 21.3 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 EEQ33519.1 - 0.00022 21.3 2.7 0.0036 17.4 0.2 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEQ33519.1 - 0.00095 18.2 0.0 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EEQ33519.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EEQ33519.1 - 0.0018 18.1 0.0 0.0075 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EEQ33519.1 - 0.0021 17.9 0.0 0.0074 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EEQ33519.1 - 0.0023 17.6 0.3 0.0083 15.8 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EEQ33519.1 - 0.0025 17.2 1.3 0.12 11.8 0.2 2.4 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEQ33519.1 - 0.0075 15.3 0.3 0.023 13.7 0.2 1.8 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EEQ33519.1 - 0.0079 16.0 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEQ33519.1 - 0.012 15.5 0.0 0.035 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ33519.1 - 0.015 15.5 0.0 0.044 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EEQ33519.1 - 0.019 14.1 0.3 0.036 13.2 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EEQ33519.1 - 0.021 14.4 0.3 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 EEQ33519.1 - 0.027 13.4 0.0 0.061 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 EEQ33519.1 - 0.029 13.4 0.1 1.2 8.1 0.0 2.6 3 0 0 3 3 3 0 KaiC NTP_transferase PF00483.18 EEQ33521.1 - 1.6e-47 161.9 0.0 2.9e-47 161.0 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EEQ33521.1 - 3.2e-17 61.1 19.8 3.5e-10 38.9 1.2 4.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEQ33521.1 - 1.5e-09 38.0 0.0 2.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EEQ33521.1 - 4.9e-07 29.1 1.3 4.9e-07 29.1 0.9 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EEQ33521.1 - 0.091 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF3357 PF11837.3 EEQ33522.1 - 0.0016 18.2 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Mucin PF01456.12 EEQ33522.1 - 0.0088 15.8 7.8 0.019 14.7 5.4 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein LAT PF15234.1 EEQ33522.1 - 0.02 14.3 4.5 0.083 12.3 1.1 2.1 2 0 0 2 2 2 0 Linker for activation of T-cells DUF3328 PF11807.3 EEQ33522.1 - 0.07 12.8 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Mid2 PF04478.7 EEQ33522.1 - 0.65 9.4 3.4 0.35 10.2 0.1 2.0 1 1 0 2 2 2 0 Mid2 like cell wall stress sensor DUF4366 PF14283.1 EEQ33522.1 - 1.8 7.8 3.6 0.43 9.9 0.2 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Fic PF02661.13 EEQ33524.1 - 4.4e-10 40.1 0.9 9.4e-10 39.0 0.6 1.6 1 0 0 1 1 1 1 Fic/DOC family zf-C2H2 PF00096.21 EEQ33525.1 - 1.6e-15 56.4 38.9 0.00028 21.0 1.0 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ33525.1 - 8e-14 51.1 35.3 5e-07 29.6 0.3 5.6 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ33525.1 - 0.0008 19.5 38.3 0.04 14.2 2.0 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger Suf PF05843.9 EEQ33525.1 - 1.9 8.1 8.4 2.8 7.5 5.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 EEQ33525.1 - 2.1 8.1 15.6 3.1 7.5 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EEQ33525.1 - 3.4 5.8 32.0 5.1 5.2 22.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suc_Fer-like PF06999.7 EEQ33526.1 - 1.8e-33 116.5 0.0 5e-33 115.0 0.0 1.7 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Opiods_neuropep PF01160.13 EEQ33526.1 - 0.59 9.9 2.6 0.43 10.3 0.4 1.8 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide DUF4129 PF13559.1 EEQ33527.1 - 0.0031 17.4 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) DUF4389 PF14333.1 EEQ33527.1 - 1 9.1 3.2 2.1 8.1 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) GCFC PF07842.7 EEQ33528.1 - 2.2e-85 286.3 8.4 3.5e-85 285.7 5.8 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EEQ33528.1 - 8.9e-16 57.4 0.4 1.7e-15 56.5 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEQ33528.1 - 7.6e-07 28.8 0.4 7.6e-07 28.8 0.3 2.3 3 0 0 3 3 3 1 DExH-box splicing factor binding site ATP-synt_E PF05680.7 EEQ33528.1 - 0.039 13.8 1.5 0.14 12.0 1.1 1.9 1 0 0 1 1 1 0 ATP synthase E chain Sod_Fe_C PF02777.13 EEQ33529.1 - 2.9e-37 126.7 0.2 4.8e-37 126.0 0.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EEQ33529.1 - 5.1e-30 103.5 1.0 8.1e-30 102.9 0.7 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Spc7 PF08317.6 EEQ33530.1 - 0.46 9.0 14.8 0.72 8.4 10.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EEQ33530.1 - 1.1 8.2 15.4 1.9 7.4 10.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 RP-C_C PF11800.3 EEQ33530.1 - 1.2 8.7 12.5 0.085 12.5 4.5 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Microtub_assoc PF07989.6 EEQ33530.1 - 2.1 8.2 15.8 2.4 8.0 3.9 2.6 1 1 1 2 2 2 0 Microtubule associated DUF3584 PF12128.3 EEQ33530.1 - 3.6 4.7 19.9 5 4.3 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_23 PF13476.1 EEQ33530.1 - 5.9 7.1 11.1 10 6.3 7.7 1.3 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 EEQ33530.1 - 9.4 6.6 15.0 13 6.1 9.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Sld5 PF05916.6 EEQ33531.1 - 4.3e-16 59.1 0.0 5.3e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein PH_10 PF15411.1 EEQ33536.1 - 6.2e-35 119.8 0.1 1.6e-30 105.6 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain CDC24 PF06395.6 EEQ33536.1 - 1.3e-34 118.1 0.0 2.4e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EEQ33536.1 - 3.1e-29 102.1 1.1 5.8e-29 101.2 0.7 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EEQ33536.1 - 1.6e-07 30.9 0.0 3.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.27 EEQ33537.1 - 2.1e-40 135.1 13.7 1.2e-06 28.2 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EEQ33537.1 - 5.1e-12 45.3 0.2 1.1e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ33537.1 - 8.4e-08 31.6 0.0 2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 EEQ33537.1 - 0.00049 19.8 0.2 4.2 7.1 0.0 4.1 3 2 1 4 4 4 3 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EEQ33537.1 - 0.0044 15.2 0.4 0.23 9.5 0.1 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Uds1 PF15456.1 EEQ33539.1 - 1.1e-40 138.5 3.9 1.1e-40 138.5 2.7 6.5 6 2 1 7 7 7 2 Up-regulated During Septation TPR_MLP1_2 PF07926.7 EEQ33539.1 - 0.0073 16.0 0.6 0.0073 16.0 0.4 7.4 6 1 0 7 7 7 2 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EEQ33539.1 - 2.9 7.7 68.8 0.016 14.9 5.7 9.1 9 1 1 10 10 10 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 EEQ33539.1 - 7.7 6.3 21.6 0.65 9.8 1.5 5.3 2 2 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.11 EEQ33540.1 - 3.4e-27 95.0 33.9 5.1e-27 94.5 23.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UCR_hinge PF02320.11 EEQ33541.1 - 1.4e-23 82.6 4.2 2.9e-23 81.5 2.9 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 EEQ33541.1 - 0.014 14.9 8.5 0.016 14.8 5.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.7 EEQ33541.1 - 0.024 13.7 8.9 0.026 13.6 6.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YqfQ PF14181.1 EEQ33541.1 - 0.11 12.5 1.8 0.11 12.5 1.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein Fmp27_WPPW PF10359.4 EEQ33541.1 - 0.15 10.4 2.9 0.17 10.2 2.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spore_coat_CotO PF14153.1 EEQ33541.1 - 0.17 11.3 8.1 0.18 11.2 5.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO TRAP_alpha PF03896.11 EEQ33541.1 - 0.17 10.8 9.2 0.19 10.7 6.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.6 EEQ33541.1 - 0.18 9.8 3.8 0.2 9.7 2.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP90 PF00183.13 EEQ33541.1 - 0.26 9.6 9.0 0.27 9.5 6.2 1.0 1 0 0 1 1 1 0 Hsp90 protein Daxx PF03344.10 EEQ33541.1 - 0.29 9.5 15.9 0.32 9.4 11.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EEQ33541.1 - 0.42 9.9 9.0 0.52 9.6 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GOLD_2 PF13897.1 EEQ33541.1 - 0.57 10.4 2.5 0.68 10.1 1.7 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FAM176 PF14851.1 EEQ33541.1 - 0.61 9.7 5.4 0.8 9.3 3.7 1.4 1 0 0 1 1 1 0 FAM176 family DUF2722 PF10846.3 EEQ33541.1 - 0.62 9.0 3.9 0.68 8.9 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) VID27 PF08553.5 EEQ33541.1 - 0.71 8.0 8.5 0.78 7.8 5.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein TLP-20 PF06088.6 EEQ33541.1 - 0.85 9.2 3.2 1.1 8.9 2.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nop14 PF04147.7 EEQ33541.1 - 1.2 6.9 13.1 1.3 6.8 9.1 1.0 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.7 EEQ33541.1 - 1.5 7.4 11.7 1.7 7.3 8.1 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.9 EEQ33541.1 - 1.5 6.7 7.5 1.6 6.6 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 EEQ33541.1 - 1.7 7.1 6.3 1.9 7.0 4.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3530 PF12048.3 EEQ33541.1 - 1.7 7.5 8.5 2 7.3 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF3306 PF11748.3 EEQ33541.1 - 1.7 9.3 7.8 2.2 8.9 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Paf1 PF03985.8 EEQ33541.1 - 3.8 6.1 10.1 4.1 6.0 7.0 1.1 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.7 EEQ33541.1 - 4.8 6.3 11.9 5.1 6.2 8.2 1.1 1 0 0 1 1 1 0 SDA1 DUF2890 PF11081.3 EEQ33541.1 - 5.1 7.1 17.3 6.2 6.8 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF3381 PF11861.3 EEQ33541.1 - 5.6 6.4 10.8 8 5.9 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PBP1_TM PF14812.1 EEQ33541.1 - 5.6 7.3 8.0 8.9 6.6 5.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EEQ33541.1 - 7.7 6.0 17.2 13 5.2 11.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin WWbp PF10349.4 EEQ33542.1 - 3.3e-19 69.8 2.9 3.3e-19 69.8 2.0 2.0 2 0 0 2 2 2 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EEQ33542.1 - 8.8e-05 22.2 0.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EEQ33542.1 - 0.0092 15.4 0.0 0.03 13.8 0.0 1.8 1 1 0 1 1 1 1 GRAM domain Acyltransferase PF01553.16 EEQ33544.1 - 1.3e-10 40.8 0.0 0.00013 21.4 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase Prenyltransf PF01255.14 EEQ33545.1 - 1.5e-82 276.0 0.0 2.3e-82 275.4 0.0 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Saccharop_dh PF03435.13 EEQ33546.1 - 3.7e-112 375.1 0.4 1e-110 370.4 0.3 2.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EEQ33546.1 - 5.6e-06 26.4 0.3 9.6e-06 25.7 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EEQ33546.1 - 1.2e-05 25.4 0.9 0.0035 17.3 0.1 2.2 2 0 0 2 2 2 2 NADH(P)-binding NAD_binding_7 PF13241.1 EEQ33546.1 - 0.015 15.5 0.1 0.032 14.4 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2325 PF10087.4 EEQ33546.1 - 0.029 14.1 0.1 0.12 12.2 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) 3Beta_HSD PF01073.14 EEQ33546.1 - 0.069 11.8 0.1 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N_2 PF13602.1 EEQ33547.1 - 1.1e-22 81.3 0.0 1.8e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEQ33547.1 - 2e-14 53.2 0.3 3.3e-14 52.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EEQ33547.1 - 0.0044 17.0 0.1 0.0077 16.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding TOBE PF03459.12 EEQ33547.1 - 0.062 13.4 0.0 6 7.0 0.0 2.6 2 0 0 2 2 2 0 TOBE domain Glyco_hydro_15 PF00723.16 EEQ33548.1 - 3.6e-92 309.2 0.1 4.4e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EEQ33548.1 - 3.6e-28 97.0 0.1 7.3e-28 96.0 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Aha1_N PF09229.6 EEQ33549.1 - 5.4e-35 120.1 1.4 1.5e-34 118.7 1.0 1.7 1 1 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EEQ33549.1 - 6.8e-17 61.7 0.2 1.4e-16 60.7 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.12 EEQ33549.1 - 0.48 10.2 19.0 0.83 9.4 13.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein FBPase PF00316.15 EEQ33551.1 - 2.3e-116 388.1 0.0 2.7e-116 387.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase OAD_gamma PF04277.8 EEQ33552.1 - 0.039 14.3 0.7 0.091 13.1 0.1 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF912 PF06024.7 EEQ33552.1 - 0.13 12.3 1.0 0.25 11.4 0.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Fungal_trans_2 PF11951.3 EEQ33553.1 - 4.7e-38 130.8 2.6 5.9e-38 130.4 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ33553.1 - 1.9e-07 30.8 11.1 3e-07 30.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.15 EEQ33554.1 - 1.4e-64 217.2 2.2 3.1e-64 216.1 1.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ33554.1 - 2.3e-31 109.9 0.0 6.3e-30 105.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ33554.1 - 5e-17 61.6 0.0 1.6e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ33554.1 - 1.5e-14 54.6 0.0 2.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EEQ33554.1 - 2.3e-14 53.3 0.3 2.3e-14 53.3 0.2 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 EEQ33554.1 - 4.7e-12 45.2 0.5 8.8e-12 44.3 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEQ33554.1 - 0.00024 20.7 0.6 0.0035 16.9 0.8 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HlyIII PF03006.15 EEQ33555.1 - 1.1e-20 74.0 11.1 1.1e-20 73.9 7.3 1.3 1 1 0 1 1 1 1 Haemolysin-III related Sugar_tr PF00083.19 EEQ33556.1 - 8.2e-80 268.5 28.3 9.9e-80 268.3 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ33556.1 - 1.2e-23 83.3 46.1 2.1e-17 62.9 12.4 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ33556.1 - 0.002 16.4 3.3 0.002 16.4 2.3 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MttA_Hcf106 PF02416.11 EEQ33556.1 - 0.19 10.8 0.9 0.53 9.4 0.6 1.7 1 0 0 1 1 1 0 mttA/Hcf106 family V_ATPase_I PF01496.14 EEQ33557.1 - 3.5e-286 951.0 0.6 4e-286 950.8 0.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 EEQ33557.1 - 0.015 15.0 0.1 0.044 13.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CheZ PF04344.8 EEQ33557.1 - 0.019 14.6 0.7 0.76 9.3 0.0 2.4 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Filament PF00038.16 EEQ33557.1 - 0.15 11.4 7.5 2.3 7.6 0.1 2.6 2 1 0 2 2 2 0 Intermediate filament protein DUF3552 PF12072.3 EEQ33557.1 - 0.26 10.4 3.9 5.8 6.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) IncA PF04156.9 EEQ33557.1 - 0.6 9.6 5.7 1 8.9 2.3 2.3 2 0 0 2 2 2 0 IncA protein YlqD PF11068.3 EEQ33557.1 - 0.74 9.8 3.6 1.6 8.7 0.5 2.5 2 1 1 3 3 3 0 YlqD protein DUF342 PF03961.8 EEQ33557.1 - 1.5 7.1 3.8 0.79 8.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF2888 PF11135.3 EEQ33558.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) DUF3437 PF11919.3 EEQ33559.1 - 2.3e-31 107.3 0.0 7.5e-31 105.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EEQ33559.1 - 0.00033 20.4 0.1 0.97 9.6 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.3 EEQ33559.1 - 0.022 14.1 1.8 4.7 6.4 0.1 3.9 4 1 0 4 4 4 0 CLASP N terminal Mannosyl_trans2 PF04188.8 EEQ33560.1 - 1.3e-32 113.2 13.5 8.1e-26 90.9 3.2 2.1 2 0 0 2 2 2 2 Mannosyltransferase (PIG-V)) Pro_CA PF00484.14 EEQ33563.1 - 2.2e-43 147.9 0.1 2.7e-43 147.6 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Velvet PF11754.3 EEQ33565.1 - 4.9e-56 189.5 0.3 4e-55 186.5 0.2 2.0 1 1 0 1 1 1 1 Velvet factor DUF736 PF05284.7 EEQ33566.1 - 0.00067 19.4 0.0 0.00086 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF736) MOZ_SAS PF01853.13 EEQ33568.1 - 1.3e-78 262.6 0.0 1.8e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family HTH_45 PF14947.1 EEQ33568.1 - 0.081 12.7 0.1 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix PetG PF02529.10 EEQ33569.1 - 0.027 13.9 0.1 0.048 13.1 0.1 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Acetyltransf_2 PF00797.12 EEQ33570.1 - 2.9e-41 141.6 0.0 4e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Methyltransf_6 PF03737.10 EEQ33571.1 - 2.8e-24 85.7 0.0 4.9e-24 84.9 0.0 1.3 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase Thiolase_N PF00108.18 EEQ33572.1 - 6.8e-79 264.5 1.9 6.8e-79 264.5 1.3 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEQ33572.1 - 1.8e-43 146.8 0.1 3.9e-43 145.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEQ33572.1 - 0.013 15.0 0.5 0.084 12.3 0.3 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ODV-E18 PF10717.4 EEQ33573.1 - 0.052 12.9 0.7 0.12 11.8 0.4 1.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 SR-25 PF10500.4 EEQ33573.1 - 0.59 9.5 4.1 0.79 9.1 2.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GFO_IDH_MocA PF01408.17 EEQ33574.1 - 2.8e-19 69.7 0.0 6.8e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold APH PF01636.18 EEQ33575.1 - 7.5e-10 38.9 0.9 1.3e-08 34.9 0.7 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ33575.1 - 4e-05 23.2 0.0 7.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EEQ33575.1 - 0.049 12.6 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Potyvirid-P3 PF13608.1 EEQ33575.1 - 0.13 11.3 0.3 0.19 10.7 0.2 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Drf_GBD PF06371.8 EEQ33576.1 - 2.9e-18 65.9 4.6 2.2e-16 59.7 3.2 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain CRM1_C PF08767.6 EEQ33576.1 - 0.01 14.7 0.1 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 CRM1 C terminal Snf7 PF03357.16 EEQ33577.1 - 6.5e-44 149.3 10.0 7.8e-44 149.0 6.9 1.1 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EEQ33577.1 - 0.00086 18.7 5.5 0.00088 18.7 2.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) DUF1395 PF07160.7 EEQ33577.1 - 0.0046 16.4 4.0 0.064 12.7 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1395) NPV_P10 PF05531.7 EEQ33577.1 - 0.017 15.3 6.6 0.4 10.9 1.6 2.6 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 EEQ33577.1 - 0.027 13.8 7.4 0.1 11.8 3.4 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.4 EEQ33577.1 - 0.048 13.5 6.1 0.2 11.5 3.1 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EEQ33577.1 - 0.05 13.1 3.4 1.9 8.0 0.2 2.2 1 1 0 2 2 2 0 IncA protein Mod_r PF07200.8 EEQ33577.1 - 0.074 12.9 5.6 0.052 13.4 1.9 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HHH_2 PF12826.2 EEQ33577.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4140 PF13600.1 EEQ33577.1 - 0.096 13.1 2.7 0.99 9.8 0.0 3.0 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 EEQ33577.1 - 0.11 11.3 5.6 0.16 10.8 3.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 EEQ33577.1 - 0.14 11.8 4.2 6.7 6.3 0.0 3.3 2 1 3 5 5 5 0 Prefoldin subunit Reo_sigmaC PF04582.7 EEQ33577.1 - 0.19 10.8 3.7 0.84 8.7 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Sec34 PF04136.10 EEQ33577.1 - 0.2 11.3 4.1 0.49 10.0 1.5 2.0 1 1 0 2 2 2 0 Sec34-like family PqqD PF05402.7 EEQ33577.1 - 0.22 11.5 1.0 0.43 10.6 0.6 1.6 1 1 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Prefoldin_2 PF01920.15 EEQ33577.1 - 0.27 11.0 7.3 1 9.1 0.0 3.5 2 1 1 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.4 EEQ33577.1 - 0.48 10.5 6.4 4.3 7.5 0.5 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4337 PF14235.1 EEQ33577.1 - 0.74 9.6 6.2 0.31 10.8 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Laminin_II PF06009.7 EEQ33577.1 - 1.1 8.9 4.8 1.7 8.3 0.6 2.2 1 1 0 2 2 2 0 Laminin Domain II OmpH PF03938.9 EEQ33577.1 - 4.3 7.2 13.2 2.6e+02 1.4 9.3 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FliD_N PF02465.13 EEQ33577.1 - 6.8 7.1 7.8 13 6.2 0.4 2.8 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus SAPS PF04499.10 EEQ33578.1 - 1e-175 584.9 0.4 1e-175 584.9 0.3 1.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Complex1_51K PF01512.12 EEQ33580.1 - 2.4e-48 163.6 0.0 4e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EEQ33580.1 - 5.1e-18 63.9 1.7 5.1e-18 63.9 1.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EEQ33580.1 - 1.9e-09 37.2 0.0 7.3e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 SLBB domain TSA PF03249.8 EEQ33580.1 - 0.45 9.0 3.1 0.74 8.2 2.1 1.2 1 0 0 1 1 1 0 Type specific antigen Nup96 PF12110.3 EEQ33581.1 - 1.4e-84 283.6 0.0 2e-84 283.1 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EEQ33581.1 - 1.2e-48 164.5 0.0 1.9e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EEQ33581.1 - 6.5e-11 42.4 150.4 2e-09 37.6 29.3 11.4 5 2 4 9 9 9 3 Nucleoporin FG repeat region AMP-binding PF00501.23 EEQ33582.1 - 2.4e-92 309.5 0.0 3e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ33582.1 - 5.9e-23 81.6 0.8 2.4e-20 73.2 0.7 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GET2 PF08690.5 EEQ33583.1 - 1e-05 24.9 1.2 1.5e-05 24.4 0.8 1.3 1 1 0 1 1 1 1 GET complex subunit GET2 PAT1 PF09770.4 EEQ33583.1 - 3.9 5.5 8.9 4.4 5.4 6.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 C2 PF00168.25 EEQ33584.1 - 9.7e-22 76.6 0.0 1.1e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain IMS PF00817.15 EEQ33586.1 - 7.1e-39 132.9 0.0 1.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EEQ33586.1 - 1.6e-08 34.5 0.4 5.5e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Reprolysin_4 PF13583.1 EEQ33587.1 - 4.8e-64 215.6 1.8 8e-64 214.9 1.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EEQ33587.1 - 1.2e-58 198.3 6.5 1.2e-58 198.3 4.5 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EEQ33587.1 - 1.7e-41 142.1 1.9 1.7e-41 142.1 1.3 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EEQ33587.1 - 6e-19 68.7 0.3 9.5e-18 64.9 0.2 2.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EEQ33587.1 - 6.3e-17 61.5 35.1 6.3e-17 61.5 24.4 4.3 3 2 1 4 4 4 1 Disintegrin SKG6 PF08693.5 EEQ33587.1 - 0.017 14.4 0.7 0.035 13.4 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1191 PF06697.7 EEQ33587.1 - 0.024 13.4 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Pep_M12B_propep PF01562.14 EEQ33587.1 - 0.052 13.3 0.1 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Reprolysin family propeptide Mid2 PF04478.7 EEQ33587.1 - 0.084 12.2 0.2 0.19 11.1 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EF-hand_7 PF13499.1 EEQ33588.1 - 6.2e-15 55.0 0.7 1.3e-08 34.8 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEQ33588.1 - 2.3e-14 51.5 2.0 5.7e-05 22.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EEQ33588.1 - 1.5e-13 49.3 5.3 6.9e-06 25.5 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EEQ33588.1 - 8.1e-12 44.5 1.3 2.4e-09 36.6 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 EEQ33588.1 - 0.0069 16.1 0.0 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 EEQ33588.1 - 0.019 14.3 5.0 0.66 9.4 0.1 2.8 3 0 0 3 3 3 0 EF hand DUF3323 PF11796.3 EEQ33588.1 - 0.072 12.4 0.6 0.17 11.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) EFhand_Ca_insen PF08726.5 EEQ33588.1 - 0.13 12.2 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand MgsA_C PF12002.3 EEQ33589.1 - 3.9e-58 195.8 0.1 7e-58 195.0 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EEQ33589.1 - 5.5e-11 42.7 0.1 1.4e-10 41.4 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEQ33589.1 - 2e-08 33.5 0.0 5.2e-07 28.9 0.0 2.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EEQ33589.1 - 0.00057 19.5 0.1 0.0021 17.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEQ33589.1 - 0.022 14.2 0.0 0.1 12.0 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 EEQ33589.1 - 0.029 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEQ33589.1 - 0.029 13.5 0.0 0.072 12.2 0.0 1.6 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Aminotran_1_2 PF00155.16 EEQ33591.1 - 1.7e-65 221.3 0.0 2e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEQ33591.1 - 0.011 14.8 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEQ33591.1 - 0.039 12.9 0.0 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family KH_1 PF00013.24 EEQ33592.1 - 3.4e-41 138.6 6.7 1.8e-13 49.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EEQ33592.1 - 5.1e-32 108.9 7.6 2.1e-10 40.0 0.1 3.8 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EEQ33592.1 - 9.8e-13 47.4 1.5 0.00085 18.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EEQ33592.1 - 1.9e-08 33.8 3.6 0.11 12.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EEQ33592.1 - 0.0003 20.5 3.3 4.7 7.0 0.1 3.5 3 0 0 3 3 3 3 NusA-like KH domain DUF2763 PF10961.3 EEQ33592.1 - 0.0081 16.5 0.1 0.0081 16.5 0.0 5.4 4 2 2 6 6 6 1 Protein of unknown function (DUF2763) CDC45 PF02724.9 EEQ33592.1 - 6.2 4.7 9.2 10 3.9 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Amidoligase_2 PF12224.3 EEQ33593.1 - 1.3e-19 70.8 0.0 1.6e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme HHH_3 PF12836.2 EEQ33594.1 - 0.0033 17.3 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif DUF202 PF02656.10 EEQ33595.1 - 2.5 8.3 6.7 4.2 7.6 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Ald_Xan_dh_C2 PF02738.13 EEQ33596.1 - 2.5e-197 656.5 0.2 3.3e-197 656.1 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EEQ33596.1 - 1.8e-46 157.7 0.0 3.1e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EEQ33596.1 - 9.8e-33 112.1 0.1 4.4e-32 110.0 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EEQ33596.1 - 7.8e-28 96.2 0.0 1.8e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 EEQ33596.1 - 1.2e-27 96.1 0.0 3.3e-27 94.7 0.0 1.8 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 EEQ33596.1 - 3.2e-08 33.1 0.4 8.5e-08 31.8 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.11 EEQ33596.1 - 0.038 13.8 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-70 region 3 AMP-binding PF00501.23 EEQ33597.1 - 2.1e-74 250.4 0.0 3e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEQ33597.1 - 7.6e-70 234.6 0.0 1.1e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EEQ33597.1 - 6.9e-12 45.3 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EEQ33597.1 - 1.8e-11 44.0 0.0 5e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ33597.1 - 2.1e-07 31.7 0.0 6.5e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EEQ33597.1 - 0.002 16.8 0.0 0.0053 15.4 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 EEQ33597.1 - 0.0054 15.6 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 Condensation domain RmlD_sub_bind PF04321.12 EEQ33597.1 - 0.028 13.3 0.0 0.19 10.5 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain AAA_17 PF13207.1 EEQ33598.1 - 1.9e-05 25.4 0.0 3.8e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EEQ33598.1 - 8.4e-05 22.2 0.0 0.00012 21.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EEQ33598.1 - 0.00011 22.4 0.0 0.0015 18.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEQ33598.1 - 0.0042 17.3 0.1 0.0098 16.1 0.0 1.6 1 1 0 1 1 1 1 ABC transporter KTI12 PF08433.5 EEQ33598.1 - 0.038 13.1 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.1 EEQ33598.1 - 0.074 13.0 0.2 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EEQ33598.1 - 0.078 12.9 0.6 0.2 11.6 0.4 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EEQ33598.1 - 0.092 12.6 1.8 0.67 9.8 0.7 2.2 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 EEQ33598.1 - 0.13 11.0 0.7 0.35 9.6 0.2 1.9 1 1 1 2 2 2 0 NB-ARC domain SNF2_N PF00176.18 EEQ33599.1 - 3.1e-34 118.1 0.0 5.1e-30 104.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ33599.1 - 0.00012 21.8 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HMG_box PF00505.14 EEQ33600.1 - 2.1e-21 75.9 0.0 3.8e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEQ33600.1 - 2.4e-05 24.6 0.0 4.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DUF2502 PF10697.4 EEQ33600.1 - 0.038 14.0 0.3 0.079 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) Ribosomal_S6e PF01092.14 EEQ33601.1 - 2.6e-59 198.4 0.1 5.2e-59 197.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e DUF2992 PF11208.3 EEQ33601.1 - 0.48 10.3 9.1 0.73 9.7 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Pribosyltran_N PF13793.1 EEQ33602.1 - 1.4e-46 156.9 0.5 1.3e-44 150.6 0.1 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEQ33602.1 - 2e-44 151.5 1.3 5.3e-37 127.3 0.3 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEQ33602.1 - 2.1e-14 53.2 0.5 2.5e-13 49.8 0.2 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEQ33602.1 - 0.0063 15.7 0.1 0.012 14.8 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.7 EEQ33603.1 - 4.8e-132 440.2 0.0 4.8e-132 440.2 0.0 3.7 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EEQ33603.1 - 1.3e-83 280.8 0.0 2.3e-83 279.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EEQ33603.1 - 7.5e-81 271.9 3.0 7.5e-81 271.9 2.1 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EEQ33603.1 - 3.8e-33 113.6 9.4 3.8e-33 113.6 6.5 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 EEQ33603.1 - 0.00098 18.9 0.0 0.0026 17.5 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain NARP1 PF12569.3 EEQ33603.1 - 1.3 7.7 15.0 3.6 6.2 10.4 1.7 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 An_peroxidase PF03098.10 EEQ33604.1 - 1.6e-88 297.3 0.0 1.7e-75 254.3 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 EEQ33604.1 - 1.3e-07 30.5 0.0 9.2e-06 24.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Steroid_dh PF02544.11 EEQ33605.1 - 1.6e-31 109.0 0.2 2.1e-31 108.7 0.2 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EEQ33605.1 - 7.8e-07 28.6 0.4 1.1e-06 28.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EEQ33605.1 - 3.3e-06 27.1 0.3 7.1e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Hema_stalk PF08720.5 EEQ33605.1 - 0.16 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk Halogen_Hydrol PF10112.4 EEQ33605.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Glyco_transf_34 PF05637.7 EEQ33606.1 - 2e-58 197.7 0.0 2.7e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EEQ33606.1 - 0.063 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Ribosomal_L28 PF00830.14 EEQ33607.1 - 4.1e-18 64.9 0.4 7.4e-18 64.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L28 family DUF4582 PF15189.1 EEQ33607.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) TIP49 PF06068.8 EEQ33608.1 - 3.7e-186 618.6 0.1 4.3e-186 618.4 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EEQ33608.1 - 1.9e-11 44.3 0.3 2.5e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEQ33608.1 - 3.4e-11 42.6 0.9 4.6e-07 29.1 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEQ33608.1 - 5.1e-06 26.5 0.0 0.012 15.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EEQ33608.1 - 1.1e-05 25.5 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EEQ33608.1 - 9.7e-05 22.0 0.1 0.00027 20.6 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EEQ33608.1 - 0.00018 21.4 0.1 0.00042 20.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ33608.1 - 0.00083 19.0 0.2 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEQ33608.1 - 0.0011 18.1 0.1 0.0027 16.8 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EEQ33608.1 - 0.0016 17.9 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EEQ33608.1 - 0.0016 17.8 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEQ33608.1 - 0.012 14.7 0.6 0.065 12.3 0.0 2.3 3 0 0 3 3 3 0 KaiC Mg_chelatase PF01078.16 EEQ33608.1 - 0.015 14.4 0.1 0.72 8.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 EEQ33608.1 - 0.02 13.8 0.0 0.04 12.7 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.12 EEQ33608.1 - 0.023 14.1 0.1 0.047 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 EEQ33608.1 - 0.026 13.5 0.1 0.057 12.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EEQ33608.1 - 0.031 14.5 0.3 0.24 11.7 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 EEQ33608.1 - 0.054 14.3 0.0 0.16 12.8 0.0 1.9 2 1 0 2 2 1 0 AAA domain DNA_pol3_delta PF06144.8 EEQ33608.1 - 0.087 12.3 0.2 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Fungal_trans PF04082.13 EEQ33609.1 - 3.3e-17 62.2 0.3 4.5e-17 61.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-SNARE PF05008.10 EEQ33611.1 - 5.6e-23 80.8 7.1 5.6e-23 80.8 4.9 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EEQ33611.1 - 1.2e-15 57.2 2.2 1.2e-15 57.2 1.5 2.8 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.13 EEQ33611.1 - 0.0027 15.8 1.9 0.21 9.6 0.1 2.2 2 0 0 2 2 2 2 Fusion glycoprotein F0 Sec20 PF03908.8 EEQ33611.1 - 0.012 15.2 2.7 0.035 13.8 0.1 2.4 2 2 0 2 2 2 0 Sec20 DUF106 PF01956.11 EEQ33611.1 - 0.021 14.3 0.1 0.52 9.8 0.0 2.2 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF825 PF05695.7 EEQ33611.1 - 0.03 11.7 0.4 0.033 11.6 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Effector_1 PF04518.7 EEQ33611.1 - 0.05 12.5 1.6 0.061 12.3 1.1 1.3 1 0 0 1 1 1 0 Effector from type III secretion system ApoLp-III PF07464.6 EEQ33611.1 - 0.21 11.5 6.0 1.3 9.0 3.0 2.1 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Exonuc_VII_L PF02601.10 EEQ33611.1 - 0.37 9.9 7.6 0.5 9.5 5.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Synaptobrevin PF00957.16 EEQ33611.1 - 0.69 9.5 0.0 0.69 9.5 0.0 2.5 3 0 0 3 3 3 0 Synaptobrevin zf-C4H2 PF10146.4 EEQ33611.1 - 0.76 9.7 6.6 0.21 11.5 1.8 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein Histone_HNS PF00816.16 EEQ33611.1 - 0.94 10.0 6.3 0.11 12.9 1.2 1.7 2 0 0 2 2 2 0 H-NS histone family TBCA PF02970.11 EEQ33611.1 - 3.3 7.8 8.7 1.2 9.2 1.7 2.6 2 1 0 2 2 2 0 Tubulin binding cofactor A DUF349 PF03993.7 EEQ33611.1 - 3.4 7.9 8.2 18 5.5 1.8 2.9 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) FUSC PF04632.7 EEQ33611.1 - 4.3 5.6 12.4 9.4 4.5 8.6 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF501 PF04417.7 EEQ33611.1 - 4.5 7.1 8.3 4 7.2 1.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF501) DUF1542 PF07564.6 EEQ33611.1 - 4.5 7.3 7.5 1.9 8.5 2.2 2.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1542) DUF2407_C PF13373.1 EEQ33612.1 - 6.3e-42 142.8 0.0 9.4e-42 142.2 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EEQ33612.1 - 7.4e-32 109.4 0.0 1.2e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EEQ33612.1 - 0.00038 19.7 0.0 0.00075 18.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EEQ33612.1 - 0.018 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Bac_chlorC PF02043.12 EEQ33612.1 - 0.39 10.5 2.1 0.82 9.5 1.5 1.4 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein Zn_clus PF00172.13 EEQ33613.1 - 5.3e-08 32.6 7.5 1.1e-07 31.6 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEQ33613.1 - 8.3e-06 24.6 0.0 1.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EEQ33614.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Fe-S_biosyn PF01521.15 EEQ33615.1 - 3.8e-20 71.9 0.0 7.8e-20 70.8 0.0 1.5 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis Pro-kuma_activ PF09286.6 EEQ33615.1 - 0.029 14.3 0.0 0.17 11.9 0.0 2.1 2 1 1 3 3 3 0 Pro-kumamolisin, activation domain 2OG-Fe_Oxy_2 PF10014.4 EEQ33616.1 - 2.3e-47 160.9 0.2 2.7e-47 160.6 0.2 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase MFS_1 PF07690.11 EEQ33617.1 - 9.8e-09 34.3 7.4 1.5e-08 33.7 4.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1741 PF08427.5 EEQ33618.1 - 1.9e-81 272.9 1.3 4.1e-81 271.9 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) DUF2435 PF10363.4 EEQ33618.1 - 0.035 14.0 0.1 14 5.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) MRG PF05712.8 EEQ33619.1 - 5e-42 143.0 1.3 2.9e-35 120.9 0.1 2.2 1 1 1 2 2 2 2 MRG Tudor-knot PF11717.3 EEQ33619.1 - 3.6e-07 29.7 2.3 3.6e-07 29.7 1.6 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.5 EEQ33620.1 - 3.8e-28 96.9 1.9 6.3e-28 96.2 1.3 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein DUF972 PF06156.8 EEQ33620.1 - 0.023 15.0 2.7 0.91 9.9 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 EEQ33620.1 - 0.029 14.1 3.3 0.037 13.8 2.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Med4 PF10018.4 EEQ33620.1 - 0.033 13.5 1.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 D-ser_dehydrat PF14031.1 EEQ33620.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine dehydratase domain IncA PF04156.9 EEQ33620.1 - 0.25 10.8 2.0 1.7 8.1 1.4 2.0 1 1 0 1 1 1 0 IncA protein Vps53_N PF04100.7 EEQ33620.1 - 0.35 9.5 3.7 1 8.0 0.5 2.0 1 1 1 2 2 2 0 Vps53-like, N-terminal DUF3340 PF11818.3 EEQ33620.1 - 0.46 10.4 3.7 0.63 10.0 2.6 1.3 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Ctf8 PF09696.5 EEQ33622.1 - 8.5e-38 128.8 0.1 1.1e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Glyoxalase PF00903.20 EEQ33623.1 - 2e-18 66.5 0.1 9.1e-17 61.2 0.0 2.5 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EEQ33623.1 - 7.8e-10 38.7 0.0 2e-05 24.5 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEQ33623.1 - 5.5e-08 33.3 0.0 0.0011 19.5 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EEQ33623.1 - 1.1e-05 25.4 0.0 0.17 11.7 0.0 3.2 2 2 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EEQ33623.1 - 0.001 18.9 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal HTH_11 PF08279.7 EEQ33623.1 - 0.14 11.8 0.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 HTH domain DUF3813 PF12758.2 EEQ33623.1 - 0.16 12.1 0.3 0.4 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) RabGAP-TBC PF00566.13 EEQ33624.1 - 1.6e-50 171.5 0.3 1.6e-50 171.5 0.2 3.0 2 2 1 3 3 3 1 Rab-GTPase-TBC domain Tropomyosin_1 PF12718.2 EEQ33624.1 - 0.73 9.6 34.5 0.14 12.0 7.2 3.3 3 0 0 3 3 3 0 Tropomyosin like PPTA PF01239.17 EEQ33625.1 - 1e-34 116.3 10.0 1.7e-08 33.4 0.5 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF2605 PF10792.4 EEQ33625.1 - 0.016 14.8 0.8 0.84 9.3 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) HalX PF08663.5 EEQ33625.1 - 0.037 13.9 3.8 0.042 13.8 0.4 2.4 2 0 0 2 2 2 0 HalX domain WD40 PF00400.27 EEQ33626.1 - 2.8e-14 52.3 0.8 5.9e-08 32.2 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 EEQ33626.1 - 0.2 11.3 0.2 28 4.3 0.0 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A APH PF01636.18 EEQ33627.1 - 3.2e-16 59.8 0.0 6.3e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Utp12 PF04003.7 EEQ33628.1 - 1.3e-23 82.9 0.3 6.8e-23 80.6 0.2 2.1 2 0 0 2 2 2 1 Dip2/Utp12 Family Bromodomain PF00439.20 EEQ33629.1 - 1.3e-20 73.0 1.4 2e-20 72.4 0.2 2.0 2 0 0 2 2 2 1 Bromodomain DUF812 PF05667.6 EEQ33629.1 - 0.0036 15.9 2.5 0.0068 14.9 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3573 PF12097.3 EEQ33629.1 - 0.049 12.2 1.9 0.096 11.2 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) zf-CSL PF05207.8 EEQ33630.1 - 5.8e-24 83.3 0.3 7.2e-24 83.0 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Frataxin_Cyay PF01491.11 EEQ33631.1 - 3.3e-32 110.5 0.0 4.6e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain AKAP7_NLS PF10469.4 EEQ33632.1 - 7e-15 55.2 0.0 1.6e-14 54.1 0.0 1.7 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.8 EEQ33633.1 - 1.4e-170 568.1 2.9 1.4e-170 568.1 2.0 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 Ribosomal_L30 PF00327.15 EEQ33634.1 - 5.6e-14 51.4 0.2 7.8e-14 51.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e OstA_2 PF13100.1 EEQ33634.1 - 0.13 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 OstA-like protein Pyridoxal_deC PF00282.14 EEQ33635.1 - 6.7e-17 60.9 0.0 1.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EEQ33635.1 - 3.3e-06 26.0 0.0 1.6e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ33635.1 - 0.00057 19.0 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EEQ33636.1 - 1.7e-91 306.8 0.0 2e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-H2C2_2 PF13465.1 EEQ33638.1 - 5.4e-20 70.6 24.3 2.8e-07 30.4 0.9 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ33638.1 - 1.6e-19 68.9 27.3 4e-05 23.7 1.2 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ33638.1 - 3.1e-12 45.8 29.9 0.00046 20.3 3.1 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ33638.1 - 0.00026 21.0 13.7 0.18 11.9 0.1 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ33638.1 - 0.022 14.6 17.5 1.1 9.3 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger XPA_N PF01286.13 EEQ33638.1 - 0.11 12.1 0.4 0.11 12.1 0.3 2.9 4 0 0 4 4 4 0 XPA protein N-terminal C1_1 PF00130.17 EEQ33638.1 - 0.49 10.1 6.1 0.49 10.1 0.7 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met PF12874.2 EEQ33638.1 - 0.63 10.3 20.3 0.41 10.9 0.2 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Yippee-Mis18 PF03226.9 EEQ33638.1 - 0.86 9.6 2.8 9.3 6.3 0.2 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn-ribbon_8 PF09723.5 EEQ33638.1 - 1.1 9.2 10.3 31 4.6 0.1 3.8 3 1 0 3 3 3 0 Zinc ribbon domain C1_4 PF07975.7 EEQ33638.1 - 3.6 7.6 5.4 6.9 6.7 0.1 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain BTB PF00651.26 EEQ33639.1 - 0.067 13.1 0.0 0.2 11.6 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain UPF0547 PF10571.4 EEQ33639.1 - 0.22 11.2 4.0 0.53 10.0 2.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-C2H2 PF00096.21 EEQ33639.1 - 0.23 11.8 6.8 4.7 7.7 0.0 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Methyltransf_23 PF13489.1 EEQ33640.1 - 7.4e-22 77.7 0.0 3.5e-21 75.6 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ33640.1 - 3.3e-14 53.1 0.0 2.8e-13 50.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ33640.1 - 5.3e-13 49.2 0.0 1.2e-12 48.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ33640.1 - 1.6e-10 41.5 0.0 2.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ33640.1 - 4.9e-10 39.1 0.0 4.7e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ33640.1 - 2.4e-07 31.0 0.0 4.6e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ33640.1 - 5.4e-07 29.6 0.0 9.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EEQ33640.1 - 0.0052 16.1 0.0 0.25 10.7 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) Prp18 PF02840.10 EEQ33640.1 - 0.073 12.8 0.3 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Prp18 domain NNMT_PNMT_TEMT PF01234.12 EEQ33640.1 - 0.11 11.4 0.1 0.86 8.5 0.0 2.2 3 0 0 3 3 3 0 NNMT/PNMT/TEMT family Pkinase PF00069.20 EEQ33642.1 - 3.5e-07 29.6 0.0 4.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EEQ33642.1 - 1.7e-05 23.9 0.1 2.5e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ33642.1 - 9.9e-05 22.1 0.2 0.00084 19.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ33642.1 - 0.02 14.4 0.1 0.02 14.4 0.1 1.7 3 0 0 3 3 3 0 Choline/ethanolamine kinase EcKinase PF02958.15 EEQ33642.1 - 0.024 13.7 0.1 0.043 12.9 0.1 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 EEQ33642.1 - 0.039 13.3 0.1 0.063 12.6 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 EEQ33642.1 - 0.064 12.3 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase E1-E2_ATPase PF00122.15 EEQ33643.1 - 2.9e-53 180.2 0.2 5.8e-53 179.2 0.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ33643.1 - 8.7e-33 113.3 3.9 8.7e-33 113.3 2.7 2.1 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EEQ33643.1 - 4e-24 84.3 0.0 8.8e-24 83.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEQ33643.1 - 5.2e-14 51.4 0.2 1.2e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.21 EEQ33643.1 - 1.3e-10 42.0 0.0 2.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ33643.1 - 0.00075 19.1 0.8 0.0012 18.4 0.5 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ33643.1 - 0.017 15.2 0.0 0.052 13.7 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase BRAP2 PF07576.7 EEQ33644.1 - 3.6e-24 84.4 0.0 7.4e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EEQ33644.1 - 7.9e-20 70.7 4.0 2.7e-19 69.0 2.8 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EEQ33644.1 - 2.1e-09 37.0 10.0 2.1e-09 37.0 6.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EEQ33644.1 - 7.8e-05 22.3 7.2 7.8e-05 22.3 5.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEQ33644.1 - 0.00052 19.6 7.7 0.00052 19.6 5.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ33644.1 - 0.00084 18.9 5.7 0.00084 18.9 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ33644.1 - 0.0012 18.8 9.0 0.0012 18.8 6.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ33644.1 - 0.0024 17.9 5.2 0.0024 17.9 3.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EEQ33644.1 - 0.0026 17.4 3.9 0.0073 15.9 1.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger FTA4 PF13093.1 EEQ33644.1 - 0.043 13.2 2.6 0.081 12.3 1.8 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 zf-Apc11 PF12861.2 EEQ33644.1 - 0.052 13.3 8.1 0.045 13.5 4.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ApoO PF09769.4 EEQ33644.1 - 0.08 12.6 0.1 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein O TPR_MLP1_2 PF07926.7 EEQ33644.1 - 0.18 11.5 14.0 0.36 10.5 9.7 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 EEQ33644.1 - 0.23 11.7 2.9 0.27 11.5 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) zf-RING_6 PF14835.1 EEQ33644.1 - 0.33 10.7 12.4 0.17 11.7 4.7 2.5 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Exonuc_VII_L PF02601.10 EEQ33644.1 - 0.5 9.5 6.7 0.96 8.5 4.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_RING PF05883.6 EEQ33644.1 - 0.9 9.3 5.2 3.5 7.4 3.5 2.0 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain APG6 PF04111.7 EEQ33644.1 - 0.95 8.4 9.6 6.1 5.7 7.6 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3450 PF11932.3 EEQ33644.1 - 0.98 8.6 10.9 1.7 7.8 7.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Prok-RING_4 PF14447.1 EEQ33644.1 - 1.5 8.4 9.0 7.6 6.1 2.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DivIC PF04977.10 EEQ33644.1 - 6.4 6.3 7.8 3 7.3 0.3 2.5 1 1 0 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.14 EEQ33644.1 - 7.5 4.2 5.7 11 3.6 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ubiquitin PF00240.18 EEQ33645.1 - 7.2e-136 441.7 24.5 1.1e-33 114.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EEQ33645.1 - 1.3e-77 255.4 22.7 5.6e-19 67.6 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEQ33645.1 - 5.3e-24 84.2 11.9 0.00016 21.8 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEQ33645.1 - 3.2e-21 75.7 1.5 0.0012 18.5 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing DUF2407 PF10302.4 EEQ33645.1 - 5.6e-14 52.0 2.5 0.11 12.7 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EEQ33645.1 - 8.9e-14 51.3 3.5 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EEQ33645.1 - 1.3e-10 41.1 0.0 1.5 8.8 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 EEQ33645.1 - 2.1e-06 27.0 0.7 1.4 8.0 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 EEQ33645.1 - 4.6e-06 26.2 5.5 6.8 6.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain IGR PF09597.5 EEQ33645.1 - 1.4e-05 24.8 0.3 24 4.8 0.0 4.3 4 0 0 4 4 4 0 IGR protein motif Big_3_3 PF13750.1 EEQ33645.1 - 2.4e-05 23.7 0.1 19 4.6 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) TUG-UBL1 PF11470.3 EEQ33645.1 - 3e-05 23.8 6.9 7.8 6.4 0.1 4.2 4 0 0 4 4 4 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 EEQ33645.1 - 0.0024 18.1 0.7 1.1e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 ACT domain USP7_C2 PF14533.1 EEQ33645.1 - 0.0032 16.9 5.1 5.6 6.3 0.3 3.8 1 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal Plexin_cytopl PF08337.7 EEQ33645.1 - 0.0039 15.5 14.0 3.6 5.7 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 EEQ33645.1 - 0.0096 16.0 5.7 56 3.9 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Sortase PF04203.8 EEQ33645.1 - 0.021 14.4 2.5 37 3.9 0.0 3.9 2 1 2 4 4 4 0 Sortase family Tash_PEST PF07708.6 EEQ33645.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif CTDII PF01556.13 EEQ33645.1 - 0.038 13.8 16.6 6.6 6.7 0.3 4.5 1 1 3 4 4 4 0 DnaJ C terminal domain GABP-alpha PF11620.3 EEQ33645.1 - 0.051 13.5 7.8 47 4.0 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain DUF3781 PF12636.2 EEQ33645.1 - 0.97 9.4 7.8 1.2e+02 2.7 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 EEQ33645.1 - 1.1 9.4 14.8 57 3.8 0.2 5.9 4 4 0 4 4 4 0 FERM N-terminal domain Zn_clus PF00172.13 EEQ33646.1 - 0.007 16.2 7.8 0.007 16.2 5.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.16 EEQ33647.1 - 3e-30 103.4 39.8 1e-12 47.3 1.2 6.4 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEQ33647.1 - 1.6e-27 96.1 1.0 1.8e-16 60.5 0.1 4.2 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEQ33647.1 - 0.0001 22.2 0.3 0.47 10.4 0.0 3.6 3 2 0 3 3 3 2 Prenyltransferase-like PY_rept_46 PF09689.5 EEQ33647.1 - 0.058 13.7 2.1 0.096 13.0 1.4 1.3 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) dsrm PF00035.20 EEQ33648.1 - 4.8e-05 23.8 0.0 8.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EEQ33648.1 - 0.0016 18.6 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 DUF1183 PF06682.7 EEQ33649.1 - 0.019 14.5 0.3 0.028 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4448 PF14610.1 EEQ33650.1 - 2.2e-42 144.7 0.0 5.4e-42 143.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Herpes_U47 PF05467.6 EEQ33650.1 - 0.00043 18.2 2.5 0.0005 18.0 1.7 1.1 1 0 0 1 1 1 1 Herpesvirus glycoprotein U47 Hpt PF01627.18 EEQ33651.1 - 5.5e-13 48.7 0.0 1.1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Hpt domain HMGL-like PF00682.14 EEQ33652.1 - 7.9e-52 176.2 0.9 2.7e-44 151.5 0.4 2.4 1 1 1 2 2 2 2 HMGL-like PTH2 PF01981.11 EEQ33654.1 - 9.4e-43 144.5 0.0 1.2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 S-antigen PF05756.6 EEQ33654.1 - 0.024 14.5 0.2 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 S-antigen protein SART-1 PF03343.8 EEQ33655.1 - 1.7e-166 555.1 58.7 1.7e-166 555.1 40.7 1.6 2 0 0 2 2 2 1 SART-1 family WD40 PF00400.27 EEQ33656.1 - 1.7e-19 68.8 6.8 5.4e-06 26.0 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat BSD PF03909.12 EEQ33657.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 BSD domain Occludin_ELL PF07303.8 EEQ33657.1 - 0.14 12.9 3.4 0.071 13.8 0.5 1.9 2 0 0 2 2 2 0 Occludin homology domain DUF155 PF02582.9 EEQ33661.1 - 6.2e-58 195.5 0.0 1.2e-57 194.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Aldedh PF00171.17 EEQ33662.1 - 1.4e-147 491.8 0.2 1.5e-147 491.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TarH PF02203.10 EEQ33662.1 - 0.059 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Sel1 PF08238.7 EEQ33663.1 - 1.9e-34 117.2 56.3 1.2e-05 25.7 0.4 13.0 13 1 2 15 15 15 8 Sel1 repeat TPR_14 PF13428.1 EEQ33663.1 - 0.00086 19.7 3.5 20 6.1 0.0 5.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Nucleo_P87 PF07267.6 EEQ33663.1 - 0.092 11.4 6.9 0.14 10.7 4.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mei5 PF10376.4 EEQ33663.1 - 1.5 8.3 11.0 4.5 6.7 3.7 2.4 2 0 0 2 2 2 0 Double-strand recombination repair protein Dus PF01207.12 EEQ33664.1 - 3.7e-41 140.9 0.0 7.6e-29 100.5 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EEQ33664.1 - 1.7e-05 24.3 2.9 0.043 13.5 0.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_5 PF13854.1 EEQ33665.1 - 8.5e-24 83.0 0.3 2.8e-06 27.1 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 EEQ33665.1 - 2.5e-23 81.5 4.3 5.9e-08 32.3 0.0 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EEQ33665.1 - 6.1e-21 73.3 2.4 5e-07 29.2 0.1 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EEQ33665.1 - 7.1e-21 73.4 1.1 2.8e-05 24.0 0.0 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 EEQ33665.1 - 4.8e-19 67.6 0.4 6.2e-05 22.4 0.1 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 EEQ33665.1 - 1.1e-18 66.8 7.7 1.9e-07 31.0 0.0 5.4 6 0 0 6 6 6 3 Galactose oxidase, central domain BTB PF00651.26 EEQ33665.1 - 1.8e-08 34.3 0.0 3.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 EEQ33666.1 - 2.7e-22 77.7 16.8 2.2e-06 27.3 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EEQ33666.1 - 0.00014 21.6 0.3 0.011 15.5 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A TFIIA PF03153.8 EEQ33667.1 - 4.6e-82 276.8 12.6 7.1e-82 276.2 8.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Toxin_39 PF15500.1 EEQ33667.1 - 0.044 13.9 0.2 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Putative RNase-like toxin Stm1_N PF09598.5 EEQ33668.1 - 8 7.2 15.6 0.058 14.0 1.8 3.4 3 0 0 3 3 3 0 Stm1 Bap31 PF05529.7 EEQ33669.1 - 4.9e-65 218.5 0.3 5.7e-65 218.3 0.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EEQ33669.1 - 0.0054 16.5 1.3 0.01 15.6 0.9 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 EEQ33669.1 - 0.0086 15.5 2.9 0.012 15.0 2.0 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 TMF_TATA_bd PF12325.3 EEQ33669.1 - 0.0088 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4349 PF14257.1 EEQ33669.1 - 0.031 13.5 0.2 0.067 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DivIC PF04977.10 EEQ33669.1 - 0.035 13.5 2.1 0.087 12.3 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.6 EEQ33669.1 - 0.049 12.2 0.6 0.079 11.6 0.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.6 EEQ33669.1 - 0.093 12.4 0.9 0.14 11.8 0.6 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2404 PF10296.4 EEQ33670.1 - 7e-05 22.8 0.0 0.0034 17.4 0.0 2.3 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) NACHT PF05729.7 EEQ33674.1 - 5e-08 32.7 2.0 5e-08 32.7 1.4 2.2 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EEQ33674.1 - 3.7e-06 27.0 1.9 0.0041 17.1 0.1 3.0 1 1 1 2 2 2 2 AAA ATPase domain AAA PF00004.24 EEQ33674.1 - 0.0018 18.4 0.0 0.0065 16.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 EEQ33674.1 - 0.0018 17.3 3.0 0.0046 15.9 0.4 2.3 1 1 0 2 2 2 1 KAP family P-loop domain APS_kinase PF01583.15 EEQ33674.1 - 0.0031 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 EEQ33674.1 - 0.0033 17.7 0.0 0.0094 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ33674.1 - 0.0046 17.7 0.0 0.016 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ33674.1 - 0.005 16.9 0.6 0.051 13.7 0.2 2.8 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEQ33674.1 - 0.0075 16.4 0.1 0.28 11.3 0.0 3.0 3 0 0 3 3 3 1 RNA helicase NB-ARC PF00931.17 EEQ33674.1 - 0.044 12.6 0.1 0.36 9.6 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.1 EEQ33674.1 - 0.051 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EEQ33674.1 - 0.052 12.9 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase MobB PF03205.9 EEQ33674.1 - 0.071 12.8 0.1 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EEQ33674.1 - 0.081 12.4 0.2 0.18 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEQ33674.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PAC2 PF09754.4 EEQ33674.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 PAC2 family Pkinase PF00069.20 EEQ33675.1 - 8.5e-63 211.9 0.0 1.5e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33675.1 - 9.6e-35 119.8 0.0 9.6e-30 103.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ33675.1 - 5.5e-05 22.2 0.0 0.036 13.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EEQ33675.1 - 0.0012 18.2 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EEQ33675.1 - 0.0027 17.4 0.0 0.0083 15.8 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ33675.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Senescence PF06911.7 EEQ33676.1 - 1e-48 165.4 0.4 1.4e-48 164.9 0.3 1.2 1 0 0 1 1 1 1 Senescence-associated protein Stanniocalcin PF03298.8 EEQ33677.1 - 0.0015 17.6 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Stanniocalcin family Acyl-CoA_dh_1 PF00441.19 EEQ33678.1 - 3.4e-39 134.3 6.7 5.5e-39 133.6 4.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ33678.1 - 4.5e-30 104.5 2.6 5.1e-30 104.3 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ33678.1 - 5.5e-17 61.0 0.0 1.1e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEQ33678.1 - 2.5e-13 50.4 3.2 2.5e-13 50.4 2.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EEQ33678.1 - 0.026 13.9 0.1 0.12 11.7 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF3662 PF12401.3 EEQ33678.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) AgrD PF05931.6 EEQ33678.1 - 0.13 11.8 0.1 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Staphylococcal AgrD protein MFS_1 PF07690.11 EEQ33679.1 - 5e-27 94.5 36.6 5.6e-22 77.9 7.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEQ33679.1 - 0.00028 19.4 0.8 0.00028 19.4 0.5 3.3 3 1 1 4 4 4 3 MFS/sugar transport protein GWT1 PF06423.7 EEQ33681.1 - 2.9e-41 140.7 3.0 2.9e-41 140.7 2.1 2.0 2 0 0 2 2 2 1 GWT1 Amidase PF01425.16 EEQ33682.1 - 1.6e-82 277.7 0.1 2e-82 277.3 0.1 1.1 1 0 0 1 1 1 1 Amidase Sec63 PF02889.11 EEQ33683.1 - 3.4e-43 148.0 0.0 2.7e-42 145.1 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EEQ33683.1 - 2.2e-17 62.5 0.6 5e-17 61.3 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.19 EEQ33684.1 - 9.5e-47 159.2 0.0 1.4e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EEQ33684.1 - 7.6e-25 86.8 0.0 1.6e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3761 PF12587.3 EEQ33684.1 - 0.035 14.1 0.1 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) SPRY PF00622.23 EEQ33686.1 - 4.7e-17 62.2 0.0 7.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain DUF3611 PF12263.3 EEQ33686.1 - 0.046 13.1 0.1 0.088 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) BAF1_ABF1 PF04684.8 EEQ33686.1 - 6 5.5 10.2 9.5 4.9 7.1 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PDEase_II PF02112.10 EEQ33687.1 - 1.6e-35 122.6 0.0 4.6e-18 65.2 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EEQ33687.1 - 0.0038 16.7 0.0 0.0067 15.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEQ33687.1 - 0.025 14.2 3.1 0.076 12.6 2.1 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF605 PF04652.11 EEQ33687.1 - 0.34 10.2 17.1 0.48 9.7 11.9 1.2 1 0 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 EEQ33688.1 - 1.6e-15 56.6 0.1 2.4e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EEQ33689.1 - 6.6e-16 58.6 0.1 1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ33689.1 - 2.3e-08 33.9 0.1 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.13 EEQ33690.1 - 5.6e-09 35.7 11.7 1.4e-08 34.4 8.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DNL PF05180.7 EEQ33690.1 - 6.1 6.6 8.4 13 5.5 0.0 3.0 3 0 0 3 3 3 0 DNL zinc finger ALO PF04030.9 EEQ33692.1 - 3.6e-91 305.3 0.1 5.3e-91 304.7 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EEQ33692.1 - 8.5e-32 109.5 0.1 1.4e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4045 PF13254.1 EEQ33694.1 - 3.1e-113 379.2 39.4 5.3e-70 236.8 19.7 6.0 3 3 2 5 5 5 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EEQ33694.1 - 1.8e-13 49.9 0.0 0.003 17.2 0.0 3.9 3 0 0 3 3 3 3 Gelsolin repeat Arf PF00025.16 EEQ33695.1 - 2.5e-51 173.3 1.5 1.1e-48 164.8 1.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EEQ33695.1 - 4.4e-08 32.2 1.6 0.0042 15.8 0.0 2.7 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EEQ33695.1 - 0.00022 21.1 0.1 0.0065 16.4 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ33695.1 - 0.00035 20.0 0.1 0.03 13.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEQ33695.1 - 0.00049 19.3 0.0 0.23 10.5 0.0 2.1 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region Ras PF00071.17 EEQ33695.1 - 0.0023 17.3 0.0 0.018 14.4 0.0 1.8 1 1 1 2 2 2 1 Ras family HCV_NS1 PF01560.12 EEQ33695.1 - 0.015 13.7 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 SRPRB PF09439.5 EEQ33695.1 - 0.053 12.7 0.0 1.6 7.9 0.0 2.1 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EEQ33695.1 - 0.079 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EEQ33695.1 - 0.091 13.2 0.1 1.3 9.5 0.0 2.0 1 1 1 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EEQ33695.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 1 1 2 2 2 0 Dynamin family Acetyltransf_3 PF13302.1 EEQ33696.1 - 0.0011 19.1 0.0 0.0029 17.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEQ33696.1 - 0.05 13.5 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.24 EEQ33697.1 - 3.1e-43 147.1 0.1 9.4e-43 145.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ33697.1 - 9.9e-26 89.4 0.0 3.6e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EEQ33697.1 - 3.4e-05 22.4 0.9 0.00018 20.0 0.1 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) HMGL-like PF00682.14 EEQ33698.1 - 2.9e-68 230.0 0.0 6.1e-68 229.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EEQ33698.1 - 6.4e-21 74.5 0.0 1.2e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain PPK2 PF03976.9 EEQ33698.1 - 0.025 13.8 0.2 0.058 12.6 0.2 1.5 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) AMP-binding PF00501.23 EEQ33699.1 - 1.5e-57 194.8 1.0 4e-24 84.7 0.0 5.0 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 EEQ33699.1 - 1e-09 38.9 0.1 3.7e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.7 EEQ33699.1 - 0.0014 18.4 0.5 0.0029 17.3 0.3 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Carb_anhydrase PF00194.16 EEQ33700.1 - 3.1e-24 85.3 0.0 1.4e-23 83.1 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RNR_inhib PF08591.5 EEQ33701.1 - 1.8e-17 64.0 0.6 1.8e-17 64.0 0.4 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor CPSase_sm_chain PF00988.17 EEQ33701.1 - 0.048 13.1 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain SDA1 PF05285.7 EEQ33702.1 - 6e-91 305.0 34.1 6e-91 305.0 23.6 2.2 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 EEQ33702.1 - 2.4e-22 78.9 0.1 5.9e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 NUC130/3NT domain Ribosomal_S7 PF00177.16 EEQ33703.1 - 1.2e-40 138.4 1.2 1.5e-40 138.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Methyltransf_23 PF13489.1 EEQ33704.1 - 3.4e-16 59.3 0.0 5.9e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ33704.1 - 3.1e-08 33.3 0.0 2e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ33704.1 - 1.5e-07 31.7 0.0 1.8e-06 28.3 0.0 2.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ33704.1 - 1e-06 29.1 0.0 2.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ33704.1 - 1.1e-06 29.2 0.0 1.5e-05 25.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ33704.1 - 1.2e-05 25.5 0.0 3.6e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ33704.1 - 0.0005 19.4 0.0 0.00082 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EEQ33704.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EEQ33704.1 - 0.016 14.3 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EEQ33704.1 - 0.017 14.1 0.0 0.06 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 EEQ33704.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EEQ33704.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ33704.1 - 0.15 11.1 0.0 1.2 8.2 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.17 EEQ33705.1 - 2.9e-61 207.4 0.0 3.5e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.23 EEQ33706.1 - 2.1e-09 37.0 1.1 3.6e-09 36.3 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EEQ33706.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain 4HBT_3 PF13622.1 EEQ33707.1 - 1.4e-44 152.7 1.1 1.9e-44 152.3 0.8 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EEQ33707.1 - 2.4e-24 85.4 0.0 1e-10 41.3 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase DUF3445 PF11927.3 EEQ33708.1 - 1.7e-59 201.2 0.0 3.1e-59 200.3 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3445) HSP70 PF00012.15 EEQ33710.1 - 1.5e-10 39.6 0.1 4.3e-09 34.8 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EEQ33710.1 - 0.0051 16.4 0.2 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EEQ33710.1 - 0.11 11.0 0.0 0.31 9.6 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein N2227 PF07942.7 EEQ33711.1 - 1.6e-57 194.5 0.0 2.5e-39 134.8 0.0 2.7 1 1 1 2 2 2 2 N2227-like protein Fungal_trans PF04082.13 EEQ33714.1 - 3.1e-24 85.2 0.2 5.4e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ33714.1 - 0.0013 18.6 3.4 0.0038 17.0 2.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.15 EEQ33715.1 - 1e-22 79.8 4.9 1.4e-22 79.4 3.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF2240 PF09999.4 EEQ33715.1 - 0.046 13.1 0.2 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Spore_III_AF PF09581.5 EEQ33715.1 - 0.074 12.9 3.6 0.099 12.5 2.5 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Prefoldin PF02996.12 EEQ33715.1 - 0.57 9.8 5.9 0.33 10.6 1.5 2.0 1 1 1 2 2 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.4 EEQ33715.1 - 1.5 8.6 17.1 0.39 10.5 1.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EEQ33715.1 - 2.2 7.4 10.8 7.6 5.6 3.5 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 EEQ33715.1 - 2.3 8.2 11.6 1.4 8.9 0.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HAUS6_N PF14661.1 EEQ33715.1 - 5.2 6.3 7.4 9.3 5.5 2.7 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF848 PF05852.6 EEQ33715.1 - 5.4 6.8 8.8 13 5.5 3.2 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TBPIP PF07106.8 EEQ33715.1 - 5.7 6.4 8.5 30 4.1 5.9 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EEQ33715.1 - 5.7 5.4 10.4 1.5 7.4 0.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein ATG27 PF09451.5 EEQ33716.1 - 1.4e-60 204.8 5.0 2.5e-60 204.0 3.5 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EEQ33716.1 - 0.00018 21.2 0.0 0.03 14.0 0.0 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF1242 PF06842.7 EEQ33716.1 - 0.12 11.9 4.2 0.24 10.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) AAA_2 PF07724.9 EEQ33720.1 - 1.6e-45 155.0 0.0 1.9e-43 148.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EEQ33720.1 - 4.5e-27 94.8 0.0 2.7e-15 56.7 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EEQ33720.1 - 6.1e-22 77.3 1.1 1.5e-21 76.0 0.0 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EEQ33720.1 - 2.4e-16 60.2 4.0 1.1e-05 25.5 0.0 5.3 3 2 1 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 EEQ33720.1 - 2.1e-15 56.6 0.4 2.1e-08 33.9 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ33720.1 - 7.5e-14 52.0 0.3 9.9e-05 22.4 0.0 3.9 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EEQ33720.1 - 4.4e-09 36.0 0.0 5.4e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EEQ33720.1 - 4.1e-08 34.0 2.5 0.0071 17.1 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EEQ33720.1 - 9.2e-08 32.4 0.6 0.01 16.1 0.0 4.1 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 EEQ33720.1 - 2.2e-07 30.4 0.0 0.031 13.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EEQ33720.1 - 3e-07 30.3 0.0 0.027 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EEQ33720.1 - 3.1e-07 30.3 1.9 0.027 14.1 0.0 4.9 6 0 0 6 6 4 2 Archaeal ATPase AAA_19 PF13245.1 EEQ33720.1 - 3.2e-07 29.9 0.0 0.013 15.2 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 EEQ33720.1 - 1.1e-05 25.4 0.3 0.5 10.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EEQ33720.1 - 1.7e-05 24.7 0.0 0.18 11.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EEQ33720.1 - 2.1e-05 24.2 0.0 0.094 12.4 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 EEQ33720.1 - 2.8e-05 23.3 0.0 0.13 11.3 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEQ33720.1 - 3.5e-05 23.9 0.0 0.48 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Clp_N PF02861.15 EEQ33720.1 - 4.5e-05 23.2 4.1 0.027 14.3 0.0 4.4 5 0 0 5 5 4 1 Clp amino terminal domain AAA_3 PF07726.6 EEQ33720.1 - 4.7e-05 23.0 0.0 0.45 10.1 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEQ33720.1 - 0.00014 20.9 0.7 0.12 11.4 0.0 3.5 4 1 0 4 4 4 1 Zeta toxin AAA_25 PF13481.1 EEQ33720.1 - 0.00019 20.9 0.0 1.2 8.5 0.0 3.3 2 1 1 3 3 3 2 AAA domain ABC_tran PF00005.22 EEQ33720.1 - 0.00019 21.7 0.2 0.76 10.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter T2SE PF00437.15 EEQ33720.1 - 0.00045 19.2 0.0 0.025 13.4 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 EEQ33720.1 - 0.00057 19.4 0.6 0.23 10.8 0.0 3.8 3 2 1 4 4 4 1 AAA-like domain NTPase_1 PF03266.10 EEQ33720.1 - 0.00084 19.0 0.1 0.095 12.4 0.0 3.4 3 0 0 3 3 3 1 NTPase ResIII PF04851.10 EEQ33720.1 - 0.00094 19.0 0.0 0.33 10.7 0.0 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DUF258 PF03193.11 EEQ33720.1 - 0.00099 18.3 0.0 0.41 9.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EEQ33720.1 - 0.0013 18.3 0.0 1.9 7.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EEQ33720.1 - 0.0014 18.5 0.1 0.018 14.9 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EEQ33720.1 - 0.0017 17.8 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Torsin PF06309.6 EEQ33720.1 - 0.0021 17.9 0.0 0.0087 15.9 0.0 1.9 2 0 0 2 2 2 1 Torsin NACHT PF05729.7 EEQ33720.1 - 0.003 17.2 0.0 0.25 11.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.17 EEQ33720.1 - 0.0073 15.7 0.0 1.3 8.4 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EEQ33720.1 - 0.0081 15.7 0.0 6.5 6.2 0.0 3.4 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.1 EEQ33720.1 - 0.011 15.7 0.0 1.9 8.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EEQ33720.1 - 0.014 14.3 1.7 0.14 11.1 0.2 2.9 1 1 2 3 3 3 0 KAP family P-loop domain UPF0079 PF02367.12 EEQ33720.1 - 0.045 13.3 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 EEQ33720.1 - 0.093 12.2 0.1 17 4.8 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 EEQ33720.1 - 1.5 9.1 0.0 1.5 9.1 0.0 4.1 3 1 0 3 3 2 0 AAA domain SNF2_N PF00176.18 EEQ33721.1 - 1.1e-67 227.9 0.0 1.8e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ33721.1 - 1.9e-11 43.6 0.0 4.3e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ33721.1 - 1.4e-05 25.0 0.0 4.2e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SDF PF00375.13 EEQ33722.1 - 2.3 6.8 0.4 3.4 6.3 0.3 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family EBP PF05241.7 EEQ33723.1 - 2.1e-65 219.4 12.9 2.6e-65 219.1 8.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2347 PF09804.4 EEQ33724.1 - 5.7e-102 340.7 0.0 8e-102 340.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EEQ33724.1 - 2e-52 177.8 0.8 2.9e-52 177.3 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 EEQ33724.1 - 4.6e-07 28.6 0.0 0.004 15.6 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EEQ33724.1 - 9.3e-05 22.1 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DinB_2 PF12867.2 EEQ33725.1 - 0.18 12.1 1.8 0.95 9.8 0.1 2.6 2 0 0 2 2 2 0 DinB superfamily Peptidase_S46 PF10459.4 EEQ33725.1 - 2.2 6.6 9.6 3.6 5.9 6.6 1.3 1 0 0 1 1 1 0 Peptidase S46 V_ATPase_I PF01496.14 EEQ33725.1 - 2.4 5.9 5.2 4.3 5.0 3.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kisspeptin PF15152.1 EEQ33725.1 - 4.7 7.9 9.5 0.62 10.7 1.6 3.2 2 1 0 2 2 2 0 Kisspeptin TPR_MLP1_2 PF07926.7 EEQ33725.1 - 7.3 6.3 20.3 7.5 6.3 11.9 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tubulin_3 PF14881.1 EEQ33726.1 - 9.9e-82 272.7 0.0 1.6e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EEQ33726.1 - 1.4e-41 141.1 0.0 3e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EEQ33726.1 - 1.1e-06 28.6 0.0 0.00056 19.7 0.0 2.5 3 0 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain HSP70 PF00012.15 EEQ33729.1 - 1.8e-62 211.1 4.2 4.4e-58 196.6 0.4 2.5 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EEQ33729.1 - 0.0051 15.4 0.6 0.015 13.8 0.1 2.1 2 1 0 2 2 2 1 MreB/Mbl protein MFS_1 PF07690.11 EEQ33730.1 - 1.1e-26 93.3 57.1 2.1e-25 89.2 39.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily tRNA-synt_1c PF00749.16 EEQ33732.1 - 3.1e-93 311.8 0.0 5.4e-93 311.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEQ33732.1 - 1.9e-30 105.8 0.0 5.8e-30 104.2 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain WD40 PF00400.27 EEQ33734.1 - 4.8e-09 35.7 8.2 0.012 15.4 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat MFS_1 PF07690.11 EEQ33735.1 - 9.2e-49 166.0 50.6 4.1e-47 160.6 35.7 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ33735.1 - 6.7e-19 67.5 24.4 1e-18 66.9 16.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ33735.1 - 2.1e-15 56.2 17.0 2.1e-15 56.2 11.8 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter Spore_YhaL PF14147.1 EEQ33735.1 - 0.00067 19.0 0.1 0.002 17.5 0.0 1.8 1 0 0 1 1 1 1 Sporulation protein YhaL ATP-grasp_4 PF13535.1 EEQ33736.1 - 2.5e-26 92.5 0.0 3.2e-23 82.4 0.0 3.1 3 1 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEQ33736.1 - 3.6e-07 29.7 0.0 4.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EEQ33736.1 - 1.4e-05 25.0 0.0 0.00073 19.4 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEQ33736.1 - 0.00081 18.2 0.0 0.68 8.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GSH-S_ATP PF02955.11 EEQ33736.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.1 EEQ33736.1 - 0.096 11.7 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GDPD PF03009.12 EEQ33737.1 - 2.8e-42 144.9 0.0 1.2e-41 142.9 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EEQ33737.1 - 3.7e-27 94.5 1.0 8.4e-12 45.2 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ33737.1 - 6e-18 64.8 0.4 4.8e-05 23.7 0.1 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EEQ33737.1 - 1.1e-15 56.5 5.9 0.0033 17.1 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EEQ33737.1 - 1.4e-13 50.5 1.2 0.0088 16.2 0.0 5.7 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ33737.1 - 2.5e-12 45.7 0.9 0.0014 18.6 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat SPX PF03105.14 EEQ33737.1 - 0.00016 21.5 6.2 0.0033 17.2 3.6 3.0 2 1 0 2 2 2 1 SPX domain Corona_nucleoca PF00937.13 EEQ33737.1 - 0.011 14.7 1.3 2.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Ank_2 PF12796.2 EEQ33738.1 - 6.4e-32 109.7 0.0 2.6e-13 50.1 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ33738.1 - 1.3e-29 100.4 2.1 3e-07 29.9 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EEQ33738.1 - 1.2e-24 86.1 1.7 4.6e-05 23.8 0.0 6.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ33738.1 - 6.3e-19 66.1 1.4 0.00063 19.7 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EEQ33738.1 - 7.9e-19 67.2 2.0 2e-05 24.6 0.0 5.6 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Fungal_trans PF04082.13 EEQ33739.1 - 9.5e-21 73.8 0.2 3.8e-19 68.5 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Kdo_hydroxy PF11004.3 EEQ33741.1 - 0.029 13.3 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase MFS_1 PF07690.11 EEQ33742.1 - 2.2e-44 151.6 34.1 2.2e-44 151.6 23.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ33742.1 - 5.9e-15 54.8 16.3 1.1e-14 53.8 11.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Folate_carrier PF01770.13 EEQ33742.1 - 0.023 13.2 0.5 0.023 13.2 0.3 2.6 3 1 0 3 3 3 0 Reduced folate carrier Vps55 PF04133.9 EEQ33742.1 - 5.7 6.7 11.7 0.045 13.4 0.5 3.1 3 0 0 3 3 3 0 Vacuolar protein sorting 55 Alpha-amylase PF00128.19 EEQ33744.1 - 9e-30 104.1 0.0 2.9e-29 102.4 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EEQ33744.1 - 5.5e-06 24.4 1.0 0.021 12.5 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Alpha-amylase_C PF02806.13 EEQ33744.1 - 0.0015 18.6 0.0 0.012 15.7 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain 3A PF00803.13 EEQ33744.1 - 0.047 12.7 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 3A/RNA2 movement protein family DEAD PF00270.24 EEQ33745.1 - 8.2e-27 93.7 0.0 2.9e-26 91.9 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ33745.1 - 1.4e-20 72.9 0.1 3.4e-20 71.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ33745.1 - 6.7e-07 29.3 0.3 2.3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribonuc_L-PSP PF01042.16 EEQ33746.1 - 7.8e-38 128.9 0.0 8.8e-38 128.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GFA PF04828.9 EEQ33748.1 - 0.0022 17.9 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme HLH PF00010.21 EEQ33749.1 - 2.3e-08 33.6 0.1 6.8e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HNH_2 PF13391.1 EEQ33750.1 - 1.6e-13 50.2 0.6 5.4e-12 45.3 0.1 2.9 3 0 0 3 3 3 1 HNH endonuclease Maf PF02545.9 EEQ33751.1 - 3.1e-36 124.3 0.1 4.2e-18 65.1 0.0 2.1 1 1 1 2 2 2 2 Maf-like protein CybS PF05328.7 EEQ33752.1 - 2.7e-50 169.4 0.0 3.3e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 CybS Glyco_trans_1_4 PF13692.1 EEQ33752.1 - 0.043 13.9 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 ADH_zinc_N PF00107.21 EEQ33753.1 - 2.1e-23 82.2 0.0 3.1e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ33753.1 - 8.9e-09 36.3 0.0 1.5e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_M16 PF00675.15 EEQ33754.1 - 9.6e-56 187.6 0.0 3.3e-55 185.9 0.1 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEQ33754.1 - 3.1e-41 141.0 0.0 2.9e-40 137.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain MFS_1 PF07690.11 EEQ33755.1 - 6.3e-28 97.4 57.2 4.4e-25 88.1 31.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Nitroreductase PF00881.19 EEQ33756.1 - 1.4e-16 60.7 0.0 1.7e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Epimerase PF01370.16 EEQ33757.1 - 4.9e-20 71.9 0.0 6.3e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ33757.1 - 9.8e-09 34.3 0.0 1.3e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEQ33757.1 - 2.3e-06 27.7 0.0 3.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEQ33757.1 - 1.3e-05 25.2 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EEQ33757.1 - 2.6e-05 23.2 0.0 0.0065 15.4 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EEQ33757.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EEQ33757.1 - 0.002 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Fibrillarin PF01269.12 EEQ33758.1 - 1.7e-107 357.5 0.0 2.1e-107 357.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EEQ33758.1 - 5.9e-06 25.9 0.0 9.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EEQ33758.1 - 0.035 13.6 0.1 0.059 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EEQ33758.1 - 0.036 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3455 PF11937.3 EEQ33759.1 - 2.4e-43 148.1 0.0 3.1e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) CASP_C PF08172.7 EEQ33760.1 - 2.7e-89 298.4 1.5 2.7e-89 298.4 1.0 3.2 3 1 1 4 4 4 1 CASP C terminal Vps39_2 PF10367.4 EEQ33761.1 - 7.5e-08 32.5 0.0 1.8e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EEQ33761.1 - 0.041 13.3 0.0 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 CNH domain DUF605 PF04652.11 EEQ33761.1 - 1.9 7.7 9.8 0.053 12.9 2.1 1.7 2 0 0 2 2 2 0 Vta1 like PALP PF00291.20 EEQ33762.1 - 7.7e-52 176.4 0.2 1.6e-51 175.4 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 EEQ33762.1 - 8.4e-24 84.1 0.1 2.3e-23 82.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEQ33762.1 - 8.3e-18 64.1 0.0 2.4e-17 62.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EEQ33762.1 - 0.0028 16.4 0.0 0.98 8.1 0.0 2.7 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 EEQ33762.1 - 0.0074 16.0 0.1 0.023 14.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 UBA_4 PF14555.1 EEQ33763.1 - 5.2e-11 41.9 0.0 1.1e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EEQ33763.1 - 1.4e-09 37.8 0.0 3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain Ycf1 PF05758.7 EEQ33763.1 - 0.14 9.8 1.8 0.19 9.3 1.2 1.1 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 EEQ33763.1 - 1.1 8.6 6.7 1.8 7.9 4.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.12 EEQ33763.1 - 4.1 7.1 6.8 3 7.5 3.5 1.7 2 0 0 2 2 2 0 DDHD domain LSM PF01423.17 EEQ33765.1 - 3.5e-18 64.8 0.6 4.9e-18 64.4 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEQ33765.1 - 0.057 13.3 0.1 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF4175 PF13779.1 EEQ33765.1 - 1.1 6.8 11.1 1.1 6.8 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 EEQ33765.1 - 1.8 7.3 14.1 0.83 8.4 8.5 1.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor FKBP_N PF01346.13 EEQ33767.1 - 0.28 11.2 10.7 0.86 9.6 5.8 2.5 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Zn_clus PF00172.13 EEQ33767.1 - 0.41 10.6 11.6 1.1 9.1 8.0 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CAF-1_p150 PF11600.3 EEQ33767.1 - 8.3 5.7 31.5 7.2 5.9 1.6 2.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dioxygenase_C PF00775.16 EEQ33768.1 - 1.4e-54 184.1 0.0 2e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EEQ33768.1 - 7e-17 61.1 0.0 1.3e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Ribosomal_L22 PF00237.14 EEQ33769.1 - 2.8e-34 117.1 0.0 4e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e 2-Hacid_dh_C PF02826.14 EEQ33770.1 - 3.2e-57 192.5 0.0 4.7e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ33770.1 - 1.4e-19 69.8 0.0 1.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEQ33770.1 - 0.0001 22.1 0.1 0.00033 20.5 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EEQ33770.1 - 0.0032 17.3 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.22 EEQ33770.1 - 0.082 13.3 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.7 EEQ33771.1 - 6.5e-23 80.5 0.0 1.1e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EEQ33772.1 - 2.9e-23 82.6 0.3 4.6e-23 81.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ33772.1 - 5.2e-12 46.0 0.0 8.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 EEQ33772.1 - 4.8e-11 42.0 0.0 1.3e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.5 EEQ33772.1 - 8.5e-08 32.0 0.2 1.5e-07 31.2 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EEQ33773.1 - 4.5e-32 111.2 1.1 6.3e-32 110.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ33773.1 - 2e-20 73.5 0.0 2.5e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ33773.1 - 5.9e-15 55.3 1.1 1.1e-14 54.4 0.7 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEQ33773.1 - 2.7e-05 23.8 0.6 5.6e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EEQ33773.1 - 4.5e-05 23.0 0.3 6.3e-05 22.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.1 EEQ33773.1 - 0.00016 21.8 0.2 0.26 11.4 0.0 3.0 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain NAD_binding_10 PF13460.1 EEQ33773.1 - 0.0047 16.9 1.6 0.019 14.9 0.8 2.1 1 1 1 2 2 2 1 NADH(P)-binding Glyco_transf_5 PF08323.6 EEQ33773.1 - 0.007 15.8 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain THF_DHG_CYH_C PF02882.14 EEQ33773.1 - 0.0093 15.0 0.2 0.02 13.9 0.1 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 EEQ33773.1 - 0.014 14.8 0.2 0.063 12.7 0.1 1.9 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Ferric_reduct PF01794.14 EEQ33774.1 - 4.4e-22 78.4 7.6 4.4e-22 78.4 5.3 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EEQ33774.1 - 3.1e-16 59.6 0.0 1.2e-13 51.1 0.0 2.8 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ33774.1 - 1.5e-12 47.2 0.0 1.5e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EEQ33774.1 - 0.039 14.5 0.0 1.1 9.8 0.0 2.7 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain GAT PF03127.9 EEQ33775.1 - 1.4e-08 34.5 0.2 6.4e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 GAT domain VHS PF00790.14 EEQ33775.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 VHS domain Pyr_redox_2 PF07992.9 EEQ33776.1 - 2.4e-27 96.1 0.0 3.1e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ33776.1 - 2.9e-11 43.6 0.0 8.7e-10 38.8 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ33776.1 - 0.0059 16.3 0.2 0.1 12.3 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEQ33776.1 - 0.0081 16.2 0.0 0.39 10.7 0.0 2.9 3 2 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EEQ33778.1 - 4.9e-71 239.6 0.0 5.7e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF494 PF04361.8 EEQ33778.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF494) DUF4131 PF13567.1 EEQ33779.1 - 0.013 14.8 0.4 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Fungal_trans_2 PF11951.3 EEQ33780.1 - 0.00053 18.6 0.1 0.0044 15.6 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ33780.1 - 0.00067 19.5 9.0 0.0014 18.4 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Plug_translocon PF10559.4 EEQ33781.1 - 0.052 13.0 0.1 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Plug domain of Sec61p DUF2637 PF10935.3 EEQ33782.1 - 0.12 12.3 0.2 1.3 8.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) Aminotran_1_2 PF00155.16 EEQ33784.1 - 8.8e-18 64.3 0.0 2.2e-14 53.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II PS_Dcarbxylase PF02666.10 EEQ33785.1 - 4.4e-50 169.7 0.0 6.8e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EEQ33785.1 - 2.6e-32 110.5 0.8 1.1e-15 57.2 0.0 3.0 3 0 0 3 3 3 2 C2 domain EF-hand_5 PF13202.1 EEQ33785.1 - 0.012 14.9 0.0 0.036 13.4 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 EEQ33785.1 - 0.03 13.6 0.0 0.086 12.1 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 EEQ33785.1 - 0.08 13.0 0.2 0.23 11.6 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair DUF1212 PF06738.7 EEQ33786.1 - 4.9e-48 163.1 12.6 9.1e-46 155.7 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EEQ33786.1 - 3.1e-26 91.8 34.0 6.8e-26 90.7 13.2 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF3815) Hydrolase_3 PF08282.7 EEQ33787.1 - 9.2e-12 45.0 0.0 2.9e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.8 EEQ33787.1 - 6.1e-09 35.7 0.0 1.2e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.8 EEQ33787.1 - 0.00051 19.4 0.0 0.0046 16.2 0.0 2.2 2 1 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EEQ33787.1 - 0.026 14.6 0.1 0.34 11.0 0.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ33787.1 - 0.042 14.2 0.0 0.064 13.6 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3046 PF11248.3 EEQ33787.1 - 0.062 13.2 0.1 8.3 6.4 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3046) ISN1 PF06437.6 EEQ33787.1 - 0.064 11.9 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Acid_PPase PF12689.2 EEQ33787.1 - 0.11 12.1 0.0 9.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Acid Phosphatase Fox-1_C PF12414.3 EEQ33788.1 - 0.0028 18.0 0.8 0.08 13.3 0.0 2.7 2 0 0 2 2 2 1 Calcitonin gene-related peptide regulator C terminal Ank_2 PF12796.2 EEQ33789.1 - 2.3e-13 50.3 0.2 2.9e-09 37.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ33789.1 - 1.5e-12 46.6 1.2 3.3e-10 39.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EEQ33789.1 - 5.7e-10 38.4 0.2 1.4e-06 27.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EEQ33789.1 - 2e-09 37.6 0.1 1.1e-06 28.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ33789.1 - 5.7e-09 35.9 0.9 6.7e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) NDUF_B7 PF05676.8 EEQ33791.1 - 4.2e-32 109.3 5.1 5e-32 109.1 3.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EEQ33791.1 - 0.022 14.5 2.3 0.033 13.9 1.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GCS PF03074.11 EEQ33792.1 - 1.3e-153 511.5 0.0 1.2e-152 508.2 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.6 EEQ33792.1 - 0.013 15.4 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) UPF0278 PF08745.6 EEQ33792.1 - 0.029 13.6 0.1 0.21 10.7 0.0 2.0 2 0 0 2 2 2 0 UPF0278 family CBS PF00571.23 EEQ33793.1 - 4.2e-23 80.8 0.5 7.6e-05 22.4 0.0 5.5 5 0 0 5 5 5 5 CBS domain WaaY PF06176.6 EEQ33795.1 - 0.072 12.2 0.1 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF3435 PF11917.3 EEQ33796.1 - 9.7e-11 41.0 5.3 1.3e-10 40.6 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) FliJ PF02050.11 EEQ33796.1 - 0.031 14.3 2.3 0.043 13.8 1.6 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein DUF848 PF05852.6 EEQ33796.1 - 0.032 14.0 3.5 0.071 12.9 2.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) CDC37_N PF03234.9 EEQ33796.1 - 0.079 13.2 2.9 0.1 12.8 2.0 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding APG6 PF04111.7 EEQ33796.1 - 0.27 10.2 3.2 0.37 9.7 2.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EEQ33796.1 - 0.33 10.5 2.3 0.41 10.2 1.6 1.2 1 0 0 1 1 1 0 IncA protein Phage_GPO PF05929.6 EEQ33796.1 - 0.85 8.8 3.7 0.86 8.8 2.1 1.3 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Pkinase PF00069.20 EEQ33797.1 - 4.1e-24 85.1 0.0 9.7e-20 70.7 0.0 2.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33797.1 - 0.00048 19.2 0.0 0.0066 15.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase HemX PF04375.9 EEQ33799.1 - 0.00075 18.1 1.4 0.0011 17.6 1.0 1.2 1 0 0 1 1 1 1 HemX CtIP_N PF10482.4 EEQ33799.1 - 0.025 14.3 2.6 0.054 13.2 1.8 1.6 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain LMSTEN PF07988.7 EEQ33799.1 - 0.061 12.6 0.1 0.15 11.3 0.1 1.7 1 0 0 1 1 1 0 LMSTEN motif IncA PF04156.9 EEQ33799.1 - 0.1 12.2 3.1 0.19 11.2 2.2 1.5 1 0 0 1 1 1 0 IncA protein FAM91_C PF14648.1 EEQ33799.1 - 0.12 11.2 0.5 0.21 10.3 0.4 1.3 1 0 0 1 1 1 0 FAM91 C-terminus Atg14 PF10186.4 EEQ33799.1 - 0.15 10.9 5.7 0.2 10.5 4.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF641 PF04859.7 EEQ33799.1 - 0.54 10.0 8.6 1.3 8.7 3.3 2.5 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF2183 PF09949.4 EEQ33800.1 - 6.6e-31 106.2 0.0 2.2e-30 104.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EEQ33800.1 - 0.033 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) ADH_zinc_N_2 PF13602.1 EEQ33801.1 - 4.8e-19 69.5 0.0 8.3e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEQ33801.1 - 0.0024 17.4 0.0 0.004 16.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ33801.1 - 0.0033 17.1 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GPP34 PF05719.6 EEQ33802.1 - 8.3e-65 218.6 0.1 1.1e-64 218.3 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.20 EEQ33803.1 - 3.7e-11 43.1 0.1 5.3e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EEQ33803.1 - 4.8e-05 23.3 0.4 7.5e-05 22.6 0.3 1.4 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EEQ33803.1 - 0.056 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Fer4 PF00037.22 EEQ33804.1 - 1.6e-13 49.6 16.5 5.5e-08 32.0 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EEQ33804.1 - 1.2e-11 44.7 10.4 2e-11 44.1 7.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EEQ33804.1 - 5.6e-10 39.8 7.2 0.00022 21.8 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 EEQ33804.1 - 2.8e-09 37.0 10.8 5e-09 36.2 7.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEQ33804.1 - 3e-09 36.5 22.0 8.9e-08 31.8 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EEQ33804.1 - 2e-08 33.9 21.8 4.5e-06 26.4 8.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EEQ33804.1 - 1.4e-07 30.9 14.7 0.00045 19.9 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EEQ33804.1 - 1.4e-07 31.3 20.1 3.2e-05 23.8 7.9 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EEQ33804.1 - 2.7e-07 30.1 17.1 0.0013 18.5 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EEQ33804.1 - 5.1e-06 26.7 9.1 0.00083 19.6 7.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 EEQ33804.1 - 5.6e-06 26.2 12.7 0.0006 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EEQ33804.1 - 8.3e-05 22.9 9.8 0.024 15.0 0.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EEQ33804.1 - 0.0086 16.4 15.1 0.31 11.4 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EEQ33804.1 - 0.012 16.1 12.8 0.22 12.0 1.0 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EEQ33804.1 - 0.077 13.6 16.9 0.16 12.5 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EEQ33804.1 - 0.17 12.0 4.9 0.2 11.7 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain SURF6 PF04935.7 EEQ33805.1 - 3e-50 170.4 33.0 3e-50 170.4 22.8 4.1 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EEQ33805.1 - 1.3e-22 79.6 0.6 1.3e-22 79.6 0.4 8.4 7 2 1 8 8 8 1 60S ribosome biogenesis protein Rrp14 Rick_17kDa_Anti PF05433.10 EEQ33806.1 - 0.012 15.2 17.2 0.012 15.2 11.9 2.1 3 0 0 3 3 3 0 Glycine zipper 2TM domain TraT PF05818.7 EEQ33806.1 - 1.3 8.4 3.7 2.8 7.2 2.6 1.6 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF456 PF04306.8 EEQ33806.1 - 1.3 9.0 4.9 1.8 8.5 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF4190 PF13828.1 EEQ33806.1 - 2.5 7.7 9.6 0.71 9.4 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4190) Acyl_transf_3 PF01757.17 EEQ33808.1 - 1.7e-39 135.6 31.2 2e-39 135.3 21.6 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.10 EEQ33809.1 - 5.3e-12 46.0 0.2 1.1e-11 45.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ribosomal_S2 PF00318.15 EEQ33810.1 - 4.3e-50 169.8 0.0 8.7e-50 168.8 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S2 Mito_carr PF00153.22 EEQ33812.1 - 1.4e-58 194.6 0.3 1.5e-21 75.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.22 EEQ33813.1 - 1.7e-37 128.7 4.4 1e-36 126.1 3.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EEQ33813.1 - 3.2e-26 91.3 1.3 3.2e-26 91.3 0.9 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EEQ33813.1 - 2.5e-12 46.7 0.6 2.7e-06 27.4 0.0 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ33813.1 - 4.3e-08 33.1 0.1 1.1e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 EEQ33813.1 - 9e-08 31.6 0.0 3.8e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 EEQ33813.1 - 2.9e-06 27.7 0.1 6.4e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ33813.1 - 0.00013 21.2 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ33813.1 - 0.00016 20.9 0.1 0.00036 19.7 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EEQ33813.1 - 0.0024 17.3 0.1 0.0059 16.1 0.1 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EEQ33813.1 - 0.0062 16.3 1.3 2.4 7.9 0.0 3.2 2 1 1 3 3 3 2 Dynamin family Ras PF00071.17 EEQ33813.1 - 0.013 14.8 0.2 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Ras family FeoB_N PF02421.13 EEQ33813.1 - 0.014 14.7 0.4 0.046 12.9 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B DZR PF12773.2 EEQ33813.1 - 0.11 12.3 1.0 0.27 11.0 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon HNH PF01844.18 EEQ33815.1 - 0.0011 18.7 4.4 0.002 17.9 3.1 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF1364 PF07102.7 EEQ33815.1 - 0.027 14.3 0.4 0.052 13.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) EI24 PF07264.6 EEQ33816.1 - 3.7e-05 23.2 0.5 3.7e-05 23.2 0.4 2.4 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Ceramidase_alk PF04734.8 EEQ33818.1 - 1.9e-267 888.5 0.0 2.2e-267 888.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase BCAS2 PF05700.6 EEQ33819.1 - 2.3e-52 177.6 0.1 2.5e-52 177.5 0.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Kelch_5 PF13854.1 EEQ33820.1 - 2.3e-16 59.3 14.7 2.6e-09 36.8 0.1 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EEQ33820.1 - 3.3e-12 45.9 13.6 0.013 15.2 0.2 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EEQ33820.1 - 4.2e-11 42.6 6.3 5.1e-06 26.4 0.1 5.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EEQ33820.1 - 1.2e-09 37.9 10.4 0.0028 17.7 0.2 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EEQ33820.1 - 7.9e-05 22.2 2.7 0.27 11.0 0.1 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 EEQ33820.1 - 0.0022 17.4 6.9 1.4 8.5 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Ten1 PF12658.2 EEQ33821.1 - 3.4e-42 143.1 0.0 4e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EEQ33821.1 - 8.3e-05 22.1 0.0 0.00034 20.1 0.0 1.8 1 1 1 2 2 2 1 Telomere-capping, CST complex subunit YfkB PF08756.5 EEQ33821.1 - 0.073 12.6 0.0 0.095 12.2 0.0 1.1 1 0 0 1 1 1 0 YfkB-like domain Snf7 PF03357.16 EEQ33823.1 - 1.7e-32 112.1 16.4 1.7e-32 112.1 11.4 2.0 1 1 1 2 2 2 1 Snf7 PTSIIB_sorb PF03830.10 EEQ33823.1 - 0.012 15.5 1.4 0.018 14.9 1.0 1.4 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component Calici_MSP PF05752.6 EEQ33823.1 - 0.067 12.7 4.5 0.11 12.0 3.2 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein Allexi_40kDa PF05549.6 EEQ33823.1 - 0.42 9.8 7.1 0.45 9.7 4.3 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein MutS_III PF05192.13 EEQ33823.1 - 1.2 8.9 4.8 1.6 8.4 3.3 1.4 1 1 0 1 1 1 0 MutS domain III DUF3138 PF11336.3 EEQ33823.1 - 5.5 5.0 5.9 2.1 6.4 2.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Fork_head PF00250.13 EEQ33824.1 - 5.4e-17 61.6 0.1 9.3e-17 60.8 0.1 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EEQ33824.1 - 0.00044 20.2 0.0 0.00085 19.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_3 PF13640.1 EEQ33825.1 - 1.4e-11 44.8 0.0 2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EEQ33825.1 - 1e-08 34.7 0.0 2.6e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EEQ33825.1 - 6.4e-05 23.1 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily cNMP_binding PF00027.24 EEQ33826.1 - 6.2e-42 141.3 0.0 3e-20 71.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain FAD_binding_8 PF08022.7 EEQ33828.1 - 5.2e-15 55.1 0.0 1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EEQ33828.1 - 8.7e-13 48.4 7.9 8.7e-13 48.4 5.5 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EEQ33828.1 - 7.4e-12 45.4 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Mito_carr PF00153.22 EEQ33829.1 - 2.1e-42 142.7 9.4 2.7e-17 62.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.7 EEQ33830.1 - 7.5e-26 90.0 5.8 1.2e-25 89.3 4.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ33830.1 - 1.2e-13 50.7 0.0 1.8e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEQ33830.1 - 0.00067 18.8 0.1 0.001 18.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EEQ33830.1 - 0.0016 18.1 0.1 0.0025 17.4 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GCC2_GCC3 PF07699.8 EEQ33830.1 - 0.014 14.9 0.7 0.091 12.3 0.2 2.3 2 0 0 2 2 2 0 GCC2 and GCC3 ADH_zinc_N_2 PF13602.1 EEQ33830.1 - 0.03 15.2 0.0 0.053 14.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.2 EEQ33831.1 - 4.6e-32 111.7 0.2 5.8e-32 111.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ33831.1 - 3.4e-17 62.7 0.1 6.9e-17 61.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ33831.1 - 1.5e-10 40.9 0.0 3.6e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEQ33831.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EEQ33831.1 - 0.041 12.3 0.0 0.14 10.6 0.0 1.7 2 0 0 2 2 2 0 Ndr family Sugar_tr PF00083.19 EEQ33832.1 - 1.8e-69 234.4 27.8 7.7e-36 123.6 6.9 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ33832.1 - 3.9e-26 91.6 36.3 6.4e-19 67.8 11.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2306 PF10067.4 EEQ33833.1 - 4.6e-12 45.9 2.0 4.6e-12 45.9 1.4 2.1 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) DUF898 PF05987.8 EEQ33833.1 - 0.013 14.3 2.3 0.021 13.7 1.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF420 PF04238.7 EEQ33833.1 - 0.042 13.7 5.5 0.05 13.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF420) APH PF01636.18 EEQ33834.1 - 1.5e-11 44.5 0.0 1.3e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ33834.1 - 3.8e-05 22.5 0.3 0.0049 15.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEQ33834.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Inos-1-P_synth PF01658.12 EEQ33834.1 - 0.25 11.1 2.0 0.26 11.1 0.0 2.0 3 0 0 3 3 3 0 Myo-inositol-1-phosphate synthase GST_C PF00043.20 EEQ33837.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NADHdh_A3 PF14987.1 EEQ33840.1 - 0.015 15.2 0.3 0.018 14.9 0.2 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DDOST_48kD PF03345.9 EEQ33841.1 - 8.2e-164 545.1 0.0 9.2e-164 544.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pet191_N PF10203.4 EEQ33842.1 - 3.7e-27 94.1 6.1 4.7e-27 93.8 4.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EEQ33842.1 - 0.012 15.3 5.0 1.3 8.8 0.2 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_3 PF08277.7 EEQ33842.1 - 0.016 14.7 0.3 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain COBRA PF04833.10 EEQ33842.1 - 0.06 13.1 0.3 0.065 12.9 0.2 1.2 1 0 0 1 1 1 0 COBRA-like protein Abhydro_lipase PF04083.11 EEQ33843.1 - 1.4e-23 82.0 0.2 2.9e-23 80.9 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EEQ33843.1 - 1.9e-19 70.1 0.6 2.8e-19 69.6 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ33843.1 - 3.5e-06 27.0 0.1 5.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ33843.1 - 2.4e-05 24.1 0.0 7.4e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EEQ33843.1 - 7.9e-05 22.2 0.1 0.08 12.3 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EEQ33843.1 - 0.12 11.7 0.2 16 4.8 0.1 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ras PF00071.17 EEQ33845.1 - 6.9e-29 100.3 0.3 2e-28 98.8 0.2 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEQ33845.1 - 7.5e-11 42.5 0.6 3e-10 40.6 0.4 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ33845.1 - 3.7e-05 23.0 0.0 0.00016 20.9 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ33845.1 - 0.0073 15.7 0.0 0.29 10.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EEQ33845.1 - 0.087 12.7 0.4 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EEQ33845.1 - 0.23 11.6 1.7 6.2 6.9 1.0 2.4 1 1 0 1 1 1 0 AAA domain Carboxyl_trans PF01039.17 EEQ33846.1 - 1.8e-144 481.7 0.0 2.3e-144 481.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EEQ33846.1 - 0.025 13.7 0.0 2.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) DUF1657 PF07870.6 EEQ33846.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) Acyl-CoA_dh_1 PF00441.19 EEQ33847.1 - 1.6e-39 135.4 1.9 1.6e-39 135.3 0.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ33847.1 - 7e-35 120.0 0.1 1.7e-34 118.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ33847.1 - 1.8e-20 72.1 0.3 5.5e-20 70.6 0.1 1.9 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEQ33847.1 - 3.9e-15 56.2 0.5 7.7e-15 55.3 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EEQ33847.1 - 0.0023 17.3 0.7 0.0095 15.3 0.5 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CPSase_L_D2 PF02786.12 EEQ33849.1 - 1.8e-73 246.3 0.0 2.6e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EEQ33849.1 - 1.2e-35 121.7 0.0 2.5e-35 120.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EEQ33849.1 - 3.3e-33 114.0 0.0 9.6e-33 112.5 0.0 1.8 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EEQ33849.1 - 1.5e-17 63.9 0.0 4.2e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EEQ33849.1 - 4.5e-16 58.2 2.1 1.3e-15 56.8 1.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EEQ33849.1 - 2.8e-12 46.0 0.0 4.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEQ33849.1 - 6.3e-10 38.7 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EEQ33849.1 - 3.4e-07 29.7 0.0 7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EEQ33849.1 - 6.2e-07 28.9 0.1 0.018 14.7 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EEQ33849.1 - 4.6e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EEQ33849.1 - 0.001 19.4 0.1 0.24 11.7 0.0 2.9 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 EEQ33849.1 - 0.0059 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 EEQ33849.1 - 0.0079 15.8 0.2 0.023 14.4 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein RimK PF08443.6 EEQ33849.1 - 0.039 13.4 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain HlyD PF00529.15 EEQ33849.1 - 0.05 12.8 0.8 2.9 7.1 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 EEQ33849.1 - 0.054 12.5 0.0 0.14 11.1 0.0 1.7 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp adh_short_C2 PF13561.1 EEQ33850.1 - 4.1e-26 92.2 0.0 5.1e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ33850.1 - 1.4e-19 70.6 0.1 2e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ33850.1 - 6.1e-11 42.3 0.1 9.2e-11 41.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ33850.1 - 0.017 14.5 0.1 0.051 13.0 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Coatomer_E PF04733.9 EEQ33850.1 - 0.078 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit Chrome_Resist PF09828.4 EEQ33850.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Chromate resistance exported protein DUF1752 PF08550.5 EEQ33852.1 - 5e-10 38.7 3.4 9.3e-10 37.9 2.3 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SSP160 PF06933.6 EEQ33852.1 - 1.3 6.9 9.4 1.8 6.4 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NST1 PF13945.1 EEQ33852.1 - 2 8.4 6.7 4.9 7.1 4.7 1.7 1 0 0 1 1 1 0 Salt tolerance down-regulator MARVEL PF01284.18 EEQ33853.1 - 8.1e-10 38.6 3.4 1.3e-09 38.0 2.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain Plasmodium_Vir PF05795.6 EEQ33855.1 - 0.044 13.0 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PHD PF00628.24 EEQ33856.1 - 6e-10 38.6 1.5 6e-10 38.6 1.1 1.6 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EEQ33856.1 - 0.00095 18.4 2.6 0.0015 17.8 1.8 1.3 1 0 0 1 1 1 1 PHD-finger F-box-like_2 PF13013.1 EEQ33857.1 - 0.036 13.7 2.5 0.092 12.4 1.7 2.0 1 1 0 1 1 1 0 F-box-like domain Glyco_hydro_18 PF00704.23 EEQ33860.1 - 1.3e-54 186.0 0.0 1.8e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EEQ33860.1 - 1.7e-06 27.8 28.4 2e-05 24.4 4.8 4.6 5 0 0 5 5 5 2 Chitin recognition protein MFS_1 PF07690.11 EEQ33861.1 - 2.1e-21 76.0 44.6 2.5e-15 56.0 26.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2755 PF10954.3 EEQ33861.1 - 1.4 8.6 5.1 43 3.9 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2755) NAD_binding_10 PF13460.1 EEQ33862.1 - 0.00012 22.1 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 2 NADH(P)-binding RmlD_sub_bind PF04321.12 EEQ33862.1 - 0.042 12.7 0.0 0.32 9.8 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 EEQ33863.1 - 9.1e-40 136.2 0.0 2.9e-39 134.6 0.0 1.9 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EEQ33863.1 - 4.4e-34 117.5 0.0 1e-33 116.2 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EEQ33863.1 - 9.4e-33 113.4 0.1 4.5e-32 111.2 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.16 EEQ33863.1 - 1.7e-05 24.3 0.0 6.4e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EEQ33863.1 - 0.00021 21.4 0.2 0.00052 20.2 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site F-box-like_2 PF13013.1 EEQ33864.1 - 0.0025 17.5 0.2 0.0068 16.1 0.2 1.7 1 1 0 1 1 1 1 F-box-like domain eIF-5a PF01287.15 EEQ33865.1 - 0.00055 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold MFS_1 PF07690.11 EEQ33866.1 - 9.4e-31 106.7 16.7 9.4e-31 106.7 11.6 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ33866.1 - 7.5e-05 21.4 6.5 7.5e-05 21.4 4.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EEQ33866.1 - 0.0022 16.1 0.6 0.099 10.6 0.5 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3353 PF11833.3 EEQ33866.1 - 0.29 10.5 5.7 0.055 12.9 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) PgaD PF13994.1 EEQ33866.1 - 0.97 8.9 3.1 1 8.8 0.0 2.2 2 0 0 2 2 2 0 PgaD-like protein YhhN PF07947.9 EEQ33867.1 - 4.1e-42 143.6 3.7 5.4e-42 143.2 2.6 1.2 1 0 0 1 1 1 1 YhhN-like protein TMEM213 PF15192.1 EEQ33867.1 - 0.059 13.3 0.4 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 TMEM213 family InaF-motif PF15018.1 EEQ33867.1 - 0.38 10.2 2.8 1.4 8.4 1.9 2.0 1 0 0 1 1 1 0 TRP-interacting helix Abhydrolase_6 PF12697.2 EEQ33869.1 - 4.4e-31 108.5 3.9 1.3e-30 106.9 2.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ33869.1 - 6e-14 52.1 0.1 3.3e-09 36.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ33869.1 - 7e-11 42.0 0.0 1.1e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEQ33869.1 - 9.7e-08 31.7 0.0 3.5e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EEQ33869.1 - 0.0028 16.9 0.0 0.018 14.2 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 EEQ33869.1 - 0.02 14.3 0.1 0.088 12.2 0.0 1.8 1 1 0 1 1 1 0 Putative esterase SRR1 PF07985.7 EEQ33872.1 - 5.2e-12 45.5 0.0 8.4e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.2 EEQ33872.1 - 0.035 14.1 0.2 0.079 12.9 0.1 1.6 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Glyco_hydro_17 PF00332.13 EEQ33875.1 - 3.8e-09 36.0 1.7 9.2e-06 24.9 0.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Scytalone_dh PF02982.9 EEQ33876.1 - 6.9e-63 210.9 1.1 1.2e-62 210.1 0.7 1.4 1 1 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EEQ33876.1 - 0.0016 18.3 0.5 0.0024 17.7 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 EEQ33876.1 - 0.19 11.7 2.4 3.3 7.7 0.1 2.3 2 1 0 2 2 2 0 SnoaL-like domain NAD_binding_10 PF13460.1 EEQ33877.1 - 7.4e-15 55.4 0.0 9.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEQ33877.1 - 1.6e-06 27.5 0.0 3.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EEQ33877.1 - 0.00045 19.0 0.1 0.00066 18.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEQ33877.1 - 0.0055 16.1 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEQ33877.1 - 0.024 13.5 0.0 0.082 11.8 0.0 1.8 1 1 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 EEQ33877.1 - 0.029 13.2 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EEQ33877.1 - 0.046 14.0 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF4243 PF14027.1 EEQ33878.1 - 3.2e-93 312.7 0.6 3.9e-93 312.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) EthD PF07110.6 EEQ33879.1 - 9.8e-19 68.0 0.1 1.3e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.11 EEQ33880.1 - 4.3e-43 147.3 49.6 4.3e-43 147.3 34.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EEQ33881.1 - 1.2e-18 66.9 0.0 1.6e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AflR PF08493.5 EEQ33882.1 - 1.7e-14 53.5 12.1 6.4e-14 51.6 8.4 1.9 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EEQ33882.1 - 4.7e-05 23.2 10.5 9.2e-05 22.2 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_11 PF08241.7 EEQ33883.1 - 9.2e-10 38.8 0.0 1.7e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ33883.1 - 5e-08 32.6 0.0 7.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ33883.1 - 1.2e-05 25.8 0.1 2.7e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ33883.1 - 1.7e-05 25.2 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ33883.1 - 0.00086 19.6 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ33883.1 - 0.0042 16.8 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ33883.1 - 0.0051 16.2 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 EEQ33883.1 - 0.01 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase SnoaL_2 PF12680.2 EEQ33885.1 - 0.00029 21.2 0.0 0.0004 20.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain adh_short PF00106.20 EEQ33886.1 - 5.9e-32 110.8 1.2 7.9e-32 110.4 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ33886.1 - 3.9e-30 105.3 0.7 4.8e-30 105.1 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ33886.1 - 9.6e-17 61.2 1.1 1.3e-16 60.7 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ33886.1 - 0.00033 20.1 0.4 0.0013 18.2 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EEQ33886.1 - 0.0081 15.3 0.0 0.013 14.6 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF460 PF04312.8 EEQ33886.1 - 0.023 14.2 0.2 0.06 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF460) 2-Hacid_dh_C PF02826.14 EEQ33886.1 - 0.12 11.5 0.4 0.27 10.3 0.3 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 EEQ33887.1 - 5e-14 52.3 0.1 1.1e-07 31.6 0.0 2.3 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEQ33887.1 - 2.4e-08 33.8 0.0 9.4e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain zf-DHHC PF01529.15 EEQ33890.1 - 3.5e-25 88.4 8.9 3.5e-25 88.4 6.1 2.6 1 1 1 2 2 2 1 DHHC palmitoyltransferase Fungal_trans PF04082.13 EEQ33891.1 - 3.3e-11 42.5 0.1 8e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ33891.1 - 1.7e-06 27.8 12.2 3.2e-06 26.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.12 EEQ33892.1 - 8.8e-29 97.0 14.9 0.00051 19.7 0.2 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ33892.1 - 1.9e-27 94.7 20.0 1.1e-09 37.7 0.1 8.4 6 2 0 7 7 7 4 TPR repeat TPR_1 PF00515.23 EEQ33892.1 - 6e-25 85.7 13.2 0.00032 20.1 0.6 10.4 11 0 0 11 11 11 6 Tetratricopeptide repeat Apc3 PF12895.2 EEQ33892.1 - 1.7e-24 85.7 17.4 5.4e-20 71.3 1.3 6.0 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEQ33892.1 - 1.9e-15 56.5 27.8 5.3e-08 32.6 0.5 8.9 6 3 1 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33892.1 - 8.3e-13 48.4 14.3 0.00046 20.4 0.0 7.8 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ33892.1 - 1.7e-12 46.1 9.1 0.046 13.5 0.1 8.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ33892.1 - 1e-11 44.3 18.2 0.24 12.1 0.2 9.3 6 3 4 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ33892.1 - 4.9e-10 39.8 31.0 0.0013 19.3 0.2 9.0 8 2 2 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ33892.1 - 2.6e-06 26.8 22.6 3.3 7.7 0.1 9.8 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ33892.1 - 2.1e-05 24.3 13.2 0.82 10.0 0.0 8.5 10 1 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ33892.1 - 4.8e-05 23.5 10.2 4.3 8.0 0.1 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ33892.1 - 0.0019 18.0 24.5 0.023 14.6 0.0 7.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ33892.1 - 0.073 13.5 11.4 1.5 9.4 0.7 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 EEQ33892.1 - 0.093 12.6 6.0 36 4.2 0.0 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat Trefoil PF00088.13 EEQ33892.1 - 0.32 10.6 2.3 0.67 9.6 1.6 1.5 1 0 0 1 1 1 0 Trefoil (P-type) domain TPR_9 PF13371.1 EEQ33892.1 - 0.4 10.5 13.5 3.8 7.4 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF572 PF04502.8 EEQ33893.1 - 2.2e-71 240.7 12.2 2.8e-71 240.4 8.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 EEQ33893.1 - 0.0038 17.0 0.2 0.0067 16.2 0.1 1.3 1 0 0 1 1 1 1 Benyvirus 14KDa protein DUF866 PF05907.8 EEQ33893.1 - 0.011 15.2 2.0 0.014 14.8 0.8 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-FCS PF06467.9 EEQ33893.1 - 0.045 13.4 3.2 0.22 11.2 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_5 PF13719.1 EEQ33893.1 - 0.059 12.9 0.4 9.8 5.8 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EEQ33893.1 - 0.071 12.4 3.8 0.76 9.1 1.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 EEQ33893.1 - 0.084 12.5 0.4 9.4 6.0 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EEQ33893.1 - 0.11 11.7 0.3 0.52 9.5 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EEQ33893.1 - 0.16 11.4 2.0 12 5.4 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit FAT PF02259.18 EEQ33894.1 - 3e-73 246.8 12.3 6.1e-73 245.8 8.5 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EEQ33894.1 - 1.3e-29 103.3 0.3 4.8e-29 101.4 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EEQ33894.1 - 5.7e-09 35.2 0.1 1.5e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 FATC domain B56 PF01603.15 EEQ33895.1 - 8.1e-137 456.1 7.2 2.5e-106 355.7 1.9 2.1 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.18 EEQ33895.1 - 0.075 12.8 0.3 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Tau95 PF09734.4 EEQ33896.1 - 4.9e-71 239.6 0.0 6.4e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Nop14 PF04147.7 EEQ33896.1 - 1.1 7.1 8.0 1.3 6.8 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EEQ33896.1 - 3.5 6.7 9.7 5.1 6.2 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein Soyouz_module PF14313.1 EEQ33897.1 - 0.056 13.0 1.6 0.21 11.2 0.1 2.8 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) ATP-grasp_4 PF13535.1 EEQ33898.1 - 1.2e-24 87.1 0.0 2.6e-21 76.1 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEQ33898.1 - 1e-08 34.8 0.0 3.9e-08 32.9 0.0 2.0 3 0 0 3 3 3 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EEQ33898.1 - 9.4e-06 24.5 0.0 0.0033 16.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EEQ33898.1 - 4.7e-05 23.3 0.0 0.0005 19.9 0.0 2.3 3 0 0 3 3 3 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EEQ33898.1 - 0.00016 20.9 0.0 0.0004 19.7 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EEQ33898.1 - 0.001 18.5 0.0 0.0038 16.7 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EEQ33898.1 - 0.0019 17.7 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PfkB PF00294.19 EEQ33899.1 - 3.8e-39 134.6 0.0 7e-39 133.7 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase ECH PF00378.15 EEQ33900.1 - 3e-38 131.3 0.0 5.2e-37 127.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Antimicrobial_1 PF08018.6 EEQ33900.1 - 0.54 10.2 2.4 2.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Frog antimicrobial peptide MCM PF00493.18 EEQ33901.1 - 1.4e-141 471.1 0.2 1.8e-141 470.7 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEQ33901.1 - 2.2e-18 66.9 0.4 6e-18 65.4 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ33901.1 - 8.6e-07 28.3 0.0 0.00014 21.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ33901.1 - 2.2e-05 24.2 0.0 4.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEQ33901.1 - 0.0012 18.4 0.1 0.0048 16.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEQ33901.1 - 0.018 14.5 0.1 0.24 10.8 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 EEQ33901.1 - 0.048 14.0 0.4 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Lon_2 PF13337.1 EEQ33901.1 - 0.05 11.9 0.2 0.5 8.6 0.0 2.0 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease AAA PF00004.24 EEQ33901.1 - 0.11 12.7 0.1 0.81 9.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Vps54 PF07928.7 EEQ33904.1 - 5.5e-47 159.2 0.0 1.4e-46 157.9 0.0 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EEQ33904.1 - 3.9e-06 25.9 0.3 2.1e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EEQ33904.1 - 0.00042 20.1 0.1 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Cytochrom_B562 PF07361.6 EEQ33904.1 - 0.02 15.2 0.2 0.078 13.3 0.1 2.0 1 0 0 1 1 1 0 Cytochrome b562 COG2 PF06148.6 EEQ33904.1 - 0.091 12.6 1.7 0.34 10.7 1.2 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Hid1 PF12722.2 EEQ33907.1 - 6.4e-262 871.2 0.0 1.5e-260 866.7 0.0 2.2 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EEQ33907.1 - 1.9e-64 218.0 0.0 9.1e-42 143.0 0.0 2.2 2 0 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein BC10 PF06726.7 EEQ33907.1 - 0.056 13.4 0.1 0.19 11.7 0.1 2.0 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 Cupin_2 PF07883.6 EEQ33909.1 - 2.8e-06 26.7 0.0 4.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain KAT11 PF08214.6 EEQ33910.1 - 1.2e-92 310.7 0.0 1.5e-92 310.4 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein DUF2255 PF10012.4 EEQ33910.1 - 0.013 15.4 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) E1-E2_ATPase PF00122.15 EEQ33911.1 - 1.7e-49 167.9 1.4 4.3e-49 166.6 1.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ33911.1 - 2.3e-38 131.5 17.1 8.4e-38 129.7 3.9 3.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ33911.1 - 4.3e-31 109.0 0.0 4.3e-30 105.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ33911.1 - 3.1e-18 66.6 0.0 7.9e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ33911.1 - 5.5e-18 64.7 0.0 1.1e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEQ33911.1 - 2e-13 49.5 0.2 6e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEQ33911.1 - 9.9e-07 28.5 0.4 4.7e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1625 PF07787.7 EEQ33911.1 - 0.04 13.1 4.2 2.7 7.1 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) DUF2207 PF09972.4 EEQ33911.1 - 0.62 8.5 6.8 2 6.9 0.1 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Glyco_transf_21 PF13506.1 EEQ33913.1 - 1.8e-11 43.6 0.0 2.4e-05 23.6 0.0 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EEQ33913.1 - 4.5e-11 42.9 0.0 8.2e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF2621 PF11084.3 EEQ33913.1 - 0.14 11.8 1.9 0.57 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) Ank_2 PF12796.2 EEQ33914.1 - 1.1e-15 57.6 0.3 9.7e-15 54.6 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ33914.1 - 1.3e-14 53.1 0.8 2.2e-10 39.8 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EEQ33914.1 - 2.6e-13 49.7 0.5 3.5e-08 33.4 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ33914.1 - 5.5e-12 44.6 1.1 4.7e-07 29.4 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EEQ33914.1 - 5.2e-10 39.5 0.4 6.1e-09 36.1 0.2 2.7 2 1 0 2 2 2 1 Ankyrin repeats (many copies) WW PF00397.21 EEQ33915.1 - 7.7e-08 32.0 1.0 1.9e-07 30.8 0.7 1.6 1 0 0 1 1 1 1 WW domain Hydrophobin PF01185.13 EEQ33916.1 - 5.9e-10 39.4 12.5 8.2e-10 39.0 8.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin NMO PF03060.10 EEQ33918.1 - 1.3e-64 218.4 0.1 1.6e-64 218.1 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEQ33918.1 - 3.5e-11 42.6 0.0 0.0001 21.3 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEQ33918.1 - 0.0036 16.1 0.4 0.0073 15.1 0.3 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 EEQ33918.1 - 0.0082 15.1 0.1 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase DUF1902 PF08972.6 EEQ33918.1 - 0.15 11.6 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Sdh_cyt PF01127.17 EEQ33919.1 - 5.6e-24 84.2 3.9 9.8e-24 83.5 2.7 1.4 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CybS PF05328.7 EEQ33919.1 - 0.071 12.7 0.3 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 CybS Ribonucleas_3_3 PF14622.1 EEQ33920.1 - 1.2e-22 80.2 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EEQ33920.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III domain Adap_comp_sub PF00928.16 EEQ33921.1 - 2.6e-89 298.8 0.0 3.3e-89 298.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEQ33921.1 - 2.9e-09 36.7 0.1 4.8e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EEQ33921.1 - 0.072 12.2 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain ABC2_membrane PF01061.19 EEQ33924.1 - 4.9e-83 277.4 46.7 1.6e-44 151.5 8.5 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EEQ33924.1 - 4.7e-34 117.6 0.0 1.8e-17 63.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEQ33924.1 - 1.2e-23 82.7 1.7 1.3e-20 72.9 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EEQ33924.1 - 1e-06 28.7 0.0 5.7e-06 26.3 0.0 2.4 3 0 0 3 3 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EEQ33924.1 - 7.9e-06 25.1 44.0 0.001 18.1 5.0 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EEQ33924.1 - 9.9e-06 25.7 0.3 0.098 12.6 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EEQ33924.1 - 0.0001 22.2 0.1 0.0048 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEQ33924.1 - 0.00039 19.8 0.1 0.01 15.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EEQ33924.1 - 0.00045 19.6 0.4 0.004 16.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ33924.1 - 0.00088 19.3 0.1 0.031 14.2 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 EEQ33924.1 - 0.0014 17.8 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ33924.1 - 0.0042 17.9 0.0 0.11 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EEQ33924.1 - 0.0043 17.0 0.2 0.041 13.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEQ33924.1 - 0.0056 16.8 0.2 0.054 13.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EEQ33924.1 - 0.007 15.9 0.9 0.76 9.4 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 EEQ33924.1 - 0.0089 15.2 0.0 0.22 10.7 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 EEQ33924.1 - 0.024 14.3 0.2 4.2 7.1 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 EEQ33924.1 - 0.029 13.8 1.9 0.03 13.7 0.4 1.7 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EEQ33924.1 - 0.054 13.8 0.1 0.53 10.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EEQ33924.1 - 0.12 12.8 0.0 5.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 EEQ33924.1 - 0.13 11.7 0.8 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-grasp_5 PF13549.1 EEQ33924.1 - 0.14 11.3 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain MFS_1 PF07690.11 EEQ33925.1 - 5.1e-38 130.7 22.9 5.2e-37 127.3 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EEQ33925.1 - 2.4 8.2 7.8 0.48 10.4 0.3 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) TraL PF07178.6 EEQ33925.1 - 2.6 8.1 11.7 9 6.3 0.0 4.4 3 1 2 5 5 5 0 TraL protein ABC_tran PF00005.22 EEQ33926.1 - 4.2e-50 169.5 0.0 6.6e-25 88.0 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 EEQ33926.1 - 9.6e-26 90.6 52.2 2.7e-17 62.8 19.3 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EEQ33926.1 - 3.5e-22 79.7 0.1 0.00012 22.2 0.0 4.5 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EEQ33926.1 - 6.7e-10 38.3 6.7 1.6e-05 24.3 0.3 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 EEQ33926.1 - 1.1e-09 37.8 1.0 0.006 15.8 0.0 3.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEQ33926.1 - 1.7e-09 38.3 2.3 0.00055 20.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEQ33926.1 - 1.5e-05 24.2 0.1 0.022 13.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ33926.1 - 0.00022 21.2 0.1 0.75 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EEQ33926.1 - 0.00024 20.2 0.0 0.11 11.5 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.1 EEQ33926.1 - 0.0035 17.3 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF4162 PF13732.1 EEQ33926.1 - 0.0055 17.1 0.0 0.022 15.2 0.0 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF4162) AAA_30 PF13604.1 EEQ33926.1 - 0.0056 16.2 1.3 0.72 9.3 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EEQ33926.1 - 0.0061 15.9 2.5 1.3 8.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ33926.1 - 0.015 15.2 0.2 3.7 7.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EEQ33926.1 - 0.021 13.8 1.0 3.8 6.5 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin SbcCD_C PF13558.1 EEQ33926.1 - 0.034 14.0 0.3 14 5.7 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 EEQ33926.1 - 0.046 13.1 0.6 7.3 5.9 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MutS_V PF00488.16 EEQ33926.1 - 0.053 12.9 0.0 2.6 7.4 0.0 2.8 3 0 0 3 3 3 0 MutS domain V AAA_10 PF12846.2 EEQ33926.1 - 0.064 12.6 0.0 7.2 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 EEQ33926.1 - 0.066 13.3 0.3 11 6.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EEQ33926.1 - 0.084 11.3 0.1 1.3 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEQ33926.1 - 0.092 12.5 1.6 12 5.7 0.1 2.9 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EEQ33926.1 - 0.15 11.5 0.2 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family G-alpha PF00503.15 EEQ33926.1 - 0.36 9.4 0.0 4 6.0 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 EEQ33926.1 - 0.73 9.7 1.9 29 4.5 0.2 2.6 2 0 0 2 2 2 0 AAA domain Peptidase_M18 PF02127.10 EEQ33927.1 - 4.7e-131 437.2 0.0 5.8e-131 436.9 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EEQ33927.1 - 0.00077 18.3 0.0 0.35 9.6 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase NOB1_Zn_bind PF08772.6 EEQ33928.1 - 9.2e-27 92.6 5.1 1.5e-26 92.0 2.6 1.9 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EEQ33928.1 - 0.0045 16.4 0.5 0.0045 16.4 0.3 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain AF1Q PF15017.1 EEQ33928.1 - 6.7 6.6 19.3 1.5 8.8 9.2 2.8 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator Nop10p PF04135.7 EEQ33929.1 - 3.6e-21 74.6 0.2 4.2e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family tRNA_int_endo PF01974.12 EEQ33930.1 - 1.2e-19 69.8 0.0 2.4e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EEQ33930.1 - 3.7e-06 26.4 0.0 0.00073 19.0 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Rad9_Rad53_bind PF08605.5 EEQ33931.1 - 7.5e-17 61.3 0.0 1.4e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EEQ33931.1 - 6.2e-08 32.6 0.0 1.8e-06 27.9 0.0 3.3 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Ribosomal_L27 PF01016.14 EEQ33932.1 - 2.9e-31 107.0 1.0 4.8e-31 106.3 0.7 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Scramblase PF03803.10 EEQ33934.1 - 1e-56 191.5 0.0 5.1e-55 185.9 0.0 2.7 1 1 0 1 1 1 1 Scramblase UQ_con PF00179.21 EEQ33935.1 - 3.7e-50 168.9 0.0 4.2e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TP6A_N PF04406.9 EEQ33936.1 - 7e-14 51.2 0.0 1.2e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Methyltransf_23 PF13489.1 EEQ33937.1 - 2.8e-12 46.6 0.0 1.5e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ33937.1 - 1.7e-08 35.0 0.0 6.2e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ33937.1 - 9.5e-06 25.2 0.0 5.5e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ33937.1 - 0.00032 21.1 0.0 0.005 17.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ33937.1 - 0.0065 15.5 0.0 0.017 14.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EEQ33937.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 EEQ33937.1 - 0.029 14.8 0.0 0.09 13.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EEQ33937.1 - 0.031 13.6 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain DUF938 PF06080.7 EEQ33937.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) NADHdh-2_N PF12155.3 EEQ33937.1 - 0.077 13.1 0.5 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal DUF2263 PF10021.4 EEQ33939.1 - 2.6e-23 82.6 0.0 5.2e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Pept_tRNA_hydro PF01195.14 EEQ33940.1 - 6.2e-25 87.7 0.1 5.2e-11 42.3 0.0 3.0 2 1 0 2 2 2 2 Peptidyl-tRNA hydrolase Pkinase PF00069.20 EEQ33941.1 - 6.2e-58 195.9 0.0 1.2e-57 195.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33941.1 - 2.5e-34 118.5 0.0 3e-32 111.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ33941.1 - 1.8e-09 36.9 0.0 2.8e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEQ33941.1 - 0.005 16.6 0.1 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.7 EEQ33942.1 - 2.3e-24 85.7 0.0 3.1e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EEQ33942.1 - 0.0017 18.1 1.0 0.0043 16.9 0.6 1.7 1 1 1 2 2 2 1 Sedlin, N-terminal conserved region Longin PF13774.1 EEQ33942.1 - 0.086 12.4 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Regulated-SNARE-like domain Pkinase PF00069.20 EEQ33943.1 - 1.3e-63 214.6 0.0 2e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33943.1 - 2.2e-26 92.5 0.0 3.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ33943.1 - 0.012 14.6 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ33943.1 - 0.015 14.2 0.0 0.054 12.4 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Macoilin PF09726.4 EEQ33943.1 - 4 5.6 11.6 6.3 4.9 8.0 1.3 1 0 0 1 1 1 0 Transmembrane protein BAR PF03114.13 EEQ33944.1 - 5.6e-63 212.5 4.4 7.2e-63 212.1 3.1 1.1 1 0 0 1 1 1 1 BAR domain HrpB2 PF09487.5 EEQ33944.1 - 0.078 13.1 1.8 0.12 12.5 0.2 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) FliD_N PF02465.13 EEQ33944.1 - 0.46 10.8 3.0 19 5.7 0.3 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SET PF00856.23 EEQ33947.1 - 9.9e-22 77.9 0.3 9.9e-22 77.9 0.2 3.5 3 2 0 3 3 3 1 SET domain SRI PF08236.6 EEQ33947.1 - 2.7e-20 72.0 15.2 3.2e-20 71.8 9.2 2.1 1 1 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain DUF3287 PF11690.3 EEQ33947.1 - 0.0065 16.5 4.6 0.0084 16.1 1.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3287) Med26 PF08711.6 EEQ33947.1 - 0.016 14.7 0.1 0.042 13.3 0.1 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Brix PF04427.13 EEQ33949.1 - 9e-38 129.8 0.3 1.5e-37 129.1 0.2 1.3 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 EEQ33949.1 - 2.3 6.0 17.8 3.1 5.5 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_2b PF00587.20 EEQ33950.1 - 8.8e-67 224.0 0.0 1.4e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ33950.1 - 3.1e-19 68.6 0.0 3.1e-19 68.6 0.0 2.7 3 0 0 3 3 3 1 Anticodon binding domain Pkinase PF00069.20 EEQ33952.1 - 1.8e-64 217.4 0.0 3.7e-64 216.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ33952.1 - 3e-48 164.1 0.1 6.6e-48 163.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EEQ33952.1 - 9.8e-24 83.5 0.3 1.2e-22 80.0 0.0 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 EEQ33952.1 - 1.6e-23 83.0 0.7 3.5e-23 81.9 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EEQ33952.1 - 2.3e-07 30.9 0.0 4.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EEQ33952.1 - 8.4e-06 24.9 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EEQ33952.1 - 0.033 13.0 0.1 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EEQ33952.1 - 0.46 10.1 4.9 0.11 12.2 0.2 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family NAD_kinase PF01513.16 EEQ33953.1 - 2.7e-48 164.2 0.0 3.7e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 EEQ33954.1 - 5.5e-26 90.5 0.0 1.3e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase TPR_2 PF07719.12 EEQ33954.1 - 2.8e-23 79.9 17.3 0.0065 16.3 0.1 11.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ33954.1 - 6e-22 77.7 20.2 9.6e-06 25.8 0.1 8.2 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ33954.1 - 1.4e-21 75.8 35.3 2.3e-06 27.1 0.0 11.6 6 2 5 13 13 13 6 TPR repeat TPR_1 PF00515.23 EEQ33954.1 - 3.8e-21 73.7 18.8 0.0011 18.4 0.1 11.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ33954.1 - 4.1e-15 54.3 17.2 0.09 12.6 0.0 10.9 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ33954.1 - 6.5e-15 54.8 24.7 9e-06 25.5 0.7 10.1 9 1 2 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ33954.1 - 2.9e-13 49.1 26.7 0.0066 16.9 0.0 11.6 8 2 2 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ33954.1 - 1e-12 48.3 37.2 0.00041 20.9 0.0 10.3 11 1 0 11 11 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EEQ33954.1 - 8.2e-06 25.8 15.1 0.84 9.8 0.0 7.2 6 2 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EEQ33954.1 - 2.6e-05 24.3 23.6 0.064 13.7 0.0 10.7 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ33954.1 - 9.8e-05 21.8 17.1 2.3 8.2 0.0 9.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ33954.1 - 0.00048 20.1 25.5 0.18 12.0 0.0 10.5 12 1 1 13 13 11 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ33954.1 - 0.31 11.0 16.9 0.069 13.1 0.2 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat SGL PF08450.7 EEQ33955.1 - 1.2e-27 96.8 1.0 3.5e-25 88.8 0.7 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EEQ33955.1 - 0.00012 22.0 0.0 0.0042 17.0 0.0 3.2 3 1 0 3 3 3 1 Strictosidine synthase Arylesterase PF01731.15 EEQ33955.1 - 0.068 13.1 0.1 0.61 10.1 0.0 2.5 3 0 0 3 3 3 0 Arylesterase Zn_clus PF00172.13 EEQ33956.1 - 0.061 13.2 3.1 0.12 12.3 2.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Es2 PF09751.4 EEQ33960.1 - 2.2e-108 363.3 4.1 2.6e-108 363.1 2.8 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 Anophelin PF10731.4 EEQ33960.1 - 0.11 12.6 1.4 0.27 11.3 1.0 1.7 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito RE_LlaMI PF09562.5 EEQ33960.1 - 0.11 11.6 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 LlaMI restriction endonuclease Mid1 PF12929.2 EEQ33961.1 - 6.8e-151 502.8 6.1 7.9e-151 502.5 4.2 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EEQ33961.1 - 1.2 9.5 6.6 4.9 7.5 2.3 2.5 2 1 0 2 2 2 0 Fz domain CorA PF01544.13 EEQ33962.1 - 5.8e-42 143.7 0.0 8.1e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein YqcI_YcgG PF08892.6 EEQ33963.1 - 5.4e-60 202.6 0.1 6.8e-60 202.3 0.1 1.1 1 0 0 1 1 1 1 YqcI/YcgG family MFS_1 PF07690.11 EEQ33964.1 - 2.9e-30 105.1 38.6 2.9e-30 105.1 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ33964.1 - 2.2e-13 49.6 7.3 2.2e-13 49.6 5.1 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EEQ33964.1 - 0.47 8.5 13.8 0.0069 14.6 4.2 1.8 3 0 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) SPC12 PF06645.8 EEQ33965.1 - 1.1e-17 63.6 2.9 1.7e-16 59.8 2.0 2.0 1 1 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF486 PF04342.7 EEQ33965.1 - 0.051 13.6 0.0 0.061 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF486 zf-rbx1 PF12678.2 EEQ33966.1 - 4.9e-35 119.4 12.9 6.1e-35 119.1 8.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEQ33966.1 - 5.2e-17 61.4 9.8 6.8e-17 61.0 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EEQ33966.1 - 2.7e-07 30.3 12.6 1.6e-06 27.8 8.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ33966.1 - 0.0021 17.6 11.7 0.037 13.6 8.1 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ33966.1 - 0.0042 16.7 9.6 0.32 10.6 6.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ33966.1 - 0.046 13.7 8.4 0.046 13.7 5.8 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EEQ33966.1 - 0.089 12.7 8.8 0.44 10.5 6.2 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EEQ33966.1 - 0.7 9.9 9.3 1.5 8.8 6.4 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEQ33966.1 - 1.2 9.2 10.3 53 4.0 7.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EEQ33966.1 - 1.6 8.5 6.4 38 4.0 4.4 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EEQ33966.1 - 2.7 7.7 11.9 19 5.0 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain PNRC PF15365.1 EEQ33967.1 - 1.7e-07 31.0 2.3 1.7e-07 31.0 1.6 3.7 3 1 0 3 3 3 2 Proline-rich nuclear receptor coactivator SMI1_KNR4 PF09346.5 EEQ33968.1 - 1.1e-34 119.2 0.0 1.6e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DUF4160 PF13711.1 EEQ33968.1 - 0.098 12.5 0.3 19 5.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Thioredoxin PF00085.15 EEQ33969.1 - 0.00019 21.0 0.0 0.0005 19.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Peptidase_M14 PF00246.19 EEQ33970.1 - 2.6e-72 243.7 0.0 5.1e-72 242.8 0.0 1.4 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EEQ33970.1 - 1.6e-08 34.0 0.0 5e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase activation peptide AstE_AspA PF04952.9 EEQ33970.1 - 0.1 11.4 0.1 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Methyltransf_25 PF13649.1 EEQ33971.1 - 7.7e-11 42.2 0.0 1.6e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ33971.1 - 1.7e-05 25.3 0.0 4.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ33971.1 - 2.4e-05 24.0 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ33971.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ33971.1 - 0.0049 16.4 0.0 0.008 15.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ33971.1 - 0.013 16.0 0.0 0.046 14.1 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ33971.1 - 0.026 13.9 0.0 0.077 12.4 0.0 1.8 1 1 0 1 1 1 0 Putative methyltransferase FSH1 PF03959.8 EEQ33972.1 - 3.5e-30 105.0 0.0 4.8e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EEQ33972.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ33972.1 - 0.0014 18.5 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEQ33972.1 - 0.0034 16.8 0.2 2 7.7 0.2 2.6 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase DRY_EERY PF09750.4 EEQ33972.1 - 0.053 13.6 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Alternative splicing regulator Syntaxin-6_N PF09177.6 EEQ33973.1 - 0.0025 18.1 1.4 0.0025 18.1 0.9 7.5 3 3 5 8 8 8 1 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.7 EEQ33973.1 - 0.008 16.0 39.8 0.16 11.7 2.8 6.5 2 1 6 8 8 8 3 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_C_2 PF01322.15 EEQ33973.1 - 0.018 15.5 1.9 0.018 15.5 1.3 4.3 4 2 1 5 5 5 0 Cytochrome C' Filament PF00038.16 EEQ33973.1 - 0.062 12.7 45.1 0.2 11.0 10.9 4.9 1 1 2 3 3 3 0 Intermediate filament protein DUF1342 PF07072.6 EEQ33973.1 - 0.16 11.5 7.8 0.11 12.0 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1342) KxDL PF10241.4 EEQ33973.1 - 3.5 7.5 25.5 2.8 7.9 1.0 5.8 5 1 1 6 6 6 0 Uncharacterized conserved protein GrpE PF01025.14 EEQ33973.1 - 6.3 6.3 27.7 0.044 13.3 4.1 4.5 2 1 2 4 4 4 0 GrpE TIP49 PF06068.8 EEQ33974.1 - 1.4e-173 577.2 2.6 1.6e-173 576.9 1.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EEQ33974.1 - 3.2e-08 33.8 0.3 3.4e-05 24.0 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEQ33974.1 - 9e-07 28.1 1.5 0.00024 20.2 0.0 2.5 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EEQ33974.1 - 3e-06 26.3 0.4 4.6e-06 25.6 0.3 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EEQ33974.1 - 0.00015 21.8 0.0 0.00097 19.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ33974.1 - 0.0003 20.9 0.0 0.31 11.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EEQ33974.1 - 0.0011 18.1 1.0 0.015 14.4 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ33974.1 - 0.0069 16.1 0.2 0.86 9.3 0.0 3.0 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEQ33974.1 - 0.0079 16.0 0.0 4.4 7.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EEQ33974.1 - 0.029 14.1 0.7 0.081 12.6 0.3 1.8 1 1 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EEQ33974.1 - 0.029 13.7 0.1 0.055 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEQ33974.1 - 0.029 13.8 0.0 8.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EEQ33974.1 - 0.076 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 EEQ33974.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain GYF PF02213.11 EEQ33975.1 - 1.6e-08 33.9 0.5 3.2e-08 33.0 0.3 1.5 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.9 EEQ33976.1 - 2.2e-75 251.6 0.0 2.9e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EEQ33976.1 - 0.063 12.9 0.0 0.45 10.1 0.0 2.1 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 DUF829 PF05705.9 EEQ33977.1 - 2.8e-52 177.7 0.0 3.3e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF1477 PF07346.6 EEQ33981.1 - 0.097 12.7 0.3 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) Syndecan PF01034.15 EEQ33981.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Pex14_N PF04695.8 EEQ33981.1 - 5.8 6.9 12.4 95 3.0 8.6 2.2 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.12 EEQ33981.1 - 8 6.2 23.5 13 5.5 16.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 EEQ33981.1 - 8 4.6 10.4 10 4.2 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Inhibitor_Mig-6 PF11555.3 EEQ33982.1 - 0.11 12.8 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Presenilin PF01080.12 EEQ33982.1 - 0.23 10.2 0.8 0.26 10.0 0.5 1.0 1 0 0 1 1 1 0 Presenilin ORC6 PF05460.8 EEQ33985.1 - 0.0034 16.5 4.9 0.0042 16.2 3.4 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Abp2 PF09441.5 EEQ33986.1 - 1.1e-80 269.7 0.1 1.7e-80 269.0 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 LRR_6 PF13516.1 EEQ33987.1 - 0.7 10.1 3.6 8.9 6.7 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat DUF1675 PF07897.6 EEQ33987.1 - 2.7 7.8 9.4 0.11 12.4 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) WW PF00397.21 EEQ33988.1 - 3.4e-07 30.0 2.7 7.4e-07 28.9 1.9 1.6 1 0 0 1 1 1 1 WW domain Brix PF04427.13 EEQ33989.1 - 6.4e-32 110.7 0.0 9.3e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain CDC45 PF02724.9 EEQ33989.1 - 0.043 11.8 3.7 0.079 10.9 2.6 1.5 1 0 0 1 1 1 0 CDC45-like protein DUF2551 PF10826.3 EEQ33989.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) DUF1356 PF07092.7 EEQ33989.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Nop14 PF04147.7 EEQ33989.1 - 0.096 10.5 9.2 0.16 9.8 6.4 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 EEQ33989.1 - 5 5.1 5.2 7.7 4.4 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 F-box-like PF12937.2 EEQ33990.1 - 1.8e-07 30.7 0.7 8e-07 28.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEQ33990.1 - 0.0016 18.0 0.2 0.0054 16.3 0.1 1.9 1 0 0 1 1 1 1 F-box domain Ribosomal_L14e PF01929.12 EEQ33990.1 - 0.0075 16.6 0.1 0.027 14.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L14 DUF1838 PF08894.6 EEQ33990.1 - 0.014 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) Ras PF00071.17 EEQ33991.1 - 3.8e-62 208.4 0.2 4.6e-62 208.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ33991.1 - 3.2e-21 76.0 0.1 5.9e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ33991.1 - 7.7e-13 48.0 0.1 1e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEQ33991.1 - 5.4e-08 32.8 0.1 9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEQ33991.1 - 2.2e-05 24.5 0.1 8.6e-05 22.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EEQ33991.1 - 4.2e-05 23.0 0.1 0.00019 20.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEQ33991.1 - 0.00043 19.4 0.2 0.00076 18.6 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EEQ33991.1 - 0.0011 18.9 0.1 0.0035 17.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EEQ33991.1 - 0.0011 18.1 0.0 0.0013 17.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EEQ33991.1 - 0.0019 17.4 0.1 0.0045 16.1 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EEQ33991.1 - 0.0035 16.5 0.0 0.0045 16.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit SpoIIID PF12116.3 EEQ33991.1 - 0.0041 17.0 0.1 0.057 13.3 0.0 2.2 2 0 0 2 2 2 1 Stage III sporulation protein D AAA_16 PF13191.1 EEQ33991.1 - 0.0075 16.2 0.4 0.018 15.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EEQ33991.1 - 0.0079 16.4 0.1 0.01 16.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 EEQ33991.1 - 0.064 12.8 0.1 0.16 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEQ33991.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EEQ33991.1 - 0.1 11.8 0.1 0.42 9.8 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 EEQ33991.1 - 0.14 12.1 1.4 0.21 11.4 1.0 1.6 1 1 0 1 1 1 0 AAA domain Chromo PF00385.19 EEQ33992.1 - 1.9e-09 37.0 0.2 4.9e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EEQ33992.1 - 0.0042 16.9 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 AAA_2 PF07724.9 EEQ33993.1 - 2.1e-38 131.9 0.0 1.6e-37 129.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EEQ33993.1 - 1e-14 54.8 0.0 2.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EEQ33993.1 - 1.5e-09 37.5 0.1 4.9e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EEQ33993.1 - 1.5e-06 27.9 0.0 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EEQ33993.1 - 0.00013 21.2 0.1 0.0061 15.7 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EEQ33993.1 - 0.00023 20.6 0.0 0.084 12.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 EEQ33993.1 - 0.00057 20.0 0.3 0.0081 16.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ33993.1 - 0.00079 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EEQ33993.1 - 0.0008 20.2 0.1 0.0024 18.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EEQ33993.1 - 0.0011 19.0 0.6 0.003 17.5 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EEQ33993.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EEQ33993.1 - 0.0034 16.9 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ33993.1 - 0.0069 15.4 0.1 0.1 11.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EEQ33993.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EEQ33993.1 - 0.024 13.4 0.2 0.081 11.7 0.1 1.7 1 1 0 1 1 1 0 MCM2/3/5 family AAA_33 PF13671.1 EEQ33993.1 - 0.037 13.9 0.3 0.38 10.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 EEQ33993.1 - 0.047 13.8 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EEQ33993.1 - 0.053 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.6 EEQ33993.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EEQ33993.1 - 0.087 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EEQ33993.1 - 0.1 12.2 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EEQ33993.1 - 0.12 12.6 0.1 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.18 EEQ33996.1 - 2.3e-17 62.7 0.4 4.2e-17 61.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ33996.1 - 2.6e-10 40.0 0.1 6.7e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like ATP-synt_ab PF00006.20 EEQ33997.1 - 5.3e-62 209.1 0.0 8.5e-62 208.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEQ33997.1 - 4e-26 91.7 0.6 7.8e-26 90.7 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEQ33997.1 - 2.2e-22 79.0 2.7 7.2e-22 77.3 1.5 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EEQ33997.1 - 0.00082 18.8 0.1 0.02 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEQ33997.1 - 0.0064 16.7 0.0 0.48 10.6 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EEQ33997.1 - 0.0099 15.6 0.0 0.024 14.3 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 EEQ33997.1 - 0.017 14.3 0.1 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EEQ33997.1 - 0.018 14.7 0.2 1.3 8.7 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EEQ33997.1 - 0.024 14.2 0.1 0.072 12.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 EEQ33997.1 - 0.025 13.6 0.1 0.044 12.8 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 EEQ33997.1 - 0.03 14.3 0.3 0.3 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EEQ33997.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EEQ33997.1 - 0.082 13.0 0.1 0.35 11.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEQ33997.1 - 0.25 10.1 0.6 0.62 8.8 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 EEQ33998.1 - 1.2e-24 86.2 0.0 2.6e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EEQ33998.1 - 1.4e-19 70.6 0.0 4.9e-14 52.4 0.1 2.5 1 1 0 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EEQ33998.1 - 1.6e-16 60.1 0.1 3.9e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) COX4 PF02936.9 EEQ33999.1 - 5.9e-48 162.2 0.3 7.4e-48 161.9 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Cofilin_ADF PF00241.15 EEQ34000.1 - 2.7e-23 82.2 0.0 3.3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.19 EEQ34001.1 - 5.7e-117 391.3 7.0 6.5e-117 391.1 4.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Myb_DNA-binding PF00249.26 EEQ34002.1 - 0.024 14.6 0.1 0.066 13.2 0.1 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain ATP-synt_Eps PF04627.8 EEQ34003.1 - 2.1e-21 75.1 0.5 2.9e-21 74.7 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 EEQ34004.1 - 5e-48 162.4 0.0 1.4e-47 161.0 0.0 1.8 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase SpecificRecomb PF10136.4 EEQ34004.1 - 0.0003 19.0 0.2 0.00041 18.5 0.1 1.1 1 0 0 1 1 1 1 Site-specific recombinase TPD PF14811.1 EEQ34004.1 - 0.071 12.6 0.1 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif ORC5_C PF14630.1 EEQ34005.1 - 6.6e-80 268.4 0.0 8.7e-80 268.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EEQ34005.1 - 1.7e-15 57.4 0.1 1.2e-14 54.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ34005.1 - 5.5e-05 23.3 0.0 0.00014 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ34005.1 - 0.00035 20.1 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family NACHT PF05729.7 EEQ34005.1 - 0.00037 20.1 0.0 0.078 12.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EEQ34005.1 - 0.0039 17.0 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EEQ34005.1 - 0.0047 17.2 0.0 0.0075 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ34005.1 - 0.0047 17.7 0.0 0.0088 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ34005.1 - 0.0062 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 EEQ34005.1 - 0.007 15.8 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KAP_NTPase PF07693.9 EEQ34005.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain T2SE PF00437.15 EEQ34005.1 - 0.012 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EEQ34005.1 - 0.015 15.5 0.0 0.09 12.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EEQ34005.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EEQ34005.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EEQ34005.1 - 0.025 14.8 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EEQ34005.1 - 0.027 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEQ34005.1 - 0.037 14.3 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EEQ34005.1 - 0.043 13.5 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 EEQ34005.1 - 0.053 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EEQ34005.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EEQ34005.1 - 0.094 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 EEQ34005.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EEQ34005.1 - 0.22 10.4 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) VirE PF05272.6 EEQ34005.1 - 0.25 10.8 0.0 1 8.7 0.0 1.8 2 0 0 2 2 2 0 Virulence-associated protein E PUF PF00806.14 EEQ34006.1 - 2.1e-55 181.1 9.6 1.5e-07 30.5 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat RNA_pol_Rpb2_6 PF00562.23 EEQ34008.1 - 3.1e-119 398.1 0.0 5.1e-119 397.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEQ34008.1 - 1.1e-56 191.0 0.4 4.7e-56 188.9 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EEQ34008.1 - 1.8e-29 102.5 1.7 4.8e-29 101.1 1.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EEQ34008.1 - 8e-27 93.3 0.2 2.1e-26 92.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EEQ34008.1 - 1.6e-21 75.8 0.4 6.7e-21 73.8 0.3 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EEQ34008.1 - 1.7e-18 66.1 0.0 4.1e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EEQ34008.1 - 7.6e-13 48.2 0.1 2.6e-12 46.5 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EEQ34008.1 - 0.12 10.6 1.8 0.12 10.7 0.1 1.7 2 0 0 2 2 2 0 Baculovirus Y142 protein DUF3632 PF12311.3 EEQ34009.1 - 1.2e-38 132.8 3.9 2.3e-38 131.8 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.15 EEQ34010.1 - 2.6e-06 27.4 0.1 3.2e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 ribonuclease DUF1757 PF08560.5 EEQ34010.1 - 0.062 12.9 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) Glycos_transf_1 PF00534.15 EEQ34013.1 - 1.7e-19 69.9 0.0 3.4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEQ34013.1 - 3.2e-10 40.2 0.0 1.6e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EEQ34013.1 - 0.00032 20.8 0.0 0.00075 19.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 E1-E2_ATPase PF00122.15 EEQ34014.1 - 1.5e-42 145.1 5.0 1.5e-42 145.1 3.5 2.8 3 1 1 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.21 EEQ34014.1 - 7e-23 82.1 0.0 2.2e-22 80.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ34014.1 - 2.3e-12 47.5 0.0 5.3e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ34014.1 - 4.6e-12 45.2 0.0 1.1e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EEQ34014.1 - 0.0022 17.9 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ34014.1 - 0.0029 17.2 0.1 0.0029 17.2 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRM_5 PF13893.1 EEQ34017.1 - 2.3e-07 30.5 0.0 4.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ34017.1 - 7.3e-07 28.7 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ34017.1 - 4.2e-05 23.4 0.0 9.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 EEQ34017.1 - 8.2 4.5 28.5 12 3.9 19.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Citrate_synt PF00285.16 EEQ34018.1 - 1.3e-100 336.6 0.0 1.6e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EEQ34018.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.22 EEQ34020.1 - 2.1e-25 88.2 6.8 5.8e-11 41.9 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M16 PF00675.15 EEQ34021.1 - 2.1e-19 69.7 0.0 4.3e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEQ34021.1 - 8e-15 54.9 0.0 1.5e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain UPF0253 PF06786.7 EEQ34021.1 - 2.3 8.3 5.5 0.4 10.8 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) RNA_pol_Rpc82 PF05645.8 EEQ34022.1 - 3.8e-39 134.7 0.0 7.2e-35 120.7 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EEQ34022.1 - 2e-16 59.5 4.3 9.1e-10 38.2 0.2 4.0 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EEQ34022.1 - 1.8e-07 30.5 0.1 1.6e-06 27.5 0.1 2.4 2 0 0 2 2 2 1 TFIIE alpha subunit PBP1_TM PF14812.1 EEQ34022.1 - 0.042 14.1 4.7 1.5 9.1 0.4 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TrmB PF01978.14 EEQ34022.1 - 0.064 12.9 0.1 1.7 8.3 0.0 3.0 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Sec8_exocyst PF04048.9 EEQ34023.1 - 4.1e-25 88.0 6.1 4.1e-18 65.3 0.0 3.3 4 0 0 4 4 4 2 Sec8 exocyst complex component specific domain Fungal_trans_2 PF11951.3 EEQ34024.1 - 6e-06 25.0 1.4 9.8e-06 24.4 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tannase PF07519.6 EEQ34025.1 - 1.4e-98 330.6 0.0 2e-98 330.1 0.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EEQ34025.1 - 0.00076 18.7 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEQ34025.1 - 0.0022 17.9 0.0 0.0043 16.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ34025.1 - 0.082 12.6 0.1 8.4 6.1 0.0 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 EEQ34026.1 - 2.4e-42 144.7 0.0 2.9e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Init_tRNA_PT PF04179.7 EEQ34027.1 - 6e-134 447.2 0.0 2.2e-78 264.1 0.0 2.0 1 1 1 2 2 2 2 Initiator tRNA phosphoribosyl transferase HAD_2 PF13419.1 EEQ34028.1 - 1.1e-15 58.2 0.0 1.4e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ34028.1 - 2.5e-07 30.3 0.0 4.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EEQ34028.1 - 8.3e-06 25.5 0.0 0.00045 19.9 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.21 EEQ34028.1 - 9.9e-05 22.8 0.0 0.0022 18.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NUDIX PF00293.23 EEQ34029.1 - 1.3e-16 60.4 0.0 2.3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Cnd1_N PF12922.2 EEQ34029.1 - 0.045 13.3 0.2 0.066 12.8 0.1 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term NUDIX PF00293.23 EEQ34030.1 - 4e-08 32.9 0.0 1.5e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain Bacteroid_pep PF14406.1 EEQ34031.1 - 0.48 10.6 2.6 1.3 9.2 1.8 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes EST1_DNA_bind PF10373.4 EEQ34032.1 - 1.6e-12 47.2 0.2 4.9e-12 45.6 0.1 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain TFIIB PF00382.14 EEQ34033.1 - 0.0048 16.6 0.0 0.54 10.1 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat FtsQ PF03799.10 EEQ34033.1 - 0.043 14.0 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Cell division protein FtsQ Autophagy_N PF03986.8 EEQ34034.1 - 1.9e-46 157.4 0.1 1.9e-46 157.4 0.0 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EEQ34034.1 - 1.2e-21 76.6 0.3 2.9e-21 75.4 0.2 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EEQ34034.1 - 2.1e-14 52.2 0.5 3.5e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal BUD22 PF09073.5 EEQ34034.1 - 0.021 13.9 11.7 0.075 12.0 0.6 2.0 2 0 0 2 2 2 0 BUD22 Nop25 PF09805.4 EEQ34034.1 - 0.19 11.8 6.3 0.37 10.8 1.1 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Fez1 PF06818.10 EEQ34035.1 - 0.0029 17.6 0.1 0.0046 16.9 0.1 1.2 1 0 0 1 1 1 1 Fez1 Dicty_CAR PF05462.6 EEQ34036.1 - 0.0002 20.3 3.1 0.0002 20.3 2.2 3.0 2 1 1 3 3 3 2 Slime mold cyclic AMP receptor Git3 PF11710.3 EEQ34036.1 - 0.0044 16.6 4.1 0.0044 16.6 2.9 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EEQ34036.1 - 0.0068 16.1 0.6 0.024 14.3 0.4 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Rab5ip PF07019.7 EEQ34036.1 - 2.1 8.5 10.2 7.3 6.8 0.0 3.6 4 0 0 4 4 4 0 Rab5-interacting protein (Rab5ip) Glycos_transf_2 PF00535.21 EEQ34037.1 - 1.5e-21 76.8 0.1 8.8e-11 41.7 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEQ34037.1 - 1.9e-06 27.8 0.0 0.18 11.5 0.0 3.4 1 1 1 2 2 2 2 Glycosyltransferase like family 2 IncA PF04156.9 EEQ34038.1 - 0.021 14.3 8.6 0.013 15.1 3.4 2.2 3 0 0 3 3 3 0 IncA protein Sec8_exocyst PF04048.9 EEQ34038.1 - 0.05 13.2 0.9 0.13 11.8 0.6 1.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain SPX PF03105.14 EEQ34038.1 - 0.088 12.5 6.1 0.82 9.3 4.2 2.2 1 1 0 1 1 1 0 SPX domain SpoIIID PF12116.3 EEQ34038.1 - 0.13 12.1 0.5 0.3 11.0 0.3 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D Cauli_AT PF03233.8 EEQ34038.1 - 0.27 10.9 2.7 0.36 10.5 0.9 1.9 2 0 0 2 2 2 0 Aphid transmission protein DUF2570 PF10828.3 EEQ34038.1 - 0.31 10.6 3.7 1 8.9 2.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Fib_alpha PF08702.5 EEQ34038.1 - 1.5 8.9 4.6 5.5 7.1 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.7 EEQ34038.1 - 3.9 7.4 11.7 4.5 7.3 0.1 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Striatin PF08232.7 EEQ34038.1 - 6.8 7.0 10.6 0.29 11.4 1.7 2.7 3 0 0 3 3 3 0 Striatin family Swi5 PF07061.6 EEQ34039.1 - 3.1e-25 87.7 0.3 4e-25 87.4 0.2 1.1 1 0 0 1 1 1 1 Swi5 DUF1366 PF07104.6 EEQ34039.1 - 0.013 15.0 0.2 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Tropomyosin_1 PF12718.2 EEQ34039.1 - 0.025 14.4 0.1 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Tropomyosin like Prefoldin_2 PF01920.15 EEQ34039.1 - 0.031 14.0 0.9 0.054 13.2 0.6 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF641 PF04859.7 EEQ34039.1 - 0.044 13.5 0.1 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DASH_Spc34 PF08657.5 EEQ34039.1 - 0.055 13.1 0.3 0.07 12.7 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 TBPIP PF07106.8 EEQ34039.1 - 0.066 12.7 0.4 0.081 12.4 0.3 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF603 PF04645.7 EEQ34039.1 - 0.083 12.8 0.9 0.11 12.3 0.7 1.2 1 1 0 1 1 1 0 Protein of unknown function, DUF603 Borrelia_REV PF03978.8 EEQ34039.1 - 0.091 12.4 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Atg14 PF10186.4 EEQ34039.1 - 0.12 11.2 0.2 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 EEQ34039.1 - 0.13 12.1 0.5 0.5 10.2 0.3 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 EEQ34039.1 - 0.32 10.5 2.2 2.4 7.7 1.3 2.0 1 1 1 2 2 2 0 Septum formation initiator Ytp1 PF10355.4 EEQ34040.1 - 6.6e-85 284.5 14.3 6.6e-85 284.5 9.9 1.5 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EEQ34040.1 - 2.3e-31 107.5 4.3 2.3e-31 107.5 3.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3815 PF12821.2 EEQ34040.1 - 0.037 13.9 0.1 0.037 13.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3815) DUF973 PF06157.6 EEQ34040.1 - 4.9 6.0 12.0 0.16 10.9 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF973) PIRT PF15099.1 EEQ34040.1 - 8.4 5.6 7.0 2.5 7.3 0.1 3.0 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family ThiF PF00899.16 EEQ34041.1 - 9.2e-20 70.8 0.0 1.5e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family MFS_1 PF07690.11 EEQ34043.1 - 9e-35 120.0 24.5 1.3e-34 119.5 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 EEQ34043.1 - 0.31 9.8 35.3 0.1 11.4 11.6 3.0 2 1 0 2 2 2 0 Acyltransferase family DUF3147 PF11345.3 EEQ34043.1 - 0.88 9.6 7.0 2.5 8.1 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3147) Na_H_Exchanger PF00999.16 EEQ34044.1 - 1e-69 234.9 45.3 1.4e-69 234.4 31.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peroxin-3 PF04882.7 EEQ34045.1 - 2.3e-143 478.0 0.0 2.6e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF1649 PF07855.7 EEQ34046.1 - 1.4e-64 216.6 0.1 1.6e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) DUF2922 PF11148.3 EEQ34046.1 - 0.00044 19.8 0.1 0.00097 18.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2922) TB2_DP1_HVA22 PF03134.14 EEQ34047.1 - 1.1e-25 89.2 6.6 1.5e-25 88.7 4.6 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2207 PF09972.4 EEQ34047.1 - 0.71 8.3 3.4 0.85 8.1 2.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RFX_DNA_binding PF02257.10 EEQ34048.1 - 5.1e-29 100.2 0.2 1.2e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain PIG-X PF08320.7 EEQ34049.1 - 3.2e-67 225.8 0.0 4.7e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 DnaJ PF00226.26 EEQ34050.1 - 4.4e-27 93.5 2.9 7e-27 92.9 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EEQ34050.1 - 1.3e-23 82.6 0.3 2.4e-21 75.3 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain TGS PF02824.16 EEQ34051.1 - 1.2e-19 69.8 0.4 2.4e-19 68.8 0.1 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 EEQ34051.1 - 2.1e-19 69.5 0.1 5.2e-19 68.3 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ34051.1 - 8.8e-13 47.8 0.0 1.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEQ34051.1 - 2.4e-05 24.2 0.4 0.027 14.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EEQ34051.1 - 0.00065 20.1 0.0 0.0015 19.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EEQ34051.1 - 0.028 13.5 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Methyltransf_33 PF10017.4 EEQ34051.1 - 0.033 14.0 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent ArgK PF03308.11 EEQ34051.1 - 0.055 12.2 0.1 0.11 11.1 0.1 1.5 1 0 0 1 1 1 0 ArgK protein TetR_C_8 PF14278.1 EEQ34051.1 - 0.093 13.1 0.1 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region RRM_1 PF00076.17 EEQ34052.1 - 2e-08 33.7 0.0 5.2e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ34052.1 - 3.3e-07 30.0 0.0 9.2e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ34052.1 - 0.0005 19.9 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ34052.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EEQ34052.1 - 0.043 13.4 1.7 0.078 12.6 1.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HGTP_anticodon2 PF12745.2 EEQ34053.1 - 4.1e-84 281.9 0.2 4.1e-84 281.9 0.2 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EEQ34053.1 - 2.8e-63 213.5 0.0 3.5e-35 121.4 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34053.1 - 1.3e-35 122.7 0.0 1.3e-18 66.9 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EEQ34053.1 - 9.8e-18 64.1 0.5 3.5e-17 62.3 0.3 2.1 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EEQ34053.1 - 2.6e-12 46.4 0.7 1e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 EEQ34053.1 - 0.009 15.7 0.0 0.009 15.7 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Cut12 PF11500.3 EEQ34054.1 - 5.8e-44 149.4 17.3 5.8e-44 149.4 12.0 4.6 4 1 2 7 7 7 1 Spindle pole body formation-associated protein Glutaredoxin2_C PF04399.8 EEQ34054.1 - 0.13 11.8 6.5 2.7 7.5 0.2 2.9 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF89 PF01937.14 EEQ34055.1 - 1.7e-133 444.8 0.0 1.9e-133 444.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Metallophos PF00149.23 EEQ34056.1 - 6.8e-36 123.5 0.0 1.1e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EEQ34056.1 - 1.7e-28 98.4 0.3 3.8e-28 97.3 0.2 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EEQ34056.1 - 1e-19 69.9 2.0 2.8e-15 55.7 0.3 2.7 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 EEQ34056.1 - 1.6e-10 40.1 1.6 0.00077 18.9 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ34056.1 - 2.1e-08 33.4 2.3 0.025 14.4 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ34056.1 - 2e-06 27.5 0.1 0.00087 19.1 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ34056.1 - 1.7e-05 25.3 1.0 0.07 13.8 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ34056.1 - 0.00092 19.2 0.7 3.8 7.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ34056.1 - 0.033 14.6 0.4 11 6.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ34056.1 - 0.034 14.4 0.2 1.4 9.3 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ34056.1 - 0.034 14.7 1.3 15 6.5 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ34056.1 - 0.12 12.3 0.2 0.33 10.9 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Spt4 PF06093.8 EEQ34057.1 - 5.4e-33 112.7 0.2 6.6e-33 112.4 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 EEQ34057.1 - 0.056 13.2 0.6 0.15 11.9 0.5 1.8 1 1 0 1 1 1 0 Coronavirus gene 5 protein Aminotran_3 PF00202.16 EEQ34058.1 - 2.3e-102 342.3 0.0 2.8e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEQ34058.1 - 0.039 12.9 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II AMP-binding PF00501.23 EEQ34059.1 - 1.9e-30 105.5 0.0 9.2e-29 100.0 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 EEQ34059.1 - 4.9e-30 104.2 0.0 4.1e-29 101.2 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EEQ34059.1 - 1.4e-06 28.4 0.0 3.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EEQ34059.1 - 2.9e-05 23.6 0.0 5.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 EEQ34060.1 - 1.6e-35 122.6 0.0 2.8e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ34060.1 - 0.00015 21.0 0.0 0.44 9.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 EEQ34060.1 - 0.00068 18.9 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEQ34060.1 - 0.093 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family GMC_oxred_C PF05199.8 EEQ34061.1 - 8.6e-19 68.2 0.0 1.3e-17 64.3 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase Zn_clus PF00172.13 EEQ34061.1 - 1.4e-07 31.2 10.7 3.3e-07 30.0 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ34061.1 - 8.7e-05 21.5 0.5 0.00016 20.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bestrophin PF01062.16 EEQ34062.1 - 5.2e-47 160.2 0.0 4.3e-46 157.1 0.0 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel GSH_synth_ATP PF03917.12 EEQ34066.1 - 3.7e-96 321.9 0.0 4.6e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EEQ34066.1 - 5.3e-28 97.1 0.0 8.2e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 EEQ34067.1 - 3.9e-51 173.6 0.1 7.8e-51 172.6 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ34067.1 - 1.5e-12 47.1 0.0 3.4e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ34067.1 - 1.7e-06 28.0 0.3 8.2e-05 22.5 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SAM_1 PF00536.25 EEQ34067.1 - 0.0087 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EEQ34067.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SNF2_N PF00176.18 EEQ34068.1 - 2.8e-70 236.4 0.0 4.2e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EEQ34068.1 - 3.1e-14 52.8 0.0 6.7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EEQ34068.1 - 5.9e-11 42.0 0.0 2.2e-10 40.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EEQ34068.1 - 1.4e-10 40.8 7.6 3e-10 39.7 4.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ34068.1 - 7e-09 35.5 8.1 7e-09 35.5 5.6 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ34068.1 - 7.7e-08 31.8 8.0 7.7e-08 31.8 5.5 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ34068.1 - 8.6e-07 28.5 8.6 1.9e-06 27.4 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ34068.1 - 2.8e-06 27.3 2.0 8.9e-06 25.7 1.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEQ34068.1 - 2.2e-05 24.0 5.7 5.1e-05 22.9 3.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEQ34068.1 - 0.00014 21.6 9.3 0.00027 20.7 6.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EEQ34068.1 - 0.0012 18.3 7.3 0.0057 16.1 3.3 2.9 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EEQ34068.1 - 0.0073 16.2 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 U-box domain HDA2-3 PF11496.3 EEQ34068.1 - 0.017 13.9 0.1 0.18 10.5 0.1 2.3 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 zf-RING_UBOX PF13445.1 EEQ34068.1 - 0.022 14.4 7.8 0.031 13.9 4.4 2.2 2 0 0 2 2 2 0 RING-type zinc-finger DUF1644 PF07800.7 EEQ34068.1 - 0.14 12.0 2.8 0.41 10.5 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-Apc11 PF12861.2 EEQ34068.1 - 0.18 11.6 1.8 0.58 10.0 1.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MBOAT_2 PF13813.1 EEQ34069.1 - 1.7e-18 66.4 2.6 4.3e-18 65.1 1.8 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family 2TM PF13239.1 EEQ34069.1 - 2 8.5 10.1 6.3 6.9 0.9 3.1 2 0 0 2 2 2 0 2TM domain RIX1 PF08167.7 EEQ34070.1 - 2.3e-59 199.7 1.0 2.3e-59 199.7 0.7 1.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Terminase_6 PF03237.10 EEQ34070.1 - 0.16 10.7 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family TPR_8 PF13181.1 EEQ34071.1 - 1.5e-10 40.0 0.3 3.8e-05 23.1 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ34071.1 - 1.3e-09 37.2 0.5 0.14 12.1 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ34071.1 - 9.6e-09 35.1 11.6 0.16 12.6 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ34071.1 - 2.1e-08 33.6 3.9 0.00092 18.8 0.0 5.0 5 0 0 5 5 5 2 TPR repeat TPR_19 PF14559.1 EEQ34071.1 - 1.5e-07 31.6 4.6 0.064 13.6 0.0 4.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ34071.1 - 5.1e-07 29.3 0.2 0.2 11.9 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ34071.1 - 4.7e-06 27.1 13.5 0.13 12.9 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ34071.1 - 1.6e-05 24.3 1.3 0.011 15.3 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ34071.1 - 0.0069 16.7 2.4 7.8 7.1 0.1 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EEQ34071.1 - 0.06 13.4 0.8 2.8 8.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ34071.1 - 0.47 10.4 5.9 27 4.7 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat NDUFA12 PF05071.11 EEQ34072.1 - 1.5e-27 96.0 2.8 2e-27 95.6 2.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 EEQ34073.1 - 8.1e-15 54.6 0.0 1e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EEQ34073.1 - 5.5e-10 38.7 0.4 0.00034 20.3 0.0 2.9 2 1 0 2 2 2 2 Phospholipase D Active site motif LTV PF04180.9 EEQ34074.1 - 1.1e-69 235.9 13.7 1.5e-69 235.5 9.5 1.2 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 EEQ34075.1 - 1.9e-17 63.2 0.5 6.4e-15 55.1 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ34075.1 - 1.7e-06 27.3 0.3 5e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEQ34075.1 - 0.0005 19.9 1.2 0.22 11.3 0.2 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EEQ34075.1 - 0.0012 18.0 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EEQ34075.1 - 0.0024 17.0 0.1 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RNA_pol_3_Rpc31 PF11705.3 EEQ34075.1 - 0.023 14.6 7.5 0.064 13.1 5.2 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Miro PF08477.8 EEQ34075.1 - 0.068 13.6 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein zf-C2H2_4 PF13894.1 EEQ34076.1 - 3e-05 24.0 12.2 0.062 13.6 0.5 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ34076.1 - 0.029 14.6 10.8 0.063 13.6 0.2 3.7 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EEQ34076.1 - 0.03 14.2 0.2 0.23 11.4 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Fungal_trans PF04082.13 EEQ34077.1 - 7.4e-15 54.5 1.7 4.1e-14 52.0 0.1 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEQ34077.1 - 3.1e-11 42.9 9.7 6.3e-05 23.0 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ34077.1 - 2.9e-08 33.6 4.0 2.9e-08 33.6 2.8 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ34077.1 - 9.7e-07 28.7 14.3 0.0011 19.1 3.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ34077.1 - 0.0064 16.6 1.8 0.28 11.3 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ34077.1 - 0.042 14.0 2.8 0.4 10.9 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EEQ34077.1 - 0.11 12.1 3.8 2.2 8.0 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EEQ34077.1 - 0.33 11.1 3.4 0.81 9.8 2.4 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 EEQ34077.1 - 0.36 10.9 1.8 0.69 10.0 1.2 1.4 1 0 0 1 1 1 0 LIM domain zf-FCS PF06467.9 EEQ34077.1 - 0.36 10.5 1.9 0.79 9.4 1.3 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_6 PF13912.1 EEQ34077.1 - 1.2 9.1 5.2 9.5 6.2 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EEQ34077.1 - 3 7.6 6.3 3.9 7.2 1.1 2.9 2 1 1 3 3 3 0 BED zinc finger Pkinase PF00069.20 EEQ34078.1 - 1.7e-66 224.0 0.0 3.9e-66 222.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34078.1 - 4.3e-48 163.6 0.0 9.4e-48 162.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EEQ34078.1 - 2.4e-31 107.7 0.0 6.3e-31 106.4 0.0 1.8 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EEQ34078.1 - 1.3e-15 57.2 0.0 2.9e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EEQ34078.1 - 5.3e-14 51.8 0.0 1.2e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EEQ34078.1 - 7.1e-08 31.7 0.0 0.00026 20.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 EEQ34078.1 - 0.00029 21.2 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 EEQ34078.1 - 0.031 13.3 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pneumo_M2 PF07380.6 EEQ34078.1 - 0.14 12.1 0.0 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 Pneumovirus M2 protein Seadorna_VP7 PF07387.6 EEQ34078.1 - 0.15 10.9 0.1 0.73 8.6 0.0 2.2 3 0 0 3 3 3 0 Seadornavirus VP7 Ribosomal_L5_C PF00673.16 EEQ34079.1 - 1.2e-23 82.6 0.0 2.1e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus CoA_binding PF02629.14 EEQ34080.1 - 3e-26 91.7 5.1 1e-25 90.0 1.4 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EEQ34080.1 - 2.1e-22 79.3 0.2 3.8e-22 78.5 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EEQ34080.1 - 6.1e-08 32.3 0.1 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EEQ34080.1 - 0.00012 22.1 0.1 0.00027 21.0 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Radical_SAM PF04055.16 EEQ34081.1 - 1.2e-17 64.5 0.0 6.5e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EEQ34081.1 - 3.2e-11 43.1 0.0 7.6e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2463 PF09591.5 EEQ34082.1 - 0.0083 15.7 0.5 0.009 15.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) DUF4064 PF13273.1 EEQ34082.1 - 0.012 15.7 0.6 0.015 15.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) MIG-14_Wnt-bd PF06664.7 EEQ34082.1 - 0.038 12.8 0.9 0.044 12.6 0.6 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF3810 PF12725.2 EEQ34082.1 - 0.062 12.2 1.1 0.07 12.0 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) FtsX PF02687.16 EEQ34082.1 - 0.087 12.5 1.1 0.13 12.0 0.8 1.2 1 0 0 1 1 1 0 FtsX-like permease family DUF4013 PF13197.1 EEQ34082.1 - 0.091 12.0 1.5 0.11 11.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) 5TM-5TMR_LYT PF07694.7 EEQ34082.1 - 0.094 12.0 2.1 0.14 11.4 1.4 1.3 1 1 0 1 1 1 0 5TMR of 5TMR-LYT DUF3112 PF11309.3 EEQ34082.1 - 0.11 12.2 1.6 0.13 12.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) TMEMspv1-c74-12 PF11044.3 EEQ34082.1 - 7.6 6.1 5.8 21 4.7 0.1 2.3 2 1 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein His_biosynth PF00977.16 EEQ34083.1 - 1.7e-30 105.9 0.0 2.1e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Acetone_carb_G PF08882.6 EEQ34083.1 - 0.074 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit Chordopox_A13L PF05961.6 EEQ34083.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Ribul_P_3_epim PF00834.14 EEQ34083.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.1 EEQ34084.1 - 0.0044 17.0 5.8 0.0044 17.0 4.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4602) DNA_pol_phi PF04931.8 EEQ34084.1 - 2.1 6.0 6.4 2.8 5.5 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi STE PF02200.11 EEQ34085.1 - 1.2e-51 173.4 0.1 2.9e-51 172.2 0.0 1.7 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 EEQ34085.1 - 0.00042 20.4 3.2 0.0013 18.9 2.2 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ34085.1 - 0.001 19.2 2.4 0.003 17.7 1.7 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger MFS_2 PF13347.1 EEQ34086.1 - 4.2e-06 25.4 10.9 2.6e-05 22.8 3.6 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.10 EEQ34086.1 - 0.00037 19.3 1.0 0.00066 18.4 0.7 1.3 1 0 0 1 1 1 1 PUCC protein Na_H_Exchanger PF00999.16 EEQ34088.1 - 3.6e-68 229.8 35.8 4.6e-68 229.4 24.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3522 PF12036.3 EEQ34088.1 - 0.95 9.2 10.7 2 8.1 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3522) PepSY_TM_2 PF13703.1 EEQ34088.1 - 1.1 9.5 8.9 0.33 11.1 0.3 3.8 3 1 0 3 3 3 0 PepSY-associated TM helix SNF2_N PF00176.18 EEQ34089.1 - 1.2e-70 237.7 3.9 1.2e-70 237.7 2.7 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EEQ34089.1 - 1.4e-51 174.2 21.8 1.4e-51 174.2 15.1 4.5 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EEQ34089.1 - 8.7e-16 57.5 0.0 2.5e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pep3_Vps18 PF05131.9 EEQ34091.1 - 3.1e-47 159.7 0.0 6.9e-47 158.5 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EEQ34091.1 - 2.4e-10 40.1 1.9 9.4e-06 25.2 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EEQ34091.1 - 0.00047 19.9 0.6 0.001 18.8 0.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ34091.1 - 0.0018 17.9 0.7 0.004 16.8 0.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.4 EEQ34091.1 - 0.03 14.3 0.1 0.099 12.7 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Vps39_2 PF10367.4 EEQ34091.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 EEQ34091.1 - 0.15 11.6 2.3 0.11 12.1 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ34091.1 - 0.29 11.1 1.1 0.67 10.0 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 EEQ34093.1 - 2.6e-49 167.7 0.0 4e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34093.1 - 9.8e-29 100.1 0.0 1.4e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ34093.1 - 1.8e-08 33.6 0.0 1e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Sad1_UNC PF07738.8 EEQ34094.1 - 1.5e-33 115.4 0.0 2.5e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Spo12 PF05032.7 EEQ34095.1 - 7.2e-15 54.3 1.4 1.4e-14 53.3 1.0 1.5 1 0 0 1 1 1 1 Spo12 family IGPD PF00475.13 EEQ34096.1 - 5.5e-60 201.4 1.3 8.1e-60 200.8 0.9 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase MGAT2 PF05060.9 EEQ34096.1 - 0.075 11.9 0.2 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Acyl-CoA_dh_1 PF00441.19 EEQ34097.1 - 1.9e-30 105.9 2.8 1.9e-30 105.9 2.0 1.6 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ34097.1 - 4.6e-16 58.0 0.0 1.1e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEQ34097.1 - 8.7e-16 58.3 4.7 1.7e-15 57.4 3.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ34097.1 - 2.8e-13 50.4 0.4 6.6e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain EST1_DNA_bind PF10373.4 EEQ34098.1 - 1.5e-59 201.5 5.5 2.5e-59 200.8 3.8 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EEQ34098.1 - 7.4e-18 64.7 1.7 1.3e-17 64.0 0.2 2.0 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EEQ34098.1 - 0.048 13.3 0.4 0.15 11.7 0.3 1.9 1 0 0 1 1 1 0 TPR repeat PfkB PF00294.19 EEQ34099.1 - 1.4e-65 221.4 0.0 1.6e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EEQ34099.1 - 1.8e-05 24.0 0.0 3.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PS_pyruv_trans PF04230.8 EEQ34099.1 - 0.0055 16.4 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase DUF1770 PF08589.5 EEQ34100.1 - 1.1e-15 58.0 0.2 1.4e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.1 EEQ34101.1 - 0.0012 18.6 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 EEQ34101.1 - 0.02 14.7 0.2 0.066 13.1 0.1 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Nop14 PF04147.7 EEQ34101.1 - 0.27 9.1 5.3 0.38 8.6 3.7 1.3 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L2_C PF03947.13 EEQ34102.1 - 8e-37 125.9 4.9 8e-37 125.9 3.4 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEQ34102.1 - 1.6e-12 47.1 0.1 3.6e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ada_Zn_binding PF02805.11 EEQ34103.1 - 3.6e-29 100.1 5.4 6.3e-29 99.3 3.7 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EEQ34103.1 - 2.6e-07 30.2 0.0 4.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EEQ34103.1 - 0.0016 18.5 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Pex14_N PF04695.8 EEQ34103.1 - 3.4 7.7 10.8 3.5 7.6 0.2 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAR PF03114.13 EEQ34104.1 - 1e-41 142.9 6.8 1.3e-41 142.6 4.7 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EEQ34104.1 - 4.8e-07 28.9 3.1 5.3e-07 28.8 2.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking FmrO PF07091.6 EEQ34104.1 - 0.012 14.5 2.2 0.22 10.4 0.0 2.1 1 1 1 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) DUF4337 PF14235.1 EEQ34104.1 - 1.1 9.0 6.4 1.8 8.3 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) APG6 PF04111.7 EEQ34104.1 - 2.2 7.2 9.5 3.6 6.5 6.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 MscS_TM PF12794.2 EEQ34104.1 - 2.3 6.7 4.1 3.7 6.0 2.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 HSA PF07529.8 EEQ34105.1 - 1.6e-16 59.8 9.6 1.6e-16 59.8 6.6 2.5 3 0 0 3 3 3 1 HSA QLQ PF08880.6 EEQ34105.1 - 7.8e-12 44.4 4.2 7.8e-12 44.4 2.9 2.8 3 0 0 3 3 3 1 QLQ DUF3518 PF12031.3 EEQ34105.1 - 0.093 11.5 0.2 0.19 10.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) Bromodomain PF00439.20 EEQ34106.1 - 1e-25 89.4 1.0 1.1e-24 86.1 0.5 2.3 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.1 EEQ34106.1 - 1.5e-17 63.5 0.6 1.5e-17 63.5 0.4 3.7 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex DinB PF05163.7 EEQ34106.1 - 2.4 7.8 8.1 2.6 7.7 0.5 3.0 3 0 0 3 3 3 0 DinB family Aminotran_1_2 PF00155.16 EEQ34109.1 - 6.2e-85 285.3 0.0 8e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEQ34109.1 - 1.3e-06 27.0 0.0 2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEQ34109.1 - 4.7e-05 22.5 0.2 8.2e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EEQ34109.1 - 5.7e-05 22.0 0.0 0.00011 21.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEQ34109.1 - 0.0051 15.9 1.0 0.016 14.3 0.4 1.8 1 1 0 2 2 2 1 Beta-eliminating lyase RNA_pol_I_A49 PF06870.7 EEQ34110.1 - 8e-51 172.7 0.0 1.7e-50 171.7 0.0 1.4 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Ribosomal_L41 PF05162.8 EEQ34111.1 - 1.2e-06 28.0 25.8 2.1e-06 27.2 17.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L41 GATase PF00117.23 EEQ34112.1 - 6.4e-46 156.2 0.0 9.9e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EEQ34112.1 - 4.9e-45 152.2 0.0 1.5e-44 150.6 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EEQ34112.1 - 8.9e-06 25.2 0.2 0.00031 20.2 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DUF1250 PF06855.7 EEQ34112.1 - 0.096 12.2 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) MscS_TM PF12794.2 EEQ34113.1 - 0.029 12.9 0.8 0.034 12.7 0.5 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 CMS1 PF14617.1 EEQ34113.1 - 0.13 11.2 0.1 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Peptidase_S10 PF00450.17 EEQ34114.1 - 2.5e-89 300.3 10.0 6.5e-89 298.9 6.9 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_3 PF13302.1 EEQ34115.1 - 1.8e-10 41.0 0.0 2.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ34115.1 - 3.6e-06 26.9 0.0 9.7e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EEQ34115.1 - 0.12 12.3 0.0 0.53 10.2 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PARP PF00644.15 EEQ34116.1 - 8.1e-65 218.0 0.0 8.1e-65 218.0 0.0 2.7 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EEQ34116.1 - 2.5e-42 143.6 0.3 4e-42 143.0 0.2 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EEQ34116.1 - 1.6e-21 76.0 0.1 1.6e-21 76.0 0.1 2.6 3 0 0 3 3 3 1 WGR domain BRCT PF00533.21 EEQ34116.1 - 5.2e-11 42.5 0.0 1.5e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEQ34116.1 - 4.9e-09 35.9 0.1 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF500 PF04366.7 EEQ34117.1 - 3.6e-43 146.0 0.0 6.1e-43 145.2 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) ETF PF01012.16 EEQ34118.1 - 1e-32 113.1 0.5 1.4e-32 112.7 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Flavodoxin_1 PF00258.20 EEQ34119.1 - 1e-31 109.8 0.0 6.2e-31 107.3 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.15 EEQ34119.1 - 1.8e-31 109.2 0.0 2.8e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEQ34119.1 - 1.6e-14 54.3 0.0 2.9e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EEQ34119.1 - 0.0003 20.8 0.0 0.035 14.1 0.0 2.9 2 1 1 3 3 3 1 Flavodoxin domain Flavodoxin_3 PF12641.2 EEQ34119.1 - 0.021 14.2 0.0 0.095 12.1 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain APH PF01636.18 EEQ34120.1 - 0.039 13.6 0.0 8 6.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RNA_pol_3_Rpc31 PF11705.3 EEQ34121.1 - 2.7e-33 115.8 26.6 5.4e-33 114.8 18.5 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 EEQ34121.1 - 0.013 15.4 4.9 0.013 15.4 3.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.6 EEQ34121.1 - 0.15 11.5 7.1 0.22 11.0 4.9 1.3 1 0 0 1 1 1 0 PPP4R2 JAB PF01398.16 EEQ34123.1 - 8.5e-10 38.3 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SAP PF02037.22 EEQ34124.1 - 5e-08 32.2 0.2 1.1e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 SAP domain DUF1772 PF08592.6 EEQ34125.1 - 0.0022 17.7 0.8 0.0092 15.7 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF401 PF04165.7 EEQ34125.1 - 0.032 13.2 1.2 0.04 12.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) adh_short_C2 PF13561.1 EEQ34126.1 - 1.7e-18 67.3 0.9 2.8e-18 66.5 0.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ34126.1 - 1.4e-16 60.8 2.2 2.5e-16 60.0 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ34126.1 - 1.6e-05 24.6 0.9 2.9e-05 23.8 0.2 1.6 2 0 0 2 2 2 1 KR domain DUF4200 PF13863.1 EEQ34127.1 - 0.00017 21.5 14.7 0.016 15.1 0.2 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 EEQ34127.1 - 0.00066 19.4 6.5 0.00066 19.4 4.5 3.0 3 1 1 4 4 2 1 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EEQ34127.1 - 0.00093 18.2 10.7 0.00093 18.2 7.4 1.6 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 WEMBL PF05701.6 EEQ34127.1 - 0.0026 16.2 19.7 0.0026 16.2 13.6 2.0 2 0 0 2 2 2 1 Weak chloroplast movement under blue light DUF3584 PF12128.3 EEQ34127.1 - 0.0039 14.6 13.1 0.0067 13.8 9.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EEQ34127.1 - 0.014 13.9 11.4 0.031 12.7 3.4 1.8 1 1 0 2 2 2 0 AAA domain CENP-Q PF13094.1 EEQ34127.1 - 0.04 13.9 16.4 0.19 11.7 11.4 2.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1986 PF09342.6 EEQ34127.1 - 0.041 13.1 1.3 0.065 12.5 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) TBPIP PF07106.8 EEQ34127.1 - 0.087 12.3 11.7 0.26 10.8 0.6 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EEQ34127.1 - 0.093 12.3 22.0 0.17 11.4 4.0 2.4 1 1 1 2 2 2 0 IncA protein MscS_porin PF12795.2 EEQ34127.1 - 0.11 11.8 27.5 0.021 14.1 12.9 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain GAS PF13851.1 EEQ34127.1 - 0.11 11.6 12.2 0.05 12.7 4.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding THOC7 PF05615.8 EEQ34127.1 - 0.11 12.7 12.8 0.7 10.1 4.2 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 XkdW PF09636.5 EEQ34127.1 - 0.19 11.6 2.4 1.1 9.1 0.2 3.2 3 0 0 3 3 3 0 XkdW protein ADIP PF11559.3 EEQ34127.1 - 0.21 11.4 16.2 0.049 13.5 2.9 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 EEQ34127.1 - 0.78 9.4 6.6 33 4.2 0.2 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Metal_resist PF13801.1 EEQ34127.1 - 0.81 9.6 13.0 1.3 9.0 4.5 3.9 3 0 0 3 3 3 0 Heavy-metal resistance DUF972 PF06156.8 EEQ34127.1 - 3 8.2 11.0 7.1 7.0 2.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 EEQ34127.1 - 3.3 7.5 16.5 0.34 10.7 3.9 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EEQ34127.1 - 4.4 7.1 26.4 0.064 13.1 2.5 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EEQ34127.1 - 4.5 6.3 17.2 0.013 14.6 2.6 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 EEQ34127.1 - 5.3 6.0 17.5 0.83 8.6 4.8 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 FimP PF09766.4 EEQ34127.1 - 6 5.8 14.9 0.32 10.0 5.2 2.4 2 1 1 3 3 3 0 Fms-interacting protein RabGAP-TBC PF00566.13 EEQ34129.1 - 4.2e-46 157.1 0.0 6.8e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.27 EEQ34129.1 - 1e-06 27.6 0.5 0.029 13.6 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EEQ34129.1 - 2e-06 27.2 2.8 0.0068 16.1 0.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EEQ34129.1 - 1.9e-05 24.7 0.9 7.1e-05 22.8 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EEQ34129.1 - 0.023 14.0 1.4 1 8.8 0.4 2.8 2 0 0 2 2 2 0 EF hand GRAM PF02893.15 EEQ34129.1 - 0.075 12.5 0.0 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 GRAM domain Sigma70_ner PF04546.8 EEQ34129.1 - 0.28 10.7 11.1 2.1 7.9 1.5 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region CNH PF00780.17 EEQ34130.1 - 5.3e-69 232.6 0.0 8.3e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EEQ34130.1 - 8.8e-32 110.4 1.5 2e-31 109.2 1.0 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EEQ34130.1 - 5.4e-15 55.5 0.0 2.2e-14 53.5 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEQ34130.1 - 0.0091 16.1 0.0 0.029 14.5 0.0 1.9 1 1 0 1 1 1 1 PH domain TORC_N PF12884.2 EEQ34130.1 - 1.5 9.3 8.7 1 9.9 0.1 4.1 3 0 0 3 3 3 0 Transducer of regulated CREB activity, N terminus 2OG-FeII_Oxy_2 PF13532.1 EEQ34131.1 - 8.7e-20 71.3 0.0 2.6e-19 69.8 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SAD_SRA PF02182.12 EEQ34131.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 SAD/SRA domain AMP-binding PF00501.23 EEQ34132.1 - 6.5e-74 248.7 0.0 8.8e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ34132.1 - 1.5e-12 48.2 0.1 3.5e-12 47.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 EEQ34133.1 - 7.2e-31 104.9 9.5 2.4e-06 27.1 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEQ34133.1 - 1.2e-06 27.9 0.0 0.012 15.0 0.0 3.4 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 EEQ34133.1 - 0.086 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus NDUF_B12 PF08122.7 EEQ34134.1 - 5.1e-19 67.7 0.7 7.5e-19 67.2 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.15 EEQ34135.1 - 2e-65 220.7 0.0 4.7e-65 219.5 0.0 1.6 2 0 0 2 2 2 1 CAF1 family ribonuclease Siva PF05458.7 EEQ34135.1 - 0.078 12.5 1.5 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Asp PF00026.18 EEQ34136.1 - 2.5e-48 164.9 0.0 2.3e-23 82.9 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEQ34136.1 - 0.0031 17.0 0.0 0.0097 15.4 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EEQ34136.1 - 0.0086 16.5 0.0 0.37 11.3 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease TPR_11 PF13414.1 EEQ34137.1 - 1.8e-11 43.4 1.8 1.4e-07 31.0 1.1 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EEQ34137.1 - 6.4e-06 25.6 5.5 0.023 14.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ34137.1 - 0.00054 19.8 5.6 0.13 12.1 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ34137.1 - 0.00078 18.9 2.4 1.2 8.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ34137.1 - 0.00083 19.1 0.1 0.0023 17.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ34137.1 - 0.0032 17.5 0.1 0.0069 16.4 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 RRM_5 PF13893.1 EEQ34137.1 - 0.077 12.8 0.0 0.26 11.1 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_8 PF13181.1 EEQ34137.1 - 0.13 12.0 1.3 14 5.7 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ34137.1 - 0.14 12.8 5.4 6 7.6 0.0 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ34137.1 - 0.54 11.0 6.3 3.9 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat GRAM PF02893.15 EEQ34138.1 - 3.3e-16 58.5 0.0 9.5e-16 57.0 0.0 1.8 2 0 0 2 2 2 1 GRAM domain Med30 PF11315.3 EEQ34139.1 - 0.0016 18.5 0.2 0.61 10.2 0.1 2.5 2 0 0 2 2 2 2 Mediator complex subunit 30 HALZ PF02183.13 EEQ34139.1 - 0.17 11.6 5.8 4.2 7.1 0.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 EEQ34139.1 - 0.88 9.1 9.6 0.3 10.6 4.3 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EEQ34139.1 - 2.4 8.5 6.6 3.9 7.8 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) CCDC-167 PF15188.1 EEQ34139.1 - 4.4 7.3 7.0 0.22 11.4 0.1 2.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Mg_trans_NIPA PF05653.9 EEQ34140.1 - 1.2e-65 221.4 8.7 5.9e-63 212.6 4.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EEQ34140.1 - 1.1e-05 25.6 0.4 1.1e-05 25.6 0.3 3.2 2 1 0 2 2 2 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EEQ34140.1 - 0.00024 20.0 1.8 0.00024 20.0 0.2 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EEQ34140.1 - 0.002 18.1 0.9 0.002 18.1 0.6 3.8 3 1 1 4 4 4 1 EamA-like transporter family RNA_capsid PF03035.9 EEQ34140.1 - 0.043 13.6 0.7 0.099 12.4 0.5 1.6 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein DoxX_2 PF13564.1 EEQ34140.1 - 2.3 8.2 11.3 2.3 8.2 0.3 3.0 3 1 1 4 4 4 0 DoxX-like family WD40 PF00400.27 EEQ34141.1 - 1.8e-15 56.1 4.7 1.2e-06 28.1 0.3 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat AAA PF00004.24 EEQ34142.1 - 6.6e-41 139.6 0.0 1.2e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ34142.1 - 3.4e-07 30.4 0.3 0.00014 21.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EEQ34142.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEQ34142.1 - 4.2e-05 23.2 0.0 0.00012 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EEQ34142.1 - 5.4e-05 22.2 0.0 9.4e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EEQ34142.1 - 0.00067 19.6 0.3 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ34142.1 - 0.00093 19.2 0.1 0.008 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EEQ34142.1 - 0.0012 17.9 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEQ34142.1 - 0.0014 18.3 0.4 0.0032 17.1 0.3 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EEQ34142.1 - 0.0041 16.5 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EEQ34142.1 - 0.0082 15.2 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EEQ34142.1 - 0.01 15.4 0.5 0.72 9.4 0.1 3.0 2 1 0 3 3 3 0 NACHT domain AAA_14 PF13173.1 EEQ34142.1 - 0.015 15.1 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ34142.1 - 0.019 15.7 0.3 0.054 14.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EEQ34142.1 - 0.023 13.8 0.4 0.29 10.1 0.1 2.2 1 1 0 2 2 2 0 KaiC TIP49 PF06068.8 EEQ34142.1 - 0.027 13.1 1.7 0.033 12.9 0.1 1.9 2 1 0 2 2 2 0 TIP49 C-terminus AAA_3 PF07726.6 EEQ34142.1 - 0.032 13.8 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEQ34142.1 - 0.045 14.0 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEQ34142.1 - 0.049 13.5 0.1 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EEQ34142.1 - 0.063 12.4 1.3 0.47 9.6 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 EEQ34142.1 - 0.063 12.1 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 EEQ34142.1 - 0.08 11.8 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EEQ34142.1 - 0.086 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EEQ34142.1 - 0.12 11.4 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EEQ34142.1 - 0.16 12.2 0.6 1.1 9.5 0.4 2.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EEQ34142.1 - 0.29 10.6 1.7 0.36 10.3 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EEQ34142.1 - 0.35 10.2 5.1 0.72 9.2 0.3 2.6 2 1 0 3 3 3 0 AAA domain APH PF01636.18 EEQ34143.1 - 3.7e-12 46.5 0.0 2.2e-11 43.9 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family UQ_con PF00179.21 EEQ34144.1 - 2.2e-43 147.0 0.0 2.9e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EEQ34144.1 - 2.6e-05 23.7 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EEQ34144.1 - 5.2e-05 23.0 0.0 8.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ34144.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EEQ34144.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Cyclin_N PF00134.18 EEQ34145.1 - 2.7e-06 26.9 0.1 1.3e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain ABC_tran PF00005.22 EEQ34146.1 - 1.7e-48 164.4 0.0 1.4e-23 83.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEQ34146.1 - 8.9e-21 75.1 0.7 0.00048 20.1 0.0 4.3 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EEQ34146.1 - 2.6e-20 72.0 2.2 2.6e-20 72.0 1.6 2.6 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 EEQ34146.1 - 3.8e-11 42.6 0.4 0.00066 18.9 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEQ34146.1 - 9.2e-10 37.9 0.4 0.00051 19.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EEQ34146.1 - 1.7e-08 35.0 4.8 0.027 14.7 0.1 4.0 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 EEQ34146.1 - 5.4e-07 28.9 0.0 0.0011 18.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ34146.1 - 1.9e-06 28.6 0.0 0.017 15.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEQ34146.1 - 4e-06 27.1 0.0 0.03 14.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EEQ34146.1 - 7.1e-06 26.5 0.0 0.026 15.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EEQ34146.1 - 8.9e-06 25.8 0.0 0.15 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EEQ34146.1 - 9.3e-06 25.6 0.0 0.0075 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EEQ34146.1 - 1.5e-05 24.9 0.2 0.082 12.8 0.2 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 EEQ34146.1 - 3.6e-05 23.9 0.0 0.51 10.5 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EEQ34146.1 - 4e-05 23.3 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 EEQ34146.1 - 4.8e-05 23.4 0.2 0.34 10.8 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EEQ34146.1 - 7.2e-05 21.9 0.2 0.14 11.2 0.0 3.0 5 0 0 5 5 4 2 AAA ATPase domain AAA_33 PF13671.1 EEQ34146.1 - 0.00015 21.6 2.5 0.089 12.6 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 EEQ34146.1 - 0.00017 21.0 0.0 0.74 9.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 EEQ34146.1 - 0.00017 21.4 0.7 0.56 10.0 0.0 3.6 3 1 1 4 4 4 1 Dynamin family Arch_ATPase PF01637.13 EEQ34146.1 - 0.00018 21.2 0.6 0.7 9.5 0.0 3.6 3 1 1 4 4 4 1 Archaeal ATPase RNA_helicase PF00910.17 EEQ34146.1 - 0.00019 21.5 0.4 1.3 9.2 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_5 PF07728.9 EEQ34146.1 - 0.00022 20.9 0.1 0.72 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EEQ34146.1 - 0.0011 17.9 0.1 0.44 9.3 0.0 3.1 2 1 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 EEQ34146.1 - 0.0014 18.1 0.5 2.4 7.5 0.2 2.9 4 0 0 4 4 2 2 AAA-like domain MobB PF03205.9 EEQ34146.1 - 0.0014 18.2 0.2 0.088 12.5 0.1 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EEQ34146.1 - 0.0015 18.4 0.0 2.9 7.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EEQ34146.1 - 0.004 17.0 0.6 0.46 10.4 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.8 EEQ34146.1 - 0.0043 16.0 0.0 0.4 9.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF2813 PF11398.3 EEQ34146.1 - 0.013 14.6 1.0 2.4 7.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) DAP3 PF10236.4 EEQ34146.1 - 0.014 14.3 0.7 2.1 7.2 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 VirE PF05272.6 EEQ34146.1 - 0.016 14.6 0.2 1.5 8.2 0.0 3.1 3 0 0 3 3 3 0 Virulence-associated protein E ATP-synt_ab PF00006.20 EEQ34146.1 - 0.021 14.3 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EEQ34146.1 - 0.024 14.3 0.0 3.5 7.2 0.0 2.6 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 EEQ34146.1 - 0.052 13.0 1.3 4 6.9 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.18 EEQ34146.1 - 0.14 10.9 2.0 4.6 5.9 0.0 2.5 3 0 0 3 3 3 0 MCM2/3/5 family AAA_13 PF13166.1 EEQ34146.1 - 0.17 10.3 7.5 5.5 5.3 0.1 4.1 4 1 0 4 4 4 0 AAA domain HPP PF04982.8 EEQ34147.1 - 5.6e-37 126.2 6.0 5.6e-37 126.2 4.2 1.6 2 0 0 2 2 2 1 HPP family DUF599 PF04654.7 EEQ34147.1 - 0.055 12.6 1.6 4.3 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF599 Yip1 PF04893.12 EEQ34147.1 - 0.35 10.3 10.3 1.9 7.9 3.4 2.6 1 1 1 2 2 2 0 Yip1 domain ABC_cobalt PF09819.4 EEQ34147.1 - 0.42 10.5 3.0 0.77 9.7 2.0 1.5 1 1 0 1 1 1 0 ABC-type cobalt transport system, permease component DUF4231 PF14015.1 EEQ34147.1 - 5.5 7.0 8.1 12 5.9 0.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) GFO_IDH_MocA PF01408.17 EEQ34149.1 - 1.7e-25 89.8 0.1 3.2e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEQ34149.1 - 2e-13 50.1 0.0 3.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EEQ34149.1 - 5.1e-07 30.1 0.2 1.2e-06 28.9 0.1 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EEQ34149.1 - 0.0002 21.2 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EEQ34149.1 - 0.00027 21.2 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.14 EEQ34149.1 - 0.0013 19.2 0.2 0.0039 17.6 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain F420_oxidored PF03807.12 EEQ34149.1 - 0.029 14.8 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent YhjQ PF06564.7 EEQ34149.1 - 0.035 13.4 0.1 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 YhjQ protein MARVEL PF01284.18 EEQ34150.1 - 0.00077 19.2 5.6 0.0015 18.3 3.9 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF605 PF04652.11 EEQ34150.1 - 0.027 13.8 0.2 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 Vta1 like SR-25 PF10500.4 EEQ34151.1 - 0.00024 20.6 6.0 0.00049 19.6 4.2 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RRM_1 PF00076.17 EEQ34153.1 - 3.2e-15 55.5 0.1 7.4e-14 51.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ34153.1 - 5.9e-13 48.5 0.0 1.5e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ34153.1 - 0.0062 16.3 0.0 0.039 13.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.1 EEQ34155.1 - 2.4e-07 30.7 11.9 1e-05 25.5 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ34155.1 - 1.8e-06 27.8 13.9 0.00019 21.5 4.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EEQ34155.1 - 0.00045 20.2 4.7 0.00097 19.2 3.3 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EEQ34155.1 - 0.0028 17.7 4.7 0.06 13.5 0.7 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EEQ34155.1 - 0.0029 17.8 16.8 0.019 15.3 4.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.2 EEQ34155.1 - 0.17 11.6 1.4 0.29 10.9 1.0 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 EEQ34155.1 - 0.21 11.4 7.4 0.16 11.7 0.6 2.5 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.2 EEQ34155.1 - 0.61 10.3 5.3 1.9 8.8 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EEQ34155.1 - 5.8 6.6 8.4 9 6.0 0.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type QCR10 PF09796.4 EEQ34156.1 - 1.9e-22 78.7 0.1 2.5e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) APG5 PF04106.7 EEQ34157.1 - 5.1e-64 215.3 0.0 6.1e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Zip PF02535.17 EEQ34158.1 - 0.15 11.0 7.3 0.18 10.7 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 EEQ34158.1 - 2.2 7.0 6.7 2.7 6.7 4.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 EEQ34158.1 - 2.8 7.2 13.0 3.9 6.7 9.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MFS_1 PF07690.11 EEQ34159.1 - 3.3e-18 65.5 56.7 3.3e-18 65.5 39.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Arrestin_N PF00339.24 EEQ34161.1 - 1.2e-16 60.9 0.4 2e-14 53.6 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain CCSMST1 PF15013.1 EEQ34161.1 - 0.19 11.6 1.1 0.41 10.6 0.7 1.6 1 0 0 1 1 1 0 CCSMST1 family HRXXH PF13933.1 EEQ34162.1 - 4.8e-05 22.8 0.0 0.00013 21.4 0.0 1.7 1 0 0 1 1 1 1 Putative peptidase family SHR3_chaperone PF08229.6 EEQ34164.1 - 6.3e-78 260.2 0.0 8.2e-78 259.8 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 MLANA PF14991.1 EEQ34164.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A ArfGap PF01412.13 EEQ34166.1 - 4.1e-33 113.6 0.0 9.4e-32 109.2 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.22 EEQ34167.1 - 6.3e-54 182.2 0.0 9.8e-54 181.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EEQ34167.1 - 5.8e-24 83.7 0.0 1.4e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EEQ34167.1 - 1.1e-17 63.6 0.1 8.7e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEQ34167.1 - 9.7e-06 25.6 0.0 5.2e-05 23.2 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EEQ34167.1 - 0.0014 18.2 0.4 0.29 10.7 0.0 3.0 4 0 0 4 4 4 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EEQ34167.1 - 0.087 12.7 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Vps5 PF09325.5 EEQ34168.1 - 1.6e-13 50.4 3.5 2.7e-13 49.7 2.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EEQ34168.1 - 1.3e-08 34.5 0.0 2.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 PX domain GFA PF04828.9 EEQ34169.1 - 1.1e-16 60.4 0.1 1.8e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Tho2 PF11262.3 EEQ34170.1 - 7.9e-94 314.0 0.0 1.2e-93 313.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EEQ34170.1 - 2.9e-29 100.6 0.0 6.9e-29 99.4 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit MFS_1 PF07690.11 EEQ34172.1 - 3.2e-35 121.4 26.1 5.1e-35 120.8 18.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MASE2 PF05230.6 EEQ34172.1 - 0.029 14.3 0.8 0.11 12.4 0.6 2.0 1 0 0 1 1 1 0 MASE2 domain DUF4231 PF14015.1 EEQ34172.1 - 6.2 6.8 5.8 1.4 8.8 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Gly_transf_sug PF04488.10 EEQ34173.1 - 3.1e-17 62.8 0.1 1.2e-16 60.9 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EEQ34173.1 - 0.0015 17.7 0.2 0.0055 15.9 0.0 1.8 2 0 0 2 2 2 1 Capsular polysaccharide synthesis protein BPD_transp_1 PF00528.17 EEQ34173.1 - 0.0035 16.8 4.9 0.089 12.2 0.2 2.3 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component TcdA_TcdB PF12919.2 EEQ34173.1 - 0.28 9.6 5.0 0.23 9.9 0.5 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Abhydrolase_1 PF00561.15 EEQ34174.1 - 1.1e-40 139.5 0.1 3.7e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ34174.1 - 1.1e-11 45.0 0.3 9e-11 42.0 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ34174.1 - 0.0023 17.7 0.0 0.021 14.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EEQ34174.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF706 PF05153.10 EEQ34178.1 - 4.7e-126 419.2 3.2 5.7e-126 418.9 2.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EEQ34178.1 - 0.11 12.5 0.9 0.79 9.7 0.0 2.5 3 0 0 3 3 3 0 HD domain Exo_endo_phos PF03372.18 EEQ34179.1 - 5.3e-16 59.3 1.2 7.4e-16 58.8 0.8 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RTC PF01137.16 EEQ34180.1 - 1.9e-32 111.9 0.0 3e-27 94.8 0.0 3.2 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase TSC21 PF15217.1 EEQ34182.1 - 0.091 12.4 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 TSC21 family SH3_9 PF14604.1 EEQ34183.1 - 1.2e-13 50.3 0.1 2.5e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ34183.1 - 1.2e-12 46.9 0.1 2.2e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EEQ34183.1 - 2.6e-12 46.7 0.1 3.8e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EEQ34183.1 - 1.4e-10 40.4 0.1 4.6e-10 38.8 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain U1snRNP70_N PF12220.3 EEQ34183.1 - 2.1 8.7 6.8 0.62 10.4 1.7 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2439 PF10382.4 EEQ34184.1 - 2.7e-26 91.6 0.0 5.1e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Methyltransf_23 PF13489.1 EEQ34185.1 - 4.8e-15 55.6 0.0 6.9e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ34185.1 - 1.2e-06 28.9 0.0 1.4e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ34185.1 - 2.7e-06 27.7 0.0 1.3e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ34185.1 - 2.8e-06 27.0 0.0 9.7e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ34185.1 - 2.1e-05 25.0 0.0 3.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Mcp5_PH PF12814.2 EEQ34186.1 - 1.2e-42 144.7 0.2 2.2e-42 143.8 0.2 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology zf-C3HC4_2 PF13923.1 EEQ34187.1 - 3.2e-08 33.4 10.1 5.5e-08 32.7 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ34187.1 - 7.7e-08 31.8 5.2 1.2e-07 31.2 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EEQ34187.1 - 1.7e-07 30.7 2.3 3.1e-07 29.9 1.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EEQ34187.1 - 1.9e-06 27.5 6.5 3.1e-06 26.8 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ34187.1 - 2.3e-06 27.1 8.4 4e-06 26.4 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEQ34187.1 - 3e-06 26.7 10.0 5.3e-06 25.9 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEQ34187.1 - 0.0069 16.0 5.2 0.016 14.9 3.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Cript PF10235.4 EEQ34187.1 - 0.011 16.0 2.2 0.062 13.6 1.6 2.2 2 1 1 3 3 2 0 Microtubule-associated protein CRIPT zf-C3HC4_4 PF15227.1 EEQ34187.1 - 0.011 15.5 8.6 0.025 14.4 5.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EEQ34187.1 - 0.25 10.8 3.0 0.44 10.1 2.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit BLVR PF06375.6 EEQ34187.1 - 0.58 9.9 0.0 0.58 9.9 0.0 2.8 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) zf-rbx1 PF12678.2 EEQ34187.1 - 0.66 10.1 5.5 1.6 8.8 3.8 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger DUF4611 PF15387.1 EEQ34187.1 - 3.1 8.0 7.7 5.9 7.1 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3431 PF11913.3 EEQ34188.1 - 4.1e-80 268.4 0.4 1.3e-79 266.8 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Myb_DNA-bind_6 PF13921.1 EEQ34189.1 - 2.3e-05 24.4 0.1 0.00012 22.0 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ34189.1 - 0.025 14.6 0.3 0.061 13.3 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pkinase PF00069.20 EEQ34190.1 - 5.7e-59 199.3 0.1 1.6e-58 197.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34190.1 - 8.2e-28 97.1 0.1 5.7e-26 91.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 EEQ34190.1 - 1.1e-07 31.8 0.0 3.2e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 FHA domain APH PF01636.18 EEQ34190.1 - 0.0003 20.5 0.0 0.00086 19.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ34190.1 - 0.00047 19.2 0.0 0.00077 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ34190.1 - 0.0026 16.8 0.0 0.005 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 EEQ34191.1 - 1e-66 225.3 0.0 1.2e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3542 PF12061.3 EEQ34191.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) P2X_receptor PF00864.14 EEQ34192.1 - 0.017 13.8 0.1 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 ATP P2X receptor Ank_5 PF13857.1 EEQ34193.1 - 1e-05 25.6 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EEQ34193.1 - 0.00043 19.9 0.1 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 EEQ34193.1 - 0.00055 19.9 0.1 0.002 18.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EEQ34193.1 - 0.0022 18.4 0.0 0.0056 17.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ34193.1 - 0.0066 16.7 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) ABC_membrane PF00664.18 EEQ34194.1 - 3.5e-82 275.9 31.1 3.6e-45 154.4 7.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ34194.1 - 3e-51 173.2 0.0 1.3e-30 106.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ34194.1 - 4e-09 36.0 3.7 0.00034 19.9 0.4 4.1 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEQ34194.1 - 2.9e-07 30.6 3.2 0.0045 16.9 0.9 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EEQ34194.1 - 5.6e-06 25.6 0.3 0.0029 16.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EEQ34194.1 - 6.3e-06 26.1 0.1 0.24 11.3 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EEQ34194.1 - 4e-05 23.0 0.5 0.33 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ34194.1 - 0.0003 20.2 0.3 0.64 9.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EEQ34194.1 - 0.0006 19.8 1.5 2.1 8.2 0.0 4.0 3 1 0 4 4 3 1 AAA domain Miro PF08477.8 EEQ34194.1 - 0.0015 19.0 1.1 1.9 9.0 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EEQ34194.1 - 0.0035 17.1 0.6 0.52 10.1 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.1 EEQ34194.1 - 0.0073 15.9 2.7 2.7 7.5 0.2 3.4 3 1 0 3 3 2 1 AAA domain AAA_23 PF13476.1 EEQ34194.1 - 0.0094 16.2 0.1 0.65 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EEQ34194.1 - 0.015 15.1 2.9 2.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EEQ34194.1 - 0.044 13.2 0.0 5 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EEQ34194.1 - 0.045 12.8 0.2 6.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 EEQ34194.1 - 0.069 13.3 0.0 4.8 7.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 EEQ34194.1 - 0.073 13.8 0.0 7.2 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEQ34194.1 - 0.091 12.1 4.4 2.6 7.3 0.1 3.1 2 1 0 3 3 3 0 AAA-like domain AAA_22 PF13401.1 EEQ34194.1 - 0.094 12.8 3.0 5.3 7.2 0.1 3.2 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EEQ34194.1 - 0.14 11.5 0.1 18 4.7 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EEQ34194.1 - 0.21 11.2 1.7 14 5.3 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2841 PF11001.3 EEQ34196.1 - 5.9e-49 165.1 0.1 1e-48 164.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Mpt_N PF09176.6 EEQ34197.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Zip PF02535.17 EEQ34198.1 - 4.7e-44 150.6 5.6 6e-44 150.3 3.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Phage_holin_1 PF04531.8 EEQ34198.1 - 0.012 15.6 0.5 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage holin SAC3_GANP PF03399.11 EEQ34199.1 - 5.9e-54 182.7 2.4 8.4e-54 182.2 1.6 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEQ34199.1 - 0.0019 17.9 0.4 0.0047 16.7 0.3 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 MIP-T3 PF10243.4 EEQ34199.1 - 5.1 5.4 45.9 12 4.1 31.8 1.6 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CN_hydrolase PF00795.17 EEQ34200.1 - 4.9e-12 45.5 0.0 2.5e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase HLH PF00010.21 EEQ34201.1 - 4.3e-12 45.5 1.0 8.7e-12 44.5 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain tRNA_bind_2 PF13725.1 EEQ34201.1 - 0.094 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Possible tRNA binding domain DUF2681 PF10883.3 EEQ34201.1 - 0.24 11.6 7.3 0.48 10.6 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2780 PF11075.3 EEQ34201.1 - 3 7.8 6.5 2.4 8.1 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) Peptidase_S64 PF08192.6 EEQ34202.1 - 9.2e-05 20.9 0.0 0.00014 20.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.8 EEQ34202.1 - 0.0082 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S7 PF00949.16 EEQ34202.1 - 0.013 14.8 0.0 0.033 13.5 0.0 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Trypsin_2 PF13365.1 EEQ34202.1 - 0.035 14.0 0.1 0.17 11.8 0.1 2.2 1 1 0 1 1 1 0 Trypsin-like peptidase domain BTB_2 PF02214.17 EEQ34203.1 - 8.8e-08 32.2 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EEQ34203.1 - 2.6e-06 27.3 0.0 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Resistin PF06954.6 EEQ34203.1 - 0.15 12.3 1.2 2.4 8.5 0.1 2.3 1 1 1 2 2 2 0 Resistin polyprenyl_synt PF00348.12 EEQ34204.1 - 3.2e-61 206.4 0.0 4e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1771 PF08590.5 EEQ34205.1 - 9.2e-23 80.0 4.4 9.2e-23 80.0 3.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EEQ34205.1 - 6.6e-17 61.4 0.4 1.7e-16 60.1 0.3 1.8 1 0 0 1 1 1 1 Smr domain DUF605 PF04652.11 EEQ34205.1 - 1.5 8.1 5.7 18 4.6 4.0 2.0 2 0 0 2 2 2 0 Vta1 like Zip PF02535.17 EEQ34205.1 - 7.6 5.4 6.8 9.5 5.1 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pyrid_oxidase_2 PF13883.1 EEQ34206.1 - 6.1e-35 120.4 0.0 9e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ipi1_N PF12333.3 EEQ34208.1 - 1.7e-28 98.5 1.7 4.6e-28 97.1 0.0 2.3 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.12 EEQ34209.1 - 2.5e-05 23.7 0.1 0.029 13.9 0.0 2.9 3 0 0 3 3 3 2 Roadblock/LC7 domain MRI PF15325.1 EEQ34209.1 - 0.037 15.0 1.0 0.037 15.0 0.7 2.1 1 1 1 2 2 2 0 Modulator of retrovirus infection DUF4449 PF14613.1 EEQ34210.1 - 0.036 14.0 1.0 0.043 13.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF4657 PF15552.1 EEQ34210.1 - 0.11 11.7 0.5 0.13 11.4 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) YtxH PF12732.2 EEQ34210.1 - 0.11 12.8 1.7 0.16 12.3 1.2 1.2 1 0 0 1 1 1 0 YtxH-like protein ISG65-75 PF11727.3 EEQ34210.1 - 0.75 8.8 3.2 0.99 8.3 2.2 1.3 1 1 0 1 1 1 0 Invariant surface glycoprotein Dehydrin PF00257.14 EEQ34210.1 - 1.5 9.1 7.9 2.6 8.3 5.5 1.4 1 1 0 1 1 1 0 Dehydrin Aa_trans PF01490.13 EEQ34212.1 - 4.7e-38 130.7 37.6 6.1e-38 130.3 26.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EEQ34212.1 - 0.007 15.9 3.8 0.007 15.9 2.7 3.5 3 1 1 4 4 4 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Tetraspannin PF00335.15 EEQ34212.1 - 0.082 12.1 0.2 0.082 12.1 0.1 4.8 4 1 0 5 5 5 0 Tetraspanin family ETRAMP PF09716.5 EEQ34212.1 - 7.9 6.5 6.1 36 4.4 1.8 3.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Tubulin PF00091.20 EEQ34213.1 - 1.8e-75 253.4 0.0 2.7e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEQ34213.1 - 2.1e-43 147.3 0.8 3.1e-43 146.8 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EEQ34213.1 - 9.1e-08 32.1 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain HisG PF01634.13 EEQ34213.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP phosphoribosyltransferase CASP_C PF08172.7 EEQ34213.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 CASP C terminal Asp_Glu_race PF01177.17 EEQ34214.1 - 5.8e-14 52.5 0.0 8.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF883 PF05957.8 EEQ34214.1 - 0.047 14.0 0.4 0.1 13.0 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Aldo_ket_red PF00248.16 EEQ34215.1 - 3.9e-55 186.6 0.0 4.5e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.15 EEQ34216.1 - 8.1e-06 25.9 1.3 8.1e-06 25.9 0.9 2.2 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EEQ34216.1 - 0.00031 20.9 0.9 0.00031 20.9 0.6 2.0 2 0 0 2 2 2 1 Multidrug resistance efflux transporter 7TMR-DISM_7TM PF07695.6 EEQ34216.1 - 0.019 14.6 0.8 0.019 14.6 0.5 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF2892 PF11127.3 EEQ34216.1 - 0.033 14.0 0.6 0.033 14.0 0.4 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) DUF1908 PF08926.6 EEQ34216.1 - 4.5 5.9 6.3 6.2 5.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Actin PF00022.14 EEQ34217.1 - 8.3e-91 304.3 0.0 1.2e-90 303.8 0.0 1.2 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEQ34217.1 - 0.2 10.2 0.0 0.7 8.4 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein DUF3425 PF11905.3 EEQ34218.1 - 2.5e-35 121.3 3.2 4.7e-35 120.4 2.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Orexin_rec2 PF03827.8 EEQ34218.1 - 0.048 13.7 0.3 2.1 8.4 0.0 3.1 3 0 0 3 3 3 0 Orexin receptor type 2 BMFP PF04380.8 EEQ34218.1 - 0.053 13.6 2.6 0.13 12.4 1.8 1.6 1 0 0 1 1 1 0 Membrane fusogenic activity bZIP_1 PF00170.16 EEQ34218.1 - 0.15 12.0 11.7 0.61 10.0 8.1 2.0 1 1 0 1 1 1 0 bZIP transcription factor SOBP PF15279.1 EEQ34218.1 - 4.1 7.7 17.9 1.6 9.0 9.7 1.9 1 1 1 2 2 2 0 Sine oculis-binding protein Fungal_trans PF04082.13 EEQ34219.1 - 2.9e-08 32.8 0.0 5.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ34219.1 - 4e-08 33.0 7.6 4e-08 33.0 5.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_31 PF13847.1 EEQ34220.1 - 8.5e-15 54.6 0.0 1.1e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ34220.1 - 1.5e-14 54.0 0.0 2.1e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ34220.1 - 2.6e-13 50.2 0.0 4.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ34220.1 - 1.4e-11 44.9 0.0 2.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ34220.1 - 2.5e-11 43.9 0.0 4.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ34220.1 - 9.6e-10 38.7 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ34220.1 - 1.7e-06 27.3 0.0 5.4e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EEQ34220.1 - 0.0001 21.9 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ34220.1 - 0.00066 19.6 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EEQ34220.1 - 0.0054 15.6 0.0 0.027 13.3 0.0 1.9 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EEQ34220.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EEQ34220.1 - 0.02 15.7 0.0 0.036 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_19 PF04672.7 EEQ34220.1 - 0.043 13.0 0.0 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase GTP_cyclohydro2 PF00925.15 EEQ34221.1 - 1.2e-57 193.7 0.0 2.5e-52 176.5 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF1325 PF07039.6 EEQ34222.1 - 4.2e-31 107.2 0.0 6.7e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Ribosomal_L18ae PF01775.12 EEQ34222.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L18ae/LX protein domain PMI_typeI PF01238.16 EEQ34223.1 - 7.3e-148 492.5 0.0 8.6e-148 492.2 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF2424 PF10340.4 EEQ34224.1 - 1.2e-22 80.0 0.0 1.7e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EEQ34224.1 - 1.4e-22 80.2 0.0 2.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ34224.1 - 4.7e-05 23.1 0.0 7.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ34224.1 - 0.00057 19.1 0.0 0.015 14.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.3 EEQ34224.1 - 0.038 13.3 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Coatomer_E PF04733.9 EEQ34225.1 - 2.9e-61 207.2 8.9 3.3e-61 207.0 6.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EEQ34225.1 - 3.4e-09 36.8 20.6 0.00056 20.1 1.9 4.6 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ34225.1 - 2.4e-07 30.7 18.6 0.00094 19.6 0.0 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ34225.1 - 4.6e-06 27.1 21.2 0.00091 19.8 0.0 4.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ34225.1 - 4.5e-05 23.6 3.0 0.14 12.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ34225.1 - 0.00015 21.8 6.7 0.049 13.7 1.2 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.7 EEQ34225.1 - 0.0011 18.5 0.2 0.0028 17.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF627) NTP_transferase PF00483.18 EEQ34225.1 - 0.021 14.1 1.1 0.034 13.4 0.8 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase Peptidase_S11 PF00768.15 EEQ34225.1 - 0.037 13.2 0.4 0.05 12.8 0.3 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase TPR_11 PF13414.1 EEQ34225.1 - 0.038 13.6 8.8 0.046 13.3 0.0 4.1 3 1 0 4 4 4 0 TPR repeat TPR_4 PF07721.9 EEQ34225.1 - 0.065 13.6 24.3 0.31 11.5 0.5 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ34225.1 - 0.071 13.0 0.0 0.071 13.0 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ34225.1 - 0.12 12.0 5.6 0.52 10.0 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ34225.1 - 0.15 11.9 11.2 4 7.4 2.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ34225.1 - 0.26 11.1 6.7 1.3 8.9 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EEQ34226.1 - 7.8e-08 31.5 0.6 1.3e-07 30.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF21 PF01595.15 EEQ34226.1 - 0.097 11.9 0.2 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF21 MFS_1 PF07690.11 EEQ34227.1 - 2e-35 122.1 78.2 3.6e-28 98.3 31.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ34227.1 - 4e-05 23.3 6.2 0.00048 19.8 1.8 3.1 3 0 0 3 3 3 1 MFS_1 like family Sugar_tr PF00083.19 EEQ34227.1 - 8.1e-05 21.3 33.8 0.00029 19.5 4.3 3.6 1 1 1 3 3 3 3 Sugar (and other) transporter AA_permease PF00324.16 EEQ34229.1 - 1.2e-119 399.7 39.0 1.5e-119 399.4 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ34229.1 - 1.4e-34 119.3 44.2 1.9e-34 118.9 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM213 PF15192.1 EEQ34229.1 - 0.06 13.3 0.3 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 TMEM213 family APH PF01636.18 EEQ34230.1 - 3.1e-14 53.3 0.0 2e-13 50.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ34230.1 - 0.099 11.7 0.0 9.9 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain FTA4 PF13093.1 EEQ34231.1 - 4.1e-70 235.5 0.1 4.8e-70 235.3 0.1 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3166 PF11365.3 EEQ34231.1 - 0.016 15.6 1.8 0.72 10.3 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Macoilin PF09726.4 EEQ34232.1 - 0.083 11.1 2.0 0.093 11.0 1.4 1.1 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 EEQ34232.1 - 0.11 12.9 0.6 1.1 9.7 0.1 2.5 2 0 0 2 2 2 0 SlyX HAUS6_N PF14661.1 EEQ34232.1 - 0.73 9.1 5.3 7.9 5.7 3.3 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HAD_2 PF13419.1 EEQ34233.1 - 9.1e-13 48.8 0.0 1.8e-12 47.8 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ34233.1 - 0.00074 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEQ34233.1 - 0.032 14.6 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L18p PF00861.17 EEQ34234.1 - 1.4e-43 147.8 0.3 3.5e-43 146.6 0.2 1.7 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EEQ34234.1 - 1.2e-32 112.3 4.9 1.2e-32 112.3 3.4 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF4284 PF14112.1 EEQ34234.1 - 0.33 11.4 2.7 0.69 10.4 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4284) LRR_6 PF13516.1 EEQ34235.1 - 0.0053 16.6 3.3 76 3.8 0.0 6.8 7 0 0 7 7 7 0 Leucine Rich repeat DUF3135 PF11333.3 EEQ34235.1 - 0.015 15.3 0.2 0.097 12.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) LRR_7 PF13504.1 EEQ34235.1 - 3.1 8.3 8.9 85 4.0 0.1 5.9 7 0 0 7 7 7 0 Leucine rich repeat ABC_membrane_2 PF06472.10 EEQ34236.1 - 4.6e-102 340.9 1.2 6.6e-102 340.4 0.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EEQ34236.1 - 1.7e-18 67.2 0.0 3.2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEQ34236.1 - 0.00011 22.2 0.0 0.00035 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEQ34236.1 - 0.0059 16.1 0.1 0.02 14.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EEQ34236.1 - 0.01 16.1 0.1 0.028 14.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EEQ34236.1 - 0.028 13.6 0.0 0.089 12.0 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEQ34236.1 - 0.029 14.3 0.2 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EEQ34236.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EEQ34236.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 p450 PF00067.17 EEQ34237.1 - 1.8e-41 142.1 0.3 2.3e-23 82.4 0.0 2.8 2 1 1 3 3 3 3 Cytochrome P450 APH PF01636.18 EEQ34238.1 - 3.7e-12 46.4 0.0 5.8e-12 45.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ34238.1 - 0.0015 17.7 0.0 0.023 13.8 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Choline_kinase PF01633.15 EEQ34238.1 - 0.0072 15.9 0.1 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase PDZ_1 PF12812.2 EEQ34238.1 - 0.13 12.1 0.1 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 PDZ-like domain APH PF01636.18 EEQ34239.1 - 1.1e-22 80.9 0.0 1.5e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ34239.1 - 2.4e-05 24.0 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3613 PF12266.3 EEQ34239.1 - 0.13 11.8 0.2 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) Phosphorylase PF00343.15 EEQ34241.1 - 0 1068.5 0.1 0 1068.3 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Rsa3 PF14615.1 EEQ34241.1 - 0.0061 15.8 0.0 0.04 13.1 0.0 2.3 2 0 0 2 2 2 1 Ribosome-assembly protein 3 G-alpha PF00503.15 EEQ34242.1 - 5.4e-125 417.1 0.7 6.2e-125 416.9 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEQ34242.1 - 7.2e-16 57.9 1.6 2.3e-10 39.9 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ34242.1 - 8.5e-05 21.8 0.3 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EEQ34242.1 - 0.00062 20.2 0.1 0.28 11.6 0.0 2.6 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EEQ34242.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.20 EEQ34243.1 - 4.5e-72 242.3 0.0 5.5e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34243.1 - 3.5e-32 111.5 0.0 4.8e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ34243.1 - 1.9e-05 23.8 0.0 6.8e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ34243.1 - 0.00047 19.9 0.1 0.0019 17.9 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ34243.1 - 0.00053 19.0 0.0 0.02 13.8 0.0 2.1 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EEQ34243.1 - 0.044 13.1 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.4 EEQ34244.1 - 1.2e-144 481.4 0.0 1.8e-144 480.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EEQ34244.1 - 1.6e-09 37.4 2.8 5.5e-08 32.4 0.1 3.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EEQ34244.1 - 2.1e-08 33.8 0.3 0.00051 19.7 0.0 2.4 1 1 0 2 2 2 2 Stabilization of polarity axis Cullin PF00888.17 EEQ34245.1 - 2.2e-189 630.8 6.8 3.3e-189 630.2 4.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEQ34245.1 - 9.9e-28 95.7 3.8 9.9e-28 95.7 2.7 2.7 3 0 0 3 3 3 1 Cullin protein neddylation domain WGG PF10273.4 EEQ34245.1 - 0.099 12.7 0.2 27 4.9 0.0 3.2 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 Abi_C PF14355.1 EEQ34245.1 - 0.13 12.2 0.6 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 Abortive infection C-terminus Kinase-PPPase PF03618.9 EEQ34245.1 - 2.3 7.6 9.4 5.2 6.4 0.4 2.3 2 0 0 2 2 2 0 Kinase/pyrophosphorylase MARVEL PF01284.18 EEQ34246.1 - 0.0023 17.7 3.0 0.0035 17.1 2.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain KcnmB2_inactiv PF09303.5 EEQ34246.1 - 0.0096 15.6 0.2 0.0096 15.6 0.2 1.9 2 0 0 2 2 2 1 KCNMB2, ball and chain domain Ilm1 PF10311.4 EEQ34246.1 - 0.065 12.7 0.5 0.11 11.9 0.4 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF1418 PF07214.7 EEQ34246.1 - 0.26 10.9 0.1 0.26 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF605 PF04652.11 EEQ34246.1 - 8.2 5.7 10.4 11 5.3 7.2 1.1 1 0 0 1 1 1 0 Vta1 like Mit_KHE1 PF10173.4 EEQ34247.1 - 3.4e-68 229.1 1.2 4.7e-68 228.7 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related APH PF01636.18 EEQ34248.1 - 2.7e-20 73.1 0.0 1e-19 71.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ34248.1 - 3.3e-05 22.7 0.2 0.062 11.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEQ34248.1 - 0.00023 20.4 0.0 0.00042 19.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 EEQ34248.1 - 0.008 15.1 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase End3 PF12761.2 EEQ34249.1 - 1.1e-77 260.0 1.8 1.6e-77 259.5 1.2 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EEQ34249.1 - 5.3e-52 173.9 0.2 9.7e-50 166.6 0.1 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EEQ34249.1 - 1.1e-07 30.6 0.2 3.9e-07 28.8 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EEQ34249.1 - 5.3e-06 25.9 0.2 2.8e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ34249.1 - 8.9e-06 25.1 0.1 0.00024 20.7 0.2 2.8 3 0 0 3 3 2 1 EF-hand domain EF-hand_7 PF13499.1 EEQ34249.1 - 2e-05 24.6 0.2 0.0002 21.4 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 EEQ34249.1 - 0.00077 18.6 1.0 0.0026 17.0 0.2 2.3 2 0 0 2 2 2 1 EF hand DUF4407 PF14362.1 EEQ34249.1 - 0.0026 16.7 4.6 0.0043 16.0 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Rabaptin PF03528.10 EEQ34249.1 - 0.019 14.8 7.8 0.21 11.5 5.4 2.6 2 1 1 3 3 2 0 Rabaptin Phage_GP20 PF06810.6 EEQ34249.1 - 0.025 14.0 3.8 0.034 13.5 0.4 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 Med9 PF07544.8 EEQ34249.1 - 0.04 13.6 0.7 0.04 13.6 0.5 2.6 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.7 EEQ34249.1 - 0.047 13.9 0.6 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MDMPI_N PF11716.3 EEQ34249.1 - 0.062 13.7 1.7 0.46 10.8 0.0 2.8 2 1 1 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain Laminin_II PF06009.7 EEQ34249.1 - 0.32 10.7 4.6 0.57 9.9 0.3 2.3 1 1 1 2 2 2 0 Laminin Domain II COG2 PF06148.6 EEQ34249.1 - 0.34 10.7 3.4 1.6 8.6 0.4 2.7 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 EEQ34249.1 - 0.96 8.0 7.5 2.3 6.8 5.3 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EEQ34249.1 - 4.9 6.6 6.4 43 3.6 3.3 2.3 2 0 0 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 EEQ34249.1 - 7.8 6.2 10.8 2.5 7.8 0.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SNF2_N PF00176.18 EEQ34250.1 - 6.9e-55 185.9 0.5 5.6e-54 182.9 0.4 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ34250.1 - 9.6e-16 57.4 3.0 1e-15 57.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF2538 PF10804.3 EEQ34250.1 - 0.086 12.7 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2538) DSPc PF00782.15 EEQ34252.1 - 1.4e-09 37.6 0.2 2.9e-09 36.6 0.1 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EEQ34252.1 - 0.013 14.3 0.1 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Peptidase_M15_2 PF05951.8 EEQ34252.1 - 0.044 13.2 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) zf-C2H2_4 PF13894.1 EEQ34253.1 - 2.1e-08 33.9 7.7 0.01 16.1 0.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ34253.1 - 9.2e-08 31.9 10.3 0.001 19.2 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ34253.1 - 0.32 11.3 17.6 0.31 11.4 0.4 3.9 4 0 0 4 4 4 0 Zinc-finger double domain WD40 PF00400.27 EEQ34255.1 - 3.2e-73 239.2 20.0 3.5e-12 45.6 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEQ34255.1 - 1.3e-10 40.0 2.6 0.00097 17.3 0.0 4.5 4 2 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEQ34255.1 - 9.9e-06 24.5 0.0 0.011 14.5 0.0 3.1 1 1 1 3 3 3 3 Nup133 N terminal like p450 PF00067.17 EEQ34256.1 - 1.2e-73 248.2 0.0 1.3e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 A_deaminase PF00962.17 EEQ34257.1 - 1.5e-28 99.6 0.0 2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase PI-PLC-X PF00388.14 EEQ34257.1 - 0.043 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Urb2 PF10441.4 EEQ34258.1 - 1e-58 198.6 0.0 4.2e-58 196.5 0.0 2.1 1 0 0 1 1 1 1 Urb2/Npa2 family DUF543 PF04418.7 EEQ34259.1 - 3.2e-26 91.0 0.0 3.5e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Metallothio_2 PF01439.13 EEQ34260.1 - 0.24 11.9 22.7 0.12 12.9 3.6 4.0 4 0 0 4 4 4 0 Metallothionein DUF2731 PF10806.3 EEQ34261.1 - 1.8e-05 25.0 0.2 3.6e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 EEQ34261.1 - 0.001 19.3 0.0 0.0037 17.4 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 EEQ34261.1 - 0.018 15.4 0.1 0.026 14.9 0.1 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ34261.1 - 0.078 12.8 0.3 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_31 PF13847.1 EEQ34262.1 - 1.9e-16 60.0 0.0 2.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ34262.1 - 3.9e-15 56.0 0.0 8.8e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ34262.1 - 1.1e-14 54.9 0.0 2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ34262.1 - 1.5e-13 51.0 0.0 3.3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ34262.1 - 1.6e-12 47.4 0.0 2.2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ34262.1 - 1.9e-09 37.7 0.0 3.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ34262.1 - 1.4e-07 30.8 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EEQ34262.1 - 4.3e-07 29.4 0.0 2.1e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.21 EEQ34262.1 - 1.4e-06 27.9 0.1 0.00053 19.5 0.1 3.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase CMAS PF02353.15 EEQ34262.1 - 1.1e-05 24.6 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 EEQ34262.1 - 1.2e-05 24.5 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EEQ34262.1 - 1.5e-05 25.0 0.0 4.8e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ34262.1 - 0.00018 20.5 0.0 0.00044 19.3 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EEQ34262.1 - 0.00076 19.0 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EEQ34262.1 - 0.0018 17.4 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EEQ34262.1 - 0.0033 17.1 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EEQ34262.1 - 0.012 14.7 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.6 EEQ34262.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) FmrO PF07091.6 EEQ34262.1 - 0.034 13.1 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DOT1 PF08123.8 EEQ34262.1 - 0.043 13.1 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 GidB PF02527.10 EEQ34262.1 - 0.058 12.5 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_5 PF01795.14 EEQ34262.1 - 0.1 11.8 0.0 4.5 6.4 0.0 2.1 1 1 1 2 2 2 0 MraW methylase family Methyltransf_7 PF03492.10 EEQ34262.1 - 0.11 11.1 0.0 0.22 10.2 0.0 1.4 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase CDC14 PF08045.6 EEQ34263.1 - 4.9e-100 333.8 0.0 5.7e-100 333.7 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Sugar_tr PF00083.19 EEQ34266.1 - 4.5e-82 276.0 21.9 5.2e-82 275.8 15.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ34266.1 - 8.7e-14 50.9 42.1 1.3e-10 40.5 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_4 PF01063.14 EEQ34267.1 - 3.2e-21 75.8 0.0 3.8e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Cyclin PF08613.6 EEQ34268.1 - 3.3e-14 53.5 0.1 1.1e-13 51.8 0.0 1.9 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEQ34268.1 - 0.003 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cation_efflux PF01545.16 EEQ34269.1 - 2.1e-38 132.0 6.5 1.8e-37 128.9 4.5 1.9 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 EEQ34269.1 - 0.00089 18.3 8.5 0.0016 17.5 5.9 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Aldedh PF00171.17 EEQ34270.1 - 3.5e-143 477.3 0.0 4.2e-143 477.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LysM PF01476.15 EEQ34272.1 - 1.3e-14 53.7 0.0 4.2e-06 26.5 0.0 3.2 3 0 0 3 3 3 2 LysM domain CybS PF05328.7 EEQ34272.1 - 0.098 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 CybS Ribosomal_S13 PF00416.17 EEQ34274.1 - 1.9e-41 140.8 2.7 2.3e-41 140.5 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EEQ34274.1 - 0.011 14.3 0.1 0.013 14.0 0.0 1.3 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EEQ34274.1 - 0.086 12.8 0.3 0.3 11.1 0.0 2.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif Peptidase_S10 PF00450.17 EEQ34275.1 - 1.7e-130 435.9 0.1 2e-130 435.6 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEQ34275.1 - 0.018 14.9 0.0 0.14 12.0 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 EEQ34275.1 - 0.036 14.2 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide SBDS_C PF09377.5 EEQ34276.1 - 1.2e-46 157.4 0.0 1.7e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EEQ34276.1 - 5.1e-23 80.6 0.0 9.4e-23 79.8 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SR-25 PF10500.4 EEQ34276.1 - 0.006 16.0 5.5 0.006 16.0 3.8 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Trypan_PARP PF05887.6 EEQ34276.1 - 1.2 8.8 8.4 7.5 6.3 1.5 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RseA_N PF03872.8 EEQ34277.1 - 0.0014 18.9 2.9 0.0075 16.5 0.0 2.3 2 0 0 2 2 2 1 Anti sigma-E protein RseA, N-terminal domain DUF3043 PF11241.3 EEQ34278.1 - 0.1 12.1 8.9 0.28 10.7 6.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Pyridoxal_deC PF00282.14 EEQ34279.1 - 1.6e-76 257.1 0.0 2.1e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EEQ34279.1 - 9.9e-05 21.2 0.0 0.00016 20.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EEQ34279.1 - 0.047 12.2 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Zn_clus PF00172.13 EEQ34280.1 - 9.6e-07 28.6 11.6 2e-06 27.5 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEQ34280.1 - 1.6e-06 27.0 0.8 2.8e-06 26.1 0.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 EEQ34281.1 - 3.6e-69 233.8 0.0 4.7e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ34281.1 - 3.7e-05 23.4 0.2 0.00018 21.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ34281.1 - 0.09 11.9 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family peroxidase PF00141.18 EEQ34283.1 - 5.2e-48 163.5 0.0 7.3e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Syntaxin PF00804.20 EEQ34284.1 - 0.14 12.3 5.4 0.18 11.9 3.3 1.5 1 1 0 1 1 1 0 Syntaxin TPR_11 PF13414.1 EEQ34285.1 - 4.6e-09 35.8 6.9 8.5e-07 28.5 0.1 2.9 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EEQ34285.1 - 0.00065 19.4 2.5 0.49 10.4 0.0 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ34285.1 - 0.073 12.7 10.9 0.15 11.7 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Zn_clus PF00172.13 EEQ34286.1 - 6.2e-06 26.0 10.3 1.3e-05 24.9 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EEQ34286.1 - 2.9 8.1 10.8 6.1 7.0 7.5 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region p450 PF00067.17 EEQ34287.1 - 6.6e-45 153.4 0.0 8.8e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Herpes_UL87 PF03043.9 EEQ34290.1 - 7.7 4.7 8.9 7.6 4.7 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL87 family PDZ_1 PF12812.2 EEQ34291.1 - 2.4e-53 177.9 0.0 3.8e-34 116.4 0.0 3.1 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.1 EEQ34291.1 - 2.7e-13 49.5 0.0 0.00034 20.4 0.0 4.0 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 EEQ34291.1 - 8.5e-09 35.4 0.0 0.00035 20.6 0.0 3.7 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypsin_2 PF13365.1 EEQ34291.1 - 1.1e-05 25.3 0.0 4e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Trypsin-like peptidase domain Tricorn_PDZ PF14685.1 EEQ34291.1 - 0.00019 21.1 0.1 1.1 9.1 0.0 3.9 5 0 0 5 5 5 2 Tricorn protease PDZ domain Trypsin PF00089.21 EEQ34291.1 - 0.012 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Trypsin DUF31 PF01732.11 EEQ34291.1 - 0.12 11.7 0.4 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 EEQ34291.1 - 0.24 10.7 0.2 0.5 9.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease INCENP_ARK-bind PF03941.10 EEQ34292.1 - 1.1e-18 66.7 0.4 1.1e-18 66.7 0.2 2.3 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region DNA_topoisoIV PF00521.15 EEQ34293.1 - 2.5e-132 441.7 0.1 5.7e-132 440.5 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EEQ34293.1 - 7.6e-36 122.9 3.1 2.2e-35 121.4 2.1 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EEQ34293.1 - 7e-13 48.4 0.1 3.8e-12 46.0 0.0 2.4 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EEQ34293.1 - 5.2e-11 42.2 0.0 1.7e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reticulon PF02453.12 EEQ34295.1 - 1e-34 119.5 4.4 2e-34 118.6 3.1 1.4 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.6 EEQ34295.1 - 1.5 7.5 6.1 4.8 5.8 2.2 2.0 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Acyl-CoA_dh_1 PF00441.19 EEQ34296.1 - 4.1e-26 91.8 2.5 7e-26 91.1 1.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ34296.1 - 1.3e-19 70.7 0.5 2.9e-17 63.2 0.3 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEQ34296.1 - 3.5e-14 53.2 0.8 7.8e-14 52.0 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RabGAP-TBC PF00566.13 EEQ34297.1 - 4.6e-48 163.5 0.3 3e-47 160.8 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3584 PF12128.3 EEQ34297.1 - 0.93 6.7 22.1 1.6 5.9 15.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 EEQ34297.1 - 1.8 8.3 9.1 0.12 12.1 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.14 EEQ34297.1 - 4 5.0 32.3 0.0057 14.4 14.6 1.9 3 0 0 3 3 3 0 Myosin tail MFS_1 PF07690.11 EEQ34298.1 - 1.4e-27 96.3 37.2 4.3e-27 94.7 24.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ34298.1 - 0.00034 18.9 1.8 0.00045 18.5 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Med4 PF10018.4 EEQ34299.1 - 1.3e-32 112.7 1.0 2.6e-32 111.7 0.7 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 EF-hand_7 PF13499.1 EEQ34300.1 - 1e-29 102.4 4.8 2.8e-13 49.7 0.2 3.1 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EEQ34300.1 - 2.1e-26 89.1 9.6 3.4e-08 32.2 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EEQ34300.1 - 8.5e-25 84.3 2.0 2.7e-06 26.7 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EEQ34300.1 - 4.5e-18 63.6 15.4 1.3e-05 24.2 0.0 4.8 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.1 EEQ34300.1 - 5.4e-15 54.7 15.0 3.2e-06 26.6 1.0 4.3 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EEQ34300.1 - 3.9e-09 36.1 4.7 0.00093 18.9 0.1 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EEQ34300.1 - 0.00026 20.8 0.3 0.36 10.7 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.1 EEQ34300.1 - 0.0033 17.0 1.0 1.5 8.5 0.0 3.9 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 EEQ34300.1 - 0.0064 16.4 0.5 0.45 10.5 0.1 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 EEQ34300.1 - 0.014 14.1 0.5 1 7.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Mad3_BUB1_II PF08171.6 EEQ34300.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 EF-hand_2 PF09068.6 EEQ34300.1 - 0.087 12.8 0.0 14 5.7 0.0 3.0 3 1 0 3 3 3 0 EF hand EMP70 PF02990.11 EEQ34301.1 - 6.2e-182 605.6 3.5 6.2e-182 605.6 2.4 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 bZIP_1 PF00170.16 EEQ34302.1 - 0.36 10.8 4.9 0.74 9.8 3.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor FKBP_C PF00254.23 EEQ34303.1 - 4.5e-06 26.5 0.0 6.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF953 PF06110.6 EEQ34303.1 - 0.0074 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) zf-C2H2_4 PF13894.1 EEQ34303.1 - 0.61 10.5 9.3 2 8.9 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ34303.1 - 1 9.5 6.8 0.84 9.8 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF3652 PF12372.3 EEQ34309.1 - 0.031 13.8 0.3 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 Huntingtin protein region Pyr_redox_3 PF13738.1 EEQ34310.1 - 2.2e-17 63.8 0.0 6e-17 62.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ34310.1 - 1.9e-15 56.0 0.0 7.6e-15 54.0 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EEQ34310.1 - 5.5e-11 42.7 0.0 9.8e-10 38.6 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ34310.1 - 2.8e-10 39.6 0.0 3.9e-08 32.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEQ34310.1 - 1.7e-07 31.1 1.8 2.6e-06 27.3 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEQ34310.1 - 5.8e-07 29.8 5.5 0.0033 17.7 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ34310.1 - 2e-05 23.7 0.1 0.00062 18.7 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEQ34310.1 - 9.4e-05 22.2 1.8 0.023 14.4 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EEQ34310.1 - 0.0013 18.9 0.0 0.031 14.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EEQ34310.1 - 0.0015 18.1 0.8 0.35 10.4 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EEQ34310.1 - 0.0027 17.3 0.1 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EEQ34310.1 - 0.0099 14.9 0.0 2.6 7.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 EEQ34310.1 - 0.01 15.9 0.2 0.47 10.5 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EEQ34310.1 - 0.033 13.0 0.3 0.033 13.0 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EEQ34310.1 - 0.066 11.6 1.6 1.8 6.9 0.1 2.8 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 EEQ34310.1 - 0.16 11.1 0.0 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EEQ34310.1 - 3.3 6.4 4.4 1.2 7.8 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Sas10_Utp3 PF04000.10 EEQ34312.1 - 4.8e-16 58.7 0.9 4.8e-16 58.7 0.7 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Hid1 PF12722.2 EEQ34312.1 - 5.9 4.4 6.8 7.8 4.0 4.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MFS_1 PF07690.11 EEQ34313.1 - 2.3e-12 46.3 36.8 2.9e-12 45.9 24.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEQ34313.1 - 6.4e-08 32.2 4.9 6.4e-08 32.2 3.4 3.0 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 CFEM PF05730.6 EEQ34314.1 - 1.6e-12 47.0 2.9 2.5e-12 46.4 2.0 1.3 1 0 0 1 1 1 1 CFEM domain UQ_con PF00179.21 EEQ34315.1 - 1e-39 135.1 0.0 1.1e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pox_A14 PF05767.7 EEQ34316.1 - 3.1 7.8 9.7 3.4 7.6 0.6 3.1 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 AA_permease PF00324.16 EEQ34317.1 - 2.3e-32 112.0 7.1 2e-31 108.8 4.9 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ34317.1 - 1.2e-12 47.1 2.2 1.7e-12 46.6 1.5 1.2 1 1 0 1 1 1 1 Amino acid permease 7tm_1 PF00001.16 EEQ34317.1 - 0.017 14.3 0.8 0.17 11.0 0.0 2.4 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) AA_permease PF00324.16 EEQ34318.1 - 1.8e-22 79.3 9.4 2.1e-22 79.1 6.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ34318.1 - 1.7e-09 36.7 7.4 2.1e-09 36.4 5.2 1.0 1 0 0 1 1 1 1 Amino acid permease GAF_3 PF13492.1 EEQ34320.1 - 0.015 15.4 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 GAF domain LtrA PF06772.6 EEQ34321.1 - 1.1e-12 47.5 36.6 1.2e-12 47.4 13.7 3.0 2 1 1 3 3 3 2 Bacterial low temperature requirement A protein (LtrA) DUF2976 PF11190.3 EEQ34321.1 - 1.8 8.1 14.2 0.1 12.1 0.5 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Mito_carr PF00153.22 EEQ34322.1 - 1.5e-61 204.1 4.6 3.3e-21 74.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIIC_delta PF12657.2 EEQ34323.1 - 7.6e-45 152.7 1.4 1.2e-44 152.0 1.0 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EEQ34323.1 - 6.8e-08 32.3 0.1 1.7e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex MFS_1 PF07690.11 EEQ34324.1 - 3.4e-34 118.1 40.9 3.4e-34 118.1 28.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ34324.1 - 1.3e-15 56.7 22.2 1.6e-15 56.3 15.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ34324.1 - 2.6e-11 42.7 5.9 2.6e-11 42.7 4.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter PS-DH PF14765.1 EEQ34325.1 - 5.7e-58 196.4 0.2 9e-58 195.7 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EEQ34325.1 - 2.7e-11 43.4 0.0 8.1e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ34325.1 - 6.4e-11 42.1 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Glyco_trans_1_4 PF13692.1 EEQ34326.1 - 4.5e-26 91.6 0.0 1.8e-25 89.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEQ34326.1 - 1.4e-07 31.7 3.4 2.4e-07 31.0 2.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EEQ34326.1 - 2.4e-05 24.5 0.0 4.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EEQ34326.1 - 0.00021 20.7 0.0 0.001 18.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Cation_efflux PF01545.16 EEQ34327.1 - 2.2e-53 181.2 14.3 2.2e-53 181.2 9.9 3.0 3 0 0 3 3 3 2 Cation efflux family UQ_con PF00179.21 EEQ34328.1 - 1.2e-51 173.7 0.0 1.4e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ34328.1 - 3.3e-06 26.8 0.0 3.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ34328.1 - 0.061 13.2 0.1 0.093 12.6 0.0 1.5 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.18 EEQ34329.1 - 1.6e-95 319.0 1.1 2.2e-95 318.5 0.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEQ34329.1 - 9.6e-38 128.3 0.7 9.6e-38 128.3 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEQ34329.1 - 0.00014 21.4 0.6 0.00029 20.4 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EEQ34329.1 - 0.054 13.1 3.0 3 7.5 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Kinesin PF00225.18 EEQ34330.1 - 1.6e-112 375.5 0.4 4.2e-112 374.1 0.2 1.8 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_C1_2 PF03051.10 EEQ34331.1 - 1.6e-160 534.3 0.0 1.9e-160 534.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EEQ34331.1 - 8.5e-10 38.8 0.1 4e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 Papain family cysteine protease UPF0160 PF03690.8 EEQ34332.1 - 7e-113 377.2 0.0 8e-113 377.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Rib PF08428.5 EEQ34332.1 - 0.071 12.8 0.0 0.29 10.9 0.0 2.0 3 0 0 3 3 3 0 Rib/alpha-like repeat 5_nucleotid_C PF02872.13 EEQ34333.1 - 1.3e-34 119.4 0.0 3.3e-34 118.1 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EEQ34333.1 - 3.7e-08 32.9 0.0 5.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ34333.1 - 0.03 14.1 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 EEQ34334.1 - 3e-05 23.2 0.0 6.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ34334.1 - 0.00046 20.0 1.3 0.00056 19.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ34334.1 - 0.00064 18.8 0.3 0.0016 17.5 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_trans_1_2 PF13524.1 EEQ34334.1 - 0.012 15.8 3.2 0.065 13.5 0.8 2.5 2 0 0 2 2 2 0 Glycosyl transferases group 1 HSDR_N_2 PF13588.1 EEQ34334.1 - 0.033 13.9 0.0 0.1 12.4 0.0 1.8 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) cwf21 PF08312.7 EEQ34334.1 - 0.039 13.7 0.2 0.039 13.7 0.1 2.8 3 0 0 3 3 3 0 cwf21 domain RIO1 PF01163.17 EEQ34334.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Peptidase_M35 PF02102.10 EEQ34336.1 - 7.9e-94 314.2 10.4 1.2e-93 313.6 7.2 1.3 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EEQ34336.1 - 2.3e-07 31.4 0.2 5.3e-07 30.2 0.2 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EEQ34336.1 - 1.2e-05 24.8 3.8 0.00013 21.4 2.7 2.0 1 1 0 1 1 1 1 Putative peptidase family His_Phos_1 PF00300.17 EEQ34337.1 - 6e-08 32.9 0.3 7.3e-05 22.9 0.0 2.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) CorA PF01544.13 EEQ34338.1 - 0.0011 18.0 0.6 0.0017 17.4 0.4 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3430 PF11912.3 EEQ34339.1 - 0.00095 19.0 0.0 0.0011 18.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) IncA PF04156.9 EEQ34340.1 - 3 7.4 4.7 5.8 6.4 3.2 1.4 1 0 0 1 1 1 0 IncA protein Ank_2 PF12796.2 EEQ34342.1 - 1.3e-24 86.2 0.0 7e-14 51.9 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ34342.1 - 3e-20 70.9 1.8 1.4e-06 27.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EEQ34342.1 - 1.6e-17 63.4 0.1 0.00013 22.3 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ34342.1 - 2.3e-17 62.6 4.5 1.7e-06 28.0 0.0 4.1 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ34342.1 - 2.3e-14 52.0 0.9 0.0016 18.4 0.0 5.2 4 2 2 6 6 6 4 Ankyrin repeat DUF1843 PF08898.5 EEQ34342.1 - 0.0047 16.9 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) DUF1110 PF06533.7 EEQ34342.1 - 0.055 13.2 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) TPR_12 PF13424.1 EEQ34343.1 - 1e-20 73.4 9.1 6e-06 26.1 1.2 4.9 3 2 2 5 5 5 5 Tetratricopeptide repeat NB-ARC PF00931.17 EEQ34343.1 - 1.5e-11 43.6 0.0 2.8e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 EEQ34343.1 - 3.6e-11 42.5 4.2 0.00064 19.3 0.0 4.5 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 EEQ34343.1 - 3.4e-07 29.6 7.2 0.097 12.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ34343.1 - 3.4e-06 26.8 1.4 0.00035 20.3 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ34343.1 - 7.6e-05 23.2 1.1 1.1 10.0 0.0 4.5 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ34343.1 - 0.00032 20.1 5.0 0.29 10.8 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ34343.1 - 0.00045 20.6 0.0 53 4.8 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF676 PF05057.9 EEQ34343.1 - 0.0098 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 EEQ34343.1 - 0.011 15.7 0.0 0.045 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain Abhydrolase_6 PF12697.2 EEQ34343.1 - 0.042 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_22 PF13401.1 EEQ34343.1 - 0.062 13.4 0.1 0.91 9.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF1029 PF06269.7 EEQ34343.1 - 0.19 11.7 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) CorA PF01544.13 EEQ34344.1 - 6.1e-10 38.6 1.6 1.2e-09 37.6 1.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2605 PF10792.4 EEQ34344.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Amidase PF01425.16 EEQ34345.1 - 2.8e-23 82.4 0.1 3.9e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF3262 PF11660.3 EEQ34349.1 - 0.034 14.2 0.6 0.034 14.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) Ribosomal_S13 PF00416.17 EEQ34350.1 - 4.2e-22 78.6 0.3 4.7e-22 78.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 WD40 PF00400.27 EEQ34351.1 - 3.8e-28 96.3 20.5 2e-07 30.6 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 EEQ34351.1 - 1.3e-19 69.9 0.0 2.5e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain ALAD PF00490.16 EEQ34353.1 - 4.9e-101 337.8 0.0 5.6e-101 337.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Methyltransf_12 PF08242.7 EEQ34354.1 - 0.00018 21.9 0.0 0.00044 20.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ34354.1 - 0.00032 20.3 0.0 0.002 17.7 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ34354.1 - 0.0013 19.1 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ34354.1 - 0.0015 18.2 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ34354.1 - 0.067 13.5 0.0 0.15 12.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ycf1 PF05758.7 EEQ34354.1 - 0.14 9.8 0.0 0.2 9.3 0.0 1.2 1 0 0 1 1 1 0 Ycf1 AMP-binding PF00501.23 EEQ34355.1 - 7.5e-77 258.4 0.0 9.1e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ34355.1 - 2.3e-09 38.0 0.0 6.3e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zw10 PF06248.8 EEQ34356.1 - 3e-20 71.9 0.7 6.1e-19 67.6 0.2 2.4 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EEQ34356.1 - 2.9e-05 23.3 0.1 2.9e-05 23.3 0.1 2.9 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Peptidase_M16_C PF05193.16 EEQ34357.1 - 2.9e-17 62.9 0.0 2.1e-13 50.3 0.0 3.0 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEQ34357.1 - 0.00081 19.1 0.0 0.0026 17.5 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) RQC PF09382.5 EEQ34357.1 - 0.0085 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 RQC domain Vfa1 PF08432.5 EEQ34357.1 - 0.43 10.5 11.6 0.53 10.2 6.3 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ank_2 PF12796.2 EEQ34358.1 - 2e-48 162.6 0.3 1.9e-13 50.5 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ34358.1 - 2e-37 125.1 1.0 0.00013 21.6 0.0 10.5 9 1 1 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 EEQ34358.1 - 3.2e-35 119.8 0.2 3.9e-07 30.3 0.0 7.5 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ34358.1 - 6.9e-29 97.0 0.0 0.034 14.3 0.0 10.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 EEQ34358.1 - 1.7e-25 88.4 1.8 0.00061 19.9 0.0 8.0 5 2 4 9 9 9 6 Ankyrin repeats (many copies) NACHT PF05729.7 EEQ34358.1 - 0.0078 15.8 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Peptidase_M48 PF01435.13 EEQ34359.1 - 3.2e-50 170.7 0.0 4.5e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EEQ34359.1 - 0.0057 15.6 0.5 0.028 13.4 0.1 2.0 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.1 EEQ34359.1 - 0.0094 15.2 1.0 0.022 14.0 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) DUF2201_N PF13203.1 EEQ34359.1 - 0.19 10.8 0.1 0.35 9.9 0.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain RNA_polI_A14 PF08203.6 EEQ34360.1 - 0.0046 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Yeast RNA polymerase I subunit RPA14 RHIM PF12721.2 EEQ34360.1 - 0.18 12.2 0.5 0.38 11.2 0.1 1.7 2 0 0 2 2 2 0 RIP homotypic interaction motif Adeno_VII PF03228.9 EEQ34360.1 - 0.54 10.8 5.6 1 9.9 3.9 1.4 1 0 0 1 1 1 0 Adenoviral core protein VII Ribosomal_L34 PF00468.12 EEQ34361.1 - 3.3e-15 55.4 9.8 5.2e-15 54.8 6.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 GTP_EFTU PF00009.22 EEQ34362.1 - 3.9e-38 130.7 0.0 6.2e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EEQ34362.1 - 4.4e-36 122.7 0.1 9e-36 121.8 0.1 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EEQ34362.1 - 1.2e-11 44.5 0.3 2.5e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ34362.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEQ34362.1 - 0.13 12.1 0.0 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Dynamin family WD40 PF00400.27 EEQ34363.1 - 1.5e-13 50.0 0.0 0.00022 20.9 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat HSA PF07529.8 EEQ34364.1 - 1.6e-21 75.8 2.4 1.6e-21 75.8 1.7 3.1 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 EEQ34364.1 - 1.9e-15 56.7 0.2 1.9e-15 56.7 0.1 3.4 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ34364.1 - 0.00067 19.6 0.1 0.0019 18.2 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain AMP-binding PF00501.23 EEQ34365.1 - 1.8e-29 102.4 0.4 1.2e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEQ34365.1 - 3.1e-25 88.6 0.5 4.1e-12 45.5 0.2 3.3 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EEQ34365.1 - 8.9e-07 29.0 0.0 2.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ABC_tran PF00005.22 EEQ34366.1 - 1.3e-46 158.2 0.0 5.9e-27 94.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ34366.1 - 7.5e-30 104.2 41.1 3.4e-28 98.8 12.0 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEQ34366.1 - 2.9e-18 66.8 0.3 3.7e-05 23.8 0.0 4.5 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EEQ34366.1 - 1.3e-11 44.1 1.9 4.2e-05 22.8 0.1 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEQ34366.1 - 7.5e-07 29.3 0.2 0.0065 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEQ34366.1 - 2.2e-06 27.1 0.1 0.032 13.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EEQ34366.1 - 9.1e-05 21.6 0.4 0.3 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ34366.1 - 0.00015 22.5 0.4 1 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ34366.1 - 0.00025 20.9 0.0 0.66 9.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EEQ34366.1 - 0.00034 21.0 0.2 0.79 10.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EEQ34366.1 - 0.00039 20.7 0.2 1.4 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ34366.1 - 0.00089 18.7 0.7 0.65 9.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EEQ34366.1 - 0.0011 18.4 0.1 0.72 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 EEQ34366.1 - 0.0011 19.0 0.9 1.8 8.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 EEQ34366.1 - 0.0021 17.7 1.2 1.6 8.4 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEQ34366.1 - 0.0042 16.9 0.0 0.42 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EEQ34366.1 - 0.0043 15.6 1.1 0.22 10.0 0.0 2.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 EEQ34366.1 - 0.0066 15.5 0.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 EEQ34366.1 - 0.011 14.6 0.1 0.2 10.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 EEQ34366.1 - 0.019 14.7 0.7 0.98 9.2 0.0 2.4 2 0 0 2 2 2 0 Dynamin family ArgK PF03308.11 EEQ34366.1 - 0.041 12.6 0.3 0.3 9.8 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_23 PF13476.1 EEQ34366.1 - 0.047 14.0 0.5 12 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EEQ34366.1 - 0.051 13.2 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.12 EEQ34366.1 - 0.052 13.0 0.6 0.95 8.9 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EEQ34366.1 - 0.16 11.6 0.4 8.8 5.9 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase ATP-synt_ab PF00006.20 EEQ34366.1 - 0.17 11.3 0.6 9.3 5.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EEQ34366.1 - 0.69 9.6 2.8 6 6.6 0.6 3.0 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) SNF2_N PF00176.18 EEQ34367.1 - 1.1e-06 27.7 0.0 2.7e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ34367.1 - 0.014 15.2 2.5 0.21 11.4 0.0 3.2 3 1 1 4 4 4 0 Helicase conserved C-terminal domain Daxx PF03344.10 EEQ34367.1 - 6.9 5.0 11.3 25 3.1 6.1 2.1 2 0 0 2 2 2 0 Daxx Family G-patch_2 PF12656.2 EEQ34368.1 - 3.2e-27 94.1 1.8 6.9e-27 93.1 0.0 2.7 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 EEQ34368.1 - 0.00017 21.2 0.5 0.00045 19.9 0.3 1.8 1 0 0 1 1 1 1 G-patch domain WD40 PF00400.27 EEQ34369.1 - 5.2e-78 254.4 30.1 2.7e-09 36.5 0.2 13.5 13 2 0 13 13 13 11 WD domain, G-beta repeat Utp13 PF08625.6 EEQ34369.1 - 2.1e-44 150.5 0.0 3.2e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EEQ34369.1 - 1.8e-08 32.9 9.7 0.13 10.4 1.3 4.8 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEQ34369.1 - 1.2e-05 24.2 4.1 0.017 13.8 0.0 5.0 5 1 0 5 5 5 2 Nup133 N terminal like UCH PF00443.24 EEQ34371.1 - 1.4e-22 80.1 0.0 3.8e-21 75.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEQ34371.1 - 7.3e-12 45.2 0.2 1.3e-11 44.4 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EEQ34371.1 - 2.9e-05 23.6 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TLD PF07534.11 EEQ34372.1 - 2.8e-09 37.1 0.2 5.4e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 TLD LRAT PF04970.8 EEQ34373.1 - 0.0048 16.8 0.1 0.014 15.3 0.1 1.7 2 0 0 2 2 2 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.9 EEQ34373.1 - 0.0078 15.9 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRRC37AB_C PF14914.1 EEQ34373.1 - 0.0093 15.4 1.9 0.015 14.7 1.3 1.4 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain Proteasome PF00227.21 EEQ34374.1 - 1.7e-29 102.4 0.0 2.1e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EEQ34375.1 - 2.7e-29 99.9 16.0 9.8e-08 31.6 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EEQ34375.1 - 0.00015 20.0 1.3 1.2 7.1 0.3 3.4 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEQ34375.1 - 0.0024 16.6 0.1 0.81 8.3 0.0 2.7 1 1 0 2 2 2 2 Nup133 N terminal like zf-RING_2 PF13639.1 EEQ34376.1 - 5.4e-10 38.9 8.1 5.4e-10 38.9 5.6 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ34376.1 - 9.8e-09 34.7 4.8 9.8e-09 34.7 3.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ34376.1 - 1.2e-08 34.4 7.4 1.2e-08 34.4 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ34376.1 - 1.4e-08 34.6 8.3 1.4e-08 34.6 5.8 2.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ34376.1 - 3e-07 30.0 7.4 3e-07 30.0 5.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEQ34376.1 - 5.8e-07 29.2 10.4 5.8e-07 29.2 7.2 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ34376.1 - 1.8e-05 24.3 2.8 4e-05 23.2 1.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger DZR PF12773.2 EEQ34376.1 - 0.018 14.8 14.0 0.21 11.4 0.8 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-Apc11 PF12861.2 EEQ34376.1 - 0.029 14.1 2.8 0.029 14.1 2.0 1.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEQ34376.1 - 0.12 12.0 16.1 0.12 11.9 4.9 2.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EEQ34376.1 - 0.94 9.6 12.7 0.15 12.2 4.4 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EEQ34376.1 - 2.3 8.0 8.7 0.14 11.9 2.2 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein BUD22 PF09073.5 EEQ34376.1 - 6.9 5.6 14.0 14 4.6 9.7 1.6 1 0 0 1 1 1 0 BUD22 2OG-FeII_Oxy_3 PF13640.1 EEQ34377.1 - 0.0019 18.6 0.0 0.0037 17.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2527 PF10736.4 EEQ34377.1 - 0.039 13.5 0.1 0.088 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) CHCH PF06747.8 EEQ34378.1 - 1.1e-05 25.2 3.0 1.1e-05 25.2 2.1 1.8 1 1 1 2 2 2 1 CHCH domain DUF1903 PF08991.5 EEQ34378.1 - 0.00068 19.7 2.3 0.001 19.1 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 EEQ34378.1 - 0.012 15.4 4.2 0.036 13.9 2.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EEQ34378.1 - 0.53 10.0 4.4 1.6 8.5 0.4 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EEQ34378.1 - 0.69 10.0 4.8 2 8.5 2.4 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 NatB_MDM20 PF09797.4 EEQ34379.1 - 1e-88 297.5 0.4 1.8e-88 296.7 0.3 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EEQ34379.1 - 2.6e-06 27.6 7.3 0.024 14.9 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ34379.1 - 9.4e-05 22.9 6.7 0.47 11.2 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ34379.1 - 0.0046 17.4 6.1 61 4.6 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PIN PF01850.16 EEQ34379.1 - 0.068 13.5 0.5 0.34 11.2 0.2 2.2 2 0 0 2 2 2 0 PIN domain Proteasome PF00227.21 EEQ34380.1 - 2.7e-41 140.9 0.0 3.2e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 EEQ34381.1 - 3.4e-24 84.5 0.9 9.2e-24 83.1 0.0 2.2 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EEQ34381.1 - 5.1e-07 29.6 0.4 2.8e-06 27.2 0.0 2.4 3 0 0 3 3 3 1 UBX domain RBD PF02196.10 EEQ34381.1 - 0.0016 18.1 0.0 0.0079 15.9 0.0 2.0 2 0 0 2 2 2 1 Raf-like Ras-binding domain Ribosomal_L36e PF01158.13 EEQ34382.1 - 3.6e-38 129.4 7.2 4.1e-38 129.3 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EEQ34382.1 - 0.13 11.3 0.4 0.14 11.2 0.3 1.1 1 0 0 1 1 1 0 LemA family Syntaxin-6_N PF09177.6 EEQ34382.1 - 0.16 12.3 0.9 7 7.1 0.1 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal MRP-L28 PF09812.4 EEQ34382.1 - 0.24 11.2 2.6 0.27 11.0 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 PRTase_3 PF15610.1 EEQ34383.1 - 0.039 12.8 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like HATPase_c PF02518.21 EEQ34384.1 - 4.8e-19 68.1 0.0 9e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEQ34384.1 - 2.9e-14 53.0 0.5 1.6e-08 34.5 0.1 3.4 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EEQ34384.1 - 2.3e-05 24.3 0.0 7.8e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EEQ34384.1 - 0.051 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase M20_dimer PF07687.9 EEQ34385.1 - 1.4e-20 73.0 0.0 4.2e-20 71.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EEQ34385.1 - 5.2e-18 65.2 2.5 1.6e-17 63.6 1.7 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EEQ34385.1 - 0.00035 19.4 0.0 0.006 15.3 0.0 2.3 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF373 PF04123.8 EEQ34385.1 - 0.021 13.8 0.5 0.021 13.8 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Glyco_hydro_47 PF01532.15 EEQ34386.1 - 3.9e-160 533.4 0.0 5.2e-160 533.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.24 EEQ34387.1 - 5.3e-43 146.3 0.0 8.9e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ34387.1 - 3.2e-07 30.5 0.0 5.7e-06 26.4 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.9 EEQ34387.1 - 1.7e-06 27.8 0.0 4.2e-05 23.2 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ34387.1 - 1.9e-06 27.9 0.0 6.6e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EEQ34387.1 - 2.4e-06 27.6 0.0 0.00088 19.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EEQ34387.1 - 7.8e-06 25.1 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EEQ34387.1 - 0.00032 19.6 0.0 0.00074 18.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EEQ34387.1 - 0.00037 21.3 0.4 0.0014 19.4 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EEQ34387.1 - 0.00046 19.8 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EEQ34387.1 - 0.0012 19.1 0.2 0.0074 16.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEQ34387.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EEQ34387.1 - 0.0015 17.3 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEQ34387.1 - 0.0017 18.2 0.0 0.0055 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EEQ34387.1 - 0.0031 16.9 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEQ34387.1 - 0.004 16.3 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EEQ34387.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EEQ34387.1 - 0.007 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEQ34387.1 - 0.0082 15.6 0.0 0.029 13.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EEQ34387.1 - 0.0088 15.4 0.1 0.046 13.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEQ34387.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase DUF4200 PF13863.1 EEQ34387.1 - 0.011 15.6 0.4 0.032 14.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_24 PF13479.1 EEQ34387.1 - 0.019 14.5 0.1 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EEQ34387.1 - 0.021 14.6 0.0 0.055 13.2 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EEQ34387.1 - 0.027 13.5 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 EEQ34387.1 - 0.028 14.3 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEQ34387.1 - 0.03 14.0 0.1 0.14 11.8 0.0 2.2 2 1 0 2 2 1 0 Archaeal ATPase UPF0079 PF02367.12 EEQ34387.1 - 0.033 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EEQ34387.1 - 0.036 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 EEQ34387.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EEQ34387.1 - 0.053 13.1 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.1 EEQ34387.1 - 0.07 12.6 0.2 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EEQ34387.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 EEQ34387.1 - 0.11 12.7 2.6 2.7 8.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain E1-E2_ATPase PF00122.15 EEQ34388.1 - 1.5e-49 168.1 3.2 3.5e-49 166.9 2.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ34388.1 - 3.8e-44 150.3 3.3 3.8e-44 150.3 2.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ34388.1 - 5e-32 112.0 0.0 1.5e-31 110.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ34388.1 - 6e-20 70.9 0.0 1.2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ34388.1 - 1.1e-13 51.7 0.0 2.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ34388.1 - 7.8e-11 41.2 0.0 1.8e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEQ34388.1 - 0.00014 21.5 0.1 0.0004 20.0 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MIP-T3 PF10243.4 EEQ34388.1 - 1.3 7.3 4.3 1.9 6.8 3.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Enolase_C PF00113.17 EEQ34389.1 - 2.1e-153 509.5 0.0 3e-153 509.0 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EEQ34389.1 - 6.8e-57 191.0 0.6 1.1e-56 190.3 0.4 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 EEQ34389.1 - 0.064 13.7 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 EEQ34389.1 - 0.085 12.8 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like eIF3_subunit PF08597.5 EEQ34390.1 - 8.3e-47 159.8 21.5 1.9e-44 152.1 8.9 2.0 1 1 1 2 2 2 2 Translation initiation factor eIF3 subunit HMG_box PF00505.14 EEQ34390.1 - 0.05 13.8 1.7 0.14 12.4 1.2 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box FAM176 PF14851.1 EEQ34390.1 - 8.7 6.0 7.7 4.1 7.0 2.4 2.2 2 0 0 2 2 2 0 FAM176 family 14-3-3 PF00244.15 EEQ34391.1 - 1.2e-113 378.0 2.0 1.7e-113 377.5 1.4 1.2 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 EEQ34391.1 - 0.04 13.3 0.2 0.079 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HisKA PF00512.20 EEQ34391.1 - 0.053 13.5 0.3 18 5.3 0.0 3.1 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain TPR_12 PF13424.1 EEQ34391.1 - 0.24 11.3 4.1 12 5.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.20 EEQ34392.1 - 7.5e-16 58.4 0.0 1.4e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ34392.1 - 6.8e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ34392.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family E1-E2_ATPase PF00122.15 EEQ34393.1 - 5.3e-64 215.3 5.3 5.3e-64 215.3 3.7 2.7 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ34393.1 - 5e-45 153.2 6.6 5e-45 153.2 4.6 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ34393.1 - 4.5e-32 112.2 0.0 3.4e-31 109.3 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ34393.1 - 2e-19 69.3 0.0 4e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEQ34393.1 - 2e-19 68.7 0.0 6.5e-19 67.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEQ34393.1 - 1.8e-15 57.6 0.0 1e-14 55.1 0.0 2.4 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ34393.1 - 7.8e-08 32.2 1.2 9e-06 25.4 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Proteasome_A_N PF10584.4 EEQ34393.1 - 0.013 14.7 0.5 0.13 11.6 0.0 2.4 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature HAD_2 PF13419.1 EEQ34393.1 - 0.044 14.0 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Peptidase_S8 PF00082.17 EEQ34394.1 - 6.1e-43 146.9 12.8 6.1e-43 146.9 8.9 1.4 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ34394.1 - 1.3e-15 57.7 0.3 2.4e-15 56.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 MBOAT_2 PF13813.1 EEQ34396.1 - 5.1e-21 74.5 4.1 1.1e-20 73.4 2.8 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Macoilin PF09726.4 EEQ34397.1 - 4.8 5.3 8.7 6.1 5.0 6.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DnaJ PF00226.26 EEQ34398.1 - 2.6e-10 39.8 0.4 4.5e-10 39.1 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EEQ34398.1 - 0.0046 17.0 0.4 0.0076 16.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF456) MFS_1 PF07690.11 EEQ34399.1 - 8.5e-40 136.5 51.1 7e-39 133.5 35.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ34399.1 - 3.3e-08 32.1 22.9 3.3e-08 32.1 15.8 1.8 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PMM PF03332.8 EEQ34400.1 - 4.8e-80 268.2 1.5 1.3e-44 152.4 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EEQ34400.1 - 0.0087 15.6 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ34400.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1640 PF07798.6 EEQ34401.1 - 3.7e-64 216.0 5.4 4.6e-64 215.6 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) G-alpha PF00503.15 EEQ34401.1 - 0.016 13.9 0.8 0.026 13.2 0.5 1.3 1 0 0 1 1 1 0 G-protein alpha subunit VitD-bind_III PF09164.5 EEQ34401.1 - 0.085 12.4 0.1 0.26 10.9 0.1 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Trypsin_2 PF13365.1 EEQ34402.1 - 4.7e-15 55.6 0.0 7.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EEQ34402.1 - 0.00048 19.7 0.0 0.0013 18.4 0.0 1.6 1 1 0 1 1 1 1 Trypsin Peptidase_C4 PF00863.14 EEQ34402.1 - 0.00099 18.1 0.0 0.018 14.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase family C4 Peptidase_S32 PF05579.8 EEQ34402.1 - 0.15 11.0 0.0 0.81 8.6 0.0 1.9 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 DUF3812 PF12757.2 EEQ34403.1 - 2.1e-34 118.2 2.5 2.1e-34 118.2 1.8 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3812) Pal1 PF08316.6 EEQ34403.1 - 2 8.8 6.6 1.3 9.4 0.1 3.1 3 0 0 3 3 3 0 Pal1 cell morphology protein MFS_1 PF07690.11 EEQ34404.1 - 2e-16 59.6 35.2 3.3e-16 58.9 24.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ34404.1 - 0.00032 19.4 11.9 0.00032 19.4 8.2 2.4 1 1 1 3 3 3 1 Sugar (and other) transporter HlyIII PF03006.15 EEQ34404.1 - 0.0016 17.8 12.6 0.018 14.4 2.6 3.5 2 1 1 3 3 3 2 Haemolysin-III related DUF373 PF04123.8 EEQ34404.1 - 0.36 9.8 3.9 0.25 10.3 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Pkinase PF00069.20 EEQ34405.1 - 6.2e-49 166.4 0.0 6.2e-49 166.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34405.1 - 9.7e-26 90.3 0.0 1.6e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ34405.1 - 7.5e-10 38.2 0.0 1.2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ34405.1 - 0.0011 18.0 0.9 0.0066 15.5 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ34405.1 - 0.076 12.7 5.3 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ34405.1 - 0.29 10.6 0.5 0.6 9.6 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Prenyltrans PF00432.16 EEQ34406.1 - 1.7e-30 104.2 10.1 1.2e-07 31.1 0.0 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEQ34406.1 - 2.9e-25 88.8 0.0 5.6e-19 68.6 0.0 3.7 3 1 1 4 4 4 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEQ34406.1 - 6.4e-08 32.5 0.0 0.00017 21.5 0.0 3.8 2 1 2 4 4 4 2 Prenyltransferase-like Ilm1 PF10311.4 EEQ34407.1 - 1.4e-19 70.1 0.0 4.3e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Phosphoprotein PF00922.12 EEQ34407.1 - 0.081 12.1 2.2 0.11 11.6 1.5 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein TcpE PF12648.2 EEQ34407.1 - 0.19 11.9 1.0 2.9 8.0 0.1 2.3 2 0 0 2 2 2 0 TcpE family CFEM PF05730.6 EEQ34409.1 - 3.2e-13 49.2 12.2 5.3e-13 48.5 8.5 1.4 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.11 EEQ34410.1 - 1.1e-34 119.7 26.9 1.1e-34 119.7 18.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ34410.1 - 1.8e-07 30.1 10.8 1.8e-07 30.1 7.5 3.0 2 2 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ34411.1 - 1.2e-12 47.2 40.9 1.2e-12 47.2 28.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEQ34411.1 - 1.6e-09 37.4 7.3 1.6e-09 37.4 5.1 3.0 2 2 2 4 4 4 1 Ion channel regulatory protein UNC-93 BcrAD_BadFG PF01869.15 EEQ34413.1 - 1.2e-07 31.2 0.0 4.9e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.1 EEQ34413.1 - 6.3e-06 25.9 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 SIS domain SIS PF01380.17 EEQ34413.1 - 0.00045 19.8 0.5 0.0016 18.0 0.0 2.0 2 0 0 2 2 2 1 SIS domain ADP_ribosyl_GH PF03747.9 EEQ34414.1 - 1.5e-41 143.0 0.3 5.5e-39 134.6 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylglycohydrolase Carb_anhydrase PF00194.16 EEQ34415.1 - 2e-18 66.3 2.3 5.1e-09 35.4 0.1 2.2 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase MIP-T3 PF10243.4 EEQ34417.1 - 1.1 7.6 33.9 1.6 7.0 23.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 EEQ34417.1 - 2.6 6.2 35.8 4.9 5.3 24.8 1.4 1 0 0 1 1 1 0 Transmembrane protein F-box-like PF12937.2 EEQ34418.1 - 0.063 13.0 0.2 0.2 11.4 0.2 1.9 1 0 0 1 1 1 0 F-box-like Peptidase_M14 PF00246.19 EEQ34418.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Zinc carboxypeptidase DUF1772 PF08592.6 EEQ34419.1 - 0.018 14.7 0.4 0.018 14.7 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Neurensin PF14927.1 EEQ34419.1 - 0.33 10.3 3.6 0.29 10.5 0.9 2.2 2 1 0 2 2 2 0 Neurensin Orbi_NS3 PF01616.11 EEQ34419.1 - 1.8 7.4 4.0 25 3.7 1.5 2.4 2 0 0 2 2 2 0 Orbivirus NS3 DnaJ PF00226.26 EEQ34420.1 - 1.4e-09 37.5 0.8 5.9e-09 35.5 0.5 2.1 1 1 0 1 1 1 1 DnaJ domain Acetyltransf_1 PF00583.19 EEQ34421.1 - 2.3e-08 33.9 0.0 4.7e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ34421.1 - 2.3e-08 34.0 0.0 4.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ34421.1 - 2.1e-07 30.8 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ34421.1 - 9e-05 22.1 0.0 0.00089 18.9 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ34421.1 - 0.00014 21.9 0.0 0.0036 17.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ34421.1 - 0.07 13.0 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ34421.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PRA1 PF03208.14 EEQ34422.1 - 1.3e-31 109.0 4.3 4.8e-31 107.1 3.1 1.7 2 0 0 2 2 2 1 PRA1 family protein Sarcoglycan_1 PF04790.8 EEQ34422.1 - 0.25 10.5 1.0 0.39 9.8 0.7 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein APH PF01636.18 EEQ34423.1 - 0.0002 21.1 0.0 0.00095 18.9 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Frag1 PF10277.4 EEQ34424.1 - 4.2e-31 108.1 11.3 4.8e-31 107.9 7.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Patched PF02460.13 EEQ34424.1 - 0.3 8.9 2.9 0.46 8.3 2.0 1.2 1 0 0 1 1 1 0 Patched family Arteri_Gl PF00951.13 EEQ34424.1 - 0.32 10.5 8.0 0.11 12.1 3.0 1.9 1 1 0 2 2 2 0 Arterivirus GL envelope glycoprotein MFS_Mycoplasma PF07672.8 EEQ34424.1 - 0.58 9.2 11.8 2.3 7.3 8.0 2.0 1 1 0 1 1 1 0 Mycoplasma MFS transporter DUF998 PF06197.8 EEQ34424.1 - 0.79 8.9 13.3 8 5.7 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Keratin_assoc PF09775.4 EEQ34424.1 - 2.1 7.9 11.4 2.6 7.5 5.9 2.1 1 1 1 2 2 2 0 Keratinocyte-associated protein 2 MFS_1 PF07690.11 EEQ34425.1 - 5.5e-41 140.4 28.1 8.8e-41 139.7 19.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ34425.1 - 2e-10 39.8 11.4 2e-10 39.8 7.9 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EEQ34425.1 - 0.00032 20.4 1.3 0.16 11.7 0.4 3.3 3 0 0 3 3 3 2 MFS_1 like family SNF2_N PF00176.18 EEQ34426.1 - 4.5e-54 183.2 2.1 5.3e-54 183.0 0.0 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 EEQ34426.1 - 2.1e-09 36.8 8.5 5.9e-09 35.4 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ34426.1 - 4.9e-08 32.6 10.0 1.1e-07 31.5 7.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ34426.1 - 1.3e-07 31.5 10.9 3.2e-07 30.2 7.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ34426.1 - 1.9e-07 30.6 7.5 1.9e-07 30.6 5.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ34426.1 - 4e-05 23.2 8.3 9.1e-05 22.1 5.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EEQ34426.1 - 5.6e-05 23.1 5.9 0.00015 21.7 4.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger Helicase_C PF00271.26 EEQ34426.1 - 0.00041 20.1 0.0 0.00098 18.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EEQ34426.1 - 0.00043 20.0 8.3 0.001 18.8 5.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ34426.1 - 0.003 17.2 5.4 0.016 14.9 3.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 EEQ34426.1 - 0.0064 16.2 0.5 0.015 15.0 0.4 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 EEQ34426.1 - 0.012 15.1 4.7 0.027 14.0 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EEQ34426.1 - 0.033 13.7 4.7 0.1 12.2 3.3 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ResIII PF04851.10 EEQ34426.1 - 0.037 13.8 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-UDP PF14569.1 EEQ34426.1 - 0.13 12.0 1.5 0.46 10.2 1.1 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger Mito_carr PF00153.22 EEQ34427.1 - 4.2e-67 221.9 0.1 1.4e-21 76.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 EEQ34427.1 - 0.0087 15.5 0.0 0.38 10.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) Ecm29 PF13001.2 EEQ34428.1 - 5.7e-152 506.7 0.9 7.1e-150 499.8 0.0 3.6 4 1 0 4 4 4 1 Proteasome stabiliser HEAT PF02985.17 EEQ34428.1 - 1.2e-07 31.1 0.0 21 5.5 0.0 9.6 12 0 0 12 12 12 1 HEAT repeat HEAT_EZ PF13513.1 EEQ34428.1 - 3.5e-06 27.3 8.3 0.62 10.6 0.0 7.5 8 0 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.1 EEQ34428.1 - 0.00047 20.3 16.3 0.46 10.7 0.9 7.5 8 2 2 10 10 10 3 HEAT repeats Vac14_Fab1_bd PF12755.2 EEQ34428.1 - 0.021 15.1 1.0 0.4 11.0 0.1 3.9 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region Fungal_trans_2 PF11951.3 EEQ34430.1 - 3.6e-18 65.3 0.4 2.1e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain FSIP1 PF15554.1 EEQ34430.1 - 0.16 10.7 1.1 0.26 10.0 0.8 1.3 1 0 0 1 1 1 0 FSIP1 family Peptidase_C13 PF01650.13 EEQ34431.1 - 0.068 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family Raptor_N PF14538.1 EEQ34431.1 - 0.091 12.5 0.4 0.34 10.7 0.3 1.9 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF3176 PF11374.3 EEQ34432.1 - 1.8e-37 127.5 1.0 3.8e-37 126.5 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Myb_DNA-bind_4 PF13837.1 EEQ34432.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain WW PF00397.21 EEQ34433.1 - 5.5e-09 35.7 0.6 1.4e-08 34.4 0.4 1.8 1 0 0 1 1 1 1 WW domain Lipase_3 PF01764.20 EEQ34434.1 - 4.6e-32 110.5 0.0 7.6e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Metallophos PF00149.23 EEQ34434.1 - 0.021 14.2 0.0 0.063 12.6 0.0 1.7 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Abhydrolase_5 PF12695.2 EEQ34434.1 - 0.036 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family GHMP_kinases_C PF08544.8 EEQ34434.1 - 0.037 14.2 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 GHMP kinases C terminal DUF2974 PF11187.3 EEQ34434.1 - 0.042 13.2 0.0 0.69 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF4006 PF13179.1 EEQ34434.1 - 0.051 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF1625 PF07787.7 EEQ34434.1 - 0.057 12.6 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Glyco_trans_1_4 PF13692.1 EEQ34434.1 - 0.096 12.8 0.0 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferases group 1 Esterase PF00756.15 EEQ34434.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 EEQ34434.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein WD40 PF00400.27 EEQ34435.1 - 6.1e-20 70.2 10.4 4.8e-06 26.2 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 EEQ34435.1 - 0.017 14.3 0.2 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity RRM_5 PF13893.1 EEQ34436.1 - 1.5e-09 37.5 0.1 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ34436.1 - 1.9e-07 30.5 0.0 4.8e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ34436.1 - 1.3e-05 25.0 0.0 3.2e-05 23.8 0.0 1.7 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Autophagy_act_C PF03987.10 EEQ34437.1 - 1.2e-09 38.1 0.4 7.7e-09 35.6 0.3 2.3 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Sulfatase PF00884.18 EEQ34438.1 - 3.4e-78 262.9 0.0 4.3e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EEQ34438.1 - 1e-05 24.1 0.0 2.7e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF229) MFS_1 PF07690.11 EEQ34440.1 - 4.5e-07 28.9 19.7 4.5e-07 28.9 13.6 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ34440.1 - 0.00066 18.3 16.4 0.00066 18.3 11.4 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter Bac_rhodopsin PF01036.13 EEQ34442.1 - 9.9e-25 87.1 13.3 1.2e-24 86.8 9.2 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HSP20 PF00011.16 EEQ34445.1 - 1.2e-19 70.0 0.2 3.1e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family FAA_hydrolase PF01557.13 EEQ34446.1 - 4.4e-61 206.0 0.0 5.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Proteasome PF00227.21 EEQ34447.1 - 8.1e-27 93.7 0.0 1e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 EEQ34448.1 - 6e-31 106.3 0.2 9.1e-31 105.7 0.2 1.3 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.21 EEQ34449.1 - 1.4e-31 109.2 0.1 3e-31 108.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit KH_1 PF00013.24 EEQ34450.1 - 0.00036 20.1 1.2 0.0007 19.1 0.8 1.5 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 EEQ34451.1 - 4.2e-197 655.5 2.9 5.3e-197 655.2 2.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins RhoGAP PF00620.22 EEQ34452.1 - 2.6e-40 137.5 0.0 5.6e-40 136.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EEQ34452.1 - 1e-11 44.9 2.5 1.6e-11 44.3 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EEQ34452.1 - 1.7e-07 31.5 0.0 5.5e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EEQ34452.1 - 0.022 14.7 0.0 0.072 13.1 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PRTP PF01366.13 EEQ34452.1 - 4.6 5.1 12.4 0.24 9.3 0.6 2.4 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Erv26 PF04148.8 EEQ34453.1 - 3.5e-63 212.7 0.4 7.2e-56 188.9 0.0 2.2 1 1 1 2 2 2 2 Transmembrane adaptor Erv26 WBS_methylT PF12589.3 EEQ34454.1 - 1.3e-17 63.9 3.4 2.3e-17 63.2 2.4 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EEQ34454.1 - 3.5e-10 40.2 0.0 5.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ34454.1 - 2.6e-07 30.9 0.0 6.6e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ34454.1 - 7.1e-06 25.6 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ34454.1 - 0.00014 22.4 0.0 0.0003 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ34454.1 - 0.00024 21.4 0.0 0.0006 20.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ34454.1 - 0.00054 19.5 0.0 0.00084 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EEQ34454.1 - 0.00055 19.6 0.0 0.00079 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ34454.1 - 0.0015 18.5 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ34454.1 - 0.0023 17.0 0.0 0.028 13.5 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ACT_7 PF13840.1 EEQ34454.1 - 0.17 11.4 0.1 0.34 10.4 0.1 1.4 1 0 0 1 1 1 0 ACT domain Iso_dh PF00180.15 EEQ34455.1 - 1.1e-83 281.0 0.0 1.4e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Proteasome PF00227.21 EEQ34459.1 - 6.6e-46 155.9 0.2 2.9e-32 111.5 0.0 2.9 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EEQ34459.1 - 9.1e-12 44.0 0.9 1.1e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DMRL_synthase PF00885.14 EEQ34460.1 - 1e-45 154.9 0.3 3.9e-25 88.2 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase SIS PF01380.17 EEQ34461.1 - 2.1e-53 179.3 0.0 6.7e-30 103.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EEQ34461.1 - 4.5e-24 84.8 0.0 9.5e-20 70.6 0.0 2.7 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEQ34461.1 - 1.1e-19 70.7 0.0 2.3e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EEQ34461.1 - 1.1e-12 47.8 0.0 2.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EEQ34461.1 - 1.1e-07 30.7 0.0 2.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EEQ34461.1 - 0.0022 17.6 0.0 0.39 10.4 0.0 2.6 2 0 0 2 2 2 1 SIS domain N-SET PF11764.3 EEQ34462.1 - 2.8e-49 167.2 0.7 2.8e-49 167.2 0.5 2.6 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EEQ34462.1 - 1.3e-25 88.4 0.3 2.5e-25 87.5 0.2 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EEQ34462.1 - 1.5e-24 87.0 0.6 1.5e-23 83.8 0.2 3.0 2 1 0 2 2 2 1 SET domain RRM_1 PF00076.17 EEQ34462.1 - 3.2e-06 26.6 0.0 7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ34462.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Trm112p PF03966.11 EEQ34463.1 - 8.4e-15 54.8 0.1 1.1e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Rad60-SLD PF11976.3 EEQ34464.1 - 1.7e-21 75.6 0.2 3.3e-20 71.5 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YL1 PF05764.8 EEQ34464.1 - 0.034 13.7 17.2 0.067 12.7 1.7 2.4 2 0 0 2 2 2 0 YL1 nuclear protein PBP1_TM PF14812.1 EEQ34464.1 - 4.4 7.6 12.5 1.4 9.2 0.3 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LSM PF01423.17 EEQ34465.1 - 1.9e-18 65.7 0.0 2.2e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEQ34465.1 - 0.005 16.7 0.1 0.0058 16.5 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1106 PF06523.6 EEQ34465.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) IF-2B PF01008.12 EEQ34466.1 - 2.1e-70 236.9 1.0 2.5e-70 236.6 0.7 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF892 PF05974.7 EEQ34467.1 - 0.025 14.4 0.8 0.026 14.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Exonuc_VII_S PF02609.11 EEQ34467.1 - 0.075 12.8 2.0 0.31 10.8 0.1 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit Macoilin PF09726.4 EEQ34467.1 - 0.39 8.9 4.0 0.41 8.8 2.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Ax_dynein_light PF10211.4 EEQ34467.1 - 0.87 9.4 4.2 0.91 9.3 2.9 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4407 PF14362.1 EEQ34467.1 - 1.7 7.5 5.4 1.8 7.4 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GST_C PF00043.20 EEQ34469.1 - 1.6e-13 50.4 0.1 2.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ34469.1 - 1.4e-11 44.4 0.0 2.3e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEQ34469.1 - 1.9e-09 37.5 0.0 3.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ34469.1 - 2.5e-08 33.7 0.2 4.4e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEQ34469.1 - 6e-08 32.5 0.0 1.7e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEQ34469.1 - 1.2e-05 25.7 0.6 1.7e-05 25.1 0.4 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EEQ34469.1 - 0.016 15.6 0.0 0.038 14.3 0.0 1.7 1 1 0 1 1 1 0 MetRS-N binding domain Adaptin_N PF01602.15 EEQ34472.1 - 1.2e-57 195.4 0.0 4.1e-57 193.7 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EEQ34472.1 - 0.052 13.6 0.2 22 5.4 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Cnd1 PF12717.2 EEQ34472.1 - 0.15 11.9 2.0 0.61 9.9 0.2 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF4604 PF15377.1 EEQ34472.1 - 1.1 9.4 27.5 2.9 8.0 13.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) TFIIF_alpha PF05793.7 EEQ34472.1 - 1.9 6.7 19.4 0.032 12.6 8.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPR_14 PF13428.1 EEQ34473.1 - 1.9e-07 31.1 2.6 0.081 13.5 0.0 4.7 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ34473.1 - 2.2e-07 30.4 0.5 0.00042 19.9 0.2 4.2 3 1 1 4 4 4 2 TPR repeat TPR_19 PF14559.1 EEQ34473.1 - 2e-05 24.8 1.5 0.51 10.7 0.0 3.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ34473.1 - 0.00019 21.3 0.1 0.095 12.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ34473.1 - 0.00021 20.9 0.4 0.029 14.2 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ34473.1 - 0.00036 21.1 4.5 0.19 12.4 0.0 4.8 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ34473.1 - 0.0024 17.5 0.5 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ34473.1 - 0.0032 17.3 2.8 1.4 8.9 0.0 3.5 2 1 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 EEQ34473.1 - 0.024 14.9 0.4 7.8 6.7 0.0 2.7 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_1 PF00515.23 EEQ34473.1 - 0.076 12.6 0.0 1.7 8.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 EEQ34473.1 - 0.081 13.2 0.1 0.32 11.3 0.0 2.1 2 0 0 2 2 1 0 Pentatricopeptide repeat domain Radial_spoke PF04712.7 EEQ34474.1 - 0.034 12.9 1.7 0.039 12.7 1.2 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein Nucleoplasmin PF03066.10 EEQ34475.1 - 0.45 10.0 11.1 1.3 8.5 7.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin DUF940 PF06082.6 EEQ34475.1 - 9.7 4.6 6.4 16 3.9 4.4 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) bZIP_2 PF07716.10 EEQ34476.1 - 0.37 10.6 2.6 0.55 10.1 1.8 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Kinesin PF00225.18 EEQ34477.1 - 9.5e-98 326.9 0.1 2e-97 325.8 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain CENP-Q PF13094.1 EEQ34477.1 - 0.038 14.0 13.1 0.62 10.0 2.1 3.0 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Ank_2 PF12796.2 EEQ34478.1 - 3.6e-105 344.5 6.8 5.9e-21 74.6 0.1 5.9 2 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ34478.1 - 1.7e-83 270.4 0.3 5.3e-07 29.1 0.1 12.2 12 0 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.1 EEQ34478.1 - 1.7e-62 201.1 0.3 7.3e-05 22.6 0.0 12.3 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 EEQ34478.1 - 1.3e-61 203.9 8.0 2.3e-11 43.8 0.0 9.2 3 3 7 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ34478.1 - 5.3e-53 175.8 9.5 3.5e-10 39.7 0.0 8.5 2 1 7 10 10 10 9 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 EEQ34478.1 - 0.068 12.6 0.6 59 3.0 0.0 4.7 4 2 3 7 7 7 0 Shigella flexneri OspC protein NOGCT PF08155.6 EEQ34480.1 - 0.015 14.9 0.2 0.036 13.7 0.1 1.6 1 0 0 1 1 1 0 NOGCT (NUC087) domain DAGAT PF03982.8 EEQ34481.1 - 1.6e-90 302.7 0.0 2e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EEQ34481.1 - 0.035 13.6 3.8 0.069 12.7 2.6 1.4 1 0 0 1 1 1 0 Rer1 family G-patch PF01585.18 EEQ34483.1 - 0.0012 18.6 0.0 0.027 14.2 0.0 2.7 2 0 0 2 2 2 1 G-patch domain BLVR PF06375.6 EEQ34483.1 - 0.31 10.8 37.7 0.93 9.3 11.0 2.5 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) MIP-T3 PF10243.4 EEQ34483.1 - 0.7 8.2 40.6 0.96 7.8 28.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Baculo_PP31 PF05311.6 EEQ34483.1 - 0.82 8.8 19.2 0.029 13.6 2.5 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) U1snRNP70_N PF12220.3 EEQ34483.1 - 1.1 9.5 18.0 7.7 6.9 0.5 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF966 PF06136.8 EEQ34483.1 - 1.8 7.8 20.1 2.5 7.4 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.2 EEQ34483.1 - 2.8 5.5 13.6 3.4 5.2 9.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.1 EEQ34483.1 - 6.5 5.6 10.3 10 4.9 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2852 PF11014.3 EEQ34484.1 - 0.07 13.0 0.7 0.097 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) RapA_C PF12137.3 EEQ34484.1 - 0.076 11.8 6.7 0.089 11.6 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal YaeQ PF07152.7 EEQ34484.1 - 0.077 12.3 1.1 0.1 11.9 0.8 1.2 1 0 0 1 1 1 0 YaeQ protein DGCR6 PF07324.6 EEQ34484.1 - 0.14 11.6 6.1 0.19 11.1 4.2 1.3 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein DUF4473 PF14747.1 EEQ34484.1 - 0.17 12.0 4.1 0.1 12.8 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4473) ISG65-75 PF11727.3 EEQ34484.1 - 0.42 9.6 9.2 0.58 9.1 6.3 1.3 1 1 0 1 1 1 0 Invariant surface glycoprotein Syja_N PF02383.13 EEQ34485.1 - 3.7e-82 275.6 0.0 5.4e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EEQ34485.1 - 1.4e-26 93.9 0.2 5.3e-26 92.0 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF3275 PF11679.3 EEQ34485.1 - 0.15 11.7 1.1 0.28 10.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Pkinase PF00069.20 EEQ34486.1 - 2.7e-57 193.9 0.0 3.4e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34486.1 - 3.9e-30 104.7 0.0 6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ34486.1 - 0.12 12.0 0.1 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family IGR PF09597.5 EEQ34487.1 - 4.6e-18 64.8 0.8 7.6e-18 64.1 0.6 1.3 1 0 0 1 1 1 1 IGR protein motif p450 PF00067.17 EEQ34488.1 - 2.9e-70 237.0 0.0 3.7e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EEQ34489.1 - 9.9e-67 224.8 0.0 1.5e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34489.1 - 1.4e-34 119.3 0.0 2e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EEQ34489.1 - 3.4e-16 59.1 0.5 6.5e-16 58.2 0.3 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EEQ34489.1 - 9.2e-07 28.1 0.0 3.6e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EEQ34489.1 - 0.0089 14.8 0.1 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EEQ34489.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.22 EEQ34490.1 - 1.4e-35 122.8 0.0 1.3e-34 119.6 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EEQ34490.1 - 2.1e-24 85.7 0.2 4.8e-24 84.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CorA PF01544.13 EEQ34492.1 - 0.024 13.6 3.1 0.048 12.6 2.1 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein WBP-1 PF11669.3 EEQ34492.1 - 0.045 13.8 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF4401 PF14351.1 EEQ34492.1 - 0.082 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) PepSY_TM_2 PF13703.1 EEQ34492.1 - 0.14 12.3 1.6 0.32 11.1 0.4 2.1 2 0 0 2 2 2 0 PepSY-associated TM helix ArfGap PF01412.13 EEQ34494.1 - 4e-33 113.6 1.6 1.6e-32 111.7 0.0 2.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EEQ34494.1 - 1.6e-13 50.7 0.1 6.5e-13 48.7 0.1 2.1 2 0 0 2 2 2 1 PH domain LSM PF01423.17 EEQ34495.1 - 1.2e-19 69.5 0.1 1.4e-19 69.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain Ank_2 PF12796.2 EEQ34496.1 - 1e-81 269.3 8.9 1.3e-15 57.5 0.0 6.8 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ34496.1 - 2.8e-47 158.2 11.0 4e-08 33.5 0.8 11.0 4 2 6 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.25 EEQ34496.1 - 3.9e-47 155.7 14.9 3.2e-08 32.9 0.1 12.2 11 2 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 EEQ34496.1 - 3.4e-36 122.4 12.5 1.8e-07 31.1 0.2 8.3 6 2 4 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ34496.1 - 1.2e-35 117.9 7.3 0.00025 20.9 0.1 12.7 12 1 0 12 12 12 7 Ankyrin repeat gag-asp_proteas PF13975.1 EEQ34496.1 - 0.044 13.5 0.1 3.7 7.4 0.0 3.2 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EEQ34496.1 - 0.084 13.3 0.2 11 6.6 0.0 3.7 3 1 1 4 4 4 0 Aspartyl protease ChlamPMP_M PF07548.6 EEQ34496.1 - 0.091 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain RVP PF00077.15 EEQ34496.1 - 0.097 12.5 0.1 13 5.7 0.0 3.6 3 0 0 3 3 3 0 Retroviral aspartyl protease AA_permease PF00324.16 EEQ34497.1 - 8.8e-129 429.9 36.2 1.1e-128 429.6 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ34497.1 - 2.6e-32 111.9 36.7 3.3e-32 111.5 25.4 1.1 1 0 0 1 1 1 1 Amino acid permease APH PF01636.18 EEQ34498.1 - 0.00055 19.7 0.0 0.0052 16.5 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family FCH PF00611.18 EEQ34499.1 - 1.6e-15 57.0 0.6 8.7e-15 54.6 0.0 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EEQ34499.1 - 5.3e-13 48.8 0.0 5.3e-13 48.8 0.0 2.5 3 0 0 3 3 3 1 RhoGAP domain DEP PF00610.16 EEQ34499.1 - 1.3e-09 37.6 0.0 2.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RTA1 PF04479.8 EEQ34500.1 - 6.8e-16 58.4 0.4 9.4e-16 57.9 0.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Asp-Al_Ex PF06826.7 EEQ34500.1 - 0.0067 15.9 0.8 0.013 15.0 0.5 1.4 1 0 0 1 1 1 1 Predicted Permease Membrane Region AAA PF00004.24 EEQ34501.1 - 1e-14 54.8 0.0 2.6e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ34501.1 - 1.5e-14 54.2 0.0 3.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ34501.1 - 1.7e-14 54.2 0.3 1.1e-12 48.3 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.6 EEQ34501.1 - 2.2e-06 27.3 0.0 5.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal TIP49 PF06068.8 EEQ34501.1 - 6.7e-06 25.0 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EEQ34501.1 - 0.002 18.9 0.0 0.0045 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EEQ34501.1 - 0.0026 17.4 0.0 0.0071 16.0 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 EEQ34501.1 - 0.0027 16.7 0.0 0.0046 15.9 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.1 EEQ34501.1 - 0.0031 17.2 0.0 0.0093 15.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EEQ34501.1 - 0.0045 15.9 0.0 0.0086 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.9 EEQ34501.1 - 0.0076 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PIF1 PF05970.9 EEQ34501.1 - 0.0091 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_14 PF13173.1 EEQ34501.1 - 0.0096 15.8 0.0 0.028 14.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EEQ34501.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EEQ34501.1 - 0.013 14.4 0.0 0.037 12.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EEQ34501.1 - 0.03 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EEQ34501.1 - 0.041 13.5 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 1 0 NTPase AAA_28 PF13521.1 EEQ34501.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EEQ34501.1 - 0.069 12.1 0.0 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus RNA12 PF10443.4 EEQ34501.1 - 0.069 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein Rad17 PF03215.10 EEQ34501.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 EEQ34501.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 EEQ34501.1 - 0.17 10.6 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein UBA_4 PF14555.1 EEQ34502.1 - 6.6e-14 51.1 0.0 1.4e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EEQ34502.1 - 3.2e-13 49.5 0.0 7.7e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EEQ34502.1 - 3.7e-07 30.1 0.0 9.5e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.20 EEQ34504.1 - 2.8e-69 233.1 0.0 4.1e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34504.1 - 1.3e-49 168.6 0.0 2e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ34504.1 - 0.00063 18.7 0.0 0.023 13.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Fungal_trans PF04082.13 EEQ34505.1 - 2.2e-21 75.9 0.3 3.7e-21 75.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ34505.1 - 0.19 11.6 2.8 0.35 10.8 1.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 EEQ34506.1 - 1.3e-21 76.6 0.0 2.2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EEQ34506.1 - 5.9e-10 39.5 0.0 1.1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EEQ34506.1 - 9.1e-09 35.3 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short PF00106.20 EEQ34507.1 - 1.5e-22 80.2 0.4 5.4e-22 78.4 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ34507.1 - 1.9e-21 76.9 0.0 2.2e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ34507.1 - 5.9e-07 29.3 0.0 1.3e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF3431 PF11913.3 EEQ34508.1 - 5.9e-85 284.2 0.2 9.3e-85 283.6 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) APH PF01636.18 EEQ34510.1 - 1.3e-10 41.4 0.0 2.2e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ34510.1 - 0.00074 19.1 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EEQ34510.1 - 0.0014 17.7 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase PAAR_motif PF05488.8 EEQ34510.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 PAAR motif Amidohydro_2 PF04909.9 EEQ34511.1 - 2e-15 57.0 0.0 3.8e-15 56.1 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase ADH_N PF08240.7 EEQ34512.1 - 7.8e-26 89.9 0.5 1.5e-25 89.1 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ34512.1 - 1.5e-22 79.5 0.2 2.1e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SWIM PF04434.12 EEQ34513.1 - 3.3e-06 26.4 0.1 6.3e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger DHC_N1 PF08385.7 EEQ34513.1 - 0.19 10.0 0.0 0.39 9.0 0.0 1.4 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 Anophelin PF10731.4 EEQ34513.1 - 3.2 7.9 5.8 7.6 6.7 4.0 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito TPR_11 PF13414.1 EEQ34515.1 - 4.6e-07 29.3 0.5 1.2e-06 28.0 0.3 1.7 1 0 0 1 1 1 1 TPR repeat SET PF00856.23 EEQ34515.1 - 3e-06 27.6 2.3 0.00035 20.9 0.1 3.3 3 0 0 3 3 3 1 SET domain TPR_16 PF13432.1 EEQ34515.1 - 0.0035 17.9 0.1 0.011 16.3 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ34515.1 - 0.043 13.4 0.1 0.65 9.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Allexi_40kDa PF05549.6 EEQ34516.1 - 0.00023 20.5 0.1 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 1 Allexivirus 40kDa protein Ribosomal_60s PF00428.14 EEQ34516.1 - 0.78 10.1 0.0 0.78 10.1 0.0 3.7 4 0 0 4 4 4 0 60s Acidic ribosomal protein zf-H2C2_2 PF13465.1 EEQ34517.1 - 1.8e-12 46.9 15.7 6e-06 26.2 1.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ34517.1 - 2.6e-09 36.8 23.1 0.014 15.6 4.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ34517.1 - 3.9e-06 26.7 21.9 0.0098 16.1 4.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ34517.1 - 0.0064 16.6 10.1 0.61 10.2 2.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EEQ34517.1 - 0.053 13.6 6.3 0.11 12.6 4.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EEQ34517.1 - 0.47 10.4 13.9 0.42 10.5 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CHCC PF10276.4 EEQ34517.1 - 0.96 9.3 4.9 7.4 6.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.2 EEQ34517.1 - 1.1 9.1 5.0 9.6 6.1 3.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_2 PF12756.2 EEQ34517.1 - 1.6 8.8 10.1 1.3 9.1 0.6 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 EEQ34517.1 - 2.1 8.3 7.9 10 6.1 2.4 3.3 1 1 1 2 2 2 0 Zinc ribbon domain GAGA PF09237.6 EEQ34517.1 - 9.5 5.8 13.0 3.2 7.4 1.1 3.2 2 1 1 3 3 3 0 GAGA factor DUF3074 PF11274.3 EEQ34518.1 - 2.8e-16 59.6 0.1 2.9e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) Stk19 PF10494.4 EEQ34519.1 - 9.1e-71 238.1 0.0 1.1e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.16 EEQ34520.1 - 1.2e-104 350.4 1.9 1.1e-64 218.6 0.0 2.3 1 1 1 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEQ34520.1 - 1.3e-36 125.6 0.0 1.7e-35 122.0 0.0 2.3 1 1 0 1 1 1 1 Trehalose-phosphatase HNF-1B_C PF04812.8 EEQ34522.1 - 0.02 14.1 0.2 0.022 14.0 0.2 1.0 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus DUF4232 PF14016.1 EEQ34522.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) 4HBT_3 PF13622.1 EEQ34523.1 - 1.9e-57 194.9 0.1 2.2e-57 194.7 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EEQ34524.1 - 2.8e-07 30.5 0.0 4.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Plasmodium_Vir PF05795.6 EEQ34525.1 - 0.04 13.1 0.8 0.043 13.0 0.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Herpes_capsid PF06112.6 EEQ34525.1 - 2.6 8.0 9.7 3.9 7.4 6.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CAF-1_p150 PF11600.3 EEQ34525.1 - 7.8 5.8 6.0 11 5.2 4.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 EEQ34525.1 - 8.7 4.3 6.1 10 4.0 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PCI PF01399.22 EEQ34526.1 - 2.3e-10 40.6 0.0 5.5e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain Ribosomal_S14 PF00253.16 EEQ34527.1 - 3.2e-17 61.6 3.8 3.8e-17 61.4 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 EEQ34527.1 - 0.55 10.3 3.4 16 5.6 0.1 2.2 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase ADK PF00406.17 EEQ34528.1 - 8.4e-40 136.0 0.0 1.3e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EEQ34528.1 - 1.3e-08 35.1 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ34528.1 - 7.7e-08 33.1 0.0 1.2e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ34528.1 - 2.7e-05 24.0 0.0 0.00022 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EEQ34528.1 - 0.0041 16.5 0.0 0.089 12.1 0.0 2.1 1 1 0 1 1 1 1 Thymidylate kinase MFS_1 PF07690.11 EEQ34529.1 - 1.1e-26 93.4 34.8 1.1e-26 93.4 24.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Glt_symporter PF03616.9 EEQ34529.1 - 0.2 10.1 9.1 0.043 12.3 0.9 2.3 2 0 0 2 2 2 0 Sodium/glutamate symporter Acyl_transf_3 PF01757.17 EEQ34529.1 - 3.2 6.5 33.1 0.56 8.9 8.0 2.4 2 1 0 2 2 2 0 Acyltransferase family Cnd2 PF05786.9 EEQ34531.1 - 3.3e-239 796.1 1.3 4e-239 795.9 0.9 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 EEQ34532.1 - 3e-46 156.4 36.6 6e-25 87.4 8.2 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein EF-hand_4 PF12763.2 EEQ34533.1 - 7.8e-25 86.6 0.0 1.2e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EEQ34533.1 - 5.1e-10 38.6 0.2 1.5e-09 37.1 0.1 1.9 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.6 EEQ34533.1 - 3.7e-07 30.1 56.1 5.8e-05 23.0 13.4 7.4 4 2 2 6 6 6 4 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 EEQ34533.1 - 0.00011 21.2 0.0 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EEQ34533.1 - 0.00014 21.9 0.0 0.013 15.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EEQ34533.1 - 0.0013 18.3 0.0 0.24 11.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ34533.1 - 0.087 12.7 0.0 12 6.0 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain RNA_pol_L_2 PF13656.1 EEQ34534.1 - 1.4e-23 82.1 0.0 2.2e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEQ34534.1 - 1.1e-12 46.8 0.0 1.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PG_binding_3 PF09374.5 EEQ34535.1 - 0.057 13.4 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain NMO PF03060.10 EEQ34536.1 - 4.3e-36 124.7 6.6 6.3e-35 120.8 4.6 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EEQ34536.1 - 3.1e-07 29.5 5.1 5.2e-07 28.8 3.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EEQ34536.1 - 9.6e-06 24.7 0.0 0.0057 15.5 1.1 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EEQ34536.1 - 0.0003 19.8 0.8 0.00043 19.3 0.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DUF3537 PF12056.3 EEQ34537.1 - 0.69 8.5 2.7 1.1 7.9 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) PBP1_TM PF14812.1 EEQ34538.1 - 0.074 13.3 8.1 0.11 12.8 5.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_29 PF00777.13 EEQ34538.1 - 0.11 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) DUF4611 PF15387.1 EEQ34538.1 - 0.28 11.3 3.6 0.44 10.7 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 EEQ34538.1 - 1.2 8.9 4.9 1.6 8.4 3.4 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Mur_ligase_M PF08245.7 EEQ34539.1 - 1.3e-05 25.3 0.0 3e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain LRR_8 PF13855.1 EEQ34540.1 - 0.00066 19.3 9.3 0.012 15.3 1.1 4.3 3 2 0 3 3 3 1 Leucine rich repeat Bcl-2_BAD PF10514.4 EEQ34540.1 - 0.022 14.7 3.0 0.043 13.7 2.1 1.4 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD LRR_2 PF07723.8 EEQ34540.1 - 0.1 13.1 0.8 4.8 7.8 0.1 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.2 EEQ34540.1 - 0.52 9.9 12.3 3.3 7.4 0.4 5.2 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEQ34540.1 - 1.1 9.5 11.7 25 5.4 0.0 6.2 8 1 0 8 8 8 0 Leucine Rich Repeat Paramyxo_ncap PF00973.14 EEQ34540.1 - 2.5 6.6 10.7 3.5 6.2 7.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LRR_6 PF13516.1 EEQ34540.1 - 7.1 7.0 11.8 29 5.1 0.0 5.7 8 0 0 8 8 8 0 Leucine Rich repeat DUF3752 PF12572.3 EEQ34540.1 - 7.8 6.6 19.8 0.23 11.5 9.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) SNF2_N PF00176.18 EEQ34541.1 - 6.1e-57 192.6 0.0 1.1e-56 191.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ34541.1 - 4.7e-12 45.6 0.0 1.1e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ34541.1 - 8.9e-09 35.4 0.0 2.8e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EEQ34541.1 - 7.9e-05 22.2 11.3 7.9e-05 22.2 7.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ34541.1 - 0.00038 20.2 11.6 0.00038 20.2 8.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ34541.1 - 0.0008 19.3 11.4 0.0008 19.3 7.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 EEQ34541.1 - 0.0014 17.5 0.0 0.0043 15.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.24 EEQ34541.1 - 0.0021 17.5 0.0 0.0054 16.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Zn_Tnp_IS91 PF14319.1 EEQ34541.1 - 0.0045 16.4 14.6 0.24 10.9 2.0 2.5 2 0 0 2 2 2 2 Transposase zinc-binding domain zf-RING_UBOX PF13445.1 EEQ34541.1 - 0.2 11.3 6.8 0.13 11.9 3.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger C2 PF00168.25 EEQ34542.1 - 7.6e-10 38.4 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Zip PF02535.17 EEQ34542.1 - 0.027 13.4 1.1 0.044 12.7 0.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Pex2_Pex12 PF04757.9 EEQ34543.1 - 1.7e-42 145.4 3.6 2.3e-42 145.0 2.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EEQ34543.1 - 3.2e-11 42.8 9.3 5.1e-11 42.2 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ34543.1 - 8.4e-11 41.3 7.1 1.3e-10 40.7 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ34543.1 - 2.7e-10 40.0 9.0 4.3e-10 39.4 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ34543.1 - 1.4e-09 37.4 5.3 2e-09 36.9 3.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ34543.1 - 3.4e-08 33.0 6.4 5.3e-08 32.4 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEQ34543.1 - 3.6e-06 26.5 1.9 4.8e-06 26.1 0.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEQ34543.1 - 4.4e-06 26.4 9.0 7.4e-06 25.7 6.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EEQ34543.1 - 3.2e-05 23.9 7.4 7.3e-05 22.7 5.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EEQ34543.1 - 0.00082 19.1 2.8 0.0015 18.2 2.0 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EEQ34543.1 - 0.0071 16.1 3.1 0.012 15.3 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EEQ34543.1 - 0.013 15.0 4.8 0.024 14.1 3.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EEQ34543.1 - 0.14 11.7 8.3 0.27 10.8 5.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EEQ34543.1 - 1.3 8.9 7.1 3.5 7.5 4.9 1.8 1 1 0 1 1 1 0 IBR domain EXS PF03124.9 EEQ34544.1 - 2.3e-93 312.9 4.3 2.6e-93 312.8 3.0 1.0 1 0 0 1 1 1 1 EXS family DUF3431 PF11913.3 EEQ34545.1 - 1.1e-86 289.9 0.4 1.4e-86 289.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3328 PF11807.3 EEQ34546.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) ATP-synt_S1 PF05827.7 EEQ34547.1 - 2.9e-36 125.2 2.5 1.3e-21 77.1 0.7 2.4 1 1 1 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.4 EEQ34548.1 - 1.4e-17 64.0 8.8 3.3e-13 49.8 0.3 3.9 2 2 2 4 4 4 2 Nucleolar protein 12 (25kDa) TATR PF03430.8 EEQ34548.1 - 3 6.3 9.2 3.4 6.1 6.3 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Tropomyosin_1 PF12718.2 EEQ34549.1 - 4.1e-47 159.6 36.1 5.2e-47 159.2 25.0 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EEQ34549.1 - 1.1e-11 44.3 36.5 1.5e-06 27.4 10.7 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.4 EEQ34549.1 - 0.00021 21.3 11.9 0.00021 21.3 8.2 2.9 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.4 EEQ34549.1 - 0.00081 19.2 35.0 0.0016 18.2 4.2 3.2 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EEQ34549.1 - 0.0022 17.2 31.8 0.026 13.7 17.3 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 EEQ34549.1 - 0.0045 16.7 8.1 0.0045 16.7 5.6 2.1 1 1 1 2 2 2 1 Laminin Domain II Spc7 PF08317.6 EEQ34549.1 - 0.0055 15.4 28.7 0.25 9.9 9.0 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein IncA PF04156.9 EEQ34549.1 - 0.027 14.0 34.0 2.7 7.5 23.6 2.2 1 1 0 1 1 1 0 IncA protein MS_channel PF00924.13 EEQ34549.1 - 0.034 13.4 3.3 0.041 13.1 2.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Sugarporin_N PF11471.3 EEQ34549.1 - 0.036 13.7 4.1 0.036 13.7 2.9 3.9 3 2 1 4 4 3 0 Maltoporin periplasmic N-terminal extension TMP_2 PF06791.8 EEQ34549.1 - 0.046 13.3 4.5 0.045 13.3 2.6 1.4 1 1 0 1 1 1 0 Prophage tail length tape measure protein Meckelin PF09773.4 EEQ34549.1 - 0.047 11.4 0.7 0.049 11.3 0.5 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Mod_r PF07200.8 EEQ34549.1 - 0.067 13.1 28.3 0.32 10.9 13.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein AAA_13 PF13166.1 EEQ34549.1 - 0.067 11.6 25.3 0.12 10.7 17.5 1.5 1 1 0 1 1 1 0 AAA domain ERM PF00769.14 EEQ34549.1 - 0.07 12.6 37.6 0.049 13.1 11.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family SlyX PF04102.7 EEQ34549.1 - 0.071 13.4 25.7 0.2 12.0 6.1 3.2 1 1 3 4 4 4 0 SlyX ADIP PF11559.3 EEQ34549.1 - 0.09 12.6 33.7 1.1 9.1 7.6 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF869 PF05911.6 EEQ34549.1 - 0.091 10.9 26.4 0.68 8.0 8.8 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) TMF_DNA_bd PF12329.3 EEQ34549.1 - 0.11 12.3 36.9 0.043 13.6 9.6 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EEQ34549.1 - 0.11 12.3 30.8 2 8.2 6.1 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 EEQ34549.1 - 0.12 12.1 36.9 0.76 9.5 6.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 EEQ34549.1 - 0.13 12.2 34.9 0.91 9.4 10.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.4 EEQ34549.1 - 0.18 11.9 21.4 1.6 8.9 5.1 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EEQ34549.1 - 0.18 10.9 4.5 1.5 7.9 0.2 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 EEQ34549.1 - 0.2 11.0 30.0 1.4 8.3 8.6 2.0 1 1 1 2 2 2 0 Intermediate filament protein Atg14 PF10186.4 EEQ34549.1 - 0.21 10.5 30.7 0.071 12.0 14.7 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 EEQ34549.1 - 0.27 11.2 26.1 0.9 9.5 0.7 4.0 1 1 3 4 4 4 0 bZIP transcription factor DUF1465 PF07323.7 EEQ34549.1 - 0.27 10.7 18.6 0.061 12.8 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) DUF1664 PF07889.7 EEQ34549.1 - 0.31 10.8 15.7 0.27 11.0 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MAD PF05557.8 EEQ34549.1 - 0.44 8.5 27.9 0.85 7.6 18.8 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein Toprim_C_rpt PF13368.1 EEQ34549.1 - 0.51 10.8 7.2 1.3 9.5 1.3 2.5 2 1 0 2 2 2 0 Topoisomerase C-terminal repeat Fib_alpha PF08702.5 EEQ34549.1 - 0.62 10.1 19.6 5.5 7.1 8.1 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 EEQ34549.1 - 0.63 7.3 28.8 0.92 6.7 20.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PilJ PF13675.1 EEQ34549.1 - 0.64 10.3 15.2 1.2 9.4 4.3 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term APG6 PF04111.7 EEQ34549.1 - 0.68 8.9 35.2 0.94 8.4 12.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 EzrA PF06160.7 EEQ34549.1 - 0.69 8.0 24.7 0.32 9.1 5.1 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF3287 PF11690.3 EEQ34549.1 - 0.77 9.8 8.0 1.3 9.1 3.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) Striatin PF08232.7 EEQ34549.1 - 0.8 10.0 29.6 0.5 10.6 13.1 2.3 1 1 0 2 2 2 0 Striatin family BRCA-2_OB3 PF09104.5 EEQ34549.1 - 0.88 9.3 7.5 9.2 6.0 0.1 3.3 1 1 3 4 4 4 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 PLAC9 PF15205.1 EEQ34549.1 - 0.88 9.8 3.2 2.1 8.6 0.3 2.8 1 1 2 3 3 2 0 Placenta-specific protein 9 FlaC_arch PF05377.6 EEQ34549.1 - 1.2 9.0 19.0 2 8.3 2.9 4.1 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) IFT46_B_C PF12317.3 EEQ34549.1 - 1.6 8.0 8.3 0.67 9.2 3.7 1.6 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF2458 PF10454.4 EEQ34549.1 - 1.8 8.4 23.4 0.28 11.0 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) FUSC PF04632.7 EEQ34549.1 - 2.3 6.5 9.1 2.4 6.4 6.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Laminin_I PF06008.9 EEQ34549.1 - 2.4 7.4 29.9 0.28 10.4 8.1 3.0 1 1 2 3 3 3 0 Laminin Domain I DUF2228 PF10228.4 EEQ34549.1 - 2.4 7.6 9.5 0.46 9.9 3.6 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) Myb_DNA-bind_4 PF13837.1 EEQ34549.1 - 2.6 8.2 11.0 4 7.6 2.6 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DUF972 PF06156.8 EEQ34549.1 - 2.8 8.3 26.6 6.8 7.0 9.1 2.9 1 1 1 2 2 1 0 Protein of unknown function (DUF972) Cep57_MT_bd PF06657.8 EEQ34549.1 - 2.8 7.9 20.7 0.1 12.5 2.6 3.7 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Phage_GP20 PF06810.6 EEQ34549.1 - 3.2 7.1 27.8 2.6 7.4 9.6 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Vps5 PF09325.5 EEQ34549.1 - 4 6.6 25.1 0.56 9.4 7.0 2.7 1 1 2 3 3 3 0 Vps5 C terminal like DUF724 PF05266.9 EEQ34549.1 - 5.6 6.5 29.3 1.1 8.9 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4201 PF13870.1 EEQ34549.1 - 6 6.2 28.5 12 5.3 19.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DivIC PF04977.10 EEQ34549.1 - 9 5.8 33.8 0.9 9.0 1.0 4.4 1 1 2 4 4 4 0 Septum formation initiator DUF342 PF03961.8 EEQ34549.1 - 9.1 4.5 27.2 0.76 8.1 8.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Corona_nucleoca PF00937.13 EEQ34550.1 - 0.0026 16.7 13.6 0.0044 16.0 9.4 1.5 1 1 0 1 1 1 1 Coronavirus nucleocapsid protein CMAS PF02353.15 EEQ34551.1 - 1.9e-60 204.2 0.0 2.4e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EEQ34551.1 - 1.3e-12 47.7 0.0 3.8e-12 46.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ34551.1 - 2.4e-07 31.1 0.0 4.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ34551.1 - 0.00039 20.9 0.0 0.00082 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ34551.1 - 0.001 19.4 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ34551.1 - 0.0016 18.4 0.0 0.0057 16.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ34551.1 - 0.0037 16.8 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ34551.1 - 0.0067 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEQ34551.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EEQ34551.1 - 0.015 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 N6_N4_Mtase PF01555.13 EEQ34551.1 - 0.029 13.8 0.0 5.4 6.4 0.0 2.4 2 0 0 2 2 2 0 DNA methylase PCMT PF01135.14 EEQ34551.1 - 0.045 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EEQ34551.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase AMP-binding PF00501.23 EEQ34552.1 - 2.2e-69 233.8 0.1 2.8e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ34552.1 - 3e-14 53.6 0.3 9.3e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EEQ34560.1 - 3.8e-25 88.3 36.1 8.2e-15 54.3 7.4 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ34560.1 - 0.04 13.7 1.9 2.1 8.1 0.3 2.7 2 0 0 2 2 2 0 MFS_1 like family NVEALA PF14055.1 EEQ34560.1 - 4 7.2 6.0 4.6 7.0 0.3 2.8 3 0 0 3 3 3 0 NVEALA protein APH PF01636.18 EEQ34561.1 - 2.9e-11 43.5 0.0 7.2e-11 42.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EGF_CA PF07645.10 EEQ34563.1 - 2.4e-06 27.4 6.1 2.4e-06 27.4 4.2 1.7 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 EEQ34563.1 - 0.0026 17.6 5.9 0.0026 17.6 4.1 2.3 2 1 0 2 2 2 1 EGF domain cEGF PF12662.2 EEQ34563.1 - 0.0045 16.6 0.1 0.0045 16.6 0.1 2.1 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.22 EEQ34563.1 - 0.0065 16.4 5.2 0.026 14.4 3.5 2.1 1 1 0 1 1 1 1 EGF-like domain FXa_inhibition PF14670.1 EEQ34563.1 - 0.011 15.8 5.6 0.011 15.8 3.9 2.6 2 2 0 2 2 2 0 Coagulation Factor Xa inhibitory site MCM PF00493.18 EEQ34565.1 - 3.5e-135 450.0 0.0 6.1e-135 449.2 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEQ34565.1 - 2.9e-27 95.5 0.2 1.1e-26 93.6 0.1 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ34565.1 - 4e-07 29.4 0.0 5.5e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ34565.1 - 2.5e-05 24.0 0.0 7e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EEQ34565.1 - 0.07 13.5 0.1 0.35 11.3 0.0 2.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEQ34565.1 - 0.077 12.5 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ34565.1 - 0.14 12.1 3.0 20 5.0 0.3 3.5 3 1 0 4 4 4 0 AAA ATPase domain AAA PF00004.24 EEQ34566.1 - 8.1e-55 184.6 0.0 2.5e-43 147.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EEQ34566.1 - 1.7e-29 101.6 0.3 4e-29 100.4 0.2 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EEQ34566.1 - 2.9e-10 40.4 2.4 1.4e-05 25.2 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 EEQ34566.1 - 5.8e-07 29.3 0.8 0.00044 19.9 0.0 3.7 4 0 0 4 4 3 1 NACHT domain AAA_2 PF07724.9 EEQ34566.1 - 6.1e-07 29.5 0.0 0.026 14.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EEQ34566.1 - 6.5e-06 25.6 0.1 0.0099 15.3 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.1 EEQ34566.1 - 1e-05 25.6 0.5 0.3 11.2 0.0 3.7 2 2 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EEQ34566.1 - 3e-05 23.2 0.0 0.014 14.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEQ34566.1 - 3e-05 23.6 0.0 0.063 13.0 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EEQ34566.1 - 3.4e-05 24.6 0.0 0.19 12.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EEQ34566.1 - 4.2e-05 23.4 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEQ34566.1 - 0.00018 21.8 0.0 0.12 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EEQ34566.1 - 0.00029 20.5 0.1 0.9 9.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEQ34566.1 - 0.00059 18.9 0.0 0.78 8.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EEQ34566.1 - 0.00096 17.9 0.0 0.89 8.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 EEQ34566.1 - 0.0013 18.6 0.1 0.38 10.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EEQ34566.1 - 0.0013 18.1 2.9 5.5 6.3 0.1 4.0 2 2 1 4 4 4 0 AAA domain AAA_28 PF13521.1 EEQ34566.1 - 0.0028 17.6 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EEQ34566.1 - 0.0032 17.1 0.1 0.12 11.9 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EEQ34566.1 - 0.0065 15.4 0.2 0.097 11.6 0.0 2.3 2 1 1 3 3 2 1 KAP family P-loop domain RNA_helicase PF00910.17 EEQ34566.1 - 0.0091 16.1 0.0 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Sigma54_activ_2 PF14532.1 EEQ34566.1 - 0.0092 16.0 0.0 2.8 7.9 0.0 3.1 3 0 0 3 3 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EEQ34566.1 - 0.017 14.2 0.1 0.86 8.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 EEQ34566.1 - 0.021 14.0 0.3 1.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 EEQ34566.1 - 0.021 15.0 0.1 4.8 7.4 0.0 2.7 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 EEQ34566.1 - 0.027 13.3 0.1 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein SKI PF01202.17 EEQ34566.1 - 0.069 13.0 0.0 5 6.9 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.11 EEQ34566.1 - 0.083 12.1 0.1 9.1 5.4 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EEQ34566.1 - 0.085 11.9 0.1 12 4.9 0.0 2.4 2 0 0 2 2 2 0 KaiC APS_kinase PF01583.15 EEQ34566.1 - 0.11 12.1 0.1 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2075 PF09848.4 EEQ34566.1 - 0.17 10.8 0.0 12 4.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EEQ34566.1 - 0.17 11.3 0.6 5.7 6.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 EEQ34566.1 - 0.17 11.3 0.0 7.4 6.0 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EEQ34566.1 - 0.18 11.4 0.1 26 4.4 0.0 3.1 2 1 1 3 3 3 0 Archaeal ATPase Cytidylate_kin2 PF13189.1 EEQ34566.1 - 0.26 11.1 0.0 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family HisG PF01634.13 EEQ34567.1 - 7.4e-52 175.2 0.0 1.1e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EEQ34567.1 - 1.1e-26 92.5 0.1 2.5e-26 91.4 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EEQ34567.1 - 0.00098 18.7 0.1 0.0028 17.2 0.0 1.8 1 1 0 1 1 1 1 NMT1/THI5 like Ribosomal_S28e PF01200.13 EEQ34568.1 - 2.5e-33 113.6 0.7 2.6e-33 113.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.16 EEQ34569.1 - 3.8e-88 294.8 0.0 6.1e-88 294.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEQ34569.1 - 1.3e-36 126.3 0.4 3.2e-36 125.0 0.3 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEQ34569.1 - 1.2e-26 92.9 0.2 3.4e-26 91.4 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EEQ34569.1 - 4.9e-10 39.6 0.0 1.9e-09 37.6 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EEQ34569.1 - 3.2e-07 30.4 0.4 8.9e-07 29.0 0.3 1.7 1 0 0 1 1 1 1 MutS family domain IV Prenyltrans PF00432.16 EEQ34571.1 - 3.1e-47 157.8 10.8 7.5e-12 44.5 0.1 6.4 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEQ34571.1 - 1.4e-35 122.0 0.4 2.4e-12 47.2 0.0 3.4 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEQ34571.1 - 3.8e-09 36.5 0.0 0.0018 18.2 0.0 3.4 1 1 1 3 3 3 2 Prenyltransferase-like DUF3858 PF12970.2 EEQ34572.1 - 0.13 12.0 0.1 3.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3858) RhoGAP PF00620.22 EEQ34573.1 - 2e-16 59.9 0.0 3.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.7 EEQ34574.1 - 3.2e-56 189.3 2.7 4.8e-56 188.7 1.9 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.4 EEQ34575.1 - 2.2e-84 283.0 0.0 3.5e-84 282.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 PrpF PF04303.8 EEQ34578.1 - 1.4e-102 343.2 0.2 1.6e-102 343.0 0.2 1.0 1 0 0 1 1 1 1 PrpF protein Peptidase_C48 PF02902.14 EEQ34579.1 - 1e-15 57.9 1.7 4.8e-15 55.7 0.3 2.6 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RhoGEF PF00621.15 EEQ34580.1 - 2e-36 125.5 0.0 3.9e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EEQ34580.1 - 1.5e-06 27.9 0.0 0.013 15.0 0.0 2.6 2 0 0 2 2 2 2 BAR domain Telomerase_RBD PF12009.3 EEQ34581.1 - 1.9e-40 137.9 0.0 3.9e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EEQ34581.1 - 6.7e-15 55.0 0.0 9.7e-14 51.2 0.0 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aldo_ket_red PF00248.16 EEQ34582.1 - 4.6e-33 114.2 0.0 5.8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family IDO PF01231.13 EEQ34584.1 - 6.9e-106 354.2 0.0 2.4e-105 352.4 0.0 1.8 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EEQ34584.1 - 0.0066 15.0 0.0 0.032 12.7 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1864) Pkinase PF00069.20 EEQ34585.1 - 3.8e-19 68.8 0.0 4.7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34585.1 - 3.1e-12 46.1 0.0 4.1e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ34585.1 - 1.6e-06 27.3 0.0 2.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ34585.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RabGAP-TBC PF00566.13 EEQ34586.1 - 1.4e-19 70.3 0.0 2.6e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Proteasome PF00227.21 EEQ34587.1 - 1.6e-44 151.4 0.2 2e-44 151.1 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 EEQ34588.1 - 1.9e-36 125.6 8.4 1e-21 77.9 0.3 3.4 3 1 1 4 4 4 2 Cyclin Abhydrolase_5 PF12695.2 EEQ34589.1 - 5.3e-23 81.3 0.0 7.5e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ34589.1 - 4.8e-19 69.1 0.0 8.9e-18 65.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ34589.1 - 1.3e-07 31.4 0.0 2.1e-05 24.1 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ34589.1 - 6.4e-06 25.5 0.0 4.1e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 EEQ34589.1 - 5.9e-05 21.7 0.3 0.053 12.0 0.1 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EEQ34589.1 - 0.00012 21.8 0.0 0.012 15.3 0.0 2.4 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EEQ34589.1 - 0.00012 21.4 0.0 0.04 13.1 0.0 2.3 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EEQ34589.1 - 0.00017 21.0 0.3 0.1 12.0 0.0 2.5 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 EEQ34589.1 - 0.00027 20.4 0.0 0.00089 18.7 0.0 1.7 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EEQ34589.1 - 0.00048 19.7 0.0 0.00083 18.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EEQ34589.1 - 0.00079 19.0 0.1 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EEQ34589.1 - 0.0026 17.5 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 EEQ34589.1 - 0.0044 16.4 0.0 0.0079 15.6 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EEQ34589.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EEQ34589.1 - 0.048 13.8 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF818 PF05677.7 EEQ34589.1 - 0.049 12.3 0.0 0.069 11.8 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF676 PF05057.9 EEQ34589.1 - 0.088 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.3 EEQ34589.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.15 EEQ34589.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase ATP11 PF06644.6 EEQ34590.1 - 9.4e-87 290.8 0.0 1.1e-86 290.6 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Scytalone_dh PF02982.9 EEQ34590.1 - 0.043 13.3 0.1 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase Glyco_hydro_3 PF00933.16 EEQ34591.1 - 1.6e-60 204.6 0.0 2.2e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EEQ34591.1 - 1.1e-18 67.0 0.0 1.3e-09 37.9 0.0 2.8 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ34591.1 - 1.3e-15 57.2 0.0 2.4e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ34591.1 - 1.4e-11 44.5 0.0 1.2e-06 28.5 0.0 2.8 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ34591.1 - 4.5e-07 29.7 0.0 0.041 13.7 0.0 3.4 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 EEQ34591.1 - 3e-06 26.9 0.0 6.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_CG PF14542.1 EEQ34591.1 - 2.5e-05 24.0 0.1 0.0045 16.8 0.0 3.0 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EEQ34591.1 - 0.0014 18.3 0.0 0.023 14.4 0.0 2.4 2 0 0 2 2 2 1 FR47-like protein DUF3749 PF12568.3 EEQ34591.1 - 0.0077 15.8 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EEQ34591.1 - 0.012 15.5 0.0 4.8 7.1 0.0 3.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ34591.1 - 0.081 12.7 0.0 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEQ34591.1 - 0.086 12.9 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EEQ34593.1 - 1.1e-16 60.7 0.0 4.5e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34593.1 - 0.0001 21.5 0.1 0.2 10.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Aldo_ket_red PF00248.16 EEQ34594.1 - 9.6e-50 168.9 0.0 1.1e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_M14 PF00246.19 EEQ34595.1 - 1.8e-18 67.1 0.0 2.6e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 EEQ34595.1 - 0.0029 16.7 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.9 EEQ34595.1 - 0.049 12.5 0.1 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M36 PF02128.10 EEQ34596.1 - 8.7e-151 502.0 5.5 1.3e-150 501.5 3.8 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EEQ34596.1 - 3.3e-08 32.8 1.1 9.5e-08 31.4 0.8 1.9 1 1 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EEQ34596.1 - 0.055 13.5 0.2 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase MA superfamily adh_short PF00106.20 EEQ34597.1 - 3.3e-09 36.8 0.0 5.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ34597.1 - 1.2e-06 28.3 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ34597.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HSDR_N_2 PF13588.1 EEQ34598.1 - 0.0011 18.6 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) APH PF01636.18 EEQ34598.1 - 0.0021 17.8 1.4 0.0065 16.2 0.0 2.5 3 1 1 4 4 4 1 Phosphotransferase enzyme family Tropomyosin PF00261.15 EEQ34598.1 - 0.0026 16.8 4.4 0.0048 16.0 3.0 1.4 1 0 0 1 1 1 1 Tropomyosin Pkinase PF00069.20 EEQ34598.1 - 0.12 11.4 0.0 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain PGBA_C PF15437.1 EEQ34598.1 - 4.6 7.4 15.5 5.5 7.1 5.8 2.8 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Beta_elim_lyase PF01212.16 EEQ34599.1 - 5.6e-54 183.2 0.0 6.6e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EEQ34599.1 - 0.0057 14.9 0.0 0.0092 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GFA PF04828.9 EEQ34600.1 - 2.6e-17 62.5 0.3 3.4e-17 62.1 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme HNH_2 PF13391.1 EEQ34601.1 - 5.1e-12 45.3 0.0 1.9e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease FAD_binding_7 PF03441.9 EEQ34602.1 - 5e-87 291.6 0.7 9.5e-74 248.0 0.1 2.2 1 1 1 2 2 2 2 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EEQ34602.1 - 6.6e-39 133.3 0.3 1.4e-38 132.2 0.1 1.6 2 0 0 2 2 2 1 DNA photolyase Guanylin PF02058.10 EEQ34602.1 - 0.15 12.1 0.0 22 5.1 0.0 2.5 1 1 1 2 2 2 0 Guanylin precursor DUF1653 PF07866.6 EEQ34604.1 - 0.023 14.8 0.6 0.05 13.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1653) Glyco_hydro_18 PF00704.23 EEQ34605.1 - 1.6e-19 70.5 0.4 2.6e-19 69.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEQ34606.1 - 4.7e-05 23.1 1.2 0.0066 16.3 0.0 3.4 4 0 0 4 4 4 1 LysM domain Ski_Sno PF02437.12 EEQ34606.1 - 0.034 13.7 1.4 0.048 13.2 0.2 1.8 2 0 0 2 2 2 0 SKI/SNO/DAC family UPF0203 PF05254.7 EEQ34606.1 - 0.51 10.2 5.8 0.078 12.8 0.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Bromo_TP PF07524.8 EEQ34607.1 - 9.6e-11 41.2 0.0 1.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAFII55_N PF04658.8 EEQ34608.1 - 3.3e-51 173.0 0.0 5.6e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region Apc15p PF05841.6 EEQ34608.1 - 0.053 14.2 8.0 1.5 9.5 1.8 2.6 2 0 0 2 2 2 0 Apc15p protein SCHIP-1 PF10148.4 EEQ34608.1 - 0.13 11.6 3.4 0.23 10.8 2.4 1.4 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 BRO1 PF03097.13 EEQ34609.1 - 2.1e-07 30.0 0.1 3.2e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 BRO1-like domain DicB PF05358.6 EEQ34609.1 - 0.17 11.3 0.0 3.6 7.1 0.0 2.8 3 0 0 3 3 3 0 DicB protein NDUFB10 PF10249.4 EEQ34610.1 - 0.0013 18.9 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Glyco_transf_34 PF05637.7 EEQ34611.1 - 5.6e-64 215.9 0.0 8.1e-64 215.3 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Peptidase_M28 PF04389.12 EEQ34612.1 - 1e-16 61.2 0.0 1.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EEQ34612.1 - 6.4e-14 51.6 0.0 1.1e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EEQ34612.1 - 3.2e-06 26.7 0.1 2e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EEQ34612.1 - 0.0055 16.2 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EEQ34612.1 - 0.061 12.5 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Nicastrin Pkinase PF00069.20 EEQ34613.1 - 1.6e-67 227.3 0.0 2.2e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34613.1 - 5.2e-31 107.6 0.0 8.3e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EEQ34613.1 - 1.6e-09 37.7 0.1 1.5e-08 34.5 0.0 2.6 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EEQ34613.1 - 0.088 11.7 0.0 0.36 9.7 0.0 1.9 1 1 0 1 1 1 0 Kinase-like CN_hydrolase PF00795.17 EEQ34614.1 - 8.7e-32 109.9 0.1 1.1e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Beta_elim_lyase PF01212.16 EEQ34615.1 - 1.4e-65 221.3 0.0 1.8e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EEQ34615.1 - 0.072 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RNase_T PF00929.19 EEQ34617.1 - 1.1e-23 84.3 0.0 1.7e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease OPT PF03169.10 EEQ34618.1 - 3.1e-162 541.2 48.3 1.6e-89 301.0 13.9 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF4191 PF13829.1 EEQ34618.1 - 0.025 13.7 0.2 0.065 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Tweety PF04906.8 EEQ34618.1 - 0.2 10.0 2.1 0.33 9.2 1.4 1.2 1 0 0 1 1 1 0 Tweety YqjK PF13997.1 EEQ34618.1 - 2.9 8.1 6.2 14 5.9 0.1 3.6 4 0 0 4 4 4 0 YqjK-like protein DUF3093 PF11292.3 EEQ34618.1 - 8.2 6.2 10.8 1.3 8.7 3.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Glutaredoxin PF00462.19 EEQ34619.1 - 9.7e-18 63.9 0.0 8.1e-17 60.9 0.0 2.3 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EEQ34619.1 - 2.4e-12 46.4 0.0 8.2e-12 44.7 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EEQ34619.1 - 0.02 14.9 0.0 0.25 11.4 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like ArsC PF03960.10 EEQ34619.1 - 0.11 12.6 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 ArsC family TrbC_Ftype PF09673.5 EEQ34619.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein TauD PF02668.11 EEQ34620.1 - 5.4e-59 199.9 0.0 8.5e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EEQ34620.1 - 0.059 12.2 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 CsiD DUF971 PF06155.7 EEQ34620.1 - 0.093 13.1 0.5 0.44 11.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF971) Mito_carr PF00153.22 EEQ34621.1 - 1.3e-67 223.5 1.4 2e-21 75.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_4 PF02056.11 EEQ34621.1 - 0.13 11.6 0.1 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Tubulin PF00091.20 EEQ34622.1 - 3.1e-64 216.7 0.0 4.2e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEQ34622.1 - 6.2e-43 145.8 0.0 9.6e-43 145.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EEQ34622.1 - 0.0004 19.9 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.13 EEQ34623.1 - 1.1e-23 83.6 2.9 2.3e-23 82.6 2.0 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.1 EEQ34623.1 - 7.5e-05 21.8 0.0 0.00018 20.6 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 EEQ34623.1 - 8.5e-05 21.5 0.2 0.0002 20.4 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EEQ34623.1 - 0.00049 20.1 0.3 0.0013 18.8 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ34623.1 - 0.00089 18.9 0.0 0.0025 17.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain DUF2648 PF10855.3 EEQ34623.1 - 0.036 13.4 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) DUF3671 PF12420.3 EEQ34623.1 - 2.6 8.0 6.0 3.5 7.6 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function PAXIP1_C PF15364.1 EEQ34624.1 - 0.015 15.2 1.7 0.017 15.0 0.6 1.5 1 1 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein BDV_P40 PF06407.6 EEQ34624.1 - 0.046 12.5 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Borna disease virus P40 protein Herpes_BLLF1 PF05109.8 EEQ34624.1 - 0.43 8.4 5.9 0.51 8.2 4.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) ChlamPMP_M PF07548.6 EEQ34625.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain SNF2_N PF00176.18 EEQ34627.1 - 3.7e-27 94.8 0.0 5.2e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EEQ34627.1 - 5.3e-09 36.1 0.0 1.7e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ34627.1 - 0.0012 18.4 0.0 0.76 9.2 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase PDR_CDR PF06422.7 EEQ34630.1 - 1.6e-39 133.7 0.0 1.6e-34 117.6 0.0 2.5 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EEQ34630.1 - 7.2e-37 126.7 0.3 3.7e-17 62.9 0.0 3.1 4 0 0 4 4 3 2 ABC transporter ABC2_membrane PF01061.19 EEQ34630.1 - 2.4e-28 98.7 29.5 1.5e-12 47.1 4.4 4.7 3 2 1 4 4 4 3 ABC-2 type transporter ABC_trans_N PF14510.1 EEQ34630.1 - 3.8e-23 81.3 0.0 8.6e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EEQ34630.1 - 9.7e-07 28.3 0.0 0.00017 21.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEQ34630.1 - 1.4e-06 28.2 0.0 9.1e-05 22.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEQ34630.1 - 9.7e-06 24.8 0.1 0.0021 17.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EEQ34630.1 - 7.7e-05 23.0 0.0 0.031 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ34630.1 - 0.00032 20.1 1.3 0.031 13.8 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EEQ34630.1 - 0.00035 20.0 1.1 0.0099 15.3 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EEQ34630.1 - 0.0015 19.3 0.0 0.29 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ34630.1 - 0.0016 18.5 1.4 0.17 11.8 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ34630.1 - 0.0022 18.1 0.2 0.77 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EEQ34630.1 - 0.027 13.6 0.0 2.2 7.4 0.0 3.0 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EEQ34630.1 - 0.037 13.6 2.0 1.8 8.1 0.1 2.8 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.1 EEQ34630.1 - 0.047 13.6 0.1 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEQ34630.1 - 0.056 13.1 0.9 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 EEQ34630.1 - 0.066 13.1 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EEQ34630.1 - 0.076 12.9 0.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 EEQ34630.1 - 0.095 12.2 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EEQ34630.1 - 0.16 11.6 0.0 21 4.7 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 EEQ34630.1 - 0.19 11.4 0.5 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EEQ34630.1 - 0.21 11.0 0.5 1.7 8.0 0.0 2.4 3 0 0 3 3 2 0 FtsK/SpoIIIE family zf-C2H2_4 PF13894.1 EEQ34633.1 - 0.047 14.0 0.4 0.047 14.0 0.3 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ34633.1 - 2.3 8.7 14.3 5.5 7.5 0.2 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Ribul_P_3_epim PF00834.14 EEQ34634.1 - 1.5e-62 210.2 0.0 1.3e-61 207.2 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 EEQ34634.1 - 0.099 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family SH3BGR PF04908.10 EEQ34635.1 - 0.00054 19.8 0.4 0.0043 16.9 0.0 2.5 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein zf-BED PF02892.10 EEQ34636.1 - 0.0043 16.7 4.7 0.37 10.5 0.6 2.5 2 0 0 2 2 2 2 BED zinc finger DUF3615 PF12274.3 EEQ34636.1 - 0.32 11.3 2.3 0.89 9.9 1.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3615) RAP1 PF07218.6 EEQ34636.1 - 3.4 5.6 6.2 6 4.8 4.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Methyltransf_11 PF08241.7 EEQ34637.1 - 3.1e-06 27.5 0.0 6.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ34637.1 - 0.031 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 EEQ34638.1 - 5.5e-15 54.6 1.1 7.6e-15 54.2 0.8 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EEQ34638.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.1 EEQ34638.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DRMBL PF07522.9 EEQ34639.1 - 1.3e-34 118.5 0.0 2.5e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EEQ34639.1 - 2.1e-10 40.4 0.1 4.1e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEQ34639.1 - 0.12 12.0 2.5 0.39 10.3 1.7 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily FAD_binding_4 PF01565.18 EEQ34640.1 - 7.5e-19 67.5 0.8 1.2e-18 66.9 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Nbl1_Borealin_N PF10444.4 EEQ34641.1 - 3.1e-22 77.6 5.4 6.5e-22 76.6 3.7 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 EEQ34642.1 - 1.7e-06 28.2 0.0 2.1e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EEQ34642.1 - 0.0011 18.3 0.3 0.0036 16.7 0.2 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Ssl1 PF04056.9 EEQ34642.1 - 0.0036 16.9 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like Val_tRNA-synt_C PF10458.4 EEQ34642.1 - 0.036 14.1 5.4 0.087 12.9 3.7 1.6 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Phage_Gp23 PF10669.4 EEQ34642.1 - 0.3 11.1 3.0 0.67 10.0 2.1 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Sybindin PF04099.7 EEQ34643.1 - 2.6e-46 156.8 0.0 3.4e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EEQ34643.1 - 3.6e-07 30.1 0.0 7.4e-07 29.0 0.0 1.4 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region UQ_con PF00179.21 EEQ34644.1 - 1.2e-24 86.3 0.0 7.4e-11 41.6 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ34644.1 - 8.4e-06 25.5 0.0 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic E2 family B FDC-SP PF15215.1 EEQ34644.1 - 0.022 15.0 0.1 0.049 13.9 0.1 1.6 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide ketoacyl-synt PF00109.21 EEQ34647.1 - 1.2e-75 254.3 0.3 2e-75 253.5 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEQ34647.1 - 3e-38 130.3 0.0 7e-38 129.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EEQ34647.1 - 5.4e-26 91.6 0.0 9.3e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 EEQ34647.1 - 1.4e-24 86.1 7.8 1.1e-12 48.0 0.6 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EEQ34647.1 - 2.8e-15 56.2 0.0 6.3e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_3 PF07859.8 EEQ34647.1 - 1.4e-12 47.7 0.0 2e-10 40.6 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ34647.1 - 3.2e-12 46.4 0.0 1.4e-09 37.8 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ34647.1 - 1e-08 34.6 0.0 2.9e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEQ34647.1 - 3.9e-08 33.4 0.1 1.5e-06 28.2 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 EEQ34647.1 - 9.1e-07 28.1 1.0 1.6e-06 27.3 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain DLH PF01738.13 EEQ34647.1 - 0.017 14.3 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EEQ34647.1 - 0.019 14.3 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase COesterase PF00135.23 EEQ34647.1 - 0.022 13.4 0.0 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Peptidase_S15 PF02129.13 EEQ34647.1 - 0.15 11.4 0.0 3 7.2 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) FGE-sulfatase PF03781.11 EEQ34648.1 - 8.2e-31 107.2 0.1 1.3e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EEQ34648.1 - 1.4e-08 35.1 0.4 3e-08 34.0 0.3 1.6 1 0 0 1 1 1 1 DinB superfamily Methyltransf_18 PF12847.2 EEQ34648.1 - 5.1e-08 33.4 0.0 1.8e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ34648.1 - 5.2e-07 29.9 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ34648.1 - 0.00087 19.7 0.0 0.0046 17.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ34648.1 - 0.041 13.4 0.0 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ34648.1 - 0.055 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 EEQ34648.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Gln-synt_C PF00120.19 EEQ34649.1 - 8.4e-38 129.9 0.0 1.8e-37 128.9 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain IDO PF01231.13 EEQ34650.1 - 2.3e-40 138.3 0.0 4.4e-40 137.3 0.0 1.5 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase APH PF01636.18 EEQ34651.1 - 5.8e-13 49.1 0.0 3.4e-12 46.6 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family MtrG PF04210.8 EEQ34651.1 - 0.12 12.0 0.3 0.98 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G 3Beta_HSD PF01073.14 EEQ34652.1 - 4e-46 156.9 0.0 5.2e-41 140.1 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEQ34652.1 - 1.4e-16 60.6 0.1 1.1e-15 57.7 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEQ34652.1 - 1.9e-12 46.6 0.0 2.1e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EEQ34652.1 - 0.00013 21.0 0.0 0.00054 18.9 0.0 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEQ34652.1 - 0.00099 19.1 0.0 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Pkinase PF00069.20 EEQ34653.1 - 8.3e-61 205.3 0.0 1e-39 136.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34653.1 - 9.1e-29 100.3 0.0 5e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EEQ34653.1 - 9.8e-12 44.8 0.0 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EEQ34653.1 - 7.9e-08 31.6 0.0 4.7e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ34653.1 - 1.4e-05 24.9 0.0 0.0056 16.4 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEQ34653.1 - 0.0045 16.0 0.0 0.0088 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 EEQ34653.1 - 0.0049 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EEQ34653.1 - 0.028 14.2 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 EEQ34653.1 - 0.13 11.1 0.1 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 eIF-3_zeta PF05091.7 EEQ34654.1 - 1.5e-187 624.3 0.0 1.8e-187 624.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med9 PF07544.8 EEQ34655.1 - 0.11 12.2 5.2 0.33 10.7 2.5 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.16 EEQ34655.1 - 0.11 12.4 15.5 3 7.8 10.7 2.5 1 1 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.12 EEQ34655.1 - 7.6 6.9 13.3 1.1e+02 3.1 9.2 2.5 1 1 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EEQ34655.1 - 9.3 6.1 14.7 0.51 10.1 3.4 2.6 2 0 0 2 2 2 0 Basic region leucine zipper F-box-like PF12937.2 EEQ34656.1 - 0.0097 15.6 0.1 0.045 13.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 EEQ34656.1 - 0.019 14.6 0.1 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain DUF2957 PF11170.3 EEQ34656.1 - 0.26 9.8 0.0 0.38 9.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) DUF3552 PF12072.3 EEQ34658.1 - 0.00095 18.4 1.5 0.0012 18.1 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF390 PF04094.9 EEQ34658.1 - 0.014 13.5 7.3 0.017 13.2 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Attachment_P66 PF11263.3 EEQ34658.1 - 0.1 11.6 0.1 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 DUF4187 PF13821.1 EEQ34660.1 - 4.6e-22 77.3 0.0 1.2e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 EEQ34660.1 - 8.9e-22 77.1 0.4 8.9e-22 77.1 0.3 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EEQ34660.1 - 5.2e-10 39.8 0.1 1.1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 CBFB_NFYA PF02045.10 EEQ34661.1 - 1e-30 106.0 4.1 1.8e-30 105.2 2.9 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 EEQ34661.1 - 0.061 12.2 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Kinesin PF00225.18 EEQ34662.1 - 3.5e-111 371.1 0.0 5.1e-111 370.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EEQ34662.1 - 1e-42 145.1 0.0 1.9e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EEQ34662.1 - 4.8e-07 29.7 0.3 4.8e-07 29.7 0.2 2.0 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.21 EEQ34662.1 - 3.1e-06 27.2 0.2 3.7e-05 23.7 0.1 2.9 3 0 0 3 3 3 1 FHA domain PH PF00169.24 EEQ34662.1 - 3.7e-06 27.0 0.0 1.2e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 PH domain 3-dmu-9_3-mt PF06983.8 EEQ34663.1 - 2.1e-39 134.4 0.1 3.1e-39 133.8 0.1 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DSX_dimer PF08828.5 EEQ34663.1 - 0.072 12.6 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Doublesex dimerisation domain Phosphodiest PF01663.17 EEQ34664.1 - 1.4e-83 281.2 0.1 1.9e-83 280.8 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEQ34664.1 - 0.00014 21.1 0.0 0.2 10.8 0.0 2.2 1 1 0 2 2 2 2 Sulfatase PglZ PF08665.7 EEQ34664.1 - 0.00043 19.9 0.0 0.015 14.9 0.0 2.4 2 0 0 2 2 2 1 PglZ domain IFT57 PF10498.4 EEQ34665.1 - 0.044 12.5 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Zn_clus PF00172.13 EEQ34667.1 - 0.0047 16.8 2.0 0.013 15.3 1.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EEQ34668.1 - 1e-67 228.3 0.2 2e-67 227.3 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEQ34668.1 - 1.4e-55 187.7 0.0 5.9e-55 185.7 0.0 2.2 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EEQ34668.1 - 2e-53 181.5 0.0 3.8e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EEQ34668.1 - 1.5e-49 169.0 0.0 2.7e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EEQ34668.1 - 3.9e-44 150.5 0.6 1.4e-43 148.7 0.0 2.4 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEQ34668.1 - 1e-36 125.3 0.3 3.1e-36 123.8 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EEQ34668.1 - 3e-18 66.0 0.0 1.3e-17 64.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EEQ34668.1 - 1e-14 54.1 0.0 4e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EEQ34668.1 - 2.6e-12 46.7 0.0 8.2e-12 45.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EEQ34668.1 - 4.9e-11 43.6 0.0 1.7e-09 38.6 0.0 3.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EEQ34668.1 - 7.6e-08 32.7 0.0 2.9e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ34668.1 - 1.8e-07 30.5 0.0 4.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EEQ34668.1 - 2.3e-07 31.3 0.0 1.4e-06 28.8 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EEQ34668.1 - 9.8e-07 28.9 0.1 3e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EEQ34668.1 - 2.3e-06 27.2 0.0 5.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EEQ34668.1 - 0.00094 18.2 0.2 0.0022 17.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 EEQ34668.1 - 0.0018 18.0 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PCMT PF01135.14 EEQ34668.1 - 0.24 10.9 0.2 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.17 EEQ34669.1 - 5.2e-44 150.5 0.0 2.5e-25 88.9 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 FAD_binding_3 PF01494.14 EEQ34670.1 - 6.6e-21 74.7 0.1 9.6e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEQ34670.1 - 1.6e-09 37.1 0.6 0.0013 17.7 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EEQ34670.1 - 2.6e-07 30.0 0.9 0.0025 16.9 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EEQ34670.1 - 2.3e-06 26.7 1.5 0.035 13.0 0.1 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEQ34670.1 - 6.8e-06 26.0 0.3 2.3e-05 24.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEQ34670.1 - 2.2e-05 24.7 1.4 0.0004 20.7 0.2 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ34670.1 - 0.00063 18.7 1.3 0.00098 18.0 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EEQ34670.1 - 0.0028 16.3 0.9 0.014 14.0 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EEQ34670.1 - 0.0047 16.8 0.1 0.0088 15.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ34670.1 - 0.024 14.7 1.9 0.15 12.0 0.3 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ34670.1 - 0.058 11.8 0.3 0.27 9.6 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EEQ34670.1 - 0.068 12.0 0.5 0.14 11.0 0.4 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 EEQ34670.1 - 0.071 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EEQ34670.1 - 0.15 11.8 1.4 16 5.2 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding ABC_membrane PF00664.18 EEQ34671.1 - 7e-87 291.3 41.3 3.5e-46 157.8 9.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ34671.1 - 1.5e-67 226.0 0.0 1.3e-32 112.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ34671.1 - 5e-14 52.0 0.0 9.7e-05 21.6 0.0 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ34671.1 - 7.2e-13 49.1 0.9 0.014 15.4 0.1 4.3 2 2 1 3 3 3 3 AAA domain AAA_29 PF13555.1 EEQ34671.1 - 3.9e-08 32.7 0.4 0.00048 19.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EEQ34671.1 - 2e-07 29.9 3.0 0.0077 14.8 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EEQ34671.1 - 9.1e-07 29.7 0.1 0.09 13.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ34671.1 - 3.1e-06 27.2 1.8 0.021 14.8 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EEQ34671.1 - 4.5e-06 25.9 0.0 0.18 11.0 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEQ34671.1 - 2.7e-05 23.6 0.2 0.2 11.0 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 EEQ34671.1 - 3.3e-05 24.0 1.2 0.79 9.8 0.0 3.8 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EEQ34671.1 - 0.00057 19.7 2.9 0.59 10.0 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EEQ34671.1 - 0.0019 17.6 1.3 5.2 6.4 0.1 4.1 4 0 0 4 4 4 1 AAA-like domain AAA_33 PF13671.1 EEQ34671.1 - 0.002 18.0 0.1 2.2 8.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEQ34671.1 - 0.0025 18.1 0.0 4 7.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EEQ34671.1 - 0.0055 17.0 0.0 0.34 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEQ34671.1 - 0.0081 15.2 0.3 0.8 8.7 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_28 PF13521.1 EEQ34671.1 - 0.0092 15.9 0.6 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEQ34671.1 - 0.053 13.2 0.0 16 5.1 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EEQ34671.1 - 0.057 13.1 0.2 17 5.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EEQ34671.1 - 0.059 13.3 0.0 16 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EEQ34671.1 - 0.11 12.6 0.1 8.5 6.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.15 EEQ34671.1 - 0.3 9.7 0.1 6.8 5.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Transferase PF02458.10 EEQ34672.1 - 2.2e-12 46.2 0.0 1.9e-08 33.2 0.0 2.5 3 0 0 3 3 3 2 Transferase family FSH1 PF03959.8 EEQ34673.1 - 1.5e-28 99.7 0.0 8.6e-27 93.9 0.0 2.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EEQ34673.1 - 2.6e-09 37.2 0.0 3.2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ34673.1 - 0.0024 17.4 0.0 0.0053 16.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEQ34673.1 - 0.0041 16.5 0.2 0.5 9.7 0.1 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEQ34673.1 - 0.074 12.8 0.0 0.33 10.7 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.17 EEQ34674.1 - 4.4e-34 117.8 0.0 5.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Herpes_US9 PF06072.6 EEQ34676.1 - 0.0061 16.3 1.8 0.016 15.0 1.2 1.7 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 DUF3328 PF11807.3 EEQ34676.1 - 0.074 12.7 1.3 2.7 7.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) HLH PF00010.21 EEQ34677.1 - 4.1e-16 58.4 2.2 5.4e-16 58.0 0.5 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF972 PF06156.8 EEQ34677.1 - 1.8 8.9 6.7 0.88 9.9 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 EEQ34677.1 - 2.6 6.9 15.1 0.59 9.0 6.0 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 EEQ34677.1 - 2.9 7.9 17.0 1.2 9.0 5.4 3.1 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Ofd1_CTDD PF10637.4 EEQ34680.1 - 1.1e-95 319.8 0.1 1.8e-91 306.0 0.3 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EEQ34680.1 - 6.1e-15 55.5 0.0 1.4e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EEQ34680.1 - 0.0066 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 EEQ34681.1 - 3.3e-09 36.8 0.0 1.1e-08 35.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family COesterase PF00135.23 EEQ34683.1 - 4.1e-96 322.8 0.0 5.6e-96 322.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ34683.1 - 3.7e-06 26.6 0.2 8.6e-05 22.2 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ34683.1 - 0.011 14.9 0.2 0.019 14.1 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4397 PF14344.1 EEQ34687.1 - 0.031 14.5 0.1 0.14 12.5 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4397) p450 PF00067.17 EEQ34689.1 - 2.2e-70 237.4 0.0 3e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.17 EEQ34689.1 - 0.0085 15.9 0.5 0.018 14.8 0.4 1.5 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ComX PF05952.7 EEQ34689.1 - 0.12 11.9 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX HNH_2 PF13391.1 EEQ34691.1 - 7.8e-19 67.2 0.0 1e-17 63.6 0.0 2.5 2 0 0 2 2 2 1 HNH endonuclease HNH_2 PF13391.1 EEQ34692.1 - 2.9e-14 52.6 1.1 4.6e-14 51.9 0.1 1.8 2 0 0 2 2 2 1 HNH endonuclease RhoGAP PF00620.22 EEQ34695.1 - 2.6e-33 114.7 0.1 5.4e-33 113.7 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EEQ34695.1 - 1.2e-28 98.8 34.8 3e-12 46.4 4.6 4.9 5 0 0 5 5 5 4 LIM domain AMP-binding PF00501.23 EEQ34696.1 - 6e-69 232.4 0.0 9.5e-69 231.7 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ34696.1 - 6.1e-06 27.0 0.0 1.4e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNA_pol_Rpb4 PF03874.11 EEQ34697.1 - 8.7e-24 83.7 2.4 1.1e-23 83.4 1.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF4102 PF13356.1 EEQ34697.1 - 0.052 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) DUF2312 PF10073.4 EEQ34697.1 - 0.096 12.0 0.7 0.32 10.3 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Met_10 PF02475.11 EEQ34698.1 - 4.7e-67 225.4 0.0 6.6e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein zf-CCHC_3 PF13917.1 EEQ34700.1 - 4.9 6.9 7.8 14 5.4 0.8 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-GRF PF06839.7 EEQ34701.1 - 8.9e-12 44.7 4.5 1.8e-11 43.7 3.1 1.6 1 0 0 1 1 1 1 GRF zinc finger DUF1192 PF06698.6 EEQ34701.1 - 0.47 10.2 4.1 1.5 8.6 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3818 PF12825.2 EEQ34702.1 - 1.8e-128 428.0 9.8 1.4e-85 287.0 1.5 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EEQ34702.1 - 5.9e-43 145.7 0.2 1.3e-42 144.6 0.1 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EEQ34702.1 - 3.3e-12 46.2 0.1 1.2e-10 41.1 0.0 3.3 3 1 0 3 3 3 1 PX domain Aldo_ket_red PF00248.16 EEQ34703.1 - 5.7e-56 189.4 0.0 6.8e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TnpV PF14198.1 EEQ34703.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Hydrolase_6 PF13344.1 EEQ34704.1 - 1.5e-20 72.9 0.0 4e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ34704.1 - 1.1e-15 57.0 0.0 2.6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EEQ34704.1 - 0.0032 17.7 0.0 1.5 9.0 0.0 2.8 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ34704.1 - 0.053 13.9 0.0 0.47 10.8 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Apt1 PF10351.4 EEQ34704.1 - 0.15 10.8 0.7 0.23 10.2 0.0 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Crystall PF00030.14 EEQ34705.1 - 0.0031 17.3 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall_3 PF08964.5 EEQ34705.1 - 0.036 13.7 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF791 PF05631.9 EEQ34706.1 - 8.3e-62 208.9 4.4 1.2e-61 208.4 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EEQ34706.1 - 5.4e-22 77.9 22.2 1.3e-21 76.7 15.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ34706.1 - 3.8e-07 29.0 6.0 3.8e-07 29.0 4.1 3.2 3 1 1 4 4 4 2 Sugar (and other) transporter V_ATPase_I PF01496.14 EEQ34706.1 - 0.18 9.6 0.5 0.29 8.9 0.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UAA PF08449.6 EEQ34707.1 - 8.3e-69 231.8 10.7 1.6e-68 230.8 7.4 1.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEQ34707.1 - 0.00069 19.2 11.7 0.00069 19.2 8.1 3.0 2 2 0 2 2 2 1 Triose-phosphate Transporter family DUF3681 PF12442.3 EEQ34707.1 - 0.089 12.9 2.2 0.37 10.9 1.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) EamA PF00892.15 EEQ34707.1 - 9.1 6.3 32.3 0.13 12.3 4.1 3.1 4 0 0 4 4 4 0 EamA-like transporter family Rad17 PF03215.10 EEQ34708.1 - 9.2e-55 186.2 0.0 1.6e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EEQ34708.1 - 0.0009 20.0 0.1 0.0059 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ34708.1 - 0.0026 17.7 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EEQ34708.1 - 0.0028 16.5 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EEQ34708.1 - 0.0056 16.3 0.1 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EEQ34708.1 - 0.013 15.7 1.8 0.32 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EEQ34708.1 - 0.015 15.0 0.0 0.043 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EEQ34708.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEQ34708.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ34708.1 - 0.069 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEQ34708.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EEQ34708.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EEQ34708.1 - 0.21 11.2 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ELMO_CED12 PF04727.8 EEQ34709.1 - 4.8e-50 169.4 0.1 8.2e-50 168.6 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EEQ34709.1 - 1.2e-06 28.2 0.8 1.4e-05 24.8 0.6 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) FliD_N PF02465.13 EEQ34709.1 - 0.02 15.2 0.2 0.051 13.9 0.1 1.7 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF4257 PF14074.1 EEQ34709.1 - 0.065 12.8 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) DUF1752 PF08550.5 EEQ34710.1 - 1.2e-08 34.3 2.9 2.6e-08 33.3 2.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUI1 PF01253.17 EEQ34712.1 - 3e-22 78.2 0.2 5.4e-22 77.3 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EEQ34712.1 - 0.00098 18.9 0.1 0.0018 18.1 0.1 1.4 1 0 0 1 1 1 1 Transposon-encoded protein TnpV SRP14 PF02290.10 EEQ34712.1 - 0.029 14.2 0.2 0.053 13.4 0.2 1.5 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Cgr1 PF03879.9 EEQ34714.1 - 1.3e-38 131.4 31.7 1.5e-38 131.2 22.0 1.0 1 0 0 1 1 1 1 Cgr1 family CAF-1_p150 PF11600.3 EEQ34714.1 - 0.067 12.5 22.5 0.08 12.3 15.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PRP1_N PF06424.7 EEQ34714.1 - 0.2 11.9 10.1 0.26 11.5 7.0 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Vfa1 PF08432.5 EEQ34714.1 - 4.2 7.3 14.8 5.3 7.0 10.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mito_carr PF00153.22 EEQ34715.1 - 4.3e-67 221.8 0.6 2e-23 81.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.17 EEQ34717.1 - 3.5e-15 55.5 0.8 4e-15 55.2 0.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EEQ34717.1 - 4.3e-07 29.9 0.0 5.9e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EEQ34717.1 - 9e-05 21.9 2.6 0.00031 20.2 0.1 2.0 1 1 1 2 2 2 1 A distinct subfamily of CDD/CDA-like deaminases Transp_cyt_pur PF02133.10 EEQ34718.1 - 1.9e-95 319.9 33.7 2.7e-95 319.5 23.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1049 PF06305.6 EEQ34718.1 - 0.063 12.7 0.1 15 5.1 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Polysacc_deac_1 PF01522.16 EEQ34719.1 - 4.7e-15 55.3 0.0 7.9e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase TFIIA PF03153.8 EEQ34719.1 - 2.3 8.0 8.3 3.2 7.5 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EEQ34719.1 - 7.5 5.8 15.1 10 5.3 10.4 1.2 1 0 0 1 1 1 0 Vta1 like BNR PF02012.15 EEQ34720.1 - 1.7e-09 36.0 23.9 0.39 10.7 0.1 9.8 9 0 0 9 9 9 5 BNR/Asp-box repeat BNR_2 PF13088.1 EEQ34720.1 - 1.6e-08 34.1 0.7 0.069 12.4 0.0 5.6 4 2 1 5 5 5 4 BNR repeat-like domain TFIIS_M PF07500.9 EEQ34723.1 - 7.2e-30 103.4 0.6 1.6e-29 102.2 0.1 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EEQ34723.1 - 1.2e-18 66.4 4.5 1.9e-18 65.8 3.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EEQ34723.1 - 8.3e-15 54.0 0.5 1.8e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Flavodoxin_3 PF12641.2 EEQ34723.1 - 0.019 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Baculo_LEF5_C PF11792.3 EEQ34723.1 - 0.027 13.8 1.3 0.063 12.6 0.9 1.6 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Chordopox_A33R PF05966.7 EEQ34723.1 - 0.028 13.1 0.0 0.069 11.9 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Cytochrome_C554 PF13435.1 EEQ34723.1 - 0.86 9.6 5.1 0.26 11.3 1.3 1.8 2 0 0 2 2 2 0 Cytochrome c554 and c-prime Cut8_N PF14482.1 EEQ34724.1 - 0.047 13.6 17.9 0.037 14.0 6.2 3.5 2 2 1 3 3 3 0 Cut8 proteasome-binding domain zf-C3HC4_2 PF13923.1 EEQ34724.1 - 1.3 9.0 13.0 5.6 7.0 0.7 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prenyltransf PF01255.14 EEQ34725.1 - 0.049 12.7 0.0 0.18 10.9 0.0 1.9 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase ATP_Ca_trans_C PF12424.3 EEQ34725.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Plasma membrane calcium transporter ATPase C terminal Sec10 PF07393.6 EEQ34726.1 - 5e-237 788.6 0.0 5.8e-237 788.3 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MBOAT_2 PF13813.1 EEQ34727.1 - 4.8e-17 61.8 0.4 1.3e-16 60.4 0.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family LRR_6 PF13516.1 EEQ34728.1 - 7e-12 44.1 3.2 0.039 14.0 0.0 7.9 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EEQ34728.1 - 2.8e-09 36.3 4.7 0.0035 16.9 0.2 5.1 3 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEQ34728.1 - 9.8e-07 27.9 3.8 44 4.6 0.0 7.5 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_7 PF13504.1 EEQ34728.1 - 0.00026 20.6 0.2 2.7e+02 2.5 0.0 6.7 7 0 0 7 7 7 0 Leucine rich repeat LRR_8 PF13855.1 EEQ34728.1 - 0.00047 19.8 4.0 2.8 7.7 0.0 5.2 4 2 0 4 4 4 1 Leucine rich repeat Pilt PF15453.1 EEQ34728.1 - 1 9.0 6.1 1.6 8.3 4.2 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Nop14 PF04147.7 EEQ34728.1 - 2.7 5.7 17.6 3.6 5.3 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family COX17 PF05051.8 EEQ34729.1 - 5.3e-20 71.1 4.8 6.4e-20 70.9 3.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EEQ34729.1 - 0.029 14.1 4.8 0.047 13.4 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Alg6_Alg8 PF03155.10 EEQ34730.1 - 1.5e-128 429.6 20.9 6.7e-80 269.1 4.1 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.17 EEQ34731.1 - 4.1e-40 135.2 0.1 8e-19 67.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ34731.1 - 3.9e-35 119.6 0.0 4.3e-17 61.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ34731.1 - 5.6e-19 67.7 0.0 1.8e-08 34.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EEQ34731.1 - 2.4 6.5 57.6 3.7 5.9 39.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CENP-T PF15511.1 EEQ34731.1 - 3.8 6.6 51.3 1 8.5 32.9 1.9 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Herpes_pp38 PF04846.8 EEQ34732.1 - 0.056 12.7 0.1 0.096 12.0 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein NMT1 PF09084.6 EEQ34733.1 - 6.7e-78 261.2 0.0 8.6e-78 260.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EEQ34733.1 - 9.6e-10 38.2 0.5 0.0026 17.1 0.0 3.3 2 1 0 3 3 3 3 NMT1-like family Ribosomal_L37 PF08561.5 EEQ34734.1 - 7.4e-28 95.9 3.6 1.2e-26 92.0 2.5 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 tRNA-synt_2b PF00587.20 EEQ34736.1 - 3.5e-65 218.8 0.0 6.6e-65 217.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ34736.1 - 3.6e-22 78.1 0.0 1.4e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain MFS_1 PF07690.11 EEQ34737.1 - 7.2e-28 97.3 31.2 7.5e-27 93.9 11.3 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4191 PF13829.1 EEQ34737.1 - 0.0082 15.2 2.4 0.046 12.8 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4191) OATP PF03137.15 EEQ34737.1 - 0.03 12.3 8.6 0.013 13.5 1.1 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Cpn60_TCP1 PF00118.19 EEQ34738.1 - 8.8e-124 413.7 12.6 1.1e-123 413.4 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 EEQ34738.1 - 0.029 14.2 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) AAA PF00004.24 EEQ34739.1 - 4.8e-41 140.0 0.0 8.2e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ34739.1 - 5e-06 26.6 0.0 0.00059 19.9 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EEQ34739.1 - 5e-05 23.0 0.0 0.00026 20.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEQ34739.1 - 0.00019 21.4 0.1 0.00082 19.4 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EEQ34739.1 - 0.00024 21.0 0.0 0.00059 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EEQ34739.1 - 0.0024 16.8 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EEQ34739.1 - 0.0032 18.2 0.1 0.013 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ34739.1 - 0.009 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEQ34739.1 - 0.01 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EEQ34739.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EEQ34739.1 - 0.026 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEQ34739.1 - 0.032 14.3 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EEQ34739.1 - 0.036 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EEQ34739.1 - 0.057 13.0 0.1 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EEQ34739.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEQ34739.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EEQ34739.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EEQ34739.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEQ34739.1 - 0.15 11.2 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FAD_binding_2 PF00890.19 EEQ34740.1 - 6.6e-126 420.5 3.8 8.3e-126 420.1 2.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EEQ34740.1 - 4e-47 159.2 0.9 6e-47 158.7 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EEQ34740.1 - 6e-07 29.5 0.0 0.0015 18.4 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEQ34740.1 - 6.2e-06 25.3 1.1 0.011 14.5 1.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EEQ34740.1 - 1.4e-05 24.3 0.1 0.015 14.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EEQ34740.1 - 0.00012 21.0 1.2 0.0026 16.7 0.6 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEQ34740.1 - 0.0048 16.0 0.4 0.011 14.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EEQ34740.1 - 0.19 10.1 1.7 0.83 8.0 0.6 2.4 3 0 0 3 3 3 0 HI0933-like protein DPPIV_N PF00930.16 EEQ34741.1 - 1.5e-110 369.1 0.7 2e-110 368.7 0.5 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EEQ34741.1 - 2.7e-55 186.8 4.8 2.7e-55 186.8 3.3 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ34741.1 - 5.6e-10 39.1 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EEQ34741.1 - 1.5e-07 31.1 0.9 6.7e-07 29.0 0.2 2.2 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EEQ34741.1 - 2.6e-06 27.4 0.0 1.7e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family PBP1_TM PF14812.1 EEQ34741.1 - 0.003 17.8 0.0 0.0072 16.6 0.0 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_2 PF02230.11 EEQ34741.1 - 0.024 14.0 0.6 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 EEQ34741.1 - 0.15 10.3 0.0 0.95 7.6 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PI-PLC-X PF00388.14 EEQ34742.1 - 1.6e-49 167.0 3.1 7.5e-36 122.7 0.0 3.0 3 0 0 3 3 3 2 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EEQ34742.1 - 5e-37 126.4 0.0 1e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain HECT_2 PF09814.4 EEQ34743.1 - 1.4e-27 96.3 0.0 1.8e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding HECT_2 PF09814.4 EEQ34744.1 - 9e-25 87.1 0.0 1.1e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GVQW PF13900.1 EEQ34745.1 - 2.6 8.0 5.4 1.6 8.7 1.2 2.4 2 0 0 2 2 2 0 Putative binding domain DUF4243 PF14027.1 EEQ34746.1 - 2.1e-74 250.9 0.0 2.6e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) TPR_10 PF13374.1 EEQ34747.1 - 2.5e-46 154.3 14.8 7.3e-11 41.6 0.1 8.3 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ34747.1 - 4e-43 145.2 6.9 1.8e-15 56.6 0.7 5.7 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ34747.1 - 1.4e-13 49.6 14.3 0.0088 15.8 0.0 6.5 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ34747.1 - 3.2e-10 39.4 16.8 0.0048 16.5 0.2 5.2 4 1 0 5 5 5 4 TPR repeat TPR_7 PF13176.1 EEQ34747.1 - 4.8e-10 38.4 14.2 0.0084 15.8 0.0 7.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ34747.1 - 5.3e-10 39.6 5.8 0.15 12.7 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ34747.1 - 4.2e-09 35.6 13.5 0.0011 18.4 0.1 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EEQ34747.1 - 2.8e-07 30.5 1.4 0.0002 21.4 0.1 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EEQ34747.1 - 1.2e-06 28.5 6.3 1.9 9.3 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ34747.1 - 7.3e-05 22.6 7.1 0.71 10.2 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ34747.1 - 0.00011 21.6 12.4 1.8 8.4 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ34747.1 - 0.01 16.1 4.2 7.1 7.3 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF627 PF04781.7 EEQ34747.1 - 0.013 15.1 0.0 1.1 8.8 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF627) TPR_19 PF14559.1 EEQ34747.1 - 0.053 13.8 10.9 1.2 9.5 0.3 4.1 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ34747.1 - 2.5 8.7 8.9 14 6.4 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA PF00004.24 EEQ34748.1 - 1.1e-48 164.7 0.0 4.3e-43 146.6 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ34748.1 - 4e-07 30.8 0.0 0.0013 19.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ34748.1 - 2.5e-05 23.7 0.1 0.00046 19.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEQ34748.1 - 8.6e-05 21.6 0.0 0.00043 19.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EEQ34748.1 - 0.00021 21.4 0.0 0.0064 16.6 0.0 3.5 3 1 0 3 3 1 1 AAA domain Parvo_NS1 PF01057.12 EEQ34748.1 - 0.00043 19.2 0.0 0.00078 18.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 EEQ34748.1 - 0.00056 20.0 0.1 0.013 15.6 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.1 EEQ34748.1 - 0.001 19.1 3.3 0.028 14.4 0.0 4.1 3 1 1 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.12 EEQ34748.1 - 0.0013 18.2 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.11 EEQ34748.1 - 0.0019 17.4 0.0 0.083 12.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_2 PF07724.9 EEQ34748.1 - 0.0026 17.6 0.0 0.0066 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EEQ34748.1 - 0.0038 17.5 0.0 0.094 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEQ34748.1 - 0.0052 16.6 0.0 0.27 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EEQ34748.1 - 0.0053 15.5 0.0 0.0089 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EEQ34748.1 - 0.0055 16.4 0.0 0.027 14.2 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 EEQ34748.1 - 0.017 14.2 0.2 0.067 12.3 0.0 2.1 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.16 EEQ34748.1 - 0.017 14.2 0.1 0.041 13.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ34748.1 - 0.017 14.8 0.0 0.074 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEQ34748.1 - 0.033 14.1 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EEQ34748.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EEQ34748.1 - 0.11 12.1 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEQ34748.1 - 0.13 11.7 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PPV_E1_C PF00519.12 EEQ34748.1 - 0.25 9.9 0.0 0.38 9.2 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase zf-C2H2 PF00096.21 EEQ34749.1 - 0.002 18.3 17.2 0.0065 16.7 4.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ34749.1 - 0.3 11.5 18.4 0.046 14.0 2.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ34749.1 - 0.98 9.8 17.7 8.7 6.8 1.7 3.7 3 0 0 3 3 3 0 Zinc-finger double domain Dynamin_M PF01031.15 EEQ34750.1 - 5.3e-114 379.9 0.0 9.2e-114 379.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EEQ34750.1 - 8.3e-56 188.4 1.0 1.9e-55 187.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EEQ34750.1 - 6.6e-32 109.2 1.0 1.6e-31 107.9 0.7 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEQ34750.1 - 0.00032 20.6 0.3 0.0022 17.9 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ34750.1 - 0.014 15.9 0.0 0.04 14.4 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 EEQ34750.1 - 0.12 12.0 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle SH3_9 PF14604.1 EEQ34751.1 - 2.2e-32 110.3 2.9 3.9e-16 58.3 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EEQ34751.1 - 1.3e-29 101.2 4.3 1.1e-14 53.4 0.3 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EEQ34751.1 - 7.6e-17 60.5 0.1 3.6e-08 32.7 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EEQ34751.1 - 1.3e-10 41.2 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein APH PF01636.18 EEQ34752.1 - 8.5e-13 48.5 0.0 1.7e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ34752.1 - 0.0013 18.3 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Brix PF04427.13 EEQ34753.1 - 5.6e-27 94.6 0.0 7.6e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain PX PF00787.19 EEQ34755.1 - 7e-13 48.3 0.4 2.8e-12 46.4 0.1 2.0 2 1 0 2 2 2 1 PX domain SAS4 PF15460.1 EEQ34756.1 - 2.4e-33 114.0 5.0 2.4e-33 114.0 3.5 1.8 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 TUSC2 PF15000.1 EEQ34756.1 - 0.062 13.3 2.7 0.25 11.3 1.9 2.1 1 0 0 1 1 1 0 Tumour suppressor candidate 2 RXT2_N PF08595.6 EEQ34756.1 - 0.19 11.5 4.9 0.6 9.8 3.4 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.7 EEQ34756.1 - 0.25 10.5 18.0 0.54 9.4 12.5 1.5 1 0 0 1 1 1 0 SDA1 BTV_NS2 PF04514.7 EEQ34756.1 - 0.66 8.8 7.6 1.4 7.7 5.3 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC45 PF02724.9 EEQ34756.1 - 0.91 7.4 7.4 1.6 6.6 5.1 1.5 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EEQ34756.1 - 1.1 7.1 19.4 1.7 6.4 13.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF572 PF04502.8 EEQ34756.1 - 1.7 7.7 17.8 0.071 12.3 7.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) DGF-1_C PF11040.3 EEQ34758.1 - 0.3 11.0 2.3 0.38 10.6 1.6 1.1 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Borrelia_P83 PF05262.6 EEQ34758.1 - 0.36 9.0 3.1 0.4 8.8 2.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3807 PF12720.2 EEQ34759.1 - 6.1e-44 150.2 4.3 7.1e-44 149.9 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) HVSL PF09749.4 EEQ34761.1 - 2.1e-70 236.4 0.2 2.5e-70 236.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.6 EEQ34763.1 - 1.4e-06 28.7 0.0 3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein Methyltransf_28 PF02636.12 EEQ34764.1 - 1e-37 129.8 0.0 1.5e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pathogen_betaC1 PF09593.5 EEQ34764.1 - 0.076 12.7 0.4 8.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein PALP PF00291.20 EEQ34765.1 - 2.8e-54 184.4 0.4 3.7e-54 184.0 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scm3 PF10384.4 EEQ34766.1 - 2e-24 84.8 0.1 3.9e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 BTB PF00651.26 EEQ34767.1 - 0.0072 16.3 0.2 0.027 14.4 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain APH PF01636.18 EEQ34768.1 - 2.3e-09 37.3 0.0 3.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ34768.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ34768.1 - 0.079 11.5 0.0 0.094 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.17 EEQ34768.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APG6 PF04111.7 EEQ34769.1 - 3.6e-128 427.0 0.0 4.6e-128 426.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Vps23_core PF09454.5 EEQ34769.1 - 0.043 13.4 0.6 0.083 12.5 0.4 1.5 1 0 0 1 1 1 0 Vps23 core domain DUF972 PF06156.8 EEQ34769.1 - 0.046 14.0 1.3 0.12 12.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2968 PF11180.3 EEQ34769.1 - 0.23 10.8 7.7 0.51 9.6 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) YlqD PF11068.3 EEQ34769.1 - 1.2 9.1 9.1 1 9.3 3.4 2.7 3 0 0 3 3 3 0 YlqD protein Aminotran_5 PF00266.14 EEQ34770.1 - 9.5e-28 96.9 0.0 1.4e-27 96.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Peroxin-13_N PF04088.8 EEQ34771.1 - 7.2e-60 201.5 0.1 1.2e-59 200.7 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EEQ34771.1 - 1.3e-09 37.4 0.0 2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ34771.1 - 1.5e-08 33.9 0.0 2.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ34771.1 - 3.4e-07 29.7 0.1 5.4e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain GST_C PF00043.20 EEQ34772.1 - 1.5e-09 37.6 0.0 2.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ34772.1 - 0.00051 20.2 0.1 0.0014 18.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ34772.1 - 0.0024 17.7 0.0 0.0059 16.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEQ34772.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ERO1 PF04137.10 EEQ34773.1 - 1.5e-133 445.2 0.0 1.9e-133 444.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TPP_enzyme_N PF02776.13 EEQ34774.1 - 3.3e-45 153.6 0.1 6.4e-45 152.7 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEQ34774.1 - 1.5e-33 115.4 0.0 3.2e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEQ34774.1 - 2.6e-18 66.0 0.0 7.4e-18 64.5 0.0 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EEQ34774.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit B12-binding PF02310.14 EEQ34774.1 - 0.043 13.6 0.2 0.66 9.8 0.3 2.6 2 0 0 2 2 2 0 B12 binding domain TPR_1 PF00515.23 EEQ34775.1 - 8.5e-26 88.4 1.9 2.4e-09 36.3 0.0 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ34775.1 - 1.1e-25 89.0 5.6 3.1e-11 42.7 0.1 4.5 2 2 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 EEQ34775.1 - 2.6e-23 80.0 3.0 1.3e-07 30.9 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ34775.1 - 4.3e-18 64.1 2.7 3.5e-05 24.0 0.0 5.7 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ34775.1 - 5e-17 62.0 1.3 1.1e-05 25.9 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ34775.1 - 5.6e-16 57.3 1.9 0.00082 19.3 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ34775.1 - 1.9e-14 53.7 2.8 0.0004 20.6 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ34775.1 - 2.5e-14 52.9 3.7 1.2e-08 34.8 0.1 3.9 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ34775.1 - 1.1e-13 49.8 0.2 3.4e-05 23.3 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ34775.1 - 1.3e-10 40.2 2.9 0.00062 19.3 0.0 5.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EEQ34775.1 - 3.9e-10 39.6 0.1 0.0017 18.4 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ34775.1 - 1.3e-08 34.5 0.7 0.0054 16.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EEQ34775.1 - 1.8e-06 27.9 1.3 0.00027 20.9 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EEQ34775.1 - 4.7e-06 26.7 3.1 1.6 9.3 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ34775.1 - 0.00067 18.8 0.3 0.78 8.7 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 EEQ34775.1 - 0.0019 17.9 0.0 3 7.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ34775.1 - 0.0023 17.8 0.5 0.45 10.5 0.1 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF1641 PF07849.6 EEQ34775.1 - 0.038 13.6 0.1 0.089 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) MIT PF04212.13 EEQ34775.1 - 0.045 13.6 1.2 2.8 7.8 0.3 3.8 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.7 EEQ34775.1 - 0.055 13.0 0.1 3.6 7.1 0.0 2.6 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 NatB_MDM20 PF09797.4 EEQ34775.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit RRM_1 PF00076.17 EEQ34776.1 - 1.4e-33 114.3 1.1 2.2e-18 65.6 0.1 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ34776.1 - 1.2e-22 79.7 0.1 7e-14 51.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ34776.1 - 2.2e-16 59.4 0.0 5.8e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEQ34776.1 - 0.68 9.8 3.4 0.97 9.3 0.1 2.6 3 1 0 3 3 3 0 RNA binding motif Fungal_trans PF04082.13 EEQ34777.1 - 2.8e-17 62.4 0.2 5.4e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ34777.1 - 2.2e-06 27.4 12.0 5.1e-06 26.3 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 EEQ34777.1 - 0.032 13.8 0.2 0.074 12.6 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SnoaL PF07366.7 EEQ34779.1 - 0.026 14.0 0.0 0.2 11.2 0.0 2.4 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase SHS2_Rpb7-N PF03876.12 EEQ34780.1 - 4.5e-14 52.3 0.1 7.5e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EEQ34780.1 - 6.7e-11 42.1 0.0 1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EEQ34780.1 - 0.084 13.0 0.0 0.22 11.6 0.0 1.6 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 DUF962 PF06127.6 EEQ34781.1 - 3.4e-26 90.9 0.1 6.1e-26 90.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) TPT PF03151.11 EEQ34781.1 - 0.17 11.4 8.1 0.046 13.3 1.3 2.3 1 1 1 2 2 2 0 Triose-phosphate Transporter family ATP-synt_ab PF00006.20 EEQ34782.1 - 7.9e-72 241.2 0.0 1.1e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEQ34782.1 - 2.4e-25 89.2 0.7 6.5e-25 87.8 0.2 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEQ34782.1 - 2.1e-15 56.7 2.5 4.8e-15 55.5 1.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEQ34782.1 - 0.017 15.0 0.7 0.051 13.4 0.5 1.9 1 0 0 1 1 1 0 HAS barrel domain THF_DHG_CYH PF00763.18 EEQ34783.1 - 7.5e-18 64.6 0.0 1.1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EEQ34783.1 - 3.5e-12 45.7 0.1 5e-09 35.4 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SPC25 PF06703.6 EEQ34784.1 - 5.1e-43 146.4 0.1 5.8e-43 146.2 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF106 PF01956.11 EEQ34785.1 - 5.8e-55 185.3 0.7 7.1e-55 185.0 0.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Fasciclin PF02469.17 EEQ34786.1 - 0.035 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Fasciclin domain MMS19_C PF12460.3 EEQ34787.1 - 6.1e-125 417.2 25.6 7.1e-125 416.9 9.2 4.2 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EEQ34787.1 - 1.2e-51 175.5 0.6 7.4e-42 143.4 0.0 4.1 4 1 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 EEQ34787.1 - 6.6e-08 32.7 5.6 0.22 11.8 0.1 5.3 4 1 0 4 4 4 2 HEAT repeats Neurochondrin PF05536.6 EEQ34787.1 - 0.00013 20.4 0.9 0.0029 15.9 0.0 3.0 3 0 0 3 3 3 1 Neurochondrin HEAT PF02985.17 EEQ34787.1 - 0.002 18.0 5.9 17 5.7 0.1 6.1 6 0 0 6 6 6 0 HEAT repeat Ipi1_N PF12333.3 EEQ34787.1 - 0.016 15.1 0.4 13 5.8 0.0 4.4 3 1 1 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 EEQ34787.1 - 0.019 15.4 6.4 50 4.5 0.0 6.4 5 1 0 5 5 5 0 HEAT-like repeat M11L PF11099.3 EEQ34787.1 - 0.089 12.5 0.7 14 5.4 0.1 2.7 2 0 0 2 2 2 0 Apoptosis regulator M11L like MRP_L53 PF10780.4 EEQ34787.1 - 0.36 10.8 3.4 0.48 10.4 0.2 2.8 3 0 0 3 3 3 0 39S ribosomal protein L53/MRP-L53 ATG16 PF08614.6 EEQ34789.1 - 0.85 9.4 38.7 0.34 10.7 13.2 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF3632 PF12311.3 EEQ34790.1 - 2.4e-47 161.1 0.5 2.4e-47 161.1 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Ribosomal_S4Pg PF11993.3 EEQ34791.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) Kdo PF06293.9 EEQ34793.1 - 0.0005 19.1 0.0 0.00073 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEQ34793.1 - 0.021 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain GPI-anchored PF10342.4 EEQ34794.1 - 3.4e-19 69.0 0.5 3.4e-19 69.0 0.3 2.5 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mito_fiss_reg PF05308.6 EEQ34794.1 - 1.2 8.4 5.4 1.7 7.9 3.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Big_5 PF13205.1 EEQ34794.1 - 2 9.0 16.4 0.074 13.6 0.9 2.7 1 1 1 2 2 2 0 Bacterial Ig-like domain Methyltransf_31 PF13847.1 EEQ34796.1 - 1.2e-27 96.3 0.0 1.6e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ34796.1 - 2.8e-27 95.0 0.0 5.8e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ34796.1 - 1e-17 64.3 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ34796.1 - 2.5e-17 62.7 0.0 3.5e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EEQ34796.1 - 5e-16 58.9 0.0 1.2e-15 57.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ34796.1 - 9.2e-16 58.4 0.0 1.4e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ34796.1 - 2.4e-15 56.7 0.0 5e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ34796.1 - 1.3e-10 41.3 0.0 2.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ34796.1 - 1.4e-07 31.0 0.0 1.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EEQ34796.1 - 1.5e-06 27.8 0.0 2.6e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EEQ34796.1 - 4.4e-06 26.2 0.0 8.7e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 EEQ34796.1 - 6e-05 22.1 0.0 0.00013 21.1 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.11 EEQ34796.1 - 7e-05 21.3 0.0 9.1e-05 20.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 EEQ34796.1 - 0.00042 19.4 0.0 0.0006 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EEQ34796.1 - 0.00044 19.0 0.0 0.00065 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 EEQ34796.1 - 0.0023 17.3 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EEQ34796.1 - 0.0024 16.9 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 EEQ34796.1 - 0.0042 16.2 0.0 0.0055 15.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 EEQ34796.1 - 0.025 13.4 0.0 0.048 12.5 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_8 PF05148.10 EEQ34796.1 - 0.026 14.1 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase GCD14 PF08704.5 EEQ34796.1 - 0.036 13.5 0.1 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PALP PF00291.20 EEQ34797.1 - 1.8e-33 116.1 0.0 2.3e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_S9 PF00326.16 EEQ34798.1 - 6e-39 133.4 0.0 8.6e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ34798.1 - 4.4e-14 52.4 0.1 8.3e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EEQ34798.1 - 8.9e-10 38.2 0.0 4.6e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EEQ34798.1 - 2.1e-08 33.9 0.1 4.2e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EEQ34798.1 - 4.1e-08 33.3 1.9 1.7e-07 31.3 1.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EEQ34798.1 - 1.6e-06 28.0 0.0 6.5e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EEQ34798.1 - 2.2e-06 27.4 0.0 4.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EEQ34798.1 - 2.8e-05 22.7 0.0 0.00053 18.5 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EEQ34798.1 - 3.6e-05 23.3 0.0 0.059 12.8 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EEQ34798.1 - 0.0017 17.9 0.0 0.044 13.3 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EEQ34798.1 - 0.0025 17.2 0.0 0.0053 16.2 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.5 EEQ34798.1 - 0.026 14.4 0.0 0.07 13.0 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein FSH1 PF03959.8 EEQ34798.1 - 0.036 13.4 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AMP-binding PF00501.23 EEQ34799.1 - 4.5e-165 549.0 0.0 3.7e-85 285.8 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEQ34799.1 - 1e-95 320.0 0.0 9.1e-37 126.5 0.1 5.2 4 1 0 4 4 4 3 Condensation domain PP-binding PF00550.20 EEQ34799.1 - 5e-16 58.7 0.0 3.5e-09 36.8 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ34799.1 - 1.1e-11 45.4 0.0 4e-05 24.4 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Peptidase_S6 PF02395.11 EEQ34799.1 - 1.1 7.3 0.2 30 2.5 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin A1 protease Cys_Met_Meta_PP PF01053.15 EEQ34800.1 - 1.1e-117 392.6 0.0 2.1e-99 332.4 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEQ34800.1 - 7.2e-13 48.2 0.0 1.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ34800.1 - 2.9e-09 36.1 0.2 5.5e-09 35.2 0.1 1.4 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ34800.1 - 1.2e-08 34.4 0.1 2e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EEQ34800.1 - 1.7e-07 30.6 0.0 2.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EEQ34800.1 - 0.00055 18.7 0.0 0.0008 18.2 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EEQ34800.1 - 0.026 12.8 1.5 0.42 8.8 1.0 2.1 1 1 0 1 1 1 0 Methionine gamma-lyase PQ-loop PF04193.9 EEQ34801.1 - 5.6e-33 112.2 10.6 1.9e-17 62.5 2.1 2.7 2 0 0 2 2 2 2 PQ loop repeat PTR2 PF00854.16 EEQ34802.1 - 8.5e-28 97.1 12.7 1.3e-27 96.5 8.8 1.2 1 0 0 1 1 1 1 POT family ATP-grasp_4 PF13535.1 EEQ34803.1 - 2.2e-22 79.6 0.0 6.2e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEQ34803.1 - 3.8e-06 25.8 0.0 0.013 14.2 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEQ34803.1 - 0.0036 16.7 0.0 0.036 13.4 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EEQ34803.1 - 0.016 15.1 0.0 0.077 12.8 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain Fungal_trans PF04082.13 EEQ34804.1 - 2.2e-12 46.3 0.3 4.6e-12 45.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ank_2 PF12796.2 EEQ34807.1 - 4.8e-21 74.8 1.4 9.9e-21 73.8 0.9 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ34807.1 - 8.9e-21 72.5 7.6 2e-07 30.4 0.2 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EEQ34807.1 - 1.1e-18 67.2 4.0 1.8e-10 41.0 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ34807.1 - 9.4e-18 62.5 4.3 0.00011 22.1 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EEQ34807.1 - 3.8e-12 46.0 3.4 5.1e-07 29.7 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Abhydrolase_1 PF00561.15 EEQ34808.1 - 1.6e-27 96.5 0.1 2.2e-26 92.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ34808.1 - 1e-17 64.8 0.8 2.8e-17 63.3 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ34808.1 - 1.1e-05 25.2 0.0 3.6e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EEQ34808.1 - 0.0018 18.1 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein PGAP1 PF07819.8 EEQ34808.1 - 0.013 15.1 0.3 0.022 14.3 0.2 1.3 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 EEQ34808.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase MIF4G_like_2 PF09090.6 EEQ34809.1 - 0.2 10.8 2.7 0.25 10.5 0.1 2.3 3 1 0 3 3 3 0 MIF4G like CBF PF03914.12 EEQ34810.1 - 2.9e-46 156.9 0.2 5.5e-46 156.0 0.1 1.5 1 0 0 1 1 1 1 CBF/Mak21 family Fer4_14 PF13394.1 EEQ34810.1 - 0.0025 17.8 0.0 0.016 15.2 0.0 2.3 1 1 1 2 2 2 1 4Fe-4S single cluster domain PRO8NT PF08082.6 EEQ34810.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain Utp12 PF04003.7 EEQ34810.1 - 0.026 14.4 0.1 0.091 12.6 0.0 1.9 2 0 0 2 2 2 0 Dip2/Utp12 Family Fer4_12 PF13353.1 EEQ34810.1 - 0.046 13.8 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF2115 PF09888.4 EEQ34810.1 - 0.11 12.6 0.0 0.39 10.8 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Mt_ATP-synt_B PF05405.9 EEQ34811.1 - 8e-49 165.2 8.5 9.7e-49 164.9 5.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PBP_sp32 PF07222.7 EEQ34811.1 - 0.15 11.1 5.3 0.25 10.5 3.7 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pkinase PF00069.20 EEQ34812.1 - 3.6e-25 88.5 0.0 4.7e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34812.1 - 8.3e-11 41.4 0.0 2.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Sel1 PF08238.7 EEQ34813.1 - 1.1e-19 70.3 9.1 7.5e-08 32.7 1.0 3.5 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.1 EEQ34813.1 - 0.0053 17.1 1.6 0.25 11.8 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ34813.1 - 0.21 12.3 2.5 0.29 11.8 0.2 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ34813.1 - 0.26 11.2 2.3 0.75 9.7 0.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat VPS9 PF02204.13 EEQ34814.1 - 9.2e-27 93.1 0.0 1.7e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.20 EEQ34815.1 - 1.8e-05 24.3 0.1 4.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEQ34815.1 - 0.00099 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EEQ34815.1 - 0.05 13.3 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PAS_3 PF08447.6 EEQ34816.1 - 7.2e-10 38.8 0.0 1.5e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EEQ34816.1 - 1.1e-06 29.0 0.0 0.011 16.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 EEQ34816.1 - 1.2e-05 25.1 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EEQ34816.1 - 0.0021 17.7 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold DUF3419 PF11899.3 EEQ34817.1 - 2e-143 477.7 0.0 4e-143 476.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_26 PF13659.1 EEQ34817.1 - 1.1e-07 31.9 0.0 1.3e-06 28.3 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ34817.1 - 2.6e-06 27.0 0.0 5.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ34817.1 - 1.1e-05 25.9 0.0 4.4e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ34817.1 - 2.4e-05 24.7 0.0 9.4e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ34817.1 - 0.00053 19.1 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EEQ34817.1 - 0.0009 19.6 0.0 0.0041 17.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain DUF2516 PF10724.4 EEQ34817.1 - 0.15 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) Acetyltransf_10 PF13673.1 EEQ34818.1 - 6.4e-10 39.1 0.1 2.2e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ34818.1 - 9.8e-08 31.9 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ34818.1 - 6.9e-07 29.3 0.0 2.2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ34818.1 - 6.3e-05 22.8 0.0 0.00022 21.0 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain A_deaminase PF00962.17 EEQ34819.1 - 1.7e-45 155.3 0.0 4e-45 154.1 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase BTB PF00651.26 EEQ34820.1 - 5.4e-14 52.1 0.0 6.9e-13 48.5 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain ATP-synt_ab_C PF00306.22 EEQ34820.1 - 0.13 12.7 0.0 1.3 9.5 0.0 2.3 1 1 1 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain zf-Sec23_Sec24 PF04810.10 EEQ34820.1 - 0.2 11.2 2.7 0.48 10.0 1.9 1.7 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger Pkinase PF00069.20 EEQ34821.1 - 2.3e-07 30.2 0.0 1.1e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34821.1 - 0.0083 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3343 PF11823.3 EEQ34821.1 - 0.14 11.4 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) adh_short PF00106.20 EEQ34822.1 - 1.1e-21 77.5 0.4 1.7e-21 76.8 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ34822.1 - 1.5e-12 47.5 0.2 1.7e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ34822.1 - 6.3e-11 42.5 0.3 7.7e-11 42.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEQ34822.1 - 1.6e-06 27.7 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ34822.1 - 1.3e-05 24.1 0.4 2e-05 23.4 0.3 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ECH PF00378.15 EEQ34824.1 - 2.6e-72 242.8 0.1 3.3e-72 242.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EEQ34824.1 - 0.034 14.2 0.1 0.077 13.1 0.0 1.7 1 1 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 EEQ34824.1 - 0.08 12.7 0.3 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 Rer1 PF03248.8 EEQ34825.1 - 1.5e-80 268.9 4.1 1.7e-80 268.7 2.9 1.0 1 0 0 1 1 1 1 Rer1 family MFS_1 PF07690.11 EEQ34825.1 - 0.0033 16.1 4.2 0.0043 15.8 2.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1538 PF07556.6 EEQ34825.1 - 0.025 13.6 1.2 0.41 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) PolyA_pol PF01743.15 EEQ34826.1 - 2e-10 40.9 0.0 3.2e-09 37.0 0.0 2.3 1 1 0 1 1 1 1 Poly A polymerase head domain Catalase PF00199.14 EEQ34827.1 - 9.9e-170 564.3 0.1 1.4e-169 563.8 0.1 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEQ34827.1 - 2e-14 53.1 0.1 5.5e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Ureidogly_hydro PF04115.7 EEQ34828.1 - 1.6e-44 151.1 0.0 2e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase ORC4_C PF14629.1 EEQ34828.1 - 0.049 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus MutS_V PF00488.16 EEQ34829.1 - 3.4e-83 278.6 0.0 5.3e-83 278.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEQ34829.1 - 2.2e-40 138.6 5.6 3.4e-40 138.0 3.9 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEQ34829.1 - 3e-22 78.7 0.0 7.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EEQ34829.1 - 1.1e-07 31.9 0.0 6.5e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 EEQ34829.1 - 0.00015 22.1 0.5 0.45 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain MutS_IV PF05190.13 EEQ34829.1 - 0.0011 19.0 0.1 0.0038 17.3 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EEQ34829.1 - 0.016 14.6 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EEQ34829.1 - 0.028 14.5 0.1 0.32 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EEQ34829.1 - 0.041 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sec63 PF02889.11 EEQ34830.1 - 3.2e-186 617.9 0.8 9.6e-107 356.8 0.0 2.7 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EEQ34830.1 - 8e-52 175.1 0.5 1.1e-30 106.3 0.0 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EEQ34830.1 - 5.4e-15 55.6 0.0 4.8e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ34830.1 - 3.8e-10 39.4 0.0 1.8e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEQ34830.1 - 9.1e-06 25.8 0.3 0.002 18.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 EEQ34830.1 - 0.00037 19.7 0.0 0.081 12.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_10 PF12846.2 EEQ34830.1 - 0.0058 16.1 0.1 4 6.7 0.0 3.1 2 1 0 3 3 3 2 AAA-like domain AAA_19 PF13245.1 EEQ34830.1 - 0.01 15.6 0.0 0.44 10.3 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EEQ34830.1 - 0.013 14.9 0.0 0.06 12.8 0.0 2.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EEQ34830.1 - 0.016 14.1 0.0 1.1 8.0 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein Peptidase_S9 PF00326.16 EEQ34831.1 - 1e-18 67.3 0.0 3.6e-16 59.0 0.0 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ34831.1 - 0.018 14.7 0.0 6.7 6.4 0.0 2.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.7 EEQ34831.1 - 0.1 11.0 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Terminase_5 PF06056.7 EEQ34832.1 - 0.015 14.8 0.3 0.027 14.0 0.2 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_6 PF01418.12 EEQ34832.1 - 0.05 13.3 0.0 0.47 10.2 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family MRP-L28 PF09812.4 EEQ34832.1 - 0.054 13.3 1.8 0.074 12.8 1.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Orthopox_A5L PF06193.6 EEQ34832.1 - 0.11 12.4 0.1 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like RTC PF01137.16 EEQ34833.1 - 2.4e-33 114.8 0.1 3.3e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EEQ34833.1 - 2.5e-32 110.9 0.0 4.3e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain 3-HAO PF06052.7 EEQ34834.1 - 2.7e-55 185.9 0.0 3.2e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EEQ34834.1 - 5.5e-05 22.5 0.1 9.4e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EEQ34834.1 - 0.012 15.0 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Cupin DZR PF12773.2 EEQ34834.1 - 0.012 15.3 0.3 0.027 14.2 0.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon AraC_binding PF02311.14 EEQ34834.1 - 0.015 14.9 0.1 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF3279 PF11682.3 EEQ34834.1 - 0.16 11.5 1.9 7.5 6.1 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) RNA_POL_M_15KD PF02150.11 EEQ34834.1 - 0.2 11.4 2.2 11 5.7 0.2 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit CAP_GLY PF01302.20 EEQ34835.1 - 6.9e-17 60.9 0.2 1.5e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain Spc7 PF08317.6 EEQ34835.1 - 0.0095 14.6 18.9 0.16 10.5 2.5 3.1 2 1 1 3 3 3 3 Spc7 kinetochore protein DUF1664 PF07889.7 EEQ34835.1 - 0.33 10.7 12.6 4.2 7.1 1.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EEQ34835.1 - 0.38 9.1 14.6 0.23 9.9 6.0 2.0 1 1 1 2 2 2 0 AAA domain PVL_ORF50 PF07768.6 EEQ34835.1 - 0.4 10.6 4.0 0.12 12.3 0.3 1.9 1 1 0 2 2 2 0 PVL ORF-50-like family Reo_sigmaC PF04582.7 EEQ34835.1 - 0.42 9.7 4.0 3.6 6.6 0.3 2.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 EEQ34835.1 - 0.99 8.9 35.2 2.1 7.9 1.2 3.1 2 1 1 3 3 3 0 IncA protein DUF745 PF05335.8 EEQ34835.1 - 3 7.3 12.0 1.5 8.3 3.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF745) NPV_P10 PF05531.7 EEQ34835.1 - 6.1 7.1 13.4 38 4.6 0.1 4.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 EEQ34835.1 - 8.7 6.4 16.8 12 5.9 3.9 3.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.20 EEQ34836.1 - 3.6e-36 124.6 0.0 1.4e-21 76.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34836.1 - 5e-12 45.4 0.0 5.3e-09 35.5 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEQ34836.1 - 0.003 17.3 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ34836.1 - 0.0033 16.4 0.0 1.1 8.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like DUF3632 PF12311.3 EEQ34837.1 - 1.8e-29 102.8 0.0 2.3e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF3632 PF12311.3 EEQ34838.1 - 3.2e-22 79.2 0.0 4.4e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Pkinase_Tyr PF07714.12 EEQ34839.1 - 3.6e-14 52.4 0.0 5.9e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EEQ34839.1 - 4.2e-09 35.9 0.0 3.8e-08 32.7 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain APH PF01636.18 EEQ34839.1 - 0.021 14.5 0.1 0.044 13.5 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ34839.1 - 0.1 12.1 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase OPT PF03169.10 EEQ34840.1 - 8.5e-86 288.7 45.8 9.9e-86 288.5 31.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PWWP PF00855.12 EEQ34841.1 - 5.4e-16 58.5 0.0 5.4e-16 58.5 0.0 3.2 3 1 0 3 3 3 1 PWWP domain ComA PF02679.10 EEQ34842.1 - 1.3e-55 188.0 0.0 3.3e-54 183.4 0.0 2.0 1 1 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) SpoIIE PF07228.7 EEQ34843.1 - 4.3e-12 46.1 0.1 1.9e-10 40.7 0.0 2.1 1 1 1 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EEQ34843.1 - 4.4e-08 32.7 0.1 7.6e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EEQ34843.1 - 2.6e-06 27.0 0.1 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C WD40 PF00400.27 EEQ34844.1 - 1.3e-47 157.9 20.9 2.4e-10 39.8 0.5 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EEQ34844.1 - 2.4e-14 52.2 1.0 4.3e-14 51.4 0.7 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EEQ34844.1 - 0.0068 15.5 0.0 0.32 10.0 0.0 2.5 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 EEQ34844.1 - 0.13 11.9 0.0 1.7 8.2 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A F-box-like PF12937.2 EEQ34845.1 - 0.00017 21.2 0.5 0.00017 21.2 0.4 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EEQ34845.1 - 0.0055 16.3 2.4 0.0059 16.2 0.6 1.8 2 0 0 2 2 2 1 F-box domain HSCB_C PF07743.8 EEQ34847.1 - 2.9e-19 69.2 0.3 1e-18 67.5 0.1 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EEQ34847.1 - 3.4e-11 42.7 0.0 2e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain SHD1 PF03983.7 EEQ34849.1 - 1.6e-34 117.3 0.1 3.1e-34 116.4 0.1 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EEQ34849.1 - 1e-31 108.0 6.7 2.3e-12 46.1 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EEQ34849.1 - 3.7e-29 100.0 7.7 2.6e-12 46.1 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EEQ34849.1 - 1.3e-21 75.7 0.3 5.9e-09 35.2 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.6 EEQ34849.1 - 0.0048 16.9 18.6 0.0048 16.9 12.9 5.0 2 2 2 4 4 4 1 Domain of unknown function (DUF1720) DUF2665 PF11654.3 EEQ34849.1 - 0.092 12.3 0.2 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) SH3_3 PF08239.6 EEQ34849.1 - 0.11 12.7 3.6 5.6 7.2 0.2 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain PRKCSH PF07915.8 EEQ34850.1 - 2.6e-18 66.5 0.1 2.6e-18 66.5 0.1 3.0 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein STT3 PF02516.9 EEQ34851.1 - 5.8e-133 444.3 39.9 1e-127 427.0 26.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit SNN_transmemb PF09049.5 EEQ34852.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Stannin transmembrane APH PF01636.18 EEQ34853.1 - 8.1e-18 65.0 0.0 1.4e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ34853.1 - 9.2e-05 21.5 0.0 0.1 11.6 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEQ34853.1 - 0.0025 17.4 0.0 0.0039 16.7 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ34853.1 - 0.013 14.8 0.0 0.96 8.7 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 EEQ34853.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EEQ34853.1 - 0.045 12.8 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pirin PF02678.11 EEQ34854.1 - 1.8e-32 111.3 0.1 3.3e-32 110.5 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EEQ34854.1 - 2.7e-25 88.4 0.0 8.9e-25 86.7 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EEQ34854.1 - 0.00012 21.5 1.8 0.0026 17.2 0.9 2.4 2 1 0 2 2 2 1 Cupin domain PMT PF02366.13 EEQ34855.1 - 4.2e-82 275.1 15.7 7.1e-82 274.4 10.9 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEQ34855.1 - 2.1e-20 73.0 0.9 7.4e-20 71.2 0.2 1.9 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 EEQ34855.1 - 0.0029 17.5 8.4 0.0029 17.5 5.8 3.1 4 1 1 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.27 EEQ34857.1 - 9.9e-18 63.2 5.4 7.5e-05 22.4 0.1 5.9 7 1 0 7 7 7 4 WD domain, G-beta repeat ATP-synt_E PF05680.7 EEQ34858.1 - 1.2e-22 79.6 0.4 1.2e-22 79.6 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain PCI_Csn8 PF10075.4 EEQ34859.1 - 4.4e-22 78.4 0.0 7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EEQ34859.1 - 3e-05 23.6 0.0 3.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 EEQ34859.1 - 0.069 13.4 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 PCI domain DUF3453 PF11935.3 EEQ34860.1 - 1.5e-67 227.5 3.3 3.7e-67 226.2 2.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3453) Coiled-coil_56 PF09813.4 EEQ34861.1 - 0.00068 19.5 0.0 0.00069 19.5 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Sds3 PF08598.6 EEQ34862.1 - 9.2e-15 54.7 0.6 5.3e-14 52.2 0.4 3.4 3 1 0 3 3 3 2 Sds3-like Daxx PF03344.10 EEQ34863.1 - 4.7e-05 22.0 26.9 5.6e-05 21.8 18.6 1.1 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 EEQ34863.1 - 0.00016 21.1 25.9 0.0002 20.7 18.0 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.5 EEQ34863.1 - 0.036 13.1 29.8 0.047 12.7 20.6 1.2 1 0 0 1 1 1 0 BUD22 MIP-T3 PF10243.4 EEQ34863.1 - 0.68 8.3 32.7 0.8 8.1 22.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 EEQ34863.1 - 4.9 6.1 20.2 6.3 5.8 14.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein GPI-anchored PF10342.4 EEQ34864.1 - 8.3e-07 29.3 0.1 8.3e-07 29.3 0.1 2.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DDHD PF02862.12 EEQ34864.1 - 0.17 11.6 3.8 0.23 11.2 2.6 1.1 1 0 0 1 1 1 0 DDHD domain NUFIP1 PF10453.4 EEQ34865.1 - 4.1e-09 35.8 17.9 4.1e-09 35.8 12.4 3.3 2 2 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EEQ34865.1 - 1.4e-07 31.0 4.7 2.2e-07 30.3 3.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF342 PF03961.8 EEQ34865.1 - 9.3 4.5 11.0 13 4.0 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RNA_pol_Rbc25 PF08292.7 EEQ34866.1 - 2.7e-35 121.2 0.1 3.7e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EEQ34866.1 - 1.2e-11 44.5 0.2 3.5e-11 43.0 0.1 1.8 1 1 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 APH PF01636.18 EEQ34867.1 - 8.6e-19 68.2 0.2 5.3e-10 39.4 0.0 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ34867.1 - 1.6e-10 40.8 0.2 1e-08 35.0 0.2 2.2 1 1 1 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EEQ34867.1 - 2.2e-06 26.8 0.0 3.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase Pkinase PF00069.20 EEQ34867.1 - 7.9e-05 21.9 0.0 0.0016 17.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.17 EEQ34867.1 - 0.0028 17.0 0.2 0.43 9.8 0.0 2.4 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.6 EEQ34867.1 - 0.011 14.3 0.0 0.23 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase_Tyr PF07714.12 EEQ34867.1 - 0.035 13.1 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase WaaY PF06176.6 EEQ34867.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Cys_Met_Meta_PP PF01053.15 EEQ34868.1 - 8e-136 452.3 0.0 9.2e-136 452.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEQ34868.1 - 1.2e-07 31.0 0.1 1.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEQ34868.1 - 0.0016 17.6 0.1 0.0026 16.9 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEQ34868.1 - 0.0017 17.2 0.1 0.0031 16.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ34868.1 - 0.0069 15.4 0.6 0.022 13.8 0.4 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Crinivirus_P26 PF07416.6 EEQ34868.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Crinivirus P26 protein Peptidase_M36 PF02128.10 EEQ34869.1 - 2.4e-152 507.1 3.3 3.1e-152 506.8 2.3 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EEQ34869.1 - 9.1e-13 47.4 2.1 2e-12 46.3 1.4 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EEQ34869.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Peptidase_MA_2 PF13485.1 EEQ34869.1 - 0.043 13.8 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily Methyltransf_16 PF10294.4 EEQ34872.1 - 0.0022 17.4 0.0 0.035 13.5 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 EEQ34872.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_6 PF08030.7 EEQ34872.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Reo_sigmaC PF04582.7 EEQ34874.1 - 3.2e-06 26.5 11.0 0.00072 18.8 3.2 2.9 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Filament PF00038.16 EEQ34874.1 - 5.1e-05 22.9 48.9 5.1e-05 22.9 33.9 2.8 2 1 1 3 3 3 2 Intermediate filament protein VirB3 PF05101.8 EEQ34874.1 - 0.49 10.4 0.2 0.83 9.6 0.1 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Ribosomal_60s PF00428.14 EEQ34875.1 - 0.085 13.2 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-C2H2 PF00096.21 EEQ34876.1 - 0.072 13.4 16.7 0.15 12.4 0.3 4.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ34876.1 - 4.9 7.7 17.0 7.8 7.0 0.4 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_S8 PF00082.17 EEQ34877.1 - 2.2e-35 122.1 10.4 3.2e-35 121.6 7.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ34877.1 - 8.6e-12 45.4 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 zf-C2H2 PF00096.21 EEQ34879.1 - 5.2e-06 26.4 41.2 0.0059 16.8 1.9 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ34879.1 - 0.0033 17.6 41.7 0.044 14.1 1.0 7.1 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ34879.1 - 0.13 12.4 13.7 0.24 11.6 0.3 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EEQ34879.1 - 2.1 8.7 21.4 0.38 11.0 0.8 5.2 5 0 0 5 5 5 0 C2H2-type zinc-finger domain Carb_kinase PF01256.12 EEQ34880.1 - 1.2e-50 172.0 0.3 3.2e-49 167.4 0.0 2.0 2 0 0 2 2 2 2 Carbohydrate kinase SPT2 PF08243.6 EEQ34881.1 - 2.5e-08 34.2 12.3 2.5e-08 34.2 8.5 2.0 2 0 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.14 EEQ34882.1 - 3.1e-27 94.8 10.8 3.6e-27 94.5 7.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4611 PF15387.1 EEQ34882.1 - 0.18 11.9 4.6 6.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Ribosomal_S19 PF00203.16 EEQ34883.1 - 8.3e-34 115.0 0.3 1.2e-33 114.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 EEQ34883.1 - 0.054 13.5 0.2 0.66 10.0 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain SET PF00856.23 EEQ34884.1 - 1.4e-13 51.5 0.0 8.4e-13 48.9 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EEQ34884.1 - 2.9e-09 36.6 5.8 2.9e-09 36.6 4.0 2.2 2 0 0 2 2 2 1 MYND finger CPSase_L_D2 PF02786.12 EEQ34886.1 - 1.2e-107 358.0 0.0 1.9e-83 278.9 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EEQ34886.1 - 1.4e-41 141.1 0.0 3.1e-41 139.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EEQ34886.1 - 3.9e-37 127.7 0.0 1.3e-21 77.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EEQ34886.1 - 1.8e-36 124.5 0.0 9.5e-17 61.0 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EEQ34886.1 - 1.3e-24 86.5 0.0 2.5e-08 33.0 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EEQ34886.1 - 2.2e-17 62.9 0.0 9.1e-08 31.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEQ34886.1 - 1.1e-14 54.3 0.0 1.1e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EEQ34886.1 - 8.4e-07 28.6 0.0 0.0019 17.6 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 EEQ34886.1 - 0.00023 20.4 0.0 0.072 12.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 EEQ34886.1 - 0.0053 16.6 0.0 0.032 14.1 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain GARS_A PF01071.14 EEQ34886.1 - 0.0082 15.7 0.0 0.48 9.9 0.0 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HNH_2 PF13391.1 EEQ34887.1 - 7.4e-16 57.6 0.0 1.6e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HC2 PF07382.6 EEQ34888.1 - 0.0095 15.8 1.6 0.016 15.1 1.1 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF4187 PF13821.1 EEQ34889.1 - 3.7e-19 68.0 3.0 1.2e-18 66.3 2.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EEQ34889.1 - 4e-08 32.8 4.0 3.2e-07 30.0 2.8 2.3 1 1 0 1 1 1 1 G-patch domain PALP PF00291.20 EEQ34890.1 - 2.1e-27 96.1 0.1 2.6e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 EEQ34890.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 LytB protein DUF212 PF02681.9 EEQ34890.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Divergent PAP2 family CDP-OH_P_transf PF01066.16 EEQ34891.1 - 6.5e-17 61.6 4.5 6.5e-17 61.6 3.1 2.9 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Peptidase_M1 PF01433.15 EEQ34892.1 - 1.9e-07 30.5 0.0 0.071 12.1 0.0 3.9 4 0 0 4 4 4 3 Peptidase family M1 HTH_psq PF05225.11 EEQ34892.1 - 0.055 13.0 0.1 1.3 8.5 0.0 2.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain LSM PF01423.17 EEQ34893.1 - 1.8e-15 56.2 0.5 1.4e-08 34.1 0.1 2.1 2 0 0 2 2 2 2 LSM domain NTR2 PF15458.1 EEQ34894.1 - 3.9e-77 258.9 19.3 5.9e-77 258.3 13.4 1.3 1 0 0 1 1 1 1 Nineteen complex-related protein 2 LtrA PF06772.6 EEQ34894.1 - 4.2e-12 45.6 27.5 3.1e-08 32.9 1.1 3.1 2 1 0 3 3 3 2 Bacterial low temperature requirement A protein (LtrA) Spc7 PF08317.6 EEQ34894.1 - 0.28 9.8 6.1 0.026 13.2 0.8 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Spc24 PF08286.6 EEQ34894.1 - 2.9 7.6 7.9 0.41 10.3 0.6 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 adh_short PF00106.20 EEQ34895.1 - 2.1e-18 66.8 0.0 2.8e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ34895.1 - 7.3e-07 29.1 0.0 9.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ34895.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEQ34895.1 - 0.0047 16.6 0.7 0.28 10.9 0.5 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EEQ34895.1 - 0.016 15.2 0.5 0.036 14.0 0.3 1.7 1 1 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EEQ34895.1 - 0.088 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ketoacyl-synt PF00109.21 EEQ34896.1 - 2.9e-71 239.9 0.0 8.6e-71 238.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ34896.1 - 9.8e-51 172.9 0.5 2.2e-50 171.8 0.4 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EEQ34896.1 - 1.2e-49 169.0 0.0 2.2e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EEQ34896.1 - 1.2e-48 165.2 0.2 3.1e-48 163.8 0.2 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EEQ34896.1 - 1.8e-36 125.6 1.9 2.1e-36 125.3 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEQ34896.1 - 1.1e-32 112.3 0.1 3.3e-32 110.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EEQ34896.1 - 8.5e-08 32.3 0.0 5.1e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 EEQ34896.1 - 2.8e-06 26.8 0.1 8.1e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EEQ34896.1 - 0.004 16.1 0.0 0.0082 15.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ectatomin PF06457.6 EEQ34896.1 - 0.33 10.6 0.1 0.68 9.6 0.1 1.5 1 0 0 1 1 1 0 Ectatomin FSH1 PF03959.8 EEQ34897.1 - 1.2e-23 83.6 0.0 5.3e-23 81.5 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EEQ34897.1 - 2.2e-05 24.4 0.2 2.6e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEQ34897.1 - 0.0035 16.8 0.8 0.083 12.3 0.1 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEQ34897.1 - 0.098 12.4 0.0 0.27 10.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.17 EEQ34899.1 - 6.4e-64 216.1 0.0 1.3e-63 215.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Chal_sti_synt_N PF00195.14 EEQ34900.1 - 4.9e-18 65.1 0.0 7.3e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 EEQ34900.1 - 1.6e-16 60.5 0.0 2.6e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.5 EEQ34900.1 - 1.6e-06 28.0 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EEQ34900.1 - 0.35 10.5 3.5 4.3 7.0 2.4 2.3 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cyt-b5 PF00173.23 EEQ34901.1 - 2.9e-08 33.3 0.1 1.2e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain RPN7 PF10602.4 EEQ34903.1 - 1.4e-50 171.1 0.1 2.5e-50 170.3 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EEQ34903.1 - 3.8e-11 43.2 0.1 2.5e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 PCI domain LEDGF PF11467.3 EEQ34903.1 - 0.059 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) zf-C2H2 PF00096.21 EEQ34904.1 - 0.0026 17.9 22.7 0.5 10.8 0.0 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EEQ34904.1 - 0.0054 16.6 0.6 0.33 10.9 0.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EEQ34904.1 - 0.0068 16.6 20.3 0.095 13.0 0.0 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger ATP_transf PF09830.4 EEQ34906.1 - 6.3e-22 77.1 0.0 1.1e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase MFS_1 PF07690.11 EEQ34908.1 - 5.7e-21 74.6 30.5 2.5e-10 39.6 4.7 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 EEQ34908.1 - 4.3e-12 45.2 3.3 3.4e-07 29.1 0.0 2.6 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EEQ34908.1 - 0.00035 20.2 0.2 0.6 9.9 0.0 3.0 3 0 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.1 EEQ34908.1 - 0.00091 17.7 17.3 0.0069 14.8 3.7 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.14 EEQ34908.1 - 0.87 8.0 14.2 0.017 13.7 1.0 3.2 4 0 0 4 4 4 0 LacY proton/sugar symporter BT1 PF03092.11 EEQ34908.1 - 1.2 7.7 6.4 0.61 8.7 0.1 2.9 3 0 0 3 3 3 0 BT1 family zf-rbx1 PF12678.2 EEQ34909.1 - 9.1e-12 44.9 0.7 1.6e-11 44.0 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEQ34909.1 - 2e-09 37.1 8.5 1.5e-08 34.3 5.9 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ34909.1 - 1e-07 31.5 4.2 9.5e-07 28.3 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ34909.1 - 3.2e-07 29.9 1.7 6.2e-07 28.9 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ34909.1 - 8.1e-06 25.7 1.9 8.1e-06 25.7 1.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ34909.1 - 0.00014 21.4 3.5 0.00087 18.9 2.6 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEQ34909.1 - 0.0036 17.1 4.9 0.029 14.1 3.4 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF329 PF03884.9 EEQ34909.1 - 0.011 15.2 0.6 0.035 13.6 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF329) TarH PF02203.10 EEQ34909.1 - 0.044 13.6 0.6 0.09 12.6 0.0 1.7 2 0 0 2 2 2 0 Tar ligand binding domain homologue Nucleoplasmin PF03066.10 EEQ34909.1 - 0.24 10.9 9.9 0.44 10.0 6.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin zf-RING_UBOX PF13445.1 EEQ34909.1 - 0.27 10.9 7.3 1 9.1 5.1 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEQ34909.1 - 0.37 10.6 1.5 0.8 9.6 1.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING NOA36 PF06524.7 EEQ34909.1 - 0.57 9.3 7.7 1.5 8.0 5.3 1.6 1 0 0 1 1 1 0 NOA36 protein zf-RING_4 PF14570.1 EEQ34909.1 - 1.2 8.7 4.3 0.41 10.2 0.9 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CDC27 PF09507.5 EEQ34909.1 - 1.7 7.8 16.2 3.3 6.8 11.2 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.8 EEQ34909.1 - 3 7.6 29.7 22 4.7 20.6 2.1 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SurE PF01975.12 EEQ34910.1 - 1.6e-36 125.4 0.2 2.2e-36 125.0 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE DUF3431 PF11913.3 EEQ34911.1 - 1.6e-86 289.4 0.0 2.4e-86 288.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DnaJ PF00226.26 EEQ34914.1 - 3.4e-20 71.5 1.3 3.4e-20 71.5 0.9 2.3 2 0 0 2 2 2 1 DnaJ domain DUF2043 PF09740.4 EEQ34914.1 - 0.87 9.7 9.5 0.18 11.9 0.8 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2043) RicinB_lectin_2 PF14200.1 EEQ34915.1 - 0.041 14.2 0.1 0.14 12.5 0.1 1.9 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.1 EEQ34918.1 - 0.15 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like NADH-u_ox-rdase PF10785.4 EEQ34919.1 - 0.11 12.7 0.2 0.28 11.4 0.0 1.8 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit APH PF01636.18 EEQ34920.1 - 1.4e-05 24.9 8.1 2.4e-05 24.2 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ34920.1 - 0.00018 20.7 0.0 0.0004 19.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EEQ34920.1 - 0.0024 16.9 0.0 0.0057 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.1 EEQ34920.1 - 0.045 13.5 0.1 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.15 EEQ34920.1 - 0.065 12.8 0.0 0.22 11.0 0.0 1.9 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mnd1 PF03962.10 EEQ34920.1 - 2.2 7.8 7.2 3.9 7.0 5.0 1.4 1 0 0 1 1 1 0 Mnd1 family tRNA-synt_1 PF00133.17 EEQ34922.1 - 4.2e-216 718.5 0.2 2.1e-215 716.3 0.2 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEQ34922.1 - 9.6e-35 119.5 1.1 9.6e-35 119.5 0.8 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEQ34922.1 - 5.3e-18 64.8 0.3 6.9e-08 31.5 0.0 4.8 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EEQ34922.1 - 8.1e-09 35.0 5.8 5.8e-06 25.7 0.0 3.2 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EEQ34922.1 - 0.0025 17.0 0.1 0.17 10.9 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Phage_B PF02304.10 EEQ34922.1 - 0.22 11.8 1.9 0.61 10.3 1.3 1.7 1 0 0 1 1 1 0 Scaffold protein B Pkinase PF00069.20 EEQ34923.1 - 3.9e-58 196.6 0.1 4.5e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34923.1 - 1e-19 70.6 0.0 1.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ34923.1 - 9.1e-09 35.3 0.1 0.00016 21.4 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ34923.1 - 0.012 15.2 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ34923.1 - 0.031 13.6 0.2 0.056 12.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 EEQ34923.1 - 0.058 12.3 0.1 0.12 11.3 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EEQ34923.1 - 0.061 12.3 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_P_p30 PF01876.11 EEQ34924.1 - 3.7e-50 169.0 0.2 4.8e-50 168.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit p30 F-box-like PF12937.2 EEQ34925.1 - 1.3e-05 24.8 0.0 2.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ34925.1 - 7.5e-05 22.2 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain A_deaminase PF00962.17 EEQ34927.1 - 2e-112 375.3 0.0 2.7e-112 374.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF676 PF05057.9 EEQ34927.1 - 0.049 12.9 0.7 1.6 8.0 0.0 2.4 1 1 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EEQ34929.1 - 2e-22 80.2 0.0 2.4e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ34929.1 - 2.2e-08 33.9 0.0 3.1e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ34929.1 - 0.0056 16.2 0.2 0.012 15.2 0.1 1.5 1 1 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.16 EEQ34929.1 - 0.035 13.3 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_8 PF06259.7 EEQ34929.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase PE-PPE PF08237.6 EEQ34929.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.15 EEQ34929.1 - 0.078 12.5 0.0 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold FGGY_C PF02782.11 EEQ34930.1 - 2e-71 239.6 0.4 4.4e-71 238.5 0.3 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEQ34930.1 - 9.8e-71 237.9 0.0 1.4e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 EEQ34931.1 - 3.8e-61 206.4 4.9 4.6e-61 206.1 3.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_S10 PF00450.17 EEQ34934.1 - 3.1e-90 303.3 0.0 4.1e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEQ34934.1 - 0.0027 17.6 0.0 0.0059 16.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3752 PF12572.3 EEQ34935.1 - 1.7e-43 148.3 14.1 1.7e-43 148.3 9.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Sigma70_ner PF04546.8 EEQ34935.1 - 0.095 12.3 12.1 0.52 9.8 0.7 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region PXA PF02194.10 EEQ34935.1 - 0.32 10.5 2.3 0.43 10.1 1.6 1.2 1 0 0 1 1 1 0 PXA domain FAM176 PF14851.1 EEQ34935.1 - 2.7 7.6 8.8 1.3 8.7 0.3 2.4 2 0 0 2 2 2 0 FAM176 family Atg14 PF10186.4 EEQ34935.1 - 4.1 6.2 7.9 5.7 5.7 5.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DSBA PF01323.15 EEQ34936.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain CASP_C PF08172.7 EEQ34936.1 - 0.067 12.2 0.2 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 CASP C terminal tRNA-synt_2c PF01411.14 EEQ34937.1 - 3.9e-216 718.6 0.0 3.9e-216 718.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EEQ34937.1 - 5.3e-18 64.6 0.6 1.5e-17 63.2 0.4 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EEQ34937.1 - 1e-08 34.7 0.9 3.3e-08 33.1 0.7 2.0 1 0 0 1 1 1 1 DHHA1 domain CCP_MauG PF03150.9 EEQ34937.1 - 0.1 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Pro_isomerase PF00160.16 EEQ34938.1 - 7.4e-50 169.1 0.7 8.4e-50 168.9 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lamp PF01299.12 EEQ34939.1 - 0.012 14.8 3.6 0.013 14.6 2.5 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) zf-RING_2 PF13639.1 EEQ34940.1 - 1.3e-13 50.4 6.8 2.2e-13 49.8 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ34940.1 - 2.5e-08 33.4 4.1 4.2e-08 32.7 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ34940.1 - 2e-07 30.9 4.4 4.3e-07 29.9 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEQ34940.1 - 1.3e-06 28.0 3.9 2.1e-06 27.3 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ34940.1 - 1.1e-05 25.3 5.7 1.8e-05 24.6 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ34940.1 - 3.1e-05 23.5 3.0 5.3e-05 22.7 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ34940.1 - 0.0023 17.7 3.4 0.0068 16.2 2.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EEQ34940.1 - 0.0084 15.8 0.3 0.023 14.4 0.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EEQ34940.1 - 0.023 14.2 6.0 0.04 13.4 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EEQ34940.1 - 0.066 13.1 4.9 0.15 11.9 3.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 EEQ34940.1 - 0.068 12.8 6.0 0.13 11.9 4.2 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EEQ34940.1 - 0.41 10.6 3.9 1.2 9.1 2.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EEQ34940.1 - 0.44 10.6 5.6 0.88 9.6 3.9 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EEQ34940.1 - 1.5 8.6 7.5 0.19 11.4 1.0 2.1 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3844 PF12955.2 EEQ34941.1 - 7.9e-37 125.4 4.2 1.3e-36 124.8 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Hce2 PF14856.1 EEQ34944.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor Glyco_transf_54 PF04666.8 EEQ34945.1 - 1.4e-17 63.4 0.0 8e-14 51.0 0.0 2.9 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Thioredoxin_4 PF13462.1 EEQ34947.1 - 3.6e-06 27.0 0.0 1.4e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin CKS PF01111.14 EEQ34948.1 - 7.2e-36 121.8 0.6 9.9e-36 121.4 0.4 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.20 EEQ34949.1 - 2.9e-18 65.5 5.3 7.6e-11 41.7 0.0 3.1 3 1 0 3 3 3 2 Bromodomain DUF1423 PF07227.6 EEQ34949.1 - 0.0039 15.9 0.2 0.0065 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1423) APH PF01636.18 EEQ34950.1 - 2.3e-15 56.9 0.0 4.5e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ34950.1 - 0.021 13.4 0.1 0.62 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EEQ34950.1 - 0.028 13.3 0.0 0.057 12.3 0.0 1.4 2 0 0 2 2 2 0 Fructosamine kinase DUP PF00674.13 EEQ34950.1 - 0.044 13.7 0.2 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 DUP family DUF3693 PF12472.3 EEQ34952.1 - 0.0055 16.2 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 Phage related protein HSP70 PF00012.15 EEQ34955.1 - 2.3e-233 775.5 9.3 2.6e-233 775.3 6.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ34955.1 - 2.5e-16 59.2 0.4 2e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EEQ34955.1 - 9.4e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EEQ34955.1 - 0.01 14.6 0.5 0.2 10.4 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain MRC1 PF09444.5 EEQ34955.1 - 0.17 12.1 3.6 0.12 12.6 0.8 1.9 2 0 0 2 2 2 0 MRC1-like domain RRF PF01765.14 EEQ34956.1 - 3.2e-25 88.5 1.9 5.5e-25 87.7 0.1 2.1 2 1 0 2 2 2 1 Ribosome recycling factor APC_CDC26 PF10471.4 EEQ34958.1 - 1.6e-20 73.5 2.2 1.8e-20 73.4 1.5 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Fungal_trans PF04082.13 EEQ34959.1 - 6e-10 38.4 0.1 6e-10 38.4 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ34959.1 - 2.7e-05 23.9 8.2 4.8e-05 23.1 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FimP PF09766.4 EEQ34959.1 - 0.42 9.6 15.8 0.7 8.8 10.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein Adeno_VII PF03228.9 EEQ34959.1 - 1.6 9.2 9.2 1.4 9.4 5.0 1.8 2 0 0 2 2 2 0 Adenoviral core protein VII PPP4R2 PF09184.6 EEQ34959.1 - 2.1 7.8 7.1 3.6 7.0 4.9 1.2 1 0 0 1 1 1 0 PPP4R2 Suf PF05843.9 EEQ34959.1 - 2.3 7.8 11.4 5.1 6.7 7.9 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF59 PF01883.14 EEQ34960.1 - 5.2e-08 32.7 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 Pheromone PF08015.6 EEQ34960.1 - 2.5 9.0 0.0 2.5 9.0 0.0 3.4 3 1 0 3 3 3 0 Fungal mating-type pheromone adh_short PF00106.20 EEQ34961.1 - 3e-24 85.8 4.5 7.4e-15 55.2 0.0 2.4 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ34961.1 - 2.9e-23 82.9 0.0 1.8e-22 80.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ34961.1 - 1.2e-05 25.0 0.7 0.003 17.2 0.2 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EEQ34961.1 - 0.0003 20.3 0.2 0.0033 16.8 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EEQ34961.1 - 0.00075 18.5 0.3 0.0011 18.0 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EEQ34961.1 - 0.0034 17.3 0.1 0.0064 16.4 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EEQ34961.1 - 0.0079 15.8 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EEQ34961.1 - 0.03 13.0 0.3 0.043 12.5 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EEQ34961.1 - 0.042 12.7 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EEQ34961.1 - 0.042 13.6 0.1 0.087 12.6 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EEQ34961.1 - 0.1 11.4 0.2 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF43 PF01861.11 EEQ34961.1 - 0.13 11.2 0.3 0.22 10.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 Chromate_transp PF02417.10 EEQ34962.1 - 3.5e-38 130.8 32.0 1.3e-28 99.7 10.4 3.5 3 1 1 4 4 4 3 Chromate transporter GTP_EFTU PF00009.22 EEQ34963.1 - 5.5e-45 153.1 0.0 8.7e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEQ34963.1 - 1.4e-23 82.7 0.0 4.6e-23 81.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EEQ34963.1 - 8e-19 67.3 0.0 2.9e-18 65.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEQ34963.1 - 6.6e-10 38.9 0.1 1.9e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EEQ34963.1 - 4.3e-07 29.6 0.1 1.2e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EEQ34963.1 - 1.2e-05 25.2 0.1 2.5e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ34963.1 - 0.00019 21.9 0.1 0.00055 20.4 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EEQ34963.1 - 0.023 14.0 0.0 0.065 12.6 0.0 1.9 1 0 0 1 1 1 0 Ras family SRPRB PF09439.5 EEQ34963.1 - 0.12 11.5 0.1 0.93 8.6 0.1 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EEQ34963.1 - 0.13 10.8 0.1 0.23 10.1 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit LysM PF01476.15 EEQ34964.1 - 2.2e-21 75.4 1.5 8.2e-05 22.4 0.0 4.8 4 1 1 5 5 5 4 LysM domain UPF0203 PF05254.7 EEQ34964.1 - 0.0021 17.8 6.3 0.57 10.0 0.0 4.1 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0203) Rab15_effector PF15208.1 EEQ34964.1 - 0.083 12.3 0.0 3.9 6.8 0.0 2.5 3 0 0 3 3 3 0 Rab15 effector Cyt-b5 PF00173.23 EEQ34965.1 - 2e-12 46.7 0.0 5e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EEQ34965.1 - 1.1e-11 44.6 19.8 1.1e-11 44.6 13.7 2.1 1 1 1 2 2 2 1 Fatty acid desaturase HsbA PF12296.3 EEQ34966.1 - 1.7e-22 79.5 0.0 2.3e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF1627 PF07789.7 EEQ34966.1 - 0.065 12.7 0.1 0.15 11.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1627) ketoacyl-synt PF00109.21 EEQ34967.1 - 3.9e-64 216.5 0.0 8e-64 215.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ34967.1 - 2.4e-63 214.3 0.0 5.2e-63 213.2 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EEQ34967.1 - 1.8e-59 200.4 1.2 2.7e-57 193.3 0.2 2.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 EEQ34967.1 - 3e-55 186.8 0.0 5.7e-55 185.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PS-DH PF14765.1 EEQ34967.1 - 9.6e-55 185.8 0.0 1.4e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EEQ34967.1 - 1.3e-44 152.0 2.4 2.3e-42 144.7 0.3 3.1 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEQ34967.1 - 2.2e-29 101.7 0.1 7.7e-29 99.9 0.1 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EEQ34967.1 - 8.3e-19 67.9 0.0 2.9e-18 66.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EEQ34967.1 - 8.4e-19 67.4 0.0 2.3e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ34967.1 - 1.7e-13 51.5 0.0 1e-12 49.0 0.0 2.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EEQ34967.1 - 1.5e-12 47.3 0.0 4.6e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ34967.1 - 6.7e-12 45.4 0.0 2.2e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EEQ34967.1 - 2.8e-10 40.0 0.0 7.9e-08 32.0 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EEQ34967.1 - 3.5e-10 40.4 0.0 1.5e-09 38.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ34967.1 - 5.8e-09 36.3 0.0 1.6e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EEQ34967.1 - 1.1e-08 34.1 0.0 0.00011 21.0 0.0 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_N PF08240.7 EEQ34967.1 - 1.5e-06 27.9 0.2 7e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 EEQ34967.1 - 0.00013 22.2 0.0 0.00056 20.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ34967.1 - 0.00027 20.1 0.0 0.00057 19.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EEQ34967.1 - 0.0021 18.2 0.0 0.0066 16.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 EEQ34967.1 - 0.033 14.2 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ34967.1 - 0.042 13.3 0.0 0.41 10.0 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase Thiolase_N PF00108.18 EEQ34967.1 - 0.042 12.8 0.2 0.08 11.9 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 EEQ34967.1 - 0.086 11.7 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EEQ34967.1 - 0.15 12.3 0.0 0.55 10.5 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Thiolase_N PF00108.18 EEQ34968.1 - 5.9e-98 327.0 0.1 8e-98 326.6 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEQ34968.1 - 6.3e-44 148.3 2.0 8.8e-44 147.8 0.8 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEQ34968.1 - 2.8e-05 23.7 1.1 2.8e-05 23.7 0.7 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EEQ34968.1 - 0.075 12.7 1.6 2.5 7.8 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.17 EEQ34969.1 - 3.3e-49 167.6 1.4 5.9e-49 166.7 1.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2401 PF10287.4 EEQ34970.1 - 2.9e-78 262.5 0.0 4e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EEQ34970.1 - 9.3e-19 67.3 0.5 2.1e-18 66.2 0.0 1.8 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) DUF4519 PF15012.1 EEQ34971.1 - 1.1 9.2 3.8 1.9 8.4 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Atg14 PF10186.4 EEQ34973.1 - 2.1e-89 299.4 0.0 2.7e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 THOC7 PF05615.8 EEQ34973.1 - 0.082 13.1 1.1 0.15 12.3 0.8 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Mito_fiss_reg PF05308.6 EEQ34974.1 - 0.093 12.0 3.4 0.043 13.1 0.5 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator LMBR1 PF04791.11 EEQ34975.1 - 3.6e-12 45.6 15.2 1.8e-10 40.0 10.5 2.3 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF1056 PF06341.6 EEQ34975.1 - 0.15 12.0 0.1 0.15 12.0 0.1 4.8 7 0 0 7 7 7 0 Protein of unknown function (DUF1056) DUF4470 PF14737.1 EEQ34977.1 - 1.3e-23 82.5 0.1 3.3e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EEQ34977.1 - 1.6e-11 43.9 10.5 3.4e-11 42.8 7.2 1.6 1 0 0 1 1 1 1 MYND finger PIG-F PF06699.6 EEQ34980.1 - 1.7e-53 181.4 8.4 2e-53 181.1 5.8 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2453 PF10507.4 EEQ34980.1 - 0.024 14.4 0.2 5.2 6.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2453) DUF4310 PF14187.1 EEQ34980.1 - 1.2 8.5 5.3 7 6.0 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4310) Amidase PF01425.16 EEQ34981.1 - 6.5e-87 292.1 0.0 8e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Lipoprotein_7 PF01540.11 EEQ34983.1 - 0.026 13.6 0.1 0.038 13.0 0.1 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein ADH_N PF08240.7 EEQ34985.1 - 9.3e-29 99.3 0.7 1.9e-28 98.3 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ34985.1 - 1.6e-17 63.2 0.1 3.4e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EEQ34985.1 - 0.063 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-Tim10_DDP PF02953.10 EEQ34986.1 - 6e-17 60.6 3.9 8e-17 60.3 2.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SLBP_RNA_bind PF15247.1 EEQ34986.1 - 0.072 12.8 0.0 0.34 10.7 0.0 1.9 1 1 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain Vicilin_N PF04702.7 EEQ34986.1 - 0.092 12.3 1.3 0.11 12.1 0.9 1.1 1 0 0 1 1 1 0 Vicilin N terminal region Connexin PF00029.14 EEQ34986.1 - 0.11 12.5 0.5 0.15 12.1 0.3 1.3 1 1 0 1 1 1 0 Connexin DUF234 PF03008.9 EEQ34986.1 - 0.12 12.5 0.1 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function Pkinase PF00069.20 EEQ34987.1 - 6.7e-28 97.5 0.0 8.6e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ34987.1 - 9.9e-12 44.4 0.0 7.2e-11 41.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase GRA6 PF05084.8 EEQ34988.1 - 0.00033 20.2 0.0 0.00035 20.1 0.0 1.0 1 0 0 1 1 1 1 Granule antigen protein (GRA6) RhoGAP PF00620.22 EEQ34992.1 - 7.9e-39 132.6 0.0 1.3e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Amidase PF01425.16 EEQ34993.1 - 7.6e-75 252.4 3.4 1.8e-72 244.6 1.5 2.9 1 1 1 2 2 2 2 Amidase RNA_GG_bind PF10258.4 EEQ34993.1 - 0.096 12.3 0.1 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 PHAX RNA-binding domain NAD_binding_5 PF07994.7 EEQ34995.1 - 1.6e-113 379.0 0.2 2e-113 378.8 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EEQ34995.1 - 2.1e-45 153.1 0.5 4.7e-45 152.0 0.3 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Ribonuclease_3 PF00636.21 EEQ34997.1 - 6.1e-09 36.3 0.0 1.8e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEQ34997.1 - 5.8e-06 26.2 0.0 7.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like SmpA_OmlA PF04355.8 EEQ34997.1 - 0.0072 15.9 0.1 4.4 6.9 0.0 2.5 2 1 0 2 2 2 2 SmpA / OmlA family Imm35 PF15581.1 EEQ34997.1 - 0.08 12.9 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 35 Peptidase_S10 PF00450.17 EEQ34998.1 - 7.8e-75 252.5 0.3 1.1e-74 252.0 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase LIM PF00412.17 EEQ35000.1 - 1.9e-18 66.2 17.8 9.3e-12 44.8 2.1 3.0 3 0 0 3 3 3 2 LIM domain zf-dskA_traR PF01258.12 EEQ35000.1 - 5.3 6.8 14.5 12 5.7 0.2 4.6 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger Glyco_hydro_3 PF00933.16 EEQ35001.1 - 2.7e-41 141.5 0.0 3.2e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain TctB PF07331.6 EEQ35002.1 - 1 9.0 12.1 0.76 9.4 4.6 2.5 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family COesterase PF00135.23 EEQ35003.1 - 8e-90 302.0 0.6 4.7e-79 266.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ35003.1 - 3.7e-10 39.7 0.0 6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ35003.1 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_2 PF00891.13 EEQ35004.1 - 6.3e-31 107.4 0.0 1.6e-30 106.1 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase DUF3754 PF12576.3 EEQ35005.1 - 1.5 8.4 4.6 0.54 9.8 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) DUF1049 PF06305.6 EEQ35005.1 - 2.6 7.5 8.9 4.3 6.8 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Pkinase PF00069.20 EEQ35006.1 - 6.3e-09 35.3 0.0 2e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35006.1 - 4.3e-07 29.2 0.0 9.7e-07 28.1 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EEQ35006.1 - 6.4e-06 26.0 0.4 1.4e-05 24.9 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ35006.1 - 0.00012 21.1 0.0 0.00028 19.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EEQ35006.1 - 0.085 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Asp_protease_2 PF13650.1 EEQ35008.1 - 0.063 13.7 0.0 0.094 13.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Phage_T4_gp19 PF06841.7 EEQ35008.1 - 0.071 12.7 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 T4-like virus tail tube protein gp19 AAA_11 PF13086.1 EEQ35010.1 - 3.8e-62 209.9 0.2 6.7e-62 209.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EEQ35010.1 - 9.2e-56 188.3 0.0 2.7e-55 186.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ35010.1 - 7e-14 51.3 2.6 9.1e-13 47.7 0.1 3.2 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 EEQ35010.1 - 2.1e-12 47.0 0.0 1.7e-10 40.8 0.0 2.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EEQ35010.1 - 1.4e-08 34.5 0.2 0.069 12.6 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EEQ35010.1 - 1.1e-06 28.5 0.0 2.4e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EEQ35010.1 - 1.5e-06 27.4 0.2 1.5e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EEQ35010.1 - 6.1e-06 25.7 0.1 0.00035 19.9 0.0 2.4 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EEQ35010.1 - 1.2e-05 25.4 0.1 0.00032 20.8 0.1 2.8 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.1 EEQ35010.1 - 2.6e-05 23.8 0.0 0.01 15.3 0.0 3.1 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EEQ35010.1 - 0.00019 21.4 0.5 0.00094 19.2 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 EEQ35010.1 - 0.00022 20.8 0.0 0.019 14.5 0.0 3.1 2 1 0 2 2 2 1 Helicase T2SE PF00437.15 EEQ35010.1 - 0.00051 19.0 0.0 0.0015 17.4 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 EEQ35010.1 - 0.002 17.6 0.0 0.0095 15.4 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 EEQ35010.1 - 0.0025 17.1 0.0 0.21 10.7 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein Flavi_DEAD PF07652.9 EEQ35010.1 - 0.0025 17.5 0.0 0.0078 15.9 0.0 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain TrwB_AAD_bind PF10412.4 EEQ35010.1 - 0.0058 15.3 0.0 0.011 14.3 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 EEQ35010.1 - 0.01 16.0 0.0 0.051 13.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 EEQ35010.1 - 0.012 15.7 0.0 6.2 7.0 0.0 2.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 EEQ35010.1 - 0.019 14.6 0.2 0.097 12.3 0.0 2.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Zot PF05707.7 EEQ35010.1 - 0.023 14.1 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 EEQ35010.1 - 0.026 13.4 0.0 1.3 7.8 0.0 2.5 2 0 0 2 2 2 0 PIF1-like helicase AAA_14 PF13173.1 EEQ35010.1 - 0.027 14.3 0.0 0.5 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEQ35010.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EEQ35010.1 - 0.06 12.7 0.0 0.18 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEQ35010.1 - 0.06 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EEQ35010.1 - 0.081 12.7 0.0 0.43 10.4 0.0 2.3 3 0 0 3 3 2 0 AAA domain CbiA PF01656.18 EEQ35010.1 - 0.083 12.2 0.2 0.35 10.2 0.1 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TK PF00265.13 EEQ35010.1 - 0.084 12.4 0.0 0.63 9.5 0.0 2.2 2 0 0 2 2 2 0 Thymidine kinase Herpes_ori_bp PF02399.10 EEQ35010.1 - 0.11 10.4 0.0 0.17 9.8 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein SRP54 PF00448.17 EEQ35010.1 - 0.11 11.9 0.0 5.9 6.2 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain HhH-GPD PF00730.20 EEQ35011.1 - 8.6e-20 71.0 0.0 2.9e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEQ35011.1 - 1.3e-05 24.6 0.0 4.9e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif UQ_con PF00179.21 EEQ35012.1 - 3.8e-39 133.3 0.0 4.5e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ35012.1 - 0.011 15.5 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.6 EEQ35012.1 - 0.011 15.1 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 EEQ35012.1 - 0.08 12.8 1.4 0.14 12.0 0.7 1.6 1 1 0 1 1 1 0 RWD domain Methyltransf_23 PF13489.1 EEQ35013.1 - 1.2e-21 77.1 0.0 2.3e-21 76.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ35013.1 - 5.8e-09 36.5 0.1 1e-07 32.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ35013.1 - 1.7e-07 30.9 0.0 2.8e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ35013.1 - 1.8e-07 31.5 0.0 1.2e-06 28.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ35013.1 - 2.2e-06 28.0 0.0 4.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ35013.1 - 0.00034 19.7 0.0 0.00075 18.6 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EEQ35013.1 - 0.00079 19.7 0.0 0.0028 17.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEQ35013.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EEQ35013.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 EEQ35013.1 - 0.066 12.2 0.0 0.15 11.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EEQ35013.1 - 0.073 12.5 0.0 2.4 7.6 0.0 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 EEQ35013.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 EEQ35013.1 - 0.13 11.3 0.0 0.41 9.7 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family p450 PF00067.17 EEQ35016.1 - 2.7e-50 171.2 0.0 2.8e-35 121.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HNH_2 PF13391.1 EEQ35017.1 - 5.1e-08 32.5 0.0 1.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease AMP-binding_C PF13193.1 EEQ35017.1 - 2.6e-07 31.4 0.0 8.1e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GSH-S_ATP PF02955.11 EEQ35017.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Cu_amine_oxid PF01179.15 EEQ35018.1 - 3.4e-161 536.6 2.6 2.7e-159 530.3 1.8 2.0 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EEQ35018.1 - 2.5e-06 27.4 0.0 5.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EEQ35018.1 - 0.00082 19.4 0.3 0.0016 18.4 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Tim17 PF02466.14 EEQ35019.1 - 1.9e-23 82.9 0.5 2.5e-23 82.5 0.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cpn60_TCP1 PF00118.19 EEQ35020.1 - 0.019 13.6 0.1 0.023 13.3 0.1 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family PALP PF00291.20 EEQ35021.1 - 8.6e-25 87.5 0.0 2.2e-24 86.2 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EEQ35021.1 - 5.6e-11 42.7 0.0 1.3e-09 38.4 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain NAF PF03822.9 EEQ35021.1 - 0.11 12.1 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 NAF domain MFS_1 PF07690.11 EEQ35022.1 - 3.3e-39 134.6 41.5 1.1e-36 126.2 28.1 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ35022.1 - 1.1e-16 60.1 22.4 1.5e-16 59.7 15.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ35022.1 - 1.5e-12 46.8 10.3 1.5e-12 46.8 7.1 3.9 3 1 1 4 4 4 3 Sugar (and other) transporter CPSF_A PF03178.10 EEQ35023.1 - 1.7e-94 316.5 0.0 2.2e-93 312.9 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EEQ35023.1 - 0.0018 16.4 0.0 0.019 13.1 0.0 2.2 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term SbcD_C PF12320.3 EEQ35024.1 - 0.089 12.8 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Abhydrolase_9 PF10081.4 EEQ35024.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family AAA PF00004.24 EEQ35025.1 - 1.6e-32 112.4 0.0 2.9e-27 95.4 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EEQ35025.1 - 9.6e-07 28.3 0.0 2.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EEQ35025.1 - 8.1e-06 25.8 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEQ35025.1 - 1.6e-05 24.9 0.1 0.00013 22.0 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain Bromodomain PF00439.20 EEQ35025.1 - 4.6e-05 23.2 0.0 0.00017 21.4 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AAA_19 PF13245.1 EEQ35025.1 - 0.00044 19.9 0.3 0.029 14.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EEQ35025.1 - 0.00092 19.3 0.1 0.014 15.5 0.1 2.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEQ35025.1 - 0.0022 18.1 0.0 0.01 15.9 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EEQ35025.1 - 0.0026 17.2 0.0 0.0083 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ35025.1 - 0.0028 17.3 0.0 0.007 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EEQ35025.1 - 0.0028 17.6 0.0 0.052 13.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.8 EEQ35025.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus ABC_tran PF00005.22 EEQ35025.1 - 0.017 15.4 0.0 0.061 13.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 EEQ35025.1 - 0.023 15.5 0.0 0.023 15.5 0.0 3.1 4 0 0 4 4 2 0 AAA domain AAA_33 PF13671.1 EEQ35025.1 - 0.024 14.5 0.0 0.024 14.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EEQ35025.1 - 0.028 13.5 0.0 0.069 12.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EEQ35025.1 - 0.038 13.8 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.7 EEQ35025.1 - 0.046 12.7 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 EEQ35025.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EEQ35025.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EEQ35025.1 - 0.068 12.8 0.1 0.24 11.0 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EEQ35025.1 - 0.074 12.5 0.0 2.4 7.5 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 EEQ35025.1 - 0.097 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EEQ35025.1 - 0.13 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EEQ35025.1 - 0.42 10.5 0.0 1.3 8.8 0.0 1.8 2 0 0 2 2 2 0 Torsin Sec66 PF09802.4 EEQ35026.1 - 6.3e-74 247.4 0.4 7.5e-74 247.2 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF1539 PF07560.6 EEQ35026.1 - 0.0075 16.1 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1539) Duffy_binding PF05424.6 EEQ35026.1 - 0.13 12.0 2.4 0.34 10.7 1.7 1.8 1 1 0 1 1 1 0 Duffy binding domain ORC3_N PF07034.6 EEQ35027.1 - 1.2e-35 123.0 0.0 6.8e-35 120.6 0.0 2.1 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus PPR_3 PF13812.1 EEQ35028.1 - 5.1e-11 41.9 1.2 0.055 13.7 0.0 7.9 8 1 1 9 9 9 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEQ35028.1 - 8.5e-09 35.2 0.1 0.13 12.2 0.0 5.8 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.15 EEQ35028.1 - 0.00093 19.0 2.2 1.1 9.4 0.0 4.7 5 0 0 5 5 5 2 PPR repeat HEAT_2 PF13646.1 EEQ35029.1 - 0.0029 17.8 0.1 0.0061 16.8 0.1 1.6 1 0 0 1 1 1 1 HEAT repeats Nop14 PF04147.7 EEQ35030.1 - 3e-277 921.9 16.3 3.5e-277 921.7 11.3 1.0 1 0 0 1 1 1 1 Nop14-like family COesterase PF00135.23 EEQ35031.1 - 4.1e-101 339.3 0.0 5.2e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ35031.1 - 3.3e-07 30.0 0.0 1.1e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ35031.1 - 1.5e-05 24.3 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEQ35031.1 - 0.00033 20.6 0.0 0.00054 19.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ35031.1 - 0.0026 17.5 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EEQ35031.1 - 0.025 13.4 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.2 EEQ35031.1 - 0.039 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme APH PF01636.18 EEQ35034.1 - 3.4e-14 53.1 0.0 4.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35034.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2935 PF11155.3 EEQ35034.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Peptidase_M6 PF05547.6 EEQ35035.1 - 1.2e-05 23.5 1.8 0.0011 17.0 0.5 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 RabGAP-TBC PF00566.13 EEQ35036.1 - 1e-40 139.5 0.0 2.4e-39 135.0 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Pkinase PF00069.20 EEQ35037.1 - 4.9e-22 78.3 0.0 8.2e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EEQ35037.1 - 1.5e-15 56.3 0.7 5.7e-08 32.3 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 EEQ35037.1 - 5e-10 38.6 6.4 0.028 14.4 0.1 6.5 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EEQ35037.1 - 1.4e-06 28.4 1.1 0.19 12.0 0.1 4.0 2 1 3 5 5 5 4 HEAT repeats Pkinase_Tyr PF07714.12 EEQ35037.1 - 1.1e-05 24.6 0.0 1.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2454 PF10521.4 EEQ35037.1 - 0.0029 16.6 0.4 0.009 15.0 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) HEAT_EZ PF13513.1 EEQ35037.1 - 0.23 12.0 3.7 0.75 10.3 0.2 3.5 4 0 0 4 4 4 0 HEAT-like repeat zf-C2H2_4 PF13894.1 EEQ35039.1 - 6.2e-10 38.6 15.5 0.0048 17.1 1.1 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ35039.1 - 1.6e-09 37.5 21.6 0.0012 19.0 2.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ35039.1 - 0.00016 21.8 17.6 0.47 10.8 0.3 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 EEQ35039.1 - 0.15 12.0 12.5 0.31 11.0 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ35039.1 - 0.15 12.2 6.7 0.48 10.6 1.9 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EEQ35039.1 - 0.44 10.5 7.5 2.1 8.3 0.8 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.2 EEQ35039.1 - 1.2 9.4 5.0 17 5.8 1.9 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EEQ35039.1 - 5.4 7.1 14.3 15 5.8 2.2 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) NUDIX PF00293.23 EEQ35040.1 - 1.6e-28 99.0 0.0 2.1e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF202 PF02656.10 EEQ35041.1 - 4.1e-19 68.5 1.5 4.1e-19 68.5 1.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF2499 PF10693.4 EEQ35041.1 - 0.031 14.3 0.4 0.074 13.0 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2499) COX4_pro_2 PF07835.7 EEQ35041.1 - 0.093 12.7 0.7 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV MatE PF01554.13 EEQ35042.1 - 7.4e-53 178.4 31.6 8.1e-29 100.3 7.7 2.3 2 0 0 2 2 2 2 MatE DnaJ PF00226.26 EEQ35043.1 - 1.8e-14 53.2 0.8 1.8e-14 53.2 0.6 2.4 3 0 0 3 3 3 1 DnaJ domain DEAD PF00270.24 EEQ35044.1 - 1.4e-44 151.6 0.1 2.7e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEQ35044.1 - 1.6e-25 88.4 0.1 3.7e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EEQ35044.1 - 1.2e-21 76.3 0.0 3.3e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EEQ35044.1 - 0.0006 19.8 0.2 0.0021 18.0 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 EEQ35044.1 - 0.0016 17.2 0.0 0.004 16.0 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain AA_permease PF00324.16 EEQ35045.1 - 1e-124 416.4 37.0 1.2e-124 416.3 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ35045.1 - 1.2e-38 132.7 43.1 1.6e-38 132.4 29.9 1.2 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 EEQ35045.1 - 0.75 9.9 14.4 0.048 13.7 1.2 4.1 4 0 0 4 4 4 0 PrgI family protein Zn_clus PF00172.13 EEQ35046.1 - 0.0002 21.1 10.5 0.00032 20.5 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EEQ35048.1 - 1.8e-32 112.1 0.1 6.2e-32 110.4 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ35048.1 - 1.2e-21 76.3 0.2 4.9e-21 74.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EEQ35048.1 - 5e-20 71.0 3.0 2.3e-19 68.9 2.1 2.3 1 0 0 1 1 1 1 DBP10CT (NUC160) domain RPA_C PF08784.6 EEQ35049.1 - 5e-13 49.3 0.0 1.3e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EEQ35049.1 - 4.8e-05 23.1 0.0 0.00034 20.3 0.0 2.1 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PAPS_reduct PF01507.14 EEQ35050.1 - 8.2e-28 97.3 0.0 8.4e-26 90.8 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.17 EEQ35051.1 - 5.6e-20 70.7 1.8 1.9e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ35051.1 - 4.6e-12 45.7 0.6 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ35051.1 - 2.4e-05 24.0 2.5 0.063 13.1 0.1 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ35051.1 - 0.049 13.4 0.1 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif FAD_binding_1 PF00667.15 EEQ35052.1 - 6.6e-64 215.3 0.0 9.7e-64 214.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EEQ35052.1 - 1.3e-34 119.2 0.7 2.4e-34 118.3 0.5 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EEQ35052.1 - 6e-21 75.0 0.0 5.5e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EEQ35052.1 - 0.0028 17.6 0.1 0.065 13.2 0.0 2.5 2 0 0 2 2 2 1 Flavodoxin domain MOR2-PAG1_N PF14222.1 EEQ35053.1 - 3.9e-226 752.0 0.0 7.1e-226 751.1 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EEQ35053.1 - 5e-74 249.3 0.9 2.8e-56 191.2 0.1 2.8 1 1 1 2 2 2 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EEQ35053.1 - 4.1e-41 140.6 9.5 1.5e-16 59.3 0.0 3.9 2 1 1 3 3 3 3 Cell morphogenesis central region Git3 PF11710.3 EEQ35054.1 - 1.3e-21 77.1 16.2 3.1e-21 75.8 11.3 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EEQ35054.1 - 3.8e-10 39.3 0.3 2.2e-09 36.9 0.2 2.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term DENN PF02141.16 EEQ35056.1 - 9.9e-38 129.7 0.1 1.7e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EEQ35056.1 - 0.00018 21.4 0.1 0.00064 19.6 0.0 2.1 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.6 EEQ35056.1 - 0.16 12.3 11.7 0.018 15.4 4.3 2.3 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DivIVA PF05103.8 EEQ35056.1 - 1.4 8.9 12.6 0.39 10.7 4.3 2.6 1 1 1 2 2 2 0 DivIVA protein Prog_receptor PF02161.10 EEQ35057.1 - 0.036 12.8 0.1 0.039 12.7 0.1 1.0 1 0 0 1 1 1 0 Progesterone receptor adh_short PF00106.20 EEQ35059.1 - 3.3e-29 101.9 0.2 4.6e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ35059.1 - 1.5e-23 83.7 0.3 1.8e-23 83.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ35059.1 - 7.5e-13 48.5 0.4 1.6e-12 47.4 0.3 1.5 1 1 0 1 1 1 1 KR domain Sulfotransfer_3 PF13469.1 EEQ35060.1 - 1.4e-05 26.0 0.1 2.8e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EEQ35060.1 - 0.017 14.3 0.0 0.24 10.6 0.0 2.5 1 1 0 1 1 1 0 Sulfotransferase domain DUF664 PF04978.7 EEQ35060.1 - 0.067 13.4 2.5 1.1 9.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF664) Sulfotransfer_3 PF13469.1 EEQ35061.1 - 0.015 16.1 1.7 0.051 14.5 1.1 1.7 1 1 0 1 1 1 0 Sulfotransferase family Spc7 PF08317.6 EEQ35062.1 - 0.059 12.0 2.8 0.1 11.2 1.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EEQ35062.1 - 0.091 11.9 4.5 0.44 9.6 3.2 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EEQ35062.1 - 0.26 10.1 6.3 0.88 8.4 4.4 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 EEQ35062.1 - 2.6 7.8 5.8 30 4.4 0.2 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF4611 PF15387.1 EEQ35064.1 - 0.53 10.4 6.0 0.41 10.8 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Peptidase_C48 PF02902.14 EEQ35065.1 - 3.3e-25 89.0 0.0 4.7e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PAP2 PF01569.16 EEQ35066.1 - 2.6e-16 59.4 2.8 6.9e-16 58.1 1.9 1.7 1 0 0 1 1 1 1 PAP2 superfamily Ras PF00071.17 EEQ35067.1 - 4.5e-47 159.4 0.0 5.6e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ35067.1 - 2.8e-11 43.9 0.0 4.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ35067.1 - 0.00015 21.0 0.0 0.00025 20.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ35067.1 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DASH_Dad1 PF08649.5 EEQ35068.1 - 3.1e-20 71.6 1.3 4e-20 71.2 0.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 SR-25 PF10500.4 EEQ35070.1 - 0.04 13.3 12.9 0.044 13.2 9.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FEZ PF07763.8 EEQ35070.1 - 0.044 13.4 0.6 0.051 13.2 0.4 1.1 1 0 0 1 1 1 0 FEZ-like protein BNIP3 PF06553.7 EEQ35070.1 - 0.06 12.7 3.5 0.068 12.5 2.4 1.1 1 0 0 1 1 1 0 BNIP3 DUF3774 PF12609.3 EEQ35070.1 - 0.34 11.8 4.4 0.41 11.5 3.1 1.2 1 0 0 1 1 1 0 Wound-induced protein TraG-D_C PF12696.2 EEQ35070.1 - 0.39 10.5 2.8 0.41 10.4 1.9 1.1 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG UPF0560 PF10577.4 EEQ35070.1 - 0.57 8.3 5.8 0.65 8.1 4.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 LSM PF01423.17 EEQ35071.1 - 7.5e-15 54.2 0.2 8.6e-15 54.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF866 PF05907.8 EEQ35072.1 - 1.1e-44 151.7 0.3 1.2e-44 151.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) FAD_binding_3 PF01494.14 EEQ35073.1 - 1.7e-69 234.5 0.0 2.1e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEQ35073.1 - 3.4e-38 130.9 0.0 5.5e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EEQ35073.1 - 0.0022 16.9 0.0 0.0052 15.7 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ35073.1 - 0.046 13.5 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ35073.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EEQ35073.1 - 0.15 10.5 0.0 0.31 9.4 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 EEQ35073.1 - 0.18 12.2 0.0 0.67 10.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase APH PF01636.18 EEQ35074.1 - 8.1e-15 55.1 0.0 2.2e-10 40.6 0.0 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35074.1 - 5.2e-10 39.2 0.0 1.4e-09 37.8 0.0 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EEQ35074.1 - 0.00087 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase EcKinase PF02958.15 EEQ35074.1 - 0.022 13.9 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 EEQ35074.1 - 0.14 11.2 0.0 5.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DDHD PF02862.12 EEQ35076.1 - 1e-43 149.7 0.0 2.1e-25 89.8 0.0 2.5 1 1 1 2 2 2 2 DDHD domain Abhydrolase_6 PF12697.2 EEQ35076.1 - 0.021 14.6 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family MoCF_biosynth PF00994.19 EEQ35077.1 - 8.9e-49 164.5 0.1 2e-25 88.8 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EEQ35077.1 - 3.4e-34 117.5 1.5 5.2e-34 116.9 1.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EEQ35077.1 - 1.4e-17 63.3 0.1 3.3e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) ATP-synt_C PF00137.16 EEQ35078.1 - 4.2e-25 87.4 32.4 3e-18 65.4 5.5 2.6 3 0 0 3 3 3 2 ATP synthase subunit C Ras PF00071.17 EEQ35079.1 - 6.8e-60 201.1 0.5 8.8e-60 200.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ35079.1 - 3.3e-20 72.7 0.1 5.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ35079.1 - 4.5e-18 65.1 0.4 5.5e-18 64.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ35079.1 - 2.1e-07 30.5 0.1 9.7e-07 28.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEQ35079.1 - 7.4e-06 25.2 0.2 9e-06 24.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ35079.1 - 9.1e-06 25.6 0.1 1.7e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEQ35079.1 - 1.2e-05 24.6 0.1 1.6e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EEQ35079.1 - 0.026 14.3 0.3 2.9 7.6 0.0 2.6 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 EEQ35079.1 - 0.028 14.3 0.4 0.083 12.8 0.3 1.8 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EEQ35079.1 - 0.054 13.1 0.1 0.23 11.1 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase Kei1 PF08552.6 EEQ35080.1 - 1.4e-22 80.3 0.7 5.6e-22 78.3 0.5 1.8 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NIR_SIR PF01077.17 EEQ35081.1 - 1.4e-52 177.1 0.1 4.6e-44 149.5 0.0 2.9 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EEQ35081.1 - 5.1e-29 99.7 0.0 3.9e-14 52.0 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EEQ35081.1 - 1.7e-27 96.1 0.0 3.7e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EEQ35081.1 - 2.5e-06 27.1 0.3 1e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Sin_N PF04801.8 EEQ35082.1 - 5e-28 98.1 2.0 1.7e-26 93.0 1.4 2.1 1 1 0 1 1 1 1 Sin-like protein conserved region RNA_pol PF00940.14 EEQ35083.1 - 4e-163 542.6 0.0 7.2e-163 541.7 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EEQ35083.1 - 1.4e-78 264.4 1.0 2.1e-78 263.7 0.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal T2SI PF02501.12 EEQ35085.1 - 0.013 15.3 1.9 0.023 14.6 1.3 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I Radical_SAM PF04055.16 EEQ35086.1 - 1.4e-11 44.8 0.0 2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EEQ35086.1 - 6.7e-07 29.5 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EEQ35086.1 - 0.00043 20.2 0.1 0.00091 19.2 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Pkinase PF00069.20 EEQ35087.1 - 1.7e-08 33.9 0.0 2.2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EEQ35087.1 - 4.6e-05 22.5 0.0 7.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ35087.1 - 0.00011 22.0 0.8 0.00035 20.3 0.6 1.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 EEQ35087.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) FGF-BP1 PF06473.7 EEQ35088.1 - 0.0018 17.9 3.2 0.0045 16.6 2.2 1.6 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) GAS PF13851.1 EEQ35088.1 - 0.0027 16.9 0.1 0.0027 16.9 0.1 1.6 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding SEO_N PF14576.1 EEQ35088.1 - 0.12 11.6 0.0 0.32 10.2 0.0 1.7 1 0 0 1 1 1 0 Sieve element occlusion N-terminus IncA PF04156.9 EEQ35088.1 - 0.23 11.0 3.7 0.62 9.6 0.0 2.6 3 0 0 3 3 3 0 IncA protein Pkinase PF00069.20 EEQ35089.1 - 4e-53 180.2 0.0 5.8e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35089.1 - 1.4e-30 106.2 0.0 2.2e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ35089.1 - 6.2e-05 22.1 0.0 9.4e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FHA PF00498.21 EEQ35089.1 - 0.0088 16.1 0.0 0.027 14.5 0.0 1.9 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 EEQ35089.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEQ35090.1 - 0.00025 20.2 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ35091.1 - 8.1e-16 58.4 0.0 2.9e-15 56.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35091.1 - 0.00034 20.2 0.1 0.00099 18.7 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EEQ35091.1 - 0.023 13.6 0.0 0.051 12.5 0.0 1.6 1 1 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.20 EEQ35091.1 - 0.15 11.2 0.0 0.51 9.4 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35096.1 - 3.8e-14 52.3 0.0 1.3e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EEQ35096.1 - 7.3e-13 48.2 0.0 5.4e-12 45.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EEQ35098.1 - 1.3e-15 57.2 0.0 4.5e-15 55.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35098.1 - 1.9e-06 27.1 0.0 1.8e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Profilin PF00235.14 EEQ35099.1 - 6.4e-14 52.1 0.0 1.4e-13 51.0 0.0 1.5 1 1 0 1 1 1 1 Profilin DUF2585 PF10755.4 EEQ35099.1 - 0.091 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) DUF92 PF01940.11 EEQ35100.1 - 8.9e-61 204.9 4.6 1.2e-60 204.5 3.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF192 PF02643.10 EEQ35100.1 - 0.15 11.7 0.0 0.41 10.3 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized ACR, COG1430 Pyr_redox_3 PF13738.1 EEQ35101.1 - 2.9e-16 60.1 0.0 7.9e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ35101.1 - 3.5e-08 32.7 0.0 0.00092 18.2 0.0 3.7 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EEQ35101.1 - 2.3e-07 29.4 0.0 3.6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EEQ35101.1 - 3.7e-06 26.8 0.0 1.4e-05 24.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ35101.1 - 0.00035 20.4 0.0 0.066 13.0 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ35101.1 - 0.031 13.1 0.0 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1469 PF07332.6 EEQ35102.1 - 0.00016 21.3 0.4 0.00016 21.3 0.3 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1469) Methyltransf_33 PF10017.4 EEQ35104.1 - 4.2e-29 101.0 0.0 7.5e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EEQ35104.1 - 3.5e-21 75.7 2.1 1.6e-20 73.6 1.4 1.9 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EEQ35104.1 - 1.5e-06 28.5 0.4 9.7e-06 25.9 0.2 2.3 2 0 0 2 2 2 1 DinB superfamily DUF1069 PF06370.6 EEQ35104.1 - 0.063 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Aldedh PF00171.17 EEQ35106.1 - 2.5e-132 441.5 0.0 2.7e-132 441.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EEQ35106.1 - 8.4e-07 28.0 0.1 1e-05 24.4 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) MFS_1 PF07690.11 EEQ35107.1 - 2.2e-32 112.1 41.6 2.2e-32 112.1 28.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ35107.1 - 1.2e-08 33.9 9.7 1.2e-08 33.9 6.7 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.13 EEQ35108.1 - 2.7e-10 39.5 0.1 4.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ35108.1 - 1.3e-06 28.1 6.5 2.7e-06 27.1 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EEQ35108.1 - 0.00096 19.3 5.9 0.00096 19.3 4.1 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ35108.1 - 0.043 14.1 5.3 0.043 14.1 3.7 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ35108.1 - 3.5 8.0 21.5 0.56 10.5 0.3 3.9 4 0 0 4 4 4 0 Zinc-finger double domain DUF1179 PF06678.6 EEQ35109.1 - 1.6 9.0 10.9 2.1 8.6 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1179) Lipase_GDSL_2 PF13472.1 EEQ35110.1 - 5.6e-10 39.6 0.3 2.1e-09 37.7 0.2 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ35110.1 - 7.5e-09 35.7 0.0 1.7e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CoA_binding_2 PF13380.1 EEQ35110.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Lipase_GDSL_3 PF14606.1 EEQ35110.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family TFIIA_gamma_N PF02268.11 EEQ35111.1 - 2.1e-26 91.2 0.2 3e-26 90.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EEQ35111.1 - 3.8e-26 90.6 3.2 5.4e-26 90.1 2.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Hexokinase_1 PF00349.16 EEQ35114.1 - 3.8e-26 91.7 0.0 7.2e-24 84.2 0.0 3.0 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EEQ35114.1 - 4.6e-26 91.5 0.0 2.4e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 Hexokinase GILT PF03227.11 EEQ35115.1 - 6.6e-10 38.8 0.6 2e-09 37.2 0.0 2.0 2 1 1 3 3 3 1 Gamma interferon inducible lysosomal thiol reductase (GILT) MFS_1 PF07690.11 EEQ35117.1 - 1.3e-21 76.7 30.0 1.1e-17 63.7 8.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Spc97_Spc98 PF04130.8 EEQ35118.1 - 1.9e-76 257.5 0.0 2.9e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family CBM_19 PF03427.8 EEQ35119.1 - 0.0058 16.3 1.3 0.0058 16.3 0.9 2.0 3 0 0 3 3 3 1 Carbohydrate binding domain (family 19) ThiF PF00899.16 EEQ35120.1 - 2.6e-54 182.7 0.0 3.8e-32 110.9 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EEQ35120.1 - 5.5e-40 134.7 4.4 2.3e-26 91.1 0.3 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EEQ35120.1 - 9.5e-38 129.1 0.0 1.8e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EEQ35120.1 - 5.9e-25 86.3 1.9 3.1e-21 74.4 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EEQ35120.1 - 0.0022 18.1 0.0 0.02 15.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Resolvase PF00239.16 EEQ35120.1 - 0.045 13.6 0.0 0.36 10.6 0.0 2.3 2 0 0 2 2 2 0 Resolvase, N terminal domain GST_N_2 PF13409.1 EEQ35122.1 - 4e-22 77.9 0.0 1e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ35122.1 - 2.3e-09 37.0 0.0 4.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ35122.1 - 7.1e-07 29.3 0.1 4.4e-05 23.6 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ35122.1 - 0.0011 18.8 0.0 0.0028 17.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ35122.1 - 0.0031 17.9 0.0 0.0081 16.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 EEQ35123.1 - 1.4e-46 156.1 7.8 3.3e-22 78.0 0.1 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EEQ35123.1 - 2.6e-22 78.7 3.9 7.3e-13 48.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEQ35123.1 - 1.1e-19 68.1 2.7 0.00016 20.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 EEQ35123.1 - 7.9e-15 53.4 3.2 0.0001 21.4 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EEQ35123.1 - 5.9e-14 50.6 6.0 0.00016 21.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EEQ35123.1 - 1.6e-13 50.0 1.9 1.2e-05 24.7 0.1 3.1 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EEQ35123.1 - 3.3e-10 39.9 0.3 9.5e-06 25.6 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EEQ35123.1 - 0.003 17.2 4.4 0.21 11.3 0.3 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EEQ35123.1 - 0.0048 16.5 0.1 4.7 6.9 0.0 2.5 2 0 0 2 2 2 2 EF hand Cyclin_N PF00134.18 EEQ35124.1 - 3.9e-12 45.8 0.1 6e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4452 PF14618.1 EEQ35125.1 - 1.6e-51 174.3 8.8 2.1e-51 173.9 6.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) FAM117 PF15388.1 EEQ35125.1 - 7.5 5.6 11.3 2.6 7.2 0.8 2.1 2 0 0 2 2 2 0 Protein Family FAM117 zf-RAG1 PF10426.4 EEQ35126.1 - 0.29 11.1 2.0 10 6.1 0.9 2.3 1 1 1 2 2 2 0 Recombination-activating protein 1 zinc-finger domain F-box-like PF12937.2 EEQ35127.1 - 2.4e-05 23.9 1.1 5.7e-05 22.7 0.8 1.7 1 0 0 1 1 1 1 F-box-like DUF3433 PF11915.3 EEQ35128.1 - 3.9e-42 142.3 18.7 4.8e-24 84.3 3.5 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Pkinase PF00069.20 EEQ35129.1 - 3.7e-11 42.6 0.0 3.5e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35129.1 - 3.8e-11 42.5 0.0 6.8e-11 41.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EEQ35129.1 - 0.00033 20.2 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EEQ35129.1 - 0.0066 16.1 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ35129.1 - 0.027 13.5 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Baculo_VP1054 PF05789.6 EEQ35129.1 - 0.038 13.1 0.1 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus VP1054 protein Cwf_Cwc_15 PF04889.7 EEQ35130.1 - 0.00044 20.0 23.5 0.0006 19.6 16.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Mitofilin PF09731.4 EEQ35130.1 - 0.21 10.2 17.5 0.27 9.8 12.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Astro_capsid PF03115.9 EEQ35130.1 - 0.37 8.9 9.1 0.44 8.7 6.3 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SPX PF03105.14 EEQ35130.1 - 0.39 10.4 17.2 0.5 10.0 11.9 1.1 1 0 0 1 1 1 0 SPX domain Exonuc_VII_L PF02601.10 EEQ35130.1 - 0.87 8.7 8.0 1 8.4 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF572 PF04502.8 EEQ35130.1 - 1.1 8.4 20.1 1.3 8.1 14.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF342 PF03961.8 EEQ35130.1 - 1.3 7.3 7.8 1.6 7.0 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pox_Ag35 PF03286.9 EEQ35130.1 - 1.7 8.1 13.9 2.6 7.5 9.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIA PF03153.8 EEQ35130.1 - 2.2 8.1 15.3 2.7 7.7 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APG6 PF04111.7 EEQ35130.1 - 2.9 6.8 14.3 4 6.4 9.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 EEQ35130.1 - 4.7 7.0 19.1 3.1 7.6 12.1 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EEQ35130.1 - 5.1 4.8 8.6 6 4.5 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 EEQ35130.1 - 6.1 6.7 19.2 18 5.2 12.7 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.5 EEQ35130.1 - 7.6 6.6 10.8 0.55 10.3 2.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TPD52 PF04201.10 EEQ35131.1 - 0.0015 18.2 0.0 0.01 15.5 0.0 2.2 2 1 1 3 3 3 1 Tumour protein D52 family CCDC155 PF14662.1 EEQ35131.1 - 0.042 13.4 2.5 0.055 13.0 1.1 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 bZIP_2 PF07716.10 EEQ35131.1 - 1.6 8.6 6.8 16 5.4 3.2 3.1 2 1 0 2 2 2 0 Basic region leucine zipper PTR2 PF00854.16 EEQ35133.1 - 1.6e-52 178.5 8.6 8.9e-30 103.7 1.8 2.3 1 1 1 2 2 2 2 POT family YqzM PF14141.1 EEQ35133.1 - 0.044 13.5 0.3 0.19 11.5 0.2 2.1 1 0 0 1 1 1 0 YqzM-like protein APH PF01636.18 EEQ35134.1 - 0.0021 17.8 0.0 0.032 13.9 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Chordopox_A15 PF05846.7 EEQ35134.1 - 0.037 14.0 0.3 0.088 12.8 0.1 1.8 2 0 0 2 2 2 0 Chordopoxvirus A15 protein APH PF01636.18 EEQ35135.1 - 5e-07 29.7 0.0 9.4e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family IDO PF01231.13 EEQ35135.1 - 0.12 10.7 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase PRCC PF10253.4 EEQ35137.1 - 0.55 10.9 3.8 0.59 10.7 2.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF601 PF04642.7 EEQ35137.1 - 0.76 9.0 3.5 0.73 9.1 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF601 EVI2A PF05399.6 EEQ35137.1 - 1.3 8.2 4.5 1.6 7.8 3.1 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) CAF-1_p150 PF11600.3 EEQ35137.1 - 4.3 6.6 9.3 5.7 6.2 6.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_12 PF13087.1 EEQ35140.1 - 1.3e-38 132.4 0.0 2.5e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ35140.1 - 2.2e-22 79.8 0.7 7.2e-22 78.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EEQ35140.1 - 4.1e-07 29.3 1.6 0.00053 19.0 0.0 2.6 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EEQ35140.1 - 5.9e-06 25.9 0.0 2e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ35140.1 - 4.3e-05 23.1 0.1 0.0027 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EEQ35140.1 - 0.00025 20.9 1.0 0.00086 19.1 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EEQ35140.1 - 0.055 13.4 1.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.16 EEQ35140.1 - 0.09 11.9 1.7 0.3 10.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APH PF01636.18 EEQ35141.1 - 7.7e-15 55.2 0.0 1.2e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35141.1 - 2.7e-06 27.1 0.0 3.8e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ35141.1 - 0.0049 16.0 0.0 2.2 7.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain PIP49_C PF12260.3 EEQ35141.1 - 0.05 13.0 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 WaaY PF06176.6 EEQ35141.1 - 0.2 10.8 0.0 0.37 9.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Peptidase_S8 PF00082.17 EEQ35142.1 - 1.3e-36 126.1 14.7 1.9e-36 125.6 10.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ35142.1 - 5.9e-14 52.3 0.1 1.4e-13 51.2 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 SNARE PF05739.14 EEQ35144.1 - 3.1e-15 55.5 2.1 7.4e-15 54.3 0.8 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EEQ35144.1 - 0.064 13.4 0.7 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Syntaxin PilJ PF13675.1 EEQ35144.1 - 0.12 12.6 5.8 0.076 13.3 0.5 2.4 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term zf-RING_2 PF13639.1 EEQ35145.1 - 2e-06 27.4 15.1 2e-06 27.4 10.4 2.9 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ35145.1 - 6.5e-05 22.5 11.9 6.5e-05 22.5 8.2 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEQ35145.1 - 0.00047 19.8 9.9 0.0015 18.2 6.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EEQ35145.1 - 0.0006 19.4 14.1 0.0006 19.4 9.7 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-TRAF PF02176.13 EEQ35145.1 - 0.0018 18.5 0.8 0.0018 18.5 0.6 3.4 3 1 1 4 4 3 2 TRAF-type zinc finger zf-C3HC4_4 PF15227.1 EEQ35145.1 - 0.0022 17.8 14.8 0.0094 15.8 10.3 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EEQ35145.1 - 0.0032 17.4 15.1 0.0032 17.4 10.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ35145.1 - 0.0072 15.9 14.8 0.0072 15.9 10.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) TSC22 PF01166.13 EEQ35145.1 - 0.032 14.1 1.2 3.5 7.6 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF2360 PF10152.4 EEQ35145.1 - 0.3 11.3 4.8 0.41 10.9 2.9 1.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) TMF_DNA_bd PF12329.3 EEQ35145.1 - 0.45 10.3 3.9 0.7 9.7 0.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.3 EEQ35145.1 - 0.47 10.1 6.1 1 9.1 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Rep_fac-A_C PF08646.5 EEQ35145.1 - 2.4 7.8 8.4 0.16 11.7 0.9 2.3 2 0 0 2 2 2 0 Replication factor-A C terminal domain Het-C PF07217.6 EEQ35148.1 - 7.6e-281 932.6 0.0 9.1e-281 932.4 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C BRO1 PF03097.13 EEQ35150.1 - 0.031 13.0 0.2 0.038 12.7 0.1 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF4616 PF15394.1 EEQ35150.1 - 0.099 11.6 3.0 0.21 10.5 2.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4616) Ank_2 PF12796.2 EEQ35151.1 - 6.1e-50 167.5 1.2 1.1e-16 60.8 0.1 8.9 5 2 4 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ35151.1 - 1.4e-37 125.6 3.1 1.4e-06 27.8 0.0 11.4 12 1 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.1 EEQ35151.1 - 8.9e-36 121.6 2.8 1e-08 35.4 0.0 11.4 9 3 2 11 11 11 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ35151.1 - 1.5e-30 104.4 9.4 0.00034 20.7 0.0 10.6 10 1 1 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ35151.1 - 2.1e-30 101.7 2.9 0.00044 20.2 0.0 13.2 14 0 0 14 14 14 5 Ankyrin repeat IBN_N PF03810.14 EEQ35152.1 - 6.9e-10 38.7 1.2 8.4e-08 32.0 0.1 3.5 2 1 1 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EEQ35152.1 - 0.0001 22.2 0.1 0.02 14.8 0.0 3.8 3 1 0 3 3 3 1 Exportin 1-like protein CAS_CSE1 PF03378.10 EEQ35152.1 - 0.00027 19.3 0.1 0.00067 18.0 0.0 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Proteasom_PSMB PF10508.4 EEQ35152.1 - 0.0055 15.0 0.0 0.015 13.5 0.0 1.7 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HORMA PF02301.13 EEQ35153.1 - 1.1e-20 74.0 0.0 2.1e-20 73.1 0.0 1.4 2 0 0 2 2 2 1 HORMA domain IBR PF01485.16 EEQ35154.1 - 0.00035 20.3 20.4 0.13 12.1 0.3 3.7 3 0 0 3 3 3 3 IBR domain Cu-oxidase PF00394.17 EEQ35155.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase Acetyltransf_7 PF13508.1 EEQ35156.1 - 2.3e-05 24.4 0.0 5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ35156.1 - 0.00012 21.9 0.2 0.00027 20.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ35156.1 - 0.00092 19.2 0.1 0.0033 17.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEQ35156.1 - 0.002 17.8 0.0 0.0046 16.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ35156.1 - 0.015 15.4 0.0 0.094 12.8 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2036 PF09724.4 EEQ35157.1 - 1e-14 54.4 0.2 7.7e-14 51.5 0.2 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Anp1 PF03452.9 EEQ35158.1 - 1.7e-119 397.9 1.0 4.5e-119 396.5 0.0 1.9 2 0 0 2 2 2 1 Anp1 DUF2146 PF10220.4 EEQ35158.1 - 0.28 9.0 13.9 1.8 6.4 10.4 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2146) tRNA_bind PF01588.15 EEQ35159.1 - 2.2e-19 69.1 0.0 9.2e-18 63.8 0.0 2.6 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EEQ35159.1 - 2.7e-09 37.3 0.0 5.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ35159.1 - 0.0064 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PGP_phosphatase PF09419.5 EEQ35159.1 - 0.066 12.5 0.1 0.22 10.8 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase RR_TM4-6 PF06459.7 EEQ35159.1 - 0.31 10.8 6.4 0.51 10.1 4.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp PF00026.18 EEQ35160.1 - 1.1e-63 215.3 0.0 1.3e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEQ35160.1 - 5.9e-08 33.0 0.5 0.0007 20.0 0.2 2.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EEQ35160.1 - 0.00016 21.6 0.0 0.0023 17.9 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EEQ35160.1 - 0.0035 17.1 0.0 0.055 13.2 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EEQ35160.1 - 0.035 14.0 0.2 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease TAXi_C PF14541.1 EEQ35160.1 - 0.11 11.9 0.1 0.95 8.9 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal APH PF01636.18 EEQ35161.1 - 5.3e-11 42.6 0.0 4.2e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ35161.1 - 0.00019 20.1 0.0 0.21 10.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEQ35161.1 - 0.083 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.18 EEQ35162.1 - 2.1e-15 57.1 0.0 3.5e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35162.1 - 0.00018 21.1 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase TraU PF06834.6 EEQ35162.1 - 0.033 13.2 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 TraU protein Fructosamin_kin PF03881.9 EEQ35162.1 - 0.048 12.6 0.0 0.47 9.3 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase EDR1 PF14381.1 EEQ35162.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 VRP1 PF03538.9 EEQ35163.1 - 0.00068 18.7 1.5 0.00079 18.5 1.0 1.0 1 0 0 1 1 1 1 Salmonella virulence plasmid 28.1kDa A protein Phage_int_SAM_4 PF13495.1 EEQ35163.1 - 0.0087 16.3 0.7 0.0087 16.3 0.5 1.1 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain ATG16 PF08614.6 EEQ35163.1 - 0.013 15.3 6.1 0.013 15.3 4.2 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.1 EEQ35163.1 - 0.014 15.6 5.2 0.016 15.5 3.6 1.1 1 0 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.10 EEQ35163.1 - 0.015 14.7 6.1 0.61 9.6 0.3 2.1 1 1 1 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.4 EEQ35163.1 - 0.029 14.5 4.2 0.041 14.0 1.7 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med9 PF07544.8 EEQ35163.1 - 0.04 13.6 4.2 0.45 10.2 0.1 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4558 PF15104.1 EEQ35163.1 - 0.042 13.7 1.4 0.042 13.7 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4558) Imm25 PF15571.1 EEQ35163.1 - 0.061 13.4 0.4 0.068 13.2 0.3 1.1 1 0 0 1 1 1 0 Immunity protein 25 LXG PF04740.7 EEQ35163.1 - 0.066 12.9 1.7 0.084 12.6 1.2 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily CENP-F_leu_zip PF10473.4 EEQ35163.1 - 0.096 12.5 6.3 0.11 12.3 4.4 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2721 PF11026.3 EEQ35163.1 - 0.1 12.2 1.9 0.13 11.9 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) ECM11 PF15463.1 EEQ35163.1 - 0.12 12.6 3.3 0.14 12.4 2.3 1.2 1 0 0 1 1 1 0 Extracellular mutant protein 11 DUF972 PF06156.8 EEQ35163.1 - 0.16 12.3 2.1 0.17 12.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 EEQ35163.1 - 0.16 11.7 2.5 0.17 11.7 1.8 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.15 EEQ35163.1 - 0.24 11.1 8.6 0.76 9.5 2.8 2.0 1 1 1 2 2 2 0 Prefoldin subunit Sec8_exocyst PF04048.9 EEQ35163.1 - 0.35 10.5 3.6 0.59 9.7 0.9 1.9 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Cortex-I_coil PF09304.5 EEQ35163.1 - 0.41 10.7 4.5 0.53 10.3 3.1 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil TBPIP PF07106.8 EEQ35163.1 - 0.46 10.0 5.0 0.53 9.8 3.5 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fmp27_WPPW PF10359.4 EEQ35163.1 - 0.49 8.7 4.3 0.5 8.7 3.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Enkurin PF13864.1 EEQ35163.1 - 0.58 10.3 5.0 0.8 9.9 3.4 1.3 1 0 0 1 1 1 0 Calmodulin-binding Syntaxin PF00804.20 EEQ35163.1 - 0.83 9.8 4.5 0.98 9.6 3.1 1.2 1 0 0 1 1 1 0 Syntaxin TMF_DNA_bd PF12329.3 EEQ35163.1 - 1.3 8.8 5.4 2.9 7.7 3.8 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 EEQ35163.1 - 1.4 9.3 5.5 14 6.2 3.8 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Retrotrans_gag PF03732.12 EEQ35163.1 - 2.8 8.0 4.9 6.4 6.9 1.9 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein Shugoshin_N PF07558.6 EEQ35163.1 - 4.1 7.1 7.3 7.7 6.3 0.2 2.6 3 0 0 3 3 2 0 Shugoshin N-terminal coiled-coil region ParA PF10609.4 EEQ35164.1 - 2.1e-35 120.4 0.0 3.8e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEQ35164.1 - 5.2e-17 61.9 0.0 7.2e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEQ35164.1 - 5.1e-07 29.7 0.0 3.9e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EEQ35164.1 - 6.3e-06 25.4 0.2 0.00041 19.4 0.0 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EEQ35164.1 - 0.00024 20.2 0.0 0.00045 19.3 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EEQ35164.1 - 0.0042 16.7 0.1 1.4 8.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEQ35164.1 - 0.014 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEQ35164.1 - 0.029 13.7 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ35164.1 - 0.08 13.7 0.0 0.12 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.2 EEQ35164.1 - 0.1 12.4 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain RNA_helicase PF00910.17 EEQ35164.1 - 0.12 12.5 0.1 0.27 11.4 0.1 1.6 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EEQ35164.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EEQ35164.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PEMT PF04191.8 EEQ35165.1 - 3.1e-59 197.6 9.0 5.1e-36 123.0 0.5 3.0 2 0 0 2 2 2 2 Phospholipid methyltransferase RNase_PH PF01138.16 EEQ35166.1 - 2.6e-26 92.4 0.0 6e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Choline_kinase PF01633.15 EEQ35169.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA-synt_2b PF00587.20 EEQ35170.1 - 3.7e-22 78.7 0.0 5.8e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EEQ35170.1 - 3.2e-21 75.0 3.5 7.8e-21 73.7 2.5 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EEQ35170.1 - 2.3e-12 46.6 0.0 4.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 EEQ35171.1 - 4.3e-143 477.4 13.7 5e-143 477.2 9.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 EEQ35172.1 - 1.1e-20 72.6 11.4 3e-06 26.8 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EEQ35172.1 - 0.00014 20.1 0.2 0.00022 19.5 0.2 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 S1 PF00575.18 EEQ35173.1 - 8.3e-80 262.9 40.5 1.2e-15 57.3 0.1 13.0 12 2 0 12 12 12 11 S1 RNA binding domain TPR_14 PF13428.1 EEQ35173.1 - 2.7e-07 30.6 0.0 0.77 10.5 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ35173.1 - 6.3e-07 29.8 0.0 1.1 9.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ35173.1 - 2.5e-06 27.7 0.3 0.051 13.9 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.9 EEQ35173.1 - 4.3e-05 23.3 11.8 0.002 17.9 0.0 4.4 2 2 1 4 4 3 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EEQ35173.1 - 0.00088 18.8 0.1 0.49 10.0 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.1 EEQ35173.1 - 0.0059 16.3 0.0 0.047 13.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ35173.1 - 0.012 15.5 0.1 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 EEQ35173.1 - 0.042 13.8 0.0 9.3 6.4 0.0 3.1 2 0 0 2 2 2 0 PPR repeat TPR_2 PF07719.12 EEQ35173.1 - 0.048 13.5 2.1 0.55 10.2 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ35173.1 - 0.083 13.3 1.6 21 5.8 0.1 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat YajC PF02699.10 EEQ35173.1 - 0.59 9.8 7.9 9.1 6.0 0.2 4.1 4 0 0 4 4 4 0 Preprotein translocase subunit Phage_lysozyme PF00959.14 EEQ35175.1 - 1.7e-14 54.0 0.0 2.3e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme UreD PF01774.12 EEQ35176.1 - 3.7e-51 173.5 0.0 5.3e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 EEQ35177.1 - 1.2e-38 131.4 0.3 4.1e-38 129.7 0.2 2.0 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 EEQ35177.1 - 0.00013 22.1 0.0 0.063 13.5 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats DUF422 PF04240.7 EEQ35177.1 - 0.046 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) DUF3573 PF12097.3 EEQ35177.1 - 0.17 10.4 0.9 0.29 9.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) GFA PF04828.9 EEQ35178.1 - 9.2e-15 54.3 3.7 1.2e-14 53.9 2.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Acatn PF13000.2 EEQ35179.1 - 3e-146 488.1 21.2 5.1e-78 262.9 6.2 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 ATG27 PF09451.5 EEQ35179.1 - 0.35 10.0 0.7 0.59 9.3 0.5 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Pkinase PF00069.20 EEQ35180.1 - 3.6e-09 36.1 0.0 1.7e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35180.1 - 0.003 16.6 0.0 0.017 14.1 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase CENP-O PF09496.5 EEQ35181.1 - 5.2e-28 97.1 0.4 9e-28 96.3 0.0 1.6 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DUF4140 PF13600.1 EEQ35181.1 - 1 9.8 5.8 4.3 7.8 0.6 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Kinetocho_Slk19 PF12709.2 EEQ35183.1 - 0.024 14.6 2.1 0.024 14.6 1.5 2.6 2 1 0 2 2 2 0 Central kinetochore-associated DFP PF04127.10 EEQ35185.1 - 1.5e-12 47.4 0.0 0.00025 20.7 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Polysacc_deac_1 PF01522.16 EEQ35186.1 - 4.6e-12 45.6 0.0 1e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide deacetylase Phage_DNA_bind PF02303.12 EEQ35186.1 - 0.051 13.6 0.0 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Helix-destabilising protein DEAD PF00270.24 EEQ35187.1 - 1.2e-25 89.9 0.0 1.7e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ35187.1 - 4.3e-15 55.3 0.1 1.1e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ35187.1 - 5e-05 22.2 0.0 6.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1929 PF09118.6 EEQ35188.1 - 5.2e-22 77.7 0.0 8.8e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) AIF-MLS PF14962.1 EEQ35188.1 - 0.013 15.1 0.1 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence RCC1_2 PF13540.1 EEQ35188.1 - 0.028 14.0 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Fumble PF03630.9 EEQ35189.1 - 3.4e-134 447.0 1.3 3.8e-133 443.5 0.9 1.9 1 1 0 1 1 1 1 Fumble GPI2 PF06432.6 EEQ35190.1 - 9.9e-67 225.2 9.9 1.1e-66 225.1 6.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Adeno_E1A PF02703.9 EEQ35191.1 - 0.085 12.2 2.0 0.13 11.7 1.4 1.4 1 1 0 1 1 1 0 Early E1A protein AF1Q PF15017.1 EEQ35191.1 - 2.2 8.2 6.9 0.44 10.4 0.2 2.2 1 1 1 2 2 2 0 Drug resistance and apoptosis regulator Glyco_hydro_18 PF00704.23 EEQ35194.1 - 1.2e-16 61.1 0.0 5.2e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 NhaB PF06450.7 EEQ35195.1 - 0.091 11.3 0.0 0.091 11.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial Na+/H+ antiporter B (NhaB) UAE_UbL PF14732.1 EEQ35196.1 - 0.076 13.1 0.2 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain AA_permease_2 PF13520.1 EEQ35198.1 - 4.4e-46 157.2 57.4 5.6e-46 156.9 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ35198.1 - 2.3e-21 75.7 51.4 3.2e-21 75.2 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease Dynamin_N PF00350.18 EEQ35200.1 - 8e-26 90.8 0.0 2e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ35200.1 - 5.7e-16 58.1 2.8 7e-16 57.8 0.2 2.2 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EEQ35200.1 - 0.00016 21.6 0.1 0.0018 18.1 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase TFIIA PF03153.8 EEQ35200.1 - 0.00085 19.3 15.3 0.00085 19.3 10.6 1.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 EEQ35200.1 - 0.028 12.9 15.0 0.053 12.0 10.4 1.4 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 EEQ35200.1 - 0.034 12.2 9.6 0.062 11.4 6.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Miro PF08477.8 EEQ35200.1 - 0.075 13.5 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Nop14 PF04147.7 EEQ35200.1 - 3.2 5.5 29.0 5.9 4.6 20.1 1.3 1 0 0 1 1 1 0 Nop14-like family 5_nucleotid_C PF02872.13 EEQ35202.1 - 3.6e-35 121.2 0.0 6.3e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EEQ35202.1 - 0.089 12.1 0.4 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Kinetochor_Ybp2 PF08568.5 EEQ35203.1 - 0.022 12.9 0.0 0.022 12.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Herpes_gE PF02480.11 EEQ35203.1 - 0.026 12.7 0.0 0.026 12.7 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MacB_PCD PF12704.2 EEQ35203.1 - 0.05 13.1 0.0 0.054 13.0 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain TMEM51 PF15345.1 EEQ35203.1 - 0.061 13.0 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3357 PF11837.3 EEQ35203.1 - 0.078 12.8 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) PIRT PF15099.1 EEQ35203.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Peptidase_M50 PF02163.17 EEQ35203.1 - 0.14 11.1 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 Aldedh PF00171.17 EEQ35204.1 - 9e-152 505.6 0.2 1e-151 505.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 EEQ35204.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase BTB PF00651.26 EEQ35205.1 - 0.05 13.5 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Annexin PF00191.15 EEQ35205.1 - 0.055 13.3 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 Annexin Gln-synt_C PF00120.19 EEQ35209.1 - 1.1e-42 145.9 0.0 2.2e-42 144.9 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EEQ35209.1 - 1.9e-26 93.2 0.0 4.4e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EEQ35210.1 - 4.6e-37 127.5 20.4 4.6e-37 127.5 14.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ35210.1 - 7.1e-12 44.6 15.3 7.1e-12 44.6 10.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EEQ35210.1 - 0.0022 16.3 4.1 0.0036 15.5 2.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0016 PF01169.14 EEQ35213.1 - 7.4e-39 131.7 25.6 5.6e-21 74.4 5.3 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF4614 PF15391.1 EEQ35213.1 - 0.31 10.7 2.3 0.33 10.7 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) Myb_DNA-binding PF00249.26 EEQ35214.1 - 0.005 16.8 0.1 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain PBP1_TM PF14812.1 EEQ35214.1 - 0.01 16.1 5.1 0.05 13.9 3.5 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EEQ35214.1 - 0.05 13.1 3.7 0.11 11.9 2.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EEQ35214.1 - 0.83 9.2 5.2 2.2 7.8 2.4 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.1 EEQ35214.1 - 3.3 7.9 8.8 14 5.8 6.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Annexin PF00191.15 EEQ35215.1 - 3.5e-13 49.2 3.6 0.0038 17.1 0.1 4.4 4 0 0 4 4 4 4 Annexin Ribosomal_L21e PF01157.13 EEQ35216.1 - 7.6e-40 134.7 4.2 1.4e-39 133.8 2.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e Ter PF05472.6 EEQ35216.1 - 0.068 12.2 0.7 0.087 11.9 0.5 1.1 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Ribosomal_S4 PF00163.14 EEQ35217.1 - 1.2e-30 105.6 1.0 2.5e-30 104.7 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EEQ35217.1 - 8.4e-13 47.5 1.3 8.4e-13 47.5 0.9 2.3 3 0 0 3 3 3 1 S4 domain Bacillus_HBL PF05791.6 EEQ35218.1 - 0.0039 16.5 2.8 0.0079 15.5 0.2 2.1 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Atg14 PF10186.4 EEQ35218.1 - 0.0076 15.2 7.9 0.0076 15.2 5.4 2.1 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 EEQ35218.1 - 0.018 14.8 3.9 0.046 13.5 0.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.1 EEQ35218.1 - 0.024 13.5 7.6 0.044 12.7 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 EEQ35218.1 - 0.025 13.0 8.0 0.037 12.5 5.5 1.3 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 EEQ35218.1 - 0.031 14.4 2.7 0.031 14.4 1.9 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3552 PF12072.3 EEQ35218.1 - 0.035 13.2 20.4 0.071 12.3 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) CENP-F_leu_zip PF10473.4 EEQ35218.1 - 0.05 13.4 16.1 0.16 11.7 1.1 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ExbD PF02472.11 EEQ35218.1 - 0.076 13.0 0.4 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF1043 PF06295.7 EEQ35218.1 - 0.086 12.4 4.2 0.072 12.7 1.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) TPR_10 PF13374.1 EEQ35218.1 - 0.11 12.4 0.7 0.58 10.1 0.5 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat GLE1 PF07817.8 EEQ35218.1 - 0.16 10.9 1.6 0.21 10.4 0.3 1.6 1 1 0 2 2 2 0 GLE1-like protein Exonuc_VII_L PF02601.10 EEQ35218.1 - 0.17 11.0 9.7 0.23 10.6 6.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3103 PF11301.3 EEQ35218.1 - 0.17 10.5 1.7 0.21 10.2 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3103) Spc7 PF08317.6 EEQ35218.1 - 0.21 10.2 17.0 0.047 12.3 4.0 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein Prefoldin PF02996.12 EEQ35218.1 - 0.42 10.2 15.6 0.035 13.7 1.8 3.7 2 2 2 4 4 4 0 Prefoldin subunit DUF948 PF06103.6 EEQ35218.1 - 0.42 10.4 4.2 4 7.3 0.4 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.6 EEQ35218.1 - 0.66 9.9 7.3 4 7.3 2.1 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.9 EEQ35218.1 - 0.74 9.2 4.9 0.38 10.1 0.1 2.7 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain ATG16 PF08614.6 EEQ35218.1 - 0.89 9.3 23.8 1.2 8.9 3.1 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF1216 PF06746.6 EEQ35218.1 - 0.98 9.2 5.0 0.23 11.2 1.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1216) zf-C4H2 PF10146.4 EEQ35218.1 - 1.5 8.7 9.6 0.44 10.5 3.2 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Microtub_assoc PF07989.6 EEQ35218.1 - 1.5 8.6 10.5 0.43 10.4 2.5 3.4 1 1 2 4 4 4 0 Microtubule associated TBPIP PF07106.8 EEQ35218.1 - 1.7 8.2 13.9 0.2 11.1 3.7 2.5 3 0 0 3 3 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 EEQ35218.1 - 1.7 7.7 5.6 2.4 7.2 0.6 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ISG65-75 PF11727.3 EEQ35218.1 - 1.9 7.5 11.9 0.65 8.9 1.8 2.6 1 1 0 2 2 2 0 Invariant surface glycoprotein FtsK_SpoIIIE PF01580.13 EEQ35218.1 - 2.4 7.5 6.9 2.9 7.3 0.2 2.1 1 1 1 2 2 2 0 FtsK/SpoIIIE family Prefoldin_2 PF01920.15 EEQ35218.1 - 2.4 7.9 17.4 1 9.1 3.6 3.5 3 1 0 3 3 2 0 Prefoldin subunit Cep57_CLD_2 PF14197.1 EEQ35218.1 - 2.5 8.1 15.0 0.46 10.4 0.8 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 PEARLI-4 PF05278.7 EEQ35218.1 - 2.8 7.2 11.3 0.29 10.4 1.4 2.2 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Strep_SA_rep PF06696.6 EEQ35218.1 - 3.2 7.6 6.3 1.5 8.6 1.1 2.9 3 0 0 3 3 2 0 Streptococcal surface antigen repeat DUF4200 PF13863.1 EEQ35218.1 - 3.2 7.7 22.6 2.4 8.1 6.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Filament PF00038.16 EEQ35218.1 - 3.6 6.9 19.2 11 5.3 13.3 1.8 1 1 0 1 1 1 0 Intermediate filament protein ING PF12998.2 EEQ35218.1 - 4 7.7 9.3 13 6.1 0.3 3.0 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Fib_alpha PF08702.5 EEQ35218.1 - 4.3 7.4 6.9 3.6 7.6 1.9 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Fmp27_WPPW PF10359.4 EEQ35218.1 - 5.7 5.2 11.5 0.44 8.8 3.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Spc24 PF08286.6 EEQ35218.1 - 9.7 5.9 16.3 1.3 8.6 1.8 3.2 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 MIP-T3 PF10243.4 EEQ35219.1 - 0.45 8.9 30.6 0.55 8.6 21.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 EEQ35219.1 - 2.4 7.4 18.5 3.4 6.9 12.8 1.3 1 0 0 1 1 1 0 Vta1 like Amidoligase_2 PF12224.3 EEQ35220.1 - 9.4e-12 45.0 0.0 3.2e-05 23.6 0.0 2.9 2 1 0 2 2 2 2 Putative amidoligase enzyme DUF946 PF06101.6 EEQ35222.1 - 0.00019 19.5 0.1 0.021 12.8 0.0 2.1 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) Septin PF00735.13 EEQ35223.1 - 4e-32 111.3 0.0 5.8e-13 48.4 0.0 3.1 3 0 0 3 3 3 3 Septin Miro PF08477.8 EEQ35223.1 - 0.02 15.3 0.0 0.07 13.6 0.0 1.9 2 1 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 EEQ35223.1 - 0.024 14.9 0.0 0.18 12.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 EEQ35224.1 - 1.1e-77 255.8 2.0 1.5e-26 91.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 EEQ35224.1 - 0.021 14.2 0.0 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Di19_C PF14571.1 EEQ35225.1 - 1.8 8.8 15.1 1 9.6 3.0 2.3 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Conotoxin PF02950.12 EEQ35225.1 - 2.4 9.0 6.1 0.74 10.6 0.3 2.5 3 0 0 3 3 3 0 Conotoxin Imm34 PF15596.1 EEQ35227.1 - 0.033 14.3 1.3 3.1 7.9 0.0 2.8 2 1 1 3 3 3 0 Immunity protein 34 SecE PF00584.15 EEQ35228.1 - 4.8e-12 45.2 0.0 6.2e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 EEQ35229.1 - 6.6e-10 38.8 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ35229.1 - 2.5e-07 30.2 0.0 4.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ35229.1 - 0.0055 16.5 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EEQ35230.1 - 2.1e-24 84.4 15.2 4.4e-06 26.3 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EEQ35230.1 - 1.3e-05 23.6 2.9 0.12 10.6 0.0 4.4 3 1 2 5 5 5 3 Cytochrome D1 heme domain PQQ_3 PF13570.1 EEQ35230.1 - 0.005 17.0 1.8 4.4 7.7 0.0 4.4 4 0 0 4 4 4 1 PQQ-like domain PD40 PF07676.7 EEQ35230.1 - 0.048 13.3 1.9 0.34 10.6 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat BBS2_N PF14781.1 EEQ35230.1 - 0.14 11.7 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal PX PF00787.19 EEQ35231.1 - 1.3e-26 92.6 0.2 1.5e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 EEQ35231.1 - 0.059 12.4 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus Myb_DNA-bind_6 PF13921.1 EEQ35232.1 - 1e-13 51.1 0.0 9e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ35232.1 - 2.9e-10 40.0 0.4 4.1e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain RasGEF PF00617.14 EEQ35234.1 - 7.2e-05 22.5 0.0 0.00043 20.0 0.0 2.3 1 1 0 1 1 1 1 RasGEF domain DNA_pol_B PF00136.16 EEQ35239.1 - 2.7e-93 313.3 0.0 3.9e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EEQ35239.1 - 1.3e-18 66.9 0.1 7e-15 54.7 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EEQ35239.1 - 3.4e-18 65.3 7.7 3.4e-18 65.3 5.4 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.3 EEQ35240.1 - 7.4e-78 261.5 17.5 7.4e-78 261.5 12.2 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EEQ35240.1 - 0.0099 15.5 0.9 0.021 14.4 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Ribosomal_L37e PF01907.14 EEQ35241.1 - 9.2e-28 95.8 8.9 1.4e-27 95.1 6.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EEQ35241.1 - 0.0045 16.7 1.1 0.0069 16.1 0.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon Ribosomal_S14 PF00253.16 EEQ35241.1 - 0.12 11.7 0.3 0.12 11.7 0.2 2.6 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e DUF1462 PF07315.6 EEQ35241.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Ribosomal_L40e PF01020.12 EEQ35241.1 - 0.6 9.7 7.0 7 6.3 1.6 2.3 1 1 1 2 2 2 0 Ribosomal L40e family GATA PF00320.22 EEQ35241.1 - 0.72 9.2 6.1 0.8 9.1 0.5 2.4 1 1 1 2 2 2 0 GATA zinc finger DUF2348 PF09807.4 EEQ35242.1 - 8.7e-08 31.5 0.0 0.0004 19.5 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 EEQ35242.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC RdRP PF05183.7 EEQ35243.1 - 1.8e-187 624.6 0.0 2.4e-187 624.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.16 EEQ35244.1 - 3.2e-133 444.5 44.5 3.9e-133 444.2 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ35244.1 - 7.6e-37 126.8 48.2 9.3e-37 126.5 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.15 EEQ35246.1 - 3e-80 269.2 9.6 5.4e-80 268.3 6.7 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EEQ35246.1 - 3.9e-30 103.3 2.5 3.9e-30 103.3 1.8 3.0 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EEQ35246.1 - 7.4e-08 31.8 0.0 1.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain FAD-oxidase_C PF02913.14 EEQ35247.1 - 7.2e-59 199.1 0.0 9.3e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EEQ35247.1 - 8.2e-35 119.3 0.0 2.8e-34 117.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Ribosomal_S4e PF00900.15 EEQ35248.1 - 1.2e-31 108.1 0.5 2.4e-31 107.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EEQ35248.1 - 5.9e-19 67.6 4.9 1.2e-18 66.6 3.4 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EEQ35248.1 - 6.2e-05 22.3 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EEQ35248.1 - 0.012 15.3 0.8 0.012 15.3 0.5 3.2 4 0 0 4 4 4 0 KOW motif MAT_Alpha1 PF04769.7 EEQ35250.1 - 1.4e-30 106.1 0.0 2.4e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 DUF605 PF04652.11 EEQ35250.1 - 2.4 7.4 14.0 0.11 11.8 5.7 1.6 2 0 0 2 2 2 0 Vta1 like Exo_endo_phos_2 PF14529.1 EEQ35252.1 - 1.2e-16 60.3 0.0 7.4e-16 57.8 0.0 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EEQ35252.1 - 5.2e-13 49.5 0.0 9.2e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EEQ35252.1 - 0.017 15.0 1.2 0.044 13.7 0.9 1.8 1 0 0 1 1 1 0 GRF zinc finger COX6A PF02046.10 EEQ35253.1 - 2.6e-37 127.2 2.9 5.3e-37 126.2 2.0 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa ANTH PF07651.11 EEQ35254.1 - 1.1e-75 253.9 0.0 1.1e-75 253.9 0.0 2.7 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 EEQ35254.1 - 5.8e-64 214.6 8.0 5.8e-64 214.6 5.5 5.5 4 1 1 6 6 6 1 I/LWEQ domain DUF2404 PF10296.4 EEQ35255.1 - 1.1e-28 99.2 0.0 1.8e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) SKG6 PF08693.5 EEQ35257.1 - 0.00071 18.8 0.3 0.0013 17.9 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 EEQ35257.1 - 0.0085 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Med12 PF09497.5 EEQ35258.1 - 3.4e-28 97.4 0.2 1.2e-27 95.6 0.1 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 EEQ35258.1 - 0.00077 18.0 0.0 0.019 13.4 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain CIA30 PF08547.7 EEQ35259.1 - 6.6e-37 126.7 0.0 2.1e-23 82.9 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.13 EEQ35260.1 - 3.3e-84 281.8 0.0 3.9e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Apc5 PF12862.2 EEQ35261.1 - 2e-33 114.0 3.1 2.7e-33 113.6 0.8 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 Cohesin_load PF10345.4 EEQ35261.1 - 0.00034 18.9 1.0 0.43 8.7 0.0 2.2 2 0 0 2 2 2 2 Cohesin loading factor TPR_12 PF13424.1 EEQ35261.1 - 0.0031 17.4 7.3 1.7 8.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ35261.1 - 0.013 15.7 6.6 0.5 10.7 0.1 5.0 4 1 2 6 6 6 0 Tetratricopeptide repeat SUI1 PF01253.17 EEQ35262.1 - 1.8e-29 101.3 6.2 2.3e-29 100.9 4.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 EOS1 PF12326.3 EEQ35263.1 - 3.6e-29 101.3 16.5 9.4e-25 86.9 7.8 2.3 1 1 1 2 2 2 2 N-glycosylation protein MBA1 PF07961.6 EEQ35265.1 - 2e-11 43.2 0.1 4.3e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EEQ35265.1 - 0.00096 19.1 0.1 0.0059 16.6 0.1 2.0 1 1 0 1 1 1 1 Tim44-like domain SSF PF00474.12 EEQ35266.1 - 0.00059 18.5 25.8 0.0029 16.3 17.9 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family Glycoprotein_B PF00606.13 EEQ35266.1 - 5.9 4.7 4.9 10 4.0 3.4 1.3 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B RhoGAP PF00620.22 EEQ35267.1 - 1.5e-48 164.3 0.0 3.4e-48 163.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EEQ35267.1 - 9.5e-15 54.5 2.6 1.9e-14 53.6 0.2 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain ABM PF03992.11 EEQ35268.1 - 2e-13 50.1 0.0 2.4e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SchA_CurD PF04486.7 EEQ35268.1 - 0.00078 19.2 0.0 0.001 18.9 0.0 1.1 1 0 0 1 1 1 1 SchA/CurD like domain Ras PF00071.17 EEQ35269.1 - 2.5e-55 186.2 0.0 2.9e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ35269.1 - 5.2e-18 65.6 0.0 7.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ35269.1 - 4e-08 32.7 0.0 5.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MAM1 PF10434.4 EEQ35269.1 - 0.078 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex protein MAM1 RRM_6 PF14259.1 EEQ35270.1 - 2.4e-11 43.4 0.0 4.9e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ35270.1 - 5.8e-11 41.8 0.0 5.8e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ35270.1 - 0.0036 17.1 0.8 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.1 EEQ35271.1 - 2.7e-79 265.7 0.7 3.3e-79 265.5 0.5 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EEQ35271.1 - 3.9e-05 23.2 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-T PF15511.1 EEQ35272.1 - 1.5e-99 334.0 22.2 1.5e-99 334.0 15.4 2.1 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EEQ35272.1 - 7.1e-07 29.3 0.1 1.4e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EEQ35272.1 - 3e-05 24.0 0.1 5.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEQ35272.1 - 0.00041 20.3 0.0 0.00065 19.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNA_pol_Rpc4 PF05132.9 EEQ35272.1 - 0.0074 16.2 0.4 0.014 15.4 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase III RPC4 SURF1 PF02104.10 EEQ35273.1 - 8.1e-65 218.6 0.0 1.1e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 EEQ35274.1 - 2.2e-09 37.2 0.0 3.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain CDC45 PF02724.9 EEQ35274.1 - 1 7.3 5.8 1.5 6.7 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein PAT1 PF09770.4 EEQ35274.1 - 1.9 6.5 16.8 2.8 6.0 11.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2076 PF09849.4 EEQ35275.1 - 1.9e-07 31.4 10.2 2.2e-07 31.1 7.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EEQ35275.1 - 7.2e-06 25.7 2.9 1.2e-05 25.1 2.0 1.3 1 0 0 1 1 1 1 CHCH domain DUF605 PF04652.11 EEQ35275.1 - 0.49 9.7 8.0 0.71 9.2 5.5 1.2 1 0 0 1 1 1 0 Vta1 like Totivirus_coat PF05518.6 EEQ35275.1 - 2.4 5.8 11.0 2.8 5.6 7.6 1.2 1 0 0 1 1 1 0 Totivirus coat protein TFIIA PF03153.8 EEQ35275.1 - 2.7 7.7 6.4 3.3 7.5 4.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gly-zipper_OmpA PF13436.1 EEQ35275.1 - 3.2 7.4 14.2 0.69 9.5 7.4 1.7 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Sas10_Utp3 PF04000.10 EEQ35276.1 - 9.8e-14 51.3 0.9 9.8e-14 51.3 0.7 1.9 2 1 0 2 2 2 1 Sas10/Utp3/C1D family ApbA_C PF08546.6 EEQ35277.1 - 2e-31 108.5 0.1 3e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EEQ35277.1 - 4.5e-23 81.3 0.0 6e-22 77.7 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Coq4 PF05019.8 EEQ35278.1 - 6e-97 322.9 0.0 7e-97 322.6 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 EEQ35279.1 - 3.6e-30 104.1 11.1 4.6e-30 103.7 7.7 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain RelB_N PF12910.2 EEQ35279.1 - 0.022 14.1 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal DUF4615 PF15393.1 EEQ35279.1 - 0.044 14.0 0.8 0.07 13.3 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) DUF3353 PF11833.3 EEQ35279.1 - 0.39 10.1 2.4 0.36 10.2 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Sec2p PF06428.6 EEQ35280.1 - 2.2e-09 37.0 4.0 1e-08 34.9 2.5 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Myosin_tail_1 PF01576.14 EEQ35280.1 - 0.0005 17.9 7.7 0.00067 17.5 5.3 1.0 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 EEQ35280.1 - 8.5 6.1 13.0 0.26 11.1 4.1 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PRP21_like_P PF12230.3 EEQ35281.1 - 1.1e-57 195.1 11.8 5.4e-56 189.6 8.2 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EEQ35281.1 - 3.5e-26 90.6 2.8 1.8e-16 59.5 0.4 2.3 2 0 0 2 2 2 2 Surp module UPF0547 PF10571.4 EEQ35281.1 - 0.062 13.0 0.5 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 PMT PF02366.13 EEQ35282.1 - 8.7e-65 218.4 7.0 8.7e-65 218.4 4.9 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEQ35282.1 - 1.6e-55 187.6 0.0 2.4e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 MIR domain B12D PF06522.6 EEQ35283.1 - 0.12 12.0 0.2 0.2 11.4 0.1 1.5 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-DHHC PF01529.15 EEQ35284.1 - 1e-35 122.6 5.7 1e-35 122.6 3.9 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase SET PF00856.23 EEQ35285.1 - 2.4e-17 63.7 0.3 2.4e-17 63.7 0.2 3.4 3 2 0 3 3 3 1 SET domain Complex1_LYR_1 PF13232.1 EEQ35286.1 - 3.5e-16 59.1 5.5 3.5e-16 59.1 3.8 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEQ35286.1 - 4.8e-14 51.8 4.7 4.8e-14 51.8 3.3 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Nucleoplasmin PF03066.10 EEQ35286.1 - 0.043 13.3 6.1 0.014 14.9 2.0 1.8 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 EEQ35286.1 - 0.17 11.1 4.1 0.35 10.0 2.8 1.5 1 0 0 1 1 1 0 NOA36 protein PMC2NT PF08066.7 EEQ35287.1 - 0.027 14.7 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 PMC2NT (NUC016) domain ABC2_membrane_2 PF12679.2 EEQ35289.1 - 0.044 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein APH PF01636.18 EEQ35289.1 - 0.1 12.3 0.8 0.16 11.6 0.6 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family UnbV_ASPIC PF07593.7 EEQ35291.1 - 0.013 15.1 0.2 0.18 11.5 0.0 2.1 1 1 1 2 2 2 0 ASPIC and UnbV ATP-sulfurylase PF01747.12 EEQ35292.1 - 3.5e-80 268.3 0.0 5.1e-80 267.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EEQ35292.1 - 1.8e-57 193.3 0.0 2.9e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EEQ35292.1 - 5.7e-49 165.6 0.0 1.1e-48 164.6 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain PAPS_reduct PF01507.14 EEQ35293.1 - 1e-43 149.1 0.0 1.5e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.2 EEQ35294.1 - 6.8e-15 55.7 0.1 1e-14 55.1 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ35294.1 - 5.1e-13 49.9 0.4 2.9e-12 47.4 0.3 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ35294.1 - 6.1e-09 35.8 0.2 7.4e-08 32.2 0.1 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEQ35294.1 - 5.6e-06 26.6 0.0 2e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EEQ35294.1 - 0.00053 19.2 0.0 0.035 13.2 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.7 EEQ35294.1 - 0.025 13.5 0.1 0.036 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) S6PP PF05116.8 EEQ35294.1 - 0.078 12.2 0.1 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Radical_SAM PF04055.16 EEQ35295.1 - 3.6e-13 50.0 0.0 9.3e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily WD40 PF00400.27 EEQ35296.1 - 1.8e-12 46.6 8.4 3.3e-06 26.7 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EEQ35296.1 - 0.063 13.5 0.0 5.3 7.4 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain Gryzun-like PF12742.2 EEQ35296.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking FlxA PF14282.1 EEQ35296.1 - 0.49 10.3 8.5 1.3 8.9 5.9 1.7 1 0 0 1 1 1 0 FlxA-like protein IncA PF04156.9 EEQ35296.1 - 0.92 9.0 6.4 1.6 8.2 4.4 1.3 1 0 0 1 1 1 0 IncA protein DeoC PF01791.4 EEQ35299.1 - 5.4e-45 153.5 4.4 6.4e-45 153.2 3.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EEQ35299.1 - 0.00059 18.8 2.9 0.0015 17.5 1.8 1.8 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EEQ35299.1 - 0.065 12.0 2.5 0.26 10.0 1.0 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DUF2763 PF10961.3 EEQ35300.1 - 3.7e-05 24.0 7.3 8.8e-05 22.8 4.7 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF2763) GRP PF07172.6 EEQ35300.1 - 0.00022 21.6 1.7 0.00029 21.2 1.2 1.1 1 0 0 1 1 1 1 Glycine rich protein family TP_methylase PF00590.15 EEQ35301.1 - 9.5e-45 152.8 0.0 1.6e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EEQ35301.1 - 3e-12 46.6 0.0 6.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EEQ35301.1 - 5.4e-07 28.8 0.0 5.2e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal PCI PF01399.22 EEQ35302.1 - 2.4e-22 79.2 0.0 8.9e-22 77.3 0.0 2.0 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 EEQ35302.1 - 0.0012 18.2 0.5 0.15 11.3 0.1 2.4 2 0 0 2 2 2 2 Putative aspartate racemase DASH_Dad3 PF08656.5 EEQ35302.1 - 0.11 12.1 1.4 0.21 11.2 0.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 CLTH PF10607.4 EEQ35302.1 - 0.23 11.1 2.3 5.5 6.6 1.6 2.6 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain FSH1 PF03959.8 EEQ35303.1 - 1.5e-66 223.8 0.0 2.2e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EEQ35303.1 - 1.4e-09 38.2 0.2 2.4e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ35303.1 - 1.3e-07 31.5 0.1 2e-07 30.8 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EEQ35303.1 - 0.003 16.8 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EEQ35303.1 - 0.12 11.7 0.2 8.3 5.7 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Acyltransferase PF01553.16 EEQ35304.1 - 0.04 13.3 0.0 0.088 12.2 0.0 1.5 1 1 0 1 1 1 0 Acyltransferase Capsid_NCLDV PF04451.7 EEQ35306.1 - 0.058 12.3 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Med17 PF10156.4 EEQ35306.1 - 0.11 10.7 0.1 0.16 10.1 0.1 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Ribosomal_S27e PF01667.12 EEQ35307.1 - 5.9e-29 99.3 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EEQ35307.1 - 0.0082 16.0 1.3 0.0093 15.8 0.9 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EEQ35307.1 - 0.12 11.9 0.7 0.22 11.0 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger CDP-OH_P_transf PF01066.16 EEQ35309.1 - 1.5e-11 44.4 12.5 1.5e-11 44.4 8.6 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.8 EEQ35310.1 - 4.1e-39 132.6 0.4 9.2e-29 99.4 0.1 2.3 2 0 0 2 2 2 2 NIPSNAP Pyridox_oxidase PF01243.15 EEQ35311.1 - 5.1e-12 45.6 0.0 9.8e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_C65 PF10275.4 EEQ35312.1 - 3.6e-44 150.9 0.6 5.7e-44 150.2 0.4 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain Pentapeptide_3 PF13576.1 EEQ35312.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Corona_M PF01635.13 EEQ35313.1 - 0.072 12.0 6.8 0.12 11.2 0.1 2.3 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein PCI PF01399.22 EEQ35314.1 - 1.4e-16 60.6 0.3 4e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EEQ35314.1 - 3.8e-08 33.2 0.0 8.3e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_10 PF13374.1 EEQ35314.1 - 0.052 13.4 0.1 25 4.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ipi1_N PF12333.3 EEQ35314.1 - 0.074 13.0 0.1 0.73 9.8 0.0 2.3 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_12 PF13424.1 EEQ35314.1 - 0.42 10.5 2.3 2.9 7.8 0.2 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.2 EEQ35315.1 - 7.1e-178 577.5 10.9 5.4e-18 65.1 0.1 12.9 1 1 11 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ35315.1 - 2.5e-168 538.2 31.9 7.9e-09 34.8 0.0 24.2 23 1 1 24 24 24 23 Ankyrin repeat Ank_4 PF13637.1 EEQ35315.1 - 5.9e-145 469.4 59.2 1.3e-11 44.6 0.1 20.5 4 2 17 21 21 21 21 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ35315.1 - 6.4e-129 417.1 49.2 1.3e-11 44.3 0.3 20.0 2 2 20 22 22 22 22 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ35315.1 - 4.5e-112 354.5 22.6 1.8e-05 24.5 0.0 24.9 25 0 0 25 25 24 22 Ankyrin repeat Patatin PF01734.17 EEQ35315.1 - 1.2e-23 84.0 0.0 2.8e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_22 PF13401.1 EEQ35315.1 - 0.00027 21.0 0.0 0.00067 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEQ35315.1 - 0.00095 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ORC2 PF04084.9 EEQ35315.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 2 Ribosomal_L17 PF01196.14 EEQ35315.1 - 0.17 12.4 0.3 63 4.2 0.0 3.5 3 0 0 3 3 2 0 Ribosomal protein L17 DUF1187 PF06688.6 EEQ35315.1 - 1.5 8.9 19.6 47 4.2 0.0 7.9 8 0 0 8 8 8 0 Protein of unknown function (DUF1187) CWC25 PF12542.3 EEQ35316.1 - 1.8e-26 92.3 0.6 1.8e-26 92.3 0.4 3.6 4 0 0 4 4 4 2 Pre-mRNA splicing factor Cir_N PF10197.4 EEQ35316.1 - 4.7e-13 48.9 9.8 4.7e-13 48.9 6.8 3.7 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3674 PF12426.3 EEQ35316.1 - 0.14 11.5 0.6 0.46 9.9 0.1 2.1 2 0 0 2 2 2 0 RNA dependent RNA polymerase Ras PF00071.17 EEQ35317.1 - 9.4e-36 122.6 0.1 8.4e-35 119.5 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEQ35317.1 - 2.5e-14 53.7 0.0 4.1e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ35317.1 - 8e-06 25.2 0.4 0.00031 20.0 0.3 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ35317.1 - 0.00029 20.0 0.0 0.00091 18.4 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ35317.1 - 0.0075 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEQ35317.1 - 0.091 11.9 0.0 0.21 10.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EEQ35317.1 - 0.097 11.8 0.1 0.23 10.6 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EEQ35317.1 - 0.1 12.8 0.1 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 ABC transporter BPL_LplA_LipB PF03099.14 EEQ35318.1 - 9.2e-09 35.3 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family APH PF01636.18 EEQ35319.1 - 1.6e-12 47.6 0.4 6.4e-12 45.7 0.3 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35319.1 - 3.6e-06 26.6 0.0 8.8e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Ank PF00023.25 EEQ35320.1 - 5.2e-28 95.4 0.0 3.9e-07 29.5 0.0 4.6 4 1 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EEQ35320.1 - 2.5e-25 88.6 6.9 6.5e-12 45.6 0.4 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ35320.1 - 3.9e-19 68.6 10.0 7.5e-07 29.5 0.6 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ35320.1 - 5e-16 57.2 1.5 0.0046 17.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EEQ35320.1 - 1.7e-15 56.6 4.2 0.00034 20.7 0.4 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) polyprenyl_synt PF00348.12 EEQ35321.1 - 4.1e-46 156.9 0.0 4.8e-43 146.8 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Rpn3_C PF08375.6 EEQ35322.1 - 2.3e-24 85.5 0.3 2.3e-24 85.5 0.2 2.4 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EEQ35322.1 - 1.7e-20 73.3 0.6 6.7e-20 71.3 0.0 2.3 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EEQ35322.1 - 0.0036 17.0 0.3 0.13 11.9 0.0 3.0 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 UBN2_3 PF14244.1 EEQ35323.1 - 2.9e-07 30.1 0.1 4.7e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Tnp_P_element PF12017.3 EEQ35323.1 - 0.065 12.4 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Transposase protein DASH_Spc34 PF08657.5 EEQ35324.1 - 6.3e-59 199.7 5.7 2.2e-56 191.4 3.9 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 IncA PF04156.9 EEQ35324.1 - 0.00038 20.1 0.2 0.00049 19.7 0.1 1.2 1 0 0 1 1 1 1 IncA protein Nsp1_C PF05064.8 EEQ35324.1 - 0.019 14.5 0.6 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region Prefoldin_2 PF01920.15 EEQ35324.1 - 0.04 13.6 2.5 1.6 8.5 0.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF4140 PF13600.1 EEQ35324.1 - 0.057 13.8 1.5 6.2 7.3 0.1 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spectrin PF00435.16 EEQ35324.1 - 0.077 13.2 0.9 7.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Spectrin repeat DASH_Spc19 PF08287.6 EEQ35324.1 - 0.086 12.4 2.1 0.15 11.6 1.4 1.4 1 0 0 1 1 1 0 Spc19 CENP-Q PF13094.1 EEQ35324.1 - 0.32 11.0 5.0 14 5.7 0.4 3.2 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Uds1 PF15456.1 EEQ35324.1 - 1.2 9.0 6.5 0.22 11.5 1.2 2.0 2 1 0 2 2 2 0 Up-regulated During Septation F-box-like PF12937.2 EEQ35325.1 - 0.0021 17.7 0.0 0.0059 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ35325.1 - 0.0064 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain TFIID_20kDa PF03847.8 EEQ35326.1 - 9e-24 83.5 0.0 1.6e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CorA PF01544.13 EEQ35327.1 - 3e-15 56.0 1.4 5.3e-15 55.2 0.9 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1203 PF06718.6 EEQ35328.1 - 2.3e-25 88.6 0.0 2.7e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1203) Kdo PF06293.9 EEQ35329.1 - 3.3e-05 23.0 0.0 7.2e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEQ35329.1 - 0.0083 15.2 0.0 0.0083 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Ycf1 PF05758.7 EEQ35329.1 - 0.025 12.2 2.3 0.035 11.8 1.6 1.2 1 0 0 1 1 1 0 Ycf1 APH PF01636.18 EEQ35329.1 - 0.089 12.5 9.4 0.1 12.3 0.0 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Spore_coat_CotO PF14153.1 EEQ35329.1 - 0.4 10.0 13.7 0.78 9.1 9.5 1.4 1 0 0 1 1 1 0 Spore coat protein CotO ARGLU PF15346.1 EEQ35329.1 - 1.1 8.9 33.6 2.6 7.8 23.3 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Ctr PF04145.10 EEQ35329.1 - 3 7.8 4.7 10 6.1 3.3 1.9 1 0 0 1 1 1 0 Ctr copper transporter family Borrelia_P83 PF05262.6 EEQ35329.1 - 3.6 5.7 20.3 5.4 5.1 14.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.7 EEQ35329.1 - 5.5 6.7 14.9 9.6 6.0 10.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tom37_C PF11801.3 EEQ35329.1 - 7.9 6.3 8.8 16 5.2 6.1 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain p450 PF00067.17 EEQ35331.1 - 2e-64 217.8 0.0 2.5e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEQ35332.1 - 1.2e-70 238.3 0.0 1.5e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Prenyltrans_1 PF13243.1 EEQ35334.1 - 2.8e-18 65.9 1.1 9.9e-14 51.2 0.1 2.3 1 1 1 2 2 2 2 Prenyltransferase-like Prenyltrans_2 PF13249.1 EEQ35334.1 - 3e-15 56.6 0.1 4.6e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Prenyltransferase-like Prenyltrans PF00432.16 EEQ35334.1 - 4.3e-12 45.3 10.2 7.8e-06 25.3 0.8 3.5 3 1 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 EEQ35334.1 - 5.6e-07 29.0 0.0 0.17 10.9 0.0 3.1 1 1 1 3 3 3 3 Pectic acid lyase A2M_comp PF07678.9 EEQ35334.1 - 0.00021 20.6 0.0 0.0021 17.3 0.0 2.2 1 1 1 2 2 2 1 A-macroglobulin complement component adh_short PF00106.20 EEQ35335.1 - 1.8e-25 89.8 3.5 2.4e-25 89.3 2.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ35335.1 - 3.4e-15 56.4 0.3 4.4e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ35335.1 - 4.8e-08 32.8 2.9 9.9e-08 31.8 2.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ35335.1 - 0.018 14.4 1.2 0.036 13.4 0.9 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EEQ35335.1 - 0.076 12.6 1.2 0.14 11.7 0.9 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 EEQ35335.1 - 0.2 10.7 0.4 2 7.4 0.3 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.17 EEQ35336.1 - 2e-63 214.5 0.0 2.5e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EEQ35337.1 - 1.3e-27 96.3 0.0 3.2e-12 45.6 0.0 2.9 3 0 0 3 3 3 3 Transferase family Epimerase PF01370.16 EEQ35338.1 - 1.5e-17 63.8 0.0 2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ35338.1 - 5.5e-14 51.5 0.0 7.1e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEQ35338.1 - 2e-08 34.4 0.2 4e-08 33.4 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEQ35338.1 - 1.4e-07 30.7 0.0 9.5e-07 27.9 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EEQ35338.1 - 2e-06 27.8 0.9 3.8e-06 26.9 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EEQ35338.1 - 0.00014 20.8 0.2 0.00019 20.4 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EEQ35338.1 - 0.00033 20.3 0.3 0.00056 19.6 0.2 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EEQ35338.1 - 0.054 12.7 0.2 0.08 12.1 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.17 EEQ35339.1 - 2.8e-49 167.8 0.0 3.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EEQ35341.1 - 1.4e-06 27.3 1.2 0.0003 19.7 0.0 2.5 2 1 1 3 3 3 2 Fungal specific transcription factor domain MFS_1 PF07690.11 EEQ35342.1 - 2e-30 105.6 57.9 1.1e-28 99.9 37.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ35342.1 - 7e-06 24.8 13.1 7e-06 24.8 9.1 3.6 3 1 0 3 3 3 1 Sugar (and other) transporter Pyr_redox_3 PF13738.1 EEQ35343.1 - 2.4e-11 44.0 0.0 1e-08 35.4 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ35343.1 - 2.2e-07 29.4 0.0 0.0086 14.3 0.0 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEQ35343.1 - 0.004 16.1 0.0 0.019 13.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Filament PF00038.16 EEQ35344.1 - 1.5 8.2 37.0 0.073 12.5 8.2 2.9 2 1 0 2 2 2 0 Intermediate filament protein DUF342 PF03961.8 EEQ35344.1 - 2.2 6.6 22.2 0.21 9.9 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) eIF2A PF08662.6 EEQ35345.1 - 3.8e-84 281.2 0.1 4.5e-83 277.7 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EEQ35345.1 - 0.0016 18.2 0.1 1.3 8.9 0.1 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.1 EEQ35345.1 - 0.026 14.5 1.1 0.026 14.5 0.7 4.2 3 1 2 5 5 5 0 Carnitine deficiency-associated protein 3 NAD_binding_6 PF08030.7 EEQ35346.1 - 1.5e-33 115.9 0.0 2.4e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ35346.1 - 6e-24 83.9 0.0 2.9e-23 81.7 0.0 2.1 2 1 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EEQ35346.1 - 6.7e-13 48.8 17.5 8.2e-12 45.3 8.8 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EEQ35346.1 - 2e-05 24.6 0.0 4.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEQ35346.1 - 0.065 13.8 0.0 0.31 11.6 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Polyketide_cyc2 PF10604.4 EEQ35347.1 - 3e-05 24.2 0.1 4.1e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FAD_binding_4 PF01565.18 EEQ35348.1 - 1.2e-21 76.6 1.1 2.1e-21 75.8 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain Parvo_coat_N PF08398.5 EEQ35348.1 - 0.077 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Parvovirus coat protein VP1 p450 PF00067.17 EEQ35349.1 - 7.4e-31 107.1 0.0 1.3e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EEQ35350.1 - 7.1e-10 38.4 0.0 1.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35350.1 - 5.9e-08 32.1 0.0 1.6e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ35350.1 - 0.0029 17.3 0.1 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ35350.1 - 0.012 14.7 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ35350.1 - 0.023 13.6 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 EEQ35350.1 - 0.028 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ35350.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EEQ35351.1 - 5.8e-09 35.4 0.0 8.7e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ35351.1 - 0.022 14.4 0.1 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ35351.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Rubis-subs-bind PF09273.6 EEQ35353.1 - 3.9e-17 62.3 0.0 7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding zf-MYND PF01753.13 EEQ35353.1 - 2.7e-09 36.7 13.2 4.7e-09 35.9 9.1 1.4 1 0 0 1 1 1 1 MYND finger SET PF00856.23 EEQ35353.1 - 8.4e-08 32.6 0.0 1.3e-06 28.7 0.0 2.2 1 1 0 1 1 1 1 SET domain DUF4523 PF15023.1 EEQ35353.1 - 0.14 11.6 0.4 0.81 9.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Ribul_P_3_epim PF00834.14 EEQ35354.1 - 0.093 11.8 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family HeLo PF14479.1 EEQ35355.1 - 1.2e-42 146.0 0.1 1.5e-42 145.7 0.1 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.3 EEQ35355.1 - 1.6e-14 53.5 5.0 3.8e-14 52.3 3.5 1.6 1 0 0 1 1 1 1 Het-s 218-289 NACHT PF05729.7 EEQ35356.1 - 2.2e-29 102.2 0.1 3.7e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.27 EEQ35356.1 - 1.2e-11 44.0 1.2 1.2e-11 44.0 0.8 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat AAA_16 PF13191.1 EEQ35356.1 - 1.3e-05 25.2 0.0 5.4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ35356.1 - 2.6e-05 24.3 0.1 0.00019 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ35356.1 - 0.0025 17.5 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EEQ35356.1 - 0.003 16.6 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EEQ35356.1 - 0.0036 17.4 0.0 0.015 15.4 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 EEQ35356.1 - 0.0043 16.6 0.0 0.0084 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEQ35356.1 - 0.11 11.9 0.0 13 5.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain APH PF01636.18 EEQ35357.1 - 9.2e-09 35.3 0.0 3.9e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF2841 PF11001.3 EEQ35360.1 - 1.5e-48 163.8 0.1 2.6e-48 163.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Chorion_2 PF03964.10 EEQ35361.1 - 0.092 13.3 0.8 0.13 12.8 0.6 1.2 1 0 0 1 1 1 0 Chorion family 2 PAH PF02671.16 EEQ35364.1 - 7.6e-11 41.4 0.0 1.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat LemA PF04011.7 EEQ35365.1 - 0.021 13.9 0.2 2.2 7.3 0.0 2.1 2 0 0 2 2 2 0 LemA family p450 PF00067.17 EEQ35366.1 - 2.9e-32 111.8 0.0 2.4e-25 89.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EEQ35367.1 - 1.1e-34 119.8 0.0 1.3e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.14 EEQ35368.1 - 4.8e-53 179.6 0.0 5.6e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEQ35368.1 - 4.4e-32 111.3 0.1 5.7e-32 111.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEQ35368.1 - 2e-20 72.7 0.1 2.5e-13 49.5 0.3 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EEQ35368.1 - 1.6e-16 60.0 0.1 2e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EEQ35368.1 - 1.5e-12 47.7 0.5 2.7e-12 46.9 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EEQ35368.1 - 1.1e-11 44.1 0.1 2.5e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEQ35368.1 - 3.1e-11 43.6 0.1 4.2e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EEQ35368.1 - 1.5e-08 34.5 0.6 3.2e-08 33.4 0.4 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_3 PF03447.11 EEQ35368.1 - 0.00021 21.6 0.0 0.00063 20.1 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EEQ35368.1 - 0.0067 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EEQ35368.1 - 0.029 13.3 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 EEQ35368.1 - 0.029 13.6 0.1 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family GFO_IDH_MocA PF01408.17 EEQ35368.1 - 0.038 14.5 0.1 0.076 13.5 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PMP1_2 PF08114.6 EEQ35369.1 - 0.014 14.9 2.7 0.045 13.2 1.9 1.8 1 0 0 1 1 1 0 ATPase proteolipid family p450 PF00067.17 EEQ35370.1 - 3.7e-31 108.1 0.0 1.4e-30 106.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Pkinase PF00069.20 EEQ35372.1 - 1.5e-16 60.3 0.0 3.2e-15 55.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35372.1 - 6.7e-10 38.4 0.0 1.3e-08 34.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ35372.1 - 0.0067 16.1 0.3 0.011 15.4 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ35372.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2587 PF10759.4 EEQ35372.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) AAA PF00004.24 EEQ35373.1 - 2.9e-15 56.6 0.0 6e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ35373.1 - 0.0007 19.7 0.5 0.035 14.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ35373.1 - 0.00082 19.4 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EEQ35373.1 - 0.0009 18.9 0.0 0.0035 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EEQ35373.1 - 0.014 14.9 0.1 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Act-Frag_cataly PF09192.5 EEQ35373.1 - 0.084 11.8 0.1 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Actin-fragmin kinase, catalytic AAA_19 PF13245.1 EEQ35373.1 - 0.15 11.8 0.8 0.4 10.4 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain WD40 PF00400.27 EEQ35377.1 - 2.2e-114 369.7 9.8 6.8e-15 54.3 0.0 10.4 9 1 1 10 10 10 10 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EEQ35377.1 - 2.2e-19 69.0 0.1 0.00015 20.1 0.0 4.9 2 1 3 5 5 5 4 Cytochrome D1 heme domain TruB_C PF09142.6 EEQ35377.1 - 4.7e-17 61.3 14.4 0.012 15.2 0.0 8.3 5 2 2 8 8 8 4 tRNA Pseudouridine synthase II, C terminal PD40 PF07676.7 EEQ35377.1 - 4.6e-15 54.9 12.3 0.42 10.3 0.0 8.6 8 0 0 8 8 8 4 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EEQ35377.1 - 3.8e-14 51.6 0.0 2.7 7.3 0.0 7.6 7 0 0 7 7 7 3 Proteasome subunit A N-terminal signature VID27 PF08553.5 EEQ35377.1 - 2.8e-12 45.7 2.6 0.022 13.0 0.0 5.2 4 1 2 6 6 6 4 VID27 cytoplasmic protein GSDH PF07995.6 EEQ35377.1 - 1.8e-11 43.7 0.2 0.95 8.4 0.0 7.6 2 1 10 12 12 12 2 Glucose / Sorbosone dehydrogenase Nup160 PF11715.3 EEQ35377.1 - 3e-11 42.1 1.7 0.23 9.5 0.0 6.9 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Ank PF00023.25 EEQ35377.1 - 2.3e-10 39.7 0.0 1e-07 31.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EEQ35377.1 - 3e-09 37.0 0.0 5.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Nbas_N PF15492.1 EEQ35377.1 - 3.4e-08 32.9 3.6 3.1 6.8 0.0 5.9 1 1 4 6 6 6 4 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EEQ35377.1 - 8.2e-08 32.0 1.9 7.3e-06 25.6 0.7 3.6 2 1 1 3 3 3 1 PQQ-like domain Ank_3 PF13606.1 EEQ35377.1 - 3.7e-06 26.6 0.0 2.8e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat DUF1652 PF07865.6 EEQ35377.1 - 6.5e-06 25.6 0.0 53 3.5 0.0 7.0 8 0 0 8 8 8 0 Protein of unknown function (DUF1652) Nucleoporin_N PF08801.6 EEQ35377.1 - 1.6e-05 23.8 0.0 1.6 7.3 0.0 5.4 1 1 5 6 6 6 2 Nup133 N terminal like Ank_5 PF13857.1 EEQ35377.1 - 3.3e-05 23.9 0.0 9.8e-05 22.4 0.0 1.8 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ35377.1 - 3.5e-05 24.1 0.0 0.00036 20.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SH3_6 PF12913.2 EEQ35377.1 - 0.0011 18.1 0.2 15 4.8 0.0 5.0 6 0 0 6 6 4 0 SH3 domain of the SH3b1 type AviRa PF11599.3 EEQ35377.1 - 0.0019 17.2 0.0 19 4.1 0.0 4.9 3 2 3 6 6 6 0 RRNA methyltransferase AviRa IKI3 PF04762.7 EEQ35377.1 - 0.004 15.0 0.0 0.97 7.1 0.0 3.1 1 1 1 3 3 3 2 IKI3 family PSD5 PF07637.6 EEQ35377.1 - 0.0083 16.1 0.0 11 6.2 0.0 4.9 6 0 0 6 6 6 0 Protein of unknown function (DUF1595) Coatomer_WDAD PF04053.9 EEQ35377.1 - 0.013 14.3 0.0 2.7 6.7 0.0 3.4 2 1 3 5 5 5 0 Coatomer WD associated region Leucyl-specific PF14795.1 EEQ35377.1 - 0.019 14.8 0.3 1.6e+02 2.2 0.0 5.9 7 0 0 7 7 7 0 Leucine-tRNA synthetase-specific domain DUF4585 PF15232.1 EEQ35377.1 - 0.1 12.4 0.0 39 4.1 0.0 3.8 5 0 0 5 5 3 0 Domain of unknown function (DUF4585) DUF1258 PF06869.7 EEQ35377.1 - 0.11 11.5 0.0 3.6 6.6 0.0 3.1 4 2 1 5 5 5 0 Protein of unknown function (DUF1258) AMP-binding PF00501.23 EEQ35378.1 - 9.9e-76 254.7 0.0 1.4e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ35378.1 - 9.1e-13 48.9 0.2 3e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HeLo PF14479.1 EEQ35379.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.6 3 1 0 3 3 3 0 Prion-inhibition and propagation Acetyltransf_13 PF13880.1 EEQ35380.1 - 5.3e-28 96.5 0.0 1.3e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EEQ35380.1 - 3.6e-16 58.4 1.4 6.6e-16 57.6 1.0 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.1 EEQ35380.1 - 0.078 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acyl-CoA_dh_1 PF00441.19 EEQ35382.1 - 2.8e-25 89.1 0.6 4.2e-25 88.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ35382.1 - 2.7e-23 82.7 0.1 6.4e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ35382.1 - 4.7e-18 64.4 0.0 9.8e-18 63.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEQ35382.1 - 1.9e-09 37.8 1.2 3.1e-09 37.1 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.21 EEQ35383.1 - 1.8e-51 173.2 0.0 2.1e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ35383.1 - 8.7e-05 22.2 0.0 0.0001 22.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ35383.1 - 0.0047 16.7 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EEQ35383.1 - 0.031 13.9 0.2 0.055 13.1 0.1 1.4 1 1 0 1 1 1 0 UEV domain Glyoxalase_2 PF12681.2 EEQ35384.1 - 0.032 14.8 0.0 0.099 13.2 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Zip PF02535.17 EEQ35384.1 - 1.9 7.4 13.8 3.4 6.5 8.6 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter EMG1 PF03587.9 EEQ35385.1 - 4.8e-64 215.3 0.0 4.9e-63 212.0 0.0 1.9 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase Conotoxin PF02950.12 EEQ35386.1 - 0.012 16.4 0.7 0.019 15.7 0.5 1.5 1 0 0 1 1 1 0 Conotoxin UPF0506 PF11703.3 EEQ35386.1 - 0.05 13.5 4.4 0.086 12.8 3.1 1.4 1 0 0 1 1 1 0 UPF0506 Toxin_18 PF08087.6 EEQ35386.1 - 0.063 13.0 9.0 0.18 11.6 6.3 1.7 1 1 0 1 1 1 0 Conotoxin O-superfamily PG_binding_1 PF01471.13 EEQ35386.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain APH PF01636.18 EEQ35387.1 - 0.0066 16.2 0.2 0.0066 16.2 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 EEQ35387.1 - 0.052 13.3 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) RIO1 PF01163.17 EEQ35387.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF390 PF04094.9 EEQ35387.1 - 8.6 4.2 11.0 12 3.8 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) XPG_I PF00867.13 EEQ35388.1 - 1.1e-29 102.2 0.5 3.2e-29 100.8 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EEQ35388.1 - 8.6e-27 93.3 0.5 1.9e-26 92.2 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EEQ35388.1 - 4.5e-05 23.6 0.4 0.0002 21.5 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.6 EEQ35388.1 - 0.059 12.2 2.4 0.098 11.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF4355 PF14265.1 EEQ35388.1 - 7.9 6.4 22.1 1.3 8.9 9.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Linker_histone PF00538.14 EEQ35389.1 - 2.2e-22 78.9 0.6 2.2e-22 78.9 0.4 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF650 PF04894.7 EEQ35389.1 - 0.59 9.5 6.5 0.04 13.3 0.6 1.7 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF650) Pkinase PF00069.20 EEQ35391.1 - 1.8e-21 76.4 0.0 1.5e-11 43.9 0.0 3.6 2 1 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 EEQ35391.1 - 4.9e-06 25.7 0.0 0.076 11.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.12 EEQ35391.1 - 9.8e-05 21.5 0.0 3.7 6.5 0.0 3.8 3 1 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 EEQ35391.1 - 0.066 12.9 0.2 0.2 11.3 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIP5K PF01504.13 EEQ35392.1 - 3.5e-86 288.4 0.1 3.5e-86 288.4 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.20 EEQ35393.1 - 1.5e-12 47.2 0.0 2.3e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ35393.1 - 7.2e-07 29.1 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ35393.1 - 5.8e-06 25.5 0.0 9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EEQ35393.1 - 2.6e-05 23.4 0.0 3.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ35393.1 - 0.0055 16.0 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EEQ35393.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 EEQ35393.1 - 0.049 12.5 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EEQ35393.1 - 0.19 10.4 0.2 0.28 9.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EEQ35394.1 - 2.4e-08 34.0 0.0 6.4e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35394.1 - 0.00082 19.0 0.1 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_A_type_inc PF04508.7 EEQ35396.1 - 1.8 8.5 5.0 7.4 6.6 2.0 2.5 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat DUF524 PF04411.7 EEQ35397.1 - 0.00085 19.1 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF524) MdoG PF04349.7 EEQ35398.1 - 0.082 11.1 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG Peptidase_S64 PF08192.6 EEQ35399.1 - 0.0011 17.3 0.0 0.0016 16.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.8 EEQ35399.1 - 0.061 12.2 0.2 0.59 9.0 0.1 2.0 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 HGTP_anticodon2 PF12745.2 EEQ35400.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Pox_A_type_inc PF04508.7 EEQ35401.1 - 0.12 12.1 2.6 5.6 7.0 0.7 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF1589 PF07628.6 EEQ35402.1 - 0.029 14.2 0.3 0.056 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1589) Apc1 PF12859.2 EEQ35403.1 - 3.4e-29 101.1 0.3 3.4e-29 101.1 0.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EEQ35403.1 - 9.2e-07 28.7 9.3 0.0048 17.0 0.1 4.6 4 0 0 4 4 4 3 Proteasome/cyclosome repeat Fungal_trans_2 PF11951.3 EEQ35404.1 - 6.4e-19 67.8 0.0 1.2e-18 66.9 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EEQ35405.1 - 1.2e-26 93.3 26.4 1.2e-26 93.3 18.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily HUN PF08729.5 EEQ35406.1 - 1.6e-13 50.2 0.1 4e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 EEQ35407.1 - 7.9e-28 96.1 0.0 1.4e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EEQ35407.1 - 2e-12 46.5 3.7 3.3e-12 45.7 2.6 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal ABC2_membrane PF01061.19 EEQ35408.1 - 6.5e-54 182.2 45.4 1.2e-41 142.2 16.5 4.0 4 0 0 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.22 EEQ35408.1 - 8.7e-40 136.2 0.1 1.3e-18 67.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EEQ35408.1 - 2.9e-36 123.2 0.0 5e-28 96.7 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EEQ35408.1 - 6.6e-18 64.5 0.0 1.6e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EEQ35408.1 - 4.3e-09 36.0 0.0 1.2e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEQ35408.1 - 2.9e-07 30.4 0.2 0.0055 16.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ35408.1 - 2.6e-06 26.8 0.1 0.0015 18.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 EEQ35408.1 - 8.8e-06 25.1 0.0 0.56 9.3 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEQ35408.1 - 2.5e-05 24.3 0.1 0.00053 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EEQ35408.1 - 0.00012 22.8 0.0 0.076 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEQ35408.1 - 0.00013 21.1 0.0 0.0011 18.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EEQ35408.1 - 0.00017 21.6 0.0 0.33 10.8 0.0 3.3 3 1 0 3 3 3 1 AAA domain cobW PF02492.14 EEQ35408.1 - 0.0003 20.2 0.8 0.0022 17.4 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PDR_assoc PF08370.6 EEQ35408.1 - 0.00069 19.0 0.9 1.1 8.8 0.0 2.9 2 0 0 2 2 2 2 Plant PDR ABC transporter associated AAA_18 PF13238.1 EEQ35408.1 - 0.00075 19.8 0.0 0.02 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEQ35408.1 - 0.001 19.2 0.3 0.12 12.5 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EEQ35408.1 - 0.0013 19.1 0.0 0.11 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ35408.1 - 0.0024 17.6 0.2 2.5 7.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EEQ35408.1 - 0.0039 16.8 1.1 0.51 9.9 0.2 2.6 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 EEQ35408.1 - 0.0091 15.9 0.0 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EEQ35408.1 - 0.011 16.1 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 EEQ35408.1 - 0.015 15.5 0.1 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EEQ35408.1 - 0.026 13.9 0.3 9.1 5.6 0.0 3.3 3 1 0 3 3 3 0 AAA-like domain UPF0079 PF02367.12 EEQ35408.1 - 0.035 13.7 0.4 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EEQ35408.1 - 0.043 13.3 0.1 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EEQ35408.1 - 0.07 13.0 0.7 0.2 11.6 0.5 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEQ35408.1 - 0.14 11.6 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 EEQ35408.1 - 0.35 9.6 0.2 5.8 5.5 0.1 2.1 2 0 0 2 2 2 0 ArgK protein AAA_15 PF13175.1 EEQ35408.1 - 0.82 8.6 0.0 2.1 7.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain APH PF01636.18 EEQ35409.1 - 1.6e-14 54.2 0.0 1.1e-13 51.4 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35409.1 - 5.8e-05 22.7 0.0 9.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ35409.1 - 0.012 14.7 0.0 0.29 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35409.1 - 0.052 12.6 0.0 0.1 11.6 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase FAD_binding_3 PF01494.14 EEQ35410.1 - 9.1e-16 57.8 0.0 1.3e-14 54.0 0.0 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEQ35410.1 - 1.5e-06 27.3 0.1 0.00049 19.1 0.0 2.2 2 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EEQ35410.1 - 8.6e-06 24.6 0.0 0.001 17.8 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EEQ35410.1 - 1.2e-05 25.2 0.1 2.7e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEQ35410.1 - 6e-05 22.8 0.0 0.0072 16.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EEQ35410.1 - 0.013 14.6 0.1 1 8.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EEQ35410.1 - 0.016 15.5 0.1 0.071 13.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ35410.1 - 0.039 13.8 0.2 0.077 12.8 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EEQ35410.1 - 0.053 12.3 0.0 6.8 5.4 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.17 EEQ35410.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EEQ35410.1 - 0.15 10.8 1.4 0.25 10.1 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain Methyltransf_23 PF13489.1 EEQ35411.1 - 1.5e-15 57.2 0.0 2.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ35411.1 - 5.9e-05 23.6 0.1 0.11 13.0 0.0 2.6 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ35411.1 - 0.00011 21.8 0.0 0.051 13.1 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain DUF938 PF06080.7 EEQ35411.1 - 0.066 12.7 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_11 PF08241.7 EEQ35411.1 - 0.13 12.7 0.0 17 5.9 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain IFRD PF05004.8 EEQ35412.1 - 6.2e-31 107.6 4.3 8.2e-31 107.2 3.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Rep_4 PF05797.6 EEQ35412.1 - 0.011 14.5 0.5 0.011 14.5 0.4 2.2 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) VHS PF00790.14 EEQ35412.1 - 0.059 13.0 0.1 0.42 10.2 0.0 2.3 2 1 0 2 2 2 0 VHS domain Corona_nucleoca PF00937.13 EEQ35412.1 - 0.38 9.6 8.7 0.65 8.8 6.0 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein ORC6 PF05460.8 EEQ35412.1 - 1.1 8.2 8.9 0.093 11.8 2.2 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Pkinase PF00069.20 EEQ35413.1 - 5.7e-59 199.3 0.0 7.2e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35413.1 - 4.2e-35 121.0 0.0 5.8e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ35413.1 - 0.00081 18.4 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EEQ35413.1 - 0.063 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EEQ35413.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH2_2 PF14633.1 EEQ35414.1 - 1.2e-85 286.0 0.0 1.2e-85 286.0 0.0 3.0 3 0 0 3 3 3 1 SH2 domain DLD PF14878.1 EEQ35414.1 - 2.2e-35 121.2 5.3 2.2e-35 121.2 3.7 3.2 2 0 0 2 2 2 1 Death-like domain of SPT6 YqgF PF14639.1 EEQ35414.1 - 1e-31 109.5 0.0 3.1e-31 107.9 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 EEQ35414.1 - 1.6e-30 105.3 0.0 3.3e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 EEQ35414.1 - 2e-23 82.3 22.1 2e-23 82.3 15.3 6.1 7 1 0 7 7 7 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EEQ35414.1 - 3.5e-17 62.5 4.4 3.5e-17 62.5 3.0 3.3 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_3 PF12836.2 EEQ35414.1 - 6.3e-05 22.8 0.0 0.00035 20.4 0.0 2.4 3 0 0 3 3 3 1 Helix-hairpin-helix motif SH2 PF00017.19 EEQ35414.1 - 7.4e-05 22.4 0.0 0.00041 20.1 0.0 2.3 2 0 0 2 2 2 1 SH2 domain zf-CCCH PF00642.19 EEQ35416.1 - 1.4e-11 43.7 9.8 1.6e-06 27.6 1.7 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEQ35416.1 - 0.52 10.3 16.1 3.5 7.7 3.0 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type TBPIP PF07106.8 EEQ35417.1 - 6.2e-23 81.1 1.1 7.6e-23 80.9 0.7 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 EEQ35417.1 - 0.0046 17.3 1.0 0.026 14.9 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) IFT57 PF10498.4 EEQ35417.1 - 0.018 13.7 1.0 0.025 13.3 0.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.4 EEQ35417.1 - 0.023 14.8 1.4 0.043 13.9 0.9 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sel1 PF08238.7 EEQ35418.1 - 3e-17 62.6 18.7 9.5e-07 29.2 0.3 6.6 6 0 0 6 6 6 4 Sel1 repeat TPR_11 PF13414.1 EEQ35418.1 - 0.0062 16.1 0.2 0.0062 16.1 0.2 2.8 3 1 1 4 4 4 1 TPR repeat TPR_1 PF00515.23 EEQ35418.1 - 0.015 14.8 2.4 0.063 12.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ35418.1 - 0.95 9.5 4.2 4.3 7.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.1 EEQ35419.1 - 8.3e-56 188.5 0.0 1.7e-55 187.5 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EEQ35419.1 - 6.6e-41 139.6 0.0 1.2e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 DivIVA PF05103.8 EEQ35419.1 - 6.9 6.7 9.4 6.6 6.7 1.3 2.9 3 0 0 3 3 3 0 DivIVA protein Ribosomal_L18e PF00828.14 EEQ35420.1 - 1.2e-35 122.7 0.0 1.6e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Abhydrolase_6 PF12697.2 EEQ35421.1 - 5.3e-08 33.0 0.0 6.7e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ35421.1 - 9.6e-06 25.4 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PLDc PF00614.17 EEQ35422.1 - 2.2e-16 59.0 0.8 7.6e-08 31.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EEQ35422.1 - 1.3e-12 47.5 0.0 8.3e-08 32.0 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EEQ35422.1 - 7e-10 38.7 1.3 1.7e-09 37.4 0.3 2.1 2 0 0 2 2 2 1 PX domain AA_permease PF00324.16 EEQ35423.1 - 8.8e-61 205.6 22.9 5.1e-60 203.1 15.9 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ35423.1 - 3.9e-28 98.1 18.7 1e-27 96.7 13.2 1.4 1 1 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 EEQ35423.1 - 2.3 6.6 8.7 4.7 5.6 0.0 3.2 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) PH_7 PF15408.1 EEQ35425.1 - 0.021 14.6 0.1 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Methyltransf_31 PF13847.1 EEQ35426.1 - 7.1e-26 90.6 0.0 1.2e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ35426.1 - 2.5e-14 53.5 0.0 6.3e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ35426.1 - 1.8e-12 46.8 0.1 2.7e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EEQ35426.1 - 4.6e-11 43.2 0.1 8.2e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ35426.1 - 5.8e-10 39.1 0.0 1.5e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ35426.1 - 5.9e-09 36.1 0.0 1.3e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ35426.1 - 2.5e-06 27.2 0.1 4.6e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EEQ35426.1 - 4.3e-06 26.7 0.0 8.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ35426.1 - 1.4e-05 25.5 0.1 2.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEQ35426.1 - 4.3e-05 22.7 0.5 6.7e-05 22.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEQ35426.1 - 0.0061 15.9 0.1 0.0098 15.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EEQ35426.1 - 0.012 14.9 0.6 0.025 13.9 0.4 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_3 PF01596.12 EEQ35426.1 - 0.057 12.4 0.1 0.14 11.1 0.1 1.8 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 EEQ35426.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EEQ35426.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase bZIP_1 PF00170.16 EEQ35427.1 - 0.0054 16.6 3.9 0.0088 15.9 2.4 1.6 1 1 0 1 1 1 1 bZIP transcription factor PLRV_ORF5 PF01690.12 EEQ35427.1 - 0.041 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein bZIP_2 PF07716.10 EEQ35427.1 - 0.042 13.6 6.5 0.15 11.9 4.5 1.9 1 1 0 1 1 1 0 Basic region leucine zipper Snf7 PF03357.16 EEQ35427.1 - 0.19 11.0 1.0 0.28 10.5 0.7 1.2 1 0 0 1 1 1 0 Snf7 Peptidase_S41 PF03572.13 EEQ35428.1 - 1.5e-08 34.2 0.0 3.3e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 Anth_synt_I_N PF04715.8 EEQ35428.1 - 0.037 14.0 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Ras PF00071.17 EEQ35429.1 - 3.5e-26 91.5 0.0 5.6e-24 84.3 0.0 2.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEQ35429.1 - 0.00017 22.1 0.0 0.00042 20.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EEQ35429.1 - 0.065 12.6 0.0 0.67 9.3 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zn_clus PF00172.13 EEQ35430.1 - 4.4e-07 29.7 14.4 7.5e-07 28.9 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2043 PF09740.4 EEQ35430.1 - 0.027 14.5 2.4 0.66 10.0 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) Aldose_epim PF01263.15 EEQ35431.1 - 8.6e-49 166.2 0.0 2.4e-48 164.7 0.0 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase Glyoxalase_2 PF12681.2 EEQ35432.1 - 1.3e-09 38.6 0.0 5e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase-like domain QRPTase_C PF01729.14 EEQ35433.1 - 3.2e-45 153.6 0.6 7e-25 87.4 0.1 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EEQ35433.1 - 5e-17 61.4 0.0 1.3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain SWI-SNF_Ssr4 PF08549.5 EEQ35433.1 - 0.0097 14.2 0.4 0.011 14.0 0.3 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Mto2_bdg PF12808.2 EEQ35434.1 - 1.3e-34 118.0 33.1 3.4e-19 68.6 14.0 9.9 9 2 1 10 10 10 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Microtub_assoc PF07989.6 EEQ35434.1 - 9.1e-22 76.6 9.0 9.1e-22 76.6 6.3 7.8 8 1 1 9 9 9 1 Microtubule associated Reo_sigmaC PF04582.7 EEQ35434.1 - 0.027 13.6 31.1 0.039 13.1 1.3 5.2 2 1 1 4 4 4 0 Reovirus sigma C capsid protein PH_9 PF15410.1 EEQ35435.1 - 1.1e-19 70.7 0.1 4.3e-19 68.8 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.15 EEQ35435.1 - 1.7e-09 37.6 0.1 3.5e-07 30.0 0.0 2.6 1 1 1 2 2 2 2 Sec7 domain Lzipper-MIP1 PF14389.1 EEQ35435.1 - 0.06 13.4 0.2 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 UNC-50 PF05216.8 EEQ35437.1 - 1e-29 103.3 2.7 2.9e-29 101.9 1.9 1.7 1 0 0 1 1 1 1 UNC-50 family PetM PF08041.6 EEQ35437.1 - 0.72 9.3 2.5 2.2 7.8 1.7 1.8 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 FAD_binding_3 PF01494.14 EEQ35439.1 - 1.5e-11 43.9 0.0 3e-10 39.6 0.0 2.5 2 1 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EEQ35439.1 - 1.3e-07 31.9 0.0 8.3e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ35439.1 - 2.8e-06 27.2 0.0 5.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ35439.1 - 0.0037 16.2 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase PQQ PF01011.16 EEQ35439.1 - 0.0049 16.3 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 PQQ enzyme repeat TrkA_N PF02254.13 EEQ35439.1 - 0.048 13.6 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 EEQ35439.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EEQ35439.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EEQ35439.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.11 EEQ35441.1 - 5.4e-34 117.4 27.3 3e-33 114.9 19.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily PgaD PF13994.1 EEQ35441.1 - 0.012 15.0 0.7 0.028 13.8 0.0 2.0 2 0 0 2 2 2 0 PgaD-like protein DUF1049 PF06305.6 EEQ35441.1 - 1.3 8.5 0.0 1.3 8.5 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) PP28 PF10252.4 EEQ35442.1 - 3.7e-31 106.9 17.4 3.7e-31 106.9 12.1 3.6 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 DUF2887 PF11103.3 EEQ35442.1 - 0.45 10.0 3.7 0.73 9.4 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) MFS_1 PF07690.11 EEQ35443.1 - 8.1e-20 70.8 45.7 8.1e-20 70.8 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EEQ35444.1 - 2.7e-29 102.1 0.0 1.3e-27 96.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35444.1 - 1.1e-09 37.8 0.0 3.7e-07 29.4 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase RicinB_lectin_2 PF14200.1 EEQ35447.1 - 0.0031 17.8 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Gyro_capsid PF04162.7 EEQ35447.1 - 0.1 10.8 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Cupredoxin_1 PF13473.1 EEQ35447.1 - 0.13 12.2 0.0 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 Cupredoxin-like domain Acetyltransf_1 PF00583.19 EEQ35448.1 - 4.3e-08 33.0 0.0 5.6e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ35448.1 - 0.065 13.4 0.0 0.44 10.7 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ35448.1 - 0.079 12.7 0.1 16 5.3 0.0 2.4 1 1 1 2 2 2 0 FR47-like protein Glyco_transf_20 PF00982.16 EEQ35449.1 - 7.8e-149 496.1 0.0 2.4e-148 494.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEQ35449.1 - 4.4e-87 290.8 0.0 1.1e-86 289.5 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase HAD PF12710.2 EEQ35449.1 - 0.075 13.1 0.1 0.29 11.2 0.1 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase APH PF01636.18 EEQ35450.1 - 1.6e-14 54.2 0.0 2.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35450.1 - 3.6e-06 26.6 0.0 9e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ35450.1 - 0.00017 20.8 0.0 0.27 10.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.9 EEQ35450.1 - 0.0051 15.9 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EEQ35450.1 - 0.056 12.5 0.1 0.27 10.2 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase Glyco_hydro_56 PF01630.13 EEQ35450.1 - 0.18 10.4 1.7 3.6 6.1 0.0 2.4 2 1 1 3 3 3 0 Hyaluronidase LETM1 PF07766.8 EEQ35452.1 - 1.4e-06 27.5 2.9 0.00056 19.0 2.0 2.3 1 1 0 1 1 1 1 LETM1-like protein ZZ PF00569.12 EEQ35453.1 - 1.9e-16 59.2 39.8 1.9e-06 27.3 5.5 3.4 3 0 0 3 3 3 3 Zinc finger, ZZ type Btz PF09405.5 EEQ35454.1 - 2.2e-17 63.2 0.6 2.2e-17 63.2 0.4 2.1 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.17 EEQ35456.1 - 1.3e-24 85.5 0.1 1.3e-14 53.5 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ35456.1 - 4.5e-24 84.2 0.0 2.7e-13 49.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ35456.1 - 2.5e-07 30.4 0.1 0.0047 16.7 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ino80_Iec3 PF14612.1 EEQ35457.1 - 8.8e-81 271.3 0.3 1.3e-80 270.7 0.2 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Sec34 PF04136.10 EEQ35457.1 - 0.012 15.3 0.2 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Sec34-like family Protocadherin PF08374.6 EEQ35457.1 - 0.03 13.9 1.2 0.06 12.9 0.9 1.5 1 0 0 1 1 1 0 Protocadherin IF2_N PF04760.10 EEQ35457.1 - 0.045 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region FAD_binding_4 PF01565.18 EEQ35458.1 - 1.7e-16 59.9 1.2 4e-16 58.7 0.9 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ35458.1 - 4.2e-08 32.9 0.1 4.2e-08 32.9 0.0 2.3 3 0 0 3 3 3 1 Berberine and berberine like Cytokin-bind PF09265.5 EEQ35458.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding MFS_1 PF07690.11 EEQ35459.1 - 5.8e-07 28.5 14.0 5.8e-07 28.5 9.7 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Dynamin_N PF00350.18 EEQ35460.1 - 5.2e-33 114.2 0.1 1e-32 113.2 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ35460.1 - 1.3e-14 53.6 0.0 8.3e-14 51.0 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EEQ35460.1 - 2.6e-05 24.1 0.0 0.00015 21.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ35460.1 - 0.0036 17.7 0.0 0.011 16.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EEQ35460.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EEQ35460.1 - 0.16 11.2 0.3 14 4.9 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B ECR1_N PF14382.1 EEQ35461.1 - 2.2e-09 36.4 0.0 4.8e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EEQ35461.1 - 0.00091 19.1 0.1 0.015 15.2 0.1 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Oxysterol_BP PF01237.13 EEQ35462.1 - 1.6e-118 395.2 0.3 2.8e-118 394.4 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EEQ35462.1 - 4.7e-38 129.1 1.1 7.2e-38 128.5 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 EEQ35462.1 - 0.13 12.5 7.7 0.028 14.6 1.7 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Plus-3 PF03126.13 EEQ35463.1 - 6.5e-30 103.3 0.0 1.4e-28 99.0 0.0 2.7 3 0 0 3 3 3 1 Plus-3 domain COQ7 PF03232.8 EEQ35464.1 - 1.2e-59 200.6 0.1 1.6e-59 200.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EEQ35464.1 - 0.0019 18.5 0.0 0.0047 17.2 0.0 1.8 1 1 0 1 1 1 1 Rubrerythrin LMWPc PF01451.16 EEQ35465.1 - 4e-36 124.3 0.0 4.5e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.12 EEQ35466.1 - 8.4e-81 269.5 0.0 1.2e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EEQ35466.1 - 2e-30 104.2 0.0 3.8e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEQ35466.1 - 4.2e-21 74.9 0.7 5.1e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EEQ35466.1 - 5.5e-11 42.5 0.1 5.5e-11 42.5 0.1 2.7 2 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ35466.1 - 2.3e-08 34.1 0.0 1.6e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Lipase_GDSL_2 PF13472.1 EEQ35467.1 - 3.8e-18 66.2 1.1 1.7e-17 64.1 0.7 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family UPF0546 PF10639.4 EEQ35468.1 - 4.9e-36 122.9 2.5 4.4e-35 119.9 1.8 2.1 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EEQ35468.1 - 0.011 15.7 4.6 0.011 15.7 3.2 2.2 3 0 0 3 3 3 0 EamA-like transporter family EmrE PF13536.1 EEQ35468.1 - 4 7.6 14.5 0.041 14.0 3.6 2.4 3 1 0 3 3 3 0 Multidrug resistance efflux transporter Pkinase_Tyr PF07714.12 EEQ35469.1 - 3.9e-06 26.1 0.0 0.053 12.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EEQ35470.1 - 6.3e-10 38.6 0.0 1.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35470.1 - 0.0058 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ35470.1 - 0.016 14.5 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EEQ35470.1 - 0.14 11.9 0.1 0.75 9.4 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Sulfate_transp PF00916.15 EEQ35471.1 - 0.00012 21.1 5.4 0.00012 21.1 3.8 2.8 2 1 1 3 3 3 1 Sulfate transporter family TFIIA PF03153.8 EEQ35472.1 - 0.34 10.7 4.2 0.36 10.6 2.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EEQ35472.1 - 1.5 8.1 19.0 1.8 7.8 13.2 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EEQ35472.1 - 1.8 6.6 17.9 1.9 6.5 12.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PhyH PF05721.8 EEQ35473.1 - 7.5e-45 153.5 0.0 9.8e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EEQ35473.1 - 0.044 14.0 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase UTP15_C PF09384.5 EEQ35474.1 - 1.3e-49 167.7 0.5 3.3e-49 166.3 0.0 1.8 1 1 1 2 2 2 1 UTP15 C terminal WD40 PF00400.27 EEQ35474.1 - 4.5e-23 80.2 6.7 2.7e-07 30.2 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EEQ35474.1 - 2.7e-06 27.0 0.8 4.6e-05 22.9 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain C2 PF00168.25 EEQ35475.1 - 4.1e-12 45.7 0.0 8e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain AAA_12 PF13087.1 EEQ35476.1 - 4.2e-29 101.3 0.0 7.2e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ35476.1 - 1.8e-18 66.9 0.0 1.9e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EEQ35476.1 - 1.3e-08 34.4 0.0 4.1e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 EEQ35476.1 - 0.00026 20.4 0.0 0.00085 18.7 0.0 1.8 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EEQ35476.1 - 0.0012 18.4 0.0 0.0035 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EEQ35476.1 - 0.0079 15.7 0.0 0.56 9.6 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EEQ35476.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C PF13361.1 EEQ35476.1 - 0.12 11.7 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Fungal_trans PF04082.13 EEQ35477.1 - 1.5e-10 40.4 0.5 2.1e-10 39.9 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ35477.1 - 1.7e-10 40.5 10.4 3.1e-10 39.8 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_2 PF13519.1 EEQ35478.1 - 0.00015 21.8 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EEQ35478.1 - 0.033 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain zf-Di19 PF05605.7 EEQ35478.1 - 0.21 11.7 7.1 0.6 10.2 0.1 3.9 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF2786 PF10979.3 EEQ35478.1 - 0.24 11.1 3.7 1.8 8.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) zf-C2H2_2 PF12756.2 EEQ35478.1 - 0.41 10.7 7.3 6.4 6.9 0.0 4.0 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) OTU PF02338.14 EEQ35480.1 - 3.1e-12 47.1 0.0 5.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 EEQ35480.1 - 0.0065 16.7 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Peptidase_C65 PF10275.4 EEQ35480.1 - 0.081 12.2 0.0 0.3 10.4 0.0 1.7 1 1 1 2 2 2 0 Peptidase C65 Otubain Bromodomain PF00439.20 EEQ35481.1 - 1e-34 118.3 5.3 1.2e-18 66.8 0.5 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EEQ35481.1 - 3.8e-15 55.6 0.3 7.7e-15 54.6 0.2 1.5 1 0 0 1 1 1 1 BAH domain MRC1 PF09444.5 EEQ35482.1 - 1.5e-38 132.3 19.1 1.5e-38 132.3 13.3 5.7 4 2 1 5 5 5 1 MRC1-like domain Cwf_Cwc_15 PF04889.7 EEQ35483.1 - 1.8 8.1 4.4 2.8 7.5 3.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Hydrolase_like PF13242.1 EEQ35484.1 - 9.8e-07 28.4 0.0 2.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EEQ35484.1 - 9.5e-05 22.6 1.7 0.012 15.8 0.1 2.9 3 2 0 3 3 3 2 Haloacid dehalogenase-like hydrolase PqqD PF05402.7 EEQ35484.1 - 0.088 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) MIF4G PF02854.14 EEQ35485.1 - 4e-23 81.9 3.3 1.5e-22 80.0 1.6 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EEQ35485.1 - 3.2e-17 62.2 0.1 1.2e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.10 EEQ35486.1 - 6.3e-25 86.9 0.0 8.7e-25 86.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Inp1 PF12634.2 EEQ35487.1 - 6.2e-25 87.5 0.0 2.5e-24 85.5 0.0 2.0 1 1 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 EEQ35488.1 - 0.0081 15.6 19.0 0.018 14.4 4.1 3.4 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Sugar_tr PF00083.19 EEQ35490.1 - 1.8e-38 132.3 22.7 8.7e-26 90.4 4.1 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ35490.1 - 1.3e-22 80.0 20.3 2.7e-20 72.4 12.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4237 PF14021.1 EEQ35495.1 - 1.4e-32 111.8 0.0 2.2e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) FmdA_AmdA PF03069.10 EEQ35496.1 - 2.4e-15 56.1 0.1 2.1e-14 53.0 0.1 1.9 2 0 0 2 2 2 2 Acetamidase/Formamidase family Pro_isomerase PF00160.16 EEQ35497.1 - 8e-39 133.3 0.3 1.4e-38 132.5 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EEQ35497.1 - 1.4e-07 31.0 11.8 0.0012 18.4 0.4 2.5 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEQ35497.1 - 4.7e-05 22.8 2.0 4.7e-05 22.8 1.4 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ35497.1 - 5e-05 22.8 4.0 5e-05 22.8 2.8 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ35497.1 - 0.017 14.9 2.8 0.018 14.8 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ35497.1 - 0.041 13.6 1.3 0.041 13.6 0.9 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ35497.1 - 0.26 11.2 12.2 0.94 9.4 5.6 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ35497.1 - 0.27 11.9 16.0 0.2 12.3 7.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ35497.1 - 0.5 10.7 8.5 7.4 6.9 2.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ35497.1 - 0.52 11.0 11.4 0.19 12.4 2.5 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.11 EEQ35498.1 - 4.8e-46 156.3 0.0 5.4e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF29 PF01724.11 EEQ35498.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF29 Not3 PF04065.10 EEQ35499.1 - 4.7e-96 320.5 16.9 7.2e-96 319.9 11.7 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EEQ35499.1 - 4.5e-36 123.6 9.0 1e-35 122.4 6.2 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Poty_PP PF08440.5 EEQ35499.1 - 0.0028 16.7 1.3 0.0055 15.8 0.9 1.4 1 0 0 1 1 1 1 Potyviridae polyprotein DUF2373 PF10180.4 EEQ35499.1 - 0.019 14.4 3.8 0.041 13.4 2.6 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 EEQ35499.1 - 0.049 13.5 3.9 0.1 12.5 0.1 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.1 EEQ35499.1 - 2.3 8.5 8.5 4.5 7.6 0.7 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin PF00804.20 EEQ35499.1 - 8.6 6.5 14.5 3.2 7.9 3.0 2.8 2 0 0 2 2 2 0 Syntaxin zf-C2H2_4 PF13894.1 EEQ35500.1 - 7.8e-06 25.8 6.6 0.019 15.2 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ35500.1 - 0.00022 21.3 6.9 0.043 14.1 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type APH PF01636.18 EEQ35501.1 - 1.8e-13 50.7 0.0 5.3e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ35502.1 - 0.00088 18.4 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EEQ35504.1 - 1.3e-12 47.4 0.0 3.9e-11 42.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35504.1 - 2.5e-06 26.7 0.0 7.4e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ35504.1 - 0.00034 19.7 0.0 0.00062 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ35504.1 - 0.15 11.7 0.2 0.39 10.4 0.1 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family DNA_binding_1 PF01035.15 EEQ35506.1 - 4e-24 84.1 0.0 6.1e-24 83.5 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Rubella_Capsid PF05750.6 EEQ35506.1 - 0.0038 16.6 0.8 0.0056 16.1 0.0 1.6 2 0 0 2 2 2 1 Rubella capsid protein DUF3439 PF11921.3 EEQ35506.1 - 0.2 11.4 4.7 0.29 10.8 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sugar_tr PF00083.19 EEQ35507.1 - 4.6e-48 163.9 7.2 5.6e-48 163.6 5.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ35507.1 - 8.4e-19 67.4 10.7 9.5e-19 67.3 7.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ35507.1 - 5.5e-05 21.5 3.9 8.5e-05 20.9 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EEQ35507.1 - 0.0025 16.2 1.7 0.0025 16.2 1.2 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein Gly-zipper_YMGG PF13441.1 EEQ35507.1 - 0.007 15.8 6.7 0.015 14.7 4.6 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 EEQ35507.1 - 0.0089 15.6 9.1 0.023 14.3 6.3 1.8 1 1 0 1 1 1 1 Glycine zipper 2TM domain OATP PF03137.15 EEQ35507.1 - 0.064 11.2 0.0 0.064 11.2 0.0 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EEQ35507.1 - 0.074 13.0 1.5 0.21 11.6 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1228) Gly-zipper_OmpA PF13436.1 EEQ35507.1 - 0.14 11.8 2.8 0.27 10.9 1.9 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Ub-Mut7C PF14451.1 EEQ35507.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Mut7-C ubiquitin Gly-zipper_Omp PF13488.1 EEQ35507.1 - 3 7.5 9.7 7.9 6.1 6.6 1.7 1 1 0 1 1 1 0 Glycine zipper Pyr_redox_dim PF02852.17 EEQ35508.1 - 4.9e-39 132.7 0.1 1.2e-38 131.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EEQ35508.1 - 2.4e-16 60.2 5.1 7.8e-10 38.9 1.7 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ35508.1 - 5.9e-14 52.2 1.7 2e-13 50.5 1.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEQ35508.1 - 0.00052 19.2 4.1 0.0021 17.1 1.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ35508.1 - 0.00068 18.5 4.9 0.00078 18.4 2.5 1.7 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EEQ35508.1 - 0.0048 15.4 1.9 0.0099 14.3 0.3 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EEQ35508.1 - 0.0052 15.6 3.2 0.0089 14.9 2.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 EEQ35508.1 - 0.0083 15.0 5.1 0.57 9.0 1.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EEQ35508.1 - 0.027 13.5 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase THF_DHG_CYH_C PF02882.14 EEQ35508.1 - 0.038 13.0 0.1 0.093 11.8 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain K_oxygenase PF13434.1 EEQ35508.1 - 0.068 12.0 0.1 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EEQ35508.1 - 0.08 12.0 1.5 0.13 11.2 1.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EEQ35508.1 - 0.087 12.8 0.8 0.21 11.6 0.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF1106 PF06523.6 EEQ35508.1 - 0.15 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) PGM_PMM_I PF02878.11 EEQ35510.1 - 1e-28 99.5 0.0 1.8e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EEQ35510.1 - 2.2e-23 82.5 0.0 5.5e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EEQ35510.1 - 1.9e-15 56.8 0.0 3.6e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EEQ35510.1 - 3.8e-08 33.2 0.0 9.5e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FA_desaturase PF00487.19 EEQ35511.1 - 4.7e-37 127.8 24.9 6.9e-37 127.2 17.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EEQ35511.1 - 2.3e-12 46.5 0.0 5e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CUE PF02845.11 EEQ35512.1 - 2e-10 39.9 0.1 4.5e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.17 EEQ35513.1 - 2.3e-28 97.8 0.6 2.9e-28 97.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH PF00642.19 EEQ35514.1 - 9.7e-07 28.3 2.6 1.8e-06 27.5 1.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEQ35514.1 - 0.21 11.6 2.4 0.51 10.4 1.7 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type ELYS PF13934.1 EEQ35515.1 - 5.3e-78 261.8 0.0 7.1e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly Pox_I3 PF04661.7 EEQ35515.1 - 0.013 14.2 0.0 0.26 10.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus I3 ssDNA-binding protein SMC_N PF02463.14 EEQ35516.1 - 2.9e-67 226.1 37.0 1.1e-66 224.2 25.6 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEQ35516.1 - 1.6e-28 99.0 0.3 8.9e-28 96.6 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEQ35516.1 - 1.3e-10 41.7 12.7 4e-05 23.7 0.9 3.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ35516.1 - 0.00025 20.4 0.0 0.00053 19.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EEQ35516.1 - 0.00059 19.1 2.3 0.00059 19.1 1.6 5.3 3 2 4 7 7 7 3 Reovirus sigma C capsid protein Filament PF00038.16 EEQ35516.1 - 0.0015 18.0 13.1 0.0015 18.0 9.1 5.2 3 2 1 4 4 4 2 Intermediate filament protein Bacillus_HBL PF05791.6 EEQ35516.1 - 0.0062 15.9 1.1 0.0062 15.9 0.8 6.9 3 2 2 6 6 6 1 Bacillus haemolytic enterotoxin (HBL) CRCB PF02537.10 EEQ35516.1 - 0.26 11.1 0.0 0.48 10.3 0.0 1.3 1 0 0 1 1 1 0 CrcB-like protein AAA_13 PF13166.1 EEQ35516.1 - 1.8 6.8 110.3 0.15 10.5 3.3 6.4 3 2 2 6 6 6 0 AAA domain IncA PF04156.9 EEQ35516.1 - 8.6 5.9 121.2 0.15 11.5 5.4 8.1 2 2 5 7 7 7 0 IncA protein Fungal_trans PF04082.13 EEQ35517.1 - 2.3e-12 46.3 0.7 4.7e-12 45.3 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ35517.1 - 3.5e-08 33.2 5.2 7e-08 32.2 3.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.7 EEQ35518.1 - 4.3e-46 157.7 0.0 5.6e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Ribonuc_L-PSP PF01042.16 EEQ35519.1 - 7.3e-10 38.6 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.27 EEQ35520.1 - 3.6e-08 32.9 5.4 0.00024 20.8 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat MMS1_N PF10433.4 EEQ35520.1 - 0.011 13.9 0.0 0.041 12.0 0.0 1.9 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PmbA_TldD PF01523.11 EEQ35520.1 - 0.49 9.6 6.4 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative modulator of DNA gyrase DUF1777 PF08648.7 EEQ35520.1 - 8.6 6.0 12.4 19 4.9 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RNA_pol_N PF01194.12 EEQ35521.1 - 2.7e-30 104.1 1.7 3.1e-30 103.9 1.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EEQ35521.1 - 0.13 12.3 1.6 0.31 11.1 1.1 1.6 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Fer4_13 PF13370.1 EEQ35522.1 - 0.91 9.9 3.6 8.3 6.8 0.0 3.7 3 2 1 4 4 4 0 4Fe-4S single cluster domain Sugar_tr PF00083.19 EEQ35523.1 - 8.5e-102 341.0 28.3 9.7e-102 340.8 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ35523.1 - 2.6e-25 88.9 34.6 2.1e-16 59.6 6.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EEQ35523.1 - 4.4 5.2 15.8 0.27 9.2 2.1 3.7 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DIOX_N PF14226.1 EEQ35524.1 - 2.5e-34 118.2 0.0 2.6e-32 111.7 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEQ35524.1 - 1.9e-14 53.7 0.0 4.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EEQ35525.1 - 3.9e-37 127.7 47.0 3.9e-37 127.7 32.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ35525.1 - 3e-05 22.7 30.4 0.00031 19.4 8.6 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter DUF2254 PF10011.4 EEQ35525.1 - 0.0017 16.8 0.0 0.004 15.6 0.0 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) DNA_primase_S PF01896.14 EEQ35526.1 - 2.8e-55 186.1 0.1 6.6e-55 184.9 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit YL1 PF05764.8 EEQ35526.1 - 0.91 9.0 12.7 1.6 8.2 8.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein MAM33 PF02330.11 EEQ35527.1 - 4.3e-32 111.5 0.4 5.3e-32 111.2 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF2962 PF11176.3 EEQ35529.1 - 4.8e-47 159.3 4.8 5.5e-47 159.1 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF4510 PF14971.1 EEQ35529.1 - 0.46 10.6 6.4 4.8 7.3 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) XPG_I PF00867.13 EEQ35530.1 - 5.4e-24 84.0 0.0 1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EEQ35530.1 - 2.2e-21 75.9 0.0 2.4e-20 72.6 0.0 2.4 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 EEQ35530.1 - 0.0071 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.12 EEQ35530.1 - 0.035 14.0 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Fig1 PF12351.3 EEQ35532.1 - 3.4e-57 193.2 4.4 3.4e-57 193.2 3.1 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EEQ35532.1 - 2.6e-08 33.6 7.4 8.7e-08 31.9 5.1 1.8 1 1 0 1 1 1 1 SUR7/PalI family FmdA_AmdA PF03069.10 EEQ35532.1 - 0.088 11.4 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Acetamidase/Formamidase family DUF898 PF05987.8 EEQ35532.1 - 0.31 9.8 12.6 0.022 13.6 4.7 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 EEQ35532.1 - 1.1 9.4 11.5 25 5.1 4.9 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) MLTD_N PF06474.7 EEQ35532.1 - 1.2 9.4 7.5 0.58 10.3 2.6 2.4 2 0 0 2 2 2 0 MltD lipid attachment motif DUF2410 PF10307.4 EEQ35533.1 - 1.3e-79 266.1 0.0 2.5e-79 265.2 0.0 1.4 2 0 0 2 2 2 1 Hypothetical protein (DUF2410) zf-RING_2 PF13639.1 EEQ35534.1 - 2.7e-08 33.5 3.6 4.7e-08 32.7 2.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ35534.1 - 5.6e-07 29.1 0.8 9.2e-07 28.4 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ35534.1 - 2.1e-06 27.6 3.9 3.8e-06 26.8 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ35534.1 - 1.3e-05 24.7 2.9 2.4e-05 23.8 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ35534.1 - 0.0018 18.3 3.9 0.0065 16.5 2.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEQ35534.1 - 0.24 11.1 1.7 0.42 10.3 1.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-MIZ PF02891.15 EEQ35534.1 - 0.25 10.9 2.8 0.48 9.9 1.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Drc1-Sld2 PF11719.3 EEQ35535.1 - 2.3e-82 277.3 16.3 2.7e-82 277.1 11.3 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein 2-oxoacid_dh PF00198.18 EEQ35536.1 - 3.3e-52 177.0 0.7 4.5e-51 173.3 0.5 2.3 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEQ35536.1 - 4.3e-16 58.3 0.8 8.5e-16 57.3 0.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EEQ35536.1 - 0.0055 15.8 4.0 0.054 12.6 0.7 2.4 1 1 2 3 3 3 2 HlyD family secretion protein RR_TM4-6 PF06459.7 EEQ35536.1 - 5.3 6.8 12.1 7.6 6.3 8.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Complex1_LYR PF05347.10 EEQ35537.1 - 9.6e-07 28.5 0.3 1.4e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ35537.1 - 0.00022 21.3 0.7 0.00035 20.7 0.5 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 EEQ35538.1 - 2.8e-24 85.0 0.0 3.5e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEQ35538.1 - 3.4e-05 23.8 0.0 4.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4336 PF14234.1 EEQ35538.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Histone PF00125.19 EEQ35539.1 - 4.3e-20 71.6 0.3 6.4e-20 71.0 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEQ35539.1 - 9.8e-05 22.3 1.7 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EEQ35539.1 - 0.003 17.8 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EEQ35539.1 - 0.015 14.8 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EEQ35539.1 - 0.039 14.4 0.4 0.054 14.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) ImcF-related_N PF14331.1 EEQ35539.1 - 0.074 11.9 0.1 0.092 11.6 0.1 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain Peptidase_C54 PF03416.14 EEQ35540.1 - 2.7e-94 315.4 0.0 4.7e-94 314.6 0.0 1.4 2 0 0 2 2 2 1 Peptidase family C54 Stathmin PF00836.14 EEQ35540.1 - 0.15 11.6 1.4 0.25 10.9 0.9 1.2 1 0 0 1 1 1 0 Stathmin family Herpes_TK PF00693.13 EEQ35540.1 - 0.18 10.9 0.0 0.74 8.9 0.0 1.8 2 0 0 2 2 2 0 Thymidine kinase from herpesvirus R3H PF01424.17 EEQ35541.1 - 3.6e-13 48.9 0.0 7.4e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EEQ35541.1 - 4e-09 36.1 0.3 8.6e-09 35.0 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEQ35541.1 - 0.029 14.2 0.3 0.029 14.2 0.2 2.4 3 0 0 3 3 3 0 DExH-box splicing factor binding site DnaJ PF00226.26 EEQ35542.1 - 5.7e-26 90.0 0.5 5.7e-26 90.0 0.3 2.7 2 1 0 2 2 2 1 DnaJ domain zf-met PF12874.2 EEQ35542.1 - 1.5e-11 44.0 7.7 3e-09 36.7 1.7 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ35542.1 - 5e-11 42.4 10.5 1.3e-09 37.8 3.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEQ35542.1 - 1.2e-08 34.9 7.7 0.0006 19.8 1.4 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EEQ35542.1 - 1.6e-07 31.2 7.5 0.0015 18.7 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ35542.1 - 6.5e-05 22.9 4.7 0.042 14.1 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ35542.1 - 0.00052 19.8 8.3 0.049 13.5 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.17 EEQ35542.1 - 0.024 14.6 4.1 0.84 9.7 0.5 2.4 2 0 0 2 2 2 0 LIM domain zf-BED PF02892.10 EEQ35542.1 - 0.028 14.1 0.1 3 7.6 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 EEQ35542.1 - 0.088 13.1 1.9 2.1 8.8 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.7 EEQ35542.1 - 1.3 9.2 6.6 5.1 7.2 0.0 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding YccV-like PF08755.6 EEQ35544.1 - 8.2e-26 89.8 0.2 1.6e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EEQ35544.1 - 6e-13 48.5 0.0 1.4e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EEQ35544.1 - 8e-06 25.4 0.0 1.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ35544.1 - 0.00086 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain SPX PF03105.14 EEQ35545.1 - 1.3e-33 117.0 0.0 1.8e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EEQ35545.1 - 2.2e-06 27.4 11.1 2.2e-06 27.4 7.7 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EEQ35545.1 - 1.1e-05 24.9 9.8 1.1e-05 24.9 6.8 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ35545.1 - 4.7e-05 22.9 11.9 4.7e-05 22.9 8.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ35545.1 - 4.7e-05 23.1 12.0 4.7e-05 23.1 8.3 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ35545.1 - 7.2e-05 22.4 10.5 7.2e-05 22.4 7.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ35545.1 - 0.00014 21.8 12.9 0.00014 21.8 9.0 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TerY-C PF15616.1 EEQ35545.1 - 0.0015 18.4 1.1 0.003 17.4 0.7 1.5 1 0 0 1 1 1 1 TerY-C metal binding domain zf-Apc11 PF12861.2 EEQ35545.1 - 0.0044 16.8 3.4 0.011 15.5 1.9 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEQ35545.1 - 0.011 15.3 3.2 0.011 15.3 2.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EEQ35545.1 - 0.048 13.7 4.7 0.16 12.0 3.3 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EEQ35545.1 - 0.1 12.3 9.6 0.29 10.8 6.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EEQ35545.1 - 0.17 11.4 4.7 0.43 10.1 3.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 EEQ35545.1 - 0.33 10.4 8.8 0.67 9.4 3.2 2.3 1 1 1 2 2 2 0 P-11 zinc finger DUF3347 PF11827.3 EEQ35545.1 - 1.9 8.4 6.4 0.24 11.3 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Peptidase_C12 PF01088.16 EEQ35546.1 - 2.4e-60 203.3 0.0 4.3e-60 202.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 I-set PF07679.11 EEQ35547.1 - 0.00014 21.6 0.1 0.025 14.4 0.0 3.9 4 1 0 4 4 4 1 Immunoglobulin I-set domain DUF1918 PF08940.6 EEQ35547.1 - 0.0066 15.7 0.8 20 4.6 0.0 4.5 5 0 0 5 5 5 2 Domain of unknown function (DUF1918) Nrap PF03813.9 EEQ35548.1 - 1.2e-302 1006.1 0.0 1.5e-302 1005.9 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Cys_Met_Meta_PP PF01053.15 EEQ35549.1 - 2.6e-34 118.1 0.0 3.4e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MIP-T3 PF10243.4 EEQ35550.1 - 3.7 5.9 9.2 5.5 5.3 6.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MRP-L20 PF12824.2 EEQ35551.1 - 9.5e-59 198.0 4.0 1.1e-58 197.8 2.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EEQ35551.1 - 0.026 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Neugrin Peptidase_M20 PF01546.23 EEQ35552.1 - 1e-28 100.1 0.0 2.1e-28 99.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEQ35552.1 - 6.7e-13 48.3 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain CobS_N PF12556.3 EEQ35552.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal PRELI PF04707.9 EEQ35553.1 - 7.8e-25 87.2 0.1 1.5e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family Cyt_c_ox_IV PF12270.3 EEQ35553.1 - 0.028 14.1 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV His_Phos_1 PF00300.17 EEQ35554.1 - 9.2e-16 58.3 0.0 1.1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.20 EEQ35555.1 - 6.1e-73 245.1 0.0 8.5e-73 244.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35555.1 - 3e-37 128.1 0.0 4.2e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EEQ35555.1 - 2.8e-10 40.1 0.0 6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EEQ35555.1 - 3e-06 26.4 0.0 9e-06 24.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EEQ35555.1 - 7.7e-05 22.1 0.2 0.00016 21.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EEQ35555.1 - 0.0016 17.0 0.1 0.0024 16.5 0.1 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EEQ35555.1 - 0.032 13.9 2.6 0.058 13.1 0.0 2.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family Paramyxo_P PF01806.12 EEQ35555.1 - 0.059 12.6 0.7 0.098 11.8 0.5 1.2 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region Seadorna_VP7 PF07387.6 EEQ35555.1 - 0.11 11.2 0.5 0.18 10.6 0.4 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MARVEL PF01284.18 EEQ35556.1 - 1.5e-24 86.4 10.4 1.9e-24 86.1 7.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain Fig1 PF12351.3 EEQ35556.1 - 0.26 11.1 5.5 0.28 11.0 3.1 1.6 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Nop14 PF04147.7 EEQ35558.1 - 0.78 7.5 28.8 0.9 7.3 20.0 1.1 1 0 0 1 1 1 0 Nop14-like family PRP21_like_P PF12230.3 EEQ35558.1 - 3.4 7.1 15.8 1.4 8.3 2.7 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein CENP-T PF15511.1 EEQ35558.1 - 4.3 6.4 17.3 5.5 6.1 12.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T His_Phos_1 PF00300.17 EEQ35560.1 - 7e-18 65.2 0.0 9.7e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M28 PF04389.12 EEQ35561.1 - 9.4e-28 97.1 0.1 1.5e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 SoxG PF04268.7 EEQ35561.1 - 0.029 14.2 0.1 0.35 10.7 0.1 2.2 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family Peptidase_M20 PF01546.23 EEQ35561.1 - 0.12 11.8 1.3 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 FG-GAP_2 PF14312.1 EEQ35561.1 - 0.97 9.4 3.6 6.6 6.8 0.0 3.0 3 0 0 3 3 3 0 FG-GAP repeat RRM_1 PF00076.17 EEQ35563.1 - 1.4e-52 175.1 0.1 1.4e-20 72.7 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ35563.1 - 4.1e-45 151.6 0.0 2.7e-16 59.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ35563.1 - 1.1e-24 86.0 0.0 8.8e-08 31.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ35563.1 - 2e-07 30.6 0.0 1.9e-05 24.3 0.0 3.6 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EEQ35563.1 - 0.011 15.5 0.0 0.072 12.8 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.1 EEQ35563.1 - 0.048 14.3 2.3 3.5 8.5 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Lsm_interact PF05391.6 EEQ35563.1 - 0.12 11.8 0.3 0.29 10.6 0.2 1.7 1 0 0 1 1 1 0 Lsm interaction motif HAP PF03866.8 EEQ35565.1 - 0.26 11.0 8.1 0.048 13.4 1.0 3.0 3 1 0 3 3 3 0 Hydrophobic abundant protein (HAP) DEAD PF00270.24 EEQ35566.1 - 3.3e-44 150.3 0.0 7.1e-44 149.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEQ35566.1 - 3.6e-22 77.6 0.2 7.5e-22 76.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EEQ35566.1 - 3.5e-21 74.8 0.0 8.4e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEQ35566.1 - 0.27 11.3 1.1 1.2 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain Ribosomal_L22 PF00237.14 EEQ35567.1 - 9.7e-16 57.6 0.1 1.7e-07 31.1 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e Mrr_N PF14338.1 EEQ35567.1 - 0.027 14.5 0.1 0.072 13.1 0.1 1.6 1 0 0 1 1 1 0 Mrr N-terminal domain GspH PF12019.3 EEQ35567.1 - 0.061 13.4 0.1 8.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Type II transport protein GspH gpUL132 PF11359.3 EEQ35568.1 - 0.008 15.5 2.5 0.01 15.2 1.7 1.2 1 0 0 1 1 1 1 Glycoprotein UL132 SSP160 PF06933.6 EEQ35568.1 - 0.014 13.4 7.8 0.019 12.9 5.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 EEQ35568.1 - 0.72 7.6 11.3 0.96 7.2 7.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.3 EEQ35568.1 - 8 5.5 10.6 11 5.0 7.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cnd1 PF12717.2 EEQ35570.1 - 2.2e-53 180.7 7.7 4.1e-50 170.1 0.6 3.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EEQ35570.1 - 3.8e-47 160.0 1.9 4.8e-47 159.7 0.1 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EEQ35570.1 - 4.2e-12 46.1 0.6 8.9e-05 22.6 0.0 4.9 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EEQ35570.1 - 9e-08 31.5 10.6 0.054 13.6 0.0 6.4 7 0 0 7 7 7 3 HEAT repeat DUF2435 PF10363.4 EEQ35570.1 - 4.6e-05 23.2 0.1 3.5 7.5 0.0 4.5 3 1 1 4 4 4 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EEQ35570.1 - 4.9e-05 23.6 9.4 0.17 12.3 0.0 5.9 6 0 0 6 6 6 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EEQ35570.1 - 0.0057 16.5 1.1 6 6.9 0.1 4.3 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 EEQ35570.1 - 0.22 10.4 11.0 0.13 11.2 1.5 4.0 3 2 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Pkinase PF00069.20 EEQ35571.1 - 9.5e-37 126.5 0.0 8.7e-36 123.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35571.1 - 5.5e-11 42.0 0.0 4.4e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ35571.1 - 0.023 13.6 0.0 4.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Nop14 PF04147.7 EEQ35571.1 - 0.51 8.2 15.1 0.68 7.7 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.7 EEQ35571.1 - 2.2 6.9 11.3 3.1 6.4 7.9 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein PCMT PF01135.14 EEQ35572.1 - 1.4e-61 207.6 0.0 1.8e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EEQ35572.1 - 3.1e-10 40.6 0.1 4.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ35572.1 - 1.5e-07 31.1 0.1 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ35572.1 - 6.7e-06 25.9 0.0 9.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEQ35572.1 - 4.1e-05 23.2 0.0 6.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ35572.1 - 7.7e-05 22.7 0.1 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ35572.1 - 0.00073 19.9 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ35572.1 - 0.0021 17.4 0.0 0.0047 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EEQ35572.1 - 0.0031 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EEQ35572.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EEQ35572.1 - 0.02 15.3 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ35572.1 - 0.029 14.7 0.0 0.062 13.6 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain CMAS PF02353.15 EEQ35572.1 - 0.066 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EEQ35572.1 - 0.082 13.7 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EEQ35572.1 - 0.1 11.2 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DnaJ PF00226.26 EEQ35573.1 - 7.5e-24 83.2 1.8 7.5e-24 83.2 1.3 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EEQ35573.1 - 1.8e-23 81.9 12.2 9.2e-10 38.0 0.1 6.1 6 1 1 7 7 6 4 TPR repeat TPR_1 PF00515.23 EEQ35573.1 - 1.5e-19 68.7 2.7 1e-05 24.8 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ35573.1 - 3.2e-17 60.9 12.5 0.00019 21.1 0.0 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ35573.1 - 9.6e-16 57.3 3.9 0.00078 19.2 0.1 4.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ35573.1 - 1.8e-15 55.9 5.7 0.056 14.0 0.1 7.9 3 3 5 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ35573.1 - 9e-15 54.8 9.4 0.00019 22.0 2.5 5.8 5 1 1 6 6 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ35573.1 - 4.8e-13 47.8 2.5 0.0045 16.6 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ35573.1 - 1.2e-10 41.5 8.1 0.08 13.2 0.0 5.4 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ35573.1 - 2e-09 37.2 5.9 1.4 9.5 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ35573.1 - 5.2e-07 29.3 2.9 0.2 11.9 0.0 5.8 7 0 0 7 7 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EEQ35573.1 - 8.5e-07 29.0 10.8 0.1 12.7 0.0 5.1 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EEQ35573.1 - 6e-06 25.6 3.8 5.4 7.0 0.0 6.5 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ35573.1 - 0.00044 20.1 13.4 0.38 10.7 0.0 6.0 4 2 2 6 6 5 1 Tetratricopeptide repeat SLS PF14611.1 EEQ35573.1 - 0.0022 17.4 2.9 0.0025 17.2 0.9 1.7 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator MIT PF04212.13 EEQ35573.1 - 0.0076 16.1 0.6 0.057 13.3 0.4 2.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Syntaxin_2 PF14523.1 EEQ35573.1 - 0.012 15.6 9.0 0.8 9.7 2.1 3.0 3 0 0 3 3 2 0 Syntaxin-like protein TPR_20 PF14561.1 EEQ35573.1 - 0.014 15.5 2.9 4.6 7.4 0.0 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EEQ35573.1 - 0.16 12.1 7.3 3.7 7.7 0.3 3.5 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation HemY_N PF07219.8 EEQ35573.1 - 2.3 7.8 5.3 4.4 6.9 0.4 2.7 2 0 0 2 2 2 0 HemY protein N-terminus RF-1 PF00472.15 EEQ35574.1 - 2.8e-33 114.0 0.9 6.1e-33 113.0 0.7 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EEQ35574.1 - 6.5e-27 93.5 0.0 3.3e-26 91.2 0.0 2.1 2 0 0 2 2 2 1 PCRF domain HHA PF05321.6 EEQ35574.1 - 0.039 14.1 0.8 7.4 6.7 0.2 2.8 2 0 0 2 2 2 0 Haemolysin expression modulating protein Abdominal-A PF12407.3 EEQ35574.1 - 1.2 8.6 7.6 3 7.4 5.3 1.6 1 0 0 1 1 1 0 Homeobox protein Mito_carr PF00153.22 EEQ35575.1 - 7.1e-45 150.6 4.1 1.4e-24 85.6 0.0 4.5 4 1 0 4 4 4 4 Mitochondrial carrier protein Helicase_C PF00271.26 EEQ35576.1 - 6.9e-24 83.5 0.1 1.1e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ35576.1 - 2.1e-17 63.1 0.1 3.2e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase COX14 PF14880.1 EEQ35576.1 - 0.17 11.5 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly SMC_N PF02463.14 EEQ35577.1 - 2.5e-23 82.4 1.3 3e-22 78.9 0.9 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEQ35577.1 - 4.2e-11 43.5 58.5 6.9e-11 42.8 17.2 4.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EEQ35577.1 - 5.6e-09 36.3 0.0 5.8e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EEQ35577.1 - 0.0004 19.5 0.0 0.0004 19.5 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EEQ35577.1 - 0.00046 19.6 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EEQ35577.1 - 0.0018 18.1 0.0 0.0018 18.1 0.0 3.0 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 EEQ35577.1 - 0.092 13.0 0.3 0.092 13.0 0.2 5.3 3 2 0 3 3 3 0 ABC transporter AAA_13 PF13166.1 EEQ35577.1 - 8.8 4.6 72.3 0.016 13.6 4.3 5.0 3 2 1 4 4 4 0 AAA domain NUDIX PF00293.23 EEQ35578.1 - 1.5e-11 44.0 0.5 8.9e-11 41.5 0.3 1.9 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EEQ35578.1 - 0.018 14.4 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 NUDIX domain SNARE PF05739.14 EEQ35581.1 - 1.5e-17 63.0 0.6 1.5e-17 63.0 0.4 3.1 3 1 1 4 4 4 1 SNARE domain Syntaxin PF00804.20 EEQ35581.1 - 3.8e-08 33.4 3.9 0.00027 21.0 0.1 4.2 3 1 1 4 4 4 2 Syntaxin Baculo_PEP_C PF04513.7 EEQ35581.1 - 0.00046 20.0 0.6 0.059 13.1 0.0 2.9 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.16 EEQ35581.1 - 0.0015 18.1 4.2 0.0081 15.7 0.2 2.5 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 EEQ35581.1 - 0.01 16.0 1.8 5.8 7.2 0.0 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FliT PF05400.8 EEQ35581.1 - 0.035 14.4 5.4 1.8 9.0 0.1 3.6 4 0 0 4 4 4 0 Flagellar protein FliT Syntaxin-18_N PF10496.4 EEQ35581.1 - 5.8 6.8 8.4 1.2 9.0 0.3 3.2 3 2 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus SUR7 PF06687.7 EEQ35582.1 - 1.3e-29 103.2 5.0 1.7e-29 102.9 3.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 EEQ35582.1 - 1.4 9.0 6.0 0.15 12.1 0.4 2.0 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding AAA_10 PF12846.2 EEQ35583.1 - 2.5e-08 33.7 0.1 0.0002 20.9 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EEQ35583.1 - 0.001 18.5 0.0 0.046 13.1 0.0 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EEQ35583.1 - 0.0056 16.8 0.1 3 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EEQ35583.1 - 0.044 13.9 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EEQ35583.1 - 0.13 11.8 0.1 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_hydro_18 PF00704.23 EEQ35584.1 - 1.9e-15 57.2 1.2 1.1e-14 54.6 0.1 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 adh_short PF00106.20 EEQ35585.1 - 3.4e-26 92.1 0.2 4.2e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ35585.1 - 5.5e-11 42.4 0.0 7.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ35585.1 - 1.5e-08 34.7 0.0 1.9e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EEQ35585.1 - 0.00037 19.7 0.0 0.00052 19.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EEQ35585.1 - 0.0017 17.8 0.1 0.028 13.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEQ35585.1 - 0.052 13.3 0.2 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase APH PF01636.18 EEQ35586.1 - 2.9e-19 69.7 0.0 4e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35586.1 - 2.7e-09 36.9 0.0 3.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EEQ35586.1 - 0.00024 20.1 0.0 0.23 10.4 0.0 2.1 2 0 0 2 2 2 2 Fructosamine kinase EcKinase PF02958.15 EEQ35586.1 - 0.01 15.0 0.1 0.021 14.0 0.0 1.4 2 0 0 2 2 2 0 Ecdysteroid kinase Pkinase PF00069.20 EEQ35586.1 - 0.02 14.0 0.0 0.95 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 EEQ35586.1 - 0.069 11.7 0.0 0.98 7.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Ion_trans_2 PF07885.11 EEQ35588.1 - 4.1e-23 80.8 27.0 6.5e-15 54.6 6.1 3.1 3 1 0 3 3 3 2 Ion channel APH PF01636.18 EEQ35590.1 - 1.7e-12 47.6 0.0 2.3e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ35590.1 - 7.8e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ35590.1 - 0.015 14.4 0.0 0.78 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF4325 PF14213.1 EEQ35590.1 - 0.066 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) WaaY PF06176.6 EEQ35590.1 - 0.067 12.4 0.0 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) RTA1 PF04479.8 EEQ35591.1 - 2.7e-46 157.8 6.5 3.6e-46 157.4 4.5 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3040 PF11239.3 EEQ35591.1 - 0.075 13.0 8.4 0.17 11.9 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) NfeD PF01957.13 EEQ35591.1 - 0.28 11.3 0.1 0.28 11.3 0.1 3.0 2 2 1 3 3 3 0 NfeD-like C-terminal, partner-binding NnrU PF07298.6 EEQ35591.1 - 0.33 10.3 10.7 0.041 13.2 1.4 2.6 1 1 1 2 2 2 0 NnrU protein DctQ PF04290.7 EEQ35591.1 - 5.3 6.7 19.9 2.5 7.8 2.7 3.2 1 1 2 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3433 PF11915.3 EEQ35592.1 - 2.6e-30 104.4 11.4 1.4e-24 86.0 1.2 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) zf-RanBP PF00641.13 EEQ35593.1 - 2.1e-09 36.3 1.5 3.5e-09 35.6 1.0 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch PF01585.18 EEQ35593.1 - 4.9e-09 35.8 2.8 1.3e-08 34.4 1.9 1.8 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 EEQ35593.1 - 7e-08 32.3 0.0 2.7e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ35593.1 - 9.4e-06 25.1 0.0 2.8e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EEQ35593.1 - 0.00012 21.8 1.1 0.00055 19.7 0.8 2.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site Rad50_zn_hook PF04423.9 EEQ35593.1 - 0.029 13.8 0.9 0.11 11.9 0.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-met PF12874.2 EEQ35593.1 - 1.9 8.8 7.4 35 4.7 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Nucleo_P87 PF07267.6 EEQ35595.1 - 0.089 11.4 1.7 0.083 11.5 1.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SLAC1 PF03595.12 EEQ35596.1 - 2.9e-98 328.5 58.0 3.4e-98 328.3 40.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PsbN PF02468.10 EEQ35596.1 - 3.8 7.2 7.7 2.4 7.8 0.7 3.0 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) zf-DHHC PF01529.15 EEQ35596.1 - 9.8 5.5 10.8 14 5.0 0.1 3.2 2 1 0 2 2 2 0 DHHC palmitoyltransferase Pkinase PF00069.20 EEQ35597.1 - 1.7e-22 79.8 0.0 2.2e-21 76.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35597.1 - 3.6e-06 26.2 0.0 0.23 10.5 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 EEQ35597.1 - 0.0026 16.7 0.0 0.011 14.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ35597.1 - 0.0077 15.9 0.3 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family MoaE PF02391.12 EEQ35598.1 - 7.5e-29 99.9 0.0 8.9e-29 99.6 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.9 EEQ35599.1 - 4.9e-59 198.8 0.0 6.5e-59 198.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EEQ35599.1 - 0.00011 21.8 0.0 0.00024 20.7 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EEQ35599.1 - 0.00053 20.0 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Yae1_N PF09811.4 EEQ35602.1 - 7e-12 44.6 0.4 1.1e-11 44.0 0.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Kdo PF06293.9 EEQ35603.1 - 9.5e-05 21.5 0.1 0.00026 20.1 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ35603.1 - 0.00012 21.9 0.1 0.00012 21.9 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ35603.1 - 0.00068 19.0 0.0 0.0017 17.7 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EEQ35603.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ35603.1 - 0.18 10.4 0.0 0.32 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) FadA PF09403.5 EEQ35603.1 - 1.4 8.9 10.3 2.7 7.9 7.1 1.4 1 0 0 1 1 1 0 Adhesion protein FadA MFS_1 PF07690.11 EEQ35604.1 - 1.8e-31 109.1 26.9 1.8e-31 109.1 18.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 EEQ35605.1 - 1.3e-175 583.8 0.6 4.2e-76 256.0 0.0 3.5 4 0 0 4 4 4 3 AMP-binding enzyme Condensation PF00668.15 EEQ35605.1 - 2.2e-110 368.2 0.0 1.1e-36 126.2 0.0 5.0 5 1 0 5 5 5 4 Condensation domain PP-binding PF00550.20 EEQ35605.1 - 2.6e-24 85.2 0.3 2.4e-13 50.1 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site IIGP PF05049.8 EEQ35605.1 - 0.3 9.8 0.0 0.59 8.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EEQ35606.1 - 4.8e-44 149.9 0.0 7.6e-22 78.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ35606.1 - 1.2e-21 77.3 35.1 2.7e-21 76.2 8.6 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EEQ35606.1 - 7.3e-09 35.1 0.0 0.0015 17.8 0.0 3.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ35606.1 - 8.5e-08 32.4 0.1 0.043 13.7 0.1 4.1 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EEQ35606.1 - 8.3e-05 22.6 1.3 0.025 14.5 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain AAA_25 PF13481.1 EEQ35606.1 - 0.00034 20.0 0.0 0.0011 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEQ35606.1 - 0.0011 18.4 0.2 0.0085 15.5 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEQ35606.1 - 0.0043 17.1 0.1 0.046 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EEQ35606.1 - 0.01 15.7 0.1 8.9 6.3 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EEQ35606.1 - 0.011 14.9 0.0 0.051 12.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEQ35606.1 - 0.012 15.1 0.3 0.04 13.3 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EEQ35606.1 - 0.015 16.1 0.1 0.17 12.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EEQ35606.1 - 0.027 14.2 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.1 EEQ35606.1 - 0.028 14.7 0.3 0.085 13.1 0.2 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEQ35606.1 - 0.066 12.9 0.2 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_33 PF13671.1 EEQ35606.1 - 0.095 12.5 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EEQ35606.1 - 0.099 12.9 0.0 0.48 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 EEQ35606.1 - 0.1 11.2 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein cobW PF02492.14 EEQ35606.1 - 0.16 11.4 0.2 0.39 10.1 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EEQ35606.1 - 0.17 11.8 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Abhydrolase_4 PF08386.5 EEQ35609.1 - 3.2e-15 55.8 0.0 6.4e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EEQ35609.1 - 2.7e-10 40.1 0.0 4.3e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ35609.1 - 5.1e-05 23.2 0.1 0.00018 21.4 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ35609.1 - 0.038 13.7 0.0 0.58 9.9 0.0 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Beta-lactamase PF00144.19 EEQ35612.1 - 5.5e-48 163.6 0.0 1.1e-46 159.4 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 EEQ35612.1 - 9.8e-08 31.7 0.1 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Ank_2 PF12796.2 EEQ35613.1 - 2.1e-67 223.4 1.6 7.6e-22 77.4 0.1 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ35613.1 - 1.3e-56 185.6 1.9 6.5e-12 44.6 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EEQ35613.1 - 1.3e-42 143.4 0.2 8.5e-13 48.4 0.0 5.6 3 2 1 5 5 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ35613.1 - 9.8e-41 133.7 0.2 7.3e-07 28.8 0.0 7.2 7 0 0 7 7 6 6 Ankyrin repeat Ank_5 PF13857.1 EEQ35613.1 - 3.5e-40 135.1 5.0 5.1e-09 36.0 0.0 6.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) NACHT PF05729.7 EEQ35613.1 - 2.9e-13 49.8 0.0 7e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEQ35613.1 - 4.5e-06 26.7 0.1 2.6e-05 24.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ35613.1 - 0.00026 21.1 0.0 0.00087 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EEQ35613.1 - 0.0068 15.3 0.0 0.017 14.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 EEQ35613.1 - 0.016 14.2 0.0 0.9 8.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 EEQ35613.1 - 0.022 14.9 0.0 0.084 13.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.1 EEQ35613.1 - 0.022 14.6 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEQ35613.1 - 0.036 14.2 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EEQ35613.1 - 0.048 12.6 0.0 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EEQ35613.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EEQ35613.1 - 0.17 11.3 0.6 17 4.8 0.0 3.2 2 1 0 3 3 3 0 FtsK/SpoIIIE family adh_short_C2 PF13561.1 EEQ35614.1 - 3.9e-32 111.9 0.0 5e-31 108.3 0.0 2.6 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EEQ35614.1 - 1.2e-20 74.1 0.0 2.5e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEQ35614.1 - 8.2e-11 41.7 0.0 1.9e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EEQ35614.1 - 1.1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ35614.1 - 0.023 14.3 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 KR domain Aminotran_4 PF01063.14 EEQ35615.1 - 1.6e-26 93.1 0.0 2.3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV ABC_tran PF00005.22 EEQ35617.1 - 1.1e-47 161.8 0.0 2.1e-28 99.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ35617.1 - 3.5e-36 125.0 24.8 1.8e-23 83.3 8.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEQ35617.1 - 9e-11 42.2 0.3 0.072 13.0 0.0 4.3 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EEQ35617.1 - 4.1e-10 39.2 5.1 0.00058 19.1 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEQ35617.1 - 1.3e-06 27.7 0.3 0.00079 18.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ35617.1 - 1.5e-06 28.3 0.0 0.06 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EEQ35617.1 - 4.2e-06 26.0 0.1 0.018 14.2 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Miro PF08477.8 EEQ35617.1 - 7.9e-06 26.3 0.0 0.06 13.8 0.0 3.2 3 0 0 3 3 2 2 Miro-like protein AAA_23 PF13476.1 EEQ35617.1 - 9.9e-05 22.7 2.5 0.29 11.4 0.2 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ35617.1 - 0.00013 21.8 0.0 0.055 13.4 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEQ35617.1 - 0.00095 19.3 0.7 2.7 8.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EEQ35617.1 - 0.0011 19.7 0.8 0.47 11.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EEQ35617.1 - 0.0012 19.0 0.6 1.3 9.2 0.1 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEQ35617.1 - 0.0017 17.4 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 EEQ35617.1 - 0.0027 17.5 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEQ35617.1 - 0.0056 16.4 0.9 0.027 14.1 0.0 2.4 3 0 0 3 3 2 1 Archaeal ATPase AAA_15 PF13175.1 EEQ35617.1 - 0.0058 15.7 0.8 0.44 9.5 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 EEQ35617.1 - 0.0063 16.2 0.8 3.1 7.4 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EEQ35617.1 - 0.016 15.0 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 EEQ35617.1 - 0.019 14.8 0.3 0.36 10.7 0.0 3.0 4 0 0 4 4 2 0 AAA domain T2SE PF00437.15 EEQ35617.1 - 0.02 13.8 0.4 4.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 EEQ35617.1 - 0.02 14.3 0.1 9 5.7 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EEQ35617.1 - 0.022 15.0 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEQ35617.1 - 0.031 13.1 0.1 2.6 6.8 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 EEQ35617.1 - 0.038 13.4 0.2 0.98 8.9 0.0 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EEQ35617.1 - 0.046 13.1 0.0 5.1 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 EEQ35617.1 - 0.067 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) NTPase_1 PF03266.10 EEQ35617.1 - 0.077 12.7 0.5 12 5.5 0.1 2.6 2 0 0 2 2 2 0 NTPase Gtr1_RagA PF04670.7 EEQ35617.1 - 0.13 11.3 0.2 0.27 10.3 0.2 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EEQ35617.1 - 0.2 11.8 0.1 10 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ABC_ATPase PF09818.4 EEQ35617.1 - 0.5 8.9 1.5 1.8 7.0 0.0 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF2207 PF09972.4 EEQ35617.1 - 2.5 6.6 5.4 0.5 8.8 0.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RTA1 PF04479.8 EEQ35618.1 - 1.7e-35 122.5 3.7 2.6e-35 121.9 2.5 1.2 1 0 0 1 1 1 1 RTA1 like protein 4HBT_2 PF13279.1 EEQ35619.1 - 1.7e-07 31.7 0.0 2.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_transf_1 PF00698.16 EEQ35620.1 - 5.4e-58 196.8 0.0 2.3e-55 188.1 0.0 2.6 2 0 0 2 2 2 2 Acyl transferase domain DUF1729 PF08354.5 EEQ35620.1 - 9.1e-29 99.0 0.0 2.4e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 EEQ35620.1 - 1.2e-23 82.7 0.1 5.4e-23 80.6 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EEQ35620.1 - 4.9e-19 68.4 0.0 4.9e-18 65.1 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase p450 PF00067.17 EEQ35621.1 - 1.1e-54 185.7 0.0 4e-54 183.8 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 AMP-binding PF00501.23 EEQ35622.1 - 0 1337.7 0.0 3.4e-83 279.3 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 EEQ35622.1 - 2.2e-266 880.4 0.0 1e-48 165.7 0.0 7.6 7 1 0 7 7 7 7 Condensation domain PP-binding PF00550.20 EEQ35622.1 - 7.7e-56 186.2 7.7 1.3e-10 41.4 0.0 7.1 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ35622.1 - 1.2e-32 112.6 0.0 2.3e-07 31.6 0.0 6.2 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EEQ35622.1 - 1.3e-05 25.3 0.0 0.14 12.4 0.0 4.2 4 0 0 4 4 4 1 HxxPF-repeated domain Fis1_TPR_N PF14852.1 EEQ35622.1 - 0.067 12.5 0.1 11 5.3 0.0 2.9 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat Transferase PF02458.10 EEQ35622.1 - 0.14 10.5 0.0 14 3.9 0.0 2.7 3 0 0 3 3 3 0 Transferase family Csm1 PF12539.3 EEQ35622.1 - 0.52 10.8 1.5 79 3.8 0.0 3.8 4 0 0 4 4 4 0 Chromosome segregation protein Csm1/Pcs1 ASC PF00858.19 EEQ35622.1 - 1.3 7.5 0.2 2.3 6.7 0.1 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Pescadillo_N PF06732.6 EEQ35622.1 - 3 7.0 0.3 16 4.6 0.2 2.0 2 0 0 2 2 2 0 Pescadillo N-terminus Trehalase PF01204.13 EEQ35622.1 - 5.5 5.5 0.0 9 4.8 0.0 1.2 1 0 0 1 1 1 0 Trehalase F-box-like PF12937.2 EEQ35623.1 - 5.9e-05 22.7 4.3 0.00062 19.4 3.0 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ35623.1 - 0.022 14.3 2.4 0.6 9.8 1.4 3.1 2 1 0 2 2 2 0 F-box domain YejG PF13989.1 EEQ35623.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein Glyco_hydro_18 PF00704.23 EEQ35624.1 - 4.3e-53 180.9 0.1 1.3e-27 97.1 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EEQ35624.1 - 0.0087 16.0 1.5 0.0087 16.0 1.0 3.9 4 0 0 4 4 4 2 Chitin recognition protein LysM PF01476.15 EEQ35626.1 - 5.9e-30 102.9 0.4 9e-09 35.0 0.1 4.3 4 0 0 4 4 4 4 LysM domain Fungal_trans PF04082.13 EEQ35627.1 - 5.4e-11 41.8 1.2 5.8e-11 41.7 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pyr_redox PF00070.22 EEQ35628.1 - 1.5e-15 57.3 0.0 2.8e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ35628.1 - 1.7e-12 47.6 0.0 7.5e-12 45.5 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ35628.1 - 1.4e-06 27.4 0.0 0.00051 19.0 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EEQ35628.1 - 7.3e-06 26.1 0.0 0.0008 19.5 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EEQ35628.1 - 0.0039 17.1 0.0 0.43 10.5 0.0 2.9 3 0 0 3 3 3 1 TrkA-N domain COX3 PF00510.13 EEQ35628.1 - 0.0068 15.8 0.0 0.0092 15.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Trp_halogenase PF04820.9 EEQ35628.1 - 0.013 14.1 0.1 1.2 7.6 0.0 2.9 2 1 1 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EEQ35628.1 - 0.025 13.4 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 EEQ35628.1 - 0.031 13.1 0.1 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Methyltransf_2 PF00891.13 EEQ35629.1 - 4.3e-14 52.3 0.0 1.3e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase HTH_AsnC-type PF13404.1 EEQ35629.1 - 0.069 12.6 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain adh_short PF00106.20 EEQ35630.1 - 1.1e-11 44.9 0.4 2.3e-11 43.9 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ35630.1 - 2e-06 27.7 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ35630.1 - 0.00011 21.9 0.1 0.0003 20.5 0.0 1.7 1 1 1 2 2 2 1 KR domain MFS_1 PF07690.11 EEQ35631.1 - 2.2e-45 154.9 38.7 2.2e-45 154.9 26.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ35631.1 - 7e-09 34.7 34.4 2.6e-08 32.8 23.8 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EEQ35631.1 - 0.00093 17.4 6.5 0.00093 17.4 4.5 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.15 EEQ35631.1 - 0.0046 15.0 16.7 0.0032 15.6 5.9 2.7 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.23 EEQ35632.1 - 4e-75 252.7 0.0 6.5e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EEQ35632.1 - 5.6e-73 245.5 0.0 1.1e-72 244.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ35632.1 - 1.6e-50 172.2 0.0 3.9e-50 170.9 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 EEQ35632.1 - 2.5e-50 171.0 0.1 4.1e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 EEQ35632.1 - 2.5e-43 147.8 0.0 1.5e-42 145.3 0.0 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EEQ35632.1 - 1.3e-42 145.9 0.0 2.4e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EEQ35632.1 - 1.1e-35 122.9 0.1 7.3e-34 117.0 0.0 3.2 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEQ35632.1 - 1e-30 106.0 0.3 4e-30 104.0 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EEQ35632.1 - 4e-24 84.8 0.0 1e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EEQ35632.1 - 3.9e-18 65.4 2.7 9.7e-10 38.5 0.0 4.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EEQ35632.1 - 1.1e-17 64.2 0.0 3.6e-17 62.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EEQ35632.1 - 3.9e-13 49.4 0.0 6.3e-11 42.1 0.0 2.7 3 0 0 3 3 2 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 EEQ35632.1 - 1.7e-12 47.3 0.0 3.8e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EEQ35632.1 - 1.6e-11 44.3 0.0 3.8e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 EEQ35632.1 - 2.9e-09 37.3 0.0 7.7e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ35632.1 - 5.8e-08 33.3 0.0 2.4e-07 31.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ35632.1 - 2.4e-07 30.4 0.0 6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ35632.1 - 2e-06 28.0 0.0 1.5e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ35632.1 - 8.5e-06 25.0 0.0 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EEQ35632.1 - 3.5e-05 22.9 0.0 7.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 EEQ35632.1 - 0.0026 16.8 0.0 0.0054 15.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EEQ35632.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.14 EEQ35632.1 - 0.021 13.5 0.0 1.9 7.1 0.0 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EEQ35632.1 - 0.068 14.1 0.0 0.35 11.8 0.0 2.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Methyltransf_8 PF05148.10 EEQ35632.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_16 PF10294.4 EEQ35632.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF1196 PF06709.6 EEQ35632.1 - 0.34 10.8 0.0 0.9 9.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1196) ADH_N PF08240.7 EEQ35633.1 - 1.4e-07 31.2 0.5 7.7e-07 28.8 0.4 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ35633.1 - 2.5e-05 23.8 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.17 EEQ35634.1 - 8.1e-17 60.8 0.0 3.9e-14 52.0 0.0 2.8 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EEQ35635.1 - 1.8e-44 152.0 0.0 2.1e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 EEQ35636.1 - 1.9e-07 30.8 8.4 3.4e-07 30.0 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HNH_2 PF13391.1 EEQ35637.1 - 2.2e-15 56.1 0.1 5.1e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.20 EEQ35638.1 - 2.5e-26 92.3 0.0 7.2e-26 90.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35638.1 - 2.5e-09 36.5 0.1 1.1e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEQ35638.1 - 0.0045 16.7 1.2 0.068 12.8 0.2 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ35638.1 - 0.019 13.9 0.1 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like ASFV_p27 PF06556.6 EEQ35638.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus Myb_DNA-binding PF00249.26 EEQ35639.1 - 1.7e-05 24.7 0.4 4.1e-05 23.5 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ35639.1 - 0.00012 22.1 0.2 0.00024 21.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EEQ35639.1 - 0.0042 16.9 1.1 0.013 15.3 0.7 1.8 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MFS_1 PF07690.11 EEQ35640.1 - 1.3e-28 99.7 54.5 1.3e-28 99.7 37.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 EEQ35641.1 - 8.2e-37 126.5 0.0 1.4e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEQ35641.1 - 1.3e-33 116.0 0.0 2.3e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EEQ35641.1 - 2.3e-08 33.7 0.0 6.6e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EEQ35641.1 - 5.5e-08 32.9 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EEQ35641.1 - 0.004 17.0 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EEQ35641.1 - 0.013 14.1 0.0 0.027 13.1 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEQ35641.1 - 0.013 14.3 0.0 0.088 11.6 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EEQ35641.1 - 0.032 13.1 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEQ35641.1 - 0.16 11.9 0.2 0.97 9.4 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding Aldo_ket_red PF00248.16 EEQ35642.1 - 1.4e-65 220.8 0.0 2.6e-65 220.0 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Methyltransf_3 PF01596.12 EEQ35643.1 - 3.3e-34 117.7 0.0 3.8e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EEQ35643.1 - 7.8e-14 52.3 0.0 1.2e-13 51.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ35643.1 - 3.1e-11 43.8 0.0 5.6e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ35643.1 - 8.2e-11 41.7 0.0 1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ35643.1 - 9.1e-08 32.1 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ35643.1 - 1e-07 31.6 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 EEQ35643.1 - 5.3e-06 25.9 0.0 7e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 EEQ35643.1 - 0.00048 19.8 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ35643.1 - 0.0006 20.1 0.0 0.00089 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ35643.1 - 0.00085 19.7 0.0 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ35643.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EEQ35643.1 - 0.0026 18.1 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEQ35643.1 - 0.0043 16.7 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EEQ35643.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_15 PF09445.5 EEQ35643.1 - 0.029 13.9 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EEQ35643.1 - 0.048 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Spermine_synth PF01564.12 EEQ35643.1 - 0.059 12.2 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase NAD_binding_4 PF07993.7 EEQ35644.1 - 6.3e-31 107.1 0.0 9.4e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EEQ35644.1 - 6.8e-19 67.5 0.1 2e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EEQ35644.1 - 5.5e-09 35.8 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EEQ35644.1 - 2.7e-07 30.7 0.2 8.1e-07 29.2 0.1 1.8 1 1 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 EEQ35644.1 - 0.0013 18.3 0.1 0.0082 15.8 0.1 2.0 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EEQ35644.1 - 0.0016 18.4 0.1 0.01 15.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase IPT PF01745.11 EEQ35644.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Polysacc_synt_2 PF02719.10 EEQ35644.1 - 0.19 10.6 0.0 0.38 9.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Bactofilin PF04519.8 EEQ35644.1 - 0.26 11.2 1.4 0.63 10.0 1.0 1.6 1 0 0 1 1 1 0 Polymer-forming cytoskeletal ADH_N PF08240.7 EEQ35645.1 - 1.6e-24 85.7 6.0 2.7e-24 85.0 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ35645.1 - 7.1e-18 64.4 0.0 1.1e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEQ35645.1 - 0.00023 20.3 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EEQ35645.1 - 0.0086 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding ELFV_dehydrog PF00208.16 EEQ35645.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.20 EEQ35645.1 - 0.022 14.6 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.13 EEQ35646.1 - 1.6e-23 82.8 3.6 2.7e-23 82.1 2.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.7 EEQ35646.1 - 0.028 14.1 2.3 0.079 12.7 1.6 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CCDC92 PF14916.1 EEQ35646.1 - 0.046 13.3 0.4 0.12 12.0 0.3 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function GMC_oxred_N PF00732.14 EEQ35647.1 - 7.2e-49 166.5 0.0 1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ35647.1 - 4.3e-38 130.8 0.0 7.4e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EEQ35647.1 - 9.1e-07 28.0 0.7 0.0014 17.5 0.6 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEQ35647.1 - 2.3e-05 23.4 0.1 0.00052 19.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ35647.1 - 0.00019 21.4 0.4 0.00064 19.7 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ35647.1 - 0.0011 18.8 0.4 0.0023 17.8 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEQ35647.1 - 0.0033 16.1 0.9 0.0048 15.5 0.6 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EEQ35647.1 - 0.0036 16.2 0.3 0.0065 15.4 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EEQ35647.1 - 0.0045 17.0 0.2 0.38 10.7 0.1 3.1 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ35647.1 - 0.037 13.1 0.1 0.11 11.5 0.1 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 EEQ35647.1 - 0.075 12.8 0.3 0.18 11.5 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EEQ35647.1 - 0.079 11.4 0.2 0.12 10.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein CHU_C PF13585.1 EEQ35650.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of CHU protein family Glyco_hydro_18 PF00704.23 EEQ35652.1 - 1.7e-51 175.7 2.6 2.5e-51 175.1 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEQ35652.1 - 1.5e-16 59.9 0.2 5.7e-05 22.9 0.0 3.6 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.14 EEQ35652.1 - 0.00012 21.9 3.0 0.00012 21.9 2.1 4.3 4 0 0 4 4 4 1 Chitin recognition protein DUF4470 PF14737.1 EEQ35655.1 - 5.6e-27 93.3 0.0 1e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Abhydrolase_6 PF12697.2 EEQ35656.1 - 0.00058 19.7 0.0 0.00073 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ35656.1 - 0.0079 15.8 0.0 0.02 14.5 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Ank_2 PF12796.2 EEQ35657.1 - 2e-51 172.2 1.8 1.1e-15 57.7 0.0 4.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ35657.1 - 9.8e-30 102.3 6.3 1.2e-13 51.1 0.1 5.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 EEQ35657.1 - 1e-28 97.6 6.0 2.4e-06 27.0 0.0 6.5 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EEQ35657.1 - 1.1e-20 73.1 1.0 1.3e-07 31.6 0.2 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ35657.1 - 2.8e-20 70.3 3.4 0.00034 20.5 0.0 6.5 6 0 0 6 6 5 4 Ankyrin repeat NACHT PF05729.7 EEQ35657.1 - 1e-06 28.5 0.0 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EEQ35657.1 - 0.0001 22.4 0.0 0.003 17.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EEQ35657.1 - 0.00018 21.5 0.1 0.0017 18.3 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EEQ35657.1 - 0.036 13.9 0.0 0.13 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EEQ35657.1 - 0.17 11.9 0.0 1.6 8.7 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA PF00004.24 EEQ35657.1 - 0.17 12.0 0.0 0.74 10.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEQ35657.1 - 0.19 11.4 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Cauli_VI PF01693.11 EEQ35658.1 - 8.1e-24 83.3 4.0 8.2e-14 51.3 0.7 2.2 2 0 0 2 2 2 2 Caulimovirus viroplasmin SAICAR_synt PF01259.13 EEQ35658.1 - 0.068 12.2 0.1 0.32 10.0 0.1 1.8 1 1 0 1 1 1 0 SAICAR synthetase CorA PF01544.13 EEQ35659.1 - 0.0056 15.7 0.0 0.0094 15.0 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PEMT PF04191.8 EEQ35663.1 - 1.1e-32 112.2 2.6 1.7e-32 111.6 1.2 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase RXT2_N PF08595.6 EEQ35664.1 - 1.9e-29 102.3 0.1 1.9e-29 102.3 0.1 1.9 2 0 0 2 2 2 1 RXT2-like, N-terminal Ribosomal_L6 PF00347.18 EEQ35665.1 - 4.6e-23 81.5 5.7 5.8e-11 42.7 0.4 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Glutaredoxin PF00462.19 EEQ35666.1 - 5e-12 45.6 0.0 1.1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EEQ35666.1 - 0.023 14.8 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Abhydrolase_6 PF12697.2 EEQ35667.1 - 1.3e-18 67.7 0.9 5.9e-18 65.5 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ35667.1 - 1.1e-07 31.7 0.0 3.3e-06 26.9 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ35667.1 - 1e-06 28.4 0.0 3.5e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold PDE8 PF08629.5 EEQ35667.1 - 2.1 8.2 7.0 0.41 10.4 1.5 2.4 2 0 0 2 2 2 0 PDE8 phosphodiesterase DivIC PF04977.10 EEQ35667.1 - 4.2 6.9 5.4 7.7 6.0 3.7 1.3 1 0 0 1 1 1 0 Septum formation initiator Gryzun PF07919.7 EEQ35668.1 - 1.3e-130 436.3 0.0 1.7e-130 436.0 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EEQ35668.1 - 2.9e-83 279.1 0.2 1.6e-74 250.4 0.2 2.6 3 0 0 3 3 3 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EEQ35668.1 - 0.016 15.0 0.0 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking PhoD PF09423.5 EEQ35669.1 - 2e-10 39.8 0.5 3e-07 29.3 0.2 2.4 2 1 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.17 EEQ35670.1 - 2.2e-12 47.2 4.4 3.4e-12 46.5 3.1 1.3 1 0 0 1 1 1 1 Rhomboid family NIF PF03031.13 EEQ35672.1 - 6.6e-53 178.6 0.0 9.8e-53 178.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aminotran_5 PF00266.14 EEQ35673.1 - 2.6e-25 88.9 0.0 3.4e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EEQ35673.1 - 0.0071 16.2 0.1 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain adh_short PF00106.20 EEQ35673.1 - 0.043 13.7 0.1 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EEQ35673.1 - 0.082 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 KR domain HECT PF00632.20 EEQ35675.1 - 4.5e-95 318.4 0.0 6.3e-95 317.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EEQ35675.1 - 7.1e-33 112.0 25.4 1.2e-11 44.1 2.6 4.5 4 0 0 4 4 4 3 WW domain C2 PF00168.25 EEQ35675.1 - 6.7e-15 54.7 0.0 1.7e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 EEQ35676.1 - 1.4e-15 56.6 0.0 2.2e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ35676.1 - 1.6e-13 50.3 0.0 4.2e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ35676.1 - 8e-06 25.6 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EEQ35676.1 - 0.011 13.6 0.3 0.013 13.4 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CASP_C PF08172.7 EEQ35676.1 - 0.036 13.0 0.1 0.049 12.6 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal EMP24_GP25L PF01105.19 EEQ35676.1 - 0.062 13.0 0.9 0.085 12.5 0.6 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Troponin PF00992.15 EEQ35676.1 - 0.063 13.3 6.2 0.085 12.9 4.3 1.1 1 0 0 1 1 1 0 Troponin Flagellin_C PF00700.16 EEQ35676.1 - 0.095 12.8 0.3 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Nup35_RRM_2 PF14605.1 EEQ35676.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif IncA PF04156.9 EEQ35676.1 - 0.23 11.0 1.5 0.29 10.7 1.1 1.1 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EEQ35676.1 - 0.49 10.7 4.3 0.83 9.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EEQ35676.1 - 1 8.8 4.4 1.7 8.2 3.0 1.3 1 0 0 1 1 1 0 Septum formation initiator SUZ PF12752.2 EEQ35677.1 - 2.4e-21 76.0 3.0 2.4e-21 76.0 2.1 2.8 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EEQ35677.1 - 1.6e-09 37.2 0.0 3.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.1 EEQ35678.1 - 0.014 15.0 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle LEP503 PF15221.1 EEQ35678.1 - 0.11 12.1 0.1 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 Antimicrobial18 PF08130.6 EEQ35678.1 - 0.3 11.0 3.6 7.3 6.5 0.2 2.8 2 0 0 2 2 2 0 Type A lantibiotic family cwf18 PF08315.7 EEQ35679.1 - 3.6e-38 130.9 7.2 3.6e-38 130.9 5.0 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.1 EEQ35680.1 - 3.9e-23 81.1 0.0 5.5e-07 29.4 0.0 4.2 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EEQ35680.1 - 3.6e-19 67.3 0.2 0.00016 21.6 0.0 5.8 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.15 EEQ35680.1 - 1.1e-16 59.4 0.1 2e-05 24.2 0.0 5.4 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.2 EEQ35680.1 - 7.4e-13 47.7 0.0 3.6e-06 26.3 0.0 4.2 4 0 0 4 4 4 3 PPR repeat DUF1242 PF06842.7 EEQ35681.1 - 3.2e-14 52.1 4.2 1.3e-13 50.1 0.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.11 EEQ35682.1 - 6.6e-23 80.3 0.1 1.1e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EEQ35682.1 - 0.00068 19.7 0.2 0.0023 18.0 0.0 1.9 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EEQ35682.1 - 0.018 15.3 0.1 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 EEQ35682.1 - 0.038 14.1 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S JAB PF01398.16 EEQ35683.1 - 4.5e-17 61.8 0.0 8.1e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEQ35683.1 - 2.7e-15 56.4 0.1 4.9e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 EEQ35683.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF1253 PF06862.7 EEQ35684.1 - 8.6e-160 531.9 0.0 1e-159 531.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 EEQ35684.1 - 0.0008 18.9 0.0 0.029 13.8 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase EamA PF00892.15 EEQ35685.1 - 2.2e-17 63.2 24.8 8.5e-12 45.2 2.8 3.1 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EEQ35685.1 - 0.00054 20.1 29.6 0.00066 19.8 3.2 3.5 3 1 1 4 4 4 2 Multidrug resistance efflux transporter CTP_transf_2 PF01467.21 EEQ35686.1 - 8.2e-24 84.4 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase PP2C PF00481.16 EEQ35687.1 - 6e-81 271.5 0.0 9.1e-81 270.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEQ35687.1 - 0.00033 20.1 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LpxD PF04613.9 EEQ35687.1 - 0.065 12.7 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Acetyltransf_1 PF00583.19 EEQ35688.1 - 7.6e-14 51.5 1.7 1.2e-13 50.9 1.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEQ35688.1 - 1.1e-08 35.2 0.3 1.6e-08 34.7 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ35688.1 - 4e-08 33.3 0.2 5.8e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ35688.1 - 8.8e-07 28.5 0.1 1.5e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EEQ35688.1 - 1e-06 28.5 0.4 1.4e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ35688.1 - 2.9e-05 23.9 0.1 3.5e-05 23.7 0.1 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ35688.1 - 0.00036 20.3 0.4 0.00062 19.5 0.3 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EEQ35688.1 - 0.0052 16.3 0.4 0.0082 15.7 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEQ35688.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZART1 PF12554.3 EEQ35689.1 - 6.5e-23 79.9 1.4 9.6e-23 79.3 1.0 1.3 1 1 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated CUE PF02845.11 EEQ35690.1 - 1.5e-10 40.3 0.0 2.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain OB_NTP_bind PF07717.11 EEQ35691.1 - 2.8e-22 78.7 0.0 5.2e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEQ35691.1 - 1.8e-20 72.8 0.0 4.1e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ35691.1 - 4.3e-12 45.7 0.0 1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ35691.1 - 5.2e-06 26.0 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEQ35691.1 - 3.6e-05 23.9 0.0 8.8e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ35691.1 - 0.001 18.9 0.0 0.02 14.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EEQ35691.1 - 0.0019 17.1 0.1 0.011 14.6 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 EEQ35691.1 - 0.0026 17.3 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EEQ35691.1 - 0.0075 15.7 0.1 0.042 13.2 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EEQ35691.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EEQ35691.1 - 0.054 12.5 0.1 0.19 10.8 0.0 1.9 1 1 1 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EEQ35691.1 - 0.055 13.3 0.0 1.7 8.5 0.0 2.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEQ35691.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 1 0 ABC transporter NACHT PF05729.7 EEQ35691.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EEQ35691.1 - 0.18 12.1 1.4 1.2 9.4 0.5 2.5 2 1 0 2 2 1 0 AAA domain PITH PF06201.8 EEQ35692.1 - 1.2e-43 148.4 0.0 1.5e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.16 EEQ35693.1 - 4.2e-30 104.3 9.2 4.8e-30 104.1 6.3 1.0 1 0 0 1 1 1 1 Snf7 HSCB_C PF07743.8 EEQ35693.1 - 0.056 13.9 9.0 1.6 9.2 1.1 2.5 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF2203 PF09969.4 EEQ35693.1 - 0.13 12.4 4.0 1.9 8.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cactin_mid PF10312.4 EEQ35693.1 - 0.78 8.9 7.4 0.38 10.0 0.6 2.1 2 0 0 2 2 2 0 Conserved mid region of cactin Nsp1_C PF05064.8 EEQ35693.1 - 6.4 6.4 10.0 0.18 11.4 1.4 2.3 2 1 0 2 2 2 0 Nsp1-like C-terminal region AAA PF00004.24 EEQ35694.1 - 6e-91 301.5 0.0 1.2e-45 154.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ35694.1 - 3.5e-13 49.9 1.5 5.8e-05 23.1 0.0 4.3 3 2 1 4 4 3 2 AAA ATPase domain RuvB_N PF05496.7 EEQ35694.1 - 6.7e-13 48.2 0.0 5.1e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EEQ35694.1 - 8.1e-12 45.4 0.1 0.0043 17.1 0.0 5.1 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.9 EEQ35694.1 - 9e-11 41.9 0.0 0.00028 20.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EEQ35694.1 - 9.8e-11 41.7 0.0 4.4e-05 23.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEQ35694.1 - 1.3e-10 42.0 0.0 5.6e-05 23.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 EEQ35694.1 - 2.7e-10 40.0 0.1 0.0012 18.6 0.0 4.3 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEQ35694.1 - 5.9e-10 38.5 0.0 0.00044 19.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EEQ35694.1 - 2.7e-09 36.9 0.0 0.002 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EEQ35694.1 - 3.9e-09 35.7 0.0 0.00011 21.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EEQ35694.1 - 2.6e-08 33.5 0.3 0.0086 15.8 0.1 3.5 2 1 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EEQ35694.1 - 4.8e-08 33.1 0.0 0.0053 16.9 0.0 2.9 2 1 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EEQ35694.1 - 1.3e-07 31.7 0.0 0.0029 17.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EEQ35694.1 - 2.4e-07 30.3 0.4 0.027 13.8 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEQ35694.1 - 3.9e-07 29.4 0.5 0.019 14.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEQ35694.1 - 6.9e-07 28.9 0.0 0.0025 17.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEQ35694.1 - 9.1e-07 29.2 0.1 0.013 15.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EEQ35694.1 - 2.1e-06 27.5 0.1 0.12 11.9 0.0 3.8 4 0 0 4 4 3 2 NACHT domain AAA_25 PF13481.1 EEQ35694.1 - 8e-06 25.3 4.3 1.4 8.3 0.0 4.5 2 2 2 4 4 4 2 AAA domain Cytidylate_kin2 PF13189.1 EEQ35694.1 - 2.7e-05 24.1 0.0 0.0085 16.0 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.22 EEQ35694.1 - 3e-05 24.3 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter KaiC PF06745.8 EEQ35694.1 - 4.7e-05 22.6 0.2 0.49 9.4 0.0 3.5 3 1 1 4 4 4 2 KaiC Sigma54_activ_2 PF14532.1 EEQ35694.1 - 6.2e-05 23.0 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EEQ35694.1 - 8e-05 22.1 0.0 0.33 10.4 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EEQ35694.1 - 0.0001 21.6 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein SKI PF01202.17 EEQ35694.1 - 0.00011 22.1 0.0 0.37 10.6 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase Arch_ATPase PF01637.13 EEQ35694.1 - 0.00015 21.5 0.0 2.2 7.8 0.0 3.6 2 2 1 3 3 3 2 Archaeal ATPase AFG1_ATPase PF03969.11 EEQ35694.1 - 0.00036 19.4 0.0 0.13 11.0 0.0 2.7 2 1 0 2 2 2 1 AFG1-like ATPase ResIII PF04851.10 EEQ35694.1 - 0.00042 20.2 0.0 0.96 9.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EEQ35694.1 - 0.00044 19.1 0.0 0.27 10.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.10 EEQ35694.1 - 0.00052 18.8 0.0 0.25 9.9 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 EEQ35694.1 - 0.001 17.9 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.13 EEQ35694.1 - 0.0011 18.5 0.0 0.74 9.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EEQ35694.1 - 0.0017 17.3 0.0 0.048 12.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 EEQ35694.1 - 0.0043 16.6 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EEQ35694.1 - 0.0045 16.6 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EEQ35694.1 - 0.0047 16.4 0.0 0.8 9.1 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 EEQ35694.1 - 0.014 14.9 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EEQ35694.1 - 0.016 14.8 0.0 0.39 10.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EEQ35694.1 - 0.022 14.4 0.0 3.6 7.2 0.0 2.9 2 1 0 3 3 3 0 NTPase IPT PF01745.11 EEQ35694.1 - 0.047 12.8 0.1 6.3 5.8 0.0 2.6 3 0 0 3 3 2 0 Isopentenyl transferase DUF2075 PF09848.4 EEQ35694.1 - 0.066 12.1 0.0 4.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EEQ35694.1 - 0.092 13.0 0.4 2.9 8.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 EEQ35694.1 - 0.3 10.4 1.7 19 4.5 0.0 3.8 5 1 0 5 5 5 0 AAA-like domain BOP1NT PF08145.7 EEQ35695.1 - 2.1e-104 348.8 5.9 3.2e-104 348.2 4.1 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EEQ35695.1 - 2.7e-26 90.4 9.4 2.5e-11 43.0 0.2 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EEQ35695.1 - 0.004 17.3 2.3 7.4 6.9 0.0 4.4 4 0 0 4 4 4 2 PQQ-like domain Zn_clus PF00172.13 EEQ35696.1 - 2.6e-08 33.6 8.1 5.9e-08 32.5 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GIDA_assoc_3 PF13932.1 EEQ35696.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 GidA associated domain 3 Leo1 PF04004.8 EEQ35697.1 - 5.2e-34 117.4 0.0 5.2e-34 117.4 0.0 1.6 2 0 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.12 EEQ35698.1 - 4.5e-21 75.2 1.9 5e-14 52.3 0.3 3.1 2 1 1 3 3 3 3 Mob1/phocein family IF-2B PF01008.12 EEQ35699.1 - 1.4e-55 188.2 8.0 1.7e-47 161.7 2.3 3.0 2 1 0 2 2 2 2 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.20 EEQ35700.1 - 2.6e-40 136.6 0.6 3e-40 136.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF2433 PF10360.4 EEQ35702.1 - 0.061 13.6 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) Ribosomal_L17 PF01196.14 EEQ35703.1 - 1.4e-32 112.0 0.0 2.2e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Metallophos_2 PF12850.2 EEQ35704.1 - 9e-17 61.3 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEQ35704.1 - 0.035 13.4 0.3 3.5 6.9 0.0 2.1 1 1 0 2 2 2 0 Calcineurin-like phosphoesterase PMP22_Claudin PF00822.15 EEQ35706.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF202 PF02656.10 EEQ35708.1 - 1.6e-12 47.4 5.0 1.6e-12 47.4 3.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4234 PF14018.1 EEQ35708.1 - 0.019 14.6 1.3 0.024 14.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF2207 PF09972.4 EEQ35708.1 - 0.14 10.6 1.3 0.15 10.6 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2615 PF11027.3 EEQ35708.1 - 0.18 11.7 1.6 0.29 11.0 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF805 PF05656.9 EEQ35708.1 - 6 6.7 7.1 11 5.8 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Tctex-1 PF03645.8 EEQ35709.1 - 1.1e-25 89.3 0.1 8.2e-25 86.5 0.0 2.0 1 1 0 1 1 1 1 Tctex-1 family WD40 PF00400.27 EEQ35710.1 - 3.5e-43 143.9 19.2 1.9e-11 43.4 0.2 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EEQ35710.1 - 7.5e-06 24.3 4.1 0.1 10.7 0.0 4.5 3 1 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEQ35710.1 - 0.0099 14.6 0.2 1.3 7.7 0.0 3.4 1 1 1 2 2 2 1 Nup133 N terminal like DUF3312 PF11768.3 EEQ35710.1 - 0.11 10.7 0.0 0.17 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Filament PF00038.16 EEQ35711.1 - 0.0082 15.6 1.5 0.013 15.0 1.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein p450 PF00067.17 EEQ35713.1 - 7.6e-67 225.8 0.0 9.4e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.1 EEQ35713.1 - 0.19 11.6 1.0 4 7.4 0.1 2.6 3 0 0 3 3 3 0 Stirrup p450 PF00067.17 EEQ35714.1 - 8.7e-30 103.6 0.2 1.1e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 HNH_2 PF13391.1 EEQ35715.1 - 2.4e-12 46.4 0.4 5.7e-12 45.2 0.3 1.7 1 0 0 1 1 1 1 HNH endonuclease TFIIF_alpha PF05793.7 EEQ35715.1 - 0.93 7.7 3.4 1.4 7.2 2.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ketoacyl-synt PF00109.21 EEQ35716.1 - 1.1e-72 244.5 0.0 2.2e-72 243.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ35716.1 - 1.5e-40 139.5 0.0 2.5e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEQ35716.1 - 9.3e-31 106.1 0.5 3e-30 104.5 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EEQ35716.1 - 8e-30 104.7 0.0 1.7e-29 103.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 EEQ35716.1 - 3e-14 52.8 0.0 7.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EEQ35716.1 - 2.1e-11 43.9 8.0 7.2e-06 26.1 0.5 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EEQ35716.1 - 0.00012 22.0 0.1 0.0013 18.6 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ35716.1 - 0.00038 20.2 0.0 0.84 9.3 0.0 3.0 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EEQ35716.1 - 0.046 12.7 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain FMO-like PF00743.14 EEQ35717.1 - 2.4e-50 171.2 0.0 6.8e-42 143.3 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEQ35717.1 - 2.2e-18 67.0 0.0 1.3e-16 61.3 0.0 3.0 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ35717.1 - 1.2e-07 30.9 0.1 8e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEQ35717.1 - 5.8e-05 22.9 0.0 0.0061 16.3 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEQ35717.1 - 0.0011 18.9 0.0 0.013 15.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EEQ35717.1 - 0.021 14.6 0.1 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.1 EEQ35717.1 - 0.03 14.3 0.0 0.081 12.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 EEQ35717.1 - 0.078 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain YaaC PF14175.1 EEQ35717.1 - 0.089 11.7 0.4 0.15 10.9 0.1 1.5 2 0 0 2 2 2 0 YaaC-like Protein IlvN PF07991.7 EEQ35717.1 - 0.11 11.8 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EEQ35717.1 - 0.18 10.9 0.0 20 4.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EEQ35717.1 - 0.18 12.1 0.8 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EEQ35718.1 - 3.4e-18 66.1 3.3 3.2e-16 59.6 2.3 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ35718.1 - 1e-08 35.0 0.1 2.5e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ35718.1 - 3.8e-08 33.4 0.0 0.0007 19.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EEQ35718.1 - 0.018 14.0 0.1 0.026 13.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EEQ35718.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fasciclin PF02469.17 EEQ35719.1 - 3.5e-34 117.5 0.0 1.3e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Cu-oxidase_3 PF07732.10 EEQ35720.1 - 2e-37 127.5 1.2 6e-37 125.9 0.3 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEQ35720.1 - 8.1e-23 80.4 13.8 1.2e-20 73.4 0.6 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EEQ35720.1 - 1.6e-18 67.0 0.0 4.9e-18 65.5 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase Methyltransf_2 PF00891.13 EEQ35721.1 - 9.2e-33 113.4 0.0 1.2e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EEQ35721.1 - 0.061 13.8 0.0 0.38 11.2 0.0 2.4 3 1 0 3 3 3 0 Methyltransferase domain MFS_1 PF07690.11 EEQ35722.1 - 5.5e-36 123.9 45.2 2.1e-35 122.0 31.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ35722.1 - 2.2e-14 52.9 21.8 6.5e-13 48.0 1.0 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 EEQ35722.1 - 0.00062 18.3 10.6 0.00062 18.3 7.3 3.2 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like WTF PF03303.8 EEQ35722.1 - 0.36 10.2 1.5 0.78 9.1 1.0 1.6 1 0 0 1 1 1 0 WTF protein Fungal_trans PF04082.13 EEQ35723.1 - 6.2e-18 64.6 0.9 9.8e-18 63.9 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ35723.1 - 6e-09 35.6 12.0 1.3e-08 34.5 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 EEQ35724.1 - 1.9e-18 66.2 1.4 3.1e-18 65.6 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ35724.1 - 2.8e-06 27.1 0.0 8.6e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like VASP_tetra PF08776.6 EEQ35725.1 - 0.032 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 VASP tetramerisation domain p450 PF00067.17 EEQ35726.1 - 1.9e-21 76.1 0.1 1.6e-19 69.7 0.0 2.4 3 0 0 3 3 3 2 Cytochrome P450 3Beta_HSD PF01073.14 EEQ35728.1 - 5.5e-51 172.9 0.0 6.9e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEQ35728.1 - 6.7e-29 100.9 0.0 9.2e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEQ35728.1 - 4.7e-11 42.0 0.1 1.9e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EEQ35728.1 - 3e-08 32.9 0.0 3.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEQ35728.1 - 3e-08 33.8 0.0 4.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEQ35728.1 - 0.00012 21.1 0.1 0.00087 18.2 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EEQ35728.1 - 0.0013 18.6 0.6 0.0053 16.6 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ35728.1 - 0.0023 17.6 0.3 0.012 15.2 0.2 2.0 1 1 0 1 1 1 1 KR domain Atx10homo_assoc PF09759.4 EEQ35728.1 - 0.098 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain TrkA_N PF02254.13 EEQ35728.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain MASE1 PF05231.9 EEQ35728.1 - 0.15 11.0 0.7 0.24 10.4 0.5 1.2 1 0 0 1 1 1 0 MASE1 Transket_pyr PF02779.19 EEQ35729.1 - 6.4e-40 136.5 0.0 1.3e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEQ35729.1 - 6.8e-30 103.5 0.1 2e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Reo_sigmaC PF04582.7 EEQ35731.1 - 0.00051 19.3 10.4 0.0062 15.7 1.1 2.3 2 0 0 2 2 2 2 Reovirus sigma C capsid protein DUF641 PF04859.7 EEQ35731.1 - 0.34 10.6 24.8 0.061 13.0 3.3 4.2 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) IncA PF04156.9 EEQ35731.1 - 1.7 8.2 33.1 1.3 8.6 3.8 3.3 3 0 0 3 3 3 0 IncA protein TMF_DNA_bd PF12329.3 EEQ35731.1 - 4.6 7.1 39.7 0.26 11.1 5.5 5.6 3 3 2 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF21 PF01595.15 EEQ35732.1 - 1e-21 77.0 0.1 4.3e-20 71.7 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EEQ35732.1 - 0.00013 21.7 0.4 0.078 12.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain His_Phos_1 PF00300.17 EEQ35733.1 - 7.1e-14 52.1 0.1 1.7e-13 50.9 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DsrC PF04358.8 EEQ35733.1 - 0.084 13.1 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 DsrC like protein HECT PF00632.20 EEQ35734.1 - 3.5e-72 243.2 0.0 5.9e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 EEQ35735.1 - 9e-36 122.0 12.3 3.5e-29 100.8 1.5 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EEQ35735.1 - 1.5e-09 37.6 11.2 8.9e-05 22.5 1.3 4.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ35735.1 - 1.6e-07 31.2 8.3 9.1e-06 25.7 1.7 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEQ35735.1 - 7.3e-05 22.5 4.2 0.0042 16.9 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2024 PF09630.5 EEQ35735.1 - 0.0055 16.4 0.3 0.021 14.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2024) Cytochrome_CBB3 PF13442.1 EEQ35735.1 - 0.16 12.1 2.2 17 5.6 0.1 2.9 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome-c551 PF10643.4 EEQ35735.1 - 0.29 10.4 1.0 5 6.3 0.1 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 zf-C2H2 PF00096.21 EEQ35735.1 - 0.48 10.8 16.4 0.3 11.5 0.2 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type Abhydrolase_3 PF07859.8 EEQ35737.1 - 6.8e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EEQ35737.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EEQ35737.1 - 0.0016 17.6 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ35737.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ35737.1 - 0.062 13.1 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 EEQ35738.1 - 6.3e-71 238.5 0.0 7.5e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35738.1 - 3.3e-31 108.3 0.0 4.2e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ35738.1 - 0.00014 20.9 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ35738.1 - 0.0089 15.7 0.0 0.018 14.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEQ35738.1 - 0.019 13.8 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EEQ35738.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 2OG-FeII_Oxy_2 PF13532.1 EEQ35739.1 - 2.4e-32 112.3 0.0 1.9e-31 109.4 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2HC_2 PF13913.1 EEQ35740.1 - 0.0037 16.9 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EEQ35740.1 - 0.0085 16.1 0.1 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EEQ35740.1 - 0.031 14.6 0.3 0.097 13.0 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ35740.1 - 0.13 12.7 0.5 0.3 11.5 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sigma_reg_N PF13800.1 EEQ35741.1 - 0.00075 19.4 1.2 0.002 18.1 0.8 1.8 1 0 0 1 1 1 1 Sigma factor regulator N-terminal DUF1129 PF06570.6 EEQ35741.1 - 0.0038 16.5 0.1 0.0067 15.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) DUF912 PF06024.7 EEQ35741.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CD34_antigen PF06365.7 EEQ35741.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF872 PF05915.7 EEQ35741.1 - 0.029 14.2 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF3671 PF12420.3 EEQ35741.1 - 0.048 13.6 0.1 0.048 13.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function Prominin PF05478.6 EEQ35741.1 - 0.08 10.4 0.0 0.1 10.1 0.0 1.1 1 0 0 1 1 1 0 Prominin Synaptobrevin PF00957.16 EEQ35741.1 - 0.17 11.5 1.6 0.38 10.3 1.1 1.6 1 0 0 1 1 1 0 Synaptobrevin DUF4234 PF14018.1 EEQ35741.1 - 0.74 9.5 4.4 2.6 7.8 2.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Pox_P35 PF03213.9 EEQ35741.1 - 1 8.2 4.2 1.6 7.6 2.9 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein DUF3753 PF12575.3 EEQ35741.1 - 1.7 8.5 6.5 0.16 11.7 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) FAD_binding_3 PF01494.14 EEQ35743.1 - 1e-11 44.5 0.2 8.6e-07 28.3 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain Imm_superinfect PF14373.1 EEQ35743.1 - 0.0003 20.3 2.5 0.00076 19.0 1.7 1.7 1 0 0 1 1 1 1 Superinfection immunity protein DAO PF01266.19 EEQ35743.1 - 0.012 14.5 2.4 1.2 7.9 0.0 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ35743.1 - 0.018 13.8 0.2 0.13 11.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.11 EEQ35745.1 - 1.2e-42 145.9 42.8 1.2e-42 145.9 29.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ35745.1 - 0.001 17.4 6.8 0.001 17.4 4.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PepSY_TM_2 PF13703.1 EEQ35745.1 - 0.027 14.6 0.3 0.027 14.6 0.2 4.5 6 1 0 6 6 6 0 PepSY-associated TM helix Fungal_trans PF04082.13 EEQ35746.1 - 9.2e-11 41.0 0.0 2.4e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ35746.1 - 2.7e-08 33.5 9.3 2.7e-08 33.5 6.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EEQ35747.1 - 2.4e-70 236.8 0.0 4.7e-70 235.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ35747.1 - 8.5e-49 166.5 0.1 1.6e-48 165.7 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EEQ35747.1 - 7.4e-46 156.0 0.0 1.6e-45 155.0 0.0 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EEQ35747.1 - 3.6e-42 144.5 0.0 6.3e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EEQ35747.1 - 1.6e-37 128.9 0.0 3.7e-37 127.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEQ35747.1 - 1.4e-29 102.3 0.2 1.4e-29 102.3 0.1 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EEQ35747.1 - 7.6e-18 64.8 0.0 1.8e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ35747.1 - 2.2e-12 47.2 0.0 6.6e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ35747.1 - 4.6e-12 45.9 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ35747.1 - 7.4e-09 35.3 0.0 2.6e-08 33.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ35747.1 - 3.2e-07 30.8 0.0 1e-06 29.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ35747.1 - 1.3e-05 24.4 0.0 2.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEQ35747.1 - 1.6e-05 24.9 0.0 0.0003 20.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EEQ35747.1 - 2.4e-05 24.4 0.2 6.8e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EEQ35747.1 - 7.8e-05 21.7 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 EEQ35747.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 EEQ35747.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 EEQ35747.1 - 0.046 12.7 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.12 EEQ35747.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AA_permease_2 PF13520.1 EEQ35748.1 - 4e-54 183.7 41.6 5.1e-54 183.4 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ35748.1 - 8.8e-25 86.9 38.7 1.2e-24 86.5 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease Plasmod_dom_1 PF09715.5 EEQ35748.1 - 0.13 12.2 2.5 0.14 12.0 0.2 2.3 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Na_Ca_ex PF01699.19 EEQ35749.1 - 0.029 13.9 2.4 0.076 12.6 1.7 1.8 1 1 0 1 1 1 0 Sodium/calcium exchanger protein Vma12 PF11712.3 EEQ35749.1 - 0.065 12.9 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3237 PF11578.3 EEQ35750.1 - 8.1e-09 34.9 0.0 2e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) DLH PF01738.13 EEQ35751.1 - 1.7e-07 30.7 0.0 3.1e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EEQ35751.1 - 0.0023 17.5 0.0 0.0045 16.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ35751.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ35751.1 - 0.069 13.0 0.1 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cu-oxidase_3 PF07732.10 EEQ35752.1 - 3.8e-46 155.6 0.3 4.8e-45 152.0 0.2 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEQ35752.1 - 8.8e-40 135.4 4.4 6.5e-37 126.1 0.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EEQ35752.1 - 8.1e-34 116.8 0.0 2.5e-33 115.2 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase LysM PF01476.15 EEQ35754.1 - 6e-13 48.4 0.1 1.9e-06 27.6 0.0 3.5 3 0 0 3 3 3 3 LysM domain Lamp PF01299.12 EEQ35754.1 - 3.9 6.5 6.1 2.9 6.9 3.2 1.5 1 1 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) MFS_1 PF07690.11 EEQ35755.1 - 2.8e-26 92.0 50.0 9.9e-18 63.9 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ35755.1 - 0.0001 22.0 1.4 1.7 8.4 0.1 3.7 3 1 1 4 4 4 2 MFS_1 like family Sugar_tr PF00083.19 EEQ35755.1 - 0.00065 18.3 23.0 0.0048 15.5 3.1 2.7 1 1 0 2 2 2 2 Sugar (and other) transporter Cutinase PF01083.17 EEQ35756.1 - 4.3e-42 143.8 0.8 6e-42 143.3 0.6 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EEQ35756.1 - 4.6e-06 26.2 0.0 8.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EEQ35756.1 - 0.0027 17.5 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EEQ35756.1 - 0.068 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEQ35756.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Flocculin_t3 PF13928.1 EEQ35756.1 - 0.073 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Flocculin type 3 repeat UPF0565 PF10561.4 EEQ35756.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 RED_N PF07808.8 EEQ35758.1 - 9.3e-10 38.1 1.6 9.3e-10 38.1 1.1 2.5 3 0 0 3 3 3 1 RED-like protein N-terminal region PspA_IM30 PF04012.7 EEQ35758.1 - 0.0032 16.8 0.3 0.0086 15.4 0.2 1.6 1 0 0 1 1 1 1 PspA/IM30 family Glyco_hydro_cc PF11790.3 EEQ35760.1 - 2.5e-59 200.6 0.2 3.1e-59 200.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Peptidase_S8 PF00082.17 EEQ35761.1 - 0.0043 16.2 0.1 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Myb_DNA-bind_6 PF13921.1 EEQ35762.1 - 1.4e-24 85.9 1.7 8.5e-14 51.4 0.0 3.3 1 1 2 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ35762.1 - 9.7e-23 79.9 10.5 1.2e-11 44.5 0.1 4.0 3 2 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EEQ35762.1 - 0.0056 16.7 4.7 0.82 9.8 0.1 3.4 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EEQ35762.1 - 0.041 13.7 1.7 0.96 9.3 0.1 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 EEQ35762.1 - 0.44 10.4 7.4 12 5.8 0.2 4.4 3 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain FAD_binding_4 PF01565.18 EEQ35764.1 - 2.1e-06 27.2 0.0 5.6e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EEQ35764.1 - 0.0019 18.0 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like PsbT PF01405.12 EEQ35764.1 - 0.038 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein YycH PF07435.6 EEQ35764.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 YycH protein adh_short PF00106.20 EEQ35765.1 - 1.7e-18 67.1 0.2 2.2e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ35765.1 - 8.2e-09 35.3 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ35765.1 - 9e-06 25.6 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EEQ35765.1 - 0.0032 17.2 0.2 0.0064 16.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EEQ35765.1 - 0.0063 16.5 0.0 0.025 14.6 0.0 2.0 2 1 0 2 2 2 1 NADH(P)-binding AA_permease PF00324.16 EEQ35766.1 - 3.3e-116 388.4 34.8 3.8e-116 388.2 24.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ35766.1 - 4.8e-32 111.0 37.7 6.4e-32 110.6 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease HTH_29 PF13551.1 EEQ35767.1 - 3.2e-07 30.4 0.6 7.5e-07 29.2 0.2 1.9 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EEQ35767.1 - 9.1e-06 26.3 1.5 0.00014 22.5 0.1 2.6 1 1 2 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EEQ35767.1 - 1.1e-05 24.8 0.1 2.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.1 EEQ35767.1 - 3e-05 23.4 1.8 8.5e-05 22.0 0.3 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EEQ35767.1 - 0.00021 20.7 0.1 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.11 EEQ35767.1 - 0.0009 18.4 0.4 0.12 11.6 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_7 PF02796.10 EEQ35767.1 - 0.00099 18.9 0.2 0.97 9.3 0.1 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase GerE PF00196.14 EEQ35767.1 - 0.0028 16.9 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.1 EEQ35767.1 - 0.007 16.3 3.3 0.0091 15.9 0.9 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain DNA_binding_1 PF01035.15 EEQ35767.1 - 0.012 15.3 0.1 5.6 6.7 0.0 2.8 2 1 1 3 3 3 0 6-O-methylguanine DNA methyltransferase, DNA binding domain HTH_Tnp_Tc3_2 PF01498.13 EEQ35767.1 - 0.016 15.2 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_31 PF13560.1 EEQ35767.1 - 0.035 14.3 0.3 0.035 14.3 0.2 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.17 EEQ35767.1 - 0.059 13.2 0.3 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix HTH_Mga PF08280.6 EEQ35767.1 - 0.094 12.4 0.0 9 6.1 0.0 2.3 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain KGG PF10685.4 EEQ35768.1 - 2.4e-23 81.4 22.7 2.3e-10 40.1 0.2 3.5 4 0 0 4 4 4 3 Stress-induced bacterial acidophilic repeat motif VanY PF02557.12 EEQ35768.1 - 0.13 12.1 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Aminotran_5 PF00266.14 EEQ35769.1 - 3.9e-18 65.3 0.0 1.7e-17 63.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EEQ35769.1 - 0.015 14.2 0.0 0.034 13.1 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II UNC-93 PF05978.11 EEQ35770.1 - 6.8e-05 22.4 3.0 6.8e-05 22.4 2.1 2.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 WD40 PF00400.27 EEQ35771.1 - 9.1e-64 209.2 19.2 1.2e-12 47.2 0.4 8.4 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EEQ35771.1 - 1.3e-10 40.0 0.3 0.018 13.1 0.0 4.9 2 2 3 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EEQ35771.1 - 9.6e-07 28.6 0.0 0.037 13.7 0.0 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 EEQ35771.1 - 0.0056 15.6 0.2 0.39 9.5 0.0 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF1513) PD40 PF07676.7 EEQ35771.1 - 0.0098 15.5 2.3 3.2 7.5 0.1 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EEQ35771.1 - 0.11 11.5 0.2 18 4.3 0.0 3.1 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 EEQ35771.1 - 0.17 11.0 0.0 44 3.1 0.0 3.4 3 1 0 3 3 3 0 TUP1-like enhancer of split DUF3312 PF11768.3 EEQ35771.1 - 0.22 9.7 0.0 0.38 8.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF936 PF06075.7 EEQ35771.1 - 1.5 7.6 14.4 2.2 7.0 10.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Exo_endo_phos PF03372.18 EEQ35772.1 - 1.4e-15 57.8 0.3 2e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thi4 PF01946.12 EEQ35773.1 - 8.3e-100 332.6 0.0 9.9e-100 332.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EEQ35773.1 - 1.8e-07 30.4 0.1 2.5e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEQ35773.1 - 2.6e-05 23.3 0.2 4.7e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEQ35773.1 - 2.9e-05 24.0 0.1 0.00015 21.7 0.1 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEQ35773.1 - 0.0012 18.6 0.1 0.0041 16.9 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEQ35773.1 - 0.0043 16.9 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ35773.1 - 0.0061 16.6 0.0 0.0081 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ35773.1 - 0.05 12.4 0.2 0.14 10.9 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EEQ35773.1 - 0.06 12.3 0.1 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EEQ35773.1 - 0.063 11.9 0.2 0.088 11.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 EEQ35773.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ppx-GppA PF02541.11 EEQ35775.1 - 2.8e-40 138.2 0.0 5e-40 137.4 0.0 1.4 1 1 0 1 1 1 1 Ppx/GppA phosphatase family LINES_C PF14695.1 EEQ35775.1 - 0.086 12.0 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Lines C-terminus Proteasome PF00227.21 EEQ35777.1 - 6.1e-48 162.6 0.2 7.3e-48 162.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 EEQ35777.1 - 0.085 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Pkinase PF00069.20 EEQ35778.1 - 6.4e-33 113.9 0.0 2.4e-32 112.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35778.1 - 2.8e-06 26.5 0.0 0.027 13.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEQ35778.1 - 0.02 14.6 0.3 0.21 11.3 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pil1 PF13805.1 EEQ35779.1 - 8.6e-86 287.4 1.8 1e-85 287.2 1.3 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3452 PF11934.3 EEQ35779.1 - 0.047 12.9 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) SWI-SNF_Ssr4 PF08549.5 EEQ35781.1 - 2.3e-207 690.4 11.1 2.6e-207 690.2 7.7 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) GATase PF00117.23 EEQ35782.1 - 7.1e-08 32.1 0.0 4.9e-06 26.1 0.0 2.1 1 1 1 2 2 2 2 Glutamine amidotransferase class-I HTS PF04204.11 EEQ35782.1 - 0.029 13.0 0.0 0.47 9.1 0.0 2.0 1 1 0 2 2 2 0 Homoserine O-succinyltransferase Peptidase_C26 PF07722.8 EEQ35782.1 - 0.11 11.9 0.1 0.23 10.8 0.1 1.6 1 1 0 1 1 1 0 Peptidase C26 AMP-binding PF00501.23 EEQ35783.1 - 2.1e-150 500.7 0.0 1.4e-77 260.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEQ35783.1 - 5.5e-62 209.3 0.0 2e-32 112.2 0.0 3.5 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EEQ35783.1 - 2.8e-21 75.5 0.1 7.3e-10 38.9 0.0 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ35783.1 - 6.9e-15 55.7 0.0 1.2e-06 29.3 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Asn_synthase PF00733.16 EEQ35784.1 - 4.1e-53 180.4 0.0 6.1e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EEQ35784.1 - 1.1e-36 125.3 0.0 2.3e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EEQ35784.1 - 3.4e-32 111.1 0.0 9.8e-32 109.7 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EEQ35784.1 - 0.00012 21.3 0.0 0.00024 20.3 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.11 EEQ35784.1 - 0.0022 16.6 0.0 0.0035 15.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 EEQ35784.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 NAD synthase adh_short PF00106.20 EEQ35786.1 - 1.2e-14 54.5 0.0 2.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EEQ35786.1 - 5.9e-06 25.8 0.0 7.7e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEQ35786.1 - 9.7e-05 22.4 0.0 0.00017 21.6 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EEQ35786.1 - 0.00011 21.9 0.1 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 KR domain FAD_binding_4 PF01565.18 EEQ35787.1 - 3.7e-18 65.3 2.7 5.6e-18 64.7 1.4 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EEQ35787.1 - 7.6e-07 28.9 0.1 1.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like RNA_pol_Rpb2_6 PF00562.23 EEQ35788.1 - 4.1e-117 391.1 0.0 5.3e-117 390.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEQ35788.1 - 3.6e-33 114.2 0.0 5e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EEQ35788.1 - 1.6e-26 92.9 0.0 3e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EEQ35788.1 - 5.3e-24 83.7 0.0 1.1e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EEQ35788.1 - 1.2e-23 82.8 0.1 3e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EEQ35788.1 - 5.9e-15 55.2 0.0 2.8e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EEQ35788.1 - 0.0013 18.6 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ketoacyl-synt PF00109.21 EEQ35789.1 - 2.6e-61 207.3 0.0 6.7e-61 205.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEQ35789.1 - 8.5e-59 199.4 0.0 2e-58 198.1 0.0 1.6 1 1 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EEQ35789.1 - 3.5e-56 189.7 0.0 1.9e-55 187.3 0.0 2.2 3 0 0 3 3 2 1 KR domain PS-DH PF14765.1 EEQ35789.1 - 1.8e-49 168.5 0.0 2.7e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EEQ35789.1 - 5.7e-44 149.9 0.0 2e-43 148.2 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEQ35789.1 - 9.7e-27 93.1 0.0 7.1e-26 90.3 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EEQ35789.1 - 1.3e-18 66.7 0.0 4.1e-18 65.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EEQ35789.1 - 3.1e-17 62.8 0.0 2.7e-16 59.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ35789.1 - 2.6e-11 43.3 0.0 6.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ35789.1 - 2.9e-11 43.3 0.0 1.3e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EEQ35789.1 - 3.8e-11 43.9 0.0 2e-10 41.6 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EEQ35789.1 - 3.8e-09 36.9 0.2 3.8e-08 33.7 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ35789.1 - 2.5e-08 34.4 0.0 9.1e-08 32.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ35789.1 - 0.001 18.5 0.0 0.0029 17.0 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase ADH_N PF08240.7 EEQ35789.1 - 0.0015 18.2 0.0 0.0054 16.4 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 EEQ35789.1 - 0.0016 17.2 0.0 0.0029 16.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 EEQ35789.1 - 0.0019 18.4 0.0 0.0086 16.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ35789.1 - 0.0056 15.8 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEQ35789.1 - 0.039 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EEQ35789.1 - 0.053 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Thiolase_N PF00108.18 EEQ35789.1 - 0.097 11.6 0.1 0.2 10.6 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain PP-binding PF00550.20 EEQ35789.1 - 0.15 12.3 0.2 0.63 10.3 0.0 2.2 2 0 0 2 2 1 0 Phosphopantetheine attachment site Arf PF00025.16 EEQ35790.1 - 1.7e-38 131.6 0.0 1.2e-35 122.2 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 EEQ35790.1 - 4.2e-16 58.7 0.0 5.4e-14 51.8 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EEQ35790.1 - 3.7e-11 43.5 0.0 6.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ35790.1 - 8.5e-06 25.7 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EEQ35790.1 - 1.6e-05 23.8 0.0 3e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 EEQ35790.1 - 4.7e-05 22.6 0.0 0.00032 19.9 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEQ35790.1 - 0.00017 20.9 0.0 0.0012 18.0 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EEQ35790.1 - 0.0015 18.3 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 Dynamin family RCR PF12273.3 EEQ35791.1 - 3.2e-24 85.9 11.7 4.9e-24 85.3 8.1 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4131 PF13567.1 EEQ35791.1 - 0.0068 15.8 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF1183 PF06682.7 EEQ35791.1 - 0.0075 15.9 0.5 0.009 15.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Ion_trans_2 PF07885.11 EEQ35791.1 - 0.014 15.1 0.2 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Ion channel LSR PF05624.9 EEQ35791.1 - 0.088 12.5 2.2 0.13 12.0 1.5 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Rhabdo_glycop PF00974.13 EEQ35791.1 - 0.18 9.9 0.7 0.25 9.5 0.5 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Tetraspannin PF00335.15 EEQ35791.1 - 0.21 10.8 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 Tetraspanin family Shisa PF13908.1 EEQ35791.1 - 0.45 10.6 10.0 1 9.5 6.9 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PROL5-SMR PF15621.1 EEQ35791.1 - 0.92 9.9 14.1 1.4 9.3 9.8 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Corona_S2 PF01601.11 EEQ35792.1 - 0.042 11.9 15.2 0.056 11.5 10.6 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein MFS_1 PF07690.11 EEQ35793.1 - 3.4e-15 55.6 26.7 3.4e-15 55.6 18.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ35793.1 - 3e-07 29.3 34.4 4.3e-06 25.5 3.2 4.3 3 1 1 4 4 4 4 Sugar (and other) transporter SR-25 PF10500.4 EEQ35794.1 - 0.21 11.0 8.1 0.31 10.4 5.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CwfJ_C_2 PF04676.9 EEQ35795.1 - 2.4e-25 88.8 0.7 5.8e-25 87.6 0.5 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EEQ35795.1 - 2.6e-24 85.1 0.0 7.6e-24 83.6 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 IGF2_C PF08365.6 EEQ35795.1 - 0.088 12.5 1.5 0.24 11.2 1.1 1.7 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide Toxin_38 PF14866.1 EEQ35795.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Potassium channel toxin DRIM PF07539.7 EEQ35796.1 - 6.6e-43 145.5 0.0 2.8e-42 143.4 0.0 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis zf-DNL PF05180.7 EEQ35797.1 - 3.6e-28 97.0 0.3 5.4e-28 96.4 0.2 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 EEQ35797.1 - 0.00062 19.2 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 CSL zinc finger TFIIS_C PF01096.13 EEQ35797.1 - 0.0064 16.0 1.2 0.93 9.1 0.1 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Elf1 PF05129.8 EEQ35797.1 - 0.054 13.2 0.3 0.09 12.4 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 EEQ35797.1 - 0.32 10.7 2.1 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EEQ35797.1 - 0.91 9.3 6.0 2.8 7.8 0.6 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EEQ35797.1 - 0.94 9.1 0.1 0.94 9.1 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Cullin PF00888.17 EEQ35798.1 - 7.2e-127 424.3 6.6 1.1e-126 423.8 4.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEQ35798.1 - 1.2e-28 98.7 0.3 5.7e-28 96.5 0.2 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain HWE_HK PF07536.9 EEQ35798.1 - 0.014 15.8 0.1 0.12 12.8 0.0 2.6 2 0 0 2 2 2 0 HWE histidine kinase DUF1737 PF08410.5 EEQ35798.1 - 0.016 14.9 0.1 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Rrf2 PF02082.15 EEQ35798.1 - 0.051 13.7 0.2 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator Sld5 PF05916.6 EEQ35799.1 - 2.9e-06 27.5 0.1 6.2e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 GINS complex protein Rhodanese PF00581.15 EEQ35800.1 - 4e-13 49.7 0.0 8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Iso_dh PF00180.15 EEQ35802.1 - 1e-86 291.0 0.0 1.2e-86 290.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 EEQ35802.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA DNA_pol_phi PF04931.8 EEQ35803.1 - 8.8e-45 152.7 49.5 5.1e-34 117.1 33.5 3.2 2 1 0 2 2 2 2 DNA polymerase phi Uteroglobin PF01099.12 EEQ35803.1 - 0.021 14.6 0.2 0.59 9.9 0.0 3.1 2 0 0 2 2 2 0 Uteroglobin family BUD22 PF09073.5 EEQ35803.1 - 0.93 8.4 31.4 0.17 10.9 18.7 2.0 2 0 0 2 2 2 0 BUD22 TPT PF03151.11 EEQ35804.1 - 2.1e-29 102.1 14.2 2.1e-29 102.1 9.8 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EEQ35804.1 - 2.3e-05 24.4 35.9 0.00011 22.2 9.1 2.9 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EEQ35804.1 - 0.00017 20.6 24.2 0.00017 20.6 16.8 1.6 1 1 0 1 1 1 1 UAA transporter family AD PF09793.4 EEQ35805.1 - 5.5e-23 80.6 0.0 1.1e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain RRM_1 PF00076.17 EEQ35806.1 - 4.5e-18 64.6 0.0 7.5e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ35806.1 - 1.2e-10 41.1 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ35806.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EEQ35806.1 - 0.15 11.6 0.2 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain GKAP PF03359.8 EEQ35806.1 - 0.49 9.9 7.3 0.89 9.1 5.0 1.4 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Macoilin PF09726.4 EEQ35806.1 - 4.9 5.3 9.8 6.7 4.8 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 6PGD PF00393.14 EEQ35807.1 - 7.4e-133 442.2 0.0 9.1e-133 441.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EEQ35807.1 - 1.1e-50 171.6 0.0 1.6e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EEQ35807.1 - 0.037 14.0 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Peptidase_C15 PF01470.12 EEQ35808.1 - 1.4e-14 54.4 0.0 5.1e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase Porphobil_deam PF01379.15 EEQ35812.1 - 1.5e-08 33.8 0.0 2.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EEQ35812.1 - 0.00014 21.8 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain AA_permease PF00324.16 EEQ35813.1 - 1.8e-108 362.9 38.8 2.2e-108 362.6 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ35813.1 - 5.7e-27 94.3 40.9 7e-27 94.0 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EEQ35813.1 - 0.039 12.4 0.0 0.056 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) SPC12 PF06645.8 EEQ35813.1 - 0.077 12.8 1.3 0.46 10.3 0.9 2.4 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) HET PF06985.6 EEQ35814.1 - 2e-28 99.2 0.2 5.8e-23 81.5 0.1 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) AP_endonuc_2 PF01261.19 EEQ35816.1 - 1.8e-24 86.2 0.1 2.7e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 EEQ35817.1 - 1.9e-43 147.2 0.2 3.8e-43 146.2 0.0 1.6 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EEQ35817.1 - 5.6e-14 51.9 0.0 5.5e-13 48.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ35817.1 - 6.2e-05 22.1 0.0 0.00025 20.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 EEQ35817.1 - 0.00011 22.0 0.0 0.00033 20.4 0.0 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 PI3K_1B_p101 PF10486.4 EEQ35817.1 - 0.035 11.6 0.1 0.053 11.1 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BSP_II PF05432.6 EEQ35818.1 - 0.14 11.4 4.9 0.21 10.8 3.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pox_Ag35 PF03286.9 EEQ35818.1 - 2.8 7.4 10.3 5.6 6.4 1.5 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Hexokinase_2 PF03727.11 EEQ35819.1 - 3.2e-26 92.0 0.0 9.5e-22 77.3 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EEQ35819.1 - 2.8e-24 85.5 0.0 4.4e-23 81.6 0.0 2.3 1 1 0 1 1 1 1 Hexokinase Lipoprotein_19 PF13617.1 EEQ35819.1 - 0.7 9.5 3.7 0.52 9.9 0.3 2.5 3 0 0 3 3 3 0 YnbE-like lipoprotein DUF3237 PF11578.3 EEQ35821.1 - 5e-07 29.1 0.0 6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ADH_N PF08240.7 EEQ35822.1 - 1.1e-12 47.6 1.3 1.1e-12 47.6 0.9 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ35822.1 - 7.1e-08 32.0 0.1 1.5e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 EEQ35823.1 - 2e-13 49.8 0.7 3.2e-13 49.1 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ35823.1 - 7.5e-10 38.5 8.6 1.4e-09 37.6 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 EEQ35824.1 - 3.6e-09 36.4 0.3 0.0051 16.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ35824.1 - 5.7e-07 29.6 1.6 20 6.1 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ35824.1 - 8.4e-07 29.2 0.2 13 6.2 0.0 6.2 4 2 2 6 6 6 0 Tetratricopeptide repeat NB-ARC PF00931.17 EEQ35824.1 - 6.1e-06 25.2 0.0 1.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 EEQ35824.1 - 1.6e-05 24.3 0.1 1.2 9.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ35824.1 - 6.6e-05 22.5 0.0 0.32 11.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 EEQ35824.1 - 0.0032 17.6 0.0 0.02 15.0 0.0 2.2 1 1 0 2 2 2 1 AAA domain TPR_16 PF13432.1 EEQ35824.1 - 0.0032 18.0 0.3 22 5.8 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ35824.1 - 0.006 16.1 1.0 0.5 10.0 0.0 3.4 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.23 EEQ35824.1 - 0.0068 15.9 0.0 5 6.9 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ35824.1 - 0.063 13.2 1.0 19 5.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ35824.1 - 0.86 10.2 4.0 9.6 6.9 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-UBR PF02207.15 EEQ35825.1 - 1.6e-14 53.3 19.5 1.6e-14 53.3 13.5 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EEQ35825.1 - 8.5e-05 22.2 0.0 0.00027 20.6 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Mago-bind PF09282.5 EEQ35826.1 - 2.1e-13 49.5 1.9 3.4e-13 48.8 1.3 1.3 1 0 0 1 1 1 1 Mago binding Trypan_PARP PF05887.6 EEQ35826.1 - 0.61 9.9 7.0 0.94 9.2 4.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF913 PF06025.7 EEQ35826.1 - 2.2 6.9 4.6 2.9 6.5 3.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Amino_oxidase PF01593.19 EEQ35827.1 - 3.5e-16 59.3 0.1 8.9e-15 54.6 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEQ35827.1 - 2.6e-13 49.7 0.0 6.6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ35827.1 - 8.9e-09 34.7 0.1 1.6e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEQ35827.1 - 1.2e-05 25.1 0.0 0.00074 19.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEQ35827.1 - 0.00033 20.7 0.0 0.006 16.6 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ35827.1 - 0.0009 17.8 0.1 0.0021 16.5 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EEQ35827.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEQ35827.1 - 0.0019 17.3 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ35827.1 - 0.0057 15.5 0.1 0.0089 14.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEQ35827.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EEQ35827.1 - 0.016 15.6 0.0 0.05 14.0 0.0 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ35827.1 - 0.033 12.4 0.0 0.046 11.9 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Glucokinase PF02685.11 EEQ35827.1 - 0.042 12.6 0.2 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Glucokinase Strep_67kDa_ant PF06100.6 EEQ35827.1 - 0.13 10.5 0.1 0.26 9.5 0.0 1.5 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family GIDA PF01134.17 EEQ35827.1 - 0.14 10.9 0.3 0.31 9.8 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-CCCH_2 PF14608.1 EEQ35828.1 - 1e-05 25.3 52.7 1.5e-05 24.7 7.1 5.7 5 1 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EEQ35828.1 - 0.0081 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) p450 PF00067.17 EEQ35829.1 - 9.4e-62 209.0 0.0 5.5e-44 150.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 2-Hacid_dh_C PF02826.14 EEQ35831.1 - 1.3e-53 180.7 0.0 2.1e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ35831.1 - 5.9e-36 122.8 0.1 9.8e-36 122.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 EEQ35831.1 - 0.0055 17.0 0.0 0.015 15.6 0.0 1.7 2 0 0 2 2 2 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 EEQ35831.1 - 0.0075 15.8 2.2 0.54 9.8 0.7 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EEQ35831.1 - 0.014 15.2 0.2 0.051 13.4 0.0 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 EEQ35831.1 - 0.016 15.6 0.3 6.6 7.2 0.0 2.8 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EEQ35831.1 - 0.031 14.0 0.6 0.079 12.7 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EEQ35831.1 - 0.086 12.3 0.0 0.086 12.3 0.0 2.3 3 0 0 3 3 3 0 ACT domain Fe-ADH PF00465.14 EEQ35832.1 - 4.6e-102 341.3 0.0 6e-102 341.0 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEQ35832.1 - 4.2e-17 62.2 0.0 2.1e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EEQ35832.1 - 0.00026 20.4 0.1 0.00047 19.6 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Toprim_3 PF13362.1 EEQ35832.1 - 0.066 13.4 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 Toprim domain Ank_2 PF12796.2 EEQ35833.1 - 2.8e-80 264.7 16.0 2.3e-17 63.0 0.3 7.1 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ35833.1 - 3.7e-71 231.6 18.1 1.1e-08 34.4 0.0 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_3 PF13606.1 EEQ35833.1 - 2e-59 191.5 13.5 2.5e-06 27.2 0.0 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 EEQ35833.1 - 2.8e-57 190.1 19.8 1.1e-11 44.8 0.6 8.4 4 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ35833.1 - 2.9e-51 170.3 18.2 6.6e-07 29.3 0.0 10.2 3 1 5 10 10 10 10 Ankyrin repeats (many copies) DUF4265 PF14085.1 EEQ35833.1 - 0.02 14.6 0.1 0.62 9.8 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4265) Glyco_hydro_2 PF00703.16 EEQ35834.1 - 3.8e-12 46.6 0.0 1.7e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EEQ35834.1 - 8.1e-08 32.0 0.1 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF3553 PF12073.3 EEQ35834.1 - 0.56 9.5 2.4 1 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3553) Kin17_mid PF10357.4 EEQ35835.1 - 8.9e-47 157.8 1.3 8.9e-47 157.8 0.9 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EEQ35835.1 - 3.2e-05 23.9 0.9 8e-05 22.7 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ35835.1 - 0.00012 22.1 0.3 0.00012 22.1 0.2 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEQ35835.1 - 0.015 15.4 0.4 0.015 15.4 0.3 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Glyoxalase PF00903.20 EEQ35836.1 - 1e-38 132.2 0.1 8.1e-19 67.8 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEQ35836.1 - 5e-32 110.7 0.1 1.7e-15 57.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EEQ35836.1 - 4.3e-25 87.8 0.0 1.4e-07 31.5 0.0 4.0 1 1 3 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EEQ35836.1 - 7.3e-08 32.5 0.0 0.0065 16.3 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.1 EEQ35836.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 CppA N-terminal FCH PF00611.18 EEQ35838.1 - 0.0065 16.6 1.0 0.017 15.2 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.13 EEQ35838.1 - 0.27 10.7 3.2 0.18 11.3 0.8 1.7 2 0 0 2 2 2 0 BAR domain DHC PF09626.5 EEQ35838.1 - 0.33 11.6 3.6 0.64 10.6 0.3 2.4 2 1 0 2 2 2 0 Dihaem cytochrome c Arrestin_C PF02752.17 EEQ35839.1 - 4.3e-15 56.0 0.0 1.8e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEQ35839.1 - 1.2e-12 47.8 0.0 7.3e-12 45.3 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CTD PF12815.2 EEQ35839.1 - 0.065 13.6 3.3 0.71 10.2 0.1 2.3 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 LDB19 PF13002.2 EEQ35839.1 - 0.11 12.0 0.0 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 Arrestin_N terminal like Hexapep PF00132.19 EEQ35840.1 - 2.2e-06 26.9 9.4 0.00027 20.3 2.1 4.2 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEQ35840.1 - 1.7e-05 24.2 2.0 0.0016 17.9 0.3 2.7 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EEQ35840.1 - 0.017 13.6 0.1 0.023 13.2 0.1 1.1 1 0 0 1 1 1 0 L-fucokinase Phostensin PF13914.1 EEQ35840.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region An_peroxidase PF03098.10 EEQ35841.1 - 2.6e-94 316.4 0.0 7.1e-74 249.0 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 EEQ35841.1 - 6.4e-09 34.8 0.0 6.1e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.4 EEQ35843.1 - 1.8e-104 349.0 0.2 2.5e-104 348.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MARVEL PF01284.18 EEQ35845.1 - 2e-07 30.9 2.9 2.8e-07 30.4 2.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Acyl_transf_3 PF01757.17 EEQ35845.1 - 0.044 12.6 5.2 0.061 12.1 3.6 1.2 1 0 0 1 1 1 0 Acyltransferase family Patched PF02460.13 EEQ35845.1 - 2.5 5.9 4.6 3.4 5.4 3.2 1.1 1 0 0 1 1 1 0 Patched family PGA2 PF07543.7 EEQ35846.1 - 1.8e-36 124.9 1.3 2.1e-36 124.7 0.9 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CDC45 PF02724.9 EEQ35846.1 - 0.039 12.0 1.0 0.04 11.9 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Remorin_C PF03763.8 EEQ35846.1 - 0.055 12.9 0.8 0.055 12.9 0.5 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region DUF3245 PF11595.3 EEQ35846.1 - 6.3 7.0 12.7 0.27 11.5 3.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) CENP-S PF15630.1 EEQ35847.1 - 9.8e-31 105.7 0.0 1.3e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EEQ35847.1 - 3.5e-06 26.5 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EEQ35847.1 - 0.0059 16.3 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EEQ35847.1 - 0.0085 15.8 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit MMS1_N PF10433.4 EEQ35848.1 - 2.5e-74 250.2 0.0 8e-74 248.5 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EEQ35848.1 - 3.2e-63 213.7 0.0 3.9e-62 210.2 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region PQQ_2 PF13360.1 EEQ35848.1 - 6.3e-05 22.5 0.7 0.53 9.6 0.1 3.1 3 0 0 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 EEQ35848.1 - 0.032 14.5 5.2 0.31 11.3 0.1 4.7 5 0 0 5 5 5 0 PQQ-like domain NAD_binding_2 PF03446.10 EEQ35849.1 - 2.8e-36 124.8 0.1 4.7e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EEQ35849.1 - 5e-30 104.0 0.0 8.6e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EEQ35849.1 - 4.6e-07 30.1 0.0 1.8e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EEQ35849.1 - 0.00058 19.0 0.0 0.00096 18.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EEQ35849.1 - 0.004 17.6 0.0 0.009 16.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ABC_membrane PF00664.18 EEQ35850.1 - 1.5e-63 214.8 33.7 7.9e-35 120.6 6.9 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ35850.1 - 2.2e-44 151.0 0.1 1.9e-25 89.7 0.0 4.4 2 2 1 3 3 3 3 ABC transporter SMC_N PF02463.14 EEQ35850.1 - 1.1e-14 54.2 0.0 9.4e-06 25.0 1.2 3.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ35850.1 - 2.9e-10 40.5 0.0 5.4e-06 26.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EEQ35850.1 - 7.6e-05 22.5 0.8 0.14 12.0 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EEQ35850.1 - 0.00091 18.7 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ35850.1 - 0.0012 18.8 0.3 0.076 12.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 EEQ35850.1 - 0.0013 17.9 0.0 0.0029 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEQ35850.1 - 0.0018 18.4 2.7 0.025 14.7 0.0 3.3 4 0 0 4 4 3 1 AAA domain ABC_ATPase PF09818.4 EEQ35850.1 - 0.0041 15.7 0.1 0.32 9.5 0.0 2.8 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 EEQ35850.1 - 0.0068 15.8 1.0 0.055 12.8 0.1 2.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EEQ35850.1 - 0.01 16.6 0.2 0.027 15.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EEQ35850.1 - 0.013 15.6 0.1 6.1 7.0 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEQ35850.1 - 0.031 14.0 0.0 0.74 9.6 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EEQ35850.1 - 0.051 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EEQ35850.1 - 0.066 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EEQ35850.1 - 0.13 12.1 0.0 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EEQ35850.1 - 0.14 11.9 0.1 0.71 9.5 0.0 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FAD_binding_4 PF01565.18 EEQ35851.1 - 4.1e-23 81.4 5.8 8.9e-23 80.3 4.0 1.6 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 EEQ35852.1 - 4.2e-36 124.4 0.0 2.4e-22 79.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 EEQ35853.1 - 6.6e-25 87.5 50.3 1.8e-24 86.1 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 EEQ35854.1 - 3.7e-07 29.9 11.4 3.7e-07 29.9 7.9 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ35855.1 - 1e-17 63.9 0.0 1.9e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ35855.1 - 1.4e-09 37.6 8.9 2.7e-09 36.7 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trp_DMAT PF11991.3 EEQ35856.1 - 2e-108 362.8 0.1 6.1e-108 361.2 0.0 1.6 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.23 EEQ35857.1 - 7.2e-155 515.4 0.0 9.6e-81 271.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEQ35857.1 - 9.5e-73 244.6 0.0 1.2e-40 139.2 0.0 2.2 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EEQ35857.1 - 7.8e-25 86.9 0.1 2.3e-08 34.1 0.0 3.6 3 0 0 3 3 3 3 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EEQ35857.1 - 3.2e-10 40.1 0.0 0.00023 21.4 0.0 2.8 2 0 0 2 2 2 2 HxxPF-repeated domain AMP-binding_C PF13193.1 EEQ35857.1 - 2.9e-06 28.1 0.0 3.9e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EEQ35857.1 - 0.022 13.2 0.0 0.11 10.9 0.0 1.9 2 0 0 2 2 2 0 Transferase family Methyltransf_2 PF00891.13 EEQ35858.1 - 6.3e-32 110.6 0.0 9.3e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEQ35858.1 - 0.00062 20.3 0.0 0.0017 18.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ35858.1 - 0.00063 19.4 0.0 0.0061 16.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ35858.1 - 0.036 14.1 0.0 1.1 9.3 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain HTH_6 PF01418.12 EEQ35858.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family DUF4218 PF13960.1 EEQ35858.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Methyltransf_12 PF08242.7 EEQ35858.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DIT1_PvcA PF05141.7 EEQ35859.1 - 1.4e-61 208.2 0.0 2.3e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Transferase PF02458.10 EEQ35859.1 - 1.7e-16 59.7 0.0 8.3e-08 31.0 0.0 3.1 3 0 0 3 3 3 3 Transferase family PP-binding PF00550.20 EEQ35859.1 - 5.4e-08 32.9 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 EEQ35859.1 - 2.5e-07 29.4 0.0 0.0058 15.0 0.0 3.2 1 1 2 3 3 3 2 AMP-binding enzyme DUF3984 PF13136.1 EEQ35859.1 - 1.9 7.6 3.8 3.2 6.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) MFS_1 PF07690.11 EEQ35860.1 - 3.3e-18 65.5 59.4 6.4e-14 51.4 22.7 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MVL PF12151.3 EEQ35861.1 - 0.66 9.6 4.2 9.1 6.0 1.0 2.4 2 0 0 2 2 2 0 Mannan-binding protein MFS_1 PF07690.11 EEQ35862.1 - 4.1e-13 48.7 71.3 5.5e-10 38.4 27.8 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ35862.1 - 0.00063 18.0 25.2 0.00082 17.6 17.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF912 PF06024.7 EEQ35862.1 - 0.12 12.4 0.8 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WSC PF01822.14 EEQ35863.1 - 4.2e-48 161.1 44.6 1.5e-18 66.4 7.8 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.6 EEQ35863.1 - 6.2e-31 107.3 0.0 6e-29 100.8 0.0 3.1 3 1 0 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EEQ35863.1 - 7.3e-23 80.5 0.1 1.6e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 EEQ35863.1 - 0.04 13.7 0.2 0.46 10.3 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Glyco_hydro_16 PF00722.16 EEQ35864.1 - 4.1e-19 68.5 2.8 4e-18 65.3 0.4 2.7 1 1 2 3 3 3 2 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 EEQ35865.1 - 4.9e-48 163.4 11.1 8e-48 162.7 3.4 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF3471 PF11954.3 EEQ35865.1 - 0.016 15.0 0.0 0.046 13.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) Glycos_transf_2 PF00535.21 EEQ35865.1 - 0.057 13.0 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 WSC PF01822.14 EEQ35866.1 - 2.4e-38 129.9 32.4 3.4e-19 68.5 8.3 2.5 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.18 EEQ35866.1 - 1.6e-20 73.5 0.2 3.7e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.13 EEQ35866.1 - 0.0032 17.4 0.1 0.0084 16.1 0.1 1.7 1 0 0 1 1 1 1 Photosystem I psaG / psaK Pterin_4a PF01329.14 EEQ35867.1 - 1.5e-21 75.9 0.2 1.8e-21 75.6 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase FR47 PF08445.5 EEQ35869.1 - 0.0058 16.3 0.1 0.69 9.7 0.0 2.3 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.19 EEQ35869.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Peptidase_S8 PF00082.17 EEQ35871.1 - 2.4e-46 158.1 5.7 4.1e-46 157.3 3.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ35871.1 - 1.2e-18 67.4 0.1 2e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 p450 PF00067.17 EEQ35873.1 - 9.8e-20 70.4 0.0 3.2e-16 58.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Zn_clus PF00172.13 EEQ35875.1 - 4.6e-06 26.4 8.6 8.3e-06 25.6 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEQ35876.1 - 0.1 11.3 10.1 0.26 9.9 7.0 1.7 1 1 0 1 1 1 0 Major Facilitator Superfamily TRI12 PF06609.8 EEQ35877.1 - 1.4e-06 26.8 9.6 3e-06 25.7 6.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EEQ35877.1 - 6.8e-06 25.0 19.2 0.00021 20.1 13.3 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ35877.1 - 0.00052 18.7 4.3 0.00052 18.7 3.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2530 PF10745.4 EEQ35877.1 - 0.26 11.2 2.8 0.47 10.4 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2530)